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Sample records for force production capacity

  1. Unknown loads affect force production capacity in early phases of bench press throws.

    Hernández Davó, J L; Sabido Solana, R; Sarabia Marínm, J M; Sánchez Martos, Á; Moya Ramón, M

    2015-10-01

    Explosive strength training aims to improve force generation in early phases of movement due to its importance in sport performance. The present study examined the influence of lack of knowledge about the load lifted in explosive parameters during bench press throws. Thirteen healthy young men (22.8±2.0 years) participated in the study. Participants performed bench press throws with three different loads (30, 50 and 70% of 1 repetition maximum) in two different conditions (known and unknown loads). In unknown condition, loads were changed within sets in each repetition and participants did not know the load, whereas in known condition the load did not change within sets and participants had knowledge about the load lifted. Results of repeated-measures ANOVA revealed that unknown conditions involves higher power in the first 30, 50, 100 and 150 ms with the three loads, higher values of ratio of force development in those first instants, and differences in time to reach maximal rate of force development with 50 and 70% of 1 repetition maximum. This study showed that unknown conditions elicit higher values of explosive parameters in early phases of bench press throws, thereby this kind of methodology could be considered in explosive strength training.

  2. An in vitro correlation of mechanical forces and metastatic capacity

    Indra, Indrajyoti; Undyala, Vishnu; Kandow, Casey; Thirumurthi, Umadevi; Beningo, Karen A; Dembo, Micah

    2011-01-01

    Mechanical forces have a major influence on cell migration and are predicted to significantly impact cancer metastasis, yet this idea is currently poorly defined. In this study we have asked if changes in traction stress and migratory properties correlate with the metastatic progression of tumor cells. For this purpose, four murine breast cancer cell lines derived from the same primary tumor, but possessing increasing metastatic capacity, were tested for adhesion strength, traction stress, focal adhesion organization and for differential migration rates in two-dimensional and three-dimensional environments. Using traction force microscopy (TFM), we were surprised to find an inverse relationship between traction stress and metastatic capacity, such that force production decreased as the metastatic capacity increased. Consistent with this observation, adhesion strength exhibited an identical profile to the traction data. A count of adhesions indicated a general reduction in the number as metastatic capacity increased but no difference in the maturation as determined by the ratio of nascent to mature adhesions. These changes correlated well with a reduction in active beta-1 integrin with increasing metastatic ability. Finally, in two dimensions, wound healing, migration and persistence were relatively low in the entire panel, maintaining a downward trend with increasing metastatic capacity. Why metastatic cells would migrate so poorly prompted us to ask if the loss of adhesive parameters in the most metastatic cells indicated a switch to a less adhesive mode of migration that would only be detected in a three-dimensional environment. Indeed, in three-dimensional migration assays, the most metastatic cells now showed the greatest linear speed. We conclude that traction stress, adhesion strength and rate of migration do indeed change as tumor cells progress in metastatic capacity and do so in a dimension-sensitive manner

  3. The product of capacities and belief functions

    Hendon, Ebbe; Whitta-Jacobsen, Hans Jørgen; Sloth, Birgitte

    1996-01-01

    Capacities (monotone, non-additive set functions) have been suggested to describe situations of uncertainty. We examine the question of how to define the product of two independent capacities. In particular, for the product of two belief functions (totally monotone capacities), there is a unique...... minimal product belief function. This is characterized in several ways...

  4. The product of capacities and belief functions

    Hendon, Ebbe; Jacobsen, Hans Jørgen; Sloth, Birgitte

    1996-01-01

    Capacities (monotone, non-additive set functions) have been suggested to describe situations of uncertainty. We examine the question of how to define the product of two independent capacities. In particular, for the product of two belief functions (totally monotone capacities), there is a unique...... minimal product belief function. This is characterized in several ways....

  5. The Driving Forces of Subsidiary Absorptive Capacity

    Schleimer, Stephanie C.; Pedersen, Torben

    2013-01-01

    The study investigates how a multinational corporation (MNC) can promote the absorptive capacity of its subsidiaries. The focus is on what drives the MNC subsidiary's ability to absorb marketing strategies that are initiated by the MNC parent, as well as how the subsidiary enacts on this absorptive...... as a purposeful response to this dual embeddedness. An analysis of marketing strategy absorptions undertaken by 213 subsidiaries reveals that MNCs can assist their subsidiaries to compete in competitive and dynamic focal markets by forming specific organizational mechanisms that are conducive to the development...

  6. Measuring excess capital capacity in agricultural production

    Zhengfei, G.; Kumbhakar, S.C.; Myers, R.J.; Oude Lansink, A.G.J.M.

    2009-01-01

    We introduce the concept "excess capital capacity" and employ a stochastic input requirement frontier to measure excess capital capacity in agricultural production. We also propose a two-step estimation method that allows endogenous regressors in stochastic frontier models. The first step uses

  7. Commandants' Managerial Capacity and Workers Productivity in ...

    The purpose of this study is to evaluate the commandant's managerial capacity as if relates to workers productivity with a view to determining whether their calling to the education terrain has been justified and to correct certain areas in need of improvement in the Nigeria Police Education set up. In doing this, the study took ...

  8. Pdvsa plans to hike productive capacity

    Anon.

    1992-01-01

    This paper reports that Venezuela's state oil company plans to jump its productive capacity by 117,000 b/d to 2.92 million b/d this year. Petroleos de Venezuela also projects sizable increases for oil and gas reserves and plans record spending in 1992. Meantime, Pdvsa is sounding a warning again about the Venezuelan government's excessive tax take amid debate within the company about spending priorities

  9. Measures for Increasing of Company’s Production Capacity

    Ernesta Žikevičiūtė; Irena Zabielavičienė

    2012-01-01

    Production capacity improvements are poorly explored areas of economic literature and the existing methods are difficult to apply. For this reason, the organization has only a superficial analysis of capacity, but after all this time, each production company had to improve the production capacity for the market economy and the most economical use of production factors.This article explores the company’s production capacity for better use of tools. It also presents the capacity of their conce...

  10. Attentional Focusing Instructions and Force Production

    David C Marchant

    2011-01-01

    Full Text Available Research progress assessing the role of attentional focusing instructions on skill acquisition and performance has lead researchers to apply this approach to force production tasks. Initial converging evidence indicates that force production tasks are sensitive to verbal instruction; externally focused instructions (onto movement outcomes, or onto the object force is being exerted against are shown to be more beneficial than internally focused instructions (focusing attention onto the movements being executed. These benefits are observed for maximal and accurate force production, as well as the maintenance of force production in prolonged tasks. A range of mechanisms are identified supporting the proposal that an external focus promotes movement efficiency in line with energy and effort conservation. Future research is required to assess how this developing body of work interacts with the broader understanding of psychological and physiological factors implicated in the effective production, maintenance and limitation of maximal or sub-maximal forces.

  11. Measures for Increasing of Company’s Production Capacity

    Ernesta Žikevičiūtė

    2012-07-01

    Full Text Available Production capacity improvements are poorly explored areas of economic literature and the existing methods are difficult to apply. For this reason, the organization has only a superficial analysis of capacity, but after all this time, each production company had to improve the production capacity for the market economy and the most economical use of production factors.This article explores the company’s production capacity for better use of tools. It also presents the capacity of their concept, establishment, evaluates the factors leading to their production capacity, for developing efficiency measures and model presentation.Article in Lithuanian

  12. Methods and measures of enhancing production capacity of uranium mines

    Ni Yuhui

    2013-01-01

    Limited by resource conditions and mining conditions, the production capacity of uranium mines is generally small. The main factors to affect the production capacity determination of uranium mines are analyzed, the ways and measures to enhance the production capacity of uranium mines are explored from the innovations of technology and management mode. (author)

  13. Production of isometric forces during sustained acceleration.

    Sand, D P; Girgenrath, M; Bock, O; Pongratz, H

    2003-06-01

    The operation of high-performance aircraft requires pilots to apply finely graded forces on controls. Since they are often exposed to high levels of acceleration in flight, we investigated to what extent this ability is degraded in such an environment. Twelve healthy non-pilot volunteers were seated in the gondola of a centrifuge and their performance was tested at normal gravity (1 G) and while exposed to sustained forces of 1.5 G and 3 G oriented from head to foot (+Gz). Using an isometric joystick, they attempted to produce force vectors with specific lengths and directions commanded in random order by a visual display. Acceleration had substantial effects on the magnitude of produced force. Compared with 1 G, maximum produced force was about 2 N higher at 1.5 G and about 10 N higher at 3 G. The size of this effect was constant across the different magnitudes, but varied with the direction of the prescribed force. Acceleration degrades control of force production. This finding may indicate that the motor system misinterprets the unusual gravitoinertial environment and/or that proprioceptive feedback is degraded due to increased muscle tone. The production of excessive isometric force could affect the safe operation of high-performance aircraft.

  14. Capacity and production planning with carbon emission constraints

    Govindan, Kannan; Song, Shuang; Xu, Lei

    2017-01-01

    This paper builds a two-stage, stochastic model to study capacity expansion problem in logistics under cap-and-trade and carbon tax regulations. The optimal capacity expansion and production decisions are obtained, and the effects of carbon emission regulations on capacity expansion are studied....... Through analytical study and a real case numerical analysis, we find that the carbon tax exhibits different impacts on optimal capacity expansion decisions in low tax rate and high tax rate, and the volatility of capacity investment cost has a larger impact on optimal capacity expansion than...... that of production cost....

  15. Charm production and the confining force field

    Andersson, B.; Bengtsson, H.-U.; Gustafson, G.

    1983-03-01

    We show that charm production at SPS energies can be understood simply from O(α 2 sub (s)) QCD processes when combined with fragmentation of the colour fields stretched by the final state partons. The tension of the confining force field responsible for particle production is found to pull the charmed particles away from the reaction centre, giving rise to a harder x sub (F)-spectrum than would be expected from the bare QCD matrix elements. (Authors)

  16. Level of hamstrings damage depending on force-generating capacity and creatine kinase activity

    Carmona, Gerard; Alomar, Xavier; Mendiguchia, Jurdan; Serrano, David; Padullés, Josep Maria; Nescolarde Selva, Lexa Digna; Rodas Font, Gil; Cusso Calabuig, Roser; Guerrero, M.; Idoate, F.; Balius, Ramon; Cadefau, Joan

    2014-01-01

    The aim of the present study was to categorize the eccentric exercise-induced hamstrings damage by using easy measurable markers such as force-generating capacity and serum creatine kinase activity Peer Reviewed

  17. The relationship between obesity and forced vital capacity among university students.

    Sun, Xugui; Chen, Xiaohong

    2015-05-01

    We sought to explore the relationship between vital capacity and obesity among university students in China. A cross-sectional study was designed to collect the routine health screening data for university students in 2013. The height, weight and force vital capacity of students were measured, and BMI was calculated with height and weight, so as to estimate the relationship between force vital capacity and obesity. Based on Working Group on Obesity references in China, obesity has a higher force vital capacity in both male and female university students. No correlation was found between vital capacity and BMI. obesity may have effect on pulmonary function among university students, which is a reference for further epidemic study. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  18. Saudi production capacity climbing to 10 million b/d

    Anon.

    1994-01-01

    Saudi Arabia this year is completing its expansion of production capacity and developing recent discoveries to enhance export flexibility. The 3 million b/d capacity expansion to 10 million b/d, announced in 1989, is on target for completion by year end 1994. Most of the effort involves restoration of mothballed production equipment and installation of several gas-oil separation plants (GOSPs) in existing fields. But Saudi Arabian Oil Co. (Saudi Aramco) also this year will start up production of extra-light oil from a new field in the central part of the kingdom. Start-up of Hawtah area production demonstrates success of an oil search Aramco began after receiving exclusive exploration rights to nearly all of Saudi Arabia's prospective area in 1986. From new fields and traditional producing areas, therefore, Saudi Arabia has the potential to expand production capacity beyond 10 million b/d. The paper describes the development of the extra capacity

  19. The new science of sales force productivity.

    Ledingham, Dianne; Kovac, Mark; Simon, Heidi Locke

    2006-09-01

    For years, sales managers at many companies have relied on top performers and sheer numbers of sales reps to stay competitive. But while they may have squeaked by on this wing-and-a-prayer technique, their sales teams haven't thrived the way they once did. Today's most successful sales leaders are taking a more scientific approach. Savvy managers are reshaping their tactics in response to changing markets. They are reaching out to new customers in innovative ways. And they are increasing productivity by helping the reps they already have make the most of their skills and resources. Leaders who take a scientific approach to sales force effectiveness have learned to use four levers to boost their reps' productivity in a predictable and manageable way. First, they systematically target their firms' offerings, matching the right products with the right customers. Second, they optimize the automation, tools, and procedures at their disposal, providing reps with the support they need to boost sales.Third, they analyze and manage their reps' performance, measuring both internal processes and results to determine where their teams' strengths and weaknesses are. Fourth, they pay close attention to sales force deployment--how well sales, support, marketing, and delivery resources are matched to customers. These four levers can help sales leaders increase productivity across the board, the authors say, though they have the greatest impact on lower-ranked performers. The overall effect of increasing the average sales per employee can be exponential; it means a company won't have to rely on just a few talented individuals to stay competitive. This is especially important because finding and keeping star salespeople is more difficult than ever. What's more, managers who optimize the sales forces they already have can see returns they never thought possible.

  20. Managing the Newsvendor Modeled Product System with Random Capacity and Capacity-Dependent Price

    Qingying Li

    2015-01-01

    Full Text Available We consider a newsvendor modeled product system, where the firm provides products to the market. The supply capacity of the product is random, so the firm receives either the amount of order quantity or the realized capacity, whichever is smaller. The market price is capacity dependent. We consider two types of production cost structures: the procurement case and the in-house production case. The firm pays for the received quantity in the former case and for the ordered quantity in the latter case. We obtain the optimal order quantities for both cases. Comparing with the traditional newsvendor model, we find that the optimal order quantity in both the procurement case and the in-house production case are no greater than that in the traditional newsvendor model with a fixed selling price. We also find that the optimal order quantity for the procurement case is greater than that for the in-house production case. Numerical study is conducted to investigate the sensitivity of the optimal solution versus the distribution of the random capacity/demand.

  1. GASCAP: Wellhead Gas Productive Capacity Model documentation, June 1993

    1993-01-01

    The Wellhead Gas Productive Capacity Model (GASCAP) has been developed by EIA to provide a historical analysis of the monthly productive capacity of natural gas at the wellhead and a projection of monthly capacity for 2 years into the future. The impact of drilling, oil and gas price assumptions, and demand on gas productive capacity are examined. Both gas-well gas and oil-well gas are included. Oil-well gas productive capacity is estimated separately and then combined with the gas-well gas productive capacity. This documentation report provides a general overview of the GASCAP Model, describes the underlying data base, provides technical descriptions of the component models, diagrams the system and subsystem flow, describes the equations, and provides definitions and sources of all variables used in the system. This documentation report is provided to enable users of EIA projections generated by GASCAP to understand the underlying procedures used and to replicate the models and solutions. This report should be of particular interest to those in the Congress, Federal and State agencies, industry, and the academic community, who are concerned with the future availability of natural gas

  2. The productive cellulase binding capacity of cellulosic substrates.

    Karuna, Nardrapee; Jeoh, Tina

    2017-03-01

    Cellulosic biomass is the most promising feedstock for renewable biofuel production; however, the mechanisms of the heterogeneous cellulose saccharification reaction are still unsolved. As cellulases need to bind isolated molecules of cellulose at the surface of insoluble cellulose fibrils or larger aggregated cellulose structures in order to hydrolyze glycosidic bonds, the "accessibility of cellulose to cellulases" is considered to be a reaction limiting property of cellulose. We have defined the accessibility of cellulose to cellulases as the productive binding capacity of cellulose, that is, the concentration of productive binding sites on cellulose that are accessible for binding and hydrolysis by cellulases. Productive cellulase binding to cellulose results in hydrolysis and can be quantified by measuring hydrolysis rates. In this study, we measured the productive Trichoderma reesei Cel7A (TrCel7A) binding capacity of five cellulosic substrates from different sources and processing histories. Swollen filter paper and bacterial cellulose had higher productive binding capacities of ∼6 µmol/g while filter paper, microcrystalline cellulose, and algal cellulose had lower productive binding capacities of ∼3 µmol/g. Swelling and regenerating filter paper using phosphoric acid increased the initial accessibility of the reducing ends to TrCel7A from 4 to 6 µmol/g. Moreover, this increase in initial productive binding capacity accounted in large part for the difference in the overall digestibility between filter paper and swollen filter paper. We further demonstrated that an understanding of how the productive binding capacity declines over the course of the hydrolysis reaction has the potential to predict overall saccharification time courses. Biotechnol. Bioeng. 2017;114: 533-542. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. CALCULATION OF INITIALS OPTIMAL PRODUCTION CAPACITIES CONSIDERING UNCERTAINTY ELEMENTS

    Hilda Oquendo Ferrer

    2016-04-01

    Full Text Available In diversification, an attractive variant constitutes the projection of ethanol plants due to all the advantages that this represents and a crucial element for this to be effective is the existence of cane as a fundamental raw material for the sugar industry and therefore the derived productions. To project the initials optimal capacity of the plant, uncertainty in the raw material was considered. Mathematical models of capacity in time are obtained, choosing those that best fit, being the linear the simplest for future calculations. The initial capacity the plant should have is determined, also the time at which the first extension and the capacity of the plant should be done, which allows, considering other criteria, to make decisions about what should be the capacity of an ethanol plant in response to the current and future availability of sugar cane. It is presented a general method that can be used considering other tax sugar companies in a province or a region.

  4. It Systems Supporting the Management of Production Capacity

    Milewska, Elżbieta

    2017-03-01

    The paper presents the problem of manufacturing process flexibility in view of a company's material and information flow stream management. The author of the article has described the functions of a production process control system and presented the characteristics of production capacity intensive and extensive reserves. The MRP II/ERP, MES and APS class IT tools supporting the process of production planning, organization and control have also been discussed.

  5. IT SYSTEMS SUPPORTING THE MANAGEMENT OF PRODUCTION CAPACITY

    Elżbieta MILEWSKA

    2017-01-01

    Full Text Available The paper presents the problem of manufacturing process flexibility in view of a company’s material and information flow stream management. The author of the article has described the functions of a production process control system and presented the characteristics of production capacity intensive and extensive reserves. The MRP II/ERP, MES and APS class IT tools supporting the process of production planning, organization and control have also been discussed.

  6. IT SYSTEMS SUPPORTING THE MANAGEMENT OF PRODUCTION CAPACITY

    Elżbieta MILEWSKA

    2017-01-01

    The paper presents the problem of manufacturing process flexibility in view of a company’s material and information flow stream management. The author of the article has described the functions of a production process control system and presented the characteristics of production capacity intensive and extensive reserves. The MRP II/ERP, MES and APS class IT tools supporting the process of production planning, organization and control have also been discussed.

  7. Phytochemical composition and antioxidant capacity of whole wheat products

    Whole wheat contains an array of phytochemicals. We quantified alkylresorcinols (AR), phenolic acids, phytosterols, and tocols in six whole wheat products and characterized their antioxidant capacity and ability to induce quinone reductase activity (QR). Total AR content ranged from 136.8 to 233.9 m...

  8. Expanding OPEC production capacity: some legal and environmental aspects

    Al-Sahlawi, M.A.

    1992-01-01

    There is general consensus that the global demand for oil will increase in the medium-to-long term. It is predicted that much of this additional demand will be for OPEC oil. Therefore, it will become necessary to expand OPEC production capacity to meet this perceived increase. In recent years, many OPEC countries have launched far-reaching and, in some cases, radical plans to expand their production capacity. However, given the various investment and political constraints faced by the 13 OPEC Members, each country differs markedly in its ability to boost production capacity sufficiently to meet self-imposed targets. In this paper, we examine the importance to the oil market of recent oil supply trends and possible future attempts to build OPEC production capacity, focussing in particular on the legal and environmental issues involved. A review is provided of the legal mechanisms currently evolving in OPEC Countries to encourage investment in their oil industries. In addition, we outline the impact of the environmental movement of OPEC's expansion programmes. (author)

  9. Criterion III: Maintenance of rangeland productive capacity [Chapter 4

    G. R. Evans; R. A. Washmgton-Allen; R. D. Child; J. E. Mitchell; B. R. Bobowskl; R. V. Loper; B. H. Allen-Diaz; D. W. Thompson; G. R. Welling; T. B. Reuwsaat

    2010-01-01

    Maintenance of rangeland productive capacity is one of five criteria established by the Sustainable Rangelands Roundtable (SRR) to monitor and assess rangeland sustainable management. Within this criterion, six indicators were developed through the Delphi Process and the expert opinions of academicians, rangeland scientists, rangeland management agency personnel, non-...

  10. Strength and Power Training Effects on Lower Limb Force, Functional Capacity, and Static and Dynamic Balance in Older Female Adults.

    Lopes, Paula Born; Pereira, Gleber; Lodovico, Angélica; Bento, Paulo C B; Rodacki, André L F

    2016-03-03

    It has been proposed that muscle power is more effective to prevent falls than muscle force production capacity, as rapid reactions are required to allow the postural control. This study aimed to compare the effects of strength and power training on lower limb force, functional capacity, and static and dynamic balance in older female adults. Thirty-seven volunteered healthy women had been allocated into the strength-training group (n = 14; 69 ± 7.3 years, 155 ± 5.6 cm, 72 ± 9.7 kg), the power-training group (n = 12; 67 ± 7.4 years, 153 ± 5.5 cm, 67.2 ± 7 kg), and control group (n = 11; 65 ± 3.1 years, 154 ± 5.6 cm, 70.9 ± 3 kg). After 12 weeks of training, the strength-training and power-training groups increased significantly maximum dynamic strength (29% and 27%), isometric strength (26% and 37%), and step total time (13% and 14%, dynamic balance), respectively. However, only the power-training group increased the rate of torque development (55%) and the functional capacity in 30-second chair stand (22%) and in time up and go tests (-10%). Empirically, power training may reduce the risk of injuries due to lower loads compared to strength training, and consequently, the physical effort demand during the training session is lower. Therefore, power training should be recommended as attractive training stimuli to improve lower limb force, functional capacity, and postural control of older female adults.

  11. Embryo developmental capacity of oocytes fertilised by sperm of mouse exposed to forced swimming stress

    Ghasem, S.; Majid, J.; Shiva, R.

    2013-01-01

    Objective: To assess developmental capacity of fertilised oocytes by sperm of mouse exposed to forced swimming stress. Methods: The experimental study was conducted at the Physiology Research Center of Ahvaz Jundishapur University of Medical Sciences, from August 2011 to January 2012. It comprised 20 adult male and 10 female mice. The male mice were randomly divided into two equal groups (n=10): control and experimental. Animals of the experimental group were submitted to forced swimming stress. All male mice were euthanised and the cauda epididymis removed before contents were squeezed out. A pre-incubated capacitated sperm was gently added to the freshly collected ova of the two groups of study. The combined sperm-oocyte suspension was incubated for 4-6 hours under a condition of 5% Carbon dioxide and 37 degree C temperature. The ova were then washed through several changes of medium and finally incubated. Fertilisation was assessed by recording the number of 1-cell embryos 4-6 hours after insemination. The 1-cell embryos were allowed to further develop in vitro for about 120 hours. Development of embryos everyday and during 5 days of culture was observed by using inverted microscope. SPSS 13.0.1 was used for statistical analysis. Results: The percentage of oocytes fertilised was 75:96 (78.12+-4.8%) and 50:10 (49.5+-3.9%) in the control and experimental groups, respectively. The difference was significant (p 0.05) between the two groups in terms of speed and developmental capacity of blastocysts. Conclusions: Fertilisation capacity of male mice affected by forced swimming stress and also the developmental capacity of oocyte fertilised by sperm of mouse exposed to forced swimming stress decreased. (author)

  12. Embryo developmental capacity of oocytes fertilised by sperm of mouse exposed to forced swimming stress.

    Ghasem, Saki; Majid, Jasemi; Shiva, Razi

    2013-07-01

    To assess developmental capacity of fertilised oocytes by sperm of mouse exposed to forced swimming stress. The experimental study was conducted at the Physiology Research Center of Ahvaz Jundishapur University of Medical Sciences, from August 2011 to January 2012. It comprised 20 adult male and 10 female mice. The male mice were randomly divided into two equal groups (n=10): control and experimental. Animals of the experimental group were submitted to forced swimming stress. All male mice were euthanised and the cauda epididymis removed before contents were squeezed out. A pre-incubated capacitated sperm was gently added to the freshly collected ova of the two groups of study. The combined sperm-oocyte suspension was incubated for 4-6 hours under a condition of 5% Carbon dioxide and 37 degreeC temperature. The ova were then washed through several changes of medium and finally incubated. Fertilisation was assessed by recording the number of 1-cell embryos 4-6 hours after insemination. The 1-cell embryos were allowed to further develop in vitro for about 120 hours. Development of embryos everyday and during 5 days of culture was observed by using inverted microscope. SPSS 13.0.1 was used for statistical analysis. The percentage of oocytes fertilised was 75:96 (78.12+/-4.8%) and 50:10 (49.5+/-3.9%) in the control and experimental groups, respectively. The difference was significant (p 0.05) between the two groups in terms of speed and developmental capacity of blastocysts. Fertilisation capacity of male mice affected by forced swimming stress and also the developmental capacity of oocyte fertilised by sperm of mouse exposed to forced swimming stress decreased.

  13. Lactate and force production in skeletal muscle

    Kristensen, Michael; Albertsen, Janni; Rentsch, Maria

    2005-01-01

    Lactic acid accumulation is generally believed to be involved in muscle fatigue. However, one study reported that in rat soleus muscle (in vitro), with force depressed by high external K+ concentrations a subsequent incubation with lactic acid restores force and thereby protects against fatigue...

  14. Factors Affecting Productivity in the United States Naval Construction Force

    Morton, Darren

    1997-01-01

    By using a craftsman questionnaire, this thesis identifies and ranks the most important factors impairing Petty Officer productivity and morale in the United States Naval Construction Force (Seabees...

  15. Nigeria's oil production and the need for increased producing capacity

    Okoroji, C. E. I.

    1998-01-01

    After 40 years of commercial oil production, Nigeria's crude oil production is moving through difficult times. This transition period has been made more difficult because of recurring international economic recession, lack-luster crude prices, and slow oil demand growth and Government funding problems etc. Crude oil remains the most important export revenue earner in Nigeria, and more efforts are required to encourage higher output levels to support more foreign exchange generation. Nigeria's crude oil production at present stands at 2.2 million barrels per day (mbpd). This study, covers the period 1998-2005, during which oil production is forecast to grow to about 2.85 mbpd while potential for new discoveries could raise production to more than 3.0 mbpd. These projected rates could depend to a large extent on the rate and size of new discoveries. However, Nigeria's crude oil potential is being constrained by both lack of infrastructure and inadequate investment. The massive investment needed to raise the country's productive capacity will require foreign capital, yet the current fiscal environment leaves much to be desired. The purpose of this paper is to present a review of Nigeria's past, present and future oil production. To meet the projected production capacity very early in the next millennium, current estimates put the overall potential investment needed for an accelerated capacity-expansion drive in order to ensure that there is adequate cushion of crude potential at $19.7 billion during the next seven years. Furthermore, not more than $12.0 billion of this requirement can be generated from Nigeria's government cash flow

  16. On the optimal production capacity for influenza vaccine.

    Forslid, Rikard; Herzing, Mathias

    2015-06-01

    This paper analyzes the profit maximizing capacity choice of a monopolistic vaccine producer facing the uncertain event of a pandemic in a homogenous population of forward-looking individuals. For any capacity level, the monopolist solves the intertemporal price discrimination problem within the dynamic setting generated by the standard mathematical epidemiological model of infectious diseases. Even though consumers are assumed to be identical, the monopolist will be able to exploit the ex post heterogeneity between infected and susceptible individuals by raising the price of vaccine in response to the increasing hazard rate. The monopolist thus bases its investment decision on the expected profits from the optimal price path given the infection dynamics. It is shown that the monopolist will always choose to invest in a lower production capacity than the social planner. Through numerical simulation, it is demonstrated how the loss to society of having a monopoly producer decreases with the speed of infection transmission. Moreover, it is illustrated how the monopolist's optimal vaccination rate increases as its discount rate rises for cost parameters based on Swedish data. However, the effect of the firm discount rate on its investment decision is sensitive to assumptions regarding the cost of production capacity. Copyright © 2014 John Wiley & Sons, Ltd.

  17. Alluvial Diamond Resource Potential and Production Capacity Assessment of Ghana

    Chirico, Peter G.; Malpeli, Katherine C.; Anum, Solomon; Phillips, Emily C.

    2010-01-01

    In May of 2000, a meeting was convened in Kimberley, South Africa, and attended by representatives of the diamond industry and leaders of African governments to develop a certification process intended to assure that rough, exported diamonds were free of conflictual concerns. This meeting was supported later in 2000 by the United Nations in a resolution adopted by the General Assembly. By 2002, the Kimberley Process Certification Scheme (KPCS) was ratified and signed by both diamond-producing and diamond-importing countries. Over 70 countries were included as members at the end of 2007. To prevent trade in 'conflict' diamonds while protecting legitimate trade, the KPCS requires that each country set up an internal system of controls to prevent conflict diamonds from entering any imported or exported shipments of rough diamonds. Every diamond or diamond shipment must be accompanied by a Kimberley Process (KP) certificate and be contained in tamper-proof packaging. The objective of this study was to assess the alluvial diamond resource endowment and current production capacity of the alluvial diamond-mining sector in Ghana. A modified volume and grade methodology was used to estimate the remaining diamond reserves within the Birim and Bonsa diamond fields. The production capacity of the sector was estimated using a formulaic expression of the number of workers reported in the sector, their productivity, and the average grade of deposits mined. This study estimates that there are approximately 91,600,000 carats of alluvial diamonds remaining in both the Birim and Bonsa diamond fields: 89,000,000 carats in the Birim and 2,600,000 carats in the Bonsa. Production capacity is calculated to be 765,000 carats per year, based on the formula used and available data on the number of workers and worker productivity. Annual production is highly dependent on the international diamond market and prices, the numbers of seasonal workers actively mining in the sector, and

  18. Increased Capacity for Work and Productivity After Breast Reduction.

    Cabral, Isaias Vieira; Garcia, Edgard da Silva; Sobrinho, Rebecca Neponucena; Pinto, Natália Lana Larcher; Juliano, Yara; Veiga-Filho, Joel; Ferreira, Lydia Masako; Veiga, Daniela Francescato

    2017-01-01

    Breast hypertrophy is a prevalent condition among women worldwide, which can affect different aspects of their quality of life. The physical and emotional impact of breast hypertrophy may harm daily activities, including work. To assess the impact of reduction mammaplasty on the ability to work and productivity of women with breast hypertrophy. A total of 60 patients with breast hypertrophy, already scheduled for breast reduction, aged 18 to 60 years and who had formal or autonomous employment were prospectively enrolled. The Brazilian versions of two validated tools, Work Productivity and Activity Impairment - General Health (WPAI-GH) and Work Limitations Questionnaire (WLQ) were self-administered at the preoperative evaluation and six months following surgery. The median age was 33 years, median body mass index was 24 kg/m 2 , and the median total weight of resected breast tissue was 617.5 g. According to the Brazilian classification of occupation, most patients (53%) had technical, scientific, artistic and similar occupations. There was a significant improvement in work capacity and productivity six months after the reduction mammaplasty, denoted by a decrease in presenteeism, absenteeism, and WLQ Productivity Loss Score (Wilcoxon analysis of variance: P work capacity and productivity of Brazilian women with breast hypertrophy. LEVEL OF EVIDENCE 4. © 2016 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  19. Effects of oncoming target velocities on rapid force production and accuracy of force production intensity and timing.

    Ohta, Yoichi

    2017-12-01

    The present study aimed to clarify the effects of oncoming target velocities on the ability of rapid force production and accuracy and variability of simultaneous control of both force production intensity and timing. Twenty male participants (age: 21.0 ± 1.4 years) performed rapid gripping with a handgrip dynamometer to coincide with the arrival of an oncoming target by using a horizontal electronic trackway. The oncoming target velocities were 4, 8, and 12 m · s -1 , which were randomly produced. The grip force required was 30% of the maximal voluntary contraction. Although the peak force (Pf) and rate of force development (RFD) increased with increasing target velocity, the value of the RFD to Pf ratio was constant across the 3 target velocities. The accuracy of both force production intensity and timing decreased at higher target velocities. Moreover, the intrapersonal variability in temporal parameters was lower in the fast target velocity condition, but constant variability in 3 target velocities was observed in force intensity parameters. These results suggest that oncoming target velocity does not intrinsically affect the ability for rapid force production. However, the oncoming target velocity affects accuracy and variability of force production intensity and timing during rapid force production.

  20. Absorptive capacity, technological innovation, and product life cycle: a system dynamics model.

    Zou, Bo; Guo, Feng; Guo, Jinyu

    2016-01-01

    While past research has recognized the importance of the dynamic nature of absorptive capacity, there is limited knowledge on how to generate a fair and comprehensive analytical framework. Based on interviews with 24 Chinese firms, this study develops a system-dynamics model that incorporates an important feedback loop among absorptive capacity, technological innovation, and product life cycle (PLC). The simulation results reveal that (1) PLC affects the dynamic process of absorptive capacity; (2) the absorptive capacity of a firm peaks in the growth stage of PLC, and (3) the market demand at different PLC stages is the main driving force in firms' technological innovations. This study also explores a sensitivity simulation using the variables of (1) time spent in founding an external knowledge network, (2) research and development period, and (3) knowledge diversity. The sensitivity simulation results show that the changes of these three variables have a greater impact on absorptive capacity and technological innovation during growth and maturity stages than in the introduction and declining stages of PLC. We provide suggestions on how firms can adjust management policies to improve their absorptive capacity and technological innovation performance during different PLC stages.

  1. Morphological characteristics and egg production of forced-moult ...

    The forced-moult groups T2 and T3 stopped egg production by 6 days of moult induction and resumed egg production by day 25. T2 and T3 attained a peak egg production of 71% by the second month following resumption of lay. On the other hand, in the T1 egg production progressively decreased with age.

  2. Comparison of bee products based on assays of antioxidant capacities

    Mishima Satoshi

    2009-02-01

    Full Text Available Abstract Background Bee products (including propolis, royal jelly, and bee pollen are popular, traditional health foods. We compared antioxidant effects among water and ethanol extracts of Brazilian green propolis (WEP or EEP, its main constituents, water-soluble royal jelly (RJ, and an ethanol extract of bee pollen. Methods The hydrogen peroxide (H2O2-, superoxide anion (O2·--, and hydroxyl radical (HO·- scavenging capacities of bee products were measured using antioxidant capacity assays that employed the reactive oxygen species (ROS-sensitive probe 5-(and-6-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester (CM-H2DCFDA or aminophenyl fluorescein (APF. Results The rank order of antioxidant potencies was as follows: WEP > EEP > pollen, but neither RJ nor 10-hydroxy-2-decenoic acid (10-HDA had any effects. Concerning the main constituents of WEP, the rank order of antioxidant effects was: caffeic acid > artepillin C > drupanin, but neither baccharin nor coumaric acid had any effects. The scavenging effects of caffeic acid were as powerful as those of trolox, but stronger than those of N-acetyl cysteine (NAC or vitamin C. Conclusion On the basis of the present assays, propolis is the most powerful antioxidant of all the bee product examined, and its effect may be partly due to the various caffeic acids it contains. Pollen, too, exhibited strong antioxidant effects.

  3. Comparison of bee products based on assays of antioxidant capacities.

    Nakajima, Yoshimi; Tsuruma, Kazuhiro; Shimazawa, Masamitsu; Mishima, Satoshi; Hara, Hideaki

    2009-02-26

    Bee products (including propolis, royal jelly, and bee pollen) are popular, traditional health foods. We compared antioxidant effects among water and ethanol extracts of Brazilian green propolis (WEP or EEP), its main constituents, water-soluble royal jelly (RJ), and an ethanol extract of bee pollen. The hydrogen peroxide (H2O2)-, superoxide anion (O2.-)-, and hydroxyl radical (HO.)- scavenging capacities of bee products were measured using antioxidant capacity assays that employed the reactive oxygen species (ROS)-sensitive probe 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester (CM-H2DCFDA) or aminophenyl fluorescein (APF). The rank order of antioxidant potencies was as follows: WEP > EEP > pollen, but neither RJ nor 10-hydroxy-2-decenoic acid (10-HDA) had any effects. Concerning the main constituents of WEP, the rank order of antioxidant effects was: caffeic acid > artepillin C > drupanin, but neither baccharin nor coumaric acid had any effects. The scavenging effects of caffeic acid were as powerful as those of trolox, but stronger than those of N-acetyl cysteine (NAC) or vitamin C. On the basis of the present assays, propolis is the most powerful antioxidant of all the bee product examined, and its effect may be partly due to the various caffeic acids it contains. Pollen, too, exhibited strong antioxidant effects.

  4. A Simple Measure to Assess Hyperinflation and Air Trapping: 1-Forced Expiratory Volume in Three Second / Forced Vital Capacity

    Sermin Börekçi

    2017-04-01

    Full Text Available Background: Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. Aims: To investigate the associations of 1-FEV3/FVC with the spirometric measures and lung volumes that assess small airways dysfunction and reflects hyperinflation and air trapping. Study Design: Retrospective cross-sectional study. Methods: Retrospective assessment of a total of 1110 cases who underwent body plethysmographic lung volume estimations between a time span from 2005 to 2012. Patients were assigned into two groups: firstly by FEV1/FVC (FEV1/FVC <70% vs. FEV1/FVC ≥70%; secondly by FEV3/FVC < lower limits of normal (LLN (FEV3/FVC < LLN vs. FEV3/FVC ≥ LLN. Spirometric indices and lung volumes measured by whole-body plethysmography were compared in groups. Also the correlation of spirometric indices with measured lung volumes were assessed in the whole-study population and in subgroups stratified according to FEV1/FVC and FEV3/FVC. Results: Six hundred seven (54.7% were male and 503 (45.3% were female, with a mean age of 52.5±15.6 years. Mean FEV3/FVC and 1-FEV3/FVC were 87.05%, 12.95%, respectively. The mean 1-FEV3/FVC was 4.9% in the FEV1/FVC ≥70% group (n=644 vs. 24.1% in the FEV1/FVC <70% group (n=466. A positive correlation was found between 1-FEV3/FVC and residual volume (r=0.70; p<0.0001, functional residual capacity-pleth (r=0.61; p<0.0001, and total lung capacity (r=0.47; p<0.0001. 1-FEV3/FVC was negatively correlated with forced expiratory flow25-75 (r=−0.84; p<0.0001. The upper limit of 95% confidence interval for 1-FEV3/FVC was 13.7%. 1-FEV3/FVC showed significant correlations with parameters of air trapping and hyperinflation measured by whole-body plethysmography. Importantly, these correlations were higher in study participants with FEV1/FVC <70% or FEV3/FVC

  5. Delayed Effect of Blood-Flow-Restricted Resistance Training on Rapid Force Capacity

    Nielsen, Jakob Lindberg; Frandsen, Ulrik; Prokhorova, Tatyana

    2017-01-01

    of knee extensor exercise (20%1RM) to concentric failure during concurrent BFR of the thigh (100mmHg), while eight work-matched controls (21.9±3.0 years) trained without BFR (CON). Twenty-three training sessions were performed within 19 days. Maximal slow and fast knee joint velocity muscle strength......PURPOSE: The aim of the present study was to investigate the effect and time course of high-frequent low-load resistance training with blood-flow restriction (BFR) on rapid force capacity (i.e. rate of torque development (RTD)). METHODS: Ten male subjects (22.8±2.3 years) performed four sets...... and rapid force capacity (e.g. RTD) as well as evoked twitch contractile parameters was assessed before (Pre) and 5 and 12 days after training (Post5, Post12). Muscle biopsies were obtained Pre, after 8 days (Mid8) and 3 and 10 days post training (Post3, Post10) to examine changes in myofiber area...

  6. Phenolic Content and Antioxidant Capacity in Algal Food Products

    Ludmila Machu

    2015-01-01

    Full Text Available The study objective was to investigate total phenolic content using Folin-Ciocalteu’s method, to assess nine phenols by HPLC, to determine antioxidant capacity of the water soluble compounds (ACW by a photochemiluminescence method, and to calculate the correlation coefficients in commercial algal food products from brown (Laminaria japonica, Eisenia bicyclis, Hizikia fusiformis, Undaria pinnatifida and red (Porphyra tenera, Palmaria palmata seaweed, green freshwater algae (Chlorella pyrenoidosa, and cyanobacteria (Spirulina platensis. HPLC analysis showed that the most abundant phenolic compound was epicatechin. From spectrophotometry and ACW determination it was evident that brown seaweed Eisenia bicyclis was the sample with the highest phenolic and ACW values (193 mg·g−1 GAE; 7.53 µmol AA·g−1, respectively. A linear relationship existed between ACW and phenolic contents (r = 0.99. Some algal products seem to be promising functional foods rich in polyphenols.

  7. Capacity-coupled multidischarge for atmospheric plasma production

    Mase, Hiroshi; Fujiwara, Tamiya; Sato, Noriyoshi

    2003-01-01

    We propose a method of plasma production by capacity-coupled multidischarge (CCMD) at atmospheric pressure. The discharge gaps in the CCMD consist of a common electrode and a number of compact electrodes (CCE) which are directly coupled with small capacitors for quenching the discharge. A simple CCE structure is provided by a cylindrical capacitor, the inner conductor of which is used as a gap electrode. A short pulse discharge is observed to appear homogeneously at each CCE. A charge transfer for the single-pulsed discharge is 10-100 times as large as that of the conventional dielectric barrier discharge. A high efficiency of ozone production has been confirmed in the CCMD using O 2 gas. A device configuration of the CCMD is quite flexible with respect to its geometrical shape and size. The CCMD could be used to produce plasmas for various kinds of industrial applications at atmospheric pressure

  8. The impact of production capacity utilization on metallurgical companies financing

    J. Kutáč

    2013-01-01

    Full Text Available The most important and the most problematic in-house sources of financing of metallurgical companies are profit and depreciations. In the event that the aggregate value of the economic result and depreciations goes over to negative values, then this kind of in-house financing ceases to increase Cash Flow of the company but, on the contrary, it will cause its reduction. It means that this type of financing is to some extent uncertain, particularly in times of crisis, when there are noticeable fluctuations in sales volumes, leading to a significant influence of the volume of production on the amount of profit. The article discusses the impact of production capacity utilization on metallurgical companies financing.

  9. Effect of Chamber Wall Proximity on Radiometer Force Production (Preprint)

    Selden, N. P; Gimelshein, N. E; Gimelshein, S. F; Ketsdever, A. D

    2008-01-01

    ... on a given radiometer configuration in both the free molecule and transitional regimes. The contribution of the chamber walls to both the flowfield structure and radiometric force production were examined for helium, argon, and nitrogen test gases...

  10. Usefulness of phrenic latency and forced vital capacity in patients with ALS with latent respiratory dysfunction.

    Kwon, Soonwook; Min, Ju-Hong; Cho, Hye-Jin; Joo, Byung-Euk; Cho, Eun Bin; Seok, Jin Myoung; Kim, Min-Ji; Kim, Byoung Joon

    2015-07-01

    The pulmonary function test (PFT) is a non-invasive and easily available technique to assess respiratory function in patients with amyotrophic lateral sclerosis (ALS); however, patients with dyspnea sometimes show normal PFT findings. Herein, we investigated whether phrenic nerve conduction study (NCS) and PFT are useful to evaluate respiratory function of patients with ALS with normal value ranges in the PFT. We prospectively enrolled 34 patients with definite or probable ALS, who showed FVC (%) ⩾80 of predicted and 78 healthy subjects. PFT and phrenic NCS were performed with the measurement of forced vital capacity (FVC, %), forced expiratory volumes in 1s (FEV1, %), FEV1/FCV ratio (%), and phrenic compound muscle action potential amplitude, and latency. Compared to healthy controls, ALS patients showed delayed phrenic nerve latency and the decrease of FVC (%) (p=0.006 and pphrenic latency (AUC=0.7655) and FVC (%) (AUC=0.8239) discriminated ALS patients from healthy subjects. We demonstrated that ALS patients had early respiratory dysfunction, despite normal PFT findings. Phrenic latency and FVC (%) can be helpful to discriminate ALS patients with latent respiratory dysfunction from healthy subjects. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  11. Improvement of Stand Jig Sealer and Its Increased Production Capacity

    Soebandrija, K. E. N.; Astuti, S. W. D.

    2014-03-01

    This paper has the objective to prove that improvement of Stand Jig Sealer can lead to the cycle time target as part of Improvement efforts and its Productivity. Prior researches through prior journals both classics journal such as Quesnay (1766) and Solow (1957) and updated journal such as Reikard (2011) researches, are mentioned and elaborated. Precisely, the research is narrowed down and specified into automotive industry and eventually the software related of SPSS and Structural Equation Modeling ( SEM ). The analysis and its method are conducted through the calculation working time. The mentioned calculation are reinforced with the hypothesis test using SPSS Version 19 and involve parameters of production efficiency, productivity calculation, and the calculation of financial investments. The results obtained are augmented achievement of cycle time target ≤ 80 seconds posterior to improvement stand jig sealer. The result from calculation of SPSS-19 version comprise the following aspects: the one-sided hypothesis test is rejection of Ho:μ≥80 seconds, the correlation rs=0.84, regression y = 0.159+0.642x, validity R table = 0.4438, reliability value of Cronbach's alpha = 0.885>0.70, independence (Chi Square) Asymp. Sig=0.028financial analysis (NPV 2,340,596>0, PI 2.04>1, IRR 45.56%>i=12.68%, PP=1.86). The Mentioned calculation results support the hypothesis and ultimately align with the objective of this paper to prove that improvement of Stand Jig Sealer and its relation toward the cycle time target. Precisely, the improvement of production capacity of PT. Astra Daihatsu Motor.

  12. Effect of fatigue on force production and force application technique during repeated sprints.

    Morin, Jean-Benoit; Samozino, Pierre; Edouard, Pascal; Tomazin, Katja

    2011-10-13

    We investigated the changes in the technical ability of force application/orientation against the ground vs. the physical capability of total force production after a multiple-set repeated sprints series. Twelve male physical education students familiar with sprint running performed four sets of five 6-s sprints (24s of passive rest between sprints, 3min between sets). Sprints were performed from a standing start on an instrumented treadmill, allowing the computation of vertical (F(V)), net horizontal (F(H)) and total (F(Tot)) ground reaction forces for each step. Furthermore, the ratio of forces was calculated as RF=F(H)F(Tot)(-1), and the index of force application technique (D(RF)) representing the decrement in RF with increase in speed was computed as the slope of the linear RF-speed relationship. Changes between pre- (first two sprints) and post-fatigue (last two sprints) were tested using paired t-tests. Performance decreased significantly (e.g. top speed decreased by 15.7±5.4%; Pmultiple-set repeated sprint series, both the total force production capability and the technical ability to apply force effectively against the ground are altered, the latter to a larger extent than the former. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Modeling intermediate product selection under production and storage capacity limitations in food processing

    Kilic, Onur Alper; Akkerman, Renzo; Grunow, Martin

    2009-01-01

    In the food industry products are usually characterized by their recipes, which are specified by various quality attributes. For end products, this is given by customer requirements, but for intermediate products, the recipes can be chosen in such a way that raw material procurement costs and pro...... with production and inventory planning, thereby considering the production and storage capacity limitations. The resulting model can be used to solve an important practical problem typical for many food processing industries.......In the food industry products are usually characterized by their recipes, which are specified by various quality attributes. For end products, this is given by customer requirements, but for intermediate products, the recipes can be chosen in such a way that raw material procurement costs...... and processing costs are minimized. However, this product selection process is bound by production and storage capacity limitations, such as the number and size of storage tanks or silos. In this paper, we present a mathematical programming approach that combines decision making on product selection...

  14. A socioecological analysis of the determinants of national public health nutrition work force capacity: Australia as a case study.

    Hughes, Roger

    2006-01-01

    This article uses a socioecological analytical approach to assess the capacity of the public health nutrition work force in Australia as a prelude to work force development strategy planning. It demonstrates how the socioecological model can be used to assess and inform the development of the infrastructure required for effective public health nutrition effort. An interpretive case study method was used involving triangular analysis of quantitative and qualitative data from multiple sources including semistructured interviews with advanced-level practitioners, literature review, a cross-sectional national work force survey, and position description audit and consensus development using a Delphi study. The findings of this analysis indicate that the Australian public health nutrition work force's capacity to effectively address priority nutrition issues is limited by determinants that can be categorized as relating to human resource infrastructure, organizational and policy environments, intelligence access and use, practice improvement and learning systems, and work force preparation. This socioecological analysis supports an intelligence-based focus for work force development effort in Australia and a conceptual framework for work force capacity assessment with potential applications in other countries.

  15. The efficiency of aerodynamic force production in Drosophila.

    Lehmann, F O

    2001-12-01

    Total efficiency of aerodynamic force production in insect flight depends on both the efficiency with which flight muscles turn metabolic energy into muscle mechanical power and the efficiency with which this power is converted into aerodynamic flight force by the flapping wings. Total efficiency has been estimated in tethered flying fruit flies Drosophila by modulating their power expenditures in a virtual reality flight simulator while simultaneously measuring stroke kinematics, locomotor performance and metabolic costs. During flight, muscle efficiency increases with increasing flight force production, whereas aerodynamic efficiency of lift production decreases with increasing forces. As a consequence of these opposite trends, total flight efficiency in Drosophila remains approximately constant within the kinematic working range of the flight motor. Total efficiency is broadly independent of different profile power estimates and typically amounts to 2-3%. The animal achieves maximum total efficiency near hovering flight conditions, when the beating wings produce flight forces that are equal to the body weight of the insect. It remains uncertain whether this small advantage in total efficiency during hovering flight was shaped by evolutionary factors or results from functional constraints on both the production of mechanical power by the indirect flight muscles and the unsteady aerodynamic mechanisms in flapping flight.

  16. The influence of Lampblack on capacity retention in Pb/PbSO/sub 4/ electrodes with forced flow of electrolyte

    Borger, W.; Hullmeine, U.

    1984-10-01

    High active material utilization of Pb/PbSO/sub 4/ electrodes after formation in the range of 170 - 120 Ah/kg is obtained when these electrodes are discharged at 50-200 A/kg current density with forced flow of electrolyte. Decline of capacity was observed on further cycling at high current density and forced flow of electrolyte. The extent of capacity decline in these electrodes is largely influenced by the amount of additives in the active material, e.g. lampblack and expander.

  17. Bite force and occlusal stress production in hominin evolution.

    Eng, Carolyn M; Lieberman, Daniel E; Zink, Katherine D; Peters, Michael A

    2013-08-01

    Maximum bite force affects craniofacial morphology and an organism's ability to break down foods with different material properties. Humans are generally believed to produce low bite forces and spend less time chewing compared with other apes because advances in mechanical and thermal food processing techniques alter food material properties in such a way as to reduce overall masticatory effort. However, when hominins began regularly consuming mechanically processed or cooked diets is not known. Here, we apply a model for estimating maximum bite forces and stresses at the second molar in modern human, nonhuman primate, and hominin skulls that incorporates skeletal data along with species-specific estimates of jaw muscle architecture. The model, which reliably estimates bite forces, shows a significant relationship between second molar bite force and second molar area across species but does not confirm our hypothesis of isometry. Specimens in the genus Homo fall below the regression line describing the relationship between bite force and molar area for nonhuman anthropoids and australopiths. These results suggest that Homo species generate maximum bite forces below those predicted based on scaling among australopiths and nonhuman primates. Because this decline occurred before evidence for cooking, we hypothesize that selection for lower bite force production was likely made possible by an increased reliance on nonthermal food processing. However, given substantial variability among in vivo bite force magnitudes measured in humans, environmental effects, especially variations in food mechanical properties, may also be a factor. The results also suggest that australopiths had ape-like bite force capabilities. Copyright © 2013 Wiley Periodicals, Inc.

  18. Effect of slope height and horizontal forces on the bearing capacity of strip footings near slopes in cohesionless soil

    Krabbenhøft, Sven; Damkilde, Lars; Krabbenhøft, Kristian

    2016-01-01

    , and in such cases the bearing capacity of the footing cannot be found using the existing methods. The present work comprises finite element based upper- and lower-bound calculations, using the geotechnical software OptumG2 to investigate the effect of the slope height and horizontal forces on the total bearing...... capacity, both without and with using superposition as presupposed in the traditional bearing capacity equation. The results for friction angles 30, 35 and 40 degrees, slope inclinations 1:2, 1:3 and 1:4, for selfweight and surcharge are given as charts showing the slope inclination factors suitable...

  19. Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality.

    Yang, William C; Lu, Jiuyi; Kwiatkowski, Chris; Yuan, Hang; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

    2014-01-01

    Volumetric productivity and product quality are two key performance indicators for any biopharmaceutical cell culture process. In this work, we showed proof-of-concept for improving both through the use of alternating tangential flow perfusion seed cultures coupled with high-seed fed-batch production cultures. First, we optimized the perfusion N-1 stage, the seed train bioreactor stage immediately prior to the production bioreactor stage, to minimize the consumption of perfusion media for one CHO cell line and then successfully applied the optimized perfusion process to a different CHO cell line. Exponential growth was observed throughout the N-1 duration, reaching >40 × 10(6) vc/mL at the end of the perfusion N-1 stage. The cultures were subsequently split into high-seed (10 × 10(6) vc/mL) fed-batch production cultures. This strategy significantly shortened the culture duration. The high-seed fed-batch production processes for cell lines A and B reached 5 g/L titer in 12 days, while their respective low-seed processes reached the same titer in 17 days. The shortened production culture duration potentially generates a 30% increase in manufacturing capacity while yielding comparable product quality. When perfusion N-1 and high-seed fed-batch production were applied to cell line C, higher levels of the active protein were obtained, compared to the low-seed process. This, combined with correspondingly lower levels of the inactive species, can enhance the overall process yield for the active species. Using three different CHO cell lines, we showed that perfusion seed cultures can optimize capacity utilization and improve process efficiency by increasing volumetric productivity while maintaining or improving product quality. © 2014 American Institute of Chemical Engineers.

  20. Natural gas productive capacity for the lower 48 states, 1982--1993

    1993-01-01

    The purpose of this report is to analyze monthly natural gas wellhead productive capacity and project this capacity for 1992 and 1993, based upon historical production data through 1991. Productive capacity is the volume of gas that can be produced from a well, reservoir, or field during a given period of time against a certain wellhead back-pressure under actual reservoir conditions excluding restrictions imposed by pipeline capacity, contracts, or regulatory bodies. For decades, natural gas supplies and productive capacity have been adequate, although in the 1970's the capacity surplus was small because of market structure (both interstate and intrastate), increasing demand, and insufficient drilling. In the early 1980's, lower demand together with increased drilling led to a large surplus of natural gas capacity. After 1986, this large surplus began to decline as demand for gas increased, gas prices dropped, and gas well completions dropped sharply. In late December 1989, this surplus decline, accompanied by exceptionally high demand and temporary weather-related production losses, led to concerns about the adequacy of monthly productive capacity for natural gas. This study indicates that monthly productive capacity will drop sharply during the 1992-1993 period. In the low gas price, low drilling case, gas productive capacity and estimated production demand will be roughly equal in December 1993. In base and high drilling cases, monthly productive capacity should be able to meet normal production demands through 1993 in the lower 48 States. Exceptionally high peak-day or peak-week production demand might not be met because of physical limitations. Beyond 1993, as the capacity of currently producing wells declines, a sufficient number of wells and/or imports must be added each year in order to ensure an adequate gas supply

  1. Questions cloud outlook for oil production capacity growth in the Middle East

    Tippee, B.

    1994-01-01

    Future expansion of crude oil production capacity in the Middle East is anything but certain-at least with crude prices at recent levels. There is little doubt that the world will need more production capacity than now exists unless petroleum consumption sags. And there is even less doubt about where prospects are best for production capacity growth. The paper discusses the normal surplus, growing demand, financial conditions, and political stability

  2. Management model of productive capacity: integrating theory of constraints and the global operational efficiency index (IROG

    Diego Augusto Pacheco

    2012-08-01

    Full Text Available This paper presents a model of management capacity in productive systems integrating the concepts of the Theory of Constraints and Total Productive Maintenance (TPM. The main objective of this study is to discuss and propose a model of management capacity, able to answer the following key questions: i capacity indicators which should be considered and how to measure them to measure the productive capacity of manufacturing systems? ii what is the real productive capacity of the system analyzed under a determined relationship between capacity and demand? The discussion of the proposed model is relevant because the definition of productive capacity system enables better management of resources and capabilities, improve production scheduling on the factory floor and meeting the demands imposed by the market. This paper presents the proposition of using the Operating Income Index Global (IROG with a different approach from traditional literature dealing with the theme, presented by Nakajima (1988. The results of this paper enable to develop a model to determine the capacity of the production system and the impact on the productive capacity of the entire system, not to consider the quality conformances that occur after the bottleneck resource of the production flow.

  3. Forced vital capacity predicts morbidity and mortality in adults with repaired tetralogy of Fallot.

    Cohen, Katie E; Buelow, Matthew W; Dixon, Jennifer; Brazauskas, Ruta; Cohen, Scott B; Earing, Michael G; Ginde, Salil

    2017-07-01

    Abnormal lung function characterized by a reduced forced vital capacity (FVC) is common in adults with repaired tetralogy of Fallot (TOF) and is associated with previous thoracotomies and sternotomies. The impact of abnormal lung function on clinical outcomes in adult patients with repaired TOF is unclear. The aim of this study was to determine the impact of abnormal lung function on the outcome of hospitalization and death in adults with repaired TOF when analyzed with other traditional cardiac risk factors. Retrospective study of adults with repaired TOF, who underwent spirometry between 2000 and 2014. FVC < 60% of predicted was categorized as moderate-to-severely reduced lung function. Primary outcome measure was the combined clinical endpoint of death, cardiac transplantation, or nonelective hospitalization for primary cardiac or respiratory indication. A total of 122 patients were included. Average age at spirometry testing was 31 ± 10.1 years. FVC was < 60% predicted in 23 (19%) patients. During a mean follow-up period of 3.97 ± 2.65 years, 23 (19%) patients reached the combined clinical outcome of nonelective hospitalization and/or death. FVC < 60% predicted was independently associated with the risk for the combined clinical outcome (RR 6.68 (95% CI 2.49-17.94), P < .001). Abnormal pulmonary function characterized by reduced FVC is common in adults with repaired TOF. Patients with FVC < 60% predicted had a 6 times higher rate of hospitalization and/or death compared to those with FVC ≥ 60%. © 2017 Wiley Periodicals, Inc.

  4. Maintenance Production Demand and Capacity Analysis of Third Maintenance Battalion

    2017-12-01

    Delivery T/E Table of Equipment TFSMS Total Force Structure Management System TFSP Total Force Structure Process TM Technical Manual T/O Table of...exercises each year, both on Okinawa and throughout the Pacific theater. When equipment requires maintenance beyond the organizational -level...demand was analyzed based on customer cycle time (i.e., time that equipment was in Third Maintenance Battalion custody), maintenance cycle time during

  5. Alluvial diamond resource potential and production capacity assessment of Mali

    Chirico, Peter G.; Barthelemy, Francis; Kone, Fatiaga

    2010-01-01

    In May of 2000, a meeting was convened in Kimberley, South Africa, and attended by representatives of the diamond industry and leaders of African governments to develop a certification process intended to assure that rough, exported diamonds were free of conflictual concerns. This meeting was supported later in 2000 by the United Nations in a resolution adopted by the General Assembly. By 2002, the Kimberley Process Certification Scheme (KPCS) was ratified and signed by diamond-producing and diamond-importing countries. Over 70 countries were included as members of the KPCS at the end of 2007. To prevent trade in "conflict diamonds" while protecting legitimate trade, the KPCS requires that each country set up an internal system of controls to prevent conflict diamonds from entering any imported or exported shipments of rough diamonds. Every diamond or diamond shipment must be accompanied by a Kimberley Process (KP) certificate and be contained in tamper-proof packaging. The objective of this study was (1) to assess the naturally occurring endowment of diamonds in Mali (potential resources) based on geological evidence, previous studies, and recent field data and (2) to assess the diamond-production capacity and measure the intensity of mining activity. Several possible methods can be used to estimate the potential diamond resource. However, because there is generally a lack of sufficient and consistent data recording all diamond mining in Mali and because time to conduct fieldwork and accessibility to the diamond mining areas are limited, four different methodologies were used: the cylindrical calculation of the primary kimberlitic deposits, the surface area methodology, the volume and grade approach, and the content per kilometer approach. Approximately 700,000 carats are estimated to be in the alluvial deposits of the Kenieba region, with 540,000 carats calculated to lie within the concentration grade deposits. Additionally, 580,000 carats are estimated to have

  6. Entrepreneurial University Perspective: Tracking Labor Force Capacity to Support Industrialization Processes in the Emerging Markets, Evidence from Kazakhstan Data

    Dilara Orynbassarova

    2017-01-01

    Full Text Available Industrialisation is considered as main engine of growth in economic development of the most emerging markets. This is especially true for Central Asian transitional countries as Kazakhstan, which obtained independence from the Soviet Union in 1991. For enhancing country’s competitiveness potential, Kazakhstan National Program for 2010-2014 aimed to accelerate industrial-innovative development of the country. While many papers published about the importance of industrialization activities in Kazakhstan, few have focused on examining the current capacity of labor market to meet the industry demand. Main aim of this paper was to investigate if current manpower is adequate to maintain the planned rate of growth in the country. Higher level of economic production led to higher demand of engineering labor force. High demand with low frequency supply created an imbalance in the labor market that resulted what we see as shortage of technically skilled labor. Low frequency of supply is influenced by such factors as high engineers’ outflow rate, low students enrolment and graduation rates, and lack of practical skills of the graduates hired.

  7. THE TECHNIQUE OF DIAGNOSTICS OF THE PRODUCTION CAPACITY OF THE ORGANIZATION

    E. S. Popova

    2014-01-01

    Full Text Available In the article due to the need for diagnostics of the production capacity of the organization. Formed methodological framework for evaluating the production potential of the organization. Research capacity will also enable the organization to timely respond to current changes. A classification of types of diagnostics of the production capacity of the organization according to the following criteria: timing, goals, content, purpose results. The article discusses the economic and organizational diagnosis of the production capacity of the organization. Economic diagnosis is based on the calculation of indicators of use of resources of the organization. Organizational diagnosis assesses the security of the organization's activities. Diagnosis productive capacity is the basis for improvement of the organization's activities. Defined diagnostics of the production capacity of the organization. Justified the selection stages of the research production potential. The first stage is the preliminary diagnosis. The second stage provides for the rapid diagnosis of production potential. At the third stage it is advisable to perform problem diagnosis. Problem diagnosis consists of economic and organizational diagnosis. Economic diagnosis assesses the state of the elements of the production potential of the organization. Organizational diagnostics analyses provide productive capacity. The fourth stage is represented by the solution of the problems of utilization of production capacity. Each stage is considered, has its content and specific diagnostic methods of production potential. This method allows determining the state of the elements, the efficiency of utilization of production capacity. The estimation of the production potential is based on the application of utility theory. This assessment provides a definition of the criteria and the scale of usefulness. This will allow you to measure the production potential numerically. In the end, it is revealed

  8. Association of Forced Vital Capacity with the Developmental Gene NCOR2.

    Cosetta Minelli

    Full Text Available Forced Vital Capacity (FVC is an important predictor of all-cause mortality in the absence of chronic respiratory conditions. Epidemiological evidence highlights the role of early life factors on adult FVC, pointing to environmental exposures and genes affecting lung development as risk factors for low FVC later in life. Although highly heritable, a small number of genes have been found associated with FVC, and we aimed at identifying further genetic variants by focusing on lung development genes.Per-allele effects of 24,728 SNPs in 403 genes involved in lung development were tested in 7,749 adults from three studies (NFBC1966, ECRHS, EGEA. The most significant SNP for the top 25 genes was followed-up in 46,103 adults (CHARGE and SpiroMeta consortia and 5,062 children (ALSPAC. Associations were considered replicated if the replication p-value survived Bonferroni correction (p<0.002; 0.05/25, with a nominal p-value considered as suggestive evidence. For SNPs with evidence of replication, effects on the expression levels of nearby genes in lung tissue were tested in 1,111 lung samples (Lung eQTL consortium, with further functional investigation performed using public epigenomic profiling data (ENCODE.NCOR2-rs12708369 showed strong replication in children (p = 0.0002, with replication unavailable in adults due to low imputation quality. This intronic variant is in a strong transcriptional enhancer element in lung fibroblasts, but its eQTL effects could not be tested due to low imputation quality in the eQTL dataset. SERPINE2-rs6754561 replicated at nominal level in both adults (p = 0.036 and children (p = 0.045, while WNT16-rs2707469 replicated at nominal level only in adults (p = 0.026. The eQTL analyses showed association of WNT16-rs2707469 with expression levels of the nearby gene CPED1. We found no statistically significant eQTL effects for SERPINE2-rs6754561.We have identified a new gene, NCOR2, in the retinoic acid signalling pathway pointing

  9. New product introduction and capacity investment by incumbents: Effects of size on strategy

    Dawid, H.; Kopel, M.; Kort, P.M.

    2013-01-01

    We analyze a duopoly where capacity-constrained firms offer an established product and have the option to offer an additional new and differentiated product. We show that the firm with the smaller capacity on the established market has a higher incentive to innovate and reaches a larger market share

  10. Improvement of meat production capacity in reindeer farming

    C. J. Petersson

    1990-09-01

    Full Text Available The poster describes the main activities in a joint Swedish-Norwegian research project. The ultimate purpose is to develope tools for individual production control and flock management in domestic reindeer production.

  11. About productive force and labour productivity (questions of the theory and practice

    Kulik V.I.

    2018-03-01

    Full Text Available the authors consider two intermediaries: the intermediary between the world of the nature and the person – means of work or "fixed capital" of a society as productive force of social activities, and the intermediary inside a society – cost in the form of money without what it is impossible to define labour productivity and structural transformations in a society. The article gives engineering understanding of productive force and productivity of the process equipment by the example of calculation and a choice of the automatic transfer line.

