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Sample records for finnish hnpcc kindreds

  1. Nuclear Pedigree Criteria of Suspected HNPCC

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    Kładny Józef

    2003-01-01

    Full Text Available Abstract The criteria for the diagnosis of HNPCC established by the ICG-HNPCC are very restrictive as they do not allow for the diagnosis of a large number of "suspected HNPCC" cases - these are families which do no fulfill the strict diagnostic "Amsterdam criteria", but do present with several pedigree and clinical features characteristic for HNPCC. Several series of families suspected of harboring germline mutations in DNA mismatch repair genes have been studied for germline changes in DNA mismatch repair genes and a mutation rate of somewhere between 8-60% was found. Therefore a subgroup of members of the ICG-HNPCC has been working on pedigree/clinical diagnostic criteria for suspected HNPCC. Materials and methods Part I The study was based on two series of colorectal cancer (CRC cases: 1 HNPCC - this group comprised 190 patients affected by CRC from randomly selected families which fulfilled the Amsterdam II criteria registered in Düsseldorf, Germany (102 cases of CRC, Denmark (18 CRCs, Leiden, Holland (23 CRCs and Szczecin, Poland (47 CRCs. 2 Consecutive CRCs - this group comprised 629 (78.0% of 806 individuals with CRC diagnosed in 1991-1997 in the city of Szczecin (ca. 400,000 of inhabitants, Poland. Nuclear pedigrees in both groups were compared for frequency of occurrence of clinical features, that have been shown to be associated with HNPCC. Part II 52 consecutive CRC cases from Szczecin, matching the criteria recognized in part I as appropriate for diagnosis of cases "suspected of HNPCC" were studied for the occurrence of germline hMSH2/hMLH1 constitutional mutations using "exon by exon" sequencing. Results The combination of features - i.e. the occurrence of an HNPCC associated cancer (CRC or cancer of the endometrium, small bowel or urinary tract in a 1st degree relative of a CRC patient; at least one of the patients being diagnosed under age of 50 - appeared to be strongly associated to HNPCC with an OR - 161. Constitutional

  2. HNPCC: Six new pathogenic mutations

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    Epplen Joerg T

    2004-06-01

    Full Text Available Abstract Background Hereditary non-polyposis colorectal cancer (HNPCC is an autosomal dominant disease with a high risk for colorectal and endometrial cancer caused by germline mutations in DNA mismatch-repair genes (MMR. HNPCC accounts for approximately 2 to 5% of all colorectal cancers. Here we present 6 novel mutations in the DNA mismatch-repair genes MLH1, MSH2 and MSH6. Methods Patients with clinical diagnosis of HNPCC were counselled. Tumor specimen were analysed for microsatellite instability and immunohistochemistry for MLH1, MSH2 and MSH6 protein was performed. If one of these proteins was not detectable in the tumor mutation analysis of the corresponding gene was carried out. Results We identified 6 frameshift mutations (2 in MLH1, 3 in MSH2, 1 in MSH6 resulting in a premature stop: two mutations in MLH1 (c.2198_2199insAACA [p.N733fsX745], c.2076_2077delTG [p.G693fsX702], three mutations in MSH2 (c.810_811delGT [p.C271fsX282], c.763_766delAGTGinsTT [p.F255fsX282], c.873_876delGACT [p.L292fsX298] and one mutation in MSH6 (c.1421_1422dupTG [p.C475fsX480]. All six tumors tested for microsatellite instability showed high levels of microsatellite instability (MSI-H. Conclusions HNPCC in families with MSH6 germline mutations may show an age of onset that is comparable to this of patients with MLH1 and MSH2 mutations.

  3. Molecular aspects of HNPCC and identification of mutation carriers

    NARCIS (Netherlands)

    Niessen, Renée Cecil

    2007-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC) - also referred to as Lynch syndrome - is an autosomal dominantly inherited disorder of cancer susceptibility with high penetrance (80-85%). It is one of the most common inherited cancer syndromes identified in humans so far. In typical HNPCC

  4. Deletion Mutations in an Australian Series of HNPCC Patients

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    McPhillips Mary

    2005-11-01

    Full Text Available Abstract Hereditary non polyposis colorectal cancer (HNPCC is characterized by the presence of early onset colorectal cancer and other epithelial malignancies. The genetic basis of HNPCC is a deficiency in DNA mismatch repair, which manifests itself as DNA microsatellite instability in tumours. There are four genes involved in DNA mismatch repair that have been linked to HNPCC; these include hMSH2, hMLH1, hMSH6 and hPMS2. Of these four genes hMLH1 and hMSH2 account for the majority of families diagnosed with the disease. Notwithstanding, up to 40 percent of families do not appear to harbour a change in either hMSH2 or hMLH1 that can be detected using standard screening procedures such as direct DNA sequencing or a variety of methods all based on a heteroduplex analysis. In this report we have screened a series of 118 probands that all have the clinical diagnosis of HNPCC for medium to large deletions by the Multiplex Ligation-Dependent Probe Amplification assay (MLPA to determine the frequency of this type of mutation. The results indicate that a significant proportion of Australian HNPCC patients harbour deletion or duplication mutations primarily in hMSH2 but also in hMLH1.

  5. Functional analysis of HNPCC-related missense mutations in MSH2

    DEFF Research Database (Denmark)

    Lützen, Anne; de Wind, Niels; Georgijevic, Dubravka

    2008-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC) is associated with germline mutations in the human DNA mismatch repair (MMR) genes, most frequently MSH2 and MLH1. The majority of HNPCC mutations cause truncations and thus loss of function of the affected polypeptide. However, a significant...

  6. Hereditary non-polyposis colorectal cancer: clinical features and survival. Results from the Danish HNPCC register

    DEFF Research Database (Denmark)

    Myrhøj, T; Bisgaard, M L; Bernstein, Inge Thomsen

    1997-01-01

    BACKGROUND: Hereditary non-polyposis colorectal cancer (HNPCC) is a dominantly inherited syndrome characterized by the development of colorectal cancer (CRC) and other carcinomas. Our aim was to evaluate tumour parameters and survival in HNPCC. METHODS: One hundred and eight Danish HNPCC patients...... were compared with 870 patients with sporadic colorectal cancer. RESULTS: The median age at CRC diagnosis was 41 years in the HNPCC group. HNPCC patients had significantly more carcinomas located to the right colon (68% against 49% in controls), more synchromous tumours (7% versus 1%), more...

  7. Identification of HNPCC by Molecular Analysis of Colorectal and Endometrial Tumors

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    H. F. A. Vasen

    2004-01-01

    Full Text Available Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome is a dominantly inherited syndrome characterized by the development of colorectal cancer, endometrial cancer and other cancers and the presence of microsatellite instability (MSI in tumors. The Bethesda guidelines have been proposed for the identification of families suspected of HNPCC that require further molecular analysis. We have evaluated the yield of MSI-analysis in a large series of Dutch families suspected of HNPCC. We also analysed whether the loss of mismatch repair (MMR protein detected by immunohistochemistry (IHC of colorectal cancer (CRC and endometrial cancer correlated with the presence of MSI and/or a MMR gene mutation. The results showed that the Bethesda criteria with a few modifications are appropriate to identify families eligible for genetic testing. In addition, we found that MSI and IHC-analysis of CRC using antibodies against MLH1, MSH2, MSH6 and PMS2 proteins are equally effective for identifying carriers of the known MMR gene defects. However, as long as the role of other putative MMR genes in hereditary CRC has not been elucidated, IHC-analysis cannot completely replace MSI. For this reason, we prefer MSI-analysis as first step in families suspected of HNPCC. On the other hand, in families fulfilling the revised Amsterdam criteria in which the probability of detecting a mutation is relatively high, we would recommend IHC as first diagnostic step because the result might predict the specific underlying MMR gene mutation. MSI or IHC-analysis of endometrial cancer alone was found to be less sensitive compared with these tests performed in colorectal cancer. Therefore, probably the best approach in the analysis of this cancer is to perform both techniques. The identification of HNPCC is important as it makes it possible to target effective preventative measures. Our studies showed that MSI and IHC analysis of colorectal and endometrial cancer, are reliable

  8. Functional analysis of HNPCC-related missense mutations in MSH2

    International Nuclear Information System (INIS)

    Luetzen, Anne; Wind, Niels de; Georgijevic, Dubravka; Nielsen, Finn Cilius; Rasmussen, Lene Juel

    2008-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC) is associated with germline mutations in the human DNA mismatch repair (MMR) genes, most frequently MSH2 and MLH1. The majority of HNPCC mutations cause truncations and thus loss of function of the affected polypeptide. However, a significant proportion of MMR mutations found in HNPCC patients are single amino acid substitutions and the functional consequences of many of these mutations in DNA repair are unclear. We have examined the consequences of seven MSH2 missense mutations found in HNPCC families by testing the MSH2 mutant proteins in functional assays as well as by generating equivalent missense mutations in Escherichia coli MutS and analyzing the phenotypes of these mutants. Here we show that two mutant proteins, MSH2-P622L and MSH2-C697F confer multiple biochemical defects, namely in mismatch binding, in vivo interaction with MSH6 and EXO1, and in nuclear localization in the cell. Mutation G674R, located in the ATP-binding region of MSH2, appears to confer resistance to ATP-dependent mismatch release. Mutations D167H and H639R show reduced mismatch binding. Results of in vivo experiments in E. coli with MutS mutants show that one additional mutant, equivalent of MSH2-A834T that do not show any defects in MSH2 assays, is repair deficient. In conclusion, all mutant proteins (except for MSH2-A305T) have defects; either in mismatch binding, ATP-release, mismatch repair activity, subcellular localization or protein-protein interactions

  9. Functional analysis of HNPCC-related missense mutations in MSH2

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    Luetzen, Anne [Department of Science, Systems and Models, Roskilde University, DK-4000 Roskilde (Denmark); Wind, Niels de; Georgijevic, Dubravka [Department of Toxicogenetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden (Netherlands); Nielsen, Finn Cilius [Department of Clinical Biochemistry, Rigshospitalet, DK-2100 Copenhagen (Denmark); Rasmussen, Lene Juel [Department of Science, Systems and Models, Roskilde University, DK-4000 Roskilde (Denmark)], E-mail: ljr@ruc.dk

    2008-10-14

    Hereditary nonpolyposis colorectal cancer (HNPCC) is associated with germline mutations in the human DNA mismatch repair (MMR) genes, most frequently MSH2 and MLH1. The majority of HNPCC mutations cause truncations and thus loss of function of the affected polypeptide. However, a significant proportion of MMR mutations found in HNPCC patients are single amino acid substitutions and the functional consequences of many of these mutations in DNA repair are unclear. We have examined the consequences of seven MSH2 missense mutations found in HNPCC families by testing the MSH2 mutant proteins in functional assays as well as by generating equivalent missense mutations in Escherichia coli MutS and analyzing the phenotypes of these mutants. Here we show that two mutant proteins, MSH2-P622L and MSH2-C697F confer multiple biochemical defects, namely in mismatch binding, in vivo interaction with MSH6 and EXO1, and in nuclear localization in the cell. Mutation G674R, located in the ATP-binding region of MSH2, appears to confer resistance to ATP-dependent mismatch release. Mutations D167H and H639R show reduced mismatch binding. Results of in vivo experiments in E. coli with MutS mutants show that one additional mutant, equivalent of MSH2-A834T that do not show any defects in MSH2 assays, is repair deficient. In conclusion, all mutant proteins (except for MSH2-A305T) have defects; either in mismatch binding, ATP-release, mismatch repair activity, subcellular localization or protein-protein interactions.

  10. Survey of HNPCC Management Analysis of Responses from 18 International Cancer Centres

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    Chow Elizabeth

    2005-10-01

    Full Text Available Abstract Eighteen international cancer centres responded to a questionnaire designed to determine clinic practices regarding the management of Hereditary Non-Polyposis Colorectal Cancer (HNPCC. Areas covered include definition, clinical intakes, pre-genetic testing for microsatellite instability (MSI or expression of mismatch repair (MMR genes by immunohistochemistry (IHC, mutational analysis, consent practices, counselling, surveillance planning, and surgical decision making. In the absence of a firm evidence base, some management practices were variable, with local access to funding and other resources being influential. More consistent responses were evident for management practices with a stronger evidence base from previous clinical research. This document provides important information to guide the management of HNPCC patients, allow comparisons to be made between the approaches of various clinics to HNPCC families, and define management issues that need to be addressed in clinical research.

  11. Biomedical informatics as support to individual healthcare in hereditary colon cancer: the Danish HNPCC system

    DEFF Research Database (Denmark)

    Bernstein, Inge Thomsen; Larsen, K.L.; Timshel, Susanne

    2011-01-01

    The Danish HNPCC register is a publically financed national database. The register gathers epidemiological and genomic data in HNPCC families to improve prognosis by screening and identifying family members at risk. Diagnostic data are generated throughout the country and collected over several d...

  12. MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC

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    Annegret Müller

    2004-01-01

    Full Text Available Genomic instability at simple repeated sequences, termed microsatellite instability (MSI, plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC more than 90% of cases show MSI, whereas only 10–15% of sporadic colorectal cancers do so. Thus, microsatellite analysis is commonly used as the first diagnostic screening test for HNPCC. In 1997, an international collaborative workshop sponsored by the National Cancer Institute (NCI proposed a set of guidelines for MSI-testing to improve reliability and reproducibility of the analysis as well to allow comparisons between different studies and different laboratories. In this review we assess the value of current protocols forMSI-testing and discuss some diagnostic pitfalls. Our findings support continued use of the MSI marker panel recommended in 1997. Additionally, MSI-testing should be improved by use of microdissection, which helps to identify additional patients with MSI due to enrichment of tumor cells and therefore increased sensitivity. In our view, immunohistochemical staining for mismatch repair protein expression is not a substitute for MSI-analysis but complements MSI screening and helps direct further testing. In summary, MSI-analysis is a highly sensitive and reliable screening method for HNPCC, that requires a well-equipped laboratory as well as an experienced pathologist. Integration of family history and histo-pathological features is also critical.

  13. HISTORIA DEL CÁNCER COLORRECTAL HEREDITARIO NO POLIPÓSICO (HNPCC

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    Patrick M Lynch, JD, MD

    2017-07-01

    Full Text Available Cáncer colorrectal No Poliposo Hereditario (HNPCC or “Síndrome de Lynch”, implica variantes patogénicas en los genes de reparación del mal pareamiento de bases del ADN (MMR, es la condición hereditaria más frecuente que predispone a adenomas colorrectales y cáncer colorrectal. En esta revisión se describe la historia de HNPCC, desde los primeros casos clínicos, la información clínica más sistemática, los criterios clínicos y finalmente, al descubrimiento de los propios genes MMR en 1993, incluidas las características claves de la inestabilidad de los microsatélites (MSI. este papel central del análisis de los microsatélites de los cánceres colorrectales implica una tendencia creciente hacia la “prueba universal” para evidenciar la MSI, ya sea por métodos de PCR o por inmunohistoquímica (IHQ. Aunque si bien, la prueba universal no ha sido completamente adoptada alrededor del mundo, nosotros ya estamos evolucionando hacia uso más rutinario de “paneles” de múltiples genes para la detección de mutaciones de línea germinal en genes MMR. Bajo estas circunstancias, uno puede razonablemente preguntarse si la comprensión del desarrollo histórico de las características clínicas de HNPCC es incluso relevante. Como este artículo espera demostrar una apreciación del escenario del HNPCC, ésta no sería completa sin una perspectiva histórica, incluyendo el papel importante del Dr. Henry Lynch sobre toda una vida de trabajo en este campo.

  14. The survival of patients with Stage III Colon Cancer is improved in HNPCC compared with sporadic cases. A Danish registry based study

    DEFF Research Database (Denmark)

    Brixen, Line Merrild; Bernstein, Inge Thomsen; Bülow, Steffen

    2013-01-01

    AIM: Patients with hereditary non-polyposis colorectal cancer (HNPCC) seem to have a better prognosis than those with sporadic colon cancer (CC)s. The aim was to compare survival after stage III CC in patients with HNPCC with those having sporadic CC. METHOD: 230 patients with hereditary cancer...... from The Danish HNPCC-Register and 3557 patients with sporadic CC from The Danish Colorectal Cancer Database, diagnosed during May 2001-December 2008 were included. HNPCC patients were classified according to Mismatch Repair mutation status and family pedigree. Sporadic cases had no known family...... history of cancer. Patient characteristics, geographic differences and survival data were analyzed. RESULTS: The overall survival (OS) was better in HNPCC patients compared to sporadic CC after stratification for sex and age (p=0.02; CI 1.04-1.7). The 5-year survival was 70% in HNPCC patients compared...

  15. Psychological distress in women at risk of hereditary breast/ovarian or HNPCC cancers in the absence of demonstrated mutations.

    Science.gov (United States)

    Geirdal, Amy Østertun; Reichelt, Jon G; Dahl, Alv A; Heimdal, Ketil; Maehle, Lovise; Stormorken, Astrid; Møller, Pål

    2005-01-01

    To examine psychological distress in women at risk of familial breast-ovarian cancer (FBOC) or hereditary non-polyposis colorectal cancer (HNPCC) with absence of demonstrated mutations in the family (unknown mutation). Two-hundred and fifty three consecutive women at risk of FBOC and 77 at risk of HNPCC and with no present or past history of cancer. They were aware of their risk and had received genetic counseling. Comparisons were made between these two groups, normal controls, and women who were identified to be BRCA1 mutation carriers. The questionnaires Beck Hopelessness Scale (BHS), General Health Questionnaire (GHQ-28), Hospital Anxiety and Depression Scale (HADS) and Impact of Event Scale (IES) were employed to assess psychological distress. No significant differences concerning psychological distress were observed between women with FBOC and women with HNPCC. Compared to mutation carriers for BRCA1, the level of anxiety and depression was significantly higher in the FBOC group with absence of demonstrated mutation. Compared to normal controls, the level of anxiety was higher, while the level of depression was lower in the groups with unknown mutation. Women in the absence of demonstrated mutations have higher anxiety and depression levels than women with known mutation-carrier status. Access to genetic testing may be of psychologically benefit to women at risk for FBOC or HNPCC.

  16. Target gene analyses of 39 amelogenesis imperfecta kindreds

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    Chan, Hui-Chen; Estrella, Ninna M. R. P.; Milkovich, Rachel N.; Kim, Jung-Wook; Simmer, James P.; Hu, Jan C-C.

    2012-01-01

    Previously, mutational analyses identified six disease-causing mutations in 24 amelogenesis imperfecta (AI) kindreds. We have since expanded the number of AI kindreds to 39, and performed mutation analyses covering the coding exons and adjoining intron sequences for the six proven AI candidate genes [amelogenin (AMELX), enamelin (ENAM), family with sequence similarity 83, member H (FAM83H), WD repeat containing domain 72 (WDR72), enamelysin (MMP20), and kallikrein-related peptidase 4 (KLK4)] and for ameloblastin (AMBN) (a suspected candidate gene). All four of the X-linked AI families (100%) had disease-causing mutations in AMELX, suggesting that AMELX is the only gene involved in the aetiology of X-linked AI. Eighteen families showed an autosomal-dominant pattern of inheritance. Disease-causing mutations were identified in 12 (67%): eight in FAM83H, and four in ENAM. No FAM83H coding-region or splice-junction mutations were identified in three probands with autosomal-dominant hypocalcification AI (ADHCAI), suggesting that a second gene may contribute to the aetiology of ADHCAI. Six families showed an autosomal-recessive pattern of inheritance, and disease-causing mutations were identified in three (50%): two in MMP20, and one in WDR72. No disease-causing mutations were found in 11 families with only one affected member. We conclude that mutation analyses of the current candidate genes for AI have about a 50% chance of identifying the disease-causing mutation in a given kindred. PMID:22243262

  17. Familial Breast and Bowel Cancer: Does It Exist?

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    Scott Rodney J

    2004-02-01

    Full Text Available Abstract There is much debate in the literature about familial predispositions to breast and bowel cancers yet little evidence is forthcoming to suggest that there are susceptibility genes that can account for such kindreds. Within the context of known susceptibility genes the most controversial syndrome is hereditary non-polyposis colorectal cancer (HNPCC. In HNPCC, breast cancers do occur yet their incidence overall is no different to that of the general population yet when studied at the molecular level these tumours often display DNA microsatellite instability suggesting that they do indeed belong to this genetic entity. In this review we examine the relationship between breast and bowel cancer and suggest a possible explanation for the diverse points of view described in the literature.

  18. Inheritance of proliferative breast disease in breast cancer kindreds

    International Nuclear Information System (INIS)

    Skolnick, M.H.; Cannon-Albright, L.A.; Goldgar, D.E.; Ward, J.H.; Marshall, C.J.; Schumann, G.B.; Hogle, H.; McWhorter, W.P.; Wright, E.C.; Tran, T.D.; Bishop, D.T.; Kushner, J.P.; Eyre, H.J.

    1990-01-01

    Previous studies have emphasized that genetic susceptibility to breast cancer is rare and is expressed primarily as premenopausal breast cancer, bilateral breast cancer, or both. Proliferative breast disease (PBD) is a significant risk factor for the development of breast cancer and appears to be a precursor lesion. PBD and breast cancer were studied in 103 women from 20 kindreds that were selected for the presence of two first degree relatives with breast cancer and in 31 control women. Physical examination, screening mammography, and four-quadrant fine-needle breast aspirates were performed. Cytologic analysis of breast aspirates revealed PBD in 35% of clinically normal female first degree relatives of breast cancer cases and in 13% of controls. Genetic analysis suggests that genetic susceptibility causes both PBD and breast cancer in these kindreds. This study supports the hypothesis that this susceptibility is responsible for a considerable portion of breast cancer, including unilateral and postmenopausal breast cancer

  19. How easily slaves are made : the presence of performativity in kindred by Octavia Butler

    OpenAIRE

    Lohne, Mari Sørhus

    2009-01-01

    In this thesis Octavia Butler’s Kindred is analysed with the use of Judith Butler’s theory of performativity. As the protagonist is a black woman, Kindred is especially helpful in order to understand the racializing norms Butler mentions in Bodies That Matter. The thesis analyses the transformation in the female protagonist Dana’s performativity in three stages: before the first time she is called to antebellum Maryland, while she is there, and after her final return home to California. By an...

  20. Molecular Analysis: Microsatellite Instability and Loss of Heterozygosity of Tumor Suppressor Gene in Hereditary Non-Polyposis Colorectal Cancer (HNPCC

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    Vesna Hadžiavdić

    2009-02-01

    Full Text Available HNPCC (Hereditary non-polyposis colorectal cancer development is caused by mutation of genes included in system of mismatch repair genes. The mutation exists at 60% of patients in hMSH2 gene, 30% in hMLH1 and 10% both in hPMS1and hPMS2 genes. RER+ exists in about 90% in hereditary non-polyposis colorectal cancer and about 15-28% in sporadic cancers.The purpose of the study was to determine highly sensitive microsatellite markers which can be fast and efficient way of microsatellite screening for detection of HNPCC patients. Moreover, we have analysed the loss of heterozygosity of tumour suppressor genes which could have the diagnostic value in detection of HPNCC patients.

  1. Prognostic factors for hereditary cancer distress six months after BRCA1/2 or HNPCC genetic susceptibility testing

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Brocker-Vriends, Annette H. J. T.; van Asperen, Christi J.; Sijmons, Rolf H.; Seynaeve, Caroline; Van Gool, Arthur R.; Klijn, Jan G. M.; Tibben, Aad

    This study explored predictors for hereditary cancer distress six months after genetic susceptibility testing for a known familial BRCA1/2 or HNPCC related mutation, in order to gain insight into aspects relevant for the identification of individuals needing additional psychosocial support. Coping,

  2. The Socio-Legal Analysis Of Sexual Harassment And Kindred ...

    African Journals Online (AJOL)

    The Socio-Legal Analysis Of Sexual Harassment And Kindred Offences. Adeniyi Olatunbosun. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/ifep.v12i1.23512 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for ...

  3. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Brocker-Vriends, Annette H. J. T.; van Asperen, Chhstl J.; Sijmons, Rolf H.; Seynaeve, Caroline; Van Gool, Arthur R.; Klijn, Jan G. M.; Riedijk, Samantha R.; van Dooren, Silvia; Tibben, Aad

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N = 271) rated the

  4. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Bröcker-Vriends, Annette H. J. T.; van Asperen, Christi J.; Sijmons, Rolf H.; Seynaeve, Caroline; van Gool, Arthur R.; Klijn, Jan G. M.; Riedijk, Samantha R.; van Dooren, Silvia; Tibben, Aad

    2007-01-01

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N=271) rated the

  5. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships.

    NARCIS (Netherlands)

    Oostrom, I.I.H. van; Meijers-Heijboer, H.; Duivenvoorden, H.J.; Brocker-Vriends, A.H.; Asperen, C.J. van; Sijmons, R.H.; Seynaeve, C.; Gool, A.R. van; Klijn, J.G.M.; Riedijk, S.R.; Dooren, S. van; Tibben, A.

    2007-01-01

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N=271) rated the

  6. Biomedical informatics as support to individual healthcare in hereditary colon cancer: the Danish HNPCC system.

    Science.gov (United States)

    Bernstein, Inge T; Lindorff-Larsen, Karen; Timshel, Susanne; Brandt, Carsten A; Dinesen, Birger; Fenger, Mogens; Gerdes, Anne-Marie; Iversen, Lene H; Madsen, Mogens R; Okkels, Henrik; Sunde, Lone; Rahr, Hans B; Wikman, Friedrick P; Rossing, Niels

    2011-05-01

    The Danish HNPCC register is a publically financed national database. The register gathers epidemiological and genomic data in HNPCC families to improve prognosis by screening and identifying family members at risk. Diagnostic data are generated throughout the country and collected over several decades. Until recently, paper-based reports were sent to the register and typed into the database. In the EC cofunded-INFOBIOMED network of excellence, the register was a model for electronic exchange of epidemiological and genomic data between diagnosing/treating departments and the central database. The aim of digitization was to optimize the organization of screening by facilitating combination of genotype-phenotype information, and to generate IT-tools sufficiently usable and generic to be implemented in other countries and for other oncogenetic diseases. The focus was on integration of heterogeneous data, elaboration, and dissemination of classification systems and development of communication standards. At the conclusion of the EU project in 2007 the system was implemented in 12 pilot departments. In the surgical departments this resulted in a 192% increase of reports to the database. Several gaps were identified: lack of standards for data to be exchanged, lack of local databases suitable for direct communication, reporting being time-consuming and dependent on interest and feedback. © 2011 Wiley-Liss, Inc.

  7. Gene expression signatures for colorectal cancer microsatellite status and HNPCC

    DEFF Research Database (Denmark)

    Kruhøffer, M; Jensen, J L; Laiho, P

    2005-01-01

    The majority of microsatellite instable (MSI) colorectal cancers are sporadic, but a subset belongs to the syndrome hereditary non-polyposis colorectal cancer (HNPCC). Microsatellite instability is caused by dysfunction of the mismatch repair (MMR) system that leads to a mutator phenotype, and MSI...... of 101 stage II and III colorectal cancers (34 MSI, 67 microsatellite stable (MSS)) using high-density oligonucleotide microarrays. From these data, we constructed a nine-gene signature capable of separating the mismatch repair proficient and deficient tumours. Subsequently, we demonstrated...... is correlated to prognosis and response to chemotherapy. Gene expression signatures as predictive markers are being developed for many cancers, and the identification of a signature for MMR deficiency would be of interest both clinically and biologically. To address this issue, we profiled the gene expression...

  8. The tumour spectrum in hereditary non-polyposis colorectal cancer: a study of 24 kindreds in the Netherlands

    NARCIS (Netherlands)

    Vasen, H. F.; Offerhaus, G. J.; den Hartog Jager, F. C.; Menko, F. H.; Nagengast, F. M.; Griffioen, G.; van Hogezand, R. B.; Heintz, A. P.

    1990-01-01

    The hereditary colonic cancer syndrome without polyposis, hereditary non-polyposis colorectal cancer (HNPCC), is usually divided into 2 main categories: hereditary site-specific colorectal cancer (Lynch syndrome I) and colorectal cancer in association with other forms of cancer (Lynch syndrome II).

  9. HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review

    Science.gov (United States)

    2003-01-01

    HNPCC (Lynch syndrome) is the most common form of hereditary colorectal cancer (CRC), wherein it accounts for between 2-7 percent of the total CRC burden. When considering the large number of extracolonic cancers integral to the syndrome, namely carcinoma of the endometrium, ovary, stomach, hepatobiliary system, pancreas, small bowel, brain tumors, and upper uroepithelial tract, these estimates of its frequency are likely to be conservative. The diagnosis is based upon its natural history in concert with a comprehensive cancer family history inclusive of all anatomic sites. In order for surveillance and management to be effective and, indeed, lifesaving, among these high-risk patients, the linchpin to cancer control would be the physician, who must be knowledgeable about hereditary cancer syndromes, their molecular and medical genetics, genetic counseling, and, most importantly, the natural history of the disorders, so that the entirety of this knowledge can be melded to highly-targeted management.

  10. Hereditary Colorectal Cancer (CRC Program in Latvia

    Directory of Open Access Journals (Sweden)

    Irmejs Arvids

    2003-12-01

    Full Text Available Abstract Introduction The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by these syndromes. Materials and methods From 02/1999-09/2002 in several hospitals in Latvia cancer family histories were collected from 865 patients with CRC. In families suspected of having a history consistent with a hereditary colorectal cancer syndrome, DNA testing for MLH1, MSH2 and MSH6 genes was performed. In addition immunohistochemical (IH examination of the normal and cancer tissue from large bowel tumors for MSH2 and MSH6 protein expression was performed prior to DNA analysis. Results From the 865 CRC cases only 3 (0.35% pedigrees fulfilled the Amsterdam II criteria of Hereditary Nonpolyposis Colorectal Cancer (HNPCC and 15 cases (1.73% were suspected of HNPCC. In 69 cases (8% with a cancer family aggregation (CFA were identified. Thus far 27 IH analyses have been performed and in 3 cancers homogenous lack of MSH2 or MSH6 protein expression was found. In one of these cases a mutation in MSH6 was identified. In 18 patients suspected of HNPCC or of matching the Amsterdam II criteria, denaturing high performance liquid chromatography (DHPLC followed by DNA sequencing of any heteroduplexes of the 35 exons comprising both MLH1 and MSH2 was performed revealing 3 mutations. For all of kindreds diagnosed definitively or with a high probability of being an HNPCC family appropriate recommendations concerning prophylactic measures, surveillance and treatment were provided in written form. Conclusions Existing pedigree/clinical data suggest that in Latvia the frequency of HNPCC is around 2% of consecutive colorectal cancer patients. It is crucial that genetic counseling is an integral part of cancer family syndrome management.

  11. A Dutch kindred with familial amyloidotic polyneuropathy associated with the transthyretin Cys 114 mutant

    NARCIS (Netherlands)

    Haagsma, EB; Post, JG; DeJager, AEJ; Nikkels, PGJ; Hamel, BCJ; Hazenberg, BPC

    A Dutch kindred with transthyretin Cys 114 related familial amyloidotic polyneuropathy is reported. The finding of early involvement of the heart is of great concern and of special relevance to the optimal timing for liver transplantation. To date, the variant had only been reported to be present in

  12. HNPCC (Lynch Syndrome: Differential Diagnosis, Molecular Genetics and Management - a Review

    Directory of Open Access Journals (Sweden)

    Lynch Henry T

    2003-12-01

    Full Text Available Abstract HNPCC (Lynch syndrome is the most common form of hereditary colorectal cancer (CRC, wherein it accounts for between 2-7 percent of the total CRC burden. When considering the large number of extracolonic cancers integral to the syndrome, namely carcinoma of the endometrium, ovary, stomach, hepatobiliary system, pancreas, small bowel, brain tumors, and upper uroepithelial tract, these estimates of its frequency are likely to be conservative. The diagnosis is based upon its natural history in concert with a comprehensive cancer family history inclusive of all anatomic sites. In order for surveillance and management to be effective and, indeed, lifesaving, among these high-risk patients, the linchpin to cancer control would be the physician, who must be knowledgeable about hereditary cancer syndromes, their molecular and medical genetics, genetic counseling, and, most importantly, the natural history of the disorders, so that the entirety of this knowledge can be melded to highly-targeted management.

  13. Nephritogenic antigen determinants in epidermal and renal basement membranes of kindreds with Alport-type familial nephritis.

    Science.gov (United States)

    Kashtan, C; Fish, A J; Kleppel, M; Yoshioka, K; Michael, A F

    1986-10-01

    We probed epidermal basement membranes (EBM) of acid-urea denatured skin from members of kindreds with Alport-type familial nephritis (FN) for the presence of antigens reactive with Goodpasture sera (GPS) and serum (FNS) from an Alport patient who developed anti-glomerular basement membrane (GBM) nephritis in a renal allograft. By immunoblotting, GPS reacted primarily with the 28,000 molecular weight (mol wt) monomer but also the 24,000 mol wt and 26,000 mol wt monomers of the noncollagenous globular domain (NC1) of type IV collagen from normal human GBM, while FNS identified only the 26,000-mol wt monomer. FNS reacted with EBM of 12 controls and nine unaffected male kindred members but not EBM of eight affected males. Five affected females exhibited interrupted reactivity of FNS with EBM. GPS showed variable reactivity with EBM and was not discriminating with respect to Alport-type FN. FNS did not stain renal basement members of five affected males. However, the EBM, tubular basement membrane, and Bowman's capsules of affected males contained antigens reactive with GPS. These immunochemical studies suggest that the FNS antigen is distinct from Goodpasture antigen(s). The expression of FNS antigen located on the NC1 domain of type IV collagen is altered in basement membranes of patients with Alport-type FN, and the distribution of this antigenic anomaly within kindreds suggests X-linked dominant transmission of a defective gene.

  14. Finnish Kullervo and chinese martial arts stories

    OpenAIRE

    Chen, Chapmen

    2006-01-01

    Introduction: There are many important Finnish plays but, due to language barrier, Finnish drama is seldom exported, particularly to Hong Kong and China.. Objective: To find out differences in mentality between the Finnish and Chinese peoples by comparing the partially localized Chinese translation of Aleksis Kivi’s tragedy, Kullervo, with genuine Chinese martial arts literature. Methodology: 1. Chapman Chen has translated the Finnish classic, Kullervo, directly from Finnish...

  15. At the Roots of Finnish Elementary Education – How Were Children Raised in the First Finnish Elementary Schools?

    Directory of Open Access Journals (Sweden)

    Satu UUSIAUTTI

    2013-03-01

    Full Text Available This study dissects the history of Finnish elementary education and the way children were raised during the initial phase of Finnish education in the 18th century. The development of Finnish education was studied through contemporary decrees and laws and studies of Finnish school history. The preliminary aim was to focus on the principles and practices of raising children in Finnish schools. This study focuses on (1 describing the birth, goals, and practices of Finnish elementary education and development toward compulsory education, (2 describing the way children were raised toward the contemporary goals, and (3 dissecting the connection between teacher training and the goals of raising children in Finnish schools. All these viewpoints are discussed from the viewpoint of how the aspirations and objectives were realized and implemented in practice in raising children. As a conclusion, we discuss the influence of the past in today’s educational practices.

  16. At the Roots of Finnish Elementary Education –How Were Children Raised in the First Finnish Elementary Schools?

    Directory of Open Access Journals (Sweden)

    Satu UUSIAUTTI

    2013-03-01

    Full Text Available This study dissects the history of Finnish elementary education and the way children were raised during the initial phase of Finnish education in the 18th century. The development of Finnish education was studied through contemporary decrees and laws and studies of Finnish school history. The preliminary aim was to focus on the principles and practices of raising children in Finnish schools. This study focuses on (1 describing the birth, goals, and practices of Finnish elementary education and development toward compulsory education, (2 describing the way children were raised toward the contemporary goals, and (3 dissecting the connection between teacher training and the goals of raising children in Finnish schools. All these viewpoints are discussed from the viewpoint of how the aspirations and objectives were realized and implemented in practice in raising children. As a conclusion, we discuss the influence of the past in today’s educational practices.

  17. A systematic search for linkage with nonsyndromic recessive deafness in two large Middle Eastern inbred kindreds excludes more than 30% of the genome

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, S.; Korostishevsky, M. [Sackler Faculty of Medicine, Ramat-Aviv (Israel); Frydman, M. [Haim Sheba Medical Center, Tel-Hashomer (Israel)] [and others

    1994-09-01

    It has been estimated that as many as 35 loci may individually cause autosomal recessive non-syndromic deafness. The extreme genetic heterogeneity, limited clinical differentiation and phenotypic assortative mating in many western countries make many families unsuitable for genetic linkage studies. Recently the first of those loci was mapped (to 13q) in two consanguineous families from northern Tunisia. We are studying two large highly consanguineous Middle Eastern kindreds (a total of 26 deaf in 98 sampled individuals). Examination in each family showed no evidence of clinical heterogeneity and indicated an uncomplicated profound bilateral sensorineural deafness. We have been able to exclude the 13q locus as the cause of deafness in each kindred and have also excluded such `candidate` loci as regions as those causing Usher`s syndrome type 1 (11q13)(11p), Usher`s syndrome type II (1q32-q41), Waardenburg syndrome type I (2q37), branchio-oto-renal syndrome (8q12-q13), Monge`s deafness (5q31), and Treacher Collins syndrome (5q31.3-q33.3). To date, no lod scores greater than 1 have been obtained in either kindred using 150 RFLT`s, VNTR`s and highly polymorphic microsatellite markers (CA repeats and tetranucleotides). By Morton`s criterion a minimum of 30% of the autosomal genome can be excluded for each kindred separately.

  18. Finnish Bioenergy Association - Finbio

    International Nuclear Information System (INIS)

    Sopo, R.

    1999-01-01

    The Finnish Bioenergy Association, was founded in November 1991 in the city of Jyvaeskylae. In November 1996, the membership of FINBIO consisted of 17 contributing collective members and 75 individual members. Members of the organization include e.g. the Association of Finnish Peat Industries, Wood Energy Association and Finnish Biogas Centre, all of which represent specific bioenergy fields in Finland. The Finnish Bioenergy Association is a private, non-profit organization the objectives of which are to promote and develop harvesting, transportation and processing of biofuels and other biomass (wood-based biofuels, non-food crops, peat, biowaste); to promote the use of biomass in energy production and in other applications, in accordance with environmentally sound and sustainable development. The objectives of FINBIO is to promote the production and application of all forms of bioenergy in Finland. FINBIO acts as a coordinator for AEBIOM (the European Biomass Association) and its member associations, as well as for other international bioenergy-related organizations

  19. Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Brocker-Vriends, Annette H. J. T.; van Asperen, Christi J.; Sijmons, Rolf H.; Seynaeve, Caroline; Van Gool, Arthur R.; Klijn, Jan G. M.; Tibben, Aad

    Objective: To study differences between individuals opting for genetic cancer susceptibility testing of a known familial BRCA1/2 and HNPCC related germline mutation. Methods: Coping, illness perceptions, experiences with cancer in relatives and family system characteristics were assessed in 271

  20. The Finnish "social wilderness"

    Science.gov (United States)

    Ville Hallikainen

    2000-01-01

    The cultural roots and images of the Finnish wilderness lie in its use as a source of livelihood practiced in southern and central Finland during the Middle Ages. There are statutory wilderness areas in Finland, but Finnish people consider many other areas as wilderness. It is important for management of the areas, statutory wilderness areas and the other wilderness-...

  1. Finnish bioenergy research programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D. [VTT Energy, Jyvaeskylae (Finland)

    1996-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  2. Finnish bioenergy research programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D [VTT Energy, Jyvaeskylae (Finland)

    1997-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  3. Big data in Finnish financial services

    OpenAIRE

    Laurila, M. (Mikko)

    2017-01-01

    Abstract This thesis aims to explore the concept of big data, and create understanding of big data maturity in the Finnish financial services industry. The research questions of this thesis are “What kind of big data solutions are being implemented in the Finnish financial services sector?” and “Which factors impede faster implementation of big data solutions in the Finnish financial services sector?”. ...

  4. Finnish in America: Two Kinds of Finglish.

    Science.gov (United States)

    Karttunen, Frances; Moore, Kate

    The Finnish language spoken by Finns who emigrated to America is often called "Finglish;" two distinct varieties are discussed in this paper. American Finnish differs from native Finnish in its assimilation of a substantial number of loan words that augment and sometimes replace the original vocabulary. Many loan words deal with employment,…

  5. Speech perception and vocabulary growth: A longitudinal study of Finnish-Russian bilinguals and Finnish monolinguals from infancy to three years

    NARCIS (Netherlands)

    Silvén, M.; Voeten, M.J.M.; Kouvo, A.M.; Lundén, M.

    2014-01-01

    Growth modeling was applied to monolingual (N = 26) and bilingual (N = 28) word learning from 14 to 36 months. Level and growth rate of vocabulary were lower for Finnish-Russian bilinguals than for Finnish monolinguals. Processing of Finnish speech sounds at 7 but not at 11 months predicted level,

  6. Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associated highly-consanguineous families from Kuwait: emphasis on premarital genetic testing.

    Science.gov (United States)

    Marafie, Makia J; Al-Awadi, Sadiqa; Al-Mosawi, Fatemah; Elshafey, Alaa; Al-Ali, Waleed; Al-Mulla, Fahd

    2009-01-01

    Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) is one of the commonest cancer susceptibility syndromes. It is characterized by early onset colon cancer and a variety of extracolonic tumours. Germline mutations in the DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS1, and PMS2) are responsible for this disorder. Identifying an affected individual depends on the tumour histopathology, family history that fulfils the Amsterdam and/or Bethesda criteria, tumour immunohistochemistry, microsatellite instability, and finally molecular analysis of an affected member. It is a laborious, time consuming and expensive procedure, which needs the effort of a multi-disciplinary team. However, once the diagnosis is established and germline defect is identified, other high risk pre-symptomatic carriers could be offered intensive surveillance and management as a preventive measure against cancer development. Here, we present two large highly consanguineous HNPCC-families from Kuwait in whom a founder MSH2 mutation was identified. The relationship between this mutation and cancer expressivity in two large consanguineous families harbouring other genetic defects is discussed. Moreover, we shed light on the challenges pertaining to diagnosis, screening, premarital counselling of couples and prenatal diagnosis of offspring with biallelic MSH2 gene mutation.

  7. Association of Finnish Members of Parliament and Researchers: Social Democratic Parliamentary group MP K. Olin, Former Finnish MP M. Tiuri, Finnish Centre Party MP P. Vilkuna, Senior Assistant Professor I. Ruostetsaari and Finnish Parliament Committee of Future Researcher U. Gabrielsson at ATLAS experiment with P. Jenn, M. Nordberg and M. Kotamaki on 15 September 2006.

    CERN Document Server

    Maximilien Brice

    2006-01-01

    Association of Finnish Members of Parliament and Researchers: Social Democratic Parliamentary group MP K. Olin, Former Finnish MP M. Tiuri, Finnish Centre Party MP P. Vilkuna, Senior Assistant Professor I. Ruostetsaari and Finnish Parliament Committee of Future Researcher U. Gabrielsson at ATLAS experiment with P. Jenn, M. Nordberg and M. Kotamaki on 15 September 2006.

  8. Exporting Finnish teacher education: Transnational pressures on national models

    Directory of Open Access Journals (Sweden)

    Jennifer Chung

    2017-07-01

    Full Text Available This article analyses empirical data to assess the possible transfer of Finnish teacher education policy, and more specifically, the university training school, into another context. Transnational organisations increasingly pressure nation-states to carry out education policy change, especially due to dissatisfaction with international assessment outcomes. As a high performer in the Programme for International Student Assessment (PISA, administered by the Organisation for Economic Cooperation and Development (OECD, Finland has been at the centre of international attention. PISA revealed that the high quality of Finnish teachers contributes to the overall calibre of the country’s education system. Thus, Finnish teacher education has become a model for other education systems. This article uses empirical research to explore the export possibilities of the Finnish normaalikoulu, or university training school. It implements qualitative methodology, using semi-structured interviews with Finnish educationalists to explore the possible export of Finnish education, the implications in terms of policy transfer, and the migration of ideas, specifically the university-affiliated, teacher training school. The export and migration of Finnish education and its impact on education policy are discussed in this article, along with educational export’s position in transnational policy formation.

  9. LEAN thinking in Finnish healthcare.

    Science.gov (United States)

    Jorma, Tapani; Tiirinki, Hanna; Bloigu, Risto; Turkki, Leena

    2016-01-01

    Purpose - The purpose of this study is to evaluate how LEAN thinking is used as a management and development tool in the Finnish public healthcare system and what kind of outcomes have been achieved or expected by using it. The main focus is in managing and developing patient and treatment processes. Design/methodology/approach - A mixed-method approach incorporating the Webropol survey was used. Findings - LEAN is quite a new concept in Finnish public healthcare. It is mainly used as a development tool to seek financial savings and to improve the efficiency of patient processes, but has not yet been deeply implemented. However, the experiences from LEAN initiatives have been positive, and the methodology is already quite well-known. It can be concluded that, because of positive experiences from LEAN, the environment in Finnish healthcare is ready for the deeper implementation of LEAN. Originality/value - This paper evaluates the usage of LEAN thinking for the first time in the public healthcare system of Finland as a development tool and a management system. It highlights the implementation and achieved results of LEAN thinking when used in the healthcare environment. It also highlights the expectations for LEAN thinking in Finnish public healthcare.

  10. Bibliometric evaluation of Finnish astronomy

    OpenAIRE

    Isaksson, Eva

    2007-01-01

    Finnish astronomy publishing provides us with an interesting data sample. It is small but not too small: approximately one thousand articles have been published in a decade. There are only four astronomy institutes to be compared. An interesting paradox also emerges in the field: while Finnish science assessments usually value highly the impact of scientific publishing, no serious evaluations using real bibliometric data have been made. To remedy this, a comprehensive ten-year database of ref...

  11. Germline but macrophage-tropic CYBB mutations in kindreds with X-linked predisposition to tuberculous mycobacterial diseases

    OpenAIRE

    2011-01-01

    Abstract Germline mutations in the human CYBB gene, encoding the gp91phox subunit of the phagocyte NADPH oxidase, impair the respiratory burst of phagocytes and result in X-linked chronic granulomatous disease. We report two kindreds in which otherwise healthy male adults show X-linked recessive Mendelian susceptibility to mycobacterial diseases. These patients harbor mutations in CYBB that profoundly reduce the respiratory burst in monocyte-derived macrophages, but not in monocyte...

