WorldWideScience

Sample records for focus coil safety

  1. Response to Absorber-Focus Coil Preliminary Safety Review Panel

    International Nuclear Information System (INIS)

    Barr, Giles; Baynham, Elwyn; Black, Edgar; Bradshaw, Tom; Cummings, Mary Anne; Green, Michael A.; Ishimoto, Shigeru; Ivanyushenkov, Yury; Lau, Wing; Zisman, Michael S.

    2004-01-01

    In this document we provide responses to the various issues raised in the report of the Preliminary Safety Review Panel (see http://mice.iit.edu/mnp/MICE0069.pdf). In some cases we have made design changes in response to the Panels suggestions. In other cases, we have chosen not to do so. In a few cases, we indicate our plans, although the tasks have not yet been completed. For simplicity, the responses are organized along the same lines as those of the Panel Report

  2. MICE - Absorber and focus coil safety working group design document: Preliminary design and assessments

    International Nuclear Information System (INIS)

    Barr, Giles; Baynham, Elwyn; Black, Edgar; Bradshaw, Tom; Cummings, Mary Anne; Green, Michael A.; Ishimoto, Shigeru; Ivanyushenkov, Yury; Lau, Wing; Zisman, Michael

    2003-01-01

    A Neutrino Factory based on a muon storage ring is the ultimate tool for studies of neutrino oscillations, including possibly the discovery of leptonic CP violation. it is also the first step toward a muon collider. To develop a stored-muon-beam facility to serve as a Neutrino Factory, it is necessary to ''cool'' a muon beam (decrease its phase-space volume). The short lifetime of the muon, 2.2 (micro)s at rest, eliminates all currently demonstrated cooling techniques and requires that a new, heretofore untried, technique--ionization cooling--be employed. Although ionization cooling of muons has never been demonstrated in practice, it has been shown by end-to-end simulation and design studies to be an important factor both for the performance and for the cost of a Neutrino Factory. This motivates an international program of R and D, including an experimental demonstration at Rutherford Appleton Laboratory (RAL). The aims of the international Muon Ionization Cooling Experiment are: (1) to show that it is possible to design, engineer and build a section of cooling channel capable of giving the desired performance for a Neutrino Factory; and (2) to place it in a muon beam and measure its performance in various modes of operation and beam conditions, thereby investigating the limits and practicality of cooling. The MICE collaboration has designed an experiment in which a section of an ionization cooling channel is exposed to a muon beam. This cooling channel assembles liquid-hydrogen absorbers providing energy loss and high-gradient radio frequency (RF) cavities to re-accelerate the particles, all tightly contained in a magnetic channel. It reduces the beam transverse emittance by > 10% for muon momenta between 140 and 240 MeV/c. The layout of the experiment is shown. They utilize one complete magnetic cell of the cooling channel, comprising three absorber-focus-coil (AFC) modules and two RF-coupling-coil (RFCC) modules. Spectrometers placed before and after the

  3. Focused surface coil for MR imaging of the pituitary

    International Nuclear Information System (INIS)

    Harms, S.E.; Sherry, C.S.; Youshimura, L.; Lokken, R.; Hyde, J.S.

    1987-01-01

    A specially designed surface coil for pituitary MR imaging results in improved image quality over that achieved with conventional pituitary Mr imaging. The coil consists of connected planar pair coils with a variable intercoil distance to accommodate differences in head size. The sensitive field is focused deep to the surface between the two planar pairs. This arrangement optimizes the signal-to-noise ratio and allows better gradient magnification of the pituitary region. Fifteen subjects with a variety of pituitary disorders were imaged

  4. Designing stellarator coils by a modified Newton method using FOCUS

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart R.; Song, Yuntao; Wan, Yuanxi

    2018-06-01

    To find the optimal coils for stellarators, nonlinear optimization algorithms are applied in existing coil design codes. However, none of these codes have used the information from the second-order derivatives. In this paper, we present a modified Newton method in the recently developed code FOCUS. The Hessian matrix is calculated with analytically derived equations. Its inverse is approximated by a modified Cholesky factorization and applied in the iterative scheme of a classical Newton method. Using this method, FOCUS is able to recover the W7-X modular coils starting from a simple initial guess. Results demonstrate significant advantages.

  5. System safety education focused on flight safety

    Science.gov (United States)

    Holt, E.

    1971-01-01

    The measures necessary for achieving higher levels of system safety are analyzed with an eye toward maintaining the combat capability of the Air Force. Several education courses were provided for personnel involved in safety management. Data include: (1) Flight Safety Officer Course, (2) Advanced Safety Program Management, (3) Fundamentals of System Safety, and (4) Quantitative Methods of Safety Analysis.

  6. Periprocedural safety of aneurysm embolization with the Medina Coil System: the early human experience.

    Science.gov (United States)

    Turk, Aquilla S; Maia, Orlando; Ferreira, Christian Candido; Freitas, Diogo; Mocco, J; Hanel, Ricardo

    2016-02-01

    Intracranial saccular aneurysms, if untreated, carry a high risk of morbidity and mortality from intracranial bleeding. Embolization coils are the most common treatment. We describe the periprocedural safety and performance of the initial human experience with the next generation Medina Coil System. The Medina Coil System is a layered three-dimensional coil made from a radiopaque, shape set core wire, and shape memory alloy outer coil filaments. Nine aneurysms in five patients were selected for treatment with the Medina Coil System. Nine aneurysms in five patients, ranging from 5 to 17 mm in size in various locations, were treated with the Medina Coil System. No procedural or periprocedural complications were encountered. Procedure times, number of coils used to treat the aneurysm, and use of adjunctive devices were much less than anticipated if conventional coil technology had been used. The Medina Coil System is a next generation coil that combines all of the familiar and expected procedural safety and technique concepts associated with conventional coils. We found improved circumferential aneurysm filling, which may lead to improved long term outcomes, with fewer devices and faster operating times. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  7. Quench and safety tests on a toroidal field coil of Tore Supra

    International Nuclear Information System (INIS)

    Ciazynski, D.; Cure, C.; Duchateau, J.L.

    1987-01-01

    As a part of the safety analysis of the magnet, three quenches have been initiated in one of the TF coils in the Saclay test facility. While transporting a given current, the coil is insulated from the refrigerator: the temperatures of the helium and of the coil increase slowly on account of thermal losses. At the current sharing temperature a quench rapidly propagates and the protection system makes the coil discharge in the dump resistor. At three levels of current, electrical, thermal and hydraulic measurements have been performed. All these results are taken into account for the safety design of TORE SUPRA

  8. Focal point determination in magnetic resonance-guided focused ultrasound using tracking coils.

    Science.gov (United States)

    Svedin, Bryant T; Beck, Michael J; Hadley, J Rock; Merrill, Robb; de Bever, Joshua T; Bolster, Bradley D; Payne, Allison; Parker, Dennis L

    2017-06-01

    To develop a method for rapid prediction of the geometric focus location in MR coordinates of a focused ultrasound (US) transducer with arbitrary position and orientation without sonicating. Three small tracker coil circuits were designed, constructed, attached to the transducer housing of a breast-specific MR-guided focused US (MRgFUS) system with 5 degrees of freedom, and connected to receiver channel inputs of an MRI scanner. A one-dimensional sequence applied in three orthogonal directions determined the position of each tracker, which was then corrected for gradient nonlinearity. In a calibration step, low-level heating located the US focus in one transducer position orientation where the tracker positions were also known. Subsequent US focus locations were determined from the isometric transformation of the trackers. The accuracy of this method was verified by comparing the tracking coil predictions to thermal center of mass calculated using MR thermometry data acquired at 16 different transducer positions for MRgFUS sonications in a homogeneous gelatin phantom. The tracker coil predicted focus was an average distance of 2.1 ± 1.1 mm from the thermal center of mass. The one-dimensional locator sequence and prediction calculations took less than 1 s to perform. This technique accurately predicts the geometric focus for a transducer with arbitrary position and orientation without sonicating. Magn Reson Med 77:2424-2430, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  9. Single-Coil Defibrillator Leads Yield Satisfactory Defibrillation Safety Margin in Hypertrophic Cardiomyopathy.

    Science.gov (United States)

    Okamura, Hideo; Friedman, Paul A; Inoue, Yuko; Noda, Takashi; Aiba, Takeshi; Yasuda, Satoshi; Ogawa, Hisao; Kamakura, Shiro; Kusano, Kengo; Espinosa, Raul E

    2016-09-23

    Single-coil defibrillator leads have gained favor because of their potential ease of extraction. However, a high defibrillation threshold remains a concern in patients with hypertrophic cardiomyopathy (HCM), and in many cases, dual-coil leads have been used for this patient group. There is little data on using single-coil leads for HCM patients. We evaluated 20 patients with HCM who received an implantable cardioverter-defibrillator (ICD) on the left side in combination with a dual-coil lead. Two sets of defibrillation tests were performed in each patient, one with the superior vena cava (SVC) coil "on" and one with the SVC coil "off". ICDs were programmed to deliver 25 joules (J) for the first attempt followed by maximum energy (35 J or 40 J). Shock impedance and shock pulse width at 25 J in each setting as well as the results of the shock were analyzed. All 25-J shocks in both settings successfully terminated ventricular fibrillation. However, shock impedance and pulse width increased substantially with the SVC coil programmed "off" compared with "on" (66.4±6.1 ohm and 14.0±1.3 ms "off" vs. 41.9±5.0 ohm and 9.3±0.8 ms "on", Psatisfactory safety margin for 35-J devices. Single-coil leads appear appropriate for left-sided implantation in this patient group. (Circ J 2016; 80: 2199-2203).

  10. Safety climate and firefighting: Focus group results.

    Science.gov (United States)

    DeJoy, David M; Smith, Todd D; Dyal, Mari-Amanda

    2017-09-01

    Firefighting is a hazardous occupation and there have been numerous calls for fundamental changes in how fire service organizations approach safety and balance safety with other operational priorities. These calls, however, have yielded little systematic research. As part of a larger project to develop and test a model of safety climate for the fire service, focus groups were used to identify potentially important dimensions of safety climate pertinent to firefighting. Analyses revealed nine overarching themes. Competency/professionalism, physical/psychological readiness, and that positive traits sometimes produce negative consequences were themes at the individual level; cohesion and supervisor leadership/support at the workgroup level; and politics/bureaucracy, resources, leadership, and hiring/promotion at the organizational level. A multi-level perspective seems appropriate for examining safety climate in firefighting. Safety climate in firefighting appears to be multi-dimensional and some dimensions prominent in the general safety climate literature also seem relevant to firefighting. These results also suggest that the fire service may be undergoing transitions encompassing mission, personnel, and its fundamental approach to safety and risk. These results help point the way to the development of safety climate measures specific to firefighting and to interventions for improving safety performance. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

  11. Safety, training focus of combined organization

    Energy Technology Data Exchange (ETDEWEB)

    Toop, L.

    2006-03-15

    This article presented details of Enform, a company that coordinates safety programs and training for new employees in the oil and gas industry. Enform was created when the Petroleum Industry Training Services merged with the Canadian Petroleum Safety Council. The aim of Enform is to ensure continuous improvements in health and safety within the industry by reducing working injuries and promoting health and safety practices. The companies merged to eliminate duplication of services and allow associates further opportunities for advanced training. In 2005, Enform trained an estimated 155,000 students, and a number of new courses were introduced and updated. A franchise program was extended and a training council was formed to offer direction and guidance to the oil industry. Enform focuses on sharing information among companies, as well as working to harmonize safety regulations across provincial borders. A task force was recently created by the company with a specific focus on drug and alcohol abuse. Other concerns include driver safety and driver interactions with wildlife. Enform is mainly focused on the traditional oil industry, and has had little entry into the oil sands industry. It was concluded that increased activity in the oil and gas industry will remain Enform's biggest challenge in the next few years. Plans for Enform's increased involvement in the offshore oil and gas industry were also discussed. 4 figs.

  12. Design and application of surface coils for MR imaging with consideration of patient safety

    International Nuclear Information System (INIS)

    Bader, R.; Zabel, H.J.; Gehrig, J.; Lorenz, W.J.

    1987-01-01

    Problems concerning the safety of the patient have arisen by increasing the magnetic field for MR imaging and MR spectroscopy up to 2 T. High electric potentials result on the radio frequency (RF) that antennas in some cases are situated directly on or even inside the body. Transmit pulses can induce high voltages and currents in a separate receiver coil being resonant. Intensive RF fields emerging from the receiver coil may severely heat the conductive body tissue. Principles for suppressing the induced voltages and for detuning the antenna are described. General rules for the design of antennas and their application are discussed

  13. Design of voice coil motor dynamic focusing unit for a laser scanner

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Moon G.; Kim, Gaeun; Lee, Chan-Woo; Lee, Soo-Hun; Jeon, Yongho, E-mail: princaps@ajou.ac.kr [Department of Mechanical Engineering, Ajou University, San 5, Woncheon-dong, Yeongtong-gu, Suwon-si, Gyeonggi-do 443-749 (Korea, Republic of)

    2014-04-15

    Laser scanning systems have been used for material processing tasks such as welding, cutting, marking, and drilling. However, applications have been limited by the small range of motion and slow speed of the focusing unit, which carries the focusing optics. To overcome these limitations, a dynamic focusing system with a long travel range and high speed is needed. In this study, a dynamic focusing unit for a laser scanning system with a voice coil motor (VCM) mechanism is proposed to enable fast speed and a wide focusing range. The VCM has finer precision and higher speed than conventional step motors and a longer travel range than earlier lead zirconium titanate actuators. The system has a hollow configuration to provide a laser beam path. This also makes it compact and transmission-free and gives it low inertia. The VCM's magnetics are modeled using a permeance model. Its design parameters are determined by optimization using the Broyden–Fletcher–Goldfarb–Shanno method and a sequential quadratic programming algorithm. After the VCM is designed, the dynamic focusing unit is fabricated and assembled. The permeance model is verified by a magnetic finite element method simulation tool, Maxwell 2D and 3D, and by measurement data from a gauss meter. The performance is verified experimentally. The results show a resolution of 0.2 μm and travel range of 16 mm. These are better than those of conventional focusing systems; therefore, this focusing unit can be applied to laser scanning systems for good machining capability.

  14. System safety education focused on industrial engineering

    Science.gov (United States)

    Johnston, W. L.; Morris, R. S.

    1971-01-01

    An educational program, designed to train students with the specific skills needed to become safety specialists, is described. The discussion concentrates on application, selection, and utilization of various system safety analytical approaches. Emphasis is also placed on the management of a system safety program, its relationship with other disciplines, and new developments and applications of system safety techniques.

  15. Road safety 'results focus' - ready to launch?

    CSIR Research Space (South Africa)

    Labuschagne, FJJ

    2016-07-01

    Full Text Available The results of road safety interventions in South Africa are disappointing and the cost of road safety related casualties and damage and drain on public resources are possibly to the upper side of the typical range of 2 to 3 per cent of Gross...

  16. System safety education focused on system management

    Science.gov (United States)

    Grose, V. L.

    1971-01-01

    System safety is defined and characteristics of the system are outlined. Some of the principle characteristics include role of humans in hazard analysis, clear language for input and output, system interdependence, self containment, and parallel analysis of elements.

  17. Offshore regulators focus on incentives for safety

    Energy Technology Data Exchange (ETDEWEB)

    Reid, W.

    2000-11-27

    Strict safety regulations in effect at offshore drilling sites are discussed. The guiding principle in all existing regulation is that while economic or industrial considerations are important, the value and the concern for human life is paramount. Should some tragic event occur at an offshore drilling site that is shown to have been caused by negligence of an operator, there is no question at all that the regulatory authority, in this case the Canada-Newfoundland Offshore Petroleum Board (CNOPB), would take the negligent operator to court. Nevertheless, Canadian authorities remain confident that encouragement of maintaining a safe working environment is likely to be more successful in ensuring workplace safety than threats of punishment. Indeed, Canadian regulators have, in recent times, shown a tendency to move towards performance-based systems, as opposed to the more usual prescriptive or rule-bound regulatory regime. This new approach involves setting targets and giving companies the responsibility to implement measures to reach the targets rather than relying on government instructions. Still, performance-based regulation in Canada is relatively new and some regulations remain prescriptive. Examples are the requirement for two immersion suits and two lifeboat seats for every worker on a drilling unit.

  18. Investigation of shape, position, and permeability of shielding material in quadruple butterfly coil for focused transcranial magnetic stimulation

    Science.gov (United States)

    Rastogi, Priyam; Zhang, Bowen; Tang, Yalun; Lee, Erik G.; Hadimani, Ravi L.; Jiles, David C.

    2018-05-01

    Transcranial magnetic stimulation has been gaining popularity in the therapy for several neurological disorders. A time-varying magnetic field is used to generate electric field in the brain. As the development of TMS methods takes place, emphasis on the coil design increases in order to improve focal stimulation. Ideally reduction of stimulation of neighboring regions of the target area is desired. This study, focused on the improvement of the focality of the Quadruple Butterfly Coil (QBC) with supplemental use of different passive shields. Parameters such as shape, position and permeability of the shields have been explored to improve the focus of stimulation. Results have been obtained with the help of computer modelling of a MRI derived heterogeneous head model over the vertex position and the dorsolateral prefrontal cortex position using a finite element tool. Variables such as maximum electric field induced on the grey matter and scalp, volume and area of stimulation above half of the maximum value of electric field on the grey matter, and ratio of the maximum electric field in the brain versus the scalp have been investigated.

  19. HydroCoil as an adjuvant to bare platinum coil treatment of 100 cerebral aneurysms

    International Nuclear Information System (INIS)

    Fanning, Noel F.; Berentei, Zsolt; Brennan, Paul R.; Thornton, John

    2007-01-01

    Introduction The overall safety of the HydroCoil, an expansile hybrid hydrogel-platinum coil, is unknown. We report a prospective observational study of our first 100 cerebral aneurysms treated with HydroCoils, focusing on safety and initial efficacy.Methods Indications, procedural complications, clinical and angiographic outcomes were recorded. Packing density, number of coils deployed and angiographic results were compared with those in a matched control group of 100 aneurysms treated solely with bare platinum coils. HydroCoil complication rates were compared to bare platinum coil rates at our institution and in published series. Results Adjuvant HydroCoil treatment led to increased mean percentage aneurysm filling compared to controls (50 ± 21% versus 27 ± 13%, P < 0.001). Immediate posttreatment angiographic results showed significantly (P < 0.001) more complete occlusions and fewer incomplete (<95%) occlusions compared to controls. Intermediate follow-up angiograms (median 7.5 months) in 63 aneurysms showed a trend towards fewer incomplete occlusions with HydroCoil treatment. There were significantly fewer major recurrences with HydroCoil treatment compared to the control treatment (9.5% versus 22.6%, P 0.046). In the adjuvant HydroCoil group, major recurrent aneurysms had significantly less percentage volume packing with HydroCoils than non-recurrent aneurysms (50.3 ± 5.0% versus 65.3 ± 18.0%, P = 0.04). There was a 12% procedural complication rate, 6% procedural morbidity and 1% mortality rate, similar to institutional and reported bare platinum coil complication rates.Conclusion HydroCoils can be safely deployed with a similar complication rate to bare platinum coils. They result in improved aneurysm filling. Intermediate follow-up angiography showed significantly fewer major recurrences. Long-term follow-up is required to confirm initial improved stability. (orig.)

  20. Treatment of emphysema using bronchoscopic lung volume reduction coil technology : an update on efficacy and safety

    NARCIS (Netherlands)

    Hartman, Jorine E.; Klooster, Karin; ten Hacken, Nick H. T.; Slebos, Dirk-Jan

    2015-01-01

    In the last decade several promising bronchoscopic lung volume reduction (BLVR) treatments were developed and investigated. One of these treatments is BLVR treatment with coils. The advantage of this specific treatment is that it works independently of collateral flow, and also shows promise for

  1. Stent-assisted coil embolization of aneurysms with small parent vessels: safety and efficacy analysis.

    Science.gov (United States)

    Kühn, Anna Luisa; Hou, Samuel Y; Puri, Ajit S; Silva, Christine F; Gounis, Matthew J; Wakhloo, Ajay K

    2016-06-01

    Stent-assisted coil embolization (SACE) is a viable therapeutic approach for wide-neck intracranial aneurysms. However, it can be technically challenging in small cerebral vessels (≤2 mm). To present our experience with stents approved for SACE in aneurysms with small parent arteries. All patients who underwent stent-assisted aneurysm treatment with either a Neuroform or an Enterprise stent device at our institution between June 2006 and October 2012 were identified. Additionally, we evaluated each patient's vascular risk factors, aneurysm characteristics (ruptured vs non-ruptured, incidental finding, recanalized) and follow-up angiography data. A total of 41 patients with 44 aneurysms met our criteria, including 31 women and 10 men. Most of the aneurysms were located in the anterior circulation (75%). Stent placement in vessels 1.2-2 mm in diameter was successful in 93.2%. Thromboembolic complications occurred in 6 cases and vessel straightening was seen in 1 case only. Initial nearly complete to complete aneurysm obliteration was achieved in 88.6%. Six-month follow-up angiography showed coil compaction in three cases, one asymptomatic in-stent stenosis and stent occlusion. Twelve to 20-months' follow-up showed stable coil compaction in two patients compared with previous follow-up, and aneurysm recanalization in two patients. Twenty-four to 36-months' follow-up showed further coil compaction in one of these patients and aneurysm recanalization in a previous case of stable coil compaction on mid-term follow-up. Our results suggest that SACE of aneurysms with small parent vessels is feasible in selected cases and shows good long-term patency rates of parent arteries. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. Process management - critical safety issues with focus on risk management

    International Nuclear Information System (INIS)

    Sanne, Johan M.

    2005-12-01

    Organizational changes focused on process orientation are taking place among Swedish nuclear power plants, aiming at improving the operation. The Swedish Nuclear Power Inspectorate has identified a need for increased knowledge within the area for its regulatory activities. In order to analyze what process orientation imply for nuclear power plant safety a number of questions must be asked: 1. How is safety in nuclear power production created currently? What significance does the functional organization play? 2. How can organizational forms be analysed? What consequences does quality management have for work and for the enterprise? 3. Why should nuclear power plants be process oriented? Who are the customers and what are their customer values? Which customers are expected to contribute from process orientation? 4. What can one learn from process orientation in other safety critical systems? What is the effect on those features that currently create safety? 5. Could customer values increase for one customer without decreasing for other customers? What is the relationship between economic and safety interests from an increased process orientation? The deregulation of the electricity market have caused an interest in increased economic efficiency, which is the motivation for the interest in process orientation. among other means. It is the nuclear power plants' owners and the distributors (often the same corporations) that have the strongest interest in process orientation. If the functional organization and associated practices are decomposed, the prerequisites of the risk management regime changes, perhaps deteriorating its functionality. When nuclear power operators consider the introduction of process orientation, the Nuclear Power Inspectorate should require that 1. The operators perform a risk analysis beforehand concerning the potential consequences that process orientation might convey: the analysis should contain a model specifying how safety is currently

  3. Development of a compact HTS lead unit for the SC correction coils of the SuperKEKB final focusing magnet system

    Energy Technology Data Exchange (ETDEWEB)

    Zong, Zhanguo, E-mail: zhanguo.zong@kek.jp; Ohuchi, Norihito; Tsuchiya, Kiyosumi; Arimoto, Yasushi

    2016-09-11

    Forty-three superconducting (SC) correction coils with maximum currents of about 60 A are installed in the SuperKEKB final focusing magnet system. Current leads to energize the SC correction coils should have an affordable heat load and fit the spatial constraints in the service cryostat where the current leads are installed. To address the requirements, design optimization of individual lead was performed with vapor cooled current lead made of a brass material, and a compact unit was designed to accommodate eight current leads together in order to be installed with one port in the service cryostat. The 2nd generation high temperature SC (HTS) tape was adopted and soldered at the cold end of the brass current lead to form a hybrid HTS lead structure. A prototype of the compact lead unit with HTS tape was constructed and tested with liquid helium (LHe) environment. This paper presents a cryogenic measurement system to simulate the real operation conditions in the service cryostat, and analysis of the experimental results. The measured results showed excellent agreement with the theoretical analysis and numerical simulation. In total, 11 sets of the compact HTS lead units were constructed for the 43 SC correction coils at KEK. One set from the mass production was tested in cryogenic conditions, and exhibited the same performance as the prototype. The compact HTS lead unit can feed currents to four SC correction coils simultaneously with the simple requirement of controlling and monitoring helium vapor flow, and has a heat load of about 0.762 L/h in terms of LHe consumption. - Highlights: • The requirements of the SC correction coils on current leads are introduced. • The optimum design of the brass vapor cooled current lead is described. • The compact structure of eight leads with HTS tape is presented. • The theoretical, numerical, and experimental results are compared. • The current lead heat load is evaluated for cryogenic system.

  4. Focus on patient safety all day, every day.

    Science.gov (United States)

    2015-06-01

    Case managers may think their job doesn't involve patient safety, but they promote safety by ensuring a safe discharge and are in a position to see safety breaches and mistakes all over the hospital. CMS includes discharge planning in its worksheets for surveyors to use to assess a hospital's compliance with Medicare Conditions of Participation. Because they work with patients from admission to discharge, case managers know which clinicians are competent, those who are not, and may observe safety breaches like failure to wash hands and leaving the catheter in too long. Case managers should spend enough time with their patients to know their situations at home and their support systems and use the information to create workable and safe discharge plans. Hospitals should create an environment and a culture where case managers and other clinicians feel comfortable speaking up when they see safety breaches.

  5. An 8/15-channel Tx/Rx head neck RF coil combination with region-specific B1 + shimming for whole-brain MRI focused on the cerebellum at 7T.

    Science.gov (United States)

    Pfaffenrot, Viktor; Brunheim, Sascha; Rietsch, Stefan H G; Koopmans, Peter J; Ernst, Thomas M; Kraff, Oliver; Orzada, Stephan; Quick, Harald H

    2018-02-09

    To design and evaluate an 8/15-channel transmit/receive (Tx/Rx) head-neck RF coil combination with region-specific B1+ shimming for whole-brain MRI with focus on improved functional MRI of the cerebellum at 7 T. An 8-channel transceiver RF head coil was combined with a 7-channel receive-only array. The noise parameters and acceleration capabilities of this 8Tx/15Rx coil setup were compared with a commercially available 1Tx/32Rx RF head coil. Region-specific 8-channel B1+ shimming was applied when using the 8Tx/15Rx RF coil. To evaluate the capability for functional MRI of the cerebellum, temporal SNR and statistical nonparametric maps for finger-tapping experiments with 14 healthy subjects were derived by applying a variable slice thickness gradient-echo echo-planar functional MRI sequence. The 8Tx/15Rx setup had a lower maximum noise correlation between channels, but higher average correlations compared with the 1Tx/32Rx coil. Both RF coils exhibited identical g-factors in the cerebellum with R = 3 acceleration. The enlarged FOV of the 8Tx/15Rx coil in combination with region-specific B1+ shimming increased homogeneity of the transmission field and temporal SNR in caudal cerebellar regions. Temporal SNR losses in cranial parts were reduced, resulting in more highly significant voxels in the caudally activated areas and identical patterns in the cranial cerebellar parts during a finger-tapping task. Compared with the 1Tx/32Rx RF coil, the presented 8Tx/15Rx RF coil combination successfully improves functional MRI of the human cerebellum at 7 T while maintaining whole-brain coverage. A clear temporal SNR gain in caudal cerebellar regions is shown. © 2018 International Society for Magnetic Resonance in Medicine.

  6. Review of actinide nitride properties with focus on safety aspects

    Energy Technology Data Exchange (ETDEWEB)

    Albiol, Thierry [CEA Cadarache, St Paul Lez Durance Cedex (France); Arai, Yasuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-12-01

    This report provides a review of the potential advantages of using actinide nitrides as fuels and/or targets for nuclear waste transmutation. Then a summary of available properties of actinide nitrides is given. Results from irradiation experiments are reviewed and safety relevant aspects of nitride fuels are discussed, including design basis accidents (transients) and severe (core disruptive) accidents. Anyway, as rather few safety studies are currently available and as many basic physical data are still missing for some actinide nitrides, complementary studies are proposed. (author)

  7. Use of the safety case to focus KMS applications - 16348

    International Nuclear Information System (INIS)

    Osawa, Hideaki; Hioki, Kazumasa; Umeki, Hiroyuki; Takase, Hiroyasu; McKinley, Ian

    2009-01-01

    The safety case, as defined in Japan, is an integrated set of arguments to show that a repository is sufficiently safe during both operational and post-closure phases. It explicitly includes the findings of a safety assessment and a demonstration of confidence in these findings. It is developed in a stepwise manner, with provisional cases used to support decisions at major project milestones. Social acceptance is acknowledged to be critical and hence a safety case includes not only technical components, but also the arguments required to explain fundamental issues to all key stakeholders. In the JAEA KMS project, the safety case has been found useful as a framework that allows all supporting R and D to be seen in the context of its applicability. Various tools have been examined to develop associated argumentation models and they have been seen to provide an overview that is valuable to both the users and producers of knowledge. The paper will review progress to date in this work, with illustrative examples of argumentation networks and an outline of future developments and challenges. (authors)

  8. Management by process based systems and safety focus

    International Nuclear Information System (INIS)

    Rydnert, Bo; Groenlund, Bjoern

    2005-12-01

    An initiative from The Swedish Nuclear Power Inspectorate led to this study carried out in the late autumn of 2005. The objective was to understand in more detail how an increasing use of process management affects organisations, on the one hand regarding risks and security, on the other hand regarding management by objectives and other management and operative effects. The main method was interviewing representatives of companies and independent experts. More than 20 interviews were carried out. In addition a literature study was made. All participating companies are using Management Systems based on processes. However, the methods chosen, and the results achieved, vary extensively. Thus, there are surprisingly few examples of complete and effective management by processes. Yet there is no doubt that management by processes is effective and efficient. Overall goals are reached, business results are achieved in more reliable ways and customers are more satisfied. The weaknesses found can be translated into a few comprehensive recommendations. A clear, structured and acknowledged model should be used and the processes should be described unambiguously. The changed management roles should be described and obeyed extremely legibly. New types of process objectives need to be formulated. In addition one fact needs to be observed and effectively fended off. Changes are often met by mental opposition on management level, as well as among co-workers. This fact needs attention and leadership. Safety development is closely related to the design and operation of a business management system and its continual improvement. A deep understanding of what constitutes an efficient and effective management system affects the understanding of safety. safety culture and abilities to achieve safety goals. Concerning risk, the opinions were unambiguous. Management by processes as such does not result in any further risks. On the contrary. Processes give a clear view of production and

  9. Commercial applications for COIL

    Science.gov (United States)

    Solomon, Wayne C.; Carroll, David L.; King, D. M.; Fockler, L. A.; Stromberg, D. S.; Sexauer, M.; Milmoe, A.; Sentman, Lee H.

    2000-01-01

    The chemical oxygen-iodine laser (COIL) is a high power, fiber deliverable tool, which can be used for a number of different industrial applications. COIL is of particular interest because of its short fiber deliverable wavelength, high scaleable continuous wave power, and excellent material interaction properties. In past research the University of Illinois at Urbana-Champaign identified and decommissioning and decontamination (DD) of nuclear facilities as a primary focus for COIL technology. DD will be a major challenge in the coming decades. The use of a robotically driven fiber delivered cutting/ablation tool in contaminated areas promises to lower risks to workers for the DD mission. Further, the high cutting speed of COIL will significantly reduce the time required to cut contaminated equipment, reducing costs. The high power of COIL will permit the dismantling of thick stacks of piping and equipment as well as reactor vessels. COIL is very promising for the removal of material from contaminated surfaces, perhaps to depths thicker than an inch. Laser cutting and ablation minimizes dust and fumes, which reduces the required number of high efficiency particulate accumulator filters, thus reducing costly waste disposal. Other potential industrial applications for COIL are shipbuilding, automotive manufacturing, heavy machinery manufacturing, tasks requiring underwater cutting or welding, and there appear to be very promising applications for high powers lasers in the oil industry.

  10. The discrepancy between human peripheral nerve chronaxie times as measured using magnetic and electric field stimuli: the relevance to MRI gradient coil safety

    International Nuclear Information System (INIS)

    Recoskie, Bryan J; Chronik, Blaine A; Scholl, Timothy J

    2009-01-01

    Peripheral nerve stimulation (PNS) resulting from electric fields induced from the rapidly changing magnetic fields of gradient coils is a concern in MRI. Nerves exposed to either electric fields or changing magnetic fields would be expected to display consistent threshold characteristics, motivating the direct application of electric field exposure criteria from the literature to guide the development of gradient magnetic field exposure criteria for MRI. The consistency of electric and magnetic field exposures was tested by comparing chronaxie times for electric and magnetic PNS curves for 22 healthy human subjects. Electric and magnetic stimulation thresholds were measured for exposure of the forearm using both surface electrodes and a figure-eight magnetic coil, respectively. The average chronaxie times for the electric and magnetic field conditions were 109 ± 11 μs and 651 ± 53 μs (±SE), respectively. We do not propose that these results call into question the basic mechanism, namely that rapidly switched gradient magnetic fields induce electric fields in human tissues, resulting in PNS. However, this result does motivate us to suggest that special care must be taken when using electric field exposure data from the literature to set gradient coil PNS safety standards in MRI.

  11. The dual effects of leading for safety: The mediating role of employee regulatory focus.

    Science.gov (United States)

    Kark, Ronit; Katz-Navon, Tal; Delegach, Marianna

    2015-09-01

    This study examined the underlying mechanisms through which transformational and transactional leadership influence employee safety behaviors. Linking leadership theory with self-regulatory focus (SRF) theory, we examined a model of dual effects of leadership on safety initiative and safety compliance behaviors as mediated by promotion and prevention self-regulations. We conducted an experimental study (N = 107), an online study (N = 99) and a field study (N = 798 employees and 49 managers). Results demonstrated that followers' situational promotion focus mediated the positive relationship between transformational leadership and safety initiative behaviors. Through all 3 studies, transactional active leadership was positively associated with followers' situational prevention focus, however, the association between followers' prevention focus and safety compliance behaviors was inconsistent, showing the expected mediation relationships in the experimental setting, but not in the online and field studies. We discuss theoretical and practical implications of the findings. (c) 2015 APA, all rights reserved).

  12. A study on Impact of Safety Culture on Safety Behavior: Moderating effect of Prevention Focus

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Sun Chul; Jung, Su Jin; Choi, Young Sung [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    In modern society, it has been acknowledged that disasters caused by civilization became inevitable. With growing attention to role of human as one component of the system to cope with accident to prevent disasters, various efforts have been deployed to keep safety. Most of the industries with high hazard have adopted the term as their banner in the efforts to promote safety in their installations and operations. Recently, the Fukushima nuclear power plants(NPPs) accident happened in Japan in 2011 resulted in great impact over the world and have highlighted the importance of safety culture again.

  13. A study on Impact of Safety Culture on Safety Behavior: Moderating effect of Prevention Focus

    International Nuclear Information System (INIS)

    Hwang, Sun Chul; Jung, Su Jin; Choi, Young Sung

    2016-01-01

    In modern society, it has been acknowledged that disasters caused by civilization became inevitable. With growing attention to role of human as one component of the system to cope with accident to prevent disasters, various efforts have been deployed to keep safety. Most of the industries with high hazard have adopted the term as their banner in the efforts to promote safety in their installations and operations. Recently, the Fukushima nuclear power plants(NPPs) accident happened in Japan in 2011 resulted in great impact over the world and have highlighted the importance of safety culture again

  14. Focus State Roadway Departure Safety Plans and High Friction Surface Treatments Peer Exchange : an RPSCB Peer Exchange

    Science.gov (United States)

    2014-08-01

    This report summarizes the Focus State Roadway Departure Safety Plans and High Friction Surface Treatments Peer Exchange, held in Birmingham, Alabama, sponsored by the Federal Highway Administration (FHWA) Office of Safetys Roadway Safety Professi...

  15. PSA analysis focused on Mochovce NPP safety measures evaluation from operational safety point of view

    International Nuclear Information System (INIS)

    Cillik, I.; Vrtik, L.

    2001-01-01

    Mochovce NPP consists of four reactor units of WWER 440/V213 type and it is located in the south-middle part of Slovakia. At present first unit operated and the second one under the construction finishing. As these units represent second generation of WWER reactor design, the additional safety measures (SM) were implemented to enhance operational and nuclear safety according to the recommendations of performed international audits and operational experience based on exploitation of other similar units (as Dukovany and J. Bohunice NPPs). These requirements result into a number of SMs grouped according to their purpose to reach recent international requirements on nuclear and operational safety. The paper presents the bases used for safety measures establishing including their grouping into the comprehensive tasks covering different areas of safety goals as well as structural organization of a project management of including participating companies and work performance. More, results are given regarding contribution of selected SMs to the total core damage frequency decreasing.(author)

  16. Focus on safety : a comparative analysis of pipeline safety performance 2000-2002

    International Nuclear Information System (INIS)

    2004-01-01

    Canada's National Energy Board (NEB) is responsible for the promotion of safety, environmental protection and economic efficiency in the Canadian public interest in regulating the design, construction, operation and abandonment of interprovincial and international pipelines within Canada. This second annual report provides a review of the safety performance of oil and gas pipeline companies that are regulated by the NEB. The data used to prepare this report originates from two sources: incident reports submitted under the Onshore Pipeline Regulations, 1999, and from information voluntarily provided by pipeline companies under the Safety Performance Indicators (SPI) initiative. Data comparisons with external reference organizations were included. Six key indicators have been identified to provide comprehensive measures of safety performance for pipeline companies: fatalities, ruptures, injury frequencies, liquid releases, gas releases, and unauthorized activities on the right of way. The safety performance of the federally regulated pipeline industry within Canada was satisfactory during this reporting period (2000-2002). The contractor injury frequency rates reported in 2002 were lower than those reported in 2001, and exhibited more consistency with the levels reported in 2000. The NEB is of the opinion that the elevated number of liquid hydrocarbon spills reported in 2000 were a result of elevated construction levels. No fatalities were reported. There was an increase to three from two in the number of ruptures, due in large part to metal loss (corrosion) and cracking, and external interference (third party damage). The number of spills increased to 76 in 2002 from 55 in 2001, which appears to be more in line with industry averages. The volume of hydrocarbon liquid released in 2002 represented one third the volume released in 2001. refs., 5 tabs., 14 figs

  17. Safety and efficacy of superior rectal artery embolization with particles and metallic coils for the treatment of hemorrhoids (Emborrhoid technique).

    Science.gov (United States)

    Zakharchenko, A; Kaitoukov, Y; Vinnik, Y; Tradi, F; Sapoval, M; Sielezneff, I; Galkin, E; Vidal, V

    2016-11-01

    The purpose of this study was to comprehensively evaluate the short-term outcomes after percutaneous embolization of the superior rectal artery (SRA) with metallic coils and particles for the management of hemorrhoids. Forty patients (15 men, 25 women) with a mean age of 35±5 years (SD) (range: 25-65 years) were prospectively enrolled. All patients had symptomatic hemorrhoids. The distribution of internal hemorrhoids was as follows: grade I (n=6, 16%); grade II (n=28, 69%) and grade III (n=6; 15%). All patients had percutaneous embolization of the SRA with metallic coils and synthetic polyvinyl alcohol particles. Follow-up evaluation included clinical examination, rectoscopy, histopathological analysis of rectal mucosa, duplex Doppler blood flow quantification, electromyography, sphincterometry of the anal sphincter and analysis of patient satisfaction. No immediate complications were observed and no patients had anal pain syndrome after embolization. Hemorrhoids showed a 43% size reduction after embolization (Phemorrhoids and 32/34 patients (94%) with grades I-II hemorrhoids. One month after embolization, anal sphincter contractility normalized and no changes in anal electromyography were observed. Blood flow in the hemorrhoidal plexus dropped from 109±1.2ml/min/100g (SD) before treatment to 60.2±4.4ml/min/100g (SD) (Phemorrhoids. Short-term results with regard to symptom management for hemorrhoidal disease are very encouraging and should stimulate further prospective and multicenter studies. Copyright © 2016 Editions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  18. The IEA Large Coil Task

    International Nuclear Information System (INIS)

    Beard, D.S.; Klose, W.; Shimamoto, S.; Vecsey, G.

    1988-01-01

    A multinational program of cooperative research, development, demonstrations, and exchanges of information on superconducting magnets for fusion was initiated in 1977 under an IEA agreement. The first major step in the development of TF magnets was called the Large Coil Task. Participants in LCT were the U.S. DOE, EURATOM, JAERI, and the Departement Federal de l'Interieur of Switzerland. The goals of LCT were to obtain experimental data, to demonstrate reliable operation of large superconducting coils, and to prove design principles and fabrication techniques being considered for the toroidal magnets of thermonuclear reactors. These goals were to be accomplished through coordinated but largely independent design, development, and construction of six test coils, followed by collaborative testing in a compact toroidal test array at fields of 8 T and higher. Under the terms of the IEA Agreement, the United States built and operated the test facility at Oak Ridge and provided three test coils. The other participants provided one coil each. Information on design and manufacturing and all test data were shared by all. The LCT team of each participant included a government laboratory and industrial partners or contractors. The last coil was completed in 1985, and the test assembly was completed in October of that year. Over the next 23 months, the six-coil array was cooled down and extensive testing was performed. Results were gratifying, as tests achieved design-point performance and well beyond. (Each coil reached a peak field of 9 T.) Experiments elucidated coil behavior, delineated limits of operability, and demonstrated coil safety. (orig./KP)

  19. Restrictive mechanism for safety behaviors and safety attitudes. An analysis focusing on confidence in skills and knowledge

    International Nuclear Information System (INIS)

    Fujita, Tomohiro

    2017-01-01

    This paper investigates the relationship between confidence in skills and knowledge, and safety behaviors and safety attitudes in industrial organizations. According to previous studies, the influence of individual factors such as confidence in skills and knowledge about safety behaviors and attitudes is not as large as that of organizational factors such as leadership and open communication. However, it is possible that having more skills and knowledge contributes to giving workers a better ability to identify perceived hidden risks leading to injuries and accidents in industrial organizations than among those who have fewer skills and less knowledge. Therefore, this study carried out surveys in 2015 and 2016 targeting workers in the energy industry, and reconsidered the relationship between them by adding unexplored factors such as age and work motivations to the existing model. Multivariate analysis revealed that confidence in skills and knowledge have a negative impact on safety behaviors and attitudes, and aging and work motivations have a positive impact on confidence in skills and knowledge. Then, these results suggest that confidence in skills and knowledge which increases along with aging has a restrictive mechanism for safety behaviors and attitudes. Future studies should cover multidimensional aspects of skills and knowledge and focus on the complex relationship between an organization and groups and individuals in the organization. (author)

  20. Building on the Past - Looking to the Future: A Focus on Payload Safety

    Science.gov (United States)

    Nash, Sally K.; Rehm, Raymond B.; Samtoagp. Darren M.; Wong, Teresa K.; Wolf, Scott L.

    2008-01-01

    The history of the space industry stretches far and above lunar landings to the construction of the International Space Station. For years, humans have sought to understand the nature of the universe. As society grows in knowledge and curiosity of space, the focus of maintaining the safety of the crew and vehicle habitability is of utmost importance to the National Aeronautics and Space Administration (NASA) community. Through the years, Payload Safety has developed not only as a Panel, but also as part of the NASA community, striving to enhance the efficiency and understanding of how business should be conducted as more International Partners become involved. This is the first in a series of papers and presentations in what is hoped to be an annual update that provides continuous challenges and lessons learned in the areas of communication, safety requirements and processes and other areas which have been vital to the Payload Safety Review Panel (PSRP).

  1. RF safety assessment of a bilateral four-channel transmit/receive 7 Tesla breast coil: SAR versus tissue temperature limits.

    Science.gov (United States)

    Fiedler, Thomas M; Ladd, Mark E; Bitz, Andreas K

    2017-01-01

    The purpose of this work was to perform an RF safety evaluation for a bilateral four-channel transmit/receive breast coil and to determine the maximum permissible input power for which RF exposure of the subject stays within recommended limits. The safety evaluation was done based on SAR as well as on temperature simulations. In comparison to SAR, temperature is more directly correlated with tissue damage, which allows a more precise safety assessment. The temperature simulations were performed by applying three different blood perfusion models as well as two different ambient temperatures. The goal was to evaluate whether the SAR and temperature distributions correlate inside the human body and whether SAR or temperature is more conservative with respect to the limits specified by the IEC. A simulation model was constructed including coil housing and MR environment. Lumped elements and feed networks were modeled by a network co-simulation. The model was validated by comparison of S-parameters and B 1 + maps obtained in an anatomical phantom. Three numerical body models were generated based on 3 Tesla MRI images to conform to the coil housing. SAR calculations were performed and the maximal permissible input power was calculated based on IEC guidelines. Temperature simulations were performed based on the Pennes bioheat equation with the power absorption from the RF simulations as heat source. The blood perfusion was modeled as constant to reflect impaired patients as well as with a linear and exponential temperature-dependent increase to reflect two possible models for healthy subjects. Two ambient temperatures were considered to account for cooling effects from the environment. The simulation model was validated with a mean deviation of 3% between measurement and simulation results. The highest 10 g-averaged SAR was found in lung and muscle tissue on the right side of the upper torso. The maximum permissible input power was calculated to be 17 W. The

  2. Superior MR images with electronically tuned and decoupled surface coils

    International Nuclear Information System (INIS)

    Ingwersen, H.; Freisen, L.; Friedrich, A.; Kess, H.; Krause, N.; Meissner, R.; Popp, W.

    1987-01-01

    In order to gain free positioning of surface coils in linearly polarized transmitting coils, it is absolutely necessary to electronically decouple both coils. For circularly polarized transmitting coils, decoupling is necessary in any case. In addition to the decoupling circuit automatic electronic tuning of the surface coils is used to gain the bast ratio of signal to noise. This combination of electronically decoupling and tuning of the surface coils yields intrinsic patient safety concerning local power deposition as well as free positioning and easy handling at the same time. Block diagrams, circuit schemes, and MR images obtained with several different surface coils are shown

  3. Focusing on patient safety in the Neonatal Intensive Care Unit environment

    Directory of Open Access Journals (Sweden)

    Ilias Chatziioannidis

    2017-02-01

    Full Text Available Patient safety in the Neonatal Intensive Care Unit (NICU environment is an under-researched area, but recently seems to get high priority on the healthcare quality agenda worldwide. NICU, as a highly sensitive and technological driven environment, signals the importance for awareness in causation of mistakes and accidents. Adverse events and near misses that comprise the majority of human errors, cause morbidity often with devastating results, even death. Likewise in other organizations, errors causes are multiple and complex. Other high reliability organizations, such as air force and nuclear industry, offer examples of how standardized/homogenized work and removal of systems weaknesses can minimize errors. It is widely accepted that medical errors can be explained based on personal and/or system approach. The impact/effect of medical errors can be reduced when thorough/causative identification approach is followed by detailed analysis of consequences and prevention measures. NICU’s medical and nursing staff should be familiar with patient safety language, implement best practices, and support safety culture, maximizing efforts for reducing errors. Furthermore, top management commitment and support in developing patient safety culture is essential in order to assure the achievement of the desirable organizational safety outcomes. The aim of the paper is to review patient safety issues in the NICU environment, focusing on development and implementation of strategies, enhancing high quality standards for health care.

  4. The LVIS Jr. microstent to assist coil embolization of wide-neck intracranial aneurysms: clinical study to assess safety and efficacy

    International Nuclear Information System (INIS)

    Moehlenbruch, M.; Herweh, C.; Behrens, L.; Jestaedt, L.; Bendszus, M.; Pham, M.; Amiri, H.; Ringleb, P.A.

    2014-01-01

    This study was aimed to assess clinical safety and efficacy of the LVIS Jr. microstent in stent-assisted coil embolization of wide-neck intracranial aneurysms. IRB approved single-center interventional clinical study in 22 patients (10 females, 12 males, mean age 55, age range 33-74 years) for the endovascular treatment of wide-neck aneurysms. After obtaining informed consent, patients were included according to the following criteria: aneurysm fundus-to-neck ratio 4 mm, and a parent vessel diameter of ≤3.5 mm. Primary end point for clinical safety was absence of death, absence of major or minor stroke, and absence of transient ischemic attack. Primary end point for treatment efficacy was complete angiographic occlusion according to the Raymond-Roy Occlusion Classification (RROC) immediately after the procedure and at follow-up after 3 and 6 months on magnetic resonance imaging (MRI). In 20/22 (91 %) of patients, the primary end point of safety was reached; in the two remaining patients, transient ischemic attack, but no permanent deficit was observed; in 16/22 (73 %), efficient occlusion (RROC1) was reached, and in 6/22 (27 %), a residual neck remained (RROC2). Single [seven with antegrade, two in crossover configuration, and four with ''first-balloon-then-stent'' (FBTS) technique] or double-stent (eight patients with Y configuration and one patient with X configuration) deployment was technically successful in all cases. Deployment of the LVIS Jr. microstent in various single- or double-stent configurations is safe and effective to assist the treatment of intracranial wide-neck aneurysms. (orig.)

  5. "Nursing Students Assaulted": Considering Student Safety in Community-Focused Experiences.

    Science.gov (United States)

    Maneval, Rhonda E; Kurz, Jane

    2016-01-01

    Community nursing experiences for undergraduate students have progressed beyond community-based home visits to a wide array of community-focused experiences in neighborhood-based centers, clinics, shelters, and schools. Our Bachelor of Science in Nursing program chose to use sites situated within neighborhoods close to campus in order to promote student and faculty engagement in the local community. These neighborhood sites provide opportunities for students to deliver nursing services to underserved and vulnerable populations experiencing poverty and health disparities. Some of these neighborhoods are designated as high crime areas that may potentially increase the risk of harm to students and faculty. There is a need to acknowledge the risk to personal safety and to proactively create policies and guidelines to reduce potential harm to students engaged in community-focused experiences. When a group of baccalaureate nursing students was assaulted while walking to a neighborhood clinic, the faculty was challenged as how to respond given the lack of policies and guidelines. Through our experience, we share strategies to promote personal safety for students and recommend transparency by administrators regarding potential safety risks to students engaged in community-focused fieldwork activities. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. A report on developing a checklist to assess company plans focused on improving safety awareness, safe behaviour and safety culture: final report

    NARCIS (Netherlands)

    Steijger, N.; Starren, H.; Keus, M.; Gort, J.; Vervoort, M.

    2003-01-01

    This report describes the process of developing a checklist to asses company plans focused on improving safety awareness, safe behaviour and safety culture. These plans are part of a programme initiated by the Ministry of Social Affairs and Employment aiming at improving the safety performance of

  7. Conception of Brownian coil

    OpenAIRE

    Zhang, Jiayuan

    2018-01-01

    This article proposes a conception of Brownian coil. Brownian coil is a tiny coil with the same size of pollen. Once immersed into designed magnetic field and liquid, the coil will be moved and deformed macroscopically, due to the microscopic thermodynamic molecular collisions. Such deformation and movement will change the magnetic flux through the coil, by which an ElectroMotive Force (EMF) is produced. In this work, Brownian heat exchanger and Brownian generator are further designed to tran...

  8. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  9. Overview of IRSN R and D on NPP safety, with focus on severe accident

    International Nuclear Information System (INIS)

    Van Dorsselaere, Jean-Pierre

    2015-01-01

    IRSN contributes to the continuous improvement of safety level of Gen.II and III reactors, with the aim to approach for Gen.II the target safety level of Gen.III. This needs to build the necessary knowledge to appreciate margins for safety important systems, structures and components in the frame of plant operation life extension beyond 40 years. Research is a major IRSN mission that is tightly linked to expertise needs: it involves 40% of overall budget and, out of radiation protection and safety of waste disposal, around 280 scientists. IRSN has acquired a huge experience in the last 30 years on severe accidents, both on experimental and theoretical aspects, in particular through management of large international research programmes like the Phébus. FP integral experiments in the last 20 years and the coordination of the SARNET network of excellence that continues now in the frame of the NUGENIA European association. Besides, IRSN is developing, in collaboration with GRS (Germany), the integral system code ASTEC that is considered now as the European reference code due to the continuous capitalization of all the international knowledge. The presentation summarizes the ongoing IRSN research on the different phenomena involved in severe accidents, with more focus in the last years on mitigation devices or measures, i.e. for in-vessel and ex-vessel corium coolability, hydrogen explosion risk and source term. IRSN leads several international projects in Euratom frame (such as CESAM on ASTEC, PASSAM on source term mitigation, and IVMR on in-vessel corium retention) or OECD/NEA/CSNI (such as STEM). Moreover, several national projects on the above issues are ongoing with the French actors in this domain. Collaboration between IRSN and India is very active and efficient on ASTEC code with BARC and AERB, in particular through PHWR model development and assessment, and could be extended in the future to other issues either on severe accidents or on other Topics. (author)

  10. High Retention and Safety of Percutaneously Implanted Endovascular Embolization Coils as Fiducial Markers for Image-Guided Stereotactic Ablative Radiotherapy of Pulmonary Tumors

    International Nuclear Information System (INIS)

    Hong, Julian C.; Yu Yao; Rao, Aarti K.; Dieterich, Sonja; Maxim, Peter G.; Le, Quynh-Thu; Diehn, Maximilian; Sze, Daniel Y.; Kothary, Nishita; Loo, Billy W.

    2011-01-01

    Purpose: To compare the retention rates of two types of implanted fiducial markers for stereotactic ablative radiotherapy (SABR) of pulmonary tumors, smooth cylindrical gold 'seed' markers ('seeds') and platinum endovascular embolization coils ('coils'), and to compare the complication rates associated with the respective implantation procedures. Methods and Materials: We retrospectively analyzed the retention of percutaneously implanted markers in 54 consecutive patients between January 2004 and June 2009. A total of 270 markers (129 seeds, 141 coils) were implanted in or around 60 pulmonary tumors over 59 procedures. Markers were implanted using a percutaneous approach under computed tomography (CT) guidance. Postimplantation and follow-up imaging studies were analyzed to score marker retention relative to the number of markers implanted. Markers remaining near the tumor were scored as retained. Markers in a distant location (e.g., pleural space) were scored as lost. CT imaging artifacts near markers were quantified on radiation therapy planning scans. Results: Immediately after implantation, 140 of 141 coils (99.3%) were retained, compared to 110 of 129 seeds (85.3%); the difference was highly significant (p < 0.0001). Of the total number of lost markers, 45% were reported lost during implantation, but 55% were lost immediately afterwards. No additional markers were lost on longer-term follow-up. Implanted lesions were peripherally located for both seeds (mean distance, 0.33 cm from pleural surface) and coils (0.34 cm) (p = 0.96). Incidences of all pneumothorax (including asymptomatic) and pneumothorax requiring chest tube placement were lower in implantation of coils (23% and 3%, respectively) vs. seeds (54% and 29%, respectively; p = 0.02 and 0.01). The degree of CT artifact was similar between marker types. Conclusions: Retention of CT-guided percutaneously implanted coils is significantly better than that of seed markers. Furthermore, implanting coils is at

  11. Radiation Safety Management Guidelines for PET-CT: Focus on Behavior and Environment

    International Nuclear Information System (INIS)

    Jung, Jin Wook; Han, Eun Ok

    2011-01-01

    Our purpose is to specify behavior and environmental factors aimed at reducing the exposed dosage caused by PET-CT and to develop radiation safety management guidelines adequate for domestic circumstances. We have used a multistep-multimethod as the methodological approach to design and to carry out the research both in quality and quantity, including an analysis on previous studies, professional consultations and a survey. The survey includes responses from 139 practitioners in charged of 109 PET-CTs installed throughout Korea(reported by the Korean Society of Nuclear Medicine, 2010). The research use 156 questions using Cronbach's α (alpha) coefficients which were: 0.818 for 'the necessity of setting and installing the radiation protective environment'; 0.916 for 'the necessity of radiation protection', 'setting and installing the radiation protective environment'; and 0.885 for 'radiation protection'. The check list, derived from the radiation safety management guidelines focused on behavior and environment, was composed of 20 items for the radiation protective environment: including 5 items for the patient; 4 items for the guardian; 3 items for the radiologist; and 8 items applied to everyone involved; for a total of 26 items for the radiation protective behavior including: 12 items for the patient; 1 item for the guardian, 7 items for the radiologist; and 6 items applied to everyone involved. The specific check list is shown in (Table 5-6). Since our country has no safety management guidelines of its own to reduce the exposed dosage caused by PET-CTs, we believe the guidelines developed through this study means great deal to the field as it is not only appropriate for domestic circumstances, but also contains specific check lists for each target who may be exposed to radiation in regards to behavior and environment.

  12. A history of detachable coils: 1987-2012.

    Science.gov (United States)

    Hui, Ferdinand K; Fiorella, David; Masaryk, Thomas J; Rasmussen, Peter A; Dion, Jacques E

    2014-03-01

    The development of detachable coils is one of the most pivotal developments in neurointervention, providing a tool that could be used to treat a wide variety of hemorrhagic stroke. From the original Guglielmi detachable coil, a number of different coil designs and delivery designs have evolved. This article reviews the history of commercially available detachable coils. A timeline of detachable coils was constructed and coil design philosophies were reviewed. A complete list of commercially available coils is presented in a timeline format. Detachable coil technology continues to evolve. Advances in construction and design have yielded products which may benefit patients in terms of safety, radiation dose reduction and cost of treatment. Continued evolution is expected, irrespective of competing disruptive technologies.

  13. Superconducting coil design for a tokamak experimental power reactor

    International Nuclear Information System (INIS)

    Turner, L.R.; Wang, S.T.; Smelser, P.

    1977-01-01

    Superconducting toroidal field (TF) and polodial-field (PF) coils have been designed for the proposed Argonne National Laboratory experimental power reactor (EPR). Features of the design include: (1) Peak field of 8 T at 4.2 K or 10 T at 3.0 K. (2) Constant-tension shape for the TF coils, corrected for the finite number (16) of coils. (3) Analysis of errors in coil alignment. (4) Comparison of safety aspects of series-connected and parallel-connected coils. (5) A 60 kA sheet conductor of NbTi with copper stabilizer and stainless steel for support. (6) Superconducting PF coils outside the TF coils. (7) The TF coils shielded from pulsed fields by high-purity aluminum

  14. The perception of injury risk and safety in triathlon competition: an exploratory focus group study.

    Science.gov (United States)

    Gosling, Cameron McR; Donaldson, Alex; Forbes, Andrew B; Gabbe, Belinda J

    2013-01-01

    To explore stakeholder perceptions of triathlon competition safety and injury risk. Qualitative focus group study. Triathlon stakeholders from Melbourne, Australia. Competition organizers, coaches, and competitors of various skill levels, age, gender, and experience (n = 18). Focus groups were conducted, recorded, and transcribed for analysis. Key themes were identified using content analysis. The perceived risk of serious injury was highest for cycling. Running was most commonly linked to minor injuries. Physical and environmental factors, including course turning points, funneling of competitors into narrow sections, and the weather, were perceived as contributing to injury. Experience, skill level, feelings of vulnerability, personal awareness, club culture, and gender issues were perceived as the competitor-related factors potentially contributing to injury. The cycling mount/dismount area, cycling, and swim legs were the race sections perceived as the riskiest for competitors. Competition organizers were considered to generally have the competitors' best interest as a priority. Triathlons were acknowledged as risky activities and individual competitors accepted this risk. This study has highlighted the main risks and concerns perceived by triathlon competitors, coaches, and competition organizers, which will help identify potential, context-relevant intervention strategies to reduce injury risk.

  15. Water cooling coil

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, S; Ito, Y; Kazawa, Y

    1975-02-05

    Object: To provide a water cooling coil in a toroidal nuclear fusion device, in which coil is formed into a small-size in section so as not to increase dimensions, weight or the like of machineries including the coil. Structure: A conductor arranged as an outermost layer of a multiple-wind water cooling coil comprises a hollow conductor, which is directly cooled by fluid, and as a consequence, a solid conductor disposed interiorly thereof is cooled indirectly.

  16. NCSX Trim Coil Design

    International Nuclear Information System (INIS)

    Kalish, M.; Brooks, A.; Rushinski, J.; Upcavage, R.

    2009-01-01

    The National Compact Stellarator Experiment (NCSX) was being constructed at the Princeton Plasma Physics Laboratory in partnership with Oak Ridge National Laboratory before work was stopped in 2008. The objective of this experiment was to develop the stellarator concept and evaluate it's potential as a model for future fusion power plants. Stellarator design requires very precisely positioned Modular Coils of complex shape to form 3D plasmas. In the design of NCSX, Trim Coils were required to compensate for both the positioning of the coils during assembly and the fabrication tolerances of the Modular Coils. Use of the Trim Coils allowed for larger tolerances increasing ease of assembly and decreasing overall cost. A set of Trim coils was developed to suppress the toroidal flux in island regions due to misalignment, magnetic materials, and eddy currents. The requirement imposed upon the design forced the toroidal flux in island regions below 10% of the total toroidal flux in the plasma. An analysis was first performed to evaluate candidate Trim Coil configurations iterating both the size, number, and position of the coils. The design was optimized considering both performance and cost while staying within the tight restraints presented by the space limited geometry. The final design of the Trim Coils incorporated a 48 Coil top bottom symmetric set. Fabrication costs were minimized by having only two coil types and using a planar conventional design with off the shelf commercial conductor. The Trim Coil design incorporated supports made from simple structural shapes assembled together in a way which allowed for adjustment as well as accommodation for the tolerance build up on the mating surfaces. This paper will summarize the analysis that led to the optimization of the Trim Coils set, the trim coil mechanical design, thermal and stress analysis, and the design of the supporting Trim Coil structure

  17. Exploring road design factors influencing tram road safety - Melbourne tram driver focus groups.

    Science.gov (United States)

    Naznin, Farhana; Currie, Graham; Logan, David

    2018-01-01

    Melbourne, Australia has the largest tram/streetcar network in the world including the largest mixed traffic tram operating environment. Therefore, Melbourne tram drivers are responsible for controlling one of the heaviest vehicles on road ranging from shared tram lanes to exclusive tram lanes. In addition to different tram lane configurations, tram drivers need to follow different traffic signal phases at intersections including tram priority signals as well as need to serve passengers at various types of closely spaced tram stops. Despite all these challenges, no research has explored tram driver perceptions of the risk factors on different tram route road design configurations. Therefore, the aim of this study is to investigate how tram drivers' safety perceptions alter along various tram route sections, signal settings and stop configurations. A tram driver focus group approach was adopted for this research involving thirty tram drivers (4 female and 26 male drivers). The tram drivers' age ranged from 29 to 63 years, with an average age of 47.6 years (standard deviation of 10.1 years), and their experience of tram driving ranged from 1.17 to 31 years, with an average experience of 12.5 years (standard deviation of 10.2 years). The participating tram drivers perceived that the raised tram tracks and tramways with raised yellow curbing beside tracks are safer lane priority features on the Melbourne tram network compared to full-time, part-time and mixed traffic tram lanes. They regarded 'hook turns' as a safe form of tram signal priority treatment at intersections and platform tram stops as the safest tram stop design for all passengers among all other tram stop designs in Melbourne. Findings of this research could enhance the understanding of crash risk factors for different tram route features and thus can offer effective planning strategies for transit agencies to improve tram road safety. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Dual coil ignition system

    Energy Technology Data Exchange (ETDEWEB)

    Huberts, Garlan J.; Qu, Qiuping; Czekala, Michael Damian

    2017-03-28

    A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding.

