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Sample records for fr12my10r flutriafol pesticide

  1. 75 FR 26668 - Flutriafol; Pesticide Tolerances

    Science.gov (United States)

    2010-05-12

    ... skin sensitizer when tested in guinea pigs. The pattern of toxicity attributed to flutriafol exposure... production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311...

  2. Flutriafol and pyraclostrobin residues in Brazilian green coffees.

    Science.gov (United States)

    de Oliveira, Luiz Alberto Bandeira; Pacheco, Henrique Poltronieri; Scherer, Rodrigo

    2016-01-01

    The aim of this work was to monitor flutriafol and pyraclostrobin residues in Brazilian green coffees. More than 10,000 samples were analyzed. The pesticides were extracted using the QuEChERS method and analyzed by LC-MS/MS. The validated method is fast, with 5 min runs, and efficient, as precision and accuracy showed RSD no greater than 5% and recoveries within the 88-119% range. LOQ for flutriafol and pyraclostrobin were 0.005 mg/kg. The results of the analyzed samples showed that the percentage of nonconformities regarding flutriafol increased throughout the years, with over 1200 samples (11.8%). On the other hand, just 15 samples (0.15%) presented residues above 10 μg/kg for pyraclostrobin. Considering that flutriafol is a toxic and carcinogenic pesticide, as well as the increase in the number of irregularities throughout the years, it becomes important to implement public actions to assure consumer safety. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Theoretical and experimental insights into the ·OH-mediated mineralization mechanism of flutriafol

    International Nuclear Information System (INIS)

    Liu, Siqi; Zhou, Xiezhen; Han, Weiqing; Li, Jiansheng; Sun, Xiuyun; Shen, Jinyou; Wang, Lianjun

    2017-01-01

    Highlights: • A complete ·OH-mediated degradation pathway of flutriafol is proposed. • Computational approach is effective to reveal the favorable transformation process. • The electrochemical experiments well verify the theoretical results. - Abstract: Flutriafol is one of the widely used triazole fungicides in global pesticides market, and its degradation mechanisms are important to develop powerful technologies to remove it. Insight into the kinetics and mechanisms of ·OH-mediated mineralization of flutriafol have been obtained using quantum chemical calculation and electrochemical experiment methods. The complete ·OH-mediated degradation pathway of flutriafol was proposed by density functional theory (DFT) simulation and the potential energy surface was mapped out for possible reactions. On the basis of DFT calculations, the optimal ·OH-mediated mineralization mechanism of flutriafol was revealed, and a series of intermediates were observed accumulated in the degradation process, most significance among which were (2-fluorophenyl) (4-fluorophenyl)-Methanone, phenol, dihydroxybenzenes, benzoquinones, muconic acids, maleic acids, oxalic acids and formic acid. To give deeper insight into the ·OH-mediated reaction mechanism, the electrostatic potential (ESP) and average local ionization energy (ALIE) analysis were conducted for o-benzoquinone and p-benzoquinone. The proposed mechanism was further validated by electrochemical experiments at TiO_2-NTs/SnO_2-Sb/PbO_2 anode. The main intermediates were identified and quantified by experimental method, indicating that the proposed ·OH-mediated degradation mechanism derived from DFT calculations was feasible. These detailed findings could be instrumental for a comprehensive understanding of the ·OH-mediated mineralization mechanism of flutriafol and the similar contaminants.

  4. 75 FR 4383 - Pesticide Products: Registration Applications

    Science.gov (United States)

    2010-01-27

    ..., Biopesticides and Pollution Prevention Division (7511P), Office of Pesticide Programs, Environmental Protection..., Biopesticides and Pollution Prevention Division, Office of Pesticide Programs. [FR Doc. 2010-1582 Filed 1-26-10...

  5. Control of Vascular Streak Dieback Disease of Cocoa with Flutriafol Fungicides

    Directory of Open Access Journals (Sweden)

    Febrilia Nur'aini

    2014-12-01

    Full Text Available Vascular streak dieback caused by the fungus Oncobasidium theobromae is one of the important diseases in cocoa crop in Indonesia. One approach to control the disease is by using fungicides. The aim of this research was to determine the effect of class triazole fungicides to the intensity of the vascular streak dieback disease on cocoa seedling phase, immature and mature cocoa. Experiments were conducted in Kotta Blater, PTPN XII and Kaliwining, Indonesian  Coffee and Cocoa Research Institute. Flutriafol 250 g/l with a concentration 0,05%, 0,1% and 0,15% foliar sprayed on cocoa seedlings, immature and mature cocoa. Active compound combination of Azoxystrobin and Difenoconazole with 0,1% concentration used as a comparation fungicides. The result showed that Flutriafol with 0,05%, 0,1% and 0,15% concentration and Azoxystrobin & Difenoconazol with 0,1% concentration could suppress the vascular streak dieback disease on seedlings. On immature plants, the application of Flutriafol was not effectively suppress the vascular streak dieback disease whereas the fungicide comparison could suppress with the efficacy level of 46.22%. On mature plants,both of fungicides could not suppress the vascular streak dieback disease. Key words: Fungicide, cocoa, vascular streak dieback, triazole, flutriafol, azoxystrobin+difenoconazol

  6. 75 FR 1773 - Notice of Receipt of a Pesticide Petition Filed for Residues of Polymeric Polyhydroxy Acid in or...

    Science.gov (United States)

    2010-01-13

    ... telephone number is (703) 305-5805. FOR FURTHER INFORMATION CONTACT: Menyon Adams, Biopesticides and..., Biopesticides and Pollution Prevention Division, Office of Pesticide Programs. [FR Doc. 2010-490; Filed 1-12-10...

  7. 75 FR 62323 - Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Change to...

    Science.gov (United States)

    2010-10-08

    ... Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Change to Labeling... the pesticide container and containment regulations to provide an 8-month extension of the labeling... titled ``Pesticide Management and Disposal; Standards for Pesticide Containers and Containment'' (71 FR...

  8. 75 FR 16111 - Antimicrobial Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-03-31

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2009-0935; FRL-8807-1] Antimicrobial Pesticide... . List of Subjects Environmental protection, Antimicrobial pesticides and pest. Dated: March 15, 2010. Joan Harrigan Farrelly, Director, Antimicrobial Division, Office of Pesticide Programs. [FR Doc. 2010...

  9. 75 FR 57019 - Pesticide Product Registrations; Conditional Approval

    Science.gov (United States)

    2010-09-17

    ..., the Agency was able to make basic health and safety determinations which show that use of flutriafol... unreasonable adverse effects to man and the environment. III. Conditional Approval Form EPA issued a notice...

  10. A facile-operation tubular electro-Fenton system combined with oxygen evolution reaction for flutriafol degradation: Modeling and Parameters optimizing

    International Nuclear Information System (INIS)

    Xu, Anlin; Wei, Kajia; Zhang, Yonghao; Han, Weiqing; Li, Jiansheng; Sun, Xiuyun; Shen, Jinyou; Wang, Lianjun

    2017-01-01

    Highlights: •A novel tubular cathode coated by carbon black and Fe 2 O 3 -NPs was fabricated and tested. •Effective flutriafol degradation of in dual tubular EF reactor was optimized by RSM. •Ti/RuO 2 and Ti/SnO 2 -Sb anode as oxygen provider can reach high oxygen utilization (78.8%). •The best flutriafol removal (76.5%) without circulation was gained if Ti/RuO 2 was selected as anode. •The simplest operation by the EOC process without aeration, pH and iron adjustment was obtained in the system. -- Abstract: An effective tubular membrane cathode coated by heterogeneous Fe 2 O 3 nanoparticles with carbon black (CB), combined with oxygen evolution reaction (OER), was fabricated to simplify the operation of electro-Fenton system. It was demonstrated that the cathode had a favorable suitability for this system owing to the excellent performance presented on Field emission scanning electron microscopy (FE-SEM), Transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS) and Cyclic voltammetry (CV). An optimal condition was obtained by response surface methodology (RSM) including pH of 6.7, current density of 13.0 A m −2 , membrane flux of 82.9 L m −2 h −1 , and CB/Fe of 6.2:1. Meanwhile, we achieved an estimated degradation efficiency of flutriafol (79.6%) in optimal condition without circulation of the influent. Effects of OER on the degradation of flutriafol via Ti/RuO 2 and Ti/SnO 2 -Sb tubular anodes were further interpreted by the gas production rate and the H 2 /O 2 value. High oxygen utilization of 78.8% was acquired when Ti/RuO 2 anode served as a sufficient oxygen provider. The electrocatalytic oxygen cycle, a key loop process, was firstly interpreted in this system, which achieved a great comprehensive electrocatalytic effect with the simplest operation and had a 74.5% removal of flutriafol in the verified experiment.

  11. 76 FR 69642 - Flutriafol; Pesticide Tolerances

    Science.gov (United States)

    2011-11-09

    ... tested in guinea pigs. Short-term, subchronic, and chronic toxicity studies in rats, mice, and dogs...: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code...

  12. 77 FR 47296 - Flutriafol; Pesticide Tolerances

    Science.gov (United States)

    2012-08-08

    ... guinea pigs. Short-term, subchronic, and chronic toxicity studies in rats, mice, and dogs identified the... those engaged in the following activities: Crop production (NAICS code 111). Animal production (NAICS...

  13. 78 FR 75257 - Flutriafol; Pesticide Tolerances

    Science.gov (United States)

    2013-12-11

    ... States Department of Agriculture's (USDA) National Health and Nutrition Examination Survey, What We Eat... also seen. Effects in the offspring (decreased litter size and percentage of live births, increased pup... Food and Agriculture Organization/World Health Organization food standards program, and it is...

  14. Solar System constraints to general f(R) gravity

    International Nuclear Information System (INIS)

    Chiba, Takeshi; Smith, Tristan L.; Erickcek, Adrienne L.

    2007-01-01

    It has been proposed that cosmic acceleration or inflation can be driven by replacing the Einstein-Hilbert action of general relativity with a function f(R) of the Ricci scalar R. Such f(R) gravity theories have been shown to be equivalent to scalar-tensor theories of gravity that are incompatible with Solar System tests of general relativity, as long as the scalar field propagates over Solar System scales. Specifically, the parameterized post-Newtonian (PPN) parameter in the equivalent scalar-tensor theory is γ=1/2, which is far outside the range allowed by observations. In response to a flurry of papers that questioned the equivalence of f(R) theory to scalar-tensor theories, it was recently shown explicitly, without resorting to the scalar-tensor equivalence, that the vacuum field equations for 1/R gravity around a spherically symmetric mass also yield γ=1/2. Here we generalize this analysis to f(R) gravity and enumerate the conditions that, when satisfied by the function f(R), lead to the prediction that γ=1/2

  15. 75 FR 807 - Pesticide Tolerance Crop Grouping Program II; Revision to General Tolerance Regulations

    Science.gov (United States)

    2010-01-06

    .... pubescens Ruiz & Pav., Capsicum spp.; (12) Roselle, Hibiscus sabdariffa L.; (13) Scarlet eggplant, Solanum..., specialty crop producers, pesticide registrants, the environment, or human health. No crop group tolerance... Environmental Health Risks and Safety Risks (62 FR 19885, April 23, 1997) does not apply to this proposed rule...

  16. 77 FR 12295 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2012-02-29

    ........ Pollution Prevention Division (7511P), Office of Pesticide Programs, Environmental Protection Agency, 1200... 9); citrus fruits (crop group 10-10); pome fruits (crop group 11-10); stone fruits (crop group 12); berries and small fruits, bushberries (crop subgroup 13-07B); tree nuts (crop group 14); oilseeds (crop...

  17. MICROEXTRAÇÃO LÍQUIDO-LÍQUIDO DISPERSIVA ASSISTIDA POR VORTEX E ULTRASSOM APLICADA À DETERMINAÇÃO DE AGROTÓXICOS TRIAZINAS, TRIAZINONAS E O TRIAZOL FLUTRIAFOL EM ÁGUA

    Directory of Open Access Journals (Sweden)

    Jaqueline da Silva Duarte

    Full Text Available This study aimed at developing and validating a method for the simultaneous determination of triazines (ametryne, atrazine, prometryne and terbuthylazine, triazinones (metribuzin and hexazinone and a triazole (flutriafol in water by ultrasound vortex assisted dispersive liquid-liquid microextraction (USVADLLME and GC-MS. The experimental conditions that provided the best results were: 5.00 mL of sample, 100 mL of extractor solvent (toluene, vortex agitation for 30 s and sonication for 1 min. at 240 W and 40 ºC. The USVADLLME provided recoveries ranging from 77.2% to 109%, with a repetitivity and intermediate precision varying from 1.4 to 9.0% and 2.9 to 15%, respectively. The method detection limits ranged between 0.10 and 2.71 µg L-1. The method was applied to different surface water samples and a matrix effect was not observed. Once validated, the proposed method was applied to ten water samples of an important agricultural region of Mato Grosso State/Brazil, but none of the studied analytes were detected. The USVADLLME is proposed as an efficient, fast, simple and non-expensive alternative technique for the simultaneous determination of multiclass pesticides in water.

  18. A viable logarithmic f(R) model for inflation

    Energy Technology Data Exchange (ETDEWEB)

    Amin, M.; Khalil, S. [Center for Fundamental Physics, Zewail City of Science and Technology,6 October City, Giza (Egypt); Salah, M. [Center for Fundamental Physics, Zewail City of Science and Technology,6 October City, Giza (Egypt); Department of Mathematics, Faculty of Science, Cairo University,Giza (Egypt)

    2016-08-18

    Inflation in the framework of f(R) modified gravity is revisited. We study the conditions that f(R) should satisfy in order to lead to a viable inflationary model in the original form and in the Einstein frame. Based on these criteria we propose a new logarithmic model as a potential candidate for f(R) theories aiming to describe inflation consistent with observations from Planck satellite (2015). The model predicts scalar spectral index 0.9615r of order 10{sup −3}. Furthermore, we show that for a class of models, a natural coupling between inflation and a scalar boson is generated through the minimal coupling between gravity and matter fields and a reheating temperature less that 10{sup 9} GeV is obtained.

  19. My Journey from Python to R

    OpenAIRE

    Lorgat, Mohamed Wasim

    2018-01-01

    A lightning talk of my personal experiences in programming, from childhood with languages including Game Maker and DarkBASIC, to now with Python and R. I highlight the underlying principle which, I argue, separates the R community from others.See the reference for further reading material along this line.

  20. Pesticides in Wyoming Groundwater, 2008-10

    Science.gov (United States)

    Eddy-Miller, Cheryl A.; Bartos, Timothy T.; Taylor, Michelle L.

    2013-01-01

    Groundwater samples were collected from 296 wells during 1995-2006 as part of a baseline study of pesticides in Wyoming groundwater. In 2009, a previous report summarized the results of the baseline sampling and the statistical evaluation of the occurrence of pesticides in relation to selected natural and anthropogenic (human-related) characteristics. During 2008-10, the U.S. Geological Survey, in cooperation with the Wyoming Department of Agriculture, resampled a subset (52) of the 296 wells sampled during 1995-2006 baseline study in order to compare detected compounds and respective concentrations between the two sampling periods and to evaluate the detections of new compounds. The 52 wells were distributed similarly to sites used in the 1995-2006 baseline study with respect to geographic area and land use within the geographic area of interest. Because of the use of different types of reporting levels and variability in reporting-level values during both the 1995-2006 baseline study and the 2008-10 resampling study, analytical results received from the laboratory were recensored. Two levels of recensoring were used to compare pesticides—a compound-specific assessment level (CSAL) that differed by compound and a common assessment level (CAL) of 0.07 microgram per liter. The recensoring techniques and values used for both studies, with the exception of the pesticide 2,4-D methyl ester, were the same. Twenty-eight different pesticides were detected in samples from the 52 wells during the 2008-10 resampling study. Pesticide concentrations were compared with several U.S. Environmental Protection Agency drinking-water standards or health advisories for finished (treated) water established under the Safe Drinking Water Act. All detected pesticides were measured at concentrations smaller than U.S. Environmental Protection Agency drinking-water standards or health advisories where applicable (many pesticides did not have standards or advisories). One or more pesticides

  1. Stellar configurations in f(R) theories of gravity

    International Nuclear Information System (INIS)

    Henttunen, K.; Multamaeki, T.; Vilja, I.

    2008-01-01

    We study stellar configurations and the space-time around them in metric f(R) theories of gravity. In particular, we focus on the polytropic model of the Sun in two specific cases: the f(R)=R-μ 4 /R model and a model with a stabilizing higher order term f(R)=R-μ 4 /R+βR 3 /(3μ 4 ). We show how the stellar configuration in the f(R) theory can, by appropriate initial conditions, be selected to be equal to that described by the Lane-Emden equation and how a simple scaling relation exists between the solutions. We also derive the correct solution analytically near the center of the star in f(R) theory. Previous analytical and numerical results are confirmed, indicating that the space-time around the Sun is incompatible with solar system constraints in the f(R)=R-μ 4 /R model. Numerical work shows that stellar configurations, with a regular metric at the center, lead to γ PPN ≅1/2 outside the star for both models, i.e., the Schwarzschild-de Sitter space-time is not the correct vacuum solution for such configurations. This shows that even when one fine-tunes the initial conditions inside a star such that the mass of the effective scalar in the equivalent scalar-tensor theory is large, γ PPN is still 1/2 outside the star. Conversely, by selecting the Schwarzschild-de Sitter metric as the outside solution, or equivalently setting the mass of the effective scalar to be large outside the star, we find that the stellar configuration is unchanged but the metric is irregular at the center. The possibility of constructing a f(R) theory compatible with the solar system experiments and possible new constraints arising from the radius-mass relation of stellar objects is discussed

  2. 19 CFR 12.112 - Notice of arrival of pesticides and devices.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Notice of arrival of pesticides and devices. 12...; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Pesticides and Devices § 12.112 Notice of arrival of pesticides and devices. (a) General. An importer desiring to import pesticides or devices into the...

  3. Application of zirconium dioxide nanoparticle sorbent for the clean-up step in post-harvest pesticide residue analysis.

    Science.gov (United States)

    Uclés, Ana; Herrera López, Sonia; Dolores Hernando, Maria; Rosal, Roberto; Ferrer, Carmen; Fernández-Alba, Amadeo R

    2015-11-01

    The use of yttria-stabilized zirconium dioxide nanoparticles as d-SPE clean-up sorbent for a rapid and sensitive liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method for the determination of post-harvest fungicides (carbaryl, carbendazim, chlorpropham, diphenylamine, ethoxyquin, flutriafol, imazalil, iprodione, methomyl, myclobutanil, pirimiphos-methyl, prochloraz, pyrimethanil, thiabendazole, thiophanate-methyl and tolclofos-methyl) in orange and pear samples has been evaluated and validated. The sample preparation was a modification of the QuEChERS extraction method using yttria-stabilized zirconium dioxide and multi-walled carbon nanotubes (MWCNTs) nanoparticles as the solid phase extraction (d-SPE) clean-up sorbents prior to injecting the ten-fold diluted extracts into the LC system. By using the yttria-stabilized zirconium dioxide extraction method, more recoveries in the 70-120% range were obtained - thus this method was used for the validation. Quantification was carried out using a matrix-matched calibration curve which was linear in the 1-500 µg kg(-1) range for almost all the pesticides studied. The validated limit of quantification was 10 µg kg(-1) for most of the studied compounds, except chlorpropham, ethoxyquin and thiophanate-methyl. Pesticide recoveries at the 10 and 100 µg kg(-1) concentration levels were satisfactory, with values between 77% and 120% and relative standard deviations (RSD) lower than 10% (n=5). The developed method was applied for the determination of selected fungicides in 20 real orange and pear samples. Four different pesticide residues were detected in 10 of these commodities; 20% of the samples contained pesticide residues at a quantifiable level (equal to or above the LOQs) for at least one pesticide residue. The most frequently-detected pesticide residues were: carbendazim, thiabendazole and imazalil-all were below the MRL. The highest concentration found was imazalil at 1175 µg kg

  4. Future dynamics in f(R) theories

    International Nuclear Information System (INIS)

    Mueller, D.; Andrade, V.C. de; Maia, C.; Reboucas, M.J.; Teixeira, A.F.F.

    2015-01-01

    The f(R) gravity theories provide an alternative way to explain the current cosmic acceleration without invoking a dark energy matter component used in the cosmological modeling in the framework of general relativity. However, the freedom in the choice of the functional forms of f(R) gives rise to the problem of the degeneracy among these gravity theories on theoretical and (or) observational grounds. In this paper we examine the question as to whether the future dynamics can be used to break the degeneracy between f(R) gravity theories by investigating the dynamics of spatially homogeneous and isotropic dust flat models in two f(R) gravity theories, namely the well known f(R) = R+αR n gravity and another byAviles et al., whose motivation comes from the cosmographic approach to f(R) gravity. We perform a detailed numerical study of the dynamics of these theories taking into account the recent constraints on the cosmological parameters made by the Planck Collaboration. We demonstrate that besides being useful for discriminating between these two f(R) gravity theories, the future dynamics technique can also be used to determine the finite-time behavior as well as the fate of the Universe in the framework of these f(R) gravity theories. There also emerges from our analysis the result that one still can have a dust flat FLRWsolution with a big rip, if gravity is governed by f(R) = R+αR n . We also show that FLRW dust solutions with f'' < 0 do not necessarily lead to singularities. (orig.)

  5. 77 FR 48899 - Flutriafol; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2012-08-15

    ... Docket in the Environmental Protection Agency Docket Center (EPA/DC), located in EPA West, Rm. 3334, 1301... methodology (gas chromatography/Nitrogen/ Phosphorus detector (NPD) for tolerances and method ICIA AM00306 for...

  6. National Pesticide Information Center

    Science.gov (United States)

    ... How can I protect my pets when using pesticides around them? More FAQs FAQ Comics Video FAQs From NPIC: Fact Sheets Videos Web Apps Podcasts Outreach Materials NPIC Professional Resources Social Media: National Pesticide Information Center Tweets by NPICatOSU Please read our ...

  7. Galaxy-galaxy weak gravitational lensing in f(R) gravity

    Science.gov (United States)

    Li, Baojiu; Shirasaki, Masato

    2018-03-01

    We present an analysis of galaxy-galaxy weak gravitational lensing (GGL) in chameleon f(R) gravity - a leading candidate of non-standard gravity models. For the analysis, we have created mock galaxy catalogues based on dark matter haloes from two sets of numerical simulations, using a halo occupation distribution (HOD) prescription which allows a redshift dependence of galaxy number density. To make a fairer comparison between the f(R) and Λ cold dark matter (ΛCDM) models, their HOD parameters are tuned so that the galaxy two-point correlation functions in real space (and therefore the projected two-point correlation functions) match. While the f(R) model predicts an enhancement of the convergence power spectrum by up to ˜ 30 per cent compared to the standard ΛCDM model with the same parameters, the maximum enhancement of GGL is only half as large and less than 5 per cent on separations above ˜1-2 h-1 Mpc, because the latter is a cross-correlation of shear (or matter, which is more strongly affected by modified gravity) and galaxy (which is weakly affected given the good match between galaxy autocorrelations in the two models) fields. We also study the possibility of reconstructing the matter power spectrum by combination of GGL and galaxy clustering in f(R) gravity. We find that the galaxy-matter cross-correlation coefficient remains at unity down to ˜2-3 h-1 Mpc at relevant redshifts even in f(R) gravity, indicating joint analysis of GGL and galaxy clustering can be a powerful probe of matter density fluctuations in chameleon gravity. The scale dependence of the model differences in their predictions of GGL can potentially allows us to break the degeneracy between f(R) gravity and other cosmological parameters such as Ωm and σ8.

  8. 40 CFR 152.10 - Products that are not pesticides because they are not intended for a pesticidal purpose.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Products that are not pesticides because they are not intended for a pesticidal purpose. 152.10 Section 152.10 Protection of Environment... pesticidal purpose. A product that is not intended to prevent, destroy, repel, or mitigate a pest, or to...

  9. f(R) gravity solutions for evolving wormholes

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharya, Subhra [Presidency University, Department of Mathematics, Kolkata (India); Chakraborty, Subenoy [Jadavpur University, Department of Mathematics, Kolkata (India)

    2017-08-15

    The scalar-tensor f(R) theory of gravity is considered in the framework of a simple inhomogeneous space-time model. In this research we use the reconstruction technique to look for possible evolving wormhole solutions within viable f(R) gravity formalism. These f(R) models are then constrained so that they are consistent with existing experimental data. Energy conditions related to the matter threading the wormhole are analyzed graphically and are in general found to obey the null energy conditions (NEC) in regions around the throat, while in the limit f(R) = R, NEC can be violated at large in regions around the throat. (orig.)

  10. My Son 22.10.11

    Directory of Open Access Journals (Sweden)

    Rebecca Baillie

    2013-01-01

    Full Text Available 'My Son 22.10.11' was made immediately following a miscarriage 8 weeks into pregnancy. After bleeding lightly for a couple of hours, I went to the toilet and a large bloody mass fell from within me. I knew that I could not flush this away, and that to retrieve the mass was my only chance to connect with the unborn foetus. I fished the contents from the bottom of the toilet bowl using my hands and carried them into my small studio. I found some paper and began to dissect the mass. At the centre, I found the tiny, cold, hard foetus. I kissed it and then began to use it as a kind of painting tool, drawing the outline of the lost child using its very own flesh and blood. I knew that to create a lasting and tangible portrait of 'my son' was the best way to understand the somewhat unreal and fleeting experience of miscarriage. I thought of Frida Kahlo while making the work, thinking 'thank God' that I had a reference to miscarriage before it happened to me. I also thought of my childhood days spent on our family pig farm, and of all the dead pig foetuses that I had seen at various stages of development. Before the miscarriage, I thought little about the subject; afterwards, I recognise the profundity of the creation of a life that is never born. The experience is so common, yet so very rarely discussed or depicted.

  11. Exploring plane-symmetric solutions in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M. F., E-mail: farasat.shamir@nu.edu.pk [National University of Computer and Emerging Sciences, Department of Sciences and Humanities (Pakistan)

    2016-02-15

    The modified theories of gravity, especially the f(R) gravity, have attracted much attention in the last decade. This paper is devoted to exploring plane-symmetric solutions in the context of metric f(R) gravity. We extend the work on static plane-symmetric vacuum solutions in f(R) gravity already available in the literature [1, 2]. The modified field equations are solved using the assumptions of both constant and nonconstant scalar curvature. Some well-known solutions are recovered with power-law and logarithmic forms of f(R) models.

  12. Validity Generalization of the WISC-R Factor Structure with 10 1/2-Year-Old Children.

    Science.gov (United States)

    Shiek, David A.; Miller, John E.

    1978-01-01

    Investigated robustness of the Wechsler Intelligence Scale for Children-Revised (WISC-R) factor structure. Comparisons of the loadings obtained with generalization sample and 10 1/2-year-old national standardization sample suggest high degree of similarity in composition, magnitude, and pattern. Findings highly support robustness of WISC-R's…

  13. 12 CFR 563.146 - Will the OTS permit my capital distribution?

    Science.gov (United States)

    2010-01-01

    ... under 12 U.S.C. 1831o(d)(1)(B). (b) Your proposed capital distribution raises safety or soundness... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will the OTS permit my capital distribution... SAVINGS ASSOCIATIONS-OPERATIONS Capital Distributions § 563.146 Will the OTS permit my capital...

  14. Disentangling the f(R). Duality

    International Nuclear Information System (INIS)

    Broy, Benedict J.; Westphal, Alexander; Pedro, Francisco G.; Univ. Autonoma de Madrid

    2014-11-01

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R n with 1 2 -term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m 2 φ 2 -inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R 2 model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-l.

  15. Geodesic congruences in the Palatini f(R) theory

    International Nuclear Information System (INIS)

    Shojai, Fatimah; Shojai, Ali

    2008-01-01

    We shall investigate the properties of a congruence of geodesics in the framework of Palatini f(R) theories. We shall evaluate the modified geodesic deviation equation and the Raychaudhuri's equation and show that f(R) Palatini theories do not necessarily lead to attractive forces. Also, we shall study energy condition for f(R) Palatini gravity via a perturbative analysis of the Raychaudhuri's equation.

  16. Clustering of galaxies with f(R) gravity

    Science.gov (United States)

    Capozziello, Salvatore; Faizal, Mir; Hameeda, Mir; Pourhassan, Behnam; Salzano, Vincenzo; Upadhyay, Sudhaker

    2018-02-01

    Based on thermodynamics, we discuss the galactic clustering of expanding Universe by assuming the gravitational interaction through the modified Newton's potential given by f(R) gravity. We compute the corrected N-particle partition function analytically. The corrected partition function leads to more exact equations of state of the system. By assuming that the system follows quasi-equilibrium, we derive the exact distribution function that exhibits the f(R) correction. Moreover, we evaluate the critical temperature and discuss the stability of the system. We observe the effects of correction of f(R) gravity on the power-law behaviour of particle-particle correlation function also. In order to check the feasibility of an f(R) gravity approach to the clustering of galaxies, we compare our results with an observational galaxy cluster catalogue.

  17. Nonlinear evolution of f(R) cosmologies. I. Methodology

    International Nuclear Information System (INIS)

    Oyaizu, Hiroaki

    2008-01-01

    We introduce the method and the implementation of a cosmological simulation of a class of metric-variation f(R) models that accelerate the cosmological expansion without a cosmological constant and evade solar-system bounds of small-field deviations to general relativity. Such simulations are shown to reduce to solving a nonlinear Poisson equation for the scalar degree of freedom introduced by the f(R) modifications. We detail the method to efficiently solve the nonlinear Poisson equation by using a Newton-Gauss-Seidel relaxation scheme coupled with the multigrid method to accelerate the convergence. The simulations are shown to satisfy tests comparing the simulated outcome to analytical solutions for simple situations, and the dynamics of the simulations are tested with orbital and Zeldovich collapse tests. Finally, we present several static and dynamical simulations using realistic cosmological parameters to highlight the differences between standard physics and f(R) physics. In general, we find that the f(R) modifications result in stronger gravitational attraction that enhances the dark matter power spectrum by ∼20% for large but observationally allowed f(R) modifications. A more detailed study of the nonlinear f(R) effects on the power spectrum are presented in a companion paper.

  18. f(R) gravity and chameleon theories

    International Nuclear Information System (INIS)

    Brax, Philippe; Bruck, Carsten van de; Davis, Anne-Christine; Shaw, Douglas J.

    2008-01-01

    We analyze f(R) modifications of Einstein's gravity as dark energy models in the light of their connection with chameleon theories. Formulated as scalar-tensor theories, the f(R) theories imply the existence of a strong coupling of the scalar field to matter. This would violate all experimental gravitational tests on deviations from Newton's law. Fortunately, the existence of a matter dependent mass and a thin-shell effect allows one to alleviate these constraints. The thin-shell condition also implies strong restrictions on the cosmological dynamics of the f(R) theories. As a consequence, we find that the equation of state of dark energy is constrained to be extremely close to -1 in the recent past. We also examine the potential effects of f(R) theories in the context of the Eoet-wash experiments. We show that the requirement of a thin shell for the test bodies is not enough to guarantee a null result on deviations from Newton's law. As long as dark energy accounts for a sizeable fraction of the total energy density of the Universe, the constraints that we deduce also forbid any measurable deviation of the dark energy equation of state from -1. All in all, we find that both cosmological and laboratory tests imply that f(R) models are almost coincident with a ΛCDM model at the background level.

  19. Stellar equilibrium configurations of white dwarfs in the f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, G.A.; Moraes, P.H.R.S.; Marinho, R.M.; Malheiro, M. [Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, SP (Brazil); Lobato, R.V. [Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, SP (Brazil); Sapienza Universita di Roma, Dipartimento di Fisica, Rome (Italy); ICRANet, Pescara (Italy); Arbanil, Jose D.V. [Universidad Privada del Norte, Departamento de Ciencias, Lima (Peru); Otoniel, E. [Universidade Federal do Cariri, Instituto de Formacao de Professores, Brejo Santo, CE (Brazil)

    2017-12-15

    In this work we investigate the equilibrium configurations of white dwarfs in a modified gravity theory, namely, f(R, T) gravity, for which R and T stand for the Ricci scalar and trace of the energy-momentum tensor, respectively. Considering the functional form f(R, T) = R+2λT, with λ being a constant, we obtain the hydrostatic equilibrium equation for the theory. Some physical properties of white dwarfs, such as: mass, radius, pressure and energy density, as well as their dependence on the parameter λ are derived. More massive and larger white dwarfs are found for negative values of λ when it decreases. The equilibrium configurations predict a maximum mass limit for white dwarfs slightly above the Chandrasekhar limit, with larger radii and lower central densities when compared to standard gravity outcomes. The most important effect of f(R, T) theory for massive white dwarfs is the increase of the radius in comparison with GR and also f(R) results. By comparing our results with some observational data of massive white dwarfs we also find a lower limit for λ, namely, λ > -3 x 10{sup -4}. (orig.)

  20. Dynamics of anisotropic power-law f(R) cosmology

    International Nuclear Information System (INIS)

    Shamir, M. F.

    2016-01-01

    Modified theories of gravity have attracted much attention of the researchers in the recent years. In particular, the f(R) theory has been investigated extensively due to important f(R) gravity models in cosmological contexts. This paper is devoted to exploring an anisotropic universe in metric f(R) gravity. A locally rotationally symmetric Bianchi type I cosmological model is considered for this purpose. Exact solutions of modified field equations are obtained for a well-known f(R) gravity model. The energy conditions are also discussed for the model under consideration. The viability of the model is investigated via graphical analysis using the present-day values of cosmological parameters. The model satisfies null energy, weak energy, and dominant energy conditions for a particular range of the anisotropy parameter while the strong energy condition is violated, which shows that the anisotropic universe in f(R) gravity supports the crucial issue of accelerated expansion of the universe.

  1. Dynamics of anisotropic power-law f(R) cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M. F., E-mail: farasat.shamir@nu.edu.pk [National University of Computer and Emerging Sciences, Lahore Campus, Department of Sciences and Humanities (Pakistan)

    2016-12-15

    Modified theories of gravity have attracted much attention of the researchers in the recent years. In particular, the f(R) theory has been investigated extensively due to important f(R) gravity models in cosmological contexts. This paper is devoted to exploring an anisotropic universe in metric f(R) gravity. A locally rotationally symmetric Bianchi type I cosmological model is considered for this purpose. Exact solutions of modified field equations are obtained for a well-known f(R) gravity model. The energy conditions are also discussed for the model under consideration. The viability of the model is investigated via graphical analysis using the present-day values of cosmological parameters. The model satisfies null energy, weak energy, and dominant energy conditions for a particular range of the anisotropy parameter while the strong energy condition is violated, which shows that the anisotropic universe in f(R) gravity supports the crucial issue of accelerated expansion of the universe.

  2. Effects of currently used pesticides in the AhR-CALUX assay

    DEFF Research Database (Denmark)

    Long, Manhai; Laier, Peter; Vinggaard, Anne Marie

    2003-01-01

    101L hepatoma cell lines. In comparison the results indicated that the rat H4IIE cell line is more sensitive than the human TV101L for detection of TCDD inducing AhR-CALUX activity. The pesticides iprodione, chlorpyrifos and prochloraz showed dose-dependent AhR agonistic effects in both cell lines...

  3. Cosmology of f(R) gravity in the metric variational approach

    Science.gov (United States)

    Li, Baojiu; Barrow, John D.

    2007-04-01

    We consider the cosmologies that arise in a subclass of f(R) gravity with f(R)=R+μ2n+2/(-R)n and n∈(-1,0) in the metric (as opposed to the Palatini) variational approach to deriving the gravitational field equations. The calculations of the isotropic and homogeneous cosmological models are undertaken in the Jordan frame and at both the background and the perturbation levels. For the former, we also discuss the connection to the Einstein frame in which the extra degree of freedom in the theory is associated with a scalar field sharing some of the properties of a “chameleon” field. For the latter, we derive the cosmological perturbation equations in general theories of f(R) gravity in covariant form and implement them numerically to calculate the cosmic microwave background (CMB) temperature and matter power spectra of the cosmological model. The CMB power is shown to reduce at low l’s, and the matter power spectrum is almost scale independent at small scales, thus having a similar shape to that in standard general relativity. These are in stark contrast with what was found in the Palatini f(R) gravity, where the CMB power is largely amplified at low l’s and the matter spectrum is strongly scale dependent at small scales. These features make the present model more adaptable than that arising from the Palatini f(R) field equations, and none of the data on background evolution, CMB power spectrum, or matter power spectrum currently rule it out.

  4. Further stable neutron star models from f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Astashenok, Artyom V. [I. Kant Baltic Federal University, Institute of Physics and Technology, Nevskogo st. 14, Kaliningrad, 236041 (Russian Federation); Capozziello, Salvatore [Dipartimento di Fisica, Università di Napoli ' ' Federico II' ' , Via Cinthia, 9, Napoli, I–80126 (Italy); Odintsov, Sergei D., E-mail: artyom.art@gmail.com, E-mail: capozziello@na.infn.it, E-mail: odintsov@ieec.uab.es [Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona (Spain)

    2013-12-01

    Neutron star models in perturbative f(R) gravity are considered with realistic equations of state. In particular, we consider the FPS, SLy and other equations of state and a case of piecewise equation of state for stars with quark cores. The mass-radius relations for f(R) = R+R(e{sup −R/R{sub 0}}−1) model and for R{sup 2} models with logarithmic and cubic corrections are obtained. In the case of R{sup 2} gravity with cubic corrections, we obtain that at high central densities (ρ > 10ρ{sub ns}, where ρ{sub ns} = 2.7 × 10{sup 14} g/cm{sup 3} is the nuclear saturation density), stable star configurations exist. The minimal radius of such stars is close to 9 km with maximal mass ∼ 1.9M{sub ⊙} (SLy equation). A similar situation takes place for AP4 and BSK20 EoS. Such an effect can give rise to more compact stars than in General Relativity. If observationally identified, such objects could constitute a formidable signature for modified gravity at astrophysical level. Another interesting result can be achieved in modified gravity with only a cubic correction. For some EoS, the upper limit of neutron star mass increases and therefore these EoS can describe realistic star configurations (although, in General Relativity, these EoS are excluded by observational constraints)

  5. Further stable neutron star models from f(R) gravity

    International Nuclear Information System (INIS)

    Astashenok, Artyom V.; Capozziello, Salvatore; Odintsov, Sergei D.

    2013-01-01

    Neutron star models in perturbative f(R) gravity are considered with realistic equations of state. In particular, we consider the FPS, SLy and other equations of state and a case of piecewise equation of state for stars with quark cores. The mass-radius relations for f(R) = R+R(e −R/R 0 −1) model and for R 2 models with logarithmic and cubic corrections are obtained. In the case of R 2 gravity with cubic corrections, we obtain that at high central densities (ρ > 10ρ ns , where ρ ns = 2.7 × 10 14 g/cm 3 is the nuclear saturation density), stable star configurations exist. The minimal radius of such stars is close to 9 km with maximal mass ∼ 1.9M ⊙ (SLy equation). A similar situation takes place for AP4 and BSK20 EoS. Such an effect can give rise to more compact stars than in General Relativity. If observationally identified, such objects could constitute a formidable signature for modified gravity at astrophysical level. Another interesting result can be achieved in modified gravity with only a cubic correction. For some EoS, the upper limit of neutron star mass increases and therefore these EoS can describe realistic star configurations (although, in General Relativity, these EoS are excluded by observational constraints)

  6. Closed string tachyon driving f(R) cosmology

    Science.gov (United States)

    Wang, Peng; Wu, Houwen; Yang, Haitang

    2018-05-01

    To study quantum effects on the bulk tachyon dynamics, we replace R with f(R) in the low-energy effective action that couples gravity, the dilaton, and the bulk closed string tachyon of bosonic closed string theory and study properties of their classical solutions. The α' corrections of the graviton-dilaton-tachyon system are implemented in the f(R). We obtain the tachyon-induced rolling solutions and show that the string metric does not need to remain fixed in some cases. In the case with H( t=‑∞ ) = , only the R and R2 terms in f(R) play a role in obtaining the rolling solutions with nontrivial metric. The singular behavior of more classical solutions are investigated and found to be modified by quantum effects. In particular, there could exist some classical solutions, in which the tachyon field rolls down from a maximum of the tachyon potential while the dilaton expectation value is always bounded from above during the rolling process.

  7. f(R) gravity, torsion and non-metricity

    International Nuclear Information System (INIS)

    Sotiriou, Thomas P

    2009-01-01

    For both f(R) theories of gravity with an independent symmetric connection (no torsion), usually referred to as Palatini f(R) gravity theories, and for f(R) theories of gravity with torsion but no non-metricity, called U4 theories, it has been shown that the independent connection can actually be eliminated algebraically, as long as this connection does not couple to matter. Remarkably, the outcome in both cases is the same theory, which is dynamically equivalent with an ω 0 = -3/2 Brans-Dicke theory. It is shown here that even for the most general case of an independent connection with both non-metricity and torsion, one arrives at exactly the same theory as in the more restricted cases. This generalizes the previous results and explains why assuming that either the torsion or the non-metricity vanishing ultimately leads to the same theory. It also demonstrates that f(R) actions cannot support an independent connection which carries dynamical degrees of freedom, irrespective of how general this connection is, at least as long as there is no connection-matter coupling. (fast track communication)

  8. Standard cosmological evolution in the f(R) model to Kaluza-Klein cosmology

    International Nuclear Information System (INIS)

    Aghmohammadi, A; Abolhassani, M R; Saaidi, Kh; Vajdi, A

    2009-01-01

    In this paper, using f(R) theory of gravity we explicitly calculate cosmological evolution in the presence of a perfect fluid source in four- and five-dimensional space-time in which this cosmological evolution in self-creation is presented by Reddy et al (2009 Int. J. Theor. Phys. 48 10). An exact cosmological model is presented using a relation between Einstein's gravity field equation components due to a metric with the same component from f(R) theory of gravity. Some physics and kinematical properties of the model are also discussed.

  9. Effective Dark Matter Halo Catalog in f(R) Gravity.

    Science.gov (United States)

    He, Jian-Hua; Hawken, Adam J; Li, Baojiu; Guzzo, Luigi

    2015-08-14

    We introduce the idea of an effective dark matter halo catalog in f(R) gravity, which is built using the effective density field. Using a suite of high resolution N-body simulations, we find that the dynamical properties of halos, such as the distribution of density, velocity dispersion, specific angular momentum and spin, in the effective catalog of f(R) gravity closely mimic those in the cold dark matter model with a cosmological constant (ΛCDM). Thus, when using effective halos, an f(R) model can be viewed as a ΛCDM model. This effective catalog therefore provides a convenient way for studying the baryonic physics, the galaxy halo occupation distribution and even semianalytical galaxy formation in f(R) cosmologies.

  10. Constraints on perturbative f(R) gravity via neutron stars

    Energy Technology Data Exchange (ETDEWEB)

    Arapoğlu, Savaş; Ekşi, K. Yavuz [İstanbul Technical University, Faculty of Science and Letters, Physics Engineering Department, Maslak 34469, İstanbul (Turkey); Deliduman, Cemsinan, E-mail: arapoglu@itu.edu.tr, E-mail: cemsinan@msgsu.edu.tr, E-mail: eksi@itu.edu.tr [Mimar Sinan Fine Arts University, Department of Physics, Beşiktaş 34349, İstanbul (Turkey)

    2011-07-01

    We study the structure of neutron stars in perturbative f(R) gravity models with realistic equations of state. We obtain mass-radius relations in a gravity model of the form f(R) = R+αR{sup 2}. We find that deviations from the results of general relativity, comparable to the variations due to using different equations of state (EoS'), are induced for |α| ∼ 10{sup 9} cm{sup 2}. Some of the soft EoS' that are excluded within the framework of general relativity can be reconciled with the 2 solar mass neutron star recently observed for certain values of α within this range. For some of the EoS' we find that a new solution branch, which allows highly massive neutron stars, exists for values of α greater than a few 10{sup 9} cm{sup 2}. We find constraints on α for a variety of EoS' using the recent observational constraints on the mass-radius relation. These are all 5 orders of magnitude smaller than the recent constraint obtained via Gravity Probe B for this gravity model. The associated length scale √(alpha)approx 10{sup 5} cm is only an order of magnitude smaller than the typical radius of a neutron star, the probe used in this test. This implies that real deviations from general relativity can be even smaller.

  11. Wormholes in R{sup 2}-gravity within the f(R, T) formalism

    Energy Technology Data Exchange (ETDEWEB)

    Sahoo, P.K.; Sahoo, Parbati [Birla Institute of Technology and Science-Pilani, Department of Mathematics, Hyderabad (India); Moraes, P.H.R.S. [ITA-Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, Sao Paulo (Brazil)

    2018-01-15

    We propose, as a novelty in the literature, the modeling of wormholes within a particular case of f(R, T) gravity, namely f(R, T) = R + αR{sup 2} + λT, with R and T being the Ricci scalar and trace of the energy-momentum tensor, respectively, while α and λ are constants. Although such a functional form application can be found in the literature, those concern compact astrophysical objects, such that no wormhole analysis has been done so far. The quadratic geometric and linear material corrections of this theory render the matter content of the wormhole remarkably able to obey the energy conditions. (orig.)

  12. Existence of relativistic stars in f(R) gravity

    International Nuclear Information System (INIS)

    Upadhye, Amol; Hu, Wayne

    2009-01-01

    We refute recent claims in the literature that stars with relativistically deep potentials cannot exist in f(R) gravity. Numerical examples of stable stars, including relativistic (GM * /r * ∼0.1), constant density stars, are studied. As a star is made larger, nonlinear 'chameleon' effects screen much of the star's mass, stabilizing gravity at the stellar center. Furthermore, we show that the onset of this chameleon screening is unrelated to strong gravity. At large central pressures P>ρ/3, f(R) gravity, like general relativity, does have a maximum gravitational potential, but at a slightly smaller value: GM * /r * | max =0.345<4/9 for constant density and one choice of parameters. This difference is associated with negative central curvature R under general relativity not being accessed in the f(R) model, but does not apply to any known astrophysical object.

  13. f(R) gravity: scalar perturbations in the late Universe

    Czech Academy of Sciences Publication Activity Database

    Eingorn, M.; Novák, Jan; Zhuk, A.

    2014-01-01

    Roč. 74, č. 8 (2014), s. 3005 ISSN 1434-6044 Institutional support: RVO:67985840 Keywords : nonlinear f(R) gravity * scalar cosmological perturbations * scalaron Subject RIV: BA - General Mathematics Impact factor: 5.084, year: 2014 http://link.springer.com/article/10.1140/epjc/s10052-014-3005-1

  14. Models of f(R) cosmic acceleration that evade solar system tests

    International Nuclear Information System (INIS)

    Hu, Wayne; Sawicki, Ignacy

    2007-01-01

    We study a class of metric-variation f(R) models that accelerates the expansion without a cosmological constant and satisfies both cosmological and solar-system tests in the small-field limit of the parameter space. Solar-system tests alone place only weak bounds on these models, since the additional scalar degree of freedom is locked to the high-curvature general-relativistic prediction across more than 25 orders of magnitude in density, out through the solar corona. This agreement requires that the galactic halo be of sufficient extent to maintain the galaxy at high curvature in the presence of the low-curvature cosmological background. If the galactic halo and local environment in f(R) models do not have substantially deeper potentials than expected in ΛCDM, then cosmological field amplitudes |f R | > or approx.10 -6 will cause the galactic interior to evolve to low curvature during the acceleration epoch. Viability of large-deviation models therefore rests on the structure and evolution of the galactic halo, requiring cosmological simulations of f(R) models, and not directly on solar-system tests. Even small deviations that conservatively satisfy both galactic and solar-system constraints can still be tested by future, percent-level measurements of the linear power spectrum, while they remain undetectable to cosmological-distance measures. Although we illustrate these effects in a specific class of models, the requirements on f(R) are phrased in a nearly model-independent manner

  15. f(R) gravity cosmology in scalar degree of freedom

    International Nuclear Information System (INIS)

    Goswami, Umananda Dev; Deka, Kabita

    2014-01-01

    The models of f(R) gravity belong to an important class of modified gravity models where the late time cosmic accelerated expansion is considered as the manifestation of the large scale modification of the force of gravity. f(R) gravity models can be expressed in terms of a scalar degree of freedom by explicit redefinition of model's variable. Here we report about the study of the features of cosmological parameters and hence the cosmological evolution using the scalar degree of freedom of the f(R) = ξR n gravity model in the Friedmann-Lemaître-Robertson-Walker (FLRW) background

  16. Constraint propagation equations of the 3+1 decomposition of f(R) gravity

    International Nuclear Information System (INIS)

    Paschalidis, Vasileios; Shapiro, Stuart L; Halataei, Seyyed M H; Sawicki, Ignacy

    2011-01-01

    Theories of gravity other than general relativity (GR) can explain the observed cosmic acceleration without a cosmological constant. One such class of theories of gravity is f(R). Metric f(R) theories have been proven to be equivalent to Brans-Dicke (BD) scalar-tensor gravity without a kinetic term (ω = 0). Using this equivalence and a 3+1 decomposition of the theory, it has been shown that metric f(R) gravity admits a well-posed initial value problem. However, it has not been proven that the 3+1 evolution equations of metric f(R) gravity preserve the (Hamiltonian and momentum) constraints. In this paper, we show that this is indeed the case. In addition, we show that the mathematical form of the constraint propagation equations in BD-equilavent f(R) gravity and in f(R) gravity in both the Jordan and Einstein frames is exactly the same as in the standard ADM 3+1 decomposition of GR. Finally, we point out that current numerical relativity codes can incorporate the 3+1 evolution equations of metric f(R) gravity by modifying the stress-energy tensor and adding an additional scalar field evolution equation. We hope that this work will serve as a starting point for relativists to develop fully dynamical codes for valid f(R) models.

  17. Pulsmätning och stegräkning från Android Wear : Utveckling av en applikation för att spara mätdata

    OpenAIRE

    Lund, Fredrik

    2016-01-01

    Detta examensarbete beskriver utvecklingen av en applikation för att överföra data från en Android Wear smartklocka till en Android smarttelefon som sedan skickar datan vidare till en server. Servern sätter in datan i en MySQL-databas. Android Wear smartklockornas sensorer undersöks även. Smartklockorna har sensorer för stegräkning och pulsmätning. I examensarbetet beskrivs det hur sensorerna fungerar. Därtill genomgås Androids historia i korta drag samt basfunktionerna i Android operativsyst...

  18. Robust approach to f(R) gravity

    International Nuclear Information System (INIS)

    Jaime, Luisa G.; Patino, Leonardo; Salgado, Marcelo

    2011-01-01

    We consider metric f(R) theories of gravity without mapping them to their scalar-tensor counterpart, but using the Ricci scalar itself as an ''extra'' degree of freedom. This approach avoids then the introduction of a scalar-field potential that might be ill defined (not single valued). In order to explicitly show the usefulness of this method, we focus on static and spherically symmetric spacetimes and deal with the recent controversy about the existence of extended relativistic objects in certain class of f(R) models.

  19. 75 FR 16105 - Dicloran; Cancellation Order for Amendment to Terminate a Use of DCNA Pesticide Registrations

    Science.gov (United States)

    2010-03-31

    ... identified in Table 1 in Unit II. in a manner inconsistent with any of the Provisions for Disposition of... for pesticide registrations listed in Table 1 in Unit II. pursuant to section 6(f)(1) of the Federal..., 2009 (74 FR 63151) Federal Register Notice of Receipt of Request from the registrant listed in Table 2...

  20. Possible antigravity regions in F(R) theory?

    Energy Technology Data Exchange (ETDEWEB)

    Bamba, Kazuharu, E-mail: bamba@kmi.nagoya-u.ac.jp [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Nojiri, Shin' ichi, E-mail: nojiri@phys.nagoya-u.ac.jp [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Odintsov, Sergei D., E-mail: odintsov@ieec.uab.es [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona (Spain); Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C5-Par-2a pl, E-08193 Bellaterra (Barcelona) (Spain); Tomsk State Pedagogical University, Kievskaya Avenue, 60, 634061, Tomsk (Russian Federation); Sáez-Gómez, Diego, E-mail: diego.saezgomez@uct.ac.za [Astrophysics, Cosmology and Gravity Centre (ACGC) and Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701, Cape Town (South Africa); Fisika Teorikoaren eta Zientziaren Historia Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, 644 Posta Kutxatila, 48080 Bilbao (Spain)

    2014-03-07

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  1. Holographic dark energy and f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Aghamohammadi, A [Faculty of Science, Islamic Azad University of Sanandaj, Sanandaj (Iran, Islamic Republic of); Saaidi, Kh, E-mail: ksaaidi@uok.ac.ir, E-mail: agha35484@yahoo.com [Department of Physics, Faculty of Science, University of Kurdistan, Sanandaj (Iran, Islamic Republic of)

    2011-02-15

    We investigate the corresponding relation between f(R) gravity and holographic dark energy. We introduce a type of energy density from f(R) that has the same role as holographic dark energy. We obtain the differential equation that specifies the evolution of the introduced energy density parameter based on a varying gravitational constant. We discover the relation for the equation of state parameter for low redshifts that contains varying G correction.

  2. Possible antigravity regions in F(R) theory?

    Science.gov (United States)

    Bamba, Kazuharu; Nojiri, Shin'ichi; Odintsov, Sergei D.; Sáez-Gómez, Diego

    2014-03-01

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  3. Possible antigravity regions in F(R) theory?

    International Nuclear Information System (INIS)

    Bamba, Kazuharu; Nojiri, Shin'ichi; Odintsov, Sergei D.; Sáez-Gómez, Diego

    2014-01-01

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  4. f(R) constant-roll inflation

    Energy Technology Data Exchange (ETDEWEB)

    Motohashi, Hayato [Universidad de Valencia-CSIC, Instituto de Fisica Corpuscular (IFIC), Valencia (Spain); Starobinsky, Alexei A. [L.D. Landau Institute for Theoretical Physics, RAS, Moscow (Russian Federation); National Research University Higher School of Economics, Moscow (Russian Federation)

    2017-08-15

    The previously introduced class of two-parametric phenomenological inflationary models in general relativity in which the slow-roll assumption is replaced by the more general, constant-roll condition is generalized to the case of f(R) gravity. A simple constant-roll condition is defined in the original Jordan frame, and exact expressions for a scalaron potential in the Einstein frame, for a function f(R) (in the parametric form) and for inflationary dynamics are obtained. The region of the model parameters permitted by the latest observational constraints on the scalar spectral index and the tensor-to-scalar ratio of primordial metric perturbations generated during inflation is determined. (orig.)

  5. 77 FR 1656 - Proposed Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, R...

    Science.gov (United States)

    2012-01-11

    ...-0117; Airspace Docket No. 09-AGL-31] RIN 2120-AI92 Proposed Establishment of Restricted Areas R-5402, R-5403A, R- 5403B, R-5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND AGENCY: Federal Aviation... Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND (76 FR 72869...

  6. 12 CFR 516.80 - What language must I use in my publication?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What language must I use in my publication? 516.80 Section 516.80 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Publication Requirements § 516.80 What language must I use in my publication...

  7. 41 CFR 302-10.206 - May my agency assume direct responsibility for the costs of preparing and transporting my mobile...

    Science.gov (United States)

    2010-07-01

    ... direct responsibility for the costs of preparing and transporting my mobile home? 302-10.206 Section 302... ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 10-ALLOWANCES FOR TRANSPORTATION OF MOBILE HOMES AND BOATS... responsibility for the costs of preparing and transporting my mobile home? Yes, your agency may assume direct...

  8. Cosmological reconstruction of realistic modified F(R) gravities

    International Nuclear Information System (INIS)

    Nojiri, Shin'ichi; Odintsov, Sergei D.; Saez-Gomez, Diego

    2009-01-01

    The cosmological reconstruction scheme for modified F(R) gravity is developed in terms of e-folding (or, redshift). It is demonstrated how any FRW cosmology may emerge from specific F(R) theory. The specific examples of well-known cosmological evolution are reconstructed, including ΛCDM cosmology, deceleration with transition to phantom superacceleration era which may develop singularity or be transient. The application of this scheme to viable F(R) gravities unifying inflation with dark energy era is proposed. The additional reconstruction of such models leads to non-leading gravitational correction mainly relevant at the early/late universe and helping to pass the cosmological bounds (if necessary). It is also shown how cosmological reconstruction scheme may be generalized in the presence of scalar field.