  12. Burnout among Finnish and Chinese university students.

    Science.gov (United States)

    Hernesniemi, Elina; Räty, Hannu; Kasanen, Kati; Cheng, Xuejiao; Hong, Jianzhong; Kuittinen, Matti

    2017-10-01

    In this study the levels of experienced burnout of Finnish and Chinese university students are compared using School Burnout Inventory (SBI). This study is motivated by earlier studies, which suggest that the level of student burnout is different in the culturally distinct Finnish and Chinese university systems, but which are based on different research instruments for the two groups. The sample studied consisted of 3,035 Finnish students and 2,309 Chinese students. Because of the cross-cultural nature of this study the level of structural equivalence of SBI between the cultural groups was examined and the effect of different response styles on the results was taken into account. Both standard and robust statistical methods were used for the analyses. The results showed that SBI with two extracted components is suitable for cross-cultural analysis between Finnish and Chinese university students. Virtually no difference was found in experienced overall burnout between the Finnish and Chinese students, which means that both university systems contain factors causing similar levels of student burnout. This study also verified that controlling for the response styles is important in cross-cultural studies as it was found to have a distinct effect on the results obtained from mean-level comparisons. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  13. Woolly hair, premature loss of teeth, nail dystrophy, acral hyperkeratosis and facial abnormalities: possible new syndrome in a Dutch kindred.

    NARCIS (Netherlands)

    Steensel, M.A.M. van; Koedam, M.I.; Swinkels, O.Q.J.; Rietveld, F.J.R.; Steijlen, P.M.

    2001-01-01

    We describe a Dutch kindred with a possibly novel dominant syndrome of premature loss of curly, brittle hair, premature loss of teeth due to caries, nail dystrophy and acral keratoderma. We discuss the possibility that this ectodermal dysplasia of group 1-2-3-4 is a variant of known disorders such

  14. Marketing communication in Finnish industrial companies

    OpenAIRE

    Vuorio, Mikko

    2010-01-01

    Marketing communication has a significant role for profitable businesses in industrial markets, and its role is only expected to rise in the future. Especially, integrated marketing communication (IMC) and customer-oriented approach are universally regarded fundamental developments in the field of marketing. Secondly, Finnish companies’ marketing competences are commonly considered insufficient in general. The purpose of this study was to describe how Finnish industrial companies execute t...

  15. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1993-06-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations, relating to nuclear and radiation safety, which the Finnish Centre for Radiation and Nuclear Safety considers significant. Also other events of general interest are reported. The reports also include a summary of the radiation safety of plant personnel and the environment, as well as tabulated data on the plants' production and load factors

  16. Evaluation of the Finnish CERN activities panel report

    CERN Document Server

    Paul, Peter; Juuti, Pauli; Kullander, Sven; Ikonen, Eeva; Maalampi, Jukka

    2001-01-01

    The Academy of Finland decided in November 2000 that Finnish CERN-activities should be evaluated. The first ten years of the Finnish membership in CERN have been successful. Also in the future, Finland has great opportunities and benefits of the collaboration with CERN. The Finnish presentations clearly show the rapid development in experimental physics since the joining of CERN. Still, Finland can be considered as a relatively young Member State in CERN, but one of the most dynamic new partners for CERN.

  17. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1993-03-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations, relating to nuclear and radiation safety, which the Finnish Centre for Radiation and Nuclear Safety considers safety significant. Also other events of general interest are reported. The reports also include a summary of the radiation safety of plant personnel and the environment, as well as tabulated data on the plants' production and load factors

  18. Finnish Teachers’ Ethical Sensitivity

    Directory of Open Access Journals (Sweden)

    Elina Kuusisto

    2012-01-01

    Full Text Available The study examined the ethical sensitivity of Finnish teachers (=864 using a 28-item Ethical Sensitivity Scale Questionnaire (ESSQ. The psychometric qualities of this instrument were analyzed, as were the differences in self-reported ethical sensitivity between practicing and student teachers and teachers of different subjects. The results showed that the psychometric qualities of the ESSQ were satisfactory and enabled the use of an explorative factor analysis. All Finnish teachers rated their level of ethical sensitivity as high, which indicates that they had internalized the ethical professionalism of teaching. However, practicing teachers’ assessments were higher than student teachers’. Moreover, science as a subject was associated with lower self-ratings of ethical sensitivity.

  19. Nephritogenic antigen determinants in epidermal and renal basement membranes of kindreds with Alport-type familial nephritis.

    OpenAIRE

    Kashtan, C; Fish, A J; Kleppel, M; Yoshioka, K; Michael, A F

    1986-01-01

    We probed epidermal basement membranes (EBM) of acid-urea denatured skin from members of kindreds with Alport-type familial nephritis (FN) for the presence of antigens reactive with Goodpasture sera (GPS) and serum (FNS) from an Alport patient who developed anti-glomerular basement membrane (GBM) nephritis in a renal allograft. By immunoblotting, GPS reacted primarily with the 28,000 molecular weight (mol wt) monomer but also the 24,000 mol wt and 26,000 mol wt monomers of the noncollagenous ...

  20. A new Finnish nuclear power unit

    International Nuclear Information System (INIS)

    2004-01-01

    In Finland, nuclear power is considered a natural part of a sustainable energy system. The Finnish Parliament has decided that development of nuclear power is consistent with the overall interests of society when climate issues, environmental targets, supply security and stable and competitive prices of electric power are considered as a whole. In 2002, the Finnish Parliament approved the Government's decision in principle to build a fifth nuclear power plant. The new project is the most advanced energy project in the Nordic countries with respect to the availability of energy free of carbon dioxide. The decision is also welcomed by the EU. The new reactor will be of the EPR (European Pressurized Water Reactor) type. In addition to supplying power to the Finnish industries, the plant is considered necessary if Finland is to comply with international conventions on CO 2 emissions

  1. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1994-06-01

    Quarterly reports on the operation of the Finnish NPPs describe nuclear and radiation safety related events and observations which the Finnish Centre for Radiation and Nuclear Safety considers significant. Safety improvements at the plants and general matters relating to the use of nuclear energy are also reported. A summary of the radiation safety of plant personnel and the environment, and tabulated data on the plants' production and load factors are also given. One event during the last quarter of 1993 was rated on the International Nuclear Event Scale (INES) as level 1. During this event at Loviisa 2, the secondary circuit emergency feedwater system was erroneously isolated from automatic start-up readiness. The error went unnoticed for 4.5 hours. During 1993 one level 2 incident and three level 1 incidents occurred at the Finnish NPPs. (8 figs., 4 tabs.)

  2. Piloting Snapchat for Finnish Defence Forces

    OpenAIRE

    Immonen, Helena

    2016-01-01

    This thesis is about piloting Snapchat for Finnish Defence Forces. The goals for the thesis are to find out how Snapchat can be used as part of Finnish Defence Forces’ social media communication and strategy. Conscripts are the most important target group for social media communication in the Defence Forces. Young conscripts are the main target group for Snapchat. This thesis is theoretically based on organizational communication, stakeholder communication and social media communicati...

  3. Various Portraits of Finnish Open University Students

    Science.gov (United States)

    Jauhiainen, Arto; Nori, Hanna; Alho-Malmelin, Marika

    2007-01-01

    This article describes and analyses the background and goals of students at the Finnish open university in the beginning of the twenty-first century. The material consists of statistics based on the student records of the Finnish open university in 2000 (n = 9080) and of the stories, educational autobiographies written by the adult learners (n =…

  4. Finnish participation in the European utility requirements work

    International Nuclear Information System (INIS)

    Patrakka, E.

    2000-01-01

    The Finnish participation in the EUR process started already in April 1994 when IVO (Imatran Voima Oy presently Fortum Oyj) and TVO (Teollisuuden Voima Oy) were asked to comment EUR Volume 1 and 2 Revision A in April 1994. A formal application for the Finnish membership in the EUR organisation was sent on 20 November 1995, and Finland was accepted as an associated member on the next day. The Finnish representatives in the various EUR bodies were appointed in March 1996, at which time the formal participation in these bodies commenced. On 7 November 1996, EUR Steering Committee approved a full membership of IVO and TVO that are joint EUR members representing Finland together. A major Finnish contribution was made in 1997 when IVO and TVO performed a comparison between the EUR document and YVL guides. The period of the Finnish membership has been characterised by the compilation of EUR Volume 3 subsets, in which process IVO/Fortum and TVO have been actively participating. From the Finnish point of view, the EUR work can also be seen as a part of getting prepared to proceed with a possible new NPP project. The EUR document is a substantial aid when preparing the technical specifications for a NPP bid inquiry. The information received in connection with the detailed assessment work for Volume 3 subsets is very valuable when considering the feasibility of NPP concepts. In addition. the experiences gained in the Volume 3 activities enable to develop even better requirements that are manifested by Revision C of Volumes 1 and 2. (author)

  5. Electricity prices in the Finnish retail market

    International Nuclear Information System (INIS)

    Lehto, Eero

    2011-01-01

    This study focuses, firstly, on the pricing of electricity in the Finnish retail market. In particular, the impact of the ownership structure on prices is tested empirically. Secondly, the influence of low-cost electricity sources on retail prices is considered. The question about whether the average fuel costs rather than the wholesale price determine the retail prices is thus addressed. The supply side behaviour characterised may explain the passivity of client activity in the seemingly competitive Finnish market. - Research highlights: → Ownership has a strong impact on retail prices in the Finnish electricity market. → Locally owned companies' rates are 5-15 per cent lower than investor owned companies' rates. → Own low cost acquisition of electricity helps local firms to keep prices at low levels.

  6. Ernst Mach and the Epistemological Ideas Specific for Finnish Science Education

    Science.gov (United States)

    Siemsen, Hayo

    2011-03-01

    Where does Finnish science education come from? Where will it go? The following outside view reflects on relations, which Finns consider "normal" (and thus unrecognizable in introspection) in science education. But what is "normal" in Finnish culture cannot be considered "normal" for science education in other cultures, for example in Germany. The following article will trace the central ideas, which had a larger influence in the development of this difference. The question is, if and why the Finnish uniqueness in the philosophy of science education is empirically important. This puts Finnish science education into the perspective of a more general epistemological debate around Ernst Mach's Erkenntnistheorie (a German term similar to the meaning of history and philosophy of science, though more general; literally translated "cognition/knowledge theory"). From this perspective, an outlook will be given on open questions within the epistemology of Finnish science education. Following such questions could lead to the adaptation of the "successful" ideas in Finnish science education (indicated by empirical studies, such as the OECD PISA study) as well as the further development of the central ideas of Finnish science education.

  7. Finnish Society of Soil Sciences

    Science.gov (United States)

    Rankinen, Katri; Hänninen, Pekka; Soinne, Helena; Leppälammi-Kujansuu, Jaana; Salo, Tapio; Pennanen, Taina

    2017-04-01

    In 1998 the organization of the International Union of Soil Sciences (IUSS) was renewed to better support national activities. That was also the new start in the operation of the Finnish Society of Soil Sciences, which became affiliated to the IUSS. The society was originally established in 1971 but it remained relatively inactive. Currently, there are around 200 members in the Finnish Society of Soil Sciences. The members of the executive board cover different fields of soil science from geology to microbiology. Mission statement of the society is to promote the soil sciences and their application in Finland, to act as a forum for creation of better links between soil scientists, interested end users and the public, and to promote distribution and appreciation of general and Finnish research findings in soil science. Every second year the society organizes a national two-day long conference. In 2017 the theme 'circular economy' collected all together 57 presentations. The members of the incoming student division carried responsibility in practical co-ordination committee, acting also as session chairs. In the intervening years the society organizes a weekend excursion to neighboring areas. Lately we have explored the use of biochar in landscaping of Stockholm.

  8. Safety-related incidents at the Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Lehtinen, P.

    1986-03-01

    This report contains detailed descriptions of operating incidents and other safety-related matters at the Finnish nuclear power plants regarded as significant by the regulatory authority, the Finnish Centre for Radiation and Nuclear Safety. In this connection, an account is given of the practical actions caused by the incidents, and their significance to reactor safety is evaluated. The main features of the incidents are also described in the general Quartely Reports, Operation of Finnish Nuclear Power Plants, which are supplemented by this report intended for experts. (author)

  9. Safety-related incidents at the Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Lehtinen, P.

    1985-01-01

    This report contains detailed descriptions of operating incidents and other safety-related matters at the Finnish nuclear power plants regarded as significant by the regulatory authority, the Finnish Centre for Radiation and Nuclear Safety. In this connection, an account is given of the practical actions caused by the incidents, and their significance to reactor safety is evaluated. The main features of the incidents are also described in the general Quartely Reports, Operation of Finnish Nuclear Power Plants, which are supplemented by this report intended for experts. (author)

  10. How Do Finnish Teacher Educators Implement Entrepreneurship Education?

    Science.gov (United States)

    Seikkula-Leino, Jaana; Satuvuori, Timo; Ruskovaara, Elena; Hannula, Heikki

    2015-01-01

    Purpose: The purpose of this paper is to ascertain how the people who train Finnish teachers implement entrepreneurship education in the guidance they provide. The authors show how learning through, for and about entrepreneurship manifests in the self-evaluations of Finnish teacher educators. Design/methodology/approach: Data were collected in…

  11. New Finnish radiation law

    International Nuclear Information System (INIS)

    Niittyla, A.

    1992-01-01

    The new Finnish Radiation Act will enter into force on 1.1.1992. The Act aims to protect man's health against the harmful effects of radiation. The Act applies to the utilization of ionising radiation and natural radiation as well as non-ionising radiation. It emphasises the fact that a licensed organization or entrepreneur carrying out a practice which causes radiation exposure is responsible for the safety of the activity. The organization or entrepreneur in question is also obliged to take care of radioactive waste. The provisions of the Radiation Act which apply to monitoring of worker exposure are also applied to the use of nuclear energy. Activities involving the use of radiation and the use of nuclear energy are regulated by one authority, the Finnish Centre for Radiation and Nuclear Safety. (author)

  12. Safety-related occurrences at the Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Reponen, H.; Viitasaari, O.

    1985-04-01

    This report contains detailed descriptions of operating incidents and other safety-related matters at the Finnish nuclear power plants regarded as significant by the regulatory authority, the Finnish Centre for Radiation and Nuclear Safety. In this connection, an account is given of the practical actions caused by the incidents, and their significance to reactor safety is evaluated. The main features of the incidents are also described in the general Quartely Report for this period, Operation of Finnish Nuclear Power Plants (STUK-B-YTO 7), which is supplemented by this report intended for experts. (author)

  13. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Reponen, H.; Viitasaari, O.

    1985-09-01

    These general reviews of the operation of the Finnish nuclear power plants concentrate on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as significant. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. The report also includes a summary of the radiation safety of the personnel and the environment and tabulated data on the production and capacity factors of the plants. (author)

  14. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    1988-04-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tubulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment

  15. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Lehtinen, P.

    1986-08-01

    These general reviews of the operation of the Finnish nuclear power plants concentrate on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. (author)

  16. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Reponen, H.; Viitasaari, O.; Lehtinen, P.

    1985-11-01

    These general reviews of the operation of the Finnish nuclear power plants concentrate on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as significant. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. The report also includes a summary of the radiation safety of the personnel and the environment and tabulated data on the production and load factors of the plants. (author)

  17. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Heimburger, H.

    1988-08-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment

  18. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Ottosson, C.

    1989-05-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment

  19. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Haenninen, R.; Koponen, H.; Nevander, O.; Paltemaa, R.; Poellaenen, I.; Rannila, P.; Valtonen, K.; Vilkamo, O.

    1988-02-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment

  20. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Haenninen, R.

    1988-09-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hzard to the personnel or the environment

  1. FIN-EPOS - Finnish national initiative of the European Plate Observing System: Bringing Finnish solid Earth infrastructures into EPOS

    Science.gov (United States)

    Vuorinen, Tommi; Korja, Annakaisa

    2017-04-01

    FIN-EPOS consortium is a joint community of Finnish national research institutes tasked with operating and maintaining solid-earth geophysical and geological observatories and laboratories in Finland. These national research infrastructures (NRIs) seek to join EPOS research infrastructure (EPOS RI) and further pursue Finland's participation as a founding member in EPOS ERIC (European Research Infrastructure Consortium). Current partners of FIN-EPOS are the University of Helsinki (UH), the University of and Oulu (UO), Finnish Geospatial Research Institute (FGI) of the National Land Survey (NLS), Finnish Meteorological Institute (FMI), Geological Survey of Finland (GTK), CSC - IT Center for Science and MIKES Metrology at VTT Technical Research Centre of Finland Ltd. The consortium is hosted by the Institute of Seismology, UH (ISUH). The primary purpose of the consortium is to act as a coordinating body between various NRIs and the EPOS RI. FIN-EPOS engages in planning and development of the national EPOS RI and will provide support in EPOS implementation phase (IP) for the partner NRIs. FIN-EPOS also promotes the awareness of EPOS in Finland and is open to new partner NRIs that would benefit from participating in EPOS. The consortium additionally seeks to advance solid Earth science education, technologies and innovations in Finland and is actively engaging in Nordic co-operation and collaboration of solid Earth RIs. The main short term objective of FIN-EPOS is to make Finnish geoscientific data provided by NRIs interoperable with the Thematic Core Services (TCS) in the EPOS IP. Consortium partners commit into applying and following metadata and data format standards provided by EPOS. FIN-EPOS will also provide a national Finnish language web portal where users are identified and their user rights for EPOS resources are defined.

  2. Safety-related occurrences at the Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Viitasaari, O.; Rantavaara, A.

    1984-03-01

    This report contains detailed descriptions of operating incidents and other safety-related matters at the Finnish nuclear power plants regarded as significant by the regulatory authority, the Finnish Centre for Radiation and Nuclear Safety. In this connection, an account is given of the practical actions caused by the incidents, and their significance to reactor safety is evaluated. The main features of the incidents are also described in the general Quartely Report for this period, Operation of Finnish Nuclear Power Plants (STL-B-RTO-83/7), which is supplemented by this report intended principally for experts. (author)

  3. Finnish and Swedish business cycles in a global context

    DEFF Research Database (Denmark)

    Bergman, Ulf Michael

    2008-01-01

    This paper evaluates the decisions made by the Finnish government to join EMU and the Swedish government not to join EMU in the early 1990s. Focusing on the characteristics of business cycles during the postwar period, we find that output fluctuations in Sweden and Finland are correlated to two...... measures of the international business cycle, a European and a non-European cycle. The Finnish cycle has become more synchronized to the European cycle but less synchronized to the non-EU cycle after 1999. For Sweden we find the opposite result. The decision by the Finnish government to join EMU...

  4. Visual impairment in Finnish Usher syndrome type III.

    NARCIS (Netherlands)

    Plantinga, R.F.; Pennings, R.J.E.; Huygen, P.L.M.; Sankila, E.M.; Tuppurainen, K.; Kleemola, L.; Cremers, C.W.R.J.; Deutman, A.F.

    2006-01-01

    PURPOSE: To evaluate visual impairment in Finnish Usher syndrome type 3 (USH3) and compare this with visual impairment in Usher syndrome types 1b (USH1b) and 2a (USH2a). METHODS: We carried out a retrospective study of 28 Finnish USH3 patients, 24 Dutch USH2a patients and 17 Dutch USH1b patients.

  5. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1990-03-01

    In the Quarterly Reports on the operation of the Finnish nuclear power plants such incidents and observations are described relating to nuclear and radiation safety which the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, considers safety-related. During the third quarter of 1989 the Finnish nuclear power plant units Loviisa 1 and 2 and TVO I and II were in commercial operation for most of the time. Nuclear electricity accounted for 39.0% of the total Finnish electricity production in this quarter. The load factor average of the nuclear power plant units was 78.9%. At Loviisa 1, two holes were found in the feedwater distributor of one steam generator. Corresponding wall thinning corrosion was also detected in the walls of two other distributors. The holes were found on the feedwater distributor upper surface in the joint of the secondary circuit feedwater pipe. One hole was about 20 mm x 50 mm in size and the other was a pit hole ca 5 mm in diameter. Metal power had entered the primary circuit at TVO I. This was observed during a post-scram plant start-up. Several control rod drive units had become jammed so tight that control rod withdrawal failed. Metal powder did not hamper reactor scram under the prevailing circumstances because the drive units are prone to jamming only after a control rod is almost fully inserted and because the forces which insert a control rod by various means (electrical, hydraulic) are 6-8 fold compared with the withdrawing force

  6. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Reponen, H.; Viitasaari, O.

    1985-01-01

    This general review of the operation of the Finnish nuclear power plants in the second quarter of the year 1984 concentrates on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as significant. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. The report also includes a summary of the radiation safety of the personnel and the environment and tabulated data on the production and availability of the plants. (author)

  7. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Reponen, H.; Viitasaari, O.

    1985-05-01

    This general review of the operation of the Finnish nuclear power plants in the third quarter of the year 1984 concentrates on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as significant. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. The report also includes a summary of the radiation safety of the personnel and the environment and tabulated data on the production and capacity factors of the plants. (author)

  8. The styles of the Finnish nuclear waste policy

    International Nuclear Information System (INIS)

    Kojo, Matti

    2010-09-01

    The Finnish government determined the aims and schedule for nuclear waste management in 1983. Nearly three decades later spent nuclear fuel (SNF) management is approaching the construction licensing phase of the repository, on schedule. The parliamentary decision on the final disposal of SNF was taken almost unanimously in 2001. The location of the SNF facility was chosen at the same time. The smoothness of this raises questions about the main factors behind the progress in Finland. The aim of the paper is to analyse the Finnish nuclear waste policy from the point of view of policy style. In the paper policy style is defined as 'the interaction between (a) the government's approach to problem-solving and (b) the relationship between government and the other actors in policy process'. According to this definition by Richardson, Gustafsson and Jordan, the focus of style is both on policymaking and on implementation. The policy style approach is used to identify the standard operating procedures of Finnish nuclear waste policy. The paper aims to contribute to the discussion on the formation of national nuclear waste policy and its institutions by analysing the Finnish case

  9. Genotyping and surveillance for scrapie in Finnish sheep

    Directory of Open Access Journals (Sweden)

    Hautaniemi Maria

    2012-07-01

    Full Text Available Abstract Background The progression of scrapie is known to be influenced by the amino acid polymorphisms of the host prion protein (PrP gene. There is no breeding programme for TSE resistance in sheep in Finland, but a scrapie control programme has been in place since 1995. In this study we have analysed PrP genotypes of total of 928 purebred and crossbred sheep together with the data of scrapie survey carried out in Finland during 2002–2008 in order to gain knowledge of the genotype distribution and scrapie prevalence in Finnish sheep. Results The ARQ/ARQ genotype was the most common genotype in all breeds studied. ARR allele frequency was less than 12% in purebred Finnish sheep and in most genotypes heterozygous for ARR, the second allele was ARQ. The VRQ allele was not detected in the Grey race sheep of Kainuu or in the Aland sheep, and it was present in less than 6% of the Finnish Landrace sheep. Leucine was the most prominent amino acid found in codon 141. In addition, one novel prion dimorphisms of Q220L was detected. During the scrapie survey of over 15 000 sheep in 2002–2008, no classical scrapie cases and only five atypical scrapie cases were detected. Conclusions The results indicate that the Finnish sheep populations have genetically little resistance to classical scrapie, but no classical scrapie was detected during an extensive survey in 2002–2008. However, five atypical scrapie cases emerged; thus, the disease is present in the Finnish sheep population at a low level.

  10. On the early history of the Finnish Meteorological Institute

    Science.gov (United States)

    Nevanlinna, H.

    2014-03-01

    This article is a review of the foundation (in 1838) and later developments of the Helsinki (Finland) magnetic and meteorological observatory, today the Finnish Meteorological Institute (FMI). The main focus of the study is in the early history of the FMI up to the beginning of the 20th century. The first director of the observatory was Physics Professor Johan Jakob Nervander (1805-1848). He was a famous person of the Finnish scientific, academic and cultural community in the early decades of the 19th century. Finland was an autonomously part of the Russian Empire from 1809 to 1917, but the observatory remained organizationally under the University of Helsinki, independent of Russian scientific institutions, and funded by the Finnish Government. Throughout the late-19th century the Meteorological Institute was responsible of nationwide meteorological, hydrological and marine observations and research. The observatory was transferred to the Finnish Society of Sciences and Letters under the name the Central Meteorological Institute in 1881. The focus of the work carried out in the Institute was changed gradually towards meteorology. Magnetic measurements were still continued but in a lower level of importance. The culmination of Finnish geophysical achievements in the 19th century was the participation to the International Polar Year programme in 1882-1883 by setting up a full-scale meteorological and magnetic observatory in Sodankylä, Lapland.

  11. Bibliography of Finnish forestry literature

    International Nuclear Information System (INIS)

    1996-01-01

    The bibliography consists primarily of material from Finnish publications. Although, relevant articles published outside Finland are also included in the bibliography. The references listed in the bibliography include articles on forestry sciences taken from 200 different Finnish journals as well as all the material in the journals published by the various departments of forestry of the University of Helsinki, the Society of Forestry in Finland and the Finnish Forest Research Institute. The bibliography is published four times per year, and is compiled annually in a single volume. The bibliography consists of about 2000 references per year. The material is categorized according to the FDC (Forest Decimal Classification, formerly Oxford Decimal Classification). The bibliography contains material of following subject categories: (0) Forests, forestry and the utilization of forest products (general). Dictionaries. Bibliographies. (1) Factors of the environment. Biology. (2) Silviculture. (3) Work science (Work studies). Harvesting of wood: Logging and transport. Forest engineering. (4) Forest injuries and protection. (5) Forest mensuration. Increment; development and structure of stands. Surveying and mapping. (6) Forest management. Business economics of forestry. Administration and organization of forest enterprises. (7) Marketing of forest products: Economics of forest transport and the wood industries. (8) forest products and their utilization. (9) Forests and forestry from the national point of view. Social economics of forestry. The bibliography includes author and subject indexes

  12. Bibliography of Finnish forestry literature

    International Nuclear Information System (INIS)

    1997-01-01

    The bibliography consists primarily of material from Finnish publications. Although, relevant articles published outside Finland are also included in the bibliography. The references listed in the bibliography include articles on forestry sciences taken from 200 different Finnish journals as well as all the material in the journals published by the various departments of forestry of the University of Helsinki, the Society of Forestry in Finland and the Finnish Forest Research Institute. The bibliography is published four times per year, and is compiled annually in a single volume. The bibliography consists of about 2000 references per year. The material is categorised according to the FDC (Forest Decimal Classification, formerly Oxford Decimal Classification). The bibliography contains material of following subject categories: (0) Forests, forestry and the utilisation of forest products (general). Dictionaries. Bibliographies. (1) Factors of the environment. Biology. (2) Silviculture. (3) Work science (Work studies). Harvesting of wood: Logging and transport. Forest engineering. (4) Forest injuries and protection. (5) Forest mensuration. Increment; development and structure of stands. Surveying and mapping. (6) Forest management. Business economics of forestry. Administration and organisation of forest enterprises. (7) Marketing of forest products: Economics of forest transport and the wood industries. (8) forest products and their utilisation. (9) Forests and forestry from the national point of view. Social economics of forestry. The bibliography includes author and subject indexes

  13. Finnish support programme to IAEA safeguards. Annual report 1994

    International Nuclear Information System (INIS)

    Tarvainen, M.

    1995-05-01

    Implementation of the Finnish Support Programme to IAEA Safeguards (FINSP) during the calender year in question is summarized. FINSP is carried out trough separate tasks concentrating on verification of nuclear material, training and expert services to the IAEA. In addition to the Finnish summary, the report includes detailed description of each task in English

  14. Literacy Development among Language Minority Background and Dyslexic Children in Finnish Orthography Context

    Science.gov (United States)

    Sikiö, Riitta; Siekkinen, Martti; Holopainen, Leena

    2016-01-01

    This study examines the development of reading and writing from first to second grade in transparent orthography (Finnish) among three groups: language minority children (n = 49), Finnish children at risk of reading difficulties (n = 347), and Finnish speaking children (n = 1747). Findings indicated that reading and writing skills in the language…

  15. Constructions of Bilingualism in Finnish Government Programmes and a Newspaper Discussion Site Debate

    Science.gov (United States)

    Pöyhönen, Sari; Saarinen, Taina

    2015-01-01

    The concept of bilingualism in Finnish political discourse is predominantly used in the meaning of official or state bilingualism, focusing on the two constitutionally defined "national languages;" that is, Finnish and Swedish. Legally, both Finnish and Swedish-speakers have a right for public services, such as schooling or health care,…

  16. Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred

    DEFF Research Database (Denmark)

    Jensen, Minna Grønning; Campos, Raul I.; Fagerberg, Christina

    2011-01-01

    The disease phenotype of transthyretin (TTR) is dramatically influenced by single point mutations in the TTR gene. Herein, we report on a novel mutation D99N (Asp99Asn) in TTR found in a Danish kindred. None of the family members carrying this mutation have so far shown any clinical signs...... of amyloidosis. One carrier found compound heterozygous for TTR D99N and L111M (Leu111Met) associated with cardiac amyloid is asymptomatic (42 years). Disease severity can often be linked to both the kinetics of fibril formation and the degree of destabilisation of the native state. In this study, we show...

  17. Structural Development of Finnish Universities: Achieving Competitiveness and Academic Excellence

    Science.gov (United States)

    Tirronen, Jarkko; Nokkala, Terhi

    2009-01-01

    This paper discusses strategic instruments that are used to enhance the competitiveness of Finnish universities in the context of globalisation, internationalisation and commercialisation of research and education. The Finnish higher education system is currently undergoing a major policy reform, which aims to enhance the competitiveness of…

  18. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Lehtinen, Pekka

    1987-05-01

    These general reviews of the operation of the Finnish nuclear power plants concentrate on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the perssonnel or the environment. For remedying certain defects found in the administrative procedures concerning plant operation and maintenance, the Loviisa power plant was shut down for several days

  19. Finnish market entry planning of franchising Kungfu catering

    OpenAIRE

    Liu, Yun

    2011-01-01

    The purpose of this thesis was to carry out a market entry planning by franchising Kungfu catering in Finland. Kungfu catering was a typical Chinese fast food restaurant, of which there was a gap in Finnish fast food market. McDonald’s and Hesburger were succesful examples of franchise business, experiences of those 2 restaurants were used for reference to create a suitable franchise strategy for Kungfu Finland. Finnish market entry planning of Kungfu Finland has been explained from several a...

  20. Towards automated processing of clinical Finnish: sublanguage analysis and a rule-based parser.

    Science.gov (United States)

    Laippala, Veronika; Ginter, Filip; Pyysalo, Sampo; Salakoski, Tapio

    2009-12-01

    In this paper, we present steps taken towards more efficient automated processing of clinical Finnish, focusing on daily nursing notes in a Finnish Intensive Care Unit (ICU). First, we analyze ICU Finnish as a sublanguage, identifying its specific features facilitating, for example, the development of a specialized syntactic analyser. The identified features include frequent omission of finite verbs, limitations in allowed syntactic structures, and domain-specific vocabulary. Second, we develop a formal grammar and a parser for ICU Finnish, thus providing better tools for the development of further applications in the clinical domain. The grammar is implemented in the LKB system in a typed feature structure formalism. The lexicon is automatically generated based on the output of the FinTWOL morphological analyzer adapted to the clinical domain. As an additional experiment, we study the effect of using Finnish constraint grammar to reduce the size of the lexicon. The parser construction thus makes efficient use of existing resources for Finnish. The grammar currently covers 76.6% of ICU Finnish sentences, producing highly accurate best-parse analyzes with F-score of 91.1%. We find that building a parser for the highly specialized domain sublanguage is not only feasible, but also surprisingly efficient, given an existing morphological analyzer with broad vocabulary coverage. The resulting parser enables a deeper analysis of the text than was previously possible.

  1. A cohort effect on serum testosterone levels in Finnish men

    DEFF Research Database (Denmark)

    Perheentupa, A; Mäkinen, J; Laatikainen, T

    2013-01-01

    To investigate whether a population-level decline in serum testosterone exists in Finnish men. In comparison with other European populations, Finnish men have compared well in the studies of reproductive health (i.e. semen quality, incidence of cryptorchidism and testicular cancer); thus, we...... expected no significant cohort-dependent decrease in serum testosterone....

  2. How Is Interreligious Sensitivity Related to Finnish Pupils' Religiousness Profiles?

    Science.gov (United States)

    Kuusisto, Elina; Kuusisto, Arniika; Kallioniemi, Arto

    2016-01-01

    This paper examines, through a non-probability sample of 451 Finnish lower secondary-school pupils belonging to the 15- to 16-year-old age group, how interreligious sensitivity is related to religiousness profiles of Finnish youth. The data were gathered in two geographical locations: Helsinki, Finland's capital, and a smaller municipality in the…

  3. Finnish Pupils' Views on the Place of Religion in School

    Science.gov (United States)

    Kuusisto, Arniika; Poulter, Saila; Kallioniemi, Arto

    2017-01-01

    This mixed method study examines Finnish pupils' (N = 825; age groups 12-13, 15-16) views on the place of religion in the public school. Religious landscape in Finnish society has changed significantly in recent years, as the "new" diversity (Vertovec 2015) has supplemented the "old" one. The role of institutionalized religion…

  4. HANSENULA WICKERHAMII SP. N., A NEW YEAST FROM FINNISH SOIL

    Science.gov (United States)

    Capriotti, Augusto

    1961-01-01

    Capriotti, Augusto (l'Università di Perugia, Perugia, Italy). Hansenula wickerhamii sp. n., a new yeast from Finnish soil. J. Bacteriol. 82:259–360. 1961.—Hansenula wickerhamii sp. n. is described; it was isolated from a Finnish soil, and is named in honor of Lynferd J. Wickerham. Images PMID:13690638

  5. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Lehtinen, Pekka

    1987-07-01

    These general reviews of the operation of the Finnish nuclear power plants concentrate on such events and discoveries related to reactor and radiation safety that the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. No event in the report period, or in the whole year of 1986, essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment. For remedying certain defects found in the adminstrative procedures concerning plant operation and maintenance, the Loviisa power plant was shut down for several days in September

  6. Outsourcing Equality: Migrant Care Worker Imaginary in Finnish Media

    Directory of Open Access Journals (Sweden)

    Camilla Nordberg

    2016-10-01

    Full Text Available Implications from the restructuring of Nordic eldercare include the incorporation of new categories of care workers and a redefinition of the terms of citizenship and participation in working life. Drawing on the idea that policy actors script care worker subjectivities, this article examines print media as a key arena where the cultural imaginary of care work is played out. The media has the potential to accommodate ideological complexity through the possible range of participatory actors. From the scripts promoted through the mediascape, we can learn about the positions understood as being (inappropriate for migrant care workers. This study draws on the analysis of news and feature stories from 2003 to 2013 in the largest Finnish daily, Helsingin Sanomat, and in the periodical Kuntalehti, published by the Finnish Association of Local and Regional Authorities. The article points to tensions in Finnish media discourse, identifying ambiguous occupational scripts for migrant care workers—rooted in neoliberal repertoires of self-sufficiency and normative individualism on the one hand and helplessness and naivety on the other hand. It draws attention to an unsettling construction whereby migrant care workers are excluded from a long-term contract with the Finnish care labor market, and where social equality is conditioned to global redistribution.

  7. Characteristics and international comparability of the Finnish matrix sentence test in cochlear implant recipients.

    Science.gov (United States)

    Dietz, Aarno; Buschermöhle, Michael; Sivonen, Ville; Willberg, Tytti; Aarnisalo, Antti A; Lenarz, Thomas; Kollmeier, Birger

    2015-01-01

    The first Finnish sentence-based speech test in noise--the Finnish matrix sentence test--was recently developed. The aim of this study was to determine the characteristics of the new test with respect to test-retest reliability, speech recognition curve, and international comparability in Finnish cochlear implant (CI) recipients. The speech reception thresholds (SRT) were measured by means of an adaptive test procedure and compared with the results of the traditional Finnish word test. Additional measurements for concurrent slope and SRT estimation were conducted to determine the speech recognition curve and to check the test-retest reliability. The measurements were performed on 78 Finnish CI recipients. In a subset of 25 patients, additional measurements for test-retest reliability and slope determination were performed. The mean SRT was -3.5 ± 1.7 dB SNR, with only a weak correlation with the Finnish word test. Test-retest reliability was within ± 1 dB and the mean slope of the speech recognition curve was 14.6 ± 3.6 %/dB. The rehabilitation results were similar to the results published for the German matrix test. The Finnish matrix test was found to be suitable and efficient in CI recipients with similar characteristics as the German matrix test.

  8. Spiritually Ours, Factually Yours: Karelia and Russia in Finnish Public Consciousness

    NARCIS (Netherlands)

    Laine, J.; Velde, B.M.R. van der

    2017-01-01

    Based on an analysis of the leading Finnish newspaper, Helsingin Sanomat, this paper explores Finnish attitudes towards and understandings of Russia. It pays special attention to the so-called Karelia Question and the way it has shaped public discussion in Finland. The article seeks to investigate

  9. Finnish energy technology programmes 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    The Finnish Technology Development Centre (Tekes) is responsible for the financing of research and development in the field of energy production technology. A considerable part of the financing goes to technology programmes. Each technology programme involves major Finnish institutions - companies, research institutes, universities and other relevant interests. Many of the energy technology programmes running in 1998 were launched collectively in 1993 and will be completed at the end of 1998. They are complemented by a number of other energy-related technology programmes, each with a timetable of its own. Because energy production technology is horizontal by nature, it is closely connected with research and development in other fields, too, and is an important aspect in several other Tekes technology programmes. For this reason this brochure also presents technology programmes where energy is only one of the aspects considered but which nevertheless contribute considerably to research and development in the energy production sector

  10. Source Taxation of Technological Services in Finnish Tax Treaties

    OpenAIRE

    Kiviranta, Tuomas

    2016-01-01

    In this study, I analyze the various means of source taxation of technological and other services permitted by Finnish double taxation conventions and the future of source taxation of technological and other services. I attempt to shed light on the various means of source taxation of technological services permitted by Finnish tax treaties and by tax treaties also more generally. I analyze 1) the taxation of technological services in the source country as the profits of a permanent establishm...

  11. Musical Sophistication and the Effect of Complexity on Auditory Discrimination in Finnish Speakers

    Science.gov (United States)

    Dawson, Caitlin; Aalto, Daniel; Šimko, Juraj; Vainio, Martti; Tervaniemi, Mari

    2017-01-01

    Musical experiences and native language are both known to affect auditory processing. The present work aims to disentangle the influences of native language phonology and musicality on behavioral and subcortical sound feature processing in a population of musically diverse Finnish speakers as well as to investigate the specificity of enhancement from musical training. Finnish speakers are highly sensitive to duration cues since in Finnish, vowel and consonant duration determine word meaning. Using a correlational approach with a set of behavioral sound feature discrimination tasks, brainstem recordings, and a musical sophistication questionnaire, we find no evidence for an association between musical sophistication and more precise duration processing in Finnish speakers either in the auditory brainstem response or in behavioral tasks, but they do show an enhanced pitch discrimination compared to Finnish speakers with less musical experience and show greater duration modulation in a complex task. These results are consistent with a ceiling effect set for certain sound features which corresponds to the phonology of the native language, leaving an opportunity for music experience-based enhancement of sound features not explicitly encoded in the language (such as pitch, which is not explicitly encoded in Finnish). Finally, the pattern of duration modulation in more musically sophisticated Finnish speakers suggests integrated feature processing for greater efficiency in a real world musical situation. These results have implications for research into the specificity of plasticity in the auditory system as well as to the effects of interaction of specific language features with musical experiences. PMID:28450829

  12. Musical Sophistication and the Effect of Complexity on Auditory Discrimination in Finnish Speakers.

    Science.gov (United States)

    Dawson, Caitlin; Aalto, Daniel; Šimko, Juraj; Vainio, Martti; Tervaniemi, Mari

    2017-01-01

    Musical experiences and native language are both known to affect auditory processing. The present work aims to disentangle the influences of native language phonology and musicality on behavioral and subcortical sound feature processing in a population of musically diverse Finnish speakers as well as to investigate the specificity of enhancement from musical training. Finnish speakers are highly sensitive to duration cues since in Finnish, vowel and consonant duration determine word meaning. Using a correlational approach with a set of behavioral sound feature discrimination tasks, brainstem recordings, and a musical sophistication questionnaire, we find no evidence for an association between musical sophistication and more precise duration processing in Finnish speakers either in the auditory brainstem response or in behavioral tasks, but they do show an enhanced pitch discrimination compared to Finnish speakers with less musical experience and show greater duration modulation in a complex task. These results are consistent with a ceiling effect set for certain sound features which corresponds to the phonology of the native language, leaving an opportunity for music experience-based enhancement of sound features not explicitly encoded in the language (such as pitch, which is not explicitly encoded in Finnish). Finally, the pattern of duration modulation in more musically sophisticated Finnish speakers suggests integrated feature processing for greater efficiency in a real world musical situation. These results have implications for research into the specificity of plasticity in the auditory system as well as to the effects of interaction of specific language features with musical experiences.

  13. The XXXV annual conference of the Finnish physical society. Proceedings

    International Nuclear Information System (INIS)

    Kolhinen, V.; Eskola, K.J.; Ruuskanen, V.; Tuominen, K.

    2001-01-01

    The 35th Physics Days of the Finnish Physical Society will have the traditional structure with plenary lectures, short contributions of young researchers, poster sessions, and social events. The number of members of the society has exceeded 1000 and nearly half of them, more than 400, are expected to participate the Physics Days. The Finnish physicists and the Society can be proud of keeping up this tradition. The annual meeting of the Finnish Physical Society will take place during the Physics Days. I wish all the members of the Finnish Physical Society to attend the meeting and continue the discussions more informally at the conference dinner following the annual meeting. The fifth Magnus Ehrnrooth Price for Physics will be given during the opening ceremony of the Physics Days. Also the winners of the SOLIS competition for high school students will be announced. Traditionally, the Days will end by giving prices for the best poster and the best talk. The 35th Physics Days are held in the new congress center Jyvaeskylae Paviljonki and arranged by the University of Jyvaeskylae. The proceedings includes all the abstracts of the presentations given during the 35th Physics Days

  14. Identification of a Novel Dentin Matrix Protein-1 (DMP-1) Mutation and Dental Anomalies in a Kindred with Autosomal Recessive Hypophosphatemia

    OpenAIRE

    Turan, Serap; Aydin, Cumhur; Bereket, Abdullah; Akcay, Teoman; Güran, Tülay; Yaralioglu, Betul Akmen; Bastepe, Murat; Jüppner, Harald

    2009-01-01

    An autosomal recessive form of hypophosphatemia (ARHP) was recently shown to be caused by homozygous mutations in DMP1, the gene encoding dentin matrix protein-1 (DMP-1), a non-collagenous bone matrix protein with an important role in the development and mineralization of bone and teeth. Here, we report a previously not reported consanguineous ARHP kindred in which the three affected individuals carry a novel homozygous DMP-1 mutation. The index case presented at the age of 3 years with bowin...

  15. Finnish and English Children's Color Use to Depict Affectively Characterized Figures

    Science.gov (United States)

    Burkitt, Esther; Tala, Katri; Low, Jason

    2007-01-01

    Recent research has shown that children use colors systematically in relation to how they feel about certain colors and the figures that they draw. This study explored cultural differences between Finnish and English children's use of color to represent figures with contrasting emotional characters. One hundred and eight children (54 Finnish, 54…

  16. Finnish Fusion Research Programme Yearbook 1993-1994

    International Nuclear Information System (INIS)

    Karttunen, S.; Paettikangas, T.

    1995-05-01

    Finnish Fusion Research Programme (FFUSION) is one of the national energy research programmes funded by the Ministry of Trade and Industry and from 1995 by TEKES. National organization for fusion research is necessary for efficient and successful participation in international fusion programmes. FFUSION programme serves well for this purpose and it made possible to establish relations and the dialogue with the European Fusion Programme. The process led to the Finnish Association Euratom-TEKES in early 1995. The first period of the FFUSION programme (1993-1994) was preparation for the association to the Community Programme. The strategy was to emphasize fusion technology parallel with the basic fusion and plasma physics and to activate the related Finnish industry to collaborate and participate in the FFUSION programme and later in the European Fusion Programme. The key element in the strategy is the focusing our fairly small R and D effort to a few topics, which increases possibilities to be competitive in Europe. The physics programme in FFUSION deals mainly with theoretical and computational studies of radio-frequency heating in tokamak plasmas. Technology programme started with prestudies in 1993 and it concentrates into two areas: fusion reactor materials and remote handling systems. (8 figs., 3 tabs.)

  17. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1991-08-01

    In the Quarterly Reports on the operation of the Finnish nuclear power plants such events and observations are described relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety considers safety significant. Also other events of general interest are reported. The report also includes a summary of the radiation safety of the plants' workers and the environment, as well as tabulated data on the production and load factors of the plants. The Finnish nuclear power plant units Loviisa 1 and 2 as well as TVO I and II were in commercial operation during the whole first quarter of 1991. The load factor average was 99.1 %. Failures have been detected in the uppermost spacing lattices of nuclear fuel bundles removed from the Loviisa nuclear reactors. Further investigations into the significance of the failures have been initiated. In this quarter, renewed cooling systems for the instrumentation area were introduced at Loviisa 1. The modifications made in the systems serve to ensure reliable cooling of the area even during the hottest summer months when the possibility exists that the temperature of the automation equipment could rise too high causing malfunctions which could endanger plant safety. Occupational radiation doses and external releases of radioactivity were below prescribed limits in this quarter. Only small amounts of radioactive substances originating in nuclear power plants were detected in samples taken in the vicinity of nuclear power plants

  18. Awareness of child sex tourism among young Finnish travellers

    OpenAIRE

    Calderon Nurmi, Sara Liliana

    2014-01-01

    This bachelor’s thesis is written about one of the dark sides of tourism: child sex tourism. It is commisioned by a Finnish NGO, Reilun Matkailun Yhdistys and the aim was to conduct a research in order to find out about the awareness and attitudes of young Finnish travelers about child sex tourism. The theoretical framework consists of theory about child sex tourism and abot the much wider problem from which child sex tourism is origined: commercial sexual exploitation of children. Furth...