  12. Saldanha Bay, South Africa III: new production and carrying capacity ...

    It is estimated that the total annual production of mussels and oysters, respectively, for a 1 000-ha cultivation area is approximately 40 000–53 000 t y–1 (mainly Mytilus galloprovincialis) and 4 600–6 000 t y–1 (Crassotrea gigas). The combined total production figures constitute only 24–31% of the surplus new production.

  13. Natural gas productive capacity for the lower 48 States, 1980 through 1995

    1994-01-01

    The purpose of this report is to analyze monthly natural gas wellhead productive capacity in the lower 48 States from 1980 through 1992 and project this capacity from 1993 through 1995. For decades, natural gas supplies and productive capacity have been adequate to meet demand. In the 1970's the capacity surplus was small because of market structure (split between interstate and intrastate), increasing demand, and insufficient drilling. In the early 1980's, lower demand, together with increased drilling, led to a large surplus capacity as new productive capacity came on line. After 1986, this large surplus began to decline as demand for gas increased, gas prices fell, and gas well completions dropped sharply. In late December 1989, the decline in this surplus, accompanied by exceptionally high demand and temporary weather-related production losses, led to concerns about the adequacy of monthly productive capacity for natural gas. These concerns should have been moderated by the gas system's performance during the unusually severe winter weather in March 1993 and January 1994. The declining trend in wellhead productive capacity is expected to be reversed in 1994 if natural gas prices and drilling meet or exceed the base case assumption. This study indicates that in the low, base, and high drilling cases, monthly productive capacity should be able to meet normal production demands through 1995 in the lower 48 States (Figure ES1). Exceptionally high peak-day or peak-week production demand might not be met because of physical limitations such as pipeline capacity. Beyond 1995, as the capacity of currently producing wells declines, a sufficient number of wells and/or imports must be added each year in order to ensure an adequate gas supply

  14. Knowledge of Repetitions Range Affects Force Production in Trained Females

    Israel Halperin, Saied J. Aboodarda, Fabien A. Basset, David G. Behm

    2014-12-01

    Full Text Available Most studies have examined pacing strategies with cyclical activities (running and cycling. It has been demonstrated that males employ different pacing strategies during repeated maximal voluntary contractions (MVCs dependent upon a known endpoint. Since different fatiguing mechanisms have been identified between the genders, it is not known if females use comparable pacing strategies. The purpose of this study was to examine if informing female subjects regarding the number of MVCs to perform would affect force and electromyography (EMG. Twenty well-trained females completed 3 fatiguing protocols in a randomized order. In the control condition participants were informed they would perform twelve MVCs and then actually completed twelve. In the unknown condition they were not told how many MVCs to perform but were stopped after twelve. In the deception condition they were initially informed to perform 6 MVCs, but after the 6th MVC they were asked to perform a few more MVCs and were stopped after twelve. During the first 6 MVCs, forces in the deception condition were greater compared to the unknown (p = 0.021, ES = 0.65, 5% and control (p = 0.022, ES = 0.42, 3% conditions. No differences were found between conditions in the last 6 MVCs. A main effect for repetitions showed force deficits during the first 6 MVCs (p = 0.000, ES = 1.81, 13% and last 6 MVCs (p = 0.05, ES = 0.34, 3%. No differences were found between conditions in biceps and triceps EMG. However, EMG decreased during the first 6 MVCs for biceps (p = 0.001, ES = 1.0, 14% and triceps (p = 0.001, ES = 0.76, 14% across conditions. No differences were found in the last 6 MVCs. The anticipation of performing fewer MVCs led to increased force, whereas no endpoint led to decreased force production.

  15. Building Partner Capacity/Security Force Assistance: A New Structural Paradigm

    Wuestner, Scott G

    2009-01-01

    ...), which would function much like our military reserve. It would ease the burden on the Armed Forces by allowing the hiring of civilians with critical skills to serve on missions abroad when America needs...

  16. Assessment of Production Skill Acquisition and Strategy for Capacity ...

    First Lady

    The study was a survey research which investigated the production skills possessed by .... like creative thinking, decision making, marketing etc. (Olutoyin ... difficult to get teaching jobs or set up and handle their own businesses which resulted ...

  17. Land Potential Productivity and Population Carrying Capacity of Yan’an City

    Liu, Xiaoling; Zhang, Wei

    2013-01-01

    The productivity attenuation method is adopted to calculate land potential productivity of counties of Yan’an City and calculate population carrying capacity at current productivity level. Rsults shows that high photosynthetic potential productivity area and high light and temperature potential productivity area are mainly situated in the north, while high climatic potential area and high land potential productivity area are mainly concentrated in the south. From solar radiation, moisture a...

  18. Embryo mechanics: balancing force production with elastic resistance during morphogenesis.

    Davidson, Lance A

    2011-01-01

    Morphogenesis requires the spatial and temporal control of embryo mechanics, including force production and mechanical resistance to those forces, to coordinate tissue deformation and large-scale movements. Thus, biomechanical processes play a key role in directly shaping the embryo. Additional roles for embryo mechanics during development may include the patterning of positional information and to provide feedback to ensure the success of morphogenetic movements in shaping the larval body and organs. To understand the multiple roles of mechanics during development requires familiarity with engineering principles of the mechanics of structures, the viscoelastic properties of biomaterials, and the integration of force and stress within embryonic structures as morphogenesis progresses. In this chapter, we review the basic engineering principles of biomechanics as they relate to morphogenesis, introduce methods for quantifying embryo mechanics and the limitations of these methods, and outline a formalism for investigating the role of embryo mechanics in birth defects. We encourage the nascent field of embryo mechanics to adopt standard engineering terms and test methods so that studies of diverse organisms can be compared and universal biomechanical principles can be revealed. Copyright © 2011 Elsevier Inc. All rights reserved.

  19. Effect of forced swimming stress on count, motility and fertilization capacity of the sperm in adult rats

    Ghasem Saki

    2009-01-01

    Full Text Available Aims: The purpose of this study was to determine whether 50 days of forced swimming stress applied to adult male rats affects count, motility and fertilization capacity of sperm. Settings and Design: It is a prospective study designed in vitro. Materials and Methods: A total 30 adult male wistar rats were used in this study. All rats were divided into two equal groups (n = 15: (1 control group and (2 experimental group. Animals of the experimental group were submitted to force swimming stress for 3 min in water at 32°C daily for 50 days. Then, all male rats were sacrificed, the right epididymides were removed and sperm concentration and motility were determined. The sperm suspension was added to the ova. Fertilization capacity was assessed by counting two-cell embryos 24-26 h after completion of fertilization in vitro. Statistical Analysis Used: Data are reported as mean ± SD and percentage. The difference between the control and experimental groups was determined by the unpaired t-test. Results: The mean and standard deviation of sperm concentration in the control and experimental groups were 60.8 ± 9.3 10 6 /ml and 20.4 ± 5.3 10 6 /ml, respectively. There was a statistical difference of P < 0.05 between the two groups in terms of sperm concentration. The percentage of motility in the experimental group was significantly different ( P < 0.05. The same results were obtained in case of fertility ( P < 0.05. Stress caused by forced swimming was observed by a significant increase in the latency of the pain response in the hot-plate test ( P < 0.05. Conclusions: These results suggest that forced swimming stress in time course equal or more than spermatogenesis period, i.e. 48-50 days in the rat will be significantly effective to reduce the number and motility of sperms as well as the fertilization capacity.

  20. Industrial Law and the Productive Capacity of Labour in Nigeria

    Matthew Enya Nwocha

    2017-06-01

    Full Text Available This Paper has discussed the various employment laws in the country and the inherent defects in them that have impacted negatively on staff productivity. The Paper came against the background of the low productive output of the Nigerian worker that has adversely affected the growth of the national economy and created room for fraud and corruption in the public service as well as the private sector. The Paper has found that aside of defective labour laws, the mentality of Nigerian courts to labour disputes, the negative attitude of Nigerian workers and poor work ethics, and the poor conditions of service in the labour sector all contribute to low output and productivity. Therefore, the Paper has suggested ways that these negative trends can be reversed among them, the amendment of the extant industrial laws and improvement of the working conditions of the Nigerian employee.

  1. Plant Design Nuclear Fuel Element Production Capacity Optimization to Support Nuclear Power Plant in Indonesia

    Bambang Galung Susanto

    2007-01-01

    The optimization production capacity for designing nuclear fuel element fabrication plant in Indonesia to support the nuclear power plant has been done. From calculation and by assuming that nuclear power plant to be built in Indonesia as much as 12 NPP and having capacity each 1000 MW, the optimum capacity for nuclear fuel element fabrication plant is 710 ton UO 2 /year. The optimum capacity production selected, has considered some aspects such as fraction batch (cycle, n = 3), length of cycle (18 months), discharge burn-up value (Bd) 35,000 up 50,000 MWD/ton U, enriched uranium to be used in the NPP (3.22 % to 4.51 %), future market development for fuel element, and the trend of capacity production selected by advances country to built nuclear fuel element fabrication plant type of PWR. (author)

  2. Improving Power System Modeling. A Tool to Link Capacity Expansion and Production Cost Models

    Diakov, Victor [National Renewable Energy Lab. (NREL), Golden, CO (United States); Cole, Wesley [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sullivan, Patrick [National Renewable Energy Lab. (NREL), Golden, CO (United States); Brinkman, Gregory [National Renewable Energy Lab. (NREL), Golden, CO (United States); Margolis, Robert [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    Capacity expansion models (CEM) provide a high-level long-term view at the prospects of the evolving power system. In simulating the possibilities of long-term capacity expansion, it is important to maintain the viability of power system operation in the short-term (daily, hourly and sub-hourly) scales. Production-cost models (PCM) simulate routine power system operation on these shorter time scales using detailed load, transmission and generation fleet data by minimizing production costs and following reliability requirements. When based on CEM 'predictions' about generating unit retirements and buildup, PCM provide more detailed simulation for the short-term system operation and, consequently, may confirm the validity of capacity expansion predictions. Further, production cost model simulations of a system that is based on capacity expansion model solution are 'evolutionary' sound: the generator mix is the result of logical sequence of unit retirement and buildup resulting from policy and incentives. The above has motivated us to bridge CEM with PCM by building a capacity expansion - to - production cost model Linking Tool (CEPCoLT). The Linking Tool is built to onset capacity expansion model prescriptions onto production cost model inputs. NREL's ReEDS and Energy Examplar's PLEXOS are the capacity expansion and the production cost models, respectively. Via the Linking Tool, PLEXOS provides details of operation for the regionally-defined ReEDS scenarios.

  3. Product Evaluation Task Force Phase Two report for CAGR graphite

    Francis, A.J.; Davies, A.

    1991-01-01

    It has been proposed that all Intermediate Level Wastes arising at Sellafield should be encapsulated prior to ultimate disposal. The Product Evaluation Task Force (PETF) was set up to investigate possible encapsulants and to produce an adequate data base to justify the preferred matrices. This report details the work carried out under Phase 2 of the Product Evaluation Task Force programme, on CAGR graphite. Three possible types of encapsulants for CAGR graphites:-Inorganic cements, Polymer cements and Polymers are evaluated using the Kepner Tregoe decision analysis technique. This technique provides a methodology for scoring and ranking alternative options and evaluating any risks associated with an option. The analysis shows that for all four stages of waste management operations ie Storage, Transport, handling and emplacement, Disposal and Process, cement matrices are considerably superior to other potential matrices. A matrix, consisting of three parts Blast Furnace Slag (BFS) to one part Ordinary Portland Cement (OPC) is recommended as the preferred matrix for Phase 3 studies on CAGR graphite. (author)

  4. Ethanol production by immobilized cells with forced substrate supply

    Mitani, Y.; Nishizawa, Y.; Nagai, S.

    1984-01-01

    Ethanol fermentation by a forced substrate supply into an immobilized cell layer was carried out to increase the ethanol production rate and to eliminate the diffusion dependency of substrate supply in an ordinary immobilized cell reaction. Saccharomyces cerevisiae IFO 2347 was immobilized in a mixture of k-carrageenan, locust bean gum, and celite (2: 0.5: 40 wt/vol %). A glucose minimal medium was fed into the immobilized cell layer (5 to 22 mm in thickness) at retention times between 0.6 and 2.8 h under pressure. The stable ethanol fermentation could be maintained for more than 3 weeks with an ethanol yield of 0.48 g ethanol/g glucose and ethanol productivity of 63 g.(l gel)/sup -1/.h/sup -1/ at a retention time of 1.5 h. The yeast cells were well distributed through the gel layer with a vertical gradient, and an average cell density was ca. 8.0 X 10/sup 9/ cells/ml gel, 4-fold higher than that of ordinary immobilized cells. A small filter press reactor was constructed to examine the applicability of ethanol fermentation with this forced substrate supply. The operation could be continued for a month at a retention time of 2 h yielding 96 g/l of ethanol from 200 g/l of glucose. 6 references, 5 figures, 3 tables.

  5. Serum triiodothyronine levels and inflammatory cytokine production capacity

    Rozing, Maarten P.; Westendorp, Rudi G J; Maier, Andrea B.; Wijsman, Carolien A.; Frölich, Marijke; De Craen, Anton J M; Van Heemst, Diana

    Increasing evidence suggests that pro-inflammatory cytokines are at play in lowering peripheral thyroid hormone levels during critical illness. Conversely, thyroid hormones have been suggested to enhance production of inflammatory cytokines. In view of these considerations, we hypothesized a mutual

  6. Regional softwood sawmill processing variables as influenced by productive capacity

    P. H. Steele; F. G. Wagner; K. E. Skog

    The relationship between annual softwood sawmill production and lumber processing variables was examined using data from Sawmill Improvement Program (SIP) studies of 650 softwood mills. The variables were lumber recovery factor (LRF); headrig and resaw kerf width; total sawing variation, rough green size, and oversizing-undersizing for 4/4 and 8/4 lumber; planer...

  7. Soft wheat and flour products methods review: solvent retention capacity equation correction

    This article discusses the results of a significant change to calculations made within AACCI Approved methods 56-10 and 56-11, the Alkaline Water Retention Capacity (AWRC) test and the Solvent Retention Capacity (SRC) test. The AACCI Soft Wheat and Flour Products Technical Committee reviewed propos...

  8. 76 FR 24025 - Information Collection; Prohibition on Acquisition of Products Produced by Forced or Indentured...

    2011-04-29

    ... Acquisition of Products Produced by Forced or Indentured Child Labor AGENCY: Department of Defense (DOD... acquisition of products produced by forced or indentured child labor. DATES: Submit comments on or before..., Prohibition on Acquisition of Products Produced by Forced or Indentured Child Labor, signed by the President...

  9. 76 FR 42709 - Submission for OMB Review; Prohibition on Acquisition of Products Produced by Forced or...

    2011-07-19

    ... on Acquisition of Products Produced by Forced or Indentured Child Labor AGENCY: Department of Defense... acquisition of products produced by forced or indentured child labor. DATES: Submit comments on or before... on Acquisition of Products Produced by Forced or Indentured Child Labor, by any of the following...

  10. Molt salts reactors capacity for wastes incineration and energy production

    David, S.; Nuttin, A.

    2005-01-01

    The molten salt reactors present many advantages in the framework of the IV generation systems development for the energy production and/or the wastes incineration. After a recall of the main studies realized on the molten salt reactors, this document presents the new concepts and the identified research axis: the MSRE project and experience, the incinerators concepts, the thorium cycle. (A.L.B.)

  11. Enhanced production of biomass, pigments and antioxidant capacity of a nutritionally important cyanobacterium Nostochopsis lobatus.

    Pandey, Usha; Pandey, J

    2008-07-01

    A diazotrophic cyanobacterium Nostochopsis lobatus was evaluated for enhanced production of biomass, pigments and antioxidant capacity. N. lobatus showed potentially high antioxidant capacity (46.12 microM AEAC) with significant improvement under immobilized cell cultures (87.05 microM AEAC). When a mixture of P and Fe was supplemented, biomass, pigments, nutritive value and antioxidant capacity increased substantially at pH 7.8. When considered separately, P appeared to be a better supplement than Fe for the production of biomass, chlorophyll and carotenoids. However, for phycocyanin, phycoerythrin, nutritive value and antioxidant capacity, Fe appeared more effective than P. Our study indicates N. lobatus to be a promising bioresource for enhanced production of nutritionally rich biomass, pigments and antioxidants. The study also suggests that P and Fe are potentially effective supplements for scale-up production for commercial application.

  12. Countering Transnational Organized Crime: How Special Forces Build National Police Capacity in Latin America

    2015-05-01

    of Bolivia’s economy at the time.77 In addition to political instability, a weak economy, and cultural ties to coca, Bolivia faced the geographic...This research encompasses three cases in which US Special Forces partnered with national police units to achieve this objective: Bolivia , Colombia...

  13. Capacity of a quantum memory channel correlated by matrix product states

    Mulherkar, Jaideep; Sunitha, V.

    2018-04-01

    We study the capacity of a quantum channel where channel acts like controlled phase gate with the control being provided by a one-dimensional quantum spin chain environment. Due to the correlations in the spin chain, we get a quantum channel with memory. We derive formulas for the quantum capacity of this channel when the spin state is a matrix product state. Particularly, we derive exact formulas for the capacity of the quantum memory channel when the environment state is the ground state of the AKLT model and the Majumdar-Ghosh model. We find that the behavior of the capacity for the range of the parameters is analytic.

  14. Estimating product-to-product variations in metal forming using force measurements

    Havinga, Jos; van den Boogaard, Ton

    2017-10-01

    The limits of production accuracy of metal forming processes can be stretched by the development of control systems for compensation of product-to-product variations. Such systems require the use of measurements from each semi-finished product. These measurements must be used to estimate the final quality of each product. We propose to predict part of the product-to-product variations in multi-stage forming processes based on force measurements from previous process stages. The reasoning is that final product properties as well as process forces are expected to be correlated since they are both affected by material and process variation. In this study, an approach to construct a moving window process model based on historical data from the process is presented. These regression models can be built and updated in real-time during production. The approach is tested with data from a demonstrator process with cutting, deep drawing and bending stages. It is shown that part of the product-to-product variations in the process can be predicted with the developed process model.

  15. Investment in the capacity of production in a simulate environment

    Bruno Hartmut Kopittke

    2007-10-01

    Full Text Available With the objective of contributing with the theory about performance, strategic administration and business games, this study presents an evaluation and innovation approach of the GI-Logística business games. Initially, it is made a presentation of the business games, indicating your characteristic principal, objectives and conduction of the elements for take of decision with focus in the investments in the working production. The second section approaches the administration methodology and evaluation of performance of Balanced Scorecard, with emphasis in the processes of operations. The tool Balanced Scorecard will be described to be used as mark for the updatings in the GI-Logística business games. Finally, they are suggested alterations in the GI-Logística business games, as well as the due alterations in your didactic material of support.

  16. Determining the production capacity of train transportation for overburden removal

    Knahl, G; Szabados, L; Nowotny, A

    1980-02-01

    Details of two computer programs developed at the Institute of Energetics in Leipzig, GDR for use on large BESM-6 computer of the Institute are provided. One is the so-called time funds program concentrating on coal and overburden output, production time requirements and time losses. The other is a simulation program for overburden removal by train. It includes 14 pieces of heavy mining equipment, six industrial consumers and a rail network with 80 connections and 40 trains. The program was used with success in 1979 and will be further developed. Additional utilization is seen in projecting transportation in new surface mines, optimizing rail transport in existing mines for the preparation of annual train transportation plans. (In German)

  17. Ergonomics strategies and actions for achieving productive use of an ageing work-force.

    Kumashiro, M

    2000-07-01

    In this report, a basic ERGOMA (Ergonomics in Industrial Management) strategy is proposed as a policy for corporate production and employment in countries where ageing populations and reduced birth rates are imminent, and a strategy related to this is proposed. Specifically, as a strategy at the company level, the results of survey studies aimed at the development of methods for determining job capacity, to enable effective use of the labour of ageing workers, were summarized. A number of the insights gained here are steps in the development of a foundational methodology for practical use, and in actual practice a number of these insights must be subjected to measurements. However, the theory and newly developed methodology described here are thought to represent significant changes from the approaches to job capacity diagnosis and assessment published in the past and from the stance towards utilization of an ageing work-force. The author is confident that this represents new progress in one of the ergonomics approach to dealing with the working environment of ageing workers and an ageing work-force in general.

  18. Product Evaluation Task Force Phase Two report for centrifuge cake

    Francis, A.J.; Davies, A.

    1990-01-01

    It has been proposed that all Intermediate Level Wastes arising at Sellafield should be encapsulated prior to ultimate disposal. The Product Evaluation Task Force (PETF) was set up to investigate possible encapsulants and to produce and adequate data base to justify the preferred matrices. Three possible types of encapsulants for Centrifuge Cake;- Inorganic cements, Polymer cements, and Polymers, are evaluated using the Kepner Tregoe decision analysis technique. This technique provides a methodology for scoring and ranking alternative options and evaluating any risks associated with an option. The analysis shows that for all four stages of waste management operations ie. Storage Transport, handling and emplacement Disposal, and Process, cement matrices are considerably superior to other potential matrices. A matrix, consisting of nine parts Blast Furnace Slag (BFS) to one part Ordinary Portland Cement (OPC) is recommended as the preferred matrix for Phase 3 studies on Centrifuge Cake. (author)

  19. Botanical Composition, Grass Production, and Carrying Capacity of Pasture in Timor Tengah Selatan District

    V. E. Se’u

    2015-12-01

    Full Text Available This study was conducted to analyze the botanical composition, grass production, carrying capacity, and potential production of nutrients in pasture located in Timor Tengah Selatan Regency. The experiment was conducted from February to July 2013, using field survey method. The botanical composition, grass production and carrying capacity on real condition were analyzed descriptively, while the grass production and carrying capacity based of cutting arrangement were analyzed by using randomized block factorial design with 3 altitude locations (Sub District of Mollo Utara with altitude of 1007 m above sea level; Sub District of Noebeba, 500 m ASL, and Sub District of Amanuban Selatan, 65 m ASL x 2 cutting intervals (1 and 2 month and 5 replications. The results showed that the grass type dominated the pasture in the Sub District of Mollo Utara, while legum type was more dominant in the pasture in the Sub Districts of Noebeba and Amanuban Selatan. The potential production of dry matter grass in Timor Tengah Selatan Regency based on real condition was 150 to 390 kg/ha/yr, this could accommodate 0.24 to 0.63 AU/ha/yr. The arrangement of cutting interval by 1 month in Mollo Utara and 2 months in Noebeba and Amanuban Selatan could increase (P<0.05 grass production and carrying capacity. The potential productions of grass nutrients were higher in Sub District of Mollo Utara, while potential production of grass dry matter was higher in Sub Districts of Noebeba and Amanuban Selatan. It was concluded that grass dry matter potential production and carrying capacity in Timor Tengah Selatan Regency were low. The arrangement of cutting interval could increase grass dry matter potential production, carrying capacity, nutrition production, and quality of nutrition.

  20. Challenges facing the financing of oil production capacity in the Gulf

    Abi-Aad, Naji.

    1995-01-01

    The estimates of the required capital for maintaining and expanding oil production capacity in the 'Big Five' producers in the Gulf (Iran, Iraq, Kuwait, Saudi Arabia and the United Emirates) are large numbers. In fact, looking at the total cost of raising the Gulf oil production capacity from 18.5 million b/d in 1990 to 26.8 million b/d in the year 2005, the eventual sum is likely to end up at around $192 billion (1990 $) of which about $150 billion will be required as normal investment to maintain current output levels, and a further $42 billion will be necessary to develop new capacities. In short, the Gulf countries will need to spend an average of $12-13 billion per year to maintain current production and to raise some 8.3 million b/d of new capacity by 2005. (author)

  1. Modelling ramp-up curves to reflect learning: improving capacity planning in secondary pharmaceutical production

    Hansen, Klaus Reinholdt Nyhuus; Grunow, Martin

    2015-01-01

    availability at market launch is ensured. Our MILP model is applied to a real industry case study using three empirically observed ramp-up curves to demonstrate its value as decision support tool. We demonstrate the superiority of our volume-dependent method over the traditional time-dependent ramp......The experience gained during production ramp-up leads to an increase of the effective production capacity over time. However, full utilisation of production capacity is not always possible during ramp-up. In such cases, the experience gained and hence the available effective capacity...... are overestimated. We develop a new method, which captures ramp-up as a function of the cumulative production volume to better reflect the experience gained while producing the new product. The use of the more accurate and computationally effective approach is demonstrated for the case of secondary pharmaceutical...

  2. Experience of research, design, capacity, and operation with forced flow steam generators

    Bertolotti, G.; McDonald, B.N.; Pocock, F.J.

    1975-01-01

    The forced flow steam generators in operation in six American nuclear power plants show an excellent operational behaviour. The concept for this type of steam generator has been developed in the USA, and it has been successfully tested over several years regarding its suitability for PWRs of a larger size. The results concerning construction, materials and water chemistry for this steam generator, which will be used for the first time in the FRG in the nuclear power station Muelheim-Kaerlich, have confirmed the high reliability of this high-efficiency component. (orig./LN) [de

  3. Improving nuclear utility generation capacity, understanding the sources of forced outage and learning how to prevent them

    Brodeur, D.L.; Todreas, N.E.; Angus, V.T.

    1998-01-01

    MIT and PECO Energy have completed a detailed examination of the sources of forced outages at the Limerick Generating Station (LGS) Boiling Water Reactor Class IV (BWR IV) site over a five year period and contrasted that information to similar BWR IV utilities in the United States over the same period. Each forced outage was attributed to one system and assigned causal codes of equipment versus human factors and failure attributes such as weak design, poor craftsmanship, and worn parts. It was found that fifty four percent of the lost power at LGS was the result of Balance of Plant failures. Industry wide data identifies fifty nine percent of the lost power as attributed to Balance of Plant failures. Balance of Plant systems are those systems not included in the primary and safety related system category. Considering failure causal factors, forty six percent of the lost power at the utility under study was the result of equipment factors such as weak design or worn parts. Significantly, the study showed a high variance between those systems which caused significant forced outage at the two sister LGS units. This demonstrated the infrequent nature of plant forced outages within a given system. This was supported by the observation that dominant systems attributing to forced outage at LGS were not equally represented in industry data. It is suggested that for individual utilities to dramatically improve unit capability factors with regard to Balance of Plant systems, they must learn from industry wide experiences and develop cooperative means of exchanging lessons learned among similarly designed plants and systems. With the broad knowledge base of system failures, current designs must be frequently assessed and altered until each system poses an acceptable level of risk to generation capacity. (author)

  4. Verifying Air Force Weather Passive Satellite Derived Cloud Analysis Products

    Nobis, T. E.

    2017-12-01

    Air Force Weather (AFW) has developed an hourly World-Wide Merged Cloud Analysis (WWMCA) using imager data from 16 geostationary and polar-orbiting satellites. The analysis product contains information on cloud fraction, height, type and various optical properties including optical depth and integrated water path. All of these products are derived using a suite of algorithms which rely exclusively on passively sensed data from short, mid and long wave imager data. The system integrates satellites with a wide-range of capabilities, from the relatively simple two-channel OLS imager to the 16 channel ABI/AHI to create a seamless global analysis in real time. Over the last couple of years, AFW has started utilizing independent verification data from active sensed cloud measurements to better understand the performance limitations of the WWMCA. Sources utilized include space based lidars (CALIPSO, CATS) and radar (CloudSat) as well as ground based lidars from the Department of Energy ARM sites and several European cloud radars. This work will present findings from our efforts to compare active and passive sensed cloud information including comparison techniques/limitations as well as performance of the passive derived cloud information against the active.

  5. Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.

    Gumucio, Jonathan P; Davis, Max E; Bradley, Joshua R; Stafford, Patrick L; Schiffman, Corey J; Lynch, Evan B; Claflin, Dennis R; Bedi, Asheesh; Mendias, Christopher L

    2012-12-01

    Full-thickness tears to the rotator cuff can cause severe pain and disability. Untreated tears progress in size and are associated with muscle atrophy and an infiltration of fat to the area, a condition known as "fatty degeneration." To improve the treatment of rotator cuff tears, a greater understanding of the changes in the contractile properties of muscle fibers and the molecular regulation of fatty degeneration is essential. Using a rat model of rotator cuff injury, we measured the force generating capacity of individual muscle fibers and determined changes in muscle fiber type distribution that develop after a full thickness rotator cuff tear. We also measured the expression of mRNA and miRNA transcripts involved in muscle atrophy, lipid accumulation, and matrix synthesis. We hypothesized that a decrease in specific force of rotator cuff muscle fibers, an accumulation of type IIb fibers, and an upregulation in fibrogenic, adipogenic, and inflammatory gene expression occur in torn rotator cuff muscles. Thirty days following rotator cuff tear, we observed a reduction in muscle fiber force production, an induction of fibrogenic, adipogenic, and autophagocytic mRNA and miRNA molecules, and a dramatic accumulation of macrophages in areas of fat accumulation. Copyright © 2012 Orthopaedic Research Society.

  6. No Neuromuscular Side-Effects of Scopolamine in Sensorimotor Control and Force-Generating Capacity Among Parabolic Fliers

    Ritzmann, Ramona; Freyler, Kathrin; Krause, Anne; Gollhofer, Albert

    2016-10-01

    Scopolamine is used to counteract motion sickness in parabolic flight (PF) experiments. Although the drug's anticholinergic properties effectively impede vomiting, recent studies document other sensory side-effects in the central nervous system that may considerably influence sensorimotor performance. This study aimed to quantify such effects in order to determine if they are of methodological and operational significance for sensorimotor control. Ten subjects of a PF campaign received a weight-sex-based dose of a subcutaneous scopolamine injection. Sensorimotor performance was recorded before medication, 20min, 2h and 4h after injection in four space-relevant paradigms: balance control in one-leg stance with eyes open (protocol 1) and closed as well as force-generating capacity in countermovement jumps and hops (protocol 2). Postural sway, forces and joint angles were recorded. Neuromuscular control was assessed by electromyography and peripheral nerve stimulation; H-reflexes and M-waves were used to monitor spinal excitability of the Ia afferent reflex circuitry and maximal motor output. (1) H-reflex amplitudes, latencies and functional reflexes remained unchanged after scopolamine injection. (2) M-waves, neuromuscular activation intensities and antagonistic muscle coordination did not change with scopolamine administration. (3) Balance performance and force-generating capacity were not impeded by scopolamine. We found no evidence for changes in sensorimotor control in response to scopolamine injection. Sensory processing of daily relevant reflexes, spinal excitability, maximal motor output and performance parameters were not sensitive to the medication. We conclude that scopolamine administration can be used to counteract motion sickness in PF without methodological and operational concerns or interference regarding sensorimotor skills associated with neuromuscular control.

  7. 12 CFR 7.5004 - Sale of excess electronic capacity and by-products.

    2010-01-01

    ... bank's needs for banking purposes include: (1) Data processing services; (2) Production and... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Sale of excess electronic capacity and by-products. 7.5004 Section 7.5004 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY...

  8. Production capacity of equipment for medium and large hydroelectric power plant in China

    Huang Shenyang [Ministry of Electric Power, Beijing (China). Bureau of Electric Power Machinery

    1995-07-01

    This document presents an overview on the production capacity of equipment for medium and large hydroelectric power plant in China. The document approaches general aspects, production capability and testing facilities related to Francis, Kaplan, tubular and impulse hydroelectric generating sets, and the introduction of main manufacturers as well.

  9. Polynomial Time Algorithms For Some Multi-Level Lot-Sizing Problems With Production Capacities

    S. van Hoesel (Stan); H.E. Romeijn (Edwin); D. Romero Morales (Dolores); A.P.M. Wagelmans (Albert)

    2002-01-01

    textabstractWe consider a model for a serial supply chain in which production, inventory, and transportation decisions are integrated, in the presence of production capacities and for different transportation cost functions. The model we study is a generalization of the traditional single-item

  10. Assessing refinery capacity and readiness to take Canadian product : is Canadian crude pushing or pulling?

    Friesner, J.M.

    2005-01-01

    This presentation addressed some of the challenges facing oil sands production in Canada. Refinery products and refining investments were discussed, as was the impact of alternative crude supply on the markets and pricing of oil sands. The oils sands products discussed include various qualities of sweet synthetic crude oil produced via upgraders; virgin and cracked intermediate products from oil sands upgraders; mined or Steam Assisted Gravity Drainage (SAGD) produced bitumen blended products; and synthetic heavy crude produced via hydrocracking. Products were listed in terms of ease of production, and a rationale for generic ranking was provided. A chart of 2003 characteristics of non-Canadian imports to the mid-west United States was provided. Various marketing strategies for different oil sands products were discussed, as well as issues concerning logistics. Strategies for the development of a bigger market include producer investment in refining capability; the acquisition of refining assets; investment in refiners' upgrading capability; and securing a long term supply deal. Core and extended markets for Western Canadian oil sands products were reviewed. A chart of North American refining capacity was presented. Details of a refinery with both coking and cracking capacity were examined. An increase in hydro processing capacity and expanded coking capacity, as well as an upgrade of metallurgy were suggested as possible upgrading options. Various refinery configurations were discussed in relation to lower cost feedstocks and clean fuels specifications. Issues concerning crude supply were examined with reference to pricing parity points and declines in traditional crude production. Specific supply issues concerning oil sands production were discussed, including transportation costs; adequate refining capacity; and availability of supply. Various logistic investments were considered. A map of BP's 5 U.S. refineries was presented. A forecast of expected changes in

  11. Portfolio theory of optimal isometric force production: Variability predictions and nonequilibrium fluctuation dissipation theorem

    Frank, T. D.; Patanarapeelert, K.; Beek, P. J.

    2008-05-01

    We derive a fundamental relationship between the mean and the variability of isometric force. The relationship arises from an optimal collection of active motor units such that the force variability assumes a minimum (optimal isometric force). The relationship is shown to be independent of the explicit motor unit properties and of the dynamical features of isometric force production. A constant coefficient of variation in the asymptotic regime and a nonequilibrium fluctuation-dissipation theorem for optimal isometric force are predicted.

  12. Portfolio theory of optimal isometric force production: Variability predictions and nonequilibrium fluctuation-dissipation theorem

    Frank, T.D.; Patanarapeelert, K.; Beek, P.J.

    2008-01-01

    We derive a fundamental relationship between the mean and the variability of isometric force. The relationship arises from an optimal collection of active motor units such that the force variability assumes a minimum (optimal isometric force). The relationship is shown to be independent of the explicit motor unit properties and of the dynamical features of isometric force production. A constant coefficient of variation in the asymptotic regime and a nonequilibrium fluctuation-dissipation theorem for optimal isometric force are predicted

  13. A Method of Flow-Shop Re-Scheduling Dealing with Variation of Productive Capacity

    Kenzo KURIHARA

    2005-02-01

    Full Text Available We can make optimum scheduling results using various methods that are proposed by many researchers. However, it is very difficult to process the works on time without delaying the schedule. There are two major causes that disturb the planned optimum schedules; they are (1the variation of productive capacity, and (2the variation of products' quantities themselves. In this paper, we deal with the former variation, or productive capacities, at flow-shop works. When production machines in a shop go out of order at flow-shops, we cannot continue to operate the productions and we have to stop the production line. To the contrary, we can continue to operate the shops even if some workers absent themselves. Of course, in this case, the production capacities become lower, because workers need to move from a machine to another to overcome the shortage of workers and some shops cannot be operated because of the worker shortage. We developed a new re-scheduling method based on Branch-and Bound method. We proposed an equation for calculating the lower bound for our Branch-and Bound method in a practical time. Some evaluation experiments are done using practical data of real flow-shop works. We compared our results with those of another simple scheduling method, and we confirmed the total production time of our result is shorter than that of another method by 4%.

  14. A simple method for assessment of muscle force, velocity, and power producing capacities from functional movement tasks.

    Zivkovic, Milena Z; Djuric, Sasa; Cuk, Ivan; Suzovic, Dejan; Jaric, Slobodan

    2017-07-01

    A range of force (F) and velocity (V) data obtained from functional movement tasks (e.g., running, jumping, throwing, lifting, cycling) performed under variety of external loads have typically revealed strong and approximately linear F-V relationships. The regression model parameters reveal the maximum F (F-intercept), V (V-intercept), and power (P) producing capacities of the tested muscles. The aim of the present study was to evaluate the level of agreement between the routinely used "multiple-load model" and a simple "two-load model" based on direct assessment of the F-V relationship from only 2 external loads applied. Twelve participants were tested on the maximum performance vertical jumps, cycling, bench press throws, and bench pull performed against a variety of different loads. All 4 tested tasks revealed both exceptionally strong relationships between the parameters of the 2 models (median R = 0.98) and a lack of meaningful differences between their magnitudes (fixed bias below 3.4%). Therefore, addition of another load to the standard tests of various functional tasks typically conducted under a single set of mechanical conditions could allow for the assessment of the muscle mechanical properties such as the muscle F, V, and P producing capacities.

  15. Procedures to determine the guaranteed production capacity of a heavy water plant

    Peculea, Marius

    1999-01-01

    The capacity of a heavy water plant is determined by its design and represents a product between the plant production/hour and the running time. The production/hour is calculated for steady state conditions and the running time is estimated by the designer. Actually, the isotopic separation process takes place in unsteady state conditions and the working time is affected by equipment failure or even damages, after which a relaxation time is necessary for isotopic profile recovery along the separation columns. To determine the actual capacity, the designed capacity is corrected by the product of three coefficients: availability, reliability, and relaxation. The knowledge of the above mentioned coefficients allows the determination of the actual plant capacity; this is important also for further improvements of the separation technology and represents research objectives during the whole existence of such a plant in order to maintain it at an international level of competitiveness. The detailed content of the three coefficients and the way they were determined and experimentally verified on an industrial pilot plant for heavy water production by isotopic exchange at two temperatures in H 2 O - H 2 S system, are presented in this paper. (author)

  16. Utilizing Forced Vital Capacity to Predict Low Lung Compliance and Select Intraoperative Tidal Volume During Thoracic Surgery.

    Hoftman, Nir; Eikermann, Eric; Shin, John; Buckley, Jack; Navab, Kaveh; Abtin, Fereidoun; Grogan, Tristan; Cannesson, Maxime; Mahajan, Aman

    2017-12-01

    Tidal volume selection during mechanical ventilation utilizes dogmatic formulas that only consider a patient's predicted body weight (PBW). In this study, we investigate whether forced vital capacity (FVC) (1) correlates better to total lung capacity (TLC) than PBW, (2) predicts low pulmonary compliance, and (3) provides an alternative method for tidal volume selection. One hundred thirty thoracic surgery patients had their preoperative TLC calculated via 2 methods: (1) pulmonary function test (PFT; TLCPFT) and (2) computed tomography 3D reconstruction (TLCCT). We compared the correlation between TLC and PBW with the correlation between TLC and FVC to determine which was stronger. Dynamic pulmonary compliance was then calculated from intraoperative ventilator data and logistic regression models constructed to determine which clinical measure best predicted low compliance. Ratios of tidal volume/FVC plotted against peak inspiratory pressure were utilized to construct a new model for tidal volume selection. Calculated tidal volumes generated by this model were then compared with those generated by the standard lung-protective formula Vt = 7 cc/kg. The correlation between FVC and TLC (0.82 for TLCPFT and 0.76 for TLCCT) was stronger than the correlation between PBW and TLC (0.65 for TLCPFT and 0.58 for TLCCT). Patients with very low compliance had significantly smaller lung volumes (forced expiratory volume at 1 second, FVC, TLC) and lower diffusion capacity of the lungs for carbon monoxide when compared with patients with normal compliance. An FVC cutoff of 3470 cc was 100% sensitive and 51% specific for predicting low compliance. The proposed equation Vt = FVC/8 significantly reduced calculated tidal volume by a mean of 22.5% in patients with low pulmonary compliance without affecting the mean tidal volume in patients with normal compliance (mean difference 0.9%). FVC is more strongly correlated to TLC than PBW and a cutoff of about 3.5 L can be utilized to predict

  17. Developing a Personnel Capacity Indicator for a high turnover Cartographic Production Sector

    Mandarino, Flávia; Pessôa, Leonardo A. M.

    2018-05-01

    This paper describes a framework for development of an indicator for human re-sources capacity management in a military organization responsible for nautical chart production. Graphic chart for the results of the model COPPE-COSENZA (Cosenza et al. 2015) is used to properly present the personnel capacity within a high people turnover environment. The specific skills for the nautical charts production allied to the turnover rate require continuous and adequate personnel in-corporation and a capacity building through education and on-the-job training. The adopted approach for the study establishes quantitative values to fulfill quality requirements, and also presents graphically a profile for the human resources on a specific job to facilitate diagnosis and corrective actions.

  18. Natural gas productive capacity for the lower 48 states 1984 through 1996, February 1996

    1996-01-01

    This is the fourth wellhead productive capacity report. The three previous ones were published in 1991, 1993, and 1994. This report should be of particular interest to those in Congress, Federal and State agencies, industry, and the academic community, who are concerned with the future availability of natural gas. The EIA Dallas Field Office has prepared five earlier reports regarding natural gas productive capacity. These reports, Gas Deliverability and Flow Capacity of Surveillance Fields, reported deliverability and capacity data for selected gas fields in major gas producing areas. The data in the reports were based on gas-well back-pressure tests and estimates of gas-in-place for each field or reservoir. These reports use proven well testing theory, most of which has been employed by industry since 1936 when the Bureau of Mines first published Monograph 7. Demand for natural gas in the United States is met by a combination of natural gas production, underground gas storage, imported gas, and supplemental gaseous fuels. Natural gas production requirements in the lower 48 States have been increasing during the last few years while drilling has remained at low levels. This has raised some concern about the adequacy of future gas supplies, especially in periods of peak heating or cooling demand. The purpose of this report is to address these concerns by presenting a 3-year projection of the total productive capacity of natural gas at the wellhead for the lower 48 States. Alaska is excluded because Alaskan gas does not enter the lower-48 States pipeline system. The Energy Information Administration (EIA) generates this 3-year projection based on historical gas-well drilling and production data from State, Federal, and private sources. In addition to conventional gas-well gas, coalbed gas and oil-well gas are also included

  19. Production capacity of metallurgical enterprises in modular structure of management accounting

    Zambrzhitskaia E.S.

    2017-01-01

    Full Text Available This article is the result of constant research in development of management accounting at modern Russian metallurgical works. The required steps of renovation are presented for the modernization of management accounting system in the case of production capacity. The necessary factors with defined values are systematized for modern enterprises. The main ones are those which are regulate the measure of the payload of production capacity. For the purposes of effective management accounting at metallurgical enterprises it is suggested to use the system of controlling parameters which were formulated for the enterprise for production of rolls. Later in the article the necessary changes to the modular structure of management accounting business are described and expanded with new structural element – “Management of production capacity”. The suggested methodical approach will allow the company management to respond quickly to rapidly changing external environment and, as a consequence, to make effective management decisions.

  20. Capacity building improve Malaysia's inspection and monitoring system for aquaculture and fishery products

    Gevers, G.J.M.; Zoontjes, P.W.; Essers, M.L.; Klijnstra, M.; Gerssen, A.

    2012-01-01

    The project aimed to help build a credible inspection and monitoring system that can guarantee safe quality products of Ministry of Health (MoH) and Department of Fisheries (DoF) by upgrading the analytical capacity of the laboratory staff directly involved in the analysis and detection of forbidden

  1. The petrochemical production capacity of the Saudi Arabian Basic Industry Corporation (SABIC)

    Anon.

    1993-01-01

    This paper describes the development program of the SABIC (Saudi Arabian Basic Industry Co.) which has provided the building of new petrochemical units while retrofitting old units or developing the capacities of some of them. Statistical data on petrochemical production, sales and exports, contracts and joint ventures are also given. 2 tabs

  2. Immunomodulatory capacity of fungal proteins on the cytokine production of human peripheral blood mononuclear cells

    Jeurink, P.V.; Lull Noguera, C.; Savelkoul, H.F.J.; Wichers, H.J.

    2008-01-01

    Immunomodulation by fungal compounds can be determined by the capacity of the compounds to influence the cytokine production by human peripheral blood mononuclear cells (hPBMC). These activities include mitogenicity, stimulation and activation of immune effector cells. Eight mushroom strains

  3. RDT&E Laboratory Capacity Utilization and Productivity Measurement Methods for Financial Decision-Making within DON

    Haupt, Jeffrey

    1998-01-01

    .... Industry capacity utilization and productivity measurement techniques and models were evaluated for their potential application to the Naval Air Warfare Center Aircraft Division (NAWCAD) RDT&E organization...

  4. Uranium from Coal Ash: Resource Assessment and Outlook on Production Capacities

    Monnet, Antoine

    2014-01-01

    Conclusion: Uranium production from coal-ash is technically feasible: in some situations, it could reach commercial development, in such case, fast lead time will be a plus. Technically accessible resources are significant (1.1 to 4.5 MtU). Yet most of those are low grade. Potential reserves don’t exceed 200 ktU (cut-off grade = 200 ppm). • By-product uranium production => constrained production capacities; • Realistic production potential < 700 tU/year; • ~ 1% of current needs. → Coal ash will not be a significant source of uranium for the 21st century – even if production constrains are released (increase in coal consumption

  5. Absorptive Capacity and Innovation: An Overview of International Scientific Production of Last Twenty-Five Years

    Dennys Eduardo Rossetto

    2017-02-01

    Full Text Available This work aims to achieve an overview of international scientific production on absorptive and innovation capacities in order to mapping the academic contributions already made between 1990 and 2015 (last 25 years. Bibliometric methods, and social network analysis were used to understand the behavior of 1,693 published articles and analysis of key works cited. Most notably, the growing publication with related topics, in approximate exponential growth, concentration of work into five groups and six cocitação periodic coupling groups, indicating possible fields for publication related to the themes absorptive capacity and innovation. The analysis of the key articles cited identifies the themes and methods used, as well as understand the context of the themes absorptive capacity and innovation.

  6. Forced vital capacity and not central chemoreflex predicts maximal hyperoxic breath-hold duration in elite apneists.

    Bain, Anthony R; Barak, Otto F; Hoiland, Ryan L; Drvis, Ivan; Bailey, Damian M; Dujic, Zeljko; Mijacika, Tanja; Santoro, Antoinette; DeMasi, Daniel K; MacLeod, David B; Ainslie, Philip N

    2017-08-01

    The determining mechanisms of a maximal hyperoxic apnea duration in elite apneists have remained unexplored. We tested the hypothesis that maximal hyperoxic apnea duration in elite apneists is related to forced vital capacity (FVC) but not the central chemoreflex (for CO 2 ). Eleven elite apneists performed a maximal dry static-apnea with prior hyperoxic (100% oxygen) pre-breathing, and a central chemoreflex test via a hyperoxic re-breathing technique (hyperoxic-hypercapnic ventilatory response: HCVR); expressed as the increase in ventilation (pneumotachometry) per increase in arterial CO 2 tension (PaCO 2 ; radial artery). FVC was assessed using standard spirometry. Maximal apnea duration ranged from 807 to 1262s (mean=1034s). Average HCVR was 2.0±1.2Lmin -1 mmHg -1 PaCO 2 . The hyperoxic apnea duration was related to the FVC (r 2 =0.45, p0.05). These findings were interpreted to suggest that during a hyperoxic apnea, a larger initial lung volume prolongs the time before reaching intolerable discomfort associated with pending lung squeeze, while CO 2 sensitivity has little impact. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Crash worthy capacity of a hybridized epoxy-glass fiber aluminum columnar tube using repeated axial resistive force

    Paruka, Perowansa [Jalan Politeknik, Kota Kinabalu (Malaysia); Siswanto, Waluyo Adi [Universiti Tun Hussein Onn Malaysia, Parit Raja (Malaysia); Maleque, Md Abdul [Universiti Islam Antarabangsa Malaysia, Kuala Lumpur (Malaysia); Shah, Mohd Kamal Mohd [Universiti Malaysia Sabah, Kota Kinabalu (Malaysia)

    2015-05-15

    A combination of aluminum columnar member with composite laminate to form a hybrid structure can be used as collapsible energy absorbers especially in automotive vehicular structures to protect occupants and cargo. A key advantage of aluminum member in composite is that it provides ductile and stable plastic collapse mechanisms with progressive deformation in a stable manner by increasing energy absorption during collision. This paper presents an experimental investigation on the influence of the number of hybrid epoxy glass layers in overwrap composite columnar tubes. Three columnar tube specimens were used and fabricated by hand lay-up method. Aluminum square hollow shape was combined with externally wrapped by using an isophthalic epoxy resin reinforced with glass fiber skin with an orientation angle of 0 .deg. /90 .deg. The aluminum columnar tube was used as reference material. Crushed hybrid-composite columnar tubes were prepared using one, two, and three layers to determine the crash worthy capacity. Quasi-static crush test was conducted using INSTRON machine with an axial loading. Results showed that crush force and the number of layers were related to the enhancement of energy absorption before the collapse of columnar tubes. The energy absorption properties of the crushed hybrid-composite columnar tubes improved significantly with the addition of layers in the overwrap. Microscopic analysis on the modes of epoxy-glass fiber laminate failure was conducted by using scanning electron microscopy.

  8. Critical force during tethered swimming for the evaluation of aerobic capacity and prediction of performances in freestyle swimming

    Marcelo Papoti

    2010-01-01

    Full Text Available The present study investigated the relationship of critical force (Fcrit with lactate threshold (LLNA and the intensity corresponding to VO2max (iVO2max in tethered swimming (TS, and their correlation with maximal performance in 400-m (V400 and 30-min (VT30 freestyle swimming (FS. Seven swimmers were submitted to a TS incremental test for the determination of LLNA and iVO2max. For the determination of Fcrit, the swimmers performed four exercises to exhaustion at intensities (F corresponding to 87%, 104%, 118% and 134% of iVO2max for the calculation of time limits (Tlim. Fcrit corresponded to the linear coefficient of the ratio between F and 1/tlim. The maximal performance in FS corresponded to the mean velocity obtained during maximal exercise of 400-m and 30-min crawl swimming. Fcrit (51.97 ± 4.02 N was significantly lower than iVO2max (60.21 ± 8.73 N but not than LLNA (45.89 ± 8.73. Fcrit was significantly correlated with iVO2max (0.97, LLNA (0.88, V400 (0.85, and VT30 (0.86. These data suggest that Fcrit can be used for the determination of aerobic capacity, prescription of a TS training program, and prediction of performance in FS.

  9. Eccentric Contraction-Induced Muscle Injury: Reproducible, Quantitative, Physiological Models to Impair Skeletal Muscle's Capacity to Generate Force.

    Call, Jarrod A; Lowe, Dawn A

    2016-01-01

    In order to investigate the molecular and cellular mechanisms of muscle regeneration an experimental injury model is required. Advantages of eccentric contraction-induced injury are that it is a controllable, reproducible, and physiologically relevant model to cause muscle injury, with injury being defined as a loss of force generating capacity. While eccentric contractions can be incorporated into conscious animal study designs such as downhill treadmill running, electrophysiological approaches to elicit eccentric contractions and examine muscle contractility, for example before and after the injurious eccentric contractions, allows researchers to circumvent common issues in determining muscle function in a conscious animal (e.g., unwillingness to participate). Herein, we describe in vitro and in vivo methods that are reliable, repeatable, and truly maximal because the muscle contractions are evoked in a controlled, quantifiable manner independent of subject motivation. Both methods can be used to initiate eccentric contraction-induced injury and are suitable for monitoring functional muscle regeneration hours to days to weeks post-injury.

  10. Crash worthy capacity of a hybridized epoxy-glass fiber aluminum columnar tube using repeated axial resistive force

    Paruka, Perowansa; Siswanto, Waluyo Adi; Maleque, Md Abdul; Shah, Mohd Kamal Mohd

    2015-01-01

    A combination of aluminum columnar member with composite laminate to form a hybrid structure can be used as collapsible energy absorbers especially in automotive vehicular structures to protect occupants and cargo. A key advantage of aluminum member in composite is that it provides ductile and stable plastic collapse mechanisms with progressive deformation in a stable manner by increasing energy absorption during collision. This paper presents an experimental investigation on the influence of the number of hybrid epoxy glass layers in overwrap composite columnar tubes. Three columnar tube specimens were used and fabricated by hand lay-up method. Aluminum square hollow shape was combined with externally wrapped by using an isophthalic epoxy resin reinforced with glass fiber skin with an orientation angle of 0 .deg. /90 .deg. The aluminum columnar tube was used as reference material. Crushed hybrid-composite columnar tubes were prepared using one, two, and three layers to determine the crash worthy capacity. Quasi-static crush test was conducted using INSTRON machine with an axial loading. Results showed that crush force and the number of layers were related to the enhancement of energy absorption before the collapse of columnar tubes. The energy absorption properties of the crushed hybrid-composite columnar tubes improved significantly with the addition of layers in the overwrap. Microscopic analysis on the modes of epoxy-glass fiber laminate failure was conducted by using scanning electron microscopy.

  11. Transportation and Production Lot-size for Sugarcane under Uncertainty of Machine Capacity

    Sudtachat Kanchala

    2018-01-01

    Full Text Available The integrated transportation and production lot size problems is important effect to total cost of operation system for sugar factories. In this research, we formulate a mathematic model that combines these two problems as two stage stochastic programming model. In the first stage, we determine the lot size of transportation problem and allocate a fixed number of vehicles to transport sugarcane to the mill factory. Moreover, we consider an uncertainty of machine (mill capacities. After machine (mill capacities realized, in the second stage we determine the production lot size and make decision to hold units of sugarcane in front of mills based on discrete random variables of machine (mill capacities. We investigate the model using a small size problem. The results show that the optimal solutions try to choose closest fields and lower holding cost per unit (at fields to transport sugarcane to mill factory. We show the results of comparison of our model and the worst case model (full capacity. The results show that our model provides better efficiency than the results of the worst case model.

  12. Maximizing Production Capacity from an Ultrafiltration Process at the Hanford Department of Waste Treatment Facility

    Foust, Henry C.; Holton, Langdon K.; Demick, Laurence E.

    2005-01-01

    The Department of Energy has contracted Bechtel National, Inc. to design, construct and commission a Waste Treatment and Immobilization Plant (WTP) to treat radioactive slurry currently stored in underground waste storage tanks. A critical element of the waste treatment capacity for the WTP is the proper operation of an ultrafiltration process (UFP). The UFP separates supernate solution from radioactive solids. The solution and solid phases are separately immobilized. An oversight review of the UFP design and operation has identified several methods to improve the capacity of the ultrafiltration process, which will also improve the capacity of the WTP. Areas explored were the basis of design, an analysis of the WTP capacity, process chemistry within the UFP, and UFP process control. This article discusses some of the findings of this oversight review in terms of sodium and solid production, which supports the treatment of low activity waste (LAW) associated with the facility, and solid production, which supports the treatment of high level waste (HLW) associated with the facility

  13. Factors affecting the water holding capacity of red meat products: a review of recent research advances.

    Cheng, Qiaofen; Sun, Da-Wen

    2008-02-01

    The water holding capacity of meat products is a very important quality attribute which has an influence on product yield, which in turn has economic implications, but is also important in terms of eating quality. A number of pre-and post-mortem factors influence the water holding capacity (WHC) of meat. During the growth and development of meat animals, genotype and animal diet are important due to their direct influence on muscle characteristics. In the immediate pre-slaughter period, stresses on the animal such as fasting, and different stunning methods are likely to influence meat WHC. In the post-slaughter period chilling, ageing, injecting non-meat ingredients, as well as tumbling have important influences on WHC. Furthermore, cooking and cooling procedures for the final meat products can also affect the WHC of the product, in particular the cooking and the cooling methods, the heating and the cooling rate, the cooking temperature, and the endpoint temperature. This paper provides an overview of recent research on important intrinsic and extrinsic factors that affect the WHC of beef, pork, and lamb products, and reveals explanations and solutions to some of the critical problems related to WHC and product quality.

  14. Evaluation of empowerment program to increase production capacity of fishery processing business in Semarang City, Indonesia

    Swastawati, F.; Roessali, W.; Wijayanti, I.; Anggo, A. D.

    2018-01-01

    This study aims to evaluate the empowerment program to increase the production capacity of fishery product processing. Empowerment program was the implementation and utilization of science and technology in the area (IPTEKDA) LIPI Indonesia for Higher Education. Activity carried out in 2016 on fish processing industry “Lumintu Group”. Implementation of activities includes the transfer of technology to increase production capacity, business capital assistance in the form of production equipment, production assistance, and business management. This study uses qualitative, descriptive analysis, data collection with observation, interviews, and questionnaires. The results showed that the total number of active members was 24 people, 50% of the members specially cultivated the smoked fish that is the type of Catfish (Arius thalassinus) and Stingray (Dasyatis sp), while 45.83% of members processed boneless milkfish, and 4,17% produce salted fish. Increased average production scale of 31.82% in smoked fish business, 12.4% in boneless milkfish and 38.89% in salted fish business. Willingness to return capital in the good category, meaning that all members were able to carry out the schedule of relative payback on time. Approximately 83.3% of the group members felt that the program that followed had greatly assisted in increasing the scale of business but hoped to improve skills in terms of processing and marketing.

  15. Multiple energy supply risks, optimal reserves, and optimal domestic production capacities

    Zweifel, P.; Ferrari, M.

    1992-01-01

    This study starts from the observation that today's Western trading nations are exposed to multiple risks of energy supplies, e.g. simultaneous shortage of oil and electricity supplies. To cope with these risks, oil can be stockpiled as well as domestic capacity for power production built up. Adopting the viewpoint of a policy maker who aims at minimizing the expected cost of security of supply, optimal simultaneous adjustments of oil stocks and electric production capacities to exogenous changes such as economic growth are derived. Against this benchmark, one-dimensional rules such as 'oil reserves for 90 days' turn out to be not only suboptimal but also to foster adjustments that exacerbate suboptimality. 9 refs., 1 tabs

  16. Influence of capacity- and time-constrained intermediate storage in two-stage food production systems

    Akkerman, Renzo; van Donk, Dirk Pieter; Gaalman, Gerard

    2007-01-01

    In food processing, two-stage production systems with a batch processor in the first stage and packaging lines in the second stage are common and mostly separated by capacity- and time-constrained intermediate storage. This combination of constraints is common in practice, but the literature hardly...... of systems like this. Contrary to the common sense in operations management, the LPT rule is able to maximize the total production volume per day. Furthermore, we show that adding one tank has considerable effects. Finally, we conclude that the optimal setup frequency for batches in the first stage...... pays any attention to this. In this paper, we show how various capacity and time constraints influence the performance of a specific two-stage system. We study the effects of several basic scheduling and sequencing rules in the presence of these constraints in order to learn the characteristics...

  17. Urban food crop production capacity and competition with the urban forest

    Jeffrey J Richardson; L. Monika Moskal

    2016-01-01

    The sourcing of food plays a significant role in assessing the sustainability of a city, but it is unclear how much food a city can produce within its city limits. In this study, we propose a method for estimating the maximum food crop production capacity of a city and demonstrate the method in Seattle, WA USA by taking into account land use, the light environment, and...

  18. Stability measures for rolling schedules with applications to capacity expansion planning, master production scheduling, and lot sizing

    Kimms, Alf

    1996-01-01

    This contribution discusses the measurement of (in-)stability of finite horizon production planning when done on a rolling horizon basis. As examples we review strategic capacity expansion planning, tactical master production schedulng, and operational capacitated lot sizing.

  19. Research on the Decision Model for Self-Production and Outsourcing Choices under Limited Production Capacity

    Y.-T. Chang; C.-Y. Lo

    2011-01-01

    Problem statement: In the face of competitive environments with uncertain demands and a trend toward High-Mix, Low-Volume (HMLV) production, self-production or direct outsourcing has troubled decision-makers of enterprise for a long time. In the previous studies, not much has been written about the topic. Approach: Therefore, this study applies the Analytic Hierarchy Process (AHP) to investigate the topic through either qualitative or quantitative decision-making factors that influence enterp...

  20. Implementation plan for the new production reactor capacity environmental impact statement

    1989-12-01

    The US Department of Energy (DOE) proposed to site, construct, and operate new production reactor (NPR) capacity intended primarily to produce tritium and secondarily to produce plutonium for the US nuclear weapons program. DOE studies show that this new capacity is needed to ensure reliable maintenance of the nation's nuclear weapons stockpile. It also is essential that these necessary nuclear materials be produced in a safe and environmentally sound manner. The DOE has determined that this proposed action constitutes a major federal action that may significantly affect the quality of the human environment; therefore, the DOE will prepare an environmental impact statement (EIS) to assess the potential impacts of the proposed action and reasonable alternatives on the human and natural environment. The EIS will be prepared in accordance with the National Environmental Policy Act of 1969, as implemented in regulations promulgated by the Council on Environmental Quality (CEQ). This EIS implementation plan (IP) includes a description of the proposed action, descriptions of alternatives, a summary of EIS assumptions, a list of environmental issues to be considered in the EIS (including those identified during public scoping activities), a list of proposed agency consultations, a schedule for EIS preparation and related activities, and an annotated outline for the EIS. It is the Department's intent that the EIS on the NPR capacity will serve as the programmatic National Environmental Policy Act (NEPA) review of modernization of DOE defense nuclear materials production of tritium and plutonium. The Department is currently developing a NEPA compliance strategy for modernization of the remainder of the nuclear weapons production complex, which will reference the EIS on NPR capacity. 7 refs., 8 tabs

  1. Synoptic events force biological productivity in Patagonian fjord ecosystems

    Daneri, Giovanni

    2016-04-01

    The annual cycle of primary productivity of the Patagonian fjords has, to date, been described as a two phase system consisting of a short non productive winter phase (during June and July) and a productive phase extending from late winter (August) to autumn (May). Low levels of primary production, phytoplankton biomass and high concentrations of surface nutrients have been described as characterizing winter conditions while pulsed productivity events typifies the productivity pattern during the extended productive season. Pulsed productivity events characterize coastal waters where inorganic nutrients in surface layers are replenished following periods of intensive utilization by autotrophs. Freshwater input in Patagonian fjords in southern Chile (41-55°S) results in one of the largest estuarine regions worldwide. Here strong haline water column stratification prevents nutrient mixing to the surface layers thus potentially shutting off algal production. Our working hypothesis considered that in order to reconcile the observed pulsed productivity pattern, periodic breaking (associated to surface nutrient replenishment) and re-establishment of estuarine conditions (associated to water column stratification) would be required. Up to now however our understanding of the physical processes that control water column conditions in the Patagonian fjord area has been extremely limited. Here we present evidence linking the passage of synoptic low pressure fronts to pulsed productivity events in the Patagonian fjord area. These front controls and influence local processes of interaction between the fjord and the atmosphere generating a rapid water column response. In the specific case of the Puyuhuapi fjord we have been able to show that such synoptic fronts induce surface flow reversal and water column mixing. Phytoplankton blooming occurs after the passage of the synoptic front once calmer conditions prevail and estuarine conditions are re established. The occurrence of

  2. Force decay of elastomeric chains - a mechanical design and product comparison study.

    Balhoff, David A; Shuldberg, Matthew; Hagan, Joseph L; Ballard, Richard W; Armbruster, Paul C

    2011-03-01

    To evaluate the percentage force decay of elastomeric chain products utilizing three different design mechanisms simulating canine retraction; and to evaluate the percentage force decay of elastomeric chain products from four different companies. In vitro, laboratory study. LSUHSC Dental School, New Orleans, LA, USA. Closed (non-spaced), grey elastomeric chains from four companies were selected for the study. Three acrylic resin jigs were constructed to provide a framework for three simulated space closure mechanisms. The 6-5-3, the chain loop, and the 6-3 were the configuration mechanisms used in the study. An electronic force gauge was used to measure the percentage force decay associated with each elastomeric chain over 28 days at preselected times. There was a significant difference in the mean percentage force decay for the three different mechanisms (P < 0·001). For all four companies, the 6-3 mechanical design had the smallest mean percentage force decay. There was a significant difference in the mean percentage force decay for the different companies (P < 0·001). For all three mechanisms, Ormco had the smallest percentage force decay while Unitek had the highest percentage force decay. The significant difference in the mean percentage force decay for the different mechanisms suggests that the 6-3 design is a more efficient means of closing extraction spaces utilizing elastomeric chains.

  3. Improving the hydrogen production capacity of Rhodobacter capsulatus by genetically modifying redox balancing pathways

    Oeztuerk, Yavuz [TUEBITAK Research Institute for Genetic Engineering and Biotechnology, Gebze Kocaeli (Turkey); Goekce, Abdulmecit [Istanbul Technical Univ. (Turkey). Dept. of Molecular Biology and Genetics; Guergan, Muazzez; Yuecel, Meral [Middle East Technical Univ., Ankara (Turkey). Dept. of Biology

    2010-07-01

    In Rhodobacter capsulatus, balancing the oxidation-reduction potential (redox-balance) is maintained via a number of inter-dependent regulatory mechanisms that enable these organisms to accommodate divergent growth modes. In order to maintain redox homeostasis, this bacterium possesses regulatory mechanisms functioning as electron sinks affecting the oxidation-reduction state of the ubiquinone pool. Under the photoheterotrophic growth conditions with reduced carbon sources, the excess reducing equivalents are primarily consumed via the reduction of CO{sub 2} through the Calvin-Benson-Bassham (CBB) pathway or by the reduction of protons into hydrogen with the use of dinitrogenase enzyme system. In this study, our aim was to develop strategies to funnel the excess reducing equivalents to nitrogenase-dependent hydrogen production by blocking the carbon-fixation pathway. To realize this purpose, CO{sub 2} fixation was blocked by inactivating the Phosphoribulokinase (PRK) of CBB pathway in wild type (MT1131), uptake-hydrogenase (YO3) and cyt cbb{sub 3} oxidase deficient (YO4) strains. The hydrogen production capacity of newly generated strains deficient in the Calvin-Benson-Bassham pathway were analyzed and compared with wild type strains. The results indicated that, the hydrogen production efficiency and capacity of R. capsulatus was further improved by directing the excess reducing equivalents to dinitrogenase-dependent hydrogen production. (orig.)

  4. Radial force distribution changes associated with tangential force production in cylindrical grasping, and the importance of anatomical registration.