  9. Developmental neurotoxicity of different pesticides in PC-12 cells in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Christen, Verena [University of Applied Sciences and Arts Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH-4132, Muttenz (Switzerland); Rusconi, Manuel; Crettaz, Pierre [Federal Office of Public Health, Division Chemical Products, 3003 Bern (Switzerland); Fent, Karl, E-mail: karl.fent@bluewin.ch [University of Applied Sciences and Arts Northwestern Switzerland, School of Life Sciences, Gründenstrasse 40, CH-4132, Muttenz (Switzerland); Swiss Federal Institute of Technology Zürich (ETH Zürich), Department of Environmental Systems Sciences, Institute of Biogeochemistry and Pollution Dynamics, CH-8092 Zürich (Switzerland)

    2017-06-15

    The detection of developmental neurotoxicity (DNT) of chemicals has high relevance for protection of human health. However, DNT of many pesticides is only little known. Furthermore, validated in vitro systems for assessment of DNT are not well established. Here we employed the rat phaeochromocytoma cell line PC-12 to evaluate DNT of 18 frequently used pesticides of different classes, including neonicotinoids, pyrethroids, organophosphates, organochlorines, as well as quaternary ammonium compounds, the organic compound used in pesticides, piperonyl butoxide, as well as the insect repellent diethyltoluamide (DEET). We determined the outgrowth of neurites in PC-12 cells co-treated with nerve growth factor and different concentrations of biocides for 5 days. Furthermore, we determined transcriptional alterations of selected genes that may be associated with DNT, such as camk2α and camk2β, gap-43, neurofilament-h, tubulin-α and tubulin-β. Strong and dose- dependent inhibition of neurite outgrowth was induced by azamethiphos and chlorpyrifos, and dieldrin and heptachlor, which was correlated with up-regulation of gap-43. No or only weak effects on neurite outgrowth and transcriptional alterations occurred for neonicotinoids acetamiprid, clothianidin, imidacloprid and thiamethoxam, the pyrethroids λ-cyhalothrin, cyfluthrin, deltamethrin, and permethrin, the biocidal disinfectants C12-C14-alkyl(ethylbenzyl)dimethylammonium (BAC), benzalkonium chloride and barquat (dimethyl benzyl ammonium chloride), and piperonyl butoxide and DEET. Our study confirms potential developmental neurotoxicity of some pesticides and provides first evidence that azamethiphos has the potential to act as a developmental neurotoxic compound. We also demonstrate that inhibition of neurite outgrowth and transcriptional alterations of gap-43 expression correlate, which suggests the employment of gap-43 expression as a biomarker for detection and initial evaluation of potential DNT of chemicals

  10. Developmental neurotoxicity of different pesticides in PC-12 cells in vitro

    International Nuclear Information System (INIS)

    Christen, Verena; Rusconi, Manuel; Crettaz, Pierre; Fent, Karl

    2017-01-01

    The detection of developmental neurotoxicity (DNT) of chemicals has high relevance for protection of human health. However, DNT of many pesticides is only little known. Furthermore, validated in vitro systems for assessment of DNT are not well established. Here we employed the rat phaeochromocytoma cell line PC-12 to evaluate DNT of 18 frequently used pesticides of different classes, including neonicotinoids, pyrethroids, organophosphates, organochlorines, as well as quaternary ammonium compounds, the organic compound used in pesticides, piperonyl butoxide, as well as the insect repellent diethyltoluamide (DEET). We determined the outgrowth of neurites in PC-12 cells co-treated with nerve growth factor and different concentrations of biocides for 5 days. Furthermore, we determined transcriptional alterations of selected genes that may be associated with DNT, such as camk2α and camk2β, gap-43, neurofilament-h, tubulin-α and tubulin-β. Strong and dose- dependent inhibition of neurite outgrowth was induced by azamethiphos and chlorpyrifos, and dieldrin and heptachlor, which was correlated with up-regulation of gap-43. No or only weak effects on neurite outgrowth and transcriptional alterations occurred for neonicotinoids acetamiprid, clothianidin, imidacloprid and thiamethoxam, the pyrethroids λ-cyhalothrin, cyfluthrin, deltamethrin, and permethrin, the biocidal disinfectants C12-C14-alkyl(ethylbenzyl)dimethylammonium (BAC), benzalkonium chloride and barquat (dimethyl benzyl ammonium chloride), and piperonyl butoxide and DEET. Our study confirms potential developmental neurotoxicity of some pesticides and provides first evidence that azamethiphos has the potential to act as a developmental neurotoxic compound. We also demonstrate that inhibition of neurite outgrowth and transcriptional alterations of gap-43 expression correlate, which suggests the employment of gap-43 expression as a biomarker for detection and initial evaluation of potential DNT of chemicals

  11. Developmental neurotoxicity of different pesticides in PC-12 cells in vitro.

    Science.gov (United States)

    Christen, Verena; Rusconi, Manuel; Crettaz, Pierre; Fent, Karl

    2017-06-15

    The detection of developmental neurotoxicity (DNT) of chemicals has high relevance for protection of human health. However, DNT of many pesticides is only little known. Furthermore, validated in vitro systems for assessment of DNT are not well established. Here we employed the rat phaeochromocytoma cell line PC-12 to evaluate DNT of 18 frequently used pesticides of different classes, including neonicotinoids, pyrethroids, organophosphates, organochlorines, as well as quaternary ammonium compounds, the organic compound used in pesticides, piperonyl butoxide, as well as the insect repellent diethyltoluamide (DEET). We determined the outgrowth of neurites in PC-12 cells co-treated with nerve growth factor and different concentrations of biocides for 5days. Furthermore, we determined transcriptional alterations of selected genes that may be associated with DNT, such as camk2α and camk2β, gap-43, neurofilament-h, tubulin-α and tubulin-β. Strong and dose- dependent inhibition of neurite outgrowth was induced by azamethiphos and chlorpyrifos, and dieldrin and heptachlor, which was correlated with up-regulation of gap-43. No or only weak effects on neurite outgrowth and transcriptional alterations occurred for neonicotinoids acetamiprid, clothianidin, imidacloprid and thiamethoxam, the pyrethroids λ-cyhalothrin, cyfluthrin, deltamethrin, and permethrin, the biocidal disinfectants C12-C14-alkyl(ethylbenzyl)dimethylammonium (BAC), benzalkonium chloride and barquat (dimethyl benzyl ammonium chloride), and piperonyl butoxide and DEET. Our study confirms potential developmental neurotoxicity of some pesticides and provides first evidence that azamethiphos has the potential to act as a developmental neurotoxic compound. We also demonstrate that inhibition of neurite outgrowth and transcriptional alterations of gap-43 expression correlate, which suggests the employment of gap-43 expression as a biomarker for detection and initial evaluation of potential DNT of chemicals

  12. Retraction: Adyel et al. Health Risk Assessment of Pesticide Residues via Dietary Intake of Market Vegetables from Dhaka, Bangladesh. Foods 2013, 2, 64–75

    Directory of Open Access Journals (Sweden)

    Md. Shakhaoat Hossain

    2013-07-01

    Full Text Available The following article [1], doi: 10.3390/foods2010064, website: http://www.mdpi.com/2304-8158/2/1/64, has been retracted by the authors because of some major errors in broad field of pesticide residues identification and concentrations. During random cross check retention time of pesticides by HPLC did not match with the standards of detected pesticides. As a result concentration of all detected pesticides, maximum residue limits (MRLs and health risk assessments were changed. All these errors made the article [1] as a wrong one. All authors have confirmed that the reported results produced using quite inappropriate procedures. As first author herein, I take full responsibility for the retraction of our experiments and any other errors in its contents, and would like to offer my apologies on behalf of my co-authors to the readership of Foods for any inconveniences caused by this retraction.

  13. Cosmology of Horava-Lifshitz f(R) gravity

    International Nuclear Information System (INIS)

    Chakrabarti, Sayan K.; Sen, Anjan A.

    2011-08-01

    We discuss the cosmology of recently proposed Horava-Lifshitz f(R) gravity. In particular, we derive the modified Hubble equation that reduces to the standard HL gravity case in appropriate limit. We show how the bounce solutions in this theory are modified due to nonlinear effect of f(R) gravity. In addition we find that the solutions exist when the Universe can make turn around for large scale-factor. Therefore, in principle, the Universe in this set-up can show cyclic behavior. (orig.)

  14. Cosmology of Horava-Lifshitz f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Chakrabarti, Sayan K. [Univ. Tecnica de Lisboa (Portugal). Inst. Superior Tecnico; Dutta, Koushik [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Sen, Anjan A. [Centre of Theoretical Physics, Jamia Millia Islamia, New Dehli (India)

    2011-08-15

    We discuss the cosmology of recently proposed Horava-Lifshitz f(R) gravity. In particular, we derive the modified Hubble equation that reduces to the standard HL gravity case in appropriate limit. We show how the bounce solutions in this theory are modified due to nonlinear effect of f(R) gravity. In addition we find that the solutions exist when the Universe can make turn around for large scale-factor. Therefore, in principle, the Universe in this set-up can show cyclic behavior. (orig.)

  15. Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease.

    Science.gov (United States)

    Xavier, Joana M; Shahram, Farhad; Davatchi, Fereydoun; Rosa, Alexandra; Crespo, Jorge; Abdollahi, Bahar Sadeghi; Nadji, Abdolhadi; Jesus, Gorete; Barcelos, Filipe; Patto, José Vaz; Shafiee, Niloofar Mojarad; Ghaderibarim, Fahmida; Oliveira, Sofia A

    2012-08-01

    Independent replication of the findings from genome-wide association studies (GWAS) remains the gold standard for results validation. Our aim was to test the association of Behçet's disease (BD) with the interleukin-10 gene (IL10) and the IL-23 receptor-IL-12 receptor β2 (IL23R-IL12RB2) locus, each of which has been previously identified as a risk factor for BD in 2 different GWAS. Six haplotype-tagging single-nucleotide polymorphisms (SNPs) in IL10 and 42 in IL23R-IL12RB2 were genotyped in 973 Iranian patients with BD and 637 non-BD controls. Population stratification was assessed using a panel of 86 ancestry-informative markers. Subtle evidence of population stratification was found in our data set. In IL10, rs1518111 was nominally associated with BD before and after adjustment for population stratification (odds ratio [OR] for T allele 1.20, 95% confidence interval [95% CI] 1.02-1.40, unadjusted P [P(unadj) ] = 2.53 × 10(-2) ; adjusted P [P(adj) ] = 1.43 × 10(-2) ), and rs1554286 demonstrated a trend toward association (P(unadj) = 6.14 × 10(-2) ; P(adj) = 3.21 × 10(-2) ). Six SNPs in IL23R-IL12RB2 were found to be associated with BD after Bonferroni correction for multiple testing, the most significant of which were rs17375018 (OR for G allele 1.51, 95% CI 1.27-1.78, P(unadj) = 1.93 × 10(-6) ), rs7517847 (OR for T allele 1.48, 95% CI 1.26-1.74, P(unadj) = 1.23 × 10(-6) ), and rs924080 (OR for T allele 1.29, 95% CI 1.20-1.39, P = 1.78 × 10(-5) ). SNPs rs10489629, rs1343151, and rs1495965 were also significantly associated with BD in all tests performed. Results of meta-analyses of our data combined with data from other populations further confirmed the role of rs1518111, rs17375018, rs7517847, and rs924080 in the risk of BD, but no epistatic interactions between IL10 and IL23R-IL12RB2 were detected. Results of imputation analysis highlighted the importance of IL23R regulatory regions in the susceptibility to BD. These findings independently confirm

  16. 12 CFR 563b.330 - How do I price my conversion shares?

    Science.gov (United States)

    2010-01-01

    ... FROM MUTUAL TO STOCK FORM Standard Conversions Offers and Sales of Stock § 563b.330 How do I price my conversion shares? (a) You must sell your conversion shares at a uniform price per share and at a total price... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How do I price my conversion shares? 563b.330...

  17. 12 CFR 563b.435 - What happens to my corporate existence after conversion?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What happens to my corporate existence after... What happens to my corporate existence after conversion? Your corporate existence will continue following your conversion, unless you convert to a state-chartered stock savings association and state law...

  18. Evaluation of interferon-γ and interlukin -12 in sera of pesticides sprayers with or without hepatitis c virus

    International Nuclear Information System (INIS)

    Abdelgawad, M.R.; Wahba, M.; Abdel-Wahab, M.

    2010-01-01

    Both infection with HCV and exposure to pesticides in both developing and developed countries constitutes a major problem indicating severe modulation of the immune system. The present study demonstrated that, the levels of IL-12 and AFP were significantly elevated in pesticide sprayers especially in those who were infected with HCV. Otherwise, the serum level of IFN-γ was decreased in pesticide sprayers especially in those infected with HCV. In addition , liver function tests, blood picture and levels of ammonia and urea were deteriorated in pesticide sprayers especially in those infected with HCV compared with that of the control group. IL-12 and IFN-γ are two important cytokines that play an important role in the immune functions and are considered as indicators of cellular and humoral immune responses and it may be concluded that IFN-γ and IL-12 may play a possible role of pesticides exposure as a risk factor for hepatocellular carcinogenesis especially in the presence of concurrent hepatitis C virus (HCV) infection.

  19. 75 FR 22256 - Difenoconazole Pesticide Tolerances

    Science.gov (United States)

    2010-04-28

    ...; fruit, citrus, group 10; grape; grape, raisin; nut, tree, group 14; onion, bulb, subgroup 3-07A; onion... entities may include, but are not limited to those engaged in the following activities: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide...

  20. 12 CFR 516.55 - What information must I include in my public notice?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What information must I include in my public notice? 516.55 Section 516.55 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Publication Requirements § 516.55 What information must I include in my...

  1. Late-time cosmological approach in mimetic f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Baffou, E.H. [Institut de Mathematiques et de Sciences Physiques (IMSP), Porto-Novo (Benin); Houndjo, M.J.S. [Institut de Mathematiques et de Sciences Physiques (IMSP), Porto-Novo (Benin); Faculte des Sciences et Techniques de Natitingou, Natitingou (Benin); Hamani-Daouda, M. [Universite de Niamey, Departement de Physique, Niamey (Niger); Alvarenga, F.G. [Universidade Federal do Espirito Santo, Departamento de Engenharia e Ciencias Naturais, CEUNES, Sao Mateus, ES (Brazil)

    2017-10-15

    In this paper, we investigate the late-time cosmic acceleration in mimetic f(R, T) gravity with the Lagrange multiplier and potential in a Universe containing, besides radiation and dark energy, a self-interacting (collisional) matter. We obtain through the modified Friedmann equations the main equation that can describe the cosmological evolution. Then, with several models from Q(z) and the well-known particular model f(R, T), we perform an analysis of the late-time evolution. We examine the behavior of the Hubble parameter, the dark energy equation of state and the total effective equation of state and in each case we compare the resulting picture with the non-collisional matter (assumed as dust) and also with the collisional matter in mimetic f(R, T) gravity. The results obtained are in good agreement with the observational data and show that in the presence of the collisional matter the dark energy oscillations in mimetic f(R, T) gravity can be damped. (orig.)

  2. Generation of spherically symmetric metrics in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Amirabi, Z.; Halilsoy, M.; Mazharimousavi, S.H. [Eastern Mediterranean University, Department of Physics, Gazimagusa (Turkey)

    2016-06-15

    In D-dimensional spherically symmetric f(R) gravity there are three unknown functions to be determined from the fourth order differential equations. It is shown that the system remarkably may be integrated to relate two functions through the third one to provide a reduction to second order equations accompanied with a large class of potential solutions. The third function, which acts as the generator of the process, is F(R) = (df(R))/(dR). We recall that our generating function has been employed as a scalar field with an accompanying self-interacting potential previously, which is entirely different from our approach. Reduction of f(R) theory into a system of equations seems to be efficient enough to generate a solution corresponding to each generating function. As particular examples, besides the known ones, we obtain new black hole solutions in any dimension D. We further extend our analysis to cover non-zero energy-momentum tensors. Global monopole and Maxwell sources are given as examples. (orig.)

  3. Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.

    Science.gov (United States)

    Martino, Mikaël M; Maruyama, Kenta; Kuhn, Gisela A; Satoh, Takashi; Takeuchi, Osamu; Müller, Ralph; Akira, Shizuo

    2016-03-22

    Tissue injury and the healing response lead to the release of endogenous danger signals including Toll-like receptor (TLR) and interleukin-1 receptor, type 1 (IL-1R1) ligands, which modulate the immune microenvironment. Because TLRs and IL-1R1 have been shown to influence the repair process of various tissues, we explored their role during bone regeneration, seeking to design regenerative strategies integrating a control of their signalling. Here we show that IL-1R1/MyD88 signalling negatively regulates bone regeneration, in the mouse. Furthermore, IL-1β which is released at the bone injury site, inhibits the regenerative capacities of mesenchymal stem cells (MSCs). Mechanistically, IL-1R1/MyD88 signalling impairs MSC proliferation, migration and differentiation by inhibiting the Akt/GSK-3β/β-catenin pathway. Lastly, as a proof of concept, we engineer a MSC delivery system integrating inhibitors of IL-1R1/MyD88 signalling. Using this strategy, we considerably improve MSC-based bone regeneration in the mouse, demonstrating that this approach may be useful in regenerative medicine applications.

  4. Rational approximations of f(R) cosmography through Pad'e polynomials

    Science.gov (United States)

    Capozziello, Salvatore; D'Agostino, Rocco; Luongo, Orlando

    2018-05-01

    We consider high-redshift f(R) cosmography adopting the technique of polynomial reconstruction. In lieu of considering Taylor treatments, which turn out to be non-predictive as soon as z>1, we take into account the Pad&apose rational approximations which consist in performing expansions converging at high redshift domains. Particularly, our strategy is to reconstruct f(z) functions first, assuming the Ricci scalar to be invertible with respect to the redshift z. Having the so-obtained f(z) functions, we invert them and we easily obtain the corresponding f(R) terms. We minimize error propagation, assuming no errors upon redshift data. The treatment we follow naturally leads to evaluating curvature pressure, density and equation of state, characterizing the universe evolution at redshift much higher than standard cosmographic approaches. We therefore match these outcomes with small redshift constraints got by framing the f(R) cosmology through Taylor series around 0zsimeq . This gives rise to a calibration procedure with small redshift that enables the definitions of polynomial approximations up to zsimeq 10. Last but not least, we show discrepancies with the standard cosmological model which go towards an extension of the ΛCDM paradigm, indicating an effective dark energy term evolving in time. We finally describe the evolution of our effective dark energy term by means of basic techniques of data mining.

  5. F(R Gravity’s Rainbow and Its Einstein Counterpart

    Directory of Open Access Journals (Sweden)

    S. H. Hendi

    2016-01-01

    Full Text Available Motivated by UV completion of general relativity with a modification of a geometry at high energy scale, it is expected to have an energy dependent geometry. In this paper, we introduce charged black hole solutions with power Maxwell invariant source in the context of gravity’s rainbow. In addition, we investigate two classes of F(R gravity’s rainbow solutions. At first, we study energy dependent F(R gravity without energy-momentum tensor, and then we obtain F(R gravity’s rainbow in the presence of conformally invariant Maxwell source. We study geometrical properties of the mentioned solutions and compare their results. We also give some related comments regarding thermodynamical behavior of the obtained solutions and discuss thermal stability of the solutions.

  6. Exploring the liminality: properties of haloes and subhaloes in borderline f(R) gravity

    Science.gov (United States)

    Shi, Difu; Li, Baojiu; Han, Jiaxin; Gao, Liang; Hellwing, Wojciech A.

    2015-09-01

    We investigate the properties of dark matter haloes and subhaloes in an f(R) gravity model with |fR0| = 10-6, using a very-high-resolution N-body simulation. The model is a borderline between being cosmologically interesting and yet still consistent with current data. We find that the halo mass function in this model has a maximum 20 per cent enhancement compared with the Λ-cold-dark-matter (ΛCDM) predictions between z = 1 and 0. Because of the chameleon mechanism which screens the deviation from standard gravity in dense environments, haloes more massive than 1013 h-1 M⊙ in this f(R) model have very similar properties to haloes of similar mass in ΛCDM, while less massive haloes, such as that of the Milky Way, can have steeper inner density profiles and higher velocity dispersions due to their weaker screening. The halo concentration is remarkably enhanced for low-mass haloes in this model due to a deepening of the total gravitational potential. Contrary to the naive expectation, the halo formation time zf is later for low-mass haloes in this model, a consequence of these haloes growing faster than their counterparts in ΛCDM at late times and the definition of zf. Subhaloes, especially those less massive than 1011 h-1 M⊙, are substantially more abundant in this f(R) model for host haloes less massive than 1013 h-1 M⊙. We discuss the implications of these results for the Milky Way satellite abundance problem. Although the overall halo and subhalo properties in this borderline f(R) model are close to their ΛCDM predictions, our results suggest that studies of the Local Group and astrophysical systems, aided by high-resolution simulations, can be valuable for further tests of it.

  7. 41 CFR 301-10.117 - May I keep compensation an airline gives me for voluntarily vacating my seat on my scheduled...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May I keep compensation an airline gives me for voluntarily vacating my seat on my scheduled airline flight when the airline asks for volunteers? 301-10.117 Section 301-10.117 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY)...

  8. The holographic bound in the scalar-tensor and f(R) gravities

    International Nuclear Information System (INIS)

    Firouzjaee, J.T.

    2013-01-01

    The holographic bound has been extended to the different theory of gravities such as scalar-tensor gravity and f(R) gravity according to the Noether charge definition of the entropy for a black hole surface. We have introduced some popular examples of the flat FRW cosmology in order to investigate holographic bound in scalar-tensor and f(R) gravity. Using the holographic bound, we put an additional constraint on scalar-tensor gravity and the f(R) gravity parameters. We also discuss the transformation from Jordan frame to Einstein frame. (orig.)

  9. Le developpement de Limacella glioderma (Fr.) R. Maire

    NARCIS (Netherlands)

    Reijnders, A.F.M.

    1979-01-01

    A comparison of the development of Limacella guttata (Fr.) Konrad & Maublanc with that of L. glioderma (Fr.) R. Maire shows clearly that the latter is of a more primitive type. This conclusion is based on the following observations: a. Limacella guttata has a pileocarpic development: the first

  10. 40 CFR 180.464 - Dimethenamid; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ...) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances...)-acetamide, applied as either the 90:10 or 50:50 S:R isomers, in or on the following food commodities... Pumpkin 0.01 Squash, winter 0.01 (d) Indirect or inadvertent residues. [Reserved] [65 FR 51551, Aug. 24...

  11. 12 CFR 563b.380 - May my employee stock ownership plan purchase conversion shares?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false May my employee stock ownership plan purchase... THE TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Offers and Sales of Stock § 563b.380 May my employee stock ownership plan purchase conversion shares? (a) Your tax-qualified...

  12. Propagating Degrees of Freedom in f(R Gravity

    Directory of Open Access Journals (Sweden)

    Yun Soo Myung

    2016-01-01

    Full Text Available We have computed the number of polarization modes of gravitational waves propagating in the Minkowski background in f(R gravity. These are three of two from transverse-traceless tensor modes and one from a massive trace mode, which confirms the results found in the literature. There is no massless breathing mode and the massive trace mode corresponds to the Ricci scalar. A newly defined metric tensor in f(R gravity satisfies the transverse-traceless (TT condition as well as the TT wave equation.

  13. The coincidence problem in holographic f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Bisabr, Yousef, E-mail: y-bisabr@srttu.edu [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, Tehran 16788 (Iran, Islamic Republic of)

    2011-09-15

    It is well known that f(R) gravity models formulated in the Einstein conformal frame are equivalent to Einstein gravity together with a minimally coupled scalar field. In this case, the scalar field couples with the matter sector and the coupling term is given by the conformal factor. We apply the holographic principle to such interacting models. In a spatially flat universe, we show that the Einstein frame representation of f(R) models leads to a constant ratio of energy densities of dark matter to dark energy.

  14. Distinguishing f(R) theories from general relativity by gravitational lensing effect

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hongguang [Beijing Normal University, Department of Physics, Beijing (China); Aix Marseille Universite et Universite de Toulon, Centre de Physique Theorique (UMR 7332), Marseille (France); Wang, Xin; Li, Haida; Ma, Yongge [Beijing Normal University, Department of Physics, Beijing (China)

    2017-11-15

    The post-Newtonian formulation of a general class of f(R) theories is set up in a third-order approximation. It turns out that the information of a specific form of f(R) gravity is encoded in the Yukawa potential, which is contained in the perturbative expansion of the metric components. Although the Yukawa potential is canceled in the second-order expression of the effective refraction index of light, detailed analysis shows that the difference of the lensing effect between the f(R) gravity and general relativity does appear at the third order when √(f''(0)/f{sup '}(0)) is larger than the distance d{sub 0} to the gravitational source. However, the difference between these two kinds of theories will disappear in the axially symmetric spacetime region. Therefore only in very rare case the f(R) theories are distinguishable from general relativity by gravitational lensing effect in a third-order post-Newtonian approximation. (orig.)

  15. General proof of the entropy principle for self-gravitating fluid in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Xiongjun [Department of Physics and Key Laboratory of Low Dimensional Quantum Structures andQuantum Control of Ministry of Education, Hunan Normal University,Changsha, Hunan 410081 (China); Guo, Minyong [Department of Physics, Beijing Normal University,Beijing 100875 (China); Jing, Jiliang [Department of Physics and Key Laboratory of Low Dimensional Quantum Structures andQuantum Control of Ministry of Education, Hunan Normal University,Changsha, Hunan 410081 (China)

    2016-08-29

    The discussions on the connection between gravity and thermodynamics attract much attention recently. We consider a static self-gravitating perfect fluid system in f(R) gravity, which is an important theory could explain the accelerated expansion of the universe. We first show that the Tolman-Oppenheimer-Volkoff equation of f(R) theories can be obtained by thermodynamical method in spherical symmetric spacetime. Then we prove that the maximum entropy principle is also valid for f(R) gravity in general static spacetimes beyond spherical symmetry. The result shows that if the constraint equation is satisfied and the temperature of fluid obeys Tolmans law, the extrema of total entropy implies other components of gravitational equations. Conversely, if f(R) gravitational equation hold, the total entropy of the fluid should be extremum. Our work suggests a general and solid connection between f(R) gravity and thermodynamics.

  16. Thermodynamic laws for generalized f(R) gravity with curvature-matter coupling

    International Nuclear Information System (INIS)

    Wu Yabo; Zhao Yueyue; Cai Ronggen; Lu Jianbo; Lu Junwang; Gao Xiaojing

    2012-01-01

    The first law and the generalized second law (GSL) of thermodynamics for the generalized f(R) gravity with curvature-matter coupling are studied in the spatially homogeneous, isotropic FRW universe. The research results show that the field equations of the generalized f(R) gravity with curvature-matter coupling can be cast to the form of the first law of thermodynamics with the so-called the entropy production terms dS ¯ and the GSL can be given by considering the FRW universe filled only with ordinary matter enclosed by the dynamical apparent horizon with the Hawking temperature. Furthermore, as a concrete example, by utilizing the GSL the constraints on the gravitational model with f 1 (R)=R+αR l and f 2 (R)=R m are also discussed. It is worth noting these results given by us are quite general and can degenerate to the ones in Einstein's general relativity and pure f(R) gravity with non-coupling and non-minimal coupling as special cases. Comparing with the case of Einstein's general relativity, the appearance of the entropy production term dS ¯ in the first law of thermodynamics demonstrates that the horizon thermodynamics is non-equilibrium one for generalized f(R) gravity with curvature-matter coupling, which is consistent with the arguments given in Akbar and Cai (2007) [13] and Eling et al. (2006) [18].

  17. Occurrence of pesticides in water and sediment collected from amphibian habitats located throughout the United States, 2009-10

    Science.gov (United States)

    Smalling, Kelly L.; Orlando, James L.; Calhoun, Daniel; Battaglin, William A.; Kuivila, Kathryn

    2012-01-01

    Water and bed-sediment samples were collected by the U.S. Geological Survey (USGS) in 2009 and 2010 from 11 sites within California and 18 sites total in Colorado, Georgia, Idaho, Louisiana, Maine, and Oregon, and were analyzed for a suite of pesticides by the USGS. Water samples and bed-sediment samples were collected from perennial or seasonal ponds located in amphibian habitats in conjunction with research conducted by the USGS Amphibian Research and Monitoring Initiative and the USGS Toxic Substances Hydrology Program. Sites selected for this study in three of the states (California, Colorado, and Orgeon) have no direct pesticide application and are considered undeveloped and remote. Sites selected in Georgia, Idaho, Louisiana, and Maine were in close proximity to either agricultural or suburban areas. Water and sediment samples were collected once in 2009 during amphibian breeding seasons. In 2010, water samples were collected twice. The first sampling event coincided with the beginning of the frog breeding season for the species of interest, and the second event occurred 10-12 weeks later when pesticides were being applied to the surrounding areas. Additionally, water was collected during each sampling event to measure dissolved organic carbon, nutrients, and the fungus, Batrachochytrium dendrobatidis, which has been linked to amphibian declines worldwide. Bed-sediment samples were collected once during the beginning of the frog breeding season, when the amphibians are thought to be most at risk to pesticides. Results of this study are reported for the following two geographic scales: (1) for a national scale, by using data from the 29 sites that were sampled from seven states, and (2) for California, by using data from the 11 sampled sites in that state. Water samples were analyzed for 96 pesticides by using gas chromatography/mass spectrometry. A total of 24 pesticides were detected in one or more of the 54 water samples, including 7 fungicides, 10

  18. Constraining f(R gravity in solar system, cosmology and binary pulsar systems

    Directory of Open Access Journals (Sweden)

    Tan Liu

    2018-02-01

    Full Text Available The f(R gravity can be cast into the form of a scalar–tensor theory, and scalar degree of freedom can be suppressed in high-density regions by the chameleon mechanism. In this article, for the general f(R gravity, using a scalar–tensor representation with the chameleon mechanism, we calculate the parametrized post-Newtonian parameters γ and β, the effective gravitational constant Geff, and the effective cosmological constant Λeff. In addition, for the general f(R gravity, we also calculate the rate of orbital period decay of the binary system due to gravitational radiation. Then we apply these results to specific f(R models (Hu–Sawicki model, Tsujikawa model and Starobinsky model and derive the constraints on the model parameters by combining the observations in solar system, cosmological scales and the binary systems.

  19. Alteration of rare-earth-metal cluster iodides R(R6I12Z) through cation substitution

    International Nuclear Information System (INIS)

    Jensen, E.A.; Corbett, J.D.

    2003-01-01

    Four examples of (A x R 1-x )R 6 I 12 Z phases further illustrate the flexibility of the rhombohedral R 7 X 12 Z structure to substitution of heterocations for the isolated R III atoms without destruction of the structure. The examples with R=La, Pr, Z=Fe, Co, Ir, and stoichiometric amounts of A=Na or Ca were prepared by traditional high temperature techniques and characterized by single crystal and Guinier powder X-ray diffraction techniques. Product compositions refined in the parent space group R3-bar from reactions of stoichiometry AR 6 I 12 Z were (Na 0.90 Pr 0.10 )Pr 6 I 12 Ir, (Na 0.954 La 0.046 )La 6 I 12 Fe, and (Ca 0.801 La 0.199 )La 6 I 12 Co. More general characteristics of and trends in the family of R 7 X 12 Z structures are also considered, including distortions of the ideal motif as a function of extremes in the components

  20. A no-hair theorem for black holes in f(R) gravity

    Science.gov (United States)

    Cañate, Pedro

    2018-01-01

    In this work we present a no-hair theorem which discards the existence of four-dimensional asymptotically flat, static and spherically symmetric or stationary axisymmetric, non-trivial black holes in the frame of f(R) gravity under metric formalism. Here we show that our no-hair theorem also can discard asymptotic de Sitter stationary and axisymmetric non-trivial black holes. The novelty is that this no-hair theorem is built without resorting to known mapping between f(R) gravity and scalar–tensor theory. Thus, an advantage will be that our no-hair theorem applies as well to metric f(R) models that cannot be mapped to scalar–tensor theory.

  1. Extension of loop quantum gravity to f(R) theories.

    Science.gov (United States)

    Zhang, Xiangdong; Ma, Yongge

    2011-04-29

    The four-dimensional metric f(R) theories of gravity are cast into connection-dynamical formalism with real su(2) connections as configuration variables. Through this formalism, the classical metric f(R) theories are quantized by extending the loop quantization scheme of general relativity. Our results imply that the nonperturbative quantization procedure of loop quantum gravity is valid not only for general relativity but also for a rather general class of four-dimensional metric theories of gravity.

  2. Signaling through MyD88 regulates leukocyte recruitment after brain injury

    DEFF Research Database (Denmark)

    Babcock, Alicia A; Toft-Hansen, Henrik; Owens, Trevor

    2008-01-01

    hippocampus. We now show that significant leukocyte entry into the EC occurs within 3-12 h of stab injury. Whereas T cells showed small, gradual increases over 8 days, macrophage infiltration was pronounced and peaked within 12-24 h. MyD88 deficiency significantly reduced macrophage and T cell recruitment...... for TNF-alpha, IL-1beta, and CCL2, which increased >50-fold after stab injury in C57BL/6 mice at the time of peak expression, were severely reduced in injured MyD88 knockout mice. Leukocyte recruitment and gene expression were unaffected in TLR2-deficient or TLR4 mutant mice. No significant differences...... in gene expression were observed in mice lacking IL-1R or IL-18R. These data show that MyD88-dependent signaling mediates proinflammatory gene expression and leukocyte recruitment after CNS injury....

  3. 41 CFR 301-10.7 - How should I route my travel?

    Science.gov (United States)

    2010-07-01

    ... travel? 301-10.7 Section 301-10.7 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL EXPENSES 10-TRANSPORTATION EXPENSES General § 301-10.7 How should I route my travel? You must travel to your destination by the usually...

  4. Constraint on reconstructed f(R) gravity models from gravitational waves

    Science.gov (United States)

    Lee, Seokcheon

    2018-06-01

    The gravitational wave (GW) detection of a binary neutron star inspiral made by the Advanced LIGO and Advanced Virgo paves the unprecedented way for multi-messenger observations. The propagation speed of this GW can be scrutinized by comparing the arrival times between GW and neutrinos or photons. It provides the constraint on the mass of the graviton. f(R) gravity theories have the habitual non-zero mass gravitons in addition to usual massless ones. Previously, we show that the model independent f(R) gravity theories can be constructed from the both background evolution and the matter growth with one undetermined parameter. We show that this parameter can be constrained from the graviton mass bound obtained from GW detection. Thus, the GW detection provides the invaluable constraint on the validity of f(R) gravity theories.

  5. 75 FR 6027 - Pesticide Experimental Use Permit; Receipt of Application; Comment Request

    Science.gov (United States)

    2010-02-05

    ... Agrochemicals Ltd. requesting an experimental use permit (EUP) for the end-use product FAL 1800, containing the... Agrochemicals Ltd., (62097-EUP-R). Pesticide Chemical: Prohydrojasmon (PDJ). Summary of Request: Use as a plant...

  6. Cosmic constraint on massive neutrinos in viable f(R) gravity with producing ΛCDM background expansion

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Jianbo; Wu, Yabo; Wang, Yan; Yang, Weiqiang [Liaoning Normal University, Department of Physics, Dalian (China); Liu, Molin [Xinyang Normal University, Department of Physics, Xinyang (China)

    2016-12-15

    Tensions between several cosmic observations were found recently, such as the inconsistent values of H{sub 0} (or σ{sub 8}) were indicated by the different cosmic observations. Introducing the massive neutrinos in ΛCDM could potentially solve the tensions. Viable f(R) gravity producing ΛCDM background expansion with massive neutrinos is investigated in this paper. We fit the current observational data: Planck-2015 CMB, RSD, BAO, and SNIa to constrain the mass of neutrinos in viable f(R) theory. The constraint results at 95% confidence level are: Σm{sub ν} < 0.202 eV for the active-neutrino case, m{sub ν,sterile}{sup eff} < 0.757 eV with N{sub eff} < 3.22 for the sterile neutrino case. For the effects due to the mass of the neutrinos, the constraint results on model parameter at 95% confidence level become f{sub R0} x 10{sup -6} > -1.89 and f{sub R0} x 10{sup -6} > -2.02 for two cases, respectively. It is also shown that the fitting values of several parameters much depend on the neutrino properties, such as the cold dark matter density, the cosmological quantities at matter-radiation equality, the neutrino density and the fraction of baryonic mass in helium. Finally, the constraint result shows that the tension between direct and CMB measurements of H{sub 0} gets slightly weaker in the viable f(R) model than that in the base ΛCDM model. (orig.)

  7. 12 CFR 502.75 - What if I do not pay my fees on time?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What if I do not pay my fees on time? 502.75 Section 502.75 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Fees § 502.75 What if I do not pay my fees on time? (a) Interest. An examination or investigation...

  8. Effect of microalgal treatments on pesticides in water.

    Science.gov (United States)

    Hultberg, Malin; Bodin, Hristina; Ardal, Embla; Asp, Håkan

    2016-01-01

    The effect of the microalgae Chlorella vulgaris on a wide range of different pesticides in water was studied. Treatments included short-term exposure (1 h) to living and dead microalgal biomass and long-term exposure (4 days) to actively growing microalgae. The initial pesticide concentration was 63.5 ± 3.9 µg L(-1). There was no significant overall reduction of pesticides after short-term exposure. A significant reduction of the total amount of pesticides was achieved after the long-term exposure to growing microalgae (final concentration 29.7 ± 1.0 µg L(-1)) compared with the long-term control (37.0 ± 1.2 µg L(-1)). The concentrations of 10 pesticides out of 38 tested were significantly lowered in the long-term algal treatment. A high impact of abiotic factors such as sunlight and aeration for pesticide reduction was observed when the initial control (63.5 ± 3.9 µg L(-1)) and the long-term control (37.0 ± 1.2 µg L(-1)) were compared. The results suggest that water treatment using microalgae, natural inhabitants of polluted surface waters, could be further explored not only for removal of inorganic nutrients but also for removal of organic pollutants in water.

  9. Probing the f(R) formalism through gravitational wave polarizations

    International Nuclear Information System (INIS)

    Alves, M.E.S.; Miranda, O.D.; Araujo, J.C.N. de

    2009-01-01

    The direct observation of gravitational waves (GW) in the near future, and the corresponding determination of the number of independent polarizations, is a powerful tool to test general relativity and alternative theories of gravity. In the present work we use the Newman-Penrose formalism to characterize GWs in quadratic gravity and in a particular class of f(R) Lagrangians. We find that both quadratic gravity and the f(R) theory belong to the most general invariant class of GWs, i.e., they can present up to six independent polarizations of GWs. For a particular combination of the parameters, we find that quadratic gravity can present up to five polarizations states. On the other hand, if we use the Palatini approach for f(R) theories, GWs present only the usual two transverse-traceless polarizations such as in general relativity. Thus, we conclude that the observation of GWs can strongly constrain the suitable formalism for these theories.

  10. On Analytical Solutions of f(R) Modified Gravity Theories in FLRW Cosmologies

    Science.gov (United States)

    Domazet, Silvije; Radovanović, Voja; Simonović, Marko; Štefančić, Hrvoje

    2013-02-01

    A novel analytical method for f(R) modified theories without matter in Friedmann-Lemaitre-Robertson-Walker (FLRW) spacetimes is introduced. The equation of motion for the scale factor in terms of cosmic time is reduced to the equation for the evolution of the Ricci scalar R with the Hubble parameter H. The solution of equation of motion for actions of the form of power law in Ricci scalar R is presented with a detailed elaboration of the action quadratic in R. The reverse use of the introduced method is exemplified in finding functional forms f(R), which leads to specified scale factor functions. The analytical solutions are corroborated by numerical calculations with excellent agreement. Possible further applications to the phases of inflationary expansion and late-time acceleration as well as f(R) theories with radiation are outlined.

  11. f(R in Holographic and Agegraphic Dark Energy Models and the Generalized Uncertainty Principle

    Directory of Open Access Journals (Sweden)

    Barun Majumder

    2013-01-01

    Full Text Available We studied a unified approach with the holographic, new agegraphic, and f(R dark energy model to construct the form of f(R which in general is responsible for the curvature driven explanation of the very early inflation along with presently observed late time acceleration. We considered the generalized uncertainty principle in our approach which incorporated the corrections in the entropy-area relation and thereby modified the energy densities for the cosmological dark energy models considered. We found that holographic and new agegraphic f(R gravity models can behave like phantom or quintessence models in the spatially flat FRW universe. We also found a distinct term in the form of f(R which goes as R 3 / 2 due to the consideration of the GUP modified energy densities. Although the presence of this term in the action can be important in explaining the early inflationary scenario, Capozziello et al. recently showed that f(R ~ R 3 / 2 leads to an accelerated expansion, that is, a negative value for the deceleration parameter q which fits well with SNeIa and WMAP data.

  12. Application of ACD/LABS 12 program for determination of conditions for experimental membrane extraction of pesticides

    Directory of Open Access Journals (Sweden)

    Đorđević J.

    2010-01-01

    Full Text Available This paper analyzes the conditions for membrane extraction of pesticides using ACD / LABS 12 program. The program contains a large database of more than 2000 compounds and their ionized species, for determining the pKa, further analysis includes 600 new compounds confirmed by Hammett’s equation, which gives more precise values for logD and solubility. The 16 pesticides of different classes (organophosphates, carbamates, carbamidas, neonicotinoids etc. and polarities commonly used in Serbia were examined. The program is used to calculate logD, pKa and solubility at different pH values for the mixture of pesticides. Based on the calculated values, the conditions for the extraction of pesticides in water using two-phase liquid-liquid membrane extraction were optimized.

  13. 78 FR 3422 - Notice of Receipt of Pesticide Products; Registration Applications

    Science.gov (United States)

    2013-01-16

    ... included in any currently registered pesticide products. Pursuant to the Federal Insecticide, Fungicide.... Box 667, Ames, IA 50010. Active Ingredient: Trichoderma fertile strain JM41R at 96.0%. Product Type: Fungicide. Proposed Use: Manufacturing use. Contact: Jeannine Kausch, (703) 347-8920, email address: kausch...

  14. Reconstructing an f(R) model from holographic dark energy: using the observational evidence

    International Nuclear Information System (INIS)

    Saaidi, Kh; Aghamohammadi, A

    2012-01-01

    We investigate the correspondence relation between f(R) gravity and an interacting holographic dark energy (HDE). By obtaining the conditions needed for some observational evidence such as positive acceleration expansion of the Universe, crossing the phantom divide line and validity of the thermodynamics second law in an interacting HDE model and corresponding it with the f(R) model of gravity, we find a viable f(R) model that can explain the present Universe. We also obtain the explicit evolutionary forms of the corresponding scalar field, potential and scale factor of the Universe. (paper)

  15. String duality transformations in f(R) gravity from Noether symmetry approach

    Energy Technology Data Exchange (ETDEWEB)

    Capozziello, Salvatore [Dipartimento di Fisica, Università di Napoli ' ' Federico II' ' , Compl. Univ. di Monte S. Angelo, Edificio G, Via Cinthia, I-80126, Napoli (Italy); Gionti, Gabriele S.J. [Specola Vaticana, Vatican City, V-00120, Vatican City State (Vatican City State, Holy See); Vernieri, Daniele, E-mail: capozziello@na.inf.it, E-mail: ggionti@as.arizona.edu, E-mail: vernieri@iap.fr [Sorbonne Universités, UPMC Univ Paris 6 et CNRS, UMR 7095, Institut d' Astrophysique de Paris, GReCO, 98bis Bd Arago, 75014 Paris (France)

    2016-01-01

    We select f(R) gravity models that undergo scale factor duality transformations. As a starting point, we consider the tree-level effective gravitational action of bosonic String Theory coupled with the dilaton field. This theory inherits the Busher's duality of its parent String Theory. Using conformal transformations of the metric tensor, it is possible to map the tree-level dilaton-graviton string effective action into f(R) gravity, relating the dilaton field to the Ricci scalar curvature. Furthermore, the duality can be framed under the standard of Noether symmetries and exact cosmological solutions are derived. Using suitable changes of variables, the string-based f(R) Lagrangians are shown in cases where the duality transformation becomes a parity inversion.

  16. String duality transformations in f(R) gravity from Noether symmetry approach

    International Nuclear Information System (INIS)

    Capozziello, Salvatore; Gionti, Gabriele S.J.; Vernieri, Daniele

    2016-01-01

    We select f(R) gravity models that undergo scale factor duality transformations. As a starting point, we consider the tree-level effective gravitational action of bosonic String Theory coupled with the dilaton field. This theory inherits the Busher's duality of its parent String Theory. Using conformal transformations of the metric tensor, it is possible to map the tree-level dilaton-graviton string effective action into f(R) gravity, relating the dilaton field to the Ricci scalar curvature. Furthermore, the duality can be framed under the standard of Noether symmetries and exact cosmological solutions are derived. Using suitable changes of variables, the string-based f(R) Lagrangians are shown in cases where the duality transformation becomes a parity inversion

  17. Unifying inflation with dark energy in modified F(R) Horava-Lifshitz gravity

    International Nuclear Information System (INIS)

    Elizalde, E.; Saez-Gomez, D.; Nojiri, S.; Odintsov, S.D.

    2010-01-01

    We study FRW cosmology for a non-linear modified F(R) Horava-Lifshitz gravity which has a viable convenient counterpart. A unified description of early-time inflation and late-time acceleration is possible in this theory, but the cosmological dynamic details are generically different from the ones of the convenient viable F(R) model. Remarkably, for some specific choice of parameters they do coincide. The emergence of finite-time future singularities is investigated in detail. It is shown that these singularities can be cured by adding an extra, higher-derivative term, which turns out to be qualitatively different when compared with the corresponding one of the convenient F(R) theory. (orig.)

  18. 76 FR 41246 - Pesticide Program Dialogue Committee, Pesticide Registration Improvement Act Process Improvement...

    Science.gov (United States)

    2011-07-13

    ... Committee, Pesticide Registration Improvement Act Process Improvement Workgroup; Notice of Public Meeting...) Process Improvement Work Group. EPA plans to meet its ESA consultation obligations through the pesticide... a pesticide during the registration review process. This meeting of the PRIA Process Improvement...

  19. Late time acceleration of the universe in f(R) gravity model

    International Nuclear Information System (INIS)

    Mukherjee, Ankan

    2014-01-01

    In this work, a new way to look at the nature of late time dynamics of the universe for f(R) gravity models using the contracted Bianchi Identity has been proposed. As the Einstein field equations contain derivatives of the curvature scalar R, the contracted Bianchi identity yields a second order nonlinear differential equation in H, the Hubble parameter. This equation is studied for two particular forms of f(R), and the late time behaviour of the model is discussed. (author)

  20. Stability of the Einstein static universe in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shabani, Hamid [University of Sistan and Baluchestan, Physics Department, Faculty of Sciences, Zahedan (Iran, Islamic Republic of); Ziaie, Amir Hadi [Kahnooj Branch, Islamic Azad University, Department of Physics, Kerman (Iran, Islamic Republic of)

    2017-01-15

    The Einstein static (ES) universe has played a major role in various emergent scenarios recently proposed in order to cure the problem of the initial singularity of the standard model of cosmology. In the model we address, we study the existence and stability of an ES universe in the context of f(R, T) modified theories of gravity. Considering specific forms of the f(R, T) function, we seek for the existence of solutions representing ES state. Using dynamical system techniques along with numerical analysis, we find two classes of solutions: the first one is always unstable of the saddle type, while the second is always stable so that its dynamical behavior corresponds to a center equilibrium point. The importance of the second class of solutions is due to the significant role they play in constructing non-singular emergent models in which the universe could have experienced past-eternally a series of infinite oscillations about such an initial static state after which it enters, through a suitable physical mechanism, to an inflationary era. Considering specific forms for the functionality of f(R, T), we show that this theory is capable of providing cosmological solutions which admit emergent universe (EU) scenarios. We also investigate homogeneous scalar perturbations for the mentioned models. The stability regions of the solutions are parametrized by a linear equation of state (EoS) parameter and other free parameters that will be introduced for the models. Our results suggest that modifications in f(R, T) gravity would lead to stable solutions which are unstable in f(R) gravity model. (orig.)

  1. Stability of the Einstein static universe in f(R, T) gravity

    International Nuclear Information System (INIS)

    Shabani, Hamid; Ziaie, Amir Hadi

    2017-01-01

    The Einstein static (ES) universe has played a major role in various emergent scenarios recently proposed in order to cure the problem of the initial singularity of the standard model of cosmology. In the model we address, we study the existence and stability of an ES universe in the context of f(R, T) modified theories of gravity. Considering specific forms of the f(R, T) function, we seek for the existence of solutions representing ES state. Using dynamical system techniques along with numerical analysis, we find two classes of solutions: the first one is always unstable of the saddle type, while the second is always stable so that its dynamical behavior corresponds to a center equilibrium point. The importance of the second class of solutions is due to the significant role they play in constructing non-singular emergent models in which the universe could have experienced past-eternally a series of infinite oscillations about such an initial static state after which it enters, through a suitable physical mechanism, to an inflationary era. Considering specific forms for the functionality of f(R, T), we show that this theory is capable of providing cosmological solutions which admit emergent universe (EU) scenarios. We also investigate homogeneous scalar perturbations for the mentioned models. The stability regions of the solutions are parametrized by a linear equation of state (EoS) parameter and other free parameters that will be introduced for the models. Our results suggest that modifications in f(R, T) gravity would lead to stable solutions which are unstable in f(R) gravity model. (orig.)

  2. 77 FR 38285 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2012-06-27

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2012-0101; FRL-9348-5] Pesticide Products... announces receipt of applications to register pesticide products containing new active ingredients not... Pollution Prevention Division (7511P) or the Registration Division (7505P), Office of Pesticide Programs...

  3. 77 FR 4248 - Cyazofamid; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2012-01-27

    ... basil, fresh and dried. This action is in response to EPA's granting of an emergency exemption under... pesticide on basil. This regulation establishes a maximum permissible level for residues of cyazofamid in or... of the fungicide cyazofamid, in or on fresh basil at 12 parts per million (ppm), and on dried basil...

  4. An Innovative Rapid Method for Analysis of 10 Organophosphorus Pesticide Residues in Wheat by HS-SPME-GC-FPD/MSD.

    Science.gov (United States)

    Du, Xin; Ren, YongLin; Beckett, Stephen J

    2016-01-01

    The rapid detection of pesticide residues in wheat has become a top food security priority. A solvent-free headspace solid-phase microextraction (HS-SPME) has been evaluated for rapid screening of organophosphorus pesticide (OPP) residues in wheat with high sensitivity. Individual wheat samples (1.7 g), spiked with 10 OPPs, were placed in a 4 mL sealed amber glass vial and heated at 60°C for 45 min. During this time, the OPP residues were extracted with a 50 μm/30 μm divinylbenzene (DVB)/carboxen (CAR)/plasma desorption mass spectroscopy polydimethylsiloxane (PDMS) fiber from the headspace above the sample. The fiber was then removed and injected into the GC injection port at 250°C for desorption of the extracted chemicals. The multiple residues were identified by a GC mass spectrometer detector (GC-MSD) and quantified with a GC flame photometric detector (GC-FPD). Seven spiked levels of 10 OPPs on wheat were analyzed. The GC responses for a 50 μm/30 μm DVB/CAR/PDMS fiber increased with increasing spiking levels, yielding significant (R(2) > 0.98) linear regressions. The lowest LODs of the multiple pesticide standards were evaluated under the conditions of the validation study in a range of levels from 0 (control) to 100 ng of pesticide residue per g of wheat that separated on a low-polar GC capillary column (Agilent DB-35UI). The results of the HS-SPME method were compared with the QuEChERS AOAC 2007.01 method and they showed several advantages over the latter. These included improved sensitivity, selectivity, and simplicity.

  5. Somatic mutations in leafs of tobacco seedlings induced by ionizing radiation and pesticide

    International Nuclear Information System (INIS)

    Shin, H. S.; Kim, J. K.; Song, H. S.; Lee, Y. I.

    2001-01-01

    Somatic mutations induced by the combined treatment of pesticide and ionizing radiation were analyzed in the leaves of tobacco seedlings. The pesticide (1,5 and 10 ppm of parathion) was sprayed directly onto the seedlings. The seedlings, with or without pretreatment of pesticide, were irradiated with 0.1 ∼10 Gy of gamma ray. The difference in the somatic mutation frequencies were not significant among groups treated with different concentration of pesticide. The somatic mutations in tobacco seedlings irradiated with gamma-ray showed a clear dose-response relationship in a range of 0.1 to 10 Gy. However, the combined treatment of pesticide and radiation did not cause any synergistic enhancement in the mutation frequencies. The highest efficiency in the induction of somatic mutations could be obtained by irradiating the seedlings with 5 Gy, 12 hours after 1 ppm of pesticide treatment, or 24 hours after 5 ppm of pesticide treatment

  6. Exact solutions for scalar field cosmology in f(R) gravity

    Science.gov (United States)

    Maharaj, S. D.; Goswami, R.; Chervon, S. V.; Nikolaev, A. V.

    2017-09-01

    We study scalar field FLRW cosmology in the content of f(R) gravity. Our consideration is restricted to the spatially flat Friedmann universe. We derived the general evolution equations of the model, and showed that the scalar field equation is automatically satisfied for any form of the f(R) function. We also derived representations for kinetic and potential energies, as well as for the acceleration in terms of the Hubble parameter and the form of the f(R) function. Next we found the exact cosmological solutions in modified gravity without specifying the f(R) function. With negligible acceleration of the scalar curvature, we found that the de Sitter inflationary solution is always attained. Also we obtained new solutions with special restrictions on the integration constants. These solutions contain oscillating, accelerating, decelerating and even contracting universes. For further investigation, we selected special cases which can be applied with early or late inflation. We also found exact solutions for the general case for the model with negligible acceleration of the scalar curvature in terms of special Airy functions. Using initial conditions which represent the universe at the present epoch, we determined the constants of integration. This allows for the comparison of the scale factor in the new solutions with that for current stage of the universe evolution in the ΛCDM model.

  7. Chameleon halo modeling in f(R) gravity

    International Nuclear Information System (INIS)

    Li Yin; Hu, Wayne

    2011-01-01

    We model the chameleon effect on cosmological statistics for the modified gravity f(R) model of cosmic acceleration. The chameleon effect, required to make the model compatible with local tests of gravity, reduces force enhancement as a function of the depth of the gravitational potential wells of collapsed structure and so is readily incorporated into a halo model by including parameters for the chameleon mass threshold and rapidity of transition. We show that the abundance of halos around the chameleon mass threshold is enhanced by both the merging from below and the lack of merging to larger masses. This property also controls the power spectrum in the nonlinear regime and we provide a description of the transition to the linear regime that is valid for a wide range of f(R) models.

  8. 20 Years of Air-Water Gas Exchange Observations for Pesticides in the Western Arctic Ocean.

    Science.gov (United States)

    Jantunen, Liisa M; Wong, Fiona; Gawor, Anya; Kylin, Henrik; Helm, Paul A; Stern, Gary A; Strachan, William M J; Burniston, Deborah A; Bidleman, Terry F

    2015-12-01

    The Arctic has been contaminated by legacy organochlorine pesticides (OCPs) and currently used pesticides (CUPs) through atmospheric transport and oceanic currents. Here we report the time trends and air-water exchange of OCPs and CUPs from research expeditions conducted between 1993 and 2013. Compounds determined in both air and water were trans- and cis-chlordanes (TC, CC), trans- and cis-nonachlors (TN, CN), heptachlor exo-epoxide (HEPX), dieldrin (DIEL), chlorobornanes (ΣCHBs and toxaphene), dacthal (DAC), endosulfans and metabolite endosulfan sulfate (ENDO-I, ENDO-II, and ENDO SUL), chlorothalonil (CHT), chlorpyrifos (CPF), and trifluralin (TFN). Pentachloronitrobenzene (PCNB and quintozene) and its soil metabolite pentachlorothianisole (PCTA) were also found in air. Concentrations of most OCPs declined in surface water, whereas some CUPs increased (ENDO-I, CHT, and TFN) or showed no significant change (CPF and DAC), and most compounds declined in air. Chlordane compound fractions TC/(TC + CC) and TC/(TC + CC + TN) decreased in water and air, while CC/(TC + CC + TN) increased. TN/(TC + CC + TN) also increased in air and slightly, but not significantly, in water. These changes suggest selective removal of more labile TC and/or a shift in chlordane sources. Water-air fugacity ratios indicated net volatilization (FR > 1.0) or near equilibrium (FR not significantly different from 1.0) for most OCPs but net deposition (FR exchange direction of other CUPs varied. Understanding the processes and current state of air-surface exchange helps to interpret environmental exposure and evaluate the effectiveness of international protocols and provides insights for the environmental fate of new and emerging chemicals.

  9. Thick brane in f(R) gravity with Palatini dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D.; Losano, L. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Menezes, R. [Universidade Federal da Paraiba, Departamento de Ciencias Exatas, Rio Tinto, PB (Brazil); Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil); Olmo, Gonzalo J. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidad de Valencia, Departamento de Fisica Teorica, IFIC, Centro Mixto Universidad de Valencia-CSIC, Burjassot, Valencia (Spain); Rubiera-Garcia, D. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidade de Lisboa, Faculdade de Ciencias, Instituto de Astrofisica e Ciencias do Espaco, Lisbon (Portugal); Fudan University, Department of Physics, Center for Field Theory and Particle Physics, Shanghai (China)

    2015-12-15

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R) = R + εR{sup n}, where the small parameter ε controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections. (orig.)

  10. 75 FR 33705 - Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Change to...

    Science.gov (United States)

    2010-06-15

    ... Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Change to Labeling... the pesticide container and containment regulations to provide a 4-month extension of the 40 CFR 156... pesticide labels to comply with the label requirements in the container and containment regulations. DATES...

  11. Physical attributes of anisotropic compact stars in f(R, G) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M.F.; Zia, Saeeda [National University of Computer and Emerging Sciences, Department of Sciences and Humanities, Lahore (Pakistan)

    2017-07-15

    Modified gravity is one of the potential candidates to explain the accelerated expansion of the universe. Current study highlights the materialization of anisotropic compact stars in the context of f(R, G) theory of gravity. In particular, to gain insight in the physical behavior of three stars namely, Her X1, SAX J 1808-3658 and 4U 1820-30, energy density, and radial and tangential pressures are calculated. The f(R, G) gravity model is split into a Starobinsky like f(R) model and a power law f(G) model. The main feature of the work is a 3-dimensional graphical analysis in which, anisotropic measurements, energy conditions and stability attributes of these stars are discussed. It is shown that all three stars behave as usual for positive values of the f(G) model parameter n. (orig.)

  12. 12 CFR 563b.110 - Who must review my business plan?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Who must review my business plan? 563b.110... business plan? (a) Your chief executive officer and members of the board of directors must review, and at least two-thirds of your board of directors must approve, the business plan. (b) Your chief executive...

  13. Rapid screening and quantification of residual pesticides and illegal adulterants in red wine by direct analysis in real time mass spectrometry.

    Science.gov (United States)

    Guo, Tianyang; Fang, Pingping; Jiang, Juanjuan; Zhang, Feng; Yong, Wei; Liu, Jiahui; Dong, Yiyang

    2016-11-04

    A rapid method to screen and quantify multi-class analytic targets in red wine has been developed by direct analysis in real time (DART) coupled with triple quadruple tandem mass spectrometry (QqQ-MS). A modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) procedure was used for increasing analytical speed and reducing matrix effect, and the multiple reaction monitoring (MRM) in DART-MS/MS ensured accurate analysis. One bottle of wine containing 50 pesticides and 12 adulterants, i.e., preservatives, antioxidant, sweeteners, and azo dyes, could be totally determined less than 12min. This method exhibited proper linearity (R 2 ≥0.99) in the range of 1-1000ng/mL for pesticides and 10-5000ng/mL for adulterants. The limits of detection (LODs) were obtained in a 0.5-50ng/mL range for pesticides and 5-50ng/mL range for adulterants, and the limits of quantification (LOQs) were in a 1-100ng/mL range for pesticides and 10-250ng/mL range for adulterants. Three spiked levels for each analyte in wine were evaluated, and the recoveries were in a scope of 75-120%. The results demonstrated DART-MS/MS was a rapid and simple method, and could be applied to rapid analyze residual pesticides and illegal adulterants in a large quantities of red wine. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. 41 CFR 301-10.308 - What will I be reimbursed if I park my POV at a common carrier terminal while I am away from my...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What will I be reimbursed if I park my POV at a common carrier terminal while I am away from my official station? 301-10.308... am away from my official station? Your agency may reimburse your parking fee as an allowable...

  15. rändrat omhändertagande av patienter med uretärsten : - Lärdomar från ett förbättringsarbete

    OpenAIRE

    Khatami, Annelie

    2014-01-01

    Bakgrund: Omkring 10-15 % av befolkningen, oftast i arbetsför ålder, riskerar att någon gång drabbas av njursten. Nationella riktlinjer för njurstensbehandling saknas, men studier stödjer behandling inom 48 timmar för snabb symtomlindring och minskade besvärr patienten. Inom studerad verksamhet var tiden från diagnos till behandling lång och återinläggningarna var många, varför ett förbättringsarbete initierades. Syfte: Syftet med förbättringsarbetet var att halvera tiden från diagnos till...

  16. Generalisation for regular black holes on general relativity to f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Manuel E. [Universidade Federal do Para Campus Universitario de Abaetetuba, Faculdade de Ciencias Exatas e Tecnologia, Abaetetuba, Para (Brazil); Universidade Federal do Para, Faculdade de Fisica, PPGF, Belem, Para (Brazil); Fabris, Julio C. [Universidade Federal do Espirito Santo, Vitoria, ES (Brazil); National Research Nuclear University MEPhI, Moscow (Russian Federation); Junior, Ednaldo L.B. [Universidade Federal do Para, Faculdade de Fisica, PPGF, Belem, Para (Brazil); Universidade Federal do Para, Campus Universitario de Tucurui, Faculdade de Engenharia da Computacao, Tucurui, Para (Brazil); Marques, Glauber T. [Universidade Federal Rural da Amazonia ICIBE - LASIC, Belem, PA (Brazil)

    2016-05-15

    IIn this paper, we determine regular black hole solutions using a very general f(R) theory, coupled to a nonlinear electromagnetic field given by a Lagrangian L{sub NED}. The functions f(R) and L{sub NED} are in principle left unspecified. Instead, the model is constructed through a choice of the mass function M(r) presented in the metric coefficients. Solutions which have a regular behaviour of the geometric invariants are found. These solutions have two horizons, the event horizon and the Cauchy horizon. All energy conditions are satisfied in the whole space-time, except the strong energy condition (SEC), which is violated near the Cauchy horizon.We present also a new theorem related to the energy conditions in f(R) gravity, re-obtaining the well-known conditions in the context of general relativity when the geometry of the solution is the same. (orig.)

