WorldWideScience

Sample records for four-year efficacy cosmesis

  1. Efficacy and safety of rufinamide in children under four years of age with drug-resistant epilepsies.

    Science.gov (United States)

    Grosso, Salvatore; Coppola, Giangennaro; Dontin, Serena Donetti; Gobbi, Giuseppe; Pruna, Dario; Accorsi, Patrizia; Verrotti, Alberto; Parisi, Pasquale; Balestri, Paolo

    2014-09-01

    Studies on the efficacy and tolerability of rufinamide in infants and young children are scarce. Here we report on an open, retrospective, and pragmatic study about safety and efficacy of rufinamide in children aged less than four years, in terms of seizures types and epilepsy syndromes. Forty children (mean age 39.5 months; range 22-48) were enrolled in the study. The mean follow-up period was 12.2 months (range 5-21). Rufinamide was initiated at a mean age of 26.7 months (range 12-42). Final rufinamide mean dosage was 31.5 mg/kg/day if associated with valproic acid and 44.2 mg/kg/day if not. The highest seizure reduction rate was observed in the epileptic spasms (46%) and drop attacks (42%) groups. Seizure reduction was also observed in tonic seizures (35%) and in the focal seizure (30%) groups. In terms of epilepsy syndrome, rufinamide was effective in Lennox-Gastaut syndrome. Results were very poor for those affected by Dravet's syndrome. Globally, responder rate was 27.5%, including two (5%) patients seizure-free. Adverse reactions occurred in 37.5% of children and were mainly represented by vomiting, drowsiness, irritability, and anorexia. Discontinuation rate due to treatment-emergent adverse events was 15%. The present study concludes that rufinamide may be a safe and effective drug for a broad range of seizures and epilepsy syndromes in infants and young children and represents a valid therapeutic option in this population. Copyright © 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  2. Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial

    DEFF Research Database (Denmark)

    Dillner, Joakim; Kjaer, Susanne K; Wheeler, Cosette M;

    2010-01-01

    To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata)....

  3. Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial

    DEFF Research Database (Denmark)

    Dillner, Joakim; Kjaer, Susanne K; Wheeler, Cosette M;

    2010-01-01

    To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata).......To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata)....

  4. Facial nerve palsy: Providing eye comfort and cosmesis

    Directory of Open Access Journals (Sweden)

    Alsuhaibani Adel

    2010-01-01

    Full Text Available Development of facial nerve palsy (FNP may lead to dramatic change in the patient′s facial function, expression, and emotions. The ophthalmologist may play an important role in the initial evaluation, and the long-term management of patients with new-onset of FNP. In patients with expected temporary facial weakness, no efforts should be wasted to ensure proper corneal protection. Patients with permanent functional deficit may require combination of surgical procedures tailored to the patient′s clinical findings that may require good eye comfort and cosmesis.

  5. Facial Nerve Palsy: Providing Eye Comfort and Cosmesis

    Science.gov (United States)

    Alsuhaibani, Adel H.

    2010-01-01

    Development of facial nerve palsy (FNP) may lead to dramatic change in the patient's facial function, expression, and emotions. The ophthalmologist may play an important role in the initial evaluation, and the long-term management of patients with new-onset of FNP. In patients with expected temporary facial weakness, no efforts should be wasted to ensure proper corneal protection. Patients with permanent functional deficit may require combination of surgical procedures tailored to the patient's clinical findings that may require good eye comfort and cosmesis. PMID:20616921

  6. Four years in / four years out : two university buildings 2000-2008

    Energy Technology Data Exchange (ETDEWEB)

    Lovell, J. [Royal Inst. of British Architects, London (United Kingdom); Washington Univ., St. Louis, MO (United States). Graduate School of Architecture and Urban Design

    2009-07-01

    The University of Cambridge commissioned London-based Allies and Morrison to develop and design 2 new buildings for its Sidgwick campus, England. Two naturally ventilated buildings were completed and occupied in 2004. The Estate Management and Building Service at the University of Cambridge is now reviewing the actual energy performance of both buildings in terms of user comfort. The finding will be compared against original projections of the design team. The review will also compare actual running costs against projected costs and feedback from building users and facilities management. The approach taken by client and design team towards the life-time energy performance of the building was examined in terms of comfort and control and load management. A more complex system of sub-metering is now proposed for all new buildings. Post occupancy feedback data was used to evaluate the successes and failures of the project teams in terms of energy performance, thermal comfort and building management communication four years after completion. This paper noted that if viewed over 30 years, the initial construction budget of a building accounts for only a fraction of the true cost of a building. During its lifetime, primary expenditure will likely to be upon personnel costs; work performance and salaries, staff retention and absenteeism. Therefore, the success of a building must be seen in the context of its whole life and the comfort of its users. 14 refs., 9 figs.

  7. Motor Proficiency Predicts Cognitive Ability in Four-Year-Olds

    Science.gov (United States)

    Hernandez, Amanda Martinez; Caçola, Priscila

    2015-01-01

    Research has shown links between motor proficiency and cognition in school-age children, however, few have explored earlier ages. We aimed to determine the association between motor proficiency and cognitive ability in four-year-olds. Motor and cognitive skills were examined in 32 (15 males, 17 females) four-year-olds (±5.59 months) using the…

  8. Four-Year State Colleges: The Scope of Collective Bargaining.

    Science.gov (United States)

    Kramer, Gerald H.; Creswell, John W.

    Examined are the written collective bargaining agreements that existed during any part or all of the 1973-74 academic year between four-year state colleges and faculties who have chosen bargaining agents. All of the written agreements in effect at four-year state colleges, a total of fourteen covering thirty-seven institutions, were analyzed. The…

  9. Automating the AFROTC Four-Year Scholarship Program.

    Science.gov (United States)

    1986-04-01

    34 -" ’ . ", "- . ,, -,V~’ : . l . ’ "" "* ’ i ,-.,-. - . i’s. , - ;# ’ - , - ’ d -. - -...- .. *1 h’. I - AFROTC FOUR-YEAR SCHOLARSUEP DATA ENTRY (S.. Pdta Act Stateumf

  10. PetroChina Sees Gas Pipeline Profit in Four Years

    Institute of Scientific and Technical Information of China (English)

    Xiao Lu

    2002-01-01

    @@ Sebei-Xining- Lanzhou pipeline put into operation PetroChina, the nation's largest gas producer,recently said that the US$280-million gas pipeline in Northwest China would generate profits within four years.

  11. Four Years of Portability: Perspectives on a Laptop Program.

    Science.gov (United States)

    Barrett, Joanne

    2002-01-01

    Reviews a laptop computer technology program that has been in effect for nearly four years in a middle school in Bethesda, Maryland. Topics include initial opposition from parents; benefits to teachers, students, and learning; copyright issues; problems with plagiarism; accessibility; accountability; and email issues. (LRW)

  12. Laterality and Motor Skills in Four-Year-Olds.

    Science.gov (United States)

    Tan, Lesley E.

    1985-01-01

    Compared four-year-old left-handed children and children lacking definite hand preference with right-handers on motor skills. Found no differences between left-handers and right-handers of either sex, but the children lacking hand preference had lower scores. Possible sex differences and implications for the education of children lacking…

  13. The Hidden Costs of Low Four-Year Graduation Rates

    Science.gov (United States)

    Sullivan, Daniel F.

    2010-01-01

    The single most important step colleges and universities--especially public colleges and universities--can take to lower the student and family cost of college attendance is to improve retention, thereby increasing the four-year graduation rate. The author believes that institutions with high rates of retention to graduation have those high rates…

  14. Partnerships Between TYCs and Four-Year Institutions

    Science.gov (United States)

    Clay, Keith; Sabella, Mel; Price, Edward

    2012-02-01

    We are faced with a severe shortage of certificated STEM teachers, especially in physics. At the present time, four year institutions are struggling to address this shortage with only a handful of schools graduating two or more physics educators each year. The science education community must therefore focus more attention on the important role of the two year college (TYC), where one third to one half of our STEM majors begin their college careers. In this session, we will explore the obstacles and prospects for recruiting math and science teachers from TYCs from the perspectives of three institutions who are interested in developing meaningful collaborations between the TYC and the four year institution. Group discussions will consider options and look for solutions.

  15. Video-EEG recording: a four-year clinical audit.

    LENUS (Irish Health Repository)

    O'Rourke, K

    2012-02-03

    In the setting of a regional neurological unit without an epilepsy surgery service as in our case, video-EEG telemetry is undertaken for three main reasons; to investigate whether frequent paroxysmal events represent seizures when there is clinical doubt, to attempt anatomical localization of partial seizures when standard EEG is unhelpful, and to attempt to confirm that seizures are non-epileptic when this is suspected. A clinical audit of all telemetry performed over a four-year period was carried out, in order to determine the clinical utility of this aspect of the service and to determine means of improving effectiveness in the unit. Analysis of the data showed a high rate of negative studies with no attacks recorded. Of the positive studies approximately 50% showed non-epileptic attacks. Strategies for improving the rate of positive investigations are discussed.

  16. Four+ Years of Measurements from the Mendenhall Glacier Terminus

    Science.gov (United States)

    Heavner, M.; Fatland, D. R.

    2012-12-01

    We describe the instrumentation, power, communications, and lessons learned from ongoing four+ years of measurements at the terminus of Mendenhall Glacier. In this presentation we focus on the most successful microserver deployment. The microserver is a simple rugged computer with a radio modem that can survive and operate outdoors in harsh environments like Antarctica. The system is called a microserver because of the networking capabilities, particularly as it may act as anchor points for localized lightweight sensor networks. SEAMONSTER, the SouthEast Alaska MOnitoring Network for Science, Technology, Education and Research, is a demonstration sensor web effort. The microserver design for SEAMONSTER is intended to provide general capabilities that could be used in harsh environments specifically for cryospheric observations. At the Mendenhall terminus the observations included meteorologic data and repeat digital photography. Other SEAMONSTER stations included snow accumulation and density, precision GPS, seismic, water pressure, and other measurements. Power generation at the Mendenhall deployment is both solar and wind.

  17. The Romanian economy - four years after the EU accession

    Directory of Open Access Journals (Sweden)

    Laurian LUNGU

    2011-12-01

    Full Text Available The first four years of Romania’s membership confirmed that the accession to the EU had, overall, positive effects on the economy. Although the pace of structural reforms had slowed down after 2007, they picked up again after the start of financial crisis, at the end of 2008. Households’ wealth and purchasing power have increased despite the recent drop over the last two years. Looking ahead, Romania’s economy will need to enhance its competitiveness and pursue a growth model which would make it less dependent on external shocks. Economic strategies leading to both physical and human capital accumulation would need to be clearly defined and supported by all political parties. With monetary policy aimed at maintaining price stability, fiscal policy would have a defining role in preserving and enhancing competitiveness. The pursuance of sound fiscal and monetary policies would be paramount in achieving sustained growth in the years to come.

  18. Analyzing the Bitcoin Network: The First Four Years

    Directory of Open Access Journals (Sweden)

    Matthias Lischke

    2016-03-01

    Full Text Available In this explorative study, we examine the economy and transaction network of the decentralized digital currency Bitcoin during the first four years of its existence. The objective is to develop insights into the evolution of the Bitcoin economy during this period. For this, we establish and analyze a novel integrated dataset that enriches data from the Bitcoin blockchain with off-network data such as business categories and geo-locations. Our analyses reveal the major Bitcoin businesses and markets. Our results also give insights on the business distribution by countries and how businesses evolve over time. We also show that there is a gambling network that features many very small transactions. Furthermore, regional differences in the adoption and business distribution could be found. In the network analysis, the small world phenomenon is investigated and confirmed for several subgraphs of the Bitcoin network.

  19. FACT. More than four years of blazar monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Dorner, Daniela [Universitaet Wuerzburg (Germany); Collaboration: FACT-Collaboration

    2016-07-01

    Since October 2011, the First G-APD Cherenkov Telescope (FACT) has been collecting more than 5500 hours of physics data. Thanks to the silicon based photosensors (SiPMs, aka G-APDs), observations during bright ambient light like full moon can be carried out without degradation of the sensors. Keeping the gain of the SiPMs stable using an online feedback system, a stable and homogeneous detector performance is achieved. Based on this and an automatic data taking procedure, an unbiased longterm data sample is collected. An automatic quick look analysis provides results shortly after the data are taken allowing to send flare alerts within the same night. The main targets for FACT are the bright TeV blazars Mrk 421 and Mrk 501 which are monitored since January 2012. In addition, several other sources like for example the Crab Nebula, 1ES 1959+650, 1ES 2344+54.1 are observed. In this presentation, the results from more than four years of monitoring are summarized. Several flares from Mrk 501 and Mrk 421 are discussed in the multi-wavelength (MWL) context. Mrk 501 underwent major outbursts in June 2012 and June 2014 during the yearly MWL campaigns. Mrk 421 showed a bright flare in April 2013 where also MWL observations are available. 1ES 1959+650 showed enhanced flux in autumn 2015. Results from these observations are discussed.

  20. Four years of Ulysses dust data 1996 to 1999

    CERN Document Server

    Krüger, H; Landgraf, M; Dermott, S; Fechtig, H; Gustafson, B A; Hamilton, D P; Hanner, M S; Horányi, M; Kissel, J; Lindblad, B A; Linkert, D; Linkert, G; Mann, I; McDonnell, J A M; Morfill, G E; Polanskey, C; Schwehm, G; Srama, R A; Zook, H A

    2001-01-01

    The Ulysses spacecraft is orbiting the Sun on a highly inclined ellipse ($ i = 79^{\\circ}$, perihelion distance 1.3 AU, aphelion distance 5.4 AU). Between January 1996 and December 1999 the spacecraft was beyond 3 AU from the Sun and crossed the ecliptic plane at aphelion in May 1998. In this four-year period 218 dust impacts were recorded with the dust detector on board. We publish and analyse the complete data set of both raw and reduced data for particles with masses $\\rm 10^{-16} g$ to $\\rm 10^{-8}$ g. Together with 1477 dust impacts recorded between launch of Ulysses and the end of 1995 published earlier \\cite{gruen1995c,krueger1999b}, a data set of 1695 dust impacts detected with the Ulysses sensor between October 1990 and December 1999 is now available. The impact rate measured between 1996 and 1999 was relatively constant with about 0.2 impacts per day. The impact direction of the majority of the impacts is compatible with particles of interstellar origin, the rest are most likely interplanetary parti...

  1. Interplanetary dust. [survey of last four years' research

    Science.gov (United States)

    Brownlee, D. E.

    1979-01-01

    Progress in the study of interplanetary dust during the past four years is reviewed. Attention is given to determinations of the relative contributions of interstellar dust grains, collisional debris from the asteroid belt and short-period comets to the interplanetary dust cloud. Effects of radiation pressure and collisions on particle dynamics are discussed, noting the discovery of the variation of the orbital parameters of dust particles at 1 AU with size and in situ measurements of dust density between 0.3 and 5 AU by the Helios and Pioneer spacecraft. The interpretation of the zodiacal light as produced by porous absorbing particles 10 to 100 microns in size is noted, and measurements of the Doppler shift, light-producing-particle density, UV spectrum, photometric axis and angular scattering function of the zodiacal light are reported. Results of analyses of lunar rock microcraters as to micrometeoroid density, flux rate, size distribution and composition are indicated and interplanetary dust particles collected from the stratosphere are discussed. Findings concerning the composition of fragile meteoroid types found as cosmic spherules in deep sea sediments are also presented.

  2. Postural changes in dental hygienists. Four-year longitudinal study.

    Science.gov (United States)

    Barry, R M; Woodall, W R; Mahan, J M

    1992-01-01

    Numerous surveys identify the occurrence of musculoskeletal complaints as a concern in dentistry. However, no longitudinal data exist to indicate whether postural changes occur as a result of practicing dental hygiene. The purpose of this preliminary, four-year longitudinal study was to investigate whether any postural changes developed during the hygienists' clinical education and/or during subsequent dental hygiene practice after one and/or two years. It was anticipated that the awkward positions and intense physical demands placed on hygienists might initiate musculoskeletal problems, but that no postural changes would occur over this short period of time. Nine of 10 dental hygienists in the graduating class of 1987 were surveyed for existing musculoskeletal complaints, and the subjects were photographed for a measurement of postural change. Responses from participants indicated an increase in musculoskeletal-related complaints in each of the six areas investigated. The photographic findings indicated that one of the nine hygienists showed an increase in forward head posture, a postural change.

  3. Priming overgeneralizations in two- and four-year-old children.

    Science.gov (United States)

    Gershkoff-Stowe, Lisa; Connell, Brenda; Smith, Linda

    2006-08-01

    Overgeneralization occurs when a child uses the wrong word to name an object and is often observed in the early stages of word learning. We develop a method to elicit overgeneralizations in the laboratory by priming children to say the names of objects perceptually similar to known and unknown target objects. Experiment 1 examined 18 two-year-old children's labelling of familiar and unfamiliar objects, using a name that was previously produced. Experiment 2 compared the labelling of 30 two-year-olds and 39 four-year-olds when presented with completely novel objects. The findings suggest that the retrieved word is a blend of previous activation from the prior retrieval and activation engendered by the similarity of the test object to instances of the target category. We put forward a theoretical account of overgeneralization based on current models of adult language processing. The account suggests a common mechanism of activation and retrieval, which may explain not only momentary lapses in the correct selection of words, but other types of naming errors traditionally thought to reflect differences in children's underlying category representations or, perhaps, gaps in their knowledge of words.

  4. [The health of industrial employees four years after compulsory redundancy].

    Science.gov (United States)

    Beale, N; Nethercott, S

    1987-09-01

    A controlled, longitudinal study of the health of workers made redundant when a meat products factory closed has been performed using morbidity data extracted from the records of a group general practice. Increases in consultation rates and the number of visits to hospital outpatient departments in the group made redundant are contrasted with opposite trends in a control group who remained securely employed. As in earlier findings, the increases in morbidity in the study group began when they learned that their jobs were in jeopardy.The subsequent employment history of those made redundant was obtained by questionnaire. In the four years after redundancy, 50 of the 76 men in-the study group found new full-time jobs. The other 26 men remained out of work for most of this time or were made redundant once again. This 'jobless' group consulted their general practitioners 57% more often about 13% more illnesses, were referred to hospital outpatient departments 63% more often and visited hospital 208% more frequently than when enjoying secure employment. During an intervening two-year period of job insecurity, there were increases of 45%, 9%, 25% and 28% respectively, for this jobless group.The implications of these findings for primary care, for the National Health Service and for future research are discussed in the present context of high levels of unemployment.

  5. Thirty-four years' experience with biliary atresia in Denmark

    DEFF Research Database (Denmark)

    Kvist, N; Davenport, M

    2011-01-01

    Biliary atresia (BA) is a rare disease in Denmark (population ∼ 5.5 million) and there has been some controversy on how smaller countries should manage such conditions to obtain the best possible outcomes. The aim of this study was to evaluate the efficacy of primary surgery (i. e., Kasai...

  6. Thirty-four years' experience with biliary atresia in Denmark

    DEFF Research Database (Denmark)

    Kvist, N; Davenport, M

    2011-01-01

    Biliary atresia (BA) is a rare disease in Denmark (population ~¿5.5 million) and there has been some controversy on how smaller countries should manage such conditions to obtain the best possible outcomes. The aim of this study was to evaluate the efficacy of primary surgery (i.¿e., Kasai...

  7. [Career satisfaction of German medical residents after four years of training].

    Science.gov (United States)

    Römer, Farina; Ziegler, Stine; Scherer, Martin; van den Bussche, Hendrik

    2017-02-01

    To evaluate German residents' career satisfaction and its dependency on intrinsic and extrinsic factors after four years of postgraduate training. Gender, parental status, training conditions and specialty choice were of particular interest. Postal questionnaires were sent to medical graduates from seven different German faculties annually, starting in 2009. This paper presents cross-sectional data of domestic, working and training conditions four years after graduation. We used descriptive statistics and t-tests. In order to identify factors with an impact on career satisfaction, multiple regression analyses were calculated. Male residents who have children tended to be more satisfied with their career than residents without children. For female residents, however, having children was associated with lower career satisfaction. Those who chose training in general surgery or orthopedic surgery were less satisfied with their career progress. Residents with prolonged specialty training showed lower career satisfaction. Junior doctors who rated the quality of their residency training higher were more satisfied with their career. Those who perceived their job as particularly demanding were less satisfied. Concerning intrinsic factors, occupational self-efficacy and overall satisfaction with life were significantly associated with career satisfaction. Residents in general are quite satisfied with their career after four years of training. Opportunities to work part-time during residency as well as structured training programs should be implemented in order to overcome parenthood as a career obstacle for female residents. The quality of specialty training is particularly important for career satisfaction and has to be ensured across specialties. Copyright © 2017. Published by Elsevier GmbH.

  8. Skin toxicity and cosmesis after hypofractionated whole breast irradiation for early breast cancer.

    Science.gov (United States)

    Saksornchai, Kitwadee; Rojpornpradit, Prayuth; Shotelersak, Kanjana; Lertbutsayanukul, Chawalit; Chakkabat, Chakkapong; Raiyawa, Tassapong

    2012-02-01

    To assess and compare the impact on skin reactions and cosmesis between hypofractionated whole breast and conventional irradiation for early breast cancer. Seventy-three patients with operable breast cancer (pT1-3pN0-1M0) who underwent breast-conserving surgery were assigned for irradiation to either conventional arm (50 Gy in 25 fractions) with a sequential electron boost of 15-16 Gy over five weeks or hypofractionated arm (43.2 Gy in 16 fractions) with a concomitant electron boost of 0.6 Gy over three weeks. At 3-week follow-up, skin toxicities in the hypofractionated arm were significantly worse than that seen in the conventional arm, while at 6-week follow-up, the percentages of skin toxicities in the conventional arm were higher After a median follow-up of six months, there was no significant difference in skin toxicities between the two treatment groups. In addition, there were no significant differences in the mean scores of cosmetic outcome for patients between two regimens. This hypofractionated radiotherapy regimen of 43.2 Gy in 16 fractions with a concomitant electron boost showed good results in terms of normal tissue effects and cosmesis. A long-term follow-up is needed to confirm these favorable results.

  9. Failure rate and cosmesis of immediate tissue expander/implant breast reconstruction after postmastectomy irradiation.

    Science.gov (United States)

    Baschnagel, Andrew M; Shah, Chirag; Wilkinson, J Ben; Dekhne, Nayana; Arthur, Douglas W; Vicini, Frank A

    2012-12-01

    This study reports the rate of breast reconstruction failure and cosmetic outcomes after postmastectomy radiation therapy (PMRT) with temporary tissue expanders (TEs) or implants in place. Ninety-four patients underwent mastectomy (93 unilateral, 1 bilateral; 95 cases total) and immediate TE reconstruction followed by PMRT. Ninety TEs and 5 permanent implants were irradiated. All patients received a dose of 5400 cGy given in 180-cGy fractions to the reconstructed breast. Twenty-one patients (22%) received tangents alone and 74 patients (78%) were treated with tangents and a supraclavicular field using a monoisocentric technique. Bolus was used in 91 patients (96%). Eighty-eight patients (93%) received chemotherapy and 78 patients (82%) received endocrine therapy. With a median follow-up of 24.1 months, 19 patients (20%) experienced failure of reconstruction. The 1-, 2-, and 3-year actuarial rate of reconstruction failure was 9.7%, 19.3%, and 25.5%, respectively. Infection was the most common cause of failure. Of the 19 failures, 8 patients underwent salvage procedures with flap reconstruction. Univariate analysis was performed examining age, chemotherapy use, hormone therapy use, use of a supraclavicular field, smoking status, diabetes, hypertension, and menopausal status. No risk factors were found to be associated with reconstruction failure. In patients who did not experience reconstruction failure, good/excellent cosmesis was observed in 75% of patients. In the current series of women with a high risk of locoregional recurrence, PMRT with a TE/implant in place provides good cosmesis in the majority of women, with an acceptable risk of expander or implant loss. Copyright © 2012 Elsevier Inc. All rights reserved.

  10. The Cost of College Attrition at Four-Year Colleges & Universities. Policy Perspectives

    Science.gov (United States)

    Raisman, Neal

    2013-01-01

    This report, an analysis of 1669 U.S. institutions, is a first-time study of the relationship of attrition to revenues lost in four-year public, private, and for-profit colleges and universities on an annual basis. The report is the result of a study investigating the financial impact of attrition on four-year colleges and universities. Other…

  11. Survey on the Transferability of Associate's Degree to Four-Year Institutions.

    Science.gov (United States)

    Rubi, David C.

    In January 1994, the Arizona State Board of Directors for Community Colleges (ASBDCC) conducted a survey of state four-year systems nationwide to determine the existence of standards regarding the transferability of associate degrees and associate degree students' academic standing at receiving four-year institutions. Questionnaires were mailed to…

  12. Five-Year Outcomes, Cosmesis, and Toxicity With 3-Dimensional Conformal External Beam Radiation Therapy to Deliver Accelerated Partial Breast Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Rodríguez, Núria, E-mail: nrodriguez@parcdesalutmar.cat [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Universidad Pompeu Fabra, Barcelona (Spain); Sanz, Xavier [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Universidad Pompeu Fabra, Barcelona (Spain); Dengra, Josefa [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Foro, Palmira [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Universidad Pompeu Fabra, Barcelona (Spain); Membrive, Ismael; Reig, Anna [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Quera, Jaume [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Universidad Pompeu Fabra, Barcelona (Spain); Fernández-Velilla, Enric; Pera, Óscar; Lio, Jackson; Lozano, Joan [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Algara, Manuel [Department of Radiation Oncology, Hospital de la Esperanza, Parc de Salut MAR, Barcelona (Spain); Universidad Pompeu Fabra, Barcelona (Spain)

    2013-12-01

    Purpose: To report the interim results from a study comparing the efficacy, toxicity, and cosmesis of breast-conserving treatment with accelerated partial breast irradiation (APBI) or whole breast irradiation (WBI) using 3-dimensional conformal external beam radiation therapy (3D-CRT). Methods and Materials: 102 patients with early-stage breast cancer who underwent breast-conserving surgery were randomized to receive either WBI (n=51) or APBI (n=51). In the WBI arm, 48 Gy was delivered to the whole breast in daily fractions of 2 Gy, with or without additional 10 Gy to the tumor bed. In the APBI arm, patients received 37.5 Gy in 3.75 Gy per fraction delivered twice daily. Toxicity results were scored according to the Radiation Therapy Oncology Group Common Toxicity Criteria. Skin elasticity was measured using a dedicated device (Multi-Skin-Test-Center MC-750-B2, CKelectronic-GmbH). Cosmetic results were assessed by the physician and the patients as good/excellent, regular, or poor. Results: The median follow-up time was 5 years. No local recurrences were observed. No significant differences in survival rates were found. APBI reduced acute side effects and radiation doses to healthy tissues compared with WBI (P<.01). Late skin toxicity was no worse than grade 2 in either group, without significant differences between the 2 groups. In the ipsilateral breast, the areas that received the highest doses (ie, the boost or quadrant) showed the greatest loss of elasticity. WBI resulted in a greater loss of elasticity in the high-dose area compared with APBI (P<.05). Physician assessment showed that >75% of patients in the APBI arm had excellent or good cosmesis, and these outcomes appear to be stable over time. The percentage of patients with excellent/good cosmetic results was similar in both groups. Conclusions: APBI delivered by 3D-CRT to the tumor bed for a selected group of early-stage breast cancer patients produces 5-year results similar to those achieved with

  13. 点阵激光在面部美容中的疗效观察%Clinical Study of the Effect of Point Lattice Laser in Facial Cosmesis

    Institute of Scientific and Technical Information of China (English)

    张俊; 牟行蓉; 江捷

    2012-01-01

    Objective: To evaluate the efficacy of point lattice laser in facial cosmetic treatment. Methods: 158 patients accepted the facial cosmetic treatment through the point lattice laser from October 2009 to August 2010, in which there were 52 cases of wrinkles, 43 cases of large pores, 35 cases of colored spot and 28 cases of skin rejuvenation treatment. Results: The total effective rate was 94%, the cure rate was 58%, and the significant effective rate was 86%. Skin rsjuvenation treatment has a good effect, which is followed by large pores,wrinkles and colored spot. Conclusion: The application of point lattice laser in facial cosmesis has a significant effect.%目的:评价点阵激光在面部美容中的疗效.方法:从2009年10月~2010年8月,用点阵激光进行面部美容158例,其中皱纹52例,毛孔粗大43例,色斑35例,嫩肤28例.结果:总有效率为94%,痊愈率为58%,显效率为86%.效果最好为嫩肤,其次是毛孔粗大、皱纹、色斑.结论:点阵激光在面部美容中疗效显著.

  14. Strategic laparoscopic surgery for improved cosmesis in general and bariatric surgery: analysis of initial 127 cases.

    Science.gov (United States)

    Nguyen, Ninh T; Smith, Brian R; Reavis, Kevin M; Nguyen, Xuan-Mai T; Nguyen, Brian; Stamos, Michael J

    2012-05-01

    Strategic laparoscopic surgery for improved cosmesis (SLIC) is a less invasive surgical approach than conventional laparoscopic surgery. The aim of this study was to examine the feasibility and safety of SLIC for general and bariatric surgical operations. Additionally, we compared the outcomes of laparoscopic sleeve gastrectomy with those performed by the SLIC technique. In an academic medical center, from April 2008 to December 2010, 127 patients underwent SLIC procedures: 38 SLIC cholecystectomy, 56 SLIC gastric banding, 26 SLIC sleeve gastrectomy, 1 SLIC gastrojejunostomy, and 6 SLIC appendectomy. SLIC sleeve gastrectomy was initially performed through a single 4.0-cm supraumbilical incision with extraction of the gastric specimen through the same incision. The technique evolved to laparoscopic incisions that were all placed within the umbilicus and suprapubic region. There were no 30-day or in-hospital mortalities or 30-day re-admissions or re-operations. For SLIC cholecystectomy, gastric banding, appendectomy, and gastrojejunostomy, conversion to conventional laparoscopy occurred in 5.3%, 5.4%, 0%, and 0%, respectively; there were no major or minor postoperative complications. For SLIC sleeve gastrectomy, there were no significant differences in mean operative time and length of hospital stay compared with laparoscopic sleeve gastrectomy; 1 (3.8%) of 26 SLIC patients required conversion to five-port laparoscopy. There were no major complications. Minor complications occurred in 7.7% in the SLIC sleeve group versus 8.3% in the laparoscopic sleeve group. SLIC in general and bariatric operations is technically feasible, safe, and associated with a low rate of conversion to conventional laparoscopy. Compared with laparoscopic sleeve gastrectomy, SLIC sleeve gastrectomy can be performed without a prolonged operative time with comparable perioperative outcomes.

  15. A spike at benefit exhaustion: Still possible after four years of unemployment

    DEFF Research Database (Denmark)

    Lyk-Jensen, Stéphanie; Weatherall, Cecilie Dohlmann

    European policymakers wonder whether the long-term unemployed can still find jobs if the benefit period is shortened. We investigate this question by analysing how long-term unemployed react to the threat of running out of unemployment insurance (UI) after receiving it for almost four years....... The empirical analysis is based on very precise administrative records of men’s unemployment spells. To identify the effect of UI exhaustion, we exploit a legislative change in the duration of benefits that progressively reduced UI entitlement from five to four years. Our results show a spike 3-6 months before...... benefit exhaustion for long-term unemployed....

  16. Librarian integration in a four-year medical school curriculum: a timeline.

    Science.gov (United States)

    MacEachern, Mark; Townsend, Whitney; Young, Kristen; Rana, Gurpreet

    2012-01-01

    The Taubman Health Sciences Library (THL) is integrated in all four years of the University of Michigan Medical School (UMMS) curriculum. Information resources are introduced at strategic points throughout the curriculum so that students receive training at times when they are most likely to need the resource. Most of the core instruction sessions are taught in teams that consist of librarians and UMMS faculty, which provides unique learning opportunities for students. This article describes each THL instruction activity in the four-year undergraduate UMMS curriculum and provides commentary on the overall effectiveness of this integrated approach to instruction.

  17. Cosmesis and body image after single-port laparoscopic or conventional laparoscopic cholecystectomy: a multicenter double blinded randomised controlled trial (SPOCC-trial

    Directory of Open Access Journals (Sweden)

    Vonlanthen René

    2011-09-01

    Full Text Available Abstract Background Emerging attempts have been made to reduce operative trauma and improve cosmetic results of laparoscopic cholecystectomy. There is a trend towards minimizing the number of incisions such as natural transluminal endoscopic surgery (NOTES and single-port laparoscopic cholecystectomy (SPLC. Many retrospective case series propose excellent cosmesis and reduced pain in SPLC. As the latter has been confirmed in a randomized controlled trial, patient's satisfaction on cosmesis is still controversially debated. Methods/Design The SPOCC trial is a prospective, multi-center, double blinded, randomized controlled study comparing SPLC with 4-port conventional laparoscopic cholecystectomy (4PLC in elective surgery. The hypothesis and primary objective is that patients undergoing SPLC will have a better outcome in cosmesis and body image 12 weeks after surgery. This primary endpoint is assessed using a validated 8-item multiple choice type questionnaire on cosmesis and body image. The secondary endpoint has three entities: the quality of life 12 weeks after surgery assessed by the validated Short-Form-36 Health Survey questionnaire, postoperative pain assessed by a visual analogue scale and the use of analgesics. Operative time, surgeon's experience with SPLC and 4PLC, use of additional ports, conversion to 4PLC or open cholecystectomy, length of stay, costs, time of work as well as intra- and postoperative complications are further aspects of the secondary endpoint. Patients are randomly assigned either to SPLC or to 4PLC. Patients as well as treating physicians, nurses and assessors are blinded until the 7th postoperative day. Sample size calculation performed by estimating a difference of cosmesis of 20% (alpha = 0.05 and beta = 0.90, drop out rate of 10% resulted in a number of 55 randomized patients per arm. Discussion The SPOCC-trial is a prospective, multi-center, double-blind, randomized controlled study to assess cosmesis and body

  18. Self-Repair of Speech by Four-Year-Old Finnish Children

    Science.gov (United States)

    Salonen, Tuuli; Laakso, Minna

    2009-01-01

    The aim of this study was to examine what four-year-old children repair in their speech. For this purpose, conversational self-repairs (N = 316) made by two typically developing Finnish-speaking children (aged 4 ; 8 and 4 ; 11) were examined. The data comprised eight hours of natural interactions videotaped at the children's homes. The tapes were…

  19. Building a Four Year Post-Secondary Curriculum in Educational Science and Technology.

    Science.gov (United States)

    Plomp, Tjeerd; Verhagen, Plon

    This report begins by providing background information on educational technology in the Netherlands, differences between a four-year program in the Netherlands and undergraduate programs in the United States, and the structure of Dutch university programs. The need for a Department of Educational Science and Technology at the Twente University of…

  20. Four-Year Myth: Make College More Affordable. Restore the Promise of Graduating on Time

    Science.gov (United States)

    Complete College America, 2014

    2014-01-01

    In American higher education, it has become the accepted standard to measure graduation rates at four-year colleges on a six-year time frame. Evaluations of two-year community colleges are now based on three-year graduation rates. Metrics like these are unacceptable, especially when we consider that students and their families are trying…

  1. A Four-Year Follow-Up Study of Underachieving College Freshmen

    Science.gov (United States)

    Valine, Warren J.

    1976-01-01

    A four-year follow-up study of underachieving college freshmen measured changes in the self-concept of those still in college and those who had dropped out. Significant differences generally favored college seniors. Findings also indicate that dropping out of college may be a positive experience. (Author)

  2. Impact of a four-year wellness programme on coronary artery ...

    African Journals Online (AJOL)

    Impact of a four-year wellness programme on coronary artery disease risk in ... African Journal for Physical Activity and Health Sciences ... Employees were monitored for changes in total cholesterol (TC), high-density lipoprotein cholesterol (HDL), ... LDL/HDL ratio, fasting blood glucose (BG), systolic blood pressure (SBP), ...

  3. Reliability of Objective Structured Clinical Examinations: Four Years of Experience in a Surgical Clerkship.

    Science.gov (United States)

    Mann, Karen V.; And Others

    1990-01-01

    Four years of experience with an objective structured clinical examination (OSCE) following an eight-week surgical clerkship (n=356 students) are reported, including data on mean student performance across years, reliability coefficients, and generalizability. Implications for improvement and development of OSCE are discussed. (Author/MSE)

  4. Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy

    NARCIS (Netherlands)

    Geerts, AT; Niermeijer, JMF; Arts, WFM; Brouwer, OF; Stroink, H; Peeters, EAJ; van Donselaar, CA

    2005-01-01

    Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51% achieved a terminal remission of at least 2 years without medication and 21% with medication; 15% had seizures during the fourth year. Early medication withdrawal i

  5. The Fermi GBM Gamma-Ray Burst Spectral Catalog: Four Years of Data

    NARCIS (Netherlands)

    Gruber, D.; Goldstein, A.; Weller von Ahlefeld, V.; Bhat, N.P.; Bissaldi, E.; Briggs, M.S.; Byrne, D.; Cleveland, W.H.; Connaughton, V.; Diehl, R.; Fishman, G.J.; Fitzpatrick, G.; Foley, S.; Gibby, M.; Giles, M.M.; Greiner, J.; Guiriec, S.; van der Horst, A.J.; von Kienlin, A.; Kouveliotou, C.; Layden, E.; Lin, L.; Meegan, C.A.; McGlynn, S.; Paciesas, W.S.; Pelassa, V.; Preece, R.D.; Rau, A.; Wilson-Hodge, C.A.; Xiong, S.; Younes, G.; Yu, H-F.

    2014-01-01

    In this catalog we present the updated set of spectral analyses of gamma-ray bursts (GRBs) detected by the Fermi Gamma-Ray Burst Monitor during its first four years of operation. It contains two types of spectra, time-integrated spectral fits and spectral fits at the brightest time bin, from 943

  6. Enhancing Software Engineering Education through Open Source Projects: Four Years of Students' Perspectives

    NARCIS (Netherlands)

    Papadopoulos, P.M.; Stamelos, I.G.; Meiszner, A.

    2015-01-01

    This paper presents the results after four years of running of an instructional method that utilizes free/libre open source software (FLOSS) projects as tools for teaching software engineering in formal education. In the last four academic years, a total of 408 juniors majoring in Informatics (in a

  7. The Fermi GBM Gamma-Ray Burst Spectral Catalog: Four Years of Data

    NARCIS (Netherlands)

    Gruber, D.; Goldstein, A.; Weller von Ahlefeld, V.; Bhat, N.P.; Bissaldi, E.; Briggs, M.S.; Byrne, D.; Cleveland, W.H.; Connaughton, V.; Diehl, R.; Fishman, G.J.; Fitzpatrick, G.; Foley, S.; Gibby, M.; Giles, M.M.; Greiner, J.; Guiriec, S.; van der Horst, A.J.; von Kienlin, A.; Kouveliotou, C.; Layden, E.; Lin, L.; Meegan, C.A.; McGlynn, S.; Paciesas, W.S.; Pelassa, V.; Preece, R.D.; Rau, A.; Wilson-Hodge, C.A.; Xiong, S.; Younes, G.; Yu, H-F.

    2014-01-01

    In this catalog we present the updated set of spectral analyses of gamma-ray bursts (GRBs) detected by the Fermi Gamma-Ray Burst Monitor during its first four years of operation. It contains two types of spectra, time-integrated spectral fits and spectral fits at the brightest time bin, from 943 tri

  8. A Critical Reflection: Foster Care Youth Experiences at a Four Year Postsecondary Institution

    Science.gov (United States)

    Greer, Renada D.

    2016-01-01

    Foster care youth face significant challenges to postsecondary educational success, especially while enrolled at four-year institutions. Foster care youth are absent of family support that their non-foster peers receive throughout the college experience. Without family support, foster care youth encounter greater challenges to persevere through…

  9. Accelerating the transition to employment at benefit exhaustion: Still possible after four years of unemployment?

    DEFF Research Database (Denmark)

    Vincent, Stéphanie; Weatherall, Cecilie Dohlmann; Geerdsen, Lars Pico

    2017-01-01

    This paper provides evidence of how the long-term unemployed react to the threat of running out of unemployment insurance (UI) after receiving it for nearly four years. To identify the effect of UI exhaustion, we make use of a 1999 Danish legislative change that progressively reduced potential be...

  10. Four years experience with filtration systems in commercial nurseries for eliminating Phytophthora species from recirculation water

    Science.gov (United States)

    T. Ufer; M. Posner; H.-P. Wessels; S. Wagner; K. Kaminski; T. Brand; Werres S.

    2008-01-01

    In a four year project, three different filtration systems were tested under commercial nursery conditions to eliminate Phytophthora spp. from irrigation water. Five nurseries were involved in the project. Slow sand filtration systems were tested in three nurseries. In the fourth nursery, a filtration system with lava grains (Shieer® Bio filtration)...

  11. Predictors of Bachelor's Degree Completion among Rural Students at Four-Year Institutions

    Science.gov (United States)

    Byun, Soo-yong; Irvin, Matthew J.; Meece, Judith L.

    2012-01-01

    Using the National Education Longitudinal Study, this study explored various factors that predicted bachelor's degree attainment among rural youth attending a four-year institution. Results showed that Hispanic origin, family income, parental educational expectations, the rigor of the high school curriculum, timing and intensity of college…

  12. Positive Youth Development through an Outdoor Physical Activity Programme: Evidence from a Four-Year Evaluation

    Science.gov (United States)

    Armour, Kathleen; Sandford, Rachel

    2013-01-01

    In 2006, Sandford, Armour and Warmington undertook a comprehensive review of the literature on the role of physical activity/sport and physical education in promoting positive development for disaffected youth. This paper revisits the findings of the literature review in light of data from a four-year evaluation of one corporate-sponsored physical…

  13. Perceptions and Meanings Constructed by Participants in a Four-Year Instructional Coaching Project

    Science.gov (United States)

    Perry Hummons, Monica

    2012-01-01

    This qualitative study was conducted in the Midwestern U.S. It explored the stories of 27 educators who participated in a four-year instructional coaching project in a large urban school district. Subjects shared their perceptions of and meanings they constructed as a result of their experiences in the coaching project through participation in a…

  14. Performance of Maryland Community College Transfer Students at Public Four-Year College and Universities

    Science.gov (United States)

    Maryland Higher Education Commission, 2011

    2011-01-01

    This data report provides statistics about the number and percentage of Maryland community college students, who earned a bachelor's degree from a public four-year campus in the state within a specified period of years. These students are: (1) Community college students who transferred during the 2004-2005 academic year who received a bachelor's…

  15. Efficiency-Based Funding for Public Four-Year Colleges and Universities

    Science.gov (United States)

    Sexton, Thomas R.; Comunale, Christie L.; Gara, Stephen C.

    2012-01-01

    We propose an efficiency-based mechanism for state funding of public colleges and universities using data envelopment analysis. We describe the philosophy and the mathematics that underlie the approach and apply\\break the proposed model to data from 362 U.S. public four-year colleges and universities. The model provides incentives to institution…

  16. Development of health over four years among middle-aged and older Europeans

    DEFF Research Database (Denmark)

    Vestergaard, Sonja; Eriksen, Mette Lindholm; Andersen-Ranberg, Karen

    2013-01-01

    Older adults in Eastern and Central European countries have a higher risk of developing poor self-rated health over four years. The same geographical pattern is seen for a higher risk of developing hypertension and diabetes. Low educational level significantly increases the risk of developing poor...

  17. Swim Test Requirements at Four-Year Universities in the United States.

    Science.gov (United States)

    Ormond, Frank; And Others

    1997-01-01

    Surveys of 331 four-year universities nationwide examined swim test requirements and reasons for administering or not administering swim tests. Responses from 331 returned questionnaires indicated that 5% of the schools had swim test requirements, though 25% had them previously. Lack of a physical education requirement was the most commonly cited…

  18. After Transfer: The Engagement of Community College Students at a Four-Year Collegiate Institution

    Science.gov (United States)

    Ishitani, Terry T.; McKitrick, Sean A.

    2010-01-01

    This study investigated how educational experiences between community college transfer students and native students differed at a four-year institution. The study sample included groups of native students and community college transfer students, who were further divided by timing of matriculation to the study institution. Benchmarks from National…

  19. Is Articulation from Two- to Four-Year Colleges an Allowed or a Forbidden Transition?

    Science.gov (United States)

    Susskind, Tamar Y.

    1997-01-01

    Argues that patterns of student flow between two- and four-year institutions are not linear and that the permutations of student situations affect the datasets that are used to both defend and question the effectiveness and transferability of two-year programs. (DDR)

  20. The Transfer Playbook: Essential Practices for Two- and Four-Year Colleges

    Science.gov (United States)

    Wyner, Joshua; Deane, K. C.; Jenkins, Davis; Fink, John

    2016-01-01

    With their "open door" admissions policies and lower tuition, community colleges offer a gateway to higher education for millions of American students. Indeed, students who enter higher education through community colleges are much more likely than those who start at four-year institutions to be low-income or the first in their family to…

  1. Web Page Change and Persistence-A Four-Year Longitudinal Study.

    Science.gov (United States)

    Koehler, Wallace

    2002-01-01

    Discussion of changes in the topography of the Web focuses on changes to an existing set of Web documents over a four-year period. Highlights include the life cycle of Web objects; changes to Web objects; measures of change; Web page demise; and Web page changes, including hypertext links, content change, and structural change. (LRW)

  2. A Study of Single Mothers' Experience of Persistence at a Four-Year Public University

    Science.gov (United States)

    Hayes Nelson, Geraldine

    2009-01-01

    The overall purpose of this study was to uncover and describe the barriers that low-income, single mothers between the ages of 17-24 experience and the strategies they adopt in their efforts to persist through year one to year three of college at a four-year public university. Adult education scholarship has shed light on the obstacles to college…

  3. Do Cold Feet Warn of Trouble Ahead? Premarital Uncertainty and Four-Year Marital Outcomes

    OpenAIRE

    Lavner, Justin A.; Karney, Benjamin R.; Bradbury, Thomas N.

    2012-01-01

    Are the doubts that people feel prior to marriage signs of impending difficulties or normative experiences that can be safely ignored? To test these opposing views, we asked 464 recently-married spouses whether they had ever been uncertain about getting married and then compared four-year divorce rates and marital satisfaction trajectories among those partners with and without premarital doubts. Doubts were reported by at least one partner in two-thirds of couples. Women with premarital doubt...

  4. Four-year dynamics of health indicators among the University students who practice Hatha Yoga regularly

    OpenAIRE

    Tolcheva, Hanna; Dudkina, Hanna; Dudkin, Mykhailo

    2016-01-01

    Purpose: to determine the dynamics of a four-year university students in health indicators, regular practice hatha-yoga. Material & Methods: the methods of theoretical analysis, synthesis and compilation of information about the study, physiological and educational testing, pedagogical experiment, methods of mathematical statistics. For experimental verification of developed on hatha-yoga program was formed by a group of 30 students enrolled in the first course of a classical university a...

  5. Policy Commentary/Commentaire BC's Carbon Tax Shift Is Working Well after Four Years (Attention Ottawa)

    OpenAIRE

    Stewart Elgie; Jessica McClay

    2013-01-01

    British Columbia's introduction in 2008 of a revenue-neutral carbon tax shift was controversial. This analysis compares changes in fuel consumption, greenhouse gas emissions, and gross domestic product (GDP) between British Columbia and the rest of Canada. It finds that in the four years since the tax was introduced, British Columbia's per capita consumption of fuels subject to the tax has declined by 19 percent compared to the rest of Canada. At the same time, its economy has kept pace with ...

  6. Post-fire hydrologic response in Central Portugal. A four years study at microplot scale.

    Science.gov (United States)

    Vieira, Diana; Malvar, Maruxa; Martins, Martinho; Machado, Ana; Nunes, João; Keizer, Jacob

    2014-05-01

    Wildfires are a natural phenomenon in regions with a Mediterranean-type climate. However, their present-day widespread occurrence in southern Europe is unprecedented and strongly reflects human activity such as ignition, land-use changes, land abandonment and introduction of highly flammable plantations. Besides wildfires, post-fire management practices such as plowing, terracing, clearcutting and logging should also be considered, since their occurrence is getting increasingly common. And, in a long-term period these practices seem to be executed intercalated with repeated fire occurrences in the same site, sharing the impacts together with fire in an escalated degradational effect. In this sense, the work presented here concerns four years of runoff and erosion data at microplot scale after the wildfire, comparing different land management practices that occurred before the fire. Preliminary results indicate that in four years of monitoring, runoff is constantly higher in plowed sites than in the unplowed ones, with the exception of the first year. Regarding soil losses the plowed plots present always higher sediment rates than the unplowed ones. The comparison between two unplowed sites with different land uses, indicate higher runoff and erosion risk for pine comparatively to the eucalypt ones, however the reduced soil depth in the first can have an important role in these differences. Following these facts, the aim of the present work is to answer the following research questions: i) Do these four years of observations fit with the window of disturbance model presented by Prosser and Williams (1998). or the alternative version by Wittenberg and Inbar (2009)?; ii) Does pre-fire disturbances (wildfire, land use changes and land management practices) still have repercussions after wildfire?; In what sense does four years of intensive monitoring provides that one year couldn't provide?

  7. Contributions of Two-Year Institutions to Four-Year Completions. Snapshot™ Report, Spring 2015

    Science.gov (United States)

    National Student Clearinghouse, 2015

    2015-01-01

    In the 2013-14 academic year, 46 percent of students who completed a degree at a four-year institution were enrolled at a two-year institution at some point in the previous 10 years. This is a one percentage point increase over the comparable figure for degrees awarded in 2010-11. The prior two-year enrollment may have been brief (as little as a…

  8. The four-year dynamics health indicators of students universities regularly practicing hatha-yoga

    Directory of Open Access Journals (Sweden)

    Hanna Tolchieva

    2016-04-01

    Full Text Available Purpose: to determine the dynamics of a four-year university students in health indicators, regular practice hatha-yoga. Material & Methods: the methods of theoretical analysis, synthesis and compilation of information about the study, physiological and educational testing, pedagogical experiment, methods of mathematical statistics. For experimental verification of developed on hatha-yoga program was formed by a group of 30 students enrolled in the first course of a classical university and expressed a desire for a four-year training visit this section three times a week. Age of students before the start of the experiment was 17–18 years old and they did not have special physical training. Results: it was found informative characteristics, which is possible to appreciate the level of health in the student's age. The content of training programs on hatha-yoga for university students who do not have special physical training. Experimentally tested program developed by hatha-yoga with students in universities for four years and recorded the dynamics of their health indicators. Conclusions: quantitative data of the study show the positive impact of regular exercise on hatha-yoga on the body of students. Positive dynamics is set according to the normalization of blood pressure and heart rate, improving posture, reducing excess body weight, improving physical qualities, enhancing the characteristics of the respiratory system.

  9. Enactment of third-party punishment by four-year-olds

    Directory of Open Access Journals (Sweden)

    Ben eKenward

    2012-10-01

    Full Text Available When prompted, preschoolers advocate punishment for moral transgressions against third parties, but little is known about whether and how they might act out such punishment. In this study, adult demonstrators enacted doll stories in which a perpetrator child doll made an unprovoked attack on a victim child doll, after which an adult doll punished either the perpetrator (consistent punishment or victim (inconsistent punishment. When asked to help retell the story, given free choice of their own preferred actions for the adult doll, four-year-olds (N = 32 were influenced by the demonstrated choice of target when selecting a target for punishment or admonishment. This influence was weak following inconsistent punishment, however, because the participants tended to change the story by punishing or admonishing the perpetrator when the demonstrator had punished the victim. Four-year-olds’ tendency to select a moral rule violator as a target for punishment is therefore stronger than their tendency to copy the specific actions of adults, which itself is known to be very strong. The evidence suggests that four-year-olds’ enactment of punishment is at least partially based on a belief that antisocial actions deserve to be punished.

  10. Report on the green paper on energy. Four years of European initiatives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    In December 2000, the European Commission adopted a Green Paper on European Union energy policy. This brochure takes stock of the action undertaken in the following areas over the last four years:managing demand, diversifying internal energy sources,developing the internal energy market and the security of external supply. It presents: the Green Paper stakes, the progress made, the four political challenges, managing demand, diversifying European sources, the streamlined internal energy market, controlling external supply, future prospects for the Union, legislative developments and ten possibilities for economical energy use. (A.L.B.)

  11. A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras

    Directory of Open Access Journals (Sweden)

    Gustavo A Fontecha

    2014-07-01

    Full Text Available Countries could use the monitoring of drug resistance in malaria parasites as an effective early warning system to develop the timely response mechanisms that are required to avert the further spread of malaria. Drug resistance surveillance is essential in areas where no drug resistance has been reported, especially if neighbouring countries have previously reported resistance. Here, we present the results of a four-year surveillance program based on the sequencing of the pfcrt gene of Plasmodium falciparum populations from endemic areas of Honduras. All isolates were susceptible to chloroquine, as revealed by the pfcrt “CVMNK” genotype in codons 72-76.

  12. A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras.

    Science.gov (United States)

    Fontecha, Gustavo A; Sanchez, Ana L; Mendoza, Meisy; Banegas, Engels; Mejía-Torres, Rosa E

    2014-07-01

    Countries could use the monitoring of drug resistance in malaria parasites as an effective early warning system to develop the timely response mechanisms that are required to avert the further spread of malaria. Drug resistance surveillance is essential in areas where no drug resistance has been reported, especially if neighbouring countries have previously reported resistance. Here, we present the results of a four-year surveillance program based on the sequencing of the pfcrt gene of Plasmodium falciparum populations from endemic areas of Honduras. All isolates were susceptible to chloroquine, as revealed by the pfcrt "CVMNK" genotype in codons 72-76.

  13. Four Years of Real-Time GRB Followup by BOOTES-1B (2005–2008

    Directory of Open Access Journals (Sweden)

    Martin Jelínek

    2010-01-01

    Full Text Available Four years of BOOTES-1B GRB follow-up history are summarised for the first time in the form of a table. The successfully followed events are described case by case. Further, the data are used to show the GRB trigger rate in Spain on a per-year basis, resulting in an estimate of 18 triggers and about 51 hours of telescope time per year for real-time triggers. These numbers grow to about 22 triggers and 77 hours per year if we include also the GRBs observable within 2 hours after the trigger.

  14. Epilation for minor trachomatous trichiasis: four-year results of a randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Esmael Habtamu

    2015-03-01

    Full Text Available Trachomatous trichiasis (TT needs to be managed to reduce the risk of vision loss. The long-term impact of epilation (a common traditional practice of repeated plucking of lashes touching the eye in preventing visual impairment and corneal opacity from TT is unknown. We conducted a randomized controlled trial of epilation versus surgery for the management of minor TT (fewer than six lashes touching the eye in Ethiopia. Here we report the four-year outcome and the effect on vision and corneal opacity.1300 individuals with minor TT were recruited and randomly assigned to quality trichiasis surgery or repeated epilation using high quality epilation forceps by a trained person with good near vision. Participants were examined six-monthly for two-years, and then at four-years after randomisation. At two-years all epilation arm participants were offered free surgery. At four-years 1151 (88.5% were re-examined: 572 (88% and 579 (89% from epilation and surgery arms, respectively. At that time, 21.1% of the surgery arm participants had recurrent TT; 189/572 (33% of the epilation arm had received surgery, while 383 (67% declined surgery and had continued epilating ("epilation-only". Among the epilation-only group, 207 (54.1% fully controlled their TT, 166 (43.3% had minor TT and 10 (2.6% had major TT (>5 lashes. There were no differences between participants in the epilation-only, epilation-to-surgery and surgery arm participants in changes in visual acuity and corneal opacity between baseline and four-years.Most minor TT participants randomised to the epilation arm continued epilating and controlled their TT. Change in vision and corneal opacity was comparable between surgery and epilation-only participants. This suggests that good quality epilation with regular follow-up is a reasonable second-line alternative to surgery for minor TT for individuals who either decline surgery or do not have immediate access to surgical treatment.

  15. Introduction of structural aseismic research in China in recent four years

    Institute of Scientific and Technical Information of China (English)

    罗奇峰; 石春香; 曹炳政; 杨树龙; 熊华; 李仕栋

    2003-01-01

    The paper mainly summarized the developments on structural aseismic theory, aseismic analysis and design ofreinforced concrete structure, lifeline system, several another kinds of structures, site and structure foundation,structure mitigation and isolation of vibration in China in recent four years. This is the introduction of recent re-search results of Chinese professionals for international organizations and professionals. At the same time, itprovides numerous abstract materials for colleagues to realize the trend of the structural aseismic theory and re-search range needing more study.

  16. Pyridoxine neuropathy. A four-year electrophysiological and clinical follow-up of a severe case.

    Science.gov (United States)

    Santoro, L; Ragno, M; Nucciotti, R; Barbieri, F; Caruso, G

    1991-02-01

    In a 54-year-old male a severe sensory neuropathy was observed during treatment for pulmonary tuberculosis with isoniazid (400 mg/day) and pyridoxine (600 mg/day). Eight months after withdrawal from isoniazid the sensory symptomatology was still progressing, although muscle strength was never reduced. A sural nerve biopsy revealed marked loss of large myelinated fibres. Only when pyridoxine treatment was interrupted did a slow improvement begin. A clinical and electrophysiologic follow-up showed a very slow and still incomplete recovery after four years. The possibility of an unusual individual susceptibility to toxic effects of pyridoxine is considered.

  17. A FOUR-YEAR CHRONOLOGY WITH NATIONAL TEAM BOXING IN CANADA

    Directory of Open Access Journals (Sweden)

    Robert J. Schinke

    2007-10-01

    Full Text Available Applied sport psychologists tend to begin their consulting relationships with national teams having formalized skills, and often, limited contextual and sport- specific understanding. The present report overviews the first four years of a long-term consulting relationship one practitioner developed with the Canadian National Boxing Team. From the vantage of an applied sport psychology consultant, I overview how a limited consulting role expanded into increased responsibilities and opportunities. Suggestions are provided for the aspiring sport psychology consultant interested in working with athletes and coaches within the combative sport of elite amateur boxing

  18. Follow-up of preterm children: II. Growth and development at four years of age.

    Science.gov (United States)

    Forslund, M; Bjerre, I

    1990-11-01

    In a long-term prospective study, 46 unselected infants born before 35 completed weeks of gestation were compared with 26 full-term infants. At four years of age, 44 preterms and 25 full-terms were available to follow-up. The preterms were somewhat shorter in stature and lighter in weight than the full-terms but fell well within the normal range for Swedish children. Head circumference in the preterm group was significantly correlated to neurological development. Psychometric evaluation with Griffiths' mental developmental scale showed the preterms to fall within the normal range, though their performance was inferior to that of the full-terms. The greatest differences between the groups were in scores for the subscales eye and hand coordination, performance, and practical reasoning. There was no correlation within the preterm group between the test results and birthweight, gestational age, prenatal score, perinatal score, or parental social status or education. Language development was delayed among the preterms, more of whom required speech therapy. Visual and hearing disorders were more common among preterms than expected. Although they were all in good health, more preterms than full-terms needed hospital care during the first four years of life.

  19. Local Interstellar Hydrogen's Disappearance at 1 Au: Four Years of IBEX in the Rising Solar Cycle

    CERN Document Server

    Saul, Lukas; Fuselier, Stephen; Kubiak, Marzena; McComas, Dave; Möbius, Eberhard; Sokół, Justina; Rodríguez, Diego; Scheer, Juergen; Wurz, Peter

    2013-01-01

    NASA's Interstellar Boundary Explorer (IBEX) mission has recently opened a new window on the interstellar medium (ISM) by imaging neutral atoms. One "bright" feature in the sky is the interstellar wind flowing into the solar system. Composed of remnants of stellar explosions as well as primordial gas and plasma, the ISM is by no means uniform. The interaction of the local ISM with the solar wind shapes our heliospheric environment with hydrogen being the dominant component of the very local ISM. In this paper, we report on direct sampling of the neutral hydrogen of the local ISM over four years of IBEX observations. The hydrogen wind observed at 1 AU has decreased and nearly disappeared as the solar activity has increased over the last four years; the signal at 1 AU has dropped off in 2012 by a factor of ~8 to near background levels. The longitudinal offset has also increased with time presumably due to greater radiation pressure deflecting the interstellar wind. We present longitudinal and latitudinal arriva...

  20. Increasing resistance to quinolones: A four-year prospective study of urinary tract infection pathogens

    Directory of Open Access Journals (Sweden)

    Orhiosefe Omigie

    2009-08-01

    Full Text Available Orhiosefe Omigie, Lawrence Okoror, Patience Umolu, Gladys IkuuhDepartment of Microbiology, Ambrose Alli University, Ekpoma, NigeriaAbstract: A four-year prospective study was carried out to determine the incidence and rate of development of resistance by common urinary tract infection (UTI pathogens to quinolone antimicrobial agents. Results show that there is high intrinsic resistance to the quinolones among strains of Pseudomonas aeruginosa (43.4%, Escherichia coli (26.3%, and Proteus spp. (17.1%. Over four years, rising rates of resistance were observed in P. aeruginosa (14.6% increase, Staphylococcus aureus (9.8%, and E. coli (9.7%. The highest potency was exhibited by ciprofloxacin (91.2%, levofloxacin (89.2%, and moxifloxacin (85.1%, while there were high rates of resistance to nalidixic acid (51.7% and pefloxacin (29.0%. Coliforms, particularly E. coli (>45%, remain the most prevalent causative agents of UTI while females within the age range of 20–50 years were most vulnerable to UTI.Keywords: UTI, microorganisms, antibiotics, resistance

  1. A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

    Science.gov (United States)

    Melcer, Ted; Walker, Jay; Bhatnagar, Vibha; Richard, Erin; Sechriest, V Franklin; Galarneau, Michael

    2017-01-01

    Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107). Patient medical records were analyzed for four years postinjury. After adjusting for group differences, early amputation was generally associated with a lower or similar prevalence for adverse physical and psychological diagnoses (e.g., pain, osteoarthritis, posttraumatic stress disorder) versus late amputation and/or limb salvage. By contrast, early amputation was associated with an increased likelihood of osteoporosis during the first year postinjury. The prevalence of posttraumatic stress disorder increased for all patient groups over four years postinjury, particularly in the second year. The different clinical outcomes among combat extremity injured patients treated with early amputation, late amputation, or limb salvage highlight their different healthcare requirements. These findings can inform and optimize the specific treatment pathways that address the physical and psychological healthcare needs of such patients over time.

  2. Overweight among Four-Year-Old Children in Relation to Early Growth Characteristics and Socioeconomic Factors

    Directory of Open Access Journals (Sweden)

    Jörgen Thorn

    2010-01-01

    Full Text Available Objectives. To assess early growth characteristics and socioeconomic factors of children in relation to body mass index (BMI and presence of overweight among four-year-old children. Methods. Two Child Health Centres (CHC participated in the study. They were selected to obtain two populations of children featuring divergent socio-economic characteristics. Growth data registered at the CHCs from birth to the 4-year check-up were recovered. Overweight was defined by the BMI cut-offs established by IOTF. BMI values expressed as BMI standard deviation score (BMISDS were used for analysis. Results. At the 4-year check-up, the BMISDS and the proportion of children with overweight (including the obese were significantly higher in the district with lower socio-economic status. High BMI at birth and low socio-economic status of the population in the CHC-district were shown to be independent determinants for overweight and BMISDS at four years of age. Conclusions. More research is needed to understand the mechanisms and how intervention programs should be designed in order to prevent the development of overweight and obesity in children.

  3. A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage

    Science.gov (United States)

    Walker, Jay; Bhatnagar, Vibha; Richard, Erin; Sechriest, V. Franklin; Galarneau, Michael

    2017-01-01

    Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107). Patient medical records were analyzed for four years postinjury. After adjusting for group differences, early amputation was generally associated with a lower or similar prevalence for adverse physical and psychological diagnoses (e.g., pain, osteoarthritis, posttraumatic stress disorder) versus late amputation and/or limb salvage. By contrast, early amputation was associated with an increased likelihood of osteoporosis during the first year postinjury. The prevalence of posttraumatic stress disorder increased for all patient groups over four years postinjury, particularly in the second year. The different clinical outcomes among combat extremity injured patients treated with early amputation, late amputation, or limb salvage highlight their different healthcare requirements. These findings can inform and optimize the specific treatment pathways that address the physical and psychological healthcare needs of such patients over time. PMID:28122002

  4. Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study.

    Science.gov (United States)

    Lebranchu, Y; Thierry, A; Thervet, E; Büchler, M; Etienne, I; Westeel, P F; Hurault de Ligny, B; Moulin, B; Rérolle, J P; Frouget, T; Girardot-Seguin, S; Toupance, O

    2011-08-01

    Calcineurin inhibitor (CNI) withdrawal has been used as a strategy to improve renal allograft function. We previously reported that conversion from cyclosporine A (CsA) to sirolimus (SRL) 3 months after transplantation significantly improved renal function at 1 year. In the Postconcept trial, 77 patients in the SRL group and 85 in the CsA group were followed for 48 months. Renal function (Cockcroft and Gault) was significantly better at month 48 (M48) in the SRL group both in the intent-to-treat population (ITT): 62.6 mL/min/1.73 m(2) versus 57.1 mL/min/1.73 m(2) (p = 0.013) and in the on-treatment population (OT): 67.5 mL/min/1.73 m(2) versus 57.4 mL/min/1.73 m(2) (p = 0.002). Two biopsy proven acute rejection episodes occurred after M12 in each group. Graft and patient survival were comparable (graft survival: 97.4 vs. 100%; patient survival: 97.4 vs. 97.6%, respectively). The incidence of new-onset diabetes was numerically increased in the SRL group (7 vs. 2). In OT, three cancers occurred in the SRL group versus nine in the CsA group and mean proteinuria was increased in the SRL group (0.42 ± 0.44 vs. 0.26 ± 0.37; p = 0.018). In summary, the renal benefits associated with conversion of CsA to SRL, at 3 months posttransplantation, in combination with MMF were maintained for 4 years posttransplantation.

  5. Exploring the experiences of female students in introductory project-based engineering courses at two- and four-year institutions

    Science.gov (United States)

    Swan, Amy K.

    2011-12-01

    This qualitative study explored the experiential and contextual factors that shaped female students' pathways into introductory project-based engineering classes at two community colleges and one four-year institution, as well as female students' experiences within and outside of these classes. The study was framed by Social Cognitive Career Theory (SCCT) (Lent, Brown & Hackett, 1996) and Bronfenbrenner's (1979) ecological systems theory. Findings were based on analyses of data gathered through multiple methods: observations; individual interviews with female students; focus group interviews with project teams; and document collection. The findings of this study revealed that while positive experiences with math or science were a likely pre-cursor to engineering interest, experiential learning appeared to be a more powerful force in fostering students' engineering interest. Specifically, participants developed an interest in engineering through academic, professional, and extracurricular engineering- and design-related activities that familiarized them with the tasks and skills involved in engineering work and helped them develop a sense of selfefficacy with regard to this work. Interest and self-efficacy, in turn, played a role in students' postsecondary educational decision-making processes, as did contextual factors including families and finances. This study's findings also showed that participants' project teams were a critically important microsystem within participants' ecological environments. Within this sometimes "chilly" microsystem, female students negotiated intrateam processes, which were in some cases affected by gender norms. Intrateam processes that influenced female students' project-based learning experiences included: interpersonal dynamics; leadership; and division of labor. This study also identified several ways in which the lived experiences of participants at the community colleges were different from, or similar to, those of participants

  6. ACGT: advancing clinico-genomic trials on cancer - four years of experience.

    Science.gov (United States)

    Martin, Luis; Anguita, Alberto; Graf, Norbert; Tsiknakis, Manolis; Brochhausen, Mathias; Rüping, Stefan; Bucur, Anca; Sfakianakis, Stelios; Sengstag, Thierry; Buffa, Francesca; Stenzhorn, Holger

    2011-01-01

    The challenges regarding seamless integration of distributed, heterogeneous and multilevel data arising in the context of contemporary, post-genomic clinical trials cannot be effectively addressed with current methodologies. An urgent need exists to access data in a uniform manner, to share information among different clinical and research centers, and to store data in secure repositories assuring the privacy of patients. Advancing Clinico-Genomic Trials (ACGT) was a European Commission funded Integrated Project that aimed at providing tools and methods to enhance the efficiency of clinical trials in the -omics era. The project, now completed after four years of work, involved the development of both a set of methodological approaches as well as tools and services and its testing in the context of real-world clinico-genomic scenarios. This paper describes the main experiences using the ACGT platform and its tools within one such scenario and highlights the very promising results obtained.