    Pataky, Todd C; Slota, Gregory P; Latash, Mark L; Zatsiorsky, Vladimir M

    2012-01-10

    Radial force (F(r)) distributions describe grip force coordination about a cylindrical object. Recent studies have employed only explicit F(r) tasks, and have not normalized for anatomical variance when considering F(r) distributions. The goals of the present study were (i) to explore F(r) during tangential force production tasks, and (ii) to examine the extent to which anatomical registration (i.e. spatial normalization of anatomically analogous structures) could improve signal detectability in F(r) data. Twelve subjects grasped a vertically oriented cylindrical handle (diameter=6 cm) and matched target upward tangential forces of 10, 20, and 30 N. F(r) data were measured using a flexible pressure mat with an angular resolution of 4.8°, and were registered using piecewise-linear interpolation between five manually identified points-of-interest. Results indicate that F(r) was primarily limited to three contact regions: the distal thumb, the distal fingers, and the fingers' metatacarpal heads, and that, while increases in tangential force caused significant increases in F(r) for these regions, they did not significantly affect the F(r) distribution across the hand. Registration was found to substantially reduce between-subject variability, as indicated by both accentuated F(r) trends, and amplification of the test statistic. These results imply that, while subjects focus F(r) primarily on three anatomical regions during cylindrical grasp, inter-subject anatomical differences introduce a variability that, if not corrected for via registration, may compromise one's ability to draw anatomically relevant conclusions from grasping force data. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. Calibrated atomic force microscope measurements of vickers hardness indentations and tip production and characterisation for scanning tunelling microscope

    Jensen, Carsten P.

    Calibrated atomic force microscope measurements of vickers hardness indentations and tip production and characterisation for scanning tunelling microscope......Calibrated atomic force microscope measurements of vickers hardness indentations and tip production and characterisation for scanning tunelling microscope...

  6. Peak capacity, peak-capacity production rate, and boiling point resolution for temperature-programmed GC with very high programming rates

    Grall; Leonard; Sacks

    2000-02-01

    Recent advances in column heating technology have made possible very fast linear temperature programming for high-speed gas chromatography. A fused-silica capillary column is contained in a tubular metal jacket, which is resistively heated by a precision power supply. With very rapid column heating, the rate of peak-capacity production is significantly enhanced, but the total peak capacity and the boiling-point resolution (minimum boiling-point difference required for the separation of two nonpolar compounds on a nonpolar column) are reduced relative to more conventional heating rates used with convection-oven instruments. As temperature-programming rates increase, elution temperatures also increase with the result that retention may become insignificant prior to elution. This results in inefficient utilization of the down-stream end of the column and causes a loss in the rate of peak-capacity production. The rate of peak-capacity production is increased by the use of shorter columns and higher carrier gas velocities. With high programming rates (100-600 degrees C/min), column lengths of 6-12 m and average linear carrier gas velocities in the 100-150 cm/s range are satisfactory. In this study, the rate of peak-capacity production, the total peak capacity, and the boiling point resolution are determined for C10-C28 n-alkanes using 6-18 m long columns, 50-200 cm/s average carrier gas velocities, and 60-600 degrees C/min programming rates. It was found that with a 6-meter-long, 0.25-mm i.d. column programmed at a rate of 600 degrees C/min, a maximum peak-capacity production rate of 6.1 peaks/s was obtained. A total peak capacity of about 75 peaks was produced in a 37-s long separation spanning a boiling-point range from n-C10 (174 degrees C) to n-C28 (432 degrees C).

  7. Confinement forces in fast backward nucleon production off nuclei

    Kopeliovich, B.Z.; Niedermayer, F.

    1982-01-01

    Multiple colour exchange mechanism is proposed to describe fast backward nucleon production off nuclei at high energies. Cross section of hd → psub(B)X reaction is calculated in the colour flux tube model. This contribution is found to dominate in the hard part of momentum spectra

  8. Semantic and syntactic forces in noun phrase production

    Vigliocco, G.; Lauer, M.; Damian, M.F.; Levelt, W.J.M.

    2002-01-01

    Three experiments investigated semantic and syntactic effects in the production of phrases in Dutch. Bilingual participants were presented with English nouns and were asked to produce an adjective + noun phrase in Dutch including the translation of the noun. In 2 experiments, the authors blocked

  9. Antioxidant Capacity Determination in Plants and Plant-Derived Products: A Review

    Pop, Aneta; Cimpeanu, Carmen; Predoi, Gabriel

    2016-01-01

    The present paper aims at reviewing and commenting on the analytical methods applied to antioxidant and antioxidant capacity assessment in plant-derived products. Aspects related to oxidative stress, reactive oxidative species' influence on key biomolecules, and antioxidant benefits and modalities of action are discussed. Also, the oxidant-antioxidant balance is critically discussed. The conventional and nonconventional extraction procedures applied prior to analysis are also presented, as the extraction step is of pivotal importance for isolation and concentration of the compound(s) of interest before analysis. Then, the chromatographic, spectrometric, and electrochemical methods for antioxidant and antioxidant capacity determination in plant-derived products are detailed with respect to their principles, characteristics, and specific applications. Peculiarities related to the matrix characteristics and other factors influencing the method's performances are discussed. Health benefits of plants and derived products are described, as indicated in the original source. Finally, critical and conclusive aspects are given when it comes to the choice of a particular extraction procedure and detection method, which should consider the nature of the sample, prevalent antioxidant/antioxidant class, and the mechanism underlying each technique. Advantages and disadvantages are discussed for each method. PMID:28044094

  10. Procyanidin and catechin contents and antioxidant capacity of cocoa and chocolate products.

    Gu, Liwei; House, Suzanne E; Wu, Xianli; Ou, Boxin; Prior, Ronald L

    2006-05-31

    Cocoa and chocolate products from major brands were analyzed blind for total antioxidant capacity (AOC) (lipophilic and hydrophilic ORAC(FL)), catechins, and procyanidins (monomer through polymers). Accuracy of analyses was ascertained by comparing analyses on a NIST standard reference chocolate with NIST certified values. Procyanidin (PC) content was related to the nonfat cocoa solid (NFCS) content. The natural cocoa powders (average 87% of NFCS) contained the highest levels of AOC (826 +/- 103 micromol of TE/g) and PCs (40.8 +/- 8.3 mg/g). Alkalized cocoa (Dutched powders, average 80% NFCS) contained lower AOC (402 +/- 6 micromol of TE /g) and PCs (8.9 +/- 2.7 mg/g). Unsweetened chocolates or chocolate liquor (50% NFCS) contained 496 +/- 40 micromol of TE /g of AOC and 22.3 +/- 2.9 mg/g of PCs. Milk chocolates, which contain the least amount of NFCS (7.1%), had the lowest concentrations of AOC (80 +/- 10 micromol of TE /g) and PCs (2.7 +/- 0.5 mg/g). One serving of cocoa (5 g) or chocolate (15 or 40 g, depending upon the type of chocolate) provides 2000-9100 micromol of TE of AOC and 45-517 mg of PCs, amounts that exceed the amount in a serving of the majority of foods consumed in America. The monomers through trimers, which are thought to be directly bioavailable, contributed 30% of the total PCs in chocolates. Hydrophilic antioxidant capacity contributed >90% of AOC in all products. The correlation coefficient between AOC and PCs in chocolates was 0.92, suggesting that PCs are the dominant antioxidants in cocoa and chocolates. These results indicate that NFCS is correlated with AOC and PC in cocoa and chocolate products. Alkalizing dramatically decreased both the procyanidin content and antioxidant capacity, although not to the same extent.

  11. The multiple roles of titin in muscle contraction and force production.

    Herzog, Walter

    2018-01-20

    Titin is a filamentous protein spanning the half-sarcomere, with spring-like properties in the I-band region. Various structural, signaling, and mechanical functions have been associated with titin, but not all of these are fully elucidated and accepted in the scientific community. Here, I discuss the primary mechanical functions of titin, including its accepted role in passive force production, stabilization of half-sarcomeres and sarcomeres, and its controversial contribution to residual force enhancement, passive force enhancement, energetics, and work production in shortening muscle. Finally, I provide evidence that titin is a molecular spring whose stiffness changes with muscle activation and actin-myosin-based force production, suggesting a novel model of force production that, aside from actin and myosin, includes titin as a "third contractile" filament. Using this three-filament model of sarcomeres, the stability of (half-) sarcomeres, passive force enhancement, residual force enhancement, and the decrease in metabolic energy during and following eccentric contractions can be explained readily.

  12. Forced decontamination of fission products deposited on urban areas

    Warming, L.

    1984-12-01

    Long-lived fission products may be deposited in the environment following a serious reactor accident. Areas of special concern are cities where the collective dose might be high because of the population. An extensive literature list is presented here. Only a few of the references deal with the problem as a whole. Some references deal with non-radiaoctive materials but give us useful information about the behaviour of particles on outdoor surfaces. (author)

  13. Bidirectional transfer between joint and individual actions in a task of discrete force production.

    Masumoto, Junya; Inui, Nobuyuki

    2017-07-01

    The present study examined bidirectional learning transfer between joint and individual actions involving discrete isometric force production with the right index finger. To examine the effects of practice of joint action on performance of the individual action, participants performed a pre-test (individual condition), practice blocks (joint condition), and a post-test (individual condition) (IJI task). To examine the effects of practice of the individual action on performance during the joint action, the participants performed a pre-test (joint condition), practice blocks (individual condition), and a post-test (joint condition) (JIJ task). Whereas one participant made pressing movements with a target peak force of 10% maximum voluntary contraction (MVC) in the individual condition, two participants produced the target force of the sum of 10% MVC produced by each of them in the joint condition. In both the IJI and JIJ tasks, absolute errors and standard deviations of peak force were smaller post-test than pre-test, indicating bidirectional transfer between individual and joint conditions for force accuracy and variability. Although the negative correlation between forces produced by two participants (complementary force production) became stronger with practice blocks in the IJI task, there was no difference between the pre- and post-tests for the negative correlation in the JIJ task. In the JIJ task, the decrease in force accuracy and variability during the individual action did not facilitate complementary force production during the joint action. This indicates that practice performed by two people is essential for complementary force production in joint action.

  14. EFL Speech Production: Exploring the relationship between working memory capacity and proficiency level

    Gicele Vergine Vieira PREBIANCA

    2013-12-01

    Full Text Available The present study explores the relationship between working memory capacity (WMC and proficiency level in EFL1 speech production. Forty-one participants performed two WMC tests – the Speaking Span Test in L1 and in L2. The statistical analysis indicated both a variation on WMC scores in L2 as a function of proficiency as well as a difference between WMC scores in L1 and in L2. Findings are explained mainly in respect to the interplay between automatic and controlled processes on memory retrieval and on the development of L2 proficiency.

  15. A Production Planning Model for Make-to-Order Foundry Flow Shop with Capacity Constraint

    Xixing Li

    2017-01-01

    Full Text Available The mode of production in the modern manufacturing enterprise mainly prefers to MTO (Make-to-Order; how to reasonably arrange the production plan has become a very common and urgent problem for enterprises’ managers to improve inner production reformation in the competitive market environment. In this paper, a mathematical model of production planning is proposed to maximize the profit with capacity constraint. Four kinds of cost factors (material cost, process cost, delay cost, and facility occupy cost are considered in the proposed model. Different factors not only result in different profit but also result in different satisfaction degrees of customers. Particularly, the delay cost and facility occupy cost cannot reach the minimum at the same time; the two objectives are interactional. This paper presents a mathematical model based on the actual production process of a foundry flow shop. An improved genetic algorithm (IGA is proposed to solve the biobjective problem of the model. Also, the gene encoding and decoding, the definition of fitness function, and genetic operators have been illustrated. In addition, the proposed algorithm is used to solve the production planning problem of a foundry flow shop in a casting enterprise. And comparisons with other recently published algorithms show the efficiency and effectiveness of the proposed algorithm.

  16. Exploring crude oil production and export capacity of the OPEC Middle East countries

    Matsumoto, Ken'ichi; Voudouris, Vlasios; Stasinopoulos, Dimitrios; Rigby, Robert; Di Maio, Carlo

    2012-01-01

    As the world economy highly depends on crude oil, it is important to understand the dynamics of crude oil production and export capacity of major oil-exporting countries. Since crude oil resources are predominately located in the OPEC Middle East, these countries are expected to have significant leverage in the world crude oil markets by taking into account a range of uncertainties. In this study, we develop a scenario for crude oil export and production using the ACEGES model considering uncertainties in the resource limits, demand growth, production growth, and peak/decline point. The results indicate that the country-specific peak of both crude oil export and production comes in the early this century in the OPEC Middle East countries. On the other hand, they occupy most of the world export and production before and after the peak points. Consequently, these countries are expected to be the key group in the world crude oil markets. We also find that the gap between the world crude oil demand and production broadens over time, meaning that the acceleration of the development of ultra-deep-water oil, oil sands, and extra-heavy oil will be required if the world continuous to heavily rely on oil products. - Highlights: ► We simulate the future scenario of crude oil export and production using ACEGES. ► The simulated results are analyzed using the GAMLSS framework. ► The peak points of oil export and production will come early in this century. ► The OPCE Middle East will produce most of the world crude oil in the near future. ► These countries will continuously be the key players in the crude oil markets.

  17. Global exploration and production capacity for platinum-group metals from 1995 through 2015

    Wilburn, David R.

    2012-01-01

    Platinum-group metals (PGMs) are required in a variety of commercial, industrial, and military applications for many existing and emerging technologies, yet the United States is highly dependent on foreign sources of PGMs. Information on global exploration for PGMs since 1995 has been used in this study as a basis for identifying locations where the industry has determined that exploration has provided data sufficient to warrant development of a new mine or expansion of an existing operation or where a significant increase in capacity for PGMs is anticipated by 2015. Discussions include an overview of the industry and the selected sites, factors affecting mineral supply, and circumstances leading to the development of mineral properties with the potential to affect mineral supply. Of the 52 sites or regional operations that were considered in this analysis, 16 sites were producing before 1995, 28 sites commenced production from 1995 through 2010, and 8 sites were expected to begin production from 2011 through 2015 if development plans came to fruition. The United States imports PGMs primarily from Canada, Russia, South Africa, and Zimbabwe to meet increasing demand for these materials in a variety of specialized and high-tech applications. Feed sources of PGMs are changing in South Africa and Russia, which together accounted for about 89 percent of platinum production and 82 percent of palladium production in 2009. A greater amount of South African PGM capacity is likely to come from deeper, higher cost Upper Group Reef seam 2 deposits and deposits in the Eastern Bushveld area. Future Russian PGM capacity is likely to come from ore zones with generally lower PGM content and different platinum-to-palladium ratios than the nickel-rich ore that dominated PGM supply in the 1990s. Because PGM supply from Canada and Russia is derived as a byproduct of copper and nickel mining, the PGM supply from these countries is influenced by economic, environmental, political, and

  18. Force Field Benchmark of Organic Liquids: Density, Enthalpy of Vaporization, Heat Capacities, Surface Tension, Isothermal Compressibility, Volumetric Expansion Coefficient, and Dielectric Constant.

    Caleman, Carl; van Maaren, Paul J; Hong, Minyan; Hub, Jochen S; Costa, Luciano T; van der Spoel, David

    2012-01-10

    The chemical composition of small organic molecules is often very similar to amino acid side chains or the bases in nucleic acids, and hence there is no a priori reason why a molecular mechanics force field could not describe both organic liquids and biomolecules with a single parameter set. Here, we devise a benchmark for force fields in order to test the ability of existing force fields to reproduce some key properties of organic liquids, namely, the density, enthalpy of vaporization, the surface tension, the heat capacity at constant volume and pressure, the isothermal compressibility, the volumetric expansion coefficient, and the static dielectric constant. Well over 1200 experimental measurements were used for comparison to the simulations of 146 organic liquids. Novel polynomial interpolations of the dielectric constant (32 molecules), heat capacity at constant pressure (three molecules), and the isothermal compressibility (53 molecules) as a function of the temperature have been made, based on experimental data, in order to be able to compare simulation results to them. To compute the heat capacities, we applied the two phase thermodynamics method (Lin et al. J. Chem. Phys.2003, 119, 11792), which allows one to compute thermodynamic properties on the basis of the density of states as derived from the velocity autocorrelation function. The method is implemented in a new utility within the GROMACS molecular simulation package, named g_dos, and a detailed exposé of the underlying equations is presented. The purpose of this work is to establish the state of the art of two popular force fields, OPLS/AA (all-atom optimized potential for liquid simulation) and GAFF (generalized Amber force field), to find common bottlenecks, i.e., particularly difficult molecules, and to serve as a reference point for future force field development. To make for a fair playing field, all molecules were evaluated with the same parameter settings, such as thermostats and barostats

  19. Production capacity of biomass of the floodpain community of Salix alba L. in southern Moravia

    Diana López

    2007-01-01

    Full Text Available The paper deals with the study of the production capacity of biomass in the seven-year stand of Salix alba L. The communities originated in the process of primary succession in the area of the middle Nové Mlýny reservoir on a newly established island. Already since the first stages, the communities have been monitored. Results have shown that white willow behaves as an R-strategist with fast growth in youth. Moreover, the growth is supported by optimum environmental conditions (soils richly supplied with nutrients and water, long growing season. Accumulated phytomass amounted 102,7 t.ha−1 at the age of 7 years and the yield reached a mean annual increment of 15 t.ha−1.year−1. Communities of white willow rank among highly productive phytocoenoses capable of fixing considerable amounts of carbon and, at the same time fulfilling the function of habitat corridors.

  20. Scaling up the production capacity of U-Mo powder by HMD process

    Pasqualini, E.E.; Lopez, M.; Helzel Garcia, L.J.; Echenique, P.; Adelfang, P.

    2002-01-01

    The recent discovery that uranium alloys in metastable gamma phase can be hydrided at low temperatures and pressures have allowed developing the method of commuting bulk materials by milling the hydride to desired size and then dehydriding the powder. This process is called HMD (hydriding-milling-dehydriding) and needs an initial step of hydrogen incorporation to allow the alloy to be hydrided. This four step process has been conveniently set up for the production of U-7Mo powder for its use in nuclear fuels. Low equipment investment and low man power are needed for this achievement. The process is being analyzed in its scaling up for one kilogram batches and a 50 kilogram per year production capacity of U-Mo powder. (author)

  1. The Use of Absorptive Capacity in Improving the New Product Development (NPD

    Gunawan, W.; Gerardus, P.; Tji, B. J.; Richard, K.

    2017-01-01

    The term Absorptive Capacity (AC) refers to maximizing the external knowledge transfer into the organization in order to improve its performance. Since its introduction in year 1990, AC has been applied widely in many fields such as: economy, business, KM, HR, intellectual capital, IT, operation management, marketing, etc. Due to its wide application, nevertheless, The AC application in both Indonesian industry and higher education institutions (HEIs) are still rare to find. The Indonesian Directorate General of Higher Education (DGHE) has encouraged creating effective collaboration model that enables to link the HEIs with the industries in order to improve knowledge creation in improving product development that can be used by the firms. For this reason, the article examines the effective AC model that enables to assist in improving new product development (NPD) process in the polytechnic perspectives.

  2. Effects of spray drying on antioxidant capacity and anthocyanidin content of blueberry by-products.

    Lim, Kar; Ma, Mitzi; Dolan, Kirk D

    2011-09-01

    The effect of spray drying on degradation of nutraceutical components in cull blueberry extract was investigated. Samples collected before and after spray drying were tested for antioxidant capacity using oxygen radical absorbance capacity (ORAC(FL) ) and total phenolics; and for individual anthocyanidins. In Study 1, four different levels of maltodextrin (blueberry solids to maltodextrin ratios of 5: 95, 10: 90, 30: 70, and 50: 50) were spray dried a pilot-scale spray dryer. There was significantly higher retention of nutraceutical components with increased levels of maltodextrin indicating a protective effect of maltodextrin on the nutraceutical components during spray drying. In Study 2, the air inlet temperature of the spray dryer was kept constant for all runs at 150 °C, with 2 different outlet temperatures of 80 and 90 °C. The degradation of nutraceutical components was not significantly different at the 2 selected outlet temperatures. ORAC(FL) reduction for blueberry samples after spray drying was 66.3% to 69.6%. After spray drying, total phenolics reduction for blueberry was 8.2% to 17.5%. Individual anthocyanidin reduction for blueberry was 50% to 70%. The experimental spray dried powders compared favorably to commercial blueberry powders. Results of the study show that use of blueberry by-products is feasible to make a value-added powder. Results can be used by producers to estimate final nutraceutical content of spray-dried blueberry by-products. © 2011 Institute of Food Technologists®

  3. Plasma temperature during methylene blue/light treatment influences virus inactivation capacity and product quality.

    Gravemann, U; Handke, W; Sumian, C; Alvarez, I; Reichenberg, S; Müller, T H; Seltsam, A

    2018-02-27

    Photodynamic treatment using methylene blue (MB) and visible light is in routine use for pathogen inactivation of human plasma in different countries. Ambient and product temperature conditions for human plasma during production may vary between production sites. The influence of different temperature conditions on virus inactivation capacity and plasma quality of the THERAFLEX MB-Plasma procedure was investigated in this study. Plasma units equilibrated to 5 ± 2°C, room temperature (22 ± 2°C) or 30 ± 2°C were treated with MB/light and comparatively assessed for the inactivation capacity for three different viruses, concentrations of MB and its photoproducts, activity of various plasma coagulation factors and clotting time. Reduced solubility of the MB pill was observed at 5 ± 2°C. Photocatalytic degradation of MB increased with increasing temperature, and the greatest formation of photoproducts (mainly azure B) occurred at 30 ± 2°C. Inactivation of suid herpesvirus, bovine viral diarrhoea virus and vesicular stomatitis virus was significantly lower at 5 ± 2°C than at higher temperatures. MB/light treatment affected clotting times and the activity of almost all investigated plasma proteins. Factor VIII (-17·7 ± 8·3%, 22 ± 2°C) and fibrinogen (-14·4 ± 16·4%, 22 ± 2°C) showed the highest decreases in activity. Increasing plasma temperatures resulted in greater changes in clotting time and higher losses of plasma coagulation factor activity. Temperature conditions for THERAFLEX MB-Plasma treatment must be carefully controlled to assure uniform quality of pathogen-reduced plasma in routine production. Inactivation of cooled plasma is not recommended. © 2018 International Society of Blood Transfusion.

  4. Decomposition principles applied to the dynamic production and work-force scheduling problem

    Aardal, K.I.; Ari, A.

    1987-01-01

    One of the most important problems in the production and inventory planning field, is the scheduling of production and work force in a dynamic environment. Although this problem can be formulated as a linear program, it is often quite difficult to solve directly, due to its large scale. Instead, it

  5. Explosive force production during isometric squats correlates with athletic performance in rugby union players.

    Tillin, Neale Anthony; Pain, Matthew Thomas Gerard; Folland, Jonathan

    2013-01-01

    This study investigated the association between explosive force production during isometric squats and athletic performance (sprint time and countermovement jump height). Sprint time (5 and 20 m) and jump height were recorded in 18 male elite-standard varsity rugby union players. Participants also completed a series of maximal- and explosive-isometric squats to measure maximal force and explosive force at 50-ms intervals up to 250 ms from force onset. Sprint performance was related to early phase (≤100 ms) explosive force normalised to maximal force (5 m, r = -0.63, P = 0.005; and 20 m, r = -0.54, P = 0.020), but jump height was related to later phase (>100 ms) absolute explosive force (0.51 squats (33-67%; 0.001 squats was associated with athletic performance. Specifically, sprint performance was most strongly related to the proportion of maximal force achieved in the initial phase of explosive-isometric squats, whilst jump height was most strongly related to absolute force in the later phase of the explosive-isometric squats.

  6. Influence of thermal treatment on color, enzyme activities, and antioxidant capacity of innovative pastelike parsley products.

    Kaiser, Andrea; Brinkmann, Maike; Carle, Reinhold; Kammerer, Dietmar R

    2012-03-28

    Conventional spice powders are often characterized by low sensory quality and high microbial loads. Furthermore, genuine enzymes are only inhibited but not entirely inactivated upon drying, so that they may regain their activity upon rehydration of dried foods. To overcome these problems, initial heating was applied in the present study as the first process step for the production of innovative pastelike parsley products. For this purpose, fresh parsley was blanched (80, 90, and 100 °C for 1-10 min) and subsequently comminuted to form a paste. Alternatively, mincing was carried out prior to heat treatment. Regardless of temperature, the color of the latter product did not show any change after heating for 1 min. With progressing exposure time the green color turned to olive hues due to marked pheophytin formation. Inactivation of genuine peroxidase (POD) and polyphenol oxidase (PPO) was achieved at all temperature-time regimes applied. In contrast, the parsley products obtained after immediate water-blanching were characterized by brighter green colors and enhanced pigment retention. With the exception of the variants water-blanched at 80 °C, POD and PPO were completely inactivated at any of the thermal treatments. Furthermore, in water-blanched samples, antioxidant capacities as determined by the TEAC and FRAP assays were even enhanced compared to unheated parsley, whereas a decrease of phenolic contents could not be prevented. Consequently, the innovative process presented in this study allows the production of novel herb and spice products characterized by improved sensory quality as compared to conventional spice products.

  7. Anterior cruciate ligament tear induces a sustained loss of muscle fiber force production.

    Gumucio, Jonathan P; Sugg, Kristoffer B; Enselman, Elizabeth R Sibilsky; Konja, Alexis C; Eckhardt, Logan R; Bedi, Asheesh; Mendias, Christopher L

    2018-01-18

    Patients with anterior cruciate ligament (ACL) tears have persistent quadriceps strength deficits that are thought to be due to altered neurophysiological function. Our goal was to determine the changes in muscle fiber contractility independent of the ability of motor neurons to activate fibers. We obtained quadriceps biopsies of patients undergoing ACL reconstruction, and additional biopsies 1, 2, and 6 months after surgery. Muscles fiber contractility was assessed in vitro, along with whole muscle strength testing. Compared with controls, patients had a 30% reduction in normalized muscle fiber force at the time of surgery. One month later, the force deficit was 41%, and at 6 months the deficit was 23%. Whole muscle strength testing demonstrated similar trends. While neurophysiological dysfunction contributes to whole muscle weakness, there is also a reduction in the force generating capacity of individual muscle cells independent of alpha motor neuron activation. Muscle Nerve, 2018. © 2018 Wiley Periodicals, Inc.

  8. Enhancing the Feed Capacity of Horticulture Agro-Ecosystem Through Technology for Goat Production

    Simon P Ginting

    2011-09-01

    Full Text Available The availability of feed and their efficiency of use throughout the year represent the most important constraint affecting the productivity of animals in any agro-ecosystems. Beside being the largest contributor to the total production cost, logistically feeds need to be available on a daily basis across the animal’s life time. In order to be competitive, goat production system must be directed toward the optimum utilization of inconventional feedstuffs such as crop residues and agro-industrial by-products. The horticulture crops provide various crop-residues and by products from the processing of its main products. These biomass are potential feedstuffs that could be used to support the production of goats. The processing of passion fruits (Passiflora edulis yield by products such as fruit shells and seeds. These products are good energy and protein sources for growing goats. Oriental radish (Raphanus sativus by-products composed by damaged root parts and culls have high digestible energy and low ether extract content, but have very high moisture content. The pineapple by-products composed by the peel and bagasse of the fruit could be used as energy source for goats. Other horticulture by-products or residues such as citrus pulp, abandoned citrus fruit, forages from Ipomea batatas are of great potential as feeds for goat production. Preserving technology like ensiling could be implemented in utilising those biomass categorized as wet by-products such as pineapple and oriental radish by-products. The technology of complete feed is an effective means in utilizing some of those products with relatively low palatability or to increase its inclusion level in diets. Introducing shade-tolerant forage species as intercrops such as Stenotaphrum secundatum, Brachiaria humidicola and Arachis pintoi in the citrus plantation should increase feed capacity of the area. The multi-purpose trees such as Indigofera sp. and Calliandra calothyrsus both are

  9. Opportunistic Market-Driven Regional Shifts of Cropping Practices Reduce Food Production Capacity of China

    Yuan, Wenping; Liu, Shuguang; Liu, Wei; Zhao, Shuqing; Dong, Wenjie; Tao, Fulu; Chen, Min; Lin, Hui

    2018-04-01

    China is facing the challenge of feeding a growing population with the declining cropland and increasing shortage of water resources under the changing climate. This study identified that the opportunistic profit-driven shifts of planting areas and crop species composition have strongly reduced the food production capacity of China. First, the regional cultivation patterns of major crops in China have substantially shifted during the past five decades. Southeast and South China, the regions with abundant water resources and fewer natural disasters, have lost large planting areas of cropland in order to pursue industry and commerce. Meanwhile, Northeast and Northwest China, the regions with low water resources and frequent natural disasters, have witnessed increases in planting areas. These macroshifts have reduced the national food production by 1.02% per year. The lost grain production would have been enough to feed 13 million people. Second, the spatial shifts have been accompanied by major changes in crop species composition, with substantial increases in planting area and production of maize, due to its low water consumption and high economic returns. Consequently, the stockpile of maize in China has accounted for more than half of global stockpile, and the stock to use ratio of maize in China has exceeded the reliable level. Market-driven regional shifts of cropping practices have resulted in larger irrigation requirements and aggravated environmental stresses. Our results highlighted the need for Chinese food policies to consider the spatial shifts in cultivation, and the planting crop compositions limited by regional water resources and climate change.

  10. Capacity of Physiotherapy Workforce Production in Thailand: Public-Private Mix, Secular Trend and Geographic Distribution.

    Kaewsawang, Sarinee; Chongsuvivatwong, Virasakdi; Vongsirinavarat, Mantana

    2016-06-01

    In Thailand, the shortage of physiotherapists has been an increasing concern because of increased health burden from demographic and epidemiologic changes. This study aims to analyse the current situation of the physiotherapy workforce production system, secular trend, geographical distribution and comparison of public and private physiotherapy training institutes. Longitudinal data related to production capacity of the physiotherapy institutes were applied. Data from 2008 to 2012 were obtained from all 16 physiotherapy institutes in Thailand. Data during 2000-2007 were also retrieved from annual reports from the Ministry of Education. Descriptive statistics were initially used. Comparison was made between public and private physiotherapy institutes in terms of the number of students admitted and graduated, number of teachers, annual tuition fee, student-teacher ratio and dropout rate within 1 year. Predictive factors for graduation within 4 years were determined using logistic regression. In Thailand, there was an average of 800 physiotherapy graduates per year. New private institutes have been recently established and have steadily increased student admission rates. However, this has resulted in a high student-teacher ratio (median 7.1, inter-quartile range (IQR) 5.9-10.0). The first-year dropout rate in 2012 was 29.1%. Geographically, the majority of the institutes are clustered in the central region. Multivariate analysis revealed significantly lower probability of graduation within 4 years among students admitted to the private institutes and those in non-north-east region. The production capacity of the physiotherapy workforce is below an estimated need. Private physiotherapy institutes need more support to improve the situation of staff shortages and student graduation rates. The non-central regions should be encouraged to produce more physiotherapists. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  11. Light Quality Dependent Changes in Morphology, Antioxidant Capacity, and Volatile Production in Sweet Basil (Ocimum basilicum).

    Carvalho, Sofia D; Schwieterman, Michael L; Abrahan, Carolina E; Colquhoun, Thomas A; Folta, Kevin M

    2016-01-01

    Narrow-bandwidth light treatments may be used to manipulate plant growth, development and metabolism. In this report LED-based light treatments were used to affect yield and metabolic content of sweet basil (Ocimum basilicum L. cv "Ceasar") grown in controlled environments. This culinary herb produces an aroma highly appreciated by consumers, primarily composed of terpenes/terpenoids, phenylpropanoids, and fatty-acid- derived volatile molecules. Basil plants were grown under narrow-bandwidth light conditions, and leaf area, height, mass, antioxidant capacity and volatile emissions were measured at various time points. The results indicate reproducible significant differences in specific volatiles, and in biochemical classes of volatiles, compared to greenhouse grown plants. For example, basil plants grown under blue/red/yellow or blue/red/green wavelengths emit higher levels of a subset of monoterpenoid volatiles, while a blue/red/far-red treatment leads to higher levels of most sesquiterpenoid volatile molecules. Specific light treatments increase volatile content, mass, and antioxidant capacity. The results show that narrow-bandwidth illumination can induce discrete suites of volatile classes that affect sensory quality in commercial herbs, and may be a useful tool in improving commercial production.

  12. A vectorial capacity product to monitor changing malaria transmission potential in epidemic regions of Africa

    Ceccato, Pietro; Vancutsem, Christelle; Klaver, Robert; Rowland, James; Connor, Stephen J.

    2012-01-01

    Rainfall and temperature are two of the major factors triggering malaria epidemics in warm semi-arid (desert-fringe) and high altitude (highland-fringe) epidemic risk areas. The ability of the mosquitoes to transmit Plasmodium spp. is dependent upon a series of biological features generally referred to as vectorial capacity. In this study, the vectorial capacity model (VCAP) was expanded to include the influence of rainfall and temperature variables on malaria transmission potential. Data from two remote sensing products were used to monitor rainfall and temperature and were integrated into the VCAP model. The expanded model was tested in Eritrea and Madagascar to check the viability of the approach. The analysis of VCAP in relation to rainfall, temperature and malaria incidence data in these regions shows that the expanded VCAP correctly tracks the risk of malaria both in regions where rainfall is the limiting factor and in regions where temperature is the limiting factor. The VCAP maps are currently offered as an experimental resource for testing within Malaria Early Warning applications in epidemic prone regions of sub-Saharan Africa. User feedback is currently being collected in preparation for further evaluation and refinement of the VCAP model.

  13. Biofilm-forming capacity in biogenic amine-producing bacteria isolated from dairy products.

    Maria eDiaz

    2016-05-01

    Full Text Available Biofilms on the surface of food industry equipment are reservoirs of potentially food-contaminating bacteria - both spoilage and pathogenic. However, the capacity of biogenic amine (BA-producers to form biofilms has remained largely unexamined. BAs are low molecular weight, biologically active compounds that in food can reach concentrations high enough to be a toxicological hazard. Fermented foods, especially some types of cheese, accumulate the highest BA concentrations of all. The present work examines the biofilm-forming capacity of 56 BA-producing strains belonging to three genera and 10 species (12 Enterococcus faecalis, 6 Enterococcus faecium, 6 Enterococcus durans, 1 Enterococcus hirae, 12 Lactococcus lactis, 7 Lactobacillus vaginalis, 2 Lactobacillus curvatus, 2 Lactobacillus brevis, 1 Lactobacillus reuteri and 7 Lactobacillus parabuchneri, all isolated from dairy products. Strains of all the tested species - except for L. vaginalis - were able to produce biofilms on polystyrene and adhered to stainless steel. However, the biomass produced in biofilms was strain-dependent. These results suggest that biofilms may provide a route via which fermented foods can become contaminated by BA-producing microorganisms.

  14. The Global Experience of Development of the Theory of Spatial Distribution of Productive Forces

    Heiman Oleh A.

    2016-01-01

    Full Text Available The publication is aimed at theoretical generalization of the global experience of development of the theory of spatial distribution of productive forces as the basis of regional economy. Considering the evolution of scientific views on the spatial development of territories, taking account of the particularities of the distribution of production, one can allocate and identify several paradigms, which replaced each other, but preserved their connection with the placement of productive forces. Each one of these paradigms or all of them as a whole provide an example of a single historical process associated with the productive forces. Characteristic of a methodology based on the spatiotemporal paradigm is consideration of both time and space factors, which, in substance, take on the qualities of economic categories. Speaking of the use of theoretical developments in the practice of regional development, it should be specified that programs, strategies and other regulations must take into account the linkage between the progressive and the negative trends as well as cyclical nature of economic development, including the global economy, identify the factors that accelerate or retard the passage of every evolutionary spiral, and observe consistency of the productive forces of region with the technological patterns of production.

  15. Wind farm production cost: Optimum turbine size and farm capacity in the actual market

    Laali, A.R.; Meyer, J.L.; Bellot, C. [Electricite de France, Chatou (France); Louche, A. [Espace de Recherche, Ajaccio (France)

    1996-12-31

    Several studies are undertaken in R&D Division of EDF in collaboration with ERASME association in order to have a good knowledge of the wind energy production costs. These studies are performed in the framework of a wind energy monitoring project and concern the influence of a few parameters like wind farm capacity, turbine size and wind speed on production costs, through an analysis of the actual market trend. Some 50 manufacturers and 140 different kind of wind turbines are considered for this study. The minimum production cost is situated at 800/900 kW wind turbine rated power. This point will probably move to more important powers in the future. This study is valid only for average conditions and some special parameters like particular climate conditions or lack of infrastructure for a special site the could modify the results shown on the curves. The variety of wind turbines (rated power as a function of rotor diameter, height and specific rated power) in the actual market is analyzed. A brief analysis of the market trend is also performed. 7 refs., 7 figs.

  16. Adaptive estimation of the electromotive force of the lithium-ion battery after current interruption for an accurate state-of-charge and capacity determination

    Waag, Wladislaw; Sauer, Dirk Uwe

    2013-01-01

    Highlights: • New adaptive approach for the EMF estimation. • The EMF is estimated by observing the voltage change after the current interruption. • The approach enables an accurate SoC and capacity determination. • Real-time capable algorithm. - Abstract: The online estimation of battery states and parameters is one of the challenging tasks when battery is used as a part of the pure electric or hybrid energy system. For the determination of the available energy stored in the battery, the knowledge of the present state-of-charge (SOC) and capacity of the battery is required. For SOC and capacity determination often the estimation of the battery electromotive force (EMF) is employed. The electromotive force can be measured as an open circuit voltage (OCV) of the battery when a significant time has elapsed since the current interruption. This time may take up to some hours for lithium-ion batteries and is needed to eliminate the influence of the diffusion overvoltages. This paper proposes a new approach to estimate the EMF by considering the OCV relaxation process within only some first minutes after the current interruption. The approach is based on an online fitting of an OCV relaxation model to the measured OCV relaxation curve. This model is based on an equivalent circuit consisting of a voltage source (represents the EMF) in series with the parallel connection of the resistance and a constant phase element (CPE). Based on this fitting the model parameters are determined and the EMF is estimated. The application of this method is exemplarily demonstrated for the state-of-charge and capacity estimation of the lithium-ion battery in an electrical vehicle. In the presented example the battery capacity is determined with the maximal inaccuracy of 2% using the EMF estimated at two different levels of state-of-charge. The real-time capability of the proposed algorithm is proven by its implementation on a low-cost 16-bit microcontroller (Infineon XC2287)

  17. United States Army Special Operations Forces and Building Enduring Partner Enabler Capacity in Operation Enduring Freedom-Philippines

    2014-05-22

    Monograph Director Christopher Marsh, Ph.D. , Seminar Leader Christopher T. Drew, COL, EN , Director, School of Advanced Military...56Robert Nolan , “Terror in the Philippines,” Foreign Policy Association Newsletter, 6 March 2003; Charles H. Briscoe...2007. Moroney, Jennifer, Beth Grill, Joe Hogler, Lianne Kennedy-Boudali, and Christopher Paul. How Successful Are US Efforts to Build Capacity in

  18. Biomechanical force induces the growth factor production in human periodontal ligament-derived cells.

    Ichioka, Hiroaki; Yamamoto, Toshiro; Yamamoto, Kenta; Honjo, Ken-Ichi; Adachi, Tetsuya; Oseko, Fumishige; Mazda, Osam; Kanamura, Narisato; Kita, Masakazu

    2016-01-01

    Although many reports have been published on the functional roles of periodontal ligament (PDL) cells, the mechanisms involved in the maintenance and homeostasis of PDL have not been determined. We investigated the effects of biomechanical force on growth factor production, phosphorylation of MAPKs, and intracellular transduction pathways for growth factor production in human periodontal ligament (hPDL) cells using MAPK inhibitors. hPDL cells were exposed to mechanical force (6 MPa) using a hydrostatic pressure apparatus. The levels of growth factor mRNA and protein were examined by real-time RT-PCR and ELISA. The phosphorylation of MAPKs was measured using BD™ CBA Flex Set. In addition, MAPKs inhibitors were used to identify specific signal transduction pathways. Application of biomechanical force (equivalent to occlusal force) increased the synthesis of VEGF-A, FGF-2, and NGF. The application of biomechanical force increased the expression levels of phosphorylated ERK and p38, but not of JNK. Furthermore, the levels of VEGF-A and NGF expression were suppressed by ERK or p38 inhibitor. The growth factors induced by biomechanical force may play a role in the mechanisms of homeostasis of PDL.

  19. Analysis of supply chain, scale factor, and optimum plant capacity for the production of ethanol from corn stover

    Leboreiro, Jose; Hilaly, Ahmad K.

    2013-01-01

    A detailed model is used to perform a thorough analysis on ethanol production from corn stover via the dilute acid process. The biomass supply chain cost model accounts for all steps needed to source corn stover including collection, transportation, and storage. The manufacturing cost model is based on work done at NREL; attainable conversions of key process parameters are used to calculate production cost. The choice of capital investment scaling function and scaling parameter has a significant impact on the optimum plant capacity. For the widely used exponential function, the scaling factors are functions of plant capacity. The pre-exponential factor decreases with increasing plant capacity while the exponential factor increases as the plant capacity increases. The use of scaling parameters calculated for small plant capacities leads to falsely large optimum plants; data from a wide range of plant capacities is required to produce accurate results. A mathematical expression to scale capital investment for fermentation-based biorefineries is proposed which accounts for the linear scaling behavior of bio-reactors (such as saccharification vessels and fermentors) as well as the exponential nature of all other plant equipment. Ignoring the linear scaling behavior of bio-reactors leads to artificially large optimum plant capacities. The minimum production cost is found to be in the range of 789–830 $ m −3 which is significantly higher than previously reported. Optimum plant capacities are in the range of 5750–9850 Mg d −1 . The optimum plant capacity and production cost are highly sensitive to farmer participation in biomass harvest for low participation rates. -- Highlights: •A detailed model is used to perform a technoeconomic analysis for the production of ethanol from corn stover. •The capital investment scaling factors were found to be a function of plant capacity. •Bio-reactors (such as saccharification vessels and fermentors) in large size

  20. Estimating product-to-product variations in metal forming using force measurements

    Havinga, Gosse Tjipke; Van Den Boogaard, Ton

    2017-01-01

    The limits of production accuracy of metal forming processes can be stretched by the development of control systems for compensation of product-to-product variations. Such systems require the use of measurements from each semi-finished product. These measurements must be used to estimate the final

  1. Effect of External Loading on Force and Power Production During Plyometric Push-ups.

    Hinshaw, Taylour J; Stephenson, Mitchell L; Sha, Zhanxin; Dai, Boyi

    2018-04-01

    Hinshaw, TJ, Stephenson, ML, Sha, Z, and Dai, B. Effect of external loading on force and power production during plyometric push-ups. J Strength Cond Res 32(4): 1099-1108, 2018-One common exercise to train upper-body strength and power is the push-up. Training at the loads that would produce the greatest power is an effective way to increase peak power. The purpose of the current study was to quantify the changes in peak force, peak power, and peak velocity among a modified plyometric push-up and plyometric push-ups with or without external loading in physically active young adults. Eighteen male and 17 female participants completed 4 push-ups: (a) modified plyometric push-up on the knees, (b) plyometric push-up without external loading, (c) plyometric push-up with an external load of 5% of body weight, and (d) plyometric push-up with an external load of 10% of body weight. Two force platforms were set up to collect vertical ground reaction forces at the hands and feet. The modified plyometric push-up demonstrated the lowest force, power, and velocity (5.4≥ Cohen's dz ≥1.2). Peak force and force at peak velocity increased (3.8≥ Cohen's dz ≥0.3) and peak velocity and velocity at peak power decreased (1.4≥ Cohen's dz ≥0.8) for the push-up without external loading compared with the 2 push-ups with external loading. No significant differences were observed for peak power among the push-ups with or without external loading (0.4≥ Cohen's dz ≥0.1). Although peak power is similar with or without external loading, push-ups without external loading may be more beneficial for a quick movement, and push-ups with external loading may be more beneficial for a greater force production.

  2. Alluvial diamond resource potential and production capacity assessment of the Central African Republic

    Chirico, Peter G.; Barthelemy, Francis; Ngbokoto, Francois A.

    2010-01-01

    In May of 2000, a meeting was convened in Kimberley, South Africa, and attended by representatives of the diamond industry and leaders of African governments to develop a certification process intended to assure that rough, exported diamonds were free of conflict concerns. This meeting was supported later in 2000 by the United Nations in a resolution adopted by the General Assembly. By 2002, the Kimberly Process Certification Scheme (KPCS) was ratified and signed by diamond-producing and diamond-importing countries. Over 70 countries were included as members of the KPCS at the end of 2007. To prevent trade in "conflict diamonds" while protecting legitimate trade, the KPCS requires that each country set up an internal system of controls to prevent conflict diamonds from entering any imported or exported shipments of rough diamonds. Every diamond or diamond shipment must be accompanied by a Kimberley Process (KP) certificate and be contained in tamper-proof packaging. The objective of this study was (1) to assess the naturally occurring endowment of diamonds in the Central African Republic (potential resources) based on geological evidence, previous studies, and recent field data and (2) to assess the diamond-production capacity and measure the intensity of mining activity. Several possible methods can be used to estimate the potential diamond resource. However, because there is generally a lack of sufficient and consistent data recording all diamond mining in the Central African Republic and because time to conduct fieldwork and accessibility to the diamond mining areas are limited, two different methodologies were used: the volume and grade approach and the content per kilometer approach. Estimates are that approximately 39,000,000 carats of alluvial diamonds remain in the eastern and western zones of the CAR combined. This amount is roughly twice the total amount of diamonds reportedly exported from the Central African Republic since 1931. Production capacity is

  3. Production bias: A proposed modification of the driving force for void swelling under cascade damage conditions

    Woo, C.H.; Garner, F.A.

    1991-11-01

    A new concept of point-defect production as the main driving force for void swelling under cascade damage conditions is proposed. This concept takes into account the recombination and formation of immobile clusters and loops of vacancies and interstitials in the cascade region. The life times of the clusters and loops due to desolution are strong functions of the temperature, as well as their vacancy and interstitial nature. The resulting biased production of free point defects from the internal sources is shown to be a strong driving force for void swelling. The characteristics of void swelling due to production bias are described and compared with experimental results. We conclude that the production bias concept provides a good description of void swelling under cascade damage conditions

  4. Production bias: A proposed modification of the driving force for void swelling under cascade damage conditions

    Woo, C.H.; Singh, B.N.; Garner, F.A.

    1992-01-01

    A new concept of point defect production as the main driving force for void swelling under cascade damage conditions is proposed. This concept takes into account the recombination and formation of immobile clusters and loops of vacancies and interstitials in the cascade region. The lifetimes of the clusters and loops due to desolution are strong functions of the temperature, as well as their vacancy and interstitial nature. The resulting biased production of free point defects from the internal sources is shown to be a strong driving force for void swelling. The characteristics of void swelling due to production bias are described and compared with experimental results. We conclude that the production bias concept provides a good description of void swelling under cascade damage conditions. (orig.)

  5. Integral capacity and inventory decision making in a simple production system

    Dellaert, N.P.; Flapper, S.D.P.; Tan, T.

    2007-01-01

    Abstract. This paper deals with the integral acquisition of capacity and material in a situation with uncertain demand, with non zero lead-times for the supply of both materials and capacity. Although there is a lot of literature on the time-phased acquisition of capacity and materials, most of this

  6. An investigation using atomic force microscopy nanoindentation of dental enamel demineralization as a function of undissociated acid concentration and differential buffer capacity

    Barbour, Michele E; Shellis, R Peter

    2007-01-01

    Acidic drinks and foodstuffs can demineralize dental hard tissues, leading to a pathological condition known as dental erosion, which is of increasing clinical concern. The first step in enamel dissolution is a demineralization of the outer few micrometres of tissue, which results in a softening of the structure. The primary determinant of dissolution rate is pH, but the concentration of undissociated acid, which is related to buffer capacity, also appears to be important. In this study, atomic force microscopy nanoindentation was used to measure the first initial demineralization (softening) induced within 1 min by exposure to solutions with a range of undissociated acid concentration and natural pH of 3.3 or with an undissociated acid concentration of 10 mmol l -1 and pH adjusted to 3.3. The results indicate that differential buffering capacity is a better determinant of softening than undissociated acid concentration. Under the conditions of these experiments, a buffer capacity of >3 mmol l -1 pH -1 does not have any further effect on dissolution rate. These results imply that differential buffering capacity should be used for preference over undissociated acid concentration or titratable acidity, which are more commonly employed in the literature

  7. An investigation using atomic force microscopy nanoindentation of dental enamel demineralization as a function of undissociated acid concentration and differential buffer capacity

    Barbour, Michele E.; Shellis, R. Peter

    2007-02-01

    Acidic drinks and foodstuffs can demineralize dental hard tissues, leading to a pathological condition known as dental erosion, which is of increasing clinical concern. The first step in enamel dissolution is a demineralization of the outer few micrometres of tissue, which results in a softening of the structure. The primary determinant of dissolution rate is pH, but the concentration of undissociated acid, which is related to buffer capacity, also appears to be important. In this study, atomic force microscopy nanoindentation was used to measure the first initial demineralization (softening) induced within 1 min by exposure to solutions with a range of undissociated acid concentration and natural pH of 3.3 or with an undissociated acid concentration of 10 mmol l-1 and pH adjusted to 3.3. The results indicate that differential buffering capacity is a better determinant of softening than undissociated acid concentration. Under the conditions of these experiments, a buffer capacity of >3 mmol l-1 pH-1 does not have any further effect on dissolution rate. These results imply that differential buffering capacity should be used for preference over undissociated acid concentration or titratable acidity, which are more commonly employed in the literature.

  8. Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears.

    Mendias, Christopher L; Roche, Stuart M; Harning, Julie A; Davis, Max E; Lynch, Evan B; Sibilsky Enselman, Elizabeth R; Jacobson, Jon A; Claflin, Dennis R; Calve, Sarah; Bedi, Asheesh

    2015-01-01

    A persistent atrophy of muscle fibers and an accumulation of fat, collectively referred to as fatty degeneration, commonly occur in patients with chronic rotator cuff tears. The etiology of fatty degeneration and function of the residual rotator cuff musculature have not been well characterized in humans. We hypothesized that muscles from patients with chronic rotator cuff tears have reduced muscle fiber force production, disordered myofibrils, and an accumulation of fat vacuoles. The contractility of muscle fibers from biopsy specimens of supraspinatus muscles of 13 patients with chronic full-thickness posterosuperior rotator cuff tears was measured and compared with data from healthy vastus lateralis muscle fibers. Correlations between muscle fiber contractility, American Shoulder and Elbow Surgeons (ASES) scores, and tear size were analyzed. Histology and electron microscopy were also performed. Torn supraspinatus muscles had a 30% reduction in maximum isometric force production and a 29% reduction in normalized force compared with controls. Normalized supraspinatus fiber force positively correlated with ASES score and negatively correlated with tear size. Disordered sarcomeres were noted, along with an accumulation of lipid-laden macrophages in the extracellular matrix surrounding supraspinatus muscle fibers. Patients with chronic supraspinatus tears have significant reductions in muscle fiber force production. Force production also correlates with ASES scores and tear size. The structural and functional muscle dysfunction of the residual muscle fibers is independent of the additional area taken up by fibrotic tissue. This work may help establish future therapies to restore muscle function after the repair of chronically torn rotator cuff muscles. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  9. Effects of age and content of augmented feedback on learning an isometric force-production task

    van Dijk, Henk; Mulder, Theo; Hermens, Hermie J.

    2007-01-01

    This study addressed the interaction between age and the informational content of feedback on learning an isometric force-production task. Healthy men and women (30 young adults: 20 to 35 years; 30 older adults: 55 to 70 years) were randomly assigned to a certain type of feedback: knowledge of

  10. Large urban projects and social actors : Forces supporting and opposing the production

    Cuenya, B.E.

    2006-01-01

    This research studies, by means of the analysis of a paradigmatic large urban project in Buenos Aires, the production process of a large urban project furthered by the State and directed to create a new centrality. The analysis is focused on the forces supporting and opposition the project that were

  11. The Major Crimes Task Force-Afghanistan: A Case Study and Examination of Implications for Future FBI Capacity Building Programs

    2014-12-01

    CIA payroll .175 It has been reported that the CIA paid “tens of millions of dollars” directly to President Karzai and that similar but smaller payments...Similarly, in Iraq, U.S. efforts to use biometric evidence collected through the exploitation of recovered IEDs was 220 Bueno De Mesquita and Smith...influence with senior HN officials or the political sway of prominent HN officials on its payroll . Of all the U.S. partners in capacity-building efforts

  12. World Energy Balance Outlook and OPEC Production Capacity: Implications for Global Oil Security

    Azadeh M. Rouhani

    2012-07-01

    Full Text Available The imbalance between energy resource availability, demand, and production capacity, coupled with inherent economic and environmental uncertainties make strategic energy resources planning, management, and decision-making a challenging process. In this paper, a descriptive approach has been taken to synthesize the world’s energy portfolio and the global energy balance outlook in order to provide insights into the role of Organization of Petroleum Exporting Countries (OPEC in maintaining “stability” and “balance” of the world’s energy market. This synthesis illustrates that in the absence of stringent policies, i.e., if historical trends of the global energy production and consumption hold into the future, it is unlikely that non-conventional liquid fuels and renewable energy sources will play a dominant role in meeting global energy demand by 2030. This should be a source of major global concern as the world may be unprepared for an ultimate shift to other energy sources when the imminent peak oil production is reached. OPEC’s potential to impact the supply and price of oil could enable this organization to act as a facilitator or a barrier for energy transition policies, and to play a key role in the global energy security through cooperative or non-cooperative strategies. It is argued that, as the global energy portfolio becomes more balanced in the long run, OPEC may change its typical high oil price strategies to drive the market prices to lower equilibria, making alternative energy sources less competitive. Alternatively, OPEC can contribute to a cooperative portfolio management approach to help mitigate the gradually emerging energy crisis and global warming, facilitating a less turbulent energy transition path while there is time.

  13. The influence of capacity management on the unit cost of production: a case study in a flexible plastic packaging company

    Tálita Floriano Goulart Silva

    2013-08-01

    Full Text Available This article presents the relationship between capacity management and cost management in determining the unit cost. The objective was to show how the use of effective capacity decreases the unit cost of manufacturing. For this, follow these steps: 1 Knowledge and analysis of production process and PPPC; 2 Data Collection; 3 Application of the Method Cost Center; 4Verification of the relationship between the Capacity Management and Cost Management. Through the company’s accounting reports, observations and interviews, the following results was possible: knowledge of the production process and functioning of PPCP, measuring the cost of each step of the production process and the unit cost of each product. Subsequently, we compared the unit cost using the effective capacity and normal capacity. The results showed that the unit costs decrease with the use of effective capacity, while increasing the margin for each product, even with the lower sale price, thus establishing a virtuous circle: effective capacity utilization, reduced unit cost, most competitive prices and increase in the number of requests.

  14. Partners of Choice and Necessity: Special Operations Forces and the National Security Imperatives of Building Partner Capacity

    2015-05-21

    intersection of complexity, social interaction, political violence, and military force. Lastly, I owe a tremendous debt to my wife and family for giving me the...space to pursue these intellectual endeavors while “taking a break” from deployment. In partial payment of that debt , I promise not to mention any...Going Big by Getting Small (Denver, CO: Outskirts Press), 162-163. 12 liberalism.19 From the Greek civil war of the late 1940s to the modern

  15. Environmental Assessment: Recapitalization of the 49th WG Combat Capabilities and Capacities, Holloman Air Force Base, New Mexico

    2011-07-01

    anti-aircraft artillery, or another aircraft. A bundle of chaff consists of approximately 5 to 5.6 million fibers (each thinner than a human hair...is governed by detailed operating procedures to ensure safety. Chaff, which is ejected from an aircraft to reflect radar signals, is small fibers of...calcium carbonate rich soils; and erosional debris surrounding bedrock outcrops of limestone, sandstone, shale, gypsum, and basalt (Air Force 1998

  16. A Realistic View of Long-Term Middle East Production Capacity

    Samsam Bakhtiari, Ali [National Iranian Oil Company (NIOC), Tehran (Iran)

    2003-07-01

    The Middle East is a unique landmass bridging the continents of Europe, Africa and Asia. It now consists of fifteen major countries and one neutral zone. Four of these countries (Afghanistan, Israel, Jordan and Lebanon) are practically devoid of commercial oil resources. And the other eleven jointly control oil reserves estimated by Colin Campbell at 805 bnb (42% of world total) -- made up of 758 bnb discovered and 47 bnb yet-to-find. These eleven countries, which produced on average 20.8 mb/d and 19.3 mb/d in 2001 and 2002 respectively, can be subdivided into three categories: (i) the low producers (4 countries); (ii) the mid-size producers (4 countries); and (iii) the three large producers (Iran, Iraq and Saudi Arabia). In order to investigate the Middle East's long-term production capacity, the forecasts and scenarios developed by the following experts or institutions were reviewed: (a) Dr. Campbell; (b) the major international institutions (IEA, EIA, OPEC); (c) the major oil companies; (d) the major international banks; (e) the specialised press; (f) prominent economists and consultants; (g) the simulations of the 'World Oil Production Capacity' (WOCAP) model. The most significant results were derived from Dr. Campbell's predictions and the WOCAP model. Both of these show Middle Eastern producers going through a long 'bumpy plateau' between 2003 and 2020 with a gradual ramping down during the second decade. WOCAP's simulations for each of the large three producers are presented and analysed. All in all, the Middle Eastern countries, which produce nearly a third of global crude oil, will continue to play a major role on the global oil stage, a role that, with time, can only tend to become more predominant. And although the region's oil represents over 40% of global reserves and roughly two-thirds of proved reserves, there are limits to its output. For those believing that for Middle East oil 'the sky's the limit

  17. 78 FR 72714 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

    2013-12-03

    ... DEPARTMENT OF LABOR Child Labor, Forced Labor, and Forced or Indentured Child Labor in the... Child Labor AGENCY: The Bureau of International Labor Affairs, United States Department of Labor. ACTION..., 2013, regarding child labor and forced labor in foreign countries. Relevant information will be used by...

  18. How wing kinematics affect power requirements and aerodynamic force production in a robotic bat wing

    Bahlman, Joseph W; Swartz, Sharon M; Breuer, Kenneth S

    2014-01-01

    Bats display a wide variety of behaviors that require different amounts of aerodynamic force. To control and modulate aerodynamic force, bats change wing kinematics, which, in turn, may change the power required for wing motion. There are many kinematic mechanisms that bats, and other flapping animals, can use to increase aerodynamic force, e.g. increasing wingbeat frequency or amplitude. However, we do not know if there is a difference in energetic cost between these different kinematic mechanisms. To assess the relationship between mechanical power input and aerodynamic force output across different isolated kinematic parameters, we programmed a robotic bat wing to flap over a range of kinematic parameters and measured aerodynamic force and mechanical power. We systematically varied five kinematic parameters: wingbeat frequency, wingbeat amplitude, stroke plane angle, downstroke ratio, and wing folding. Kinematic values were based on observed values from free flying Cynopterus brachyotis, the species on which the robot was based. We describe how lift, thrust, and power change with increases in each kinematic variable. We compare the power costs associated with generating additional force through the four kinematic mechanisms controlled at the shoulder, and show that all four mechanisms require approximately the same power to generate a given force. This result suggests that no single parameter offers an energetic advantage over the others. Finally, we show that retracting the wing during upstroke reduces power requirements for flapping and increases net lift production, but decreases net thrust production. These results compare well with studies performed on C. brachyotis, offering insight into natural flight kinematics. (paper)

  19. Draft environmental impact statement siting, construction, and operation of New Production Reactor capacity. Volume 4, Appendices D-R

    None

    1991-04-01

    This Environmental Impact Statement (EIS) assesses the potential environmental impacts, both on a broad programmatic level and on a project-specific level, concerning a proposed action to provide new tritium production capacity to meet the nation`s nuclear defense requirements well into the 21st century. A capacity equivalent to that of about a 3,000-megawatt (thermal) heavy-water reactor was assumed as a reference basis for analysis in this EIS; this is the approximate capacity of the existing production reactors at DOE`s Savannah River Site near Aiken, South Carolina. The EIS programmatic alternatives address Departmental decisions to be made on whether to build new production facilities, whether to build one or more complexes, what size production capacity to provide, and when to provide this capacity. Project-specific impacts for siting, constructing, and operating new production reactor capacity are assessed for three alternative sites: the Hanford Site near Richland, Washington; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; and the Savannah River Site. For each site, the impacts of three reactor technologies (and supporting facilities) are assessed: a heavy-water reactor, a light-water reactor, and a modular high-temperature gas-cooled reactor. Impacts of the no-action alternative also are assessed. The EIS evaluates impacts related to air quality; noise levels; surface water, groundwater, and wetlands; land use; recreation; visual environment; biotic resources; historical, archaeological, and cultural resources; socioeconomics; transportation; waste management; and human health and safety. The EIS describes in detail the potential radioactive releases from new production reactors and support facilities and assesses the potential doses to workers and the general public. This volume contains 15 appendices.

  20. On the Optimal Policy for the Single-product Inventory Problem with Set-up Cost and a Restricted Production Capacity

    Foreest, N. D. van; Wijngaard, J.

    2010-01-01

    The single-product, stationary inventory problem with set-up cost is one of the classical problems in stochastic operations research. Theories have been developed to cope with finite production capacity in periodic review systems, and it has been proved that optimal policies for these cases are not

  1. Relationship Between Force Production During Isometric Squats and Knee Flexion Angles During Landing.

    Fisher, Harry; Stephenson, Mitchell L; Graves, Kyle K; Hinshaw, Taylour J; Smith, Derek T; Zhu, Qin; Wilson, Margaret A; Dai, Boyi

    2016-06-01

    Decreased knee flexion angles during landing are associated with increased anterior cruciate ligament loading. The underlying mechanisms associated with decreased self-selected knee flexion angles during landing are still unclear. The purpose of this study was to establish the relationship between the peak force production at various knee flexion angles (35, 55, 70, and 90°) during isometric squats and the actual knee flexion angles that occur during landing in both men and women. A total of 18 men and 18 women recreational/collegiate athletes performed 4 isometric squats at various knee flexion angles while vertical ground reaction forces were recorded. Participants also performed a jump-landing-jump task while lower extremity kinematics were collected. For women, significant correlations were found between the peak force production at 55 and 70° of knee flexion during isometric squats and the knee flexion angle at initial contact of landing. There were also significant correlations between the peak force production at 55, 70, and 90° of knee flexion during isometric squats and the peak knee flexion angle during landing. These correlations tended to be stronger during isometric squats at greater knee flexion compared with smaller knee flexion. No significant correlations were found for men. Posture-specific strength may play an important role in determining self-selected knee flexion angles during landing for women.

  2. Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS

    Joshi, Payal; Bhoir, Suvarna; Bhagwat, A. M.; Vishwanath, K.; Jadhav, R. K.

    2011-01-01

    Degradation products of itopride formed under different forced conditions have been identified using LC-PDA and LC-MS techniques. Itopride was subjected to forced degradation under the conditions of hydrolysis, photolysis, oxidation, dry and wet heat, in accordance with the International Conference on Harmonization. The stress solutions were chromatographed on reversed phase C18 (250×4.6 mm, 5 μm) column with a mobile phase methanol:water (55:45, v/v) at a detection wavelength of 215 nm. Itop...

  3. Aviation System Capacity Program Terminal Area Productivity Project: Ground and Airborne Technologies

    Giulianetti, Demo J.

    2001-01-01

    Ground and airborne technologies were developed in the Terminal Area Productivity (TAP) project for increasing throughput at major airports by safely maintaining good-weather operating capacity during bad weather. Methods were demonstrated for accurately predicting vortices to prevent wake-turbulence encounters and to reduce in-trail separation requirements for aircraft approaching the same runway for landing. Technology was demonstrated that safely enabled independent simultaneous approaches in poor weather conditions to parallel runways spaced less than 3,400 ft apart. Guidance, control, and situation-awareness systems were developed to reduce congestion in airport surface operations resulting from the increased throughput, particularly during night and instrument meteorological conditions (IMC). These systems decreased runway occupancy time by safely and smoothly decelerating the aircraft, increasing taxi speed, and safely steering the aircraft off the runway. Simulations were performed in which optimal trajectories were determined by air traffic control (ATC) and communicated to flight crews by means of Center TRACON Automation System/Flight Management System (CTASFMS) automation to reduce flight delays, increase throughput, and ensure flight safety.

  4. Link Between Capacity for Current Production and Syntrophic Growth in Geobacter species

    Amelia-Elena eRotaru

    2015-07-01

    Full Text Available Electrodes are unnatural electron acceptors, and it is yet unknown how some Geobacter species evolved to use electrodes as terminal electron acceptors. Analysis of different Geobacter species revealed that they varied in their capacity for current production. G. metallireducens and G. hydrogenophilus generated high current densities (ca. 0.05 mA/cm2, comparable to G. sulfurreducens. G. bremensis, G. chapellei, G. humireducens, and G. uranireducens, produced much lower currents (ca. 0.05 mA/cm2 and G. bemidjiensis was previously found to not produce current. There was no correspondence between the effectiveness of current generation and Fe(III oxide reduction rates. Some high-current-density strains (G. metallireducens and G. hydrogenophilus reduced Fe(III-oxides as fast as some low-current-density strains (G. bremensis, G. humireducens, and G. uranireducens whereas other low-current-density strains (G. bemidjiensis and G. chapellei reduced Fe(III oxide as slowly as G. sulfurreducens, a high-current-density strain. However, there was a correspondence between the ability to produce higher currents and the ability to grow syntrophically. G. hydrogenophilius was found to grow in co-culture with Methanosarcina barkeri, which is capable of direct interspecies electron transfer (DIET, but not with Methanospirillium hungatei capable only of H2 or formate transfer. Conductive granular activated carbon (GAC stimulated metabolism of the G. hydrogenophilus - M. barkeri co-culture, consistent with electron exchange via DIET. These findings, coupled with the previous finding that G. metallireducens and G. sulfurreducens are also capable of DIET, suggest that evolution to optimize DIET has fortuitiously conferred the capability for high-density current production to some Geobacter species.

