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Sample records for fosdick mountains marie

  1. Are cumulate granites characteristic of migmatitic gneiss domes? An example from the Fosdick Mountains of Marie Byrd Land, West Antarctica

    Science.gov (United States)

    Brown, Caitlin R.; Yakymchuk, Chris; Brown, Michael; Fanning, C. Mark; Korhonen, Fawna J.; Piccoli, Philip M.; Siddoway, Christine S.

    2014-05-01

    , which was emplaced at higher structural levels outside the Fosdick complex. These granites yield U-Pb zircon crystallization ages of 105-102 Ma. They have elevated K2O contents relative to granites in the Fosdick complex and large negative Eu anomalies. Furthermore, their Sr and Nd whole-rock and Hf and O zircon isotope compositions are consistent with derivation from crystallizing granites within the Fosdick complex. These results contribute to a growing number of studies that suggest granites in migmatite-granite complexes are accumulations of residual and newly crystallized feldspar and quartz after melt drainage rather than primary or minimum-melt compositions. There are two important implications of cumulate granites in migmatite complexes. First, it demonstrates that melt crystallization began during melt migration and emplacement. As a result, it is possible that cumulate minerals in melt transport conduits may restrict the flow of melt or could locally clog the anatectic plumbing system. This possibility may need to be considered as a rate-limiting step in studies that examine the timescales of melt extraction from the deep crust. Second, the drained melt will have evolved compositions with higher concentrations of the heat producing elements. This has important implications for the tectonic history of large hot mountain belts, cooling ultrahigh-temperature (UHT) metamorphic terrains, priming the crust for future UHT metamorphic events and the long-term stability of the continental crust.

  2. Marie Curie; Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Trotereau, J.

    2011-07-01

    The legend has only retained from Marie Curie (1867-1934) the image of a hard and brilliant worker, pioneer in the radioactivity domain, and who awarded twice the Nobel Price. Behind the scientist, there is a women, Marya Salomea Sklodowska, the 'Polish', who was considered during some time as an 'alien', an 'atheistic intellectual', an 'emancipated women'. When she died alone in July 1934, after an exhausting life of labour, her funeral led to no official ceremony or speech. This small book summarizes the biography of the most famous female scientist in the world

  3. Marie Curie

    National Research Council Canada - National Science Library

    Serna M., Edgar

    2011-01-01

    Maria Sklodowska--Marie Curie--fue pionera en la ciencia de la radiactividad; es mejor conocida como la descubridora de los elementos radiactivos polonio y radio, y como el primer cientifico en ganar dos premios Nobel: Fisica y Quimica...

  4. Late Holocene Deglaciation of Marie Byrd Land, West Antarctica

    Science.gov (United States)

    Stone, J. O.; Balco, G.; Sugden, D. E.; Caffee, M.; Siddoway, C.; Sass, L.; Cowdery, S.

    2001-12-01

    The deglaciation history of West Antarctica provides a long-term record of West Antarctic ice sheet dynamics on timescales that are difficult to address observationally or by modeling. By dating moraine deposits stranded on mountain flanks as the ice sheet thinned, we are reconstructing the deglaciation history of a 70 km transect along the Boyd Glacier, in the Ford Ranges, Marie Byrd Land. Fresh erratics and abraded bedrock extend to summit level on most nunataks, indicating that these were overrun by ice during the last glaciation. Conversely, high summits near the coast are more intensely weathered than lower-lying peaks, and one erratic from this weathered zone gives a cosmogenic Be-10 exposure age of 103 ka, suggesting (though it does not prove) that these peaks stood above the surface of the glacial maximum ice sheet. If so, the age of an erratic immediately below the weathering boundary, 10.4 +/- 0.7 ka, dates the glacial maximum in the Ford Ranges. All other erratics, from glaciated surfaces at lower elevation, give younger exposure ages. Summit erratics from Mt Blades, Mt Passel and an unnamed nunatak in the eastern Fosdick Mtns indicate that these peaks emerged from the ice sheet at 6.8 +/- 0.5 ka, 3.6 +/- 0.3 ka, and 4.7 +/- 0.4 ka, respectively. Subsequent downwasting rates, inferred from the decrease in exposure ages with elevation on these mountains, were between 5 and 10 cm per year. The youngest age obtained so far, 590 +/- 70 years, comes from an erratic on the lower slopes of Mt Rea, 100-150 m above the Arthur and Boyd Glaciers. From these results we can draw the following conclusions about West Antarctic Ice Sheet (WAIS) deglaciation in the Ford Ranges: (i) Most thinning of the WAIS took place in the late Holocene. (ii) Therefore, recession post-dated climatic warming, which Antarctic ice cores indicate commenced at 20 ka, by 10-15 kyr. (iii) Recession post-dated all but the final stages of global eustatic sea level rise. The ice sheet grounding

  5. Mountaineering

    Institute of Scientific and Technical Information of China (English)

    潘步东

    2005-01-01

    Most young people enjoy some forms of physical activities.It may be walking,cycling or swimming,or in wither,skating or skiing.It may be a game of some kind,football,hockey(曲棍球),golf,or tennis.Perhaps it may be mountaineering.

  6. Proposal for the pre-sediment removal aquatic survey of Lake Mary, Ladora, and Lower Derby Reservois located on the U.S. Army Rocky Mountain Arsenal, Colorado

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Proposal for a monitoring program at the Rocky Mountain Arsenal (RMA) to document the effectiveness of the sediment removal program. This project has been initiated...

  7. MARIE CURIE

    Directory of Open Access Journals (Sweden)

    EDGAR SERNA MONTOYA

    2011-12-01

    Full Text Available María Sklodowska ‒Marie Curie‒ fue pionera en la ciencia de la radiactividad; es mejor conocida como la descubridora de los elementos radiactivos polonio y radio, y como el primer científico en ganar dos premios Nobel: Física y Química. Para sus colegas y el público en general, el radio fue la clave para un cambio fundamental en nuestra comprensión de la materia y la energía. Su trabajo no sólo influyó en el desarrollo de la ciencia fundamental, sino que también marcó el comienzo de una nueva era en la investigación y los tratamientos médicos.

  8. Kaks Mari Vaalas / Eha Komissarov

    Index Scriptorium Estoniae

    Komissarov, Eha, 1947-

    1999-01-01

    9. nov.-st galeriis 'Vaal' Mari Roosvaldi maalinäitus 'Persoon'; 10. nov.-st galerii keldrisaalis Mari Kurismaa 'Matemaatika ja metafüüsika'. Mari Roosvaldi kollaazhides on ühendatud maal ja foto.

  9. Kaks Mari Vaalas / Eha Komissarov

    Index Scriptorium Estoniae

    Komissarov, Eha, 1947-

    1999-01-01

    9. nov.-st galeriis 'Vaal' Mari Roosvaldi maalinäitus 'Persoon'; 10. nov.-st galerii keldrisaalis Mari Kurismaa 'Matemaatika ja metafüüsika'. Mari Roosvaldi kollaazhides on ühendatud maal ja foto.

  10. Avangardistid Moskvas / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Valdek Alberi ja Taave Tuutma videoinstallatsioonist "Think different" näitusel "Salon 2000" Moskva Kunstnike Keskmajas 16.-26. III. Kuraator Mari Sobolev. Eesti väljapaneku vastukajast ja Jüri Arrakust, kelle maalid olid näitusel "Balti meistrid", ajalehes "Kommersant". Moskva kunstinäitustest.

  11. Avangardistid Moskvas / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Valdek Alberi ja Taave Tuutma videoinstallatsioonist "Think different" näitusel "Salon 2000" Moskva Kunstnike Keskmajas 16.-26. III. Kuraator Mari Sobolev. Eesti väljapaneku vastukajast ja Jüri Arrakust, kelle maalid olid näitusel "Balti meistrid", ajalehes "Kommersant". Moskva kunstinäitustest.

  12. MARI mini-manual

    Science.gov (United States)

    Bennington, S. M.; Eccleston, R. S.

    1994-09-01

    The MARI spectrometer is funded by the Japanese Ministry of Education, Culture and Science (Monbusho) as part of the UK-Japan collaboration in neutron scattering. MARI is a direct geometry chopper spectrometer. It uses a Fermi chopper to monochromatic the incident neutron beam to give incident energies in the range 10 to 2000 meV. It is very similar in design to its sister machine HET, but with a detector bank that continuously covers the angular range from 3 to 135 degrees, MARI is able to map large regions of Q-E space in a single measurement. At present about 600 of the full complement of 1000 detectors are installed. All are 10 bar (3)He gas proportional counters and all come from the same manufacturer, this means that their efficiency and background are almost the same. The beam size at the sample position is 50 by 50 mm, but motorized jaws in the Fermi chopper pit and in the sample tank can be used to reduce this size. Chapter headings are the following: Introduction; The hardware on MARI; Controlling the Instrument; Data Analysis and Visualization; Appendices.

  13. Klassika & ekskremendid / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2002-01-01

    20.-21. aprillil toimus Pärnus 8. Fideo- ja Vilmifestival alapealkirjaga "Eksperimendid ja klassika". Peakorraldaja Rael Artel. Rami Raski filmist "Legowitz 1999" (soome rühmitus Vivid), läti filmist "Love, death & television", Concordia ülikooli ("Ülemus") ja Academia Grata (portreefilmid Asta Isakist, Andrus Joonasest jm.) programmist, Kadriann Kibuse ja Liina Paakspuu filmist "Urban Obsessions", Mirja-Mari Smidti ja Allan Tõnissoo videost, Marianne Männi koomiksitest kataloogis

  14. Klassika & ekskremendid / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2002-01-01

    20.-21. aprillil toimus Pärnus 8. Fideo- ja Vilmifestival alapealkirjaga "Eksperimendid ja klassika". Peakorraldaja Rael Artel. Rami Raski filmist "Legowitz 1999" (soome rühmitus Vivid), läti filmist "Love, death & television", Concordia ülikooli ("Ülemus") ja Academia Grata (portreefilmid Asta Isakist, Andrus Joonasest jm.) programmist, Kadriann Kibuse ja Liina Paakspuu filmist "Urban Obsessions", Mirja-Mari Smidti ja Allan Tõnissoo videost, Marianne Männi koomiksitest kataloogis

  15. AN ELECTRICAL HAIL MARY.

    Science.gov (United States)

    Neubert, David

    2016-05-01

    Double sequential defibrillation is currently being employed in a number of EMS systems across the United States, including Wake County, N.C.; Fort Worth, Texas; and New Orleans. Even though there isn't a large body of literature surrounding this technique, it's been demonstrated successful in the electrophysiology lab, ED and prehospital settings. Since access to procainamide--another treatment for refractory v fib--is limited, this may be the only available option when faced with a patient who's failed standard ACLS defibrillation and medication administration. It's an intervention that has little chance to do harm, and it may represent the "hail Mary" pass to a successful ROSC touchdown.

  16. Mary, dogma, and psychoanalysis.

    Science.gov (United States)

    Todd, E H

    1985-06-01

    Why does Mary hold her prominent place in Catholic theology to the extent that five specific dogmas have developed around her? Psychoanalytic theory suggests dogma arises out of the psychic needs of people and psychic needs of people are expressed in dogma. The early views of Erich Fromm, a disciple of Freud, are presented to demonstrate that Marian dogma arose from the psychic needs of the people. The views of both Catholic and Protestant thinkers are presented, as well as theological and psychiatric views.

  17. On Source of Mary's Tragedy

    Institute of Scientific and Technical Information of China (English)

    胡杰

    2016-01-01

    Long Day's Journey into Night is a great work of American dramatist Eugene O'Neill. As the only female protagonist fully portrayed in the play, Mary's tragedy generated a hot debate. In this thesis, through detailed analysis, it is found that Mary is the victim of male-dominated society and men are the source of her tragedy.

  18. Robotic Software Integration Using MARIE

    Directory of Open Access Journals (Sweden)

    Dominic Letourneau Clement Raievsky

    2008-11-01

    Full Text Available This paper presents MARIE, a middleware framework oriented towards developing and integrating new and existing software for robotic systems. By using a generic communication framework, MARIE aims to create a flexible distributed component system that allows robotics developers to share software programs and algorithms, and design prototypes rapidly based on their own integration needs. The use of MARIE is illustrated with the design of a socially interactive autonomous mobile robot platform capable of map building, localization, navigation, tasks scheduling, sound source localization, tracking and separation, speech recognition and generation, visual tracking, message reading and graphical interaction using a touch screen interface.

  19. Robotic Software Integration Using MARIE

    Directory of Open Access Journals (Sweden)

    Carle Côté

    2006-03-01

    Full Text Available This paper presents MARIE, a middleware framework oriented towards developing and integrating new and existing software for robotic systems. By using a generic communication framework, MARIE aims to create a flexible distributed component system that allows robotics developers to share software programs and algorithms, and design prototypes rapidly based on their own integration needs. The use of MARIE is illustrated with the design of a socially interactive autonomous mobile robot platform capable of map building, localization, navigation, tasks scheduling, sound source localization, tracking and separation, speech recognition and generation, visual tracking, message reading and graphical interaction using a touch screen interface.

  20. Victor Hugo, Marie Tudor

    OpenAIRE

    Sabourin, Lise

    2016-01-01

    Dans la collection de poche qui rend aisément accessibles les grandes pièces du répertoire français, Clélia Anfray donne, avec une introduction (pp. 7-42), une notice sur la genèse, la rédaction et la parution, un historique des représentations, une chronologie, des indications bibliographiques et des notes, le texte du drame consacré par Hugo à cette «reine qui soit une femme. Grande comme une reine, vraie comme une femme» qu’il veut voir en Marie Tudor («Préface», p. 47). La documentation h...

  1. Multistate Aquatic Resources Information System (MARIS)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — MARIS is an internet-based information sharing network that allows multiple states to provide a common set of variables via a single web interface. MARIS is not a...

  2. Mary Shelley: Teaching and Learning through "Frankenstein"

    Science.gov (United States)

    Girard, Theresa M.

    2009-01-01

    In the writing of "Frankenstein", Mary Shelley was able to change the course of women's learning, forever. Her life started from an elite standpoint as the child of Mary Wollstonecraft and William Godwin. As such, she was destined to grow to be a major influence in the world. Mary Shelley's formative years were spent with her father and his many…

  3. Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Reilly, Mary M

    2011-03-01

    Charcot-Marie-Tooth (CMT) disease is the commonest inherited neuromuscular disorder affecting at least 1 in 2,500. Over the last two decades, there have been rapid advances in understanding the molecular basis for many forms of CMT with more than 30 causative genes now described. This has made obtaining an accurate genetic diagnosis possible but at times challenging for clinicians. This review aims to provide a simple, pragmatic approach to diagnosing CMT from a clinician\\'s perspective.

  4. Mary Rudenberg, Music Therapist Pioneer

    Directory of Open Access Journals (Sweden)

    Christine Neugebauer

    2010-03-01

    Full Text Available It was during my training when I came to understand and appreciate the knowledge base and experience that Mary Rudenberg has contributed to the field of music therapy. Medical music therapy was still in its infancy and the music therapy internship program at the University of Texas Medical Branch in Galveston, Texas was one of a few internships in the nation offering music therapy training in a medical setting.

  5. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Rotermanni soolaladu. "Elektrokardiogramm" (tegevuskunsti üritus); Vaal-galerii. Antoni T̉pies "Litograafiaid aastatest 1973-1995"; Mari Kadanik, Eero Barndõk, Rain Ader "Pildid" (maalid); Paldiski Põhikool. "Niemenlautta ja Hugo Simbergi fotod" (soome kunstniku fotode koopiad, pildistatud enne 1915. a.; Kullo lastegalerii. Neli uut näitust.(lastekunst); Arhitektuurimuuseum. Arnold Matteus - Tartu linna arhitekt (juubelinäitus), Alvar Aalto "Kolm objekti Eestis"; Linnagalerii Tallinnas. "Valge" (ruumi- ja moekunsti näitus); Sammas-galerii. Jüri Jegorow "Insect" (arvutigraafika); Endla Teatri palmisaal. "Muzik in der Kunst" (Tallinna kunstitudengite näitus); Eesti Rahvusraamatukogu. Õie Kütt "Uued ja vanad ehted"

  6. [Review] Mary Toft's Rabbit Tale

    OpenAIRE

    Jones, Emrys

    2013-01-01

    Originally broadcast in April 2011 and aired again by BBC Radio 4 this November, Mary Toft’s Rabbit Tale is a radio drama retelling the story of its titular fraudster’s brief notoriety. With a high-profile cast – including singer Will Young as Toft’s husband and Rupert Graves as man-midwife, John Howard – the play explores a number of issues related to the alleged rabbit births of 1726 and their impact on public discourse of the time.

  7. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Rotermanni soolaladu. "Elektrokardiogramm" (tegevuskunsti üritus); Vaal-galerii. Antoni T̉pies "Litograafiaid aastatest 1973-1995"; Mari Kadanik, Eero Barndõk, Rain Ader "Pildid" (maalid); Paldiski Põhikool. "Niemenlautta ja Hugo Simbergi fotod" (soome kunstniku fotode koopiad, pildistatud enne 1915. a.; Kullo lastegalerii. Neli uut näitust.(lastekunst); Arhitektuurimuuseum. Arnold Matteus - Tartu linna arhitekt (juubelinäitus), Alvar Aalto "Kolm objekti Eestis"; Linnagalerii Tallinnas. "Valge" (ruumi- ja moekunsti näitus); Sammas-galerii. Jüri Jegorow "Insect" (arvutigraafika); Endla Teatri palmisaal. "Muzik in der Kunst" (Tallinna kunstitudengite näitus); Eesti Rahvusraamatukogu. Õie Kütt "Uued ja vanad ehted"

  8. Scheuthauer-Marie-Sainton syndrome

    Directory of Open Access Journals (Sweden)

    Vikas Elias Kuruvila

    2012-01-01

    Full Text Available Scheuthauer-Marie-Sainton syndrome also known as Cleidocranial dysplasia (CCD is an autosomal dominant disorder characteristically presented with multiple supernumerary teeth; partial or complete absence of the clavicles; and open sagittal sutures and fontanelles. This condition was first reported by Meckel in 1760. There is also evidence that it existed in the prehistoric man. More than 1,000 cases have been reported in the medical literature regarding this syndrome. A case of a 35-year-male of CCD with multiple supernumerary teeth is being reported. The diagnostic and management aspects of this syndrome are discussed.

  9. Colour Symbols in Mari Songs

    Directory of Open Access Journals (Sweden)

    Natalia Glukhova

    2016-06-01

    Full Text Available This article presents a system of colour symbols in Mari folk songs based on the results of a multifold investigation. The research was carried out with the help of a complex technique applied to 2100 songs from different song collections. Mari colour symbols have never before been the object of research. The process of investigation included several steps. The most important of these was the semantic analysis that helped to discern 2000 mentions of four main spectre colours as well as white, black, silver, and golden. Quantitative data evaluation singled out a dominant group by a dichotomous method, applying the principle of simple majority employed in mathematical statistics. The same technique divided the other colour symbols into complementary, auxiliary, and insignificant groups. The results of an investigation into ethnic symbology are also shown graphically. The main reconstructed meanings of colour in the analysed songs denote such emotions as joy, wonder, astonishment, grief, melancholy, some aesthetic ideals, ethical vices, as well as people’s character and appearance.

  10. Mary Priestley interviewed by Leslie Bunt

    Directory of Open Access Journals (Sweden)

    Leslie Bunt

    2004-07-01

    Full Text Available I interviewed Mary Priestley at her London flat in May 2004. Mary is a well-known figure throughout the world of music therapy. At the Ninth World Congress, held in Washington in 1999, her work in Analytical Music Therapy was celebrated as one of the five universally acknowledged approaches in music therapy. Before training as a music therapist Mary also worked as a writer, artist, illustrator and secretary. Born in 1925, she was the daughter of the English playwright and author J.B. Priestley and Jane Lewis who became his second wife.

  11. Digitization of the Mary Hamilton Papers

    Directory of Open Access Journals (Sweden)

    Gardner Anne-Christine

    2017-03-01

    Full Text Available Held at The John Rylands Library, Manchester, the Mary Hamilton Papers are a valuable, but still largely untapped resource for linguistic, cultural and literary studies focussing on the late eighteenth century. In her diaries Lady Mary Hamilton (1756-1816 documents daily life and friendships with intellectual figures of the time, for instance Horace Walpole and members of the Bluestocking circle, which included Elizabeth Montagu and Frances Burney. The archive also contains letters written to Lady Mary Hamilton by her family and other members of her social network.

  12. Jean-Marie Dufour 1937-2007

    CERN Multimedia

    2007-01-01

    Jean-Marie Dufour, who was head of the CERN Legal Service from 1974 until his retirement in 2001, passed away on 8 July. Following his arrival at CERN in 1966 during the crucial phase of expansion of the Laboratory’s site, Jean-Marie Dufour ensured that CERN’s rules were applied while taking part in essential stages of the Organization’s development. With his fine mind and erudition, Jean-Marie Dufour, a staunch European devoted to the CERN cause, has left his mark on the Legal Service. The Service will publish a tribute to him in a forthcoming issue of the Bulletin.

  13. Marie Curie during ORT4

    Science.gov (United States)

    2003-01-01

    Marie Curie rover drives down the rear ramp during Operational Readiness Test (ORT) 4.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  14. Marie Curie during ORT6

    Science.gov (United States)

    2003-01-01

    Marie Curie sits on the lander petal prior to deployment during the pre launch Operations Readiness Test (ORT) 6.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  15. Radium, Marie Curie and modern science.

    Science.gov (United States)

    Langevin-Joliot, H

    1998-11-01

    In 1898, the discovery of two new elements, polonium and radium, reawakened interest in the topic of uranic rays discovered 2 years before by H. Becquerel. Radioactivity, a name coined by Marie Curie, became a major research field for decades. The contrasting personalities of Pierre Curie, already a first-rank physicist, and of the young Marie Curie-Sklodowska as they undertook their common work are described. It is shown how a well-chosen quantitative method and a systematic approach combining physics and chemistry led to the discovery within less than 1 year. The special role of radium and the determination of its atomic weight by Marie Curie followed by her long-term program for accumulating pure radium salts are emphasized. The first woman with a full professorship at a French University, Marie Curie created and managed the Radium Institute.

  16. Radikaalsus muuseumi kaitsva teki all / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Rotermanni soolalaos avatud Marco (Marko) Laimre isiknäituse "Küsimused ja vastused" puhul 13. IV toimunud konverentsist. Johannes Saare, Eha Komissarovi, Hanno Soansi, Anders Härmi ja Mari Sobolevi ettekannetest

  17. Mari e-raamatukogu / Tatjana Verina ; vene keelest tõlkinud Ene Riet

    Index Scriptorium Estoniae

    Verina, Tatjana

    2011-01-01

    Mari e-raamatukogu loomise aluseks on Mari-Eli Vabariigi etnokultuuriliste ja rahvusvaheliste suhete arendamise projekt, hetkel on elektroonilises raamatukogus 52 täistekstilist teavikut Tšavaini nimelise Mari Rahvusraamatukogu haruldaste raamatute kogust

  18. Mari e-raamatukogu / Tatjana Verina ; vene keelest tõlkinud Ene Riet

    Index Scriptorium Estoniae

    Verina, Tatjana

    2011-01-01

    Mari e-raamatukogu loomise aluseks on Mari-Eli Vabariigi etnokultuuriliste ja rahvusvaheliste suhete arendamise projekt, hetkel on elektroonilises raamatukogus 52 täistekstilist teavikut Tšavaini nimelise Mari Rahvusraamatukogu haruldaste raamatute kogust

  19. CHARCOT-MARIE-TOOTH DISEASE

    Directory of Open Access Journals (Sweden)

    Lea Leonardis

    2003-09-01

    Full Text Available Background. Charcot-Marie-Tooth (CMT disease is a common inherited disorder of the peripheral nervous system. In our paper, different types of CMT are described with their typical clinical pictures, electrophysiological signs and molecular genetic studies. CMT is classified as demyelinative and axonal type and distal motor neuronopathy.Conclusions. CMT can be of autosomal dominant, recessive and X-linked inheritance. The most frequent form of CMT is the result of the dominantly inherited duplication of chromosome 17p11.2 and is marked as CMT1A. The same group involves also rare patients with point mutation in the peripheral myelin protein-22 gene. CMT1B is associated with point mutations in protein zero gene. CMT1C is linked to chromosome 16p13.1–12.3. Patients with point mutations in early growth response 2 gene (EGR2 are included in group CMT1D. The disease can be also inhereted X-linked (CMTX with the mutations in connexin-32 gene. In autosomal recessive inherited demyelinating polyneuropathies (CMT4, mutations are found in the myotubularin-related protein-2 (CMT4B, N-myc downstream-regulated gene 1 (CMT4D, EGR2 (CMT4E, and in the periaksin (CMT4F genes. In axonal inherited neuropathy, mutations are found in KIF1beta (CMT2A and in light neurofilament (CMT2E genes, other forms map to different chromosomal loci (CMT2B, CMT2D, CMT2F. Some suggestions for the diagnostic procedures of patients with CMT are given.

  20. Engineering international relations / Maris Riekstins ; interv. Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Riekstins, Maris

    2008-01-01

    Läti annab peatselt Läänemeremaade Nõukogu eesistuja teatepulga üle Taanile. Läti välisminister Maris Riekstins Läänemeremaade Nõukogu teemadest ning suhetest Venemaaga. Maris Riekstins'i CV

  1. Engineering international relations / Maris Riekstins ; interv. Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Riekstins, Maris

    2008-01-01

    Läti annab peatselt Läänemeremaade Nõukogu eesistuja teatepulga üle Taanile. Läti välisminister Maris Riekstins Läänemeremaade Nõukogu teemadest ning suhetest Venemaaga. Maris Riekstins'i CV

  2. Meet EPA Scientist Marie O'Shea, Ph.D.

    Science.gov (United States)

    EPA Scientist Dr. Marie O'Shea is Region 2's Liaison to the Agency's Office of Research and Development (ORD). Marie has a background in research on urban watershed management, focused on characterizing and controlling nutrients in stormwater runoff.

  3. MOUNTAINS UNITE

    Directory of Open Access Journals (Sweden)

    Svitlana Dovbenko

    2015-04-01

    Full Text Available Schools in the Ukrainian Carpathian mountain region work in specific conditions. They have original traditions, a special nature of learning and work. Indeed, because of a remote location mountain village school becomes the center for a cultural and spiritual life. Of course, it is related to a present social and economic situation in the country and a slow progress of society. Therefore, we need to look at mountain school with a broader angle, help it in comprehensive development of an individual and ensure an availability of quality education for children living in mountainous areas. Here we should talk about learning as well as laying the foundations for a life success. The international research project Mountain School. Status. Problems. Prospects for Development. Is established to help solve these problems. Precarpathian National University is an active member of the project.

  4. Precise and Efficient Retrieval of Captioned Images: The MARIE Project.

    Science.gov (United States)

    Rowe, Neil C.

    1999-01-01

    The MARIE project explores knowledge-based information retrieval of captioned images of the kind found in picture libraries and on the Internet. MARIE's five-part approach exploits the idea that images are easier to understand with context, especially descriptive text near them, but it also does image analysis. Experiments show MARIE prototypes…

  5. Mary Shelly and Her "Hideous Progeny"

    Institute of Scientific and Technical Information of China (English)

    谌英

    2011-01-01

    Mary Shelly's representative work Frankenstein has spawned innumerable interpretations since its first publication in 1818.This thesis explores Mary Shelly's motivation of creating the monster.Mary Shelly's "hideous progeny" to some degree is her "shadow"

  6. MaRIE Undulator & XFEL Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

    2015-03-23

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  7. Mountaineering Tourism

    Directory of Open Access Journals (Sweden)

    Patrick Maher

    2016-08-01

    Full Text Available Reviewed: Mountaineering Tourism Edited by Ghazali Musa, James Higham, and Anna Thompson-Carr. Abingdon, United Kingdom: Routledge, 2015. xxvi + 358 pp. Hardcover. US$ 145.00. ISBN 978-1-138-78237-2.

  8. Classroom Instruction: The Influences of Marie Clay

    Science.gov (United States)

    McNaughton, Stuart

    2014-01-01

    Marie Clay's body of work has influenced classroom instruction in direct and indirect ways, through large overarching themes in our pedagogical content knowledge as well as specific smart practices. This paper focuses on her the contributions to our thinking about instruction which come from two broad theoretical concepts; emergent literacy…

  9. Visions of Mary Wollstonecraft: Implications for Education.

    Science.gov (United States)

    Manus, Alice L.

    This paper discusses the educational and social philosophy of Mary Wollstonecraft, an English writer of the 18th century. Her works included "Vindication of the Rights of Man," and her best know work, "Vindication of the Rights of Woman" which was published in 1792 and consisted of the first sustained argument for female…

  10. Early Onset Charcot-Marie-Tooth Disease

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-06-01

    Full Text Available The clinical signs and genetic analysis of early-onset Charcot-Marie-Tooth disease (CMT in a 2-year-old boy and members of his family are reported from the Academic Medical Center, Amsterdam, and Sophia Children’s Hospital, Rotterdam, the Netherlands.

  11. Mari Trentinjan : Muzhtshina jejo smerti / Bernard Lavillier

    Index Scriptorium Estoniae

    Lavillier, Bernard

    2003-01-01

    Prantsuse näitlejanna Marie Trintignant'iga (41) suri 1. augustil Prantsusmaal oma elukaaslase, ansambli "Noir Desire" liidri Bertrand Cantat' poolt Vilniuses talle tekitatud trauma tagajärjel. Näitlejanna eludraama. Järgneb 5. jaan. 2004, lk. 16-18 : ill

  12. Bon appetite! / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis

    2009-01-01

    Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

  13. Mary Elizabeth Hickox Mandels, 90, bioenergy leader

    Directory of Open Access Journals (Sweden)

    Eveleigh Douglas E

    2009-09-01

    Full Text Available Abstract Mary E H Mandels, who spearheaded the US Army's national bioconversion studies for four decades and was an early proponent of conversion of waste biomass to readily bioconvertible sugars for the production of chemicals and transportation fuels such as ethanol, died 17 February 2008 at Natick, MA, USA. She was 90.

  14. Bon appetite! / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis

    2009-01-01

    Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

  15. Successful Female Mountaineers

    Institute of Scientific and Technical Information of China (English)

    TANSIYIN

    2004-01-01

    The Third Mountaineering Meet took place from September 26 to October 8, 2003. It was sponsored by the Tibet Association for Mountaineers and undertaken by the Tibet Mountaineering Team and the Tibet Mountaineering School.

  16. Mary Somerville and the world of science

    CERN Document Server

    Chapman, Allan

    2015-01-01

    Mary Somerville (1780-1872), after whom Somerville College Oxford was named, was the first woman scientist to win an international reputation entirely in her own right, rather than through association with a scientific brother or father. She was active in astronomy, one of the most demanding areas of science of the day, and flourished in the unique British tradition of Grand Amateurs, who paid their own way and were not affiliated with any academic institution. Mary Somerville was to science what Jane Austen was to literature and Frances Trollope to travel writing. Allan Chapman’s vivid account brings to light the story of an exceptional woman, whose achievements in a field dominated by men deserve to be very widely known.

  17. Jean-Marie Dufour 1937-2007

    CERN Multimedia

    2007-01-01

    Picture taken by Rudiger Voss in the Legal Service LibraryJean-Marie Dufour, CERN Legal Advisor from 1974 until his retirement in 2001, passed away on 8 July. For us, his colleagues in the Legal Service, Jean-Marie was a tutor and a reference, who passed on to us his passion for the practice of law in an intergovernmental organisation. As a boss, his abiding managerial quality was his unstinting loyalty to his collaborators. Jean-Marie joined CERN in 1966 and for the next 35 years was to be the guardian of the Laboratory’s rules. This was his view of the Organization: "...I have discovered [at CERN] a fascinating universe driven by two forces: science and Europe; a world of physicists and engineers who, encouraged by the States of Europe, run a remarkable Laboratory, where Europeans have achieved reconciliation and restored the grand tradition of European physics, attracting physicists from around the world; a Laboratory that transcends not only the fro...

  18. Women who Worked with Marie Curie.

    Science.gov (United States)

    Pigeard-Micault, Natalie

    2015-06-01

    Marie Curie directed a research laboratory for 28 years. Between 1906 and 1934, forty five women worked under her guidance. Some were, and are, well-known in their own countries as their first woman full professor such as Ellen Gleditsch or Margaret von Wrangel, but for twenty eight of them, who were often French, nothing has ever been written. The strong presence of women in Marie Curie's laboratory has often been highlighted and has been considered as an exception, and the result of deliberate choice. Of course, these women did not choose this workplace by accident. They knew its director was a woman, a laureate of one, and after 1911, two Nobel Prizes, who was leading a well-equipped laboratory with an important radioactive source. But how did Marie Curie selected her collaborators among the many applications she received? Was her choice influenced by gender? A prosopographical research based on genealogical researches and new sources explains this presence contextually and sheds light on several questions : where did these women come from, what were their social and geographic origins, did they occupy any specific cultural or technical area inside Curie's lab, what future did they have after the laboratory? Through their lives, we can question the existence, or not, of a one profile of the female researcher in scientific areas in France.

  19. Mary Katrantzou 真实之美

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    3月27日,Mary Katrantzou时装发布会将在751D·PARK第一车间举行。Mary Katrantzou的主题发布围绕奢华的代名词展开,意在寻找过滤奢华之后的美丽;一件源于艺术或设计的作品如果过于真实,女性是无法穿戴的。前几季主要基于香水瓶,艺术内饰和的艺术实体,例如花田,日常物品,古董邮票,风景的设计系列以及最近的鞋子系列,均以印花图案为其审美核心。Mary Katrantzou在伦敦时装周2009春夏系列上首次展出了她的成衣系列,并得到了BFC公司和New Gen Scheme的支持。

  20. Mary Grant Seacole: the first nurse practitioner.

    Science.gov (United States)

    Messmer, P R; Parchment, Y

    1998-01-01

    Mary Grant Seacole was born in 1805, in Kingston, Jamaica, to a Jamaican doctress (medicine woman) and a Scottish naval officer. Later Seacole became a doctress, nursing British soldiers during epidemics of cholera, dysentery, and yellow fever in Jamaica, Cuba, and Panama. After refusals by both the British government and Florence Nightingale to be allowed to practice in Scutari, she financed her own way to the scene of the Crimean War and then established the British Hotel to serve both the comfort and medical needs of the wounded soldiers. At night, Seacole worked side by side with Nightingale at Scutari as a volunteer nurse. Seacole's fame grew proportionately after she was seen helping wounded soldiers on the battlefields even while the battles were still raging. Seacole died on May 14, 1881, in London. One hundred years later, many members of the London black community, a few members of the Nurses Association of Jamaica and the Friends of Mary Seacole marched to her grave, honoring her as one of the greatest women of all times. Mary Grant Seacole rose above the barriers of racial prejudice and demonstrated the determinism, compassion, and caring that have became the hallmark of nurse practitioners.

  1. Mountain medicin

    DEFF Research Database (Denmark)

    Bay, Bjørn; Hjuler, Kasper Fjellhaugen

    2016-01-01

    Travelling to high altitudes is an increasingly popular form of recreational holiday. Individual medical advice may be essential for certain groups of individuals such as patients with chronic disorders, pregnant women or children. This is the second part in a series of two articles on mountain...

  2. Changbai Mountains

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    The Changbai Mountains are located within the boundaries of Antu County, Fusong County and Changbai County of Jilin City of Jilin Province. They cover a total area of more than 200,000 hectares and is one of the largest nature preserves in China. There are abundant species of living things, such as Dongbei Tiger, sika, sable and

  3. Farewell Jean-Marie Good Luck Eva Welcome back Franz

    CERN Document Server

    2001-01-01

    At the farewell reception offered by the Director-General, Professor Luciano Maiani, on the occasion of Jean-Marie Dufour's retirement from CERN, three generations of CERN Legal Counsel met. From right to left: Jean-Marie Dufour, who retires on 30 November 2001, after 35 years of service. Eva-Maria Gröniger-Voss, who takes over from Jean-Marie Dufour on 1st December 2001. Ambassador Franz Schmid, CERN Legal Counsel from 1971 to 1974.

  4. Marie and Pierre Curie. Life in extremes; Marie and Pierre Curie. Leben in Extremen

    Energy Technology Data Exchange (ETDEWEB)

    Roethlein, Brigitte

    2008-07-01

    In Paris in 1894, two young physicists fall in love: Marie Sklodowska and Pierre Curie. They get married and make great contributions to science, research radioactivity and discover new chemical elements. The marriage of Marie and Pierre Curie is quite modern: They work together as equals, share their thoughts and pursue their plans together as partners. They share an absolute interest in science, a love of nature, and a sceptic attitude towards the sophisticated society of the Belle Epoque. They are together 24 hours a day with hardly ever any disagreement. Whenever one of them is ill - which is quite often because of the high level of radioactivity in their laboratory -, the other will nurse him or her. After only twelve years of mutual love, Pierre Curie dies. Marie raises their two daughters on her own and continues her research. In 1911, she will be the first scientist that ever gets a second Nobel Prize. (orig.) [German] Im Paris des Jahres 1894 verlieben sich zwei junge Physiker: Marie Sklodowska und Pierre Curie. Sie heiraten und leisten gemeinsam Grosses fuer die Wissenschaft, erforschen die Radioaktivitaet und entdecken neue chemische Elemente. Zusammen erhalten sie den Nobelpreis. Marie und Pierre Curie fuehren eine Ehe, die ihrer Zeit weit voraus ist: Sie arbeiten gleichberechtigt miteinander, teilen ihre Gedanken und verfolgen ihre Plaene gemeinsam. Beiden eigen ist die absolute wissenschaftliche Neugier, die Liebe zur Natur und die Skepsis gegenueber der mondaenen Gesellschaft der Belle Epoque. Fast jeden Tag sind sie rund um die Uhr zusammen, dabei gibt es selten Spannungen. Wenn einer von beiden gesundheitliche Probleme hat - und das haben sie wegen der radioaktiven Belastung im Labor oft - ist der andere fuer ihn da und pflegt ihn. Nach nur zwoelf gemeinsamen Jahren der Liebe und Arbeit stirbt Pierre Curie. Marie zieht ihre beiden Toechter alleine gross und fuehrt die Forschungen weiter. 1911 erhaelt sie als erster Mensch zum zweiten Mal den

  5. Mari Martin - vahelüli looja ja kandja vahel / Mari Martin ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Martin, Mari, 1983-

    2009-01-01

    Kalamari Promotioni tegevjuht, Tartu Ülikoolis majandust õppiv Mari Martin oma esimestest sammudest moemaailmas, kaubamärkide ReUse RePublic (premeeriti noorte äriideede võistlusel "Ajujaht 2009" 175000 krooniga) ja Tallinn Dolls loomisest, eesti disaineritest, unistustest seoses eesti disainiga

  6. Mari Martin - vahelüli looja ja kandja vahel / Mari Martin ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Martin, Mari, 1983-

    2009-01-01

    Kalamari Promotioni tegevjuht, Tartu Ülikoolis majandust õppiv Mari Martin oma esimestest sammudest moemaailmas, kaubamärkide ReUse RePublic (premeeriti noorte äriideede võistlusel "Ajujaht 2009" 175000 krooniga) ja Tallinn Dolls loomisest, eesti disaineritest, unistustest seoses eesti disainiga

  7. Pediatric Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Jani-Acsadi, Agnes; Ounpuu, Sylvia; Pierz, Kristan; Acsadi, Gyula

    2015-06-01

    Heritable diseases of the peripheral nerves (Charcot-Marie-Tooth disease [CMT]) affect the motor units and sensory nerves, and they are among the most prevalent genetic conditions in the pediatric patient population. The typical clinical presentation includes distal muscle weakness and atrophy, but the severity and progression are largely variable. Improvements in supportive treatment have led to better preservation of patients' motor functions. More than 80 genes have been associated with CMT. These genetic discoveries, along with the developments of cellular and transgenic disease models, have allowed clinicians to better understand the disease mechanisms, which should lead to more specific treatments. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Gifts from Mary Ainsworth and John Bowlby.

    Science.gov (United States)

    Crittenden, Patricia M

    2017-07-01

    Attachment theory has developed over many decades - and continues to develop. Its roots lie in several seminal publications of John Bowlby (the basis of attachment theory) and Mary D. S. Ainsworth (the notion of individual differences in attachment). This paper identifies the prescient contributions of these early publications and two processes (a long-term dialogue and reflection on discrepancy) that underlay emergent theory. Because I was a student of Ainsworth when both attachment theory and individual differences in attachment organization were becoming better known, I offer some of my recollections of that period, suggesting how that period may have affected current work in attachment.

  9. Marie Curie's contribution to Medical Physics.

    Science.gov (United States)

    Jean-Claude, Rosenwald; Nüsslin, Fridtjof

    2013-09-01

    On occasion of its 50th anniversary, the International Organization for Medical Physics (IOMP) from now on is going to celebrate annually an International Day of Medical Physics for which the 7th November, the birthday of Marie Sklodowska Curie, a most exceptional character in science at all and a pioneer of medical physics, has been chosen. This article briefly outlines her outstanding personality, sketches her fundamental discovery of radioactivity and emphasizes the impact of her various achievements on the development of medical physics at large.

  10. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  11. Marie and Pierre Curie and radium: history, mystery, and discovery.

    Science.gov (United States)

    Mould, R F

    1999-09-01

    Commencing with Marie Curie's early life in Poland and the discovery of radium in the rue l'Homond "shed" in Paris in 1898, this paper includes some little known facts. It ends with some unusual uses of and claims for radium, and finally, because Medical Physics is an American journal, details are included of Marie Curie's two visits to the USA.

  12. Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2015-01-01

    Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

  13. Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2015-01-01

    Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

  14. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  15. 33 CFR 117.653 - St. Mary's Falls Canal.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Mary's Falls Canal. 117.653 Section 117.653 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Michigan § 117.653 St. Mary's Falls Canal. The draw...

  16. Evaluating Marie Byrd Land stability using an improved basal topography

    Science.gov (United States)

    Holschuh, N.; Pollard, D.; Alley, R. B.; Anandakrishnan, S.