  17. Static spherically symmetric wormholes in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Zubair, M.; Ahmad, Yasir [Institute Of Information Technology, Department of Mathematics, COMSATS, Lahore (Pakistan); Waheed, Saira [Prince Mohammad Bin Fahd University, Al Khobar (Saudi Arabia)

    2016-08-15

    In this work, we explore wormhole solutions in f(R, T) theory of gravity, where R is the scalar curvature and T is the trace of stress-energy tensor of matter. To investigate this, we consider a static spherically symmetric geometry with matter contents as anisotropic, isotropic, and barotropic fluids in three separate cases. By taking into account the Starobinsky f(R) model, we analyze the behavior of energy conditions for these different kinds of fluids. It is shown that the wormhole solutions can be constructed without exotic matter in few regions of space-time. We also give the graphical illustration of the results obtained and discuss the equilibrium picture for the anisotropic case only. It is concluded that the wormhole solutions with anisotropic matter are realistic and stable in this theory of gravity. (orig.)

  18. 36 CFR 1254.12 - Will NARA log or inspect my computer, other equipment, and notes?

    Science.gov (United States)

    2010-07-01

    ... personal notes into the research room. In research rooms that permit taking in your notes, a NARA or... computer, other equipment, and notes? 1254.12 Section 1254.12 Parks, Forests, and Public Property NATIONAL... MATERIALS General Information § 1254.12 Will NARA log or inspect my computer, other equipment, and notes? (a...

  19. 41 CFR 302-12.4 - For what relocation services expenses will my agency pay?

    Science.gov (United States)

    2010-07-01

    ... actual expenses the company incurs on your behalf, payment to the company is limited to what you would... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false For what relocation services expenses will my agency pay? 302-12.4 Section 302-12.4 Public Contracts and Property Management...

  20. Electrochemical Impedance Study of Reduction Kinetics of the Pesticide Vinclozoline

    Czech Academy of Sciences Publication Activity Database

    Pospíšil, Lubomír; Sokolová, Romana; Colombini, M. P.; Giannarelli, S.; Fuoco, R.

    2000-01-01

    Roč. 67, - (2000), s. 305-312 ISSN 0026-265X R&D Projects: GA MŠk OC D15.10; GA ČR GA203/97/1048 Institutional research plan: CEZ:AV0Z4040901 Keywords : electrochemical impedance * pesticide s * vinclozoline Subject RIV: CG - Electrochemistry Impact factor: 0.884, year: 2000

  1. Power-law cosmic expansion in f(R) gravity models

    International Nuclear Information System (INIS)

    Goheer, Naureen; Larena, Julien; Dunsby, Peter K. S.

    2009-01-01

    We show that within the class of f(R) gravity theories, Friedmann-Lemaitre-Robertson-Walker power-law perfect fluid solutions only exist for R n gravity. This significantly restricts the set of exact cosmological solutions which have similar properties to what is found in standard general relativity.

  2. Niveaux de résidus de pesticides organochlorés dans les produits ...

    African Journals Online (AJOL)

    L'objectif de cette étude est de déterminer le contenu en résidus de quelques pesticides organochlorés du cacao masse, des tourteaux et du beurre de cacao. Pour se faire, 75 échantillons de fèves de cacao ont été prélevés auprès des planteurs et coopératives du département d'Agboville et des exportateurs des ports de ...

  3. Pesticide Applicator Profiling: Using Polycom[R] Distance Delivery for Continuing Education and Characterizing Florida's Licensed Applicators

    Science.gov (United States)

    Fishel, Fred; Langeland, Ken

    2011-01-01

    The University of Florida offers continuing education units (CEUs) via distance technology using Polycom[R] to meet requirements for applicators of pesticides to renew their licenses. A large statewide event conducted in 2010 also included a needs assessment of this group concerning CEUs. Results indicate that these applicators strongly prefer…

  4. The simplest non-minimal matter-geometry coupling in the f(R, T) cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Moraes, P.H.R.S. [ITA - Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Paulo (Brazil); Sahoo, P.K. [Birla Institute of Technology and Science-Pilani, Department of Mathematics, Hyderabad (India)

    2017-07-15

    f(R, T) gravity is an extended theory of gravity in which the gravitational action contains general terms of both the Ricci scalar R and the trace of the energy-momentum tensor T. In this way, f(R, T) models are capable of describing a non-minimal coupling between geometry (through terms in R) and matter (through terms in T). In this article we construct a cosmological model from the simplest non-minimal matter-geometry coupling within the f(R, T) gravity formalism, by means of an effective energy-momentum tensor, given by the sum of the usual matter energy-momentum tensor with a dark energy contribution, with the latter coming from the matter-geometry coupling terms. We apply the energy conditions to our solutions in order to obtain a range of values for the free parameters of the model which yield a healthy and well-behaved scenario. For some values of the free parameters which are submissive to the energy conditions application, it is possible to predict a transition from a decelerated period of the expansion of the universe to a period of acceleration (dark energy era). We also propose further applications of this particular case of the f(R, T) formalism in order to check its reliability in other fields, rather than cosmology. (orig.)

  5. The simplest non-minimal matter-geometry coupling in the f(R, T) cosmology

    International Nuclear Information System (INIS)

    Moraes, P.H.R.S.; Sahoo, P.K.

    2017-01-01

    f(R, T) gravity is an extended theory of gravity in which the gravitational action contains general terms of both the Ricci scalar R and the trace of the energy-momentum tensor T. In this way, f(R, T) models are capable of describing a non-minimal coupling between geometry (through terms in R) and matter (through terms in T). In this article we construct a cosmological model from the simplest non-minimal matter-geometry coupling within the f(R, T) gravity formalism, by means of an effective energy-momentum tensor, given by the sum of the usual matter energy-momentum tensor with a dark energy contribution, with the latter coming from the matter-geometry coupling terms. We apply the energy conditions to our solutions in order to obtain a range of values for the free parameters of the model which yield a healthy and well-behaved scenario. For some values of the free parameters which are submissive to the energy conditions application, it is possible to predict a transition from a decelerated period of the expansion of the universe to a period of acceleration (dark energy era). We also propose further applications of this particular case of the f(R, T) formalism in order to check its reliability in other fields, rather than cosmology. (orig.)

  6. Compact stars in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Das, Amit; Guha, B.K. [Indian Institute of Engineering Science and Technology, Department of Physics, Howrah, West Bengal (India); Rahaman, Farook [Jadavpur University, Department of Mathematics, Kolkata, West Bengal (India); Ray, Saibal [Government College of Engineering and Ceramic Technology, Department of Physics, Kolkata, West Bengal (India)

    2016-12-15

    In the present paper we generate a set of solutions describing the interior of a compact star under f(R, T) theory of gravity which admits conformal motion. An extension of general relativity, the f(R, T) gravity is associated to Ricci scalar R and the trace of the energy-momentum tensor T. To handle the Einstein field equations in the form of differential equations of second order, first of all we adopt the Lie algebra with conformal Killing vectors (CKV) which enable one to get a solvable form of such equations and second we consider the equation of state (EOS) p = ωρ with 0 < ω < 1 for the fluid distribution consisting of normal matter, ω being the EOS parameter. We therefore analytically explore several physical aspects of the model to represent behavior of the compact stars such as - energy conditions, TOV equation, stability of the system, Buchdahl condition, compactness and redshift. It is checked that the physical validity and the acceptability of the present model within the specified observational constraint in connection to a dozen of the compact star candidates are quite satisfactory. (orig.)

  7. 12 CFR 563b.115 - How will OTS review my business plan?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How will OTS review my business plan? 563b.115... business plan? (a) OTS will review your business plan to determine that it demonstrates a safe and sound... will be determinative. OTS will review every case on its merits. (b) You must file your business plan...

  8. Brane f(R) gravity and the dark side of the universe

    International Nuclear Information System (INIS)

    Borzou, A.; Sepangi, H. R.; Shahidi, S.; Yousefi, R.

    2009-01-01

    We consider a brane world scenario in which the bulk action is assumed to have the form of a generic function of the Ricci scalar f(R) and derive the resulting Einstein field equation on the brane. In a constant curvature bulk a conserved geometric quantity appears in the field equations which can be associated with matter. We present spherically symmetric solutions which account for galaxy rotation curves in a specific form. Then cosmological solutions by assuming a specific form for f(R) are derived which can explain an accelerated expanding universe.

  9. Degradation of the Neonicotinoid Pesticides in the Atmospheric Pressure Ionization Source

    Science.gov (United States)

    Chai, Yunfeng; Chen, Hongping; Liu, Xin; Lu, Chengyin

    2018-02-01

    During the analysis of neonicotinoid pesticide standards (thiamethoxam, clothianidin, imidacloprid, acetamiprid, and thiacloprid) by mass spectrometry, the degradation of these pesticides (M-C=N-R is degraded into M-C=O, M is the skeleton moiety, and R is NO2 or CN) was observed in the atmospheric pressure ionization interfaces (ESI and APCI). In APCI, the degradation of all the five neonicotinoid pesticides studied took place, and the primary mechanism was in-source ion/molecule reaction, in which a molecule of water (confirmed by use of H2 18O) attacked the carbon of the imine group accompanying with loss of NH2R (R=NO2, CN). For the nitroguanidine neonicotinoid pesticides (R=NO2, including thiamethoxam, clothianidin, and imidacloprid), higher auxiliary gas heater temperature also contributed to their degradation in APCI due to in-source pyrolysis. The degradation of the five neonicotinoid pesticides studied in ESI was not significant. In ESI, only the nitroguanidine neonicotinoid pesticides could generate the degradation products through in-source fragmentation mechanism. The degradation of cyanoamidine neonicotinoid pesticides (R=CN, including acetamiprid and thiacloprid) in ESI was not observed. The degradation of neonicotinoid pesticides in the ion source of mass spectrometer renders some adverse consequences, such as difficulty interpreting the full-scan mass spectrum, reducing the sensitivity and accuracy of quantitative analysis, and misleading whether these pesticides have degraded in the real samples. Therefore, a clear understanding of these unusual degradation reactions should facilitate the analysis of neonicotinoid pesticides by atmospheric pressure ionization mass spectrometry.

  10. Degradation of the Neonicotinoid Pesticides in the Atmospheric Pressure Ionization Source.

    Science.gov (United States)

    Chai, Yunfeng; Chen, Hongping; Liu, Xin; Lu, Chengyin

    2018-02-01

    During the analysis of neonicotinoid pesticide standards (thiamethoxam, clothianidin, imidacloprid, acetamiprid, and thiacloprid) by mass spectrometry, the degradation of these pesticides (M-C=N-R is degraded into M-C=O, M is the skeleton moiety, and R is NO 2 or CN) was observed in the atmospheric pressure ionization interfaces (ESI and APCI). In APCI, the degradation of all the five neonicotinoid pesticides studied took place, and the primary mechanism was in-source ion/molecule reaction, in which a molecule of water (confirmed by use of H 2 18 O) attacked the carbon of the imine group accompanying with loss of NH 2 R (R=NO 2 , CN). For the nitroguanidine neonicotinoid pesticides (R=NO 2 , including thiamethoxam, clothianidin, and imidacloprid), higher auxiliary gas heater temperature also contributed to their degradation in APCI due to in-source pyrolysis. The degradation of the five neonicotinoid pesticides studied in ESI was not significant. In ESI, only the nitroguanidine neonicotinoid pesticides could generate the degradation products through in-source fragmentation mechanism. The degradation of cyanoamidine neonicotinoid pesticides (R=CN, including acetamiprid and thiacloprid) in ESI was not observed. The degradation of neonicotinoid pesticides in the ion source of mass spectrometer renders some adverse consequences, such as difficulty interpreting the full-scan mass spectrum, reducing the sensitivity and accuracy of quantitative analysis, and misleading whether these pesticides have degraded in the real samples. Therefore, a clear understanding of these unusual degradation reactions should facilitate the analysis of neonicotinoid pesticides by atmospheric pressure ionization mass spectrometry. Graphical Abstract.

  11. Study of some chaotic inflationary models in f(R) gravity

    Science.gov (United States)

    Sharif, M.; Nawazish, Iqra

    2018-04-01

    In this paper, we discuss an inflationary scenario via scalar field and fluid cosmology for an anisotropic homogeneous universe model in f(R) gravity. We consider an equation of state which corresponds to a quasi-de Sitter expansion and investigate the effect of the anisotropy parameter for different values of the deviation parameter. We evaluate potential models like linear, quadratic and quartic models which correspond to chaotic inflation. We construct the observational parameters for a power-law model of f(R) gravity and construct the graphical analysis of tensor-scalar ratio and spectral index which indicates the consistency of these parameters with Planck 2015 data.

  12. Revisiting van der Waals like behavior of f(R AdS black holes via the two point correlation function

    Directory of Open Access Journals (Sweden)

    Jie-Xiong Mo

    2017-05-01

    Full Text Available Van der Waals like behavior of f(R AdS black holes is revisited via two point correlation function, which is dual to the geodesic length in the bulk. The equation of motion constrained by the boundary condition is solved numerically and both the effect of boundary region size and f(R gravity are probed. Moreover, an analogous specific heat related to δL is introduced. It is shown that the T−δL graphs of f(R AdS black holes exhibit reverse van der Waals like behavior just as the T−S graphs do. Free energy analysis is carried out to determine the first order phase transition temperature T⁎ and the unstable branch in T−δL curve is removed by a bar T=T⁎. It is shown that the first order phase transition temperature is the same at least to the order of 1010 for different choices of the parameter b although the values of free energy vary with b. Our result further supports the former finding that charged f(R AdS black holes behave much like RN-AdS black holes. We also check the analogous equal area law numerically and find that the relative errors for both the cases θ0=0.1 and θ0=0.2 are small enough. The fitting functions between log⁡|T−Tc| and log⁡|δL−δLc| for both cases are also obtained. It is shown that the slope is around 3, implying that the critical exponent is about 2/3. This result is in accordance with those in former literatures of specific heat related to the thermal entropy or entanglement entropy.

  13. Evaluating item endorsement rates for the MMPI-2-RF F-r and Fp-r scales across ethnic, gender, and diagnostic groups with a forensic inpatient sample.

    Science.gov (United States)

    Glassmire, David M; Jhawar, Amandeep; Burchett, Danielle; Tarescavage, Anthony M

    2017-05-01

    The Minnesota Multiphasic Personality Inventory-2 (MMPI-2) F(p) (Infrequency-Psychopathology) scale was developed to measure overreporting in a manner that was minimally confounded by genuine psychopathology, which was a problem with using the MMPI-2 F (Infrequency) scale among patients with severe mental illness. Although revised versions of both of these scales are included on the MMPI-2-Restructured Form and used in a forensic context, no item-level research has been conducted on their sensitivity to genuine psychopathology among forensic psychiatric inpatients. Therefore, we examined the psychometric properties of the scales in a sample of 438 criminally committed forensic psychiatric inpatients who were adjudicated as not guilty by reason of insanity and had no known incentive to overreport. We found that 20 of the 21 Fp-r items (95.2%) demonstrated endorsement rates ≤ 20%, with 14 of the items (66.7%) endorsed by less than 10% of the sample. Similar findings were observed across genders and across patients with mood and psychotic disorders. The one item endorsed by more than 20% of the sample had a 23.7% overall endorsement rate and significantly different endorsement rates across ethnic groups, with the highest endorsements occurring among Hispanic/Latino (43.3% endorsement rate) patients. Endorsement rates of F-r items were generally higher than for Fp-r items. At the scale level, we also examined correlations with the Restructured Clinical Scales and found that Fp-r demonstrated lower correlations than F-r, indicating that Fp-r is less associated with a broad range of psychopathology. Finally, we found that Fp-r demonstrated slightly higher specificity values than F-r at all T score cutoffs. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  14. Seletividade de diferentes agrotóxicos usados na cultura da soja ao parasitoide de ovos Telenomus remus Selectivity of different pesticides used in soybean to the eggs parasitoid Telenomus remus

    Directory of Open Access Journals (Sweden)

    Eduardo Lima do Carmo

    2009-11-01

    testados, 2,4-D, S-metolacloro, flumioxazina, dicloreto de paraquate + diurom, dicloreto de paraquate e glifosato (Roundup Transorb® foram seletivos. Entretanto, glifosato + imazetapir, clomazona, glifosato (Gliz®, glifosato (Roundup Ready® foram seletivos para a fase de larva e levemente nocivos (classe 2 para a fase de pupa de T. remus. Resultados semelhantes foram obtidos com os fungicidas flutriafol + tiofanato metílico, carbenzadim, trifloxistrobina + tebuconazole e azoxistrobina + ciproconazole, que foram classificados como inócuos. Tiofanato-metílico, tebuconazole e epoxiconazole + piraclostrobina foram levemente nocivos para larvas e inócuos para pupas. Inversamente, epoxiconazole e azoxistrobina foram seletivos para a fase de larva e levemente nocivos para a fase de pupa do parasitoide. Flutriafol foi classificado como levemente nocivo para ambas as fases de T. remus.Biological control agent preservation is crucial to the integrated pest management success. However, chemical control is yet useful for crop production. Thus, pesticide selectivity to beneficial insects is a feature that must always be taken into account in order to choose the best chemical. Therefore, this research studied the impact caused by different pesticides in the egg parasitoid, Telenomus remus Nixon (Hymenoptera: Scelionidae emergence, when sprayed on the larvae and pupae stage (Egg masses from 100 to 150 eggs of Spodoptera frugiperda (J.E. Smith (Lepidoptera: Noctuidae six and ten days after the parasitism, respectively. Three trials, with 11 treatments and 5 repetitions, were carried out in the laboratory with insecticides, fungicides and herbicides. Each test was carried out with 10 treatments of chemicals and water as control. All chemicals were tested at rates used in soybean crops. Eggs of S. frugiperda parasitized by T. remus, were immersed in the treatments for five seconds. After completely dry, they were placed in plastic bags until the emergence of adults of parasitoids

  15. Importprocessen för inrednings- och gåvoartiklar från USA till Finland : En handbok för företagaren

    OpenAIRE

    Smeds, Desiré; Backlund, Johanna

    2016-01-01

    Det här examensarbetet handlar om import från USA med fokus på inrednings- och gåvoartiklar. I arbetet lyfter vi steg för steg fram de delar som utgör importprocessen hela vägen från hur man hittar en pålitlig leverantör till förtullningen av produkterna här i Finland. Syftet med arbetet är att det skall kunna fungera som en handbok för företag som vill starta en småskalig importverksamhet av inrednings- och gåvoartiklar. Vi tar även upp information om import och internationell handel i a...

  16. Wormholes in viable f(R) modified theories of gravity and weak energy condition

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovic, Petar [Universitaet Hamburg, II. Institut fuer Theoretische Physik, Hamburg (Germany); Sossich, Marko [University of Zagreb, Department of Physics, Faculty of Electrical Engineering and Computing, Zagreb (Croatia)

    2015-03-01

    In this work wormholes in viable f(R) gravity models are analyzed. We are interested in exact solutions for stress-energy tensor components depending on different shape and redshift functions. Several solutions of gravitational equations for different f(R) models are examined. The solutions found imply no need for exotic material, while this need is implied in the standard general theory of relativity. A simple expression for weak energy condition (WEC) violation near the throat is derived and analyzed. High curvature regime is also discussed, as well as the question of the highest possible values of the Ricci scalar for which the WEC is not violated near the throat, and corresponding functions are calculated for several models. The approach here differs from the one that has been common since no additional assumptions to simplify the equations have been made, and the functions in f(R) models are not considered to be arbitrary functions, but rather a feature of the theory that has to be evaluated on the basis of consistency with observations for the Solar System and cosmological evolution. Therefore in this work we show that the existence of wormholes without exotic matter is not only possible in simple arbitrary f(R) models, but also in models that are in accordance with empirical data. (orig.)

  17. 75 FR 56105 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-09-15

    ... Products, Inc., 2625 South 158th Plaza, Omaha, NE 68130. Active ingredient: Bifenthrin. Proposed uses: Dogs... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0008; FRL-8843-5] Pesticide Products... announces receipt of applications to register new uses for pesticide products containing currently...

  18. Total Synthesis of (R, R, R)-gamma-Tocopherol through Cu-Catalyzed Asymmetric 1,2-Addition

    NARCIS (Netherlands)

    Wu, Zhongtao; Harutyunyan, Syuzanna R.; Minnaard, Adriaan J.

    2014-01-01

    Based on the asymmetric copper-catalyzed 1,2-addition of Grignard reagents to ketones, (R,R,R)--tocopherol has been synthesized in 36% yield over 12 steps (longest linear sequence). The chiral center in the chroman ring was constructed with 73% ee by the 1,2-addition of a phytol-derived Grignard

  19. Late-time cosmological evolution of a general class of f(R, T) gravity with minimal curvature-matter coupling

    Energy Technology Data Exchange (ETDEWEB)

    Shabani, Hamid [University of Sistan and Baluchestan, Physics Department, Faculty of Sciences, Zahedan (Iran, Islamic Republic of); Ziaie, Amir Hadi [Islamic Azad University, Department of Physics, Kahnooj Branch, Kerman (Iran, Islamic Republic of)

    2017-08-15

    In this work, we study the late-time cosmological solutions of f(R, T) = g(R) + h(-T) models assuming that the conservation of the energy-momentum tensor (EMT) is violated. We perform our analysis through constructing an autonomous dynamical system for the equations of motion. We study the stability properties of solutions via considering linear perturbations about the related equilibrium points. Moreover, we parameterize the Lagrangian by introducing the parameters m(r) and n(s). These parameters which are constructed out of the functions g(R) and h(-T) play the main role in finding the late-time behavior of the solutions. We find that there exist, in general, three classes of solutions; all models with n > 0 include a proper transition from a prolonged matter era to a de Sitter solution. Models with -0.5 < n < 0 and n{sup '} > 1, for at least a root of equation n(s) = s - 1, include an unphysical dark energy solution preceding an improper matter era. Finally, for n < -1/2 there is a transient accelerated expansion era with -1/2 < w{sup (eff)} < -1/3 before a de Sitter phase. For all cases, in order to have a long enough matter dominated epoch, the condition m{sup '} → 0{sup +} for r f(R, T) = R{sup β} + (-T){sup α} can be observationally motivating for m → 0{sup +} and -0.024 < α < 0.02 and therefore could provide a suitable setting for later investigations. (orig.)

  20. Association analysis of IL10, TNF-α and IL23R-IL12RB2 SNPs with Behçet's disease risk in Western Algeria

    Directory of Open Access Journals (Sweden)

    Ouahiba eKhaib Dit Naib

    2013-10-01

    Full Text Available Objective: We have conducted the first study of the association of interleukin (IL-10, tumor necrosis factor alpha (TNF-α and IL23R-IL12RB2 regionSNPswith Behçet's disease (BD in Western Algeria. Methods: A total of 51 BD patients and 96 unrelated controls from West region of Algeria were genotyped by direct sequencing for 11 SNPs including 2 SNPsfrom the IL10 promoter [c.-819T>C (rs1800871, c.-592A>C (rs1800872], 6 SNPs from the TNF-α promoter [c.-1211T>C (rs1799964, c.-1043C>A (rs1800630, c.-1037C>T (rs1799724, c.-556G>A (rs1800750, c.-488G>A (rs1800629 and c.-418G>A (rs361525], and 3 SNPs from the IL23R-IL12RB2 region [g.67747415A>C (rs12119179, g.67740092G>A (rs11209032 and g.67760140T>C (rs924080]. Results: The minor alleles c.-819T and c.-592A were significantly associated with BD (OR= 2.18; 95% CI 1.28-3.73, p = 0.003; whereas, there was weaker association between TNF-αpromoter SNPs or IL23R-IL12RB2 region and disease risk.Conclusion: Unlike the TNF-αand the IL23R-IL12RB2 region SNPs, the two IL10 SNPs were strongly associated with BD. The -819T, and -592A alleles and the -819TT, -819CT, and -592AA and -592CA genotypes seem to be highly involved in the risk of developing of BD in the population of Western Algeria.

  1. 78 FR 6274 - Withdrawal of Pesticide Petitions for Residues of Pesticide Chemicals in or on Various Commodities

    Science.gov (United States)

    2013-01-30

    ... announced the filing of pesticide petition (PP 4F4281) by Bayer CropScience, Research Triangle Park, North...-imidazolidinecarboxamide in or on the food commodity rapeseed (canola) at 1.0 ppm. On March 7, 2012, Bayer Crop Science... or on cucurbits (crop group 9) at 0.05 parts per million (ppm) and fruiting vegetables (crop group 8...

  2. 77 FR 74003 - Pesticides; Draft Guidance for Pesticide Registrants on Antimicrobial Pesticide Products With...

    Science.gov (United States)

    2012-12-12

    ... Insecticide, Fungicide, and Rodenticide Act (FIFRA) or are required to register pesticides. The following list... remediation, on nonporous and porous surfaces, for residual activity, for mold prevention, and in heating...

  3. Aerial pesticide application causes DNA damage in pilots from Sinaloa, Mexico.

    Science.gov (United States)

    Martínez-Valenzuela, C; Waliszewski, S M; Amador-Muñoz, O; Meza, E; Calderón-Segura, M E; Zenteno, E; Huichapan-Martínez, J; Caba, M; Félix-Gastélum, R; Longoria-Espinoza, R

    2017-01-01

    The use of pesticides in agricultural production originates residues in the environment where they are applied. Pesticide aerial application is a frequent source of exposure to pesticides by persons dedicated to agricultural practices and those living in neighboring communities of sprayed fields. The aim of the study was to assess the genotoxic effects of pesticides in workers occupationally exposed to these chemicals during their aerial application to agricultural fields of Sinaloa, Mexico. The study involved 30 pilots of airplanes used to apply pesticides via aerial application and 30 unexposed controls. Damage was evaluated through the micronucleus assay and by other nuclear abnormalities in epithelial cells of oral mucosa. The highest frequency ratios (FR) equal to 269.5 corresponded to binucleated cells followed by 54.2, corresponding to cells with pyknotic nuclei, 45.2 of cells with chromatin condensation, 3.7 of cells with broken-egg, 3.6 of cells with micronucleus, and 2.0 of karyolytic cells. Age, worked time, smoking, and alcohol consumption did not have significant influence on nuclear abnormalities in the pilots studied. Pesticide exposure was the main factor for nuclear abnormality results and DNA damage. Marked genotoxic damage was developed even in younger pilots with 2 years of short working period, caused by their daily occupational exposure to pesticides.

  4. Pärimuslik ajalugu ja Fr. R. Kreutzwald / Tiiu Jaago

    Index Scriptorium Estoniae

    Jaago, Tiiu, 1960-

    2005-01-01

    Pärimuslik ajalugu kui rahvapärane ajalookäsitus, mida saab uurida folkloorse jutustamise kaudu. Fr. R. Kreutzwaldi ja F. K. H. Kruse sõnavõttudest Aruküla koobaste päritolu kohta ajakirjas "Das Inland" aastast 1844

  5. IL-1R and MyD88 signalling in CD4+ T cells promote Th17 immunity and atherosclerosis.

    Science.gov (United States)

    Engelbertsen, Daniel; Rattik, Sara; Wigren, Maria; Vallejo, Jenifer; Marinkovic, Goran; Schiopu, Alexandru; Björkbacka, Harry; Nilsson, Jan; Bengtsson, Eva

    2018-01-01

    The role of CD4+ T cells in atherosclerosis has been shown to be dependent on cytokine cues that regulate lineage commitment into mature T helper sub-sets. In this study, we tested the roles of IL-1R1 and MyD88 signalling in CD4+ T cells in atherosclerosis. We transferred apoe-/-myd88+/+ or apoe-/-myd88-/- CD4+ T cells to T- and B-cell-deficient rag1-/-apoe-/- mice fed high fat diet. Mice given apoe-/-myd88-/- CD4+ T cells exhibited reduced atherosclerosis compared with mice given apoe-/-myd88+/+ CD4+ T cells. CD4+ T cells from apoe-/-myd88-/- produced less IL-17 but similar levels of IFN-γ. Treatment of human CD4+ T cells with a MyD88 inhibitor inhibited IL-17 secretion in vitro. Transfer of il1r1-/- CD4+ T cells recapitulated the phenotype seen by transfer of myd88-/- CD4+ T cells with reduced lesion development and a reduction in Th17 and IL-17 production compared with wild type CD4+ T cell recipients. Relative collagen content of lesions was reduced in mice receiving il1r1-/- CD4+ T cells. We demonstrate that both IL1R and MyD88 signalling in CD4+ T cells promote Th17 immunity, plaque growth and may regulate plaque collagen levels. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions please email: journals.permissions@oup.com.

  6. Dynamical analysis of cylindrically symmetric anisotropic sources in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Zubair, M.; Azmat, Hina [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); Noureen, Ifra [University of Management and Technology, Department of Mathematics, Lahore (Pakistan)

    2017-03-15

    In this paper, we have analyzed the stability of cylindrically symmetric collapsing object filled with locally anisotropic fluid in f(R, T) theory, where R is the scalar curvature and T is the trace of stress-energy tensor of matter. Modified field equations and dynamical equations are constructed in f(R, T) gravity. The evolution or collapse equation is derived from dynamical equations by performing a linear perturbation on them. The instability range is explored in both the Newtonian and the post-Newtonian regimes with the help of an adiabatic index, which defines the impact of the physical parameters on the instability range. Some conditions are imposed on the physical quantities to secure the stability of the gravitating sources. (orig.)

  7. 75 FR 16109 - Antimicrobial Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-03-31

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2009-0936; FRL-8806-9] Antimicrobial Pesticide...: This notice announces receipt of applications to register new antimicrobial pesticide products... identified. II. Registration Applications EPA received applications as follows to register new antimicrobial...

  8. A 615 m.y. age of the Bleida granodiorite, and its implications to the chronology of Panafrican tectonic, metamorphic and magmatic phases in the Moroccan Anti-Atlas

    International Nuclear Information System (INIS)

    Ducrot, Jean

    1979-01-01

    A 615+-12 m.y. age is obtained by U-Pb method on zircons extracted from the granodiorite of Bleida (Anti-Atlas, Morocco). This age which is in good agreement with U-Pb and Rb-Sr previous data, argues for the occurrence of the panafrican orogeny in the Anti-Atlas and contributes to define the chronology of the typical features of this orogenic belt [fr

  9. 75 FR 30829 - Antimicrobial Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-06-02

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0325; FRL-8824-2] Antimicrobial Pesticide...: This notice announces receipt of an application to register new antimicrobial pesticide products... telephone number is (703) 305-5805. FOR FURTHER INFORMATION CONTACT: Demson Fuller, Antimicrobials Division...

  10. Från outsiderfilmmakare till etablerad indieregissör : David Lynch, Jim Jarmusch och Steven Soderbergh

    OpenAIRE

    Simberg, Maximilian

    2014-01-01

    Det här arbetet behandlar kreativ frihet och konstnärligt oberoende i filmskapande, utgående från begreppet independent film och regissörerna David Lynch, Jim Jarmusch och Steven Soderbergh. Den centrala frågeställningen är hur det har varit möjligt för en filmkonstnär att uppnå konstnärligt oberoende och samtidigt ha en långlivad och framgångsrik karriär. Arbetets fokus ligger på de tre regissörernas genombrottsfilmer; Eraserhead, Stranger Than Paradise och sex, lies, and videotape, och förs...

  11. New proposal for non-linear ghost-free massive F(R) gravity: Cosmic acceleration and Hamiltonian analysis

    International Nuclear Information System (INIS)

    Klusoň, Josef; Nojiri, Shin'ichi; Odintsov, Sergei D.

    2013-01-01

    We propose new version of massive F(R) gravity which is natural generalization of convenient massive ghost-free gravity. Its Hamiltonian formulation in scalar-tensor frame is developed. We show that such F(R) theory is ghost-free. The cosmological evolution of such theory is investigated. Despite the strong Bianchi identity constraint the possibility of cosmic acceleration (especially, in the presence of cold dark matter) is established. Ghost-free massive F(R,T) gravity is also proposed

  12. 41 CFR 301-11.10 - Am I required to record departure/arrival dates and times on my travel claim?

    Science.gov (United States)

    2010-07-01

    ... departure/arrival dates and times on my travel claim? 301-11.10 Section 301-11.10 Public Contracts and... dates and times on my travel claim? You must record the date of departure from, and arrival at, the... visited. You do not have to record departure/arrival times, but you must annotate your travel claim when...

  13. Pesticide exposure - Indian scene

    International Nuclear Information System (INIS)

    Gupta, P.K.

    2004-01-01

    Use of pesticides in India began in 1948 when DDT was imported for malaria control and BHC for locust control. India started pesticide production with manufacturing plant for DDT and benzene hexachloride (BHC) (HCH) in the year 1952. In 1958, India was producing over 5000 metric tonnes of pesticides. Currently, there are approximately 145 pesticides registered for use, and production has increased to approximately 85,000 metric tonnes. Rampant use of these chemicals has given rise to several short-term and long-term adverse effects of these chemicals. The first report of poisoning due to pesticides in India came from Kerala in 1958 where, over 100 people died after consuming wheat flour contaminated with parathion. Subsequently several cases of pesticide-poisoning including the Bhopal disaster have been reported. Despite the fact that the consumption of pesticides in India is still very low, about 0.5 kg/ha of pesticides against 6.60 and 12.0 kg/ha in Korea and Japan, respectively, there has been a widespread contamination of food commodities with pesticide residues, basically due to non-judicious use of pesticides. In India, 51% of food commodities are contaminated with pesticide residues and out of these, 20% have pesticides residues above the maximum residue level values on a worldwide basis. It has been observed that their long-term, low-dose exposure are increasingly linked to human health effects such as immune-suppression, hormone disruption, diminished intelligence, reproductive abnormalities, and cancer. In this light, problems of pesticide safety, regulation of pesticide use, use of biotechnology, and biopesticides, and use of pesticides obtained from natural plant sources such as neem extracts are some of the future strategies for minimizing human exposure to pesticides

  14. Solar System constraints on a cosmologically viable f(R) theory

    Energy Technology Data Exchange (ETDEWEB)

    Bisabr, Yousef, E-mail: y-bisabr@srttu.ed [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, Tehran 16788 (Iran, Islamic Republic of)

    2010-01-18

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from LAMBDACDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  15. Direct and indirect exogenous contamination by pesticides of rice-farming soils in a Mediterranean wetland.

    Science.gov (United States)

    Gamón, M; Sáez, E; Gil, J; Boluda, R

    2003-02-01

    It is known that the sources of soil contamination can be endogenous or exogenous and that exogenous contamination may be direct or indirect. In this work, an environmental pesticide fate study was conducted in soil profiles collected from 23 rice field sites in an important Mediterranean wetland (Albufera Natural Park, Valencia, Spain) from April 1996 to November 1997. Temporal and spatial distribution of 44 pesticide residues in an alluvial Mediterranean soil (gleyic-calcaric Fluvisol, Fluvaquent) were monitored. During this period, the levels of pesticide residues in different soil horizons (Ap1 0-12 cm, Ap2 12-30 cm, ApCg 30-50 cm, C1gr 50-76 cm, and C2r 76-100 cm) were investigated. In addition, information was collected on agricultural pesticide application practices and soil characteristics. Distribution throughout the soil profile showed that pesticide concentrations were always higher in the topsoil (Ap1 horizon), in the autumn season, and in the border with citrus-vegetable orchard soils (calcaric Fluvisol, Xerofluvent). Chlorpyrifos (organophosphorus), endosulfan (organochlorine), and pyridaphenthion (organophosphorus) insecticides were, respectively, the most detected of all the pesticides investigated. These results were associated with processes, such as nonleaching, transport by movement into surface waters, retention, volatilization, and chemical and biological degradation in the topsoil, as well as with direct and indirect exogenous contamination sources.

  16. Performance Evaluation of the MyT4 Technology for Determining ART Eligibility.

    Science.gov (United States)

    Sitoe, Nádia; Macamo, Rosa; Meggi, Bindiya; Tobaiwa, Ocean; Loquiha, Osvaldo; Bollinger, Timothy; Vojnov, Lara; Jani, Ilesh

    2016-01-01

    In resource-limited countries, CD4 T-cell (CD4) testing continues to be used for determining antiretroviral therapy (ART) initiation eligibility and opportunistic infection monitoring. To support expanded access to CD4 testing, simple and robust technologies are necessary. We conducted this study to evaluate the performance of a new Point-of-Care (POC) CD4 technology, the MyT4, compared to conventional laboratory CD4 testing. EDTA venous blood from 200 HIV-positive patients was tested in the laboratory using the MyT4 and BD FACSCalibur™. The MyT4 had an r2 of 0.82 and a mean bias of 12.3 cells/μl. The MyT4 had total misclassifications of 14.7% and 8.8% when analyzed using ART eligibility thresholds of 350 and 500 cells/μl, respectively. We conclude that the MyT4 performed well in classifying patients using the current ART initiation eligibility thresholds in Mozambique when compared to the conventional CD4 technology.

  17. Tier I Rice Model - Version 1.0 - Guidance for Estimating Pesticide Concentrations in Rice Paddies

    Science.gov (United States)

    Describes a Tier I Rice Model (Version 1.0) for estimating surface water exposure from the use of pesticides in rice paddies. The concentration calculated can be used for aquatic ecological risk and drinking water exposure assessments.

  18. 75 FR 13284 - Pesticide Program Dialogue Committee; Request for Nominations to the Pesticide Program Dialogue...

    Science.gov (United States)

    2010-03-19

    ... particular interest to persons who work in agricultural settings or persons who are concerned about... entities may include, but are not limited to: Agricultural workers and farmers; pesticide industry and... and special ecosystems from potential risks posed by pesticides. The Charter for EPA's PPDC was...

  19. Study of Antigravity in an F(R) Model and in Brans-Dicke Theory with Cosmological Constant

    OpenAIRE

    Oikonomou, V. K.; Karagiannakis, N.

    2014-01-01

    We study antigravity, that is having an effective gravitational constant with a negative sign, in scalar-tensor theories originating from $F(R)$-theory and in a Brans-Dicke model with cosmological constant. For the $F(R)$ theory case, we obtain the antigravity scalar-tensor theory in the Jordan frame by using a variant of the Lagrange multipliers method and we numerically study the time dependent effective gravitational constant. As we shall demonstrate by using a specific $F(R)$ model, altho...

  20. Solar System constraints on a cosmologically viable f(R) theory

    International Nuclear Information System (INIS)

    Bisabr, Yousef

    2010-01-01

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from ΛCDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  1. 75 FR 74713 - Product Cancellation Order for Certain Pesticide Registrations; Correction

    Science.gov (United States)

    2010-12-01

    ... Sergeant's Pet Care Products' pesticide product, EPA Reg. No. 2517-79. FOR FURTHER INFORMATION CONTACT: Maia Tatinclaux, Pesticide Re- evaluation Division (7508P), Office of Pesticide Programs, Environmental... hard copy, at the Office of Pesticide Programs (OPP) Regulatory Public Docket in Rm. S- 4400, One...

  2. 78 FR 26935 - Data Requirements for Antimicrobial Pesticides

    Science.gov (United States)

    2013-05-08

    ... pesticides used in conjunction with the manufacturing and processing of foods, at that time, were regulated....S.C. 136 et seq., and section 408 of the Federal Food, Drug, and Cosmetic Act (FFDCA), 21 U.S.C.... Antimicrobial pesticides are used to control microbiological contamination in healthcare applications, and...

  3. Evolved pesticide tolerance in amphibians: Predicting mechanisms based on pesticide novelty and mode of action

    International Nuclear Information System (INIS)

    Hua, Jessica; Jones, Devin K.; Mattes, Brian M.; Cothran, Rickey D.; Relyea, Rick A.; Hoverman, Jason T.

    2015-01-01

    We examined 10 wood frog populations distributed along an agricultural gradient for their tolerance to six pesticides (carbaryl, malathion, cypermethrin, permethrin, imidacloprid, and thiamethoxam) that differed in date of first registration (pesticide novelty) and mode-of-action (MOA). Our goals were to assess whether: 1) tolerance was correlated with distance to agriculture for each pesticide, 2) pesticide novelty predicted the likelihood of evolved tolerance, and 3) populations display cross-tolerance between pesticides that share and differ in MOA. Wood frog populations located close to agriculture were more tolerant to carbaryl and malathion than populations far from agriculture. Moreover, the strength of the relationship between distance to agriculture and tolerance was stronger for older pesticides compared to newer pesticides. Finally, we found evidence for cross-tolerance between carbaryl and malathion (two pesticides that share MOA). This study provides one of the most comprehensive approaches for understanding patterns of evolved tolerance in non-pest species. - Highlights: • We explored patterns of tolerance to six insecticides across 10 wood frog populations. • We found evidence that wood frogs have evolved tolerance to carbaryl and malathion. • The likelihood of evolved tolerance was stronger for older compared to newer pesticides. • We found evidence for cross-tolerance between carbaryl and malathion. • This is one of the most comprehensive approaches studying evolved tolerance in a non-pest species. - Using 10 wood frog populations, we detected evidence for evolved tolerance, found that the evolved tolerance depends on insecticide novelty, and found evidence for cross-tolerance.

  4. The wild flora biodiversity in pesticide free bufferzones along old hedgerows

    DEFF Research Database (Denmark)

    Andresen, Louise C.; Nothlev, J.; Kristensen, K.

    2012-01-01

    The natural field margin ecotone from the field border and into a cropped field hosts a diversity of plant species. In conventional cropped fields, biodiversity suffers from fertilizer and pesticide application. In our study at Danish conventional spring-barley fields, we laid out bufferzones...... with no pesticide application spraying after sowing, with the widths: 24, 12, 6 and 4 m (and control) to the field edge hedgerow. Through one season: plant species number, biodiversity and evenness for each bufferzone at the distances: 18, 9, 5, 2 and 0 m from the hedgerow were significantly affected by distance...... the bufferzone widths provided smaller biodiversity and larger evenness of plants at distances larger than the buffer width: the distance at which diversity (Shannons) was reduced by half the difference between hedge- and field diversity was 1.2, 3.1, 6.7, 10.8 and 10.9 m in bufferwidth treatments of 0, 4, 6, 12...

  5. Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR-3-hydroxymethyl-5-methyloctahydroindolizine-1,2-diol hydrobromide

    Directory of Open Access Journals (Sweden)

    Amber L. Thompson

    2009-11-01

    Full Text Available X-ray crystallographic analysis of the title hydrobromide salt, C10H20N+·Br−, of (1R,2S,3R,5R,8aR-3-hydroxymethyl-5-methyloctahydroindolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxylated indolizidine alkaloid isolated from Stevia rebaudiana (Asteraceae leaves. In the crystal structure, molecules are linked by intermolecular O—H...Br and N—H...Br hydrogen bonds, forming double chains around the twofold screw axes along the b-axis direction. Intramolecular O—H...O interactions occur.

  6. 76 FR 18906 - Mancozeb; Pesticide Tolerances

    Science.gov (United States)

    2011-04-06

    ..., 32%; cantaloupe, 12.5%; carrot, 2.5%; casaba, 12.5%; cauliflower, 15%; celery, 12%; chickpea, 2.5...%; cauliflower, 5%; celery, 12%; chickpea, 1%; Chinese waxgourd, 5%; chive, 10%; collards, 10%; corn, field, 1...%; cauliflower, 10%; chickpea, 1%; collards, 31%; corn, field, 1%; corn, sweet, 6%; cottonseed, oil, 11...

  7. Influence of f(R) models on the existence of anisotropic self-gravitating systems

    Energy Technology Data Exchange (ETDEWEB)

    Yousaf, Z.; Sharif, M.; Bhatti, M.Z. [University of the Punjab, Department of Mathematics, Lahore (Pakistan); Ilyas, M. [University of the Punjab, Centre for High Energy Physics, Lahore (Pakistan)

    2017-10-15

    This paper aims to explore some realistic configurations of anisotropic spherical structures in the background of metric f(R) gravity, where R is the Ricci scalar. The solutions obtained by Krori and Barua are used to examine the nature of particular compact stars with three different modified gravity models. The behavior of material variables is analyzed through plots and the physical viability of compact stars is investigated through energy conditions. We also discuss the behavior of different forces, equation of state parameter, measure of anisotropy and Tolman-Oppenheimer-Volkoff equation in the modeling of stellar structures. The comparison from our graphical representations may provide evidence for the realistic and viable f(R) gravity models at both theoretical and the astrophysical scale. (orig.)

  8. 78 FR 36778 - Pesticide Program Dialogue Committee; Notice of Public Meeting

    Science.gov (United States)

    2013-06-19

    ... associations; environmental, consumer, and farm worker groups; pesticide users and growers; animal rights... animal rights groups; farm worker organizations; pesticide industry and trade associations; pesticide...

  9. Constraining models of f(R) gravity with Planck and WiggleZ power spectrum data

    International Nuclear Information System (INIS)

    Dossett, Jason; Parkinson, David; Hu, Bin

    2014-01-01

    In order to explain cosmic acceleration without invoking ''dark'' physics, we consider f(R) modified gravity models, which replace the standard Einstein-Hilbert action in General Relativity with a higher derivative theory. We use data from the WiggleZ Dark Energy survey to probe the formation of structure on large scales which can place tight constraints on these models. We combine the large-scale structure data with measurements of the cosmic microwave background from the Planck surveyor. After parameterizing the modification of the action using the Compton wavelength parameter B 0 , we constrain this parameter using ISiTGR, assuming an initial non-informative log prior probability distribution of this cross-over scale. We find that the addition of the WiggleZ power spectrum provides the tightest constraints to date on B 0 by an order of magnitude, giving log 10 (B 0 ) < −4.07 at 95% confidence limit. Finally, we test whether the effect of adding the lensing amplitude A Lens and the sum of the neutrino mass ∑m ν is able to reconcile current tensions present in these parameters, but find f(R) gravity an inadequate explanation

  10. Measurement of the total reaction cross section for interactions between heavy ions (application to the system 12C+12C at 112MeV)

    International Nuclear Information System (INIS)

    Cherkaoui-Tadili, R.

    1982-01-01

    The total reaction cross-section σsub(R) for interactions between heavy ions is predicted to decrease rapidly with the energy of the incident projectile over the energy range 10 MeV/A - 100 MeV/A. We present here an experimental met σsub(R) to test the model based predictions. The method consists in counting the number of all incoming projectiles and the number of out going projectiles that did not interact with the target. The difference between these two numbers corresponds to the number of particles that reacted with the target nuclei and is therefore proportional to σsub(R). Values of σsub(R) have been measured for the system 12 C + 12 C at two incident energies of 112 MeV and 996 MeV. The results of 1444 +- 70 (112 MeV) and 994 +- 50 (996 MeV) show a total reaction cross-section decreasing with energy as predicted from the Glauber model and optical model fits to elastic scattering [fr

  11. Unified cosmic history in modified gravity: From F(R) theory to Lorentz non-invariant models

    Science.gov (United States)

    Nojiri, Shin'Ichi; Odintsov, Sergei D.

    2011-08-01

    The classical generalization of general relativity is considered as the gravitational alternative for a unified description of the early-time inflation with late-time cosmic acceleration. The structure and cosmological properties of a number of modified theories, including traditional F(R) and Hořava-Lifshitz F(R) gravity, scalar-tensor theory, string-inspired and Gauss-Bonnet theory, non-local gravity, non-minimally coupled models, and power-counting renormalizable covariant gravity are discussed. Different representations of and relations between such theories are investigated. It is shown that some versions of the above theories may be consistent with local tests and may provide a qualitatively reasonable unified description of inflation with the dark energy epoch. The cosmological reconstruction of different modified gravities is provided in great detail. It is demonstrated that eventually any given universe evolution may be reconstructed for the theories under consideration, and the explicit reconstruction is applied to an accelerating spatially flat Friedmann-Robertson-Walker (FRW) universe. Special attention is paid to Lagrange multiplier constrained and conventional F(R) gravities, for latter F(R) theory, the effective ΛCDM era and phantom divide crossing acceleration are obtained. The occurrences of the Big Rip and other finite-time future singularities in modified gravity are reviewed along with their solutions via the addition of higher-derivative gravitational invariants.

  12. Gravitational radiation in quadratic f(R) gravity

    International Nuclear Information System (INIS)

    Naef, Joachim; Jetzer, Philippe

    2011-01-01

    We investigate the gravitational radiation emitted by an isolated system for gravity theories with Lagrange density f(R)=R+aR 2 . As a formal result, we obtain leading order corrections to the quadrupole formula in general relativity. We make use of the analogy of f(R) theories with scalar-tensor theories, which in contrast to general relativity feature an additional scalar degree of freedom. Unlike general relativity, where the leading order gravitational radiation is produced by quadrupole moments, the additional degree of freedom predicts gravitational radiation of all multipoles, in particular, monopoles and dipoles, as this is the case for the most alternative gravity theories known today. An application to a hypothetical binary pulsar moving in a circular orbit yields the rough limit a 17 m 2 by constraining the dipole power to account at most for 1% of the quadrupole power as predicted by general relativity.

  13. Solar system and equivalence principle constraints on f(R) gravity by the chameleon approach

    International Nuclear Information System (INIS)

    Capozziello, Salvatore; Tsujikawa, Shinji

    2008-01-01

    We study constraints on f(R) dark energy models from solar system experiments combined with experiments on the violation of the equivalence principle. When the mass of an equivalent scalar field degree of freedom is heavy in a region with high density, a spherically symmetric body has a thin shell so that an effective coupling of the fifth force is suppressed through a chameleon mechanism. We place experimental bounds on the cosmologically viable models recently proposed in the literature that have an asymptotic form f(R)=R-λR c [1-(R c /R) 2n ] in the regime R>>R c . From the solar system constraints on the post-Newtonian parameter γ, we derive the bound n>0.5, whereas the constraints from the violations of the weak and strong equivalence principles give the bound n>0.9. This allows a possibility to find the deviation from the Λ-cold dark matter (ΛCDM) cosmological model. For the model f(R)=R-λR c (R/R c ) p with 0 -10 , which shows that this model is hardly distinguishable from the ΛCDM cosmology

  14. Study of the excited levels of 11C and 12C by the analysis of protons induced reactions

    International Nuclear Information System (INIS)

    Rihet, Y.

    1984-07-01

    The present work is a study of 11 and 12 C excited states by reactions of non polarised protons on 10 B and 11 B. R-matrix analysis of the 10 B excitation curves in the range E p = 0 to 8 MeV was used to establish parameters of 41 levels in 11 C. Isobaric multiplets of T = 1/2 and T = 3/2 states in A = 11 nuclei are deduced. Analysis of 11 B excitation curves in the E p = 0.5 to 7.4 MeV range led to parameter values of 60 levels in 12 C. T = 1 states in A = 12 isobaric nuclei are discussed [fr

  15. Détermination de quelques paramètres hématologiques chez les agriculteurs exposés aux pesticides dans la région de Tlemcen

    OpenAIRE

    SAIDI, Fatima Zohra

    2015-01-01

    Résumé Les pesticides représentent une large gamme de produits utilisés de façon très variable. Les agriculteurs sont aujourd'hui le groupe le plus exposé aux risques de contact avec les pesticides. L'objectif de notre travail consiste à mettre en évidence les altérations hématologiques chez les hommes agriculteurs disposés aux pesticides comparés aux hommes témoins. Un prélèvement sanguin est réalisé afin de déterminer quelques paramètres hématologiques (FNS, numérations cellu...

  16. Rate Processes in Dissipative Systems: 50 Years After Kramers, Discussion Meeting Held in Tutzing (Germany, F.R.) on 10-13 September 1990

    Science.gov (United States)

    1990-09-13

    Chem. Soc., Faraday Trans. [5] S. T. Abdel-Halim, M. H. Abdel-Kader, and U. E. Steiner , J. 2, 83, 1941 (1987), Phys. Chem 92, 4324 (1988). [29] W...December 5th, 1990) Zusammensetzung, Eigenschaften und Anwendungen Mesomorpher Tensidphasen RUDOLF HEUSCH Leverkusen, Paul-Klee-StraBe 85 (Received on...Institut f~r Anorganisehe Chemnie der Universitiit Rudower Chaussee 5, 0-1199 Physikalisehe Chemie) Rudolf - Bern, Freie Stra~e 3, CH-3000 Bern, be- Berlin

  17. Nanosensing of Pesticides by Zinc Oxide Quantum Dot: An Optical and Electrochemical Approach for the Detection of Pesticides in Water.

    Science.gov (United States)

    Sahoo, Dibakar; Mandal, Abhishek; Mitra, Tapas; Chakraborty, Kaushik; Bardhan, Munmun; Dasgupta, Anjan Kumar

    2018-01-17

    Present study reveals the low concentrations (∼4 ppm) of pesticide sensing vis-à-vis degradation of pesticides with the help of nontoxic zinc oxide quantum dots (QD). In our study, we have taken four different pesticides viz., aldrin, tetradifon, glyphosate, and atrazine, which are widely used in agriculture and have structural dissimilarities/diversity. By using optical sensing techniques such as steady state and time-resolved fluorescence, we have analyzed the detailed exciton dynamics of QD in the presence of different pesticides. It has been found that the pesticide containing good leaving groups (-Cl) can interact with QD promptly and has high binding affinity (∼10 7 M -1 ). The different binding signatures of QD with different pesticides enable us to differentiate between the pesticides. Time resolved fluorescence spectroscopy provides significant variance (∼150-300 ns) for different pesticides. Furthermore, a large variation (10 5 Ω to 7 × 10 4 Ω) in the resistance of QD in the presence of different pesticides was revealed by electrochemical sensing technique. Moreover, during the interaction with pesticides, QD can also act as a photocatalyst to degrade pesticides. Present investigation explored the fact that the rate of degradation is positively affected by the binding affinity, i.e., the greater the binding, the greater is the degradation. What is more, both optical and electrochemical measurements of QD, in tandem, as described in our study could be utilized as the pattern recognition sensor for detection of several pesticides.

  18. Multifunctional humate-based magnetic sorbent: Preparation, properties and sorption of Cu (II), phosphates and selected pesticides

    Czech Academy of Sciences Publication Activity Database

    Janoš, P.; Kormunda, M.; Novák, František; Životský, O.; Fuitová, J.; Pilařová, V.

    2013-01-01

    Roč. 73, č. 1 (2013), s. 46-52 ISSN 1381-5148 Grant - others:GA ČR(CZ) GAP106/12/1116 Program:GA Institutional support: RVO:60077344 Keywords : magnetic sorbent * humate-based sorbent * heavy metals * phosphate * pesticides Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.822, year: 2013

  19. 41 CFR 302-10.200 - What costs are allowable when a commercial carrier transports my mobile home overland or over water?

    Science.gov (United States)

    2010-07-01

    ... when a commercial carrier transports my mobile home overland or over water? 302-10.200 Section 302-10... carrier transports my mobile home overland or over water? Your agency will allow the following costs for... State or local law. (b) When transporting over water cost must include, but not limited to the cost of...

  20. 75 FR 51043 - Pesticide Experimental Use Permit; Receipt of Application; Comment Request

    Science.gov (United States)

    2010-08-18

    ... Pollution Prevention Division (7511P), Office of Pesticide Programs, Environmental Protection Agency, 1200... tests on 10 acres or more of land or one acre or more of water. Pursuant to 40 CFR 172.11(a), the Agency..., Kansas, Kentucky, Louisiana, Maryland, Missouri, Mississippi, New Mexico, North Carolina, Oklahoma Puerto...

  1. Calibration of silicone rubber rods as passive samplers for pesticides at two different flow velocities: Modeling of sampling rates under water boundary layer and polymer control.

    Science.gov (United States)

    Martin, Alexis; Margoum, Christelle; Jolivet, Antoine; Assoumani, Azziz; El Moujahid, Bachir; Randon, Jérôme; Coquery, Marina

    2018-04-01

    There is a need to determine time-weighted average concentrations of polar contaminants such as pesticides by passive sampling in environmental waters. Calibration data for silicone rubber-based passive samplers are lacking for this class of compounds. The calibration data, sampling rate (R s ), and partition coefficient between silicone rubber and water (K sw ) were precisely determined for 23 pesticides and 13 candidate performance reference compounds (PRCs) in a laboratory calibration system over 14 d for 2 water flow velocities, 5 and 20 cm s -1 . The results showed that an in situ exposure duration of 7 d left a silicone rubber rod passive sampler configuration in the linear or curvilinear uptake period for 19 of the pesticides studied. A change in the transport mechanism from polymer control to water boundary layer control was observed for pesticides with a log K sw of approximately 3.3. The PRC candidates were not fully relevant to correct the impact of water flow velocity on R s . We therefore propose an alternative method based on an overall resistance to mass transfer model to adjust R s from laboratory experiments to in situ hydrodynamic conditions. We estimated diffusion coefficients (D s ) and thickness of water boundary layer (δ w ) as adjustable model parameters. Log D s values ranged from -12.13 to -10.07 m 2  s -1 . The estimated δ w value showed a power function correlation with water flow velocity. Environ Toxicol Chem 2018;37:1208-1218. © 2017 SETAC. © 2017 SETAC.

  2. Prevention of dependence on the internet and social networks among children aged 10 to 12 years.

    OpenAIRE

    ZEDNÍKOVÁ, Denisa

    2017-01-01

    This bachelor thesis deals with addiction on the internet and social networks of 10-12 years old children and subsequent prevention and treatment of this addiction. My goal was to determine whether there are children in this age addicted to the Internet and social networks and if so, are there any prevention programs and in worse cases, follow-up treatments. The first chapter is a theoretical part about the definition of addiction, particularly non-substance addiction to the internet and soci...

  3. Riparian buffer zones as pesticide filters of no-till crops.

    Science.gov (United States)

    Aguiar, Terencio R; Bortolozo, F R; Hansel, F A; Rasera, K; Ferreira, M T

    2015-07-01

    Several studies have pointed to the potential benefits of riparian vegetation as buffer zones for agricultural and industrial pollutants harmful to aquatic ecosystems. However, other studies have called into question its use as an ecological filter, questioning the widths and conditions for which they are effective as a filter. In this work, we have investigated the buffering capacity of the riparian one to retain pesticides in the water-saturated zone, on 27 sites composed by riparian buffer zones with different vegetation structure (woody, shrubs, or grass vegetation) and width (12, 36, and 60 m). Five pesticides were analyzed. The effectiveness of the filtering was largely influenced by the width and vegetation type of the buffer zone. In general, decreasing pesticide removal followed in this order wood > shrubs > grass. The 60 m woody buffer zone was the most effective in the removal of all the pesticides. Only atrazine was detected in this case (0.3 μg L(-1)). Furthermore, a linear correlation (R (2) > 0.97) was observed in their removal for all compounds and buffer zones studied. Thus, preserving the woody vegetation in the riparian zone is important for watershed management and groundwater quality in the no-tillage system in temperate climate.

  4. 78 FR 24094 - Azoxystrobin; Pesticide Tolerances

    Science.gov (United States)

    2013-04-24

    ... Statistics Service (USDA/NASS), proprietary market surveys, and the National Pesticide Use Database for the... 1 to the table in paragraph (a)(1); and 0 e. Revise the introductory text of paragraph (a)(2) The...

  5. United States Air Force Summer Research Program -- 1991. High School Apprenticeship Program (HSAP) Reports, Volume 12: Rome Laboratory, Arnold Engineering Development Plan

    Science.gov (United States)

    1991-12-01

    convenient document retrieval and internal voice communications system. 12-12 AFOSR High School Apprenticeship Program July 22-August 16 1991 Gene ...with the computer software packages used here at Sverdrup; Gene Smith and Gail Arnold for their aid in faxing my pay voucher every two weeks. GENERAL...10M .,.n Z~ w z .; z z ZZ r3r M z X E X 2 z Y ZiMZ . Z Z Z Z X2X Z X Z X 2 rZ Z Z W: I. I 1 It W6 hfe II 1 - -- m _ V m-! ’ =t2Csu C1 M 0 oNt - ;I

  6. 12 CFR 563b.125 - Must my board of directors adopt a plan of conversion?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Must my board of directors adopt a plan of... board of directors adopt a plan of conversion? Prior to filing an application for conversion, your board of directors must adopt a plan of conversion that conforms to §§ 563b.320 through 563b.485 and 563b...