  5. Critical force during tethered swimming for the evaluation of aerobic capacity and prediction of performances in freestyle swimming

    Marcelo Papoti; Ricardo Vitório; Gustavo Gomes Araújo; Luiz Eduardo Barreto Martins; Sérgio Augusto Cunha; Claudio Alexandre Gobatto

    2010-01-01

    The present study investigated the relationship of critical force (Fcrit) with lactate threshold (LLNA) and the intensity corresponding to VO2max (iVO2max) in tethered swimming (TS), and their correlation with maximal performance in 400-m (V400) and 30-min (VT30) freestyle swimming (FS). Seven swimmers were submitted to a TS incremental test for the determination of LLNA and iVO2max. For the determination of Fcrit, the swimmers performed four exercises to exhaustion at intensities (F) corresp...

  6. Optimizing the Capacity and Operation of U.S. Army Ammunition Production Facilities

    Bayram, Vedat

    2002-01-01

    .... The Army must also manage and maintain capacity to replenish ammunition consumed by major theater wars without expanding the industrial base, The combined organic and inorganic industrial base...

  7. Continuous theta-burst stimulation to primary motor cortex reveals asymmetric compensation for sensory attenuation in bimanual repetitive force production.

    Therrien, Amanda S; Lyons, James; Balasubramaniam, Ramesh

    2013-08-01

    Studies of fingertip force production have shown that self-produced forces are perceived as weaker than externally generated forces. This is due to mechanisms of sensory reafference where the comparison between predicted and actual sensory feedback results in attenuated perceptions of self-generated forces. Without an external reference to calibrate attenuated performance judgments, a compensatory overproduction of force is exhibited. It remains unclear whether the force overproduction seen in the absence of visual reference stimuli differs when forces are produced bimanually. We studied performance of two versions of a bimanual sequential force production task compared with each hand performing the task unimanually. When the task goal was shared, force series produced by each hand in bimanual conditions were found to be uncorrelated. When the bimanual task required each hand to reach a target force level, we found asymmetries in the degree of force overproduction between the hands following visual feedback removal. Unilateral continuous theta-burst stimulation of the left primary motor cortex yielded a selective reduction of force overproduction in the hand contralateral to stimulation by disrupting sensory reafference processes. While variability was lower in bimanual trials when the task goal was shared, this influence of hand condition disappeared when the target force level was to be reached by each hand simultaneously. Our findings strengthen the notion that force control in bimanual action is less tightly coupled than other mechanisms of bimanual motor control and show that this effector specificity may be extended to the processing and compensation for mechanisms of sensory reafference.

  8. Increased cross-bridge recruitment contributes to transient increase in force generation beyond maximal capacity in human myocardium.

    Milani-Nejad, Nima; Chung, Jae-Hoon; Canan, Benjamin D; Fedorov, Vadim V; Whitson, Bryan A; Kilic, Ahmet; Mohler, Peter J; Janssen, Paul M L

    2018-01-01

    Cross-bridge attachment allows force generation to occur, and rate of tension redevelopment (k tr ) is a commonly used index of cross-bridge cycling rate. Tension overshoots have been observed briefly after a slack-restretch k tr maneuver in various species of animal models and humans. In this study, we set out to determine the properties of these overshoots and their possible underlying mechanism. Utilizing human cardiac trabeculae, we have found that tension overshoots are temperature-dependent and that they do not occur at resting states. In addition, we have found that myosin cross-bridge cycle is vital to these overshoots as inhibition of the cycle results in the blunting of the overshoots and the magnitude of the overshoots are dependent on the level of myofilament activation. Lastly, we show that the number of cross-bridges transiently increase during tension overshoots. These findings lead us to conclude that tension overshoots are likely due to a transient enhancement of the recruitment of myosin heads into the cross-bridge cycling, regulated by the myocardium, and with potential physiological significance in determining cardiac output. We show that isolated human myocardium is capable of transiently increasing its maximal force generation capability by increasing cross-bridge recruitment following slack-restretch maneuver. This process can potentially have important implications and significance in cardiac contraction in vivo. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Method of calculation of tanks forced ventilation from the remnants of liquid products

    С. О. Пузік

    2013-07-01

    Full Text Available The advantages of gasoline compared to other petroleum products in terms of feasibility of their research. Calculations of the duration of ventilation and changes in the concentration of vapors of gasoline remains in the gas space of the vertical tank with a capacity of 1000 m3 (RUS-1000. Nomogram constructed for the quantitative forecast available liquid balances petrol A-95 and the time duration ventylyaiyi RUS-1000 from the remnants of the petrol

  10. The capacity investment decision for make-to-order production systems with demand rate control

    Bertrand, J.W.M.; Ooijen, van H.P.G.

    2012-01-01

    In this paper we study the capacity investment decision for make-to-order manufacturing firms that utilize a fixed capacity, operate in a stochastic, stationary market, and can influence their demand rate by increasing or decreasing their sales effort. We consider manufacturing situations that

  11. Capacity building to improve the Malaysian inspection and monitoring systems for aquaculture and fisheries products

    Berendsen, B.; Wegh, R.S.; Zaaijer, S.; Dijk, van J.P.; Gevers, G.J.M.

    2013-01-01

    This report describes the content, the approach used and lessons learned during the implementation of a capacity development programme to build the analytical capacity of laboratory staff of the Department of Fisheries (DoF) and the Ministry of Health (MoH) who are directly involved in the analysis

  12. RATE-DEPENDENT PULL-OUT BEARING CAPACITY OF PILES BY SIMILITUDE MODEL TESTS USING SEEPAGE FORCE

    Kato, Tatsuya; Kokusho, Takaji

    Pull-out test of model piles was conducted by varying the pull-out velocity and skin friction of piles using a seepage force similitude model test apparatus. Due to the seepage consolidation under the pressure of 150kPa, the effective stress distribution in a prototype saturated soil of 17m could be successfully reproduced in the model ground of 28cm thick, in which the pull-out tests were carried out. The pull-out load rose to a peak value at small displacement, and then decreased to a residual value. At the same time, pore pressure in the vicinity of the pile decreased due to suction near the tip and the positive dilatancy near the pile skin. The maximum pull-out load, pile axial load, side friction and the corresponding displacement increased dramatically with increasing pull-out velocity. It was found that these rate-dependent trends become more prominent with increasing skin friction.

  13. Mechanisms of force production during linear accelerations in bluegill sunfish Lepomis macrochirus

    Tytell, Eric D.; Wise, Tyler N.; Boden, Alexandra L.; Sanders, Erin K.; Schwalbe, Margot A. B.

    2016-11-01

    In nature, fish rarely swim steadily. Although unsteady behaviors are common, we know little about how fish change their swimming kinematics for routine accelerations, and how these changes affect the fluid dynamic forces and the wake produced. To study force production during acceleration, particle image velocimetry was used to quantify the wake of bluegill sunfish Lepomis macrochirus and to estimate the pressure field during linear accelerations and steady swimming. We separated "steady" and "unsteady" trials and quantified the forward acceleration using inertial measurement units. Compared to steady sequences, unsteady sequences had larger accelerations and higher body amplitudes. The wake consisted of single vortices shed during each tail movement (a '2S' wake). The structure did not change during acceleration, but the circulation of the vortices increased, resulting in larger forces. A fish swimming unsteadily produced significantly more force than the same fish swimming steadily, even when the accelerations were the same. This increase is likely due to increased added mass during unsteady swimming, as a result of the larger body amplitude. Pressure estimates suggest that the increase in force is correlated with more low pressure regions on the anterior body. This work was supported by ARO W911NF-14-1-0494 and NSF RCN-PLS 1062052.

  14. Building research capacity and productivity among advanced practice nurses: an evaluation of the Community of Practice model.

    Gullick, Janice G; West, Sandra H

    2016-03-01

    The aim of this study was to evaluate Wenger's Community of Practice as a framework for building research capacity and productivity. While research productivity is an expected domain in influential models of advanced nursing practice, internationally it remains largely unmet. Establishment of nursing research capacity precedes productivity and consequently, there is a strong imperative to identify successful capacity-building models for nursing-focussed research in busy clinical environments. Prospective, longitudinal, qualitative descriptive design was used in this study. Bruyn's participant observation framed evaluation of a Community of Practice comprising 25 advanced practice nurses. Data from focus groups, education evaluations, blog/email transcripts and field observations, collected between 2007 and 2014, were analysed using a qualitative descriptive method. The Community of Practice model invited differing levels of participation, allowed for evolution of the research community and created a rhythm of research-related interactions and enduring research relationships. Participants described the value of research for their patients and families and the significance of the developing research culture in providing richness to their practice and visibility of their work to multidisciplinary colleagues. Extensive examples of research dissemination and enrolment in doctoral programmes further confirmed this value. A Community of Practice framework is a powerful model enabling research capacity and productivity evidenced by publication. In developing a solid foundation for a nursing research culture, it should be recognized that research skills, confidence and growth develop over an extended period of time and success depends on skilled coordination and leadership. © 2015 John Wiley & Sons Ltd.

  15. Tissue advanced glycation end products are associated with diastolic function and aerobic exercise capacity in diabetic heart failure patients

    Willemsen, Suzan; Hartog, Jasper W. L.; Hummel, Yoran M.; van Ruijven, Marieke H. I.; van der Horst, Iwan C. C.; van Veldhuisen, Dirk J.; Voors, Adriaan A.

    Aims Advanced glycation end products (AGEs) are increased in patients with diabetes and are associated with diastolic dysfunction through the formation of collagen crosslinks in the heart. The association among AGEs, diastolic function, and aerobic capacity in heart failure (HF) patients with and

  16. Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS.

    Joshi, Payal; Bhoir, Suvarna; Bhagwat, A M; Vishwanath, K; Jadhav, R K

    2011-05-01

    Degradation products of itopride formed under different forced conditions have been identified using LC-PDA and LC-MS techniques. Itopride was subjected to forced degradation under the conditions of hydrolysis, photolysis, oxidation, dry and wet heat, in accordance with the International Conference on Harmonization. The stress solutions were chromatographed on reversed phase C18 (250×4.6 mm, 5 μm) column with a mobile phase methanol:water (55:45, v/v) at a detection wavelength of 215 nm. Itopride degraded in acid, alkali and oxidative stress conditions. The stability indicating method was developed and validated. The degradation pathway of the drug to products II-VIII is proposed.

  17. Air Force Policy for Advanced Education: Production of Human Capital or Cheap Signals?

    2011-01-01

    is not prima facie evidence that all on-base and distance-learning graduate programs offered to military members are devoid of any production of...then becomes whether or not most officers engaged in vol­ untary off- duty education programs do so to augment their promotion opportunities or to...their capability to perform the duties of the next rank. However, members of the board do not have information such as IQ, Air Force Officer Qualifying

  18. Tennis in hot and cool conditions decreases the rapid muscle torque production capacity of the knee extensors but not of the plantar flexors

    Girard, Olivier; Racinais, Sébastien; Périard, Julien D

    2014-01-01

    Objectives To assess the time course of changes in rapid muscle force/torque production capacity and neuromuscular activity of lower limb muscles in response to prolonged (∼2 h) match-play tennis under heat stress. Methods The rates of torque development (RTD) and electromyographic activity (EMG; ie, root mean square) rise were recorded from 0 to 30, –50, –100 and –200 ms during brief (3–5 s) explosive maximal isometric voluntary contractions (MVC) of the knee extensors (KE) and plantar flexors (PF), along with the peak RTD within the entirety of the torque-time curve. These values were recorded in 12 male tennis players before (prematch) and after (postmatch, 24 and 48 h) match-play in HOT (∼37°C) and COOL (∼22°C) conditions. Results The postmatch core temperature was greater in the HOT (∼39.4°C) vs COOL (∼38.7°C) condition (ptorque. Furthermore, the rate of KE EMG activity rise remained unchanged. Conversely, the PF contractile RTD and rate of EMG activity rise were unaffected by the exercise or environmental conditions. Conclusions In the KE, a reduction in maximal torque production capacity following prolonged match-play tennis appears to account for the decrease in the rate of torque development, independent of environmental conditions, while remaining unchanged in the PF. PMID:24668381

  19. Effects of Jaw Clenching and Jaw Alignment Mouthpiece Use on Force Production During Vertical Jump and Isometric Clean Pull.

    Allen, Charles R; Fu, Yang-Chieh; Cazas-Moreno, Vanessa; Valliant, Melinda W; Gdovin, Jacob R; Williams, Charles C; Garner, John C

    2018-01-01

    Allen, CR, Fu, Y-C, Cazas-Moreno, V, Valliant, MW, Gdovin, JR, Williams, CC, and Garner, JC. Effects of jaw clenching and jaw alignment mouthpiece use on force production during vertical jump and isometric clean pull. J Strength Cond Res 32(1): 237-243, 2018-This study examined the effects of jaw clenching, a self-adapted, jaw-repositioning mouthpiece on force production during maximum countermovement vertical jump and maximum isometric midthigh clean pull assessments in an attempt to determine any ergogenic effect attributable to clenching, jaw-repositioning mouthpiece use, or the combination of both. Thirty-six male subjects performed vertical jump and isometric clean pull assessments from a force platform under various mouthpiece and clench conditions. A 3 × 2 (mouthpiece × clench) repeated-measures analysis of variance was conducted to analyze each of the following force production variables for both assessments: peak force, normalized peak force, and rate of force development. In addition, jump height was analyzed for the vertical jump. Results revealed improvements in peak force (F1,35 = 15.84, p ≤ 0.001, (Equation is included in full-text article.)= 0.31), normalized peak force (F1,35 = 16.28, p ≤ 0.001, (Equation is included in full-text article.)= 0.32), and rate of force development (F1,35 = 12.89, p = 0.001, (Equation is included in full-text article.)= 0.27) during the isometric clean pull assessment when participants maximally clenched their jaw, regardless of mouthpiece condition. There were no statistically significant differences in jump height, peak force, normalized peak force, or rate of force development during the vertical jump for any treatment condition. This study supports previous research demonstrating that the implementation of remote voluntary contractions such as jaw clenching can lead to concurrent activation potentiation and a resulting ergogenic effect during activities involving and requiring high-force production.

  20. Assessment of wetland productive capacity from a remote-sensing-based model - A NASA/NMFS joint research project

    Butera, M. K.; Frick, A. L.; Browder, J.

    1983-01-01

    NASA and the U.S. National Marine Fisheries Service have undertaken the development of Landsat Thematic Mapper (TM) technology for the evaluation of the usefulness of wetlands to estuarine fish and shellfish production. Toward this end, a remote sensing-based Productive Capacity model has been developed which characterizes the biological and hydrographic features of a Gulf Coast Marsh to predict detrital export. Regression analyses of TM simulator data for wetland plant production estimation are noted to more accurately estimate the percent of total vegetative cover than biomass, indicating that a nonlinear relationship may be involved.

  1. Low SNR capacity for MIMO Rician and Rayleigh-product fading channels with single co-channel interferer and noise

    Zhong, Caijun

    2010-09-01

    This paper studies the ergodic capacity of multiple-input multiple-output (MIMO) systems with a single co-channel interferer in the low signal-to-noise-ratio (SNR) regime. Two MIMO models namely Rician and Rayleigh-product channels are investigated. Exact analytical expressions for the minimum energy per information bit, {Eb/N0min, and wideband slope, S0, are derived for both channels. Our results show that the minimum energy per information bit is the same for both channels while their wideband slopes differ significantly. Further, the impact of the numbers of transmit and receive antennas, the Rician K factor, the channel mean matrix and the interference-to-noise-ratio (INR) on the capacity, is addressed. Results indicate that interference degrades the capacity by increasing the required minimum energy per information bit and reducing the wideband slope. Simulation results validate our analytical results. © 2010 IEEE.

  2. Detection of charge storage on molecular thin films of tris(8-hydroxyquinoline) aluminum (Alq3) by Kelvin force microscopy: a candidate system for high storage capacity memory cells.

    Paydavosi, Sarah; Aidala, Katherine E; Brown, Patrick R; Hashemi, Pouya; Supran, Geoffrey J; Osedach, Timothy P; Hoyt, Judy L; Bulović, Vladimir

    2012-03-14

    Retention and diffusion of charge in tris(8-hydroxyquinoline) aluminum (Alq(3)) molecular thin films are investigated by injecting electrons and holes via a biased conductive atomic force microscopy tip into the Alq(3) films. After the charge injection, Kelvin force microscopy measurements reveal minimal changes with time in the spatial extent of the trapped charge domains within Alq(3) films, even for high hole and electron densities of >10(12) cm(-2). We show that this finding is consistent with the very low mobility of charge carriers in Alq(3) thin films (<10(-7) cm(2)/(Vs)) and that it can benefit from the use of Alq(3) films as nanosegmented floating gates in flash memory cells. Memory capacitors using Alq(3) molecules as the floating gate are fabricated and measured, showing durability over more than 10(4) program/erase cycles and the hysteresis window of up to 7.8 V, corresponding to stored charge densities as high as 5.4 × 10(13) cm(-2). These results demonstrate the potential for use of molecular films in high storage capacity nonvolatile memory cells. © 2012 American Chemical Society

  3. Optimal Pricing and Production Master Planning in a Multiperiod Horizon Considering Capacity and Inventory Constraints

    Neale R. Smith

    2009-01-01

    Full Text Available We formulate and solve a single-item joint pricing and master planning optimization problem with capacity and inventory constrains. The objective is to maximize profits over a discrete-time multiperiod horizon. The solution process consists of two steps. First, we solve the single-period problem exactly. Second, using the exact solution of the single-period problem, we solve the multiperiod problem using a dynamic programming approach. The solution process and the importance of considering both capacity and inventory constraints are illustrated with numerical examples.

  4. Isotope Production for Pet’s Changing Clientele: Surviving the Centrifugal Forces

    Barnhart, T. E.; Engle, J. W.; Nickles, R. J. [Department of Medical Physics, University of Wisconsin, Madison, WI, 53706 (United States)

    2009-07-01

    After thirty years of slow growth, the production of PET tracers at the University of Wisconsin has ignited, entering an exponential phase. The capacity has undergone a major boost with new facilities, but difficulties arise in trying to maintain a balance that has traditionally existed between the expectations of basic scientists using novel tracers, clinicians needing reliable supply of routine agents, and our academic mission for the training of graduate students toward their doctoral degrees. This IAEA CRP has provided a template that has assisted us in our pursuit of sustainable operation, critical for the transfer of technology to Member States with widely differing needs and resources. (author)

  5. Isotope Production for Pet’s Changing Clientele: Surviving the Centrifugal Forces

    Barnhart, T.E.; Engle, J.W.; Nickles, R.J.

    2009-01-01

    After thirty years of slow growth, the production of PET tracers at the University of Wisconsin has ignited, entering an exponential phase. The capacity has undergone a major boost with new facilities, but difficulties arise in trying to maintain a balance that has traditionally existed between the expectations of basic scientists using novel tracers, clinicians needing reliable supply of routine agents, and our academic mission for the training of graduate students toward their doctoral degrees. This IAEA CRP has provided a template that has assisted us in our pursuit of sustainable operation, critical for the transfer of technology to Member States with widely differing needs and resources. (author)

  6. Agricultural Capacity to Increase the Production of Select Fruits and Vegetables in the US: A Geospatial Modeling Analysis.

    Conrad, Zach; Peters, Christian J; Chui, Kenneth; Jahns, Lisa; Griffin, Timothy S

    2017-09-23

    The capacity of US agriculture to increase the output of specific foods to accommodate increased demand is not well documented. This research uses geospatial modeling to examine the capacity of the US agricultural landbase to increase the per capita availability of an example set of nutrient-dense fruits and vegetables. These fruits and vegetables were selected based on nutrient content and an increasing trend of domestic production and consumption. Geographic information system models were parameterized to identify agricultural land areas meeting crop-specific growing requirements for monthly precipitation and temperature; soil depth and type; cropland availability; and proximity to existing production centers. The results of these analyses demonstrate that crop production can be expanded by nearly 144,000 ha within existing national production centers, generating an additional 0.05 cup-equivalents of fruits and vegetables per capita per day, representing a 1.7% increase above current total F&V availability. Expanding the size of national crop production centers can further increase the availability of all F&V by 2.5%-5.4%, which is still less than the recommended amount. Challenges to increasing F&V production in the US include lack of labor availability, barriers to adoption among producers, and threats to crop yields from environmental concerns.

  7. RESEARCHES REGARDING THE EFFECT OF SOME BIOLOGICALLY ACTIVE PRODUCTS UPON THE GERMINATION CAPACITIES OF SMOOTH BROME SEEDS

    I. PET

    2007-05-01

    Full Text Available The carrying out of uniform forage crops represents an important technological loop for all agricultural species. The uniformity of these crops is caused especially by seed germination capacity, respectively by plant emergence capacity, depending upon the climatic and technological conditions. With regards to the researches carried out in this direction, we present here the influence exerted by some biologically-active products, used through extra-root application during plant vegetation period, upon seeds submitted to germination. The observations performed on smooth brome seeds have led to the conclusion that the per cent of germinated seeds ranges from 82%, in the untreated control variant, to 87.67% in the variant treated with the product Stimupro.

  8. Quality of handwriting: Intervention based on the variation of finger force production

    Adriano Percival Calvo

    2014-09-01

    Full Text Available Difficulties in the production of proficient handwriting can be detected early in childhood. From the control point of view, non-proficient handwriting can be explained by the difficulty in adequately activating motor synergies that give support to this motor skill. Therefore, imposing different demand on the control to the motor synergies of the fingers can generate improvement in the quality of handwriting. The goal of the present study was to verify the effects of an intervention program for children with handwriting difficulties, composed of manipulative and pre-calligraphic activities that stimulate finger motor synergies through different force production demands. Thirty-four children between 7 and 12 years of age participated in the present study. Handwriting quality was evaluated through the Minnesota Handwriting Assessment. Only the experimental group (n=18 was submitted to the intervention program developed throughout 27 sessions of 30 minutes each. The results indicate that the intervention program based on the variability of force production had a positive effect on the quality of handwriting,mainly in terms of the size of letters.

  9. Increasing cocoa productivity and farmer capacity in surrounding area of PT Kaltim Prima Coal and PT Berau Coal

    J.B.Baon

    2014-01-01

    Full Text Available Based on agro-climate factors, most of surrounding area of coal mining sites in Indonesia is suitable for cocoa cultivation. However, most of cocoa farmers in the environs of coal mining sites have little access both to new technology of cocoa cultivation and to market of their cocoa products. Therefore, productivity of cocoa farms and the income of cocoa farmers are low, which may disturb social responsibility of the coal mining companies present in their surroundings. These are the consequences of poor interaction between the government, private sector and research sector. The aim of this study is to transfer and to implement good agricultural practices of cocoa in surrounding area of mining sites of Kaltim Prima Coal (KPC and Berau Coal (BC, East Kalimantan, in order to increase farmer capacity and cocoa productivity. Indonesian Coffee and Cocoa Research Institute as the developing agent of cocoa technology has established collaboration with corporate social responsibility program of KPC (already 7 years and BC (already 2 years to improve productivity and farmer capacity of cocoa farms surroundings the two cocoa mining companies. This paper discusses the aspects of natural, economic and human resources; baseline study; technology transfers; marketing partnership; cocoa productivity; farmer income after technology implementing; study of cocoa growth on post-coal-mining. It is concluded that improvement of the cocoa productivity and farmer capacity surroundings the two mining sites associated with high adoption of technology by farmers, better access to availability of knowledge for good agricultural practices, extension officers, demonstration plots, cocoa price, and length of market chains, partnership, and competition with oil palm plantations.

  10. Vortexlet models of flapping flexible wings show tuning for force production and control

    Mountcastle, A M; Daniel, T L

    2010-01-01

    Insect wings are compliant structures that experience deformations during flight. Such deformations have recently been shown to substantially affect induced flows, with appreciable consequences to flight forces. However, there are open questions related to the aerodynamic mechanisms underlying the performance benefits of wing deformation, as well as the extent to which such deformations are determined by the boundary conditions governing wing actuation together with mechanical properties of the wing itself. Here we explore aerodynamic performance parameters of compliant wings under periodic oscillations, subject to changes in phase between wing elevation and pitch, and magnitude and spatial pattern of wing flexural stiffness. We use a combination of computational structural mechanics models and a 2D computational fluid dynamics approach to ask how aerodynamic force production and control potential are affected by pitch/elevation phase and variations in wing flexural stiffness. Our results show that lift and thrust forces are highly sensitive to flexural stiffness distributions, with performance optima that lie in different phase regions. These results suggest a control strategy for both flying animals and engineering applications of micro-air vehicles.

  11. Safety considerations for continuous hydrogen production test apparatus with capacity of 50 N-litter hydrogen per hour

    Onuki, Kaoru; Akino, Norio; Shimizu, Saburo; Nakajima, Hayato; Higashi, Shunichi; Kubo, Shinji

    2001-03-01

    Since the thermochemical hydrogen production Iodine-Sulfur process decomposes water into hydrogen and oxygen using toxic chemicals such as sulfuric acid, iodine and hydriodic acid, safety considerations are very important in its research and development. Therefore, before construction of continuous hydrogen production test apparatus with capacity of 50 N-litter hydrogen per hour, comprehensive safety considerations were carried out to examine the design and construction works of the test apparatus, and the experimental plans using the apparatus. Emphasis was given on the safety considerations on prevention of breakage of glasswares and presumable abnormalities, accidents and their countermeasures. This report summarizes the results of the considerations. (author)

  12. Mitochondrial Physiology in the Major Arbovirus Vector Aedes aegypti: Substrate Preferences and Sexual Differences Define Respiratory Capacity and Superoxide Production

    Soares, Juliana B. R. Correa; Gaviraghi, Alessandro; Oliveira, Marcus F.

    2015-01-01

    Adult females of Aedes aegypti are facultative blood sucking insects and vectors of Dengue and yellow fever viruses. Insect dispersal plays a central role in disease transmission and the extremely high energy demand posed by flight is accomplished by a very efficient oxidative phosphorylation process, which take place within flight muscle mitochondria. These organelles play a central role in energy metabolism, interconnecting nutrient oxidation to ATP synthesis, but also represent an important site of cellular superoxide production. Given the importance of mitochondria to cell physiology, and the potential contributions of this organelle for A. aegypti biology and vectorial capacity, here, we conducted a systematic assessment of mitochondrial physiology in flight muscle of young adult A. aegypti fed exclusively with sugar. This was carried out by determining the activities of mitochondrial enzymes, the substrate preferences to sustain respiration, the mitochondrial bioenergetic efficiency and capacity, in both mitochondria-enriched preparations and mechanically permeabilized flight muscle in both sexes. We also determined the substrates preferences to promote mitochondrial superoxide generation and the main sites where it is produced within this organelle. We observed that respiration in A. aegypti mitochondria was essentially driven by complex I and glycerol 3 phosphate dehydrogenase substrates, which promoted distinct mitochondrial bioenergetic capacities, but with preserved efficiencies. Respiration mediated by proline oxidation in female mitochondria was strikingly higher than in males. Mitochondrial superoxide production was essentially mediated through proline and glycerol 3 phosphate oxidation, which took place at sites other than complex I. Finally, differences in mitochondrial superoxide production among sexes were only observed in male oxidizing glycerol 3 phosphate, exhibiting higher rates than in female. Together, these data represent a significant step

  13. Examining effective factors on human forces' productivity in bureau of naval operations

    Younes Bahadori

    2015-01-01

    Full Text Available This research aims at examining effective factors on improvement of human forces' productivity and determining degree of influence and importance of each group among factors including workshop equipment and arrangement in organization, system of control and supervision on employees, degree of employees training, occupational value of employees and at last, administrating meritocracy system on improvement of human forces' productivity. Statistical population is composed of bureau of naval operations' employees in oil terminals' company in Khark, Iran. Statistical population has been 230, among which 135 people were determined as statistical sample size using Cochran formula. Survey instrument in this research has been questionnaire, according to which employees' ideas about effective factors on employees' productivity were evaluated. These questionnaires completed by people among statistical sample contain 16 close questions which were set up according to Likert 5-grade scale and were distributed as 135 numbers that after returning questionnaire, statistical analysis and data processing were accomplished. Analysis was performed in 2 descriptive and inferential statistics levels. Results of data analysis show that: A 5-fold factors under review “workshop equipment and arrangement of organization, system of control and supervision on employees, degree of employees training, occupational value of employees and administrating meritocracy related to human resources by management” have had effects on improvement of employees' productivity as average. B degree of employees training and then occupational value of employees and administrating meritocracy system have had the most influence, and workshop equipment and arrangement of organization and system of control and supervision on employees have had the least influence.

  14. Product Evaluation Task Force Phase Two report for BWR/PWR dissolver wastes

    Francis, A.J.

    1990-01-01

    It has been proposed that all Intermediate Level Wastes arising at Sellafield should be encapsulated prior to ultimate disposal. The Product Evaluation Task Force (PETF) was set up to investigate possible encapsulants and to produce an adequate data base to justify the preferred matrices. This report details the work carried out, under Phase 2 of the Product Evaluation Task Force programme, on BWR/PWR Dissolver Wastes. Three possible types of encapsulants for BWR/PWR Dissolver Wastes:- Inorganic cements, Polymer cements and Polymers are evaluated using the Kepner Tregoe decision analysis technique. This technique provides a methodology for scoring and ranking alternative options and evaluating any risks associated with an option. The analysis shows that for all four stages of waste management operations ie Storage, Transport, handling and emplacement, Disposal and Process, cement matrices are considerably superior to other potential matrices. A matrix, consisting of three parts Blast Furnace Slag (BFS) to one part Ordinary Portland Cement (OPC), is recommended for Phase 3 studies on BWR/PWR Dissolver Wastes. (author)

  15. Sprint Acceleration Mechanics: The Major Role of Hamstrings in Horizontal Force Production

    Morin, Jean-Benoît; Gimenez, Philippe; Edouard, Pascal; Arnal, Pierrick; Jiménez-Reyes, Pedro; Samozino, Pierre; Brughelli, Matt; Mendiguchia, Jurdan

    2015-01-01

    Recent literature supports the importance of horizontal ground reaction force (GRF) production for sprint acceleration performance. Modeling and clinical studies have shown that the hip extensors are very likely contributors to sprint acceleration performance. We experimentally tested the role of the hip extensors in horizontal GRF production during short, maximal, treadmill sprint accelerations. Torque capabilities of the knee and hip extensors and flexors were assessed using an isokinetic dynamometer in 14 males familiar with sprint running. Then, during 6-s sprints on an instrumented motorized treadmill, horizontal and vertical GRF were synchronized with electromyographic (EMG) activity of the vastus lateralis, rectus femoris, biceps femoris, and gluteus maximus averaged over the first half of support, entire support, entire swing and end-of-swing phases. No significant correlations were found between isokinetic or EMG variables and horizontal GRF. Multiple linear regression analysis showed a significant relationship (P = 0.024) between horizontal GRF and the combination of biceps femoris EMG activity during the end of the swing and the knee flexors eccentric peak torque. In conclusion, subjects who produced the greatest amount of horizontal force were both able to highly activate their hamstring muscles just before ground contact and present high eccentric hamstring peak torque capability. PMID:26733889

  16. Sprint acceleration mechanics: the major role of hamstrings in horizontal force production

    Jean-Benoit eMORIN

    2015-12-01

    Full Text Available Recent literature supports the importance of horizontal ground reaction force (GRF production for sprint acceleration performance. Modeling and clinical studies have shown that the hip extensors are very likely contributors to sprint acceleration performance. We experimentally tested the role of the hip extensors in horizontal GRF production during short, maximal, treadmill sprint accelerations. Torque capabilities of the knee and hip extensors and flexors were assessed using an isokinetic dynamometer in 14 males familiar with sprint running. Then, during 6-s sprints on an instrumented motorized treadmill, horizontal and vertical GRF were synchronized with electromyographic (EMG activity of the vastus lateralis, rectus femoris, biceps femoris and gluteus maximus averaged over the first half of support, entire support, entire swing and end-of-swing phases. No significant correlations were found between isokinetic or EMG variables and horizontal GRF. Multiple linear regression analysis showed a significant relationship (P = 0.024 between horizontal GRF and the combination of biceps femoris EMG activity during the end of the swing and the knee flexors eccentric peak torque. In conclusion, subjects who produced the greatest amount of horizontal force were both able to highly activate their hamstring muscles just before ground contact and present high eccentric hamstring peak torque capability.

  17. Product Evaluation Task Force Phase Two report for MEB crud/filter aid

    Francis, A.J.

    1991-01-01

    It has been proposed that all Intermediate Level Wastes arising at Sellafield should be encapsulated prior to ultimate disposal. The Product Evaluation Task Force (PETF) was set up to investigate possible encapsulants and to produce an adequate data base to justify the preferred matrices. This report details the work carried out, under Phase 2 of the Product Evaluation Task Force programme, on MEB Crud/Filter Aid. Three possible types of encapsulants for MEB Crud/Filter Aid:- Inorganic cements, Polymer cements, and Polymers are evaluated using the Kepner Tregoe decision and analysis technique. This technique provides a methodology for scoring and ranking alternative options and evaluating any risks associated with an option. The analysis shows that for all four stages of waste management operations, ie Storage, Transport, handling and emplacement, Disposal and, Process, cement matrices are considerably superior to other potential matrices. A matrix, consisting of nine parts Blast Furnace Slag (BFS) to one part Ordinary Portland Cement (OPC) is recommended as the preferred matrix for Phase 3 studies on MEB/Filter Aid. (author)

  18. ADAPTIVE CAPACITIES OF FARMERS TO CLIMATE CHANGE ADAPTATION STRATEGIES AND THEIR EFFECTS ON RICE PRODUCTION IN THE NORTHERN REGION OF GHANA

    Franklin Nantui Mabe

    2012-11-01

    Full Text Available This study estimated the adaptive capacities of farmers to climate change adaptation strategies and their effects on rice production in the Northern Region of Ghana. The adaptive capacities of rice farmers were estimated quantitatively and categorized into high, moderate and low adaptive capacities. Double logarithmic regression model of Cobb-Douglas production function was used to quantity the effects of adaptive capacities of farmers on rice production. On the average, the farmers interviewed are moderately adaptive to climate change. Also, high adaptive farmers obtain nine more bags of 50 kg bag of paddy rice than farmers with low adaptive capacities. Therefore, the more a farmer has the ability to adjust to climate change, the more the number of bags of rice he or she obtains. Rice farmers should be empowered through better extension services in order to attain high adaptive capacity status so as to help them obtain more rice output.

  19. [Nitrous oxide production by the German Armed Forces in the 20th century : History of medicine and pharmacy in the Armed Forces].

    Kronabel, D B J

    2010-03-01

    The nitrous oxide production unit of the German Armed Forces was a worldwide unique facility which was only employed in the former main medical depot at Euskirchen (nitrous oxide: medical gas which is now obsolete). The last unit was phased out in 2002 and brought to the main medical depot at Blankenburg. Unfortunately the unit is now no longer in the depot and seems to have disappeared. This article describes the nitrous oxide production process and the use of the production unit which was designed by the Socsil company of Switzerland.

  20. Four new degradation products of doxorubicin: An application of forced degradation study and hyphenated chromatographic techniques

    Dheeraj Kaushik

    2015-10-01

    Full Text Available Forced degradation study on doxorubicin (DOX was carried out under hydrolytic condition in acidic, alkaline and neutral media at varied temperatures, as well as under peroxide, thermal and photolytic conditions in accordance with International Conference on Harmonization (ICH guidelines Q1(R2. It was found extremely unstable to alkaline hydrolysis even at room temperature, unstable to acid hydrolysis at 80 °C, and to oxidation at room temperature. It degraded to four products (O-I–O-IV in oxidative condition, and to single product (A-I in acid hydrolytic condition. These products were resolved on a C8 (150 mm×4.6 mm, 5 µm column with isocratic elution using mobile phase consisting of HCOONH4 (10 mM, pH 2.5, acetonitrile and methanol (65:15:20, v/v/v. Liquid chromatography–photodiode array (LC–PDA technique was used to ascertain the purity of the products noted in LC–UV chromatogram. For their characterization, a six stage mass fragmentation (MS6 pattern of DOX was outlined through mass spectral studies in positive mode of electrospray ionization (+ESI as well as through accurate mass spectral data of DOX and the products generated through liquid chromatography–time of flight mass spectrometry (LC–MS–TOF on degraded drug solutions. Based on it, O-I–O-IV were characterized as 3-hydroxy-9-desacetyldoxorubicin-9-hydroperoxide, 1-hydroxy-9-desacetyldoxorubicin-9-hydroperoxide, 9-desacetyldoxorubicin-9-hydroperoxide and 9-desacetyldoxorubicin, respectively, whereas A-I was characterized as deglucosaminyl doxorubicin. While A-I was found to be a pharmacopoeial impurity, all oxidative products were found to be new degradation impurities. The mechanisms and pathways of degradation of doxorubicin were outlined and discussed. Keywords: Doxorubicin, TOF, Forced degradation, Liquid chromatography, Degradation product, Mass fragmentation pattern

  1. Co-gasification of black liquor and pyrolysis oil: Evaluation of blend ratios and methanol production capacities

    Andersson, Jim; Furusjö, Erik; Wetterlund, Elisabeth; Lundgren, Joakim; Landälv, Ingvar

    2016-01-01

    Highlights: • Biomethanol from co-gasified black liquor and pyrolysis oil at different capacities. • Enables higher biofuel production for given available amount of black liquor. • Opportunity for cost efficient black liquor gasification also in small pulp mills. • The methanol can be cost competitive to 2nd generation ethanol and fossil fuels. • Fewer pulp mills would need to be converted to meet given biofuel demand. - Abstract: The main aim of this study is to investigate integrated methanol production via co-gasification of black liquor (BL) and pyrolysis oil (PO), at Swedish pulp mills. The objectives are to evaluate techno-economically different blends ratios for different pulp mill capacities. Furthermore, the future methanol production potential in Sweden and overall system consequences of large-scale implementation of PO/BL co-gasification are also assessed. It is concluded that gasification of pure BL and PO/BL blends up to 50% results in significantly lower production costs than what can be achieved by gasification of unblended PO. Co-gasification with 20–50% oil addition would be the most advantageous solution based on IRR for integrated biofuel plants in small pulp mills (200 kADt/y), whilst pure black liquor gasification (BLG) will be the most advantageous alternative for larger pulp mills. For pulp mill sizes between 300 and 600 kADt/y, it is also concluded that a feasible methanol production can be achieved at a methanol market price below 100 €/MW h, for production capacities ranging between 0.9 and 1.6 TW h/y for pure BLG, and between 1.2 and 6.5 TW h/y for PO/BL co-gasification. This study also shows that by introducing PO/BL co-gasification, fewer pulp mills would need to be converted to biofuel plants than with pure BLG, to meet a certain biofuel demand for a region. Due to the technical as well as organizational complexity of the integration this may prove beneficial, and could also potentially lower the total investment

  2. Effect of dietary vitamin E on broiler meat qualities, color, water-holding capacity and shear force value, under heat stress conditions.

    Hashizawa, Yoshinori; Kubota, Masatoshi; Kadowaki, Motoni; Fujimura, Shinobu

    2013-11-01

    This study was conducted to evaluate the effect of dietary vitamin E (VE) on broiler meat quality, especially focused on PSE (pale color, soft and exudative), under chronic heat stress (HS) conditions. Twenty-eight-day-old female Ross broilers were kept in independent cages with a controlled temperature of 24°C (normal temperature: NT) or 30°C (high temperature: HT). The NT chickens were fed basal feed. The HT chickens were fed basal feed (HT) or VE (200 mg/kg) added feed (HT + E). Broilers were weighed and slaughtered at 38 days old. The breast muscle was removed immediately and then the samples were used for determination of meat color, pH, water holding capacity (WHC) and shear force value (SFV). Body weight gain and feed intake were significantly decreased in the HT and HT + E groups compared to the NT group. VE supplementation did not affect the growth performance. Chronic HS at 30°C for 10 days may cause deterioration of meat quality such as PSE. The effects of chronic HS on meat quality were most significant in the toughness of broiler breast meat. Supplementation of VE in broiler feed would be effective to prevent the extent of PSE on broiler meat by chronic HS. © 2013 Japanese Society of Animal Science.

  3. Potential Water Retention Capacity as a Factor in Silage Effluent Control: Experiments with High Moisture By-product Feedstuffs.

    Razak, Okine Abdul; Masaaki, Hanada; Yimamu, Aibibula; Meiji, Okamoto

    2012-04-01

    The role of moisture absorptive capacity of pre-silage material and its relationship with silage effluent in high moisture by-product feedstuffs (HMBF) is assessed. The term water retention capacity which is sometimes used in explaining the rate of effluent control in ensilage may be inadequate, since it accounts exclusively for the capacity of an absorbent incorporated into a pre-silage material prior to ensiling, without consideration to how much the pre-silage material can release. A new terminology, 'potential water retention capacity' (PWRC), which attempts to address this shortcoming, is proposed. Data were pooled from a series of experiments conducted separately over a period of five years using laboratory silos with four categories of agro by-products (n = 27) with differing moisture contents (highest 96.9%, lowest 78.1% in fresh matter, respectively), and their silages (n = 81). These were from a vegetable source (Daikon, Raphanus sativus), a root tuber source (potato pulp), a fruit source (apple pomace) and a cereal source (brewer's grain), respectively. The pre-silage materials were adjusted with dry in-silo absorbents consisting wheat straw, wheat or rice bran, beet pulp and bean stalks. The pooled mean for the moisture contents of all pre-silage materials was 78.3% (±10.3). Silage effluent decreased (p<0.01), with increase in PWRC of pre-silage material. The theoretical moisture content and PWRC of pre-silage material necessary to stem effluent flow completely in HMBF silage was 69.1% and 82.9 g/100 g in fresh matter, respectively. The high correlation (r = 0.76) between PWRC of ensiled material and silage effluent indicated that the latter is an important factor in silage-effluent relationship.

  4. Phenolic acids and flavonoids of peanut by-products: Antioxidant capacity and antimicrobial effects.

    de Camargo, Adriano Costa; Regitano-d'Arce, Marisa Aparecida Bismara; Rasera, Gabriela Boscariol; Canniatti-Brazaca, Solange Guidolin; do Prado-Silva, Leonardo; Alvarenga, Verônica Ortiz; Sant'Ana, Anderson S; Shahidi, Fereidoon

    2017-12-15

    Peanut skin (PS) and meal from dry-blanched peanuts (MDBP) were evaluated as sources of phenolic compounds. PS rendered the highest total phenolic content, antioxidant capacity towards ABTS radical cation, DPPH and hydroxyl radicals as well as reducing power. Phenolic acids were present in PS and MDBP whereas proanthocyanidins and monomeric flavonoids were found only in PS as identified by HPLC-DAD-ESI-MS n . Procyanidin-rich extracts prevented oxidation in non-irradiated and gamma-irradiated fish model system. Both extracts inhibited the growth of gram-positive (Bacillus cereus, Staphylococcus aureus, Listeria monocytogenes, Geobacillus stearothermophilus) and gram-negative bacteria (Pseudomonas aeruginosa, Pseudomonas fluorescens, Salmonella Enteritidis, Salmonella Typhimurium, Escherichia coli). Regardless of the strain, phenolic acid-rich extracts showed the lowest minimum inhibitory capacity (MIC); therefore presenting higher antibacterial effect. The MIC of phenolic acid-rich extracts (24-49μgphenolics/mL) was higher but comparable to Ampicillin (10μg/mL). Thus, phenolics in PS and MDBP may serve as antioxidants and antimicrobial compounds. Copyright © 2017. Published by Elsevier Ltd.

  5. The secretory products of Trichomonas vaginalis decrease fertilizing capacity of mice sperm in vitro

    Jaesook Roh

    2015-04-01

    Full Text Available Trichomonas vaginalis infection is one of the most prevalent sexually transmitted infections in humans and is now recognized as an important cause of infertility in men. There is little information about the effect of extracellular polymeric substances (EPS from T. vaginalis on sperm, but previous reports do not provide a conclusive description of the functional integrity of the sperm. To investigate the impact of EPS on the fertilizing capacity of sperm, we assessed sperm motility, acrosomal status, hypo-osmotic swelling, and in vitrofertilization rate after incubating the sperm with EPS in vitrousing mice. The incubation of sperm with EPS significantly decreased sperm motility, viability, and functional integrity in a concentration and time-dependent manner. These effects on sperm quality also resulted in a decreased fertilization rate in vitro. This is the first report that demonstrates the direct negative impact of the EPS of T. vaginalis on the fertilization rate of sperm in vitro. However, further study should be performed using human sperm to determine if EPS has similar negative impact on human sperm fertilizing capacity in vitro.

  6. The secretory products of Trichomonas vaginalis decrease fertilizing capacity of mice sperm in vitro

    Roh, Jaesook; Lim, Young-Su; Seo, Min-Young; Choi, Yuri; Ryu, Jae-Sook

    2015-01-01

    Trichomonas vaginalis infection is one of the most prevalent sexually transmitted infections in humans and is now recognized as an important cause of infertility in men. There is little information about the effect of extracellular polymeric substances (EPS) from T. vaginalis on sperm, but previous reports do not provide a conclusive description of the functional integrity of the sperm. To investigate the impact of EPS on the fertilizing capacity of sperm, we assessed sperm motility, acrosomal status, hypo-osmotic swelling, and in vitro fertilization rate after incubating the sperm with EPS in vitro using mice. The incubation of sperm with EPS significantly decreased sperm motility, viability, and functional integrity in a concentration and time-dependent manner. These effects on sperm quality also resulted in a decreased fertilization rate in vitro. This is the first report that demonstrates the direct negative impact of the EPS of T. vaginalis on the fertilization rate of sperm in vitro. However, further study should be performed using human sperm to determine if EPS has similar negative impact on human sperm fertilizing capacity in vitro. PMID:25578937

  7. Implementation of Capacity Planning Agent of Demand Responsive Planning Framework : Master’s Thesis in Production Engineering of The Royal Institute of Technology

    Juhong, Nirut

    2013-01-01

    This master’s thesis is conducted as a conclusion of Master degree of Science in Production Engineering and Management at The Royal Institute of Technology. The focus of this thesis work is to implement a Capacity planning agent. Nowadays, companies need to adapt themselves to be as responsive to customers’ demand as possible. However, the responsiveness is usually limited by the fixed capacity of the production. Evolvable Production System (EPS), motivated by the limitation mentioned above, ...

  8. The relationship between lignin peroxidase and manganese peroxidase production capacities and cultivation periods of mushrooms.

    Xu, Jian Z; Zhang, Jun L; Hu, Kai H; Zhang, Wei G

    2013-05-01

    Mushrooms are able to secrete lignin peroxidase (LiP) and manganese peroxidase (MnP), and able to use the cellulose as sources of carbon. This article focuses on the relation between peroxidase-secreting capacity and cultivation period of mushrooms with non-laccase activity. Methylene blue and methyl catechol qualitative assay and spectrophotometry quantitative assay show LiP secreting unvaryingly accompanies the MnP secreting in mushroom strains. The growth rates of hyphae are detected by detecting the dry hyphal mass. We link the peroxidase activities to growth rate of mushrooms and then probe into the relationship between them. The results show that there are close relationships between LiP- and/or MnP-secretory capacities and the cultivation periods of mushrooms. The strains with high LiP and MnP activities have short cultivation periods. However, those strains have long cultivation periods because of the low levels of secreted LiP and/or MnP, even no detectable LiP and/or MnP activity. This study provides the first evidence on the imitate relation between the level of secreted LiP and MnP activities and cultivation periods of mushrooms with non-laccase activity. Our study has significantly increased the understanding of the role of LiP and MnP in the growth and development of mushrooms with non-laccase activity. © 2012 The Authors. Microbial Biotechnology © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  9. Natural forcings on a transformed territory overshoot thresholds of primary productivity in the Guadalquivir estuary

    Ruiz, J.; Macías, D.; Navarro, G.

    2017-09-01

    A three year-long quasi continuum sampling dataset on the Guadalquivir estuary water quality was used to assess the role of light availability on its biological production. We found that inorganic nutrients within the estuary are very high (with mean values for inorganic nitrogen and phosphorous of 285 and 2.4 μM respectively) while phytoplankton biomass remains low most of the time (with a mean value of 2.6 mg/m3). A strong relationship between phytoplankton biomass and water turbidity was found indicating that, indeed, light availability is the major constraint of primary production in this system. Most of the time this limitation of primary production is not associated to enhanced turbidity connected to fresh water inputs. Instead, our data indicate that, independently of freshwater inputs, the photosynthesis is restricted by tidal forcings enhancing turbidity in an estuary that has been highly modified. Our results match with classical theories on the functioning of well-mixed, estuarine ecosystems as well as with recent modeling exercises. We also discuss the potential impacts of this particular characteristic of some estuarine systems for their management and regulatory control.

  10. Effect of the ion force on the hydrolysis constants and of the solubility product of Europium

    Jimenez R, M.; Ramirez G, J.J.; Solache R, M.; Rojas H, A.

    2003-01-01

    A study on the behavior of the first hydrolysis constant β Eu,H l-0 and the constant of the solubility product Kps of the europium in front of the changes of the ion force: 0. 02 M, 0.1 M, 0.7M, 2M, 3M and 4M of sodium perchlorate, at 303 K. Experimentally the potentiometry and also radioactivity measures its were used. The specific interaction of ions theory (SIT) of Bronsted-Guggenheim-Scatchard allows the extrapolation of the values to infinite dilution and the results were: log β Eu,H l-0 = -7 36 and log K sp l-0 = -24. 68. A discussion of the group of results with the data of the literature is presented. (Author)

  11. Factors Affecting Aerosol Radiative Forcing from Both Production-based and Consumption-based View

    Wang, J.; Lin, J.; Ni, R.

    2017-12-01

    Aerosol radiative forcing (RF) is determined by emissions and various chemical-transport-radiative processes in the atmosphere, a multi-factor problem whose individual contributors have not been well quantified. This problem becomes more complicated when taking into account the role of international trade, which means reallocated aerosol RF due to separation of regions producing goods and emissions and regions consuming those goods. Here we analyze major factors affecting RF of secondary inorganic aerosols (SIOAs, including sulfate, nitrate and ammonium), primary organic aerosol (POA) and black carbon (BC), extending the work of Lin et al. (2016, Nature Geoscience). We contrast five factors determining production-based (RFp, due to a region's production of goods) and consumption-based (RFc, due to a region's consumption) forcing by 11 major regions, including population size, per capita output, emission intensity (emission per output), chemical efficiency (mass per unit emission) and radiative efficiency (RF per unit mass). Comparing across the 11 regions, East Asia produces the strongest RFp and RFc of SIOA and BC and the second largest RFp and RFc of POA primarily due to its high emission intensity. Although Middle East and North Africa has low emissions, its RFp is strengthened by its largest chemical efficiency for POA and BC and second largest chemical efficiency for SIOA. However, RFp of South-East Asia and Pacific is greatly weakened by its lowest chemical efficiency. Economic trade means that net importers (Western Europe, North America and Pacific OECD) have higher RFc than RFp by 50-100%. And such forcing difference is mainly due to the high emission intensity of the exporters supplying these regions. For North America, SIOA's RFc is 50% stronger than RFp, for that emission intensity of SIOA is 5.2 times in East Asia and 2.5 times in Latin America and Caribbean compared with that in North America, and the chemical efficiency in the top four exporters are

  12. Inhibition of the vitamin B12 binding capacity of proteins by the hydrolysis product of cyclophosphamide

    Fenrych, W.; Ignatowicz, E.; Szczodrowska, E.

    1993-01-01

    The inhibitory effect of cyclophosphamide hydrolysis product (CPHP) on vitamin B 12 binding ability to proteins has been established. The ester N-(2-chloroethyl)-N'-(3-phosphopropyl)-etheylenediamine hydrochloride is probably responsible, in vitro, for blocking the protein binding sites. Preincubation of proteins with vitamin B 12 prevents the inhibitory effect of CPHP. (au)

  13. 78 FR 38055 - Building Research Capacity in Global Tobacco Product Regulation Program (U18)

    2013-06-25

    ... brand and subbrand (sections 904, 915 of the FD&C Act) (21 U.S.C. 387d, 387o). Please visit http://www... science. CTP's strategic public health goals include: Decreasing initiation of tobacco product use... Control Act; (3) plan, build, adapt, or expand data collection/information sharing mechanisms, management...

  14. Leader-follower Game in VMI System with Limited Production Capacity Considering Wholesale and Retail Prices

    Y. Yu (Yugang); L. Liang (Liming); G.Q. Huang (George)

    2006-01-01

    textabstractVMI (Vendor Managed Inventory) is a widely used cooperative inventory policy in supply chains in which each enterprise has its autonomy in pricing. This paper discusses a leader-follower Stackelberg game in a VMI supply chain where the manufacturer, as a leader, produces a single product

  15. Production Decision Based on Discounted Price and Delivery Frequency for Garment Original Equipment Manufacturer with Constrained Capacity

    HUO Yanfang; GU Yajie; HAN Lin; WANG Xize

    2017-01-01

    Original equipment manufacturers (OEM) have never been so important and powerful as it is today in garment manufacturing industry.The OEM supplier's production decisions always have a great impact on the market performance and the profits of a garment brand manufacturer.With constrained capacity and multiply buyers,how to make reasonable production decisions is an urgent problem for OEM suppliers.A price discount model with a single OEM supplier and two buyers is proposed to deal with the problem.Based on this model,the OEM supplier could satisfy buyers' demands and guarantee their profits as well through adjusting price and delivery frequency.A numerical example validates the validity of the model.

  16. Pseudomonas pseudoalcaligenes CECT5344, a cyanide-degrading bacterium with by-product (polyhydroxyalkanoates) formation capacity.

    Manso Cobos, Isabel; Ibáñez García, María Isabel; de la Peña Moreno, Fernando; Sáez Melero, Lara Paloma; Luque-Almagro, Víctor Manuel; Castillo Rodríguez, Francisco; Roldán Ruiz, María Dolores; Prieto Jiménez, María Auxiliadora; Moreno Vivián, Conrado

    2015-06-10

    Cyanide is one of the most toxic chemicals produced by anthropogenic activities like mining and jewelry industries, which generate wastewater residues with high concentrations of this compound. Pseudomonas pseudoalcaligenes CECT5344 is a model microorganism to be used in detoxification of industrial wastewaters containing not only free cyanide (CN(-)) but also cyano-derivatives, such as cyanate, nitriles and metal-cyanide complexes. Previous in silico analyses suggested the existence of genes putatively involved in metabolism of short chain length (scl-) and medium chain length (mcl-) polyhydroxyalkanoates (PHAs) located in three different clusters in the genome of this bacterium. PHAs are polyesters considered as an alternative of petroleum-based plastics. Strategies to optimize the bioremediation process in terms of reducing the cost of the production medium are required. In this work, a biological treatment of the jewelry industry cyanide-rich wastewater coupled to PHAs production as by-product has been considered. The functionality of the pha genes from P. pseudoalcaligenes CECT5344 has been demonstrated. Mutant strains defective in each proposed PHA synthases coding genes (Mpha(-), deleted in putative mcl-PHA synthases; Spha(-), deleted in the putative scl-PHA synthase) were generated. The accumulation and monomer composition of scl- or mcl-PHAs in wild type and mutant strains were confirmed by gas chromatography-mass spectrometry (GC-MS). The production of PHAs as by-product while degrading cyanide from the jewelry industry wastewater was analyzed in batch reactor in each strain. The wild type and the mutant strains grew at similar rates when using octanoate as the carbon source and cyanide as the sole nitrogen source. When cyanide was depleted from the medium, both scl-PHAs and mcl-PHAs were detected in the wild-type strain, whereas scl-PHAs or mcl-PHAs were accumulated in Mpha(-) and Spha(-), respectively. The scl-PHAs were identified as homopolymers of 3

  17. Surfactins in Natto: The Surfactin Production Capacity of the Starter Strains and the Actual Surfactin Contents in the Products

    Juola, Mari; Kinnunen, Kristiina; Nielsen, Kristian Fog

    2014-01-01

    product, natto, were isolated in order to clarify their potential to produce the suspect lipopeptides. The isolated bacilli were characterized as Bacillus subtilis. They were b-hemolytic and gave a positive signal in the PCR screen for genes associated with surfactin production, and their culture extracts...... were cytotoxic to boar sperm cells. Organic extracts of both Bacillus cultures and the natto samples were analyzed for their surfactin content using ultrahigh-performance liquid chromatography with high-resolution mass spectrometry. All the strains proved to be surfactin producers (15 to 39 mg....../ml culture medium); the natto samples contained as much as 2.2 mg g21 of surfactins. This means that consumers can ingest at least approximately 80 to 100 mg of surfactins per single 50-g natto serving apparently without suffering any ill effects, indicating a very low human toxicity....

  18. Potential Water Retention Capacity as a Factor in Silage Effluent Control: Experiments with High Moisture By-product Feedstuffs

    Razak, Okine Abdul; Masaaki, Hanada; Yimamu, Aibibula; Meiji, Okamoto

    2012-01-01

    The role of moisture absorptive capacity of pre-silage material and its relationship with silage effluent in high moisture by-product feedstuffs (HMBF) is assessed. The term water retention capacity which is sometimes used in explaining the rate of effluent control in ensilage may be inadequate, since it accounts exclusively for the capacity of an absorbent incorporated into a pre-silage material prior to ensiling, without consideration to how much the pre-silage material can release. A new terminology, ‘potential water retention capacity’ (PWRC), which attempts to address this shortcoming, is proposed. Data were pooled from a series of experiments conducted separately over a period of five years using laboratory silos with four categories of agro by-products (n = 27) with differing moisture contents (highest 96.9%, lowest 78.1% in fresh matter, respectively), and their silages (n = 81). These were from a vegetable source (Daikon, Raphanus sativus), a root tuber source (potato pulp), a fruit source (apple pomace) and a cereal source (brewer’s grain), respectively. The pre-silage materials were adjusted with dry in-silo absorbents consisting wheat straw, wheat or rice bran, beet pulp and bean stalks. The pooled mean for the moisture contents of all pre-silage materials was 78.3% (±10.3). Silage effluent decreased (p<0.01), with increase in PWRC of pre-silage material. The theoretical moisture content and PWRC of pre-silage material necessary to stem effluent flow completely in HMBF silage was 69.1% and 82.9 g/100 g in fresh matter, respectively. The high correlation (r = 0.76) between PWRC of ensiled material and silage effluent indicated that the latter is an important factor in silage-effluent relationship. PMID:25049587

  19. Potential Water Retention Capacity as a Factor in Silage Effluent Control: Experiments with High Moisture By-product Feedstuffs

    Okine Abdul Razak

    2012-04-01

    Full Text Available The role of moisture absorptive capacity of pre-silage material and its relationship with silage effluent in high moisture by-product feedstuffs (HMBF is assessed. The term water retention capacity which is sometimes used in explaining the rate of effluent control in ensilage may be inadequate, since it accounts exclusively for the capacity of an absorbent incorporated into a pre-silage material prior to ensiling, without consideration to how much the pre-silage material can release. A new terminology, ‘potential water retention capacity’ (PWRC, which attempts to address this shortcoming, is proposed. Data were pooled from a series of experiments conducted separately over a period of five years using laboratory silos with four categories of agro by-products (n = 27 with differing moisture contents (highest 96.9%, lowest 78.1% in fresh matter, respectively, and their silages (n = 81. These were from a vegetable source (Daikon, Raphanus sativus, a root tuber source (potato pulp, a fruit source (apple pomace and a cereal source (brewer’s grain, respectively. The pre-silage materials were adjusted with dry in-silo absorbents consisting wheat straw, wheat or rice bran, beet pulp and bean stalks. The pooled mean for the moisture contents of all pre-silage materials was 78.3% (±10.3. Silage effluent decreased (p<0.01, with increase in PWRC of pre-silage material. The theoretical moisture content and PWRC of pre-silage material necessary to stem effluent flow completely in HMBF silage was 69.1% and 82.9 g/100 g in fresh matter, respectively. The high correlation (r = 0.76 between PWRC of ensiled material and silage effluent indicated that the latter is an important factor in silage-effluent relationship.

  20. Evidence of circadian rhythm, oxygen regulation capacity, metabolic repeatability and positive correlations between forced and spontaneous maximal metabolic rates in lake sturgeon Acipenser fulvescens.

    Jon C Svendsen

    Full Text Available Animal metabolic rate is variable and may be affected by endogenous and exogenous factors, but such relationships remain poorly understood in many primitive fishes, including members of the family Acipenseridae (sturgeons. Using juvenile lake sturgeon (Acipenser fulvescens, the objective of this study was to test four hypotheses: 1 A. fulvescens exhibits a circadian rhythm influencing metabolic rate and behaviour; 2 A. fulvescens has the capacity to regulate metabolic rate when exposed to environmental hypoxia; 3 measurements of forced maximum metabolic rate (MMR(F are repeatable in individual fish; and 4 MMR(F correlates positively with spontaneous maximum metabolic rate (MMR(S. Metabolic rates were measured using intermittent flow respirometry, and a standard chase protocol was employed to elicit MMR(F. Trials lasting 24 h were used to measure standard metabolic rate (SMR and MMR(S. Repeatability and correlations between MMR(F and MMR(S were analyzed using residual body mass corrected values. Results revealed that A. fulvescens exhibit a circadian rhythm in metabolic rate, with metabolism peaking at dawn. SMR was unaffected by hypoxia (30% air saturation (O(2sat, demonstrating oxygen regulation. In contrast, MMR(F was affected by hypoxia and decreased across the range from 100% O(2sat to 70% O(2sat. MMR(F was repeatable in individual fish, and MMR(F correlated positively with MMR(S, but the relationships between MMR(F and MMR(S were only revealed in fish exposed to hypoxia or 24 h constant light (i.e. environmental stressor. Our study provides evidence that the physiology of A. fulvescens is influenced by a circadian rhythm and suggests that A. fulvescens is an oxygen regulator, like most teleost fish. Finally, metabolic repeatability and positive correlations between MMR(F and MMR(S support the conjecture that MMR(F represents a measure of organism performance that could be a target of natural selection.

  1. Geographic variation in Chinese children' forced vital capacity and its association with long-term exposure to local PM10: a national cross-sectional study.

    Wang, Hai-Jun; Li, Qin; Guo, Yuming; Song, Jie-Yun; Wang, Zhiqiang; Ma, Jun

    2017-10-01

    The purpose of this study was to estimate the association between Chinese children's forced vital capacity (FVC) and particulate matter with aerodynamic diameter ≤10 μm (PM 10 ). The FVC data of 71,763 children aged 7 to 18 was collected from 2010 Chinese National Survey on Students' Construction and Health (CNSSCH). The local annual average concentration of PM 10 , relative humidity, ambient temperature, and other air pollutant data of 30 cities was collected from China Meteorological Administration and Ministry of Environment Protection of China. Then, we used generalized additive model (GAM) to estimate the association between children's FVC and PM 10 . The obvious geographic variation in FVC was found in children of 30 Chinese cities ranging from 1647 ml in Xining to 2571 ml in Beijing. The annual average concentration of PM 10 was also different, ranging from 40 μg/m 3 in Haikou to 155 μg/m 3 in Lanzhou. After adjusted individual characteristics, socioeconomic conditions, ambient temperature, relative humidity, and other air pollutants (e.g., NO 2 and SO 2 ) in the generalized additive model, we found that the increase of PM 10 was associated with decrease of FVC in Chinese children. A 10-μg/m 3 increase of PM 10 was associated with 1.33-ml decrease in FVC (95% confidence interval: -2.18 to -0.47). We also found a larger effect estimate of PM 10 on FVC in boys than that in girls. Consistent associations were found in both physically inactive and active children. The increase of PM 10 was associated with decrease of children's FVC. We should develop proper public health policy to protect children's respiratory health during growth and development in polluted areas.

  2. Development of a process for high capacity arc heater production of silicon for solar arrays

    Meyer, T. N.

    1980-01-01

    A high temperature silicon production process using existing electric arc heater technology is discussed. Silicon tetrachloride and a reductant, liquid sodium, were injected into an arc heated mixture of hydrogen and argon. Under these high temperature conditions, a very rapid reaction occurred, yielding silicon and gaseous sodium chloride. Techniques for high temperature separation and collection of the molten silicon were developed. The desired degree of separation was not achieved. The electrical, control and instrumentation, cooling water, gas, SiCl4, and sodium systems are discussed. The plasma reactor, silicon collection, effluent disposal, the gas burnoff stack, and decontamination and safety are also discussed. Procedure manuals, shakedown testing, data acquisition and analysis, product characterization, disassembly and decontamination, and component evaluation are reviewed.

  3. The Synthesis of 58co-Naphthenate Complex Compound for Evaluation of Oil well Production Capacity

    Duyeh Setiawan; Marlina

    2009-01-01

    The nuclear technique using radioisotope as a tracer in oil industry has assisted to solve the degradation of oil production. Usually, the degradation of oil production in well caused by the formation changing of hydrostatic pressure of the oil layer in the well. This problem could be evaluated by injection of water to oil well, for recovering this hydrostatic pressure. The watcher of the water injection success is done by the way of nuclear technique radioactive tracer systems, applied radioisotope having short half life and low gamma radiation energy. Radioisotope cobalt-58 in the complex form with naphthenate ( 58 Co-naphthenate ) often used as the tracer in the water injection technique. The tracer 58 Co-naphthenate relatively easy to synthesis and radioisotope 58 Co has half life 70.86 days and gamma energy was 0.811 Me v. The synthesis method of 58 Co-naphthenate route has been carried out by mixing of 58 CoCl 2 radioisotope solution with sodium naphthenate (C 5 H 9 CH 2 COONa) in the optimum condition. The results shows that the optimal mole ratio of cobalt-58 and naphthenate was 1:6 which produced 87,38 % of ren dement and 82,5 % of efficiency labelling. This synthesis technique was made permanent procedure for making of 58 Co-naphthenate complex as radioactive tracer in service of radioisotope production especially industrial area. (author)

  4. Strengthening Knowledge Co-Production Capacity: Examining Interest in Community-University Partnerships

    Kathleen P. Bell

    2013-09-01

    Full Text Available Building successful, enduring research partnerships is essential for improving links between knowledge and action to address sustainability challenges. Communication research can play a critical role in fostering more effective research partnerships, especially those concerned with knowledge co-production processes. This article focuses on community-university research partnerships and factors that influence participation in the co-production process. We identify specific pathways for improving partnership development through a prospective analytical approach that examines community officials’ interest in partnering with university researchers. Using survey responses from a statewide sample of Maine municipal officials, we conduct a statistical analysis of community-university partnership potential to test a conceptual model of partnership interest grounded in natural resource management theory and environmental communication. Our findings both support and advance prior research on collaborations. Results reveal that belief in the helpfulness of the collaborator to solve problems, institutional proximity, familiarity, perceived problem severity and problem type and trust influence interest in developing community-university partnerships. These findings underscore the benefits of proactively assessing partnership potential prior to forming partnerships and the important roles for communication research within sustainability science, especially with regard to strengthening partnership formation and knowledge co-production processes.