  19. Biomaterials Made from Coiled-Coil Peptides.

    Science.gov (United States)

    Conticello, Vincent; Hughes, Spencer; Modlin, Charles

    The development of biomaterials designed for specific applications is an important objective in personalized medicine. While the breadth and prominence of biomaterials have increased exponentially over the past decades, critical challenges remain to be addressed, particularly in the development of biomaterials that exhibit highly specific functions. These functional properties are often encoded within the molecular structure of the component molecules. Proteins, as a consequence of their structural specificity, represent useful substrates for the construction of functional biomaterials through rational design. This chapter provides an in-depth survey of biomaterials constructed from coiled-coils, one of the best-understood protein structural motifs. We discuss the utility of this structurally diverse and functionally tunable class of proteins for the creation of novel biomaterials. This discussion illustrates the progress that has been made in the development of coiled-coil biomaterials by showcasing studies that bridge the gap between the academic science and potential technological impact.

  20. Novel transcranial magnetic stimulation coil for mice

    Science.gov (United States)

    March, Stephen; Stark, Spencer; Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) shows potential for non-invasive treatment of various neurological disorders. Significant work has been performed on the design of coils used for TMS on human subjects but few reports have been made on the design of coils for use on the brains of animals such as mice. This work is needed as TMS studies utilizing mice can allow rapid preclinical development of TMS for human disorders but the coil designs developed for use on humans are inadequate for optimal stimulation of the much smaller mouse brain. A novel TMS coil has been developed with the goal of inducing strong and focused electric fields for the stimulation of small animals such as mice. Calculations of induced electric fields were performed utilizing an MRI derived inhomogeneous model of an adult male mouse. Mechanical and thermal analysis of this new TMS helmet-coil design have also been performed at anticipated TMS operating conditions to ensure mechanical stability of the new coil and establish expected linear attraction and rotational force values. Calculated temperature increases for typical stimulation periods indicate the helmet-coil system is capable of operating within established medical standards. A prototype of the coil has been fabricated and characterization results are presented.

  1. Improving patient safety: patient-focused, high-reliability team training.

    Science.gov (United States)

    McKeon, Leslie M; Cunningham, Patricia D; Oswaks, Jill S Detty

    2009-01-01

    Healthcare systems are recognizing "human factor" flaws that result in adverse outcomes. Nurses work around system failures, although increasing healthcare complexity makes this harder to do without risk of error. Aviation and military organizations achieve ultrasafe outcomes through high-reliability practice. We describe how reliability principles were used to teach nurses to improve patient safety at the front line of care. Outcomes include safety-oriented, teamwork communication competency; reflections on safety culture and clinical leadership are discussed.

  2. Evaluation of focused multipolar stimulation for cochlear implants: a preclinical safety study

    Science.gov (United States)

    Shepherd, Robert K.; Wise, Andrew K.; Enke, Ya Lang; Carter, Paul M.; Fallon, James B.

    2017-08-01

    Objective. Cochlear implants (CIs) have a limited number of independent stimulation channels due to the highly conductive nature of the fluid-filled cochlea. Attempts to develop highly focused stimulation to improve speech perception in CI users includes the use of simultaneous stimulation via multiple current sources. Focused multipolar (FMP) stimulation is an example of this approach and has been shown to reduce interaction between stimulating channels. However, compared with conventional biphasic current pulses generated from a single current source, FMP is a complex stimulus that includes extended periods of stimulation before charge recovery is achieved, raising questions on whether chronic stimulation with this strategy is safe. The present study evaluated the long-term safety of intracochlear stimulation using FMP in a preclinical animal model of profound deafness. Approach. Six cats were bilaterally implanted with scala tympani electrode arrays two months after deafening, and received continuous unilateral FMP stimulation at levels that evoked a behavioural response for periods of up to 182 d. Electrode impedance, electrically-evoked compound action potentials (ECAPs) and auditory brainstem responses (EABRs) were monitored periodically over the course of the stimulation program from both the stimulated and contralateral control cochleae. On completion of the stimulation program cochleae were examined histologically and the electrode arrays were evaluated for evidence of platinum (Pt) corrosion. Main results. There was no significant difference in electrode impedance between control and chronically stimulated electrodes following long-term FMP stimulation. Moreover, there was no significant difference between ECAP and EABR thresholds evoked from control or stimulated cochleae at either the onset of stimulation or at completion of the stimulation program. Chronic FMP stimulation had no effect on spiral ganglion neuron (SGN) survival when compared with

  3. Epidemiology of occupational injuries by nationality in Qatar: Evidence for focused occupational safety programmes.

    Science.gov (United States)

    Al-Thani, Hassan; El-Menyar, Ayman; Consunji, Rafael; Mekkodathil, Ahammed; Peralta, Ruben; Allen, Katharine A; Hyder, Adnan A

    2015-09-01

    Occupational injuries are the second leading cause of trauma admission in Qatar. Given the wide diversity of the country's migrant worker populations at risk, this study aimed to analyse and describe the epidemiology of these injuries based on the workers nationality residing in Qatar. A retrospective analysis of trauma registry data on occupational-related injuries was conducted. The analysis included all patients [aged ≥18 years] admitted to the Level I Hamad Trauma Center, from January 1, 2010 to December 31, 2013. Out of 6555 trauma admissions, 2015 (30.7%) patients had occupational injury. The admitted Case Fatality Rate (CFR) was 4.3 per 100 occupational injury related trauma admissions. Overall non-fatal occupational injury rate was 37.34 per 100,000 workers, whereas fatal injury rate was 1.58 per 100,000 workers. Most of the workers experiencing occupational injuries were from Nepal (28%), India (20%) and Bangladesh (9%). Fatal occupational injuries were predominately among Indians (20%), Nepalese (19%), and Filipinos/Bangladeshis (both 8%). Filipinos had the highest admitted CFR at 8.2 deaths per 100 trauma admissions with the next highest being Indians and Indonesians (4.2 per 100 trauma admissions). During the study period, the incidence of severe occupational injuries decreased despite a simultaneous increase in the worker population within Qatar. Almost one in four occupational injuries was a major trauma (ISS≥16). Nepalese and Indian workers represented 29% and 18% of all major trauma cases. Non-fatal occupational injuries appear to follow a pattern distinct from fatal ones. High-risk worker populations as defined by those with high admitted CFRs, experiencing the most severe or fatal injuries, must be the focus of targeted risk factor analysis and occupational safety interventions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Superconducting magnetic coil

    Science.gov (United States)

    Aized, Dawood; Schwall, Robert E.

    1996-06-11

    A superconducting magnetic coil includes a plurality of sections positioned axially along the longitudinal axis of the coil, each section being formed of an anisotropic high temperature superconductor material wound about a longitudinal axis of the coil and having an associated critical current value that is dependent on the orientation of the magnetic field of the coil. The cross section of the superconductor, or the type of superconductor material, at sections along the axial and radial axes of the coil are changed to provide an increased critical current at those regions where the magnetic field is oriented more perpendicularly to the conductor plane, to thereby increase the critical current at these regions and to maintain an overall higher critical current of the coil.

  5. Cooling and dehumidifying coils

    International Nuclear Information System (INIS)

    Murthy, M.V.K.

    1988-01-01

    The operating features of cooling and dehumidifying coils and their constructional details are discussed. The heat transfer relations as applicable to the boiling refrigerant and a single phase fluid are presented. Methods of accounting for the effect of moisture condensation on the air side heat transfer coefficient and the fin effectiveness are explained. The logic flow necessary to analyze direct expansion coils and chilled water coils is discussed

  6. The JET divertor coil

    International Nuclear Information System (INIS)

    Last, J.R.; Froger, C.; Sborchia, C.

    1989-01-01

    The divertor coil is mounted inside the Jet vacuum vessel and is able to carry 1 MA turns. It is of conventional construction - water cooled copper, epoxy glass insulation -and is contained in a thin stainless steel case. The coil has to be assembled, insulated and encased inside the Jet vacuum vessel. A description of the coil is given, together with technical information (including mechanical effects on the vacuum vessel), an outline of the manufacture process and a time schedule. (author)

  7. FOCUS: the Society of Cardiovascular Anesthesiologists' initiative to improve quality and safety in the cardiovascular operating room.

    Science.gov (United States)

    Barbeito, Atilio; Lau, William Travis; Weitzel, Nathaen; Abernathy, James H; Wahr, Joyce; Mark, Jonathan B

    2014-10-01

    The Society of Cardiovascular Anesthesiologists (SCA) introduced the FOCUS initiative (Flawless Operative Cardiovascular Unified Systems) in 2005 in response to the need for a rigorous scientific approach to improve quality and safety in the cardiovascular operating room (CVOR). The goal of the project, which is supported by the SCA Foundation, is to identify hazards and develop evidence-based protocols to improve cardiac surgery safety. A hazard is anything that has the potential to cause a preventable adverse event. Specifically, the strategic plan of FOCUS includes 3 goals: (1) identifying hazards in the CVOR, (2) prioritizing hazards and developing risk-reduction interventions, and (3) disseminating these interventions. Collectively, the FOCUS initiative, through the work of several groups composed of members from different disciplines such as clinical medicine, human factors engineering, industrial psychology, and organizational sociology, has identified and documented significant hazards occurring daily in our CVORs. Some examples of frequent occurrences that contribute to reduce the safety and quality of care provided to cardiac surgery patients include deficiencies in teamwork, poor OR design, incompatible technologies, and failure to adhere to best practices. Several projects are currently under way that are aimed at better understanding these hazards and developing interventions to mitigate them. The SCA, through the FOCUS initiative, has begun this journey of science-driven improvement in quality and safety. There is a long and arduous road ahead, but one we need to continue to travel.

  8. A large waterborne outbreak of campylobacteriosis in Norway: The need to focus on distribution system safety

    Directory of Open Access Journals (Sweden)

    Lund Helge

    2008-09-01

    of water distribution systems. Good quality source water alone is not enough to ensure water safety. For a better risk management, more focus should be put on the distribution system security. Waterworks personnel should monitor the pressure regularly; reduce the leakage by upgrading the distribution network and use chlorination when conducting maintenance work.

  9. Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness

    Directory of Open Access Journals (Sweden)

    Smijs TG

    2011-10-01

    Full Text Available Threes G Smijs1–3, Stanislav Pavel4 1Faculty of Science, Open University in The Netherlands, Rotterdam, The Netherlands; 2University of Leiden, Leiden Amsterdam Center for Drug Research, Leiden, The Netherlands; 3Erasmus MC, Center for Optical Diagnostics and Therapy, Rotterdam, The Netherlands; 4Charles University, Faculty of Medicine, Department of Dermatology, Pilsen, Czech Republic Abstract: Sunscreens are used to provide protection against adverse effects of ultraviolet (UVB (290–320 nm and UVA (320–400 nm radiation. According to the United States Food and Drug Administration, the protection factor against UVA should be at least one-third of the overall sun protection factor. Titanium dioxide (TiO2 and zinc oxide (ZnO minerals are frequently employed in sunscreens as inorganic physical sun blockers. As TiO2 is more effective in UVB and ZnO in the UVA range, the combination of these particles assures a broad-band UV protection. However, to solve the cosmetic drawback of these opaque sunscreens, microsized TiO2 and ZnO have been increasingly replaced by TiO2 and ZnO nanoparticles (NPs (<100 nm. This review focuses on significant effects on the UV attenuation of sunscreens when microsized TiO2 and ZnO particles are replaced by NPs and evaluates physicochemical aspects that affect effectiveness and safety of NP sunscreens. With the use of TiO2 and ZnO NPs, the undesired opaqueness disappears but the required balance between UVA and UVB protection can be altered. Utilization of mixtures of micro- and nanosized ZnO dispersions and nanosized TiO2 particles may improve this situation. Skin exposure to NP-containing sunscreens leads to incorporation of TiO2 and ZnO NPs in the stratum corneum, which can alter specific NP attenuation properties due to particle–particle, particle–skin, and skin–particle–light physicochemical interactions. Both sunscreen NPs induce (photocyto- and genotoxicity and have been sporadically observed in viable

  10. Human factors experts beginning to focus on organizational factors in safety.

    Science.gov (United States)

    Westrum, R

    1996-10-01

    The role of organizational culture in aviation safety is explored. Information flow is used to demonstrate three ranges of climate within an organization. Organizations may be pathological in which information is hidden, bureaucratic in which information is ignored, or generative in which information is actively sought. The effects of organizational change on personnel are explored with emphasis on mergers between air carriers. The relationship between safety measures and economic pressures is discussed.

  11. SAFETY

    CERN Multimedia

    M. Plagge, C. Schaefer and N. Dupont

    2013-01-01

    Fire Safety – Essential for a particle detector The CMS detector is a marvel of high technology, one of the most precise particle measurement devices we have built until now. Of course it has to be protected from external and internal incidents like the ones that can occur from fires. Due to the fire load, the permanent availability of oxygen and the presence of various ignition sources mostly based on electricity this has to be addressed. Starting from the beam pipe towards the magnet coil, the detector is protected by flooding it with pure gaseous nitrogen during operation. The outer shell of CMS, namely the yoke and the muon chambers are then covered by an emergency inertion system also based on nitrogen. To ensure maximum fire safety, all materials used comply with the CERN regulations IS 23 and IS 41 with only a few exceptions. Every piece of the 30-tonne polyethylene shielding is high-density material, borated, boxed within steel and coated with intumescent (a paint that creates a thick co...

  12. Focus on the studies in support of fire safety analysis. IRSN modelling approach for nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    Espargilliere, Julien; Meyrand, Raphael; Vinot, Thierry [Institut de Radioprotection et de Surete Nucleaire (IRSN), Fontenay-aux-Roses (France)

    2015-12-15

    For a fire safety analysis, in order to comply with nuclear safety goals, a nuclear fuel facility operator has to define the elements important for safety to be maintained, even in the case of a fire. One of the key points of this fire analysis is the assessment of possible fire scenarios in the facility. This paper presents the IRSN method applied to a case study to assess fire scenarios which have the most harmful effects on safety targets. The layout consists in a central room (fire cell) containing three glove boxes with radioactive material and three electrical cabinets. This room is linked to two connecting compartments (the fire cell and these two compartments define the containment cell) and then to two corridors. Each room is equipped with a mechanical ventilation system, and a pressure cascade is established from the corridors to the central room. A fire scenario was studied with fire ignition occurring in an electrical cabinet. This scenario has a set of safety goals (prevention of fire cell and containment device failure, propagation of the fire). This case study was conducted with the IRSN code SYLVIA based on two zones modelling. Safety goals were associated with key parameters and performance criteria to be fulfilled. Modelling assumptions were defined in order to maximize physical effects of the fire. Sensitivity studies were also conducted on key parameters such as oxygen limitation, equivalent-fuel definition. Eventually, a critical analysis of the code models was carried out.

  13. Active internal corrector coils

    International Nuclear Information System (INIS)

    Thompson, P.A.; Cottingham, J.; Dahl, P.

    1986-01-01

    Trim or corrector coils to correct main magnet field errors and provide higher multipole fields for beam optics purposes are a standard feature of superconducting magnet accelerator systems. This paper describes some of the design and construction features of powered internal trim coils and a sampling of the test results obtained

  14. Compact stellarator coils

    International Nuclear Information System (INIS)

    Pomphrey, N.; Berry, L.A.; Boozer, A.H.

    2001-01-01

    Experimental devices to study the physics of high-beta (β>∼4%), low aspect ratio (A<∼4.5) stellarator plasmas require coils that will produce plasmas satisfying a set of physics goals, provide experimental flexibility, and be practical to construct. In the course of designing a flexible coil set for the National Compact Stellarator Experiment, we have made several innovations that may be useful in future stellarator design efforts. These include: the use of Singular Value Decomposition methods for obtaining families of smooth current potentials on distant coil winding surfaces from which low current density solutions may be identified; the use of a Control Matrix Method for identifying which few of the many detailed elements of the stellarator boundary must be targeted if a coil set is to provide fields to control the essential physics of the plasma; the use of Genetic Algorithms for choosing an optimal set of discrete coils from a continuum of potential contours; the evaluation of alternate coil topologies for balancing the tradeoff between physics objective and engineering constraints; the development of a new coil optimization code for designing modular coils, and the identification of a 'natural' basis for describing current sheet distributions. (author)

  15. Liquid rope coiling

    NARCIS (Netherlands)

    Ribe, N.M.; Habibi, M.; Bonn, D.

    2012-01-01

    A thin stream or rope of viscous fluid falling from a sufficient height onto a surface forms a steadily rotating helical coil. Tabletop laboratory experiments in combination with a numerical model for slender liquid ropes reveal that finite-amplitude coiling can occur in four distinct regimes

  16. Pressure rise analysis in superconducting coils during dumping

    International Nuclear Information System (INIS)

    Tada, E.; Shimamoto, S.

    1984-01-01

    This chapter describes the ALPHE computer code, whose purpose is to calculate transient helium behavior in a poolboiling coil and to determine suitable characteristics of safety devices to minimize the maximum pressure and the liquid helium lost during dumping due to quench, or when discharging without normalcy. The analysis is compared with the measurements obtained in the domestic test of the Japanese LCT coil. Topics considered include basic equations (helium behavior, heat generation), manual dump without quench, and dumping due to quench. It is demonstrated that the transient behavior, calculated by ALPHE assuming quasi-static equilibrium between helium and coil, is in good agreement with the experimental measurements observed in the domestic test of the Japanese LCT coil. The engineering technique required for the design criteria of superconducting coils and safety device during dumping is established. ALPHE can be used to design an emergency safety system for a helium refrigerator during dumping

  17. Molecular basis of coiled-coil oligomerization-state specificity.

    Science.gov (United States)

    Ciani, Barbara; Bjelic, Saša; Honnappa, Srinivas; Jawhari, Hatim; Jaussi, Rolf; Payapilly, Aishwarya; Jowitt, Thomas; Steinmetz, Michel O; Kammerer, Richard A

    2010-11-16

    Coiled coils are extensively and successfully used nowadays to rationally design multistranded structures for applications, including basic research, biotechnology, nanotechnology, materials science, and medicine. The wide range of applications as well as the important functions these structures play in almost all biological processes highlight the need for a detailed understanding of the factors that control coiled-coil folding and oligomerization. Here, we address the important and unresolved question why the presence of particular oligomerization-state determinants within a coiled coil does frequently not correlate with its topology. We found an unexpected, general link between coiled-coil oligomerization-state specificity and trigger sequences, elements that are indispensable for coiled-coil formation. By using the archetype coiled-coil domain of the yeast transcriptional activator GCN4 as a model system, we show that well-established trimer-specific oligomerization-state determinants switch the peptide's topology from a dimer to a trimer only when inserted into the trigger sequence. We successfully confirmed our results in two other, unrelated coiled-coil dimers, ATF1 and cortexillin-1. We furthermore show that multiple topology determinants can coexist in the same trigger sequence, revealing a delicate balance of the resulting oligomerization state by position-dependent forces. Our experimental results should significantly improve the prediction of the oligomerization state of coiled coils. They therefore should have major implications for the rational design of coiled coils and consequently many applications using these popular oligomerization domains.

  18. Ergonomic analysis of safety signs: a focus of informational and cultural ergonomics.

    Science.gov (United States)

    Cavalcanti, Janaina; Soares, Marcelo

    2012-01-01

    This paper presents the results of a research carried out in the states of Pernambuco and Rio Grande do Sul, Brazil about differences and similarities in the graphic representation of safety signs at factories of food, steel, shoes and construction/ building industries, together with their workers' opinions on the security signs. The overall results show differences in the sign structure across the states, confirming the influence of cultural differences on the design of safety signs, which must be taken into account during the design process.

  19. Missing focus on Human Factors - organizational and cognitive ergonomics - in the safety management for the petroleum industry.

    Science.gov (United States)

    Johnsen, Stig O; Kilskar, Stine Skaufel; Fossum, Knut Robert

    2017-08-01

    More attention has recently been given to Human Factors in petroleum accident investigations. The Human Factors areas examined in this article are organizational, cognitive and physical ergonomics. A key question to be explored is as follows: To what degree are the petroleum industry and safety authorities in Norway focusing on these Human Factors areas from the design phase? To investigate this, we conducted an innovative exploratory study of the development of four control centres in Norwegian oil and gas industry in collaboration between users, management and Human Factors experts. We also performed a literature survey and discussion with the professional Human Factors network in Norway. We investigated the Human Factors focus, reasons for not considering Human Factors and consequences of missing Human Factors in safety management. The results revealed an immature focus and organization of Human Factors. Expertise on organizational ergonomics and cognitive ergonomics are missing from companies and safety authorities and are poorly prioritized during the development. The easy observable part of Human Factors (i.e. physical ergonomics) is often in focus. Poor focus on Human Factors in the design process creates demanding conditions for human operators and impact safety and resilience. There is lack of non-technical skills such as communication and decision-making. New technical equipment such as Closed Circuit Television is implemented without appropriate use of Human Factors standards. Human Factors expertise should be involved as early as possible in the responsible organizations. Verification and validation of Human Factors should be improved and performed from the start, by certified Human Factors experts in collaboration with the workforce. The authorities should check-back that the regulatory framework of Human Factors is communicated, understood and followed.

  20. Large coil task and results of testing US coils

    International Nuclear Information System (INIS)

    Haubenreich, P.N.

    1986-01-01

    The United States, EURATOM, Japan, and Switzerland have collaborated since 1978 in development of superconducting toroidal field coils for fusion reactor applications. The United States provided a test facility nd three coils; the other participants, one coil each. All coils have the same interface dimensions and performance requirements (stable at 8 T), but internal design was decided by each team. Two US coil teams chose bath-cooled NbTi, 10-kA conductors. One developed a Nb 3 Sn conductor, cooled by internal flow, rated at 18 kA. All US coils have diagnostic instrumentation and imbedded heaters that enable stability tests and simulated nuclear heating experiments. In single-coil tests, each coil operated at full current in self-field (6.4 T). In six-coil tests that began in July 1986, one US coil and the Japanese coil hve been successfully operated at full current at 8 T. The other coils have operated as background coils while awaiting their turn as test coil. Coil tests have been informative and results gratifying. The facility has capably supported coil testing and its operation has provided information that will be useful in designing future fusion systems. Coil capabilities beyond nominal design points will be determined

  1. Design characteristics for pressurized water small modular nuclear power reactors with focus on safety

    Energy Technology Data Exchange (ETDEWEB)

    Kani, Iraj Mahmoudzadeh [Tehran Univ. (Iran, Islamic Republic of). Civil Faculty; Zandieh, Mehdi [Tehran Univ. (Iran, Islamic Republic of). Civil Faculty; International Univ. of Imam Khomeini (Iran, Islamic Republic of). Architecture Faculty; Abadi, Saeed Kheirollahi Hossein [International Univ. of Imam Khomeini (Iran, Islamic Republic of). Architecture Faculty

    2016-05-15

    Small Modular Reactors (SMRs) are a technology, attracting attention. Light water SMR possess an upgraded design case and emphasize the significance of integral models. Beside of these advantages, SMRs has faced numerous challenges, e.g. licensing, cost/investment, safety and security observation, social and environmental issues in building new plants.

  2. Health economics of blood transfusion safety - focus on sub-Saharan Africa

    NARCIS (Netherlands)

    van Hulst, Marinus; Smit Sibinga, Cees Th. Smit; Postma, Maarten J.

    Background and objectives. Health economics provides a standardised methodology for valid comparisons of interventions in different fields of health care. This review discusses the health economic evaluations of strategies to enhance blood product safety in sub-Saharan Africa Methods. We reviewed

  3. Measuring School Climate in High Schools: A Focus on Safety, Engagement, and the Environment

    Science.gov (United States)

    Bradshaw, Catherine P.; Waasdorp, Tracy E.; Debnam, Katrina J.; Johnson, Sarah Lindstrom

    2014-01-01

    Background: School climate has been linked to multiple student behavioral, academic, health, and social-emotional outcomes. The US Department of Education (USDOE) developed a 3-factor model of school climate comprised of safety, engagement, and environment. This article examines the factor structure and measurement invariance of the USDOE model.…

  4. Open coil traction system.

    Science.gov (United States)

    Vibhute, Pavankumar Janardan

    2012-01-01

    Sliding mechanics have become a popular method for space closure, with the development of preadjusted edgewise appliances. Furthermore, various space closing auxiliaries have been developed and extensively evaluated for their clinical efficiency. Their effectiveness is enhanced with optimum force magnitude and low load deflection rate/force decay. With the advent of nickel-titanium (Ni-Ti) springs in orthodontics, load deflection rates have been markedly reduced. To use Ni-Ti springs, clinicians have to depend upon prefabricated closed coil springs. The open coil traction system, or open coil retraction spring, is developed utilizing Ni-Ti open coil springs for orthodontic space closure. This article describes the fabrication and clinical application of the open coil traction system, which has a number of advantages. It sustains a low load deflection rate with optimum force magnitude, and its design is adjustable for a desired length and force level. It is fail-safe for both activation and deactivation (ie, it cannot be overactivated, and the decompression limit of the open coil is controlled by the operator). The open coil traction system can be offset from the mucosa to help reduce soft tissue impingement.

  5. Coil spring venting arrangement

    International Nuclear Information System (INIS)

    McCugh, R.M.

    1975-01-01

    A simple venting device for trapped gas pockets in hydraulic systems is inserted through a small access passages, operated remotely, and removed completely. The device comprises a small diameter, closely wound coil spring which is pushed through a guide temporarily inserted in the access passage. The guide has a central passageway which directs the coil spring radially upward into the pocket, so that, with the guide properly positioned for depth and properly oriented, the coil spring can be pushed up into the top of the pocket to vent it. By positioning a seal around the free end of the guide, the spring and guide are removed and the passage is sealed

  6. Extending the self-assembly of coiled-coil hybrids

    NARCIS (Netherlands)

    Robson Marsden, Hana

    2009-01-01

    Of the various biomolecular building blocks in use in nature, coiled-coil forming peptides are amongst those with the most potential as building blocks for the synthetic self-assembly of nanostructures. Native coiled coils have the ability to function in, and influence, complex systems composed of

  7. Occupational health and safety challenges in China--focusing on township-village enterprises.

    Science.gov (United States)

    Wang, Xiaorong; Wu, Siying; Song, Qingkun; Tse, Lap-Ah; Yu, Ignatius T S; Wong, Tze-Wai; Griffiths, Sian

    2011-01-01

    China has experienced dramatic industrialization, urbanization, and economic growth over the last 3 decades. The rapid transformation and dramatic prosperity of industries in rural areas have, in turn, created tremendous challenges for occupational health and safety (OHS). This article was prepared to address occupational health and safety issues in township- and village-owned enterprises (TVEs) from several aspects, including working conditions and workplace hazards, major recognized OHS problems, implications of TVE industries to environmental health, and migrant workers. Among the major recognized OHS problems, pneumoconiosis, chemical poisoning, and workplace accidents, especially in small-scale coal mines, are highlighted. It is suggested that the national polices and regulations that specifically target TVEs are indispensable and a more powerful administrative structure should be established to ensure that the pertinent polices, regulations, and OHS standards can be enforced widely and effectively in practice. Copyright © 2011 Taylor & Francis Group, LLC

  8. Relational safety and liberating training spaces: an application with a focus on sexual orientation issues.

    Science.gov (United States)

    Hernández, Pilar; Rankin, Pressley

    2008-04-01

    This article describes and discusses a teaching case of a clinical training situation involving a gay marriage and family therapy student working with a same-sex affectional couple. The conceptual pillars of this teaching case, relational safety and liberating spaces, are advanced as illustrations of how the student developed his voice in the training process. Pivotal moments in this process are discussed, as are implications for training and personal and professional growth.

  9. Health economics of blood transfusion safety--focus on sub-Saharan Africa.

    Science.gov (United States)

    van Hulst, Marinus; Smit Sibinga, Cees Th; Postma, Maarten J

    2010-01-01

    Health economics provides a standardised methodology for valid comparisons of interventions in different fields of health care. This review discusses the health economic evaluations of strategies to enhance blood product safety in sub-Saharan Africa. We reviewed health economic methodology with special reference to cost-effectiveness analysis. We searched the literature for cost-effectiveness in blood product safety in sub-Saharan Africa. HIV-antibody screening in different settings in sub-Saharan Africa showed health gains and saved costs. Except for adding HIV-p24 screening, adding other tests such as nucleic acid amplification testing (NAT) to HIV-antibody screening displayed incremental cost-effectiveness ratios greater than the WHO/World Bank specified threshold for cost-effectiveness. The addition of HIV-p24 in combination with HCV antibody/antigen screening and multiplex (HBV, HCV and HIV) NAT in pools of 24 may also be cost-effective options for Ghana. From a health economic viewpoint, HIV-antibody screening should always be implemented in sub-Saharan Africa. The addition of HIV-p24 antigen screening, in combination with HCV antibody/antigen screening and multiplex (HBV, HCV and HIV) NAT in pools of 24 may be feasible options for Ghana. Suggestions for future health economic evaluations of blood transfusion safety interventions in sub-Saharan Africa are: mis-transfusion, laboratory quality and donor management. Copyright 2009 The International Association for Biologicals. Published by Elsevier Ltd. All rights reserved.

  10. Measuring school climate in high schools: a focus on safety, engagement, and the environment.

    Science.gov (United States)

    Bradshaw, Catherine P; Waasdorp, Tracy E; Debnam, Katrina J; Johnson, Sarah Lindstrom

    2014-09-01

    School climate has been linked to multiple student behavioral, academic, health, and social-emotional outcomes. The US Department of Education (USDOE) developed a 3-factor model of school climate comprised of safety, engagement, and environment. This article examines the factor structure and measurement invariance of the USDOE model. Drawing upon 2 consecutive waves of data from over 25,000 high school students (46% minority), a series of exploratory and confirmatory factor analyses examined the fit of the Maryland Safe and Supportive Schools Climate Survey with the USDOE model. The results indicated adequate model fit with the theorized 3-factor model of school climate, which included 13 subdomains: safety (perceived safety, bullying and aggression, and drug use); engagement (connection to teachers, student connectedness, academic engagement, school connectedness, equity, and parent engagement); environment (rules and consequences, physical comfort, and support, disorder). We also found consistent measurement invariance with regard to student sex, grade level, and ethnicity. School-level interclass correlation coefficients ranged from 0.04 to .10 for the scales. Findings supported the USDOE 3-factor model of school climate and suggest measurement invariance and high internal consistency of the 3 scales and 13 subdomains. These results suggest the 56-item measure may be a potentially efficient, yet comprehensive measure of school climate. © 2014, American School Health Association.

  11. A periodic table of coiled-coil protein structures.

    Science.gov (United States)

    Moutevelis, Efrosini; Woolfson, Derek N

    2009-01-23

    Coiled coils are protein structure domains with two or more alpha-helices packed together via interlacing of side chains known as knob-into-hole packing. We analysed and classified a large set of coiled-coil structures using a combination of automated and manual methods. This led to a systematic classification that we termed a "periodic table of coiled coils," which we have made available at http://coiledcoils.chm.bris.ac.uk/ccplus/search/periodic_table. In this table, coiled-coil assemblies are arranged in columns with increasing numbers of alpha-helices and in rows of increased complexity. The table provides a framework for understanding possibilities in and limits on coiled-coil structures and a basis for future prediction, engineering and design studies.

  12. LHC bending magnet coil

    CERN Multimedia

    A short test version of coil of wire used for the LHC dipole magnets. The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. Magnet coils are made of copper-clad niobium–titanium cables — each wire in the cable consists of 9’000 niobium–titanium filaments ten times finer than a hair.

  13. Borehole induction coil transmitter

    Science.gov (United States)

    Holladay, Gale; Wilt, Michael J.

    2002-01-01

    A borehole induction coil transmitter which is a part of a cross-borehole electromagnetic field system that is used for underground imaging applications. The transmitter consists of four major parts: 1) a wound ferrite or mu-metal core, 2) an array of tuning capacitors, 3) a current driver circuit board, and 4) a flux monitor. The core is wound with several hundred turns of wire and connected in series with the capacitor array, to produce a tuned coil. This tuned coil uses internal circuitry to generate sinusoidal signals that are transmitted through the earth to a receiver coil in another borehole. The transmitter can operate at frequencies from 1-200 kHz and supplies sufficient power to permit the field system to operate in boreholes separated by up to 400 meters.

  14. Bronchoscopic Lung Volume Reduction Coil Treatment of Patients With Severe Heterogeneous Emphysema

    NARCIS (Netherlands)

    Slebos, Dirk-Jan; Klooster, Karin; Ernst, Armin; Herth, Felix J. F.; Kerstjens, Huib A. M.

    Background: The lung volume reduction coil (LVR-coil), a new experimental device to achieve lung volume reduction by bronchoscopy in patients with severe emphysema, works in a manner unaffected by collateral airflow. We investigated the safety and efficacy of LVR-coil treatment in patients with

  15. Structure design of the Westinghouse superconducting magnet for the Large Coil Program

    International Nuclear Information System (INIS)

    Domeisen, F.N.; Hackworth, D.T.; Stuebinger, L.R.

    1978-01-01

    In the on-going development of superconducting toroidal field coils for tokamak reactors, the Large Coil Program (LCP) managed by Union Carbide Corporation will include the design, fabrication, and testing of large superconducting coils to determine their feasibility for use in the magnetic fusion energy effort. Structural analysis of the large coil is essential to ensure adequate safety in the test coil design and confidence in the scalability of the design. This paper will discuss the action of tensile and shear loads on the various materials used in the coil. These loads are of magnetic and thermal origin

  16. Process management - critical safety issues with focus on risk management; Processtyrning - kritiska saekerhetsfraagor med inriktning paa riskhantering

    Energy Technology Data Exchange (ETDEWEB)

    Sanne, Johan M. [Linkoeping Univ. (Sweden). The Tema Inst. - Technology and Social Change

    2005-12-15

    Organizational changes focused on process orientation are taking place among Swedish nuclear power plants, aiming at improving the operation. The Swedish Nuclear Power Inspectorate has identified a need for increased knowledge within the area for its regulatory activities. In order to analyze what process orientation imply for nuclear power plant safety a number of questions must be asked: 1. How is safety in nuclear power production created currently? What significance does the functional organization play? 2. How can organizational forms be analysed? What consequences does quality management have for work and for the enterprise? 3. Why should nuclear power plants be process oriented? Who are the customers and what are their customer values? Which customers are expected to contribute from process orientation? 4. What can one learn from process orientation in other safety critical systems? What is the effect on those features that currently create safety? 5. Could customer values increase for one customer without decreasing for other customers? What is the relationship between economic and safety interests from an increased process orientation? The deregulation of the electricity market have caused an interest in increased economic efficiency, which is the motivation for the interest in process orientation. among other means. It is the nuclear power plants' owners and the distributors (often the same corporations) that have the strongest interest in process orientation. If the functional organization and associated practices are decomposed, the prerequisites of the risk management regime changes, perhaps deteriorating its functionality. When nuclear power operators consider the introduction of process orientation, the Nuclear Power Inspectorate should require that 1. The operators perform a risk analysis beforehand concerning the potential consequences that process orientation might convey: the analysis should contain a model specifying how safety is currently

  17. Superconducting Coil Winding Machine Control System

    Energy Technology Data Exchange (ETDEWEB)

    Nogiec, J. M. [Fermilab; Kotelnikov, S. [Fermilab; Makulski, A. [Fermilab; Walbridge, D. [Fermilab; Trombly-Freytag, K. [Fermilab

    2016-10-05

    The Spirex coil winding machine is used at Fermilab to build coils for superconducting magnets. Recently this ma-chine was equipped with a new control system, which al-lows operation from both a computer and a portable remote control unit. This control system is distributed between three layers, implemented on a PC, real-time target, and FPGA, providing respectively HMI, operational logic and direct controls. The system controls motion of all mechan-ical components and regulates the cable tension. Safety is ensured by a failsafe, redundant system.

  18. Management by process based systems and safety focus; Verksamhetsstyrning med process-baserade ledningssystem och saekerhetsfokus

    Energy Technology Data Exchange (ETDEWEB)

    Rydnert, Bo; Groenlund, Bjoern [SIS Forum AB, Stockholm (Sweden)

    2005-12-15

    An initiative from The Swedish Nuclear Power Inspectorate led to this study carried out in the late autumn of 2005. The objective was to understand in more detail how an increasing use of process management affects organisations, on the one hand regarding risks and security, on the other hand regarding management by objectives and other management and operative effects. The main method was interviewing representatives of companies and independent experts. More than 20 interviews were carried out. In addition a literature study was made. All participating companies are using Management Systems based on processes. However, the methods chosen, and the results achieved, vary extensively. Thus, there are surprisingly few examples of complete and effective management by processes. Yet there is no doubt that management by processes is effective and efficient. Overall goals are reached, business results are achieved in more reliable ways and customers are more satisfied. The weaknesses found can be translated into a few comprehensive recommendations. A clear, structured and acknowledged model should be used and the processes should be described unambiguously. The changed management roles should be described and obeyed extremely legibly. New types of process objectives need to be formulated. In addition one fact needs to be observed and effectively fended off. Changes are often met by mental opposition on management level, as well as among co-workers. This fact needs attention and leadership. Safety development is closely related to the design and operation of a business management system and its continual improvement. A deep understanding of what constitutes an efficient and effective management system affects the understanding of safety. safety culture and abilities to achieve safety goals. Concerning risk, the opinions were unambiguous. Management by processes as such does not result in any further risks. On the contrary. Processes give a clear view of production and

  19. On modular stellarator reactor coils

    International Nuclear Information System (INIS)

    Rau, F.; Harmeyer, E.; Kisslinger, J.; Wobig, H.

    1985-01-01

    Modular twisted coils are discussed which produce magnetic fields of the Advanced Stellarator WENDELSTEIN VII-AS type. Reducing the number coils/FP offers advantage for maintenance of coils, but increases the magnetic ripple and B m /B o . Computation of force densities within the coils of ASR and ASB yield local maximum values of about 80 and 180 MN/m 3 , respectively. A system of mutual coil support is being developed. Twisted coils in helical arrangement provide a reactor-sized HELIAC system. In order to reduce the magnetic ripple, a large number of 14 coils/FP in special arrangement is used

  20. TFTR toroidal field coil design

    International Nuclear Information System (INIS)

    Smith, G.E.; Punchard, W.F.B.

    1977-01-01

    The design of the Tokamak Fusion Test Reactor (TFTR) Toroidal Field (TF) magnetic coils is described. The TF coil is a 44-turn, spiral-wound, two-pancake, water-cooled configuration which, at a coil current of 73.3 kiloamperes, produces a 5.2-Tesla field at a major radius of 2.48 meters. The magnetic coils are installed in titanium cases, which transmit the loads generated in the coils to the adjacent supporting structure. The TFTR utilizes 20 of these coils, positioned radially at 18 0 intervals, to provide the required toroidal field. Because it is very highly loaded and subject to tight volume constraints within the machine, the coil presents unique design problems. The TF coil requirements are summarized, the coil configuration is described, and the problems highlighted which have been encountered thus far in the coil design effort, together with the development tests which have been undertaken to verify the design

  1. NCSX Toroidal Field Coil Design

    International Nuclear Information System (INIS)

    Kalish M; Rushinski J; Myatt L; Brooks A; Dahlgren F; Chrzanowski J; Reiersen W; Freudenberg K.

    2005-01-01

    The National Compact Stellarator Experiment (NCSX) is an experimental device whose design and construction is underway at the Department of Energy's Princeton Plasma Physics Laboratory (PPPL). The primary coil systems for the NCSX device consist of the twisted plasma-shaping Modular Coils, the Poloidal Field Coils, and the Toroidal Field (TF) Coils. The TF Coils are D-shaped coils wound from hollow copper conductor, and vacuum impregnated with a glass-epoxy resin system. There are 18 identical, equally spaced TF coils providing 1/R field at the plasma. They operate within a cryostat, and are cooled by LN2, nominally, to 80K. Wedge shaped castings are assembled to the inboard face of these coils, so that inward radial loads are reacted via the nesting of each of the coils against their adjacent partners. This paper outlines the TF Coil design methodology, reviews the analysis results, and summarizes how the design and analysis support the design requirements

  2. Coil protection calculator for TFTR

    International Nuclear Information System (INIS)

    Marsala, R.J.; Woolley, R.D.

    1987-01-01

    A new coil protection calculator (CPC) is presented in this paper. It is now being developed for TFTR's magnetic field coils will replace the existing coil fault detector. The existing fault detector sacrifices TFTR operating capability for simplicity. The new CPC will permit operation up to the actual coil limits by accurately and continuously computing coil parameters in real-time. The improvement will allow TFTR to operate with higher plasma currents and will permit the optimization of pulse repetition rates

  3. Environment, safety, health, and quality plan for the TRU- Contaminated Arid Soils Project of the Landfill Stabilization Focus Area Program

    International Nuclear Information System (INIS)

    Watson, L.R.

    1995-06-01

    The Landfill Stabilization Focus Area (LSFA) is a program funded by the US Department of Energy Office of Technology Development. LSFA supports the applied research, development, demonstration, testing, and evaluation of a suite of advanced technologies that together form a comprehensive remediation system for the effective and efficient remediation of buried waste. The TRU-Contaminated Arid Soils project is being conducted under the auspices of the LSFA Program. This document describes the Environment, Safety, Health, and Quality requirements for conducting LSFA/Arid Soils activities at the Idaho National Engineering Laboratory. Topics discussed in this report, as they apply to LSFA/Arid Soils operations, include Federal, State of Idaho, and Environmental Protection Agency regulations, Health and Safety Plans, Quality Program, Data Quality Objectives, and training and job hazard analysis. Finally, a discussion is given on CERCLA criteria and system and performance audits as they apply to the LSFA Program

  4. Retrieval of prolapsed coils during endovascular treatment of cerebral aneurysms

    International Nuclear Information System (INIS)

    Dinc, Hasan; Kuzeyli, Kayhan; Kosucu, Polat; Sari, Ahmet; Cekirge, Saruhan

    2006-01-01

    One of the feared complications during detachable coil embolization of cerebral aneurysms is herniation of a coil loop into the parent artery. Although coil protrusion of one or two loops into the parent vessel may not cause adverse events and in some instances can be ignored, the authors believe that coil retrieval is indicated if a free end is seen pulsating along the blood flow stream to prevent migration of the entire coil mass. In one patient, a microballoon was inflated across the neck of the aneurysm during retrieval of a herniated coil to prevent further coil herniation from the aneurysm sac. We present two cases in which prolapsed coils were successfully retrieved either using a microsnare and balloon combination or a microsnare alone. This report focuses on the efficacy of the Amplatz microsnare for such retrievals and the circumstances in which a herniated coil needs to be retrieved. We report two cases in which embolization coils partially migrated into the parent artery during endovascular treatment of cerebral aneurysm and were retrieved using the Amplatz Nitinol microsnare. (orig.)

  5. New method to design stellarator coils without the winding surface

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart R.; Song, Yuntao; Wan, Yuanxi

    2018-01-01

    Finding an easy-to-build coils set has been a critical issue for stellarator design for decades. Conventional approaches assume a toroidal ‘winding’ surface, but a poorly chosen winding surface can unnecessarily constrain the coil optimization algorithm, This article presents a new method to design coils for stellarators. Each discrete coil is represented as an arbitrary, closed, one-dimensional curve embedded in three-dimensional space. A target function to be minimized that includes both physical requirements and engineering constraints is constructed. The derivatives of the target function with respect to the parameters describing the coil geometries and currents are calculated analytically. A numerical code, named flexible optimized coils using space curves (FOCUS), has been developed. Applications to a simple stellarator configuration, W7-X and LHD vacuum fields are presented.

  6. A review of safety-focused mechanical modeling of commercial lithium-ion batteries

    Science.gov (United States)

    Zhu, Juner; Wierzbicki, Tomasz; Li, Wei

    2018-02-01

    We are rapidly approaching an inflection point in the adoption of electric vehicles on the roads. All major automotive companies are having well-funded plans for mass market affordable branded EV product line models, which can open the floodgates. A rapid growth of battery energy density, accompanied by an aggressive progress of reduction of costs of lithium-ion batteries, brings safety concerns. While more energy stored in the battery pack of an EV translates to a longer range, the downside is that accidents will be more violent due to battery inevitable explosion. With today's technology, severe crashes involving intrusion into the battery pack will potentially result in a thermal runaway, fire, and explosion. Most of research on lithium-ion batteries have been concerned with the electrochemistry of cells. However, in most cases failure and thermal runaway is caused by mechanical loading due to crash events. There is a growing need to summarize the already published results on mechanical loading and response of batteries and offer a critical evaluation of work in progress. The objective of this paper is to present such review with a discussion of many outstanding issues and outline of a roadmap for future research.

  7. Topiramate Extended-Release Options: A Focus on Efficacy and Safety in Epilepsy and Comorbidities

    Directory of Open Access Journals (Sweden)

    Yuchen Wang

    2017-02-01

    Full Text Available Topiramate (TPM is effective for multiple seizure types and epilepsy syndromes in children and adults. Topiramate has adverse effects (including cognitive, depression, renal stones, but many of these are low incidence when started at a low dose and slowly titrated to 100 to 200 mg/day. Also, TPM has proven benefit for migraine, obesity, eating disorders, and alcohol use disorders, which can be comorbid in patients with epilepsy and may also be effective in subpopulations within specific psychiatric diagnoses. Recently approved extended-release formulations of TPM (Trokendi and Qudexy in the United States have reliable data supporting their safety and efficacy for patients with epilepsy. They have potential for more rapid titration within 1 month to 200 mg/day and have better patient retention than TPM immediate-release, but there are no robust double-blind randomized controlled trials comparing the different formulations. We expect the once per day extended-release formulations to improve medication adherence compared with the twice per day formulations. This has significant potential to improve outcomes in epilepsy and the other TPM-responsive disorders.

  8. Superconducting coil protection

    International Nuclear Information System (INIS)

    Woods, E.L.

    1975-01-01

    The protection system is based on a two-phase construction program. Phase I is the development of a reliable hardwired relay control system with a digital loop utilizing firmware and a microprocessor controller. Phase II is an expansion of the digital loop to include many heretofore unmonitored coil variables. These new monitored variables will be utilized to establish early quench detection and to formulate confirmation techniques of the quench detection mechanism. Established quench detection methods are discussed and a new approach to quench detection is presented. The new circuit is insensitive to external pulsed magnetic fields and the associated induced voltages. Reliability aspects of the coil protection system are discussed with respect to shutdowns of superconducting coil systems. Redundance and digital system methods are presented as related topics

  9. Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound.

    Science.gov (United States)

    Kobus, Thiele; Vykhodtseva, Natalia; Pilatou, Magdalini; Zhang, Yongzhi; McDannold, Nathan

    2016-02-01

    The purpose of this study was to investigate the effects on the brain of multiple sessions of blood-brain barrier (BBB) disruption using focused ultrasound (FUS) in combination with micro-bubbles over a range of acoustic exposure levels. Six weekly sessions of FUS, using acoustical pressures between 0.66 and 0.80 MPa, were performed under magnetic resonance guidance. The success and degree of BBB disruption was estimated by signal enhancement of post-contrast T1-weighted imaging of the treated area. Histopathological analysis was performed after the last treatment. The consequences of repeated BBB disruption varied from no indications of vascular damage to signs of micro-hemorrhages, macrophage infiltration, micro-scar formations and cystic cavities. The signal enhancement on the contrast-enhanced T1-weighted imaging had limited value for predicting small-vessel damage. T2-weighted imaging corresponded well with the effects on histopathology and could be used to study treatment effects over time. This study demonstrates that repeated BBB disruption by FUS can be performed with no or limited damage to the brain tissue. Copyright © 2016 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  10. Thermal Ablation of the Pancreas With Intraoperative High-Intensity Focused Ultrasound: Safety and Efficacy in a Porcine Model.

    Science.gov (United States)

    Dupré, Aurélien; Melodelima, David; Pflieger, Hannah; Chen, Yao; Vincenot, Jérémy; Kocot, Anthony; Langonnet, Stéphan; Rivoire, Michel

    2017-02-01

    New focal destruction technologies such as high-intensity focused ultrasound (HIFU) may improve the prognosis of pancreatic ductal adenocarcinoma. Our objectives were to demonstrate the safety and efficacy of intraoperative pancreatic HIFU ablation in a porcine model. In a porcine model (N = 12), a single HIFU ablation was performed in either the body or tail of the pancreas, distant to superior mesenteric vessels. All animals were sacrificed on the eighth day. The primary objective was to obtain an HIFU ablation measuring at least 1 cm without premature death. In total, 12 HIFU ablations were carried out. These ablations were performed within 160 seconds and on average measured 20 (15-27) × 16 (8-26) mm. The primary objective was fulfilled in all but 1 pig. There were no premature deaths or severe complications. High-intensity focused ultrasound treatment was associated with a transitory increase in amylase and lipase levels, and pseudocysts were observed in half of the pigs without being clinically apparent. All ablations were well delimited at both gross and histological examinations. Intraoperative thermal destruction of porcine pancreas with HIFU is feasible. Reproducibility and safety have to be confirmed when applied close to mesenteric vessels and in long-term preclinical studies.

  11. [Miscommunication as a risk focus in patient safety : Work process analysis in prehospital emergency care].

    Science.gov (United States)

    Wilk, S; Siegl, L; Siegl, K; Hohenstein, C

    2018-04-01

    In an analysis of a critical incident reporting system (CIRS) in out-of-hospital emergency medicine, it was demonstrated that in 30% of cases deficient communication led to a threat to patients; however, the analysis did not show what exactly the most dangerous work processes are. Current research shows the impact of poor communication on patient safety. An out-of-hospital workflow analysis collects data about key work processes and risk areas. The analysis points out confounding factors for a sufficient communication. Almost 70% of critical incidents are based on human factors. Factors, such as communication and teamwork have an impact but fatigue, noise levels and illness also have a major influence. (I) CIRS database analysis The workflow analysis was based on 247 CIRS cases. This was completed by participant observation and interviews with emergency doctors and paramedics. The 247 CIRS cases displayed 282 communication incidents, which are categorized into 6 subcategories of miscommunication. One CIRS case can be classified into different categories if more communication incidents were validated by the reviewers and four experienced emergency physicians sorted these cases into six subcategories. (II) Workflow analysis The workflow analysis was carried out between 2015 and 2016 in Jena and Berlin, Germany. The focal point of research was to find accumulation of communication risks in different parts of prehospital patient care. During 30 h driving with emergency ambulances, the author interviewed 12 members of the emergency medical service of which 5 were emergency physicians and 7 paramedics. A total of 11 internal medicine cases and one automobile accident were monitored. After patient care the author asked in a 15-min interview if miscommunication or communication incidents occurred. (I) CIRS analysis Between 2005 and 2015, 845 reports were reported to the database. The experts identified 247 incident reports with communication failure. All

  12. NET model coil test possibilities

    International Nuclear Information System (INIS)

    Erb, J.; Gruenhagen, A.; Herz, W.; Jentzsch, K.; Komarek, P.; Lotz, E.; Malang, S.; Maurer, W.; Noether, G.; Ulbricht, A.; Vogt, A.; Zahn, G.; Horvath, I.; Kwasnitza, K.; Marinucci, C.; Pasztor, G.; Sborchia, C.; Weymuth, P.; Peters, A.; Roeterdink, A.

    1987-11-01

    A single full size coil for NET/INTOR represents an investment of the order of 40 MUC (Million Unit Costs). Before such an amount of money or even more for the 16 TF coils is invested as much risks as possible must be eliminated by a comprehensive development programme. In the course of such a programme a coil technology verification test should finally prove the feasibility of NET/INTOR TF coils. This study report is almost exclusively dealing with such a verification test by model coil testing. These coils will be built out of two Nb 3 Sn-conductors based on two concepts already under development and investigation. Two possible coil arrangements are discussed: A cluster facility, where two model coils out of the two Nb 3 TF-conductors are used, and the already tested LCT-coils producing a background field. A solenoid arrangement, where in addition to the two TF model coils another model coil out of a PF-conductor for the central PF-coils of NET/INTOR is used instead of LCT background coils. Technical advantages and disadvantages are worked out in order to compare and judge both facilities. Costs estimates and the time schedules broaden the base for a decision about the realisation of such a facility. (orig.) [de

  13. S-TEAMS: A Truly Multiprofessional Course Focusing on Nontechnical Skills to Improve Patient Safety in the Operating Theater.

    Science.gov (United States)

    Stewart-Parker, Emma; Galloway, Robert; Vig, Stella

    Possessing adequate nontechnical skills (NTS) in operating theaters is of increasing interest to health care professionals, yet these are rarely formally taught. Teams make human errors despite technical expertise and knowledge, compromising patient safety. We designed a 1-day, multiprofessional, multidisciplinary course to teach, practice, and apply these skills through simulation. The course, "S-TEAMS," comprised a morning of lectures, case studies, and interactive teamworking exercises. The afternoon divided the group into multiprofessional teams to rotate around simulated scenarios. During the scenarios, teams were encouraged to focus on NTS, including communication strategies, situational awareness, and prompts such as checklists. A thorough debrief with experienced clinician observers followed. Data was collected through self-assessments, immediate and 6-month feedback to assess whether skills continued to be used and their effect on safety. In total, 68 health care professionals have completed the course thus far. All participants felt the course had a clear structure and that learning objectives were explicit. Overall, 95% felt the scenarios had good or excellent relevance to clinical practice. Self-assessments revealed a 55% increase in confidence for "speaking up" in difficult situations. Long-term data revealed 97% of the participants continued to use the skills, with 88% feeling the course had prevented them from making errors. Moreover, 94% felt the course had directly improved patient safety. There is a real demand and enthusiasm for developing NTS within the modern theater team. The simple and easily reproducible format of S-TEAMS is sustainable and inclusive, and crucially, the skills taught continue to be used in long term to improve patient safety and teamworking. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  14. The importance of Pharmacovigilance for the drug safety: Focus on cardiovascular profile of incretin-based therapy.

    Science.gov (United States)

    Sportiello, Liberata; Rafaniello, Concetta; Scavone, Cristina; Vitale, Cristiana; Rossi, Francesco; Capuano, Annalisa

    2016-01-01

    With the recent introduction of the new European Pharmacovigilance legislation, all new drugs must be carefully monitored after admission on the European market, in order to assess the long safety profile. Currently, special attention is given to several hypoglycemic agents with recent market approval (agonists of glucagon-like peptide-1 [GLP-1] receptor and dipeptidyl peptidase 4 inhibitors [DPP-4i]), which act through the potentiation of incretin hormone signaling. Their inclusion in European additional monitoring is also due to safety problems, which seem to characterize their pharmacological class. In fact, these drugs initially showed a good tolerability profile with mainly gastrointestinal adverse events, low risk of hypoglycemia and minor effects on body weight. But, new concerns such as infections, pancreatitis, pancreatic cancer and above all cardiovascular events (especially risk of heart failure requiring hospitalization) are now arising. In this review, we highlighted aspects of the new Pharmacovigilance European dispositions, and then we investigated the tolerability profile of incretin-based therapies, in particular DPP-4 inhibitors. Notably, we focused our attention on new safety concerns, which are emerging mostly in the post-marketing period, as the cardiovascular risk profile. Evidence in literature and opinions of regulatory agencies (e.g., European Medicines Agency and Food and Drug Administration) about risks of incretin-based therapies are yet controversial, and there are many open questions in particular on cancer and cardiovascular effects. Thus, it is important to continue to monitor closely the use of these drugs in clinical practice to improve the knowledge on their long-term safety and their place in diabetes therapy. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. Lessons Learned During the Manufacture of the NCSX Modular Coils

    International Nuclear Information System (INIS)

    Chrzanowski, James H.; Meighan, Thomas G.; Raftopoulos, Steven; Dudek, Lawrence; Fogarty, Paul J.

    2009-01-01

    The National Compact Stellarator Experiment's (NCSX) modular coils presented a number of engineering and manufacturing challenges due to their complex shapes, requirements for high dimensional accuracy and high current density requirements due to space constraints. Being the first of their kind, these coils required the implementation of many new manufacturing and measuring techniques and procedures. This was the first time that these manufacturing techniques and methods were applied in the production of coils at the laboratory. This resulted in a steep learning curve for the first several coils. Through the effective use of procedures, tooling modifications, involvement and ownership by the manufacturing workforce, and an emphasis on safety, the assembly team was able to reduce the manufacturing times and improve upon the manufacturing methods. This paper will discuss the learning curve and steps that were taken to improve the manufacturing efficiency and reduce the manufacturing times for the modular coils without forfeiting quality

  16. Trim coil power supplies

    International Nuclear Information System (INIS)

    Haisler, R.; Peeler, H.; Zajicek, W.

    1985-01-01

    The 18 trim coil power supplies have been constructed and are now in place in the K500 pit and pit mezzanine. Final wiring of the primary power and control power is proceeding along with installation of cooling water supplies. The supplies are expected to be ready for final testing into resistive loads at the beginning of June, 1985

  17. Eccentric Coil Test Facility (ECTF)

    International Nuclear Information System (INIS)

    Burn, P.B.; Walstrom, P.L.; Anderson, W.C.; Marguerat, E.F.

    1975-01-01

    The conceptual design of a facility for testing superconducting coils under some conditions peculiar to tokamak systems is given. A primary element of the proposed facility is a large 25 MJ background solenoid. Discussions of the mechanical structure, the stress distribution and the thermal stability for this coil are included. The systems for controlling the facility and diagnosing test coil behavior are also described

  18. Modular coils: a promising toroidal-reactor-coil system

    International Nuclear Information System (INIS)

    Chu, T.K.; Furth, H.P.; Johnson, J.L.; Ludescher, C.; Weimer, K.E.

    1981-04-01

    The concept of modular coils originated from a need to find reactor-relevant stellarator windings, but its usefulness can be extended to provide an externally applied, additional rotational transform in tokamaks. Considerations of (1) basic principles of modular coils, (2) types of coils, (3) types of configurations (general, helically symmetric, helically asymmetric, with magnetic well, with magnetic hill), (4) types of rotational transform profile, and (5) structure and origin of ripples are given. These results show that modular coils can offer a wide range of vacuum magnetic field configurations, some of which cannot be obtained with the classical stellarator or torsatron coil configuration

  19. The persuasiveness of online safety cues: The impact of prevention focus compatibility of web content on consumers' risk perceptions, attitudes and intentions

    NARCIS (Netherlands)

    van Noort, G.; Kerkhof, P.; Fennis, B.M.

    2008-01-01

    Safety cues are frequently used in online stores to relieve consumers' risk perceptions concerning online purchases. This paper uses regulatory focus theory (RFT) to predict the persuasiveness of online safety cues. According to RFT (Higgins, 1997), people process information differently depending

  20. The persuasiveness of online safety cues: The impact of prevention focus compatibility of Web content on consumers' risk perceptions, attitudes, and intentions

    NARCIS (Netherlands)

    van Noort, G.; Kerkhof, P.; Fennis, B.M.

    2008-01-01

    Safety cues are frequently used in online stores to relieve consumers' risk perceptions concerning online purchases. This paper uses regulatory focus theory (RFT) to predict the persuasiveness of online safety cues. According to RFT (Higgins, 1997), people process information differently depending

  1. The persuasiveness of online safety cues: The impact of prevention focus compatibility of web content on consumer risk perceptions, attitudes and intentions.

    NARCIS (Netherlands)

    van Noort, Guda; Kerkhof, Peter; Fennis, B.M.

    2008-01-01

    Safety cues are frequently used in online stores to relieve consumers' risk perceptions concerning online purchases. This paper uses regulatory focus theory (RFT) to predict the persuasiveness of online safety cues. According to RFT (Higgins, 1997), people process information differently depending

  2. Optimization of Coil Element Configurations for a Matrix Gradient Coil.

    Science.gov (United States)

    Kroboth, Stefan; Layton, Kelvin J; Jia, Feng; Littin, Sebastian; Yu, Huijun; Hennig, Jurgen; Zaitsev, Maxim

    2018-01-01

    Recently, matrix gradient coils (also termed multi-coils or multi-coil arrays) were introduced for imaging and B 0 shimming with 24, 48, and even 84 coil elements. However, in imaging applications, providing one amplifier per coil element is not always feasible due to high cost and technical complexity. In this simulation study, we show that an 84-channel matrix gradient coil (head insert for brain imaging) is able to create a wide variety of field shapes even if the number of amplifiers is reduced. An optimization algorithm was implemented that obtains groups of coil elements, such that a desired target field can be created by driving each group with an amplifier. This limits the number of amplifiers to the number of coil element groups. Simulated annealing is used due to the NP-hard combinatorial nature of the given problem. A spherical harmonic basis set up to the full third order within a sphere of 20-cm diameter in the center of the coil was investigated as target fields. We show that the median normalized least squares error for all target fields is below approximately 5% for 12 or more amplifiers. At the same time, the dissipated power stays within reasonable limits. With a relatively small set of amplifiers, switches can be used to sequentially generate spherical harmonics up to third order. The costs associated with a matrix gradient coil can be lowered, which increases the practical utility of matrix gradient coils.