  7. Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R study

    Science.gov (United States)

    Spaan, Suzanne; Pronk, Anjoeka; Koch, Holger M.; Jusko, Todd A.; Jaddoe, Vincent W.V.; Shaw, Pamela A.; Tiemeier, Henning M.; Hofman, Albert; Pierik, Frank H.; Longnecker, Matthew P.

    2014-01-01

    The widespread use of organophosphate (OP) pesticides has resulted in ubiquitous exposure in humans, primarily through their diet. Exposure to OP pesticides may have adverse health effects, including neurobehavioral deficits in children. The optimal design of new studies requires data on the reliability of urinary measures of exposure. In the present study, urinary concentrations of six dialkyl phosphate (DAP) metabolites, the main urinary metabolites of OP pesticides, were determined in 120 pregnant women participating in the Generation R Study in Rotterdam. Intra-class correlation coefficients (ICCs) across serial urine specimens taken at 25 weeks of pregnancy were determined to assess reliability. Geometric mean total DAP metabolite concentrations were 229 (GSD 2.2), 240 (GSD 2.1), and 224 (GSD 2.2) nmol/g creatinine across the three periods of gestation. Metabolite concentrations from the serial urine specimens in general correlated moderately. The ICCs for the six DAP metabolites ranged from 0.14 to 0.38 (0.30 for total DAPs), indicating weak to moderate reliability. Although the DAP metabolite levels observed in this study are slightly higher and slightly more correlated than in previous studies, the low to moderate reliability indicates a high degree of within-person variability, which presents challenges for designing well-powered epidemiologic studies. PMID:25515376

  8. Assesment of pesticide fluxes to surface water using Uranine in Colombia

    Science.gov (United States)

    Garcia-Santos, G.; Scheiben, D.; Diaz, J.; Leuenberger, F.; Binder, C. R.

    2009-04-01

    In the highlands of Colombia, potato farmers maximize their yields by the application of pesticides. Properly applied pesticides can significantly reduce yield loss and improve product quality; however their misuse leads to human health and environmental problems, i.e. water bodies contaminated with pesticides. Due to the lack of control regarding local pesticide use, unmeasured hydrological parameters and use of local water runoff as a drinking water supply, an assessment of the impact of agricultural practice on water quality is mandatory as first stage. In order to accomplish this, our study assesses pesticide fluxes to surface water using the tracer Uranine. The experimental area La Hoya main basin (3 km2) contains the Pantano Verde river which flows into the Teatinos river in the Boyaca region (Colombia). Some facts such as the deep soils in the area and the importance of the unsaturated zone for the sorption and degradation of pesticides suggest a lack of contaminants in groundwater. However, due to the humid conditions, steep slopes and an intensive agricultural with high pesticide use, we expect surface water to be highly contaminated. In order to assess pesticide pathways, a tracer (Uranine), detectable at very low amount was used. Four local farmers applied the tracer instead of the pesticide mixture covering a total surface of 1.2 10-2 km2. Meteorological data were measured every 15 min with one compact meteorological station installed within the basin and water flow and water sampling were obtained using an ISCO-6700 water sampler, during one week every 10 min in the outlet of Pantano Verde River. In addition, three pairs of membranes were installed down the river and collected 1 week, one month and 4 months after the experiment to measure tracer accumulation. The tracer in water was analysed using a fluorescent spectrometer. Results of this study show first variations of tracer concentration in water in La Hoya basin and constitute an initial steep in

  9. 25 CFR 256.19 - Who performs the improvements, repairs, or replacement of my dwelling?

    Science.gov (United States)

    2010-04-01

    ... my dwelling? 256.19 Section 256.19 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR... dwelling? Independent or tribal repair or construction trades persons, home building contractors, or construction companies will perform the repairs, renovation, or replacement of your dwelling. [63 FR 10134, Mar...

  10. Monte Carlo determinations of the functions Λ(r, Z), G(r, θ), g(R) and F(r, θ) for Amersham CDCS-M-type 137Cs source

    International Nuclear Information System (INIS)

    Valdez, F. Roberto Fragoso; Alvarez Romero, J. Trinidad

    2001-01-01

    The functions Λ(r, z), G(r, θ), g(r) and F(r, θ) were calculated for Amersham model CDCS-M-type 137 Cs source by means of Monte Carlo simulation using the algorithm PENELOPE. These functions are required to verify and/or to feed planning systems or directly as entrance data for the manual planning of the distribution of absorbed dose according with the recommendations of the TG 43, [1]. The values of the constant Λ (r, Z) were determined as the quotient of absorbed dose rate distribution in water and air kerma strength in 'free air' S k . The values obtained for Λ (r, Z) differ up to 3% of those reported in the literature, being very sensitive to the cutoff energy for the electrons in the interface of the source's encapsulated and water

  11. Structure of the unbound systems: 10,12Li and 13Be

    International Nuclear Information System (INIS)

    Randisi, G.

    2011-12-01

    The unbound systems 10;12 Li and 13 Be have been studied via nucleon removal from a 14 B beam of 35 MeV/nucleon. The invariant mass (decay energy) spectra were reconstructed from the measured 9;11 Li-n and 12 Be-n coincidences. Simulations, taking into account the effects of the experimental setup and the reaction, were developed. The reconstructed decay energy spectra were interpreted using theoretical lineshapes folded with the experimental response, as well as uncorrelated distributions obtained from the data by event mixing. In the case of 10 Li, the data were reproduced with an s-wave virtual state of scattering length a s = [-10 -3 +1 (stat) ±3 (syst)] fm and l = 1 resonance with energy E r = [0.55 ± 0.02 (stat) ± 0.05 (syst)] MeV and with Γ 0 = [0.35 ± 0.05 (stat) ± 0.15 (syst)] MeV confirming the ν1p 1/2 - ν2s 1/2 inversion. For 12 Li, evidence was found for excited states between 0.2 and 0.8 MeV above the threshold. In the case of 13 Be, the decay energy, as well as the other observables, were reproduced assuming an l = 0 resonance with E r = [0.70 ± 0.05 (stat) ± 0.07 (syst)] MeV and Γ 0 = [1.7 ± 0.1 (stat) ± 0.1 (syst)] MeV and l = 2 resonance with E r = [2.4 ± 0.1(stat) ± 0.1 (syst)] MeV and Γ 0 = [0.6 ± 0.2 (stat) ± 0.1 (syst)] MeV. This hypothesis is supported by the selectivity of proton knockout, whereby the neutron configuration of the states populated in 13 Be should directly reflect that of 14 B. (author)

  12. Using measured octanol-air partition coefficients to explain environmental partitioning of organochlorine pesticides.

    Science.gov (United States)

    Shoeib, Mahiba; Harner, Tom

    2002-05-01

    Octanol-air partition coefficients (Koa) were measured directly for 19 organochlorine (OC) pesticides over the temperature range of 5 to 35 degrees C. Values of log Koa at 25 degrees C ranged over three orders of magnitude, from 7.4 for hexachlorobenzene to 10.1 for 1,1-dichloro-2,2-bis(p-chlorophenyl) ethane. Measured values were compared to values calculated as KowRT/H (where R is the ideal gas constant [8.314 J mol(-1) K(-1)], T is absolute temperature, and H is Henry's law constant) were, in general, larger. Discrepancies of up to three orders of magnitude were observed, highlighting the need for direct measurements of Koa. Plots of Koa versus inverse absolute temperature exhibited a log-linear correlation. Enthalpies of phase transition between octanol and air (deltaHoa) were determined from the temperature slopes and were in the range of 56 to 105 kJ mol(-1) K(-1). Activity coefficients in octanol (gamma(o)) were determined from Koa and reported supercooled liquid vapor pressures (pL(o)), and these were in the range of 0.3 to 12, indicating near-ideal solution behavior. Differences in Koa values for structural isomers of hexachlorocyclohexane were also explored. A Koa-based model was described for predicting the partitioning of OC pesticides to aerosols and used to calculate particulate fractions at 25 and -10 degrees C. The model also agreed well with experimental results for several OC pesticides that were equilibrated with urban aerosols in the laboratory. A log-log regression of the particle-gas partition coefficient versus Koa had a slope near unity, indicating that octanol is a good surrogate for the aerosol organic matter.

  13. Pesticide Degrading Bacteria in Aquatic Environment: Bioprospecting and Evaluation of Biotechnological Potential

    Directory of Open Access Journals (Sweden)

    Daniel Rodrigues dos Santos

    2016-07-01

    Full Text Available Pesticides play an important role in the increase of productivity in agro-industry and the extensive use of these substances cause environmental, economic and social damage in time. Microbial activity is an essential part in the dynamics and the destination of pesticides in the environment. This research focuses in prospecting and characterizing bacterial strains which are potentially able to degrade/tolerate Atrazine, Chlorpyrifos, Methyl parathion and Picloram. Bacteria were isolated from water samples collected according to the degree of salinity along the Pacoti River's estuary (Ceara, located in the semi-arid region of northeastern Brazil. A total of 49 bacterial strains were isolated, all of which tolerated/ downgraded concentrations up to 200mg/L of picloram, atrazine and methyl parathion. Tested in pesticide mixtures, the percentage and tolerance level showed that 73% grew in concentrations up to 200mg/L, 17,4% tolerated/ downgraded up to 150ml/L and the remainder only grew in concentrations under 100ml/L. The strains which had the best performance against pesticides, by points, were P1 (13Db e 14D; P2 (10E; P3 (2M, 9M, 10M, 12Mb, 14M, 17M 18Mp 19M e 20M. A high percentage of isolates (67% expressed luminescence when exposed to the pesticides atrazine and methyl parathion in concentrations between 150 and 200ml/L. DOI: http://dx.doi.org/10.17807/orbital.v8i4.748

  14. Groundwater Vulnerability Assessment to Pesticides and Their Ranking and Clustering

    Directory of Open Access Journals (Sweden)

    Ahmad Abrishamchi

    2012-10-01

    Full Text Available In this study, the different methods for groundwater vulnerability assessment to pesticides contamination and their uncertainties were introduced. Then, the groundwater vulnerability of agricultural regions of Pasha-Kolaa dam (Mazandaran province to 7 pesticides has been assessed by the mobility potential indices in the typical conditions of pesticide properties (t1/2 and KOC and the zonation maps of groundwater vulnerability in this region have been generated in the GIS environment.  According to the uncertainty of the pesticide properties and the lack of necessary data for uncertainty analysis in the region of study, the mobility potential indices in different scenarios of pesticide properties (worst and best conditions of pesticide properties (t1/2 and KOC have been calculated, mapped and zoned. The zonation maps in three scenarios (best, typical and worst conditions of pesticide properties were compared. Next, according to the regional values of mobility potential indices, generated for different scenarios, the pesticides are ranked using the composite programming method. Finally, the pesticides are clustered to three groups (suitable, transitional and unsuitable by the combination of the results of previous sections. The clustering results showed that among of studied pesticides, 2,4 D Acid, Dimethoate and Fenvalerate are suitable ,and Metsulfuron and Triclopyr are unsuitable pesticides for region of study. The other pesticides showed transitional condition.

  15. Nonlinear evolution of f(R) cosmologies. II. Power spectrum

    International Nuclear Information System (INIS)

    Oyaizu, Hiroaki; Hu, Wayne; Lima, Marcos

    2008-01-01

    We carry out a suite of cosmological simulations of modified action f(R) models where cosmic acceleration arises from an alteration of gravity instead of dark energy. These models introduce an extra scalar degree of freedom which enhances the force of gravity below the inverse mass or Compton scale of the scalar. The simulations exhibit the so-called chameleon mechanism, necessary for satisfying local constraints on gravity, where this scale depends on environment, in particular, the depth of the local gravitational potential. We find that the chameleon mechanism can substantially suppress the enhancement of power spectrum in the nonlinear regime if the background field value is comparable to or smaller than the depth of the gravitational potentials of typical structures. Nonetheless power spectrum enhancements at intermediate scales remain at a measurable level for models even when the expansion history is indistinguishable from a cosmological constant, cold dark matter model. Simple scaling relations that take the linear power spectrum into a nonlinear spectrum fail to capture the modifications of f(R) due to the change in collapsed structures, the chameleon mechanism, and the time evolution of the modifications.

  16. 76 FR 5704 - Sulfentrazone; Pesticide Tolerances

    Science.gov (United States)

    2011-02-02

    ... sulfentrazone, citing the cruelty of animal testing as the main source of opposition. The Agency has received... (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide...). UFA = extrapolation from animal to human (interspecies). UFH = potential variation in sensitivity...

  17. 78 FR 33736 - Imidacloprid; Pesticide Tolerances

    Science.gov (United States)

    2013-06-05

    ... exposure assessments of pesticides found in swimming pools and spas and EPA's Risk Assessment Guidance for... during recreational swimming, or in the case of subsistence fishermen or local Native American tribes... Order 13211, entitled ``Actions Concerning Regulations That Significantly Affect Energy Supply...

  18. 77 FR 42433 - Difenoconazole; Pesticide Tolerances

    Science.gov (United States)

    2012-07-19

    ... characteristics of difenoconazole. Further information regarding EPA drinking water models used in pesticide... exposures for which there is reliable information.'' This includes exposure through drinking water and in... States Department of Agriculture (USDA) 1994-1996 and 1998 Nationwide Continuing Surveys of Food Intake...

  19. Investigation of low spin resonances in the 12C+12C and 16O+12C systems

    International Nuclear Information System (INIS)

    Uzureau, J.L.; Fieni, J.M.; Cocu, F.; Michaudon, A.

    1979-01-01

    The excitation functions of the 12 C( 12 C,α) 20 Ne and 12 C( 16 O,α) 24 Mg reactions were measured at different angles below the Coulomb barrier. Resonant structures were found at Esub(cm)=5.80 MeV in the 12 C+ 12 C system and at Esub(cm)=6.10 MeV in the 16 O+ 12 C system. From the analysis of angular distributions measured at the previous resonant energies, values of respectively Jsup(π)=0 + and 2 + have been deduced [fr

  20. Spherically Symmetric Geometries in f(T) and f(R) Gravitational Theories

    International Nuclear Information System (INIS)

    Nashed, Gamal G. L.

    2015-01-01

    Using the well know relation between Ricci scalar, R, and torsion scalar, T, that is, R=-T-2∇_αT"α, we show that, for any spherically symmetric spacetime whose (i) scalar torsion vanishing, that is, T=T_μ_ν"αS_α"μ"ν=0 or (ii) total derivative term, that is, ∇_αT"α with T"α is the contraction of the torsion, vanishing, or (iii) the combination of scalar torsion and total derivative term vanishing, could be solution for f(T) and f(R) gravitational theories.

  1. 39 CFR 230.12 - Can Office of Inspector General employees testify or produce documents that would assist me in my...

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Can Office of Inspector General employees testify or produce documents that would assist me in my civil proceeding? 230.12 Section 230.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION OFFICE OF INSPECTOR GENERAL Rules...

  2. Degradation and persistence of cotton pesticides in sandy loam soils from Punjab, Pakistan.

    Science.gov (United States)

    Tariq, Muhammad Ilyas; Afzal, Shahzad; Hussain, Ishtiaq

    2006-02-01

    The present study evaluated the influence of temperature, moisture, and microbial activity on the degradation and persistence of commonly used cotton pesticides, i.e., carbosulfan, carbofuran, lambda-cyhalothrin, endosulfan, and monocrotophos, with the help of laboratory incubation and lysimeter studies on sandy loam soil (Typic Ustocurepts) in Pakistan. Drainage from the lysimeters was sampled on days 49, 52, 59, 73, 100, 113, and 119 against the pesticide application on days 37, 63, 82, 108, and 137 after the sowing of cotton. Carbofuran, monocrotophos, and nitrate were detected in the drainage samples, with an average value, respectively, of 2.34, 2.6 microg/L, and 15.6 mg/L for no-tillage and 2.16, 2.3 microg/L, and 13.4 mg/L for tillage. In the laboratory, pesticide disappearance kinetics were measured with sterile and nonsterile soils from 0 to 10 cm in depth at 15, 25, and 35 degrees C and 50% and 90% field water capacities. Monocrotophos and carbosulfan dissipation followed first-order kinetics while others followed second-order kinetics. The results of incubation studies showed that temperature and moisture contents significantly reduced the t(1/2) (half-life) values of pesticides in sterile and nonsterile soil, but the effect of microbial activity was nearly significant that might be due to less organic carbon (0.3%). The presence of carbofuran and monocrotophos in the soil profile (0-10, 10-30, 30-60, 60-90, 90-150 cm) and the higher concentrations of endosulfan and lambda-cyhalothrin in the top layer (0-10 cm) showed the persistence of the pesticides. The detection of endosulfan and lambda-cyhalothrin in the 10-30 cm soil layer might be due to preferential flow. The data generated from this study could be helpful for risk assessment studies of pesticides and for validating pesticide transport models for sandy loam soils in cotton-growing areas of Pakistan.

  3. Reduction of substituted benzonitrile pesticides

    Czech Academy of Sciences Publication Activity Database

    Sokolová, Romana; Hromadová, Magdaléna; Fiedler, Jan; Pospíšil, Lubomír; Giannarelli, S.; Valášek, Michal

    2008-01-01

    Roč. 622, č. 2 (2008), s. 211-218 ISSN 1572-6657 R&D Projects: GA AV ČR IAA400400505; GA MŠk OC 140; GA MŠk LC510 Institutional research plan: CEZ:AV0Z40400503; CEZ:AV0Z40550506 Keywords : benzonitrile pesticides * polarography * voltammetry Subject RIV: CG - Electrochemistry Impact factor: 2.484, year: 2008

  4. The effects of carbamate pesticide on fish in freshwater ecosystems ...

    African Journals Online (AJOL)

    The effects of carbamate pesticide on fish in freshwater ecosystems: A review. ... organisms associated with uncontrolled use of pesticides in agriculture and other ... 85R and used in controlling soil insects and many insect pests of cash crops.

  5. Generic f(R) theories and classicality of their scalarons

    Energy Technology Data Exchange (ETDEWEB)

    Gannouji, Radouane [Department of Physics, Faculty of Science, Tokyo University of Science, 1-3, Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan); Sami, M., E-mail: samijamia@gmail.com [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Thongkool, I. [Harish-Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad-211019 (India)

    2012-09-19

    We study quantum stability bound on the mass of scalaron in generic theories of f(R) gravity. We show that in these scenarios, the scalaron mass increases faster with local density of the environment than one-loop quantum correction to it thereby leading to violation of quantum bound on the chameleon mass. The introduction of quadratic curvature corrections in the action are shown to stabilize the model.

  6. 78 FR 40017 - Ethalfluralin; Pesticide Tolerances

    Science.gov (United States)

    2013-07-03

    ... (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide manufacturing (NAICS code 32532). B. How... system. Additionally, ethalfluralin does not belong to a class of chemicals (e.g., the organotins, heavy... Alimentarius is a joint United Nations Food and Agriculture Organization/World Health Organization food...

  7. 75 FR 17566 - Flutolanil; Pesticide Tolerances

    Science.gov (United States)

    2010-04-07

    ... ppm, and the greater tolerance value is needed to accommodate indirect residues from soybean..., and soybean hay at 2.5 ppm are being revoked since the same tolerance values are being established...; Pesticide Tolerances AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: This...

  8. 77 FR 73951 - Pyriproxyfen; Pesticide Tolerances

    Science.gov (United States)

    2012-12-12

    ... and was negative in the dermal sensitization study in guinea pigs. Based on repeated dose studies in... determine whether this document applies to them. Potentially affected entities may include: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide...

  9. Household pesticide usage in the United States.

    Science.gov (United States)

    Savage, E P; Keefe, T J; Wheeler, H W; Mounce, L; Helwic, L; Applehans, F; Goes, E; Goes, T; Mihlan, G; Rench, J; Taylor, D K

    1981-01-01

    A total of 10,000 U.S. households in 25 standard metropolitan statistical areas and 25 counties were included in the United States. More than 8,200 households granted an interview. Nine of every ten households in the United States used some types of pesticide in their house, garden, or yard. Households in the southeastern United States used the most pesticides. Although more than 500 different pesticide formulations were used by the sampled households, 15 pesticides accounted for 65.5% of all pesticides reported in this study. Thirteen of these 15 pesticides were insecticides, one was a herbicide, and one was a rodenticide.

  10. 76 FR 63298 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2011-10-12

    ... each contact person is: Biopesticides and Pollution Prevention Division, Office of Pesticide Programs...: October 3, 2011. Keith A Matthews, Director, Biopesticides and Pollution Prevention Division, Office of...

  11. 75 FR 6656 - Pesticide Product; Registration Application

    Science.gov (United States)

    2010-02-10

    ... (703) 305-5805. FOR FURTHER INFORMATION CONTACT: Shanaz Bacchus, Biopesticides and Pollution Prevention... protection, Pesticides and pests. Dated: January 29, 2010. Keith A. Matthews, Acting Director, Biopesticides...

  12. Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors.

    Directory of Open Access Journals (Sweden)

    Mirjam E Belderbos

    Full Text Available Human neonates are highly susceptible to infection, which may be due in part to impaired innate immune function. Neonatal Toll-like receptor (TLR responses are biased against the generation of pro-inflammatory/Th1-polarizing cytokines, yet the underlying mechanisms are incompletely defined. Here, we demonstrate that neonatal plasma polarizes TLR4-mediated cytokine production. When exposed to cord blood plasma, mononuclear cells (MCs produced significantly lower TLR4-mediated IL-12p70 and higher IL-10 compared to MC exposed to adult plasma. Suppression by neonatal plasma of TLR4-mediated IL-12p70 production, but not induction of TLR4-mediated IL-10 production, was maintained up to the age of 1 month. Cord blood plasma conferred a similar pattern of MC cytokine responses to TLR3 and TLR8 agonists, demonstrating activity towards both MyD88-dependent and MyD88-independent agonists. The factor causing increased TLR4-mediated IL-10 production by cord blood plasma was heat-labile, lost after protein depletion and independent of lipoprotein binding protein (LBP or soluble CD14 (sCD14. The factor causing inhibition of TLR4-mediated IL-12p70 production by cord blood plasma was resistant to heat inactivation or protein depletion and was independent of IL-10, vitamin D and prostaglandin E2. In conclusion, human neonatal plasma contains at least two distinct factors that suppress TLR4-mediated IL-12p70 production or induce IL-10 or production. Further identification of these factors will provide insight into the ontogeny of innate immune development and might identify novel targets for the prevention and treatment of neonatal infection.

  13. Neonatal Plasma Polarizes TLR4-Mediated Cytokine Responses towards Low IL-12p70 and High IL-10 Production via Distinct Factors

    Science.gov (United States)

    Belderbos, Mirjam E.; Levy, Ofer; Stalpers, Femke; Kimpen, Jan L.; Meyaard, Linde; Bont, Louis

    2012-01-01

    Human neonates are highly susceptible to infection, which may be due in part to impaired innate immune function. Neonatal Toll-like receptor (TLR) responses are biased against the generation of pro-inflammatory/Th1-polarizing cytokines, yet the underlying mechanisms are incompletely defined. Here, we demonstrate that neonatal plasma polarizes TLR4-mediated cytokine production. When exposed to cord blood plasma, mononuclear cells (MCs) produced significantly lower TLR4-mediated IL-12p70 and higher IL-10 compared to MC exposed to adult plasma. Suppression by neonatal plasma of TLR4-mediated IL-12p70 production, but not induction of TLR4-mediated IL-10 production, was maintained up to the age of 1 month. Cord blood plasma conferred a similar pattern of MC cytokine responses to TLR3 and TLR8 agonists, demonstrating activity towards both MyD88-dependent and MyD88-independent agonists. The factor causing increased TLR4-mediated IL-10 production by cord blood plasma was heat-labile, lost after protein depletion and independent of lipoprotein binding protein (LBP) or soluble CD14 (sCD14). The factor causing inhibition of TLR4-mediated IL-12p70 production by cord blood plasma was resistant to heat inactivation or protein depletion and was independent of IL-10, vitamin D and prostaglandin E2. In conclusion, human neonatal plasma contains at least two distinct factors that suppress TLR4-mediated IL-12p70 production or induce IL-10 or production. Further identification of these factors will provide insight into the ontogeny of innate immune development and might identify novel targets for the prevention and treatment of neonatal infection. PMID:22442690

  14. Using Noether symmetries to specify f(R) gravity

    International Nuclear Information System (INIS)

    Paliathanasis, Andronikos

    2013-01-01

    A detailed study of the modified gravity, f(R) models is performed, using the fact that the Noether point symmetries of these models are geometric symmetries of the mini su-perspace of the theory. It is shown that the requirement that the field equations admit Noether point symmetries selects definite models in a self-consistent way. As an application in Cosmology we consider the Friedman -Robertson-Walker spacetime and show that the only cosmological model which is integrable via Noether point symmetries is the (R b − 2Λ) c model, which generalizes the Lambda Cosmology. Furthermore using the corresponding Noether integrals we compute the analytic form of the main cosmological functions

  15. 76 FR 17644 - Pesticide Product; Registration Application

    Science.gov (United States)

    2011-03-30

    ... telephone number is (703) 305-5805. FOR FURTHER INFORMATION CONTACT: Gina Casciano, Biopesticides and... Environmental protection, Pesticides and pest. Dated: March 18, 2011. Keith A. Matthews, Director, Biopesticides...

  16. Bifenthrin inhibits neurite outgrowth in differentiating PC12 cells.

    Science.gov (United States)

    Tran, Van; Hoffman, Natalie; Mofunanaya, Adaobi; Pryor, Stephen C; Ojugbele, Olutosin; McLaughlin, Ashlea; Gibson, Lydia; Bonventre, Josephine A; Flynn, Katherine; Weeks, Benjamin S

    2006-02-01

    Bifenthrin is a third generation member of the synthetic pyrethroid family of insecticides. As a new pesticide within a relatively new class of pesticides, bifenthrin is considered relatively safe. Here, we used the PC12 neuronal cell line to examine the effect of bifenthrin on the formation of neurites and the potential developmental neurotoxicity of this pesticide. PC12 cells were exposed to varying concentrations of technical grade bifenthrin or Ortho Home Defense. Cell viability was determined using the AlmarBlue Toxicity Assay. Nontoxic concentrations of these chemicals were concomitantly with nerve growth factor and neurite outgrowth was assessed. Ortho Home Defense preparation reduced PC12 cell viability by approximately 50% and 70% at dilutions that correlate to bifenthrin concentrations of 10(-5) M and 10(-4) M, respectively. In contrast, technical grade bifenthrin, was not toxic to PC12 cells at 10(-3) M, which was the highest concentration tested that was soluble. At "nontoxic" concentrations of 10(-7) M and 10(-6) M, the Ortho Home Defense inhibited nerve growth factor-mediated neurite outgrowth by 30% and 55% respectively. Furthermore the nontoxic concentrations of technical grade bifenthrin of 10(-6) M and 10(-3) M inhibited neurite outgrowth by approximately 35% and 75% respectively. These data suggest that the toxicity of the Ortho Home Defense preparation was due to the "inert" additives in the preparation and not the bifenthrin itself. Further, these data suggest that, even in the absence of overt toxicity, bifenthrin may have deleterious effects to developing nervous system.

  17. 10 CFR 10.12 - Interview and other investigation.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Interview and other investigation. 10.12 Section 10.12... Interview and other investigation. (a) The Director, Division of Facilities and Security, Office of... the information in the possession of the NRC or may authorize an interview with the individual, if the...

  18. 77 FR 59114 - Cyazofamid; Pesticide Tolerances

    Science.gov (United States)

    2012-09-26

    ..., sod farms, seed farms, college and professional sports fields, residential and commercial lawns, and.../pesticides/trac/science/trac6a05.pdf . 4. Cumulative effects from substances with a common mechanism of... Chemistry Branch, Environmental Science Center, 701 Mapes Rd., Ft. Meade, MD 20755-5350; telephone number...

  19. 77 FR 73940 - Flubendiamide; Pesticide Tolerances

    Science.gov (United States)

    2012-12-12

    ... irritant and it is not a skin sensitizer under the conditions of the guinea pig maximization test. In the... determine whether this document applies to them. Potentially affected entities may include: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide...

  20. Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X-ray absorptiometry (DXA)

    DEFF Research Database (Denmark)

    Tinggaard, Jeanette; Wohlfahrt-Veje, C.; Husby, S

    2016-01-01

    ) at age 10-15. Prenatal pesticide exposure was associated with increased total, android, and gynoid fat% (DXA) at age 10-15 years after adjustment for sex, socioeconomic status, and puberty (all β = 0.5 standard deviation score (SDS) p ... (total fat: β = 0.7 SDS, android-gynoid ratio: β = 0.1, both p ... circumference were found. Prenatal pesticide exposure was associated with higher adolescent body fat content, including android fat deposition, independent of puberty. Girls appeared more susceptible than boys. Furthermore, the association depended on maternal and child PON1 Q192R genotype....

  1. miR-10 in development and cancer

    DEFF Research Database (Denmark)

    Lund, Anders Henrik

    2010-01-01

    The microRNA (miRNA) miR-10 family has attracted attention because of its conservation and the position of the miR-10 genes within the Hox clusters of developmental regulators. In several species, miR-10 is coexpressed with a set of Hox genes and has been found to regulate the translation of Hox ...... function to the miRNA repertoire.Cell Death and Differentiation advance online publication, 22 May 2009; doi:10.1038/cdd.2009.58....

  2. Model methodology for estimating pesticide concentration extremes based on sparse monitoring data

    Science.gov (United States)

    Vecchia, Aldo V.

    2018-03-22

    This report describes a new methodology for using sparse (weekly or less frequent observations) and potentially highly censored pesticide monitoring data to simulate daily pesticide concentrations and associated quantities used for acute and chronic exposure assessments, such as the annual maximum daily concentration. The new methodology is based on a statistical model that expresses log-transformed daily pesticide concentration in terms of a seasonal wave, flow-related variability, long-term trend, and serially correlated errors. Methods are described for estimating the model parameters, generating conditional simulations of daily pesticide concentration given sparse (weekly or less frequent) and potentially highly censored observations, and estimating concentration extremes based on the conditional simulations. The model can be applied to datasets with as few as 3 years of record, as few as 30 total observations, and as few as 10 uncensored observations. The model was applied to atrazine, carbaryl, chlorpyrifos, and fipronil data for U.S. Geological Survey pesticide sampling sites with sufficient data for applying the model. A total of 112 sites were analyzed for atrazine, 38 for carbaryl, 34 for chlorpyrifos, and 33 for fipronil. The results are summarized in this report; and, R functions, described in this report and provided in an accompanying model archive, can be used to fit the model parameters and generate conditional simulations of daily concentrations for use in investigations involving pesticide exposure risk and uncertainty.

  3. Thick brane in f(R) gravity with Palatini dynamics

    International Nuclear Information System (INIS)

    Bazeia, D.; Losano, L.; Menezes, R.; Olmo, Gonzalo J.; Rubiera-Garcia, D.

    2015-01-01

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R)=R+ϵR n , where the small parameter ϵ controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections

  4. Thick brane in f(R) gravity with Palatini dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D., E-mail: bazeia@fisica.ufpb.br; Losano, L., E-mail: losano@fisica.ufpb.br [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Menezes, R., E-mail: rmenezes@dce.ufpb.br [Departamento de Ciências Exatas, Universidade Federal da Paraíba, 58297-000, Rio Tinto, PB (Brazil); Departamento de Física, Universidade Federal de Campina Grande, 58109-970, Campina Grande, PB (Brazil); Olmo, Gonzalo J., E-mail: gonzalo.olmo@csic.es [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Departamento de Física Teórica, IFIC, Centro Mixto Universidad de Valencia-CSIC, Universidad de Valencia, 46100, Burjassot, Valencia (Spain); Rubiera-Garcia, D., E-mail: drgarcia@fc.ul.pt [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Faculdade de Ciências, Instituto de Astrofísica e Ciências do Espaço, Universidade de Lisboa, Campo Grande, 1749-016, Lisbon (Portugal); Department of Physics, Center for Field Theory and Particle Physics, Fudan University, 220 Handan Road, 200433, Shanghai (China)

    2015-11-30

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R)=R+ϵR{sup n}, where the small parameter ϵ controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections.

  5. Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line

    DEFF Research Database (Denmark)

    Long, M.; Laier, Peter; Vinggaard, Anne

    2003-01-01

    TV101L hepatoma cell lines. In comparison the results indicated that the rat H4IIE cell line is more sensitive than the human TV101L for detection of TCDD inducing AhR-CALUX activity. The pesticides iprodione, chlorpyrifos and prochloraz showed dose-dependent AhR agonistic effects in both cell lines...

  6. 77 FR 66723 - Fluazinam; Pesticide Tolerances

    Science.gov (United States)

    2012-11-07

    ... included changes in clinical chemistry (increased serum alkaline phosphatase and aspartate aminotransferase... white matter of the central nervous system was observed in subchronic and chronic studies in mice and..., including adults, youth (11 to http://www.epa.gov/pesticides/trac/science/trac6a05.pdf . 4. Cumulative...

  7. 77 FR 43524 - Acetamiprid; Pesticide Tolerances

    Science.gov (United States)

    2012-07-25

    ... the oral route of exposure and is minimally toxic via the dermal and inhalation routes of exposure. It... rats); the effects were considered to be adaptive. Other effects observed in the oral studies include... to the presence of any pesticide residues on food. The Agency understands the commenter's concerns...

  8. Occupational exposure to pesticides and respiratory health

    Directory of Open Access Journals (Sweden)

    Ali Mamane

    2015-06-01

    Full Text Available This article aims to review the available literature regarding the link between occupational exposure to pesticides and respiratory symptoms or diseases. Identification of epidemiological studies was performed using PubMed. 41 articles were included, 36 regarding agricultural workers and five regarding industry workers. Among the 15 cross-sectional studies focusing on respiratory symptoms and agricultural pesticide exposure, 12 found significant associations with chronic cough, wheeze, dyspnoea, breathlessness or chest tightness. All four studies on asthma found a relationship with occupational exposure, as did all three studies on chronic bronchitis. The four studies that performed spirometry reported impaired respiratory function linked to pesticide exposure, suggestive of either obstructive or restrictive syndrome according to the chemical class of pesticide. 12 papers reported results from cohort studies. Three out of nine found a significant relationship with increased risk of wheeze, five out of nine with asthma and three out of three with chronic bronchitis. In workers employed in pesticide production, elevated risks of chronic obstructive pulmonary disease (two studies out of three and impaired respiratory function suggestive of an obstructive syndrome (two studies out of two were reported. In conclusion, this article suggests that occupational exposure to pesticides is associated with an increased risk of respiratory symptoms, asthma and chronic bronchitis, but the causal relationship is still under debate.

  9. Atmospheric pressure gas chromatography quadrupole-time-of-flight mass spectrometry for simultaneous determination of fifteen organochlorine pesticides in soil and water.

    Science.gov (United States)

    Cheng, Zhipeng; Dong, Fengshou; Xu, Jun; Liu, Xingang; Wu, Xiaohu; Chen, Zenglong; Pan, Xinglu; Zheng, Yongquan

    2016-02-26

    In this study, the application of atmospheric pressure gas chromatography quadrupole-time-of-flight mass spectrometry (APGC-QTOF-MS) has been investigated for simultaneous determination of fifteen organochlorine pesticides in soil and water. Soft ionization of atmospheric pressure gas chromatography was evaluated by comparing with traditional more energetic electron impact ionization (EI). APGC-QTOF-MS showed a sensitivity enhancement by approximately 7-305 times. The QuEChERs (Quick, Easy, Cheap, Effective, Rugged, and Safe) method was used to pretreat the soil samples and solid phase extraction (SPE) cleanup was used for water samples. Precision, accuracy and stability experiments were undertaken to evaluate the feasibility of the method. The results showed that the mean recoveries for all the pesticides from the soil samples were 70.3-118.9% with 0.4-18.3% intra-day relative standard deviations (RSD) and 1.0-15.6% inter-day RSD at 10, 50 and 500 μg/L levels, while the mean recoveries of water samples were 70.0-118.0% with 1.1-17.8% intra-day RSD and 0.5-12.2% inter-day RSD at 0.1, 0.5 and 1.0 μg/L levels. Excellent linearity (0.9931 ≦ r(2)≤ 0.9999) was obtained for each pesticides in the soil and water matrix calibration curves within the range of 0.01-1.0mg/L. The limits of detection (LOD) for each of the 15 pesticides was less than 3.00 μg/L, while the limit of quantification (LOQ) was less than 9.99 μg/L in soil and water. Furthermore, the developed method was successfully applied to monitor the targeted pesticides in real soil and water samples. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. 77 FR 49732 - Cyprodinil; Pesticide Tolerances

    Science.gov (United States)

    2012-08-17

    .../puree (1x) and lemon/lime juice (1x) were used to modify the tolerance values. iii. Cancer. Based on the... the tolerance necessitate a higher value. Additionally, Codex has an established MRL on grape at 3 ppm...; Pesticide Tolerances AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: This...

  11. Chromosome r(10(p15.3q26.12 in a newborn child: case report

    Directory of Open Access Journals (Sweden)

    Jonasson Jon

    2009-12-01

    Full Text Available Abstract Background Ring chromosome 10 is a rare cytogenetic finding. Of the less than 10 reported cases we have found in the literature, none was characterized using high-resolution microarray analysis. Ring chromosomes are frequently unstable due to sister chromatid exchanges and mitotic failures. When mosaicism is present, the interpretation of genotype-phenotype correlations becomes extremely difficult. Results We report on a newborn girl with growth retardation, microcephaly, congenital heart defects, dysmorphic features and psychomotor retardation. Karyotyping revealed a non-mosaic apparently stable ring chromosome 10 replacing one of the normal homologues in all analyzed metaphases. High-resolution oligonucleotide microarray analysis showed a de novo approximately 12.5 Mb terminal deletion 10q26.12 -> qter and a corresponding 285 kb terminal deletion of 10pter -> p15.3. Conclusion This case demonstrates that an increased nuchal translucency thickness detected by early ultrasonography should preferably lead to not only QF-PCR for the diagnosis of Down syndrome but also karyotyping. In the future, microarray analysis, which needs further evaluation, might become the method of choice. The clinical phenotype of our patient was in agreement with that of patients with a terminal 10q deletion. For the purpose of genotype-phenotype analysis, there seems to be no need for a "ring syndrome" concept.

  12. Organochlorine Pesticides in the Ferruginous Pygmy Owl (Glaucidium brasilianum) in Chiapas, Mexico.

    Science.gov (United States)

    Arrona-Rivera, Alicia E; Enríquez, Paula L; García-Feria, Luis M; Orellana, Sergio Alvarado; von Osten, Jaime Rendón

    2016-09-01

    Concentrations of organochlorine pesticides were quantified in samples of feathers (n = 17) and blood (n = 15) of the ferruginous pygmy owl (Glaucidium brasilianum). The individuals were captured near the Protected Natural Area Cerro Sonsonate, Chiapas, Mexico, between February and June 2014. In both tissues, pesticides belonging to seven organochlorine chemical families were detected. However, the organochlorine pesticide concentrations differed between feathers and blood. The highest concentrations of hexachlorocyclohexanes were found in feathers (0.63 ± 0.89 μg/g), whereas the highest concentrations of ΣDrines were found in blood (0.31 ± 0.47 μg/mL). By using the summed concentrations for each of the seven families of pesticides found in feathers, we did not find any significant correlation between the pesticides and pectoral muscle or body weight (p > 0.15). The ΣDDT group was the only pesticide family that showed a positive correlation with owl body weight (r = 0.60, p = 0.05); the concentrations of these pesticides were also high in feather and blood tissues (r = 0.87, p = 0.02). Our results confirm that ferruginous pygmy owls in the study area are exposed to these pesticides.

  13. Academic Training Lecture | LHC Operation: Past and Future by Mike Lamont | 10-12 September

    CERN Multimedia

    2013-01-01

    After a successful first running period, LHC is now well into a two year shutdown for extensive consolidation. A pedagogical overview of the machine, its operating principles, its systems and underlying accelerator physics is presented. Performance past and future is discussed.   These lectures will be presented in three parts: LHC Operation: Past and Future (1/3): Tuesday 10 September 2013 from 11:00 to 12:00 at CERN (222-R-001 - Filtration Plant) LHC Operation: Past and Future (2/3): Wednesday 11 September from 11:00 to 12:00 at CERN (222-R-001 - Filtration Plant) LHC Operation: Past and Future (3/3): Thursday 12 September from 11:00 to 12:00 at CERN (222-R-001 - Filtration Plant) Click here to view the event details on Indico.

  14. Preparation of H3PW12O40/MCM-48 and its photocatalytic degradation of pesticides.

    Science.gov (United States)

    Liu, Xia; Li, Yan-zhou; Gan, Qiang; Feng, Chang-gen

    2014-08-01

    A composite catalyst H3PW12O40/MCM-48 was prepared by loading photocatalyst phosphotungstic acid H3PW12O40 (HPW) to molecular sieve MCM-48 by impregnation method, and its structure was characterized by Fourier transform infrared (FT-IR) spectra, small angle X-ray diffraction (XRD) patterns, nitrogen adsorption analysis and High-resolution transmission electron microscopy (HRTEM) analysis. Photocatalytic degradation activities of HPW/MCM-48 against pesticides imidacloprid and paraquat were evaluated under UV radiation (365 nm). The results show that HPW/MCM-48 maintains the mesoprous molecular sieve structure of MCM-48 and the Keggin structure of HPW, while the BET surface area is 793.35 m2 x g(-1), pore volume is 1.46 cm3 x g(-1), average pore diameter is 2.76 nm, suggesting loading HPW on MCM-48 is a considerable way to improve its surface area. After 14 h UV irradiation (365 nm), 57.38% imidacloprid and 63.79% paraquat were degraded by 20 mg HPW/MCM-48 catalyst, while HPW and blank group degraded the two pesticides at the degradation rate of about 25% and 5%, respectively. Implying loading on MCM-48 could greaterly improve the degradation activity of HPW. The reslut of degradation kinetics show that, the degradation process of HPW/MCM-48 fits first order kinetics equation. The rate constant Ka of HPW/MCM-48 toward imidacloprid and paraquat are 0.089 h and 0.117 h, with the half-life t(1/2) of 7.8 h and 5.9 h, respectively.

  15. Investigating the little rip and other future singularities of the universe, and validity of the second law of thermodynamics in F(R theory

    Directory of Open Access Journals (Sweden)

    M Aghaei Abchouyeh

    2015-01-01

    Full Text Available The future singularities are possible in a universe that is described by F(R theory. In previous studies the occurrence of the singularities in F(R theory have been considered by using a special function for the Hubble parameter and calculating the F(R function for each of the singularities. Using the specified Hubble parameter causes some difficulties in the study of the second law of thermodynamics. In this paper by using the scale factor, the behavior of F(R function near each type of the singularities is considered. We can check the validity of the second law of thermodynamics near the singularities. At first we study the Little Rip and then the other types of singularities are considered. The results show that the second law of thermodynamics is satisfied near the singularity type (I with some special conditions and is violated with some other conditions. it is satisfied near the Little Rip, type (II, (III and (IV singularities

  16. 75 FR 13277 - Notice of Receipt of Several Pesticide Petitions Filed for Residues of Pesticide Chemicals in or...

    Science.gov (United States)

    2010-03-19

    ... pesticide manufacturer. Potentially affected entities may include, but are not limited to: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide... compound, in or on onion, bulb, subgroup 3-07A at 0.2 ppm; onion, green, subgroup 3-07B at 9.0 ppm...

  17. Determination of selected pesticides in water samples adjacent to agricultural fields and removal of organophosphorus insecticide chlorpyrifos using soil bacterial isolates

    Science.gov (United States)

    Hossain, M. S.; Chowdhury, M. Alamgir Zaman; Pramanik, Md. Kamruzzaman; Rahman, M. A.; Fakhruddin, A. N. M.; Alam, M. Khorshed

    2015-06-01

    The use of pesticide for crops leads to serious environmental pollution, therefore, it is essential to monitor and develop approaches to remove pesticide from contaminated environment. In this study, water samples were collected to monitor pesticide residues, and degradation of chlorpyrifos was also performed using soil bacteria. Identification of pesticide residues and determination of their levels were performed by high-performance liquid chromatography with photodiode array detector. Among 12 samples, 10 samples were found contaminated with pesticides. Chlorpyrifos was detected in four tested samples and concentrations ranged from 3.27 to 9.31 μg/l whereas fenitrothion ranging from (Below Detection Limit, chlorpyrifos completely in 8, 10 and 10 days, respectively, when 20 mg/l chlorpyrifos was supplied as sole source of carbon. Whereas, BG1, BG4 and PD6 took 14, 16 and 16 days, respectively, for complete removal of 50 mg/l chlorpyrifos. Chlorpyrifos degradation rates were found maximum by all three isolates at 2nd day of incubation for both tested concentrations. The results of the present study suggest the need for regular monitoring of pesticide residues in water, to protect the aquatic environment. Chlorpyrifos degrading bacterial isolates can be used to clean up environmental samples contaminated with the organophosphate pesticides.

  18. 76 FR 61587 - Prothioconazole; Pesticide Tolerances

    Science.gov (United States)

    2011-10-05

    ... class of pesticides. Although conazoles act similarly in plants (fungi) by inhibiting ergosterol... barley at 0.2 ppm; oats, rye, and wheat at 0.05 ppm each; in the fodder (dry) of cereal grains at 5 ppm..., including barley (0.35 ppm), wheat (0.07 ppm). Harmonization of the proposed tolerances with the existing...

  19. Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers.

    Science.gov (United States)

    Chiu, Yu-Han; Williams, Paige L; Mínguez-Alarcón, Lidia; Gillman, Matthew; Sun, Qi; Ospina, Maria; Calafat, Antonia M; Hauser, Russ; Chavarro, Jorge E

    2018-01-01

    We developed a pesticide residue burden score (PRBS) based on a food frequency questionnaire and surveillance data on food pesticide residues to characterize dietary exposure over the past year. In the present study, we evaluated the association of the PRBS with urinary concentrations of pesticide biomarkers. Fruit and vegetable (FV) intake was classified as having high (PRBS≥4) or low (PRBSEARTH study. Two urine samples per man were analyzed for seven biomarkers of organophosphate and pyrethroid insecticides, and the herbicide 2,4-dichlorophenoxyacetic acid. We used generalized estimating equations to analyze the association of the PRBS with urinary concentrations of pesticide biomarkers. Urinary concentrations of pesticide biomarkers were positively related to high pesticide FV intake but inversely related to low pesticide FV intake. The molar sum of urinary concentrations of pesticide biomarkers was 21% (95% confidence interval (CI): 2%, 44%) higher for each one serving/day increase in high pesticide FV intake, and 10% (95% CI: 1%, 18%) lower for each one serving/day increase in low pesticide FV intake. Furthermore, intake of high pesticide FVs positively related to most individual urinary biomarkers. Our findings support the usefulness of the PRBS approach to characterize dietary exposure to select pesticides.

  20. The origin of high magnetic properties in (R,Zr)(Fe,Co)11.0–11.5Ti1.0–0.5Ny (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

    International Nuclear Information System (INIS)

    Kobayashi, K.; Suzuki, S.; Kuno, T.; Urushibata, K.; Sakuma, N.; Yano, M.; Shoji, T.; Kato, A.; Manabe, A.

    2017-01-01

    Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co) 11.0–11.5 Ti 1.0–0.5 N y (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn 12 -type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe 0.75 Co 0.25 ), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti 1.0 to −Ti 0.5 , which increased the Fe and Co content, preserved the ThMn 12 structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe 11 Ti 1.0 N 1.5 , and by 7% for the Co-containing, (Nd 0.7 Zr 0.3 ) (Fe 0.75 Co 0.25 ) 11.5 Ti 0.5 N 1.3 alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

  1. Brain cancer and pesticide relationship in orchard farmers of Kashmir.

    Science.gov (United States)

    Bhat, Abdul Rashid; Wani, Muhammed Afzal; Kirmani, A R

    2010-09-01

    The increasing trend in the incidence of primary malignant brain tumors in orchard farmers and their families in Kashmir. To determine the relationship between the patients of primary malignant brain tumors and their occupation. Retrospectively, case files along with death certificates of 432 patients of primary malignant brain tumors and 457 controls (non-tumor neurologic diseases), admitted for treatment simultaneously over a period of 4 years from January 2005 to December 2008, to the Neurosurgery, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Kashmir, were studied. Follow-up and family interaction was established. Analysis revealed that 90.04% (389 out of 432) patients were orchard farm workers, orchard residents and orchard playing children exposed to the high levels of multiple types of neurotoxic and carcinogenic (chlorpyriphos, dimethoate, mancozeb and captan) chemicals for more than 10 years [relative risk (RR) = 10.6; odds ratio (OR) = >10; 95% confidence interval (CI) = >25-40]. The 9.96% (43 out of 432) patients were not exposed to pesticides. On the other hand, only 19 patients out of 457 controls had recorded history of pesticide exposure and 438 were unrelated to pesticides. Out of 389 patients, 71.7% (279 out of 389) were males and 28.3% (110 out of 389), including six members of three families, were females (one male child). All orchard-related 389 patients had high-grade tumors as compared to the non-pesticide tumors. Mortality in pesticide-exposed tumors was 12%. The higher or upper-normal levels of serum cholinesterase (AChE) were observed in 54.7% (213 out of 389) patients and decreased levels were found in only 45.3% (176 out of 389) orchard-related patients (RR = 19.4; OR = >5; 95% CI = >1-10). Although serum AChE levels were a routine investigation in malignant brain tumors, this was not a routine in other neurological conditions (hospitalized controls). The familial gliomas have shown an emerging trend in the orchard residents of

  2. 40 CFR 52.870 - Identification of plan.

    Science.gov (United States)

    2010-07-01

    ... FR 1420 K.A.R. 28-19-23 Hydrocarbon Emissions—Stationary Sources 12/27/72 11/8/73, 38 FR 30876 K.A.R... Operations 10/7/91 6/23/92, 57 FR 27936 K.A.R. 28-19-77 Chemical Processing Facilities That Operate Alcohol... published 3/2/76. (7) Analysis and Recommendations Concerning Designation of Air Quality Maintenance Areas...

  3. 75 FR 16100 - Antimicrobial Pesticide Registration Review Dockets Opened for Review and Comment

    Science.gov (United States)

    2010-03-31

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0032; FRL-8810-1] Antimicrobial Pesticide.... for the pesticide of interest. For general information contact: Lance Wormell, Antimicrobials Division... have been completed. List of Subjects Environmental protection, Antimicrobials, Pesticides and pests...

  4. 78 FR 38328 - Registration Review; Pesticide Dockets Opened for Review and Comment; Announcement of...

    Science.gov (United States)

    2013-06-26

    .... Environmental justice. EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement... high and adverse human health impacts or environmental effects from exposure to the pesticide(s... registrations of pesticides are to be reviewed every 15 years. Under FIFRA, a pesticide product may be...

  5. The influence of farmer perception on pesticide usage for ...

    African Journals Online (AJOL)

    A case study conducted in eastern Uganda revealed that: (a) pesticide usage depended on farmer production goal, (b) change from one pesticide to another depended on ... Ces résults ont fermément montré que les recommendations de la gestion des pestes aux fermiers doivent prendre en considération la perception des ...

  6. Pesticides in the propolis at São Saulo State, Brazil - doi: 10.4025/actascianimsci.v34i4.15859 Pesticides in the propolis at São Saulo State, Brazil - doi: 10.4025/actascianimsci.v34i4.15859

    Directory of Open Access Journals (Sweden)

    Samir Moura Kadri

    2012-10-01

    Full Text Available The increasing demand for propolis has caused a raise in its production. However, an increasingly pesticide-dependent agriculture is a great concern with regard to bees, their produce and environmental contamination. Current analysis evaluates the presence of pesticides (organochlorines, organophosphates, pyrethroids, carbamates, herbicides, fungicides and acaricides in samples of propolis from the state of São Paulo, Brazil. Beekeepers from several localities in the state provided samples of propolis (50, which were collected, stored in non-toxic plastic bags and maintained in a freezer for analyses. Possible pesticide residues were examined by gas chromatography method but no pesticide residues were detected in the examined propolis samples. Propolis analyzed in the state of São Paulo did not show any pesticide contamination. The increasing demand for propolis has caused a raise in its production. However, an increasingly pesticide-dependent agriculture is a great concern with regard to bees, their produce and environmental contamination. Current analysis evaluates the presence of pesticides (organochlorines, organophosphates, pyrethroids, carbamates, herbicides, fungicides and acaricides in samples of propolis from the state of São Paulo, Brazil. Beekeepers from several localities in the state provided samples of propolis (50, which were collected, stored in non-toxic plastic bags and maintained in a freezer for analyses. Possible pesticide residues were examined by gas chromatography method but no pesticide residues were detected in the examined propolis samples. Propolis analyzed in the state of São Paulo did not show any pesticide contamination.

  7. Vendor-based restrictions on pesticide sales to prevent pesticide self-poisoning - a pilot study

    Directory of Open Access Journals (Sweden)

    Manjula Weerasinghe

    2018-02-01

    Full Text Available Abstract Background In South Asia, up to 20% of people ingesting pesticides for self-poisoning purchase the pesticide from a shop with the sole intention of self-harm. Individuals who are intoxicated with alcohol and/or non-farmers represent 72% of such high-risk individuals. We aimed to test the feasibility and acceptability of vendor-based restrictions on pesticide sales for such high-risk individuals. Methods We conducted a pilot study in 14 (rural = 7, urban = 7 pesticide shops in Anuradhapura District of Sri Lanka. A two-hour training program was delivered to 28 pesticide vendors; the aim of the training was to help vendors recognize and respond to customers at high risk of pesticide self-poisoning. Knowledge and attitudes of vendors towards preventing access to pesticides for self-poisoning at baseline and in a three month follow-up was evaluated by questionnaire. Vendors were interviewed to explore the practice skills taught in the training and their assessment of the program. Results The scores of knowledge and attitudes of the vendors significantly increased by 23% (95% CI 15%–32%, p < 0.001 and by 16% (95% CI 9%–23%, p < 0.001 respectively in the follow-up. Fifteen (60% vendors reported refusing sell pesticides to a high-risk person (non-farmer or intoxicated person in the follow-up compared to three (12% at baseline. Vendors reported that they were aware from community feedback that they had prevented at least seven suicide attempts. On four identified occasions, vendors in urban shops had been unable to recognize the self-harming intention of customers who then ingested the pesticide. Only 2 (8% vendors were dissatisfied with the training and 23 (92% said they would recommend it to other vendors. Conclusions Our study suggests that vendor-based sales restriction in regions with high rates of self-poisoning has the potential to reduce access to pesticides for self-poisoning. A large-scale study of the effectiveness

  8. 77 FR 68771 - Pesticide Program Dialogue Committee; Notice of Public Meeting

    Science.gov (United States)

    2012-11-16

    ... growers; animal rights groups; pest consultants; State, local, and tribal governments; academia; public.... The following sectors are represented on the current PPDC: Environmental/public interest and animal rights groups; farm worker organizations; pesticide industry and trade associations; pesticide user...

  9. A new SERS substrate based on silver nanoparticle functionalized polymethacrylate monoliths in a capillary, and it application to the trace determination of pesticides

    International Nuclear Information System (INIS)

    Pan, Yingcheng; Zhu, Jinglu; Wang, Xuan; Zhang, Han; Kang, Yan; Wu, Ting; Du, Yiping; Guo, Xiaoyu

    2015-01-01

    We have developed a simple, sensitive and practical substrate for surface enhanced Raman scattering (SERS). It consists of a column material that is obtained by modifying the surface of (glycidyl methacrylate)-co-(ethylene dimethacrylate) capillary monoliths with silver nanoparticles. This new SERS column substrate was applied to the determination of 4-mercaptopyridine (4-Mpy) and Rhodamine 6G (R6G) to give detection limits as low as 100 and 10 pM, respectively. The calculated enhancement factor is approximately 1.2 × 10 8 . This represents a substantial improvement over conventional colloidal substrates. The new substrate was applied to the determination of residues of the pesticide phosmet and gave a detection limit of 3 μg∙L −1 , with a linear response in the 3 to 1000 μg∙L −1 concentration range (R 2  = 0.995). Additionally, 0.2 mg∙kg −1 of phosmet on apples and oranges, and of 0.5 mg∙kg −1 on tea leaves were detectable via SERS using this column along with a simple extraction process. The above LODs are well below the tolerance level prescribed by National Standard of China. Thus, this simple method is highly efficient, sensitive, and affordable and introduces a SERS–based trace detection suitable for real-world applications, especially for the determination of pesticides. (author)

  10. 75 FR 23759 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-05-04

    ... classification/Use: Terrestrial food use for brassica leafy vegetables, bulb vegetables, cucurbit vegetables...%. Proposed classification/Use: Terrestrial food use for brassica leafy vegetables, bulb vegetables, cucurbit... potentially affected by this action if you are an agricultural producer, food manufacturer, or pesticide...

  11. Thin-shell wormholes with charge in F(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Eiroa, Ernesto F. [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina); Universidad de Buenos Aires, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Figueroa Aguirre, Griselda [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina)

    2016-03-15

    In this article, we construct a class of constant curvature and spherically symmetric thin-shell Lorentzian wormholes in F(R) theories of gravity and we analyze their stability under perturbations preserving the symmetry. We find that the junction conditions determine the equation of state of the matter at the throat. As a particular case, we consider configurations with mass and charge. We obtain that stable static solutions are possible for suitable values of the parameters of the model. (orig.)

  12. Thin-shell wormholes with charge in F(R) gravity

    International Nuclear Information System (INIS)

    Eiroa, Ernesto F.; Figueroa Aguirre, Griselda

    2016-01-01

    In this article, we construct a class of constant curvature and spherically symmetric thin-shell Lorentzian wormholes in F(R) theories of gravity and we analyze their stability under perturbations preserving the symmetry. We find that the junction conditions determine the equation of state of the matter at the throat. As a particular case, we consider configurations with mass and charge. We obtain that stable static solutions are possible for suitable values of the parameters of the model. (orig.)

  13. 75 FR 6656 - SFIREG Pesticide Operations and Management Working Committee Meeting

    Science.gov (United States)

    2010-02-10

    ... Evaluation Group (SFIREG), Pesticide Operations and Management (POM) Working Committee will hold a 2-day... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0001; FRL-8811-3] SFIREG Pesticide Operations and Management Working Committee Meeting AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY...

  14. The combined antiandrogenic effects of five commonly used pesticides

    DEFF Research Database (Denmark)

    Kjærstad, Mia Birkhøj; Nellemann, Christine Lydia; Jarfelt, Kirsten

    2004-01-01

    In this study, mixture effects of five dissimilarly acting pesticides were analyzed for antiandrogenic effects in vitro and in vivo. Deltamethrin, methiocarb, prochloraz, simazine, and tribenuron-methyl are all commonly used for agricultural and horticultural purposes. Concentration-response curves...... for the inhibition of R1881-induced transcriptional activity of the androgen receptor (AR) in vitro of each pesticide alone and in an equimolar mixture were obtained. The IC25 values for deltamethrin, methiocarb, prochloraz, and the mixture were 5.8, 5.8, 3.5, and 7.5 muM, respectively. Simazine and tribenuron...... of the pesticides in vitro. In vivo, each of the five pesticides and a mixture of the pesticides were tested for antiandrogenic effects in castrated testosterone-treated Wistar rats. The mixture induced a significant change of weights of the levator ani/bulbocavernosus muscle and adrenal glands. Changes in gene...