    2014-12-01

    Prior understanding of the ice-sheet setting in Marie Byrd Land (MBL) was derived primarily from geologic and geochemical studies of the current nunataks, with very few geophysical surveys imaging the ice covered regions. The geologic context suggested that the ice rests on a broad regional high, in contrast to the deep basins and trenches that characterize the majority of West Antarctica. This assumed topography would favor long-term stability for the West Antarctic Ice Sheet (WAIS) in MBL. Airborne geophysical data collected in 2009 reveal a much deeper bed than previously estimated, including a significant trough underlying DeVicq Glacier and evidence for extensive glacial erosion. Using these data, we produce a new map of subglacial topography, with which we model the sensitivity of WAIS to a warming ocean using the ice-sheet model of Pollard and DeConto (2012b). We compare the results to estimates of ice loss during WAIS collapse using the previously defined subglacial topography, to determine the impact of the newly discovered subglacial features. Our results indicate that the topographic changes are not sufficient to destabilize the northern margin of MBL currently feeding the Getz Ice Shelf; the majority of ice loss occurs from flow toward the Siple Coast. However, despite only slight dynamic differences, using the new bed as a boundary condition results in an additional 8 cm of sea-level rise during major glacial retreat, an increase of just over 2%. Precise estimation of past and future ice retreat, as well as a complete understanding of the geologic history of the region, will require a higher resolution picture of the bed topography around the Executive Committee mountains.

  17. Rocky Mountain Spotted Fever

    Science.gov (United States)

    ... facebook share with twitter share with linkedin Rocky Mountain Spotted Fever Rocky Mountain spotted fever is a ... New Mexico. Why Is the Study of Rocky Mountain Spotted Fever a Priority for NIAID? Tickborne diseases ...

  18. Roadmap to MaRIE March 2015

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-30

    Los Alamos National Laboratory’s proposed MaRIE facility is slated to introduce the world’s highest energy hard x-ray free electron laser (XFEL). As the light source for the Matter-Radiation Interactions in Extremes experimental facility (MaRIE), the 42-keV XFEL, with bursts of x-ray pulses at gigahertz repetition for studying fast dynamical processes, will help accelerate discovery and design of the advanced materials needed to meet 21st-century national security and energy security challenges. Yet the science of free-electron lasers has a long and distinguished history at Los Alamos National Laboratory (LANL), where for nearly four decades Los Alamos scientists have been performing research, design, development, and collaboration work in FEL science. The work at Los Alamos has evolved from low-gain amplifier and oscillator FEL development to highbrightness photoinjector development, and later, self-amplified spontaneous emission (SASE) and high-gain amplifier FEL development.

  19. Moved by Mary: The power of pilgrimage in the modern world

    NARCIS (Netherlands)

    Hermkens, A.K.; Jansen, W.H.M.; Notermans, C.D.

    2009-01-01

    The Virgin Mary continues to attract devotees to her images and shrines. In Moved by Mary, anthropologists, geographers and historians explore how people and groups around the world identify and join with Mary in their struggle against social injustice, and how others mobilize Mary to impose ideas a

  20. Diagnosis of Charcot-Marie-Tooth Disease

    Directory of Open Access Journals (Sweden)

    Isabel Banchs

    2009-01-01

    Full Text Available Charcot-Marie-Tooth (CMT disease or hereditary motor and sensory neuropathy (HMSN is a genetically heterogeneous group of conditions that affect the peripheral nervous system. The disease is characterized by degeneration or abnormal development of peripheral nerves and exhibits a range of patterns of genetic transmission. In the majority of cases, CMT first appears in infancy, and its manifestations include clumsiness of gait, predominantly distal muscular atrophy of the limbs, and deformity of the feet in the form of foot drop. It can be classified according to the pattern of transmission (autosomal dominant, autosomal recessive, or X linked, according to electrophysiological findings (demyelinating or axonal, or according to the causative mutant gene. The classification of CMT is complex and undergoes constant revision as new genes and mutations are discovered. In this paper, we review the most efficient diagnostic algorithms for the molecular diagnosis of CMT, which are based on clinical and electrophysiological data.

  1. Mary Wigman: the coreography of Carmina Burana

    Directory of Open Access Journals (Sweden)

    Elena Randi

    2012-11-01

    Full Text Available This essay analyses the choreography of Mary Wigman’s Carmina Burana (1955, music by Orff, whose substantial outline Randi can reconstruct primarily through the drawings, partially unpublished, Wigman made to write down the different passages of her dance score. Randi thinks that the characters must not be seen as realistic and that they are the projections of the Vagabond, whose quest is supposed to be the theme underlining the story. The theme of destiny – a destiny on which man has very little or no control – is dominant. The end of the choreography seems to clarify that the self’s quest consists in piétiner sur place: our actions are inevitably sucked under by a whirlpool (represented by the wheel of Fortune choreographically rendered by the figure of the circle and they are unable to bring any significant change. 

  2. Update on Charcot-Marie-Tooth Disease

    Science.gov (United States)

    Patzkó, Ágnes; Shy, Michael E.

    2011-01-01

    Charcot-Marie-Tooth disease (CMT) disease encompasses a genetically heterogeneous group of inherited neuropathies, also known as hereditary motor and sensory neuropathies. CMT results from mutations in more than 40 genes expressed in Schwann cells and neurons causing overlapping phenotypes. The classic CMT phenotype reflects length-dependent axonal degeneration characterized by distal sensory loss and weakness, deep tendon reflex abnormalities, and skeletal deformities. Recent articles have provided insight into the molecular pathogenesis of CMT, which, for the first time, suggest potential therapeutic targets. Although there are currently no effective medications for CMT, multiple clinical trials are ongoing or being planned. This review will focus on the underlying pathomechanisms and diagnostic approaches of CMT and discuss the emerging therapeutic strategies. PMID:21080241

  3. The life and legacy of Marie Curie.

    Science.gov (United States)

    Rockwell, Sara

    2003-01-01

    Marie Curie was a remarkable woman whose discoveries broke new ground in physics and chemistry and also opened the door for advances in engineering, biology, and medicine. She broke new ground for women in science: she was, for example, the first woman to receive a doctor of science degree in France, the first woman to win Nobel Prize, the first woman to lecture at the Sorbonne, the first person to win two Nobel Prizes, and the first Nobel Laureate whose child also won a Nobel Prize. Her life offers insights into the changing role of women in science and academia over the past century. It also offers examples of many ways in which scientists can, and should, work to improve the educational programs and career opportunities available to those who follow in their footsteps.

  4. A bust of Marie Sklodowska Curie at CERN

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The Polish Deputy Minister of Energy and Nuclear Power, J. Felicki, presented the Directors General with a bust of Mme Marie Sklodowska Curie on behalf of physicists of Poland (CERN Courier 19 (1979) 164).

  5. Mari Koger : seina sisse ehitatud akvaariumiga poissmehekodu / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    80-ruutmeetrine poissmehekorter Viimsi uues elamus. Elutoa ja vannitoa vahelises seinas paikneb kahelt poolt vaadeldav akvaarium. Magamistoa üks seintest on ehitatud vanadest tellistest. Sisearhitekt Mari Koger, tema kommentaarid. Ill.: plaan, 9 värv. vaadet

  6. Ämari baas sobib USA-le ja brittidele

    Index Scriptorium Estoniae

    2013-01-01

    Eelmisel nädalal Eestit külastanud USA ja Ühendkuningriigi sõjalised esindajad NATO juures kindralleitnandid David R. Hogg ja Christopher Harper kinnitasid, et on valmis oma lennukeid Ämari baasist opereerima

  7. Mary Carpenter: 19th Century English Correctional Education Hero.

    Science.gov (United States)

    Gehring, Thom; Bowers, Fredalene B.

    2003-01-01

    Describes Mary Carpenter's (1807-1877) work in prison reform and correctional education. Provides biographical information and selections from her writings. (Contains 11 references and a chronology of her work.) (JOW)

  8. Measuring Ankle Instability in Pediatric Charcot-Marie-Tooth Disease.

    Science.gov (United States)

    Mandarakas, Melissa; Hiller, Claire E; Rose, Kristy J; Burns, Joshua

    2013-11-01

    Children with Charcot-Marie-Tooth disease frequently suffer ankle sprain and experience chronic ankle instability; however, no pediatric self-reported measures of chronic ankle instability exist. The aim was to modify and validate the most reliable measure of chronic ankle instability in adults: the Cumberland Ankle Instability Tool. The Cumberland Ankle Instability Tool-Youth was tested for reliability, construct validity, and sensitivity to discriminate between 104 children aged 8 to 16 years: 31 children with Charcot-Marie-Tooth disease, 31 unaffected children with a history of ankle sprains, and 42 controls. Children with Charcot-Marie-Tooth disease had lower scores compared to unaffected children with a history of sprains (χ(2) = 15.10; P Charcot-Marie-Tooth disease.

  9. Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine

    Science.gov (United States)

    ... Issues Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine Past Issues / Winter 2007 Table of Contents For ... Javascript on. Among those attending the NIH MedlinePlus magazine launch on Capitol Hill were (l-r) NIH ...

  10. Deployment of Autonomous GPS Stations in Marie Byrd Land, Antartica

    Science.gov (United States)

    Donnellan, A.; Luyendyk, B.; Smith, M.; Dace, G.

    1999-01-01

    During the 1998-1999 Antarctic field season, we installed three autonomous GPS stations in Marie Byrd Land, West Antarctica to measure glacio-isostatic rebound and rates of spreading across the West Antartic Rift System.

  11. Anneli Remme soovitab : Kuninganna Mary elu ja surm / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2002-01-01

    Kontserdisarja "Hingemuusika" teist kontserti raamivad Henry Purcelli teosed, millest esimene on loodud kuninganna Mary sünnipäevaks, viimane matusetseremooniaks. Barokkansambli Corelli Consort esituses 26., 27., ja 28. apr. Viljandi, Tartu ja Tallinna kirikutes

  12. Marie Curie: In the Laboratory and on the Battlefield

    Science.gov (United States)

    Badash, Lawrence

    2003-07-01

    This year is the centennial of the Nobel Prize in Physics shared by Henri Becquerel and the Curies for their pioneering work on radioactivity. But Marie Curie's contribution to the medical use of x rays is not widely known.

  13. Raamatukogu esisele kerkib kevadel Marie Underi kuju / Andres Eilart

    Index Scriptorium Estoniae

    Eilart, Andres

    2009-01-01

    Skulptor Mati Karminil ja arhitekt Tiit Trummalil valmib valgest marmorist mälestusmärk Marie Underile. Kuju püstitatakse 2010. a. kevadel Eesti Rahvusraamatukogu ette. Alale on kavandatud ka veekaskaadid

  14. Anneli Remme soovitab : Kuninganna Mary elu ja surm / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2002-01-01

    Kontserdisarja "Hingemuusika" teist kontserti raamivad Henry Purcelli teosed, millest esimene on loodud kuninganna Mary sünnipäevaks, viimane matusetseremooniaks. Barokkansambli Corelli Consort esituses 26., 27., ja 28. apr. Viljandi, Tartu ja Tallinna kirikutes

  15. Marie Curie's Doctoral Thesis: Prelude to a Nobel Prize.

    Science.gov (United States)

    Wolke, Robert L.

    1988-01-01

    Traces the life and research techniques of Marie Curie's doctoral dissertation leading to the discovery and purification of radium from ore. Reexamines the discoveries of other scientists that helped lead to this separation. (ML)

  16. Anne-Marie Sargueil: ilu on kasulik / intervjueerinud Emilie Toomela

    Index Scriptorium Estoniae

    Sargueil, Anne-Marie

    2015-01-01

    Prantsuse Disainiinstituudi juht Anne-Marie Sargueil rääkis prantsuse ja skandinaavia disainist, prantslaste disainieelistustest, uutest suundadest disaini valdkonnas, Eesti Tarbekunsti- ja Disainimuuseumis avatud näitusest "20 prantsuse disainiikooni"

  17. Ämari baas sobib USA-le ja brittidele

    Index Scriptorium Estoniae

    2013-01-01

    Eelmisel nädalal Eestit külastanud USA ja Ühendkuningriigi sõjalised esindajad NATO juures kindralleitnandid David R. Hogg ja Christopher Harper kinnitasid, et on valmis oma lennukeid Ämari baasist opereerima

  18. Anne-Marie Sargueil: ilu on kasulik / intervjueerinud Emilie Toomela

    Index Scriptorium Estoniae

    Sargueil, Anne-Marie

    2015-01-01

    Prantsuse Disainiinstituudi juht Anne-Marie Sargueil rääkis prantsuse ja skandinaavia disainist, prantslaste disainieelistustest, uutest suundadest disaini valdkonnas, Eesti Tarbekunsti- ja Disainimuuseumis avatud näitusest "20 prantsuse disainiikooni"

  19. A jolly good call for Marie Curie Fellows

    CERN Multimedia

    2009-01-01

    A new funding opportunity to train young researchers has just been announced by the European Commission. One of the calls within FP7 Marie Curie Actions requests proposals for Initial Training Network (ITN) projects, with a deadline of 22 December 2009. Project proposals are strongly encouraged at CERN and authors can receive support and guidance from the Marie Curie Steering Group. Winnie Wong: "I wouldn’t have considered a PhD if I hadn’t been a Marie Curie fellow" Dan Savu: "It’s the best of both worlds: training plus working in an international organisation" ITN projects have one key aim: training. Academic and industrial partners work together to form a network to recruit and train Marie Curie Fellows. Fellows are young researchers (typically PhD-level) from any country who combine project-based research with tailor-made training programmes, ...

  20. Referrals to the Marie Curie nursing service in North Yorkshire.

    Science.gov (United States)

    Hanratty, B; Feather, J; Ward, C

    2000-01-01

    District and Marie Curie nurses participated in a small-scale study to describe referrals to a Marie Curie service in one English health district over a 3-month period. The number of new patients referred was small; they were geographically clustered and had widely differing life expectancies. Anecdotal reports of difficulties with the 'Nurselink' referral system were not confirmed, and in situations where the system was in operation, Marie Curie nurses were more likely to speak directly to the referring nurse. The most frequently cited reason for referral was general nursing needs; however, Marie Curie nurses felt that they were most often involved to provide family support. These findings suggest that there may not be a shared understanding of the Marie Curie nurse's role, and that equity in community palliative nursing care merits examination. Defining and publicizing the role of the Marie Curie nurse, providing guidance for referrals and prioritizing communication between professionals are proposed not only to enhance the service locally but to ensure that the service is available to all. This article illustrates the value of research to identify ways to improve service delivery.

  1. [Pathology of Charcot-Marie-Tooth Disease].

    Science.gov (United States)

    Oka, Nobuyuki

    2016-01-01

    Although genetic testing is available, nerve biopsy is useful in selected patients for the diagnosis of Charcot-Marie-Tooth disease (CMT). These are sporadic cases of hereditary neuropathy, or familial cases in which genetic testing is negative. CMT is caused by mutations of various genes. The pathological features of CMT have mostly been investigated using nerve biopsy, which may shed light on the presumed functions of mutated gene products. PMP22 duplication in CMT1A induces numerous large onion bulb lesions (OB). Compared to chronic inflammatory demyelinating polyradiculoneuropathy, the differential features of CMT1A are patchy distribution of OB and non-inflammatory lesions. CMT1B also manifests as OB, but presents abnormal compaction of myelin sheaths caused by uncompacted myelin or excessive myelin folding. CMT2 includes axonal neuropathies and many causative genes have been found. CMT2A (MFN2 mutation) shows abnormal mitochondria with a spherical morphology instead of tubular in the longitudinal direction. CMT4 consists of autosomal recessive forms with demyelinating pathology. Most subtypes have mutations of genes relating to myelin maintenance, and pathologically, they show abnormal folding of the myelin structure.

  2. Acute mountain sickness

    Science.gov (United States)

    High altitude cerebral edema; Altitude anoxia; Altitude sickness; Mountain sickness; High altitude pulmonary edema ... Acute mountain sickness is caused by reduced air pressure and lower oxygen levels at high altitudes. The faster you ...

  3. Põhja-Eesti Regionaalhaigla X-korpus = North-Estonian Regional Hospital X-wing / Mari Kurismaa ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2011-01-01

    Tallinnas Sütiste tee 19 asuva haigla juurdeehitise sisekujundusest. Sisearhitekt Mari Kurismaa (Stuudio Kurismaa OÜ). Arhitektid Indrek Suigusaar, Vivian Oruvee (AB Pluss OÜ). Infograafika autor Mari Kaljuste

  4. Põhja-Eesti Regionaalhaigla X-korpus = North-Estonian Regional Hospital X-wing / Mari Kurismaa ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2011-01-01

    Tallinnas Sütiste tee 19 asuva haigla juurdeehitise sisekujundusest. Sisearhitekt Mari Kurismaa (Stuudio Kurismaa OÜ). Arhitektid Indrek Suigusaar, Vivian Oruvee (AB Pluss OÜ). Infograafika autor Mari Kaljuste

  5. Recent advances in Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Baets, Jonathan; De Jonghe, Peter; Timmerman, Vincent

    2014-10-01

    This article focuses on recent advances in Charcot-Marie-Tooth disease, in particular additions to the genetic spectrum, novel paradigms in molecular techniques and an update on therapeutic strategies. Several new Charcot-Marie-Tooth disease-causing genes have been recently identified, further enlarging the genetic diversity and phenotypic variability, including: SBF1, DHTKD1, TFG, MARS, HARS, HINT1, TRIM1, AIFM1, PDK3 and GNB4. The increasing availability and affordability of next-generation sequencing technologies has ramped up gene discovery and drastically changed genetic screening strategies. All large-scale trials studying the effect of ascorbic acid in Charcot-Marie-Tooth 1A have now been completed and were negative. Efforts have been made to design more robust outcome-measures for clinical trials. Promising results with lonaprisan, curcumin and histone deacetylase 6 inhibitors have been obtained in animal models. Charcot-Marie-Tooth is the most common form of inherited peripheral neuropathy and represents the most prevalent hereditary neuromuscular disorder. The genetic spectrum spans more than 70 genes. Gene discovery has been revolutionized recently by new high-throughput molecular technologies. In addition, the phenotypic diversity has grown tremendously. This is a major challenge for geneticists and neurologists. No effective therapy is available for Charcot-Marie-Tooth. Several large trials with ascorbic acid were negative but research into novel compounds continues.

  6. Soils of Marie Byrd Land, West Antarctica

    Science.gov (United States)

    Lupachev, A. V.; Abakumov, E. V.

    2013-10-01

    Soils of Marie Byrd Land-one of the remotest and difficultly accessible regions of Antarctica-were investigated in the area of the mothballed Russkaya station located to the south of 74° S. Despite the extremely severe wind regime (the average wind velocity is 13 m/s, and the maximum wind velocity is up to 60 m/s), the projective cover of vegetation in the area of the station averages 25-40% and reaches 60-80% in some places. The phenomena of physical weathering of the bedrock-exfoliation, stone pavements, residual rocks exposed by wind (hoodoos), and others-are clearly manifested. In most of the described soils, normal organic and organomineral horizons are absent. The soil profiles represent the mixture of the residues of mosses and lichens and the gravelly eluvium. The fine earth material is blown out of the surface horizons by strong winds; its residual accumulation takes place in the middle and lower parts of the profiles. The classification position of these soils is open to argument; they are close to Petrozems and Lithozems. Most of the profiles are underlain by the massive or slightly disintegrated bedrock with dry permafrost at a depth of 20 to 50 cm. Soils with dry permafrost comprise about 75% of the surveyed area. In separate loci in the depressions of the local mesorelief and on gentle slopes, the soils with clearly expressed cryoturbation features are developed; their profiles are underlain by the ice-rich permafrost and compose about 15% of the surveyed area. Anthropogenically disturbed soils and soils polluted with petroleum hydrocarbons, heavy metals, and other pollutants occupy about 10% of the surveyed area.

  7. [Marie Heiberg. Üks naine kurbade silmadega] / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    2010-01-01

    Arvustus: Heiberg, Marie. Üks naine kurbade silmadega : Eesti luuletaja Marie Heibergi õnne ja valu, rõõmu ja mure lugu kirjades / [koostajad Iivi Lepik, Kirsten Simmo]. Tallinn : Eesti Teatri- ja Muusikamuuseum : SE & JS, 2010

  8. 78 FR 14653 - Amendment of Class E Airspace; Sault Ste Marie, ON

    Science.gov (United States)

    2013-03-07

    ... control zone over Sault Ste Marie Airport. The FAA is taking this action to enhance the safety and... Airport, Sault Ste Marie, ON, to coincide with that portion of the control zone in Canadian airspace....

  9. Water resources and potential effects of ground-water development in Maggie, Marys, and Susie Creek basins, Elko and Eureka counties, Nevada

    Science.gov (United States)

    Plume, R.W.

    1995-01-01

    The basins of Maggie, Marys, and Susie Creeks in northeastern Nevada are along the Carline trend, an area of large, low-grade gold deposits. Pumping of ground water, mostly for pit dewatering at one of the mines, will reach maximum rates of about 70,000 acre-ft/yr (acre-feet per year) around the year 2000. This pumping is expected to affect ground-water levels, streamflow, and possibly the flow of Carlin spring, which is the water supply for the town of Carlin, Nev. Ground water in the upper Maggie Creek Basin moves from recharge areas in mountain ranges toward the basin axis and discharges as evapotranspiration and as inflow to the stream channel. Ground water in the lower Maggie, Marys, and Susie Creek Basins moves southward from recharge areas in mountain ranges and along the channel of lower Maggie Creek to the discharge area along the Humboldt River. Ground-water underflow between basins is through permeable bedrock of Schroeder Mountain from the upper Maggie Creek Basin to the lower Maggie Creek Basin and through permeable volcanic rocks from lower Maggie Creek to Carlin spring in the Marys Creek Basin. The only source of water to the combined area of the three basins is an estimated 420,000 acre-ft/yr of precipitation. Water leaves as runoff (38,000 acre-ft/yr) and evapotranspiration of soil moisture and ground water (380,000 acre-ft/yr). A small part of annual precipitation (about 25,000 acre-ft/yr) infiltrates the soil zone and becomes ground-water recharge. This ground water eventually is discharged as evapotranspiration (11,000 acre-ft/yr) and as inflow to the Humboldt River channel and nearby springflow (7,000 acre-ft/yr). Total discharge is estimated to be 18,000 acre-ft/yr.

  10. Jean-Marie Dufour receives the Legion of Honour

    CERN Multimedia

    2001-01-01

    French Ambassador Philippe Petit (left) presents the cross of Knight of the Légion d'Honneur to Jean-Marie Dufour. On Friday 22 June, Jean-Marie Dufour, Head of CERN's Legal Service, was made Knight of the Legion of Honour by Ambassador Philippe Petit, at a ceremony held at the Permanent Mission of France in Geneva. Ambassador Petit is Permanent Representative of France at the United Nations and French delegate at CERN. He was awarded the decoration in recognition of his services. He has played an active part in all the great stages of CERN's development, in fact, ranging from its scientific programmes, to its establishment in its Host States, Switzerland and France, and its opening up to the wider world. The ceremony took place in the presence of Professor Luciano Maiani. The award is an honour to CERN, and the Organization takes this opportunity to convey its friendliest congratulations to Jean-Marie Dufour, a committed European.

  11. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology

    CERN Document Server

    Patrice Loiez

    2002-01-01

    Photo 0210004_1: Prof. Ugo Amaldi, University of Milano Bicocca and Tera Foundation, Italy. Addressing the Marie Curie Workshop held at CERN 3-4 October 2002. Title of this talk:"Research Developments on Medical Physics". Photo 0210004_2: Marie Curie Fellows at CERN. Participating in Marie Curie Workshop held at CERN 3-4 October 2002.

  12. 33 CFR 207.440 - St. Marys Falls Canal and Locks, Mich.; use, administration, and navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false St. Marys Falls Canal and Locks.... Marys Falls Canal and Locks, Mich.; use, administration, and navigation. (a) The use, administration... by radiotelephone to the Corps of Engineers Chief Lockmaster at St. Marys Falls Canal dispatch...

  13. [Charcot-Marie-Tooth disease and bilateral vitritis].

    Science.gov (United States)

    Anaya-Pava, E J; Cárdenas-Hernández, R I

    2015-04-01

    We describe a patient diagnosed with Charcot-Marie-Tooth disease, with a 4 months history of bilateral decreased visual acuity and floaters. On examination, he had severe bilateral vitreous opacity and sectoral diffuse vascular sheathing. It could not be linked to some underlying aetiology and did not respond to oral steroids. Publications relating to ocular findings in patients with Charcot-Marie-Tooth disease exclude bilateral vitritis. In this case we were unable to test the association with another disease as the cause of vitritis. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  14. Esther Schor, ed. The Cambridge Companion to Mary Shelley

    Directory of Open Access Journals (Sweden)

    Anne BERTON

    2006-06-01

    Full Text Available “Today, whether she is found between staid cloth covers, in paperback, on the screen or in cyberspace, Mary Shelley is everywhere,” writes Esther Schor in her Introduction to this collection of essays (2. Interest in “the Author of Frankenstein” and of other works has grown steadily over the last twenty years, thanks notably to the publication of her Journals (The Journals of Mary Shelley, 1814-1844, ed. Paula R. Feldman and Diana Scott-Kilvert, 2 vols, Oxford: Clarendon, 1987, of her Lette...

  15. ANESTHESIA FOR CHARCOT-MARIE-TOOTH DISEASE: CASE REPORT.

    Science.gov (United States)

    Alzaben, Khalid R; Samarah, Omar Q; Obeidat, Salameh S; Halhouli, Oday; Al Kharabsheh, Murad

    2016-06-01

    Charcot-Marie-Tooth disease comprises a group of disorders characterized by progressive muscle weakness and wasting. Reviewing the anaesthetic literature produced conflicting reports about the best anaesthetic options for patients with CMTD; as they are at increased risk of prolonged response to muscle relaxants, malignant hyperthermia and risks of regional anaesthesia. We present a case of the successful use of total intravenous anaesthesia with dexmedetomidine and propofol combined with caudal block using bupivacaine mixed with dexmedetomidine without any complications, for a 17 year old male patient with Charcot Marie-Tooth disease who underwent a lower limb orthopedic surgery.

  16. Mary Boole and curve stitching: a look into heaven.

    Science.gov (United States)

    Innes, Shelley

    2004-03-01

    Mary Everest Boole had a lifelong interest in the unconscious mind, the psychology of learning, and how these relate to the teaching of mathematics and science. She recommended many practical exercises and teaching aids, one of which was the technique of curve stitching, which she had invented while still a child herself.

  17. Paying tribute to florence nightingale and Mary Seacole.

    Science.gov (United States)

    Grainger, Angela

    2012-05-30

    Lynn McDonald (letters May 16) says the grounds of St Thomas' Hospital in London are the wrong place for the proposed memorial statue to Mary Seacole, pointing out that the hospital is more associated with Florence Nightingale and her work.

  18. Romanticism or Reality? An Exploration of Frances Mary Hendry's "Chandra."

    Science.gov (United States)

    Johnson, Jilaine

    This paper singles out a novel written for children about India, "Chandra" (1995) by Frances Mary Hendry, as a powerful and useful novel to present to today's 11 to 14 year old students. The paper contends that the novel allows students to explore and consider different value systems, challenges them to become aware of prejudice and the…

  19. Molecular Diagnosis of Charcot-Marie Tooth Disease

    Directory of Open Access Journals (Sweden)

    J. Gordon Millichap

    2002-02-01

    Full Text Available The frequency of mutations in certain genes in 153 unrelated patients with Charcot-Marie-Tooth disease (CMT was determined by DNA sequencing before clinical testing at the Departments of Molecular and Human Genetics and Pediatrics, Baylor College of Medicine, Houston, TX, and other centers.

  20. Charcot-Marie-Tooth disease type 1A

    DEFF Research Database (Denmark)

    Hertz, Jens Michael; Børglum, A D; Brandt, C A

    1994-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) is an autosomal dominant peripheral neuropathy associated with a DNA duplication on chromosome 17p11.2-p12 in the majority of cases. Most of the sporadic cases are due to a de novo duplication. We have screened for this duplication in 11 Danish patients...

  1. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  2. Naine : masin või loom? / Maris Palgi

    Index Scriptorium Estoniae

    Palgi, Maris

    2007-01-01

    Eero Taltsi, Margus Kiisi, Maia Mölleri, Kaie Luige, Eva Orava ja Maris Palgi projektist "Maine-loom, naine-masin", mida tutvustati 2006. a. Moostes üritusel "Postsovkhoz 6", 2007. a. jaanuaris-veebruaris Tartu Kunstimajas ja Tartu Tampere Majas. Näitused avati E. Taltsi ja M. Kiisi loeng-performance'itega

  3. Reklaamid nagu kino / Jean Marie Bouriscot ; interv.Valner Valme

    Index Scriptorium Estoniae

    Bouriscot, Jean Marie

    2001-01-01

    Sakala keskuses toimus reedel 6. korda reklaamiõgijate öö, kus näidati reklaamiklippe Jean Marie Bouriscotþ kogust. Kogu omanik polnud küll seekord ise kohal, kuid vastas siiski ajakirjaniku küsimustele oma huviala kohta

  4. From security to attachment : Mary Ainsworth's contribution to attachment theory

    NARCIS (Netherlands)

    Rosmalen, Lenette (Lenny) van

    2015-01-01

    Even though John Bowlby (1907-1990) is generally regarded as the founder of attachment theory, Mary Ainsworth’s (1913-1999) contribution is considerable and goes beyond the design of the Strange Situation Procedure and the introduction of maternal sensitivity as decisive for a secure attachment

  5. The Antibureaucrat: Mary Graham--Brooklyn Public Library, NY

    Science.gov (United States)

    Library Journal, 2004

    2004-01-01

    It is tough to make the staff of a large, highly centralized urban library system believe they should make their own decisions and even take risks--all to serve their community better. But that is what Mary Graham has achieved as Brooklyn Public Library's director of the Office of Neighborhood Services. A study of Brooklyn Public Library (BPL) in…

  6. Missionary Education in Colonial Africa: The Critique of Mary Kingsley.

    Science.gov (United States)

    Pearce, Robert

    1988-01-01

    Discussing missionary education in colonial Africa, Pearce examines the ideas of Mary Kingsley, one of the major influences on British thinking towards Africa from the late 1890's. Focusing attention on her educational views, Pearce states that she had influence on all areas of British policy in Africa, and especially West Africa. (GEA)

  7. A Day in the Life of Mary Cassatt.

    Science.gov (United States)

    Stoppel, Julie

    2002-01-01

    Offers a way to present art history to classroom students where the art teacher pretends to be an artist. Focuses on a lesson where the teacher pretended to be Mary Cassatt. States that the students used pastels when drawing their artwork, in conjunction with the art history lesson. (CMK)

  8. Mary E. Hall: Dawn of the Professional School Librarian

    Science.gov (United States)

    Alto, Teresa

    2012-01-01

    A century ago, a woman named Mary E. Hall convinced school leaders of the need for the professional school librarian--a librarian who cultivated a love of reading, academic achievement, and independent learning skills. After graduating from New York City's Pratt Institute Library School in 1895, Hall developed her vision for the high school…

  9. Lift as You Climb: A Profile of President Mary Vosevich

    Science.gov (United States)

    Blumenthal, Anita

    2012-01-01

    "My thumb got me into this!" declares the new APPA President Mary Vosevich when asked how she entered the field of educational facilities management. It was 1984, and Vosevich, a Midwest native, was working at Monsanto in St. Louis as a research biologist, having earned her B.S. in horticulture/agriculture from the University of…

  10. Hüljatud Eesti moodi / Maris Leif ; interv. Sven Haljand

    Index Scriptorium Estoniae

    Leif, Maris

    2006-01-01

    Ilmunud ka: Den za Dnjom 27. jaan. lk. 6-7. President Arnold Rüütli tütar Maris Leif vastab küsimustele, mis puudutavad tema suhteid oma vanemate, laste, õe ja endise abikaasa Olav Leifiga ning selgitab, miks tema tütred Maria ja Helena on vanavanemate kasvatada

  11. Para uma espiritualidade leiga: Marià Corbí

    Directory of Open Access Journals (Sweden)

    Marta Granés Bayona

    2015-04-01

    Full Text Available Recensión:CORBI, Marià. Para uma espiritualidade leiga. São Paulo: Paulus, 2010. 294 p. [Hacia una espiritualidad laica, sin creencias, sin religiones, sin dioses. Barcelona: Herder, 2007, 350 p.]  

  12. Response to Mary J. Reichling, "Intersections: Form, Feeling, and Isomorphism"

    Science.gov (United States)

    Sinclair, Anne

    2004-01-01

    In her response to Mary Reichling's article "Intersections: Form, Feeling, and Isomorphism, Anne Sinclair believes that the exploration of form, feeling, and isomorphism in the writings of Susanne Langer accomplishes its goal to examine and elucidate aspects of these concepts. Sinclair finds several of the ideas presented very engaging. Musical…

  13. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  14. Rosie Carpe and the Virgin Mary: Modelling Modern Motherhood

    Directory of Open Access Journals (Sweden)

    Pauline Eaton

    2016-06-01

    Full Text Available Marie NDiaye’s 2001 novel, Rosie Carpe, incorporates, as one of its several instances of parenting failure, the narrative of the decline of a single mother from adequacy to abuse. This narrative, which is the focus of this article, might be said to put flesh on the bones of Julia Kristeva’s deconstruction of the Virgin Mary in her 1980s essay ‘Stabat Mater’. Kristeva saw the Marian model as out of date but she interrogated its enduring power and its continuing influence on our cultural perceptions of maternity. NDiaye’s eponymous Rosie realises she is pregnant but has no idea how this has come about. Rosie is not represented as a woman who has a religious faith but she decides to accept her child as a holy miracle. This article analyses how the ‘mythology’ of the Virgin Mary, and other biblical intertext, is woven into the narrative of Rosie’s experience of motherhood, so as to counterpoint and illuminate Rosie’s bleak and raw inner experience of maternity, an experience which, while confirming that Rosie is not, and never could have been, a modern Virgin Mary nevertheless refreshes the human stories at the root of the Christian narrative.

  15. PARTNER: A Marie Curie Initial Training Network for hadron therapy

    CERN Document Server

    CERN BULLETIN; Nathalie Hospital; Manuela Cirilli

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  16. Reklaamid nagu kino / Jean Marie Bouriscot ; interv.Valner Valme

    Index Scriptorium Estoniae

    Bouriscot, Jean Marie

    2001-01-01

    Sakala keskuses toimus reedel 6. korda reklaamiõgijate öö, kus näidati reklaamiklippe Jean Marie Bouriscotþ kogust. Kogu omanik polnud küll seekord ise kohal, kuid vastas siiski ajakirjaniku küsimustele oma huviala kohta

  17. Naine : masin või loom? / Maris Palgi

    Index Scriptorium Estoniae

    Palgi, Maris

    2007-01-01

    Eero Taltsi, Margus Kiisi, Maia Mölleri, Kaie Luige, Eva Orava ja Maris Palgi projektist "Maine-loom, naine-masin", mida tutvustati 2006. a. Moostes üritusel "Postsovkhoz 6", 2007. a. jaanuaris-veebruaris Tartu Kunstimajas ja Tartu Tampere Majas. Näitused avati E. Taltsi ja M. Kiisi loeng-performance'itega

  18. Mountain Plover [ds109

    Data.gov (United States)

    California Department of Resources — Point locations representing observations of mountain plover (Charadrius montanus) feeding and roosting flocks (and occasional individuals) documented during an...

  19. Marie and Irene Curie. The first female Nobel Prize winners; Marie en IreneCurie. De eerste vrouwelijke Nobelprijswinnaars

    Energy Technology Data Exchange (ETDEWEB)

    Noordenbos, G. [Joke Smit Instituut voor Vrouwenstudies, Universiteit Leiden, Leiden (Netherlands)

    2003-07-01

    Marie Curie was awarded the Nobel Prize in 1903 and in 1911. Also her daughter, Irene Joliot-Curie, received a Nobel Prize for science in 1935. In this book an overview is given of the academic world at that time: limited access to universities for women, the carriers of both women in physics and their pioneering research and discoveries, the refusal of Marie Curie by the French Academy of Sciences, the awarding of the Nobel Prize and the assignment of Irene Joliot-Curie as the first female minister in France, the impact of the two World Wars, their married and private lives and the constant smear campaign of the press against both women. The lives and works of both women are hold against the light of the present position of women in physical sciences. [Dutch] In 1903, precies honderd jaar geleden, ontving Marie Curie als eerste vrouw de Nobelprijs voor de Wetenschap, gevolgd door een tweede Nobelprijs in 1911. Ook haar dochter Irene Joliot-Curie kreeg de Nobelprijs voor de wetenschap in 1935. Marie and Irene Curie schetst een breed beeld van de academische wereld waarin beide vrouwen zich bewogen: de beperkte toegang van vrouwen tot de universiteit, hun carrisres in de natuurkunde en baanbrekende ontdekkingen, de afwijzing van Marie door de Franse Academie des Sciences, de toekenning van de Nobelprijs en de benoeming van Irene als eerste vrouwelijke minister in Frankrijk, de invloed van de twee Wereldoorlogen, hun huwelijks- en priveleven en de niet aflatende hetze van de pers tegen beiden. In de door mannen gedomineerde wereld van de natuurwetenschappen liep de uitzonderingspositie van beide vrouwen als rode draad door hun curieuze levens. Het leven en werk van de Curies wordt geactualiseerd door deze tegen het licht te houden van de huidige positie van vrouwen in de natuurwetenschappen. Het bereiken van de top van de wetenschap door vrouwen blijkt nog steeds uitzonderlijk.

  20. Mountain Pine Beetle

    Science.gov (United States)

    Gene D. Amman; Mark D. McGregor; Robert E. Jr. Dolph

    1989-01-01

    The mountain pine beetle, Dendroctonus ponderosae Hopkins, is a member of a group of beetles known as bark beetles: Except when adults emerge and attack new trees, the mountain pine beetle completes its life cycle under the bark. The beetle attacks and kills lodgepole, ponderosa, sugar, and western white pines. Outbreaks frequently develop in lodgepole pine stands that...

  1. Mountain chickadee (Poecile gambeli)

    Science.gov (United States)

    McCallum, D. Archibald; Grundel, Ralph; Dahlsten, Donald L.; Poole, Alan; Gill, Frank

    1999-01-01

    The Mountain Chickadee (Poecile gambeli), a small, cavity-nesting songbird, is one of the most common birds of montane and coniferous forest from southern Arizona and Baja California north to British Columbia and the Yukon territory. This publication describes the life history of the Mountain Chickadee.

  2. 33 CFR 165.T09-0290 - Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. 165.T09-0290 Section 165.T09-0290... Limited Access Areas Ninth Coast Guard District § 165.T09-0290 Safety Zones; Blasting Operations...

  3. Nanoparticle de-acidification of the Mary Rose

    Directory of Open Access Journals (Sweden)

    Eleanor J. Schofield

    2011-07-01

    Full Text Available The preservation of waterlogged archaeological wooden finds, such as Henry VIII's flagship the Mary Rose1–3, is complicated by the biological, chemical, and mechanical changes induced from prolonged exposure to a marine environment. Of particular concern are sulfur species that form acidic compounds that attack wood4. Here we show that different sulfur compounds do not form acids at the same rate or pathway and propose a preservation strategy of applying SrCO3 nanoparticles. These nanoparticles not only neutralize problematic sulfuric acid, but also reduced sulfur compounds, such as sulfur and pyrite, which pose a long term threat. This is the first treatment that eliminates acidification at the root. Although this strategy was devised for the Mary Rose, it could be employed to preserve any archaeological organic artifact rich in problematic sulfur, from sunken ships5,6 and silk tapestries7 to ancient texts8 and parchments9.

  4. Mary Shelley's Frankenstein: what made the Monster monstrous?

    Science.gov (United States)

    Britton, Ronald

    2015-02-01

    This paper discusses the genesis of the famous story of Frankenstein which arose from a dream experienced by Mary Shelley whilst on a holiday shared with her husband Percy Shelley, Lord Byron, Dr Polidori and her step sister Claire Clairmont. The novel relates how the creature created by Victor Frankenstein horrifies him, is rejected by him and called a monster. The monster's ensuing despair and subsequent murderousness is eloquently described. The whole book is clearly connected to Mary Shelley's experience as an infant whose mother died after giving birth to her and her subsequent loss, as a mother, of her own new born infant. It is suggested that the novel imaginatively describes what it is to have been primarily rejected as an infant and to feel regarded as a monster.

  5. La modernidad electiva en Mariátegui

    Directory of Open Access Journals (Sweden)

    José Sazbón

    2001-01-01

    Full Text Available La originalidad de Mariátegui como político y pensador socialista ha sido estudiada desde diversas perspectivas. En este trabajo, la atención está centrada en su explícita vocación de “modernidad”, entendida como exigencia de integración del marxismo a las aperturas del pensamiento contemporáneo: filosofía, ciencias y artes, pero también renovada sensibilidad para las intuiciones vitales suscitadas por las convulsiones sociales y políticas de las primeras décadas del siglo. Luego de indicar la significación que revistió para Mariátegui el aporte soreliano -y su coordinación con las opciones indicadas-, se concede importancia a los recursos expresivos de la prosa mariateguiana, inusuales y encomiables.