  7. Photon Detection Efficiency Measurements of the VERITAS Cherenkov Telescope Photomultipliers after four Years of Operation

    CERN Document Server

    Gazda, Eliza; Otte, Nepomuk; Richards, Gregory

    2016-01-01

    The photon detection efficiency of two sets of R10560-100-20 superbialkali photomultiplier tubes from Hamamatsu were measured between 200 nm and 750 nm to quantify a possible degradation of the photocathode sensitivity after four years of operation in the cameras of the VERITAS Cherenkov telescopes. A sample of 20 photomultiplier tubes, which was removed from the telescopes was compared with a sample of 20 spare photomultiplier tubes, which had been kept in storage. It is found that the average photocathode sensitivity marginally increased below 300 nm and dropped by 10% to 30% above 500 nm. The average photocathode sensitivity folded with the Cherenkov spectrum emitted by particles in air showers, however, reveals a consistent detection yield of 18.9+/-0.2% and 19.1+/-0.2% for the sample removed from the telescope and the spare sample, respectively.

  8. The Nuclear Organization and Management Analysis Concept methodology: Four years later

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Shurberg, D.A.; Barriere, M.T.; Hall, R.E.

    1992-08-01

    The Nuclear Organization and Management Analysis Concept was first presented at the IEEE Human Factors meeting in Monterey in 1988. In the four years since that paper, the concept and its associated methodology has been demonstrated at two commercial nuclear power plants (NPP) and one fossil power plant. In addition, applications of some of the methods have been utilized in other types of organizations, and products are being developed from the insights obtained using the concept for various organization and management activities. This paper will focus on the insights and results obtained from the two demonstration studies at the commercial NPPs. The results emphasize the utility of the methodology and the comparability of the results from the two organizations.

  9. The Nuclear Organization and Management Analysis Concept methodology: Four years later

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Shurberg, D.A.; Barriere, M.T.; Hall, R.E.

    1992-01-01

    The Nuclear Organization and Management Analysis Concept was first presented at the IEEE Human Factors meeting in Monterey in 1988. In the four years since that paper, the concept and its associated methodology has been demonstrated at two commercial nuclear power plants (NPP) and one fossil power plant. In addition, applications of some of the methods have been utilized in other types of organizations, and products are being developed from the insights obtained using the concept for various organization and management activities. This paper will focus on the insights and results obtained from the two demonstration studies at the commercial NPPs. The results emphasize the utility of the methodology and the comparability of the results from the two organizations.

  10. Liver Metastasis Four Years after Whipple's Resection for Solid-Pseudopapillary Tumor of the Pancreas

    Directory of Open Access Journals (Sweden)

    Srikrishna Nagri

    2007-03-01

    Full Text Available Context Solid-pseudopapillary tumor of the pancreas is a rare tumor which usually affects young females in their second and third decade of life. Metastasis is very rare after a resection of curative intent. Case report We report a case of a 65-yearold white female who presented with metastasis to the liver four years after Whipple’s resection for a solid-pseudopapillary tumor of the pancreas. Conclusions Solid-pseudopapillary tumors of the pancreas can present with metastasis a long time after resection of the primary tumor. Long term close follow up of these patients should be done. The survival rate even after liver metastasis is good.

  11. Four-Year-Olds Use a Mixture of Spatial Reference Frames.

    Directory of Open Access Journals (Sweden)

    James Negen

    Full Text Available Keeping track of unseen objects is an important spatial skill. In order to do this, people must situate the object in terms of different frames of reference, including body position (egocentric frame of reference, landmarks in the surrounding environment (extrinsic frame reference, or other attached features (intrinsic frame of reference. Nardini et al. hid a toy in one of 12 cups in front of children, turned the array when they were not looking, and then asked them to point to the cup with the toy. This forced children to use the intrinsic frame (information about the array of cups to locate the hidden toy. Three-year-olds made systematic errors by using the wrong frame of reference, 4-year-olds were at chance, and only 5- and 6-year-olds were successful. Can we better understand the developmental change that takes place at four years? This paper uses a modelling approach to re-examine the data and distinguish three possible strategies that could lead to the previous results at four years: (1 Children were choosing cups randomly, (2 Children were pointing between the egocentric/extrinsic-cued location and the correct target, and (3 Children were pointing near the egocentric/extrinsic-cued location on some trials and near the target on the rest. Results heavily favor the last possibility: 4-year-olds were not just guessing or trying to combine the available frames of reference. They were using the intrinsic frame on some trials, but not doing so consistently. These insights suggest that accounts of improving spatial performance at 4 years need to explain why there is a mixture of responses. Further application of the selected model also suggests that children become both more reliant on the correct frame and more accurate with any chosen frame as they mature.

  12. Four-Year-Olds Use a Mixture of Spatial Reference Frames.

    Science.gov (United States)

    Negen, James; Nardini, Marko

    2015-01-01

    Keeping track of unseen objects is an important spatial skill. In order to do this, people must situate the object in terms of different frames of reference, including body position (egocentric frame of reference), landmarks in the surrounding environment (extrinsic frame reference), or other attached features (intrinsic frame of reference). Nardini et al. hid a toy in one of 12 cups in front of children, turned the array when they were not looking, and then asked them to point to the cup with the toy. This forced children to use the intrinsic frame (information about the array of cups) to locate the hidden toy. Three-year-olds made systematic errors by using the wrong frame of reference, 4-year-olds were at chance, and only 5- and 6-year-olds were successful. Can we better understand the developmental change that takes place at four years? This paper uses a modelling approach to re-examine the data and distinguish three possible strategies that could lead to the previous results at four years: (1) Children were choosing cups randomly, (2) Children were pointing between the egocentric/extrinsic-cued location and the correct target, and (3) Children were pointing near the egocentric/extrinsic-cued location on some trials and near the target on the rest. Results heavily favor the last possibility: 4-year-olds were not just guessing or trying to combine the available frames of reference. They were using the intrinsic frame on some trials, but not doing so consistently. These insights suggest that accounts of improving spatial performance at 4 years need to explain why there is a mixture of responses. Further application of the selected model also suggests that children become both more reliant on the correct frame and more accurate with any chosen frame as they mature.

  13. Bobath or motor relearning programme? A follow-up one and four years post stroke.

    Science.gov (United States)

    Langhammer, Birgitta; Stanghelle, Johan K

    2003-11-01

    The purpose of this follow-up one and four years post stroke was to find out whether the initial physiotherapy approach had had any long-term effects on mortality, motor function, postural control, activities of daily living, life quality, follow-up from community services and living conditions. A randomized controlled trial of first time ever stroke patients. Group 1 (n = 33) and group 2 (n = 28) had initial physiotherapy according to the Motor Relearning Programme and Bobath, respectively. The Motor Assessment Scale (MAS), the Sødring Motor Evaluation Scale (SMES), the Barthel ADL Index, the Nottingham Health Profile (NHP) and Berg Balance Scale were used. The following parameters were also registered: incidence of new strokes, other diseases, use of assistive devices, the patient's accommodation and use of services from the community. The mortality rates were similar in the two groups. In both groups the motor function, postural control and ADL had decreased rapidly, leaving many of the patients dependent and with a high risk of falling. Life quality had increased compared to the acute stage, but was still low in comparison with healthy persons. Patients in both groups lived at home, but were dependent on help from relatives and community services. Physiotherapy as follow-up service was seldom used. The initial physiotherapy approach did not seem to have a major influence on the patients' ability to cope in the long-term. This follow-up at one and four years post stroke showed no major influence of two different initial physiotherapy regimens on long-term function. The study confirmed a rapid deterioration of ADL and motor function and an increased dependence on relatives. The study reveals a gap between the intense treatment in the acute phase and little or no follow-up of physiotherapy treatment or other rehabilitation activities later.

  14. Atypical hemolytic uremic syndrome diagnosed four years after ABO-incompatible kidney transplantation.

    Science.gov (United States)

    Kawaguchi, Keiko; Kawanishi, Kunio; Sato, Masayo; Itabashi, Mitsuyo; Fujii, Akiko; Kanetsuna, Yukiko; Huchinoue, Shouhei; Ohashi, Ryuji; Koike, Junki; Honda, Kazuho; Nagashima, Yoji; Nitta, Kosaku

    2015-07-01

    Atypical hemolytic uremic syndrome (aHUS) in allograft kidney transplantation is caused by various factors including rejection, infection, and immunosuppressive drugs. We present a case of a 32 year old woman with aHUS four years after an ABO-incompatible kidney transplantation from a living relative. The primary cause of end-stage renal disease was unknown; however, IgA nephropathy (IgAN) was suspected from her clinical course. She underwent pre-emptive kidney transplantation from her 60 year old mother. The allograft preserved good renal function [serum creatinine (sCr) level 110-130 μmol/L] until a sudden attack of abdominal pain four years after transplant, with acute renal failure (sCr level, 385.3 μmol/L), decreasing platelet count, and hemolytic anemia with schizocytes. On allograft biopsy, there was thrombotic microangiopathy in the glomeruli, with a cellular crescent formation and mesangial IgA and C3 deposition. Microvascular inflammation, such as glomerulitis, peritubular capillaritis, and arteriole endarteritis were also detected. A disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13 (ADAMTS13) did not decrease and Shiga toxin was not detected. Donor-specific antibodies or autoantibodies, including anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane (anti-GBM) antibody, were negative. The patient was diagnosed with aHUS and received three sessions of plasmapheresis and methylprednisolone pulse therapy, followed by oral methylprednisolone (0.25-0.5 mg/kg) instead of tacrolimus. She temporarily required hemodialysis (sCr level, 658.3 μmol/L). Thereafter, her sCr level improved to 284.5 μmol/L without dialysis therapy. This case is clinically considered as aHUS after kidney transplantation, associated with various factors, including rejection, glomerulonephritis, and toxicity from drugs such as tacrolimus.

  15. Variation across Hispanic Immigrant Generations in Parent Social Capital, College-Aligned Actions, and Four-Year College Enrollment

    Science.gov (United States)

    Ryan, Sarah; Ream, Robert K.

    2016-01-01

    Not beginning college at a four-year institution has been demonstrated as one key obstacle to equitable rates of bachelor's degree attainment among Hispanic individuals in the United States. Drawing on nationally representative longitudinal data and social capital theory, this research investigates the process of four-year college enrollment among…

  16. Dietary Fat Intake and Exercise among Two- and Four-Year College Students: Differences in Behavior and Psychosocial Factors

    Science.gov (United States)

    Berg, Carla J.; An, Lawrence C.; Ahluwalia, Jasjit S.

    2013-01-01

    Given the demographic differences among two-year colleges and four-year universities and the relatively limited access to health education and campus-based health resources, this study compares the frequency of limiting dietary fat intake and exercising among two- and four-year college students. A total of 2,265 undergraduate students aged 18-25…

  17. The Educational Attainment of Chicago Public Schools Students: A Focus on Four-Year College Degrees. Research Brief

    Science.gov (United States)

    Healey, Kaleen; Nagaoka, Jenny; Michelman, Valerie

    2014-01-01

    A four-year college degree increases a student's employment prospects and earning potential. Given this importance, it is not surprising that 75 percent of Chicago Public Schools (CPS) high school students aspire to obtain at least a four-year college degree. Yet, prior research showed that few achieved this goal: a 2006 University of Chicago…

  18. Cause of Sudden Cardiac Deaths on Autopsy Findings; a Four-Year Report

    Directory of Open Access Journals (Sweden)

    Dinesh Rao

    2014-03-01

    Full Text Available Introduction: Incidence of sudden cardiac death (SCD has been steadily increasing all over the world. While knowing the cause of SCD is one of the favorites of the physicians involved with these cases, it is very difficult and challenging task for the forensic physician. The present report is a prospective study regarding cause of SCDs on autopsy examination in four-year period, Bangalore, India. Methods: The present prospective study is based on autopsy observations, carried out for four-year period from 2008 to 2011, and analyzed for cause of SCDs. The cases were chosen as per the definition of sudden death and autopsied. The material was divided into natural and unnatural groups. Finally, on histopathology, gross examination, hospital details, circumstantial, and police reports the cause of death was inferred. Results: A total of 2449 autopsy was conducted of which 204 cases were due to SCD. The highest SCDs were reported in 50-60 years age group (62.24%; n-127, followed closely by the age group 60-69 (28.43%; n-58. Male to female ratio was around 10:1. The maximum number of deaths (n=78 was within few hours (6 hours after the onset of signs and symptoms. In 24 (11.8% cases major narrowing was noted in both the main coronaries, in 87 (42.6% cases in the left anterior descending coronary artery (LAD, and in 18 (51.5% cases in the right coronary artery (RCA. The major cardiac pathology resulting in sudden death was coronary artery disease (n-116; 56.86% and myocardial infarction (n-104; 50.9%. most of the SCDs occurred in the place of residence (n-80; 39.2% followed closely by death in hospital (n-49; 24.01%. Conclusion: Coronary occlusion was the major contributory cause of sudden death with cardiac origin and the highest number of deaths were reported in the age 50-59 years with male to female ratio of 10:1. 

  19. Delineation and Scale Effect of Precision Agriculture Management Zones Using Yield Monitor Data Over Four Years

    Institute of Scientific and Technical Information of China (English)

    LI Xiang; PAN Yu-chun; GE Zhong-qiang; ZHAO Chun-jiang

    2007-01-01

    In this study, precision agriculture management zones were delineated using yield data over four years from the combine harvester equipped with yield monitor and DGPS receiver. Relative yields measured during each year were interpolated to 4 m2 grid size using ordinary kriging. The resultant interpolated yield maps were averaged across years to create a map of the mean relative yield, which was then used for cluster analysis. The mean yield map of post-classification was processed by applying majority filtering with window sizes that were equivalent to the grid sizes of 12, 20, 28, 36, 44, 52 and 60 m. The scale effect of management zones was evaluated using relative variance reduction, test of significant differences of the means of yield zones, spatial fragmentation, and spatial agreement. The results showed that the post-classification majority filtering (PCMF) eliminated lots of isolated cells or patches caused by random variation while preserving yield means, high variance reduction, general yield patterns, and high spatial agreement. The zoned result can be used as yield goal map for preplant or in-season fertilizer recommendation in precision agriculture.

  20. Space and ground segment performance of the FORMOSAT-3/COSMIC mission: four years in orbit

    Directory of Open Access Journals (Sweden)

    C.-J. Fong

    2011-01-01

    Full Text Available The FORMOSAT-3/COSMIC (Constellation Observing System for Meteorology, Ionosphere, and Climate mission consisting of six Low-Earth-Orbit (LEO satellites is the world's first demonstration constellation using radio occultation signals from Global Positioning System (GPS satellites. The radio occultation signals are retrieved in near real-time for global weather/climate monitoring, numerical weather prediction, and space weather research. The mission has processed on average 1400 to 1800 high-quality atmospheric sounding profiles per day. The atmospheric radio occultation soundings data are assimilated into operational numerical weather prediction models for global weather prediction, including typhoon/hurricane/cyclone forecasts. The radio occultation data has shown a positive impact on weather predictions at many national weather forecast centers. A proposed follow-on mission transitions the program from the current experimental research system to a significantly improved real-time operational system, which will reliably provide 8000 radio occultation soundings per day. The follow-on mission as planned will consist of 12 satellites with a data latency of 45 min, which will provide greatly enhanced opportunities for operational forecasts and scientific research. This paper will address the FORMOSAT-3/COSMIC system and mission overview, the spacecraft and ground system performance after four years in orbit, the lessons learned from the encountered technical challenges and observations, and the expected design improvements for the new spacecraft and ground system.

  1. The Western Kentucky University Blazar Monitoring Program: The First Four Years

    Science.gov (United States)

    Walters, R.; Barnaby, D.; Carini, M.

    2006-07-01

    In 2000, we began a blazar monitoring program utilizing the 0.6m telescope of the Bell Observatory at Western Kentucky University. We chose a sample of objects from across the αro - αox plane in order to characterize the variability characteristics of HBLs, IBLs and LBLs. The most rapid timescale variations, known as microvariability, provide information on differences in jet characteristics and observations of microvariability at different colors provides insight into the nature of the particle acceleration mechanisms in the different subclasses of blazars during different activity levels. On longer timescales (days to weeks) multiwavelength observations (via our participation in WEBT campaigns, VERITAS campaigns, etc) can be used to confront models describing the origin of the seed photons responsible for the observed high energy emission in these objects. Through our ability to obtain well sampled light curves, we will, at the longest timescales (weeks to decades), establish the differences in the variability properties between different sub-classes. We present here the results of the first fours years of this program.

  2. Evaluation of a four year intervention to reduce musculoskeletal hazards among berry growers.

    Science.gov (United States)

    Chapman, Larry J; Newenhouse, Astrid C; Pereira, Kathryn M; Karsh, Ben-Tzion; Meyer, Robert M; Brunette, Christopher M; Ehlers, Janet J

    2008-01-01

    Fresh market berry production workers are exposed to physical risk factors for musculoskeletal injury. We disseminated information through trade publications and other sources to berry managers in seven U.S. states about five prevention through design practices that were both safer and more profitable than traditional methods. We administered mail evaluation questionnaires prior to the intervention and after each of four intervention years to rolling, independent U.S. samples and to comparison New Zealand berry farm manager samples after years one through three. U.S. manager self-reports of reading trade publication information increased compared to baseline values for two of five practices and self-reported awareness increased for four of five practices. There were no increases in adoption. More U.S. than New Zealand managers reported getting information about two practices from trade publications and about four practices from public events. No U.S. versus New Zealand differences were observed in reported awareness or adoption for any practice. This study showed that even a modest campaign can build awareness of safer practices fairly quickly in three to four years among small agricultural firms but that increasing adoption apparently requires more time. Widespread adoption of safer practices could help keep operators in business longer as they age by reducing the workload and musculoskeletal strain associated with labor intensive crop production for them and their workforce. Adoption of practices that also improve profits, like the five practices featured in this study, could also help managers stay in business.

  3. Four-year-old Cantonese-speaking children's online processing of relative clauses: a permutation analysis.

    Science.gov (United States)

    Chan, Angel; Yang, Wenchun; Chang, Franklin; Kidd, Evan

    2017-06-13

    We report on an eye-tracking study that investigated four-year-old Cantonese-speaking children's online processing of subject and object relative clauses (RCs). Children's eye-movements were recorded as they listened to RC structures identifying a unique referent (e.g. "Can you pick up the horse that pushed the pig?"). Two RC types, classifier (CL) and ge3 RCs, were tested in a between-participants design. The two RC types differ in their syntactic analyses and frequency of occurrence, providing an important point of comparison for theories of RC acquisition and processing. A permutation analysis showed that the two structures were processed differently: CL RCs showed a significant object-over-subject advantage, whereas ge3 RCs showed the opposite effect. This study shows that children can have different preferences even for two very similar RC structures within the same language, suggesting that syntactic processing preferences are shaped by the unique features of particular constructions both within and across different linguistic typologies.

  4. Spectroscopy of High-Redshift Supernovae from the ESSENCE Project: The First Four Years

    CERN Document Server

    Foley, R J; Blondin, S; Chornock, R; Silverman, J M; Challis, P; Clocchiatti, A; Filippenko, A V; Kirshner, R P; Leibundgut, B; Sollerman, J; Spyromilio, J; Tonry, J L; Davis, T M; Garnavich, P M; Jha, S W; Krisciunas, K; Li, W; Pignata, G; Rest, A; Riess, A G; Schmidt, B P; Smith, R C; Stubbs, C W; Tucker, B E; Wood-Vasey, W M

    2008-01-01

    We present the results of spectroscopic observations from the ESSENCE high-redshift supernova (SN) survey during its first four years of operation. This sample includes spectra of all SNe Ia whose light curves were presented by Miknaitis et al. (2007) and used in the cosmological analyses of Davis et al. (2007) and Wood-Vasey et al. (2007). The sample represents 273 hours of spectroscopic observations with 6.5 - 10-m-class telescopes of objects detected and selected for spectroscopy by the ESSENCE team. We present 174 spectra of 156 objects. Combining this sample with that of Matheson et al. (2005), we have a total sample of 329 spectra of 274 objects. From this, we are able to spectroscopically classify 118 Type Ia SNe. As the survey has matured, the efficiency of classifying SNe Ia has remained constant while we have observed both higher-redshift SNe Ia and SNe Ia farther from maximum brightness. Examining the subsample of SNe Ia with host-galaxy redshifts shows that redshifts derived from only the SN Ia sp...

  5. Who Benefits From Four-Year Higher Education in Turkey? A Case Study of Law School

    Directory of Open Access Journals (Sweden)

    Filiz GÖLPEK

    2013-01-01

    Full Text Available In many countries, a higher education system which is based on welfare state practices prevails. In this system, the services are substantially provided by the state free of charge or at quite low prices. Since the services are financed by taxes, additional sources cannot be provided; and because of the fact that it doesn't entail a real cost benefit comparison by the users, it leads to inefficiency. From the early 80s on, there has been a tendency towards the marketing mechanisms in the provision of many public services such as education due to both strong theoretical and empirical reason, and the restrictions in public financing. Together with this tendency, the question of who benefits from education services is tried to be answered in order to discuss the stimulation of activities and additional resources on a reasonable base. The aim of this study is to determine whether it is the individual or the society who benefits from this public service at the higher education level by calculating private and social return rates through internal return rate technique which is one of the cost benefit analysis method. Findings from calculations have shown that the individual gains more than the society after a four-year university education.

  6. The Fermi GBM Gamma-Ray Burst Spectral Catalog: Four Years Of Data

    CERN Document Server

    Gruber, David; von Ahlefeld, Victoria Weller; Bhat, P Narayana; Bissaldi, Elisabetta; Briggs, Michael S; Byrne, Dave; Cleveland, William H; Connaughton, Valerie; Fishman, Gerald J; Fitzpatrick, Gerard; Foley, Suzanne; Gibby, Melissa; Giles, Misty M; Greiner, Jochen; Guiriec, Sylvain; van der Horst, Alexander J; von Kienlin, Andreas; Kouveliotou, Chryssa; Layden, Emily; Lin, Lin; Meegan, Charles A; McGlynn, Sinéad; Paciesas, William S; Pelassa, Véronique; Preece, Robert D; Rau, Arne; Wilson-Hodge, Colleen A; Xiong, Shaolin; Yu, Hoi-Fung

    2014-01-01

    In this catalog we present the updated set of spectral analyses of GRBs detected by the Fermi Gamma-Ray Burst Monitor (GBM) during its first four years of operation. It contains two types of spectra, time-integrated spectral fits and spectral fits at the brightest time bin, from 943 triggered GRBs. Four different spectral models were fitted to the data, resulting in a compendium of more than 7500 spectra. The analysis was performed similarly, but not identically to Goldstein et al. 2012. All 487 GRBs from the first two years have been re-fitted using the same methodology as that of the 456 GRBs in years three and four. We describe, in detail, our procedure and criteria for the analysis, and present the results in the form of parameter distributions both for the observer-frame and rest-frame quantities. The data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center (HEASARC).

  7. The rotational state of Mercury after four years of MESSENGER observations

    Science.gov (United States)

    Stark, Alexander; Oberst, Jürgen; Preusker, Frank; Hussmann, Hauke

    2017-04-01

    We measured the rotational state of Mercury with orbital data from NASA's MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft. We use accurate co-registration of digital terrain models from stereo images (stereo DTMs) and laser altimeter data to measure the orientation of the rotation axis, the libration amplitude and the mean rotation rate with improved precision. In contrast to our previous study, we use the full four years of near-continuous Mercury Laser Altimeter (MLA) observations and stereo DTMs with a higher spatial coverage. We confirm a large libration amplitude and a mean rotation rate which is significantly higher than the assumed resonant rotation rate based on a perfect 3:2 spin orbit resonance. The estimated orientation of the rotation axis is consistent with the assumption that Mercury occupies a Cassini state. We compare our estimates with values based on Earth-based observations and MESSENGER radio science. Our results confirm that Mercury possesses a liquid outer core and we discuss further implications of our estimates on the interior structure of the planet.

  8. FOUR-YEAR-OLD NAMSAN TUNNEL CONGESTION PRICING SCHEME IN SEOUL

    Directory of Open Access Journals (Sweden)

    Bongsoo SON, Ph. D.

    2002-01-01

    Full Text Available The purpose of this paper is to evaluate the effectiveness of the congestion pricing scheme at Namsan #1 and #3 tunnels in downtown Seoul four years after its implementation. The effectiveness of the scheme was measured by the changes of various traffic impacts. The traffic volume of the two tunnels was reduced by up to 25% for the first month. After that time, the traffic volume started to increase again and then exceeded the previous volume level. However, average travel speed of the two tunnel corridors improved by up to 74%. The overall traffic volume of the four alternative routes was increased; nevertheless, their average travel speed increased as well. The number of carpool vehicles occupied by 3 or more persons including the driver during the peak periods was remarkably increased. Before the congestion fee charging, toll-charged vehicles amounted to 68.5% of the total traffic volume of the two tunnels, and then the share dropped to 29% afterwards. The empirical analysis results for the effectiveness of the congestion pricing scheme are very promising.

  9. THE INFORMATION-COMMUNICATION TECHNOLOGY IN THE HOME ENVIRONMENT OF FOUR-YEAR-OLD PRESCHOOL CHILDREN

    Directory of Open Access Journals (Sweden)

    Jurka Lepičnik Vodopivec

    2014-01-01

    Full Text Available Today, preschool children live in an era of information-communication technologies (ICT. There exist various definitions of ICT. For the purposes of our research we thus used a broader definition of ICT, which stretches beyond mobiles and computers, and includes a variety of everyday technologies. Children already encounter them in their family environment. We wanted to find out which ICT children use the most, how they access them and if ICT has any influence on their development. Our sample consisted of 130 parents of four-year-old children who visit kindergarten. We were interested in the adults' – parents' influence and in the influence of the children’s gender on the access to and usage of ICT. We similarly wanted to know if these are influenced by the toy industry market and family values. A part of the research is also dedicated to the ICT’s influence on the perception of childhood and a plausible occurrence of the digital divide.

  10. The Impact of Impulsivity on Weight Loss Four Years after Bariatric Surgery

    Directory of Open Access Journals (Sweden)

    Kathrin Schag

    2016-11-01

    Full Text Available Bariatric surgery has serious implications on metabolic health. The reasons for a failure of bariatric surgery, i.e., limited weight loss, are multifactorial and include psychological factors. We established a theoretical model of how impulsivity is related to weight loss outcome. We propose that depressive symptoms act as a mediator between impulsivity and pathological eating behavior, and that pathological eating behavior has a direct impact on weight loss outcome. We calculated excessive weight loss (%EWL and assessed self-reported impulsivity (using the Baratt Impulsiveness Scale (BIS-15 total score, depressive symptoms (the Patient Health Questionnaire (PHQ-9 score, and pathological eating behavior (the Eating Disorder Inventory 2 (EDI-2 total score in 65 patients four years after laparoscopic sleeve gastrectomy. Regression and mediation analyses were computed to validate the theoretical model. The BIS-15, PHQ-9, and EDI-2 have medium to high correlations between each other, and EDI-2 correlated with %EWL. The mediation analysis yielded that the PHQ-9 represents a significant mediator between BIS-15 and EDI-2. The regression model between EDI-2 and %EWL was also significant. These results support our theoretical model, i.e., suggest that impulsivity has an indirect impact on weight loss outcome after bariatric surgery, mediated by depression and transferred through pathological eating behavior. Thus, the underlying psychological factors should be addressed in post-operative care to optimize weight loss outcome.

  11. The Effects of Inquiry-Based Integrated Information Literacy Instruction: Four-Year Trends

    Directory of Open Access Journals (Sweden)

    Lin Ching Chen

    2014-07-01

    Full Text Available The purpose of this study was to examine the effects of four-year integrated information literacy instruction via a framework of inquiry-based learning on elementary students’ memory and comprehension. Moderating factors of students’ academic achievement was another focus of this study. The subjects were 72 students who have participated in this study since they entered an elementary school in Chiayi district. This elementary school adopted the integrated information literacy instruction, designed by the researchers and elementary school teachers, and integrated it into various subject matters via a framework of inquiry-based learning, such as Super 3 and Big6 models. A series of inquiry-based integrated information literacy instruction has been implemented since the second semester of the subjects’ first grade. A total of seven inquiry learning projects has been implemented from grade one through grade four. Fourteen instruments were used as pretests and posttests to assess students’ factual recall and conceptual understanding of subject contents in different projects. The results showed that inquiry-based integrated information literacy instruction couldhelp students memorize facts and comprehend concepts of subject contents. Regardless ofacademic achievements, if students would like to devote their efforts to inquiry processes, their memory and comprehension of subject contents improvedeffectively. However, students of low-academic achievement might need more time to be familiar with the inquiry-based learning strategy.

  12. [Platelet transfusion and allergic transfusion reactions: experiences at Lille Hospital over a four year period].

    Science.gov (United States)

    Wibaut, B; Vannier, V; Renom, P; Goudemand, J

    2000-04-01

    Among the immediate transfusion reactions caused by the utilization of blood products, those suggesting immuno-allergic mechanisms posed problems for frequency, gravity, laboratory diagnosis and safety. We report here the Lille Hospital's experience over a four-year period concerning these manifestations after platelet concentrate transfusion. Eight hundred and fifty-two immediate transfusion reactions have been declared, of which 230 were allergic, which appeared in 181 patients (27%). Among the most frequent clinical signs, rash was often described (158 cases: 68.7%); less frequent were respiratory problems such as dyspnea (34 cases: 14.8%) and hypotensive reactions (18 cases: 7.8%). Seven patients presented severe reactions (3%). Twenty percent of them presented multiple allergic reactions and in 43.2%, the recurrence was more serious than the initial problem in spite of preventive medication; the use of washed blood components was necessary. The age of platelet concentrates does not appear to play a part in provoking these events (67% of platelet concentrates had been collected within four days). These allergic transfusion reactions posed problems for those who prescribe medication, because they are frequent, sometimes serious, can recur and at present, the proposed medication prevention is not always efficient.

  13. THE FERMI GBM GAMMA-RAY BURST SPECTRAL CATALOG: FOUR YEARS OF DATA

    Energy Technology Data Exchange (ETDEWEB)

    Gruber, David; Von Ahlefeld, Victoria Weller; Diehl, Roland; Greiner, Jochen; Von Kienlin, Andreas [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Goldstein, Adam; Bhat, P. Narayana; Briggs, Michael S.; Connaughton, Valerie [University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Bissaldi, Elisabetta [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, I-34127 Trieste (Italy); Byrne, Dave; Fitzpatrick, Gerard; Foley, Suzanne [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Cleveland, William H. [Universities Space Research Association, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Fishman, Gerald J.; Kouveliotou, Chryssa [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gibby, Melissa; Giles, Misty M. [Jacobs Technology, Inc., Huntsville, AL (United States); Guiriec, Sylvain [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Van der Horst, Alexander J. [Astronomical Institute, University of Amsterdam, Science Park 904, 1098 XH Amsterdam (Netherlands); and others

    2014-03-01

    In this catalog we present the updated set of spectral analyses of gamma-ray bursts (GRBs) detected by the Fermi Gamma-Ray Burst Monitor during its first four years of operation. It contains two types of spectra, time-integrated spectral fits and spectral fits at the brightest time bin, from 943 triggered GRBs. Four different spectral models were fitted to the data, resulting in a compendium of more than 7500 spectra. The analysis was performed similarly but not identically to Goldstein et al. All 487 GRBs from the first two years have been re-fitted using the same methodology as that of the 456 GRBs in years three and four. We describe, in detail, our procedure and criteria for the analysis and present the results in the form of parameter distributions both for the observer-frame and rest-frame quantities. The data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center.

  14. A four-year, systems-wide intervention promoting interprofessional collaboration

    Directory of Open Access Journals (Sweden)

    Braithwaite Jeffrey

    2012-04-01

    Full Text Available Abstract Background A four-year action research study was conducted across the Australian Capital Territory health system to strengthen interprofessional collaboration (IPC though multiple intervention activities. Methods We developed 272 substantial IPC intervention activities involving 2,407 face-to-face encounters with health system personnel. Staff attitudes toward IPC were surveyed yearly using Heinemann et al's Attitudes toward Health Care Teams and Parsell and Bligh's Readiness for Interprofessional Learning scales (RIPLS. At study's end staff assessed whether project goals were achieved. Results Of the improvement projects, 76 exhibited progress, and 57 made considerable gains in IPC. Educational workshops and feedback sessions were well received and stimulated interprofessional activities. Over time staff scores on Heinemann's Quality of Interprofessional Care subscale did not change significantly and scores on the Doctor Centrality subscale increased, contrary to predictions. Scores on the RIPLS subscales of Teamwork & Collaboration and Professional Identity did not alter. On average for the assessment items 33% of staff agreed that goals had been achieved, 10% disagreed, and 57% checked neutral. There was most agreement that the study had resulted in increased sharing of knowledge between professions and improved quality of patient care, and least agreement that between-professional rivalries had lessened and communication and trust between professions improved. Conclusions Our longitudinal interventional study of IPC involving multiple activities supporting increased IPC achieved many project-specific goals. However, improvements in attitudes over time were not demonstrated and neutral assessments predominated, highlighting the difficulties faced by studies targeting change at the systems level and over extended periods.

  15. The First Four Year's of Orthoimages from NEON's Airborne Observation Platform

    Science.gov (United States)

    Adler, J.; Gallery, W. O.

    2016-12-01

    The National Ecological Observatory Network (NEON), funded by the National Science Foundation (NSF), has been collecting orthorectified images in conjunction with lidar and spectrometer data for the past four years. The NEON project breaks up the United States into 20 regional areas from Puerto Rico to the North Slope of Alaska, with each region (Domain) typically having three specific sites of interest. Each site spans between 100km2 - 720km2 in area. Currently there are over 125,000 orthorectified images online from 6 Domains for the public and scientific community to freely download. These images are expected to assist researchers in many areas including vegetation cover, dominant vegetation type, and environmental change detection. In 2016 the NEON Airborne Observation Platform (AOP) group has collected digital imagery at 8.5 cm resolution over approximately 30 sites, for a total of 60,000 orthoimages. This presentation details the current status of the surveys conducted to date, and describes the scientific details of how NEON publishes Level 1 and Level 3 products. In particular, the onboard lidar system's contribution to the orthorectification process is outlined, in addition to the routines utilized for correcting white balance and exposure. Additionally, key flight parameters needed to produce NEON's complementary data of multi-sensor (camera/lidar/spectrometer) instruments are discussed. Problems with validating the orthoimages with the coarser resolution lidar system are addressed, to include the utilization of ground-truth locations. Lastly, methods to access NEON's publically available 10cm resolution orthoimages (in both individual image format, and in 1km by 1km tiles) are presented. A brief overview of the 2017 field season's nine new sites completes the presentation.

  16. A four-year cardiovascular risk score for type 2 diabetic inpatients

    Directory of Open Access Journals (Sweden)

    Dolores Ramírez-Prado

    2015-06-01

    Full Text Available As cardiovascular risk tables currently in use were constructed using data from the general population, the cardiovascular risk of patients admitted via the hospital emergency department may be underestimated. Accordingly, we constructed a predictive model for the appearance of cardiovascular diseases in patients with type 2 diabetes admitted via the emergency department. We undertook a four-year follow-up of a cohort of 112 adult patients with type 2 diabetes admitted via the emergency department for any cause except patients admitted with acute myocardial infarction, stroke, cancer, or a palliative status. The sample was selected randomly between 2010 and 2012. The primary outcome was time to cardiovascular disease. Other variables (at baseline were gender, age, heart failure, renal failure, depression, asthma/chronic obstructive pulmonary disease, hypertension, dyslipidaemia, insulin, smoking, admission for cardiovascular causes, pills per day, walking habit, fasting blood glucose and creatinine. A cardiovascular risk table was constructed based on the score to estimate the likelihood of cardiovascular disease. Risk groups were established and the c-statistic was calculated. Over a mean follow-up of 2.31 years, 39 patients had cardiovascular disease (34.8%, 95% CI [26.0–43.6%]. Predictive factors were gender, age, hypertension, renal failure, insulin, admission due to cardiovascular reasons and walking habit. The c-statistic was 0.734 (standard error: 0.049. After validation, this study will provide a tool for the primary health care services to enable the short-term prediction of cardiovascular disease after hospital discharge in patients with type 2 diabetes admitted via the emergency department.

  17. Radiation survey on Fukushima Medical University premises about four years after the Fukushima nuclear disaster

    Science.gov (United States)

    Omori, Yasutaka; Wakamatsu, Hiroaki; Sorimachi, Atsuyuki; Ishikawa, Tetsuo

    2016-01-01

    Abstract This study was conducted on the Fukushima Medical University (FMU) premises (in Fukushima City, Fukushima Prefecture) about four years after the Fukushima Daiichi Nuclear Power Plant accident. Its objectives were (1) to create a map of the ambient gamma dose rate (air-kerma rate) distribution, (2) to evaluate the air-kerma rate originating from natural radionuclides, and (3) to investigate the effects of snow cover on changes in the air-kerma rate. This man-borne survey revealed that the air-kerma rate varies widely, ranging from 0.038 μGy h-1 to 0.520 μGy h-1, and is higher on grass than on the other investigated surface types, such as soil, asphalt, and bricks. In this area, the mean air-kerma rate from natural radiation was evaluated to be 0.03 ± 0.01 μGy h-1, which is close to 0.04 μGy h-1, which was measured in central Fukushima City by a local authority.Furthermore, snowfall was found to reduce the air-kerma rate by 5%-30%. This reduction was attributed to attenuation of the primary radiation while passing through the snow cover, and the measured contribution of scattered radiation to the air-kerma rate reduction was small. The reduction rate was found to depend on the initial snow depth but to maintain a similar value for a couple of days, after the snow had partially melted and its depth had decreased. Finally, analysis of the daily dose due to external exposure received on the FMU premises revealed that no further health effects due to chronic radiation exposure at this site are to be expected. PMID:26911302

  18. Traumatic dental injuries in a university hospital: a four-year retrospective study.

    Science.gov (United States)

    Mahmoodi, Benjamin; Rahimi-Nedjat, Roman; Weusmann, Jens; Azaripour, Adriano; Walter, Christian; Willershausen, Brita

    2015-11-04

    Traumatic dental injuries present complex injuries of the dentoalveolar system. Aim of this study was to investigate the frequency and patterns of traumatic dental injuries in a University dental emergency service over four years. A retrospective investigation on all dental trauma patients presenting at the dental emergency service of the University Medical Center Mainz, Germany between 01/2010 and 12/2013 was conducted. Demographic data, the cause and type of trauma and the initial therapy were analyzed. Out of 16,301 patients, 1,305 patients (8 %; average age 14.7 years ±15.7; 60.1 % male, 39.9 % female) came due to trauma. 63.9 % of the traumas occurred on weekends. The most frequent reason for injuries was falls (54.6 %). No correlation could be found between the cause and the kind of trauma. In 48.6 % of the cases only one tooth was involved, in 33.5 % two. The permanent dentition was traumatized in 56.6 % of cases, the deciduous teeth in 41.1 %. The most frequently affected tooth was the central upper incisor (61.0 %). Hard-tissue injuries were significantly more frequent in the permanent dentition, while periodontal injuries were seen significantly more often in the deciduous dentition. Eight percent of all patients seeking help at the dental emergency service presented with trauma, meaning that dental traumatology is one of the major topics in emergencies. To improve the quality of care, further public education, expert knowledge among dental professionals and a well-structured emergency service are necessary.

  19. Radiation survey on Fukushima Medical University premises about four years after the Fukushima nuclear disaster.

    Science.gov (United States)

    Omori, Yasutaka; Wakamatsu, Hiroaki; Sorimachi, Atsuyuki; Ishikawa, Tetsuo

    2016-06-08

    This study was conducted on the Fukushima Medical University (FMU) premises (in Fukushima City, Fukushima Prefecture) about four years after the Fukushima Daiichi Nuclear Power Plant accident. Its objectives were (1) to create a map of the ambient gamma dose rate (air-kerma rate) distribution, (2) to evaluate the air-kerma rate originating from natural radionuclides, and (3) to investigate the effects of snow cover on changes in the air-kerma rate. This man-borne survey revealed that the air-kerma rate varies widely, ranging from 0.038 μGy h(-1) to 0.520 μGy h(-1), and is higher on grass than on the other investigated surface types, such as soil, asphalt, and bricks. In this area, the mean air-kerma rate from natural radiation was evaluated to be 0.03 ± 0.01 μGy h(-1), which is close to 0.04 μGy h(-1), which was measured in central Fukushima City by a local authority.Furthermore, snowfall was found to reduce the air-kerma rate by 5%-30%. This reduction was attributed to attenuation of the primary radiation while passing through the snow cover, and the measured contribution of scattered radiation to the air-kerma rate reduction was small. The reduction rate was found to depend on the initial snow depth but to maintain a similar value for a couple of days, after the snow had partially melted and its depth had decreased. Finally, analysis of the daily dose due to external exposure received on the FMU premises revealed that no further health effects due to chronic radiation exposure at this site are to be expected.

  20. Stomatal response of Pinus sylvestriformis to elevated CO2 concentrations during the four years of exposure

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yu-mei; HAN Shi-jie; LIU Ying; JIA Xia

    2005-01-01

    Four-year-old Pinus sylvestriformis were exposed for four growing seasons in open top chambers to ambient CO2 concentration (approx. 350 μmol·mol-1) and high CO2 concentrations (500 and 700 μmol·mol-1) at Research Station of Changbai Mountain Forest Ecosystems, Chinese Academy of Sciences at Antu Town, Jilin Province, China (42oN, 128oE). Stomatal response to elevated CO2 concentrations was examined by stomatal conductance (gs), ratio of intercellular to ambient CO2 concentration (ci/ca) and stomatal number. Reciprocal transfer experiments of stomatal conductance showed that stomatal conductance in high-[CO2]-grown plants increased in comparison with ambient-[CO2]-grown plants when measured at their respective growth CO2 concentration and at the same measurement CO2 concentration (except a reduction in 700 μmol·mol-1 CO2 grown plants compared with plants on unchambered field when measured at growth CO2 concentration and 350 μmol·mol-1CO2). High-[CO2]-grown plants exhibited lower ci/ca ratios than ambient-[CO2]-grown plants when measured at their respective growth CO2 concentration. However, ci/ca ratios increased for plants grown in high CO2 concentrations compared with control plants when measured at the same CO2 concentration. There was no significant difference in stomatal number per unit long needle between elevated and ambient CO2. However, elevated CO2 concentrations reduced the total stomatal number of whole needle by the decline of stomatal line and changed the allocation pattern of stomata between upper and lower surface of needle.

  1. Four-year record of mercury wet deposition in one typical industrial city in southwest China

    Science.gov (United States)

    Qin, Caiqing; Wang, Yongmin; Peng, Yulong; Wang, Dingyong

    2016-10-01

    During the period from December 2010 to November 2014, long-term monitoring of Hg wet deposition was conducted at three sites in Chongqing. The four-year volume-weighted mean concentrations (VWC) of total mercury (THg) and methylmercury (MeHg) in precipitation were 34.25 ng L-1 and 0.48 ng L-1, respectively. The average annual wet deposition fluxes were 37.83 ± 11.53 μg m-2 yr-1 for THg and 0.61 ± 0.19 μg m-2 yr-1 for MeHg. Besides, the average proportion of MeHg in THg was 1.41%. These data were well ahead of values observed in most of other areas. The annual VWC of Hg rose remarkably in 2012 and then reached a plateau or climbed mildly in the following 2 years, while its annual wet deposition fluxes saw an upward trend throughout the whole period. In addition, the high figures of Hg concentration were generally found in the non-monsoon seasons, but its elevated wet deposition fluxes normally appeared in the rainy seasons. These characteristics of inter-annual and seasonal changes for VWC and fluxes were observed at every sampling site in this study as well. Besides, there were significantly spatial distributions for VWC and fluxes of THg in the descending order of the downtown (NA), the suburban (BB) and the controlled site (JY). While for MeHg, BB had the largest values, followed by NA and JY. So apart from THg load, the formation of MeHg was influenced by other factors in Chongqing, like the concentration of reactive mercury (RHg) in precipitation. Additionally, particulate bound mercury (PHg) is the dominant form among various Hg species, and atmospheric Hg is effectively eliminated during the initial period of the rain event and the below-cloud scavenging is the predominant mechanism contributing Hg to precipitation.

  2. Malaria Four-year Epidemiological Trends in Sistan and Baluchistan Province, Iran

    Science.gov (United States)

    Norouzinezhad, Faezeh; Ghaffari, Fatemeh; Raeisi, Ahmad; Norouzinejad, Abbas; Kaveh, Farzad

    2017-01-01

    Introduction Malaria is one of the foremost public health concerns in Iran, where more than 90% of malaria cases are reported in the southern and south-eastern areas of the country. The aim of this study was to assess the epidemiological trends of malaria over a four-year period in in the Sistan and Baluchistan province in south east of Iran. Methods This descriptive epidemiological study examined malaria trends in Sistan and Baluchistan province from 2011 to 2014. The study used data collected in accordance with the Iranian Ministry of Health’s malaria control and elimination protocol. This protocol has digitized the data reporting system for malaria, and all information were sent online to the Center of Disease Control in the Ministry of Health. In this manner, information on malaria cases in Sistan and Baluchistan were made available for the researchers to analyze. Descriptive and comparative analyses were conducted using the SPSS version 13. Results Annual incidence rates reported in 2011, 2012, 2013, and 2014 showed the prevalence of 89.9, 43.9, 38.3 and 36.6 (per 100,000 persons), respectively. Across all 4 years, the highest numbers of cases were found in persons 16–25 years old and among males. Most of the infected individuals were villagers and workers. In total, 64.8% of patients were Iranian and 29.5% were Pakistani. The highest number of cases was diagnosed in the cities of Sarbaz and Chabahar, with 1,742 and 1,707 cases, respectively. The results showed that over the last 4 years, 50.8% of cases have entered into Iran from foreign countries. The majority of cases involved parasites in the trophozoite stage of the life cycle. In terms of surveillance, passive care was reported in the majority of cases, and vivax malaria had the highest prevalence in comparison with other types. Conclusion The findings are showing that the care, control and treatment system applied to Sistan and Baluchistan province has had a positive effect on decreasing the

  3. Hypothyroidism - A cause for dilated cardiomyopathy in dogs; four year study (2008-2011

    Directory of Open Access Journals (Sweden)

    Satish Kumar Karlapudi

    Full Text Available Aim: The study was carried out to understand the thyroid dysfunction and its association with dilated cardiomyopathy in dogs. Materials and Methods: The study was done at Teaching Veterinary Hospital, Bhoiguda, College of Veterinary Science, Hyderabad for four years, i.e., from 2008 to 2011. A total of 256 dogs of various breed, age and sex were presented with typical skin and coat abnormalities. Few were also exhibiting signs of low metabolic rate. Skin sample analysis was done to rule out the causes of dermatitis. Thyroid profile was estimated to diagnose hypothyroidism. Selected cases were also subjected for echocardiography to study the association of cardiomyopathy. Based on thyroid profile, hypothyroid dogs were treated with levothyroxine @20mcg/kg wt, once daily, orally on empty stomach and dilated cardiomyopathy (DCM associated patients were additionally supplemented with enalapril @0.5 mg/kg, twice daily, orally for 6 months. The hemato biochemical and echocardiographic aspects are discussed. Results: The classical signs that were recorded in almost all the thyroid dysfunction dogs (231 were bilateral alopecia, rat tail and pigmentation and whereas, dyspnoea at rest, exercise intolerance, obesity, pale mucosae and corneal lipidosis were the significant low metabolic rate signs noticed in 42 dogs. However, syncope and seizures were also recorded in 31 of these hypothyroid dogs. Echocardiographic evaluation revealed significantly (P<0.01 increased LVEDd and LVEDs along with decreased IVS and LVPW both at systole and diastole among 33 dogs. Normocytic, normochromic and non-regenerative anemia and significantly (P<0.05 low T3, fT4, tT4 along with elevated serum cholesterol, triglycerides, TSH, CKMB, LDH and ALP were the hemato – biochemical findings among these dogs. After the initiation of therapy, improvement in clinical signs was noticed from day 7 and complete clinical recovery by the end of therapy. However, a non significant

  4. A Four-Year Longitudinal Study on Restless Legs Syndrome in Parkinson Disease

    Science.gov (United States)

    Moccia, Marcello; Erro, Roberto; Picillo, Marina; Santangelo, Gabriella; Spina, Emanuele; Allocca, Roberto; Longo, Katia; Amboni, Marianna; Palladino, Raffaele; Assante, Roberta; Pappatà, Sabina; Pellecchia, Maria Teresa; Barone, Paolo; Vitale, Carmine

    2016-01-01

    dopaminergic pathways, and worse sleep and cardiovascular disturbances. Citation: Moccia M, Erro R, Picillo M, Santangelo G, Spina E, Allocca R, Longo K, Amboni M, Palladino R, Assante R, Pappatà S, Pellecchia MT, Barone P, Vitale C. A four-year longitudinal study on restless legs syndrome in Parkinson disease. SLEEP 2016;39(2):405–412. PMID:26564123

  5. Four-year outcome of a PI and NRTI-sparing salvage regimen: maraviroc, raltegravir, etravirine.

    Science.gov (United States)

    Nozza, Silvia; Galli, Laura; Bigoloni, Alba; Gianotti, Nicola; Spagnuolo, Vincenzo; Carbone, Alessia; Chiappetta, Stefania; Ripa, Marco; Tambussi, Giuseppe; Lazzarin, Adriano; Castagna, Antonella

    2014-04-01

    Aim of this study was to report the 204-week efficacy and safety results of a novel PI- and NRTI-sparing regimen for salvage therapy including maraviroc, raltegravir, etravirine in 28 failing HIV-infected patients with R5-tropic virus. The trend of laboratory parameters was tested by ANOVA for repeated measures and Greenhouse-Geisser probabilities were reported. Results were described as median (Q1-Q3) values. Twenty-six (93%) out of 28 patients completed 204 weeks of treatment. Virological success (HIV-RNA<50 copies/mL) at week 204 was 96%. CD4+ counts significantly increased [244 (158-213) cells/mm3, p<0.0001] from baseline [247 (68-355) cells/mm(3)] as well as CD4+ percentage. Four serious adverse events (1 death due to Hodgkins's lymphoma, 1 anal cancer, 1 Hodgkins's lymphoma, 1 recurrence of mycobacterial spondylodiscitis) were observed; three events led to transitory discontinuation of the antiretroviral therapy due to drug-drug interaction. BMI (p<0.0001) and waist circumference (p<0.0001) significantly increased over 204 weeks. An amelioration was also observed in relation to haemoglobin (p=0.0006), platelets (p<0.0001), white blood cell (p=0.013), neutrophils (p=0.301), lymphocytes (p=0.207) and creatinine (p<0.0001). In highly treatment-experienced patients the maraviroc, raltegravir and etravirine combination is associated with a good long-term efficacy and safety profile.

  6. A Measurement of Electron Neutrino Appearance in the MINOS Experiment After Four Years of Data

    Energy Technology Data Exchange (ETDEWEB)

    Cavanaugh, Steven [Harvard Univ., Cambridge, MA (United States)

    2010-05-01

    experiment. After two years of running with 3.14 x 1020 protons-on-target (POT), a limit was set at δCP = 0 for the normal (inverted) hierarchy of sin2(2θ13) < 0.29 (0.42) at 90% C.L. This study finds after four years of data with an accumulated intensity of 7 x 1020 POT that sin2(2θ13) < 0.12 (0.20) with δCP = 0 at 90% C.L. for the normal (inverted) hierarchy.

  7. Four-year clinical outcome in asymptomatic patients undergoing coronary computed tomography angiography

    Institute of Scientific and Technical Information of China (English)

    ZHANG Kai-yi; GAI Lu-yue; GAI Jing-jing; HE Bin; GUAN Zhi-wei

    2013-01-01

    Background Percutaneous coronary intervention (PCI) is indicated for angina with coronary stenosis.However,PCI for asymptomatic coronary stenosis remains controversial.We prospectively followed a group of patients for four years who underwent coronary computed tomography angiography (CCTA) for major adverse cardiac events (MACE).We hypothesized that the results of this trial would reliably reflect the natural outcome of the coronary disease.Methods Consecutive patients who underwent CCTA from June 2008 to May 2009 were selected.Those who could not be reached by telephone,had significant angina,had CT images that were not interpretable,or poor kidney and left ventricular (LV) function were excluded.The patients were divided into five groups:group A normal CCTA without stenosis,group B mild stenosis (1%-49%),group C moderate stenosis (50%-74%),group D severe stenosis (≥75%) and they were treated with optimal medical therapy (OMT) or PCI.The group E had PCI before the CCTA examination.The patients were then followed for MACE after different treatments.MACE included acute myocardial infarction (MI),heart failure (HF) and death.Results The patient population consisted of 419 patients.The follow-up time was (51±5) months.The age was (60±31)years.Male made up 67.78% of the population (n=284).A total of 51 cases of MACE occurred including 25 MI,eight HF and 18 all-cause deaths.There was no MACE in group A.Although MACE occurred in two patients in group B,they were not attributed to cardiac death.We further compared the MACE in groups C-E and no significant difference was found (P >0.05).However,a difference was detected among patients with unstable angina pectoris (UAP),stable angina pectoris (SAP),re-hospitalization,and cerebrovascular events from groups A-E (P <0.05).The plaque scores were used to predict MACE.The scores progressively increased significantly with lesion severity (P <0.05).Receiver operating curve (ROC) was performed to determine the

  8. Four-year follow-up study of pharmacological treatment in pathological gamblers.

    Science.gov (United States)

    Rosenberg, Oded; Dinur, Limor Klein; Dannon, Pinhas N

    2013-01-01

    In the past decade, we have witnessed the emergence of pharmacological treatments for pathological gambling with some success but many question marks. We aimed to explore pharmacological treatments that have been previously explored with some success, with the intent of comparing their efficacy and pave the way to larger placebo-controlled trials. In this study, we allocated 78 patients to 4 different types of psychotropic medications: naltrexone, topiramate, bupropion, and escitalopram. We treated patients for more than 2 years, with additional 2-year follow-ups without medication. The sample was evaluated using the 21-item Hamilton Depression Rating Scale, the Hamilton Anxiety Rating Scale, the Global Assessment of Functioning, and the Visual Analog Scale to measure general well-being before enrollment as well as at 1 month, 6 months, 24 months, and 48 months after beginning medication treatment. During the first 2 years of treatment, 34 patients dropped out, with one more dropping out during the additional 2 years of follow-up. Significant improvement on all rating scales was seen in all groups after 2 years, except HAMD in the group that received topiramate. We found the naltrexone-treated group of patients to have a statistically significant lower dropout rate compared with other groups, statistically significant lower HAMD scores in comparison to the group treated with bupropion, statistically significant lower Hamilton Anxiety Rating Scale score compared to the groups treated with escitalopram and topiramate, and significantly higher Visual Analog Scale scores compared to the groups treated with bupropion and topiramate. Pathological gambling is essentially a biopsychological disorder that may be attenuated provided that patients adhere to medication. In our study, among 4 medications with different mechanisms of action, naltrexone was found to be the most effective. Placebo-controlled studies involving large numbers of subjects are required before

  9. Subjective memory complaints in primary care patients and death from all causes: a four-year follow-up

    DEFF Research Database (Denmark)

    Siersma, Volkert Dirk; Waldemar, Gunhild; Waldorff, Frans Boch

    2013-01-01

    -related quality of life were collected at the enrolment primary care consultation. Dates of death from all causes occurring during the four-year follow-up were retrieved from the national databases. Cox proportional hazard regression models on time to death (censored after four years) were used to examine......OBJECTIVE: To investigate the prognostic value of subjective memory complaints for all-cause mortality in order to determine whether elderly persons with subjective memory complaints may be regarded as a group of vulnerable patients who need close follow-up. DESIGN: Prospective cohort study...... the influence of subjective memory complaints on all-cause mortality. RESULTS: 88 patients died during the four-year follow-up. The association between subjective memory complaints and mortality had a statistically not significant hazard ratio (HR) of 0.91, adjusting for known confounders. Statistically...

  10. Weakness and numbness of extremities with bowel and bladder dysfunction for four years

    Directory of Open Access Journals (Sweden)

    Han-hui FU

    2017-03-01

    Full Text Available The patient was a 53-year-old female who was admitted for “numbness and weakness of lower extremities, urinary and defecation dysfunction for 4 years” in September 2016.  Four years ago, the patient felt numbness and weakness of lower extremities, with chest zonesthesia and back pain. The weakness of left lower extremity got severer next morning and she cannot feel her left foot on the pedal when riding bicycle. At night, she presented numbness under umbilicus level, feet scuff and urine retention. She was also unable to squat. No fever, headache, vomiting or visual defect was found. She was treated as stroke which showed no effect. Two days later, the numbness extended to thoracic level with no sweating below, dyspnea, deep voice, bucking, dysphagia and weakness of both upper and lower extremities. Spinal MRI showed a long T1 signal and long T2 signal extended cervical cord lesion from C4-T5 segments and spinal cord swelling. She was suspected to have multiple sclerosis (MS or neuromyelitis optica (NMO, thus prednisone was given that resulted in the improvement other than numbness of lower extremities, stagger and bladder dysfunction. In the following 4 years, alike symptoms relapsed every year. Though the glucocorticoid treatment was helpful for symptoms remission, sequelae including extremities numbness, weakness, stagger, urinary incontinence and intermittent constipation were left. The predisposing and relieving factors were unclear for relapse. Six months ago, the patient stopped the glucocorticoid treatment by herself, followed by the increase of attack frequencies. One month ago, she got diplopia in the right eye. The patient was admitted for further diagnosis and treatment. Since the onset of symptoms, the patient has been conscious. The appetite and defecation have been normal. No dryness of mouth and eye, shin rash, Reynolds Syndrome, photosensitization and joint pain was noticed. She has a weight loss of 5kg, during which time

  11. Four-year follow up of hepatitis C patients vaccinated against hepatitis B virus

    Institute of Scientific and Technical Information of China (English)

    Slawomir Chlabicz; Tadeusz Wojciech Lapinski; Anna Grzeszczuk; Danuta Prokopowicz

    2005-01-01

    AIM: Patients with chronic hepatitis C have been recommended to receive vaccinations against hepatitis B. Our study aimed at evaluating the hepatitis B immunogenicity and efficacy against hepatitis B virus infection 4 years after primary immunization series in a group of patients with chronic hepatitis C.METHODS: We recruited 36 out of 48 hepatitis C virus (HCV) infected individuals who were vaccinated against hepatitis B virus (20 μg of recombinant HBsAg at 0-1-6mo schedule) in 1998. Here we measured anti-HBs titers and anti-HBc 4 years after delivery of the third dose of primary immunization series.RESULTS: After 4 years a total of 13/36 (36%) HCV infected patients had seroprotective titers of anti-HBs compared with 9/10 (90%) in the control group, (P<0.05).Similarly the mean concentration of anti-HBs found in hepatitis C patients was significantly lower than that found in healthy subjects (18.3 and 156.0 mIU/mL respectively (P<0.05). None of the HCV infected patients or controls became infected with HBV during the study period as confirmed by anti-HBc negativity.CONCLUSION: We demonstrated that 4 years after HBV immunizations' more than 60% of vaccinated HCV patients did not maintain seroprotective levels of anti-HBs, which might put them at risk of clinically significant breakthrough infections. Further follow-up studies are required to clarify whether memory B and T lymphocytes can provideprotection in chronic hepatitis C patients in the absence or inadequate titers of anti-HBs.

  12. In-School Work Experience and the Returns to Two-Year and Four-Year Colleges

    Science.gov (United States)

    Molitor, C.J.; Leigh, D.E.

    2005-01-01

    Building on the existing education literature, we address two interrelated questions. First, how sensitive are estimated returns to two-year and four-year colleges to the inclusion of in-school work experience? Second, do the estimated returns to in-school work experience vary by type of educational institution attended? Regarding the first…

  13. Experiences of Female Faculty with Maternity Leave at Four-Year Universities in an Upper Midwest State

    Science.gov (United States)

    Myerchin, Audra Dawn

    2012-01-01

    The purpose of this mixed methods study was to explore female faculty members' experiences with maternity leave, while working as a career academic in higher education. Participants consisted of women currently employed in an upper Midwest state at six four-year institutions. An online survey was completed by 121 women, and 30 of these women also…

  14. Preventing errors in administration of parenteral drugs: the results of a four-year national patient safety program.

    NARCIS (Netherlands)

    Blok, C. de; Schilp, J.; Wagner, C.

    2013-01-01

    Objectives: To evaluate the implementation of a four-year national patient safety program concerning the parenteral drug administration process in the Netherlands. Methods: Structuring the preparation and administration process of parenteral drugs reduces the number of medication errors. A nationwid

  15. Prediction of Job Satisfaction Based on Workplace Facets for Adjunct Business Faculty at Four-Year Universities

    Science.gov (United States)

    Lewis, Vance Johnson

    2012-01-01

    The purpose of this study was to examine the job satisfaction of adjuncts in the curriculum area of business at four-year universities and to determine the roles that individual job facets play in creating overall job satisfaction. To explore which job facets and demographics predict job satisfaction for the population, participants were asked to…

  16. The Effects of Deep Approaches to Learning on Students' Need for Cognition over Four Years of College

    Science.gov (United States)

    Wang, Jui-Sheng

    2013-01-01

    This study examines the effect of deep approaches to learning on development of the inclination to inquire and lifelong learning over four years, as an essential graduated outcome that helps students face the challenges of a complex and rapidly changing world. Despite the importance of the inclination to inquire and lifelong learning, some…

  17. Using Time-on-Task Measurements to Understand Student Performance in a Physics Class: A Four-Year Study

    Science.gov (United States)

    Stewart, John; Stewart, Gay; Taylor, Jennifer

    2012-01-01

    Student use of out-of-class time was measured for four years in the introductory second-semester calculus-based physics course at the University of Arkansas. Two versions of the course were presented during the time of the measurement. In both versions, the total out-of-class time a student invested in the course explained less than 1% of the…

  18. Practices of Early Childhood Development Practitioners for Poor and Vulnerable Children from Birth to Four Years in South Africa

    Science.gov (United States)

    Ebrahim, Hasina Banu; Killian, Bev; Rule, Peter

    2011-01-01

    This article explores the practices undertaken by early childhood development practitioners (ECDPs) to support poor and vulnerable children from birth to four years outside centre-based provision. The article draws on part of a UNICEF (United Nations International Children's Fund) commissioned evaluation on family and community-based ECD (Early…

  19. Top Gainers: Some Public Four-Year Colleges and Universities Make Big Improvements in Minority Graduation Rates. College Results Online

    Science.gov (United States)

    Engle, Jennifer; Theokas, Christina

    2010-01-01

    Each year, nearly 400,000 minority students enroll as freshmen in a four-year college, hoping to realize all of the opportunities that earning a bachelor's degree affords. Many arrive on campus having overcome underfunded high schools, an intimidating college-admissions process, and daunting financial circumstances. Yet despite their persistence…

  20. The national neonatal screening programme for congenital toxoplasmosis in Denmark: results from the initial four years, 1999-2002

    DEFF Research Database (Denmark)

    Schmidt, Dorte Remmer; Høgh, Birthe; Andersen, O

    2006-01-01

    AIMS: To describe the outcome of four years' nationwide neonatal screening for congenital toxoplasmosis in liveborn newborns. METHODS: Congenital toxoplasmosis was diagnosed if specific Toxoplasma gondii IgM antibodies were detected in eluate from the PKU Guthrie filter paper card from a child...

  1. Three-to Four-Year-Olds' Recognition That Symbols Have a Stable Meaning: Pictures Are Understood Before Written Words

    Science.gov (United States)

    Apperly, Ian. A.; Williams, Emily; Williams, Joelle

    2004-01-01

    In 4 experiments 120 three-to four-year-old non readers were asked the identity of a symbolic representation as it appeared with different objects. Consistent with Bialystok (2000), many children judged the identity of written words to vary according to the object with which they appeared but few made such errors with recognizable pictures.…

  2. Using Time-on-Task Measurements to Understand Student Performance in a Physics Class: A Four-Year Study

    Science.gov (United States)

    Stewart, John; Stewart, Gay; Taylor, Jennifer

    2012-01-01

    Student use of out-of-class time was measured for four years in the introductory second-semester calculus-based physics course at the University of Arkansas. Two versions of the course were presented during the time of the measurement. In both versions, the total out-of-class time a student invested in the course explained less than 1% of the…

  3. An Academic Comparison of Third Grade Reading Scores: Reflecting the Impact of Four-Year-Old Kindergarten

    Science.gov (United States)

    Towns, Debra

    2013-01-01

    In Wisconsin, increased academic performance has been a general assumption supporting the institutionalization and public funding of early childhood instruction. The purpose of this study was to determine if there was a relationship between attendance in public four-year-old kindergarten and elementary level reading performance. This study…

  4. Preventing errors in administration of parenteral drugs: the results of a four-year national patient safety program.

    NARCIS (Netherlands)

    Blok, C. de; Schilp, J.; Wagner, C.

    2013-01-01

    Objectives: To evaluate the implementation of a four-year national patient safety program concerning the parenteral drug administration process in the Netherlands. Methods: Structuring the preparation and administration process of parenteral drugs reduces the number of medication errors. A nationwid

  5. Practices of Early Childhood Development Practitioners for Poor and Vulnerable Children from Birth to Four Years in South Africa

    Science.gov (United States)

    Ebrahim, Hasina Banu; Killian, Bev; Rule, Peter

    2011-01-01

    This article explores the practices undertaken by early childhood development practitioners (ECDPs) to support poor and vulnerable children from birth to four years outside centre-based provision. The article draws on part of a UNICEF (United Nations International Children's Fund) commissioned evaluation on family and community-based ECD (Early…

  6. An Examination of Early Retirement Plans for Faculty at Four-Year Private Colleges in New England.

    Science.gov (United States)

    Kennedy, M. Patricia

    College faculty early retirement plans at four-year private colleges in New England are compared to determine requirements for an early retirement policy. Findings from survey responses from 82 colleges included: 20 of the colleges had an early retirement plan; 90% of schools with an early retirement plan had a tenure policy; 25% of the schools…

  7. A comparison of four years of limnology in the Sawtooth Lakes with emphasis on fertilization in Redfish Lake

    Energy Technology Data Exchange (ETDEWEB)

    Budy, P.; Luecke, C.; Wurtsbaugh, W.A.