  3. Fabrication of built-up conductors for large pulsed coils

    International Nuclear Information System (INIS)

    Henke, M.D.; Schermer, R.I.

    1979-01-01

    The development work was performed to provide a low-loss, cryostable conductor capable of carrying 5 kA at 3 T for a 30-MJ coil cycled at 0.35 Hz. Much of the work is relevant to conductor development for other pulsed coils, such as a tokamak induction heating coil. As part of the development process, various conductor configurations were subjected to ac loss measurements, stability tests, electrical resistance measurements, and mechanical load-bearing and mechanical fatigue tests. The result is a conductor that appears to satisfy the design criteria with a considerable safety margin

  4. Preliminary safety and efficacy results with robotic high-intensity focused ultrasound : A single center Indian experience

    Directory of Open Access Journals (Sweden)

    Shashikant Mishra

    2011-01-01

    Full Text Available Background : There are no Indian data of high-intensity focused ultrasound (HIFU. Being an alternative, still experimental modality, reporting short-term safety outcome is paramount. Aims : This study was aimed at to assess the safety and short-term outcome in patients with prostate cancer treated by HIFU. Settings and Design : A retrospective study of case records of 30 patients undergoing HIFU between January 2008 to September 2010 was designed and conducted. Materials and Methods : The procedural safety was analyzed at 3 months. Follow-up consisted of 3 monthly prostate-specific antigen (PSA levels and transrectal biopsy if indicated. All the patients had a minimum follow-up of 6 months. Results : A mean prostate volume of 26.9 ± 8.5 cm 3 was treated in a mean time of 115 ± 37.4 min. There was no intraoperative complication. The postoperative pain visual analogue score at day 0 was 2.1 ± 1.9 and at day 1 was 0.4 ± 0.8 on a scale of 1-10. Mean duration of perurethral catheter removal was 3.9 days. The complications after treatment were: LUTS in seven patients, stress incontinence in two, stricture in two, and symptomatic urinary tract infection in five. Average follow-up duration was 10.4 months (range, 6-20 months. Mean time to obtain PSA nadir was 6 ± 3 months with a median PSA nadir value of 0.3 ng/ml. Two patients had positive prostatic biopsy in the localized (high risk group. Conclusions : HIFU was safe in carcinoma prostate patients. The short-term results were efficacious in localized disease. The low complication rates and favorable functional outcome support the planning of further larger studies.

  5. Investigating the debate of home birth safety: A critical review of cohort studies focusing on selected infant outcomes.

    Science.gov (United States)

    Elder, Heather R; Alio, Amina P; Fisher, Susan G

    2016-07-01

    There is a debate within the medical community regarding the safety of planned home births. The presumption of increased risk of maternal and infant morbidity and mortality at home due to limited access to life-saving interventions is not clearly supported by research. The aim of the present study was to assess strengths and limitations of the methodological approaches of cohort studies that compare home births with hospital births by focusing on selected infant outcomes. Studies were identified that assess the risk for at least one of three infant outcomes (mortality, Apgar score, and admission to the neonatal intensive care unit [NICU]) of home births compared with hospital births. Fifteen cohort studies were included. Two studies of low-risk births and two including higher risk births found home births to be at an increased risk of neonatal mortality. However, mortality is rare in developed nations and may not be the best measure of safety. When studies focused on low-risk pregnancies, planned birth location, and well-trained birth attendants, there was no difference in neonatal morbidity (Apgar score and NICU admission). Many methodological challenges were identified among these studies. This review contributes to the home birth published work by identifying key strengths and limitations that need to be accounted for in the interpretation of study findings and the development of future studies. Based on this review, the key variables that would strengthen future studies are birth attendant identification, documented planned birth location, and specification of the birth risk level. Uniformity of data collection and minimizing missing data are also critical. © 2016 Japan Academy of Nursing Science.

  6. Use of high current density superconducting coils in fusion devices

    International Nuclear Information System (INIS)

    Green, M.A.

    1979-11-01

    Superconducting magnets will play an important role in fusion research in years to come. The magnets which are currently proposed for fusion research use the concept of cryostability to insure stable operation of the superconducting coils. This paper proposes the use of adiabatically stable high current density superconducting coils in some types of fusion devices. The advantages of this approach are much lower system cold mass, enhanced cryogenic safety, increased access to the plasma and lower cost

  7. Supporting device for Toroidal coils

    International Nuclear Information System (INIS)

    Araki, Takao.

    1985-01-01

    Purpose: To reduce the response of a toroidal coil supporting device upon earthquakes and improve the earthquake proofness in a tokamak type thermonuclear device. Constitution: Structural materials having large longitudinal modulus and enduring great stresses, for example, stainless steels are used as the toroidal coil supporting legs and heat insulating structural materials are embedded in a nuclear reactor base mats below the supporting legs. Furthermore, heat insulating concretes are spiked around the heat insulating structural materials to prevent the intrusion of heat to the toroidal coils. The toroidal coils are kept at cryogenic state and superconductive state for the conductors. In this way, the period of proper vibrations of the toroidal coils and the toroidal coil supporting structures can be shortened thereby decreasing the seismic response. Furthermore, since the strength of the supporting legs is increased, the earthquake proofness of the coils can be improved. (Kamimura, M.)

  8. Structural mapping of the coiled-coil domain of a bacterial condensin and comparative analyses across all domains of life suggest conserved features of SMC proteins.

    Science.gov (United States)

    Waldman, Vincent M; Stanage, Tyler H; Mims, Alexandra; Norden, Ian S; Oakley, Martha G

    2015-06-01

    The structural maintenance of chromosomes (SMC) proteins form the cores of multisubunit complexes that are required for the segregation and global organization of chromosomes in all domains of life. These proteins share a common domain structure in which N- and C- terminal regions pack against one another to form a globular ATPase domain. This "head" domain is connected to a central, globular, "hinge" or dimerization domain by a long, antiparallel coiled coil. To date, most efforts for structural characterization of SMC proteins have focused on the globular domains. Recently, however, we developed a method to map interstrand interactions in the 50-nm coiled-coil domain of MukB, the divergent SMC protein found in γ-proteobacteria. Here, we apply that technique to map the structure of the Bacillus subtilis SMC (BsSMC) coiled-coil domain. We find that, in contrast to the relatively complicated coiled-coil domain of MukB, the BsSMC domain is nearly continuous, with only two detectable coiled-coil interruptions. Near the middle of the domain is a break in coiled-coil structure in which there are three more residues on the C-terminal strand than on the N-terminal strand. Close to the head domain, there is a second break with a significantly longer insertion on the same strand. These results provide an experience base that allows an informed interpretation of the output of coiled-coil prediction algorithms for this family of proteins. A comparison of such predictions suggests that these coiled-coil deviations are highly conserved across SMC types in a wide variety of organisms, including humans. © 2015 Wiley Periodicals, Inc.

  9. Structural design of the superconducting Poloidal Field coils for the Tokamak Physics Experiment

    International Nuclear Information System (INIS)

    O'Connor, T.G.; Zbasnik, J.P.

    1993-01-01

    The Tokamak Physics Experiment concept design uses superconducting coils made from cable-in-conduit conductor to accomplish both magnetic confinement and plasma initiation. The Poloidal Field (PF) magnet system is divided into two subsystems, the central solenoid and the outer ring coils, the latter is focus of this paper. The eddy current heating from the pulsed operation is excessive for a case type construction; therefore, a ''no case'' design has been chosen. This ''no case'' design uses the conductor conduit as the primary structure and the electrical insulation (fiberglass/epoxy wrap) as a structural adhesive. The model integrates electromagnetic analysis and structural analysis into the finite element code ANSYS to solve the problem. PF coil design is assessed by considering a variety of coil current wave forms, corresponding to various operating modes and conditions. The structural analysis shows that the outer ring coils are within the requirements of the fatigue life and fatigue crack growth requirements. The forces produced by the Toroidal Field coils on the PF coils have little effect on the maximum stresses in the PF coils. In addition in an effort to reduce the cost of the coils new elongated PF coils design was proposed which changes the aspect ratio of the outer ring coils to reduce the number of turns in the coils. The compressive stress in the outer ring coils is increased while the tensile stress is decreased

  10. Focused ultrasound-mediated noninvasive blood-brain barrier modulation: preclinical examination of efficacy and safety in various sonication parameters.

    Science.gov (United States)

    Shin, Jaewoo; Kong, Chanho; Cho, Jae Sung; Lee, Jihyeon; Koh, Chin Su; Yoon, Min-Sik; Na, Young Cheol; Chang, Won Seok; Chang, Jin Woo

    2018-02-01

    OBJECTIVE The application of pharmacological therapeutics in neurological disorders is limited by the ability of these agents to penetrate the blood-brain barrier (BBB). Focused ultrasound (FUS) has recently gained attention for its potential application as a method for locally opening the BBB and thereby facilitating drug delivery into the brain parenchyma. However, this method still requires optimization to maximize its safety and efficacy for clinical use. In the present study, the authors examined several sonication parameters of FUS influencing BBB opening in small animals. METHODS Changes in BBB permeability were observed during transcranial sonication using low-intensity FUS in 20 adult male Sprague-Dawley rats. The authors examined the effects of FUS sonication with different sonication parameters, varying acoustic pressure, center frequency, burst duration, microbubble (MB) type, MB dose, pulse repetition frequency (PRF), and total exposure time. The focal region of BBB opening was identified by Evans blue dye. Additionally, H & E staining was used to identify blood vessel damage. RESULTS Acoustic pressure amplitude and burst duration were closely associated with enhancement of BBB opening efficiency, but these parameters were also highly correlated with tissue damage in the sonicated region. In contrast, MB types, MB dose, total exposure time, and PRF had an influence on BBB opening without conspicuous tissue damage after FUS sonication. CONCLUSIONS The study aimed to identify these influential conditions and provide safety and efficacy values for further studies. Future work based on the current results is anticipated to facilitate the implementation of FUS sonication for drug delivery in various CNS disease states in the near future.

  11. Safety

    International Nuclear Information System (INIS)

    1998-01-01

    A brief account of activities carried out by the Nuclear power plants Jaslovske Bohunice in 1997 is presented. These activities are reported under the headings: (1) Nuclear safety; (2) Industrial and health safety; (3) Radiation safety; and Fire protection

  12. Coil Optimization for HTS Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    An optimization approach of HTS coils in HTS synchronous machines (SM) is presented. The optimization is aimed at high power SM suitable for direct driven wind turbines applications. The optimization process was applied to a general radial flux machine with a peak air gap flux density of ~3T...... is suitable for which coil segment is presented. Thus, the performed study gives valuable input for the coil design of HTS machines ensuring optimal usage of HTS tapes....

  13. Large superconducting coil fabrication development

    International Nuclear Information System (INIS)

    Brown, R.L.; Allred, E.L.; Anderson, W.C.; Burn, P.B.; Deaderick, R.I.; Henderson, G.M.; Marguerat, E.F.

    1975-01-01

    Toroidal fields for some fusion devices will be produced by an array of large superconducting coils. Their size, space limitation, and field requirements dictate that they be high performance coils. Once installed, accessibility for maintenance and repairs is severely restricted; therefore, good reliability is an obvious necessity. Sufficient coil fabrication will be undertaken to develop and test methods that are reliable, fast, and economical. Industrial participation will be encouraged from the outset to insure smooth transition from development phases to production phases. Initially, practice equipment for three meter bore circular coils will be developed. Oval shape coil forms will be included in the practice facility later. Equipment that is more automated will be developed with the expectation of winding faster and obtaining good coil quality. Alternate types of coil construction, methods of winding and insulating, will be investigated. Handling and assembly problems will be studied. All technology developed must be feasible for scaling up when much larger coils are needed. Experimental power reactors may need coils having six meter or larger bores

  14. Triple Halo Coil: Development and Comparison with Other TMS Coils

    Science.gov (United States)

    Rastogi, Priyam; Hadimani, Ravi; Jiles, David

    Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation technique that can be used for the treatment of various neurological disorders such as Parkinson's Disease, PTSD, TBI and anxiety by regulating synaptic activity. TMS is FDA approved for the treatment of major depressive disorder. There is a critical need to develop deep TMS coils that can stimulate deeper regions of the brain without excessively stimulating the cortex in order to provide an alternative to surgical methods. We have developed a novel multi-coil configuration called ``Triple Halo Coil'' (THC) that can stimulate deep brain regions. Investigation of induced electric and magnetic field in these regions have been achieved by computer modelling. Comparison of the results due to THC configuration have been conducted with other TMS coils such as ``Halo Coil'', circular coil and ``Figure of Eight'' coil. There was an improvement of more than 15 times in the strength of magnetic field, induced by THC configuration at 10 cm below the vertex of the head when compared with the ``Figure of Eight'' coil alone. Carver Charitable Trust.

  15. The coiled coil motif in polymer drug delivery systems

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert

    2013-01-01

    Roč. 31, č. 1 (2013), s. 90-96 ISSN 0734-9750 R&D Projects: GA ČR GA203/08/0543; GA MŠk 1M0505 Institutional research plan: CEZ:AV0Z40500505 Keywords : coiled coil * hydrophilic polymer * recombinant protein Subject RIV: CD - Macromolecular Chemistry Impact factor: 8.905, year: 2013

  16. Compressing DNA sequence databases with coil

    Directory of Open Access Journals (Sweden)

    Hendy Michael D

    2008-05-01

    Full Text Available Abstract Background Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems. Currently, sequence data is usually kept in large "flat files," which are then compressed using standard Lempel-Ziv (gzip compression – an approach which rarely achieves good compression ratios. While much research has been done on compressing individual DNA sequences, surprisingly little has focused on the compression of entire databases of such sequences. In this study we introduce the sequence database compression software coil. Results We have designed and implemented a portable software package, coil, for compressing and decompressing DNA sequence databases based on the idea of edit-tree coding. coil is geared towards achieving high compression ratios at the expense of execution time and memory usage during compression – the compression time represents a "one-off investment" whose cost is quickly amortised if the resulting compressed file is transmitted many times. Decompression requires little memory and is extremely fast. We demonstrate a 5% improvement in compression ratio over state-of-the-art general-purpose compression tools for a large GenBank database file containing Expressed Sequence Tag (EST data. Finally, coil can efficiently encode incremental additions to a sequence database. Conclusion coil presents a compelling alternative to conventional compression of flat files for the storage and distribution of DNA sequence databases having a narrow distribution of sequence lengths, such as EST data. Increasing compression levels for databases having a wide distribution of sequence lengths is a direction for future work.

  17. Professional autobiography of Professor Leif Svanström - with a focus on injury prevention and safety promotion.

    Science.gov (United States)

    Svanström, Leif

    2012-01-01

    Professor Svanström has spent about forty-five years in the field of Social Medicine and Health and Safety Promotion. His main lines of research and teaching are Injury Epidemiology and Safety Promotion. In the 1960s, he conducted a number of descriptive and analytical studies, and in the 1970s began to address home and occupational injuries. In 1974, he introduced the community approach to safety promotion, encapsulated in the Falköping Model, which has heavily influenced Swedish and international community safety work. Under his leadership of the Research Group on Injury Prevention and Safety Promotion at the Karolinska Institutet in Stockholm, Sweden, more than 30 doctorates have been awarded. His work as Head of the WHO Collaborating Centre on Community Safety Promotion has led to the establishment of Safe Communities worldwide.

  18. Numerical dosimetry of transcranial magnetic stimulation coils

    Science.gov (United States)

    Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique capable of stimulating neurons by means of electromagnetic induction. TMS can be used to map brain function and shows promise for the diagnosis and treatment of neurological and psychiatric disorders. Calculation of fields induced in the brain are necessary to accurately identify stimulated neural tissue during TMS. This allows the development of novel TMS coil designs capable of stimulating deeper brain regions and increasing the localization of stimulation that can be achieved. We have performed numerical calculations of magnetic and electric field with high-resolution anatomically realistic human head models to find these stimulated brain regions for a variety of proposed TMS coil designs. The realistic head models contain heterogeneous tissue structures and electrical conductivities, yielding superior results to those obtained from the simplified homogeneous head models that are commonly employed. The attenuation of electric field as a function of depth in the brain and the localization of stimulating field have been methodically investigated. In addition to providing a quantitative comparison of different TMS coil designs the variation of induced field between subjects has been investigated. We also show the differences in induced fields between adult, adolescent and child head models to preemptively identify potential safety issues in the application of pediatric TMS.

  19. Superconducting cyclotron magnet coil short

    International Nuclear Information System (INIS)

    Mallory, M.L.; Blosser, H.G.; Clark, D.J.; Launer, H.; Lawton, D.; Miller, P.; Resmini, F.

    1982-01-01

    In February 1981, a short circuit appeared in the superconducting coil of the K500 cyclotron. The short is resistive in character and therefore has no effect on steady state operation of the magnet. The resistance of the short varies, sometimes being below threshold of detection as a heat load on the cooling system and sometimes being significant. The resistance under certain conditions shows approximately cyclic phenomena with time constants in the range of seconds and other approximately cyclic phenomena which correlate with gross operating parameters of the magnet (shifting current from one coil to another at high field and lowering and raising the liquid helium level). A number of diagnostic studies of the short have been made, using 1) an array of flux sensing loops to sense the magnetic effect of the short, 2) voltage comparisons between upper and lower sections of the coil, 3) comparisons of forces in the nine member coil support system and 4) the effect of the short on the thermal charactersitics of the coil. Insulation failure or a metal chip shorting out turns have been explored in some detail but a convincing determination of the exact cause of the short may never be available, (even the extreme step of unwinding the coil having a significant probability that an imperfection with the observed characteristics would pass unnoticed). Analysis of the characteristics of the short indicated that the most serious consequence would be failure of the coils mechanical support system in the event that the magnet was quickly discharged, as in a dump or quench. To deal with this hazard, the support system has been modified by installing solid supports which prevent the coil from moving by an amount sufficient to damage the support system. We have also reexamined the data and calculations used in the original coil design and have made some additional measurements of the properties of the materials (yield strength, friction coefficient, Young's modulus) used in the

  20. Lung volume reduction coil treatment for patients with severe emphysema : a European multicentre trial

    NARCIS (Netherlands)

    Deslee, Gaetan; Klooster, Karin; Hetzel, Martin; Stanzel, Franz; Kessler, Romain; Marquette, Charles-Hugo; Witt, Christian; Blaas, Stefan; Gesierich, Wolfgang; Herth, Felix J. F.; Hetzel, Juergen; van Rikxoort, Eva M.; Slebos, Dirk-Jan

    2014-01-01

    Background The lung volume reduction (LVR) coil is a minimally invasive bronchoscopic nitinol device designed to reduce hyperinflation and improve elastic recoil in severe emphysema. We investigated the feasibility, safety and efficacy of LVR coil treatment in a prospective multicentre cohort trial

  1. Superconducting poloidal coils for STARFIRE commercial reactor

    International Nuclear Information System (INIS)

    Wang, S.T.; Evans, K. Jr.; Turner, L.R.; Huang, Y.C.; Prater, R.; Alcorn, J.

    1979-01-01

    STARFIRE is considered to be the tenth commercial tokamak power plant. A preliminary design study on its superconducting poloidal coil system is presented. Key features of the design studies are: the elimination of the ohmic heating coil; the trade-off studies of the equilibrium field coil locations; and the development of a conceptual design for the superconducting equilibrium field coils. Described are the 100 kA cryostable conductor design, the coil structure, and evaluation of the coil forces

  2. 48{sup th} Annual meeting on nuclear technology (AMNT 2017). Key topic / Enhanced safety and operation excellence. Focus session: International operational experience

    Energy Technology Data Exchange (ETDEWEB)

    Mohrbach, Ludger [VGB PowerTech e.V., Essen (Germany). Abteilung ' ' N' ' ; Gottschling, Helge

    2017-11-15

    Summary report on the Key Topic Enhanced Safety and Operation Excellence: Focus Session: International Operational Experience and the Nuclear Energy Campus of the 48{sup th} Annual Meeting on Nuclear Technology (AMNT 2017) held in Berlin, 16 to 17 May 2017.

  3. Design features of the KSTAR in-vessel control coils

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.K. [National Fusion Research Institute (NFRI), 52 Yeoeun-dong, Yusung-ku, Daejeon, 305-333 (Korea, Republic of)], E-mail: hkkim@nfri.re.kr; Yang, H.L.; Kim, G.H.; Kim, Jin-Yong; Jhang, Hogun; Bak, J.S.; Lee, G.S. [National Fusion Research Institute (NFRI), 52 Yeoeun-dong, Yusung-ku, Daejeon, 305-333 (Korea, Republic of)

    2009-06-15

    In-vessel control coils (IVCCs) are to be used for the fast plasma position control, field error correction (FEC), and resistive wall mode (RWM) stabilization for the Korea Superconducting Tokamak Advanced Research (KSTAR) device. The IVCC system comprises 16 segments to be unified into a single set to achieve following remarkable engineering advantages; (1) enhancement of the coil system reliability with no welding or brazing works inside the vacuum vessel, (2) simplification in fabrication and installation owing to coils being fabricated outside the vacuum vessel and installed after device assembly, and (3) easy repair and maintenance of the coil system. Each segment is designed in 8 turns coil of 32 mm x 15 mm rectangular oxygen free high conductive copper with a 7 mm diameter internal coolant hole. The conductors are enclosed in 2 mm thick Inconel 625 rectangular welded vacuum jacket with epoxy/glass insulation. Structural analyses were implemented to evaluate structural safety against electromagnetic loads acting on the IVCC for the various operation scenarios using finite element analysis. This paper describes the design features and structural analysis results of the KSTAR in-vessel control coils.

  4. Traffic safety issues in North Dakota : phase II : driver knowledge, attitude, behavior and beliefs : focus group : young male drivers

    Science.gov (United States)

    2008-10-01

    Traffic safety is a widespread social concern. Tackling the problem requires understanding the people : who are driving. This includes information about driver behavior, but also about perceptions these drivers : hold regarding their driving. North D...

  5. Coil protection calculator for TFTR

    International Nuclear Information System (INIS)

    Marsala, R.J.; Lawson, J.E.; Persing, R.G.; Senko, T.R.; Woolley, R.D.

    1989-01-01

    A new coil protection system (CPS) is being developed to replace the existing TFTR magnetic coil fault detector. The existing fault detector sacrifices TFTR operating capability for simplicity. The new CPS, when installed in October of 1988, will permit operation up to the actual coil stress limits parameters in real-time. The computation will be done in a microprocessor based Coil Protection Calculator (CPC) currently under construction at PPL. THe new CPC will allow TFTR to operate with higher plasma currents and will permit the optimization of pulse repetition rates. The CPC will provide real-time estimates of critical coil and bus temperatures and stresses based on real-time redundant measurements of coil currents, coil cooling water inlet temperature, and plasma current. The critical parameter calculations are compared to prespecified limits. If these limits are reached or exceeded, protection action will be initiated to a hard wired control system (HCS), which will shut down the power supplies. The CPC consists of a redundant VME based microprocessor system which will sample all input data and compute all stress quantities every ten milliseconds. Thermal calculations will be approximated every 10ms with an exact solution occurring every second. The CPC features continuous cross-checking of redundant input signal, automatic detection of internal failure modes, monitoring and recording of calculated results, and a quick, functional verification of performance via an internal test system. (author)

  6. Public Communication Strategy Development: Focused on the Public Opinion Poll and Lessons Learned from the Survey on Nuclear Safety

    International Nuclear Information System (INIS)

    Hah, Yeon Hee; Chung, Yun Hyung; Lee, Gey Hwi; Choi, Yong Seog

    2006-01-01

    The fundamental objective of nuclear regulatory organization is to ensure that nuclear activities are conducted at all times in an acceptably safe manner. When we are talking about 'acceptable' safety, it means that we have to try to achieve the safety level as 'acceptable' as perceived by the public, not the one conceptualized by the technology itself. In meeting this objective, the regulatory organization continues to ensure that its activities are transparent, technically sound, credible, and independent. More importantly, it should strive to ensure that the public are well informed about such activities and are confident upon regulatory organization. Public communication is one of the key approaches to attain such a goal. The availability of on-line communications based on the development of information technology has made a major impact on the public's better awareness of nuclear safety issues. Nuclear regulatory organization and operators are increasingly under pressure to communicate more actively with the public to satisfy their demand for knowing about the safety of nuclear facility. In coping with such challenges, KINS has developed a public information and communication policy to make public confident in their information and thus to earn the public trust and confidence toward nuclear safety. It is widely acknowledged that public communication for ensuring nuclear safety has been an integral part of the operators' activity. However, the roles and activities by the regulator in the area of public communication are increasingly required as the public become more interested in and concerned about safety issues. Taking this into account, KINS has carried out several activities to be well-informed about how the public perceive nuclear safety and how much they are satisfied with the regulator's activities, etc

  7. SAFETY

    CERN Multimedia

    Niels Dupont

    2013-01-01

    CERN Safety rules and Radiation Protection at CMS The CERN Safety rules are defined by the Occupational Health & Safety and Environmental Protection Unit (HSE Unit), CERN’s institutional authority and central Safety organ attached to the Director General. In particular the Radiation Protection group (DGS-RP1) ensures that personnel on the CERN sites and the public are protected from potentially harmful effects of ionising radiation linked to CERN activities. The RP Group fulfils its mandate in collaboration with the CERN departments owning or operating sources of ionising radiation and having the responsibility for Radiation Safety of these sources. The specific responsibilities concerning "Radiation Safety" and "Radiation Protection" are delegated as follows: Radiation Safety is the responsibility of every CERN Department owning radiation sources or using radiation sources put at its disposition. These Departments are in charge of implementing the requi...

  8. Depletion-Mode GaN HEMT Q-Spoil Switches for MRI Coils.

    Science.gov (United States)

    Lu, Jonathan Y; Grafendorfer, Thomas; Zhang, Tao; Vasanawala, Shreyas; Robb, Fraser; Pauly, John M; Scott, Greig C

    2016-12-01

    Q-spoiling is the process of decoupling an MRI receive coil to protect the equipment and patient. Conventionally, Q-spoiling is performed using a PIN diode switch that draws significant current. In this work, a Q-spoiling technique using a depletion-mode Gallium Nitride HEMT device was developed for coil detuning at both 1.5 T and 3 T MRI. The circuits with conventional PIN diode Q-spoiling and the GaN HEMT device were implemented on surface coils. SNR was measured and compared for all surfaces coils. At both 1.5 T and 3 T, comparable SNR was achieved for all coils with the proposed technique and conventional Q-spoiling. The GaN HEMT device has significantly reduced the required power for Q-spoiling. The GaN HEMT device also provides useful safety features by detuning the coil when unpowered.

  9. Occupational health and safety for agricultural workers in Thailand: gaps and recommendations, with a focus on pesticide use.

    Science.gov (United States)

    Kaewboonchoo, Orawan; Kongtip, Pornpimol; Woskie, Susan

    2015-05-01

    Over 16.7 million workers in Thailand (42 percent of the working population) are engaged in agriculture, disproportionately from the lower socioeconomic strata of Thai society. Most agricultural workers (over 93 percent) work in the informal sector without the protections of regulations or enforcement of labor or health and safety laws or enrollment in a social security system. Although Thailand's use of herbicides, fungicides, and insecticides is growing, there is little regulation of the sale, use, or application of these potentially toxic chemicals. This paper summarizes the research to date on occupational health and safety for Thai agricultural workers, identifies gaps in pesticide regulations and the current systems for occupational health and safety and social support for Thai agricultural workers, and makes recommendations for future policy and research initiatives to fill the identified gaps. © The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  10. Coil for LEAR extraction septum

    CERN Multimedia

    CERN PhotoLab

    1982-01-01

    Which way does the current flow ? This intriguing object is the coil for the LEAR extraction septum. There were two septa, first a thin one, then this one, not so thin, somewhat on the borderline between septum and bending magnet.

  11. First coil for the SC

    CERN Multimedia

    CERN PhotoLab

    1955-01-01

    The coils for the SC magnet were stored in the large hangar of the Cointrin Airport (to make sure that they would be available before snow and ice would block the roads and canals from Belgium, where they were built).

  12. Safety

    International Nuclear Information System (INIS)

    2001-01-01

    This annual report of the Senior Inspector for the Nuclear Safety, analyses the nuclear safety at EDF for the year 1999 and proposes twelve subjects of consideration to progress. Five technical documents are also provided and discussed concerning the nuclear power plants maintenance and safety (thermal fatigue, vibration fatigue, assisted control and instrumentation of the N4 bearing, 1300 MW reactors containment and time of life of power plants). (A.L.B.)

  13. Radiation resistant ducted superconductive coil

    International Nuclear Information System (INIS)

    Schleich, A.

    1976-01-01

    The radiation-resistant ducted superconductive coil consists of a helically wound electrical conductor constituted by an electrically conductive core of superconductive material provided with a longitudinally extending cooling duct. The core is covered with a layer of inorganic insulating material and the duct is covered by an electrically conductive metallic gas-tight sheath. The metallic sheaths on adjacent turns of the coil are secured together. 2 Claims, 4 Drawing Figures

  14. The Swiss LCT-coil

    International Nuclear Information System (INIS)

    Vecsey, G.; Benz, H.; Horvath, I.

    1985-01-01

    With delivery of the coil to ORNL on February 4, 1984, the second phase of the Swiss Large Coil Program - design and construction - was terminated. Mainlines of the Swiss design concept are summarized and related to theoretical calculations, experimental results of the supporting program, fabricational experience and first successful test results. An attempt is made to draw preliminary conclusions with regard to the design of future toroidal systems such as NET

  15. The SMES model coil. Fabrication

    International Nuclear Information System (INIS)

    Hanai, Satoshi; Nakamoto, Kazunari; Takahashi, Nobuji

    1998-01-01

    A SMES model coil was fabricated as R and D item in the development of component technologies for a 480 MJ/20 MW SMES pilot plant. The coil consists of four double-pancake windings. The coil is the same diameter but half the number of pancakes that will be needed for a SMES pilot plant. The NbTi cable-in-conduit conductor and superconducting joints between the double pancakes are cooled by a forced flow of supercritical helium. Prior to fabrication, various characteristics of the cable-in-conduit were measured by full-sized short samples from actual conductors and by scaled short samples from scaled conductors. The critical current of the scaled short samples was in agreement with that calculated from one strand of the conductor. The impedance between arbitrary dual-oxide coated strands in the full-size conductor was measured to be smaller than that obtained from two Cr-plated strands, which showed a good degree of stability in another coil. It was estimated that oxide-coated conductors would have high stability. Through fabrication of a model coil, it was demonstrated that a large forced-flow coil for a small-scale 100 kWh SMES device could be manufactured. (author)

  16. The SMES model coil. Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Hanai, Satoshi; Nakamoto, Kazunari; Takahashi, Nobuji [Toshiba Corp., Yokohama, Kanagawa (Japan)] [and others

    1998-07-01

    A SMES model coil was fabricated as R and D item in the development of component technologies for a 480 MJ/20 MW SMES pilot plant. The coil consists of four double-pancake windings. The coil is the same diameter but half the number of pancakes that will be needed for a SMES pilot plant. The NbTi cable-in-conduit conductor and superconducting joints between the double pancakes are cooled by a forced flow of supercritical helium. Prior to fabrication, various characteristics of the cable-in-conduit were measured by full-sized short samples from actual conductors and by scaled short samples from scaled conductors. The critical current of the scaled short samples was in agreement with that calculated from one strand of the conductor. The impedance between arbitrary dual-oxide coated strands in the full-size conductor was measured to be smaller than that obtained from two Cr-plated strands, which showed a good degree of stability in another coil. It was estimated that oxide-coated conductors would have high stability. Through fabrication of a model coil, it was demonstrated that a large forced-flow coil for a small-scale 100 kWh SMES device could be manufactured. (author)

  17. Equilibrium field coil concepts for INTOR

    International Nuclear Information System (INIS)

    Strickler, D.J.; Peng, Y.K.M.; Brown, T.G.

    1981-08-01

    Methods are presented for reducing ampere-turn requirements in the EF coil system. It is shown that coil currents in an EF coil system external to the toroidal field coils can be substantially reduced by relaxing the triangularity of a D-shaped plasma. Further reductions are realized through a hybrid EF coil system using both internal and external coils. Equilibrium field coils for a poloidally asymmetric, single-null INTOR configuration are presented. It is shown that the shape of field lines in the plasma scrapeoff region and divertor channel improves as triangularity is reduced, but it does so at the possible expense of achievable stable beta values

  18. Endovascular rescue method for undesirably stretched coil.

    Science.gov (United States)

    Cho, Jae Hoon

    2014-10-01

    Undesirable detachment or stretching of coils within the parent artery during aneurysm embolization can be related with thrombus formation, which can be caused occlusion of parent artery or embolic event(s). To escape from this situation, several rescue methods have been reported. A case with undesirably stretched coil in which another rescue method was used, is presented. When the stretched coil is still located in the coil delivery microcatheter, the stretched coil can be removed safely using a snare and a handmade monorail microcatheter. After a snare is lodged in the handmade monorail microcatheter, the snare is introduced over the coil delivery micorcatheter and located in the distal part of the stretched coil. After then, the handmade monorail microcatheter captures the stretched coil and the snare as one unit. This technique using a handmade monorail microcatheter and a snare can be a good rescue modality for the undesirably stretched coil, still remained within the coil delivery microcatheter.

  19. Development and testing of the cooling coil cleaning end effector

    International Nuclear Information System (INIS)

    Johnson, K.I.; Mullen, O.D.; Powell, M.R.; Daly, D.S.; Engel, D.W.

    1997-01-01

    The Retrieval Process Development and Enhancement (KPD ampersand E) program has developed and tested an end effector to support the waste retrieval mission at the Idaho National Engineering and Environmental Laboratory (INEEL). The end effector was developed specifically to remove a sticky waste material from the cooling coils in the High Level Liquid Waste (HLLW) tank, and to vacuum up a sediment layer that has settled beneath the cooling coils. An extensive testing program was conducted in the hydraulic test bed (HTB) at the Pacific Northwest National Laboratory (PNNL) to evaluate the performance of the end effector under simulated in-tank conditions. A mock up of the cooling coils was installed in the test bed tank, and simulated waste materials were included to represent the sticky waste on the tubes and the particulate waste settled beneath them. The testing program focused on assessing long-duration mining strategies for cleaning the cooling coils and removing the particulate waste forms. The report describes the results of the end effector testing program at PNNL. Section 2 describes the physical characteristics of the HLLW tanks, including the layout of the cooling coils, and it also describes what is known of the waste forms in the tanks. Section 3 describes the cleaning and retrieval strategy that was used in developing the end effector design. Section 4 describes the cooling coil mockup in the hydraulic test bed. Section 5 discusses the rationale used in selecting the simulants for the tarry waste and particulate waste forms. Section 6 describes the tests that were performed to evaluate cleaning of the cooling coils and retrieval of the particulate simulant. Section 7 summarizes the cleaning and retrieval tests, assesses the relative importance of cleaning the cooling coils and retrieving the particulate waste, and suggests modifications that would simplify the end effector design

  20. Coil supporting device in nuclear fusion apparatus

    International Nuclear Information System (INIS)

    Hoshi, Ryo; Imura, Yasuya.

    1974-01-01

    Object: To secure intermediate fittings with a coil fixed thereon by an insulating tape to a fixed body by means of fittings, thereby supporting the coil in a narrow space. Structure: A coil is secured to intermediate fittings by means of an insulating tape, after which the intermediate fittings is mounted on a fixed body through fittings to support the coil in a narrow clearance portion between a plasma sealed vessel and a main coil. (Kamimura, M.)

  1. Occupational Health and Safety for Agricultural Workers in Thailand: Gaps and Recommendations, with a Focus on Pesticide Use

    OpenAIRE

    Kaewboonchoo, Orawan; Kongtip, Pornpimol; Woskie, Susan

    2015-01-01

    Over 16.7 million workers in Thailand (42 percent of the working population) are engaged in agriculture, disproportionately from the lower socioeconomic strata of Thai society. Most agricultural workers (over 93 percent) work in the informal sector without the protections of regulations or enforcement of labor or health and safety laws or enrollment in a social security system. Although Thailand’s use of herbicides, fungicides, and insecticides is growing, there is little regulation of the sa...

  2. Design of the dummy coil for magnet power supply

    International Nuclear Information System (INIS)

    Kim, Chang-Hwan; Choi, Jae-Hoon; Jin, Jong-Kook; Lee, Dong-Keun; Kong, Jong-Dea; Joung, Nam-Young; Kim, Sang-Tae; Kim, Young-Jin; Kim, Yang-Soo; Kwon, Myeun

    2013-01-01

    Highlights: • It is necessary to confirm safety of the MPS on a dummy coil before the operating it. • We selected and designed the water cooling type dummy coil to test on the MPS's rating (12.5 kA) test. • For the design of the dummy coil, we considered requirements about electrical, structural and water cooling. • We will test as the rating power after MPS upgrade and that test will do before every KSTAR campaign. -- Abstract: It is necessary to test it on a dummy coil, before using a magnet power supply (MPS) to energize a Poloidal Field (PF) coil in the Korea Superconducting Tokamak Advanced Research (KSTAR) device. The dummy coil should accept the same large current from the MPS as the PF coil and be within the capability of the utilities located at the KSTAR site. Therefore a coil design based on the characteristics of the MPS and other restrictive conditions needed to be made. There are three requirements to be met in the design: an electrical requirement, a structural requirement, and a water cooling requirement. The electrical requirement was that the coil should have an inductance of 40 mH. For the structural requirement, the material should be non magnetic. The coil support structure and water cooling manifold were made of SUS 304. The water cooling requirement was that there should be sufficient flow rate so that the temperature rise ΔT should not exceed 12 °C for operation at 12.5 kA for 5 min. Square cross-section hollow conductor with dimensions of 38.1 mm × 38.1 mm was used with a 25.4 mm center hole for cooling water. However, as a result of tests, it was found that the electrical and structural requirements were satisfied but that the water cooling was over designed. It is imperative that the verification will be redone for a test with 12.5 kA for 5 min

  3. Design of the dummy coil for magnet power supply

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang-Hwan, E-mail: kch2004@nfri.re.kr; Choi, Jae-Hoon; Jin, Jong-Kook; Lee, Dong-Keun; Kong, Jong-Dea; Joung, Nam-Young; Kim, Sang-Tae; Kim, Young-Jin; Kim, Yang-Soo; Kwon, Myeun

    2013-11-15

    Highlights: • It is necessary to confirm safety of the MPS on a dummy coil before the operating it. • We selected and designed the water cooling type dummy coil to test on the MPS's rating (12.5 kA) test. • For the design of the dummy coil, we considered requirements about electrical, structural and water cooling. • We will test as the rating power after MPS upgrade and that test will do before every KSTAR campaign. -- Abstract: It is necessary to test it on a dummy coil, before using a magnet power supply (MPS) to energize a Poloidal Field (PF) coil in the Korea Superconducting Tokamak Advanced Research (KSTAR) device. The dummy coil should accept the same large current from the MPS as the PF coil and be within the capability of the utilities located at the KSTAR site. Therefore a coil design based on the characteristics of the MPS and other restrictive conditions needed to be made. There are three requirements to be met in the design: an electrical requirement, a structural requirement, and a water cooling requirement. The electrical requirement was that the coil should have an inductance of 40 mH. For the structural requirement, the material should be non magnetic. The coil support structure and water cooling manifold were made of SUS 304. The water cooling requirement was that there should be sufficient flow rate so that the temperature rise ΔT should not exceed 12 °C for operation at 12.5 kA for 5 min. Square cross-section hollow conductor with dimensions of 38.1 mm × 38.1 mm was used with a 25.4 mm center hole for cooling water. However, as a result of tests, it was found that the electrical and structural requirements were satisfied but that the water cooling was over designed. It is imperative that the verification will be redone for a test with 12.5 kA for 5 min.

  4. Core/coil assembly for use in superconducting magnets and method for assembling the same

    Science.gov (United States)

    Kassner, David A.

    1979-01-01

    A core/coil assembly for use in a superconducting magnet of the focusing or bending type used in syncronous particle accelerators comprising a coil assembly contained within an axial bore of the stacked, washer type, carbon steel laminations which comprise the magnet core assembly, and forming an interference fit with said laminations at the operating temperature of said magnet. Also a method for making such core/coil assemblies comprising the steps of cooling the coil assembly to cryogenic temperatures and drawing it rapidly upwards into the bore of said stacked laminations.

  5. Remote replacement of TF [toroidal field] and PF [poloidal field] coils for the compact ignition tokamak

    International Nuclear Information System (INIS)

    Macdonald, D.; Watkin, D.C.; Hollis, M.J.; DePew, R.E.; Kuban, D.P.

    1990-01-01

    The use of deuterium-tritium fuel in the Compact Ignition Tokamak will require applying remote handling technology for ex-vessel maintenance and replacement of machine components. Highly activated and contaminated components of the fusion devices auxiliary systems, such as diagnostics and RF heating, must be replaced using remotely operated maintenance equipment in the test cell. In-vessel remote maintenance included replacement of divertor and first wall hardware, faraday shields, and for an in-vessel inspection system. Provision for remote replacement of a vacuum vessel sector, toroidal field coil or poloidal field ring coil was not included in the project baseline. As a result of recent coil failures experienced at a number of facilities, the CIT project decided to reconsider the question of remote recovery from a coil failure and, in January of 1990, initiated a coil replacement study. This study focused on the technical requirements and impact on fusion machine design associated with remote recovery from any coil failure

  6. Hessian matrix approach for determining error field sensitivity to coil deviations

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart R.; Lazerson, Samuel A.; Song, Yuntao; Wan, Yuanxi

    2018-05-01

    The presence of error fields has been shown to degrade plasma confinement and drive instabilities. Error fields can arise from many sources, but are predominantly attributed to deviations in the coil geometry. In this paper, we introduce a Hessian matrix approach for determining error field sensitivity to coil deviations. A primary cost function used for designing stellarator coils, the surface integral of normalized normal field errors, was adopted to evaluate the deviation of the generated magnetic field from the desired magnetic field. The FOCUS code (Zhu et al 2018 Nucl. Fusion 58 016008) is utilized to provide fast and accurate calculations of the Hessian. The sensitivities of error fields to coil displacements are then determined by the eigenvalues of the Hessian matrix. A proof-of-principle example is given on a CNT-like configuration. We anticipate that this new method could provide information to avoid dominant coil misalignments and simplify coil designs for stellarators.

  7. Results of the international Large Coil Task: a milestone for superconducting magnets in fusion power

    International Nuclear Information System (INIS)

    Dresner, L.; Fietz, W.A.; Gauss, S.

    1989-01-01

    The aim of the Large Coil Task (LCT) was to demonstrate the reliable operation of large superconducting toroidal field coils and to prove the design principles and fabrication techniques to be applied for the magnets in a tokamak experimental power reactor. This has been achieved by an international development effort involving the US DOE, EURATOM, JAERI and the Swiss government. Six different D-shaped test coils were separately designed, developed and constructed by the LCT participants, then extensively tested together in a compact toroidal array. Detailed information on coil design and manufacture and all test data were shared among the LCT participants. The full six-coil array tests were carried out in a continuous period from the beginning of 1986 until September 1987. Beside the originally planned tests to reach an 8 T design point performance, the tests went well beyond this goal, reaching 9 T peak field in each coil. The experiments also delineated the limits of operability and demonstrated the coil safety under abnormal conditions. For fusion application the transient a.c. field behaviour in the coils was also of great interest. Three of the coils have been tested in this respect and showed excellent performance, with loss values in agreement with the theoretical predictions. (author)

  8. CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

    DEFF Research Database (Denmark)

    Bartoli, Lisa; Fariselli, Piero; Krogh, Anders

    2009-01-01

    tools are available for predicting coiled-coil domains in protein sequences, including those based on position-specific score matrices and machine learning methods. RESULTS: In this article, we introduce a hidden Markov model (CCHMM_PROF) that exploits the information contained in multiple sequence...... alignments (profiles) to predict coiled-coil regions. The new method discriminates coiled-coil sequences with an accuracy of 97% and achieves a true positive rate of 79% with only 1% of false positives. Furthermore, when predicting the location of coiled-coil segments in protein sequences, the method reaches...

  9. Transient voltage oscillations in coils

    International Nuclear Information System (INIS)

    Chowdhuri, P.

    1985-01-01

    Magnet coils may be excited into internal voltage oscillations by transient voltages. Such oscillations may electrically stress the magnet's dielectric components to many times its normal stress. This may precipitate a dielectric failure, and the attendant prolonged loss of service and costly repair work. Therefore, it is important to know the natural frequencies of oscillations of a magnet during the design stage, and to determine whether the expected switching transient voltages can excite the magnet into high-voltage internal oscillations. The series capacitance of a winding significantly affects its natural frequencies. However, the series capacitance is difficult to calculate, because it may comprise complex capacitance network, consisting of intra- and inter-coil turn-to-turn capacitances of the coil sections. A method of calculating the series capacitance of a winding is proposed. This method is rigorous but simple to execute. The time-varying transient voltages along the winding are also calculated

  10. Large coil program support structure conceptual design

    International Nuclear Information System (INIS)

    Litherland, P.S.

    1977-01-01

    The purpose of the Large Coil Program (LCP) is to perform tests on both pool boiling and force cooled superconducting toroidal field coils. The tests will attempt to approximate conditions anticipated in an ignition tokamak. The test requirements resulted in a coil support design which accommodates up to six (6) test coils and is mounted to a structure capable of resisting coil interactions. The steps leading to the present LCP coil support structure design, details on selected structural components, and the basic assembly sequence are discussed

  11. Cooling device of superconducting coils

    International Nuclear Information System (INIS)

    Duthil, R.; Lottin, J.C.

    1985-01-01

    This device is rotating around an horizontal axis. The superconducting coils are contained in a cryogenic enclosure feeded in liquid helium forced circulation. They are related to an electric generator by electric mains each of them comprising a gas exchanger, and an exchanger-evaporator set between the cryogenic device and those exchangers. The exchanger-evaporator is aimed at dissipating the heat arriving by conductors connected to the superconducting coils. According to the invention, the invention includes an annular canalization with horizontal axis in which the connection conductors bathe in liquid helium [fr

  12. Large Coil Program magnetic system design study

    International Nuclear Information System (INIS)

    Moses, S.D.; Johnson, N.E.

    1977-01-01

    The primary objective of the Large Coil Program (LCP) is to demonstrate the reliable operation of large superconducting coils to provide a basis for the design principles, materials, and fabrication techniques proposed for the toroidal magnets for the THE NEXT STEP (TNS) and other future tokamak devices. This paper documents a design study of the Large Coil Test Facility (LCTF) in which the structural response of the Toroidal Field (TF) Coils and the supporting structure was evaluated under simulated reactor conditions. The LCP test facility structural system consists of six TF Coils, twelve coil-to-coil torsional restraining beams (torque rings), a central bucking post with base, and a Pulse Coil system. The NASTRAN Finite Element Structural Analysis computer Code was utilized to determine the distribution of deflections, forces, and stresses for each of the TF Coils, torque rings, and the central bucking post. Eleven load conditions were selected to represent probable test operations. Pulse Coils suspended in the bore of the test coil were energized to simulate the pulsed field environment characteristic of the TNS reactor system. The TORMAC Computer Code was utilized to develop the magnetic forces in the TF Coils for each of the eleven loading conditions examined, with or without the Pulse Coils energized. The TORMAC computer program output forces were used directly as input load conditions for the NASTRAN analyses. Results are presented which demonstrate the reliability of the LCTF under simulated reactor operating conditions

  13. SERPENTINE COIL TOPOLOGY FOR BNL DIRECT WIND SUPERCONDUCTING MAGNETS

    International Nuclear Information System (INIS)

    PARKER, B.; ESCALLIER, J.

    2005-01-01

    Serpentine winding, a recent innovation developed at BNL for direct winding superconducting magnets, allows winding a coil layer of arbitrary multipolarity in one continuous winding process and greatly simplifies magnet design and production compared to the planar patterns used before. Serpentine windings were used for the BEPC-II Upgrade and JPARC magnets and are proposed to make compact final focus magnets for the EC. Serpentine patterns exhibit a direct connection between 2D body harmonics and harmonics derived from the integral fields. Straightforward 2D optimization yields good integral field quality with uniformly spaced (natural) coil ends. This and other surprising features of Serpentine windings are addressed in this paper

  14. Ring Coils on the Endcap Yoke of a CLIC Detector

    CERN Document Server

    Gerwig, H

    2011-01-01

    Ring coils on the endcap return yoke can be useful in several ways. Depending on their size and the current chosen, they may either be used to reduce the fringe-field outside the return yoke of a detector, or to reduce considerably the thickness of the endcap yoke. The main focus of this note is the analysis of the ring coils, with the aim to reduce the overall length of the CLIC_ILD detector. In addition, some results concerning the fringe field in the vicinity of the detector are shown.

  15. Synthesis, model and stability of helically coiled carbon nanotubes

    DEFF Research Database (Denmark)

    Fejes, Dora; Raffai, Manuella; Hernadi, Klara

    2013-01-01

    . Our experiments focused on the production and development of catalysts for the synthesis of helically coiled CNTs (carbon nanotubes). The catalysts were tested in the decomposition of acetylene by CCVD (Catalytic Chemical Vapor Deposition) method. The carbon deposit was imaged by TEM (Transmission......Structural model of helically coiled carbon nanotubes is proposed. It is constructed by means of topological coordinate method. Relaxation and cohesive energy calculation are performed by molecular mechanics, using second-generation bond order potential for hydrocarbons introduced by D. W. Brenner...

  16. E-coil: an inverse boundary element method for a quasi-static problem

    International Nuclear Information System (INIS)

    Sanchez, Clemente Cobos; Garcia, Salvador Gonzalez; Power, Henry

    2010-01-01

    Boundary element methods represent a valuable approach for designing gradient coils; these methods are based on meshing the current carrying surface into an array of boundary elements. The temporally varying magnetic fields produced by gradient coils induce electric currents in conducting tissues and so the exposure of human subjects to these magnetic fields has become a safety concern, especially with the increase in the strength of the field gradients used in magnetic resonance imaging. Here we present a boundary element method for the design of coils that minimize the electric field induced in prescribed conducting systems. This work also details some numerical examples of the application of this coil design method. The reduction of the electric field induced in a prescribed region inside the coils is also evaluated.

  17. E-coil: an inverse boundary element method for a quasi-static problem

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Clemente Cobos; Garcia, Salvador Gonzalez [Depto. Electromagnetismo y F. de la Materia Facultad de Ciencias University of Granada Avda. Fuentenueva E-18071 (Spain); Power, Henry, E-mail: ccobos@ugr.e [School of Mechanical, Materials and Manufacturing Engineering, The University of Nottingham, Nottingham Park, Nottingham NG7 2RD (United Kingdom)

    2010-06-07

    Boundary element methods represent a valuable approach for designing gradient coils; these methods are based on meshing the current carrying surface into an array of boundary elements. The temporally varying magnetic fields produced by gradient coils induce electric currents in conducting tissues and so the exposure of human subjects to these magnetic fields has become a safety concern, especially with the increase in the strength of the field gradients used in magnetic resonance imaging. Here we present a boundary element method for the design of coils that minimize the electric field induced in prescribed conducting systems. This work also details some numerical examples of the application of this coil design method. The reduction of the electric field induced in a prescribed region inside the coils is also evaluated.

  18. Assessment of the microbiological safety of edible roasted nut kernels on retail sale in England, with a focus on Salmonella.

    Science.gov (United States)

    Little, C L; Jemmott, W; Surman-Lee, S; Hucklesby, L; de Pinnal, E

    2009-04-01

    There is little published information on the prevalence of Salmonella in edible nut kernels. A study in early 2008 of edible roasted nut kernels on retail sale in England was undertaken to assess the microbiological safety of this product. A total of 727 nut kernel samples of different varieties were examined. Overall, Salmonella and Escherichia coli were detected from 0.2 and 0.4% of edible roasted nut kernels. Of the nut varieties examined, Salmonella Havana was detected from 1 (4.0%) sample of pistachio nuts, indicating a risk to health. The United Kingdom Food Standards Agency was immediately informed, and full investigations were undertaken. Further examination established the contamination to be associated with the pistachio kernels and not the partly opened shells. Salmonella was not detected in other varieties tested (almonds, Brazils, cashews, hazelnuts, macadamia, peanuts, pecans, pine nuts, and walnuts). E. coli was found at low levels (range of 3.6 to 4/g) in walnuts (1.4%), almonds (1.2%), and Brazils (0.5%). The presence of Salmonella is unacceptable in edible nut kernels. Prevention of microbial contamination in these products lies in the application of good agricultural, manufacturing, and storage practices together with a hazard analysis and critical control points system that encompass all stages of production, processing, and distribution.

  19. Finite element coiled cochlea model

    Science.gov (United States)

    Isailovic, Velibor; Nikolic, Milica; Milosevic, Zarko; Saveljic, Igor; Nikolic, Dalibor; Radovic, Milos; Filipović, Nenad

    2015-12-01

    Cochlea is important part of the hearing system, and thanks to special structure converts external sound waves into neural impulses which go to the brain. Shape of the cochlea is like snail, so geometry of the cochlea model is complex. The simplified cochlea coiled model was developed using finite element method inside SIFEM FP7 project. Software application is created on the way that user can prescribe set of the parameters for spiral cochlea, as well as material properties and boundary conditions to the model. Several mathematical models were tested. The acoustic wave equation for describing fluid in the cochlea chambers - scala vestibuli and scala timpani, and Newtonian dynamics for describing vibrations of the basilar membrane are used. The mechanical behavior of the coiled cochlea was analyzed and the third chamber, scala media, was not modeled because it does not have a significant impact on the mechanical vibrations of the basilar membrane. The obtained results are in good agreement with experimental measurements. Future work is needed for more realistic geometry model. Coiled model of the cochlea was created and results are compared with initial simplified coiled model of the cochlea.

  20. BPX toroidal field coil design

    International Nuclear Information System (INIS)

    Heitzenvoeder, D.J.

    1992-01-01

    This paper reports on the toroidal field (TF) coil system of the Burning Plasma Experiment (BPX) which consists of (18) beryllium copper magnets arrayed in a wedged configuration with a major radius of 2.6 meters and a field strength capability on axis of 9.0 Tesla. The toroidal array is constructed from six (3)-coil modules to facilitate remote recovery in the event of a magnet failure after nuclear activation precludes hands-on servicing. The magnets are of a modified Bitter plate design with partial cases of type 316-LN stainless steel welded with Inconel 182 weld wire. The coil turn plates are fabricated from CDA C17510 beryllium copper with optimized mechanical, thermal, and electrical characteristics. joints within the turns and between turns are made by welding with C17200 filler wire. Cryogenic cooling is employed to reduce power dissipation and to enhance performance. The magnets are cooled between experimental pulses by pressurized liquid nitrogen flowing through channels in the edges of the coil turns. This arrangement makes possible one full-power pulse per hour. Electrical insulation consists of polyimide-glass sheets bonded in place with vacuum-pressure impregnated epoxy/glass

  1. Demonstration poloidal coil test facility

    International Nuclear Information System (INIS)

    Sato, Masahiko; Kawano, Katumi; Tada, Eisuke

    1989-01-01

    A new compact cryogenic cold compressor was developed by Japan Atomic Energy Research Institute (JAERI) in collaboration with Isikawajima-Harima Heavy Industries Co., Ltd. (IHI) in order to produce the supercritical helium below 4.2 K for Demonstration Poloidal Coils (DPC) which are forced-flow cooled type superconducting pulse coils. This compressor is one of key components for DPC test facility. The cold compressor reduces pressure in liquid helium bath, which contains liquid helium of around 3,000 l, down to 0.5 atm efficiently. Consequently, supercritical helium down to 3.5 K is produced and supplied to the DPC coils. A centrifugal compressor with dynamic gas bearing is selected as a compressor mechanism to realize high adiabatic efficiency and large flow rate. In this performance tests, the compressor was operated for 220 h at saturated condition from 0.5 to 1.0 atm without any failure. High adiabatic efficiency (more than 60 %) is achieved with wide flow range (25-65 g/s) and the design value is fully satisfied. The compressor can rotate up to 80,000 rpm at maximum then the coil supply temperature of supercritical helium is 3.5 K. (author)

  2. Open-Coil Retraction Spring

    Directory of Open Access Journals (Sweden)

    Pavankumar Janardan Vibhute

    2011-01-01

    Full Text Available Sliding mechanic has become a popular method for space closure with developments in preadjusted edgewise appliance. Furthermore, various space closing auxiliaries have been developed and evaluated extensively for their clinical efficiency. Their effectiveness enhanced with optimum force magnitude and low-load deflection rate (LDR/force decay. With the advent of NiTi springs in orthodontics, LDRs have been markedly reduced. For use of NiTi, clinician has to depend upon prefabricated closed coil springs. “Open Coil Retraction Spring (OCRS” is developed utilizing NiTi open-coil spring for orthodontic space closure. This paper describes fabrication and clinical application of OCRS which have number of advantages. It sustains low LDR with optimum force magnitude. Its design is adjustable for desired length and force level. It is fail-safe for both activation and deactivation (i.e., it cannot be over activated, and decompression limit of open coil is also controlled by the operator, resp.. A possibility to offset the OCRS away from mucosa helps to reduce its soft-tissue impingement.

  3. PDX toroidal field coils stress analysis

    International Nuclear Information System (INIS)

    Nikodem, Z.D.; Smith, R.A.

    1975-01-01

    A method used in the stress analysis of the PDX toroidal field coil is developed. A multilayer coil design of arbitrary dimensions in the shape of either a circle or an oval is considered. The analytical model of the coil and the supporting coil case with connections to the main support structure is analyzed using the finite element technique. The three dimensional magnetic fields and the non-uniform body forces which are a loading condition on a coil due to toroidal and poloidal fields are calculated. The method of analysis permits rapid and economic evaluations of design changes in coil geometry as well as in coil support structures. Some results pertinent to the design evolution and their comparison are discussed. The results of the detailed stress analysis of the final coil design due to toroidal field, poloidal field and temperature loads are presented

  4. Design of a surface-scanning coil detector for direct bacteria detection on food surfaces using a magnetoelastic biosensor

    Science.gov (United States)

    Chai, Yating; Wikle, Howard C.; Wang, Zhenyu; Horikawa, Shin; Best, Steve; Cheng, Zhongyang; Dyer, Dave F.; Chin, Bryan A.

    2013-09-01

    The real-time, in-situ bacteria detection on food surfaces was achieved by using a magnetoelastic biosensor combined with a surface-scanning coil detector. This paper focuses on the coil design for signal optimization. The coil was used to excite the sensor's vibration and detect its resonant frequency signal. The vibrating sensor creates a magnetic flux change around the coil, which then produces a mutual inductance. In order to enhance the signal amplitude, a theory of the sensor's mutual inductance with the measurement coil is proposed. Both theoretical calculations and experimental data showed that the working length of the coil has a significant effect on the signal amplitude. For a 1 mm-long sensor, a coil with a working length of 1.3 mm showed the best signal amplitude. The real-time detection of Salmonella bacteria on a fresh food surface was demonstrated using this new technology.

  5. Bow-shaped toroidal field coils

    International Nuclear Information System (INIS)

    Bonanos, P.

    1981-05-01

    Design features of Bow-Shaped Toroidal Field Coils are described and compared with circular and D shaped coils. The results indicate that bow coils can produce higher field strengths, store more energy and be made demountable. The design offers the potential for the production of ultrahigh toroidal fields. Included are representative coil shapes and their engineering properties, a suggested structural design and an analysis of a specific case

  6. Design and modelling of a SMES coil

    Energy Technology Data Exchange (ETDEWEB)

    Yuan Weijia; Campbell, A M; Coombs, T A, E-mail: wy215@cam.ac.u [EPEC Superconductivity group, Engineering Department, 9 JJ Thomson Avenue, Cambridge, CB3 0FA (United Kingdom)

    2010-06-01

    The design of a Superconducting Magnetic Energy Storage (SMES) coil wound by coated conductors has been presented. Based on an existing model for coated conductor pancake coils, this paper analysed the magnetic field and current density distribution of the coil at two different operation temperatures, 77K and 22K. A comparison table of the critical currents and AC losses at these two temperatures has been presented. Several steps to improve the transport current of the coil have been suggested as well.

  7. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

    DEFF Research Database (Denmark)

    Céspedes, Nora; Habel, Catherine; Lopez-Perez, Mary

    2014-01-01

    Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Pla...

  8. Sensitive quench detection of the HTS coil using a co-winding coil

    International Nuclear Information System (INIS)

    Takagi, Tomohiro; Ariyama, Takahiro; Takao, Tomoaki; Tsukamoto, Osami

    2017-01-01

    The authors have studied the co-winding coil method (CW method) using the co-wound coil electrically insulated from the HTS coil. In this method, the quench is detected by the voltage difference between the coil of the HTS tape (HTS coil) and the coil of the normal conductor (CW coil). The voltage induced in the CW coil caused by the change of the magnetic field is almost the same as that in the HTS coil because the coils are magnetically coupled close to each other. Therefore, it is expected that the induced voltage will be canceled with high accuracy and that the resistive voltage in the HTS coil will be detected with greater sensitivity compared to the bridge balance method, which is used commonly. In this study, quench detection applying the CW method is demonstrated using an experimental double-pancake coil. A tape with the copper layer deposited on the polymer substrate was used as the insulated conductor wire to form the CW coil. An additional pancake coil was used to expose the experimental double-pancake coil to the external magnetic field asymmetrically. It was shown that the CW method can detect the resistive voltage with greater sensitivity even when the HTS coil was exposed to the changing asymmetric external magnetic field. (author)

  9. Status of the Swiss LCT-coil

    International Nuclear Information System (INIS)

    Zichy, J; Benz, H.; Horvath, I.; Jakob, B.; Marinucci, C.; Vecsey, G.; Weymuth, P.; Zellweger, J.