  6. Experimental Physical Sciences Vistas: MaRIE (draft)

    Energy Technology Data Exchange (ETDEWEB)

    Shlachter, Jack [Los Alamos National Laboratory

    2010-09-08

    To achieve breakthrough scientific discoveries in the 21st century, a convergence and integration of world-leading experimental facilities and capabilities with theory, modeling, and simulation is necessary. In this issue of Experimental Physical Sciences Vistas, I am excited to present our plans for Los Alamos National Laboratory's future flagship experimental facility, MaRIE (Matter-Radiation Interactions in Extremes). MaRIE is a facility that will provide transformational understanding of matter in extreme conditions required to reduce or resolve key weapons performance uncertainties, develop the materials needed for advanced energy systems, and transform our ability to create materials by design. Our unique role in materials science starting with the Manhattan Project has positioned us well to develop a contemporary materials strategy pushing the frontiers of controlled functionality - the design and tailoring of a material for the unique demands of a specific application. Controlled functionality requires improvement in understanding of the structure and properties of materials in order to synthesize and process materials with unique characteristics. In the nuclear weapons program today, improving data and models to increase confidence in the stockpile can take years from concept to new knowledge. Our goal with MaRIE is to accelerate this process by enhancing predictive capability - the ability to compute a priori the observables of an experiment or test and pertinent confidence intervals using verified and validated simulation tools. It is a science-based approach that includes the use of advanced experimental tools, theoretical models, and multi-physics codes, simultaneously dealing with multiple aspects of physical operation of a system that are needed to develop an increasingly mature predictive capability. This same approach is needed to accelerate improvements to other systems such as nuclear reactors. MaRIE will be valuable to many national

  7. Tapatumo problema Marie Ndiaye romanuose | Le probleme d’identite dans les romans de Marie Ndiaye

    Directory of Open Access Journals (Sweden)

    Eglė Kačkutė

    2004-01-01

    Full Text Available L’article traite le problème de l’identité féminine dans les deux derniers romans de l’auteur française Marie Ndiaye La Sorcière et Rosie Carpe. La notion d’identité est abordée à travers des théories contemporaines d’identité, résumées par Calvin O. Schrag dans le livre The Self After Postmodernity (Le Soi après la Postmodernité, et celle de Judith Butler. Nous nous concentrons sur trois aspects d’identité : discursif, actif et communautaire. L’auteur de l’article se pose pour but de prouver que la résolution du problème d’identité dans la littérature des femmes a changé dans les dix dernières années. Les écrivains femmes des années 70 et 80 posent le problème d’identité féminine de point de vue du genre, tandis que Ndiaye présente le problème du point de vue universel, c’est-à-dire, communautaire et social. L’identité chez Ndiaye ne peut pas être établie qu’à travers la communauté sociale représentée par la famille. Nous parvenons à la conclusion que les personnages des romans analysés, étant à la recherche perpétuelle de leur identité ne parviennent quand même pas à la créer.

  8. Baltika kvartal = Baltika Quarter / Maris Kerge, Kadri Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2010-01-01

    Rekonstrueeritud Baltika tööstushoonest: Moetänavast ja AS Baltika büroodest. Projekteerija, sisearhitektuur büroode osas: Studio 3 (4 arhitekti), büroo Kolm Pluss Üks (9 arhitekti). Sisearhitektuur Moetänava osas: Pekka Porkanen, Maris Kerge, Ott Kangur, Maire Milder, Lembit-Kaur Stöör, Ülo-Tarmo Stöör, Lauri Eltermaa, Pärtel Eelma. Projekt: 2007-2009, valmis: 2009

  9. Global Supply Chain: An Executive Interview with Mary Shelman

    OpenAIRE

    Jose, H. Douglas

    2009-01-01

    Mary Shelman discusses forces driving higher food prices and some of the changes which are impacting the global food supply chain. Shelman coordinates Harvard Business School’s premier Agribusiness Seminar attended annually by more than 200 CEOs and top managers from global firms. She also organizes and teaches similar programs in Europe, Latin America and Asia. Her research focuses on the forces shaping global agribusiness. Her experience bridges academia, as an author and teacher of dozen...

  10. Baltika kvartal = Baltika Quarter / Maris Kerge, Kadri Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2010-01-01

    Rekonstrueeritud Baltika tööstushoonest: Moetänavast ja AS Baltika büroodest. Projekteerija, sisearhitektuur büroode osas: Studio 3 (4 arhitekti), büroo Kolm Pluss Üks (9 arhitekti). Sisearhitektuur Moetänava osas: Pekka Porkanen, Maris Kerge, Ott Kangur, Maire Milder, Lembit-Kaur Stöör, Ülo-Tarmo Stöör, Lauri Eltermaa, Pärtel Eelma. Projekt: 2007-2009, valmis: 2009

  11. Rahvarõiva uus tulek / Mari Ird ; interv. Irene Roos

    Index Scriptorium Estoniae

    Ird, Mari

    2004-01-01

    Aastaid ajalooliselt õigeid Eesti rahvarõivaid loonud Mari Ird sellest, kuidas tänäpäeval rahvarõivaid valida, kanda ja hoida. Eesti rahvarõivaste huvitavatest tagamaadest, pidamise, käima-, seisu-, meeste, naiste ja laste rõivastest, pruudikroonist, jalanõudest. 14 ill.: Ruhnu naise rõivaste kolm varianti, Mulgi kihelkonna meeste, Karja kihelkonna naiste ja Pöide lesknaise riided

  12. Trans-Colonial Collaboration and Slave Narrative: Mary Prince Revisited

    Directory of Open Access Journals (Sweden)

    Michelle Gadpaille

    2011-10-01

    Full Text Available In 1831 in London, two formidable women met: Mary Prince, an ex-slave from Bermuda, who had crossed the Atlantic to a qualified freedom, and Susanna Strickland, an English writer. The narrative that emerged from this meeting was The History of Mary Prince, which played a role in the fight for slave emancipation in the British Empire. Prince disappeared once the battle was won, while Strickland emigrated to Upper Canada and, as Susanna Moodie, became an often quoted 19th century Canadian writer. Prince dictated, Strickland copied, and the whole was lightly edited by Thomas Pringle, the anti-slavery publisher at whose house the meeting took place. This is the standard account. In contesting this version, the paper aims to reinstate Moodie as co-creator of the collaborative Mary Prince text by considering multiple accounts of the meeting with Prince and to place the work in the context of Moodie’s pre- and post-emigration oeuvre on both sides of the Atlantic.

  13. The Pasteurization of Marie Curie: A (meta)biographical experiment.

    Science.gov (United States)

    Wirtén, Eva Hemmungs

    2015-08-01

    Biographies of scientists occupy a liminal space, highly popular with general readers but questioned in academia. Nonetheless, in recent years, historians of science have not only embraced the genre with more enthusiasm and less guilt, they have also turned to the metabiography in order to renew the study and story of scientists' roles. This essay focuses on Marie Curie, the world's most famous female scientist, in order to unpack some of the theoretical and methodological claims of the science biography, and especially to address the sexing mechanisms at play in the construction of the biographical subject. Pierre Curie (1923), Marie's biography of her husband Pierre, paid tribute to her dead husband and collaborator, but also allowed Curie a legitimate outlet to construct her own persona and legacy. Categories such as personhood, person, and persona are not only central to the biography genre but also are essential to the sense of self and self-fashioning of scientists. Looking at how Marie Curie negotiated these categories in Pierre Curie not only gives new insight into Curie's self-fashioning strategies but may also shed some light on the more general analytical lacunae of the science biography.

  14. Revisiting Mary Daly: Towards a quadripartite theological and philosophical paradigm

    Directory of Open Access Journals (Sweden)

    Hannelie Wood

    2015-03-01

    Full Text Available I was a tenderfoot in feminist discourse when I started my research on patriarchy, feminism, and Mary Daly. In my thesis, one aspect I engaged was Daly’s battle with gender issues in Christian theology. From the beginning I was troubled by Mary Daly’s views on God, men, and women in her discourse on Christianity. Daly undoubtedly contributed to the discussion on gender issues in the Christian faith, but her focus on androcentrism and her interpretations of Scripture led her to abandon the Christian faith. Mary Daly has written extensively on patriarchy as it is found in religion – particularly in the Christian faith – and how it filters through society. In her critique of patriarchy she set her course to dismantle the facade of a patriarchal and misogynistic God as the root of patriarchy. Daly did not see any positive qualities of the Christian faith and completely rejected other interpretations of a God whose person embraces both male and female qualities. Against this background I will evaluate Daly’s post-Christian feminist theological and philosophical paradigm. I propose that Daly has a quadripartite theological and philosophical paradigm wherein there are four main players. The ‘Who is who’ in Daly’s quadripartite patriarchal theological and philosophical paradigm are the patriarchal male, the patriarchal female, the patriarchal God and the biophilic woman.

  15. An upper bound on the size of m-ary t-sEC/AUED codes

    Institute of Scientific and Technical Information of China (English)

    ZHANG Peng-cheng; FU Fang-wei; CHANG Zu-ling

    2006-01-01

    Finding good upper bound for the size of m-ary t-symmetric error correcting codes (t-sEC/AUED codes) codes is the main problem in the coding theory of m-ary t-sEC/AUED codes. Based on the method of Lagrange multipliers, We shall derive an upper bound on the size of m-ary t-sEC/AUED in this paper. Some examples achieved this upper bound are also given in this paper.

  16. An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients

    Science.gov (United States)

    2017-06-09

    Charcot Marie Tooth Disease (CMT); Hereditary Sensory and Motor Neuropathy; Nerve Compression Syndromes; Tooth Diseases; Congenital Abnormalities; Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System

  17. Rocky Mountain Arsenal Timeline

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document details all of the major events having occurred at the Rocky Mountain Arsenal from it's establishment on May 2, 1942 up through the document's release...

  18. Landforms of High Mountains

    Directory of Open Access Journals (Sweden)

    Derek A. McDougall

    2016-05-01

    Full Text Available Reviewed: Landforms of High Mountains. By Alexander Stahr and Ewald Langenscheidt. Heidelberg, Germany: Springer, 2015. viii + 158 pp. US$ 129.99. Also available as an e-book. ISBN 978-3-642-53714-1.

  19. Rocky Mountain spotted fever

    Science.gov (United States)

    ... Mountain spotted fever is caused by the bacteria Rickettsia rickettsii (R. Rickettsii) , which is carried by ticks. ... Saunders; 2014:chap 212. Walker DH, Blaton LS. Rickettsia rickettsii and other spotted fever group rickettsiae (Rocky ...

  20. Diurnal variation of mountain waves

    Directory of Open Access Journals (Sweden)

    R. M. Worthington

    2006-11-01

    Full Text Available Mountain waves could be modified as the boundary layer varies between stable and convective. However case studies show mountain waves day and night, and above e.g. convective rolls with precipitation lines over mountains. VHF radar measurements of vertical wind (1990–2006 confirm a seasonal variation of mountain-wave amplitude, yet there is little diurnal variation of amplitude. Mountain-wave azimuth shows possible diurnal variation compared to wind rotation across the boundary layer.

  1. YUCCA MOUNTAIN SITE DESCRIPTION

    Energy Technology Data Exchange (ETDEWEB)

    A.M. Simmons

    2004-04-16

    The ''Yucca Mountain Site Description'' summarizes, in a single document, the current state of knowledge and understanding of the natural system at Yucca Mountain. It describes the geology; geochemistry; past, present, and projected future climate; regional hydrologic system; and flow and transport within the unsaturated and saturated zones at the site. In addition, it discusses factors affecting radionuclide transport, the effect of thermal loading on the natural system, and tectonic hazards. The ''Yucca Mountain Site Description'' is broad in nature. It summarizes investigations carried out as part of the Yucca Mountain Project since 1988, but it also includes work done at the site in earlier years, as well as studies performed by others. The document has been prepared under the Office of Civilian Radioactive Waste Management quality assurance program for the Yucca Mountain Project. Yucca Mountain is located in Nye County in southern Nevada. The site lies in the north-central part of the Basin and Range physiographic province, within the northernmost subprovince commonly referred to as the Great Basin. The basin and range physiography reflects the extensional tectonic regime that has affected the region during the middle and late Cenozoic Era. Yucca Mountain was initially selected for characterization, in part, because of its thick unsaturated zone, its arid to semiarid climate, and the existence of a rock type that would support excavation of stable openings. In 1987, the United States Congress directed that Yucca Mountain be the only site characterized to evaluate its suitability for development of a geologic repository for high-level radioactive waste and spent nuclear fuel.

  2. Magnetic anomaly patterns over crustal blocks of the King Edward VII Peninsula, Marie Byrd Land, West Antarctica

    Directory of Open Access Journals (Sweden)

    M. Spano

    2000-06-01

    Full Text Available Within the framework of the GITARA II project an aeromagnetic survey was performed during the GANOVEXVII expedition (1992/1993 over the King Edward VII Peninsula in northwestern Marie Byrd Land (West Antarctica. This region which may represent the eastern flank of the Ross Sea rift system had previously been explored only at reconnaissance level. New total field and upward continued (10 km magnetic anomaly maps are produced and interpreted here to map and discuss the crustal structure of the Edward VII Peninsula. Tworound-shaped, high-amplitude magnetic anomalies are recognised over the Alexandra Mountains block. The anomalies are difficult to interpret since susceptibility data indicate the prevalence of non-magnetic rocks at the surface. A possible interpretation is that the anomalies are due to Cretaceous mafic intrusives distinct from weakly magnetic Byrd Coast Granite of the adjacent Rockefeller Mountains block. Alternatively the anomalies could be related to buried pluton-sized Devonian Ford Granodiorite intruded by dikes. If Cretaceous in age, the former intrusives revealed from the magnetics could also be responsible for contact metamorphism of the adjacent Alexandra Mountains migmatites. Lower amplitude circular anomalies over the Central Plateau and Prestrud Inlet are likely to be caused by unexposed Devonian Ford Granodiorite which crops out in the Ford Ranges. Elongated high-frequency anomalies of the Sulzberger Bay are similar to those recognised over seismically constrained Cenozoic rift-related volcanics of the Ross Sea. A broad magnetic low over the Sulzberger Ice Shelf may be indicative of a fault bounded graben-like basin with sedimentary infill. Overall recognition of magnetic anomaly patterns and trends reveals segmentation of the Edward VII Peninsula and of the adjacent marine areas in distinct crustal blocks. Faults may separate these blocks and they are interpreted to reflect multiple Cretaceous and maybe Cenozoic crustal

  3. Mary Wakefield: Health Resources and Services Administrator. Interview.

    Science.gov (United States)

    Wakefield, Mary

    2014-06-01

    Dr. Mary Wakefield is the administrator of the Health Resources and Services Administration. She came from the University of North Dakota, where she directed the Center for Rural Health. She has served as director of the Center for Health Policy, Research and Ethics at George Mason University and has worked with the World Health Organization's Global Programme on AIDS in Geneva, Switzerland. She is a fellow in the American Academy of Nursing and was elected to the Institute of Medicine of the National Academies. A native of North Dakota, Wakefield holds a doctoral degree in nursing from the University of Texas.

  4. The ascent of Mary Somerville in 19th century society

    CERN Document Server

    Strickland, Elisabetta

    2016-01-01

    This biography traces the life and work of Mary Fairfax Somerville, whose extraordinary mathematical talent only came to light through fortuitous circumstances. Barely taught to read and write as a child, all the science she learned and mastered was self taught. In this delightful narrative the author takes up the challenge of discovering how Somerville came to be one of the most outstanding British women scientists and, furthermore, a popular writer. Particular attention is paid to the gender aspects of Somerville's success in what was, to put it mildly, a predominantly male domain.

  5. Uus kuum Eesti disain / Silvia Pärmann, Maris Takk

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2015-01-01

    Karl Tauli disainitud taburet "Ämblu", Aap Piho puidust ümmargune laud, Marit Ilisoni tekkmantlid kollektsioonist "Longing for Sleep/Magada tahaks", Narma vaibakollektsioon "OPEN 2015/16" (disainerid Monika Järg, Kaidi Ploomipuu), Annike Laigo vaibakollektsioon "XX", Kairi Katmanni vaip "Storytellers", Valhalla Factory kollektsiooni "Daydreamers" ripptool, Raili Keivi betoonist ja portselanist nõudekollektsioon, Tarmo Luisu valgusti "Kassett", Stella Soomlaisi käekotid, Karin Kallase ja Erik Pasti (Stuudio Nahk) disainitud jalatsid, käekotid ja ehted, Kuula + Jylhä jalatsikollektsioon, Mokoko (disainer Mari Maripuu) nahast aksessuaarid

  6. Uus kuum Eesti disain / Silvia Pärmann, Maris Takk

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2015-01-01

    Karl Tauli disainitud taburet "Ämblu", Aap Piho puidust ümmargune laud, Marit Ilisoni tekkmantlid kollektsioonist "Longing for Sleep/Magada tahaks", Narma vaibakollektsioon "OPEN 2015/16" (disainerid Monika Järg, Kaidi Ploomipuu), Annike Laigo vaibakollektsioon "XX", Kairi Katmanni vaip "Storytellers", Valhalla Factory kollektsiooni "Daydreamers" ripptool, Raili Keivi betoonist ja portselanist nõudekollektsioon, Tarmo Luisu valgusti "Kassett", Stella Soomlaisi käekotid, Karin Kallase ja Erik Pasti (Stuudio Nahk) disainitud jalatsid, käekotid ja ehted, Kuula + Jylhä jalatsikollektsioon, Mokoko (disainer Mari Maripuu) nahast aksessuaarid

  7. Charcot-Marie-Tooth病的特殊类型

    Institute of Scientific and Technical Information of China (English)

    马永才; 李太伟

    2003-01-01

    @@ Charcot-Marie-Tooth病(CMT)又名腓骨肌萎缩症或遗传性运动、感觉神经病(HMSN)是一组影响周围神经系统临床、亚临床的遗传多型性疾病.以首先出现腓骨肌萎缩,继以远端肌萎缩为特征,伴感觉障碍、脊柱及足畸形、植物神经功能紊乱等.

  8. Charcot-marie-tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2011-07-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  9. Charcot-Marie-Tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2012-02-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  10. Química Supramolecular amb Jean-Marie Lehn

    OpenAIRE

    2012-01-01

    "La química supramolecular pot ajudar a fer medicaments més eficaços". Amb motiu de les II Jornades Doctorals organitzades el passat juny des del Departament de Química de la UAB, el Premi Nobel de Química de l'any 1987 Jean-Marie Lehn va visitar la nostra universitat per impartir una xerrada sobre el disseny de nanoestructures supramoleculars i les seves aplicacions. Aprofitant aquesta visita, des d'UAB Divulga li vam realitzar una entrevista per saber més coses sobre la química supramolecul...

  11. Sister Mary Joseph Nodule as a Presenting Sign of Pancreatobiliary Adenocarcinoma

    OpenAIRE

    2012-01-01

    Sister Mary Joseph nodules represent metastatic cancer of the umbilicus. These malignancies are usually associated with the ovary and gastrointestinal tract. The authors report the case of a Sister Mary Joseph nodule originating from the bifurcation of the common hepatic duct. Umbilical nodules should prompt clinical evaluations, as these tumors are usually associated with poor prognosis.

  12. Sister Mary joseph nodule as a presenting sign of pancreatobiliary adenocarcinoma.

    Science.gov (United States)

    Shelling, Michael L; Vitiello, Magalys; Lanuti, Emma L; Rodriguez, Senen; Kerdel, Francisco A

    2012-10-01

    Sister Mary Joseph nodules represent metastatic cancer of the umbilicus. These malignancies are usually associated with the ovary and gastrointestinal tract. The authors report the case of a Sister Mary Joseph nodule originating from the bifurcation of the common hepatic duct. Umbilical nodules should prompt clinical evaluations, as these tumors are usually associated with poor prognosis.

  13. Potential Hosts for Lambertella corni-maris and Phacidium lacerum within the Family Rosaceae

    Science.gov (United States)

    Two fungi were described in 2015 and 2016 as pathogens of pome fruit in the Pacific Northwest USA: Lambertella corni-maris on apple (Malus domestica), and Phacidium lacerum (synonym, Ceuthospora pinastri) on apple and d’Anjou pear (Pyrus communis). We documented pathogenicity of L. corni-maris to d...

  14. Using the "Mary Tyler Moore Show" as a Feminist Teaching Tool

    Science.gov (United States)

    Jule, Allyson

    2010-01-01

    This paper explores the use of "The Mary Tyler Moore Show" as a teaching tool used with a group of final-year undergraduate students who gathered together last academic year (2007-8) to explore Women in Leadership, as part of a Communications course. The research focus was: How can the use of "The Mary Tyler Moore Show" (a 1970-7 American…

  15. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology

    CERN Multimedia

    Patrice Loiez

    2002-01-01

    Photo 0210006_07a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_14a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_22: Dr. David Plane (CERN) introducing Dr. Theodore Papazoglou from the European Commission. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellowships in the 6th Framework Programme". Photo 0210006_28a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN and Dept. of Physics, University of Milan. Addressing the Marie-Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellows Association". Photo 0210006_29a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN a...

  16. Foix-Chavany-Marie syndrome in a 17-year-old female with congenital cytomegalovirus infection.

    Science.gov (United States)

    Conforti, Renata; Capasso, Raffaella; Capaldo, Guglielmo; Dato, Clemente; Saracino, Dario; Di Iorio, Giuseppe; Melone, Mariarosa A

    2014-01-01

    Foix-Chavany-Marie syndrome is characterized by bilateral facio-glosso-pharyngo-masticatory paralysis of voluntary movement due to bilateral anterior opercular lesions. We describe the case of a 17-year-old female affected by Foix-Chavany-Marie syndrome and congenital cytomegalovirus infection, evaluating the possible etiopathogenetic correlation between cerebral cortical dysplasia and intrauterine infections.

  17. Quality-of-life in Charcot-Marie-Tooth disease: the patient's perspective.

    Science.gov (United States)

    Johnson, Nicholas E; Heatwole, Chad R; Dilek, Nuran; Sowden, Janet; Kirk, Callyn A; Shereff, Denise; Shy, Michael E; Herrmann, David N

    2014-11-01

    This study determines the impact of symptoms associated with Charcot-Marie-Tooth disease on quality-of-life. Charcot-Marie-Tooth patients in the Inherited Neuropathies Consortium Rare Diseases Clinical Research Network Contact Registry were surveyed. The survey inquired about 214 symptoms and 20 themes previously identified as important to Charcot-Marie-Tooth patients through patient interviews. Symptom population impact was calculated as the prevalence multiplied by the relative importance of each symptom identified. Prevalence and symptom impact were analyzed by age, symptom duration, gender, Charcot-Marie-Tooth type, and employment status. 407 participants returned the survey, identifying foot and ankle weakness (99.7%) and impaired balance (98.6%) as the most prevalent themes. Foot and ankle weakness and limitations with mobility were the themes with the highest impact. Both symptom prevalence and impact gradually increased with age and symptom duration. Several themes were more prevalent in women with Charcot-Marie-Tooth, including activity limitations, pain, fatigue, hip-thigh weakness, and gastrointestinal issues. All of the themes, except emotional or body image issues, were more prevalent among unemployed individuals. There were minimal differences in symptom prevalence between Charcot-Marie-Tooth types. There are multiple symptoms that impact Charcot-Marie-Tooth quality-of-life in adults. These symptoms have different levels of importance, are readily recognized by patients, and represent critical areas of Charcot-Marie-Tooth health. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Mari Kurismaa : "Kodu kujundamine vajab isiklikku põhjust" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Mari Kurismaa (sünd. 1956) värvide valikust, kodu kujundamisest, praegusest arhitektuurist ja sisearhitektuurist. Mari Kurismaast, autasud (2002. a. Mies van der Rohe preemia EALi-poolne nominent Jaak Huimerinna ja Indrek Saareperaga Järve Selveri projekti töögrupis). Ill.: neli värv. portreed M. Kurismaast

  19. Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy.

    NARCIS (Netherlands)

    Claeys, K.G.; Zuchner, S.; Kennerson, M.; Berciano, J.; Garcia, A.; Verhoeven, K.; Storey, E.; Merory, J.R.; Bienfait, H.M.; Lammens, M.M.Y.; Nelis, E.; Baets, J.; Vriendt, E. De; Berneman, Z.N.; Veuster, I. De; Vance, J.M.; Nicholson, G.; Timmerman, V.; Jonghe, P. de

    2009-01-01

    Dominant intermediate Charcot-Marie-Tooth neuropathy type B is caused by mutations in dynamin 2. We studied the clinical, haematological, electrophysiological and sural nerve biopsy findings in 34 patients belonging to six unrelated dominant intermediate Charcot-Marie-Tooth neuropathy type B familie

  20. "The Bravest of the Brave": A Conversation with Mary Bitterman and James Narduzzi

    Science.gov (United States)

    Continuing Higher Education Review, 2008

    2008-01-01

    This article presents an interview with Mary Bitterman and James Narduzzi. Mary Bitterman, former President and CEO of The James Irvine Foundation, is President of The Bernard Osher Foundation and Immediate Past Chairman of the Public Broadcasting Service (PBS). James Narduzzi is Dean of the University of Richmond's School of Continuing Studies.…

  1. Kalmer Poopuu sai esimese Mari Möldre nimelise preemia / Jaan Lukas

    Index Scriptorium Estoniae

    Lukas, Jaan, 1964-

    2008-01-01

    Jõgevamaal Tabiveres toimunud VIII eesti külateatrite festivalil Salme Vallateatri lavastuses "Kalevipoeg" Tuuslarit mänginud rolli eest pälvis Mari Möldre näitlejapreemia harrastusnäitleja Kalmer Poopuu. Mari Möldre näitlejapreemiat antakse välja esmakordselt, selle väljaandjaks on Tabivere vallavalitsus

  2. "Does Broca's Area Exist?:" Christofredo Jakob's 1906 Response to Pierre Marie's Holistic Stance

    Science.gov (United States)

    Tsapkini, Kyrana; Vivas, Ana B.; Triarhou, Lazaros C.

    2008-01-01

    In 1906, Pierre Marie triggered a heated controversy and an exchange of articles with Jules Dejerine over the localization of language functions in the human brain. The debate spread internationally. One of the timeliest responses, that appeared in print 1 month after Marie's paper, came from Christofredo Jakob, a Bavarian-born neuropathologist…

  3. Auto möirgab, ratas laulab / Mari Jüssi ; interv. Ylle Rajasaar

    Index Scriptorium Estoniae

    Jüssi, Mari, 1971-

    2008-01-01

    Uue Maailma Seltsi liige Mari Jüssi Eesti Rohelisest Liikumisest ja Uue Maailma Seltsist ka Tallinna linnaplaneerimisest, ühistranspordist, teede planeerimisest, valglinnastumisest, rattateedest, raudtee võimaluste vähesest kasutamisest. Mari Jüssi teemadeks on säästev transpordipoliitika ja autovaba linnaplaneerimine

  4. Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy

    NARCIS (Netherlands)

    K.G. Claeys; S. Züchner; M. Kennerson; J. Berciano; A. Garcia; K. Verhoeven; E. Storey; J.R. Merory; H.M.E. Bienfait; M. Lammens; E. Nelis; J. Baets; E. de Vriendt; Z.N. Berneman; I. de Veuster; J.M. Vance; G. Nicholson; V. Timmerman; P. de Jonghe

    2009-01-01

    Dominant intermediate Charcot-Marie-Tooth neuropathy type B is caused by mutations in dynamin 2. We studied the clinical, haematological, electrophysiological and sural nerve biopsy findings in 34 patients belonging to six unrelated dominant intermediate Charcot-Marie-Tooth neuropathy type B familie

  5. Kalmer Poopuu sai esimese Mari Möldre nimelise preemia / Jaan Lukas

    Index Scriptorium Estoniae

    Lukas, Jaan, 1964-

    2008-01-01

    Jõgevamaal Tabiveres toimunud VIII eesti külateatrite festivalil Salme Vallateatri lavastuses "Kalevipoeg" Tuuslarit mänginud rolli eest pälvis Mari Möldre näitlejapreemia harrastusnäitleja Kalmer Poopuu. Mari Möldre näitlejapreemiat antakse välja esmakordselt, selle väljaandjaks on Tabivere vallavalitsus

  6. Using the "Mary Tyler Moore Show" as a Feminist Teaching Tool

    Science.gov (United States)

    Jule, Allyson

    2010-01-01

    This paper explores the use of "The Mary Tyler Moore Show" as a teaching tool used with a group of final-year undergraduate students who gathered together last academic year (2007-8) to explore Women in Leadership, as part of a Communications course. The research focus was: How can the use of "The Mary Tyler Moore Show" (a…

  7. Road and Street Centerlines, St. Mary's County Centerlines, Published in 2002, 1:600 (1in=50ft) scale, St Mary's County Government.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — , published at 1:600 (1in=50ft) scale, was produced all or in part from Orthoimagery information as of 2002. It is described as 'St. Mary's County Centerlines'. Data...

  8. Mountain saved. is a mountain earned

    Energy Technology Data Exchange (ETDEWEB)

    Margolis, K.

    The Anaconda Copper Company boasted that the smokestack on its Washee smelter mill was the world's tallest. It also was probably the world's deadliest. Mysterious livestock deaths began occurring in 1906. They seemed to concentrate in the path of the prevailing westerly winds, carrying the Washee's smelter smoke plume toward Mt. Haggin. As evidence mounted that the deaths were connected to particulate fallout from the smelter (largely oxides of zinc, arsenic, lead, and copper), there were rumblings of lawsuits against Anaconda. The company felt threatened, but did not possess the technology to cure the situation. To protect itself, Anaconda purchased all the lands that were affected by fallout from the smelter smokestack. The result was the formation of the 154,000-acre Mt. Haggin Ranch. Today, the Anaconda Copper Company uses sophisticated pollution abatement equipment, and it is possible to see the healing that has taken place in recent years. The ranch includes rugged mountain peaks and ridges, high mountain valleys, and rolling foothills. A fisherman's paradise, the area also contains 20 mountain lakes, numerous ponds, and over 60 miles of trout streams. The Conservancy has been working to save Mt. Haggin since 1969. Negotiations have involved not only the fee owner--Mt. Haggin Livestock, Inc.--but also parties holding grazing and timber contracts, a variety of public agencies, and the Anaconda Company, which still holds some rights over the portion of the property not yet purchased by the Conservancy. The Conservancy assists in preserving lands like Mt. Haggin by handling the financial and legal aspects of land purchases. The Conservancy is allocating property to two ultimate recipients: the U.S. Forest Service and the montana Department of Fish and Game.

  9. A space radiation shielding model of the Martian radiation environment experiment (MARIE)

    Science.gov (United States)

    Atwell, W.; Saganti, P.; Cucinotta, F. A.; Zeitlin, C. J.

    2004-01-01

    The 2001 Mars Odyssey spacecraft was launched towards Mars on April 7, 2001. Onboard the spacecraft is the Martian radiation environment experiment (MARIE), which is designed to measure the background radiation environment due to galactic cosmic rays (GCR) and solar protons in the 20-500 MeV/n energy range. We present an approach for developing a space radiation-shielding model of the spacecraft that includes the MARIE instrument in the current mapping phase orientation. A discussion is presented describing the development and methodology used to construct the shielding model. For a given GCR model environment, using the current MARIE shielding model and the high-energy particle transport codes, dose rate values are compared with MARIE measurements during the early mapping phase in Mars orbit. The results show good agreement between the model calculations and the MARIE measurements as presented for the March 2002 dataset. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

  10. Marie Curie nurses: enabling patients with cancer to die at home.

    Science.gov (United States)

    Higginson, Irene J; Wilkinson, Susie

    2002-05-01

    Marie Curie Cancer Care established its nursing service in 1958; however, the service has had little formal evaluation. This study aimed to describe and evaluate the care provided by Marie Curie nurse, and in particular to determine whether patients in their care remained and died at home. Two existing data sets were used: data on all patients referred to the Marie Curie Nursing Services in 147 areas of England, Wales, Scotland and Northern Ireland for 26 months, and data on cancer death registrations in England. A request for a Marie Curie nurse was made for 26,632 patients, 97% of whom had cancer and 11% of whom lived alone. The amount of care provided varied enormously (Marie Curie nurses facilitated home death for many patients. Services need to ensure that mechanisms are in place to achieve data collection. Rigorous prospective evaluation is needed in the future.

  11. STRAWBERRY MOUNTAIN WILDERNESS, OREGON.

    Science.gov (United States)

    Thayer, T.P.; Stotelmeyer, Ronald B.

    1984-01-01

    The Strawberry Mountain Wilderness extends 18 mi along the crest of the Strawberry Range and comprises about 53 sq mi in the Malheur National Forest, Grant County, Oregon. Systematic geologic mapping, geochemical sampling and detailed sampling of prospect workings was done. A demonstrated copper resource in small quartz veins averaging at most 0. 33 percent copper with traces of silver occurs in shear zones in gabbro. Two small areas with substantiated potential for chrome occur near the northern edge of the wilderness. There is little promise for the occurrence of additional mineral or energy resources in the Strawberry Mountain Wilderness.

  12. Himalayan Mountain Range, India

    Science.gov (United States)

    1981-01-01

    Snow is present the year round in most of the high Himalaya Mountain Range (33.0N, 76.5E). In this view taken at the onset of winter, the continuous snow line can be seen for hundreds of miles along the south face of the range in the Indian states of Punjab and Kashmir. The snow line is at about 12,000 ft. altitude but the deep Cenab River gorge is easily delineated as a break along the south edge of the snow covered mountains. '

  13. Charcot-Marie-Tooth disease: genetic and rehabilitation aspects

    Directory of Open Access Journals (Sweden)

    Mariana CEVEI

    2008-05-01

    Full Text Available Charcot-Marie-Tooth hereditary motor and sensory neuropathy refers to a group of disorders characterized by a chronic motor and sensory polyneuropathy. Typical cases have distal muscle weakness and peroneal atrophy often associated with mild to moderate sensory loss, depressed tendon reflexes, and pes cavus. Hereditary neuropathies are categorized by mode of inheritance and chromosomal locus. The diagnosis is based on family history, characteristic findings on physical examination, EMG, nerve conduction velocity testing, and occasionally on nerve biopsy. The disorder shows allelic and non-allelic genetic heterogeneity, thus mutations of different genes leading to the same clinical features. Also, different mutations of the same gene may lead to different phenotypes. Molecular genetic testing is available in clinical laboratories for diagnosis of 7 subtypes of the disease. Genetic counseling and risk assessment depend on the inheritance. We present two cases with Charcot-Marie-Tooth type 1 and type 2 respectively. There is no cure for the disorder, although physical therapy and moderate activity are often recommended to maintain muscle strength and endurance.

  14. Angles of Refraction: The Letters of Mary Delany

    Directory of Open Access Journals (Sweden)

    Eleonora Chiavetta

    2014-04-01

    Full Text Available Mary Delany (1700-1788 is particularly famous for her paper-cuttings or ‘mosaicks’ based on botanical subjects. A very lively woman of fashion, she was close to Queen Charlotte and one of the Bluestocking Ladies. She left a vivid portrait of life and society in eighteenth century England and Ireland in the six volumes of her Autobiography and Letters, edited in 1861 by her descendant Lady Llanover. Her autobiography is made up of 18 letters sent to her most intimate friend, Margaret Cavendish, Duchess of Portland. The first letter is dated 1740, but in this, as in the following ones, Mrs. Delany narrates her past life to her friend, starting from the early years of her life, describing her unhappy marriage, financial difficulties as a widow, and family relationships. Along with these ‘autobiographical’ letters, other letters written by her to her sister Ann are introduced, which date to the periods of life Mrs. Delany is dealing with. The aim of this paper is to focus on the textual, linguistic and content differences between the two letter types, and analyse how the identity of Mary Delany is differently constructed and perceived in the explicit autobiographical letters addressed to the Duchess of Portland, and the ones written to her sister. 

  15. Marie Bonaparte, her first two patients and the literary world.

    Science.gov (United States)

    Amouroux, Rémy

    2010-08-01

    Marie Bonaparte (1882-1962) played a critical role in the development of psychoanalysis in France. Her clinical activity is not well known yet she was one of the first female French psychoanalysts. The journalist-writers Alice and Valerio Jahier were Bonaparte's first two patients. She conducted this dual analysis with Rudolph Loewenstein (1898-1976). Alice and Valerio exchanged analysts on several occasions. During his analysis, Valerio began corresponding with Italo Svevo (1861-1928), the author of La Coscienza di Zeno, who imparted his doubts on the therapeutic merits of psychoanalysis. Valerio described his difficult analysis in his letters to Svevo. Bonaparte consulted Freud on the subject, but was not able to prevent Valerio's suicide in 1939. The Princess of Greece encouraged Alice in her vocation as a writer and enabled her to benefit from her connections in literary circles. On the margins of this unpublished story of the two analyses, which is based on archived documents recently made available, we discover the importance of the links which were formed - around Marie Bonaparte - between psychoanalysis and literature. In addition to Italo Svevo, we come across the acerbic writer, Maurice Sachs, as well as the famous novelist, Stefan Zweig. Copyright © 2010 Institute of Psychoanalysis.

  16. Marie Nimier, au cœur du silence

    Directory of Open Access Journals (Sweden)

    Joëlle Papillon

    2012-01-01

    Full Text Available Dans La Reine du silence, Marie Nimier se confronte à la figure de son père, l’écrivain Roger Nimier, mort lorsqu’elle avait cinq ans. Elle y montre le poids qui pèse sur l’enfant d’écrivain, mais aussi celui de l’héritage du secret familial et de l’injonction au silence. La difficulté de l’élaboration de son récit de filiation se révèle dans les constants recommencements et reformulations, qui constituent la marque de la tension angoissante entre l’obligation de dire et celle de taire. In La Reine du silence, Marie Nimier confronts her father’s memory – the writer Roger Nimier, who died when she was five years old. The novel describes the burden of being a writer’s child, along with that of inheriting family secrets and submitting to a code of silence. The difficulty of recounting her relationship with her late father is evidenced by the narrator’s numerous “false starts” and her constant rewritings. The hesitant nature of the narration captures an anguish born of two irreconcilable obligations : the need to put things into words and the pressure to remain silent.

  17. Understand mountain studies from earthquake

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The Sichuan earthquake on 12 May was the most devastating one to hit China over the past 60 years or so. As the affected were mostly mountainous areas, serious damages were caused by various secondary disasters ranging from mountain collapse to the formation of quake lakes. This leaves Prof. DENG Wei, director-general of the Institute of Mountain Hazards and Environment, CAS, much to think about, and he is calling for strengthening studies on mountain science.

  18. Mountain-Plains Curriculum.

    Science.gov (United States)

    Mountain-Plains Education and Economic Development Program, Inc., Glasgow AFB, MT.

    The document lists the Mountain-Plains curriculum by job title (where applicable), including support courses. The curriculum areas covered are mathematics skills, communication skills, office education, lodging services, food services, marketing and distribution, welding support, automotive, small engines, career guidance, World of Work, health…

  19. Xiuhua Mountain Museum

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    XIUHUA Mountain Museum,a building nestled amongthe hills,is the first private museum of the Tujiaethnicity.Its name is an amalgamation of the names ofthe couple who run it,Gong Daoxiu and her husband ChenChuhua.According to Chen,the reason that he put his wife’s

  20. Digital mountains: toward development and environment protection in mountain regions

    Science.gov (United States)

    Jiang, Xiaobo

    2007-06-01

    Former studies on mountain system are focused on the department or subject characters, i.e. different department and branches of learning carry out researches only for their individual purposes and with individual characters of the subject of interests. As a whole, their investigation is lacking of comprehensive study in combination with global environment. Ecological environment in mountain regions is vulnerable to the disturbance of human activities. Therefore, it is a key issue to coordinate economic development and environment protection in mountain regions. On the other hand, a lot of work is ongoing on mountain sciences, especially depending on the application of RS and GIS. Moreover, the development of the Digital Earth (DE) provides a clue to re-understand mountains. These are the background of the emergence of the Digital Mountains (DM). One of the purposes of the DM is integrating spatial related data and information about mountains. Moreover, the DM is a viewpoint and methodology of understanding and quantifying mountains holistically. The concept of the DM is that, the spatial and temporal data related to mountain regions are stored and managed in computers; moreover, manipulating, analyzing, modeling, simulating and sharing of the mountain information are implemented by utilizing technologies of RS, GIS, GPS, Geo-informatic Tupu, computer, virtual reality (VR), 3D simulation, massive storage, mutual operation and network communication. The DM aims at advancing mountain sciences and sustainable mountain development. The DM is used to providing information and method for coordinating the mountain regions development and environment protection. The fundamental work of the DM is the design of the scientific architecture. Furthermore, construct and develop massive databases of mountains are the important steps these days.

  1. "Inhumanly brought back to life and misery": Mary Wollstonecraft, Frankenstein, and the Royal Humane Society.

    Science.gov (United States)

    Williams, C

    2001-01-01

    While thorough investigation of many aspects of contemporary scientific developments and Mary Shelley's personal history have provided illuminating contexts for the study of Frankenstein, the activities of the Royal Humane Society, and other bodies and individuals who pioneered and publicized resuscitation techniques, have been comparatively neglected. Here we find a richly documented, highly conspicuous area of scientific endeavour, which generated much excitement in life and literature from the last quarter of the eighteenth century onwards. There are three major points of contact with Frankenstein: Victor Frankenstein's revival of dead tissue to make his creature; the frequent occurrences of unconsciousness and asphyxia, both in the novel and in Mary Shelley's family during the period leading up to its composition, and the widely differing degrees of competence and success with which they are treated; and the possibility that resuscitative techniques were used to revive Mary Shelley's mother, Mary Wollstonecraft, after a suicide attempt. The impact on Frankenstein of Mary Shelley's lifelong distress at the role she played in bringing about her mother's death in childbirth has been thoroughly canvassed by other critics, notably Anne Mellor, but the thought that Mary Shelley, who was herself conceived after her mother's second suicide attempt, might be, in a sense, a child of the dead adds a further turn to the Gothic screw. This study traces a hitherto unexplored intersection between Mary Shelley's first novel and her family history, as well as showing how it launches a formidable attack on the shady ethics and inconsiderate arrogance of some early resuscitators.

  2. MaRIE: an experimental facility concept revolutionizing materials in extremes

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris W [Los Alamos National Laboratory

    2011-01-07

    The Matter-Radiation Interactions in Extremes (MaRIE) project intends to create an experimental facility that will revolutionize the control of materials in extremes. That control extends to extreme regimes where solid material has failed and begins to flow - the regimes of fluid dynamics and turbulent mixing. This presentation introduces the MaRIE facility concept, demonstrates examples of the science case that determine its functional requirements, and kicks-off the discussion of the decadal scientific challenges of mixing in extremes, including those MaRIE might address.

  3. Mary Seacole: self taught nurse and heroine of the Crimean War.

    Science.gov (United States)

    Harold, Ellis

    2009-09-01

    Mary Jane Seacole was born Mary Grant in Kingston Jamaica in 1805. Her father was a Scottish army officer and her mother a free Jamaican black, (slavery was not fully abolished in Jamaica until 1838). Her mother ran a hotel, Blundell Hall, in Kingston and was a traditional healer. Her skill as a nurse was much appreciated, as many of her residents were disabled British soldiers and sailors. It was from her mother that Mary learned the art of patient care, and she also assisted at the local British army hospital.