    1996-05-01

    Included in this section of the report on limnology of Lakes in the Snake River Plain are descriptions of four years of limnological sampling to compare inter and intra annual variability in lake productivity to evaluate potential rearing conditions for juvenile sockeyed salmon. Data was used to evaluate the effects of nutrient enhancement, annual weather patterns, and planktivore consumption on lake productivity.

  8. Health care costs in the last four years of life for private health plan beneficiaries in Brazil.

    Science.gov (United States)

    Ferraz, Marcos Bosi; Miranda, Isaura Cristina; Padovan, Jorge; de Soárez, Patricia Coelho; Ciconellil, Rozana

    2008-08-01

    To examine health care use and expenditures by Brazilians covered by private health care plans in the last four years of life. Health plan provider enrollee files and death certificate data were used for 274 health plan beneficiaries who died in 1998, 1999, and 2000. Resources used for a beneficiary in the year of death and in the three years prior to death were identified. Descriptive statistical analyses were used for clinical and socio-demographic characteristics and to describe the costs. Of the 274 deaths included in this analysis, 92 occurred in 1998, 82 in 1999, and 100 in 2000. Most of the deceased were males (61.4%). Distribution in terms of type of health plan coverage (full versus hospitalization-only coverage) was similar among beneficiaries (53% had hospitalization only and 47% had full coverage). The total health plan expenditure in the last four years of life for the 274 decedents was US$ 26,300,283 (US$ 12,287,723 for beneficiaries with hospitalization-only and US$ 14,012,560 for those with full coverage). Expenditures increased progressively in the four years preceding death. About 70% of medical expenses for decedents in the four years of this analysis were incurred in the last year of life. Relatively large amounts of health care resources are used by Brazilian private health plan participants in their last year of life, suggesting that specific strategies are needed to optimize the allocation of medical care resources for these patients.

  9. Developments in Instruction in Selected Four Year College Reading Improvement Programs Throughout the United States, 1950-1974.

    Science.gov (United States)

    Howard, Virginia Pearl Hymes

    The purpose of this study was to examine the organization, program format and duration of college reading improvement instructional programs (CRIPs) in selected four-year American colleges and universities from 1950-1974, and to gather information which is vital to effective curricula and planning for higher education in the area of reading…

  10. What's Happened to the Price of College? Quality-Adjusted Net Price Indexes for Four Year Colleges

    Science.gov (United States)

    Schwartz, Amy Ellen; Scafidi, Benjamin

    2004-01-01

    Hedonic models of the price of college to construct quality-adjusted net price indexes for U.S. four-year colleges were estimated. A 22 percent decline in the estimated price index is reported by adjusting for financial aid, while quality adjusting results lead to a smaller decline, for academic years 1990-91 to 1994-95.

  11. Local Control, Toxicity, and Cosmesis in Women >70 Years Enrolled in the American Society of Breast Surgeons Accelerated Partial Breast Irradiation Registry Trial

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Atif J., E-mail: atif_khan@rwjuh.edu [Robert Wood Johnson University Hospital, Cancer Institute of New Jersey, New Brunswick, NJ (United States); Vicini, Frank A.; Beitsch, Peter [American Society of Breast Surgeons, Columbia, MD (United States); Goyal, Sharad [Robert Wood Johnson University Hospital, Cancer Institute of New Jersey, New Brunswick, NJ (United States); Kuerer, Henry M.; Keisch, Martin; Quiet, Coral; Zannis, Victor; Keleher, Angela; Snyder, Howard; Gittleman, Mark; Whitworth, Pat; Fine, Richard [American Society of Breast Surgeons, Columbia, MD (United States); Lyden, Maureen [BioStat International, Inc., Tampa, FL (United States); Haffty, Bruce G. [Robert Wood Johnson University Hospital, Cancer Institute of New Jersey, New Brunswick, NJ (United States); American Society of Breast Surgeons, Columbia, MD (United States)

    2012-10-01

    Purpose: The American Society of Breast Surgeons enrolled women in a registry trial to prospectively study patients treated with the MammoSite Radiation Therapy System breast brachytherapy device. The present report examined the outcomes in women aged >70 years enrolled in the trial. Methods and Materials: A total of 1,449 primary early stage breast cancers were treated in 1,440 women. Of these, 537 occurred in women >70 years old. Fisher's exact test was performed to correlate age ({<=}70 vs. >70 years) with toxicity and with cosmesis. The association of age with local recurrence (LR) failure times was investigated by fitting a parametric model. Results: Older women were less likely to develop telangiectasias than younger women (7.9% vs. 12.4%, p = 0.0083). The incidence of other toxicities was similar. Cosmesis was good or excellent in 92% of the women >70 years old. No significant difference was found in LR as a function of age. The 5-year actuarial LR rate with invasive disease for the older vs. younger population was 2.79% and 2.92%, respectively (p = 0.5780). In women >70 years with hormone-sensitive tumors {<=}2 cm who received hormonal therapy (n = 195), the 5-year actuarial rate of LR, overall survival, disease-free survival, and cause-specific survival was 2.06%, 89.3%, 87%, and 97.5%, respectively. These outcomes were similar in women who did not receive hormonal therapy. Women with small, estrogen receptor-negative disease had worse LR, overall survival, and disease-free survival compared with receptor-positive patients. Conclusions: Accelerated partial breast irradiation with the MammoSite radiation therapy system resulted in low toxicity and produced similar cosmesis and local control at 5 years in women >70 years compared with younger women. This treatment should be considered as an alternative to omitting adjuvant radiotherapy for older women with small-volume, early-stage breast cancer.

  12. Show or tell: testimony is sufficient to induce the curse of knowledge in three- and four-year-olds.

    Science.gov (United States)

    Bhandari, Keera; Barth, Hilary

    2010-02-01

    Because much of what children learn extends beyond their first-hand experience, they are reliant upon the testimony of others to acquire information about aspects of the world they have not experienced directly. Here we asked whether testimony alone would be sufficient to induce cognitive biases in knowledge attribution that have been observed when children acquire information through direct observation. A total of 80 three- and four-year-old children were tested on a "curse of knowledge" task to assess their inability to override their own knowledge when asked to assess the knowledge of a nave other. In the present study, we tested children's ability to override knowledge gained through testimony rather than knowledge gained through visual experience. Testimony alone was sufficient to induce the curse of knowledge in three- and four-year-olds. Knowledge obtained through the testimony of others is apparently subject to some of the same cognitive biases that are present when children learn through observation.

  13. Comparison of performance in a four year graduate entry medical programme and a traditional five/six year programme.

    OpenAIRE

    Byrne, Annette T.; Arnett, Richard; Farrell, Tom; Sreenan, Seamus

    2014-01-01

    Background In 2006 the Royal College of Surgeons in Ireland, (RCSI), introduced the first four year Graduate Entry Programme (GEP) in medicine in Ireland in line with national policy to broaden access to medical education. One concern considered at the time, was whether the GEP students could be trained to the same standard as their undergraduate Direct Entry Programme (DEP, five/six year duration) counterparts in the shorter time frame. Since students from both cohorts undertake the same exa...

  14. Modifiable risk factors predicting major depressive disorder at four year follow-up: a decision tree approach

    Directory of Open Access Journals (Sweden)

    Christensen Helen

    2009-11-01

    Full Text Available Abstract Background Relative to physical health conditions such as cardiovascular disease, little is known about risk factors that predict the prevalence of depression. The present study investigates the expected effects of a reduction of these risks over time, using the decision tree method favoured in assessing cardiovascular disease risk. Methods The PATH through Life cohort was used for the study, comprising 2,105 20-24 year olds, 2,323 40-44 year olds and 2,177 60-64 year olds sampled from the community in the Canberra region, Australia. A decision tree methodology was used to predict the presence of major depressive disorder after four years of follow-up. The decision tree was compared with a logistic regression analysis using ROC curves. Results The decision tree was found to distinguish and delineate a wide range of risk profiles. Previous depressive symptoms were most highly predictive of depression after four years, however, modifiable risk factors such as substance use and employment status played significant roles in assessing the risk of depression. The decision tree was found to have better sensitivity and specificity than a logistic regression using identical predictors. Conclusion The decision tree method was useful in assessing the risk of major depressive disorder over four years. Application of the model to the development of a predictive tool for tailored interventions is discussed.

  15. Anastomosing hemangioma arising from the kidney: a case of slow progression in four years and review of literature

    Science.gov (United States)

    Zhang, Wei; Wang, Qiang; Liu, Yu-Lin; Yu, Wen-Juan; Liu, Yan; Zhao, Hui; Zhuang, Jie; Jiang, Yan-Xia; Li, Yu-Jun

    2015-01-01

    Reported herein is a renal anastomosing hemangioma which developed slowly in the past four years. A 25-year-old woman was found a mass localized in the upper portion four years ago, and only slow progression in the past four years. She underwent a laparoscopic partial nephrectomy of right kidney and diagnosed as anastomosing hemangioma. On histology the vascular components of the tumor had an anastomosing pattern without well-definite margins. Immunohistochemically, only endothelial markers (CD31, CD34) were expressed on the vascular components of tumor cells. Smooth muscle actin (SMA), cytokeratin (CK), EMA and S-100 and so on were all negative in the epithelioid tumor cells. The patient was alive at 16 months after operation, without any evidence recurrence or metastasis. Anastomosing hemangioma is an extremely rare vascular neoplasm; only 23 cases were previously described until now. Our report of anastomosing hemangioma arising from the kidney with slow progression will improve the knowledge of primary vascular tumors arising in the kidney. PMID:25973131

  16. Coping With Strain (CWS) course - its effects on depressive symptoms: A four-year longitudinal randomized controlled trial.

    Science.gov (United States)

    Saelid, Gry Anette; Czajkowski, Nikolai Olavi; Holte, Arne; Tambs, Kristian; Aarø, Leif Edvard

    2016-08-01

    The Coping With Strain (CWS) course is a modification of the Coping With Depression (CWD) course. CWD is by far the most studied psycho-educational intervention to reduce and prevent depression, but CWD has never been tested in a randomized controlled trial in the workplace. This study seeks to examine the extent to which CWS, on a short-term and a long-term basis, reduces depressive symptoms in employees. After advertising at workplaces, 119 employees were randomized into Intervention Group I (IG1), which immediately participated in CWS, or Intervention Group II (IG2), which functioned as a control group for six months until its participation in CWS. The follow up period lasted for four years in both IG1 and IG2. Linear mixed models were fitted to the data. Depressive symptoms were significantly reduced during the course. The reduction of depressive symptoms was maintained over a period of four years in both IG1 and IG2, although there is a slight increase towards the end of the follow-up period. CWS is effective in reducing depressive symptoms among employees. The effects are long lasting and may be maintained over a period of four years.

  17. Clinical outcomes, toxicity, and cosmesis in breast cancer patients with close skin spacing treated with accelerated partial breast irradiation (APBI) using multi-lumen/catheter applicators.

    Science.gov (United States)

    Akhtari, Mani; Abboud, Mirna; Szeja, Sean; Pino, Ramiro; Lewis, Gary D; Bass, Barbara L; Miltenburg, Darlene M; Butler, E Brian; Teh, Bin S

    2016-12-01

    Accelerated partial breast irradiation (APBI) using a single-lumen device is associated with better cosmetic outcomes if the spacing between the applicator and skin is > 7 mm. However, there are no reports addressing the late toxicity and clinical outcomes in patients treated with single-entry multi-lumen/catheter applicators who had close skin spacing (7 mm or less). We undertook this study to report clinical outcome, acute and late toxicity as well as cosmesis of early stage breast cancer patients with close skin spacing treated with APBI using multi-lumen or multi-catheter devices. This is a retrospective study of all breast cancer patients who had undergone APBI using single-entry multi-lumen/catheter devices in a single institution between 2008 to 2012. The study was limited to those with ≤ 7 mm spacing between the device and skin. We identified 37 patients and 38 lesions with skin spacing of ≤ 7 mm. Seven lesions (18%) had spacing of ≤ 3 mm. Median follow-up was 47.5 months. There was one case of ipsilateral breast recurrence and one ipsilateral axillary recurrence. Based on RTOG criteria, 22 treated lesions experienced grade 1 and 9 lesions experienced grade 2 toxicity. Twenty-one lesions experienced late grade 1 toxicity. One patient had to undergo mastectomy due to mastitis. Twenty-four treated breasts showed excellent and 11 had good cosmetic outcome. Overall cosmesis trended towards a significant correlation with skin spacing. However, all patients with ≤ 3 mm skin spacing experienced acute and late toxicities. Accelerated partial breast irradiation can be safely performed in patients with skin spacing of ≤ 7 mm using single-entry multi-lumen/catheter applicators with excellent cosmetic outcomes and an acceptable toxicity profile. However, skin spacing of ≤ 3 mm is associated with acute and late toxicity and should be avoided if possible.

  18. Accelerated partial breast irradiation using once-daily fractionation: analysis of 312 cases with four years median follow-up

    Directory of Open Access Journals (Sweden)

    Shaikh Arif Y

    2012-02-01

    Full Text Available Abstract Background There are limited data on accelerated partial breast irradiation (APBI using external beam techniques. Moreover, there are recent reports of increased fibrosis and unacceptable cosmesis with APBI using external beam with BID fractionation. We adopted a once daily regimen of APBI with fractionation similar to that shown to be effective in a Canadian randomized trial of whole breast irradiation. It is unclear whether patients with DCIS or invasive lobular carcinoma (ILC are suitable for APBI. Methods The retrospective cohort included 310 patients with 312 tumors of T1-T2N0-N1micM0 invasive ductal carcinoma (IDC, ILC, or Tis (DCIS treated with APBI via external beam. Most patients were treated using IMRT with 16 daily fractions of 270 cGy to a dose of 4320 cGy. The target volume included the lumpectomy cavity plus 1.0 cm to account for microscopic disease and an additional 0.5 to 1.0 cm for setup uncertainty and breathing motion. Ipsilateral breast failure (IBF was pathologically confirmed as a local failure (LF or an elsewhere failure (EF. Results Median follow-up was 49 months. Among the 312 cases, 213 were IDC, 31 ILC, and 68 DCIS. Median tumor size was 1.0 cm. There were 9 IBFs (2.9% including 5 LFs and 4 EFs. The IBF rates among patients with IDC, ILC, and DCIS were 2.4%, 3.2%, and 4.4%, respectively, with no significant difference between histologies. When patients were analyzed by the ASTRO APBI consensus statement risk groups, 32% of treated cases were considered suitable, 50% cautionary, and 18% unsuitable. The IBF rates among suitable, cautionary, and unsuitable patients were 4.0%, 2.6%, and 1.8%, respectively, with no significant difference between risk groups. Acute skin reactions were rare and long-term cosmetic outcome was very good to excellent. Conclusions External beam APBI with once daily fractionation has a low rate of IBF consistent with other published APBI studies. The ASTRO risk stratification did not

  19. Four years of crusade!

    Directory of Open Access Journals (Sweden)

    Adilson Beatriz

    2012-04-01

    Full Text Available Orbital - The Electronic Journal of Chemistry is entering its 4th year of existence which is a reason to celebrate. A great work has been devoted to preserve a scientific journal of international reputation. This work was not always without mistakes or any trouble. However, these very adversities stimulate additional efforts in order to overcome our errors and, continuing with our serious proposal of editing a journal which scientists from all over the world can submit online their original works manuscripts to be published in peer review and open-access style. Beginning this year, Orbital was classified by the Chemistry Coordination Area on the B5 rank of CAPES Qualis (Brazil and, leveled as B4 by Coordination Areas of Materials and Engineering II. These important details demonstrate that Orbital is progressively attaining the acknowledgment of the Brazilian scientific community. The recognition by CAPES Qualis is crucial as the system evaluates the generation of knowledge in the Brazilian universities and the method by which this same knowledge disseminated to society. Not all these were possible without endeavoring of editors and volunteer assistance of advisors from several national and international institutions. Recently, the young Professors Kleber Thiago de Oliveira (UFSCAR, Grégoire Demetz (USP-RP and Amilcar Machulek Júnior (UFMS have joined us to share the idea and philosophy of Orbital by accepting our invitation to be associated editors. The tasks and challenges are enormous and, we are sure that new participants will support us on the way to achieve indexation in new Databases systems as SCOPUS, ISI and Scielo. Consequently, the international success of this electronic journal will be assured. We sincerely hope that in the academic Brazilian scenario, Orbital can figure as a solid bridge to interchange real creative science that is happening in various locations around the world.

  20. Corneal endothelium after deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus: A four-year comparative study

    Directory of Open Access Journals (Sweden)

    Anil Kubaloglu

    2012-01-01

    Full Text Available Purpose: To compare the status of corneal endothelium and central corneal thickness within the first four postoperative years after deep anterior lamellar keratoplasty (DALK and penetrating keratoplasty (PK in patients with keratoconus. Materials and Methods: Thirty-nine eyes (Group A which had PK and 44 eyes (Group B which had DALK for the treatment of keratoconus were included in this retrospective study. The endothelial cell density (ECD, the mean endothelial cell area and the coefficient of variation of cell area were assessed with a non-contact specular microscope, and the central corneal thickness (CCT was measured with an ultrasound pachymeter. Results: Mean ECD loss rate at two years was 36.24% in Group A and 18.12% in Group B (P<0.001. Mean ECD loss rate at four years was 47.82% in Group A and 21.62% in Group B (P<0.001. Mean annual ECD loss rate was calculated 14.12% per year in Group A and 5.78% per year in Group B. In the PK group, increase in mean CCT was 15.60% in two years and 15.03% in four years, while in the DALK group, mean CCT increased by 8.05% in two years and 9.31% in four years. Conclusions: As the majority of ectatic disorders such as keratoconus occur in young people, long-term endothelial cell survival following treatment with keratoplasty is essential for the long-term visual ability. Our finding that corneal endothelial cell loss in the DALK group occurs at a slower rate than in the PK group suggests DALK as a safer alternative to PK in these selected patients.

  1. LOCAL INTERSTELLAR HYDROGEN'S DISAPPEARANCE AT 1 AU: FOUR YEARS OF IBEX IN THE RISING SOLAR CYCLE

    Energy Technology Data Exchange (ETDEWEB)

    Saul, Lukas; Rodriguez, Diego; Scheer, Juergen; Wurz, Peter [University of Bern, Bern (Switzerland); Bzowski, Maciej; Kubiak, Marzena; Sokol, Justina [Space Research Centre PAS, Warsaw (Poland); Fuselier, Stephen; McComas, Dave [Southwest Research Institute, San Antonio, TX (United States); Moebius, Eberhard [University of New Hampshire, Durham, NH (United States)

    2013-04-20

    NASA's Interstellar Boundary Explorer (IBEX) mission has recently opened a new window on the interstellar medium (ISM) by imaging neutral atoms. One ''bright'' feature in the sky is the interstellar wind flowing into the solar system. Composed of remnants of stellar explosions as well as primordial gas and plasma, the ISM is by no means uniform. The interaction of the local ISM with the solar wind shapes our heliospheric environment with hydrogen being the dominant component of the very local ISM. In this paper, we report on direct sampling of the neutral hydrogen of the local ISM over four years of IBEX observations. The hydrogen wind observed at 1 AU has decreased and nearly disappeared as the solar activity has increased over the last four years; the signal at 1 AU has dropped off in 2012 by a factor of {approx}8 to near background levels. The longitudinal offset has also increased with time presumably due to greater radiation pressure deflecting the interstellar wind. We present longitudinal and latitudinal arrival direction measurements of the bulk flow as measured over four years beginning at near solar minimum conditions. The H distribution we observe at 1 AU is expected to be different from that outside the heliopause due to ionization, photon pressure, gravity, and filtration by interactions with heliospheric plasma populations. These observations provide an important benchmark for modeling of the global heliospheric interaction. Based on these observations we suggest a further course of scientific action to observe neutral hydrogen over a full solar cycle with IBEX.

  2. Searches for Extended and Point-like Neutrino Sources with Four Years of IceCube Data

    DEFF Research Database (Denmark)

    Aartsen, M.G.; Ackermann, M.; Adams, J.

    2014-01-01

    We present results on searches for point-like sources of neutrinos using four years of IceCube data, including the first year of data from the completed 86 string detector. The total livetime of the combined data set is 1373 days. For an E –2 spectrum, the observed 90% C.L. flux upper limits are ...... of active galactic nuclei. In all cases, the data are compatible with the background-only hypothesis, and upper limits on the flux of muon neutrinos are reported for the sources considered....

  3. Using time-on-task measurements to understand student performance in a physics class: A four-year study

    OpenAIRE

    John Stewart; Gay Stewart†; Jennifer Taylor

    2012-01-01

    Student use of out-of-class time was measured for four years in the introductory second-semester calculus-based physics course at the University of Arkansas. Two versions of the course were presented during the time of the measurement. In both versions, the total out-of-class time a student invested in the course explained less than 1% of the variance in test average and in normalized gain on the Conceptual Survey in Electricity and Magnetism. The details of how students used their out-of-cla...

  4. Using time-on-task measurements to understand student performance in a physics class: A four-year study

    OpenAIRE

    John Stewart; Gay Stewart†; Jennifer Taylor

    2012-01-01

    Student use of out-of-class time was measured for four years in the introductory second-semester calculus-based physics course at the University of Arkansas. Two versions of the course were presented during the time of the measurement. In both versions, the total out-of-class time a student invested in the course explained less than 1% of the variance in test average and in normalized gain on the Conceptual Survey in Electricity and Magnetism. The details of how students used their out-of-cla...

  5. Extension of general practice training from three to four years: experiences of a vocational training programme in Southern Ireland.

    LENUS (Irish Health Repository)

    Dowling, Stephanie

    2009-05-01

    The aim of this study was to evaluate the experiences of trainees taking part in an extended (four-year) general practice training programme introduced in the South Eastern region of the Republic of Ireland to replace the previous traditional (three-year) programme. In a qualitative design, eight homogeneous focus groups were held to determine the value of the additional year of training. The first cohort of trainees was interviewed towards the start and at the end of their fourth year. Trainees finishing the following year were also interviewed, as were graduates from the final three-year programme. GP trainers and the four members of the programme directing team comprised two further independent focus groups. Trainees reported that the integration of hospital posts and general practice attachments over the four years was particularly beneficial. The exposure to a variety of different general practices and the opportunity to take part in specialty clinics were considered extremely useful. The fourth year of training was felt to be less pressurised than previous years. Professional and personal development was enhanced; improved readiness to practise and confidence were noted. Perceived disadvantages of extended training included a lack of acknowledgment for doctors in their fourth year and excessive emphasis placed on research during the final year of training. The addition of an extra year of vocational training improves professional and personal development and changes the learning experience for doctors. Doctors felt more confident and ready to enter independent practice at the end of the fourth year of training.

  6. Population profiles associated with severe functioning difficulties and disability among two to four years old children in Mexico

    Directory of Open Access Journals (Sweden)

    Rosalba Rojas-Martínez

    2017-07-01

    Full Text Available Objective. To describe the prevalence and factors associated with severe child functioning difficulties and disability (CFD among two to four year old children in Mexico, and estimates the probability of presenting CFD based on specific population profiles. Materials and methods. The sample consists of 5 104 children who participated in the National Survey of Children and Women 2015 (ENIM. We used postestimation exploration by computing predicted values of CFD to interpret the logistic models for discrete combinations of the independent variables. Results. CFD prevalence is 2%,which means at least 130 000 two to four year-old children are at risk of experiencing severely limited participation in an unaccommodating environment. The probability of presenting CFD is dramatically higher in specific sub-groups of the population, in particular, male children of women with low education, who live in the poorest households. Conclusions. A significant proportion of Mexican children face important challenges due to functioning difficulties and disability. Public policies must be developed to accommodate the needs of these children and provide a proper environment for their development.

  7. Where to find a trustworthy source of information? four years of risk communication about a nuclear waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Findahl, O. [Dept. of Media and Communication, Umea University, Umea (Sweden)

    1998-07-01

    Full text of publication follows: in September 1997 there was a referendum, in a small local district in the north of Sweden, on the disposal of the swedish high intensive nuclear waste. A small majority of the 2500 voters stopped the examination of the conditions for a storage. Four years earlier the opinionagainst a local storage of nuclear waste had been much stronger but during the years that followed more people came to think that an examination of the conditions for a storage was OK; that will create new jobs, and what will come later we will see. The closer to the referendum the stronger this positive opinion became. They did not have any information problems. There were experts and information sources they could believe in. But the majority was still negative and they were dissatisfied. They could not find any trustworthy information. And though they in the end had prevented the localization of the nuclear waste storage to their commune they still felt that the decision had been taken high above their heads. Why is it like that? And what happened during these four years of experimentation in democratic risk communication? (author)

  8. Do postoperative radiographically verified technical success, improved cosmesis, and trunk shift corroborate with patient-reported outcomes in Lenke 1C adolescent idiopathic scoliosis?

    Science.gov (United States)

    Sharma, Shallu; Bünger, Cody Eric; Andersen, Thomas; Sun, Haolin; Wu, Chunsen; Hansen, Ebbe Stender

    2015-07-01

    To examine correlation between postoperative radiographic and cosmetic improvements in Lenke 1C adolescent idiopathic scoliosis (AIS) with patients' self-rated outcomes of health and disability at follow-up as determined by the Scoliosis Research Society questionnaire (SRS-30), Oswestry Disability Index score (ODI) and measure of overall health quality Euroqol-5d (EQ-5D). 24 Lenke 1C scoliosis patients, mean age 16.5 (12.8-38.1) years, treated with posterior pedicle screw-only construct, were included. The coronal profile indices (radiographic and cosmetic) regarding magnitude of spinal deformity and truncal balance were measured preoperatively, postoperatively and at final follow-up. A comprehensive index of overall back symmetry was also measured by means of the Posterior Trunk Symmetry Index (POTSI). Pearson's correlation analysis determined the association between the radiographic-cosmetic indices and patient-rated outcomes. Mean follow-up for the cohort was 4.4 (±1.86) years. The thoracic apical vertebra-first thoracic vertebra horizontal distance (AV-TI) correction had significant correlation with function, self-image, and mental health SRS-30 scores (0.55, 0.54, 0.66). Similarly, thoracic apical vertebra horizontal translation from central sacral vertical line (AV-CSVL) correction at follow-up had significant correlation with self-image and management domains (0.57, 0.50). Follow-up POTSI correlated well with SRS-30 and EQ-5D scores (r = -0.64, -0.54). Postoperative leftward trunk shift/spinal imbalance did not influence overall cosmesis and outcomes; significant spinal realignment was evident in follow-up resulting in physiological balance and acceptable cosmesis and outcomes. Significant, but less than "perfect" correlations were observed between the radiographic, cosmetic measures and patient-rated outcomes. Thoracic AV-CSVL, AV-T1 correction and POTSI associated significantly with SRS-30 scores. Whereas, thoracic Cobb angle, Cobb correction, and

  9. Overweight at four years of age in a Swedish birth cohort: influence of neighbourhood-level purchasing power.

    Science.gov (United States)

    Roswall, Josefine; Almqvist-Tangen, Gerd; Holmén, Anders; Alm, Bernt; Bergman, Stefan; Dahlgren, Jovanna; Strömberg, Ulf

    2016-07-11

    A number of child/parental factors have been shown to be significant predictors of childhood overweight, although a better understanding of possible contextual influences of neighbourhood-level characteristics might provide new insights leading to tailored, targeted interventions. The aim of this study was to explore the impact of neighbourhood purchasing power and its relationship with other known risk factors related to childhood overweight in a prospective birth cohort. A prospective, population-based, birth-cohort study was conducted in south-western Sweden, comprising 2,666 infants born in 2007-2008. Childhood overweight was assessed by body mass index (BMI) data from follow-up examinations at four years of age (n = 2,026) and overweight defined according to the International Obesity Task Force. Using logistic regression analysis, the influential child/parental predictors were identified from the candidate predictors, viz. child's gender, as well as birth weight adjusted for gestational age and parental factors at recruitment, including maternal smoking status, maternal BMI (before pregnancy), paternal BMI and parental educational level. The children's residential parishes at follow-up were stratified by parish-level household purchasing power (purchasing power) and the "contextual" influence was analysed. In each such neighbourhood stratum, the adjusted overweight ratio (AOR), i.e. the ratio between the observed number of overweight children and the expected number, taking account of the influential child/parental predictors, was estimated. The prevalence of overweight at four years of age was 11.9 %. In the economically strongest neighbourhoods (i.e. purchasing power), the AOR was 0.60 (95 % confidence interval (CI): 0.34-0.98). The corresponding empirically Bayes-adjusted AOR was 0.73 (95 % CI: 0.46-1.02; 97 % posterior probability of AOR <1). In the other neighbourhood strata, the statistical evidence of a deviant AOR was weaker. The economically

  10. Recovery of a subtropical rocky shore is not yet complete, four years after a moderate sized oil spill.

    Science.gov (United States)

    Finlayson, Kimberly; Stevens, Tim; Arthur, James Michael; Rissik, David

    2015-04-15

    Little is known about the recovery trajectory from small to moderate spills (rocky shores. This study examines the recovery of the rocky shore community four years after the spill. Results indicate that recovery on Moreton Island is taking longer than the 3-4 years suggested by the literature. The upper shore is recovering faster than the mid shore and is nearly recovered while the mid shore is still in the recovery process. These results indicate that small to moderate sized spills can have environmental impacts on par with much larger spills and emphasizes the need for a clear definition of a recovery endpoint. Long term studies are required to gain a full understanding of trajectories of recovery after oil spill impacts.

  11. Species Diversity Effects on Productivity, Persistence and Quality of Multispecies Swards in a Four-Year Experiment

    DEFF Research Database (Denmark)

    Jing, Jingying; Søegaard, Karen; Cong, Wen-Feng

    2017-01-01

    Plant species diversity may benefit natural grassland productivity, but its effect in managed grassland systems is not well understood. A four-year multispecies grassland experiment was conducted to investigate the effect of species diversity±legumes and non-leguminous forbs±on productivity......, persistence and sward quality under cutting or grazing regimes and with or without slurry application. Three mixtures were established± 3-mix: grass, red and white clover, 10-mix: 3-mix plus birdsfoot trefoil and six non-leguminous forbs, and 12-mix: 10-mix plus lucerne and festulolium. Species diversity...... to cutting, grazing increased forage production by 9% per cut on average and lowered legume and forb proportions in the mixtures, but yields did not differ among the three mixtures. Overall, our results suggest that species diversity increases sward productivity and persistence only under an ungrazed cutting...

  12. The national neonatal screening programme for congenital toxoplasmosis in Denmark: results from the initial four years, 1999-2002

    DEFF Research Database (Denmark)

    Schmidt, Dorte Remmer; Høgh, Birthe; Andersen, O;

    2006-01-01

    AIMS: To describe the outcome of four years' nationwide neonatal screening for congenital toxoplasmosis in liveborn newborns. METHODS: Congenital toxoplasmosis was diagnosed if specific Toxoplasma gondii IgM antibodies were detected in eluate from the PKU Guthrie filter paper card from a child....... Infants diagnosed with congenital toxoplasmosis were examined for intracranial and retinal lesions and treated for three months with sulphadiazine, pyrimethamine, and folinic acid continuously. RESULTS: Eluates from PKU-cards from 262 912 newborns were analysed. The birth prevalence of congenital...... toxoplasma infection was 2.1 per 10 000 liveborns. Congenital toxoplasmosis was suspected in 96 infants and confirmed in 55. Forty seven children were examined for intracranial and retinal lesions soon after birth; 12 had clinical signs at this first examination. Of these, 5 had intracranial calcifications...

  13. Mammary tumors and serum hormones in the bitch treated with medroxyprogesterone acetate or progesterone for four years

    Energy Technology Data Exchange (ETDEWEB)

    Frank, D.W.; Kirton, K.T.; Murchison, T.E.; Quinlan, W.J.; Coleman, M.E.; Gilbertson, T.J.; Feenstra, E.S.; Kimball, F.A.

    1978-01-01

    After four years of a long term contraceptive steroid safety study, the incidence and the histologic type of mammary dysplasia produced is similar in beagles treated with medroxyprogesterone acetate (medroxyprogesterone) or progesterone. Serum insulin, thyroid stimulating hormone (TSH), triiodothyronine, growth hormone, prolactin, 17..beta..-estradiol, progesterone, and cortisol were determined by radioimmunoassay on samples collected after 45 months of treatment. Serum growth hormone and insulin concentrations were elevated in a dose related manner in both treatment groups. Triiodothyronine, cortisol, and estradiol-17..beta.. (medroxyprogesterone only) were lowered. TSH and prolactin concentrations were not changed. Pituitary--gonadal hormone interaction in the pathogenesis of mammary neoplasia of the dog is discussed. Prolonged treatment of the beagle with massive doses of progesterone or medroxyprogesterone results in a dose related incidence of mammary modules.

  14. Antimicrobial use over a four-year period using days of therapy measurement at a Canadian pediatric acute care hospital

    Science.gov (United States)

    Dalton, Bruce R; MacTavish, Sandra J; Bresee, Lauren C; Rajapakse, Nipunie; Vanderkooi, Otto; Vayalumkal, Joseph; Conly, John

    2015-01-01

    BACKGROUND: Antimicrobial resistance is a concern that is challenging the ability to treat common infections. Surveillance of antimicrobial use in pediatric acute care institutions is complicated because the common metric unit, the defined daily dose, is problematic for this population. OBJECTIVE: During a four-year period in which no specific antimicrobial stewardship initiatives were conducted, pediatric antimicrobial use was quantified using days of therapy (DOT) per 100 patient days (PD) (DOT/100 PD) at the Alberta Children’s Hospital (Calgary, Alberta) for benchmarking purposes. METHODS: Drug use data for systemic antimicrobials administered on wards at the Alberta Children’s Hospital were collected from electronic medication administration records. DOT were calculated and rates were determined using 100 PD as the denominator. Changes over the surveillance period and subgroup proportions were represented graphically and assessed using linear regression. RESULTS: Total antimicrobial use decreased from 93.6 DOT/100 PD to 75.7 DOT/100 PD (19.1%) over the 2010/2011 through to the 2013/2014 fiscal years. During this period, a 20.0% increase in PD and an essentially stable absolute count of DOT (2.9% decrease) were observed. Overall, antimicrobial use was highest in the pediatric intensive care and oncology units. DISCUSSION: The exact changes in prescribing patterns that led to the observed reduction in DOT/100 PD with associated increased PD are unclear, but may be a topic for future investigations. CONCLUSION: Antimicrobial use data from a Canadian acute care pediatric hospital reported in DOT/100 PD were compiled for a four-year time period. These data may be useful for benchmarking purposes. PMID:26600813

  15. Species Diversity Effects on Productivity, Persistence and Quality of Multispecies Swards in a Four-Year Experiment

    Science.gov (United States)

    Søegaard, Karen; Cong, Wen-Feng; Eriksen, Jørgen

    2017-01-01

    Plant species diversity may benefit natural grassland productivity, but its effect in managed grassland systems is not well understood. A four-year multispecies grassland experiment was conducted to investigate the effect of species diversity–legumes and non-leguminous forbs–on productivity, persistence and sward quality under cutting or grazing regimes and with or without slurry application. Three mixtures were established– 3-mix: grass, red and white clover, 10-mix: 3-mix plus birdsfoot trefoil and six non-leguminous forbs, and 12-mix: 10-mix plus lucerne and festulolium. Species diversity increased sward production and yield persistence under cutting regime. The 12-mix had the highest yield from the second year onwards and no statistically significant yield reduction over four years, while annual yields in the 3-mix and 10-mix decreased significantly with increasing grassland age. The higher yield in the 12-mix was mainly due to the inclusion of high-yielding lucerne. The 10-mix and 12-mix had lower proportions of unsown species than the 3-mix, the difference being dependent on grassland age. Generally, the 3-mix had higher concentrations of in-vitro organic matter digestibility (IVOMD), neutral detergent fiber (NDF) and crude protein (CP), and a lower concentration of ash than the 10-mix and 12-mix. Slurry application increased annual yield production by 10% and changed the botanical composition, increasing the proportion of grass and decreasing the proportion of legumes. Compared to cutting, grazing increased forage production by 9% per cut on average and lowered legume and forb proportions in the mixtures, but yields did not differ among the three mixtures. Overall, our results suggest that species diversity increases sward productivity and persistence only under an ungrazed cutting regime. We conclude that increasing species diversity by selecting appropriate species with compatible management is key to achieving both high yields and high persistence

  16. The impact of tenofovir disoproxil fumarate on kidney function: four-year data from the HIV-infected outpatient cohort

    Directory of Open Access Journals (Sweden)

    Nadine Monteiro

    2014-11-01

    Full Text Available Introduction: With improvements in survival and disease progression in the era of combined antiretroviral therapy, complications such as kidney disease are becoming increasingly prevalent in HIV-infected patients. Tenofovir disoproxil fumarate (TDF has been associated with nephrotoxicity, including decline in glomerular filtration rate, proximal tubular damage and acute kidney injury. Objective: Characterize kidney safety of TDF-containing antiretroviral treatment (ART regimens in HIV-infected patients. Methods: Non-controlled, observational, retrospective study was based on the clinical files registry of HIV patients who started TDF between January and December 2008. We assessed outpatients followed at a single Portuguese center. Demographic, clinical, virological and immunological data at baseline were collected. Serum creatinine, estimated glomerular filtration rate (eGFR and creatinine clearance (CrCL were assessed at baseline, after six months and every year up to four years. CrCL and eGFR were calculated by Cockroft–Gault and Modification of Diet in Renal Disease equations, respectively. Results: A total of 176 patients (71.6% males with a mean age of 43 years were enrolled. Ninety-six (52% were ART-naive patients at TDF initiation. At baseline 12.5% had hypertension, 4% diabetes, 25% chronic hepatitis C and 9% chronic hepatitis B infections; 58% had normal renal function (eGFR ≥90 ml/min/1.73 m2, 36% had mild (eGFR 60-89 ml/min/1.73 m2 renal dysfunction and 2.3% had moderate (eGFR 30-59 ml/min/1.73 m2 renal dysfunction at initiation of TDF. Eighty-three (47% patients were on protease inhibitors and the remaining on NNRTIs containing regimens. During 48 months follow-up, 5% experienced moderate renal dysfunction and 1.7% severe renal dysfunction. Twenty-one (12% patients met the definition criteria of rapid decline of renal function (annual decline of eGFR ≥3 ml/min/1.73 m2 in two consecutive years. The development of kidney events

  17. Searches for extended and point-like neutrino sources with four years of IceCube data

    Energy Technology Data Exchange (ETDEWEB)

    Aartsen, M. G. [School of Chemistry and Physics, University of Adelaide, Adelaide SA, 5005 Australia (Australia); Ackermann, M.; Berghaus, P. [DESY, D-15735 Zeuthen (Germany); Adams, J. [Department of Physics and Astronomy, University of Canterbury, Private Bag 4800, Christchurch (New Zealand); Aguilar, J. A. [Département de physique Nucléaire et Corpusculaire, Université de Genève, CH-1211 Genève (Switzerland); Ahlers, M.; Arguelles, C.; BenZvi, S. [Department of Physics and Wisconsin IceCube Particle Astrophysics Center, University of Wisconsin, Madison, WI 53706 (United States); Ahrens, M. [Oskar Klein Centre and Department of Physics, Stockholm University, SE-10691 Stockholm (Sweden); Altmann, D. [Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91058 Erlangen (Germany); Anderson, T.; Arlen, T. C. [Department of Physics, Pennsylvania State University, University Park, PA 16802 (United States); Auffenberg, J. [III. Physikalisches Institut, RWTH Aachen University, D-52056 Aachen (Germany); Bai, X. [Physics Department, South Dakota School of Mines and Technology, Rapid City, SD 57701 (United States); Barwick, S. W. [Department of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Baum, V. [Institute of Physics, University of Mainz, Staudinger Weg 7, D-55099 Mainz (Germany); Beatty, J. J. [Department of Physics and Center for Cosmology and Astro-Particle Physics, Ohio State University, Columbus, OH 43210 (United States); Tjus, J. Becker [Fakultät für Physik and Astronomie, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Becker, K.-H. [Department of Physics, University of Wuppertal, D-42119 Wuppertal (Germany); Berley, D. [Department of Physics, University of Maryland, College Park, MD 20742 (United States); Collaboration: IceCube Collaboration; and others

    2014-12-01

    We present results on searches for point-like sources of neutrinos using four years of IceCube data, including the first year of data from the completed 86 string detector. The total livetime of the combined data set is 1373 days. For an E {sup –2} spectrum, the observed 90% C.L. flux upper limits are ∼10{sup –12} TeV{sup –1} cm{sup –2} s{sup –1} for energies between 1 TeV and 1 PeV in the northern sky and ∼10{sup –11} TeV{sup –1} cm{sup –2} s{sup –1} for energies between 100 TeV and 100 PeV in the southern sky. This represents a 40% improvement compared to previous publications, resulting from both the additional year of data and the introduction of improved reconstructions. In addition, we present the first results from an all-sky search for extended sources of neutrinos. We update the results of searches for neutrino emission from stacked catalogs of sources and test five new catalogs; two of Galactic supernova remnants and three of active galactic nuclei. In all cases, the data are compatible with the background-only hypothesis, and upper limits on the flux of muon neutrinos are reported for the sources considered.

  18. Sex difference in response to stress by lunar month: A pilot study of four years' crisis-call frequency

    Directory of Open Access Journals (Sweden)

    Steffert Beverly

    2003-12-01

    Full Text Available Abstract Background This study is in response to the question of whether the moon can influence daily levels of stress. Method Four years of telephone-call frequency data were obtained from a single crisis-call centre. We used the method of lunar-day numbers 1 to 29 for analysis. We also tested the concept of 'strong moons' as occurring when the Sun was near to the lunar-node axis. Results An increase in calls was recorded from females and a decrease in calls by males during the new moon period, suggesting a sex difference in response, and there were proportionally more calls by males a fortnight later. A comparable swing in the male/female call-ratio on a weekly basis over Fridays and Saturdays was noted. Limitations of staffing at the call-centre prohibited comment on seasonal correlations. Conclusion Lunar-related studies of stress should endeavour to separate the data by sex or the effect can be lost. Distress-calls by women were more strongly linked to the lunar month than were those by men.

  19. Using time-on-task measurements to understand student performance in a physics class: A four-year study

    Directory of Open Access Journals (Sweden)

    John Stewart*

    2012-04-01

    Full Text Available Student use of out-of-class time was measured for four years in the introductory second-semester calculus-based physics course at the University of Arkansas. Two versions of the course were presented during the time of the measurement. In both versions, the total out-of-class time a student invested in the course explained less than 1% of the variance in test average and in normalized gain on the Conceptual Survey in Electricity and Magnetism. The details of how students used their out-of-class time explained from 21% to 36% of the variance in test average and 19% to 37% of the variance in normalized gain. The amount of time spent on the course increased as the course was made more difficult, but less than would be expected based on the changes in the course. Students changed their allocation of out-of-class time based on their performance within the course as the course progressed.

  20. Integrating critical thinking and evidence-based dentistry across a four-year dental curriculum: a model for independent learning.

    Science.gov (United States)

    Marshall, Teresa A; Straub-Morarend, Cheryl L; Handoo, Nidhi; Solow, Catherine M; Cunningham-Ford, Marsha A; Finkelstein, Michael W

    2014-03-01

    Introducing critical thinking and evidence-based dentistry (EBD) content into an established dental curriculum can be a difficult and challenging process. Over the past three years, the University of Iowa College of Dentistry has developed and implemented a progressive four-year integrated critical thinking and EBD curriculum. The objective of this article is to describe the development and implementation process to make it available as a model for other dental schools contemplating introduction of critical thinking and EBD into their curricula. The newly designed curriculum built upon an existing problem-based learning foundation, which introduces critical thinking and the scientific literature in the D1 year, in order to expose students to the rationale and resources for practicing EBD in the D2 and D3 years and provide opportunities to practice critical thinking and apply the EBD five-step process in the D2, D3, and D4 years. All curricular content is online, and D3 and D4 EBD activities are integrated within existing clinical responsibilities. The curricular content, student resources, and student activities are described.

  1. Searches for Extended and Point-like Neutrino Sources with Four Years of IceCube Data

    CERN Document Server

    Aartsen, M G; Adams, J; Aguilar, J A; Ahlers, M; Ahrens, M; Altmann, D; Anderson, T; Arguelles, C; Arlen, T C; Auffenberg, J; Bai, X; Barwick, S W; Baum, V; Beatty, J J; Tjus, J Becker; Becker, K -H; BenZvi, S; Berghaus, P; Berley, D; Bernardini, E; Bernhard, A; Besson, D Z; Binder, G; Bindig, D; Bissok, M; Blaufuss, E; Blumenthal, J; Boersma, D J; Bohm, C; Bos, F; Bose, D; Böser, S; Botner, O; Brayeur, L; Bretz, H -P; Brown, A M; Casey, J; Casier, M; Cheung, E; Chirkin, D; Christov, A; Christy, B; Clark, K; Classen, L; Clevermann, F; Coenders, S; Cowen, D F; Silva, A H Cruz; Danninger, M; Daughhetee, J; Davis, J C; Day, M; de André, J P A M; De Clercq, C; De Ridder, S; Desiati, P; de Vries, K D; de With, M; DeYoung, T; Díaz-Vélez, J C; Dunkman, M; Eagan, R; Eberhardt, B; Eichmann, B; Eisch, J; Euler, S; Evenson, P A; Fadiran, O; Fazely, A R; Fedynitch, A; Feintzeig, J; Felde, J; Feusels, T; Filimonov, K; Finley, C; Fischer-Wasels, T; Flis, S; Franckowiak, A; Frantzen, K; Fuchs, T; Gaisser, T K; Gallagher, J; Gerhardt, L; Gier, D; Gladstone, L; Glüsenkamp, T; Goldschmidt, A; Golup, G; Gonzalez, J G; Goodman, J A; Góra, D; Grandmont, D T; Grant, D; Gretskov, P; Groh, J C; Groß, A; Ha, C; Haack, C; Ismail, A Haj; Hallen, P; Hallgren, A; Halzen, F; Hanson, K; Hebecker, D; Heereman, D; Heinen, D; Helbing, K; Hellauer, R; Hellwig, D; Hickford, S; Hill, G C; Hoffman, K D; Hoffmann, R; Homeier, A; Hoshina, K; Huang, F; Huelsnitz, W; Hulth, P O; Hultqvist, K; Hussain, S; Ishihara, A; Jacobi, E; Jacobsen, J; Jagielski, K; Japaridze, G S; Jero, K; Jlelati, O; Jurkovic, M; Kaminsky, B; Kappes, A; Karg, T; Karle, A; Kauer, M; Kelley, J L; Kheirandish, A; Kiryluk, J; Kläs, J; Klein, S R; Köhne, J -H; Kohnen, G; Kolanoski, H; Koob, A; Köpke, L; Kopper, C; Kopper, S; Koskinen, D J; Kowalski, M; Kriesten, A; Krings, K; Kroll, G; Kroll, M; Kunnen, J; Kurahashi, N; Kuwabara, T; Labare, M; Larsen, D T; Larson, M J; Lesiak-Bzdak, M; Leuermann, M; Leute, J; Lünemann, J; Macías, O; Madsen, J; Maggi, G; Maruyama, R; Mase, K; Matis, H S; Maunu, R; McNally, F; Meagher, K; Medici, M; Meli, A; Meures, T; Miarecki, S; Middell, E; Middlemas, E; Milke, N; Miller, J; Mohrmann, L; Montaruli, T; Morse, R; Nahnhauer, R; Naumann, U; Niederhausen, H; Nowicki, S C; Nygren, D R; Obertacke, A; Odrowski, S; Olivas, A; Omairat, A; O'Murchadha, A; Palczewski, T; Paul, L; Penek, Ö; Pepper, J A; Heros, C Pérez de los; Pfendner, C; Pieloth, D; Pinat, E; Posselt, J; Price, P B; Przybylski, G T; Pütz, J; Quinnan, M; Rädel, L; Rameez, M; Rawlins, K; Redl, P; Rees, I; Reimann, R; Resconi, E; Rhode, W; Richman, M; Riedel, B; Robertson, S; Rodrigues, J P; Rongen, M; Rott, C; Ruhe, T; Ruzybayev, B; Ryckbosch, D; Saba, S M; Sander, H -G; Sandroos, J; Santander, M; Sarkar, S; Schatto, K; Scheriau, F; Schmidt, T; Schmitz, M; Schoenen, S; Schöneberg, S; Schönwald, A; Schukraft, A; Schulte, L; Schulz, O; Seckel, D; Sestayo, Y; Seunarine, S; Shanidze, R; Sheremata, C; Smith, M W E; Soldin, D; Spiczak, G M; Spiering, C; Stamatikos, M; Stanev, T; Stanisha, N A; Stasik, A; Stezelberger, T; Stokstad, R G; Stößl, A; Strahler, E A; Ström, R; Strotjohann, N L; Sullivan, G W; Taavola, H; Taboada, I; Tamburro, A; Tepe, A; Ter-Antonyan, S; Terliuk, A; Tešić, G; Tilav, S; Toale, P A; Tobin, M N; Tosi, D; Tselengidou, M; Unger, E; Usner, M; Vallecorsa, S; van Eijndhoven, N; Vandenbroucke, J; van Santen, J; Vehring, M; Voge, M; Vraeghe, M; Walck, C; Wallraff, M; Weaver, Ch; Wellons, M; Wendt, C; Westerhoff, S; Whelan, B J; Whitehorn, N; Wichary, C; Wiebe, K; Wiebusch, C H; Williams, D R; Wissing, H; Wolf, M; Wood, T R; Woschnagg, K; Xu, D L; Xu, X W; Yanez, J P; Yodh, G; Yoshida, S; Zarzhitsky, P; Ziemann, J; Zierke, S; Zoll, M

    2014-01-01

    We present results on searches for point-like sources of neutrinos using four years of IceCube data, including the first year of data from the completed 86-string detector. The total livetime of the combined dataset is 1,373 days. For an E$^{-2}$ spectrum the median sensitivity at 90\\% C.L. is $\\sim 10^{-12}$ TeV$^{-1}$cm$^{-2}$s$^{-1}$ for energies between 1 TeV$-$1 PeV in the northern sky and $\\sim 10^{-11}$ TeV$^{-1}$cm$^{-2}$s$^{-1}$ for energies between 100 TeV $-$ 100 PeV in the southern sky. The sensitivity has improved from both the additional year of data and the introduction of improved reconstructions compared to previous publications. In addition, we present the first results from an all-sky search for extended sources of neutrinos. We update results of searches for neutrino emission from stacked catalogs of sources, and test five new catalogs; two of Galactic supernova remnants and three of active galactic nuclei. In all cases, the data are compatible with the background-only hypothesis, and uppe...

  2. Peripheral Giant Cell Granuloma in a Child Associated with Ectopic Eruption and Traumatic Habit with Control of Four Years

    Science.gov (United States)

    Leite, Cristhiane Almeida; Anhesini, Brunna Haddad; Aguilera, Jéssica Marques Gomes da Silva

    2016-01-01

    Peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion that may affect any region of the gingiva or alveolar mucosa of edentulous and toothed areas, preferentially in the mandible and rarely occurring in children. This report describes the clinical and histopathological findings of a PGCG diagnosed in the maxilla of a 9-year-old boy associated with a tooth erupting improperly and a traumatic habit. The patient did not present anything noteworthy on extraoral physical examination or medical history, but the habit of picking his teeth and “poking” the gingiva. The oral lesion consisted of an asymptomatic, rounded, pink colored, smooth surface, soft tissue injury with fibrous consistency and approximated size of 1.5 cm located in the attached gingiva between the upper left permanent lateral incisor and the primary canine of the same side. Excisional biopsy was performed through curettage and removal of the periosteum, periodontal ligament, and curettage of the involved teeth with vestibular access. The histopathological analysis led to the diagnosis of PGCG. The prompt diagnosis and treatment of the PGCG resulted in a more conservative surgery and a reduced risk for tooth and bone loss and recurrence of the lesion. After four years of control, patient had no relapse of the lesion and good gingival and osseous health. PMID:27999690

  3. User feedback on the MSF tele-expertise service after a four-year pilot trial –- a comprehensive analysis

    Directory of Open Access Journals (Sweden)

    Laurent eBONNARDOT

    2015-11-01

    Full Text Available We surveyed all users of the MSF tele-expertise service, approximately four years after it began operation. The survey contained 50 questions and was sent to 294 referrers and 254 specialists. There were 163 responses (response rate 30%. There were no significant differences between the responses from French and English users, so the responses were combined for subsequent analysis. Most of the responders were doctors (133 of 157 who answered that question, and most had completed field missions for MSF, i.e. both specialists and referrers. The majority stated that the system was user-friendly, and that they found it self-explanatory (i.e. they did not need to be shown how to use it. Almost all the referrers found that the telemedicine advice they received was helpful, and changed diagnosis, management and/or reassured the patient. Similar feedback came from the specialists, who also felt that there was educational value for the field doctor. Although there was general satisfaction with the service, the survey identified various problems. The main concerns -- raised by referrers was the lack of promotion of system at headquarters' level, and for specialists, the lack of feedback about patient follow up. Nonetheless, both referrers and specialists recognised the benefits of telemedicine in improving patient management, the provision of education and the reduction of isolation in the field.

  4. Site-growth relationship of different short-rotation coppice tree species in southwestern Germany four years after establishment

    Directory of Open Access Journals (Sweden)

    Kristin Nerlich

    2016-01-01

    Full Text Available Due to lack of detailed information on the suitability of short rotation coppice (SRC species for different climatic regions, over four years this study investigated tree growth and susceptibility to pests and diseases of willow (Salix spp. and poplar (Populus spp. clones and other tree species like Alnus spp. and Robinia pseudoacacia at four sites located in southwestern Germany. The study was undertaken in order to deduce the kind of tree species recommended for the various site conditions. In 2009, field trials were established at four sites which differ in climate and soil characteristics (Forchheim, Kupferzell, Marbach and Aulendorf. At all tested locations, a high survival rate (>90 % was observed for almost all willow and poplar clones and little infestations with leaf rust (Melampsora and minor leaf damages caused by the poplar leaf beetle (Chrysomela populi had occurred. The survival of the other tree species varied from 22 to 97 % depending on the site and species. Across all tree species and locations, results indicated that willow clones can be recommended for cold sites and poplars generally seem to require higher temperatures. The Alnus spp. seems to be favorable for both cold and warm conditions while Robinia pseudoacacia can be recommended for warm sites. Due to its chilling sensitivity, Paulownia tomentosa seems to be rather unsuitable for cultivation in southwestern Germany. For all tested sites, it appears that those with heavy soils and dry conditions are inappropriate for establishing SRC species.

  5. Peripheral Giant Cell Granuloma in a Child Associated with Ectopic Eruption and Traumatic Habit with Control of Four Years

    Directory of Open Access Journals (Sweden)

    Luiz Evaristo Ricci Volpato

    2016-01-01

    Full Text Available Peripheral giant cell granuloma (PGCG is a nonneoplastic lesion that may affect any region of the gingiva or alveolar mucosa of edentulous and toothed areas, preferentially in the mandible and rarely occurring in children. This report describes the clinical and histopathological findings of a PGCG diagnosed in the maxilla of a 9-year-old boy associated with a tooth erupting improperly and a traumatic habit. The patient did not present anything noteworthy on extraoral physical examination or medical history, but the habit of picking his teeth and “poking” the gingiva. The oral lesion consisted of an asymptomatic, rounded, pink colored, smooth surface, soft tissue injury with fibrous consistency and approximated size of 1.5 cm located in the attached gingiva between the upper left permanent lateral incisor and the primary canine of the same side. Excisional biopsy was performed through curettage and removal of the periosteum, periodontal ligament, and curettage of the involved teeth with vestibular access. The histopathological analysis led to the diagnosis of PGCG. The prompt diagnosis and treatment of the PGCG resulted in a more conservative surgery and a reduced risk for tooth and bone loss and recurrence of the lesion. After four years of control, patient had no relapse of the lesion and good gingival and osseous health.

  6. Lessons learned from four years of actively using River Forecast Center Ensemble Streamflow Predictions to inform reservoir management

    Science.gov (United States)

    Polebitski, A.; Palmer, R.; Meaker, B.

    2012-12-01

    The National Weather Service's River Forecast Centers (RFCs), located throughout the US, produce operational streamflow forecasts for short term application and long-term lead forecasts at selected locations. These forecasts are targeted for a variety of users, including water supply management, flood control, hydropower production, navigation, and recreation. This presentation highlights the challenges and successes associated with the use of RFC produced ensemble streamflow predictions (ESP) in generating system operations forecasts over the past four years for Snohomish County Public Utility District #1's (SnoPUD) Henry Jackson hydropower system. This research documents a multiyear collaboration between SnoPUD and academic researchers. The collaboration began with a proof of concept study in 2007 and evolved into a weekly decision support activity that has been ongoing since 2008 ( documented in Alemu et al. 2010). The Alemu et al. paper demonstrates the usefulness of ESP forecasts in hydropower operations decision making. This paper focuses on the value of forecasts and a decision support system (DSS) in improving skills in operating reservoir systems. During the application period, the model provided weekly guidance on meeting operational objectives and a probabilistic approach to quantifying system vulnerability during critical periods such as floods and drought. The ESP forecasts and the DSS were heavily used during periods of uncertainty and less so during periods of high system constraint or low system risk.

  7. Student Perceptions of Staged Transfer to Independent Research Skills during a Four-Year Honours Science Undergraduate Program

    Science.gov (United States)

    Symons, Sarah L.; Colgoni, Andrew; Harvey, Chad T.

    2017-01-01

    We describe interim results of an ongoing longitudinal pedagogical study investigating the efficacy of the Honours Integrated Science Program (iSci). We describe the pedagogical methods we use to prompt research skill development in a model from instructor-dependence to independent original research. We also describe a tool we use to help students…

  8. Accelerated partial-breast irradiation vs conventional whole-breast radiotherapy in early breast cancer: A case-control study of disease control, cosmesis, and complications

    Directory of Open Access Journals (Sweden)

    Wadasadawala Tabassum

    2009-01-01

    Full Text Available Context: Accelerated partial-breast irradiation (APBI using various approaches is being increasingly employed for selected women with early breast cancer (EBC. Aims: To conduct a case-control study comparing disease control, cosmesis, and complications in patients with EBC undergoing APBI using multicatheter interstitial brachytherapy vs those receiving conventional whole breast radiotherapy (WBRT. Settings and Design: Women with EBC fulfilling the American Brachytherapy Society (ABS criteria were selected as ′cases′ if treated with APBI or as ′controls′ if offered WBRT during the period from May 2000 to December 2004. Materials and Methods: APBI patients were treated with high-dose-rate brachytherapy (HDR to a dose of 34 Gy/10#/6-8 days. WBRT was delivered to the whole breast to a dose of 45 Gy/25# followed by tumor bed boost, either with electrons (15 Gy/6# or interstitial brachytherapy (HDR 10 Gy/1#. Results: At the median follow-up of 43.05 months in APBI and 51.08 months in WBRT there was no difference in overall survival (OS, disease-free survival (DFS, late arm edema, and symptomatic fat necrosis between the two groups. However, APBI resulted in increase in mild breast fibrosis at the tumor bed. Telangiectasias were observed in three patients of the APBI group. The cosmetic outcome was significantly better in the APBI group as compared to the WBRT group (P = 0.003. Conclusions: This study revealed equivalent locoregional and distant disease control in the two groups. APBI offered better overall cosmetic outcome, though at the cost of a slight increase in mild breast fibrosis and telangiectasias.

  9. Space and ground segment performance and lessons learned of the FORMOSAT-3/COSMIC mission: four years in orbit

    Directory of Open Access Journals (Sweden)

    C.-J. Fong

    2011-06-01

    Full Text Available The FORMOSAT-3/COSMIC (Constellation Observing System for Meteorology, Ionosphere, and Climate Mission consisting of six Low-Earth-Orbit (LEO satellites is the world's first demonstration constellation using radio occultation signals from Global Positioning System (GPS satellites. The atmospheric profiles derived by processing radio occultation signals are retrieved in near real-time for global weather/climate monitoring, numerical weather prediction, and space weather research. The mission has processed, on average, 1400 to 1800 high-quality atmospheric sounding profiles per day. The atmospheric radio occultation data are assimilated into operational numerical weather prediction models for global weather prediction, including typhoon/hurricane/cyclone forecasts. The radio occultation data has shown a positive impact on weather predictions at many national weather forecast centers. A follow-on mission was proposed that transitions the current experimental research mission into a significantly improved real-time operational mission, which will reliably provide 8000 radio occultation soundings per day. The follow-on mission, as planned, will consist of 12 LEO satellites (compared to 6 satellites for the current mission with data latency requirement of 45 min (compared to 3 h for the current mission, which will provide greatly enhanced opportunities for operational forecasts and scientific research. This paper will address the FORMOSAT-3/COSMIC system and mission overview, the spacecraft and ground system performance after four years in orbit, the lessons learned from the encountered technical challenges and observations, and the expected design improvements for the spacecraft and ground system for FORMOSAT-7/COSMIC-2.

  10. Port Pirie Cohort Study: environmental exposure to lead and children's abilities at the age of four years

    Energy Technology Data Exchange (ETDEWEB)

    McMichael, A.J.; Baghurst, P.A.; Wigg, N.R.; Vimpani, G.V.; Robertson, E.F.; Roberts, R.J.

    1988-08-25

    We studied the effect of environmental exposure to lead on children's abilities at the age of four years in a cohort of 537 children born during 1979 to 1982 to women living in a community situated near a lead smelter. Samples for measuring blood lead levels were obtained from the mothers antenatally, at delivery from the mothers and umbilical cords, and at the ages of 6, 15, and 24 months and then annually from the children. Concurrently, the mothers were interviewed about personal, family, medical, and environmental factors. Maternal intelligence, the home environment, and the children's mental development (as evaluated with use of the McCarthy Scales of Children's Abilities) were formally assessed. The mean blood lead concentration varied from 0.44 mumol per liter in midpregnancy to a peak of 1.03 mumol per liter at the age of two years. The blood lead concentration at each age, particularly at two and three years, and the integrated postnatal average concentration were inversely related to development at the age of four. Multivariate analysis incorporating many factors in the children's lives indicated that the subjects with an average postnatal blood lead concentration of 1.50 mumol per liter had a general cognitive score 7.2 points lower (95 percent confidence interval, 0.3 to 13.2; mean score, 107.1) than those with an average concentration of 0.50 mumol per liter. Similar deficits occurred in the perceptual-performance and memory scores. Within the range of exposure studied, no threshold dose for an effect of lead was evident. We conclude that postnatal blood lead concentration is inversely related to cognitive development in children, although one must be circumspect in making causal inferences from studies of this relation, because of the difficulties in defining and controlling confounding effects.

  11. Experiences of internet-delivered cognitive behavior therapy for social anxiety disorder four years later: A qualitative study

    Directory of Open Access Journals (Sweden)

    Camilla Olsson Halmetoja

    2014-07-01

    Full Text Available The current study is a qualitative follow-up of a study on guided internet-delivered cognitive behavior therapy (ICBT for social anxiety disorder (SAD, conducted four years after treatment completion. The main aim was to capture participants' description of their experiences of the treatment, their view on treatment effects, memories of the treatment, and whether they continued using the gained knowledge after treatment. Sixty participants were selected from the original study's treatment group. A criterion based sampling approach was used based on the obtained treatment effect, and with a minimum of five completed treatment modules. E-mail invitations were sent, with information about the follow-up and the instruction to respond if interested in participating. Twelve semi-structured interviews were made and the material was analyzed using an approach based on grounded theory. The results showed that all participants found the treatment to have some effect, but they also found it to be demanding, difficult, and hard. Many appreciated to hear of the experiences of other participants in the online forum. Under the theme of memory, most could describe the setup of the treatment in general terms. The exposure module was mentioned by all, cognitive restructuring by most, and some also reported memories of the psychoeducation. A core process was identified which involved how the attained treatment effect was viewed over the time, and how this view changed from treatment completion to current time. The findings outlined in this study describe how treatment effects can be sustained via an active approach to the treatment and the symptoms of SAD.

  12. [Preference Changes Regarding Future Work Area and Intended Position Among German Residents after Four Years of Residency].

    Science.gov (United States)

    Ziegler, Stine; van den Bussche, Hendrik; Römer, Farina; Krause-Solberg, Lea; Scherer, Martin

    2017-06-01

    Introduction We investigated the preferences of medical residents in Germany with regard to future working place (hospital or private practice) and position (employment/self-employment in private practice; resp. specialist/senior or chief physician in the hospital). This is analysed in a gender comparative perspective, including the influence of parenthood. Methods Annual postal surveys among graduates of seven medical faculties in Germany from their last year ("Practical Year") until after four years of postgraduate training. The return rate at baseline was 48 % and the four surveys after reached rates from 85 % up. In all samples about two thirds were women, which corresponds to the actual gender differentiation in under- and postgraduate training. Descriptive statistics and regression analyses were performed. Results Compared to private practice the hospital is clearly preferred, although the attraction of hospital jobs decreased over the years. The decision for or against the hospital is connected to the discipline. Working in private practice is seen as possibility for part time work. Men prefer self-employment whereas women prefer to work under an employment contract. In the hospital, male doctors prefer to work in leading positions. Those positions are associated with full-time work. Leadership training especially takes place in university hospitals. Discussion Three trends are recognized: Reluctance against leading positions, growing interest for part time work and rising popularity of work as an employee in private practice. Those trends can be understood as a rejection of traditional professional role models. The realization of these preferences is easily feasible because of the current labour market situation. Therefore, emerging problems have to be faced in another way. A change of gender-typical role models was rarely detected. © Georg Thieme Verlag KG Stuttgart · New York.

  13. A global survey of aerosol-liquid water cloud overlap based on four years of CALIPSO-CALIOP data

    Science.gov (United States)

    Devasthale, A.; Thomas, M. A.