  15. Preharvest Interval Periods and their relation to fruit growth stages and pesticide formulations.

    Science.gov (United States)

    Alister, Claudio; Araya, Manuel; Becerra, Kevin; Saavedra, Jorge; Kogan, Marcelo

    2017-04-15

    The aim of this study was to evaluate the effect of pesticide formulations and fruit growth stages on the Pre-harvest Interval Period (PHI). Results showed that pesticide formulations did not affect the initial deposit and dissipation rate. However, the fruit growth stage at the application time showed a significant effect on the above-mentioned parameters. Fruit diameter increases in one millimeter pesticide dissipation rates were reduced in -0.033mgkg -1 day -1 (R 2 =0.87; p<0.001) for grapes and -0.014mgkg -1 day -1 (R 2 =0.85; p<0.001) for apples. The relation between solar radiation, air humidity and temperature, and pesticide dissipation rates were dependent on fruit type. PHI could change according to the application time, because of the initial amount of pesticide deposit in the fruits and change in the dissipation rates. Because Maximum Residue Level are becoming more restrictive, it is more important to consider the fruit growth stage effects on pesticide when performing dissipation studies to define PHI. Copyright © 2016. Published by Elsevier Ltd.

  16. Multiple stressors and amphibian declines: dual impacts of pesticides and fish on yellow-legged frogs.

    Science.gov (United States)

    Davidson, Carlos; Knapp, Roland A

    2007-03-01

    More than 40% of Earth's 5700+ amphibian species have undergone recent declines. Despite the likely involvement of multiple factors in driving these declines, most studies continue to focus on single stressors. In California (USA), separate studies have implicated either introduced fish or pesticides as causal agents. To date, however, no study has simultaneously evaluated the respective roles of these two potential stressors nor attempted to assess their relative importance, information critical for the development of effective conservation efforts and environmental policies. We examined the role and relative effect of fish and pesticides on the mountain yellow-legged frog (Rana muscosa) using unusually detailed data sets for a large portion of R. muscosa's historic range in California's Sierra Nevada. Habitat characteristics and presence/absence of R. muscosa and fish were quantified at each of 6831 sites during field surveys. Pesticide use upwind of each site was calculated from pesticide application records and predominant wind directions. Using generalized additive models, we found that, after accounting for habitat effects, the probability of R. muscosa presence was significantly reduced by both fish and pesticides, with the landscape-scale effect of pesticides much stronger than that of fish. The degree to which a site was sheltered from the predominant wind (and associated pesticides) was also a significant predictor of R. muscosa presence. Taken together, these results represent the strongest evidence to date that windborne pesticides are contributing to amphibian declines in pristine locations. Our results suggest that amphibian declines may have complex multi-factorial causes, and caution that single-factor studies that demonstrate the importance of one factor should not be used as evidence against the importance of other factors.

  17. Long-term persistence of various 14C-labeled pesticides in soils

    International Nuclear Information System (INIS)

    Jablonowski, Nicolai D.; Linden, Andreas; Köppchen, Stephan; Thiele, Björn; Hofmann, Diana; Mittelstaedt, Werner; Pütz, Thomas; Burauel, Peter

    2012-01-01

    The fate of the 14 C-labeled herbicides ethidimuron (ETD), methabenzthiazuron (MBT), and the fungicide anilazine (ANI) in soils was evaluated after long-term aging (9–17 years) in field based lysimeters subject to crop rotation. Analysis of residual 14 C activity in the soils revealed 19% (ETD soil; 0–10 cm depth), 35% (MBT soil; 0–30), and 43% (ANI soil; 0–30) of the total initially applied. Accelerated solvent extraction yielded 90% (ETD soil), 26% (MBT soil), and 41% (ANI soil) of residual pesticide 14 C activity in the samples. LC-MS/MS analysis revealed the parent compounds ETD and MBT, accounting for 3% and 2% of applied active ingredient in the soil layer, as well as dihydroxy-anilazine as the primary ANI metabolite. The results for ETD and MBT were matching with values obtained from samples of a 12 year old field plot experiment. The data demonstrate the long-term persistence of these pesticides in soils based on outdoor trials. - Highlights: ► The environmental persistence of three 14 C-labeled pesticides in soils is presented. ► Extract analysis revealed the pesticides and metabolites after 9–17 years of aging. ► Pesticide residues may represent a long-term soil burden. ► The bioaccessibility and/or bioavailability of long-term aged pesticide residues remain unknown. - Residual fractions of the pesticides ethidimuron, methabenzthiazuron, and metabolites of anilazine are highly persistent in soils and remain extractable after long-term environmental aging.

  18. 75 FR 17571 - Pendimethalin; Pesticide Tolerances

    Science.gov (United States)

    2010-04-07

    ... Enforcement Methodology Adequate enforcement methodology, using liquid chromatography/mass spectrometry... Order Reviews This final rule establishes tolerances under section 408(d) of FFDCA in response to a... actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR 51735...

  19. Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells

    International Nuclear Information System (INIS)

    Shibata, Yasuaki; Tsukazaki, Tomoo; Hirata, Kazunari; Xin Cheng; Yamaguchi, Akira

    2004-01-01

    Bone regeneration is critically regulated by various molecules. To identify the new genes involved in bone regeneration, we performed microarray-based gene expression analysis using a mouse bone regeneration model. We identified a new member of the IGFBP superfamily, designated IGFBP-rP10, whose expression is up-regulated at the early phase of bone regeneration. IGFBP-rP10 consists of an IGFBP homologous domain followed by a Kazal-type protein inhibitor domain and an immunoglobulin G-like domain. A real-time-based RT-PCR analysis demonstrated that various tissues including bone expressed IGFBP-rP10 mRNA in various degrees, and confirmed an up-regulation at the early phase of bone regeneration. In situ hybridization revealed that osteoblastic cells expressed IGFPB-rP10 mRNA during bone regeneration. Bone morphogenetic protein-2 increased the expression level of IGFBP-rP10 mRNA in various cells including C3H10T1/2, MC3T3-E1, C2C12, and primary murine osteoblastic cells. The addition of recombinant mouse IGFBP-rP10 promoted the proliferation of these cells but failed to stimulate alkaline phosphatase activity. These results suggest that IGFBP-rP10 is involved in the proliferation of osteoblasts during bone formation and bone regeneration

  20. Towards accreditation of MINT pesticide residue laboratory - a journey

    International Nuclear Information System (INIS)

    Nashriyah Mat; Salmah Moosa; Misman Sumin; Maizatul Akmam Mohd Nasir; Norimah Yusof

    2005-01-01

    The laboratory accreditation process under ISO/IEC 17025 is a complex journey, due to several compulsory inputs necessary for obtaining the accreditation. This paper dwells on most of those inputs in the context of MINT Pesticide Residue Laboratory (MPRL), including: 1) Quality work culture; 2) Management commitment; 3) Sustainability of laboratory service appointment; 4) Laboratory personnel; 5) Laboratory equipment; 6) Continual training of personnel; 7) Technical co-operation; 8) Laboratory safety; 9) Special and general budget; 10) Consultancy service; 11) Quality Manual, Procedure, Work Instruction and related documents; 12) Internal Quality Audit (IQA) by MINT Quality Unit, and 13) Teamwork spirit. Based on experience faced and knowledge gained, multiple problems arising during this journey towards MINT Pesticide Residue Laboratory accreditation are also discussed in general, including their solutions. (Author)

  1. Erosion rills offset the efficacy of vegetated buffer strips to mitigate pesticide exposure in surface waters.

    Science.gov (United States)

    Stehle, Sebastian; Dabrowski, James Michael; Bangert, Uli; Schulz, Ralf

    2016-03-01

    Regulatory risk assessment considers vegetated buffer strips as effective risk mitigation measures for the reduction of runoff-related pesticide exposure of surface waters. However, apart from buffer strip widths, further characteristics such as vegetation density or the presence of erosion rills are generally neglected in the determination of buffer strip mitigation efficacies. This study conducted a field survey of fruit orchards (average slope 3.1-12.2%) of the Lourens River catchment, South Africa, which specifically focused on the characteristics and attributes of buffer strips separating orchard areas from tributary streams. In addition, in-stream and erosion rill water samples were collected during three runoff events and GIS-based modeling was employed to predict losses of pesticides associated with runoff. The results show that erosion rills are common in buffer strips (on average 13 to 24 m wide) of the tributaries (up to 6.5 erosion rills per km flow length) and that erosion rills represent concentrated entry pathways of pesticide runoff into the tributaries during rainfall events. Exposure modeling shows that measured pesticide surface water concentrations correlated significantly (R(2)=0.626; pregulatory risk assessment procedures conducted for pesticide authorization. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Effects of currently used pesticides and their mixtures on the function of thyroid hormone and aryl hydrocarbon receptor in cell culture

    Energy Technology Data Exchange (ETDEWEB)

    Ghisari, Mandana; Long, Manhai; Tabbo, Agnese; Bonefeld-Jørgensen, Eva Cecilie, E-mail: ebj@mil.au.dk

    2015-05-01

    Evidence suggest that exposure to pesticides can interfere with the endocrine system by multiple mechanisms. The endocrine disrupting potential of currently used pesticides in Denmark was analyzed as single compounds and in an equimolar mixture of 5 selected pesticides. The pesticides were previously analyzed for effects on the function of estrogen and androgen receptors, the aromatase enzyme and steroidogenesis in vitro. In this study, the effect on thyroid hormone (TH) function and aryl hydrocarbon receptor (AhR) transactivity was assessed using GH3 cell proliferation assay (T-screen) and AhR responsive luciferase reporter gene bioassay, respectively. Thirteen pesticides were analyzed as follows: 2-methyl-4-chlorophenoxyacetic acid, terbuthylazine, iodosulfuron-methyl-sodium, mesosulfuron-methyl, metsulfuron-methyl, chlormequat chloride, bitertanol, propiconazole, prothioconazole, mancozeb and its metabolite ethylene thiourea, cypermethrin, tau-fluvalinate, and malathion (currently banned in DK). In the T-screen, prothioconazole, malathion, tau-fluvalinate, cypermethrin, terbuthylazine and mancozeb significantly stimulated and bitertanol and propiconazole slightly reduced the GH3 cell proliferation. In the presence of triiodothyronine (T3), prothioconazole, tau-fluvalinate, propiconazole, cypermethrin and bitertanol significantly antagonized the T3-induced GH3 cell proliferation. Eleven of the tested pesticides agonized the AhR function, and bitertanol and prothioconazole inhibited the basal AhR activity. Bitertanol, propiconazole, prothioconazole and cypermethrin antagonized the TCDD-induced AhR transactivation at the highest tested concentration. The 5-component mixture had inducing effect but the combined effect could not be predicted due to the presence of bitertanol eliciting inhibitory effect. Upon removal of bitertanol from the mixture, the remaining four pesticides acted additively. In conclusion, our data suggest that pesticides currently used in Denmark

  3. Free and Open Source Chemistry Software in Research of Quantitative Structure-Toxicity Relationship of Pesticides

    Directory of Open Access Journals (Sweden)

    Rastija Vesna

    2017-01-01

    Full Text Available Pesticides are toxic chemicals aimed for the destroying pest on crops. Numerous data evidence about toxicity of pesticides on aquatic organisms. Since pesticides with similar properties tend to have similar biological activities, toxicity may be predicted from structure. Their structure feature and properties are encoded my means of molecular descriptors. Molecular descriptors can capture quite simple two-dimensional (2D chemical structures to highly complex three-dimensional (3D chemical structures. Quantitative structure-toxicity relationship (QSTR method uses linear regression analyses for correlation toxicity of chemical with their structural feature using molecular descriptors. Molecular descriptors were calculated using open source software PaDEL and in-house built PyMOL plugin (PyDescriptor. PyDescriptor is a new script implemented with the commonly used visualization software PyMOL for calculation of a large and diverse set of easily interpretable molecular descriptors encoding pharmacophoric patterns and atomic fragments. PyDescriptor has several advantages like free and open source, can work on all major platforms (Windows, Linux, MacOS. QSTR method allows prediction of toxicity of pesticides without experimental assay. In the present work, QSTR analysis for toxicity of a dataset of mixtures of 5 classes of pesticides comprising has been performed.

  4. Effects of chemical and biological pesticides on plant growth parameters and rhizospheric bacterial community structure in Vigna radiata

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Sunil; Gupta, Rashi; Sharma, Shilpi, E-mail: shilpi@dbeb.iitd.ac.in

    2015-06-30

    Highlights: • Non-target effects of pesticides employing qualitative and quantitative approaches. • Qualitative shifts in resident and active bacterial community structure. • Abundance of 16S rRNA gene and transcripts were reduced significantly. • Effects of biological pesticide similar to chemical pesticides on rhizospheric bacteria. - Abstract: With increasing application of pesticides in agriculture, their non-target effects on soil microbial communities are critical to soil health maintenance. The present study aimed to evaluate the effects of chemical pesticides (chlorpyrifos and cypermethrin) and a biological pesticide (azadirachtin) on growth parameters and the rhizospheric bacterial community of Vigna radiata. Qualitative and quantitative analysis by PCR-denaturing gradient gel electrophoresis (DGGE) and q-PCR, respectively, of the 16S rRNA gene and transcript were performed to study the impact of these pesticides on the resident and active rhizospheric bacterial community. While plant parameters were not affected significantly by the pesticides, a shift in the bacterial community structure was observed with an adverse effect on the abundance of 16S rRNA gene and transcripts. Chlorpyrifos showed almost complete degradation toward the end of the experiment. These non-target impacts on soil ecosystems and the fact that the effects of the biopesticide mimic those of chemical pesticides raise serious concerns regarding their application in agriculture.

  5. Effects of chemical and biological pesticides on plant growth parameters and rhizospheric bacterial community structure in Vigna radiata

    International Nuclear Information System (INIS)

    Singh, Sunil; Gupta, Rashi; Sharma, Shilpi

    2015-01-01

    Highlights: • Non-target effects of pesticides employing qualitative and quantitative approaches. • Qualitative shifts in resident and active bacterial community structure. • Abundance of 16S rRNA gene and transcripts were reduced significantly. • Effects of biological pesticide similar to chemical pesticides on rhizospheric bacteria. - Abstract: With increasing application of pesticides in agriculture, their non-target effects on soil microbial communities are critical to soil health maintenance. The present study aimed to evaluate the effects of chemical pesticides (chlorpyrifos and cypermethrin) and a biological pesticide (azadirachtin) on growth parameters and the rhizospheric bacterial community of Vigna radiata. Qualitative and quantitative analysis by PCR-denaturing gradient gel electrophoresis (DGGE) and q-PCR, respectively, of the 16S rRNA gene and transcript were performed to study the impact of these pesticides on the resident and active rhizospheric bacterial community. While plant parameters were not affected significantly by the pesticides, a shift in the bacterial community structure was observed with an adverse effect on the abundance of 16S rRNA gene and transcripts. Chlorpyrifos showed almost complete degradation toward the end of the experiment. These non-target impacts on soil ecosystems and the fact that the effects of the biopesticide mimic those of chemical pesticides raise serious concerns regarding their application in agriculture

  6. Pesticidal and pest repellency activities of a plant derived triterpenoid 2α,3β,21β,23,28-penta hydroxyl 12-oleanene against Tribolium castaneum

    Directory of Open Access Journals (Sweden)

    Alam Khan

    2014-01-01

    Full Text Available BACKGROUND: Tribolium castaneum (Herbst is a major pest of stored grain-based products, and cause severe damage to cereal grains throughout the world. The present investigation was aimed to determine the pesticidal and pest repellent activities of 2α,3β,21β,23,28-penta hydroxyl 12-oleanene against T. castaneum. The compound 2α,3β,21β,23,28-penta hydroxyl 12-oleanene is a triterpenoid which was isolated from the roots of Laportea crenulata Gaud. Surface film technique was used for pesticidal screening, whereas, pest repellency property of the triterpenoid was determined by filter paper disc method. RESULTS: At 24 hours of exposure duration, significant mortality records (80% and 86% were observed at doses 0.88 and 1.77 mg/cm². No significant change in mortality records was observed when duration of exposure was increased up to 48 hours. The triterpenoid showed significant repellency activity at doses 0.47 and 0.94 mg/cm². CONCLUSION: These data suggest that the triterpenoid 2α,3β,21β,23,28-penta hydroxyl 12-oleanene possess both pesticidal and pest repellency activities against T. castaneum and can be used in controlling the pest of grain-based products.

  7. Pesticide uptake in potatoes: model and field experiments.

    Science.gov (United States)

    Juraske, Ronnie; Vivas, Carmen S Mosquera; Velásquez, Alexander Erazo; Santos, Glenda García; Moreno, Mónica B Berdugo; Gomez, Jaime Diaz; Binder, Claudia R; Hellweg, Stefanie; Dallos, Jairo A Guerrero

    2011-01-15

    A dynamic model for uptake of pesticides in potatoes is presented and evaluated with measurements performed within a field trial in the region of Boyacá, Colombia. The model takes into account the time between pesticide applications and harvest, the time between harvest and consumption, the amount of spray deposition on soil surface, mobility and degradation of pesticide in soil, diffusive uptake and persistence due to crop growth and metabolism in plant material, and loss due to food processing. Food processing steps included were cleaning, washing, storing, and cooking. Pesticide concentrations were measured periodically in soil and potato samples from the beginning of tuber formation until harvest. The model was able to predict the magnitude and temporal profile of the experimentally derived pesticide concentrations well, with all measurements falling within the 90% confidence interval. The fraction of chlorpyrifos applied on the field during plant cultivation that eventually is ingested by the consumer is on average 10(-4)-10(-7), depending on the time between pesticide application and ingestion and the processing step considered.

  8. Health Risk Assessment of Pesticide Residues via Dietary Intake of Market Vegetables from Dhaka, Bangladesh

    Directory of Open Access Journals (Sweden)

    Md. Shakhaoat Hossain

    2013-02-01

    Full Text Available The present study was designed to assess the health risk of pesticide residues via dietary intake of vegetables collected from four top agro-based markets of Dhaka, Bangladesh. High performance liquid chromatography with a photo diode array detector (HPLC-PDA was used to determine six organophosphorus (chlorpyrifos, fenitrothion, parathion, ethion, acephate, fenthion, two carbamate (carbaryl and carbofuran and one pyrethroid (cypermethrin pesticide residues in twelve samples of three common vegetables (tomato, lady’s finger and brinjal. Pesticide residues ranged from below detectable limit (<0.01 to 0.36 mg/kg. Acephate, chlorpyrifos, ethion, carbaryl and cypermethrin were detected in only one sample, while co-occurrence occurred twice for fenitrothion and parathion. Apart from chlorpyrifos in tomato and cypermethrin in brinjal, all pesticide residues exceeded the maximum residue limit (MRL. Hazard risk index (HRI for ethion (10.12 and carbaryl (1.09 was found in lady’s finger and tomato, respectively. Rest of the pesticide residues were classified as not a health risk. A continuous monitoring and strict regulation should be enforced regarding control of pesticide residues in vegetables and other food commodities.

  9. N-body simulations for f(R) gravity using a self-adaptive particle-mesh code

    Science.gov (United States)

    Zhao, Gong-Bo; Li, Baojiu; Koyama, Kazuya

    2011-02-01

    We perform high-resolution N-body simulations for f(R) gravity based on a self-adaptive particle-mesh code MLAPM. The chameleon mechanism that recovers general relativity on small scales is fully taken into account by self-consistently solving the nonlinear equation for the scalar field. We independently confirm the previous simulation results, including the matter power spectrum, halo mass function, and density profiles, obtained by Oyaizu [Phys. Rev. DPRVDAQ1550-7998 78, 123524 (2008)10.1103/PhysRevD.78.123524] and Schmidt [Phys. Rev. DPRVDAQ1550-7998 79, 083518 (2009)10.1103/PhysRevD.79.083518], and extend the resolution up to k˜20h/Mpc for the measurement of the matter power spectrum. Based on our simulation results, we discuss how the chameleon mechanism affects the clustering of dark matter and halos on full nonlinear scales.

  10. 78 FR 18504 - Emamectin Benzoate; Pesticide Tolerance

    Science.gov (United States)

    2013-03-27

    ... availability and use of monitoring data and food preparation-reduction factors for washing, cooking, etc. may... Federal Food, Drug, and Cosmetic Act (FFDCA). DATES: This regulation is effective March 27, 2013... affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer...

  11. 75 FR 22240 - Cyprodinil; Pesticide Tolerances

    Science.gov (United States)

    2010-04-28

    ... commodities. In addition, a high performance liquid chromatography with mass spectrometry (HPLC/MS) method... Executive Order Reviews This final rule establishes tolerances under section 408(d) of FFDCA in response to... types of actions from review under Executive Order 12866, entitled Regulatory Planning and Review (58 FR...

  12. Pesticides in Brazilian freshwaters: a critical review.

    Science.gov (United States)

    Albuquerque, A F; Ribeiro, J S; Kummrow, F; Nogueira, A J A; Montagner, C C; Umbuzeiro, G A

    2016-07-13

    The widespread use of pesticides in agriculture can lead to water contamination and cause adverse effects on non-target organisms. Brazil has been the world's top pesticide market consumer since 2008, with 381 approved pesticides for crop use. This study provides a comprehensive literature review on the occurrence of pesticide residues in Brazilian freshwaters. We searched for information in official agency records and peer-reviewed scientific literature. Risk quotients were calculated to assess the potential risk posed to aquatic life by the individual pesticides based on their levels of water contamination. Studies about the occurrence of pesticides in freshwaters in Brazil are scarce and concentrated in few sampling sites in 5 of the 27 states. Herbicides (21) accounted for the majority of the substances investigated, followed by fungicides (11), insecticides (10) and plant growth regulators (1). Insecticides are the class of major concern. Brazil would benefit from the implementation of a nationwide pesticide freshwater monitoring program to support preventive, remediation and enforcement actions.

  13. Selective Production of 9R-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid from α-Linolenic Acid in Perilla Seed Oil Hydrolyzate by a Lipoxygenase from Nostoc Sp. SAG 25.82.

    Science.gov (United States)

    Kim, Kyoung-Rok; An, Jung-Ung; Lee, Seon-Hwa; Oh, Deok-Kun

    2015-01-01

    Hydroxy fatty acids (HFAs) derived from omega-3 polyunsaturated fatty acids have been known as versatile bioactive molecules. However, its practical production from omega-3 or omega-3 rich oil has not been well established. In the present study, the stereo-selective enzymatic production of 9R-hydroxy-10E,12Z,15Z-octadecatrienoic acid (9R-HOTE) from α-linolenic acid (ALA) in perilla seed oil (PO) hydrolyzate was achieved using purified recombinant 9R-lipoxygenase (9R-LOX) from Nostoc sp. SAG 25.82. The specific activity of the enzyme followed the order linoleic acid (LA) > ALA > γ-linolenic acid (GLA). A total of 75% fatty acids (ALA and LA) were used as a substrate for 9R-LOX from commercial PO by hydrolysis of Candida rugosa lipase. The optimal reaction conditions for the production of 9R-HOTE from ALA using 9R-LOX were pH 8.5, 15°C, 5% (v/v) acetone, 0.2% (w/v) Tween 80, 40 g/L ALA, and 1 g/L enzyme. Under these conditions, 9R-LOX produced 37.6 g/L 9R-HOTE from 40 g/L ALA for 1 h, with a conversion yield of 94% and a productivity of 37.6 g/L/h; and the enzyme produced 34 g/L 9R-HOTE from 40 g/L ALA in PO hydrolyzate for 1 h, with a conversion yields of 85% and a productivity of 34 g/L/h. The enzyme also converted 9R-hydroxy-10E,12Z-octadecadienoic acid (9R-HODE) from 40 g/L LA for 1.0 h, with a conversion yield of 95% and a productivity of 38.4 g/L. This is the highest productivity of HFA from both ALA and ALA-rich vegetable oil using LOX ever reported. Therefore, our result suggests an efficient method for the production of 9R-HFAs from LA and ALA in vegetable oil using recombinant LOX in biotechnology.

  14. Indication of pesticide effects and recolonization in streams.

    Science.gov (United States)

    Knillmann, Saskia; Orlinskiy, Polina; Kaske, Oliver; Foit, Kaarina; Liess, Matthias

    2018-07-15

    The agricultural use of pesticides leads to environmentally relevant pesticide concentrations that cause adverse effects on stream ecosystems. These effects on invertebrate community composition can be identified by the bio-indicator SPEAR pesticides . However, refuge areas have been found to partly confound the indicator. On the basis of three monitoring campaigns of 41 sites in Central Germany, we identified 11 refuge taxa. The refuge taxa, mainly characterized by dispersal-based resilience, were observed only nearby uncontaminated stream sections and independent of the level of pesticide pressure. Through incorporation of this information into the revised SPEAR pesticides indicator, the community structure specifically identified the toxic pressure and no longer depended on the presence of refuge areas. With regard to ecosystem functions, leaf litter degradation was predicted by the revised SPEAR pesticides and the median water temperature at a site (R 2  = 0.38, P = 0.003). Furthermore, we designed the bio-indicator SPEAR refuge to quantify the magnitude of general recolonization at a given stream site. We conclude that the taxonomic composition of aquatic invertebrate communities enables a specific indication of anthropogenic stressors and resilience of ecosystems. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Evaluation of pesticide residues in fruits and vegetables from Algeria.

    Science.gov (United States)

    Mebdoua, Samira; Lazali, Mohamed; Ounane, Sidi Mohamed; Tellah, Sihem; Nabi, Fahima; Ounane, Ghania

    2017-06-01

    A total of 160 samples of 13 types of fresh fruits and vegetables from domestic production and import were analysed to detect the presence of pesticide residues. Analysis was performed by multi-residual extraction followed by gas chromatography-mass spectrometry. In 42.5% of the tested samples, no residues were found and 12.5% of samples contained pesticide residues above maximum residue limits. Risk assessment for long-term exposure was done for all pesticides detected in this study. Except chlorpyrifos and lambda-cyhalothrin, exposure to pesticides from vegetables and fruits was below 1% of the acceptable daily intake. Short-term exposure assessment revealed that in seven pesticide/commodity combinations, including three pesticides (chlorpyrifos, deltamethrin and lambda-cyhalothrin), the acute reference dose had been exceeded.

  16. Molecular tagging of a novel rust resistance gene R(12) in sunflower (Helianthus annuus L.).

    Science.gov (United States)

    Gong, L; Hulke, B S; Gulya, T J; Markell, S G; Qi, L L

    2013-01-01

    Sunflower production in North America has recently suffered economic losses in yield and seed quality from sunflower rust (Puccinia helianthi Schwein.) because of the increasing incidence and lack of resistance to new rust races. RHA 464, a newly released sunflower male fertility restorer line, is resistant to both of the most predominant and most virulent rust races identified in the Northern Great Plains of the USA. The gene conditioning rust resistance in RHA 464 originated from wild Helianthus annuus L., but has not been molecularly marked or determined to be independent from other rust loci. The objectives of this study are to identify molecular markers linked to the rust resistance gene and to investigate the allelism of this gene with the unmapped rust resistance genes present in HA-R6, HA-R8 and RHA 397. Virulence phenotypes of seedlings for the F(2) population and F(2:3) families suggested that a single dominant gene confers rust resistance in RHA 464, and this gene was designated as R(12). Bulked segregant analysis identified ten markers polymorphic between resistant and susceptible bulks. In subsequent genetic mapping, the ten markers covered 33.4 cM of genetic distance on linkage group 11 of sunflower. A co-dominant marker CRT275-11 is the closest marker distal to R(12) with a genetic distance of 1.0 cM, while ZVG53, a dominant marker linked in the repulsion phase, is proximal to R(12) with a genetic distance of 9.6 cM. The allelism test demonstrated that R(12) is not allelic to the rust resistance genes in HA-R6, HA-R8 and RHA 397, and it is also not linked to any previously mapped rust resistance genes. Discovery of the R(12) novel rust resistance locus in sunflower and associated markers will potentially support the molecular marker-assisted introgression and pyramiding of R(12) into sunflower breeding lines.

  17. In vitro - in vivo correlations for endocrine activity of a mixture of currently used pesticides

    DEFF Research Database (Denmark)

    Taxvig, Camilla; Hadrup, Niels; Boberg, Julie

    2013-01-01

    Two pesticide mixtures were investigated for potential endocrine activity. Mix 3 consisted of bitertanol, propiconazole, and cypermethrin, and Mix 5 included malathion and terbuthylazine in addition to the three pesticides in Mix 3.All five single pesticides and the two mixtures were investigated...... for their ability to affect steroidogenesis in vitro in H295R cells. The pesticides alone and both mixtures affected steroidogenesis with both mixtures causing increase in progesterone and decrease in testosterone. For Mix 5 an increase in estradiol was seen as well, indicating increased aromatase activity.The two......, the hormonal responses in vitro were only partly reflected in vivo, probably due to some toxicokinetic issues, as the pesticide levels in the amniotic fluid also were found to be negatively affected by the number of compounds present in the mixtures. Nonetheless, the H295R assay gives hints on conceivable...

  18. Biosensor technology for pesticides--a review.

    Science.gov (United States)

    Verma, Neelam; Bhardwaj, Atul

    2015-03-01

    biochips technology. Also, the major technological advancements of nanotechnology in the field of biosensor technology are discussed. Various biosensors mentioned in manuscript are found to exhibit storage stability of biocomponent ranging from 30-60 days, detection limit of 10(-6) - 10(-16) M, response time of 1-20 min and applications of developed biosensors in environmental samples (water, food, vegetables, milk, and juice samples, etc.) are also discussed. Researchers all over the globe are working towards the development of different biosensing techniques based on contrast approaches for the detection of pesticides in various environmental samples.

  19. The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

    LENUS (Irish Health Repository)

    d'Adhemar, Charles J

    2014-01-01

    The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence that MyD88 positive cancer cells are clinically significant, stem-like and reproducibly detectable for the purposes of prognostic stratification. Expression of TLR4 and MyD88 was assessed immunohistochemically in 198 paraffin-embedded ovarian tissues and in an embryonal carcinoma model of cancer stemness. In parallel, expression of TLR4 and MyD88 mRNA and regulatory microRNAs (miR-21 and miR-146a) was assessed, as well as in a series of chemosensitive and resistant cancer cells lines. Functional analysis of the pathway was assessed in chemoresistant SKOV-3 ovarian cancer cells. TLR4 and MyD88 expression can be reproducibly assessed via immunohistochemistry using a semi-quantitative scoring system. TLR4 expression was present in all ovarian epithelium (normal and neoplastic), whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. MiR-21 and miR-146a expression was significantly increased in MyD88 negative cancers (p<0.05), indicating their participation in regulation. Significant alterations in MyD88 mRNA expression were observed between chemosensitive and chemoresistant cells and tissue. Knockdown of TLR4 in SKOV-3 ovarian cells recovered chemosensitivity. Knockdown of MyD88 alone did not. MyD88 expression was down-regulated in differentiated embryonal carcinoma (NTera2) cells, supporting the MyD88+ cancer stem cell hypothesis. Our findings demonstrate that expression of MyD88 is associated with significantly reduced patient survival and altered microRNA levels and suggest an intact\\/functioning TLR4\\/MyD88

  20. The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

    Directory of Open Access Journals (Sweden)

    Charles J d'Adhemar

    Full Text Available The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4, and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence that MyD88 positive cancer cells are clinically significant, stem-like and reproducibly detectable for the purposes of prognostic stratification. Expression of TLR4 and MyD88 was assessed immunohistochemically in 198 paraffin-embedded ovarian tissues and in an embryonal carcinoma model of cancer stemness. In parallel, expression of TLR4 and MyD88 mRNA and regulatory microRNAs (miR-21 and miR-146a was assessed, as well as in a series of chemosensitive and resistant cancer cells lines. Functional analysis of the pathway was assessed in chemoresistant SKOV-3 ovarian cancer cells. TLR4 and MyD88 expression can be reproducibly assessed via immunohistochemistry using a semi-quantitative scoring system. TLR4 expression was present in all ovarian epithelium (normal and neoplastic, whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. MiR-21 and miR-146a expression was significantly increased in MyD88 negative cancers (p<0.05, indicating their participation in regulation. Significant alterations in MyD88 mRNA expression were observed between chemosensitive and chemoresistant cells and tissue. Knockdown of TLR4 in SKOV-3 ovarian cells recovered chemosensitivity. Knockdown of MyD88 alone did not. MyD88 expression was down-regulated in differentiated embryonal carcinoma (NTera2 cells, supporting the MyD88+ cancer stem cell hypothesis. Our findings demonstrate that expression of MyD88 is associated with significantly reduced patient survival and altered microRNA levels and suggest an intact/functioning TLR4

  1. 75 FR 51048 - Notice of Receipt of Request to Voluntarily Cancel a Pesticide Registration

    Science.gov (United States)

    2010-08-18

    ... Voluntarily Cancel a Pesticide Registration AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... cancel a pesticide registration. DATES: Comments must be received on or before September 17, 2010... the registrant to cancel a technical grade active ingredient pesticide product registered under...

  2. Multiresidue method for the determination of pesticides in Oolong tea using QuEChERS by gas chromatography-triple quadrupole tandem mass spectrometry.

    Science.gov (United States)

    Wu, Chia-Chang

    2017-08-15

    We propose a simple, rapid analytical method for determination of 89 pesticides in Oolong tea by GC/MS/MS. Samples were extracted via QuEChERS. The limits of detection and quantification range of the 89 pesticides were 1-25μgL -1 and 10-50μgL -1 , respectively. Good separation was attained in less than 36min. A wide linear range of 1-250μgL -1 was observed with r 2 values from 0.9955 to 0.9998. Pesticide-free tea powder spiked at 50 and 100μgL -1 . Recovery ranges of the 86 (50μgL -1 ) and 83 (100μgL -1 ) pesticides were from 60% to 120%. Relative standard deviations were less than 20%. The laboratory proficiency test (FAPAS, 2014) shows satisfactory (|z|pesticides in Oolong tea. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Pesticide residues in grain from Kazakhstan and potential health risks associated with exposure to detected pesticides.

    Science.gov (United States)

    Lozowicka, B; Kaczynski, P; Paritova, Capital A Cyrillic Е; Kuzembekova, G B; Abzhalieva, A B; Sarsembayeva, N B; Alihan, K

    2014-02-01

    This paper presents the first study of pesticide residue results in grain from Kazakhstan. A total of 80 samples: barley, oat, rye, and wheat were collected and tested in the accredited laboratory. Among 180 pesticides, 10 active substances were detected. Banned pesticides, such as DDTs, γ-HCH, aldrin and diazinon were found in cereal grain. Chlorpyrifos methyl and pirimiphos methyl were the most frequently detected residues. No residues were found in 77.5% of the samples, 13.75% contained pesticide residues at or below MRLs, and 8.75% above MRLs. The greatest percentage of samples with residues (29%) was noted for wheat, and the lowest for rye (20%). Obtained data were used to estimate potential health risks associated with exposure to these pesticides. The highest estimated daily intakes (EDIs) were as follows: 789% of the ADI for aldrin (wheat) and 49.8% of the ADI for pirimiphos methyl (wheat and rye). The acute risk from aldrin and tebuconazole in wheat was 315.9% and 98.7% ARfD, respectively. The results show that despite the highest EDIs of pesticide residues in cereals, the current situation could not be considered a serious public health problem. Nevertheless, an investigation into continuous monitoring of pesticide residues in grain is recommended. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Rapid Determination of Thiabendazole Pesticides in Rape by Surface Enhanced Raman Spectroscopy

    Directory of Open Access Journals (Sweden)

    Lei Lin

    2018-04-01

    Full Text Available Thiabendazole is widely used in sclerotium blight, downy mildew and black rot prevention and treatment in rape. Accurate monitoring of thiabendazole pesticides in plants will prevent potential adverse effects to the Environment and human health. Surface Enhanced Raman Spectroscopy (SERS is a highly sensitive fingerprint with the advantages of simple operation, convenient portability and high detection efficiency. In this paper, a rapid determination method of thiabendazole pesticides in rape was conducted combining SERS with chemometric methods. The original SERS were pretreated and the partial least squares (PLS was applied to establish the prediction model between SERS and thiabendazole pesticides in rape. As a result, the SERS enhancing effect based on silver Nano-substrate was better than that of gold Nano-substrate, where the detection limit of thiabendazole pesticides in rape could reach 0.1 mg/L. Moreover, 782, 1007 and 1576 cm−1 could be determined as thiabendazole pesticides Raman characteristic peaks in rape. The prediction effect of thiabendazole pesticides in rape was the best ( R p 2 = 0.94, RMSEP = 3.17 mg/L after the original spectra preprocessed with 1st-Derivative, and the linear relevance between thiabendazole pesticides concentration and Raman peak intensity at 782 cm−1 was the highest (R2 = 0.91. Furthermore, five rape samples with unknown thiabendazole pesticides concentration were used to verify the accuracy and reliability of this method. It was showed that prediction relative standard deviation was 0.70–9.85%, recovery rate was 94.71–118.92% and t value was −1.489. In conclusion, the thiabendazole pesticides in rape could be rapidly and accurately detected by SERS, which was beneficial to provide a rapid, accurate and reliable scheme for the detection of pesticides residues in agriculture products.

  5. 77 FR 69838 - MON 87410 and MON 87411 Pesticide-Incorporated Protectant Corn Events: Pesticide Experimental Use...

    Science.gov (United States)

    2012-11-21

    ... FURTHER INFORMATION CONTACT: Shanaz Bacchus, Biopesticides and Pollution Prevention Division (7511P..., Keith Matthews, Director, Biopesticides and Pollution Prevention Division, Office of Pesticide Programs...

  6. H12CN and H13CN excitation analysis in the circumstellar outflow of R Sculptoris

    Science.gov (United States)

    Saberi, M.; Maercker, M.; De Beck, E.; Vlemmings, W. H. T.; Olofsson, H.; Danilovich, T.

    2017-03-01

    Context. The 12CO/13CO isotopologue ratio in the circumstellar envelope (CSE) of asymptotic giant branch (AGB) stars has been extensively used as the tracer of the photospheric 12C/13C ratio. However, spatially-resolved ALMA observations of R Scl, a carbon rich AGB star, have shown that the 12CO/13CO ratio is not consistent over the entire CSE. Hence, it can not necessarily be used as a tracer of the 12C/13C ratio. The most likely hypothesis to explain the observed discrepancy between the 12CO/13CO and 12C/13C ratios is CO isotopologue selective photodissociation by UV radiation. Unlike the CO isotopologue ratio, the HCN isotopologue ratio is not affected by UV radiation. Therefore, HCN isotopologue ratios can be used as the tracer of the atomic C ratio in UV irradiated regions. Aims: We aim to present ALMA observations of H13CN(4-3) and APEX observations of H12CN(2-1), H13CN(2-1, 3-2) towards R Scl. These new data, combined with previously published observations, are used to determine abundances, ratio, and the sizes of line-emitting regions of the aforementioned HCN isotopologues. Methods: We have performed a detailed non-LTE excitation analysis of circumstellar H12CN(J = 1-0, 2-1, 3-2, 4-3) and H13CN(J = 2-1, 3-2, 4-3) line emission around R Scl using a radiative transfer code based on the accelerated lambda iteration (ALI) method. The spatial extent of the molecular distribution for both isotopologues is constrained based on the spatially resolved H13CN(4-3) ALMA observations. Results: We find fractional abundances of H12CN/H2 = (5.0 ± 2.0) × 10-5 and H13CN/H2 = (1.9 ± 0.4) × 10-6 in the inner wind (r ≤ (2.0 ± 0.25) ×1015 cm) of R Scl. The derived circumstellar isotopologue ratio of H12CN/H13CN = 26.3 ± 11.9 is consistent with the photospheric ratio of 12C/13C 19 ± 6. Conclusions: We show that the circumstellar H12CN/H13CN ratio traces the photospheric 12C/13C ratio. Hence, contrary to the 12CO/13CO ratio, the H12CN/H13CN ratio is not affected by UV

  7. Cosmology based on f(R) gravity admits 1 eV sterile neutrinos.

    Science.gov (United States)

    Motohashi, Hayato; Starobinsky, Alexei A; Yokoyama, Jun'ichi

    2013-03-22

    It is shown that the tension between recent neutrino oscillation experiments, favoring sterile neutrinos with masses of the order of 1 eV, and cosmological data which impose stringent constraints on neutrino masses from the free streaming suppression of density fluctuations, can be resolved in models of the present accelerated expansion of the Universe based on f(R) gravity.

  8. Removal of six pesticide residues in cowpea with alkaline electrolysed water.

    Science.gov (United States)

    Han, Yongtao; Song, Le; An, Quanshun; Pan, Canping

    2017-06-01

    Reduction of six pesticide residues (isoprocarb, chlorpyrifos, bifenthrin, beta-cypermethrin, difenoconazole and azoxystrobin) in cowpea by alkaline electrolysed water (AlEW) solutions with different pH was investigated. The commonly used washing treatments in household processing were used for comparison. The residue magnitudes were determined by gas chromatography coupled with tandem mass spectrometry (GC-MS/MS). Results showed that the removal effect of AlEW solution on the six pesticides was superior to tap water, 5% sodium chloride, 5% sodium carbonate and 5% acetic acid solution. AlEW with pH 12.2 had more potential to eliminate the six pesticides in cowpeas. Moreover, the reduction of pesticide residues gradually increased with the increase of washing time. This study demonstrated that AlEW solution with pH of 12.2 could be used to reduce pesticide residues on fresh cowpea samples. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  9. Sulindac inhibits pancreatic carcinogenesis in LSL-KrasG12D-LSL-Trp53R172H-Pdx-1-Cre mice via suppressing aldo-keto reductase family 1B10 (AKR1B10).

    Science.gov (United States)

    Li, Haonan; Yang, Allison L; Chung, Yeon Tae; Zhang, Wanying; Liao, Jie; Yang, Guang-Yu

    2013-09-01

    Sulindac has been identified as a competitive inhibitor of aldo-keto reductase 1B10 (AKR1B10), an enzyme that plays a key role in carcinogenesis. AKR1B10 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and exhibits lipid substrate specificity, especially for farnesyl and geranylgeranyl. There have been no studies though showing that the inhibition of PDAC by sulindac is via inhibition of AKR1B10, particularly the metabolism of farnesyl/geranylgeranyl and Kras protein prenylation. To determine the chemopreventive effects of sulindac on pancreatic carcinogenesis, 5-week-old LSL-Kras(G12D)-LSL-Trp53(R172H)-Pdx-1-Cre mice (Pan(kras/p53) mice) were fed an AIN93M diet with or without 200 p.p.m. sulindac (n = 20/group). Kaplan-Meier survival analysis showed that average animal survival in Pan(kras/p53) mice was 143.7 ± 8.8 days, and average survival with sulindac was increased to 168.0 ± 8.8 days (P < 0.005). Histopathological analyses revealed that 90% of mice developed PDAC, 10% with metastasis to the liver and lymph nodes. With sulindac, the incidence of PDAC was reduced to 56% (P < 0.01) and only one mouse had lymph node metastasis. Immunochemical analysis showed that sulindac significantly decreased Ki-67-labeled cell proliferation and markedly reduced the expression of phosphorylated extracellular signal-regulated kinases 1 and 2 (ERK1/2), c-Raf and mitogen-activated protein kinase kinase 1 and 2. In in vitro experiments with PDAC cells from Pan(kras/p53) mice, sulindac exhibited dose-dependent inhibition of AKR1B10 activity. By silencing AKR1B10 expression through small interfering RNA or by sulindac treatment, these in vitro models showed a reduction in Kras and human DNA-J homolog 2 protein prenylation, and downregulation of phosphorylated C-raf, ERK1/2 and MEK1/2 expression. Our results demonstrate that sulindac inhibits pancreatic carcinogenesis by the inhibition of Kras protein prenylation by targeting AKR1B10.

  10. My Dream, My World

    Institute of Scientific and Technical Information of China (English)

    Joseph DeVeto; 赵惠妙

    2005-01-01

    @@ I often dream the same dream: I am driving together with my mother on a stretched straight path1.The birds are singing and playing2 around the car, the flowers are opening3 richly4 which decorate5 the land.The breeze is flirting with ourhair, my long, black waterfall and my mother's short gray hair6.

  11. Environmental Chemistry Methods (ECM) Index - R

    Science.gov (United States)

    Laboratories use testing methods to identify pesticides in water and soil. Environmental chemistry methods test soil and water samples to determine the fate of pesticides in the environment. Find methods for chemicals with R as the first character.

  12. Long-Term Persistence of Pesticides and TPs in Archived Agricultural Soil Samples and Comparison with Pesticide Application.

    Science.gov (United States)

    Chiaia-Hernandez, Aurea C; Keller, Armin; Wächter, Daniel; Steinlin, Christine; Camenzuli, Louise; Hollender, Juliane; Krauss, Martin

    2017-09-19

    For polar and more degradable pesticides, not many data on long-term persistence in soil under field conditions and real application practices exist. To assess the persistence of pesticides in soil, a multiple-compound screening method (log K ow 1.7-5.5) was developed based on pressurized liquid extraction, QuEChERS and LC-HRMS. The method was applied to study 80 polar pesticides and >90 transformation products (TPs) in archived topsoil samples from the Swiss Soil Monitoring Network (NABO) from 1995 to 2008 with known pesticide application patterns. The results reveal large variations between crop type and field sites. For the majority of the sites 10-15 pesticides were identified with a detection rate of 45% at concentrations between 1 and 330 μg/kg dw in soil. Furthermore, TPs were detected in 47% of the cases where the "parent-compound" was applied. Overall, residues of about 80% of all applied pesticides could be detected with half of these found as TPs with a persistence of more than a decade.

  13. Evaluación por rendimiento de 12 genotipos promisorios de fríjol voluble (Phaseolus vulgaris L. tipo Bola roja y Reventón para las zonas frías de Colombia

    Directory of Open Access Journals (Sweden)

    López Jesús Edgardo

    2006-12-01

    Full Text Available

    10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville;">El fríjol común (10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville-Italic; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville-Italic;">Phaseolus vulgaris 10.0pt; font-family: ";Cambria";,";serif";; mso-ascii-theme-font: major-latin; mso-fareast-font-family: Baskerville; mso-hansi-theme-font: major-latin; mso-bidi-font-family: Baskerville;">L. es un alimento básico en la región Andina por ser una fuente rica en proteína y de bajo costo. La investigación para incrementar rendimientos en esta leguminosa es una opción para mejorar la competitividad en el mercado mundial. El objetivo principal de este trabajo fue evaluar por rendimiento los genotipos promisorios de fríjol voluble, tipos Bola roja y Reventón, para las zonas frías de Colombia mediante el análisis de sendero. Se realizó un diseño de bloques completos al azar con tres réplicas para evaluar 10 genotipos promisorios de fríjol voluble. El análisis de sendero para el rendimiento por planta y las correlaciones entre el rendimiento y sus componentes mostraron que el carácter número de vainas por planta es el de mayor importancia sobre la determinación del rendimiento, en comparación con los caracteres peso de 100 semillas y número de semillas por vaina, tanto en los genotipos de fríjol voluble tipo Bola roja como tipo Reventón. 

  14. In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.

    Science.gov (United States)

    Takeuchi, Shinji; Iida, Mitsuru; Yabushita, Hisatoshi; Matsuda, Tadashi; Kojima, Hiroyuki

    2008-12-01

    The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that regulates genes involved in xenobiotic metabolism, cellular proliferation and differentiation. In this study, we have developed a highly sensitive AhR-mediated reporter cell line, DR-EcoScreen cells, which are mouse hepatoma Hepa1c1c7 cells stably transfected with a reporter plasmid containing seven copies of dioxin-responsive element. Using these DR-EcoScreen cells, we performed the reporter gene assay and characterized the AhR agonistic activities of 200 pesticides (29 organochlorines, 11 diphenyl ethers, 56 organophosphorus pesticides, 12 pyrethroids, 22 carbamates, 12 acid amides, 7 triazines, 6 ureas, and 45 others). Eleven of the 200 pesticides (acifluorfen-methyl, bifenox, chlorpyrifos, isoxathion, quinalphos, chlorpropham, diethofencarb, propanil, diuron, linuron, and prochloraz) showed AhR-mediated transcriptional activity. In particular, three herbicides (propanil, diuron, and linuron) have a common chemical structure and showed more potent agonistic activity than other pesticides. To investigate the in vivo effects, we examined the gene expression of AhR-inducible cytochrome P450 1As (CYP1As) in the liver of female C57BL/6 mice intraperitoneally injected with these three herbicides (300 mg kg(-1)) by quantitative RT-PCR, resulting in induction of significant high levels of CYP1A1 and CYP1A2 mRNAs. This indicates that propanil, diuron and linuron possess AhR-mediated transactivation effect in vivo as well as in vitro. Through the present study, we demonstrated that DR-EcoScreen cells are useful for sensitive, rapid and simple identification of AhR agonists among a large number of environmental chemicals.

  15. 78 FR 36774 - Agency Information Collection Activities; Proposed Collection; Comment Request; Pesticide...

    Science.gov (United States)

    2013-06-19

    ... Activities; Proposed Collection; Comment Request; Pesticide Registration Fees Program AGENCY: Environmental... collection activity or ICR does this action apply to? Title: Pesticide Registration Fees Program. ICR number... under Sections 3 and 24(c) of the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA). In...

  16. MyGeoHub: A Collaborative Geospatial Research and Education Platform

    Science.gov (United States)

    Kalyanam, R.; Zhao, L.; Biehl, L. L.; Song, C. X.; Merwade, V.; Villoria, N.

    2017-12-01

    Scientific research is increasingly collaborative and globally distributed; research groups now rely on web-based scientific tools and data management systems to simplify their day-to-day collaborative workflows. However, such tools often lack seamless interfaces, requiring researchers to contend with manual data transfers, annotation and sharing. MyGeoHub is a web platform that supports out-of-the-box, seamless workflows involving data ingestion, metadata extraction, analysis, sharing and publication. MyGeoHub is built on the HUBzero cyberinfrastructure platform and adds general-purpose software building blocks (GABBs), for geospatial data management, visualization and analysis. A data management building block iData, processes geospatial files, extracting metadata for keyword and map-based search while enabling quick previews. iData is pervasive, allowing access through a web interface, scientific tools on MyGeoHub or even mobile field devices via a data service API. GABBs includes a Python map library as well as map widgets that in a few lines of code, generate complete geospatial visualization web interfaces for scientific tools. GABBs also includes powerful tools that can be used with no programming effort. The GeoBuilder tool provides an intuitive wizard for importing multi-variable, geo-located time series data (typical of sensor readings, GPS trackers) to build visualizations supporting data filtering and plotting. MyGeoHub has been used in tutorials at scientific conferences and educational activities for K-12 students. MyGeoHub is also constantly evolving; the recent addition of Jupyter and R Shiny notebook environments enable reproducible, richly interactive geospatial analyses and applications ranging from simple pre-processing to published tools. MyGeoHub is not a monolithic geospatial science gateway, instead it supports diverse needs ranging from just a feature-rich data management system, to complex scientific tools and workflows.

  17. Calibration of the Chemcatcher passive sampler for monitoring selected polar and semi-polar pesticides in surface water

    International Nuclear Information System (INIS)

    Gunold, Roman; Schaefer, Ralf Bernhard; Paschke, Albrecht; Schueuermann, Gerrit; Liess, Matthias

    2008-01-01

    Passive sampling is a powerful method for continuous pollution monitoring, but calibration experiments are still needed to generate sampling rates in order to estimate water concentrations for polar compounds. We calibrated the Chemcatcher device with an uncovered SDB-XC Empore disk as receiving phase for 12 polar and semi-polar pesticides in aquatic environments in flow-through tank experiments at two water flow velocities (0.135 m/s and 0.4 m/s). In the 14-day period of exposure the uptake of test substances in the sampler remained linear, and all derived sampling rates R s were in the range of 0.1 to 0.5 L/day. By additionally monitoring the release of two preloaded polar pesticides from the SDB-XC disks over time, very high variation in release kinetics was found, which calls into question the applicability of performance reference compounds. Our study expands the applicability of the Chemcatcher for monitoring trace concentrations of pesticides with frequent occurrence in water. - We calibrated the Chemcatcher passive sampler for current-use polar pesticides in surface waters, allowing its application in future monitoring studies

  18. Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder.

    Science.gov (United States)

    Schmidt, Rebecca J; Kogan, Vladimir; Shelton, Janie F; Delwiche, Lora; Hansen, Robin L; Ozonoff, Sally; Ma, Claudia C; McCanlies, Erin C; Bennett, Deborah H; Hertz-Picciotto, Irva; Tancredi, Daniel J; Volk, Heather E

    2017-09-08

    Maternal folic acid (FA) protects against developmental toxicity from certain environmental chemicals. We examined combined exposures to maternal FA and pesticides in relation to autism spectrum disorder (ASD). Participants were California children born from 2000-2007 who were enrolled in the Childhood Autism Risks from Genetics and the Environment (CHARGE) case-control study at age 2-5 y, were clinically confirmed to have ASD (n=296) or typical development (n=220), and had information on maternal supplemental FA and pesticide exposures. Maternal supplemental FA and household pesticide product use were retrospectively collected in telephone interviews from 2003-2011. High vs. low daily FA intake was dichotomized at 800μg (median). Mothers' addresses were linked to a statewide database of commercial applications to estimate agricultural pesticide exposure. High FA intake (≥800μg) during the first pregnancy month and no known pesticide exposure was the reference group for all analyses. Compared with this group, ASD was increased in association with pesticide exposure {adjusted odds ratio [OR]=2.5 [95% confidence interval (CI): 1.3, 4.7]} compared with low FA [OR=1.2 (95% CI: 0.7, 2.2)] or indoor pesticides [OR=1.7 (95% CI: 1.1, 2.8)] alone. ORs for the combination of low FA and regular pregnancy exposure (≥6 mo) to pet pesticides or to outdoor sprays and foggers were 3.9 (95% CI: 1.4, 11.5) and 4.1 (95% CI: 1.7, 10.1), respectively. ORs for low maternal FA and agricultural pesticide exposure 3 mo before or after conception were 2.2 (95% CI: 0.7, 6.5) for chlorpyrifos, 2.3 (95% CI: 0.98, 5.3) for organophosphates, 2.1 (95% CI: 0.9, 4.8) for pyrethroids, and 1.5 (95% CI: 0.5, 4.8) for carbamates. Except for carbamates, these ORs were approximately two times greater than those for either exposure alone or for the expected ORs for combined exposures under multiplicative or additive models. In this study population, associations between pesticide exposures and ASD

  19. Effect of organochlorine pesticides on human androgen receptor activation in vitro

    International Nuclear Information System (INIS)

    Lemaire, Geraldine; Terouanne, Beatrice; Mauvais, Pascale; Michel, Serge; Rahmani, Roger

    2004-01-01

    Many persistent organochlorine pesticides (OCs) have been implicated in adverse effects, that is, reproductive and developmental effects, in man and in wildlife alike. It has been hypothesized that these so-called xeno-hormones could be responsible for the increased incidence in various male sexual differentiation disorders such as hypospadias, cryptorchidism, low sperm counts and quality. In this report, OCs, called endocrine disrupters, were tested for their interaction with the androgen receptor. The stable prostatic cell line PALM, which contains a human androgen receptor (hAR) expression vector and the reporter MMTV-luciferase, was used to characterize the response of hAR to OC and was compared with synthetic androgen compound R1881. We found that all the OC pesticides tested were able to shift the agonist [ 3 H]-R1881 from its binding site to the AR in competitive binding assays. In addition, these compounds antagonize - in a dose-dependent manner - the AR-mediated transcription by synthetic AR ligand R1881. None of the pesticides reacted as agonists. These results demonstrate that OC endocrine activities in vivo probably result from direct and specific binding to the AR ligand-binding domain. Although the antagonistic potential of OC pesticides is lower than that of hydroxyflutamide, they are capable of disrupting the male hormone signaling pathway. Because these chemicals are extremely persistent and tend to bioaccumulate, these results support the hypothesis that the recent increase in the incidence of male sexual disorders could be due to long exposure to ubiquitous OC pesticides found in the environment

  20. Thin layer chromatographic analyses of pesticides in a soil ecosystem

    International Nuclear Information System (INIS)

    Afful, S.; Dogbe, S.A.; Ahmad, K.; Ewusie, A.T.

    2008-01-01

    Silica gel 60, silica gel 60 F 254 , and aluminium oxide as adsorbents were used to investigate their suitability for the analysis and detection of the pesticides: nitrofen, atrazine, diuron, dioxacarb, propoxur, propanil, carbaryl and cypermethrin in soil ecosystem using ethyl acetate, chloroform, dichloromethane and ethyl acetate/chloroform (1:1) as developing solvents. O-tolidine and potassium iodide reagent were used for the detection of pesticides. R f values obtained for the pesticides using the silica gel 60-ethyl acetate. silica gel 60F 254 -ethyl acetate, silica gel 60 chloroform, silica gel 60 F 254 - chloroform, silica gel 60 - (1:1) ethyl acetate/chloroform and silica gel 60 F 254 - (1:1) ethyl acetate/chloroform systems generally were within the stipulated range of 0.4-0.8. R f values obtained for the pesticides using silica gel 60-dichloromethane systems were very low except for cypermethrin and nitrofen. Analysis with aluminium oxide coated plates gave a heavy yellow background with the detection reagent making visualization of spots difficult. Aluminium oxide coated plate is, therefore, not recommended when o-tolidine plus potassium iodide is used as detection reagent. (au)

  1. A general framework to test gravity using galaxy clusters - I. Modelling the dynamical mass of haloes in f(R) gravity

    Science.gov (United States)

    Mitchell, Myles A.; He, Jian-hua; Arnold, Christian; Li, Baojiu

    2018-06-01

    We propose a new framework for testing gravity using cluster observations, which aims to provide an unbiased constraint on modified gravity models from Sunyaev-Zel'dovich (SZ) and X-ray cluster counts and the cluster gas fraction, among other possible observables. Focusing on a popular f(R) model of gravity, we propose a novel procedure to recalibrate mass scaling relations from Λ cold dark matter (ΛCDM) to f(R) gravity for SZ and X-ray cluster observables. We find that the complicated modified gravity effects can be simply modelled as a dependence on a combination of the background scalar field and redshift, fR(z)/(1 + z), regardless of the f(R) model parameter. By employing a large suite of N-body simulations, we demonstrate that a theoretically derived tanh fitting formula is in excellent agreement with the dynamical mass enhancement of dark matter haloes for a large range of background field parameters and redshifts. Our framework is sufficiently flexible to allow for tests of other models and inclusion of further observables, and the one-parameter description of the dynamical mass enhancement can have important implications on the theoretical modelling of observables and on practical tests of gravity.

  2. 75 FR 56897 - S-metolachlor; Pesticide Tolerances

    Science.gov (United States)

    2010-09-17

    ... not limited to those engaged in the following activities: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide manufacturing (NAICS code 32532... 13-07B at 0.15 ppm; onion, bulb, subgroup 3-07A at 0.1 ppm; and onion, green, subgroup 3-07B at 2.0...