  4. Aspectos históricos da visita de Marie Sklodowska Curie a Belo Horizonte

    Directory of Open Access Journals (Sweden)

    Cássius Klay Nascimento

    2011-01-01

    Full Text Available In the year 2011 it is celebrated the Marie Sklodowska Curie Nobel Prize centenary and the International Year of Chemistry. However, it is not generally known that Marie Sklodowska Curie, one of the greatest scientists of all time, visited Belo Horizonte, state of Minas Gerais, Brazil. She arrived by train at Belo Horizonte city on 16 August 1926, coming from Rio de Janeiro and accompanied by her daughter Irène Joliot-Curie. The scientists visited the Institute of Radium of Belo Horizonte. The approach in this work emphasizes the presence of Marie Sklodowska Curie in Belo Horizonte, exploring the admiration and respect that people had for her.

  5. Mouse model for Charcot-Marie-Tooth as a tool to better understand the disease

    OpenAIRE

    Barneo Muñoz, Manuela

    2016-01-01

    Introducción La enfermedad de Charcot-Marie-Tooth (CMT) es uno de los trastornos neurológicos hereditarios más comunes que afecta a 17-40 de cada 100.000 personas según poblaciones; concretamente esta cifra se sitúa en 28 personas de cada 100.000 en España. La enfermedad recibe el nombre de los tres médicos que la identificaron por primera vez en 1886; Jean-Marie Charcot y Pierre Marie en París, Francia y Howard Henry Tooth en Cambridge, Inglaterra. La enfermedad de CMT, también conocida c...

  6. Mouse model for Charcot Marie-Tooth as a tool to better understand the disease

    OpenAIRE

    Barneo Muñoz, Manuela

    2016-01-01

    Introducción La enfermedad de Charcot-Marie-Tooth (CMT) es uno de los trastornos neurológicos hereditarios más comunes que afecta a 17-40 de cada 100.000 personas según poblaciones; concretamente esta cifra se sitúa en 28 personas de cada 100.000 en España. La enfermedad recibe el nombre de los tres médicos que la identificaron por primera vez en 1886; Jean-Marie Charcot y Pierre Marie en París, Francia y Howard Henry Tooth en Cambridge, Inglaterra. La enfermedad de CMT, también conocida c...

  7. MaRIE: Probing Dynamic Processes in Soft Materials Using Advanced Light Sources

    Energy Technology Data Exchange (ETDEWEB)

    Sykora, Milan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kober, Edward Martin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-16

    Los Alamos National Laboratory has developed a concept for a new research facility, MaRIE: Matter-Radiation Interactions in Extremes. The key motivation for MaRIE is to develop new experimental capabilities needed to fill the existing gaps in our fundamental understanding of materials important for key National Nuclear Security Agency (NNSA) goals. MaRIE will bring two major new capabilities: (a) the ability to characterize the meso- and microstructure of materials in bulk as well as local dynamic response characteristics, and (b) the ability to characterize how this microstructure evolves under NNSA-relevant conditions and impacts the material’s performance in this regime.

  8. The Representation of the Queen of France: Marie Antoinette from the Eighteenth Century till Now

    Institute of Scientific and Technical Information of China (English)

    牛声爽

    2015-01-01

    As an iconic historical character, Marie Antoinette as the Queen was loved and hated by the French people. She experi-enced a period of great prosperity during a revolutionary time in France. In this paper, we are going to explore how Marie Antoi-nette was painted in the eighteenth century and study the power dynamic within her court life. However, the portrait art can only de-picts people on the outside, no matter how vivid the portrait painted. Sofia Coppola, the American film director, made a film which gives us a new impression of Marie Antoinette from the inside out.

  9. Migration and Metamorphosis in Marie Ndiaye's Trois Femmes Puissantes

    Directory of Open Access Journals (Sweden)

    Deborah B. Gaensbauer

    2014-01-01

    Full Text Available In her 2009 Goncourt-Prize-winning novel, Trois femmes puissantes ( Three Strong Women, Marie Ndiaye experiments with a polyphonic, semi-fantastical rendering of identity-threatening displacements experienced by three women from different socio-geographic backgrounds. In a brief "Counterpoint" at the end of each of the novel's three sections--a narrative take on the musical technique employed by Ndiaye to introduce new focalizations and unexpected turns of events that complicate interpretations of the characters' behavior--each of the women is perceived as metamorphosed into a bird or a birdlike persona. This essay examines the innovative embedding of the shape-shifts in Trois femmes puissantes in both harrowing socio-political realities and the ambiguities of the fantastic and superstition to convey the dehumanizing, unequal power relations governing contemporary women's migration struggles.

  10. Noncompaction Cardiomyopathy with Charcot-Marie-Tooth Disease

    Directory of Open Access Journals (Sweden)

    Sherif Ali Eltawansy

    2015-01-01

    Full Text Available We report a case of a 53-year-old female presenting with a new-onset heart failure that was contributed secondary to noncompaction cardiomyopathy. The diagnosis was made by echocardiogram and confirmed by cardiac MRI. Noncompaction cardiomyopathy (also known as ventricular hypertrabeculation is a newly discovered disease. It is considered to be congenital (genetic cardiomyopathy. It is usually associated with genetic disorders and that could explain the genetic pathogenesis of the non-compaction cardiomyopathy. Our case had a history of Charcot-Marie-Tooth disease. There is a high incidence of arrhythmia and embolic complications. The treatment usually consists of the medical management, defibrillator placement, and lifelong anticoagulation. Heart transplantation will be the last resort.

  11. Therapeutic options in Charcot-Marie-Tooth diseases.

    Science.gov (United States)

    Mathis, Stéphane; Magy, Laurent; Vallat, Jean-Michel

    2015-04-01

    Charcot-Marie-Tooth (CMT) diseases represent a heterogeneous genetic disorder (more than 80 genes are implicated in these inherited neuropathies), but sharing a similar phenotype. In recent years, advances in molecular genetics and molecular biology, and also the development of various animal models of CMT, have led to a better understanding. Taken together, this knowledge represents a prerequisite for the development of future therapies in CMT, and in peripheral nervous system disorders in general. The efficacy of various substances has been shown in vitro and also in vivo (in animal models); but, no significant positive effect has yet been confirmed in humans. However, some of these trials are still in development, and we may expect positive results in the future. Although CMT is still an incurable disease, symptomatic treatments (physiotherapy, surgery, analgesic, etc.) are crucial to improve the quality of life of CMT patients.

  12. Mary Dorcey: The Poet’s Gaze and Scalpel

    Directory of Open Access Journals (Sweden)

    Maria Micaela Coppola

    2015-07-01

    Full Text Available Precision, vividness and colour characterise Mary Dorcey’s representations of individual and yet universal human experiences, such as love, loss, or grief. These are used like a surgeon’s scalpel: to frame, look inside, and closely observe sections of the individual’s body, and life. As we can see from the selection of poetic and prose texts presented here (alongside their translations into Italian, Dorcey cuts the skin of common definitions of private places and feelings (home, love, and grief. She looks at them from uncommon perspectives, bears witness to them, and gains insight from them. These and other issues are discussed in the interview, which is a revised version of a conversation that took place in Bologna (Italy in November 2014.

  13. Unilateral opercular infarction presenting with Foix-Chavany-Marie Syndrome.

    Science.gov (United States)

    Ohtomo, Ryo; Iwata, Atsushi; Tsuji, Shoji

    2014-01-01

    A 76-year-old man with a history of pontine, cerebellar infaction suddenly became speechless during the procedure of percutaneous coronary intervention. On examination, he was unable to close his mouth voluntarily, but spontaneous closing was preserved when smiling. He had anarthria and hypophonia, although his comprehension was preserved. He also had a severe dysphagia. Radiological studies revealed an acute stroke in the left anterior operculum, indicating Foix-Chavany-Marie Syndrome (FCMS) caused by a unilateral opercular lesion. Pathophysiology of the previous cases reported as unilateral FCMS remains controversial, but in our case, it could be delineated by the combination of the new lesion in the unilateral operculum and the old one in the contralateral pons. Since FCMS is not only related to biopercular lesions, we should consider thorough radiologic examination to clarify its anatomic basis.

  14. Mari Paz Corominas. "Sola en lugares de agua"

    OpenAIRE

    Asins, Consuelo

    1999-01-01

    Una canción suena en los tocadiscos de medio mundo; "sittin'on" (1). La voz que se escucha murió el año pasado. Otis Reding perdió la vida en un accidente de aviación sin saber que la última canción que grababa se convertiría en un su-per-ventas en 1968, y en un clásico que se alargaría hasta acariciar los oídos del 2000. 1968, México, Olimpiadas y Mari paz Corominas, la primera mujer española que consiguió llegar a una final olímpica en natación. Las hadas o las brujas quisieron que el 68 fu...

  15. Hand weakness in Charcot-Marie-Tooth disease 1X.

    LENUS (Irish Health Repository)

    Arthur-Farraj, P J

    2012-07-01

    There have been suggestions from previous studies that patients with Charcot-Marie-Tooth disease (CMT) have weaker dominant hand muscles. Since all studies to date have included a heterogeneous group of CMT patients we decided to analyse hand strength in 43 patients with CMT1X. We recorded handedness and the MRC scores for the first dorsal interosseous and abductor pollicis brevis muscles, median and ulnar nerve compound motor action potentials and conduction velocities in dominant and non-dominant hands. Twenty-two CMT1X patients (51%) had a weaker dominant hand; none had a stronger dominant hand. Mean MRC scores were significantly higher for first dorsal interosseous and abductor pollicis brevis in non-dominant hands compared to dominant hands. Median nerve compound motor action potentials were significantly reduced in dominant compared to non-dominant hands. We conclude that the dominant hand is weaker than the non-dominant hand in patients with CMT1X.

  16. The lives of Mary Foote: painter and Jungian.

    Science.gov (United States)

    Trousdell, Richard

    2016-11-01

    Mary Foote (1872-1968) was a successful early twentieth century American artist who suddenly closed her New York studio in 1926 to go to Zurich to study with Jung. There she joined his 'Interpretation of Visions' seminars (1930-1934), which she recorded and edited. This work won Jung's praise and his friendship, but all too often Foote was seen merely as a secretary or background figure. Deirdre Bair's biography of Jung suggested that Foote's life and work deserved fuller study, if only to rebalance our view of Jung's early women followers. This paper takes up that work to ask how Foote's early life and career led to her important work in preserving and describing Jung's earliest attempts to apply his theories to clinical practice. © 2016, The Society of Analytical Psychology.

  17. Klient/server aplikace hry mariáš

    OpenAIRE

    Fabian, Jaroslav

    2011-01-01

    Bakalářská práce popisuje návrh a implementaci karetní hry Mariáš. Hra je určená pro tři až čtyři hráče, kteří ji hrají přes počítačovou síť prostřednictvím protokolu TCP/IP. Hra je vytvořená pro systémy Microsoft Windows XP, Vista a 7 v programovacím jazyce Java. The bachelor s thesis describe predesign and implementation of the card game the Whisp. Game is dedicated for three or four players, who play it using computer network and protocol TCP/IP. Game is developed for Microsoft Win...

  18. Charcot-Marie-Tooth病的诊治%Progress of the diagnosis and treatment of Charcot-Marie-Tooth disease

    Institute of Scientific and Technical Information of China (English)

    洪道俊; 张玉生

    2014-01-01

    Charcot-Marie-Tooth病(CMT)是最常见的一种遗传性周围神经病,是一组具有显著临床异质性和遗传异质性的疾病,主要表现为肢体远端肌肉进行性无力和萎缩,伴有轻到中度感觉减退,腱反射减弱和足部畸形等.近20年CMT致病基因的不断被克隆,其疾病分型、临床表型和基因表型的关系发生了巨大变化.本文主要阐述CMT的疾病分型演变、基因诊断策略、临床治疗进展.

  19. Kirjanike aed Nõmme-Rahumäel / Elle-Mari Talivee

    Index Scriptorium Estoniae

    Talivee, Elle-Mari, 1974-

    2016-01-01

    Artur Adsoni ja Marie Underi Rahumäele Vabaduse puiestee ja Veere tänava nurgale ehitatud eramust (arhitekt Edgar Johan Kuusik) ning krundile rajatud iluaiast. Aastast 1944 elasid seal Friedebert ja Elo Tuglas

  20. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology.

    CERN Document Server

    Patrice Loiez

    2002-01-01

    Photo 0210008_05a: Dr, Rolf Landua (CERN) explaining to participants of the Marie Curie Workshop (held at CERN 3-4 October 2002) the ATHENA experiment and the Antiproton Decelerator. Photo 0210008_06a: Dr, Rolf Landua (CERN) explaining to participants of the Marie Curie Workshop (held at CERN 3-4 October 2002) the ATHENA experiment and the Antiproton Decelerator. Photo 0210008_08a: Dr, Rolf Landua (CERN) explaining to participants of the Marie Curie Workshop (held at CERN 3-4 October 2002) the ATHENA experiment and the Antiproton Decelerator. Photo 0210008_09a: Dr, Rolf Landua (CERN) explaining to participants of the Marie Curie Workshop (held at CERN 3-4 October 2002) the ATHENA experiment and the Antiproton Decelerator.

  1. Romance, recognition and revenge in Marie Clements's The Unnatural and Accidental Women

    National Research Council Canada - National Science Library

    Bamford, Karen

    2010-01-01

    This essay considers the relationship of Marie Clements's The Unnatural and Accidental Women to European traditions of drama and folk narrative, and especially its relation to the genres of revenge tragedy and romance...

  2. De novo PMP2 mutations in families with type 1 Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Motley, William W; Palaima, Paulius; Yum, Sabrina W; Gonzalez, Michael A; Tao, Feifei; Wanschitz, Julia V; Strickland, Alleene V; Löscher, Wolfgang N; De Vriendt, Els; Koppi, Stefan; Medne, Livija; Janecke, Andreas R; Jordanova, Albena; Zuchner, Stephan; Scherer, Steven S

    2016-06-01

    We performed whole exome sequencing on a patient with Charcot-Marie-Tooth disease type 1 and identified a de novo mutation in PMP2, the gene that encodes the myelin P2 protein. This mutation (p.Ile52Thr) was passed from the proband to his one affected son, and segregates with clinical and electrophysiological evidence of demyelinating neuropathy. We then screened a cohort of 136 European probands with uncharacterized genetic cause of Charcot-Marie-Tooth disease and identified another family with Charcot-Marie-Tooth disease type 1 that has a mutation affecting an adjacent amino acid (p.Thr51Pro), which segregates with disease. Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie-Tooth disease type 1. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Igal mõisal on oma lugu / Mari-Ann Remmel

    Index Scriptorium Estoniae

    Remmel, Mari-Ann

    2008-01-01

    Kirjastuselt "Tänapäev" ilmus raamat "Mõisalegendid. Harjumaa", koostaja Mari-Ann Remmel, kujundaja Angelika Schneider. Kogumik sisaldab ka ajaloolist ning genealoogilist teavet mõisahoonete ning -omanike kohta

  4. The Mesoscale Science of the Matter-Radiation Interactions in Extremes (MaRIE) project

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Donald Raymond [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-17

    The National Nuclear Security Administration (NNSA) requires the ability to understand and test how material structures, defects, and interfaces determine performance in extreme environments such as in nuclear weapons. To do this, MaRIE will be an x-ray source that is laser-like and brilliant with very fl exible and fast pulses to see at weapons-relevant time scales, and with high enough energy to study critical materials. The Department of Energy (DOE) has determined there is a mission need for MaRIE to deliver this capability. MaRIE can use some of the existing infrastructure of the Los Alamos Neutron Science Center (LANSCE) and its accelerator capability. MaRIE will be built as a strategic partnership of DOE national laboratories and university collaborators.

  5. Mary Shelley's Frankenstein and Bram Stoker's Dracula: gender and science in literature

    National Research Council Canada - National Science Library

    de La Rocque, L

    2001-01-01

    .... In the present work, through a comparative analysis of two important literary works from the 19th century, Frankenstein, by Mary Shelley, and Dracula, by Bram Stoker, the issues concerning the view...

  6. Tarvo Hanno Varres, Mari-Leen Kiipli / Merilin Talumaa, Hanno Soans, Tatjana Kozlova-Johannes

    Index Scriptorium Estoniae

    Talumaa, Merilin, 1986-

    2015-01-01

    Vaatluse alla on võetud Tarvo Hanno Varrese heli- ja videoinstallatsioon "Lindistav põrand" (2015) ja heli- ja videoteos "Betweenland" (2014) ning Mari-Leen Kiipli fotoseeria "The school of dreams" (2012-2015)

  7. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  8. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  9. Marie-Pierre Lassus, Gaston Bachelard musicien. Une philosophie des silences et des timbres

    OpenAIRE

    Marida Rizzuti

    2012-01-01

    Marie-Pierre Lassus, Gaston Bachelard musicien. Une philosophie des silences et des timbres (Villeneuve d’Ascq, Presses Universitaires du Septentrion, 2010, 268 pp. ISBN: 978-275-740-1613) di     Marida Rizzuti

  10. Robert Bresson, Mariano Barroso, Paskaljevich, Mary Harron, David Trueba, Lars von Trier, Liv Ullmann, Zhang Yimou

    OpenAIRE

    La madriguera

    2000-01-01

    La madriguera (2000). Robert Bresson, Mariano Barroso, Paskaljevich, Mary Harron, David Trueba, Lars von Trier, Liv Ullmann, Zhang Yimou. Ediciones de intervención cultural S.L. http://hdl.handle.net/10251/41911. 80 80 33

  11. On the Turn of Two Millennia (60 Years of the Mari Archaeological Expedition

    Directory of Open Access Journals (Sweden)

    Nikitin Valeriy V.,

    2017-03-01

    Full Text Available The article is dedicated to the 60th Anniversary of the Mari Archaeological Expedition and summarizes the two decades of its studies (1996-2016 into the early cultures of the Mari region, starting from the era of the original settlement (Mesolithic, through the Neolithic-Eneolithic, Bronze Age, Early Iron Age and up to the Middle Ages. The expedition studied stations and settlements of primitive cultures, as well as unfortified and fortified settlements and necropolises. Special studies focused on formation and development of the early Mari culture, as well as the material and spiritual culture of the medieval Mari. The expedition continues its survey exploration in order to identify new archaeological sites. During the reported period, twelve monographs were published and three monographs prepared based on the expedition’s materials.

  12. Õpingud Humboldti Ülikoolis / Mari Laanemets ; intervjueerinud Heie Treier

    Index Scriptorium Estoniae

    Laanemets, Mari, 1975-

    2009-01-01

    Intervjuus Mari Laanemetsaga on teemaks tema õpingud Humboldti Ülikoolis, sealse kunstiteaduse ja õppe lähtekohad ja võimalik erinevus siinsest kunstiteadusest, tema doktoritöö 1970. aastate kunstist

  13. 77 FR 49719 - Amendment of Class D Airspace; Sault Ste Marie, ON

    Science.gov (United States)

    2012-08-17

    ... control zone over Sault Ste Marie Airport. The FAA is taking this action to enhance the safety and..., creating additional controlled airspace to coincide with that portion of the control zone in...

  14. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2003-01-01

    Concordia Ülikooli rektor Mart Susi esitas kohtule avalduse, milles taotleb ülikooli pidanud Concordia Varahalduse OÜ pankroti väljakuulutamist. Vt. samas: Mari-Ann Susi õigustas ülikooli raha kasutamist

  15. Ooperi valem : Mari Vihmandi "Armastuse valem" / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  16. Ämaris asuvad hävitajad lendavad täies relvis

    Index Scriptorium Estoniae

    2016-01-01

    Ämari õhubaasis asuvad Saksa õhujõudude hävitajad Eurofighter Typhoon on Ukraina konflikti tõttu varustatud täieliku lahingrelvastusega, hävitajatel on lühi-ja keskmaaraketid, kirjutab Spiegel

  17. Mediated Career Education at the Marie H. Katzenbach School for the Deaf

    Science.gov (United States)

    Lenox, James; Hamilton, Ronald

    1973-01-01

    A comprehensive career education program which uses varieties of audiovisual aids for aurally handicapped students, 4 through 21 years of age, at the Marie H. Katzenbach School for the Deaf is described. (MC)

  18. Igal mõisal on oma lugu / Mari-Ann Remmel

    Index Scriptorium Estoniae

    Remmel, Mari-Ann

    2008-01-01

    Kirjastuselt "Tänapäev" ilmus raamat "Mõisalegendid. Harjumaa", koostaja Mari-Ann Remmel, kujundaja Angelika Schneider. Kogumik sisaldab ka ajaloolist ning genealoogilist teavet mõisahoonete ning -omanike kohta

  19. A Study of Mrs.Gaskell’s Feminism in Mary Barton

    Institute of Scientific and Technical Information of China (English)

    甄艳华; 屈伟丽

    2015-01-01

    Mrs.Gaskel is one of the most outstanding feminist novelists in Victorian Age.Mary Barton is her first novel and the most important one deal with many subjects include the labor conflicts,ethical concerns as wel as the struggle for women rights.The paper tries to analyze Mary Barton from the feminist ’ s perspective and study Mrs.Gaskel ’s feminism through the analysis of the main characters in the novel.

  20. The Struggle for Human Betterment as A theme in Mary Shelly's Frankenstein

    Institute of Scientific and Technical Information of China (English)

    金丽华

    2006-01-01

    Men struggle for human betterment for over thousands of years. In Mary Shelley' s Frankenstein, there are many heroes who struggle for human betterment, such as Frankenstein, the Modern Prometheus, Walton, and even the monster,etc. The better we live today the higher aims we want to reach in the future. In this Gothic novel, Mary Shelley shows her idea of the creation of life and the consequence of it. Some of her descriptions reflect her opinion.

  1. The seminal role played by Pierre Marie in Neurology and Internal Medicine

    Directory of Open Access Journals (Sweden)

    Gustavo M Almeida

    2015-10-01

    Full Text Available The authors review the most important contributions of Pierre Marie to the elucidation and description of several neurological diseases, such as Charcot-Marie-Tooth’s disease and hereditary cerebellar ataxia, as well as his contributions to Internal Medicine, including his pioneering studies on acromegaly, ankylosing spondylitis, and hypertrophic pulmonary osteoarthropathy. His works led to incontestable advances in the medical sciences that transcended his time.

  2. Magical Realism in Mary Gavell’s Short Story The Swing

    Institute of Scientific and Technical Information of China (English)

    LI Ya-li

    2016-01-01

    The Swing, written by Mary Gavell, relates the pain of an aging mother, who is comforted by her childhood son’s re-turning to the family swing at night. The story is mixed with magic and reality, filled with magic symbols and implied with magi-cal feminism themes. By employing magical realism, Mary Gavell portrays the loneliness of an elder woman and creates for her a magical world where she could freely express herself.

  3. Unfashioned creatures, but half made up: Beginning with Mary Shelley's Spectre

    OpenAIRE

    2007-01-01

    This paper uses Derrida’s work Politics of Friendship to interrogate the concept of the “friend” in the educational and fictional writings of Mary Shelley, William Godwin and Mary Wiollstonecraft. It concludes with a reading of A Vindication of the Rights of Woman, which argues that a certain wager on the possibility friendship rhetorically structures Wollstonecraft’s text. The argument about friendship and education mounted in this paper leads on to my account of what elsewhere I have called...

  4. Patient-centred mountain medicine.

    Science.gov (United States)

    Szawarski, Piotr; Hillebrandt, David

    2016-08-01

    Venturing into the mountains, doctors have accompanied expeditions to provide routine care to the teams, undertake research and occasionally take on a rescue role. The role of doctors practicing mountain medicine is evolving. Public health issues involving concepts of health and safety have become necessary with the coming of commercial and youth expeditions. Increasingly individuals with a disability or a medical diagnosis choose to ascend to high altitudes. Doctors become involved in assessment of risk and providing advice for such individuals. The field of mountain medicine is perhaps unique in that acceptance of risk is part of the ethos of climbing and adventure. The pursuit of mountaineering goals may represent the ultimate conquest of a disability. Knowledge of mountain environment is essential in facilitating mountain ascents for those who choose to undertake them, in spite of a disability or medical condition.

  5. HENDUAN MOUNTAINS A Dazzling World

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The Indian Continent drifted northward and eventually collideawith the Euro-Asian Continent,pushing up the piece of land weknow today as the Himalayas and Henduan Mountains.Located where Qinghai,Tibet,Yunnan and Sichuan all meet.Asia,including the Nujiang,Jinshajiang and Lancanjiang.In the mountains,rivers Wave a drop of about 2,500 meters.Late last year,we drove into the mountainous area,covering adistance of some 1,000 km.

  6. X-linked Charcot-Marie-Tooth disease predominates in a cohort of multiethnic Malaysian patients.

    Science.gov (United States)

    Shahrizaila, Nortina; Samulong, Sarimah; Tey, Shelisa; Suan, Liaw Chiew; Meng, Lao Kah; Goh, Khean Jin; Ahmad-Annuar, Azlina

    2014-02-01

    Data regarding Charcot-Marie-Tooth disease is lacking in Southeast Asian populations. We investigated the frequency of the common genetic mutations in a multiethnic Malaysian cohort. Patients with features of Charcot-Marie-Tooth disease or hereditary liability to pressure palsies were investigated for PMP22 duplication, deletion, and point mutations and GJB1, MPZ, and MFN2 point mutations. Over a period of 3 years, we identified 25 index patients. A genetic diagnosis was reached in 60%. The most common were point mutations in GJB1, accounting for X-linked Charcot-Marie-Tooth disease (24% of the total patient population), followed by PMP22 duplication causing Charcot-Marie-Tooth disease type 1A (20%). We also discovered 2 novel GJB1 mutations, c.521C>T (Proline174Leucine) and c.220G>A (Valine74Methionine). X-linked Charcot-Marie-Tooth disease was found to predominate in our patient cohort. We also found a better phenotype/genotype correlation when applying a more recently recommended genetic approach to Charcot-Marie-Tooth disease. Copyright © 2013 Wiley Periodicals, Inc.

  7. Key issues for mountain areas

    National Research Council Canada - National Science Library

    Price, Martin F; Jansky, Libor; Iatsenia, Andrei A

    2004-01-01

    ... and livelihood opportunities . . . ... Safdar Parvez and Stephen F. Rasmussen 86 6 Mountain tourism and the conservation of biological and cultural diversity... Wendy Brewer Lama and Nikhat Sattar 11...

  8. A Breath of Mountain Air

    Institute of Scientific and Technical Information of China (English)

    YU LINTAO

    2011-01-01

    Mountains are everywhere,and rivers flow in almost every valley.This is the Qinling Mountains,a major eastto-west range in southern Shaanxi Province,bordering Hubei and Henan provinces.Because of its huge forest coverage,the Qinling Mountains are also known as one of the lungs of China.Expectations for travelling are changing in China as the lifestyle of city dwellers has become fast-paced and demanding.That provides the Qirding Mountain area a great opportunity to develop leisure tourism.

  9. Genetic epidemiology of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Braathen, G J

    2012-01-01

    Charcot-Marie-Tooth disease (CMT) is the most common inherited disorder of the peripheral nervous system. The frequency of different CMT genotypes has been estimated in clinic populations, but prevalence data from the general population is lacking. Point mutations in the mitofusin 2 (MFN2) gene has been identified exclusively in Charcot-Marie-Tooth disease type 2 (CMT2), and in a single family with intermediate CMT. MFN2 point mutations are probably the most common cause of CMT2. The CMT phenotype caused by mutation in the myelin protein zero (MPZ) gene varies considerably, from early onset and severe forms to late onset and milder forms. The mechanism is not well understood. The myelin protein zero (P(0) ) mediates adhesion in the spiral wraps of the Schwann cell's myelin sheath. X-linked Charcot-Marie Tooth disease (CMTX) is caused by mutations in the connexin32 (cx32) gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions. Estimate prevalence of CMT. Estimate frequency of Peripheral Myelin Protein 22 (PMP22) duplication and point mutations, insertions and deletions in Cx32, Early growth response 2 (EGR2), MFN2, MPZ, PMP22 and Small integral membrane protein of lysosome/late endosome (SIMPLE) genes. Description of novel mutations in Cx32, MFN2 and MPZ. Description of de novo mutations in MFN2. Our population based genetic epidemiological survey included persons with CMT residing in eastern Akershus County, Norway. The participants were interviewed and examined by one geneticist/neurologist, and classified clinically, neurophysiologically and genetically. Two-hundred and thirty-two consecutive unselected and unrelated CMT families with available DNA from all regions in Norway were included in the MFN2 study. We screened for point mutations in the MFN2 gene. We describe four novel mutations, two in the connexin32 gene and two in the MPZ gene. A total of 245 affected from 116 CMT families from the general population of eastern

  10. Phenotypic Variability of Childhood Charcot-Marie-Tooth Disease.

    Science.gov (United States)

    Cornett, Kayla M D; Menezes, Manoj P; Bray, Paula; Halaki, Mark; Shy, Rosemary R; Yum, Sabrina W; Estilow, Timothy; Moroni, Isabella; Foscan, Maria; Pagliano, Emanuela; Pareyson, Davide; Laurá, Matilde; Bhandari, Trupti; Muntoni, Francesco; Reilly, Mary M; Finkel, Richard S; Sowden, Janet; Eichinger, Katy J; Herrmann, David N; Shy, Michael E; Burns, Joshua

    2016-06-01

    Disease severity of childhood Charcot-Marie-Tooth disease (CMT) has not been extensively characterized, either within or between types of CMT to date. To assess the variability of disease severity in a large cohort of children and adolescents with CMT. A cross-sectional study was conducted among 520 children and adolescents aged 3 to 20 years at 8 universities and hospitals involved in the Inherited Neuropathies Consortium between August 6, 2009, and July 31, 2014, in Australia, Italy, the United Kingdom, and the United States. Data analysis was conducted from August 1, 2014, to December 1, 2015. Scores on the Charcot-Marie-Tooth Disease Pediatric Scale (CMTPedS), a well-validated unidimensional clinical outcome measure to assess disease severity. This instrument includes 11 items assessing fine and gross motor function, sensation, and balance to produce a total score ranging from 0 (unaffected) to 44 (severely affected). Among the 520 participants (274 males) aged 3 to 20 years, CMT type 1A (CMT1A) was the most prevalent type (252 [48.5%]), followed by CMT2A (31 [6.0%]), CMT1B (15 [2.9%]), CMT4C (13 [2.5%]), and CMTX1 (10 [1.9%]). Disease severity ranged from 1 to 44 points on the CMTPedS (mean [SD], 21.5 [8.9]), with ankle dorsiflexion strength and functional hand dexterity test being most affected. Participants with CMT1B (mean [SD] CMTPedS score, 24.0 [7.4]), CMT2A (29.7 [7.1]), and CMT4C (29.8 [8.6]) were more severely affected than those with CMT1A (18.9 [7.7]) and CMTX1 (males: 15.3 [7.7]; females: 13.0 [3.6]) (P disease severity. These results highlight the phenotypic variability within CMT genotypes and mutation-specific manifestations between types. This study has identified distinct functional limitations and self-reported impairments to target in future therapeutic trials.

  11. "Christ is the Mountain"

    Directory of Open Access Journals (Sweden)

    Carl Hallencreutz

    1979-01-01

    Full Text Available In this paper the author focuses on the religious function of symbols in the encounter and interaction of Christianity and other religions. Some observations on the religious function of the symbol of the Holy Mountain in different African contexts are presented. These contexts are a traditional Kikuyu religion, b a Christian hymn from Northern Tanzania, and c the New Year's Fiest of the independent Nazaretha Church among Zulu in South Africa. The examples of how the symbol of the holy mountain is used in different religious contexts in Africa are, of course, too limited to provide a basis for far-reaching generalizations on how symbols function religiously in the encounter of Christianity and other religions. However, this kind of analysis can be applied also when studying other encounters of religions inside and outside Africa. The symbol functions both as a carrier of a new religious message and as an indigenous means to appropriate this message locally and give it adequate form in different milieus. The symbols, which most likely have the religious functions are those which are of a general nature; light, way, living water, and which some are tempted to speak of as archetypes. Yet the comparison between the Chagga-hymn to the holy mountain and Shembe's interpretation of the blessing of the New Year's Fiest on Inhlangakozi indicates, that in the encounter of Christianity and other religions it is not only the symbols as such which produce the local appropriation of the new religious message and give it adequate localized form. Not even in the encounter of Christianity and other religions the symbols function religiously without human beings as actors in the historical process.

  12. Human impacts to mountain streams

    Science.gov (United States)

    Wohl, Ellen

    2006-09-01

    Mountain streams are here defined as channel networks within mountainous regions of the world. This definition encompasses tremendous diversity of physical and biological conditions, as well as history of land use. Human effects on mountain streams may result from activities undertaken within the stream channel that directly alter channel geometry, the dynamics of water and sediment movement, contaminants in the stream, or aquatic and riparian communities. Examples include channelization, construction of grade-control structures or check dams, removal of beavers, and placer mining. Human effects can also result from activities within the watershed that indirectly affect streams by altering the movement of water, sediment, and contaminants into the channel. Deforestation, cropping, grazing, land drainage, and urbanization are among the land uses that indirectly alter stream processes. An overview of the relative intensity of human impacts to mountain streams is provided by a table summarizing human effects on each of the major mountainous regions with respect to five categories: flow regulation, biotic integrity, water pollution, channel alteration, and land use. This table indicates that very few mountains have streams not at least moderately affected by land use. The least affected mountainous regions are those at very high or very low latitudes, although our scientific ignorance of conditions in low-latitude mountains in particular means that streams in these mountains might be more altered than is widely recognized. Four case studies from northern Sweden (arctic region), Colorado Front Range (semiarid temperate region), Swiss Alps (humid temperate region), and Papua New Guinea (humid tropics) are also used to explore in detail the history and effects on rivers of human activities in mountainous regions. The overview and case studies indicate that mountain streams must be managed with particular attention to upstream/downstream connections, hillslope

  13. Charcot-Marie-Tooth Disease Type 2B

    Directory of Open Access Journals (Sweden)

    Şenay Durdu

    2009-06-01

    Full Text Available Chatcot-Marie-Tooth (CMT is also known as peroneal muscular atrophy and hereditary motor-sensory neuropathy (HMSN. It is the most commonly encountered inherited peripheral neuropathy. Actually, CMT is not a single disease, but is a group of disorders with similar symptoms. CMT type 2 is the second most common form after CMT type1. Symptoms usually begin in childhood or early adulthood. Mostly the peripheral nerves of the lower extremities and occasionaly upper extremities may be affected. Motor nerve involvoment induces distal muscle weakness and atrophy in the lower extremities that may result in foot deformities known as foot drop, pes cavus, pes planus, hammer toe etc. As a result of sensorial nevre degeneration, callus, recurrent foot ulcers, osteonecrosis, osteolysis and spontaneous amputation may accompany the disease. The speed of nerve conduction is not changed in the EMG, but axonal type sensorymotor semptoms that lead to a decrease of amplitude. We report here a 55 year old man with recurrent foot ulcers for 33 years and self amputations, whose EMG findings suggest acsonal neuropathy and who also has a 20 year - old son with similar complaints.

  14. Mariátegui y las antinomias del indigenismo

    Directory of Open Access Journals (Sweden)

    Fernanda Beigel

    2001-01-01

    Full Text Available En este trabajo nos proponemos efectuar un recorrido que dé cuenta, por una parte, de la significación actual del “indigenismo” en el campo intelectual latinoamericano y, por otra, de las polémicas ocurridas en los años veinte, para revisar el marco en el que se desenvolvió el pensamiento y la praxis “indigenista” de José Carlos Mariátegui. Luego de un balance de los principales trazos de las más viejas y más nuevas discusiones que rodean la categoría de “indigenismo”, intentamos examinar la presencia de la herencia andina en el proyecto de socialismo indo-americano esbozado por el Amauta peruano. Especialmente, abordamos críticamente las relaciones existentes entre este proyecto de cambio social y los contornos de una racionalidad distinta, que parece haber nacido de nuestras entrañas y recién ahora estamos empezando a vislumbrar.

  15. The shifting paradigm of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Echaniz-Laguna, A

    2015-01-01

    Molecular studies have created a paradigm shift in our perception of Charcot-Marie-Tooth disease (CMT). Indeed, CMT has evolved from the concept of a rather homogeneous hereditary disease exclusively involving peripheral nerves to the concept of a highly heterogeneous clinical and genetic syndrome mainly - but sometimes not exclusively - involving the peripheral nervous system. The phenotypic spectrum of CMT overlaps with other inherited neuropathies such as distal hereditary motor neuropathy (dHMN), hereditary sensory and autonomic neuropathy (HSAN), spinal muscular atrophy (SMA) subtypes, and the neuropathies of mitochondrial disorders. At a molecular level, mutations in one given gene may alternatively provoke CMT, HSAN, dHMN or SMA variants. Over the last years, there have been dramatic advances in deciphering the molecular basis for many CMT subtypes and more than 900 different mutations in more than 60 causative genes are now described. However, as 75% of CMT causative genes apparently remain unknown and as disease-specific therapies are not available, major advances are yet to come in the field of CMT. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  16. Systematic review of exercise for Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Sman, Amy D; Hackett, Daniel; Fiatarone Singh, Maria; Fornusek, Ché; Menezes, Manoj P; Burns, Joshua

    2015-12-01

    Charcot-Marie-Tooth disease (CMT) is a slowly progressive hereditary degenerative disease and one of the most common neuromuscular disorders. Exercise may be beneficial to maintain strength and function for people with CMT, however, no comprehensive evaluation of the benefits and risks of exercise have been conducted. A systematic review was completed searching numerous electronic databases from earliest records to February 2015. Studies of any design including participants of any age with confirmed diagnosis of CMT that investigated the effects of exercise were eligible for inclusion. Of 13,301 articles identified following removal of duplicates, 11 articles including 9 unique studies met the criteria. Methodological quality of studies was moderate, sample sizes were small, and interventions and outcome measures used varied widely. Although the majority of the studies identified changes in one or more outcome measurements across exercise modalities, the majority were non-significant, possibly due to Type II errors. Significant effects described included improvements in strength, functional activities, and physiological adaptations following exercise. Despite many studies showing changes in strength and function following exercise, findings of this review should be met with caution due to the few studies available and moderate quality of evidence. Well-powered studies, harmonisation of outcome measures, and clearly described interventions across studies would improve the quality and comparability of the evidence base. The optimal exercise modality and intensity for people with CMT as well as the long-term safety of exercise remain unclear. © 2015 Peripheral Nerve Society.

  17. Municipio Mariño Estado Nueva Esparta

    Directory of Open Access Journals (Sweden)

    María Medina

    2008-01-01

    Full Text Available Se caracteriza la gastronomía típica margariteña como atractivo turístico del Municipio Mariño, sus componentes: restaurantes, autores, platos y promoción. Para formular recomendaciones que permitan su aprovechamiento. Los fundamentos teóricos se basan en el área turismo y gastronomía, y su importancia para la actividad. La metodología es descriptiva y su diseño es de campo. Como conclusión se tiene que la situación actual de la gastronomía típica margariteña como atractivo turístico del municipio se caracteriza por la falta de información y promoción, la cual no se está aprovechando como atractivo turístico debido a la falta de conocimiento sobre la gastronomía típica margariteña y donde además en los restaurantes del municipio se están modificando las recetas originales.

  18. Charcot-Marie-Tooth disease and intracellular traffic.

    Science.gov (United States)

    Bucci, Cecilia; Bakke, Oddmund; Progida, Cinzia

    2012-12-01

    Mutations of genes whose primary function is the regulation of membrane traffic are increasingly being identified as the underlying causes of various important human disorders. Intriguingly, mutations in ubiquitously expressed membrane traffic genes often lead to cell type- or organ-specific disorders. This is particularly true for neuronal diseases, identifying the nervous system as the most sensitive tissue to alterations of membrane traffic. Charcot-Marie-Tooth (CMT) disease is one of the most common inherited peripheral neuropathies. It is also known as hereditary motor and sensory neuropathy (HMSN), which comprises a group of disorders specifically affecting peripheral nerves. This peripheral neuropathy, highly heterogeneous both clinically and genetically, is characterized by a slowly progressive degeneration of the muscle of the foot, lower leg, hand and forearm, accompanied by sensory loss in the toes, fingers and limbs. More than 30 genes have been identified as targets of mutations that cause CMT neuropathy. A number of these genes encode proteins directly or indirectly involved in the regulation of intracellular traffic. Indeed, the list of genes linked to CMT disease includes genes important for vesicle formation, phosphoinositide metabolism, lysosomal degradation, mitochondrial fission and fusion, and also genes encoding endosomal and cytoskeletal proteins. This review focuses on the link between intracellular transport and CMT disease, highlighting the molecular mechanisms that underlie the different forms of this peripheral neuropathy and discussing the pathophysiological impact of membrane transport genetic defects as well as possible future ways to counteract these defects.

  19. Princess Marie Bonaparte, Edgar Allan Poe, and psychobiography.

    Science.gov (United States)

    Warner, S L

    1991-01-01

    Princess Marie Bonaparte was a colorful yet mysterious member of Freud's inner circle of psychoanalysis. In analysis with Freud beginning in 1925 (she was then 45 years old), she became a lay analyst and writer of many papers and books. Her most ambitious task was a 700-page psychobiography of Edgar Allan Poe that was first published in French in 1933. She was fascinated by Poe's gothic stories--with the return to life of dead persons and the eerie, unexpected turns of events. Her fascination with Poe can be traced to the similarity of their early traumatic life experiences. Bonaparte had lost her mother a month after her birth. Poe's father deserted the family when Edgar was two years old, and his mother died of tuberculosis when he was three. Poe's stories helped him to accommodate to these early traumatic losses. Bonaparte vicariously shared in Poe's loss and the fantasies of the return of the deceased parent in his stories. She was sensitive and empathetic to Poe's inner world because her inner world was similar. The result of this psychological fit between Poe and Bonaparte was her psychobiography, The Life and Works of Edgar Allan Poe. It was a milestone in psychobiography but limited in its psychological scope by its strong emphasis on early childhood trauma. Nevertheless it proved Bonaparte a bona fide creative psychoanalyst and not a dilettante propped up by her friendship with Freud.

  20. @@%Charcot-Marie-Tooth病一家族分析

    Institute of Scientific and Technical Information of China (English)

    孙明周

    2014-01-01

    目的 通过对1家族Charcot-Marie-Tooth病(cMT)系谱分析,探讨其遗传特点、临床表现及预后,为遗传咨询提供依据.方法 分析家族中患者的性别分布规律,临床表现特点进行分析.结果 家族中男女均可发病,男性患病率明显高于女性.男性患者症状典型,典型症状表现为慢性进展性四肢远端肌肉无力和消瘦肌萎缩呈典型的“鹤腿”,双足骨骼畸形呈“弓形足”;家族中女性患者少见,除Ⅱ8症状表现典型外,其余女性无受累;感觉主诉不显著,无中枢神经受累表现.结论 本例家族CMT呈常染色体显性遗传,男性受累多且症状典型,女性受累少.由于患者症状特征显著,遗传模式明确,预后良好,对于遗传咨询具有指导意义.