  19. East and West on the Finnish Screen. Early Transnational Television in Finland

    NARCIS (Netherlands)

    Pajala, Mari

    2014-01-01

    abstractResearch on Finnish television history has so far emphasized Western influences. However, the Finnish television environment was also in many ways shaped by contacts with socialist television cultures. This article analyses the first volume (1960) of the television magazine Katso to trace

  20. Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease.

    Science.gov (United States)

    Unal Gulsuner, Hilal; Gulsuner, Suleyman; Mercan, Fatma Nazli; Onat, Onur Emre; Walsh, Tom; Shahin, Hashem; Lee, Ming K; Dogu, Okan; Kansu, Tulay; Topaloglu, Haluk; Elibol, Bulent; Akbostanci, Cenk; King, Mary-Claire; Ozcelik, Tayfun; Tekinay, Ayse B

    2014-12-23

    Essential tremor is one of the most frequent movement disorders of humans and can be associated with substantial disability. Some but not all persons with essential tremor develop signs of Parkinson disease, and the relationship between the conditions has not been clear. In a six-generation consanguineous Turkish kindred with both essential tremor and Parkinson disease, we carried out whole exome sequencing and pedigree analysis, identifying HTRA2 p.G399S as the allele likely responsible for both conditions. Essential tremor was present in persons either heterozygous or homozygous for this allele. Homozygosity was associated with earlier age at onset of tremor (P relationship to Parkinson disease.

  1. Brief Report: Syndromes in Autistic Children in a Finnish Birth Cohort

    Science.gov (United States)

    Timonen-Soivio, Laura; Vanhala, Raija; Malm, Heli; Hinkka-Yli-Salomäki, Susanna; Gissler, Mika; Brown, Alan; Sourander, Andre

    2016-01-01

    We studied the association between specific congenital syndromes and autism spectrum disorders (ASD) in the large Finnish Register material. Our data include all children diagnosed with ASD (n = 4441) according to Finnish Hospital Discharge Register in 1987-2000. Four controls per each case were matched to sex, birthplace, date of birth (±30 days)…

  2. Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene.

    OpenAIRE

    Jennings, J. E.; Georgitsi, M.; Holdaway, I.; Daly, Adrian; Tichomirowa, M.; Beckers, Albert; Aaltonen, Lauri A; Karhu, A.; Cameron, F. J.

    2009-01-01

    OBJECTIVE: Mutations in the aryl hydrocarbon receptor-interacting protein (AIP) were recently shown to confer a pituitary adenoma predisposition in patients with familial isolated pituitary adenomas (FIPA). We report a large Samoan FIPA kindred from Australia/New Zealand with an R271W mutation that was associated with aggressive pituitary tumors. DESIGN AND METHODS: Case series with germline screening of AIP and haplotype analyses among R271W families. RESULTS: This previously unreported kind...

  3. Energy potential of Finnish peatlands

    Energy Technology Data Exchange (ETDEWEB)

    Virtanen, K. (Geological Survey of Finland, Kuopio (Finland)); Valpola, S. (Geological Survey of Finland, Kokkola (Finland)), e-mail: kimmo.virtanen@gtk.fi, e-mail: samu.valpola@gtk.fi

    2011-07-01

    One-third of the Finnish land area is covered by mires and peat. GTK has investigated 2.0 million ha of the 9.3 million ha area covered by mires in Finland. According to the EU Commission, the broadly-based Finnish energy economy, with various energy sources, is the best in the EU. As a fuel, peat fulfils the goals of the EU energy policy in Finland well: it is local, its availability is good and the price is stable. The use of peat also enhances national security. At present, peat is used in around one hundred larger applications that co-generate electricity and heat. In Finland, the development of mires has led to several mire complex types and three main types: raised bogs in Southern Finland, aapa mires in Ostrobothnia and Lapland, and palsa mires in Northern Lapland. Peat layers are deepest in southern Finland and partly in the southern Finnish Lake area, the Region of North Karelia and in the area of central Lapland. The mean depth of geological mires is 1.41 m and the thickest drilled peat is 12.3 m. According to peat investigations, the national peat reserve totals 69.3 billion m3 in situ (peatlands larger than 20 hectares). The dry solids of peat are estimated at 6.3 billion tones. Sphagnum peat accounts for 54% and Carex peat for 45% of feasible peat reserves. Peatlands that are technically suitable for the peat industry cover a total area of 1.2 million ha and contain 29.6 billion m3 of peat in situ. Slightly humified peat suitable for horticultural and environmental use totals 5.9 billion m3 in situ. The energy peat reserve is 23.7 billion m3 in situ and its energy content is 12 800 TWh. (orig.)

  4. International outreach for promoting open geoscience content in Finnish university libraries - libraries as the advocates of citizen science awareness on emerging open geospatial data repositories in Finnish society

    Science.gov (United States)

    Rousi, A. M.; Branch, B. D.; Kong, N.; Fosmire, M.

    2013-12-01

    In their Finnish National Spatial Strategy 2010-2015 the Finland's Ministry of Agriculture and Forestry delineated e.g. that spatial data skills should support citizens everyday activities and facilitate decision-making and participation of citizens. Studies also predict that open data, particularly open spatial data, would create, when fully realizing their potential, a 15% increase into the turnovers of Finnish private sector companies. Finnish libraries have a long tradition of serving at the heart of Finnish information society. However, with the emerging possibilities of educating their users on open spatial data a very few initiatives have been made. The National Survey of Finland opened its data in 2012. Finnish technology university libraries, such as Aalto University Library, are open environments for all citizens, and seem suitable of being the first thriving entities in educating citizens on open geospatial data. There are however many obstacles to overcome, such as lack of knowledge about policies, lack of understanding of geospatial data services and insufficient know-how of GIS software among the personnel. This framework examines the benefits derived from an international collaboration between Purdue University Libraries and Aalto University Library to create local strategies in implementing open spatial data education initiatives in Aalto University Library's context. The results of this international collaboration are explicated for the benefit of the field as a whole.

  5. Guidelines for Finnish start-ups on how to utilize crowdfunding

    OpenAIRE

    Rouhiainen, Anneli

    2016-01-01

    This thesis aims to show how a Finnish start-up could benefit from crowdfunding.Other funding methods are explained shortly in the beginning and the rest of the thesis focusing on crowdfunding. The current Finnish legislation does not yet include anything aimed directly at crowdfunding, but a proposal is to be presented in spring 2016 to the ministry of Finance. There are some crowdfunding websites operating in Finland, including Mesenaatti.me and Invesdor.com. Other more popular we...

  6. Construct validity and reliability of the Finnish version of the Knee Injury and Osteoarthritis Outcome Score.

    Science.gov (United States)

    Multanen, Juhani; Honkanen, Mikko; Häkkinen, Arja; Kiviranta, Ilkka

    2018-05-22

    The Knee Injury and Osteoarthritis Outcome Score (KOOS) is a commonly used knee assessment and outcome tool in both clinical work and research. However, it has not been formally translated and validated in Finnish. The purpose of this study was to translate and culturally adapt the KOOS questionnaire into Finnish and to determine its validity and reliability among Finnish middle-aged patients with knee injuries. KOOS was translated and culturally adapted from English into Finnish. Subsequently, 59 patients with knee injuries completed the Finnish version of KOOS, Western Ontario and McMaster Osteoarthritis Index (WOMAC), Short-Form 36 Health Survey (SF-36) and Numeric Pain Rating Scale (Pain-NRS). The same KOOS questionnaire was re-administered 2 weeks later. Psychometric assessment of the Finnish KOOS was performed by testing its construct validity and reliability by using internal consistency, test-retest reliability and measurement error. The floor and ceiling effects were also examined. The cross-cultural adaptation revealed only minor cultural differences and was well received by the patients. For construct validity, high to moderate Spearman's Correlation Coefficients were found between the KOOS subscales and the WOMAC, SF-36, and Pain-NRS subscales. The Cronbach's alpha was from 0.79 to 0.96 for all subscales indicating acceptable internal consistency. The test-retest reliability was good to excellent, with Intraclass Correlation Coefficients ranging from 0.73 to 0.86 for all KOOS subscales. The minimal detectable change ranged from 17 to 34 on an individual level and from 2 to 4 on a group level. No floor or ceiling effects were observed. This study yielded an appropriately translated and culturally adapted Finnish version of KOOS which demonstrated good validity and reliability. Our data indicate that the Finnish version of KOOS is suitable for assessment of the knee status of Finnish patients with different knee complaints. Further studies are needed to

  7. Ensuring the operational safety of finnish nuclear power plants

    International Nuclear Information System (INIS)

    Vuorinen, A.

    1991-01-01

    The Finnish nuclear energy programme has been successful both from the safety and economical point of view. These achievements are based on different factors which are discussed in the paper. Finnish Centre for Radiation and Nuclear Safety (STUK) has specified the technical requirements and procedures to be followed in the design, construction, commissioning and operation of NPPs in a series of guides. The guides are quite demanding and latest results of safety research and technical development are taken into account. Regulatory supervision of Finnish NPPs is comprehensive. As an example of this the regulatory inspection program for operational phase is presented. An important way to ensure operational safety of a NPP is to define a set of limits and conditions to identify limiting safety envelope for plant operation. Practices in Finland are reviewed in the paper. The strategy of Defence in Depth is amongst the fundamental principles of nuclear safety. Two corollary principles of defence of depth are accident prevention and accident mitigation. Means used in following these principles are discussed. (author)

  8. Cross-cultural differences of self-reported oral health behaviour in Japanese and Finnish dental students.

    Science.gov (United States)

    Kawamura, M; Honkala, E; Widström, E; Komabayashi, T

    2000-02-01

    To determine whether any differences existed in dental health behaviour between Japanese and Finnish dental students. Hiroshima University School of Dentistry and the University of Helsinki. Comparison of cross-cultural differences of self-reported oral health behaviour. Dental students, 337 in Japan and 113 in Finland. Subjects were surveyed using the Japanese and Finnish versions of a 20-item questionnaire entitled Hiroshima University--Dental Behavioural Inventory (HU-DBI). Only 2 per cent of Finnish students reported that they put off going to the dentist until they had toothache, compared to 56 per cent of Japanese students. Similarly, significantly more Japanese students thought that their teeth were getting worse despite their daily brushing, compared to their Finnish peers. The mean HU-DBI score of Year 1 Finnish students was higher than that of their Japanese peers, which suggested a higher level of dental health awareness in Finnish students upon entry into dental school. The mean scores of the Japanese students were lower than those of their Finnish peers until Year 3. The mean scores of Year 5 and Year 6 Japanese students were higher than that of Year 1 students, indicating raised self-care levels influenced by the course in preventive dentistry. The gender difference of the HU-DBI score was not a major feature in either country. Self-reported oral health behaviours seemed to be very different between the two countries, which reflected different culture and/or health education systems of the students.

  9. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1993-09-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations, relating to nuclear safety and radiation protection which the Finnish Centre for Radiation and Nuclear Safety considers safety significant. Safety-enhancing modifications at the nuclear power plants and issues relating to the use of nuclear energy which are of general interest are also reported. The reports include a summary of the radiation safety of plant personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the first quarter of 1993, a primary feedwater system pipe break occurred at Loviisa 2, in a section of piping after a feedwater pump. The break was erosion-corrosion induced. Repairs and inspections interrupted power generation for seven days. On the International Nuclear Event Scale the event is classified as a level 2 incident. Other events in the first quarter of 1993 had no bearing on nuclear safety and radiation protection

  10. Entrepreneurship in a Finnish public institution

    Directory of Open Access Journals (Sweden)

    Marin Burcea

    2012-12-01

    Full Text Available During the last decades the idea of entrepreneurship in public institutions has been the subject of intense debates, activities and academic research. The scopes of our article are to briefly underline the importance of developing an entrepreneurial spirit by presenting a case study from a Finnish local public administration and making aware the proactive aspect in the process of managing public institutions in Romania. Our hypotheses have been mainly of an interrogative nature. Hypothesis testing was achieved through the analysis of statistical data and conducting a set of sociological interviews with key people from Finnish institutions which were used in the survey. The results of the research emphasize that where there is an entrepreneurial behaviour with the local administration management, the community undergoes a process of conservation and development. The way in which they relate to community partners (such as entrepreneurs, non-profit organizations, citizens is essential to the entrepreneurial spirit within the local public institution.

  11. Finnish industry's energy requirement

    International Nuclear Information System (INIS)

    Punnonen, J.

    2000-01-01

    Industry uses around half of the electricity consumed in Finland. In 1999, this amounted to 42.3 TWh and 420 PJ of fuel. Despite the continual improvements that have been made in energy efficiency, energy needs look set to continue growing at nearly 2% a year. Finnish industrial output rose by some 5.5% in 1999. In energy-intensive sectors such as pulp and paper, output rose by 3.4%, in the metal industry by 4%, and in the chemical industry by 3.1%. Growth across Finnish industry is largely focused on the electrical and electronics industries, however, where growth last year was 24.3% The Finnish forest products industry used a total of 26.1 TWh of electricity last year, up 1% on 1998. This small increase was the result of the industry's lower-than-average operating rate in the early part of the year The metal industry used 7.2 TWh of electricity, an increase of 5.8% on 1998. Usage in the chemical industry rose by 2% to 5.2 TWh. Usage by the rest of industry totalled 3.8 TWh, up 2.3% on 1998. All in all, industry's use of electricity rose by 2% in 1999 to 42,3 TWh. Increased demand on industry's main markets in Europe will serve to boost industrial output and export growth this year. This increased demand will be particularly felt in energy-intensive industries in the shape of an increased demand for electricity. Overall, electricity demand is expected to grow by 3% this year, 1% more than industry's longterm projected electricity usage growth figure of 2%. The structure of industry's fuel use in Finland has changed significantly over the last 25 years. Oil, for example, now accounts for only some 10% of fuel use compared to the 40% typical around the time of the first oil crisis. Oil has been replaced by biofuels, peat, and natural gas. The pulp and paper industry is the largest industrial user of renewable energy sources in Finland, and uses wood-related fuels to cover nearly 70% of its fuel needs

  12. Engines without Fuel?--Empirical Findings on Finnish Higher Education Institutions as Education Exporters

    Science.gov (United States)

    Schatz, Monika

    2016-01-01

    In 2010, the Finnish Ministry of Education and Culture formulated Finland's first education export strategy. This policy document attributed Finnish Higher Education Institutions (HEIs) a significant role in the emerging sector by declaring them as "engines" of education export. Situated in a phenomenological approach towards…

  13. Finnish High Tech in China - A Study of Business Culture

    OpenAIRE

    Suhonen, Petri

    2013-01-01

    The objective of this thesis was to study the challenges caused by differences in Finnish and Chinese business cultures in the high technology industry. The study explains the main characteristics of the Chinese national and business cultures which every company operating in China will be dealing with, and offers examples of how these affect a high tech company. The study was conducted as a case study of a Finnish high technology company running a project in China. The company encountere...

  14. Management by Results at Finnish Universities

    Science.gov (United States)

    Kuoppala, Kari

    2005-01-01

    The funding of Finnish Universities has been based on a "management by results" strategy since 1991. This paper analyses the effects of this strategy on university management and administration. Empirically the study is based on material collected from four multidisciplinary universities. Theoretically it is based on organization theory…

  15. Cross-language similarity and difference in quantity categorization of Finnish and Japanese

    DEFF Research Database (Denmark)

    Yoshida, Kenji; J de Jong, Kenneth; Kruschke, John K

    2015-01-01

    quantity categorization was conducted with 22 Finnish and 20 Japanese listeners, using natural speech stimuli with systematically manipulated closure durations. Stimuli were created from Finnish and Japanese productions of both long and short plosives. In the naturally produced stimuli, the duration...... to be language specific, and such durational differences may interfere with categorization in an unfamiliar language....

  16. Internationalizing Services : Market research on exporting Finnish educational solutions to Nigeria

    OpenAIRE

    Asemokha, Agnes

    2012-01-01

    This thesis is aimed to bring clarity to the concept of internationalization and service (education) exports as an International Business tool. The study is commissioned by Finpros’ (The Finnish export organization) Future Learning Finland project an umbrella programme whose objective is internationalizing and exporting Finnish educational solutions to other countries. The commissioning party aims to use the study in its marketing activities. Therefore, this paper is built based on a hypothet...

  17. Finnish Kalevala and Estonian Kalevipoeg / Jaan Puhvel

    Index Scriptorium Estoniae

    Puhvel, Jaan, 1932-

    2003-01-01

    Tõlgitud kogumikust: The world of the Kalevala : essays in celebration of the 150 year jubilee of the publication of the Finnish national epic / ed. Kai Laitinen. Los Angeles : UCLA Centre for the Study of Folklore & Mythology, 1987

  18. Finnish vocational education and training in comparison: Strengths and weaknesses

    Directory of Open Access Journals (Sweden)

    Maarit Virolainen

    2014-12-01

    Full Text Available The study investigates how the Finnish model of providing initial vocational education and training (IVET has succeeded in terms of enhancing educational progress and employability. A relatively high level of participation in IVET makes the Finnish model distinctive from those of three other Nordic countries: Denmark, Norway and Sweden. All four Nordic countries have wellorganised labour markets and universal types of welfare states. Priority is given to goals related to equal opportunities and social inclusion. At the same time, these countries have different models of IVET. While the study compares the Finnish model of organising IVET to those of other Nordic countries, it also examines the German and UK models, which represent differing societal approaches to IVET. The differences in the outcomes of the IVET systems are described and analysed through reviewing secondary data provided by Eurydice and Eurostat, along with country reports produced in a Nordic comparative project, Nord-VET.

  19. 'From Start to Finnish': Handbook For Exporting A Theatre Play

    OpenAIRE

    Tanskanen, Milka; Mäkinen, Annemari

    2014-01-01

    Exporting Finnish culture is one of the themes the Finnish Ministry of Education and Culture has carried out over the last few years. ‘From Start to Finnish’ project was a mission to strenghten the state of theatre export in Finland. In the project, government subsidised theatres in Finland export their plays to the Edinburgh Festival Fringe, the largest arts festival in the world. The thesis is product-based as the authors created a handbook to combine all the steps to be taken when expo...

  20. BRCA2 Mutations in 154 Finnish Male Breast Cancer Patients

    Directory of Open Access Journals (Sweden)

    Kirsi Syrjäkoski

    2004-09-01

    Full Text Available The etiology and pathogenesis of male breast cancer (MBC are poorly known. This is due to the fact that the disease is rare, and large-scale genetic epidemiologic studies have been difficult to carry out. Here, we studied the frequency of eight recurrent Finnish BRCA2 founder mutations in a large cohort of 154 MBC patients (65% diagnosed in Finland from 1967 to 1996. Founder mutations were detected in 10 patients (6.5%, eight of whom carried the 9346(-2 A>G mutation. Two novel mutations (4075 delGT and 5808 del5 were discovered in a screening of the entire BRCA2 coding region in 34 samples. However, these mutations were not found in the rest of the 120 patients studied. Patients with positive family history of breast and/or ovarian cancer were often BRCA2 mutation carriers (44%, whereas those with no family history showed a low frequency of involvement (3.6%; P < .0001. Finally, we found only one Finnish MBC patient with 999 dell, the most common founder mutation in Finnish female breast cancer (FBC patients, and one that explains most of the hereditary FBC and MBC cases in Iceland. The variation in BRCA2 mutation spectrum between Finnish MBC patients and FBC patients in Finland and breast cancer patients in Iceland suggests that modifying genetic and environmental factors may significantly influence the penetrance of MBC and FBC in individuals carrying germline BRCA2 mutations in some populations.

  1. Finnish Secondary School Students' Interreligious Sensitivity

    Science.gov (United States)

    Holm, Kristiina; Nokelainen, Petri; Tirri, Kirsi

    2014-01-01

    The aim of this study was to assess the self-evaluations of Finnish secondary school students' (N?=?549) interreligious sensitivity. The data were collected from 12-16-year-old young people with a 15-item Interreligious Sensitivity Scale Questionnaire (IRRSSQ). The IRRSSQ is based on Abu-Nimer's Developmental Model of Interreligious Sensitivity,…

  2. Viral haemorrhagic septicaemia (VHS) outbreaks in Finnish-rainbow trout farms

    DEFF Research Database (Denmark)

    Raja-Halli, M.; Vehmas, T.K.; Rimaila-Parnanen, E.

    2006-01-01

    and NV gene regions of Finnish VHSV isolates collected between 2000 and 2004 revealed that all isolates were closely related, with 99.3 to 100% nucleotide identity, which suggests the same origin of infection. Phylogenetic analysis revealed that they were closely related to the old freshwater isolates...... from rainbow trout in Denmark and to one old marine isolate from cod in the Baltic Sea, and that they were located close to the presumed ancestral source. As the Finnish isolates induce lower mortality than freshwater VHSV isolates in infection experiments, they could represent an intermediate stage...

  3. Efficacy of the pentavalent rotavirus vaccine, RotaTeq®, in Finnish infants up to 3 years of age: the Finnish Extension Study.

    Science.gov (United States)

    Vesikari, Timo; Karvonen, Aino; Ferrante, Shannon Allen; Ciarlet, Max

    2010-11-01

    Rotavirus Efficacy and Safety Trial (REST) enrolled nearly 70,000 infants, of whom more than 23,000 were from Finland. REST determined the efficacy of the pentavalent rotavirus vaccine (RV5) against rotavirus-related hospitalisations and emergency department (ED) visits in the first year after vaccination. Finnish infants initially in REST transitioned into the Finnish Extension Study (FES), where they were followed for rotavirus-related hospitalisations and ED visits through their second year of life and beyond. FES identified 150 (31%) additional rotavirus gastroenteritis (RVGE) cases beyond those identified in REST in the Finnish participants. Overall, RV5 reduced RVGE hospitalisations and ED visits, regardless of the rotavirus serotype, by 93.8% (95% confidence interval [CI]: 90.8-95.9%) for up to 3.1 years following the last vaccine dose. Vaccine efficacy against combined hospitalisations and ED visits between ages 4 months to 11 months, 12 months to 23 months, and 24 months to 35 months was 93.9% (95% CI: 89.1-96.9%), 94.4% (95% CI: 90.2-97.0%), and 85.9% (95% CI: 51.6-97.2%), respectively. The reduction of hospitalisations and ED visits due to any acute gastroenteritis, rotavirus or not, was 62.4% (95% CI: 57.6-66.6%) over the entire follow-up period. The results from FES confirm that RV5 induces high and sustained protection against rotavirus-related hospitalisations and ED visits, and has a very substantial impact on all gastroenteritis-related hospitalisations and ED visits into the third year of life in Finnish children.

  4. Dematerialization in Finnish energy use, 1972-1996

    Energy Technology Data Exchange (ETDEWEB)

    Sun, J.W. [Turku School of Economics, P.O. Box 110, FIN-20521, Turku (Finland)

    2003-01-01

    This paper analyzes dematerialization, particularity decarbonization and energy saving with regard to Finnish energy use. The results show that Finland has achieved good results in decarbonization and energy saving. However, the results are not as impressive when compared to other developed countries.

  5. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1990-08-01

    During the first quarter of 1990 the Finnish nuclear power plant units Loviisa 1 and 2 and TVO I and II were in commercial operation for most of the time. Nuclear electricity accounted for 32.5% of the total Finnish electricity production during this quarter. The load factor average of the nuclear power plant units was 99.0%. An international nuclear event scale has been introduced for the classification of nuclear power plant events according to their nuclear and radiation safety significance. The scale first undergoes about a year long trial period in several countries. on the scale, events are divided into levels from 1 to 7 of which events at Level 7 are the most serious. Furthermore, Level 0 (Below Scale) is used for events with no safety significance. All events which occurred at the Finnish nuclear power plants this quarter are classified as Level 0. Occupational radiation doses and external releases of radioactivity were considerably below authorised limits. At the Loviisa plant, a back-up emergency feedwater system independent of the plant's other systems has been introduced which offers a new, alternative means of removing residual heat from the reactor. Owing to this system, the risk of a severe accident has been further reduced. At the TVO plants, systems have been introduced by which accident sequences which lead to containment failure could be eliminated and the consequences of a potential severe accident could be mitigated. In this report, also the release of short-lived radioactive materials along the transfer route of an irradiated sample is described which occured at the FiR 1 research reactor. The amounts of radioactive materials individuals received in their bodies in connection with this event were very low

  6. Foreign-language teaching and studying in Chilean and Finnish classrooms as seen by teachers

    Directory of Open Access Journals (Sweden)

    Harjanne Pirjo

    2017-09-01

    Full Text Available This article reports Chilean and Finnish foreign-language (FL teachers’ perceptions of teaching and study realities in their own FL classrooms. Communicative language teaching (CLT is used as the teaching–studying–learning methodological framework of an international KIELO project (= the acronym for Finnish “kieltenopetus” meaning “language teaching”, whose online survey was used to collect data for this article. We aim at answering the following research question: What are the FL teachers’ main approaches to teaching and studying in Chilean and Finnish FL classrooms and what is the FL classroom teaching and study reality like in these two countries? The data were collected from 83 Chilean and 147 Finnish FL teachers through an online survey covering 15 key themes of CLT and including 115 Likert-scale statements and 8 open-ended questions. In the descriptive data analysis, both Chilean and Finnish FL teachers claim that they encourage their students to use the target language considerably and that they use communicative oral tasks. For both groups of participants, however, teacher-centeredness and use of textbook score relatively high. The two-cluster analysis revealed a context-dependent cluster and a context-independent cluster. Context-dependent teachers tended to favor communicative oral tasks, real-life tasks and their own language tasks, whereas context-independent teachers favored more non-communicative tasks. Context-dependent teachers proved more student-centered than context-independent teachers. For Chilean and Finnish research participants, the use of mother tongue in foreign language classrooms appears to be an issue despite the growing need of foreign language communication.

  7. Reform, change, and continuity in Finnish health care.

    Science.gov (United States)

    Häkkinen, Unto; Lehto, Juhani

    2005-01-01

    This article describes some essential aspects of the Finnish political and governmental system and the evolution of the basic institutional elements of the health care system. We examine the developments that gave rise to a series of health care reforms and reform proposals in the late 1980s and early 1990s and relate them to changes in health care expenditure, structure, and performance. Finally, we discuss the relationship between policy changes, reforms, and health system changes and the strength of neo-institutional theory in explaining both continuity and change. Much of the change in Finnish health care can be explained by institutional path dependency. The tradition of strong but small local authorities and the lack of legitimate democratic regional authorities as well as the coexistence of a dominant Beveridge-style health system with a marginal Bismarckian element explain the specific path of Finnish health care reform. Public responsibility for health care has been decentralized to smaller local authorities (known as municipalities) more than in any other country. Even an exceptionally deep economic recession in the early 1990s did not lead to systems change; rather, the economic imperative was met by the traditional centralized policy pattern. Some of the developments of the 1990s are, however, difficult to explain by institutional theory. Thus, there is a need for testing alternative theories as well.

  8. Occlusion in the primary and early mixed dentitions in a group of Tanzanian and Finnish children.

    Science.gov (United States)

    Kerosuo, H

    1990-01-01

    Two high and two low socioeconomic areas were selected for the Tanzanian portion of this study, with all nursery schools located in those areas included, for a subtotal of 580 children. The Finnish group was comprised of a total of 575 Caucasian children examined. The Tanzanian children (83 percent Black African, 10 percent Asian, 7 percent Arab) had fewer occlusal anomalies than the Finnish children did. Finnish children had a 13-percent incidence rate of lateral cross-bite; among African children, 8 percent showed anterior crossbite; and among the combined Asian/Arab group of children, 10 percent had an anterior open bite. African children had significantly fewer prevalences of distal bite, lateral crossbite and crowding than Finnish children did.

  9. Occupational injuries in the Finnish furniture industry.

    Science.gov (United States)

    Aaltonen, M V

    1996-06-01

    The purpose of the study was to determine the types of occupational injuries that occur in the Finnish furniture industry and to see whether they differ as regards production type and company size. During a one-year registration period accident events, the actual and potential severity of the injuries, the causes of the accidents, and the measures needed to prevent such accidents were examined in 18 Finnish furniture factories of different types. An analysis of covariance determined the variables affecting the actual and potential severity of the injuries. The 214 accidents registered were lost-time injuries; two of them resulted in slight partial loss of fingertips. The disabling injury rate was 14.4 per 100 workers per year. Wooden furniture production and kitchen cupboard production in large companies had the highest rate. Accidents involving machines comprised half of the material. Saws were the most common machine type. Forty-two percent of the injuries could have been more severe; one injury could have been fatal. The injured persons and their foremen identified the causal factors of the accidents and the needed safety countermeasures well. Sixty-six percent of the causes and 65% of the safety countermeasures were associated with the actions of the workers and the workplace procedures. Nevertheless, only 6% of the identified safety countermeasures were put into force. It was estimated that, in 1987, 2000 on-site accidents leading to at least first-aid at some health care center occurred in the Finnish furniture industry. Special efforts should be taken to improve safety in furniture production in Finland.

  10. Finnish Archaeologists’ Contacts with the Baltic Countries during the Second World War

    Directory of Open Access Journals (Sweden)

    Timo Salminen

    2015-10-01

    Full Text Available Finnish archaeologists, especially Aarne Michaël Tallgren, had established contacts with their colleagues in the Baltic countries before the Second World War. In the summer of 1939, the world situation became a dominant theme in letters between archaeologists. The outbreak of war in Europe and the military base negotiations in Moscow evoked increasing concern. After the Soviet attack on Finland, only a few Finnish and Baltic archaeologists stayed in contact, but communications revived quickly after the Finnish-Soviet peace treaty of 1940. Estonian archaeologist Harri Moora saw the trials of war as a punishment for forgetting all spiritual values in previous years. The Soviet occupation of the Baltic countries in 1940 broke all contacts for longer than a year. After Germany had occupied the Baltic countries in 1941 and was allied with Finland in war against the Soviet Union, connections could be resumed to some extent. Tallgren, together with the Swedish State Antiquarian Sigurd Curman, now started planning the evacuation of children from Estonia to Sweden. In 1942, scholarly discussion returned to the correspondence, although only on a practical level, but already in early 1943 all correspondence became impossible. At the same time, Finnish archaeologists were in contact with Baltic refugees, especially Francis Balodis from Latvia. There were also Scandinavian and British archaeologists with whom Finnish researchers exchanged information about colleagues in the Baltic countries. The communications mainly focused on three things: getting and spreading information regarding the current situation, offering both practical help and psychological support to colleagues in the Baltic countries, and attempting to re-establish the exchange of ideas within the scholarly community.

  11. Operation of Finnish nuclear power plants. Quarterly report, 2nd quarter 1996

    International Nuclear Information System (INIS)

    Sillanpaeae, T.

    1996-11-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants are also described. The report also includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants' production and load factors. In the second quarter of 1996, the Finnish nuclear power plant units were in power operation except for the annual maintenance outages of TVO plant units and the Midsummer shutdown at TVO II which was due to low electricity demand, a turbine generator inspection and repairs. The load factor average of all plant units was 88.9 %. Events in the second quarter of 1996 were classified level 0 on the International Nuclear Event Scale (INES)

  12. Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

    Science.gov (United States)

    Bustamante, Jacinta; Arias, Andres A; Vogt, Guillaume; Picard, Capucine; Galicia, Lizbeth Blancas; Prando, Carolina; Grant, Audrey V; Marchal, Christophe C; Hubeau, Marjorie; Chapgier, Ariane; de Beaucoudrey, Ludovic; Puel, Anne; Feinberg, Jacqueline; Valinetz, Ethan; Jannière, Lucile; Besse, Céline; Boland, Anne; Brisseau, Jean-Marie; Blanche, Stéphane; Lortholary, Olivier; Fieschi, Claire; Emile, Jean-François; Boisson-Dupuis, Stéphanie; Al-Muhsen, Saleh; Woda, Bruce; Newburger, Peter E; Condino-Neto, Antonio; Dinauer, Mary C; Abel, Laurent; Casanova, Jean-Laurent

    2011-01-01

    Germline mutations in CYBB, the human gene encoding the gp91phox subunit of the phagocyte NADPH oxidase, impair the respiratory burst of all types of phagocytes and result in X-linked chronic granulomatous disease (CGD). We report here two kindreds in which otherwise healthy male adults developed X-linked recessive Mendelian susceptibility to mycobacterial disease (MSMD) syndromes. These patients had previously unknown mutations in CYBB that resulted in an impaired respiratory burst in monocyte-derived macrophages but not in monocytes or granulocytes. The macrophage-specific functional consequences of the germline mutation resulted from cell-specific impairment in the assembly of the NADPH oxidase. This ‘experiment of nature’ indicates that CYBB is associated with MSMD and demonstrates that the respiratory burst in human macrophages is a crucial mechanism for protective immunity to tuberculous mycobacteria. PMID:21278736

  13. The Future of the Retail Advertising: Implications for the Finnish Newspaper Industry

    OpenAIRE

    FLINK, SOILE-MARI

    2011-01-01

    Starting point for this research was the future changes Internet will cause to Finnish newspaper economies. When evaluating the economic importance of future development to newspapers? economies, one of the most important areas is retail advertising and its shifting to online environment. So far Finnish retail advertising has been very much focused on printed newspapers and retailers? online investments have been moderate and conservative. The change is about to happen and this research answe...

  14. Visual impairment in Finnish Usher syndrome type III.

    Science.gov (United States)

    Plantinga, Rutger F; Pennings, Ronald J E; Huygen, Patrick L M; Sankila, Eeva-Marja; Tuppurainen, Kaija; Kleemola, Leenamaija; Cremers, Cor W R J; Deutman, August F

    2006-02-01

    To evaluate visual impairment in Finnish Usher syndrome type 3 (USH3) and compare this with visual impairment in Usher syndrome types 1b (USH1b) and 2a (USH2a). We carried out a retrospective study of 28 Finnish USH3 patients, 24 Dutch USH2a patients and 17 Dutch USH1b patients. Cross-sectional regression analyses of the functional acuity score (FAS), functional field score (FFS*) and functional vision score (FVS*) related to age were performed for all patients. The FFS* and FVS* were calculated using the isoptre V-4 test target instead of the usual III-4 target. Statistical tests relating to regression lines and Student's t-test were used to compare between USH3 patients and the other genetic subtypes of Usher syndrome. Cross-sectional analyses revealed significant deterioration in the FAS (1.3% per year), FFS* (1.4% per year) and FVS* (1.8% per year) with advancing age in the USH3 patient group. At a given age the USH3 patients showed significantly poorer visual field function than the USH2a patients. The rate of deterioration in visual function in Finnish USH3 patients was fairly similar to that in Dutch USH1b or USH2a patients. At a given age, visual field impairment in USH3 patients was similar to that in USH1b patients but poorer than in USH2a patients.

  15. Postcolonial Powers of Opposition in Octavia Butler’s Kindred

    Directory of Open Access Journals (Sweden)

    Thamer Amer JubouriAl_Ogaili

    2016-03-01

    Full Text Available This study will examine postcolonial powers of opposition in Octavia Butler’s Kindred (1979; through Homi Bhabha’s concept of ambivalence and Edward Said’s self-other relationship. By using these concepts, this research aims to unravel how the colonized and the colonizer perceive each in the selected works. It will offer an in-depth analysis of the thematic and ideological characteristics of selected works. Thus, the focus will mainly be on the theme of the mutual relationship between the colonized and the colonizer in the selected works. This relationship is specified to the concept of ambivalence. This concept incarnates the dual, yet, uncontrolled relationship between the colonized and the colonizer. Nevertheless, the colonized considers the colonizer as oppressive but an envious power; and the colonizer judges the colonized as inferior but indigenous. The colonial relationship will also be revealed by using the concept of self-other. Such concept scrutinizes the way the colonized and the colonizer perceive and resist each other. Accordingly, the research’s main focus point is the power relationship developed in the light of colonial ambivalence and self-other continuum. The research’s methodology relies on Bhabha’s concept of ambivalence and Edward Said’s self-other relationship.  In The Location of Culture (1994, Bhabha maintains that the concept of ambivalence conveys “the exercise of colonialist authority, however, requires the production of differentiations, individuations, identity effects through which discriminatory practices can map out subject populations that are tarred with the visible and transparent mark of power” (111. Edward Said, in his discussion of self-other relationship in Orientalism (1979, argues that self-other relationship is “the vacillation [inconstancy] between the familiar [self] and the alien [other]” (72.

  16. Rational use of energy. Finnish technology cases

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This publication has been produced within the THERMIE B project `Interactive Promotion of Energy Technologies between Finland and Other EUCountries and to Estonia` (STR-0622-95-FI) as carried out for DG XVII of the European Commission. MOTIVA of Finntech Finnish Technology Ltd Oy has acted as the project co-ordinating body, with Ekono B.E., Ekono Energy Ltd and Friedemann and Johnson Consultants GmbH as partners. The main aim of the second phase of the project, as documented here, was to produce a publication in English on Finnish energy technologies, primarily in the building, industry and traffic sectors. The target distribution for this publication is primarily the EU countries through public and commercial information networks. During the work, the latest information on Finnish energy technologies has been collected, reviewed, screened and analysed in relation to the THERMIE programme. The following presentation consists of descriptions of case technologies; their background, technical aspects and energy saving potentials where applicable. The three RUE sectors; buildings, industry and traffic, are put forward in separate chapters. The building sector concentrates mostly in different control systems. New lighting and heating systems increase energy savings both in the large industrial sites and in private homes. In the industry sector new enhanced processes are introduced along with new products to increase energy efficiency. Traffic sector concentrates in traffic control and reducing exhaust gas emissions by new systems and programmes. The aim in Finland is to reduce exhaust gas emissions both by controlling the traffic efficiently and by developing fuels with lower emission levels. A lot is being done by educating the drivers and the public in efficient driving methods

  17. Operation of Finnish nuclear power plants. Quarterly report, 3. quarter 1988

    International Nuclear Information System (INIS)

    Koponen, H.

    1989-02-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environment

  18. Operation of Finnish nuclear power plants. Quarterly report, 2. quarter 1988

    International Nuclear Information System (INIS)

    Koponen, H.

    1988-12-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel or the environement

  19. Operation of Finnish nuclear power plants. Quarterly report 3. quarter 1987

    International Nuclear Information System (INIS)

    Haenninen, R.

    1988-06-01

    This general review of the operation of the Finnish nuclear power plants concentrates on such events and discoveries related to nuclear and radiation safety as the regulatory body, the Finnish Centre for Radiation and Nuclear Safety, regards as noteworthy. The report also includes a summary of the radiation safety of the personnel and the environment, as well as tabulated data on the production and load factors of the plants. In the report period, no event essentially degraded plant safety nor posed a radiation hazard to the personnel o the environment

  20. Final disposal of spent nuclear fuel in the Finnish bedrock

    International Nuclear Information System (INIS)

    1992-12-01

    Teollisuuden Voima Oy (TVO) studies Finnish bedrock for the final disposal of the spent nuclear fuel from the Olkiluoto nuclear power plant. The study is in accordance with the decision in principle by Finnish government in 1983. The report is the summary of the preliminary site investigations carried out during the years 1987-1992. On the basis of these investigations a few areas will be selected for detailed site investigation. The characterization comprises five areas selected from the shortlist of potential candidate areas resulted in the earlier study during 1983-1985. Areas are located in different parts of Finland and they represent the main formations of the Finnish bedrock. Romuvaara area in Kuhmo and Veitsivaara area in Hyrynsalmi represent the Archean basement. Kivetty area in Konginkangas consists of mainly younger granitic rocks. Syyry in Sievi is located in transition area of Svecofennidic rocks and granitic rocks. Olkiluoto in Eurajoki represents migmatites in southern Finland. For the field investigations area-specific programs were planned and executed. The field investigations have comprised airborne survey by helicopter, geophysical surveys, geological mappings and samplings, deep and shallow core drillings, geophysical and hydrological borehole measurements and groundwater samplings

  1. Are Students Customers in Finnish Higher Education?

    Science.gov (United States)

    Vuori, Johanna

    2013-01-01

    This study examines Finnish higher education students' perceptions of whether students are customers, based on qualitative interview data. The article contributes to the discussion on students as customers by giving attention to students' own voices from a country where tuition fees are not generally collected. The data are presented and analysed…

  2. Finnish Students’ Engagement in Science Lessons

    Directory of Open Access Journals (Sweden)

    Janna Linnansaari

    2015-05-01

    Full Text Available The decreasing number of students who are engaged in science learning has been recognised as a problem. The pre-conditions of engagement and actual engagement were examined using a novel research method to obtain detailed information on Finnish students’ engagement in different situations and to gain a better understanding of this phenomenon. The study’s participants consisted of 68 students (31 girls, 37 boys from 9th grade and 67 students (46 girls, 21 boys from 1st grade in upper secondary school. The research aimed to answer the following question: How does Finnish students’ engagement occur in exact and life science lessons? Participants received smartphones equipped with a smartphone application that included an experience sampling method questionnaire. The smartphones were programmed to emit a signal during every science lesson and otherwise randomly during the day (from 8 am to 8 pm. The results reveal that situation and grade had significant effects on students’ pre-conditions of engagement and actual engagement. Our results also show that girls had the highest interest in life science lessons and boys in exact science lessons.

  3. Localization of A Novel Autosomal Recessive Non-Syndromic Hearing Impairment Locus (DFNB38) to 6q26–q27 in a Consanguineous Kindred from Pakistan

    OpenAIRE

    Ansar, Muhammad; Ramzan, Mohammad; Pham, Thanh L.; Yan, Kai; Jamal, Syed Muhammad; Haque, Sayedul; Ahmad, Wasim; Leal, Suzanne M.

    2003-01-01

    For autosomal recessive nonsyndromic hearing impairment over 30 loci have been mapped and 19 genes have been identified. DFNB38, a novel locus for autosomal recessive nonsyndromic hearing impairment, was localized in a consanguineous Pakistani kindred to 6q26–q27. The affected family members present with profound prelingual sensorineural hearing impairment and use sign language for communications. Linkage was established to microsatellite markers located on chromosome 6q26–q27 (Multipoint lod...

  4. Updated survey of Fusarium species and toxins in Finnish cereal grains.

    Science.gov (United States)

    Hietaniemi, Veli; Rämö, Sari; Yli-Mattila, Tapani; Jestoi, Marika; Peltonen, Sari; Kartio, Mirja; Sieviläinen, Elina; Koivisto, Tauno; Parikka, Päivi

    2016-05-01

    The aim of the project was to produce updated information during 2005-14 on the Fusarium species found in Finnish cereal grains, and the toxins produced by them, as the last comprehensive survey study of Fusarium species and their toxins in Finland was carried out at the turn of the 1960s and the 1970s. Another aim was to use the latest molecular and chemical methods to investigate the occurrence and correlation of Fusarium species and their mycotoxins in Finland. The most common Fusarium species found in Finland in the FinMyco project 2005 and 2006 were F. avenaceum, F. culmorum, F. graminearum, F. poae, F. sporotrichioides and F. langsethiae. F. avenaceum was the most dominant species in barley, spring wheat and oat samples. The occurrence of F. culmorum and F. graminearum was high in oats and barley. Infection by Fusarium fungi was the lowest in winter cereal grains. The incidence of Fusarium species in 2005 was much higher than in 2006 due to weather conditions. F. langsethiae has become much more common in Finland since 2001. F. graminearum has also risen in the order of importance. A highly significant correlation was found between Fusarium graminearum DNA and deoxynivalenol (DON) levels in Finnish oats, barley and wheat. When comparing the FinMyco data in 2005-06 with the results of the Finnish safety monitoring programme for 2005-14, spring cereals were noted as being more susceptible to infection by Fusarium fungi and the formation of toxins. The contents of T-2 and HT-2 toxins and the frequency of exceptionally high DON concentrations all increased in Finland during 2005-14. Beauvericin (BEA), enniatins (ENNs) and moniliformin (MON) were also very common contaminants of Finnish grains in 2005-06. Climate change is leading to warmer weather, and this may indicate more changes in Finnish Fusarium mycobiota and toxin contents and profiles in the near future.

  5. Mutational analysis of the HGO gene in Finnish alkaptonuria patients

    Science.gov (United States)

    de Bernabe, D. B.-V.; Peterson, P.; Luopajarvi, K.; Matintalo, P.; Alho, A.; Konttinen, Y.; Krohn, K.; de Cordoba, S. R.; Ranki, A.

    1999-01-01

    Alkaptonuria (AKU), the prototypic inborn error of metabolism, has recently been shown to be caused by loss of function mutations in the homogentisate-1,2-dioxygenase gene (HGO). So far 17 mutations have been characterised in AKU patients of different ethnic origin. We describe three novel mutations (R58fs, R330S, and H371R) and one common AKU mutation (M368V), detected by mutational and polymorphism analysis of the HGO gene in five Finnish AKU pedigrees. The three novel AKU mutations are most likely specific for the Finnish population and have originated recently.


Keywords: alkaptonuria; homogentisate-1,2-dioxygenase; Finland PMID:10594001

  6. Finnish psychiatry--past and present.

    Science.gov (United States)

    Pylkkänen, Kari

    2012-03-01

    The history of Finnish psychiatry has been characterized by polarizations: priority in hospitals vs. outpatient care, centralized vs. decentralized organization, independent vs. integrated administration, biological vs. psychological treatments, private vs. public production, special psychiatric policies vs. general health policies. The independent psychiatric organizations on District level lasted from the 1920s until 1990. Since then, the formerly independent psychiatry was subordinated to General Hospital administration and the centralized system of state planning and financing of healthcare was gradually decentralized and run down. During the heavy Finnish economic recession of the early 1990 s, the cuts of the public sector were unfortunately focused most heavily on psychiatric services. The main focus of research and teaching has shifted from earlier emphasis on psychoanalytical approach to biological psychiatry since the late 1980s. The administrative position of psychiatry has been repeatedly changing and unstable during the last 20 years. At the level of the contents of the services, however, there have been many very positive and promising developments. Psychiatry has come closer to other specialties from its formerly isolated position, when the separate administrations have been integrated. Provision of outpatient services has increased remarkably, while the number of hospital beds has decreased radically. Interest and resources in research have increased remarkably, and numerous new and good quality psychiatric research reports are being published.

  7. Why low doses at Finnish NPPs?

    International Nuclear Information System (INIS)

    Wahlstroem, B.; Vaehaemaa, T.