  3. Exposure to pesticides with dermal toxicity in farmers of Community of Valencia Exposición a plaguicidas con toxicidad dérmica en agricultores de la Comunitat Valenciana

    Directory of Open Access Journals (Sweden)

    Caterina Brandon Garcia

    2010-12-01

    Full Text Available Introduction: Dermal route has a toxicological importance, as well as substances such as entry, but by frequent local effects. In applications of pesticides by farmers is common and important the dermal exposure to pesticides, so the dermal route in this sector of activity could be of particular relevance. Objective: To determine the hazard of dermal exposure in farmers using pesticides and to propose specific preventive measures. Material and methods: A transversal descriptive study based on a questionnaire designed by the researchers, replying to the 238 attendees at the courses for pesticide handler card basic level Department of Health Xativa-Ontinyent (Valencia in 2009. Pesticides used were collected over the past 12 months and reviewed their R phrases (risk phrases looking for dermal effects. Results: 55 % of pesticides had some phrase R on skin problems. The phrase R38 "Irritating to skin" was found in 16 products, used by 59.05 % of respondents and the R43 "Possibility of sensitization by skin contact" at 7, used by 23.91 %. Conclusions: The skin irritation effect was related to more dermal exposure to these pesticides. It is necessary to emphasize the skin protection in the courses for workers who apply these products. Skin problems should be included damages for workplace exposure to pesticides.Introducción: La vía dérmica tiene importancia toxicológica, además de como entrada de sustancias, por los frecuentes efectos locales. En aplicaciones de plaguicidas realizadas por agricultores resulta habitual e importante la exposición dérmica a plaguicidas, por lo que la vía dérmica en este sector de actividad puede resultar de especial relevancia. Objetivo: Conocer los riesgos cutáneos de los agricultores que utilizan plaguicidas, para poder así proponer medidas preventivas específicas. Material y métodos: Se realizó un estudio descriptivo transversal basado en un cuestionario diseñado por los investigadores, contestando al

  4. 77 FR 59188 - Registration Review; Pesticide Dockets Opened for Review and Comment

    Science.gov (United States)

    2012-09-26

    ... (case 5110). These pesticides do not currently have any actively registered pesticide products and are... justice. EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement of any... their location, cultural practices, or other factors, may have atypical or disproportionately high and...

  5. Fatty Acid Methyl Ester (FAME) Succession in Different Substrates as Affected by the Co-Application of Three Pesticides.

    Science.gov (United States)

    Cardinali, Alessandra; Pizzeghello, Diego; Zanin, Giuseppe

    2015-01-01

    In intensive agriculture areas the use of pesticides can alter soil properties and microbial community structure with the risk of reducing soil quality. In this study the fatty acid methyl esters (FAMEs) evolution has been studied in a factorial lab experiment combining five substrates (a soil, two aged composts and their mixtures) treated with a co-application of three pesticides (azoxystrobin, chlorotoluron and epoxiconazole), with two extraction methods, and two incubation times (0 and 58 days). FAMEs extraction followed the microbial identification system (MIDI) and ester-linked method (EL). The pesticides showed high persistence, as revealed by half-life (t1/2) values ranging from 168 to 298 days, which confirms their recalcitrance to degradation. However, t1/2 values were affected by substrate and compost age down to 8 days for chlorotoluron in S and up to 453 days for epoxiconazole in 12M. Fifty-six FAMEs were detected. Analysis of variance (ANOVA) showed that the EL method detected a higher number of FAMEs and unique FAMEs than the MIDI one, whereas principal component analysis (PCA) highlighted that the monosaturated 18:1ω9c and cyclopropane 19:0ω10c/19ω6 were the most significant FAMEs grouping by extraction method. The cyclopropyl to monoenoic acids ratio evidenced higher stress conditions when pesticides were applied to compost and compost+soil than solely soil, as well as with final time. Overall, FAMEs profiles showed the importance of the extraction method for both substrate and incubation time, the t1/2 values highlighted the effectiveness of solely soil and the less mature compost in reducing the persistence of pesticides.

  6. Fatty Acid Methyl Ester (FAME Succession in Different Substrates as Affected by the Co-Application of Three Pesticides.

    Directory of Open Access Journals (Sweden)

    Alessandra Cardinali

    Full Text Available In intensive agriculture areas the use of pesticides can alter soil properties and microbial community structure with the risk of reducing soil quality.In this study the fatty acid methyl esters (FAMEs evolution has been studied in a factorial lab experiment combining five substrates (a soil, two aged composts and their mixtures treated with a co-application of three pesticides (azoxystrobin, chlorotoluron and epoxiconazole, with two extraction methods, and two incubation times (0 and 58 days. FAMEs extraction followed the microbial identification system (MIDI and ester-linked method (EL.The pesticides showed high persistence, as revealed by half-life (t1/2 values ranging from 168 to 298 days, which confirms their recalcitrance to degradation. However, t1/2 values were affected by substrate and compost age down to 8 days for chlorotoluron in S and up to 453 days for epoxiconazole in 12M. Fifty-six FAMEs were detected. Analysis of variance (ANOVA showed that the EL method detected a higher number of FAMEs and unique FAMEs than the MIDI one, whereas principal component analysis (PCA highlighted that the monosaturated 18:1ω9c and cyclopropane 19:0ω10c/19ω6 were the most significant FAMEs grouping by extraction method. The cyclopropyl to monoenoic acids ratio evidenced higher stress conditions when pesticides were applied to compost and compost+soil than solely soil, as well as with final time.Overall, FAMEs profiles showed the importance of the extraction method for both substrate and incubation time, the t1/2 values highlighted the effectiveness of solely soil and the less mature compost in reducing the persistence of pesticides.

  7. 77 FR 72984 - Buprofezin Pesticide Tolerances; Technical Correction

    Science.gov (United States)

    2012-12-07

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 180 [EPA-HQ-OPP-2011-0759; FRL-9371-3] Buprofezin..., 2012, concerning buprofezin pesticide tolerances. This document corrects a typographical error. DATES...: Sec. 180.511 Buprofezin; tolerances for residues. (a) * * * Parts per Commodity million...

  8. Emergence of running dark energy from polynomial f(R) theory in Palatini formalism

    Energy Technology Data Exchange (ETDEWEB)

    Szydlowski, Marek [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Jagiellonian University, Mark Kac Complex Systems Research Centre, Krakow (Poland); Stachowski, Aleksander [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Borowiec, Andrzej [University of Wroclaw, Institute of Theoretical Physics, Wroclaw (Poland)

    2017-09-15

    We consider FRW cosmology in f(R)= R + γR{sup 2} + δR{sup 3} modified framework. The Palatini approach reduces its dynamics to the simple generalization of Friedmann equation. Thus we study the dynamics in two-dimensional phase space with some details. After reformulation of the model in the Einstein frame, it reduces to the FRW cosmological model with a homogeneous scalar field and vanishing kinetic energy term. This potential determines the running cosmological constant term as a function of the Ricci scalar. As a result we obtain the emergent dark energy parametrization from the covariant theory. We study also singularities of the model and demonstrate that in the Einstein frame some undesirable singularities disappear. (orig.)

  9. Alexandru Popa, Untersuchungen zu den römisch-barbarischen Kontakten Östlich der römischen Provinz Dacia Antiquitatis reihe 3 Abhnadlungen zur vor-und frühgeschichte, zur klassichen und provinzial-römischen archäologie und zur geschichte des altertum

    Directory of Open Access Journals (Sweden)

    Vasile Iarmulschi

    2016-06-01

    Full Text Available Review on book - Alexandru Popa, Untersuchungen zu den römisch-barbarischen Kontakten Östlich der römischen Provinz Dacia Antiquitatis reihe 3 Abhnadlungen zur vor-und frühgeschichte, zur klassichen und provinzial-römischen archäologie und zur geschichte des altertum

  10. CASE STUDY: Ecuador — Preventing pesticide poisonings in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-01-10

    Jan 10, 2011 ... At the same time, pesticides that were purchased in powder form had to be mixed ... So the researchers faced "some real push backs by agro-chemical ... how pesticide residues can travel between people and through homes, ...

  11. Life cycle human health impacts of 875 pesticides

    DEFF Research Database (Denmark)

    Fantke, Peter; Jolliet, Oliver

    2016-01-01

    present a consistent framework for characterizing human toxicological impacts associated with pesticides applied to agricultural crops in the frame of life cycle impact assessment based on state-of-the-art data and methods. Methods We combine a dynamic multicrop plant uptake model designed for evaluating......-crop combinations of 10 orders of magnitude. Conclusions Our framework is operational for use in current life cycle impact assessment models, is made available for USEtox, and closes an important gap in the assessment of human exposure to pesticides. For ready use in life cycle assessment studies, we present...... pesticide-crop combination-specific characterization factors normalized to pesticide mass applied and provide default data for application times and loss due to post-harvest food processing. When using our data, we emphasize the need to consult current pesticide regulation, since each pesticide...

  12. 10 CFR 470.12 - Management.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Management. 470.12 Section 470.12 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION APPROPRIATE TECHNOLOGY SMALL GRANTS PROGRAM § 470.12 Management. (a) The... Management and Budget Circular A-106 entitled “Standard Federal Regulations” are met. Regional Program...

  13. 78 FR 1570 - Semiannual Regulatory Agenda

    Science.gov (United States)

    2013-01-08

    ... Deregulatory Priorities. Gregory H. Woods, General Counsel. Energy Efficiency and Renewable Energy--Proposed... Action 10/01/12 77 FR 59719 Regulatory Flexibility Analysis Required: Yes. Agency Contact: Stephen Witkowski, Phone: 202 586-7463, Email: stephen[email protected] . RIN: 1904-AB90 [FR Doc. 2012-31497...

  14. Spherical thin shells in F(R) gravity. Construction and stability

    Energy Technology Data Exchange (ETDEWEB)

    Eiroa, Ernesto F. [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina); Universidad de Buenos Aires, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Figueroa Aguirre, Griselda [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina)

    2018-01-15

    We present a broad class of spherical thin shells of matter in F(R) gravity. We show that the corresponding junction conditions determine the equation of state between the energy density and the pressure/tension at the surface. We analyze the stability of the static configurations under perturbations preserving the symmetry. We apply the formalism to the construction of charged bubbles and we find that there exist stable static configurations for a suitable set of the parameters of the model. (orig.)

  15. Spherical thin shells in F(R) gravity. Construction and stability

    International Nuclear Information System (INIS)

    Eiroa, Ernesto F.; Figueroa Aguirre, Griselda

    2018-01-01

    We present a broad class of spherical thin shells of matter in F(R) gravity. We show that the corresponding junction conditions determine the equation of state between the energy density and the pressure/tension at the surface. We analyze the stability of the static configurations under perturbations preserving the symmetry. We apply the formalism to the construction of charged bubbles and we find that there exist stable static configurations for a suitable set of the parameters of the model. (orig.)

  16. Acute Pesticide Poisoning in Children: Hospital Review in Selected Hospitals of Tanzania

    Directory of Open Access Journals (Sweden)

    Elikana Lekei

    2017-01-01

    Full Text Available Background. Acute pesticide poisoning (APP is a serious problem worldwide. Because the burden of childhood APP is unknown in Tanzania, this study describes the distribution, circumstances, and patterns of APP involving children under 18 years in Tanzania. Methodology. A 12-month prospective study was conducted in 10 Tanzanian healthcare facilities in 2006 using a data collection tool for surveillance. Results. Of 53 childhood poisoning cases identified, 56.6% were female. The most common poisoning circumstances were accidents (49.1% and suicide (30.2%. The most vulnerable children were 16-17 years old (30.2%. Suicide was significantly more common in females (PRR females/males = 1.66; 95% CI = 1.03–2.68 and accidental cases were more common in children aged 10 years or younger. Suicide was concentrated in children over 10 years, comprising 53% of cases in this age group. Organophosphates (OPs, zinc phosphide, and endosulfan were common amongst reported poisoning agents. The annual APP incidence rate was 1.61/100,000. Conclusion. APP is common among children in this region of Tanzania. Prevention of suicide in older children should address mental health issues and control access to toxic pesticides. Prevention of accidents in younger children requires safer storage and hygiene measures. Diverse interventions are needed to reduce pesticide poisoning among children in Tanzania.

  17. 40 CFR 158.2120 - Microbial pesticides product analysis data requirements table.

    Science.gov (United States)

    2010-07-01

    ... Certification of limits R MP EP -- Physical and Chemical Characteristics 830.6302 Color R TGAI TGAI -- 830.6303....6319 Miscibility R MP EP 2 830.6320 Corrosion Characteristics R MP EP 3 830.7000 pH R TGAI TGAI -- 830... pesticides are packaged in metal, plastic, or paper containers. 4. Only required for liquid forms of...

  18. Interaction of organophosphorus pesticides with DNA nucleotides on a Boron-doped diamond electrode

    Energy Technology Data Exchange (ETDEWEB)

    Garbellini, Gustavo S.; Uliana, Carolina V.; Yamanaka, Hideko, E-mail: gustgarb@yahoo.com.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Bauru, SP (Brazil). Dept. de Quimica Analitica

    2013-12-01

    Diamond electrode was used to evaluate the interaction of the nucleotides guanosine monophosphate (GMP) and adenosine monophosphate (AMP) with the pesticides chlorpyrifos, methamidophos and monocrotophos. Changes were observed in the currents and peak potentials of the nucleotide voltammograms in the presence of the pesticides, with dependence on the pesticide concentration (from 5.0 Multiplication-Sign 10{sup -7} to 5.0 Multiplication-Sign 10{sup -5} mol L{sup -1}) and the interaction time (from 1 min to 4 h). This is probably due to binding of the pesticides to the nitrogenous bases present in the nucleotides, which could lead to problems in the DNA replication and biological functions of nucleotides. The pesticides showed stronger interaction with AMP than with GMP. Studies of the interaction of 50 Micro-Sign g mL{sup -1} DNA with the pesticides (from 30 min to 4 h and from 1.0 Multiplication-Sign 10{sup -6} to 6.0 Multiplication-Sign 10{sup -5} mol L{sup -1}) did not reveal any peaks relating to double helix opening or DNA unwinding. (author)

  19. [Reactivity of several classes of pesticides with UV, ozone and permanganate].

    Science.gov (United States)

    Liu, Chao; Qiang, Zhi-min; Tian, Fang; Zhang, Tao

    2009-01-01

    The reactivity of eight classes of 26 extensively used pesticides, namely, organochlorines, thiadiazole, dinitroanaline, acetamides, triazines, uracil and carbamates, with three common disinfectants or oxidants including UV254 (average intensity of 10.8 mW x cm(-2)), ozone (dosage of 4.1 - 6.2 mg x L(-1)) and permanganate (dosage of 15.8 mg x L(-1)) was investigated. The reactions were allowed to proceed for 30 min at pH 7.0 and ambient temperature (25 degrees C +/- 3 degrees C). Results indicate that under the applied experimental conditions, more than 95% of chlorobenzilate, etridiazole, alachlor, butachlor, metolachlor, propachlor, atrazine, simazine, aldicarb, oxamyl and methiocarb could be effectively removed by UV254; and the removal efficiencies of other pesticides were in a range of 12.9%-77.7%. Ozone could completely degrade chloroneb, dichlorvos, bromacil, aldicarb, carbaryl, carbofuran, oxamyl and methiocarb; prometon and aldicarb sulfone were resistant to ozonation; and the removal efficiencies of other pesticides varied from 19.0% to 93.1%. Permanganate could fully degrade dichlorvos, aldicarb and methiocarb; organochlorines, dinitroanaline, thiadiazole, acetamides and other carbamates were resistant to permanganate oxidation; and the removal efficiencies of other pesticides ranged from 16.0% to 88.2%. If the practical dosage applied in drinking water treatment is considered, it is expected that most of the pesticides will be completely degraded by ozone, a few by permanganate, but probably none by UV254 .

  20. In Vivo Tes of Dicofol on Cocoon Production and Viability of Earthworm Pontoscolex corethrurus Fr. Mull

    Science.gov (United States)

    Sumarmin, R.; Huda, N. K.; Yuniarti, E.

    2018-04-01

    The uncontrol using of pesticides, harmful to the environment, health, and it would have impact to non-target animal as earthworm. This study describes the effect of the Dicofol to cocoon production and viability of earthworm Pontoscolex corethrurus Fr. Mull., has been done in-July - Augustus 2016 at the zoology laboratory of Biology Department of Universitas Negeri Padang. The experiment used the Completely Randomized Design (4 treatments 6 replications). The treatments are with 0 g / l (P1), 0.002 g / L (P2), 0.004 g / L (P3), and 0.006 g / L (P4) and 0.008 g / L of Dicofol that diluted to water. The Data of production and viability of earthworm cocoons Pontoscolex corethrurus Fr. Mull collected during 30 days in alternate day. Data analyzed by ANOVA and Duncan New Multiple Range Test at p <0.05. The results Showed that the average number of cocoons production at P1 30 cocoons (the highest), 16 cocoons P2, P3 7 cocoons, and the P4 and P5 0 cocoons (the Lowest). The average percentage of cocoons viability were highest in P1, and P2 (100%); P3 (10%) and the cancel at P4 and P5 (0%). It can conclude that the pesticide Dicofol decreased the production and viability of the earthworm cocoons Pontoscolex corethrurus Fr. Mull.

  1. Persistent Pesticides in Human Breast Milk and Cryptorchidism

    Science.gov (United States)

    Damgaard, Ida N.; Skakkebæk, Niels E.; Toppari, Jorma; Virtanen, Helena E.; Shen, Heqing; Schramm, Karl-Werner; Petersen, Jørgen H.; Jensen, Tina K.; Main, Katharina M.

    2006-01-01

    Introduction Prenatal exposure to some pesticides can adversely affect male reproductive health in animals. We investigated a possible human association between maternal exposure to 27 organochlorine compounds used as pesticides and cryptorchidism among male children. Design Within a prospective birth cohort, we performed a case–control study; 62 milk samples from mothers of cryptorchid boys and 68 from mothers of healthy boys were selected. Milk was collected as individual pools between 1 and 3 months postpartum and analyzed for 27 organochlorine pesticides. Results Eight organochlorine pesticides were measurable in all samples (medians; nanograms per gram lipid) for cases/controls: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (p,p′-DDE): 97.3/83.8; β-hexachlorocyclohexane (β-HCH): 13.6/12.3; hexachlorobenzene (HCB): 10.6/8.8; α -endosulfan: 7.0/6.7; oxychlordane: 4.5/4.1; 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (p,p′-DDT): 4.6/4.0; dieldrin: 4.1/3.1; cis-heptachloroepoxide (cis-HE): 2.5/2.2. Five compounds [octachlorostyrene (OCS); pentachlorobenzene, 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (p,p′-DDD); o,p′-DDT; mirex] were measurable in most samples (detection rates 90.8–99.2%) but in lower concentrations. For methoxychlor, cis-chlordane, pentachloroanisole (PCA), γ -HCH, 1,1-dichloro-2-(2-chlorophenyl)-2,2(4-chlorophenyl)ethane, trans-chlordane, α -HCH, and o,p′-DDE, both concentrations and detection rates were low (26.5–71.5%). Heptachlor, HCH (δ, ɛ ), aldrin, β-endosulfan and trans-heptachloroepoxide were detected at negligible concentrations and low detection rates and were not analyzed further. Seventeen of 21 organochlorine pesticides [p,p′-DDT, p,p′-DDE, p,p′-DDD, o,p′-DDT, HCH (α , β, γ ), HCB, PCA, α -endosulfan, cis-HE, chlordane (cis-, trans-) oxychlordane, methoxychlor, OCS, and dieldrin] were measured in higher median concentrations in case milk than in control milk. Apart from trans-chlordane (p = 0

  2. Pliocene geomagnetic polarity epochs

    Science.gov (United States)

    Dalrymple, G.B.; Cox, A.; Doell, Richard R.; Gromme, C.S.

    1967-01-01

    A paleomagnetic and K-Ar dating study of 44 upper Miocene and Pliocene volcanic units from the western United States suggests that the frequency of reversals of the earth's magnetic field during Pliocene time may have been comparable with that of the last 3.6 m.y. Although the data are too limited to permit the formal naming of any new polarity epochs or events, four polarity transitions have been identified: the W10 R/N boundary at 3.7 ?? 0.1 m.y., the A12 N/R boundary at 4.9 ?? 0.1 m.y., the W32 N/R boundary at 9.0 ?? 0.2m.y., and the W36 R/N boundary at 10.8 ?? 0.3 - 1.0 m.y. The loss of absolute resolution of K-Ar dating in older rocks indicates that the use of well defined stratigraphic successions to identify and date polarity transitions will be important in the study of Pliocene and older reversals. ?? 1967.

  3. 10 CFR 12.305 - Settlement.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Settlement. 12.305 Section 12.305 Energy NUCLEAR... Considering Applications § 12.305 Settlement. The applicant and the NRC counsel may agree on a proposed settlement of the award before final action on the application, either in connection with a settlement of the...

  4. 10 CFR 218.12 - Pricing.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Pricing. 218.12 Section 218.12 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.12 Pricing. The price for oil subject to a supply order issued pursuant to this subpart shall be based on the price conditions...

  5. Antimicrobial Pesticides

    Science.gov (United States)

    EPA regulates pesticides under the statutory authority of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The registration requirements for antimicrobial pesticides differ somewhat from those of other pesticides. Find out more.

  6. 77 FR 59190 - Halofenozide; Notice of Receipt of Requests To Voluntarily Cancel Pesticide Registrations and...

    Science.gov (United States)

    2012-09-26

    ... of Requests To Voluntarily Cancel Pesticide Registrations and Terminate All Uses AGENCY... voluntarily cancel pesticide registrations of all products containing the pesticide halofenozide. The requests would cancel all technical and end-use registrations and delete all halofenozide uses. The requests...

  7. Cosmology based on f(R) gravity with O(1) eV sterile neutrino

    Energy Technology Data Exchange (ETDEWEB)

    Chudaykin, Anton S.; Gorbunov, Dmitry S. [Institute for Nuclear Research of the Russian Academy of Sciences, 60th October Anniversary prospect 7a, Moscow 117312 (Russian Federation); Starobinsky, Alexei A. [L.D. Landau Institute for Theoretical Physics of the Russian Academy of Sciences, Moscow 119334 (Russian Federation); Burenin, Rodion A., E-mail: chudy@ms2.inr.ac.ru, E-mail: gorby@ms2.inr.ac.ru, E-mail: alstar@landau.ac.ru, E-mail: rodion@hea.iki.rssi.ru [Space Research Institute of the Russian Academy of Sciences (IKI), Moscow, ul. Profsoyuznaya, 84/32, 117997 (Russian Federation)

    2015-05-01

    We address the cosmological role of an additional O(1) eV sterile neutrino in modified gravity models. We confront the present cosmological data with predictions of the FLRW cosmological model based on a variant of f(R) modified gravity proposed by one of the authors previously. This viable cosmological model which deviation from general relativity with a cosmological constant Λ decreases as R{sup −2n} for large, but not too large values of the Ricci scalar R (while no Λ is introduced by hand at small R) provides an alternative explanation of present dark energy and the accelerated expansion of the Universe (the case n=2 is considered in the paper). Various up-to-date cosmological data sets exploited include measurements of the cosmic microwave background (CMB) anisotropy, the CMB lensing potential, the baryon acoustic oscillations (BAO), the cluster mass function and the Hubble constant. We find that the CMB+BAO constraints strongly restrict the sum of neutrino masses from above. This excludes values of the model parameter λ∼ 1 for which distinctive cosmological features of the model are mostly pronounced as compared to the ΛCDM model, since then free streaming damping of perturbations due to neutrino rest masses is not sufficient to compensate their extra growth occurring in f(R) modified gravity. Thus, in the gravity sector we obtain λ>8.2 (2σ) with the account of systematic uncertainties in galaxy cluster mass function measurements and λ>9.4 (2σ) without them. At the same time in the latter case we find for the sterile neutrino mass 0.47 eV < m{sub ν, sterile} < 1 eV (2σ) assuming that the sterile neutrinos are thermalized and the active neutrinos are massless, not significantly larger than in the standard ΛCDM with the same data set: 0.45 eV < m{sub ν, sterile} < 0.92 eV (2σ). However, a possible discovery of a sterile neutrino with the mass m{sub ν, sterile} ≈ 1.5 eV motivated by various anomalies in neutrino oscillation

  8. Evaluating the Zebrafish Embryo Toxicity Test for Pesticide ...

    Science.gov (United States)

    Given the numerous chemicals used in society, it is critical to develop tools for accurate and efficient evaluation of potential risks to human and ecological receptors. Fish embryo acute toxicity tests are 1 tool that has been shown to be highly predictive of standard, more resource-intensive, juvenile fish acute toxicity tests. However, there is also evidence that fish embryos are less sensitive than juvenile fish for certain types of chemicals, including neurotoxicants. The utility of fish embryos for pesticide hazard assessment was investigated by comparing published zebrafish embryo toxicity data from pesticides with median lethal concentration 50% (LC50) data for juveniles of 3 commonly tested fish species: rainbow trout, bluegill sunfish, and sheepshead minnow. A poor, albeit significant, relationship (r2 = 0.28; p embryo and juvenile fish toxicity when pesticides were considered as a single group, but a much better relationship (r2 = 0.64; p embryo toxicity test endpoints are particularly insensitive to neurotoxicants. These results indicate that it is still premature to replace juvenile fish toxicity tests with embryo-based tests such as the Organisation for Economic Co-op

  9. Biotransformation of pesticides in saturated-zone materials

    Science.gov (United States)

    Hoyle, Blythe L.; Arthur, Ellen L.

    Many studies have been conducted to evaluate pesticide contamination of groundwater in the United States, but investigations of pesticide biotransformation in saturated zones are much less numerous than in surface soils. Because results of studies using soils are not directly applicable to the subsurface, the purpose of this paper is to illustrate examples of pesticide biotransformation in saturated-zone materials. Although it must be considered with caution, the US Environmental Protection Agency's (EPA) "Pesticides in Ground Water Database" was used to focus the discussion on the biotransformation potential of dibromoethane (EDB), atrazine, acetanilide herbicides, and aldicarb, all of which have been detected in groundwater in the United States. Results of more than two dozen studies indicate that a biotransformation potential for these pesticides exists in saturated-zone materials, although for any given pesticide substantial differences in biotransformation occurred. These variations were due both to differences in experimental methods and to heterogeneities in the subsurface materials under investigation. However, because biotransformation mechanisms were not well investigated, it is generally not possible to extrapolate predictions of biotransformation potential beyond the specific sites investigated. These results highlight the need to better understand microbial genetic regulation of biotransformation processes so that genetic information may be effectively incorporated into future investigations of biotransformation potential in the subsurface. Résumé De nombreuses études ont été réalisées pour évaluer le degré de pollution des aquifères par les pesticides aux États-Unis, mais les recherches concernant la biotransformation des pesticides dans les eaux souterraines sont beaucoup moins nombreuses que dans les sols. Du fait que les résultats des études concernant les sols ne sont pas directement applicables au milieu souterrain, le propos de cet

  10. The origin of high magnetic properties in (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, K., E-mail: koba@ms.sist.ac.jp [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Suzuki, S.; Kuno, T.; Urushibata, K. [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Sakuma, N.; Yano, M.; Shoji, T.; Kato, A. [Toyota Motor Corporation, 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan); Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan); Manabe, A. [Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan)

    2017-03-15

    Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn{sub 12}-type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe{sub 0.75}Co{sub 0.25}), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti{sub 1.0} to −Ti{sub 0.5}, which increased the Fe and Co content, preserved the ThMn{sub 12} structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe{sub 11}Ti{sub 1.0}N{sub 1.5}, and by 7% for the Co-containing, (Nd{sub 0.7}Zr{sub 0.3}) (Fe{sub 0.75}Co{sub 0.25}) {sub 11.5}Ti{sub 0.5}N{sub 1.3} alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

  11. Systematic study of photoluminescence upon band gap excitation in perovskite-type titanates R 1/2Na1/2TiO3:Pr (R=La, Gd, Lu, and Y)

    International Nuclear Information System (INIS)

    Inaguma, Yoshiyuki; Tsuchiya, Takeshi; Katsumata, Tetsuhiro

    2007-01-01

    Pr 3+ -doped perovskites R 1/2 Na 1/2 TiO 3 :Pr (R=La, Gd, Lu, and Y) were synthesized, and their structures, optical absorption and luminescent properties were investigated, and the relationship between structures and optical properties are discussed. Optical band gap of R 1/2 Na 1/2 TiO 3 increases in the order R=La, Gd, Y, and Lu, which is primarily due to a decrease in band width accompanied by a decrease in Ti-O-Ti bond angle. Intense red emission assigned to f-f transition of Pr 3+ from the excited 1 D 2 level to the ground 3 H 4 state upon the band gap photo-excitation (UV) was observed for all compounds. The wavelength of emission peaks was red-shifted in the order R=La, Gd, Y, and Lu, which originates from the increase in crystal field splitting of Pr 3+ . This is attributed to the decrease in inter-atomic distances of Pr-O together with the inter-atomic distances (R, Na)-O, i.e., increase in covalency between Pr and O. The results indicate that the luminescent properties in R 1/2 Na 1/2 TiO 3 :Pr are governed by the relative energy level between the ground and excited state of 4f 2 for Pr 3+ , and the conduction and valence band, which is primarily dependent on the structure, e.g., the tilt of TiO 6 octahedra and the Pr-Ti inter-atomic distance and the site symmetry of Pr ion. - Graphical abstract: The red intense emission assigned to f-f transition of Pr 3+ from the excited 1 D 2 level to the ground 3 H 4 state upon the band gap photo-excitation (UV) was observed upon the band gap photo-excitation in perovskites R 1/2 Na 1/2 TiO 3 :Pr(R=La, Gd, Lu, and Y). It was found that the systematic changes in their luminescent properties are strongly dependent on the structure

  12. Pesticide Labels

    Science.gov (United States)

    Pesticide labels translate results of our extensive evaluations of pesticide products into conditions, directions and precautions that define parameters for use of a pesticide with the goal of ensuring protection of human health and the environment.

  13. Digitala spel : En kvalitativ studie om E-sportspelares erfarenheter från karriär och upplevd hälsa

    OpenAIRE

    Szilagyi, Ivan

    2017-01-01

    Ungdomar och unga vuxna är de främsta användarna av digitala spel och även de främsta entusiasterna av fenomenet E-sport. Spelvanor är av betydelse då studier har påvisat att det finns determinanter, både fysiologiska och psykologiska som kan påverka individens välbefinnande.Syftet med studien var att undersöka professionella E-sportspelares erfarenheter av att utöva sin sport och hur de upplever att detta påverkar hälsan. En kvalitativ metod användes och datainsamling utfördes genom intervju...

  14. Explosion i rötkammare med biogas

    DEFF Research Database (Denmark)

    Hedlund, Frank Huess

    2017-01-01

    En biogasreaktor exploderade 1990 på Vejle Centrala reningsverk. Nu, 24 år senare, när biogas är populärare än någonsin, har händelsen helt försvunnit från tillgängliga, öppna källor......En biogasreaktor exploderade 1990 på Vejle Centrala reningsverk. Nu, 24 år senare, när biogas är populärare än någonsin, har händelsen helt försvunnit från tillgängliga, öppna källor...

  15. Q ‑ Φ criticality and microstructure of charged AdS black holes in f(R) gravity

    Science.gov (United States)

    Deng, Gao-Ming; Huang, Yong-Chang

    2017-12-01

    The phase transition and critical behaviors of charged AdS black holes in f(R) gravity with a conformally invariant Maxwell (CIM) source and constant curvature are further investigated. As a highlight, this research is carried out by employing new state parameters (T,Q, Φ) and contributes to deeper understanding of the thermodynamics and phase structure of black holes. Our analyses manifest that the charged f(R)-CIM AdS black hole undergoes a first-order small-large black hole phase transition, and the critical behaviors qualitatively behave like a Van der Waals liquid-vapor system. However, differing from the case in Einstein’s gravity, phase structures of the black holes in f(R) theory exhibit an interesting dependence on gravity modification parameters. Moreover, we adopt the thermodynamic geometry to probe the black hole microscopic properties. The results show that, on the one hand, both the Ruppeiner curvature and heat capacity diverge exactly at the critical point, on the other hand, the f(R)-CIM AdS black hole possesses the property as ideal Fermi gases. Of special interest, we discover a microscopic similarity between the black holes and a Van der Waals liquid-vapor system.

  16. Disentangling the f(R)-duality

    Energy Technology Data Exchange (ETDEWEB)

    Broy, Benedict J.; Westphal, Alexander [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 Germany (Germany); Pedro, Francisco G., E-mail: benedict.broy@desy.de, E-mail: francisco.pedro@desy.de, E-mail: alexander.westphal@desy.de [Departamento de Física Teórica and Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid, Cantoblanco, Madrid, 28049 Spain (Spain)

    2015-03-01

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R{sup n} with 1R{sup 2}-term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m{sup 2}φ{sup 2}-inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R{sup 2} model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-ℓ.

  17. Disentangling the f(R)-duality

    Energy Technology Data Exchange (ETDEWEB)

    Broy, Benedict J. [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 (Germany); Pedro, Francisco G. [Departamento de Física Teórica and Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid, Cantoblanco, Madrid, 28049 (Spain); Westphal, Alexander [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 (Germany)

    2015-03-16

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R{sup n} with 1R{sup 2}-term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m{sup 2}ϕ{sup 2}-inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R{sup 2} model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-ℓ.

  18. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents.

    Science.gov (United States)

    Hurley, P M

    1998-08-01

    Of 240 pesticides screened for carcinogenicity by the U.S. Environmental Protection Agency Office of Pesticide Programs, at least 24 (10%) produce thyroid follicular cell tumors in rodents. Thirteen of the thyroid carcinogens also induce liver tumors, mainly in mice, and 9 chemicals produce tumors at other sites. Some mutagenic data are available on all 24 pesticides producing thyroid tumors. Mutagenicity does not seem to be a major determinant in thyroid carcinogenicity, except for possibly acetochlor; evidence is less convincing for ethylene thiourea and etridiazole. Studies on thyroid-pituitary functioning, including indications of thyroid cell growth and/or changes in thyroxine, triiodothyronine, or thyroid-stimulating hormone levels, are available on 19 pesticides. No such antithyroid information is available for etridiazole, N-octyl bicycloheptene dicarboximide, terbutryn, triadimefon, and trifluralin. Of the studied chemicals, only bromacil lacks antithyroid activity under study conditions. Intrathyroidal and extrathyroidal sites of action are found: amitrole, ethylene thiourea, and mancozeb are thyroid peroxidase inhibitors; and acetochlor, clofentezine, fenbuconazole, fipronil, pendimethalin, pentachloronitrobenzene, prodiamine, pyrimethanil, and thiazopyr seem to enhance the hepatic metabolism and excretion of thyroid hormone. Thus, with 12 pesticides that mode of action judgments can be made, 11 disrupt thyroid-pituitary homeostasis only; no chemical is mutagenic only; and acetochlor may have both antithyroid and some mutagenic activity. More information is needed to identify other potential antithyroid modes of thyroid carcinogenic action.

  19. 7 CFR 29.3052 - Red color (R).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Red color (R). 29.3052 Section 29.3052 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Red color (R). A brownish red. [24 FR 8771, Oct. 29, 1959. Redesignated at 47 FR 51722, Nov. 17, 1982...

  20. Pesticides in persimmons, jujubes and soil from China: Residue levels, risk assessment and relationship between fruits and soils.

    Science.gov (United States)

    Liu, Yihua; Li, Shiliang; Ni, Zhanglin; Qu, Minghua; Zhong, Donglian; Ye, Caifen; Tang, Fubin

    2016-01-15

    Extreme and uncontrolled usage of pesticides produces a number of problems for vegetation and human health. In this study, the existence of organophosphates (OPs), organochlorines (OCs), pyrethroids (PYs) and fungicides (FUs) were investigated in persimmons/jujubes and their planted soils, which were collected from China. One OP (dimethoate), three OCs (DDT, quintozene and aldrin), six PYs (bifenthrin, fenpropathrin, cyhalothrin, cypermethrin, fenvalerate and deltamethrin) and two FUs (triadimefon and buprofezin) were found in 36.4% of persimmons and 70.8% of jujubes, with concentrations from 1.0 μg/kg to 2945.0 μg/kg. The most frequently detected pesticides in the two fruits were fenpropathrin in persimmons and cypermethrin in jujubes, with the detection frequencies of 30.0% and 22.7%, respectively. The residues of 4.5% (persimmon) and 25.0% (jujube) of samples were higher than the maximum residue limits (MRLs) of China. Compared with the fruits, more types of pesticides and higher residues were observed in their planted soils. The most frequently detected pesticides were HCH in persimmon soil and DDT in jujube soil, with the detection frequencies of 10.9% and 12.7%, respectively. For the tested samples, 39.1% of fruit samples and 63.0% of soil samples with multiple residues (containing more than two pesticides) were noted, even up to 8 residues in fruits and 14 residues in soils. Except for cyhalothrin, the other short-term risks for the tested pesticides in the fruits were below 10%, and the highest long-term risk was 14.13% for aldrin and dieldrin. There was no significant health risk for consumers via consumption of the two fruits. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Concentrations of organochlorine pesticides and 2,4,6-trichloroanisole in cork bark.

    Science.gov (United States)

    Olivella, M Àngels; Caixach, Josep; Planas, Carles; Oliveras, Anna; Jové, Patrícia

    2012-02-01

    Organochlorine pesticides are persistent lipophilic organic pollutants and tend to accumulate in growing plants. During growth, cork is in contact with the open air for long periods (9-12 years). Owing to the previous widespread use of organochlorine pesticides and their high persistence in the environment, there is a risk that residues of such pesticides may be present in cork. In this study, the concentrations of 14 organochlorine pesticides-all of which are indicators of environmental pollution-were analyzed in cork bark samples from three regions in Spain and one in Portugal. In addition, the concentrations of 2,4,6-trichlorophenol (TCP) and 2,4,6-trichloroanisole (TCA) were also analyzed. Our results show only very low concentrations of lindane, γ-HCH (cork sample from Extremadura (0.1 ng g(-1)) and p,p'-DDE was present at a maximum concentration of 2.9 ng g(-1) in a cork sample from Castile-La Mancha. However, all concentrations were well below the legal limit established by Regulation (EC) No. 396/2005 (10 ng g(-1) in foodstuffs). We can conclude, therefore, that the cork samples we studied complied with food safety standards. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Real-time PCR-based genotyping from whole blood using Taq DNA polymerase and a buffer supplemented with 1,2-propanediol and trehalose

    Czech Academy of Sciences Publication Activity Database

    Utekal, Pavol; Kocanda, Lukáš; Matoušek, P.; Wagner, P.; Bugajev, Viktor; Dráber, Petr

    2015-01-01

    Roč. 416, January (2015), s. 178-182 ISSN 0022-1759 R&D Projects: GA ČR(CZ) GBP302/12/G101; GA MPO FR-TI3/067; GA ČR(CZ) GA14-09807S; GA ČR(CZ) GA14-00703S Institutional support: RVO:68378050 Keywords : 1,2-Propanediol * real-time PCR * SYBR Green I * Taq DNA polymerase * trehalose * Unseparated blood Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.858, year: 2015

  3. 78 FR 38319 - Pesticide Maintenance Fee: Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide...

    Science.gov (United States)

    2013-06-26

    ... Technology and Resources Management Division (7502P), Office of Pesticide Programs, Environmental Protection... . FOR FURTHER INFORMATION CONTACT: Michael Yanchulis, Information Technology and Resources Management... Home Pest Insect Bifenthrin. Killer. 000264-00378 264 Larvin Brand DF Thiodicarb Thiodicarb...

  4. 77 FR 76979 - Pesticides; Revisions to Minimum Risk Exemption

    Science.gov (United States)

    2012-12-31

    ... industries such as animal feed (NAICS code 311119), cosmetics (NAICS code 325620), and soap and detergents... reporting of production to EPA. To meet the criteria for the minimum risk exemption, a pesticide must...

  5. Risques d'exposition aux résidus de pesticides via les produits ...

    African Journals Online (AJOL)

    NGOM

    peut également affecter les organismes non ciblés. Ainsi beaucoup d'insectes .... Pour les produits agricoles, une micro- extraction de ..... sont les principaux facteurs de la .... Contrôle des pesticides organochlors dans le lait et produits laitiers.

  6. 43 CFR 43.220 - By when must I publish my drug-free workplace statement and establish my drug-free awareness...

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false By when must I publish my drug-free workplace statement and establish my drug-free awareness program? 43.220 Section 43.220 Public Lands: Interior Office of the Secretary of the Interior GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients...

  7. f(R) global monopole revisited

    Energy Technology Data Exchange (ETDEWEB)

    Carames, Thiago R.P.; Fabris, Julio C.; Belich, H. [Universidade Federal do Espirito Santo (UFES), Vitoria, ES (Brazil); Bezerra de Mello, E.R. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil)

    2017-07-15

    In this paper the f(R) global monopole is reexamined. We provide an exact solution for the modified field equations in the presence of a global monopole for regions outside its core, generalizing previous results. Additionally, we discuss some particular cases obtained from this solution. We consider a setup consisting of a possible Schwarzschild black hole that absorbs the topological defect, giving rise to a static black hole endowed with a monopole's charge. Besides, we demonstrate how the asymptotic behavior of the Higgs field far from the monopole's core is shaped by a class of spacetime metrics which includes the ones analyzed here. In order to assess the gravitational properties of this system, we analyze the geodesic motion of both massive and massless test particles moving in the vicinity of such configuration. For the material particles we set the requirements they have to obey in order to experience stable orbits. On the other hand, for the photons we investigate how their trajectories are affected by the gravitational field of this black hole. (orig.)

  8. The use and disposal of household pesticides

    International Nuclear Information System (INIS)

    Grey, Charlotte N.B.; Nieuwenhuijsen, Mark J.; Golding, Jean

    2005-01-01

    Most pesticides are synthetic chemicals manufactured specifically for their toxic properties to the target species, and widely used globally. Several epidemiological studies in the United States have suggested health concerns arising from the chronic exposure of young children to pesticides in the domestic environment. In the UK very little is currently known about how nonoccupational pesticides are being used or disposed of. Any use of pesticides is a potential risk factor for children's exposure, and any potential exposure is likely to be reduced by the parents' adopting precautionary behaviour when using these pesticide products. This was investigated using a sample of 147 parents from the Avon Longitudinal Study of Parents and Children cohort in and around Bristol, through an in-depth interview between August and November 2001. The results of this study add to the understanding of the underlying behaviour of parents applying pesticide products in the home environment in the UK. Pesticides are readily available, and are normally purchased in do-it-yourself shops and supermarkets and mostly disposed of in domestic waste. Safety was stated by 45% of parents to be the most important factor to consider when buying a pesticide. When buying pesticide products, labels were stated to be the most important source of information about pesticides. However, a third of parents stated they would not follow the product label exactly when using a product, just under half felt labels were both inadequate and hard to understand, and about 10% of parents would not take notice of warnings on the pesticide label. Less than half of parents would use gloves when applying a pesticide, although the use of protective equipment such as gloves during the application of pesticides could greatly reduce the exposure. It is a public health concern that the instructions on the labels of products may not always be understood or followed, and further understanding of user behaviour is needed

  9. Co-crystal of (R,R)-1,2-cyclohexanediol with (R,R)-tartaric acid, a key structure in resolution of the ({+-})-trans-diol by supercritical extraction, and the related ternary phase system

    Energy Technology Data Exchange (ETDEWEB)

    Thorey, Paul [Department of Chemical and Environmental Process Engineering, Budapest University of Technology and Economics, H-1521 Budapest (Hungary); Bombicz, Petra [Institute of Structural Chemistry, Chemical Research Center, Hungarian Academy of Science, H-1525 Budapest (Hungary); Szilagyi, Imre Miklos [Material Structure and Modeling Research Group, Hungarian Academy of Sciences, H-1111 Budapest (Hungary); Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, H-1521 Budapest (Hungary); Molnar, Peter; Bansaghi, Gyoergy; Szekely, Edit; Simandi, Bela [Department of Chemical and Environmental Process Engineering, Budapest University of Technology and Economics, H-1521 Budapest (Hungary); Parkanyi, Laszlo [Institute of Structural Chemistry, Chemical Research Center, Hungarian Academy of Science, H-1525 Budapest (Hungary); Pokol, Gyoergy [Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, H-1521 Budapest (Hungary); Madarasz, Janos, E-mail: madarasz@mail.bme.hu [Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, H-1521 Budapest (Hungary)

    2010-01-10

    A novel co-crystal of trans-(R,R)-1,2-cyclohexanediol and (R,R)-tartaric acid (with 1:1 molar ratio, 1) has been found to be a key crystalline compound in the improved resolution of ({+-})-trans-1,2-cyclohexanediol by supercritical fluid extraction. The molecular and crystal structure of this co-crystal, which crystallizes in orthorhombic crystal system (space group P2{sub 1}2{sub 1}2{sub 1}, a = 6.7033(13) A, b = 7.2643(16), c = 24.863(5), Z = 4), has been solved by single crystal X-ray diffraction (R = 0.064). The packing arrangement consists of two dimensional layers of sandwich-like sheets, where the inner part is constructed by double layers of tartaric acids which hydrophilicity is 'covered' on both upper and bottom side by cyclohexanediols with the hydrophobic cyclohexane rings pointing outward. Thus, a rather complex hydrogen bonding pattern is constructed. The relatively high melting point (133 {sup o}C) observed by both simultaneous TG/DTA and DSC, and the main features of FTIR-spectrum of 1 are explained by the increased stability of this crystal structure. DSC studies on binary mixtures of co-crystal 1 with (R,R)-1,2-cyclohexanediol or (R,R)-tartaric acid, revealed eutectic temperatures of T{sub eu} = 100 or 131 {sup o}C, respectively. Between (S,S)-1,2-cyclohexanediol and (R,R)-tartaric acid a eutectic temperature of T{sub eu} = 85 {sup o}C have also been observed. The phase relations have been confirmed by powder X-ray diffraction, as well.

  10. Training Manual Occupational Pesticide Exposure & Health and Safe & Responsible Handling of Pesticides

    NARCIS (Netherlands)

    Maden, van der E.C.L.J.; Koomen, I.

    2016-01-01

    Pesticides are commonly used in the horticulture sector. While emphasis is often on the correct and efficient application of pesticides, the risk associated with application of pesticides receives less attention. Those working with pesticides need to know about occupational pesticide exposure and

  11. Water and Pesticides

    Science.gov (United States)

    ; Environment Human Health Animal Health Safe Use Practices Food Safety Environment Air Water Soil Wildlife Home Page Pesticides and the Environment Water and Pesticides Related Topics: What Happens to Pesticides Released into the Environment? Water Solubility Drinking Water and Pesticides Fact Sheet

  12. Seasonal Adjustment with the R Packages x12 and x12GUI

    Directory of Open Access Journals (Sweden)

    Alexander Kowarik

    2014-12-01

    The provision of the powerful X-12-ARIMA seasonal adjustment program available directly from within R, as well as of the new facilities for marking outliers, batch processing and change tracking, makes the package a potent and functional tool.

  13. Self-concept of children with cerebral palsy measured using the population-specific myTREEHOUSE Self-Concept Assessment.

    Science.gov (United States)

    Cheong, Sau Kuan; Lang, Cathryne P; Johnston, Leanne M

    2018-02-01

    Self-concept is an individual's perception of him/herself. Research into the self-concept of children with cerebral palsy (CP) has been sparse due to the lack of a population-specific self-concept instrument. Using the new myTREEHOUSE Self-Concept Assessment, this study investigated the self-concept of children with CP in relation to age, gender, motor, communication and cognitive function. Children with CP aged 8-12 years (n = 50; 29 males; mean 10 years 2 months; GMFCS-E&R I = 36, II = 8, III = 5, IV = 1) completed myTREEHOUSE and a standardised intelligence measure. Most children reported positive self-concept from all three myTREEHOUSE Performance Perspectives and over half (60%) fell within the Low range for the Personal Concern Score. Self-concept was not associated with age, gender, motor function, or communication function. However, for cognitive function, associations were observed for Social Skills (Below Average > Average cognitive function; Cohen's d = 1.07) and Learning Skills (Above Average > Average cognitive function; Cohen's d = 0.95) domains when rated from a Personal Performance Perspective. As the first study of the self-concept of children with CP using a CP-specific assessment, this study offers important insights into what children with CP think about themselves. Generally, the self-concept of children with CP was sound. Future research on environmental facilitators and barriers to robust self-concept development is recommended. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Pesticide poisoning in Chitwan, Nepal: a descriptive epidemiological study

    Directory of Open Access Journals (Sweden)

    Deepak Gyenwali

    2017-07-01

    Full Text Available Abstract Background Globally, there is a growing concern over pesticides use, which has been linked to self-harm and suicide. However, there is paucity of research on the epidemiology of pesticides poisoning in Nepal. This study is aimed at assessing epidemiological features of pesticides poisoning among hospital-admitted cases in selected hospitals of Chitwan District of Nepal. Methods A hospital-based quantitative study was carried out in four major hospitals of Chitwan District. Information on all pesticides poisoning cases between April 1 and December 31, 2015, was recorded by using a Pesticides Exposure Record (PER form. Results A total of 439 acute pesticides poisoning cases from 12 districts including Chitwan and adjoining districts attended the hospitals during the 9-month-long study period. A majority of the poisoned subjects deliberately used pesticides (89.5% for attempted suicide. The total incidence rate was 62.67/100000 population per year. Higher annual incidence rates were found among young adults (111.66/100000 population, women (77.53/100000 population and individuals from Dalit ethnic groups (98.22/100000 population. Pesticides responsible for poisoning were mostly insecticides (58.0% and rodenticides (20.8%. The most used chemicals were organophosphates (37.3% and pyrethroids (36.7%. Of the total cases, 98.6% were hospitalized, with intensive care required for 41.3%. The case fatality rate among admitted cases was 3.8%. Conclusions This study has indicated that young adults, females and socially disadvantaged ethnic groups are at a higher risk of pesticides poisoning. Pesticides are mostly misused intentionally as an easy means for committing suicide. It is recommended that the supply of pesticides be properly regulated to prevent easy accessibility and misuse. A population-based study is warranted to reveal the actual problem of pesticides exposure and intoxication in the community.

  15. Pesticide exposure and lymphohaematopoietic cancers: a case-control study in an agricultural region (Larissa, Thessaly, Greece).

    Science.gov (United States)

    Kokouva, Maria; Bitsolas, Nikolaos; Hadjigeorgiou, Georgios M; Rachiotis, George; Papadoulis, Nikolaos; Hadjichristodoulou, Christos

    2011-01-04

    The causality of lymphohaematopoietic cancers (LHC) is multifactorial and studies investigating the association between chemical exposure and LHC have produced variable results. The aim of this study was to investigate the relationships between exposure to pesticides and LHC in an agricultural region of Greece. A structured questionnaire was employed in a hospital-based case control study to gather information on demographics, occupation, exposure to pesticides, agricultural practices, family and medical history and smoking. To control for confounders, backward conditional and multinomial logistic regression analyses were used. To assess the dose-response relationship between exposure and disease, the chi-square test for trend was used. Three hundred and fifty-four (354) histologically confirmed LHC cases diagnosed from 2004 to 2006 and 455 sex- and age-matched controls were included in the study. Pesticide exposure was associated with total LHC cases (OR 1.46, 95% CI 1.05-2.04), myelodysplastic syndrome (MDS) (OR 1.87, 95% CI 1.00-3.51) and leukaemia (OR 2.14, 95% CI 1.09-4.20). A dose-response pattern was observed for total LHC cases (P = 0.004), MDS (P = 0.024) and leukaemia (P = 0.002). Pesticide exposure was independently associated with total LHC cases (OR 1.41, 95% CI 1.00 - 2.00) and leukaemia (OR 2.05, 95% CI 1.02-4.12) after controlling for age, smoking and family history (cancers, LHC and immunological disorders). Smoking during application of pesticides was strongly associated with total LHC cases (OR 3.29, 95% CI 1.81-5.98), MDS (OR 3.67, 95% CI 1.18-12.11), leukaemia (OR 10.15, 95% CI 2.15-65.69) and lymphoma (OR 2.72, 95% CI 1.02-8.00). This association was even stronger for total LHC cases (OR 18.18, 95% CI 2.38-381.17) when eating simultaneously with pesticide application. Lymphohaematopoietic cancers were associated with pesticide exposure after controlling for confounders. Smoking and eating during pesticide application were identified as

  16. 77 FR 69840 - Iodomethane; Notice of Receipt of Request to Voluntarily Cancel Iodomethane Pesticide...

    Science.gov (United States)

    2012-11-21

    ... of Request to Voluntarily Cancel Iodomethane Pesticide Registrations and Amend a Registration AGENCY... voluntarily cancel the registrations of products containing the pesticide iodomethane. In addition, the... deadline identified. [[Page 69841

  17. Application of the Raman spectroscopy for the characterization of organic pesticides

    International Nuclear Information System (INIS)

    Sato B, R.Y.; Medina G, C.; Medina V, J.; Frausto R, C.

    2004-01-01

    Raman spectra of organophosphate, organo chlorine and bipyridyl pesticides are presented in this study. They have been obtained satisfactorily by the NlR-Raman spectroscopy technique. Pesticides have been analyzed in solution or as a solid in glass containers and on aluminum substrates. This analytic technique can be an alternative tool for the detection of pesticides in the agriculture, presenting advantages as be quick, not destructive and require little or no sample preparation. Moreover, samples can be analyzed through transparent containers avoiding contact with the toxic substances. The implementation of the aluminium substrate is easy and practical. Moreover, it is commercially available and does not need a previous preparation. The analysis of a mixture of two pesticides in a β carotene solution is shown. (Author) 25 refs., 8 figs

  18. 77 FR 32978 - Exxon Valdez Oil Spill Trustee Council; Notice of Meeting

    Science.gov (United States)

    2012-06-04

    ... Hall Conference Room, 4210 University Drive, Anchorage, Alaska. FOR FURTHER INFORMATION CONTACT... R. Taylor, Director, Office of Environmental Policy and Compliance. [FR Doc. 2012-13380 Filed 6-1-12...

  19. Pesticides

    Science.gov (United States)

    ... stores. Exposure to pesticides can happen in the workplace, through foods that are eaten, and in the ... or place bait in areas where children or pets have access. DO NOT stock up on pesticides, ...

  20. 6,6'-(1E,1'E-((1R,2R-1,2-Diphenylethane-1,2-diylbis(azan-1-yl-1-ylidenebis(methan-1-yl-1-ylidenebis(2-tert-butyl-4-((trimethylsilylethynylphenol

    Directory of Open Access Journals (Sweden)

    David Díaz Díaz

    2013-03-01

    Full Text Available Functionalizable salen derivative, 6,6'-(1E,1'E-((1R,2R-1,2-diphenylethane-1,2-diylbis(azan-1-yl-1-ylidenebis(methan-1-yl-1-ylidenebis(2-tert-butyl-4-((trimethylsilyl ethyn-ylphenol (3, was synthesized by condensation between (1R,2R-1,2-diphenylethane-1,2-diamine (2 and 3-tert-butyl-2-hydroxy-5-((trimethylsilylethynyl benzaldehyde (1 under refluxing conditions. The title compound was characterized by 1H-NMR, 13C-NMR, FT-IR, high-resolution mass spectrometry, optical rotation and melting point determination.

  1. Residue levels and risk assessment of pesticides in nuts of China.

    Science.gov (United States)

    Liu, Yihua; Shen, Danyu; Li, Shiliang; Ni, Zhanglin; Ding, Ming; Ye, Caifen; Tang, Fubin

    2016-02-01

    The pesticide residue levels of three nuts (chestnut, walnut, pinenut) collected from seven main producing areas of China were investigated. Twenty-nine pesticides, including organophosphates (OPs), organochlorines (OCs), pyrethroids (PYs) and two fungicides (triadimefon and buprofezin) were analyzed by gas chromatography (GC). Four OPs (acephate, dimethoate, chlorpyrifos and parathion-methyl) were found in 11.4% samples, with the concentrations of 19.0 µg kg(-1) to 74.0 µg kg(-1). Six OCs (DDT, HCH, endosulfan, quintozene, aldrin and dieldrin) were found in 18.2% samples, with the concentrations of 2.0 µg kg(-1) to 65.7 µg kg(-1). Among OCs, p,p-DDE and α-HCH were the dominant isomer for DDT and HCH. Five PYs (fenpropathrin, fenvalerate, cypermethrin, bifenthrin and cyhalothrin) were found in 15.9% samples, with the concentrations of 2.5 µg kg(-1) to 433.0 µg kg(-1). Fenpropathrin was the most frequently detected pesticide. In addition, triadimefon and buprofezin were detected only in two samples. For the tested nuts, 25.0% samples with multiple residues (containing more than two pesticides) were noted, even up to 9.1% samples with five pesticide residues. The residue of 15.9% samples was higher than the maximum residue limits (MRLs) of China. The short-term risks for the tested nuts were below 1.2%, and the highest long-term risk was 12.58%. The cumulative risk (cHI) for the tested pesticides were 8.43% (OPs), 0.42% (OCs), 12.82% (PYs) and 0.15% (fungicides), respectively. The total cHI was 21.82%. There was no significant health risk for consumers via nuts consumption. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Little field evidence of direct acute and short-term effects of current pesticides on the grey partridge.

    Science.gov (United States)

    Millot, Florian; Berny, Philippe; Decors, Anouk; Bro, Elisabeth

    2015-07-01

    Direct lethal and sublethal effects of pesticides on farmland birds' populations are recurring questions and largely debated. In this context, we conducted an innovative study combining radiotelemetry, farmer surveys, residue analyses on carcasses and modelling to assess the unintentional effects of pesticides on terrestrial birds. We chose the grey partridge Perdix perdix as a case study because this typical bird of European cereal ecosystems is highly exposed to pesticides. In this paper we focused on acute and short-term impacts of pesticides on adult mortality during spring and summer in a one-substance approach (multiple exposure were not studied here) but for a large variety of active substances (a.s.) actually used in cultivated farmland of Northern France. The fate and the location of 529 partridges were monitored twice a day from early March to late August 2010 and 2011 on 12 sites (14,500 ha). Their daily potential exposure to 183 a.s. was determined by overlapping birds' habitat use and daily pesticide application data. Based on this procedure, we calculated mortality rates within 10 days following a potential exposure for 157 different a.s.. 5 a.s. were associated with a "10-day mortality rate" higher than 10% but a single one (thiacloprid) is reported to be highly toxic to birds. We recorded 261 mortalities among which 94 carcasses were in suitable condition for residue analyses. We detected at least one a.s in 39.4% of carcasses. However, only 2 mortality cases were attributed to poisoning (carbofuran). Furthermore, modelling results showed that these lethal pesticide-related poisonings decreased the population growth rate by less than 1%. In conclusion, we did not point out important direct acute and short-term effects of pesticides currently used by farmers during the breeding season on the grey partridge. This is discussed with regards to the complexity of potential effects in operational conditions. Copyright © 2015 Elsevier Inc. All rights

  3. General f(R and conformal inflation from minimal supergravity plus matter

    Directory of Open Access Journals (Sweden)

    Horatiu Nastase

    2016-02-01

    Full Text Available We embed general f(R inflationary models in minimal supergravity plus matter, a single chiral superfield Φ, with or without another superfield S, via a Jordan frame Einstein+scalar description. In particular, inflationary models like a generalized Starobinsky one are analyzed and constraints on them are found. We also embed the related models of conformal inflation, also described as Jordan frame Einstein+scalar models, in particular the conformal inflation from the Higgs model, and analyze the inflationary constraints on them.

  4. 75 FR 6112 - Approval and Promulgation of Air Quality Implementation Plans; Georgia: Update to Materials...

    Science.gov (United States)

    2010-02-08

    ...) Incinerators........ 6/15/98 12/2/99, 64 FR 67491 391-3-1-.02(2)(d) Fuel-burning 1/17/79 9/18/79, 44 FR 54047...-.02(2)(aa) VOC Emissions from 1/9/91 10/13/92, 57 FR 46780 Wire Coating. 391-3-1-.02(2)(bb) Petroleum...)(lll) NOX Emissions from 2/16/00 7/10/01, 66 FR 35906 Fuel-burning Equipment. 391-3-1-.02(2)(mmm) NOX...