  1. The contribution of women to radiobiology: Marie Curie and beyond.

    Science.gov (United States)

    Gasinska, Anna

    2016-01-01

    Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and worked in France, led to the development of nuclear energy and the treatment of cancer. She was the laureate of two Nobel Prizes, the first woman in Europe who obtained the degree of Doctor of Science and opened the way for women to enter fields which had been previously reserved for men only. As a result of her determination and her love of freedom, she has become an icon for many female scientists active in radiation sciences. They are successors of Maria Curie and without the results of their work, improvement in radiation oncology will not be possible. Many of them shared some elements of Maria Curie's biography, like high ethical and moral standards, passionate dedication to work, strong family values, and scientific collaboration with their husbands. The significance of Tikvah Alper, Alma Howard, Shirley Hornsey, Juliana Denekamp, Helen Evans, Eleanor Blakely, Elizabeth L. Travis, Fiona Stewart, Andree Dutreix, Catharine West, Peggy Olive, Ingela Turesson, Penny Jeggo, Irena Szumiel, Eleonor Blakely, Sara Rockwell and Carmel Mothersill contribution to radiation oncology is presented. All the above mentioned ladies made significant contribution to the development of radiotherapy (RT) and more efficient cancer treatment. Due to their studies, new schedules of RT and new types of ionizing radiation have been applied, lowering the incidence of normal tissue toxicity. Their achievements herald a future of personalized medicine.

  2. Charcot-Marie-Tooth disease and other inherited neuropathies.

    Science.gov (United States)

    Saporta, Mario A

    2014-10-01

    Inherited peripheral neuropathies are among the most common genetic neuromuscular disorders worldwide. However, their diagnosis can be challenging due to genotypic and phenotypic variability. Charcot-Marie-Tooth disease (CMT), the most common form, is associated with mutations or copy-number variations in over 70 genes, representing proteins with fundamental roles in the development and function of Schwann cells and peripheral axons. Other genetic peripheral neuropathies are associated with multisystem manifestations, including familial amyloid neuropathy and neuropathies associated with metabolic or other genetic syndromes. This article reviews the most recent discoveries in the field and how they are changing the way neurologists diagnose this specific group of peripheral neuropathies. In the past few years, several large cohort studies on the molecular diagnosis of CMT have been published, providing guidelines for genetic testing in clinical practice. In the same period, next-generation sequencing technology has accelerated the discovery of new CMT genes, expanding our knowledge on genotype-phenotype correlations. Recent advances in sequencing technology and genotype-phenotype correlation studies are changing the way neurologists diagnose inherited neuropathies. New therapeutic strategies for familial amyloid neuropathy are paving the way for innovative treatments for genetic neuropathies.

  3. Trading Places: Mary Shelley’s Argument with Domestic Space

    Directory of Open Access Journals (Sweden)

    Eve M. Lynch

    2013-04-01

    Full Text Available When Mary Shelley began writing The Last Man in 1824 in the wake of her husband Percy Bysshe Shelley’s untimely death, she drew from her close circle of family and friends as models for her main characters. Although it is tempting to view this novel as an autobiographical expiation of the profound sorrow that overwhelmed Shelley at her husband’s death, to do so is to underestimate her prescient political insight and to risk overlooking the complex implications of class and rank that suffuse the position of the narrator, Lionel Verney. While Shelley’s emotions give a passionate appeal to this novel, her intellectual ideas infuse the novel’s powerful critique of British governance. The Last Man is narrated in a political framework in which war and the clash of empires, parliamentary and republican conflict, turbulent revolution, and social and political corruption arrange the fates of the characters. In addition, the plague that silently and invisibly takes over Western Europe and England serves as a spectral process of corrosive malignity from outside, ensnaring all efforts to fix a domestic English system that is collapsing around individuals and the collective.

  4. mitochondrion Spermophilus musicus (Caucasian mountain ground [

    Lifescience Database Archive (English)

    Full Text Available mitochondrion Spermophilus musicus (Caucasian mountain ground [gbrod]: 2 CDS's (760... of codon usage for each CDS (format) Homepage mitochondrion Spermophilus musicus (Caucasian mountain ground ...

  5. Mountains and Tropical Circulation

    Science.gov (United States)

    Naiman, Z.; Goodman, P. J.; Krasting, J. P.; Malyshev, S.; Russell, J. L.; Stouffer, R. J.

    2015-12-01

    Observed tropical convection exhibits zonal asymmetries that strongly influence spatial precipitation patterns. The drivers of changes to this zonally-asymmetric Walker circulation on decadal and longer timescales have been the focus of significant recent research. Here we use two state-of-the-art earth system models to explore the impact of earth's mountains on the Walker circulation. When all land-surface topography is removed, the Walker circulation weakens by 33-59%. There is a ~30% decrease in global, large-scale upward vertical wind velocities in the middle of the troposphere, but only minor changes in global average convective mass flux, precipitation, surface and sea-surface temperatures. The zonally symmetric Hadley circulation is also largely unchanged. Following the spatial pattern of changes to large-scale vertical wind velocities, precipitation becomes less focused over the tropics. The weakening of the Walker circulation, but not the Hadley circulation, is similar to the behavior of climate models during radiative forcing experiments: in our simulations, the weakening is associated with changes in vertical wind velocities, rather than the hydrologic cycle. These results indicate suggest that mountain heights may significantly influence the Walker circulation on geologic time scales, and observed changes in tropical precipitation over millions of years may have been forced by changes in tropical orography.

  6. Protected areas in mountains

    Directory of Open Access Journals (Sweden)

    Hamilton, L. S.

    2006-12-01

    Full Text Available

    The importance of a global Protected Areas Network in sustaining appropriate mountain development is presented in this paper. Present status of the world’s “official” Protected Areas in the UN List, and the proportion that are in mountain areas, and including international designations (World Heritage and Biosphere Reserves. Current and future challenges in the management of these special areas are also commented.



    El autor destaca la importancia de una Red Mundial de Espacios Protegidos para el desarrollo sostenible de las montañas. Comenta luego el estatus actual de las Áreas Protegidas “oficiales” del Mundo en la Lista de las Naciones Unidas y qué proporción de ellas forma parte de las montañas, sin olvidar las figuras internacionales de protección como Patrimonio de la Humanidad y Reservas de Biosfera. Para terminar, se discuten los problemas de gestión actuales y futuros de estas áreas tan especiales

  7. YUCCA MOUNTAIN PROJECT - A BRIEFING --

    Energy Technology Data Exchange (ETDEWEB)

    NA

    2003-08-05

    This report has the following articles: Nuclear waste--a long-term national problem; Spent nuclear fuel; High-level radioactive waste; Radioactivity and the environment; Current storage methods; Disposal options; U.S. policy on nuclear waste; The focus on Yucca Mountain; The purpose and scope of the Yucca Mountain Project; The approach for permanently disposing of waste; The scientific studies at Yucca Mountain; The proposed design for a repository at Yucca Mountain; Natural and engineered barriers would work together to isolate waste; Meticulous science and technology to protect people and the environment; Licensing a repository; Transporting waste to a permanent repository; The Environmental Impact Statement for a repository; Current status of the Yucca Mountain Project; and Further information available on the Internet.

  8. European mountain biodiversity

    Directory of Open Access Journals (Sweden)

    Nagy, Jennifer

    1998-12-01

    Full Text Available This paper, originally prepared as a discussion document for the ESF Exploratory Workshop «Trends in European Mountain Biodiversity - Research Planning Workshop», provides an overview of current mountain biodiversity research in Europe. It discusses (a biogeographical trends, (b the general properties of biodiversity, (c environmental factors and the regulation of biodiversity with respect to ecosystem function, (d the results of research on mountain freshwater ecosystems, and (e climate change and air pollution dominated environmental interactions.- The section on biogeographical trends highlights the importance of altitude and latitude on biodiversity. The implications of the existence of different scales over the different levels of biodiversity and across organism groups are emphasised as an inherent complex property of biodiversity. The discussion on ecosystem function and the regulation of biodiversity covers the role of environmental factors, productivity, perturbation, species migration and dispersal, and species interactions in the maintenance of biodiversity. Regional and long-term temporal patterns are also discussed. A section on the relatively overlooked topic of mountain freshwater ecosystems is presented before the final topic on the implications of recent climate change and air pollution for mountain biodiversity.

    [fr] Ce document a été préparé à l'origine comme une base de discussion pour «ESF Exploratory Workshop» intitulé «Trends in European Mountain Biodiversity - Research Planning Workshop»; il apporte une vue d'ensemble sur les recherches actuelles portant sur la biodiversité des montagnes en Europe. On y discute les (a traits biogéographiques, (b les caractéristiques générales- de la biodiversité, (c les facteurs environnementaux et la régulation de la biodiversité par rapport à la fonction des écosystèmes, (d les résultats des études sur les écosystèmes aquatiques des montagnes et (e les

  9. Geology and genesis of uranium-rare earth deposits at Mary Kathleen, Northwest Queensland

    Energy Technology Data Exchange (ETDEWEB)

    Scott, A.K.; Scott, A.G.

    1985-02-01

    The Mary Kathleen uranium deposit occurs in 1740-1780 M yr-old calc-silicate metasedimentary and meta-igneous rocks of the Corella Formation which have been tightly folded into the Mary Kathleen Syncline. The Corella Formation consists of mafic and felsic tuffaceous calc-silicates, quartzite, and minor marble, conglomerate and basic volcanics. Uranium-rare earth mineralisation is closely associated with certain mafic rocks and occurs within or close to garnet-rich masses. At Mary Kathleen, uraninite grains are enclosed mainly by allanite which is distributed through massive garnet as an irregular honeycomb of interconnected shoots and lenses. The mineralisation occurs along strike from dioritic rocks and conglomerate and lies close to the axis of the Mary Kathleen Syncline and adjacent to a major fault zone. At other localities allanite-uraninite mineralisation is broadly stratiform. The mineralisation is interpreted to occur at or near centres of basic volcanism. Garnet formation and uranium-rare earth concentrations are believed to be caused by the volcanism, and to be contemporaneous with it. The former is seen as alteration of a hot, saturated pile of volcano-sedimentary material and the latter as intermittent hydrothermal exhalations. Deposition, volcanism, garnet formation, uranium and rare-earth mineralisation, granite and gabbro formation, and tectonism are seen as a continuum of interrelated processes which operated throughout the period of formation of the rocks in the Mary Kathleen Syncline.

  10. Geology at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-05-01

    Both advocates and critics disagree on the significance and interpretation of critical geological features which bear on the safety and suitability of Yucca Mountain as a site for the construction of a high-level radioactive waste repository. Critics believe that there is sufficient geological evidence to rule the site unsuitable for further investigation. Some advocates claim that there is insufficient data and that investigations are incomplete, while others claim that the site is free of major obstacles. We have expanded our efforts to include both the critical evaluations of existing geological and geochemical data and the collection of field data and samples for the purpose of preparing scientific papers for submittal to journals. Summaries of the critical reviews are presented in this paper.

  11. Iron Mountain Electromagnetic Results

    Energy Technology Data Exchange (ETDEWEB)

    Gail Heath

    2012-07-01

    Iron Mountain Mine is located seventeen miles northwest of Redding, CA. After the completion of mining in early 1960s, the mine workings have been exposed to environmental elements which have resulted in degradation in water quality in the surrounding water sheds. In 1985, the EPA plugged ore stoops in many of the accessible mine drifts in an attempt to restrict water flow through the mine workings. During this process little data was gathered on the orientation of the stoops and construction of the plugs. During the last 25 years, plugs have begun to deteriorate and allow acidic waters from the upper workings to flow out of the mine. A team from Idaho National Laboratory (INL) performed geophysical surveys on a single mine drift and 3 concrete plugs. The project goal was to evaluate several geophysical methods to determine competence of the concrete plugs and orientation of the stopes.

  12. Glacial effects limiting mountain height.

    Science.gov (United States)

    Egholm, D L; Nielsen, S B; Pedersen, V K; Lesemann, J-E

    2009-08-13

    The height of mountain ranges reflects the balance between tectonic rock uplift, crustal strength and surface denudation. Tectonic deformation and surface denudation are interdependent, however, and feedback mechanisms-in particular, the potential link to climate-are subjects of intense debate. Spatial variations in fluvial denudation rate caused by precipitation gradients are known to provide first-order controls on mountain range width, crustal deformation rates and rock uplift. Moreover, limits to crustal strength are thought to constrain the maximum elevation of large continental plateaus, such as those in Tibet and the central Andes. There are indications that the general height of mountain ranges is also directly influenced by the extent of glaciation through an efficient denudation mechanism known as the glacial buzzsaw. Here we use a global analysis of topography and show that variations in maximum mountain height correlate closely with climate-controlled gradients in snowline altitude for many high mountain ranges across orogenic ages and tectonic styles. With the aid of a numerical model, we further demonstrate how a combination of erosional destruction of topography above the snowline by glacier-sliding and commensurate isostatic landscape uplift caused by erosional unloading can explain observations of maximum mountain height by driving elevations towards an altitude window just below the snowline. The model thereby self-consistently produces the hypsometric signature of the glacial buzzsaw, and suggests that differences in the height of mountain ranges mainly reflect variations in local climate rather than tectonic forces.

  13. Cranial nerve involvement in Charcot-Marie-Tooth Disease.

    Science.gov (United States)

    Das, Nirav; Kandalaft, Savannah; Wu, Xiao; Malhotra, Ajay

    2017-03-01

    Charcot-Marie-Tooth Disease (CMT) is a rare disorder with less than 200,000 cases reported in the US every year, making diagnosis challenging. MR and CT imaging has become more common in the evaluation of CMT to identify areas of disease involvement. A 27-year-old female from Guatemala with a past history of polio initially presented to the emergency room for necrotizing pneumonia. MRI images demonstrated smoothly enlarged, mildly enhancing trigeminal nerves. CT showed bony widening of the skull base foramina. The patient was noted to have atrophy and weakness of her extremities with decreased sensation, distal more than proximal, and pes cavus. An electromyogram demonstrated absent response in the right median, ulnar, peroneal, and tibial motor studies and bilateral radial and right sural sensory studies. MRI of the spine demonstrated smooth, symmetric enlargement and mild enhancement of the distal spinal nerve roots and cauda equine. CMT is a group of disorders with a wide range of clinical presentations and abnormalities. Cranial nerve involvement is infrequently described in CMT 1A. In our case and prior studies, there does not appear to be a correlation between cranial nerve involvement and symptoms. Trigeminal neuralgia has been described in patients in CMT, but is not common and was not seen in our patient despite abnormal trigeminal nerve findings on imaging. Our patient also demonstrated involvement of the facial nerve without facial muscle weakness. Clinical features are key in distinguishing CMT 1A from other forms of HMSN. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Charcot-Marie-Tooth病研究进展

    Institute of Scientific and Technical Information of China (English)

    郭晓强; 王江雁; 时兰春; 王仁杰

    2006-01-01

    Charcot-Marie-Tooth disease(CMT病)是一种进行性神经性肌萎缩综合征,又称遗传性运动和感觉神经性疾病(HMSN)和腓骨肌萎缩症(PMA),CMT病本身并不会危害患者的生命,但却严重影响患者的身体状况,给他们的日常生活带来不便。CMT病的进展比较缓慢,患者的临床表现主要是控制脚/小腿或手,前臂的感觉信息和肌肉萎缩为特征,伴感觉障碍、脊柱及足畸形、植物神经功能紊乱等症状。CMT病是最普遍的遗传性神经疾病之一,至今仍没有有效的治疗方法。但随着研究的深入,人们逐渐对CMT病有了更为全面的认识,在治疗上也开始出现一些新的选择,从而为这种疾病的症状改善和最终的治愈带来了希望。

  15. Contaminant dispersion at the rehabilitated Mary Kathleen uranium mine, Australia

    Science.gov (United States)

    Lottermoser, B. G.; Ashley, P. M.; Costelloe, M. T.

    2005-09-01

    This study reports on the transfer of contaminants from waste rock dumps and mineralised ground into soils, sediments, waters and plants at the rehabilitated Mary Kathleen uranium mine in semi-arid northwest Queensland. Numerous waste rock dumps were partly covered with benign soil and the open pit mine was allowed to flood. The mineralised and waste calc-silicate rock in the open pit and dumps has major (>1 wt%) Ca, Fe and Mg, minor (>1,000 ppm) Ce, La, Mn, P and S, subminor (>100 ppm) Ba, Cu, Th and U, and trace (pit, mobilising many elements and leading to their dispersion into soils, stream sediments, pit water and several plant species. Chemical dispersion is initiated by sulfide mineral breakdown, generation of sulfuric acid and formation of several soluble, transient sulfate minerals as evaporative efflorescent precipitates. Radiation doses associated with the open pit average 5.65 mSv year-1; waste dumps commonly have lower values, especially where soil-covered. Surface pit water is slightly acid, with high sulfate values accompanied by levels of U, Cu and Ni close to or above Australian water guideline values for livestock. Dispersion of U and related elements into soils and stream sediments occurs by physical (erosional) processes and from chemical precipitation. Plants growing in the mine void, on waste dumps and contaminated soil display evidence of biological uptake of U, LREE, Cu and Th and to a lesser degree of As, Ni, Pb, Y and Zn, with values being up to 1-2 orders of magnitude above background sites for the same species. Although rehabilitation procedures have been partly successful in reducing dispersion of U and related elements into the surrounding environment, it is apparent that 20 years after rehabilitation, there is significant physical and chemical mobility, including transfer into plants.

  16. [Mountain medicine - an introduction. I].

    Science.gov (United States)

    Hjuler, Kasper Fjellhaugen; Bay, Bjørn

    2016-10-31

    Tourism to high-altitude areas is increasingly popular even from low-lying regions such as Denmark. Mountain sports include skiing, mountaineering, and ski touring. The young, elderly and at-risk individuals with pre-existing illnesses engage in recreational mountain activities. Thus, risk assessment and counselling regarding altitude exposure is increasingly relevant to all healthcare providers. In this first article of two in a review series, we summarize the state of the art of altitude physiology, alpine dangers and avalanches, and medical aspects of the increased UV-exposure at altitude.

  17. 27 CFR 9.80 - York Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false York Mountain. 9.80... Mountain. (a) Name. The name of the viticultural area described in this section is “York Mountain.” (b) Approved map. The approved map for the York Mountain viticultural area is the U.S.G.S. map entitled...

  18. 27 CFR 9.108 - Ozark Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Ozark Mountain. 9.108... Ozark Mountain. (a) Name. The name of the viticultural area described in this section is “Ozark Mountain.” (b) Approved maps. The appropriate maps for determining the boundaries of Ozark Mountain...

  19. 27 CFR 9.55 - Bell Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Bell Mountain. 9.55... Mountain. (a) Name. The name of the viticultural area described in this section is “Bell Mountain.” (b) Approved map. The appropriate map for determining the boundaries of the Bell Mountain viticultural area...

  20. 27 CFR 9.167 - Red Mountain

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Red Mountain 9.167 Section... Mountain (a) Name. The name of the viticultural area described in this section is “Red Mountain.” (b) Approved maps. The appropriate map for determining the boundaries of the Red Mountain viticultural area...

  1. Using superconducting undulator for enhanced imaging capabilities of MaRIE

    Energy Technology Data Exchange (ETDEWEB)

    Yampolsky, Nikolai [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-22

    MaRIE x-ray free electron laser (FEL) is envisioned to deliver a burst of closely spaced in time pulses for enabling the capability of studying the dynamic processes in a sample. MaRIE capability can be largely enhanced using the superconducting undulator, which has the capability of doubling its period. This technology will allow reaching the photon energy as low as ~200-500 eV. As a result, the MaRIE facility will have a broader photon energy range enabling a larger variety of experiments. The soft x-ray capability is more likely to achieve the 3D imaging of dynamic processes in noncrystal materials than the hard x-ray capability alone.

  2. 7 CFR 14.6 - Criteria for determining the pri- mary purpose of payments with respect to potential exclusion...

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Criteria for determining the pri- mary purpose of payments with respect to potential exclusion from gross income. 14.6 Section 14.6 Agriculture Office of the... Criteria for determining the pri- mary purpose of payments with respect to potential exclusion from...

  3. Rundum artist-run space and its elusive form / Hanna Laura Kaljo, Mari-Leen Kiipli, Kulla Laas ... [jt.

    Index Scriptorium Estoniae

    2015-01-01

    Rundum on 2013. a septembris Tallinnas loodud liikuv loominguline platvorm, mille eesmärgiks on suhestuda erinevate kohtadega, reageerida tühikutele Eesti loomemaastikus ning uurida sealjuures ka omaalgatuslike praktikate võimalikkust kohalikus kontekstis. Vestlusringis Rundumi algatajad Mari-Leen Kiipli, Kulla Laas, Aap Tepper, Mari Volens, Kristina Õllek

  4. ReUse Republic annab mõistele "uuskasutus" uue tähenduse / Tanel Veenre, Mari Klein

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Moe- ja disainiagentuuri KalaMari uuest kaubamärgist ReUse Republic. Tegu on seisma jäänud brändirõivaste ümberdisainimise ja (uus)kasutusega. Projekti looja Mari Martin, kaasatud 15 eesti disainerit

  5. ReUse Republic annab mõistele "uuskasutus" uue tähenduse / Tanel Veenre, Mari Klein

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Moe- ja disainiagentuuri KalaMari uuest kaubamärgist ReUse Republic. Tegu on seisma jäänud brändirõivaste ümberdisainimise ja (uus)kasutusega. Projekti looja Mari Martin, kaasatud 15 eesti disainerit

  6. Sister Mary Joseph Nodules on 99mTc HYNIC-TOC scintigraphy in patients with neuroendocrine tumors.

    Science.gov (United States)

    Jing, Hongli; Zhang, Yingqiang; Li, Fang

    2015-02-01

    A Sister Mary Joseph nodule represents an umbilical metastasis, which is more commonly caused by a primary malignancy in gastrointestinal tract or from reproductive system. We report Sister Mary Joseph nodules caused by neuroendocrine tumor and revealed on Tc HYNIC-TOC scintigraphy.

  7. Rundum artist-run space and its elusive form / Hanna Laura Kaljo, Mari-Leen Kiipli, Kulla Laas ... [jt.

    Index Scriptorium Estoniae

    2015-01-01

    Rundum on 2013. a septembris Tallinnas loodud liikuv loominguline platvorm, mille eesmärgiks on suhestuda erinevate kohtadega, reageerida tühikutele Eesti loomemaastikus ning uurida sealjuures ka omaalgatuslike praktikate võimalikkust kohalikus kontekstis. Vestlusringis Rundumi algatajad Mari-Leen Kiipli, Kulla Laas, Aap Tepper, Mari Volens, Kristina Õllek

  8. Biomechanical effects of sensorimotor orthoses in adults with Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Wegener, Caleb; Wegener, Katrin; Smith, Richard; Schott, Karl-Heinz; Burns, Joshua

    2016-08-01

    Charcot-Marie-Tooth disease is an inherited neuropathy causing progressive weakness, foot deformity and difficulty walking. Clinical anecdotes suggest orthoses designed on the 'sensorimotor' paradigm are beneficial for improving gait in Charcot-Marie-Tooth disease. Investigate the effect of sensorimotor orthoses on in-shoe and lower limb biomechanics in adults with Charcot-Marie-Tooth disease. Randomised, repeated-measures, exploratory study. Eight males and two females with Charcot-Marie-Tooth disease aged 31-68 years fitted with pedorthic shoes and custom-made sensorimotor orthoses were randomly tested at baseline and after 4 weeks of adaptation. In-shoe three-dimensional multi-segment foot and lower limb kinematics and kinetics were collected as were plantar pressures, electromyography and self-reported comfort, stability, cushioning and preference. Compared to the shoe only condition, sensorimotor orthoses increased midfoot eversion and plantarflexion, increased ankle eversion and produced small but significant changes at the knee and hip indicating increased internal rotation. The orthoses increased medial ground reaction forces and increased pressure at the heel, midfoot and toes. There were minimal effects on electromyography. The sensorimotor orthoses were rated higher for comfort, cushioning, stability and preference. Sensorimotor orthoses produced changes in kinematic, kinetic and pressure variables in adults with Charcot-Marie-Tooth disease and were regarded as more comfortable, cushioned and stable during walking. In this study, the walking ability of patients with Charcot-Marie-Tooth disease improved with the use of foot orthoses designed according to the sensorimotor paradigm. However, the mechanism of action appears to be primarily mechanical in origin. Randomised controlled trials are necessary to evaluate the long-term patient-reported outcomes of sensorimotor orthoses. © The International Society for Prosthetics and Orthotics 2015.

  9. The Dilemma of Mountain Roads

    Science.gov (United States)

    Mountain roads and trails are proliferating throughout developing Southeast Asia with severe but largely unrecognized long-term consequences related to effects of landslides and surface erosion on communities and downstream resources.

  10. A mountain of millipedes IV

    DEFF Research Database (Denmark)

    Enghoff, Henrik

    2016-01-01

    Two species of the genus Prionopetalum Attems, 1909, are recorded from the Udzungwa Mountains: P. asperginis sp. nov. and P. kraepelini (Attems, 1896). Prionopetalum stuhlmanni Attems, 1914, is synonymized under P. kraepelini. Odontopyge fasciata Attems, 1896, is transferred from Prionopetalum...

  11. The Table Mountain Field Site

    Data.gov (United States)

    Federal Laboratory Consortium — The Table Mountain Field Site, located north of Boulder, Colorado, is designated as an area where the magnitude of strong, external signals is restricted (by State...

  12. Cx32 gene mutation associated with X-linked recessive Charcot-Marie-Tooth disease

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The form of Charcot-Marie-Tooth (CMT) neuropathy that maps to Xq13 is X-linked dominant, or X-linked intermediate. Heterozygous females are more mildly affected than hemizygous males. It has been known that this type of CMT is caused by mutations of connexin32 (Cx32) gene. A typical X-linked recessive Charcot-Marie-Tooth Chinese family was analyzed with single strand conformation polymorphism method. A Cx32 gene point mutation, Arg15Gln, in exon 2 was identified in all affected family members, suggesting that this mutation is responsible for the CMT incidence of this family.

  13. 1970. aastatel alustas arhitektidest sõprade ja kolleegide rühm... / Mari Laanemets

    Index Scriptorium Estoniae

    Laanemets, Mari, 1975-

    2008-01-01

    27.VI avatakse Eesti Arhitektuurimuuseumis Rotermanni soolalaos 1970. ja 1980. alguse eksperimentaalset arhitektuuripraktikat käsitlev näitus "Keskkond, objektid, kontseptsioonid. Tallinna kooli arhitektid 1972-1985". Näha saab Ülevi Eljandi, Ignar Fjuki, Veljo Kaasiku, Tiit Kaljundi, Vilen Künnapu, Leonhard Lapini, Avo-Himm Looveere, Kristin-Mari Looveere, Marika Lõokese, Jüri Okase, Jaan Olliku, Ain Padriku, Toomas Reinu, Andres Ringo, Sirje Runge, Harry Sheini, Tõnis Vindi ja Matti Õunapuu töid. Näituse kuraatorid Andres Kurg ja Mari Laanemets. Samas: "Uue arhitektuuri näituse programm" (1972)

  14. M-ary suprathreshold stochastic resonance in multilevel threshold systems with signal-dependent noise

    Science.gov (United States)

    Cheng, Chaojun; Zhou, Bingchang; Gao, Xiao; McDonnell, Mark D.

    2017-08-01

    We investigate multilevel threshold systems with signal-dependent noise that transmit a common random input signal. We demonstrate the occurrence of M-ary suprathreshold stochastic resonance caused by the signal-dependent noise, and quantify the information enhancement that results relative to the absence of noise. We also find that in the case of M-ary threshold systems, the values of mutual information and signal-to-quantization-noise ratio are larger than the corresponding values in the case of binary threshold systems. These results are potentially useful for understanding the encoding mechanism of inner-ear hair cells and other biological sensory systems.

  15. Althusser en Haïti. De Port-au-Prince au polder Marie-Anne

    Directory of Open Access Journals (Sweden)

    Marie-Anne Paveau

    2012-11-01

    Full Text Available Cette contribution formule un témoignage personnel de Marie-Anne Paveau. L'auteure est intervenue à Port-au-Prince en 2006 auprès des étudiants de la Faculté de Linguistique appliquée, alors administrée par Pierre Vernet. Marie-Anne Paveau y présente notamment les éléments du cours qu'elle y a dispensé, illustrant de ce fait la collaboration conduite de 2005 à 2009 entre la Faculté et plusieurs universités de l'étranger.

  16. Marie Unna遗传性少毛症一家系7例

    Institute of Scientific and Technical Information of China (English)

    邵娟; 张立; 赵天恩

    2009-01-01

    遗传性少毛症(hereditary hypotrichosis)即先天性脱发症(congenital alopecia),临床罕见,有常染色体显性、隐性和性连锁三种遗传方式,Marie Unna遗传性少毛症(Marie Unna hereditary hypotrichosis,MUHH)属常染色体显性遗传,现将我们所见一家系报道如下。

  17. The Education of a Monster. A Feminist Reading of Mary Shelley's Frankenstein

    OpenAIRE

    2010-01-01

    This B.A. Essay examines feminism in Mary Shelley’s Frankenstein (1818) in relation to such literary works as A Vindication of the Rights of Woman (1792) by Mary Wollstonecraft and Paradise Lost (1667) by John Milton. The notion of feminism within the novel and the female identity of such characters as the monster, Elizabeth Lavenza, Justine Moritz and Safie De Lacey are explored. Furthermore the education of the monster, how he learns on his own, is linked with the lack of education for wom...

  18. 1970. aastatel alustas arhitektidest sõprade ja kolleegide rühm... / Mari Laanemets

    Index Scriptorium Estoniae

    Laanemets, Mari, 1975-

    2008-01-01

    27.VI avatakse Eesti Arhitektuurimuuseumis Rotermanni soolalaos 1970. ja 1980. alguse eksperimentaalset arhitektuuripraktikat käsitlev näitus "Keskkond, objektid, kontseptsioonid. Tallinna kooli arhitektid 1972-1985". Näha saab Ülevi Eljandi, Ignar Fjuki, Veljo Kaasiku, Tiit Kaljundi, Vilen Künnapu, Leonhard Lapini, Avo-Himm Looveere, Kristin-Mari Looveere, Marika Lõokese, Jüri Okase, Jaan Olliku, Ain Padriku, Toomas Reinu, Andres Ringo, Sirje Runge, Harry Sheini, Tõnis Vindi ja Matti Õunapuu töid. Näituse kuraatorid Andres Kurg ja Mari Laanemets. Samas: "Uue arhitektuuri näituse programm" (1972)

  19. THE MOST SUCCE SSFUL MOUNTAINEERS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Tsering Dorje:I Dream of Climbing Mt. Qomolangma Carrying the Olympic Torch Tsering Dorje,the oldest of the Tibetan professional mountaineers,has successfully reached a total of fourteen of the world's highest mountain summits.His companions jokingly refer to him as"Aku"(meaning"uncle"in Tibetan).However, acting as an uncle,he has to shoulder the responsibilities of team leader to take care of the others.

  20. Mountain Child: Systematic Literature Review.

    Science.gov (United States)

    Audsley, Annie; Wallace, Rebecca M M; Price, Martin F

    2016-12-01

    Objectives This systematic review identifies and reviews both peer-reviewed and 'grey' literature, across a range of disciplines and from diverse sources, relating to the condition of children living in mountain communities in low- and middle-income countries. Findings The literature on poverty in these communities does not generally focus on the particular vulnerabilities of children or the impact of intersecting vulnerabilities on the most marginalised members of communities. However, this literature does contribute analyses of the broader context and variety of factors impacting on human development in mountainous areas. The literature on other areas of children's lives-health, nutrition, child mortality, education, and child labour-focuses more specifically on children's particular vulnerabilities or experiences. However, it sometimes lacks the broader analysis of the many interrelated characteristics of a mountainous environment which impact on children's situations. Themes Nevertheless, certain themes recur across many disciplines and types of literature, and point to some general conclusions: mountain poverty is influenced by the very local specificities of the physical environment; mountain communities are often politically and economically marginalised, particularly for the most vulnerable within these communities, including children; and mountain communities themselves are an important locus for challenging and interrupting cycles of increasing inequality and disadvantage. While this broad-scale review represents a modest first step, its findings provide the basis for further investigation.

  1. A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients

    Science.gov (United States)

    Guedj, Mickaël; Bertrand, Viviane; Foucquier, Julie; Jouve, Elisabeth; Commenges, Daniel; Proust-Lima, Cécile; Murphy, Niall P.; Blin, Olivier; Magy, Laurent; Cohen, Daniel; Attarian, Shahram

    2017-01-01

    The Charcot-Marie-Tooth Neuropathy Score (CMTNS) was developed as a main efficacy endpoint for application in clinical trials of Charcot-Marie-Tooth disease type 1A (CMT1A). However, the sensitivity of the CMTNS for measuring disease severity and progression in CMT1A patients has been questioned. Here, we applied a Rasch analysis in a French cohort of patients to evaluate the psychometrical properties of the CMTNS. Overall, our analysis supports the validity of the CMTNS for application to CMT1A patients though with some limitations such as certain items of the CMTNS being more suitable for moderate to severe forms of the disease, and some items being disordered. We suggest that additional items and/or categories be considered to better assess mild-to-moderate patients. PMID:28095456

  2. 'BRS Mari': nova cultivar de pimenta dedo-de-moça para processamento 'BRS Mari': new hot pepper cultivar for processing

    Directory of Open Access Journals (Sweden)

    Sabrina Isabel C de Carvalho

    2009-12-01

    Full Text Available 'BRS Mari' é uma nova cultivar de pimenta dedo-de-moça desenvolvida para uso múltiplo, como produto in natura, processada na forma de molho líquido ou desidratada em flocos, moída junto com as sementes, para a produção de pimenta tipo 'calabresa'. A cv. 'BRS Mari' foi desenvolvida a partir da população 'CNPH 0039' por meio de seis ciclos de seleção massal com autofecundação controlada. A nova cultivar apresenta plantas de polinização aberta com hábito de crescimento intermediário, com aproximadamente 90 cm de altura e 1,25 m de largura, com resistência múltipla a doenças, com destaque para o virus Pepper Yellow Mosaic Virus (PepYMV e nematóide das galhas (Meloidogyne javanica, resistência mediana ao oídio (Oidium sicula, mancha bacteriana (Xanthomonas spp. e antracnose (Colletotrichum spp.. A colheita dos frutos tem início cerca de 70 dias após o transplante. Nas condições da região Centro-Oeste, 'BRS Mari' apresentou boa uniformidade de planta, ótima qualidade de fruto e grande potencial produtivo, alcançando 35 t ha-1 em seis meses, quando cultivada no espaçamento de 1 m entre plantas e 1,5 m entre linhas. Os frutos são alongados e pendentes, típicos do tipo dedo-de-moça, com passagem de coloração verde claro, amarelo com antocianina e laranja quando imaturos e vermelho intenso quando maduros, com aproximadamente 6,0 cm de comprimento, 1,4 cm de largura e cerca de 1,7 mm de espessura da parede. A principal característica da 'BRS Mari' é o elevado teor de capsaicina, aproximadamente 90.000 SHU (Unidades de Calor Scoville, mais elevado quando comparada com outras cultivares do mesmo grupo.'BRS Mari' is a new hot pepper cultivar suitable for processing as sauce or dehydrated flakes, ordinarily known in Brazil as 'calabresa' type, as well as for fresh market. Hot pepper cv. 'BRS Mari' was obtained from population 'CNPH 0039', through six cycles of mass selection with controlled selfing of selected plants. The

  3. Visual Double Stars - St. Mary's High School Astronomy Club

    Science.gov (United States)

    Bensel, Holly; Tran, Thanh; Hicks, Sean; He, Yifan; Moczygemba, Mitchell; Shi, Yuqi; Sternenberg, Leah; Watson, Kaycia; Rooney, Kieran; Birmingham, Paige; You, Ruiyang

    2017-01-01

    The St. Mary’s School Astronomy Club is working towards measuring positions and angles of relatively unstudied visual binary stars. We are starting with confirming prior results we obtained at the Pine Mountain Observatory Summer Science Research Workshop in 2009 - 2012 on ARY 52 (Frey et al. 2009, JDSO), Iota Bootis (Bensel et al. 2009, JDSO), and Mizar (Bensel et al. 2009, JDSO). We are also comparing our results with those published in the Washington Double Star Catalog (Mason 2009). We are using Pine Mountain Observatory’s remote imaging 14-inch Meade Schmidt-Cassegrain telescope equipped with a CCD camera operated by Scott Fisher at the University of Oregon and local astronomer Sean Curry’s 12.5" PlaneWave CDK telescope. We are practicing using tools such as astrometry.net and DS9 software to measure positions and angles on known double stars with well established values before attempting new measurements. Our next project will be to study “neglected visual double stars,” lesser studied double stars with fainter magnitudes. (A neglected double star is one that has not been observed extensively or recently.)Double star analysis is relatively straight forward and can be performed with equipment available to most high schools.Educational outcomes include instrument setup, orientation, instruction, observations, analysis, presentation of data, and writing up findings for publication. Accurate recording of data is a useful and important life skill for all students to learn. Another important life skill is learning to work together to accomplish a specific goal. This project allows novice and experienced observers to work hand-in-hand to accomplish a specific goal, such as the publishing of a research paper in the Journal of Double Star Observations.

  4. The origins of mountain geoecology

    Directory of Open Access Journals (Sweden)

    Ives, Jack D.

    2012-05-01

    Full Text Available Mountain geoecology, as a sub-discipline of Geography, stems from the life and work of Carl Troll who, in turn, was inspired by the philosophy and mountain travels of Alexander von Humboldt. As founding chair of the IGU Commission on High-Altitude Geoecology (1968, Troll laid the foundations for inter-disciplinary and international mountain research. The paper traces the evolution of the Commission and its close links with the UNESCO Man and Biosphere Programme (1972- and the United Nations University’s mountain Project (1978-. This facilitated the formation of a major force for inclusion of a mountain chapter in AGENDA 21 during the 1992 Rio de Janeiro Herat Summit (UNCED and the related designation by the United Nations of 2002 as the International Year of Mountains. In this way, mountain geoecology not only contributed to worldwide mountain research but also entered the political arena in the struggle for sustainable mountain development and the well-being of mountain people.La geoecología de montaña, como sub-disciplina de la Geografía, entronca con la vida y trabajo de Carl Troll, quien, a su vez, fue inspirado por la filosofía y viajes de Alexander von Humboldt. Como presidente fundador de la comisión de la UGI sobre High Altitude Geoecology (1968, Troll colocó las bases para la investigación interdisciplinar e internacional de las montañas. Este trabajo presenta la evolución de la Comisión y sus estrechas relaciones con el Programa Hombre y Biosfera de UNESCO (1972- y con el Proyecto de montaña de la Universidad de Naciones Unidas (1978-. Esto facilitó la inclusión de un capítulo sobre la montaña en AGENDA 21 durante la Cumbre de la Tierra de Río de Janeiro (UNCED, y la consiguiente designación de 2002 como el Año Internacional de las Montañas por parte de Naciones Unidas. En este sentido, la geoecología de montaña no sólo contribuyó a la investigación de las montañas del mundo sino que también empujó a la pol

  5. Manifest Destiny's Child: Mary Hazelton Blanchard Wade and the Literature of American Empire

    Science.gov (United States)

    Tunc, Tanfer Emin

    2017-01-01

    This article discusses how, following in the footsteps of United States imperial children's writers Jacob Abbott and Edward Stratemeyer, Mary Hazelton Blanchard Wade (1860-1936), the original author of the "Our Little Cousins" series (1901-1905), contributed to the American culture of empire. Wade was one of the most prolific and popular…

  6. Hand involvement in children with Charcot-Marie-Tooth disease type 1A

    NARCIS (Netherlands)

    Burns, Joshua; Bray, Paula; Cross, Lauren A.; North, Kathryn N.; Ryan, Monique M.; Ouvrier, Robert A.

    2008-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A), a demyelinating neuropathy characterised by progressive length-dependent muscle weakness and atrophy, is thought to affect the foot and leg first followed some time later by hand weakness and dysfunction. We aimed to characterise hand Strength, function a

  7. Women's Emancipation through Education: The Radical Agenda of Mary Wollstonecraft (1759-1797).

    Science.gov (United States)

    Roberts, Leonard H.; Pollman, Mary Jo

    Two hundred years ago, Mary Wollstonecraft, the English women's rights pioneer, published her immortal work: "A Vindication of the Rights of Woman." In it she placed much of the blame for women's inferior political, intellectual, and social status on "faulty education." In "Vindication," she offered a number of…

  8. Kunsti kuumtöötlus Läti aladel / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Pedvale vabaõhumuuseumis toimunud rahvusvahelisest workshop'ist teemal "Kompost", mille tulemusi presenteeriti 6. VIII 2004. Ignas Kazakeviciuse, Jurate Rakeviciute, Diana Dimzha-Dime, Ule Björn Gundermanni, Remo Randveri, Maris Grosbahsi, Andrus Joonase töödest

  9. Strangers and Orphans: Knowledge and Mutuality in Mary Shelley's "Frankenstein"

    Science.gov (United States)

    Gomez, Claudia Rozas

    2013-01-01

    Paulo Freire consistently upheld humanization and mutuality as educational ideals. This article argues that conceptualizations of knowledge and how knowledge is sought and produced play a role in fostering humanization and mutuality in educational contexts. Drawing on Mary Shelley's novel "Frankenstein," this article focuses on the…

  10. Difficulties in teaching electromagnetism: an eight year experience at Pierre and Marie Curie University

    Directory of Open Access Journals (Sweden)

    H. Roussel

    2012-07-01

    Full Text Available We will begin by outlining the details of how electromagnetics are taught in the  electrical engineering program offered at Pierre and Marie Curie University (a French example from the undergraduate to the Masters degree levels.  We will also discuss how our methods are and should be adapted to teach waves propagation without discouraging students.