  5. UN-ECE task force: 'by-product utilization from stationary installations'

    Hackl, A. E.; Zehetner, G.

    1996-09-01

    The task force has concluded as followed: Major sources of by-products considered in this report from stationary installations are large scale firing installations, waste incineration, upgrading processes and utilization in iron and steel, aluminium and copper industry, and the pulp and paper industry. The share of each sector source to the total amount of by-products generated differs significantly in the participating countries. State of the art processes as described in the report take account of the need for integrated pollution prevention and control. In particular the requirements set out in the Convention on Long Range Transboundary Air Pollution can still be satisfied when applying these state of the art processes. The report shows that a number of techniques for avoidance, reduction and/or utilization of by-products are in commercial operation in the branches discussed. They can therefore be considered to be best available. For some special by-products technical processes for the treatment are still in development and are not yet state-of-the-art. The implementation of the already proven techniques varies considerably in the different ECE-countries. This is mainly due to the following circumstances: differences in the design and stringency of legal regulations, availability of landfilling sites, costs of disposal, differences in industrial structure. Problems with by-product utilization originate mainly from: a) from a loss of international competitiveness of the respective industrial sector, if the reduction of the amount of by-products or their utilization leads to higher costs than conventional processes; b) from quality standards for materials which are inadequate for secondary raw materials thus creating acceptance problems of these materials. C) In some cases incineration and/or thermal recycling processes generate PCDD/F. quantities produces may be capable of reduction by means of process modification. If, however PCDD/F is released to the

  6. Uranium supply/demand projections to 2030 in the OECD/NEA-IAEA ''Red Book''. Nuclear growth projections, global uranium exploration, uranium resources, uranium production and production capacity

    Vance, Robert

    2009-01-01

    World demand for electricity is expected to continue to grow rapidly over the next several decades to meet the needs of an increasing population and economic growth. The recognition by many governments that nuclear power can produce competitively priced, base load electricity that is essentially free of greenhouse gas emissions, combined with the role that nuclear can play in enhancing security of energy supplies, has increased the prospects for growth in nuclear generating capacity. Since the mid-1960s, with the co-operation of their member countries and states, the OECD Nuclear Energy Agency (NEA) and the International Atomic Energy Agency (IAEA) have jointly prepared periodic updates (currently every 2 years) on world uranium resources, production and demand. These updates have been published by the OECD/NEA in what is commonly known as the ''Red Book''. The 2007 edition replaces the 2005 edition and reflects information current as of 1 st January 2007. Uranium 2007: Resources, Production and Demand presents, in addition to updated resource figures, the results of a recent review of world uranium market fundamentals and provides a statistical profile of the world uranium industry. It contains official data provided by 40 countries (and one Country Report prepared by the IAEA Secretariat) on uranium exploration, resources, production and reactor-related requirements. Projections of nuclear generating capacity and reactor-related uranium requirements to 2030 as well as a discussion of long-term uranium supply and demand issues are also presented. (orig.)

  7. Portfolio theory of optimal isometric force production: Variability predictions and nonequilibrium fluctuation-dissipation theorem

    Frank, T.D.; Patanarapeelert, K.; Beek, P.J.

    2008-01-01

    We derive a fundamental relationship between the mean and the variability of isometric force. The relationship arises from an optimal collection of active motor units such that the force variability assumes a minimum (optimal isometric force). The relationship is shown to be independent of the

  8. The Effects of Cryotherapy on Knee Joint Position Sense and Force Production Sense in Healthy Individuals

    Furmanek Mariusz P.

    2018-03-01

    Full Text Available The proprioceptive information received from mechanoreceptors is potentially responsible for controlling the joint position and force differentiation. However, it is unknown whether cryotherapy influences this complex mechanism. Previously reported results are not universally conclusive and sometimes even contradictory. The main objective of this study was to investigate the impact of local cryotherapy on knee joint position sense (JPS and force production sense (FPS. The study group consisted of 55 healthy participants (age: 21 ± 2 years, body height: 171.2 ± 9 cm, body mass: 63.3 ± 12 kg, BMI: 21.5 ± 2.6. Local cooling was achieved with the use of gel-packs cooled to -2 ± 2.5°C and applied simultaneously over the knee joint and the quadriceps femoris muscle for 20 minutes. JPS and FPS were evaluated using the Biodex System 4 Pro apparatus. Repeated measures analysis of variance (ANOVA did not show any statistically significant changes of the JPS and FPS under application of cryotherapy for all analyzed variables: the JPS’s absolute error (p = 0.976, its relative error (p = 0.295, and its variable error (p = 0.489; the FPS’s absolute error (p = 0.688, its relative error (p = 0.193, and its variable error (p = 0.123. The results indicate that local cooling does not affect proprioceptive acuity of the healthy knee joint. They also suggest that local limited cooling before physical activity at low velocity did not present health or injury risk in this particular study group.

  9. The Effects of Cryotherapy on Knee Joint Position Sense and Force Production Sense in Healthy Individuals

    Furmanek, Mariusz P.; Słomka, Kajetan J.; Sobiesiak, Andrzej; Rzepko, Marian; Juras, Grzegorz

    2018-01-01

    Abstract The proprioceptive information received from mechanoreceptors is potentially responsible for controlling the joint position and force differentiation. However, it is unknown whether cryotherapy influences this complex mechanism. Previously reported results are not universally conclusive and sometimes even contradictory. The main objective of this study was to investigate the impact of local cryotherapy on knee joint position sense (JPS) and force production sense (FPS). The study group consisted of 55 healthy participants (age: 21 ± 2 years, body height: 171.2 ± 9 cm, body mass: 63.3 ± 12 kg, BMI: 21.5 ± 2.6). Local cooling was achieved with the use of gel-packs cooled to -2 ± 2.5°C and applied simultaneously over the knee joint and the quadriceps femoris muscle for 20 minutes. JPS and FPS were evaluated using the Biodex System 4 Pro apparatus. Repeated measures analysis of variance (ANOVA) did not show any statistically significant changes of the JPS and FPS under application of cryotherapy for all analyzed variables: the JPS’s absolute error (p = 0.976), its relative error (p = 0.295), and its variable error (p = 0.489); the FPS’s absolute error (p = 0.688), its relative error (p = 0.193), and its variable error (p = 0.123). The results indicate that local cooling does not affect proprioceptive acuity of the healthy knee joint. They also suggest that local limited cooling before physical activity at low velocity did not present health or injury risk in this particular study group. PMID:29599858

  10. Development of a Process for a High Capacity Arc Heater Production of Silicon for Solar Arrays

    Reed, W. H.

    1979-01-01

    A program was established to develop a high temperature silicon production process using existing electric arc heater technology. Silicon tetrachloride and a reductant (sodium) are injected into an arc heated mixture of hydrogen and argon. Under these high temperature conditions, a very rapid reaction is expected to occur and proceed essentially to completion, yielding silicon and gaseous sodium chloride. Techniques for high temperature separation and collection were developed. Included in this report are: test system preparation; testing; injection techniques; kinetics; reaction demonstration; conclusions; and the project status.

  11. Surfactins in natto: the surfactin production capacity of the starter strains and the actual surfactin contents in the products.

    Juola, Mari; Kinnunen, Kristiina; Nielsen, Kristian Fog; von Wright, Atte

    2014-12-01

    Surfactin-type lipopeptides are suspected of being implicated in the rare food poisonings caused by Bacillus species outside the Bacillus cereus cluster. In order to get information on surfactin levels in actual human foods, bacilli from three commercial samples of a Japanese traditional bean product, natto, were isolated in order to clarify their potential to produce the suspect lipopeptides. The isolated bacilli were characterized as Bacillus subtilis. They were β-hemolytic and gave a positive signal in the PCR screen for genes associated with surfactin production, and their culture extracts were cytotoxic to boar sperm cells. Organic extracts of both Bacillus cultures and the natto samples were analyzed for their surfactin content using ultrahigh-performance liquid chromatography with high-resolution mass spectrometry. All the strains proved to be surfactin producers (15 to 39 μg/ml culture medium); the natto samples contained as much as 2.2 mg g(-1) of surfactins. This means that consumers can ingest at least approximately 80 to 100 mg of surfactins per single 50-g natto serving apparently without suffering any ill effects, indicating a very low human toxicity.

  12. Analysis of 99Mo Production Capacity in Uranyl Nitrate Aqueous Homogeneous Reactor using ORIGEN and MCNP

    A. Isnaeni

    2014-04-01

    Full Text Available 99mTc is a very useful radioisotope in medical diagnostic procedure. 99mTc is produced from 99Mo decay. Currently, most of 99Mo is produced by irradiating 235U in the nuclear reactor. 99Mo mostly results from the fission reaction of 235U targets with a fission yield about 6.1%. A small additional amount is created from 98Mo neutron activation. Actually 99Mo is also created in the reactor fuel, but usually we do not extract it. The fuel will become spent fuel which is a highly radioactive waste. 99Mo production system in the aqueous homogeneous reactor offers a better method, because all of the 99Mo can be extracted from the fuel solution. Fresh reactor fuel solution consists of uranyl nitrate dissolved in water. There is no separation of target and fuel in an aqueous homogeneous reactor where target and fuel become one liquid solution, and there is no spent fuel generated from this reactor. Simulation of the extraction process is performed while reactor in operation (without reactor shutdown. With an extraction flow rate of 3.6 L/h, after 43 hours of reactor operation the production of 99Mo is relatively constant at about 98.6 curie/hour

  13. The Use of Lean Six Sigma Methodology in Increasing Capacity of a Chemical Production Facility at DSM.

    Meeuwse, Marco

    2018-03-30

    Lean Six Sigma is an improvement method, combining Lean, which focuses on removing 'waste' from a process, with Six Sigma, which is a data-driven approach, making use of statistical tools. Traditionally it is used to improve the quality of products (reducing defects), or processes (reducing variability). However, it can also be used as a tool to increase the productivity or capacity of a production plant. The Lean Six Sigma methodology is therefore an important pillar of continuous improvement within DSM. In the example shown here a multistep batch process is improved, by analyzing the duration of the relevant process steps, and optimizing the procedures. Process steps were performed in parallel instead of sequential, and some steps were made shorter. The variability was reduced, giving the opportunity to make a tighter planning, and thereby reducing waiting times. Without any investment in new equipment or technical modifications, the productivity of the plant was improved by more than 20%; only by changing procedures and the programming of the process control system.

  14. Capacity optimization and scheduling of a multiproduct manufacturing facility for biotech products.

    Shaik, Munawar A; Dhakre, Ankita; Rathore, Anurag S; Patil, Nitin

    2014-01-01

    A general mathematical framework has been proposed in this work for scheduling of a multiproduct and multipurpose facility involving manufacturing of biotech products. The specific problem involves several batch operations occurring in multiple units involving fixed processing time, unlimited storage policy, transition times, shared units, and deterministic and fixed data in the given time horizon. The different batch operations are modeled using state-task network representation. Two different mathematical formulations are proposed based on discrete- and continuous-time representations leading to a mixed-integer linear programming model which is solved using General Algebraic Modeling System software. A case study based on a real facility is presented to illustrate the potential and applicability of the proposed models. The continuous-time model required less number of events and has a smaller problem size compared to the discrete-time model. © 2014 American Institute of Chemical Engineers.

  15. Biochar characteristics produced from food-processing products and their sorptive capacity for mercury and phenanthrene

    Fotopoulou, Kalliopi N.; Karapanagioti, Hrissi K.; Manariotis, Ioannis D.

    2015-04-01

    Various organic-rich wastes including wood chips, animal manure, and crop residues have been used for biochar production. Biochar is used as an additive to soils to sequester carbon and improve soil fertility but its use as a sorbent for environmental remediation processes is gaining increased attention. Surface properties such as point of zero charge, surface area and pore volume, surface topography, surface functional groups and acid-base behavior are important factors, which affect sorption efficiency. Understanding the surface alteration of biochars increases our understanding of the pollutant-sorbent interaction. The scope of the present work was to evaluate the effect of key characteristics of biochars on their sorptive properties. Raw materials for biochar production were evaluated including byproducts from brewering, coffee, wine, and olive oil industry. The charring process was performed at different temperatures under limited-oxygen conditions using specialized containers. The surface area, the pore volume, and the average pore size of the biochars were determined. Open surface area and micropore volume were determined using t-plot method and Harkins & Jura equation. Raw food-processing waste demonstrates low surface area that increases by 1 order of magnitude by thermal treatment up to 750oC. At temperatures from 750 up to 900oC, pyrolysis results to biochars with surface areas 210-700 m2/g. For the same temperature range, a high percentage (46 to73%) of the pore volume of the biochars is due to micropores. Positive results were obtained when high surface area biochars were tested for their ability to remove organic (i.e. phenanthrene) and inorganic (i.e. mercury) compounds from aqueous solutions. All these properties point to new materials that can effectively be used for environmental remediation.

  16. Carrying Capacity

    Schroll, Henning; Andersen, Jan; Kjærgård, Bente

    2012-01-01

    A spatial planning act was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive....../cities. Four different sectors (water, food production, waste, and forests) were selected as core areas for decentralised spatial planning. Indicators for SCC and ACC were identified and assessed with regard to relevance and quantifiability. For each of the indicators selected, a legal threshold or guiding...... was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive carrying capacity (SCC) and assimilative...

  17. Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins.

    Takshak, Anjneya; Kunwar, Ambarish

    2016-05-01

    Many cellular processes are driven by collective forces generated by a team consisting of multiple molecular motor proteins. One aspect that has received less attention is the detachment rate of molecular motors under mechanical force/load. While detachment rate of kinesin motors measured under backward force increases rapidly for forces beyond stall-force; this scenario is just reversed for non-yeast dynein motors where detachment rate from microtubule decreases, exhibiting a catch-bond type behavior. It has been shown recently that yeast dynein responds anisotropically to applied load, i.e. detachment rates are different under forward and backward pulling. Here, we use computational modeling to show that these anisotropic detachment rates might help yeast dynein motors to improve their collective force generation in the absence of catch-bond behavior. We further show that the travel distance of cargos would be longer if detachment rates are anisotropic. Our results suggest that anisotropic detachment rates could be an alternative strategy for motors to improve the transport properties and force production by the team. © 2016 The Protein Society.

  18. Properties and Antioxidant Capacity of Anchovy (Engraulis encrasicholus) By-Product Protein Films Containing Thyme Essential Oil.

    Tural, Serpil; Turhan, Sadettin

    2017-03-01

    In this study, some properties and antioxidant capacity of anchovy ( Engraulis encrasicholus ) by-product protein films with added 0.5, 1.0 and 1.5% of thyme essential oil were investigated. The films with thyme essential oil had higher elongation at break, water vapour permeability and oxygen permeability, lower solubility and tensile strength than control film (p<0.05). The incorporation of thyme essential oil affected transparency values of the films, but only the addition of 1.5% of thyme essential oil significantly reduced the transparency (p<0.05). In the film matrix, molecular organisation and intermolecular interaction were changed by thyme essential oil addition. The films with thyme essential oil had a heterogeneous surface and a relatively smooth cross-section structure. Slightly higher phase transition and lower glass transition temperatures were observed in films with thyme essential oil. The antioxidant capacity of the films was improved by incorporating thyme essential oil depending on its volume fraction.

  19. Antioxidant and chelating capacity of Maillard reaction products in amino acid-sugar model systems: applications for food processing.

    Mondaca-Navarro, Blanca A; Ávila-Villa, Luz A; González-Córdova, Aarón F; López-Cervantes, Jaime; Sánchez-Machado, Dalia I; Campas-Baypoli, Olga N; Rodríguez-Ramírez, Roberto

    2017-08-01

    Maillard reaction products (MRP) have gained increasing interest owing to their both positive and negative effects on human health. Aqueous amino acid-sugar model systems were studied in order to evaluate the antioxidant and chelating activity of MRP under conditions similar to those of food processing. Amino acids (cysteine, glycine, isoleucine and lysine) combined with different sugars (fructose or glucose) were heated to 100 and 130 °C for 30, 60 and 90 min. Antioxidant capacity was evaluated via ABTS and DPPH free radical scavenging assays, in addition to Fe 2+ and Cu 2+ ion chelating capacity. In the ABTS assay, the cysteine-fructose model system presented the highest antioxidant activity at 7.05 µmol mL -1 (130 °C, 60 min), expressed in Trolox equivalents. In the DPPH assay, the cysteine-glucose system presented the highest antioxidant activity at 3.79 µmol mL -1 (100 °C, 90 min). The maximum rate of chelation of Fe 2+ and Cu 2+ was 96.31 and 59.44% respectively in the lysine-fructose and cysteine-glucose systems (100 °C, 30 min). The model systems presented antioxidant and chelating activity under the analyzed temperatures and heating times, which are similar to the processing conditions of some foods. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  20. Storage capacity assessment of liquid fuels production by solar gasification in a packed bed reactor using a dynamic process model

    Kaniyal, Ashok A.; Eyk, Philip J. van; Nathan, Graham J.

    2016-01-01

    of syngas throughput that could be maintained over a full year by 74%, to 5.9 kmol/day. Importantly, a larger heliostat field collection area was calculated to reduce the required storage capacity to approximately halve 35 days, which in absolute terms corresponds to 3.0 tons of syngas. Nevertheless, a requirement for this capacity of storage suggests that the use of the packed bed solar gasification reactor for FT liquids production is unlikely to be viable without substantial changes to the design and operation of the reactor and/or downstream processing plant.

  1. Force production during squats performed with a rotational resistance device under stable versus unstable conditions.

    Moras, Gerard; Vázquez-Guerrero, Jairo

    2015-11-01

    [Purpose] Force production during a squat action on a rotational resistance device (RRD) under stable and unstable conditions. [Subjects and Methods] Twenty-one healthy males were asked to perform six sets of six repetitions of squats on an RRD on either stable or unstable surfaces. The stable and unstable sets were performed on different days. Muscular outputs were obtained from a linear encoder and a strain gauge fixed to a vest. [Results] Overall, the results showed no significant differences for any of the dependent variables across exercise modes. Forcemean outputs were higher in the concentric phase than in the eccentric phase for each condition, but there were no differences in velocity, time or displacement. The forcepeak was similar in the eccentric and concentric phases of movement under both stable and unstable conditions. There were no significant differences in forcemean between sets per condition or between conditions. [Conclusion] These results suggest that performing squats with a RRD achieves similar forcemean and forcepeak under stable and unstable conditions. The forcepeak produced is also similar in concentric and eccentric phases.

  2. Effects of vibration training on force production in female basketball players.

    Fernandez-Rio, Javier; Terrados, Nicolas; Fernandez-Garcia, Benjamin; Suman, Oscar E

    2010-05-01

    The goal of this research project was to investigate the long-term effects of whole-body vibration (WBV) training on force production. Thirty-one female basketball players were randomly distributed in an experimental group: VG (vibration) and a control group: CG (no vibration). Both groups participated in the same training program; however, the experimental group (VG) performed a set of exercises on a vibration platform (Power Plate) at 30- to 35-Hz frequency and 4 mm amplitude, whereas the CG performed the same exercises at 0 Hz. Muscle performance of the legs was tested on a contact-time platform (Ergojump, Finland) through several tests: squat jump (SJ), countermovement jump (CMJ), and 15-second maximal performance jump; squat leg power (knee extension) was also evaluated using an Ergopower machine (Bosco, Italy). After 14 weeks, there was a significant increase (p training has no additive or discernible effect on the strength development of female basketball players after several weeks of use, suggesting that the application of this technology has no advantages over traditional strength training methods.

  3. Influence of wind farm capacity, turbine size and wind speed on production cost: analysis of the actual market trend

    Laali, A.-R.; Meyer, J.-L.

    1996-01-01

    Several studies are undertaken in R and D Division of EDF in collaboration with ERASME association in order to have a good knowledge of the wind energy production costs. These studies are performed in the framework of a wind energy monitoring project and concern the influence of a few parameters like wind farm capacity, turbine size and wind speed on production costs, through an analysis of the actual market trend. Some 50 manufacturers and 140 different kind of wind turbines are considered for this study. The minimum production cost is situated at 800/900 kW wind turbine rated power. This point will probably move to more important powers in the future. This study is valid only for average conditions and some special parameters like particular climate conditions or lack of infrastructure for a special site that could modify the results shown on the curves. The variety of wind turbines (rated power as a function of rotor diameter, height and specific rated power) in the actual market is analysed. A brief analysis of the market trend is also performed. (author)

  4. Transportation Energy Futures Series: Alternative Fuel Infrastructure Expansion: Costs, Resources, Production Capacity, and Retail Availability for Low-Carbon Scenarios

    Melaina, W. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heath, Garvin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sandor, Debra [National Renewable Energy Lab. (NREL), Golden, CO (United States); Steward, Darlene [National Renewable Energy Lab. (NREL), Golden, CO (United States); Vimmerstedt, Laura [National Renewable Energy Lab. (NREL), Golden, CO (United States); Warner, Ethan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Webster, Karen W. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-04-01

    The petroleum-based transportation fuel system is complex and highly developed, in contrast to the nascent low-petroleum, low-carbon alternative fuel system. This report examines how expansion of the low-carbon transportation fuel infrastructure could contribute to deep reductions in petroleum use and greenhouse gas (GHG) emissions across the U.S. transportation sector. Three low-carbon scenarios, each using a different combination of low-carbon fuels, were developed to explore infrastructure expansion trends consistent with a study goal of reducing transportation sector GHG emissions to 80% less than 2005 levels by 2050.These scenarios were compared to a business-as-usual (BAU) scenario and were evaluated with respect to four criteria: fuel cost estimates, resource availability, fuel production capacity expansion, and retail infrastructure expansion.

  5. Reconnaissance investigation of the rough diamond resource potential and production capacity of Côte d’Ivoire

    Chirico, Peter G.; Malpeli, Katherine C.

    2013-01-01

    guéla and a total of 1,100,000 carats remain in Tortiya. Production capacity was calculated for the two study areas for the years 2006–2010 and 2012–2013. Production capacity was found to range from between 38,000 carats and 375,000 carats in Séguéla and from 13,000 carats and 20,000 carats in Tortiya. Further, this study demonstrates that artisanal mining activities can be successfully monitored by using remote sensing and geologic modeling techniques. The production capacity estimates presented here fill a significant data gap and provide policy makers, the UN, and the KP with important information not otherwise available.

  6. Turmoil on the International Oil Markets. Getting Used to Production Capacity Constraints

    Ten Kate, W.; Van Geuns, L.

    2009-01-01

    In 2008 the world experienced a prelude to the new realities of the international oil market. These new realities include a tight balance between supply and demand, the rapidly increased cost of the marginal barrel and the extreme price volatility. This price volatility has driven prices up $50 a barrel in the space of 5 months, only to drop $50 in 2 months after the July 14 peak of $147 a barrel when consumers began to seriously drop out of the market and inventories were drawn down. After the extreme downward correction, the crisis on the international capital markets led to dim expectations about economic growth for the rest of the year and 2009, and this also played a role. However, prices are expected to rebound again, reflecting the fundamental upward shift of oil prices from an average of about $70-80 a barrel to about $110-120 a barrel. This fundamental upward shift is due to a combination of so-called 'underground' and 'above ground' conditions. The 'underground' problems include the size, depth and geological complexities of new oil fields that are driving up the cost per barrel. These complex oil fields need to be taken into production, since 'above ground' problems limit International Oil Companies' (IOCs) ability to access the lower-cost oil in producing countries. The 'above ground' problems slow the pace of development of medium-cost oil in the largest producing countries in the Middle East and Russia. Despite the expectation of a continued demand for oil, oil exporting countries are concerned about the security of demand, and adapt their development plans accordingly. Moreover, with the increased prices of the last few years and the resulting increase in oil revenues, the management of the monetarised oil wealth has become a concern as well. The value of the dollar has been slipping and oil exporting countries tried to match this depreciation by increasing oil prices. China's rise as an important manufacturer in the world, with the accompanying

  7. Black Sea Mixed Layer Sensitivity to Various Wind and Thermal Forcing Products on Climatological Time Scales

    Kara, A. B; Jurlburt, Harley; Wallcraft, Alan; Bourassa, Mark

    2005-01-01

    This study describes atmospheric forcing parameters constructed from different global climatologies, applied to the Black Sea, and investigates the sensitivity of HYbrid Coordinate Ocean Model (HYCOM...

  8. Total water production capacity inversion phenomenon in multi-stage direct contact membrane distillation: A theoretical study

    Lee, Jung Gil

    2017-09-09

    The low thermal efficiency and low water production are among the major challenges that prevent membrane distillation (MD) process from being commercialized. In an effort to design an efficient multi-stage direct contact MD (DCMD) unit through mathematical simulation, a new phenomenon that we refer to as total water production capacity inversion (WPI) has been detected. It is represented by a decrease in the total water production beyond a number of stages or a certain module length. WPI phenomenon, which was confirmed by using two different mathematical models validated experimentally, was found to take place due to the decrease in water vapor flux across the membrane as well as the increase in heat loss by conduction as the membrane length increases. Therefore, WPI should be considered as a critical MD design-criterion, especially for large scale units. Investigations conducted for a simulated multi-stage DCMD process showed that inlet feed and permeate temperatures difference, feed and permeate flow rates, and feed salinity have different effects on WPI. The number of stages (or module length at constant width) that leads to a maximum water production has been determined for different operating parameters. Decreasing inlet feed and permeate temperatures difference, or inlet feed and permeate flow rates and increasing inlet feed temperature at constant temperature difference or inlet feed salinity cause the WPI to take place at lower number of stages. Even though the feed salinity affects negligibly the mean permeate flux, it was clearly shown that it can affect WPI. The results presented herein unveil a hidden phenomenon that is likely to occur during process scale-up procedures and should be considered by process engineers for a proper choice of system design and operating conditions.

  9. Comparison of TOPEX/Poseidon Sea Level and Linear Model Results forced by Various Wind Products for the Tropical Pacific

    Hackert, Eric C.; Busalacchi, Antonio J.

    1997-01-01

    The goal of this paper is to compare TOPEX/Posaidon (T/P) sea level with sea level results from linear ocean model experiments forced by several different wind products for the tropical Pacific. During the period of this study (October 1992 - October 1995), available wind products include satellite winds from the ERS-1 scatterometer product of [HALP 97] and the passive microwave analysis of SSMI winds produced using the variational analysis method (VAM) of [ATLA 91]. In addition, atmospheric GCM winds from the NCEP reanalysis [KALN 96], ECMWF analysis [ECMW94], and the Goddard EOS-1 (GEOS-1) reanalysis experiment [SCHU 93] are available for comparison. The observed ship wind analysis of FSU [STRI 92] is also included in this study. The linear model of [CANE 84] is used as a transfer function to test the quality of each of these wind products for the tropical Pacific. The various wind products are judged by comparing the wind-forced model sea level results against the T/P sea level anomalies. Correlation and RMS difference maps show how well each wind product does in reproducing the T/P sea level signal. These results are summarized in a table showing area average correlations and RMS differences. The large-scale low-frequency temporal signal is reproduced by all of the wind products, However, significant differences exist in both amplitude and phase on regional scales. In general, the model results forced by satellite winds do a better job reproducing the T/P signal (i.e. have a higher average correlation and lower RMS difference) than the results forced by atmospheric model winds.

  10. Multi-objective optimization of surface roughness, cutting forces, productivity and Power consumption when turning of Inconel 718

    Hamid Tebassi

    2016-01-01

    Full Text Available Nickel based super alloys are excellent for several applications and mainly in structural components submitted to high temperatures owing to their high strength to weight ratio, good corrosion resistance and metallurgical stability such as in cases of jet engine and gas turbine components. The current work presents the experimental investigations of the cutting parameters effects (cutting speed, depth of cut and feed rate on the surface roughness, cutting force components, productivity and power consumption during dry conditions in straight turning using coated carbide tool. The mathematical models for output parameters have been developed using Box-Behnken design with 15 runs and Box-Cox transformation was used for improving normality. The results of the analysis have shown that the surface finish was statistically sensitive to the feed rate and cutting speed with the contribution of 43.58% and 23.85% respectively, while depth of cut had the greatest effect on the evolution of cutting force components with the contribution of 79.87% for feed force, 66.92% for radial force and 66.26% for tangential force. Multi-objective optimization procedure allowed minimizing roughness Ra, cutting forces and power consumption and maximizing material removal rate using desirability approach.

  11. Structural Forces and the Production of TB-related Stigma among Haitians in Two Contexts

    Coreil, Jeannine; Mayard, Gladys; Simpson, Kelly M; Lauzardo, Michael; Zhu, Yiliang; Weiss, Mitchell

    2012-01-01

    In recent years renewed interest in health-related stigma has underscored the importance of better understanding the structural underpinnings of stigma processes. This study investigated the influence of sociocultural context on perceived components of tuberculosis-related stigma in non-affected persons by comparing Haitians living in South Florida, USA, with Haitians residing in Léogane Commune, Haiti. Using the methods of cultural epidemiology, a two-phase study based on fieldwork between 2004–07 collected ethnographic data on the cultural context and components of tuberculosis (TB) stigma, and administered a stigma scale developed specifically for these populations. Thematic analysis of stigma components expressed in interviews, focus groups and observation revealed commonalities as well as distinctive emphases of TB stigma in the two comparison groups. Factor analyses of stigma scale scores confirmed the thematic differences revealed in ethnographic findings and highlight the influence of political and economic factors in shaping the meaning and experience of illness. Perceived components of TB stigma among Haitians in South Florida incorporated aspects of Haitian identity as a negatively stereotyped minority community within the larger society, while in Haiti, stigma was associated primarily with poverty, malnutrition, and HIV co-infection. Discussion of findings focuses on the social production of perceived and anticipated stigma as it is influenced by structural forces including the influences of politics, economics, institutional policies, and health service delivery structures. The findings also demonstrate the value of a transnational framework encompassing both sending and receiving countries for understanding TB related stigma in immigrant communities. PMID:20724052

  12. Can Brazil play a more important role in global tuberculosis drug production? An assessment of current capacity and challenges.

    Gemal, Andre; Keravec, Joel; Menezes, Alexandre; Trajman, Anete

    2013-03-27

    Despite the existence of effective treatment, tuberculosis is still a global public health issue. The World Health Organization recommends a six-month four-drug regimen in fixed-dose combination formulation to treat drug sensitive tuberculosis, and long course regimens with several second-line drugs to treat multi-drug resistant tuberculosis. To achieve the projected tuberculosis elimination goal by 2050, it will be essential to ensure a non-interrupted supply of quality-assured tuberculosis drugs. However, quality and affordable tuberculosis drug supply is still a significant challenge for National Tuberculosis Programs. Quality drug production requires a combination of complex steps. The first challenge is to guarantee the quality of tuberculosis active pharmaceutical ingredients, then ensure an adequate manufacturing process, according to international standards, to guarantee final product's safety, efficacy and quality. Good practices for storage, transport, distribution and quality control procedures must follow. In contrast to other high-burden countries, Brazil produces tuberculosis drugs through a strong network of public sector drug manufacturers regulated by a World Health Organization-certified national sanitary authority. The installed capacity for production surpasses the 71,000 needed treatments in the country. However, in order to be prepared to act as a global supplier, important bottlenecks are to be overcome. This article presents an in-depth analysis of the current status of production of tuberculosis drugs in Brazil and the bottlenecks and opportunities for the country to sustain national demand and play a role as a potential global supplier. Raw material and drug production, quality control, international certification and pre-qualification, political commitment and regulatory aspects are discussed, as well recommendations for tackling these bottlenecks. This discussion becomes more important as new drugs and regimens to treat tuberculosis are

  13. Comparative Effects of Different Balance-Training-Progression Styles on Postural Control and Ankle Force Production: A Randomized Controlled Trial.

    Cuğ, Mutlu; Duncan, Ashley; Wikstrom, Erik

    2016-02-01

    Despite the effectiveness of balance training, the exact parameters needed to maximize the benefits of such programs remain unknown. One such factor is how individuals should progress to higher levels of task difficulty within a balance-training program. Yet no investigators have directly compared different balance-training-progression styles. To compare an error-based progression (ie, advance when proficient at a task) with a repetition-based progression (ie, advance after a set amount of repetitions) style during a balance-training program in healthy individuals. Randomized controlled trial. Research laboratory. A total of 28 (16 women, 12 men) physically healthy young adults (age = 21.57 ± 3.95 years, height = 171.60 ± 11.03 cm, weight = 72.96 ± 16.18 kg, body mass index = 24.53 ± 3.7). All participants completed 12 supervised balance-training sessions over 4 weeks. Each session consisted of a combination of dynamic unstable-surface tasks that incorporated a BOSU ball and lasted about 30 minutes. Static balance from an instrumented force plate, dynamic balance as measured via the Star Excursion Balance Test, and ankle force production in all 4 cardinal planes of motion as measured with a handheld dynamometer before and after the intervention. Selected static postural-control outcomes, dynamic postural control, and ankle force production in all planes of motion improved (P .05) for any of the outcome measures. A 4-week balance-training program consisting of dynamic unstable-surface exercises on a BOSU ball improved dynamic postural control and ankle force production in healthy young adults. These results suggest that an error-based balance-training program is comparable with but not superior to a repetition-based balance-training program in improving postural control and ankle force production in healthy young adults.

  14. Assessing photocatalytic power of g-C3N4 for solar fuel production: A first-principles study involving quasi-particle theory and dispersive forces.

    Osorio-Guillén, J M; Espinosa-García, W F; Moyses Araujo, C

    2015-09-07

    First-principles quasi-particle theory has been employed to assess catalytic power of graphitic carbon nitride, g-C3N4, for solar fuel production. A comparative study between g-h-triazine and g-h-heptazine has been carried out taking also into account van der Waals dispersive forces. The band edge potentials have been calculated using a recently developed approach where quasi-particle effects are taken into account through the GW approximation. First, it was found that the description of ground state properties such as cohesive and surface formation energies requires the proper treatment of dispersive interaction. Furthermore, through the analysis of calculated band-edge potentials, it is shown that g-h-triazine has high reductive power reaching the potential to reduce CO2 to formic acid, coplanar g-h-heptazine displays the highest thermodynamics force toward H2O/O2 oxidation reaction, and corrugated g-h-heptazine exhibits a good capacity for both reactions. This rigorous theoretical study shows a route to further improve the catalytic performance of g-C3N4.

  15. Effect of pH buffering capacity and sources of dietary sulfur on rumen fermentation, sulfide production, methane production, sulfate reducing bacteria, and total Archaea in in vitro rumen cultures.

    Wu, Hao; Meng, Qingxiang; Yu, Zhongtang

    2015-06-01

    The effects of three types of dietary sulfur on in vitro fermentation characteristics, sulfide production, methane production, and microbial populations at two different buffer capacities were examined using in vitro rumen cultures. Addition of dry distilled grain with soluble (DDGS) generally decreased total gas production, degradation of dry matter and neutral detergent fiber, and concentration of total volatile fatty acids, while increasing ammonia concentration. High buffering capacity alleviated these adverse effects on fermentation. Increased sulfur content resulted in decreased methane emission, but total Archaea population was not changed significantly. The population of sulfate reducing bacteria was increased in a sulfur type-dependent manner. These results suggest that types of dietary sulfur and buffering capacity can affect rumen fermentation and sulfide production. Diet buffering capacity, and probably alkalinity, may be increased to alleviate some of the adverse effects associated with feeding DDGS at high levels. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Control of cooling processes with forced-air aimed at efficiency energetic and the cooling time of horticultural products

    Silva, Joao Carlos Teles Ribeiro da; Mederos, Barbara Janet Teruel [Universidade Estadual de Campinas (FEAGRI/UNICAMP), SP (Brazil). Fac. de Engenharia Agricola

    2008-07-01

    The application of cooling technologies for the conservation of horticultural products is one of the stages the Cold Chain. In Brazil particularly, as a country with tropical climate with average high temperature almost all year, the application of these technologies is very important because the shelf-life of fresh horticultural products, with quality that the market demands, is directly related to temperature. In particular, the systems of forced air cooling operate according to the flow of air predetermined in the project according to the quantity of product to cool. When actual conditions differ from considerations of the project, as to the quantity of product, a situation very common in agricultural properties and packing houses, the fan will continue providing the nominal flow rate, causing alteration of the cost-benefit relation of process. This project aims at the development of a micro-processing equipment (output current of 4 to 20 mA) to control the rotational speed of the motor of the fan systems, air forced through an inverter of frequency. The objective is development of a Man-Machine Interface, based on an algorithm, which, through the introduction of mass product data and the automatic acquisition of data from temperature of the product and the camera, is calculated the cooling time. The rotation of the engine fan will be amended automatically, to maintain air flow with a proper cost-benefit, in connection with the reduction of cooling time, energy consumption, for the increasing the shelf life of products. (author)

  17. Project Portfolio Management: An Investigation of One Air Force Product Center

    Edmunds, Bryan D

    2005-01-01

    .... This research focuses on the portfolio management (project selection and resource allocation) part of the CTRRP. The purpose of this research effort was to investigate the use of portfolio management within the Air Force...

  18. Black Sea Mixed Layer Sensitivity to Various Wind and Thermal Forcing Products on Climatological Time Scales

    Kara, A. B; Jurlburt, Harley; Wallcraft, Alan; Bourassa, Mark

    2005-01-01

    .... Atmospherically-forced model simulations with no assimilation of any ocean data suggest that the basin-averaged RMS SST differences with respect to the Pathfinder SST climatology can vary from 1.21 degrees C...

  19. Draft environmental impact statement for the siting, construction, and operation of New Production Reactor capacity. Volume 2, Sections 1-6

    1991-04-01

    This (EIS) assesses the potential environmental impacts, both on a broad programmatic level and on a project-specific level, concerning a proposed action to provide new tritium production capacity to meet the nation`s nuclear defense requirements well into the 21st century. A capacity equivalent to that of about a 3,000-megawatt (thermal) heavy-water reactor was assumed as a reference basis for analysis in this EIS; this is the approximate capacity of the existing production reactors at DOE`s Savannah River Site. The EIS programmatic alternatives address Departmental decisions to be made on whether to build new production facilities, whether to build one or more complexes, what size production capacity to provide, and when to provide this capacity. Project-specific impacts for siting, constructing, and operating new production reactor capacity are assessed for three alternative sites: the Hanford Site near Richland, Washington; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; and the Savannah River Site. For each site, the impacts of three reactor technologies (and supporting facilities) are assessed: a heavy-water reactor, a light-water reactor, and a modular high-temperature gas-cooled reactor. Impacts of the no-action alternative also are assessed. The EIS evaluates impacts related to air quality; noise levels; surface water, groundwater, and wetlands; land use; recreation; visual environment; biotic resources; historical, archaeological, and cultural resources; socioeconomics; transportation; waste management; and human health and safety. The EIS describes in detail the potential radioactive releases from new production reactors and support facilities and assesses the potential doses to workers and the general public. This volume contains the analysis of programmatic alternatives, project alternatives, affected environment of alternative sites, environmental consequences, and environmental regulations and permit requirements.

  20. Draft environmental impact statement for the siting, construction, and operation of New Production Reactor capacity. Volume 3, Sections 7-12, Appendices A-C

    1991-04-01

    This Environmental Impact Statement (EIS) assesses the potential environmental impacts, both on a broad programmatic level and on a project-specific level, concerning a proposed action to provide new tritium production capacity to meet the nation`s nuclear defense requirements well into the 21st century. A capacity equivalent to that of about a 3,000-megawatt (thermal) heavy-water reactor was assumed as a reference basis for analysis in this EIS; this is the approximate capacity of the existing production reactors at DOE`s Savannah River Site near Aiken, South Carolina. The EIS programmatic alternatives address Departmental decisions to be made on whether to build new production facilities, whether to build one or more complexes, what size production capacity to provide, and when to provide this capacity. Project-specific impacts for siting, constructing, and operating new production reactor capacity are assessed for three alternative sites: the Hanford Site near Richland, Washington; the Idaho National Engineering Laboratory near Idaho Falls, Idaho; and the Savannah River Site. For each site, the impacts of three reactor technologies (and supporting facilities) are assessed: a heavy-water reactor, a light-water reactor, and a modular high-temperature gas-cooled reactor. Impacts of the no-action alternative also are assessed. The EIS evaluates impacts related to air quality; noise levels; surface water, groundwater, and wetlands; land use; recreation; visual environment; biotic resources; historical, archaeological, and cultural resources; socioeconomics; transportation; waste management; and human health and safety. The EIS describes in detail the potential radioactive releases from new production reactors and support facilities and assesses the potential doses to workers and the general public. This volume contains references; a list of preparers and recipients; acronyms, abbreviations, and units of measure; a glossary; an index and three appendices.

  1. Magnetic properties, acid neutralization capacity, and net acid production of rocks in the Animas River Watershed Silverton, Colorado

    McCafferty, Anne E.; Yager, Douglas B.; Horton, Radley M.; Diehl, Sharon F.

    2006-01-01

    Federal land managers along with local stakeholders in the Upper Animas River watershed near Silverton, Colorado are actively designing and implementing mine waste remediation projects to mitigate the effects of acid mine drainage from several abandoned hard rock metal mines and mills. Local source rocks with high acid neutralization capacity (ANC) within the watershed are of interest to land managers for use in these remediation projects. A suite of representative samples was collected from propylitic to weakly sericitic-altered volcanic and plutonic rocks exposed in outcrops throughout the watershed. Acid-base accounting laboratory methods coupled with mineralogic and geochemical characterization provide insight into lithologies that have a range of ANC and net acid production (NAP). Petrophysical lab determinations of magnetic susceptibility converted to estimates for percent magnetite show correlation with the environmental properties of ANC and NAP for many of the lithologies. A goal of our study is to interpret watershed-scale airborne magnetic data for regional mapping of rocks that have varying degrees of ANC and NAP. Results of our preliminary work are presented here.

  2. Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells.

    Zhu, Jie; Wang, Peng; Yu, Zhimin; Lai, Wei; Cao, Yi; Huang, Pinbo; Xu, Qiaodong; Yu, Menglei; Xu, Junyao; Huang, Zitong; Zeng, Bing

    2016-01-01

    Diabetes mellitus is frequently accompanied by chronic complications like delayed wound healing, which is consider to be attributed to the accumulation of advanced glycosylation end product (AGE). However, the impacts of AGE on epidermal stem cells (ESCs) are largely unknown. This study aims to address the influence and mechanism of AGE on ESCs. ESCs isolated from rats were cultured in AGE-modified bovine serum albumin and transfected with small interfering RNA to knock down AGE-specific receptor (AGER). Expression of stem cell markers integrin β1 (ITGB1) and keratin 19 (KRT19), cell viability, apoptosis and reactive oxygen species (ROS) were examined. Wnt pathway-related factors Wnt family member 1 (WNT1), WNT3A, β-catenin, v-myc avian myelocytomatosis viral oncogene homolog (MYC), cyclin D1 (CCND1) and matrix metallopeptidase 7 (MMP7) were quantified. The interaction between forkhead box O1 (FOXO1) and β-catenin was assessed by co-immunoprecipitation. Results indicated that AGE down-regulated ITGB1 and KRT19 expression, suppressed ESC viability and promoted apoptosis, and ROS level ( P factor 1 to interact with β-catenin, which might help to elucidate the mechanism of AGE repressing ESCs. This study helps to understand the mechanism of accumulated AGE in affecting ESC capacities, and provides potential therapeutic targets to meliorate diabetic wound healing.

  3. Modeling the Effects of Trait Diversity on Short-term Adaptive Capacity and Long-term Productivity of Phytoplankton Communities

    Smith, S. L.; Vallina, S. M.; Merico, A.

    2016-02-01

    We examine Biodiversity and Ecosystem Function (BEF) in a model phytoplankton community, using two recently developed mechanisms for sustaining diversity. The Trait Diffusion (TD) formulation represents the maintenance of diversity via endogenous mechanisms, such as inter-generational trait plasticity and rapid evolution. The 'Kill-the-Winner' (KTW) formulation for grazing sustains prey biodiversity via the exogenous mechanism of active prey switching. We implement both TD and KTW in a continuous trait-distribution model using simplified size-scalings to define a gleaner-opportunist trade-off for a phytoplankton community. By simulating semi-continuous culture experiments with periodic external dilutions, we test the dynamic response of the phytoplankton community to different scenarios of pulsed nutrient supply. We quantify the short-term Adaptive Capacity (AC) of the community by the specific growth rate averaged over the first 3 days of perturbations, and the Long-term Productivity (LP) by its average over the entire 120 day period of perturbations. When either the frequency or intensity of pulses is low, both AC and LP tend to decrease with diversity (and vice versa). Trait diversity has more impact on AC, particularly for pulses of high frequency or intensity, for which it tends to increase gradually at first, then steeply, and then to saturate with increasing diversity. For pulses of moderate intensity and frequency, increasing trait diversity from low to moderate levels leads to a trade-off between enhancing AC while slightly decreasing LP. Ultimately, we find that sustaining diversity increases the speed at which the phytoplankton community changes its composition in terms of size and hence nutrient acquisition traits, which may have implications for the transfer of productivity through the foodweb.

  4. Bilateral deficit in explosive force production is not caused by changes in agonist neural drive.

    Matthew W Buckthorpe

    Full Text Available Bilateral deficit (BLD describes the phenomenon of a reduction in performance during synchronous bilateral (BL movements when compared to the sum of identical unilateral (UL movements. Despite a large body of research investigating BLD of maximal voluntary force (MVF there exist a paucity of research examining the BLD for explosive strength. Therefore, this study investigated the BLD in voluntary and electrically-evoked explosive isometric contractions of the knee extensors and assessed agonist and antagonist neuromuscular activation and measurement artefacts as potential mechanisms. Thirteen healthy untrained males performed a series of maximum and explosive voluntary contractions bilaterally (BL and unilaterally (UL. UL and BL evoked twitch and octet contractions were also elicited. Two separate load cells were used to measure MVF and explosive force at 50, 100 and 150 ms after force onset. Surface EMG amplitude was measured from three superficial agonists and an antagonist. Rate of force development (RFD and EMG were reported over consecutive 50 ms periods (0-50, 50-100 and 100-150 ms. Performance during UL contractions was compared to combined BL performance to measure BLD. Single limb performance during the BL contractions was assessed and potential measurement artefacts, including synchronisation of force onset from the two limbs, controlled for. MVF showed no BLD (P = 0.551, but there was a BLD for explosive force at 100 ms (11.2%, P = 0.007. There was a BLD in RFD 50-100 ms (14.9%, P = 0.004, but not for the other periods. Interestingly, there was a BLD in evoked force measures (6.3-9.0%, P<0.001. There was no difference in agonist or antagonist EMG for any condition (P≥0.233. Measurement artefacts contributed minimally to the observed BLD. The BLD in volitional explosive force found here could not be explained by measurement issues, or agonist and antagonist neuromuscular activation. The BLD in voluntary and evoked explosive force

  5. Capacity and investments in power production. Studies concerning Germany, the Netherlands and Poland; Kapasitet og investeringer i kraftproduksjon. Landstudier for Tyskland, Nederland og Polen

    Haugland, Torleif; Magnus, Eivind; Moen, Paal; Bowitz, Einar

    1998-12-01

    This report describes the production capacity for electricity in Germany, the Netherlands and Poland and presents plans existing in these countries for investments in new capacity and scrapping of existing capacity. Using economic theory it discusses some issues that influence investments in a liberalized market. It is part of a project undertaken to quantify the value of power in the Norwegian hydroelectric power system. The observations and conclusions will form an important empirical foundation for the analysis of the adaptation and stability properties of the Nordic power market as one approaches full capacity with respect to power at peak load. The report will be followed up by an analysis of the developments of investments, market balance and prices up to 2015 in the three countries. These countries have considerable surplus capacities, but for reasons that vary from country to country. The composition of the surplus capacities also vary considerably from one country to the other, which is important for the impact that the capacity and market balance in these countries might have on the Nordic power market in the future. 16 refs., 23 figs., 17 tabs.

  6. THE EFFECTS OF HEIGHT AND DISTANCE ON THE FORCE PRODUCTION AND ACCELERATION IN MARTIAL ARTS STRIKES

    Cynthia A. Bir

    2009-11-01

    Full Text Available Almost all cultures have roots in some sort of self defence system and yet there is relatively little research in this area, outside of a sports related environment. This project investigated different applications of strikes from Kung Fu practitioners that have not been addressed before in the literature. Punch and palm strikes were directly compared from different heights and distances, with the use of a load cell, accelerometers, and high speed video. The data indicated that the arm accelerations of both strikes were similar, although the force and resulting acceleration of the target were significantly greater for the palm strikes. Additionally, the relative height at which the strike was delivered was also investigated. The overall conclusion is that the palm strike is a more effective strike for transferring force to an object. It can also be concluded that an attack to the chest would be ideal for maximizing impact force and moving an opponent off balance

  7. Early interferon-γ production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cells.

    Tonney S Nyirenda

    2010-10-01

    Full Text Available Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible. High case-fatality rates and increasing antibiotic resistance require new approaches to the management of this disease. Impaired cellular immunity caused by defects in the T helper 1 pathway lead to intracellular disease with Salmonella that can be countered by IFNγ administration. This report identifies the lymphocyte subsets that produce IFNγ early in Salmonella infection.Intracellular cytokine staining was used to identify IFNγ production in blood lymphocyte subsets of ten healthy adults with antibodies to Salmonella (as evidence of immunity to Salmonella, in response to stimulation with live and heat-killed preparations of the D23580 invasive African isolate of Salmonella Typhimurium. The absolute number of IFNγ-producing cells in innate, innate-like and adaptive lymphocyte subpopulations was determined.Early IFNγ production was found in the innate/innate-like lymphocyte subsets: γδ-T cells, NK cells and NK-like T cells. Significantly higher percentages of such cells produced IFNγ compared to adaptive αβ-T cells (Student's t test, P<0.001 and ≤0.02 for each innate subset compared, respectively, with CD4(+- and CD8(+-T cells. The absolute numbers of IFNγ-producing cells showed similar differences. The proportion of IFNγ-producing γδ-T cells, but not other lymphocytes, was significantly higher when stimulated with live compared with heat-killed bacteria (P<0.0001.Our findings indicate an inherent capacity of innate/innate-like lymphocyte subsets to produce IFNγ early in the response to Salmonella infection. This may serve to control intracellular infection and reduce the threat of extracellular spread of disease with bacteremia which becomes life-threatening in the absence of protective antibody. These innate cells may also help mitigate against the effect on IFN

  8. Validity of the Myotest® in measuring force and power production in the squat and bench press.

    Comstock, Brett A; Solomon-Hill, Glenn; Flanagan, Shawn D; Earp, Jacob E; Luk, Hui-Ying; Dobbins, Kathryn A; Dunn-Lewis, Courtenay; Fragala, Maren S; Ho, Jen-Yu; Hatfield, Disa L; Vingren, Jakob L; Denegar, Craig R; Volek, Jeff S; Kupchak, Brian R; Maresh, Carl M; Kraemer, William J

    2011-08-01

    The purpose of this study was to verify the concurrent validity of a bar-mounted Myotest® instrument in measuring the force and power production in the squat and bench press exercises when compared to the gold standard of a computerized linear transducer and force platform system. Fifty-four men (bench press: 39-171 kg; squat: 75-221 kg) and 43 women (bench press: 18-80 kg; squat: 30-115 kg) (age range 18-30 years) performed a 1 repetition maximum (1RM) strength test in bench press and squat exercises. Power testing consisted of the jump squat and the bench throw at 30% of each subject's 1RM. During each measurement, both the Myotest® instrument and the Celesco linear transducer of the directly interfaced BMS system (Ballistic Measurement System [BMS] Innervations Inc, Fitness Technology force plate, Skye, South Australia, Australia) were mounted to the weight bar. A strong, positive correlation (r) between the Myotest and BMS systems and a high correlation of determination (R2) was demonstrated for bench throw force (r = 0.95, p bench throw power (r = 0.96, p < 0.05) (R2 = 0.93); squat jump force (r = 0.98, p < 0.05) (R2 = 0.97); and squat jump power (r = 0.91, p < 0.05) (R2 = 0.82). In conclusion, when fixed on the bar in the vertical axis, the Myotest is a valid field instrument for measuring force and power in commonly used exercise movements.

  9. Design, Explanation, and Evaluation of Training Model Structures Based on Learning Organization--In the Cement Industry with a Nominal Production Capacity of Ten Thousand Tons

    Rahimian, Hamid; Kazemi, Mojtaba; Abbspour, Abbas

    2017-01-01

    This research aims to determine the effectiveness of training based on learning organization in the staff of cement industry with production capacity over ten thousand tons. The purpose of this study is to propose a training model based on learning organization. For this purpose, the factors of organizational learning were introduced by…

  10. Influence of renewable sources of energy on the operation of the production capacity in electrical power systems

    Nikolova-Potseva, Sofija

    2012-01-01

    interconnection systems, i.e. wind occurrence during periods of operation of the system near the technical minimum of thermal power plants. The doctoral thesis presents the results from the analyzed occurrence of suppressed energy, when wind power is injected into the system during periods when thermal power plants operate near the technical minimum. Further comparison was made of the possibilities for wind energy injection into the system for different wind power plants installed capacity in the considered system. In PhD dissertation, also, the emission of pollutants from thermal power plants, that used various types of fossil fuels such as: solid, liquid and gaseous, is considered. Then the reduction of CO 2 has been analyzed if wind power plants are integrated in the power system. Therefore the benefits from the production of electrical energy from wind power plants in terms of reducing production costs in the system and reducing the environmental impacts caused by the emission of pollutants in the environment has been investigated. (Author)

  11. Bias Correction of Satellite Precipitation Products (SPPs) using a User-friendly Tool: A Step in Enhancing Technical Capacity

    Rushi, B. R.; Ellenburg, W. L.; Adams, E. C.; Flores, A.; Limaye, A. S.; Valdés-Pineda, R.; Roy, T.; Valdés, J. B.; Mithieu, F.; Omondi, S.

    2017-12-01

    SERVIR, a joint NASA-USAID initiative, works to build capacity in Earth observation technologies in developing countries for improved environmental decision making in the arena of: weather and climate, water and disasters, food security and land use/land cover. SERVIR partners with leading regional organizations in Eastern and Southern Africa, Hindu Kush-Himalaya, Mekong region, and West Africa to achieve its objectives. SERVIR develops hydrological applications to address specific needs articulated by key stakeholders and daily rainfall estimates are a vital input for these applications. Satellite-derived rainfall is subjected to systemic biases which need to be corrected before it can be used for any hydrologic application such as real-time or seasonal forecasting. SERVIR and the SWAAT team at the University of Arizona, have co-developed an open-source and user friendly tool of rainfall bias correction approaches for SPPs. Bias correction tools were developed based on Linear Scaling and Quantile Mapping techniques. A set of SPPs, such as PERSIANN-CCS, TMPA-RT, and CMORPH, are bias corrected using Climate Hazards Group InfraRed Precipitation with Station (CHIRPS) data which incorporates ground based precipitation observations. This bias correction tools also contains a component, which is included to improve monthly mean of CHIRPS using precipitation products of the Global Surface Summary of the Day (GSOD) database developed by the National Climatic Data Center (NCDC). This tool takes input from command-line which makes it user-friendly and applicable in any operating platform without prior programming skills. This presentation will focus on this bias-correction tool for SPPs, including application scenarios.

  12. Effect of slow release-Fampridine on muscle strength, rate of force development, functional capacity and cognitive function in an enriched population of MS patients. A randomized, double blind, placebo controlled study

    Jensen, H B; Nielsen, J L; Ravnborg, M.

    2016-01-01

    contraction (MVC) and rate of force development (RFD) of the lower extremities and 2) to replicate previously published data on the effect of slow release-Fampridine (SR-Fampridine) on the functional capacity of the lower limbs, the upper limb and cognitive function, in persons with multiple sclerosis (pw....... Furthermore, a significant effect of SR-Fampridine on T25FW, SSST and 5-STS was demonstrated. CONCLUSION: Gold standard dynamometry assessment of muscle strength showed improved MVC and RFD in persons with MS treated with SR-Fampridine compared to placebo. Furthermore, previous findings on the effects of SR...

  13. Impact of future climate change on wheat production in relation to plant-available water capacity in a semiaridenvironment

    Yang, Yanmin; Liu, De Li; Anwar, Muhuddin Rajin; Zuo, Heping; Yang, Yonghui

    2014-02-01

    Conceptions encompassing climate change are irreversible rise of atmospheric carbon dioxide (CO2) concentration, increased temperature, and changes in rainfall both in spatial- and temporal-scales worldwide. This will have a major impact on wheat production, particularly if crops are frequently exposed to a sequence, frequency, and intensity of specific weather events like high temperature during growth period. However, the process of wheat response to climate change is complex and compounded by interactions among atmospheric CO2 concentration, climate variables, soil, nutrition, and agronomic management. In this study, we use the Agricultural Production Systems sIMulator (APSIM)-wheat model, driven by statistically downscaled climate projections of 18 global circulation models (GCMs) under the 2007 Intergovernmental Panel on Climate Change (IPCC) Special Report on Emission Scenarios (SRES) A2 CO2 emission scenario to examine impact on future wheat yields across key wheat growing regions considering different soil types in New South Wales (NSW) of Australia. The response of wheat yield, yield components, and phenology vary across sites and soil types, but yield is closely related to plant available water capacity (PAWC). Results show a decreasing yield trend during the period of 2021-2040 compared to the baseline period of 1961-1990. Across different wheat-growing regions in NSW, grain yield difference in the future period (2021-2040) over the baseline (1961-1990) varies from +3.4 to -14.7 %, and in most sites, grain number is decreased, while grain size is increased in future climate. Reduction of wheat yield is mainly due to shorter growth duration, where average flowering and maturing time are advanced by an average of 11 and 12 days, respectively. In general, larger negative impacts of climate change are exhibited in those sites with higher PAWC. Current wheat cultivars with shorter growing season properties are viable in the future climate, but breading for

  14. Comparative Effects of Different Balance-Training–Progression Styles on Postural Control and Ankle Force Production: A Randomized Controlled Trial

    Cuğ, Mutlu; Duncan, Ashley; Wikstrom, Erik

    2016-01-01

    Context:  Despite the effectiveness of balance training, the exact parameters needed to maximize the benefits of such programs remain unknown. One such factor is how individuals should progress to higher levels of task difficulty within a balance-training program. Yet no investigators have directly compared different balance-training–progression styles. Objective:  To compare an error-based progression (ie, advance when proficient at a task) with a repetition-based progression (ie, advance after a set amount of repetitions) style during a balance-training program in healthy individuals. Design:  Randomized controlled trial. Setting:  Research laboratory. Patients or Other Participants:  A total of 28 (16 women, 12 men) physically healthy young adults (age = 21.57 ± 3.95 years, height = 171.60 ± 11.03 cm, weight = 72.96 ± 16.18 kg, body mass index = 24.53 ± 3.7). Intervention(s):  All participants completed 12 supervised balance-training sessions over 4 weeks. Each session consisted of a combination of dynamic unstable-surface tasks that incorporated a BOSU ball and lasted about 30 minutes. Main Outcome Measure(s):  Static balance from an instrumented force plate, dynamic balance as measured via the Star Excursion Balance Test, and ankle force production in all 4 cardinal planes of motion as measured with a handheld dynamometer before and after the intervention. Results:  Selected static postural-control outcomes, dynamic postural control, and ankle force production in all planes of motion improved (P .05) for any of the outcome measures. Conclusions:  A 4-week balance-training program consisting of dynamic unstable-surface exercises on a BOSU ball improved dynamic postural control and ankle force production in healthy young adults. These results suggest that an error-based balance-training program is comparable with but not superior to a repetition-based balance-training program in improving postural control and ankle force production in

  15. The Role of Physical and Physiological Capacities and Their Modification on the Tolerance to Various Stress Experienced by Air Force Personnel

    1984-06-30

    2. To partition the energy utilization during HSG and RTE into oxidation of fat and carbohydrate components; and glycogen utilization and lactate...and physical conditioning. Given the entrance of women into the Air Force Academy and the acknowledged interaction of thermoregulation-dehydration on...basketball, wrestling, soccer and cross-country teams. E-7. CO2 Rebreathing Method The final noninvasive method of assessing cardiac function was the

  16. Chronic clenbuterol treatment compromises force production without directly altering skeletal muscle contractile machinery

    Py, G; Ramonatxo, C; Sirvent, P; Sanchez, A M J; Philippe, A G; Douillard, A; Galbès, O; Lionne, C; Bonnieu, A; Chopard, A; Cazorla, O; Lacampagne, A; Candau, R B

    2015-01-01

    Clenbuterol is a β2-adrenergic receptor agonist known to induce skeletal muscle hypertrophy and a slow-to-fast phenotypic shift. The aim of the present study was to test the effects of chronic clenbuterol treatment on contractile efficiency and explore the underlying mechanisms, i.e. the muscle contractile machinery and calcium-handling ability. Forty-three 6-week-old male Wistar rats were randomly allocated to one of six groups that were treated with either subcutaneous equimolar doses of clenbuterol (4 mg kg−1 day−1) or saline solution for 9, 14 or 21 days. In addition to the muscle hypertrophy, although an 89% increase in absolute maximal tetanic force (Po) was noted, specific maximal tetanic force (sPo) was unchanged or even depressed in the slow twitch muscle of the clenbuterol-treated rats (P muscle contraction and relaxation force kinetics indicated that clenbuterol treatment significantly reduced the rate constant of force development and the slow and fast rate constants of relaxation in extensor digitorum longus muscle (P fast rate constant of relaxation in soleus muscle (P fibres (fast twitch fibres) from clenbuterol-treated animals demonstrated decreased amplitude after 14 days (−19%, P < 0.01) and 21 days (−25%, P < 0.01). In conclusion, we showed that chronic clenbuterol treatment reduces contractile efficiency, with altered contraction and relaxation kinetics, but without directly altering the contractile machinery. Lower Ca2+ release during contraction could partially explain these deleterious effects. PMID:25656230

  17. Lift vs. drag based mechanisms for vertical force production in the smallest flying insects.

    Jones, S K; Laurenza, R; Hedrick, T L; Griffith, B E; Miller, L A

    2015-11-07

    We used computational fluid dynamics to determine whether lift- or drag-based mechanisms generate the most vertical force in the flight of the smallest insects. These insects fly at Re on the order of 4-60 where viscous effects are significant. Detailed quantitative data on the wing kinematics of the smallest insects is not available, and as a result both drag- and lift-based strategies have been suggested as the mechanisms by which these insects stay aloft. We used the immersed boundary method to solve the fully-coupled fluid-structure interaction problem of a flexible wing immersed in a two-dimensional viscous fluid to compare three idealized hovering kinematics: a drag-based stroke in the vertical plane, a lift-based stroke in the horizontal plane, and a hybrid stroke on a tilted plane. Our results suggest that at higher Re, a lift-based strategy produces more vertical force than a drag-based strategy. At the Re pertinent to small insect hovering, however, there is little difference in performance between the two strategies. A drag-based mechanism of flight could produce more vertical force than a lift-based mechanism for insects at Re<5; however, we are unaware of active fliers at this scale. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Origin and radiative forcing of black carbon aerosol: production and consumption perspectives.

    Meng, Jing; Liu, Junfeng; Yi, Kan; Yang, Haozhe; Guan, Dabo; Liu, Zhu; Zhang, Jiachen; Ou, Jiamin; Dorling, Stephen; Mi, Zhifu; Shen, Huizhong; Zhong, Qirui; Tao, Shu

    2018-04-24

    Air pollution, a threat to air quality and human health, has attracted ever-increasing attention in recent years. In addition to having local influence, air pollutants can also travel the globe via atmospheric circulation and international trade. Black carbon (BC), emitted from incomplete combustion, is a unique but representative particulate pollutant. This study tracked down the BC aerosol and its direct radiative forcing to the emission sources and final consumers using the global chemical transport model (MOZART-4), the rapid radiative transfer model for general circulation simulations (RRTM) and a multiregional input-output analysis (MRIO). BC is physically transported (i.e., atmospheric transport) from western to eastern countries in the mid-latitude westerlies, but its magnitude is near an order of magnitude higher if the virtual flow embodied in international trade is considered. The transboundary effects on East and South Asia by other regions increased from about 3% (physical transport only) to 10% when considering both physical and virtual transport. The influence efficiency on East Asia is also large because of the comparatively large emission intensity and emission-intensive exports (e.g., machinery and equipment). The radiative forcing in Africa imposed by consumption from Europe, North America and East Asia (0.01Wm-2) was even larger than the total forcing in North America. Understanding the supply chain and incorporating both atmospheric and virtual transport may improve multilateral cooperation on air pollutant mitigation both domestically and internationally.

  19. What's Happening to American Labor Force and Productivity Measurements? Proceedings of a Conference Sponsored by the National Council on Employment Policy (Washington, D.C., June 17, 1982).

    Upjohn (W.E.) Inst. for Employment Research, Kalamazoo, MI.

    This volume contains four papers presented at a 1982 conference sponsored by the National Council on Employment Policy. It begins with a brief policy statement warning that labor force and productivity data systems face deterioration because of budget cuts that have forced a decline in the quality and quantity of the published information and…

  20. Machinery and labour force requirements for forest chip production in Finland in 2020

    Kaerhae, K.; Strandsroem, M. (Metsaeteho Oy, Helsinki (Finland)), Email: kalle.karha@metsateho.fi, Email: markus.strandstrom@metsateho.fi; Lahtinen, P.; Elo, J. (Poeyry Energy Oy, Espoo (Finland)), Email: perttu.lahtinen@poyry.com, Email: juha.elo@poyry.com

    2009-07-01

    The research carried out by Metsaeteho Oy and Poeyry Energy Oy estimated how much machinery and labour would be needed for large-scale forest chip production if the use of forest chips increases extensively in Finland during the coming decade. If the production and consumption of forest chips are 25 to 30 TWh in Finland 2020, then 1,900 to 2,200 machinery units, i.e. machines and trucks, would be needed. This would mean total investments in production machinery of 530 to 630 million euro (VAT 0 %). The labour demand would be 3,400 to 4,000 machine operators and drivers, and 4,200 to 5,100 labour years including indirect labour. Respectively, if the production and consumption of forest chips is 15 to 20 TWh in Finland in 2020, then the production machinery requirement would be 1,100 to 1,500 machines and trucks. The total machinery investment cost would be 320 to 420 million euro (VAT 0 %) and the calculated labour demand 2,000 to 2,700 machine operators and drivers (2,500 to 3,400 labour years). The results of the study indicated that forest chip production resources will be a major bottleneck in reaching the consumption target of 12 million m3, i.e. around 24 TWh of forest chips in Finland by 2020. (orig.)