  5. 75 FR 71693 - Pesticide Program Dialogue Committee; Announcement of New Membership and Notice of Public Meetings

    Science.gov (United States)

    2010-11-24

    ... farmers; pesticide industry and trade associations; environmental, consumer, and farmworker groups; animal... PPDC: Pesticide industry and trade associations; environmental/public interest, consumer, and animal rights groups; farm worker organizations; pesticide user, grower, and commodity groups; Federal and State...

  6. Effectiveness of Commercial and Homemade Washing Agents in Removing Pesticide Residues on and in Apples.

    Science.gov (United States)

    Yang, Tianxi; Doherty, Jeffery; Zhao, Bin; Kinchla, Amanda J; Clark, John M; He, Lili

    2017-11-08

    Removal of pesticide residues from fresh produce is important to reduce pesticide exposure to humans. This study investigated the effectiveness of commercial and homemade washing agents in the removal of surface and internalized pesticide residues from apples. Surface-enhanced Raman scattering (SERS) mapping and liquid chromatography tandem mass spectrometry (LC-MS/MS) methods were used to determine the effectiveness of different washing agents in removing pesticide residues. Surface pesticide residues were most effectively removed by sodium bicarbonate (baking soda, NaHCO 3 ) solution when compared to either tap water or Clorox bleach. Using a 10 mg/mL NaHCO 3 washing solution, it took 12 and 15 min to completely remove thiabendazole or phosmet surface residues, respectively, following a 24 h exposure to these pesticides, which were applied at a concentration of 125 ng/cm 2 . LC-MS/MS results showed, however, that 20% of applied thiabendazole and 4.4% of applied phosmet had penetrated into the apples following the 24 h exposure. Thiabendazole, a systemic pesticide, penetrated 4-fold deeper into the apple peel than did phosmet, a non-systemic pesticide, which led to more thiabendazole residues inside the apples, which could not be washed away using the NaHCO 3 washing solution. This study gives us the information that the standard postharvest washing method using Clorox bleach solution for 2 min is not an effective means to completely remove pesticide residues on the surface of apples. The NaHCO 3 method is more effective in removing surface pesticide residues on apples. In the presence of NaHCO 3 , thiabendazole and phosmet can degrade, which assists the physical removal force of washing. However, the NaHCO 3 method was not completely effective in removing residues that have penetrated into the apple peel. The overall effectiveness of the method to remove all pesticide residues diminished as pesticides penetrated deeper into the fruit. In practical application

  7. Soil and Pesticides

    Science.gov (United States)

    ; Environment Human Health Animal Health Safe Use Practices Food Safety Environment Air Water Soil Wildlife Home Page Pesticides and the Environment Soil and Pesticides Related Topics: What Happens to Pesticides español Soil and Pesticides Soil can be degraded and the community of organisms living in the soil can

  8. Pesticide risk assessment in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Richard N [Environmental Protection Agency, Washington, DC (United States)

    1992-07-01

    In recognition of potential risks, all pesticides distributed and sold in the United States must fulfil extensive registration requirements for the Environmental Protection Agency (EPA). Registration is a licensing procedure where industry must submit data to demonstrate the safety of pesticidal substances and products before they can be used commercially. The regulatory control of pesticides is unique among chemicals in the U.S. in that testing beyond initial registration may be imposed by the Agency throughout the commercial life of the chemical, as long as there is adequate justification. Registration requirements are gauged to the nature of potential exposures. For instance, more data are generally needed for food use registrations than for non-food uses because of direct consumption of treated foods by the whole U.S. population. Unlike pesticide practices in many countries and authorities, as in the European Community where agricultural pesticides, non-agricultural pesticides and genetically engineered microbial agents are handled by separate directives, all pesticide activities are covered in the U.S. by the Federal Insecticide, Fungicide and Rodenticide Act. This statute covers pesticide uses on foods and animal feed and a number of non-food applications like forest and horticultural uses, residential lawn care, in-home applications, and disinfectants/sterilants. Traditional inorganic and organic chemicals are covered, as well as biological agents like pheromones. Naturally occurring and genetically altered microorganisms also come under the definition of pesticides, but multicellular animals are exempt from regulation as pesticides. Pesticide registration in the U.S. as in many other countries may be a long-term, resource intensive undertaking. Not uncommonly the process from beginning to complete registration may take 4 to 10 years and cost about $10 million. To meet the responsibilities of reviewing studies, overseeing 400 active ingredients and 35

  9. Pesticide risk assessment in the United States

    International Nuclear Information System (INIS)

    Hill, Richard N.

    1992-01-01

    In recognition of potential risks, all pesticides distributed and sold in the United States must fulfil extensive registration requirements for the Environmental Protection Agency (EPA). Registration is a licensing procedure where industry must submit data to demonstrate the safety of pesticidal substances and products before they can be used commercially. The regulatory control of pesticides is unique among chemicals in the U.S. in that testing beyond initial registration may be imposed by the Agency throughout the commercial life of the chemical, as long as there is adequate justification. Registration requirements are gauged to the nature of potential exposures. For instance, more data are generally needed for food use registrations than for non-food uses because of direct consumption of treated foods by the whole U.S. population. Unlike pesticide practices in many countries and authorities, as in the European Community where agricultural pesticides, non-agricultural pesticides and genetically engineered microbial agents are handled by separate directives, all pesticide activities are covered in the U.S. by the Federal Insecticide, Fungicide and Rodenticide Act. This statute covers pesticide uses on foods and animal feed and a number of non-food applications like forest and horticultural uses, residential lawn care, in-home applications, and disinfectants/sterilants. Traditional inorganic and organic chemicals are covered, as well as biological agents like pheromones. Naturally occurring and genetically altered microorganisms also come under the definition of pesticides, but multicellular animals are exempt from regulation as pesticides. Pesticide registration in the U.S. as in many other countries may be a long-term, resource intensive undertaking. Not uncommonly the process from beginning to complete registration may take 4 to 10 years and cost about $10 million. To meet the responsibilities of reviewing studies, overseeing 400 active ingredients and 35

  10. Effect of pesticide mixture on value of fresh, fermented and pickles cucumbers

    Directory of Open Access Journals (Sweden)

    Krystyna WElkner

    2013-12-01

    Full Text Available In years 1998-1999 effects of fungicides (azoxystrobin and copper hydroxide, insecticides (etafenproks and pirimicarb and their mixtures on chemical composition and organoleptic quality of fresh, fermented and pickled cucumbers were studied_ To analyses fruits were taken after 7 and 12 days from treatment. Fresh cucumber fruits after 7 days from treatment with investigated pesticides contained less carbohydrates and ascorbic acids and higher level of nitrates in compare to untreated fruits (control. After 12 days from treatment the differences between treated and untreated fruits dissapeared. Cucumber fruits harvested 7 and 12 days after treatment were processed separately. Quality evaluation of fermented and pickled cucumbers was carried out 4 months after processing. In most of cucumber fruits (7 days after treatment with pesticides treated with pesticides empty cavities were found, and not in control (untreated. Number of cavities was highest in fresh and pickled cucumbers treated with mixture of fungicide and insecticide. In case of fermented cucumbers highest number of empty cavities occurred in fruits treated with fungicide azoxystrobin. Cucumber fruits taken to fermentation process 7 days after day of treatment had darker green colour, lowered haIdness, and larger empty cavities than untreated fruits. In fruits harvested 12 days after pesticides application such differencess were not observed.

  11. PON1Q192R genetic polymorphism modifies organophosphorous pesticide effects on semen quality and DNA integrity in agricultural workers from southern Mexico

    International Nuclear Information System (INIS)

    Perez-Herrera, N.; Polanco-Minaya, H.; Salazar-Arredondo, E.; Solis-Heredia, M.J.; Hernandez-Ochoa, I.; Rojas-Garcia, E.; Alvarado-Mejia, J.; Borja-Aburto, V.H.; Quintanilla-Vega, B.

    2008-01-01

    Pesticide exposure, including organophosphorous (OP) insecticides, has been associated with poor semen quality, and paraoxonase (PON1), an enzyme involved in OP deactivation, may have a role on their susceptibility, due to PON1 polymorphisms. Our objective was to evaluate the role of PON1Q192R polymorphism on the susceptibility to OP toxicity on semen quality and DNA integrity in agricultural workers. A cross-sectional study was conducted in farmers with Mayan ascendancy from southeastern Mexico chronically exposed to pesticides; mostly OP. Fifty four agricultural workers (18-55 years old) were included, who provided semen and blood samples. Semen quality was evaluated according to WHO, sperm DNA damage by in situ-nick translation (NT-positive cells), PON1Q192R polymorphism by real-time PCR and serum PON1 activity by using phenylacetate and paraoxon. Two OP exposure indexes were created: at the month of sampling and during 3 months before sampling, representing the exposure to spermatids-spermatozoa and to cells at one spermatogenic cycle, respectively. PON1 192R and 192Q allele frequencies were 0.54 and 0.46, respectively. Significant associations were found between OP exposure at the month of sampling and NT-positive cells and sperm viability in homozygote 192RR subjects, and dose-effect relationships were observed between OP exposure during 3 months before sampling and sperm quality parameters and NT-positive cells in homozygote 192RR farmers. This suggests that cells at all stages of spermatogenesis are target of OP, and that there exists an interaction between OP exposure and PON1Q192R polymorphism on these effects; farmers featuring the 192RR genotype were more susceptible to develop reproductive toxic effects by OP exposure

  12. 21 CFR 344.12 - Ear drying aid active ingredient.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Ear drying aid active ingredient. 344.12 Section 344.12 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... alcohol 95 percent in an anhydrous glycerin 5 percent base. [65 FR 48905, Aug. 10, 2000] ...

  13. Extraction of Botanical Pesticides from Pelargonium graveolens using Supercritical Carbon Dioxide

    Czech Academy of Sciences Publication Activity Database

    Machalová, Zdeňka; Sajfrtová, Marie; Pavela, R.; Topiař, Martin

    2015-01-01

    Roč. 67, MAY (2015), s. 310-317 ISSN 0926-6690 R&D Projects: GA TA ČR TA01010578 Institutional support: RVO:67985858 Keywords : botanical pesticides * geranium oil * supercritical fluid extraction Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 3.449, year: 2015

  14. Pesticides and the Environment

    Science.gov (United States)

    ; Environment Human Health Animal Health Safe Use Practices Food Safety Environment Air Water Soil Wildlife Home Page Pesticides and the Environment Related Topics: What Happens to Pesticides Released into the Environment? Pesticide Storage Pesticide Disposal Pesticide Products Integrated Pest Management (IPM) How Safe

  15. Mineralization of 14C-labelled aromatic pesticide molecules in Egyptian soils under aerobic and anaerobic conditions

    International Nuclear Information System (INIS)

    Zayed, S.M.A.D.; Earghaly, M.; Mahdy, F.; El-Maghraby, S.; Taha, H.; Soliman, S.M.

    2001-01-01

    The mineralization of 2,4-D, carbofuran and pirimiphos-methyl in Egyptian soils was studied over a period of 90 days. Laboratory studies under aerobic and anaerobic conditions were conducted using 14 C-ring labelled pesticides. Under anaerobic conditions 10-14% of applied ring labelled 2,4-D mineralized during 90 days with no significant variations due to soil type. Under aerobic conditions, 2,4-D mineralized more readily in clay soil to reach 29-34% of applied dose within 90 days. In clay loam soil, 14 C-carbofuran and 14 C-pirimiphos-methyl mineralized at a rather slow rate to reach 12-14% and 12-13% of applied dose in 90 days, respectively under aerobic conditions. Generally, soils repeatedly treated with pesticides gave a slightly lower percentage of mineralization than control soils. In all studies, the soil extractable pesticide residues decreased with time and the bound residues gradually increased. The highest binding affinity of about 26-29% was observed with 2,4-D in clay soil under aerobic conditions in 90 days. Carbofuran, and pirimiphos-methyl, on the other hand, had lower binding capacity that did not exceed 16% of applied radioactivity. (author)

  16. Effect of Pumping Strategies on Pesticide Concentrations in Water Abstraction Wells

    DEFF Research Database (Denmark)

    Aisopou, Angeliki; Bjerg, Poul Løgstrup; Albrechtsen, Hans-Jørgen

    Pesticide use in agriculture is one of the main sources of groundwater contamination and poses an important threat to groundwater abstraction. Pesticides have been detected in 37% of Danish monitoring wells sampled, with 12 % exceeding drinking water guidelines. Field data captured in monitoring...... and pumping wells show that pesticide concentrations vary greatly in both time and space. This study aimed to use models to determine how pumping affects pesticide concentrations in drinking water wells placed in two hypothetical aquifer systems; a homogeneous layered aquifer and a layered aquifer...... in a pumping well capture zone were constructed using COMSOL Multiphysics. A series of simulations were conducted to examine the effect of pumping strategies (constant versus varying pumping rate), pesticide properties and aquifer hydrogeology on the concentration in drinking water wells. The results...

  17. Pattern of pesticide storage before pesticide self-poisoning in rural Sri Lanka

    Science.gov (United States)

    Mohamed, Fahim; Manuweera, Gamini; Gunnell, David; Azher, Shifa; Eddleston, Michael; Dawson, Andrew; Konradsen, Flemming

    2009-01-01

    Background Deliberate self-poisoning with agricultural pesticides is the commonest means of suicide in rural Asia. It is mostly impulsive and facilitated by easy access to pesticides. The aim of this large observational study was to investigate the immediate source of pesticides used for self-harm to help inform suicide prevention strategies such as reducing domestic access to pesticides. Methods The study was conducted in a district hospital serving an agricultural region of Sri Lanka. Patients who had self-poisoned with pesticides and were admitted to the adult medical wards were interviewed by study doctors following initial resuscitation to identify the source of pesticides they have ingested. Results Of the 669 patients included in the analysis, 425 (63.5%) were male; the median age was 26 (IQR 20-36). In 511 (76%) cases, the pesticides had been stored either inside or immediately outside the house; among this group only eight patients obtained pesticides that were kept in a locked container. Ten percent (n = 67) of the patients used pesticides stored in the field while 14% (n = 91) purchased pesticides from shops within a few hours of the episode. The most common reasons for choosing the particular pesticide for self-harm were its easy accessibility (n = 311, 46%) or its popularity as a suicide agent in their village (n = 290, 43%). Conclusion Three quarters of people who ingested pesticides in acts of self-harm used products that were available within the home or in close proximity; relatively few patients purchased the pesticide for the act. The study highlights the importance of reducing the accessibility of toxic pesticides in the domestic environment. PMID:19889236

  18. 75 FR 56107 - Product Cancellation Order for Certain Pesticide Registrations

    Science.gov (United States)

    2010-09-15

    ..., human health, and agricultural advocates; the chemical industry; pesticide users; and members of the... Piperonyl butoxide, Institutional Bug Pyrethrins. Killer. 019713-00315 Pearson's Grain Piperonyl butoxide...

  19. 76 FR 55272 - Flubendiamide; Pesticide Tolerances; Technical Amendment

    Science.gov (United States)

    2011-09-07

    ... pesticide, flubendiamide in or on the meat and meat byproducts of cattle, goat, hog, horse, and sheep. The..., meat byproducts (0.08 ppm); goat, meat (0.60 ppm); goat, meat byproducts (0.08 ppm); hog, meat (0.15.... Section 180.639(a)(2) is amended by revising the entries for cattle, meat; cattle, meat byproducts; goat...

  20. ESTIMATION OF THE BURDEN OF PESTICIDE RESIDUES IN SLOVAK POPULATION

    Directory of Open Access Journals (Sweden)

    Jozef Sokol

    2010-07-01

    Full Text Available Pesticides used in the agriculture have to be applied according to the requirements of good agricultural practice and appropriate law. Pesticides leave detectable residues in agricultural crops, raw materials and ecosystem components. Pesticides reach the human population through the food chain. Information on the type and concentration of pesticide residues in food is in Slovakia collected trough the monitoring programs. Health risks associated with pesticides contaminants in human nutrition are very important and are recently studied by several expert groups. Prerequisite programs are necessary to protect public health. Risk analysis and monitoring of the population burden by pesticide contaminants have to be performed in expert level. The general strategy for assessment of toxicity of pesticides is listed by the World health Organisation. Scientific risk assessment is the basis for taking action and making the legislation at national and European community level.doi:10.5219/69

  1. Alterations in the fatty acid profile, antioxidant enzymes and protein pattern of Biomphalaria alexandrina snails exposed to the pesticides diazinon and profenfos.

    Science.gov (United States)

    Bakry, Fayez A; El-Hommossany, Karem; Abd El-Atti, Mahmoud; Ismail, Somaya M

    2016-04-01

    The use of pesticides is widespread in agricultural activities. These pesticides may contaminate the irrigation and drainage systems during agriculture activities and pests' control and then negatively affect the biotic and a biotic component of the polluted water courses. The present study aimed to evaluate the effect of the pesticides diazinon and profenfos on some biological activities of Biomphalaria alexandrina snails such as fatty acid profile, some antioxidant enzymes (thioredoxin reductase (TrxR), sorbitol dehydrogenase (SDH), superoxide dismutase (SOD), catalase (CAT) as well as glutathione reductase (GR) and lipid peroxidation (LP)) and protein patterns in snails' tissues exposed for 4 weeks to LC10 of diazinon and profenfos. The results showed that the two pesticides caused considerable reduction in survival rates and egg production of treated snails. Identification of fatty acid composition in snail tissues treated with diazinon and profenfos pesticides was carried out using gas-liquid chromatography (GLC). The results declared alteration in fatty acid profile, fluctuation in percentage of long chain and short chain fatty acid contributions either saturated or unsaturated ones, and a decrease in total lipid content in tissues of snails treated with these pesticides. The data demonstrate that there was a significant inhibition in the activities of tissues SOD, CAT, glutathione reductase (GR), TrxR, and SDH in tissues of treated snails, while a significant elevation was detected in LP as compared to the normal control. On the other hand, the electrophoretic pattern of total protein showed differences in number and molecular weights of protein bands due to the treatment of snails. It was concluded that the residues of diazinon and profenfos pesticides in aquatic environments have toxic effects onB. alexandrina snails. © The Author(s) 2013.

  2. Pesticides and Population Declines of California Alpine Frogs

    Science.gov (United States)

    Airborne pesticides from the Central Valley of California have been implicated as a cause for population declines of several amphibian species, with the strongest evidence for the mountain yellow-legged frog complex (Rana muscosa and R. sierrae) in the Sierra Nevada. We measured ...

  3. Glycosylation of alpha(2)delta(1) subunit: a sweet talk with Ca(v)1.2 channels

    Czech Academy of Sciences Publication Activity Database

    Lazniewska, Joanna; Weiss, Norbert

    2016-01-01

    Roč. 35, č. 3 (2016), s. 239-242 ISSN 0231-5882 R&D Projects: GA ČR GA15-13556S; GA MŠk 7AMB15FR015 Institutional support: RVO:61388963 Keywords : calcium channel * Ca(v)1.2 channel * ancillary subunit * alpha(2)delta(1) subunit * glycosylation * trafficking Subject RIV: CE - Biochemistry Impact factor: 1.170, year: 2016

  4. The reaction 12C + 12C at bombarding energies from 5 to 10 MeV per nucleon

    International Nuclear Information System (INIS)

    Morsad, A.

    1986-01-01

    The reaction 12 C + 12 C has been studied for energies ranging from E LAB = 60 to 120 MeV. The excitation functions and angular distributions were obtained for the elastic (0 + , 0 + ) and inelastic (2 + , 0 + ), (2 + , 2 + ) channels as well as for the transfer channels of one and two nucleons. For the transfer reactions, the feeding of the final bound states was very selective. Narrow correlated structures were found in the transfer and especially in the elastic and inelastic channels. In this energy range, there appears to be a transition from surface transparency to interference phenomena. The optical model in its simplest form is unable to describe the elastic scattering at large angles. This has been interpreted as a consequence of the coupling between the elastic and inelastic channels which is particularly strong of these energies. 80 refs [fr

  5. Constraining models of f(R) gravity with Planck and WiggleZ power spectrum data

    Science.gov (United States)

    Dossett, Jason; Hu, Bin; Parkinson, David

    2014-03-01

    In order to explain cosmic acceleration without invoking ``dark'' physics, we consider f(R) modified gravity models, which replace the standard Einstein-Hilbert action in General Relativity with a higher derivative theory. We use data from the WiggleZ Dark Energy survey to probe the formation of structure on large scales which can place tight constraints on these models. We combine the large-scale structure data with measurements of the cosmic microwave background from the Planck surveyor. After parameterizing the modification of the action using the Compton wavelength parameter B0, we constrain this parameter using ISiTGR, assuming an initial non-informative log prior probability distribution of this cross-over scale. We find that the addition of the WiggleZ power spectrum provides the tightest constraints to date on B0 by an order of magnitude, giving log10(B0) explanation.

  6. Effects of chemical and biological pesticides on plant growth parameters and rhizospheric bacterial community structure in Vigna radiata.

    Science.gov (United States)

    Singh, Sunil; Gupta, Rashi; Sharma, Shilpi

    2015-06-30

    With increasing application of pesticides in agriculture, their non-target effects on soil microbial communities are critical to soil health maintenance. The present study aimed to evaluate the effects of chemical pesticides (chlorpyrifos and cypermethrin) and a biological pesticide (azadirachtin) on growth parameters and the rhizospheric bacterial community of Vigna radiata. Qualitative and quantitative analysis by PCR-denaturing gradient gel electrophoresis (DGGE) and q-PCR, respectively, of the 16S rRNA gene and transcript were performed to study the impact of these pesticides on the resident and active rhizospheric bacterial community. While plant parameters were not affected significantly by the pesticides, a shift in the bacterial community structure was observed with an adverse effect on the abundance of 16S rRNA gene and transcripts. Chlorpyrifos showed almost complete degradation toward the end of the experiment. These non-target impacts on soil ecosystems and the fact that the effects of the biopesticide mimic those of chemical pesticides raise serious concerns regarding their application in agriculture. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Light induced heterogeneous ozone processing on the pesticides adsorbed on silica particles

    Science.gov (United States)

    Socorro, J.; Désert, M.; Quivet, E.; Gligorovski, S.; Wortham, H.

    2013-12-01

    In France, in 2010, the sales of pesticides reached 1.8 billion euros for 61 900 tons of active ingredients, positioning France as a first European consumer of pesticides, as reported by the European Crop Protection Association. About 19 million hectares of crops are sprayed annually with pesticides, i.e., 35% of the total surface area of France. This corresponds to an average pesticide dose of 3.2 kg ha-1. The consumption of herbicide and fungicide is favoured in comparison to the use of insecticides in France and the other European countries, as well. The partitioning of pesticides between the gas and particulate phases influences the atmospheric fate of these compounds such as their photo-chemical degradation. There is much uncertainty concerning the behavior of the pesticides in the atmosphere. Especially, there is a gap of knowledge concerning the degradation of the pesticides induced by heterogeneous reactions in absence and especially in presence of solar light. Considering that most of the pesticides currently used are semi-volatile, it is of crucial importance to investigate the heterogeneous reactivity of particulate pesticides with light and with atmospheric oxidants such as ozone and OH radical. The aim of the present work is to evaluate the light induced heterogeneous ozonation of suspended pesticide particles. 8 pesticides (cyprodinil, deltamethrin, difenoconazole, fipronil, oxadiazon, pendimethalin, permethrin and tetraconazole) were chosen for their physico-chemical properties and their concentration levels in the PACA (Région Provence-Alpes-Côte d'Azur) region, France. Silica particles with well-known properties were chosen as model particles of atmospheric relevance. Kinetic rate constants were determined to allow estimate the atmospheric lifetimes relating to ozone. The rate constants were determined as follows: k = (6.6 × 0.2) 10-19, (7.2 × 0.3) 10-19, (5.1 × 0.5) 10-19, (3.9 × 0.3) 10-19 [cm3 molecules-1 s-1] for Cyprodinil

  8. THE TREATED EGGSHELLS AS A NEW BIOSORBENT FOR ELIMINATION OF CARBARYL PESTICIDE FROM AQUEOUS SOLUTIONS: KINETICS, THERMODYNAMICS AND ISOTHERMS

    Directory of Open Access Journals (Sweden)

    ABDELHAMID BAKKA

    2016-10-01

    Full Text Available The efficiency of treated eggshells (TES for removing the carbaryl pesticide from aqueous solutions was examined by biosorption process. Batch mode experiments were conducted using various parameters such as contact time, temperature, biosorbent amount, carbaryl concentration and pH. Removal efficiency of carbaryl by the TES attained 87.35 % after 60 min of contact time, using 10 mg·L-1 of pesticide and 1.5 g·L-1 of biosorbent. The results indicate that Freundlich equation is well described with the carbaryl adsorption, with correlation coefficient R2 value of 0.99. They showed that the biosorption processes were spontaneous and exothermic. The Gibbs energy ∆G increased with increase in temperature indicating an increase in feasibility of biosorption at low temperature. These results show that treated eggshells can be employed as an alternative to commercial adsorbents in the removal of pesticides from aqueous solutions.

  9. Cosmological wheel of time: A classical perspective of f(R) gravity

    Science.gov (United States)

    Yadav, Bal Krishna; Verma, Murli Manohar

    It is shown that the structures in the universe can be interpreted to show a closed wheel of time, rather than a straight arrow. An analysis in f(R) gravity model has been carried out to show that due to local observations, a small arc at any given spacetime point would invariably indicate an arrow of time from past to future, though on a quantum scale it is not a linear flow but a closed loop, a fact that can be examined through future observations.

  10. 76 FR 7707 - Fludioxonil; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2011-02-11

    ... fungicide, such as fludioxonil, to address this issue, the future viability of the pineapple industry in... Departure/Levels of Concern Once a pesticide's toxicological profile is determined, EPA identifies... incidental oral exposure. Further information regarding EPA standard assumptions and generic inputs for...

  11. Detection of interference phase by digital computation of quadrature signals in homodyne laser interferometry

    Czech Academy of Sciences Publication Activity Database

    Řeřucha, Šimon; Buchta, Zdeněk; Šarbort, Martin; Lazar, Josef; Číp, Ondřej

    2012-01-01

    Roč. 12, č. 10 (2012), s. 14095-14112 ISSN 1424-8220 R&D Projects: GA ČR GAP102/10/1813; GA MŠk ED0017/01/01; GA MPO FR-TI2/705; GA MPO FR-TI1/241; GA MŠk EE2.3.30.0054 Institutional support: RVO:68081731 Keywords : digital signal processing * homodyne detection * laser interferometry * optical metrology Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.953, year: 2012

  12. Antimutagenic and antigenotoxic effects of vegetable matrices on the activity of pesticides.

    Science.gov (United States)

    Isidori, M; Caterino, E; Criscuolo, E; Fatigati, V; Liguori, G; Parrella, A

    2009-07-01

    Two in vitro tests, one to detect bacterial mutagenicity (Ames test) on Salmonella typhimurium TA98, TA100, and TA1535 and the other the primary DNA damage (SOS Chromotest) on Escherichia coli PQ37, were applied to determine the overall genotoxic activity of 12 pesticides (azinphos methyl, chlorothalonil, chlorphyriphos ethyl, chlorphyriphos methyl, lambda-cyhalothrin, cypermethrin, cyprodinil, fenazaquin, fludioxonil, indoxacarb, iprodione and penconazol). These were detected by gas chromatography (GC) analysis with electron capture (ECD) and nitrogen phosphorus detection (NPD) in 18 samples of vegetables. Some extracts of vegetables, found positive for pesticides with GC, were subjected to the Ames test and SOS Chromotest to evaluate the possible antimutagenic and/or antigenotoxic effects of vegetable matrices. The same bioassays were also performed on the mixtures of pesticides found in these samples to evaluate whether interactions could occur between pesticides and be responsible for the possible antimutagenic and/or antigenotoxic effects of the contaminated matrices. Experiments were also carried out to compare the results found for contaminated vegetables with their content of antioxidant components. Significant differences in mutagenicity and genotoxicity were found among the pesticides selected for this study. Of the 12 pesticides tested, only azinphos methyl, cyprodinil, fludioxonil and iprodione were found to be positive for both S. typhimurium and E. coli. No mutagenic/genotoxic activity was found in the extracts of vegetables contaminated by pesticides. S. typhimurium TA1535 showed a strong positive mutagenic effect for the mixtures of pesticides while they were not able to induce the SOS system. The data concerning the content of polyphenols and the total reducing activity of the contaminated vegetables indicated high amounts of antioxidants that could explain the inhibitory effect on the activity of pesticides shown by vegetables.

  13. Pesticides and children

    International Nuclear Information System (INIS)

    Garry, Vincent F.

    2004-01-01

    Prevention and control of damage to health, crops, and property by insects, fungi, and noxious weeds are the major goals of pesticide applications. As with use of any biologically active agent, pesticides have unwanted side-effects. In this review, we will examine the thesis that adverse pesticide effects are more likely to occur in children who are at special developmental and behavioral risk. Children's exposures to pesticides in the rural and urban settings and differences in their exposure patterns are discussed. The relative frequency of pesticide poisoning in children is examined. In this connection, most reported acute pesticide poisonings occur in children younger than age 5. The possible epidemiological relationships between parental pesticide use or exposure and the risk of adverse reproductive outcomes and childhood cancer are discussed. The level of consensus among these studies is examined. Current concerns regarding neurobehavioral toxicity and endocrine disruption in juxtaposition to the relative paucity of toxicant mechanism-based studies of children are explored

  14. Pyrethroid pesticide-induced alterations in dopamine transporter function

    International Nuclear Information System (INIS)

    Elwan, Mohamed A.; Richardson, Jason R.; Guillot, Thomas S.; Caudle, W. Michael; Miller, Gary W.

    2006-01-01

    Parkinson's disease (PD) is a progressive neurodegenerative disease affecting the nigrostriatal dopaminergic pathway. Several epidemiological studies have demonstrated an association between pesticide exposure and the incidence of PD. Studies from our laboratory and others have demonstrated that certain pesticides increase levels of the dopamine transporter (DAT), an integral component of dopaminergic neurotransmission and a gateway for dopaminergic neurotoxins. Here, we report that repeated exposure (3 injections over 2 weeks) of mice to two commonly used pyrethroid pesticides, deltamethrin (3 mg/kg) and permethrin (0.8 mg/kg), increases DAT-mediated dopamine uptake by 31 and 28%, respectively. Using cells stably expressing DAT, we determined that exposure (10 min) to deltamethrin and permethrin (1 nM-100 μM) had no effect on DAT-mediated dopamine uptake. Extending exposures to both pesticides for 30 min (10 μM) or 24 h (1, 5, and 10 μM) resulted in significant decrease in dopamine uptake. This reduction was not the result of competitive inhibition, loss of DAT protein, or cytotoxicity. However, there was an increase in DNA fragmentation, an index of apoptosis, in cells exhibiting reduced uptake at 30 min and 24 h. These data suggest that up-regulation of DAT by in vivo pyrethroid exposure is an indirect effect and that longer-term exposure of cells results in apoptosis. Since DAT can greatly affect the vulnerability of dopamine neurons to neurotoxicants, up-regulation of DAT by deltamethrin and permethrin may increase the susceptibility of dopamine neurons to toxic insult, which may provide insight into the association between pesticide exposure and PD

  15. Acute pesticide poisoning and pesticide registration in Central America

    International Nuclear Information System (INIS)

    Wesseling, Catharina; Corriols, Marianela; Bravo, Viria

    2005-01-01

    The International Code of Conduct on the Distribution and Use of Pesticides of the Food and Agriculture Organization (FAO) of the United Nations has been for 20 years the most acknowledged international initiative for reducing negative impact from pesticide use in developing countries. We analyzed pesticide use and poisoning in Central America, particularly in Costa Rica and Nicaragua, and evaluated whether registration decisions are based on such data, in accordance with the FAO Code. Extensive use of very hazardous pesticides continues in Central America and so do poisonings with organophosphates, carbamates, endosulfan and paraquat as the main causative agents. Central American governments do not carry out or commission scientific risk assessments. Instead, guidelines from international agencies are followed for risk management through the registration process. Documentation of pesticide poisonings during several decades never induced any decision to ban or restrict a pesticide. However, based on the official surveillance systems, in 2000, the ministers of health of the seven Central American countries agreed to ban or restrict twelve of these pesticides. Now, almost 4 years later, restrictions have been implemented in El Salvador and in Nicaragua public debate is ongoing. Chemical and agricultural industries do not withdraw problematic pesticides voluntarily. In conclusion, the registration processes in Central America do not comply satisfactorily with the FAO Code. However, international regulatory guidelines are important in developing countries, and international agencies should strongly extend its scope and influence, limiting industry involvement. Profound changes in international and national agricultural policies, steering towards sustainable agriculture based on non-chemical pest management, are the only way to reduce poisonings

  16. Bianchi type-I universe in f(R, T) modified gravity with quark matter and Λ

    Science.gov (United States)

    Ćaǧlar, Halife; Aygün, Sezgin

    2017-02-01

    In this study, we investigate homogeneous and anisotropic Bianchi type I universe in the presence of quark matter source in f(R, T) gravity (Harko et al. in Phys. Rev. D 84:024020, 2011) with cosmological constant Λ (where R is the Ricci scalar and T is the trace of the energy momentum tensor). For this aim we have used the anisotropy feature of Bianchi type I universe and equation of states (EoS) of quark matter. We explore the exact solution f(R,T)=R+2f(T) model for Bianchi type I universe model. When t→∞, we get very small cosmological constant value, this result agrees with recent observations.

  17. Environmental exposure to pesticides and respiratory health

    Directory of Open Access Journals (Sweden)

    Ali Mamane

    2015-09-01

    Full Text Available Respiratory effects of environmental exposure to pesticides are debated. Here we aimed to review epidemiological studies published up until 2013, using the PubMed database. 20 studies dealing with respiratory health and non-occupational pesticide exposure were identified, 14 carried out on children and six on adults. In four out of nine studies in children with biological measurements, mothers' dichlorodiphenyldichloroethylene (DDE blood levels during pregnancy were associated with asthma and wheezing in young children. An association was also found between permethrin in indoor air during pregnancy and wheezing in children. A significant association between asthma and DDE measured in children's blood (aged 7–10 years was observed in one study. However, in three studies, no association was found between asthma or respiratory infections in children and pesticide levels in breast milk and/or infant blood. Lastly, in three out of four studies where post-natal pesticide exposure of children was assessed by parental questionnaire an association with respiratory symptoms was found. Results of the fewer studies on pesticide environmental exposure and respiratory health of adults were much less conclusive: indeed, the associations observed were weak and often not significant. In conclusion, further studies are needed to confirm whether there is a respiratory risk associated with environmental exposure to pesticides.

  18. Mechanochemical synthesis of magnetically hard anisotropic RFe{sub 10}Si{sub 2} powders with R representing combinations of Sm, Ce and Zr

    Energy Technology Data Exchange (ETDEWEB)

    Gabay, A.M., E-mail: gabay@udel.edu; Hadjipanayis, G.C.

    2017-01-15

    Alloy synthesis consisting of mechanical activation followed by annealing was explored as a method of manufacturing medium-grade permanent magnet materials with a reduced content of the critical rare earth elements. Four R{sub x}Fe{sub 10}Si{sub 2} alloys with R=Sm, Sm{sub 0.7}Zr{sub 0.3}, Sm{sub 0.3}Ce{sub 0.3}Zr{sub 0.4} and Ce{sub 0.6}Zr{sub 0.4} (nominal compositions) were prepared from mixtures of Sm{sub 2}O{sub 3}, CeO{sub 2}, ZrO{sub 2}, Fe{sub 2}O{sub 3} and Si powders in the presence of a reducing agent Ca and a CaO dispersant. The collected alloy particles typically consisted of few joined submicron crystals. For R=Sm, X-ray diffraction analysis reveals a significant amount of the unwanted Th{sub 2}Zn{sub 17}-type compound forming alongside the desired ThMn{sub 12}-type 1:12 compound. A more pure 1:12 phase could be obtained for R=Ce{sub 0.6}Zr{sub 0.4}, but it exhibited a room-temperature coercivity of less than 1 kOe. The most pure 1:12 phase and the highest values of the coercivity (10.8 kOe) and calculated maximum energy product (13.8 MGOe) were obtained for R=Sm{sub 0.7}Zr{sub 0.3} processed at 1150 °C. The calculated maximum energy products of the Sm{sub 0.3}Ce{sub 0.3}Zr{sub 0.4}Fe{sub 10}Si{sub 2} particles, with half of their rare earths constituents represented by the relatively abundant Ce, was 10.1 MGOe. - Highlights: • 30% Zr substitution for Sm improves prospects of the alloys as permanent magnets. • Pure ThMn{sub 12}-type structure could only be obtained in the Zr-substituted alloys. • Obtained powders exhibit better properties than nanocrystalline Sm(Fe,M){sub 12} alloys. • If fully dense, alloy containing only 2.3 at% Sm would energy product of 10 MGOe.

  19. 75 FR 60452 - Notice of Filing of Several Pesticide Petitions for Residues of Pesticide Chemicals in or on...

    Science.gov (United States)

    2010-09-30

    ... pesticide petition summary. You may also reach each contact person by mail at Biopesticides and Pollution.... Dated: September 23, 2010. W. Michael McDavit, Acting Director, Biopesticides and Pollution Prevention...

  20. 75 FR 32766 - Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-06-09

    ... to Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... or Mosquitoes, LLC., to voluntarily cancel the pesticide registration for the product, Biter Fighter... registrant requested a waiver of the 180-day comment period, orders will be issued canceling this...

  1. 75 FR 70256 - Tralomethrin; Notice of Receipt of Request To Voluntarily Cancel Pesticide Registrations

    Science.gov (United States)

    2010-11-17

    ... of Request To Voluntarily Cancel Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... voluntarily cancel their registrations of products containing the pesticide tralomethrin. The request would... will cancel the sole technical product registration for tralomethrin. EPA intends to grant this request...

  2. 75 FR 5318 - Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-02-02

    ... to Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... voluntarily cancel certain pesticide registrations. DATES: Unless a request is withdrawn by or March 4, 2010... will be issued canceling these registrations. The Agency will consider withdrawal requests postmarked...

  3. Pesticides: chemicals for survival

    International Nuclear Information System (INIS)

    Lindquist, D.A.

    1981-01-01

    Pesticides are chemicals used to control pests such as insects, weeds, plant diseases, nematodes, and rodents. The increased use of pesticides since 1945 has greatly aided the increase in crop production, protected livestock from diseases such as trypanosomiasis, protected man from diseases such as malaria and filarisis, decreased losses of stored grain, and has generally improved man's welfare. Despite the enormous benefits derived from pesticides these chemicals are not problem-free. Many pesticides are toxic to living organisms and interfere with specific biochemical systems. To measure the very small quantities of a pesticide radiolabelled chemicals are frequently essential, particularly to measure changes in the chemical structure of the pesticide, movement of the pesticide in soil, plants, or animals, amounts of pesticide going through various steps in food processing, etc. The use of radiolabelled pesticides is shortly shown for metabolism of the pesticide in crop species, metabolism in ruminant, in chickens and eggs, in soil, and possibly leaching and sorption in soil, hydrolysis, bio-concentration, microbial and photodegradation, and toxicity studies

  4. Study on the interaction of catalase with pesticides by flow injection chemiluminescence and molecular docking.

    Science.gov (United States)

    Tan, Xijuan; Wang, Zhuming; Chen, Donghua; Luo, Kai; Xiong, Xunyu; Song, Zhenghua

    2014-08-01

    The interaction mechanisms of catalase (CAT) with pesticides (including organophosphates: disulfoton, isofenphos-methyl, malathion, isocarbophos, dimethoate, dipterex, methamidophos and acephate; carbamates: carbaryl and methomyl; pyrethroids: fenvalerate and deltamethrin) were first investigated by flow injection (FI) chemiluminescence (CL) analysis and molecular docking. By homemade FI-CL model of lg[(I0-I)/I]=lgK+nlg[D], it was found that the binding processes of pesticides to CAT were spontaneous with the apparent binding constants K of 10(3)-10(5) L mol(-1) and the numbers of binding sites about 1.0. The binding abilities of pesticides to CAT followed the order: fenvalerate>deltamethrin>disulfoton>isofenphos-methyl>carbaryl>malathion>isocarbophos>dimethoate>dipterex>acephate>methomyl>methamidophos, which was generally similar to the order of determination sensitivity of pesticides. The thermodynamic parameters revealed that CAT bound with hydrophobic pesticides by hydrophobic interaction force, and with hydrophilic pesticides by hydrogen bond and van der Waals force. The pesticides to CAT molecular docking study showed that pesticides could enter into the cavity locating among the four subdomains of CAT, giving the specific amino acid residues and hydrogen bonds involved in CAT-pesticides interaction. It was also found that the lgK values of pesticides to CAT increased regularly with increasing lgP, Mr, MR and MV, suggesting that the hydrophobicity and steric property of pesticide played essential roles in its binding to CAT. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Distribution and Predictors of Pesticides in the Umbilical Cord Blood of Chinese Newborns

    Directory of Open Access Journals (Sweden)

    Monica K. Silver

    2015-12-01

    Full Text Available Rates of pesticide use in Chinese agriculture are five times greater than the global average, leading to high exposure via the diet. Many are neurotoxic, making prenatal pesticide exposure a concern. Previous studies of prenatal exposure in China focused almost entirely on organochlorines. Here the study goals were to characterize the exposure of Chinese newborns to all classes of pesticides and identify predictors of those exposures. Eighty-four pesticides and 12 metabolites were measured in the umbilical cord plasma of 336 infants. Composite variables were created for totals detected overall and by class. Individual pesticides were analyzed as dichotomous or continuous, based on detection rates. Relationships between demographic characteristics and pesticides were evaluated using generalized linear regression. Seventy-five pesticides were detected. The mean number of detects per sample was 15.3. Increased pesticide detects were found in the cord blood of infants born in the summer (β = 2.2, p = 0.01, particularly in July (β = 4.0, p = 0.03. Similar trends were observed for individual insecticide classes. Thus, a summer birth was the strongest predictor of pesticide evidence in cord blood. Associations were more striking for overall pesticide exposure than for individual pesticides, highlighting the importance of considering exposure to mixtures of pesticides, rather than individual agents or classes.

  6. 76 FR 11456 - Pesticide Reregistration Performance Measures and Goals

    Science.gov (United States)

    2011-03-02

    ... be reregistered. A variety of outcomes are possible for pesticide products completing this final... or reviewed by the Agency. The universe of products in product reregistration has increased in some years and decreased in other years. Generally, an increase resulted from products associated with the...

  7. 78 FR 29049 - Streptomycin; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2013-05-17

    ... determine whether this document applies to them. Potentially affected entities may include: Crop production (NAICS code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311). Pesticide....40 ppm. Streptomycin is an antibiotic of the aminoglycoside class and is produced by the bacteria...

  8. Mycotoxins, pesticides and toxic metals in commercial spices and herbs.

    Science.gov (United States)

    Reinholds, Ingars; Pugajeva, Iveta; Bavrins, Konstantins; Kuckovska, Galina; Bartkevics, Vadims

    2017-03-01

    A total of 300 samples representing six condiments (black pepper, basil, oregano, nutmeg, paprika, and thyme) were analysed for 11 mycotoxins, 134 pesticides and 4 heavy metals by ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry and inductively coupled plasma mass spectrometry. Mycotoxins were detected in 4%, 10% and 30% of all nutmeg, basil and thyme samples, respectively. The residues of 24 pesticides were detected in 59% of the analysed condiments. The maximum residue levels of pesticides were exceeded in 10% of oregano and 46% of thyme samples. A risk assessment of heavy metals was performed, indicating daily intake levels far below the tolerable intake levels.

  9. From my Home: Dvarionas: Elegie / Rob Cowan

    Index Scriptorium Estoniae

    Cowan, Rob

    1997-01-01

    Uuest heliplaadist "From my Home: Dvarionas: Elegie; Pärt: Fratres; Barkauskas: Partita; Vasks: Musica Dolorosa; Pelecis: Concerto for Violin, Piano and String Orchestra, "Neverthless"; Plakidis: Two Grasshopper Dances; Tüür: Conversio. Deutsche Kammerphilharmonie. Teldec 0630-14654-2 (79 minutes:DDD)

  10. Changes in bacterial diversity and community structure following pesticides addition to soil estimated by cultivation technique.

    Science.gov (United States)

    Cycoń, Mariusz; Piotrowska-Seget, Zofia

    2009-07-01

    An experiment was conducted under laboratory conditions to investigate the effect of increasing concentrations of fenitrothion (2, 10 and 200 mg a.i./kg soil), diuron (1.5, 7.5 and 150 mg a.i./kg soil) and thiram (3.5, 17.5 and 350 mg a.i./kg soil) on soil respiration, bacterial counts and changes in culturable fraction of soil bacteria. To ascertain these changes, the community structure, bacterial biodiversity and process of colony formation, based on the r/K strategy concept, EP- and CD-indices and the FOR model, respectively, were determined. The results showed that the measured parameters were generally unaffected by the lowest dosages of pesticides, corresponding to the recommended field rates. The highest dosages of fenitrothion and thiram suppressed the peak SIR by 15-70% and 20-80%, respectively, while diuron increased respiration rate by 17-25% during the 28-day experiment. Also, the total numbers of bacteria increased in pesticide-treated soils. However, the reverse effect on day 1 and, in addition, in case of the highest dosages of insecticide on days 14 and 28, was observed. Analysis of the community structure revealed that in all soil treatments bacterial communities were generally dominated by K-strategists. Moreover, differences in the distribution of individual bacteria classes and the gradual domination of bacteria populations belonging to r-strategists during the experiment, as compared to control, was observed. However, on day 1, at the highest pesticide dosages, fast growing bacteria constituted only 1-10% of the total colonies number during 48 h of plate incubation, whereas in remaining samples they reached from 20 to 40% of total cfu. This effect, in case of fenitrothion, lasted till the end of the experiment. At the highest dosages of fenitrothion, diuron and at all dosages of thiram the decrease of biodiversity, as indicated by EP- and CD-indices on day 1, was found. At the next sampling time, no significant retarding or stimulating effect

  11. Pesticide Use and Asthma in Alberta Grain Farmers

    Directory of Open Access Journals (Sweden)

    Nicola Cherry

    2018-03-01

    Full Text Available A study of the respiratory health of grain farmers in Alberta, Canada was carried out in March 2002. Two populations were identified: members, in 1983, of a province-wide farm organisation, and grain farmers registered with the provincial agriculture department. A telephone interview addressed pesticide use (using pre-circulated trade names, chronic disease and respiratory symptoms. Pesticide ingredients were identified from provincial crop protection guides. Total years of use were calculated for seven chemical groups. Consent for linkage to administrative health records was obtained in 2009. A likelihood score (Lscore is computed, relating symptoms to asthma diagnosis. Self-reported asthma and the Lscore are examined against duration of pesticide exposures. Of the 10,767 farmers listed, 2426 were still living, had farmed grain and were interviewed; 1371 were re-contacted and matched to health records. After allowance for confounders, years of exposure to phenoxy compounds are related to self-reported asthma and Lscore. Compared to no exposure, the adjusted odds ratios (95% Confidence Intervals for self-reported asthma for short, medium and long exposure to phenoxy compounds are 1.29 (0.66–2.52, 2.52 (1.25–5.09, and 3.18 (1.54–6.58, and for Lscore are 1.19 (0.91–1.55, 1.50 (1.13–1.99, and 1.58 (1.18–2.12. We conclude that lifetime exposure to phenoxy herbicides is associated with an increased risk of asthma.

  12. 10 CFR 602.12 - Cost sharing.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Cost sharing. 602.12 Section 602.12 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.12 Cost sharing. Cost sharing is not required, nor will it be considered, as a criterion in...

  13. Irradiation degradation of carbamate and organophosphorous pesticides in Chinese herbal medicines

    International Nuclear Information System (INIS)

    Chen Qiyong; Chang Chunyan; Xiao Yabing; Wu Ruoxin

    2013-01-01

    In order to put forward new method and basis to remove pesticide residues in Chinese herbs, the influence factors such as irradiation doses and water content of electron beam irradiation on degradation efficiency of carbamate and organophosphorous pesticides in ginseng are investigated. Additionally, the irradiation degradation of two pesticides treated with the same dose in several traditional Chinese herbal medicines like Baifuling is also studied. The irradiation can effectively degrade these pesticide residues in herbal medicines; the efficiency of lower doses are inferior to higher doses. The degradation rate rises when dose increases, and varies among 4 ∼ 10 kGy in different Chinese herbal medicines. The degradation efficiency of organophosphorous pesticides is better than those of carbamate pesticides. (authors)

  14. 10 + 10 + 10 = 24?

    DEFF Research Database (Denmark)

    Andersen, Johannes

    2014-01-01

    efter en 10+10+10 timers model. Ifølge lektor og samfundsforsker Johannes Andersen ved Institut for statskundskab på Aalborg Universitet, er antallet af stress ramte danskere steget fra 5 procent i 1989 til mere end 12 procent i 2010. Således tyder noget på, at danskerne ikke får den fornødne hvile....

  15. 78 FR 15949 - Notice of Receipt of Request To Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2013-03-13

    ... Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA). ACTION... is issuing a notice of receipt of requests by a registrant to voluntarily cancel certain pesticide... in this notice will be permitted after the registration has been canceled only if such sale...

  16. 76 FR 47579 - Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2011-08-05

    ... To Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... voluntarily cancel certain pesticide registrations. EPA intends to grant these requests at the close of the... will be permitted after the registrations have been cancelled only if such sale, distribution, or use...

  17. Monitoring of Some Pesticides Residue in Consumed tea in Tehran Market

    Directory of Open Access Journals (Sweden)

    Maryam Amirahmadi

    2013-01-01

    Full Text Available Tea is an agricultural product of the leaves, leaf buds, and internodes of various cultivars and sub-varieties of the Camellia sinensis plant, processed and vulcanized using various methods. Tea is a main beverage in Iranian food basket so should be free from toxic elements such as pesticides residue. There is no data bank on the residue of pesticides in the consumed black tea in Iran. The present study is the first attempt for monitoring of 25 pesticide residues from different chemical groups in tea samples obtained from local markets in Tehran, I.R. Iran during the period 2011. A reliable and accurate method based on spiked calibration curve and QuEChERS sample preparation was developed for determination of pesticide residues in tea by gas chromatography--mass spectrometry (GC/MS. The using of spiked calibration standards for constructing the calibration curve substantially reduced adverse matrix-related effects and negative recovery affected by GCB on pesticides. The recovery of pesticides at 3 concentration levels (n = 3 was in range of 81.4 - 99.4%. The method was proved to be repeatable with RSDr lower than 20%. The limits of quantification for all pesticides were <=20 ng/g. 53 samples from 17 imported and manufactured brand were analyzed. Detectable pesticides residues were found in 28.3% (15 samples of the samples. All of the positive samples were contaminated with unregulated pesticides (Endosulfan Sulfate or Bifenthrin which are established by ISIRI. None of the samples had contamination higher than maximum residue limit set by EU and India.

  18. Monitoring of some pesticides residue in consumed tea in Tehran market

    Directory of Open Access Journals (Sweden)

    Hamedani Morteza Pirali

    2013-01-01

    Full Text Available Abstract Tea is an agricultural product of the leaves, leaf buds, and internodes of various cultivars and sub-varieties of the Camellia sinensis plant, processed and vulcanized using various methods. Tea is a main beverage in Iranian food basket so should be free from toxic elements such as pesticides residue. There is no data bank on the residue of pesticides in the consumed black tea in Iran. The present study is the first attempt for monitoring of 25 pesticide residues from different chemical groups in tea samples obtained from local markets in Tehran, I.R. Iran during the period 2011. A reliable and accurate method based on spiked calibration curve and QuEChERS sample preparation was developed for determination of pesticide residues in tea by gas chromatography–mass spectrometry (GC/MS. The using of spiked calibration standards for constructing the calibration curve substantially reduced adverse matrix-related effects and negative recovery affected by GCB on pesticides. The recovery of pesticides at 3 concentration levels (n = 3 was in range of 81.4 - 99.4%. The method was proved to be repeatable with RSDr lower than 20%. The limits of quantification for all pesticides were ≤20 ng/g. 53 samples from 17 imported and manufactured brand were analyzed. Detectable pesticides residues were found in 28.3% (15 samples of the samples. All of the positive samples were contaminated with unregulated pesticides (Endosulfan Sulfate or Bifenthrin which are established by ISIRI. None of the samples had contamination higher than maximum residue limit set by EU and India.

  19. Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma

    Science.gov (United States)

    Araya, Paula; Nuñez, Nicolás Gonzalo; Mena, Hebe Agustina; Bocco, José Luis; Negrotto, Soledad; Maccioni, Mariana

    2017-01-01

    The mechanisms that link inflammatory responses to cancer development remain a subject of intense investigation, emphasizing the need to better understand the cellular and molecular pathways that create a tumor promoting microenvironment. The myeloid differentiation primary response protein MyD88 acts as a main adaptor molecule for the signaling cascades initiated from Toll-like receptors (TLRs) and the interleukin 1 receptor (IL-1R). MyD88 has been shown to contribute to tumorigenesis in many inflammation-associated cancer models. In this study, we sought to better define the role of MyD88 in neoplastic cells using a murine melanoma model. Herein, we have demonstrated that MyD88 expression is required to maintain the angiogenic switch that supports B16 melanoma growth. By knocking down MyD88 we reduced TLR-mediated NF-κB activation with no evident effects over cell proliferation and survival. In addition, MyD88 downregulation was associated with a decrease of HIF1α levels and its target gene VEGF, in correlation with an impaired capability to induce capillary sprouting and tube formation of endothelial cells. Melanomas developed from cells lacking MyD88 showed an enhanced secretion of chemoattractant ligands such as CCL2, CXCL10 and CXCL1 and have an improved infiltration of macrophages to the tumor site. Our results imply that cell-autonomous signaling through MyD88 is required to sustain tumor growth and underscore its function as an important positive modulator of tumor angiogenesis. PMID:28662055

  20. Omsättning, rörelseresultat och kapitalstruktur – Påverkas företags kapitalstruktur av förändringar i dess omsättning eller rörelseresultat?

    OpenAIRE

    Lisstorp, Mattias; Steinberger, Paul

    2012-01-01

    Syftet med uppsatsen är att undersöka hur omsättning och rörelseresultat har samband med företagets kapitalstruktur. Resultaten jämförs med befintlig teori för att verifiera de teoretiska ansatserna. Regressionsanalys av tidsserier för 32 svenska börsnoterade företag med mer än 20 miljarder svenska kronor i omsättning 2010 har använts vid den här undersökningen. Data från åren 2004 till 2010 till varje företag är tagen från databasen ”Affärsdata” och undersöks genom regressionsanalys. Först u...

  1. Models of collapsing and expanding anisotropic gravitating source in f(R, T) theory of gravity

    Energy Technology Data Exchange (ETDEWEB)

    Abbas, G. [The Islamia University of Bahawalpur, Department of Mathematics, Bahawalpur (Pakistan); Ahmed, Riaz [The Islamia University of Bahawalpur, Department of Mathematics, Bahawalpur (Pakistan); University of the Central Punjab, Department of Mathematics, Lahore (Pakistan)

    2017-07-15

    In this paper, we have formulated the exact solutions of the non-static anisotropic gravitating source in f(R, T) gravity which may lead to expansion and collapse. By assuming there to be no thermal conduction in gravitating source, we have determined parametric solutions in f(R, T) gravity with a non-static spherical geometry filled using an anisotropic fluid. We have examined the ranges of the parameters for which the expansion scalar becomes negative and positive, leading to collapse and expansion, respectively. Further, using the definition of the mass function, the conditions for the trapped surface have been explored, and it has been investigated that there exists a single horizon in this case. The impact of the coupling parameter λ has been discussed in detail in both cases. For the various values of the coupling parameter λ, we have plotted the energy density, anisotropic pressure and anisotropy parameter in the cases of collapse and expansion. The physical significance of the graphs has been explained in detail. (orig.)

  2. Development and validation of a simple GC-MS method for the simultaneous determination of 11 anticholinesterase pesticides in blood--clinical and forensic toxicology applications.

    Science.gov (United States)

    Papoutsis, Ioannis; Mendonis, Marcela; Nikolaou, Panagiota; Athanaselis, Sotirios; Pistos, Constantinos; Maravelias, Constantinos; Spiliopoulou, Chara

    2012-05-01

    Anticholinesterase pesticides are widely used, and as a result they are involved in numerous acute and even fatal poisonings. The aim of this study was the development, optimization, and validation of a simple, rapid, specific, and sensitive gas chromatography-mass spectrometry method for the determination of 11 anticholinesterase pesticides (aldicarb, azinphos methyl, carbofuran, chlorpyrifos, dialifos, diazinon, malathion, methamidophos, methidathion, methomyl, and terbufos) in blood. Only 500 μL of blood was used, and the recoveries after liquid-liquid extraction (toluene/chloroform, 4:1, v/v) were more than 65.6%. The calibration curves were linear (R(2) ≥ 0.996). Limit of detections and limit of quantifications were found to be between 1.00-10.0 and 3.00-30.0 μg/L, respectively. Accuracy expressed as the %E(r) was found to be between -11.0 and 7.8%. Precision expressed as the percent relative standard deviation was found to be forensic and clinical cases of accidental or suicidal poisoning with these pesticides. © 2011 American Academy of Forensic Sciences.

  3. Pesticide Residues in Commercial Lettuce, Onion, and Potato Samples From Bolivia—A Threat to Public Health?

    DEFF Research Database (Denmark)

    Skovgaard, Marlene; Renjel, Susana; Jensen, Olaf Chresten

    2017-01-01

    Bolivia does not have a surveillance program for pesticide residues in food. The few published studies have suggested that pesticide contamination in food may present a public health problem. Data are lacking for all foods except tomatoes and breast milk. In this study 10 potato, 10 onion, and 10...... or together would lead to exposures that exceeded the acceptable daily intake or the acute reference dose. To protect consumers from pesticide poisonings and chronic effects, the development of measures for prevention, control, and monitoring of food contamination by pesticides in Bolivia is suggested....

  4. MyShake - Smartphone seismic network powered by citizen scientists

    Science.gov (United States)

    Kong, Q.; Allen, R. M.; Schreier, L.; Strauss, J. A.

    2017-12-01

    MyShake is a global smartphone seismic network that harnesses the power of crowdsourcing. It is driven by the citizen scientists that run MyShake on their personal smartphones. It has two components: an android application running on the smartphones to detect earthquake-like motion, and a network detection algorithm to aggregate results from multiple smartphones to confirm when an earthquake occurs. The MyShake application was released to the public on Feb 12th 2016. Within the first year, more than 250,000 people downloaded MyShake app around the world. There are more than 500 earthquakes recorded by the smartphones in this period, including events in Chile, Argentina, Mexico, Morocco, Greece, Nepal, New Zealand, Taiwan, Japan, and across North America. Currently, we are working on earthquake early warning with MyShake network and the shaking data provided by MyShake is a unique dataset that can be used for the research community.

  5. Thermodynamic geometry of black holes in f(R) gravity

    International Nuclear Information System (INIS)

    Soroushfar, Saheb; Saffari, Reza; Kamvar, Negin

    2016-01-01

    In this paper, we consider three types (static, static charged, and rotating charged) of black holes in f(R) gravity. We study the thermodynamical behavior, stability conditions, and phase transition of these black holes. It is shown that the number and type of phase transition points are related to different parameters, which shows the dependency of the stability conditions to these parameters. Also, we extend our study to different thermodynamic geometry methods (Ruppeiner, Weinhold, and GTD). Next, we investigate the compatibility of curvature scalar of geothermodynamic methods with phase transition points of the above black holes. In addition, we point out the effect of different values of the spacetime parameters on the stability conditions of mentioned black holes. (orig.)