  11. Breaking the Boundaries of Victorian Imperialism or Extending a Reformed 'Paternalism'? Mary Carpenter and India.

    Science.gov (United States)

    Watts, Ruth

    2000-01-01

    Discusses the debate on gender and imperialism in India by examining the case of Mary Carpenter, a nineteenth century English educationist and social reformer, in order to provide more information on the debate. Addresses where Carpenter stood in the discourse on imperialism. (CMK)

  12. Uus nobelist : prantslane Jean-Marie Gustave Le Clézio / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2008-01-01

    Nobeli kirjandusauhind 2008 - prantsuse romaanikirjanik Jean-Marie Gustave Le Clézio. Sisaldab autori eesti keelde tõlgitud teoste annotatsioone: Päev, mil Beaumont tegi tutvust oma valuga : [novell] / tlk. Merike Riives (kogumikust Prantsuse novell, 1973); Kõrb / tlk. Kristiina Ross (Eesti Raamat, 1990); Diego ja Frida / tlk. Sirje Keevallik (Kunst, 2007)

  13. Mis me teeme Shakespeareìga? / Maris Pähn

    Index Scriptorium Estoniae

    Pähn, Maris

    2002-01-01

    Tallinnas Eesti Akadeemilises Raamatukogus on avatud näitus Shakespeare℗ѫi elu ja loomingut käsitlevast eestikeelsest kirjavarast. Näituse pani kokku Eesti Humanitaarinstituudi magistrant Maris Pähn. Ülevaade näitusel eksponeeritavast materjalist

  14. Novels, Thought Experiments, and Humanist Sociology in the Classroom: Mari Sandoz and CAPITAL CITY.

    Science.gov (United States)

    Hill, Michael R.

    1987-01-01

    Based upon the teaching of Mari Sandoz' allegorical novel, CAPITAL CITY, this article identifies the characteristics of novels which provide a sociologically useful humanist perspective. A key characteristic is the extent to which the novel conducts thought experiments, defined as cerebral exercises which explore alternative social futures based…

  15. The Marie Curie Actions at CERN – reaching out beyond particle physics and Europe

    CERN Multimedia

    EU Projects Office

    2014-01-01

    The European Commission’s Marie Curie Actions have been a pillar of the EU Framework Programmes for several decades as a means of promoting career development and enhancing mobility of researchers in Europe. This corresponds nicely to one of CERN’s main missions: to train the next generation of scientists and engineers.   The European Commissioner for Education, Culture, Multilingualism, Sport, Media and Youth, Androulla Vassiliou (centre) met the Marie Curie Fellows on her visit to CERN in April 2013. CERN has been pleased to be a major player in the Marie Curie Actions under the Sixth and Seventh Framework Programmes (FP6 from 2002 to 2006 and FP7 from 2007 to 2013), being one of the most successful participants in Europe. Under FP7, CERN was ranked first in Switzerland and fifth in Europe against stiff competition in terms of overall funding. Participation was in all of the Marie Curie Actions: Initial Training Networks, Industry-Academia Partnership Pathways, IRSES, CO...

  16. Mari sangari päeva sõnum / Jaak Prozes ; interv. Livia Viitol

    Index Scriptorium Estoniae

    Prozes, Jaak, 1965-

    2006-01-01

    Fenno-Ugria Hõimukeskuse juhataja ja Eestimaa Rahvaste Ühenduse juht soome-ugri rahvaste olukorrast Venemaal ja rahvusseltside tegevusest Eestis. Aprilli lõpul tähistasid marid oma rahvuspüha - mari sangari päeva. Pärimuse põhjal langes maride rahvuskangelane Boltu̧ võitluses oma rahva vabaduse eest 26. aprillil 1556

  17. Nerve Excitability Properties in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Nodera, Hiroyuki; Bostock, Hugh; Kuwabara, Satoshi; Sakamoto, Takashi; Asanuma, Kotaro; Jia-Ying, Sung; Ogawara, Kazue; Hattori, Naoki; Hirayama, Masaaki; Kaji, Ryuji

    2004-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) is commonly considered a prototype of a hereditary demyelinating polyneuropathy. Apart from the myelin involvement, there has been little information on axonal membrane properties in this condition. Taking advantage of the uniform nature of the disease process, we undertook the "in vivo" assessment of…

  18. Connexin32 gene mutations in X-linked dominant Charcot-Marie-Tooth disease (CMTX1)

    NARCIS (Netherlands)

    Janssen, EAM; Kemp, S; Hensels, GW; Sie, OG; deDieSmulders, CEM; Hoogendijk, JE; deVisser, M; Bolhuis, PA

    Single-strand conformational polymorphisms (SSCP) of the connexin32 gene were analyzed in 121 patients possibly affected by Charcot-Marie-Tooth (CMT) disease. The 121 patients were selected from 443 possible CMT/HNPP (hereditary neuropathy with liability to pressure palsies) patients based on

  19. A LRSAM1 mutation links Charcot-Marie-Tooth type 2 to Parkinson's disease

    NARCIS (Netherlands)

    Aerts, M.B.; Weterman, M.A.; Quadri, M.; Schelhaas, H.J.; Bloem, B.R.; Esselink, R.A.; Baas, F.; Bonifati, V.; Warrenburg, B.P. van de

    2016-01-01

    LRSAM1 mutations have been found in recessive and dominant forms of Charcot-Marie-Tooth disease. Within one generation of the original Dutch family in which the dominant LRSAM1 mutation was identified, three of the five affected family members have developed Parkinson's disease between ages 50 and

  20. St Thomas' hospital is the wrong site for mary seacole statue.

    Science.gov (United States)

    McDonald, Lynn

    2012-05-16

    Your news story, 'Council gives go-ahead for Seacole statue' (May 2), is orrect in declaring that planning permission for a memorial statue for Mary Seacole has been granted. But the plans have been approved by Lambeth Council's planning committee, rather than the council as a whole.

  1. Re-Birthing the Monstrous: James Whale's (Mis)Reading of Mary Shelley's "Frankenstein."

    Science.gov (United States)

    Picart, Caroline Joan S.

    1998-01-01

    Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine divinity and…

  2. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  3. Mari sangari päeva sõnum / Jaak Prozes ; interv. Livia Viitol

    Index Scriptorium Estoniae

    Prozes, Jaak, 1965-

    2006-01-01

    Fenno-Ugria Hõimukeskuse juhataja ja Eestimaa Rahvaste Ühenduse juht soome-ugri rahvaste olukorrast Venemaal ja rahvusseltside tegevusest Eestis. Aprilli lõpul tähistasid marid oma rahvuspüha - mari sangari päeva. Pärimuse põhjal langes maride rahvuskangelane Boltu̧ võitluses oma rahva vabaduse eest 26. aprillil 1556

  4. Mary Lincoln's Madness: Understanding the Factors that Influence the Diagnosis and Treatment of Bipolar Disorder

    Science.gov (United States)

    Dick, Carina; Renes, Susan L.; Strange, Anthony T.

    2010-01-01

    Mary Lincoln, wife of President Abraham Lincoln, lived a tragic life. Beginning with the death of her mother when she was a little girl, Mrs. Lincoln experienced a number of family deaths, including three brothers, three sons, and the murder of her beloved husband while she sat by his side. In addition to tragedy, Mrs. Lincoln suffered from poor…

  5. Dr. Mary McLeod Bethune: A Life Devoted to Service

    Science.gov (United States)

    Long, Kim Cliett

    2011-01-01

    The purpose of this paper is to explore and analyze the leadership traits of Dr. Mary McLeod Bethune, an African-American woman of history, using the servant leadership theory developed by Robert K. Greenberg and the ten characteristics of servant leadership as conceived by Larry C. Spears. This exploration seeks to identify the significant…

  6. Projektilugu: Viipekeele tõlkide õppekava Tartu Ülikoolis / Mari Reilson

    Index Scriptorium Estoniae

    Reilson, Mari

    2014-01-01

    Ülikoolide ja ettevõtete koostöö alameetme projektist "Õppekava eesti viipekeele tõlk arendamine, juurutamine ning jätkusuutlikkuse tagamine!". Küsimustele vastab Tartu Ülikooli Eesti viipekeeletõlkide õppekava programmijuht Mari Reilson

  7. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  8. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    OpenAIRE

    Jan Whitaker

    2017-01-01

    In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  9. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    Directory of Open Access Journals (Sweden)

    Jan Whitaker

    2017-02-01

    Full Text Available In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  10. Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing.

    LENUS (Irish Health Repository)

    Murphy, Sinead M

    2012-07-01

    Charcot-Marie-Tooth disease (CMT) is a clinically and genetically heterogeneous group of diseases with approximately 45 different causative genes described. The aims of this study were to determine the frequency of different genes in a large cohort of patients with CMT and devise guidelines for genetic testing in practice.

  11. Nerve Excitability Properties in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Nodera, Hiroyuki; Bostock, Hugh; Kuwabara, Satoshi; Sakamoto, Takashi; Asanuma, Kotaro; Jia-Ying, Sung; Ogawara, Kazue; Hattori, Naoki; Hirayama, Masaaki; Kaji, Ryuji

    2004-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) is commonly considered a prototype of a hereditary demyelinating polyneuropathy. Apart from the myelin involvement, there has been little information on axonal membrane properties in this condition. Taking advantage of the uniform nature of the disease process, we undertook the "in vivo" assessment of…

  12. Neuromuscular Hip Dysplasia in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Bamford, Nigel S.; White, Klane K.; Robinett, Stephanie A.; Otto, Randolph K.; Gospe, Sidney M., Jr.

    2009-01-01

    Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting 36 in 100,000 people. CMT type 1A (hereditary motor and sensory neuropathy) is the most frequent form of this disease, affecting 60 to 80% of the CMT population, but its diagnosis may be delayed because of inconsistent clinical signs and…

  13. Effective cauda equina decompression in two siblings with Charcot-Marie-Tooth disease type 1B

    NARCIS (Netherlands)

    van Doormaal, Tristan P C; van Ruissen, Fred; Miller, Kai J; Hoogendijk, Jessica E

    2016-01-01

    Two siblings with Charcot-Marie-Tooth (CMT) 1B due to a c.517G>C (p.Gly173Arg) mutation in the MPZ gene both developed an acute cauda syndrome with unbearable back pain radiating to both legs, progressive muscle weakness of the legs, and saddle hypesthesia with fecal and urinary incontinence. MRI sh

  14. Living Proof: What Helen Keller, Marilyn Monroe, and Marie Curie Have in Common.

    Science.gov (United States)

    Saul, E. Wendy

    1986-01-01

    Examines biographies of Marie Curie written for children and discusses two types of distortions: simple misrepresentations of fact and selective retelling of the past. It is concluded that biographies of minority or female success should deal specifically with strategies used by the hero or heroine to combat prejudice. (EM)

  15. Effective cauda equina decompression in two siblings with Charcot-Marie-Tooth disease type 1B

    NARCIS (Netherlands)

    van Doormaal, Tristan P C; van Ruissen, Fred; Miller, Kai J; Hoogendijk, Jessica E

    2016-01-01

    Two siblings with Charcot-Marie-Tooth (CMT) 1B due to a c.517G>C (p.Gly173Arg) mutation in the MPZ gene both developed an acute cauda syndrome with unbearable back pain radiating to both legs, progressive muscle weakness of the legs, and saddle hypesthesia with fecal and urinary incontinence. MRI

  16. From Cradleboard to Motherboard: Buffy Sainte-Marie's Interactive Multimedia Curriculum Transforms Native American Studies.

    Science.gov (United States)

    King, Claire

    2000-01-01

    Describes "Science: Through Native American Eyes," an interactive multimedia CD-ROM for middle school that is part of the Cradleboard Teaching Project developed by musician and teacher Buffy Sainte-Marie. The Cradleboard joins Native American tradition and high-tech innovation to explore the core curriculum of the National Content Standards. (SLD)

  17. Kunsti kuumtöötlus Läti aladel / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Pedvale vabaõhumuuseumis toimunud rahvusvahelisest workshop'ist teemal "Kompost", mille tulemusi presenteeriti 6. VIII 2004. Ignas Kazakeviciuse, Jurate Rakeviciute, Diana Dimzha-Dime, Ule Björn Gundermanni, Remo Randveri, Maris Grosbahsi, Andrus Joonase töödest

  18. Unheralded Historian: Mary Sheldon Barnes and Primary Source Material in History Books

    Science.gov (United States)

    Chisholm, James A., Jr.

    2013-01-01

    In the latter part of the nineteenth century, Mary Sheldon Barnes emerged as a leading historical methods professor and history textbook author. Although men dominated the field, she wrote several articles and books alone or with her husband Earl Barnes about primary source materials and teaching. She lived during an era in United States history…

  19. Re-Birthing the Monstrous: James Whale's (Mis)Reading of Mary Shelley's "Frankenstein."

    Science.gov (United States)

    Picart, Caroline Joan S.

    1998-01-01

    Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine…

  20. Walt Disney Meets Mary Daly: Invention, Imagination, and the Construction of Community.

    Science.gov (United States)

    Covino, William A.

    2000-01-01

    Posits Walt Disney as an influential sorcerer in the process of integrating the real world into Disney's synthetic universe, and Mary Daly's work "Wickedary" as a work that constructs an alternative "magic kingdom" through an insistence on an anti-patriarchal lexicon. (NH)

  1. Connexin32 gene mutations in X-linked dominant Charcot-Marie-Tooth disease (CMTX1)

    NARCIS (Netherlands)

    Janssen, EAM; Kemp, S; Hensels, GW; Sie, OG; deDieSmulders, CEM; Hoogendijk, JE; deVisser, M; Bolhuis, PA

    1997-01-01

    Single-strand conformational polymorphisms (SSCP) of the connexin32 gene were analyzed in 121 patients possibly affected by Charcot-Marie-Tooth (CMT) disease. The 121 patients were selected from 443 possible CMT/HNPP (hereditary neuropathy with liability to pressure palsies) patients based on geneti

  2. From Cradleboard to Motherboard: Buffy Sainte-Marie's Interactive Multimedia Curriculum Transforms Native American Studies.

    Science.gov (United States)

    King, Claire

    2000-01-01

    Describes "Science: Through Native American Eyes," an interactive multimedia CD-ROM for middle school that is part of the Cradleboard Teaching Project developed by musician and teacher Buffy Sainte-Marie. The Cradleboard joins Native American tradition and high-tech innovation to explore the core curriculum of the National Content Standards. (SLD)

  3. Mary Munford Model School and Virginia Commonwealth University: Unexpected Benefits in a Working Partnership.

    Science.gov (United States)

    Fox, Jill Englebright; Branch, Stacey B.

    1999-01-01

    Describes the 5-year-old Professional Development School (PDS) relationship between the Mary Munford Model School near Richmond, Virginia, and Virginia Commonwealth University. The PDS focuses on goals of the Holmes Partnership. This paper looks at the stories of a classroom teacher and a university educator involved in the PDS. (SM)

  4. Marie Underi ühe luuletuse ümber / August Eelmäe

    Index Scriptorium Estoniae

    Eelmäe, August, 1931-

    2003-01-01

    Marie Underi luuletusest "Me ootame" ja selle vaheredaktsioonist, avaldatud pealkirjaga "Üks päev" (Oma Maa, 1947, nr. 2). Ilmunud ka kogumikus: Eelmäe, August. Kõned ja kirjatööd. Tallinn : Underi ja Tuglase Kirjanduskeskus, 2006, lk. 56-71

  5. Re-Birthing the Monstrous: James Whale's (Mis)Reading of Mary Shelley's "Frankenstein."

    Science.gov (United States)

    Picart, Caroline Joan S.

    1998-01-01

    Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine…

  6. Strangers and Orphans: Knowledge and Mutuality in Mary Shelley's "Frankenstein"

    Science.gov (United States)

    Gomez, Claudia Rozas

    2013-01-01

    Paulo Freire consistently upheld humanization and mutuality as educational ideals. This article argues that conceptualizations of knowledge and how knowledge is sought and produced play a role in fostering humanization and mutuality in educational contexts. Drawing on Mary Shelley's novel "Frankenstein," this article focuses on the…

  7. Connexin32 gene mutations in X-linked dominant Charcot-Marie-Tooth disease (CMTX1)

    NARCIS (Netherlands)

    Janssen, EAM; Kemp, S; Hensels, GW; Sie, OG; deDieSmulders, CEM; Hoogendijk, JE; deVisser, M; Bolhuis, PA

    1997-01-01

    Single-strand conformational polymorphisms (SSCP) of the connexin32 gene were analyzed in 121 patients possibly affected by Charcot-Marie-Tooth (CMT) disease. The 121 patients were selected from 443 possible CMT/HNPP (hereditary neuropathy with liability to pressure palsies) patients based on geneti

  8. Muuga / Mary von Grünewaldt ; tõlk. Mati Sirkel

    Index Scriptorium Estoniae

    Grünewaldt, Mary von

    2004-01-01

    Leo Zoegelt ostetud Muuga mõisahoone korrastamisest ja uue hoone ehitamisest C. T. von Neffi kunstikogu paigutamise tarbeks. Tütre mälestused. Tõlgitud raamatust: Skizzen und Bilder aus dem Leben Carl Timoleon von Neff / Mary von Grünewaldt. Darmstadt, 1887

  9. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Science.gov (United States)

    2010-04-28

    ... Surface Transportation Board Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St... from STMA's parent, Potlatch Land & Lumber, LLC, by Williams Group, Inc. (WG).\\2\\ Applicant...

  10. Neuromuscular Hip Dysplasia in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Bamford, Nigel S.; White, Klane K.; Robinett, Stephanie A.; Otto, Randolph K.; Gospe, Sidney M., Jr.

    2009-01-01

    Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting 36 in 100,000 people. CMT type 1A (hereditary motor and sensory neuropathy) is the most frequent form of this disease, affecting 60 to 80% of the CMT population, but its diagnosis may be delayed because of inconsistent clinical signs and…

  11. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  12. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  13. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri

    2003-01-01

    Concordia Ülikooli rektori kohast loobunud Mart Susi ning prorektori ametikohalt lahkunud Mari-Ann Susi taotlevad neile kuuluvat ülikooli pidanud miljonivõlgades firma pankrotti. Hiljuti loodi õppejõududest, tudengitest js töötajatest mittetulundusühing Concordia Akadeemiline Ühisus (CAU), selle nõukogu esimees on Hagi Šein

  14. Living Proof: What Helen Keller, Marilyn Monroe, and Marie Curie Have in Common.

    Science.gov (United States)

    Saul, E. Wendy

    1986-01-01

    Examines biographies of Marie Curie written for children and discusses two types of distortions: simple misrepresentations of fact and selective retelling of the past. It is concluded that biographies of minority or female success should deal specifically with strategies used by the hero or heroine to combat prejudice. (EM)

  15. Attracting Talented Researchers to Ireland: A review of The European Marie Curie Programme

    OpenAIRE

    Giordani, Silvia

    2007-01-01

    PUBLISHED The purpose of this publication is to illustrate how researchers in academia and industry in Ireland have successfully secured funding from Europe in the Marie Curie Programme and to highlight the impact this has had in furthering their R&D ambitions.

  16. The Gendering of Albert Einstein and Marie Curie in Children's Biographies: Some Tensions

    Science.gov (United States)

    Wilson, Rachel E.; Jarrard, Amber R.; Tippins, Deborah J.

    2009-01-01

    Few twentieth century scientists have generated as much interest as Albert Einstein and Marie Currie. Their lives are centrally depicted in numerous children's biographies of famous scientists. Yet their stories reflect interesting paradoxes and tacit sets of unexplored sociocultural assumptions about gender in science education and the larger…

  17. Hand involvement in children with Charcot-Marie-Tooth disease type 1A

    NARCIS (Netherlands)

    Burns, Joshua; Bray, Paula; Cross, Lauren A.; North, Kathryn N.; Ryan, Monique M.; Ouvrier, Robert A.

    2008-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A), a demyelinating neuropathy characterised by progressive length-dependent muscle weakness and atrophy, is thought to affect the foot and leg first followed some time later by hand weakness and dysfunction. We aimed to characterise hand Strength, function

  18. Response to Marie Paz Morales' ``Influence of culture and language sensitive physics on science attitude achievement''

    Science.gov (United States)

    Cole, Mikel Walker

    2015-12-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript.

  19. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  20. Acoustic Characteristics of Stressed Front Vowels in the French speech of Russian and Mari people

    Directory of Open Access Journals (Sweden)

    Зоя Георгиевна Зорина

    2014-12-01

    Full Text Available The article describes the spectral characteristics of stressed front vowels in the French speech of native speakers, Russian, Hill and Meadow Mari speakers under conditions of «artificial» bilingualism. Vowel spectra were determined by the F-picture (the first two formants. The research revealed that Russian and Mari native speakers demonstrate an ability to differentiate the rise of French vowels more frequently. Correct pronunciation of a number of French vowels is observed more frequently in the speech of the Hill Mari, more rarely- in the speech of the Meadow Mari. Russian speakers hardly differentiate vowel rows. However, the "poor" quality of speech in a foreign language does not prevent one from good understanding due to the fact that for a bilingual speaker the sounding of tokens on the morphemic level becomes less relevant than the meaning. Sufficiently deep immersion into lifestyle, behavior of speakers of another language can help achieve a real image of the picture of another language.

  1. Marie Underi ühe luuletuse ümber / August Eelmäe

    Index Scriptorium Estoniae

    Eelmäe, August, 1931-

    2003-01-01

    Marie Underi luuletusest "Me ootame" ja selle vaheredaktsioonist, avaldatud pealkirjaga "Üks päev" (Oma Maa, 1947, nr. 2). Ilmunud ka kogumikus: Eelmäe, August. Kõned ja kirjatööd. Tallinn : Underi ja Tuglase Kirjanduskeskus, 2006, lk. 56-71

  2. Principal Succession: A View through the Lens of Mary Douglas' Grid and Group

    Science.gov (United States)

    Mills, Angela

    2012-01-01

    Scope and Method of Study: This Naturalistic Inquiry Case Study examines principal succession at two small, rural high schools through naturalistic inquiry presented through the lens of Mary Douglas' grid and group cultural typology. A grid and group cultural analysis survey was sent to all school employees then in-depth, follow-up interviews…

  3. The Marie Curie programme at the Institute of Archaeology 2004-2008

    Directory of Open Access Journals (Sweden)

    Thilo Rehren

    2008-09-01

    Full Text Available The Marie Curie Early Stage Training (MEST projects, run by the European Commission, offer training opportunities to young scientists from EU member states and sometimes also from non-European countries. The Institute of Archaeology hosted one such project between 2004 and 2008, which is described here by its Principal Investigator.

  4. [PREGNANCY AND DELIVERY IN A PATIENT WITH CHARCOT-MARIE-TOOTH DISEASE].

    Science.gov (United States)

    Pehlivanov, B; Matev, M

    2016-01-01

    We report a case of a 34 years old primigravida with Charcot-Marie-Tooth disease (CMTD). The course of pregnancy was uneventful with no deterioration of symptoms due to the disease. Performed amniocentesis showed healthy fetus. Planned cesarean section with spinal anesthesia was performed because of the restricted pelvis. The possible issues of combination pregnancy and CMTD are discussed.

  5. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  6. Mary Lincoln's Madness: Understanding the Factors that Influence the Diagnosis and Treatment of Bipolar Disorder

    Science.gov (United States)

    Dick, Carina; Renes, Susan L.; Strange, Anthony T.

    2010-01-01

    Mary Lincoln, wife of President Abraham Lincoln, lived a tragic life. Beginning with the death of her mother when she was a little girl, Mrs. Lincoln experienced a number of family deaths, including three brothers, three sons, and the murder of her beloved husband while she sat by his side. In addition to tragedy, Mrs. Lincoln suffered from poor…

  7. Equivalence of ELSV and Bouchard-Mariño conjectures for r-spin Hurwitz numbers

    NARCIS (Netherlands)

    Shadrin, S.; Spitz, L.; Zvonkine, D.

    2015-01-01

    We propose two conjectures on Hurwitz numbers with completed (r+1)-cycles, or, equivalently, on certain relative Gromov-Witten invariants of the projective line. The conjectures are analogs of the ELSV formula and of the Bouchard-Mariño conjecture for ordinary Hurwitz numbers. Our r-ELSV formula is

  8. On the Differentiation of Mari and Permic Place Names in the Vetluga-Vyatka Interfluve Area

    Directory of Open Access Journals (Sweden)

    Alexander L. Pustyakov

    2014-12-01

    Full Text Available The article presents an analysis of place names of the Vetluga-Vyatka interfluve area containing lexemes that can be of either Mari or Permic origin. The paper focuses on the roots shVr, vazh ~ vozh which are frequent in the toponymy of the area, and some names ingluding the lexical component vad / vod / vot. The author establishes the linguistic attribution of the place names in question and suggests possible etymologies for the roots, determiners and names on the whole. In addition to the etymological analysis, the author shows the importance of some general and special principles of toponymic studies as applied to the differentiation of Mari and Permic place names of the Vetluga-Vyatka interfluve area. The author concludes that among the place names containing the component shVr there are those of both Mari and Permic origin, the latter being concentrated in the North-East of the Republic of Mari-El and in the adjacent districts of Kirov region. The author argues that the root vozh was not active in Udmurt toponymy when Udmurt clan groups lived on the right bank of the Vyatka. The article also suggests new hypotheses concerning the origin of some place names containing vad / vod / vot which used to be explained referring to the Komi language.

  9. Uus nobelist : prantslane Jean-Marie Gustave Le Clézio / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2008-01-01

    Nobeli kirjandusauhind 2008 - prantsuse romaanikirjanik Jean-Marie Gustave Le Clézio. Sisaldab autori eesti keelde tõlgitud teoste annotatsioone: Päev, mil Beaumont tegi tutvust oma valuga : [novell] / tlk. Merike Riives (kogumikust Prantsuse novell, 1973); Kõrb / tlk. Kristiina Ross (Eesti Raamat, 1990); Diego ja Frida / tlk. Sirje Keevallik (Kunst, 2007)

  10. PARTNER: A Marie Curie Initial Training Network for hadron therapy (with english subtitles)

    CERN Multimedia

    CERN BULLETIN; Manuela Cirilli; Nathalie Hospital

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  11. PARTNER: A Marie Curie Initial Training Network for hadron therapy (with french subtitles)

    CERN Document Server

    CERN BULLETIN; Manuela Cirilli; Nathalie Hospital

    2011-01-01

    PARTNER is a 4-year Marie Curie Training project funded by the European Commission with 5.6 million Euros aimed at the creation of the next generation of experts. Ten academic institutes and research centres and two leading companies are participating in PARTNER, that is coordinated by CERN, forming a unique multidisciplinary and multinational European network.

  12. Dysfunction in the hip joints in children with Charcot-Marie-Tooth syndrome (literature review

    Directory of Open Access Journals (Sweden)

    Иван Юрьевич Поздникин

    2015-09-01

    Full Text Available A review of the literature on the treatment of children with dysfunction in the hip joints in motor-sensory neuropathy Charcot-Marie-Tooth is presented. Peculiarities of disease diagnosis and the approach used in the treatment of patients are described. The Charcot-Marie-Tooth syndrome is a hereditary neuromuscular disease characterized by progressive atrophy of the distal muscle group of the lower limbs. According to international authors, the incidence of hip joint dysfunction in this condition is at least 10%, ranking second only to foot deformities. In the Russian literature, the problem has not been adequately interpreted. Early diagnosis of dysfunction in the hip joints during Charcot-Marie-Tooth syndrome is complicated by the child's age and is characterized by progression. Conflicting clinical signs and trivial symptoms of the disease also confuse diagnosis, until it becomes clearer in adolescence or the second or third decade of life. Surgical reconstructive operations on the hip joint often occur too late, and they are accompanied by a greater frequency of neurological complications. Practitioner awareness coupled with an early diagnosis of hip subluxation and decentration and complex orthopedic and neurological examinations of children with the disease of Charcot-Marie-Tooth should result in more favorable outcomes.

  13. Muuga / Mary von Grünewaldt ; tõlk. Mati Sirkel

    Index Scriptorium Estoniae

    Grünewaldt, Mary von

    2004-01-01

    Leo Zoegelt ostetud Muuga mõisahoone korrastamisest ja uue hoone ehitamisest C. T. von Neffi kunstikogu paigutamise tarbeks. Tütre mälestused. Tõlgitud raamatust: Skizzen und Bilder aus dem Leben Carl Timoleon von Neff / Mary von Grünewaldt. Darmstadt, 1887

  14. Assessing a Couple's Relationship and Compatibility Using the MARI[R] Card Test and Mandala Drawings

    Science.gov (United States)

    Frame, Phyllis G.

    2006-01-01

    This paper illustrates the use of the MARI[R] Card Test, a transpersonal assessment tool which includes archetypal designs and color choices, as well as the drawing of a white and black mandala, or circle picture, for assessing the compatibility of two people in a committed relationship. In an informal pilot research study, 22 couples were given…

  15. Women, Education and the Material Body Politic in Mary Wollstonecraft's "Vindications"

    Science.gov (United States)

    Bernath, Elizabeth

    2016-01-01

    This paper discusses Mary Wollstonecraft's "A Vindication of the Rights of Woman: With Strictures on Political and Moral Subjects" and "A Vindication of the Rights of Men" as books of philosophy about rational materialism. Based on an analysis of Lockean thought, as applied to the possibility of women's development of reason,…

  16. Mixed Messages: The Problem of Class in Mary Norton's "Borrowers" Series

    Science.gov (United States)

    Travis, Madelyn

    2007-01-01

    Scholars have posited various theories as to which sector of society Mary Norton's Borrowers most closely reflect, from exploitative aristocrats to helpless victims. Through social and literary contextualization, this article highlights the ways in which Norton represents social class in the series and explores the competing ideologies embedded in…

  17. Spatially detailed quantification of metal loading for decision making: Metal mass loading to American fork and Mary Ellen Gulch, Utah

    Science.gov (United States)

    Kimball, B.A.; Runkel, R.L.

    2009-01-01

    Effective remediation requires an understanding of the relative contributions of metals from all sources in a catchment, and that understanding must be based on a spatially detailed quantification of metal loading. A traditional approach to quantifying metal loading has been to measure discharge and chemistry at a catchment outlet. This approach can quantify annual loading and the temporal changes in load, but does not provide the needed spatial detail to evaluate specific sources, which is needed to support remediation decisions. A catchment or massloading approach provides spatial detail by combining tracer-injection and synoptic-sampling methods to quantify loading. Examples of studies in American Fork, Utah, and its tributary Mary Ellen Gulch illustrate this different approach. The mass-loading study in American Fork treated Mary Ellen Gulch as a single inflow. From that point of view, Mary Ellen Gulch was one of the greatest sources of Fe, Mn, Zn, and colloidal Pb loads to American Fork. But when Mary Ellen Gulch was evaluated in a separate catchment study, the detailed locations of metal loading were identified, and the extent of metal attenuation upstream from the mouth of Mary Ellen Gulch was quantified. The net, instantaneous load measured at the mouth of Mary Ellen Gulch for remediation planning would greatly underestimate the contributions of principal sources within the catchment. Extending the detailed sampling downstream from Mary Ellen Gulch indicated the possibility of diffuse groundwater inflow from Mary Ellen Gulch to American Fork. Comparing loads for Mary Ellen Gulch in the two studies indicates that metal loads could be substantially underestimated for planning purposes without the detailed catchment approach for the low-flow conditions in these studies. A mass-loading approach provides both the needed quantification of metal loading and the spatial detail to guide remediation decisions that would be the most effective in the catchments

  18. Pain assessment in Charcot-Marie-Tooth (CMT) disease.

    Science.gov (United States)

    Ribiere, C; Bernardin, M; Sacconi, S; Delmont, E; Fournier-Mehouas, M; Rauscent, H; Benchortane, M; Staccini, P; Lantéri-Minet, M; Desnuelle, C

    2012-04-01

    The objective of our study was to describe and evaluate the prevalence of chronic pain in persons with Charcot-Marie-Tooth (CMT) disease during a multidisciplinary consultation at the Center of Reference for Neuromuscular Diseases. This prospective study was conducted between 2008 and 2010, it was a partnership between a Center of Reference for Neuromuscular Diseases (Centre de référence des maladies neuromusculaires [CRMD]) and a Department for the Assessment and Treatment of Pain (Département d'évaluation et de traitement de la douleur [DETD]). The evaluation consisted in a complete assessment of each patient during the first multidisciplinary consultation, with a previously established diagnosis validated by genetic testing, by various specialists: neurologist, PM&R physician, pain management specialist and physiotherapist. The evaluation tools used were Visual Analogical Scale (VAS), Hospital Anxiety and Depression Scale (HAD), DN4 scale, Neuropathic Pain Symptom Inventory (NPSI) (if DN4≥4), Pain Questionnaire of Saint Antoine (QDSA) (if DN4painful areas, Overall Neuropathy Limitations Scale (ONLS), Medical Research Council scale (MRC), Short Questionnaire on Pain (QCD), VAS during transfers, self-care, getting dressed and physiotherapy sessions and quantified use of analgesics. A total of 50 patients were included (28 women, 22 men); two patients (one man and one woman) were discarded from the study because of missing pain assessment data. Mean age was 47years (R: 14-85), in average the symptoms had been present for the past 20years (R: 0.3-68), most patients had little impairment, the mean MRC was 53 (R: 36-60), with CMT1A being predominant (CMT1A: 76.9%, CMTX: 13.5%, CMT2: 5.8%, CMT4: 3.8%). It is noted that 65.4% of patients reported some pain with a mean duration of pain at 140months (R: 5-660). The mean VAS was 5.5 (R: 1-10), greater than 4 in 79.4% of cases, requiring the use of analgesics in 38.4% of cases (step 1: 60%, step 2: 40% on the WHO pain

  19. L’analyse culturelle de Mary Douglas : une contribution à la sociologie des institutions

    Directory of Open Access Journals (Sweden)

    Marcel Calvez

    2006-10-01

    Full Text Available L’analyse culturelle est un modèle d’analyse développé par Mary Douglas qui a pour objet de comparer les cultures à partir d’une analyse de la formation des institutions sociales. La présentation de cette approche se centre sur la typologie grid-group des institutions sociales. Elle en discute les fondations et les implications dans la prise en compte de la relation entre la structure sociale et l’action des individus.The Cultural Analysis of Mary Douglas: a Contribution to the Sociology of InstitutionsCultural analysis is an analytical model developed by Mary Douglas which aims to compare cultures based on analyzing the formation of their social institutions. In presenting this approach, this article focuses on a typology called the “grid-group” of social institutions. The author here examines the foundations and the implications of this typology by taking into account the relationship between social structure and individual action.El análisis cultural de Mary Douglas: contribución a la sociología de las institucionesEl análisis cultural es un modelo analítico desarrollado por Mary Douglas y tiene como objeto el comparar las culturas a partir del análisis de la formación de las instituciones sociales.  La presentación de esta aproximación está focalizada en la topología grid-group de las instituciones sociales. Reflexiona sobre los fundamentos y las implicaciones teniendo presente la relación entre la estructura social y la acción de los individuos.

  20. Congregations of the Children of Mary among female students of secondary schools in the Tarnów diocese

    Directory of Open Access Journals (Sweden)

    Edward Kabat

    1996-12-01

    Full Text Available Congregations of the Children of Mary were religious communities inextricably connected with the Sodality of Our Lady. The Sodality came into being through the Society of Jesus. At the request of the Father General Claudius Aquaviva, in 1584 Pope Gregory XIII issued a papal bull "Omnipotens Dei", in which he established the first Sodality of the Blessed Virgin Mary at the Collegio Romano. The Congregation of the Children of Mary was founded in Tarnów at the Ursuline Sisters' establishment (1877, who ran secondary schools until 1939.

  1. The Life of Mary Wollstonecroft and the Principles of Conduct Put Forward in "A Vindication of the Rights of Woman"

    OpenAIRE

    2009-01-01

    This paper examines the life of Mary Wollstonecraft (1759-1797), the wife of the philosopher William Goodwin and mother of Mary Shelley author of Frankenstein, through the prism of the principles of conduct set out in A Vindication of the Rights of Woman that Mary Wollstonecraft wrote over the period 1790 to 1792. In particular the paper focuses on the role of reason, virtue, and knowledge developed in A Vindication in establishing principles of conduct and the extent to which Mary’s own cond...

  2. Job performance in the mountain metros

    OpenAIRE

    Mark C. Snead; Kate Watkins

    2012-01-01

    This issue of the Rocky Mountain Economist explores the labor market performance of the mountain state metropolitan areas, including recent industry trends and comparisons to state and national job performance.

  3. Rocky Mountain Spotted Fever: Statistics and Epidemiology

    Science.gov (United States)

    ... The CDC Cancel Submit Search The CDC Rocky Mountain Spotted Fever (RMSF) Note: Javascript is disabled or ... please visit this page: About CDC.gov . Rocky Mountain Spotted Fever (RMSF) Symptoms, Diagnosis, and Treatment Statistics ...

  4. Cheyenne Mountain Air Force Station NPDES Permit

    Science.gov (United States)

    Under NPDES permit CO-0034762, the Cheyenne Mountain Air Force Station is authorized to discharge from the interior storm drainage system and air exhaust stacks at the Cheyenne Mountain Complex, in El Paso County, Colorado, to tributaries Fountain Creek.

  5. Yearly report, Yucca Mountain project

    Energy Technology Data Exchange (ETDEWEB)

    Brune, J.N.

    1992-09-30

    We proposed to (1) Develop our data logging and analysis equipment and techniques for analyzing seismic data from the Southern Great Basin Seismic Network (SGBSN), (2) Investigate the SGBSN data for evidence of seismicity patterns, depth distribution patterns, and correlations with geologic features (3) Repair and maintain our three broad band downhole digital seismograph stations at Nelson, nevada, Troy Canyon, Nevada, and Deep Springs, California (4) Install, operate, and log data from a super sensitive microearthquake array at Yucca Mountain (5) Analyze data from micro-earthquakes relative to seismic hazard at Yucca Mountain.

  6. Life in the Taihang Mountains

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    THE Taihang Mountain Range meanders for 500 kilometers across the territories of Henan, Shanxi and Hebei provinces. It is an important ecological screen for the North China Plain and source of water. In Hebei’s Shexian County sits Wangjinzhuang, a 300-year-old stone village nestled in the mountains.The village is a stone world-lanes, houses, court-yard walls, towers, pavilions, tables, benches and mills are all hewn fom ancient rock. Streets and lanes are paved in stones of various shapes and sizes whose sur-

  7. WHITE MOUNTAIN WILDERNESS, NEW MEXICO.

    Science.gov (United States)

    Segerstrom, Kenneth; Stotelmeyer, R.B.

    1984-01-01

    On the basis of a mineral survey the White Mountain Wilderness, which constitutes much of the western and northern White Mountains, New Mexico, is appraised to have six areas of probable mineral potential for base and precious metals. If mineral deposits exist in the wilderness, the potential is for small deposits of base and precious metals in veins and breccia pipes or, more significanlty, the possibility for large low-grade disseminated porphyry-type molybdenum deposits. There is little promise for the occurrence of geothermal energy resources in the area.

  8. ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Montecchiani, Celeste; Pedace, Lucia; Lo Giudice, Temistocle; Casella, Antonella; Mearini, Marzia; Gaudiello, Fabrizio; Pedroso, José L; Terracciano, Chiara; Caltagirone, Carlo; Massa, Roberto; St George-Hyslop, Peter H; Barsottini, Orlando G P; Kawarai, Toshitaka; Orlacchio, Antonio

    2016-01-01

    Charcot-Marie-Tooth disease is a group of hereditary peripheral neuropathies that share clinical characteristics of progressive distal muscle weakness and atrophy, foot deformities, distal sensory loss, as well as diminished tendon reflexes. Hundreds of causative DNA changes have been found, but much of the genetic basis of the disease is still unexplained. Mutations in the ALS5/SPG11/KIAA1840 gene are a frequent cause of autosomal recessive hereditary spastic paraplegia with thin corpus callosum and peripheral axonal neuropathy, and account for ∼ 40% of autosomal recessive juvenile amyotrophic lateral sclerosis. The overlap of axonal Charcot-Marie-Tooth disease with both diseases, as well as the common autosomal recessive inheritance pattern of thin corpus callosum and axonal Charcot-Marie-Tooth disease in three related patients, prompted us to analyse the ALS5/SPG11/KIAA1840 gene in affected individuals with autosomal recessive axonal Charcot-Marie-Tooth disease. We investigated 28 unrelated families with autosomal recessive axonal Charcot-Marie-Tooth disease defined by clinical, electrophysiological, as well as pathological evaluation. Besides, we screened for all the known genes related to axonal autosomal recessive Charcot-Marie-Tooth disease (CMT2A2/HMSN2A2/MFN2, CMT2B1/LMNA, CMT2B2/MED25, CMT2B5/NEFL, ARCMT2F/dHMN2B/HSPB1, CMT2K/GDAP1, CMT2P/LRSAM1, CMT2R/TRIM2, CMT2S/IGHMBP2, CMT2T/HSJ1, CMTRID/COX6A1, ARAN-NM/HINT and GAN/GAN), for the genes related to autosomal recessive hereditary spastic paraplegia with thin corpus callosum and axonal peripheral neuropathy (SPG7/PGN, SPG15/ZFYVE26, SPG21/ACP33, SPG35/FA2H, SPG46/GBA2, SPG55/C12orf65 and SPG56/CYP2U1), as well as for the causative gene of peripheral neuropathy with or without agenesis of the corpus callosum (SLC12A6). Mitochondrial disorders related to Charcot-Marie-Tooth disease type 2 were also excluded by sequencing POLG and TYMP genes. An additional locus for autosomal recessive Charcot-Marie

  9. Rocky Mountain Spotted Fever (For Parents)

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Rocky Mountain Spotted Fever KidsHealth > For Parents > Rocky Mountain Spotted Fever Print A A A What's in ... en español La rickettsiosis maculosa About RMSF Rocky Mountain spotted fever (RMSF) is a bacterial infection that's ...

  10. 49 CFR 71.8 - Mountain zone.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Mountain zone. 71.8 Section 71.8 Transportation Office of the Secretary of Transportation STANDARD TIME ZONE BOUNDARIES § 71.8 Mountain zone. The fourth zone, the mountain standard time zone, includes that part of the United States that is west of...