    1995-01-01

    The Finnish nuclear power units - two BWRs (ABB Atom) and two PWRs (VVER) -are known for their high load factors. Finland's reactors have topped the world ranking list for more than ten years. This explains why their collective radiation doses are among the lowest in the world. During normal operation a collective dose of less than ten millisieverts per month is received at one site

  8. A Comparison Between Denaturing Gradient Gel Electrophoresis and Denaturing High Performance Liquid Chromatography in Detecting Mutations in Genes Associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC and the Identification of 9 New Mutations Previously Unidentified by DGGE

    Directory of Open Access Journals (Sweden)

    Meldrum Cliff J

    2003-12-01

    Full Text Available Abstract Denaturing high performance liquid chromatography is a relatively new method by which heteroduplex structures formed during the PCR amplification of heterozygote samples can be rapidly identified. The use of this technology for mutation detection in hereditary non-polyposis colorectal cancer (HNPCC has the potential to appreciably shorten the time it takes to analyze genes associated with this disorder. Prior to acceptance of this method for screening genes associated with HNPCC, assessment of the reliability of this method should be performed. In this report we have compared mutation and polymorphism detection by denaturing gradient gel electrophoresis (DGGE with denaturing high performance liquid chromatography (DHPLC in a set of 130 families. All mutations/polymorphisms representing base substitutions, deletions, insertions and a 23 base pair inversion were detected by DHPLC whereas DGGE failed to identify four single base substitutions and a single base pair deletion. In addition, we show that DHPLC has been used for the identification of 5 different mutations in exon 7 of hMSH2 that could not be detected by DGGE. From this study we conclude that DHPLC is a more effective and rapid alternative to the detection of mutations in hMSH2 and hMLH1 with the same or better accuracy than DGGE. Furthermore, this technique offers opportunities for automation, which have not been realised for the majority of other methods of gene analysis.

  9. Finnish research programmes on nuclear power plant safety

    International Nuclear Information System (INIS)

    Puska, E. K.

    2010-01-01

    The current Finnish national research programme on nuclear power plant safety SAFIR2010 for the years 2007-2010 as well as the coming SAFIR2014 programme for the years 2011-2014 are based on the chapter 7a, 'Ensuring expertise', of the Finnish Nuclear Energy Act. The objective of this chapter is realised in the research work and education of experts in the projects of these research programmes. SAFIR2010 research programme is divided in eight research areas that are Organisation and human, Automation and control room, Fuel and reactor physics, Thermal hydraulics, Severe accidents, Structural safety of reactor circuit, Construction safety, and Probabilistic Safety Analysis (PSA). All the research areas include both projects in their own area and interdisciplinary co-operational projects. Research projects of the programme are chosen on the basis of annual call for proposals. In 2010 research is carried out in 33 projects in SAFIR2010. VTT is the responsible research organisation in 26 of these projects and VTT is also the coordination unit of SAFIR2010 and SAFIR2014. In 2007-2009 SAFIR2010 produced 497 Specified research results (Deliverables), 618 Publications, and 33 Academic degrees. SAFIR2010 programme covers approximately half of the reactor safety research volume in Finland currently. In 2010 the programme volume is EUR 7.1 million and 47 person years. The major funding partners are VYR with EUR 2.96 million, VTT with EUR 2.66 million, Fortum with EUR 0.28 million, TVO with EUR 0.19 million, NKS with EUR 0.15 million, EU with only EUR 0.03 million and other partners with EUR 0.85 million. The new decisions-in-principle on Olkiluoto unit 4 for Teollisuuden Voima and new nuclear power plant for Fennovoima ratified by the Finnish Parliament on 1 July 2010 increase the annual funding collected according to the Finnish Nuclear Energy Act from Fennovoima, Fortum and Teollisuuden Voima for the SAFIR2014 programme to EUR 5.2 million from the current level of EUR 3

  10. The Finnish research programme on climate change. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Roos, J [ed.

    1997-12-31

    This is the final report of the Finnish Research Programme on Climate Change (SILMU). This report includes the final results and conclusions made by the individual research groups. The aim of this report is to lay out the research work, and to present the main results and conclusions obtained during the six-year work. The Finnish Research Programme on Climate Change (SILMU) was a multidisciplinary national research programme on climate and global change. The principal goals of SILMU were: (1) to increase our knowledge on climate change, its causes, mechanisms and consequences, (2) to strengthen the research on climate change in Finland, (3) to increase the participation of Finnish researchers in international research programmes, and (4) to prepare and disseminate information for policy makers on adaptation and mitigation. The key areas of the research were: (1) quantification of the greenhouse effect and the magnitude of anticipated climatic changes,(2) assessment of the effects of changing climate on ecosystems, and (3) development of mitigation and adaptation strategies. The research programme started in June 1990, and it comprised more than 80 individual research projects, ranging from atmospheric chemistry to economics. There were approximately two hundred scientists working within the programme in seven universities and eleven research institutions. The research activities that comprise SILMU were grouped into four interdisciplinary subprogrammes: atmosphere, waters, terrestrial ecosystems and integration and human interactions

  11. The Finnish research programme on climate change. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Roos, J. [ed.

    1996-12-31

    This is the final report of the Finnish Research Programme on Climate Change (SILMU). This report includes the final results and conclusions made by the individual research groups. The aim of this report is to lay out the research work, and to present the main results and conclusions obtained during the six-year work. The Finnish Research Programme on Climate Change (SILMU) was a multidisciplinary national research programme on climate and global change. The principal goals of SILMU were: (1) to increase our knowledge on climate change, its causes, mechanisms and consequences, (2) to strengthen the research on climate change in Finland, (3) to increase the participation of Finnish researchers in international research programmes, and (4) to prepare and disseminate information for policy makers on adaptation and mitigation. The key areas of the research were: (1) quantification of the greenhouse effect and the magnitude of anticipated climatic changes,(2) assessment of the effects of changing climate on ecosystems, and (3) development of mitigation and adaptation strategies. The research programme started in June 1990, and it comprised more than 80 individual research projects, ranging from atmospheric chemistry to economics. There were approximately two hundred scientists working within the programme in seven universities and eleven research institutions. The research activities that comprise SILMU were grouped into four interdisciplinary subprogrammes: atmosphere, waters, terrestrial ecosystems and integration and human interactions

  12. Operation of Finnish nuclear power plants. Quarterly report 3rd quarter, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    1995-03-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe nuclear and radiation safety related events and observations which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants and general matters relating to the use of nuclear energy are also reported. A summary of the radiation safety of plant personnel and of the environment, and tabulated data on the plants` production and load factors are also given. (4 figs., 4 tabs.).

  13. Operation of Finnish nuclear power plants. Quarterly report 3rd quarter, 1994

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1995-03-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe nuclear and radiation safety related events and observations which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants and general matters relating to the use of nuclear energy are also reported. A summary of the radiation safety of plant personnel and of the environment, and tabulated data on the plants' production and load factors are also given. (4 figs., 4 tabs.)

  14. Evaluation of the Finnish nuclear waste management programme

    International Nuclear Information System (INIS)

    1994-05-01

    In response to a request from Finland in November 1992, the International Atomic Energy Agency (IAEA) set up a Team of four experts (representatives from Belgium, Canada, Germany and Switzerland) to review the Finnish nuclear waste management programme within the auspices of IAEA's Waste Management programme (WATRP). During the early summer of 1993, the Team reviewed a large amount of documentation supplied by the Finnish industry, government and research organizations. The radioactive waste management programme areas within the Team's terms of reference included: (1) work being done in siting and building a conditional facility for spent nuclear fuel and siting and constructing a co-located repository, (2) the plans and activities for conditioning and disposing of the low and intermediate level waste from Finland's NPPs and (3) the plans for decommissioning Finland's reactors when that becomes necessary. The evaluation work and the recommendations of the Team are detailed in the report

  15. The key elements for genetic response in Finnish dairy cattle breeding

    Directory of Open Access Journals (Sweden)

    Jarmo Juga

    1998-01-01

    Full Text Available This paper reviews some key elements of Finnish animal breeding research contributing to the Finnish dairy cattle breeding programme and discusses the possibilities and problems in collecting data for genetic evaluation, prediction of breeding values both within and across countries, estimation of the economic value of important traits, and selection of bulls and cows. Economic values are calculated for fertility, udder health and production traits when one genetic standard deviation unit (gen. sd. is changed in each trait independently and the financial returns from selection response in the Finnish dairy cattle breeding programme are estimated. The following components were used to calculate the economic value of mastitis treatments: 1 cost of mastitis including discarded milk and treatment costs, 2 reduction in milk price due to higher somatic cell count, 3 replacement costs and 4 lower production level of the herd due to involuntary culling of cows because of udder problems. A high somatic cell count lowers the price of milk and eventually leads to involuntary culling. For treatments for fertility disorders the following costs were included: 1 treatment costs 2 higher replacement costs and 3 decreased milk production in the herd. Days open included the following costs: 1 extra insemination, 2 reduced annual milk yield and 3 fewer calves born. Animal breeding was found to be a very cost effective investment, yielding returns of FIM 876.9 per cow from one round of selection when the gene flow was followed for over 25 years in the Finnish dairy cattle breeding programme.

  16. Finnish Higher Education Expansion and Regional Policy

    Science.gov (United States)

    Saarivirta, Toni

    2010-01-01

    This paper concentrates on the expansion of Finnish higher education between the 1960s and 1970s, exposes its background in the light of the policy decisions that were made, compares the unique features of this expansion with those of certain other countries, discusses the impact of the controlled "top down" governance of higher…

  17. Individualized Sex Equality in Transforming Finnish Academia

    Science.gov (United States)

    Lätti, Johanna

    2017-01-01

    This article examines the equality agenda in the context of Finnish university reform in the 21st century. In Finland, the academic regime went through an organizational transformation after the Universities Act in 2009. However, little attention has been paid to the questions of sex or equality. Since the policy influences on equality in…

  18. Operation of Finnish nuclear power plants. Quarterly report 3rd, quarter 1995

    International Nuclear Information System (INIS)

    Sillanpaeae, T.

    1996-05-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants are also described. The Report includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants' production and load factors. Except for the annual maintenance outages of Loviisa plant units and for TVO II's brief outage to repair a failed component, Finnish nuclear power plant units were in power operation in the third quarter of 1995. The load factor average of all plant units was 90.4 %. Events in this quarter were level 0 on the INES scale. Occupational doses and radioactive releases off-site were below authorised limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.) (4 figs., 4 tabs.)

  19. Orofacial pain and symptoms of temporomandibular disorders in Finnish and Thai populations.

    Science.gov (United States)

    Sipilä, Kirsi; Tolvanen, Mimmi; Mitrirattanakul, Somsak; Sitthisomwong, Panupen; Järvelin, Marjo-Riitta; Taanila, Anja; Anttonen, Vuokko; Lahti, Satu

    2015-07-01

    Cultural or ethnic factors may play an important role in subjects' pain reports. The aim of the study was to compare the prevalence of orofacial pain symptoms between Finnish and Thai populations. The Finnish study population comprised the Northern Finland Birth Cohort 1966, of which 5696 subjects participated in the present study. The Thai sample consisted of 1501 randomly selected people living in 10 different districts in Bangkok. Data on orofacial pain was collected based on questionnaires. After adjusting for age, gender and education, the logistic regression analysis showed that Thai subjects had an increased risk for reporting oral pain (OR = 4.5, 95% CI = 3.7-5.4), tooth pain (OR = 2.0, 95% CI = 1.8-2.4) and pain in the face (OR = 1.5, 95% CI = 1.2-1.7). It can be concluded that Thai people report more orofacial pain symptoms than Finnish subjects. Cross-cultural factors exist in the background of reporting pain symptoms in the oral and facial area.

  20. Operation of Finnish nuclear power plants. Quarterly report 3rd, quarter 1995

    Energy Technology Data Exchange (ETDEWEB)

    Sillanpaeae, T [ed.

    1996-05-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants are also described. The Report includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants` production and load factors. Except for the annual maintenance outages of Loviisa plant units and for TVO II`s brief outage to repair a failed component, Finnish nuclear power plant units were in power operation in the third quarter of 1995. The load factor average of all plant units was 90.4 %. Events in this quarter were level 0 on the INES scale. Occupational doses and radioactive releases off-site were below authorised limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.) (4 figs., 4 tabs.).

  1. Excess mortality in winter in Finnish intensive care.

    Science.gov (United States)

    Reinikainen, M; Uusaro, A; Ruokonen, E; Niskanen, M

    2006-07-01

    In the general population, mortality from acute myocardial infarctions, strokes and respiratory causes is increased in winter. The winter climate in Finland is harsh. The aim of this study was to find out whether there are seasonal variations in mortality rates in Finnish intensive care units (ICUs). We analysed data on 31,040 patients treated in 18 Finnish ICUs. We measured severity of illness with acute physiology and chronic health evaluation II (APACHE II) scores and intensity of care with therapeutic intervention scoring system (TISS) scores. We assessed mortality rates in different months and seasons and used logistic regression analysis to test the independent effect of various seasons on hospital mortality. We defined 'winter' as the period from December to February, inclusive. The crude hospital mortality rate was 17.9% in winter and 16.4% in non-winter, P = 0.003. Even after adjustment for case mix, winter season was an independent risk factor for increased hospital mortality (adjusted odds ratio 1.13, 95% confidence interval 1.04-1.22, P = 0.005). In particular, the risk of respiratory failure was increased in winter. Crude hospital mortality was increased during the main holiday season in July. However, the severity of illness-adjusted risk of death was not higher in July than in other months. An increase in the mean daily TISS score was an independent predictor of increased hospital mortality. Severity of illness-adjusted hospital mortality for Finnish ICU patients is higher in winter than in other seasons.

  2. Establishing a culturally specific nursing home for Finnish-speaking older persons in Sweden: A case study.

    Science.gov (United States)

    Hadziabdic, Emina; Hjelm, Katarina

    2018-04-01

    The study aims to describe the establishment of a culturally specific nursing home for Finnish-speaking older persons in Sweden. A descriptive qualitative study. A descriptive case study based on a review of 14 public documents and individual interviews with two experts in the area, analysed with qualitative content analysis. This study found that shared language, preservation of customs and habits and collaboration between the representatives of the municipality, Finnish-speaking migrant associations and staff at the nursing home influenced the development of the culturally specific nursing home for older Finnish-speaking people intended to avoid loneliness, isolation and misunderstandings among older Finnish-speaking. Collaboration between healthcare service for older persons and minority people resulted in an optimal culturally specific nursing home, simultaneously encountering the majority culture. Nursing and healthcare services need to be aware of positive effects of collaboration with stakeholders to achieve optimal culturally specific nursing homes.

  3. Work Ability of Finnish Physical Education Teachers

    Science.gov (United States)

    Mäkelä, Kasper; Hirvensalo, Mirja

    2015-01-01

    In the physical education (PE) teachers' profession, physical tasks comprise a large part of the job. PE teachers identify their health as good, and they are satisfied with their job. Nevertheless, the work ability of PE teachers may be decreasing. Purpose: The purpose of this article was to explore the work ability of Finnish PE teachers. What…

  4. Background information for NDT qualification of Finnish disposal canisters of spent fuel

    International Nuclear Information System (INIS)

    Sarkimo, M.; Pitkaenen, J.

    2013-12-01

    This report presents a review to basic concepts, which are applied in the qualification of non-destructive testing (NDT) techniques. The qualification systems developed and used in some countries are briefly described in the beginning of the report. Anyway the report mainly discusses the qualification practices applied in the Finnish nuclear industry. The Finnish Radiation and Nuclear Safety Authority (STUK) in the YVL Guide 3.8 define the Finnish qualification approach applied for the in-service inspections. The principles presented in this document follow the views of the international organisations: Nuclear Regulator Working Group (NRWG) and European Network for Inspection and Qualification (ENIQ). For the practical qualification work a national guideline is established using so called SP-documents that include specific rules and instructions for execution of qualifications in accordance with YVL Guide 3.8 principles. Altogether the Finnish qualification system can be seen very well to follow the European (ENIQ) methodology. The report discusses several qualification terms and documents. Thus the normally necessary tasks and parts of a qualification are described. The qualification can be seen as a project that includes several tasks, which will be performed by different parties. Enough resources and time should be reserved for the planning and control of a qualification project to ensure its fluent progress. Some tasks are discussed in the report taking into account the situation in the qualification cases that are seen to be linked to the inspections of disposal canisters of spent fuel. (orig.)

  5. Background information for NDT qualification of Finnish disposal canisters of spent fuel

    Energy Technology Data Exchange (ETDEWEB)

    Sarkimo, M. [VTT Technical Research Centre of Finland, Espoo (Finland); Pitkaenen, J.

    2013-12-15

    This report presents a review to basic concepts, which are applied in the qualification of non-destructive testing (NDT) techniques. The qualification systems developed and used in some countries are briefly described in the beginning of the report. Anyway the report mainly discusses the qualification practices applied in the Finnish nuclear industry. The Finnish Radiation and Nuclear Safety Authority (STUK) in the YVL Guide 3.8 define the Finnish qualification approach applied for the in-service inspections. The principles presented in this document follow the views of the international organisations: Nuclear Regulator Working Group (NRWG) and European Network for Inspection and Qualification (ENIQ). For the practical qualification work a national guideline is established using so called SP-documents that include specific rules and instructions for execution of qualifications in accordance with YVL Guide 3.8 principles. Altogether the Finnish qualification system can be seen very well to follow the European (ENIQ) methodology. The report discusses several qualification terms and documents. Thus the normally necessary tasks and parts of a qualification are described. The qualification can be seen as a project that includes several tasks, which will be performed by different parties. Enough resources and time should be reserved for the planning and control of a qualification project to ensure its fluent progress. Some tasks are discussed in the report taking into account the situation in the qualification cases that are seen to be linked to the inspections of disposal canisters of spent fuel. (orig.)

  6. Reliability and validity study of the Finnish version 2.0 of the oswestry disability index.

    Science.gov (United States)

    Pekkanen, Liisa; Kautiainen, Hannu; Ylinen, Jari; Salo, Petri; Häkkinen, Arja

    2011-02-15

    Prospective clinical validation study. The aims of this study were to translate into Finnish and culturally adapt and study the psycho-metric properties of the Oswestry Disability Index (ODI) version 2.0. The ODI is one of the most commonly reported back-specific disability questionnaires. It is widely used both in clinical work and in medical studies. To date, no validated Finnish version of the ODI version 2.0 has been reported. The ODI version 2.0 was translated into the Finnish language. A total of 115 patients with back pain, referred by the primary care physician to the outpatient clinic of the department of physical medicine and rehabilitation, were recruited for this study. The patients answered a questionnaire package that included the Finnish ODI 2.0, Back Pain Questionnaire for Visual Analogue Assessment (Million-VAS), Visual Analogue Scales of back and leg pain (VASback, VASleg), the Depressions Scale, and a question on their subjectively perceived health. The package was administered twice; 2 weeks before and at the arrival to the clinic. Reproducibility of the ODI was 0.90 (95% confidence interval [CI] = 0.85-0.94) and the internal consistency was 0.86 (95% CI = 0.81-0.90). Factor analysis showed that the ODI was loaded on 2 factors, which explained 51% of the total variance. In testing convergent validity ODI correlated with Million-VAS, r = 0.75 (95% CI = 0.64-0.84); VASback, r = 0.48 (95% CI = 0.32-0.62); and VAS leg, r = 0.41 (95% CI = 0.23-0.57). The Finnish ODI version 2.0 proved to be a valid and reliable instrument that showed psychometric properties comparable with the original English version. Therefore, it can be used in assessing the disability among Finnish-speaking patients with back pain for both clinical and scientific purposes.

  7. MARKETING STRATEGY FOR THE FINNISH TOURIST COMPANY BASED ON SAINT PETERSBURG MARKET RESEARCH

    OpenAIRE

    Miroshnichenko, Julia

    2014-01-01

    The goal of this thesis is to get a marketing strategy for proposed tourist business through the field-work marketing research. The purpose of this marketing research was to investigate the attitudes of Russian tourists in Saint Pe-tersburg towards Finland as a destination. The research examines the respondents’ own evaluation of the Finnish tourism possibilities, as well as the expert evaluation (made by the professionals of tourist agencies in Saint Petersburg) of the Finnish tourist ma...

  8. Open source in Finnish software companies

    OpenAIRE

    Seppä, Arto

    2006-01-01

    This paper explores survey data focusing on open source software supply collected from 170 Finnish software firms using descriptive statistical analysis. The first half of the report contains general data about software companies and the differences between proprietary and open source firms. The second half focuses on open source firms. A subject of analysis are copyrights, products and services supply, the firms’ relationships with the open source community, and their views on opportunities ...

  9. The 1993 Finnish Interdisciplinary Seminar on SETI - A review of aims, approaches and conclusions

    Science.gov (United States)

    Seppanen, Jouko

    1993-10-01

    The communications of the International Interdisciplinary Seminar on SETI, held on March 6-7, 1993 in Vantaa, Finland, are reviewed and the contents and conclusions of papers summarized. The seminar was organized jointly by the Finnish Artificial Intelligence Society (FAIS), Finnish Astronomical Society, Ursa Astronomical Association and Heureka - The Finnish Science Centre. As the ninth in a series of intelligence-related seminars of FAIS, SETI was chosen as the topic for spring 1993, noting the new ten year NASA SETI program HRMS (High Resolution Micro-wave Survey), commenced on Columbus Day, October 12, 1992. The aims and the interdisciplinary format of the seminar are described, the main results and conclusions of papers are restated, and the seminar publications introduced. The summaries of papers are based on their abstracts and contain excerpts from texts.

  10. Independent Induction of Caspase-8 and cFLIP Expression during Colorectal Carcinogenesis in Sporadic and HNPCC Adenomas and Carcinomas

    Directory of Open Access Journals (Sweden)

    D. M. Heijink

    2007-01-01

    Full Text Available Background: TNF-Related Apoptosis Inducing Ligand (TRAIL is a promising agent for the induction of apoptosis in neoplastic tissues. Important determinants of TRAIL sensitivity are two intracellular proteins of the TRAIL pathway, caspase-8 and its anti-apoptotic competitor cellular Flice-Like Inhibitory Protein (cFLIP. Methods: The aim of this study was to investigate basic expression of caspase-8 and cFLIP in normal colorectal epithelium (n = 20, colorectal adenomas (n = 66 and colorectal carcinomas (n = 44 using immunohistochemistry performed on both sporadic and Hereditary Non-Polyposis Colorectal Cancer (HNPCC or Lynch syndrome-associated adenomas and carcinomas. Results: Expression of both caspase-8 and cFLIP was similar in cases with sporadic and hereditary origin. Expression of caspase-8 in colorectal adenomas and carcinomas was increased when compared to normal colon tissue (P = 0.02. Nuclear, paranuclear as well as cytoplasmic localizations of caspase-8 were detected. Immunohistochemistry revealed an upregulation of cFLIP in colorectal carcinomas in comparison to normal epithelium and colorectal adenomas (P < 0.001. A large variation in the caspase-8/cFLIP ratio was observed between the individual adenomas and carcinomas. Conclusion: Caspase-8 and cFLIP are upregulated during colorectal carcinogenesis. Upregulation of caspase-8 and/or downregulation of cFLIP may be interesting approaches to maximize TRAIL sensitivity in colorectal neoplasms.

  11. Romance Tourism and Finnish Women

    OpenAIRE

    Jussila, Johanna

    2015-01-01

    Romance tourism is a discussed quite a lot in media both in Finland and abroad. The media has create a certain kind of image of women`s romance tourism. The main aim of this study was to study how Finnish women perceive the romance tourism. The research questions were: does women travel to abroad to seek for holiday romance and why do they travel to abroad to seek for the romance. To find out women’s mental images of romance tourism was also one aim of the research. The phenomenon of women’s ...

  12. The SKVR Database of Ancient Poems of the Finnish People in Kalevala Meter and the Semantic Kalevala

    Directory of Open Access Journals (Sweden)

    Lauri Harvilahti

    2013-10-01

    Full Text Available This essay presents the principal aims of establishing a web-based infrastructure for epic research and demonstrates possibilities for using this infrastructure for textual research on epics. The web infrastructure discussed here has developed out of the Finnish Literature Society’s pioneering open-access digitized edition of Kalevala-meter poetry Suomen Kansan Vanhat Runot (“The Ancient Poems of the Finnish People”; 34 volumes, SKVR and the Semantic Kalevala, an electronic indexing of the Finnish national epic Kalevala that uses the Culture Sampo web portal.

  13. Reference values of inspiratory spirometry for Finnish adults.

    Science.gov (United States)

    Kainu, Annette; Timonen, Kirsi L; Vanninen, Esko; Sovijärvi, Anssi R

    2018-03-07

    Inspiratory spirometry is used in evaluation of upper airway disorders e.g. fixed or variable obstruction. There are, however, very few published data on normal values for inspiratory spirometry. The main aim of this study was to produce reference values for inspiratory spirometry for healthy Finnish adults. Inspiratory spirometry was preplanned to a sample of the Finnish spirometry reference values sample. Data was successfully retrieved from 368 healthy nonsmoking adults (132 males) between 19 and 83 years of age. Reference equations were produced for forced inspiratory vital capacity (FIVC), forced inspiratory volume in one second (FIV1), FIV1/FIVC, peak inspiratory flow (PIF) and the ratios of FIV1/forced expiratory volume in one second and PIF/peak expiratory flow. The present values were compared to PIF values from previously used Finnish study of Viljanen et al. (1982) reference values and Norwegian values for FIV1, FIVC and FIV1/FIVC presented by Gulsvik et al. (2001). The predicted values from the Gulsvik et al. (2001), provided a good fit for FIVC, but smaller values for FIV1 with mean 108.3 and 109.1% of predicted values for males and females, respectively. PIF values were 87.4 and 91.2% of Viljanen et al. (1982) predicted values in males and females, respectively. Differences in measurement methods and selection of results may contribute to the observed differences. Inspiratory spirometry is technically more demanding and needs repeatability criteria to improve validity. New reference values are suggested to clinical use in Finland when assessing inspiratory spirometry. Utility of inspiratory to expiratory values indices in assessment of airway collapse need further study.

  14. Airborne fallout mapping of 137Cs Finnish defence forces team

    International Nuclear Information System (INIS)

    Kettunen, M.; Heininen, T.; Pulakka, M.

    1997-01-01

    The main task of the team was to create a fallout map of 137 Cs in a specified area in Padasjoki Auttoinen village. The team used an MI-8 helicopter of the Finnish Air Force. The team had an HPGe system (relative efficiency 70%) to measure nuclide specific ground contamination level. For navigation the team took advantage of the DGPS service provided by Finnish Broadcasting company utilizing the RDS-channel to get position accuracy within 2 meters. The correction signal is reachable nationwide on the FM transmitter network. The system produced a distribution map for 40 K and fallout maps for 134,137 Cs using a Micro Station Program with TerraModeler application. The maximum measured 137 Cs ground contamination exceeded 130-140 kBqm -2 . (au)

  15. Implications of the Bologna Process for Throughput in the Higher Education Sector: An Empirical Illustration Based on a Finnish-British Comparison

    Science.gov (United States)

    Lindberg, Matti

    2014-01-01

    This study illustrates the differences between Finnish and British graduates in the higher education-to-work transition and related market mechanisms in the year 2000. Specifically, the differences between the Finnish and British students' academic careers and ability to find employment after graduation were evaluated in relation to the Finnish HE…

  16. Operation of Finnish nuclear power plants. Quarterly report, 4th quarter 1996

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1997-05-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants are also described. The report also includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants's production and load factors. In the fourth quarter of 1996, the Finnish nuclear power plant units were in power operation except for the annual maintenance outage of Loviisa 2 and a shutdown at Olkiluoto 1 to repair a condensate system stop valve. The load factor average of all plant units was 96.5%. Events in the fourth quarter of 1996 were level 0 on the International Nuclear Event Scale. Occupational doses and radioactive releases off-site were below authorised limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.)

  17. Operation of Finnish nuclear power plants. Quarterly report, 2nd quarter, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K. [ed.

    1995-10-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Fasety improvements at the plants are also described. The report includes a summary of the radiation safety of plant personnel and of the evironment and tabulated data on the plants` production and load factors. Except for the annual maintenance outages of the TVO plant units and for TVO II`s Midsummer outage which was due to low electricity demand, the Finnish nuclear power plants were in power operation during the second quarter of 1995. The load factor average of all four plant units was 91.2 %. Events during the second annual quarter were level 0 on the INES scale. Occupational doses and radioactive releases off-site were below authorized limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (4 figs., 4 tabs.).

  18. Finnish HLW disposal programme : site selection in 2000

    International Nuclear Information System (INIS)

    Ryhsnen, Veijo

    1997-01-01

    This paper covers the technical concepts for final disposal in the Finnish geological conditions, the approach for site selection and implementation, the safety assessments and development of criteria, the environmental impact assessment, the licensing stages and acceptance, and the financial provisions, the project organization in 1997 - 2000. 2 refs., 9 figs

  19. Finnish HLW disposal programme : site selection in 2000

    Energy Technology Data Exchange (ETDEWEB)

    Ryhsnen, Veijo [Posiva Oy, Helsinki (Finland)

    1997-12-31

    This paper covers the technical concepts for final disposal in the Finnish geological conditions, the approach for site selection and implementation, the safety assessments and development of criteria, the environmental impact assessment, the licensing stages and acceptance, and the financial provisions, the project organization in 1997 - 2000. 2 refs., 9 figs.

  20. Genome-Wide Meta-Analysis of Sciatica in Finnish Population.

    Directory of Open Access Journals (Sweden)

    Susanna Lemmelä

    Full Text Available Sciatica or the sciatic syndrome is a common and often disabling low back disorder in the working-age population. It has a relatively high heritability but poorly understood molecular mechanisms. The Finnish population is a genetic isolate where small founder population and bottleneck events have led to enrichment of certain rare and low frequency variants. We performed here the first genome-wide association (GWAS and meta-analysis of sciatica. The meta-analysis was conducted across two GWAS covering 291 Finnish sciatica cases and 3671 controls genotyped and imputed at 7.7 million autosomal variants. The most promising loci (p<1x10-6 were replicated in 776 Finnish sciatica patients and 18,489 controls. We identified five intragenic variants, with relatively low frequencies, at two novel loci associated with sciatica at genome-wide significance. These included chr9:14344410:I (rs71321981 at 9p22.3 (NFIB gene; p = 1.30x10-8, MAF = 0.08 and four variants at 15q21.2: rs145901849, rs80035109, rs190200374 and rs117458827 (MYO5A; p = 1.34x10-8, MAF = 0.06; p = 2.32x10-8, MAF = 0.07; p = 3.85x10-8, MAF = 0.06; p = 4.78x10-8, MAF = 0.07, respectively. The most significant association in the meta-analysis, a single base insertion rs71321981 within the regulatory region of the transcription factor NFIB, replicated in an independent Finnish population sample (p = 0.04. Despite identifying 15q21.2 as a promising locus, we were not able to replicate it. It was differentiated; the lead variants within 15q21.2 were more frequent in Finland (6-7% than in other European populations (1-2%. Imputation accuracies of the three significantly associated variants (chr9:14344410:I, rs190200374, and rs80035109 were validated by genotyping. In summary, our results suggest a novel locus, 9p22.3 (NFIB, which may be involved in susceptibility to sciatica. In addition, another locus, 15q21.2, emerged as a promising one, but failed to replicate.

  1. Distributed leadership in Finnish and Shanghai schools

    OpenAIRE

    Tian, Meng

    2016-01-01

    The present research employed mixed-methods approach to further theorise distributed leadership and to investigate its manifestations in Finnish and Shanghai schools. The whole research comprised two phases. The first phase contained a meta-analysis (Sub-study I), which systematically reviewed 85 key distributed leadership articles published between 2002 and 2013. The meta-analysis identified two main research paradigms: the descriptive-analytical paradigm and the prescrip...

  2. Chinese and Finnish Undergraduates’ Online Shopping Behaviour

    OpenAIRE

    Wan, Ning

    2015-01-01

    The main goal of the thesis was to recognise similar and different characteristics of online shopping behaviour between Chinese and Finnish undergraduates. Additionally, this thesis would give meaningful proposals for merchants and managers on offering better online marketing. This thesis report was conducted in both theoretical and practical parts. The theoretical parts include marketing research and online shopping consumption behaviour. The study describes the marketing research progre...

  3. International risk factors affecting Finnish energy supplies. Suomen energiahuollon kansainvaeliset uhkatekijaet

    Energy Technology Data Exchange (ETDEWEB)

    Kasanen, P.; Koponen, M.; Kaekoenen, J. (Oulu Univ., Oulu (Finland). Dept. of Geography)

    1989-01-01

    An examination is made of the structure and development of Finnish fuel imports, world fuel market trends and prospects, and the impact of global environmental concerns on Finnish energy supplies. Attention is focused on the political and economic developments to be expected in the major fuel producing or consuming countries. The aim is to look for factors that could treaten the functioning of Finnish fuel supplies and to suggest ways to avoid or overcome these threats. The research is based on Finnish and international energy statistics, published forecasts for the development of the fuel trade and fuel resources and the latest literature on energy economics and political science. Finland is heavily dependent on foreign fuels, over two thirds of her fuels supply being imported. By far the most important source of imports is the Soviet Union, although Poland is a major supplier of coal. The increase in domestic demands for fuels in these countries, will make it necessary for Finland to diversify the sources of her fuel imports. The suggestions made here include the following: Saudi-Arabia and Kuwait should be considered as possible new sources of oil. Coal could be imported from South Africa, provided that the apartheid policy is discontinued. Norway could provide some natural gas, although a Nordic pipeline system would be needed for this to be possible. Finland should invest in fuel resource exploration and development and in building the necessary infrastructure in the producing countries in order to improve the possibilities for reaching long-term agreements on fuel imports. Imporovements in the effiency of the end users of energy and an increase in the proportion of renewable sources of energy would not only be steps towards a sustainable fuel economy, but would also reduce the country's dependence on imported fuels.

  4. Studies of potential severe accidents in Finnish nuclear power plants. Quarterly report 3. quarter 1987

    International Nuclear Information System (INIS)

    Aro, Ilari.

    1989-07-01

    This thesis is based on six publications dealing with severe accident studies in Finnish nuclear power plants. Main emphasis has been put on general technical bases and methodologies applied in severe accident evaluation in Finland. As an example of the use of the analysis and evaluation methods, the analysis of one representative accident sequence, t otal loss of AC power , has been presented for both Finnish power plant types. This accident sequence is required to be analyzed in the Finnish safety guide YVL 2.2 which deals with transient and accident analyses as a basis of technical solutions at nuclear powr plants. Two different analysis methods, MAAP 3.0 and MARCH 3/STCP have been used for receiving as complete a picture as possible of the flow of events and for verifying the models to some extent. Besides the use of the two different models, the method of sensitivity analysis has been used for evaluating the effects of some important technical parameters on the accident flow. Finally, conclusions of the applicability of the two methods for analyzing severe accident sequences in Finnish plants have been discussed

  5. Apolipoprotein C-II and C-III metabolism in a kindred of familial hypobetalipoproteinemia

    International Nuclear Information System (INIS)

    Malmendier, C.L.; Delcroix, C.; Lontie, J.F.; Dubois, D.Y.

    1991-01-01

    Three affected members of a kindred with asymptomatic hypobetalipoproteinemia (HBL) showed low levels of triglycerides, low-density lipoprotein (LDL)-cholesterol, and apolipoproteins (apo) B, C-II, and C-III. Turnover of iodine-labeled apo C-II and apo C-III associated in vitro to plasma lipoproteins was studied after intravenous injection. Radioactivity in plasma and lipoproteins (95% recovered in high-density lipoprotein [HDL] density range) and in 24-hour urine samples was observed for 16 days. A parallelism of the slowest slopes of plasma decay curves was observed between apo C-II and apo C-III, indicating a partial common catabolic route. Urine/plasma radioactivity ratio (U/P) varied with time, suggesting heterogeneity of metabolic pathways. A new compartmental model using the SAAM program was built, not only fitting simultaneously plasma and urine data, but also taking into account the partial common metabolism of lipoprotein particles (LP) containing apo C-II and apo C-III. The low apo C-II and C-III plasma concentrations observed in HBL compared with normal resulted from both an increased catabolism and a reduced synthesis, these changes being more marked for apo C-III. The modifications in the rate constants of the different pathways calculated from the new model are in favor of an increased direct removal of particles following the fast pathway, likely in the very-low-density lipoprotein (VLDL) density range

  6. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1990-12-01

    During the second quarter of 1990 the Finnish nuclear plant units Loviisa 1 and 2 and TVO and II were in commercial operation for most of the time. The feedwater pipe rupture at Loviisa 1 and the resulting inspections and repairs at both Loviisa plant units brought about an outage the overall duration of which was 32 days. The annual maintenance outages of the TVO plant units were arranged during the report period and their combined duration was 31.5 days. Nuclear electricity accounted for 35.3% of the total Finnish electricity production during this quarter. The load factor average of the nuclear power plant units was 83.0%. Three events occurred during the report period which are classified as Level 1 on the International Nuclear Event Scale: feedwater pipe rupture at Loviisa 1, control rod withdrawal at TVO I in a test during an outage when the hydraulic scram system was rendered inoperable and erroneous fuel bundle transfers during control rod drives maintenance at TVO II. Other events during this quarter are classified as Level Zero (Below Scale) on the International Nuclear Event Scale. Occupational radiation doses and external releases of radioactivity were considerably below authorised limits. Only small amounts of nuclides originating in nuclear power plants were detected in samples taken in the vicinity of nuclear power plants

  7. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1993-12-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations related to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety considers safety significant. Safety-enhancing plant modifications and general matters relating to the use of nuclear energy are also reported. A summary of the radiation safety of plant personnel and the environment, and tabulated data on the plants' production and their load factors are also given. At the Loviisa 1 plant unit one of two specially-backed AC busbars was lost during the second quarter of 1993. A ca. 30 minute voltage break caused malfunctions in the plant unit's electrical equipment and rendered inoperable certain components important to safety. The event is rated on the International Nuclear Event Scale (INES) at level 1. In inspections carried out at TVO II during the annual maintenance outage, the number of cracks detected in control rod structural material was higher than usual. When cracks occur, part of boron carbide, the power regulating medium in control rods, may wash into the reactor water and control rod shutdown capability may be impaired. The event is rated on the INES at level 1. Other events in the second quarter of 1993 had no bearing on nuclear or radiation safety. (4 figs., 5 tabs.)

  8. ADHD in the Context of Finnish Basic Education

    Science.gov (United States)

    Honkasilta, J.; Sandberg, E.; Närhi, V.; Jahnukainen, M.

    2014-01-01

    Students with Attention Deficit/Hyperactivity Disorder (ADHD) are a growing group served under special education services in many western societies. This article describes the history and current state of the services, as well as the assessment procedure. Our conclusion is that the status of students with ADHD in Finnish basic education (Grades 1…

  9. Religious Conviction, Morality and Social Convention among Finnish Adolescents

    Science.gov (United States)

    Vainio, Annukka

    2011-01-01

    The assumptions of Kohlberg, Turiel and Shweder regarding the features of moral reasoning were compared empirically. The moral reasoning of Finnish Evangelical Lutheran, Conservative Laestadian and non-religious adolescents was studied using Kohlberg's Moral Judgment Interview and Turiel Rule Transgression Interview methods. Religiosity and choice…

  10. Personality Preferences and Career Expectations of Finnish Business Students.

    Science.gov (United States)

    Jarlstrom, Maria

    2000-01-01

    Predominant Myers Briggs Type Indicator (MBTI) scores for 533 Finnish business students were as follows: 67% extraverted, 53% intuitive, 67% thinking, and 33% feeling. For Schein's career anchors, 26% preferred Technical Competence, 17% Managerial Competence, and 14% Independence. Significant relationships between MBTI preferences and career…

  11. Job boredom and its correlates in 87 Finnish organizations

    NARCIS (Netherlands)

    Harju, Lotta; Hakanen, Jari J.; Schaufeli, Wilmar B.

    2014-01-01

    OBJECTIVE: To investigate the correlates of job boredom in 87 Finnish workplaces (N = 11,468) and to examine the associations between job boredom, health outcomes, and job attitudes. METHODS: We applied the Dutch Boredom Scale to measure job boredom. Hierarchical logistic regression analysis and

  12. A Finnish validation study of the SCL-90.

    Science.gov (United States)

    Holi, M M; Sammallahti, P R; Aalberg, V A

    1998-01-01

    The Symptom Check-List-90 (SCL-90) is a widely used psychiatric questionnaire which has not yet been validated in Finland. We investigated the utility of the translated version of the SCL-90 in the Finnish population, and set community norms for it. The internal consistency of the original subscales was checked and found to be good. Discriminant function analysis, based on the nine original subscales, showed that the power of the SCL-90 to discriminate between patients and the community is good. Factor analysis of the items of the questionnaire yielded a very strong unrotated first factor, suggesting that a general factor may be present. This together with the fact that high intercorrelations were found between the nine original subscales suggests that the instrument is not multidimensional. The SCL-90 may be useful in a research setting as an instrument for measuring the change in symptomatic distress, or as a screening instrument. The American community norms should be used with caution, as the Finnish community sample scored consistently higher on all subscales.

  13. The Finnish EPR dependent on a bridge

    International Nuclear Information System (INIS)

    Dupin, L.

    2010-01-01

    A new conflict has emerged between the main contractor Areva and its client TVO, the Finnish energy group. The qualification of a handling bridge has delayed the OL3 project of third EPR reactor at Olkiluoto, Finland. The disagreement concerns the testing procedure and may induce a two year delay in the completion of the project which is now planned for 2012 instead of 2010 initially. (J.S.)

  14. Identifying and Improving the image of Vietnam Tourism as a Tourism destination among Finnish tourist

    OpenAIRE

    Pham, Anh

    2012-01-01

    This writing attempts to identify the images of Vietnam as a tourism destination for Finnish tourists and suggests marketing solution for Vietnamese traveling company to improve the images of Vietnam by enhancing marketing activities in the Finnish market. Saigontourist Transportation Corporation (STC), Vietnam which is a commissioner of this thesis project, has provided updated information about the current situation of tourism in Vietnam as well as marketing activities of company durin...

  15. The Finnish power market: Are imports from Russia low-cost?

    International Nuclear Information System (INIS)

    Ochoa, Camila; Gore, Olga

    2015-01-01

    Electricity market integration of high- and low-price areas is expected to bring benefits to the consumers in a high-price area. However, these potential benefits are highly dependent on the market characteristics and the policy interventions. We use simulation to study the effects of different alternatives for the expansion and operation of the interconnector Finland–Russia on the Finnish market (a high-price area). Our results show that the current trading arrangement, where a single trader owns the transmission rights, and limits the trade during peak hours to avoid capacity charges in Russia, is beneficial for Finland at the current interconnection capacity. However, if the interconnector is expanded, the behaviour of the trader would create significant distortions in the Finnish market. We also analyse the pros and cons of maintaining a strategic reserve in Finland in combination with the different scenarios of interconnection expansion and trading arrangements. We conclude that in the absence of trust in imports, the need for a strategic reserve is undeniable. This will slightly reduce the economic benefits of integration for Finnish consumers, but it will significantly improve reliability. - Highlights: • We model the likely long-term dynamics of the interconnection Finland–Russia. • Different cross-border arrangements and capacity adequacy policies are considered. • Discriminatory access to the interconnector undermines the benefits of integration. • Market coupling reduces supply costs but creates reliability concerns. • Keeping a strategic reserve reduces the benefits of market coupling

  16. Peptides in fermented Finnish milk products

    Directory of Open Access Journals (Sweden)

    Minna Kahala

    1993-09-01

    Full Text Available This study was conducted to investigate the rate of proteolysis and peptide profiles of different Finnish fermented milk products. The highest rate of proteolysis was observed in Biokefir, while the greatest change in the rate of proteolysis was observed in Gefilus®. Differences in starters and manufacturing processes reflected on the peptide profiles of the products. Most of the identified peptides originated from either the N- or C-terminal region of β-casein or from the N-terminal region of αs1-casein.

  17. Attitudes toward guidelines in Finnish primary care nursing: a questionnaire survey

    DEFF Research Database (Denmark)

    Seija, Alanen; Kaila, Minna; Välimäki, Marita

    2009-01-01

    to be shaped by perceptions of others, which makes the role of organizational implementation interventions interesting. AIMS: This article describes primary care nurses' attitudes toward guidelines among Finnish primary care nurses and the associations between attitudes, implementation interventions...... more positively and that guidelines were more easily available. Further, nurses who were familiar or very familiar with the guidelines had more positive attitudes toward them. Attitudes were also associated with self-reported guideline use. CONCLUSIONS: The evidence-based guidelines were accepted...... as a reliable source of advice in patient care in Finnish primary care. It seems that implementation interventions improve attitudes toward guidelines and enhance guideline use. These interventions might also be important from another point of view; they presumably improve familiarity with guidelines, which...

  18. Primers As Socializing Agents in American and Finnish Schools.

    Science.gov (United States)

    Hyona, Jukka; And Others

    1995-01-01

    Content analysis of 12 Finnish and 18 American primers for grades 3 through 6 published primarily during the 1980s examined story type, plot setting, protagonist's characteristics, dramatic tasks, portrayals of family structure and parental responsibility, and extrafamilial peer and adult relationships. Results suggest that a nation's cultural…

  19. On Moral Education in the Finnish Comprehensive School Curriculum.

    Science.gov (United States)

    Hakkarainen, Pentti

    1978-01-01

    Basic values of moral education in Finnish schools come from the Universal Declaration of Human Rights. Moral tenets are taught in religion and civics. The textbooks deal with moral questions mainly on the individual level and provide limited opportunities for practice necessary for the internalization of values. (Author/SJL)

  20. Jackson-Weiss syndrome: Clinical and radiological findings in a large kindred and exclusion of the gene from 7p21 and 5qter

    Energy Technology Data Exchange (ETDEWEB)

    Ades, L.C.; Haan, E.A.; Mulley, J.C.; Senga, I.P.; Morris, L.L.; David, D.J. [Women`s and Children`s Hospital, North Adelaide (Australia)

    1994-06-01

    We describe the clinical and radiological manifestations of the Jackson-Weiss syndrome (JWS) in a large South Australian kindred. Radiological abnormalities not previously described in the hands include coned epiphyses, distal and middle phalangeal hypoplasia, and carpal bone malsegmentation. New radiological findings in the feet include coned epiphyses, hallux valgus, phalangeal, tarso-navicular and calcaneo-navicular fusions, and uniform absence of metatarsal fusions. Absence of linkage to eight markers along the short arm of chromosome 7 excluded allelian between JWS and Saethre-Chotzen syndrome at 7p21. No linkage was detected to D5S211, excluding allelism to another recently described cephalosyndactyly syndrome mapping to 5qter. 35 refs., 5 figs., 4 tabs.