  1. Synthesis and granulation of a titanosilicate with adsorption capacity for Cs to be used for treating de ILLW of the Ezeiza Radioisotope Production Plant

    Curi, Rodrigo; Bianchi, Hugo L; Luca, Vittorio

    2012-01-01

    The sitinakite structured titanosilicate is widely used for treating ILLW thanks to its capacity for adsorbing both Cs-137 and Sr-90. Its effectiveness lies in its incredibly high selectivity for such radioisotopes, which makes it useful in complex isotope solutions and even in strong acid and alkaline conditions. In Argentina, an off-the-shelve titanosilicate was used in Ezeiza's radioisotope production plant. Because of commercial restrictions, it is no longer available so an inhouse production is being developed. The aim of this project consists of the following: 1. Synthesis of titanosilicate and structural characterization 2. Adsorption kinetics of Cs + 3. Upscale of the synthesis process 4. Assessment of the influence of synthesis temperature and time on product crystallinity 5. Measurement of adsorption capacity of commercial titanosilicates IE910, IE911 and novel RC15H 6. Separative performance column essay and breakthrough plot 7. Chemical and radiolysis resistance of the adsorbent powder binder Polyacrylonitrile (PAN) in contact with the actual waste Throughout this work we have studied the optimum synthesis conditions capable of rendering a sitinakite structured titanosilicate, assessed its Cs + adsorption kinetics, adsorption capacity, crystal phase and purity via DRX, particle size with Laser Light Scattering technique. We have also conducted column breakthrough experiments and tried the chemical and radiolysis resistance of the final product (author)

  2. Development of capacity for measuring ionizing radiation in aircraft crew

    Federico, C.A.; Goncalez, O.L.

    2011-01-01

    This paper describes the activities performed in a research program of the Institute of Advanced Studies, Brazil, belonging to the Brazilian Air Force, joining to researches from Brazilian Nuclear Energy Commission, in order to bring to Brazil the capacity and acknowledge necessary to the evaluation of dose from ionizing radiation originated in the cosmic radiation and its by products which fall on aircraft crews

  3. Forewings match the formation of leading-edge vortices and dominate aerodynamic force production in revolving insect wings.

    Chen, Di; Kolomenskiy, Dmitry; Nakata, Toshiyuki; Liu, Hao

    2017-10-20

    In many flying insects, forewings and hindwings are coupled mechanically to achieve flapping flight synchronously while being driven by action of the forewings. How the forewings and hindwings as well as their morphologies contribute to aerodynamic force production and flight control remains unclear yet. Here we demonstrate that the forewings can produce most of the aerodynamic forces even with the hindwings removed through a computational fluid dynamic study of three revolving insect wing models, which are identical to the wing morphologies and Reynolds numbers of hawkmoth (Manduca sexta), bumblebee (Bombus ignitus) and fruitfly (Drosophila melanogaster). We find that the forewing morphologies match the formation of leading-edge vortices (LEV) and are responsible for generating sufficient lift forces at the mean angles of attack and the Reynolds numbers where the three representative insects fly. The LEV formation and pressure loading keep almost unchanged with the hindwing removed, and even lead to some improvement in power factor and aerodynamic efficiency. Moreover, our results indicate that the size and strength of the LEVs can be well quantified with introduction of a conical LEV angle, which varies remarkably with angles of attack and Reynolds numbers but within the forewing region while showing less sensitivity to the wing morphologies. This implies that the forewing morphology very likely plays a dominant role in achieving low-Reynolds number aerodynamic performance in natural flyers as well as in revolving and/or flapping micro air vehicles. © 2017 IOP Publishing Ltd.

  4. Neural control of muscle force: indications from a simulation model

    Luca, Carlo J. De

    2013-01-01

    We developed a model to investigate the influence of the muscle force twitch on the simulated firing behavior of motoneurons and muscle force production during voluntary isometric contractions. The input consists of an excitatory signal common to all the motor units in the pool of a muscle, consistent with the “common drive” property. Motor units respond with a hierarchically structured firing behavior wherein at any time and force, firing rates are inversely proportional to recruitment threshold, as described by the “onion skin” property. Time- and force-dependent changes in muscle force production are introduced by varying the motor unit force twitches as a function of time or by varying the number of active motor units. A force feedback adjusts the input excitation, maintaining the simulated force at a target level. The simulations replicate motor unit behavior characteristics similar to those reported in previous empirical studies of sustained contractions: 1) the initial decrease and subsequent increase of firing rates, 2) the derecruitment and recruitment of motor units throughout sustained contractions, and 3) the continual increase in the force fluctuation caused by the progressive recruitment of larger motor units. The model cautions the use of motor unit behavior at recruitment and derecruitment without consideration of changes in the muscle force generation capacity. It describes an alternative mechanism for the reserve capacity of motor units to generate extraordinary force. It supports the hypothesis that the control of motoneurons remains invariant during force-varying and sustained isometric contractions. PMID:23236008

  5. Dressed dibaryon production as a new mechanism for basic nuclear force and meson-exchange currents

    Kukulin, V.I.

    2003-01-01

    A novel concept for the nuclear force is introduced. The approach assumes that a specific dressed six-quark state (dressed dibaryon) is generated in NN collision at intermediate and short ranges. The new dressing mechanism providing π-, σ-, ρ- and ω-meson clouds around the six quark core is discussed. These novel components produce both strong intermediate-range attraction and short-range repulsion in the NN sector due to the s-channel exchange mechanism which is supplemented with conventional π- and 2π- Yukawa exchanges at intermediate and long ranges. The model developed is demonstrated to lead to numerous new effects and contributions in many fields of nuclear physics. (author)

  6. Does an Exercise Intervention Improving Aerobic Capacity Among Construction Workers Also Improve Musculoskeletal Pain, Work Ability, Productivity, Perceived Physical Exertion, and Sick Leave?

    Gram, Bibi; Holtermann, Andreas; Bültmann, Ute

    2012-01-01

    OBJECTIVE:: To investigate whether an exercise intervention shown to increase aerobic capacity, would also lead to less musculoskeletal pain; improved work ability, productivity, and perceived physical exertion; and less sick leave. METHODS:: Sixty-seven construction workers were randomized...... into an exercise group training 3 × 20 minutes per week and a control group. Questionnaires and text messages were completed before and after the 12-week intervention. RESULTS:: No significant changes were found in musculoskeletal pain, work ability, productivity, perceived physical exertion, and sick leave...... with the intervention. Questionnaires and text messages provided similar results of pain and work ability. CONCLUSIONS:: Although the intervention improved aerobic capacity, it was not successful in improving musculoskeletal pain and other work-related factors. A detectable improvement presumably requires a more...

  7. Capacity Building in Southern Africa: Experiences and Reflections--Towards Joint Knowledge Production and Social Change in International Development Cooperation

    Zeelen, Jacques; van der Linden, Josje

    2009-01-01

    The intent of capacity building in international development cooperation is to enable people to control their own development. Important premises are ownership, choice and self-esteem. The authors analyse the dynamics of the enabling process in practice, based on their own experiences working for several years in universities in developing…

  8. The Supply of Medical Radioisotopes. Medical Isotope Supply in the Future: Production Capacity and Demand. Forecast for the 99Mo/99mTc Market, 2015-2020

    Peykov, Pavel; Cameron, Ron

    2014-04-01

    This document presents a forecast of 99 Mo/ 99m Tc production capacity and demand in 2015-2020, when two major irradiators - the OSIRIS and NRU reactors in France and Canada - are expected to exit the global supply chain and new alternative technology projects may be commissioned. The forecast does not attempt to predict shortages, but identify periods when there is an increased risk of disrupted supply, to inform policy makers and other stakeholders. (authors)

  9. Physical forcing of biological productivity in the northern Arabian Sea during the northeast monsoon

    PrasannaKumar, S.; Ramaiah, N.; Gauns, M.; Sarma, V.V.S.S.; Muraleedharan, P.M.; Raghukumar, S.; DileepKumar, M.; Madhupratap, M.

    that this interannual variation is of basin-wide spatial scale. After the termination of winter cooling and subsequent warming during the Spring Intermonsoon, the Arabian Sea has low primary production. During the latter period, micro-organisms, i.e. heterotrophic...

  10. Forest Products Laboratory : supporting the nation's armed forces with valuable wood research for 90 years

    Christopher D. Risbrudt; Robert J. Ross; Julie J. Blankenburg; Charles A. Nelson

    2007-01-01

    Founded in 1910 by the U.S. Forest Service to serve as a centralized, national wood research laboratory, the USDA Forest Products Laboratory (FPL) has a long history of providing technical services to other government agencies, including those within the Defense (DoD). A recent search of FPL’s library and correspondence files revealed that approximately 10,000...

  11. Influence of Anti-TNF and Disease Modifying Antirheumatic Drugs Therapy on Pulmonary Forced Vital Capacity Associated to Ankylosing Spondylitis: A 2-Year Follow-Up Observational Study

    Alberto Daniel Rocha-Muñoz

    2015-01-01

    Full Text Available Objective. To evaluate the effect of anti-TNF agents plus synthetic disease modifying antirheumatic drugs (DMARDs versus DMARDs alone for ankylosing spondylitis (AS with reduced pulmonary function vital capacity (FVC%. Methods. In an observational study, we included AS who had FVC% <80% at baseline. Twenty patients were taking DMARDs and 16 received anti-TNF + DMARDs. Outcome measures: changes in FVC%, BASDAI, BASFI, 6-minute walk test (6MWT, Borg scale after 6MWT, and St. George’s Respiratory Questionnaire at 24 months. Results. Both DMARDs and anti-TNF + DMARDs groups had similar baseline values in FVC%. Significant improvement was achieved with anti-TNF + DMARDs in FVC%, at 24 months, when compared to DMARDs alone (P=0.04. Similarly, patients in anti-TNF + DMARDs group had greater improvement in BASDAI, BASFI, Borg scale, and 6MWT when compared to DMARDs alone. After 2 years of follow-up, 14/16 (87.5% in the anti-TNF + DMARDs group achieved the primary outcome: FVC% ≥80%, compared with 11/20 (55% in the DMARDs group (P=0.04. Conclusions. Patients with anti-TNF + DMARDs had a greater improvement in FVC% and cardiopulmonary scales at 24 months compared with DMARDs. This preliminary study supports the fact that anti-TNF agents may offer additional benefits compared to DMARDs in patients with AS who have reduced FVC%.

  12. Effects of Constant and Doublet Frequency Electrical Stimulation Patterns on Force Production of Knee Extensor Muscles.

    Carole Cometti

    Full Text Available This study compared knee extensors' neuromuscular fatigue in response to two 30-minute stimulation patterns: constant frequency train (CFT and doublet frequency train (DFT. Fifteen men underwent two separate sessions corresponding to each pattern. Measurements included torque evoked by each contraction and maximal voluntary contractions (MVC measured before and immediately after the stimulation sessions. In addition, activation level and torque evoked during doublets (Pd and tetanic contractions at 80-Hz (P80 and 20-Hz (P20 were determined in six subjects. Results indicated greater mean torque during the DFT stimulation session as compared with CFT. But, no difference was obtained between the two stimulation patterns for MVC and evoked torque decreases. Measurements conducted in the subgroup depicted a significant reduction of Pd, P20 and P80. Statistical analyses also revealed bigger P20 immediate reductions after CFT than after DFT. We concluded that DFT could be a useful stimulation pattern to produce and maintain greater force with quite similar fatigue than CFT.

  13. Increased productivity in construction of civil and mining tunnels through the use of high-capacity tunnel-boring machines and continuous belt conveyor muck haulage

    Beatty, J.G.; Ganey, R.J.; Killingsworth, J.E. [Perini Corp., Chicago, IL (United States). US Heavy Division

    1994-12-31

    The use of a large diameter high production tunnel boring machine interfaced with a high capacity continuous belt conveyor system provides a highly productive and cost effective construction system for both civil and mining tunnels. Continuous advance of the tunnel boring machine for a distance of 1,000 feet (305 m) allows for very efficient operation of the system. The available cost reductions will likely prove that this approach to waste handling will make marginally viable projects economically feasible. 9 refs., 10 figs., 1 tab.

  14. Decadal Variations in Eastern Canada's Taiga Wood Biomass Production Forced by Ocean-Atmosphere Interactions.

    Boucher, Etienne; Nicault, Antoine; Arseneault, Dominique; Bégin, Yves; Karami, Mehdi Pasha

    2017-05-26

    Across Eastern Canada (EC), taiga forests represent an important carbon reservoir, but the extent to which climate variability affects this ecosystem over decades remains uncertain. Here, we analyze an extensive network of black spruce (Picea mariana Mill.) ring width and wood density measurements and provide new evidence that wood biomass production is influenced by large-scale, internal ocean-atmosphere processes. We show that while black spruce wood biomass production is primarily governed by growing season temperatures, the Atlantic ocean conveys heat from the subtropics and influences the decadal persistence in taiga forests productivity. Indeed, we argue that 20-30 years periodicities in Sea Surface Temperatures (SSTs) as part of the the Atlantic Multi-decadal Oscillation (AMO) directly influence heat transfers to adjacent lands. Winter atmospheric conditions associated with the North Atlantic Oscillation (NAO) might also impact EC's taiga forests, albeit indirectly, through its effect on SSTs and sea ice conditions in surrounding seas. Our work emphasizes that taiga forests would benefit from the combined effects of a warmer atmosphere and stronger ocean-to-land heat transfers, whereas a weakening of these transfers could cancel out, for decades or longer, the positive effects of climate change on Eastern Canada's largest ecosystem.

  15. Snow driven Radiative Forcing in High Latitude Areas of Disturbance Using Higher Resolution Albedo Products from Landsat and Sentinel-2

    Erb, A.; Li, Z.; Schaaf, C.; Wang, Z.; Rogers, B. M.

    2017-12-01

    Land surface albedo plays an important role in the surface energy budget and radiative forcing by determining the proportion of absorbed incoming solar radiation available to drive photosynthesis and surface heating. In Arctic regions, albedo is particularly sensitive to land cover and land use change (LCLUC) and modeling efforts have shown it to be the primary driver of effective radiative forcing from the biogeophysical effects of LCLUC. In boreal forests, the effects of these changes are complicated during snow covered periods when newly exposed, highly reflective snow can serve as the primary driver of radiative forcing. In Arctic biomes disturbance scars from fire, pest and harvest can remain in the landscape for long periods of time. As such, understanding the magnitude and persistence of these disturbances, especially in the shoulder seasons, is critical. The Landsat and Sentinel-2 Albedo Products couple 30m and 20m surface reflectances with concurrent 500m BRDF Products from the MODerate resolution Imaging Spectroradiometer (MODIS). The 12 bit radiometric fidelity of Sentinel-2 and Landsat-8 allow for the inclusion of high-quality, unsaturated albedo calculations over snow covered surfaces at scales more compatible with fragmented landscapes. Recent work on the early spring albedo of fire scars has illustrated significant post-fire spatial heterogeneity of burn severity at the landscape scale and highlights the need for a finer spatial resolution albedo record. The increased temporal resolution provided by multiple satellite instruments also allows for a better understanding of albedo dynamics during the dynamic shoulder seasons and in historically difficult high latitude locations where persistent cloud cover limits high quality retrievals. Here we present how changes in the early spring albedo of recent boreal forest disturbance in Alaska and central Canada affects landscape-scale radiative forcing. We take advantage of the long historical Landsat record

  16. Comparative Quantitative Assessments of Salivary Ion Activity Product for Hydroxyapatite and Buffering Capacity in Children with Different Caries Experience.

    Anand, Siddharth; Masih, Updesh; Yeluri, Ramakrishna

    If a relation exists between salivary I PHA , buffer capacity and caries experience, then this relationship could be used as screening chair side test for caries risk assessment. One hundred ninety seven children aged 4 to 6 years were examined. Data was collected by interview and clinical examination. They were divided into low, moderate and high caries experience group of 20 children each. Two ml of each sample was used to measure the pH value with pH meter. Regarding the buffering capacity, freshly prepared hydrochloric acid (HCl) was titrated into saliva and pH was recorded. The collected saliva samples were sent to Laboratory for measurement of calcium and phosphorus. I PHA was calculated and the negative logarithms of I PHA were used to determine the enamel solubility. The correlation between salivary I PHA , buffering capacity and caries experience were evaluated. There was a significant relation between pH, log I PHA and dental caries experience, it could be considered as a predictor of dental caries. pH measurement after HCl titration in saliva could be used as chair side screening test for the assessment of caries risk.

  17. Prospects for OPEC capacity

    Adelman, M.A.

    1995-01-01

    OPEC capacity is not exogenous, but responds to demand. Price increases have not been caused by capacity shortages. OPEC nations find it hard to set aside even very small portions of their revenues for oil investment, despite its extreme profitability. Foreign investors face high risks. Production sharing makes their after-tax return even more unstable. (author)

  18. Human resources in primary health care: investments and the driving force of production.

    Maeda, Sayuri Tanaka; Moleiro, Priscilla Francescucci; Egry, Emiko Yoshikawa; Ciosak, Suely Itsuko

    2011-12-01

    The present study describes the composition, the qualification, the salary investment, the workforce produce, and discusses users' accessibility in terms of time at Basic Health Units (BHUs). The study was performed at two BHUs from January to December 2008, and developed by analyzing administrative documents. In both, the composition of professionals according to education level revealed: 21% with a university degree, 27% with a secondary education, and50% with a primary education; showing a positive salary variation. The medical and nursing conducts were the majority at both. The production indicators confirmed: 25 and 37 min/person/month for accessibility, respectively for BHU A and B; R$ 8.43 and R$ 12.11/person/month for the salary investment at both BHUs, and 0.07 appointments/person/month at both BHUs. The professionals' available time is scarce compared to the potential of the demand. The production indicated an opportunity of care < 1 per person/month at a reduced cost.

  19. Characterization of lipids and antioxidant capacity of novel nutraceutical egg products developed with omega-3-rich oils.

    Kassis, Nissan M; Gigliotti, Joseph C; Beamer, Sarah K; Tou, Janet C; Jaczynski, Jacek

    2012-01-15

    Cardiovascular disease has had an unquestioned status of the number one cause of death in the US since 1921. Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) have cardio-protective benefits. However, egg is typically a poor source of ω-3 PUFAs and, in general, the American diet is low in these cardio-protective fatty acids. Novel, nutritionally enhanced egg products were developed by substituting yolk with ω-3 PUFA-rich flaxseed, menhaden, algae, or krill oil. Experimental egg products matched composition of hen egg (whole egg). The experimental egg products, mixed whole egg, and a liquid egg product (Egg Beaters) were microwave-cooked and compared. Although fat, protein, and moisture contents of experimental egg products matched (P > 0.05) mixed whole egg, experimental egg products had more (P egg. Triglycerides were the main lipid class in all experimental egg products except those developed with krill oil, which had even more phospholipids than mixed whole egg. Analysis of thiobarbituric acid reactive substances showed that lipid oxidation of experimental egg products was lower (P 0.05) to mixed whole egg, except for experimental egg products with krill oil. However, peroxide value showed that all egg samples had minimal oxidation. Experimental egg products developed with menhaden or flaxseed oil had the highest (P egg samples. However, experimental egg products with krill oil likely contained a natural antioxidant, astaxanthin. This study demonstrated an alternative approach to developing novel, nutraceutical egg products. Instead of dietary modification of chicken feed, yolk substitution with ω-3 PUFAs oils resulted in enhancement of ω-3 PUFAs beyond levels possible to achieve by modifying chicken feed. Copyright © 2011 Society of Chemical Industry.

  20. Owl-inspired leading-edge serrations play a crucial role in aerodynamic force production and sound suppression.

    Rao, Chen; Ikeda, Teruaki; Nakata, Toshiyuki; Liu, Hao

    2017-07-04

    Owls are widely known for silent flight, achieving remarkably low noise gliding and flapping flights owing to their unique wing morphologies, which are normally characterized by leading-edge serrations, trailing-edge fringes and velvet-like surfaces. How these morphological features affect aerodynamic force production and sound suppression or noise reduction, however, is still not well known. Here we address an integrated study of owl-inspired single feather wing models with and without leading-edge serrations by combining large-eddy simulations (LES) with particle-image velocimetry (PIV) and force measurements in a low-speed wind tunnel. With velocity and pressure spectra analysis, we demonstrate that leading-edge serrations can passively control the laminar-turbulent transition over the upper wing surface, i.e. the suction surface at all angles of attack (0°    15° where owl wings often reach in flight. Our results indicate that the owl-inspired leading-edge serrations may be a useful device for aero-acoustic control in biomimetic rotor designs for wind turbines, aircrafts, multi-rotor drones as well as other fluid machinery.

  1. Development of a new biofertilizer with a high capacity for N2 fixation, phosphate and potassium solubilization and auxin production.

    Leaungvutiviroj, Chaveevan; Ruangphisarn, Pimtida; Hansanimitkul, Pikul; Shinkawa, Hidenori; Sasaki, Ken

    2010-01-01

    Biofertilizers that possess a high capacity for N(2) fixation (Azotobacter tropicalis), and consist of phosphate solubilizing bacteria (Burkhoderia unamae), and potassium solubilizing bacteria (Bacillus subtilis) and produce auxin (KJB9/2 strain), have a high potential for growth and yield enhancement of corn and vegetables (Chinese kale). For vegetables, the addition of biofertilizer alone enhanced growth 4 times. Moreover, an enhancement of growth by 7 times was observed due to the addition of rock phosphate and K-feldspar, natural mineral fertilizers, in combination with the biofertilizer.

  2. The Role of Knowledge Acquisition in Facilitating Customer Involvement in Product Development: Examining the Mediation Effect of Absorptive Capacity

    Dahiyat, Samer E.; Al-Zu'bi, Zu'bi M. F.

    2012-01-01

    Knowledge management has often been linked to product development, innovation, and customisation. In particular, effective exploitation of customer knowledge, through engaging customers in a process of co-creation of products, exemplifies such a link. Accordingly, this research aims to identify those dimensions of knowledge management activities…

  3. European transition to a low carbon electricity system using a mix of variable renewable energies: carbon saving trajectories as functions of production and storage capacity.

    Francois, Baptiste; Creutin, Jean-Dominique

    2016-04-01

    Today, most of the produced energy is generated from fossil energy sources (i.e. coal, petroleum). As a result, the energy sector is still the main source of greenhouse gas in the atmosphere. For limiting greenhouse gas emission, a transition from fossil to renewable energy is required, increasing gradually the fraction energy coming from variable renewable energy (i.e. solar power, wind power and run-of-the river hydropower, hereafter denoted as VRE). VRE penetration, i.e. the percentage of demand satisfied by variable renewables assuming no storage capacity, is hampered by their variable and un-controllable features. Many studies show that combining different VRE over space smoothes their variability and increases their global penetration by a better match of demand fluctuations. When the demand is not fully supplied by the VRE generation, backup generation is required from stored energy (mostly from dams) or fossil sources, the latter being associated with high greenhouse gas emission. Thus the VRE penetration is a direct indicator of carbon savings and basically depends on the VRE installed capacity, its mix features, and on the installed storage capacity. In this study we analyze the European transition to a low carbon electricity system. Over a selection of representative regions we analyze carbon saving trajectories as functions of VRE production and storage capacities for different scenarios mixing one to three VRE with non-renewables. We show substantial differences between trajectories when the mix of sources is far from the local optimums, when the storage capacity evolves. We bring new elements of reflection about the effect of transport grid features from local independent systems to a European "copper plate". This work is part of the FP7 project COMPLEX (Knowledge based climate mitigation systems for a low carbon economy; Project FP7-ENV-2012 number: 308601; http://www.complex.ac.uk/).

  4. Comparison of different tests used in mapping the Greek virgin olive oil production for the determination of its total antioxidant capacity

    Minioti, K. S.; Georgiou, C. A.

    2010-07-01

    This study aims to map the total antioxidant capacity (Tac) of 50 Greek olive oil samples from the 2005-2006 season according to production region and cultivar and to compare the 2, 2'-amino-bis (3-ethylbenzo-thiazoline-6- sulfonic acid (Abets), 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH) and F olin-Ciocalteu tests for use with olive oil. Antioxidant capacities determined in the hydrophilic fraction range between 5.42 - 22.5 mM gallic acid Kg{sup -}1 olive oil for the ABTS method and 1.29 - 9.95 mM Kg{sup -}1 for the DPPH method while in total, olive oil TAC ranges between 77 - 177 mM Kg{sup -}1 as assessed by the DPPH method. The results of total phenol content range between 3.8 and 29.4 mM Kg{sup -}1 olive oil. Total phenol content correlates with total antioxidant capacity assessed in the hydrophilic fraction through the DPPH (r = 0.89) and the ABTS (r = 0.69) assays. The hydrophilic fraction DPPH values correlate significantly with the ABTS values (r = 0.81). However, the DPPH values for total olive oil correlate poorly with the ABTS assay, the Folin-Ciocalteu method and the DPPH assay in hydrophilic fraction. Although total phenolic content shows good correlation with ABTS and DPPH values and could serve as a useful indicator for olive oil antioxidant capacity, the use of a battery of tests contributes to better characterization of the antioxidant capacity of olive oil. (Author) 14 refs.

  5. Evaluation of a handling system for ley crop used in biogas production. Capacities and costs for a centralised system

    Vaagstroem, Lena

    2005-07-01

    Within the Vaextkraft project in Vaesteraas, Sweden, biogas is to be produced out of ley crop and organic waste. The aim of this study has been to estimate the capacities within the handling system used for the ley crop harvest, and the resources needed. For this purpose a model in the form of a calculation program in Excel was built. The model makes it possible to vary parameters such as transport system design, distance from fields to storage, dry matter content and yield. The results showed that it is essential to match the capacities between chopper and transport to minimise the time and cost connected to the harvest. To avoid creating costly bottlenecks in the Vaextkraft case the transport system has to consist of at least two trucks with trailers. The estimates made with the model suggests that the distance to storage is strongly linked to the dimensioning of the transport system, whereas the number of fields and their size has a lesser impact on harvest time and cost. Variation of the dry matter yield from a base scenario had an impact on the cost for harvesting, but not on the choice of transport system. The model couldn't detect any reliable differences in total costs due to the variation of dry matter content between 25-45%. The choice of chopping machinery in the Vaextkraft project leads to small timeliness costs. Together with a reasonable choice of transport system they will only constitute a few percent of the total costs for harvesting.

  6. Ensuring full-capacity production in case of liquid loading in gas wells; Aufrechterhalten der Produktion aus verwaessernden Erdgasbohrungen

    Reinicke, K.M. [Technische Univ. Clausthal (Germany). Inst. fuer Erdoel- und Erdgastechnik; Albrecht, I. [Schlumberger Holding GmbH, Hannover (Germany); Thurow, M. [ILF Consulting Engineers, Muenchen (Germany)

    2007-09-13

    In the late production stages, water production from natural gas wells may become a problem that may require abandoning the well, thus losing valuable productive assets. In a joint project of organisations of the Deutsche Wissenschaftliche Gesellschaft fuer Erdoel, Erdgas und Kohle, a status report was made in 2005, and best practice methods for dewatering natural gas wells were identified. This contribution presents some of the results: common methods for improved liquid unloading from natural gas wells, preconditions for their application, experience of the industries in this field, elements of the selection and planning process, and an outlook. (orig.)

  7. Self-Healing Capacity of Asphalt Mixtures Including By-Products Both as Aggregates and Heating Inductors.

    Vila-Cortavitarte, Marta; Jato-Espino, Daniel; Castro-Fresno, Daniel; Calzada-Pérez, Miguel Á

    2018-05-15

    Major advances have been achieved in the field of self-healing by magnetic induction in which the addition of metallic particles into asphalt mixtures enables repairing their own cracks. This technology has already been proven to increase the life expectancy of roads. Nevertheless, its higher costs in comparison with conventional maintenance caused by the price of virgin metallic particles still makes it unattractive for investment. This research aimed at making this process economically accessible as well as environmentally efficient. To this end, an intense search for suitable industrial by-products to substitute both the virgin metal particles and the natural aggregates forming asphalt mixtures was conducted. The set of by-products used included sand blasting wastes, stainless shot wastes, and polished wastes as metallic particles and other inert by-products as aggregates. The results demonstrated that the by-products were adequately heated, which leads to satisfactory healing ratios in comparison with the reference mixture.

  8. Hydrogen production through small capacity water electrolysis systems; Production d'hydrogene par electrolyse de l'eau. Application a des systemes de petite capacite

    Schulz, Ph. [TotalFinaElf, la Defense 6, 92 - Courbevoie (France)

    2002-01-01

    Less than 1 % of the world's hydrogen is produced by electrolysis of water, in large plants mainly in connection with hydropower. For users requiring extremely pure hydrogen, electrolysis can be a convenient mean of obtaining the required hydrogen quality, where cheap electricity is available. This paper aims at presenting the latest technical developments of small capacity electrolyzers, that could fuel hydrogen cells or internal combustion engines. (author)

  9. Expansion of Production Capacity in the Company Moje podjetje d.o.o. and its Impact on the Organizational Climate in the Company

    Idriz Selimović

    2016-05-01

    Full Text Available Research Question (RQ: In a case study we will discuss the impact of expansion of production at the organizational climate of the company Mojepodjetje d.o.o. Method: When writing of the study was to systematically review the accomplishments of Experts on the surveyed area. We used the employee survey on the topic of expansion of production capacity of the company Mojepodjetjed.o.o. where we reasonably composite questionnaire come up with interesting findings. Results:: As a result of the research presented results of the survey on the planned expansion of production capacities Organization: Organizations must consider the fact that employees are people with feelings, specific desires and aspirations that motivate and inhibit different things. Employees are not just numbers and folders in the Human Resources department, but one of the main drivers of development organizations. With thisstudy we will draw attention to this fact. Originality: In the literature we have not found a similar case example. Our study may encourage critical evaluation of the impact of the human factor in the success of the expansion of operations of the organization. Limitations/Future Research: The study was limited to only one organization in the future it would be good to do a similar study had similar to what the company and to compare the results obtained with our own.

  10. Production of electricity through biomass gasification system downdraft and generator group with a capacity of 50 kVA

    Fabrízio Luiz Figueiredo

    2012-11-01

    Full Text Available This paper presents the results of tests performed with an internal combustion engine adapted to MWM Otto cycle, coupled to an electricity generator with a capacity of 50 kVA, fed exclusively with synthesis gas from a biomass gasifier downdraft, using wood eucalyptus. Also featured are the characteristics and efficiency of the generator set, in order to assess the feasibility of applying the system in remote locations, where biomass is available and the system of conventional electric power transmission is hampered by distance. The synthesis gas generated showed the average composition of 16,9% H2, 20% CO, 10,9% CO2, CH4, 2% and 50,1% N2. The performance of the span was monitored by applying loads of 0, 7, 13, 20,1 and 26,4 kW, the generator, keeping the average voltage of 222 V and currents of 0, 18,5, 33, 51, 84 and 67 A.

  11. Flight mechanics and control of escape manoeuvres in hummingbirds. II. Aerodynamic force production, flight control and performance limitations.

    Cheng, Bo; Tobalske, Bret W; Powers, Donald R; Hedrick, Tyson L; Wang, Yi; Wethington, Susan M; Chiu, George T-C; Deng, Xinyan

    2016-11-15

    The superior manoeuvrability of hummingbirds emerges from complex interactions of specialized neural and physiological processes with the unique flight dynamics of flapping wings. Escape manoeuvring is an ecologically relevant, natural behaviour of hummingbirds, from which we can gain understanding into the functional limits of vertebrate locomotor capacity. Here, we extend our kinematic analysis of escape manoeuvres from a companion paper to assess two potential limiting factors of the manoeuvring performance of hummingbirds: (1) muscle mechanical power output and (2) delays in the neural sensing and control system. We focused on the magnificent hummingbird (Eugenes fulgens, 7.8 g) and the black-chinned hummingbird (Archilochus alexandri, 3.1 g), which represent large and small species, respectively. We first estimated the aerodynamic forces, moments and the mechanical power of escape manoeuvres using measured wing kinematics. Comparing active-manoeuvring and passive-damping aerodynamic moments, we found that pitch dynamics were lightly damped and dominated by the effect of inertia, while roll dynamics were highly damped. To achieve observed closed-loop performance, pitch manoeuvres required faster sensorimotor transduction, as hummingbirds can only tolerate half the delay allowed in roll manoeuvres. Accordingly, our results suggested that pitch control may require a more sophisticated control strategy, such as those based on prediction. For the magnificent hummingbird, we estimated that escape manoeuvres required muscle mass-specific power 4.5 times that during hovering. Therefore, in addition to the limitation imposed by sensorimotor delays, muscle power could also limit the performance of escape manoeuvres. © 2016. Published by The Company of Biologists Ltd.

  12. Comparative Analysis of the Antioxidant Capacities and Phenolic Compounds of Oat and Buckwheat Vinegars During Production Processes.

    Yu, Xiao; Yang, Mei; Dong, Jilin; Shen, Ruiling

    2018-03-01

    This study aimed to explore the dynamic changes in the antioxidant activities and phenolic acid profiles of oat and buckwheat vinegars during different production stages. The results showed that both oat and buckwheat vinegar products comparably attenuated D-galactose-induced oxidative damage in mice serum and liver, indicating no obvious dose dependence within the tested concentrations. However, oat vinegar product revealed more favorable in vitro antioxidant activities than those in buckwheat vinegar product as evaluated by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging abilities. Moreover, the alcoholic fermentation, acetic acid fermentation and fumigating induced successive increase in DPPH radical scavenging abilities and phenolic acid contents of the fermentation substrates of oat and buckwheat vinegars. Importantly, the different fermentation processes of oat and buckwheat vinegars were accompanied by the dynamic migration and transformation of specific phenolic acids across bound, esterified and free fractions. Thus, the antioxidant activities of oat and buckwheat vinegars could be improved through targeted modulation of the generation of specific phenolic acid fractions during production processes. We had evaluated the in vitro and in vivo antioxidant activities and phenolic acid contents of oat and buckwheat vinegars, and further explored the dynamic changes of bound, esterified and free phenolic acid fractions during successive fermentation processes of oat and buckwheat vinegars. This study provided the theoretical guidance for obtaining minor grain vinegar with the optimal antioxidant activities through targeted modulation of fermentation processes. © 2018 Institute of Food Technologists®.

  13. Station Capacity

    Landex, Alex

    2011-01-01

    the probability of conflicts and the minimum headway times into account. The last method analyzes how optimal platform tracks are used by examining the arrival and departure pattern of the trains. The developed methods can either be used separately to analyze specific characteristics of the capacity of a station......Stations are often limiting the capacity of railway networks. This is due to extra need of tracks when trains stand still, trains turning around, and conflicting train routes. Although stations are often the capacity bottlenecks, most capacity analysis methods focus on open line capacity. Therefore...... for platform tracks and the probability that arriving trains will not get a platform track immediately at arrival. The third method is a scalable method that analyzes the conflicts in the switch zone(s). In its simplest stage, the method just analyzes the track layout while the more advanced stages also take...

  14. OPEC future capacity expansions

    Sandrea, I.

    2005-01-01

    This conference presentation examined OPEC future capacity expansions including highlights from 2000-2004 from the supply perspective and actions by OPEC; OPEC spare capacity in 2005/2006; medium-term capacity expansion and investments; long-term scenarios, challenges and opportunities; and upstream policies in member countries. Highlights from the supply perspective included worst than expected non-OPEC supply response; non-OPEC supply affected by a number of accidents and strikes; geopolitical tensions; and higher than expected demand for OPEC crude. OPEC's actions included closer relationship with other producers and consumers; capacity expansions in 2004 and 2005/2006; and OPEC kept the market well supplied with crude in 2004. The presentation also provided data using graphical charts on OPEC net capacity additions until 2005/2006; OPEC production versus spare capacity from 2003 to 2005; OPEC production and capacity to 2010; and change in required OPEC production from 2005-2020. Medium term expansion to 2010 includes over 60 projects. Medium-term risks such as project execution, financing, costs, demand, reserves, depletion, integration of Iraq, and geopolitical tensions were also discussed. The presentation concluded that in the long term, large uncertainties remain; the peak of world supply is not imminent; and continued and enhanced cooperation is essential to market stability. tabs., figs

  15. The effect of coracoacromial ligament excision and acromioplasty on the amount of rotator cuff force production necessary to restore intact glenohumeral biomechanics.

    Budoff, Jeffrey E; Lin, Cheng-Li; Hong, Chih-Kai; Chiang, Florence L; Su, Wei-Ren

    2016-06-01

    Coracoacromial ligament (CAL) excision and acromioplasty increase superior and anterosuperior glenohumeral translation. It is unknown how much of an increase in rotator cuff force production is required to re-establish intact glenohumeral biomechanics after these surgical procedures. We hypothesized that, after CAL excision and acromioplasty, an increase in rotator cuff force production would not be necessary to reproduce the anterosuperior and superior translations of the intact specimens. Nine cadaveric shoulders were subjected to loading in the superior and anterosuperior directions in the intact state after CAL excision, acromioplasty, and recording of the translations. The rotator cuff force was then increased to normalize glenohumeral biomechanics. After CAL excision at 150 and 200 N of loading, an increase in the rotator cuff force by 25% decreased anterosuperior translation to the point where there was no significant difference from the intact specimen's translation. After acromioplasty (and CAL excision) at 150 and 200 N, an increase in the rotator cuff force of 25% and 30%, respectively, decreased superior translation to the point where there was no significant difference from the intact specimen's translation. At 150 to 200 N of loading, CAL excision and acromioplasty increase the rotator cuff force required to maintain normal glenohumeral biomechanics by 25% to 30%. After a subacromial decompression, the rotator cuff has an increased force production requirement to maintain baseline glenohumeral mechanics. Under many circumstances, in vivo force requirements may be even greater after surgical attenuation of the coracoacromial arch. Basic Science Study; Biomechanics. Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  16. Environmentally friendly and highly productive bi-component melt spinning of thermoregulated smart polymer fibres with high latent heat capacity

    Ch. Cherif

    2018-03-01

    Full Text Available A stable and reproducible bi-component melt spinning process on an industrial scale incorporating Phase Change Material (PCM into textile fibres has been successfully developed and carried out using a melt spinning machine. The key factor for a successful bi-component melt spinning process is that a deep insight into the thermal and rheological behaviour of PCM using Difference Scanning Calorimetry (DSC, Thermogravimetric Analysis (TGA, and an oscillatory rheological investigation. PCM is very sensitive to the temperature and residence time of the melt spinning process. It is found that the optimal process temperature of PCM is 210 °C. The textile-physical properties and the morphology of the melt spun and further drawn bi-component core and sheath fibres (bico fibres were investigated and interpreted. The heat capacities of PCM incorporated in bico fibres were also determined by means of DSC. The melt spun bico fibres integrating PCM provide a high latent heat of up to 22 J/g, which is three times higher than that of state-of-the-art fibres, which were also obtained using the melt spinning process. Therefore, they have the potential to be used as smart polymer fibres for textile and other technical applications.

  17. The Supply of Medical Radioisotopes. 2016 Medical Isotope Supply Review: 99Mo/99mTc Market Demand and Production Capacity Projection 2016-2021

    Charlton, Kevin; )

    2016-03-01

    Medical diagnostic imaging techniques using technetium-99m ( 99 mTc) account for approximately 80% of all nuclear medicine procedures, representing 30-40 million examinations Worldwide every year. Disruptions in the supply chain of these medical isotopes - which have half-lives of 66 hours for molybdenum-99 ( 99 Mo) and only 6 hours for 99m Tc, and thus must be produced continuously - can lead to cancellations or delays in important medical testing services. Supply reliability has been challenged over the past decade due to unexpected shutdowns and extended refurbishment periods at some of the 99 Mo-producing research reactors and processing facilities. These shutdowns have at times created conditions for extended global supply shortages (e.g. 2009-2010). At the request of its member countries, the Nuclear Energy Agency (NEA) became involved in global efforts to ensure a secure supply of 99 Mo/ 99m Tc. Since June 2009, the NEA and its High-level Group on the Security of Supply of Medical Radioisotopes (HLG-MR) have examined the causes of supply shortages and developed a policy approach, including principles and supporting recommendations to address those causes. The NEA has also reviewed the global 99 Mo supply situation periodically, to highlight periods of potential reduced supply and to underscore the case for implementing the HLG-MR policy approach in a timely and globally consistent manner. In 2012, the NEA released a 99 Mo supply and demand forecast up to 2030, identifying periods of potential low supply relative to demand. That 2012 forecast was updated with a report in 2014 that focused on the much shorter 2015-2020 period. That report was updated in 2015 with a report, '2015 Medical Isotope Supply Review: 99 Mo/ 99m Tc Market Demand and Production Capacity Projection 2015-2020' (NEA, 2015), which focused on the same period. This report updates the 2015 report, and focuses on the important 2016-2021 period. At the end of 2015, the OSIRIS reactor

  18. The Supply of Medical Radioisotopes. 2015 Medical Isotope Supply Review: 99Mo/99mTc Market Demand and Production Capacity Projection 2015-2020

    Charlton, Kevin; )

    2015-08-01

    Medical diagnostic imaging techniques using technetium-99m ( 99m Tc) account for approximately 80% of all nuclear medicine procedures, representing 30-40 million examinations Worldwide every year. Disruptions in the supply chain of these medical isotopes - which have half-lives of 66 hours for molybdenum-99 ( 99 Mo) and only 6 hours for 99m Tc, and thus must be produced continuously - can lead to cancellations or delays in important medical testing services. Unfortunately, supply reliability has been challenged over the past decade due to unexpected shutdowns and extended refurbishment periods at some of the mostly ageing, 99 Mo-producing research reactors and processing facilities. These shutdowns have at times created conditions for extended global supply shortages (e.g. 2009-2010). At the request of its member countries, the Nuclear Energy Agency (NEA) became involved in global efforts to ensure a secure supply of 99 Mo/ 99m Tc. Since June 2009, the NEA and its High-level Group on the Security of Supply of Medical Radioisotopes (HLG-MR) have examined the causes of supply shortages and developed a policy approach, including principles and supporting recommendations to address those causes. The NEA has also reviewed the global 99 Mo supply situation periodically, using the most up-to-date data available from supply chain participants, to highlight periods of potential reduced supply and to underscore the case for implementing the HLG-MR policy approach in a timely and globally consistent manner. In 2012, the NEA released a M o supply and demand forecast up to 2030, identifying periods of potential low supply relative to demand. That 2012 forecast was updated with a report 'Medical Isotope Supply in the Future: Production Capacity and Demand Forecast for the 99 Mo/ 99m Tc Market 2015-2020' (NEA, 2014) in 2014 that focused on the much shorter 2015-2020 period. This report updates the 2014 report, and continues to focus on the potentially critical 2015

  19. Capacity of biochar application to maintain energy crop productivity: soil chemistry, sorghum growth, and runoff water quality effects.

    Schnell, Ronnie W; Vietor, Donald M; Provin, Tony L; Munster, Clyde L; Capareda, Sergio

    2012-01-01

    Pyrolysis of crop biomass generates a by-product, biochar, which can be recycled to sustain nutrient and organic C concentrations in biomass production fields. We evaluated effects of biochar rate and application method on soil properties, nutrient balance, biomass production, and water quality. Three replications of eight sorghum [ (L.) Moench] treatments were installed in box lysimeters under greenhouse conditions. Treatments comprised increasing rates (0, 1.5, and 3.0 Mg ha) of topdressed or incorporated biochar supplemented with N fertilizer or N, P, and K fertilizer. Simulated rain was applied at 21 and 34 d after planting, and mass runoff loss of N, P, and K was measured. A mass balance of total N, P, and K was performed after 45 d. Returning 3.0 Mg ha of biochar did not affect sorghum biomass, soil total, or Mehlich-3-extractable nutrients compared to control soil. Yet, biochar contributed to increased concentration of dissolved reactive phosphorus (DRP) and mass loss of total phosphorus (TP) in simulated runoff, especially if topdressed. It was estimated that up to 20% of TP in topdressed biochar was lost in surface runoff after two rain events. Poor recovery of nutrients during pyrolysis and excessive runoff loss of nutrients for topdressed biochar, especially K, resulted in negative nutrient balances. Efforts to conserve nutrients during pyrolysis and incorporation of biochar at rates derived from annual biomass yields will be necessary for biochar use in sustainable energy crop production. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  20. The greenhouse gas intensity and potential biofuel production capacity of maize stover harvest in the US Midwest

    Jones, Curtis D. [Department of Geographical Sciences, University of Maryland, College Park MD 20742 USA; Zhang, Xuesong [Joint Global Change Research Institute, Pacific Northwest National Laboratory and University of Maryland, College Park MD 20740 USA; Reddy, Ashwan D. [Department of Geographical Sciences, University of Maryland, College Park MD 20742 USA; Robertson, G. Philip [Great Lakes Bioenergy Research Center, Michigan State University, East Lansing MI 48824 USA; W.K. Kellogg Biological Station, Michigan State University, Hickory Corners MI 49060 USA; Department of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing MI 48824 USA; Izaurralde, Roberto César [Department of Geographical Sciences, University of Maryland, College Park MD 20742 USA; Texas A& M AgriLife Research & Extension Center, Temple TX 76502 USA

    2017-08-11

    Agricultural residues are important sources of feedstock for a cellulosic biofuels industry that is being developed to reduce greenhouse gas emissions and improve energy independence. While the US Midwest has been recognized as key to providing maize stover for meeting near-term cellulosic biofuel production goals, there is uncertainty that such feedstocks can produce biofuels that meet federal cellulosic standards. Here, we conducted extensive site-level calibration of the Environmental Policy Integrated Climate (EPIC) terrestrial ecosystems model and applied the model at high spatial resolution across the US Midwest to improve estimates of the maximum production potential and greenhouse gas emissions expected from continuous maize residue-derived biofuels. A comparison of methodologies for calculating the soil carbon impacts of residue harvesting demonstrates the large impact of study duration, depth of soil considered, and inclusion of litter carbon in soil carbon change calculations on the estimated greenhouse gas intensity of maize stover-derived biofuels. Using the most representative methodology for assessing long-term residue harvesting impacts, we estimate that only 5.3 billion liters per year (bly) of ethanol, or 8.7% of the near-term US cellulosic biofuel demand, could be met under common no-till farming practices. However, appreciably more feedstock becomes available at modestly higher emissions levels, with potential for 89.0 bly of ethanol production meeting US advanced biofuel standards. Adjustments to management practices, such as adding cover crops to no-till management, will be required to produce sufficient quantities of residue meeting the greenhouse gas emission reduction standard for cellulosic biofuels. Considering the rapid increase in residue availability with modest relaxations in GHG reduction level, it is expected that management practices with modest benefits to soil carbon would allow considerable expansion of potential cellulosic

  1. Capacitated dynamic lot sizing with capacity acquisition

    Li, Hongyan; Meissner, Joern

    2011-01-01

    One of the fundamental problems in operations management is determining the optimal investment in capacity. Capacity investment consumes resources and the decision, once made, is often irreversible. Moreover, the available capacity level affects the action space for production and inventory...

  2. Jobs and the resource curse in the sun: The effects of oil production on female labor force participation in California counties from 1980-2010

    Zavala, Gabriel

    This study aims to evaluate the relationship between oil income and the female labor force participation rate in California for the years of 1980, 1990, 2000 and 2010 using panel linear regression models. This study also aims to visualize the spatial patterns of both variables in California through Hot Spot analysis at the county level for the same years. The regression found no sign of a relationship between oil income and female labor force participation rate but did find evidence of a positive relationship between two income control variables and the female labor force participation rate. The hot spot analysis also found that female labor force participation cold spots are not spatially correlated with oil production hot spots. These findings contribute new methodologies at a finer scale to the very nuanced discussion of the resource curse in the United States.

  3. Orbital forcing on marine organic and carbonate production in the Indo-Pacific during the last 1.7 Myrs

    Beaufort, L.; Bolton, C. T.; Mazur, J. C.; Gally, Y.

    2017-12-01

    The Western Pacific Warm Pool (WPWP) is a place of intense energy storage and redistribution … It is climatically relatively stable with, for example, little seasonality in sea surface temperature (SST). However, significant changes occur in the vertical structure of the upper ocean related to El Nino Southern Oscillation dynamics. These changes significantly impact the phytoplankton communities that are adapted to specific conditions in different layers of the photic zone, and are precisely recorded in the sediments by microfossils such as those produced by coccolithophores. Core MD97-2540 was retrieved on the Eauripik rise in the WPWP and covers, in 37 metres, a time interval spanning the last 1.7 million years (Myrs). Two samples were prepared (settling slide) every 5 cm. The entire coccolith assemblage was counted and identified automatically in each sample using the software SYRACO. Morphometric characteristics (length, thickness, mass…) were measured on every coccolith. Primary productivity (PP) was estimated using a transfer function based on the percentage of the species Florisphaera profunda. Changes in mass (M) of the dominant coccolithophore group, the Noelarhabdaceae (including Emilianiaand Gephyrocapsa), were studied. We also estimated the coccolithophore carbonate export production (CCEP). Those 3 parameters (PP, M and CCEP) show a significant imprint of precession and eccentricity of the Earth's orbit. In contrast to SST and planktic foraminiferal oxygen isotopes measured on the same samples, the coccolithophore parameters exhibit significant 400 kyr cyclicity, and the 100 kyr cycle is present prior to its appearance in the SST and oxygen isotope records 0.9 Myrs ago. This indicates direct forcing by insolation and seasonality on the WPWP, independent of global climatic variations. A discussion of the relationship between the Indian Monsoon and ENSO on orbital and longer timescales is enabled via comparisons with PP and CCEP measured at a similar

  4. Modeling the oxidative capacity of the atmosphere of the south coast air basin of California. 2. HOx radical production.

    Griffin, Robert J

    2004-02-01

    The production of HOx radicals in the South Coast Air Basin of California is investigated during the smog episode of September 9, 1993 using the California Institute of Technology (CIT) air-quality model. Sources of HOx(hydroxyl, hydroperoxy, and organic peroxy radicals) incorporated into the associated gas-phase chemical mechanism include the combination of excited-state singlet oxygen (formed from ozone (O3) photolysis (hv)) with water, the photolysis of nitrous acid, hydrogen peroxide (H2O2), and carbonyl compounds (formaldehyde (HCHO) or higher aldehydes and ketones), the consumption of aldehydes and alkenes (ALK) by the nitrate radical, and the consumption of alkenes by O3 and the oxygen atom (O). At a given time or location for surface cells and vertical averages, each route of HOx formation may be the greatest contributor to overall formation except HCHO-hv, H2O2-hv, and ALK-O, the latter two of which are insignificant pathways in general. The contribution of the ALK-O3 pathway is dependent on the stoichiometric yield of OH, but this pathway, at least for the studied smog episode, may not be as generally significant as previous research suggests. Future emissions scenarios yield lower total HOx production rates and a shift in the relative importance of individual pathways.

  5. A human hemi-cornea model for eye irritation testing: quality control of production, reliability and predictive capacity.

    Engelke, M; Zorn-Kruppa, M; Gabel, D; Reisinger, K; Rusche, B; Mewes, K R

    2013-02-01

    We have developed a 3-dimensional human hemi-cornea which comprises an immortalized epithelial cell line and keratocytes embedded in a collagen stroma. In the present study, we have used MTT reduction of the whole tissue to clarify whether the production of this complex 3-D-model is transferable into other laboratories and whether these tissues can be constructed reproducibly. Our results demonstrate the reproducible production of the hemi-cornea model according to standard operation procedures using 15 independent batches of reconstructed hemi-cornea models in two independent laboratories each. Furthermore, the hemi-cornea tissues have been treated with 20 chemicals of different eye-irritating potential under blind conditions to assess the performance and limitations of our test system comparing three different prediction models. The most suitable prediction model revealed an overall in vitro-in vivo concordance of 80% and 70% in the participating laboratories, respectively, and an inter-laboratory concordance of 80%. Sensitivity of the test was 77% and specificity was between 57% and 86% to discriminate classified from non-classified chemicals. We conclude that additional physiologically relevant endpoints in both epithelium and stroma have to be developed for the reliable prediction of all GHS classes of eye irritation in one stand alone test system. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Transportation Energy Futures Series: Alternative Fuel Infrastructure Expansion: Costs, Resources, Production Capacity, and Retail Availability for Low-Carbon Scenarios

    Melaina, M. W.; Heath, G.; Sandor, D.; Steward, D.; Vimmerstedt, L.; Warner, E.; Webster, K. W.

    2013-04-01

    Achieving the Department of Energy target of an 80% reduction in greenhouse gas emissions by 2050 depends on transportation-related strategies combining technology innovation, market adoption, and changes in consumer behavior. This study examines expanding low-carbon transportation fuel infrastructure to achieve deep GHG emissions reductions, with an emphasis on fuel production facilities and retail components serving light-duty vehicles. Three distinct low-carbon fuel supply scenarios are examined: Portfolio: Successful deployment of a range of advanced vehicle and fuel technologies; Combustion: Market dominance by hybridized internal combustion engine vehicles fueled by advanced biofuels and natural gas; Electrification: Market dominance by electric drive vehicles in the LDV sector, including battery electric, plug-in hybrid, and fuel cell vehicles, that are fueled by low-carbon electricity and hydrogen. A range of possible low-carbon fuel demand outcomes are explored in terms of the scale and scope of infrastructure expansion requirements and evaluated based on fuel costs, energy resource utilization, fuel production infrastructure expansion, and retail infrastructure expansion for LDVs. This is one of a series of reports produced as a result of the Transportation Energy Futures (TEF) project, a Department of Energy-sponsored multi-agency project initiated to pinpoint underexplored transportation-related strategies for abating GHGs and reducing petroleum dependence.

  7. The mechanisms underlying corrosion product formation and deposition in nuclear power plant circuits through the action of galvanic and thermal electromotive forces

    Brusakov, V.P.; Sedov, V.M.; Khitrov, Yu.A.; Brusov, K.N.; Razmashkin, N.V.; Versin, V.V.; Rybalchenko, I.L.

    1983-01-01

    From a theoretical standpoint, the processes of formation of corrosion products in nuclear power plant circuits, deposition of corrosion products on the circuit surfaces, formation of an equilibrium concentration of corrosion products in the coolant, and distribution of radionuclides resulting from corrosion in different parts of the circuit are considered. It is shown that the main driving forces for the mass-transfer processes in the circuits are the thermal and galvanic electromotive forces (EMF) of the microcouples. On the basis of the theoretical concepts developed the authors have obtained analytical dependences for calculating the individual stages of the process of corrosion product transfer in the circuits. The mechanisms underlying the processes which occur as a result of thermal and galvanic EMFs are considered, together with the factors influencing these processes. The results of verification of the dependences by computational methods are given and they are compared with operational data from nuclear and conventional thermal power plants and with experimental data. (author)

  8. Critical force during tethered swimming for the evaluation of aerobic capacity and prediction of performances in freestyle swimming DOI:10.5007/1980-0037.2010v12n1p14

    Marcelo Papoti

    2010-12-01

    Full Text Available The present study investigated the relationship of critical force (Fcrit with lactate threshold (LLNA and the intensity corresponding to VO2max (iVO2max in tethered swimming (TS, and their correlation with maximal performance in 400-m (V400 and 30-min (VT30 freestyle swimming (FS. Seven swimmers were submitted to a TS incremental test for the determination of LLNA and iVO2max. For the determination of Fcrit, the swimmers performed four exercises to exhaustion at intensities (F corresponding to 87%, 104%, 118% and 134% of iVO2max for the calculation of time limits (Tlim. Fcrit corresponded to the linear coefficient of the ratio between F and 1/tlim. The maximal performance in FS corresponded to the mean velocity obtained during maximal exercise of 400-m and 30-min crawl swimming. Fcrit (51.97 ± 4.02 N was significantly lower than iVO2max (60.21 ± 8.73 N but not than LLNA (45.89 ± 8.73. Fcrit was significantly correlated with iVO2max (0.97, LLNA (0.88, V400 (0.85, and VT30 (0.86. These data suggest that Fcrit can be used for the determination of aerobic capacity, prescription of a TS training program, and prediction of performance in FS.

  9. First production of larvae using cryopreserved sperm: Effects of preservation temperature and cryopreservation on European eel sperm fertilization capacity

    Asturiano, J.F.; Sørensen, Sune Riis; Perez, L.

    2016-01-01

    Sperm cryopreservation is a useful tool in captive fish reproduction management, that is to synchronize gamete production, especially in the case of species as the European eel, where the time of female spawning readiness is unpredictable. Several protocols to cryopreserve sperm of this species....... Fertilization of two egg batches was attempted. Diluted sperm caused a similar percentage of fertilized eggs and a similar number of embryos and larvae, independently of storage temperature (4 or 20°C). The cryopreserved sperm resulted in a lower percentage of fertilized eggs, but embryos developed and a few...... larvae ('cryolarvae') were obtained 55 h after fertilization in one of the two egg batches. This result evidences that the tested cryopreservation protocol is applicable for eel reproduction management, although improvements will be required to enhance fertilization success...

  10. Production capacity as a remedy for profit generator A capacidade de produção como recurso gerador de ganhos

    Norberto Tamborlin

    2013-03-01

    Full Text Available The gradual growth of the flexography market generates different expectations in organizations of this segment. To ensure the fulfillment of the demand and ensure its market share, it is important to know the real productive capacity of its plant. The research aimed to identify the capacity of the sector recording a stereotype workshop the city of Blumenau/SC. Was defined as qualitative research, objective descriptive and as in the investigation, the research is characterized as action research. Data were collected from the daily monitoring of the processes performed in the recording industry, observing the development of activities, recording information in reports and informal interviews with employees. Thus, the data were triangulated and presented in tables and figures. The results of this investigation was identified the bottleneck of production as well as the existence of hours shutdowns for lack of service, and made ​​suggestions to optimize production capacity, as well as strategies to increase earnings.O crescimento gradativo do mercado de flexografia gera diversas expectativas nas organizações deste segmento. Para garantir o atendimento da demanda e garantir a sua fatia de mercado, é importante conhecer a real capacidade produtiva da sua unidade de produção. A pesquisa teve como objetivo identificar a capacidade de produção do setor de gravação de uma clicheria da cidade de Blumenau/SC. Foi definida como pesquisa qualitativa, de objetivo descritivo e quanto aos procedimentos de investigação, a pesquisa se caracterizou como pesquisa-ação. Os dados foram coletados a partir do acompanhamento diário dos processos realizados no setor de gravação, observação do desenvolvimento das atividades, registro das informações em relatórios e entrevistas informais com os funcionários. Dessa forma, os dados obtidos foram triangulados e apresentados em figuras e tabelas. Como resultados desta investigação, foi identificado o

  11. EFFECT OF COMMERCIALIZATION ON PRODUCTIVE CAPACITY AMONG CASSAVA PRODUCING HOUSEHOLDS IN IKWUANO LOCAL GOVERNMENT AREA OF ABIA STATE, NIGERIA

    Ogbonnaya Ukeh OTEH

    2014-10-01

    Full Text Available The study investigated factors affecting commercialization of cassava producing household in Ikwuano Local Government Area, Abia State, Nigeria. It specifically examined the socio-economic characteristics of cassava household; determine commercialization index and analyzed factors that influence commercialization among cassava producing households. The study employed purposive sampling technique in the selection of 120 respondents from one local government area (LGA based on characteristics of interest, nearness and other related features. The selection was done from 6 communities at the rate of 20 respondents per community. Analytically, descriptive statistics, household commercialization index (HCI, and multiple regression analysis were used. The results showed that the mean age of the cassava producing household was about 40 years with a mean farming experience of 14 years. They are mostly married with an average of 5 persons per households. The result further revealed that only a few households (less than 2% have very high commercialization orientation, which exposes the level of farming in the area. With respect to determinants of factors that influence commercialization, value of output, farm size, sex, nearness to market, membership of cooperative and farming experience were significant and found to exhibit varying degree. The study therefore recommends that support policies that sustain and improve the productivity among farming household especially land tenure policy issues, greater incentives policies for farmers in the rural areas; linkages between farm households and the markets; increase access and exchange of information on markets.

  12. Gender differences in power production, energetic capacity and efficiency of elite cross‑country skiers during whole‑body, upper‑body, and arm poling.

    Hegge, Ann Magdalen; Bucher, Elias; Ettema, Gertjan; Faude, Oliver; Holmberg, Hans-Christer; Sandbakk, Øyvind

    2016-02-01

    To characterize gender differences in power output, energetic capacity and exercise efficiency during whole-body (WP), upper-body (UP), and arm poling (AP). Ten male and ten female elite cross-country skiers, matched for international performance level, completed three incremental submaximal tests and a 3-min self-paced performance test on a Concept2 SkiErg. Power output, cardiorespiratory and kinematic variables were monitored. Body composition was determined by dual-energy X-ray absorptiometry. The men demonstrated 87, 97 and 103% higher power output, and 51, 65 and 71% higher VO2peak (L min(−1)) than the women during WP, UP and AP, respectively, while utilizing ~10% more of their running VO2max in all modes (all P lean mass in the whole body, upper body and arms (all P production and peak aerobic capacity increased sequentially from WP to UP to AP, coinciding with a greater portion of the muscle mass in the arms of the men. Although the men and women employed each poling technique differently, the estimated efficiency of double poling was independent of gender.

  13. Ellagic acid derivatives, ellagitannins, proanthocyanidins and other phenolics, vitamin C and antioxidant capacity of two powder products from camu-camu fruit (Myrciaria dubia).

    Fracassetti, Daniela; Costa, Carlos; Moulay, Leila; Tomás-Barberán, Francisco A

    2013-08-15

    The aims of this study were the evaluation of polyphenols and vitamin C content, and antioxidant capacity of dehydrated pulp powder and the dried flour obtained from the skin and seeds residue remaining after pulp preparation from camu-camu (Myrciaria dudia). Fifty-three different phenolics were characterised by HPLC-DAD-ESI-MS-MS and UPLC-HR-QTOF-MS-MS. The phenolic content of camu-camu flour was higher than that of the pulp powder (4007.95 mg/100 g vs. 48.54 mg/100 g). In both products the flavonol myricetin and conjugates, ellagic acid and conjugates and ellagitannins were detected. Cyanidin 3-glucoside, and quercetin and its glycosides were only found in the pulp powder, while proanthocyanidins were only present in the flour (3.5 g/100 g, mean degree of polymerisation 3). The vitamin C content was lower in pulp powder (3.5%) than in the flour (9.1%). The radical-scavenging capacity of both powders was determined by the DPPH, ABTS and ORAC assays, and was higher for camu-camu flour as could be expected for its higher phenolics and vitamin C content. Comparative analyses with fresh camu-camu berries indicate that some transformations occur during processing. Analysis of fresh berries showed that ellagic acid derivatives and ellagitannins were mainly present in the seeds, while proanthocyanidins were present both in the seeds and skin. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Comparison of bio-hydrogen production yield capacity between asynchronous and simultaneous saccharification and fermentation processes from agricultural residue by mixed anaerobic cultures.

    Li, Yameng; Zhang, Zhiping; Zhu, Shengnan; Zhang, Huan; Zhang, Yang; Zhang, Tian; Zhang, Quanguo

    2018-01-01

    Taken common agricultural residues as substrate, dark fermentation bio-hydrogen yield capacity from asynchronous saccharification and fermentation (ASF) and simultaneous saccharification and fermentation (SSF) was investigated. The highest hydrogen yield of 472.75mL was achieved with corncob using ASF. Hydrogen yield from corn straw, rice straw, corncob and sorghum stalk by SSF were 20.54%,10.31%,13.99% and 5.92% higher than ASF, respectively. The experimental data fitted well to the modified Gompertz model. SSF offered a distinct advantage over ASF with respect to reducing overall process time (60h of SSF, 108h of ASF). Meanwhile, SSF performed better than SSF with respect to shortening the lag-stage. The major metabolites of anaerobic fermentation hydrogen production by ASF and SSF were butyric acid and acetic acid. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Comparison of muscle force production using the Smith machine and free weights for bench press and squat exercises.

    Cotterman, Michael L; Darby, Lynn A; Skelly, William A

    2005-02-01

    The Smith machine (SM) (vertical motion of bar on fixed path; fixed-form exercise) and free weights (FWs) (free-form path) are commonly used strength training modes. Exercisers may need to alternate between types of equipment, depending on testing, training, rehabilitation, and/or the exercisers' goals. The purposes of this study were to compare muscle force production for SM and FWs using a 1 repetition maximum (1RM) for the parallel back squat and supine bench press exercises and to predict the 1RM for one mode from 1RM on the other mode. Men (n = 16) and women (n = 16) alternately completed 1RM testing for squat and bench press using SM and FWs. Analyses of variance (type of equipment x sex) and linear regression models were calculated. A significant difference was found between bench press and squat 1RMs for each mode of equipment for all participants. The squat 1RM was greater for the SM than the FWs; conversely, the bench 1RM was greater for FWs than the SM. When sex was considered, bench 1RM for FWs was greater than SM for men and women. The squat 1RM was greater for SM than FWs for women only. The 1RM on one mode of equipment was the best predictor of 1RM for the other mode. For both sexes, the equation SM bench 1RM (in kilograms) = -6.76 + 0.95 (FW bench 1RM) can be used. For women only, SM squat 1RM (in kilograms) = 28.3 + 0.73 (FW squat 1RM). These findings provide equations for converting between SM and FW equipment for training.

  16. Bacterial carbohydrate-degrading capacity in foal faeces: changes from birth to pre-weaning and the impact of maternal supplementation with fermented feed products.