  11. 27 CFR 9.94 - Howell Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Howell Mountain. 9.94... Howell Mountain. (a) Name. The name of the viticultural area described in this section is “Howell Mountain.” (b) Approved maps. The appropriate maps for determining the boundaries of the Howell...

  12. Storymakers: Hopa Mountain's Early Literacy Program

    Science.gov (United States)

    Templin, Patricia A.

    2013-01-01

    Hopa Mountain's StoryMakers program is an innovative, research-based program for donating high quality young children's books to parents. Hopa Mountain is a nonprofit organization based in Bozeman, Montana. Hopa Mountain works with groups of rural and tribal citizen leaders who form StoryMakers Community Teams to talk one-on-one with local parents…

  13. 27 CFR 9.102 - Sonoma Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Sonoma Mountain. 9.102... Sonoma Mountain. (a) Name. The name of the viticultural area described in this section is “Sonoma Mountain.” (b) Approved maps. The approved maps for determining the boundary of the Sonoma...

  14. 27 CFR 9.112 - Arkansas Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Arkansas Mountain. 9.112... Arkansas Mountain. (a) Name. The name of the viticultural area described in this section is “Arkansas Mountain.” (b) Approved maps. The appropriate maps for determining the boundary of the Arkansas...

  15. Identificação diferencial de Rhodococcus equi e Dietzia maris em bubalinos Differential identification of Rhodococcus equi and Dietzia maris in buffaloes

    Directory of Open Access Journals (Sweden)

    L.R. Viana

    2009-08-01

    Full Text Available Foram analisados 24 isolados bacterianos oriundos de leite e pele de búfalas (Bubalus bubalis, os quais foram previamente identificados como Rhodococcus equi com o auxílio de fenotipia concisa. Testes fenotípicos complementares e ferramentas moleculares foram utilizados com o objetivo de caracterizar esses isolados, bem como diferenciá-los de outros microrganismos intimamente relacionados. Observaram-se três fenótipos distintos, porém a identificação dos isolados foi inconclusiva. Apenas um dos isolados foi comprovado como sendo R. equi com a realização da PCR espécie-específica, sequenciamento e análise dos fragmentos de DNA. Os demais isolados só foram identificados pelo sequenciamento de fragmento do gene que codifica a região 16S do rRNA universal de bactérias, indicando tratar-se de Dietzia maris. O perfil de susceptibilidade aos antimicrobianos revelou maior resistência dos isolados de D. maris para oxacilina (96% e rifampicina (87%. O isolado de R. equi apresentou resistência à amicacina, oxacilina, penicilina, rifampicina e tetraciclina. Alerta-se para o risco da incorreta identificação dos isolados baseados em testes fenotípicos concisos e para a necessidade de utilização de testes complementares para diferenciação entre R. equi e D. maris.Twenty-four bacterial isolates from milk and skin of buffalo females (Bubalus bubalis, which previously had been identified as Rhodococcus equi by using a restricted number of phenotypical tests for bacterial characterization, were analyzed. The goal of this study was to perform the characterization of these isolates, as well as the differentiation of other microorganisms closely related by using additional phenotypical tests and molecular tools. Based on the phenotypical results, three different biotypes were obtained. However, the identification of the isolates was inconclusive. Only one of the isolates was confirmed as R. equi by the PCR specifically for this species, as

  16. Marcel Mariën’s 'Woman Ajar'. A case of minor photography?

    Directory of Open Access Journals (Sweden)

    Mieke Bleyen

    2010-12-01

    Full Text Available

     

    Abstract (E: This paper examines Woman Ajar (1985, a late, largely forgotten photo book by Marcel Mariën, one of the key figures of Belgian post war surrealism. Representing the female body as fragmented and alienated by small objects, Mariën’s photographs balance between the private (amateurish and the public (professional and explores the fragile border between art and pornography. In addition, there is a sense of belatedness in them, which makes them particularly hard to label. This paper proposes the concept of minor photography, borrowed from Gilles Deleuze and Felix Guattari’s concept of a minor literature, as a valuable tool to approach Marcel Mariën’s work, which risks slipping through art history’s net.

    Abstract (F: Cet article examine Woman Ajar (1985, un livre de photographie tardif et largement oublié de Marcel Mariën, l’une des figures clés du surréalisme belge d’après-guerre. Représentant le corps féminin comme fragmenté et aliéné par de petits objets, les photographies de Mariën balancent entre les sphères privée (amateur et publique (professionnelle et explorent la frontière fragile entre l’art et la pornographie. En outre, il y a en elles un sens de la tardiveté, qui les rend particulièrement difficiles à étiqueter. Cet article propose le concept de photographie mineure, emprunté au concept de littérature mineure avancé par Gilles Deleuze et Félix Guattari, comme un outil précieux permettant d’approcher l’œuvre de Marcel Mariën, qui court le risque de glisser au travers du filet de l’histoire de l’art.

  17. Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater

    Directory of Open Access Journals (Sweden)

    Natalia Fernández

    2016-01-01

    Full Text Available Reseña de Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater, Waco (Texas, Baylor University Press, 2012, 173 pp. ISBN: 9781602586451.

  18. Mitochondrial DNA analysis on remains of a putative son of Louis XVI, King of France and Marie-Antoinette.

    Science.gov (United States)

    Jehaes, E; Decorte, R; Peneau, A; Petrie, J H; Boiry, P A; Gilissen, A; Moisan, J P; Van den Berghe, H; Pascal, O; Cassiman, J J

    1998-01-01

    Carl Wilhelm Naundorff was buried in 1845 in Delft as Louis Charles, Duc de Normandie, 'Louis XVII'. However, the son of Louis XVI and Marie-Antoinette-Louis XVII--officially died in the Temple of Paris in 1795. In order to resolve the identity of Naundorff, mitochondrial DNA (mtDNA) D-loop sequences of his remains were compared with the sequences obtained from the hairs of two sisters of Marie-Antoinette, Marie-Antoinette herself, and with the sequences obtained from DNA samples of two living maternal relatives. The mtDNA sequence of a bone sample from Naundorff showed two nucleotide differences from the sequences of the three sisters and four differences from the sequences of living maternal relatives. Based on this evidence it becomes very unlikely that Naundroff is the son of Marie-Antoinette.

  19. Recension de Chrisman-Campbell, "Fashion Victims. Dress at the Court of Louis XVI and Marie Antoinette"

    OpenAIRE

    Chery, Aurore

    2016-01-01

    International audience; Book review : Fashion Victims. Dress at the Court of Louis XVI and Marie-Antoinette. By Kimberly Chrisman-Campbell. New Haven: Yale University Press, 2015. ISBN 978-0-300-15438-2. 352 pp. £35.

  20. [Mari Uusküla. Basic colour terms in Finno-Ugric and Slavonic Languages] / Galina Paramei

    Index Scriptorium Estoniae

    Paramei, Galina

    2010-01-01

    Arvustus: Uusküla, Mari. Basic colour terms in Finno-ugric and Slavonic languages: myths and facts. Tartu : Tartu University Press, 2008. Dissertationes linguisticae Universitatis Tartuensis, 1406-5657 ; 9

  1. [Mari Laanemets. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978] / Mara Traumane

    Index Scriptorium Estoniae

    Traumane, Mara

    2013-01-01

    Arvustus: Laanemets, Mari. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978. (Humboldt-Schriften zur Kunst- und Bildgeschichte, Bd. 14.9 Berlin: Gebr. Mann 2011

  2. Mida arvatakse omavalitsustes koolivõrgu optimeerimisest? / Mart Järvik, Maris Liiders, Peeter Aas, Kaarin Veinbergs

    Index Scriptorium Estoniae

    2012-01-01

    Arvamust avaldasid Järvakandi vallavanem, Raplamaa omavalitsuste liidu esimees Mart Järvik, Harju maavalitsuse haridus- ja sotsiaalosakonna juhataja Maris Liiders, Põlva maavalitsuse haridus- ja sotsiaalosakonna juhataja Peeter Aas, Ida-Viru maavalitsuse haridus- ja sotsiaalosakonna juhataja Kaarin Veinbergs

  3. Mida arvatakse omavalitsustes koolivõrgu optimeerimisest? / Mart Järvik, Maris Liiders, Peeter Aas, Kaarin Veinbergs

    Index Scriptorium Estoniae

    2012-01-01

    Arvamust avaldasid Järvakandi vallavanem, Raplamaa omavalitsuste liidu esimees Mart Järvik, Harju maavalitsuse haridus- ja sotsiaalosakonna juhataja Maris Liiders, Põlva maavalitsuse haridus- ja sotsiaalosakonna juhataja Peeter Aas, Ida-Viru maavalitsuse haridus- ja sotsiaalosakonna juhataja Kaarin Veinbergs

  4. Armastus kui vale(m) : Mari Vihmandi ooperi "Armastuse valem" lavastusest Estonias / Ester Võsu ja Kristel Pappel

    Index Scriptorium Estoniae

    Võsu, Ester, 1975-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  5. [Mari Uusküla. Basic colour terms in Finno-Ugric and Slavonic Languages] / Galina Paramei

    Index Scriptorium Estoniae

    Paramei, Galina

    2010-01-01

    Arvustus: Uusküla, Mari. Basic colour terms in Finno-ugric and Slavonic languages: myths and facts. Tartu : Tartu University Press, 2008. Dissertationes linguisticae Universitatis Tartuensis, 1406-5657 ; 9

  6. [Mari Laanemets. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978] / Mara Traumane

    Index Scriptorium Estoniae

    Traumane, Mara

    2013-01-01

    Arvustus: Laanemets, Mari. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978. (Humboldt-Schriften zur Kunst- und Bildgeschichte, Bd. 14.9 Berlin: Gebr. Mann 2011

  7. A mountain of millipedes V

    DEFF Research Database (Denmark)

    Enghoff, Henrik

    2016-01-01

    Three new genera of Odontopygidae are described, all based on new species from the Udzungwa mountains, Tanzania, and all monotypic: Casuariverpa gen. nov. (type species: C. scarpa gen. et sp. nov.), Yia gen. nov. (type species: Y. geminispina gen. et sp. nov.), and Utiliverpa gen. nov. (type...

  8. A mountain of millipedes III

    DEFF Research Database (Denmark)

    Enghoff, Henrik

    2016-01-01

    The new genus Geotypodon gen. nov. is described. It includes two species from the Udzungwa Mountains: G. millemanus gen. et sp. nov. (type species) and G. submontanus gen. et sp. nov., one species from nearby Iringa: G. iringensis gen. et sp. nov., and 18 previously described species hitherto...

  9. Years Spent on Mountain Roads

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    SONG Fangrong, the Tu nationality girl who grew up drinking water from mountain springs, walked into the Great Hall of the People in Beijing to accept the highest prize for China’s youth—the "May 4th Youth Prize." Not long before, she had been named one of the National Ten Outstanding Youths. She is the only individual to have won both.

  10. Entretiens avec Marie Raynal, Redactrice em chef de Diversitè - France. Interview with Marie Raynal, editor of Diversité - France

    Directory of Open Access Journals (Sweden)

    Abramowicz, Anete

    2009-11-01

    Full Text Available A Revista Eletrônica de Educação teve o privilégio de entrevistar Marie Raynal, que apesar de muitas atividades nos concedeu um tempo para nos responder. Marie Raynal é Responsável pelo Departamento Ville-Ecole-Intégration (Cidade-Escola-Integração em Montrouge, França e Redatora Chefe (rédactrice em chef da Revista Diversité que é um dos únicos periódicos da educação na França que acolhe artigos sobre a diversidade social. Em 2003 foi criado o departamento “Ville & Education” sob a coordenação de Marie Raynal. Este departamento tem por missão acompanhar todos os atores da educação (professores, quadros da educação, coletividades, associações, etc. que tem por encargo - durante e fora do tempo escolar - as crianças e os jovens em situação de fragilidade, especialmente aqueles que vivem nos bairros da política da cidade, àqueles que se destacam por uma educação prioritária, os recém chegados na França e as crianças nômades. No conjunto destas questões, este departamento é considerado como expert nacional. Este departamento possui três revistas e uma carta de informação, entre elas está a revista trimestral em Ciências Sociais, a Diversité.The Revista Eletrônica de Educação (Electronic Journal of Education has the privilege to interview Marie Raynal, which although having many activities, dedicated us time to answer it. Marie Raynal is head of the Département de Ville-Ecole-Intégration (Department of City-School-Integration in Montrouge, France and Chief editor of the journal Diversité, which includes articles on social diversity. In 2003, the department "Ville & Education" is created under the authority of Marie Raynal. Its mission is to accompany all education members (teachers, education managers, communities, associations, etc. that are in charge, during and after school time, children and youth in situations of fragility, including those living in neighborhood of the city policy, those

  11. [Marie Curie, née Maria Sklodowska (1867-1934)--contribution to the development of radiology].

    Science.gov (United States)

    Babić, Rade R; Babić, Gordana Stanković

    2011-01-01

    Marie Curie, née Maria Sklodowska, was born on November 7, 1867 in Warsaw (Poland). She suffered from leukaemia and died on June 4, 1934. She was buried with full honours at Pantheon. Marie Curie and her husband Pierre Curie discovered the radioactive elements Polonium (84Po210), Thorium (90Th232) and Radium (88Ra226). Marie Curie introduced the term radioactivity into science. She was the first woman who got Ph.D. in France, the first woman professor at Sorbonne, Paris and Medical Academy. Of all the women who have ever won the Nobel Prize, Marie Curie was the only who received it twice. During World War I Marie Curie designed a mobile x-ray room "radiologic car". Marie Curie had an x-ray machine installed into a car and demonstrated how to use its dynamo for electric power production necessary for the x-ray machine to work. She had 20 cars with moving radiological lab made and trained 150 people to work on them. She brought something radically new into military medicine--mobile x-ray diagnostics. With the discovery of radioactive elements a new medical branch, radiotherapy, was developed.

  12. First stage of INTRAMAP: INtegrated Transantarctic Mountains and Ross Sea Area Magnetic Anomaly Project

    Directory of Open Access Journals (Sweden)

    D. Damaske

    1999-06-01

    Full Text Available INTRAMAP (INtegrated Transantarctic Mountains and Ross Sea Area Magnetic Anomaly Project is an international effort to merge the magnetic data acquired throughout the "Ross Sea Antarctic Sector" (south of 60°S between 135°-255°E including the Transantarctic Mountains (TAM, the Ross Sea, Marie Byrd Land, and the Pacific coast, and also to begin the compilation efforts for new data over the Wilkes Basin. This project is a component of the continental scale Antarctic Digital Magnetic Anomaly Project (ADMAP. The first stage of INTRAMAP addresses the analysis and merging of GITARA (1991-1994 and GANOVEX (1984 aeromagnetic surveys together with ground magnetic data (1984-1989. The combined data sets cover an area of approximately 30 km2 over Victoria Land and adjacent Ross Sea. Map and profile gridding were implemented to integrate the data sets. These approaches are studied for improving existing strategies to adopt for the whole magnetic compilation effort. The final microlevelled grid that we produce is a new tool for regional interpretation of the main tectonic and geologic features of this sector of Antarctica.

  13. O socialismo indígena de Mariátegui

    Directory of Open Access Journals (Sweden)

    Afonso Mancuso de Mesquita

    2012-05-01

    Full Text Available O indigenismo em Mariátegui só pode ser compreendido como socialismo indígena. Sua interpretação original da realidade peruana nos revela uma dupla heterodoxia, tanto do ponto de vista do indigenismo quanto da teoria socialista correntes em sua época. O primeiro defendia exclusivamente os elementos autóctones contra o poder imperialista e a segunda não reconhecia as particularidades latino-americanas na definição das tarefas revolucionárias Mariátegui, ao afirmar que o socialismo no Peru deveria ter como base as formas remanescentes de comunitarismo agrário indígena, supera ambas correntes e propõe uma síntese dialética ao pensar o socialismo peruano, condensada na proposição socialismo indo-americano.

  14. De Novo duplication in Charcot-Marie-Tooth Type 1A

    Energy Technology Data Exchange (ETDEWEB)

    Mandich, P.; Bellone, E.; Ajmar, F. [and others

    1996-09-01

    We read with interest the paper on {open_quotes}Prevalence and Origin of De Novo Duplications in Charcot-Marie-Tooth Disease Type 1A: First Report of a De Novo Duplication with a Maternal Origin,{close_quotes}. They reported their experience with 10 sporadic cases of Charcot-Marie-Tooth type 1A (CMT1A) in which it was demonstrated that the disease had arisen as the result of a de novo duplication. They analyzed the de novo-duplication families by using microsatellite markers and identified the parental origin of the duplication in eight cases. In one family the duplication was of maternal origin, whereas in the remaining seven cases it was of paternal origin. The authors concluded that their report was the first evidence of a de novo duplication of maternal origin, suggesting that this is not a phenomenon associated solely with male meiosis. 7 refs.

  15. Charcot-Marie-Tooth disease masquerading as acute demyelinating encephalomyelitis-like illness.

    Science.gov (United States)

    Kim, Gun-Ha; Kim, Kyoung Min; Suh, Sang-Il; Ki, Chang-Seok; Eun, Baik-Lin

    2014-07-01

    X-linked Charcot-Marie-Tooth disease (CMTX1) is a clinically heterogeneous hereditary motor and sensory neuropathy with X-linked transmission. Common clinical manifestations of CMTX1 disease, as in other forms of Charcot-Marie-Tooth (CMT) disease, are distal muscle wasting and weakness, hyporeflexia, distal sensory disturbance, and foot deformities. Mutations in the connexin-32 gene (gap junction protein β1 [GJB1]) are responsible for CMTX1 disease. In this report, we describe a patient with CMTX1 disease presenting with recurrent attacks of transient and episodic acute demyelinating encephalomyelitis (ADEM)-like symptoms without previous signs of lower extremity weakness or foot deformities; the patient, as well as his asymptomatic mother, exhibited a novel GJB1 mutation (p.Met1Ile). Differential diagnosis of recurrent and transient ADEM-like illness, if unexplained, should include the possibility of CMTX1 disease. Copyright © 2014 by the American Academy of Pediatrics.

  16. A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.

    Science.gov (United States)

    Gonzalez, Michael A; Feely, Shawna M; Speziani, Fiorella; Strickland, Alleene V; Danzi, Matt; Bacon, Chelsea; Lee, Youjin; Chou, Tsui-Fen; Blanton, Susan H; Weihl, Conrad C; Zuchner, Stephan; Shy, Michael E

    2014-11-01

    Mutations in VCP have been reported to account for a spectrum of phenotypes that include inclusion body myopathy with Paget's disease of the bone and frontotemporal dementia, hereditary spastic paraplegia, and 1-2% of familial amyotrophic lateral sclerosis. We identified a novel VCP mutation (p.Glu185Lys) segregating in an autosomal dominant Charcot-Marie-Tooth disease type 2 family. Functional studies showed that the Glu185Lys variant impaired autophagic function leading to the accumulation of immature autophagosomes. VCP mutations should thus be considered for genetically undefined Charcot-Marie-Tooth disease type 2. © The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. Reversible Foix-Chavany-Marie Syndrome in a patient treated for hydrocephalus.

    Science.gov (United States)

    Kaloostian, P; Chen, H; Harrington, H

    2012-10-01

    The authors report the first known case of Foix-Chavany-Marie Syndrome in a patient with hydrocephalus that reversed with ventriculoperitoneal shunting. A 34-year-old x-ray technician with a history of pilocytic astrocytoma resection and radiotherapy and ventriculoperitoneal shunt placement as a child presented with altered mental status and nausea. She was found to have acute hydrocephalus. Post-operatively she did well and was discharged home. The next day she became acutely altered with anarthria, difficulty speaking, and stiff facial muscles. After multiple revisions, she slowly recovered to her pre-op baseline over the course of next 2 months. This is the first known case of acute hydrocephalus causing Foix-Chavany-Marie Syndrome. Additionally, we show that this unique syndrome is slowly reversible after treatment of hydrocephalus.

  18. Concept And Its Implementation During The Reconstruction Of The Church Of Blessed Virgin Mary In Chojna

    Directory of Open Access Journals (Sweden)

    Płotkowiak Maciej

    2015-12-01

    Full Text Available St. Mary's parish church in Chojna was erected at the turn of XIV and XVc. in a shape of three aisles, hall church without transept, completed from the west with a single tower and from the east with polygonal presbytery with an ambulatory attached. The convergence of characteristic structural and decorative features with employed ones in medieval churches being attributed to Hinrich Brunsberg's fabric resulted in such a way, that also authorship of St. Mary in Chojna was assigned to this legendary architect and master builder of late Middle Ages period. The church was destroyed by fire during WWII in February 1945 and since then had remained as an open ruin. In 1997 reconstruction procedure of the church was begun under the leadership of the author and it still continues. This text consists of the sum of experiences connected with confronting design ideas and solutions with their executions on the site during construction works.

  19. Detection Performance of M-ary Relay Trees with Non-binary Message Alphabets

    CERN Document Server

    Zhang, Zhenliang; Pezeshki, Ali; Moran, William; Howard, Stephen D

    2012-01-01

    We study the detection performance of $M$-ary relay trees, where only the leaves of the tree represent sensors making measurements. The root of the tree represents the fusion center which makes an overall detection decision. Each of the other nodes is a relay node which aggregates $M$ messages sent by its child nodes into a new compressed message and sends the message to its parent node. Building on previous work on the detection performance of $M$-ary relay trees with binary messages, in this paper we study the case of non-binary relay message alphabets. We characterize the exponent of the error probability with respect to the message alphabet size $\\mathcal D$, showing how the detection performance increases with $\\mathcal D$. Our method involves reducing a tree with non-binary relay messages into an equivalent higher-degree tree with only binary messages.

  20. OCNELE MARI-OCNIŢA, VÂLCEA COUNTY RESOURCES, EXPLOITATION, RISKS, UTILISATION

    Directory of Open Access Journals (Sweden)

    P. GÂŞTESCU

    2015-03-01

    Full Text Available Ocnele Mari-Ocniţa. Resources, exploitation, risks, valorization. In Ocnele Mari Town and its constituent locality - Ocniţa, Vâlcea County, following the extraction of a large volume of salt through its underground dissolution, the soil and the breccias covering the salt have become unstable, producing landfalls and landslides that affected the exploitation installations, the transport infrastructure and several homes, during the last decennia, especially in the area of Ocniţa locality. In order to avoid major imbalances in this geographic area, following the mining activities, and also in order to reduce the consequences of the pollution triggered by saltwater, the main affected areas-locations have been identified and analyzed. This paper presents the resources existing in the exploitation area, the modifications occurred following the salt mining activities and their effects on: economic efficiency, local population, environmental balance, tourist potential and utilisation.

  1. The research school of Marie Curie in the Paris faculty, 1907-14.

    Science.gov (United States)

    Davis, J L

    1995-07-01

    As the most famous woman scientist of the twentieth century, there has been no shortage of books and articles on the life and career of Marie Curie (1867-1934). Her role as director of a laboratory-based research school in the new scientific field of radioactivity, a field which embraced both chemistry and physics, however, has never been examined. In recent years, there has been a growing interest in the question of research schools, and Morrell, Ravetz, Geison, and Klosterman, amongst others, have written on this subject. Using, in part, the methodology of Morrell, this paper investigates the role of Marie Curie as a school director in the Paris Faculty in the years 1907-14, examining the work and characteristics of her school and assessing her effectiveness as a director.

  2. An Unusual Cause for Sister Mary Joseph’s Nodule: A Case Report

    Directory of Open Access Journals (Sweden)

    Yasser Aljehani

    2014-11-01

    Full Text Available Sister Mary Joseph’s nodule refers to palpable nodules bulging into the umbilicus as a result of metastasis from malignancy in the abdomen or pelvis. The most common primaries are in the gastrointestinal or genital tract, while other origins are considered rare. We recently treated a 71-year-old man who presented with painless umbilical swelling. Further investigation, including laboratory, radiological and histopathological exam, confirmed the diagnosis of a metastatic neuroendocrine tumor. The peculiarity of this case is that the umbilical swelling was the initial presentation of a neuroendocrine tumor and, to our knowledge, this is the first to be reported. This case demonstrates that neuroendocrine tumor is a rare cause of Sister Mary Joseph’s nodule.

  3. Concept And Its Implementation During The Reconstruction Of The Church Of Blessed Virgin Mary In Chojna

    Science.gov (United States)

    Płotkowiak, Maciej

    2015-12-01

    St. Mary's parish church in Chojna was erected at the turn of XIV and XVc. in a shape of three aisles, hall church without transept, completed from the west with a single tower and from the east with polygonal presbytery with an ambulatory attached. The convergence of characteristic structural and decorative features with employed ones in medieval churches being attributed to Hinrich Brunsberg's fabric resulted in such a way, that also authorship of St. Mary in Chojna was assigned to this legendary architect and master builder of late Middle Ages period. The church was destroyed by fire during WWII in February 1945 and since then had remained as an open ruin. In 1997 reconstruction procedure of the church was begun under the leadership of the author and it still continues. This text consists of the sum of experiences connected with confronting design ideas and solutions with their executions on the site during construction works.

  4. Quelques aspects de la spiritualité conjugale selon Jean-Marie Lustiger

    Directory of Open Access Journals (Sweden)

    Ryszard Biernat

    2012-09-01

    Full Text Available In his pastoral teaching Jean-Marie Lustiger repeatedly explores the subject of marital spirituality. His teaching emerged as a response to young people’s difficulty in understanding the nature of marriage as a result of being immersed in the mentality of the world. In this article the author explores two important aspects of Cardinal Lustiger’s teaching on the spirituality of marriage: marriage is presented as a vocation and there is an emphasis on the correct understanding of marital love. In the context of the decline of religious practices in Western Europe, the article contains some of Jean-Marie Lustiger’s thoughts on the sacrament of marriage as well as his role in contributing to a deeper understanding of matrimony.

  5. The sugāgum in the Kingdom of Mari (XIX-XVIII BC. Diverging logics

    Directory of Open Access Journals (Sweden)

    Federico L. Luciani

    2013-07-01

    Full Text Available During the Old Babylonian period (ca. 2000-1600 BC., the Kingdom of Mari, on the Middle Euphrates river, excels due to the complexity of its ethnic and socio-political structure, in which distinctive elements typical of the state urban tradition and mobile herding groups -identified with tribal political practices- coexisted. Hence too the complexity of the socio-political relationships established within this society, relationships that need to be analysed without the prejudices that place nomad and sedentary people in unequal positions within an evolutionary scale. Throughout several letters from the Mari Royal Archive, it is possible to track the presence of the sugāgums submerged in the grid of these diverging logics, where they bore pliable posts. The aim of this paper is to inquire the flexibility of such posts

  6. Un conflicto matrimonial en el siglo XVIII: Henri de Vaucocour y Marie Boutinaud

    Directory of Open Access Journals (Sweden)

    Stéphane Minvielle

    2013-12-01

    Full Text Available El matrimonio en 1741 de dos miembros de la baja nobleza del suroeste de Francia, Henri de Vaucocour y Marie Boutinaud, desembocó, a partir de 1751, en un proceso judicial de separación. Los fondos documentales conservados sirven para analizar un conflicto matrimonial, las relaciones entre esposos, y las múltiples facetas de la violencia doméstica en la Francia del siglo XVIII

  7. PATIENT SAFETY CULTURE AND PATIENT SAFETY IMPLEMENTATION IN STELLA MARIS HOSPITAL DURING NATIONAL HEALTH INSURANCE ERA

    OpenAIRE

    Rivai, Fridawaty

    2017-01-01

    Implementation of patient safety in hospital is influenced by several factors such as culture of patient safety. The aim of the research was to analyze the effect of patient safety culture on the implementation of patient safety in Stella Maris Hospital in 2016. The research was a quantitative studyusinganalytic operationaldesign withcross-sectional approach. The samples consisted of 234people selected using proportional stratified random sampling technique. The results of the research ...

  8. Surgical Treatment of Scoliosis in Patients with Charcot-Marie-Tooth Disease

    Institute of Scientific and Technical Information of China (English)

    Farzad Omidi Kashani; Ibrahim Ghayem Hasankhani; Mahdi Banaii

    2009-01-01

    Objective: Apparently, scoliosis occurs in approximately one-third of patients with Charcot-Marie-Tooth disease. Little is known about the response of these curves to treatment. The purpose of this study was to evaluate the results of spinal surgery in these peculiar patients. Methods: We retrospectively evaluated the results of spinal surgery in eight patients who had scoliosis due to clinically and electrophysiologically proven Charcot-Marie-Tooth disease. Radiographs were reviewed. The location and direction of the curve pattern, the age at the time of surgery, type of surgery, number of levels fused, instrumentations used, intra or postoperative complications, and results and need for reoperation were recorded. Results: Eight patients associated with Charcot-Marie-Tooth disease who underwent scoliotic surgery were identified. The average age and curve at the time of surgery were 21.1 years and 56.4° respectively. 62.5% of the curves had left thoracic component and more than one third was associated with thoracic hyperkyphosis. Long posterior spinal fusion was performed most often, with an average of 11.5 spinal segments fused. Instrumentation was used in all posterior fusions. At an average of 39 months (range, 24 to 72 months) postoperatively, the fusion appeared to be solid in all patients. Conclusion: Scoliosis in patients with Charcot-Marie-Tooth disease differs from that in patients with idiopathic scoliosis in regarding to the etiology and the prevalence of thoracic hyperkyphosis, but the surgical management appears to be similar. Spondylodesis does not appear to be associated with a high rate of complications.

  9. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy

    Energy Technology Data Exchange (ETDEWEB)

    Fain, P.R.; Barker, D.F.; Chance, P.F. (Univ. of Utah, School of Medicine, Salt Lake City, UT (United States))

    1994-02-01

    Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.

  10. Feeling vs vorm. White label : Under Marie. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2007-01-01

    Rockansambli Chungin and the Strap-On-Faggots ja soome punkbändi Rejects kontserdist Tallinnas Reggae Baaris. Heliplaadist: Under Marie "1. What What? 2. What What?". Heliplaatidest: Zahir "Green means go", Ry Cooder "My name is Buddy", Ladysmith Black Mambazo "Warner Bros. Collection", Macy Gray "Big", Nneka "Victim of Truth", "Grinderman", Stooges "The Weirdness", "The Good, The Bad and the Queen", Marco Di Marco "In New York, My Poetry", Kaiser Chiefs "Yours Truly, Angry Mob", Mika "Life in cartoon motion"

  11. Reversible Foix–Chavany–Marie Syndrome in a patient treated for hydrocephalus

    OpenAIRE

    Kaloostian, P; H. Chen; Harrington, H

    2012-01-01

    The authors report the first known case of Foix-Chavany-Marie Syndrome in a patient with hydrocephalus that reversed with ventriculoperitoneal shunting. A 34-year-old x-ray technician with a history of pilocytic astrocytoma resection and radiotherapy and ventriculoperitoneal shunt placement as a child presented with altered mental status and nausea. She was found to have acute hydrocephalus. Post-operatively she did well and was discharged home. The next day she became acutely altered with an...

  12. Mary Ann Borina Radovich: Croatian Apple Farmer, Watsonville, California, 1918-1977

    OpenAIRE

    2004-01-01

    This oral history, conducted with Mary Ann Borina Radovich on June 7 and June 22, 1977, focuses on Radovich's extensive experience as an apple farmer in Watsonville, California from the 1930s to the 1970s. It is also a significant contribution to the ethnic history of the Croatian community in the Pajaro Valley of California. In this oral history Radovich discusses her family's history and their emigration to the United States. She describes the early apple industry in Watsonville, a...

  13. Mary Magdalen and the Imagery of Redemption: Reception and Revival in Fifteenth-Century Tyrol

    OpenAIRE

    Anderson, Joanne W.

    2015-01-01

    In 1384 a host miracle occurred in the Alpine church of Sankt Oswald in Seefeld. The perpetrator was publically humiliated and forced to repent for his sins, but the legend of his affront was to have lasting legacy in the visual culture of the church. While certain artworks have received critical attention for their retranslation of events, a fifteenth-century mural cycle depicting the life of Mary Magdalen, Christianity’s most perfect penitent, in the choir has been overlooked. This article ...

  14. Mary Wollstonecraft Shelley's Frankenstein, or the modern Prometheus: a psychological study of unrepaired shame.

    Science.gov (United States)

    Severino, Sally K; Morrison, Nancy K

    2013-01-01

    Mary Wollstonecraft Shelley's modern Prometheus shows us the eternal punishment of unrepaired shame--eternal entrapment within the shame triangle of victim, perpetrator and rescuer. This paper describes how Shelley's insight--that lack of love creates a monster living in shame--is being confirmed by neuroscience and how this is exemplified in two characters--the creature and Victor Frankenstein. Additionally, it delineates how pastoral counselors can help those suffering from unrepaired shame

  15. Insener Heinrich Laul ja Eesti XX sajandi ehituskultuur / Maris Suits, Carl-Dag Lige

    Index Scriptorium Estoniae

    Suits, Maris

    2010-01-01

    Näitus "Heinrich Laul 100" Tallinna Tehnikaülikoolis 10. sept.-4. okt. 2010. Näituse koostajad: Maris Suits (Eesti Kunstiakadeemia), Carl-Dag Lige (Helsingi Ülikool), Milvi Vahtra (TTÜ), näituse korraldajad: Signe Jantson ja Karl Õiger (TTÜ). Ehitusinsenerist ja -teadlasest Heinrich Laulust, tema tegevusest, seostest August Komendandiga. Koorikute koolkonnast ja teaduspõhisest ehituspraktikast. Tallinna laululavast. Seminarist ja H. Laulu artiklikogumikust

  16. Feeling vs vorm. White label : Under Marie. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2007-01-01

    Rockansambli Chungin and the Strap-On-Faggots ja soome punkbändi Rejects kontserdist Tallinnas Reggae Baaris. Heliplaadist: Under Marie "1. What What? 2. What What?". Heliplaatidest: Zahir "Green means go", Ry Cooder "My name is Buddy", Ladysmith Black Mambazo "Warner Bros. Collection", Macy Gray "Big", Nneka "Victim of Truth", "Grinderman", Stooges "The Weirdness", "The Good, The Bad and the Queen", Marco Di Marco "In New York, My Poetry", Kaiser Chiefs "Yours Truly, Angry Mob", Mika "Life in cartoon motion"

  17. Laparoscopic appendectomy in a pediatric patient with type 1 Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Heller, Joshua A; Marn, Richard Y

    2015-12-01

    A pediatric patient with type 1 Charcot-Marie-Tooth disease-a disorder associated with a demyelinating polyneuropathy-presented for laparoscopic appendectomy in the setting of acute appendicitis. Induction and maintenance of anesthesia were successfully managed without the use of any depolarizing or nondepolarizing neuromuscular blocking agents. The patient was successfully extubated at the completion of the procedure without any respiratory or neuromuscular sequelae, with excellent pain control and no postoperative nausea or vomiting.

  18. Fringe trees, Crump-Mode-Jagers branching processes and $m$-ary search trees

    OpenAIRE

    Holmgren, Cecilia; Janson, Svante

    2016-01-01

    This survey studies asymptotics of random fringe trees and extended fringe trees in random trees that can be constructed as family trees of a Crump-Mode-Jagers branching process, stopped at a suitable time. This includes random recursive trees, preferential attachment trees, fragmentation trees, binary search trees and (more generally) $m$-ary search trees, as well as some other classes of random trees. We begin with general results, mainly due to Aldous (1991) and Jagers and Nerman (1984). T...

  19. Central Nervous System Demyelination in a Charcot-Marie-Tooth Type 1A Patient

    OpenAIRE

    Christos Koros; Maria-Eleftheria Evangelopoulos; Costas Kilidireas; Elisabeth Andreadou

    2013-01-01

    Introduction. Central nervous system involvement, either clinical or subclinical, has been reported mainly in X-linked Charcot-Marie-Tooth (CMT-X) patients. Case Presentation. We present the case of a 31-year-old man with a genetically confirmed history of CMT1A who developed CNS involvement mimicking multiple sclerosis (MS). Clinical, imaging, and laboratory findings suggested an autoimmune CNS demyelination. Discussion. Although the simultaneous existence of CMT1A and MS could be coincident...

  20. Overlapping molecular pathological themes link Charcot-Marie-Tooth neuropathies and hereditary spastic paraplegias.

    Science.gov (United States)

    Timmerman, Vincent; Clowes, Virginia E; Reid, Evan

    2013-08-01

    In this review we focus on Charcot-Marie-Tooth (CMT) neuropathies and hereditary spastic paraplegias (HSPs). Although these diseases differ in whether they primarily affect the peripheral or central nervous system, both are genetically determined, progressive, long axonopathies that affect motor and sensory pathways. This commonality suggests that there might be similarities in the molecular pathology underlying these conditions, and here we compare the molecular genetics and cellular pathology of the two groups.

  1. "Spontaneous overflow of powerful feelings" : romantic imagery in Mary Shelley's Frankstein

    OpenAIRE

    Jaqueline Bohn Donada

    2006-01-01

    Romantic English literature – written at a time when prose fiction was predominantly a medium for sheer entertainment – is rooted in poetry. One or two novelists may exceptionally be granted the adjective “Romantic”, but Mary Shelley is not ranked among them. For centuries, her work has been restricted to that section in handbooks reserved for exotic Gothic literature. This thesis argues that literary criticism has failed to recognize Frankenstein’s obvious relation with the movement. The arg...

  2. The Historical Threshold : Crisis, Ritual and Liminality in Sofia Coppola’s Marie-Antoinette (2006

    Directory of Open Access Journals (Sweden)

    Anna Backman Rogers

    2012-10-01

    Full Text Available Marie Antoinette does not pertain to any of the narrative tropes and standards set by the conventional historical drama. Rather, it is a film about the politicisation of the female body. Its focus on the rite of passage of a young girl into adulthood in an extreme situation is, in effect, highly political both in its effort to convey a specifically female subjectivity and in its eschewal of a more traditional treatment of its subject matter.

  3. Best Practices Case Study: Pine Mountain Builders - Pine Mountain, GA

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-09-01

    Case study of Pine Mountain Builders who worked with DOE’s IBACOS team to achieve HERS scores of 59 on 140 homes built around a wetlands in Georgia. The team used taped rigid foam exterior sheathing and spray foam insulation in the walls and on the underside of the attic for a very tight 1.0 to 1.8 ACH 50 building shell.

  4. Charcot-Marie-Tooth disease and posterior scleritis: a case report Doença de Charcot-Marie-Tooth e esclerite posterior: relato de caso

    Directory of Open Access Journals (Sweden)

    Elisabeth N. Martins

    2000-10-01

    Full Text Available Purpose: To describe the unusual association of Charcot-Marie-Tooth disease (CMTD and posterior scleritis. Methods: Case report of a 16-year-old female with decreased visual acuity and pain in both eyes. Results: Ophthalmologic examination showed a posterior scleritis, confirmed by ultrasound and angiofluoresceinography. Foot deformities and sensory dysfunction were identified in the patient and some of her relatives. The diagnosis of CMTD in this patient was confirmed by eletrophysiologic studies. Conclusions: The association of posterior scleritis in a patient with CMTD has never been reported. This is also the first description of an inflammatory ocular disease in these patients.Objetivo: Descrever a associação entre doença de Charcot-Marie-Tooth (DCMT e esclerite posterior. Metodologia: Relato de caso de uma paciente do sexo feminino, 16 anos de idade, com baixa de acuidade visual e dor em ambos os olhos. Resultados: O exame oftalmológico revelou esclerite posterior, observada também por ultra-som e angiofluoresceinografia. Deformidades de pernas e pés foram identificadas na paciente e em seus familiares. O diagnóstico de DCMT na paciente estudada foi confirmado por estudos eletrofisiológicos. Conclusões: A presença de esclerite posterior em paciente com DCMT não é descrita na literatura, não se encontrando também relatos de outras doenças oculares inflamatórias, nestes pacientes.

  5. Charcot-Marie-Tooth病的研究与诊断进展%Progress of Research and Diagnosis of Charcot-Marie-Tooth Disease

    Institute of Scientific and Technical Information of China (English)

    朱琳; 胡静

    2011-01-01

    Charcot-Marie-Tooth disease(CMT) is % group of the most common familial peripheral neuropathies with highly genetic and clinical heterogeneity. CMT accounts for aboul 90% of hereditary neuropathies. CMT has similar clinical manifestations. Now there are at least .15 subtypes, which makes great difficulties in diagnosiing the disease. Therefore, this arliclc review;, the effective diagnostic methods of detailing the phenotypes and screening disease-related geres bused on the analysis of the clinical presentations, electrophysiology. Peripheral nerve pathology and causative genes of the subtypes of CMT.%Charcot-Marie-Tooth病,是一组最常见的在遗传和临床上都具有高度异质性的家族性周围神经病,约占全部遗传性神经病的90%.其基本临床表现相似,目前已知的亚型多达35种,为该病的确诊带来极大困难.因此,本文综述该病各亚型的临床、电生理、周围神经病理、致病基因及有效诊断方法.

  6. Mariátegui e a ocidentalização da política Mariátegui and the occidentalization of politics

    Directory of Open Access Journals (Sweden)

    Ricardo Melgar Bao

    2007-05-01

    Full Text Available A contribuição de Mariátegui para pensar o socialismo na América Latina é resgatada por meio das críticas à marginalização cultural e política dos povos não-ocidentais, bem como do particular uso que deu ao marxismo, acentuando-lhe as características universais através da apropriação cultural dos diversos contextos. Palavras-chave: América Latina. Oriente. Ocidente. Marxismo. Socialismo. Civilização. Cultura. Identidade. The contribution of Mariátequi for the view of socialism in Latin America is recovered not only through the criticism of the cultural and political marginal position of the non-western people but also through the particular way he used marxism, reinforcing its universal characteristics by the cultural appropriation of different cultural contexts. Keywords: Latin America. East. West. Marxism. Socialism. Civilization. Culture. Identity.

  7. Mary Shelley's Frankenstein: exploring neuroscience, nature, and nurture in the novel and the films.

    Science.gov (United States)

    Ginn, Sheryl R

    2013-01-01

    The story of Victor Frankenstein's quest to conquer death produced a legacy that has endured for almost 200 years. Powerful in its condemnation of the scientist's quest to achieve knowledge at any cost, Mary Shelley's Frankenstein is one of the most enduring novels of all time. It has never been out of print and has been translated to both stage and screen many times since its "birth." Numerous novels, short stories, and scripts have drawn upon Shelley's primary theme: the creation of a living organism from the dead, dying, and decaying body parts of human beings. Although Mary does not provide details of the animation process, particularly in her first edition, the process has been explored with a great deal of imagination and originality in the various cinematic portrayals of the story. Equally important as the theme of the scientist's quest for knowledge is the role that a creator plays in the life of its creation. Mary Shelley's novel pondered on how rejection would affect the offspring of such "unnatural" origins. In keeping with the "scientific" basis of the Creature's birth, cinematic portrayals attempted to provide a scientific rationale for the Creature's descent into madness and its evil behavior. From Robert Florey's initial script for the 1931 film directed by James Whale to the more recent films and television series, an abnormal brain is considered to be the cause of the madness and malignity of the Creature.