    1983-01-01

    The Swiss coil is a forced flow coil cooled by supercritical helium. A brief review of the design considerations, some of its specific features, and the progress in fabrication are described. A discussion of both the instrumentation and the cryogenic characteristics of the coil is presented

  10. Linear motor coil assembly and linear motor

    NARCIS (Netherlands)

    2009-01-01

    An ironless linear motor (5) comprising a magnet track (53) and a coil assembly (50) operating in cooperation with said magnet track (53) and having a plurality of concentrated multi-turn coils (31 a-f, 41 a-d, 51 a-k), wherein the end windings (31E) of the coils (31 a-f, 41 a-e) are substantially

  11. Split Coil Forms for Rotary Transformers

    Science.gov (United States)

    Mclyman, C. W. T.

    1982-01-01

    Split cores for rotor and stator windings of rotary transformer mounted around their respective coils (which are in bobbins) and cemented together. This arrangement simplifies winding of stator coil to go in a slot in inner diameter of stator coil. One practical application of rotary transformers fabricated according to this technique is for centrifuges, in which conventional sliprings are of uncertain reliability.

  12. Startup of large coil test facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1984-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils. (author)

  13. Novel method of aligning ATF-1 coils

    International Nuclear Information System (INIS)

    Rome, J.A.; Harris, J.H.; Neilson, G.H.; Jernigan, T.C.

    1983-08-01

    The coils for the Advanced Toroidal Facility (ATF-1) torsatron may be easily aligned before the machine is placed under vacuum. This is done by creating nulls in the magnetic field by energizing the coils in various configurations. All of the nulls in vertical bar B vector vertical bar occur on the z-axis. When the nulls coincide, the coils are properly aligned

  14. Self-Assembly of Rod-Coil Block Copolymers

    National Research Council Canada - National Science Library

    Jenekhe, S

    1999-01-01

    ... the self-assembly of new rod-coil diblock, rod- coil-rod triblock, and coil-rod-coil triblock copolymers from solution and the resulting discrete and periodic mesostmctares with sizes in the 100...

  15. Efficacy and safety of eco-friendly inhalers: focus on combination ipratropium bromide and albuterol in chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Panos RJ

    2013-04-01

    can achieve effects equivalent to pMDIs but with lower medication doses. The long-term safety and efficacy remain to be determined. The Respimat SMI delivery device is a novel, efficient, and well-received system for the delivery of aerosolized albuterol and ipratropium bromide to patients with COPD; however, the presence of longer-acting, less frequently dosed respiratory medications provide patients and providers with other therapeutic options. Keywords: Respimat® Soft Mist Inhaler™, COPD, pressurized metered-dose inhaler, chlorofluorocarbons

  16. The efficacy and safety of intense focused ultrasound in the treatment of enlarged facial pores in Asian skin.

    Science.gov (United States)

    Lee, Hee Jung; Lee, Kyung Real; Park, Jae Yang; Yoon, Moon Soo; Lee, Sang Eun

    2015-02-01

    Intense focused ultrasound (IFUS) has been used successfully for skin tightening. To investigate the efficacy of IFUS in treating enlarged pores and to evaluate changes in skin elasticity and sebum production following IFUS. Twenty-two subjects with enlarged pores were randomized to receive a single treatment with IFUS using 1.5-mm transducer on one side of the face, and 3.0-mm transducer on the other. OBJECTIVE clinical assessments were made by blinded photographic evaluation. Subjective satisfaction and adverse effects were evaluated. Measurements of elasticity and sebum were performed at baseline, 3 and 6 weeks post-treatment. Physicians' evaluation showed clinical pore improvements in 86% and 91% of the IFUS-treated sites using 1.5-mm and 3.0-mm transducer, respectively. The mean improvement scores were 1.7 and 1.9 for 1.5-mm and 3.0-mm transducer, respectively, with no statistical differences. Cutometer measurement demonstrated a significant improvement in skin elasticity. Sebum level showed a reduction without statistical significance. There was a positive correlation between improvement in elasticity and pore improvement grades. All treatments were well tolerated without significant side effects. IFUS using 1.5-mm or 3.0-mm transducer was safe and effective for reducing enlarged pores in Asian skin with an improvement in skin elasticity.

  17. Coil Migration through a Neuroform 3 Stent during Endovascular Coiling. A Case Report.

    LENUS (Irish Health Repository)

    O'Hare, A

    2009-07-29

    Summary: A 43-year-old woman attended for stent assisted coiling. A Neuroform 30 x 4.5 mm stent had been successfully placed over the left periophthalmic aneurysm. During the coiling the first coil migrated through the crowns in the stent, lodging at the MCA bifurcation. We believe that the coil herniated through the overlying stent due to the carotid siphon curvature and the open cell design. Furthermore the distal markers of the stent impeded coil extraction with a MERCI device.

  18. An inflatable surface coil for rectal imaging

    International Nuclear Information System (INIS)

    Martin, J.F.; Hajek, P.C.; Baker, L.L.; Gylys-Morin, V.; Mattrey, R.F.

    1986-01-01

    Surface coils have become ubiquitous in MR imaging of the body because of substantial gains in signal-to-noise ratio. Unfortunately, there are some anatomic regions, such as the prostate, for which surface coils have insufficient depth sensitivity. The authors have developed an inflatable, distributed capacitance, passively decoupled surface coil which is collapsed for insertion and reinflated for imaging. Images of the prostate are dramatically improved due to proximity of the coil. Lesions in cadaver specimens were observed which were not seen with body coil imaging. Clinical trials are expected to begin in September

  19. Design and simulation of printed spiral coil used in wireless power transmission systems for implant medical devices.

    Science.gov (United States)

    Wu, Wei; Fang, Qiang

    2011-01-01

    Printed Spiral Coil (PSC) is a coil antenna for near-field wireless power transmission to the next generation implant medical devices. PSC for implant medical device should be power efficient and low electromagnetic radiation to human tissues. We utilized a physical model of printed spiral coil and applied our algorithm to design PSC operating at 13.56 MHz. Numerical and electromagnetic simulation of power transfer efficiency of PSC in air medium is 77.5% and 71.1%, respectively. The simulation results show that the printed spiral coil which is optimized for air will keep 15.2% power transfer efficiency in human subcutaneous tissues. In addition, the Specific Absorption Ratio (SAR) for this coil antenna in subcutaneous at 13.56 MHz is below 1.6 W/Kg, which suggests this coil is implantable safe based on IEEE C95.1 safety guideline.

  20. SAFETY

    CERN Multimedia

    C. Schaefer and N. Dupont

    2013-01-01

      “Safety is the highest priority”: this statement from CERN is endorsed by the CMS management. An interpretation of this statement may bring you to the conclusion that you should stop working in order to avoid risks. If the safety is the priority, work is not! This would be a misunderstanding and misinterpretation. One should understand that “working safely” or “operating safely” is the priority at CERN. CERN personnel are exposed to different hazards on many levels on a daily basis. However, risk analyses and assessments are done in order to limit the number and the gravity of accidents. For example, this process takes place each time you cross the road. The hazard is the moving vehicle, the stake is you and the risk might be the risk of collision between both. The same principle has to be applied during our daily work. In particular, keeping in mind the general principles of prevention defined in the late 1980s. These principles wer...

  1. Equilibrium modeling of the TFCX poloidal field coil system

    International Nuclear Information System (INIS)

    Strickler, D.J.; Miller, J.B.; Rothe, K.E.; Peng, Y.K.M.

    1984-04-01

    The Toroidal Fusion Core Experiment (TFCX) isproposed to be an ignition device with a low safety factor (q approx. = 2.0), rf or rf-assisted startup, long inductive burn pulse (approx. 300 s), and an elongated plasma cross section (kappa = 1.6) with moderate triangularity (delta = 0.3). System trade studies have been carried out to assist in choosing an appropriate candidate for TFCX conceptual design. This report describes an important element in these system studies - the magnetohydrodynamic (MHD) equilibrium modeling of the TFCX poloidal field (PF) coil system and its impact on the choice of machine size. Reference design points for the all-super-conducting toroidal field (TF) coil (TFCX-S) and hybrid (TFCX-H) options are presented that satisfy given PF system criteria, including volt-second requirements during burn, mechanical configuration constraints, maximum field constraints at the superconducting PF coils, and plasma shape parameters. Poloidal coil current waveforms for the TFCX-S and TFCX-H reference designs consistent with the equilibrium requirements of the plasma startup, heating, and burn phases of a typical discharge scenario are calculated. Finally, a possible option for quasi-steady-state operation is discussed

  2. ANL experimental program for pulsed superconducting coils

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.; Praeg, W.F.; Krieger, C.I.

    1978-01-01

    Argonne National Laboratory (ANL) had recognized the clear advantage of a superconducting ohmic-heating (OH) coil and started in aggressive development program in FY 1977. The main objectives for FY 1977 are to develop cryostable basic cable configurations with reasonably low ac losses, to develop 12 kA cryostable cable, using it to design and build a 1.5 MJ pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat for the 1.5 MJ pulsed coil. The principal objective in building the 1.5 MJ ac coil is to demonstrate ac cryostability of a large coil ranging from 2 T/s up to 12 T/s. Another objective in the pulsed coil program is to determine the feasibility of parallel coil operation in order to avoid excessive voltage and current requirements and to minimize the number of turns for the equilibrium field (EF) coils, should the EF coils be connected in parallel with the OH coils. A two-coil section model using the 11 kA cable will be built and tested

  3. Pulse coil concepts for the LCP Facility

    International Nuclear Information System (INIS)

    Nelson, B.E.; Burn, P.B.

    1977-01-01

    The pulse coils described in this paper are resistive copper magnets driven by time-varying currents. They are included in the Large Coil Test Facility (LCTF) portion of the Large Coil Program (LCP) to simulate the pulsed field environment of the toroidal coils in a tokamak reactor. Since TNS (a 150 sec, 5MA, igniting tokamak) and the Oak Ridge EPR (Experimental Power Reactor) are representative of the first tokamaks to require the technology developed in LCP, the reference designs for these machines, especially TNS, are used to derive the magnetic criteria for the pulse coils. This criteria includes the magnitude, distribution, and rate of change of pulsed fields in the toroidal coil windings. Three pulse coil concepts are evaluated on the basis of magnetic criteria and factors such as versatility of design, ease of fabrication and cost of operation. The three concepts include (1) a pair of poloidal coils outside the LCTF torus, (2) a single poloidal coil threaded through the torus, and (3) a pair of vertical axis coil windings inside the bore of one or more of the toroidal test coils

  4. ANL experimental program for pulsed superconducting coils

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.; Praeg, W.F.; Krieger, C.I.

    1977-01-01

    Argonne National Laboratory (ANL) had recognized the clear advantage of a superconducting ohmic-heating (OH) coil and started an aggressive development program in FY 1977. The main objectives for FY 1977 are to develop cryostable basic cable configurations with reasonably low ac losses, to develop 12 kA cryostable cable, using it to design and build a 1.5 MJ pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat for the 1.5 MJ pulsed coil. The principal objective in building the 1.5 MJ ac coil is to demonstrate ac cryostability of a large coil ranging from 2 T/s up to 12 T/s. Another objective in the pusled coil program is to determine the feasibility of parallel coil operation in order to avoid excessive voltage and current requirements and to minimize the number of turns for the equilibrium field (EF) coils, should the EF coils be connected in parallel with the OH coils. A two-coil section model using the 11 kA cable will be built and tested

  5. Performance evaluation of matrix gradient coils.

    Science.gov (United States)

    Jia, Feng; Schultz, Gerrit; Testud, Frederik; Welz, Anna Masako; Weber, Hans; Littin, Sebastian; Yu, Huijun; Hennig, Jürgen; Zaitsev, Maxim

    2016-02-01

    In this paper, we present a new performance measure of a matrix coil (also known as multi-coil) from the perspective of efficient, local, non-linear encoding without explicitly considering target encoding fields. An optimization problem based on a joint optimization for the non-linear encoding fields is formulated. Based on the derived objective function, a figure of merit of a matrix coil is defined, which is a generalization of a previously known resistive figure of merit for traditional gradient coils. A cylindrical matrix coil design with a high number of elements is used to illustrate the proposed performance measure. The results are analyzed to reveal novel features of matrix coil designs, which allowed us to optimize coil parameters, such as number of coil elements. A comparison to a scaled, existing multi-coil is also provided to demonstrate the use of the proposed performance parameter. The assessment of a matrix gradient coil profits from using a single performance parameter that takes the local encoding performance of the coil into account in relation to the dissipated power.

  6. Optimization of Moving Coil Actuators for Digital Displacement Machines

    DEFF Research Database (Denmark)

    Nørgård, Christian; Bech, Michael Møller; Roemer, Daniel Beck

    2016-01-01

    This paper focuses on deriving an optimal moving coil actuator design, used as force pro-ducing element in hydraulic on/off valves for Digital Displacement machines. Different moving coil actuator geometry topologies (permanent magnet placement and magnetiza-tion direction) are optimized for actu......This paper focuses on deriving an optimal moving coil actuator design, used as force pro-ducing element in hydraulic on/off valves for Digital Displacement machines. Different moving coil actuator geometry topologies (permanent magnet placement and magnetiza-tion direction) are optimized...... for actuating annular seat valves in a digital displacement machine. The optimization objectives are to the minimize the actuator power, the valve flow losses and the height of the actuator. Evaluation of the objective function involves static finite element simulation and simulation of an entire operation...... designs requires approximately 20 W on average and may be realized in 20 mm × Ø 22.5 mm (height × diameter) for a 20 kW pressure chamber. The optimization is carried out using the multi-objective Generalized Differential Evolu-tion optimization algorithm GDE3 which successfully handles constrained multi-objective...

  7. Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety.

    Science.gov (United States)

    Meanwell, Nicholas A

    2011-09-19

    The development of small molecule drug candidates from the discovery phase to a marketed product continues to be a challenging enterprise with very low success rates that have fostered the perception of poor productivity by the pharmaceutical industry. Although there have been significant advances in preclinical profiling that have improved compound triaging and altered the underlying reasons for compound attrition, the failure rates have not appreciably changed. As part of an effort to more deeply understand the reasons for candidate failure, there has been considerable interest in analyzing the physicochemical properties of marketed drugs for the purpose of comparing with drugs in discovery and development as a means capturing recent trends in drug design. The scenario that has emerged is one in which contemporary drug discovery is thought to be focused too heavily on advancing candidates with profiles that are most easily satisfied by molecules with increased molecular weight and higher overall lipophilicity. The preponderance of molecules expressing these properties is frequently a function of increased aromatic ring count when compared with that of the drugs launched in the latter half of the 20th century and may reflect a preoccupation with maximizing target affinity rather than taking a more holistic approach to drug design. These attributes not only present challenges for formulation and absorption but also may influence the manifestation of toxicity during development. By providing some definition around the optimal physicochemical properties associated with marketed drugs, guidelines for drug design have been developed that are based largely on calculated parameters and which may readily be applied by medicinal chemists as an aid to understanding candidate quality. The physicochemical properties of a molecule that are consistent with the potential for good oral absorption were initially defined by Lipinski, with additional insights allowing further

  8. Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood-brain barrier disruption: a safety study.

    Science.gov (United States)

    Aryal, Muna; Vykhodtseva, Natalia; Zhang, Yong-Zhi; McDannold, Nathan

    2015-04-28

    Transcranial MRI-guided focused ultrasound is a rapidly advancing method for delivering therapeutic and imaging agents to the brain. It has the ability to facilitate the passage of therapeutics from the vasculature to the brain parenchyma, which is normally protected by the blood-brain barrier (BBB). The method's main advantages are that it is both targeted and noninvasive, and that it can be easily repeated. Studies have shown that liposomal doxorubicin (Lipo-DOX), a chemotherapy agent with promise for tumors in the central nervous system, can be delivered into the brain across BBB. However, prior studies have suggested that doxorubicin can be significantly neurotoxic, even at small concentrations. Here, we studied whether multiple sessions of Lipo-DOX administered after FUS-induced BBB disruption (FUS-BBBD) induces severe adverse events in the normal brain tissues. First, we used fluorometry to measure the doxorubicin concentrations in the brain after FUS-BBBD to ensure that a clinically relevant doxorubicin concentration was achieved in the brain. Next, we performed three weekly sessions with FUS-BBBD±Lipo-DOX administration. Five to twelve targets were sonicated each week, following a schedule described previously in a survival study in glioma-bearing rats (Aryal et al., 2013). Five rats received three weekly sessions where i.v. injected Lipo-DOX was combined with FUS-BBBD; an additional four rats received FUS-BBBD only. Animals were euthanized 70days from the first session and brains were examined in histology. We found that clinically-relevant concentrations of doxorubicin (4.8±0.5μg/g) were delivered to the brain with the sonication parameters (0.69MHz; 0.55-0.81MPa; 10ms bursts; 1Hz PRF; 60s duration), microbubble concentration (Definity, 10μl/kg), and the administered Lipo-DOX dose (5.67mg/kg) used. The resulting concentration of Lipo-DOX was reduced by 32% when it was injected 10min after the last sonication compared to cases where the agent was

  9. Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema : The RENEW Randomized Clinical Trial

    NARCIS (Netherlands)

    Sciurba, Frank C.; Criner, Gerard J.; Strange, Charlie; Shah, Pallav L.; Michaud, Gaetane; Connolly, Timothy A.; Deslee, Gaetan; Tillis, William P.; Delage, Antoine; Marquette, Charles-Hugo; Krishna, Ganesh; Kalhan, Ravi; Ferguson, J. Scott; Jantz, Michael; Maldonado, Fabien; McKenna, Robert; Majid, Adnan; Rai, Navdeep; Gay, Steven; Dransfield, Mark T.; Angel, Luis; Maxfield, Roger; Herth, Felix J. F.; Wahidi, Momen M.; Mehta, Atul; Slebos, Dirk-Jan

    2016-01-01

    IMPORTANCE Preliminary clinical trials have demonstrated that endobronchial coils compress emphysematous lung tissue and may improve lung function, exercise tolerance, and symptoms in patients with emphysema and severe lung hyperinflation. OBJECTIVE To determine the effectiveness and safety of

  10. Coiled transmission line pulse generators

    Science.gov (United States)

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  11. Safety

    International Nuclear Information System (INIS)

    Jones, P.M.S.

    1987-01-01

    Aspects of fission reactors are considered - control, heat removal and containment. Brief descriptions of the reactor accidents at the SL-1 reactor (1961), Windscale (1957), Browns Ferry (1975), Three Mile Island (1979) and Chernobyl (1986) are given. The idea of inherently safe reactor designs is discussed. Safety assessment is considered under the headings of preliminary hazard analysis, failure mode analysis, event trees, fault trees, common mode failure and probabalistic risk assessments. These latter can result in a series of risk distributions linked to specific groups of fault sequences and specific consequences. A frequency-consequence diagram is shown. Fatal accident incidence rates in different countries including the United Kingdom for various industries are quoted. The incidence of fatal cancers from occupational exposure to chemicals is tabulated. Human factors and the acceptability of risk are considered. (U.K.)

  12. Design of an 18 Tesla, tandem mirror, fusion reactor, hybrid choke coil

    International Nuclear Information System (INIS)

    Parmer, J.F.; Agarwal, K.; Gurol, H.; Mancuso, A.; Michels, P.H.; Peck, S.D.; Burgeson, J.; Dalder, E.N.

    1987-01-01

    A hybrid, part normal part superconducting 18-Tesla solenoid choke coil is designed for a tandem mirror fusion reactor. The present state of the art is represented by the 12-Tesla, superconducting NbSn coil. Future applications other than tandem mirror fusion devices needing high field solenoids might require hybrid magnets of the type described herein. The hybrid design was generated because of critical field performance limitations on present, practical superconducting wires. A hybrid design might be required (due to structural limits) even if the critical field were higher. Also, hybrids could be a cost-effective way of getting very high fields for certain applications. The 18-Tesla solenoid described is composed of an inner coil made of water-cooled, high-strength zirconium copper which generates 3 Tesla. A superconducting NbSn background coil contributes the remaining 15 Tesla. The focus of the design study was on the inner coil. Demonstration fabrication and testing was performed

  13. Conformational switching in the coiled-coil domains of a proteasomal ATPase regulates substrate processing.

    Science.gov (United States)

    Snoberger, Aaron; Brettrager, Evan J; Smith, David M

    2018-06-18

    Protein degradation in all domains of life requires ATPases that unfold and inject proteins into compartmentalized proteolytic chambers. Proteasomal ATPases in eukaryotes and archaea contain poorly understood N-terminally conserved coiled-coil domains. In this study, we engineer disulfide crosslinks in the coiled-coils of the archaeal proteasomal ATPase (PAN) and report that its three identical coiled-coil domains can adopt three different conformations: (1) in-register and zipped, (2) in-register and partially unzipped, and (3) out-of-register. This conformational heterogeneity conflicts with PAN's symmetrical OB-coiled-coil crystal structure but resembles the conformational heterogeneity of the 26S proteasomal ATPases' coiled-coils. Furthermore, we find that one coiled-coil can be conformationally constrained even while unfolding substrates, and conformational changes in two of the coiled-coils regulate PAN switching between resting and active states. This switching functionally mimics similar states proposed for the 26S proteasome from cryo-EM. These findings thus build a mechanistic framework to understand regulation of proteasome activity.

  14. Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3

    International Nuclear Information System (INIS)

    Amano, Yosuke; Ishikawa, Rie; Sakatani, Toshio; Ichinose, Junji; Sunohara, Mitsuhiro; Watanabe, Kousuke; Kage, Hidenori; Nakajima, Jun; Nagase, Takahide; Ohishi, Nobuya; Takai, Daiya

    2015-01-01

    Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can arise from anywhere in the body. Anaplastic lymphoma kinase (ALK) gene rearrangements, most often resulting in the tropomyosin 3 (TPM3)-ALK fusion gene, are the main causes of IMT. However, the mechanism of malignant transformation in IMT has yet to be elucidated. The purpose of this study was to clarify the role of the TPM3 region in the transformation of IMT via TPM3-ALK. Lentivirus vectors containing a TPM3-ALK fusion gene lacking various lengths of TPM3 were constructed and expressed in HEK293T and NIH3T3 cell lines. Focus formation assay revealed loss of contact inhibition in NIH3T3 cells transfected with full-length TPM3-ALK, but not with ALK alone. Blue-native polyacrylamide gel electrophoresis (BN-PAGE) revealed that TPM3-ALK dimerization increased in proportion to the length of TPM3. Western blot showed phosphorylation of ALK, ERK1/2, and STAT3 in HEK293T cells transfected with TPM3-ALK. Thus, the coiled-coil structure of TPM3 contributes to the transforming ability of the TPM3-ALK fusion protein, and longer TPM3 region leads to higher dimer formation. - Highlights: • TPM3-ALK fusion protein dimerizes through the coiled-coil structure of TPM3. • Longer coiled-coil structure of TPM3 leads to higher TPM3-ALK dimer formation. • Presence of TPM3-ALK dimer leads to ALK, STAT3, and ERK1/2 phosphorylation. • Presence of TPM3-ALK leads to loss of contact inhibition. • BN-PAGE is a simple technique for visualizing oncogenic dimerization

  15. Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3

    Energy Technology Data Exchange (ETDEWEB)

    Amano, Yosuke; Ishikawa, Rie; Sakatani, Toshio [Department of Respiratory Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Ichinose, Junji [Department of Cardiothoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Sunohara, Mitsuhiro; Watanabe, Kousuke; Kage, Hidenori [Department of Respiratory Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Nakajima, Jun [Department of Cardiothoracic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Nagase, Takahide; Ohishi, Nobuya [Department of Respiratory Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Takai, Daiya, E-mail: dtakai-ind@umin.ac.jp [Department of Respiratory Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Department of Clinical Laboratory, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan)

    2015-02-13

    Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can arise from anywhere in the body. Anaplastic lymphoma kinase (ALK) gene rearrangements, most often resulting in the tropomyosin 3 (TPM3)-ALK fusion gene, are the main causes of IMT. However, the mechanism of malignant transformation in IMT has yet to be elucidated. The purpose of this study was to clarify the role of the TPM3 region in the transformation of IMT via TPM3-ALK. Lentivirus vectors containing a TPM3-ALK fusion gene lacking various lengths of TPM3 were constructed and expressed in HEK293T and NIH3T3 cell lines. Focus formation assay revealed loss of contact inhibition in NIH3T3 cells transfected with full-length TPM3-ALK, but not with ALK alone. Blue-native polyacrylamide gel electrophoresis (BN-PAGE) revealed that TPM3-ALK dimerization increased in proportion to the length of TPM3. Western blot showed phosphorylation of ALK, ERK1/2, and STAT3 in HEK293T cells transfected with TPM3-ALK. Thus, the coiled-coil structure of TPM3 contributes to the transforming ability of the TPM3-ALK fusion protein, and longer TPM3 region leads to higher dimer formation. - Highlights: • TPM3-ALK fusion protein dimerizes through the coiled-coil structure of TPM3. • Longer coiled-coil structure of TPM3 leads to higher TPM3-ALK dimer formation. • Presence of TPM3-ALK dimer leads to ALK, STAT3, and ERK1/2 phosphorylation. • Presence of TPM3-ALK leads to loss of contact inhibition. • BN-PAGE is a simple technique for visualizing oncogenic dimerization.

  16. Remote maintenance of tandem mirror hybrid coils

    International Nuclear Information System (INIS)

    Dietz, L.P.

    1983-01-01

    Hybrid Coils (superconducting coils with normal conducting inserts) are being employed with increasing frequency on Tandem Mirror Devices to obtain high field strengths. The normal conducting copper inserts are short lived in comparison to their encircling superconductors. It becomes desirable, therefore, to devise design features and maintenance procedures to replace the inner normal conducting coils without simultaneously replacing the longer lived (and significantly more costly) superconducting coils. The high neutron wall loadings require that the task be accomplished by remote control. The approach is to permanently mount the coil assemblies on track mounted carriages which serve, during machine operation merely as structural supports, but during maintenance procedures as moveable transport devices. The carriages incorporate all necessary provisions to facilitate remote maintenance operations and to adjust and align the coil assemblies with respect to adjacent machine components. The vacuum vessel is severed on both sides of the hybrid coil by means of a remote cutting machine. The entire coil is transported horizontally, normal to the machine axis to a nearby repair station. Prepositioned carriage mounted repair equipment at the repair station withdraws the damaged normal coil as a single entity and inserts a preassembled spare unit. The repaired hybrid coil is reassembled to the reactor. A cost and risk effective procedure has been evolved to maintain one of the more critical components of a Tandem Mirror Machine

  17. Discussion of discrete D shape toroidal coil

    International Nuclear Information System (INIS)

    Kaiho, Katsuyuki; Ohara, Takeshi; Agatsuma, Ko; Onishi, Toshitada

    1988-01-01

    A novel design for a toroidal coil, called the D shape coil, was reported by J. File. The coil conductors are in pure tension and then subject to no bending moment. This leads to a smaller number of emf supports in a simpler configuration than that with the conventional toroidal coil of circular cross-section. The contours of the D shape are given as solutions of a differential equation. This equation includes the function of the magnetic field distribution in the conductor region which is inversely proportional to the winding radius. It is therefore important to use the exact magnetic field distribution. However the magnetic field distribution becomes complicated when the D shape toroidal coil is comprised of discrete coils and also depends on the D shape configuration. A theory and a computer program for designing the practical pure-tension toroidal coil are developed. Using this computer code, D shape conductors are calculated for various numbers of discrete coils and the results are compared. Electromagnetic forces in the coils are also calculated. It is shown that the hoop stress in the conductors depends only on the total ampere-turns of the coil when the contours of the D shape are similar. (author)

  18. Large coil test facility conceptual design report

    International Nuclear Information System (INIS)

    Nelms, L.W.; Thompson, P.B.; Mann, T.L.

    1978-02-01

    In the development of a superconducting toroidal field (TF) magnet for The Next Step (TNS) tokamak reactor, several different TF coils, about half TNS size, will be built and tested to permit selection of a design and fabrication procedure for full-scale TNS coils. A conceptual design has been completed for a facility to test D-shaped TF coils, 2.5 x 3.5-m bore, operating at 4-6 K, cooled either by boiling helium or by forced-flow supercritical helium. Up to six coils can be accommodated in a toroidal array housed in a single vacuum tank. The principal components and systems in the facility are an 11-m vacuum tank, a test stand providing structural support and service connections for the coils, a liquid nitrogen system, a system providing helium both as saturated liquid and at supercritical pressure, coils to produce a pulsed vertical field at any selected test coil position, coil power supplies, process instrumentation and control, coil diagnostics, and a data acquisition and handling system. The test stand structure is composed of a central bucking post, a base structure, and two horizontal torque rings. The coils are bolted to the bucking post, which transmits all gravity loads to the base structure. The torque ring structure, consisting of beams between adjacent coils, acts with the bucking structure to react all the magnetic loads that occur when the coils are energized. Liquid helium is used to cool the test stand structure to 5 K to minimize heat conduction to the coils. Liquid nitrogen is used to precool gaseous helium during system cooldown and to provide thermal radiation shielding

  19. Focusing on Contact Lens Safety

    Science.gov (United States)

    ... their practices. Decorative contacts (also called “costume,” colored,” “fashion,” or “plano” contacts). The FDA has often warned ... Lenses Decorative Contact Lenses Hydrogen Peroxide Solution Related Consumer Updates 'Colored' and Decorative Contact Lenses: A Prescription ...

  20. Safety and Efficacy of Focused Ultrasound Thalamotomy for Patients With Medication-Refractory, Tremor-Dominant Parkinson Disease: A Randomized Clinical Trial.

    Science.gov (United States)

    Bond, Aaron E; Shah, Binit B; Huss, Diane S; Dallapiazza, Robert F; Warren, Amy; Harrison, Madaline B; Sperling, Scott A; Wang, Xin-Qun; Gwinn, Ryder; Witt, Jennie; Ro, Susie; Elias, W Jeffrey

    2017-12-01

    Clinical trials have confirmed the efficacy of focused ultrasound (FUS) thalamotomy in essential tremor, but its effectiveness and safety for managing tremor-dominant Parkinson disease (TDPD) is unknown. To assess safety and efficacy at 12-month follow-up, accounting for placebo response, of unilateral FUS thalamotomy for patients with TDPD. Of the 326 patients identified from an in-house database, 53 patients consented to be screened. Twenty-six were ineligible, and 27 were randomized (2:1) to FUS thalamotomy or a sham procedure at 2 centers from October18, 2012, to January 8, 2015. The most common reasons for disqualification were withdrawal (8 persons [31%]), and not being medication refractory (8 persons [31%]). Data were analyzed using intention-to-treat analysis, and assessments were double-blinded through the primary outcome. Twenty patients were randomized to unilateral FUS thalamotomy, and 7 to sham procedure. The sham group was offered open-label treatment after unblinding. The predefined primary outcomes were safety and difference in improvement between groups at 3 months in the on-medication treated hand tremor subscore from the Clinical Rating Scale for Tremor (CRST). Secondary outcomes included descriptive results of Unified Parkinson's Disease Rating Scale (UPDRS) scores and quality of life measures. Of the 27 patients, 26 (96%) were male and the median age was 67.8 years (interquartile range [IQR], 62.1-73.8 years). On-medication median tremor scores improved 62% (IQR, 22%-79%) from a baseline of 17 points (IQR, 10.5-27.5) following FUS thalamotomy and 22% (IQR, -11% to 29%) from a baseline of 23 points (IQR, 14.0-27.0) after sham procedures; the between-group difference was significant (Wilcoxon P = .04). On-medication median UPDRS motor scores improved 8 points (IQR, 0.5-11.0) from a baseline of 23 points (IQR, 15.5-34.0) following FUS thalamotomy and 1 point (IQR, -5.0 to 9.0) from a baseline of 25 points (IQR, 15.0-33.0) after sham

  1. Development of a new error field correction coil (C-coil) for DIII-D

    International Nuclear Information System (INIS)

    Robinson, J.I.; Scoville, J.T.

    1995-12-01

    The C-coil recently installed on the DIII-D tokamak was developed to reduce the error fields created by imperfections in the location and geometry of the existing coils used to confine, heat, and shape the plasma. First results from C-coil experiments include stable operation in a 1.6 MA plasma with a density less than 1.0 x 10 13 cm -3 , nearly a factor of three lower density than that achievable without the C-coil. The C-coil has also been used in magnetic braking of the plasma rotation and high energy particle confinement experiments. The C-coil system consists of six individual saddle coils, each 60 degree wide toroidally, spanning the midplane of the vessel with a vertical height of 1.6 m. The coils are located at a major radius of 3.2 m, just outside of the toroidal field coils. The actual shape and geometry of each coil section varied somewhat from the nominal dimensions due to the large number of obstructions to the desired coil path around the already crowded tokamak. Each coil section consists of four turns of 750 MCM insulated copper cable banded with stainless steel straps within the web of a 3 in. x 3 in. stainless steel angle frame. The C-coil structure was designed to resist peak transient radial forces (up to 1,800 Nm) exerted on the coil by the toroidal and ploidal fields. The coil frames were supported from existing poloidal field coil case brackets, coil studs, and various other structures on the tokamak

  2. A Built for Purpose Micro-Hole Coiled Tubing Rig (MCTR)

    Energy Technology Data Exchange (ETDEWEB)

    Bart Patton

    2007-09-30

    This report will serve as the final report on the work performed from the contract period October 2005 thru April 2007. The project 'A Built for Purpose Microhole Coiled Tubing Rig (MCTR)' purpose was to upgrade an existing state-of-the-art Coiled Tubing Drilling Rig to a Microhole Coiled Tubing Rig (MCTR) capable of meeting the specifications and tasks of the Department of Energy. The individual tasks outlined to meet the Department of Energy's specifications are: (1) Concept and development of lubricator and tool deployment system; (2) Concept and development of process control and data acquisition; (3) Concept and development of safety and efficiency improvements; and (4) Final unit integration and testing. The end result of the MCTR upgrade has produced a unit capable of meeting the following requirements: (1) Capable of handling 1-inch through 2-3/8-inch coiled tubing (Currently dressed for 2-3/8-inch coiled tubing and capable of running up to 3-1/2-inch coiled tubing); (2) Capable of drilling and casing surface, intermediate, production and liner hole intervals; (3) Capable of drilling with coiled tubing and has all controls and installation piping for a top drive; (4) Rig is capable of running 7-5/8-inch range 2 casing; and (5) Capable of drilling 5,000 ft true vertical depth (TVD) and 6,000 ft true measured depth (TMD).

  3. Argonne National Laboratory superconducting pulsed coil program

    International Nuclear Information System (INIS)

    Wang, S.T.; Kim, S.H.

    1979-01-01

    The main objectives are to develop high current (approx. 100 kA) cryostable cable configurations with reasonably low ac losses, to build a demonstration pulsed coil, and to develop a rather inexpensive large fiberglass reinforced helium cryostat. A 1.5-MJ cryostable pulsed superconducting coil has been developed and constructed at ANL. The coil has a peak field of 4.5 T at an operating current of 11.0 kA. A large inexpensive plastic cryostat has been developed for testing the pulsed coil. The coil has been pulsed with a maximum dB/dt of 11 T/s. The coil was pulsed more than 4000 cycles. Detailed results of the ac loss measurements and the current sharing of the cryostability will be described

  4. Test facility for PLT TF coils

    International Nuclear Information System (INIS)

    Hearney, J.; File, J.; Dreskin, S.

    1975-01-01

    Past experience with the model C stellerator and other toroidal field devices indicates that mechanical and electrical tests of a toroidal field coil prior to maximum field operation of the device is prudent and desirable. This paper describes a test program for the PLT-TF coils. The test stand consists of one test coil, two background coils and a steel supporting structure. The three coil configuration produces a 67.5 kG field at the inner conductor (38 kG at the bore center) and simulates a 1/R field distribution in the bore of the test coil. The resolution of the field force system and resultant stresses within the test structure are discussed. A test procedure is described which maximizes the information obtained from a 100,000 pulse program

  5. Power loss problems in EXTRAP coil systems

    International Nuclear Information System (INIS)

    Lehnert, B.

    1977-02-01

    The Ohmic power loss in the coils of external ring traps is minimized with respect to the thermonuclear power production. In the case of the DT-reaction this leads to dimensions and power densities being relevant to full-scale reactors. Not only superconducting or refrigerated coil windings can thus be used, but also hot-coil systems which are operated at several hundred degrees centrigrade and form part of a steam cycle and power extraction system. For hot coils the problems of void formation and tritium regeneration have to be further examined. The high beta value leads to moderately large coil stresses. Finally, replacement and repair become simplified by the present coil geometry. (Auth.)

  6. Coil supporting device for thermonuclear device

    International Nuclear Information System (INIS)

    Okubo, Minoru; Ando, Toshiro; Ota, Mitsuru; Ishimura, Masabumi.

    1979-01-01

    Purpose: To lower the bending stress exerted on coils thereby preventing the coils from deformation by branching the outer circumferential support frames of coil support frames disposed at an equal pitch circumferentially to the coils into plurality, and integrally forming them to the inner circumferential support frames. Constitution: Each of the support frames for supporting poloidal coils winding around a vacuum vessel is bisected at the radial midway so that the outer circumferential branches are disposed at an equal pitch and they are formed integrally with the inner circumferential support frames. The inner circumferential support frames are fixed by support posts on a bed and the outer circumferential support frames are mounted to the outer edge of wedge-like support posts. Accordingly, if the coils expand outwardly upon increase in the temperature, the stress exerted on the support frame can be decreased. (Yoshino, Y.)

  7. Split-coil-system SULTAN

    International Nuclear Information System (INIS)

    Vecsey, G.

    1992-08-01

    The high field superconductor test facility SULTAN started operation successfully in May 1992. Originally designed for testing full scale conductors for the large magnets of the next generation fusion reactors, the SULTAN facility installed at PSI (Switzerland) was designed as a common venture of three European Laboratories: ENEA (Italy), ECN (Netherlands) and PSI, and built by ENEA and PSI in the framework of the Euratom Fusion Technology Program. Presently the largest facility in the world, with its superconducting split coil system generating 11 Tesla in a 0.6 m bore, it is ready now for testing superconductor samples with currents up to 50 kA at variable cooling conditions. Similar tests can be arranged also for other applications. SULTAN is offered by the European Community as a contribution to the worldwide cooperation for the next step of fusion reactor development ITER. First measurements on conductor developed by CEA (Cadarache) are now in progress. Others like those of ENEA and CERN will follow. For 1993, a test of an Italian 12 TZ model coil for fusion application is planned. SULTAN is a worldwide unique facility marking the competitive presence of Swiss technology in the field of applied superconductivity research. Based on development and design of PSI, the high field Nb 3 Sn superconductors and coils were fabricated at the works of Kabelwerke Brugg and ABB, numerous Swiss companies contributed to the success of this international effort. Financing of the Swiss contribution of SULTAN was made available by NEFF, BEW, BBW, PSI and EURATOM. (author) figs., tabs., 20 refs

  8. Questions and Advice to the Swedish Radiation Authority in their Current Work on Radiation Safety from Participants in Focus Group Discussions in the Municipalities of Oesthammar and Oskarshamn

    International Nuclear Information System (INIS)

    Drottz-Sjoeberg, Britt-Marie

    2003-01-01

    In connection to their work on developing a 'general advice document', based on the radiation protection law, the Swedish Radiation Authority (SSI) initiated a process in 2002 that welcomed comments and suggestions from the general public, specifically representatives and interested parties involved in the work related to a Swedish repository for high level nuclear wastes. The authority held a seminar in September, and presented the forthcoming task. The present paper summarises and exemplifies discussions in focus groups in October 2002, when participants from the municipalities of Oskarshamn and Oesthammar met to give their input to the authority's ongoing work. The questions and suggestions emerging from the focus groups are classified into three major areas in this presentation: 1. Issues related specifically to radiation and radioactivity. 2. Issues of comprehension of terminology, measurements, risk, and safety. 3. Issues concerning the information process and the transfer of knowledge. The discussion highlights that issues and comments raised by the public are not constrained to specific knowledge questions, e.g. on radiation or risk, but may relate to legal, strategic and political considerations, as well as the basics of the performed analyses and the related assumptions and evaluations. Ideas for improving public knowledge and for facilitating an exchange of information are outlined below

  9. DEVELOPMENT OF COILED TUBING STRESS ANALYSIS

    Directory of Open Access Journals (Sweden)

    Davorin Matanović

    1998-12-01

    Full Text Available The use of coiled tubing is increasing rapidly with drilling of horizontal wells. To satisfy all requirements (larger mechanical stresses, larger fluid capacities the production of larger sizes and better material qualities was developed. Stresses due to axial forces and pressures that coiled tubing is subjected are close to its performance limits. So it is really important to know and understand the behaviour of coiled tubing to avoid its break, burst or collapse in the well.

  10. Performance of Helical Coil Heat Recovery Exchanger using Nanofluid as Coolant

    Directory of Open Access Journals (Sweden)

    Navid Bozorgan

    2015-07-01

    Full Text Available Nanofluids are expected to be a promising coolant condidate in chemical processes for heat transfer system size reduction. This paper focuses on reducing the number of turns in a helical coil heat recovery exchanger with a given heat exchange capacity in a biomass heating plant using γ-Al2O3/n-decane nanofluid as coolant. The nanofluid flows through the tubes and the hot n-hexane flows through the shell. The numerical results show that using nanofluid as coolant in a helical coil heat exchanger can reduce the manufacturing cost of the heat exchanger and pumping power by reducing the number of turns of the coil.

  11. Manufacturing development of the Westinghouse Nb3Sn coil for the Large Coil Test Program

    International Nuclear Information System (INIS)

    Young, J.L.; Vota, T.L.; Singh, S.K.

    1983-01-01

    The Westinghouse Nb 3 Sn Magnet for the Oak Ridge National Laboratory Large Coil Program (LCP) is currently well into the manufacturing phase. This paper identifies the manufacturing processes and development tasks for his unique, advanced coil

  12. Feasibility Study: Ductless Hydronic Distribution Systems with Fan Coil Delivery

    Energy Technology Data Exchange (ETDEWEB)

    Springer, D.; Dakin, B.; Backman, C.

    2012-07-01

    The primary objectives of this study are to estimate potential energy savings relative to conventional ducted air distribution, and to identify equipment requirements, costs, and barriers with a focus on ductless hydronic delivery systems that utilize water-to-air terminal units in each zone. Results indicate that annual heating and cooling energy use can be reduced by up to 27% assuming replacement of the conventional 13 SEER heat pump and coil with a similarly rated air-to-water heat pump.

  13. Optimization of the ECT background coil

    International Nuclear Information System (INIS)

    Ballou, J.K.; Luton, J.N.

    1975-01-01

    This study was begun to optimize the Eccentric Coil Test (ECT) background coil. In the course of this work a general optimization code was obtained, tested, and applied to the ECT problem. So far this code has proven to be very satisfactory. The results obtained with this code and earlier codes have illustrated the parametric behavior of such a coil system and that the optimum for this type system is broad. This study also shows that a background coil with a winding current density of less than 3000 A/cm 2 is not feasible for the ECT models presented in this paper

  14. Magnetic field coil in nuclear fusion device

    International Nuclear Information System (INIS)

    Yamaguchi, Mitsugi; Takano, Hirohisa.

    1975-01-01

    Object: To provide an electrical-insulatively stabilized magnetic field coil in nuclear fusion device, restraining an increase in voltage when plasma current is rapidly changed. Structure: A magnetic field coil comprises coils arranged coaxial with respective vacuum vessels, said coils being wound in positive and reverse polarities so as to form a vertical magnetic field within the plasma. The coils of the positive polarity are arranged along the vacuum vessel inside of an axis vertical in section of the annular plasma and are arranged symmetrically up and down of a horizontal axis. On the other hand, the coils of the reverse polarity are arranged along the vacuum vessel outside of a vertical axis and arranged symmetrically up and down of the horizontal axis. These positive and reverse polarity coils are alternately connected in series, and lead portions of the coils are connected to a power source by means of connecting wires. In this case, lead positions of the coils are arranged in one direction, and the connecting wires are disposed in closely contact relation to offset magnetic fields formed by the connecting wires each other. (Kawakami, Y.)

  15. A precise technique for manufacturing correction coil

    International Nuclear Information System (INIS)

    Schieber, L.

    1992-01-01

    An automated method of manufacturing correction coils has been developed which provides a precise embodiment of the coil design. Numerically controlled machines have been developed to accurately position coil windings on the beam tube. Two types of machines have been built. One machine bonds the wire to a substrate which is wrapped around the beam tube after it is completed while the second machine bonds the wire directly to the beam tube. Both machines use the Multiwire reg-sign technique of bonding the wire to the substrate utilizing an ultrasonic stylus. These machines are being used to manufacture coils for both the SSC and RHIC

  16. Tesla coil theoretical model and experimental verification

    OpenAIRE

    Voitkans, Janis; Voitkans, Arnis

    2014-01-01

    Abstract – In this paper a theoretical model of a Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wired format, where the line voltage is measured against electrically neutral space. It is shown that equivalent two-wired scheme can be found for a single-wired scheme and already known long line theory can be applied to a Tesla coil. Formulas for calculation of voltage in a Tesla coil by coordinate and calculation of resonance fre...

  17. The energizing of a NMR superconducting coil by a superconducting rectifier

    International Nuclear Information System (INIS)

    Sikkenga, J.; ten Kate, H.H.J.; van der Klundert, L.J.M.; Knoben, J.; Kraaij, G.J.; Spuorenberg, C.J.G.

    1985-01-01

    NMR magnets require a good homogeneity within a certain volume and an excellent field stability. The homogeneity can be met using a superconducting shim coil system. The field stability requires a constant current, although in many cases the current decay time constant is too low, due to imperfections in the superconducting wire and joints. This can be overcome using a rectifier. The rectifier can also be used to load the coil. The combination and interaction of the superconducting NMR coil (2.0 Tesla and 0.35 m cold bore) and the rectifier (20 W / 1 kA) is tested. The safety of the system is discussed. The shim coil system can compensate the strayfield of the rectifier. The field decay compensation will be discussed

  18. Superconducting Coil of Po Dipole

    CERN Multimedia

    1983-01-01

    The Po superconducting dipole was built as a prototype beam transport magnet for the SPS extracted proton beam P0. Its main features were: coil aperture 72 mm, length 5 m, room-temperature yoke, NbTi cable conductor impregnated with solder, nominal field 4.2 T at 4.7 K (87% of critical field). It reached its nominal field without any quench.After this successful test up to its nominal field of 4.2 T, the power was not raised to reach a quench. The magnet was not installed in a beam and had no other further use. Nevertheless its construction provided knowledges and experience which became useful in the design and construction of the LHC magnets. The photo shows a detail of the inner layer winding before superposing the outer layer to form the complete coil of a pole. Worth noticing is the interleaved glass-epoxy sheet (white) with grooved channels for the flow of cooling helium. See also 8211532X.

  19. The feasibility and safety of high-intensity focused ultrasound combined with low-dose external beam radiotherapy as supplemental therapy for advanced prostate cancer following hormonal therapy.

    Science.gov (United States)

    Wu, Rui-Yi; Wang, Guo-Min; Xu, Lei; Zhang, Bo-Heng; Xu, Ye-Qing; Zeng, Zhao-Chong; Chen, Bing

    2011-05-01

    The aim of this study was to investigate the feasibility and safety of high-intensity focused ultrasound (HIFU) combined with (+) low-dose external beam radiotherapy (LRT) as supplemental therapy for advanced prostate cancer (PCa) following hormonal therapy (HT). Our definition of HIFU+LRT refers to treating primary tumour lesions with HIFU in place of reduced field boost irradiation to the prostate, while retaining four-field box irradiation to the pelvis in conventional-dose external beam radiotherapy (CRT). We performed a prospective, controlled and non-randomized study on 120 patients with advanced PCa after HT who received HIFU, CRT, HIFU+LRT and HT alone, respectively. CT/MR imaging showed the primary tumours and pelvic lymph node metastases visibly shrank or even disappeared after HIFU+LRT treatment. There were significant differences among four groups with regard to overall survival (OS) and disease-specific survival (DSS) curves (P = 0.018 and 0.015). Further comparison between each pair of groups suggested that the long-term DSS of the HIFU+LRT group was higher than those of the other three groups, but there was no significant difference between the HIFU+LRT group and the CRT group. Multivariable Cox's proportional hazard model showed that both HIFU+LRT and CRT were independently associated with DSS (P = 0.001 and 0.035) and had protective effects with regard to the risk of death. Compared with CRT, HIFU+LRT significantly decreased incidences of radiation-related late gastrointestinal (GI) and genitourinary (GU) toxicity grade ≥ II. In conclusion, long-term survival of patients with advanced PCa benefited from strengthening local control of primary tumour and regional lymph node metastases after HT. As an alternative to CRT, HIFU+LRT showed good efficacy and better safety.

  20. Efficacy and safety of ultrasound-guided high intensity focused ultrasound ablation of symptomatic uterine fibroids in Black women: a preliminary study.

    Science.gov (United States)

    Zhang, C; Jacobson, H; Ngobese, Z E; Setzen, R

    2017-08-01

    To evaluate the therapeutic effect and safety of ultrasound-guided high-intensity focused ultrasound (USgHIFU) treatment on symptomatic uterine fibroids in Black women. A feasibility study. Gynaecological department in a teaching hospital in South Africa. Premenopausal women with uterus fibroids. Twenty-six patients with 53 fibroids who underwent USgHIFU treatment were enrolled. The USgHIFU treatment information was recorded, including treatment time, sonication time and total energy. Adverse events were also observed and recorded during and after treatment. Safety and efficacy of USgHIFU for the treatment of uterine fibroids in Black women. The median volume of fibroids was 52.7 (interquartile range, 18.6-177.4) cm 3 . According to USgHIFU treatment plan, total energy of 298.6 ± 169.3 kJ (range, 76.0-889.2) within treatment time of 90.3 ± 43.3 minutes (range, 14.0-208.0), in which sonication time of 774.0 ± 432.9 seconds (range, 190.0-2224.0) was used to ablate fibroids. The average ablation rate was 80.6 ± 9.7% (range, 46.5-94.5%). During the procedure, 69.2% of the patients reported lower abdominal pain, 57.7% sciatic/buttock pain, 38.5% burning skin, and 34.6% transient leg pain. No severe complications were observed. USgHIFU is feasible and safe to use to treat symptomatic uterine fibroids in Black women. Multiple uterine fibroids are more frequently detected in Black women. USgHIFU is feasible and safe for the treatment of uterine fibroids in Black women. © 2017 Royal College of Obstetricians and Gynaecologists.

  1. Long-Term Safety of Repeated Blood-Brain Barrier Opening via Focused Ultrasound with Microbubbles in Non-Human Primates Performing a Cognitive Task.

    Science.gov (United States)

    Downs, Matthew E; Buch, Amanda; Sierra, Carlos; Karakatsani, Maria Eleni; Teichert, Tobias; Chen, Shangshang; Konofagou, Elisa E; Ferrera, Vincent P

    2015-01-01

    Focused Ultrasound (FUS) coupled with intravenous administration of microbubbles (MB) is a non-invasive technique that has been shown to reliably open (increase the permeability of) the blood-brain barrier (BBB) in multiple in vivo models including non-human primates (NHP). This procedure has shown promise for clinical and basic science applications, yet the safety and potential neurological effects of long term application in NHP requires further investigation under parameters shown to be efficacious in that species (500 kHz, 200-400 kPa, 4-5 μm MB, 2 minute sonication). In this study, we repeatedly opened the BBB in the caudate and putamen regions of the basal ganglia of 4 NHP using FUS with systemically-administered MB over 4-20 months. We assessed the safety of the FUS with MB procedure using MRI to detect edema or hemorrhaging in the brain. Contrast enhanced T1-weighted MRI sequences showed a 98% success rate for openings in the targeted regions. T2-weighted and SWI sequences indicated a lack edema in the majority of the cases. We investigated potential neurological effects of the FUS with MB procedure through quantitative cognitive testing of' visual, cognitive, motivational, and motor function using a random dot motion task with reward magnitude bias presented on a touchpanel display. Reaction times during the task significantly increased on the day of the FUS with MB procedure. This increase returned to baseline within 4-5 days after the procedure. Visual motion discrimination thresholds were unaffected. Our results indicate FUS with MB can be a safe method for repeated opening of the BBB at the basal ganglia in NHP for up to 20 months without any long-term negative physiological or neurological effects with the parameters used.

  2. Fall risk awareness and safety precautions taken by older community-dwelling women and men--a qualitative study using focus group discussions.

    Directory of Open Access Journals (Sweden)

    Petra Pohl

    Full Text Available Daily life requires frequent estimations of the risk of falling and the ability to avoid a fall. The objective of this study was to explore older women's and men's understanding of fall risk and their experiences with safety precautions taken to prevent falls.A qualitative study with focus group discussions was conducted. Eighteen community-dwelling people [10 women and 8 men] with and without a history of falls were purposively recruited. Participants were divided into two groups, and each group met four times. A participatory and appreciative action and reflection approach was used to guide the discussions. All discussions were audio recorded and transcribed verbatim. Data were analysed by qualitative content analysis, and categories were determined inductively.Three categories describing the process of becoming aware of fall risks in everyday life were identified: 1] Facing various feelings, 2] Recognizing one's fall risk, and 3] Taking precautions. Each category comprised several subcategories. The comprehensive theme derived from the categories was "Safety precautions through fall risk awareness". Three strategies of ignoring [continuing a risky activity], gaining insight [realizing the danger in a certain situation], and anticipating [thinking ahead and acting in advance] were related to all choices of actions and could fluctuate in the same person in different contexts.The fall risk awareness process might be initiated for various reasons and can involve different feelings and precautions as well as different strategies. This finding highlights that there are many possible channels to reach older people with information about fall risk and fall prevention, including the media and their peers. The findings offer a deeper understanding of older peoples' conceptualizations about fall risk awareness and make an important contribution to the development and implementation of fall prevention programmes.

  3. Multicoil2: predicting coiled coils and their oligomerization states from sequence in the twilight zone.

    Directory of Open Access Journals (Sweden)

    Jason Trigg

    Full Text Available The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices of coiled coils in protein sequences. Multicoil2 combines the pairwise correlations of the previous Multicoil method with the flexibility of Hidden Markov Models (HMMs in a Markov Random Field (MRF. The resulting algorithm integrates sequence features, including pairwise interactions, through multinomial logistic regression to devise an optimized scoring function for distinguishing dimer, trimer and non-coiled-coil oligomerization states; this scoring function is used to produce Markov Random Field potentials that incorporate pairwise correlations localized in sequence. Multicoil2 significantly improves both coiled-coil detection and dimer versus trimer state prediction over the original Multicoil algorithm retrained on a newly-constructed database of coiled-coil sequences. The new database, comprised of 2,105 sequences containing 124,088 residues, includes reliable structural annotations based on experimental data in the literature. Notably, the enhanced performance of Multicoil2 is evident when tested in stringent leave-family-out cross-validation on the new database, reflecting expected performance on challenging new prediction targets that have minimal sequence similarity to known coiled-coil families. The Multicoil2 program and training database are available for download from http://multicoil2.csail.mit.edu.

  4. Design of the coolant system for the Large Coil Test Facility pulse coils

    International Nuclear Information System (INIS)

    Bridgman, C.; Ryan, T.L.

    1983-01-01

    The pulse coils will be a part of the Large Coil Test Facility in Oak Ridge, Tennessee, which is designed to test six large tokamak-type superconducting coils. The pulse coil set consists of two resistive coaxial solenoid coils, mounted so that their magnetic axis is perpendicular to the toroidal field lines of the test coil. The pulse coils provide transient vertical fields at test coil locations to simulate the pulsed vertical fields present in tokamak devices. The pulse coils are designed to be pulsed for 30 s every 150 s, which results in a Joule heating of 116 kW per coil. In order to provide this capability, the pulse coil coolant system is required to deliver 6.3 L/s (100 gpm) of subcooled liquid nitrogen at 10-atm absolute pressure. The coolant system can also cool down each pulse coil from room temperature to liquid nitrogen temperature. This paper provides details of the pumping and heat exchange equipment designed for the coolant system and of the associated instrumentation and controls

  5. Measurement of heating coil temperature for e-cigarettes with a "top-coil" clearomizer.

    Science.gov (United States)

    Chen, Wenhao; Wang, Ping; Ito, Kazuhide; Fowles, Jeff; Shusterman, Dennis; Jaques, Peter A; Kumagai, Kazukiyo

    2018-01-01

    To determine the effect of applied power settings, coil wetness conditions, and e-liquid compositions on the coil heating temperature for e-cigarettes with a "top-coil" clearomizer, and to make associations of coil conditions with emission of toxic carbonyl compounds by combining results herein with the literature. The coil temperature of a second generation e-cigarette was measured at various applied power levels, coil conditions, and e-liquid compositions, including (1) measurements by thermocouple at three e-liquid fill levels (dry, wet-through-wick, and full-wet), three coil resistances (low, standard, and high), and four voltage settings (3-6 V) for multiple coils using propylene glycol (PG) as a test liquid; (2) measurements by thermocouple at additional degrees of coil wetness for a high resistance coil using PG; and (3) measurements by both thermocouple and infrared (IR) camera for high resistance coils using PG alone and a 1:1 (wt/wt) mixture of PG and glycerol (PG/GL). For single point thermocouple measurements with PG, coil temperatures ranged from 322 ‒ 1008°C, 145 ‒ 334°C, and 110 ‒ 185°C under dry, wet-through-wick, and full-wet conditions, respectively, for the total of 13 replaceable coil heads. For conditions measured with both a thermocouple and an IR camera, all thermocouple measurements were between the minimum and maximum across-coil IR camera measurements and equal to 74% ‒ 115% of the across-coil mean, depending on test conditions. The IR camera showed details of the non-uniform temperature distribution across heating coils. The large temperature variations under wet-through-wick conditions may explain the large variations in formaldehyde formation rate reported in the literature for such "top-coil" clearomizers. This study established a simple and straight-forward protocol to systematically measure e-cigarette coil heating temperature under dry, wet-through-wick, and full-wet conditions. In addition to applied power, the

  6. Progress on large superconducting toroidal field coils

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Luton, J.N.; Thompson, P.B.; Beard, D.S.

    1979-01-01

    Large superconducting toroidal field coils of competing designs are being produced by six major industrial teams. In the US, teams headed by General Dynamics Convair, General Electric, and Westinghouse are under contract to design and fabricate one coil each to specifications established by the Large Coil Program. A facility for testing 6 coils in a toroidal array at fields to 8 to 12 tesla is under construction at Oak Ridge. Through an international agreement, EURATOM, Japan, and Switzerland will produce one coil each for testing with the US coils. Each test coil will have a 2.5 x 3.5 m D-shape winding bore and is designed to operate at a current of 10 to 18 kA at a peak field of 8T while subjected to pulsed fields of 0.14 T applied in 1.0 s. There are significant differences among the six coil designs: five use NbTi, one Nb 3 Sn; three are cooled by pool boiling helium, three by forced flow; five have welded or bolted stainless steel coil cases, one has aluminum plate structure. All are designed to be cryostable at 8T, with structural margin for extended operation. The three US coil teams are almost or completely finished with detailed design and are now procuring materials and setting up manufacturing equipment. The non-US teams are at various stages of verification testing and design. The GDC and GE coils are scheduled for delivery in the spring of 1981 and the others will be completed a year later. The 11-m diameter vessel at the test facility has been completed and major components of the test stand are being procured. Engineering and procurement to upgrade the helium liquifier-refrigerator system are under way

  7. Dynamics and rheology of finitely extensible polymer coils: An overview

    Science.gov (United States)

    Yao, Donggang

    2017-05-01

    One contemporary research issue in non-Newtonian fluid mechanics is to accurately and effectively model viscoelastic polymer flow of practical relevance. In the past several years, we have been working on the formulation of a finitely extensible coil model for polymer flow, particularly including these elements: (1) decoupled equations for kinematical and dynamical variables, (2) logarithmic relaxation at large deformation, (3) rotational retardation, (4) controllable straining, and (5) finite stretch. In this paper, we provide a constructive overview of this nonlinear coil formulation focusing on integration of these elements in a single, unified constitutive model with a minimal number of model parameters that are linked with corresponding physical processes. We also use this opportunity to share the rationale and thought process in the model development. In one particular implement of the general formulation, three parameters are used to tackle with the principal dynamics of a deforming polymer coil: one for finite stretch dictated by a ceiling stretch of the coil, the second one for rotational recovery/retardation, and the third one for adjusting stretch hardening of the rubbery coil. The new model, even in a single mode, is able to simultaneously predict practical material functions in simple shear and coaxial extension and to fit well to representative experimental data. Particularly in the steady-state (or quasi-steady state) flow case, a nearly closed-form stress to velocity gradient relationship can be derived with which shear thinning and elongational thickening can be simultaneously considered while computational advantages of a classical GNF model is retained. The model also fits reasonably well to representative experimental transient data for both shear and extension.