  1. Intercomparison of Finnish and Russian whole-body counters used for the determination of 137Cs body burden in reindeer-herding populations

    International Nuclear Information System (INIS)

    Rahola, T.; Tillander, M.

    1995-01-01

    Intercalibration is a very important quality control in whole-body counting, as the human body is a very difficult ''sample'' to calibrate for. In 1994 the Finnish Centre for Radiation and Nuclear Safety (STUK), the Laboratory of Radiochemistry of the University of Helsinki and the Institute of Radiation Hygiene (IRH) of St. Petersburg agreed to undertake the first Finnish-Russian intercalibration project for whole-body counters. The monitoring of body burdens of indigenous inhabitants in the far north of Russia, from the Kola Peninsula to Chuhodka, has been the responsibility of the ISH since 1960; the above-.mentioned Finnish institutes have monitored reindeer breeders in Finnish Lapland since 1961. The intercalibration was done in the field by measuring the same persons with both systems in Finnish Lapland and in the Kola Peninsula. Mean body burdens in the reindeer-herding population in the areas of current interest are presented in the present paper. 7 refs., 3 figs., 1 tab

  2. Exports of Finnish wind power technology gaining momentum

    International Nuclear Information System (INIS)

    2005-01-01

    In the 1990s, Finnish companies in the wind power sector focused on supplying advanced components and materials. This capability has now extended to cover entire turbines and wind farms. Winwind Oy, based in northern Finland, has developed a new type of solution for the export market, combining the advantages of modem direct drives with those of traditional high-speed gear systems

  3. Recent adverse trends in semen quality and testis cancer incidence among Finnish men

    DEFF Research Database (Denmark)

    Jorgensen, N.; Vierula, M.; Jacobsen, R.

    2011-01-01

    Impaired semen quality and testicular cancer may be linked through a testicular dysgenesis syndrome of foetal origin. The incidence of testis cancer has been shown to increase among Finnish men, whereas there is no recent publication describing temporal trends in semen quality. Therefore, we...... carried out a prospective semen quality study and a registry study of testis cancer incidence among Finnish men to explore recent trends. A total of 858 men were investigated in the semen quality study during 1998-2006. Median sperm concentrations were 67 (95% CI 57-80) million/mL, 60 (51-71) and 48 (39...

  4. Founder representation and effective population size in old versus young breeds-genetic diversity of Finnish and Nordic Spitz.

    Science.gov (United States)

    Kumpulainen, M; Anderson, H; Svevar, T; Kangasvuo, I; Donner, J; Pohjoismäki, J

    2017-10-01

    Finnish Spitz is 130-year-old breed and has been highly popular in Finland throughout its history. Nordic Spitz is very similar to Finnish Spitz by origin and use, but is a relatively recent breed with much smaller population size. To see how breed age and breeding history have influenced the current population, we performed comprehensive population genetic analysis using pedigree data of 28,119 Finnish and 9,009 Nordic Spitzes combined with genomewide single nucleotide polymorphism (SNP) data from 135 Finnish and 110 Nordic Spitzes. We found that the Finnish Spitz has undergone repeated male bottlenecks resulting in dramatic loss of genetic diversity, reflected by 20 effective founders (f a ) and mean heterozygosity (Hz) of 0.313. The realized effective population size in the breed based on pedigree analysis (N¯ec) is 168, whereas the genetic effective population size (N eg ) computed the decay of linkage disequilibrium (r 2 ) is only 57 individuals. Nordic Spitz, although once been near extinction, has not been exposed to similar repeated bottlenecks than Finnish Spitz and had f a of 27 individuals. However, due to the smaller total population size, the breed has also smaller effective population size than Finnish Spitz (N¯ec = 98 and N eg  = 49). Interestingly, the r 2 data show that the effective population size has contracted dramatically since the establishment of the breed, emphasizing the role of breed standards as constrains for the breeding population. Despite the small population size, Nordic Spitz still maintains SNP heterozygosity levels similar to mixed breed dogs (mean Hz = 0.409). Our study demonstrates that although pedigree analyses cannot provide estimates of the present diversity within a breed, the effective population sizes inferred from them correlate with the genotyping results. The genetic relationships of the northern Spitz breeds and the benefits of the open breed registry are discussed. © 2017 Blackwell Verlag GmbH.

  5. "Virtuoso Ideal Daddy": Finnish Children's Perceptions of Good Fatherhood

    Science.gov (United States)

    Hietanen, Riika; Määttä, Kaarina; Uusiautti, Satu

    2013-01-01

    Changes in family structures, such as the increase in the number of cohabiting couples, divorces, and blended families pose new challenges for fatherhood and research on fatherhood has been mainly adult-centred. This research studied how Finnish children perceive good fatherhood and what expectations they set for fathers. The following research…

  6. SAFIR2014. The Finnish Research Programme on Nuclear Power Plant Safety 2011-2014. Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Simola, K. [ed.

    2013-02-15

    The Finnish Nuclear Power Plant Safety Research Programme 2011-2014, SAFIR2014, is a 4-year publicly funded national technical and scientific research programme on the safety of nuclear power plants. The programme is funded by the State Nuclear Waste Management Fund (VYR), as well as other key organisations operating in the area of nuclear energy. The programme provides the necessary conditions for retaining knowledge needed for ensuring the continuance of safe use of nuclear power, for developing new know-how and for participation in international co-operation. The SAFIR2014 Steering Group, responsible of the strategic alignements of the programme, consists of representatives of the Finnish Nuclear Safety Authority (STUK), Ministry of Employment and the Economy (MEE), Technical Research Centre of Finland (VTT), Teollisuuden Voima Oyj (TVO), Fortum Power and Heat Oy (Fortum), Fennovoima Oy, Lappeenranta University of Technology (LUT), Aalto University (Aalto), Finnish Funding Agency for Technology and Innovation (Tekes), Finnish Institute of Occupational Health (TTL) and the Swedish Radiation Safety Authority (SSM). The research programme is divided into nine areas: Man, organisation and society, Automation and control room, Fuel research and reactor analysis, Thermal hydraulics, Severe accidents, Structural safety of reactor circuits, Construction safety, Probabilistic risk analysis (PRA), and Development of research infrastructure. A reference group is assigned to each of these areas to respond for the strategic planning and to supervise the projects in its respective field. Research projects are selected annually based on a public call for proposals. Most of the projects are planned for the entire duration of the programme, but there can also be shorter one- or two-year projects. The annual volume of the SAFIR2014 programme in 2011-2012 has been 9,5-9,9 M euro. Main funding organisations were the State Nuclear Waste Management Fund (VYR) with over 5 M euro and

  7. SAFIR2014. The Finnish Research Programme on Nuclear Power Plant Safety 2011-2014. Interim Report

    International Nuclear Information System (INIS)

    Simola, K.

    2013-02-01

    The Finnish Nuclear Power Plant Safety Research Programme 2011-2014, SAFIR2014, is a 4-year publicly funded national technical and scientific research programme on the safety of nuclear power plants. The programme is funded by the State Nuclear Waste Management Fund (VYR), as well as other key organisations operating in the area of nuclear energy. The programme provides the necessary conditions for retaining knowledge needed for ensuring the continuance of safe use of nuclear power, for developing new know-how and for participation in international co-operation. The SAFIR2014 Steering Group, responsible of the strategic alignements of the programme, consists of representatives of the Finnish Nuclear Safety Authority (STUK), Ministry of Employment and the Economy (MEE), Technical Research Centre of Finland (VTT), Teollisuuden Voima Oyj (TVO), Fortum Power and Heat Oy (Fortum), Fennovoima Oy, Lappeenranta University of Technology (LUT), Aalto University (Aalto), Finnish Funding Agency for Technology and Innovation (Tekes), Finnish Institute of Occupational Health (TTL) and the Swedish Radiation Safety Authority (SSM). The research programme is divided into nine areas: Man, organisation and society, Automation and control room, Fuel research and reactor analysis, Thermal hydraulics, Severe accidents, Structural safety of reactor circuits, Construction safety, Probabilistic risk analysis (PRA), and Development of research infrastructure. A reference group is assigned to each of these areas to respond for the strategic planning and to supervise the projects in its respective field. Research projects are selected annually based on a public call for proposals. Most of the projects are planned for the entire duration of the programme, but there can also be shorter one- or two-year projects. The annual volume of the SAFIR2014 programme in 2011-2012 has been 9,5-9,9 M euro. Main funding organisations were the State Nuclear Waste Management Fund (VYR) with over 5 M euro and

  8. Finnish Play Becomes Chinese Local Opera

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    IN the fall of 1992 an unusualpremiere took place in Xi′an:Totisesti totisesti,adapted from aFinnish stage play,was performed asan opera in Chinese by the HuaOpera Troupe,a part of the ShaanxiOpera Research Institute.Ms.InkeriKilpinen,the playwright,and Ms.Leena Laulajainen,vice-chairman ofFinland Writers′Association,cameto see the performance.Hua opera,also known as“Wanwan Opera,”is one of the localforms of opera in Shaanxi Province.It was originally performed in theform of shadow play,and was for-

  9. Are Cross-National Differences in IQ Profiles Stable? A Comparison of Finnish and U.S. WAIS Norms

    Science.gov (United States)

    Roivainen, Eka

    2013-01-01

    To study the concept of national IQ profile, we compared U.S. and Finnish WAIS, WAIS-R, and WAIS III nonverbal and working memory subtest norms. The U.S. standardization samples had consistently higher scores on the Coding and Digit span subtests, while the Finnish samples had higher scores on the Block design subtest. No stable cross-national…

  10. The history of Finnish nuclear non-proliferation policy during the cold war. What did the Finns know about nuclear weapons

    International Nuclear Information System (INIS)

    Ahosniemi, A.

    2004-03-01

    This article is a summary of the Finnish historical survey during the Cold War. In the article, I try to show how the Finnish Nuclear Non-Proliferation Policy during the Cold War is linked to the broader context of the Finnish foreign and security policy. In the research report I have focused on several questions. One of the most important is the following: What did the Finns know about nuclear weapons during the Cold War? And in this context scientific knowledge is meant by knowing something about nuclear weapons. Basically, the Finnish national based survey of nuclear non-proliferation policy attempted to investigate issues like the kind of research concerning Nuclear Technology in general, Nuclear weapons, and Nuclear weapon policies of super powers in Finland during the Cold War era. (author)

  11. Assessment of reliability and maintenance of motor operated valves at Finnish NPPS

    International Nuclear Information System (INIS)

    Laakso, K.; Haenninen, S.; Simola, K.

    1994-01-01

    This paper summarizes two studies on motor operated valve (MOV) failure and maintenance experiences in Finnish nuclear power plants. In the first study, described in section 2 of this paper, the failure reports of MOVs at Finnish BWR units from a nine years' time period were analyzed in a systematic way. The dominant failure mechanisms were identified and time-dependencies in failure occurrence were studied. This study initiated an experience based reliability centered maintenance (RCM) analysis of motor operated valve drives, which is summarized in chapter 3 of this paper. The RCM analysis resulted in the identification and proposal of the most suitable and effective maintenance tasks for consideration. 9 refs, 3 figs, 1 tab

  12. Procurement of timber for the Finnish forest industries

    International Nuclear Information System (INIS)

    Hakkila, P.

    1995-01-01

    The procurement of timber to the forest industries in the Nordic countries is based on the log-length or shortwood system, and employs load-carrying forwarders and chainsaw of single-grip harvesters. This technology is characterized by high productivity, safety, suitability for small-sized trees, high recovery of timber, and environmental friendliness. About one fourth of the industrial timber in the whole world is harvested using the log-length system. The challenge of ecological sustainability, multiple use of forests, adoption of thinnings as a tool of management, trend toward improved utilization of forest biomass, and shift from natural forests to plantations all increase the global interest in the log-length system. The paper presents a review of the Finnish forest sector, the technology of timber harvesting and transport, productivity of logging work, and costs of timber at the mill. The highly mechanized logging systems of the forest industries and the lighter technology of self-employed forest owners are discussed separately. Furthermore, the use of residual biomass as a source of clean and renewable energy, the Finnish logging machine industry, and forest operations research in Finland are also reviewed. (46 refs., 35 figs., 8 tabs.)

  13. The mRNA level of MLH1 in peripheral blood is a biomarker for the diagnosis of hereditary nonpolyposis colorectal cancer.

    Science.gov (United States)

    Yu, Hong; Li, Hui; Cui, Yongan; Xiao, Wei; Dai, Guihong; Huang, Junxing; Wang, Chaofu

    2016-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by functional defects in mismatch repair (MMR) genes, including mutL homolog 1 (MLH1) and mutS homolog 2 (MSH2). This study aimed to assess whether the mRNA expression of MLH1 in peripheral blood could be used as a biomarkers for the diagnosis of HNPCC. The mRNA level of MLH1 was determined in 19 HNPCC families (46 members) using real-time quantitative polymerase chain reaction (qPCR). The mRNA levels of MLH1 in HNPCC were significantly lower than controls (P MLH1 for the diagnosis of HNPCC with the area under curve of 0.858. At an optimal cut-off value (0.511), the mRNA level of MLH1 had a sensitivity of 81.3% and a specificity of 86.7% for distinguishing HNPCC from controls. In conclusion, the mRNA expression of MLH1 in peripheral blood may serve as a biomarker for the diagnosis of HNPCC.

  14. Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

    Science.gov (United States)

    Umar, Asad; Boland, C. Richard; Terdiman, Jonathan P.; Syngal, Sapna; de la Chapelle, Albert; Rüschoff, Josef; Fishel, Richard; Lindor, Noralane M.; Burgart, Lawrence J.; Hamelin, Richard; Hamilton, Stanley R.; Hiatt, Robert A.; Jass, Jeremy; Lindblom, Annika; Lynch, Henry T.; Peltomaki, Païvi; Ramsey, Scott D.; Rodriguez-Bigas, Miguel A.; Vasen, Hans F. A.; Hawk, Ernest T.; Barrett, J. Carl; Freedman, Andrew N.; Srivastava, Sudhir

    2010-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a common autosomal dominant syndrome characterized by early age at onset, neoplastic lesions, and microsatellite instability (MSI). Because cancers with MSI account for approximately 15% of all colorectal cancers and because of the need for a better understanding of the clinical and histologic manifestations of HNPCC, the National Cancer Institute hosted an international workshop on HNPCC in 1996, which led to the development of the Bethesda Guidelines for the identification of individuals with HNPCC who should be tested for MSI. To consider revision and improvement of the Bethesda Guidelines, another HNPCC workshop was held at the National Cancer Institute in Bethesda, MD, in 2002. In this commentary, we summarize the Workshop presentations on HNPCC and MSI testing; present the issues relating to the performance, sensitivity, and specificity of the Bethesda Guidelines; outline the revised Bethesda Guidelines for identifying individuals at risk for HNPCC; and recommend criteria for MSI testing. PMID:14970275

  15. Airborne fallout mapping of {sup 137}Cs Finnish defence forces team

    Energy Technology Data Exchange (ETDEWEB)

    Kettunen, M.; Heininen, T. [Finnish Defence Forces Research Centre, Lakiala (Finland); Pulakka, M. [Finnish Air Force Depot, Tampere (Finland)

    1997-12-31

    The main task of the team was to create a fallout map of {sup 137}Cs in a specified area in Padasjoki Auttoinen village. The team used an MI-8 helicopter of the Finnish Air Force. The team had an HPGe system (relative efficiency 70%) to measure nuclide specific ground contamination level. For navigation the team took advantage of the DGPS service provided by Finnish Broadcasting company utilizing the RDS-channel to get position accuracy within 2 meters. The correction signal is reachable nationwide on the FM transmitter network. The system produced a distribution map for {sup 40}K and fallout maps for {sup 134,137}Cs using a Micro Station Program with TerraModeler application. The maximum measured {sup 137}Cs ground contamination exceeded 130-140 kBqm{sup -2}. (au).

  16. Airborne fallout mapping of {sup 137}Cs Finnish defence forces team

    Energy Technology Data Exchange (ETDEWEB)

    Kettunen, M; Heininen, T [Finnish Defence Forces Research Centre, Lakiala (Finland); Pulakka, M [Finnish Air Force Depot, Tampere (Finland)

    1998-12-31

    The main task of the team was to create a fallout map of {sup 137}Cs in a specified area in Padasjoki Auttoinen village. The team used an MI-8 helicopter of the Finnish Air Force. The team had an HPGe system (relative efficiency 70%) to measure nuclide specific ground contamination level. For navigation the team took advantage of the DGPS service provided by Finnish Broadcasting company utilizing the RDS-channel to get position accuracy within 2 meters. The correction signal is reachable nationwide on the FM transmitter network. The system produced a distribution map for {sup 40}K and fallout maps for {sup 134,137}Cs using a Micro Station Program with TerraModeler application. The maximum measured {sup 137}Cs ground contamination exceeded 130-140 kBqm{sup -2}. (au).

  17. Operation of Finnish nuclear power plants. Quarterly report, 3rd quarter 1996

    International Nuclear Information System (INIS)

    Sillanpaeae, T.

    1997-02-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which the Finnish Centre for Radiation and Nuclear Safety (STUK) considers safety significant. Safety improvements at the plants are also described. The Report also includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants' production and load factors. In the third quarter of 1996, the Finnish nuclear power plant units were in power operation except for the annual maintenance outages of Loviisa plant units and a shutdown at Olkiluoto 1 to identify and repair malfunctions of a high pressure turbine control valve. The load factor average of all plant units was 77.2%. Events in the third quarter of 1996 were classified level 0 on the International Nuclear Event Scale. Occupational doses and radioactive releases off-site were below authorised limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. The names of Teollisuuden Voima Oy's plant units have changed. Olkiluoto 1 and Olkiluoto 2 now replace the names TVO I and TVO II previously used in quarterly reports. (orig.)

  18. Awareness and use of the Heart Symbol by Finnish consumers.

    Science.gov (United States)

    Lahti-Koski, Marjaana; Helakorpi, Satu; Olli, Mari; Vartiainen, Erkki; Puska, Pekka

    2012-03-01

    To study the awareness of the Heart Symbol in different age and educational groups, and changes in the awareness over a 9-year period. In addition, the reported use of products with the symbol was examined. A series of annual cross-sectional postal surveys on Health Behaviour and Health among the Finnish Adult Population. A random sample (n 5000 per annum) from the Finnish population aged 15-64 years, drawn from the National Population Register, received a questionnaire. Men and women (n 29 378) participating in the surveys in 2000-2009. At the early 2000s, 48 % of men and 73 % of women reported to be familiar with the symbol. The corresponding rates were 66 % for men and 91 % for women in 2009. The reported use of products with the symbol increased from 29 % to 52 % in men and from 40 % to 72 % in women. In men, the awareness did not vary by age, whereas older women (45-64 years) were less likely to be aware of the symbol compared with younger women (25-34 years). Men and women with the highest education were best aware of the symbol and more likely to use the products in the early 2000s. The educational differences diminished or disappeared during the study period. The majority of Finnish adults are familiar with the Heart Symbol, and the reported use of such products increased in all age and educational groups, especially among the less educated. The symbol may work as an effective measure to diminish nutrition-related health inequalities.

  19. Ground beetle (Coleoptera, Carabidae diversity in Finnish arable land

    Directory of Open Access Journals (Sweden)

    J.K. HELENIUS

    2008-12-01

    Full Text Available Carabid data compiled from six independent studies, consisting of 97 799 individuals trapped by pitfalls from Finnish agricultural fields and identified to 111 species were analyzed. Shannon-Wiener H' diversity index was typically around 2.5 and expected species number rarefied to 600 trapped individuals was typically around 30 species. The five most abundant species accounted for 42% of the total catch, and the thirty most abundant species made up 98% of the total catch. Percentage similarities among the assemblages by PS-index were from 16% to 48%. In comparison to published data about carabid diversity in boreal forests, which form the dominating habitat matrix in which Finnish farmland is embedded as relatively small patches, arable fields harbor more species rich assemblages, with more even rank-abundance distributions but variable species composition. Importance of landscape (regional level, instead of spatial level of crop fields, in understanding carabid diversity in farmland is discussed. Inclusion of carabids into monitoring schemes of agro-biodiversity at landscape level is suggested.

  20. Ozone and UV research at Finnish Meteorological Inst.: review of selected results

    Energy Technology Data Exchange (ETDEWEB)

    Taalas, P; Koskela, T; Damski, J; Supperi, A [Finnish Meteorological Inst., Helsinki (Finland). Section of Ozone and UV Research; Kyroe, E [Finnish Meteorologican Inst., Sodankylae (Finland). Sodankylae Observatory; Ginzburg, M [Servicio Meteorologico Nacional, Buenos Aires (Argentina); Dijkhuis, J L [Finnish Meteorological Inst., Helsinki (Finland). EUMETSAT

    1996-12-31

    Ozone and UV radiation research have become an important part of atmospheric research at Finnish Meteorological Institute after the discovery of chlorine based ozone loss in the Antarctic stratosphere

  1. Ozone and UV research at Finnish Meteorological Inst.: review of selected results

    Energy Technology Data Exchange (ETDEWEB)

    Taalas, P.; Koskela, T.; Damski, J.; Supperi, A. [Finnish Meteorological Inst., Helsinki (Finland). Section of Ozone and UV Research; Kyroe, E. [Finnish Meteorologican Inst., Sodankylae (Finland). Sodankylae Observatory; Ginzburg, M. [Servicio Meteorologico Nacional, Buenos Aires (Argentina); Dijkhuis, J.L. [Finnish Meteorological Inst., Helsinki (Finland). EUMETSAT

    1995-12-31

    Ozone and UV radiation research have become an important part of atmospheric research at Finnish Meteorological Institute after the discovery of chlorine based ozone loss in the Antarctic stratosphere

  2. Sense of mastery differences between working-age Swedish- and Finnish-speaking Finns: a population-based study.

    Science.gov (United States)

    Reini, Kaarina; Nyqvist, Fredrica

    2017-06-01

    To examine the probability of a high sense of mastery in a population-representative sample of working-age people and to study the differences in mastery between Finnish-speaking and Swedish-speaking Finns in particular. The data originates from the Western Finland Mental Health Surveys (2008-2014). Associations between sense of mastery and language groups were analyzed with logistic regressions. Swedish-speaking Finns have a higher sense of mastery and the association is mediated by social support. Moreover, a difference in a high sense of mastery is found between Swedish- and Finnish-speaking married women that are outside the labor market. Our findings imply that Finnish-speaking women that are outside the labor market, e.g. on maternity leave or taking care of the household, should be recognized in health and social care services as a group that can benefit from additional support.

  3. Finnish support programme to IAEA safeguards. Annual report 1994; Suomen tukiohjelma IAEA:n safeguards-valvonnalle. Vuoden 1994 toimintakertomus

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, M [ed.

    1995-05-01

    Implementation of the Finnish Support Programme to IAEA Safeguards (FINSP) during the calender year in question is summarized. FINSP is carried out trough separate tasks concentrating on verification of nuclear material, training and expert services to the IAEA. In addition to the Finnish summary, the report includes detailed description of each task in English.

  4. From Ridiculed Deviants towards Normal Citizens. The Representation of Homosexuals in the Finnish Media 1990 - 2010

    OpenAIRE

    Ylppö, Myrsky

    2016-01-01

    This thesis explores how the Finnish media’s representations of homosexual men and women changed between 1990 and 2010, from negative public portrayals towards more positive ones. The thesis also examines if these changes reflect attitudes and opinions of the Finnish society and population overall during this time period. The primary sources consist of newspaper articles from the newspaper Helsingin Sanomat, along with material from other newspapers, tabloids, and supporting research material...

  5. Teaching Islamic Education in Finnish Schools: A Field of Negotiations

    Science.gov (United States)

    Rissanen, Inkeri

    2012-01-01

    The challenges of contemporary multicultural societies have resulted in changing aims for religious education and the necessity to adjust teacher education accordingly. The processes of negotiation related to the coexistence of different religious and cultural groups are intertwined in the Finnish curriculum for religious education. This case…

  6. Indoor climate and the performance of ventilation in Finnish residences

    International Nuclear Information System (INIS)

    Ruotsalainen, R.; Roennberg, R.; Saeteri, J.; Majanen, A.; Seppaenen, O.; Jaakkola, J.J.K.

    1992-01-01

    The purpose of the study was to gather information about the actual ventilation and indoor air quality and to evaluate the differences between houses and apartments with different ventilation systems. A sample of 242 dwellings in the Helsinki metropolitan area was studied over periods of two weeks during the 1988-1989 heating season. The mean air-exchange rates had a high variation (average 0.52 l/h, range 0.07-1.55 l/h). The ASHRAE minimum value of 0.35 l/h was not achieved in 28% of the dwellings. The air-exchange rates were significantly lower in the houses than in the apartments (averages 0.45/0.64 l/h, p 3 (range 5-866 Bq/m 3 ); the Finnish target value of 200 Bq/m 3 was exceeded in 17% of the houses but in none of the apartments. The measurements indicate that the indoor air quality in Finnish dwellings is not always satisfactory with reference to human health and comfort. (au)

  7. Psychometric properties of the Finnish version of the Women's Health Questionnaire.

    Science.gov (United States)

    Katainen, Riina E; Engblom, Janne R; Vahlberg, Tero J; Polo-Kantola, Päivi

    2017-08-01

    The Women's Health Questionnaire (WHQ) is a validated and commonly used instrument for measuring climacteric-related symptoms. A revised version was previously developed. However, validation in a Finnish population is lacking. As it is important to use qualified instruments, we performed a validation study of the WHQ in a Finnish population. In all, 3,421 women, aged 41 to 54 years, formed the study population. In the original 36-item WHQ, the items were rated on a 1 to 4 scale and on a binary scale (0-1). The scaling of the revised 23-item WHQ was 0 to 100. We evaluated the psychometric properties (internal consistency, correlations between the symptom domains, factor structure, and sampling adequacy) in all three versions. For the 1 to 4 scale and on the revised version of the WHQ, the internal consistency was acceptable (the Cronbach's α coefficients >0.70) for most of the domains. On the binary scale, the majority of the coefficient values were below the acceptable level. The original symptom domains, especially those on the revised version, were recognizable from the factors in the exploratory factor analysis, but there were some limitations. The Kaiser-Meyer-Olkin values were high. The WHQ is a valid instrument for measuring climacteric-related symptoms in Finnish middle-aged women. The psychometric properties of the revised 23-item WHQ were as good or even better than those of the original 36-item WHQ. Thus, we encourage use of the revised version.

  8. Transnational sense of place: cinematic scenes of Finnish war child memories

    Directory of Open Access Journals (Sweden)

    Anna-Kaisa Kuusisto-Arponen

    2011-05-01

    Full Text Available In this article I discuss the role of popular geopolitics and people's performative repertoires in voicing the social silence. I have selected for close-reading some of the episodes of the film Mother of Mine, which tells the story of a Finnish war child. In my analysis I ask what the transnational memory sites of forced displacement are, how they are depicted, and in general what kind of socio-spatial identity struggles they are involved in. Moreover, in this article I argue that the many forms through which silence becomes expressive need to be studied on the scale of the body and daily performative practices. Thus, I conclude that through several daily practices the Finnish war children unconsciously developed transnational agencies in order to survive and re-create the existential social and spatial ties of belonging.

  9. Finnish perspectives of wireless in healthcare.

    Science.gov (United States)

    Alasaarela, Esko

    2009-01-01

    Wireless solutions are a good choice for healthcare development in Finland. A survey of 135 experts in Finland show that (1) the competences needed for developing wireless solutions exist (2) the Finnish healthcare system is integrated enough and (3) the technology industry in this area is too weak for global marketing. The following recommendations can be concluded: (1) Cooperate internationally (2) Develop integrated solutions and health managing concepts for the important health problems (such as diabetes), (3) Harness the healthcare system to act as a test bed for new solutions and (4) Help companies to grow and take global roles.

  10. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1991-02-01

    During the third quarter of 1990 the Finnish nuclear power plant units Loviisa 1 and 2 and TVO I and II were in commercial operation for most of the time. The annual maintenance outages of the Loviisa plant units were held during the report period. All events during this quarter are classified as Level hero (Below Scale) on the International Nuclear Event Scale. Occupational radiation doses and external releases of radioactivity were below authorised limits. Only small amounts of radioactive substances originating in nuclear power plants were detected in samples taken in the vicinity of nuclear power plants

  11. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1992-09-01

    The Finnish nuclear power plant units Loviisa 1 and 2 as well as TVO I and II were in operation for almost all the time in the first quarter of 1992. The load factor average was 99.8%. All events which are classified on the International Nuclear Event Scale were level 0/below scale on the Scale. Occupational radiation doses and releases of radioactive material off-site remained well below authorised limits. Only quantities of radioactive material insignificant to radiation exposure, originating from the nuclear power plants, were detected in samples collected in the vicinity of the nuclear power plants

  12. Phenotypic and genotypic characterization of Flavobacterium psychrophilum from Finnish fish farms

    DEFF Research Database (Denmark)

    Madetoja, J.; Hanninen, M.L.; Hirvela-Koski, V.

    2001-01-01

    Finnish isolates (n = 37) of Flavobacterium psychrophilum isolated from farmed salmonids were studied using phenotypic and genotypic characteristics. The characteristics of isolates were compared with the characteristics of Swedish and Estonian F. psychrophilum isolates and the type strain, F...

  13. Effective Mathematics Teaching in Finnish and Swedish Teacher Education Discourses

    Science.gov (United States)

    Hemmi, Kirsti; Ryve, Andreas

    2015-01-01

    This article explores effective mathematics teaching as constructed in Finnish and Swedish teacher educators' discourses. Based on interview data from teacher educators as well as data from feedback discussions between teacher educators and prospective teachers in Sweden and Finland, the analysis shows that several aspects of the recent…

  14. Computer-Based Molecular Modelling: Finnish School Teachers' Experiences and Views

    Science.gov (United States)

    Aksela, Maija; Lundell, Jan

    2008-01-01

    Modern computer-based molecular modelling opens up new possibilities for chemistry teaching at different levels. This article presents a case study seeking insight into Finnish school teachers' use of computer-based molecular modelling in teaching chemistry, into the different working and teaching methods used, and their opinions about necessary…

  15. Finnish Government contribution in Haiphong Water Supply, Drainage, Sewerage and Sanitation Management Programs in Hai Phong city, Vietnam : A Case Study

    OpenAIRE

    Nguyen Hoang, Duy

    2015-01-01

    The objective of the thesis is to bring out a general point of view in the contribution of the Finnish aid of Finnish Government, targeted in the development of urban area as well as water supply and sanitation of Hai Phong city, the most Northern port city of Vietnam, which holds an important role in the economy system of Vietnam. Moreover, Hai Phong is one of three targeted cities that get Foreign Direct Investment as well as support from Finnish government for the development of local wate...

  16. [Implantation of a hospital registry of hereditary nonpolyposis colorectal cancer].

    Science.gov (United States)

    Reyes, J; Ginard, D; Barranco, L; Escarda, A; Vanrell, M; Mariño, Z; Garau, I; Llompart, A; Gayà, J; Obrador, A

    2006-10-01

    Identification of patients with hereditary nonpolyposis colorectal cancer (HNPCC) can allow colorectal cancer (CRC) prevention through colonoscopy and polypectomies. The purpose of this study was to report the clinical characteristics of HNPCC families in our registry. HNPCC was identified using the Amsterdam criteria. Familial clustering of CRC and extracolonic cancers were investigated in families. Individuals at risk were offered annual colonoscopy, starting from the age of 25 years. Twelve HNPCC families were identified. There were 46 cases of CRC in 38 patients. The mean age at diagnosis of CRC was 45.4 +/- 12.7 years (range 25-73 years). In patients with documented disease, right-sided tumors predominated. Eleven patients with extracolonic cancer were identified (six tumors located in the endometrium). Of 43 at-risk individuals, 29 accepted surveillance. Our data confirm the importance of the family history in identifying HNPCC. This study confirms previously described characteristics in HNPCC, namely, early age at onset of CRC, right-sided predominance, multiple synchronous and metachronous neoplasms, and increased extracolonic cancers. This is the first study of clinical data in a Spanish HNPCC registry.

  17. Economic Co-operation Across the Finnish-Russian Border - Factors of Sluggish Development and Success of Enterprises

    OpenAIRE

    Rautio, V.; Tykkylaeinen, M.

    2000-01-01

    The post-Cold War era in Europe in the 1990s has caused people to recognize the complexity of economic development and economic co-operation. The opening of borders has not always meant an increase cross-border economic activities in general. On the contrary, the adverse socio-economic development of many border areas has been unanticipated. The Finnish-Russian border is one example of this dissonance. This paper analyses the operation of Finnish companies in economic activities in Russ...

  18. Late-life functional capacity and health among Finnish war veterans:Veteran Project 1992 and 2004 surveys

    OpenAIRE

    Leskinen, R. (Riitta)

    2015-01-01

    Abstract Becoming involved in war is an experience that has the potential to shape later-life health. The aim of the present study was to explore Finnish Second World War veterans’ health status and the determinants of self-rated health (SRH) and functional capacity, especially the ability to walk, and to identify risk factors and their combinations that predict late-life mortality among veterans. The study population comprised Finnish Second World War veterans who participated in the ...

  19. Important themes in research on and education of young children in day care centres: Finnish viewpoints

    Directory of Open Access Journals (Sweden)

    Maritta Hännikäinen

    2013-10-01

    Full Text Available The aim of this article is to outline important themes, according to Finnish early childhood education researchers, that need to be addressed in researching and educating children under three years of age in Finland. To achieve this aim, the article divides into two parts. First, we present and discuss the results of a small-scale survey, conducted in Finland, on the views of key informants in the early childhood education units of Finnish universities. Second, the views presented in the survey are used as a starting point to introduce two ongoing qualitative case studies on the everyday life of toddlers in Finnish day care centres. In line with the survey findings, these case studies emphasize in particular the importance of the relational, social nature of children, the educational community, and the sensitivity of the adult for children’s wellbeing in day care groups.

  20. Conversion rate optimization in Finnish online businesses

    OpenAIRE

    Ratia, Miramaria; Ruoho, Vilma

    2016-01-01

    Conversion rate optimization (CRO) is an unfamiliar term to many online business owners even though it has become almost as important as search engine optimization is in e-commerce today. It is a method that is used to turn passive visitors into active users in order to improve a website’s performance. The main objective of this thesis was to find out what kinds of conversion rate optimization methods do Finnish small and medium-sized online businesses use. The thesis also studies what ar...

  1. Project Management in the Finnish Music Industry

    OpenAIRE

    Hypén, Joel

    2009-01-01

    The term project is a widely used phrase in today’s working life. This thesis explains what project management theory is, how it has evolved through history and how it is applied in managing modern business projects in the contexts of the Finnish music business sector. The literature review contains a description of the key phases a project is typically organised in as well as the terms and tools used to plan and run a successful project. Through qualitative research means the thesis inves...

  2. Multigeneration family with dominant SPG30 hereditary spastic paraplegia.

    Science.gov (United States)

    Roda, Ricardo H; Schindler, Alice B; Blackstone, Craig

    2017-11-01

    Autosomal recessive KIF1A missense mutations cause hereditary spastic paraplegia (HSP) type SPG30, while recessive truncations lead to sensory and autonomic neuropathy (HSN2C) and many de novo missense mutations are associated with cognitive impairment. Here, we describe family members across three generations with pure HSP. A heterozygous p.Ser69Leu KIF1A mutation segregates with those afflicted. The same variant was previously reported in a Finnish father and son with pure HSP as well as four members of a Sicilian kindred with more intrafamilial phenotypic variability. This further validates the pathogenicity of the p.Ser69Leu mutation and suggests that it may represent a mutation hot spot.

  3. Monitoring of radioactivity in the environs of Finnish nuclear power stations in 1987

    International Nuclear Information System (INIS)

    Sjoeblom, K.-L.; Klemola, S.; Ilus, E.; Arvela, H.; Blomqvist, L.

    1989-06-01

    Results of the environmental programmes for monitoring radioactive contamination around Finnish nuclear power plants in 1987 are reported. Fallout from the Chernobyl accident, which took place in April 1986, was still dominating the artificial radiation situation in Finland. Thus, large amounts of 137 Cs and other long-lived fallout nuclides predominated in the environmental samples taken in the vicinity of nuclear power plants. The extremely small airborne releases from Finnish nuclear power plants were almost totally covered by fallout nuclides. The somewhat higher aquatic releases were easier to distinguish, and it was possible to follow their spread in the marine environment. The contribution of locally discharged nuclides to radiation doses of the population was insignificant

  4. Finnish Cooperating Physics Teachers' Conceptions of Physics Teachers' Teacher Knowledge

    Science.gov (United States)

    Asikainen, Mervi A.; Hirvonen, Pekka E.

    2010-01-01

    This article examines Finnish cooperating physics teachers' conceptions of teacher knowledge in physics. Six experienced teachers were interviewed. The data was analyzed to form categories concerning the basis of teacher knowledge, and the tradition of German Didaktik and Shulman's theory of teacher knowledge were used in order to understand the…

  5. Implementing the Finnish Literacy Curriculum in a First-Grade Classroom

    Science.gov (United States)

    Räisänen, Sari; Korkeamäki, Riitta-Liisa

    2015-01-01

    This study investigated the first author's process of implementing new literacy practices as a teacher in a Finnish first-grade classroom from a poststructuralist perspective by using nexus analysis (NA). We concentrated on two essential concepts in NA, Bourdieu's habitus and Goffman's interaction order, which we linked to Grundy's curriculum…

  6. Exploring Finnish university students' perceived level of critical thinking

    OpenAIRE

    Orszag, Aaron

    2015-01-01

    Critical thinking is believed to be a 21 st century skill that many employers consider crucial when hiring recent graduates. However, it is debated whether critical thinking should be taught in academic foreign language courses at the tertiary level, which primarily aim to develop students’ language and communication skills. This localized, exploratory research examines Finnish university students’ self-reported critical thinking skills a...

  7. Cyber risk management in the Finnish healthcare sector

    OpenAIRE

    Hellstén, Hanne

    2018-01-01

    Advances in technology and digitalization have been widely adopted by Finnish healthcare organizations. This development has led to improvements in the efficiency and outcomes of patient care, but has also exposed healthcare providers to new kinds of risks. Cyber risks are becoming an increasingly common occurrence in the healthcare sector, and can lead to serious consequences for patients and organizations alike. The significance of cyber risks within healthcare has been projected to grow...

  8. Comparison of knowledge, attitudes and behaviour regarding smoking among Estonian and Finnish physicians.

    Science.gov (United States)

    Pärna, Kersti; Rahu, Kaja; Barengo, Noël C; Rahu, Mati; Sandström, Patrick H; Jormanainen, Vesa J; Myllykangas, Markku T

    2005-01-01

    To compare smoking behaviour, attitudes and opinions towards smoking and smoking cessation among Estonian and Finnish physicians. A cross-sectional postal survey using a self-administered questionnaire was carried out among 2,480 Estonian and 2,075 Finnish physicians. Daily smoking prevalence was higher among Estonian physicians than among their Finnish counterparts in both male (18.6% and 6.7%) and female (6.6% and 3.6%). Compared to Estonia, physicians in Finland more often agreed that smoking is very harmful to their health, that trying to convince people to stop smoking is their responsibility and that smoking prevention should be part of the normal and special training of health professionals. In both countries, non-smoking physicians held more unfavourable attitudes towards smoking than those who were smoking. Physicians' own smoking patterns and quitting behaviour are important because physicians serve as models for their patients and play a key role in the reinforcement of smoke-free health facilities. These results remain a challenge to medical educators, especially in Estonia. Estonia needs to improve medical education in terms of motivating physicians to ask about the smoking patterns of their patients and of training medical students and resident physicians to counsel their patients to stop smoking.

  9. Genetic variation of loin and ham quality in Finnish Landrace and Large White pigs

    Directory of Open Access Journals (Sweden)

    M-L. SEVÓN-AIMONEN

    2008-12-01

    Full Text Available Selection potential for meat quality of economically important loin (longissimus and ham muscles (adductor, semimembranosus, biceps femoris has been assessed. Ultimate pH (pHu, meat colour (lightness, redness and yellowness, drip loss and two visually scored colour traits were recorded from 483 Finnish Landrace and 494 Finnish Large White station test pigs in a half-sib design. A univariate restricted maximum likelihood procedure was used to estimate variance components. The statistical model contained age at beginning of test, sex and time lapse from slaughter to dissection as fixed effects and slaughter batch, common environment of littermates and additive genetic effect of the animal as random effects. The average pHu values in adductor and semispinalis were between 5.6 and 6.1. The pHu were on average 5.4 and 5.5 in longissimus and semimembranosus respectively, with the latter two being lower than optimum values of 5.6 to 5.9. Lightness for semimembranosus turned to be clearly lighter (62 than for other muscles. Lightness for longissimus (56 was slightly lighter than optimum (from 48 to 54. The heritability varied from zero to 0.45 for pHu, from 0.02 to 0.34 for lightness, from 0.17 to 0.56 for redness, from zero to 0.28 for yellowness and from 0.05 to 0.16 for drip loss. Heritability for redness values was considerably higher than heritability for other meat quality traits. The heritability of quality traits spoke for possibilities for genetic improvement of meat quality. Genetic correlations between quality traits (pHu and lightness and average daily gain varied strongly among breeds and muscles. Genetic correlations between meat-% and pHu were in most cases high and unfavourable (rg from –0.36 to –0.68 except in longissimus, where it was 0.11. Genetic correlations between meat-% and lightness were unfavourable in Finnish Large White (from 0.47 to 0.92 but in Finnish Landrace estimates varied among muscles (from –0.40 to 0.47. Due to

  10. DIGITALISATION IN FINNISH MUSEUMS

    Directory of Open Access Journals (Sweden)

    Magdalena Laine-Zamojska

    2014-01-01

    Full Text Available W artykule omówiono generalny obraz digitalizacji w fińskim sektorze muzealnym. Przedstawiono szacunkowe liczby dotyczące digitalizacji dziedzictwa kulturowego na podstawie przeprowadzonych statystycznych badań, oraz zaprezentowano wiele projektów związanych z ucyfrowieniem fińskich muzeów.\tFiński sektor muzealny jest niezwykle zróżnicowany, podobnie jak stopień skatalogowania i zdigitalizowania kolekcji. W projektach rozwojowych aktywnie uczestniczy cały sektor muzealny. W ostatnich latach, dzięki wielu inicjatywom i badaniom udało się uzyskać szczegółowy obraz fińskiego sektora muzealnego. Największą inicjatywą jest projekt utworzenia Narodowej Biblioteki Cyfrowej, podlegający Ministerstwu Edukacji i Kultury. Celem projektu jest połączenie i udostępnienie zasobów z instytucji pamięci (bibliotek, archiwów i muzeów. Towarzyszą mu rozległe projekty digitalizacji.\tW związku z ogromną różnorodnością systemów do zarządzania kolekcją i praktykami katalogowymi w muzeach, w 2011 r. Państwowy Urząd Muzealny (Museovirasto / National Board of Antiquities, Fiński Związek Muzeów (Suomen museoliitto / Finnish Museums Association i Państwowa Galeria Sztuki (Valtion taidemuseo / Finnish National Gallery zainicjowały projekt Muzeum2015 (Museo2015 / Museum2015. Jego głównymi celami są: unifikacja procesów związanych z zarządzaniem kolekcją, stworzenie architektury korporacyjnej dla zarządzania muzealną kolekcją, stworzenie modelu zarządzania dla architektury korporacyjnej, oraz określenie i stworzenie warunków do zakupu i implementacji ogólnofińskiego systemu zarządzania kolekcją.\tRozwój cyfrowych narzędzi dla najmniejszych, prowadzonych przez wolontariuszy, muzeów lokalnych jest jednym z celów projektu badawczego ViMuseo, prowadzonego na Uniwersytecie w Jyväskylä (Jyväskylän yliopisto / University of Jyväskylä.

  11. The finnish guide to radon-resistant homes

    International Nuclear Information System (INIS)

    Arvela, H.