  6. Cusp singularities in f(R) gravity: pros and cons

    International Nuclear Information System (INIS)

    Chen, Pisin; Yeom, Dong-han

    2015-01-01

    We investigate cusp singularities in f(R) gravity, especially for Starobinsky and Hu-Sawicki dark energy models. We illustrate that, by using double-null numerical simulations, a cusp singularity can be triggered by gravitational collapses. This singularity can be cured by adding a quadratic term, but this causes a Ricci scalar bump that can be observed by an observer outside the event horizon. Comparing with cosmological parameters, it seems that it would be difficult to see super-Planckian effects by astrophysical experiments. On the other hand, at once there exists a cusp singularity, it can be a mechanism to realize a horizon scale curvature singularity that can be interpreted by a firewall

  7. Binderless Zeolite Coatings on Macroporous α-SiC Foams

    Czech Academy of Sciences Publication Activity Database

    Losch, P.; Boltz, M.; Soukup, Karel; Song, I.-H.; Yun, H.S.; Louis, B.

    2014-01-01

    Roč. 188, APR (2014), s. 99-107 ISSN 1387-1811 R&D Projects: GA MŠk 7AMB12FR029 Grant - others:ANR(FR) ANR-10-JCJC-0703; ANR(FR) Barrande 26551RE Institutional support: RVO:67985858 Keywords : ZSM-5 * alalcime * self-recrystallization Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 3.453, year: 2014

  8. The miR-10 microRNA precursor family

    DEFF Research Database (Denmark)

    Tehler, Disa; Høyland-Kroghsbo, Nina Molin; Lund, Anders H

    2011-01-01

    The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox...... gene developmental regulators. Here, we review the current knowledge of the evolution, physiological function and involvement in cancer of this family of microRNAs....

  9. Occurrence of pesticides in surface water and sediments from three central California coastal watersheds, 2008-2009

    Science.gov (United States)

    Smalling, Kelly L.; Orlando, James L.

    2011-01-01

    Water and sediment (bed and suspended) were collected from January 2008 through October 2009 from 12 sites in 3 of the largest watersheds along California's Central Coast (Pajaro, Salinas, and Santa Maria Rivers) and analyzed for a suite of pesticides by the U.S. Geological Survey. Water samples were collected in each watershed from the estuaries and major tributaries during 4 storm events and 11 dry season sampling events in 2008 and 2009. Bed sediments were collected from depositional zones at the tributary sampling sites three times over the course of the study. Suspended sediment samples were collected from the major tributaries during the four storm events and in the tributaries and estuaries during three dry season sampling events in 2009. Water samples were analyzed for 68 pesticides using gas chromatography/mass spectrometry. A total of 38 pesticides were detected in 144 water samples, and 13 pesticides were detected in more than half the samples collected over the course of the study. Dissolved pesticide concentrations ranged from below their method detection limits to 36,000 nanograms per liter (boscalid). The most frequently detected pesticides in water from all the watersheds were azoxystrobin, boscalid, chlorpyrifos, DCPA, diazinon, oxyfluorfen, prometryn, and propyzamide, which were found in more than 80 percent of the samples. On average, detection frequencies and concentrations were higher in samples collected during winter storm events compared to the summer dry season. With the exception of the fungicide, myclobutanil, the Santa Maria estuary watershed exhibited higher pesticide detection frequencies than the Pajaro and Salinas watersheds. Bed and suspended sediment samples were analyzed for 55 pesticides using accelerated solvent extraction, gel permeation chromatography for sulfur removal, and carbon/alumina stacked solid-phase extraction cartridges to remove interfering sediment matrices. In bed sediment samples, 17 pesticides were detected

  10. Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src.

    Directory of Open Access Journals (Sweden)

    Mian M K Shahzad

    Full Text Available The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA. MTT assays and QCM™ chemotaxis 96-wells were used to test the effect of t10,c12 CLA on the proliferation and migration and invasion of cancer cells. qPCR and Western Blotting were used to determine the expression of specific factors. RNA sequencing was conducted using the Illumina platform and apoptosis was measured using a flow cytometry assay. t10,c12 CLA (IC50, 7 μM inhibited proliferation of ovarian cancer cell lines SKOV-3 and A2780. c9,t11 CLA did not attenuate the proliferation of these cells. Transcription of 165 genes was significantly repressed and 28 genes were elevated. Genes related to ER stress, ATF4, CHOP, and GADD34 were overexpressed whereas EDEM2 and Hsp90, genes required for proteasomal degradation of misfolded proteins, were downregulated upon treatment. While apoptosis was not detected, t10,c12 CLA treatment led to 9-fold increase in autophagolysosomes and higher levels of LC3-II. G1 cell cycle arrest in treated cells was correlated with phosphorylation of GSK3β and loss of β-catenin. microRNA miR184 and miR215 were upregulated. miR184 likely contributed to G1 arrest by downregulating E2F1. miR215 upregulation was correlated with increased expression of p27/Kip-1. t10,c12 CLA-mediated inhibition of invasion and migration correlated with decreased expression of PTP1b and decreased Src activation by inhibiting phosphorylation at Tyr416. Due to its ability to inhibit proliferation and migration, t10,c12 CLA should be considered for treatment of ovarian cancer.

  11. Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src.

    Science.gov (United States)

    Shahzad, Mian M K; Felder, Mildred; Ludwig, Kai; Van Galder, Hannah R; Anderson, Matthew L; Kim, Jong; Cook, Mark E; Kapur, Arvinder K; Patankar, Manish S

    2018-01-01

    The goal of this study was to investigate the anti-cancer effects of Trans10,cis12 conjugated linoleic acid (t10,c12 CLA). MTT assays and QCM™ chemotaxis 96-wells were used to test the effect of t10,c12 CLA on the proliferation and migration and invasion of cancer cells. qPCR and Western Blotting were used to determine the expression of specific factors. RNA sequencing was conducted using the Illumina platform and apoptosis was measured using a flow cytometry assay. t10,c12 CLA (IC50, 7 μM) inhibited proliferation of ovarian cancer cell lines SKOV-3 and A2780. c9,t11 CLA did not attenuate the proliferation of these cells. Transcription of 165 genes was significantly repressed and 28 genes were elevated. Genes related to ER stress, ATF4, CHOP, and GADD34 were overexpressed whereas EDEM2 and Hsp90, genes required for proteasomal degradation of misfolded proteins, were downregulated upon treatment. While apoptosis was not detected, t10,c12 CLA treatment led to 9-fold increase in autophagolysosomes and higher levels of LC3-II. G1 cell cycle arrest in treated cells was correlated with phosphorylation of GSK3β and loss of β-catenin. microRNA miR184 and miR215 were upregulated. miR184 likely contributed to G1 arrest by downregulating E2F1. miR215 upregulation was correlated with increased expression of p27/Kip-1. t10,c12 CLA-mediated inhibition of invasion and migration correlated with decreased expression of PTP1b and decreased Src activation by inhibiting phosphorylation at Tyr416. Due to its ability to inhibit proliferation and migration, t10,c12 CLA should be considered for treatment of ovarian cancer.

  12. Association of Paraoxonase-1 Q192R (rs662 Single Nucleotide Variation with Cardiovascular Risk in Coffee Harvesters of Central Colombia

    Directory of Open Access Journals (Sweden)

    Fernando Siller-López

    2017-01-01

    Full Text Available Paraoxonase 1 (PON1, a high-density lipoprotein-associated antioxidant enzyme, hydrolyzes several organophosphate pesticides and oxidized lipids. The PON1 Q192R polymorphism affects the catalytic efficiency and is considered a risk factor for pesticide intoxication and cardiovascular disease (CVD but the association is not consistent between individuals or populations. We aimed to study the association of PON1 Q192R polymorphism with CVD risk in coffee harvesters of central Colombia. Demographics were collected from 205 subjects via standardized questionnaires. Lipid profiles and serum butyrylcholinesterase (BChE were measured by standard procedures. The calculated 10-year atherosclerotic CVD (ASCVD risk was used as the cardiovascular risk estimate. Q192R genotype was determined by real-time PCR. Prevalence of hypertension, hypercholesterolemia, and the 10-year ASCVD risk was 33%, 62%, and 22%, respectively. BChE levels were no indicative of recent pesticide exposure, although a positive correlation was observed with BChE and hypercholesterolemia. The Q192R genotype frequencies were 38% (QQ, 44% (QR, and 18% (RR. We found an association of the 192Q genotype with hypertension. The results of this study signal the importance to evaluate the influence and potential interactions of BChE and PON1 192Q allele with known genetic and environmental factors implicated in the pathogenesis of CVD.

  13. 41 CFR 304-3.12 - Must I receive advance approval from my agency before I perform travel paid by a non-Federal...

    Science.gov (United States)

    2010-07-01

    ... approval from my agency before I perform travel paid by a non-Federal source to attend a meeting? 304-3.12... agency before I perform travel paid by a non-Federal source to attend a meeting? Yes, you must receive advance approval from your agency before performing travel paid by a non-Federal source to attend a...

  14. The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.

    Directory of Open Access Journals (Sweden)

    Gaëlle Chognard

    Full Text Available IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23 receptors share a common subunit, it has been assumed that these receptors are co-expressed. Surprisingly, we find that the expression of each of these receptors is restricted to specific cell types, in both mouse and human. Indeed, although IL-12Rβ2 is expressed by NK cells and a subset of γδ T cells, the expression of IL-23R is restricted to specific T cell subsets, a small number of B cells and innate lymphoid cells. By exploiting an IL-12- and IL-23-dependent mouse model of innate inflammation, we demonstrate an intricate interplay between IL-12Rβ2 NK cells and IL-23R innate lymphoid cells with respectively dominant roles in the regulation of systemic versus local inflammatory responses. Together, these findings support an unforeseen lineage-specific dichotomy in the in vivo role of both the IL-12 and IL-23 pathways in pathological inflammatory states, which may allow more accurate dissection of the roles of these receptors in chronic inflammatory diseases in humans.

  15. 41 CFR 301-10.421 - How much will my agency reimburse me for a tip to a taxi, shuttle service, or courtesy...

    Science.gov (United States)

    2010-07-01

    ... reimburse me for a tip to a taxi, shuttle service, or courtesy transportation driver? 301-10.421 Section 301..., Shuttle Services, Or Other Courtesy Transportation § 301-10.421 How much will my agency reimburse me for a tip to a taxi, shuttle service, or courtesy transportation driver? An amount which your agency...

  16. Pattern of pesticide storage before pesticide self-poisoning in rural Sri Lanka

    DEFF Research Database (Denmark)

    Mohamed, Fahim; Manuweera, Gamini; Gunnell, David

    2009-01-01

    BACKGROUND: Deliberate self-poisoning with agricultural pesticides is the commonest means of suicide in rural Asia. It is mostly impulsive and facilitated by easy access to pesticides. The aim of this large observational study was to investigate the immediate source of pesticides used for self......-harm to help inform suicide prevention strategies such as reducing domestic access to pesticides. METHODS: The study was conducted in a district hospital serving an agricultural region of Sri Lanka. Patients who had self-poisoned with pesticides and were admitted to the adult medical wards were interviewed...... the particular pesticide for self-harm were its easy accessibility (n = 311, 46%) or its popularity as a suicide agent in their village (n = 290, 43%). CONCLUSION: Three quarters of people who ingested pesticides in acts of self-harm used products that were available within the home or in close proximity...

  17. Chronische Polyarthritis (Früharthritis

    Directory of Open Access Journals (Sweden)

    Machold K

    2005-01-01

    Full Text Available Die Akkumulation von Knorpel- und Knochenschäden, wie sie für chronisch-destruktive Arthritisformen typisch ist, kann durch frühzeitige Intervention mit wirksamen Medikamenten verzögert oder verhindert werden. Voraussetzung ist die rechtzeitige Übernahme der Betreuung gefährdeter Patienten durch einen in der speziellen rheumatologischen Diagnostik und Therapie bewanderten Arzt. Dieser muß das gesamte Repertoire der Arthritistherapie (Medikamente, ergotherapeutische und physiotherapeutische Maßnahmen, Patientenaufklärung etc. entsprechend dem „State of the Art“ beherrschen. In den letzten Jahren erfolgte in vielen Ländern die Etablierung von Spezialeinrichtungen für Patienten mit früher Arthritis. Die an diesen Patienten gewonnenen Erkenntnisse deuten darauf hin, daß die „kritische Periode“, innerhalb derer eine chronische Arthritis möglicherweise reversibel ist, bei 6 bis 12 Wochen liegt.

  18. Molecular evolution of the mitochondrial 12S rRNA in Ungulata (mammalia).

    Science.gov (United States)

    Douzery, E; Catzeflis, F M

    1995-11-01

    The complete 12S rRNA gene has been sequenced in 4 Ungulata (hoofed eutherians) and 1 marsupial and compared to 38 available mammalian sequences in order to investigate the molecular evolution of the mitochondrial small-subunit ribosomal RNA molecule. Ungulata were represented by one artiodactyl (the collared peccary, Tayassu tajacu, suborder Suiformes), two perissodactyls (the Grevy's zebra, Equus grevyi, suborder Hippomorpha; the white rhinoceros, Ceratotherium simum, suborder Ceratomorpha), and one hyracoid (the tree hyrax, Dendrohyrax dorsalis). The fifth species was a marsupial, the eastern gray kangaroo (Macropus giganteus). Several transition/transversion biases characterized the pattern of changes between mammalian 12S rRNA molecules. A bias toward transitions was found among 12S rRNA sequences of Ungulata, illustrating the general bias exhibited by ribosomal and protein-encoding genes of the mitochondrial genome. The derivation of a mammalian 12S rRNA secondary structure model from the comparison of 43 eutherian and marsupial sequences evidenced a pronounced bias against transversions in stems. Moreover, transversional compensatory changes were rare events within double-stranded regions of the ribosomal RNA. Evolutionary characteristics of the 12S rRNA were compared with those of the nuclear 18S and 28S rRNAs. From a phylogenetic point of view, transitions, transversions and indels in stems as well as transversional and indels events in loops gave congruent results for comparisons within orders. Some compensatory changes in double-stranded regions and some indels in single-stranded regions also constituted diagnostic events. The 12S rRNA molecule confirmed the monophyly of infraorder Pecora and order Cetacea and demonstrated the monophyly of the suborder Ruminantia was not supported and the branching pattern between Cetacea and the artiodacytyl suborders Ruminantia and Suiformes was not established. The monophyly of the order Perissodactyla was evidenced

  19. A label-free silicon quantum dots-based photoluminescence sensor for ultrasensitive detection of pesticides.

    Science.gov (United States)

    Yi, Yinhui; Zhu, Gangbing; Liu, Chang; Huang, Yan; Zhang, Youyu; Li, Haitao; Zhao, Jiangna; Yao, Shouzhuo

    2013-12-03

    Sensitive, rapid, and simple detection methods for the screening of extensively used organophosphorus pesticides and highly toxic nerve agents are in urgent demand. A novel label-free silicon quantum dots (SiQDs)-based sensor was designed for ultrasensitive detection of pesticides. This sensing strategy involves the reaction of acetylcholine chloride (ACh) with acetylcholinesterase (AChE) to form choline that is in turn catalytically oxidized by choline oxidase (ChOx) to produce betaine and H2O2 which can quench the photoluminescence (PL) of SiQDs. Upon the addition of pesticides, the activity of AChE is inhibited, leading to the decrease of the generated H2O2, and hence the PL of SiQDs increases. By measuring the increase in SiQDs PL, the inhibition efficiency of pesticide to AChE activity was evaluated. It was found that the inhibition efficiency was linearly dependent on the logarithm of the pesticides concentration. Consequently, pesticides, such as carbaryl, parathion, diazinon, and phorate, were determined with the SiQDs PL sensing method. The lowest detectable concentrations for carbaryl, parathion, diazinon, and phorate reached 7.25 × 10(-9), 3.25 × 10(-8), 6.76 × 10(-8), and 1.9 × 10(-7) g/L, respectively, which were much lower than those previously reported. The detecting results of pesticide residues in food samples via this method agree well with those from high-performance liquid chromatography. The simple strategy reported here should be suitable for on-site pesticides detection, especially in combination with other portable platforms.

  20. 78 FR 95 - Notice of Receipt of Requests for Amendments To Delete Uses in Certain Pesticide Registrations

    Science.gov (United States)

    2013-01-02

    ... Vegetables and Mangos. 82326-1 D-Limonene Limonene........ Outdoor Uses. Technical. Users of these products... for Amendments To Delete Uses in Certain Pesticide Registrations AGENCY: Environmental Protection... uses in certain pesticide registrations. FIFRA provides that a registrant of a pesticide product may at...

  1. Dietary intakes of pesticides based on community duplicate diet samples.

    Science.gov (United States)

    Melnyk, Lisa Jo; Xue, Jianping; Brown, G Gordon; McCombs, Michelle; Nishioka, Marcia; Michael, Larry C

    2014-01-15

    The calculation of dietary intake of selected pesticides was accomplished using food samples collected from individual representatives of a defined demographic community using a community duplicate diet approach. A community of nine participants was identified in Apopka, FL from which intake assessments of organophosphate (OP) and pyrethroid pesticides were made. From these nine participants, sixty-seven individual samples were collected and subsequently analyzed by gas chromatography/mass spectrometry. Measured concentrations were used to estimate dietary intakes for individuals and for the community. Individual intakes of total OP and pyrethroid pesticides ranged from 6.7 to 996 ng and 1.2 to 16,000 ng, respectively. The community intake was 256 ng for OPs and 3430 ng for pyrethroid pesticides. The most commonly detected pesticide was permethrin, but the highest overall intake was of bifenthrin followed by esfenvalerate. These data indicate that the community in Apopka, FL, as represented by the nine individuals, was potentially exposed to both OP and pyrethroid pesticides at levels consistent with a dietary model and other field studies in which standard duplicate diet samples were collected. Higher levels of pyrethroid pesticides were measured than OPs, which is consistent with decreased usage of OPs. The diversity of pyrethroid pesticides detected in food samples was greater than expected. Continually changing pesticide usage patterns need to be considered when determining analytes of interest for large scale epidemiology studies. The Community Duplicate Diet Methodology is a tool for researchers to meet emerging exposure measurement needs that will lead to more accurate assessments of intake which may enhance decisions for chemical regulation. Successfully determining the intake of pesticides through the dietary route will allow for accurate assessments of pesticide exposures to a community of individuals, thereby significantly enhancing the research benefit

  2. Pesticide poisoning in the developing world--a minimum pesticides list

    DEFF Research Database (Denmark)

    Eddleston, Michael; Karalliedde, Lakshman; Buckley, Nick

    2002-01-01

    In parts of the developing world, pesticide poisoning causes more deaths than infectious diseases. Use of pesticides is poorly regulated and often dangerous; their easy availability also makes them a popular method of self-harm. In 1985, the UN Food and Agriculture Organisation (FAO) produced...... a voluntary code of conduct for the pesticide industry in an attempt to limit the harmful effects of pesticides. Unfortunately, a lack of adequate government resources in the developing world makes this code ineffective, and thousands of deaths continue today. WHO has recommended that access to highly toxic...... to do specific tasks within an integrated pest management system. Use of safer pesticides should result in fewer deaths, just as the change from barbiturates to benzodiazepines has reduced the number of deaths from pharmaceutical self-poisoning....

  3. 78 FR 76611 - Pesticide Experimental Use Permit; Notice of Receipt of Application; Comment Request

    Science.gov (United States)

    2013-12-18

    .... Environmental justice. EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement... high and adverse human health impacts or environmental effects from exposure to the pesticide(s... product to be used: maximum of 0.162 milligram (mg) fluoxastrobin per seed with a seed/pound (lb) average...

  4. Luminescence recognition of different organophosphorus pesticides by the luminescent Eu(III)–pyridine-2,6-dicarboxylic acid probe

    International Nuclear Information System (INIS)

    Azab, Hassan A.; Duerkop, Axel; Anwar, Z.M.; Hussein, Belal H.M.; Rizk, Moustafa A.; Amin, Tarek

    2013-01-01

    Highlights: ► Europium (III) luminescence quenching has been used for sensing organophosphorous pesticides. ► Four guest pesticides chlorfenvinphos, malathion, azinphos, and paraxon ethyl were used. ► A sensitive rapid, cheap direct method for the determination of the pesticides has been developed. ► The method was applied to the determination of the OPs in tap, river, mineral, and waste waters. - Abstract: Luminescence quenching of a novel long lived Eu(III)–pyridine-2,6-dicarboxylic acid probe of 1:2 stoichiometric ratio has been studied in 0.10 volume fraction ethanol–water mixture at pH 7.5 (HEPES buffer) in the presence of the organophosphorus pesticides chlorfenvinphos (P1), malathion (P2), azinphos (P3), and paraxon ethyl (P4). The luminescence intensity of Eu(III)–(PDCA) 2 probe decreases as the concentration of the pesticide increases. It was observed that the quenching due to P3 and P4 proceeds via both diffusional and static quenching processes. Direct methods for the determination of the pesticides under investigation have been developed using the luminescence quenching of Eu(III)–pyridine-2,6-dicarboxylic acid probe in solution. The linear range for determination of the selected pesticides is 1.0–35.0 μM. The detection limits were 0.24–0.55 μM for P3, P4, and P1 and 2.5 μM for P2, respectively. The binding constants (K), and thermodynamic parameters of the OPs with Eu(III)–(PDCA) 2 were evaluated. Positive and negative values of entropy (ΔS) and enthalpy (ΔH) changes for Eu(III)–(PDCA) 2 –P1 ternary complex were calculated. As the waters in this study do not contain the above mentioned OPs over the limit detectable by the method, a recovery study was carried out after the addition of the adequate amounts of the organophosphorus pesticides under investigation.

  5. 76 FR 55799 - Mandipropamid; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2011-09-09

    ... on basil, fresh and basil, dried. This action is in response to EPA's granting of an emergency... use of the pesticide on basil. This regulation establishes a maximum permissible level for residues of...-propynyloxy)- benzeneacetamide, in or on basil, fresh at 20 parts per million (ppm) and basil, dried at 240...

  6. 77 FR 8741 - Spirotetramat; Pesticide Tolerances for Emergency Exemptions

    Science.gov (United States)

    2012-02-15

    ... production season with the available insecticides in most areas of onion production. After having reviewed... on onion, dry bulb under section 408(l)(6) of the Federal Food, Drug, and Cosmetic Act (FFDCA), 21 U... pesticide on dry bulb onions. This regulation establishes a maximum permissible level for residues of...

  7. 76 FR 58506 - Pesticide Program Dialogue Committee; Notice of Public Meeting

    Science.gov (United States)

    2011-09-21

    ...: Pesticide industry and trade associations; environmental/public interest, consumer, and animal rights groups... trade associations; environmental, consumer, and farmworker groups; animal welfare organizations...

  8. 77 FR 23245 - Pesticide Program Dialogue Committee; Notice of Public Meeting

    Science.gov (United States)

    2012-04-18

    ... animal rights groups; farm worker organizations; pesticide user, grower, and commodity groups; Federal... trade associations; environmental, consumer, and farm worker groups; animal welfare organizations...

  9. 76 FR 2406 - Notice of Proposed Information Collection: Comment Request Sustainable Communities Regional Grant...

    Science.gov (United States)

    2011-01-13

    ... Information Relay Service (1-800-877-8339). FOR FURTHER INFORMATION CONTACT: Zuleika Morales-Romero, Grants.... Shelley R. Poticha. Director, Office of Sustainable Housing and Communities. [FR Doc. 2011-657 Filed 1-12...

  10. Presence of pesticide residues on produce cultivated in Suriname.

    Science.gov (United States)

    Abdoel Wahid, F; Wickliffe, J; Wilson, M; Van Sauers, A; Bond, N; Hawkins, W; Mans, D; Lichtveld, M

    2017-06-01

    Agricultural pesticides are widely used in Suriname, an upper middle-income Caribbean country located in South America. Suriname imported 1.8 million kg of agricultural pesticides in 2015. So far, however, national monitoring of pesticides in crops is absent. Reports from the Netherlands on imported Surinamese produce from 2010 to 2015 consistently showed that samples exceeded plant-specific pesticide maximum residue limits (MRLs) of the European Union (EU). Consumption of produce containing unsafe levels of pesticide residues can cause neurological disorders, and particularly, pregnant women and children may be vulnerable. This pilot study assessed the presence of pesticide residues in commonly consumed produce items cultivated in Suriname. Thirty-two insecticides (organophosphates, organochlorines, carbamates, and pyrethroids) and 12 fungicides were evaluated for their levels in nine types of produce. Pesticide residue levels exceeding MRLs in this study regarded cypermethrin (0.32 μg/g) in tomatoes (USA MRL 0.20 μg/g), lambda-cyhalothrin (1.08 μg/g) in Chinese cabbage (USA MRL 0.40 μg/g), endosulfan (0.07 μg/g) in tannia (EU MRL 0.05 μg/g), and lindane (0.02 and 0.03 μg/g, respectively) in tannia (EU MRL 0.01 μg/g). While only a few pesticide residues were detected in this small pilot study, these residues included two widely banned pesticides (endosulfan and lindane). There is a need to address environmental policy gaps. A more comprehensive sampling and analysis of produce from Suriname is warranted to better understand the scope of the problem. Preliminary assessments, using intake rate, hazard quotient, and level of concern showed that it is unlikely that daily consumption of tannia leads to adverse health effects.

  11. Toxicity of sediment-associated pesticides to Chironomus dilutus and Hyalella azteca.

    Science.gov (United States)

    Ding, Yuping; Weston, Donald P; You, Jing; Rothert, Amanda K; Lydy, Michael J

    2011-07-01

    Two hundred sediment samples were collected and their toxicity evaluated to aquatic species in a previous study in the agriculturally dominated Central Valley of California, United States. Pyrethroid insecticides were the main contributors to the observed toxicity. However, mortality in approximately one third of the toxic samples could not be explained solely by the presence of pyrethroids in the matrices. Hundreds of pesticides are currently used in the Central Valley of California, but only a few dozen are analyzed in standard environmental monitoring. A significant amount of unexplained sediment toxicity may be due to pesticides that are in widespread use that but have not been routinely monitored in the environment, and even if some of them were, the concentrations harmful to aquatic organisms are unknown. In this study, toxicity thresholds for nine sediment-associated pesticides including abamectin, diazinon, dicofol, fenpropathrin, indoxacarb, methyl parathion, oxyfluorfen, propargite, and pyraclostrobin were established for two aquatic species, the midge Chironomus dilutus and the amphipod Hyalella azteca. For midges, the median lethal concentration (LC₅₀) of the pesticides ranged from 0.18 to 964 μg/g organic carbon (OC), with abamectin being the most toxic and propargite being the least toxic pesticide. A sublethal growth endpoint using average individual ash-free dry mass was also measured for the midges. The no-observable effect concentration values for growth ranged from 0.10 to 633 μg/g OC for the nine pesticides. For the amphipods, fenpropathrin was the most toxic, with an LC₅₀ of 1-2 μg/g OC. Abamectin, diazinon, and methyl parathion were all moderately toxic (LC₅₀s 2.8-26 μg/g OC). Dicofol, indoxacarb, oxyfluorfen, propargite, and pyraclostrobin were all relatively nontoxic, with LC₅₀s greater than the highest concentrations tested. The toxicity information collected in the present study will be helpful in decreasing the

  12. Determination of malation, methidathion, and chlorpyrifos ethyl pesticides using acetylcholinesterase biosensor based on Nafion/Ag@rGO-NH_2 nanocomposites

    International Nuclear Information System (INIS)

    Guler, Muhammet; Turkoglu, Vedat; Basi, Zehra

    2017-01-01

    Herein, a facile electrochemical acetylcholinesterase (EC 3.1.1.7; AChE) biosensor based on nafion (NA) and Ag nanoparticles supported on amine functionalized reduced graphene oxide (rGO-NH_2) was developed. The Ag@rGO-NH_2 nanocomposite was characterized using Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), and X-ray diffraction (XRD). After being optimized, the biosensor exhibited excellent electrochemical response to the oxidation of thiocholine, the hydrolysis product of acetylthiocholine chloride (ATCl) catalyzed by AChE. An apparent Michealis-Menten value of 20.5 μM was obtained. Under optimized conductions, the biosensor detected malation, methidathion, and chlorpyrifos ethyl in the linear range from 0.0063 to 0.077 μg/mL, from 0.012 to 0.105 μg/mL, and from 0.021 to 0.122 μg/mL, respectively. The detection limit (LoD) was 4.5 ng/mL for malation, 9.5 ng/mL for methidathion, and 14 ng/mL for chlorpyrifos ethyl. Also, the NA/Ag@rGO-NH_2/AChE/GCE biosensor showed god sensitivity, stability and repeatability, which provides a promising tool for the detection of organophosphate pesticides.

  13. Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206 in C2C12 Myocytes and mdx Mice.

    Directory of Open Access Journals (Sweden)

    Yasunari Matsuzaka

    Full Text Available Duchenne muscular dystrophy (DMD is a progressive neuromuscular disorder. Here, we show that the CD63 antigen, which is located on the surface of extracellular vesicles (EVs, is associated with increased levels of muscle-abundant miRNAs, namely myomiRs miR-1, miR-133a, and miR-206, in the sera of DMD patients and mdx mice. Furthermore, the release of EVs from the murine myoblast C2C12 cell line was found to be modulated by intracellular ceramide levels in a Ca2+-dependent manner. Next, to investigate the effects of EVs on cell survival, C2C12 myoblasts and myotubes were cultured with EVs from the sera of mdx mice or C2C12 cells overexpressing myomiRs in presence of cellular stresses. Both the exposure of C2C12 myoblasts and myotubes to EVs from the serum of mdx mice, and the overexpression of miR-133a in C2C12 cells in presence of cellular stress resulted in a significant decrease in cell death. Finally, to assess whether miRNAs regulate skeletal muscle regeneration in vivo, we intraperitoneally injected GW4869 (an inhibitor of exosome secretion into mdx mice for 5 and 10 days. Levels of miRNAs and creatine kinase in the serum of GW4869-treated mdx mice were significantly downregulated compared with those of controls. The tibialis anterior muscles of the GW4869-treated mdx mice showed a robust decrease in Evans blue dye uptake. Collectively, these results indicate that EVs and myomiRs might protect the skeletal muscle of mdx mice from degeneration.

  14. 75 FR 864 - Notice of Receipt of Several Pesticide Petitions Filed for Residues of Pesticide Chemicals in or...

    Science.gov (United States)

    2010-01-06

    ....10 ppm; cattle; meat at 0.10 ppm; cattle; meat byproducts; except liver at 0.10 ppm; cattle; liver at 1.2 ppm; eggs at 0.1 ppm; goat; fat at 0.10 ppm; goat; meat at 0.10 ppm; goat; meat byproducts; except liver at 0.10 ppm; goat; liver at 1.2 ppm; hog; fat at 0.01 ppm; hog; meat at 0.01 ppm; hog; meat...

  15. Soil-food chain-pesticide wildlife relationships in aldrin-treated fields

    Science.gov (United States)

    Korschgen, L.J.

    1970-01-01

    Soil-food-chain-pesticide wildlife relationships were investigated to learn the concentration of pesticide residues present in soils, macro-invertebrates, vertebrates, and seeds as a result of annual applications of aldrin at recommended rates for pest control. Two central Missouri cornfields treated witb aldrin at 1 lb/acre, for 16 and 15 of the past 17 years, were selected for study during 1965-67. Primary samples collected for residue analyses included soils, earthworms (Lumbricidae), crickets (GryIlidae), and two kinds of ground beetles (Carabidae) obtained during early April, June, August, and October. Vertebrates and plant seeds collected during 1967 included white-footed mice (Peromyscus maniculatus), toads (Bufo americanus), snakes (Thamnophis sirtalis and Pituophis sayi), corn (Zea Mays), foxtail (Setaria Faberii), and annual sunflower (Helianthus annuus). Pesticide residues consisted primarily of dieldrin, the degradation product of aldrin. Combined aldrin and dieldrin residues, as two field all-season averages, wet weight basis, were: soils, 0.31 ppm; earthworms, 1.49 ppm; crickets, 0.23 ppm; Harpalus ground beetles, 1.10 ppm; Poecilus ground beetles, 9.67 ppm; white-footed mice, 0.98 ppm; toads, 3.53 ppm; garter snakes, 12.35 ppm; and corn, foxtail, and sunflower seeds less than 0.02 ppm each. Unusually high average residues (37.48 ppm) in Poecilus beetles during June, 1967, were attributed to abnormally high soil moisture and predacious feeding habits of these insects.

  16. 75 FR 68970 - Amendment of Using Agency for Restricted Areas R-4002, R-4005, R-4006 and R-4007; MD

    Science.gov (United States)

    2010-11-10

    ...-1070; Airspace Docket No. 10-AEA-18] RIN 2120-AA66 Amendment of Using Agency for Restricted Areas R-4002, R-4005, R- 4006 and R-4007; MD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action makes a minor change to the name of the using agency for restricted areas R...

  17. Betydelsen av historisk rättvisa efter kolonialismen

    Directory of Open Access Journals (Sweden)

    Göran Collste

    2012-05-01

    Full Text Available Artikeln tar sin utgångspunkt i två aktuella exempel på krav på historisk rättvisa efter kolonialismen: forna Mau-Mau-kämpars krav på gottgörelse för britternas övergrepp på 1950-talet och hererofolkets krav till Tyskland på gottgörelse för det folkmord som ägde rum 1904–1907. Dessa exempel aktualiserar frågan om historisk rättvisa. Vad innebär historisk rättvisa? Vilka krav på historisk rättvisa är berättigade att ställa? Hur lång tid efter övergrepp och våld finns det skäl att kräva gottgörelse? Kan kraven ärvas till efterkommande generationer? Vem bör gottgöra dem som drabbats? Dessa frågor måste besvaras för att man skall kunna ta ställning till krav på gottgörelse och rättvisa. Syftet med denna artikel är att identifiera och söka besvara en rad frågor som krav på gottgörande rättvisa efter kolonialismen ställer. Avslutningsvis diskuteras kraven från Mau-Mau-kämparna som var internerade i brittiska läger och hererofolkets krav på kompensation från Tyskland.Nyckelord: Gottgörande rättvisa, kompensation, kolonialism, herero, Mau-Mau, global rättvisa, historisk rättvisaEnglish summary: The Meaning of Historical Justice after ColonialismRecently, four Kikuyus and former Kenyan Mau-Mau fighters claimed compensation for castration, torture and rape committed in the British detention camps in the 1950s. Also recently, representatives of the Herero people went to Berlin to bring home skulls that Germans brought to Berlin after the genocide at the beginning of the Twentieth Century. The detentions and abuses of Kikuyu and the genocide of the Herero people are just two examples of offenses carried out by European nations during colonialism. Do these offenses have any reverberations today? Should we simply forget about the deeds that happened such a long time ago or do they raise any legal or moral questions?The concept of justice has two dimensions, distributional and rectificatory. This

  18. U.S. EPA, Pesticide Product Label, SEVIN 5% DUST, 11/19/1981

    Science.gov (United States)

    2011-04-21

    ... "e;;t~~i~:i'·:,~r:.;~. eT~;:': i:, .O~~~:~J It;;;'"lh~''I~;.rP:~,~: t;~~ ';JI.~~ n>nl~ .nd "',"'nlll frU'1 m"lh KPI>I .. d( 1',",41 r.11 and .""rv II) to 14 ...

  19. 12 CFR 541.10 - Dwelling unit.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Dwelling unit. 541.10 Section 541.10 Banks and... FEDERAL SAVINGS ASSOCIATIONS § 541.10 Dwelling unit. The term dwelling unit means the unified combination of rooms designed for residential use by one family, other than a single-family dwelling. ...

  20. 78 FR 18585 - FIFRA Pesticide Registration Review and ESA Consultation Processes; Stakeholder Input; Notice of...

    Science.gov (United States)

    2013-03-27

    ... Review and ESA Consultation Processes; Stakeholder Input; Notice of Availability AGENCY: Environmental... describing enhanced opportunities for stakeholder input during its review of pesticide registrations under... announcing the availability of a document titled, ``Enhancing Stakeholder Input in the Pesticide Registration...

  1. Confirmed organophosphorus and carbamate pesticide poisonings in South African wildlife (2009–2014

    Directory of Open Access Journals (Sweden)

    Christo J. Botha

    2015-12-01

    Full Text Available During a six-year period (from January 2009 to December 2014, specimens collected from 344 cases of suspected organophosphorus and carbamate pesticide poisonings in wildlife, including birds, were submitted to the Toxicology Laboratory (ARC-OVI for analysis. A positive diagnosis was made in 135 (39% of these cases. The majority of cases were from birds, which included Cape vultures (Gyps coprotheres and African white-backed vultures (Gyps africanus and bateleur eagles (Terathopius ecaudatus. In one incident 49 vultures were killed when a farmer intentionally laced carcasses with carbofuran in an attempt to control jackal predation. There were 22 incidents of poisoning in helmeted guineafowl (Numida meleagris. On nine different occasions blue cranes (Anthropoides paradiseus were poisoned, in one incident 14 birds were reported to have been killed. Over the period of investigation, there were 20 cases of poisoning involving mammalian species, the majority being vervet monkeys (Chlorocebus pygerythrus. The carbamate pesticides were responsible for 57 incidents of poisoning. Aldicarb, carbofuran and methomyl were detected in 26, 18 and 12 cases respectively. The majority of organophosphorus pesticide poisonings were caused by diazinon (n = 19, monocrotophos (n = 13 and methamidophos (n = 10.

  2. Effect of grass cover on water and pesticide transport through undisturbed soil columns, comparison with field study (Morcille watershed, Beaujolais)

    Energy Technology Data Exchange (ETDEWEB)

    Dousset, S., E-mail: sylvie.dousset@limos.uhp-nancy.f [Nancy-Universite, CNRS, LIMOS, BP 70239, 54506 Vandoeuvre-les-Nancy (France); Thevenot, M. [Universite de Lille 1, CNRS, Geosystemes, 59655 Villeneuve d' Ascq (France); Schrack, D. [INRA-SAD ASTER, 88500 Mirecourt (France); AFSSA, Laboratoire d' Etudes et de Recherches en Hydrologie, 54000 Nancy (France); Gouy, V.; Carluer, N. [UR Milieux Aquatiques, Ecologie et Pollution, Cemagref, 69336 Lyon Cedex (France)

    2010-07-15

    The purpose of this work is to assess the effectiveness of two grass covers (buffer zone and grass-covered inter-row), to reduce pesticide leaching, and subsequently to preserve groundwater quality. Lower amounts of pesticides leached through grass-cover soil columns (2.7-24.3% of the initial amount) than the bare soil columns (8.0-55.1%), in correspondence with their sorption coefficients. Diuron was recovered in higher amounts in leachates (8.9-32.2%) than tebuconazole (2.7-12.9%), in agreement with their sorption coefficients. However, despite having a sorption coefficient similar to that of diuron, more procymidone was recovered in the leachates (10.2-55.1%), probably due to its facilitated transport by dissolved organic matter. Thus even in this very permeable soil, higher organic matter contents associated with grass-cover reduce the amount of pesticide leaching and limit the risk of groundwater contamination by the pesticides. The results of diuron and tebuconazole transfer through undisturbed buffer zone soil columns are in agreement with field observations on the buffer zone. - Grass-covered soils reduce the amount of pesticide leaching, due mainly to their higher organic matter contents, thereby reducing the risk of groundwater contamination.

  3. Effect of grass cover on water and pesticide transport through undisturbed soil columns, comparison with field study (Morcille watershed, Beaujolais)

    International Nuclear Information System (INIS)

    Dousset, S.; Thevenot, M.; Schrack, D.; Gouy, V.; Carluer, N.

    2010-01-01

    The purpose of this work is to assess the effectiveness of two grass covers (buffer zone and grass-covered inter-row), to reduce pesticide leaching, and subsequently to preserve groundwater quality. Lower amounts of pesticides leached through grass-cover soil columns (2.7-24.3% of the initial amount) than the bare soil columns (8.0-55.1%), in correspondence with their sorption coefficients. Diuron was recovered in higher amounts in leachates (8.9-32.2%) than tebuconazole (2.7-12.9%), in agreement with their sorption coefficients. However, despite having a sorption coefficient similar to that of diuron, more procymidone was recovered in the leachates (10.2-55.1%), probably due to its facilitated transport by dissolved organic matter. Thus even in this very permeable soil, higher organic matter contents associated with grass-cover reduce the amount of pesticide leaching and limit the risk of groundwater contamination by the pesticides. The results of diuron and tebuconazole transfer through undisturbed buffer zone soil columns are in agreement with field observations on the buffer zone. - Grass-covered soils reduce the amount of pesticide leaching, due mainly to their higher organic matter contents, thereby reducing the risk of groundwater contamination.

  4. Implications of extreme flatness in a general f(R theory

    Directory of Open Access Journals (Sweden)

    Michał Artymowski

    2016-09-01

    Full Text Available We discuss a modified gravity theory defined by f(R=∑nlαnM2(1−nRn. We consider both finite and infinite number of terms in the series while requiring that the Einstein frame potential of the theory has a flat area around any of its stationary points. We show that the requirement of maximally flat stationary point leads to the existence of the saddle point (local maximum for even (odd l. In both cases for l→∞ one obtains the Starobinsky model with small, exponentially suppressed corrections. Besides the GR minimum the Einstein frame potential has an anti de Sitter vacuum. However we argue that the GR vacuum is absolutely stable and AdS can be reached neither via classical evolution nor via quantum tunnelling. Our results show that a Starobinsky-like model is the only possible realisation of f(R theory with an extremely flat area in the Einstein frame potential.

  5. VizieR Online Data Catalog: PTF 12dam & iPTF 13dcc follow-up (Vreeswijk+, 2017)

    Science.gov (United States)

    Vreeswijk, P. M.; Leloudas, G.; Gal-Yam, A.; De Cia, A.; Perley, D. A.; Quimby, R. M.; Waldman, R.; Sullivan, M.; Yan, L.; Ofek, E. O.; Fremling, C.; Taddia, F.; Sollerman, J.; Valenti, S.; Arcavi, I.; Howell, D. A.; Filippenko, A. V.; Cenko, S. B.; Yaron, O.; Kasliwal, M. M.; Cao, Y.; Ben-Ami, S.; Horesh, A.; Rubin, A.; Lunnan, R.; Nugent, P. E.; Laher, R.; Rebbapragada, U. D.; Wozniak, P.; Kulkarni, S. R.

    2017-08-01

    Spectroscopic follow-up observations of PTF 12dam were performed with the Kast Spectrograph at the Lick 3m Shane telescope, and the Low Resolution Imaging Spectrograph (LRIS) at the Keck-I 10m telescope (on Mauna Kea, Hawaii) on 2012 May 20, 21, and 22. The full spectroscopic sequence of PTF 12dam will be presented by R. M. Quimby et al. (2016, in preparation). PTF 12dam was imaged with the Palomar Oschin 48 inch (P48) (i)PTF survey telescope in the Mould R filter, the Palomar 60 inch (P60) and CCD camera in Johnson B and Sloan Digital Sky Survey (SDSS) gri, the Las Cumbres Observatory Global Telescope Network (LCOGT) in SDSS r, and LRIS mounted on the 10m Keck-I telescope in Rs. iPTF 13dcc has not had any exposure in the literature yet. It was flagged as a transient source on 2013 August 29. Spectroscopic follow-up observations spanning 2013 Nov 26 to 2014 Jan 16 were performed with the Double Spectrograph (DBSP) at the Palomar 200 inch (P200), LRIS at Keck-I, and the Inamori-Magellan Areal Camera & Spectrograph (IMACS) at the Magellan Baade telescope, showing iPTF 13dcc to be an SLSN at z=0.4305. iPTF 13dcc was imaged with the P48 Oschin (i)PTF survey telescope in the Mould R filter, the P60 in SDSS gri, the 4.3m Discovery Channel Telescope (DCT, at Lowell Observatory, Arizona) with the Large Monolithic Imager (LMI) in SDSS ri, and finally with the Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) Wide-Field Camera using filter F625W (under program GO-13858; P.I. A. De Cia). (3 data files).

  6. Evaluation of pesticide toxicities with differing mechanisms using Caenorhabditis elegans.

    Science.gov (United States)

    Ruan, Qin-Li; Ju, Jing-Juan; Li, Yun-Hui; Liu, Ran; Pu, Yue-Pu; Yin, Li-Hong; Wang, Da-Yong

    2009-01-01

    The aim of this study was to (1) determine whether model organism Caenorhabditis elegans was sensitive to pesticides at the maximum concentration limits regulated by national agency standards, and (2) examine the multi-biological toxicities occurring as a result of exposure to pesticides. Five pesticides, namely, chlorpyrifos, imibacloprid, buprofezin, cyhalothrin, and glyphosate, with four different mechanisms of action were selected for the investigation. In accordance with national agency requirements, 4 exposed groups were used for each tested pesticide with the concentration scales ranging from 1.0 x 10(-3) to 1 mg/L. L4 larvae were exposed for 24 and 72 h, respectively. Endpoints of locomotion, propagation, and development were selected for the assay as parameters of toxicity. After exposure for 24 h, both the body bend frequency and head thrash frequency of nematodes exposed to chlorpyrifos, imibacloprid, and cyhalothrin decreased in a concentration-dependent manner, and there were significant differences between exposed groups at maximum concentration level (MCL) compared to control. The generation time of nematodes exposed to buprofezin 24 h significantly increased in a concentration-dependent manner in the highest exposed group. When exposed for 72 h, the body bend frequency and head thrash frequency of nematodes exposed to cyhalothrin markedly decreased at MCL. The generation time and brood size of nematodes exposed to buprofezin were reduced in a concentration-dependent manner. The behavior of nematodes was sensitive to pesticides with neurotoxic properties, while pesticides affecting insect growth modified the reproductive system. The effects of pesticides on nematodes exposed for 24 h appeared more sensitive than with exposure for 72 h. Caenorhabditis elegans may thus be used for assessing the adverse effects of pesticide residues in aquatic environment.

  7. Substitution of the CFCs R-11, R-13, R-503, R-13B1, R-113, R-114 and R-12B1 in existing refrigerating, air-conditioning and heat pump systems with refrigerants of low ozone depletion potential in the Federal Republic of Germany. Status report; Ersatz der FCKW R11, R13, R503, R13B1, R113, R114, und R12B1 in bestehenden Kaelte-, Klima- und Waermepumpenanlagen in der Bundesrepublik Deutschland durch Kaeltemittel mit geringem Ozonabbaupotential. Statusbericht

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The technical basics and the state of the art for the substitution of the CFC refrigerants R-11, R-13, R-503, R-13B1, R-113, R-114 and R-12B1 in existing refrigeration systems are described and explained. The report contains an overview of the current applications of these refrigerants in the FRG, a review and discussion of existing substitutes, the presentation and evaluation of research and experiences with the conversion to alternative refrigerants, the presentation of the required infrastructure and a discussion of the technical feasibility. The conversion of existing systems to refrigerants of lower ozone depletion potential is in conclusion evaluated with regard to its technical feasibility, environmental relevance and economic efficiency. (orig.) [Deutsch] Es werden die technischen Grundlagen und der Stand der Technik zum Ersatz der FCKW-Kaeltemittel R11, R13, R503, R13B1, R113, R114 und R12B1 in bestehenden Kaelteanlagen dargestellt und erlaeutert. Der Bericht beinhaltet einen Ueberblick ueber die derzeitige Anwendung dieser Kaeltemittel in der BRD, die Vorstellung und Diskussion existierender Ersatzstoffe, die Darstellung und Bewertung der Forschung und Erfahrungen zu Umruestungen auf Ersatzstoffe, die Vorstellung der erforderlichen Infrastruktur und die Diskussion der technischen Durchfuehrbarkeit. Die Umstellung bestehender Anlagen auf Kaeltemittel mit geringerem Ozonabbaupotential wird abschliessend hinsichtlich der technischen Durchfuehrbarkeit, der Umweltrelevanz und der Wirtschaftlichkeit bewertet. (orig.)

  8. 75 FR 52340 - Fenoxycarb; Notice of Receipt of Request To Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-08-25

    ... of Request To Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection... registrants to voluntarily cancel registrations of products containing the pesticide fenoxycarb. The request... listed in this notice will be permitted after the registrations have been canceled only if such sale...

  9. 75 FR 28019 - Resmethrin; Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-05-19

    ... of Requests to Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection... registrants to voluntarily cancel their registrations of certain products containing the pesticide resmethrin... after the registration has been cancelled only if such sale, distribution, or use is consistent with the...

  10. 76 FR 46805 - Notice of Utah Adoption by Reference of the Pesticide Container Containment Rule

    Science.gov (United States)

    2011-08-03

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9447-8] Notice of Utah Adoption by Reference of the Pesticide Container Containment Rule AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: This... Pesticide Container Containment (PCC) Rule regulations. In accordance with State of Utah Agricultural Code...

  11. The brain imaging study of the organophosphorus pesticides poisoning

    International Nuclear Information System (INIS)

    Yang Yanmei; Liu Huaijun; Li Shuling; Wang Yongsheng; Huang Boyuan; Chi Cen; Shi Zhenyang; Cui Caixia; Zhou Lixia; Liu Runtian

    2004-01-01

    Objective: To summarize the CT and MR imaging findings in acute organophosphorus pesticides poisoning patients, and to improve the early diagnostic ability. Methods: The imaging of 34 patients of organophosphorus pesticides poisoning was analyzed, the poisons were all taken orally. The pesticides included methamidophos (12 cases), omethoate (15 cases), DDV (3 cases), and methylparathion (4 cases). According to the diagnosis and classification diagnosis criterion of acute organophosphorus pesticides poisoning, the patients were divided into two groups: mild or moderate grade group (24 cases) and severe grade group (10 cases). The relationship between the clinic grade and CT and MRI findings was studied. Results: in the severe grade group, 4 patients showed brain edema, presenting as sulcus and fissure flattened or disappeared, and ventricles and cisterns narrowed or closed 2-3 days after poisoning. In 3 patients 3 days to 3 months after poisoning, bilateral basal ganglion and cerebral cortex showed prolonged T 1 and T 2 signals, and high signal intensity was detected on FLAIR, and bilateral basal ganglion low density was revealed on CT. T 1 relaxation was shortened, T 2 WI and FLAIR imaging showed high signal intensity in 1 patient. The imaging of 1 patient 6 months after poisoning showed the cerebral sulcus, fissure and ventricle were enlarged. CT and MRI in the mild or moderate group were normal. By the Fisher's exact probabilities test, the imaging exhibition difference between the severe grade and mild or moderate grade patients was significant. Conclusion: The CT and MRI can reflect the brain injury after poisoning, and the imaging exhibitions were various. The imaging information can provide credible foundation for the therapy for lightening the brain edema and nourishing the brain cell

  12. Mechanism underlying the effect of long-term exposure to low dose of pesticides on DNA integrity.

    Science.gov (United States)

    Alleva, Renata; Manzella, Nicola; Gaetani, Simona; Bacchetti, Tiziana; Bracci, Massimo; Ciarapica, Veronica; Monaco, Federica; Borghi, Battista; Amati, Monica; Ferretti, Gianna; Tomasetti, Marco

    2018-04-01

    Pesticides, including herbicides, insecticides and fungicides, are widely used in intensive agriculture. Recently, the long-term effects of pesticide exposure were found to be associated with many diseases. In this study, we evaluated the long-term effect of low-level exposure to a mixture of pesticides on DNA damage response (DDR) in relation to individual detoxifying variability. A residential population chronically exposed to pesticides was enrolled, biological/environmental pesticide levels; paroxonase 1 (PON-1) activity and 192 Q/R polymorphism and DDR were evaluated at three different periods of pesticide exposure. OGG1-dependent DNA repair activity was decreased in relation to pesticide exposure. The increase of DNA lesions and pesticide levels in the intensive pesticide-spraying period was independent on PON-1 activity. Next, human bronchial epithelial and neuronal cells were used as a model for in vitro evaluation of the mechanistic effect of pesticides. Pesticides induced mitochondrial dysfunction leading to ROS formation. ROS from mitochondria induced DNA damage, which in turn induced OGG1-dependent DNA repair activity through 8-oxoguanine DNA glycosylase 1 (OGG1) expression and activation. Even though OGG1 was overexpressed, an inhibition of its activity, associated with DNA lesion accumulation, was found at prolonged pesticide-exposure. A post-translational regulation of OGG1 by pesticide may be postulated. Taken together, long-term exposure to low-levels of pesticides affects DDR resulting in accumulation of DNA lesions that eventually may lead to cancer or neurological disorders. © 2018 Wiley Periodicals, Inc.

  13. Pesticide regulations and farm worker safety: the need to improve pesticide regulations in Viet Nam.

    Science.gov (United States)

    Phung, Dung Tri; Connell, Des; Miller, Greg; Rutherford, Shannon; Chu, Cordia

    2012-06-01

    Agricultural pesticide use in Viet Nam has more than tripled since 1990. However, pesticide legislation and regulations have not been developed in response to this large increase in usage, as a result of which pesticides pose a serious threat to human health and the environment. This paper identifies the need to improve pesticide regulations in Viet Nam through a comparative analysis of pesticide regulations in Viet Nam and the United States of America, where the rate of acute poisoning among agricultural workers is much lower than in Viet Nam and where information pertaining to pesticide regulations is made accessible to the public. The analysis identified several measures that would help to improve Viet Nam's pesticide regulations. These include enhancing pesticide legislation, clarifying the specific roles and active involvement of both the environmental and health sectors; performing a comprehensive risk-benefit evaluation of pesticide registration and management practices; improving regulations on pesticide suspension and cancellation, transport, storage and disposal; developing import and export policies and enhancing pesticide-related occupational safety programmes.

  14. 77 FR 40880 - Agrobacterium radiobacter; Registration Review Proposed Decision; Notice of Availability

    Science.gov (United States)

    2012-07-11

    ...: Ann Sibold, Regulatory Action Leader, Biopesticides and Pollution Prevention Division (7511P), Office... pathogen Agrobacterium tumefaciens) when applied to seeds, roots and/or stems of nonbearing fruit, nut and.... Matthews, Director, Biopesticides and Pollution Prevention Division, Office of Pesticide Programs. [FR Doc...

  15. Computer program for distance learning of pesticide application technology

    Directory of Open Access Journals (Sweden)

    Bruno Maia

    2011-12-01

    Full Text Available Distance learning presents great potential for mitigating field problems on pesticide application technology. Thus, due to the lack of teaching material about pesticide spraying technology in the Portuguese language and the increasing availability of distance learning, this study developed and evaluated a computer program for distance learning about the theory of pesticide spraying technology using the tools of information technology. The modules comprising the course, named Pulverizar, were: (1 Basic concepts, (2 Factors that affect application, (3 Equipments, (4 Spraying nozzles, (5 Sprayer calibration, (6 Aerial application, (7 Chemigation, (8 Physical-chemical properties, (9 Formulations, (10 Adjuvants, (11 Water quality, and (12 Adequate use of pesticides. The program was made available to the public on July 1st, 2008, hosted at the web site www.pulverizar.iciag.ufu.br, and was simple, robust and practical on the complementation of traditional teaching for the education of professionals in Agricultural Sciences. Mastering pesticide spraying technology by people involved in agricultural production can be facilitated by the program Pulverizar, which was well accepted in its initial evaluation.O ensino à distância apresenta grande potencial para minorar os problemas ocorridos no campo na área de tecnologia de aplicação de agroquímicos. Dessa forma, diante da escassez de material instrucional na área de tecnologia de aplicação de agroquímicos em Português e do crescimento elevado da educação à distância, o objetivo deste trabalho foi desenvolver e avaliar um programa computacional para o ensino à distância da parte teórica de tecnologia de aplicação de agroquímicos, utilizando as ferramentas de tecnologia da informação. Os módulos que compuseram o curso, intitulado Pulverizar, foram: (1 Conceitos básicos, (2 Fatores que afetam a aplicação, (3 Equipamentos, (4 Pontas de pulverização, (5 Calibração de pulverizadores

  16. Exposure to pesticides and diabetes: A systematic review and meta-analysis.

    Science.gov (United States)

    Evangelou, Evangelos; Ntritsos, Georgios; Chondrogiorgi, Maria; Kavvoura, Fotini K; Hernández, Antonio F; Ntzani, Evangelia E; Tzoulaki, Ioanna

    2016-05-01

    Diabetes mellitus has a multifactorial pathogenesis with a strong genetic component as well as many environmental and lifestyle influences. Emerging evidence suggests that environmental contaminants, including pesticides, might play an important role in the pathogenesis of diabetes. We performed a systematic review and meta-analysis of observational studies that assessed the association between exposure to pesticides and diabetes and we examined the presence of heterogeneity and biases across available studies. A comprehensive literature search of peer-reviewed original research pertaining to pesticide exposure and diabetes, published until 30st May 2015, with no language restriction, was conducted. Eligible studies were those that investigated potential associations between pesticides and diabetes without restrictions on diabetes type. We included cohort studies, case-control studies and cross-sectional studies. We extracted information on study characteristics, type of pesticide assessed, exposure assessment, outcome definition, effect estimate and sample size. We identified 22 studies assessing the association between pesticides and diabetes. The summary OR for the association of top vs. bottom tertile of exposure to any type of pesticide and diabetes was 1.58 (95% CI: 1.32-1.90, p=1.21×10(-6)), with large heterogeneity (I(2)=66.8%). Studies evaluating Type 2 diabetes in particular (n=13 studies), showed a similar summary effect comparing top vs. bottom tertiles of exposure: 1.61 (95% CI 1.37-1.88, p=3.51×10(-9)) with no heterogeneity (I(2)=0%). Analysis by type of pesticide yielded an increased risk of diabetes for DDE, heptachlor, HCB, DDT, and trans-nonachlor or chlordane. The epidemiological evidence, supported by mechanistic studies, suggests an association between exposure to organochlorine pesticides and Type 2 diabetes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Degradation of contrasting pesticides by white rot fungi and its relationship with ligninolytic potential.

    Science.gov (United States)

    Bending, Gary D; Friloux, Maxime; Walker, Allan

    2002-06-18

    The capacity of nine species of white rot fungus from a variety of basidiomycete orders to degrade contrasting mono-aromatic pesticides was investigated. There was no relationship between degradation of the dye Poly R-478, a presumptive test for ligninolytic potential, and degradation of the highly available pesticides diuron, metalaxyl, atrazine or terbuthylazine in liquid culture. However, there were significant positive correlations between the rates of degradation of the different pesticides. Greatest degradation of all the pesticides was achieved by Coriolus versicolor, Hypholoma fasciculare and Stereum hirsutum. After 42 days, maximum degradation of diuron, atrazine and terbuthylazine was above 86%, but for metalaxyl less than 44%. When grown in the organic matrix of an on-farm "biobed" pesticide remediation system, relative degradation rates of the highly available pesticides by C. versicolor, H. fasciculare and S. hirsutum showed some differences to those in liquid culture. While H. fasciculare and C. versicolor were able to degrade about a third of the poorly available compound chlorpyrifos in biobed matrix after 42 days, S. hirsutum, which was the most effective degrader of the available pesticides, showed little capacity to degrade the compound.

  18. 75 FR 22404 - Clofencet; Notice of Receipt of Request to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-04-28

    ... Request to Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... voluntarily cancel their registrations of certain products containing the pesticide clofencet. The request... cancelled only if such sale, distribution, or use is consistent with the terms as described in the final...

  19. 76 FR 36535 - Dicofol; Notice of Receipt of Request To Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2011-06-22

    ... Request To Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... registrants to voluntarily cancel their registrations of all products containing the pesticide dicofol. The... the registrations have been cancelled only if such sale, distribution, or use is consistent with the...

  20. 75 FR 24697 - Carbaryl; Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-05-05

    ... Requests To Voluntarily Cancel Certain Pesticide Registrations AGENCY: Environmental Protection Agency (EPA... voluntarily cancel their registrations of certain products containing the pesticide carbaryl. The requests... of products listed in this notice will be permitted after the registration has been canceled only if...