    2011-02-01

    Simulating the radiative impacts of aerosols located above liquid water clouds presents a significant challenge. In particular, absorbing aerosols, such as smoke, may have significant impact in such situations and even change the sign of net radiative forcing. It is not possible to reliably obtain information on such overlap events from existing passive satellite sensors. However, the CALIOP instrument onboard NASA's CALIPSO satellite allows us to examine these events with unprecedented accuracy. Using four years of collocated CALIPSO 5 km Aerosol and Cloud Layer Version 3 Products (June 2006-May 2010), we quantify, for the first time, the characteristics of overlapping aerosol and water cloud layers globally. We investigate seasonal variability in these characteristics over six latitude bands to understand the hemispheric differences when all aerosol types are included in the analysis (the AAO case). We also investigate frequency of smoke aerosol-cloud overlap (the SAO case). Globally, the frequency is highest during the JJA months in the AAO case, while for the SAO case, it is highest in the SON months. The seasonal mean overlap frequency can regionally exceed 20% in the AAO case and 10% in the SAO case. In about 5-10% cases the vertical distance between aerosol and cloud layers is less than 100 m, while about in 45-60% cases it less than a kilometer in the annual means for different latitudinal bands. In about 70-80% cases, aerosol layers are less than a kilometer thick, while in about 18-22% cases they are 1-2 km thick. The frequency of aerosol layers 2-3 km thick is about 4-5% in the tropical belts during overlap events. Over the regions where high aerosol loadings are present, the overlap frequency can be up to 50% higher when quality criteria on aerosol/cloud feature detection are relaxed. Over the polar regions, more than 50% of the overlapping aerosol layers have optical thickness less than 0.02, but the contribution from the relatively optically thicker

  14. A global survey of aerosol-liquid water cloud overlap based on four years of CALIPSO-CALIOP data

    Directory of Open Access Journals (Sweden)

    A. Devasthale

    2011-02-01

    Full Text Available Simulating the radiative impacts of aerosols located above liquid water clouds presents a significant challenge. In particular, absorbing aerosols, such as smoke, may have significant impact in such situations and even change the sign of net radiative forcing. It is not possible to reliably obtain information on such overlap events from existing passive satellite sensors. However, the CALIOP instrument onboard NASA's CALIPSO satellite allows us to examine these events with unprecedented accuracy. Using four years of collocated CALIPSO 5 km Aerosol and Cloud Layer Version 3 Products (June 2006–May 2010, we quantify, for the first time, the characteristics of overlapping aerosol and water cloud layers globally. We investigate seasonal variability in these characteristics over six latitude bands to understand the hemispheric differences when all aerosol types are included in the analysis (the AAO case. We also investigate frequency of smoke aerosol-cloud overlap (the SAO case. Globally, the frequency is highest during the JJA months in the AAO case, while for the SAO case, it is highest in the SON months. The seasonal mean overlap frequency can regionally exceed 20% in the AAO case and 10% in the SAO case. In about 5–10% cases the vertical distance between aerosol and cloud layers is less than 100 m, while about in 45–60% cases it less than a kilometer in the annual means for different latitudinal bands. In about 70–80% cases, aerosol layers are less than a kilometer thick, while in about 18–22% cases they are 1–2 km thick. The frequency of aerosol layers 2–3 km thick is about 4–5% in the tropical belts during overlap events. Over the regions where high aerosol loadings are present, the overlap frequency can be up to 50% higher when quality criteria on aerosol/cloud feature detection are relaxed. Over the polar regions, more than 50% of the overlapping aerosol layers have optical thickness less than 0.02, but the contribution from

  15. PKS 2005-489 at VHE: four years of monitoring with HESS and simultaneous multi-wavelength observations

    Science.gov (United States)

    H.E.S.S. Collaboration; Acero, F.; Aharonian, F.; Akhperjanian, A. G.; Anton, G.; Barres de Almeida, U.; Bazer-Bachi, A. R.; Becherini, Y.; Behera, B.; Benbow, W.; Bernlöhr, K.; Bochow, A.; Boisson, C.; Bolmont, J.; Borrel, V.; Brucker, J.; Brun, F.; Brun, P.; Bühler, R.; Bulik, T.; Büsching, I.; Boutelier, T.; Chadwick, P. M.; Charbonnier, A.; Chaves, R. C. G.; Cheesebrough, A.; Chounet, L.-M.; Clapson, A. C.; Coignet, G.; Costamante, L.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; O'C. Drury, L.; Dubois, F.; Dubus, G.; Dyks, J.; Dyrda, M.; Egberts, K.; Eger, P.; Espigat, P.; Fallon, L.; Farnier, C.; Fegan, S.; Feinstein, F.; Fiasson, A.; Förster, A.; Fontaine, G.; Füßling, M.; Gabici, S.; Gallant, Y. A.; Gérard, L.; Gerbig, D.; Giebels, B.; Glicenstein, J. F.; Glück, B.; Goret, P.; Göring, D.; Hauser, M.; Heinz, S.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hinton, J. A.; Hoffmann, A.; Hofmann, W.; Hofverberg, P.; Holleran, M.; Hoppe, S.; Horns, D.; Jacholkowska, A.; de Jager, O. C.; Jahn, C.; Jung, I.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Kerschhaggl, M.; Khangulyan, D.; Khélifi, B.; Keogh, D.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Komin, Nu.; Kosack, K.; Kossakowski, R.; Lamanna, G.; Lenain, J.-P.; Lohse, T.; Marandon, V.; Martineau-Huynh, O.; Marcowith, A.; Masbou, J.; Maurin, D.; McComb, T. J. L.; Medina, M. C.; Méhault, J.; Moderski, R.; Moulin, E.; Naumann-Godo, M.; de Naurois, M.; Nedbal, D.; Nekrassov, D.; Nicholas, B.; Niemiec, J.; Nolan, S. J.; Ohm, S.; Olive, J.-F.; de Oña Wilhelmi, E.; Orford, K. J.; Ostrowski, M.; Panter, M.; Paz Arribas, M.; Pedaletti, G.; Pelletier, G.; Petrucci, P.-O.; Pita, S.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raubenheimer, B. C.; Raue, M.; Rayner, S. M.; Renaud, M.; Rieger, F.; Ripken, J.; Rob, L.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Ruppel, J.; Sahakian, V.; Santangelo, A.; Schlickeiser, R.; Schöck, F. M.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Shalchi, A.; Sikora, M.; Skilton, J. L.; Sol, H.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Superina, G.; Szostek, A.; Tam, P. H.; Tavernet, J.-P.; Terrier, R.; Tibolla, O.; Tluczykont, M.; van Eldik, C.; Vasileiadis, G.; Venter, C.; Venter, L.; Vialle, J. P.; Vincent, P.; Vivier, M.; Völk, H. J.; Volpe, F.; Wagner, S. J.; Ward, M.; Zdziarski, A. A.; Zech, A.

    2010-02-01

    Aims: Our aim is to study the very high energy (VHE; E>100 GeV) γ-ray emission from BL Lac objects and the evolution in time of their broad-band spectral energy distribution (SED). Methods: VHE observations of the high-frequency peaked BL Lac object PKS 2005-489 were made with the High Energy Stereoscopic System (HESS) from 2004 through 2007. Three simultaneous multi-wavelength campaigns at lower energies were performed during the HESS data taking, consisting of several individual pointings with the XMM-Newton and RXTE satellites. Results: A strong VHE signal, ~17σ total, from PKS 2005-489 was detected during the four years of HESS observations (90.3 h live time). The integral flux above the average analysis threshold of 400 GeV is ~3% of the flux observed from the Crab Nebula and varies weakly on time scales from days to years. The average VHE spectrum measured from ~300 GeV to ~5 TeV is characterized by a power law with a photon index, Γ = 3.20± 0.16_stat± 0.10_syst. At X-ray energies the flux is observed to vary by more than an order of magnitude between 2004 and 2005. Strong changes in the X-ray spectrum (ΔΓX ≈ 0.7) are also observed, which appear to be mirrored in the VHE band. Conclusions: The SED of PKS 2005-489, constructed for the first time with contemporaneous data on both humps, shows significant evolution. The large flux variations in the X-ray band, coupled with weak or no variations in the VHE band and a similar spectral behavior, suggest the emergence of a new, separate, harder emission component in September 2005. Supported by CAPES Foundation, Ministry of Education of Brazil.Now at Harvard-Smithsonian Center for Astrophysics, Cambridge, USA.Now at W.W. Hansen Experimental Physics Laboratory & Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, USA.

  16. Spatiotemporal Determinants of Urban Leptospirosis Transmission: Four-Year Prospective Cohort Study of Slum Residents in Brazil.

    Directory of Open Access Journals (Sweden)

    José E Hagan

    2016-01-01

    Full Text Available Rat-borne leptospirosis is an emerging zoonotic disease in urban slum settlements for which there are no adequate control measures. The challenge in elucidating risk factors and informing approaches for prevention is the complex and heterogeneous environment within slums, which vary at fine spatial scales and influence transmission of the bacterial agent.We performed a prospective study of 2,003 slum residents in the city of Salvador, Brazil during a four-year period (2003-2007 and used a spatiotemporal modelling approach to delineate the dynamics of leptospiral transmission. Household interviews and Geographical Information System surveys were performed annually to evaluate risk exposures and environmental transmission sources. We completed annual serosurveys to ascertain leptospiral infection based on serological evidence. Among the 1,730 (86% individuals who completed at least one year of follow-up, the infection rate was 35.4 (95% CI, 30.7-40.6 per 1,000 annual follow-up events. Male gender, illiteracy, and age were independently associated with infection risk. Environmental risk factors included rat infestation (OR 1.46, 95% CI, 1.00-2.16, contact with mud (OR 1.57, 95% CI 1.17-2.17 and lower household elevation (OR 0.92 per 10m increase in elevation, 95% CI 0.82-1.04. The spatial distribution of infection risk was highly heterogeneous and varied across small scales. Fixed effects in the spatiotemporal model accounted for the majority of the spatial variation in risk, but there was a significant residual component that was best explained by the spatial random effect. Although infection risk varied between years, the spatial distribution of risk associated with fixed and random effects did not vary temporally. Specific "hot-spots" consistently had higher transmission risk during study years.The risk for leptospiral infection in urban slums is determined in large part by structural features, both social and environmental. Our findings

  17. GeoFORCE Alaska: Four-Year Field Program Brings Rural Alaskan High School Students into the STEM Pipeline

    Science.gov (United States)

    Fowell, S. J.; Rittgers, A.; Stephens, L.; Hutchinson, S.; Peters, H.; Snow, E.; Wartes, D.

    2016-12-01

    GeoFORCE Alaska is a four-year, field-based, summer geoscience program designed to raise graduation rates in rural Alaskan high schools, encourage participants to pursue college degrees, and increase the diversity of Alaska's technical workforce. Residents of predominantly Alaska Native villages holding degrees in science, technology, engineering, or math (STEM) bring valuable perspectives to decisions regarding management of cultural and natural resources. However, between 2010 and 2015 the average dropout rate for students in grades 7-12 was 8.5% per year in the North Slope School District and 7% per year in the Northwest Arctic School District. 2015 graduation rates were 70% and 75%, respectively. Statewide statistics highlight the challenge for Alaska Native students. During the 2014-2015 school year alone 37.6% of Alaska Native students dropped out of Alaskan public schools. At the college level, Alaska Native students are underrepresented in University of Alaska Fairbanks (UAF) science departments. Launched in 2012 by UAF in partnership with the longstanding University of Texas at Austin program, GeoFORCE applies the cohort model, leading the same group of high school students on geological field academies during four consecutive summers. Through a combination of active learning, teamwork, and hands-on projects at spectacular geological locations, students gain academic skills and confidence that facilitate high school and college success. To date, GeoFORCE Alaska has recruited two cohorts. 78% of these students identify as Alaska Native, reflecting community demographics. The inaugural cohort of 18 students from the North Slope Borough completed the Fourth-Year Academy in summer 2015. 94% of these students graduated from high school, at least 72% plan to attend college, and 33% will major in geoscience. A second cohort of 34 rising 9th and 10th graders entered the program in 2016. At the request of corporate sponsors, this cohort was recruited from both the

  18. A global survey of aerosol-liquid water cloud overlap based on four years of CALIPSO-CALIOP data

    Directory of Open Access Journals (Sweden)

    A. Devasthale

    2010-09-01

    Full Text Available The presence of aerosols over highly reflective liquid water cloud tops poses a big challenge in simulating their radiative impacts. Particularly, absorbing aerosols, such as smoke, may have significant impact in such situations and even change the sign of net radiative forcing. Until now, it was not possible to obtain information on such overlap events realistically from the existing passive satellite sensors. However, the CALIOP instrument onboard NASA's CALIPSO satellite allows us to examine these events with an unprecedented accuracy.

    Using four years of collocated CALIPSO 5 km Aerosol and Cloud Layer Version 3 Products (June 2006–May 2010, we quantify, for the first time, the macrophysical characteristics of overlapping aerosol and water cloud layers globally. We investigate seasonal variability in these characteristics over six latitude bands to understand the hemispheric differences. We compute a the percentage cases when such overlap is seen globally and seasonally when all aerosol types are included (AAO case in the analysis, b the joint histograms of aerosol layer base height and cloud layer top height, and c the joint histograms of aerosol and cloud geometrical thicknesses in such overlap cases. We also investigate frequency of smoke aerosol-cloud overlap (SAO case.

    The results show a distinct seasonality in overlap frequency in both AAO and SAO cases. Globally, the frequency is highest during JJA months in AAO case, while for the SAO case, it is highest in SON months. The seasonal mean overlap frequency can regionally exceed 20% in AAO case and 10% in SAO case. There is a tendency that the vertical separation between aerosol and cloud layers increases from high to low latitude regions in the both hemispheres. In about 5–10% cases the vertical distance between aerosol and cloud layers is less than 100 m, while about in 45–60% cases it less than a kilometer in the annual means for different latitudinal bands

  19. Specific immunotherapy in atopic dermatitis--Four-year treatment in different age and airborne allergy type subgroups.

    Science.gov (United States)

    Czarnecka-Operacz, Magdalena; Silny, Wojciech

    2006-01-01

    Atopic dermatitis (AD) is a common inflammatory disease involving the skin and frequently other organs and systems such as respiratory system. The recently recognized atopic nature of the skin inflammation in AD has raised a growing interest in the treatment with allergen-specific immunotherapy (SIT). In this study, the efficacy of SIT was evaluated in a group of 37 AD patients aged 5-44 years: 14 allergic to house dust mites (HDM), 17 to grass pollen allergens, and 6 allergic to grass and mugwort pollen allergens. IgE-mediated airborne allergy was well documented in all cases. SIT was performed with Novo Helisen Depot allergy vaccines of appropriate composition. Control group included 29 patients with AD and confirmed IgE-mediated airborne allergy to analogous allergens: HDM, 14 patients; grass pollen allergens, 11 patients; and grass and mugwort pollen allergens, 4 patients. Conventional methods of AD treatment were used in the control group. Clinical evaluation of patients was performed with W-AZS index after 12, 24, 36 and 48 months of therapy. SIT was found to be an efficacious and safe method of treatment for selected patients with AD and IgE-mediated airborne allergy. The efficacy of this therapeutic method was significantly higher than that recorded by conventional methods used in the control group in all 3 age subgroups and all 3 types of airborne allergy (HDM, grass pollen, and grass and mugwort pollen). It is concluded that SIT may be highly promising method of controlling skin inflammation in AD with the potential to prevent the development of AD into respiratory allergy.

  20. Changes in particulate matter physical properties during Saharan advections over Rome (Italy: a four-year study, 2001–2004

    Directory of Open Access Journals (Sweden)

    R. Sozzi

    2013-02-01

    Full Text Available Particulate matter mass concentrations measured in the city of Rome (Italy in the period 2001–2004 have been cross-analysed with concurrent Saharan dust advection events to infer the impact these natural episodes bear on the standard air quality parameter PM10 observed at two city stations and at one regional background station. Natural events as Saharan dust advections are associated to a definite health risk. At the same time, the Directive 2008/50/EC allows subtraction of PM exceedances caused by natural contributions from statistics used to determine air-quality of EU sites. In this respect, it is important to detect and characterize such advections by means of reliable, operational techniques. To assess the PM10 increase we used both the "regional-background method" suggested by EC Guidelines and a "local background" one, demonstrated to be most suited to this central Mediterranean region. The two approaches provided results within 20% from each other. The sequence of Saharan advections over the city has been either detected by Polarization Lidar (laser radar observations or forecast by the operational numerical regional mineral dust model BSC-DREAM8b of the Barcelona Supercomputing Centre. Lidar observations were also employed to retrieve the average physical properties of the dust clouds as a function of height. Along the four-year period, Lidar measurements (703 evenly distributed days revealed Saharan plumes transits over Rome on 28.6% of the days, with minimum occurrence in wintertime. Dust was observed to reach the ground on 17.5% of the days totalling 88 episodes. Most (90% of these advections lasted up to 5 days, averaging to ~3 days. Median time lag between advections was 7 days. Typical altitude range of the dust plumes was 0–6 km, with centre of mass at ~3 km a.g.l. BSC-DREAM8b model simulations (1461 days predicted Lidar detectable (532nm extinction coefficient >0.005 km−1 dust advections on 25.9% of the days, with ground

  1. Four-year measurement of methane flux over a temperate forest with a relaxed eddy accumulation method

    Science.gov (United States)

    Sakabe, A.; Kosugi, Y.; Ueyama, M.; Hamotani, K.; Takahashi, K.; Iwata, H.; Itoh, M.

    2013-12-01

    Forests are generally assumed to be an atmospheric methane (CH4) sink (Le Mer and Roger, 2001). However, under Asian monsoon climate, forests are subject to wide spatiotemporal range in soil water status, where forest soils often became water-saturated condition heterogeneously. In such warm and humid conditions, forests may act as a CH4 source and/or sink with considerable spatiotemporal variations. Micrometeorological methods such as eddy covariance (EC) method continuously measure spatially-representative flux at a canopy scale without artificial disturbance. In this study, we measured CH4 fluxes over a temperate forest during four-year period using a CH4 analyzer based on tunable diode laser spectroscopy detection with a relaxed eddy accumulation (REA) method (Hamotani et al., 1996, 2001). We revealed the amplitude and seasonal variations of canopy-scale CH4 fluxes. The REA method is the attractive alternative to the EC method to measure trace-gas flux because it allows the use of analyzers with an optimal integration time. We also conducted continuous chamber measurements on forest floor to reveal spatial variations in soil CH4 fluxes and its controlling processes. The observations were made in an evergreen coniferous forest in central Japan. The site has a warm temperate monsoon climate with wet summer. Some wetlands were located in riparian zones along streams within the flux footprint area. For the REA method, the sonic anemometer (SAT-550, Kaijo) was mounted on top of the 29-m-tall tower and air was sampled from just below the sonic anemometer to reservoirs according to the direction of vertical wind velocity (w). After accumulating air for 30 minutes, the air in the reservoirs was pulled into a CO2/H2O gas analyzer (LI-840, Li-Cor) and a CH4 analyzer (FMA-200, Los Gatos Research). Before entering the analyzers, the sampled air was dried using a gas dryer (PD-50 T-48; Perma Pure Inc.). The REA flux is obtained from the difference in the mean concentrations

  2. Potholes on the Road to College: High School Effects in Shaping Urban Students' Participation in College Application, Four-Year College Enrollment, and College Match

    Science.gov (United States)

    Roderick, Melissa; Coca, Vanessa; Nagaoka, Jenny

    2011-01-01

    This article examines the extent to which indicators of the college-going climate of urban high schools are associated with students' application to, enrollment in, and choice among four-year colleges. The investigators examine two mechanisms by which high schools may shape college enrollment among low-income students in an urban school system:…

  3. Predicting School Problems from Preschool Developmental Screening: A Four-Year Follow-Up of the Revised Denver Developmental Screening Test and the Role of Parent Report.

    Science.gov (United States)

    Diamond, Karen E.

    1987-01-01

    The Revised Denver Developmental Screening Test and parental reports of developmental concerns were compared for effectiveness in predicting school problems four years after a preschool screening program. Results suggested the test accurately identified only those children later found to have severe learning problems. (Author/DB)

  4. Women in Leadership: Factors That Affect the Achievement of Women in Higher Education Administration at Four-Year Public and Private Universities in Texas

    Science.gov (United States)

    Ramirez, Dawn Marie

    2012-01-01

    The purpose of this quantitative study was to examine the factors that affect women administrators in higher education at four-year public and private universities in Texas. By comparing private and public universities, the research provided an assessment of similarities and differences of the factors impacting achievement of women in higher…

  5. Examining Factors of Acculturative Stress on International Students as They Affect Utilization of Campus-Based Health and Counseling Services at Four-Year Public Universities in Ohio

    Science.gov (United States)

    Hofmann, Paul N.

    2010-01-01

    This study examined factors of acculturative stress experienced by international students as they affect utilization of campus-based health and counseling services. Eight hundred thirty-eight international students studying at 11 four-year public institutions in the State of Ohio were surveyed to determine how frequently they had experienced 20…

  6. Examining Factors of Acculturative Stress on International Students as They Affect Utilization of Campus-Based Health and Counseling Services at Four-Year Public Universities in Ohio

    Science.gov (United States)

    Hofmann, Paul N.

    2010-01-01

    This study examined factors of acculturative stress experienced by international students as they affect utilization of campus-based health and counseling services. Eight hundred thirty-eight international students studying at 11 four-year public institutions in the State of Ohio were surveyed to determine how frequently they had experienced 20…

  7. Prognosis and Continuity of Child Mental Health Problems from Preschool to Primary School: Results of a Four-Year Longitudinal Study

    Science.gov (United States)

    Beyer, Thomas; Postert, Christian; Muller, Jorg M.; Furniss, Tilman

    2012-01-01

    In a four-year longitudinal study, changes in and continuity of behavioral and emotional problems were examined in 814 subjects from kindergarten to primary school. Mental health problems were assessed by means of the Child Behavior Checklist (CBCL). The distribution of the CBCL broadband groups revealed a high level of continuity of internalizing…

  8. Transforming the Terminal Associates of Applied Science into a Four-Year Degree: A Win-Win Situation for Students, Community Colleges, Universities, and Businesses

    Science.gov (United States)

    Batts, David L.; Pagliari, Leslie R.

    2013-01-01

    Associates of Applied Science (AAS) degrees were once considered terminal degrees and were developed for people seeking technical skills to join the workforce. This paper discusses the transformation from a transferable degree into technical four-year baccalaureate degree. It also discusses survey results of students currently in a degree…

  9. Community College Transfer Students' Probabilities of Baccalaureate Receipt as a Function of Their Prevalence in Four-Year Colleges and Departments

    Science.gov (United States)

    Nutting, Andrew W.

    2011-01-01

    The present paper determines whether community college transfer students have higher baccalaureate rates when they enroll in four-year colleges and departments that have larger shares of transfer students. Transfers attending non-technical campuses with larger shares of transfers have higher eight-year baccalaureate rates, but within-campus…

  10. An Exploratory Study on the Purpose, Structure, Format and Use of Syllabi at a Midwest Four-Year Undergraduate Private University

    Science.gov (United States)

    Fink, Susan Jo Breakenridge

    2011-01-01

    The purpose of this study was to explore how instructors at a mid-sized Midwest four-year undergraduate private university view the purpose, structure, format and use of their course syllabi. The theory of structural functionalism and a quantitative research approach were employed. A group administration approach was used to distribute the paper…

  11. A Comparison of Academic Administrators and Enrollment Managers' Perceptions of Undergraduate Enrollment Management Functions at a Subset of Four-Year Public Institutions

    Science.gov (United States)

    Cesarini, Lisa McHugh

    2011-01-01

    The purpose of this study was to examine perceptions of various enrollment management functions at a subset of four-year public institutions. Specifically, this study compared perceptions of academic administrators with enrollment managers as they related to the availability, need, and effectiveness of certain enrollment management functions. In…

  12. A Comparison of Academic Administrators and Enrollment Managers' Perceptions of Undergraduate Enrollment Management Functions at a Subset of Four-Year Public Institutions

    Science.gov (United States)

    Cesarini, Lisa McHugh

    2011-01-01

    The purpose of this study was to examine perceptions of various enrollment management functions at a subset of four-year public institutions. Specifically, this study compared perceptions of academic administrators with enrollment managers as they related to the availability, need, and effectiveness of certain enrollment management functions. In…

  13. Robotic-assisted pyeloplasty:recent developments in efficacy, outcomes, and new techniques.

    Science.gov (United States)

    Seideman, Casey A; Bagrodia, Aditya; Gahan, Jeffrey; Cadeddu, Jeffrey A

    2013-02-01

    Within the last decade, the adaptation of robotic urologic surgery has had a profound impact on surgical practice, with robotic upper tract reconstruction for ureteropelvic junction obstruction gaining rapid acceptance. Recent advances in robotic reconstruction demonstrate efficacious outcomes of robotic pyeloplasty, as compared with conventional laparoscopic pyeloplasty, even in the case of secondary surgery. Furthermore, efforts to continue to reduce the morbidity of laparoscopic surgery have led to the development and implementation of laparoendoscopic single-site (LESS) surgery. The recent applications of the da Vinci robotic surgical platform to LESS pyeloplasty (R-LESS) has demonstrated the potential to further decrease morbidity, improve surgeon ergonomics, and improve cosmesis.

  14. The effect of nurse education on the self-esteem and assertiveness of nursing students: A four-year longitudinal study.

    Science.gov (United States)

    İlhan, Nesrin; Sukut, Özge; Akhan, Latife Utaş; Batmaz, Makbule

    2016-04-01

    The nurse education program affects many aspects of personal development. Nursing students gain skills in critical thinking and analysis and also develop communication and management skills. The four-year program may also have an effect on students' assertiveness and self-esteem. This study was conducted to determine the impact of the four-year higher nursing school educational program on students' self-esteem and assertiveness. Descriptive longitudinal design. The study took place at a Foundation University in Istanbul, Turkey over the period 2006-2010. The students' levels of self-esteem and assertiveness were assessed at the beginning and end of the first, second, third and fourth years of the program. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. An Analysis on Thailand's Economic Situation During Thaksin'Four- year Administration%他信执政四年来泰国经济形势分析

    Institute of Scientific and Technical Information of China (English)

    谢丽梅

    2005-01-01

    Since Thaksin' s four - year rule, Thailand' s economy has been steered out of the shadow of financial crisis, moved into a new turn of accelerating growth and is now walking towards the continuous and steady track thanks to ,from the internal factor, his Administration' s dual - track economic policy and from the external factor, the recovery of the international economic situation and the accelerating growth of Chinese economy.

  16. The Socio-Cultural and Leadership Experiences of Latina Four-Year College and University Presidents: A Traves de sus Voces (Through Their Voices)

    Science.gov (United States)

    Maes, Johanna B.

    2012-01-01

    The Latina population in the United States is one of the largest of all racial and ethnic groups, and it is expected to grow exponentially within the next forty years. Despite these large numbers of Latinas in the U.S., there is a disparity with this population who are leading our nation's four-year colleges and universities. A reason for…

  17. A four-year follow-up controlled study of stress response and symptom persistence in Brazilian children and adolescents with attention deficit disorder and hyperactivity (ADHD).

    Science.gov (United States)

    Palma, Sonia Maria Motta; Natale, Ana Carolina Motta Palma; Calil, Helena Maria

    2015-12-15

    This study evaluated children and adolescents with Attention Deficit Disorder andHyperactivity Disorder (ADHD), reassessing them at a four-year follow-up. Their cortisol response to a stress stimulus was measured twice. ADHD symptom persistence, development of comorbidities, and psychostimulant usage were also reassessed. The initial sample consisted of 38 ADHD patients and 38 healthy controls, age ranging 6-14. At the follow-up, there were 37 ADHD patients and 22 healthy controls, age ranging 10-18. ADHD was classified as persistent if the patients fulfilled all DSM IV criteria for syndromic or subthreshold or had functional impairment. Salivary cortisol samples were collected prior to the application of a cognitive stressor (Continuous Performance Test - CPT), and at three time intervals afterwards at baseline and at the follow-up. Their reassessment showed that 75% had persistent symptoms, psychiatric comorbidities (oppositional defiant and behavioral disorders), functional and academic impairement. Only seven patients were on medication. The ADHD group's cortisol levels were lower than those measured four years earlier, but cortisol concentrations were similar for both ADHD and control groups at the four-year follow-up. The cortisol results suggest that HPA axis reactivity could be a marker differentiating ADHD from ADHD with comorbidities.

  18. Bullying and victimisation are common in four-year-old children and are associated with somatic symptoms and conduct and peer problems.

    Science.gov (United States)

    Ilola, Anna-Marja; Lempinen, Lotta; Huttunen, Jukka; Ristkari, Terja; Sourander, Andre

    2016-05-01

    There are few population-based studies on bullying behaviour among preschool children. The aims of the study were to investigate the prevalence of bullying behaviour among four-year-old children, as reported by their parents, the prevalence of types of bullying behaviour and the associations between bullying behaviour and psychosocial factors. This study was based on a population-based study sample of 931 children who attended their check-up at a child health clinic at four years of age. Parents completed the questionnaire about their child's bullying behaviour and risk factors during the check-up. Bullying behaviour, especially being both a bully and a victim, was a common phenomenon among four-year-old children. Being a bully or both a bully and victim were most strongly associated with conduct problems, while being a victim was associated with somatic symptoms and peer problems. Bullying behaviour was frequently found in preschool children and associated with a wide range of other problems, which indicate that routine checking of bullying behaviour should be included in child health clinic check-ups. Bullying prevention programmes are usually targeted at school-aged children, but this study highlights the importance of focusing already on preschool children. ©2016 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  19. Forty Four Years a King.

    Science.gov (United States)

    Minneapolis Public Schools, Minn. Dept. of Intergroup Education.

    This curriculum unit contains guidelines for Martin Luther King Jr. Day, January 15th. Items included in the guide are: a list of suggested activities, a short biography of Dr. King, excerpts from some of his speeches including the famous, "I Have A Dream" speech, a play, study questions, "A King's Journey", a game, and a story…

  20. Post-traumatic stress disorder and its predictors among bereaved Tibetan adolescents four years after the Yushu earthquake: a cross-sectional survey in China.

    Science.gov (United States)

    Dongling, Liu; Hui, Chen; Ling, Ma; Wenqian, Bie; Zailiang, Liu; Changying, Chen

    2017-04-01

    To examine the prevalence of post-traumatic stress disorder symptoms and to explore the predictive factors of post-traumatic stress disorder symptoms among bereaved adolescents four years after the Yushu earthquake. On 14 April 2010, the 7·1-magnitude Yushu earthquake occurred in the high-altitude, hypoxia-prone regions primarily inhabited by ethnic minorities. Many adolescents lost their parents during the earthquake. This study examined post-traumatic stress disorder and its predictors among bereaved Tibetan adolescents four years after the trauma in China. This was a cross-sectional descriptive study. This study used a cross-sectional design with 830 bereaved adolescents. Participant demographic data included gender, age and grade, and the earthquake exposure variables included the deceased relatives, whether they were buried, injured or amputated (non-life-threatening) and whether they witnessed a burial, injury or death. The post-traumatic stress disorder Checklist-Civilian version was used to assess the symptoms and prevalence of post-traumatic stress disorder, and the Coping Style Scale assessed coping styles. The results indicated that the prevalence of post-traumatic stress disorder was 19·3%. Individuals who were buried, injured or amputated (non-life-threatening), who witnessed a burial, injury or death, who suffered severe property loss during the earthquake and who had negative coping skills were the most likely individuals to have post-traumatic stress disorder symptoms. The presence of post-traumatic stress disorder was very prevalent among adolescents four years after the Yushu earthquake. Effective mental health services should be developed to facilitate postdisaster recovery for bereaved adolescents at high risk for post-traumatic stress disorder. The findings in this study improve our understanding of post-traumatic stress disorder and related risk factors in bereaved adolescents in non-Western communities, providing useful information for

  1. Auditory-visual speech perception in three- and four-year-olds and its relationship to perceptual attunement and receptive vocabulary.

    Science.gov (United States)

    Erdener, Doğu; Burnham, Denis

    2017-06-06

    Despite the body of research on auditory-visual speech perception in infants and schoolchildren, development in the early childhood period remains relatively uncharted. In this study, English-speaking children between three and four years of age were investigated for: (i) the development of visual speech perception - lip-reading and visual influence in auditory-visual integration; (ii) the development of auditory speech perception and native language perceptual attunement; and (iii) the relationship between these and a language skill relevant at this age, receptive vocabulary. Visual speech perception skills improved even over this relatively short time period. However, regression analyses revealed that vocabulary was predicted by auditory-only speech perception, and native language attunement, but not by visual speech perception ability. The results suggest that, in contrast to infants and schoolchildren, in three- to four-year-olds the relationship between speech perception and language ability is based on auditory and not visual or auditory-visual speech perception ability. Adding these results to existing findings allows elaboration of a more complete account of the developmental course of auditory-visual speech perception.

  2. Triclocarban, triclosan and its transformation product methyl triclosan in native earthworm species four years after a commercial-scale biosolids application.

    Science.gov (United States)

    Macherius, André; Lapen, David R; Reemtsma, Thorsten; Römbke, Jörg; Topp, Edward; Coors, Anja

    2014-02-15

    Triclocarban (TCC), triclosan (TCS) and methyl triclosan (Me-TCS) were detected in soil and the native population of earthworms of an agricultural field in Ottawa, Canada, about four years after a commercial-scale application of biosolids. In soil that received biosolids, TCC and TCS were detected at median concentrations of 13.0 and 1.5 ng/g soil (d.w.), respectively, while Me-TCS, the transformation product of triclosan, was detected at a six-fold higher median concentration than its precursor. In earthworms collected at the biosolids-amended field-plot about four years post application, Me-TCS was also detected at higher concentrations (26 to 114 ng/g tissue d.w.) than TCS (16-51 ng/g) and TCC (4-53 ng/g). These data provide evidence that not only parent compounds but also their transformation products need to be considered in faunal bioaccumulation studies. Moreover, the preliminary results for pooled earthworm samples from different ecological groups suggest that the degree of bioaccumulation of biosolids-associated contaminants may depend on the habitat and feeding behavior of the organisms.

  3. [REPORTING CRITICAL LAB RESULTS, A CHALLENGE FOR THE LAB AND THE PHYSICIAN - A SUMMARY OF FOUR YEARS OF EXPERIENCE IN MEIR MEDICAL CENTER LABORATORIES].

    Science.gov (United States)

    Rashid, Gloria; Goldman, Jacob; Weinstein, Doron; Tohami, Tali; Neumark, Eran; Weiss, Eli

    2015-08-01

    Critical laboratory results require prompt reporting to the attending physician, as they may indicate that a patient is in a life-threatening condition. Although this important subject has been covered in many publications, it needs more attention from our healthcare organizations, which have no official policy on the subject. Matching expectations between the doctor and the laboratory needs to be better defined. The aim of this work was to inform the community of doctors and laboratories about the multiple problems concerning the reporting of critical laboratory results, to create a platform for exchanging views and ideas, and to build an extensive infrastructure for developing a unified plan to address this important issue. We present the results of four years of experience of reporting critical laboratory values at the Meir Medical Center Laboratories. The idea leading this work was to present the relatively low rate of critical results reported by the laboratories in 2010, sharing the problems discovered while investigating the situation in depth, and presenting the solutions that enabled us to obtain the desired results within four years. Gradual implementation of these improvements resulted in critical value reporting increasing from 55% in 2010 to 95% currently. We suggest a model for improving critical laboratory values reporting based on our 4-year experience, which emphasizes: (1) The importance of selecting proper tests and values for critical results; (2) The significance of using technology and computerized measures to support the process; and (3) Developing quick procedures for monitoring and controlling the process.

  4. Lifestyle and Dietary Factors Associated with the Evolution of Cardiometabolic Risk over Four Years in West-African Adults: The Benin Study

    Directory of Open Access Journals (Sweden)

    Charles Sossa

    2013-01-01

    Full Text Available Aim. To assess in adults from Benin changes in cardiometabolic risk (CMR using both the Framingham risk score (FRS and metabolic syndrome (MetS and to examine the effects of diet, and lifestyles, controlling for location and socioeconomic status. Methods. Apparently healthy subjects (n=541 aged 25–60 years and randomly selected in the largest city, a small town, and rural areas were included in the four-year longitudinal study. Along with CMR factors, socioeconomic, diet and lifestyle data were collected in individual interviews. A food score based on consumption frequency of four “sentinel” food groups (meat and poultry, dairy, eggs, and vegetables was developed. Lifestyle included physical activity, alcohol and tobacco use. Education and income (proxy were the socioeconomic variables. Results. Among the subjects with four-year follow-up data (n=416, 13.5% were at risk at baseline, showing MetS or FRS ≥ 10%. The incidence of MetS and FRS ≥ 10% during follow-up was 8.2% and 5%, respectively. CMR deteriorated in 21% of subjects. Diet and lifestyle mediated location and income effects on CMR evolution. Low food scores and inactivity increased the likelihood of CMR deterioration. Conclusion. Combining MetS and FRS might be appropriate for surveillance purposes in order to better capture CMR and inform preventive measures.

  5. Long Term Effect on Professionals' Knowledge, Practice and Attitudes towards User Involvement Four Years after Implementing an Organisational Development Plan: A Controlled Study.

    Directory of Open Access Journals (Sweden)

    Marit By Rise

    Full Text Available Health service organisations are increasingly implementing user involvement initiatives according to requirements from governments, such as user representation in administrational boards, better information to users, and more involvement of the users during treatment. Professionals are vital in all initiatives to enhance user involvement, and initiatives to increase involvement should influence the professionals' practice and attitudes. The implementation of a development plan intending to enhance user involvement in a mental health hospital in Central Norway had no effect on the professionals after 16 months. The objective was therefore to investigate the long term effect on the professionals' knowledge, practice and attitudes towards user involvement after four years.This was a non-randomized controlled study including professionals from three mental health hospitals in Central Norway. A development plan intended to enhance user participation was implemented in one of the hospitals, including establishing a patient education centre and a user office, purchasing of user expertise, appointing contact professionals for next of kin, and improving of the centre's information and the professional culture. The professionals at two other hospitals constituted the control group. All professionals were invited to answer the Consumer Participation Questionnaire (CPQ and additional questions, at a four year interval.A total of 399 professionals participated (43% response rate. Comparing the changes in the intervention group with the changes in the control group, the results showed that the plan had improved some aspects of the professionals' knowledge about the user involvement taking place in the hospital. In addition, some parts of the professionals' practice of providing information to the service users was improved, and the development plan might have raised their awareness about insufficient involvement of next of kin.This is the first controlled

  6. Physical Activity and Fruit and Vegetable Intake among Black and White Female College Students at Two- and Four-Year Colleges and Universities

    Science.gov (United States)

    Goodwin, Sherell Brown; Stratton, Erin; Lowe, Kincaid; Grimsley, Linda; Rodd, Jan; Williams, Catherine; Mattox, Cheri; Foster, Bruce

    2014-01-01

    Objective We compared fruit and vegetable (FV) intake, physical activity (PA), and overweight/ obesity among Black and White females attending two- and four-year colleges. Methods We recruited 24,055 students at six colleges in the Southeast to complete an online survey, yielding 4840 responses (20.1% response rate). The current analyses focused on the 2276 Black and White females. Results Binary logistic regression analyses indicated that recommended FV intake among White females was associated with greater extraversion (Odds Ratio [OR] = 1.05, 95% Confidence Interval [CI] 1.00, 1.11, p = 0.05) and greater conscientiousness (OR = 1.08, CI 1.02, 1.14, p = 0.01), whereas among Black females correlates included greater openness to experience (OR = 1.08, CI 1.01, 1.15, p = 0.03). Ordinal logistic regression analyses indicated that, among White females, greater PA was associated with attending a four-year college (Beta = 0.27, CI 0.01, 0.53, p = 0.04), whereas among Black females, correlates were with younger age (Beta = 0.01, CI 0.17, 0.03, p = 0.003) and greater emotional stability (Beta = 0.07, CI 0.01, 0.13, p = 0.02). Binary logistic regression analyses indicated that, among White females, being overweight or obese was associated with older age (OR = 1.08, CI 1.01, 1.16, p = 0.03), attending a two-year college (OR = 1.62, CI 1.22, 2.16, p = 0.001), and lower satisfaction with life (OR = 0.96, CI 0.94, 0.98, p = 0.002), whereas among Black females, being overweight or obese was associated with older age (OR = 1.87, CI 1.10, 1.28, p < 0.001). Conclusions Identifying factors related to obesity-related factors is critical in developing interventions targeting factors associated with overweight and obesity among Black and White females attending two- and four-year colleges. Moreover, understanding different college settings and the contextual factors associated with overweight/obesity is critical. PMID:25328836

  7. Central odontogenic fibroma (simple type) in a four year old boy: Atypical cone-beam computed tomographic appearance with periosteal reaction

    Energy Technology Data Exchange (ETDEWEB)

    Anbiaee, Najme; Ebrahimnejad, Hamed; Sanaei, Alireza [Dept. of , Oral and Maxillofacial Radiology, Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of)

    2015-06-15

    Central odontogenic fibroma (COF) is a rare benign tumor that accounts for 0.1% of all odontogenic tumors. A case of COF (simple type) of the mandible in a four-year-old boy is described in this report. The patient showed asymptomatic swelling in the right inferior border of the lower jaw for one week. A panoramic radiograph showed a poorly-defined destructive unilocular radiolucent area. Cone-beam computed tomography showed expansion and perforation of the adjacent cortical bone plates. A periosteal reaction with the Codman triangle pattern was clearly visible in the buccal cortex. Since the tumor had destroyed a considerable amount of bone, surgical resection was performed. No recurrence was noted.

  8. Compliance in the First Four Years of AAS 27 Financial Reporting by Local Government: A Study of the New South Wales Experience

    Directory of Open Access Journals (Sweden)

    Gregory Kenneth Laing

    2007-06-01

    Full Text Available This paper reports on a longitudinal study of the levels of compliance for the first fouryears (1994 to1997 following the introduction of the Australian Accounting Standard(AAS 27. The annual reports of all 177 local government councils in NSW wereanalysed revealing a high level of compliance with the standard. The main cause fornon-compliance was the complexity of the recognition and treatment of assets. Inaddition a number of problems were identified, in particular the timeliness of thereports and the disproportionately high levels of depreciation expenses reported in theoperating statement. The increased complexities of the financial management in LocalGovernment imposed by AAS 27 required professional accounting competencies moreappropriately derived from a degree level education which contributed to a highturnover of accounting staff during the four years. Finally, the paper questions theviability of the proposed dismantling of AAS 27 and the possible impact this might haveupon the sector.

  9. Safety and Feasibility of Autologous Mesenchymal Stem Cell Transplantation in Chronic Stroke in Indian patients. A four-year follow up.

    Science.gov (United States)

    Bhasin, Ashu; Kumaran, Senthil S; Bhatia, Rohit; Mohanty, Sujata; Srivastava, M V Padma

    2017-01-01

    Introduction: Stem cell (SC) therapy has been envisioned as a therapeutic vehicle to promote recovery in resistant neurological diseases. Knowing the logistics and paradigms in recovery processes after Stroke, clinicians have pioneered the transplantation therapy. This study presents four-year follow up of our previous trial transplanting bone-marrow-derived animal-free culture expanded intravenous mesenchymal stem cells (MSCs) in chronic stroke which was published in 2010. Methods: We performed an open-label, pilot trial on 12 patients with chronic stroke. Patients were allocated to two groups, those who received intravenous autologous ex vivo cultured mesenchymal stem cells (MSC group) or those who did not (control group), all followed for four years from the day of cell transplantation. Results: The reports have been optimistic regarding safety as we did not find any cell related side effects / mortality till 208th week. We observed that modified Barthel Index showed statistical significant improvement at 156 and 208 weeks of transplantation (95 % CI : -10.27 to 0.07; p =0.041) follow up in the MSC group as compared to controls. The 2nd and 3rd quartile for mBI in MSC group was 89 & 90 respectively suggesting good performance of patients in the stem cell group. The impairment scales i.e., Fugl Meyer, Ashworth tone scale, strength of hand muscles (MRC) did not show any significant improvement at 208th week which is similar to our previous published report. Conclusion: This follow up study primarily indicates safety, tolerance and applicability of autologous mesenchymal stem cells in Stroke. MSCs may act as "chaperones" or work through paracrine mechanisms leading to functional recovery post stroke.

  10. Behaviour of oceanic 137Cs following the Fukushima Daiichi Nuclear Power Plant accident for four years simulated numerically by a regional ocean model

    Science.gov (United States)

    Tsumune, D.; Tsubono, T.; Aoyama, M.; Misumi, K.; Tateda, Y.

    2015-12-01

    A series of accidents at the Fukushima Dai-ichi Nuclear Power Plant (1F NPP) following the earthquake and tsunami of 11 March 2011 resulted in the release of radioactive materials to the ocean by two major pathways, direct release from the accident site and atmospheric deposition.We reconstructed spatiotemporal variability of 137Cs activity in the regional ocean for four years by numerical model, such as a regional scale and the North Pacific scale oceanic dispersion models, an atmospheric transport model, a sediment transport model, a dynamic biological compartment model for marine biota and river runoff model. Direct release rate of 137Cs were estimated for four years after the accident by comparing simulated results and observed activities very close to the site. The estimated total amounts of directly release was 3.6±0.7 PBq. Directly release rate of 137Cs decreased exponentially with time by the end of December 2012 and then, was almost constant. Decrease rate were quite small after 2013. The daily release rate of 137Cs was estimated to be the order of magnitude of 1010 Bq/day by the end of March 2015. The activity of directly released 137Cs was detectable only in the coastal zone after December 2012. Simulated 137Cs activities attributable to direct release were in good agreement with observed activities, a result that implies the estimated direct release rate was reasonable. There is no observed data of 137Cs activity in the ocean from 11 to 21 March 2011. Observed data of marine biota should reflect the history of 137Cs activity in this early period. We reconstructed the history of 137Cs activity in this early period by considering atmospheric deposition, river input, rain water runoff from the 1F NPP site. The comparisons between simulated 137Cs activity of marine biota by a dynamic biological compartment and observed data also suggest that simulated 137Cs activity attributable to atmospheric deposition was underestimated in this early period. The

  11. Assessing the fate of antibiotic contaminants in metal contaminated soils four years after cessation of long-term waste water irrigation

    Energy Technology Data Exchange (ETDEWEB)

    Tamtam, Fatima, E-mail: fatima.tamtam@upmc.fr [Laboratoire Hydrologie et Environnement, EPHE, UMR Sisyphe 7619, UPMC-Paris 6, 4 place Jussieu, BC 105, 75252 Paris Cedex (France); Ecole des Hautes Etudes en Sante Publique (EHESP), Laboratoire d' Etude et de Recherche en Environnement et Sante (LERES), Avenue Professeur Leon Bernard, Rennes (France); Oort, Folkert van [Inra, UR 251, Physicochimie et Ecotoxicologie des SolS d' Agrosystemes Contamines (Pessac), RD 10, F-78026 Versailles Cedex (France); Le Bot, Barbara [Ecole des Hautes Etudes en Sante Publique (EHESP), Laboratoire d' Etude et de Recherche en Environnement et Sante (LERES), Avenue Professeur Leon Bernard, Rennes (France); Dinh, Tuc [Laboratoire Hydrologie et Environnement, EPHE, UMR Sisyphe 7619, UPMC-Paris 6, 4 place Jussieu, BC 105, 75252 Paris Cedex (France); Mompelat, Sophie [Ecole des Hautes Etudes en Sante Publique (EHESP), Laboratoire d' Etude et de Recherche en Environnement et Sante (LERES), Avenue Professeur Leon Bernard, Rennes (France); Chevreuil, Marc [Laboratoire Hydrologie et Environnement, EPHE, UMR Sisyphe 7619, UPMC-Paris 6, 4 place Jussieu, BC 105, 75252 Paris Cedex (France); Lamy, Isabelle [Inra, UR 251, Physicochimie et Ecotoxicologie des SolS d' Agrosystemes Contamines (Pessac), RD 10, F-78026 Versailles Cedex (France); Thiry, Medard [MinesParisTech, Centre de Geoscience, ENSMP, UMR Sisyphe 7619, 35 Rue St Honore, 77305 Fontainebleau (France)

    2011-01-01

    Spreading of urban wastewater on agricultural land may lead to concomitant input of organic and inorganic pollutants. Such multiple pollution sites offer unique opportunities to study the fate of both heavy metals and pharmaceuticals. We examined the occurrence and fate of selected antibiotics in sandy-textured soils, sampled four years after cessation of 100 years irrigation with urban wastewater from the Paris agglomeration. Previous studies on heavy metal contamination of these soils guided our sampling strategy. Six antibiotics were studied, including quinolones, with a strong affinity for organic and mineral soil components, and sulfonamides, a group of more mobile molecules. Bulk samples were collected from surface horizons in different irrigation fields, but also in subsurface horizons in two selected profiles. In surface horizons, three quinolones (oxolinic acid, nalidixic acid, and flumequine) were present in eight samples out of nine. Their contents varied spatially, but were well-correlated one to another. Their distributions showed great similarities regarding spatial distribution of total organic carbon and heavy metal contents, consistent with a common origin by wastewater irrigation. Highest concentrations were observed for sampling sites close to irrigation water outlets, reaching 22 {mu}g kg{sup -1} for nalidixic acid. Within soil profiles, the two antibiotic groups demonstrated an opposite behavior: quinolones, found only in surface horizons; sulfamethoxazole, detected in clay-rich subsurface horizons, concomitant with Zn accumulation. Such distribution patterns are consistent with chemical adsorption properties of the two antibiotic groups: immobilization of quinolones in the surface horizons ascribed to strong affinity for organic matter (OM), migration of sulfamethoxazole due to a lower affinity for OM and its interception and retention in electronegative charged clay-rich horizons. Our work suggests that antibiotics may represent a durable

  12. A hacker's guide to catching a debris flow: Lessons learned from four years of chasing mud in Colorado and southern California

    Science.gov (United States)

    Kean, J. W.; McCoy, S. W.; Staley, D. M.; Coe, J.; Leeper, R.; Tucker, G. E.

    2012-12-01

    Direct measurements of natural debris flows provide valuable insights into debris-flow processes and hazards. Yet debris flows are difficult to "catch" because they live in rugged terrain, appear infrequently, and have an appetite for destroying monitoring equipment. We present an overview of some successful (and failed) techniques we have used over the past four years to obtain direct measurements of 40+ debris flows in Colorado and southern California. Following the "MacGyver" theme of the session, we focus on the improvised equipment and methods we use in our hunt for quality data. These include an inexpensive erosion sensor to measure rates of debris-flow entrainment, a custom load cell enclosure for measuring debris-flow normal force, tracer rocks implanted with passive integrated transponders, basic pressure transducers to measure debris-flow timing, and standard digital cameras adapted to obtain high-resolution (1936 x 1288 pixels) video footage of debris flows. These techniques are also suitable for catching data on elusive flash floods. In addition, we also share some practical solutions to the logistical problems associated with installing monitoring equipment in rugged debris-flow terrain, such as suspension of non-contact stage gages high above channels.

  13. A long-term predictive validity study: can the CDI Short Form be used to predict language and early literacy skills four years later?

    Science.gov (United States)

    Can, Dilara Deniz; Ginsburg-Block, Marika; Golinkoff, Roberta Michnick; Hirsh-Pasek, Kathryn

    2013-09-01

    This longitudinal study examined the predictive validity of the MacArthur Communicative Developmental Inventories-Short Form (CDI-SF), a parent report questionnaire about children's language development (Fenson, Pethick, Renda, Cox, Dale & Reznick, 2000). Data were first gathered from parents on the CDI-SF vocabulary scores for seventy-six children (mean age=1 ; 10). Four years later (mean age=6 ; 1), children were assessed on language outcomes (expressive vocabulary, syntax, semantics and pragmatics) and code-related skills, including phonemic awareness, word recognition and decoding skills. Hierarchical regression analyses revealed that early expressive vocabulary accounted for 17% of the variance in picture vocabulary, 11% of the variance in syntax, and 7% of the variance in semantics, while not accounting for any variance in pragmatics in kindergarten. CDI-SF scores did not predict code-related skills in kindergarten. The importance of early vocabulary skills for later language development and CDI-SF as a valuable research tool are discussed.

  14. A characterization of intermediate-scale spread F structure from four years of high-resolution C/NOFS satellite data

    Science.gov (United States)

    Rino, Charles L.; Carrano, Charles S.; Groves, Keith M.; Roddy, Patrick A.

    2016-06-01

    Power law spectra have been invoked to interpret equatorial scintillation data for decades. Published analyses of intensity and phase scintillation data typically report power law spectra of the form q-p with 2.4 power law components. Strong scatter simulations and recent theoretical results have shown that two-component power law spectra can reconcile simultaneous equatorial scintillation observations from VHF to S-Band. The Communication/Navigation Outage Forecasting System (C/NOFS) satellite Planar Langmuir Probe generated a multiyear high-resolution sampling of equatorial spread F, but published analyses to date have reported only single-component power laws over scales from tens of kilometers to 70 m. This paper summarizes the analysis of high-resolution C/NOFS data collected over the four year period 2011 to 2014. Following an earlier investigation of several months of C/NOFS data by the authors of this paper, the extended data set revealed a pattern of occurrence of two-component spectra in the most highly disturbed data sets. The results confirm a known inverse correlation between turbulent strength and spectral index. The new results are interpreted as an equatorial spread F life cycle pattern with two-component spectra in the early development phase giving way to single-component spectra in the decay phase.

  15. Evaluation of the use of electronic health data to classify four-year mortality risk for older adults undergoing screening colonoscopies.

    Science.gov (United States)

    Synnestvedt, Marie B; Weiner, Mark G

    2011-01-01

    Current cancer screening recommendations often apply coarse age cutoffs for screening requirements without regard to predicted life expectancy. Using these cutoffs, healthier older patients may be under-screened, and sicker younger patients may be screened too often. Mortality risk classification using EHR data could be used to tailor screening reminders to physicians in ways that better align screening recommendations with patients who are more likely to live long enough to benefit from early detection. We have evaluated the performance of an existing prognostic index for 4-year mortality using data readily available in the electronic health record (EHR), and investigated the effect of the index in retrospective cohorts of adults age 65 and older undergoing screening colonoscopy. Risk scores in this adaptation of a four-year prognostic index were found to be associated with actual death rates and consistent with mortality rates from a national sample. Our results demonstrate that data extracted from electronic health records can be used to classify mortality risk. With improvements, including extension to a 5-year mortality model with inclusion of additional variables and extension of variable definitions, informatics methods to implement mortality models may prove to be clinically useful in tailoring screening guidelines.

  16. Timeline trend profile and seasonal variations in nicotine present in ambient PM10 samples: A four year investigation from Delhi region, India

    Science.gov (United States)

    Yadav, Shweta; Tandon, Ankit; Attri, Arun K.

    2014-12-01

    The detection of nicotine, an organic tracer for Environmental Tobacco Smoke (ETS), in the collected PM10 samples from Delhi region's ambient environment, in a appropriately designed investigation was initiated over four years (2006-2009) to: (1) Comprehend seasonal and inter-annual variations in the nicotine present in PM10; (2) Extract regression based linear trend profile manifested by nicotine in PM10; (3) Determine the non-linear trend timeline from the nicotine data, and compare it with the obtained linear trend; (4) Suggest the possible use of the designed experiment and analysis to have a qualitative appraisal of Tobacco Smoking activity in the sampling region. The PM10 samples were collected in a monthly time-series sequence at a known receptor site. Quantitative estimates of nicotine (ng m-3) were made by using a Thermal Desorption Gas Chromatography Mass Spectrometry (TD-GC/MS). The annual average concentrations of nicotine (ng m-3) were 516 ± 302 (2008) > 494 ± 301 (2009) > 438 ± 250 (2007) > 325 ± 149 (2006). The estimated linear trend of 5.4 ng m-3 month-1 corresponded to 16.3% per annum increase in the PM10 associated nicotine. The industrial production of India's tobacco index normalized to Delhi region's consumption, pegged an increase at 10.5% per annum over this period.

  17. In-situ infiltration performance of different permeable pavements in a employee used parking lot--A four-year study.

    Science.gov (United States)

    Kumar, Kuldip; Kozak, Joseph; Hundal, Lakhwinder; Cox, Albert; Zhang, Heng; Granato, Thomas

    2016-02-01

    Permeable pavements are being adopted as a green solution in many parts of the world to manage urban stormwater quantity and quality. This paper reports on the measured in-situ infiltration performance over a four-year period since construction and use of three permeable parking sections (permeable pavers, permeable concrete and permeable asphalt) of an employee car parking lot. There was only a marginal decline in infiltration rates of all three pavements after one year of use. However, between years two to four, the infiltration rates declined significantly due to clogging of pores either by dry deposition of particles and/or shear stress of vehicles driving and degrading the permeable surfaces; during the last two years, a greater decline was also observed in driving areas of the parking lots compared to parking slots, where minimal wear and tear are expected. Maintenance strategies were employed to reclaim some of the lost infiltration rate of the permeable pavements to limited success. Despite this decline, the infiltration rates were still four to five times higher than average rainstorm intensity in the region. Thus, these permeable pavement parking lots may have significant ecological importance due to their ability to infiltrate rainwater quickly, reduce the runoff in the catchment area, and also dampen runoff peak flows that could otherwise enter the collection system for treatment in a combined sewer area.

  18. Impact on practice of a British Association for Sexual Health and HIV Sexually Transmitted Infections Foundation (STIF) course: an audit of the first four years in Ireland.

    Science.gov (United States)

    Calamai, A; Howard, R; Kelly, R; Lambert, J

    2013-02-01

    In order to investigate the overall impact of the British Association for Sexual Health and HIV (BASHH) Sexually Transmitted Infections Foundation (STIF) course taught in Ireland since 2007, attendees were sent two questionnaires to investigate the overall impact of the course, its effect on clinical practice and the need for further education. Response rate was 19.4%. The majority found the course beneficial and that it did cover their practice needs (96.4%), with 83.6% saying that their confidence and technique in sexual history taking had improved. There was a 3.7% increase in the provision of HIV testing from precourse levels, although only 80% did so routinely; a 12.7% increase in syphilis testing; a 5.4% increase in testing for Chlamydia and a 12.7% increase for gonorrhoea. Some confusion seems to persist in relation to sexually transmitted infection (STI) risk factors. The second questionnaire tested STI knowledge. Most respondents scored well (average 81% correct answers); however, respondents who attended four years previously scored, on average, 7% worse than the others, suggesting the need for a periodic update in the area of STI education.

  19. The prevalence of Giardia intestinalis and Entamoeba histolytica/dispar in Van Regional Training and Research Hospital: A four-year monitoring

    Directory of Open Access Journals (Sweden)

    Yasemin Bayram

    2013-03-01

    Full Text Available Objective: The aim of this retrospective study was to determinethe frequency rates of Giardia and E.histolytica/E.dispar and their distribution by years as well as agegroups and gender distribution during a four-year period.Materials and methods: A total of 9911 stool samplessent to our laboratory between January 2008 and December2011 were tested for parasites. Native-Lugol and formolethyl acetate sedimentation methods were utilized formicroscopic identification of Entamoeba sp. and Giardiatrophozoites and cysts in fresh stool samples. Additionally,trichrome staining was performed in stool sampleswhere the distinctive diagnosis could not be confirmed.Results: From a total of 9911 stool samples analyzedduring the study, 4.7% were positive for Giardia and 6.2%were positive for Entemoeba histolytica/ Entemoeba dispar.Of Giardia-positive patients 57% were male and 43%female. Similarly, 56% of Entemoeba histolytica/ Entemoebadispar positive patients were male and 44% werefemale. Both parasites’ higher frequency rates seen inmale groups were found statistically significant (p<0.01.Conclusion: It is seen that intestinal protozoon infectionsare still present as an important public health problemin our region. In order to prevent this problem, personalhygiene and sanitation rules education for community aswell as infrastructure improvements are necessary.Key words: Giardia, Entemoeba histolytica/ Entemoeba dispar, prevalence

  20. Findings of a Four-Year Randomized Controlled Clinical Trial Comparing Two-Piece and One-Piece Zirconia Abutments Supporting Single Prosthetic Restorations in Maxillary Anterior Region

    Directory of Open Access Journals (Sweden)

    Guerino Paolantoni

    2016-01-01

    Full Text Available The purpose of this randomized controlled study is to investigate the clinical results obtained over four years and incidence of complications associated with one- versus two-piece custom made zirconia anchorages, in single tooth implant-supported restorations of the maxillary anterior region. Sixty-five patients, with a total of 74 missing maxillary teeth, were selected in the period from February 2007 to July 2010. Two different ways of custom made zirconia abutment and final prosthetic restoration were evaluated: a standard zirconia abutment associated with a pressed layer of lithium disilicate with an all-ceramic cemented restoration versus one-piece restoration with the facing porcelain fired and pressed straight to the custom made zirconia abutment. In 29 cases, the restoration consisted of an all-ceramic restoration for cementation (two pieces; in 45 cases the restoration was a screw-retained restoration (one piece. Three all-ceramic restorations broke during the observation time. Two one-piece restorations fractured after 26 months. At follow-up examination there were no significant differences between one-piece and two-piece groups regarding the PI, BI, and MBL. Awaiting studies with longer follow-up times, a careful conclusion is that zirconia anchorages for single-implant restorations seem to demonstrate good short-term technical and biological results.

  1. AIR QUALITY AND VARIATIONS IN PM10 POLLUTANT CONCENTRATION IN WESTERN IRAN DURING A FOUR -YEAR PERIOD (2008-2011, KERMANSHAH - A CASE STUDY

    Directory of Open Access Journals (Sweden)

    KIOMARS SHARAFI

    2015-01-01

    Full Text Available The present study explored the quality of PM10, over a four-year period in the western part of Iran. A total of 1334 samples were collected from air pollution measurement stations in Kermanshah. Statistical analysis was carried out using the SPSS ver.14. The results showed that the total percent change in PM10 over a period of 4 years was 10.04%, 59.2%, 26.4%, 0.7% and 3.3%. The highest and the lowest frequencies of PM10 occurred in February with 37.7%, June and July with 0%; winter and summer months with 21.96 and 4.81%, respectively. The results are depicted that the air quality in July, the summer months and 2008 was worst in terms of PM10 concentration, which was mainly due to the fluctuations and acute entrance of dust particles into western Iran. Hence, the reduction in such emissions is indispensable and requires extensive and considerable cooperation between the government of Iran and the neighbouring countries.

  2. Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia, and Hypertension in Japanese Population

    Science.gov (United States)

    Yamakado, Minoru; Nagao, Kenji; Imaizumi, Akira; Tani, Mizuki; Toda, Akiko; Tanaka, Takayuki; Jinzu, Hiroko; Miyano, Hiroshi; Yamamoto, Hiroshi; Daimon, Takashi; Horimoto, Katsuhisa; Ishizaka, Yuko

    2015-01-01

    Plasma free amino acid (PFAA) profile is highlighted in its association with visceral obesity and hyperinsulinemia, and future diabetes. Indeed PFAA profiling potentially can evaluate individuals’ future risks of developing lifestyle-related diseases, in addition to diabetes. However, few studies have been performed especially in Asian populations, about the optimal combination of PFAAs for evaluating health risks. We quantified PFAA levels in 3,701 Japanese subjects, and determined visceral fat area (VFA) and two-hour post-challenge insulin (Ins120 min) values in 865 and 1,160 subjects, respectively. Then, models between PFAA levels and the VFA or Ins120 min values were constructed by multiple linear regression analysis with variable selection. Finally, a cohort study of 2,984 subjects to examine capabilities of the obtained models for predicting four-year risk of developing new-onset lifestyle-related diseases was conducted. The correlation coefficients of the obtained PFAA models against VFA or Ins120 min were higher than single PFAA level. Our models work well for future risk prediction. Even after adjusting for commonly accepted multiple risk factors, these models can predict future development of diabetes, metabolic syndrome, and dyslipidemia. PFAA profiles confer independent and differing contributions to increasing the lifestyle-related disease risks in addition to the currently known factors in a general Japanese population. PMID:26156880

  3. Four-year comparison of water contents beneath a grass ley and a deciduous oak wood overlying Triassic sandstone in lowland England

    Science.gov (United States)

    Green, Julian C.; Reid, Ian; Calder, Ian R.; Nisbet, Thomas R.

    2006-09-01

    SummaryDifferences in the seasonal water dynamics of a sand soil overlying Triassic sandstone have been investigated to a depth of 9 m beneath both a grass ley and a pendunculate oak woodland within Clipstone Forest, Nottinghamshire, England. Fortnightly measurements with a neutron-probe over a four-year period allowed a comparison of the soil-rock water content to depths rarely reported. In spring, the rate of decrease of water content of the uppermost 2 m of soil was much greater under grass than oak woodland. In contrast, the rate of decrease under oak was greater after leafing out in May, while the rate of rewetting in early autumn was lower for this land-use until senescence and leaf-fall in late autumn. In the uppermost 2 m of soil - a depth that includes all plant roots - the soil moisture minima were between 47 and 58 mm lower under oak than grass in each year of monitoring. As a result of both these drier conditions and the comparatively late leaf fall of this species, penetration of the winter-season wetting front to 2 m was delayed by between one and three months at the oak site relative to grass in years of near-average rainfall. Rewetting at 9 m lags by 10-12 months, compared to the surface, giving an average penetration rate for the wetting front to this depth of 25-30 mm day -1, with little observable differences between the land-uses. Preferential flow is evident under both sites, affecting the profile to 3 m in all years and to at least 6 m following winters experiencing exceptional rainfall.

  4. Diabetic nephropathy as a cause of end-stage renal disease in Tabuk area, Saudi Arabia: A four-year study

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    Osama El Minshawy

    2014-01-01

    Full Text Available Diabetic nephropathy (DN as a cause of end-stage renal disease (ESRD is increa-sing worldwide. In some countries, it is the most common cause of ESRD. Our objective was to assess the incidence of DN as a cause of ESRD in Tabuk, to evaluate its changes in four years, and to compare the data of Tabuk with data from the United States (US to be aware of factors causing the difference. Data of ESRD patients with DN treated with renal replacement therapy (RRT was evaluated from 2009 to 2012. RRT was defined as ESRD patients who were treated either with chronic regular hemodialysis (HD, renal transplantation (Tx or continuous ambulatory peritoneal dialysis (PD. The incidence of DN as a cause of ESRD increased from 8% in 2009 to 18% in 2012. The mean age of this group was significantly higher than in patients on RRT due to other etiologies. Also, DN was more widespread in built-up areas than pastoral areas. The mortality rate decreased from 20% in 2009 to 14% in 2012. Despite this decrease, the mortality rate was still higher than that in patients on RRT due to other etiologies. When we restricted our analysis to patients treated by HD (76%, Tx (17% or PD (7%, the results were not significantly different. DN in the Tabuk area is rising, but is less widespread than in the US possibly because of an increased occurrence of other causes of ESRD or early loss of diabetic patients. Therefore, careful management of diabetic patients is obligatory.

  5. A four-year record of UK‧37- and TEX86-derived sea surface temperature estimates from sinking particles in the filamentous upwelling region off Cape Blanc, Mauritania

    Science.gov (United States)

    Mollenhauer, Gesine; Basse, Andreas; Kim, Jung-Hyun; Sinninghe Damsté, Jaap S.; Fischer, Gerhard

    2015-03-01

    Lipid biomarker records from sinking particles collected by sediment traps can be used to study the seasonality of biomarker production as well as processes of particle formation and settling, ultimately leading to the preservation of the biomarkers in sediments. Here we present records of the biomarker indices U37K ‧ based on alkenones and TEX86 based on isoprenoid glycerol dialkyl glycerol tetraethers (GDGTs), both used for the reconstruction of sea surface temperatures (SST). These records were obtained from sinking particles collected using a sediment trap moored in the filamentous upwelling zone off Cape Blanc, Mauritania, at approximately 1300 water depth during a four-year time interval between 2003 and 2007, and supplemented by U37K ‧ and TEX86 determined on suspended particulate matter collected from surface waters in the study area. Mass and lipid fluxes are highest during peak upwelling periods between October and June. The alkenone and GDGT records both display pronounced seasonal variability. Sinking velocities calculated from the time lag between measured SST maxima and minima and corresponding index maxima and minima in the trap samples are higher for particles containing alkenones (14-59 m d-1) than for GDGTs (9-17 m d-1). It is suggested that GDGTs are predominantly exported from shallow waters by incorporation in opal-rich particles. SST estimates based on the U37K ‧ index correspond to the amplitude observed fluctuations in SST during the study period. Temperature estimates based on TEX86 show smaller seasonal amplitudes, which can be explained by either predominant production of GDGTs during the warm season, or a contribution of GDGTs exported from deep waters, which are in this region known to carry GDGTs in a distribution that translates to a high TEX86 signal.

  6. Clinical outcome of monosegmental total disc replacement for lumbar disc disease with ball-and-socket prosthesis (Maverick): prospective study with four-year follow-up.