    Faubladier, Céline; Julliand, Véronique; Danel, Justine; Philippeau, Christelle

    2013-09-28

    The present study aimed at (1) describing age-related changes in faecal bacterial functional groups involved in carbohydrate degradation and in their activities in foals (n 10) from birth (day (d) 0) to 6 months (d180) and (2) investigating the effect of maternal supplementation (five mares per treatment) from d - 45 to d60 with fermented feed products on response trends over time of the foal bacterial carbohydratedegrading capacity. Maternal supplementation with fermented feed products stimulated foal growth from d0 to d60 and had an impact on the establishment of some digestive bacterial groups and their activities in foals from d0 to d5 but not in the longer term. Irrespective of the maternal treatment, total bacteria, total anaerobic, lactate-utilising and amylolytic bacteria were established immediately after birth (Panaerobes and lactate utilisers were established rapidly between d0 and d2 (P=0·021 and 0·066, respectively) and the increase in the percentage of propionate occurred earlier (P=0·013). Maternal supplementation had no effect on the establishment of fibrolytic bacteria and their activity. Cellulolytic bacteria and Fibrobacter succinogenes first appeared at d2 and d5, and increased progressively, reaching stable values at d30 and d60, respectively. From the second week of life, the increase in the molar percentage of acetate and the ratio (acetate + butyrate):propionate (P<0·05) suggested that fibrolytic activity had begun. From d60, only minor changes in bacterial composition and activities occurred, showing that the bacterial carbohydrate-degrading capacity was established at 2 months of age.

  17. What factors influence mitigative capacity?

    Winkler, Harald; Baumert, Kevin; Blanchard, Odile; Burch, Sarah; Robinson, John

    2007-01-01

    This article builds on Yohe's seminal piece on mitigative capacity, which elaborates 'determinants' of mitigative capacity, also reflected in the IPCC's third assessment report. We propose a revised definition, where mitigative capacity is a country's ability to reduce anthropogenic greenhouse gas emissions or enhance natural sinks. By 'ability' we mean skills, competencies, fitness, and proficiencies that a country has attained which can contribute to GHG emissions mitigation. A conceptual framework is proposed, linking mitigative capacity to a country's sustainable development path, and grouping the factors influencing mitigative capacity into three main sets: economic factors, institutional ones, and technology. Both quantitative and qualitative analysis of factors is presented, showing how these factors vary across countries. We suggest that it is the interplay between the three economic factors-income, abatement cost and opportunity cost-that shape mitigative capacity. We find that income is an important economic factor influencing mitigative capacity, while abatement cost is important in turning mitigative capacity into actual mitigation. Technology is a critical mitigative capacity, including the ability to absorb existing climate-friendly technologies or to develop innovative ones. Institutional factors that promote mitigative capacity include the effectiveness of government regulation, clear market rules, a skilled work force and public awareness. We briefly investigate such as high abatement cost or lack of political willingness that prevent mitigative capacity from being translated into mitigation

  18. 农业生产与水资源承载力评价%Agricultural production and evaluation in terms of water resources carrying capacity

    虞祎; 张晖; 胡浩

    2016-01-01

    AbstractBased on the evaluation of water resources carrying capacity, especially taking into account the impact of agricultural pollution on sustainable use of water resources, a comprehensive analysis was conducted on the strains of water resources due to farming and animal production in different regions of China to provide reference for rational estimation of potential agricultural growth and correct approaches for structural adjustments in agriculture. Excess nitrogen and grey water were calculated as indicators to quantify the impact of agricultural pollution on water resources. Following nutrient balance theory, excess nitrogen was the difference between the sum of nitrogen provided by chemical fertilizer, livestock manure and soil, and total nitrogen needed by farming. Grey water was the amount of water required for diluting excessively high concentration of nitrogen in water to a more environmental-friendly level. Agricultural water footprint was the sum of agricultural water and grey water used. The huge quantity of excess nitrogen produced by farming and livestock consequently led to excessive amount of grey water, which more than doubled the amount of water used in agriculture. There was therefore the need to reserve enough environmental space for diluting pollution when estimating water resources carrying capacity based on water sustainability and healthy development. Water surplus were constructed to reflect the potential of water resources to support agricultural production with detailed environmental consideration. Water surplus was the difference between water resources and agricultural water footprint. Using 2003-2012 nationwide samples, a panel data model was constructed to analyze the impact of change in sown area and livestock head on water surplus. The results suggested that the nationwide water in China could carry a maximum of 168.89 million hm2 or 3.57 billion pigs. The water resources carrying capacity model results also showed that the

  19. Force interaction and 3D pole movement in double poling.

    Stöggl, T; Holmberg, H-C

    2011-12-01

    The aim of this study was to analyze double poling using combined kinetic and 3D kinematic analysis at high skiing speeds as regards pole force components, pole angles and pole behavior during the poling and swing phase. The hypothesis was that a horizontal pole force is more predictive for maximal skiing speed (V(max)) than the resultant pole force. Sixteen elite skiers performed a double-poling V(max) test while treadmill roller skiing. Pole forces and 3D kinematics of pole movement at a speed of 30 km/h were analyzed and related to V(max). The duration of the "preparation phase" showed the strongest relationship with V(max) (r=0.87, Pmax) compared with the resultant pole force. Impact force was not related to V(max). At high skiing speeds, skiers should aim to combine high pole forces with appropriate timing of pole forces and appropriate pole and body positions during the swing and poling phase. The emphasis in training should be on the development of specific strength capacities for pole force production and the utilization of these capacities in double-poling training sessions. © 2011 John Wiley & Sons A/S.

  20. Exerting Capacity.

    Leger, J Michael; Phillips, Carolyn A

    2017-05-01

    Patient safety has been at the forefront of nursing research since the release of the Institute of Medicine's report estimating the number of preventable adverse events in hospital settings; yet no research to date has incorporated the perspectives of bedside nurses using classical grounded theory (CGT) methodology. This CGT study explored the perceptions of bedside registered nurses regarding patient safety in adult acute care hospitals. Data analysis used three techniques unique to CGT-the constant comparative method, coding, and memoing-to explore the values, realities, and beliefs of bedside nurses about patient safety. The analysis resulted in a substantive theory, Exerting Capacity, which explained how bedside nurses balance the demands of keeping their patients safe. Exerting Capacity has implications for health care organization leaders, nursing leaders, and bedside nurses; it also has indications for future research into the concept of patient safety.

  1. Comparison of different tests used in mapping the Greek virgin olive oil production for the determination of its total antioxidant capacity

    Georgiou, Constantinos A.

    2010-03-01

    Full Text Available This study aims to map the total antioxidant capacity (TAC of 50 Greek olive oil samples from the 2005-2006 season according to production region and cultivar and to compare the 2, 2’-azino-bis (3-ethylbenzo-thiazoline-6- sulfonic acid (ABTS, 2, 2-diphenyl-1-picrylhydrazyl radical (DPPH and Folin-Ciocalteu tests for use with olive oil. Antioxidant capacities determined in the hydrophilic fraction range between 5.42 - 22.5 mM gallic acid Kg-1 olive oil for the ABTS method and 1.29 - 9.95 mM Kg-1 for the DPPH method while in total, olive oil TAC ranges between 77 - 177 mM Kg-1 as assessed by the DPPH method. The results of total phenol content range between 3.8 and 29.4 mM Kg-1 olive oil. Total phenol content correlates with total antioxidant capacity assessed in the hydrophilic fraction through the DPPH (r = 0.89 and the ABTS (r = 0.69 assays. The hydrophilic fraction DPPH values correlate significantly with the ABTS values (r = 0.81. However, the DPPH values for total olive oil correlate poorly with the ABTS assay, the Folin-Ciocalteu method and the DPPH assay in hydrophilic fraction. Although total phenolic content shows good correlation with ABTS and DPPH values and could serve as a useful indicator for olive oil antioxidant capacity, the use of a battery of tests contributes to better characterization of the antioxidant capacity of olive oil.El objetivo de este estudio es el mapeo de la actividad antioxidante total (TAC de 50 aceites de oliva Griego de los años 2005-2006 de acuerdo a su región y cultivar, y se comparan los ensayos del ácido 2, 2’-azino-bis (3-etilbenzo-tiazolina- 6-sulfónico (ABTS, del 2,2-difenil-1-picrlhidrazil radical (DPPH y de Folin-Ciocalteu. La capacidad antioxidante determinada en la fracción hidrofílica varió entre 5.42-22.5 mM de ácido gálico Kg-1 de aceite para el método ABTS y 1.29- 9.95 mM Kg-1 de aceite para el método de DPPH mientras que la TAC del aceite de oliva completo varió entre 77-177 m

  2. Markets and Institutional Capacity

    Ingemann, Jan Holm

    2010-01-01

    Adequate explanations concerning the introduction of production and consumption of organic food in Denmark imply the necessity to engage a certain understanding of markets. Markets should subsequently not be seen as entities nor places but as complex relations between human actors. Further......, the establishment, maintenance and development of markets are depending on the capacity of the actors to enter into continuous and enhancing interplay....

  3. Optimization of dietary zinc for egg production and antioxidant capacity in Chinese egg-laying ducks fed a diet based on corn-wheat bran and soybean meal.

    Chen, W; Wang, S; Zhang, H X; Ruan, D; Xia, W G; Cui, Y Y; Zheng, C T; Lin, Y C

    2017-07-01

    The aim of this study was to evaluate the effect of zinc supplementation on productive performance and antioxidant status in laying ducks. Five-hundred-four laying ducks were divided into 7 treatments, each containing 6 replicates of 12 ducks. The ducks were caged individually and fed a corn-soybean meal and wheat bran basal diet (37 mg Zn/kg) or the basal diet supplemented with 15, 30, 45, 60, 75, or 90 mg Zn/kg (as zinc sulfate). During the early laying period of 10 d (daily egg production 80%). Average egg weight and feed intake did not differ among the groups of graded Zn supplementation.The egg quality was not affected by dietary Zn, including the egg shape index, Haugh unit, yolk color score, egg composition, and shell thickness. The activities of plasma activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GSH-PX) increased in a quadratic manner (P < 0.001) with increasing supplemental Zn. Plasma concentration of Zn increased quadratically (P < 0.05) as dietary Zn increased. The hepatic activity of Cu/Zn-SOD and GSH-PX increased quadratically (P < 0.05) with increasing dietary Zn. Plasma Zn concentrations were positively correlated with activities of T-SOD (P < 0.05), and positively with plasma Cu. Plasma concentration of reduced glutathione was correlated with plasma Cu. In conclusion, supplementation of Zn at 30 or 45 mg/kg to a corn-wheat bran and soybean basal diet may improve the productive performance and enhance the antioxidant capacity. © 2017 Poultry Science Association Inc.

  4. Acute effects of elastic bands during the free-weight barbell back squat exercise on velocity, power, and force production.

    Stevenson, Mark W; Warpeha, Joseph M; Dietz, Cal C; Giveans, Russell M; Erdman, Arthur G

    2010-11-01

    The use of elastic bands in resistance training has been reported to be effective in increasing performance-related parameters such as power, rate of force development (RFD), and velocity. The purpose of this study was to assess the following measures during the free-weight back squat exercise with and without elastic bands: peak and mean velocity in the eccentric and concentric phases (PV-E, PV-C, MV-E, MV-C), peak force (PF), peak power in the concentric phase, and RFD immediately before and after the zero-velocity point and in the concentric phase (RFDC). Twenty trained male volunteers (age = 26.0 ± 4.4 years) performed 3 sets of 3 repetitions of squats (at 55% one repetition maximum [1RM]) on 2 separate days: 1 day without bands and the other with bands in a randomized order. The added band force equaled 20% of the subjects' 55% 1RM. Two independent force platforms collected ground reaction force data, and a 9-camera motion capture system was used for displacement measurements. The results showed that PV-E and RFDC were significantly (p squats with elastic bands in terms of RFD. Practitioners concerned with improving RFD may want to consider incorporating this easily implemented training variation.

  5. Capacity Building

    Molloy, Brian; Mallick, Shahid

    2014-01-01

    Outcomes & Recommendations: • Significant increase needed in the nuclear workforce both to replace soon-to-retire current generation and to staff large numbers of new units planned • Key message, was the importance of an integrated approach to workforce development. • IAEA and other International Organisations were asked to continue to work on Knowledge Management, Networks and E&T activities • IAEA requested to conduct Global Survey of HR needs – survey initiated but only 50% of operating countries (30% of capacity) took part, so results inconclusive

  6. Incubating Isolated Mouse EDL Muscles with Creatine Improves Force Production and Twitch Kinetics in Fatigue Due to Reduction in Ionic Strength

    Head, Stewart I.; Greenaway, Bronwen; Chan, Stephen

    2011-01-01

    Background Creatine supplementation can improve performance during high intensity exercise in humans and improve muscle strength in certain myopathies. In this present study, we investigated the direct effects of acute creatine incubation on isolated mouse fast-twitch EDL muscles, and examined how these effects change with fatigue. Methods and Results The extensor digitorum longus muscle from mice aged 12–14 weeks was isolated and stimulated with field electrodes to measure force characteristics in 3 different states: (i) before fatigue; (ii) immediately after a fatigue protocol; and (iii) after recovery. These served as the control measurements for the muscle. The muscle was then incubated in a creatine solution and washed. The measurement of force characteristics in the 3 different states was then repeated. In un-fatigued muscle, creatine incubation increased the maximal tetanic force. In fatigued muscle, creatine treatment increased the force produced at all frequencies of stimulation. Incubation also increased the rate of twitch relaxation and twitch contraction in fatigued muscle. During repetitive fatiguing stimulation, creatine-treated muscles took 55.1±9.5% longer than control muscles to lose half of their original force. Measurement of weight changes showed that creatine incubation increased EDL muscle mass by 7%. Conclusion Acute creatine application improves force production in isolated fast-twitch EDL muscle, and these improvements are particularly apparent when the muscle is fatigued. One likely mechanism for this improvement is an increase in Ca2+ sensitivity of contractile proteins as a result of ionic strength decreases following creatine incubation. PMID:21850234

  7. Incubating isolated mouse EDL muscles with creatine improves force production and twitch kinetics in fatigue due to reduction in ionic strength.

    Stewart I Head

    Full Text Available BACKGROUND: Creatine supplementation can improve performance during high intensity exercise in humans and improve muscle strength in certain myopathies. In this present study, we investigated the direct effects of acute creatine incubation on isolated mouse fast-twitch EDL muscles, and examined how these effects change with fatigue. METHODS AND RESULTS: The extensor digitorum longus muscle from mice aged 12-14 weeks was isolated and stimulated with field electrodes to measure force characteristics in 3 different states: (i before fatigue; (ii immediately after a fatigue protocol; and (iii after recovery. These served as the control measurements for the muscle. The muscle was then incubated in a creatine solution and washed. The measurement of force characteristics in the 3 different states was then repeated. In un-fatigued muscle, creatine incubation increased the maximal tetanic force. In fatigued muscle, creatine treatment increased the force produced at all frequencies of stimulation. Incubation also increased the rate of twitch relaxation and twitch contraction in fatigued muscle. During repetitive fatiguing stimulation, creatine-treated muscles took 55.1±9.5% longer than control muscles to lose half of their original force. Measurement of weight changes showed that creatine incubation increased EDL muscle mass by 7%. CONCLUSION: Acute creatine application improves force production in isolated fast-twitch EDL muscle, and these improvements are particularly apparent when the muscle is fatigued. One likely mechanism for this improvement is an increase in Ca(2+ sensitivity of contractile proteins as a result of ionic strength decreases following creatine incubation.

  8. Variable Thumb Moment Arm Modeling and Thumb-Tip Force Production of a Human-Like Robotic Hand.

    Niehues, Taylor D; Deshpande, Ashish D

    2017-10-01

    The anatomically correct testbed (ACT) hand mechanically simulates the musculoskeletal structure of the fingers and thumb of the human hand. In this work, we analyze the muscle moment arms (MAs) and thumb-tip force vectors in the ACT thumb in order to compare the ACT thumb's mechanical structure to the human thumb. Motion data are used to determine joint angle-dependent MA models, and thumb-tip three-dimensional (3D) force vectors are experimentally analyzed when forces are applied to individual muscles. Results are presented for both a nominal ACT thumb model designed to match human MAs and an adjusted model that more closely replicates human-like thumb-tip forces. The results confirm that the ACT thumb is capable of faithfully representing human musculoskeletal structure and muscle functionality. Using the ACT hand as a physical simulation platform allows us to gain a better understanding of the underlying biomechanical and neuromuscular properties of the human hand to ultimately inform the design and control of robotic and prosthetic hands.

  9. Radio-capacity of ecosystems

    Kultakhmedov, Yu.; Kultakhmedova-Vyshnyakova, V.

    1997-01-01

    This paper consider a universal approach to ecosystems of different types, based on representation of their radio-capacity. The concept of ecosystem includes reproduction of components (bio-productivity) and conditions such as maintaining of environment quality. Radio-capacity in the case of radionuclide pollution appears in accumulation and redistribution of radionuclides in the ecosystem. As a result the radionuclides are redistributed and buried in soil or lake bottom sediments. Estimation models for the radio-capacity of water and terrestrial ecosystems are represented. The calculations of the radio-capacity factor of water ecosystems are performed, and the high radio-capacity of a freshwater reservoir (F=0.6-0.8) and extremely high radio-capacity of a reservoir cascade (F c =0.99) is shown material from the Dnieper's cascade reservoirs. The methods of radio-capacity estimation of agroecosystems, wood and marine ecosystems are developed. (authors)

  10. Limnology in El Dorado: some surprising aspects of the regulation of phytoplankton productive capacity in a high-altitude Andean lake (Laguna de Guatavita, Colombia).

    Donato, Jhon; Jimenez, Paola; Reynolds, Colin

    2012-09-01

    High-altitude mountain lakes remain understudied, mostly because of their relative inaccessibility. Laguna de Guatavita, a small, equatorial, high-altitude crater lake in the Eastern Range of the Colombian Andes, was once of high cultural importance to pre-Columban inhabitants, the original location of the legendary El Dorado. We investigated the factors regulating the primary production in Laguna de Guatavita (4degrees58'50" N - 73degrees46'43" W, alt. 2 935m.a.s.l., area: 0.11km2, maximum depth: 30m), during a series of three intensive field campaigns, which were conducted over a year-long period in 2003-2004. In each, standard profiles of temperature, oxygen concentration and light intensity were determined on each of 16-18 consecutive days. Samples were collected and analysed for chlorophyll and for biologically-significant solutes in GF/F-filtered water (NH4+, NO3(-), NO2(-); soluble reactive phosphorus). Primary production was also determined, by oxygen generation, on each day of the campaign. Our results showed that the productive potential of the lake was typically modest (campaign averages of 45-90mg C/m2.h) but that many of the regulating factors were not those anticipated intuitively. The lake is demonstrably meromictic, reminiscent ofkarstic dolines in higher latitudes, its stratification being maintained by solute- concentration gradients. Light penetration is poor, attributable to the turbidity owing to fine calcite and other particulates in suspension. Net primary production in the mixolimnion of Laguna de Guavita is sensitive to day-to-day variations in solar irradiance at the surface. However, deficiencies in nutrient availability, especially nitrogen, also constrain the capacity of the lake to support a phytoplankton. We deduced that Laguna de Guatavita is something of a limnological enigma, atypical of the common anticipation of a "mountain lake". While doubtlessly not unique, comparable descriptions of similar sites elsewhere are sufficiently

  11. Comparison of the Relationship between Lying and Standing Ultrasonography Measures of Muscle Morphology with Isometric and Dynamic Force Production Capabilities

    John P. Wagle

    2017-11-01

    Full Text Available The purpose of the current study was (1 to examine the differences between standing and lying measures of vastus lateralis (VL, muscle thickness (MT, pennation angle (PA, and cross-sectional area (CSA using ultrasonography; and (2 to explore the relationships between lying and standing measures with isometric and dynamic assessments of force production—specifically peak force, rate of force development (RFD, impulse, and one-repetition maximum back squat. Fourteen resistance-trained subjects (age = 26.8 ± 4.0 years, height = 181.4 ± 6.0 cm, body mass = 89.8 ± 10.7 kg, back squat to body mass ratio = 1.84 ± 0.34 agreed to participate. Lying and standing ultrasonography images of the right VL were collected following 48 hours of rest. Isometric squat assessments followed ultrasonography, and were performed on force platforms with data used to determine isometric peak force (IPF, as well as RFD and impulse at various time points. Forty-eight hours later, one-repetition maximum back squats were performed by each subject. Paired-samples t-tests revealed statistically significant differences between standing and lying measurements of MT (p < 0.001, PA (p < 0.001, and CSA (p ≤ 0.05, with standing values larger in all cases. Further, standing measures were correlated more strongly and abundantly to isometric and dynamic performance. These results suggest that if practitioners intend to gain insight into strength-power potential based on ultrasonography measurements, performing the measurement collection with the athlete in a standing posture may be preferred.

  12. Integrated capacity and inventory management with capacity acquisition lead times

    Mincsovics, G.Z.; Tan, T.; Alp, O.

    2009-01-01

    We model a make-to-stock production system that utilizes permanent and contingent capacity to meet non-stationary stochastic demand, where a constant lead time is associated with the acquisition of contingent capacity. We determine the structure of the optimal solution concerning both the

  13. The production of Parmigiano-Reggiano cheese : the force of an artisanal system in an industrialised world

    Roest, de K.

    2000-01-01

    In many respects the Parmigiano-Reggiano production system is a unique dairy system. The processing of 1.35 million tons of milk into a high quality product in 600 small cheese dairies using predominantly artisan production techniques is not found anywhere else in Europe. The high labour

  14. A interdependência entre sistemas de controle de produção e critérios de alocação de capacidades The relationship between production planning and control systems and methods of capacity allocation

    Fernando Bernardi de Souza

    2002-08-01

    Full Text Available Há uma aparente carência de pesquisas sobre os inter-relacionamentos entre critérios de alocação de capacidades de recursos de manufatura e os métodos de controle de produção. Estudos sobre alocação de capacidades se baseiam geralmente em sistemas simplificados de empurrar a produção, desconsiderando sistemas mais atuais de gestão de produção. Por outro lado, pesquisas sobre a aplicabilidade de sistemas de gestão da produção não consideram apropriada a maneira como as capacidades produtivas dos recursos estão alocadas ao longo da linha. Analisar as interdependências entre esses dois grandes ramos de pesquisa é o objetivo deste artigo.There is a lack of researches on the relationship between methods of capacity allocation of manufacturing resources and production planning and control systems. Studies about capacity allocation are based on simplified push production systems not considering more current production management systems. By other side, studies about efficiency of production management systems don't consider the effect of different criteria of capacity allocation of manufacturing resources at the results. The purpose of this paper is to investigate how the different policies of capacity allocation and different production planning and control systems interrelate between each other.

  15. Informing the scale-up of Kenya’s nursing workforce: a mixed methods study of factors affecting pre-service training capacity and production

    2014-01-01

    Background Given the global nursing shortage and investments to scale-up the workforce, this study evaluated trends in annual student nurse enrolment, pre-service attrition between enrolment and registration, and factors that influence nurse production in Kenya. Methods This study used a mixed methods approach with data from the Regulatory Human Resources Information System (tracks initial student enrolment through registration) and the Kenya Health Workforce Information System (tracks deployment and demographic information on licensed nurses) for the quantitative analyses and qualitative data from key informant interviews with nurse training institution educators and/or administrators. Trends in annual student nurse enrolment from 1999 to 2010 were analyzed using regulatory and demographic data. To assess pre-service attrition between training enrolment and registration with the nursing council, data for a cohort that enrolled in training from 1999 to 2004 and completed training by 2010 was analyzed. Multivariate logistic regression was used to test for factors that significantly affected attrition. To assess the capacity of nurse training institutions for scale-up, qualitative data was obtained through key informant interviews. Results From 1999 to 2010, 23,350 students enrolled in nurse training in Kenya. While annual new student enrolment doubled between 1999 (1,493) and 2010 (3,030), training institutions reported challenges in their capacity to accommodate the increased numbers. Key factors identified by the nursing faculty included congestion at clinical placement sites, limited clinical mentorship by qualified nurses, challenges with faculty recruitment and retention, and inadequate student housing, transportation and classroom space. Pre-service attrition among the cohort that enrolled between 1999 and 2004 and completed training by 2010 was found to be low (6%). Conclusion To scale-up the nursing workforce in Kenya, concurrent investments in expanding the

  16. Subatomic forces

    Sutton, C.

    1989-01-01

    Inside the atom, particles interact through two forces which are never felt in the everyday world. But they may hold the key to the Universe. These ideas on subatomic forces are discussed with respect to the strong force, the electromagnetic force and the electroweak force. (author)

  17. Reclaimed water as a main resource to enhance the adaptive capacity to climate change in semi-arid Mediterranean agricultural areas using Earth Observation products

    Pavia Rico, Ana; Lopez-Baeza, Ernesto; Matieu, Pierre-Philippe; Hernandez Sancho, Francesc; Loarte, Edwin

    Lack of water is being a big problem in semi-arid areas to make agricultural profits. Most of Mediterranean countries like Spain, Italy, Greece or Cyprus and other countries like Morocco, the Arab United Emirates, South-American countries or China are starting to reuse wastewater as adaptation to climate change water scarcity. Drought areas are nowadays increasing, thus making fertile areas unproductive. For this reason, the European trend is to work on reusing wastewater as a solution to water scarcity in agriculture. Moreover, since population is growing fast, wastewater production is increasing as well as drinkable water demand, thus making reclaimed water as the water guarantee for irrigation and better agricultural management. This work represents a preliminary initiative to check, analyse and monitor the land by using remote sensing techniques to identify and determine the potential lands that used to be productive in the past, are now abandoned, and we want to recuperate to obtain socio-economic benefits. On top of this, this initiative will clearly enhance the adaption capacity of rural/agricultural lands to climate change. Alternatively to reclaimed water, greenhouses, desalination plants or transboarding water do not really eliminate the problem but only offer a temporary solution, make spending plenty of money and always provoking irreversible damages to the environment. The pilot area to first develop this research is the Valencia and Murcia Autonomous Communities located in the Spanish Mediterranean Coastline. An added value of this work will be to develop a methodology transferable to other potential countries with similar climatic characteristics and difficulties for irrigation, by using remote sensing methods and techniques. The remote sensing products obtained provide full information about the current state of the potential lands to grow crops. Potential areas are then being selected to carry out a socio-economic analysis leading to: (i

  18. Analysis of coolability of the control rods of a Savannah River Site production reactor with loss of normal forced convection cooling

    Easterling, T.C.; Hightower, N.T.; Smith, D.C.; Amos, C.N.

    1992-01-01

    An analytical study of the coolability of the control rods in the Savannah River Site (SRS) K-Production Reactor under conditions of loss of normal forced convection cooling has been performed. The study was performed as part of the overall safety analysis of the reactor supporting its restart. The analysis addresses the buoyancy-driven flow over the control rods that occurs when forced cooling is lost, and the limit of critical heat flux that sets the acceptance criteria for the study. The objective of the study is to demonstrate that the control rods will remain cooled at powers representative of those anticipated for restart of the reactor. The study accomplishes this objective with a very tractable simplified analysis for the modest restart power. In addition, a best-estimate calculation is performed, and the results are compared to results from sub-scale scoping experiments. 5 refs

  19. Using Market Forces to Reduce Greenhouse Gas Emissions Through Product-Level Life Cycle Analysis and Eco-Labeling

    Sweeney, J. F.; Davis, S. J.

    2007-12-01

    Established protocols allow entity-level accounting of greenhouse gas (GHG) emissions. The information contained within GHG inventories is used by entities to manage their carbon footprint and to anticipate future exposure to compulsory GHG markets or taxes. The efficacy of such inventories, as experienced by the consumer, can be improved upon by product-level GHG inventories applying the methods of traditional life cycle analysis (LCA). A voluntary product-level assessment of this type, coupled with an eco-label, would 1) empower consumers with information about the total embodied GHG content of a product, 2) allow companies to understand and manage GHG emissions outside the narrow scope of their entities, and 3) drive reduction of GHG emissions throughout product value chains. The Climate Conservancy (TCC) is a non-profit organization founded to help companies calculate their GHG emissions at the level of individual product units, and to inform consumers about the GHG intensity of the products they choose to purchase. With the assistance of economists, policy experts and scientists, TCC has developed a useful metric for reporting product-level GHG emissions that allows for a normalized comparison of a product's GHG intensity irrespective of industry sector or competitors, where GHG data are often unavailable or incomplete. Using this metric, we envision our Climate Conscious label becoming an important arbiter of choice for consumers seeking ways to mitigate their climate impacts without the need for governmental regulation.

  20. Net Acid Production, Acid Neutralizing Capacity, and Associated Mineralogical and Geochemical Characteristics of Animas River Watershed Igneous Rocks Near Silverton, Colorado

    Yager, Douglas B.; Choate, LaDonna; Stanton, Mark R.

    2008-01-01

    This report presents results from laboratory and field studies involving the net acid production (NAP), acid neutralizing capacity (ANC), and magnetic mineralogy of 27 samples collected in altered volcanic terrain in the upper Animas River watershed near Silverton, Colo., during the summer of 2005. Sampling focused mainly on the volumetrically important, Tertiary-age volcanic and plutonic rocks that host base- and precious-metal mineralization in the study area. These rocks were analyzed to determine their potential for neutralization of acid-rock drainage. Rocks in the study area have been subjected to a regional propylitic alteration event, which introduced calcite, chlorite (clinochlore), and epidote that have varying amounts and rates of acid neutralizing capacity (ANC). Locally, hydrothermal alteration has consumed any ANC and introduced minerals, mainly pyrite, that have a high net acid production (NAP). Laboratory studies included hydrogen pyroxide (H2O2) acid digestion and subsequent sodium hydroxide (NaOH) titration to determine NAP, and sulfuric acid (H2SO4) acid titration experiments to determine ANC. In addition to these environmental rock-property determinations, mineralogical, chemical, and petrographic characteristics of each sample were determined through semiquantitative X-ray diffractometry (Rietveld method), optical mineralogy, wavelength dispersive X-ray fluorescence, total carbon-carbonate, and inductively coupled plasma?mass spectrometric analysis. An ANC ranking was assigned to rock samples based on calculated ANC quantity in kilograms/ton (kg/t) calcium carbonate equivalent and ratios of ANC to NAP. Results show that talus near the southeast Silverton caldera margin, composed of andesite clasts of the Burns Member of the Silverton Volcanics, has the highest ANC (>100 kg/t calcium carbonate equivalent) with little to no NAP. The other units found to have moderate to high ANC include (a) andesite lavas and volcaniclastic rocks of the San Juan

  1. Analysis of cardiovascular system responses to forced vital capacity in COPD Análise das respostas do sistema cardiovascular ao teste de capacidade vital forçada na DPOC

    Felipe A. R. Mendes

    2011-04-01

    Full Text Available BACKGROUND: The forced vital capacity (FVC test is routinely performed to evaluate pulmonary function in patients with chronic obstructive pulmonary disease (COPD. However, the influence of the FVC maneuver on the cardiovascular system of patients with COPD is poorly understood. OBJECTIVES: To analyze the behavior of heart rate (HR, blood pressure (BP and heart rate variability (HRV during the FVC test in COPD patients. METHODS: Nineteen men with COPD (72±7 years, GOLD stage I=3, II=5, III=7 and IV=4 patients performed the FVC test while having their HR monitored. HRV was assessed in time (rMSSD and frequency domains (LF, HF and LF/HF at rest, before and after the best FVC maneuver. BP was measured at rest, immediately before and at the end of the test, as well as 10 minutes after the end of the test. RESULTS: At the beginning of the FVC maneuver, HR decreased (pCONTEXTUALIZAÇÃO: O teste de capacidade vital forçada (CVF é rotineiramente realizado na avaliação da função pulmonar de pacientes com doença pulmonar obstrutiva crônica (DPOC. Entretanto, permanece pouco compreendida a influência do teste de CVF sobre o sistema cardiovascular de pacientes com DPOC. OBJETIVOS: Analisar o comportamento da frequência cardíaca (FC, pressão arterial (PA e variabilidade da frequência cardíaca (VFC no teste de CVF na DPOC. MÉTODOS: Dezenove homens com DPOC (72 ± 7 anos, no estágio de gravidade GOLD I=3, II=5, III=7 e IV=4 pacientes realizaram a manobra de CVF e tiveram sua FC monitorada durante todo o exame, e a VFC analisada nos domínios do tempo (rMSSD e da frequência (BF, AF e BF/AF durante o repouso, antes e após a melhor manobra de CVF. A PA foi analisada no repouso, imediatamente ao final da manobra de CVF e 10 minutos após o término de todos os testes. RESULTADOS: Ao início da manobra de CVF, a FC reduziu (p<0,001 e, em seguida, aumentou progressivamente até o final do teste (p<0,001. Após término da manobra, a FC continuou

  2. Multi-Capacity Load Cell Concept

    Seif. M. OSMAN

    2014-09-01

    Full Text Available Force measuring systems are usually used to calibrate force generated systems, it is not preferable to use load cells to measure forces less than 10 % of its nominal capacity. Several load cells are required to offer calibration facilities at sites to cover different ranges, this lead to difficulties in handling procedures, through the need for several carrying cases to carry this overweight in addition to the over cost of purchasing several load cells. This article concerns with introducing a new concept for designing a multi-capacity load cell as a new force standard in the field of measuring the force. This multi-capacity load cell will replace a set of load cells and reflects economically on the total cost and on easiness of handling procedures.

  3. Climate Forcing Datasets for Agricultural Modeling: Merged Products for Gap-Filling and Historical Climate Series Estimation

    Ruane, Alex C.; Goldberg, Richard; Chryssanthacopoulos, James

    2014-01-01

    The AgMERRA and AgCFSR climate forcing datasets provide daily, high-resolution, continuous, meteorological series over the 1980-2010 period designed for applications examining the agricultural impacts of climate variability and climate change. These datasets combine daily resolution data from retrospective analyses (the Modern-Era Retrospective Analysis for Research and Applications, MERRA, and the Climate Forecast System Reanalysis, CFSR) with in situ and remotely-sensed observational datasets for temperature, precipitation, and solar radiation, leading to substantial reductions in bias in comparison to a network of 2324 agricultural-region stations from the Hadley Integrated Surface Dataset (HadISD). Results compare favorably against the original reanalyses as well as the leading climate forcing datasets (Princeton, WFD, WFD-EI, and GRASP), and AgMERRA distinguishes itself with substantially improved representation of daily precipitation distributions and extreme events owing to its use of the MERRA-Land dataset. These datasets also peg relative humidity to the maximum temperature time of day, allowing for more accurate representation of the diurnal cycle of near-surface moisture in agricultural models. AgMERRA and AgCFSR enable a number of ongoing investigations in the Agricultural Model Intercomparison and Improvement Project (AgMIP) and related research networks, and may be used to fill gaps in historical observations as well as a basis for the generation of future climate scenarios.

  4. Exciplexes versus Loose Ion Pairs: How Does the Driving Force Impact the Initial Product Ratio of Photoinduced Charge Separation Reactions?

    2014-01-01

    Many donor–acceptor systems can undergo a photoinduced charge separation reaction, yielding loose ion pairs (LIPs). LIPs can be formed either directly via (distant) electron transfer (ET) or indirectly via the dissociation of an initially formed exciplex or tight ion pair. Establishing the prevalence of one of the reaction pathways is challenging because differentiating initially formed exciplexes from LIPs is difficult due to similar spectroscopic footprints. Hence, no comprehensive reaction model has been established for moderately polar solvents. Here, we employ an approach based on the time-resolved magnetic field effect (MFE) of the delayed exciplex luminescence to distinguish the two reaction channels. We focus on the effects of the driving force of ET and the solvent permittivity. We show that, surprisingly, the exciplex channel is significant even for an exergonic ET system with a free energy of ET of −0.58 eV and for the most polar solutions studied (butyronitrile). Our findings demonstrate that exciplexes play a crucial role even in polar solvents and at moderate driving forces, contrary to what is usually assumed. PMID:25243054

  5. Unveiling aerosol-cloud interactions - Part 1: Cloud contamination in satellite products enhances the aerosol indirect forcing estimate

    Christensen, Matthew W.; Neubauer, David; Poulsen, Caroline A.; Thomas, Gareth E.; McGarragh, Gregory R.; Povey, Adam C.; Proud, Simon R.; Grainger, Roy G.

    2017-11-01

    Increased concentrations of aerosol can enhance the albedo of warm low-level cloud. Accurately quantifying this relationship from space is challenging due in part to contamination of aerosol statistics near clouds. Aerosol retrievals near clouds can be influenced by stray cloud particles in areas assumed to be cloud-free, particle swelling by humidification, shadows and enhanced scattering into the aerosol field from (3-D radiative transfer) clouds. To screen for this contamination we have developed a new cloud-aerosol pairing algorithm (CAPA) to link cloud observations to the nearest aerosol retrieval within the satellite image. The distance between each aerosol retrieval and nearest cloud is also computed in CAPA. Results from two independent satellite imagers, the Advanced Along-Track Scanning Radiometer (AATSR) and Moderate Resolution Imaging Spectroradiometer (MODIS), show a marked reduction in the strength of the intrinsic aerosol indirect radiative forcing when selecting aerosol pairs that are located farther away from the clouds (-0.28±0.26 W m-2) compared to those including pairs that are within 15 km of the nearest cloud (-0.49±0.18 W m-2). The larger aerosol optical depths in closer proximity to cloud artificially enhance the relationship between aerosol-loading, cloud albedo, and cloud fraction. These results suggest that previous satellite-based radiative forcing estimates represented in key climate reports may be exaggerated due to the inclusion of retrieval artefacts in the aerosol located near clouds.

  6. The effect of swinging the arms on muscle activation and production of leg force during ski skating at different skiing speeds.

    Göpfert, Caroline; Lindinger, Stefan J; Ohtonen, Olli; Rapp, Walter; Müller, Erich; Linnamo, Vesa

    2016-06-01

    The study investigated the effects of arm swing during leg push-off in V2-alternate/G4 skating on neuromuscular activation and force production by the leg muscles. Nine skilled cross-country skiers performed V2-alternate skating without poles at moderate, high, and maximal speeds, both with free (SWING) and restricted arm swing (NOSWING). Maximal speed was 5% greater in SWING (P<0.01), while neuromuscular activation and produced forces did not differ between techniques. At both moderate and high speed the maximal (2% and 5%, respectively) and average (both 5%) vertical force and associated impulse (10% and 14%) were greater with SWING (all P<0.05). At high speed range of motion and angular velocity of knee flexion were 24% greater with SWING (both P<0.05), while average EMG of m. biceps femoris was 31% lower (all P<0.05) in SWING. In a similar manner, the average EMG of m. vastus medialis and m. biceps femoris were lower (17% and 32%, P<0.05) during the following knee extension. Thus, swinging the arms while performing V2-alternate can enhance both maximal speed and skiing economy at moderate and, in particularly, high speeds. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. ESI-MSn and LC-ESI-MS studies to characterize forced degradation products of bosentan and a validated stability-indicating LC-UV method.

    Bansal, Gulshan; Singh, Ranjit; Saini, Balraj; Bansal, Yogita

    2013-01-01

    The present study reports the characterization of forced degradation products of bosentan and a validated stability-indicating HPLC method for the stability testing of bosentan tablets. The forced degradation was carried out under the conditions of hydrolysis, oxidation, dry heat and photolysis. The drug was found unstable in acid, alkali and oxidative media whereas stable to the hydrolysis in water, to dry heat and to photolysis. In total, six degradation products were formed in all conditions which were resolved in a single run on a C-18 column with gradient elution using ammonium acetate buffer (pH 4.5, 5.0mM), methanol and acetonitrile. Structures of all the degradation products were characterized through +ESI-MS(n) and LC-ESI-MS spectral data of bosentan as well as LC-ESI-MS spectral data of the products. The products II-VI were characterized as 6-amino-[2,2']bipyrimidinyl-4,5-diol, 6-amino-5-(2-methoxyphenoxy)-[2,2']-bipyrimidinyl-4-ol, 2-[6-amino-5-(2-methoxyphenoxy)-[2,2']-bipyrimidinyl-4-yloxy]-ethanol, 4-tert-butyl-N-[6-(1-methoxyethoxy)-5-(2-methoxyphenoxy)-[2,2']-bipyrimidinyl-4-yl]-benzenesulfonamide and 4-tert-butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide, respectively. The peak of the product I was found to be due to two secondary degradation products which co-eluted and were characterized as β-hydroxyethyl p-tert-butylphenylsulfonate (Ia) and 2-[2-(2-hydroxyethoxy)-phenoxy]-ethanol (Ib). These products were formed due to hydrolysis of sulfonamide and alkylaryl ether and the diaryl ether linkages as well as dehydration of the primary alcohol group. The most probable degradation mechanisms were proposed. The HPLC method was found to be stability-indicating, linear (2-100 μg ml(-1)), accurate, precise, sensitive, specific, rugged and robust for quantitation of the drug. The method was applied to the stability testing of the commercially available bosentan tablets successfully. Copyright © 2012 Elsevier B.V. All

  8. Targeted inhibition of TGF-β results in an initial improvement but long-term deficit in force production after contraction-induced skeletal muscle injury.

    Gumucio, Jonathan P; Flood, Michael D; Phan, Anthony C; Brooks, Susan V; Mendias, Christopher L

    2013-08-15

    Transforming growth factor-β (TGF-β) is a proinflammatory cytokine that regulates the response of many tissues following injury. Previous studies in our lab have shown that treating muscles with TGF-β results in a dramatic accumulation of type I collagen, substantial fiber atrophy, and a marked decrease in force production. Because TGF-β promotes atrophy and fibrosis, our objective was to investigate whether the inhibition of TGF-β after injury would enhance the recovery of muscle following injury. We hypothesized that inhibiting TGF-β after contraction-induced injury would improve the functional recovery of muscles by preventing muscle fiber atrophy and weakness, and by limiting the accumulation of fibrotic scar tissue. To test this hypothesis, we induced an injury using a series of in situ lengthening contractions to extensor digitorum longus muscles of mice treated with either a bioneutralizing antibody against TGF-β or a sham antibody. Compared with controls, muscles from mice receiving TGF-β inhibitor showed a greater recovery in force 3 days and 7 days after injury but had a decrease in force compared with controls at the 21-day time point. The early enhancement in force in the TGF-β inhibitor group was associated with an initial improvement in tissue morphology, but, at 21 days, while the control group was fully recovered, the TGF-β inhibitor group displayed an irregular extracellular matrix and an increase in atrogin-1 gene expression. These results indicate that the inhibition of TGF-β promotes the early recovery of muscle function but is detrimental overall to full muscle recovery following moderate to severe muscle injuries.

  9. Modulation of frontogenetic plankton production along a meandering jet by zonal wind forcing: An application to the Alboran Sea

    Oguz, Temel; Mourre, Baptiste; Tintoré, Joaquin

    2017-08-01

    We present a coupled physical-biological modeling study to elucidate the changes in ageostrophic frontal dynamics and the frontogenetic plankton production characteristics of a meandering jet under the impacts of successive westerly/easterly wind events combined with seasonal variations in the upstream transport and buoyancy flux characteristics of the jet, using a case study for the Alboran Sea (Western Mediterranean). Their nonlinear coupling is shown to result in different forms of physical and biological characteristics of the background jet structure that follows a meandering path around two anticyclonic gyres in the western and eastern basins and a cyclonic eddy in between. The westerly, downfront wind events broaden the jet, and result in stronger cross-frontal density contrast and intensify ageostrophic cross-frontal secondary circulation. Thus, they improve the frontogenetic plankton production with respect to the no-wind case. They also support higher production along the northern coast in response to wind-induced coastal upwelling and spreading of resulting nutrient-rich, productive water by mesoscale stirring. These features weaken gradually as the jet transport reduces. In contrast, stronger and longer-lasting easterlies during the reduced jet transport phase weaken the currents and frontal density structure, change the circular Western Alboran Gyre to an elongated form, and shift the main axis of the jet towards the southern basin. Then, frontogenesis fails to contribute to phytoplankton production that becomes limited to the eddy pumping within cyclones. Apart from the frontogenetic production, eddy pumping, mesoscale stirring, and diapycnal mixing of nutrients support intermittent and localized phytoplankton patches over the basin.

  10. Effect of tendon vibration during wide-pulse neuromuscular electrical stimulation (NMES) on muscle force production in people with spinal cord injury (SCI).

    Bochkezanian, Vanesa; Newton, Robert U; Trajano, Gabriel S; Vieira, Amilton; Pulverenti, Timothy S; Blazevich, Anthony J

    2018-02-13

    Neuromuscular electrical stimulation (NMES) is commonly used in skeletal muscles in people with spinal cord injury (SCI) with the aim of increasing muscle recruitment and thus muscle force production. NMES has been conventionally used in clinical practice as functional electrical stimulation (FES), using low levels of evoked force that cannot optimally stimulate muscular strength and mass improvements, and thus trigger musculoskeletal changes in paralysed muscles. The use of high intensity intermittent NMES training using wide-pulse width and moderate-intensity as a strength training tool could be a promising method to increase muscle force production in people with SCI. However, this type of protocol has not been clinically adopted because it may generate rapid muscle fatigue and thus prevent the performance of repeated high-intensity muscular contractions in paralysed muscles. Moreover, superimposing patellar tendon vibration onto the wide-pulse width NMES has been shown to elicit further increases in impulse or, at least, reduce the rate of fatigue in repeated contractions in able-bodied populations, but there is a lack of evidence to support this argument in people with SCI. Nine people with SCI received two NMES protocols with and without superimposing patellar tendon vibration on different days (i.e. STIM and STIM+vib), which consisted of repeated 30 Hz trains of 58 wide-pulse width (1000 μs) symmetric biphasic pulses (0.033-s inter-pulse interval; 2 s stimulation train; 2-s inter-train interval) being delivered to the dominant quadriceps femoris. Starting torque was 20% of maximal doublet-twitch torque and stimulations continued until torque declined to 50% of the starting torque. Total knee extensor impulse was calculated as the primary outcome variable. Total knee extensor impulse increased in four subjects when patellar tendon vibration was imposed (59.2 ± 15.8%) but decreased in five subjects (- 31.3 ± 25.7%). However, there were no

  11. Verifying Operational and Developmental Air Force Weather Cloud Analysis and Forecast Products Using Lidar Data from Department of Energy Atmospheric Radiation Measurement (ARM) Sites

    Hildebrand, E. P.

    2017-12-01

    Air Force Weather has developed various cloud analysis and forecast products designed to support global Department of Defense (DoD) missions. A World-Wide Merged Cloud Analysis (WWMCA) and short term Advected Cloud (ADVCLD) forecast is generated hourly using data from 16 geostationary and polar-orbiting satellites. Additionally, WWMCA and Numerical Weather Prediction (NWP) data are used in a statistical long-term (out to five days) cloud forecast model known as the Diagnostic Cloud Forecast (DCF). The WWMCA and ADVCLD are generated on the same polar stereographic 24 km grid for each hemisphere, whereas the DCF is generated on the same grid as its parent NWP model. When verifying the cloud forecast models, the goal is to understand not only the ability to detect cloud, but also the ability to assign it to the correct vertical layer. ADVCLD and DCF forecasts traditionally have been verified using WWMCA data as truth, but this might over-inflate the performance of those models because WWMCA also is a primary input dataset for those models. Because of this, in recent years, a WWMCA Reanalysis product has been developed, but this too is not a fully independent dataset. This year, work has been done to incorporate data from external, independent sources to verify not only the cloud forecast products, but the WWMCA data itself. One such dataset that has been useful for examining the 3-D performance of the cloud analysis and forecast models is Atmospheric Radiation Measurement (ARM) data from various sites around the globe. This presentation will focus on the use of the Department of Energy (DoE) ARM data to verify Air Force Weather cloud analysis and forecast products. Results will be presented to show relative strengths and weaknesses of the analyses and forecasts.

  12. Capacity competition in electricity markets

    Crampes, Claude; Creti, Anna

    2005-01-01

    The article analyzed a two-stage game where capacity constrained electricity generators first choose how much capacity they make available and then compete in a uniform-rice auction. It is studied how capacity withholding can be used strategically to enforce market power and how uniform auctions in the price game change the results of capacity constrained competition models. The uniform auction procedure gives strong incentives to capacity restriction. At equilibrium, however, power shortage never occurs. Though auctions in electricity markets have already been studied by several economists, yet an important feature of spot trading is the capacity availability decision. In fact, for technical reasons, such as equipment maintenance or failures, the installed capacity may not work at maximum operating level and the spot market rules oblige generators to announce which plants they are willing to use and simultaneously their offer prices. Beside technical reasons, the so-called 'capacity declarations' also offer a strategic instrument for firms: by restricting capacity, operators can benefit from scarcity rents. Assessing whether generators withhold capacity is an intriguing issue for real electricity markets, though proving it is a difficult task. Several theoretical papers show that generators are able to keep wholesale prices high as compared to their generation costs. In our model, a generator is not obliged to declare all installed capacity as available, but decides on the amount of MW of electricity that is available. Hence the available capacity is an endogenous variable while the installed one is exogenous. The distinction between installed capacities and 'available' capacities allows to explain clearly whether generators exert market power by declaring unavailable some production units. Although we find multiple sub game perfect equilibria that cannot be eliminated by Pareto-dominance, all the outcomes are characterized by market price at the highest

  13. Determinação da capacidade real necessária de um processo produtivo utilizando cadeia de Markov Determination of necessary real capacity in productive process using Markov chain

    Francielly Hedler Staudt

    2011-01-01

    Full Text Available Todas as empresas em desenvolvimento passam pelo momento de decidir se há ou não necessidade de realizar novos investimentos para suprir uma demanda crescente. Para tomar tal decisão é imprescindível conhecer se o processo atual tem capacidade de produzir a nova demanda. Porém, são raras as empresas que têm a percepção de que os refugos e retrabalhos também consomem recursos da produção e, portanto, devem ser considerados no cálculo da capacidade produtiva. A proposta deste trabalho consiste em incluir esses fatores na análise de capacidade da fábrica, utilizando uma matriz de transição estocástica da cadeia absorvente de Markov como ferramenta para obtenção do fator de capacidade. Este fator, aliado ao índice de eficiência e a demanda desejada ao fim do processo, resulta na capacidade real necessária. Um estudo de caso exemplifica a metodologia, apresentando resultados que permitem o cálculo do índice de ocupação real de cada centro produtivo. O cálculo desse índice demonstrou que alguns centros de trabalho necessitam de análises sobre investimentos em capacitação, pois ultrapassaram 90% de ocupação.All developing companies must decide once in a while whether it is required to perform new investments to handle a growing demand. In order to make this decision, it is essential to know whether the current productive capacity is able to supply the new demand. However, just few companies realize that refuse and rework use production resources, which must be taken into account in the productive capacity calculation. The aim of this work was to include these factors in factory capacity analysis, using Markov chain stochastic transition matrix as a tool to obtain the capacity factor. This factor - used together with the efficiency index and the required demand in the end of the process - results in the necessary real capacity. A case study exemplifies the proposed methodology, presenting results that allow for the

  14. Reconstruction actions carried out in order to achieve nominal design heat capacity of hot water boilers type VKSM 40; A product of TPK-Zagreb

    Ninevski, Gjorgji; Sekovanikj, Ivica

    2000-01-01

    Hot water boilers with a steep turbines membranous produced by TPK-Zagreb in 1979 are projected for nominal capacity of 46.52 MW. But it was demonstrated in practice, according the performed measurements, that during the exploitation they do not give declared thermal power. In this article the chronological review of all successful performed reconstructive operations by engineering staff from Toplifikacija Joint-Stock Co. for district heating -Skopje (Macedonia) on the hot water boilers type VKSM40 with nominal capacity of 46.52 MW is given. (Authors)

  15. The productivity of physician assistants and nurse practitioners and health work force policy in the era of managed health care.

    Scheffler, R M; Waitzman, N J; Hillman, J M

    1996-01-01

    Managed care is spreading rapidly in the United States and creating incentives for physician practices to find the most efficient combination of health professionals to deliver care to an enrolled population. Given these trends, it is appropriate to reexamine the roles of physician assistants (PAs) and nurse practitioners (NPs) in the health care workforce. This paper briefly reviews the literature on PA and NP productivity, managed care plans' use of PAs and NPs, and the potential impact of PAs and NPs on the size and composition of the future physician workforce. In general, the literature supports the idea that PAs and NPs could have a major impact on the future health care workforce. Studies show significant opportunities for increased physician substitution and even conservative assumptions about physician task delegation imply a large increase in the number of PAs and NPs that can be effectively deployed. However, the current literature has certain limitations that make it difficult to quantify the future impact of PAs and NPs. Among these limitations is the fact that virtually all formal productivity studies were conducted in fee-for-service settings during the 1970s, rather than managed care settings. In addition, the vast majority of PA and NP productivity studies have viewed PAs and NPs as physician substitutes rather than as members of interdisciplinary health care teams, which may become the dominant health care delivery model over the next 10-20 years.

  16. Arthritis-related work transitions: a prospective analysis of reported productivity losses, work changes, and leaving the labor force.

    Gignac, Monique A M; Cao, Xingshan; Lacaille, Diane; Anis, Aslam H; Badley, Elizabeth M

    2008-12-15

    To prospectively examine arthritis-related productivity losses, work changes, and leaving employment, the relationships among these work transitions, and the factors associated with them. Participants with inflammatory arthritis or osteoarthritis were interviewed at 4 time points, 18 months apart, using a structured questionnaire. At baseline (T1), all participants (n = 490; 381 women, 109 men) were employed. At T2, T3, and T4, the sample decreased to 413, 372, and 349 participants, respectively. Respondents were recruited using community advertising and from rheumatology and rehabilitation clinics. Work transitions considered were productivity losses (absenteeism, job disruptions), work changes (reduced hours, changing jobs), and leaving employment. Also measured were demographic, illness, work context, and psychological variables. Generalized estimation equations modeled predictors of work transitions over time. Although 63.1% of respondents remained employed throughout the study, work transitions were common (reported by 76.5% of participants). Productivity losses, especially job disruptions such as being unable to take on extra work, were the most frequently reported. Work transitions were related to subsequently making other work transitions, including leaving employment. Age, sex, education, activity limitations, control, depression, and arthritis-work spillover were also associated with work transitions. This study sheds light on a process of diverse employment changes that may occur in the lives of many individuals with arthritis. It emphasizes the interrelationships among work transitions, as well as other factors in predicting work transitions, and it provides insight into work changes that may signal impending difficulties with remaining employed.

  17. Limnology in El Dorado: some surprising aspects of the regulation of phytoplankton productive capacity in a high-altitude Andean lake (Laguna de Guatavita, Colombia

    Jhon Donato

    2012-09-01

    Full Text Available High-altitude mountain lakes remain understudied, mostly because of their relative inaccessibility. Laguna de Guatavita, a small, equatorial, high-altitude crater lake in the Eastern Range of the Colombian Andes, was once of high cultural importance to pre-Columban inhabitants, the original location of the legendary El Dorado. We investigated the factors regulating the primary production in Laguna de Guatavita (4°58’50” N - 73°46’43” W, alt. 2 935m.a.s.l., area: 0.11km², maximum depth: 30m, during a series of three intensive field campaigns, which were conducted over a year-long period in 2003-2004. In each, standard profiles of temperature, oxygen concentration and light intensity were determined on each of 16-18 consecutive days. Samples were collected and analysed for chlorophyll and for biologically-significant solutes in GF/F-filtered water (NH4+, NO3- , NO2-; soluble reactive phosphorus. Primary production was also determined, by oxygen generation, on each day of the campaign. Our results showed that the productive potential of the lake was typically modest (campaign averages of 45-90mg C/m².h but that many of the regulating factors were not those anticipated intuitively. The lake is demonstrably meromictic, reminiscent of karstic dolines in higher latitudes, its stratification being maintained by solute- concentration gradients. Light penetration is poor, attributable to the turbidity owing to fine calcite and other particulates in suspension. Net primary production in the mixolimnion of Laguna de Guavita is sensitive to day-to-day variations in solar irradiance at the surface. However, deficiencies in nutrient availability, especially nitrogen, also constrain the capacity of the lake to support a phytoplankton. We deduced that Laguna de Guatavita is something of a limnological enigma, atypical of the common anticipation of a “mountain lake”. While doubtlessly not unique, comparable descriptions of similar sites elsewhere

  18. Forced expression of stabilized c-Fos in dendritic cells reduces cytokine production and immune responses in vivo

    Yoshida, Ryoko; Suzuki, Mayu; Sakaguchi, Ryota; Hasegawa, Eiichi; Kimura, Akihiro; Shichita, Takashi; Sekiya, Takashi [Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo 160-8582 (Japan); Japan Science and Technology Agency, CREST, Chiyoda-ku 102-0075 (Japan); Shiraishi, Hiroshi [Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga (Japan); Shimoda, Kouji [Department of Laboratory Animal Center, Keio University School of Medicine, Tokyo (Japan); Yoshimura, Akihiko, E-mail: yoshimura@a6.keio.jp [Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo 160-8582 (Japan); Japan Science and Technology Agency, CREST, Chiyoda-ku 102-0075 (Japan)

    2012-06-29

    Highlights: Black-Right-Pointing-Pointer Dendritic cells expressing stabilized c-Fos produced less inflammatory cytokines. Black-Right-Pointing-Pointer Dendritic cells expressing stabilized c-Fos activated T cells less efficiently. Black-Right-Pointing-Pointer Transgenic mice expressing stabilized c-Fos were resistant to EAE model. -- Abstract: Intracellular cyclic adenosine monophosphate (cAMP) suppresses innate immunity by inhibiting proinflammatory cytokine production by monocytic cells. We have shown that the transcription factor c-Fos is responsible for cAMP-mediated suppression of inflammatory cytokine production, and that c-Fos protein is stabilized by IKK{beta}-mediated phosphorylation. We found that S308 is one of the major phosphorylation sites, and that the S308D mutation prolongs c-Fos halflife. To investigate the role of stabilized c-Fos protein in dendritic cells (DCs) in vivo, we generated CD11c-promoter-deriven c-FosS308D transgenic mice. As expected, bone marrow-derived DCs (BMDCs) from these Tg mice produced smaller amounts of inflammatory cytokines, including TNF-{alpha}, IL-12, and IL-23, but higher levels of IL-10, in response to LPS, than those from wild-type (Wt) mice. When T cells were co-cultured with BMDCs from Tg mice, production of Th1 and Th17 cytokines was reduced, although T cell proliferation was not affected. Tg mice demonstrated more resistance to experimental autoimmune encephalomyelitis (EAE) than did Wt mice. These data suggest that c-Fos in DCs plays a suppressive role in certain innate and adaptive immune responses.

  19. Work demands, job insecurity and sickness absence from work. how productive is the new, flexible labour force?

    D'Souza, Rennie M; Strazdins, Lyndall; Broom, Dorothy H; Rodgers, Bryan; Berry, Helen L

    2006-06-01

    We investigate one aspect of productivity--sickness absence--and ask whether job insecurity and high work demands are associated with increased sickness absence and, if so, whether mental or physical health mediates this association. We further investigate if having control at work modifies these associations. We used cross-sectional survey data from 2,248 employees aged 40-44 years living in two cities of south-eastern Australia. Logistic regressions were used to compare the associations between job insecurity and demands among those with short (1-3 days) or long-term (> 3 days) sickness absence with those who had no sickness absence in the last four weeks. The mediating effects of mental and physical health were assessed by evaluating changes in the magnitude of the association between these work conditions and sickness absence. High job insecurity (OR = 3.28; 95% CI 1.54-6.95) and high work demands (OR = 1.62; 95% CI 1.13-2.30) were significantly associated with long-term, but not with short-term, sickness absence. These associations were unaffected by job control. Depression and anxiety explained 61% of the association between high work demands and long-term sickness absence and 30% of the association between job insecurity and long-term sickness absence. Difficult working conditions may reduce productivity by contributing to longer absences from work. Reforms intended to improve economic performance should address any potential health costs of insecurity or intensification, which could inadvertently decrease productivity, possibly through their impact on mental health.

  20. Capacitated Dynamic Lot Sizing with Capacity Acquisition

    Li, Hongyan; Meissner, Joern

    One of the fundamental problems in operations management is to determine the optimal investment in capacity. Capacity investment consumes resources and the decision is often irreversible. Moreover, the available capacity level affects the action space for production and inventory planning decisions...

  1. A beginners guide for video production. [Prepared by the Energy Task Force of the Urban Consortium for Technology Initiatives

    1991-11-01

    The Seattle-King County Hazardous Waste Management Plan provides the framework for an intensive effort to keep Household Hazardous Waste (HHW) and Small Quantity Generator (SQG) wastes from entering the municipal solid and liquid waste streams. Many innovative programs for managing small sources of hazardous waste have been developed in response to the Plan. With the assistance of Urban Consortium grants, the City of Seattle has researched and developed a series of reports describing the planning, operation and evaluation of the plan's HHW collection programs. Three of the Plan's programs of particular interest to other jurisdictions are the fixed site and mobile HHW Collection Facilities, and the Business Waste Consultations provided to SQG's. In 1991, Seattle received an Urban Consortium grant to produce two videos showing how the HHW Collection Facilities and Business Consultations programs work. This report provides an overviews of the video development and production process and a discussion of the lessons learned by the staff directing the production.

  2. Labor Force

    Occupational Outlook Quarterly, 2012

    2012-01-01

    The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

  3. Implementing Estimation of Capacity for Freeway Sections

    Chang-qiao Shao

    2011-01-01

    Full Text Available Based on the stochastic concept for freeway capacity, the procedure of capacity estimation is developed. Due to the fact that it is impossible to observe the value of the capacity and to obtain the probability distribution of the capacity, the product-limit method is used in this paper to estimate the capacity. In order to implement estimation of capacity using this technology, the lifetime table based on statistical methods for lifetime data analysis is introduced and the corresponding procedure is developed. Simulated data based on freeway sections in Beijing, China, were analyzed and the results indicate that the methodology and procedure are applicable and validated.

  4. Investigation of forced and total degradation products of amlodipine besylate by liquid chromatography and liquid chromatography-mass spectrometry

    Stoiljković Zora Ž.

    2014-01-01

    Full Text Available An isocratic, reversed-phase liquid chromatographic method was applied for the investigation of the degradation products of amlodipine besylate under the stressed conditions in solution. Amlodipine besylate stock solutions were subjected to acid and alkali hydrolysis, chemical oxidation and photodegradation as well as to the electrochemical degradation by cyclic voltammetry in 0.05 mol/L NaHCO3 on gold electrode. The total degradation of amlodipine besylate was achieved in 5 mol/L NaOH at 80°C for 6 h and the compound with molecular formula C15H16NOCl was identified as a main degradation product. Under acidic (5 mol/L HCl at 80°C for 6 h stress conditions 75.2% of amlodipine besylate degradation was recorded. Oxidative degradation in the solution of 3% H2O2-methanol 80:20 at 80°C for 6 h showed that amlodipine besylate degraded to 80.1%. After 14 days of expose in photostability chamber amlodipine besylate solution showed degradation of 32.2%. In electrochemical degradation after 9 hours of cyclization the beginning of amlodipine oxidation was shifted for 200 mV to more negative potentials, with the degradation of 66.5%. Mass spectrometry analysis confirmed the presence of dehydro amlodipine derivate with molecular formula C20H23N2O5Cl in oxidative and acidic conditions while in electrochemical degradation was detected in traces. [Projekat Ministarsva nauke Republike Srbije, br. 172013

  5. Physical Forcing-Driven Productivity and Sediment Flux to the Deep Basin of Northern South China Sea: A Decadal Time Series Study

    Hon-Kit Lui

    2018-03-01

    Full Text Available Understanding the driving forces of absorption of anthropogenic CO2 by the oceans is critical for a sustainable ocean carbon cycle. Decadal sinking particle flux data collected at 1000 m, 2000 m, and 3500 m at the South East Asia Time Series Study (SEATS Station (18° N, 116° E, which was located in the northern South China Sea (nSCS, show that the fluxes undergo strong seasonal and interannual variability. Changes in the flux data are correlated with the satellite-derived chlorophyll-a concentration, indicating that the mass fluxes of the sinking particles are largely controlled by the export production at or near the SEATS station. The cooling of seawater and the strengthening of wind in winter increase the nutrient inventories in the euphotic zone, thus also increasing export production in the nSCS. This study reveals that the intrusion of low-nutrient seawater from the West Philippine Sea into the nSCS significantly reduces the productivity, and hence the flux, of sinking particles.

  6. Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: in vitro toxicity evaluation of major degradation products.

    Shankar, G; Borkar, R M; Suresh, U; Guntuku, L; Naidu, V G M; Nagesh, N; Srinivas, R

    2017-07-01

    Regulatory agencies from all over the world have set up stringent guidelines with regard to drug degradation products due to their toxic effects or carcinogenicity. Lansoprazole, a proton-pump inhibitor, was subjected to forced degradation studies as per ICH guidelines Q1A (R2). The drug was found to degrade under acidic, basic, neutral hydrolysis and oxidative stress conditions, whereas it was found to be stable under thermal and photolytic conditions. The chromatographic separation of the drug and its degradation products were achieved on a Hiber Purospher, C18 (250 × 4.6 mm, 5 μ) column using 10 mM ammonium acetate and acetonitrile as a mobile phase in a gradient elution mode at a flow rate of 1.0 ml/min. The eight degradation products (DP1-8) were identified and characterized by UPLC/ESI/HRMS with in-source CID experiments combined with accurate mass measurements. DP-1, DP-2 and DP-3 were formed in acidic, DP-4 in basic, DP-5 in neutral and DP-1, DP-6, DP-7 and DP-8 were in oxidation stress condition Among eight degradation products, five were hitherto unknown degradation products. In addition, one of the major degradation products, DP-2, was isolated by using semi preparative HPLC and other two, DP-6 and DP-7 were synthesized. The cytotoxic effect of these degradation products (DP-2, DP-6 and DP-7) were tested on normal human cells such as HEK 293 (embryonic kidney cells) and RWPE-1(normal prostate epithelial cells) by MTT assay. From the results of cytotoxicity, it was found that lansoprazole as well as its degradation products (DP-2, DP-6 and DP-7) were nontoxic up to 50-μM concentrations, and the latter showed slightly higher cytotoxicity when compared with that of lansoprazole. DNA binding studies using spectroscopic techniques indicate that DP-2, DP-6 and DP-7 molecules interact with ctDNA and may bind to its surface. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  7. Dispersion Forces

    Buhmann, Stefan Yoshi

    2012-01-01

    In this book, a modern unified theory of dispersion forces on atoms and bodies is presented which covers a broad range of advanced aspects and scenarios. Macroscopic quantum electrodynamics is shown to provide a powerful framework for dispersion forces which allows for discussing general properties like their non-additivity and the relation between microscopic and macroscopic interactions. It is demonstrated how the general results can be used to obtain dispersion forces on atoms in the presence of bodies of various shapes and materials. Starting with a brief recapitulation of volume I, this volume II deals especially with bodies of irregular shapes, universal scaling laws, dynamical forces on excited atoms, enhanced forces in cavity quantum electrodynamics, non-equilibrium forces in thermal environments and quantum friction. The book gives both the specialist and those new to the field a thorough overview over recent results in the field. It provides a toolbox for studying dispersion forces in various contex...