  8. XAS studies of the effectiveness of iron chelating treatments of Mary Rose timbers

    Energy Technology Data Exchange (ETDEWEB)

    Berko, A; Schofield, E J; Chadwick, A V [School of Physical Sciences, University of Kent, CT2 7NR (United Kingdom); Smith, A D [STFC Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Jones, A M [The Mary Rose Trust, HM Naval Base, Portsmouth, PO1 3LX (United Kingdom); Mosselmans, J F W, E-mail: a.berko@kent.ac.u [Diamond Light Source, Didcot, OX11 0DE (United Kingdom)

    2009-11-15

    The oxidation of sulfur in marine archaeological timbers under museum storage conditions is a recently identified problem, particularly for major artefacts such as historic ships excavated from the seabed. Recent work on the Vasa has stressed the role of iron in catalysing the oxidative degradation of the wood cellulose and the polyethylene glycols used to restore mechanical integrity to the timbers. In developing new treatment protocols for the long term preservation of Henry VIII of England's flagship, the Mary Rose, we are investigating the potential of chelating agents to neutralise and remove the iron products from the ships timbers. We have explored the use of aqueous solutions of chelating agents of calcium phytate, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA) and ammonium citrate to extract the iron compounds. All of these solutions exhibit some level of iron removal; however the key is to find the most effective concentration at pH of around 7 of the reagent solution, to minimise the treatment time and find the most cost-effective treatment for the whole of the Mary Rose hull. Fe K-edge XAFS data from samples of Mary Rose timbers, before and after treatment by the chelating agents mentioned has been collected. The data collected provide valuable insights into the effectiveness of the treatment solutions.

  9. XAS studies of the effectiveness of iron chelating treatments of Mary Rose timbers

    Science.gov (United States)

    Berko, A.; Smith, A. D.; Jones, A. M.; Schofield, E. J.; Mosselmans, J. F. W.; Chadwick, A. V.

    2009-11-01

    The oxidation of sulfur in marine archaeological timbers under museum storage conditions is a recently identified problem, particularly for major artefacts such as historic ships excavated from the seabed. Recent work on the Vasa has stressed the role of iron in catalysing the oxidative degradation of the wood cellulose and the polyethylene glycols used to restore mechanical integrity to the timbers. In developing new treatment protocols for the long term preservation of Henry VIII of England's flagship, the Mary Rose, we are investigating the potential of chelating agents to neutralise and remove the iron products from the ships timbers. We have explored the use of aqueous solutions of chelating agents of calcium phytate, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA) and ammonium citrate to extract the iron compounds. All of these solutions exhibit some level of iron removal; however the key is to find the most effective concentration at pH of around 7 of the reagent solution, to minimise the treatment time and find the most cost-effective treatment for the whole of the Mary Rose hull. Fe K-edge XAFS data from samples of Mary Rose timbers, before and after treatment by the chelating agents mentioned has been collected. The data collected provide valuable insights into the effectiveness of the treatment solutions.

  10. Mística revolucionaria: José Carlos Mariátegui y la religion

    Directory of Open Access Journals (Sweden)

    Michael Löwy

    2005-01-01

    Full Text Available En este artículo se presenta un perfil aproximado del pensamiento de Mariátegui en torno a la importancia de la religión para la filosofia marxista. Muy distanciado de la prácica dóctrinaria del marxismo ortodoxo sobre la «cuestión del hecho religioso», como ideología y «opio del pueblo», considera Mariátegui que se puede entender el socialismo como un hecho igualmente religioso desde el punto de vista de los valores que deben trascender al hombre. Señala que no todo es pura razón y ciencia, que es importante que los seres humanos se pregunten por la trascendencia. Forma parte esta concepción del marxismo en Mariátegui de su visión romántica de la revolución, utopista de la historia y agónica de la vida.

  11. An Overview of the MaRIE X-FEL and Electron Radiography LINAC RF Systems

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, Joseph Thomas III [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rees, Daniel Earl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Scheinker, Alexander [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sheffield, Richard L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-05-04

    The purpose of the Matter-Radiation Interactions in Extremes (MaRIE) facility at Los Alamos National Laboratory is to investigate the performance limits of materials in extreme environments. The MaRIE facility will utilize a 12 GeV linac to drive an X-ray Free-Electron Laser (FEL). Most of the same linac will also be used to perform electron radiography. The main linac is driven by two shorter linacs; one short linac optimized for X-FEL pulses and one for electron radiography. The RF systems have historically been the one of the largest single component costs of a linac. We will describe the details of the different types of RF systems required by each part of the linacs. Starting with the High Power RF system, we will present our methodology for the choice of RF system peak power and pulselength with respect to klystron parameters, modulator parameters, performance requirements and relative costs. We will also present an overview of the Low Level RF systems that are proposed for MaRIE and briefly describe their use with some proposed control schemes.

  12. Microbial activity at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Horn, J.M.; Meike, A.

    1995-09-25

    The U.S. Department of Energy is engaged in a suitability study for a potential geological repository at Yucca Mountain, Nevada, for the containment and storage of commercially generated spent fuel and defense high-level nuclear waste. There is growing recognition of the role that biotic factors could play in this repository, either directly through microbially induced corrosion (MIC), or indirectly by altering the chemical environment or contributing to the transport of radionuclides. As a first step toward describing and predicting these processes, a workshop was held on April 10-12, 1995, in Lafayette, California. The immediate aims of the workshop were: (1) To identify microbially related processes relevant to the design of a radioactive waste repository under conditions similar to those at Yucca Mountain. (2) To determine parameters that are critical to the evaluation of a disturbed subterranean environment. (3) To define the most effective means of investigating the factors thus identified.

  13. DISCONTINUITIES AND INADVERTENCES IN MOUNTAIN

    Directory of Open Access Journals (Sweden)

    VASILESCU RAMONA VIOLETA

    2013-05-01

    Full Text Available For some, mountain outings represent hikes; for some – rock climbing, and for others they consist of staying in a pension or hotel, while enjoying a pool in addition to the comfort of their home. This paper considers hiking enthusiasts, especially those who set off from their camp in the morning and return to their tent or nonluxurious accommodation in the evening.

  14. Thunderstorms, Andean Mountains Ridgeline, Argentina

    Science.gov (United States)

    1993-01-01

    In this scenic view of thunderstorms skirting the eastern ridgeline of the Andeas Mountains in northern Argentina (approximate coordinates 28.0S, 57.0W), the confluence of the Rio Salado and Rio Saladillo where they merge with the Rio Parana can be seen in sunglint. Thunderstorms along the eastern Andes are typical at this time of year (Southern Hemisphere summer) with anvils moving to the east from the core of the storm.

  15. Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Sevilla, Teresa; Lupo, Vincenzo; Martínez-Rubio, Dolores; Sancho, Paula; Sivera, Rafael; Chumillas, María J; García-Romero, Mar; Pascual-Pascual, Samuel I; Muelas, Nuria; Dopazo, Joaquín; Vílchez, Juan J; Palau, Francesc; Espinós, Carmen

    2016-01-01

    Charcot-Marie-Tooth disease (CMT) is a complex disorder with wide genetic heterogeneity. Here we present a new axonal Charcot-Marie-Tooth disease form, associated with the gene microrchidia family CW-type zinc finger 2 (MORC2). Whole-exome sequencing in a family with autosomal dominant segregation identified the novel MORC2 p.R190W change in four patients. Further mutational screening in our axonal Charcot-Marie-Tooth disease clinical series detected two additional sporadic cases, one patient who also carried the same MORC2 p.R190W mutation and another patient that harboured a MORC2 p.S25L mutation. Genetic and in silico studies strongly supported the pathogenicity of these sequence variants. The phenotype was variable and included patients with congenital or infantile onset, as well as others whose symptoms started in the second decade. The patients with early onset developed a spinal muscular atrophy-like picture, whereas in the later onset cases, the initial symptoms were cramps, distal weakness and sensory impairment. Weakness and atrophy progressed in a random and asymmetric fashion and involved limb girdle muscles, leading to a severe incapacity in adulthood. Sensory loss was always prominent and proportional to disease severity. Electrophysiological studies were consistent with an asymmetric axonal motor and sensory neuropathy, while fasciculations and myokymia were recorded rather frequently by needle electromyography. Sural nerve biopsy revealed pronounced multifocal depletion of myelinated fibres with some regenerative clusters and occasional small onion bulbs. Morc2 is expressed in both axons and Schwann cells of mouse peripheral nerve. Different roles in biological processes have been described for MORC2. As the silencing of Charcot-Marie-Tooth disease genes have been associated with DNA damage response, it is tempting to speculate that a deregulation of this pathway may be linked to the axonal degeneration observed in MORC2 neuropathy, thus adding a

  16. Diagnostic laboratory testing for Charcot Marie Tooth disease (CMT): the spectrum of gene defects in Norwegian patients with CMT and its implications for future genetic test strategies

    National Research Council Canada - National Science Library

    Østern, Rune; Fagerheim, Toril; Hjellnes, Helene; Nygård, Bjørn; Mellgren, Svein I; Nilssen, Øivind

    2013-01-01

    Current genetic test algorithms for Charcot Marie Tooth (CMT) disease are based on family details and comprehensive clinical and neurophysiological data gathered under ideal conditions for clinical assessment...

  17. Resources, tourism and mountain territorial development

    Directory of Open Access Journals (Sweden)

    2012-02-01

    Full Text Available Rationale and objectivesThe Journal of Alpine Research is preparing a special issue dedicated to the theme “Resources”, tourism and mountain territorial development.” The objective is to bring together analyses concerning the identification, “invention,” communication and exploitation of territorial resources in development initiatives including tourism in African and European mountainous regions, or beyond. It will particularly stress the capacity of referring to “mountains,” as a generic ca...

  18. On the Mountain Urban Landscape Studies

    Institute of Scientific and Technical Information of China (English)

    DU ChunLan

    2009-01-01

    Mountain Urban Landscape Studies is a discipline to research on the formation, evolution and char-acteristics of the urban landscape in mountainous areas. The author has made systematic research on the basic issues of the subject, including the definition of mountain urban landscape studies, its con-notation and denotation, the research scope, research background and significance, research meth-odology, its relationship with landscape architecture, architecture, city planning and other disciplines.

  19. On the Mountain Urban Landscape Studies

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Mountain Urban Landscape Studies is a discipline to research on the formation,evolution and characteristics of the urban landscape in mountainous areas. The author has made systematic research on the basic issues of the subject,including the definition of mountain urban landscape studies,its connotation and denotation,the research scope,research background and significance,research methodology,its relationship with landscape architecture,architecture,city planning and other disciplines.

  20. Location Awareness in a Mountain Rescue Domain

    OpenAIRE

    Georgopoulos, Panagiotis; Edwards, Christopher; Dunmore, Martin

    2008-01-01

    Aiding the efficient collaboration and coordination of rescue teams is a challenging task especially in a heterogeneous mountainous region. Knowing the exact location of the rescuers during a mountain search and rescue mission can be of great value for the successful progress of the mission and help the mission coordinator in taking informed decisions. The devised Location Awareness System can provide, in a quasi real time manner, exact location information of the rescuers on the mountain, to...

  1. Fouffeen Mountain Summits:the Dreams and Glory of Chinese Mountaineers

    Institute of Scientific and Technical Information of China (English)

    DORJE; DRADUL

    2007-01-01

    As the first mountaineering team to challenge the fourteen world's highest mountain summits,these Chinese mountaineers have finally realized their dream.They are all ethnic Tibetans and have gone through hardship and dangers over the years;some of them have even contributed their lives to the realization of the project.Finally,three of them have accomplished it and set a marvelous record in world mountaineering that is unprecedented.

  2. Landscape, Mountain Worship and Astronomy in Socaire

    Science.gov (United States)

    Moyano, Ricardo

    The spatiotemporal analysis of mountain worship in the indigenous community of Socaire, Atacama, northern Chile, relates to cultural, geographical, climatic, psychological, and astronomical information gathered from ethno archaeological studies. We identify a system of offerings to the mountains that incorporates concepts such as ceque (straight line), mayllku (mountain lord or ancestor), and pacha (space and time). Here, the mountains on the visible horizon (Tumisa, Lausa, Chiliques, Ipira, and Miñiques) feature as the fingers on the left hand (PAH Triad). This structure regulates annual activities and rituals and sets the basis for the Socaireños' worldview raised on a humanized landscape.

  3. A rat model of Charcot-Marie-Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients.

    Science.gov (United States)

    Fledrich, Robert; Schlotter-Weigel, Beate; Schnizer, Tuuli J; Wichert, Sven P; Stassart, Ruth M; Meyer zu Hörste, Gerd; Klink, Axel; Weiss, Bernhard G; Haag, Uwe; Walter, Maggie C; Rautenstrauss, Bernd; Paulus, Walter; Rossner, Moritz J; Sereda, Michael W

    2012-01-01

    Charcot-Marie-Tooth disease is the most common inherited neuropathy and a duplication of the peripheral myelin protein 22 gene causes the most frequent subform Charcot-Marie-Tooth 1A. Patients develop a slowly progressive dysmyelinating and demyelinating peripheral neuropathy and distally pronounced muscle atrophy. The amount of axonal loss determines disease severity. Although patients share an identical monogenetic defect, the disease progression is strikingly variable and the impending disease course can not be predicted in individual patients. Despite promising experimental data, recent therapy trials have failed. Established clinical outcome measures are thought to be too insensitive to detect amelioration within trials. Surrogate biomarkers of disease severity in Charcot-Marie-Tooth 1A are thus urgently needed. Peripheral myelin protein 22 transgenic rats harbouring additional copies of the peripheral myelin protein 22 gene ('Charcot-Marie-Tooth rats'), which were kept on an outbred background mimic disease hallmarks and phenocopy the variable disease severity of patients with Charcot-Marie-Tooth 1A. Hence, we used the Charcot-Marie-Tooth rat to dissect prospective and surrogate markers of disease severity derived from sciatic nerve and skin tissue messenger RNA extracts. Gene set enrichment analysis of sciatic nerve transcriptomes revealed that dysregulation of lipid metabolism associated genes such as peroxisome proliferator-activated receptor gamma constitutes a modifier of present and future disease severity. Importantly, we directly validated disease severity markers from the Charcot-Marie-Tooth rats in 46 patients with Charcot-Marie-Tooth 1A. Our data suggest that the combination of age and cutaneous messenger RNA levels of glutathione S-transferase theta 2 and cathepsin A composes a strong indicator of disease severity in patients with Charcot-Marie-Tooth 1A, as quantified by the Charcot-Marie-Tooth Neuropathy Score. This translational approach

  4. Christine HIVET, Voix de femmes : roman féminin et condition féminine de Mary Wollstonecraft à Mary Shelley, Presses de l'Ecole Normale Supérieure, Paris, 1997.

    OpenAIRE

    2003-01-01

    L'étude de Christine Hivet concerne deux romancières, la mère et la fille, Mary Wollstonecraft (1759-1797) et Mary Godwin Shelley (1797-1851), situées à la jonction des XVIII et XIXe siècles. Hivet examine la première dans le contexte du modèle féminin esquissé par quelques romancières de seconde zone, émules ou adversaires de notre aïeule féministe. En parallèle et en contrepoint, elle étudie la seconde, Mary Shelley. Celle-ci s'exprime dans des œuvres de science-fiction (Frankenstein...

  5. A mountain of millipedes I

    DEFF Research Database (Denmark)

    Enghoff, Henrik

    2014-01-01

    Twenty new species of the millipede genus Chaleponcus Attems, 1914, are described from the Udzungwa Mountains: C. netus sp. nov., C. quasimodo sp. nov., C. malleolus sp. nov., C. scopus sp. nov., C. nikolajscharffi sp. nov., C. mwanihanensis sp. nov., C. basiliscus sp. nov., C. krai sp. nov., C. ...... and unusual tarsal setation of a few species tentatively suggest adaptive radiation......., they constitute the Chaleponcus dabagaensis-group, well characterized by apparently apomorphic gonopodal characters, presumably monophyletic, and the first example of a major radiation within the Udzungwas. All species are restricted to altitudes >1390 m, all but one were found in only one, rarely two forest...

  6. Cascade Mountain Range in Oregon

    Science.gov (United States)

    Sherrod, David R.

    2016-01-01

    The Cascade mountain system extends from northern California to central British Columbia. In Oregon, it comprises the Cascade Range, which is 260 miles long and, at greatest breadth, 90 miles wide (fig. 1). Oregon’s Cascade Range covers roughly 17,000 square miles, or about 17 percent of the state, an area larger than each of the smallest nine of the fifty United States. The range is bounded on the east by U.S. Highways 97 and 197. On the west it reaches nearly to Interstate 5, forming the eastern margin of the Willamette Valley and, farther south, abutting the Coast Ranges. 

  7. OS X Mountain Lion bible

    CERN Document Server

    Gruman, Galen

    2012-01-01

    The complete guide to Mac OS X, fully updated for the newest release! The Mac's solid, powerful operating system and the exploding popularity of iOS devices are fueling a strong increase in market share for Apple. Previous editions of this book have sold more than 75,000 copies, and this new edition is fully updated with all the exciting features of OS X Mountain Lion, including Game Center, Messages, and Notifications. Written by industry expert Galen Gruman, it covers all the basics and then delves deep into professional and higher-end topics, making it the one book you need to succeed with

  8. Marys Lake 69/115-kV transmission line upgrade and substation expansion projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    Western Area Power Administration (Western) and the Platte River Power Authority (Platte River) propose to upgrade portions of the existing electric transmission and substation system that serves the Town of Estes Park, Colorado. The existing transmission lines between the Estes Power Plant Switchyard and the Marys Lake Substation include a 115,000 volt (115-kV) line and 69,000 volt (69-kV) line. Approximately one mile is a double-circuit 115/69-kV line on steel lattice structures, and approximately two miles consists of separate single-circuit 115-kV and a 69-kV lines, constructed on wood H-Frame structures. Both lines were constructed in 1951 by the US Bureau of Reclamation. The existing transmission lines are on rights-of-way (ROW) that vary from 75 feet to 120 feet and are owned by Western. There are 48 landowners adjacent to the existing ROW. All of the houses were built adjacent to the existing ROW after the transmission lines were constructed. Upgrading the existing 69-kV transmission line between the Marys Lake Substation and the Estes Power Plant Switchyard to 115-kV and expanding the Marys Lake Substation was identified as the most effective way in which to improve electric service to Estes Park. The primary purpose and need of the proposed project is to improve the reliability of electric service to the Town of Estes Park. Lack of reliability has been a historical concern, and reliability will always be less than desired until physical improvements are made to the electrical facilities serving Estes Park.

  9. The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Niemann, Axel; Huber, Nina; Wagner, Konstanze M; Somandin, Christian; Horn, Michael; Lebrun-Julien, Frédéric; Angst, Brigitte; Pereira, Jorge A; Halfter, Hartmut; Welzl, Hans; Feltri, M Laura; Wrabetz, Lawrence; Young, Peter; Wessig, Carsten; Toyka, Klaus V; Suter, Ueli

    2014-03-01

    The ganglioside-induced differentiation-associated protein 1 (GDAP1) is a mitochondrial fission factor and mutations in GDAP1 cause Charcot-Marie-Tooth disease. We found that Gdap1 knockout mice (Gdap1(-/-)), mimicking genetic alterations of patients suffering from severe forms of Charcot-Marie-Tooth disease, develop an age-related, hypomyelinating peripheral neuropathy. Ablation of Gdap1 expression in Schwann cells recapitulates this phenotype. Additionally, intra-axonal mitochondria of peripheral neurons are larger in Gdap1(-/-) mice and mitochondrial transport is impaired in cultured sensory neurons of Gdap1(-/-) mice compared with controls. These changes in mitochondrial morphology and dynamics also influence mitochondrial biogenesis. We demonstrate that mitochondrial DNA biogenesis and content is increased in the peripheral nervous system but not in the central nervous system of Gdap1(-/-) mice compared with control littermates. In search for a molecular mechanism we turned to the paralogue of GDAP1, GDAP1L1, which is mainly expressed in the unaffected central nervous system. GDAP1L1 responds to elevated levels of oxidized glutathione by translocating from the cytosol to mitochondria, where it inserts into the mitochondrial outer membrane. This translocation is necessary to substitute for loss of GDAP1 expression. Accordingly, more GDAP1L1 was associated with mitochondria in the spinal cord of aged Gdap1(-/-) mice compared with controls. Our findings demonstrate that Charcot-Marie-Tooth disease caused by mutations in GDAP1 leads to mild, persistent oxidative stress in the peripheral nervous system, which can be compensated by GDAP1L1 in the unaffected central nervous system. We conclude that members of the GDAP1 family are responsive and protective against stress associated with increased levels of oxidized glutathione.

  10. A novel transgenic mouse model of Chinese Charcot-Marie-Tooth disease type 2L

    Institute of Scientific and Technical Information of China (English)

    Ruxu Zhang; Qian Pan; Beisha Tang; Fufeng Zhang; Xiaobo Li; Shunxiang Huang; Xiaohong Zi; Ting Liu; Sanmei Liu; Xuning Li; Kun Xia

    2014-01-01

    We previously found that the K141N mutation in heat shock protein B8 (HSPB8) was respon-sible for Charcot-Marie-Tooth disease type 2L in a large Chinese family. The objective of the present study was to generate a transgenic mouse model bearing the K141N mutation in the human HSPB8 gene, and to determine whether this K141NHSPB8 transgenic mouse model would manifest the clinical phenotype of Charcot-Marie-Tooth disease type 2L, and consequently be suitable for use in studies of disease pathogenesis. Transgenic mice overexpressing K141NHSPB8 were generated using K141N mutant HSPB8 cDNA cloned into a pCAGGS plasmid driven by a human cytomegalovirus expression system. PCR and western blot analysis conifrmed integra-tion of the K141NHSPB8 gene and widespread expression in tissues of the transgenic mice. The K141NHSPB8 transgenic mice exhibited decreased muscle strength in the hind limbs and impaired motor coordination, but no obvious sensory disturbance at 6 months of age by behavioral assess-ment. Electrophysiological analysis showed that the compound motor action potential amplitude in the sciatic nerve was signiifcantly decreased, but motor nerve conduction velocity remained normal at 6 months of age. Pathological analysis of the sciatic nerve showed reduced myelinated ifber density, notable axonal edema and vacuolar degeneration in K141NHSPB8 transgenic mice, suggesting axonal involvement in the peripheral nerve damage in these animals. These ifndings indicate that the K141NHSPB8 transgenic mouse successfully models Charcot-Marie-Tooth disease type 2L and can be used to study the pathogenesis of the disease.

  11. La tesis de Mariátegui sobre el carácter feudal de la economía colonial peruana Mariátegui's thesis on the feudal character of Peruvian colonial economy

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    2010-06-01

    Full Text Available José Carlos Mariátegui, en su "Esquema de la evolución económica" [del Perú], el primero de los 7 ensayos (1928, consideró que la economía colonial peruana era feudal. En nuestro libro El marxismo de Mariátegui y su aplicación a los '7 ensayos (2005', manifestamos que con la información disponible hoy, tal afirmación se había tornado insostenible. Por su parte, Antonio Melis señaló que la caracterización de Mariátegui podía ser discutida. En este artículo se examinan las observaciones planteadas por Melis. Se considera en primer lugar la posición de A. G. Frank, así como las reacciones que suscitó. Se exponen a continuación las razones en contra de la tesis de Mariátegui sobre el carácter feudal de la economía peruana colonial. Se examina luego la tesis de Ruggiero Romano sobre el feudalismo en general y sobre el iberoamericano en particular. Se realiza, por último, una consideración final.José Carlos Mariátegui, in his "Outline of economic evolution" [Peru], the first of the 7 ensayos (1928, considered Peru's colonial economy was feudal. In our book Mariátegui's Marxism and its application to '7 ensayos' (2005, we said that the information available today, such a claim had become untenable. For his part, Antonio Melis said Mariátegui's characterization could be discussed. This article discusses the observation raised by Melis. It considers the position of A. G. Frank, as well as the reactions to it. Then the reasons against Mariátegui's thesis are also considered. The thesis on feudalism in general and the Latin American one in particular is examined by Ruggiero Romano. A final one consideration is done as a conclusion.

  12. Marie Darrieussecq, Rapporto di polizia. Le accuse di plagio e altri metodi di controllo della scrittura

    Directory of Open Access Journals (Sweden)

    Niccolò Scaffai

    2012-04-01

    Full Text Available A Marie Darrieussecq è successo qualcosa di strano. Non è il fatto di essere nata in Francia, a Bayonne, nel 1969. Né di essere una scrittrice (oltre che una studiosa di letteratura e una psicanalista, che ha pubblicato fiction, racconti autobiografici, saggi letterari. Questo non è così strano. Lo è invece il fatto che metà dei suoi romanzi siano stati considerati, da lettori diversi e soprattutto da altri scrittori, prodotti di «imitazione», «copia», «plagio psichico», o addirittura di «sottrazione di manoscritto»

  13. Pes Cavus and Charcot Marie Tooth Disease: A Case Report and Brief Review of the Literature

    Directory of Open Access Journals (Sweden)

    Levent Ediz

    2011-09-01

    Full Text Available Charcot-Marie-Tooth (CMT is a disease that is highly heterogeneous, both clinically and genetically. Clinical and electrophysiological data are essential for diagnosis. Children with CMT experience acquired foot weakness, contracture and deformity (pes cavus and hammer toes from an early age. Early intervention targeting the foot and ankle may prevent long-term disability in CMT. Here we present a CMT patient with acquired pes cavus and hammer toes and review the literature briefly for diagnosis, treatment, and rehabilitation of CMT. As a result we conclude that CMT should also come into mind in the differential diagnosis of acquired pes cavus and hammer toes.

  14. Geothermal heating project at St. Mary's Hospital, Pierre, South Dakota. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-12-01

    St. Mary's Hospital, Pierre, South Dakota, with the assistance of the US Department of Energy, drilled a 2176 ft well into the Madison Aquifer ot secure 108/sup 0/F artesian flow water at 385 gpm (475 psig shut-in pressure). The objective was to provide heat for domestic hot water and to space heat 163,768 sq. ft. Cost savings for the first three years were significant and, with the exception of a shutdown to replace some corroded pipe, the system has operated reliably and continuously for the last four years.

  15. Mary Ellen Avery’s Research Career- Remembrance of Things Past

    Directory of Open Access Journals (Sweden)

    John Steven Torday

    2014-04-01

    Full Text Available Mary Ellen Avery’s research is recognized as a milestone in biomedical research. She had discovered the underlying cause of Hyaline Membrane Disease, surfactant deficiency, fostering ever more vigorous efforts to reduce neonatal mortality in the burgeoning practice of Neonatology. Neonatology is the only clinical discipline that began as an experiment, making it a model for biomedical research. Avery knew that the concerted effort to treat preterm newborns could potentially do more harm than good, violating her oath to Hippocrates, if not held to the highest scientific standards. She remained true to that pledge throughout her career, as recounted in this Review.

  16. Malignant melanoma and Charcot-Marie-Tooth disease: A further case

    Energy Technology Data Exchange (ETDEWEB)

    Manoukian, S.; Briscioli, V.; Lalatta, F. [Instituti Clinici di Perfezionamento, Milan (Italy)

    1997-01-20

    In a previous issue of this journal, Greene et al. described 2 patients with Charcot-Marie-Tooth (CMT) disease who later developed cutaneous malignant melanoma. Although the development of the two diseases in the same patient may have occurred by chance, the authors raised the possibility of a shared neural crest defect or a genetic linkage. Among the patients reported by Greene et al., one had a dominant form of CMT. The patient`s mother and brother were similarly affected. A paternal aunt died of melanoma. The second patient had a neuronal type of CMT. His brother showed the same disease, but the parents were not examined. 7 refs.

  17. Hereditaer motorisk sensorisk neuropati (Charcot-Marie-Tooths sygdom). Molekyloergenetiske aspekter

    DEFF Research Database (Denmark)

    Hertz, M J; Børglum, Anders; Brandt, C A

    1995-01-01

    Hereditary motor and sensory neuropathy (HMSN) comprises a heterogenous group of peripheral neuropathies which are classified on the basis of symptoms, mode of inheritance and electrophysiological and neuropathological investigations. HMSN type I, or Charcot-Marie-Tooth disease (CMT) type 1......-Sottas disease, is a hypertrophic neuropathy with markedly reduced nerve conduction velocity. HMSN type I is genetically heterogenous with at least four autosomal loci and at least two X-linked loci. The most frequent form, HMSN type Ia, is associated with a specific duplication on chromosome 17, which can...

  18. Charcot-Marie-Tooth disease: The development of a diagnostic platform using next generation sequencing

    DEFF Research Database (Denmark)

    Christensen, Rikke; Væth, Signe; Thorsen, Kasper

    Background: Charcot-Marie-Tooth Disease (CMT) is one of the most common inherited neurological diseases. Today, more than 70 CMT related genes are known to cause inherited neuropathy. The diagnostic strategy in most laboratories is based on Sanger-sequencing of few genes. In our patient cohort...... previously analyzed using Sanger sequencing without identification of a disease causing mutation. Materials and Methods: Libraries for 200 patient samples obtained for CMT diagnostics were prepared using Illumina Truseq and target enrichment using SeqCap EZ Choise Library (Nimblegen). The libraries were...

  19. Joint sparing correction of cavovarus feet in Charcot-Marie-Tooth disease: what are the limits?

    Science.gov (United States)

    Barton, Tristan; Winson, Ian

    2013-12-01

    Charcot-Marie-Tooth disease is an inherited neuropathy that results in lower limb muscle imbalance and a resultant cavovarus deformity of the foot. With recognized poor outcomes of triple arthrodeses in the young patient, joint sparing surgery is preferred, which takes the form of osteotomies, soft-tissue releases, and tendon transfers to achieve a plantigrade and balanced foot. Due to the variability in muscle involvement and the presence of both mobile and fixed deformities, surgery must be individualized to each patient. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

  20. Atypical presentation of Charcot-Marie-Tooth disease 1A: A case report.

    Science.gov (United States)

    Kulkarni, Shilpa D; Sayed, Rafat; Garg, Meenal; Patil, Varsha A

    2015-11-01

    Charcot-Marie-Tooth (CMT) 1A is the most common form of CMT disease and is characterized by duplication of Peripheral myelin protein 22 (PMP22) gene. We report a boy with genetically confirmed CMT1A disease having clinical involvement of hypoglossal and glossopharyngeal nerves, as well as asymmetrical and primarily upper limb involvement. These atypical features widen the clinical spectrum of CMT1A, leading to interesting observations about PMP22 gene related disorders and varied clinical expression of similar genetic mutations. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Intermediate Charcot-Marie-Tooth disease: an electrophysiological reappraisal and systematic review.

    Science.gov (United States)

    Berciano, José; García, Antonio; Gallardo, Elena; Peeters, Kristien; Pelayo-Negro, Ana L; Álvarez-Paradelo, Silvia; Gazulla, José; Martínez-Tames, Miriam; Infante, Jon; Jordanova, Albena

    2017-08-01

    Charcot-Marie-Tooth disease (CMT) is the most frequent form of inherited neuropathy with great variety of phenotypes, inheritance patterns, and causative genes. According to median motor nerve conduction velocity (MNCV), CMT is divided into demyelinating (CMT1) with MNCV below 38 m/s, axonal (CMT2) with MNCV above 38 m/s, and intermediate CMT with MNCV between 25 and 45 m/s. In each category, transmission may be autosomal dominant, autosomal recessive, or X-linked. The nosology of intermediate CMT is controversial because of concerns about electrophysiological delimitation. A systematic computer-based literature search was conducted on PubMed, using the following MeSH: (1) intermediate Charcot-Marie-Tooth; (2) X-linked intermediate Charcot-Marie-Tooth; and (3) X-linked Charcot-Marie-Tooth and electrophysiology. We retrieved 225 articles reporting X-linked CMT or intermediate CMT with electrophysiological information. After eligibility, 156 papers were used for this review. In assessing median MNCV, compound muscle action potential (CMAP) amplitudes were taken into account. In cases with attenuated CMAP and wherever possible, proximal median MNCV was used for accurate definition of conduction slowing in the intermediate range. In the vast majority of males with X-linked CMT associated with GJB1 mutation (CMTX1), median MNCV was intermediate. CMT associated with DRP2 mutation is another well-documented X-linked intermediate disorder. Autosomal dominant intermediate CMT (DI-CMT) encompasses 11 different types; six of them with assigned phenotype MIM number and the remaining five being unnumbered. Based on available electrophysiological information, we wonder if DI-CMTA should be reclassified within CMT2. Autosomal recessive intermediate CMT (RI-CMT) covers four numbered MIM phenotypes though, in accordance with reported electrophysiology, two of them (RI-CMTB and RI-CMTD) should probably be reclassified within AR-CMT2. We conclude that intermediate CMT is a complex

  2. Ameerika hävitajad osalesid Ämari õppehäires

    Index Scriptorium Estoniae

    2014-01-01

    Eile maandusid esimest kor­da Ämari kaitseväe lennubaa­sis Ameerika Ühendriikide õhu­väe hävitajad F-15C. Korraldati ka õppehäire, kus hävitajate piloo­did pidid häire peale lennuki­tesse sööstma ja nendega õhku tõusma. Eesti õhuväe õppereaktiivlennukid L-39 etendasid tund­matute õhusõidukite rolli. Need tuli meie õhuruumis üles otsida ja visuaalselt identifitseerida

  3. Low-sampling-rate M-ary multiple access UWB communications in multipath channels

    KAUST Repository

    Alkhodary, Mohammad T.

    2015-08-31

    The desirable characteristics of ultra-wideband (UWB) technology are challenged by formidable sampling frequency, performance degradation in the presence of multi-user interference, and complexity of the receiver due to the channel estimation process. In this paper, a low-rate-sampling technique is used to implement M-ary multiple access UWB communications, in both the detection and channel estimation stages. A novel approach is used for multiple-access-interference (MAI) cancelation for the purpose of channel estimation. Results show reasonable performance of the proposed receiver for different number of users operating many times below Nyquist rate.

  4. Ciencia e industria en el desarrollo de la radiactividad: el caso de Marie Curie

    OpenAIRE

    Roqué, Xavier

    1997-01-01

    Not available.Se argumenta que Marie Curie desarrolló sus investigaciones en radiactividad en estrecha relación con la industria de los radioelementos. Esta relación incluyó desde el desarrollo de procedimientos de extracción para diversas sustancias radiactivas, hasta la promoción de su propio laboratorio industrial. La actividad industrial de Curie se aviene mal con su imagen heroica de científica pura, sacrificada y carente de medios, imagen que, paradójicamente, se retrotrae a las campaña...

  5. Sport activity in Charcot-Marie-Tooth disease: A case study of a Paralympic swimmer.

    Science.gov (United States)

    Vita, Giuseppe; La Foresta, Stefania; Russo, Massimo; Vita, Gian Luca; Messina, Sonia; Lunetta, Christian; Mazzeo, Anna

    2016-09-01

    This study reports the positive physical, emotional and psychosocial changes induced by sport activity in a Paralympic swimmer with Charcot-Marie-Tooth (CMT) type 4A. When we compared evaluations before initiating sport activity with those after five years of competitive activity, we found: i) increased proximal muscles strength of upper limbs; ii) augmented ability to propel wheelchair independently; iii) improved quality of life; iv) reduced trait anxiety and striking improvement of depression; v) enhanced self-esteem. Longitudinal studies in large cohorts to evaluate the positive effects of sport activity are needed to support provision of evidence-based advice to patients and families.

  6. The Analysis of Mary Barton from the Perspective of Spiritual Ecology

    Institute of Scientific and Technical Information of China (English)

    QI Hong-yan

    2016-01-01

    Mary Barton is Elizabeth Gaskell’s first novel, published in 1848, depicted the fierce conflict between working class and capitalist. This novel reveals the fact that with the development of capitalism, capitalist hold the money worship of consum-er cultural perspective, social spiritual slump and self lost. People enter the wasteland of spiritual life, result the imbalanced of mental spiritual. According to describing the disasters of industrial capitalism to human spiritual ecology that draws attention to imbalanced psychology ecology. And advocate to rethinking life significance.

  7. The intellectual legacy of Mary Neth's work on farm women and rural communities.

    Science.gov (United States)

    Osterud, Grey

    2009-01-01

    Mary Neth's 1995 book, "Preserving the Family Farm: Women, Community, and the Foundations of Agribusiness in the Midwest, 1900-1940," made a major contribution to the analysis of the connections between gender and the political economy that shaped farm women's lives and fueled farmers' resistance to the transformation of rural life wrought by agribusiness. Focusing on the processes of negotiation between women and men in farming families and rural communities, Neth illuminated the relationship between women's work and their power. Tracing the dense networks that connected farm families, she also showed how cooperation in work generated and sustained radical farm movements.

  8. Mariátegui, el escritor vanguardista contemporáneo

    Directory of Open Access Journals (Sweden)

    Álvaro Campuzano Arteta

    2005-10-01

    Full Text Available Este ensayo rememora el encuentro ocurrido a inicios del siglo XX entre la literatura vanguardista y el socialismo. Recorriendo un camino que va de los comentarios de José Carlos Mariátegui sobre el cine de Charlie Chaplin, a la exploración de la narrativa vanguardista de Martín Adán, la reflexión aquí propuesta se funda en el pensamiento de Walter Benjamin. Para la elaboración de este trabajo se han desarrollado algunas de las secciones de una tesis de maestría escrita para el Dartmouth College.

  9. A Vindication of the Rights of Woman—An Overview of the Life and Work of England's Early Feminist Mary Wollstonecraft

    Institute of Scientific and Technical Information of China (English)

    李欢欢

    2015-01-01

    Mary Wollstonecraft is an eminent social philosopher and outstanding pioneering advocate of women's rights in Brit-ish history.This paper gives a detailed introduction of Mary Wollstonecraft's life,introduces her most important work A Vindica-tion of the Rights of Woman,and discusses her ideas on education.

  10. Report on the Status of the Cheat Mountain Salamander in the Cabin Mountain Area of West Virginia 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This outlines the results of field surveys that were conducted for the Cheat Mountain salamander on the Kelley property on three mountains in the Cabin Mountain area...

  11. 27 CFR 9.213 - Snipes Mountain.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Snipes Mountain. 9.213... Snipes Mountain. (a) Name. The name of the viticultural area described in this section is “Snipes Mountain”. For purposes of part 4 of this chapter, “Snipes Mountain” is a term of viticultural...

  12. Rocky Mountain spotted fever in children.

    Science.gov (United States)

    Woods, Charles R

    2013-04-01

    Rocky Mountain spotted fever is typically undifferentiated from many other infections in the first few days of illness. Treatment should not be delayed pending confirmation of infection when Rocky Mountain spotted fever is suspected. Doxycycline is the drug of choice even for infants and children less than 8 years old.

  13. 36 CFR 13.910 - Mountain climbing.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Mountain climbing. 13.910 Section 13.910 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... Provisions § 13.910 Mountain climbing. (a) Climbing Mount McKinley or Mount Foraker without a permit...

  14. Summiteers--Moving Mountains with Bereaved Boys

    Science.gov (United States)

    Renner, Hans-Georg

    2011-01-01

    Summiteers are people who rush to the top. There is a mountain summit and a metaphorical summit inside us which we can climb. In the area of mountain summits, Reinhold Messner is surely the best known and most successful summiteer. He climbed, among other things, the highest peak on earth without supplemental oxygen. In the language of the country…

  15. 27 CFR 9.205 - Chehalem Mountains.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Chehalem Mountains. 9.205... Chehalem Mountains. (a) Name. The name of the viticultural area described in this section is “Chehalem Mountains”. For purposes of part 4 of this chapter, “Chehalem Mountains” is a term of...

  16. The mountain vegetation of South Peru

    NARCIS (Netherlands)

    Montesinos-Tubée, D.B.

    2016-01-01

    THE MOUNTAIN VEGETATION OF SOUTH PERU: SYNTAXONOMY, ECOLOGY, PHYTOGEOGRAPHY AND CONSERVATION This thesis presents an overview and revision of plant communities from xerophytic and mountain landscapes in the dry Andes of South Peru. The revision is based on comparison of the collecte

  17. Can wolves help save Japan's mountain forests?

    Science.gov (United States)

    Barber-meyer, Shannon

    2017-01-01

    Japan’s wolves were extinct by 1905. Today Japan's mountain forests are being killed by overabundant sika deer and wild boars. Since the early 1990s, the Japan Wolf Association has proposed wolf reintroduction to Japan to restore rural ecology and to return a culturally important animal. In this article I discuss whether the return of wolves could help save Japan's mountain forests.

  18. A Report from Great Smoky Mountain

    Institute of Scientific and Technical Information of China (English)

    宋瑾

    2008-01-01

    This is a report from Great Smoky Mountain. From this report, I will tell you a story about me and my team. After ten years of hardworking, we made some achievements in Branson, Missouri in America, and then we turned to Great Smoky Mountain for another business. To my group and me, itis like a legend.

  19. The Bauhaus and Black Mountain College

    Science.gov (United States)

    Ellert, JoAnn C.

    1972-01-01

    In view of the sixteen-year tenure (1933-1949) at Black Mountain College of Josef Albers, a former Bauhaus Master, and his wife, Anni, a Bauhaus graduate and teacher, exploration of the influence of the Bauhaus on this small, progressive, art-centered college in the mountains of North Carolina is warrented. (Author)

  20. The mountain vegetation of South Peru

    NARCIS (Netherlands)

    Montesinos-Tubée, D.B.

    2016-01-01

    THE MOUNTAIN VEGETATION OF SOUTH PERU: SYNTAXONOMY, ECOLOGY, PHYTOGEOGRAPHY AND CONSERVATION This thesis presents an overview and revision of plant communities from xerophytic and mountain landscapes in the dry Andes of South Peru. The revision is based on comparison of the