    Science.gov (United States)

    Van de Kelft, Erik; Verguts, Leo

    2012-01-01

    Arthrodesis is considered to be the reference treatment for degenerative disc disease (DDD), if the symptoms are refractory to conservative management. The drawback of arthrodesis is, besides a percentage of non-union, the reduced mobility that might generate an increased load and risk for degeneration of the adjacent levels. Total disc replacement (TDR) implants may overcome this problem. The long-term clinical effect and radiographic evaluation of motion preservation after implantation, however, have been subject to several nonconclusive studies. This study evaluated the long-term clinical and radiographic results and the safety of TDR with the Maverick prosthesis for surgical treatment of monosegmental DDD. TDR was performed in 50 consecutive patients with monosegmental DDD using the Maverick device. Patients were followed prospectively for disability, quality of life, pain intensity and frequency, as well as working status and return to sports, during 48 months. Motion preservation was assessed on neutral and dynamic radiographs at 48 months. The disability, pain intensity and frequency, and quality of life improved significantly at the 6-week follow-up, which was maintained over the full 48 months following Maverick implantation. Preoperatively, 80% of the patients stopped working and 86% halted sports activities. Four years after surgery, 85% of patients were again working and 79% took up their normal sports activities. Radiographic assessment showed that motion at the index level is maintained 48 months after TDR. No major complications were encountered. In this study, TDR with the Maverick prosthesis at one lumbar segment reduced pain and disability and improved quality of life as well as the general condition. Motion was preserved at the operated level, 48 months after surgery. The long-term effect on adjacent levels needs further follow-up. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Fuel cell powered by natural gas. The projet `Gazel` four years later; La pile a combustible au gaz naturel. Le projet `Gazel` apres quatre ans de exploitation

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, D.N. [Service de Gaz, Services Industriels de Geneve (Switzerland)

    1997-08-01

    The Services Industriels of Geneve (SIG) acted as a pioneer when in 1993 they purchased and commenced the operation of a first generation phosphoric acid fuel cell ONSI PC25A. The object of the SIG fuel cell pilot project, Gazel, is to promote the technology of fuel cells powered by natural gas, by demonstrating the feasibility of exploitation of the technique, and by seeking to optimize profitability conditions in an installation on an industrial scale. For almost four years, the operational results obtained conform to, and in some cases even exceed, the initial estimates, which were already very favourable in comparison with traditional technologies of electricity production. Indeed, ecological and technical performances more than corresponds to the manufacturer expectations. Long duration tests should allow to evaluate the profitability of the fuel cell, justly considered to be a technology of the future for the gas industry. (orig.) [Deutsch] Im Jahre 1993 haben die Industriellen Betriebe in Genf (SIG) auf eigene Rechnung die Brennstoffzelle PC25A von ONSI erworben und als erste deren regulaeren Betrieb aufgenommen. Mit diesem Projekt hatten die SIG sich zum Ziel gesetzt, die Brennstoffzellen-Technologie zu lancieren. Erdgas wird zur Speisung der Brennstoffzelle benutzt, und das Projekt ist eine Demonstration des zuverlaessigen Betriebs dieser Technologie, mit dem im industriellen Massstab die Rentabilitaetsbedingungen reell optimiert werden. Die in den beinahe vier Jahrzehnten Betriebsdauer erzielten resultate entsprechen voll den Erwartungen und uebertreffen in einzelnen Details die urspruenglichen Vorgaben, die im Vergleich zu den herkoemmlichen Technologien der Elektrizitaetserzeugung bereits sehr viel guenstiger sind. Den an sie gestellten technischen und oekologischen Forderungen von Seiten des Herstellers hat die realisierte Anlage tatsaechlich voellig entsprochen. Langzeitversuche dieser Art sind ideal, um die Rentabilitaet der Brennstoffzelle

  8. Lower Protein-to-Carbohydrate Ratio in Maternal Diet is Associated with Higher Childhood Systolic Blood Pressure up to Age Four Years

    Directory of Open Access Journals (Sweden)

    Michelle L. Blumfield

    2015-04-01

    Full Text Available The prenatal environment can influence development of offspring blood pressure (BP, which tracks into adulthood. This prospective longitudinal study investigated whether maternal pregnancy dietary intake is associated with the development of child BP up to age four years. Data are from 129 mother-child dyads enrolled in the Women and Their Children’s Health study. Maternal diet was assessed using a validated 74-item food frequency questionnaire at 18 to 24 weeks and 36 to 40 weeks, with a reference period of the previous three months. Child systolic and diastolic BP were measured at 3, 6, 9, 12, 24, 36 and 48 months, using an automated BP monitor. Using mixed-model regression analyses adjusted for childhood growth indices, pregnancy intakes of percentage of energy (E% polyunsaturated fat (β coefficient 0.73; 95% CI 0.003, 1.45; p = 0.045, E% omega-6 fatty acids (β coefficient 0.89; 95% CI 0.09, 1.69; p = 0.03 and protein-to-carbohydrate (P:C ratio (β coefficient −14.14; 95% CI −27.68, −0.60; p = 0.04 were associated with child systolic BP trajectory up to 4 years. Child systolic BP was greatest at low proportions of dietary protein (<16% of energy and high carbohydrate (>40% of energy intakes. There may be an ideal maternal macronutrient ratio associated with optimal infant BP. Maternal diet, which is potentially modifiable, may play an important role in influencing offspring risk of future hypertension.

  9. Inflammation and renal function after a four-year follow-up in subjects with unimpaired glomerular filtration rate: results from the observational, population-based CARLA cohort.

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    Daniel Medenwald

    Full Text Available There is evidence that chronic inflammation is associated with the progression/development of chronic renal failure; however, relations in subjects with preserved renal function remain insufficiently understood.To examine the association of inflammation with the development of renal failure in a cohort of the elderly general population.After excluding subjects with reduced estimated glomerular filtration rate (eGFR<60 mL/min/1.73 m2 and missing data, the cohort incorporated 785 men and 659 women (aged 45-83 years. Follow-up was performed four years after baseline. Covariate adjusted linear and logistic regression models were used to assess the association of plasma/serum concentrations of soluble tumour necrosis factor receptor 1 (sTNF-R1, C-reactive protein (CRP, and interleukin 6 (IL-6 with change in eGFR/creatinine. The areas under the curve (AUCs from receiver operating characteristics (ROCs were estimated.In adjusted models sTNF-R1 was distinctively associated with a decline in eGFR in men (0.6 mL/min/1.73 m2 per 100 pg/mL sTNF-R1; 95% CI: 0.4-0.8, but not in women. A similar association could not be found for CRP or IL-6. Estimates of sTNF-R1 in the cross-sectional analyses were similar between sexes, while CRP and IL-6 were not relevantly associated with eGFR/creatinine.In the elderly male general population with preserved renal function sTNF-R1 predicts the development of renal failure.

  10. Early Diagnosis and Intervention for Hearing Loss in Newborns Discharged from Intensive Care Units: a Four-year Follow-up Study in North of Iran

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    Sima Tajik

    2016-08-01

    Full Text Available Background Hearing loss is the most common congenital disorder the incidence of which is further increased in the presence of risk factors for hearing loss among newborns admitted to the neonatal intensive care unit (NICU. The aim of this study was early diagnosis and intervention for hearing loss in newborns discharged from NICU. Materials and Methods This prospective cohort study was conducted on 3,362 newborns discharged from the NICU in several hospitals in Babol, Iran. Each newborn was evaluated through the transient evoked otoacoustic emission (T EOAE test. In the absence of any result, retests including TEOAE and diagnostic auditory brainstem response (ABR were conducted. In case of hearing loss, intervention programs including hearing aids fitting and cochlear implant were considered for infants. Each newborn infant was follow-up for four years. The infant’s age was also calculated during the hearing loss diagnosis and the intervention program. Results Sensorineural hearing loss (SNHL was diagnosed in 35 (1.04% of the infants at an average age of 105.65 + 96.72 days. Most of hearing loss diagnosis (51.43% was before the age of 3 months. Hearing aids were fitted for 25 infants (80.64% with a mean age of 9.61 + 7.64 months. Cochlear implants were done for two (8% children. At the end of the follow up, all of the children except one case (3.22% were able to use verbal communication. Conclusion Hearing screening of the high risk NICU graduate babies has reduced the age of hearing loss diagnosis to 3 months. The presence of severe to profound hearing loss in this population highlights the importance of early diagnosis and intervention.

  11. Benefits of ultra-fast-track anesthesia in left ventricular assist device implantation: a retrospective, propensity score matched cohort study of a four-year single center experience.

    Science.gov (United States)

    Zayat, Rashad; Menon, Ares K; Goetzenich, Andreas; Schaelte, Gereon; Autschbach, Ruediger; Stoppe, Christian; Simon, Tim-Philipp; Tewarie, Lachmandath; Moza, Ajay

    2017-02-08

    The use of left ventricular assist devices (LVADs) has gained significant importance for treatment of end-stage heart failure. Fast-track procedures are well established in cardiac surgery, whereas knowledge of their benefits after LVAD implantation is sparse. We hypothesized that ultra-fast-track anesthesia (UFTA) with in-theater extubation or at a maximum of 4 h. after surgery is feasible in Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) level 3 and 4 patients and might prevent postoperative complications. From March, 2010 to March, 2012, 53 LVADs (50 Heart Mate II and 3 Heart Ware) were implanted in patients in our department. UFTA was successfully performed (LVAD ultra ) in 13 patients. After propensity score matching, we compared the LVAD ultra group with a matched group (LVAD match ) receiving conventional anesthesia management. Patients in the LVAD ultra group had significantly lower incidences of pneumonia (p = 0.031), delirium (p = 0.031) and right ventricular failure (RVF) (p = 0.031). They showed a significantly higher cardiac index in the first 12 h. (p = 0.017); a significantly lower central venous pressure during the first 24 h. postoperatively (p = 0.005) and a significantly shorter intensive care unit (ICU) stay (p = 0.016). Kaplan-Meier analysis after four years of follow-up showed no significant difference in survival. In this pilot study, we demonstrated the feasibility of ultra-fast-track anesthesia in LVAD implantation in selected patients with INTERMACS level 3-4. Patients had a lower incidence of postoperative complications, better hemodynamic performance, shorter length of ICU stay and lower incidence of RVF after UFTA. Prospective randomized investigations should examine the preservation of right ventricular function in larger numbers and identify appropriate selection criteria.

  12. Microbial Diversity and Metal Speciation Changes in Mine Tailings Following Compost-Assisted Direct Planting: A Four-Year Superfund Site Field Study

    Science.gov (United States)

    Maier, R. M.; Gil-Loaiza, J.; Honeker, L. K.; Hottenstein, J. D.; Valentin-Vargas, A.; Jennings, L. L.; Hammond, C.; Neilson, J. W.; Root, R. A.; Chorover, J.

    2015-12-01

    EPA estimates that future mine tailings remediation costs will exceed US $50 billion using present technologies based on constructing an inert or biological cap on the tailings. Both approaches require large amounts of capping materials that can be difficult and expensive to obtain especially for sites several thousand hectares in size. An alternative technology is direct planting into tailings. However, direct planting alone is not feasible for many legacy sites due to extreme acidity and high metal content which prevent plant germination and growth. Therefore the process must be "assisted" through the addition of amendments such as compost. Here we present results from the first four years of a field study at the Iron King Mine and Humboldt Smelter Superfund site demonstrating the feasibility of compost-assisted direct planting. Parameters measured during the field study included: canopy cover, pH, nutrient content, plant metal uptake, metal(loid) speciation, mineral analysis, microbiome analysis, and plant root-metal-microbe interactions. Integrated analysis of these parameters suggests that even in this "worst-case scenario" mine tailings site (pH 2.5; As and Pb each exceeding 2 g kg-1), we have created a sustainable system. In this system, phyto-catalyzed stabilization of inorganic contaminants in the root zone is driven by plant root exudates and the associated rhizosphere microbial community. The results of this research will be put into context of a larger topic- that of ecological engineering of mine tailings sites - a technique being proposed to prevent creation of acidic conditions and metal(loid) mobilization in the first place.

  13. Pediatric Epidemic of Salmonella enterica Serovar Typhimurium in the Area of L’Aquila, Italy, Four Years after a Catastrophic Earthquake

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    Giovanni Nigro

    2016-05-01

    Full Text Available Background: A Salmonella enterica epidemic occurred in children of the area of L’Aquila (Central Italy, Abruzzo region between June 2013 and October 2014, four years after the catastrophic earthquake of 6 April 2009. Methods: Clinical and laboratory data were collected from hospitalized and ambulatory children. Routine investigations for Salmonella infection were carried out on numerous alimentary matrices of animal origin and sampling sources for drinking water of the L’Aquila district, including pickup points of the two main aqueducts. Results: Salmonella infection occurred in 155 children (83 females: 53%, aged 1 to 15 years (mean 2.10. Of these, 44 children (28.4% were hospitalized because of severe dehydration, electrolyte abnormalities, and fever resistant to oral antipyretic and antibiotic drugs. Three children (1.9% were reinfected within four months after primary infection by the same Salmonella strain. Four children (2.6%, aged one to two years, were coinfected by rotavirus. A seven-year old child had a concomitant right hip joint arthritis. The isolated strains, as confirmed in about the half of cases or probable/possible in the remaining ones, were identified as S. enterica serovar Typhimurium [4,5:i:-], monophasic variant. Aterno river, bordering the L’Aquila district, was recognized as the main responsible source for the contamination of local crops and vegetables derived from polluted crops. Conclusions: The high rate of hospitalized children underlines the emergence of a highly pathogenic S. enterica strain probably subsequent to the contamination of the spring water sources after geological changes occurred during the catastrophic earthquake.

  14. Exploration and Practice of Four -year Vocational Education%四年制职业教育的探索与实践

    Institute of Scientific and Technical Information of China (English)

    孙小红

    2015-01-01

    国家社会经济发展和构建现代职业教育体系对高端技能型人才的培养提出了迫切的要求。本文在广泛调研、分析的基础上,确定了四年制高职的人才培养目标和课程体系,以本科与高职院校联合培养应用型、高端技能型人才试点班为契机,对组织保证、学业导师、教学管理和监督等创新性教学管理模式进行了有益的尝试,将人才培养方案转化成培养成果,为高层次职业教育开创了先河。%the social and economic development of the state and the construction of modern voca‐tional education system impose urgent requirements for cultivating the high-end skilled personnel .This paper defines the objectives and curricular of cultivating four -year higher vocational personnel through comprehensive investigation and research .It takes the opportunities of jointly cultivating practical and high-end skilled personnel by universities and higher vocational colleges to make rewarding attempts in organizational guarantee , academic advisor , teaching management ,supervision and other innovative teaching management patterns and converts the personnel training program to the training results and creates the precedent for higher vocational education .

  15. Temperature and moisture conditions for life in the extreme arid region of the Atacama desert: four years of observations including the El Nino of 1997-1998

    Science.gov (United States)

    McKay, Christopher P.; Friedmann, E. Imre; Gomez-Silva, Benito; Caceres-Villanueva, Luis; Andersen, Dale T.; Landheim, Ragnhild

    2003-01-01

    The Atacama along the Pacific Coast of Chile and Peru is one of the driest and possibly oldest deserts in the world. It represents an extreme habitat for life on Earth and is an analog for life in dry conditions on Mars. We report on four years (September 1994-October 1998) of climate and moisture data from the extreme arid region of the Atacama. Our data are focused on understanding moisture sources and their role in creating suitable environments for photosynthetic microorganisms in the desert surface. The average air temperature was 16.5 degrees C and 16.6 degrees C in 1995 and 1996, respectively. The maximum air temperature recorded was 37.9 degrees C, and the minimum was -5.7 degrees C. Annual average sunlight was 336 and 335 W m(-2) in 1995 and 1996, respectively. Winds averaged a few meters per second, with strong fohn winds coming from the west exceeding 12 m s(-1). During our 4 years of observation there was only one significant rain event of 2.3 mm, which occurred near midnight local time. We suggest that this event was a rainout of a heavy fog. It is of interest that the strong El Nino of 1997-1998 brought heavy rainfall to the deserts of Peru, but did not bring significant rain to the central Atacama in Chile. Dew occurred at our station frequently following high nighttime relative humidity, but is not a significant source of moisture in the soil or under stones. Groundwater also does not contribute to surface moisture. Only the one rain event of 2.3 mm resulted in liquid water in the soil and beneath stones for a total of only 65-85 h over 4 years. The paucity of liquid water under stones is consistent with the apparent absence of hypolithic (under-stone) cyanobacteria, the only known primary producers in such extreme deserts.

  16. Pre- and postnatal exposure of children to tobacco smoke during the first four years of life – observations of the authors

    Directory of Open Access Journals (Sweden)

    Barbara Kamer

    2014-11-01

    Full Text Available [b]Introduction[/b]. Environmental exposure to tobacco smoke is a significant threat for human health, where the higher is its degree, the more immature the human organism is. Therefore, the exposure to Tobacco smoke in foetal life exerts unfavourable effects on developing foetus and may cause early and distant results in children. [b]Material and methods.[/b] The study comprised 318 children in their first four years of life, treated for various medical conditions. The examined children were divided into two groups, Group 1 – children exposed to Tobacco smoke – and Group 2 – a control group with children from non-smoking families. History data were obtained on the basis of a specially designed questionnaire, used by the doctor in an individual conversation with parent. In each third child from the group 1 cotinine concentration in urine was assayed by the method of high performance liquid chromatography-UV-VIS and the cotinine/creatinine ratio was calculated. [b]Results of stud[/b][b]y[/b]. Results demonstrated environmental exposure to tobacco smoke in 173 children (Group 1. Out of them 31.2% were the children whose mothers had smoked also during pregnancy (Subgroup A. The other 119 children from Group 1 were accounted to Subgroup B, i.e., children, where other household members had been smoking cigarettes. A comparative group comprised 143 children from non-smoking families. The results demonstrated then that 17% of all the examined children were those, exposed to tobacco smoke effects already in their foetal life, predisposing them to prematurity and low birth weight. Moreover, it was observed that the young age and lower education level of their parents, together with worse housing conditions, may suggest a predisposing character and role of the mentioned factors.

  17. Radiotherapy Breast Boost With Reduced Whole-Breast Dose Is Associated With Improved Cosmesis: The Results of a Comprehensive Assessment From the St. George and Wollongong Randomized Breast Boost Trial

    Energy Technology Data Exchange (ETDEWEB)

    Hau, Eric, E-mail: helloerico@yahoo.com [Cancer Care Centre, St. George Hospital, Kogarah, Sydney (Australia); Browne, Lois H.; Khanna, Sam; Cail, Stacy; Cert, Grad; Chin, Yaw; Clark, Catherine; Inder, Stephanie; Szwajcer, Alison; Graham, Peter H. [Cancer Care Centre, St. George Hospital, Kogarah, Sydney (Australia)

    2012-02-01

    Purpose: To evaluate comprehensively the effect of a radiotherapy boost on breast cosmetic outcomes after 5 years in patients treated with breast-conserving surgery. Methods: The St. George and Wollongong trial (NCT00138814) randomized 688 patients with histologically proven Tis-2, N 0-1, M0 carcinoma to the control arm of 50 Gy in 25 fractions (342 patients) and the boost arm of 45 Gy in 25 fractions to the whole breast followed by a 16 Gy in 8 fraction electron boost (346 patients). Five-year cosmetic outcomes were assessed by a panel subjectively in 385 patients and objectively using pBRA (relative breast retraction assessment). A subset of patients also had absolute BRA measurements. Clinician assessment and patient self-assessment of overall cosmetic and specific items as well as computer BCCT.core analysis were also performed. Results: The boost arm had improved cosmetic overall outcomes as scored by the panel and BCCT.core software with 79% (p = 0.016) and 81% (p = 0.004) excellent/good cosmesis respectively compared with 68% in no-boost arm. The boost arm also had lower pBRA and BRA values with a mean difference of 0.60 and 1.82 mm, respectively, but was not statistically significant. There was a very high proportion of overall excellent/good cosmetic outcome in 95% and 93% in the boost and no-boost arms using patient self-assessment. However, no difference in overall and specific items scored by clinician assessment and patient self-assessment was found. Conclusion: The results show the negative cosmetic effect of a 16-Gy boost is offset by a lower whole-breast dose of 45 Gy.

  18. Tile drain losses of nitrogen and phosphorus from fields under integrated and organic crop rotations. A four-year study on a clay soil in southwest Sweden.

    Science.gov (United States)

    Stenberg, Maria; Ulén, Barbro; Söderström, Mats; Roland, Björn; Delin, Karl; Helander, Carl-Anders

    2012-09-15

    In order to explore the influence of site-specific soil properties on nitrogen (N) and phosphorus (P) losses between individual fields and crop sequences, 16 drained fields with clay soils were investigated in a four-year study. Mean total N (TN) loss was 6.6-11.1 from a conventional, 14.3-21.5 from an organic and 13.1-23.9 kg ha(-1) year(-1) from an integrated cropping system across a 4 year period, with 75% in nitrate form (NO(3)-N). Mean total P (TP) loss was 0.96-3.03, 0.99-4.63 and 0.76-2.67 kg ha(-1) year(-1), from the three systems respectively during the same period, with 25% in dissolved reactive form (DRP). Median N efficiency was calculated to be 70% including gains from estimated N fixation. According to principal component factor (PCA) analysis, field characteristics and cropping system were generally more important for losses of N and P than year. Accumulation of soil mineral N in the autumn and (estimated) N fixation was important for N leaching. No P fertilisers were used at the site in either cropping system. Total P concentration in drainage water from each of the fields was marginally significantly (p<0.05) correlated to TP concentration in the topsoil (r=0.52), measured in hydrochloric acid extract (P-HCl). Mean DRP concentrations were significantly (p<0.01) correlated to degree of P saturation (DPS-AL) and soil carbon (C) content in the topsoil (r=0.63). Good establishment of a crop with efficient nutrient uptake and good soil structure was general preconditions for low nutrient leaching. Incorporation of ley by tillage operations in the summer before autumn crop establishment and repeated operations in autumn as well, increased N leaching. Crop management in sequences with leguminous crops needs to be considered carefully when designing cropping systems high efficiency in N utilisation and low environmental impact. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. Characteristics of Four-years of GOSAT/TANSO-FTS TIR V1.0 CO2 and CH4 Products

    Science.gov (United States)

    Saitoh, N.; Kimoto, S.; Sugimura, R.; Imasu, R.; Shiomi, K.; Kuze, A.; Kataoka, F.; Knuteson, R. O.; Machida, T.; Sawa, Y.; Matsuda, H.

    2015-12-01

    Greenhouse Gases Observing Satellite (GOSAT) was launched on 23 January 2009, and has continued to make global observations, including both nadir and off-nadir measurements, for more than six years since its launch. The thermal infrared (TIR) band of Thermal and Near-infrared Sensor for Carbon Observation Fourier Transform Spectrometer (TANSO-FTS) on board the GOSAT has observed CO2 and CH4 profiles. We have analyzed the four-year data from 2010 through 2013 of the latest released version of the TIR Level 2 (L2) CO2 and CH4 products (V1.0). Comparisons of the TIR upper atmospheric CO2 product with CO2 data from Comprehensive Observation Network for Trace Gases by Airliner (CONTRAIL) aircraft measurements show that the growth rate estimated from the TIR CO2 data is slightly lower than that from the CONTRAIL data. Overall, the TIR V1.0 CO2 product has better quality in the upper troposphere and lower stratosphere than the a priori judging from comparisons with the collocated aircraft data. In spring and summer, however, the quality of the TIR L2 CO2 products became slightly worse than in the other seasons, especially in the low and northern-mid latitudes. This is because the corresponding a priori had a larger bias and the TIR Level 1B (L1B) radiance spectra might have a larger bias in the spring-summer seasons. Here, we have tested several types of correction methods to modify the L1B spectral bias, and then compared CO2 and CH4 concentrations retrieved after applying spectral bias correction factors with coincident CONTRAIL and HIAPER Pole-to-Pole Observation (HIPPO) aircraft data. The comparison results suggest that the L1B spectral bias correction factor should be changed depending on wavelength. In addition, it should be expressed as a function of on-board internal calibration blackbody temperatures. This is because they are weak season-dependent parameters; they were clearly lower in spring and summer.

  20. Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicine.

    Science.gov (United States)

    Oladipo, Oladosu O; Wellington, Oyibo A; Sutherland, Colin J

    2015-04-28

    In Nigeria, despite the change in National malaria drug policy to artemisinin combination therapy (ACT) in 2005 due to widespread chloroquine resistance, chloroquine (CQ) is still widely used in the treatment of malaria because it is cheap, affordable and accessible. The use of ACT for the management of uncomplicated malaria is currently being promoted. The employment of genetic markers to track circulating chloroquine-resistant parasites are useful in elucidating likely poor efficacy of chloroquine, especially in settings where it is not recommended for the treatment of uncomplicated falciparum malaria. This study determined the prevalence of pfcrt haplotypes and point mutations in pfmdr1 genes four years after the change in antimalarial treatment policy from CQ to the ACTs in Lagos, a commercial city in South-West, Nigeria. This was a cross sectional study on uncomplicated malaria in children less than 12 years that presented with fever and other symptoms suggestive of malaria. Parasite DNA was extracted from 119 patients out of 251 children who were positive for Plasmodium falciparum by microscopy and amplified. The occurrence of haplotypes was investigated in pfcrt gene using probe-based qPCR and single nucleotide polymorphisms in pfmdr1 gene using nested PCR. One hundred and nine (109) of the 119 children with P falciparum infection (91.6%) harbourd parasites with the mutant pfcrt haplotype (CVIET). Out of this, 4.2% comprised a mixture of genotypes encoding CVMNK and CVIET, while 4.2% had the wild type (CVMNK). Furthermore, the frequency of point mutations in pfmdr1 was 62.2% and 69.0% for codons Y86 and F184 respectively. There were no mutations at codons 1034, 1042 and 1246 of the Pfmdr1 genes. The high frequency of the CQ-resistant haplotypes (CVIET) and mutations in Pfmdr1 associated with CQ resistance in P. falciparum among these children suggest that CQ-resistant parasites are still in circulation. Continuous use of chloroquine may continue to increase

  1. Photovoltaic private project at the Energy research Centre of the Netherlands (ECN). Four years of experience; PV-prive project bij ECN. Vier jaar ervaring

    Energy Technology Data Exchange (ETDEWEB)

    Jablonska, B.; Van Dijk, A.L.; Kaan, H.F.; Van Leeuwen, M.; De Boer, G.T.M.

    2004-10-01

    will continue at least for a period of five years. For this purpose, ECN has developed its own monitoring software. This software has also been used within other projects. The report treats the issue of compensation for the electricity supplied to the grid and the issue of electricity meters with registers turning backwards. Within the period of four years, a lot valuable knowledge has been gathered. This has been reached through continuous monitoring of practical experience since the beginning of the project as well as gaining information on non-technical aspects and operation of PV-systems by means of a questionnaire. The helpdesk and the service that shall stay available for five years have certainly contributed to this. Looking at all this experience it is clear that the project may be evaluated as successful. [Dutch] Het ECN PV-Prive project is opgezet om de toepassing van kleine netgekoppelde PV-systemen op bestaande woningen te onderzoeken. De ECN en NRG medewerkers hebben een mogelijkheid gekregen om een SunPower PV-systeem aan te schaffen in het kader van een aantrekkelijke financiele regeling. In ruil voor dit aanbod zouden zij aan het monitoringsproject meewerken en de opbrengsten van hun PV-systemen regelmatig aan ECN doorgeven. De rol van ECN in dit project is het monitoren en verspreiden van de ervaring opgedaan in de periode van de voorbereiding, installatie, nazorg en het gebruik van PV-systemen, alsook het verlenen van service en verstrekken van de informatie aan de deelnemers. Het monitoren van de opbrengsten en de kwaliteit van de PV-systemen is een uitgangspunt geweest voor vervolgonderzoeksprojecten. Binnen het PV-Prive project hebben 48 medewerkers van ECN en NRG een PV-systeem laten installeren. Na ruim drie jaar, tot en met juni 2004, is deze groep tot 36 deelnemers geslonken omdat een aantal deelnemers uit dienst is of het huis met het PV-systeem verkocht heeft. Of er een vergunning voor het plaatsen van het PV-systeem verleend werd, hing sterk

  2. Factors Influencing Pre-Service Science Teachers' Perception of Computer Self-Efficacy

    Science.gov (United States)

    Hakverdi, Meral; Gucum, Berna; Korkmaz, Hunkar

    2007-01-01

    This study examined the factors influencing pre-service teachers' perceptions of computers' self- efficacy. Participants in the study were 305 pre-service science teachers at a four-year public university in Turkey. Two instruments were used for this study: the Turkish version of the Microcomputer Utilization in Teaching Efficacy Beliefs…

  3. A four-year survey in the farming region of Chile, occurrence and human exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans, and dioxin -like polychlorinated biphenyls in different raw meats

    NARCIS (Netherlands)

    San Martin, B.V.; Pizarro-Aránguiz, N.; García-Mendoza, D.; Araya-Jordan, C.; Maddaleno, A.; Abad, E.; Galbán-Malagón, C.J.

    2016-01-01

    For the first time in South America, a four-year survey (2011-2014) was conducted to assess the occurrence of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in different raw meats (bovine, pork, ovine, chicken, and turkey) sampled from

  4. Transfer Students from California Community Colleges: A Narrative Approach to Understanding the Social Capital and Institutional Factors That Lead to a Timely Transfer to a Public, Four-Year University

    Science.gov (United States)

    Hermoso, Katrina Virata

    2013-01-01

    The unique experiences of community college transfer students have not been explored at public, four-year universities. Most of the research on the experiences of community college students is based on quantitative research methods, which fail to provide a comprehensive understanding of the nature of students' lived experiences. This qualitative…

  5. Four-Year Durability of Initial Combination Therapy with Sitagliptin and Metformin in Patients with Type 2 Diabetes in Clinical Practice; COSMIC Study.

    Directory of Open Access Journals (Sweden)

    Eu Jeong Ku

    Full Text Available We investigated the efficacy of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes for 4 years in clinical practice.Between 2009 and 2010, we reviewed 1,178 patients with type 2 diabetes (HbA1c ≥7.5% or 58 mmol/mol prescribed initial combination therapy with sitagliptin and metformin. After excluding 288 patients without a second follow-up, 890 individuals (age, 58.0 ± 12.5 years; BMI, 25.4 ± 3.5 kg/m2; HbA1c, 8.6 ± 1.1% were followed up with every 3-6 months for 4 years. Homeostasis model assessments for insulin resistance and β-cell function (HOMA-β were recorded at baseline. The response criterion was HbA1c reduction by ≥0.8% from baseline or attainment of the target HbA1c (≤7.0% or 53 mmol/mol. At the end of every year of treatment, changes in HbA1c from the baseline were assessed.After 1 year, 72.2% of patients with initial combination therapy had responded, defined as HbA1c reduction ≥0.8% or attainment of the target HbA1c ≤7.0%. After 4 years, 35.4% of the patients still showed a response, with an HbA1c level of 7.0 ± 0.9%. A high HbA1c level at baseline was the most significant independent predictor of the long-term response (P<0.001. In addition, low HOMA-β was a significant predictor of a greater reduction in HbA1c. This treatment was generally well tolerated over the 4-year follow-up period, without any serious adverse events.This real-world follow-up study shows a persistent glucose-reducing effect of initial combination therapy with sitagliptin and metformin for up to 4 years.

  6. Toothbrushing efficacy

    NARCIS (Netherlands)

    Rosema, N.A.M.

    2015-01-01

    This thesis will explore the most meaningful aspects which are considered to be of interest regarding the efficacy of toothbrushes. One could discuss efficacy by means of plaque removal as well as by means of the effect on gingival inflammation. Plaque removal may be considered as a surrogate effect

  7. Neonatal Intestinal Obstruction-Four Year Experience

    Directory of Open Access Journals (Sweden)

    D. Rathore

    2015-06-01

    Full Text Available Aim of study: To study the aetiology and frequency, sex incidence, age of presentation, management and outcome of neonatal intestinal obstruction. Material and Methods: This prospective study of 316 neonates with intestinal obstruction was conducted over a period of 4 years from November 2009 to October 2013 at single institute. These cases were managed by various surgical procedures. Their epidemiology, day of presentation, associated anomalies and outcomes were studied. Results: A total of 316 neonates (277 males and 39 females were operated for intestinal obstruction. 268(84.81% neonates presented in the 1st week of life. Imperforate anus occurred in 206 (65.19%.Small bowel atresia accounted for23 (7.27% cases while duodenal atresia was seen in19 (6.01% patients. Infantile hypertrophic pyloric stenosis and Malrotation each occurred in 14 (4.43% patients; Hirschsprung’s disease in 18(5.69%, Necrotising Enterocolitis in 12(3.79%, Meconium disease of newborn in 9(2.85% while colonic atresia was seen in one (0.3% patient. Colostomy was performed in 145(45.88%, Pouchostomy in 15(4.74% and Cutback anoplasty in 56(17.72% patients. Ramsted’s Pyloromyotomy in 13(4.11%% neonates, Laparoscopic Pyloromyotomy in 1(0.3%,Kimura’s Duodenoduodenostomy in 19(6.01% ,End to Back anastomosis in 24(7.59% , End to End anastomosis in 7(2.21% , Multiple anastomosis in 2(0.6% , Enterotomy with irrigation in 7(2.21% , Ladd’s procedure in 14(4.43% , ,Single stage transanal pull through in 8(2.53% , Ileostomy in 2(0.6% , Single stage Abdominoperineal pull through in 2(0.6%, Levelling colostomy in 6(1.89% ,Peritoneal drain insertion under Local anaesthesia in 5(1.58% . Overall mortality was 13.60%. Conclusion: Intestinal Obstruction is the most common surgical emergency in neonatal period. Early and accurate diagnosis is paramount for proper patient management. The etiology, mode of presentation, morbidity and outcome of surgery of intestinal obstruction in neonates in our study were not significantly different from other studies.

  8. Four years of membership / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2008-01-01

    Tagasivaade Eesti nelja-aastasele liikmelisusele Euroopa Liidus ja NATO-s. Juuresoleval fotol Eesti president Toomas Hendrik Ilves ja Läti president Valdis Zatlers Valgas/Valkas enne Eesti ja Läti vahelise piiritõkke eemaldamist seoses Schengeni õigusruumi laienemisega, 21. detsember 2007

  9. Evaluating Four Years of ID Experience.

    Science.gov (United States)

    Miles, Gearold D.

    1983-01-01

    Describes the introduction of professionally qualified instructional designers into the Professional Education Division of Arthur Anderson and Co., an international public accounting and professional services firm. The difficulties and misunderstandings that were overcome and the role the instructional designers now play in providing training…

  10. Multicystic Dysplastic Kidney: Four-Year Evaluation

    Directory of Open Access Journals (Sweden)

    Berna AYTAÇ

    2011-09-01

    Full Text Available Objective: Multicystic dysplastic kidney is a relatively common developmental abnormality in infants and children. Additional abnormalities like vesicoureteral reflux, ureteropelvic junction obstruction, and ureterovesical junction obstruction may accompany multicystic dysplastic kidney. In this article, we reviewed the pathogenesis, diagnosis, associated urinary tract anomalies and results of management of multicystic dysplastic kidney in the light of the literature.Material and Method: We retrospectively assessed 20 children with unilateral multicystic dysplastic kidney between January 2005 and December 2009. Mean duration of follow-up was 35 ± 8.7 months. All children with multicystic dysplastic kidney underwent nephrectomy. Patient characteristics, the pathology findings, associated urinary tract anomalies and results of management were reviewed.Results: Abdominal ultrasound, voiding cystourethrography and renal scintigraphy revealed vesicoureteral reflux in 3 (15% children, ureteropelvic junction obstruction in 3 (15% children, and a duplex system in the contralateral kidney in 1 (5% child. Blood pressure values, serum urea, creatinine and urinalysis were within normal range in all children during follow-up.Conclusion: A conservative approach to children with multicystic dysplastic kidney has been advocated, but surgical removal is also another management modality on the basis of risk of hypertension, mass effect, potential for malignant change, and cost of repeated ultrasound examination.

  11. The state repatriation programme: four years later

    Directory of Open Access Journals (Sweden)

    Kirillova Yelena

    2010-12-01

    Full Text Available This article analyses the problems of the state voluntary repatriation programme and describes its key functions and implementation mechanisms. The author identifies the causes of deceleration in the repatriation process as well as the weak points of the Programme and the ways to improve it. The article offers data on the resettlement of compatriots over the three years of the Programme implementation, its demographic structure, and the regions of resettlement.

  12. Teaching Styles in Four-Year-Olds.

    Science.gov (United States)

    Feshbach, Norma D.; Devor, Geraldine

    1969-01-01

    This study investigates the relationship between social-class factors and patterns of reinforcement used by preschool children when instructing younger peers. It was hypothesized that middle class Caucasian children would spontaneously use more positive reinforcements and lower class children more negative reinforcements when interacting with…

  13. Philadelphia's Renaissance Schools Initiative after Four Years

    Science.gov (United States)

    Stratos, Kati; Wolford, Tonya; Reitano, Adrienne

    2015-01-01

    In 2010-2011, the School District of Philadelphia (the District) launched its Renaissance Schools Initiative, a program designed to dramatically improve student achievement in the District's lowest performing schools. Some schools became Promise Academies, based on the federal turnaround model, and remained District-operated neighborhood schools.…

  14. Adolescent Literature Revisited after Four Years.

    Science.gov (United States)

    Donelson, Ken, Ed.

    1976-01-01

    The articles collected in this bulletin survey a wide range of topics concerning adolescent literature. Some of the titles included are "Seven Myths about Adolescent Literature" (Paul B. Janeczko), "The Book as Enemy" (Thomas Weaver), "Popular Non-Fiction Titles for Adolescents" (Noma Russell), "Values and Paperback Power" (Nel Ward), "An Approach…

  15. Lifestyle and health status in a sample of Swedish women four years after pregnancy: a comparison of women with a history of normal pregnancy and women with a history of gestational diabetes mellitus.

    Science.gov (United States)

    Persson, Margareta; Winkvist, Anna; Mogren, Ingrid

    2015-03-13

    Despite the recommendations to continue the regime of healthy food and physical activity (PA) postpartum for women with previous gestational diabetes mellitus (GDM), the scientific evidence reveals that these recommendations may not be complied to. This study compared lifestyle and health status in women whose pregnancy was complicated by GDM with women who had a normal pregnancy and delivery. The inclusion criteria were women with GDM (ICD-10: O24.4 A and O24.4B) and women with uncomplicated pregnancy and delivery in 2005 (ICD-10: O80.0). A random sample of women fulfilling the criteria (n = 882) were identified from the Swedish Medical Birth Register. A questionnaire was sent by mail to eligible women approximately four years after the pregnancy. A total of 444 women (50.8%) agreed to participate, 111 diagnosed with GDM in their pregnancy and 333 with normal pregnancy/delivery. Women with previous GDM were significantly older, reported higher body weight and less PA before the index pregnancy. No major differences between the groups were noticed regarding lifestyle at the follow-up. Overall, few participants fulfilled the national recommendations of PA and diet. At the follow-up, 19 participants had developed diabetes, all with previous GDM. Women with previous GDM reported significantly poorer self-rated health (SRH), higher level of sick-leave and more often using medication on regular basis. However, a history of GDM or having overt diabetes mellitus showed no association with poorer SRH in the multivariate analysis. Irregular eating habits, no regular PA, overweight/obesity, and regular use of medication were associated with poorer SRH in all participants. Suboptimal levels of PA, and fruit and vegetable consumption were found in a sample of women with a history of GDM as well as for women with normal pregnancy approximately four years after index pregnancy. Women with previous GDM seem to increase their PA after childbirth, but still they perform their PA at

  16. A four-year follow-up study of attention deficit hyperactivity symptoms, comorbidities and psychostimulant use in a brazilian sample of children and adolescents with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Sônia M M Palma

    2015-10-01

    Full Text Available The aim of this study was to evaluate symptom persistence in attention-deficit/hyperactivity disorder (ADHD, the development of comorbidities, and psycho-stimulant usage patterns. Follow-up studies were conducted in 37 patients with ADHD and 22 healthy controls, aged 10 and 18, four years after their first assessment. The ADHD was rated as persistent if participants met all DSM IV criteria for syndromic or sub-threshold persistence, or had functional impairments (functional persistence. Of the 37 ADHD patients we reevaluated, 75% had persistent symptoms, and psychiatric comorbidities with additional functional impairments and academic problems were more common than in controls. These follow-up findings show a high comorbidity associated with ADHD and support the importance of evaluation and treatment for ADHD and comorbidities throughout life.

  17. Reduced Cardiovascular Mortality 10 Years after Supplementation with Selenium and Coenzyme Q10 for Four Years: Follow-Up Results of a Prospective Randomized Double-Blind Placebo-Controlled Trial in Elderly Citizens.

    Directory of Open Access Journals (Sweden)

    Urban Alehagen

    Full Text Available Selenium and coenzyme Q10 are important antioxidants in the body. As the intake of selenium is low in Europe, and the endogenous production of coenzyme Q10 decreases as age increases, an intervention trial using selenium and coenzyme Q10 for four years was performed. As previously reported, the intervention was accompanied by reduced cardiovascular mortality. The objective of the present study was to analyze cardiovascular mortality for up to 10 years after intervention, to evaluate if mortality differed in subgroups differentiated by gender, diabetes, ischemic heart disease (IHD, and functional class.Four-hundred forty-three healthy elderly individuals were included from a rural municipality in Sweden. All cardiovascular mortality was registered, and no participant was lost to the follow-up. Based on death certificates and autopsy results mortality was registered.Significantly reduced cardiovascular mortality could be seen in those on selenium and coenzyme Q10 intervention. A multivariate Cox regression analysis demonstrated a reduced cardiovascular mortality risk in the active treatment group (HR: 0.51; 95%CI 0.36-0.74; P = 0.0003. The reduced mortality could be seen to persist during the 10-year period. Subgroup analysis showed positive effects in both genders. An equally positive risk reduction could be seen in those with ischemic heart disease (HR: 0.51; 95%CI 0.27-0.97; P = 0.04, but also in the different functional classes.In a 10-year follow-up of a group of healthy elderly participants given four years of intervention with selenium and coenzyme Q10, significantly reduced cardiovascular mortality was observed. The protective action was not confined to the intervention period, but persisted during the follow-up period. The mechanism explaining the persistency remains to be elucidated. Since this was a small study, the observations should be regarded as hypothesis-generating.

  18. Four Years Prospective Study of Natural History of Atopic Dermatitis Aged 7~8 Years at an Individual Level: A Community-Based Survey by Dermatologists' Skin Examination in Childhood

    Science.gov (United States)

    Kim, Young Jee; Yun, Sook Jung; Lee, Jee-Bum; Kim, Seong Jin; Won, Young Ho

    2016-01-01

    Background The age-dependent change in atopic dermatitis (AD) at an individual level has mostly performed in a hospital-setting. Objective We evaluated the age-dependent change of AD symptoms at an individual level in a community-setting. Methods For the diagnostic accuracy, all participants of schoolchildren were received skin examination by dermatologists (twice a year for the same group), instead of questionnaire-based surveys. For this study, sequential check-ups of 273 elementary school children, aged 7~8 years, were performed for 4 years up to the age of 10~11 years. Results Among the 47 AD children, who had been diagnosed as having AD at the first-year check-up, spontaneous remission was detected in nine children during the follow-up periods (remission rate of 19.1%). As a consequence, the one-year AD prevalence was decreased by 5.9% in the elementary schoolchildren over four years. Unexpectedly, late onset (after 8 years of age) AD was observed in 21.7% of AD children. There was no statistically significant relationship between spontaneous remission and host factors including sex and family history of atopic diseases. Conclusion We observed that 19.1% of AD children in the age group of 7~11 years showed spontaneous remission based on skin examination by dermatologists. There might be an increase in the prevalence of late onset AD in Korea. PMID:27904266

  19. Accelerated increase and decrease in subjective age as a function of changes in loneliness and objective social indicators over a four-year period: results from the health and retirement study.

    Science.gov (United States)

    Ayalon, Liat; Palgi, Yuval; Avidor, Sharon; Bodner, Ehud

    2016-07-01

    The study examined the role of changes in loneliness and objective social indicators in the formation of changes in subjective age over a four-year period. The Health and Retirement Study is a US nationally representative study of older adults over 50 and their spouse of any age. We restricted the sample to individuals, 65 years of age and older (n = 2591). An accelerated increase in subjective age was defined as an increase in subjective age over the two waves greater than five years. An accelerated decrease in subjective age was defined as a difference that was lower than three years. These were examined against a change in subjective age in the range of three to five years (i.e., change consistent with the passage of time). For 23.4% of the sample, changes in subjective age were consistent with the passage of time. A total of 38.3% had an accelerated decrease in subjective age, whereas 38.3% had an accelerated increase. A decrease in loneliness over the two waves resulted in an accelerated decrease in subjective age, whereas an increase in depressive symptoms resulted in an accelerated increase in subjective age. Changes in objective social indicators, physical difficulties or medical comorbidity did not predict changes in subjective age. This is one of very few studies that examined changes in subjective age over time. Changes in subjective age represent an important construct that corresponding to other changes in subjective experiences.

  20. Identification of potentially emerging food safety issues by analysis of reports published by the European Community's Rapid Alert System for Food and Feed (RASFF) during a four-year period.

    Science.gov (United States)

    Kleter, G A; Prandini, A; Filippi, L; Marvin, H J P

    2009-05-01

    The SAFE FOODS project undertakes to design a new approach towards the early identification of emerging food safety hazards. This study explored the utility of notifications filed through RASFF, the European Commission's Rapid Alert System for Food and Feed, to identify emerging trends in food safety issues. RASFF information and alert notifications published in the four-year period of July 2003-June 2007 were assigned to categories of products and hazards. For chronological trend analysis, a basic time unit of three months was chosen. Data within each hazard category were analyzed for chronological trends, relationships between product and hazard categories, regions of origin, and countries filing the notifications. Conspicuous trends that were observed included a rise in the incidence of food contact substances, particularly 2-isopropyl-thioxanthone, as well as of chemical substances migrating from utensils and fraud-related issues. Temporary increases were noted in the incidences of the unauthorized dye Para Red, genetically modified organisms, the pesticide isophenfos-methyl, and herring worm, Anisakis simplex. National and European authorities themselves have signaled these conspicuous trends and taken measures. It is recommended to add complementary data to RASFF data, including safety assessments, risk management measures, background data on hazards and surveillance patterns, for a holistic approach towards early identification of emerging hazards.

  1. [Efficacy studies].

    Science.gov (United States)

    Pedro-Botet, Juan; Flores-Le Roux, Juana A

    2014-07-01

    Pravafenix(®) is a fixed-dose combination of 40mg of pravastatin and 160 mg of fenofibrate. The rationale behind the use of Pravafenix(®) is based on the increased residual cardiovascular risk observed in high risk patients with hypertriglyceridemia and/or low HDL cholesterol levels despite treatment with statins in monotherapy. In this article, we review the available evidence on the clinical efficacy of Pravafenix(®), which shows complementary benefits in the overall lipid profile of high risk patients with mixed dyslipidemia not controlled with 40-mg pravastatin or 20-mg simvastatin. Copyright © 2014 Sociedad Española de Arteriosclerosis y Elsevier España, S.L. All rights reserved.

  2. Impact of New Shift Models for Doctors Working at a German University Hospital for Gynaecology and Obstetrics Four Years After Implementation. Can They Meet the European Working Time Directive Without Increasing Costs?

    Science.gov (United States)

    Maschmann, J; Holderried, M; Blumenstock, G; Bamberg, M; Rieger, M A; Wallwiener, D; Brucker, S

    2013-07-01

    Background: The impact of the European Working Time Directive and subsequent collective wage agreements for doctors from 2006 onwards were substantial. So far, no systematic evaluation of their application in Germany has been performed. We evaluated the impact four years after implementation of new shift models in a University Hospital for Gynaecology and Obstetrics (UHGO). Methods: A new shift model was created together with doctors of Tübingen UHOG in 2007 and implemented in 2008. Documentation of working hours has hence been done electronically. Adherence to the average weekly working time limit (AWTL) and the maximum of 10 h daily working time (10 h-dwt) was evaluated, as well as staffing costs in relation to case-weight points gathered within the German DRG (diagnosis related groups) System. Results: Staff increased from a mean of 44.7 full time equivalent (FTE) doctors in 2007 to 52.5 FTE in 2009, 50.8 in 2010, and 54.5 in 2011. There was no statistically significant difference of the monthly staff expenditures per case-weight between the years 2009 or 2010 vs. 2007. 2011, however, was significantly more expensive than 2007 (p = 0.02). The internal control group (five other departments of the university hospital) did not show an increase during the same period. AWTL were respected by 90, 96, and 98 % in 2009, 2010, and 2011, respectively. Of all shifts 10 h-dwt was exceeded by 7.4 % in 2009, 1.3 % in 2010, and 2.6 % in 2011, with significant differences between 2009 and both, 2010 and 2011 (p implementation of the new shift model without increasing the cost/earnings ratio for the first two years. However, in 2011 the ratio increased significantly (p = 0.02).

  3. Conservative treatment with spontaneous stabilization of Grade II isthmic spondylolisthesis L5/S1 in a forty-four-year old woman, with a six-year follow-up: a case report.

    Science.gov (United States)

    Ferrari, S; Costa, F; Fornari, M

    2012-06-01

    Spondylolisthesis is a pathological condition caused by the slipping of a vertebral body, compared to the underlying structure, following structural and/or degenerative changes to the spine. Studies have attempted evidence to the connection between the natural history of spondylolisthesis, the degree and progression of the slip factor, as well as the pain and disability. Studies have reported a high level of heterogeneity of these factors in different patients as well as difficulty in predicting behaviour. It has been suggested that vertebral instability, independent of the slip factor, could be considered the most important factor to be treated conservatively or surgically. Furthermore, it appears that some patients may manifest complete disk degeneration over time, with vertebral bodies shifting closer and spontaneous stabilisation. This case study reports a forty-four-year old woman, with isthmic spondylolisthesis, where the spine surgeon recommended physiotherapy for conservative treatment, with a prognosis of possible spontaneous stabilization. The case was followed for six years, both clinically and radiologically. Treatment was based on a specific stabilising training program (motor control), immediately aimed to improve the disability and pain factors while waiting for a possible spontaneous stabilisation, that the latest radiological exams revealed with an attempt of arthrodesis. The Oswestry Disability Index (ODI) and the Roland Morris Disability Questionnaire (RMDQ) to measure disability, and the Numeric Rating Scale (NRS) to measure pain, were carried out at the beginning, during and at the end of treatment. They were compared with the radiographic material documenting the evolution of the spondylolisthesis over time. This case study appears to confirm that the hypothesis that a specific aimed approach of rehabilitation may improve the disability and pain levels without compromising the process of spontaneous arthrodesis. The evolution was documented

  4. Effects of hormones on skin wrinkles and rigidity vary by race/ethnicity: four-year follow-up from the ancillary skin study of the Kronos Early Estrogen Prevention Study.

    Science.gov (United States)

    Owen, Carter M; Pal, Lubna; Mumford, Sunni L; Freeman, Ruth; Isaac, Barbara; McDonald, Linda; Santoro, Nanette; Taylor, Hugh S; Wolff, Erin F

    2016-10-01

    To measure skin wrinkles and rigidity in menopausal women of varying race/ethnicity with or without hormone therapy (HT) for up to four years. Randomized, double-blind, placebo-controlled trial. Academic medical centers. Women (42-58 years of age) within 36 months of last menstrual period and enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). Treatment with 0.45 mg oral conjugated equine estrogens (CEE), transdermal E2 (50 μg/d) with micronized P (200 mg daily), or placebo for 4 years. Skin wrinkles were assessed at 11 locations on the face and neck, and skin rigidity was assessed at the forehead and cheek at baseline and yearly for 4 years. Neither total wrinkle score nor total rigidity score was significantly different at baseline or over the 4-year follow-up among patients randomized to CEE, E2, or placebo. Skin wrinkle and rigidity scores were primarily affected by race/ethnicity, with scores being significantly different between races for almost all of the wrinkle parameters and for all of the rigidity measures. There was no association between race and response to HT for total wrinkle or rigidity scores. Black women had the lowest wrinkle scores compared with white women across all 4 years. In general, skin rigidity decreased in all groups over time, but black women had significantly reduced total facial rigidity compared with white women after 4 years. Race is the strongest predictor of the advancement of skin aging in the 4 years following menopause. HT does not appear to affect skin wrinkles or rigidity at most facial locations. NCT00154180. Published by Elsevier Inc.

  5. Applying Self-Efficacy Theory to Understanding the Behavioral Expectations of College Students with Disabilities in Requesting Accommodations

    Science.gov (United States)

    Snitker-Magin, Mikael C.

    2010-01-01

    The purpose of the study was to apply Bandura's self-efficacy theory to understanding the behavior of college students with disabilities in requesting accommodations. Students with disabilities were recruited from 20 two-year and four-year postsecondary institutions by asking student disabilities services staff to forward an email invitation to…

  6. A four-year monitoring of community-acquired Streptococcus agalactiae infection in urogenital tract%社区获得性泌尿生殖道无乳链球菌感染4年监测

    Institute of Scientific and Technical Information of China (English)

    李国钢; 周杨霄; 李佳俊; 方美芳; 万汝根

    2012-01-01

    OBJECTIVE To understand the status of the community-acquired Streptococcus agalactiae infection of urogenital tract and drug resistance for the rational use of antibiotics. METHODS A retrospective analysis and statistics were performed for the S. Agalactiae isolated from the genitourinary tract specimens of outpatient in our hospital from Jan 2007 to Dec 2010. RESULTS The resistance rates of S. Agalactiae to erythromycin and clindamycin showed an increasing trend year by years the resistance rates to the tetracycline and levofloxacin had no significant difference among four years; the resistance rate to penicillin was less than 10. 0% ; The resistance to vancomycin and linezolid had not be found. The positive rate of D-test was 28. 6%. CONCLUSION Use of macrolides and clindamycin should be minimized in the treatment of S. Agalactiae infection. Penicillin antibiotics can not be used in preventive and empirical therapy. Clinicians should have a reasonable choice in antibiotics based on the susceptibility results.%目的 了解社区获得性泌尿生殖道无乳链球菌感染现状及耐药性分析,以指导临床合理用药.方法 对2007年1月-2010年12月送检的泌尿生殖道标本所分离的无乳链球菌,进行回顾性分析.结果 红霉素、克林霉素对无乳链球菌的耐药率呈逐年上升趋势,且增长速度很快;四环素与左氧氟沙星的耐药率4年间无明显差异;青霉素耐药率均<10.0%;万古霉素及利奈唑胺未发现耐药;D试验阳性率为28.6%.结论 在诊治无乳链球菌感染的过程中,应尽量减少大环内酯类药物及克林霉素的使用,青霉素类抗菌药物已不能作为预防和经验治疗用药,临床医师应根据药敏结果合理选择抗菌药物.

  7. Rotação de culturas para trigo, após quatro anos: efeitos na fertilidade do solo em plantio direto Crop rotation systems for wheat, after four years: effects on soil fertility under no-tillage

    Directory of Open Access Journals (Sweden)

    Henrique Pereira dos Santos

    1999-06-01

    Full Text Available A fertilidade do solo foi avaliada, após quatro anos (1990 a 1994, num latossolo bruno álico, em Guarapuava, PR, Brasil, em quatro sistemas de rotação de culturas para trigo: sistema I (trigo/soja; sistema II (trigo/soja e aveia branca/soja; sistema III (trigo/soja, ervilhaca/ milho e aveia branca/soja; e sistema IV (trigo/soja, aveia branca/soja, cevada/soja e ervilhaca/ milho. As culturas, tanto de inverno como de verão, foram estabelecidas sob plantio direto. O delineamento experimental foi de blocos ao acaso com quatro repetições. Através de contrastes, foram comparados os sistemas e as profundidades de amostragem de solo. Em todos os sistemas de rotação de culturas, na camada de solo 0 a 5cm, observaram-se valores maiores de pH e de Ca+Mg e menores de Al (com exceção do sistema III, em relação à camada 15 a 20cm. Houve elevação dos teores de Ca+Mg, de K e de P na camada de solo com a maior concentração de raízes (0 a 10cm. Os valores de matéria orgânica do solo decresceram progressivamente da camada 0 a 5cm para a camada 15 a 20cm.Soil fertility parameters were evaluated after four years (1990 to 1994 on a alic dusky latosol located in Guarapuava, Paraná, Brazil, under four wheat crop rotation systems as follows: system I (wheat/soybean; system II (wheat/soybean and white oats/soybean; system III (wheat/soybean, common vetch/corn, and white oats/soybean; and system IV (wheat/soybean, white oats/soybean, barley/soybean and common vetch/cor. Both winter and summer crops were seeded under no tillage. A randomized complete block design, with four replications, was used. Crop systems and soil samples at different depths were compared using the contrast procedure. All crop rotation systems, in the 0 to 5cm soil layer, higher values were observed for pH in water and Ca+Mg and lower contents for Al (except system III, as compared to the 15 to 20cm layer. Raising in Ca+Mg, K, and P levels occurred in the soil layer with the

  8. Variations analysis on the four years growth characters of half-sibs family of Pinus takahasii Nakai%兴凯湖松半同胞家系4年生长性状变异分析

    Institute of Scientific and Technical Information of China (English)

    兰士波

    2012-01-01

    为探索兴凯湖松半同胞家系的生长动态规律,以迁地保存林为对象,通过连续4年的观测,比较分析了树高和年生长量2个数量性状的遗传变异.并根据方差分析的结果,估算出家系遗传力、遗传增益和遗传变异系数等遗传参数,在此基础上对入选家系进行综合评价.结果表明:在苗木培育期,兴凯湖松半同胞家系的生长节律与樟子松基本趋于一致,且群体内立地类型间苗高性状存在丰富的变异,变异幅度为30.35%~35.15%.子代测定林的树高和年生长量在鸡西群体内立地类型间差异极显著,变异主要源自基因型间的差异,家系遗传力(0.3900、0.308 6)中等,选择增益(5.19%、5.69%)较大;在早期选择评价时,以生长量为目的性状,经遗传增益估算和选择评价,确定JX06、JX14和JX01为高寒地区引种栽培的适宜品种,且品种内家系间的数量性状变异较小,生长稳定,具广泛推广应用的价值.%In order to probe the dynamic growth rhythm of half-sibs family\\of Pinus takahasii Nakai, eight-year-old ex-situ conservation forest was used as material in this paper. Through four years continuous measuring, genetic variation of two quantitative characters, height and annual growth increment were selected for analysing. And their heritability, genetic gain and genetic variation were estimated. The results showed that there were abundant variations in height character between forest site types and within populations, and the coefficient of variation was from 30. 35% to 35. 15% , and its growth rhythm was similar to Pinus sylvestris var. mongolica. However, significant differences consisted in two quantitative characters between forest site types and within Jixi population. The heritability of its height and annual growth increments were 0. 390 0 and 0. 308 6 respectively. Its genetic gain were 5. 19% and 5. 69%. It was found that three families of JX06, JX14 and JX01 grew well and the

  9. Four-year clinical observation of Magfit magnetic attachment in mandibular complete overdentures%Magfit磁性附着体在下颌全口覆盖义齿修复中的4年临床观察

    Institute of Scientific and Technical Information of China (English)

    唐丽琴; 刘凤玲; 吴悦梅; 陈键

    2012-01-01

    目的 研究Magfit磁性附着体在下颌全口覆盖义齿中的临床修复效果.方法 对2008年8月-2011年8在无锡口腔医院修复科就诊的16例符合条件的患者,分别选择1~2个基牙放置磁性附着体制作全口覆盖义齿.在修复后1个月、3个月、6个月、1年、2年、3年及至今分别进行回访复查,以问卷形式调查分析患者对修复效果的满意度,主要观察义齿的固位、稳定性,固位体周围牙龈的健康状况,基牙松动度、继发龋.结果 患者对磁性附着体义齿修复的舒适性和咀嚼效率满意度最高,固位和稳定性、语音功能次之,费用满意度最低.3例基牙出现牙龈炎,2颗基牙出现松动,1个磁体脱落,2例折裂,其余良好.结论 采用磁性附着体的下颌全口覆盖义齿可以提高义齿的舒适性和稳定性,增加患者的满意度.%Objective To study clinical restoration effects of Magfit magnetic attachment in mandihular complete overdentures. Methods Sixteen eligible subjects were selected who visited Department of Prosthodontics in Wuxi Stomatology Hospital from August, 2008 to August ,2011. One or two abutments were selected to put magnetic attachment so as to take on complete overdentures. Follow-ups were done one month,three months,six months,one year,two years,three years and four years after restoration. Patients' satisfaction of restoration was surveyed by questionnaires. The retention and stability of denture, gingival health around the retainers, mobility and secondary caries of abutments were the main observed aspects. Results The patients with magnetic attachment in complete overdentures claimed a highest grade of satisfaction in comfort and masticatory performance, a higher grade of satisfaction in retention, stability and phonetic function and a lowest grade of satisfaction in costs. Three abutment teeth had gingivitis ,two abutment teeth were mobile,one magnet retainer dropped,and two fractured. The rest were good

  10. Evolução clínica e capacidade funcional de pacientes com cardiomiopatia dilatada após quatro anos do transplante Clinical and functional capacity of patients with dilated cardiomyopathy after four years of transplantation

    Directory of Open Access Journals (Sweden)

    Daniela Gardano Bucharles Mont'Alverne

    2012-12-01

    Full Text Available OBJETIVO: Avaliar a evolução do paciente miocardiopata após transplante (Tx cardíaco, analisando sua sobrevida, complicações trans e pós-operatórias e respostas cardiovasculares após cerca de quatro anos do procedimento cirúrgico. MÉTODOS: A pesquisa foi realizada no período de fevereiro a maio de 2011, com pacientes submetidos a Tx cardíaco no Hospital Dr. Carlos Alberto Studart Gomes - Hospital de Messejana (HDM. A amostra foi composta de todos os pacientes transplantados no ano de 2007 no referido hospital. Inicialmente, foi aplicada uma ficha de avaliação, coletando dados dos prontuários, sobre a evolução do paciente no período trans e pós-operatório até a alta hospitalar. Após a coleta dessas informações, os pacientes foram submetidos ao teste da caminhada dos seis minutos (TC6. Os valores encontrados na distância percorrida foram comparados aos valores de referência esperados para a população utilizando a equação de Enright e Sherrill. RESULTADOS: Do total de 24 pacientes que realizaram Tx cardíaco no HDM no ano de 2007, 14 foram avaliados e 10 excluídos do estudo. Com relação às complicações, no período transoperatório, a mais evidenciada foi a disfunção do ventrículo direito (64,3% e, no pós-operatório, quadro de taquicardia (64,3%. Analisando o TC6 observou-se diminuição de 11,6% na distância percorrida quando comparada à distância estimada (486 ± 55 m, 550 ± 59 m, respectivamente. CONCLUSÃO: Os resultados obtidos neste estudo perante o TC6 evidenciam que as respostas cardiovasculares dos pacientes avaliados estão abaixo do estimado, contudo dentro da faixa de normalidade estabelecida.OBJECTIVE: To evaluate patient with cardiomyopathy's progress after cardiac transplant, by analyzing his survival, complications and cardiovascular responses after nearly four years of surgery. METHODS: The survey was conducted from February to May 2011, with patients undergoing cardiac transplantation

  11. An Exploratory Study into the Efficacy of Learning Objects

    Directory of Open Access Journals (Sweden)

    Nicholas W. Farha

    2009-07-01

    Full Text Available Learning objects have quickly become a widely accepted approach to instructional technology, particularly in on-line and computer-based learning environments. While there is a substantial body of literature concerning learning objects, very little of it verifies their efficacy. This research investigated the effectiveness of learning objects by comparing learning outcomes using a learning object with outcomes using a traditional textbook-based method of instruction. Participants were 327 undergraduate college students at a traditional public four-year coed institution, a private four-year women’s college, a private four-year engineering institution, and a public two-year community college. Through a series of independent samples t-tests and Analyses of Variance, results revealed mean scores for the learning object group that were nearly three times higher than the mean scores for the textbook-taught group. Gaming experience, age, gender, and learner preference were evaluated for their potential influence on the results; no statistically significant differences were found, implying that the learning object itself was central to the outcomes achieved. The future of learning objects is bright, and more empirical research is called for in the area of learning object effectiveness.

  12. Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, Mary Ann; Johnson, Robert L.; McKinstry, Craig A.; Simmons, Carver S.; Cook, Chris B.; Brown, Richard S.; Tano, Daniel K.; Thorsten, Susan L.; Faber, Derrek M.; Lecaire, Richard; Francis, Stephen

    2004-01-01

    This report documents the third year of a four-year study to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee salmon (Oncorhynchus nerka) and rainbow trout (O. mykiss) in the forebay to the third powerplant at Grand Coulee Dam. This work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes).

  13. Das interaktive Chirurgische Logbuch im Praktischen Jahr: Eine mehrjährige Retrospektive [Interactive Logbook in the Surgical Training of Final Year Medical Students: A Four-Year Retrospective

    Directory of Open Access Journals (Sweden)

    Kadmon, Guni

    2009-05-01

    Full Text Available [english] Aims: An interactive surgical logbook was introduced in 2004 as part of a reform of the 16-week surgical training period of the final medical year at Heidelberg University. The present work describes its aims and development and examines its utilization by students and supervising doctors over a period of four years. Methods: The surgical training period of the final medical year was evaluated in 2003 by means of questionnaires and interviews with doctors, nurses, orderlies, and final-year medical students. Subsequently, a catalog of training objectives was compiled, which formed the basis for a logbook that states the training objectives, outlines the curriculum of the surgical training period, and includes separate pages for documenting 31 different medical procedures including the treatment of three patients under one’s care. It further includes tables for recording one’s attendance at training activities and detachable forms for self-assessment, evaluation of the surgical training period, and assessment of the student by the training doctors. The logbook was given to all students in their final-year surgical training period, but its use was optional. The entries in all returned logbooks were retrieved, recorded, and analyzed. Results: The return rate of the logbooks was initially low but rose within two years to 80%–100%. The extent of the entries was, however, continuously poor. Nineteen percent of the logbooks were devoid of entries, approximately 40% had no entries of clinical procedures, and the majority of the rest contained very incomplete records. The extent of feedback and comments by the supervising doctors was very limited, and their assessment forms often were filled in by the students themselves. By contrast, students returned numerous self-assessment and evaluation questionnaires that were complete and contained differentiated entries. Informal interviews with students revealed that cooperation was lacking on the

  14. Long term outcomes of three-four-year-old offsprings of mothers with gestational diabetes mellitus%妊娠期糖尿病患者子代3~4岁的随访研究

    Institute of Scientific and Technical Information of China (English)

    宋耕; 孔令英; 王晶; 宋依临; 杨慧霞

    2013-01-01

    group [weight (17.2±2.5) kg,BMI (16.2± 1.4),waist circumference (50.5 ± 3.6) cm,DBP (55.2 ± 6.9)mm Hg,SSF(6.1 ± 1.8) mm,WHZ (0.62±0.87),HAZ (0.53±0.99),WAZ (0.73±0.92),BAZ(0.61±0.89)],the weight (F=9.283,P<0.001),BMI (F=8.707,P<0.001),waist circumference (F=7.934,P<0.001),DBP(F=3.123,P=0.046),SSF (F=3.499,P=0.032),WHZ (F=7.639,P<0.001),HAZ(F=4.709,P=0.010),WAZ (F=10.302,P<0.001) and BAZ (F=7.689,P<0.001) was higher in GDM group than the control group.(4) The proportions of overweight and obesity were higher in GDM macrosomia subgroup than in GDM non-macrosomia and control groups [overweight:9/15 vs24.8% (27/109) and 24.5% (24/98),x2 =8.870,P=0.012; obesity:5/15 vs 7.3%(8/109) and 9.2%(9/98),x2=10.083,P=0.006].If all subjects were divided into macrosomia and non-macrosomia group,then the proportion of overweight and obesity was higher in the former group [overweight:52.4% (11/21) vs24.4%(49/201),x2=7.560,P=0.006; obesity:28.6% (6/21)vs 7.9%(16/201),x2 =9.047,P=0.003].Conclusions GDM may have long term adverse effect on the development of offsprings at three-four-year-old with higher incidence of obesity or high diastolic blood pressure in macrosomic babies of GDM mothers than in non macrosomic babies of GDM mothers or babies of non GDM mothers.