  8. Impaired growth and force production in skeletal muscles of young partially pancreatectomized rats: a model of adolescent type 1 diabetic myopathy?

    Carly S Gordon

    Full Text Available This present study investigated the temporal effects of type 1 diabetes mellitus (T1DM on adolescent skeletal muscle growth, morphology and contractile properties using a 90% partial pancreatecomy (Px model of the disease. Four week-old male Sprague-Dawley rats were randomly assigned to Px (n = 25 or Sham (n = 24 surgery groups and euthanized at 4 or 8 weeks following an in situ assessment of muscle force production. Compared to Shams, Px were hyperglycemic (>15 mM and displayed attenuated body mass gains by days 2 and 4, respectively (both P<0.05. Absolute maximal force production of the gastrocnemius plantaris soleus complex (GPS was 30% and 50% lower in Px vs. Shams at 4 and 8 weeks, respectively (P<0.01. GP mass was 35% lower in Px vs Shams at 4 weeks (1.24±0.06 g vs. 1.93±0.03 g, P<0.05 and 45% lower at 8 weeks (1.57±0.12 vs. 2.80±0.06, P<0.05. GP fiber area was 15-20% lower in Px vs. Shams at 4 weeks in all fiber types. At 8 weeks, GP type I and II fiber areas were ∼25% and 40% less, respectively, in Px vs. Shams (group by fiber type interactions, P<0.05. Phosphorylation states of 4E-BP1 and S6K1 following leucine gavage increased 2.0- and 3.5-fold, respectively, in Shams but not in Px. Px rats also had impaired rates of muscle protein synthesis in the basal state and in response to gavage. Taken together, these data indicate that exposure of growing skeletal muscle to uncontrolled T1DM significantly impairs muscle growth and function largely as a result of impaired protein synthesis in type II fibers.

  9. Capacity Ten-Seven

    NONE

    2006-05-04

    The study was initiated to assemble UK solar experts who would define the parameters for the design of solar cell process plant with a capacity of about 10MWp per annum and establish the optimum substrate size, cell configuration and junction structure and show that these characteristics are suited to high volume low cost production. The study focused on proven materials and techniques rather than on innovative materials and processes. Peak production should deliver panels at a cost of less than $1 per peak watt. The study was reported under the headings of fundamental studies, front contact deposition, semiconductor deposition, rear contact deposition, cell isolation and initial design study. Since much of the work is commercially sensitive, not all findings are divulged in the report. The work, which achieved all its targets, was carried out by ICP Solar Technologies UK Ltd under contract to the DTI.

  10. A Prospective, Multicenter Study to Compare a Disposable, High-fluid Capacity Underpad to Nonpermeable, Disposable, Reusable Containment Products on Incontinence-associated Dermatitis Rates Among Skilled Nursing Facility Residents.

    Motta, Glenda; Milne, Catherine T

    2017-12-01

    Due to the high prevalence of incontinence among skilled nursing facility (SNF) residents, incontinence-associated derma- titis (IAD) is a common occurrence. In addition, facility staff may mistakenly identify IAD as a pressure injury. A prospective, descriptive, multicenter study was conducted in 3 Connecticut facilities to evaluate the effect of substituting a disposable, high- uid capacity underpad for nonpermeable disposable and reusable containment products on the rate of IADs. Residents with and without IAD but with high IAD risk scores who were bed- or chairbound or ambulatory and used disposable nonpermeable briefs and underpads or reusable, laundered containment products when in bed longer than 2 hours were randomly enrolled and observed for a 4-week period. Facility staff were trained on the importance of differentiating between IAD and pressure injury; they substituted the study product (a disposable, high- uid capacity underpad) for all previously used containment products. Patient risk for IAD and skin condition were assessed using the Perineal Assessment Tool (PAT) and the Skin Condition Assessment Tool (SAT), respectively, at 5 time points: baseline, week 1, week 2, week 3, and week 4. The PAT is a 4-item instrument based conceptually on the 4 determinants in perineal skin breakdown; subscales are rated from 1 (least risk) to 3 (most risk), with a total score range of 4 to 12. The SAT is used to evaluate IAD speci cally, generating a cumulative severity score ranging from 0 to 3 on area of skin affected, degree of redness, and depth of ero- sion. Final data analysis was conducted on 40 residents: 25 had IAD present at enrollment and 15 were deemed high risk for developing IAD. Mean SAT scores in the 25 participants with IAD decreased with signi cance at week 1 (P = .0016), week 2 (P = .0023), week 3 (P = .0005), and week 4 (P disposable, high- uid capacity underpad improved SAT scores over time. IAD rates increased in each facility, but pressure

  11. Different forces

    1982-01-01

    The different forces, together with a pictorial analogy of how the exchange of particles works. The table lists the relative strength of the couplings, the quanta associated with the force fields and the bodies or phenomena in which they have a dominant role.

  12. Labor Force

    Occupational Outlook Quarterly, 2010

    2010-01-01

    The labor force is the number of people aged 16 or older who are either working or looking for work. It does not include active-duty military personnel or institutionalized people, such as prison inmates. Quantifying this total supply of labor is a way of determining how big the economy can get. Labor force participation rates vary significantly…

  13. Phytase-producing capacity of yeasts isolated from traditional African fermented food products and PHYPk gene expression of Pichia kudriavzevii strains

    Greppi, Anna; Krych, Lukasz; Costantini, Antonella

    2015-01-01

    Phytate is known as a strong chelate of minerals causing their reduced uptake by the human intestine. Ninety-three yeast isolates from traditional African fermented food products, belonging to nine species (Pichia kudriavzevii, Saccharomyces cerevisiae, Clavispora lusitaniae, Kluyveromyces...... marxianus, Millerozyma farinosa, Candida glabrata, Wickerhamomyces anomalus, Hanseniaspora guilliermondii and Debaryomyces nepalensis) were screened for phytase production on solid and liquid media. 95% were able to grow in the presence of phytate as sole phosphate source, P. kudriavzevii being the best...

  14. Outage capacity of multicarrier systems

    Yilmaz, Ferkan; Alouini, Mohamed-Slim

    2010-01-01

    The probability density function and the cumulative distribution function of the product of shifted Gamma variates are obtained in terms of the generalized Fox's H function. Using these new results, the exact outage capacity of multi carrier transmission through a slow Nakagami-m fading channel is presented. Moreover, it is shown that analytical and simulation results are in perfect agreement. © 2009 IEEE.

  15. Mammalian cell culture capacity for biopharmaceutical manufacturing.

    Ecker, Dawn M; Ransohoff, Thomas C

    2014-01-01

    : With worldwide sales of biopharmaceuticals increasing each year and continuing growth on the horizon, the manufacture of mammalian biopharmaceuticals has become a major global enterprise. We describe the current and future industry wide supply of manufacturing capacity with regard to capacity type, distribution, and geographic location. Bioreactor capacity and the use of single-use products for biomanufacturing are also profiled. An analysis of the use of this capacity is performed, including a discussion of current trends that will influence capacity growth, availability, and utilization in the coming years.

  16. Development of capacity for measuring ionizing radiation in aircraft crew; Desenvolvimento da capacitacao para efetuar medicoes de radiacao ionizante em tripulacoes de aeronaves

    Federico, C.A.; Goncalez, O.L., E-mail: claudiofederico@ieav.cta.b, E-mail: odairl@ieav.cta.b [Centro Tecnico Aeroespacial (CTA/ITA), Sao Jose dos Campos, SP (Brazil). Inst. Tecnologico de Aeronautica; Caldas, L.V.E., E-mail: lcaldas@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-10-26

    This paper describes the activities performed in a research program of the Institute of Advanced Studies, Brazil, belonging to the Brazilian Air Force, joining to researches from Brazilian Nuclear Energy Commission, in order to bring to Brazil the capacity and acknowledge necessary to the evaluation of dose from ionizing radiation originated in the cosmic radiation and its by products which fall on aircraft crews

  17. Abscisic Acid Induced Changes in Production of Primary and Secondary Metabolites, Photosynthetic Capacity, Antioxidant Capability, Antioxidant Enzymes and Lipoxygenase Inhibitory Activity of Orthosiphon stamineus Benth.

    Mohd Hafiz Ibrahim

    2013-07-01

    Full Text Available An experiment was conducted to investigate and distinguish the relationships in the production of total phenolics, total flavonoids, soluble sugars, H2O2, O2−, phenylalanine ammonia lyase (PAL activity, leaf gas exchange, antioxidant activity, antioxidant enzyme activity [ascorbate peroxidase (APX, catalase (CAT, superoxide dismutase (SOD and Lipoxygenase inhibitory activity (LOX] under four levels of foliar abscisic acid (ABA application (0, 2, 4, 6 µM for 15 weeks in Orthosiphon stamineus Benth. It was found that the production of plant secondary metabolites, soluble sugars, antioxidant activity, PAL activity and LOX inhibitory activity was influenced by foliar application of ABA. As the concentration of ABA was increased from 0 to 6 µM the production of total phenolics, flavonoids, sucrose, H2O2, O2−, PAL activity and LOX inhibitory activity was enhanced. It was also observed that the antioxidant capabilities (DPPH and ORAC were increased. This was followed by increases in production of antioxidant enzymes APX, CAT and SOD. Under high application rates of ABA the net photosynthesis and stomatal conductance was found to be reduced. The production of primary and secondary metabolites displayed a significant positive relationship with H2O2 (total phenolics, r2 = 0.877; total flavonoids, r2 = 0.812; p ≤ 0.05 and O2− (total phenolics, r2 = 0.778; total flavonoids, r2 = 0.912; p ≤ 0.05. This indicated that increased oxidative stress at high application rates of ABA, improved the production of phytochemicals.

  18. Comparative genomics and transcriptome analysis of Lactobacillus rhamnosus ATCC 11443 and the mutant strain SCT-10-10-60 with enhanced L-lactic acid production capacity.

    Sun, Liang; Lu, Zhilong; Li, Jianxiu; Sun, Feifei; Huang, Ribo

    2018-02-01

    Mechanisms for high L-lactic acid production remain unclear in many bacteria. Lactobacillus rhamnosus SCT-10-10-60 was previously obtained from L. rhamnosus ATCC 11443 via mutagenesis and showed improved L-lactic acid production. In this study, the genomes of strains SCT-10-10-60 and ATCC 11443 were sequenced. Both genomes are a circular chromosome, 2.99 Mb in length with a GC content of approximately 46.8%. Eight split genes were identified in strain SCT-10-10-60, including two LytR family transcriptional regulators, two Rex redox-sensing transcriptional repressors, and four ABC transporters. In total, 60 significantly up-regulated genes (log 2 fold-change ≥ 2) and 39 significantly down-regulated genes (log 2 fold-change ≤ - 2) were identified by a transcriptome comparison between strains SCT-10-10-60 and ATCC 11443. KEGG pathway enrichment analysis revealed that "pyruvate metabolism" was significantly different (P < 0.05) between the two strains. The split genes and the differentially expressed genes involved in the "pyruvate metabolism" pathway are probably responsible for the increased L-lactic acid production by SCT-10-10-60. The genome and transcriptome sequencing information and comparison of SCT-10-10-60 with ATCC 11443 provide insights into the anabolism of L-lactic acid and a reference for improving L-lactic acid production using genetic engineering.

  19. Analysis of india and Pakistan's nuclear capacity

    Li Zhimin

    1999-07-01

    The development and capacity of both India and Pakistan's nuclear weapons are described in production of weapon-grade materials, nuclear testing, weaponization engineering and delivery systems. India is capable of designing and manufacturing both small yield tactic nuclear weapons and big yield strategic ones and also possesses the technique to design and manufacture H-bombs. Weapon-grade plutonium constitutes the primary fission material for India's nuclear weapon and it has plutonium enough to make 70 to 100 nuclear weapons. India can also produce some tritium. India has already possessed delivery systems but it has not yet mounted nuclear warheads on its ballistic missiles even though its missiles, which India has already owned or is under development, have the ability to carry nuclear warheads. Pakistan also has the ability to make both tactic nuclear weapons and strategic ones. With its weapon-grade uranium, 20 to 30 nuclear weapons can be made. Besides the uranium production facility. Pakistan also has the facility to produce tritium. It is supposed that Pakistan has the ability to carry nuclear weapons with airplane, but it has a long way to go if it wants to mount nuclear weapon, especially bit yield ones, on its own missile. As a whole, India's nuclear force is stronger than Pakistan's, and its development far more advanced than Pakistan's

  20. Regional and monthly and clear-sky aerosol direct radiative effect (and forcing derived from the GlobAEROSOL-AATSR satellite aerosol product

    G. E. Thomas

    2013-01-01

    Full Text Available Using the GlobAEROSOL-AATSR dataset, estimates of the instantaneous, clear-sky, direct aerosol radiative effect and radiative forcing have been produced for the year 2006. Aerosol Robotic Network sun-photometer measurements have been used to characterise the random and systematic error in the GlobAEROSOL product for 22 regions covering the globe. Representative aerosol properties for each region were derived from the results of a wide range of literature sources and, along with the de-biased GlobAEROSOL AODs, were used to drive an offline version of the Met Office unified model radiation scheme. In addition to the mean AOD, best-estimate run of the radiation scheme, a range of additional calculations were done to propagate uncertainty estimates in the AOD, optical properties, surface albedo and errors due to the temporal and spatial averaging of the AOD fields. This analysis produced monthly, regional estimates of the clear-sky aerosol radiative effect and its uncertainty, which were combined to produce annual, global mean values of (−6.7 ± 3.9 W m−2 at the top of atmosphere (TOA and (−12 ± 6 W m−2 at the surface. These results were then used to give estimates of regional, clear-sky aerosol direct radiative forcing, using modelled pre-industrial AOD fields for the year 1750 calculated for the AEROCOM PRE experiment. However, as it was not possible to quantify the uncertainty in the pre-industrial aerosol loading, these figures can only be taken as indicative and their uncertainties as lower bounds on the likely errors. Although the uncertainty on aerosol radiative effect presented here is considerably larger than most previous estimates, the explicit inclusion of the major sources of error in the calculations suggest that they are closer to the true constraint on this figure from similar methodologies, and point to the need for more, improved estimates of both global aerosol loading and aerosol optical properties.

  1. Determination of optimum production capacity and mine life considering net present value in open pit mining at different overall slope angles

    Tahir Malli; Cagatay Pamukcu; Halil Köse

    2015-01-01

    In modern mining industry, with increasing competitive environment and unit costs, it is necessary to evaluate mineral resources optimally from the aspects of economy, safety and environment. On the other hand, production increase is another reality and obligation for today’s mining operations. The activities related to the extraction of ore deposit consist of risky operations, which are a great hazard for capital investments that will take many years. Therefore, in terms of feasibil...

  2. Decision project related to the energy multi-year 2018/2023 planning (PPE). Evolution of capacities of production of power generating renewable energies: the headlong rush

    Perves, Jean-Pierre

    2016-01-01

    After having recalled that the French government, in its energy multi-year planning for 2018-2023, decided to develop wind and photovoltaic energies at a higher rate, despite their intermittency and the need for back-up nuclear and hydroelectric power plants (which do not emit carbon), and outlined that the power market is now in the torment, in France and in Europe, the author notices that such a development of renewable energies is a matter of concern in Europe, and indicates the objectives defined by the French government for onshore and offshore wind energy and for solar energy. Then, he proposes a critical analysis of the low level scenario of this development, a scenario which the author assesses as not very realistic. A table indicates the status and objectives for all the different renewable energies. The author discusses these values, notices that it is similar to a programme defined by the ADEME. He analyses the 2018/2023 low scenario (production, share, production efficiency, minimum and maximum power) by comparing it with the situation in 2015. He outlines important seasonal variations for wind and solar energy: their production level in winter requires a massive use of other sources. He briefly discusses the perspectives for 2030, and then addresses the development cost in terms of required investments. He discusses the impact of the scenario on greenhouse gas emissions. The appendix provides the official text of the decision project

  3. Total iron binding capacity

    ... page: //medlineplus.gov/ency/article/003489.htm Total iron binding capacity To use the sharing features on this page, please enable JavaScript. Total iron binding capacity (TIBC) is a blood test to ...

  4. Air capacity for Sydney

    Forsyth, Peter

    2013-01-01

    Like most large cities, Sydney has an airport problem. Demand is increasing faster than supply, and additional capacity will be needed if costly rationing, and delays, are to be avoided. However, compared to many cities, the problems facing Sydney are modest. At the moment, demand is only just exceeding capacity. There is a good chance that the available capacity will be rationed efficiently. Options for expanding capacity are being evaluated well. There may be problems in the future- poor op...

  5. Responsibility and Capacities

    Ryberg, Jesper

    2014-01-01

    That responsible moral agency presupposes certain mental capacities, constitutes a widely accepted view among theorists. Moreover, it is often assumed that degrees in the development of the relevant capacities co-vary with degrees of responsibility. In this article it is argued that, the move from...... the view that responsibility requires certain mental capacities to the position that degrees of responsibility co-vary with degrees of the development of the mental capacities, is premature....

  6. EMG and force production of the flexor hallucis longus muscle in isometric plantarflexion and the push-off phase of walking.

    Péter, Annamária; Hegyi, András; Stenroth, Lauri; Finni, Taija; Cronin, Neil J

    2015-09-18

    Large forces are generated under the big toe in the push-off phase of walking. The largest flexor muscle of the big toe is the flexor hallucis longus (FHL), which likely contributes substantially to these forces. This study examined FHL function at different levels of isometric plantarflexion torque and in the push-off phase at different speeds of walking. FHL and calf muscle activity were measured with surface EMG and plantar pressure was recorded with pressure insoles. FHL activity was compared to the activity of the calf muscles. Force and impulse values were calculated under the big toe, and were compared to the entire pressed area of the insole to determine the relative contribution of big toe flexion forces to the ground reaction force. FHL activity increased with increasing plantarflexion torque level (F=2.8, P=0.024) and with increasing walking speed (F=11.608, Ppush-off phase of walking, peak force under the big toe increased at a higher rate than force under the other areas of the plantar surface (F=3.801, P=0.018), implying a greater relative contribution to total force at faster speeds. Moreover, substantial differences were found between isometric plantarflexion and walking concerning FHL activity relative to that of the calf muscles, highlighting the task-dependant behaviour of FHL. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. CDMA systems capacity engineering

    Kim, Kiseon

    2004-01-01

    This new hands-on resource tackles capacity planning and engineering issues that are crucial to optimizing wireless communication systems performance. Going beyond the system physical level and investigating CDMA system capacity at the service level, this volume is the single-source for engineering and analyzing systems capacity and resources.

  8. PAYMENT CAPACITY SENSITIVITY FACTORS

    Daniel BRÎNDESCU – OLARIU

    2014-11-01

    The results of the study facilitate the determination and classification of the main sensitivity factors for the payment capacity at sample level, the establishment of general benchmarks for the payment capacity (as no such benchmarks currently exist in the Romanian literature and the identification of the mechanisms through which the variation of different factors impacts the payment capacity.

  9. Theoretical innovation and technical progress will usher in a production period of gas fields with an annual capacity of ten billion cubic meters

    Zhenwei Gan

    2017-01-01

    Full Text Available Challenged by the increasing complexity of targets and the tense situation of turning losses into profits during the 12th Five-Year Plan, by virtue of technological innovation, Sinopec Southwest Oil & Gas Company proposed the theories of gas exploration in continental clastic rock and marine carbonate rock, and developed the development technologies for reef, channel sandstone and tight sandstone reservoirs. Moreover, it innovatively formed a series of engineering technologies, including intelligent sliding sleeve staged fracturing, blasting–packing–fracturing stimulation, impulse fracturing, and drilling, completion and production technologies for ultra-deep horizontal wells with high sulfur contents. With these innovated theories and improved technologies, great discoveries have been made in the continental clastic rocks and marine carbonate rocks in West Sichuan Basin, the marine shale in South Sichuan Basin, and the marine carbonate rocks in Yuanba area of NE Sichuan Basin, and three 100 billion-m3 class commercial gas reserves zones were discovered. Moreover, two medium- and large-sized gas fields were proved, and three medium- and large-sized gas fields were completely constructed. Both reserves and production reached a new record in history. During the 13th Five-Year Plan, Sinopec Southwest Oil & Gas Company will focus on the exploration and development of deep marine carbonate reservoirs, commercial development of deep shale gas, safe development of gas fields with high sulfur, and enhancement of recovery in mature gas fields. By the end of the 13th Five-Year Plan, it is expected that the annual gas production of (10–12 × 109 m3 will be achieved.

  10. [Methodological aspects of evaluation of potential lipid capacity for peroxidation from the serum levels of TBA-active products during iron ion stimulation].

    Kulikova, A I; Tugusheva, F A; Zubina, I M; Shepilova, I N

    2008-05-01

    The authors propose a simple and reproducible procedure for using iron ions to stimulate serum lipid peroxidation, with TBA-active products being further determined. The procedure determines the reserve of lipids that can be oxidized during oxidative stress. A combination of direct studies and correlation analysis suggests that low-density lipoproteins and very low-density lipoproteins are the major substrates for lipid peroxidation while high-density lipoproteins show a high resistance to this process. The presented procedure may be used to monitor lipid peroxidation in various conditions and upon various exposures in common laboratory practice.

  11. Phytase-producing capacity of yeasts isolated from traditional African fermented food products and PHYPk gene expression of Pichia kudriavzevii strains.

    Greppi, Anna; Krych, Łukasz; Costantini, Antonella; Rantsiou, Kalliopi; Hounhouigan, D Joseph; Arneborg, Nils; Cocolin, Luca; Jespersen, Lene

    2015-07-16

    Phytate is known as a strong chelate of minerals causing their reduced uptake by the human intestine. Ninety-three yeast isolates from traditional African fermented food products, belonging to nine species (Pichia kudriavzevii, Saccharomyces cerevisiae, Clavispora lusitaniae, Kluyveromyces marxianus, Millerozyma farinosa, Candida glabrata, Wickerhamomyces anomalus, Hanseniaspora guilliermondii and Debaryomyces nepalensis) were screened for phytase production on solid and liquid media. 95% were able to grow in the presence of phytate as sole phosphate source, P. kudriavzevii being the best growing species. A phytase coding gene of P. kudriavzevii (PHYPk) was identified and its expression was studied during growth by RT-qPCR. The expression level of PHYPk was significantly higher in phytate-medium, compared to phosphate-medium. In phytate-medium expression was seen in the lag phase. Significant differences in gene expression were detected among the strains as well as between the media. A correlation was found between the PHYPk expression and phytase extracellular activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Cultivating Institutional Capacities for Learning Analytics

    Lonn, Steven; McKay, Timothy A.; Teasley, Stephanie D.

    2017-01-01

    This chapter details the process the University of Michigan developed to build institutional capacity for learning analytics. A symposium series, faculty task force, fellows program, research grants, and other initiatives are discussed, with lessons learned for future efforts and how other institutions might adapt such efforts to spur cultural…

  13. TAO2000 V2 computer-assisted force feedback tele-manipulators used as maintenance and production tools at the AREVA NC-La Hague fuel recycling plant

    Geffard, Franck; Garrec, Philippe; Piolain, Gerard; Brudieu, Marie-Anne; Thro, Jean-Francois; Coudray, Alain; Lelann, Eric

    2012-01-01

    During a 15-year joint research program, French Atomic Energy Agency Interactive Robotics Laboratory (CEA LIST) and AREVA have developed several remote operation devices, also called tele-robots. Some of them are now commonly used for maintenance operations at the AREVA NC (Nuclear Cycle) La Hague reprocessing plant. Since the first maintenance operation in 2005, several other successful interventions have been realized using the industrial MA23/RX170 tele-manipulation system. Moreover, since 2010, the through-the-wall tele-robot named MT200 TAO based on the slave arm of the MSM MT200 (La Calhene TM ), has been evaluated in an active production cell at the AREVA NC La Hague fuel recycling plant. Although these evaluations are ongoing, the positive results obtained have led to an update and industrialization program. All these developments are based on the same generic control platform, called TAO2000 V2. TAO2000 V2 is the second release of the CEA LIST core software platform dedicated to computer aided force-feedback tele-operation (TAO is the French acronym for computer aided tele-operation). This paper presents all these developments resulting from the joint research program CEA LIST/AREVA. The TAO2000 V2 controller is first detailed, and then two maintenance operations using the industrial robot RX170 are presented: the removal of the nuclear fuel dissolver wheel rollers and the cleanup of the dissolver wheel inter-bucket spaces. Finally, the new MT200 TAO system and its evaluations at the AREVA NC La Hague facilities are discussed. (authors)

  14. Nuclear forces

    Holinde, K.

    1990-01-01

    In this paper the present status of the meson theory of nuclear forces is reviewed. After some introductory remarks about the relevance of the meson exchange concept in the era of QCD and the empirical features of the NN interaction, the exciting history of nuclear forces is briefly outlined. In the main part, the author gives the basic physical ideas and sketch the derivation of the one-boson-exchange model of the nuclear force, in the Feynman approach. Secondly we describe, in a qualitative way, various necessary extensions, leading to the Bonn model of the N interaction. Finally, points to some interesting pen questions connected with the extended quark structure of the hadrons, which are topics of current research activity

  15. Inventory management with advance capacity information

    Jaksic, M.; Fransoo, J.C.; Tan, T.; Kok, de A.G.; Rusjan, B.

    2008-01-01

    One of the important aspects of supply chain management is dealing with demand and supply uncertainty. The uncertainty of future supply can be reduced, if a company is able to obtain advance capacity information (ACI) on future supply/production capacity availability from its supplier. We address a

  16. Inventory management with advance capacity information

    Jaksic, M.; Fransoo, J.C.; Tan, T.; Kok, de A.G.; Rusjan, B.

    2011-01-01

    An important aspect of supply chain management is dealing with demand and supply uncertainty. The uncertainty of future supply can be reduced if a company is able to obtain advance capacity information (ACI) about future supply/production capacity availability from its supplier. We address a

  17. Capacity building for sustainable energy development

    Rogner, Hans-Holger

    2006-01-01

    Capacity Building for Sustainable Energy Development - Mission: To build capacity in Member States (MS) for comprehensive energy system, economic and environmental analyses to assist in: - making informed policy decisions for sustainable energy development; - assessing the role of nuclear power; - understanding environmental and climate change issues related to energy production and use

  18. Effect of treatment with natalizumab on ability to work in people with multiple sclerosis: productivity gain based on direct measurement of work capacity before and after 1 year of treatment.

    Olofsson, Sara; Wickström, Anne; Häger Glenngård, Anna; Persson, Ulf; Svenningsson, Anders

    2011-10-01

    Sweden is a high endemic region for multiple sclerosis (MS), a neurologic disorder characterized by repeated inflammatory episodes affecting the CNS. The disease has its peak age of onset at approximately 30 years and affects women twice as often as men. The young age of onset makes MS one of the major causes of reduced capacity to work due to neurologic disease in Western society. Natalizumab (Tysabri®) is among the new generation of biologic drugs for the treatment of MS. Clinical studies have demonstrated that natalizumab is an effective treatment for preventing relapses and inflammatory activity. The aim of the study was to estimate the monetary value of treatment with natalizumab on the ability to work in patients with MS in Sweden, based on a direct measurement of weekly hours worked before and after 1 year of treatment with natalizumab. A sample of patients, consisting of all patients who had started treatment with natalizumab during the period June 2007-May 2008, was identified through the Swedish Multiple Sclerosis Register (SMSreg). Data about sex, age, disease severity, and disease duration were collected from the register. Data about type of work and work capacity (number of hours worked per week) were collected retrospectively through a postal questionnaire. The average hours worked per week was estimated at baseline (2 weeks before treatment started) and at follow-up (50 weeks after treatment started), and the change was assigned an economic value using the human capital approach. This study showed that after 50 weeks of treatment with natalizumab, people with MS increased their productivity by 3.3 hours per week on average (p productivity gain (p = 0.025 and p = 0.002, respectively). A shorter duration of illness and a lower age at the start of treatment were significantly associated with a greater productivity gain after 50 weeks of treatment with natalizumab, which indicates that it is more beneficial to initiate efficient therapy early

  19. Low cost solar array project silicon materials task. Development of a process for high capacity arc heater production of silicon for solar arrays

    Fey, M. G.

    1981-01-01

    The experimental verification system for the production of silicon via the arc heater-sodium reduction of SiCl4 was designed, fabricated, installed, and operated. Each of the attendant subsystems was checked out and operated to insure performance requirements. These subsystems included: the arc heaters/reactor, cooling water system, gas system, power system, Control & Instrumentation system, Na injection system, SiCl4 injection system, effluent disposal system and gas burnoff system. Prior to introducing the reactants (Na and SiCl4) to the arc heater/reactor, a series of gas only-power tests was conducted to establish the operating parameters of the three arc heaters of the system. Following the successful completion of the gas only-power tests and the readiness tests of the sodium and SiCl4 injection systems, a shakedown test of the complete experimental verification system was conducted.

  20. Analysis of Cell Signal Transduction Based on Kullback–Leibler Divergence: Channel Capacity and Conservation of Its Production Rate during Cascade

    Tatsuaki Tsuruyama

    2018-06-01

    Full Text Available Kullback–Leibler divergence (KLD is a type of extended mutual entropy, which is used as a measure of information gain when transferring from a prior distribution to a posterior distribution. In this study, KLD is applied to the thermodynamic analysis of cell signal transduction cascade and serves an alternative to mutual entropy. When KLD is minimized, the divergence is given by the ratio of the prior selection probability of the signaling molecule to the posterior selection probability. Moreover, the information gain during the entire channel is shown to be adequately described by average KLD production rate. Thus, this approach provides a framework for the quantitative analysis of signal transduction. Moreover, the proposed approach can identify an effective cascade for a signaling network.

  1. Simulations of floor cooling system capacity

    Odyjas, Andrzej; Górka, Andrzej

    2013-01-01

    Floor cooling system capacity depends on its physical and operative parameters. Using numerical simulations, it appears that cooling capacity of the system largely depends on the type of cooling loads occurring in the room. In the case of convective cooling loads capacity of the system is small. However, when radiation flux falls directly on the floor the system significantly increases productivity. The article describes the results of numerical simulations which allow to determine system capacity in steady thermal conditions, depending on the type of physical parameters of the system and the type of cooling load occurring in the room. Moreover, the paper sets out the limits of system capacity while maintaining a minimum temperature of the floor surface equal to 20 °C. The results are helpful for designing system capacity in different type of cooling loads and show maximum system capacity in acceptable thermal comfort condition. -- Highlights: ► We have developed numerical model for simulation of floor cooling system. ► We have described floor system capacity depending on its physical parameters. ► We have described floor system capacity depending on type of cooling loads. ► The most important in the obtained cooling capacities is the type of cooling loads. ► The paper sets out the possible maximum cooling floor system capacity

  2. Crop water productivity under increasing irrigation capacities in Romania. A spatially-explicit assessment of winter wheat and maize cropping systems in the southern lowlands of the country

    Dogaru, Diana

    2016-04-01

    Improved water use efficiency in agriculture is a key issue in terms of sustainable management and consumption of water resources in the context of peoples' increasing food demands and preferences, economic growth and agricultural adaptation options to climate variability and change. Crop Water Productivity (CWP), defined as the ratio of yield (or value of harvested crop) to actual evapotranspiration or as the ratio of yield (or value of harvested crop) to volume of supplied irrigation water (Molden et al., 1998), is a useful indicator in the evaluation of water use efficiency and ultimately of cropland management, particularly in the case of regions affected by or prone to drought and where irrigation application is essential for achieving expected productions. The present study investigates the productivity of water in winter wheat and maize cropping systems in the Romanian Plain (49 594 sq. km), an important agricultural region in the southern part of the country which is increasingly affected by drought and dry spells (Sandu and Mateescu, 2014). The scope of the analysis is to assess the gains and losses in CWP for the two crops, by considering increased irrigated cropland and improved fertilization, these being the most common measures potentially and already implemented by the farmers. In order to capture the effects of such measures on agricultural water use, the GIS-based EPIC crop-growth model (GEPIC) (Williams et al., 1989; Liu, 2009) was employed to simulate yields, seasonal evapotranspiration from crops and volume of irrigation water in the Romanian Plain for the 2002 - 2013 interval with focus on 2007 and 2010, two representative years for dry and wet periods, respectively. The GEPIC model operates on a daily time step, while the geospatial input datasets for this analysis (e.g. climate data, soil classes and soil parameters, land use) were harmonized at 1km resolution grid cell. The sources of the spatial data are mainly the national profile agencies

  3. Surface forces studied with colloidal probe atomic force microscopy

    Giesbers, M.

    2001-01-01

    Forces between surfaces are a determining factor for the performance of natural as well as synthetic colloidal systems, and play a crucial role in industrial production processes. Measuring these forces is a scientific and experimental challenge and over the years several techniques have

  4. Agricultural net primary production in relation to that liberated by the extinction of Pleistocene mega-herbivores: an estimate of agricultural carrying capacity?

    Doughty, Christopher E; Field, Christopher B, E-mail: chris.doughty@ouce.ox.ac.uk, E-mail: cfield@ciw.edu [Department of Global Ecology, Carnegie Institution, Stanford, CA 94305 (United States)

    2010-10-15

    Mega-fauna (defined as animals > 44 kg) experienced a global extinction with 97 of 150 genera going extinct by {approx} 10 000 years ago. We estimate the net primary production (NPP) that was liberated following the global extinction of these mega-herbivores. We then explore how humans, through agriculture, gradually appropriated this liberated NPP, with specific calculations for 800, 1850, and 2000 AD. By 1850, most of the liberated NPP had been appropriated by people, but NPP was still available in the Western US, South America and Australia. NPP liberated following the extinction of the mega-herbivores was {approx} 2.5% ({approx}1.4 (between 1.2 and 1.6) Pg yr{sup -1} of 56 Pg C yr{sup -1}; Pg: petagrams) of global terrestrial NPP. Liberated NPP peaked during the onset of agriculture and was sufficient for sustaining human agriculture until {approx} 320 (250-500) years ago. Humans currently use {approx} 6 times more NPP than was utilized by the extinct Pleistocene mega-herbivores.

  5. Agricultural net primary production in relation to that liberated by the extinction of Pleistocene mega-herbivores: an estimate of agricultural carrying capacity?

    Doughty, Christopher E; Field, Christopher B

    2010-01-01

    Mega-fauna (defined as animals > 44 kg) experienced a global extinction with 97 of 150 genera going extinct by ∼ 10 000 years ago. We estimate the net primary production (NPP) that was liberated following the global extinction of these mega-herbivores. We then explore how humans, through agriculture, gradually appropriated this liberated NPP, with specific calculations for 800, 1850, and 2000 AD. By 1850, most of the liberated NPP had been appropriated by people, but NPP was still available in the Western US, South America and Australia. NPP liberated following the extinction of the mega-herbivores was ∼ 2.5% (∼1.4 (between 1.2 and 1.6) Pg yr -1 of 56 Pg C yr -1 ; Pg: petagrams) of global terrestrial NPP. Liberated NPP peaked during the onset of agriculture and was sufficient for sustaining human agriculture until ∼ 320 (250-500) years ago. Humans currently use ∼ 6 times more NPP than was utilized by the extinct Pleistocene mega-herbivores.

  6. Impacts of 2°C global warming on primary production and soil carbon storage capacity at pan-European level

    Abdulla Sakalli

    2017-08-01

    Full Text Available Atmospheric CO2 has been dramatically increasing since beginning of the industrial time (i.e. 1860, being one of the main driver for climate change at regional and global level. The change in CO2 concentration in the atmosphere, together with that of temperature, precipitation and/or so radiation, can influence the biogeochemical cycles in all ecosystems. In this study, we investigate the combined effect of CO2 concentration and six climate variables on carbon uptake, i.e., gross primary production (GPP and carbon storage, i.e, soil carbon (SoilC in terrestrial biosphere by using the Community Land Model (CLM vers. 4.5 and evaluate the model’s results against available observation data. We also analysed the change in carbon uptake and storage under a 2°C global mean warming. Results show that the model performed reasonably well for GPP and SoilC at pan-European scale. We also found a positive correlation between GPP, precipitation and surface wind, and a negative correlation between GPP and surface downwelling longwave radiation (rlds. Under a 2°C global warming, GPP and SoilC show an increase, an average, of about 20%, and 5% at pan-European scale, respectively. However, our results indicate that CLM4.5 may need improvements particularly in carbon-nitrogen interaction and carbon accumulation in soil.

  7. Outage capacity of multicarrier systems

    Yilmaz, Ferkan

    2010-01-01

    The probability density function and the cumulative distribution function of the product of shifted Gamma variates are obtained in terms of the generalized Fox\\'s H function. Using these new results, the exact outage capacity of multi carrier transmission through a slow Nakagami-m fading channel is presented. Moreover, it is shown that analytical and simulation results are in perfect agreement. © 2009 IEEE.

  8. Control system for forced-air cooling of horticultural products Sistema de controle para o resfriamento com ar forçado de produtos hortícolas

    João C. T. R. da Silva

    2011-01-01

    Full Text Available This work is a study of the implementation of a classical controller using a tuning method referred to as IMC (Internal Model Control and aimed at the reduction of electrical energy consumption by the appropriate relation between energy consumption and the cooling time with forced air. The supervisory system installed was able to manipulate the variable of frequency of the signal power of the exhaust fan engine (forced air module, to accelerate or decelerate the loss of heat from the product to be cooled by airflow variation that passes through the mass of the produce. The results demonstrated a reduction in energy consumption from 64% and an increase of only 8% in the cooling time to the system using PI/IMC (Proportional - Integral with IMC tuning method compared with the system in its operating nominal condition. This PI/IMC control may be implemented directly in a frequency converter, without the need to purchase a computer or PLC (programmable logic controller to run the dedicated application, increasing its economical viability.Este trabalho consiste no estudo da implementação de um controlador clássico utilizando o método de sintonia denominado por Controle de Modelo Interno, visando à redução do consumo de energia elétrica que decorra na adequada relação entre este consumo e o tempo de resfriamento do processo de resfriamento com ar forçado de produtos hortícolas. Para isto, o sistema supervisório instalado manipulou a variável de frequência do sinal de alimentação do motor de indução trifásico do exaustor (módulo de ar forçado, para acelerar ou desacelerar a perda de calor do produto a ser resfriado por intermédio da variação da vazão de ar que perpassava a massa deste produto. Obteve-se como resultado uma redução no consumo de energia elétrica de 64% e um acréscimo de apenas 8% no tempo de resfriamento para o sistema utilizando um controle proporcional e integral associado ao método de sintonia promovido

  9. Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes

    Yu, Y; Hanssen, KF; Kalyanaraman, V; Chirindel, A; Jenkins, AJ; Nankervis, AJ; Torjesen, PA; Scholz, H; Henriksen, T; Lorentzen, B; Garg, SK; Menard, MK; Hammad, SM; Scardo, JA; Stanley, JR; Wu, M; Basu, A; Aston, CE; Lyons, TJ

    2014-01-01

    Objective Increased advanced glycation end-products (AGEs) and their soluble receptors (sRAGE) have been implicated in the pathogenesis of pre-eclampsia (PE). However, this association has not been elucidated in pregnancies complicated by diabetes. We aimed to investigate the serum levels of these factors in pregnant women with Type 1 diabetes mellitus (T1DM), a condition associated with a four-fold increase in PE. Design Prospective study in women with T1DM at 12.2 ± 1.9, 21.6 ± 1.5 and 31.5 ± 1.7 weeks of gestation [mean ± standard deviation (SD); no overlap] before PE onset. Setting Antenatal clinics. Population Pregnant women with T1DM (n = 118; 26 developed PE) and healthy nondiabetic pregnant controls (n = 21). Methods Maternal serum levels of sRAGE (total circulating pool), Nε-(carboxymethyl)lysine (CML), hydroimidazolone (methylglyoxal-modified proteins) and total AGEs were measured by immunoassays. Main outcome measures Serum sRAGE and AGEs in pregnant women with T1DM who subsequently developed PE (DM PE+) versus those who remained normotensive (DM PE–). Results In DM PE+ versus DM PE–, sRAGE was significantly lower in the first and second trimesters, prior to the clinical manifestation of PE (P diabetes, parity and mean arterial pressure as covariates. Conclusions In the early stages of pregnancy, lower circulating sRAGE levels, and the ratio of sRAGE to AGEs, may be associated with the subsequent development of PE in women with T1DM. PMID:22900949

  10. Pullout capacity of batter pile in sand.

    Nazir, Ashraf; Nasr, Ahmed

    2013-03-01

    Many offshore structures are subjected to overturning moments due to wind load, wave pressure, and ship impacts. Also most of retaining walls are subjected to horizontal forces and bending moments, these forces are due to earth pressure. For foundations in such structures, usually a combination of vertical and batter piles is used. Little information is available in the literature about estimating the capacity of piles under uplift. In cases where these supporting piles are not vertical, the behavior under axial pullout is not well established. In order to delineate the significant variables affecting the ultimate uplift shaft resistance of batter pile in dry sand, a testing program comprising 62 pullout tests was conducted. The tests are conducted on model steel pile installed in loose, medium, and dense sand to an embedded depth ratio, L/d, vary from 7.5 to 30 and with various batter angles of 0°, 10°, 20°, and 30°. Results indicate that the pullout capacity of a batter pile constructed in dense and/or medium density sand increases with the increase of batter angle attains maximum value and then decreases, the maximum value of Pα occurs at batter angle approximately equal to 20°, and it is about 21-31% more than the vertical pile capacity, while the pullout capacity for batter pile that constructed in loose sand decreases with the increase of pile inclination. The results also indicated that the circular pile is more resistant to pullout forces than the square and rectangular pile shape. The rough model piles tested is experienced 18-75% increase in capacity compared with the smooth model piles. The suggested relations for the pullout capacity of batter pile regarding the vertical pile capacity are well predicted.

  11. Pullout capacity of batter pile in sand

    Ashraf Nazir

    2013-03-01

    Full Text Available Many offshore structures are subjected to overturning moments due to wind load, wave pressure, and ship impacts. Also most of retaining walls are subjected to horizontal forces and bending moments, these forces are due to earth pressure. For foundations in such structures, usually a combination of vertical and batter piles is used. Little information is available in the literature about estimating the capacity of piles under uplift. In cases where these supporting piles are not vertical, the behavior under axial pullout is not well established. In order to delineate the significant variables affecting the ultimate uplift shaft resistance of batter pile in dry sand, a testing program comprising 62 pullout tests was conducted. The tests are conducted on model steel pile installed in loose, medium, and dense sand to an embedded depth ratio, L/d, vary from 7.5 to 30 and with various batter angles of 0°, 10°, 20°, and 30°. Results indicate that the pullout capacity of a batter pile constructed in dense and/or medium density sand increases with the increase of batter angle attains maximum value and then decreases, the maximum value of Pα occurs at batter angle approximately equal to 20°, and it is about 21–31% more than the vertical pile capacity, while the pullout capacity for batter pile that constructed in loose sand decreases with the increase of pile inclination. The results also indicated that the circular pile is more resistant to pullout forces than the square and rectangular pile shape. The rough model piles tested is experienced 18–75% increase in capacity compared with the smooth model piles. The suggested relations for the pullout capacity of batter pile regarding the vertical pile capacity are well predicted.

  12. Heritability of polyphenols, anthocyanins and antioxidant capacity of ...

    ALL

    They can increase the antioxidant capacity ... cytokines, while increasing the production of anti- inflammatory ...... Evaluation of bitterness and astringency of ... phytochemicals and a higher antioxidant capacity than teas and red wine. J. Agric.

  13. One size does not fit all: a qualitative content analysis of the importance of existing quality improvement capacity in the implementation of Releasing Time to Care: the Productive Ward™ in Saskatchewan, Canada.

    Hamilton, Jessica; Verrall, Tanya; Maben, Jill; Griffiths, Peter; Avis, Kyla; Baker, G Ross; Teare, Gary

    2014-12-19

    Releasing Time to Care: The Productive Ward™ (RTC) is a method for conducting continuous quality improvement (QI). The Saskatchewan Ministry of Health mandated its implementation in Saskatchewan, Canada between 2008 and 2012. Subsequently, a research team was developed to evaluate its impact on the nursing unit environment. We sought to explore the influence of the unit's existing QI capacity on their ability to engage with RTC as a program for continuous QI. We conducted interviews with staff from 8 nursing units and asked them to speak about their experience doing RTC. Using qualitative content analysis, and guided by the Organizing for Quality framework, we describe the existing QI capacity and impact of RTC on the unit environment. The results focus on 2 units chosen to highlight extreme variation in existing QI capacity. Unit B was characterized by a strong existing environment. RTC was implemented in an environment with a motivated manager and collaborative culture. Aided by the structural support provided by the organization, the QI capacity on this unit was strengthened through RTC. Staff recognized the potential of using the RTC processes to support QI work. Staff on unit E did not have the same experience with RTC. Like unit B, they had similar structural supports provided by their organization but they did not have the same existing cultural or political environment to facilitate the implementation of RTC. They did not have internal motivation and felt they were only doing RTC because they had to. Though they had some success with RTC activities, the staff did not have the same understanding of the methods that RTC could provide for continuous QI work. RTC has the potential to be a strong tool for engaging units to do QI. This occurs best when RTC is implemented in a supporting environment. One size does not fit all and administrative bodies must consider the unique context of each environment prior to implementing large-scale QI projects. Use of an

  14. Emergent biosynthetic capacity in simple microbial communities.

    Hsuan-Chao Chiu

    2014-07-01

    Full Text Available Microbes have an astonishing capacity to transform their environments. Yet, the metabolic capacity of a single species is limited and the vast majority of microorganisms form complex communities and join forces to exhibit capabilities far exceeding those achieved by any single species. Such enhanced metabolic capacities represent a promising route to many medical, environmental, and industrial applications and call for the development of a predictive, systems-level understanding of synergistic microbial capacity. Here we present a comprehensive computational framework, integrating high-quality metabolic models of multiple species, temporal dynamics, and flux variability analysis, to study the metabolic capacity and dynamics of simple two-species microbial ecosystems. We specifically focus on detecting emergent biosynthetic capacity--instances in which a community growing on some medium produces and secretes metabolites that are not secreted by any member species when growing in isolation on that same medium. Using this framework to model a large collection of two-species communities on multiple media, we demonstrate that emergent biosynthetic capacity is highly prevalent. We identify commonly observed emergent metabolites and metabolic reprogramming patterns, characterizing typical mechanisms of emergent capacity. We further find that emergent secretion tends to occur in two waves, the first as soon as the two organisms are introduced, and the second when the medium is depleted and nutrients become limited. Finally, aiming to identify global community determinants of emergent capacity, we find a marked association between the level of emergent biosynthetic capacity and the functional/phylogenetic distance between community members. Specifically, we demonstrate a "Goldilocks" principle, where high levels of emergent capacity are observed when the species comprising the community are functionally neither too close, nor too distant. Taken together

  15. Capacity planning and management

    Boydell, Briony

    2011-01-01

    After reading this chapter you should be able to: • Define and measure capacity and appreciate the factors that influence it. • Assess the difficulties of matching capacity to demand. • Evaluate and apply the different strategies for matching capacity with demand in the short, medium and long term. • Analyse the impact of constraints and bottlenecks on a process and consider the Theory of Constraints. • Outline the different strategies available for both manufacturing and service operations. ...

  16. Force-Time Entropy of Isometric Impulse.

    Hsieh, Tsung-Yu; Newell, Karl M

    2016-01-01

    The relation between force and temporal variability in discrete impulse production has been viewed as independent (R. A. Schmidt, H. Zelaznik, B. Hawkins, J. S. Frank, & J. T. Quinn, 1979 ) or dependent on the rate of force (L. G. Carlton & K. M. Newell, 1993 ). Two experiments in an isometric single finger force task investigated the joint force-time entropy with (a) fixed time to peak force and different percentages of force level and (b) fixed percentage of force level and different times to peak force. The results showed that the peak force variability increased either with the increment of force level or through a shorter time to peak force that also reduced timing error variability. The peak force entropy and entropy of time to peak force increased on the respective dimension as the parameter conditions approached either maximum force or a minimum rate of force production. The findings show that force error and timing error are dependent but complementary when considered in the same framework with the joint force-time entropy at a minimum in the middle parameter range of discrete impulse.

  17. The French capacity mechanism

    2014-01-01

    The French capacity mechanism has been design to ensure security of supply in the context of the energy transition. This energy transition challenges the electricity market design with several features: peak load growth, the development of renewables, demand response,... To ensure security of supply in this context, a capacity mechanism is being implemented in France. It is a market wide capacity obligation on electricity suppliers, based on market principles. Suppliers are responsible for forecasting their obligation, which corresponds to their contribution to winter peak load, and must procure enough capacity certificates to meet their obligations. Capacity certificates are granted to capacities through a certification process, which assesses their contribution to security of supply on the basis of availability commitments. This certification process is technology neutral and performance based, associated with controls and penalties in case of non compliance. Demand Side is fully integrated in the market, either through the reduction of suppliers' capacity obligation or direct participation after certification. In addition to the expected benefits in terms of security of supply, the French capacity market will foster the development of demand response. The participation of foreign capacities will require adaptations which are scheduled in a road-map, and could pave the way for further European integration of energy policies. (authors)

  18. Heat Capacity Analysis Report

    Findikakis, A.

    2004-01-01

    The purpose of this report is to provide heat capacity values for the host and surrounding rock layers for the waste repository at Yucca Mountain. The heat capacity representations provided by this analysis are used in unsaturated zone (UZ) flow, transport, and coupled processes numerical modeling activities, and in thermal analyses as part of the design of the repository to support the license application. Among the reports that use the heat capacity values estimated in this report are the ''Multiscale Thermohydrologic Model'' report, the ''Drift Degradation Analysis'' report, the ''Ventilation Model and Analysis Report, the Igneous Intrusion Impacts on Waste Packages and Waste Forms'' report, the ''Dike/Drift Interactions report, the Drift-Scale Coupled Processes (DST and TH Seepage) Models'' report, and the ''In-Drift Natural Convection and Condensation'' report. The specific objective of this study is to determine the rock-grain and rock-mass heat capacities for the geologic stratigraphy identified in the ''Mineralogic Model (MM3.0) Report'' (BSC 2004 [DIRS 170031], Table 1-1). This report provides estimates of the heat capacity for all stratigraphic layers except the Paleozoic, for which the mineralogic abundance data required to estimate the heat capacity are not available. The temperature range of interest in this analysis is 25 C to 325 C. This interval is broken into three separate temperature sub-intervals: 25 C to 95 C, 95 C to 114 C, and 114 C to 325 C, which correspond to the preboiling, trans-boiling, and postboiling regimes. Heat capacity is defined as the amount of energy required to raise the temperature of a unit mass of material by one degree (Nimick and Connolly 1991 [DIRS 100690], p. 5). The rock-grain heat capacity is defined as the heat capacity of the rock solids (minerals), and does not include the effect of water that exists in the rock pores. By comparison, the rock-mass heat capacity considers the heat capacity of both solids and pore

  19. The Warfighting Capacity of Air Combat Command's Numbered Air Forces

    Hanser, Lawrence

    2000-01-01

    ...) of the Air Combat Command (ACC), General Richard E. Hawley, the ACC Commander, asked if RAND could offer an analysis of the number of NAFs that were needed by ACC to meet warfighting requirements...

  20. Antioxidant capacity and physical exercise

    A Marciniak

    2009-09-01

    Full Text Available The aim of this article is a presentation of current knowledge regarding the changes of plasma antioxidant capacity observed in response to physical exercise. Human body created the enzymatic and non-enzymatic systems, which play a protective role in the harmful impact of free radicals. Those two systems constitute what is known as the plasma total antioxidant capacity. The amount of reactive oxygen species (ROS and reactive nitrogen species (NOS in combination with oxidation processes increases in some tissues during physiological response to physical exercise. These changes are observed after single bout of exercise as well as after regular training. The response of human body to physical exercise can be analysed using various models of exercise test. Application of repeated type of exhaustion allows for characterizing the ability of human body to adjust to the increased energy loss and increased oxygen consumption. This article presents the characteristics of components of plasma antioxidant capacity, the mechanisms of free radicals production and their role in human body. It discusses also the currently used methods of detecting changes in total antioxidant capacity and its individual elements in response to single bout of exercise and regular training. It presents the review of literature about research performed in groups of both regularly training and low exercise activity individuals as well as in group of healthy subjects and patients with circulation diseases.

  1. Uncertainty in adaptive capacity

    Neil Adger, W.; Vincent, K.

    2005-01-01

    The capacity to adapt is a critical element of the process of adaptation: it is the vector of resources that represent the asset base from which adaptation actions can be made. Adaptive capacity can in theory be identified and measured at various scales, from the individual to the nation. The assessment of uncertainty within such measures comes from the contested knowledge domain and theories surrounding the nature of the determinants of adaptive capacity and the human action of adaptation. While generic adaptive capacity at the national level, for example, is often postulated as being dependent on health, governance and political rights, and literacy, and economic well-being, the determinants of these variables at national levels are not widely understood. We outline the nature of this uncertainty for the major elements of adaptive capacity and illustrate these issues with the example of a social vulnerability index for countries in Africa. (authors)

  2. Production of a thermostable 1,3-1,4-β-glucanase mutant in Bacillus subtilis WB600 at a high fermentation capacity and its potential application in the brewing industry.

    Niu, Chengtuo; Liu, Chunfeng; Li, Yongxian; Zheng, Feiyun; Wang, Jinjing; Li, Qi

    2018-02-01

    1,3-1,4-β-glucanase was an important biotechnological aid in the brewing industry. In a previous research, a Bacillus BglTO mutant (BglTO) with high tolerance towards high temperature and low-pH conditions was constructed and expressed in Escherichia coli. However, E. coli was not a suitable host for enzyme production in food industry. Therefore, the present work aimed to achieve the high-level expression of BglTO in Bacillus subtilis WB600 and to test its effect in Congress mashing. The β-glucanase mutant was successfully expressed in B. subtilis WB600 and favorable plasmid segregation and structural stability were observed. The maximal extracellular activity of β-glucanase in recombinant B. subtilis WB600 reached 4840.4UmL -1 after cultivation condition optimization, which was 1.94-fold higher than that before optimization. The fermentation capacity of recombinant B. subtilis reached 242.02UmL -1 h -1 , which was the highest among all reported β-glucanases. The addition of BglTO in Congress mashing significantly reduced the filtration time and viscosity of mash by 29.7% and 12.3%, respectively, which was superior to two commercial enzymes. These favorable properties indicated that B. subtilis WB600 was a suitable host for production of BglTO, which was promising for application in the brewing industry. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Bullying as an effect of intra-active material-discursive forces, anxiety of social exclusion and strategies of soothing by contempt production

    Søndergaard, Dorte Marie

    -active enactment of discursive-material phenomena, and Judith Butler’s further development of the concept of abjection, I argue bullying to be an effect of the anxiety about social exclusion. That anxiety follows intra-action among a variety of social, cultural, psychological and material forces in schools...

  4. Urban energy management today: Ten year compendium of UCETF programs. Products and expertise of the Urban Consortium Energy Task Force, 1979--1989

    1990-01-01

    The reports listed in this Overview summarize projects conducted through the Urban Consortium Energy Task Force by local government staff who have defined and implemented many of the energy strategies described above. Reports from their projects illustrate effective approaches to plan and implement these strategies, as well as software tools, surveys, and technical instruments valuable to other local government officials conducting similar projects.

  5. VARIATION IN RESISTIVE FORCE SELECTION DURING BRIEF HIGH INTENSITY CYCLE ERGOMETRY: IMPLICATIONS FOR POWER ASSESSMENT AND PRODUCTION IN ELITE KARATE PRACTITIONERS

    Julien Steven Baker

    2006-07-01

    Full Text Available The purpose of this study was to measure power values generated in elite karate fighters during brief high intensity cycle ergometry when resistive forces were derived from total - body mass (TBM or fat - free mass (FFM. Male international karate practitioners volunteered as participants (n = 11. Body density was calculated using hydrostatic weighing procedures with fat mass ascertained from body density values. Participants were required to pedal maximally on a cycle ergometer (Monark 864 against randomly assigned loads ranging from 70 g·kg-1 - 95 g·kg-1 (using a TBM or FFM protocol for 8 seconds. The resistive force that produced the highest peak power output (PPO for each protocol was considered optimal. Differences (p 0.05 were observed between time to PPO, or heart rate when the TBM and FFM protocols were compared. The findings of this study suggest that when high intensity cycle ergometer resistive forces are derived from FFM, greater peak powers can be obtained consistently in karate athletes. Resistive forces that relate to the active muscle tissue utilised during this type of exercise may need to be explored in preference to protocols that include both lean and fat masses. The findings have implications for both exercise prescription and the evaluation of experimental results concerning karate athletes

  6. Productivity

    Spring, Martin; Johnes, Geraint; Hald, Kim Sundtoft

    Productivity is increasingly critical for developed economies. It has always been important: as Paul Krugman puts it, “Productivity isn’t everything, but in the long run it is almost everything. A country’s ability to improve its standard of living over time depends almost entirely on its ability...... to raise its output per worker”(Krugman, 1994). Analyses of productivity have, by and large, been the preserve of economists. Operations Management (OM) is rooted in a similar concern for the efficient use of scarce resources; Management Accounting (MA) is concerned with the institutionalised measurement...... and management of productivity. Yet the three perspectives are rarely connected. This paper is a sketch of a literature review seeking to identify, contrast and reconcile these three perspectives. In so doing, it aims to strengthen the connections between policy and managerial analyses of productivity....

  7. High current capacity electrical connector

    Bettis, E.S.; Watts, H.L.

    1976-01-01

    An electrical connector is provided for coupling high current capacity electrical conductors such as copper busses or the like. The connector is arranged in a ''sandwiched'' configuration in which a conductor plate contacts the busses along major surfaces clamped between two stainless steel backing plates. The conductor plate is provided with contact buttons in a spaced array such that the caps of the buttons extend above the conductor plate surface to contact the busses. When clamping bolts provided through openings in the sandwiched arrangement are tightened, Belleville springs provided under the rim of each button cap are compressed and resiliently force the caps into contact with the busses' contacting surfaces to maintain a predetermined electrical contact area provided by the button cap tops. The contact area does not change with changing thermal or mechanical stresses applied to the coupled conductors

  8. Vegetation Composition, Biomass Production, Carrying Capacity ...

    Acacia tortilis, Acacia nilotica, Acacia mellifera and Acacia seyal were the most dominant shrubs with scattered Caddaba rotundifolia, Caddaba furmisa, Seddera bagshawei, Tamarix nilotica, Dobera glabra and abundant Parthenium hysterophorus, Cissus rotundifolia and C. quadrangularis. The grass biomass estimated in ...

  9. Capacity Utilization in European Railways

    Khadem Sameni, Melody; Landex, Alex

    2013-01-01

    and unprecedented approach for this aim. Relative operational efficiency of 24 European railways in capacity utilization is studied for the first time by data envelopment analysis (DEA). It deviates from previous applications of DEA in the railway industry that are conducted to analyze cost efficiency of railways....... Six DEA models quantify various aspects of micro, macro and quality of railway capacity utilization in these countries. New inputs like gross domestic product, population and area of the country help to provide a better picture of the status of railways. Passenger satisfaction data about different...... aspects of railway services in European countries has recently been quantified by European commission and are used for the first time in the literature. Invaluable insights can be inferred from the results which can provide a ground basis for railway practitioners and policy makers....

  10. Vedr.: Military capacity building

    Larsen, Josefine Kühnel; Struwe, Lars Bangert

    2013-01-01

    Military capacity building has increasingly become an integral part of Danish defence. Military capacity is a new way of thinking Danish defence and poses a new set of challenges and opportunities for the Danish military and the Political leadership. On the 12th of december, PhD. Candidate Josefine...... Kühnel Larsen and researcher Lars Bangert Struwe of CMS had organized a seminar in collaboration with Royal Danish Defense Colleg and the East African Security Governance Network. The seminar focused on some of the risks involved in Military capacity building and how these risks are dealt with from...

  11. PERHITUNGAN IDLE CAPACITY DENGAN MENGGUNAKAN CAM-I CAPACITY MODEL DALAM RANGKA EFISIENSI BIAYA PADA PT X

    Muammar Aditya

    2015-09-01

    Full Text Available Aim for this research are to analyze capacity cost which incure from company production machines and human resources whose operate the production machine using CAM-I capacity model. CAM-I capacity model is an approach which focus  upon how to manage company resources. This research initiated at PT X which focus to production activity that used small mixer machine, extruder machine, oven drying machine, enrober machine, pan coting machine which consist of hot and cold pan coating machine, and packing machine which consist of vertical packing machine and horizontal packing machine as well as human resources that operates those machine. This research focus on rate capacity, productive capacity, idle capacity, and nonproductive capacity to measure capacity cost. Result of this research shows most of the capacity owned by either by production machine or human resources are not utilized to its maximum potential. There are need to reduce capacity cost owned by production machine and human resoures to increase the product sales but if its unachieveable there will be need to increase efficiency from production machine and human resources by reducing their quantityDOI: 10.15408/ess.v4i1.1961

  12. Aerobic capacity and its correlates in patients with ankylosing spondylitis.

    Hsieh, Lin-Fen; Wei, James Cheng-Chung; Lee, Hsin-Yi; Chuang, Chih-Cheng; Jiang, Jiunn-Song; Chang, Kae-Chwen

    2016-05-01

    To evaluate aerobic capacity in patients with ankylosing spondylitis (AS) and determine possible relationships between aerobic capacity, pulmonary function, and disease-related variables. Forty-two patients with AS and 42 healthy controls were recruited in the study. Descriptive data, disease-related variables (grip strength, lumbosacral mobility, occiput-to-wall distance, chest expansion, finger-to-floor distance, Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Global Score, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and hemoglobin), and chest and thoracic spine x-rays were collected in each patient with AS. All subjects took standard pulmonary function and exercise tolerance tests, and forced vital capacity (FVC) and aerobic capacity were recorded. Both aerobic capacity and FVC in patients with AS were significantly lower than those in normal subjects (P aerobic capacity. There was significant correlation between aerobic capacity, vital capacity, chest expansion, Schober's test, cervical range of motion, and BASFI in patients with AS. Neither aerobic capacity nor vital capacity correlated with disease duration, ESR, CRP, and hemoglobin. Significantly reduced aerobic capacity and FVC were observed in patients with AS, and there was significant correlation between aerobic capacity, vital capacity, chest expansion, and BASFI. © 2014 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

  13. Evaluating Capacity Development

    She also had the dubious pleasure of checking and correcting the text numerous ... Has your organization received training or other types of support for capacity ...... processors, and consumer groups in its research and development work.

  14. Coriolis Force

    Marciuc, Daly; Solschi, Viorel

    2017-04-01

    Understanding the Coriolis effect is essential for explaining the movement of air masses and ocean currents. The lesson we propose aims to familiarize students with the manifestation of the Coriolis effect. Students are guided to build, using the GeoGebra software, a simulation of the motion of a body, related to a rotating reference system. The mathematical expression of the Coriolis force is deduced, for particular cases, and the Foucault's pendulum is presented and explained. Students have the opportunity to deepen the subject, by developing materials related to topics such as: • Global Wind Pattern • Ocean Currents • Coriolis Effect in Long Range Shooting • Finding the latitude with a Foucault Pendulum

  15. Invisible force

    Panek, Richard

    2010-01-01

    Astronomers have compiled evidence that what we always thought of as the actual universe- all the planets, stars, galaxies and matter in space -represents a mere 4% of what's out there. The rest is dark: 23% is called dark matter, 73% dark energy. Scientists have ideas about what dark matter is, but hardly any understanding about dark energy. This has led to rethinking traditional physics and cosmology. Assuming the existence of dark matter and that the law of gravitation is universal, two teams of astrophysicists, from Lawrence Berkeley National Laboratory and the Australian National University, analysed the universe's growth and to their surprise both concluded that the universe expansion is not slowing but speeding up. If the dominant force of evolution isn't gravity what is it?

  16. Revisiting Absorptive Capacity

    de Araújo, Ana Luiza Lara; Ulhøi, John Parm; Lettl, Christopher

    Absorptive capacity has mostly been perceived as a 'passive' outcome of R&D investments. Recently, however, a growing interest into its 'proactive' potentials has emerged. This paper taps into this development and proposes a dynamic model for conceptualizing the determinants of the complementary...... learning processes of absorptive capacity, which comprise combinative and adaptive capabilities. Drawing on survey data (n=169), the study concludes that combinative capabilities primarily enhance transformative and exploratory learning processes, while adaptive capabilities strengthen all three learning...

  17. High Capacity cylinder roller bearing; High Capacity Zylinderrollenlager. Ein vollrolliges Lager mit Kaefig

    Reichert, J.; Baum, J. [SKF, Schweinfurt (Germany)

    2007-07-15

    The high capacity cylinder roller bearing is an example for continuous development of SKF products and does an effective contribution to increase operational safety and offers the possibility to reduce weight and compact design. (GL)

  18. Air Force Space Situational Awareness

    2018-03-13

    time sensitivity and CyberWorx capacity. One method, which maximizes solution agility and the educational benefit to warfighters and industry...how the Air Force might best exploit commercial, academic, and foreign SSA data to improve space outcomes. Question Background & Participants Modern ...in industry and even in their personal lives. CyberWorx was asked to address the challenges of incorporating non- traditional (open source, academic

  19. Volume flexibility and capacity investment: a real options approach

    Wen, Xingang; Kort, Peter; Talman, Dolf

    2017-01-01

    This paper considers the investment decision of a firm where it has to decide about the timing and capacity. We obtain that in a fast-growing market, right after investment the firm produces below capacity, where the utilization rate (the proportion of capacity that is used for production right

  20. Volume Flexibility and Capacity Investment : A Real Options Approach

    Wen, X.; Kort, P.M.; Talman, A.J.J.

    2015-01-01

    This paper considers the investment decision of a firm where it has to decide about the timing and capacity. We obtain that in a fast growing market, right after investment the firm produces below capacity, where the utilization rate (the proportion of capacity that is used for production right