  8. Abciximab for thrombolysis during intracranial aneurysm coiling

    International Nuclear Information System (INIS)

    Gralla, Jan; Rennie, Adam T.M.; Corkill, Rufus A.; Lalloo, Shivendra T.; Molyneux, Andrew; Byrne, James V.; Kuker, Wilhem

    2008-01-01

    Thrombotic events are a common and severe complication of endovascular aneurysm treatment with significant impact on patients' outcome. This study evaluates risk factors for thrombus formation and assesses the efficacy and safety of abciximab for clot dissolution. All patients treated with abciximab during (41 patients) or shortly after (22 patients) intracranial aneurysm coil embolisation were retrieved from the institutional database (2000 to 2007, 1,250 patients). Sixty-three patients (mean age, 55.3 years, ±12.8) had received either intra-arterial or intravenous abciximab. Risk factors for clot formation were assessed and the angiographic and clinical outcome evaluated. No aneurysm rupture occurred during or after abciximab application. The intra-procedural rate of total recanalisation was 68.3%. Thromboembolic complications were frequently found in aneurysms of the Acom complex and of the basilar artery, whilst internal carotid artery aneurysms were underrepresented. Two patients died of treatment-related intracranial haemorrhages into preexisting cerebral infarcts. Two patients developed a symptomatic groin haematoma. Abciximab is efficacious and safe for thrombolysis during and after endovascular intracranial aneurysm treatment in the absence of preexisting ischaemic stroke. (orig.)

  9. Outcomes with single-coil versus dual-coil implantable cardioverter defibrillators: a meta-analysis.

    Science.gov (United States)

    Sunderland, Nicholas; Kaura, Amit; Murgatroyd, Francis; Dhillon, Para; Scott, Paul A

    2018-03-01

    Dual-coil implantable cardioverter defibrillator (ICD) leads have traditionally been used over single-coil leads due to concerns regarding high defibrillation thresholds (DFT) and consequent poor shock efficacy. However, accumulating evidence suggests that this position may be unfounded and that dual-coil leads may also be associated with higher complication rates during lead extraction. This meta-analysis collates data comparing dual- and single-coil ICD leads. Electronic databases were systematically searched for randomized controlled trials (RCT) and non-randomized studies comparing single-coil and dual-coil leads. The mean differences in DFT and summary estimates of the odds-ratio (OR) for first-shock efficacy and the hazard-ratio (HR) for all-cause mortality were calculated using random effects models. Eighteen studies including a total of 138,124 patients were identified. Dual-coil leads were associated with a lower DFT compared to single coil leads (mean difference -0.83J; 95% confidence interval [CI] -1.39--0.27; P = 0.004). There was no difference in the first-shock success rate with dual-coil compared to single-coil leads (OR 0.74; 95%CI 0.45-1.21; P=0.22). There was a significantly lower risk of all-cause mortality associated with single-coil leads (HR 0.91; 95%CI 0.86-0.95; P dual-coil leads. The mortality benefit with single-coil leads most likely represents patient selection bias. Given the increased risk and complexity of extracting dual-coil leads, centres should strongly consider single-coil ICD leads as the lead of choice for routine new left-sided ICD implants. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions, please email: journals.permissions@oup.com.

  10. Constructing a Model for Safe Nuclear Energy. General Conference Event to Focus on Innovative Cross-cutting Approach to Nuclear Safety

    International Nuclear Information System (INIS)

    Verlini, Giovanni

    2011-01-01

    Two innovative IAEA Extra-Budgetary Programmes, supporting safe nuclear energy in Bulgaria and Romania, passed their one-year milestone in 2010. Funded by the Norwegian government, these programmes are unique in that they cover separate but cross-cutting issues related to nuclear safety, including safety culture, safety assessments, risk management and resource management.

  11. Toroidal field coils for the PDX machine

    International Nuclear Information System (INIS)

    Bushnell, C.W.

    1975-01-01

    This paper describes the engineering design features of the TF coils for the PDX machine. Included are design details of the electrical insulation, water cooling, and coil segment joint which allows access to the central machine area. A discussion of the problems anticipated in the manufacture and the planned solutions are presented

  12. Operator coil monitoring Acceptance Test Procedure

    International Nuclear Information System (INIS)

    Erhart, M.F.

    1995-01-01

    The readiness of the Data Acquisition and Control System (DACS) to provide monitoring and control of the Programmable Logic Controller (PLC) abort coils from the Master and RSS stations will be systematically tested during performance of this procedure. It should be noted that these are not physical abort coils but software coils controlled by the software's ladder logic. The readiness of the DACS to properly interface with the ENRAF wire level gauge installed in the SY-101 storage tank will also be tested. During this test, a verification of all abort coil indications will be conducted at the DACS Development Facility in the 306E Building by injecting an input signal for each DACS sensor that has an associated abort coil until the abort coil actuates, and then ensuring that the status of the abort coil indicated at the Master and RSS stations is correct. Each abort coil will also be tested to ensure that the ''ENABLE'' and ''DISABLE'' controls from the Master and RSS stations function correctly, and only with the use of proper passwords

  13. Coil Optimization for High Temperature Superconductor Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    2011-01-01

    This paper presents topology optimization of HTS racetrack coils for large HTS synchronous machines. The topology optimization is used to acquire optimal coil designs for the excitation system of 3 T HTS machines. Several tapes are evaluated and the optimization results are discussed. The optimiz...

  14. The bar coil for NMR tomograph

    International Nuclear Information System (INIS)

    Bogorodzki, P.; Piatkowski, A.; Wasielewski, J.

    1995-01-01

    The bar coil (bi-planar) for the NMR tomograph, designed for medical diagnostics, has been described. The tests of coil shown that it generates good homogenous magnetic field in a big volume what results in improving of the signal-to-noise ratio

  15. Evidence-based pathology: umbilical cord coiling.

    Science.gov (United States)

    Khong, T Y

    2010-12-01

    The generation of a pathology test result must be based on criteria that are proven to be acceptably reproducible and clinically relevant to be evidence-based. This review de-constructs the umbilical cord coiling index to illustrate how it can stray from being evidence-based. Publications related to umbilical cord coiling were retrieved and analysed with regard to how the umbilical coiling index was calculated, abnormal coiling was defined and reference ranges were constructed. Errors and other influences that can occur with the measurement of the length of the umbilical cord or of the number of coils can compromise the generation of the coiling index. Definitions of abnormal coiling are not consistent in the literature. Reference ranges defining hypocoiling or hypercoiling have not taken those potential errors or the possible effect of gestational age into account. Even the way numerical test results in anatomical pathology are generated, as illustrated by the umbilical coiling index, warrants a critical analysis into its evidence base to ensure that they are reproducible or free from errors.

  16. Composite coils for toroidal field coils and method of using same

    International Nuclear Information System (INIS)

    Perkins, R. G.; Trujillo, S. M.

    1985-01-01

    A composite toroidal field (TF) generating means consisting of segmented magnetic coil windings is disclosed. Each coil winding of the TF generating means consists of a copper or copper alloy conductor segment and an aluminum or aluminum alloy conductor segment. The conductor segments are joined at a high strength, low electrical resistance joint and the joint may either be a mechanical or metallurgical one. The use of the aluminum or aluminum alloy conductor segments improves the neutron economy of the reactor with which the TF coil is associated and reduces TF coil nuclear heating and heating gradients, and activation in the TF coils

  17. Analysis of mechanical characteristics of superconducting field coil for 17 MW class high temperature superconducting synchronous motor

    International Nuclear Information System (INIS)

    Kim, J. H.; Park, S. I.; Im, S. H.; Kim, H. M.

    2013-01-01

    Superconducting field coils using a high-temperature superconducting (HTS) wires with high current density generate high magnetic field of 2 to 5 [T] and electromagnetic force (Lorentz force) acting on the superconducting field coils also become a very strong from the point of view of a mechanical characteristics. Because mechanical stress caused by these powerful electromagnetic force is one of the factors which worsens the critical current performance and structural characteristics of HTS wire, the mechanical stress analysis should be performed when designing the superconducting field coils. In this paper, as part of structural design of superconducting field coils for 17 MW class superconducting ship propulsion motor, mechanical stress acting on the superconducting field coils was analyzed and structural safety was also determined by the coupling analysis system that is consists of commercial electromagnetic field analysis program and structural analysis program.

  18. Short time efficacy and safety of focused monopolar radiofrequency device for labial laxity improvement-noninvasive labia tissue tightening. A prospective cohort study.

    Science.gov (United States)

    Fistonić, Ivan; Sorta Bilajac Turina, Iva; Fistonić, Nikola; Marton, Ingrid

    2016-03-01

    To evaluate safety and efficacy of focused monopolar radio frequency (RF) device for non-invasive labia tissue tightening and improvement of labial laxity. This prospective cohort study participants were 17 female subjects aged between 27 and 56 years with lax skin at the labia area. All subjects received four consecutive treatments at 7-day intervals with RF device (Exilis Protege IntimaR, BTL Industries Inc., Boston, MA). The primary efficacy outcome measure was defined as one or more point improvement on 1-4 scale for vulva appearance determined by three blinded evaluators. Digital photographs were taken at the baseline and 1 month after the last treatment. Sexual gratification was assessed with Female Sexual Functioning Index (FSFI) and patient discomfort by Visual Analogue Scale (VAS). An average 2.9 (of maximum 4) points improvement rate in vulvar appearance was observed (P RF device for non-invasive labia tissue tightening. The treatment is effective and safe with high patient satisfaction. © 2016 Wiley Periodicals, Inc.

  19. Status of the cold test facility for the JT-60SA tokamak toroidal field coils

    Energy Technology Data Exchange (ETDEWEB)

    Abdel Maksoud, Walid, E-mail: walid.abdelmaksoud@cea.fr; Bargueden, Patrick; Bouty, André; Dispau, Gilles; Donati, André; Eppelle, Dominique; Genini, Laurent; Guiho, Patrice; Guihard, Quentin; Joubert, Jean-Michel; Kuster, Olivier; Médioni, Damien; Molinié, Frédéric; Sinanna, Armand; Solenne, Nicolas; Somson, Sébastien; Vieillard, Laurence

    2015-10-15

    Highlights: • The 5 K cryogenic loop includes a 500 W refrigerator and a She cold pump. • The coils are energized thanks to a 25.7 kA power supply and HTS current leads. • Temperature margin tests between 5 K and 7.5 K will be made on each coil. • A magnet safety system protects each double pancake of the coil in case of quench. • Instrumentation is monitored on a 1 Hz to 10 kHz fast acquisition system. - Abstract: JT-60SA is a fusion experiment which is jointly constructed by Japan and Europe and which shall contribute to the early realization of fusion energy, by providing support to the operation of ITER, and by addressing key physics issues for ITER and DEMO. In order to achieve these goals, the existing JT-60U experiment will be upgraded to JT-60SA by using superconducting coils. The 18 TF coils of the JT-60SA device will be provided by European industry and tested in a Cold Test Facility (CTF) at CEA Saclay. The coils will be tested at the nominal current of 25.7 kA and will be cooled with supercritical helium between 5 K and 7.5 K to check the temperature margin against a quench. The main objective of these tests is to check the TF coils performance and hence mitigate the fabrication risks. The most important components of the facility are: a 11.5 m × 6.5 m large cryostat in which the TF coils will be thermally insulated by vacuum; a 500 W helium refrigerator and a valve box to cool the coils down to 5 K and circulate 24 g/s of supercritical helium through the winding pack and through the casing; a power supply and HTS current leads to energize the coil; the control and instrumentation equipment (sensors, PLC's, supervision system, fast data acquisition system, etc.) and the Magnet Safety System (MSS) that protects the coils in case of quench. The paper will give an overview of the design of this large facility and the status of its realization.

  20. Startup of Large Coil Test Facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1984-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Eventually, six different coils from four countries will be tested. Operations began in 1983 with acceptance testing of the helium refrigerator/liquefier system. Comprehensive shakedown of the facility and tests with the first three coils (from Japan, the United States, and Switzerland) were successfully accomplished in the summer of 1984. Currents up to 10,200 A and fields up to 6.4 T were reached. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils

  1. Startup of Large Coil Test Facility

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Bohanan, R.E.; Fietz, W.A.; Luton, J.N.; May, J.R.

    1985-01-01

    The Large Coil Test Facility (LCTF) is being used to test superconducting toroidal field coils about one-third the size of those for INTOR. Eventually, six different coils from four countries will be tested. Operations began in 1983 with acceptance testing of the helium refrigerator/liquefier system. Comprehensive shakedown of the facility and tests with the first three coils (from Japan, the United States, and Switzerland) were successfully accomplished in the summer of 1984. Currents up to 10,200 A and fields up to 6.4 T were reached. Data were obtained on performance of refrigerator, helium distribution, power supplies, controls, and data acquisition systems and on the acoustic emission, voltages, currents, and mechanical strains during charging and discharging the coils

  2. Helically coiled tube heat exchanger

    International Nuclear Information System (INIS)

    Harris, A.M.

    1981-01-01

    In a heat exchanger such as a steam generator for a nuclear reactor, two or more bundles of helically coiled tubes are arranged in series with the tubes in each bundle integrally continuing through the tube bundles arranged in series therewith. Pitch values for the tubing in any pair of tube bundles, taken transverse to the path of the reactor coolant flow about the tubes, are selected as a ratio of two unequal integers to permit efficient operation of each tube bundle while maintaining the various tube bundles of the heat exchanger within a compact envelope. Preferably, the helix angle and tube pitch parallel to the path of coolant flow are constant for all tubes in a single bundle so that the tubes are of approximately the same length within each bundle

  3. Effects of passive coils on spheromak gross MHD instabilities

    International Nuclear Information System (INIS)

    Munson, C.; Janos, A.; Paul, S.; Wysocki, F.; Yamada, M.

    1983-01-01

    The experimental investigation of the effectiveness of figure-8 coils in stabilizing the n=1 tilting mode of spheromak plasmas in Proto S-1 A/B is extended. In addition, another coil configuration, the saddle coil, is examined

  4. A six-channel pediatric coil array for detection of children spinal pathologies by MRI at 1.5 Tesla

    Science.gov (United States)

    López Terrones, Marcos Alonso; Solís-Nájera, Sergio Enrique

    2014-11-01

    Nowadays, magnetic resonance (MR) in Mexico has become a standard technique for clinical imaging. Although most of the times the MR systems contain only coils oriented for adults. Radiologists use these coils for children studies due to the non-availability of pediatric coils. Image quality is decreased due to the low signal to noise ratio delivered to the system. The development of RF coils is always focused towards increasing SNR and optimizing the RF penetration into the sample. Moreover, spinal pathologies in children, which are an important topic in pediatric care, cover congenital and neuromuscular disorders that occur in childhood. In this work, the design of a dedicated six-channel coil for detection of spinal pathologies at 1.5 Tesla is addressed. Numerical electromagnetic simulations were performed in order to evaluate their magnetic field performance at (63.6 MHz) 1.5 Tesla. The magnetic field uniformity as well as the RF penetration depth of the coil configurations was evaluated in order to find the best/optimized coil array configuration. The coil is comprised of three rows, one with 4 coil elements and two with only one coil element. Phantom and in vivo images were acquired with the six-channel pediatric coil array. The phantom images agree with the simulated data. In vivo images acquired with the 6-channel pediatric coil array have shown very good penetration depth and homogeneity, which allow better image quality throughout the whole FOV. In addition, the parallel imaging capabilities of the array allow the acceleration of the experiments avoiding possible motion artifacts.

  5. A six-channel pediatric coil array for detection of children spinal pathologies by MRI at 1.5 Tesla

    Energy Technology Data Exchange (ETDEWEB)

    López Terrones, Marcos Alonso, E-mail: malt.marcos@gmail.com [Ingeniería Biomédica, Dirección de Planeación, Servicios de Salud de Durango. Cuauhtémoc 225 Norte, Durango, Durango 34000 (Mexico); Solís-Nájera, Sergio Enrique, E-mail: solisnajera@ciencias.unam.mx [Facultad de Ciencias, Universidad Nacional Autónoma de México, México, DF 04510 (Mexico)

    2014-11-07

    Nowadays, magnetic resonance (MR) in Mexico has become a standard technique for clinical imaging. Although most of the times the MR systems contain only coils oriented for adults. Radiologists use these coils for children studies due to the non-availability of pediatric coils. Image quality is decreased due to the low signal to noise ratio delivered to the system. The development of RF coils is always focused towards increasing SNR and optimizing the RF penetration into the sample. Moreover, spinal pathologies in children, which are an important topic in pediatric care, cover congenital and neuromuscular disorders that occur in childhood. In this work, the design of a dedicated six-channel coil for detection of spinal pathologies at 1.5 Tesla is addressed. Numerical electromagnetic simulations were performed in order to evaluate their magnetic field performance at (63.6 MHz) 1.5 Tesla. The magnetic field uniformity as well as the RF penetration depth of the coil configurations was evaluated in order to find the best/optimized coil array configuration. The coil is comprised of three rows, one with 4 coil elements and two with only one coil element. Phantom and in vivo images were acquired with the six-channel pediatric coil array. The phantom images agree with the simulated data. In vivo images acquired with the 6-channel pediatric coil array have shown very good penetration depth and homogeneity, which allow better image quality throughout the whole FOV. In addition, the parallel imaging capabilities of the array allow the acceleration of the experiments avoiding possible motion artifacts.

  6. Focus on focusing

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    The discovery and impact of the principle of strong focusing was celebrated at a history Symposium at Stanford on 25 July in the course of the 1985 US Summer School on Particle Accelerators. Burt Richter, Stanford Linac Director, who introduced all the speakers with well chosen reminders about their various contributions related to the theme of the symposium, remarked that it was an appropriate time to be lauding the great contributions of accelerator physicists following the Nobel Prize award to Simon van der Meer for outstanding achievements in accelerator physics

  7. Focus on focusing

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1985-10-15

    The discovery and impact of the principle of strong focusing was celebrated at a history Symposium at Stanford on 25 July in the course of the 1985 US Summer School on Particle Accelerators. Burt Richter, Stanford Linac Director, who introduced all the speakers with well chosen reminders about their various contributions related to the theme of the symposium, remarked that it was an appropriate time to be lauding the great contributions of accelerator physicists following the Nobel Prize award to Simon van der Meer for outstanding achievements in accelerator physics.

  8. Clinical Application of Insertion Force Sensor System for Coil Embolization of Intracranial Aneurysms.

    Science.gov (United States)

    Matsubara, Noriaki; Miyachi, Shigeru; Izumi, Takashi; Yamada, Hiroyuki; Marui, Naoki; Ota, Keisuke; Tajima, Hayato; Shintai, Kazunori; Ito, Masashi; Imai, Tasuku; Nishihori, Masahiro; Wakabayashi, Toshihiko

    2017-09-01

    In endovascular embolization for intracranial aneurysms, it is important to properly control the coil insertion force. However, the force can only be subjectively detected by the subtle feedback experienced by neurointerventionists at their fingertips. The authors envisioned a system that would objectively sense and quantify that force. In this article, coil insertion force was measured in cases of intracranial aneurysm using this sensor, and its actual clinical application was investigated. The sensor consists of a hemostatic valve (Y-connector). A little flexure was intentionally added in the device, and it creates a bend in the delivery wire. The sensor measures the change in the position of the bent wire depending on the insertion force and translates it into a force value. Using this, embolization was performed for 10 unruptured intracranial aneurysms. The sensor adequately recorded the force, and it reflected the operators' usual clinical experience. The presence of the sensor did not affect the procedures. The sensor enabled the operators to objectively note and evaluate the insertion force and better cooperative handling was possible. Additionally, other members of the intervention team shared the information. Force records demonstrated the characteristic patterns according to every stage of coiling (framing, filling, and finishing). The force sensor system adequately measured coil insertion force in intracranial aneurysm coil embolization procedures. The safety of this sensor was demonstrated in clinical application for the limited number of patients. This system is useful adjunct for assisting during coil embolization for an intracranial aneurysm. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Middle and long-term follow-up of intracranial aneurysms treated with Matrix detachable coils

    International Nuclear Information System (INIS)

    Wu Xi; Liu Jianmin; Huang Qinghai; Xu Yi

    2008-01-01

    Objective: This study was undertaken to evaluate the safety of the polyglycolic/polylactic acid (PGLA)-coated Matrix detachable coils (Matrix) and analyze factors which may relate to the recanalization rate of the Matrix coils in the treatment of intracranial aneurysms. Methods: 75 patients underwent 79 aneurysm treatments with Matrix coils from May 2003 to July 2005 were retrospectively investigated. Morphological changes were compared postoperatively with last-follow-up digital subtraction angiography (DSA) by using the Raymond scale. We defined incomplete recanalization or stable aneurysms as uncured, while those of progressive occlusion or complete occlusion aneurysms demonstrated on the last-follow-up imagings as cured. We also utilized Cox model for analyzing the relationships between factors including age, gender, degree of aneurysmal occlusion, stenting, aneurysm neck size, aneurysm maximum size and Matrix coils length (%) and the long-term angiographic follow-up results. Results: The correlative surgical complications rate with Matrix coils was 13.3%. The total rate of recanalization was 11.4%. Large aneurysms treated with combined stenting got 40% recanalization. No statistic relationships were shown between the factors forementioned and the recanalization rate, but progressive occlusion was observed in 11 (61%)incompletely treated aneurysms. Conclusions: Matrix detachable coil technique is safe for intracranial aneurysm and would further decrease the recurrence of large aneurysm with combination of stenting but long term efficacy needs further follow-up and large scale randomized control study. (authors)

  10. Switching transients in a superconducting coil

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1983-01-01

    A study is made of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to performance tests on the MFTF Yin-yang coils. It is found that the breaker opening time is the critical factor in determining the size and shape of the transient. Instantaneous opening of the breaker causes a lightly damped transient with large amplitude voltages to ground. Increasing the opening time causes the transient to become a monopulse of decreasing amplitude. The voltages at the external terminals are determined by the parameters of the external circuit. For fast opening times the frequency depends on the dump resistor inductance, the circuit capacitance, and the amplitude on the coil current. For slower openings the dump resistor inductance and the current determine the amplitude of the voltage to ground at the terminals. Voltages to ground are less in the interior of the coil, where transients related to the parameters of the coil itself are observed

  11. Correcting coils in end magnets of accelerators

    Directory of Open Access Journals (Sweden)

    L. R. P. Kassab

    1998-05-01

    Full Text Available We present an empirical investigation of the correcting coils behavior used to homogenize the field distribution of the race-track microtron accelerator end magnets. These end magnets belong to the second stage of the 30.0 MeV cw electron accelerator under construction at IFUSP, the race-track microtron booster, in which the beam energy is raised from 1.97 to 5.1 MeV. The correcting coils are attached to the pole faces and are based on the inhomogeneities of the magnetic field measured. The performance of these coils, when operating the end magnets with currents that differ by ±10% from the one used in the mappings that originated the coils copper leads, is presented. For one of the magnets, adjusting conveniently the current of the correcting coils makes it possible to homogenize field distributions of different intensities, once their shapes are practically identical to those that originated the coils. For the other one, the shapes are changed and the coils are less efficient. This is related to intrinsic factors that determine the inhomogeneities. However, we obtained uniformity of 0.001% in both cases.

  12. Routine phasing of coiled-coil protein crystal structures with AMPLE

    Directory of Open Access Journals (Sweden)

    Jens M. H. Thomas

    2015-03-01

    Full Text Available Coiled-coil protein folds are among the most abundant in nature. These folds consist of long wound α-helices and are architecturally simple, but paradoxically their crystallographic structures are notoriously difficult to solve with molecular-replacement techniques. The program AMPLE can solve crystal structures by molecular replacement using ab initio search models in the absence of an existent homologous protein structure. AMPLE has been benchmarked on a large and diverse test set of coiled-coil crystal structures and has been found to solve 80% of all cases. Successes included structures with chain lengths of up to 253 residues and resolutions down to 2.9 Å, considerably extending the limits on size and resolution that are typically tractable by ab initio methodologies. The structures of two macromolecular complexes, one including DNA, were also successfully solved using their coiled-coil components. It is demonstrated that both the ab initio modelling and the use of ensemble search models contribute to the success of AMPLE by comparison with phasing attempts using single structures or ideal polyalanine helices. These successes suggest that molecular replacement with AMPLE should be the method of choice for the crystallographic elucidation of a coiled-coil structure. Furthermore, AMPLE may be able to exploit the presence of a coiled coil in a complex to provide a convenient route for phasing.

  13. Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study.

    Science.gov (United States)

    Baseri, Babak; Choi, James J; Tung, Yao-Sheng; Konofagou, Elisa E

    2010-09-01

    As a potentially viable method of brain drug delivery, the safety profile of blood-brain barrier (BBB) opening using focused ultrasound (FUS) and ultrasound contrast agents (UCA) needs to be established. In this study, we provide a short-term (30-min or 5-h survival) histological assessment of murine brains undergoing FUS-induced BBB opening. Forty-nine mice were intravenously injected with Definity microbubbles (0.05 microL/kg) and sonicated under the following parameters: frequency of 1.525 MHz, pulse length of 20 ms, pulse repetition frequency of 10 Hz, peak rarefactional acoustic pressures of 0.15-0.98 MPa and two 30-s sonication intervals with an intermittent 30-s delay. The BBB opening threshold was found to be 0.15-0.3 MPa based on fluorescence and magnetic resonance imaging of systemically injected tracers. Analysis of three histological measures in hematoxylin and eosin-stained sections revealed the safest acoustic pressure to be within the range of 0.3-0.46 MPa in all examined time periods post sonication. Across different pressure amplitudes, only the samples 30 min post opening showed significant difference (p < 0.05) in the average number of distinct damaged sites, microvacuolated sites, dark neurons and sites with extravasated erythrocytes. Enhanced fluorescence around severed microvessels was also noted and found to be associated with the largest tissue effects, whereas mildly diffuse BBB opening with uniform fluorescence in the parenchyma was associated with no or mild tissue injury. Region-specific areas of the sonicated brain (thalamus, hippocampal fissure, dentate gyrus and CA3 area of hippocampus) exhibited variation in fluorescence intensity based on the position, orientation and size of affected vessels. The results of this short-term histological analysis demonstrated the feasibility of a safe FUS-UCA-induced BBB opening under a specific set of sonication parameters and provided new insights on the mechanism of BBB opening.

  14. Internal trim coils for CBA superconducting magnets

    International Nuclear Information System (INIS)

    Thompson, P.A.; Aronson, S.; Cottingham, J.G.; Garber, M.; Hahn, H.; Sampson, W.B.

    1983-01-01

    In order to correct iron saturation effects and shape the beam working line, superconducting trim coils have been constructed, which operate inside the main coils. Detailed studies of mechanical properties, quench behavior, fields produced, and hysteresis have lead to the production of accelerator-quality coils generating the required-strength harmonics up to cos (7theta). These are routinely installed in CBA main magnets and operate at 80% of short sample with negligible training in an ambient field of more than 5.3T

  15. Superconducting coil development and motor demonstration: Overview

    Science.gov (United States)

    Gubser, D. U.

    1995-12-01

    Superconducting bismuth-cuprate wires, coils, and magnets are being produced by industry as part of a program to test the viability of using such magnets in Naval systems. Tests of prototype magnets, coils, and wires reveal progress in commercially produced products. The larger magnets will be installed in an existing superconducting homopolar motor and operated initially at 4.2K to test the performance. It is anticipated that approximately 400 Hp will be achieved by the motor. This article reports on the initial tests of the magnets, coils, and wires as well as the development program to improve their performance.

  16. CS model coil experimental log book

    International Nuclear Information System (INIS)

    Nishijima, Gen; Sugimoto, Makoto; Nunoya, Yoshihiko; Wakabayashi, Hiroshi; Tsuji, Hiroshi

    2001-02-01

    Charging test of the ITER CS Model Coil which is the world's largest superconducting pulse coil and the CS Insert Coil had started at April 11, 2000 and had completed at August 18, 2000. In the campaign, total shot numbers were 356 and the size of the data file in the DAS (Data Acquisition System) was over 20 GB. This report is a database that consists of the log list and the log sheets of every shot. One can access the database, make a search, and browse results via Internet (http://1ogwww.naka.jaeri.go.jp). The database will be useful to quick search to choose necessary shots. (author)

  17. Large magnetic coils for fusion technology

    International Nuclear Information System (INIS)

    Komarek, P.; Ulbricht, A.

    1989-01-01

    This paper reviews the current status of research in this field and outlines future tasks and experiments for the Next European Torus (NET). Research and development work accomplished so far permits generation and safe operation of magnetic fields up to 9 T by means of NbTi coils. Fields up to 11 T are feasible if the coils are cooled with superfluid helium at 1.8 K. The potential of the Nb 3 Sn coils promise achievement of magnetic fields between 12 and 13 T. (MM) [de

  18. Design and Fabrication of the KSTAR Poloidal Field Coil Structure

    International Nuclear Information System (INIS)

    Park, H. K.; Choi, C. H.; Sa, J. W.

    2005-01-01

    The KSTAR magnet system consists of 16 toroidal field(TF) coils. 4 pairs of central solenoid(CS) coils, and 3 pairs of outer poloidal field(PF) coils. The TF coils are encased in a structure to enhance mechanical stability. The CS coil structure is supported on top of the TF coil structure and supplies a vertical compression of 15 MN to prevent lateral movement due to a repulsive force between the CS coils. The PF coil system is vertically symmetry to the machine mid-plane and consists of 6 coils and 80 support structures(i.e, 16 for PF5, 32 for PF6 and 32 fort PF7). All PF coil structures should absorb the thermal contraction difference between TF coil structure and PF coils due to cool down and endure the vertical and radial magnetic forces due to current charging. In order to satisfy these structural requirements. the PF5 coil structure is designed base on hinges and both of PF6 and PF7 coil structures based on flexible plates. The PF coil structures are assembled on the TF coil structure with an individual basement that is welded on the TF coil structure

  19. Small Intracranial Aneurysm Treatment Using Target (®) Ultrasoft (™) Coils.

    Science.gov (United States)

    Jindal, Gaurav; Miller, Timothy; Iyohe, Moronke; Shivashankar, Ravi; Prasad, Vikram; Gandhi, Dheeraj

    2016-06-01

    The introduction of small, soft, complex-shaped microcoils has helped facilitate the endovascular treatment of small intracranial aneurysms (IAs) over the last several years. Here, we evaluate the initial safety and efficacy of treating small IAs using only Target(®) Ultrasoft(™) coils. A retrospective review of a prospectively maintained clinical database at a single, high volume, teaching hospital was performed from September 2011 to May 2015. IAs smaller than or equal to 5.0 mm in maximal dimension treated with only Target(®) Ultrasoft(™) coils were included. A total of 50 patients with 50 intracranial aneurysms were included. Subarachnoid hemorrhage from index aneurysm rupture was the indication for treatment in 23 of 50 (46%) cases, and prior subarachnoid hemorrhage (SAH) from another aneurysm was the indication for treatment in eight of 50 (16%) cases. The complete aneurysm occlusion rate was 70% (35/50), the minimal residual aneurysm rate was 14% (7/50), and residual aneurysm rate was 16% (8/50). One intraoperative aneurysm rupture occurred. Three patients died during hospitalization from clinical sequelae of subarachnoid hemorrhage. Follow-up at a mean of 13.6 months demonstrated complete aneurysm occlusion in 75% (30/40) of cases, near complete occlusion in 15% (6/40) of cases, and residual aneurysm in 10% (4/40) of cases, all four of which were retreated. Our initial results using only Target(®) Ultrasoft(™) coils for the endovascular treatment of small intracranial aneurysms demonstrate initial excellent safety and efficacy profiles.

  20. Flexible eddy current coil arrays

    International Nuclear Information System (INIS)

    Krampfner, Y.; Johnson, D.P.

    1987-01-01

    A novel approach was devised to overcome certain limitations of conventional eddy current testing. The typical single-element hand-wound probe was replaced with a two dimensional array of spirally wound probe elements deposited on a thin, flexible polyimide substrate. This provides full and reliable coverage of the test area and eliminates the need for scanning. The flexible substrate construction of the array allows the probes to conform to irregular part geometries, such as turbine blades and tubing, thereby eliminating the need for specialized probes for each geometry. Additionally, the batch manufacturing process of the array can yield highly uniform and reproducible coil geometries. The array is driven by a portable computer-based eddy current instrument, smartEDDY/sup TM/, capable of two-frequency operation, and offers a great deal of versatility and flexibility due to its software-based architecture. The array is coupled to the instrument via an 80-switch multiplexer that can be configured to address up to 1600 probes. The individual array elements may be addressed in any desired sequence, as defined by the software

  1. A coil test facility for the cryogenic tests of the JT-60SA TF coils

    International Nuclear Information System (INIS)

    Chantant, M.; Genini, L.; Bayetti, P.; Millet, F.; Wanner, M.; Massaut, V.; Corte, A. Della; Ardelier-Desage, F.; Catherine-Dumont, V.; Dael, A.; Decool, P.; Donati, A.; Duchateau, J.L.; Garibaldi, P.; Girard, S.; Hatchressian, J.C.; Fejoz, P.; Jamotton, P.; Jourdheuil, L.; Juster, F.P.

    2011-01-01

    In the framework of the Broader Approach Activities, the EU will deliver to Japan the 18 superconducting coils, which constitute the JT-60SA Toroidal field magnet. These 18 coils, manufactured by France and Italy, will be cold tested before shipping to Japan. For this purpose, the European Joint Undertaking for ITER, the Development of Fusion Energy ('Fusion for Energy', F4E) and the European Voluntary Contributors are collaborating to design and set-up a coil test facility (CTF) and to perform the acceptance test of the 18 JT-60SA Toroidal Field (TF) coils. The test facility is designed to test one coil at a time at nominal current and cryogenic temperature. The test of the first coil of each manufacturer includes a quench triggered by increasing the temperature. The project is presently in the detailed design phase.

  2. Coil measurement data acquisition and curing press control system for SSC dipole magnet coils

    International Nuclear Information System (INIS)

    Dickey, C.E.

    1989-03-01

    A coil matching program, similar in theory to the methods used to match Tevatron coils, is being developed at Fermilab. Modulus of elasticity and absolute coil size will be determined at 18-inch intervals along the coils while in the coil curing press immediately following the curing process. A data acquisition system is under construction to automatically acquire and manage the large quantities of data that result. Data files will be transferred to Fermilab's VAX Cluster for long-term storage and actual coil matching. The data acquisition system will also provide the control algorithm for the curing press hydraulic system. A description of the SSC Curing Press Data Acquisition and Controls System will be reported. 20 figs

  3. Power inverter design for ASDEX Upgrade saddle coils

    Energy Technology Data Exchange (ETDEWEB)

    Teschke, M., E-mail: teschke@ipp.mpg.de [Max Planck Institute for Plasma Physics, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany); Suttrop, W.; Rott, M. [Max Planck Institute for Plasma Physics, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany)

    2013-10-15

    Highlights: ► A cost effective inverter topology for AUG's 16 in-vessel saddle coils has been found. ► Use of commercially available power modules is possible. ► Exchange of reactive power between multiple inverters is possible. ► Influence of electromagnetic noise to AUG's diagnostics was measured. ► Gas insulation of electric feed through significantly depends on magnetic fields. It is protected by fast turn-off circuit. -- Abstract: A set of 16 in-vessel saddle coils has been installed in the ASDEX Upgrade (AUG) experiment since the end of 2011 [1]. To achieve full performance, it is necessary to operate them with alternating current (AC) of arbitrary waveforms. To generate spatially resolved magnetic fields, it is required to allocate separate power inverters to every single coil. Therefore, different topologies are analyzed and compared. Studies of the commutation behavior of power stages, different pulse width modulation (PWM) schemes and single-phase-to-earth fault detection are executed. Experiments to evaluate the electromagnetic interference (EMI) of possible inverter topologies on the AUG diagnostics are done as well. A special focus is put on the feasibility of analyzed topologies using industrially available and fully assembled “power modules” to minimize development effort and costs.

  4. Design considerations for ITER toroidal field coils

    International Nuclear Information System (INIS)

    Kalsi, S.S.; Lousteau, D.C.; Miller, J.R.

    1987-01-01

    The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Europe, Japan, the Union of Soviet Socialist Republics (U.S.S.R.), and the United States. This paper describes a magnetic and mechanical design methodology for toroidal field (TF) coils that employs Nb 3 Sn superconductor technology. Coil winding is sized by using conductor concepts developed for the U.S. TIBER concept. Manifold concepts are presented for the complete cooling system. Also included are concepts for the coil structural arrangement. The effects of in-plane and out-of-plane loads are included in the design considerations for the windings and case. Concepts are presented for reacting these loads with a minimum amount of additional structural material. Concepts discussed in this paper could be considered for the ITER TF coils

  5. 12 tesla test coil. Annual progress report

    International Nuclear Information System (INIS)

    1979-01-01

    The Plasma Fusion Center at MIT has been charged with responsibility for the design, development, fabrication and test operation of a Niobium-3-Tin Superconducting Test Coil. Research is described on DOE's 12 tesla coil demonstration program in which several one-meter diameter superconducting test coils will be inserted and tested in DOE's High Field Test Facility at the Lawrence Livermore Laboratories. The work was initiated at the start of FY 79. FY 79 saw the completion of our Preliminary Design and the initiation of three (3) subcontracts: (1) Westinghouse review of the Preliminary Design, (II) Supercon, Inc. development of a tubular copper matrix, Nb 3 Sn Superconductor and (III) Airco optimization of the LCP-W Nb 3 Sn superconductor for 12T service. In addition, Airco was charged with the production of a 1000 foot length of model 15,000A conductor. Coil winding exercises were initiated at the Everson Electric Company

  6. OCLATOR (One Coil Low Aspect Toroidal Reactor)

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, S.

    1980-02-01

    A new approach to construct a tokamak-type reactor(s) is presented. Basically the return conductors of toroidal field coils are eliminated and the toroidal field coil is replaced by one single large coil, around which there will be placed several tokamaks or other toroidal devices. The elimination of return conductors should, in addition to other advantages, improve the accessibility and maintainability of the tokamaks and offer a possible alternative to the search for special materials to withstand large neutron wall loading, as the frequency of changeover would be increased due to minimum downtime. It also makes it possible to have a low aspect ratio tokamak which should improve the ..beta.. limit, so that a low toroidal magnetic field strength might be acceptable, meaning that the NbTi superconducting wire could be used. This system is named OCLATOR (One Coil Low Aspect Toroidal Reactor).

  7. Advanced Singlet Oxygen Generator for a COIL

    National Research Council Canada - National Science Library

    Kodymova, Jarmila; Zagidullin, M; Nikolaev, V; Svistun, M; Khvatov, N; Hruby, J; Spalek, O; Jirasek, V; Censsky, M

    2005-01-01

    This report results from a contract tasking Academy of Sciences as follows: The Grantee will develop new and radically different ideas for a high performance, advanced singlet oxygen generator for driving a supersonic COIL...

  8. Helium leak testing the Westinghouse LCP coil

    International Nuclear Information System (INIS)

    Merritt, P.A.; Attaar, M.H.; Hordubay, T.D.

    1983-01-01

    The tests, equipment, and techniques used to check the Westinghouse LCP coil for coolant flow path integrity and helium leakage are unique in terms of test sensitivity and application. This paper will discuss the various types of helium leak testing done on the LCP coil as it enters different stages of manufacture. The emphasis will be on the degree of test sensitivity achieved under shop conditions, and what equipment, techniques and tooling are required to achieve this sensitivity (5.9 x 10 -8 scc/sec). Other topics that will be discussed are helium flow and pressure drop testing which is used to detect any restrictions in the flow paths, and the LCP final acceptance test which is the final leak test performed on the coil prior to its being sent for testing. The overall allowable leak rate for this coil is 5 x 10 -6 scc/sec. A general evaluation of helium leak testing experience are included

  9. Radiative MRI Coil Design Using Parasitic Scatterers

    DEFF Research Database (Denmark)

    Sanchez-Heredia, Juan D.; Avendal, Johan; Bibic, Adnan

    2018-01-01

    allows for antenna design techniques to be adapted to RF coil designs. This study proposes the use of parasitic scatterers to improve the performance of an existing 7T MRI coil called the single-sided adapted dipole (SSAD) antenna. The results reveal that scatterers arranged in a Yagi fashion can......Conventionally, radiofrequency (RF) coils used for magnetic resonance imaging (MRI) are electrically small and designed for nearfield operation. Therefore, existing antenna design techniques are mostly irrelevant for RF coils. However, the use of higher frequencies in ultrahigh field (UHF) MRI...... be applied to reduce local specific absorption rate (SAR) maxima of a reference SSAD by 40% with only a 6% decrease in the propagated B1 + field at the tissue depth of 15 cm. The higher directivity of the proposed design also decreasing the coupling with additional elements, making this antenna...

  10. MR angiography after coiling of intracranial aneurysms

    NARCIS (Netherlands)

    Schaafsma, J.D.

    2012-01-01

    Introduction Endovascular occlusion with detachable coils has become an alternative treatment to neurosurgical clipping of intracranial aneurysms over the last two decades. Its minimal invasiveness is the most important advantage of this treatment compared to clipping. The disadvantage of occlusion

  11. Evaluation of SKB's report 'Deep repository for spent nuclear fuel: SR 97 - Post-closure safety', Focusing on the assessment of transport processes in the geosphere

    International Nuclear Information System (INIS)

    Woerman, A.; Shulan Xu

    2000-01-01

    This report describes a critical review of the safety assessment performed on the final repository for nuclear waste in Sweden that is proposed by SKB in 'Deep Repository for Spent Nuclear Fuel: SR 97 - Post-closure Safety'. The review was requested by the Swedish Nuclear Power Inspectorate (SKI). The waste repository consists of several barriers that work together with the purpose of delaying radionuclide migration and reducing the activity that eventually affects the biosphere. A main criticism is the lack of a formal risk analysis and uncertainties in several analyses that make it difficult to comprehend the overall risk of the repository. A formal risk analysis should comprise a probabilistic treatment of all components included in the system. This is not the case in the SKB's report since the probabilistic analyses are limited only to certain aspects. The use of conservative model parameters are not a substitute for risk analysis nor can they compensate for possible model biases. Bias can be expected in most of the existing models of radionuclide migration in fractured bedrock. SKB should present a clear comparison on the importance of the different barrier components (uranium-dioxide matrix, copper canister, buffer and bedrock) on the retardation of radionuclides. It is unclear as to what extent the capacity of the bedrock to retain migrating radionuclides is critical to the capacity of the repository. A large part of the SR 97 report is focused on retardation processes in bedrock and a reader can interpret this as the technical weight given on retardation in the bedrock. However, with the present state of knowledge, it is our opinion that we cannot with an acceptable degree of accuracy predict the radionuclide transport in bedrock or quantify risk levels associated with radioactivity in the biosphere. There are large uncertainties concerning the way by which sorption processes should be formulated and the impact of colloids on the transport that can be

  12. Hypersonic evanescent waves generated with a planar spiral coil.

    Science.gov (United States)

    Stevenson, A C; Araya-Kleinsteuber, B; Sethi, R S; Mehta, H M; Lowe, C R

    2003-09-01

    A planar spiral coil has been used to induce hypersonic evanescent waves in a quartz substrate with the unique ability to focus the acoustic wave down onto the chemical recognition layer. These special sensing conditions were achieved by investigating the application of a radio frequency current to a coaxial waveguide and spiral coil, so that wideband repeating electrical resonance conditions could be established over the MHz to GHz frequency range. At a selected operating frequency of 1.09 GHz, the evanescent wave depth of a quartz crystal hypersonic resonance is reduced to 17 nm, minimising unwanted coupling to the bulk fluid. Verification of the validity of the hypersonic resonance was carried out by characterising the system electrically and acoustically: Impedance calculations of the combined coil and coaxial waveguide demonstrated an excellent fit to the measured data, although above 400 MHz a transition zone was identified where unwanted impedance is parasitic of the coil influence efficiency, so the signal-to-noise ratio is reduced from 3000 to 300. Acoustic quartz crystal resonances at intervals of precisely 13.2138 MHz spacing, from the 6.6 MHz ultrasonic range and onto the desired hypersonic range above 1 GHz, were incrementally detected. Q factor measurements demonstrated that reductions in energy lost from the resonator to the fluid interface were consistent with the anticipated shrinkage of the evanescent wave with increasing operating frequency. Amplitude and frequency reduction in contact with a glucose solution was demonstrated at 1.09 GHz. The complex physical conditions arising at the solid-liquid interface under hypersonic entrainment are discussed with respect to acceleration induced slippage, rupture, longitudinal and shear radiation and multiphase relaxation affects.

  13. Magnetic Test Facility - Sensor and Coil Calibrations

    Science.gov (United States)

    2013-08-01

    amplitude of signals induced into the sensor. 2.1.1.2 Fluxgate magnetometers Fluxgate sensors consist of a ferromagnetic core, around which drive and sense...kHz range to be measured. Fluxgate magnetometers do not have a lower limit to their fre- quency response, and hence can be used to measure...placed within a larger triaxial coil which is used in conjunction with a fluxgate magnetometer to cancel earth’s field at the cen- tre of the coil. A

  14. Quadruple Cone Coil with improved focality than Figure-8 coil in Transcranial Magnetic Stimulation

    Science.gov (United States)

    Rastogi, Priyam; Lee, Erik G.; Hadimani, Ravi L.; Jiles, David C.

    Transcranial Magnetic Stimulation (TMS) is a non-invasive therapy which uses a time varying magnetic field to induce an electric field in the brain and to cause neuron depolarization. Magnetic coils play an important role in the TMS therapy since their coil geometry determines the focality and penetration's depth of the induced electric field in the brain. Quadruple Cone Coil (QCC) is a novel coil with an improved focality when compared to commercial Figure-8 coil. The results of this newly designed QCC coil are compared with the Figure-8 coil at two different positions of the head - vertex and dorsolateral prefrontal cortex, over the 50 anatomically realistic MRI derived head models. Parameters such as volume of stimulation, maximum electric, area of stimulation and location of maximum electric field are determined with the help of computer modelling of both coils. There is a decrease in volume of brain stimulated by 11.6 % and a modest improvement of 8 % in the location of maximum electric field due to QCC in comparison to the Figure-8 coil. The Carver Charitable Trust and The Galloway Foundation.

  15. Magnetic resonance dacryocystography: comparison between conventional surface coils and microscopic coils

    International Nuclear Information System (INIS)

    Abreu Junior, Luiz de; Wolosker, Angela Maria Borri; Borri, Maria Lucia; Galvao Filho, Mario de Melo; Hartmann, Luiz Guilherme de Carvalho; D'Ippolito, Giuseppe; Castro, Claudio Campi de

    2008-01-01

    Objective: Magnetic resonance imaging has been utilized in the evaluation of the lacrimal apparatus with some advantages over conventional dacryocystography. The present study was aimed at acquiring high resolution images utilizing microscopic coils for evaluating typical structures of the lacrimal apparatus as compared with the findings observed with conventional surface coils. Materials and methods: Five asymptomatic volunteers with no history of epiphora were submitted to high-field magnetic resonance imaging with microscopic and conventional surface coils, and STIR sequence after instillation of saline solution. The definition of normal anatomic structures of lacrimal apparatuses was compared utilizing conventional and microscopic surface coils. Based on a consensual scoring system, the mean values for each structure were calculated by two observers. Results: In 90% of cases, higher scores were attributed to images acquired with the microscopic coil. On average, a 1.17 point increase was observed in the scoring of anatomic structures imaged with the microscopic coil. Additionally, a subjective improvement was observed in the signal-to-noise ratio with the microscopic coil. Conclusion: Magnetic resonance dacryocystography with microscopic coils is the appropriate method for evaluating the lacrimal apparatus, providing images with better quality as compared with those acquired with conventional surface coils. (author)

  16. An analysis of 3D solvation structure in biomolecules: application to coiled coil serine and bacteriorhodopsin.

    Science.gov (United States)

    Hirano, Kenji; Yokogawa, Daisuke; Sato, Hirofumi; Sakaki, Shigeyoshi

    2010-06-17

    Three-dimensional (3D) solvation structure around coiled coil serine (Coil-Ser) and inner 3D hydration structure in bacteriorhodopsin (bR) were studied using a recently developed method named multicenter molecular Ornstein-Zernike equation (MC-MOZ) theory. In addition, a procedure for analyzing the 3D solvent distribution was proposed. The method enables us to calculate the coordination number of solvent water as well as the strength of hydrogen bonding between the water molecule and the protein. The results for Coil-Ser and bR showed very good agreement with the experimental observations.

  17. Thomson's Jumping Ring over a Long Coil

    Science.gov (United States)

    Jeffery, Rondo N.; Amiri, Farhang

    2018-01-01

    The classic jumping ring apparatus consists of a coil with an iron core that extends out of the coil. A copper or aluminum ring placed over the iron core jumps upward when AC power is applied to the coil. In this paper we will examine a modified design of the jumping ring apparatus, called the "long-coil design." It allows the ring to…

  18. COMPASS magnetic field coils and structure systems

    International Nuclear Information System (INIS)

    Crossland, R.T.; Booth, J.A.; Hayward, R.J.; Keogh, P.; Pratt, A.P.

    1987-01-01

    COMPASS is a new experimental toroidal assembly of compact design and with a wide range of physics objectives. It is required to operate either as a Tokamak or as a Reversed Field Pinch with interchangeable circular and dee-section vacuum vessels. The Toroidal field is produced by 16 rectangular coils of 4 turns with tapered conductors on the inside which nest together to form a vault to resist the centering forces. The coils are designed to produce a maximum field on axis of 2.1T which requires a current of 91 kA per turn. Two central solenoids and five pairs of coils symmetrically positioned above and below the machine equator provide the poloidal field. Both coil systems are supported form a mechanical support structure which surrounds the machine. This is primarily designed to resist out-of-plane forces on the TF coils but also acts as the base support for the PF coils and vacuum vessels. An illustration of the COMPASS Load Assembly is given and shows the D-shaped vacuum vessel, the major components and the various field windings

  19. Embroidered Coils for Magnetic Resonance Sensors

    Directory of Open Access Journals (Sweden)

    Michael I. Newton

    2013-04-01

    Full Text Available Magnetic resonance imaging is a widely used technique for medical and materials imaging. Even though the objects being imaged are often irregularly shaped, suitable coils permitting the measurement of the radio-frequency signal in these systems are usually made of solid copper. One problem often encountered is how to ensure the coils are both in close proximity and conformal to the object being imaged. Whilst embroidered conductive threads have previously been used as antennae in mobile telecommunications applications, they have not previously been reported for use within magnetic resonance. In this paper we show that an embroidered single loop coil can be used in a commercial unilateral nuclear magnetic resonance system as an alternative to a solid copper. Data is presented showing the determination of both longitudinal (T1 and effective transverse (T2eff relaxation times for a flat fabric coil and the same coil conformed to an 8 cm diameter cylinder. We thereby demonstrate the principles required for the wider use of fabric based conformal coils within nuclear magnetic resonance and magnetic resonance imaging.

  20. Dual levitated coils for antihydrogen production

    Science.gov (United States)

    Wofford, J. D.; Ordonez, C. A.

    2013-04-01

    Two coaxial superconducting magnetic coils that carry currents in the same direction and that are simultaneously levitated may serve for antihydrogen plasma confinement. The configuration may be suitable for use by a collaboration at the CERN Antiproton Decelerator facility to test fundamental symmetries between the properties of hydrogen and antihydrogen. Nested Penning traps are currently used to confine recombining antihydrogen plasma. Symmetry studies require the production of sufficiently cold antihydrogen. However, plasma drifts within nested Penning traps can increase the kinetic energy of antiprotons that form antihydrogen atoms. Dual levitated coils may serve to confine relatively large, cold, dense non-drifting recombining antihydrogen plasmas. A minimum-B magnetic field that is produced by the coils could provide for atom trapping. A toroidal plasma is confined between the coils. High density plasmas may be possible, by allowing plasma pressure to balance mechanical pressure to keep the coils apart. Progress is reported on theoretical and experimental efforts. The theoretical effort includes the development of a classical trajectory Monte Carlo simulation of confinement. The experimental effort includes levitation of a NdFeB permanent ring magnet, which produces a magnetic field that is qualitatively similar to the field that would be produced by the two coaxial superconducting magnetic coils. Liquid-nitrogen-cooled Bi-2223 high-temperature-superconducting components, with a critical temperature of 108 K, were used to levitate the ring magnet. An issue concerning keeping the plane of the levitated ring horizontal is discussed.

  1. [Surface coils for magnetic-resonance images].

    Science.gov (United States)

    Rodríguez-González, Alfredo Odón; Amador-Baheza, Ricardo; Rojas-Jasso, Rafael; Barrios-Alvarez, Fernando Alejandro

    2005-01-01

    Since the introduction of magnetic resonance imaging in Mexico, the development of this important medical imaging technology has been almost non-existing in our country. The very first surface coil prototypes for clinical applications in magnetic resonance imaging has been developed at the Center of Research in Medical Imaging and Instrumentation of the Universidad Autónoma Metropolitana Iztapalapa (Metropolitan Autonomous University, Campus Iztapalapa). Two surface coil prototypes were built: a) a circular-shaped coil and b) a square-shaped coil for multiple regions of the body, such as heart, brain, knee, hands, and ankles. These coils were tested on the 1.5T imager of the ABC Hospital-Tacubaya, located in Mexico City. Brain images of healthy volunteers were obtained in different orientations: sagittal, coronal, and axial. Since images showed a good-enough clinical quality for diagnosis, it is fair to say that these coil prototypes can be used in the clinical environment, and with small modifications, they can be made compatible with almost any commercial scanner. This type of development can offer new alternatives for further collaboration between the research centers and the radiology community, in the search of new applications and developments of this imaging technique.

  2. A design for a high voltage magnet coil ringer test set

    International Nuclear Information System (INIS)

    Koska, W.; Sims, R.E.

    1992-04-01

    By discharging a bank of charged capacitors through a high power SCR switch into an SSC dipole magnet assembly, it is possible to ''ring'' the coil and develop a voltage stress of greater than 50 volts turn-to-turn, thereby verifying the insulation integrity. We will present an overview of the test set design for a 2 kV isolated SCR firing circuit, including safety features, selectable capacitor banks, and digital waveform storage system. Results from testing typical coils and magnets will be included. Possible upgrades are also discussed

  3. Coil supporting device in a nuclear fusion device

    International Nuclear Information System (INIS)

    Takano, Hirohisa; Sasaki, Katsutoki.

    1976-01-01

    Object: To slide a vacuum vessel in the nuclear fusion device and a coil within the vacuum vessel and to mount the coil within the vacuum vessel in a manner that it may not be moved by an electromagnetic force, thereby preventing stress from being produced in the coil. Structure: A coil supporting plate mounted at upper and lower parts prevents damage to an insulation of the coil, said coil being held in a U-shaped groove, and can be moved integral with the coil by the action of a roller bearing with a plurality of needle-like rollers arranged in parallel. The coil supporting plate has a plurality of projections disposed on the lower surface thereof, and flat springs are placed in the projections one over another so that the spring action exerted in the lower plate causes the coil to be resiliently bias in a direction of an electromagnetic force applied thereto and to support the coil. (Yoshino, Y.)

  4. HydroSoft coil versus HydroCoil for endovascular aneurysm occlusion study: A single center experience

    International Nuclear Information System (INIS)

    Guo Xinbin; Fan Yimu; Zhang Jianning

    2011-01-01

    Background and purpose: The HydroCoil Embolic System (HES) was developed to reduce recurrences of aneurysms relative to platinum coils. But the HydroCoil Embolic System was characterized with many limitations. The manufacturer had recognized the challenge and recently a new design of hydrogel-coated coil-HydroSoft has become available in the market as the new generation HydroCoil. We reported our initial experience using HydroSoft coil versus HydroCoil in our center. Methods: 75 aneurysms embolized primarily using HydroSoft Coils from July 2008 to May 2009 were compared with 66 volume- and shape-matched aneurysms treated with HydroCoils from March 2006 to August 2008. Outcome measures included length and number of coils used, contrast volume, and length of hospital stay. During embolization, a stable framework was first established with bare coils, and hydrogel-coated coils were used subsequently to increase the packing density. Follow-up angiographic results 6 months after treatment were evaluated among some of the patients. Results: Successful coil embolization was achieved in all patients. There were no differences in average total coil length used per aneurysm. There were no differences in length of hospital stay and packing density. HydroSoft coils were more suitable using as the finishing or final coil. HydroSoft coil decreased the procedure-related retreated rates, and aneurysm packing was finished with soft, flexible HydroSoft coil and decreased the neck remnant rates. Follow-up angiography in HydroSoft-treated patients at 6 months revealed aneurysm stability without significant residual neck. Conclusions: HydroSoft coil allowed us to deploy coated coils with good packing density. A slight expansion of these coils at the neck can be expected to reduce neck remnant and potentially inhibit recurrence.

  5. Versatile fill coils: initial experience as framing coils for oblong aneurysms. A technical case report.

    Science.gov (United States)

    Osanai, Toshiya; Bain, Mark; Hui, Ferdinand K

    2014-01-01

    Coil embolization of oblong aneurysms is difficult because the majority of commercially available coils are manufactured with a helical or spherical tertiary structure. While adopting framing strategies for oblong aneurysms (aspect ratio ≥ 2: 1), traditional coils may be undersized in the long axis but oversized in the short axis, resulting in increased aneurysmal wall stress, risk of re-rupture, and difficulty creating a basket that respects the aneurysmal neck. We review three cases in which versatile filling coils (VFCs) were used as the initial coils for embolization of oblong aneurysms and report coil distribution characteristics and clinical outcomes. Packing density after VFC implantation was assessed using the software AngioSuite-Neuro edition and AngioCalc. a 58-year-old woman experienced a subarachnoid hemorrhage from a ruptured anterior communicating artery aneurysm (7.5 mm × 3.5 mm). A 3-6 mm × 15 cm VFC was selected as the first coil because the flexibility of its wave-loop structure facilitates framing of an irregularly shaped aneurysm. The loop portions of the structures tend to be pressed to the extremes of the aneurysmal sac by the wave component. The VFC was introduced smoothly into the aneurysmal sac without catheter kickback. We were then able to insert detachable filling coils without any adjunctive technique and achieved complete occlusion. Complete occlusion without severe complications was achieved in all three cases in our study. Average packing density after the first coil was 15.63%. VFC coils may have a specific role in framing oblong aneurysms given their complex loop-wave design, allowing spacing of the coils at the dome and neck while keeping sac stress to a minimum.

  6. Surgical management of an ACM aneurysm eight years after coiling.

    Science.gov (United States)

    Pogády, P; Fellner, F; Trenkler, J; Wurm, G

    2007-04-01

    The authors present a case report on rebleeding of a medial cerebral aneurysm (MCA) eight years after complete endovascular coiling. The primarily successfully coiled MCA aneurysm showed a local regrowth which, however, was not the source of the rebleeding. The angiogram demonstrated no evidence of contrast filling of the coiled segment, but according to intraoperative findings (haematoma location, displacement of coils, evident place of rupture) there is no doubt that the coiled segment of the aneurysm was responsible for the haemorrhage.

  7. Three-axis orthogonal transceiver coil for eddy current sounding

    Science.gov (United States)

    Sukhanov, D.; Zavyalova, K.; Goncharik, M.

    2017-08-01

    We propose the new structure of three-axis transceiver magnetic-induction coil for eddy current probing. Due to the orientation of the coils, the direct signal from the transmitting coil to the receiving coil is minimized, which provided a high dynamic range. Sensitivity in all directions is provided by combining coils of different orientations. Numerical simulation and experimental studies of such a system have been carried out and confirmed the applicability of the proposed method and the mathematical model.

  8. SKEW QUADRUPOLE FOCUSING LATTICES AND APPLICATIONS

    International Nuclear Information System (INIS)

    Parker, B.

    2001-01-01

    In this paper we revisit using skew quadrupole fields in place of traditional normal upright quadrupole fields to make beam focusing structures. We illustrate by example skew lattice decoupling, dispersion suppression and chromatic correction using the neutrino factory Study-II muon storage ring design. Ongoing BNL investigation of flat coil magnet structures that allow building a very compact muon storage ring arc and other flat coil configurations that might bring significant magnet cost reduction to a VLHC motivate our study of skew focusing

  9. Gradient coil system for nuclear magnetic resonance apparatus

    International Nuclear Information System (INIS)

    Frese, G.; Siebold, H.

    1984-01-01

    A gradient coil system for an image-generating, nuclear magnetic resonance tomographic apparatus, particularly a zeugmatographic apparatus. The gradient coil system is arranged on a support body of rotational symmetry, illustratively a hollow cylindrical support body, having an axis which extends along the z-direction of an x, y, z coordinate system which has an origin in the center of imaging region. The gradient coil system contains two pairs of toroidal individual coils which are arranged symmetrically with respect to an x-y plane which extends through the center of the imaging region and which are arranged perpendicular to the z-axis. The direction of current flow in the individual coils of a coil pair is opposite to the direction of flow in the individual coils of the other coil pair. Moreover, further sets of coils are provided for generating field gradient Gx in the x-direction, and Gy in the y-direction. The hollow cylindrical shape of the support body on which the individual coils are arranged permit an imaging region having a substantially spherical volume with a substantially constant field gradient Gz to be achieved. Each of the coils has a predetermined linkage factor which corresponds to the product of the current flowing through the number of coil turns of the coil. Those coils which are arranged further from the plane of symmetry have a substantially larger linkage factor than the coils which are nearer to the plane of symmetry

  10. Imbuing medical professionalism in relation to safety: a study protocol for a mixed-methods intervention focused on trialling an embedded learning approach that centres on the use of a custom designed board game.

    LENUS (Irish Health Repository)

    Ward, Marie

    2017-07-17

    Healthcare organisations have a responsibility for ensuring that the governance of workplace settings creates a culture that supports good professional practice. Encouraging such a culture needs to start from an understanding of the factors that make it difficult for health professionals to raise issues of concern in relation to patient safety. The focus of this study is to determine whether a customised education intervention, developed as part of the study, with interns and senior house officers (SHOs) can imbue a culture of medical professionalism in relation to patient safety and support junior doctors to raise issues of concern, while shaping a culture of responsiveness and learning.