  15. Self-Efficacy and Computers.

    Science.gov (United States)

    Olivier, Terry A.; Shapiro, Faye

    1993-01-01

    Presents a conceptual analysis of self-efficacy and reviews the literature on self-efficacy in the microcomputer environment. Topics addressed include self-efficacy versus other theories; efficacy versus outcome expectations; and sources of efficacy information, including performance accomplishments, vicarious experiences, verbal persuasion, and…

  16. Four years' cytogenetic experience with the culture of chorionic villi

    NARCIS (Netherlands)

    Sikkema-Raddatz, B; Bouman, K; Verschuuren-Bemelmans, CC; Stoepker, M; Mantingh, A; Beekhuis, [No Value; de Jong, B

    2000-01-01

    In 1958 chorionic villus samples, investigated by culture method, we found 137 (7%) abnormalities. The abnormal results were classified in certain abnormal (generalised abnormal at high probability) and uncertain abnormal (potentially confined to the placenta) results. Certain abnormal were 73 cases

  17. A survey of four years intrauterine insemination at Shariati Hospital

    Directory of Open Access Journals (Sweden)

    Aghahosseini M

    1998-08-01

    Full Text Available Intrauterine insemination (IUI has been practiced since the late 1800's primarily for idiopathic infertility, and in men with deficient semen parameters. The procedure is done by placing washed sperm in uterus a few hours before ovulation. The records of 427 couples receiving IUI for treatment of infertility at Shariati hospital in 1370-74 were reviewed retrospectively. These patients had IUI in 574 cycles. Eighty patients became pregnant and delivery rate was 14% per cycle. Pregnancy rate is impressive when ovulation induction is combined with insemination timed just before ovulation. The success rate in Shariati hospital is comparable to other infertility centers in the world and cost of a cycle of IUI with HMG superovulation is approximately one third the cost of IVF-ET or GIFT cycle and avoids invasive oocyte retrieval and extracorporeal fertilization. So we suggest that women with refractory infertility without anatomic distortion of pelvis can have at least 3-6 cycles of IUI before IVF or GIFT.

  18. Four years on: Are the gazelles still running?

    DEFF Research Database (Denmark)

    Senderovitz, Martin; Klyver, Kim; Steffens, Paul

    2016-01-01

    –profitability relationship and are tested using longitudinal data from a sample of 964 Danish gazelle firms. We find a positive relationship between growth and profitability among gazelle firms. This relationship is moderated, however, by market strategy; it is stronger for firms pursuing a broad market strategy rather than...

  19. The War Powers Resolution: After Thirty-Four Years

    Science.gov (United States)

    2008-03-10

    Sidra . In response, the United States fired missiles at Libyan vessels and at Sirte, the Libyan missile site involved. The U.S. presence in the Gulf of... Sidra , an area claimed by Libya, was justified as an exercise to maintain freedom of the seas, but it was widely considered a response to terrorist...report on the bombing did not cite section 4(a)(1) and the Gulf of Sidra report did not mention the War Powers Resolution at all. Since the actions

  20. Testing some common tennis hypotheses: Four years at Wimbledon

    NARCIS (Netherlands)

    Magnus, J.R.; Klaassen, F.J.G.M.

    1996-01-01

    In this paper we investigate the truth (more often the untruth) of seventeen commonly heard statements about tennis. We base our analysis on point-by-point data of almost 500 singles matches played at Wimbledon, 1992-1995. The seventeen hypotheses under consideration are: 1 A player is as good as

  1. Testing some common tennis hypotheses : Four years at Wimbledon

    NARCIS (Netherlands)

    Magnus, J.R.; Klaassen, F.J.G.M.

    1996-01-01

    In this paper we investigate the truth (more often the untruth) of seventeen commonly heard statements about tennis.We base our analysis on point-by-point data of almost 500 singles matches played at Wimbledon, 1992-1995.The seventeen hypotheses under consideration are: 1 A player is as good as

  2. Gastric necrosis four years after fundoplication causing a dead foetus

    DEFF Research Database (Denmark)

    Thinggaard, Ebbe; Skovsen, Anders Peter; Kildsig, Jeppe

    2014-01-01

    A 31-year-old pregnant woman was admitted and treated for diabetic ketoacidosis. As the patient deteriorated and the viability of the foetus was uncertain a CT scan was done which showed free fluid and air intraabdominally. Surgery was performed. A dead foetus was delivered and a 2 × 5 cm necrotic...

  3. Progressive numbness and weakness of extremities for four years

    Directory of Open Access Journals (Sweden)

    Yin-yan XU

    2017-01-01

    Full Text Available Hereditary motor and sensory neuropathy (HMSN, also known as Charcot-Marie-Tooth (CMT, is a hereditary peripheral neuropathy characterized by progressive numbness and weakness of the extremities, atrophy and paresthesia, with genetic mutations in various associated genes such as PMP22, in most cases. Most CMT patients suffer from mild to moderate paresthesia, but only 20-30% of them complain of pain in the limbs. Diabetes mellitus also causes abnormal sensation in peripheral nerves and might arouse confusion in the diagnosis of CMT especially in those with comorbidity of diabetes. Here, we present a late onset case of a PMP22 heterozygote complicated with one year of type 2 diabetes mellitus, who has significant tingling in his fingers and toes. We also present a typical neural ultrasound image of a diffusedly thickened nerve of this patient in support of the diagnosis of CMT1. DOI: 10.3969/j.issn.1672-6731.2017.01.014

  4. Yunnan Launches Four Year Mine Searching Action Plan

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The Yunnan Provincial State Land Resource Bureau has organized the provincial Geological Investigation Bureau and relevant institutions to kick off the "Yunnan Province 2009-2010 Mine Search Action Plan"

  5. Actuarial Science at One Four-Year Comprehensive University

    Science.gov (United States)

    Charlwood, Kevin E.

    2014-01-01

    Building an Actuarial Science program designated as advanced requires dedicated faculty, support from the administration, and a core group of strong students. Washburn University may serve as a model for those wishing to start or enhance such a program at their institution. We face three main ongoing challenges: first, the hiring and retention of…

  6. Actuarial Science at One Four-Year Comprehensive University

    Science.gov (United States)

    Charlwood, Kevin E.

    2014-01-01

    Building an Actuarial Science program designated as advanced requires dedicated faculty, support from the administration, and a core group of strong students. Washburn University may serve as a model for those wishing to start or enhance such a program at their institution. We face three main ongoing challenges: first, the hiring and retention of…

  7. Four Years of Absolute Gravity in the Taiwan Orogen (AGTO)

    Science.gov (United States)

    Mouyen, Maxime; Masson, Frédéric; Hwang, Cheinway; Cheng, Ching-Chung; Le Moigne, Nicolas; Lee, Chiung-Wu; Kao, Ricky; Hsieh, Nicky

    2010-05-01

    AGTO is a scientific project between Taiwanese and French institutes, which aim is to improve tectonic knowledge of Taiwan primarily using absolute gravity measurements and permanent GPS stations. Both tools are indeed useful to study vertical movements and mass transfers involved in mountain building, a major process in Taiwan located at the convergent margin between Philippine Sea plate and Eurasian plate. This convergence results in two subductions north and south of Taiwan (Ryukyu and Manilla trenches, respectively), while the center is experiencing collision. These processes make Taiwan very active tectonically, as illustrated by numerous large earthquakes and rapid uplift of the Central Range. High slopes of Taiwan mountains and heavy rains brought by typhoons together lead to high landslides and mudflows risks. Practically, absolute gravity measurements have been yearly repeated since 2006 along a transect across south Taiwan, from Penghu to Lutao islands, using FG5 absolute gravimeters. This transect contains ten sites for absolute measurements and has been densified in 2008 by incorporating 45 sites for relative gravity measurements with CG5 gravimeters. The last relative and absolute measurements have been performed in November 2009. Most of the absolute sites have been measured with a good accuracy, about 1 or 2 ?Gal. Only the site located in Tainan University has higher standard deviation, due to the city noise. We note that absolute gravity changes seem to follow a trend in every site. However, straightforward tectonic interpretation of these trends is not valuable as many non-tectonic effects are supposed to change g with time, like groundwater or erosion. Estimating and removing these effects leads to a tectonic gravity signal, which has theoretically two origins : deep mass transfers around the site and vertical movements of the station. The latter can be well constrained by permanent GPS stations located close to the measurement pillar. Deep mass transfers, on the contrary, must be evaluated by modelling. Relative gravity, despite lower accuracy, enable us to cover wider area (about 10 000 km2). Our interest is thus to merge both types of measurements to have a large overview of temporal g changes in the south of Taiwan.

  8. Four-year retrospective look for acute scrotal pathologies

    Science.gov (United States)

    Ayvaz, Olga Devrim; Celayir, Aysenur Cerrah; Moralioglu, Serdar; Bosnali, Oktav; Pektas, Osman Zeki; Pelin, Ahmet Koray; Caman, Sefik

    2015-01-01

    OBJECTIVE: A group of diseases in the scrotum setting forth by the sudden swelling and redness and pain consist of acute scrotal pathologies. The most common causes of acute scrotum in children are epididymitis, epididymo-orchitis, orchitis, testicular torsion, torsion of the appendix testis, incarcerated inguinal hernia and traumatic hydro/hematocele. In this study; we aim to evaulate patients with acute scrotal pathologies who were interned in our department. METHODS: All hospital data of cases who were interned at our deparment due to acute scrotum in between June 2010-June 2014 were evaluated retrospectively. Cases with incarcerated inguinal herni were excluded in this study. RESULTS: In a 4-year-period 114 cases were interned in our department with acute scrotum. Mean age of the patients was 7.6±4.577 years (min: 1m-max: 18yrs). Doppler US was performed in 112 patients to evaluate the blood flow while in 2 patients applied after normal office hours were evaluated without Doppler US and operated under emergency conditions. The patients had received diagnosis of epididymitis/epididymo-orchitis/orchitis (n=83 cases; 72.8%), testicular torsion (n=24; 21.1%), torsion of the appendix testis (n=2; 1.8%) with and traumatic hydrocele/ hematocele (n=5; 4.4%). While detorsion was performed in 18 (75%) cases with testicular torsion and orchiectomy in 6 (25%) cases. Histopathological evaluation of orchiectomy specimens revealed hemorrhagic necrosis and hemorrhagic infarction or ischemic changes. Normal testicular size and vascularity were detected in 11 (61.1%) cases with detorsioned testis as detected by follow-up Doppler US. Late orchiectomy was performed in 7 cases (38.9%) with complete atrophy due to lack of blood supply. CONCLUSION: Although Doppler US is very helpful for differential diagnosis of patients with acute scrotum who applied early period, if Doppler US will lead to a waste of time, direct surgery without delay will reduce the risk of testicular loss. PMID:28058365

  9. NDEA Institute Enrollees: Two and Four Years Later

    Science.gov (United States)

    Gust, Tim

    1970-01-01

    Describes a follow-up study of NDEA Counseling and Guidance Institute participants to obtain information on their professional development, job mobility, and their perceptions of their graduate preparation. (DM)

  10. Teaching Styles of Four Year Olds and Their Mothers.

    Science.gov (United States)

    Feshbach, Norma D.

    The purpose of the present investigation is to assess social class and race differences in the use of reinforcement by mothers and children. The general hypotheses underlying this approach is the expectation of a functional similarity between social class and race effects on the use of reinforcements by mothers and children. The subjects were 109…

  11. Four years with FALCON - an ESTRO educational project

    DEFF Research Database (Denmark)

    Eriksen, Jesper Grau; Salembier, Carl; Rivera, Sofia;

    2014-01-01

    Variability in anatomical contouring is one of the important uncertainties in radiotherapy. FALCON (Fellowship in Anatomic deLineation and CONtouring) is an educational ESTRO (European SocieTy for Radiation and Oncology) project devoted to improve interactive teaching, the homogeneity in contouri...... and to compare individual contours with endorsed guidelines or expert opinions. This report summarizes the experience from the first 4 years using FALCON for educational activities within ESTRO School and presents the perspectives for the future....

  12. Achalasia in a sixty-four-year-old man.

    Science.gov (United States)

    Komisaruk, E A; Seymour, N E

    1998-01-01

    Achalasia is an esophageal motility disorder characterized by increased lower esophageal sphincter pressure and absence of peristalsis in the lower esophagus. Patients typically present with complaints of progressive difficulty swallowing over a period of several years. Diagnosis is confirmed by esophageal manometry. Complications of achalasia include esophagitis, aspiration and possibly an increased risk of esophageal carcinoma. Medical treatment options include pneumatic dilatation, esophageal bougienage, nitrates, calcium channel blockers and botulinum toxin injections. The primary method of surgical treatment is the Heller myotomy, in which longitudinal incisions are made in the muscle fibers of the lower esophageal sphincter to reduce sphincter pressure. Frequently, a fundoplication is performed in addition to the myotomy to decrease the likelihood of development of gastroesophageal reflux. In recent years, the Heller myotomy has been performed both thoracoscopically and laparoscopically. An additional development has been the placement of an endoscope in the esophagus to provide transillumination during surgery; intraoperative endoscopy allows improved assessment of the depth of myotomy incisions and reduces the risk of esophageal perforation. The case report below describes a 64-year-old-man with achalasia who presented with persistent dysphagia despite multiple attempts at medical treatment. A laparoscopic Heller myotomy with Toupet fundoplication was performed with subsequent eradication of symptoms. A discussion of the epidemiology, etiology, clinical presentation, diagnosis and treatment of achalasia follows the case report.

  13. Four- year thyroidectomy procedures: Ligasure Vs. clamp & tie

    Directory of Open Access Journals (Sweden)

    Pazoki AR

    2010-01-01

    Full Text Available "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: The electrothermal bipolar vessel sealing system is an adjunct to the hemostatic technique, which has been successfully used in many abdominal operation, recently made available to thyroid surgery. The purpose of this was compare the outcomes of new hemostatic technique with traditional method of clamp and tie."n"nMethods: In this retrospective cross-sectional study has been done in surgery's wards of Milad & Rasul- Akram hospitals in Tehran, Iran. During three- year period between 2005-2008 all patients with different kind of pathology that need operation were assessed. Time duration of surgery and hospital stay and post surgery complication in two group, ligasure (n=45 and clamp & tie (n=145 were compared with each others."n"nResults: No difference was seen between two groups in time duration of surgery. Significant difference was seen in hospital stay and complications of surgery. Time of operation in Ligasure group was 132/22 minute and in clamp and tie group was 130/10 minute. There was found significant difference in duration of hospital stay and postoperative complication. Hypocalcemia were seen in two and 24 cases in Ligasure and Clamp & Tie group, respectively (p<0.05. Hospital stay was 2.18 versus 2.65 day in ligasure and clamp & tie group, respectively (p=0.005."n"nConclusions: Although Ligasure is easier than clamp & tie for surgeons but no reduction in time duration of surgery was seen in ligasure group. The advantages of this method in this study was reduction of hospital stay and complication

  14. [Malnutrition in patients with cancer; four years experience].

    Science.gov (United States)

    Fernández López, María Teresa; Saenz Fernández, Cecilia Alejandra; de Sás Prada, María Trinidad; Alonso Urrutia, Susana; Bardasco Alonso, María Luisa; Alves Pérez, María Teresa; Rivero Luis, María Teresa; Alvarez Vázquez, Paula; Mato Mato, José Antonio

    2013-01-01

    Objetivo: Analizar la prevalencia y el grado de desnutrición de los pacientes con cáncer remitidos a una consulta específica de Nutrición Oncológica. Material y métodos: Se trata de un estudio transversal, observacional y descriptivo basado en los datos recogidos en la primera consulta de nutrición de todos los pacientes mayores de edad con cáncer evaluados en el período comprendido entre el 1 de marzo de 2008 y el 29 de febrero de 2012. Se incluyeron 997 pacientes, a los que se les realizó la Valoración Global Subjetiva Generada por el Paciente. Resultados: El 69% de los pacientes habían perdido más de un 5% de su peso habitual en los 3 meses previos, siendo esto más frecuente entre los portadores de tumores digestivos. El 81,2% de los pacientes tenían dificultades para alimentarse, el síntoma más frecuente era la anorexia (53,3%) y la mediana de síntomas por paciente 3. La Valoración Global Subjetiva Generada por el Paciente muestra una prevalencia de desnutrición del 72,9% (29,9% desnutrición moderada y 43% desnutrición severa). La desnutrición se relacionó con el tipo de tumor y con el estadío, pero no con la edad, el sexo ni con el Índice de Masa Corporal habitual. Conclusiones: La prevalencia de desnutrición en los pacientes con cáncer evaluados en nuestra consulta es elevada. La valoración nutricional es básica para identificar a aquellos pacientes con desnutrición o riesgo de desnutrición y orientar la necesidad de tratamiento nutricional.

  15. Complex Motor Learning in Four-Year-Olds

    Science.gov (United States)

    Leithwood, K. A.; Fowler, W.

    1971-01-01

    The effects of 4 months of gymnostic training upon complex and simple gross motor abilities and general cognitive and psychosocial functioning in 4-year-olds were compared with the effects of music training and no treatment. (WY)

  16. Testing some common tennis hypotheses: Four years at Wimbledon

    NARCIS (Netherlands)

    Magnus, J.R.; Klaassen, F.J.G.M.

    1996-01-01

    In this paper we investigate the truth (more often the untruth) of seventeen commonly heard statements about tennis. We base our analysis on point-by-point data of almost 500 singles matches played at Wimbledon, 1992-1995. The seventeen hypotheses under consideration are: 1 A player is as good as hi

  17. Testing some common tennis hypotheses : Four years at Wimbledon

    NARCIS (Netherlands)

    Magnus, J.R.; Klaassen, F.J.G.M.

    1996-01-01

    In this paper we investigate the truth (more often the untruth) of seventeen commonly heard statements about tennis.We base our analysis on point-by-point data of almost 500 singles matches played at Wimbledon, 1992-1995.The seventeen hypotheses under consideration are: 1 A player is as good as his/

  18. Effect of the dedicated education unit on nursing student self-efficacy: A quasi-experimental research study.

    Science.gov (United States)

    George, Lynn E; Locasto, Lisa W; Pyo, Katrina A; W Cline, Thomas

    2017-03-01

    Although the Dedicated Education Unit (DEU) has shown initial promise related to satisfaction with the teaching/learning environment, few studies have examined student outcomes related to the use of the DEU as a clinical education model beyond student satisfaction. The purpose of this quantitative, quasi-experimental study was to compare student outcomes from the traditional clinical education (TCE) model with those from the DEU model. Participants were students enrolled in a four-year baccalaureate program in nursing (n = 193) who had clinical education activities in one of three clinical agencies. Participants were assigned to either the DEU or a TCE model. Pre-clinical and post-clinical self-efficacy scores were measured for each group using an adapted Generalized Self-Efficacy Scale (Schwarzer and Jerusalem, 1995). Both groups experienced a significant increase in self-efficacy scores post clinical education. The increase in self-efficacy for the DEU students was significantly greater than the increase in self-efficacy for the traditional students. Self-efficacy is considered an important outcome of nursing education because high self-efficacy has been linked to making an easier transition from student to nursing professional. This study supports the quality of the DEU as a clinical education model by examining student self-efficacy outcomes.

  19. Superior efficacy of new medicines?

    NARCIS (Netherlands)

    Luijn, J.C.F. van; Gribnau, F.W.J.; Leufkens, H.G.M.

    2010-01-01

    PURPOSE: To provide an overview of and discuss newly authorised medicines with an improved efficacy. METHODS: This analysis focussed on new medicines with an improved efficacy based on the results of randomised active control trials. Information on comparative efficacy was obtained from the European

  20. 高师院校师范生教师职业技能四年一体培养的实践与探索%The practice and exploration of four years training of teachers occupation skill of students in teachers college

    Institute of Scientific and Technical Information of China (English)

    张旺君

    2012-01-01

      The teachers' occupation skills include Mandarin and spoken skills, writing Chinese characters and writing skills, teaching skills, working skills. Teachers' occupation skill training need long-term, systematic training, the article under the guidance of new curriculum reform, the cognition to the experience to the practice, to practice and explore four years training of teachers occupation skill of students in teachers college.%  师范生教师职业技能包括普通话和口语表达技能、书写规范汉字和书面表达技能、教学工作技能、班主任工作技能等四部分。教师职业技能的培养需要长期、系统的训练,文章在新课程改革的指引下,对认知到体验再到实践,分层次、分阶段四年一体培养师范生教师职业技能进行了实践与探索

  1. 近4年高考物理“重庆卷”对学生科学探究能力的考查特点分析%A Study on the Characteristics of Physical Questions about the Assessment of Scientific Inquiry Abilities of Chongqing's College Entrance Examination in the Recent Four Years

    Institute of Scientific and Technical Information of China (English)

    廖文; 张正严

    2011-01-01

    This article selects physical questions of college entrance examination of Chongqing in the recent four years as the research objects, to make for the characteristics of physical questions about the assessment of scientific inquiry abilities according to statistics and analysis. The study finds that the average proportion of the questions about the assessment of scientific inquiry abilities is 12.5 % and the questions mainly test students' "analysis and argument ability". The content focuses on electromagnetism and mechanics.%本文以近4年重庆高考物理题为例,统计分析了科学探究试题的各项特征。研究发现,探究题在重庆高考物理题中所占比重平均达12.5%,以考查学生“分析与论证”能力为主。考查内容集中在电学、力学部分。

  2. The efficacy of pivmecillinam

    DEFF Research Database (Denmark)

    Jansåker, Filip; Frimodt-Møller, Niels; Bjerrum, Lars

    2016-01-01

    regimen is superior to a 3-day regimen. With this study we aim to identify and to compare the efficacy of pivmecillinam 400 mg t.i.d in a 3-day respectively 5-day regimen, against community acquired uncomplicated LUTI, i.e., in women at the age of 18-70 year old. METHOD/DESIGN: The general practitioner....... DISCUSSION: Pivmecillinam is an excellent choice against urinary tract infections and we believe this study will fill in the gaps and strengthen the evidence on the treatment against one of the most common infections in our society. Thus, aiming to provide a more rational and ecological beneficial...

  3. 2353例艾滋病患者中医药治疗4年保持率及影响因素研究%Study on the Four-year Retention Rate and Influencing Factors for 2 353 AIDS Patients by Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    梁碧颜; 王健; 陆嘉明; 徐立然; 张国梁; 毛宇湘; 李晓东; 谭行华

    2011-01-01

    Objective To analyze the retention rate and its influencing factors of HIV/AIDS patients by Chinese medicine (CM) maintenance treatment in the first 5 provinces in China. Methods Kaplan-Meier method was used to analyze the retention rate of treatment in patients. Cox hazard regression model was used to assess factors that might influence the treatment time of Chinese medication. Results Totally 2 353 patients took part in this four-year study. Of them, 1 156 (49. 1% ) were male, 2 344 (99.6%) were Hah nationality, 2 260 (96%) were marrried, 2 219 (94. 3% ) had junior middle-schooling or below, the average age was 41.52 ±8.98 years, 1 758 (74. 7% ) received paid blood donation, 478 (20. 3% ) received blood transfusion, 737 (31.3%) were absent of symptoms, 963 (40. 9% ) received combined treatment of CM and Westem medicine. The median time within the four years was 44.84 months. The average retention rate for 1,2, 3, 4 years of CM treatment were 86. 6%, 78. 4%, 72. 2%, 65.6%, respectively. The results of Cox model indicated that the drop-out risk could be reduced in combined treatment of CM and Westem medicine patients ( HR=0. 805, P<0. 01 ) and AIDS patients ( HR =0. 769, P <0.01 ). The drop-out risk could be increased by the infection route of paid blood donation ( HR=1. 373, P<0. 01 ). Conclusions The four-year retention rate of the 2 353 patients by CM treatment in the first 5 provinces in China was 65. 6%. Route of infection, whether or not in combination of Western medicine,and staging showed influence on CM maintenance treatment time.%目的 对我国首批5个省中医药持续治疗艾滋病(HIV/AIDS)患者的4年治疗情况,以及保持治疗的影响因素进行分析.方法 采用乘积极限法计算不同随访时间的治疗保持率,采用Cox比例风险回归模型,对可能影响中医药治疗时间的因素进行分析.结果 共有2 353例患者作为研究对象参加了为期4年的随访,其中男性1 156

  4. Efficacy of antihypertensive drugs.

    Science.gov (United States)

    Dixon, G T; Johnson, E S

    1976-03-01

    The magnitude of the fall in blood-pressure in response to an antihypertensive drug depends on the level of the pretreatment pressure, and there is a direct relationship between the two in that the higher the pretreatment pressure the greater the fall in pressure in response to treatment. This simple relationship is inherent in the practical situation of titrating the diastolic blood-pressures of a group of hypertensive patients to a predetermined level. It is assumed that notionally the dose of an antihypertensive drug can be increased in all patients until the diastolic pressure is reduced to the predetermined level. When the fall in diastolic pressure (deltaD.P.) is plotted against pretreatment diastolic pressure (P.T.D.P.), the points for all patients lie on a straight line of slope unity and negative deltaD.P.-intercept numerically equal to the predetermined diastolic-pressure level. This straight-line relationship is termed the predetermined ideal response line. Analysis of data from clinical trials shows that, despite the variability inherent in the practical situation, the data appear to conform to this straight-line relationship. The method of assessing the efficacy of antihypertensive agents is essentially a comparison of each experimental point with the theoretical predetermined response line. In its simplest form the method consists in constructing a scatter diagram of deltaD.P. against P.T.D.P. for all patients. Patients can then be classified as responders or non-responders according to their position on the diagram relative to the predetermined response line. This method of assessing the efficacy of antihypertensive agents has several advantages, the most important of which is that it provides a simple method for displaying all the relevant information in a readily comparable form.

  5. A comparative study evaluating the clinical efficacy of skin tapes versus silicone gel for the treatment of posttrauma scar in the rabbit model

    Directory of Open Access Journals (Sweden)

    Chih-Chien Wang

    2014-01-01

    Full Text Available Background: Skin tape and silicone gel are two common over-the-counter preparations used to enhance the cosmesis of keloids and hypertrophic scars of posttrauma wounds. This animal study was performed to determine the clinical efficacy of skin tape versus silicone gel in subjects with scars. Materials and Methods: Three New Zealand rabbits that received total 12 incision wounds which two incision wounds on one ear side and subsequent primary suturing were studied. Stitches were removed after 1 week. Silicone gel was applied right upper side of the rabbit′s ear directly on surgical incision wounds, and skin tapes were also applied left upper side of the rabbit′s ear directly on another surgical incision wounds after 1 week of surgery. The lower incisions in both ears were covered with sterilized gauze and served as controls. We compared two experimental groups at binaural with using Vancouver Scar Scale, Manchester Scar Scale, and The Stony Brook Scar Evaluation Scale. These are widely used in clinical practice and research to document change in scar appearance. Results: We describe a rabbit model for incisional wounds and scarring outcome measures. The results of scar measuring devices demonstrated that skin tape reduced scar formation as well as silicone gel. Conclusions: The results of cosmetic demonstrated that skin tape reduced scar formation as well as silicone gel. However, the economical and effective materials were the important subject that suffices for clinical requirement. The application of these scar prevention devices to reduce scar formation after surgical incision is worthy of future investigation. Moreover, skin tape may represent a low-cost alternative and low scar formation for closure of surgical incisions.

  6. Reticence, Accuracy and Efficacy

    Science.gov (United States)

    Oreskes, N.; Lewandowsky, S.

    2015-12-01

    James Hansen has cautioned the scientific community against "reticence," by which he means a reluctance to speak in public about the threat of climate change. This may contribute to social inaction, with the result that society fails to respond appropriately to threats that are well understood scientifically. Against this, others have warned against the dangers of "crying wolf," suggesting that reticence protects scientific credibility. We argue that both these positions are missing an important point: that reticence is not only a matter of style but also of substance. In previous work, Bysse et al. (2013) showed that scientific projections of key indicators of climate change have been skewed towards the low end of actual events, suggesting a bias in scientific work. More recently, we have shown that scientific efforts to be responsive to contrarian challenges have led scientists to adopt the terminology of a "pause" or "hiatus" in climate warming, despite the lack of evidence to support such a conclusion (Lewandowsky et al., 2015a. 2015b). In the former case, scientific conservatism has led to under-estimation of climate related changes. In the latter case, the use of misleading terminology has perpetuated scientific misunderstanding and hindered effective communication. Scientific communication should embody two equally important goals: 1) accuracy in communicating scientific information and 2) efficacy in expressing what that information means. Scientists should strive to be neither conservative nor adventurous but to be accurate, and to communicate that accurate information effectively.

  7. IMAP statement on contraceptive efficacy.

    Science.gov (United States)

    1994-08-01

    Unwanted pregnancy may have serious negative effects upon the health and well-being of individuals and families. The use of effective contraception is therefore important. Efficacy, however, is not the only factor considered by clients when choosing a contraceptive method, so counsellors and service providers should not promote methods on the sole basis of their efficacy, irrespective of client preference. With regard to method efficacy, important considerations which may affect the choice of a method are the availability of emergency contraception and access to safe abortion services in the event of method failure. Biological factors such as age, parity, and whether a woman is breast feeding may affect contraceptive efficacy and should be a consideration when choosing a method. Contraceptive efficacy is usually measured in terms of failure rates calculated from the number of pregnancies which occur during a specified period of contraceptive use. Method failure is that attributable to the method, while user failure is that attributable to incorrect use of the method in addition to method failure. The failure rates for specific methods of contraception reported in the literature vary, sometimes substantially. The article briefly considers the measurement of efficacy and human factors affecting contraceptive efficacy with regard to clients, providers, and managers.

  8. Comportamiento del dengue no grave en los últimos cuatro años en Santander, Colombia / Behavior of simple dengue during the last four years in Santander, Colombia / O comportamento da dengue não é grave nos últimos quatro anos, em Santander, Colômbia

    Directory of Open Access Journals (Sweden)

    Sergio Eduardo Serrano-Gómez, MD., MSc.

    2015-11-01

    the reason why it is currently considered the most emergent infectious disease that causes morbidity and mortality around the world. Objective: Observe simple dengue behavior in the last four years in Santander, Colombia. Method: An analytical study based on secondary data of simple dengue in Santander was performed between the years 2007 and 2015. The weekly epidemiological incidence was calculated and endemic channels between the years of 2012 and 2015 were built using logarithm base 10 with geometric mean and confidence intervals of 95%. The investigation was classified as non-risky according to Law 8430 of 1993, Republic of Colombia. Results: The National Service of Public Health Surveillance (SIVIGILA reported 26.849 cases of simple dengue in Santander between the years of 2007 and 2015. The cutoff points (success, security, risk, and epidemic vary in different zones, with significant statistically differences of 4.2 (in 2007, 2.9 (in 2010, and 8.1 (between 2013 and 2014 for each 100.000 inhabitants. Conclusions: The endemic channels of dengue must be taken into account as well as the impact of calculated incidence for monitoring the disease. According to the secular trend, every 3 to 4 years, there is a peak incidence. It is possible that in 2016 a new and bigger peak incidence of dengue will take place in Santander. It is therefore necessary to consider strategies and immediate measures to control this disease. [Serrano-Gómez SE, De-Montijo C, Rey-Serrano JJ. Behavior of simple dengue during the last four years in Santander, Colombia. MedUNAB 2015; 18 (2: 107-115] Introdução: A transmissão e a incidência do vírus da dengue tem aumentado significativamente ao longo das últimas três décadas, por isso agora é considerada a doença infecciosa re-emergente, que gera aumento da morbidade e mortalidade no mundo. Objetivo: Observar o comportamento da dengue descomplicada nos últimos quatro anos, em Santander, Colômbia. Metodologia: Se fez um estudo anal

  9. Obesity and hormonal contraceptive efficacy.

    Science.gov (United States)

    Robinson, Jennifer A; Burke, Anne E

    2013-09-01

    Obesity is a major public health concern affecting an increasing proportion of reproductive-aged women. Avoiding unintended pregnancy is of major importance, given the increased risks associated with pregnancy, but obesity may affect the efficacy of hormonal contraceptives by altering how these drugs are absorbed, distributed, metabolized or eliminated. Limited data suggest that long-acting, reversible contraceptives maintain excellent efficacy in obese women. Some studies demonstrating altered pharmacokinetic parameters and increased failure rates with combined oral contraceptives, the contraceptive patch and emergency contraceptive pills suggest decreased efficacy of these methods. It is unclear whether bariatric surgery affects hormonal contraceptive efficacy. Obese women should be offered the full range of contraceptive options, with counseling that balances the risks and benefits of each method, including the risk of unintended pregnancy.

  10. Ocorrência dos indicadores de risco para a deficiência auditiva infantil no decorrer de quatro anos em um programa de triagem auditiva neonatal de um hospital público Occurence of risk indicators for hearing loss over four years in a neonatal hearing screening program of a public hospital

    Directory of Open Access Journals (Sweden)

    Eliara Pinto Vieira

    2007-09-01

    Full Text Available OBJETIVO: Comparar a ocorrência dos indicadores de risco para a deficiência auditiva infantil ao longo de quatro anos, em um Programa de Triagem Auditiva Neonatal. MÉTODOS: Foram pesquisados os prontuários de 382 recém nascidos prematuros nascidos no Hospital São Paulo, de 2000 a 2004. RESULTADOS: Em 2000, encontramos 5,9% de casos de antecedentes familiares/consangüinidade, a qual aumentou de forma estatisticamente significante para 13,6% em 2003. A ventilação mecânica aumentou de forma estatisticamente significante de 24,6% casos em 2000, para 40,2% em 2004. O número de convulsões em RN foi de 4,2% em 2000 para 9,8% em 2004, aumento estatisticamente significante. Encontramos 11,0% de casos de infecção congênita em 2000, o que caiu para 4,3% em 2003. No ano de 2002, houve apenas um caso de sífilis, sendo que a ocorrência destas doenças diminuiu nos últimos anos. O HPIV foi de 15,3% no ano 2000 para 5% em 2003, com redução estatisticamente significante. Os casos de malformação caíram de 3,4% no ano 2000 para 0,7% em 2003. Os casos de ototoxicidade diminuíram de forma estatisticamente significante de 43,2% em 2000 para 30,0% em 2003. CONCLUSÃO: A análise estatística revelou aumento significante da ocorrência dos antecedentes familiares para a deficiência auditiva, do uso de ventilação mecânica e das convulsões neonatais. Os casos de infecção congênita e hemorragia periintraventricular diminuíram estatisticamente do ano 2000 para 2004. Os casos de malformação, baixo peso e ototoxicidade variaram de forma aleatória entre os anos estudados. E alguns indicadores de risco se mantiveram sem alterações estatisticamente significantes.PURPOSE: To compare the occurrence of risk indicators for hearing loss in children over a period of four years, in a Neonatal Hearing Screening Program. METHODS: Three hundred and eighty-two files of preterm infants born at Hospital São Paulo in the period from 2000 to 2004 were

  11. Hypogammaglobulinaemia with low natural killer cell numbers:a case report with four year of follow-up%低丙种球蛋白血症伴NK细胞减少:1例原发性免疫缺陷病患儿4年随访

    Institute of Scientific and Technical Information of China (English)

    金莹莹; 王玺; 姚晓红; 陈同辛

    2011-01-01

    Objective To explore the immune characteristic of a patient with hypogammaglobulinaemia and low natural killer(NK)cell numbers. Methods Case histories were analyzed repeatedly to grasp important characteristics of the disease. A routine blood examination and peripheral blood immunological detection was done. Complete neutrophil function test,lymphocyte proliferation ability and cytokine profile were evaluated. Results A 3-year-old boy was referred to the hospital because of fever and abdominal pain as well as partial intestinal obstruction. Laboratory examination revealed low immunoglobulin,reduced absolute numbers of B and NK cells and deficient B cell function of lower IFN-γ and IL-12 production. The patient also had mesenteric lymphadenopathy and a caecal mass with histology suggestive of ileocecal junctional tuberculosis. The patient was infected with cytomegalovirus(CMV)and fungus,which are not common in simple antibody deficiencies. The patient was followed for four years and during this period the patient had recurrent periodontitis resulting in the loss of one tooth. Conclusions Although the precise mechanism of the defect is unclear,we speculate that the case may cast new light on primary immunodeficiencies predominantly with antibody deficiency.(J Clin Pediatr,2011,29(7):601-608)%目的 分析1例低蛋白血症伴NK细胞减少患儿的临床和免疫学特征.方法 详细分析患儿临床资料,并结合实验室血常规检查、淋巴细胞亚群分析、中性粒细胞功能、细胞因子以及淋巴细胞增殖功能分析,来探讨其免疫学特征.结果 收住院的1例3岁男性患儿的主要临床表现是反复发作的发热、腹痛和部分性肠梗阻.免疫学检查显示低丙种球蛋白血症、B细胞和NK细胞绝对计数降低和B细胞功能受损.患儿曾出现肠系膜淋巴结肿大和盲肠肿块,影像学显示回盲部结核感染.患儿病程中曾出现巨细胞病毒和真菌感染,这两种感染对于单纯抗

  12. Clinical retrospective analysis of all-ceramic single crown in terms of fracture resistance with CAD/CAM zirconia-base:a four-year follow-up%CAD/CAM氧化锆全瓷单冠抗折裂随访4年临床分析

    Institute of Scientific and Technical Information of China (English)

    郑茜聪; 蔡志斌

    2015-01-01

    Objective To evaluate the fracture resistance of CAD / CAM zirconia all-ceramic crowns. Methods 284 all-ceramic crowns were fabricated for 189 patients. 226 restorations of 156 patients were clinically followed up for 2. 5-5. 5 years. The site of crown, fracture or breakage,loose or dislodgement were observed. Results The fracture rate was 0. 9% at 1 year after the insertion date, 2. 1% after two years,3. 3% after three years,7. 1% after four years. Overall the fracture rate was 9. 7% with 226 restorations. Base crown fracture took place in two cases. A statistically significant difference was found for fractures when the opposing dentition of natural teeth and fixed restorations were compared (P = 0. 034). The fractures were most commonly noted when the opposing dentition was a fixed metal ceramic or other ceramic restorations. Conclusions The fracture resistance of CAD / CAM zirconia all-ceramic crowns was acceptable clinically and it can be a preferred esthetic restoration.%目的:回顾分析评价CAD / CAM 氧化锆全瓷单冠抗折裂性能。方法为189例患者制作CAD / CAM 氧化锆全瓷冠284颗,随访到156例患者的226颗全瓷冠,随访2.5~5.5年,对修复体的位置、崩瓷、基底冠折断、修复体松动脱落等情况进行观察。结果 CAD / CAM 全瓷冠1年的折裂率0.9%,2年的折裂率为2.1%,3年的折裂率为3.3%,4年的折裂率为7.1%,观察期间全瓷冠的总折裂率为9.7%。其中2例患者发生基底冠折裂。当对颌分别为天然牙或瓷修复体时,全瓷冠的折裂率有显著性差异( P =0.034)。全瓷冠的折裂后牙明显高于前牙区(P <0.01)。结论 CAD / CAM 氧化锆全瓷冠整体抗折裂性能临床可接受,可作为临床首选的美学修复体。

  13. Implementación de un laboratorio de habilidades clínicas centralizado en la Facultad de Medicina de la Universitat de Barcelona: Cuatro años de experiencia Implementation of a centralized clinical skills laboratory at the Medical School of the University of Barcelona: Four years of experience

    Directory of Open Access Journals (Sweden)

    A. Mazarro

    2009-12-01

    implement a centralized skills centre. Materials and methods: We describe the different steps of the process of implementation of this centre and the development of an elective course on clinical skills and procedures, in order to acquire experience in the management of this center and to show to the teachers the usefulness of these facilities. Finally, we investigated the level of acceptance of this tool by teachers and students by using different kinds of questionnaires. Results: In the last four years about 1000 medical students per year (undergraduate and postgraduate have been trained in the laboratory. Students consider that the center is an excellent tool to increase their individual competence in clinical skills and it is necessary to extend this tool to all students. For teachers, the center is a very useful tool to improve clinical training. Conclusions: Our experience has been positive and very useful in the curriculum change process carried out at present in our medical school. The experience could serve as a model for the implementation of skills centers in other Spanish Medical Schools. Medical School must increase the investment in order to improve the facilities and the accessibility of the center to all students and teachers.

  14. A influência do anel na evolução ponderal após quatro anos da derivação gástrica em y-de-roux laparoscópica Ring influence on ponderal evolution after four years of laparoscopic Roux-en-Y gastric bypass

    Directory of Open Access Journals (Sweden)

    Irineu Rasera-Junior

    2012-12-01

    ção do anel ao se analisar exclusivamente a perda de peso.BACKGROUND: Use of ring in Roux-en-Y gastric bypass is still a matter of controversy among bariatric surgeons. There is no consensus on its impact in relation to weight loss and weight maintenance in the long term. AIM: To evaluate the influence of the ring on the evolution of body weight over four years after bariatric surgery. METHODS: Retrospective analyzis of 143 women who underwent laparoscopic Roux-en-Y gastric bypass paired on the use or not use of Silastic® ring. Follow-up time was 48 months. Inclusion criteria were age over 18 years, primary bariatric operation and regular attendance at the clinic during the period of interest for research. The technique kept small gastric reservoir estimated in a volume of 30 ml. The food limb had in average 150 cm and the bile one 40 cm from the duodenojejunal angle. The group "ring" used Silastic® device with length of 6.5 cm, placed 2 cm from gastrojejunal anastomosis. The ring was closed for five polypropylene surgical thread sutures. In the morning after surgery the patients received isotonic fluids; on the second day salty liquid diet and were discharged on the third day. Semisolid diet started from the 20th day and solid on the 30th, with daily tablet of polivitamins. RESULTS: The weight loss was larger on the ring than without ring groups in all periods, respectively 10% and only 5% in the third postoperative year. The proportion of not having reached the 50% excess weight loss expectative was significantly higher in the group without ring than in the group with the ring (31% and 8% respectively in the fourth year. There was no difference between groups in delayed recovery of weight lost with the operation. CONCLUSIONS: The results were favorable to use the ring exclusively when it is analyzed only the weight loss.

  15. Four year's clinical evaluation of glass fiber reinforced resin-bonded fixed partial denture as a periodontal splint to replace lost anterior teeth%玻璃纤维增强复合树脂牙周夹板粘接修复前牙缺失的四年临床观察

    Institute of Scientific and Technical Information of China (English)

    肖遵胜; 姜婷; 方晓倩; 吕品; 李健; 贾璐

    2016-01-01

    restoration,one connector fractured in each year and they were repaired with adhesive resin and the pontics were kept in place for function.In the third and fourth years after restoration,there was one pontic displacement with fracture of connectors.The total survive rate was 83%(25/30) and the functional survival rate was 93% (28/30) at the end of the fourth year.The main reason of failure was fracture of connector.About 22%(13/60) of the adjacent teeth showed marginal bone height decrease,while the other 78% (47/60) increased with statistic significant difference from one year after the restoration to the end of the observation term(P<0.05).The periodontal condition of the adjacent teeth was improved after the restoration.Conclusions The four years clinical evaluation indicates that the GFR-RBFPD may be used as fixed prostheses to replace lost one to three anterior teeth with reduced periodontal support of abutment teeth.

  16. Broken Windows and Collective Efficacy

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    Aldrin Abdullah

    2015-01-01

    Full Text Available The broken windows thesis posits that signs of disorder increase crime and fear, both directly and indirectly. Although considerable theoretical evidence exists to support the idea that disorder is positively related to fear of crime, the empirical literature on examining the indirect effect of the individual’s perception of incivilities on fear of crime is limited, especially in developing countries. This research was conducted to assess the indirect relationship between perceived disorder and fear of crime through collective efficacy. A total of 235 households from Penang, Malaysia, participated in this study. Results reveal that high perception of disorder is negatively associated with collective efficacy. High collective efficacy is associated with low fear of crime. Moreover, a significant and indirect effect of disorder on fear of crime exists through collective efficacy. The results provide empirical support for the broken windows theory in the Malaysian context and suggest that both environmental conditions and interactions of residents play a role in the perceived fear of crime.

  17. Self Efficacy: Operationalizing Challenge Education.

    Science.gov (United States)

    McGowan, Michael L.

    1986-01-01

    Examines self-efficacy theory and how it can be utilized in describing participant change in adventure/challenge programs. Explores connection between personal experience and how people view ability to function in world around them. Discusses Bandura's theory and interaction of sources of information: performance accomplishment, vicarious…

  18. Control efficacy of complex networks

    Science.gov (United States)

    Gao, Xin-Dong; Wang, Wen-Xu; Lai, Ying-Cheng

    2016-06-01

    Controlling complex networks has become a forefront research area in network science and engineering. Recent efforts have led to theoretical frameworks of controllability to fully control a network through steering a minimum set of driver nodes. However, in realistic situations not every node is accessible or can be externally driven, raising the fundamental issue of control efficacy: if driving signals are applied to an arbitrary subset of nodes, how many other nodes can be controlled? We develop a framework to determine the control efficacy for undirected networks of arbitrary topology. Mathematically, based on non-singular transformation, we prove a theorem to determine rigorously the control efficacy of the network and to identify the nodes that can be controlled for any given driver nodes. Physically, we develop the picture of diffusion that views the control process as a signal diffused from input signals to the set of controllable nodes. The combination of mathematical theory and physical reasoning allows us not only to determine the control efficacy for model complex networks and a large number of empirical networks, but also to uncover phenomena in network control, e.g., hub nodes in general possess lower control centrality than an average node in undirected networks.

  19. A conceptual model of referee efficacy.

    Science.gov (United States)

    Guillén, Félix; Feltz, Deborah L

    2011-01-01

    This paper presents a conceptual model of referee efficacy, defines the concept, proposes sources of referee specific efficacy information, and suggests consequences of having high or low referee efficacy. Referee efficacy is defined as the extent to which referees believe they have the capacity to perform successfully in their job. Referee efficacy beliefs are hypothesized to be influenced by mastery experiences, referee knowledge/education, support from significant others, physical/mental preparedness, environmental comfort, and perceived anxiety. In turn, referee efficacy beliefs are hypothesized to influence referee performance, referee stress, athlete rule violations, athlete satisfaction, and co-referee satisfaction.

  20. A conceptual model of referee efficacy

    Directory of Open Access Journals (Sweden)

    Félix eGuillén

    2011-02-01

    Full Text Available This paper presents a conceptual model of referee efficacy, defines the concept, proposes sources of referee specific efficacy information, and suggests consequences of having high or low referee efficacy. Referee efficacy is defined as the extent to which referees believe they have the capacity to perform successfully in their job. Referee efficacy beliefs are hypothesized to be influenced by mastery experiences, referee knowledge/education, support from significant others, physical/mental preparedness, environmental comfort, and perceived anxiety. In turn, referee efficacy beliefs are hypothesized to influence referee performance, referee stress, athlete rule violations, athlete satisfaction, and co-referee satisfaction.

  1. The Pinking Shears: A Novel Tool for Improving Skin Graft Cosmesis

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    Cormac W. Joyce, MB BCh

    2014-12-01

    Full Text Available Summary: A significant aesthetic disadvantage to split skin grafts is the obvious transition between the graft and the normal skin. We report on a novel method to interrupt this transition point by using pinking shears, which are dressmaking scissors with saw-toothed blades that create a chevron pattern instead of a straight edge. We describe a case where the pinking shears were utilized on a split skin graft and Integra for reconstruction of the skin on a volar forearm. This technique allows for breaking-up of the transition point between the skin graft and normal skin and gives rise to an improved aesthetic outcome as the boundary is significantly less well-defined. This novel method shows promise and further study is certainly warranted.

  2. The allegheny general modification of the Harvard Breast Cosmesis Scale for the retreated breast.

    Science.gov (United States)

    Trombetta, Mark; Julian, Thomas B; Kim, Yongbok; Werts, E Day; Parda, David

    2009-10-01

    The use of brachytherapy--and to a lesser extent, external-beam radiotherapy--in the management of locally recurrent breast cancer following ipsilateral breast tumor recurrence (IBTR) followed by repeat breast-conservation surgery and irradiation is currently an area of intense study. The current cosmetic scoring system is inadequate to score the outcome resulting from retreatment because it does not account for the cosmetic effect of the initial treatment. We propose a modification of the scale for patients who undergo retreatment--the Allegheny General Modification of the Harvard/NSABP/RTOG scoring scale.

  3. Thoracoscopy versus thoracotomy improves midterm musculoskeletal status and cosmesis in infants and children.

    Science.gov (United States)

    Lawal, Taiwo A; Gosemann, Jan-H; Kuebler, Joachim F; Glüer, Sylvia; Ure, Benno M

    2009-01-01

    It has been postulated that video-assisted thoracoscopic surgery (VATS) achieves a better biometric and aesthetic outcome than conventional thoracic surgery (CTS), but data are lacking. We aimed to compare the midterm effects of both approaches in children. Sixty-two infants and children, who underwent VATS (34; 55%) or CTS (28; 45%) for benign thoracic conditions, were evaluated at follow-up after a mean of 3.8 years (1 to 7 years). The patients underwent standardized clinical assessment of the skeletal system and function. The intercostal spaces were investigated for rib fusion by ultrasound. Patients (+/- parents) themselves, as well as clinicians, subsequently assessed the scars. Comparing the operated versus nonoperated sides, chest asymmetry was significantly less frequent after VATS versus CTS in the horizontal plane (mean relative difference 0.996 +/- 0.003 vs 0.964 +/- 0.008, p joints did not differ significantly. However, the incidence of scoliosis was lower in VATS patients (9% vs 54%, p intercostal spaces of the operated hemithoraces were narrower after CTS (p < 0.001). The Manchester scar assessment scores were in favor of VATS (mean 7.5 vs 13.1, p < 0.001). The visual analog scale scores recorded by patients-parents and independent observers were also significantly better after VATS. Patient satisfaction was less with CTS as 10% wanted to have the scar revised, compared with none in the VATS group. The thoracoscopic versus conventional approach to the thoracic cavity in children is associated with significantly less midterm musculoskeletal sequelae and a better cosmetic outcome.

  4. Perspectives of Cosmesis following Breast Conservation for Multifocal and Multicentric Breast Cancers

    Directory of Open Access Journals (Sweden)

    Mona P. Tan

    2015-01-01

    Full Text Available Background. Contemporary data suggest that breast conservation treatment (BCT for multifocal and multicentric breast cancer (MFMCBC may be appropriate with noninferior local control rates. However, there is a paucity of data to evaluate patient’s satisfaction with cosmetic outcomes after BCT for MFMCBC. This study was performed to bridge this information gap. Methods. All patients treated at the authors’ healthcare facility were included in the study. Patients with MFMCBC who were assessed to be eligible for BCT underwent tumour resection using standard surgical techniques with direct parenchymal closure through a single incision. After at least three years of follow-up, they were invited to participate in a survey regarding their cosmetic outcomes. Results. Of a total of 160 patients, 40 had MFMCBC, of whom 34 (85% underwent successful BCT. Five-year cancer-specific survival and disease-free survival were 95.7%. Twenty of the 34 patients responded to the survey. No patient rated her cosmetic outcome as “poor.” Analysis indicated low agreement between patients’ self-assessment and clinician-directed evaluation of aesthetic results. Conclusion. BCT for MFMCBC is feasible with acceptable survival and cosmetic outcomes. However, there appears to be a disparity between patient and clinician-directed evaluation of cosmetic results which warrant further research.

  5. Multiscale modeling and distributed computing to predict cosmesis outcome after a lumpectomy

    Science.gov (United States)

    Garbey, M.; Salmon, R.; Thanoon, D.; Bass, B. L.

    2013-07-01

    Surgery for early stage breast carcinoma is either total mastectomy (complete breast removal) or surgical lumpectomy (only tumor removal). The lumpectomy or partial mastectomy is intended to preserve a breast that satisfies the woman's cosmetic, emotional and physical needs. But in a fairly large number of cases the cosmetic outcome is not satisfactory. Today, predicting that surgery outcome is essentially based on heuristic. Modeling such a complex process must encompass multiple scales, in space from cells to tissue, as well as in time, from minutes for the tissue mechanics to months for healing. The goal of this paper is to present a first step in multiscale modeling of the long time scale prediction of breast shape after tumor resection. This task requires coupling very different mechanical and biological models with very different computing needs. We provide a simple illustration of the application of heterogeneous distributed computing and modular software design to speed up the model development. Our computational framework serves currently to test hypothesis on breast tissue healing in a pilot study with women who have been elected to undergo BCT and are being treated at the Methodist Hospital in Houston, TX.

  6. Differences in postoperative outcomes, function, and cosmesis: open versus robotic thyroidectomy.

    Science.gov (United States)

    Lee, Jandee; Nah, Kuk Young; Kim, Ra Mi; Ahn, Yeun Hee; Soh, Euy-Young; Chung, Woong Youn

    2010-12-01

    Robotic thyroidectomy using a gasless transaxillary approach, first described in 2008, has become popular. This study compared outcomes, including postoperative distress and patient satisfaction, for patients undergoing robotic thyroidectomy with those for patients treated by conventional open thyroidectomy. Of 84 prospectively enrolled patients, 41 underwent robotic thyroidectomy (the robot group), and 43 received conventional open thyroidectomy (the open group). All the patients were followed up for at least 3 months after surgery. Videolaryngostroboscopic examinations were performed preoperatively and after 1 week and after 3 months postoperatively. Postoperative pain and discomfort were evaluated using a symptom scale. Subjective voice and swallowing changes were assessed by questionnaires; and satisfaction with cosmetic outcome was measured by verbal response at 3 months. The two groups were similar in age, gender, type of operation, and final pathologic diagnosis. Although the mean operating time was significantly longer with the robotic technique than with open surgery, there were no between-group differences in postoperative pain or duration of hospital stay. No patient in either group experienced any major postoperative complication. Postoperative discomfort in the neck and swallowing disturbances were significantly more frequent in the open group than in the robot group, both at 1 week and at 3 months after surgery. However, there was no significant between-group difference in subjective voice parameters. At 3 months, the mean cosmetic satisfaction score was significantly higher in the robotic than in the open group. Although postoperative pain levels and complications were comparable in the two groups, conventional open thyroidectomy requires a shorter operative time. The robotic technique, however, offers several distinct advantages including very good to excellent cosmetic results, reduced postoperative neck discomfort, and fewer adverse swallowing symptoms.

  7. Efficacy Beliefs of Special Educators: The Relationships among Collective Efficacy, Teacher Self-Efficacy, and Job Satisfaction

    Science.gov (United States)

    Viel-Ruma, Kim; Houchins, David; Jolivette, Kristine; Benson, Gwen

    2010-01-01

    In order to examine the relationship between reported levels of teacher self-efficacy, collective efficacy, and job satisfaction in special educators, teachers in one school district completed three surveys measuring these constructs. The results indicated that teacher self-efficacy had a direct effect on job satisfaction. It was further found…

  8. Short-term cognitive-behavioral therapy for binge eating disorder: long-term efficacy and predictors of long-term treatment success.

    Science.gov (United States)

    Fischer, Sophia; Meyer, Andrea H; Dremmel, Daniela; Schlup, Barbara; Munsch, Simone

    2014-07-01

    The present study evaluates the long-term efficacy (four years after treatment) of a short-term Cognitive-Behavioral Treatment (CBT) of Binge Eating Disorder (BED). We examined patient characteristics, mostly measured at the end of treatment, for their predictive value of long-term success. Forty-one BED-patients between 18 and 70 years took part in a randomized controlled trial (RCT) for a short-term treatment and were evaluated until 4 years after treatment. Assessments comprised structured interviews on comorbid mental disorder/eating disorder pathology and questionnaires on eating disorder pathology/general psychopathology. BED core symptoms and associated psychopathology improved substantially during treatment phase and further improved or at least remained stable during the follow-up period. End of treatment predictors for long term success were elevated weight and eating concern and higher frequency of objective binges. Tailoring additional interventions to patients' individual needs could further improve treatment efficacy.

  9. Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease.

    Science.gov (United States)

    Sosa Estani, S; Segura, E L; Ruiz, A M; Velazquez, E; Porcel, B M; Yampotis, C

    1998-10-01

    A double-blind, randomized, clinical field trial was designed to test the efficacy and tolerance of a specific drug treatment in children in the indeterminate phase of infection by Trypanosoma cruzi. Children were treated with benznidazole at a dose of 5 mg/kg/day for 60 days or placebo and followed-up for 48 months. The treated children showed a significant decrease in geometric mean titers of antibodies against T. cruzi measured by indirect hemagglutination, indirect immunofluorescence, and ELISA. After a four year follow-up, 62% of the benznidazole-treated children and no placebo-treated child were seronegative for T. cruzi when tested by an ELISA using a T. cruzi flagellar calcium-binding protein (F29). Xenodiagnosis carried out after 48 months of follow-up was positive in 4.7% of the benznidazole-treated children and in 51.2% of the placebo-treated children. These results show the tolerance to and efficacy of benznidazole against T. cruzi in seropositive children six to 12 years of age. We used an early serologic marker of cure after treatment, consisting of a recombinant antigen implemented in a rapid, conventional serologic procedure.

  10. Pre-Service Teachers' Mathematics Self-Efficacy and Mathematics Teaching Self-Efficacy

    Science.gov (United States)

    Zuya, Habila Elisha; Kwalat, Simon Kevin; Attah, Bala Galle

    2016-01-01

    Pre-service mathematics teachers' mathematics self-efficacy and mathematics teaching self-efficacy were investigated in this study. The purpose was to determine the confidence levels of their self-efficacy in mathematics and mathematics teaching. Also, the study was aimed at finding whether their mathematics self-efficacy and teaching…

  11. Relationship between Counseling Self-Efficacy and Multicultural Counseling Self-Efficacy among School Counselors

    Science.gov (United States)

    Crook, Tylon

    2010-01-01

    The purpose of this dissertation was to examine the relationship between school counselors' counseling self-efficacy and multicultural counseling self-efficacy. In addition, this study measured school counselors' levels of general school counseling self-efficacy, multicultural counseling self-efficacy, and the relationship between school counselor…

  12. The Relationship between Teacher Efficacy, and Students' Trigonometry Self-Efficacy and Achievement

    Science.gov (United States)

    Sarac, Ayse; Aslan-Tutak, Fatma

    2017-01-01

    The purpose of the present study is to investigate the relationship between teacher efficacy to student trigonometry self-efficacy and student trigonometry achievement. The study included 16 high school teachers and their tenth grade students (n = 571). Teacher efficacy was studied in terms of general teaching efficacy, mathematics teaching…

  13. Self-Efficacy: Conditioning the Entrepreneurial Mindset

    DEFF Research Database (Denmark)

    Neergaard, Helle; Mauer, René; Kirketerp Linstad, Anne

    2009-01-01

    Research that has sought to identify the underlying determinants of self-efficacy is sparse. This chapter seeks to identify antecedents of entrepreneurial self-efficacy and the processes that produce and reinforce self-efficacy. It seeks to broaden our understanding of the self-efficacy concept t...... through an exploration of its origins and via a journey to its impact in the field of entrepreneurship. Finally, it suggests pedagogical initiatives needed to promote entrepreneurial self-efficacy in the different social arenas of life....

  14. Aid Efficacy: An Institutional Approach

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    José Antonio Alonso Rodríguez

    2006-01-01

    Full Text Available This work aims to explore some of the weaknesses that the international aid system presents for efficaciously operating in promoting development. For this, it adopts an institutionalapproach, attempting to investigate the problems of asymmetry in information that occur both in relationships between donor and receiver and within aid organisations. The analysis of these aspects leads the author to underscore the importance that learning processes have in enriching interventions in development; he also underscores the importance of the attitudes and aptitudes of the agents in fostering these processes of improvement in aid quality.

  15. The Efficacy of Soccer Headgear

    Science.gov (United States)

    Ju, Yan-Ying; Broglio, Michael D.; Sell, Timothy C.

    2003-01-01

    Objective: The potential for risks associated with chronic soccer heading has led some soccer leagues to mandate the use of soccer headgear. Although manufacturers have designed and promoted these headbands to decrease the forces associated with heading a soccer ball, their efficacy has not been tested. Therefore, we investigated the efficacy of 3 brands of soccer headgear: Headers, Headblast, and Protector, as compared with a non-headband condition. Design and Setting: A force platform was mounted vertically with each headband attached with a length of hook-and-loop tape. A JUGS Soccer Machine projected balls at the platform and headband at 56.45 kph (35 mph). Measurements: We measured vertical ground reaction force for 50 trials of each condition and calculated peak force, time to peak force, and impulse. Results: We found a significant reduction in peak force of impact with all 3 headbands. The Protector headband also showed the greatest decrease in time to peak force and impulse, whereas the Headers headband showed a significant increase in impulse. Conclusions: All 3 headbands were effective at reducing the peak impact force. The Protector headband appeared the most effective at reducing time to peak force and impulse within the design of this study. The clinical effectiveness of these products remains to be seen. PMID:14608431

  16. Principals' transformational leadership and teachers' collective efficacy.

    Science.gov (United States)

    Dussault, Marc; Payette, Daniel; Leroux, Mathieu

    2008-04-01

    The study was designed to test the relationship of principals' transformational, transactional, and laissez-faire leadership with teachers' collective efficacy. Bandura's theory of efficacy applied to the group and Bass's transformational leadership theory were used as the theoretical framework. Participants included 487 French Canadian teachers from 40 public high schools. As expected, there were positive and significant correlations between principals' transformational and transactional leadership and teachers' collective efficacy. Also, there was a negative and significant correlation between laissez-faire leadership and teachers' collective efficacy. Moreover, regression analysis showed transformational leadership significantly enhanced the predictive capabilities of transactional leadership on teachers' collective efficacy. These results confirm the importance of leadership to predict collective efficacy and, by doing so, strengthen Bass's theory of leadership.

  17. The "Efficacy-Effectiveness Gap"

    DEFF Research Database (Denmark)

    Nordon, Clementine; Karcher, Helene; Groenwold, Rolf H H

    2016-01-01

    BACKGROUND: The concept of the "efficacy-effectiveness gap" (EEG) has started to challenge confidence in decisions made for drugs when based on randomized controlled trials alone. Launched by the Innovative Medicines Initiative, the GetReal project aims to improve understanding of how to reconcile...... paradigms, in which EEG is related to 1) real-life characteristics of the health care system; 2) the method used to measure the drug's effect; and 3) a complex interaction between the drug's biological effect and contextual factors. CONCLUSIONS: The third paradigm provides an opportunity to look beyond any...... dichotomy between "standardized" versus "real-life" characteristics of the health care system and study designs. Namely, future research will determine whether the identification of these contextual factors can help to best design randomized controlled trials that provide better estimates of drugs...

  18. Analysis of Graduation Rates for Four-Year Colleges: A Model of Institutional Performance Using IPEDS

    Science.gov (United States)

    Fung, Terence Yip-hung

    2010-01-01

    Under the George W. Bush U.S. presidential administration, the federal government pushed for greater accountability among institutions of higher education for educational outcomes. Graduation rate is a key performance indicator of institutional accountability. Previous researchers of student attrition focused primarily on the effects of student…

  19. Do cold feet warn of trouble ahead? Premarital uncertainty and four-year marital outcomes.

    Science.gov (United States)

    Lavner, Justin A; Karney, Benjamin R; Bradbury, Thomas N

    2012-12-01

    Are the doubts that people feel before marriage signs of impending difficulties or normative experiences that can be safely ignored? To test these opposing views, we asked 464 recently married spouses whether they had ever been uncertain about getting married and then compared 4-year divorce rates and marital satisfaction trajectories among those partners with and without premarital doubts. Doubts were reported by at least one partner in two thirds of couples. Women with premarital doubts had significantly higher 4-year divorce rates, even when controlling for concurrent marital satisfaction, the difficulty of their engagement, history of parental divorce, premarital cohabitation, and neuroticism. Among intact couples, men's and women's doubts predicted less satisfied marital trajectories. Premarital doubts appear to be common but not benign, suggesting that valid precursors of marital distress are evident during couples' engagements.

  20. Informant-Reported Cognitive Decline and Activity Engagement across Four Years in a Community Sample.

    Science.gov (United States)

    Hosking, Diane E; Jiang, Da; Sargent-Cox, Kerry A; Anstey, Kaarin J

    2017-01-01

    Subtle age-related cognitive decline may be associated with the capacity to remain engaged in mental, physical, and social activities. Informant reports of cognitive decline potentially provide additional information to psychometric tests on change in everyday cognitive function relevant to activity engagement. To investigate relations between decline in everyday cognitive function as assessed by informant report and activity engagement in community-dwelling older adults. A sample of cognitively normal older adults was drawn from the 2 latest waves of the PATH Through Life Study (n = 1,391; mean age 74.5 ± 1.5, 48.4% female). PATH is a 16-year longitudinal cohort study set in the Canberra/Queanbeyan district, Australia. Assessments were carried out at baseline, and at 3 subsequent time-points 4 years apart. At wave-4, the IQCODE, an informant measure of 4-year cognitive decline was provided by a spouse, family member, or friend of each participant. Activity engagement was assessed by the abbreviated RIASEC Mental Activity List, self-reported frequency and duration of physical activity (Whitehall Questionnaire) and the Lubben Social Network Scale that assessed interaction with family/friends. Participants provided demographic information, self-reported health status (SF-12), and responses to the Goldberg Depression Scale. The Symbol Digit Modalities Test (SDMT) and California Verbal Learning Test (CVLT) were used to measure objective 4-year cognitive change. Those with MMSE score of ≤27 were excluded. IQCODE score predicted disengagement from mental activities over 4 years in cognitively healthy adults (β = -0.056, standard error [SE] = 0.019, p = 0.004). This association was robust to covariate control and change on the SDMT which was also significantly related to mental activity disengagement. In models adjusted for change scores on the SDMT and the CVLT, the IQCODE was associated with less physical (β = -0.692, SE = 0.24, p = 0.004) and social engagement (β -0.046, SE = 0.021, p = 0.032), but relationships were attenuated with the inclusion of covariates. Informant-reported cognitive decline in a non-clinical sample was linked to activities that support cognitive health. Associations were robust to adjustment for cognitive change scores. Utilising informant reports prior to the manifestation of clinically relevant decline may identify those who would benefit most from personalised activity interventions. © 2017 S. Karger AG, Basel.