    2006-01-01

    Full text of publication follows: New regulations of the National Finnish Building Code require consideration of radon risks and as a main rule radon technical design in the building permission documents. Slab-on-grade is the prevalent substructure in Finnish low-rise residential buildings. Building statistics show that the prevalent practices in foundation construction promote the flow of radon-bearing soil air into living spaces. Without prevention the normal practices would result in high indoor radon concentrations in Finland. In wide areas more than 50% of houses exceed the reference level of 200 Bq/m 3 given for new buildings. The new guide published in 2003 requires installation of protective sheet in the slab-on-ground foundation and a preparatory radon piping. A protective sheet of durable reinforced bitumen felt with a width of 50 - 100 cm should be installed in the slab-foundation wall joint. Careful sealing of lead-troughs plays also an important role. In the case the sealing work does not result in low indoor radon concentration, the radon piping should be activated through radon-fan installation. Careful implementation of the sealing work reduces indoor radon concentration to a level of less than 50 Bq/m 3 , also in areas where the normal building practices result in indoor radon concentrations exceeding the reference level of 200 Bq/m 3 in more than 50% of new houses. Recent experiences from the implementation of the guide will be considered. (author)

  12. Molecular genetic approach for screening of hereditary non-polyposis colorectal cancer

    Directory of Open Access Journals (Sweden)

    Metka Ravnik-Glavač

    2005-07-01

    Full Text Available Background: The main goal of knowledge concerning human diseases is to transfer as much as possible useful information into clinical applications. Hereditary non-polyposis colorectal cancer (HNPCC is the most common autosomal dominant inherited predisposition for colorectal cancer, accounting for 1–2% of all bowel cancer. The only way to diagnose HNPCC is by a family history consistent with the disease defined by International Collaborative Group on HNPCC (Amsterdam criteria I and II. The main molecular cause of HNPCC is a constitutional mutation in one of the mismatch repair (MMR genes. Since HNPCC mutations have been detected also in families that did not fulfil the Amsterdam criteria, molecular genetic characteristics of HNPCC cancers have been proposed as valuable first step in HNPCC identification. Microsatellite instability is present in about 90% of cancers of HNPCC patients. However, of all MSI colorectal cancers 80– 90% are sporadic. Several molecular mechanisms have been uncovered that enable distinguishing to some extent between sporadic and HNPCC cancers with MSI including hypermethylation of hMLH1 promoter and frequent mutations in BAX and TGFBR2 in sporadic CRC with MSI-H.Conclusions: The determination of MSI status and careful separation of MSI positive colorectal cancer into sporadic MSIL, sporadic MSI-H, and HNPCC MSI-H followed by mutation detection in MMR genes is important for prevention, screening and management of colorectal cancer. In some studies we and others have already shown that large-scale molecular genetic analysis for HNPCC can be done and is sensitive enough to approve population screening. Population screening includes also colonoscopy which is restricted only to the obligate carriers of the mutation. This enables that the disease is detected in earlier stages which would greatly decrease medical treatment costs and most importantly decrease mortality. In Slovenia we have started population screening based

  13. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1991-12-01

    The Finnish nuclear power plant units Loviisa 1 and 2 as well as TVO 1 and II were in operation for almost the whole second quarter of 1991. The load factor average was 87.4 %. In consequence of a fire, which broke out in the switchgear building, connections to both external grids were lost and TVO II relied on power supplied by four back-up diesels for 7.5 hrs. The event is classified as Level 2 on the International Nuclear Event Scale. The process of examining the non-leaking fuel bundles removed from the Loviisa nuclear reactors has continued. The examinations have revealed, so far, that the uppermost spacing lattices of the bundles exhibit deformations similar to those detected in the leaking fuel bundles removed from the reactors. This event is classified as Level 1 on the International Nuclear Event Scale. Other events in this quarter which are classified according to the International Nuclear Event Scale are Level Zero (Below Scale) on the Scale. The Finnish Centre for Radiation and Nuclear Safety has assessed the safety of the Loviisa and Olkiluoto nuclear power plants based on the new regulations issued on 14.2.1991 by the Council of State. The safety regulations are much more stringent than those in force when the Loviisa and Olkiluoto nuclear power plants were built. The assessment indicated that the TVO nuclear power plant meets these safety regulations. The Loviisa nuclear power plant meets the requirements with the exception of certain requirements related to the ensuring of safety functions and provision for accidents. At the Loviisa nuclear power plant there are several projects under consideration to enhance safety

  14. Displaying Now-Understanding: The Finnish Change-of-State Token "aa"

    Science.gov (United States)

    Koivisto, Aino

    2015-01-01

    This article discusses the use of the Finnish change-of-state token "aa" that has previously not been identified. The central claim is that even though "aa" indicates a cognitive shift experienced by the speaker, it does not function as a receipt of new information. Instead, the token "aa" indicates that the speaker…

  15. Cause-specific mortality in Finnish ferrochromium and stainless steel production workers.

    Science.gov (United States)

    Huvinen, M; Pukkala, E

    2016-04-01

    Although stainless steel has been produced for more than a hundred years, exposure-related mortality data for production workers are limited. To describe cause-specific mortality in Finnish ferrochromium and stainless steel workers. We studied Finnish stainless steel production chain workers employed between 1967 and 2004, from chromite mining to cold rolling of stainless steel, divided into sub-cohorts by production units with specific exposure patterns. We obtained causes of death for the years 1971-2012 from Statistics Finland. We calculated standardized mortality ratios (SMRs) as ratios of observed and expected numbers of deaths based on population mortality rates of the same region. Among 8088 workers studied, overall mortality was significantly decreased (SMR 0.77; 95% confidence interval [CI] 0.70-0.84), largely due to low mortality from diseases of the circulatory system (SMR 0.71; 95% CI 0.61-0.81). In chromite mine, stainless steel melting shop and metallurgical laboratory workers, the SMR for circulatory disease was below 0.4 (SMR 0.33; 95% CI 0.07-0.95, SMR 0.22; 95% CI 0.05-0.65 and SMR 0.16; 95% CI 0.00-0.90, respectively). Mortality from accidents (SMR 0.84; 95% CI 0.67-1.04) and suicides (SMR 0.72; 95% CI 0.56-0.91) was also lower than in the reference population. Working in the Finnish ferrochromium and stainless steel industry appears not to be associated with increased mortality. © The Author 2015. Published by Oxford University Press on behalf of the Society of Occupational Medicine.

  16. Finnish support programme to IAEA safeguards. Annual report 1993; Suomen tukiohjelma IAEA:n safeguards-valvonnalle. Vuoden 1993 toimintakertomus

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, M [ed.

    1994-03-01

    Implementation of the Finnish Support Programme to IAEA Safeguards (FINSP) during the calender year in question is summarized. FINSP is carried out through separate tasks related to development of non-destructive measurement methods (NDA methods) for verification of nuclear material, training and expert services to the IAEA. In addition to a Finnish summary, the report includes detailed description of each task in English. (editor).

  17. Finnish support programme to IAEA safeguards. Annual report 1992; Suomen tukiohjelma IAEA:n safeguards-valvonnalle. Vuoden 1992 toimintakertomus

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, M [ed.

    1993-04-01

    Implementation of the Finnish Support Programme to IAEA Safeguards (FINSP) during the calender year in question is summarized. FINSP is carried out through separate tasks related to development of non-destructive measurement methods (NDA methods) for verification of nuclear material, training and expert services to the IAEA. In addition to a Finnish summary, the report includes detailed description of each task in English. (editor).

  18. Methane oxidation in soil profiles of Dutch and Finnish coniferous forests with different soil texture and atmospheric nitrogen deposition

    NARCIS (Netherlands)

    Saari, A.; Martikainen, P.J.; Ferm, A.; Ruuskanen, J.; De Boer, W.; Troelstra, S.R.; Laanbroek, H.J.

    1997-01-01

    We studied methane oxidation capacity in soil profiles of Dutch and Finnish coniferous forests. The Finnish sites (n = 9) had nitrogen depositions from 3 to 36 kg N ha(-1) a(-1). The deposition of N on the Dutch sites (n = 13) was higher ranging from 50 to 92 kg N ha(-1) a(-1). The Dutch sites had

  19. Applying open innovation in business strategies : Evidence from Finnish software firms

    NARCIS (Netherlands)

    Harison, Elad; Koski, Heli

    Our study aims at shedding light on the innovative business strategies in the software sector and understanding better the economics that underlies the supply of Open Source Software (OSS). We use survey data collected from 170 Finnish software companies to investigate how different properties of

  20. Association of the World War II Finnish Evacuation of Children With Psychiatric Hospitalization in the Next Generation.

    Science.gov (United States)

    Santavirta, Torsten; Santavirta, Nina; Gilman, Stephen E

    2018-01-01

    Although there is evidence that adverse childhood experiences are associated with worse mental health in adulthood, scarce evidence is available regarding an emerging concern that the next generation might also be affected. To compare the risk of psychiatric hospitalization in cousins whose parents were vs were not exposed to the Finnish evacuation policy that involved a mean 2-year stay with a Swedish foster family. This multigenerational, population-based cohort study of Finnish individuals and their siblings born between January 1, 1933, and December 31, 1944, analyzed the association of evacuee status as a child during World War II in the first generation with the risk of psychiatric hospitalization among offspring in the second generation. Evacuee status during World War II was determined using the Finnish National Archive's registry of participants in the Finnish evacuation. Data on evacuee status were linked to the psychiatric diagnoses in the Finnish Hospital Discharge Register from January 1, 1971, through December 31, 2012, for offspring (n = 93 391) born between January 1, 1950, and December 31, 2010. Sex-specific Cox proportional hazards regression models were used to estimate hazard ratios for risk of psychiatric hospitalization during the follow-up period. Because offspring of evacuees and their nonevacuated siblings are cousins, the Cox proportional hazards regression models included fixed effects to adjust for confounding factors in families. Data analysis was performed from June 15, 2016, to August 26, 2017. Parental participation in the evacuation during World War II (coded 1 for parents who were evacuated and placed in foster care and 0 for those not evacuated). Offspring's initial admission to the hospital for a psychiatric disorder, obtained from the Finnish Hospital Discharge Register from January 1, 1971, through December 31, 2012. Of the 93 391 study persons, 45 955 (49.2%) were women and 47 436 (50.8) were men; mean (SD) age in

  1. Comparing Russian and Finnish standards of water purification

    OpenAIRE

    Maria, Pupkova

    2012-01-01

    The subject of this thesis is water purification. The first aim of this thesis is to consider different ways of water purification. The second aim is to compare Finnish and Russian standards of water purification. The third one is to show water purification methods on the pattern of Mikkeli water purification plan. Water purification methods of water intended for human consumption will be described.Combined tables will be done according to the quality requirement of drinking water of both,...

  2. The Finnish research programme on climate change SILMU

    International Nuclear Information System (INIS)

    Heikinheimo, P.; Kanninen, M.

    1995-01-01

    SILMU, which runs from 1990 to 1995, aims at studying climate change and its impacts. It also seeks to provide information to Finnish policy makers on adaptation and mitigation. The topics range from air chemistry to sociology, and the total number of projects is 74. Interim evaluation of the programme was carried out in 1992. During the second half of SILMU, 10% of the total budget (total: 14 Million ECU) has been devoted to programme integration. 8 refs

  3. Creating visual guidelines for a Finnish fashion brand

    OpenAIRE

    Morozova, Elizaveta

    2017-01-01

    Visual communication is an essential part of branding. Visual elements like logo, brand colours, and typography create associations with a brand and make it distinctive. Graphic design is a tool for visual communication that allows creating aesthetic and functional visual elements that convey some messages. The client of this thesis is a Finnish fashion company that does not have clear and consistent visual image, and the goal is to create it based on company’s values and desired image...

  4. Genome-Wide Meta-Analysis of Sciatica in Finnish Population.

    Science.gov (United States)

    Lemmelä, Susanna; Solovieva, Svetlana; Shiri, Rahman; Benner, Christian; Heliövaara, Markku; Kettunen, Johannes; Anttila, Verneri; Ripatti, Samuli; Perola, Markus; Seppälä, Ilkka; Juonala, Markus; Kähönen, Mika; Salomaa, Veikko; Viikari, Jorma; Raitakari, Olli T; Lehtimäki, Terho; Palotie, Aarno; Viikari-Juntura, Eira; Husgafvel-Pursiainen, Kirsti

    2016-01-01

    Sciatica or the sciatic syndrome is a common and often disabling low back disorder in the working-age population. It has a relatively high heritability but poorly understood molecular mechanisms. The Finnish population is a genetic isolate where small founder population and bottleneck events have led to enrichment of certain rare and low frequency variants. We performed here the first genome-wide association (GWAS) and meta-analysis of sciatica. The meta-analysis was conducted across two GWAS covering 291 Finnish sciatica cases and 3671 controls genotyped and imputed at 7.7 million autosomal variants. The most promising loci (psciatica patients and 18,489 controls. We identified five intragenic variants, with relatively low frequencies, at two novel loci associated with sciatica at genome-wide significance. These included chr9:14344410:I (rs71321981) at 9p22.3 (NFIB gene; p = 1.30x10-8, MAF = 0.08) and four variants at 15q21.2: rs145901849, rs80035109, rs190200374 and rs117458827 (MYO5A; p = 1.34x10-8, MAF = 0.06; p = 2.32x10-8, MAF = 0.07; p = 3.85x10-8, MAF = 0.06; p = 4.78x10-8, MAF = 0.07, respectively). The most significant association in the meta-analysis, a single base insertion rs71321981 within the regulatory region of the transcription factor NFIB, replicated in an independent Finnish population sample (p = 0.04). Despite identifying 15q21.2 as a promising locus, we were not able to replicate it. It was differentiated; the lead variants within 15q21.2 were more frequent in Finland (6-7%) than in other European populations (1-2%). Imputation accuracies of the three significantly associated variants (chr9:14344410:I, rs190200374, and rs80035109) were validated by genotyping. In summary, our results suggest a novel locus, 9p22.3 (NFIB), which may be involved in susceptibility to sciatica. In addition, another locus, 15q21.2, emerged as a promising one, but failed to replicate.

  5. Finnish Baby Boomers and the Emergence of the Third Age

    Directory of Open Access Journals (Sweden)

    Antti Karisto

    2008-04-01

    Full Text Available This paper examines the lives of baby boomers in Finland, and is based on several studies previously published in Finnish. The article considers the particular characteristics of this group of baby boomers. It then discusses whether the baby boom cohorts can also be called a generation. Following this, the life course of the boomer generation is contrasted with various images that have appeared in the media and elsewhere about their lives. Boomers have been presented as a radical’ or ‘selfish’ generation. This article proposes two new themes: boomers as a crossroads generation and boomers as a bridging generation. The paper also considers the emergence of the third age as approached from a generational perspective. The third age has been defined as a generational field underpinned by agency and consumption, with its roots in the youth culture of the post-war decades. This characterization is also highly relevant to the Finnish case, but needs to be elaborated by taking into account socio-historical knowledge of the distinctive life course of the boomer generation.

  6. Monitoring of radioactivity in the environs of Finnish nuclear power stations in 1986

    International Nuclear Information System (INIS)

    Ilus, E.; Sjoeblom, K.L.; Aaltonen, H.; Klemola, S.; Arvela, H.

    1987-06-01

    Results of the environmental programmes monitoring radioactivity around the Finnish nuclear power stations in 1986 are reported. After the end of April the fallout nuclides from the Chernobyl accident predominated in all samples taken from the environs of the two power stations Loviisa and Olkiluoto. Radionuclides originating from the Finnish power stations were detected mainly in samples taken from the aquatic environment. The concentrations of the locally discharged nuclides were very low in comparison with the fallout nuclides and their impact on the radiation doses of the population was insignificant. Both nuclear power stations are situated in the main fallout area in Finland. The results of these large monitoring programmes give a good picture of the behaviour of the Chernobyl fallout in the specific areas in Finland

  7. Quality of the relationship between origin of childhood perception of attachment and outcome of attachment associated with diagnosis of PTSD in adult Finnish war children and Finnish combat veterans from World War II (1939-1945) - DSM-IV applications of the attachment theory.

    Science.gov (United States)

    Andersson, Pentti Kalevi

    2015-06-01

    Using diagnoses exclusively, comparable evaluations of the empirical evidence relevant to the content can be made. The term holocaust survivor syndrome according to the DSM-IV classification encompasses people with diagnoses of posttraumatic stress disorders and psychopathological symptoms exposed to the Nazi genocide from 1933-1945 identified by Natan Kellermann, AMCHA, Israel (1999). The relationships between disorders of affectionate parenting and the development of dysfunctional models on one hand, and various psychopathological disorders on the other hand were investigated. Multi-axial assessment based on PTSD diagnosis (APA, 2000) with DSM-IV classification criteria of holocaust survivor syndrome and child survivor syndrome earlier found in holocaust survivors was used as criteria for comparison among Finnish sub-populations. Symptoms similar to those previously described in association with holocaust survivor syndrome and child survivor syndrome were found in the population of Finnish people who had been displaced as children between 1939-1945. Complex PTSD syndrome is found among survivors of prolonged or repeated trauma who have coping strategies intended to assist their mental survival. Surviving Finnish child evacuees had symptoms at similar level to those reported among holocaust survivors, though Finnish combat veterans exhibited good mental adjustment with secure attachment.

  8. Methane oxidation in soil profiles of Dutch and Finnish coniferous forests with different soil texture and atmospheric nitrogen deposition

    NARCIS (Netherlands)

    Saari, A.; Martikainen, P.J.; Ferm, A.; Ruuskanen, J.; Boer, W. de; Troelstra, S.R.; Laanbroek, H.J.

    1997-01-01

    We studied methane oxidation capacity in soil profiles of Dutch and Finnish coniferous forests. The Finnish sites (n = 9) had nitrogen depositions from 3 to 36 kg N ha⁻¹ a⁻¹. The deposition of N on the Dutch sites (n = 13) was higher ranging from 50 to 92 kg N ha⁻¹ a⁻¹. The Dutch sites had also

  9. Anabolic-androgenic steroid use among young Finnish males.

    Science.gov (United States)

    Mattila, V M; Rimpelä, A; Jormanainen, V; Sahi, T; Pihlajamäki, H

    2010-04-01

    The aim of the present study was to describe the lifetime occurrence and associated factors of anabolic-androgenic steroids (AAS) among young Finnish males. Of the 10 829 male conscripts (median age 19), 10 396 (96%) answered a questionnaire during the first days of their conscription in the years 2001-2007. The main outcome was lifetime AAS use. We also studied associations between 13 socioeconomic, health, and health behavioral background variables and AAS use by logistic regression. Eighty-nine (0.9%) respondents reported having used AAS. In addition, 26 (0.3%) respondents reported that they would use AAS if they could obtain them. In multivariate analysis, which included all significant variables and age, the strongest associated factors were weight training at fitness centers more than three times a week [odds ratio (OR) 11.8; 95% confidence interval (CI): 7.1-19.6], low educational status (OR 3.7; 95% CI: 2.0-7.0), and weekly drunkenness as drinking style (OR 2.4; 95% CI: 1.4-4.5). Sports other than weight training were not associated with AAS in our sample. The use of AAS is relatively uncommon among Finnish males. It is strongly associated with weight training at fitness centers but also with lower educational status and a drunkenness-oriented lifestyle. Prevention should be targeted at those males participating in weight training.

  10. Healthcare professionals' work engagement in Finnish university hospitals.

    Science.gov (United States)

    Lepistö, Sari; Alanen, Seija; Aalto, Pirjo; Järvinen, Päivi; Leino, Kaija; Mattila, Elina; Kaunonen, Marja

    2017-10-10

    Concerns about the sufficiency and dedication of the healthcare workforce have arisen as the baby boomer generation is retiring and the generation Y might have different working environment demands. To describe the association between work engagement of healthcare professionals' and its background factors at five Finnish university hospitals. Survey data were collected from nurses, physicians and administrative staff (n = 561) at all five university hospitals in Finland. Data were collected using an electronic questionnaire that comprised the Utrecht Work Engagement Scale (9 items) and 13 questions regarding the respondents' backgrounds. Descriptive and correlational analyses were used to examine the data. Most respondents were female (85%) and nursing staff (72%). Baby boomers (49%) were the largest generational cohort. The work engagement composite mean for the total sample was 5.0, indicating high work engagement. Significant differences in work engagement existed only among sex and age groups. The highest work engagement scores were among administrative staff. Work engagement among healthcare professionals in Finnish university hospitals is high. High work engagement might be explained by suitable job resources and challenges, as well as opportunities provided by a frontline care environment. Attention should especially be paid to meeting the needs of young people entering the workforce to strengthen their dedication and absorption. © 2017 Nordic College of Caring Science.

  11. Sex-Free and Sex-Related Components of the Eysenck Personality Questionnaire (EPQ Neuroticism Scale among Finnish and Turkish Students

    Directory of Open Access Journals (Sweden)

    Timo Lajunen

    2018-03-01

    Full Text Available Previous studies have suggested that the Neuroticism scale (N of the Eysenck Personality Questionnaire (EPQ reflects two different dimensions, of which the first is sex-related (N-S and the second sex-free (N-A. The N-S component is characterized by social sensitivity and worry while N-A reflects moodiness, irritability and boredom. The purpose of this study was to investigate the internal structure of the N scale in samples of 320 Finnish and 230 Turkish students. The bi-dimensional structure suggested by Francis had an acceptable fit to data in the Finnish and Turkish samples. Higher N-S and N scores correlated with being a woman in the Turkish sample. Neither N nor N-S scores were related to sex in the Finnish sample. ANOVA results showed the main effect of sex on N and N-S scores and the main effect of culture (Finnish vs. Turkish on N and N-A. Turkish women scored higher in N and N-S scales than the other groups. The possible cultural and social reasons for the sex differences on the N scale score were discussed.

  12. Internationalization of Finnish Technology Startups : Case: Goodwille Ltd

    OpenAIRE

    Goncalves, Miriam

    2014-01-01

    The United Kingdom is a large European market that offers vast market potential for companies that enter it. Finnish start-up companies are especially drawn to this market by the venture capital opportunities. A presence in the United Kingdom is necessary for companies that want to become truly international. The sponsor of the thesis is Goodwille Ltd., a British company that provides services to foreign companies who want to start or expand their business in the UK. Goodwille’s newly se...

  13. Gender differences in health information behaviour: a Finnish population-based survey.

    Science.gov (United States)

    Ek, Stefan

    2015-09-01

    Narrowing the gaps in health outcomes, including those between men and women, has been a pronounced goal on the agenda of the Finnish health authorities since the mid-1980s. But still there is a huge gap in favour of women when it comes to life expectancy at birth. People's health information behaviour, that is how people seek, obtain, evaluate, categorize and use relevant health-related information to perform desired health behaviours, is a critical prerequisite to appropriate and consistent performances of these behaviours. With respect to gender, it has been noted that men often are unwilling and lack the motivation to engage with health-related information. The purpose of this study was to investigate how gender affects health information behaviour in the Finnish population aged 18-65 years. The survey data were collected via a questionnaire which was posted to a representative cross section consisting of 1500 Finnish citizens. The statistical analysis consists of ANOVA F-tests and Fisher's exact tests. The results show that women were more interested in and reported much more active seeking of health-related information, paid more attention to potential worldwide pandemics and were much more attentive as to how the goods they purchase in everyday life affect their health than men did. Women also reported receiving far more informal health-related information from close family members, other kin and friends/workmates than men did. Thus, to succeed in public health promotion and interventions the measures taken should be much more sensitive to the gender gap in health information behaviour. © The Author (2013). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. The role of the Finnish Meteorological Institute

    International Nuclear Information System (INIS)

    Savolainen, A.L.; Valkama, I.

    1993-01-01

    The Finnish Meteorological Institute is responsible for the dispersion forecasts for the radiation control in Finland. In addition to the normal weather forecasts the duty forecaster has the work station based three dimensional trajectory model and the short range dispersion model YDINO at his disposal. For expert use, dispersion and dose model TRADOS is available. The TRADOS, developed by the Finnish Meteorological Institute and by the Technical Research Centre of Finland, includes a meteorological data base that utilizes the numerical forecasts of the High Resolution Limited Area Model (HIRLAM) weather prediction model. The transport is described by three-dimensional air-parcel trajectories. For each time step the integrated air concentrations as well as dry and wet deposition for selected groups of radionuclides are computed. In the operational emergency application only external dose rates are computed. In the statistical version also individual and population dose estimates via several external and internal pathways can be made. The TRADOS is currently run under two separate user interfaces. The trajectory and dispersion model interface includes ready-made lists of the nuclear power plants and other installations. The dose model has a set of release terms for several groups of radionuclides. There is also a graphical module that enables the computed results to be presented in grid or also isolines. A new graphical user interface and presentation lay-outs redesigned as visual and end-user friendly as possible and with the aim of possible and with the aim of possible adoption as a Nordic standard will be installed in the near future. (orig.)

  15. Future of energy efficiency and carbon dioxide emissions of Finnish road freight transport

    Energy Technology Data Exchange (ETDEWEB)

    Liimatainen, H.

    2013-05-15

    The targets to reduce the carbon dioxide emissions to mitigate climate change are as much applicable to the road freight transport sector as they are to all other sectors of society. The aim of this research is to support the initiatives of the Finnish government for improving the energy efficiency and reducing the CO{sub 2} emissions of road freight transport. This is done by forecasting the future development and giving the policy makers guidance on effective measures for promoting road freight energy efficiency and CO{sub 2} reduction. In the study a new method was introduced for connecting the fuel consumption data and goods transport data gathered from the official Finnish road statistics. This method enabled a detailed analysis of the interrelations between the economy, road freight transport, energy consumption and emissions. This analysis was conducted for the years 1995-2010 and the results were used as background information in the Delphi panel of experts. The experts estimated the development of the Finnish road freight sector to the year 2030. Furthermore, a web-based survey was conducted among Finnish road freight hauliers and shippers in order to explore the attitudes and measures related to the energy efficiency. Expert panel workshops were also organised to identify obstacles for the development of the energy efficiency of road freight transport as well as a wide selection of measures to overcome them. The results indicate that the economic development of different branches has a great effect on the energy efficiency and carbon dioxide emissions of road freight transport. Reaching the carbon emission target for the year 2030 is possible in the light of the scenarios which were formed based on expert forecasts. However, the target can be achieved with very different development paths, e.g. the structure of the national economy and the volume of transport seem to vary widely in the different scenarios. In the proposed recommendations on the measures

  16. Attitudes towards schizophrenia on YouTube: A content analysis of Finnish and Greek videos.

    Science.gov (United States)

    Athanasopoulou, Christina; Suni, Sanna; Hätönen, Heli; Apostolakis, Ioannis; Lionis, Christos; Välimäki, Maritta

    2016-01-01

    To investigate attitudes towards schizophrenia and people with schizophrenia presented in YouTube videos. We searched YouTube using the search terms "schizophrenia" and "psychosis" in Finnish and Greek language on April 3rd, 2013. The first 20 videos from each search (N = 80) were retrieved. Deductive content analysis was first applied for coding and data interpretation and it was followed by descriptive statistical analysis. A total of 52 videos were analyzed (65%). The majority of the videos were in the "Music" category (50%, n = 26). Most of the videos (83%, n = 43) tended to present schizophrenia in a negative way, while less than a fifth (17%, n = 9) presented schizophrenia in a positive or neutral way. Specifically, the most common negative attitude towards schizophrenia was dangerousness (29%, n = 15), while the most often identified positive attitude was objective, medically appropriate beliefs (21%, n = 11). All attitudes identified were similarly present in the Finnish and Greek videos, without any statistically significant difference. Negative presentations of schizophrenia are most likely to be accessed when searching YouTube for schizophrenia in Finnish and Greek language. More research is needed to investigate to what extent, if any, YouTube viewers' attitudes are affected by the videos they watch.

  17. The fifth Finnish national aerosol symposium

    International Nuclear Information System (INIS)

    Mikkanen, P.; Haemeri, K.; Kauppinen, E.

    1993-01-01

    The Fifth Finnish Aerosol Symposium was held June 1-3, 1993. Symposium is jointly organized by FAAR, Aerosol Technology Group of Technical Research Centre of Finland and Helsinki University, Department of Physics. Aerosols, the suspensions of solid and liquid particles and gases, are receiving increasing importance in many areas of science and technology. These include industrial hygiene, ambient and indoor air pollution, pollution control technologies, cloud physics, nuclear safety engineering, combustion science and engineering, clean manufacturing technologies and material processing. The importance of aerosol issues during the development of advanced fuel conversion and material processing technologies can be realized when looking at the numerous papers presented on these topics at the Symposium

  18. Peroxisomal proliferator activated receptor-γ deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3

    Directory of Open Access Journals (Sweden)

    Cao Henian

    2006-01-01

    Full Text Available Abstract Background Familial partial lipodystrophy (Dunnigan type 3 (FPLD3, Mendelian Inheritance in Man [MIM] 604367 results from heterozygous mutations in PPARG encoding peroxisomal proliferator-activated receptor-γ. Both dominant-negative and haploinsufficiency mechanisms have been suggested for this condition. Methods We present a Canadian FPLD3 kindred with an affected mother who had loss of fat on arms and legs, but no increase in facial, neck, suprascapular or abdominal fat. She had profound insulin resistance, diabetes, severe hypertriglyceridemia and relapsing pancreatitis, while her pre-pubescent daughter had normal fat distribution but elevated plasma triglycerides and C-peptide and depressed high-density lipoprotein cholesterol. Results The mother and daughter were each heterozygous for PPARG nonsense mutation Y355X, whose protein product in vitro was transcriptionally inactive with no dominant-negative activity against the wild-type receptor. In addition the mutant protein appeared to be markedly unstable. Conclusion Taken together with previous studies of human PPARG mutations, these findings suggest that PPAR-γ deficiency due either to haploinsufficiency or to substantial activity loss due to dominant negative interference of the normal allele product's function can each contribute to the FPLD3 phenotype.

  19. Intersectionality in Finnish adult education research: insights from the journal Aikuiskasvatus 2010-2016

    Directory of Open Access Journals (Sweden)

    Seija Keskitalo-Foley

    2017-11-01

    Full Text Available The article studies intersectionality in Finnish research on adult education. Specifically, we investigate the kinds of discussions on differences and their relations that are going on in such research. To this end we seek to identify intersectional approaches in the articles published in the journal Aikuiskasvatus between 2010 and 2016, a period marked by an increase in multiculturalism and social division as well as in gendered and sexual diversity in Finnish society. We understand intersectional differences as performative processes, not stable essences. Our study indicates that only few articles analysed intersectional differences explicitly. Implicitly recognised differences were mostly seen as givens. Categories such as ethnicity and race were found to be lacking in the data, but age, gender, social class, education, occupation and learning difficulties were discussed.

  20. Glocal Religion and Feeling at Home: Ethnography of Artistry in Finnish Orthodox Liturgy

    Directory of Open Access Journals (Sweden)

    Tatiana Tiaynen-Qadir

    2017-02-01

    Full Text Available This paper adapts a glocalization framework in a transnational, anthropological exploration of liturgy in the Orthodox Church of Finland (OCF. It draws on long-term ethnographic fieldwork and interviews with participants of liturgy from Finnish, Russian, and Greek cultural and linguistic backgrounds. The main argument of the paper is that generic processes of nationalization and transnationalization are not mutually exclusive in practitioners’ experiences of liturgy in OCF, but rather generate a glocal space that incorporates Finnish, Russian, Karelian, and Byzantine elements. Individuals artistically engage with glocal liturgy on sensorial, cognitive, social, and semantic levels. What is important for the participants is a therapeutic sense that comes from a feeling of ‘being at home’, metaphorically, spiritually, and literally. People’s ongoing, creative work constitutes Orthodoxy as their national and transnational home.

  1. Organization and Management of Continuing Education in German and Finnish Universities

    Science.gov (United States)

    Zawacki-Richter, Olaf; Knust, Michaela; Hanft, Anke

    2009-01-01

    In 2006, an international comparison study investigated the organization and management of university continuing education (UCE). The Finnish continuing education system proved to be especially advanced in this study. On the other hand, it became clear that Germany was still lagging behind in continuing education. In this article, German and…

  2. Relationship of Gender and Academic Achievement to Finnish Students' Intercultural Sensitivity

    Science.gov (United States)

    Holm, Kristiina; Nokelainen, Petri; Tirri, Kirsi

    2009-01-01

    This study examined the intercultural sensitivity of Finnish 12-16-year-old secondary school students (N=549) with a 23-item Intercultural Sensitivity Scale Questionnaire (ICSSQ). The ICSSQ is based on Bennett's (1993) Developmental Model of Intercultural Sensitivity (DMIS), which is a conceptual tool to situate certain reactions towards cultural…

  3. The ethnic gap in mobility: a comparison of Russian, Somali and Kurdish origin migrants and the general Finnish population

    Directory of Open Access Journals (Sweden)

    S. Rask

    2016-04-01

    Full Text Available Abstract Background Many ethnic minority populations have poorer health than the general population. However, there is limited knowledge on the possible ethnic gap in physical mobility. We aim to examine the prevalence of mobility limitations in working-age Russian, Somali and Kurdish origin migrants in comparison to the general population in Finland. We also determine whether the association between ethnic group and mobility limitation remains after taking into account socio-economic and health-related factors. Methods We used data from the Finnish Migrant Health and Wellbeing Study (Maamu and the Finnish Health 2011 Survey. The participants comprised 1880 persons aged 29–64 years. The age-adjusted prevalence of difficulties in various mobility tasks was calculated using predictive margins. Logistic regression analysis was used to examine the association between socio-economic, health- and migration-related factors and mobility limitation (self-reported difficulty in walking 500 m or stair climbing. The association between ethnic group and mobility limitation was calculated using logistic regression analysis. Results Mobility limitations were much more prevalent among Somali origin women (46 % and Kurdish origin men (32 % and women (57 % compared to men and women in the general Finnish population (5–12 %. In Russian origin men and women, the prevalence of mobility limitation (7–17 % was similar to the general Finnish population. Socio-economic and health-related factors, but not migration-related factors (time lived in Finland and language proficiency in Finnish or Swedish, were found to be associated with mobility limitation in the studied populations. Somali and Kurdish origin migrants were found to have increased odds for mobility limitation compared to the general Finnish population, even after adjusting for socio-economic and health-related factors (Somalis odds ratio [OR] 3.61; 95 % confidence interval [CI] 2.07–6.29, Kurds

  4. Discipline, availability of electronic resources and the use of Finnish National Electronic Library - FinELib

    Directory of Open Access Journals (Sweden)

    Sanna Torma

    2004-01-01

    Full Text Available This study elaborated relations between digital library use by university faculty, users' discipline and the availability of key resources in the Finnish National Electronic Library (FinELib, Finnish national digital library, by using nationwide representative survey data. The results show that the perceived availability of key electronic resources by researchers in FinELib was a stronger predictor of the frequency and purpose of use of its services than users' discipline. Regardless of discipline a good perceived provision of central resources led to a more frequent use of FinELib. The satisfaction with the services did not vary with the discipline, but with the perceived availability of resources.

  5. Topical review of the Finnish forest sector 1996

    International Nuclear Information System (INIS)

    Kuuluvainen, K.

    1996-01-01

    The present report is e review of the Finnish forest sector, made by several authors. The topics reviewed are: Economic trends of forest sector; The operational conditions of the forest sector; Development of the forest sector; Conjuncture reviews; Special topics including the certification of the forests, the forest reserves in Finland, the financial support forest economy, export prices of sawn timber and cellulose, raw-wood markets, forests and forest industry shares as targets for investments, recreational use of the state owned areas. (8 refs.)

  6. MAURITIUS: A SUNNY HOLIDAY DESTINATION FOR FINNISH PEOPLE

    OpenAIRE

    Goburdhun Bhurtun, Ishina

    2016-01-01

    The tourism market of Mauritius is booming as tourists are nowadays coming from many countries, thus improving the economy of the island. However, few Finnish tourists travel to Mauritius as it is still not well-known among Finns. The aim of this study is to find out how Mauritius can be promoted as a holiday destination in Finland. This study was conducted via an analysis of the tourism business environment and interviews. The analytical tools used were a SWOT analysis and Porter’s five ...

  7. Some viewpoints on reference biospheres in Finnish performance assessments

    International Nuclear Information System (INIS)

    Rasilainen, K.; Kattilakoski, E.; Suolanen, V.; Vieno, T.; Vuori, S.

    2002-01-01

    Viewpoints are presented concerning biosphere studies in performance assessments of nuclear waste disposal. The points are based on experiences from several Finnish performance assessments. The latest performance assessment for spent fuel disposal, TILA-99, was considered in the Decision in Principle process for the site selection of the repository. The points given are also based on experiences from participation in international projects dealing with biosphere modelling, for instance BIOMOVS and BIOMASS. (author)

  8. Mapping of fertility traits in Finnish Ayrshire by genome-wide association analysis

    DEFF Research Database (Denmark)

    Schulmann, Nina F; Sahana, Goutam; Iso-Touru, T

    2011-01-01

    A whole-genome scan using single marker association was used to detect chromosome regions associated with seven female fertility traits in Finnish Ayrshire dairy cattle. The phenotypic data consisted of de-regressed estimated breeding values for 340 bulls which were estimated using a single trait...

  9. Hereditary nonpolyposis colorectal cancer and familial colorectal cancer in Central part of Iran, Isfahan

    Directory of Open Access Journals (Sweden)

    Amin Nemati

    2012-01-01

    Full Text Available Background: There is a lack of data on familial aggregation of colorectal cancer (CRC in Iran. We aimed to deter-mine the frequency of hereditary nonpolyposis colorectal cancer (HNPCC and familial colorectal cancer (FCC and to determine the frequency of extracolonic cancers in these families in Isfahan. Methods: We reviewed documents of all patients with a pathologically confirmed diagnosis of CRC admitted to Isfa-han referral hospitals between 1995 and 2006. We also studied our CRC registry at Poursina Hakim Research Institute from 2003 to 2008. We found HNPCC and FCC families based on the Amsterdam II criteria and interviewed them for family history of CRC and extracolonic tumors. The family history was taken at least up to the second-degree relatives. Results: During 1996 to 2008, a total of 2580 CRC cases have been diagnosed. We found 14 HNPCC and 53 FCC families. Mean age of CRC at diagnosis was 48.0 ΁ 14.6 and 49.0 ΁ 13.9 years in the HNPCC and FCC families, re-spectively (p > 0.05. The total numbers of observed extracolonic tumors were 70 (21.6%; mean age = 53.6 ΁ 11.0 years and 157 (13.8%; mean age = 54.8 ΁ 18.0 years in HNPCC and FCC families, respectively (p > 0.05. CRC was respectively found in 52 and 76 members of the HNPCC and FCC families, revealing the frequency of HNPCC and FCC as 2.0% (52/2580 and 2.9% (76/2580, respectively. Conclusions: We found a relative high frequency of HNPCC (2.0% and FCC (2.9% among CRC cases in our socie-ty and high incidence of extracolonic tumors in their families. Further studies focusing on molecular basis in this field and designing a specific screening and national cancer registry program for HNPCC and FCC families should be con-ducted.

  10. Leadership styles of Finnish nurse managers and factors influencing it.

    Science.gov (United States)

    Vesterinen, Soili; Isola, Arja; Paasivaara, Leena

    2009-05-01

    The purpose of the present study was to explore nurse managers' perceptions of their leadership styles and factors influencing it. It is a challenge for nurse managers to retain nurses in hospitals and to ensure a high quality of care in nursing practice. Leadership style is an important part of leadership. Knowledge concerning nurse managers' resonant and non-resonant leadership styles provides nurse managers with tools to reflect on their own leadership style. Open-ended, tape-recorded interviews were conducted with 13 nurse managers from five Finnish hospitals and two long-term care facilities. The data were analysed using qualitative content analysis. Five categories of leadership style were discerned: visionary, coaching, affiliate, democratic, commanding. Factors that influence leadership style were identified: earlier superiors, values, information, cooperation, employees and education. The results of this study show that Finnish nurse managers use both resonant and non-resonant leadership styles. The findings of this study show that nurse managers use a variety of leadership styles. The study demonstrates the importance of knowledge about leadership styles and factors influencing it among nurse managers providing future leadership and management education.

  11. Moyamoya vasculopathy - Patient demographics and characteristics in the Finnish population.

    Science.gov (United States)

    Saarela, Marika; Mustanoja, Satu; Pekkola, Johanna; Tyni, Tiina; Hernesniemi, Juha; Kivipelto, Leena; Tatlisumak, Turgut

    2017-01-01

    Background and purpose Moyamoya vasculopathy, a rare steno-occlusive progressive cerebrovascular disorder, has not been thoroughly studied in Caucasian populations. We established a registry of Finnish patients treated at the Helsinki University Hospital, to collect and report demographic and clinical data. Methods We collected data both retrospectively and prospectively from all the patients with a moyamoya vasculopathy referred to our hospital between January 1987 and December 2014. All patients underwent a neurological outpatient clinic visit. Results We diagnosed 61 patients (50 females, 10 children) with moyamoya vasculopathy. The mean age at the disease-onset was 31.5 ± 17.9 years. The two most common presenting symptoms were ischemic stroke (n = 31) and hemorrhage (n = 8). Forty-four percent underwent revascularization surgery, and 70% were prescribed antithrombotic treatment. Conclusions The results support in part the Western phenotype of the disease considering the later presentation and larger female predominance compared to the Asian moyamoya vasculopathy reports. However, the proportion of ischemic strokes and hemorrhagic strokes is closer to Japanese population than German population. The absence of familial cases points to a different genetic profile in the Finnish patients.

  12. Germ line mutations of mismatch repair genes in hereditary nonpolyposis colorectal cancer patients with small bowel cancer: International Society for Gastrointestinal Hereditary Tumours Collaborative Study

    DEFF Research Database (Denmark)

    Park, Jae-Gahb; Kim, Duck-Woo; Hong, Chang Won

    2006-01-01

    PURPOSE: The aim of study was to determine the clinical characteristics and mutational profiles of the mismatch repair genes in hereditary nonpolyposis colorectal cancer (HNPCC) patients with small bowel cancer (SBC). EXPERIMENTAL DESIGN: A questionnaire was mailed to 55 members of the Internatio......PURPOSE: The aim of study was to determine the clinical characteristics and mutational profiles of the mismatch repair genes in hereditary nonpolyposis colorectal cancer (HNPCC) patients with small bowel cancer (SBC). EXPERIMENTAL DESIGN: A questionnaire was mailed to 55 members...... of the International Society for Gastrointestinal Hereditary Tumours, requesting information regarding patients with HNPCC-associated SBC and germ line mismatch repair gene mutations. RESULTS: The study population consisted of 85 HNPCC patients with identified mismatch repair gene mutations and SBCs. SBC was the first...... HNPCC-associated malignancy in 14 of 41 (34.1%) patients for whom a personal history of HNPCC-associated cancers was available. The study population harbored 69 different germ line mismatch repair gene mutations, including 31 mutations in MLH1, 34 in MSH2, 3 in MSH6, and 1 in PMS2. We compared...

  13. Localization of A Novel Autosomal Recessive Non-Syndromic Hearing Impairment Locus (DFNB38) to 6q26–q27 in a Consanguineous Kindred from Pakistan

    Science.gov (United States)

    Ansar, Muhammad; Ramzan, Mohammad; Pham, Thanh L.; Yan, Kai; Jamal, Syed Muhammad; Haque, Sayedul; Ahmad, Wasim; Leal, Suzanne M.

    2010-01-01

    For autosomal recessive nonsyndromic hearing impairment over 30 loci have been mapped and 19 genes have been identified. DFNB38, a novel locus for autosomal recessive nonsyndromic hearing impairment, was localized in a consanguineous Pakistani kindred to 6q26–q27. The affected family members present with profound prelingual sensorineural hearing impairment and use sign language for communications. Linkage was established to microsatellite markers located on chromosome 6q26–q27 (Multipoint lod score 3.6). The genetic region for DFNB38 spans 10.1 cM according to the Marshfield genetic map and is bounded by markers D6S980 and D6S1719. This genetic region corresponds to 3.4 MB on the sequence-based physical map. PMID:12890929

  14. Energy security impacts of a severe drought on the future Finnish energy system.

    Science.gov (United States)

    Jääskeläinen, Jaakko; Veijalainen, Noora; Syri, Sanna; Marttunen, Mika; Zakeri, Behnam

    2018-07-01

    Finland updated its Energy and Climate Strategy in late 2016 with the aim of increasing the share of renewable energy sources, increasing energy self-sufficiency and reducing greenhouse gas emissions. Concurrently, the issue of generation adequacy has grown more topical, especially since the record-high demand peak in Finland in January 2016. This paper analyses the Finnish energy system in years 2020 and 2030 by using the EnergyPLAN simulation tool to model whether different energy policy scenarios result in a plausible generation inadequacy. Moreover, as the Nordic energy system is so heavily dependent on hydropower production, we model and analyse the impacts of a severe drought on the Finnish energy system. We simulate hydropower availability according to the weather of the worst drought of the last century (in 1939-1942) with Finnish Environment Institute's Watershed Simulation and Forecasting System and we analyse the indirect impacts via reduced availability of electricity imports based on recent realised dry periods. Moreover, we analyse the environmental impacts of hydropower production during the drought and peak demand period and the impacts of climate change on generation adequacy in Finland. The results show that the scenarios of the new Energy and Climate Strategy result in an improved generation adequacy comparing to the current situation. However, a severe drought similar to that experienced in 1940s could cause a serious energy security threat. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. How magnetic are Finnish hospitals measured by transformational leadership and empirical quality outcomes?

    Science.gov (United States)

    Kvist, Tarja; Mäntynen, Raija; Turunen, Hannele; Partanen, Pirjo; Miettinen, Merja; Wolf, Gail A; Vehviläinen-Julkunen, Katri

    2013-01-01

      The overall aim of this study was to examine nurses' and patients' perceptions of the Magnet model components of transformational leadership and empirical quality outcomes in four Finnish hospitals and to determine if the evidence for transformational leadership and empirical quality outcomes is the same or different in the four hospitals.   This report presents baseline measurements for a longitudinal study of the adaptation of the Magnet model in Finnish hospitals.   Web-based surveys and mailed questionnaires were used in 2008-2009 to collect data from patients (n = 2566) about their satisfaction with care, and from nursing staff about transformational leadership (n = 1151), job satisfaction (n = 2707) and patient safety culture (n = 925) in the selected hospitals.   Awareness of the work of nursing leaders was low. Nurses reported a high level of job satisfaction. Patient safety culture varied considerably between the four hospitals. Patients believed they generally received excellent quality care.   Leadership systems are in transition at the hospitals. Patient safety culture is a complex phenomenon that may be unfamiliar to respondents. The results of the study provide a baseline description to guide the journey toward development of Magnet standards.   Finnish nursing leaders, especially nursing directors, should increase their visibility by working more closely with their staff. They should also pay attention to giving direct feedback about work generally and patient safety issues in particular. © 2012 Blackwell Publishing Ltd.

  16. Geography in the Finnish School Curriculum: Part of the "Success Story"?

    Science.gov (United States)

    Tani, Sirpa

    2014-01-01

    The article investigates the status of geography education in the Finnish national curricula from the 1970s until today. Conceptions of teaching, learning and change in society are traced through curriculum texts; in addition, the ways in which these are applied in the subject-specified aims and content of the geography curriculum are explored.…

  17. A missense mutation in ALDH1A3 causes isolated microphthalmia/anophthalmia in nine individuals from an inbred Muslim kindred.

    Science.gov (United States)

    Mory, Adi; Ruiz, Francesc X; Dagan, Efrat; Yakovtseva, Evgenia A; Kurolap, Alina; Parés, Xavier; Farrés, Jaume; Gershoni-Baruch, Ruth

    2014-03-01

    Nine affected individuals with isolated anophthalmia/microphthalmia from a large Muslim-inbred kindred were investigated. Assuming autosomal-recessive mode of inheritance, whole-genome linkage analysis, on DNA samples from four affected individuals, was undertaken. Homozygosity mapping techniques were employed and a 1.5-Mbp region, homozygous in all affected individuals, was delineated. The region contained nine genes, one of which, aldehyde dehydrogenase 1 (ALDH1A3), was a clear candidate. This gene seems to encode a key enzyme in the formation of a retinoic-acid gradient along the dorsoventral axis during an early eye development and the development of the olfactory system. Sanger sequence analysis revealed a missense mutation, causing a substitution of valine (Val) to methionine (Met) at position 71. Analyzing the p.Val71Met missense mutation using standard open access software (MutationTaster online, PolyPhen, SIFT/PROVEAN) predicts this variant to be damaging. Enzymatic activity, studied in vitro, showed no changes between the mutated and the wild-type ALDH1A3 protein.