  11. Coil End Optimization of the Nb$_3$Sn Quadrupole for the High Luminosity LHC

    CERN Document Server

    Izquierdo Bermudez, S; Bossert, R; Cheng, D; Ferracin, P; Krave, ST; Perez, J C; Schmalzle, J; Yu, M

    2015-01-01

    As part of the Large Hadron Collider Luminosity upgrade (HiLumi-LHC) program, the US LARP collaboration and CERN are working together to design and build a 150 mm aperture quadrupole magnet that aims at providing a nominal gradient of 140 T/m. The resulting conductor peak field of more than 12 T requires the use of Nb$_{3}$Sn superconducting coils. In this paper the coil design for the quadrupole short model (SQXF) is described, focusing in particular on the optimization of the end-parts. We first describe the magnetic optimization aiming at reducing the peak field enhancement in the ends and minimizing the integrated multipole content. Then we focus on the analysis and tests performed to determine the most suitable shapes of end turns and spacers, minimizing the mechanical stress on the cables. We conclude with a detailed description of the baseline end design for the first series of the short model coils.

  12. Comparison of surface coil and knee coil for evaluation of the patellar cartilage by MR imaging

    International Nuclear Information System (INIS)

    Steen, M. van den; Maeseneer, M. de; Hoste, M.; Vanderdood, K.; Ridder, F. de; Osteaux, M.

    2003-01-01

    Purpose: The aim of this work was to compare the knee coil and the surface coil for the visualisation of the patellar cartilage. Materials and methods: In 28 patients (17 women, 11 men) with an average age of 40 years (range 14-76) with knee pain MR was performed. Transverse images were obtained using a fast spin echo proton density weighted sequence on a Philips Gyroscan Intera 1.5 T clinical system. Transverse images were obtained at the level of the patellar cartilage using both the surface and the knee coil. All images were evaluated by consensus of two radiologists. They evaluated a number of quality criteria on a 4-point scale. Criteria for artefacts were also graded on a 4-point scale. Results: For the visualisation of fluid there was no significant difference between the knee coil and the surface coil (P=0.021). For all other criteria regarding image quality and presence of imaging artefacts there was a significant difference between both coils (P<0.001) with the surface coil obtaining the better result. Conclusion: The use of the surface coil in the visualisation of the patellar cartilage can be recommended at knee MR

  13. Immunogenicity of coiled-coil based drug-free macromolecular therapeutics

    Czech Academy of Sciences Publication Activity Database

    Kverka, Miloslav; Hartley, J.M.; Chu, T.W.; Yang, J.; Heidchen, R.; Kopeček, J.

    2014-01-01

    Roč. 35, č. 2 (2014), s. 5886-5896 ISSN 1616-0177 R&D Projects: GA MŠk(CZ) EE2.3.30.0003 Grant - others:NIH(US) GM095606 Institutional support: RVO:61388971 Keywords : coiled-coil * enantiomers * HPMA copolymer Subject RIV: EC - Immunology

  14. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

    NARCIS (Netherlands)

    Sinka, Rita; Gillingham, Alison K.; Kondylis, Vangelis; Munro, Sean

    2008-01-01

    Vesicles and other carriers destined for the Golgi apparatus must be guided to the correct cisternae. Golgins, long coiled-coil proteins that localize to particular Golgi subdomains via their C termini, are candidate regulators of vesicle sorting. In this study, we report that the GRIP domain

  15. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    International Nuclear Information System (INIS)

    Wang, Xiufang; Nie, Xinyi; Liang, Yilang; Lu, Falong; Yan, Zhongming; Wang, Yu

    2017-01-01

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  16. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xiufang [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Nie, Xinyi [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Liang, Yilang [School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Lu, Falong [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Yan, Zhongming, E-mail: wangxiufanghappy@163.com [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Wang, Yu [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China)

    2017-01-15

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  17. Automated de novo phasing and model building of coiled-coil proteins.

    Science.gov (United States)

    Rämisch, Sebastian; Lizatović, Robert; André, Ingemar

    2015-03-01

    Models generated by de novo structure prediction can be very useful starting points for molecular replacement for systems where suitable structural homologues cannot be readily identified. Protein-protein complexes and de novo-designed proteins are examples of systems that can be challenging to phase. In this study, the potential of de novo models of protein complexes for use as starting points for molecular replacement is investigated. The approach is demonstrated using homomeric coiled-coil proteins, which are excellent model systems for oligomeric systems. Despite the stereotypical fold of coiled coils, initial phase estimation can be difficult and many structures have to be solved with experimental phasing. A method was developed for automatic structure determination of homomeric coiled coils from X-ray diffraction data. In a benchmark set of 24 coiled coils, ranging from dimers to pentamers with resolutions down to 2.5 Å, 22 systems were automatically solved, 11 of which had previously been solved by experimental phasing. The generated models contained 71-103% of the residues present in the deposited structures, had the correct sequence and had free R values that deviated on average by 0.01 from those of the respective reference structures. The electron-density maps were of sufficient quality that only minor manual editing was necessary to produce final structures. The method, named CCsolve, combines methods for de novo structure prediction, initial phase estimation and automated model building into one pipeline. CCsolve is robust against errors in the initial models and can readily be modified to make use of alternative crystallographic software. The results demonstrate the feasibility of de novo phasing of protein-protein complexes, an approach that could also be employed for other small systems beyond coiled coils.

  18. Extrap with iron-cored coils

    International Nuclear Information System (INIS)

    Lehnert, B.

    1985-05-01

    In Extrap configurations there is a high average beta value with respect to the plasma confinement volume. The externally imposed magnetic field which is required for stabilization therefore comes out to have a rather moderate strength, even under expected reactor conditions. As a consequence, this field can be generated not only by conventional external conductor arrangements, but also by iron-cored coils being operated below the saturation limit. A proposal for such iron-cored coil systems is presented in this paper. As compared to conventional conductors, this has the advantage of localizing the magnetic energy of the externally imposed magnetic field mainly to the discharge vessel and the plasma volume, thereby increasing the engineering beta value substantially. Also the problems of the coil stresses and of irradiation of the coils appear to become simplified, as well as replacement of the coil system. A main limitation of this proposal is due to combination of iron core saturation with the required stabilization effect from an ion Larmor radius of sufficient relative magnitude. This limitaion requires further investigation, especially in the full-scale reactor case. Also the modifications of the field geometry by iron core shaping needs further analysis. (Author)

  19. Effects of insulation on potted superconducting coils

    International Nuclear Information System (INIS)

    Zeller, A.F.; DeKamp, J.C.; Magsig, C.T.; Nolen, J.A.; McInturff, A.D.

    1989-01-01

    Test coils using identical wire but with either Formvar or Polyesterimid insulation were fabricated to determine the effects of insulation on training behavior. It was found that the type of insulation did not affect the training behavior. While considerable attention has been paid to epoxy formulations used for superconducting coils, little study has been devoted to the effects of the wire insulation on training behavior. If the insulation does not bind well with the epoxy, the wires will not be held securely in place, and training will be required to make the coil operate at its design limit. In fact, the coil may never reach its design current, showing considerable degredation. Conversely, if the epoxy-insulation reaction is to soften or weaken the insulation, then shorts and/or training may result. The authors have undertaken a study of the effects of the insulation on potted coils wet wound with Stycast 2850 FT epoxy. The wire was insulated with one of two insulting varnishes: Formvar (a polyvinyl formal resin) or Polyesterimid (a phenolic resin). Formvar is the standard insulation in the United States while Polyesterimid the European standard

  20. The design of the SULTAN inner coil

    International Nuclear Information System (INIS)

    Franken, W.M.P.; Spoorenberg, C.J.G.

    1981-12-01

    The background field of the first phase of the test facility SULTAN will be generated by two concentric solenoids: a 6 Tesla outer coil with a free bore of 1.3 m and an inner coil for increasing the field to 8 Tesla. The free bore (cold) will be 1.055 m. The final design of the 8 Tesla inner coil is described. The coil will operate at an overall current density of 23 x 10 6 A/m 2 . It will be cooled directly by forced flow supercritical helium. A hollow conductor is applied, composed of a rectangular copper tube and a 16 strands Rutherford cable, soldered on one side of the tube. The copper tube will be cold worked to cope with the high stress level (165 MPa). The design base (field and stress analysis, cooling, stability), the mechanical design and the instrumentation will be specified. The design and construction of the coil is a part of the collaboration between ECN and Holec Transformer Group

  1. Optimal design for MRI surface coils

    International Nuclear Information System (INIS)

    Rivera, M.; Vaquero, J.J.; Santos, A.; Pozo, F. del; Ruiz-Cabello, J.

    1997-01-01

    To demonstrate the possibility of designing and constructing specific surface coils or antennae for MRI viewing of each particular tissue producing better results than those provided by a general purpose surface coil. The study was performed by the Bioengineering and Telemedicine Group of Madrid Polytechnical University and was carried out at the Pluridisciplinary Institute of the Universidad Complutense in Madrid, using a BMT-47/40 BIOSPEC resonance unit from Bruker. Surface coils were custom-designed and constructed for each region to be studied, and optimized to make the specimen excitation field as homogeneous as possible, in addition to reducing the brightness artifact. First, images were obtained of a round, water phantom measuring 50 mm in diameter, after which images of laboratory rats and rabbits were obtained. The images thus acquired were compared with the results obtained with the coil provided by the manufacturer of the equipment, and were found to be of better quality, allowing the viewing of deeper tissue for the specimen as well as reducing the brightness artifact. The construction of surface coils for viewing specific tissues or anatomical regions improves image quality. The next step in this ongoing project will be the application of these concepts to units designed for use in humans. (Author) 14 refs

  2. Comparison of edge plasma perturbation during ELM control using one vs. two toroidal rows of RMP coils in ITER similar shaped plasmas on DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Fenstermacher, M.E., E-mail: fenstermacher@fusion.gat.co [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States); Evans, T.E.; Osborne, T.H.; Schaffer, M.J.; DeGrassie, J.S.; Gohil, P.; Groebner, R.J. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Moyer, R.A. [University of California, San Diego, 9500 Gilman Dr., La Jolla, California 92093 (United States)

    2009-06-15

    Large Type-I edge localized modes (ELMs) were suppressed by n = 3 resonant magnetic perturbations (RMPs) from a set of internal coils in plasmas with an ITER similar shape at the ITER pedestal collisionality, nu{sub e}*approx0.1 and low edge safety factor (q{sub 95} approx 3.6), with either a single toroidal row of the internal RMP coils or two poloidally separated rows of coils. ELM suppression with a single row of internal coils was achieved at approximately the same q{sub 95} surface-averaged perturbation field as with two rows of coils, but required higher current per coil. Maintaining complete suppression of ELMs using n = 3 RMPs from a single toroidal row of internal coils was less robust to variations in input neutral beam injection torque than previous ELM suppression cases using both rows of internal coils. With either configuration of RMP coils, maximum ELM size is correlated with the width of the edge region having good overlap of the magnetic islands from vacuum field calculations.

  3. Critical current studies of a HTS rectangular coil

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Z. [Department of Engineering, University of Cambridge (United Kingdom); Chudy, M., E-mail: Michal.chudy@stuba.sk [Graduate School of Technology Management, University of Pretoria (South Africa); Institute of Power and Applied Electrical Engineering, Slovak University of Technology in Bratislava (Slovakia); Ruiz, H.S. [Department of Engineering, University of Leicester, Leicester LE1 7RH (United Kingdom); Zhang, X.; Coombs, T. [Department of Engineering, University of Cambridge (United Kingdom)

    2017-05-15

    Highlights: • Unique square pancake coil was manufactured. • Measurements in relatively high magnetic field were performed. • Different sections of the coil were characterized. • Parts of the coil which are limiting critical current were identified. - Abstract: Nowadays, superconducting high field magnets are used in numerous applications due to their superior properties. High temperature superconductors (HTS) are usually used for production of circular pancake or racetrack coils. However different geometries of HTS coils might be required for some specific applications. In this study, the HTS coil wound on a rectangular frame was fully characterized in homogeneous DC background field. The study contains measurements of critical current angular dependencies. The critical current of the entire coil and two selected strands under different magnitudes and orientations of external magnetic fields are measured. The critical regions of the coil in different angular regimes are determined. This study brings better understanding of the in- field performance of HTS coils wound on frames with right-angles.

  4. Fabrication of the KSTAR toroidal field coil structure

    International Nuclear Information System (INIS)

    Choi, C.H.; Sa, J.W.; Park, H.K.; Hong, K.H.; Shin, H.; Kim, H.T.; Bak, J.S.; Lee, G.S.; Kwak, J.H.; Moon, H.G.; Yoon, H.H.; Lee, J.W.; Lee, S.K.; Song, J.Y.; Nam, K.M.; Byun, S.E.; Kim, H.C.; Ha, E.T.; Ahn, H.J.; Kim, D.S.; Lee, J.S.; Park, K.H.; Hong, C.D.

    2005-01-01

    The KSTAR toroidal field (TF) coil structure is under fabrication upon completion of engineering design and prototype construction. The prototype TF coil structure has been fabricated within allowable tolerances. Encasing of the prototype TF coil (TF00) in the prototype structure has been carried out through major processes involving a coil encasing, an enclosing weld, a vacuum pressure impregnation, and an outer surface machining. During the enclosing weld of the TF00 coil structure, we have measured temperatures and stresses on the coil surface. Assembly test had been performed with the TF00 coil structure. We have chosen Type 316LN as material of the TF coil structure. We used the narrow-gap TIG welding method. Doosan Heavy Industries and Construction Company (DHI) will complete the fabrication of the TF coil structure in Feb. 2006. (author)

  5. African fermented dairy products - Overview of predominant technologically important microorganisms focusing on African Streptococcus infantarius variants and potential future applications for enhanced food safety and security.

    Science.gov (United States)

    Jans, Christoph; Meile, Leo; Kaindi, Dasel Wambua Mulwa; Kogi-Makau, Wambui; Lamuka, Peter; Renault, Pierre; Kreikemeyer, Bernd; Lacroix, Christophe; Hattendorf, Jan; Zinsstag, Jakob; Schelling, Esther; Fokou, Gilbert; Bonfoh, Bassirou

    2017-06-05

    Milk is a major source of nutrients, but can also be a vehicle for zoonotic foodborne diseases, especially when raw milk is consumed. In Africa, poor processing and storage conditions contribute to contamination, outgrowth and transmission of pathogens, which lead to spoilage, reduced food safety and security. Fermentation helps mitigate the impact of poor handling and storage conditions by enhancing shelf life and food safety. Traditionally-fermented sour milk products are culturally accepted and widely distributed in Africa, and rely on product-specific microbiota responsible for aroma, flavor and texture. Knowledge of microbiota and predominant, technologically important microorganisms is critical in developing products with enhanced quality and safety, as well as sustainable interventions for these products, including Africa-specific starter culture development. This narrative review summarizes current knowledge of technologically-important microorganisms of African fermented dairy products (FDP) and raw milk, taking into consideration novel findings and taxonomy when re-analyzing data of 29 publications covering 25 products from 17 African countries. Technologically-important lactic acid bacteria such as Lactococcus lactis and Streptococcus infantarius subsp. infantarius (Sii), Lactobacillus spp. and yeasts predominated in raw milk and FDP across Africa. Re-analysis of data also suggests a much wider distribution of Sii and thus a potentially longer history of use than previously expected. Therefore, evaluating the role and safety of African Sii lineages is important when developing interventions and starter cultures for FDP in Africa to enhance food safety and food security. In-depth functional genomics, epidemiologic investigations and latest identification approaches coupled with stakeholder involvement will be required to evaluate the possibility of African Sii lineages as novel food-grade Streptococcus lineage. Copyright © 2017 The Authors. Published by

  6. The role of Aboriginal family workers in delivering a child safety focused home visiting program for Aboriginal families in an urban region of NSW.

    Science.gov (United States)

    Clapham, Kathleen; Bennett-Brook, Keziah; Hunter, Kate

    2018-05-09

    Aboriginal Australian children experience higher rates of injury than other Australian children. However few culturally acceptable programs have been developed or evaluated. The Illawarra Aboriginal Medical Service (IAMS) developed the Safe Homes Safe Kids program as an injury prevention program targeting disadvantaged Aboriginal families with children aged 0-5 in an urban region of NSW. Delivered by Aboriginal Family Workers the program aims to reduce childhood injury by raising awareness of safety in the home. A program evaluation was conducted to determine the effectiveness of the home visiting model as an injury prevention program. This paper reports on the qualitative interviews which explored the ways in which clients, IAMS staff, and external service providers experienced the program and assessed its delivery by the Aboriginal Family Workers. A qualitative program evaluation was conducted between January 2014 and June 2015. We report here on the semi-structured interviews undertaken with 34 individuals. The results show increased client engagement in the program; improved child safety knowledge and skills; increased access to services; improved attitudes to home and community safety; and changes in the home safety environment. Safe Homes Safe Kids provides a culturally appropriate child safety program delivered by Aboriginal Family Workers to vulnerable families. Clients, IAMS staff, and external service were satisfied with the family workers' delivery of the program and the holistic model of service provision. SO WHAT?: This promising program could be replicated in other Aboriginal health services to address unintentional injury to vulnerable Aboriginal children. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  7. CS model coil experimental log book

    Energy Technology Data Exchange (ETDEWEB)

    Nishijima, Gen; Sugimoto, Makoto; Nunoya, Yoshihiko; Wakabayashi, Hiroshi; Tsuji, Hiroshi [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2001-02-01

    Charging test of the ITER CS Model Coil which is the world's largest superconducting pulse coil and the CS Insert Coil had started at April 11, 2000 and had completed at August 18, 2000. In the campaign, total shot numbers were 356 and the size of the data file in the DAS (Data Acquisition System) was over 20 GB. This report is a database that consists of the log list and the log sheets of every shot. One can access the database, make a search, and browse results via Internet (http://1ogwww.naka.jaeri.go.jp). The database will be useful to quick search to choose necessary shots. (author)

  8. OCLATOR (One Coil Low Aspect Toroidal Reactor)

    International Nuclear Information System (INIS)

    Yoshikawa, S.

    1980-02-01

    A new approach to construct a tokamak-type reactor(s) is presented. Basically the return conductors of toroidal field coils are eliminated and the toroidal field coil is replaced by one single large coil, around which there will be placed several tokamaks or other toroidal devices. The elimination of return conductors should, in addition to other advantages, improve the accessibility and maintainability of the tokamaks and offer a possible alternative to the search for special materials to withstand large neutron wall loading, as the frequency of changeover would be increased due to minimum downtime. It also makes it possible to have a low aspect ratio tokamak which should improve the β limit, so that a low toroidal magnetic field strength might be acceptable, meaning that the NbTi superconducting wire could be used. This system is named OCLATOR

  9. MFTF test coil construction and performance

    International Nuclear Information System (INIS)

    Cornish, D.N.; Zbasnik, J.P.; Leber, R.L.; Hirzel, D.G.; Johnston, J.E.; Rosdahl, A.R.

    1978-01-01

    A solenoid coil, 105 cm inside the 167 cm outside diameter, has been constructed and tested to study the performance of the stabilized Nb--Ti conductor to be used in the Mirror Fusion Test Facility (MFTF) being built at Lawrence Livermore Laboratory. The insulation system of the test coil is identical to that envisioned for MFTF. Cold-weld joints were made in the conductor at the start and finish of each layer; heaters were fitted to some of these joints and also to the conductor at various locations in the winding. This paper gives details of the construction of the coil and the results of the tests carried out to determine its propagation and recovery characteristics

  10. Considerations against a force compensated coil

    International Nuclear Information System (INIS)

    Hassenzahl, W.

    1988-08-01

    The cost of structural components in a large superconducting coil may well exceed the coil and cryostat cost. As a result, the idea of constructing a system composed of two different coil types assembled in such a way that the sources balance and reduce the total structural requirement is oft proposed. A suitable geometry has never been found for the fundamental reason that there can be no force compensated solution. In this paper, the general problem is presented and an analysis of the energy stored and stresses produced in the structure are described in a fundamental way. Finally, the relation between structural mass M and stored energy E, M ≥/rho/E/σ/sub w/, that is valid for all magnetic systems is developed, where /rho/ is the density of the structure and σ/sub w/ is the working stress in the structure. 12 refs., 2 figs

  11. Considerations against a force compensated coil

    International Nuclear Information System (INIS)

    Hassenzahl, W.

    1988-08-01

    The cost of structural components in a large superconducting coil may well exceed the coil and cryostat cost. As a result, the idea of constructing a system composed of two different coil types assembled in such a way that the forces balance and reduce the total structural requirement is oft proposed. A suitable geometry has never been found for the fundamental reason that there can be no force compensated solution. In this paper, the general problem is presented and an analysis of the energy stored and stresses produced in the structure are described in a fundamental way. Finally, the relation between structural mass M and stored energy E, M ≥ /rho/E/σ/sub w/, that is valid for all magnetic systems is developed, where /rho/ is the density of the structure and σ/sub w/ is the working stress in the structure. 8 refs., 2 figs

  12. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu

    2014-11-13

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  13. Isabelle dipole and quadrupole coil configurations

    International Nuclear Information System (INIS)

    Dahl, P.F.; Hahn, H.

    1980-01-01

    The coil configurations of the ISABELLE dipole and quadrupole magnets have been reviewed and a number of improvements were suggested for incorporation into the final design. The coil designs are basically single layer multiple block approximations to cosine current distributions, wound from a high aspect ratio non-keystoned braided conductor. The blocks are separated by knife-edge wedges to maximize the quench propagation velocity. The current density variation is obtained by an appropriate distribution of the spacer turns and, to a lesser degree, by the wedge locations. The use of inert turns is necessary to minimize the peak field enhancement both in the ends and in the two dimensional section. Schemes for deriving turns distributions yielding harmonic coefficients satisfying the stringent ISABELLE tolerances on field uniformity, while allowing for simplicity in winding and taking into account quench propagation considerations, will be discussed, as well as our approach to the coil end configuration

  14. FRC translation into a compression coil

    International Nuclear Information System (INIS)

    Chrien, R.E.

    1985-01-01

    Several features of the problem of FRC translation into a compression coil are considered. First, the magnitude of the guide field is calculated and found to exceed that which would be applied to a flux conserver. Second, energy conservation is applied to FRC translation from a flux conserver into a compression coil. It is found that a significant temperature decrease is required for translation to be energetically possible. The temperature change depends on the external inductance in the compression circuit. An analogous case is that of a compression region composed of a compound magnet; in this case the temperature change depends on the ratio of inner and outer coil radii. Finally, the kinematics of intermediate translation states are calculated using an ''abrupt transition'' model. It is found, in this model, that the FRC must overcome a potential hill during translation, which requires a small initial velocity

  15. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu; Wu, Ying; Chen, Ze-Guo; Zheng, Li-Yang; Xu, Ye-Long; Nayar, Priyanka; Liu, Xiao-Ping; Lu, Ming-Hui; Chen, Yan-Feng

    2014-01-01

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  16. High voltage investigations for ITER coils

    International Nuclear Information System (INIS)

    Fink, S.; Fietz, W.H.

    2006-01-01

    The superconducting ITER magnets will be excited with high voltage during operation and fast discharge. Because the coils are complex systems the internal voltage distribution can differ to a large extent from the ideal linear voltage distribution. In case of fast excitations internal voltages between conductor and radial plate of a TF coil can be even higher than the terminal voltage of 3.5 kV to ground which appears during a fast discharge without a fault. Hence the determination of the transient voltage distribution is important for a proper insulation co-ordination and will provide a necessary basis for the verification of the individual insulation design and the choice of test voltages and waveforms. Especially the extent of internal overvoltages in case of failures, e. g. malfunction of discharge units and / or arcing is of special interest. Transient calculations for the ITER TF coil system have been performed for fast discharge and fault scenarios to define test voltages for ITER TF. The conductor and radial plate insulation of the ITER TF Model Coil were exposed at room temperature to test voltages derived from the results from these calculations. Breakdown appeared during the highest AC voltage step. A fault scenario for the TF fast discharge system is presented where one fault triggers a second fault, leading to considerable voltage stress. In addition a FEM model of Poloidal Field Coil 3 for the determination of the parameters of a detailed network model is presented in order to prepare detailed investigations of the transient voltage behaviour of the PF coils. (author)

  17. A measure of acoustic noise generated from transcranial magnetic stimulation coils.

    Science.gov (United States)

    Dhamne, Sameer C; Kothare, Raveena S; Yu, Camilla; Hsieh, Tsung-Hsun; Anastasio, Elana M; Oberman, Lindsay; Pascual-Leone, Alvaro; Rotenberg, Alexander

    2014-01-01

    The intensity of sound emanating from the discharge of magnetic coils used in repetitive transcranial magnetic stimulation (rTMS) can potentially cause acoustic trauma. Per Occupational Safety and Health Administration (OSHA) standards for safety of noise exposure, hearing protection is recommended beyond restricted levels of noise and time limits. We measured the sound pressure levels (SPLs) from four rTMS coils with the goal of assessing if the acoustic artifact levels are of sufficient amplitude to warrant protection from acoustic trauma per OSHA standards. We studied the SPLs at two frequencies (5 and 10 Hz), three machine outputs (MO) (60, 80 and 100%), and two distances from the coil (5 and 10 cm). We found that the SPLs were louder at closer proximity from the coil and directly dependent on the MO. We also found that in all studied conditions, SPLs were lower than the OSHA permissible thresholds for short (8 h) exposure. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Study of electric phenomena in energy dumping of LCT coil

    International Nuclear Information System (INIS)

    Oka, Koichi; Tsuji, Hiroshi; Nishi, Masataka; Shimamoto, Susumu

    1980-03-01

    In IEA-LCT coil, electric phenomena in energy dumping were studied analytically and experimentally. Protection resistance of the Japanese LCT coil is chosen as 0.1 Ω considering the quenching voltage, so that temperature rise of the coil is no problem. Energy dumping characteristic of the six-coil system is calculated under different conditions. It is concluded that simultaneous dumping of all the coils with the equivalent resistance values of protection is necessary. Flashover voltage tests of the model in 4.2 K liquid helium, 4.2 K gas helium and 4.2 K boiling helium show margin in practical quenching voltage of the coil. (author)

  19. Resistive demountable toroidal-field coils for tokamak reactors

    International Nuclear Information System (INIS)

    Jassby, D.L.; Jacobsen, R.A.; Kalnavarns, J.; Masson, L.S.; Sekot, J.P.

    1981-07-01

    Readily demountable TF (toroidal-field) coils allow complete access to the internal components of a tokamak reactor for maintenance of replacement. The requirement of readily demountable joints dictates the use of water-cooled resistive coils, which have a host of decisive advantages over superconducting coils. Previous papers have shown that resistive TF coils for tokamak reactors can operate in the steady state with acceptable power dissipation (typically, 175 to 300 MW). This paper summarizes results of parametric studies of size optimization of rectangular TF coils and of a finite-element stress analysis, and examines several candidate methods of implementing demountable joints for rectangular coils constructed of plate segments

  20. Stress distributions of coils for toroidal magnetic field

    International Nuclear Information System (INIS)

    Kajita, Tateo; Miyamoto, Kenro.

    1976-01-01

    The stress distributions of a D shaped coil and a circular coil are computed by the finite element method. The dependences of the stress distribution on the geometrical parameters of the stress distribution on the geometrical parameters of the coils and supporting methods are examined. The maximum amount of the stress in the D shaped coil is not much smaller than that of the circular one. However, the stress distribution of the D shaped coil becomes much more uniform. The supporting method has as much effect as the geometrical parameters of the coil on the stress distribution. (auth.)

  1. Zero current measurements using the Rogowski coil

    International Nuclear Information System (INIS)

    Gregor, J.; Jakubova, I.; Kadlec, P.; Senk, J.; Vavra, Z.

    1997-01-01

    The zero current measurements using the Rogowski coil carried out on the model of the extinguishing chamber of hv SF 6 circuit breaker with self-flow generation are presented in the paper. The time course of the post-arc current obtained by numerical integration of the measured induced voltage of the Rogowski coil gives information not only about the value of the residual current after the successful interruption but also about the current changes connected with the dynamic behaviour of the arc during its quenching. (author)

  2. Self-assembling segmented coiled tubing

    Science.gov (United States)

    Raymond, David W.

    2016-09-27

    Self-assembling segmented coiled tubing is a concept that allows the strength of thick-wall rigid pipe, and the flexibility of thin-wall tubing, to be realized in a single design. The primary use is for a drillstring tubular, but it has potential for other applications requiring transmission of mechanical loads (forces and torques) through an initially coiled tubular. The concept uses a spring-loaded spherical `ball-and-socket` type joint to interconnect two or more short, rigid segments of pipe. Use of an optional snap ring allows the joint to be permanently made, in a `self-assembling` manner.

  3. Multiple coil closure of isolated aortopulmonary collateral

    Directory of Open Access Journals (Sweden)

    Padhi Sumanta

    2010-01-01

    Full Text Available A 7-month-old girl was diagnosed to have large aortopulmonary collateral during evaluation for congestive heart failure. There was no other evidence of cardiopulmonary disease. The collateral was successfully closed with multiple coils delivered sequentially. We describe the issues associated during closure of the aortopulmonary collateral in this case. To the best of our knowledge, this is the first reported case of large aortopulmonary collateral presenting with heart failure in an otherwise structurally normal heart that was closed successfully with multiple coils delivered sequentially.

  4. A new type of coil structure called pan-shaped coil of wireless charging system based on magnetic resonance

    Science.gov (United States)

    Yue, Z. K.; Liu, Z. Z.; Hou, Y. J.; Zeng, H.; Liang, L. H.; Cui, S.

    2017-11-01

    The problem that misalignment between the transmitting coil and the receiving coil significantly impairs the transmission power and efficiency of the system has been attached more and more attention. In order to improve the uniformity of the magnetic field between the two coils to solve this problem, a new type of coil called pan-shaped coil is proposed. Three-dimension simulation models of the planar-core coil and the pan-shaped coil are established using Ansoft Maxwell software. The coupling coefficient between the transmitting coil and the receiving coil is obtained by simulating the magnetic field with the receiving coil misalignment or not. And the maximum percentage difference strength along the radial direction which is defined as the magnetic field uniformity factor is calculated. According to the simulation results of the two kinds of coil structures, it is found that the new type of coil structure can obviously improve the uniformity of the magnetic field, coupling coefficient and power transmission properties between the transmitting coil and the receiving coil.

  5. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions

    International Nuclear Information System (INIS)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in 1 H- 15 N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by 1 H- 15 N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies

  6. Fine-tuning of protein domain boundary by minimizing potential coiled coil regions.

    Science.gov (United States)

    Iwaya, Naoko; Goda, Natsuko; Unzai, Satoru; Fujiwara, Kenichiro; Tanaka, Toshiki; Tomii, Kentaro; Tochio, Hidehito; Shirakawa, Masahiro; Hiroaki, Hidekazu

    2007-01-01

    Structural determination of individual protein domains isolated from multidomain proteins is a common approach in the post-genomic era. Novel and thus uncharacterized domains liberated from intact proteins often self-associate due to incorrectly defined domain boundaries. Self-association results in missing signals, poor signal dispersion and a low signal-to-noise ratio in (1)H-(15)N HSQC spectra. We have found that a putative, non-canonical coiled coil region close to a domain boundary can cause transient hydrophobic self-association and monomer-dimer equilibrium in solution. Here we propose a rational method to predict putative coiled coil regions adjacent to the globular core domain using the program COILS. Except for the amino acid sequence, no preexisting knowledge concerning the domain is required. A small number of mutant proteins with a minimized coiled coil region have been rationally designed and tested. The engineered domains exhibit decreased self-association as assessed by (1)H-(15)N HSQC spectra with improved peak dispersion and sharper cross peaks. Two successful examples of isolating novel N-terminal domains from AAA-ATPases are demonstrated. Our method is useful for the experimental determination of domain boundaries suited for structural genomics studies.

  7. On the application of High-Tc superconductors in power coils and transformers

    NARCIS (Netherlands)

    Chevtchenko, O.A.

    2002-01-01

    In this study, the electro-magnetic properties of high-Tc tapes and coils are investigated. The focus is on Bi-2223/Ag tapes with non-twisted superconducting filaments as these are the only high-Tc superconductors at present available in sufficient length for practical applications. The study is

  8. Research on the Heating of Deicing Fluid in a New Reshaped Coiled Tube

    Directory of Open Access Journals (Sweden)

    Mengli Wu

    2017-01-01

    Full Text Available Aircraft ground deicing operation is significant to ensure civil flight safety in winter. Helically coiled tube is the important heat exchanger in Chinese deicing fluid heating system. In order to improve the deicing efficiency, the research focuses on heat transfer enhancement of deicing fluid in the tube. Based on the field synergy principle, a new reshaped tube (TCHC is designed by ring-rib convex on the inner wall. Deicing fluid is high viscosity ethylene-glycol-based mixture. Because of the power function relation between high viscosity and temperature, viscosity has a negative influence on heat transfer. The number of ring-ribs and inlet velocity are two key parameters to the heat transfer performance. For both water and ethylene glycol, the outlet temperature rises when the number of ring-ribs increases to a certain limit. However, the increasing of velocity reduces heating time, which results in lower outlet temperature. The heating experiment of the original tube is conducted. The error between experiment and simulation is less than 5%. The outlet temperature of TCHC increases by 3.76%. As a result, TCHC efficiently promotes the coordination of velocity and temperature fields by changing the velocity field. TCHC has enhanced heat transfer of high viscosity deicing fluid.

  9. Regulatory risks associated with nuclear safety legislation after Fukushima Daiichi Nuclear Accident in Japan. Focus on legal structure of the nuclear reactor regulation act

    International Nuclear Information System (INIS)

    Tanabe, Tomoyuki; Maruyama, Masahiro

    2016-01-01

    Nuclear safety regulations enforced after Fukushima Daiichi Nuclear Accident under the Nuclear Reactor Regulation Act face the following regulatory problems that involve potential risk factors for nuclear businesses; 1) 'entity based regulation' unable to cope with business cessation or bankruptcy of the entity subject of regulation, 2) potential risk of the Nuclear Regulation Authority's inappropriate involvement in nuclear industry policy beyond their duty, and 3) compliance of backfits under vague regulations. In order to alleviate them, this report, through analyzing these regulatory problems from the view point of sound development of the nuclear industry, proposes the following regulatory reforms; (1) To clarify the rule for industry policy in nuclear regulations and enable the authority, Ministry of Economy, Trade and Industry, to choose most appropriate industrial policy measure. (2) Through establishing safety goals as measures to promote continuous improvement of nuclear safety regulations, to stimulate timely adjustments of the regulations, and to introduce a legal mechanism into the nuclear regulation systems under which validity of administrative law and its application can be checked. (author)

  10. Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.

    Directory of Open Access Journals (Sweden)

    Meier Iris

    2002-04-01

    Full Text Available Abstract Background Animal and yeast proteins containing long coiled-coil domains are involved in attaching other proteins to the large, solid-state components of the cell. One subgroup of long coiled-coil proteins are the nuclear lamins, which are involved in attaching chromatin to the nuclear envelope and have recently been implicated in inherited human diseases. In contrast to other eukaryotes, long coiled-coil proteins have been barely investigated in plants. Results We have searched the completed Arabidopsis genome and have identified a family of structurally related long coiled-coil proteins. Filament-like plant proteins (FPP were identified by sequence similarity to a tomato cDNA that encodes a coiled-coil protein which interacts with the nuclear envelope-associated protein, MAF1. The FPP family is defined by four novel unique sequence motifs and by two clusters of long coiled-coil domains separated by a non-coiled-coil linker. All family members are expressed in a variety of Arabidopsis tissues. A homolog sharing the structural features was identified in the monocot rice, indicating conservation among angiosperms. Conclusion Except for myosins, this is the first characterization of a family of long coiled-coil proteins in plants. The tomato homolog of the FPP family binds in a yeast two-hybrid assay to a nuclear envelope-associated protein. This might suggest that FPP family members function in nuclear envelope biology. Because the full Arabidopsis genome does not appear to contain genes for lamins, it is of interest to investigate other long coiled-coil proteins, which might functionally replace lamins in the plant kingdom.

  11. Characteristics of bowl-shaped coils for transcranial magnetic stimulation

    Science.gov (United States)

    Yamamoto, Keita; Suyama, Momoko; Takiyama, Yoshihiro; Kim, Dongmin; Saitoh, Youichi; Sekino, Masaki

    2015-05-01

    Transcranial magnetic stimulation (TMS) has recently been used as a method for the treatment of neurological and psychiatric diseases. Daily TMS sessions can provide continuous therapeutic effectiveness, and the installation of TMS systems at patients' homes has been proposed. A figure-eight coil, which is normally used for TMS therapy, induces a highly localized electric field; however, it is challenging to achieve accurate coil positioning above the targeted brain area using this coil. In this paper, a bowl-shaped coil for stimulating a localized but wider area of the brain is proposed. The coil's electromagnetic characteristics were analyzed using finite element methods, and the analysis showed that the bowl-shaped coil induced electric fields in a wider area of the brain model than a figure-eight coil. The expanded distribution of the electric field led to greater robustness of the coil to the coil-positioning error. To improve the efficiency of the coil, the relationship between individual coil design parameters and the resulting coil characteristics was numerically analyzed. It was concluded that lengthening the outer spherical radius and narrowing the width of the coil were effective methods for obtaining a more effective and more uniform distribution of the electric field.

  12. Ring coil optimization with respect to stress, temperature, and system energy over a range of physics requirements

    International Nuclear Information System (INIS)

    Pillsbury, R.D. Jr; Thome, R.J.

    1987-01-01

    The poloidal field coil system for a tokamak can be divided into the central solenoid and the ring coils. A ring coil is defined as one that has a small cross-section compared to its diameter. The size of the central solenoid is usually fixed very early in the design process since its size is directly related to the tokamak size. The sizes of the other (ring) coils are not as critical to determining the basic machine size. It is necessary to know their locations and currents in order to verify the shaping and position control of the plasma. Attention is usually focused only on the baseline plasma of the design point. However, the PF set must also be able to shape and maintain other plasmas. This paper describes a program which evaluates PF coil current scenarios over a range of physics requirements and determines the sizes of the coils necessary to satisfy constraints on the temperature rise and stress levels for the worst case scenario. In addition, the system energy requirements can be assessed and trade-offs between system energy and coil sizes (cost) can be made. Examples are given based on studies performed of CIT (Compact Ignition Tokamak)

  13. TEXT poloidal coil systems power supplies

    International Nuclear Information System (INIS)

    Hutchins, S.H.; Brower, D.F.

    1977-01-01

    TEXT is a convertional iron core tokamak which will have a toroidal field of 3.0 Tesla produced by room temperature copper coils and a maximum plasma current pulse of 400 kA induced by a 40 turn Ohmic Heating coil. The major radius is 100 cm and the minor radius of the plasma is 28 cm. The machine is intended for basic research in tokamak plasma physics and atomic physics and is designed primarily to provide a stable hot plasma, extremely good diagnostic access, and reliable operation. The discharge pulse length will be 300 msec and the repetition period 120 seconds. Power for the toroidal field coils and for the ohmic heating supply is provided by a 100 MVA energy storage alternator. The vertical field, horizontal field, fast positioning, and discharge cleaning power supply systems are powered from the Tokamak Laboratory power mains. The ohmic heating power system consists of an SCR controlled premagnetizing supply and commutation circuit, the main ohmic heating capacitor bank to provide plasma breakdown and current rise, and an SCR controlled power supply which sustains plasma current during the 300 ms pulse. The vertical field power system uses a small capacitor bank and an SCR controlled supply. The horizontal field has a reversible SCR controlled supply, and the fast positioning coils are powered by bipolar output transistor controlled supplies. This paper describes the loads, required wave forms, and the specifications for these power supply systems

  14. Coiling of ruptured pericallosal artery aneurysms.

    NARCIS (Netherlands)

    Menovsky, T.; Rooij, W.J.J. van; Sluzewski, M.; Wijnalda, D.

    2002-01-01

    OBJECTIVE: To assess the technical feasibility of treating ruptured pericallosal artery aneurysms with detachable coils and to evaluate the anatomic and clinical results. METHODS: Over a period of 27 months, 12 patients with a ruptured pericallosal artery aneurysm were treated with detachable

  15. Transcatheter Coil Embolization of Splenic Artery Aneurysm

    International Nuclear Information System (INIS)

    Yamamoto, Satoshi; Hirota, Shozo; Maeda, Hiroaki; Achiwa, Sachiko; Arai, Keisuke; Kobayashi, Kaoru; Nakao, Norio

    2008-01-01

    The purpose of this study was to evaluate clinical results and technical problems of transcatheter coil embolization for splenic artery aneurysm. Subjects were 16 patients (8 men, 8 women; age range, 40-80 years) who underwent transcatheter embolization for splenic artery aneurysm (14 true aneurysms, 2 false aneurysms) at one of our hospitals during the period January 1997 through July 2005. Two aneurysms (12.5%) were diagnosed at the time of rupture. Multiple splenic aneurysms were found in seven patients. Aneurysms were classified by site as proximal (or strictly ostial) (n = 3), middle (n = 3), or hilar (n = 10). The indication for transcatheter arterial embolization was a false or true aneurysm 20 mm in diameter. Embolic materials were fibered coils and interlocking detachable coils. Embolization was performed by the isolation technique, the packing technique, or both. Technically, all aneurysms were devascularized without severe complications. Embolized aneurysms were 6-40 mm in diameter (mean, 25 mm). Overall, the primary technical success rate was 88% (14 of 16 patients). In the remaining 2 patients (12.5%), partial recanalization occurred, and re-embolization was performed. The secondary technical success rate was 100%. Seven (44%) of the 16 study patients suffered partial splenic infarction. Intrasplenic branching originating from the aneurysm was observed in five patients. We conclude that transcatheter coil embolization should be the initial treatment of choice for splenic artery aneurysm

  16. Stellarator Coil Design and Plasma Sensitivity

    International Nuclear Information System (INIS)

    Ku, Long-Poe; Boozer, Allen H.

    2010-01-01

    The rich information contained in the plasma response to external magnetic perturbations can be used to help design stellarator coils more effectively. We demonstrate the feasibility by first devel oping a simple, direct method to study perturbations in stellarators that do not break stellarator symmetry and periodicity. The method applies a small perturbation to the plasma boundary and evaluates the resulting perturbed free-boundary equilibrium to build up a sensitivity matrix for the important physics attributes of the underlying configuration. Using this sensitivity information, design methods for better stellarator coils are then developed. The procedure and a proof-of-principle application are given that (1) determine the spatial distributions of external normal magnetic field at the location of the unperturbed plasma boundary to which the plasma properties are most sen- sitive, (2) determine the distributions of external normal magnetic field that can be produced most efficiently by distant coils, (3) choose the ratios of the magnitudes of the the efficiently produced magnetic distributions so the sensitive plasma properties can be controlled. Using these methods, sets of modular coils are found for the National Compact Stellarator Experiment (NCSX) that are either smoother or can be located much farther from the plasma boundary than those of the present design.

  17. High-field superconducting nested coil magnet

    Science.gov (United States)

    Laverick, C.; Lobell, G. M.

    1970-01-01

    Superconducting magnet, employed in conjunction with five types of superconducting cables in a nested solenoid configuration, produces total, central magnetic field strengths approaching 70 kG. The multiple coils permit maximum information on cable characteristics to be gathered from one test.

  18. Coil in bottom part of splitter magnet

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    Radiation-resistant coil being bedded into the bottom part of a splitter magnet. This very particular magnet split the beam into 3 branches, for 3 target stations in the West-Area. See Annual Report 1975, p.176, Figs.14 and 15.

  19. FRC translation into a compression coil

    International Nuclear Information System (INIS)

    Chrien, R.E.

    1986-01-01

    The equilibrium and translational kinematics of Field-Reversed Configurations (FRCs) in a cylindrical coil which does not conserve flux are problems that arise in connection with adiabatic compressional heating. In this paper, they consider several features of the problem of FRC translation into a compression coil. First, the magnitude of the guide field is calculated and found to exceed that which would be applied to a flux conserver. Second, energy conservation is applied to FRC translation from a flux conserver into a compression coil. It is found that a significant temperature decrease is required for translation to be energetically possible. The temperature change depends on the external inductance in the compression circuit. An analogous case is that of a compression region composed of a compound magnet; in this case the temperature change depends on the ratio of inner and outer coil radii. Finally, the kinematics of intermediate translation states are calculated using an abrupt transition model. It is found, in this model, that the FRC must overcome a potential hill during translation, which requires a small initial velocity

  20. Traveling-wave synchronous coil gun

    International Nuclear Information System (INIS)

    Elliott, D.G.

    1991-01-01

    This paper reports on a traveling-wave synchronous coil gun which permits independent adjustment of the magnetic field and armature current for high velocity at low armature mass fraction. Magnetic field energy is transferred from the rear of the wave to the front without passing through the power supply. Elaborate switching is required

  1. Thermal, Electrical and Mechanical Response to a Quench in Nb3Sn Superconducting Coils

    International Nuclear Information System (INIS)

    Ferracin, F.; Caspi, S.; Chiesa, L.; Gourlay, S.A.; Hafalia, R.R.; Imbasciati, L.; Lietzke, A.F.; Sabbi, G.; Scanlan, R.M.

    2003-01-01

    During a quench, significant temperatures can arise as a magnet's stored energy is dissipated in the normal zone. Temperature gradients during this process give rise to localized strains within the coil. Reactive forces in the magnet structure balance the electromagnetic and thermal forces and maintain on equilibrium. In this paper we present a complete 3D finite element analysis of a racetrack coil. Specifically, the analysis focuses on thermal, electrical and mechanical conditions in a 10 T Nb 3 Sn coil built and tested as part of LBNL's Subscale Magnet Program. The study attempts to simulate time history of the temperature and voltage rise during quench propagation. The transient thermal stress after the quench is then evaluated and discussed

  2. Structural design of the superconducting toroidal field coils for ITER

    International Nuclear Information System (INIS)

    Wong, F.M.G.; Sborchia, C.; Thome, R.J.; Malkov, A.; Titus, P.H.

    1995-01-01

    Structural design issues and features of the superconducting toroidal field (TF) coils for the International Thermonuclear Experimental Reactor (ITER) will be discussed. Selected analyses of the structural and mechanical behavior of the ITER TF coils will also be presented. (orig.)

  3. Hybrid equilibrium field coils for the ORNL TNS

    International Nuclear Information System (INIS)

    Peng, Y.K.M.; Strickler, D.J; Dory, R.A.

    1977-01-01

    In this study, we make a comparative study of the power supplies required by interior and exterior [to the toroidal field (TF) coils] equilibrium field coils that are separately appropriate for high-β, D-shaped plasmas in TNS. It is shown that the interior coils need power supplies that are an order of magnitude below those required by the exterior coils (while the latter case is much less difficult to build than the former). A hybrid EF coil concept is proposed that combines the interior and the exterior coils to retain their advantages in avoiding large interior coils while lowering the power supplied to the exterior coils by an order of magnitude

  4. Testing of the European LCT coil in the TOSKA facility

    International Nuclear Information System (INIS)

    Herz, W.; Katheder, H.; Krauth, H.

    1985-01-01

    The EURATOM-LCT coil was tested as a single coil in TOSKA. Load cells were mounted in the support structure to monitor forces between coil and vacuum vessel during cooldown and coil charging. Disturbances of components by magnetic fringing fields were carefully considered. To investigate the mechanical behaviour and compare it with FEM-calculations the coil was equipped with strain gauge rosettes and displacement transducers. Van Mises stresses in the coil case are in agreement with calculations. As known from special investigations during coil manufacturing the average radial Young modulus varies along the periphery caused by the different curvatures. This leads to differences with FEM-calculation (larger gaps between winding and coil case) assuming a larger constant Young modulus performed at the beginning of the project

  5. Mechanical design of a high field common coil magnet

    CERN Document Server

    Caspi, S; Dietderich, D R; Gourlay, S A; Gupta, R; McInturff, A; Millos, G; Scanlan, R M

    1999-01-01

    A common coil design for high field 2-in-1 accelerator magnets has been previously presented as a "conductor-friendly" option for high field magnets applicable for a Very Large Hadron Collider. This paper presents the mechanical design for a 14 tesla 2-in-1 dipole based on the common coil design approach. The magnet will use a high current density Nb/sub 3/Sn conductor. The design addresses mechanical issues particular to the common coil geometry: horizontal support against coil edges, vertical preload on coil faces, end loading and support, and coil stresses and strains. The magnet is the second in a series of racetrack coil magnets that will provide experimental verification of the common coil design approach. (9 refs).

  6. Testing electrical insulation of LCT coils and instrumentation

    International Nuclear Information System (INIS)

    Luton, J.N.; Ulbricht, A.R.; Ellis, J.F.; Shen, S.S.; Wilson, C.T.; Okuno, K.; Siewerdt, L.O.; Zahn, G.R.; Zichy, J.A.

    1986-09-01

    Three of the superconducting test coils in the Large Coil Task (LCT) use conductors cooled internally by forced flow of helium. In the other three coils, the conductors are cooled externally by a bath of helium. The coils and facility are designed for rapid discharges (dumps) at voltages up to 2.5 kV, depending on coil design. Many coil sensors are connected electrically to the conductors. These sensor leads and signal conditioning equipment also experience high voltage. High-potential tests of ground insulation were performed on all components of the International Fusion Superconducting Magnet Test Facility (IFSMTF). Coil insulation was also tested by ring-down tests that produced voltage distributions within the coils like those occurring during rapid discharge. Methods were developed to localize problem areas and to eliminate them. The effect on breakdown voltage near the Paschen minimum of magnetic fields up to 2 T was investigated

  7. System Safety Assessment Based on Past Incidents in Oil and Gas Industries: A Focused Approach in Forecasting of Minor, Severe, Critical, and Catastrophic Incidents, 2010–2015

    Directory of Open Access Journals (Sweden)

    Praveen Patel

    2016-01-01

    Full Text Available Accident in an occupation which occurred due to series of repetitive minor incidents within the working environment. This work demonstrates the critical system safety assessment based on various incidents that took place to the different system and subsystem of two Indian oil refineries in five years of span 2010 to 2015. The categorization of incidents and hazard rate function of each incident category were classified and calculated. The result of Weibull analysis estimators in the form of scale and shape parameters provides useful information of incidents forecasting and their patterns in a particular time.

  8. High-resolution MR imaging of triangular fibrocartilage complex (TFCC): comparison of microscopy coils and a conventional small surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Yoshioka, Hiroshi [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Department of Radiology, Brigham and Women' s Hospital, 75 Francis Street, 02115, Boston, MA (United States); Ueno, Teruko; Itai, Yuji [Department of Radiology, University of Tsukuba, Tsukuba (Japan); Tanaka, Toshikazu [Department of Orthopedic Surgery, Tsukuba Kinen Hospital, Tsukuba (Japan); Shindo, Masashi [Tsukuba University Hospital, Tsukuba (Japan)

    2003-10-01

    To compare MR images of the triangular fibrocartilage complex (TFCC) using microscopy coils with those using a conventional surface coil qualitatively and quantitatively. Proton density-weighted images and T2*-weighted images of the TFCC from ten normal volunteers were obtained with a conventional surface coil (C4 coil; 80 mm in diameter), a 47-mm microscopy surface coil and a 23-mm microscopy surface coil at 1.5 T. Qualitative image analysis of MR images with three coils was performed by two radiologists who assigned one of five numerical scores (0, nonvisualization; 1, poor; 2, average; 3, good; 4, excellent) for five TFCC components, which were disc proper, triangular ligament, meniscus homologue, ulnotriquetral and ulnolunate ligament. Quantitative analysis included the signal-to-noise ratio (S/N) of the disc proper of TFCC, the lunate cartilage, the lunate bone and the contrast-noise-ratio (C/N) between articular cartilage and disc proper or bone marrow were measured. All structures show higher scores qualitatively on MR with microscopy coils than those with a C4 coil, and the difference was significant with the exception of the ulnolunate ligament. MR with microscopy coils showed significantly higher S/N values than those with a conventional surface coil (P<0.05 to P<0.001). T2*-weighted images using microscopy coils showed significantly higher cartilage-disc proper C/N and cartilage-bone marrow C/N (P<0.01 to P<0.001). On proton density-weighted images, the C/N between cartilage and disc proper with two microscopy coils was significantly higher (P<0.01) than that with a conventional coil. High-resolution MR images of the normal wrist using microscopy coils were superior to those using a conventional surface coil qualitatively and quantitatively. High-resolution MR imaging with a microscopy coil would be a promising method to diagnose TFCC lesions. (orig.)

  9. EXPERIMENTAL INVESTIGATION OF THE CONVECTIVE HEAT TRANSFER IN A SPIRALLY COILED CORRUGATED TUBE WITH RADIANT HEATING

    Directory of Open Access Journals (Sweden)

    Milan Đorđević

    2017-12-01

    Full Text Available The Archimedean spiral coil made of a transversely corrugated tube was exposed to radiant heating in order to represent a heat absorber of the parabolic dish solar concentrator. The main advantage of the considered innovative design solution is a coupling effect of the two passive methods for heat transfer enhancement - coiling of the flow channel and changes in surface roughness. The curvature ratio of the spiral coil varies from 0.029 to 0.234, while water and a mixture of propylene glycol and water are used as heat transfer fluids. The unique focus of this study is on specific boundary conditions since the heat flux upon the tube external surfaces varies not only in the circumferential direction, but in the axial direction as well. Instrumentation of the laboratory model of the heat absorber mounted in the radiation field includes measurement of inlet fluid flow rate, pressure drop, inlet and outlet fluid temperature and 35 type K thermocouples welded to the coil surface. A thermal analysis of the experimentally obtained data implies taking into consideration the externally applied radiation field, convective and radiative heat losses, conduction through the tube wall and convection to the internal fluid. The experimental results have shown significant enhancement of the heat transfer rate compared to spirally coiled smooth tubes, up to 240% in the turbulent flow regime.

  10. Behavioral based safety approaches

    International Nuclear Information System (INIS)

    Maria Michael Raj, I.

    2009-01-01

    Approach towards the establishment of positive safety culture at Heavy Water Plant, Tuticorin includes the adoption of several important methodologies focused on human behavior and culminates with achievement of Total Safety Culture where Quality and Productivity are integrated with Safety

  11. GBNV encoded movement protein (NSm) remodels ER network via C-terminal coiled coil domain

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Pratibha; Savithri, H.S., E-mail: bchss@biochem.iisc.ernet.in

    2015-08-15

    Plant viruses exploit the host machinery for targeting the viral genome–movement protein complex to plasmodesmata (PD). The mechanism by which the non-structural protein m (NSm) of Groundnut bud necrosis virus (GBNV) is targeted to PD was investigated using Agrobacterium mediated transient expression of NSm and its fusion proteins in Nicotiana benthamiana. GFP:NSm formed punctuate structures that colocalized with mCherry:plasmodesmata localized protein 1a (PDLP 1a) confirming that GBNV NSm localizes to PD. Unlike in other movement proteins, the C-terminal coiled coil domain of GBNV NSm was shown to be involved in the localization of NSm to PD, as deletion of this domain resulted in the cytoplasmic localization of NSm. Treatment with Brefeldin A demonstrated the role of ER in targeting GFP NSm to PD. Furthermore, mCherry:NSm co-localized with ER–GFP (endoplasmic reticulum targeting peptide (HDEL peptide fused with GFP). Co-expression of NSm with ER–GFP showed that the ER-network was transformed into vesicles indicating that NSm interacts with ER and remodels it. Mutations in the conserved hydrophobic region of NSm (residues 130–138) did not abolish the formation of vesicles. Additionally, the conserved prolines at positions 140 and 142 were found to be essential for targeting the vesicles to the cell membrane. Further, systematic deletion of amino acid residues from N- and C-terminus demonstrated that N-terminal 203 amino acids are dispensable for the vesicle formation. On the other hand, the C-terminal coiled coil domain when expressed alone could also form vesicles. These results suggest that GBNV NSm remodels the ER network by forming vesicles via its interaction through the C-terminal coiled coil domain. Interestingly, NSm interacts with NP in vitro and coexpression of these two proteins in planta resulted in the relocalization of NP to PD and this relocalization was abolished when the N-terminal unfolded region of NSm was deleted. Thus, the NSm

  12. Trends in tungsten coil atomic spectrometry

    Science.gov (United States)

    Donati, George L.

    Renewed interest in electrothermal atomic spectrometric methods based on tungsten coil atomizers is a consequence of a world wide increasing demand for fast, inexpensive, sensitive, and portable analytical methods for trace analysis. In this work, tungsten coil atomic absorption spectrometry (WCAAS) and tungsten coil atomic emission spectrometry (WCAES) are used to determine several different metals and even a non-metal at low levels in different samples. Improvements in instrumentation and new strategies to reduce matrix effects and background signals are presented. Investigation of the main factors affecting both WCAAS and WCAES analytical signals points to the importance of a reducing, high temperature gas phase in the processes leading to atomic cloud generation. Some more refractory elements such as V and Ti were determined for the first time by double tungsten coil atomic emission spectrometry (DWCAES). The higher temperatures provided by two atomizers in DWCAES also allowed the detection of Ag, Cu and Sn emission signals for the first time. Simultaneous determination of several elements by WCAES in relatively complex sample matrices was possible after a simple acid extraction. The results show the potential of this method as an alternative to more traditional, expensive methods for fast, more effective analyses and applications in the field. The development of a new metallic atomization cell is also presented. Lower limits of detection in both WCAAS and WCAES determinations were obtained due to factors such as better control of background signal, smaller, more isothermal system, with atomic cloud concentration at the optical path for a longer period of time. Tungsten coil-based methods are especially well suited to applications requiring low sample volume, low cost, sensitivity and portability. Both WCAAS and WCAES have great commercial potential in fields as diverse as archeology and industrial quality control. They are simple, inexpensive, effective

  13. Superconductive magnet having shim coils and quench protection circuits

    International Nuclear Information System (INIS)

    Schwall, R.E.

    1987-01-01

    A superconductive magnet is described comprising: a first persistent current loop comprising a first superconductor and a main coil connected to the first superconductor, the main coil being operative in response to superconduction therein to generate a primary magnetic field; a second persistent current loop comprising a second superconductor and a shim coil connected thereto, the shim coil being operative in response to superconduction therein to generate a corrective field for correcting aberrations in a predetermined gradient in the primary magnetic field, the shim coil having fewer turns than the main coil and being inductively coupled therewith whereby small changes in the current in the main coil cause much greater changes in the current in the shim coil. The magnet is characterized by an improvement which consists of: a first heater connected across the second persistent loop in parallel with the shim coil, the first heater being normally inoperative to carry current while the shim coil and the second superconductor are superconducting, the first heater being operative in response to current therein to heat the shim coil to a resistive state; and protective circuit means comprising a second heater connected to the main coil for carrying current from the main coil upon quenching of the main coil, the second heater being disposed in thermal contact with the second superconductor to heat the second superconductor to a resistive state in response to the current from the main coil to thereby divert current in the second persistent loop through the second heater causing it to heat the shim coil to a resistive state and resistively dissipate energy therein

  14. Development of a helical-coil double wall tube steam generator for 4S reactor

    International Nuclear Information System (INIS)

    Kitajima, Yuko; Maruyama, Shigeki; Jimbo, Noboru; Hino, Takehisa; Sato, Katsuhiko

    2011-01-01

    The 4S, Super-Safe Small and Simple, is a small-sized sodium-cooled fast reactor. A fast reactor usually uses sodium as a coolant to transfer heat from core to turbine/generator system. The heat of the intermediate heat transport system and that of the water stream systems are exchanged by the steam generator (SG) tubes. If the tube failure occurs, a sodium/water reaction could be occurred. To prevent the reaction and enhance safety, a helical-coil-type double wall tube with wire mesh interlayer and continuous monitoring systems of tube failure are applied to the SG of the 4S. The development and general features of this type double wall tube were described in Ref. 1) and Ref. 2). Those paper summarized following results; The tubes studied in these references were straight type. To establish this SG, development of manufacturing method of helical-coil-type double wall tube and validation of the tube failure monitoring system are needed. In this study, three demonstration tests have been performed; welding test of the double wall tube to manufacture the tubes with 70-80m length, assembling test of the helical-coil tube, and confirmation test of the tube processing system using the fabricated helical-coil tubes. As a result, following technologies have been successfully established. (1) Development of the welding techniques for manufacturing of the helical-coil-type double wall tube with wire mesh interlayer. (2) The confirmation test for manufacturing the helical coil tube of the SG. (author)

  15. Imbuing medical professionalism in relation to safety: a study protocol for a mixed-methods intervention focused on trialling an embedded learning approach that centres on the use of a custom designed board game.

    Science.gov (United States)

    Ward, Marie; McAuliffe, Eilish; Ní Shé, Éidín; Duffy, Ann; Geary, Una; Cunningham, Una; Holland, Catherine; McDonald, Nick; Egan, Karen; Korpos, Christian

    2017-07-17

    Healthcare organisations have a responsibility for ensuring that the governance of workplace settings creates a culture that supports good professional practice. Encouraging such a culture needs to start from an understanding of the factors that make it difficult for health professionals to raise issues of concern in relation to patient safety. The focus of this study is to determine whether a customised education intervention, developed as part of the study, with interns and senior house officers (SHOs) can imbue a culture of medical professionalism in relation to patient safety and support junior doctors to raise issues of concern, while shaping a culture of responsiveness and learning. We will use quantitative and qualitative methods to collect data. The sample size will be approximately 200 interns and SHOs across the two hospital sites. Two surveys will be included with one measuring leadership inclusiveness and psychological safety and a second capturing information on safety concerns that participants may have witnessed in their places of work. The PlayDecide embedded learning intervention will be developed with key stakeholders. This will be trialled in the middle stage of data collection for both interns and SHOs. A detailed content analysis will be conducted on the surveys to assess any changes in reporting following the PlayDecide intervention. This will be compared with the incident reporting levels and the results of the preintervention and postintervention leadership inclusiveness and psychological safety survey. Statistical analysis will be conducted using SPSS. Differences will be considered statistically significant at pethics approval from University College Dublin (Ref. LS-15-19-Ward-McAuliffe: Imbuing Medical Professionalism in Relation to Safety). The study results will be disseminated through peer-reviewed publications. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No

  16. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

    Directory of Open Access Journals (Sweden)

    Nora Céspedes

    Full Text Available Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Plasmodium falciparum were identified in the P. vivax genome. The peptides identified in silico were chemically synthesized; circular dichroism studies indicated partial or high α-helical content. Antigenicity was evaluated using human sera samples from malaria-endemic areas of Colombia and Papua New Guinea. Eight of these fragments were selected and used to assess immunogenicity in BALB/c mice. ELISA assays indicated strong reactivity of serum samples from individuals residing in malaria-endemic regions and sera of immunized mice, with the α-helical coiled coil structures. In addition, ex vivo production of IFN-γ by murine mononuclear cells confirmed the immunogenicity of these structures and the presence of T-cell epitopes in the peptide sequences. Moreover, sera of mice immunized with four of the eight antigens recognized native proteins on blood-stage P. vivax parasites, and antigenic cross-reactivity with three of the peptides was observed when reacted with both the P. falciparum orthologous fragments and whole parasites. Results here point to the α-helical coiled coil peptides as possible P. vivax malaria vaccine candidates as were observed for P. falciparum. Fragments selected here warrant further study in humans and non-human primate models to assess their protective efficacy as single components or assembled as hybrid linear epitopes.