  1. Forty four years of dermatophytes in a Chicago clinic (1944-1988).

    Science.gov (United States)

    Rippon, J W

    1992-07-01

    Data are presented on 39,270 cultures taken over a 44 year span (1944-1988) at the University of Chicago's Dermatology Clinic. In the mid 1940's Microsporum audouinii accounted for 60-80% of isolates. It gradually decreased over the next two decades and disappeared altogether in the 1970's. Trichophyton rubrum, rare in the 1940's accounted for over 60% of isolates in the mid-1960's only to be overtaken by T. tonsurans. This species, not isolated till the mid 1950's, became and remains the dominant dermatophyte at the present time. Both T. mentagrophytes and Epidermophyton floccosum increased in the 1970's and decreased later. Unusual circumstances resulted in clusters of T. verrucosum, T. terrestre, and T. schoenleinii isolates. Infections were associated with rural dairy workers, zoo handlers and immigrant families respectively. M. canis and M. gypseum were steady at a low rate throughout the entire period. Rare isolates included M. cookei, M. persicolor, M. racemosum, T. simii, T. soudanense, T. violaceum, and the soil keratinophile, Aphanoascus fulvescens.

  2. The Process Approach to Clinical Pharmacy Orientation--Four Years' Experience.

    Science.gov (United States)

    Moleski, Ronald J.; Snodgrass, Gary L.

    1979-01-01

    The process approach is an effective method of teaching clinical pharmacy clerkship orientation, the major advantage of which is increased student participation based on improved early identification of predetermined learning outcomes. The primary disadvantage is the difficulty of implementation. A lesson plan is appended. (MLW)

  3. Four-year follow-up of a Wilson disease pedigree complicated with epilepsy and hypopituitarism

    Science.gov (United States)

    Zhang, Qi-Jie; Xu, Liu-Qing; Wang, Chong; Hu, Wei; Wang, Ning; Chen, Wan-Jin

    2016-01-01

    Abstract Rationale: Wilson's disease (WD) is an autosomal recessive inherited disorder of copper metabolism with excellent prognosis if treated timely. However, WD is usually prone to neglect and misdiagnosis at an early stage. We reported a rare WD pedigree, and the clinical features, laboratory tests, and gene mutations were analyzed in detail. Patient concerns: The patient was a 17-year-old and 136-cm-tall girl who presented with limb weakness, combined with multi-organ disorders including blind eye, epilepsy, and hypopituitarism. Diagnoses: Clinical tests showed a low serum ceruloplasmin level, high urinary copper excretion and Kayser-Fleischer (K-F) rings. She carried a compound heterozygous mutations in ATP7B gene (c.2828G>A and c.3884C>T). Her younger brother, as an asymptomatic patient, manifested with elevation of transaminases but without neurological and hepatic symptoms. They were diagnosed as WD finally. Interventions: They were treated with sodium dimercaptosulphonate, supplemented with zinc gluconate, vitamin B6, vitamin C, as well as restriction of dietary copper. Outcomes: The urinary copper excretion and serum transaminase level decreased gradually. The abnormal signals in brainstem and basal ganglia were also remarkably decreased after 4-year of de-copper treatment. Lessons: As to the patients with complicated clinical manifestations, the extrapyramidal symptom and basal ganglia signals should be concerned. The serum ceruloplasmin detection and ATP7B gene mutation screening are necessary. PMID:27930511

  4. A Comparison of Four Year Health Outcomes following Combat Amputation and Limb Salvage

    Science.gov (United States)

    2017-01-25

    JW VB ER VFS MG. References 1. Owens BD, Kragh JF Jr, Wenke JC, Macaitis J, Wade CE, Holcomb JB. Combat wounds in operation Iraqi Freedom and operation...injuries VIII: sequelae of combat injuries. J Am Acad Orthop Surg. 2014 Jan; 22 (1):57–62. doi: 10.5435/JAAOS-22-01-57 PMID: 24382880 34. Flint LJ, Wade CA

  5. Determinants of mortality among one to four years old children in ...

    African Journals Online (AJOL)

    admin

    Results: The results showed that the predictors mother's education, mother's age, marital status, birth order(s) and place of ... Child mortality is a factor that is strongly associated with ... or treatable diseases such as measles, malaria, diarrhea,.

  6. Executive Functioning Predicts Academic Achievement in Middle School: A Four-Year Longitudinal Study

    Science.gov (United States)

    Samuels, William Ellery; Tournaki, Nelly; Blackman, Sheldon; Zilinski, Christopher

    2016-01-01

    Executive functioning (EF) is a strong predictor of children's and adolescents' academic performance. Although research indicates that EF can increase during childhood and adolescence, few studies have tracked the effect of EF on academic performance throughout the middle school grades. EF was measured at the end of Grades 6-9 through 21 teachers'…

  7. Groin Swelling in a Four-Year-Old Boy: Primary Great Saphenous Vein Aneurysm.

    Science.gov (United States)

    Çiçek, Mustafa Cüneyt; Çiçek, Ömer Faruk; Yalçınkaya, Adnan; Taşoğlu, İrfan

    2015-11-01

    Primary venous aneurysm, especially in pediatric population, is a very rare clinical entity. We report a case of primary great saphenous vein aneurysm in a 4-year-old boy. He was initially suspected of suffering from inguinal hernia because the soft mass was detected at the inguinal region when the patient was in the standing position, but color Doppler ultrasonography demonstrated the swelling to be a great saphenous vein aneurysm. We decided that surgery was the best option because of potential risk for thromboembolism. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Acute Promyelocytic Leukemia in Four Year Old Female Child - A Case Report

    Directory of Open Access Journals (Sweden)

    Anirudha V. Kushtagi

    2014-07-01

    Full Text Available Leukemia is the most common malignancy of childhood representing about 30 % of oncohematological diseases diagnosed in children less than 15 years of age. We report the case of a 4 year old girl with acute promyelocytic leukemia whose blasts showed the morphology characteristic of acute promyelocytic leukemia variant. The case is reported because in the paediatric population the acute promyelocytic leukemia is a rare occurrence moreover, it represent a true oncohematology emergency, in this case the laboratory has a significant role since the timing of diagnosis must be very short. It helps in therapeutic protocols compared to conventional therapeutic protocols in Acute Myeloid Leukemia (AML, the introduction of retinoid All-Trans-Retinoic Acid (ATRA, both in children and adults with Acute Promyelocytic Leukemia (APL, has significantly reduced the early mortality.

  9. Late-onset superior mesenteric artery syndrome four years following scoliosis surgery – a case report

    Directory of Open Access Journals (Sweden)

    Abol Oyoun Nariman

    2015-01-01

    Full Text Available Background: Superior mesenteric artery (SMA syndrome has been reported as an uncommon condition of external vascular compression of the SMA particularly after rapid weight loss, body casts, or after corrective surgery for spinal deformities, usually within the first few weeks after surgery. Methods: This is a retrospective report of a case of a non-verbal autistic female patient who started to develop SMA syndrome at the age of 16, 4 years after posterior spinal fusion surgery for scoliosis. She was treated conservatively by increasing oral caloric intake, which resulted in increased body weight and relief of symptoms. Results: Seen at 10 years’ follow up, the patient is doing well, and is functional within the limits of her suboptimal cognitive and verbal conditions. She maintains good trunk balance with solid spinal fusion and intact instrumentation at latest follow up. Conclusion: Spinal surgeons should maintain a high index of suspicion for diagnosis of SMA syndrome even years after scoliosis surgery, especially for patients with communication problems, like the case we present here. Appropriate conservative measures can succeed in relieving the symptoms, increasing body weight, and preventing complications including the risk of death.

  10. Students' Characteristics that Facilitate the Transfer from Two-Year to Four-Year Colleges.

    Science.gov (United States)

    Lee, Valerie E.; Frank, Kenneth A.

    1990-01-01

    Investigates how social and academic background factors influenced transfer to 4-year colleges for 2,500 community college students. Reports that past academic performance was the strongest predictor of eventual transfer. Concludes community colleges contribute to social stratification in higher education. (DB)

  11. Effects of Four Years of Exercise, Language, and Social Interventions on Alzheimer Discourse.

    Science.gov (United States)

    Mahendra, Nidhi; Arkin, Sharon

    2003-01-01

    This article describes a comprehensive cognitive-linguistic intervention program for mild to moderate Alzheimer's disease (AD) patients that provided communication skills practice in the context of health-enhancing and esteem-building community-based activities, physical fitness training and supervised volunteer work. Effects for four participants…

  12. A Four-Year Program to Train Residents in Emergency Medical Services.

    Science.gov (United States)

    Otten, Edward J.; Zink, Brian J.

    1989-01-01

    The University of Cincinnati's comprehensive emergency medicine residency curriculum provides significant practical training in ground and aeromedical transport, disaster work, telemetry communications, and administrative matters. Initial program feedback has been very positive. (MSE)

  13. A four-year follow-up study in fibromyalgia. Relationship to chronic fatigue syndrome

    DEFF Research Database (Denmark)

    Nørregaard, J; Bülow, P M; Prescott, E

    1993-01-01

    The primary objectives of this study were to examine to what extent fibromyalgia patients later on developed presumpted causative somatic diseases and to examine symptoms and muscle strength some years after the diagnosis of fibromyalgia was established. A secondary objective was to describe...... the overlap between fibromyalgia and chronic fatigue syndrome. Only in two of 91 the muscle pain was found to be caused by another somatic disease during the median 4 year follow-up period. In one of the 83 attending subjects a somatic disease associated with muscle symptoms was established at the follow...

  14. Four Year-Olds Use Norm-Based Coding for Face Identity

    Science.gov (United States)

    Jeffery, Linda; Read, Ainsley; Rhodes, Gillian

    2013-01-01

    Norm-based coding, in which faces are coded as deviations from an average face, is an efficient way of coding visual patterns that share a common structure and must be distinguished by subtle variations that define individuals. Adults and school-aged children use norm-based coding for face identity but it is not yet known if pre-school aged…

  15. [Four years of application of the law that decriminalizes euthanasia in Belgium].

    Science.gov (United States)

    Burette, Philippe; Boüüaert, Corinne; Vanmeerbeek, Marc; Giet, Didier

    2008-09-01

    Legislation decriminalizing euthanasia came into effect in Belgium in 2002. Its application is monitored by a federal Commission, which submitted 2 reports to the Parliament, one covering the first 15 months of application and the other the years 2004 and 2005. This article analyzes and comments on the contents of these 2 documents, which provide interesting information on the medical practice of euthanasia in Belgium.

  16. Search for Cosmic Neutrino Point Sources with Four Year Data of the ANTARES Telescope

    CERN Document Server

    Adrián-Martínez, S; Albert, A; André, M; Anghinolfi, M; Anton, G; Anvar, S; Ardid, M; Astraatmadja, T; Aubert, J -J; Baret, B; Basa, S; Bertin, V; Biagi, S; Bigongiari, C; Bogazzi, C; Bou-Cabo, M; Bouhou, B; Bouwhuis, M C; Brunner, J; Busto, J; Capone, A; Carloganu, C; Carr, J; Cecchini, S; Charif, Z; Charvis, Ph; Chiarusi, T; Circella, M; Coniglione, R; Core, L; Costantini, H; Coyle, P; Creusot, A; Curtil, C; De Bonis, G; Decowski, M P; Dekeyser, I; Deschamps, A; Distefano, C; Donzaud, C; Dornic, D; Dorosti, Q; Drouhin, D; Eberl, T; Emanuele, U; Enzenhöfer, A; Ernenwein, J -P; Escoffier, S; Fehn, K; Fermani, P; Ferri, M; Ferry, S; Flaminio, V; Folger, F; Fritsch, U; Fuda, J -L; Galatà, S; Gay, P; Geyer, K; Giacomelli, G; Giordano, V; Gleixner, A; Gómez-González, J P; Graf, K; Guillard, G; Hallewell, G; Hamal, M; van Haren, H; Heijboer, A J; Hello, Y; Hernández-Rey, J J; Herold, B; Hößl, J; Hsu, C C; de Jong, M; Kadler, M; Kalekin, O; Kappes, A; Katz, U; Kavatsyuk, O; Kooijman, P; Kopper, C; Kouchner, A; Kreykenbohm, I; Kulikovskiy, V; Lahmann, R; Lambard, G; Larosa, G; Lattuada, D; Leonora, E; Lefèvre, D; Lim, G; Presti, D Lo; Loehner, H; Loucatos, S; Louis, F; Mangano, S; Marcelin, M; Margiotta, A; Martínez-Mora, J A; Meli, A; Montaruli, T; Morganti, M; Motz, H; Neff, M; Nezri, E; Palioselitis, D; Păvălaş, G E; Payet, K; Petrovic, J; Piattelli, P; Popa, V; Pradier, T; Presani, E; Racca, C; Reed, C; Riccobene, G; Richter, R; Rivière, C; Robert, A; Roensch, K; Rostovtsev, A; Ruiz-Rivas, J; Rujoiu, M; Samtleben, D F E; Sapienza, P; Schmid, J; Schnabel, J; Schuller, J -P; Schüssler, F; Seitz, T; Shanidze, R; Simeone, F; Spies, A; Spurio, M; Steijger, J J M; Stolarczyk, Th; Sánchez-Losa, A; Taiuti, M; Tamburini, C; Trovato, A; Vallage, B; Vallée, C; Van Elewyck, V; Vecchi, M; Vernin, P; Visser, E; Wagner, S; Wijnker, G; Wilms, J; de Wolf, E; Yepes, H; Zaborov, D; Zornoza, J D; Zúñiga, J

    2012-01-01

    In this paper, a time integrated search for point sources of cosmic neutrinos is presented using the data collected from 2007 to 2010 by the ANTARES neutrino telescope. No statistically significant signal has been found and upper limits on the neutrino flux have been obtained. Assuming an $E_{\

  17. Search for Cosmic Neutrino Point Sources with Four Years of Data from the ANTARES Telescope

    Science.gov (United States)

    Adrián-Martínez, S.; Samarai, I. Al; Albert, A.; André, M.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Astraatmadja, T.; Aubert, J.-J.; Baret, B.; Basa, S.; Bertin, V.; Biagi, S.; Bigongiari, C.; Bogazzi, C.; Bou-Cabo, M.; Bouhou, B.; Bouwhuis, M. C.; Brunner, J.; Busto, J.; Capone, A.; Cârloganu, C.; Carr, J.; Cecchini, S.; Charif, Z.; Charvis, Ph.; Chiarusi, T.; Circella, M.; Coniglione, R.; Core, L.; Costantini, H.; Coyle, P.; Creusot, A.; Curtil, C.; De Bonis, G.; Decowski, M. P.; Dekeyser, I.; Deschamps, A.; Distefano, C.; Donzaud, C.; Dornic, D.; Dorosti, Q.; Drouhin, D.; Eberl, T.; Emanuele, U.; Enzenhöfer, A.; Ernenwein, J.-P.; Escoffier, S.; Fehn, K.; Fermani, P.; Ferri, M.; Ferry, S.; Flaminio, V.; Folger, F.; Fritsch, U.; Fuda, J.-L.; Galatà, S.; Gay, P.; Geyer, K.; Giacomelli, G.; Giordano, V.; Gleixner, A.; Gómez-González, J. P.; Graf, K.; Guillard, G.; Hallewell, G.; Hamal, M.; van Haren, H.; Heijboer, A. J.; Hello, Y.; Hernández-Rey, J. J.; Herold, B.; Hößl, J.; Hsu, C. C.; de Jong, M.; Kadler, M.; Kalekin, O.; Kappes, A.; Katz, U.; Kavatsyuk, O.; Kooijman, P.; Kopper, C.; Kouchner, A.; Kreykenbohm, I.; Kulikovskiy, V.; Lahmann, R.; Lambard, G.; Larosa, G.; Lattuada, D.; Leonora, E.; Lefèvre, D.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Mangano, S.; Marcelin, M.; Margiotta, A.; Martínez-Mora, J. A.; Meli, A.; Montaruli, T.; Morganti, M.; Motz, H.; Neff, M.; Nezri, E.; Palioselitis, D.; Păvălaş, G. E.; Payet, K.; Petrovic, J.; Piattelli, P.; Popa, V.; Pradier, T.; Presani, E.; Racca, C.; Reed, C.; Riccobene, G.; Richter, R.; Rivière, C.; Robert, A.; Roensch, K.; Rostovtsev, A.; Ruiz-Rivas, J.; Rujoiu, M.; Samtleben, D. F. E.; Sapienza, P.; Schmid, J.; Schnabel, J.; Schuller, J.-P.; Schüssler, F.; Seitz, T.; Shanidze, R.; Simeone, F.; Spies, A.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th.; Sánchez-Losa, A.; Taiuti, M.; Tamburini, C.; Trovato, A.; Vallage, B.; Vallée, C.; Van Elewyck, V.; Vecchi, M.; Vernin, P.; Visser, E.; Wagner, S.; Wijnker, G.; Wilms, J.; de Wolf, E.; Yepes, H.; Zaborov, D.; Zornoza, J. D.; Zúñiga, J.

    2012-11-01

    In this paper, a time-integrated search for point sources of cosmic neutrinos is presented using the data collected from 2007 to 2010 by the ANTARES neutrino telescope. No statistically significant signal has been found and upper limits on the neutrino flux have been obtained. Assuming an E -2 ν spectrum, these flux limits are at 1-10 ×10-8 GeV cm-2 s-1 for declinations ranging from -90° to 40°. Limits for specific models of RX J1713.7-3946 and Vela X, which include information on the source morphology and spectrum, are also given.

  18. Flipping a Dental Anatomy Course: A Retrospective Study Over Four Years

    Directory of Open Access Journals (Sweden)

    Mahmoud M. Bakr

    2016-01-01

    Full Text Available Flipped classrooms have been successfully used to increase student engagement and support student learning in a range of educational fields, including health education. These advantages for student learning supported implementation of the flipped classroom in introductory sciences and preclinical courses in dental education. We report on a 4-year retrospective study which compared two methods of delivery of a first-year dental anatomy course. The first method used the traditional method, consisting of face to face contact teaching hours, which was compared to a partial flipped classroom, where lecture contact was maintained but practical classes were flipped. A series of online videos demonstrating different practical tasks such as wax carving and tooth identification. An online digital library and online quizzes for self-reflected learning were developed and trialled. Students’ Evaluations of Course (SEC and students’ overall performance in practical and theoretical assessments were used to evaluate the impact on student engagement and success, respectively, after implementation of the modified course offerings. This study evidences the success of the transition to a partially flipped course design. Careful design and consideration of implementation of the flipped classroom method in dental education are recommended to ensure that there is reliable availability of online resources and dedicated teaching staff for construction of resources and delivery of relevant in-class activities.

  19. Father Involvement with Three-to-Four-Year Olds at Home: Giving Fathers a Chance

    Science.gov (United States)

    Betawi, Iman Amy; Abdel Jabbar, Sinaria Kamil; AL Jabery, Mohammad. A.; Zaza, Haidar Ibrahim; Al-Shboul, Muhannad

    2014-01-01

    This study examined fathers' perceptions regarding their home-based activities (HBA) and the influence of fathers' demographic characteristics on their perceptions and practices at home. A total of 396 fathers completed a survey questionnaire describing their demographic information, perceptions and their practices regarding their…

  20. Toxoplasma, Toxocara and Tuberculosis co-infection in a four year old child

    Directory of Open Access Journals (Sweden)

    Bandara Tharaka

    2011-05-01

    Full Text Available Abstract Background Tuberculosis. toxocariasis and toxoplasmosis are among the common infectious causes of lymphadenitis in children. Cases of Toxoplasma gondii and Toxocara spp co-infection have been reported. Case Presentation This case report describes a co-infection of Toxoplasma gondii, Toxocara spp and tuberculosis in a child with chronic lymphadenopathy and eosinophilia. Conclusion The case report highlights two important points. First is the diagnostic challenges that are encountered by clinicians in tropical countries such as Sri Lanka, where lymphadenopathy and eosinophilia with a positive serology commonly point towards a parasitic infection. Secondly the importance of proper history taking and performing the Mantoux test as a first line investigation in a country where the incidence of tuberculosis is low, even in the absence of a positive contact history.

  1. Comparing Perceptions of Campus Crime Severity among Community College and Public Four-Year University Students

    Science.gov (United States)

    Lundstrom, Loren M.

    2010-01-01

    In recent years violent crimes on several university campuses have been highlighted by mass media, drawing national attention to the issue of campus crime. Not all college campuses, however, experience the same level of crime. While community colleges serve roughly half of all undergraduates in the U.S., statistically these public institutions…

  2. Autistic children grow up: an eight to twenty-four year follow-up study.

    Science.gov (United States)

    Wolf, L; Goldberg, B

    1986-08-01

    Eighty questionnaires were sent to parents and/or caregivers of autistic persons diagnosed between 1960-73 at CPRI, a regional assessment and treatment centre. The objective was to determine their present place of residence, functioning ability, language development, program involvement, and seizure activity. The results of this study support evidence that more than 50 percent require long-term institutional care; almost one-third suffer epileptic seizures; there is a persistence of symptoms and difficulty in gaining useful speech; few live independently or are capable of employment.

  3. Prediction of Childhood Behavior Problems over a Four-Year Period.

    Science.gov (United States)

    Leicht, David J.; And Others

    Path analysis was used to discover predictors of personality, school conduct, and distractibility-hyperactivity problems in this 4-year longitudinal study of 173 rural children. While previous studies had shown that children's behavior disorders are related to sex of child, family disruption, IQ, Bender-Gestalt Test scores, and socioeconomic…

  4. Four-year follow-up of pregnancy-associated osteoporosis: a case report.

    Science.gov (United States)

    Takahashi, Naoto; Arai, Itaru; Kayama, Satoru; Ichiji, Kenji; Fukuda, Hironari; Handa, Jun-Ichi; Konno, Shin-Ichi

    2014-01-01

    A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic X-ray showed depressed degenerative vertebrae (T7, T9). One month after the initial examination, thoracic sagittal magnetic resonance imaging showed low intensity areas on T1-weighted imaging and iso-high intensity areas on T2-weighted imaging at T5, 7, 8, 9 and 11. Bone mineral density measured by ultrasound was low (%YAM 76%). The bone metabolic markers were high, suggesting accelerated osteoclast activity. These findings prompted a diagnosis of pregnancy-associated osteoporosis. She was asked to stop breastfeeding and to wear a lumbar brace, and treatment with nutritional calcium, activated vitamin D3, and risedronate sodium was started. Her low back pain almost disappeared after treatment. Bone metabolic markers showed normalization 8 months after the initial examination. Risedronate sodium was stopped 2 years and 2 months after the initial examination. Teriparatide treatment was started because her bone mineral density remained low; however, the osteoblast marker P1NP was not increased 5 months after the start of teriparatide treatment.

  5. Acute stroke unit improves stroke management-four years on from INASC.

    LENUS (Irish Health Repository)

    Shanahan, E

    2015-02-01

    The Irish Heart Foundation carried out the Irish National Audit of Stroke Care (INASC) in 2008. Management practices were significantly poorer than those in the UK Sentinel audits. Since then an acute stroke unit has been established in University Hospital Limerick. A stroke database was established. 12 key indicators of stroke management audited by INASC were identified. Results were compared to those in INASC. 89 stroke patients were admitted. 8 of the 12 key indicators scored significantly better than in INASC. 92.5% had a brain scan within 24hrs (INASC-40%, p = < 0.001). 100% of ischaemic strokes received anti-thrombotics (INASC-85%, p = 0.001). 94% had rehab goals agreed by MDT (22% in INASC p = 0.0000). 55% were treated in stroke unit (2% in INASC, p = 0.0000). MDT input improved with regard to physiotherapy (87% vs 43% in INASC, p = < 0.02) and SALT (74% vs 26%, p = < 0.02). Stroke management has significantly improved from 2008, however some deficiencies remain.

  6. Four-year follow-up of endoscopic gastroplication for the treatment of gastroesophageal reflux disease

    Institute of Scientific and Technical Information of China (English)

    Matthijs; P; Schwartz; J; Rieneke; C; Schreinemakers; André; J; P; M; Smout

    2013-01-01

    AIM:To evaluate the long-term effect of Endocinch treatment for gastroesophageal reflux disease(GERD).METHODS:After unblinding and crossover,50 patients(32 males,18 females; mean age 46 years) with pH-proven chronic GERD were recruited from an initial randomized,placebo-controlled,single-center study,and included in the present prospective open-label follow-up study.Initially,three gastroplications using the Endocinch device were placed under deep sedation in a standardized manner.Optional retreatment was offered in the first year with 1 or 2 extra gastroplications.At baseline,3 mo after(re) treatment and yearly proton pump inhibitor(PPI) use,GERD symptoms,quality of life(QoL) scores,adverse events and treatment failures(defined as:patients using > 50% of their baseline PPI dose or receiving alternative antireflux therapy) were assessed.Intention-to-treat analysis was performed.RESULTS:Median follow-up was 48 mo [interquartile range(IQR):38-52].Three patients were lost to follow-up.In 44% of patients retreatment was done after a median of 4 mo(IQR:3-8).No serious adverse events occurred.At the end of follow-up,symptom scores and4 out of 6 QoL subscales were improved(all P < 0.01compared to baseline).However,80% of patients required PPIs for their GERD symptoms.Ultimately,64% of patients were classified as treatment failures.In 60% a post-procedural endoscopy was carried out,of which in 16% reflux esophagitis was diagnosed.CONCLUSION:In the 4-year follow-up period,the subset of GERD patients that benefit from endoscopic gastroplication kept declining gradually,nearly half opted for retreatment and 80% required PPIs eventually.

  7. Introducing Literacy to Four Year Olds: Creating Classroom Cultures in Three Schools

    Science.gov (United States)

    Gregory, Eve; Williams, Ann; Baker, Dave; Street, Brian

    2004-01-01

    A principal aim of the National Curriculum in England was to ensure equality of opportunity for all children, regardless of race or social class. This aim was strengthened through the introduction of the National Literacy Strategy 10 years later which set out to standardize not just the literacy curriculum itself but also the materials and methods…

  8. Mid-term results after endovascular repair of abdominal aortic aneurysms: a four-year experience.

    Science.gov (United States)

    Dalainas, I; Nano, G; Casana, R; Tealdi Dg, D g

    2004-03-01

    The purpose of this retrospective, single-institution study is to describe a 4-year experience of examining early and late clinical outcomes after endovascular repair of abdominal aortic aneurysm (AAA). Between October 1998 and January 2003, 455 patients were submitted for AAA treatment, of whom 269 underwent open repair and 186 were treated with an endovascular procedure. All endovascular-treated patients underwent preoperative arteriography, contrast enhanced CT scanning or spiral-CT to define the morphological characteristics of the aneurysm, including precise diameter and length measurements. Technical success was achieved in 182 (98%) of the endovascular procedures, as intraoperative conversions to open repair and/or aborted procedures occurred in four patients. The perioperative (30-day) mortality rate was 1% (two patients). During the follow-up period (9-60 months) CT, duplex ultrasound scanning and plain abdominal X-ray evaluation were performed at 3, 6, 12 months, and annually thereafter. Type I endoleak occurred in 12 patients (6.6%), required a further endovascular procedure (11) or late conversion to open repair (1). Type II endoleak occurred in five patients (3%). In our clinical experience the endovascular repair of AAA is a safe and effective technique with good mid-term results in patients at standard and high risk.

  9. Repair of a large furcation perforation: a four-year follow-up.

    Science.gov (United States)

    Ibarrola, Jose L; Biggs, Stephen G; Beeson, Thomas J

    2008-05-01

    This case report describes the management of a large furcation perforation in a maxillary first molar. Although the majority of the pulpal floor was destroyed and the mesiobuccal root was damaged, an attempt was made to repair the defect and restore the tooth. An absorbable gelatin sponge matrix was placed, and the defect was repaired with gray ProRoot mineral trioxide aggregate. Subsequently the endodontic treatment was completed; the tooth was restored and was later used as a fixed partial denture abutment. A 55-month recall showed no evidence of periodontal breakdown, no symptoms, and complete healing of all periradicular lesions.

  10. Eurythmy therapy in chronic disease: a four-year prospective cohort study

    Directory of Open Access Journals (Sweden)

    Willich Stefan N

    2007-04-01

    Full Text Available Abstract Background Many patients with chronic diseases use complementary therapies, often provided by their physicians. In Germany, several physician-provided complementary therapies have been reimbursed by health insurance companies as part of health benefit programs. In most of these therapies, the patient has a predominantly passive role. In eurythmy therapy, however, patients actively exercise specific movements with the hands, the feet or the whole body. The purpose of this study was to describe clinical outcomes in patients practising eurythmy therapy exercises for chronic diseases. Methods In conjunction with a health benefit program, 419 outpatients from 94 medical practices in Germany, referred to 118 eurythmy therapists, participated in a prospective cohort study. Main outcomes were disease severity (Disease and Symptom Scores, physicians' and patients' assessment on numerical rating scales 0–10 and quality of life (adults: SF-36, children aged 8–16: KINDL, children 1–7: KITA. Disease Score was documented after 0, 6 and 12 months, other outcomes after 0, 3, 6, 12, 18, 24, and (SF-36 and Symptom Score 48 months. Results Most common indications were mental disorders (31.7% of patients; primarily depression, fatigue, and childhood emotional disorder and musculoskeletal diseases (23.4%. Median disease duration at baseline was 3.0 years (interquartile range 1.0–8.5. Median number of eurythmy therapy sessions was 12 (interquartile range 10–19, median therapy duration was 119 days (84–188. All outcomes improved significantly between baseline and all subsequent follow-ups (exceptions: KITA Psychosoma in first three months and KINDL. Improvements from baseline to 12 months were: Disease Score from mean (standard deviation 6.65 (1.81 to 3.19 (2.27 (p Adverse reactions to eurythmy therapy occurred in 3.1% (13/419 of patients. No patient stopped eurythmy therapy due to adverse reactions. Conclusion Patients practising eurythmy therapy exercises had long-term improvement of chronic disease symptoms and quality of life. Although the pre-post design of the present study does not allow for conclusions about comparative effectiveness, study findings suggest that eurythmy therapy can be useful for patients motivated for this therapy.

  11. Twenty four year time trends in fats and cholesterol intake by adolescents. Warsaw Adolescents Study

    Directory of Open Access Journals (Sweden)

    Charzewska Jadwiga

    2015-06-01

    Full Text Available The objective of this study was to determine time trends (1982–2006 in total fat intake and changes in fatty acid structure intake in adolescents from Warsaw in view of increasing prevalence of obesity. Data come from four successive surveys randomly selected samples of adolescents (aged 11–15 years old, from Warsaw region. In total 9747 pupils have been examined, with response rate varying from 55% to 87% depending on year. Surveys were done always in the spring season of the year. Food intake was assessed by using 24 hours recall method of consumption by the pupils all products, including enriched, dishes and beverages as well as diet supplements, in the last 24 hours preceding the examination. The content of energy and nutrients was calculated by means of own computer softwares (DIET 2 and 4, taking into account successive revisions of the tables of food composition and nutritional values, as well as current Polish DRI. A significant decreasing trend was found in intake of total fat, of saturated fatty acids (SFA and cholesterol. The percentage of energy from total fat, also decreased both in boys (to 35,1% and girls (to 33,7%, what failed to reach the desired level below 30% of energy from fat which is recommended. Also significant decrease of SFA consumption was not satisfactory enough to approach the values <10% of energy recommended as was from 13% to 15%. Decreasing trends in fat intake was not in accordance with the trend in obesity prevalence in the adolescents as average BMI is going up. To stabilize the health-oriented changes especially in the diets of adolescents, further activity is desired from professionals working with prevention of adolescents obesity.

  12. IQ of Four-Year-Olds Who Go On to Develop Dyslexia

    NARCIS (Netherlands)

    van Bergen, Elsje; de Jong, Peter F.; Maassen, Ben; Krikhaar, Evelien; Plakas, Anna; van der Leij, Aryan

    2014-01-01

    Do children who go on to develop dyslexia show normal verbal and nonverbal development before reading onset? According to the aptitude–achievement discrepancy model, dyslexia is defined as a discrepancy between intelligence and reading achievement. One of the underlying assumptions is that the gen

  13. Writing and Becoming [a Teacher]: Teacher Candidates' Literacy Narratives over Four Years

    Science.gov (United States)

    Parker, Darlene Ciuffetelli

    2010-01-01

    This paper explores narrative inquiry practices in pre-service teacher education program. Written dialogue by teacher candidates provided deep and long term reflection during a 5-year initial teacher education program. This 4-year longitudinal study with 30 teacher candidate participants considers participants' knowledge formation in becoming…

  14. The Changes of Arterial Blood Gases in COPD During Four-year Period

    Science.gov (United States)

    Cukic, Vesna

    2014-01-01

    ABSTRACT Introduction: COPD (Chronic Obstructive Pulmonary Disease) is characterized by airflow limitation that is not fully reversible and that can lead to respiratory failure. Objective: to show the changes of arterial blood gases in COPD during the 4 -year evolution of illness. Material and Methods: The research was done on patients suffering from COPD treated at the Clinic “Podhrastovi” during 2006 and 2007 year. The tested parameters were examined from the date of receiving patient with COPD to hospital treatment in 2006 and 2007 and then followed prospectively until 2010 or 2011 year (the follow-up period was 4 years). There were total 199 treated patients who were chosen at random and regularly attended the control examinations. The study was conducted on adult patients of both sexes, different age group. In each patient the duration of illness was recorded so is sex, age, data of smoking habits, information about the regularity of taking bronchodilator therapy during remissions of disease, about the treatment of disease exacerbations, results of blood gases analysis as follows : pH value, PaO2 (partial pressure of oxygen in arterial blood), PaCO2 (partial pressure of carbon dioxide in arterial blood). All these parameters were measured at the beginning and at the end of each hospital treatment. We took in elaboration data obtained in the beginning of the first hospitalization and at the end of the last hospitalization or at the last control in outpatient department when patient was in stable state. Patients were divided into three groups according to the number of exacerbations per year. Results: there is the statistically significant decrease of PaO2 (p<0.01) and pH, (p<0.05) and an increase of PaCO2 (p<0.01) during follow-up period. But in patients regularly treated in phases of remission and exacerbations of illness the course of illness is slower. The decrease of pH and PaO2 and increase of PaCO2 is statistically significantly smaller in those received regular treatment in phases of remissions (P values are respectively <0.05, <0.01 and <0.01) and exacerbations of illness (p values are respectively: <0.01, <0.01 and <0.05). Conclusion: COPD is characterized with airflow limitation which is progressive in the course of illness, and by the changes in arterial blood gases that can lead to respiratory failure, but that course may be made slower using appropriate treatment during remission and exacerbations of diseases. PMID:24783904

  15. The Changes of Pulmonary Function in COPD During Four-Year Period

    Science.gov (United States)

    Cukic, Vesna; Lovre, Vladimir; Ustamujic, Aida

    2013-01-01

    Conflict of interest: none declared. Introduction COPD (chronic obstructive pulmonary disease) is characterized by airflow limitation that is not fully reversible. OBJECTIVE: to show the changes of pulmonary function in COPD during the 4 -year evolution of illness. Material and Methods The research was done on patients suffering from COPD treated at the Clinic “Podhrastovi” during 2006 and 2007. The tested parameters were examined from the date of receiving patient with COPD to hospital treatment in 2006 and 2007 and then followed prospectively until 2010 or 2011 (the follow-up period was 4 years). There were total 199 treated patients who were chosen at random and regularly attended the control examinations. The study was conducted on adult patients of both sexes, different age group. In each patient the duration of illness was recorded so is sex, age, data of smoking habits, information about the regularity of taking bronchodilator therapy during remissions of disease, about the treatment of disease exacerbations, results of pulmonary functional tests as follows: FVC (forced vital capacity), FEV1 (forced expiratory volume in one second) and bronchodilator reversibility testing. All these parameters were measured at the beginning and at the end of each hospital treatment on the apparatuses of Clinic “Podhrastovi”. We took in elaboration those data obtained in the beginning of the first hospitalization and at the end of the last hospitalization or at the last control in outpatient department when patient was in stable state. Patients were divided into three groups according to the number of exacerbations per year. Results airflow limitation in COPD is progressive; both FVC and FEV1 shows the statistically significant decrease during follow-up period of 4 years (p values / for both parameters/ =0.05) . But in patients regularly treated in phases of remission and exacerbations of illness the course of illness is slower. The fall of FVC and FEV1 is statistically significantly smaller in those received regular treatment in phases of remissions and exacerbations of illness (p values / for both parameters/ =0.01). The number of patients responding properly to bronchodilators decreased statistically significantly in patients with COPD during follow-up period (p=0.05). Conclusion COPD is characterized with airflow limitation which is progressive in the course of illness, but that course may be made slower using appropriate treatment during remission and exacerbations of diseases. PMID:24082829

  16. Association between subjective memory complaints and nursing home placement: a four-year follow-up

    DEFF Research Database (Denmark)

    Waldorff, Frans Boch; Siersma, Volkert; Waldemar, Gunhild

    2009-01-01

    OBJECTIVE: In order to evaluate whether elderly persons with subjective memory complaints may be regarded as a group of potentially vulnerable patients who need close follow-up, we investigated the risk of nursing home placement during a 4-year follow-up period. METHODS: Prospective cohort survey...... with 4-year follow-up in general practice. Cox proportional hazard models were used to examine the influence of risk factors on nursing home placement. RESULTS: A total 758 non-nursing home residents aged 65 years and older consulted the General Practitioners in October and November 2002 of whom 50...

  17. Four years follow-up of 101 children with melamine-related urinary stones.

    Science.gov (United States)

    Yang, Li; Wen, Jian Guo; Wen, Jian Jun; Su, Zhi Qiang; Zhu, Wen; Huang, Chen Xu; Yu, Si Long; Guo, Zhan

    2013-06-01

    The melamine-contaminated milk powder incidence occurred in China in 2008. Many studies have been published regarding the epidemiology, clinical symptoms, diagnosis and treatment of melamine-related urinary stones. The objective of this study is to follow-up the effects of melamine-contaminated milk powder consumption on kidney and body growth in children with melamine-related urinary stones 4 years ago. One hundred and one children with melamine-related urinary stones were followed up by urinalysis, renal function tests and urinary ultrasonography. The data of body weight and height, clinical signs and complications were collected. Eighty normal children without the history of consuming melamine-contaminated milk powder were collected as controls. Eighty-one children with melamine-related urinary stones were successfully followed up. Of 45 cases with melamine-related urinary stones treated conservatively after discharge, 34 disappeared completely, 6 dissolved partially, 1 increased in size and 4 did not change at 4 years follow-up. The percentages of under-height and under-weight infants were significantly higher in melamine-related urinary stones group compared to the controls, respectively (p urinary stones on kidney and bladder was found at 4 years follow-up. However, whether or not melamine-related urinary stones had effect on body growth needs follow-up in future.

  18. Enhancing Critical Thinking, Writing and Disposition Preparedness amongst Four-Year University Teacher Education Students

    Science.gov (United States)

    Lane-Patrice, Libra A.

    2013-01-01

    More and more, critical thinking and writing skills are necessary and of prime significance. Stakeholders across the board are concerned that students are deficient in these vital areas. The purpose of this study was to examine how the employment of specific, targeted and explicit critical thinking and writing instruction could enhance the…

  19. IQ of Four-Year-Olds Who Go on to Develop Dyslexia

    Science.gov (United States)

    van Bergen, Elsje; de Jong, Peter F.; Maassen, Ben; Krikhaar, Evelien; Plakas, Anna; van der Leij, Aryan

    2014-01-01

    Do children who go on to develop dyslexia show normal verbal and nonverbal development before reading onset? According to the aptitude-achievement discrepancy model, dyslexia is defined as a discrepancy between intelligence and reading achievement. One of the underlying assumptions is that the general cognitive development of children who fail to…

  20. The 2nd Fermi GBM Gamma-Ray Burst Catalog: The First Four Years

    CERN Document Server

    von Kienlin, Andreas; Paciesas, William S; Bhat, P N; Bissaldi, Elisabetta; Briggs, Michael S; Burgess, J Michael; Byrne, David; Chaplin, Vandiver; Cleveland, William; Connaughton, Valerie; Collazzi, Andrew C; Fitzpatrick, Gerard; Foley, Suzanne; Gibby, Melissa; Giles, Misty; Goldstein, Adam; Greiner, Jochen; Gruber, David; Guiriec, Sylvain; van der Horst, Alexander J; Kouveliotou, Chryssa; Layden, Emily; McBreen, Sheila; McGlynn, Sinead; Pelassa, Veronique; Preece, Robert D; Rau, Arne; Tierney, Dave; Wilson-Hodge, Colleen A; Xiong, Shaolin; Younes, George; Yu, Hoi-Fung

    2014-01-01

    This is the second of a series of catalogs of gamma-ray bursts (GRBs) observed with the Fermi Gamma-ray Burst Monitor (GBM). It extends the first two-year catalog by two more years, resulting in an overall list of 953 GBM triggered GRBs. The intention of the GBM GRB catalog is to provide information to the community on the most important observables of the GBM detected GRBs. For each GRB the location and main characteristics of the prompt emission, the duration, peak flux and fluence are derived. The latter two quantities are calculated for the 50 - 300 keV energy band, where the maximum energy release of GRBs in the instrument reference system is observed and also for a broader energy band from 10 - 1000 keV, exploiting the full energy range of GBMs low-energy detectors. Furthermore, information is given on the settings and modifications of the triggering criteria and exceptional operational conditions during years three and four in the mission. This second catalog is an official product of the Fermi GBM sci...

  1. Biomass and Nutrient Accumulation in a Cottonwood Plantation - The First Four Years

    Science.gov (United States)

    John K. Francis; James B. Baker

    1981-01-01

    For the first 4 years, height increment of an eastern cottonwood plantation on a clayey soil was greatest in the first growing season; diameter growth was greatest in the second growing season; and annual production of biomass was greatest in the third year. Nitrogen, phosphorus, and possibly magnesium are translocated from leaves into bark and other tissue before leaf...

  2. The Arab spring: Its origins, evolution and consequences… four years on

    Directory of Open Access Journals (Sweden)

    Elfatih A. Abdel Salam

    2015-06-01

    Full Text Available The Middle East and North Africa (MENA have long been laden with tensions and instabilities. However, the recent Arab Uprisings, better known as the Arab Spring, have intensified volatility, turning this “hot-spot” into a veritable tinderbox whose potential for explosion has far-reaching national, regional and global implications. This review analyses and describes the events leading to the Arab Spring. It also examines the impacts and ramifications of the upheavals on the national, regional and international levels. The review argues that the Arab Spring has both changed and charged some of the region’s thorniest problems - from the rise of political Islam to civil wars to rivalries between key regional powers. It raises important questions concerning the impact of the Arab Spring: were these uprisings a deceptive and transient phase of popular anger, or were they a genuine harbinger leading to genuine democratic transition? The review focuses also on the online networking and digital technologies as effective methods of aggregate activism to by-pass state owned media. Finally, the review offers an assessment of whether MENA is destined for a political impasse or that political wisdom and prudence will prevail and save the region from the brink of destruction.

  3. Magnifying loupes versus surgical microscope in endodontic surgery: a four-year retrospective study.

    Science.gov (United States)

    Taschieri, Silvio; Weinstein, Tommaso; Tsesis, Igor; Bortolin, Monica; Del Fabbro, Massimo

    2013-08-01

    The purpose of this retrospective study was to evaluate the 4-year outcome of endodontic microsurgery using two different magnification devices. One-hundred and two teeth in 65 patients were included according to specific selection criteria. Endodontic surgery was performed under surgical microscope as magnification device in 63 teeth in 36 patients, while 39 teeth in 29 patients were treated under magnifying loupes. Thirteen patients did not attend the 4-year follow up. The overall success rate on a patient basis was 91.7% at the 1-year and 90.5% at the 4-year follow up for the group using loupes, while for the group using microscope it was 91.4% at the 1-year and 93.3% at the 4-year follow up. The relative risk was 2.07 (95% confidence interval: 0.31, 13.95) in favour of the group in which microscope was used. No statistically significant difference was found in the treatment outcomes relating to the type of magnification device. © 2011 The Authors. Australian Endodontic Journal © 2011 Australian Society of Endodontology.

  4. TECHNICAL CHARACTERIZATION OF ECO-COMPATIBLE PLASTIC FILMS FOR SOIL SOLARIZATION: FOUR YEARS OF EXPERIMENTS

    Directory of Open Access Journals (Sweden)

    Salvatore Margiotta

    2007-12-01

    Full Text Available Soil solarization relies on solar radiation being converted to heat for the killing of soilborne pathogens. On one hand, this technique can be considered as an environmentally-friendly way to manage soilborne pests, as an alternative of methyl bromide phased-out in 2005, than using chemicals. On the other hand, high employment of traditional plastic sheets in agriculture causes the production of enormous quantities of waste, whose inappropriate management might have negative effects on the environment. In order to determine a reduction of the charge of plastic waste and to facilitate the waste disposal, one of the most interesting approaches, from an environmental point of view, lies in the location of innovatory plastic films such as co-extruded ultrathin films, which are able to reduce the plastic quantity to be managed, and biodegradable laminates, which after a first usage, will spontaneously start up a degradation process that avoids their collection and their consequent disposal. Beside the ecological proprieties of these innovative films, it is necessary to study their technical and agronomical behavior in order to determine their efficiency and the possibility to be used in place of the traditional plastic films. This paper represents a review of the researches carrier out by the Technical Economics Department of the University of Basilicata (Italy in the last years (1999, 2000, 2002 and 2003 on the technical performances of some innovative plastic films used for soil solarization.

  5. Hydraulic properties of four-year old woodchips from a denitrification bed

    Science.gov (United States)

    Denitrification beds are being used to reduce the transport of water-soluble nitrate via subsurface drainage systems to surface water. Only recently has the non-linearity of water flow through woodchips been ascertained. To successfully design and model denitrification beds for optimum nitrate remov...

  6. Four-Year-Olds' Beliefs about How Others Regard Males and Females

    Science.gov (United States)

    Halim, May Ling; Ruble, Diane N.; Tamis-LeMonda, Catherine S.

    2013-01-01

    Children's awareness of how others evaluate their gender could influence their behaviours and well-being, yet little is known about when this awareness develops and what influences its emergence. The current study investigated culturally diverse 4-year-olds' ("N" = 240) public regard for gender groups and whether exposure to factors that…

  7. Intangible Capital: Four years of growth as an open-access scientific publication

    Directory of Open Access Journals (Sweden)

    Pep Simo

    2008-01-01

    Full Text Available This issue opens the fourth volume of the Intangible Capital journal, which makes its way towards the fifth year of publication. As usually, we start this volume by evaluating the previous one and tracing new directions. Among the main contributions during the year 2007, we consider important to highlight the following aspects: the renewal of the scientific indexation agreements, the platform change to OJS, the appointment of a new editor, new members included in the editorial board, the board of reviewers, the change towards a bilingual model, the new financing obtained and, the last but not the least, the work undertaken together with many scientific editors of open access Spanish journals for obtaining the positive evaluation of the CNEAI (National Commission for the Evaluation of the Research Activity and thus, being a proof of scientific excellence.

  8. Plasmodium falciparum malaria occurring four years after leaving an endemic area.

    Science.gov (United States)

    Vantomme, B; Van Acker, J; Rogge, S; Ommeslag, D; Donck, J; Callens, S

    2016-04-01

    We present a case of a 52-year-old woman of Ghanaian origin who developed Plasmodium falciparum malaria 4 years after leaving Africa. She had not returned to an endemic area since. We hypothesize several possible scenarios to explain this infection, of which we believe recrudescence of P. falciparum is the most plausible. This occurred most likely as a consequence of waning immunity several years after leaving a high-transmission area. She recovered after a 3-day treatment with atovaquone/proguanil.

  9. Charting the Course: Four Years of the Thomas W. Payzant School on the Move Prize

    Science.gov (United States)

    d'Entremont, Chad; Norton, Jill; Bennett, Michael; Piazza, Peter

    2012-01-01

    Since 2006, the Thomas W. Payzant School on the Move (SOM) Prize has been awarded annually to a Boston public school that has made significant progress in improving student achievement. This case study identifies the structures and strategies that best serve students in prizewinning schools, provides a profile of each of the four winning schools…

  10. From modernism to socialist realism in four years: Myaskovsky and Asafyev

    Directory of Open Access Journals (Sweden)

    Frolova-Walker Marina

    2003-01-01

    Full Text Available Two outstanding personalities of the Soviet musical life in the 1920's, the composer Nikolay Myaskovsky and the musicologist Boris Asafyev, both exponents of modernism, made volte-faces towards traditionalism at the beginning of the next decade. Myaskovsky's Symphony no. 12 (1931 and Asafyev's ballet The Flames of Paris (1932 became models for Socialist Realism in music. The letters exchanged between the two men testify to the formers uneasiness at the great success of those of his works he considered not valuable enough, whereas the latter was quite satisfied with his new career as composer. The examples of Myaskovsky and Asafyev show that early Soviet modernists made their move away from avant-garde creativity well before they faced any real danger from the bureaucracy.

  11. IQ of Four-Year-Olds Who Go On to Develop Dyslexia

    NARCIS (Netherlands)

    van Bergen, Elsje; de Jong, Peter F.; Maassen, Ben; Krikhaar, Evelien; Plakas, Anna; van der Leij, Aryan

    2014-01-01

    Do children who go on to develop dyslexia show normal verbal and nonverbal development before reading onset? According to the aptitude–achievement discrepancy model, dyslexia is defined as a discrepancy between intelligence and reading achievement. One of the underlying assumptions is that the gen

  12. The Transition Experiences of Re-Enrolling Student Veterans at a Public Four-Year University

    Science.gov (United States)

    Beatty, Patrick J.

    2013-01-01

    The purpose of this constructivist grounded theory study was to describe and illuminate the transition experiences of re-enrolling student veterans. This research question guided the study: What are the barriers and strategies for resolution that re-enrolling student veterans face in their pre- and post-service transition experiences? I conducted…

  13. The Disappeared Ones: Female Student Veterans at a Four-Year College

    Science.gov (United States)

    Heitzman, Amy Claire; Somers, Patricia

    2015-01-01

    Since the end of the military draft in 1973, women have entered military service in greater numbers: Women currently account for 16 percent of active-duty service personnel; by 2035, they will account for 15 percent of the total veteran population (National Center for Veterans Analysis and Statistics 2011). The profile of female veterans differs…

  14. Four Years of Media Habits: Implications for U.S. Army Advertising to the Prime Market

    Science.gov (United States)

    1988-12-01

    X NBA Basketball NSA BASKETBALL X X College Basketball COLLEGE BASKETBALL X X College Basketball Playoffs COLLEGE PLAYOFFS NHL Hockey NHL HOCKEY x x...BASEBALLO 19.65 23.16 21.03 23.73 BASEBALL PLAYOFFS 29.28 32.54 28.79 31.53 WORLD SERIES 44.19 46.61 38.01 48.79 NBA BASKETBALL 20.26 27.41 20.67...SERIES 47.64 46.46 46.57 43.33 NBA BASKETBALL 34.60 39.40 45.32 63.33 COLLEGE BASKETBALL 31.50 35.63 41.09 53.33 COLLEGE PLAYOFFSO NHL HOCKEYb 12.07

  15. Communication technology in the home environment of four-year-old children (Slovenia)

    OpenAIRE

    Jurka Lepicnik Vodopivec; Pija Samec

    2015-01-01

    Hoy en día, no podemos ignorar el hecho de que los niños pequeños están demasiado expuestos a las tecnologías. Solo una acción rápida y una actitud positiva por parte de los adultos puede prevenir consecuencias potencialmente negativas, y preparar a los chicos para una vida donde el uso de tecnologías de la comunicación (TIC) es necesario para el éxito social del individuo. Creemos que resulta importante estudiar la relación de la infancia con las TIC en casa, porque estamos seguros de que la...

  16. Integrating e-Learning and Classroom Learning; Four Years of Asynchronous Learning to Improve Academic Competences

    Directory of Open Access Journals (Sweden)

    Bart Rienties

    2008-06-01

    Full Text Available In an ever-changing world, competencies to process information efficiently are essential. However, several researchers indicate that graduates have limited abilities to solve complex problems in reality. In this paper, a possible solution to increase competences in effective searching, analysing and comparing information is provided. In a blended-learning environment, students had to share information before coming to class. The results of an analysis of four consecutive years of computersupported learning in a master-course indicate that students are willing to share information when conditions are favourable. In addition, a specific redesign of the task, control and social dimension let to increased knowledge sharing. Future research is necessary to assess whether this also has increased performance.

  17. SEARCH FOR COSMIC NEUTRINO POINT SOURCES WITH FOUR YEARS OF DATA FROM THE ANTARES TELESCOPE

    NARCIS (Netherlands)

    Adrian-Martinez, S.; Al Samarai, I.; Albert, A.; Andre, M.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Astraatmadja, T.; Aubert, J-J; Baret, B.; Basa, S.; Bertin, V.; Biagi, S.; Bigongiari, C.; Bogazzi, C.; Bou-Cabo, M.; Bouhou, B.; Bouwhuis, M. C.; Brunner, J.; Busto, J.; Capone, A.; Carloganu, C.; Carr, J.; Cecchini, S.; Charif, Z.; Charvis, Ph; Chiarusi, T.; Circella, M.; Coniglione, R.; Core, L.; Costantini, H.; Coyle, P.; Creusot, A.; Curtil, C.; De Bonis, G.; Decowski, M. P.; Dekeyser, I.; Deschamps, A.; Distefano, C.; Donzaud, C.; Dornic, D.; Dorosti, Q.; Drouhin, D.; Eberl, T.; Emanuele, U.; Enzenhoefer, A.; Ernenwein, J-P; Escoffier, S.; Fehn, K.; Fermani, P.; Ferri, M.; Ferry, S.; Flaminio, V.; Folger, F.; Fritsch, U.; Fuda, J-L; Galata, S.; Gay, P.; Geyer, K.; Giacomelli, G.; Giordano, V.; Gleixner, A.; Gomez-Gonzalez, J. P.; Graf, K.; Guillard, G.; Hallewell, G.; Hamal, M.; van Haren, H.; Heijboer, A. J.; Hello, Y.; Hernandez-Rey, J. J.; Herold, B.; Hoessl, J.; Hsu, C. C.; de Jong, M.; Kadler, M.; Kalekin, O.; Kappes, A.; Katz, U.; Kavatsyuk, O.; Kooijman, P.; Kopper, C.; Kouchner, A.; Kreykenbohm, I.; Kulikovskiy, V.; Lahmann, R.; Lambard, G.; Larosa, G.; Lattuada, D.; Leonora, E.; Lefevre, D.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Mangano, S.; Marcelin, M.; Margiotta, A.; Martinez-Mora, J. A.; Meli, A.; Montaruli, T.; Morganti, M.; Motz, H.; Neff, M.; Nezri, E.; Palioselitis, D.; Pavalas, G. E.; Payet, K.; Petrovic, J.; Piattelli, P.; Popa, V.; Pradier, T.; Presani, E.; Racca, C.; Reed, C.; Riccobene, G.; Richter, R.; Riviere, C.; Robert, A.; Roensch, K.; Rostovtsev, A.; Ruiz-Rivas, J.; Rujoiu, M.; Samtleben, D. F. E.; Sapienza, P.; Schmid, J.; Schnabel, J.; Schuller, J-P; Schuessler, F.; Seitz, T.; Shanidze, R.; Simeone, F.; Spies, A.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th; Sanchez-Losa, A.; Taiuti, M.; Tamburini, C.; Trovato, A.; Vallage, B.; Vallee, C.; Van Elewyck, V.; Vecchi, M.; Vernin, P.; Visser, E.; Wagner, S.; Wijnker, G.; Wilms, J.; de Wolf, E.; Yepes, H.; Zaborov, D.; Zornoza, J. D.; Zuniga, J.

    2012-01-01

    In this paper, a time-integrated search for point sources of cosmic neutrinos is presented using the data collected from 2007 to 2010 by the ANTARES neutrino telescope. No statistically significant signal has been found and upper limits on the neutrino flux have been obtained. Assuming an E-nu(-2).

  18. Four-Year Physical Activity Levels among Intervention Participants with Type 2 Diabetes.

    Science.gov (United States)

    Unick, Jessica L; Gaussoin, Sarah A; Hill, James O; Jakicic, John M; Bond, Dale S; Hellgren, Margareta; Johnson, Karen C; Peters, Anne L; Coday, Mace; Kitzman, Dalane W; Bossart, Suzette; Wing, Rena R

    2016-12-01

    Physical activity (PA) has numerous health benefits, particularly for those with diabetes. However, rates of long-term PA participation are often poor. This study examined the effect of an intensive lifestyle intervention (ILI) on objectively assessed PA for a 4-yr period among older adults with type 2 diabetes. Data from 2400 participants (age = 59.3 ± 6.9 yr, body mass index = 36.1 ± 5.9 kg·m) with accelerometry data from the Look AHEAD trial were included in the analyses. Participants randomized to ILI were instructed to reduce caloric intake and progress to ≥175 min·wk of moderate-to-vigorous-intensity PA (MVPA), whereas those randomized to Diabetes Support and Education (DSE) served as the control group. PA was measured at baseline, year 1, and year 4 using an RT3 accelerometer, and bout-related MVPA (PA ≥3 METs, accumulated in bouts of ≥10 min in duration) was calculated. Despite no differences at baseline (ILI = 93.4 ± 152.7 vs DSE = 88.4 ± 143.6 min·wk), bout-related MVPA was significantly greater in ILI compared with DSE at year 1 (151.0 ± 213.5 vs 87.5 ± 145.1 min·wk, P year 4 (102.9 ± 195.6 vs 73.9 ± 267.5 min·wk, P year 1 (29.1% vs 16.3%, P year 4 (18.3% vs 10.0%, P year 1 maintained this threshold of PA at year 4. However, the majority of ILI participants never achieved the ≥175 min·wk threshold. When measured objectively and compared with DSE, ILI engaged in significantly more bout-related MVPA for a 4-yr period. However, future intervention strategies should target the large percentage of individuals who fail to reach the MVPA goal as result of a lifestyle intervention.

  19. Assessment of social function in four-year-old children with cerebral palsy.

    Science.gov (United States)

    McFadd, Emily; Hustad, Katherine C

    2013-01-01

    To determine whether scores from the social function domain of the Paediatric Evaluation of Disability Inventory (PEDI) would reflect differences among speech-language profile groups for children with cerebral palsy (CP). Thirty-four children with CP participated (mean age = 54.4 months). PEDI social function raw scores, developmentally stratified skill levels, and types of skills mastered at a 75% criterion level were examined. Significant differences were observed in social function scores overall and within early and age-appropriate skills among all profile groups with one exception. Skill mastery varied based on profile group and on developmental age category of each skill. The PEDI appears to capture language delay in children with CP, but it may not be sensitive to the impact of speech intelligibility deficits on social function. Findings call for the development of a new tool that more accurately assesses communicative activities and participation in children with CP.

  20. Obesity and mortality among older Thais: a four year follow up study

    Directory of Open Access Journals (Sweden)

    Prasartkul Pramote

    2010-10-01

    Full Text Available Abstract Background To assess the association of body mass index with mortality in a population-based setting of older people in Thailand. Methods Baseline data from the National Health Examination Survey III (NHES III conducted in 2004 was linked to death records from vital registration for 2004-2007. Complete information regarding body mass index (BMI (n = 15997 and mortality data were separately analysed by sex. The Cox Proportional Hazard Model was used to test the association between BMI and all-cause mortality controlling for demographic, socioeconomic, and health risk factors. Results During a mean follow-up time of 3.8 years (60545.8 person-years, a total of 1575 older persons, (936 men and 639 women had died. A U-shaped and reverse J-shaped of association between BMI and all-cause mortality were observed in men and women, respectively. However there was no significant increased risk in the higher BMI categories. Compared to those with BMI 18.5-22.9 kg/m2, the adjusted hazard ratios (HR of all-cause mortality for those with BMI Conclusions The results of this study support the obesity paradox phenomenon in older Thai people, especially in women. Improvement in quality of mortality data and further investigation to confirm such association are needed in this population.

  1. Personal Strength and Finding Meaning in Conjugally Bereaved Older Adults: A Four-Year Prospective Analysis

    Science.gov (United States)

    Kim, Su Hyun; Kjervik, Diane; Belyea, Michael; Choi, Eun Sook

    2011-01-01

    This study was performed to identify the patterns and mechanisms of the development of personal strength of bereaved older adults over a 4-year period after spousal death. The findings showed that while bereaved older adults, on average, experienced a moderate level of personal strength at 6 months post-spousal death with a slight increase over a…

  2. The Development of Compulsive Internet Use and Mental Health: A Four-Year Study of Adolescence

    Science.gov (United States)

    Ciarrochi, Joseph; Parker, Philip; Sahdra, Baljinder; Marshall, Sarah; Jackson, Chris; Gloster, Andrew T.; Heaven, Patrick

    2016-01-01

    Is compulsive Internet use (CIU) an antecedent to poor mental health, a consequence, or both? Study 1 used a longitudinal design to track the development of CIU and mental health in Grade 8 (N = 1,030 males, 1,038 females, M[subscript age] = 13.7), 9, 10, and 11. Study 2 extended Study 1 by examining the kinds of Internet behaviors most strongly…

  3. MAGNUM project: four years of operation of the fully automated observatory

    Science.gov (United States)

    Kobayashi, Y.; Yoshii, Y.; Minezaki, T.

    2004-10-01

    We present an overview of the MAGNUM (Multicolor Active Galactic Nuclei Monitoring) project and its current status. The MAGNUM project is designed to carry out long-term monitoring observations of many AGN in the optical and near-infrared wavelength regions. For this purpose, we built a 2 m automated telescope as well as a multicolor imaging photometer (MIP)(\\cite{kobayashib}). The telescope is located near the Haleakala summit, at a height of 3050 m, within the area of the University of Hawaii's Haleakala Observatory on the Hawaiian Island of Maui. We have been continuously carrying out observations since early 2001 when the preliminary observations were commenced. We have realized a fully automated operation that is suitable for relatively simple and stable observations over a period of several years.

  4. Radiofrequency Ablation of Renal Tumors: Four-Year Follow-Up Results in 47 Patients

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Soo Dong; Yoon, Seong Guk; Sung, Gyung Tak [Dong-A University College of Medicine, Busan (Korea, Republic of)

    2012-09-15

    To retrospectively evaluate the intermediate results of radiofrequency ablation (RFA) of small renal masses (SRMs). Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contrast-enhanced CT or MRI. To confirm the pathologic criteria of complete ablation, 35 patients underwent a follow-up biopsy. Recurrence was defined as contrast enhancement on imaging studies after 3 months, lesion growth at subsequent imaging, or viable cancer cells on follow-up biopsy. Technical success was achieved in 43 (89.6%) of 48 renal tumors. The mean tumor size was 2.3 cm and the mean follow-up period was 49.6 months. Repeated RFA was necessary in 5 tumors due to incomplete ablation. The overall complication rate was 35.8%, of which 96.2% were mild complications. Serum creatinine levels at 12 months after RFA did not differ from those before RFA (1.28 vs. 1.36 mg/dL). Four patients were found to have recurrence at various follow-up intervals, and distant metastasis was not found in any cases. RFA appears to be a useful treatment for selected patients with SRMs. Our 4-year follow-up results disclose an excellent therapeutic outcome with RFA, while achieving effective local tumor control.

  5. Four years of ozone measurements in the Central Amazon - Absorption mechanisms and reactions within the rainforest

    Science.gov (United States)

    Wolff, Stefan; Ganzeveld, Laurens; Tsokankunku, Anywhere; Saturno, Jorge; Souza, Rodrigo; Trebs, Ivonne; Sörgel, Matthias

    2017-04-01

    The ATTO (Amazon Tall Tower Observatory) site (02°08'38.8''S, 58°59'59.5''W) is located in the remote Amazon rainforest, allowing atmospheric and forest studies away from nearby anthropogenic emission sources. Starting with continuous measurements of vertical mixing ratio profiles of H2O, CO2 and O3 in April 2012 at 8 heights between 0.05 m and 80 m above ground, the longest continuous record of near surface O3 in the Amazon rainforest was established. Black carbon (BC), CO and micrometeorological measurements are available for the same period. During intensive campaigns, NOx was measured as well using the same profile system, and therefore several month of parallel NOx measurements are available. This data allows the analyses of diverse patterns regarding emission, deposition, turbulence and chemical reactions of trace gases within and above the rainforest for several rainy and dry seasons. The remote Amazon generally serves as a sink for O3 which is mainly deposited to the canopy. The deposition depends to a large extent on the aperture of the leaf stomata, which is correlated to temperature, humidity, solar radiation and water availability. Comparing these parameters with the in-canopy and above canopy gradients of O3, considering the turbulent conditions and further chemical reactions of O3 with NOx and VOC molecules, we estimated the role of the forest for the removal of ozone from the atmosphere under different meteorological conditions. We applied the Multi-Layer Canopy Chemical Exchange Model - MLC-CHEM to support the analysis of the observed profiles of NOx and O3. Under pristine conditions, the forest soil is the major source for NO emissions, which are directly reacting with O3 molecules, affecting the O3 gradient within the sub-canopy. We have analyzed differences between model and measurements in sub-canopy NO and O3 mixing ratios by the application of different NO soil emission scenarios and by the performance of several sensitivity analyses to investigate the deposition of O3 and NO2 in the canopy.

  6. Twin pregnancies in the Niger Delta of Nigeria: a four-year review

    Directory of Open Access Journals (Sweden)

    Ibrahim I

    2012-05-01

    Full Text Available Isa Ibrahim,1 Abisoye Oyeyemi,2 Abhulimen Obilahi21Department of Obstetrics, 2Epidemiology Division, Department of Public Health, Ministry of Health, Bayelsa State, NigeriaBackground: The female is programmed to nurture one fetus and to take care of one neonate at a time; hence, twin pregnancy is associated with an increased risk of preterm deliveries, perinatal morbidity, and mortality and maternal complications. This study aimed to determine the twinning rate, and maternal and fetal outcomes of all twin pregnancies managed at the Niger Delta University Teaching Hospital Okolobiri.Methods: The study is a 4-year descriptive retrospective evaluation of twin pregnancies managed at the Niger Delta University Teaching Hospital Okolobiri. Records of all pregnancies, booked and unbooked, managed from January 1, 2007 to December 31, 2010 were reviewed. Details of delivery and maternal and fetal outcomes were obtained using a pro forma designed for the study. Epi Info version 3.5.3 was used for statistical analysis. The Chi-square test was used to test for associations between variables. The level of significance was set at P ≤ 0.05.Results: A total of 1341 deliveries including 41 cases of twin deliveries were recorded during the study period, giving an incidence of 30.6/1000. Twenty-nine (70.7% of the patients were unbooked. The mean gestational age was 33.3 ± 2.6 weeks, and the mean fetal weight was 2.34 ± 0.54 kg. There were 13 perinatal deaths, with a perinatal mortality rate of 158.5/1000. There was no association between booking status and perinatal mortality rate (χ2 = 0.017, P = 1.000. Prematurity was the chief cause of perinatal death (65.4%. Maternal morbidities included anemia, wound infection, and genital sepsis. There were no maternal deaths.Conclusion: The twinning rate was high. There was a high perinatal mortality rate, with prematurity accounting for most of the mortality. There is a need for improved incubation/neonatal care for better outcomes with twin pregnancies in the hospital.Keywords: twin pregnancy, Niger Delta, maternal outcome, perinatal outcome

  7. Collective Bargaining in Four Year Institutions: A Faculty Perspective Viewed through the Easton Model.

    Science.gov (United States)

    Rockman, Ilene F.