  18. Examining gambling-related crime reports in the National Finnish Police Register.

    Science.gov (United States)

    Kuoppamäki, Sanna-Mari; Kääriäinen, Juha; Lind, Kalle

    2014-12-01

    The aim of this study is to examine the connection between gambling and criminal activity in the National Finnish Police Register. First, a method was created that enabled the search for gambling-related police reports in the National Finnish Police Register. The method is based on finding gambling-related police reports by using gambling-related headwords. Second, all police reports from 2011 that included any mention of gambling were read through (n = 2,233). Suspected gambling-related of crimes (n = 737) were selected from these reports. Those suspected gambling-related crimes were then described and categorized into six different categories: suspected online-related crimes; suspected crimes that were related to lifestyle-gaming; suspected crimes that involved a gambler as a victim of a crime; criminal activity related to problem gambling; casino-connected crimes, and intimate partnership violence resulting from gambling problems. This study, being the first in Finland, generated information on the connection between gambling and criminal activity from the perspective of police reports. Moreover, the study highlights methodological issues that are involved in studying police reports.

  19. Are Foreign Investments Replacing Domestic Investments? - Evidence from Finnish Manufacturing

    OpenAIRE

    Oksanen, Olli-Pekka

    2006-01-01

    This study analyses the relationship between firms’ foreign and domestic investments using a panel dataset containing 218 Finnish manufacturing firms during the years 1998-2002. The study examines whether foreign investments increase or decrease domestic investments and whether the effect varies between investments directed to developed markets or emerging markets. Financial constraints’ effect on the relationship is also investigated. The empirical part estimates an empirical investment equa...

  20. Explaining technical change in a small country the Finnish national innovation system

    CERN Document Server

    Vuorinen, Pentti

    1994-01-01

    Technical change is produced by the interaction of a large number of technical, economic, social and institutional factors. One of the starting points is the concept of national innovation systems. The aim of this book is to take Finland as an example illustrating the challenges faced by small countries. The characteristics and performance of the Finnish national innovation system of the last couple of decades are analyzed. The Finnish experience is put in a broader context by comparing it with a few other countries. The development paths possible in the near future are assessed. According to the results, many problems remain despite favourable developments in several technology indicators. The rigidities of the social institutions created during the 1970s and 1980s seem to have become obstacles for economic and technological development. There are fairly large differences between the countries studied, and even between the culturally and historically close Nordic countries. However,Finland and Sweden seem to...

  1. Finnish energy technologies for the future

    International Nuclear Information System (INIS)

    2007-01-01

    The global energy sector is going through major changes: the need for energy is growing explosively, while at the same time climate change is forcing US to find new, and cleaner, ways to generate energy. Finland is one of the forerunners in energy technology development, partly because of its northern location and partly thanks to efficient innovations. A network of centres of expertise was established in Finland in 1994 to boost the competitiveness and internationalisation of Finnish industry and, consequently, that of the EU region. During the expertise centre programme period 2007-2013, substantial resources will be allocated to efficient utilisation of top level expertise in thirteen selected clusters of expertise. The energy cluster, focusing on developing energy technologies for the future, is one of these

  2. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1992-05-01

    The Finnish nuclear power plant units Loviisa 1 and 2 as well as TVO I and II were in operation for almost the whole fourth quarter of 1991. The load factor average was 94.7 % (the whole year 90.9 %). All the events in the last annual quarter, which are classified on the International Nuclear Event Scale, were below scale/level 0. Also the events which occurred in the other quarters of the year 1991 were rated at the scale's lowest levels. Occupational radiation doses and releases of radioactive material off-site remained well below authorised limits. Only quantities of radioactive material insignificant to radiation exposure originating in nuclear power plants were detected in the samples collected in the vicinity of the nuclear power plants

  3. IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease

    Directory of Open Access Journals (Sweden)

    Vatta Serena

    2009-01-01

    Full Text Available Abstract Background Association of the interleukin-23 receptor (IL23R with inflammatory bowel disease (IBD has been confirmed in several populations. IL23R also associates with psoriasis, suggesting that the gene may be an important candidate for many chronic inflammatory diseases. Methods We studied association of single-nucleotide variants in IL23R with IBD in Swedish patients, in both Crohn's disease (CD and ulcerative colitis (UC subsets. The same genetic variants were also studied in Finnish patients with psoriasis or celiac disease, and in Hungarian and Italian patients with celiac disease. Results Association of IL23R with IBD was replicated in our Swedish patients, and linkage and association of the IL23R region with psoriasis was found in the Finnish population. The IL23R region was also linked to celiac disease in Finnish families, but no association of IL23R variants with celiac disease was found in the Finnish, Hungarian or Italian samples. Conclusion Our study is the first to demonstrate association of IL23R with CD and UC in Swedish patients with IBD. It is also the first study to report linkage and association of the IL23R region with psoriasis in the Finnish population. Importantly, this is the first report of linkage of the IL23R region to celiac disease, a chronic inflammatory condition in which IL23R has not been previously implicated.

  4. Cleanup techniques for Finnish urban environments and external doses from 137Cs - modelling and calculations

    International Nuclear Information System (INIS)

    Moring, M.; Markkula, M.L.

    1997-03-01

    The external doses under various radioactive deposition conditions are assessed and the efficiencies of some simple decontamination techniques (grass cutting, vacuum sweeping, hosing of paved surfaces and roofs, and felling trees) are compared in the study. The present model has been constructed for the Finnish conditions and housing areas, using 137 Cs transfer data from the Nordic and Central European studies and models. The compartment model concerns behaviour and decontamination of 137 Cs in the urban environment under summer conditions. Doses to man have been calculated for wet (light rain) and dry deposition in four typical Finnish building areas: single-family wooden houses, brick terraced-houses, blocks of flats and urban office buildings. (26 refs.)

  5. Examining the Differences of Linear Systems between Finnish and Taiwanese Textbooks

    Science.gov (United States)

    Yang, Der-Ching; Lin, Yung-Chi

    2015-01-01

    The purpose of this study was to examine the differences between Finnish and Taiwanese textbooks for grades 7 to 9 on the topic of solving systems of linear equations (simultaneous equations). The specific textbooks examined were TK in Taiwan and FL in Finland. The content analysis method was used to examine (a) the teaching sequence, (b)…

  6. Operating experiences at the Finnish TRIGA reactor

    International Nuclear Information System (INIS)

    Salmenhaara, Seppo

    1988-01-01

    The Finnish TRIGA reactor has been in operation since March 1962. There are still 57 original Al-clad fuel elements in the core. So far we have had only two fuel cladding failures in 1981 and 1988. The first one was an Al-clad element and the second one a SS-clad. The low rate of fuel cladding failures has made it possible to use continuously also the Al-clad fuel elements. Although some conventional irradiations of certain type have been repeated successfully tens of times, new and unexpected incidents can still take place. As an example an event of a leaking irradiation capsule is described

  7. Secular Ethics Education as an Alternative to Religious Education--Finnish Teachers' Views

    Science.gov (United States)

    Zilliacus, Harriet; Kallioniemi, Arto

    2016-01-01

    This study provides a Finnish perspective to international discussions on religious and worldviews education through the subject of secular ethics. This subject has been offered in Finland since 1985 throughout comprehensive schools and is primarily directed at students who are non-affiliated. Secular ethics education has scarcely been researched…

  8. Happy Spouses, Happy Parents? Family Relationships among Finnish and Dutch Dual Earners

    Science.gov (United States)

    Malinen, Kaisa; Kinnunen, Ulla; Tolvanen, Asko; Ronka, Anna; Wierda-Boer, Hilde; Gerris, Jan

    2010-01-01

    In this study links between spousal and parent-child relationships among Finnish (n = 157 couples) and Dutch (n = 276 couples) dual earners with young children were examined using paired questionnaire data. Variable-oriented analyses (structural equation modeling with a multigroup procedure) supported the spillover hypothesis, as higher levels of…

  9. Operation of Finnish nuclear power plants. Quarterly report, 2nd quarter 1999

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1999-12-01

    Quarterly reports on the operation of Finnish NPPs describe events and observations relating to nuclear and radiation safety that the Finnish Radiation and Nuclear Safety Authority (STUK) considers safety significant. Safety improvements at the plants are also described. The report includes a summary of the radiation safety of plant personnel and the environment and tabulated data on the plants' production and load factors. All Finnish NPP units were in power operation for the whole second quarter of 1999, with the exception of the annual maintenance outages of the Olkiluoto plant units. The load factor average of the plant units in this quarter was 93.1%. Two events in this quarter were classified Level 1 on the INKS Scale. At Olkiluoto 1, a valve of the containment gas treatment system had been in an incorrect position for almost a month, owing to which the system would not have been available as planned in an accident. At Olkiluoto 2, main circulation pump work was done during the annual maintenance outage and a containment personnel air lock was briefly open in violation of the Technical Specifications. Water leaking out of the reactor in an accident could not have been directed to the emergency cooling system because it would have leaked out from the containment via the open personnel air lock. Other events in this quarter had no bearing on the nuclear or radiation safety of the plant units. The individual doses of NPP personnel and also radioactive releases off-site were well below authorised limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.)

  10. Investigating the cross-cultural validity of DSM-5 autism spectrum disorder: evidence from Finnish and UK samples.

    Science.gov (United States)

    Mandy, William; Charman, Tony; Puura, Kaija; Skuse, David

    2014-01-01

    The recent Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) reformulation of autism spectrum disorder has received empirical support from North American and UK samples. Autism spectrum disorder is an increasingly global diagnosis, and research is needed to discover how well it generalises beyond North America and the United Kingdom. We tested the applicability of the DSM-5 model to a sample of Finnish young people with autism spectrum disorder (n = 130) or the broader autism phenotype (n = 110). Confirmatory factor analysis tested the DSM-5 model in Finland and compared the fit of this model between Finnish and UK participants (autism spectrum disorder, n = 488; broader autism phenotype, n = 220). In both countries, autistic symptoms were measured using the Developmental, Diagnostic and Dimensional Interview. Replicating findings from English-speaking samples, the DSM-5 model fitted well in Finnish autism spectrum disorder participants, outperforming a Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) model. The DSM-5 model fitted equally well in Finnish and UK autism spectrum disorder samples. Among broader autism phenotype participants, this model fitted well in the United Kingdom but poorly in Finland, suggesting that cross-cultural variability may be greatest for milder autistic characteristics. We encourage researchers with data from other cultures to emulate our methodological approach, to map any cultural variability in the manifestation of autism spectrum disorder and the broader autism phenotype. This would be especially valuable given the ongoing revision of the International Classification of Diseases-11th Edition, the most global of the diagnostic manuals.

  11. Epidemiology of Anorexia Nervosa in Men : A Nationwide Study of Finnish Twins

    NARCIS (Netherlands)

    Raevuori, Anu; Hoek, Hans W.; Susser, Ezra; Kaprio, Jaakko; Rissanen, Aila; Keski-Rahkonen, Anna

    2009-01-01

    Background: To examine the epidemiology of anorexia nervosa in men, we screened Finnish male twins born in 1975-79. Methods and Findings: Men (N = 2122) from FinnTwin16 birth cohorts were screened for lifetime eating disorders by a questionnaire. The screen positives (N = 18), their male co-twins (N

  12. School-External Factors in Finnish Content and Language Integrated Learning (CLIL) Programs

    Science.gov (United States)

    Aro, Sophie; Mikkilä-Erdmann, Mirjamaija

    2015-01-01

    This study investigated the relationship between the English language competence of Finnish bilingual pupils and school-external factors such as parental expectations, home involvement, and exposure to English outside the classroom. Data on the pupils' language competence was collected from n?=?122 6th graders in bilingual education, and compared…

  13. The Implementation of Entrepreneurship Education through Curriculum Reform in Finnish Comprehensive Schools

    Science.gov (United States)

    Seikkula-Leino, Jaana

    2011-01-01

    How has entrepreneurship education been implemented in Finnish comprehensive schools. A two-part survey was undertaken in 43 municipalities with different educational and socio-economic backgrounds. The first part, in 2005, dealt with the local curriculum reform with a focus on the development of entrepreneurship education. The second part, in…

  14. Enacting the Common Script: Management Ideas at Finnish Universities of Applied Sciences

    Science.gov (United States)

    Vuori, Johanna

    2015-01-01

    This article discusses the work of mid-level management at Finnish universities of applied sciences. Based on in-depth interviews with 15 line managers, this study investigates how the standardized management ideas of rational management and employee empowerment are used in the leadership of lecturers at these institutions. The findings indicate…

  15. Differences in Sickness Allowance Receipt between Swedish Speakers and Finnish Speakers in Finland

    Directory of Open Access Journals (Sweden)

    Kaarina S. Reini

    2017-12-01

    Full Text Available Previous research has documented lower disability retirement and mortality rates of Swedish speakers as compared with Finnish speakers in Finland. This paper is the first to compare the two language groups with regard to the receipt of sickness allowance, which is an objective health measure that reflects a less severe poor health condition. Register-based data covering the years 1988-2011 are used. We estimate logistic regression models with generalized estimating equations to account for repeated observations at the individual level. We find that Swedish-speaking men have approximately 30 percent lower odds of receiving sickness allowance than Finnish-speaking men, whereas the difference in women is about 15 percent. In correspondence with previous research on all-cause mortality at working ages, we find no language-group difference in sickness allowance receipt in the socially most successful subgroup of the population.

  16. HOLIDAY FROM HELL : Bad travel experiences of Finnish people

    OpenAIRE

    Miettinen, Milja

    2015-01-01

    The topic of this thesis was the bad travel experiences of Finnish people. This thesis is divided into two parts. The theoretical framework consists of Maslow’s hierarchy of needs, tourism consumer behaviour, experience and experience economy. In the empirical part, a survey was used and answers were collected by a questionnaire on the Internet. The link to the questionnaire was published in Facebook and also on Suomi24 forum’s travel section. It was possible to answer to the questionnai...

  17. Oral health-related self-efficacy beliefs and toothbrushing: Finnish and Turkish pre-adolescents' and their mothers' responses

    DEFF Research Database (Denmark)

    Cinar, Ayse Basak; Tseveenjav, Battsetseg; Murtomaa, Heikki

    2009-01-01

    The aim of this study was to investigate the association between cognitive and behavioural factors of preadolescents and those of their mothers, assessed in terms of self-efficacy beliefs and toothbrushing among Turkish and Finnish population in the framework of Social Cognitive Theory. The speci....... The specific objective was to test if this possible association worked regardless of cultural differences.......The aim of this study was to investigate the association between cognitive and behavioural factors of preadolescents and those of their mothers, assessed in terms of self-efficacy beliefs and toothbrushing among Turkish and Finnish population in the framework of Social Cognitive Theory...

  18. Overcoming Barriers to Frugal Innovation: Emerging Opportunities for Finnish SMEs in Brazilian Markets

    Directory of Open Access Journals (Sweden)

    Mirva Hyypiä

    2018-04-01

    Full Text Available Frugal innovation has become a popular concept, in academia but also in industry at large. Although there has been a great deal of discussion about the relevance of frugal innovation to the developed world, the notion’s full acceptance within small and medium-sized enterprises (SMEs still seems far in the distance. The opportunities and barriers seen with practical implementation of frugal innovation during the development processes have received little attention. This article considers these opportunities and barriers in the context of Finnish SMEs, providing insight specifically into the approaches these companies take in Brazilian markets. Qualitative data were drawn from a case study forming part of an extensive action research-based development project called SCALA, aimed at creating suitable and scalable mobile learning services for global markets. The concepts of frugal innovation and proceeding from user needs – essential parts of the development processes – are examined by observing three Finnish SMEs and their top managers, with particular focus on their interaction with Brazilian partners. Development sessions and meetings shed light on how the companies perceived and responded to testing their products/services with six individual schools in Brazil. Although frugal innovation is seen as essential for guaranteeing long-term competitiveness of Finnish SMEs – and access to rapidly growing, unsaturated emerging markets such as Brazil can be a step in the right direction – our study highlights numerous barriers and ways to overcome them in the real-world implementation of frugality in SMEs’ development processes.

  19. Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer

    Science.gov (United States)

    Carethers, John M; Stoffel, Elena M

    2015-01-01

    Hereditary non-polyposis colorectal cancer (HNPCC) was previously synonymous with Lynch syndrome; however, identification of the role of germline mutations in the DNA mismatch repair (MMR) genes has made it possible to differentiate Lynch syndrome from other conditions associated with familial colorectal cancer (CRC). Broadly, HNPCC may be dichotomized into conditions that demonstrate defective DNA MMR and microsatellite instability (MSI) vs those conditions that demonstrate intact DNA MMR. Conditions characterized by MMR deficient CRCs include Lynch syndrome (germline MMR mutation), Lynch-like syndrome (biallelic somatic MMR mutations), constitutional MMR deficiency syndrome (biallelic germline MMR mutations), and sporadic MSI CRC (somatic biallelic methylation of MLH1). HNPCC conditions with intact DNA MMR associated with familial CRC include polymerase proofreading associated polyposis and familial colorectal cancer type X. Although next generation sequencing technologies have elucidated the genetic cause for some HNPCC conditions, others remain genetically undefined. Differentiating between Lynch syndrome and the other HNPCC disorders has profound implications for cancer risk assessment and surveillance of affected patients and their at-risk relatives. Clinical suspicion coupled with molecular tumor analysis and testing for germline mutations can help differentiate the clinical mimicry within HNPCC and facilitate diagnosis and management. PMID:26309352

  20. Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer.

    Science.gov (United States)

    Carethers, John M; Stoffel, Elena M

    2015-08-21

    Hereditary non-polyposis colorectal cancer (HNPCC) was previously synonymous with Lynch syndrome; however, identification of the role of germline mutations in the DNA mismatch repair (MMR) genes has made it possible to differentiate Lynch syndrome from other conditions associated with familial colorectal cancer (CRC). Broadly, HNPCC may be dichotomized into conditions that demonstrate defective DNA MMR and microsatellite instability (MSI) vs those conditions that demonstrate intact DNA MMR. Conditions characterized by MMR deficient CRCs include Lynch syndrome (germline MMR mutation), Lynch-like syndrome (biallelic somatic MMR mutations), constitutional MMR deficiency syndrome (biallelic germline MMR mutations), and sporadic MSI CRC (somatic biallelic methylation of MLH1). HNPCC conditions with intact DNA MMR associated with familial CRC include polymerase proofreading associated polyposis and familial colorectal cancer type X. Although next generation sequencing technologies have elucidated the genetic cause for some HNPCC conditions, others remain genetically undefined. Differentiating between Lynch syndrome and the other HNPCC disorders has profound implications for cancer risk assessment and surveillance of affected patients and their at-risk relatives. Clinical suspicion coupled with molecular tumor analysis and testing for germline mutations can help differentiate the clinical mimicry within HNPCC and facilitate diagnosis and management.

  1. “The Terrible Visitation”: Famine in Finland and Ireland 1845-68 - Towards An Agenda for Comparative Irish-Finnish Famine Studies

    DEFF Research Database (Denmark)

    Newby, Andrew; Myllyntaus, Timo

    2015-01-01

    national history, and has had a considerable impact on Irish identity. Since the 150th anniversary of the Great Famine in the late 1990s, prodigious amounts of academic and popular literature have been published on the subject. From an Irish perspective, the historiography of the Great Finnish Famine......, which culminated in 1868, seems somewhat limited. Cormac Ó Gráda, one of the most renowned Irish economic historians, has described the Finnish catastrophe as the “last great subsistence crisis of the western world,” but has also complained that it remains “unduly neglected,” and stressed the potential...... for comparative studies with Ireland. This period of Finnish history tends to be presented as a period of general economic malaise, associated with national “growing pains” as Finland sought to establish itself as an autonomous country....

  2. Metal and engineering industry in the Finnish economy

    International Nuclear Information System (INIS)

    Maeenpaeae, I.; Viitanen, M.; Juutinen, A.

    1996-01-01

    The study analyses quantitatively the position, internal structures and environmental aspects of the metal sector (basic metal industry, mechanical engineering, electronics and electrotechnics) in the recent past of the Finnish economy. The changes in the sector by the year 2005 are assessed by means of a macroeconomic simulation model as well. The future development of the metal sector by the year 2005 was assessed by the FMS model system, for which a detailed metal sector sub-model was constructed. The scenario of the general development of the Finnish economy was tuned so that it corresponds as closely as possible to the recent basic projections of the economy made by the government authorities. Three scenarios for the metal sector were constructed: base scenario, rapid and slow growth scenarios. In the base scenario the production volume of the metal sector grows by 6 per cent annually between 1994-2005 while the annual growth rate of the whole industry is 4 per cent and that of the GDP 3 per cent. In the rapid growth scenario, the growth rate of the metal sector goes up to 10 per cent and in the slow growth scenario down to 3 per cent. In the assessment of environmental effects of the metal sector are included energy consumption, emissions into the air, use on natural resources, waste formation and recycling of metals. Although the production volume of the metal sector almost doubles between 1990 - 2000, the consumption of primary energy grows only about one fourth and that of the electricity by 50 per cent

  3. Finnish version of the Tampa Scale of Kinesiophobia: Reference values in the Finnish general population and associations with leisure-time physical activity.

    Science.gov (United States)

    Koho, Petteri; Borodulin, Katja; Kautiainen, Hannu; Kujala, Urho; Pohjolainen, Timo; Hurri, Heikki

    2015-03-01

    To create reference values for the general Finnish population using the Tampa Scale of Kinesiophobia (TSK-FIN), to study gender differences in the TSK-FIN, to assess the internal consistency of the TSK-FIN, to estimate the prevalence of high levels of kinesiophobia in Finnish men and women, and to examine the association between kinesiophobia and leisure-time physical activity and the impact of co-morbidities on kinesiophobia. The study population comprised 455 men and 579 women. Participants completed a self-administered questionnaire about their socio-demographic factors, leisure-time physical activity, co-morbidities and kinesiophobia. The mean TSK-FIN score was significantly higher for men (mean 34.2, standard deviation (SD) 6.9) compared with women (mean 32.9, SD 6.5), with an age-adjusted p = 0.004 for the difference between men and women. Cronbach's alpha was 0.72, indicating substantial internal consistency. Men over 55 years of age and women over 65 years of age had a higher (p physical activity among both sexes. The presence of cardiovascular disease, musculoskeletal disease or a mental disorder was associated with a higher TSK-FIN score compared with the absence of the aforementioned disorders. We present here the reference values for the TSK-FIN. The reference values and prevalence among the general population may help clinicians to define the level of kinesiophobia among patients. Disorders other than musculoskeletal diseases were associated with kinesiophobia, which should be noted in daily practice.

  4. Regional Growth and Unemployment: The Validity of Okun's Law for the Finnish Regions

    NARCIS (Netherlands)

    Kangasharju, A.; Tavera, C.; Nijkamp, P.

    2012-01-01

    This paper offers a concise critical overview of Okun's Law, with particular attention for its relevance in open economic systems of regions. Based on an extensive set of economic data for Finnish regions, the existence of cointegration is tested using alternative statistical methods, viz. the

  5. Reference values of spirometry for Finnish adults.

    Science.gov (United States)

    Kainu, A; Timonen, K L; Toikka, J; Qaiser, B; Pitkäniemi, J; Kotaniemi, J T; Lindqvist, A; Vanninen, E; Länsimies, E; Sovijärvi, A R A

    2016-09-01

    Diagnostic assessment of lung function necessitates up-to-date reference values. The aim of this study was to estimate reference values for spirometry for the Finnish population between 18 and 80 years and to compare them with the existing Finnish, European and the recently published global GLI2012 reference values. Spirometry was performed for 1380 adults in the population-based FinEsS studies and for 662 healthy non-smoking volunteer adults. Detailed predefined questionnaire screening of diseases and symptoms, and quality control of spirometry yielded a sample of 1000 native Finns (387 men) healthy non-smokers aged 18-83 years. Sex-specific reference values, which are estimated using the GAMLSS method and adjusted for age and height, are provided. The predicted values for lung volumes are larger than those obtained by GLI2012 prediction for the Caucasian subgroup for forced vital capacity (FVC) by an average 6·2% and 5·1% and forced expiratory volume in 1 s (FEV1) by an average 4·2% and 3·0% in men and women, respectively. GLI2012 slightly overestimated the ratio FEV1/FVC with an age-dependent trend. Most reference equations from other European countries, with the exception of the Swiss SAPALDIA study, showed an underestimation of FVC and FEV1 to varying degrees, and a slight overestimation of FEV1/FVC. This study offers up-to-date reference values of spirometry for native Finns with a wide age range. The GLI2012 predictions seem not to be suitable for clinical use for native Finns due to underestimation of lung volumes. © 2015 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.

  6. Principals' Perceptions for Finnish- and Swedish-Language Schools in Finland: An Analysis of School-Level Indices from Programme for International Student Assessment 2009

    Science.gov (United States)

    Harju-Luukkainen, Heidi; Vettenranta, Jouni; Kanervio, Pekka; Pulkkinen, Seppo

    2014-01-01

    The Finnish educational system is known for its equality. However, in many key areas in national and international assessments, Swedish-language schools in Finland have lagged behind their Finnish-language counterparts. So far there is little research into the underlying reasons for this discrepancy. In this article, in order to illuminate the…

  7. Somatic mosaicism and female-to-female transmission in a kindred with hemophilia B (factor IX deficiency)

    International Nuclear Information System (INIS)

    Taylor, S.A.M.; Deugau, K.V.; Lillicrap, D.P.

    1991-01-01

    Studies have shown that hemophilia B (Christmas disease; factor IX deficiency) results from many different mutations in the factor IX gene, of which >95% are single nulceotide substitutions. This study has identified a previously unreported form of hemophilia B in a patient who was a somatic mosaic for a guanine-to-cytosine transversion at nucleotide 31,170 in the factor IX gene. This point mutation changes the codon for residue 350 in the catalytic domain of factor IX from a cysteine to a serine. The authors used differential termination of primer extension to confirm and measure the degree of mosaicism. The study shows that a varying proportion of cells from hepatic, renal, smooth muscle, and hematopoietic populations possessed normal as well as mutant factor IX sequences. These results indicate that the mutation in this patient occurred either as an uncorrected half-chromatid mutation in the female gamete or as a replication or postreplication error in the initial mitotic divisions of the zygote preceding implantation. In addition, this kindred also contains two females in successive generations who have moderately severe factor IX deficiency. The molecular pathogenesis of this latter phenomenon has been studied and seems to relate to the unaccompanied expression of the mutant factor IX gene consequent upon a second, as yet undefined, genetic event that has prevented inactivation of sequences including the mutant factor IX gene on the X chromosome inherited from the affected male

  8. Content of copper, zinc, lead, cadmium and mercury in muscle, liver and kidney of Finnish cattle

    Energy Technology Data Exchange (ETDEWEB)

    Stabel-Taucher, R; Nurmi, E; Karppanen, E

    1975-01-01

    A total of 120 normal slaughter cows were analyzed with respect to Cu, Zn, Pb, Cd and Hg in muscle, liver and kidneys. The cows originated from 6 different slaughter-houses throughout the country. Imported cow livers, were also analyzed for comparison with the Finnish material. The Cu content in the Finnish animals turned out to be relatively low. The imported samples had even lower contents. There seemed to be no correlation between the Cu contents in muscle, liver and kidneys. Statistical tests established that the mean Cu content in livers from Oulu was significantly higher than most of the others at the 5% level. The Zn determinations revealed the highest amounts in the muscle. No correlation between the contents in muscle, liver and kidneys was shown. The animals from Seinaejoki had the highest Zn contents, significantly different from most of the others. The imported livers did not differ much from the domestic ones with regards to the Zn content. The same was true for the Pb content. The correlation coefficients of Pb in muscles, liver and kidneys were low. The animals from Kouvola contained the highest amounts of Pb, and the mean Pb content of these animals' kidneys was significantly different from all the others. The Cd content was highest in the animals from Turku. A good correlation was observed between the Cd contents in liver and kidneys. The Cd content of the imported livers was of the same order as that of the Finnish ones. No correlation was found between the Zn, Pb and Cd contents. The amounts of Hg in Finnish cattle were very low, especially so in animals from the North of Finland. The Hg content of the imported samples was of the same order as the figures recorded from the South of Finland. 24 references, 5 tables.

  9. Biotechnology as a competitive edge for the Finnish forest cluster

    OpenAIRE

    Hakala, Terhi

    2007-01-01

    In this study we have collected information by interviewing all identified parties within the Finnish forest sector who might have a potential biotechnology connection : university research groups, research institutions, small and medium-sized biotechnology-companies and up to the largest forest companies. The ultimate goal was to assess how resources have been allocated and biotechnologies utilized within the value chain of the entire forest sector. This study aimed at providing answers to t...

  10. Biotechnology as a Competitive Edge for the Finnish Forest Cluster

    OpenAIRE

    Hakala, Terhi; Haltia, Olli; Hermans, Raine; Kulvik, Martti; Nikinmaa, Hanna; Porcar-Castell, Albert; Pursula, Tiina

    2007-01-01

    In this study we have collected information by interviewing all identified parties within the Finnish forest sector who might have a potential biotechnology connection : university research groups, research institutions, small and medium-sized biotechnology-companies and up to the largest forest companies. The ultimate goal was to assess how resources have been allocated and biotechnologies utilized within the value chain of the entire forest sector. This study aimed at providing answers to t...

  11. Americium in the Finnish environment

    Energy Technology Data Exchange (ETDEWEB)

    Lehto, J. (Helsinki Univ., Lab. of Radiochemistry (Finland))

    2009-07-01

    This paper reviews studies on environmental americium,241 Am, in Finland. There are two sources of americium in the Finnish environment: fallouts from nuclear weapons tests in the 1950s and 1960s and from the Chernobyl accident in 1986, the former constituting around 98% of the total environmental load. The weapons test fallout was distributed more or less uniformly over Finland, while the Chernobyl fallout was deposited on a sector from southwestern coast to northeast. The total deposition of 241 Am in Finland is approximately 20 Bq m-2 and the amount is still somewhat increasing due to decay of 241 Pu. In this paper, the distribution and migration of americium in forest and aquatic environments is described. Americium concentrations in natural waters, sediments, soils, vegetation and fishes are given. In addition, the behaviour of americium in the food chain from lichen via reindeer into man is discussed. Radiation doses to humans due to the environmental americium in Finland are of no practical importance (orig.)

  12. New Finnish reference for head circumference from birth to 7 years.

    Science.gov (United States)

    Karvonen, Marjo; Hannila, Marja-Leena; Saari, Antti; Dunkel, Leo

    2012-06-01

    In the evaluation of the growth of head circumference (HC), charts depicting normal growth are of paramount importance. Current Finnish HC growth charts are based on data from only 130 children born 1953-1964. As a secular trend in HC growth has been reported, we updated the HC charts using a large sample of contemporary HC data. Mixed cross-sectional HC data of 19,715 healthy subjects aged 0-7 years were collected from primary health care providers. References for HC for age and HC/height ratio for age were fitted using generalized additive models for location, scale, and shape (GAMLSS). Increased HC for age was seen particularly after 2 years of age in both genders compared to the 1953-1964 reference. The SD for HC was remarkably larger in the 1953-1964 reference. The proportion of 1986-2008 reference subjects exceeding the +2 SD limit of the 1953-1964 reference was much bigger than the proportion below -2 SD. Because of the secular change in HC growth, the HC reference has to be renewed periodically. The new Finnish reference for HC for age should be implemented for monitoring HC growth of children in Finland.

  13. Exposure of Finnish population to solar UV radiation and consequent carcinogenic effects

    Energy Technology Data Exchange (ETDEWEB)

    Huurto, L; Jansen, C [Turku Univ. Hospital, Turku (Finland); Jokela, K [Finnish Centre for Radiation and Nuclear Safety, Helsinki (Finland)

    1997-12-31

    Depletion of stratospheric ozone increases irradiance of terrestrial ultraviolet (UV) radiation at short wavelengths, which may be harmful to the human health. To understand quantitatively the risks caused by increasing UV radiation to the Finnish population, the actual UV exposure of the population has to be assessed. It was shown that the snow reflection increases the UV exposure to the face and eyes particularly in the northern Finland. In 1993 exceptionally low ozone levels persisted up to the end of May, which resulted in a theoretical increase in the annual UV dose ranging from 8 % to 13 % in Finland. The maximal increase in the measured erythemally effective dose rate was 34 % on 23 April, when compared with the theoretical normal value. During this study exposure models have been developed. The models have been combined them with Green`s radiation transfer model to estimate annual facial UV doses received by different groups of Finnish population. Also, an updated estimate for increase in skin cancer incidence due to the ozone depletion is presented. It is estimated that the maximal increase in UV doses caused by the depletion of the stratospheric ozone will be 12 % in the first years of the next century in Finland. This may result in increase in skin carcinomas by 20-30 % if the people do not improve their protection against solar UV radiation. At the moment the annual facial UV dose of the Finnish indoor worker varies from 3 % to 6 % of the annual ambient dose. In the worst case an outdoor worker may receive even 16% of the annual ambient dose. However, the doses received by indoor workers during vacation to an untanned skin may be more harmful due to the increased risk of malignant melanoma.

  14. Exposure of Finnish population to solar UV radiation and consequent carcinogenic effects

    Energy Technology Data Exchange (ETDEWEB)

    Huurto, L.; Jansen, C. [Turku Univ. Hospital, Turku (Finland); Jokela, K. [Finnish Centre for Radiation and Nuclear Safety, Helsinki (Finland)

    1996-12-31

    Depletion of stratospheric ozone increases irradiance of terrestrial ultraviolet (UV) radiation at short wavelengths, which may be harmful to the human health. To understand quantitatively the risks caused by increasing UV radiation to the Finnish population, the actual UV exposure of the population has to be assessed. It was shown that the snow reflection increases the UV exposure to the face and eyes particularly in the northern Finland. In 1993 exceptionally low ozone levels persisted up to the end of May, which resulted in a theoretical increase in the annual UV dose ranging from 8 % to 13 % in Finland. The maximal increase in the measured erythemally effective dose rate was 34 % on 23 April, when compared with the theoretical normal value. During this study exposure models have been developed. The models have been combined them with Green`s radiation transfer model to estimate annual facial UV doses received by different groups of Finnish population. Also, an updated estimate for increase in skin cancer incidence due to the ozone depletion is presented. It is estimated that the maximal increase in UV doses caused by the depletion of the stratospheric ozone will be 12 % in the first years of the next century in Finland. This may result in increase in skin carcinomas by 20-30 % if the people do not improve their protection against solar UV radiation. At the moment the annual facial UV dose of the Finnish indoor worker varies from 3 % to 6 % of the annual ambient dose. In the worst case an outdoor worker may receive even 16% of the annual ambient dose. However, the doses received by indoor workers during vacation to an untanned skin may be more harmful due to the increased risk of malignant melanoma.

  15. Self-Reported Bruxism and Symptoms of Temporomandibular Disorders in Finnish University Students.

    Science.gov (United States)

    Huhtela, Outi S; Näpänkangas, Ritva; Joensuu, Tiina; Raustia, Aune; Kunttu, Kristina; Sipilä, Kirsi

    2016-01-01

    To evaluate the prevalence of self-reported bruxism and symptoms of temporomandibular disorders (TMD) and to investigate their association in academic and applied science university students in Finland. The data were gathered from 4,403 Finnish students included in the Finnish Student Health Survey 2012. The comprehensive questionnaire included five questions concerning bruxism and TMD symptoms. Bivariate associations between self-reported bruxism and TMD symptoms were evaluated using chi-square tests, and logistic regression model was used with age and gender as factors. Sleep bruxism was reported by 21.0% of women and by 12.5% of men, awake bruxism by 2.0% of women and by 2.8% of men, and both sleep and awake bruxism by 7.2% of women and by 3.2% of men. TMD pain was reported by 25.9% of women and by 11.4% of men and temporomandibular joint (TMJ) pain on jaw movement by 9.6% of women and by 4.2% of men. Report of sleep bruxism increased the risk for all TMD symptoms in both genders. Among women, report of awake bruxism increased the risk for TMD pain and TMJ pain on jaw movement. Reporting stress as a perpetuating factor for TMD pain increased the risk for both sleep and awake bruxism in both genders. The logistic regression analysis (including age and gender) showed that report of sleep bruxism and/or awake bruxism was associated with TMD pain (Odds Ratio [OR] = 5.71; 95% confidence interval [CI] = 4.86-6.70), TMJ pain on jaw movement (OR = 4.49; 95% CI = 3.54-5.69), and TMJ locking (OR = 2.98; 95% CI = 2.17-4.10). Bruxism and TMD symptoms are frequent in Finnish university students. Self-reported bruxism is associated with TMD symptoms, confirming earlier findings.

  16. Multilayered Word Structure Model for Assessing Spelling of Finnish Children in Shallow Orthography

    Science.gov (United States)

    Kulju, Pirjo; Mäkinen, Marita

    2017-01-01

    This study explores Finnish children's word-level spelling by applying a linguistically based multilayered word structure model for assessing spelling performance. The model contributes to the analytical qualitative assessment approach in order to identify children's spelling performance for enhancing writing skills. The children (N = 105)…

  17. Students' Views on Thesis Supervision in International Master's Degree Programmes in Finnish Universities

    Science.gov (United States)

    Filippou, Kalypso; Kallo, Johanna; Mikkilä-Erdmann, Mirjamaija

    2017-01-01

    This paper employs an intercultural perspective to examine students' views on master's thesis supervision and the roles and responsibilities of supervisors and students. The 302 respondents who answered the online questionnaire were enrolled in international master's degree programmes in four Finnish universities. The study revealed asymmetric…

  18. Methylobacterium sp. isolated from a Finnish paper machine produces highly pyruvated galactan exopolysaccharide.

    NARCIS (Netherlands)

    Verhoef, R.P.; Waard, de P.; Schols, H.A.; Siika-aho, M.; Voragen, A.G.J.

    2003-01-01

    The slime-forming bacterium Methylobacterium sp. was isolated from a Finnish paper machine and its exopolysaccharide (EPS) was produced on laboratory scale. Sugar compositional analysis revealed a 100% galactan (EPS). However, FT-IR showed a very strong peak at 1611 cm-1 showing the presence of

  19. A Moral Economy of Patents: Case of Finnish Research Universities' Patent Policies

    Science.gov (United States)

    Kauppinen, Ilkka

    2014-01-01

    The primary objective of this paper is to demonstrate the usefulness of the concept of moral economy for higher education studies through a study of Finnish research universities' patent policies. Patent policies not only stimulate the commercialization of research, they also set norms for behavior and aim to clarify how to distribute rights and…

  20. A premodern legacy: the "easy" criminalization of homosexual acts between women in the Finnish Penal Code of 1889.

    Science.gov (United States)

    Löfström, J

    1998-01-01

    Homosexual acts between women were criminalized in Finland in the 1889 Penal Code which also criminalized men's homosexual acts for the first time explicitly in Finnish legislation. The inclusion of women in the Penal Code took place without much ado. In the article it is argued that the uncomplicated juxtaposing of men and women was due to the legacy of a cultural pattern where man and woman, as categories, were not in an all-pervasive polarity to each other, for example, in sexual subjectivity. A cultural pattern of low gender polarization was typical of preindustrial rural culture, and it can help us apprehend also certain other features in contemporary Finnish social and political life, for example, women obtaining a general franchise and eligibility for the parliament first in the world, in 1906. A modern image of "public man" and "private woman" was only making its way in Finnish society; hence, there was not much anxiety at women's entry in politics, or, for that matter, at their potential for (homo)sexual subjectivity becoming recognized publicly in criminal law.

  1. FFUSION yearbook 1996. Annual report of the Finnish research unit. Association EURATOM-TEKES

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, S; Paettikangas, T [eds.; VTT Energy, Espoo (Finland)

    1997-05-01

    Finnish fusion programme (FFUSION) is one of the eleven national energy research programmes funded by the Technological Development Centre of Finland (TEKES). The FFUSION programme was fully integrated into European Fusion Programme just after Finland joined the European Union. The contract of Association Euratom and Tekes was signed in 1995 and extends to the end of 1999. Finland became a member of JET Joint Undertaking in 1996, other contracts with Euratom include NET agreement and the Staff Mobility Agreement. FFUSION programme with participating research institutes and universities forms the Fusion Research Unit of the Association Euratom-Tekes. This annual report summarises the research activities of the Finnish Research Unit in 1996. The programme consists of two parts: Physics and Technology. The research areas of the physics are: Fusion plasma engineering, Radio-frequency heating and plasma diagnostics, and Plasma-wall interactions - ion-beam studies. The technology is focused into three areas: Fusion reactor materials (first wall components and joining techniques), Remote handling and viewing systems, and Superconductors

  2. Working with children with special needs in Finnish kindergartens: Professionals and/or specialists?

    Directory of Open Access Journals (Sweden)

    Mari Nislin

    2016-02-01

    Full Text Available The aim is to investigate the links between job satisfaction of Finnish early childhood professionals (ECPs and the appreciation they receive for their work, and how these are associated with their competence to work with children with diverse needs and backgrounds. Data was collected via nationwide online survey for practitioners (n = 885 working in Finnish kindergartens. The main findings show that ECPs experience their work as satisfactory and receive appreciation from colleagues, friends and the children’s parents. It was also evident form the data that ECPs felt themselves to be incompetent to work with children with disabilities or children who had experienced trauma. This may reflect that more in-service training regarding these special education issues is needed. We argue that satisfaction, appreciation and competence, are key factors in the development of a strong professional identity, enhanced well-being at work and in other domains of life and particularly for high quality and inclusive early childhood education.

  3. The implication of the concept “nikotiiniriippuvuus” in the Finnish tobacco discussion

    Directory of Open Access Journals (Sweden)

    Hellman Matilda

    2014-12-01

    Full Text Available BACKGROUND - We examined the Finnish concept of “nikotiiniriippuvuus” (nicotine addiction or dependency in English in two public arenas in recent Finnish history (1970s, 1990s and 2000s. One was the biggest daily newspaper Helsingin Sanomat, the other the medical professional journal Lääkärilehti. DATA & DESIGN - A total of 102 print press items from the 1990s and the 2000s were collected through electronic archives with the search word “nikotiiniriippuvuus”. In addition, 41 texts were collected manually from the 1970s. RESULTS - Of the items from the 1970s, only three mentioned the concept of “riippuvuus”. Overall, we found that the use of “nikotiiniriippuvuus” has increased greatly over time. In order to know more about the implications of this, we identified some themes as meaning-making traits surrounding the concept in the materials. The analysis points to four main meaning-making functions of the concept: i agenda-setting, ii introducing and explaining self-governance techniques, iii introducing a medical understanding, and iv, mediating views on responsibility division.

  4. Service Design Outcomes in Finnish Book Industry : From Transition to Transformation

    OpenAIRE

    Nousiainen, Anu K.

    2013-01-01

    Service Design Outcomes in Finnish Book Industry - From Transition to Transformation Book industry is in transition especially due to technology advancements, converging operational environment and evolving consumer values and practices in the digital context. Simultaneously, the post-industrial paradigm shift from products to services, systems and experiences highlights the intangibles-driven economy, where existing value chain members need to find new directions and new business oppo...

  5. Communications highlights of the Finnish nuclear industry in 1997

    International Nuclear Information System (INIS)

    Heininen-Ojanperae, Marke

    1998-01-01

    Full text: The Poster will contain two major issues i.e. description of the information Centre Renovation Project at Loviisa Power Plant and a presentation with material of the Sunray III Project. The Sunray Project: The Sunray Project is a national radiation project intended for all ninth graders in the Finnish school system. The project started two years ago. Attention has been focused on the topic of radiation. The topic has been dealt with in connection with different subject as history, English, Swedish, French, Finnish, mathematics, physics, chemistry, geography, health and home economics, as well as vocational counselling. The aim of the project is to provide extensive information on the subject of radiation and radioactivity, to investigate benefits and disadvantages and to help pupils understand units and see things in correct proportions. Sunray I focused on radon, Sunray II on light. Sunray III will start this autumn and its main theme will be risk perception. The programme of the Sunray III is structured as follows: Part One: Articles on risk provided by experts from different fields. Part Two: A risk management game Part Three: A special view on natural radiation. The project is coordinated by Economic Information Bureau in cooperation with the Finnish Centre for Radiation and Nuclear Safety and two major power companies Imatran Voima and Teollisuuden Voima. The coordinator of the Sunray III Project is Mr. Matti Lattu. The Information Centre Renovation Project (ICRP) The ICRP has been a two-year project which was completed for the 20th anniversary celebration of Loviisa Nuclear Power Plant in February 1997. The main emphasis was to harness the local natural environment as much as possible. The focal point of the project was presented by a new, large-sized map as a water-colour painting (a printed version), a bird-eye view of the Haestholinen Island environment. The information signs system was completely renewed. A large sea-water aquarium containing

  6. Exploring origin of food as a source of meanings for Finnish consumers: A qualitative comparison of meanings in Swedish, German and French food

    OpenAIRE

    Luomala, Harri

    2004-01-01

    The findings show that Finnish consumers attach partly overlapping partly distinct cognitive, affective, and normative meanings to Swedish, German, and French food. Swedish and French foods are perceived healthier than German food. Finnish consumers also think that Swedish and French food is of high quality, safe and pure while in the case of German food consumers were more doubtful.

  7. Accuracy and Coverage of Diagnosis and Procedural Coding of Severely Injured Patients in the Finnish Hospital Discharge Register: Comparison to Patient Files and the Helsinki Trauma Registry.

    Science.gov (United States)

    Heinänen, M; Brinck, T; Handolin, L; Mattila, V M; Söderlund, T

    2017-09-01

    The Finnish Hospital Discharge Register data are frequently used for research purposes. The Finnish Hospital Discharge Register has shown excellent validity in single injuries or disease groups, but no studies have assessed patients with multiple trauma diagnoses. We aimed to evaluate the accuracy and coverage of the Finnish Hospital Discharge Register but at the same time validate the data of the trauma registry of the Helsinki University Hospital's Trauma Unit. We assessed the accuracy and coverage of the Finnish Hospital Discharge Register data by comparing them to the original patient files and trauma registry files from the trauma registry of the Helsinki University Hospital's Trauma Unit. We identified a baseline cohort of patients with severe thorax injury from the trauma registry of the Helsinki University Hospital's Trauma Unit of 2013 (sample of 107 patients). We hypothesized that the Finnish Hospital Discharge Register would lack valuable information about these patients. Using patient files, we identified 965 trauma diagnoses in these 107 patients. From the Finnish Hospital Discharge Register, we identified 632 (65.5%) diagnoses and from the trauma registry of the Helsinki University Hospital's Trauma Unit, 924 (95.8%) diagnoses. A total of 170 (17.6%) trauma diagnoses were missing from the Finnish Hospital Discharge Register data and 41 (4.2%) from the trauma registry of the Helsinki University Hospital's Trauma Unit data. The coverage and accuracy of diagnoses in the Finnish Hospital Discharge Register were 65.5% (95% confidence interval: 62.5%-68.5%) and 73.8% (95% confidence interval: 70.4%-77.2%), respectively, and for the trauma registry of the Helsinki University Hospital's Trauma Unit, 95.8% (95% confidence interval: 94.5%-97.0%) and 97.6% (95% confidence interval: 96.7%-98.6%), respectively. According to patient records, these patients were subjects in 249 operations. We identified 40 (16.1%) missing operation codes from the Finnish Hospital

  8. The Finnish multisource national forest inventory: small-area estimation and map production

    Science.gov (United States)

    Erkki Tomppo

    2009-01-01

    A driving force motivating development of the multisource national forest inventory (MS-NFI) in connection with the Finnish national forest inventory (NFI) was the desire to obtain forest resource information for smaller areas than is possible using field data only without significantly increasing the cost of the inventory. A basic requirement for the method was that...