  17. Coiled-coil forming peptides for the induction of silver nanoparticles

    International Nuclear Information System (INIS)

    Božič Abram, Sabina; Aupič, Jana; Dražić, Goran; Gradišar, Helena; Jerala, Roman

    2016-01-01

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  18. CCBuilder 2.0: Powerful and accessible coiled-coil modeling.

    Science.gov (United States)

    Wood, Christopher W; Woolfson, Derek N

    2018-01-01

    The increased availability of user-friendly and accessible computational tools for biomolecular modeling would expand the reach and application of biomolecular engineering and design. For protein modeling, one key challenge is to reduce the complexities of 3D protein folds to sets of parametric equations that nonetheless capture the salient features of these structures accurately. At present, this is possible for a subset of proteins, namely, repeat proteins. The α-helical coiled coil provides one such example, which represents ≈ 3-5% of all known protein-encoding regions of DNA. Coiled coils are bundles of α helices that can be described by a small set of structural parameters. Here we describe how this parametric description can be implemented in an easy-to-use web application, called CCBuilder 2.0, for modeling and optimizing both α-helical coiled coils and polyproline-based collagen triple helices. This has many applications from providing models to aid molecular replacement for X-ray crystallography, in silico model building and engineering of natural and designed protein assemblies, and through to the creation of completely de novo "dark matter" protein structures. CCBuilder 2.0 is available as a web-based application, the code for which is open-source and can be downloaded freely. http://coiledcoils.chm.bris.ac.uk/ccbuilder2. We have created CCBuilder 2.0, an easy to use web-based application that can model structures for a whole class of proteins, the α-helical coiled coil, which is estimated to account for 3-5% of all proteins in nature. CCBuilder 2.0 will be of use to a large number of protein scientists engaged in fundamental studies, such as protein structure determination, through to more-applied research including designing and engineering novel proteins that have potential applications in biotechnology. © 2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society.

  19. Coiled-coil forming peptides for the induction of silver nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Božič Abram, Sabina [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Graduate School of Biomedicine, University of Ljubljana, Ljubljana 1000 (Slovenia); Aupič, Jana [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Doctoral Programme in Chemical Sciences, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana 1000 (Slovenia); Dražić, Goran [Laboratory for Materials Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Gradišar, Helena [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia); Jerala, Roman, E-mail: roman.jerala@ki.si [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia)

    2016-04-08

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  20. Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert; Laga, Richard; Ulbrich, Karel; Bednárová, Lucie; Maloň, Petr; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Vaněk, O.

    2011-01-01

    Roč. 12, č. 10 (2011), s. 3645-3655 ISSN 1525-7797 R&D Projects: GA ČR GA203/08/0543; GA MŠk 1M0505 Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z40550506; CEZ:AV0Z50520514 Keywords : coiled coil * polymer the rapeutics * drug targeting Subject RIV: CC - Organic Chemistry Impact factor: 5.479, year: 2011

  1. Safety of Percutaneous Patent Ductus Arteriosus Closure: An Unselected Multicenter Population Experience

    Science.gov (United States)

    El‐Said, Howaida G.; Bratincsak, Andras; Foerster, Susan R.; Murphy, Joshua J.; Vincent, Julie; Holzer, Ralf; Porras, Diego; Moore, John; Bergersen, Lisa

    2013-01-01

    Background The technique and safety of transcatheter patent ductus arteriosus (PDA) closure have evolved during the past 20 years. We sought to report a multicenter experience of PDA closure with a focus on the rate of adverse events (AE) and a review of institutional practice differences. Methods and Results Outcome data on transcatheter PDA closure were collected at 8 centers prospectively using a multicenter registry (Congenital Cardiac Catheterization Project on Outcome Registry). Between February 2007 and June 2010, 496 PDA closures were recorded using a device in 338 (68%) or coils in 158 (32%). Most patients had an isolated PDA (90%). Fifty percent of patients were between 6 months and 3 years old, with only 40 patients (8%) closure and 1 mm (range 0.5 to 6 mm; IQR 1 to 2 mm) for coil closure (P2 mm (all P1.5 mm. In 9% of cases (n=46), an AE occurred; however, only 11 (2%) were classified as high severity. Younger age was associated with a higher AE rate. Coil‐related AEs were more common than device‐related AEs (10% versus 2%, Pclosure in the present era has a very low rate of complications, although these are higher in younger children. Technical intervention‐related events were more common in coil procedures compared with device procedures. For PDAs ≤2.5 mm in diameter, institutional differences in preference for device versus coil exist. PMID:24284214

  2. Transport of one SC coil through the village of Meyrin

    CERN Multimedia

    1956-01-01

    The energizing coils of the Synchro-cyclotron magnet were manufactured in Belgium before travelling to Basel in Switzerland by boat and continuing by road to Geneva. The first coil reached Geneva in December 1955, with the second following in early 1956. The coils were stored in a hangar at the Geneva airport before they were brought to CERN in May 1956.

  3. Strain and stress of the ASDEX multipole magnetic coils

    International Nuclear Information System (INIS)

    Jandl, O.; Pillsticker, M.

    1978-01-01

    A brief description of the technical concept of the multipole magnetic field coils for the ASDEX tokamak is given. The various loads of the coils are explained in quality. To compute displacement and stress of the coils FEM computer programs are used. The computing models applied to this problem are founded and the results and the conclusions are reported. (orig.) [de

  4. Mechanical study of 20 MJ superconducting pulse coil

    International Nuclear Information System (INIS)

    Hattori, Yasuhide; Shimamoto, Susumu

    1985-09-01

    This paper describes calculation methods and computer codes of stress distribution in a circular-shaped superconducting pulsed coils. The stress problems of a large sized superconducting coil, for example, are discussed for 20 MJ pool-cooled pulse coil. Young's modulus of a stranded flat cable, low rigidity, is measured and evaluated. (author)

  5. Effects of Gradient Coil Noise and Gradient Coil Replacement on the Reproducibility of Resting State Networks.

    Science.gov (United States)

    Bagarinao, Epifanio; Tsuzuki, Erina; Yoshida, Yukina; Ozawa, Yohei; Kuzuya, Maki; Otani, Takashi; Koyama, Shuji; Isoda, Haruo; Watanabe, Hirohisa; Maesawa, Satoshi; Naganawa, Shinji; Sobue, Gen

    2018-01-01

    The stability of the MRI scanner throughout a given study is critical in minimizing hardware-induced variability in the acquired imaging data set. However, MRI scanners do malfunction at times, which could generate image artifacts and would require the replacement of a major component such as its gradient coil. In this article, we examined the effect of low intensity, randomly occurring hardware-related noise due to a faulty gradient coil on brain morphometric measures derived from T1-weighted images and resting state networks (RSNs) constructed from resting state functional MRI. We also introduced a method to detect and minimize the effect of the noise associated with a faulty gradient coil. Finally, we assessed the reproducibility of these morphometric measures and RSNs before and after gradient coil replacement. Our results showed that gradient coil noise, even at relatively low intensities, could introduce a large number of voxels exhibiting spurious significant connectivity changes in several RSNs. However, censoring the affected volumes during the analysis could minimize, if not completely eliminate, these spurious connectivity changes and could lead to reproducible RSNs even after gradient coil replacement.

  6. Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils.

    Science.gov (United States)

    Steinkruger, Jay D; Bartlett, Gail J; Woolfson, Derek N; Gellman, Samuel H

    2012-09-26

    Pairing preferences in heterodimeric coiled coils are determined by complementarities among side chains that pack against one another at the helix-helix interface. However, relationships between dimer stability and interfacial residue identity are not fully understood. In the context of the "knobs-into-holes" (KIH) packing pattern, one can identify two classes of interactions between side chains from different helices: "lateral", in which a line connecting the adjacent side chains is perpendicular to the helix axes, and "vertical", in which the connecting line is parallel to the helix axes. We have previously analyzed vertical interactions in antiparallel coiled coils and found that one type of triad constellation (a'-a-a') exerts a strong effect on pairing preferences, while the other type of triad (d'-d-d') has relatively little impact on pairing tendencies. Here, we ask whether vertical interactions (d'-a-d') influence pairing in parallel coiled-coil dimers. Our results indicate that vertical interactions can exert a substantial impact on pairing specificity, and that the influence of the d'-a-d' triad depends on the lateral a' contact within the local KIH motif. Structure-informed bioinformatic analyses of protein sequences reveal trends consistent with the thermodynamic data derived from our experimental model system in suggesting that heterotriads involving Leu and Ile are preferred over homotriads involving Leu and Ile.

  7. Historical review: another 50th anniversary--new periodicities in coiled coils.

    Science.gov (United States)

    Gruber, Markus; Lupas, Andrei N

    2003-12-01

    In 1953, Francis Crick and Linus Pauling both proposed models of supercoiled alpha helices ('coiled coils') for the structure of keratin. These were the first attempts at modelling the tertiary structure of a protein. Crick emphasized the packing mode of the side-chains ('knobs-into-holes'), which required a periodicity of seven residues over two helical turns (7/2) and a supercoil in the opposite sense of the constituent helices. By contrast, Pauling envisaged a broader set of periodicities (4/1, 7/2, 18/5, 15/4, 11/3) and supercoils of both senses. Crick's model became canonical and the 'heptad repeat' essentially synonymous with coiled coils, but 50 years later new crystal structures and protein sequences show that the less common periodicities envisaged by Pauling also occur in coiled coils, adding a variant packing mode ('knobs-to-knobs') to the standard model. Pauling's laboratory notebooks suggest that he searched unsuccessfully for this packing mode in 1953.

  8. Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

    Science.gov (United States)

    Kuhn, Michael; Hyman, Anthony A.; Beyer, Andreas

    2014-01-01

    Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its functional repertoire through the course of evolution. We developed a refined sequence alignment technique that is more sensitive to coiled coil proteins, which are abundant in the centrosome. For proteins with high coiled-coil content, our algorithm identified 17% more reciprocal best hits than BLAST. Analyzing 108 eukaryotic genomes, we traced the evolutionary history of centrosome proteins. In order to assess how these proteins formed the centrosome and adopted new functions, we computationally emulated evolution by iteratively removing the most recently evolved proteins from the centrosomal protein interaction network. Coiled-coil proteins that first appeared in the animal–fungi ancestor act as scaffolds and recruit ancestral eukaryotic proteins such as kinases and phosphatases to the centrosome. This process created a signaling hub that is crucial for multicellular development. Our results demonstrate how ancient proteins can be co-opted to different cellular localizations, thereby becoming involved in novel functions. PMID:24901223

  9. Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study.

    Science.gov (United States)

    Park, Jeong Bae; Shin, Joon-Han; Kim, Dong-Soo; Youn, Ho-Joong; Park, Seung Woo; Shim, Wan Joo; Park, Chang Gyu; Kim, Dong-Woon; Lee, Hae-Young; Choi, Dong-Ju; Rim, Se-Joong; Lee, Sung-Yun; Kim, Ju-Han

    2016-04-01

    Doubling the dose of antihypertensive drugs is necessary to manage hypertension in patients whose disease is uncontrolled. However, this strategy can result in safety issues. This study compared the safety and efficacy of up-titration of the nifedipine gastrointestinal therapeutic system (GITS) with up-titration of valsartan monotherapy; these were also compared with low-dose combinations of the two therapies. This prospective, open-label, randomized, active-controlled, multicenter study lasted 8 weeks. If patients did not meet the target blood pressure (BP) after 4 weeks of treatment with low-dose monotherapy, they were randomized to up-titration of the nifedipine GITS dose from 30 mg (N30) to 60 mg or valsartan from 80 mg to 160 mg or they were randomized to receive a low-dose combination of N30 and valsartan 80 mg for another 4 weeks. BP variability was assessed by using the SD or the %CV of the short-term BP measured at clinic. Of the 391 patients (20~70 years with stage II or higher hypertension) screened for study inclusion, 362 patients who had 3 BP measurements were enrolled. The reduction in the mean systolic/diastolic BP from baseline to week 4 was similar in both low-dose monotherapy groups with either N30 or valsartan 80 mg. BP variability (SD) was unchanged with either therapy, but the %CV was slightly increased in the N30 group. There was no significant difference in BP variability either in SD or %CV between responders and nonresponders to each monotherapy despite the significant difference in the mean BP changes. The up-titration effect of nifedipine GTS from 30 to 60 mg exhibited an additional BP reduction, but this effect was not shown in the up-titration of valsartan from 80 to 160 mg. Although the difference in BP was obvious between high-dose nifedipine GTS and valsartan, the BP variability was unchanged between the 2 drugs and was similar to the low-dose combinations. There was a low rate of adverse events in all treatment groups. In addition

  10. Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging.

    Science.gov (United States)

    O'Reilly, Meaghan Anne; Jones, Ryan Matthew; Barrett, Edward; Schwab, Anthony; Head, Elizabeth; Hynynen, Kullervo

    2017-01-01

    Rationale: Ultrasound-mediated opening of the Blood-Brain Barrier(BBB) has shown exciting potential for the treatment of Alzheimer's disease(AD). Studies in transgenic mouse models have shown that this approach can reduce plaque pathology and improve spatial memory. Before clinical translation can occur the safety of the method needs to be tested in a larger brain that allows lower frequencies be used to treat larger tissue volumes, simulating clinical situations. Here we investigate the safety of opening the BBB in half of the brain in a large aged animal model with naturally occurring amyloid deposits. Methods: Aged dogs naturally accumulate plaques and show associated cognitive declines. Low-frequency ultrasound was used to open the BBB unilaterally in aged beagles (9-11yrs, n=10) in accordance with institutionally approved protocols. Animals received either a single treatment or four weekly treatments. Magnetic resonance imaging(MRI) was used to guide the treatments and assess the tissue effects. The animals underwent neurological testing during treatment follow-up, and a follow-up MRI exam 1 week following the final treatment. Results: The permeability of the BBB was successfully increased in all animals (mean enhancement: 19±11% relative to untreated hemisphere). There was a single adverse event in the chronic treatment group that resolved within 24 hrs. Follow-up MRI showed the BBB to be intact with no evidence of tissue damage in all animals. Histological analysis showed comparable levels of microhemorrhage between the treated and control hemispheres in the prefrontal cortex (single/repeat treatment: 1.0±1.4 vs 0.4±0.5/5.2±1.8 vs. 4.0±2.0). No significant differences were observed in beta-amyloid load (single/repeat: p=0.31/p=0.98) although 3/5 animals in each group showed lower Aβ loads in the treated hemisphere. Conclusion: Whole-hemisphere opening of the BBB was well tolerated in the aged large animal brain. The treatment volumes and frequencies

  11. Modeling of coupling mechanism of wireless power transfer system and vibration phenomenon of receiver-coil in three-coil system

    Directory of Open Access Journals (Sweden)

    Suqi Liu

    2017-11-01

    Full Text Available Wireless power transfer (WPT via coupled magnetic resonances has become a focus recently, but the mechanisms responsible for such work are uncertain. We found that WPT system is a self-organization system by utilizing self-organization theory to judge. Firstly, the circuit model was established and transfer characteristic of a system was researched by utilizing circuit theories. Thus, with the introduction of entropy variable S, the energy equation of state can be established from the energy of the transmitter side and the energy of the receiver side. According to the energy equation of state, this paper obtains two equations when the reactance of the transmitter side and the receiver side equate to zero respectively. The vibration phenomenon of the receiver-coil in a three-coil WPT system was predicted and explained. Our findings illuminate the unusual self-organization in the WPT system and explain the vibration phenomenon of the receiver-coil in a three-coil WPT system.

  12. Modeling of coupling mechanism of wireless power transfer system and vibration phenomenon of receiver-coil in three-coil system

    Science.gov (United States)

    Liu, Suqi; Tan, Jianping; Wen, Xue

    2017-11-01

    Wireless power transfer (WPT) via coupled magnetic resonances has become a focus recently, but the mechanisms responsible for such work are uncertain. We found that WPT system is a self-organization system by utilizing self-organization theory to judge. Firstly, the circuit model was established and transfer characteristic of a system was researched by utilizing circuit theories. Thus, with the introduction of entropy variable S, the energy equation of state can be established from the energy of the transmitter side and the energy of the receiver side. According to the energy equation of state, this paper obtains two equations when the reactance of the transmitter side and the receiver side equate to zero respectively. The vibration phenomenon of the receiver-coil in a three-coil WPT system was predicted and explained. Our findings illuminate the unusual self-organization in the WPT system and explain the vibration phenomenon of the receiver-coil in a three-coil WPT system.

  13. An 8-channel transceiver 7-channel receive RF coil setup for high SNR ultrahigh-field MRI of the shoulder at 7T.

    Science.gov (United States)

    Rietsch, Stefan H G; Pfaffenrot, Viktor; Bitz, Andreas K; Orzada, Stephan; Brunheim, Sascha; Lazik-Palm, Andrea; Theysohn, Jens M; Ladd, Mark E; Quick, Harald H; Kraff, Oliver

    2017-12-01

    In this work, we present an 8-channel transceiver (Tx/Rx) 7-channel receive (Rx) radiofrequency (RF) coil setup for 7 T ultrahigh-field MR imaging of the shoulder. A C-shaped 8-channel Tx/Rx coil was combined with an anatomically close-fitting 7-channel Rx-only coil. The safety and performance parameters of this coil setup were evaluated on the bench and in phantom experiments. The 7 T MR imaging performance of the shoulder RF coil setup was evaluated in in vivo measurements using a 3D DESS, a 2D PD-weighted TSE sequence, and safety supervision based on virtual observation points. Distinct SNR gain and acceleration capabilities provided by the additional 7-channel Rx-only coil were demonstrated in phantom and in vivo measurements. The power efficiency indicated good performance of each channel and a maximum B 1 + of 19 μT if the hardware RF power limits of the MR system were exploited. MR imaging of the shoulder was demonstrated with clinically excellent image quality and submillimeter spatial resolution. The presented 8-channel transceiver 7-channel receive RF coil setup was successfully applied for in vivo 7 T MRI of the shoulder providing a clear SNR gain vs the transceiver array without the additional receive array. Homogeneous images across the shoulder region were obtained using 8-channel subject-specific phase-only RF shimming. © 2017 American Association of Physicists in Medicine.

  14. Tolerance Evaluation of Poloidal Shear Keys for ITER TF Coil

    International Nuclear Information System (INIS)

    Fu Youkun; Neil, M.; Cees Jong

    2006-01-01

    There are 18 ITER Toroidal Field (TF) Coils. Unlike the other ITER coils, these coils are structurally linked. These links consist of friction between the coil legs in the central vault formed by the inner straight legs of the coils, four outer inter-coil structures (OIS) and one inner inter-coil structure (IIS). The OIS consists essentially of bands around all 18 coils to provide shear support by forming shear panels with the coil case, and the IIS consists of poloidal circular keys placed directly between the coil cases. Global analysis of the 'perfect' coil shape has shown high stresses in the IIS, in the poloidal keyways. Optimization has successfully reduced these stresses to acceptable values as regards the expected fatigue resistance. However it is necessary to confirm that the stresses are still acceptable when realistic values of geometry variations are included (i.e. the effect of coil and case tolerances). Because of the extensive mechanical links between coils the poloidal key stresses can also be affected by tolerances elsewhere in the case. As the first step in assessment of the possible variations in stresses, a substructure technique is being used to develop a local model of the key region. The result of geometry variations between individual coils is a loss in the 18 fold symmetry used to simplify previous analyses. With the new and optimized model it should be possible to relax the 18-fold symmetry, but a full analysis of all 18 coils is still not possible. Systematic ways of representing the tolerance variation in the finite element model have been developed so that parametric studies can be undertaken without a full reconstruction of the model. (author)

  15. Exploring the conserved water site and hydration of a coiled-coil trimerisation motif: a MD simulation study.

    Science.gov (United States)

    Dolenc, Jozica; Baron, Riccardo; Missimer, John H; Steinmetz, Michel O; van Gunsteren, Wilfred F

    2008-07-21

    The solvent structure and dynamics around ccbeta-p, a 17-residue peptide that forms a parallel three-stranded alpha-helical coiled coil in solution, was analysed through 10 ns explicit solvent molecular dynamics (MD) simulations at 278 and 330 K. Comparison with two corresponding simulations of the monomeric form of ccbeta-p was used to investigate the changes of hydration upon coiled-coil formation. Pronounced peaks in the solvent density distribution between residues Arg8 and Glu13 of neighbouring helices show the presence of water bridges between the helices of the ccbeta-p trimer; this is in agreement with the water sites observed in X-ray crystallography experiments. Interestingly, this water site is structurally conserved in many three-stranded coiled coils and, together with the Arg and Glu residues, forms part of a motif that determines three-stranded coiled-coil formation. Our findings show that little direct correlation exists between the solvent density distribution and the temporal ordering of water around the trimeric coiled coil. The MD-calculated effective residence times of up to 40 ps show rapid exchange of surface water molecules with the bulk phase, and indicate that the solvent distribution around biomolecules requires interpretation in terms of continuous density distributions rather than in terms of discrete molecules of water. Together, our study contributes to understanding the principles of three-stranded coiled-coil formation.

  16. Unraveling double stranded alpha-helical coiled coils: an x-ray diffraction study on hard alpha-keratin fibers.

    Science.gov (United States)

    Kreplak, L; Doucet, J; Briki, F

    2001-04-15

    Transformations of proteins secondary and tertiary structures are generally studied in globular proteins in solution. In fibrous proteins, such as hard alpha-keratin, that contain long and well-defined double stranded alpha-helical coiled coil domains, such study can be directly done on the native fibrous tissue. In order to assess the structural behavior of the coiled coil domains under an axial mechanical stress, wide angle x-ray scattering and small angle x-ray scattering experiments have been carried out on stretched horse hair fibers at relative humidity around 30%. Our observations of the three major axial spacings as a function of the applied macroscopic strain have shown two rates. Up to 4% macroscopic strain the coiled coils were slightly distorted but retained their overall conformation. Above 4% the proportion of coiled coil domains progressively decreased. The main and new result of our study is the observation of the transition from alpha-helical coiled coils to disordered chains instead of the alpha-helical coiled coil to beta-sheet transition that occurs in wet fibers.

  17. Study on the performance improvement of the high temperature superconducting coil with several separated coils at the edges

    International Nuclear Information System (INIS)

    Ishiguri, S.; Oka, T.; Fukui, S.; Ogawa, J.; Sato, T.

    2008-01-01

    In designing high temperature superconducting (HTS) coils, it is important to secure large magnetic fields and stored energy using shorter tape length. Thus, it is necessary to improve the transport current performance of the coils. The critical current and n-value of an HTS tape depend on magnetic fields and flux angles under constant temperature. Considering these dependencies, we established a model to analyze coil critical current. This model clarifies that relatively large electric fields are generated at the coil edges. This adversely affects the transport current performance. In this study, the coil edge is separated into several coils, keeping the total tape length constant. This increases the coil critical current, stored energy, central magnetic field, and also the coil volume, which contains vacancies created by the separation. To estimate coil performance, we calculated the stored energy density, whose denominator is the increased coil volume. This stored energy density reaches its maximum value when the number of the separated coils is eight. At this optimum separation, the central magnetic field increases by 13%, and the stored energy improves by 43%, compared to a rectangular coil wound with the same tape length

  18. CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies.

    Science.gov (United States)

    Wood, Christopher W; Bruning, Marc; Ibarra, Amaurys Á; Bartlett, Gail J; Thomson, Andrew R; Sessions, Richard B; Brady, R Leo; Woolfson, Derek N

    2014-11-01

    The ability to accurately model protein structures at the atomistic level underpins efforts to understand protein folding, to engineer natural proteins predictably and to design proteins de novo. Homology-based methods are well established and produce impressive results. However, these are limited to structures presented by and resolved for natural proteins. Addressing this problem more widely and deriving truly ab initio models requires mathematical descriptions for protein folds; the means to decorate these with natural, engineered or de novo sequences; and methods to score the resulting models. We present CCBuilder, a web-based application that tackles the problem for a defined but large class of protein structure, the α-helical coiled coils. CCBuilder generates coiled-coil backbones, builds side chains onto these frameworks and provides a range of metrics to measure the quality of the models. Its straightforward graphical user interface provides broad functionality that allows users to build and assess models, in which helix geometry, coiled-coil architecture and topology and protein sequence can be varied rapidly. We demonstrate the utility of CCBuilder by assembling models for 653 coiled-coil structures from the PDB, which cover >96% of the known coiled-coil types, and by generating models for rarer and de novo coiled-coil structures. CCBuilder is freely available, without registration, at http://coiledcoils.chm.bris.ac.uk/app/cc_builder/. © The Author 2014. Published by Oxford University Press.

  19. Focusing ethnography

    DEFF Research Database (Denmark)

    Woermann, Niklas

    2018-01-01

    underpinnings of focusing ethnographic research by comparing different schools of thought and suggesting a practice theory-based approach. It argues that many research projects are focused but do not reflect on the process of focusing, describes how to identify focal settings or practices, and introduces......Building theory with ethnography and filmic research increasingly requires focussing on key practices or settings, instead of painting a broad panorama of a culture. But few authors discuss why and how to focus. This article provides a systematic discussion of the theoretical and methodological...

  20. Physiological Studies on Pea Tendrils. IV. Flavonoids and Contact Coiling

    Science.gov (United States)

    Jaffe, M. J.; Galston, A. W.

    1967-01-01

    Pea tendrils contain high concentrations of flavonoids, mainly quercetin-triglucosyl-p-coumarate (QGC). QGC is most abundant near the highly responsive apex of the tendril, and least abundant at the base. After mechanical stimulation, and during coiling of the tendril, the QGC titer drops to about 30% of its original value. The kinetics of flavonoid disappearance are significantly correlated with the kinetics of coiling. Aqueous extracts of unstimulated pea tendrils or 10 μm QGC inhibit contact coiling of excised tendrils. Extracts of coiled tendrils do not. The evidence indicates a possible regulatory role for flavonoids in contact coiling. PMID:16656581

  1. Superconducting coil system and methods of assembling the same

    Science.gov (United States)

    Rajput-Ghoshal, Renuka; Rochford, James H.; Ghoshal, Probir K.

    2016-01-19

    A superconducting magnet apparatus is provided. The superconducting magnet apparatus includes a power source configured to generate a current; a first switch coupled in parallel to the power source; a second switch coupled in series to the power source; a coil coupled in parallel to the first switch and the second switch; and a passive quench protection device coupled to the coil and configured to by-pass the current around the coil and to decouple the coil from the power source when the coil experiences a quench.

  2. The IEA large coil task test results in IFSMTF

    International Nuclear Information System (INIS)

    Lubell, M.S.; Clinard, J.A.; Dresner, L.

    1987-01-01

    The Large Coil Task (LCT) is an international collaboration of the United States, EURATOM, Japan, and Switzerland to develop large superconducting magnets for fusion reactors. The testing phase of LCT was completed on September 3, 1987. All six coils exceeded the design goals, both as single coils and in six-coil toroidal tests. In addition, a symmetric torus test was performed in which a maximum field of 9 T was reached in all coils simultaneously. These are by far the largest magnets (either in size, weight, or stored energy) ever to achieve such a field. 6 refs., 6 figs., 3 tabs

  3. Random coil chemical shift for intrinsically disordered proteins

    DEFF Research Database (Denmark)

    Kjærgaard, Magnus; Brander, Søren; Poulsen, Flemming Martin

    2011-01-01

    . Temperature has a non-negligible effect on the (13)C random coil chemical shifts, so temperature coefficients are reported for the random coil chemical shifts to allow extrapolation to other temperatures. The pH dependence of the histidine random coil chemical shifts is investigated in a titration series......, which allows the accurate random coil chemical shifts to be obtained at any pH. By correcting the random coil chemical shifts for the effects of temperature and pH, systematic biases of the secondary chemical shifts are minimized, which will improve the reliability of detection of transient secondary...

  4. SSC [Superconducting Super Collider] dipole coil production tooling

    International Nuclear Information System (INIS)

    Carson, J.A.; Barczak, E.J.; Bossert, R.C.; Brandt, J.S.; Smith, G.A.

    1989-03-01

    Superconducting Super Collider dipole coils must be produced to high precision to ensure uniform prestress and even conductor distribution within the collared coil assembly. Tooling is being prepared at Fermilab for the production of high precision 1M and 16.6M SSC dipole coils suitable for mass production. The design and construction methods builds on the Tevatron tooling and production experience. Details of the design and construction methods and measured coil uniformity of 1M coils will be presented. 4 refs., 10 figs

  5. Tight aspect ratio tokamak power reactor with superconducting TF coils

    International Nuclear Information System (INIS)

    Nishio, S.; Tobita, K.; Konishi, S.; Ando, T.; Hiroki, S.; Kuroda, T.; Yamauchi, M.; Azumi, M.; Nagata, M.

    2003-01-01

    Tight aspect ratio tokamak power reactor with super-conducting toroidal field (TF) coils has been proposed. A center solenoid coil system and an inboard blanket were discarded. The key point was how to find the engineering design solution of the TF coil system with the high field and high current density. The coil system with the center post radius of less than 1 m can generate the maximum field of ∼ 20 T. This coil system causes a compact reactor concept, where the plasma major and minor radii of 3.75 m and 1.9 m, respectively and the fusion power of 1.8 GW. (author)

  6. Instrumentation and test of the Swiss LCT-coil

    International Nuclear Information System (INIS)

    Zichy, J.A.; Horvath, I.; Jakob, B.; Marinucci, C.; Vecsey, G.; Weymuth, P.; Zellweger, J.

    1985-01-01

    Just before Christmas 1983 the fabrication of the Swiss LCT-coil was finished. Tests at ambient temperature were performed on the factory site and after delivery in Oak Ridge. To avoid an undesirable delay of the rescheduled Partial-Array Test it was agreed to install the coil without its superconducting bus. In July 1984 the Swiss LCT-coil was successfully cooled down to LHe temperature together with the other two fully installed coils. Besides the cooling system, the instrumentation, measured parameters of the coil and some preliminary results obtained during the ongoing Partial-Array Test are presented

  7. Assessment of the microbiological safety of edible dried seeds from retail premises in the United Kingdom with a focus on Salmonella spp.

    Science.gov (United States)

    Willis, Caroline; Little, Christine L; Sagoo, Satnam; de Pinna, Elizabeth; Threlfall, John

    2009-12-01

    Sesame seed products have recently been associated with a number of Salmonella outbreaks in the UK and elsewhere. Aside from sesame seeds, there is little published information on the prevalence of Salmonella spp. in edible seeds. A study of 3735 samples of retail edible dried seeds in the UK was therefore carried out between October 2007 and March 2008 to assess their microbiological safety in relation to Salmonella contamination and levels of Escherichia coli, an indicator of faecal contamination. Overall, Salmonella was detected in 23 samples (0.6%), of which over half (57%) were sesame seeds. Other seeds contaminated with Salmonella were linseed (1 sample), sunflower (1 sample), alfalfa (1 sample), melon (4 samples) and mixed seeds (3 samples). E. coli was detected in 9% of samples, with 1.5% containing unsatisfactory levels (> or = 10(2)/g). These included melon, pumpkin, sesame, hemp, poppy, linseed, sunflower and mixed seeds. The UK retailers affected by the detection of Salmonella in their products recalled the contaminated batches, and Food Standards Agency food alerts were issued to advise against the consumption of affected seed products. This study highlights the importance of good hygiene practices and effective decontamination procedures during the production of these products.

  8. Clinical observation on coil embolization in treatment of hepatic arterial pseudoaneurysm

    International Nuclear Information System (INIS)

    Chen Yaoting; Xu Linfeng; Jiang Rongjian; Zhou Jingxing; Luo Jianghong; Tang Qiyun; Hu Renmei

    2007-01-01

    Objective: To discuss the method, mid-long term clinical therapeutic effect and safety of coil embolization in treating patients with hepatic arterial pseudoaneurysm (HAPA). Methods: Seven patients with repeatedly massive hemorrhage of gastrointestinal tract were undertaken DSA of celiac arteries and hepatic arteries and embolization of the feeding artery by coils or microcoils after correct diagnosis. All cases underwent follow-up from 6 to 60 months(mean 38). Results: The blood loss before angiography was ranged from 1200 to 4 000 (mean 2 385) ml. There were 3 cases with normal hepatic function and 4 with hepatic dysfunction including ALT increase in 2 and obstructive jaundice in another. Digital substraction angiography (DSA) clearly showed the location, shape and feeding arteries of HAPA. There were 2 types of HAPA namely intrahepatic (n=3)and extrahepatic (n=4), adding one case with arteriovenous fistula (AVF). Embolization was successful in all cases by coils (n=13) or microcoils (n=12). No recurrence and any definite clinical complication occurred during follow-up. Conclusion: Coil embolization in treating HAPA is safe and effective with mid-long term positive clinical therapeutic efficiency without severe complications. (authors)

  9. Coil supporting device for a nuclear fusion device

    International Nuclear Information System (INIS)

    Kuno, Kazuo.

    1976-01-01

    Object: To reduce a thermal stress of a coil such as a magnetic limiter to minimize stress acting on a protective tube of the coil. Structure: A coil within a protective tube has its outer periphery surrounded and supported by a heat-resisting material such as ceramic at more than two positions suitably spaced lengthwise of a coil conductor, and heat insulating members are interposed between both sides of the coil and the protective tube so that it may be retained with respect to the width of the coil. Further, a heat-resisting resilient member is inserted in a clearance between an outer circumference and an inner circumference of the coil to allow a radial displacement of the coil. As a result, elongation of the coil due to thermal expansion may be escaped at the aforesaid two supports to reduce thermal stress of the coil and protective tube to support the coil within the protective tube in positively heat-resisting and insulating manner. (Kamimura, M.)

  10. Measurement of a Conduction Cooled Nb3Sn Racetrack Coil

    Science.gov (United States)

    Kim, HS; Kovacs, C.; Rochester, J.; Sumption, MD; Tomsic, M.; Peng, X.; Doll, D.

    2017-12-01

    Use of superconducting coils for wind turbines and electric aircraft is of interest because of the potential for high power density and weight reduction. Here we test a racetrack coil developed as a proof-of-concept for cryogen-free superconducting motors and generators. The coil was wound with 1209 m of 0.7-mm-diameter insulated tube-type Nb3Sn wire. The coil was epoxy-impregnated, instrumented, covered with numerous layers of aluminized mylar insulation, and inserted vertically into a dewar. The system was cooled to 4.2 K, and a few inches of liquid helium was allowed to collect at the bottom of the dewar but below the coil. The coil was cooled by conduction via copper cooling bars were attached to the coil but also were immersed in the liquid helium at their lower ends. Several current tests were performed on the coil, initially in voltage mode, and one run in current mode. The maximum coil Ic at 4.2 K was 480 A, generating 3.06 T at the surface of the coil. The coil met the design targets with a noticeable margin.

  11. Stress relaxation in SSC 50mm dipole coils

    International Nuclear Information System (INIS)

    Rogers, D.; Markley, F.

    1992-04-01

    We are measuring the stress relaxation of SSC 50mm outer coils with the goal of predicting how much of the coil prestress will be lost while the coils are warehoused between manufacture and cooldown. We manufacture 3 inch (76.2mm) long segments of coil with the same materials and techniques that have been used for prototype coils. We are running four simultaneous tests in an attempt to separate the contributions of the different coil materials. Test one is a completely insulated coil section where the insulation is the all polyamide system being tested at Brookhaven; test two is a wire stack insulated only with the normal Kapton overwrap; test three is a stack of bare cable; and test four is a completely insulated normal coil section. All, except for the bare cable, include the ground insulation. The insulated coil sections are carefully dried before loading and testing in order to eliminate stress changes due to varying moisture content. The temperature dependence of the stress relaxation is being studied separately. Three companion papers presented at this conference will be: (1) ''Temperature dependence of the viscoelastic properties of SSC coil insulation'' (2) ''Measurement of the elastic modulus of Kapton perpendicular to the plane of the film at room and cryogenic temperatures'' (3) ''Theoretical methods for creep and stress relaxation studies of SSC coil.''

  12. Eccentric figure-eight coils for transcranial magnetic stimulation.

    Science.gov (United States)

    Sekino, Masaki; Ohsaki, Hiroyuki; Takiyama, Yoshihiro; Yamamoto, Keita; Matsuzaki, Taiga; Yasumuro, Yoshihiro; Nishikawa, Atsushi; Maruo, Tomoyuki; Hosomi, Koichi; Saitoh, Youichi

    2015-01-01

    Previously we proposed an eccentric figure-eight coil that can cause threshold stimulation in the brain at lower driving currents. In this study, we performed numerical simulations and magnetic stimulations to healthy subjects for evaluating the advantages of the eccentric coil. The simulations were performed using a simplified spherical brain model and a realistic human brain model. We found that the eccentric coil required a driving current intensity of approximately 18% less than that required by the concentric coil to cause comparable eddy current densities within the brain. The eddy current localization of the eccentric coil was slightly higher than that of the concentric coil. A prototype eccentric coil was designed and fabricated. Instead of winding a wire around a bobbin, we cut eccentric-spiral slits on the insulator cases, and a wire was woven through the slits. The coils were used to deliver magnetic stimulation to healthy subjects; among our results, we found that the current slew rate corresponding to motor threshold values for the concentric and eccentric coils were 86 and 78 A/µs, respectively. The results indicate that the eccentric coil consistently requires a lower driving current to reach the motor threshold than the concentric coil. Future development of compact magnetic stimulators will enable the treatment of some intractable neurological diseases at home. © 2014 Wiley Periodicals, Inc.

  13. Coils in a fusion device and its fabrication method

    International Nuclear Information System (INIS)

    Maeda, Hideto; Moritani, Einoshin.

    1975-01-01

    Object: To provide a coil for nuclear fusion equipment, which coil has superior rigidity and strength and is separable into two sections and used for removing impurity ions from high temperature plasma such as heavy hydrogen and tritium. Structure: The coil according to the invention is manufactured by (1) a step of insulating horseshoe-shaped conductors one from another and bundling them into coil halves. (2) a step of assembling a flange on a coil case accommodating each coil half and hermetically welding a lid to each end of the coil half, (3) a step of evacuating the interior of each coil case, (4) a step of pouring a thermosetting resin into each evacuated coil case and hardening the resin, (5) a step of connecting the two coil halves with their ends not covered with resin held in abutting relation to each other, (6) a step of coupling coil case joint pieces to the joined portions and covering the joint pieces with a seal box and hermetically welding the box to the joint pieces, and (7) a step of pouring a thermosetting resin into each evacuated joint portion and hardening the resin. (Kamimura, M.)

  14. Performance of the Conduction-Cooled LDX Levitation Coil

    Science.gov (United States)

    Michael, P. C.; Schultz, J. H.; Smith, B. A.; Titus, P. H.; Radovinsky, A.; Zhukovsky, A.; Hwang, K. P.; Naumovich, G. J.; Camille, R. J.

    2004-06-01

    The Levitated Dipole Experiment (LDX) was developed to study plasma confinement in a dipole magnetic field. Plasma is confined in the magnetic field of a 680-kg Nb3Sn Floating Coil (F-coil) that is electromagnetically supported at the center of a 5-m diameter by 3-m tall vacuum chamber. The Levitation Coil (L-coil) is a 2800-turn, double pancake winding that supports the weight of the F-coil and controls its vertical position within the vacuum chamber. The use of high-temperature superconductor (HTS) Bi-2223 for the L-coil minimizes the electrical and cooling power needed for levitation. The L-coil winding pack and support plate are suspended within the L-coil cryostat and cooled by conduction to a single-stage cryocooler rated for 25-W heat load at approximately 20 K. The coil current leads consist of conduction-cooled copper running from room temperature to 80 K and a pair of commercially-available, 150-A HTS leads. An automatically filled liquid-nitrogen reservoir provides cooling for the coil's radiation shield and for the leads' 80-K heat stations. This paper discusses the L-coil system design and its observed cryogenic performance.

  15. Deep brain transcranial magnetic stimulation using variable "Halo coil" system

    Science.gov (United States)

    Meng, Y.; Hadimani, R. L.; Crowther, L. J.; Xu, Z.; Qu, J.; Jiles, D. C.

    2015-05-01

    Transcranial Magnetic Stimulation has the potential to treat various neurological disorders non-invasively and safely. The "Halo coil" configuration can stimulate deeper regions of the brain with lower surface to deep-brain field ratio compared to other coil configurations. The existing "Halo coil" configuration is fixed and is limited in varying the site of stimulation in the brain. We have developed a new system based on the current "Halo coil" design along with a graphical user interface system that enables the larger coil to rotate along the transverse plane. The new system can also enable vertical movement of larger coil. Thus, this adjustable "Halo coil" configuration can stimulate different regions of the brain by adjusting the position and orientation of the larger coil on the head. We have calculated magnetic and electric fields inside a MRI-derived heterogeneous head model for various positions and orientations of the coil. We have also investigated the mechanical and thermal stability of the adjustable "Halo coil" configuration for various positions and orientations of the coil to ensure safe operation of the system.

  16. 48{sup th} Annual meeting on nuclear technology (AMNT 2017). Key topic / Enhanced safety and operation excellence. Focus session: Uncertainty analyses in reactor core simulations

    Energy Technology Data Exchange (ETDEWEB)

    Zwermann, Winfried [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany). Forschungszentrum

    2017-12-15

    The supplementation of reactor simulations by uncertainty analyses is becoming increasingly important internationally due to the fact that the reliability of simulation calculations can be significantly increased by the quantification of uncertainties in comparison to the use of so-called conservative methods (BEPU- ''Best-Estimate plus Uncertainties''). While systematic uncertainty analyses for thermo-hydraulic calculations have been performed routinely for a long time, methods for taking into account uncertainties in nuclear data, which are the basis for neutron transport calculations, are under development. The Focus Session Uncertainty Analyses in Reactor Core Simulations was intended to provide an overview of international research and development with respect to supplementing reactor core simulations with uncertainty and sensitivity analyses, in research institutes as well as within the nuclear industry. The presented analyses not only focused on light water reactors, but also on advanced reactor systems. Particular emphasis was put on international benchmarks in the field. The session was chaired by Winfried Zwermann (Gesellschaft fuer Anlagen- und Reaktorsicherheit).

  17. The study of the effectiveness and safety of vitamin-mineral complex «Focus Forte» for myopia treatment

    Directory of Open Access Journals (Sweden)

    E. Yu. Egorova

    2012-01-01

    Full Text Available Purpose: the estimation of the results of a randomized study of the effectiveness of vitamin-mineral complex «Focus Forte» at myopia.Methods: this study included 60 young patients (in age from 16 to18 years, university students, full-time education in the context of complex treatment within 2 months. Patients were randomized to receive the preparation (n=30 or into the control group (standard therapy, n=30. On the day «0» and the day «60» over 80 parameters of vision were measured using a special software package.Results: the comparisons of the studied parameters of vision on the day of «60» shown statistically significant differences in electrosen- sibility (O. R. 4.6, 95% C. I. 1.4-16, p=0,03, spatial contrast sensitivity (O. R. 9.0, 95% C. I. 1.5-17, p<0,006 and luminance sensitivity (O. R. 5.6, 95% DI 1.7-19; p=0,003 as well as a significant reduction of clinical symptoms of zinc deficiency and hypovitaminosеs A, C, E, B2 (p<0,001.Conclusion: «Focus Forte» helps to improve visual function among the students with myopia, helping to compensate for deficiency of vitamins and micronutrients, which is required for the physiological support of the molecular processes of vision.

  18. The study of the effectiveness and safety of vitamin-mineral complex «Focus Forte» for myopia treatment

    Directory of Open Access Journals (Sweden)

    E. Yu. Egorova

    2014-07-01

    Full Text Available Purpose: the estimation of the results of a randomized study of the effectiveness of vitamin-mineral complex «Focus Forte» at myopia.Methods: this study included 60 young patients (in age from 16 to18 years, university students, full-time education in the context of complex treatment within 2 months. Patients were randomized to receive the preparation (n=30 or into the control group (standard therapy, n=30. On the day «0» and the day «60» over 80 parameters of vision were measured using a special software package.Results: the comparisons of the studied parameters of vision on the day of «60» shown statistically significant differences in electrosen- sibility (O. R. 4.6, 95% C. I. 1.4-16, p=0,03, spatial contrast sensitivity (O. R. 9.0, 95% C. I. 1.5-17, p<0,006 and luminance sensitivity (O. R. 5.6, 95% DI 1.7-19; p=0,003 as well as a significant reduction of clinical symptoms of zinc deficiency and hypovitaminosеs A, C, E, B2 (p<0,001.Conclusion: «Focus Forte» helps to improve visual function among the students with myopia, helping to compensate for deficiency of vitamins and micronutrients, which is required for the physiological support of the molecular processes of vision.

  19. Coil irrigation in sugar cane (Saccharum officinarum

    Directory of Open Access Journals (Sweden)

    Jesús Sánchez Gutiérrez

    2016-01-01

    Full Text Available This study was made at the Basic Seed Bank of the Local Sugar Cane Research Station for the Mideastern Cuba, based in Camaguey, on brown carbonate soil, between 2013 and 12014. Coil irrigation was applied to meet the water requirements for the crop, according to the edafoclimatic conditions and the different phenological phases it has. The Savo method was used to determine useful rain water. Adjustment and complementation of the irrigation program was based on indicators that characterize the exploitation scheme. The machine´s working parameters were determined to meet the water needs, and increase crop´s overall yields. The evaluations and results achieved have contributed to new proposals for management and operation of coil irrigation, and they are important to increase its efficiency.

  20. Superconductors for W VII-X coils

    International Nuclear Information System (INIS)

    Maurer, W.

    1987-01-01

    Superconductor concepts are discussed with respect to operational current, cooling and bending behavior, and ac losses. The encouraging results for NbTi superconducting technology are recalled. It is argued that the WVII-X stellarator modular superconducting coils can be built just as the modular Cu coils for WVII-AS. Special attention must be paid to the dB/dt allowed for the conductor. Shape and price depend on the means used to avoid ac losses. Formula to elucidate the main physical parameters influencing ac loss behavior of superconductors are given. Configurations investigated with respect to plasma behavior are compared. Masses to be cooled were estimated for two configurations. The estimated cooling power is of the order of 3kW

  1. Power conditioner for a coil-gun

    International Nuclear Information System (INIS)

    Zabar, Z.; Joshi, P.N.

    1987-01-01

    This paper describes a power conditioning scheme for introducing currents sequentially into a linear array of coils which form the barrel of a coil-gun. The projectile, a conducting cylindrical sleeve, is driven by the force exerted on it by a traveling magnetic wave-packet created by the barrel currents. Since the rate of energy transfer is proportional to the projectile velocity, it was convenient to divide the barrel into three separate sections. These correspond to the low, medium and high velocity parts of the projectile motion. Each section is excited by a different method, chosen to satisfy the need for most efficient usage of energy stored in the power supply capacitors. Experiments are described with a breadboard model that test the feasibility of the medium-velocity power conditioning scheme

  2. Design of a dynamic transcranial magnetic stimulation coil system.

    Science.gov (United States)

    Ge, Sheng; Jiang, Ruoli; Wang, Ruimin; Chen, Ji

    2014-08-01

    To study the brain activity at the whole-head range, transcranial magnetic stimulation (TMS) researchers need to investigate brain activity over the whole head at multiple locations. In the past, this has been accomplished with multiple single TMS coils that achieve quasi whole-head array stimulation. However, these designs have low resolution and are difficult to position and control over the skull. In this study, we propose a new dynamic whole-head TMS mesh coil system. This system was constructed using several sagittal and coronal directional wires. Using both simulation and real experimental data, we show that by varying the current direction and strength of each wire, this new coil system can form both circular coils or figure-eight coils that have the same features as traditional TMS coils. Further, our new system is superior to current coil systems because stimulation parameters such as size, type, location, and timing of stimulation can be dynamically controlled within a single experiment.

  3. Globally optimal superconducting magnets part II: symmetric MSE coil arrangement.

    Science.gov (United States)

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2009-01-01

    A globally optimal superconducting magnet coil design procedure based on the Minimum Stored Energy (MSE) current density map is outlined. The method has the ability to arrange coils in a manner that generates a strong and homogeneous axial magnetic field over a predefined region, and ensures the stray field external to the assembly and peak magnetic field at the wires are in acceptable ranges. The outlined strategy of allocating coils within a given domain suggests that coils should be placed around the perimeter of the domain with adjacent coils possessing alternating winding directions for optimum performance. The underlying current density maps from which the coils themselves are derived are unique, and optimized to possess minimal stored energy. Therefore, the method produces magnet designs with the lowest possible overall stored energy. Optimal coil layouts are provided for unshielded and shielded short bore symmetric superconducting magnets.

  4. Eddy current testing probe with dual half-cylindrical coils

    Science.gov (United States)

    Bae, Byung-Hoon; Choi, Jung-Mi; Kim, Soo-Yong

    2000-02-01

    We have developed a new eddy current probe composed of a dual half-cylindrical (2HC) coil as an exciting coil and a sensing coil that is placed in the small gap of the 2HC coil. The 2HC coil induces a linear eddy current on the narrow region within the target medium. The magnitude of eddy current has a maximum peak with the narrow width, underneath the center of the exciting 2HC coil. Because of the linear eddy current, the probe can be used to detect not only the existence of a crack but also its direction in conducting materials. Using specimen with a machined crack, and varying the exciting frequency from 0.5 to 100 kHz, we investigated the relationships between the direction of crack and the output voltage of the sensing coil.

  5. New technique for wiring SSC superconducting sextupole corrector coils

    International Nuclear Information System (INIS)

    Leon, B.

    1985-01-01

    There exists in the electronics industry, a technology for the manufacture of printed circuit (PC) boards which is directly transferable into the creation of highly controlled coils, such as the SSC sextupole superconducting corrector coils. This technology, which uses a process of laying down insulated wire in highly controlled patterns has heretofore been confined exclusively to the manufacture of high density printed circuit (PC) boards, possibly due to an ignorance of its utility in the field of precision winding of coils. This ability to fix wires in a well defined location can be used to produce precision wound coils in a very cost-effective manner. These coils may be superior in quality to conventionally made coils. Before describing what can be created with this technology, it is necessary to take a look at this coil winding process, the MULTIWIRE process, and the industry which has utilized this technology

  6. A new technique for wiring SSC superconducting sextupole corrector coils

    International Nuclear Information System (INIS)

    Leon, B.

    1985-01-01

    There exists in the electronics industry, a technology for the manufacture of printed circuit (PC) boards which is directly transferable into the creation of highly controlled coils, such as the SSC sextupole superconducting corrector coils. This technology, which uses a process of laying down insulated wire in highly controlled patterns, has heretofore been confined excusively to the manufacture of high density printed circuit (PC) boards, possibly due to an ignorance of its utility in the field of precision winding of coils. This ability to fix wires in a well defined location can be used to produce precision wound coils in a very cost-effective manner. These coils may be superior in quality to conventionally made coils. Before describing what can be created with this technology, it is necessary to take a look at this coil winding process, the MULTIWIRE process, and the industry which has utilized this technology

  7. Manufacture and mechanical test of a TORE SUPRA model coil

    International Nuclear Information System (INIS)

    Aymar, R.; Claudet, G.; Disdier, F.; Hamelin, J.; Libeyre, P.; Mayaux, G.; Meuris, C.; Parain, J.; Torossian, A.

    1980-09-01

    Inside the qualifying test programme, supporting the Tore Supra Design, a reduced scale model of a Bsub(T) coil was fabricated by a large industrial firm. This model coil is provided with the same features as those retained for the complete magnet. Tests of this model coil have been carried out in such a way that most of stresses which will arise in Tore Supra windings are simulated; simultaneously its cryogenic supply is fully representative of the system retained for the complete machine. Operation of the model coil has been found highly stable; under the conditions of applied field and forces a coil transition could be triggered, by an electrical heater located inside the coil, only when the temperature of the superfluid helium bath was close to Tsub(lambda). Thus, design and manufacturing techniques have been qualified satisfactorily to proceed to the next step: fabrication of the superconducting Bsub(T) coils of Tore Supra

  8. Focused Ethnography

    Directory of Open Access Journals (Sweden)

    Hubert Knoblauch

    2005-09-01

    Full Text Available In this paper I focus on a distinctive kind of sociological ethnography which is particularly, though not exclusively, adopted in applied research. It has been proposed that this branch of ethno­graphy be referred to as focused ethnography. Focused ethnography shall be delineated within the context of other common conceptions of what may be called conventional ethnography. However, rather than being opposed to it, focused ethno­graphy is rather complementary to conventional ethnography, particularly in fields that are charac­teristic of socially and functionally differentiated contemporary society. The paper outlines the back­ground as well as the major methodological features of focused ethnography, such as short-term field visits, data intensity and time intensity, so as to provide a background for future studies in this area. URN: urn:nbn:de:0114-fqs0503440

  9. Mechanical properties of ISABELLE superconducting coils

    International Nuclear Information System (INIS)

    Thompson, P.; Bertsche, A.; Fuhrmann, J.; Greene, A.; Grove, E.; Repeta, L.; Short, F.; Tannenbaum, M.; Wanderer, P.

    1981-01-01

    As a part of the manufacturing processes, several mechanical measurements are made on ISABELLE dipoles. These are done both to control the process and to provide information for the evaluation of the behavior of the completed magnets. This paper discusses the Young's Modulus (E = 1-3 x 10 6 psi), the thermal contraction of the coil assembly (ΔL/L = 290 +- 17 x 10 -5 at 77 0 K), and the loss of applied prestress with time

  10. Voice coil based scanning probe microscopy

    Czech Academy of Sciences Publication Activity Database

    Klapetek, P.; Valtr, M.; Duchoň, V.; Sobota, Jaroslav

    2012-01-01

    Roč. 7, č. 6 (2012), 332:1-7 ISSN 1931-7573 R&D Projects: GA MPO FR-TI1/241; GA AV ČR KAN311610701; GA MŠk ED0017/01/01 Institutional support: RVO:68081731 Keywords : SPM * Voice coil * Interferometry Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.524, year: 2012

  11. Plan for the large coil program

    International Nuclear Information System (INIS)

    Haubenreich, P.N.; Anderson, W.C.; Luton, J.N.; Thompson, P.B.

    1977-02-01

    This document has been prepared by the Large Coil Program (LCP) to make generally available the information that has been generated up to this point and to indicate the direction of future work. A summary of objectives, general strategy, and implementation of the LCP is given. Expanded descriptions are given of program content, technical requirements, selection of testing arrangements, tentative schedule and method of preliminary cost estimation

  12. LLNL high-field coil program

    International Nuclear Information System (INIS)

    Miller, J.R.

    1986-01-01

    An overview is presented of the LLNL High-Field Superconducting Magnet Development Program wherein the technology is being developed for producing fields in the range of 15 T and higher for both mirror and tokamak applications. Applications requiring less field will also benefit from this program. In addition, recent results on the thermomechanical performance of cable-in-conduit conductor systems are presented and their importance to high-field coil design discussed

  13. Electron Beam Curing of Coil Coatings

    Energy Technology Data Exchange (ETDEWEB)

    Morganstern, K. H. [Radiation Dynamics, Inc., Westbury, NY (United States)

    1969-12-15

    The application of electron accelerators for the rapid curing of coatings on coil processing of steel and aluminium appears to have many practical and economic advantages. This paper discusses this particular application, but in the general framework of electron beam application by industry. Although industry has investigated radiation application for two decades, there have been few applications to date. The reasons for this are discussed as well as the shift in attitude now taking place, indicating a more ready acceptance of radiation processing by industry. This shift is apparent particularly in the coatings field, where the benefits of radiation processing are quite evident. In order to pinpoint these benefits a specific coatings application - coil coating - has been chosen. A typical conventional coil coating line is discussed and compared to a line employing a radiation source. Specific engineering information on the types of electron accelerators suitable for this application; the relative economics of radiation vs. heat curing; and a number of other peripheral advantages of radiation are discussed. (author)

  14. Thermal analysis of track based coils

    Energy Technology Data Exchange (ETDEWEB)

    Davey, K [American MAGLEV, Inc., Edgewater, FL (United States); Zowarka, R [CEM, Austin, TX (United States)

    1996-12-31

    This document examines the temperature rise of coils embedded in a concrete matrix. The ultimate goal is to predict the steady state temperature of the coils subject to a repeated passage of vehicles at a regular interval. The primary concern is in maintaining a maximum temperature which is less than that which would compromise the integrity of the insulation used on the wires. Three techniques are used to examine the problem. First, an analytical approach is used to determine not only the immediate temperature rise of the wire material itself, but also a consevative estimate of the steady state temperature expected. Second, the equations are examined for a one dimensional transient profile of the temperature with time. Finally, a two dimensional steady state boundary element solution is employed to estimate the steady state temperature profile both within the coils and within the rail. In this two dimensional boundary element assessment, an iterative approach is employed to accurately model the heat transfer coefficient h which ultimately defines the steady state temperature. (orig.)

  15. Transcatheter coil embolisation of pulmonary arteriovenous malformations

    International Nuclear Information System (INIS)

    Wingen, M.; Guenther, R.W.

    2001-01-01

    Evaluation of technical success, complications and long-term results of transcatheter coil embolisation in pulmonary arteriovenous malformations (pAVMs). Material and Methods: Transcatheter embolisations of 46 pAVMs in 14 patients were analysed retrospectively, and, 5 years after treatment, the patients were interviewed by telefone concerning persistent symptoms and complications. Main symptoms before embolisation were dyspnoe (86%), hypoxaemia (100%), cerebral ischemia (21%), and hemoptysis (14%); 11 patients (79%) suffered from hereditary hemorrhagic telangiectasia. Results: Embolisation with an average of 3,9 coils (min. 1, max. 19 coils) per pAVM yielded technical success in all cases. Only two minor complications, transitory pleuritis and a small lung infarction were observed. On follow up examination after 5 years either no residual complaints or substantial improvement of dyspnoe were reported; no patient suffered from neurologic or hemorrhagic complications after the embolisation. Conclusion: Transcatheter embolisation is a safe and minimally invasive therapy for pAVMs and has rightfully replaced surgical resection as the therapy of choice. (orig.) [de

  16. Single coil bistable, bidirectional micromechanical actuator

    Science.gov (United States)

    Tabat, Ned; Guckel, Henry

    1998-09-15

    Micromechanical actuators capable of bidirectional and bistable operation can be formed on substrates using lithographic processing techniques. Bistable operation of the microactuator is obtained using a single coil and a magnetic core with a gap. A plunger having two magnetic heads is supported for back and forth linear movement with respect to the gap in the magnetic core, and is spring biased to a neutral position in which the two heads are on each side of the gap in the core. The single electrical coil is coupled to the core and is provided with electrical current to attract one of the heads toward the core by reluctance action to drive the plunger to a limit of travel in one direction. The current is then cut off and the plunger returns by spring action toward the gap, whereafter the current is reapplied to the coil to attract the other head of the plunger by reluctance action to drive the plunger to its other limit of travel. This process can be repeated at a time when switching of the actuator is required.

  17. Quench simulation of SMES consisting of some superconducting coils

    International Nuclear Information System (INIS)

    Noguchi, S.; Oga, Y.; Igarashi, H.

    2011-01-01

    A chain of quenches may be caused by a quench of one element coil when SMES is consists of many element coils. To avoid the chain of quenches, the energy stored in element coil has to be quickly discharged. The cause of the chain of the quenches is the short time constant of the decreasing current of the quenched coil. In recent years, many HTS superconducting magnetic energy storage (HTS-SMES) systems are investigated and designed. They usually consist of some superconducting element coils due to storing excessively high energy. If one of them was quenched, the storage energy of the superconducting element coil quenched has to be immediately dispersed to protect the HTS-SMES system. As the result, the current of the other element coils, which do not reach to quench, increases since the magnetic coupling between the quenched element coil and the others are excessively strong. The increase of the current may cause the quench of the other element coils. If the energy dispersion of the element coil quenched was failed, the other superconducting element coil would be quenched in series. Therefore, it is necessary to investigate the behavior of the HTS-SMES after quenching one or more element coils. To protect a chain of quenches, it is also important to investigate the time constant of the coils. We have developed a simulation code to investigate the behavior of the HTS-SMES. By the quench simulation, it is indicated that a chain of quenches is caused by a quench of one element coil.

  18. ICP-MS based methods to characterize nanoparticles of TiO2 and ZnO in sunscreens with focus on regulatory and safety issues.