    A systems model, developed by David Easton, is used to provide some clarity to many of the issues involved with collective bargaining in American higher education. The model serves as an illustration for understanding how decisions are made, and as a conceptual frame of reference to analyze the political situation. The issues surrounding…

  8. Evaluation of antinuclear antibodies by indirect immunofluorescence and line immunoassay methods': four years' data from Turkey.

    Science.gov (United States)

    Sener, Asli Gamze; Afsar, Ilhan; Demirci, Mustafa

    2014-12-01

    The presence of antinuclear antibodies (ANAs), directed against intracellular antigens, is a hallmark of systemic autoimmune rheumatic diseases. The indirect immunofluorescence (IIF) assay is among the most commonly used routine methods for ANA detection as the screening test. The objective of the study was to evaluate ANA patterns in a 4-year period retrospectively. All 19 996 serum samples that were sent to the Laboratory of Medical Microbiology of the tertiary Hospital by any hospital department between 1 January 2009 and 1 January 2013 with a request to test for ANA, anti-ENA or both were included in the study. Of these samples, 4375 (21.9%) were ANA-IIF-positive and 15621 (78.1%) were ANA-IIF-negative. The presented ANA-positive samples consisted of 2392 (54.67%) homogenous, 818 (18.70%) speckled, 396 (9.05%) centromere, 242 (5.53%) nucleolar, 213 (4.87%) nuclear dots, 178 (4.07%) cytoplasmic (except for actin and golgi), 24 (0.55%) actin, 9 (0.21%) golgi, 53 (1.21%) nuclear membrane and 50 (1.14%) mixed pattern. Totally 7800 samples were examined by LIA. Of these samples, 3440 were positive and 4307 were negative with IIF and LIA. In addition, 22 samples were detected as IIF-positive but LIA-negative, whereas the rest 31 samples were IIF-negative but LIA-positive. ANA patterns in 22 IIF-positive samples were homogenous (9), speckled (5), golgi (4), cytoplasmic (3) and nucleolar (1). SSA/Ro-52, SSB/La and Scl-70 positivity were detected in 31 IIF-negative/LIA-positive samples by LIA. The present study comes forward with its overall scope, which covers 4-year data obtained in tertiary hospital located in the western part of Turkey.

  9. Evaluation of SMAP radiometer level 2 soil moisture algorithms using four years of SMOS data

    Science.gov (United States)

    The objectives of the SMAP (Soil Moisture Active Passive) mission include global measurements of soil moisture at three different spatial resolutions. SMAP will provide soil moisture with a 3-day revisit time at an accuracy of 0.04 m3/m3 The 36 km gridded soil moisture product (L2_SM_P) is primar...

  10. Hypothyroid associated megaesophagus in dogs: four years (2009-2013 study in Hyderabad, India

    Directory of Open Access Journals (Sweden)

    Karlapudi Satish Kumar

    2015-06-01

    Full Text Available Megaoesophagus is uncommon but an important consideration for chronic regurgitation in dogs. Five dogs of various breeds were presented to the Teaching Veterinary Clinical Complex (TVCC at College of Veterinary Science, Hyderabad with signs of chronic regurgitation, loss of weight, lethargy, weakness, dehydration and abnormalities of skin, and hair coat were diagnosed for megaesophagus on barium meal contrast radiography. At the TVCC, radiography and gastroscopy were performed, and the condition was confirmed as megaesophagus. Ancillary hemato-biochemical evaluations revealed normocytic normochromic anemia and mild leukocytosis with normal enzymatic activity in liver and kidneys. The thyroid profile in 80% (n=4/5 dogs showed decreased T3 and T4, and elevated thyroid stimulating hormone (TSH levels confirming hypothyroidism. Ultrasonography of abdomen eliminated obstructions in the gastro-intestinal tract and other systemic conditions. Echocardiographic observations were normal in all the dogs. Treatment with metoclopramide (dosed at 5 mg/kg bwt and levothyroxine (dosed at 20 μg/kg bwt and modified management practices involving feeding and diets were successful in controlling the regurgitation in dogs and resulted in good clinical recovery within 20-30 days of post-treatment.

  11. Screening of thalassaemia carriers in intermediate school of Latium: results of four years' work.

    Science.gov (United States)

    Silvestroni, E; Bianco, I; Graziani, B; Carboni, C; Valente, M; Lerone, M; D'Arca, S U

    1980-06-01

    From 1975 to 1979 the Rome Microcythaemia Centre carried out four health education campaigns and thalassaemia screenings among students of the intermediate schools throughout Latium, under the auspices and with the financial support of the Health Authorities of the Latium region. This project is aimed at avoiding reproduction by pairs of thalassaemia carriers and the birth of homozygous children. During the four campaigns 138 501 students were examined, that is, 70 to 76% of those enrolled. Of these 3343 were found to be thalassaemic. Thus the overall prevalence of thalassaemia in Latium is 2.41%, with minor fluctuations from one province to another and, above all, a slight, though definite, trend towards higher values in the southern part of Latium bordering on Campania. The screening was welcomed by the population and the thalassaemic families, there were no detectable negative side-effects, and it resulted in an increased awareness of the problem of the thalassaemias.

  12. Prehypertension and Chronic Kidney Disease in Chinese Population: Four-Year Follow-Up Study.

    Directory of Open Access Journals (Sweden)

    Hao Xue

    Full Text Available Hypertension is a well established cause of chronic kidney disease (CKD. However, the effect of prehypertension on risk of CKD is controversial. The aim of this study is to determine whether prehypertension increases the risk of CKD events in the Chinese population. We enrolled 20,034 with prehypertension and 12,351 with ideal blood pressure in this prospective study. CKD was defined as an estimated glomerular filtration rate (eGFR <60 ml/min 1.73 m2. The new occurrences of CKD events were collected during follow-up. Cumulative survival and freedom for the occurrence of new CKD events was analyzed using the Kaplan-Meier approach. Multivariate Cox Regression was used to analyze the effect of prehypertension on CKD. The median follow-up time was 47 (interquartile range 44-51 months. 601 new onset CKD events occurred during the follow-up period. The cumulative incidence of new CKD events was higher in the prehypertensive population than that in the ideal blood pressure population (2.10% vs 1.46%, P = 0.0001. Multivariate Cox Regression showed that relative risks (RRs for the new onset CKD events in the prehypertensive population were 1.69 (95% confidence intervals (CI: 1.41~2.04, P = 0.001 higher than those in the ideal blood pressure population. Similarly, the risks were 1.68 (95% CI: 1.33~2.13 P = 0.001 times higher in females and 2.14 (95% CI: 1.58~2.91 P = 0.001 times higher in males by adjustment for traditional CV risk factors. Our findings demonstrated prehypertension is an independent risk factor for the occurrence of new CKD events in the Chinese population.

  13. Enhancing Critical Thinking, Writing and Disposition Preparedness amongst Four-Year University Teacher Education Students

    Science.gov (United States)

    Lane-Patrice, Libra A.

    2013-01-01

    More and more, critical thinking and writing skills are necessary and of prime significance. Stakeholders across the board are concerned that students are deficient in these vital areas. The purpose of this study was to examine how the employment of specific, targeted and explicit critical thinking and writing instruction could enhance the…

  14. Student Organization Advisor Motives to Volunteer at Four-Year Institutions of Higher Education

    Science.gov (United States)

    Meyer, Robert A.; Kroth, Michael

    2010-01-01

    Many higher education institutions require student organization advisors to be employees. Such requirements can be interpreted as barriers to students and can limit the number and types of groups found on college campuses. Using quantitative analysis, this study investigates the motivation of student organization advisors at six public…

  15. First-Generation College Students' Persistence at a Four-Year College: A Phenomenological Case Study

    Science.gov (United States)

    Holodick-Reed, Jocelyn A.

    2013-01-01

    First-generation college students differ in their backgrounds and experiences from other college students and are more likely to drop out of college than continuing-generation students (Ishitani & Snider, 2004; Lohfink & Paulsen, 2005). The purpose of this phenomenological case study was to describe the experiences of first-generation…

  16. Effects of Four Years of Exercise, Language, and Social Interventions on Alzheimer Discourse.

    Science.gov (United States)

    Mahendra, Nidhi; Arkin, Sharon

    2003-01-01

    This article describes a comprehensive cognitive-linguistic intervention program for mild to moderate Alzheimer's disease (AD) patients that provided communication skills practice in the context of health-enhancing and esteem-building community-based activities, physical fitness training and supervised volunteer work. Effects for four participants…

  17. A Four Year Follow-Up of Non-Returning Students at Montgomery College.

    Science.gov (United States)

    Gell, Robert L.; And Others

    An annual survey of non-returning Montgomery College students from the years 1971 to 1973 was conducted in order to examine reasons for choosing to leave the college, identify trends, determine the status of students at the time of the survey, and assess the impact of their college experience on current activities. The 454 usable responses (20…

  18. How Is IGE Doing in the Elementary Schools? A Four-Year Survey of IGE Principals.

    Science.gov (United States)

    Paden, Jon S.

    This report summarizes the responses of principals of elementary schools participating in the I/D/E/A Change Program to a survey questionnaire that focuses on program implementation and selected efforts that may be associated with Individually Guided Education (IGE). Survey data are presented for the school years 1973-74, 1974-75, 1975-76, and…

  19. Whole System Thinking: Working with K-12 and Four-Year Partners to Boost Student Success

    Science.gov (United States)

    Collett, Stacy

    2013-01-01

    As they closed the books on the 2012-2013 school year, Long Beach City College continued the task of pouring over years of student enrollment data. They found that after years of offering remedial courses for students who entered unprepared for the rigors of higher education, the college reported and astonishing 500 percent increase in the number…

  20. New non-Gaussian feature in COBE-DMR Four Year Maps

    CERN Document Server

    Magueijo, J

    2000-01-01

    We extend a previous bispectrum analysis of the Cosmic Microwave Background temperature anisotropy, allowing for the presence of correlations between different angular scales. We find a strong non-Gaussian signal in the ``inter-scale'' components of the bispectrum: their observed values concentrate close to zero instead of displaying the scatter expected from Gaussian maps. This signal is present over the range of multipoles $\\ell=6 -18$, in contrast with previous detections. We attempt to attribute this effect to galactic foreground contamination, pixelization effects, possible anomalies in the noise, documented systematic errors studied by the COBE team, and the effect of assumptions used in our Monte Carlo simulations. Within this class of systematic errors the confidence level for rejecting Gaussianity varies between 97% and 99.8%.

  1. Limits on Fast Radio Bursts from Four Years of the V-FASTR Experiment

    CERN Document Server

    Burke-Spolaor, Sarah; Brisken, Walter F; Deller, Adam T; Majid, Walid A; Palaniswamy, Divya; Thompson, David R; Tingay, Steven J; Wagstaff, Kiri L; Wayth, Randall B

    2016-01-01

    The V-FASTR experiment on the Very Long Baseline Array was designed to detect dispersed pulses of milliseconds duration, such as fast radio bursts (FRBs). We use all V-FASTR data through February 2015 to report V-FASTR's upper limits on the rates of FRBs, and compare these with re-derived rates from Parkes FRB detection experiments. V-FASTR's operation at lambda=20 cm allows direct comparison with the 20 cm Parkes rate, and we derive a power-law limit of \\gammaS)\\propto S^\\gamma. Using the previously measured FRB rate and the unprecedented amount of survey time spent searching for FRBs at a large range of wavelengths (0.3 cm > \\lambda > 90 cm), we also place frequency-dependent limits on the spectral distribution of FRBs. The most constraining frequencies place two-point spectral index limits of \\alpha_{20cm}^{4cm} -7.6, where fluence F \\propto f^\\alpha if we assume true the burst rate reported by Champion et al. (2016) of R(F~0.6 Jy ms) = 7 x 10^3 sky^{-1} day^{-1} (for bursts of ~3 ms duration). This upper...

  2. A quality-driven physician compensation model: four-year follow-up study.

    Science.gov (United States)

    Chung, Richard S; Chernicoff, Helen O; Nakao, Kimberly A; Nickel, Robert C; Legorreta, Antonio P

    2003-01-01

    This case report describes a qualitative and preliminary quantitative assessment of a quality-based physician compensation program. The Hawaii Medical Service Association's Physician Quality and Service Recognition program offers an innovative and effective approach for improving delivery of high-quality and cost-effective care to patients enrolled in preferred provider organizations. Support for the program is demonstrated through increasing numbers of voluntarily participating physicians. Preliminary assessment of population outcomes reveals sustained improvements in many clinical areas and mixed findings in others. This study contributes to the body of knowledge available to payers and policy makers considering alternative payment methods to reward improved performance.

  3. Furan in commercially processed foods: four-year field monitoring and risk assessment study in Korea.

    Science.gov (United States)

    Kim, Tae-Kyu; Lee, Yun-Kyung; Kim, Simhae; Park, Young Sig; Lee, Kwang-Geun

    2009-01-01

    The aim of this study was to monitor and assess the risk associated with the presence of furan in various food products consumed in Korea. An optimized analytical method was used for the analysis of furan levels. The optimized solid-phase microextraction (SPME) fiber exposure conditions as follows for temperature, time, and amount of sample were 50 degrees C, 20 min, and 5 g (ml), respectively. Furan was detected in all food samples tested, at levels ranging from 0.4 ng/g in canned crab to 814 ng/g in ground roasted coffee powder. The furan levels in coffee, canned fish, canned meats, sauce, soup, retort, canned vegetables, baby foods, nutritional/diet drinks, confectionary and biscuits and snacks, juice, jams, and canned fruit were (ng/g) 169, 56.1, 30.1, 21.1, 18.1, 15.6, 10.9, 10.6, 7.1, 5.4, 3.7, 3.2, and 2.9, respectively. Furan concentrations in baby food products were between 1 and 102.5 ng/g. The total exposure estimate of furan was determined to be 10.6 ng/kg/d (maximum, 20 ng/kg/d) for adults, and 17.4 ng/kg/d (maximum. 84.9 ng/kg/d) for babies. Exposure estimates found in this study are lower than those prescribed by the U.S. Food and Drug Administration (FDA).

  4. Emergent Literacy Performance across Two Languages: Assessing Four-Year-Old Bilingual Children

    Science.gov (United States)

    Westerveld, Marleen F.

    2014-01-01

    There are few emergent literacy assessments available for bilingual children. This study investigated the usefulness of a screening battery of oral language and print-related measures as an assessment tool for bilingual Samoan-English speaking children. A total of 18 children were recruited from three Samoan language immersion kindergartens (Aoga…

  5. Cataract surgery rates in latin america: a four-year longitudinal study of 19 countries.

    Science.gov (United States)

    Lansingh, Van C; Resnikoff, Serge; Tingley-Kelley, Kimberly; Nano, María E; Martens, Marion; Silva, Juan C; Duerksen, Rainald; Carter, Marissa J

    2010-03-01

    To collect cataract surgery rates data in 19 Latin American countries over a 4-year period as data published to date have been limited. Cataract surgery rates were obtained from National Society of Ophthalmology, National VISION 2020/Prevention of Blindness Committee and Ministry of Health representatives for each country for 2005 to 2008. Economic (gross national income per capita) and other data were collected from publicly available databases. Linear and power correlations between gross national incomes and cataract surgery rates were calculated. Over the study period, most countries increased their cataract surgery rates, with the largest increases observed for Venezuela (186%), Nicaragua (183%), Costa Rica (100%), Uruguay (97%), and Peru (88%). Mean cataract surgery rates for 2005, 2006, 2007, and 2008 for the ensemble of countries were 1545, 1684, 1660, and 1822 per million population, respectively, with a growth over the study period of 17.9%, concurrent with an increase of 57 million (11.5%) in the population. A good correlation between cataract surgery rate and gross national income per capita was found (P < .001). Although progress is being made in the region, the cataract surgery rates represent only one parameter. When they are examined in the context of cataract surgical coverage it is clear that substantial proportions of bilaterally blind persons are still not receiving surgery.

  6. IQ of Four-Year-Olds Who Go on to Develop Dyslexia

    Science.gov (United States)

    van Bergen, Elsje; de Jong, Peter F.; Maassen, Ben; Krikhaar, Evelien; Plakas, Anna; van der Leij, Aryan

    2014-01-01

    Do children who go on to develop dyslexia show normal verbal and nonverbal development before reading onset? According to the aptitude-achievement discrepancy model, dyslexia is defined as a discrepancy between intelligence and reading achievement. One of the underlying assumptions is that the general cognitive development of children who fail to…

  7. Four years (2011-2015) of total gaseous mercury measurements from the Cape Verde Atmospheric Observatory

    Science.gov (United States)

    Read, Katie A.; Neves, Luis M.; Carpenter, Lucy J.; Lewis, Alastair C.; Fleming, Zoe L.; Kentisbeer, John

    2017-04-01

    Mercury is a chemical with widespread anthropogenic emissions that is known to be highly toxic to humans, ecosystems and wildlife. Global anthropogenic emissions are around 20 % higher than natural emissions and the amount of mercury released into the atmosphere has increased since the industrial revolution. In 2005 the European Union and the United States adopted measures to reduce mercury use, in part to offset the impacts of increasing emissions in industrialising countries. The changing regional emissions of mercury have impacts on a range of spatial scales. Here we report 4 years (December 2011-December 2015) of total gaseous mercury (TGM) measurements at the Cape Verde Observatory (CVO), a global WMO-GAW station located in the subtropical remote marine boundary layer. Observed total gaseous mercury concentrations were between 1.03 and 1.33 ng m-3 (10th, 90th percentiles), close to expectations based on previous interhemispheric gradient measurements. We observe a decreasing trend in TGM (-0.05 ± 0.04 ng m-3 yr-1, -4.2 % ± 3.3 % yr-1) over the 4 years consistent with the reported decrease of mercury concentrations in North Atlantic surface waters and reductions in anthropogenic emissions. The decrease was more visible in the summer (July-September) than in the winter (December-February), when measurements were impacted by air from the African continent and Sahara/Sahel regions. African air masses were also associated with the highest and most variable TGM concentrations. We suggest that the less pronounced downward trend inclination in African air may be attributed to poorly controlled anthropogenic sources such as artisanal and small-scale gold mining (ASGM) in West Africa.

  8. Fracture patterns in the maxillofacial region: a four-year retrospective study

    Science.gov (United States)

    2015-01-01

    Objectives The facial bones are the most noticeable area in the human body, and facial injuries can cause significant functional, aesthetic, and psychological complications. Continuous study of the patterns of facial bone fractures and changes in trends is helpful in the prevention and treatment of maxillofacial fractures. The purpose of the current clinico-statistical study is to investigate the pattern of facial fractures over a 4-year period. Materials and Methods A retrospective analysis of 1,824 fracture sites was carried out in 1,284 patients admitted to SMG-SNU Boramae Medical Center for facial bone fracture from January 2010 to December 2013. We evaluated the distributions of age/gender/season, fracture site, cause of injury, duration from injury to treatment, hospitalization period, and postoperative complications. Results The ratio of men to women was 3.2:1. Most fractures occurred in individuals aged between teens to 40s and were most prevalent at the middle and end of the month. Fractures occurred in the nasal bone (65.0%), orbital wall (29.2%), maxillary wall (15.3%), zygomatic arch (13.2%), zygomaticomaxillary complex (9.8%), mandibular symphysis (6.5%), mandibular angle (5.9%), mandibular condyle (4.9%), and mandibular body (1.9%). The most common etiologies were fall (32.5%) and assault (26.0%). The average duration of injury to treatment was 6 days, and the average hospitalization period was 5 days. Eighteen postoperative complications were observed in 17 patients, mainly infection and malocclusion in the mandible. Conclusion This study reflects the tendency for trauma in the Seoul metropolitan region because it analyzes all facial fracture patients who visited our hospital regardless of the specific department. Distinctively, in this study, midfacial fractures had a much higher incidence than mandible fractures. PMID:26734557

  9. Four years prospective study of the maxillofacial trauma at a tertiary center in Western Nepal

    Directory of Open Access Journals (Sweden)

    Rajib Khadka

    2014-01-01

    Full Text Available Purpose: This study was conducted to find the epidemiological characteristics of maxillofacial trauma in the Western region of Nepal. Materials and Methods: All the trauma patients attending the Department of Oral and Maxillofacial surgery in 4 years period at a tertiary center in Western Nepal were included in the study. The incidence, prevalence, age and sex distribution, etiologies and types as well as seasonal and daily variation of maxillofacial trauma were studied. Results: Maxillofacial trauma with male (71.55% predominance was seen. Road traffic accidents (RTA, 46.5% were the most common cause, and 41.65% of fracture cases due to RTA were under the influence of alcohol. Accidents were more common on the rural roads (38.9%, and majorities (43.3% were due to motorcycle accidents. They were more common on Friday (36.7% and in winter seasons (51.2%. The mandible fractures (65.85% were more common than midface fractures (53.58% and 19.44% of the fractures were combined fractures. Parasymphysis in mandible (32.16% and zygoma (39.09% in midface were the most common type of fracture. Conclusion: The increased incidence of maxillofacial trauma following RTA under the influence of alcohol noted in this study reveals the need for formulating preventive measures in the Western region of Nepal. Need to aware people to avoid drink and drive proper traffic management, prevention of carrying excessive passengers, especially on the rooftop of vehicles on the highway and disposal of out of date vehicles and timely maintenance of faulty roads is a must.

  10. Pure Air`s Bailly scrubber: A four-year retrospective

    Energy Technology Data Exchange (ETDEWEB)

    Manavi, G.B.; Vymazal, D.C. [Pure Air, Allentown, PA (United States); Sarkus, T.A. [Dept. of Energy, Pittsburgh, PA (United States)

    1997-12-31

    Pure Air`s Advanced Flue Gas Desulfurization (AFGD) Clean Coal Project has completed four highly successful years of operation at NIPSCO`s Bailly Station. As part of their program, Pure Air has concluded a six-part study of system performance. This paper summarizes the results of the demonstration program, including AFGD performance on coals ranging from 2.0--2.4% sulfur. The paper highlights novel aspects of the Bailly facility, including pulverized limestone injection, air rotary sparger for oxidation, wastewater evaporation system and the production of PowerChip{reg_sign} gypsum. Operations and maintenance which have led to the facility`s notable 99.47% availability record are also discussed. A project company, Pure Air on the Lake Limited Partnership, owns the AFGD facility. Pure Air was the turn key contractor and Air Products and Chemicals, Inc. is the operator of the AFGD system.

  11. The Precursors of Reading Ability in Young Readers: Evidence from a Four-Year Longitudinal Study

    Science.gov (United States)

    Oakhill, Jane V.; Cain, Kate

    2012-01-01

    We report a longitudinal study investigating the predictors of reading comprehension and word reading accuracy between the ages of 7 to 8 (UK Year 3) and 10 to 11 years (Year 6). We found that different skills predicted the development of each. Reading comprehension skill measured in Year 3 was a strong predictor of comprehension in Year 6;…

  12. Risk of impaired glucose tolerance in normal weight hirsute women during four years observation.

    Science.gov (United States)

    Andries, Magdalene; Glintborg, Dorte; Andersen, Marianne

    2010-08-01

    Hirsutism is a common disorder affecting 5-20% of women in reproductive age. Only limited follow-up data exist regarding the prognosis for glucose tolerance and metabolic risk factors in hirsutism. Sixty-nine Caucasian hirsute women underwent a clinical examination and an oral glucose tolerance test (OGTT) during 1997-2002 (baseline) and during 2003-2004 (re-evaluation). The observation period was (median; range) 4 (2-7) years. During re-evaluation, body mass index (BMI) was 24.9 (22.4-29.0) kg/m(2) and total Ferriman-Gallwey score was 10 (7-15) (median; 25-75% quartile). The women had unchanged BMI compared to baseline but increased fasting and 2 hour glucose levels. Impaired OGTT outcome during follow-up was seen in 14/66 (21.2%) women, 5/66 (7.6%) developed diabetes. Women who took oral contraceptives had a significantly decreased area under the curve (AUC) for insulin during follow-up, whereas AUC glucose levels increased. The present data supported a high risk of diabetes in only moderately overweight hirsute women.

  13. Relative stability of core groups in pollination networks in a biodiversity hotspot over four years.

    Directory of Open Access Journals (Sweden)

    Qiang Fang

    Full Text Available Plants and their pollinators form pollination networks integral to the evolution and persistence of species in communities. Previous studies suggest that pollination network structure remains nested while network composition is highly dynamic. However, little is known about temporal variation in the structure and function of plant-pollinator networks, especially in species-rich communities where the strength of pollinator competition is predicted to be high. Here we quantify temporal variation of pollination networks over four consecutive years in an alpine meadow in the Hengduan Mountains biodiversity hotspot in China. We found that ranked positions and idiosyncratic temperatures of both plants and pollinators were more conservative between consecutive years than in non-consecutive years. Although network compositions exhibited high turnover, generalized core groups--decomposed by a k-core algorithm--were much more stable than peripheral groups. Given the high rate of turnover observed, we suggest that identical plants and pollinators that persist for at least two successive years sustain pollination services at the community level. Our data do not support theoretical predictions of a high proportion of specialized links within species-rich communities. Plants were relatively specialized, exhibiting less variability in pollinator composition at pollinator functional group level than at the species level. Both specialized and generalized plants experienced narrow variation in functional pollinator groups. The dynamic nature of pollination networks in the alpine meadow demonstrates the potential for networks to mitigate the effects of fluctuations in species composition in a high biodiversity area.

  14. A Twenty-Four-Year-Old Woman with Left Flank Lipoma-Like Hibernoma

    Directory of Open Access Journals (Sweden)

    R.E. Shackelford

    2017-05-01

    Full Text Available A 24-year-old woman presented with a 5-month history of a left flank mass that was painful on palpation. Magnetic resonance imaging revealed a 10.0 × 6.0 × 2.5 cm mass consistent with lipoma. A fatty lobulated mass was excised and subjected to H&E staining and immunohistochemical analyses. The specimen consisted of mature univacuolated adipocytic cells, with intermixed multivacuolated eosinophilic granular cells. No atypia or hyperchromasia was identified. Most of the cells were S100 positive and Ki-67 immunonegative. A diagnosis of a lipoma-like hibernoma was rendered. Hibernomas are rare benign lipomatous tumors that show differentiation toward brown fat. The lipoma-like hibernoma subtype is rare and can be misdiagnosed as atypical lipoma or well-differentiated liposarcoma. Here we describe an example of this rare tumor.

  15. Warming and nitrogen fertilization effects on winter wheat yields in northern China varied between four years

    DEFF Research Database (Denmark)

    Liu, Liting; Hu, Chunsheng; Olesen, Jørgen E

    2013-01-01

    per m2. This suggests that the wheat yield loss may be related to reduction of spike number, which was affected by decreased soil water content under warming. Warming tended to give larger yield reductions at higher nitrogen fertilizer rates, and this may be related to larger water consumption......Global warming is expected to affect wheat productivity significantly, but with large regional differences depending on current climatic conditions. We conducted a study that aimed to investigate how wheat growth and development as well as yield and yield components respond to warming combined...... with nitrogen fertilization. Infrared heaters were applied above the crop and soil to provide a warming of around 2 °C at 5 cm soil depth during the whole winter wheat growing season from 2008 to 2012 at a site near Shijiazhuang in the North China Plain. Two temperature levels (warming and ambient) for winter...

  16. Twenty-four years of follow-up for a Hanford plutonium wound case.

    Science.gov (United States)

    Carbaugh, Eugene H; Lynch, Timothy P; Antonio, Cheryl L; Medina-Del Valle, Fernando

    2010-10-01

    A 1985 plutonium puncture wound resulted in the initial deposition of 48 kBq of transuranic alpha activity, primarily 239+240Pu and 241Am, in a worker's right index finger. Surgical excisions in the week following reduced the long-term residual wound activity to 5.4 kBq, and 164 DTPA chelation therapy administrations over 17 mo resulted in urinary excretion of about 7 kBq. The case was published in 1988, but now 24 y of follow-up data are available. Annual bioassays have included in-vivo measurements of 241Am in the wound, skeleton, liver, lung, and axillary lymph nodes, and urinalyses for plutonium and 241Am. These measurements have shown relatively stable levels of 241Am at the wound site, with gradually increasing amounts of 241Am detected in the skeleton. Liver measurements have shown erratic detection of 241Am, and the lung measurements indicate Am but as interference from activity in the axillary lymph nodes and skeleton rather than activity in the lung. Urine excretion of Pu since termination of chelation therapy has typically ranged from 10 to 20 mBq d, with Am excretion about 10% of that for 239+240Pu. Annual routine medical exams have not identified any adverse health effects associated with the intake.

  17. Dutch healthcare professionals inadequately perceived if three- and four-year-old preschool children were overweight

    NARCIS (Netherlands)

    Bocca, Gianni; Corpeleijn, Eva; Broens, Jasper; Stolk, Ronald P; Sauer, Pieter J

    2016-01-01

    Aim: We studied whether healthcare professionals adequately perceived if preschool children were overweight and whether this was influenced by their own body mass index (BMI). Methods: We sent 716 Dutch healthcare professionals questionnaires containing seven pictures and seven sketches of three- an

  18. PAVEd for Success: An Evaluation of a Comprehensive Preliteracy Program for Four-Year-Old Children

    Science.gov (United States)

    Schwanenflugel, Paula J.; Hamilton, Claire E.; Neuharth-Pritchett, Stacey; Restrepo, M. Adelaida; Bradley, Barbara A.; Webb, Mi-Young

    2010-01-01

    The purpose of the study was to evaluate the effectiveness of "PAVEd for Success," comprehensive preliteracy program guidelines to support the development of foundational preliteracy skills in 4 year olds. Prekindergarten teachers received professional development on variables of the program that included a summer institute, after-school…

  19. THE SECOND FERMI GBM GAMMA-RAY BURST CATALOG: THE FIRST FOUR YEARS

    Energy Technology Data Exchange (ETDEWEB)

    Von Kienlin, Andreas; Greiner, Jochen; Gruber, David [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Meegan, Charles A.; Bhat, P. N.; Briggs, Michael S.; Burgess, J. Michael; Chaplin, Vandiver; Connaughton, Valerie; Goldstein, Adam [University of Alabama in Huntsville, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Paciesas, William S.; Cleveland, William [Universities Space Research Association, 320 Sparkman Drive, Huntsville, AL 35805 (United States); Bissaldi, Elisabetta [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, I-34127 Trieste (Italy); Byrne, David; Fitzpatrick, Gerard; Foley, Suzanne [School of Physics, University College Dublin, Belfield, Stillorgan Road, Dublin 4 (Ireland); Collazzi, Andrew C. [Astrophysics Office, ZP 12, NASA-Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gibby, Melissa; Giles, Misty [Jacobs Technology, Inc., Huntsville, AL 35806 (United States); Guiriec, Sylvain [NASA-Goddard Space Flight Center, Greenbelt, MD 20771 (United States); and others

    2014-03-01

    This is the second of a series of catalogs of gamma-ray bursts (GRBs) observed with the Fermi Gamma-ray Burst Monitor (GBM). It extends the first two-year catalog by two more years, resulting in an overall list of 953 GBM triggered GRBs. The intention of the GBM GRB catalog is to provide information to the community on the most important observables of the GBM detected GRBs. For each GRB the location and main characteristics of the prompt emission, the duration, peak flux and fluence are derived. The latter two quantities are calculated for the 50-300 keV energy band, where the maximum energy release of GRBs in the instrument reference system is observed and also for a broader energy band from 10-1000 keV, exploiting the full energy range of GBMs low-energy detectors. Furthermore, information is given on the settings and modifications of the triggering criteria and exceptional operational conditions during years three and four in the mission. This second catalog is an official product of the Fermi GBM science team, and the data files containing the complete results are available from the High-Energy Astrophysics Science Archive Research Center.

  20. Four-year surveillance for ochratoxin a and fumonisins in retail foods in Japan.

    Science.gov (United States)

    Aoyama, Koji; Nakajima, Masahiro; Tabata, Setsuko; Ishikuro, Eiichi; Tanaka, Toshitsugu; Norizuki, Hiroko; Itoh, Yoshinori; Fujita, Kazuhiro; Kai, Shigemi; Tsutsumi, Toru; Takahashi, Masanori; Tanaka, Hiroki; Iizuka, Seiichiro; Ogiso, Motoki; Maeda, Mamoru; Yamaguchi, Shigeaki; Sugiyama, Kei-Ichi; Sugita-Konishi, Yoshiko; Kumagai, Susumu

    2010-02-01

    Between 2004 and 2007 we examined foods from Japanese retail shops for contamination with ochratoxin A (OTA) and fumonisins B(1), B(2), and B(3). A total of 1,358 samples of 27 different products were examined for OTA, and 831 samples of 16 different products were examined for fumonisins. The limits of quantification ranged from 0.01 to 0.5 microg/kg for OTA and 2 to 10 microg/kg for the fumonisins. OTA was detected in amounts higher than limits of quantification in wheat flour, pasta, oatmeal, rye, buckwheat flour and dried buckwheat noodles, raisins, wine, beer, coffee beans and coffee products, chocolate, cocoa, and coriander. OTA was found in more than 90% of the samples of instant coffee and cocoa, and the highest concentration of OTA, 12.5 microg/kg, was detected in raisins. The concentration of OTA in oatmeal, rye, raisins, wine, and roasted coffee beans varied remarkably from year to year. Fumonisins were detected in frozen and canned corn, popcorn grain, corn grits, cornflakes, corn soups, corn snacks, beer, soybeans, millet, and asparagus. The highest concentrations of fumonisins B(1), B(2), and B(3) were detected in corn grits (1,670, 597, and 281 microg/kg, respectively). All of the samples of corn grits were contaminated with fumonisins, and more than 80% of the samples of popcorn grain and corn snacks contained fumonisins. OTA and fumonisins were detected in several food products in Japan; however, although Japan has not set regulatory levels for these mycotoxins, their concentrations were relatively low.

  1. The Influence of the Pell Grant on Four Year Degree Production: A Panel Data Analysis

    Science.gov (United States)

    Williams, David S., II

    2014-01-01

    An increased amount of energy and effort has been focused on higher education and degree attainment in the United States. President Obama has recently tied the Pell grants into the discussion as a central point in his proposed system of higher education accountability. However, the influence of the Pell grant on degree production has not been…

  2. Risk of impaired glucose tolerance in normal weight hirsute women during four years observation

    DEFF Research Database (Denmark)

    Andries, Magdalene; Glintborg, Dorte; Andersen, Marianne

    2010-01-01

    Hirsutism is a common disorder affecting 5-20% of women in reproductive age. Only limited follow-up data exist regarding the prognosis for glucose tolerance and metabolic risk factors in hirsutism. Sixty-nine Caucasian hirsute women underwent a clinical examination and an oral glucose tolerance t...

  3. Anthroposophic therapy for chronic depression: a four-year prospective cohort study

    Directory of Open Access Journals (Sweden)

    Willich Stefan N

    2006-12-01

    Full Text Available Abstract Background Depressive disorders are common, cause considerable disability, and do not always respond to standard therapy (psychotherapy, antidepressants. Anthroposophic treatment for depression differs from ordinary treatment in the use of artistic and physical therapies and special medication. We studied clinical outcomes of anthroposophic therapy for depression. Methods 97 outpatients from 42 medical practices in Germany participated in a prospective cohort study. Patients were aged 20–69 years and were referred to anthroposophic therapies (art, eurythmy movement exercises, or rhythmical massage or started physician-provided anthroposophic therapy (counselling, medication for depression: depressed mood, at least two of six further depressive symptoms, minimum duration six months, Center for Epidemiological Studies Depression Scale, German version (CES-D, range 0–60 points of at least 24 points. Outcomes were CES-D (primary outcome and SF-36 after 3, 6, 12, 18, 24, and 48 months. Data were collected from July 1998 to March 2005. Results Median number of art/eurythmy/massage sessions was 14 (interquartile range 12–22, median therapy duration was 137 (91–212 days. All outcomes improved significantly between baseline and all subsequent follow-ups. Improvements from baseline to 12 months were: CES-D from mean (standard deviation 34.77 (8.21 to 19.55 (13.12 (p Conclusion In outpatients with chronic depression, anthroposophic therapies were followed by long-term clinical improvement. Although the pre-post design of the present study does not allow for conclusions about comparative effectiveness, study findings suggest that the anthroposophic approach, with its recourse to non-verbal and artistic exercising therapies can be useful for patients motivated for such therapies.

  4. Test-Enhanced Learning in Competence-Based Predoctoral Orthodontics: A Four-Year Study.

    Science.gov (United States)

    Freda, Nicolas M; Lipp, Mitchell J

    2016-03-01

    Dental educators intend to promote integration of knowledge, skills, and values toward professional competence. Studies report that retrieval, in the form of testing, results in better learning with retention than traditional studying. The aim of this study was to evaluate test-enhanced experiences on demonstrations of competence in diagnosis and management of malocclusion and skeletal problems. The study participants were all third-year dental students (2011 N=88, 2012 N=74, 2013 N=91, 2014 N=85) at New York University College of Dentistry. The 2013 and 2014 groups received the test-enhanced method emphasizing formative assessments with written and dialogic delayed feedback, while the 2011 and 2012 groups received the traditional approach emphasizing lectures and classroom exercises. The students received six two-hour sessions, spaced one week apart. At the final session, a summative assessment consisting of the same four cases was administered. Students constructed a problem list, treatment objectives, and a treatment plan for each case, scored according to the same criteria. Grades were based on the number of cases without critical errors: A=0 critical errors on four cases, A-=0 critical errors on three cases, B+=0 critical errors on two cases, B=0 critical errors on one case, F=critical errors on four cases. Performance grades were categorized as high quality (B+, A-, A) and low quality (F, B). The results showed that the test-enhanced groups demonstrated statistically significant benefits at 95% confidence intervals compared to the traditional groups when comparing low- and high-quality grades. These performance trends support the continued use of the test-enhanced approach.

  5. Gosudarstvennaja programma pereselenija sootechestvennikov: chetyre goda spustja [The state repatriation programme: four years later

    Directory of Open Access Journals (Sweden)

    Kirillova Yelena

    2010-01-01

    Full Text Available This article analyses the problems of the state voluntary repatriation programme and describes its key functions and implementation mechanisms. The author identifies the causes of deceleration in the repatriation process as well as the weak points of the Programme and the ways to improve it. The article offers data on the resettlement of compatriots over the three years of the Programme implementation, its demographic structure, and the regions of resettlement.

  6. The Ancient Habitability of Gale Crater, Mars, after Four Years of Exploration by Curiosity

    Science.gov (United States)

    Vasavada, Ashwin R.; Gupta, Sanjeev; Mars Science Laboratory Science Team

    2016-10-01

    The Mars Science Laboratory (MSL) Curiosity rover landed in August 2012 with the goal of assessing the habitability of environments dating from the Noachian-Hesperian boundary, a time when Mars was undergoing a major climatic change from wetter to drier conditions. The stratified and mineralogically diverse foothills of Gale crater's central mound, Aeolis Mons, retain a record of this key period. Prior to reaching Aeolis Mons, ancient habitable environments were found on the surrounding plains. At Yellowknife Bay, geological, geochemical, and mineralogical analyses of the lacustrine Sheepbed mudstone indicated a near-neutral pH and low salinity environment with the key chemical elements required by life and potential sources of energy to fuel microbial metabolism. As the rover traversed across the plains, evidence for ancient fluvial and deltaic systems pointed toward the hypothesis that lower Aeolis Mons was built up from sediments deposited within a series of lakes that once filled the central basin of the crater. Upon reaching the mountain in September 2014, Curiosity found an array of fluvial, lacustrine, and aeolian strata that also show a complex pattern of post-depositional alteration. The basal outcrops that form the lowest stratigraphic unit of Aeolis Mons, the Murray formation, are characterized predominantly by mudstones with minor intercalated sandstones. The mudstone facies show abundant fine-scale planar laminations throughout the Murray formation succession and are interpreted to record deposition in an ancient lacustrine system in Gale crater. Curiosity has explored 40 m of the ~ 200-m thick Murray formation. If the entire section is lacustrine, it would imply that lakes were stable in Gale crater over a period of at least millions of years, challenging present climate models that cannot account for the temperate and humid conditions needed to sustain long-lived open lakes on early Mars. This presentation will review how Curiosity's geological and atmospheric (e.g., methane and isotopic signatures) observations have changed our view of the ancient habitability of Mars.

  7. Attempting to restore mountain big sagebrush (Artemisia tridentata ssp. vaseyana) four years after fire

    Science.gov (United States)

    Restoration of shrubs is increasingly needed throughout the world because of altered fire regimes, anthropogenic disturbance, and over-utilization. The native shrub mountain big sagebrush (Artemisia tridentata Nutt. ssp. vaseyana (Rydb.) Beetle) is a restoration priority in western North America be...

  8. Three Instruments in Four Years: The UCO/Lick Data-Driven Toolkit

    Science.gov (United States)

    Allen, S. L.; Clarke, D. A.

    A panoply of new software tools has accompanied the rapid instrument construction schedule at UCO/Lick Observatory (PFCAM to Lick in 1997, ESI to Keck in 1999, DEIMOS to Keck in 2000). These Tcl/Tk-based tools maintain and interact with a relational database of instrument characteristics. They assist software design, generate thousands of lines of code, documentation, and configuration files, facilitate motor-control calibration, permit fully-automated remote testing and evaluation of performance, aid user-interface design, produce diagrams, and serve as a communications nexus between software and hardware teams. The toolkit has greatly reduced the amount of effort required from many UCO/Lick technicians, and has set new standards for quality and performance of the resulting instruments. We present here an overview of these tools and their outputs.

  9. Examining Elementary Teachers' Engineering Self-Efficacy and Engineering Teacher Efficacy

    Science.gov (United States)

    Hammack, Rebekah; Ivey, Toni

    2017-01-01

    Research indicates that teacher efficacy influences student achievement and is situation specific. With the Next Generation Science Standards calling for the incorporation of engineering practices into K-12 classrooms, it is important to identify teachers' engineering teaching efficacy. A study of K-5 teachers' engineering self-efficacy and…

  10. Examining Elementary Teachers' Engineering Self-Efficacy and Engineering Teacher Efficacy

    Science.gov (United States)

    Hammack, Rebekah; Ivey, Toni

    2017-01-01

    Research indicates that teacher efficacy influences student achievement and is situation specific. With the Next Generation Science Standards calling for the incorporation of engineering practices into K-12 classrooms, it is important to identify teachers' engineering teaching efficacy. A study of K-5 teachers' engineering self-efficacy and…

  11. Principal Self-Efficacy and Work Engagement: Assessing a Norwegian Principal Self-Efficacy Scale

    Science.gov (United States)

    Federici, Roger A.; Skaalvik, Einar M.

    2011-01-01

    One purpose of the present study was to develop and test the factor structure of a multidimensional and hierarchical Norwegian Principal Self-Efficacy Scale (NPSES). Another purpose of the study was to investigate the relationship between principal self-efficacy and work engagement. Principal self-efficacy was measured by the 22-item NPSES. Work…

  12. The Relative Importance of Specific Self-Efficacy Sources in Pretraining Self-Efficacy Beliefs

    Science.gov (United States)

    Howardson, Garett N.; Behrend, Tara S.

    2015-01-01

    Self-efficacy is clearly important for learning. Research identifying the most important sources of self-efficacy beliefs, however, has been somewhat limited to date in that different disciplines focus largely on different sources of self-efficacy. Whereas education researchers focus on Bandura's original sources of "enactive mastery,"…

  13. Teachers' Sense of Efficacy: Examining the Relationship of Teacher Efficacy and Student Achievement

    Science.gov (United States)

    Alrefaei, Nouf

    The purpose of this study was to investigate which teachers' characteristics have an impact on teachers' sense of efficacy. In addition, the relationship between mathematics and science fifth grade teachers' sense of efficacy and student achievement was examined. Two characteristics related to teachers were examined: teachers' years of teaching experience and teachers' highest degree. Participants included 62 mathematics and science teachers from three school districts in Northwest Arkansas. When comparing fifth grade mathematics and science teachers' efficacy beliefs based on their highest degree, a significant difference in teachers' efficacy beliefs was found based on their degrees. Teachers with a Bachelor degree have higher total efficacy than teachers who hold Master's degrees. Moreover, an investigation to determine if there is a difference in mathematics and science teachers' efficacy beliefs in the three subscale of teachers' efficacy (for classroom management, for student engagement, and for instructional strategies) revealed a significant difference in teachers' efficacy for two of the three constructs. However, when examining teachers' sense of efficacy based on their teaching experience, no differences in teachers' efficacy were found. A correlation was conducted and the results indicated that there was no significant relationship between fifth grade teachers' sense of efficacy and students' achievement in the benchmark test in mathematics and science. The recommendations from this study should be used to inform other scholars and administrators of the importance of teachers' sense of efficacy in order to improve students' achievement gains.

  14. Examining the influence of other-efficacy and self-efficacy on personal performance.

    Science.gov (United States)

    Dunlop, William L; Beatty, Daniel J; Beauchamp, Mark R

    2011-08-01

    This research examined the relative effects of other-efficacy and self-efficacy beliefs in relation to individual performance within a cooperative dyadic setting. Pairs of female participants (M(age) = 20.08, SD = 1.93) performed three practice trials on a dyadic dance-based videogame. Other-efficacy and self-efficacy beliefs were then manipulated through the provision of bogus feedback regarding each pair member's coordination abilities. Following the administration of this feedback, pairs performed a final trial on this dance-based task. The results revealed a main effect for other-efficacy, such that participants in the enhanced other-efficacy conditions outperformed those in the inhibited other-efficacy conditions on this task. A main effect for self-efficacy was not observed. Furthermore, there was no evidence of an interaction between other-efficacy and self-efficacy. The results of this study suggest that other-efficacy may supersede the effects of self-efficacy in supporting personal performance within cooperative relational contexts.

  15. Examining Relationships among Elementary Mathematics Teachers' Efficacy and Their Students' Mathematics Self-Efficacy and Achievement

    Science.gov (United States)

    Chang, Yu-Liang

    2015-01-01

    The purpose of this study was to examine the effects of fifth-grade mathematics teachers' efficacy (MTE) on their students' mathematics self-efficacy (SMSE) and mathematical achievement (SMA) in classrooms. Two mathematics efficacy instruments were administered to 58 classes (i.e. 58 teachers and 1244 fifth-graders respectively) to gather data…

  16. Novice teachers’ classroom management self efficacy beliefs

    Directory of Open Access Journals (Sweden)

    Türkay Nuri Tok

    2016-12-01

    Full Text Available This study aims to determine novice teachers’ classrom management self efficacy beliefs as well as the extent to which these beliefs change according to independent variables. This research which aims to determine novice teachers’ classroom management self efficacy beliefs is a survey type research. The participants of the study are 85 novice teachers on duty in their first year in Hatay Province in Turkey. Classroom Management Self-Efficacy Convictions Scale that is internally consistent and valid in measuring classroom management self-efficacy beliefs of prospective teachers devised by Çetin (2013 was used in the study. There is not any statistically significant difference in terms of school of graduation and classroom management efficacy belief and result expectation sub-dimension. There is not any statistically significant difference in classroom management efficacy belief and result expectation sub-dimension. In terms of gender, there is not any statistically significant difference in the result expectation sub-dimension but there is a statistically significant difference in classroom management efficacy belief. Male novice teachers have higher level of classroom management efficacy beliefs than female novice teachers.

  17. Measuring Teacher Efficacy to Implement Inclusive Practices

    Science.gov (United States)

    Sharma, Umesh; Loreman, Tim; Forlin, Chris

    2012-01-01

    The purpose of this study was to develop an instrument to measure perceived teacher efficacy to teach in inclusive classrooms. An 18-item scale was developed on a sample of 607 pre-service teachers selected from four countries (Canada, Australia, Hong Kong and India). Factor analysis of responses from the sample revealed three factors: efficacy in…

  18. Development of Physics Self-Efficacy Scale

    Science.gov (United States)

    Çalişkan, Serap; Selçuk, Gamze S.; Erol, Mustafa

    2007-04-01

    In this article, we describe development of a Physics Self-Efficacy Scale (PSES) that is a self-administered measure to assess physics self-efficacy beliefs regarding one's ability to successfully perform physics tasks in physics classroom. The scale is initially composed of 56 items prepared following a brief scrutiny of relating literature on self-efficacy. It was initially administered 30 physics teacher candidates and was also examined by 6 experts of physics education, then ambiguous or incomprehensible 6 items were dismissed. This PSES was tested on 558 undergraduate students all completed fundamental physics courses. Cronbach's Alpha reliability coefficient of the PSES was calculated as 0.94. The final version of the PSES contained 30 items with 5 dimensions namely, 1. Self-efficacy towards solving physics problems, 2. Self-efficacy towards physics laboratory, 3. Self-efficacy towards learning physics, 4. Self-efficacy towards application of physics knowledge and 5. Self-efficacy towards memorizing physics knowledge.

  19. How specific is specific self-efficacy?

    DEFF Research Database (Denmark)

    Nielsen, Tine; Makransky, Guido; Vang, Maria Louison

    2017-01-01

    Self-efficacy is an important and much used construct in psychology and social science studies. The validity of the measurements used is not always sufficiently evaluated. The aim was to evaluate the psychometric properties of the Danish translation of the self-efficacy subscale of The Motivated...

  20. Impact of Teacher Preparation upon Teacher Efficacy

    Science.gov (United States)

    Redmon, Robert J.

    2007-01-01

    A cohort of students in a teacher preparation program completed questionnaires measuring their feelings of teacher self efficacy at three points in the program. Results suggest that pre-service teachers' feelings of self efficacy do improve as a result of their participation in such programs. (Contains 1 figure and 1 table. Teacher Efficacy…

  1. Preservice Teachers' Technology Self-Efficacy

    Science.gov (United States)

    Kent, Andrea M.; Giles, Rebecca M.

    2017-01-01

    Since efficacy of experienced teachers is difficult to change (Hoy, 2000), preservice teachers' technology self-efficacy is a creditable indicator of graduates' likelihood to use instructional technology throughout their careers. A study was conducted with elementary preservice teachers (n = 62) who completed a 5-item, Likert-type survey measuring…

  2. General Chemistry and Self-Efficacy.

    Science.gov (United States)

    Smist, Julianne M.

    Several researchers have argued that the underrepresentation of women and minorities in professional occupations results from negative beliefs or attitudes, particularly self-efficacy expectations. A Science Self-Efficacy Questionnaire (SSEQ) was designed and later administered to 430 students (all were enrolled in freshman general chemistry and…

  3. Lessons from HIV-1 vaccine efficacy trials.

    Science.gov (United States)

    Excler, Jean-Louis; Michael, Nelson L

    2016-11-01

    Only four HIV-1 vaccine concepts have been tested in six efficacy trials with no product licensed to date. Several scientific and programmatic lessons can be learned from these studies generating new hypotheses and guiding future steps. RV144 [ALVAC-HIV (canarypox vector) and AIDSVAX B/E (bivalent gp120 HIV-1 subtype B and CRF01_AE)] remains the only efficacy trial that demonstrated a modest vaccine efficacy, which led to the identification of immune correlates of risk. Progress on subtype-specific, ALVAC (canarypox vector) and gp120 vaccine prime-boost approaches has been slow, but we are finally close to the launch of an efficacy study in Africa in 2016. The quest of a globally effective HIV-1 vaccine has led to the development of new approaches. Efficacy studies of combinations of Adenovirus type 26 (Ad26)/Modified Vaccinia Ankara (MVA)/gp140 vaccines with mosaic designs will enter efficacy studies mid-2017 and cytomegalovirus (CMV)-vectored vaccines begin Phase I studies at the same time. Future HIV-1 vaccine efficacy trials face practical challenges as effective nonvaccine prevention programs are projected to decrease HIV-1 incidence. An HIV-1 vaccine is urgently needed. Increased industry involvement, mobilization of resources, expansion of a robust pipeline of new concepts, and robust preclinical challenge studies will be essential to accelerate efficacy testing of next generation HIV-1 vaccine candidates.

  4. Self-Efficacy for Creative Productivity.

    Science.gov (United States)

    Schack, Gina

    The Efficacy Scale for Creative Productivity (ESCreP) was developed to measure students' convictions that they could be creative producers. Self-efficacy, an individual's estimation of ability to perform a behavior, is based upon performance accomplishments, vicarious experiences, verbal persuasion, and emotional or physiological arousal. Three…

  5. Maximum Spectral Luminous Efficacy of White Light

    CERN Document Server

    Murphy, T W

    2013-01-01

    As lighting efficiency improves, it is useful to understand the theoretical limits to luminous efficacy for light that we perceive as white. Independent of the efficiency with which photons are generated, there exists a spectrally-imposed limit to the luminous efficacy of any source of photons. We find that, depending on the acceptable bandpass and---to a lesser extent---the color temperature of the light, the ideal white light source achieves a spectral luminous efficacy of 250--370 lm/W. This is consistent with previous calculations, but here we explore the maximum luminous efficacy as a function of photopic sensitivity threshold, color temperature, and color rendering index; deriving peak performance as a function of all three parameters. We also present example experimental spectra from a variety of light sources, quantifying the intrinsic efficacy of their spectral distributions.

  6. A importância do Serviço de Informações sobre Agentes Teratogênicos, Bahia, Brasil, na prevenção de malformações congênitas: análise dos quatro primeiros anos de funcionamento Importance of the Teratogen Information Service in Bahia, Brazil, for prevention of congenital malformations: an initial four-year review

    Directory of Open Access Journals (Sweden)

    Maria Betânia Toralles

    2009-01-01

    Full Text Available Agente teratogênico é definido como o agente físico, químico, biológico ou estado de deficiência que, durante a vida embrionária, leva a alteração na estrutura ou função do concepto. Informações sobre a conduta a ser tomada no caso de exposições a teratogênicos durante a gestação são imprescindíveis. Com essa finalidade, em 2001, foi implantado o Serviço de Informações sobre Agentes Teratogênicos da Bahia (SIAT-BA, localizado no Serviço de Genética Médica do Hospital Universitário Professor Edgard Santos da Universidade Federal da Bahia. O objetivo é descrever as características do atendimento do SIAT-BA nos seus primeiros quatro anos de funcionamento. As consultas foram realizadas através do contato via telefone, fax ou e-mail, entre março de 2001 e maio de 2005. Nesse período, o SIAT-BA recebeu 408 consultas, totalizando 1.091 motivos. A maioria das consultas foi realizada por gestantes e profissionais de saúde. Produtos para cabelo, chás e misoprostol foram os agentes mais investigados. O pequeno número de consultas (1/dia indica a necessidade de maior divulgação do serviço e da conscientização da população sobre os riscos oferecidos pelos diversos agentes.Teratogenic agents are defined as physical, chemical, or biological agents or nutrient deficiencies that lead to fetal structural or functional alterations. Information on the effects of exposure to teratogens during pregnancy is of the utmost importance. In order to achieve this goal, in 2001, the Bahia State Teratogen Information Service was created in the Medical Genetics Department at the University Hospital of the Federal University in Bahia. The current paper aimed to describe the first four years of operation in the service. From March 2001 to May 2005, the service was consulted by telephone, fax, and e-mail. During this period, 408 queries were made, for a total of 1,091 different reasons. Most queries were made by pregnant women and health

  7. Efficacy of intraoperative neurophysiological monitoring.

    Science.gov (United States)

    Fisher, R S; Raudzens, P; Nunemacher, M

    1995-01-01

    Intraoperative neurophysiological monitoring is of benefit in protecting tissue at risk for trauma or ischemia during surgical procedures. Monitoring modalities include EEG, computer processed EEG, somatosensory (SEP), auditory (BAEP), and visual evoked potentials (VEP), and cranial nerve monitoring. The efficacy of monitoring is controversial, because no properly controlled prospective study of outcome with and without monitoring has been done. The weight of evidence suggests that loss of spontaneous EEG and SEP correlate well with critical reductions of cerebral blood flow. Meta-analysis of series comprising 3,028 patients undergoing carotid endarterectomies shows that SEP deteriorated in 5.6% of cases, with 20% of these having postoperative deficits, but more might have had deficits if they had not been shunted. SEP monitoring can be useful in surgery affecting brain and cord vasculature. Monitoring is not indicated for routine lumbosacral spine surgery. BAEPs have predictive value for preservation of hearing after acoustic neuroma surgery, and other surgery near the brainstem. VEPs have been too variable to be of major use in the operating room. For neurophysiologic monitoring to be useful, it must be performed by an experienced team, and the surgeon must be willing to act on the findings. Under these circumstances, monitoring can reduce surgical complications in selected cases.

  8. At-Risk Boys' Social Self-Efficacy and Physical Activity Self-Efficacy in a Summer Sports Camp

    Science.gov (United States)

    Su, Xiaoxia; Xiang, Ping; McBride, Ron E.; Liu, Jiling; Thornton, Michael A.

    2016-01-01

    This study examined at-risk boys' social self-efficacy and physical activity self-efficacy within Bandura's self-efficacy framework. A total of 97 boys, aged between 10 and 13 years, attending a summer sports camp completed questionnaires assessing their social self-efficacy, physical activity self- efficacy, prosocial behaviors, and effort.…

  9. Examining Elementary School-Aged Children's Self-Efficacy and Proxy Efficacy for Fruit and Vegetable Consumption

    Science.gov (United States)

    Geller, Karly S.; Dzewaltowski, David A.

    2010-01-01

    Children's self-efficacy for fruit and vegetable consumption (FVC) and proxy efficacy to influence others to make fruit and vegetables (FV) available may influence their FVC. A previous investigation has demonstrated that self-efficacy for fruit consumption, self-efficacy for vegetable consumption, proxy efficacy to influence parents to make FV…

  10. Leadership, self-efficacy, and student achievement

    Science.gov (United States)

    Grayson, Kristin

    This study examined the relationships between teacher leadership, science teacher self-efficacy, and fifth-grade science student achievement in diverse schools in a San Antonio, Texas, metropolitan school district. Teachers completed a modified version of the Leadership Behavior Description Question (LBDQ) Form XII by Stogdill (1969), the Science Efficacy and Belief Expectations for Science Teaching (SEBEST) by Ritter, Boone, and Rubba (2001, January). Students' scores on the Texas Assessment of Knowledge and Skills (TAKS) measured fifth-grade science achievement. At the teacher level of analysis multiple regressions showed the following relationships between teachers' science self-efficacy and teacher classroom leadership behaviors and the various teacher and school demographic variables. Predictors of teacher self efficacy beliefs included teacher's level of education, gender, and leadership initiating structure. The only significant predictor of teacher self-efficacy outcome expectancy was gender. Higher teacher self-efficacy beliefs predicted higher leadership initiating structure. At the school level of analysis, higher school levels of percentage of students from low socio-economic backgrounds and higher percentage of limited English proficient students predicted lower school student mean science achievement. These findings suggest a need for continued research to clarify relationships between teacher classroom leadership, science teacher self-efficacy, and student achievement especially at the teacher level of analysis. Findings also indicate the importance of developing instructional methods to address student demographics and their needs so that all students, despite their backgrounds, will achieve in science.

  11. An Analysis on the Effect of Computer Self-Efficacy over Scientific Research Self-Efficacy and Information Literacy Self-Efficacy

    Science.gov (United States)

    Tuncer, Murat

    2013-01-01

    Present research investigates reciprocal relations amidst computer self-efficacy, scientific research and information literacy self-efficacy. Research findings have demonstrated that according to standardized regression coefficients, computer self-efficacy has a positive effect on information literacy self-efficacy. Likewise it has been detected…

  12. An Analysis on the Effect of Computer Self-Efficacy over Scientific Research Self-Efficacy and Information Literacy Self-Efficacy

    Science.gov (United States)

    Tuncer, Murat

    2013-01-01

    Present research investigates reciprocal relations amidst computer self-efficacy, scientific research and information literacy self-efficacy. Research findings have demonstrated that according to standardized regression coefficients, computer self-efficacy has a positive effect on information literacy self-efficacy. Likewise it has been detected…

  13. Thermal styling: efficacy, convenience, damage tradeoffs.

    Science.gov (United States)

    Harper, Don; Qi, Jia Catherine; Kaplan, Peter

    2011-01-01

    We introduce a simple method to explore the efficacy of thermal styling, By using a temperature gradient curling iron we rapidly explore a range of thermal treatment conditions. The thermodynamic literature on the glass transition in keratin fibers explains the surprisingly limited role of elevated temperature in improvements in the efficacy of holding the styled curvature of the fibers. The onset of damage, however, is strongly temperature dependent. This combination of measurements of damage and efficacy shows the range of conditions over which thermal protection products must be functional.

  14. Microbiota Influences Vaccine and Mucosal Adjuvant Efficacy

    Science.gov (United States)

    2017-01-01

    A symbiotic relationship between humans and the microbiota is critical for the maintenance of our health, including development of the immune system, enhancement of the epithelial barrier, and acquisition of nutrients. Recent research has shown that the microbiota impacts immune cell development and differentiation. These findings suggest that the microbiota may also influence adjuvant and vaccine efficacy. Indeed, several factors such as malnutrition and poor sanitation, which affect gut microbiota composition, impair the efficacy of vaccines. Although there is little evidence that microbiota alters vaccine efficacy, further understanding of human immune system-microbiota interactions may lead to the effective development of adjuvants and vaccines for the treatment of diseases. PMID:28261017

  15. Clinical efficacy of photodynamic therapy

    Science.gov (United States)

    Park, Ye-Kyu

    2016-01-01

    Objective The management of cervical intraepithelial neoplasia (CIN) and early invasive cancer of the uterine cervix is very difficult to approach, especially in case of young woman who wants to preserve her fertility. Conization of the cervix may have various kinds of disadvantage. The objective of this clinical retrospective study is to investigate the therapeutic effects and clinical efficacy of photodynamic therapy (PDT) including combined chemo-photodynamic therapy in patients with pre-malignant CIN and malignant invasive cervical cancer. Methods Total number of PDT trial case was 50 cases and total number of patient was 22 patients who registered to PDT clinic. We used photogem sensitizer and 632 nm diode laser in early two cases. After then we performed PDT using photofrin sensitizer and 630 nm diode laser in other cases. We used flat-cut, microlens, cylindrical diffuser, and interstitial type optic fibers in order to irradiate the lesions. 240 J/cm2 energy was irradiated to the lesions. Results CIN 2 were 4 cases (18.2%) and CIN 3 were 15 (68.2%) and invasive cervical cancer were 3 (13.6%). Complete remission (CR) was found in 20 patients (91%). One case of 19 patients with CIN lesion recurred at 18 months after PDT treatment. CR was found in 18 cases in the patients with CIN lesions (95%). CR was found in 2 cases in the patients with invasive cervical cancer (67%). Conclusion Our data showed that CR rate was fantastic in CIN group (95%). This study suggests that PDT can be recommended as new optimistic management modality on the patients with pre-malignant CIN lesions including carcinoma in situ and relatively early invasive cancer of the uterine cervix. Combined chemo-photodynamic therapy is essential in case of invasive cervical cancer. For the young age group who desperately want to preserve their fertility and have a healthy baby, PDT can be a beacon of hope. PMID:27896250

  16. Clinical efficacy of photodynamic therapy.

    Science.gov (United States)

    Park, Ye-Kyu; Park, Choong-Hak

    2016-11-01

    The management of cervical intraepithelial neoplasia (CIN) and early invasive cancer of the uterine cervix is very difficult to approach, especially in case of young woman who wants to preserve her fertility. Conization of the cervix may have various kinds of disadvantage. The objective of this clinical retrospective study is to investigate the therapeutic effects and clinical efficacy of photodynamic therapy (PDT) including combined chemo-photodynamic therapy in patients with pre-malignant CIN and malignant invasive cervical cancer. Total number of PDT trial case was 50 cases and total number of patient was 22 patients who registered to PDT clinic. We used photogem sensitizer and 632 nm diode laser in early two cases. After then we performed PDT using photofrin sensitizer and 630 nm diode laser in other cases. We used flat-cut, microlens, cylindrical diffuser, and interstitial type optic fibers in order to irradiate the lesions. 240 J/cm(2) energy was irradiated to the lesions. CIN 2 were 4 cases (18.2%) and CIN 3 were 15 (68.2%) and invasive cervical cancer were 3 (13.6%). Complete remission (CR) was found in 20 patients (91%). One case of 19 patients with CIN lesion recurred at 18 months after PDT treatment. CR was found in 18 cases in the patients with CIN lesions (95%). CR was found in 2 cases in the patients with invasive cervical cancer (67%). Our data showed that CR rate was fantastic in CIN group (95%). This study suggests that PDT can be recommended as new optimistic management modality on the patients with pre-malignant CIN lesions including carcinoma in situ and relatively early invasive cancer of the uterine cervix. Combined chemo-photodynamic therapy is essential in case of invasive cervical cancer. For the young age group who desperately want to preserve their fertility and have a healthy baby, PDT can be a beacon of hope.

  17. EFFICACY OF ANTIOXIDANTS IN HUMAN HEALTH | Waling ...

    African Journals Online (AJOL)

    EFFICACY OF ANTIOXIDANTS IN HUMAN HEALTH. ... African Journal of Food, Agriculture, Nutrition and Development ... add variety to household diets and nutrients, and improve household incomes for improved food security situation.

  18. Concurrent Anticonvulsant/Ketogenic Diet Efficacy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2009-09-01

    Full Text Available Researchers at the Johns Hopkins Hospital, Baltimore, studied retrospectively the comparative efficacy of six most frequently used anticonvulsants when employed in combination with the ketogenic diet (KD for treatment of 115 children with epilepsy.

  19. Efficacy of ibandronate: a long term confirmation.

    Science.gov (United States)

    Di Munno, Ombretta; Delle Sedie, Andrea

    2010-01-01

    Data deriving from randomized clinical trials, observational studies and meta-analyses, including treatment regimens unlicensed for use in clinical practice, clearly support that 150 mg once-monthly oral and 3 mg quarterly i.v. doses of ibandronate are associated with efficacy, safety and tolerability; notably both these marketed regimens, which largely correspond to ACE ≥10.8 mg, may in addition provide a significant efficacy on non-vertebral and clinical fracture (Fx) efficacy. The MOBILE and the DIVA LTE studies confirmed a sustained efficacy of monthly oral and quarterly i.v. regimens respectively, over 5 years. Furthermore, improved adherence rates with monthly ibandronate, deriving from studies evaluating large prescription databases, promise to enhance fracture protection and decrease the social and economic burden of postmenopausal osteoporosis.

  20. Adolescent Work Experience and Self-efficacy.

    Science.gov (United States)

    Cunnien, Keith A; Martinrogers, Nicole; Mortimer, Jeylan T

    2009-01-01

    PURPOSE OF THIS PAPER: To assess the relationship between high school work experiences and self-efficacy. DESIGN/METHODOLOGY/APPROACH: OLS regressions are applied to longitudinal data from the Youth Development Study to examine work experiences and self-efficacy. FINDINGS: The analyses indicate that employment fosters self-efficacy in multiple realms, Occasional and sporadic workers exhibit less self-efficacy than steady workers. Supervisory support may be especially important in enhancing adolescents' confidence as they anticipate their future family lives, community participation, personal health, and economic achievements. RESEARCH LIMITATIONS/IMPLICATIONS: This research includes only a small set of the work dimensions that may be important for adolescents. Ethnography and in-depth interviews are recommended to further explore the subjective and emotional dimensions of youth work experiences. PRACTICAL IMPLICATIONS: In developing policies and guidance, educators, parents, and employers should be aware that steady employment and supervisory support enhance the development of adolescent self-efficacy. ORIGINAL VALUE OF PAPER: This paper finds evidence that adolescent work experiences spill over to influence youth's developing confidence in the realms of family life, community and personal health. It also suggests that sporadic and occasional work patterns can impair the development of self-efficacy in adolescence.