    Science.gov (United States)

    Bocca, Beatrice; Caimi, Stefano; Senofonte, Oreste; Alimonti, Alessandro; Petrucci, Francesco

    2018-07-15

    This study sought to develop analytical methods to characterize titanium dioxide (TiO 2 ) and zinc oxide (ZnO) nanoparticles (NPs), including the particle size distribution and concentration, in cream and spray sunscreens with different sun protection factor (SPF). The Single Particle Inductively Coupled Plasma-Mass Spectrometry (SP ICP-MS) was used as screening and fast method to determine particles size and number. The Asymmetric Flow-Field Flow Fractionation (AF4-FFF) as a pre-separation technique was on-line coupled to the Multi-Angle Light Scattering (MALS) and ICP-MS to determine particle size distributions and size dependent multi-elemental concentration. Both methods were optimized in sunscreens in terms of recovery, repeatability, limit of detection and linear dynamic range. Results showed that sunscreens contained TiO 2 particles with an average size of ≤107 nm and also a minor number of ZnO particles sized ≤98 nm. The higher fraction of particles <100 nm was observed in sunscreens with SPF 50+ (ca. 80%); the lower percentage (12-35%) in sunscreens with lower SPF values. Also the higher TiO 2 (up to 24% weight) and ZnO (ca. 0.25% weight) concentrations were found in formulations of SPF 50+. Creamy sunscreens could be considered safe containing TiO 2 and ZnO NPs less than the maximum allowable concentration of 25% weight as set by the European legislation. On the contrary, spray products required additional considerations with regard to the potential inhalation of NPs. The developed methods can contribute to the actual demand for regulatory control and safety assessment of metallic NPs in consumers' products. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. 48{sup th} Annual meeting on nuclear technology (AMNT 2017). Key topic / Enhanced safety and operation excellence. Focus session: Radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Baumann, Erik [New NP GmbH, Erlangen (Germany); Bohnstedt, Angelika [Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Programm Nukleare Entsorgung, Sicherheit und Strahlenforschung (NUSAFE)

    2018-01-15

    The objectives of radiation protection are to minimize the negative health effects due to radiation. Over many past decades, the regulatory environment, i.e. the various international and national codes and standards but also recommendations issued by IAEA and IRCP, was always subject to continuous development reflecting up to date knowledge and experience. Currently, discussions focus on ''new'' areas of human activities like decommissioning and on ''new radioactive substances'' and potential threats associated with their handling (handling and treatment of substances containing naturally occurring radioactive materials). Latter already became subject to regulations issued by EURATOM. For topics like decommissioning, statement can be found doubting that the existing regulations address radiation protection in a sufficient manner.

  20. Design and testing of a coil-unit barrel for helical coil electromagnetic launcher

    Science.gov (United States)

    Yang, Dong; Liu, Zhenxiang; Shu, Ting; Yang, Lijia; Ouyang, Jianming

    2018-01-01

    A coil-unit barrel for a helical coil electromagnetic launcher is described. It provides better features of high structural strength and flexible adjustability. It is convenient to replace the damaged coil units and easy to adjust the number of turns in the stator coils due to the modular design. In our experiments, the highest velocity measured for a 4.5-kg projectile is 47.3 m/s and the mechanical reinforcement of the launcher could bear 35 kA peak current. The relationship between the energy conversion efficiency and the inductance gradient of the launcher is also studied. In the region of low inductance gradient, the efficiency is positively correlated with the inductance gradient. However, in the region of high inductance gradient, the inter-turn arc erosion becomes a major problem of limiting the efficiency and velocity of the launcher. This modular barrel allows further studies in the inter-turn arc and the variable inductance gradient helical coil launcher.

  1. Safety design

    International Nuclear Information System (INIS)

    Kunitomi, Kazuhiko; Shiozawa, Shusaku

    2004-01-01

    JAERI established the safety design philosophy of the HTTR based on that of current reactors such as LWR in Japan, considering inherent safety features of the HTTR. The strategy of defense in depth was implemented so that the safety engineering functions such as control of reactivity, removal of residual heat and confinement of fission products shall be well performed to ensure safety. However, unlike the LWR, the inherent design features of the high-temperature gas-cooled reactor (HTGR) enables the HTTR meet stringent regulatory criteria without much dependence on active safety systems. On the other hand, the safety in an accident typical to the HTGR such as the depressurization accident initiated by a primary pipe rupture shall be ensured. The safety design philosophy of the HTTR considers these unique features appropriately and is expected to be the basis for future Japanese HTGRs. This paper describes the safety design philosophy and safety evaluation procedure of the HTTR especially focusing on unique considerations to the HTTR. Also, experiences obtained from an HTTR safety review and R and D needs for establishing the safety philosophy for the future HTGRs are reported

  2. Large-coil-test-facility fault-tree analysis

    International Nuclear Information System (INIS)

    1982-01-01

    An operating-safety study is being conducted for the Large Coil Test Facility (LCTF). The purpose of this study is to provide the facility operators and users with added insight into potential problem areas that could affect the safety of personnel or the availability of equipment. This is a preliminary report, on Phase I of that study. A central feature of the study is the incorporation of engineering judgements (by LCTF personnel) into an outside, overall view of the facility. The LCTF was analyzed in terms of 32 subsystems, each of which are subject to failure from any of 15 generic failure initiators. The study identified approximately 40 primary areas of concern which were subjected to a computer analysis as an aid in understanding the complex subsystem interactions that can occur within the facility. The study did not analyze in detail the internal structure of the subsystems at the individual component level. A companion study using traditional fault tree techniques did analyze approximately 20% of the LCTF at the component level. A comparison between these two analysis techniques is included in Section 7

  3. Quench detection system of the EURATOM coil for the Large Coil Task

    International Nuclear Information System (INIS)

    Noether, G.; Gauss, S.; Maurer, W.; Siewerdt, L.; Ulbricht, A.; Wuechner, F.

    1989-01-01

    A special quench detection system has been developed for the EURATOM Large Coil Task (LCT) coil. The system is based on a bridge circuit which uses a special 'two in hand' winding technique for the pancakes of the EURATOM LCT coil. The electronic circuit was designed in a fail safe way to prevent failure of the quench detector due to failure of one of its components. A method for quick balancing of the quench detection system in a large toroidal magnet system was applied. The quench detection system worked very reliably during the experimental phase of the LCT and was within the quench detection level setting of 50 mV, i.e. the system was not sensitive to poloidal field transients at or below this level. Non-electrical methods for quench detection were also investigated. (author)

  4. Design of Electromagnetic Moving-coil type Voice Coil Motor for Scanning mirror of Barcode reader

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Bu Hyun; Lee, Jeong Woo; Shim, Hyun Ho; Park, Sang Goo [Hanbat National Univ., Daejeon (Korea, Republic of); Lee, Seung Yop [Sogang Univ., Seoul (Korea, Republic of)

    2016-01-15

    A voice coil actuator with moving coil type for scanning mirror system of barcode reader has been developed. The actuator has a simple structure including a magnet, a coil and a pin. The performance of the actuator is analyzed by a linearized theoretical model. And the dynamic performance of the proposed actuator is predicted through motor constant and restoring constant obtained by finite element simulations. The theoretical model was verified by the prototype which has 64 Hz resonance frequency and 60 deg reflecting angle. We also discovered that that 3 V input can make the actuator rotate over 61.8 deg reflecting angle at 50 Hz resonance frequency. The proposed actuator can simplify its driving configuration because of its implementation of open-loop control.

  5. Spiral Gradient Coil Design for Use in Cylindrical MRI Systems.

    Science.gov (United States)

    Wang, Yaohui; Xin, Xuegang; Liu, Feng; Crozier, Stuart

    2018-04-01

    In magnetic resonance imaging, the stream function based method is commonly used in the design of gradient coils. However, this method can be prone to errors associated with the discretization of continuous current density and wire connections. In this paper, we propose a novel gradient coil design scheme that works directly in the wire space, avoiding the system errors that may appear in the stream function approaches. Specifically, the gradient coil pattern is described with dedicated spiral functions adjusted to allow the coil to produce the required field gradients in the imaging area, minimal stray field, and other engineering terms. The performance of a designed spiral gradient coil was compared with its stream-function counterpart. The numerical evaluation shows that when compared with the conventional solution, the inductance and resistance was reduced by 20.9 and 10.5%, respectively. The overall coil performance (evaluated by the figure of merit (FoM)) was improved up to 26.5% for the x -gradient coil design; for the z-gradient coil design, the inductance and resistance were reduced by 15.1 and 6.7% respectively, and the FoM was increased by 17.7%. In addition, by directly controlling the wire distributions, the spiral gradient coil design was much sparser than conventional coils.

  6. Conceptual Design of Alborz Tokamak Poloidal Coils System

    Science.gov (United States)

    Mardani, M.; Amrollahi, R.

    2013-04-01

    The Alborz tokamak is a D-shape cross section tokamak that is under construction in Amirkabir University of Technology. One of the most important parts of tokamak design is the design of the poloidal field system. This part includes the numbers, individual position, currents and number of coil turns of the magnetic field coils. Circular cross section tokamaks have Vertical Field system but since the elongation and triangularity of plasma cross section shaping are important in improving the plasma performance and stability, the poloidal field coils are designed to have a shaped plasma configuration. In this paper the design of vertical field system and the magnetohydrodynamic equilibrium of axisymmetric plasma, as given by the Grad-Shafranov equation will be discussed. The poloidal field coils system consists of 12 circular coils located symmetrically about the equator plane, six inner PF coils and six outer PF coils. Six outer poloidal field coils (PF) are located outside of the toroidal field coils (TF), and six inner poloidal field coils are wound on the inner legs and are located outside of a vacuum vessel.

  7. Transcranial Magnetic Stimulation-coil design with improved focality

    Science.gov (United States)

    Rastogi, P.; Lee, E. G.; Hadimani, R. L.; Jiles, D. C.

    2017-05-01

    Transcranial Magnetic Stimulation (TMS) is a technique for neuromodulation that can be used as a non-invasive therapy for various neurological disorders. In TMS, a time varying magnetic field generated from an electromagnetic coil placed on the scalp is used to induce an electric field inside the brain. TMS coil geometry plays an important role in determining the focality and depth of penetration of the induced electric field responsible for stimulation. Clinicians and basic scientists are interested in stimulating a localized area of the brain, while minimizing the stimulation of surrounding neural networks. In this paper, a novel coil has been proposed, namely Quadruple Butterfly Coil (QBC) with an improved focality over the commercial Figure-8 coil. Finite element simulations were conducted with both the QBC and the conventional Figure-8 coil. The two coil's stimulation profiles were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils has been done to determine the parameters of interest-volume of stimulation, maximum electric field, location of maximum electric field and area of stimulation across all 50 head models for both coils.

  8. Structural analysis of the NET toroidal field coils and conductor

    International Nuclear Information System (INIS)

    Mitchell, N.; Collier, D.; Gori, R.

    1989-01-01

    The NET toroidal field coils will utilise A15-type superconductor at 4.2 K to generate fields up to 11.5 T. The superconductor strands themselves are sensitive to strain, which causes degradation of their current carrying capacity, and thus the detailed behaviour of the coil conductor must be analysied so that the strian can be minimised. This analysis must include the manufacturing processes of the conductor as well as the normal and abnormal loperational loads. The conductor will be insulated and bonded by glass fibre reinforced epoxy resin, with limited bonding shear strength, and the overall support of the complete coil system must be designed to reduce these shear stresses. The coils will be subjected to pulse loads form the poloidal field coils, and analysis of the slip between the various coil components, such as conductors and the coil case, giving rise to frictional heating and possible loss of superconducting properties is another important factor, which has been investigated by a number of stress analyses. The manufacturing, thermal and normal magnetic loads on the coils and the analysis leading to the proposed structural design are described. In addition to the normal operating conditions, there is a range of abnormal load conditions which could result from electrical or mechanical faults on the coils. The effect of these potential faults has been analysed and the coil design modified to prevent catastrophic structural failure. (author). 13 refs.; 8 figs.; 1 tab

  9. Hydrodynamic studies of CNT nanofluids in helical coil heat exchanger

    Science.gov (United States)

    Babita; Sharma, S. K.; Mital Gupta, Shipra; Kumar, Arinjay

    2017-12-01

    Helical coils are extensively used in several industrial processes such as refrigeration systems, chemical reactors, recovery processes etc to accommodate a large heat transfer area within a smaller space. Nanofluids are getting great attention due to their enhanced heat transfer capability. In heat transfer equipments, pressure drop is one of the major factors of consideration for pumping power calculations. So, the present work is aimed to study hydrodynamics of CNT nanofluids in helical coils. In this study, pressure drop characteristics of CNT nanofluid flowing inside horizontal helical coils are investigated experimentally. The helical coil to tube diameter was varied from 11.71 to 27.34 keeping pitch of the helical coil constant. Double distilled water was used as basefluid. SDBS and GA surfactants were added to stablilize CNT nanofluids. The volumetric fraction of CNT nanofluid was varied from 0.003 vol% to 0.051 vol%. From the experimental data, it was analyzed that the friction factor in helical coils is greater than that of straight tubes. Concentration of CNT in nanofluids also has a significant influence on the pressure drop/friction factor of helical coils. At a constant concentration of CNT, decreasing helical coil to tube diameter from 27.24 to 11.71, fanning friction factor of helical coil; f c increases for a constant value of p/d t. This increase in the value of fanning friction factor can be attributed to the secondary flow of CNT nanofluid in helical coils.

  10. Coil optimisation for transcranial magnetic stimulation in realistic head geometry.

    Science.gov (United States)

    Koponen, Lari M; Nieminen, Jaakko O; Mutanen, Tuomas P; Stenroos, Matti; Ilmoniemi, Risto J

    Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape. We derive a semi-analytical integration scheme for computing the magnetic field energy of an arbitrary surface current distribution, compute the electric field induced by this distribution with a boundary element method, and optimise a TMS coil for focal stimulation. Additionally, we introduce a method for manufacturing such a coil by using Litz wire and a coil former machined from polyvinyl chloride. We designed, manufactured, and validated an optimised TMS coil and applied it to brain stimulation. Our simulations indicate that this coil requires less than half the power of a commercial figure-of-eight coil, with a 41% reduction due to the optimised winding geometry and a partial contribution due to our thinner coil former and reduced conductor height. With the optimised coil, the resting motor threshold of abductor pollicis brevis was reached with the capacitor voltage below 600 V and peak current below 3000 A. The described method allows designing practical TMS coils that have considerably higher efficiency than conventional figure-of-eight coils. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Polymer therapeutics with a coiled coil motif targeted against murine BCL1 leukemia

    Czech Academy of Sciences Publication Activity Database

    Pola, Robert; Laga, Richard; Ulbrich, Karel; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Kabešová, Martina; Kovář, Marek; Pechar, Michal

    2013-01-01

    Roč. 14, č. 3 (2013), s. 881-889 ISSN 1525-7797 R&D Projects: GA ČR GAP301/11/0325; GA AV ČR IAAX00500803 Institutional research plan: CEZ:AV0Z50520514 Institutional support: RVO:61389013 ; RVO:61388971 ; RVO:68378050 Keywords : coiled coil * polymer therapeutics * scFv Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M); EB - Genetics ; Molecular Biology (UMG-J) Impact factor: 5.788, year: 2013

  12. Polymer cancerostatics with a coiled coil motif targeted against murine leukemia

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert; Janoušková, Olga; Sieglová, Irena; Král, Vlastimil; Fábry, Milan; Tomalová, Barbora; Kovář, Marek

    2017-01-01

    Roč. 6, 4 (Suppl) (2017), s. 36 ISSN 2325-9604. [International Conference and Exhibition on Nanomedicine and Drug Delivery. 29.05.2017-31.05.2017, Osaka] R&D Projects: GA ČR(CZ) GA16-17207S Institutional support: RVO:61389013 ; RVO:68378050 ; RVO:61388971 Keywords : coiled coil * polymer cancerostatics * active targeting Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M) https://www.scitechnol.com/conference-abstracts/scientific-tracks-abstracts/nanodelivery-2017-proceedings.html

  13. Coil Migration after Transarterial Coil Embolization of a Splenic Artery Pseudoaneurysm

    Directory of Open Access Journals (Sweden)

    Bezawit D. Tekola

    2013-11-01

    Full Text Available A 48-year-old man with a history of splenic artery pseudoaneurysm requiring transarterial embolization 3 months earlier presented to the emergency department with abdominal pain and fever. Computed tomography showed evidence of embolization coil fragments within the gastrointestinal tract. Upper endoscopy showed a large gastric ulcer with numerous embolization coils extruding into the gastric lumen. The patient underwent partial gastrectomy, distal pancreatectomy and resection of the splenic artery pseudoaneurysm. This case illustrates a rare delayed complication of transarterial embolization of a splenic artery pseudoaneurysm.

  14. Nuclear safety culture and nuclear safety supervision

    International Nuclear Information System (INIS)

    Chai Jianshe

    2013-01-01

    In this paper, the author reviews systematically and summarizes up the development process and stage characteristics of nuclear safety culture, analysis the connotation and characteristics of nuclear safety culture, sums up the achievements of our country's nuclear safety supervision, dissects the challenges and problems of nuclear safety supervision. This thesis focused on the relationship between nuclear safety culture and nuclear safety supervision, they are essential differences, but there is a close relationship. Nuclear safety supervision needs to introduce some concepts of nuclear safety culture, lays emphasis on humanistic care and improves its level and efficiency. Nuclear safety supervision authorities must strengthen nuclear safety culture training, conduct the development of nuclear safety culture, make sure that nuclear safety culture can play significant roles. (author)

  15. Pilot study: safety and effectiveness of simple ultrasound-guided high-intensity focused ultrasound ablating uterine leiomyoma with a diameter greater than 10 cm.

    Science.gov (United States)

    Hou, Ruijie; Wang, Liwei; Li, Shaoping; Rong, Fengmin; Wang, Yuanyuan; Qin, Xuena; Wang, Shijin

    2018-02-01

    The study aimed to prospectively investigate whether uterine leiomyoma greater than 10 cm in diameter could be treated with simple ultrasound-guided high-intensity focused ultrasound (USgHIFU) in one-time treatment. A total of 36 patients with 36 symptomatic uterine leiomyoma greater than 10 cm in diameter who underwent simple USgHIFU treatment alone were analysed. Enhanced MRI was performed before and after HIFU treatment, and all patients had follow-up for 6 months after treatment. Symptom severity scores, treatment time, treatment speed, ablation rate, energy effect ratio, uterine leiomyoma regression rate, adverse events, liver and kidney functions, coagulation function and routine blood count were included in the study endpoints. The mean diameter of uterine leiomyoma was 11.2 ± 1.3 cm (10.0-14.3 cm). The median treatment time and treatment speed were 104.0 min (90.0-140.0 min) and 118.8 cm 3  h -1  (86.2-247.1 cm 3  h -1 ), respectively. The ablation rate of uterine leiomyoma was 71.9 ± 20.4% (32.1-100.0%), and the regression rate of uterine leiomyoma was 40.8 ± 7.5% (25.6-59.9%) at 6 months after treatment. The mean symptom severity scores decreased by an average of approximately 8.6 ± 2.3 (5-14) points. There were no significant changes in haemogram and blood chemical indexes of patients, except for the transient elevation of aspartate aminotransferase, total bilirubin and white blood cells after treatment. No serious adverse reactions occurred. According to our preliminary results, simple USgHIFU is a safe and effective single-treatment method of treating uterine leiomyoma greater than 10 cm in diameter and is an almost innocuous alternative therapeutic strategy. Advances in knowledge: The conclusions indicate simple USgHIFU is safe and effective as one-time treatment of uterine leiomyoma greater than 10 cm in diameter, it could be a promising therapeutic strategy.

  16. Multicenter Off-Label Use of Nit-Occlud Coil in Retrograde Closure of Small Patent Ductus Arteriosus.

    Science.gov (United States)

    Zanjani, Keyhan Sayadpour; Sobhy, Rodina; El-Kaffas, Rania; El-Sisi, Amal

    2017-04-01

    We studied the safety and efficacy of closing patent ductus arteriosus by Nit-Occlud coils via retrograde approach. This is a retrospective study of 46 attempts to close ducts by this method in two hospitals in Egypt and Iran. Ductus arteriosus was crossed by left or right Judkins or endhole catheters. The coil was delivered via the same catheter or the provided endhole catheter after exchange. The procedure was successful in 42 out of 46 attempts. Fluoroscopy and procedural times were significantly shorter when the catheter was not exchanged. This method is effective and safe for the closure of small ducts. Crossing the duct and delivering the coil by a left Judkins catheter is the easiest and fastest way to perform this method.

  17. The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype.

    Directory of Open Access Journals (Sweden)

    Patricia Santos-Valle

    Full Text Available Laminins are large heterotrimeric cross-shaped extracellular matrix glycoproteins with terminal globular domains and a coiled-coil region through which the three chains are assembled and covalently linked. Laminins are key components of basement membranes, and they serve as attachment sites for cell adhesion, migration and proliferation. In this work, we produced a recombinant fragment comprising the entire laminin coiled-coil of the α1-, β1-, and γ1-chains that assemble into a stable heterotrimeric coiled-coil structure independently of the rest of the molecule. This domain was biologically active and not only failed to serve as a substrate for cell attachment, spreading and focal adhesion formation but also inhibited cell adhesion to laminin when added to cells in a soluble form at the time of seeding. Furthermore, gene array expression profiling in cells cultured in the presence of the laminin coiled-coil domain revealed up-regulation of genes involved in cell motility and invasion. These findings were confirmed by real-time quantitative PCR and zymography assays. In conclusion, this study shows for the first time that the laminin coiled-coil domain displays anti-adhesive functions and has potential implications for cell migration during matrix remodeling.

  18. Fifty years of coiled-coils and alpha-helical bundles: a close relationship between sequence and structure.

    Science.gov (United States)

    Parry, David A D; Fraser, R D Bruce; Squire, John M

    2008-09-01

    alpha-Helical coiled coils are remarkable for the diversity of related conformations that they adopt in both fibrous and globular proteins, and for the range of functions that they exhibit. The coiled coils are based on a heptad (7-residue), hendecad (11-residue) or a related quasi-repeat of apolar residues in the sequences of the alpha-helical regions involved. Most of these, however, display one or more sequence discontinuities known as stutters or stammers. The resulting coiled coils vary in length, in the number of chains participating, in the relative polarity of the contributing alpha-helical regions (parallel or antiparallel), and in the pitch length and handedness of the supercoil (left- or right-handed). Functionally, the concept that a coiled coil can act only as a static rod is no longer valid, and the range of roles that these structures have now been shown to exhibit has expanded rapidly in recent years. An important development has been the recognition that the delightful simplicity that exists between sequence and structure, and between structure and function, allows coiled coils with specialized features to be designed de novo.

  19. Split coil made of (RE)BCO pancake coils for IC(B) anisotropy measurements of superconductors

    International Nuclear Information System (INIS)

    Frolek, L; Pardo, E; Gömöry, F; Šouc, J; Pitel, J

    2014-01-01

    Measurement of the I c (B) anisotropy is standard characterization of superconducting tapes, wires or cables. This contribution presents a split coil consisting on two superconducting pancake coils in order to generate the magnetic field necessary for this kind of measurement. Both coils were made using (RE)BCO – based second generation (2G) coated conductor tape with cross section 0.1 mm × 12 mm. The individual turns of the tape were insulated by a fiberglass tape without impregnation. These coils have identical inner and outer diameter and number of turns. Their inner and outer diameters are 50 mm and 80 mm, respectively, and they have 62 turns. The length of conductor in each coil is approximately 13 m. The distance between both pancake coils is 22 mm. Individual coils and the complete split coil were characterized in liquid nitrogen bath. Their parameters, like the critical currents, E(I) characteristics and magnetic field of complete split coil, were measured and interpreted. The split coil can be used up to magnetic fields of 210 mT. The length between the potential taps on the sample can be up to 20 mm, while the magnetic field decrease is lower than 1% on this length.

  20. Comparison of the association of sac growth and coil compaction with recurrence in coil embolized cerebral aneurysms.

    Directory of Open Access Journals (Sweden)

    Anna L Hoppe

    Full Text Available In recurrent cerebral aneurysms treated by coil embolization, coil compaction is regarded as the presumptive mechanism. We test the hypothesis that aneurysm growth is the primary recurrence mechanism. We also test the hypothesis that the coil mass will translate a measurable extent when recurrence occurs.An objective, quantitative image analysis protocol was developed to determine the volumes of aneurysms and coil masses during initial and follow-up visits from 3D rotational angiograms. The population consisted of 15 recurrence and 12 non-recurrence control aneurysms initially completely coiled at a single center. An investigator sensitivity study was performed to assess the objectivity of the methods. Paired Wilcoxon tests (p<0.05, one-tailed were performed to assess for aneurysm and coil growth. The translation of the coil mass center at follow-up was computed. A Mann Whitney U-Test (p<0.05, one-tailed was used to compare translation of coil mass centers between recurrence and control subjects.Image analysis protocol was found to be insensitive to the investigator. Aneurysm growth was evident in the recurrence cohort (p=0.003 but not the control (p=0.136. There was no evidence of coil compaction in either the recurrence or control cohorts (recurrence: p=0.339; control: p=0.429. The translation of the coil mass centers was found to be significantly larger in the recurrence cohort than the control cohort (p=0.047.Aneurysm sac growth, not coil compaction, was the primary mechanism of recurrence following successful coil embolization. The coil mass likely translates to a measurable extent when recurrence occurs and has the potential to serve as a non-angiographic recurrence marker.

  1. Without 'Focus'

    Directory of Open Access Journals (Sweden)

    Aldo Sevi

    2010-12-01

    Full Text Available It is widely accepted that a notion of 'focus', more or less as conceived of in Jackendoff (1972, must be incorporated into our theory of grammar, as a means of accounting for certain observed correlations between prosodic facts and semantic/pragmatic facts. In this paper, we put forth the somewhat radical idea that the time has come to give up this customary view, and eliminate 'focus' from our theory of grammar. We argue that such a move is both economical and fruitful.Research over the years has revealed that the correlations between prosody, 'focus', and the alleged semantic/pragmatic effects of focus are much less clear and systematic than we may have initially hoped. First we argue that this state of affairs detracts significantly from the utility of our notion of 'focus', to the point of calling into question the very motivation for including it in the grammar. Then we look at some of the central data, and show how they might be analyzed without recourse to a notion of 'focus'. We concentrate on (i the effect of pitch accent placement on discourse congruence, and (ii the choice of 'associate' for the so-called 'focus sensitive' adverb only. We argue that our focus-free approach to the data improves empirical coverage, and begins to reveal patterns that have previously been obscured by preconceptions about 'focus'.ReferencesBeaver, D. & Clark, B. 2008. Sense and Sensitivity: How Focus Determines Meaning. Blackwell.Beaver, D., Clark, B., Flemming, E., Jaeger, T. F. & Wolters, M. 2007. ‘When semantics meets phonetics: Acoustical studies of second occurrence focus’. Language 83.2: 245–76.http://dx.doi.org/10.1353/lan.2007.0053Beckman, M. & Hirschberg, J. 1994. ‘The ToBI Annotation Conventions’. Ms.,http://www.cs.columbia.edu/~julia/files/conv.pdf.Bolinger, D. 1972. ‘Accent is predictable (if you are a mind-reader’. Language 48.3: 633–44.http://dx.doi.org/10.2307/412039Büring, D. 2006. ‘Focus projection and default

  2. Electromagnetic results of the Japanese LCT coil's domestic test

    International Nuclear Information System (INIS)

    Nishi, Masataka; Okuno, Kiyoshi; Takahashi, Yoshikazu; Tsuji, Hiroshi; Ando, Toshinari; Shimamoto, Susumu

    1984-01-01

    The domestic test of the Japanese LCT coil was carried out in 1982. During this test, the coil was charged up to the single coil's 100% state (10.22kA, 6.4T, 106MJ) four times and experienced no quenche. at the 100% charging state, coil stability was tested by using heaters installed in the conductor. A half turn length normal zone (about 5 m) generated by heaters was spontenously disappeared in 2 second. This normalized zone included the highest magnetic field position. The transport current which gives the stable limit is extraporated to be about 12.5kA at 8T by this test result. The dump test was carried out also from the 100% charging state. At that time, about 90% of the coil's stored energy was extracted by the dump resistor and the coil was not damaged. (author)

  3. Mechanical behavior of the ATLAS B0 model coil

    CERN Document Server

    Foussat, A; Acerbi, E; Alessandria, F; Berthier, R; Broggi, F; Daël, A; Dudarev, A; Mayri, C; Miele, P; Reytier, M; Rossi, L; Sorbi, M; Sun, Z; ten Kate, H H J; Vanenkov, I; Volpini, G

    2002-01-01

    The ATLAS B0 model coil has been developed and constructed to verify the design parameters and the manufacture techniques of the Barrel Toroid coils (BT) that are under construction for the ATLAS Detector. Essential for successful operation is the mechanical behavior of the superconducting coil and its support structure. In the ATLAS magnet test facility, a magnetic mirror is used to reproduce in the model coil the electromagnetic forces of the BT coils when assembled in the final Barrel Toroid magnet system. The model coil is extensively equipped with mechanical instrumentation to monitor stresses and force levels as well as contraction during a cooling down and excitation up to nominal current. The installed set up of strain gauges, position sensors and capacitive force transducers is presented. Moreover the first mechanical results in terms of expected main stress, strain and deformation values are presented based on detailed mechanical analysis of the design. (7 refs).

  4. Investigation of the mechanical and electrical properties of superconducting coils

    International Nuclear Information System (INIS)

    Saito, T.; Yamagiwa, T.; Hara, K.; Kojima, Y.; Hosoyama, K.; Mori, A.; Nojima, K.; Okamoto, Y.; Takabayashi, S.; Tanaka, T.

    1994-01-01

    Measurement of elastic (Young's) modulus of the superconducting coil and electrical punch-through test have been performed at LBL to understand the mechanical and electrical properties of the superconducting coils. The authors have investigated the elastic modulus of the superconducting coils with six kinds of insulators (made with polyimide-fiberglass-epoxy and all polyimide insulation with epoxy/polyimide adhesive) at room and liquid nitrogen temperatures using samples made of 10 stacks of superconducting cables. The samples are cured under varying compression to investigate the curing pressure dependence of Young's modulus of the coils with six kinds of the insulation system. The electrical punch-through test has also performed under compression at room and liquid nitrogen temperatures to investigate electrical integrity of the insulated coils. The tensile strength test of four kinds of polyimide films has been performed at various temperatures (between cryogenic and coil curing temperatures) to understand the mechanical properties of the films

  5. An automated coil winding machine for the SSC dipole magnets

    International Nuclear Information System (INIS)

    Kamiya, S.; Iwase, T.; Inoue, I.; Fukui, I.; Ishida, K.; Kashiwagi, S.; Sato, Y.; Yoshihara, T.; Yamamoto, S.; Johnson, E.; Gibson, C.

    1990-01-01

    The authors have finished the preliminary design of a fully automated coil winding machine that can be used to manufacture the large number of SSC dipole magnets. The machine aims to perform all coil winding operations including coil parts inserting without human operators at a high productive rate. The machine is composed of five industrial robots. In order to verify the design, they built a small winding machine using an industrial robot and successfully wound a 1 meter long coil using SSC dipole magnet wire. The basic design for the full length coil and the robot winding technique are described in this paper. A fully automated coil winding machine using standard industrial components would be very useful if duplicate production lines are used. 5 figs., 1 tab

  6. Particle-in-cell simulations of magnetically driven reconnection using laser-powered capacitor coils

    Science.gov (United States)

    Huang, Kai; Lu, Quanming; Gao, Lan; Ji, Hantao; Wang, Xueyi; Fan, Feibin

    2018-05-01

    In this paper, we propose an experimental scheme to fulfill magnetically driven reconnections. Here, two laser beams are focused on a capacitor-coil target and then strong currents are wired in two parallel circular coils. Magnetic reconnection occurs between the two magnetic bubbles created by the currents in the two parallel circular coils. A two-dimensional particle-in-cell simulation model in the cylindrical coordinate is used to investigate such a process, and the simulations are performed in the (r ,z ) plane. The results show that with the increase of the currents in the two coils, the associated magnetic bubbles expand and a current sheet is formed between the two bubbles. Magnetic reconnection occurs when the current sheet is sufficiently thin. A quadrupole structure of the magnetic field in the θ direction ( Bθ ) is generated in the diffusion region and a strong electron current along the r direction ( Je r ) is also formed due to the existence of the high-speed electron flow away from the X line in the center of the outflow region. Because the X line is a circle along the θ direction, the convergence of the plasma flow around r =0 will lead to the asymmetry of Je r and Bθ between the two outflow regions of magnetic reconnection.

  7. Thermo-mechanical analysis of RMP coil system for EAST tokamak

    International Nuclear Information System (INIS)

    Wang, Songke; Ji, Xiang; Song, Yuntao; Zhang, Shanwen; Wang, Zhongwei; Sun, Youwen; Qi, Minzhong; Liu, Xufeng; Wang, Shengming; Yao, Damao

    2014-01-01

    Highlights: • Thermal design requirements for EAST RMP coils are summarized. • Cooling parameters based on both theoretical and numerical solutions are determined. • Compromise between thermal design and structural design is made on number of turns. • Thermo-mechanical calculations are made to validate its structural performance. - Abstract: Resonant magnetic perturbation (RMP) has been proved to be an efficient approach on edge localized modes (ELMs) control, resistive wall mode (RWM) control, and error field correction (EFC), RMP coil system under design in EAST tokamak will realize the above-mentioned multi-functions. This paper focuses on the thermo-mechanical analysis of EAST RMP coil system on the basis of sensitivity analysis, both normal and off-normal working conditions are considered. The most characteristic set of coil system is chosen with a complete modelling by means of three-dimensional (3D) finite element method, thermo-hydraulic and thermal-structural performances are investigated adequately, both locally and globally. The compromise is made between thermal performance and structural design requirements, and the results indicate that the optimized design is feasible and reasonable

  8. Sound Coiled-Tubing Drilling Practices

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Thomas; Deskins, Greg (Maurer Technology Inc.); Ward, Stephen L. (Advantage Energy Services Ltd); Hightower, Mel

    2001-09-30

    This Coiled-Tubing Drilling (CTD) Sound Practices Manual provides tools needed by CTD engineers and supervisors to plan, design and perform safe, successful CTD operations. As emphasized throughout, both careful planning and attention to detail are mandatory for success. A bibliography of many useful CTD references is presented in Chapter 6. This manual is organized according to three processes: 1) Pre-Job Planning Process, 2) Operations Execution Process, and 3) Post-Job Review Process. Each is discussed in a logical and sequential format.

  9. Coil for a nuclear fusion device

    International Nuclear Information System (INIS)

    Kadotani, Kenzo.

    1975-01-01

    Object: To provide a thin nuclear fusion coil having good thermal insulation and insulating properties in which mica and glass materials are wound round conductors subjected to varnish treatment and hardened, which is then sealed into a metallic case along with negative gases of more than two atmospheric pressures. Structure: A plurality of conductors impregnated with varnish are hardened by a rare insulating layer, after which it is coated with a layer of mica not impregnated with varnish and a layer of glass substance and is then received into a metallic case and filled under pressure with negative gases at a pressure more than two atmospheric pressures. (Kamimura, M.)

  10. MRI of the orbit with surface coils

    International Nuclear Information System (INIS)

    Reuther, G.; Requardt, H.; Siemens A.G., Erlangen

    1986-01-01

    MRI of the orbit is strongly improved by the use of surface coils due to a higher signal-to-noise ratio. Oblique views without moving the patient present the optic nerve in full length on one slice. First experience with a small number of cases demonstrates normal anatomy and lesions in detail only at T 1 -weighted pulse sequences. Losses in contrast variation and detail accuracy are caused by movements of the eyeballs. Edge artifacts due to chemical shifting impair the image quality. So far there are no pinters towards tissue-specific signal intensity behaviour. Procedure and most favourable parameters at 1 tesla are given. (orig.) [de

  11. A large stellarator based on modular coils

    International Nuclear Information System (INIS)

    Hamberger, S.M.; Sharp, L.E.; Petersen, L.F.

    1979-06-01

    Although stellarators offer some considerable advantages over tokamaks, difficulties arise in designing large devices due, for instance, to poor plasma access as well as to constructional electromechanical and maintenance problems associated with continous helical windings. This paper describes a design for a fairly large device (major radius 2.1m), based on a set of discrete coil modules arranged in a toroidal configuration to provide the required closed magnetic surfaces, having gaps for unobstructed access to the plasma for diagnostics, etc, and allowing for easy removal for maintenance

  12. Mechanical properties of ISABELLE superconducting coils

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, P.; Bertsche, A.; Fuhrmann, J.; Greene, A.; Grove, E.; Repeta, L.; Short, F.; Tannenbaum, M.; Wanderer, P.

    1981-01-01

    As a part of the manufacturing processes, several mechanical measurements are made on ISABELLE dipoles. These are done both to control the process and to provide information for the evaluation of the behavior of the completed magnets. This paper discusses the Young's Modulus (E = 1-3 x 10/sup 6/ psi), the thermal contraction of the coil assembly (..delta..L/L = 290 +- 17 x 10/sup -5/ at 77/sup 0/K), and the loss of applied prestress with time (approx. 20% for times 20 days).

  13. General Atomic's superconducting toroidal field coil concept

    International Nuclear Information System (INIS)

    Alcorn, J.; Purcell, J.

    1978-01-01

    General Atomic's concept for a superconducting toroidal field coil is presented. The concept is generic for large tokamak devices, while a specific design is indicated for a 3.8 meter (major radius) ignition/burn machine. The concept utilizes bath cooled NbTi conductor to generate a peak field of 10 tesla at 4.2 K. The design is simple and straightforward, requires a minimum of developmental effort, and draws extensively upon the perspective of past experience in the design and construction of large superconducting magnets for high energy physics. Thus, the primary emphasis is upon economy, reliability, and expeditious construction scheduling. (author)

  14. New superconducting coil configuration for energy storage

    International Nuclear Information System (INIS)

    Tokorabet, M.; Mailfert, A.; Colteu, A.

    1998-01-01

    Energy storage using superconducting coils involves the problem of electromagnetic field pollution outside the considered system. Different configurations are widely studied: the torus, the alone solenoid and multiple parallel solenoids enclosed in one container. A new configuration which minimizes the external pollution is studied in this paper. The theoretical system is composed of two spherical distributions of the current which are concentric. The analytical study uses solution of Laplace equations. Parametric study covers energy, flux density and geometrical data. The second study concerns the numerical approach of this design using coaxial solenoids. A comparison between this new system and the known systems is presented as a conclusion. (orig.)

  15. Analytical solutions to SSC coil end design

    International Nuclear Information System (INIS)

    Bossert, R.C.; Brandt, J.S.; Carson, J.A.; Fulton, H.J.; Lee, G.C.; Cook, J.M.

    1989-03-01

    As part of the SCC magnet effort, Fermilab will build and test a series of one meter model SSC magnets. The coils in these magnets will be constructed with several different end configurations. These end designs must satisfy both mechanical and magnetic criteria. Only the mechanical problem will be addressed. Solutions will attempt to minimize stresses and provide internal support for the cable. Different end designs will be compared in an attempt to determine which is most appropriate for the SSC dipole. The mathematics required to create each end configuration will be described. The computer aided design, programming and machine technology needed to make the parts will be reviewed. 2 refs., 10 figs

  16. Field Demonstraton of Existing Microhole Coiled Tubing Rig (MCTR) Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kent Perry; Samih Batarseh; Sheriff Gowelly; Thomas Hayes

    2006-05-09

    time is divided among the remaining four functions of rig up/rig down, logging, lay down bottomhole assembly, and pick up bottomhole assembly. Observations made during all phases of CT rig operation at each of the project well installations have verified a number of characteristics of the technology that represent advantages that can produce significant savings of 25-35 percent per well. Attributes of the CT rig performance include: (1) Excellent hole quality with hole deviation amounting to 1-2 degrees; (2) Reduced need for auxiliary equipment; (3) Efficient rig mobilization requiring only four trailers; (4) Capability of ''Zero Discharge'' operation; (5) Improved safety; and, (6) Measurement while drilling capability. In addition, commercial cost data indicates that the CT rig reduces drilling costs by 25 to 35% compared to conventional drilling technology. Widespread commercial use of the Microhole Coiled Tubing technology in the United States for onshore Lower-48 drilling has the potential of achieving substantially positive impacts in terms of savings to the industry and resource expansion. Successfully commercialized Microhole CT Rig Technology is projected to achieve cumulative savings in Lower-48 onshore drilling expenditures of approximately 6.8 billion dollars by 2025. The reduced cost of CT microhole drilling is projected to enable the development of gas resources that would not have been economic with conventional methods. Because of the reduced cost of drilling achieved with CT rig technology, it is estimated that an additional 22 Tcf of gas resource will become economic to develop. In the future, the Microhole Coiled Tubing Rig represents an important platform for the continued improvement of drilling that draws on a new generation of various technologies to achieve goals of improved drilling cost and reduced impact to the environment.

  17. Transmit coil design for Wireless Power Transfer for medical implants.

    Science.gov (United States)

    Lemdiasov, Rosti; Venkatasubramanian, Arun

    2017-07-01

    A new design approach for the design of transmit coils for Wireless Power Transfer (WPT) is presented. The theoretical formulation involves a figure of merit that has to be maximized to solve for the surface current. Numerical predictions and comparisons with practical measurements for the coil parameters (inductance. resistance) underscore the success of this approach in terms of achieving strong coupling with a receive coil while maintaining low resistance.

  18. MRI surface-coil pair with strong inductive coupling.

    Science.gov (United States)

    Mett, Richard R; Sidabras, Jason W; Hyde, James S

    2016-12-01

    A novel inductively coupled coil pair was used to obtain magnetic resonance phantom images. Rationale for using such a structure is described in R. R. Mett et al. [Rev. Sci. Instrum. 87, 084703 (2016)]. The original rationale was to increase the Q-value of a small diameter surface coil in order to achieve dominant loading by the sample. A significant improvement in the vector reception field (VRF) is also seen. The coil assembly consists of a 3-turn 10 mm tall meta-metallic self-resonant spiral (SRS) of inner diameter 10.4 mm and outer diameter 15.1 mm and a single-loop equalization coil of 25 mm diameter and 2 mm tall. The low-frequency parallel mode was used in which the rf currents on each coil produce magnetic fields that add constructively. The SRS coil assembly was fabricated and data were collected using a tissue-equivalent 30% polyacrylamide phantom. The large inductive coupling of the coils produces phase-coherency of the rf currents and magnetic fields. Finite-element simulations indicate that the VRF of the coil pair is about 4.4 times larger than for a single-loop coil of 15 mm diameter. The mutual coupling between coils influences the current ratio between the coils, which in turn influences the VRF and the signal-to-noise ratio (SNR). Data on a tissue-equivalent phantom at 9.4 T show a total SNR increase of 8.8 over the 15 mm loop averaged over a 25 mm depth and diameter. The experimental results are shown to be consistent with the magnetic resonance theory of the emf induced by spins in a coil, the theory of inductively coupled resonant circuits, and the superposition principle. The methods are general for magnetic resonance and other types of signal detection and can be used over a wide range of operating frequencies.

  19. Magnet coils made from high-temperature superconductor

    International Nuclear Information System (INIS)

    Jenkins, R.G.; Yang, M.; Grovenor, C.R.M.; Goringe, M.J.

    1996-01-01

    We review the progress we have made in constructing HTS coils and report our latest results. Also we describe the cryogen-free operation of one of our HTS coils cooled to 55 K using a Stirling cycle cryocooler. Lastly, we describe how 4 Oxford coils are being used in a project to investigate the controllability of HTS magnets in applications such as ''maglev'' suspension systems. We briefly report the initial findings of this work and describe developments in progress. (orig.)

  20. Invited review the coiled coil silk of bees, ants, and hornets.

    Science.gov (United States)

    Sutherland, Tara D; Weisman, Sarah; Walker, Andrew A; Mudie, Stephen T

    2012-06-01

    In this article, we review current knowledge about the silk produced by the larvae of bees, ants, and hornets [Apoidea and Vespoidea: Hymenoptera]. Different species use the silk either alone or in composites for a variety of purposes including mechanical reinforcement, thermal regulation, or humidification. The characteristic molecular structure of this silk is α-helical proteins assembled into tetrameric coiled coils. Gene sequences from seven species are available, and each species possesses a copy of each of four related silk genes that encode proteins predicted to form coiled coils. The proteins are ordered at multiple length scales within the labial gland of the final larval instar before spinning. The insects control the morphology of the silk during spinning to produce either fibers or sheets. The silk proteins are small and non repetitive and have been produced artificially at high levels by fermentation in E. coli. The artificial silk proteins can be fabricated into materials with structural and mechanical properties similar to those of native silks. Copyright © 2011 Wiley Periodicals, Inc.

  1. d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

    DEFF Research Database (Denmark)

    Ruckthong, Leela; Peacock, Anna F.A.; Pascoe, Cherilyn E.

    2017-01-01

    Although metal ion binding to naturally occurring l-amino acid proteins is well documented, understanding the impact of the opposite chirality (d-)amino acids on the structure and stereochemistry of metals is in its infancy. We examine the effect of a d-configuration cysteine within a designed l......-amino acid three-stranded coiled coil in order to enforce a precise coordination number on a metal center. The d chirality does not alter the native fold, but the side-chain re-orientation modifies the sterics of the metal binding pocket. l-Cys side chains within the coiled-coil structure have previously...... by comparison of the structure of ZnIICl(CSL16DC)3 2- to the published structure of ZnII(H2O)(GRAND-CSL12AL16LC)3 -. Moreover, spectroscopic analysis indicates that the CdII geometry observed by using l-Cys ligands (a mixture of three- and four-coordinate CdII) is altered to a single four-coordinate species...

  2. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Shannon E.; Nguyen, Elaine; Donegan, Rebecca K.; Patterson-Orazem, Athéna C.; Hazel, Anthony; Gumbart, James C.; Lieberman, Raquel L.

    2017-11-01

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma.

  3. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.

    Science.gov (United States)

    Hill, Shannon E; Nguyen, Elaine; Donegan, Rebecca K; Patterson-Orazem, Athéna C; Hazel, Anthony; Gumbart, James C; Lieberman, Raquel L

    2017-11-07

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Magnetic field alignment of coil-coil diblock copolymers and blends via intrinsic chain anisotropy

    Science.gov (United States)

    Rokhlenko, Yekaterina; Majewski, Pawel; Larson, Steven; Yager, Kevin; Gopalan, Padma; Avgeropoulos, Apostolos; Chan, Edwin; Osuji, Chinedum

    Magnetic fields can control alignment of self-assembled soft materials such as block copolymers provided there is a suitably large magnetic susceptibility anisotropy present in the system. Recent results have highlighted the existence of a non-trivial intrinsic anisotropy in coil-coil diblock copolymers, specifically in lamellar-forming PS-b-P4VP, which enables alignment at field strengths of a few tesla in systems lacking mesogenic components. Alignment is predicated on correlation in the orientation of end-end vectors implied by the localization of block junctions at the microdomain interface and is observed on cooling across the order-disorder transition in the presence of the field. For appropriate combinations of field strength and grain size, we can leverage intrinsic chain anisotropy to magnetically direct self-assembly of many non-mesogenic systems, including other coil-coil BCPs like PS-b-PDMS and PS-b-PMMA, blends of BCPs of disparate morphologies and MWs, and blends of BCPs with homopolymers. This is noteworthy as blends of PS-b-P4VP with PEO provide a route to form functional materials such as nanoporous films by dissolution of PEO, or aligned ion conduction materials. We survey these various systems using TEM and in-situ X-ray scattering to study the phase behavior and temperature-, time- and field- dependent dynamics of alignment.

  5. Structure of a designed, right-handed coiled-coil tetramer containing all biological amino acids.

    Science.gov (United States)

    Sales, Mark; Plecs, Joseph J; Holton, James M; Alber, Tom

    2007-10-01

    The previous design of an unprecedented family of two-, three-, and four-helical, right-handed coiled coils utilized nonbiological amino acids to efficiently pack spaces in the oligomer cores. Here we show that a stable, right-handed parallel tetrameric coiled coil, called RH4B, can be designed entirely using biological amino acids. The X-ray crystal structure of RH4B was determined to 1.1 Angstrom resolution using a designed metal binding site to coordinate a single Yb(2+) ion per 33-amino acid polypeptide chain. The resulting experimental phases were particularly accurate, and the experimental electron density map provided an especially clear, unbiased view of the molecule. The RH4B structure closely matched the design, with equivalent core rotamers and an overall root-mean-square deviation for the N-terminal repeat of the tetramer of 0.24 Angstrom. The clarity and resolution of the electron density map, however, revealed alternate rotamers and structural differences between the three sequence repeats in the molecule. These results suggest that the RH4B structure populates an unanticipated variety of structures.

  6. A Feasibility Study. Ductless Hydronic Distribution Systems with Fan Coil Delivery

    Energy Technology Data Exchange (ETDEWEB)

    Springer, D. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Dakin, B. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Backman, C. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States)

    2012-07-01

    The primary objectives of this study are to estimate potential energy savings relative to conventional ducted air distribution, and to identify equipment requirements, costs, and barriers with a focus on ductless hydronic delivery systems that utilize water-to-air terminal units in each zone. Results indicate that annual heating and cooling energy use can be reduced by up to 27% assuming replacement of the conventional 13 SEER heat pump and coil with a similarly rated air-to-water heat pump.

  7. Poster - Thur Eve - 13: Quantifying specific absorption rate of shielded RF coils through electromagnetic simulations for 7-T MRI.

    Science.gov (United States)

    Belliveau, J-G; Gilbert, K M; Abou-Khousa, M; Menon, R S

    2012-07-01

    Ultra-high field MRI has many advantages such as increasing spatial resolution and exploiting contrast never before seen in-vivo. This contrast has been shown to be beneficial for many applications such as monitoring early and late effect to radiation therapy and transient changes during disease to name a few. However, at higher field strengths the RF wave, needed to for transmitting and receiving signal, approaches that of the head. This leads to constructive and deconstructive interference and a non -uniform flip angle over the volume being imaged. A transmit or transceive RF surface coil arrays is currently a method of choice to overcome this problem; however, mutual inductance between elements poses a significant challenge for the designer. A method to decouple elements in such an array is by using circumferential shielding; however, the potential benefits and/or disadvantages have not been investigated. This abstract primarily focuses on understanding power deposition - measured through Specific Absorption Rate - in the sample using circumferentially shielded RF coils. Various geometries of circumferentially shielded coils are explored to determine the behaviour of shield width and its effect on required transmit power and power deposition to the sample. Our results indicate that there is an optimization on shield width depending on the imaging depth. Additionally, the circumferential shield focuses the field more than unshielded coils, meaning that slight SAR may even be lower for circumferential shielded RF coils in array. © 2012 American Association of Physicists in Medicine.

  8. Coil extensions improve line shapes by removing field distortions

    Science.gov (United States)

    Conradi, Mark S.; Altobelli, Stephen A.; McDowell, Andrew F.

    2018-06-01

    The static magnetic susceptibility of the rf coil can substantially distort the field B0 and be a dominant source of line broadening. A scaling argument shows that this may be a particular problem in microcoil NMR. We propose coil extensions to reduce the distortion. The actual rf coil is extended to a much longer overall length by abutted coil segments that do not carry rf current. The result is a long and nearly uniform sheath of copper wire, in terms of the static susceptibility. The line shape improvement is demonstrated at 43.9 MHz and in simulation calculations.

  9. Performance verification tests of JT-60SA CS model coil

    Energy Technology Data Exchange (ETDEWEB)

    Obana, Tetsuhiro, E-mail: obana.tetsuhiro@LHD.nifs.ac.jp [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Murakami, Haruyuki [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan); Takahata, Kazuya; Hamaguchi, Shinji; Chikaraishi, Hirotaka; Mito, Toshiyuki; Imagawa, Shinsaku [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Kizu, Kaname; Natsume, Kyohei; Yoshida, Kiyoshi [Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan)

    2015-11-15

    Highlights: • The performance of the JT-60SA CS model coil was verified. • The CS model coil comprised a quad-pancake wound with a Nb{sub 3}Sn CIC conductor. • The CS model coil met the design requirements. - Abstract: As a final check of the coil manufacturing method of the JT-60 Super Advanced (JT-60SA) central solenoid (CS), we verified the performance of a CS model coil. The model coil comprised a quad-pancake wound with a Nb{sub 3}Sn cable-in-conduit conductor. Measurements of the critical current, joint resistance, pressure drop, and magnetic field were conducted in the verification tests. In the critical-current measurement, the critical current of the model coil coincided with the estimation derived from a strain of −0.62% for the Nb{sub 3}Sn strands. As a result, critical-current degradation caused by the coil manufacturing process was not observed. The results of the performance verification tests indicate that the model coil met the design requirements. Consequently, the manufacturing process of the JT-60SA CS was established.

  10. Reactivation of Open Coil Springs: A Novel Procedure

    Directory of Open Access Journals (Sweden)

    Sanjeeb Kumar Sahu

    2012-01-01

    Full Text Available Open coil springs are commonly used in orthodontic practice to create space for a palatally or lingually blocked out tooth. However, very often the clinician encounters a situation where the inter-bracket span is very less and the open coil spring is not long enough to open the required space needed for alignment. In such situations, the clinician needs to remove the arch wire and reinserts a longer coil spring. A new simple and cost-effective technique describes an intraoral reactivation of an open coil spring without the need for removal of the base archwire with the additional benefit of preventing unwanted forces to the adjacent teeth.

  11. Switching transients in the MFTF yin-yang coils

    International Nuclear Information System (INIS)

    Owen, E.W.; Shimer, D.W.

    1982-01-01

    This report is a study of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to the coils' performance tests

  12. Coil Array Design Inspired on the Kepler's Lenten Pretzel

    International Nuclear Information System (INIS)

    Vazquez, F.; Solis, S. E.; Rodriguez, A. O.

    2008-01-01

    The RF coil arrays are an important part in Magnetic Resonance Imaging, since they are the main device for transmission and reception of the magnetic resonance signal. An RF coil array with a new configuration based on the Kepler's Lenten pretzel for the geocentric path of Mars is proposed in this work. The evenly distributed trajectories may serve as the basic configuration to form a coil array to adequately cover a region of interest for magnetic resonance experiments. The main goal is to investigate the electromagnetic properties of this coil array geometry to obtain an optimal design for its further construction. Hence, the electromagnetic properties of the coil array were numerical simulated using the finite element method and the quasi-static approach. Resulting simulations showed that there is an important concentration of magnetic field lines at the centre of the coil array. This is an advantage over other coil arrays where the magnetic field usually decreased at their geometrical centre. Both the electric and magnetic fields had also a very good uniformity. These characteristics made this coil design a good candidate for applications where the use of multi-coil technology is mandatory

  13. Protection of large-stored-energy superconducting coils

    International Nuclear Information System (INIS)

    Kircher, F.

    1975-11-01

    When the stored energy of superconducting magnets increases, the problem of the protection of the coil when a quench occurs becomes more and more important, especially if the structure of the coil is such that the energy can be dissipated only in a small part of the coil. The aim of this paper is first to describe a program which enables to predict the increase of temperature inside the coil for several kinds of protection and to give results for KEK pulsed dipoles (under construction and planned for TRISTAN). (auth.)

  14. Magnetic field, inductance of circular coil and solenoids

    International Nuclear Information System (INIS)

    Ramirez Hoyos, P.; Barbero Garcia, A.J.; Mafe Matoses, S.

    1995-01-01

    The self-inductance of a current-carrying circular coil and the mutual inductances of the Helmholtz coils and coil-sole-noid systems have been measured and calculated theoretically. The experiments and the required equipment are suited to an undergraduate laboratory. The theoretical calculation involve the use of simple numerical integration methods for evaluating the magnetic field of the circular coil and the inductances. The calculated values agree with the measurements within the experimental error. The material presented can be proposed to the students as a laboratory project. (Author) 7 refs

  15. Stability analysis of high temperature superconducting coil in liquid hydrogen

    International Nuclear Information System (INIS)

    Nakayama, T.; Yagai, T.; Tsuda, M.; Hamajima, T.

    2007-01-01

    Recently, it is expected that hydrogen plays an important role in energy source including electric power in near future. Liquid hydrogen has high potential for cooling down superconducting coil wound with high temperature superconductors (HTS), such as BSCCO, YBCO. In this paper, we study stabilities of the coils wound with BSCCO tapes, which are immersed in the liquid hydrogen, and compare stability results with those cooled by liquid helium. We treat a minimum propagation zone (MPZ) theory to evaluate the coil stability considering boiling heat flux of the liquid hydrogen, and specific heat, heat conduction and resistivity of HTS materials as a function of temperature. It is found that the coil cooled by the liquid hydrogen has higher stability margin than that cooled by the liquid helium. We compare the stability margins of both coils wound with Bi-2223/Ag tape and Bi-2212/Ag tape in liquid hydrogen. As a result, it is found that the stability of Bi-2212 coil is equivalent to that of Bi-2223 coil in low and high magnetic field, while the maximum current of Bi-2212 coil exceeds a little bit that of Bi-2223 coil in both magnetic fields

  16. Finite element modeling of TFTR poloidal field coils

    International Nuclear Information System (INIS)

    Baumgartner, J.A.; O'Toole, J.A.

    1986-01-01

    The Tokamak Fusion Test Reactor (TFTR) Poloidal Field (PF) coils were originally analyzed to TFTR design conditions. The coils have been reanalyzed by PPPL and Grumman to determine operating limits under as-built conditions. Critical stress levels, based upon data obtained from the reanalysis of each PF coil, are needed for input to the TFTR simulation code algorithms. The primary objective regarding structural integrity has been to ascertain the magnitude and location of critical internal stresses in each PF coil due to various combinations of electromagnetic and thermally induced loads. For each PF coil, a global finite element model (FEM) of a coil sector is being analyzed to obtain the basic coil internal loads and displacements. Subsequent fine mesh local models of the coil lead stem and lead spur regions produce the magnitudes and locations of peak stresses. Each copper turn and its surrounding insulation are modeled using solid finite elements. The corresponding electromagnetic and thermal analyses are similarly modeled. A series of test beams were developed to determine the best combination of MSC/NASTRAN-type finite elements for use in PF coil analysis. The results of this analysis compare favorably with those obtained by the earlier analysis which was limited in scope

  17. Stiffness control of a nylon twisted coiled actuator for use in mechatronic rehabilitation devices.

    Science.gov (United States)

    Edmonds, Brandon P R; Trejos, Ana Luisa

    2017-07-01

    Mechatronic rehabilitation devices, especially wearables, have been researched extensively and proven to be promising additions to physical therapy, but most designs utilize traditional actuators providing unnatural, robot-like movements. Therefore, many researchers have focused on the development of actuators that mimic biological properties to provide patients with improved results, safety, and comfort. Recently, a twisted-coiled actuator (TCA) made from nylon thread has been found to possess many of these important properties when heated, such as variable stiffness, flexibility, and high power density. So far, TCAs have been characterized in controlled environments to define their fundamental properties under simple loading configurations. However, for an actuator like this to be implemented in a biomimetic design such as an exoskeleton, it needs to be characterized and controlled as a biological muscle. One major control law that natural muscles exhibit is stiffness control, allowing humans to passively avoid injury from external forces, or move the limbs in a controlled or high impact motion. This type of control is created by the antagonistic muscle arrangement. In this paper, an antagonistic apparatus was developed to model the TCAs from a biological standpoint, the stiffness was characterized with respect to the TCA temperature, and a fully functional stiffness and position controller was implemented with an incorporated TCA thermal model. The stiffness was found to have a linear relationship to the TCA temperatures (R 2 =0.95). The controller performed with a stiffness accuracy of 98.95% and a position accuracy of 92.7%. A final trial with varying continuous position input and varying stepped stiffness input exhibited position control with R 2 =0.9638.

  18. Material focus

    DEFF Research Database (Denmark)

    Sokoler, Tomas; Vallgårda, Anna K. A.

    2009-01-01

    In this paper we build on the notion of computational composites, which hold a material perspective on computational technology. We argue that a focus on the material aspects of the technology could be a fruitful approach to achieve new expressions and to gain a new view on the technology's role...... in design. We study two of the computer's material properties: computed causality and connectability and through developing two computational composites that utilize these properties we begin to explore their potential expressions....

  19. Characteristics of parallel reverse coil inductors with different current ratio in coils used for melting in a suspension state

    International Nuclear Information System (INIS)

    Fogel', A.A.; Sidorova, T.A.; Smirnov, V.V.; Mezdrogina, M.M.

    1975-01-01

    The paper studies the effect of the ratio of the currents in the coils of an inductor with a parallel-switched ''reverse coil'', where the ratio of the current in the upper coil to that in the lower coil is 0.72. A region of stable dependence of liquid niobium characterized by upper and lower limits has been found. The maximum permissible volume of liquid niobium increases as the ratio of current in the upper coil to current in the lower coil decreases. The temperature dependences of niobium on the voltage in the inductor have been derived. Experiments have shown that the greater the capillary constant of niobium, the larger the region of stable dependence of liquid niobium, the larger the range of possible temperature regulation and the larger the maximum permissible volume. (N.K.)

  20. Mathematical model to determine the dimensions of superconducting cylindrical coils with a given central field – the case study for MgB{sub 2} conductors with isotropic I{sub c}(B) characteristic

    Energy Technology Data Exchange (ETDEWEB)

    Pitel, Jozef, E-mail: jozef.pitel@savba.sk [Institute of Electrical Engineering, Slovak Academy of Sciences, Dúbravská 9, 841 04 Bratislava (Slovakia); Melišek, Tibor [Institute of Electrical Engineering, Slovak Academy of Sciences, Dúbravská 9, 841 04 Bratislava (Slovakia); Tropeano, Matteo; Nardelli, Davide; Tumino, Andrea [Columbus Superconductors, Via delle Terre Rosse 30, I-16133 Genova (Italy)

    2016-08-15

    field in the winding. An influence of the safety coefficient in operating current on coil dimensions and other above mentioned parameters is studied as well. Finally, we compare the coil dimensions, overall conductor length as well as coil critical current and maximum field in the winding if the value of required central field changes between 1 and 3 T.