  9. Dinosaurs and fossils living without dangerous tools: Social representations of computers and the Internet by elderly Finnish and American non-users

    Directory of Open Access Journals (Sweden)

    Päivi Rasi (previously Hakkarainen

    2014-11-01

    Full Text Available This study compares the computer- and Internet-related conceptions of Finnish and American elderly people who deliberately refuse to use the Internet. It seeks to answer the following questions based on various social representations: Are there similarities and differences in the way the Finnish and American respondents classify the computer and the Internet? Are there similarities and differences in the images the Finnish and American respondents use to depict the computer and the Internet? How do the social representations of the computer and the Internet express the respondents’ distinct identities, history and culture? An analysis of written accounts provided by elderly Finnish and American people showed that both groups expressed an understanding of the computer and the Internet as a ‘Tool and Thing’ and ‘Danger’. However, differences existed between their understanding of the computer as a ‘Depriver of Freedom’ and ‘Marker of Differences’. The study concludes that their distinct identities, interests, history and culture may be some of the factors that limit their motivation and capacity to welcome and use the computer. To promote digital inclusion, the elderly should be provided with Internet-related information, training and support. At the same time, however, digital inclusion policies should also encompass a choice for Internet non-use.

  10. Finnish Mentor Mathematics Teachers' Views of the Teacher Knowledge Required for Teaching Mathematics

    Science.gov (United States)

    Asikainen, Mervi A.; Pehkonen, Erkki; Hirvonen, Pekka E.

    2013-01-01

    Seven Finnish mentor mathematics teachers were interviewed about their views regarding the teacher knowledge required for teaching mathematics. The results of the interviews revealed not only the teachers' spontaneous views of the knowledge base needed for effective mathematics teaching but also their views of the particular types of teacher…

  11. Towards ICT in Everyday Life in Finnish Schools: Seeking Conditions for Good Practices

    Science.gov (United States)

    Niemi, Hannele; Kynaslahti, Heikki; Vahtivuori-Hanninen, Sanna

    2013-01-01

    The article discusses how to strengthen educational use of information and communication technology (ICT) in Finnish schools. The conceptions and experiences of the successful integration of ICT in everyday school settings are reported. Participant observations in 20 schools in different parts of Finland were carried out, including discussions…

  12. Evaluation of current care effectiveness: a survey of hypertension guideline implementation in Finnish health centres

    DEFF Research Database (Denmark)

    Alanen, Seija I; Johannala-Kemppainen, Riitta; Ijäs, Jarja J

    2007-01-01

    OBJECTIVE: To assess the extent and style of implementation of the Hypertension Guideline (HT Guideline) in Finnish primary health centres, and to identify a scale of contrasting implementation styles in the health centres (with the two ends of the scale being referred to as information...... implementers or disseminators respectively). DESIGN: A cross-sectional study. Development of a questionnaire and criteria for assessing the extent and style of implementation of the HT Guideline. SETTING: Primary healthcare. SUBJECTS: All head physicians and senior nursing officers in Finnish health centres (n...... =290). MAIN OUTCOME MEASURES: The extent of adoption of the HT Guideline in health centres and the characteristics associated with the implementation style. RESULTS: Responses were received from 410 senior medical staff (246 senior nursing officers and 164 head physicians) representing altogether 264...

  13. Finnish EPR Olkiluoto 3. The world's first third-generation reactor now under construction

    International Nuclear Information System (INIS)

    2007-01-01

    The EPR was developed by Framatome and Siemens KWU (the nuclear division of Siemens), whose nuclear activities were combined in January 2001 to form Framatome ANP, now AREVA NP. The French electricity utility EDF (Electricite de France), together with the major German utilities, played an active role in the project. The safety authorities of the two countries joined forces to bring their respective safety standards into line and draw up joint design rules for the new reactor. On December 18, 2003, the consortium formed by AREVA and Siemens - and led by AREVA - signed a contract with TVO for the turnkey construction of the EPR. The overall Olkiluoto 3 project cost has been estimated by TVO at around euros 3 Billion. TVO is responsible for the overall project management and licensing process with the Finnish Safety Authority STUK. In the pre-qualification phase, STUK concluded that the EPR can meet the Finnish licensing requirements. All specific comments will be taken into account for the realization of the project. In January 2005, STUK emphasized in its safety assessment that the evolutionary EPR design compared to predecessor product lines has been further enhanced by AREVA. This paper presents first, The Finnish energy situation (Electricity consumption and supply, Finland's Kyoto CO 2 cutback, Competitiveness of nuclear power), and then the EPR in Olkiluoto (General schedule of responsibilities, Important milestones of the project). Finally, the EPR third-generation and advanced reactor is presented with its position in the international competition (Targeted design objectives, Main characteristics, competitiveness, safety, Additional measures to prevent the occurrence of events likely to damage the core, Increased protection against the consequences of core melt)

  14. Finnish-Karelian symposium on mire conservation and classification

    International Nuclear Information System (INIS)

    Heikkilae, H.

    1995-01-01

    This publication is a collection of papers based on presentations in a Finnish-karelischen symposium on the classification and conservation of mires, held in 1992. The symposium was arranged according to the contract of cooperation between the ministries of environment of Finland and Karelia, about mire conservation research. The aim of the cooperation is to improve the conservation of mires in the biogeographically uniform area of Eastern Fennoscandia, taking into account the great differences in mire utilization in Finland and Karelia. Another aim is to develop and unify the research methods. Paludification and development of mires is treated in three papers. Lake terrestrialization in Finland has been studied. Mires in fault valleys on the northwestern side of Lake Onega in Karelia have interesting stratigraphical features. The nutrient status of mires at different stages of development has been studied in Karelia, and the usability of the method is studied. The annual growth of hummock and lawn layer Sphagna and its dependence on the weather of the growth period as been studied in Karelia. The relationships of carbon balance, growth and different forms of mire utilization in Finland have been studied. The vegetation of the mires in Vodlozersky national park in Karelia has been studied in Finnish-Karelian cooperation. The main features of the vegetation are presented in one paper. For articles deal with mire conservation. Threatened mire plants and their conservation are treated in one paper. Another deals with the present state of mires in the raised bog zone in Finland, and the success of mire reservation. Gaps in mire conservation and possibilities to improve the protection of mires in Finland have been studied

  15. Twin study of heritability of eating bread in Danish and Finnish men and women

    DEFF Research Database (Denmark)

    Hasselbalch, Ann Louise; Silventoinen, Karri; Keskitalo, Kaisu

    2010-01-01

    Bread is an elementary part of the western diet, and especially rye bread is regarded as an important source of fibre. We investigated the heritability of eating bread in terms of choice of white and rye bread and use-frequency of bread in female and male twins in Denmark and Finland. The study...... cohorts included 575 Danish (age range 18-67 years) and 2009 Finnish (age range 22-27 years) adult twin pairs. Self-reported frequency of eating bread was obtained by food frequency questionnaires. Univariate models based on linear structural equations for twin data were used to estimate the relative...... magnitude of the additive genetic, shared environmental and individual environmental effects on bread eating frequency and choice of bread. The analysis of bread intake frequency demonstrated moderate heritability ranging from 37-40% in the Finnish cohort and 23-26% in the Danish cohort. The genetic...

  16. Openness and Continuous Collaboration as the Foundation for Entrepreneurial Discovery Process in Finnish Regions

    Directory of Open Access Journals (Sweden)

    Mona ROMAN

    2017-12-01

    Full Text Available Entrepreneurial discovery process (EDP is a bottom-up process engaging regional actors from academic, business, government and civil society together to identify new market opportunities and overcome the potential barriers to innovation. While EDP forms the key principle behind the smart specialization policy of European Commission, its operationalization has remained a challenge. We adopted a grounded theory approach to explore the dynamics of EDP through a case study in Finnish regions. Our aim is to identify the key underlying factors of EDP. Based on the semi-structured interviews with 10 Finnish regions during September 2016, we identified openness, engaging, focused networking and continuous collaboration as the key factors underlying EDP. Our findings contribute to the theoretical debate on what constitutes EDP in the context of smart specialization. We also provide examples for policymakers how to implement these factors based on our case study.

  17. Effects of a Group Intervention on the Career Network Ties of Finnish Adolescents

    Science.gov (United States)

    Jokisaari, Markku; Vuori, Jukka

    2011-01-01

    The authors evaluated how a group-based career intervention affected career network ties among Finnish adolescents as they made educational choices and prepared for their transition to secondary education. They examined the career-related network ties of 868 students during their last year in comprehensive school (junior high school) in a…

  18. Sixth Finnish research seminar on solid waste management. Proceedings; Kuudes jaetehuollon tutkimusseminaari 2001

    Energy Technology Data Exchange (ETDEWEB)

    Pelkonen, M. (ed.)

    2001-07-01

    The sixth Finnish seminar on solid waste management includes mostly question regarding landfills. The focus has been on the quality of waste and the pre-treatment before disposal as well as on the control of landfill emissions. Other questions discussed at the seminar included organic waste treatment and waste management systems.

  19. University Applicants' Critical Thinking Skills: The Case of the Finnish Educational Sciences

    Science.gov (United States)

    Utriainen, Jukka; Marttunen, Miika; Kallio, Eeva; Tynjälä, Päivi

    2017-01-01

    This study investigates the quality of the critical thinking skills of applicants (n = 77) seeking entry to the faculty of educational sciences in a Finnish university and how these skills are associated with the applicant's age, previous higher education experience, and matriculation and entrance examination scores. The data consist of the…

  20. The role of peat in finnish greenhouse gas balances

    International Nuclear Information System (INIS)

    Crill, P.; Hargreaves, K.; Korhola, A.

    2000-06-01

    Over the past, total annual greenhouse gas (GHG) emissions from Finland, not considering land use change, forestry or peatlands, have remained between 70 000 and 80 000 Gg of CO 2 equivalents. A large portion of which (84% in 1998) is from energy and energy related sources. Signatory members to the 1997 Kyoto protocol of the United Nation's Framework Convention on Climate Change convention, which includes Finland, are compelled to assess their emissions at the national level. This study was undertaken to examine the issues of the role of Finnish peatlands in the national greenhouse gas inventory specifically within the context of the utilization of peatlands for energy production. Our analysis is essentially a literature review and assessment of what has been measured from Finnish peatlands. We are particularly fortunate that there have been a series of recent Ph.D. theses published at the Universities of Helsinki and Joensuu and graduate work at the University of Kuopio on carbon dynamics and greenhouse gas exchange in Finnish peatlands that have both expanded our database and our understanding of peatland processes. Chapter 1 provides a background of the role of peatlands in carbon cycling within the context of changing climate and land use. In Finland about 56 x 103 ha of peatland area were being harvested in 1997, 94% for energy. Even though this is a relatively small area, the implications, on a national scale, for GHG fluxes and carbon balance can be significant The magnitude of GHG fluxes and a qualitative assessment of extant data quality and quantity under different Finnish land use forms and activities is considered in chapter 2. CO 2 fluxes derived from long term C accumulation rates indicate that 3 010 Gg CON and 9 400 Gg CO 2 are sequestered annually from the atmosphere into undrained and peatlands drained for forestry, respectively. Peatlands drained for agriculture emit CO 2 at a rate of 3 200-7 800 Gg annually. Peat harvesting activities and

  1. Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

    OpenAIRE

    Umar, Asad; Boland, C. Richard; Terdiman, Jonathan P.; Syngal, Sapna; de la Chapelle, Albert; Rüschoff, Josef; Fishel, Richard; Lindor, Noralane M.; Burgart, Lawrence J.; Hamelin, Richard; Hamilton, Stanley R.; Hiatt, Robert A.; Jass, Jeremy; Lindblom, Annika; Lynch, Henry T.

    2004-01-01

    Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is a common autosomal dominant syndrome characterized by early age at onset, neoplastic lesions, and microsatellite instability (MSI). Because cancers with MSI account for approximately 15% of all colorectal cancers and because of the need for a better understanding of the clinical and histologic manifestations of HNPCC, the National Cancer Institute hosted an international workshop on HNPCC in 1996, which led to...

  2. Marketing the Eco-Efficiency of a Finnish Product in Russia

    OpenAIRE

    Sattarova, Asiia

    2016-01-01

    The purpose of this qualitatitive research was to find the way for a Finnish company to market the eco-efficient characteristics as an advantage of their products and bring the message effectively to their consumers in Russia. The core objective was to create a strategic marketing plan; the goal was to work out an efficient strategy, practical marketing steps and effective solutions. The first theory part focused on the comparison of general eco-awareness in Europe and Russia. The part rev...

  3. Airline Merchandising: Focus on leisure travel on the Finnish market

    OpenAIRE

    Laurila, Tarja

    2015-01-01

    This thesis focuses on one of current trends: merchandising. The purpose of this thesis is to find out the experiences and opinions of leisure travellers and leisure travel agents in terms of booking ancillaries for flights. Based on those findings, the aim is to find out alternative ways to boost the sales of ancillaries. The commis-sioner for this thesis is Amadeus Finland Oy and the target group is the Finnish leisure travel market. The research was conducted by creating two online su...

  4. Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women

    DEFF Research Database (Denmark)

    Antignac, J P; Main, K M; Virtanen, H E

    2016-01-01

    The present study compares concentrations and chemical profiles of an extended range of persistent organic pollutants (dioxins, polychlorobiphenyls, brominated flame retardants and organochlorine pesticides) in breast milk samples from French (n = 96), Danish (n = 438) and Finnish (n = 22) women....... Median exposure levels observed in French women (WHO-TEQ2005 PCDD/F = 6.1 pg/g l.w., WHO-TEQ2005 dl-PCB = 4.3 pg/g l.w., sum of 6 ndl-PCB = 85.2 ng/g l.w., sum of 7 i-PBDE = 1.5 ng/g l.w.) appeared overall lower than in Danish and Finnish women for all examined POPs, except for α-HBCD (2-fold higher...... level at 0.6 ng/g l.w.). Furthermore, the observed exposure levels of dioxins and PCBs were higher in Danish women (WHO-TEQ2005 PCDD/F = 13.2 pg/g l.w., WHO-TEQ2005 dl-PCB = 6.6 pg/g l.w., sum of 6 ndl-PCB = 162.8 ng/g l.w.) compared to Finnish women (WHO-TEQ2005 PCDD/F = 9.0 pg/g l.w., WHO-TEQ2005 dl...

  5. Evolutionary trends of European bat lyssavirus type 2 including genetic characterization of Finnish strains of human and bat origin 24 years apart.

    Science.gov (United States)

    Jakava-Viljanen, Miia; Miia, Jakava-Viljanen; Nokireki, Tiina; Tiina, Nokireki; Sironen, Tarja; Tarja, Sironen; Vapalahti, Olli; Olli, Vapalahti; Sihvonen, Liisa; Liisa, Sihvonen; Huovilainen, Anita; Anita, Huovilainen

    2015-06-01

    Among other Lyssaviruses, Daubenton's and pond-bat-related European bat lyssavirus type 2 (EBLV-2) can cause human rabies. To investigate the diversity and evolutionary trends of EBLV-2, complete genome sequences of two Finnish isolates were analysed. One originated from a human case in 1985, and the other originated from a bat in 2009. The overall nucleotide and deduced amino acid sequence identity of the two Finnish isolates were high, as well as the similarity to fully sequenced EBLV-2 strains originating from the UK and the Netherlands. In phylogenetic analysis, the EBLV-2 strains formed a monophyletic group that was separate from other bat-type lyssaviruses, with significant support. EBLV-2 shared the most recent common ancestry with Bokeloh bat lyssavirus (BBLV) and Khujan virus (KHUV). EBLV-2 showed limited diversity compared to RABV and appears to be well adapted to its host bat species. The slow tempo of viral evolution was evident in the estimations of divergence times for EBLV-2: the current diversity was estimated to have built up during the last 2000 years, and EBLV-2 diverged from KHUV about 8000 years ago. In a phylogenetic tree of partial N gene sequences, the Finnish EBLV-2 strains clustered with strains from Central Europe, supporting the hypothesis that EBLV-2 circulating in Finland might have a Central European origin. The Finnish EBLV-2 strains and a Swiss strain were estimated to have diverged from other EBLV-2 strains during the last 1000 years, and the two Finnish strains appear to have evolved from a common ancestor during the last 200 years.

  6. Immediate effects of the Finnish resonance tube method on behavioral dysphonia.

    Science.gov (United States)

    Paes, Sabrina Mazzer; Zambon, Fabiana; Yamasaki, Rosiane; Simberg, Susanna; Behlau, Mara

    2013-11-01

    To investigate the immediate effects of the Finnish resonance tube method for teachers with behavioral dysphonia. Twenty-five female teachers (m=39.9 years of age) with at least a 5-year history of dysphonia were included. Additional inclusion criteria were the diagnosis of chronic behavioral dysphonia with an indication for speech therapy and the absence of any prior speech therapy. Subjects produced three sets of 10 tokens of sustained phonation with a 1-minute rest interval between tokens into a 27-cm glass tube immersed in at least 2 cm of water. Voice samples were recorded before and after these sets. The effects of these exercises were evaluated by self-assessment, auditory perceptual analysis, and acoustic evaluation involving extraction of fundamental frequency and visual spectrographic analysis. Sixty-eight percent of the teachers reported increased phonatory comfort and 52% reported improved voice quality after performing the exercises. Perceptual analysis indicated improved voice quality in the samples of counting numbers, confirmed by decreased instability, subharmonics, noise in high frequencies, and the tendency for reduced low frequency noise on spectrographic evaluation. Additionally, mean fundamental frequency decreased. The Finnish resonance tube method increased phonatory comfort and vocal changes suggestive diminished hyperfunction. Copyright © 2013 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  7. Genome scan of clot lysis time and its association with thrombosis in a protein C deficient kindred

    Science.gov (United States)

    Meltzer, M.E.; Hasstedt, S.J.; Vossen, C.Y.; Callas, P.W.; de Groot, Ph.G.; Rosendaal, F.R.; Lisman, T.; Bovill, E.G.

    2011-01-01

    Summary Background Previously we found increased clot lysis time (CLT), as measured with a plasma-based assay, to increase the risk of venous thrombosis in two population-based case-control studies. Genes influencing CLT are yet unknown. Objectives and Patients/Methods We tested CLT as risk factor for venous thrombosis in Kindred Vermont II (n=346), a pedigree suffering from a high thrombosis risk, partially attributable to a type I protein C deficiency. Furthermore we tested for quantitative trait loci (QTL) for CLT using variance component linkage analysis. Results Protein C deficient family members had shorter CLT than non-deficient members (median CLT 67 versus 75 minutes). One standard deviation increase in CLT increased risk of venous thrombosis 2.4-fold in non-deficient family members. Protein C deficiency without elevated CLT increased risk 6.9-fold. Combining both risk factors yielded a 27.8-fold increased risk. Heritability of CLT was 42-52%. We found suggestive evidence of linkage on chromosome 11 (62 cM), partly explained by the prothrombin 20210A mutation, and on chromosome 13 (52 cM). Thrombin Activatable Fibrinolysis Inhibitor genotypes did not explain the variation in CLT. Conclusion Hypofibrinolysis appears to increase thrombosis risk in this family especially in combination with protein C deficiency. Protein C deficiency is associated with short CLT. CLT is partly genetically regulated. Suggestive QTL were found on chromosome 11 and 13. PMID:21575129

  8. Hybridisation or Ousterisation? The Case of Local Accountability Policy in Finnish Early Childhood Education

    Science.gov (United States)

    Paananen, Maiju; Lipponen, Lasse; Kumpulainen, Kristiina

    2015-01-01

    Drawing on the analytic concept of imaginary, this study investigates policy hybridisation in the Finnish early childhood education. Specifically, it illuminates how the interplay between different imaginaries enabled the neoliberal imaginary to oust the social-democratic imaginary through a tripartite process in a case of local productivity…

  9. FFUSION yearbook 1997. Annual report of the Finnish fusion research unit. Association EURATOM-TEKES

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, S; Paettikangas, T [eds.; VTT Energy, Espoo (Finland)

    1998-02-01

    Finnish fusion programme (FFUSION) is one of the eleven national energy research programmes funded by the Technological Development Centre of Finland (TEKES). The FFUSION programme was fully integrated into European Fusion Programme just after Finland joined the European Union. The contract of Association Euratom and Tekes was signed in 1995 and extends to the end of 1999. Finland became a member of JET Joint Undertaking in 1996, other contracts with Euratom include NET agreement and the Staff Mobility Agreement. FFUSION programme with participating research institutes and universities forms the Fusion Research Unit of the Association Euratom-Tekes. This annual report summarises the research activities of the Finnish Research Unit in 1997. The programme consists of two parts: Physics and Technology. The research areas of the physics are: Fusion plasma engineering, and Radio-frequency heating and Plasma diagnostics. The technology is focused into three areas: Fusion reactor materials (first wall components and joining techniques), Remote handling and viewing systems, and Superconductors

  10. Discursive turns from 'Bildung' to managerialism: Memory-work of the Finnish adult education generations

    Directory of Open Access Journals (Sweden)

    Karin Filander

    2012-10-01

    Full Text Available The article focuses on the struggles over ethos in academic adult education tradition that grows from the frameworks of student generations in Finnish adult education. It brings together elements of present-day analysis and historically sensitizing memory data on generations of the 1960s, 1970s and 1980s. My interest here lies in how the rhetoric of lifelong learning and education has revised the basic assumptions of adult education. The data suggest that the dominant narrative of adult education is increasingly the discourse of marketization. Finnish present-day student generations seem to have lost their intrinsic connections with the Scandinavian traditions of popular enlightenment and the values of equality and basic logics enabling 'second chances' for all adult citizens within the Nordic welfare state. One of the results of the analysis was the following question: Should we reinvent adult education again from the standpoint of sustainable development of 'ordinary people'?

  11. Reliability and Validity Study of the Finnish Adaptation of Scoliosis Research Society Questionnaire Version SRS-30.

    Science.gov (United States)

    Kyrölä, Kati; Järvenpää, Salme; Ylinen, Jari; Mecklin, Jukka-Pekka; Repo, Jussi Petteri; Häkkinen, Arja

    2017-06-15

    A prospective clinical study to test and adapt a Finnish version of the Scoliosis Research Society 30 (SRS-30) questionnaire. The aim of this study was to perform cross-cultural adaptation and evaluate the validity of the adapted Finnish version of the SRS-30 questionnaire. The SRS-30 questionnaire has proved to be a valid instrument in evaluating health-related quality of life (HRQoL) in adolescent and adult population with spine deformities in the United States. Multinational availability requires cross-cultural and linguistic adaptation and validation of the instrument. The SRS-30 was translated into Finnish using accepted methods for translation of quality-of-life questionnaires. A total of 274 adult patients with degenerative radiographic sagittal spinal disorder answered the questionnaire with sociodemographic data, RAND 36-item health survey questionnaire (RAND Corp. Health, Santa Monica, CA, US), Oswestry disability index, DEPS depression scale, and Visual Analog Scale (VAS) back and leg pain scales within 2 weeks' interval. The cohort included patients with and without previous spine surgery. Internal consistency and validity were tested with Cronbach α, intraclass correlation (ICC), standard error of measurement, and Spearman correlation coefficient with 95% confidence intervals (CIs). The internal consistency of SRS-30 was good in both surgery and nonsurgery groups, with Cronbach α 0.853 (95% CI, 0.670 to 0.960) and 0.885 (95% CI, 0.854 to 0.911), respectively. The test-retest reproducibility ICC of the SRS-30 total and subscore domains of patients with stable symptoms was 0.905 (95% CI, 0.870-0.930) and 0.904 (95% CI, 0.871-0.929), respectively. The questionnaire had discriminative validity in the pain, self-image, and satisfaction with management domains compared with other questionnaires. The SRS-30 questionnaire proved to be valid and applicable in evaluating HRQoL in Finnish adult spinal deformity patients. It has two domains related to deformity

  12. High Performance Education Fails in Sustainability?--A Reflection on Finnish Primary Teacher Education

    Science.gov (United States)

    Wolff, Lili-Ann; Sjöblom, Pia; Hofman-Bergholm, Maria; Palmberg, Irmeli

    2017-01-01

    Sustainability is internationally often emphasized as an essential aim of higher education, but more as a principle than on the practical level. This is also obvious in the academic education of primary teachers in Finland. Therefore, it is a great challenge for Finnish teachers to include sustainability in their teaching and everyday life in…

  13. The Influences of an Exemplary Ballet Teacher on Students' Motivation: "The Finnish Way"

    Science.gov (United States)

    Chua, Joey

    2017-01-01

    This ethnographic case story aims to illuminate the instructional practices and decisions of an exemplary ballet teacher, Minna Stenvall at the Finnish National Opera Ballet School. Minna is considered to be exemplary in her field because she received the Best Ballet Pedagogue Award in 2014. Spurred on by the literature on the significant role…

  14. Operation of Finnish nuclear power plants. Quarterly report, 1st quarter 1998

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1998-11-01

    Quarterly reports on the operation of Finnish NPPs describe events and observations relating to nuclear and radiation safety that the Radiation and Nuclear Safety Authority (STUK) considers safety significant. Safety improvements at the plants are also described. The report includes a summary of the radiation safety of plant personnel and the environment and tabulated data on the plants' production and load factors. The Finnish NPP units were in power operation for the whole first quarter of 1998. All the units were in long-term test operation at uprated power level authorised by STUK. The load factor average of the plant units was 100.8%. An oil leak at Olkiluoto NPP Unit 2 caused an ignition that was promptly extinguished. A subsequent appraisal of the event disclosed deficiencies in the functioning of the plant unit's operating organization and the event was classified INES level 1. Other events in this quarter had no bearing on nuclear or radiation safety. Occupational doses and radioactive releases off-site were below authorized limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.)

  15. Finnish WorldSkills Achievers’ Vocational Talent Development and School-to-Work Pathways

    Directory of Open Access Journals (Sweden)

    Laura Pylväs

    2017-08-01

    Full Text Available This paper examines the perceptions of vocational expertise and school-to-work pathways among WorldSkills Competition (WSC achievers and their co-workers and employers within the Finnish context. At the biennial international WSC, young people (aged 18-to-23 years from over 60 countries demonstrate their skills in more than 40 trades. Individualized training for this competition is provided through the cooperation of vocational institutions (e.g., expert coaches, team leaders and competition panellists and industry (e.g., mentors, sponsors, materials, equipment. Semi-structured thematic interviews (N=51 were conducted in 2013 and 2014 with former Finnish WSC medal or diploma winners (n=18 who had since begun their working lives (1-to-15 years of work experience. Their employers (n=16 and colleagues (n=17 were also interviewed. Results showed that in addition to vocation-specific knowledge and skills, problem-solving skills, creativity, social skills and self-regulatory skills were acknowledged as the most significant elements of vocational expertise. The findings also indicated that formal vocational education combined with deliberate practice and training based on expert mentoring improved the long-term career progress and vocational expertise of the WSC achievers.

  16. Psychosocial correlates of police-registered youth crime. A Finnish population-based study.

    Science.gov (United States)

    Elonheimo, Henrik; Sourander, Andre; Niemelä, Solja; Nuutila, Ari-Matti; Helenius, Hans; Sillanmäki, Lauri; Ristkari, Terja; Parkkola, Kai

    2009-01-01

    This study is focused on psychosocial correlates of youth crime in a sample of 2330 Finnish boys born in 1981. Two kinds of data were combined: questionnaires completed by the boys at call-up in 1999 and crime registered in the Finnish National Police Register between 1998 and 2001. One-fifth of the boys were registered to offending during the 4-year period in late adolescence; 14% were registered for one or two offences, 4% for three to five offences, and 3% for more than five offences. Crime accumulated heavily in those with more than five offences, as they accounted for 68% of all crime. Independent correlates of crime were living in a small community, parents' low educational level and divorce, having a regular relationship, self-reported delinquency, daily smoking, and weekly drunkenness, whereas anxious-depressiveness was reversely associated with crime. Most psychosocial problems covaried linearly with offending frequency, being particularly manifested by multiple recidivists. However, recidivists had very rarely used mental health services. The results indicate that offending and various psychosocial problems accumulate in a small minority of boys not reached by mental health services.

  17. Attributions by Team Members for Team Outcomes in Finnish Working Life

    OpenAIRE

    Valo, Maarit; Hurme, Pertti

    2010-01-01

    This study focuses on teamwork in Finnish working life. Through a wide cross-section of teams the study examines the causes to which team members attribute the outcomes of their teams. Qualitative data was collected from 314 respondents. They wrote 616 stories to describe memorable experiences of success and failure in teamwork. The stories revealed 1930 explanations. The findings indicate that both favorable and unfavorable team outcomes are perceived as being caused by ...

  18. The Finnish EMU Buffers and the Labour Market under Asymmetric Shocks

    OpenAIRE

    Alho, Kari

    2004-01-01

    The Finnish EMU buffers consist of elements built into the unemployment insurance and employment pension systems, which aim to stabilise employer contributions and employment during economic fluctuations in the EMU age. The paper simulates the role of these buffers in a hypothetical recession caused by an adverse asymmetric shock. The results show that the buffers play only a modest role in stabilising employment, although their importance increases as the shocks to the economy become greater...

  19. FFUSION yearbook 1995. Annual report of the Finnish research unit. Association EURATOM-TEKES

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, S; Paettikangas, T [eds.; VTT Energy, Espoo (Finland)

    1996-03-01

    Finnish Fusion Research Programme (FFUSION) is one of the eleven national energy research programmes funded by the Technological Development Centre of Finland (TEKES). All fusion related research in Finland is included in the FFUSION programme and it made it possible to establish a dialogue with the European Fusion Programme already two years before Finland joined the European Union. The process led to the founding of the Association Euratom-TEKES in early 1995. The contract of Association was signed in Helsinki on March 13 1995, to establish the 14th Association in the EU FFusion Programme. This annual report summarises the research activities of the Finnish Research Unit in 1995. The emphasis is on research supported by the EU Commission. The programme consists of two parts: Physics and Technology. The research areas of the physics are: Fusion plasma engineering, Radio-frequency heating and plasma diagnostics, and Plasma-wall interactions - ion-beam studies of the reactor materials. The technology is focused into three areas: Fusion reactor materials (first wall components and joining techniques), and Remote handling

  20. Digital control in Finnish power industry applications and some research and development activities

    International Nuclear Information System (INIS)

    Haapanen, P.; Winter, M.

    1986-01-01

    First applications of digital control systems in Finnish power plants stem from a few years time. There are at present in operation two conventional peat fuelled district heating power plants and two others are under construction. In existing nuclear power plants digital control systems are not used. Feasibility studies of a new fifth nuclear power plant have been carried out and also preliminary design exercises on its control systems has been done. It seems that the use of a digital control system in this plant is an alternative worthy of consideration. The existing digital control applications and future plans for their use in the Finnish power industry are described. The rest of the paper is devoted to the reliability questions. Software reliability is a new problem area emanating from the use of programmable digital systems. A description of a cooperative project on these questions between VTT and OECD Halden Project is given. VTT has also developed an interactive computer program, RELVEC, for plant and control system reliability analysis. The structure and use of this system is described

  1. Integrating mental health services: the Finnish experience

    Directory of Open Access Journals (Sweden)

    Ville Lehtinen

    2001-06-01

    Full Text Available The aim of this paper is to give a short description of the most important developments of mental health services in Finland during the 1990s, examine their influences on the organisation and provision of services, and describe shortly some national efforts to handle the new situation. The Finnish mental health service system experienced profound changes in the beginning of the 1990s. These included the integration of mental health services, being earlier under own separate administration, with other specialised health services, decentralisation of the financing of health services, and de-institutionalisation of the services. The same time Finland underwent the deepest economic recession in Western Europe, which resulted in cut-offs especially in the mental health budgets. Conducting extensive national research and development programmes in the field of mental health has been one typically Finnish way of supporting the mental health service development. The first of these national programmes was the Schizophrenia Project 1981–97, whose main aims were to decrease the incidence of new long-term patients and the prevalence of old long-stay patients by developing an integrated treatment model. The Suicide Prevention Project 1986–96 aimed at raising awareness of this special problem and decreasing by 20% the proportionally high suicide rate in Finland. The National Depression Programme 1994–98 focused at this clearly increasing public health concern by several research and development project targeted both to the general population and specifically to children, primary care and specialised services. The latest, still on-going Meaningful Life Programme 1998–2003 which main aim is, by multi-sectoral co-operation, to improve the quality of life for people suffering from or living with the threat of mental disorders. Furthermore, the government launched in 1999 a new Goal and Action Programme for Social Welfare and Health Care 2000–2003, in

  2. Social Anxiety Scale for Adolescents (SAS-A): Measuring Social Anxiety among Finnish Adolescents

    Science.gov (United States)

    Ranta, Klaus; Junttila, Niina; Laakkonen, Eero; Uhmavaara, Anni; La Greca, Annette M.; Niemi, Paivi M.

    2012-01-01

    The aim of this study was to investigate symptoms of social anxiety and the psychometric properties of the "Social Anxiety Scale for Adolescents" (SAS-A) among Finnish adolescents, 13-16 years of age. Study 1 (n = 867) examined the distribution of SAS-A scores according to gender and age, and the internal consistency and factor structure…

  3. Recent fertility patterns of Finnish women by union status: A descriptive account

    Directory of Open Access Journals (Sweden)

    Marika Jalovaara

    2013-02-01

    Full Text Available BACKGROUND Remarkably little is known about the significance of consensual unions for fertility. This is true everywhere, but the lacuna is more important in the Nordic countries where there is so much childbearing outside of marriage, mostly in consensual unions. The purpose of this paper is to help fill this hole in our knowledge for Finland. OBJECTIVE Unusually good register data enable us to study recent fertility trends by union status (married, cohabiting, neither using records for some 112,000 Finnish women, or 11Š of all women at fertile ages. METHODS Our description of fertility is based on group-specific duration-based TFRs, which is the number of children borne by a woman who remains in the group throughout her reproductive life, as computed from the fertility rates for a synthetic cohort. This is an intuitively appealing metric that has been taken into systematic use only recently. RESULTS We find substantial fertility differences between women who cohabit, women who marry directly (i.e., without pre-marital cohabitation, and women who marry their cohabitational partner. As one would also expect in Finland, cohabiting women have much lower fertility than married women. The marital TFR is highest among the directly-married and declines monotonically as the length of pre-marital cohabitation increases, even when premarital childbearing is included in the count. As far as we know the latter relationship has not been shown before, because extensive data for complete cohabitational unions have not been available for other populations. CONCLUSIONS The Finnish data are unique, even among the Nordic countries, in that they contain individual-level life histories of family dynamics that cover consensual unions from their very start. Fertility analysis would benefit if data similar to the Finnish were to become available, because analyses that rely on civil status as an indicator of union status barely add anything to what we already know

  4. The Finnish background report for the EC documentation of best available techniques for tanning industry

    Energy Technology Data Exchange (ETDEWEB)

    Kustula, V.; Salo, H.; Witick, A.; Kaunismaa, P.

    2000-08-01

    The objective of this document is to identify best available techniques (BAT) for the reduction of emissions and energy use in the tanning industry in Finland. The leather tanning industry in Finland has long traditions, dating back for centuries, but today there are only nine tanneries of any importance left. The tanneries vary in size from small, family-owned ones to large on a Finnish scale, with a staff of about 70 persons. The production of finished leather in even the largest tannery in Finland is well below the production limit (12 tonnes finished leather a day) mentioned in the IPPC-directive (96/61/EC). The range of products manufactured by the Finnish leather industry is large and includes processed leather for, e.g. footwear, clothing, furniture and intermediate products, e.g. wet-blue and crust. The hides and skins of cows, lamb, elk, reindeer and occasionally skins from other animals, e.g. horses are the main raw materials used. Some of the tanneries carry out only a part of the processing and sell their products in a treated, but not finished state. Tanneries which undertake only a part of the preparation process are reviewed in this document as well. Because of the varying size of the Finnish tanneries, the quality and quantity of emissions and environmental impacts vary considerably. The parameters used by the authorities are suspended solids (SS), biological oxygen demand (BOD), and chromium and sulphide concentration in the effluents. The quantity of waste and waste water generated is also subject to assessment by the authorities. Direct regulation of emissions is practised in Finland by issuing permits containing emission limit values. Major waste streams generated are sludge from waste water treatment plants, animal residues from the beamhouse stage, residues from tanned leather and chemicals used. Various ways of residue separation and consequently reuse and recovery are practised in most Finnish tanneries. The proteinaceous residues from the

  5. Knowledge about hereditary nonpolyposis colorectal cancer; mutation carriers and physicians at equal levels

    DEFF Research Database (Denmark)

    Domanska, Katarina; Carlsson, Christina; Bendahl, Pär-Ola

    2009-01-01

    questions about cancer risks and surveillance strategies. RESULTS: Both groups answered questions on colorectal cancer risk, surveillance and genetic testing well, whereas answers about inheritance and risks for HNPCC associated cancer were less accurate. Only half of the family members and one third......BACKGROUND: Identification and adequate management of individuals at risk for hereditary nonpolyposis colorectal cancer (HNPCC) is crucial since surveillance programmes reduce morbidity and mortality. We investigated knowledge about key features of HNPCC in at risk individuals and physicians...

  6. Exploring the Moral and Distributive Levers for Teacher Empowerment in the Finnish Policy Culture

    Science.gov (United States)

    Paulsen, Jan Merok; Hjertø, Kjell Brynjulf; Tihveräinen, Saku Petteri

    2016-01-01

    Purpose: The purpose of this paper is to explore the relationship between school leadership practices and teacher empowerment in the Finnish policy culture. Specifically, moral leadership and distributed leadership enacted by school principals are tested in a simultaneous design as predictor to two distinct yet related aspects of teachers' sense…

  7. A Comparative Analysis of PISA Scientific Literacy Framework in Finnish and Thai Science Curricula

    Science.gov (United States)

    Sothayapetch, Pavinee; Lavonen, Jari; Juuti, Kalle

    2013-01-01

    A curriculum is a master plan that regulates teaching and learning. This paper compares Finnish and Thai primary school level science curricula to the PISA 2006 Scientific Literacy Framework. Curriculum comparison was made following the procedure of deductive content analysis. In the analysis, there were four main categories adopted from PISA…

  8. Identities of Special Needs Education in the Discourse of Finnish Professors of the Field

    Science.gov (United States)

    Vehkakoski, Tanja; Sume, Helena; Puro, Erika

    2011-01-01

    This article examines both the discourses upon which Finnish special needs education professors draw when speaking about their field, and the consequent identities for it. The research material consists of theme interviews with 10 professors of special needs education and is analysed from a socio-constructionist, discourse analytical perspective.…

  9. Biodiversity in Finnish wilderness areas: Historical and cultural constraints to preserve species and habitats

    Science.gov (United States)

    Anna-Liisa Sippola

    2002-01-01

    The present status of species and habitats in Finnish wilderness areas is largely a consequence of past administrative, use, and management traditions in northern Finland. The existing wilderness legislation sets a framework for management, but historical uses and administrative decisions have influenced many prevailing practices. In addition, management of many uses...

  10. Views on safety culture at Swedish and Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Hammar, L.; Wahlstroem, B.; Kettunen, J.

    2000-02-01

    The report presents the results of interviews about safety culture at Swedish and Finnish nuclear power plants. The aim is to promote the safety work and increase the debate about safety in nuclear power plants, by showing that the safety culture is an important safety factor. The interviews point out different threats, which may become real. It is therefor necessary that the safety aspects get support from of the society and the power plant owners. (EHS)

  11. Trends of energy efficiency in Finnish road freight transport 1995-2009 and forecast to 2016

    International Nuclear Information System (INIS)

    Liimatainen, Heikki; Poellaenen, Markus

    2010-01-01

    A framework for modeling and analyzing the energy efficiency of road freight transport is presented in this paper. This framework is tested by using the data from the Finnish Goods Transport by Road statistics. The data was enhanced by calculating the fuel consumption for each trip in the data. To calculate this, weight-fuel consumption functions were estimated for each Euro-class vehicles and road type. This is a new method for analyzing the energy efficiency of road freight transport and it could be applied also in other countries gathering freight transport data with continuous company surveys. The analysis show that the energy efficiency of road freight transport in Finland improved during 1995-2002, but has declined since. The major drivers in the development have been the changes in the level of empty running and vehicle fuel efficiency. Extrapolating current statistical trends of factors that influence the energy efficiency show that the target set by the Finnish government for improving energy efficiency by 9% until 2016 will not be achieved. However, the target is possible to be achieved by a combination of small changes to some determinants. - Research highlights: →A new method for analyzing energy efficiency by adding fuel data to national freight statistics. →Energy efficiency improved in Finland from 1995 to 2002 but has declined since. →Energy efficiency in Finland is still on a good level internationally. →Target of the Finnish energy efficiency agreement was quantified for the first time in this study. →The target will not be achieved if the past trends continue.

  12. An effect from anticipation also in hereditary nonpolyposis colorectal cancer families without identified mutations

    DEFF Research Database (Denmark)

    Timshel, Susanne; Therkildsen, Christina; Bendahl, Pär-Ola

    2009-01-01

    Optimal prevention of hereditary cancer is central and requires initiation of surveillance programmes and/or prophylactic measures at a safe age. Anticipation, expressed as an earlier age at onset in successive generations, has been demonstrated in hereditary nonpolyposis colorectal cancer (HNPCC......). We specifically addressed anticipation in phenotypic HNPCC families without disease-predisposing mismatch repair (MMR) defects since risk estimates and age at onset are particularly difficult to determine in this cohort. The national Danish HNPCC register was used to identify families who fulfilled...... the Amsterdam criteria for HNPCC and showed normal MMR function and/or lack of disease-predisposing MMR gene mutation. In total, 319 cancers from 212 parent-child pairs in 99 families were identified. A paired t-test and a bivariate statistical model were used to assess anticipation. Both methods demonstrated...

  13. Production of the Finnish Wind Atlas

    DEFF Research Database (Denmark)

    Tammelin, Bengt; Vihma, Timo; Atlaskin, Evgeny

    2013-01-01

    ) the parameterization method for gust factor was extended to be applicable at higher altitudes; and (vii) the dissemination of the Wind Atlas was based on new technical solutions. The AROME results were calculated for the heights of 50, 75, 100, 125, 150, 200, 300 and 400 m, and the WAsP results for the heights of 50......, 75, 100, 125 and 150 m. In addition to the wind speed, the results included the values of the Weibull distribution parameters, the gust factor, wind power content and the potential power production, which was calculated for three turbine sizes. The Wind Atlas data are available for each grid point......The Finnish Wind Atlas was prepared applying the mesoscale model AROME with 2.5 km horizontal resolution and the diagnostic downscaling method Wind Atlas Analysis and Application Programme (WAsP) with 250 m resolution. The latter was applied for areas most favourable for wind power production: a 30...

  14. Overcoming artefact: anticipation in 284 Portuguese kindreds with familial amyloid polyneuropathy (FAP) ATTRV30M.

    Science.gov (United States)

    Lemos, Carolina; Coelho, Teresa; Alves-Ferreira, Miguel; Martins-da-Silva, Ana; Sequeiros, Jorge; Mendonça, Denisa; Sousa, Alda

    2014-03-01

    Early-onset (≤40 years) and later-onset (≥50 years) cases of familial amyloid polyneuropathy (FAP) ATTRV30M are not different entities, often coexisting in the same family, and showing anticipation (earlier age-at-onset (AO) in younger generations, usually associated with more severe phenotype). Historically, anticipation has been ascribed to ascertainment biases. Our aim was to study anticipation in a very large number of FAP kindreds, removing possible biases, and gain further insight into parent-of-origin effects. We analysed 926 parent-offspring pairs (from the Unidade Clínica de Paramiloidose roster, collected in 70 years), both clinically observed and had well-established AO, correcting for intrafamilial correlations. Women had a significantly higher AO, either for daughters (mean: 33.70, SD: 6.84) vs sons (29.43, 6.08); or mothers (39.57, 11.75) vs. fathers (35.62, 11.62). Also, 291 pairs showed marked anticipation (≥10 years); the transmitting parent was the mother in 203 pairs. Mother-son pairs showed larger anticipation (10.43, 9.34), while father-daughter pairs showed only a residual anticipation (1.23, 9.77). Gender of offspring and parents was highly significant (with no interaction). To remove possible biases, we repeated analyses: (1) excluding the proband; (2) removing pairs with simultaneous onset; and (3) excluding offspring born after 1960. Anticipation was found in all subsamples, with the same trend for a parent-of-origin effect. Noteworthy, parents with AO ≤40 years never had offspring with AO ≥50. These findings confirm anticipation as a true biological phenomenon, also in FAP ATTRV30M. Acknowledgment of anticipation may have important clinical implications in genetic counselling of offspring and in follow-up of mutation carriers.

  15. Trends in Socioeconomic Differences in Finnish Perinatal Health 1991-2006

    DEFF Research Database (Denmark)

    Gissler, Mika; Rahkonen, Ossi; Arntzen, Annett

    2009-01-01

    singletons recorded between 1991 and 2006 in the Finnish Medical Birth Register. Information on socioeconomic position was based on maternal occupation. Perinatal health was measured with six different indicators. RESULTS: The proportions of preterm, low-birth weight and SGA (small-for-gestational......-age) births remained stable during the study period, but decreased for LGA (large-for-gestational-age) births and perinatal death. After adjustment for maternal background variables, the socioeconomic differences in preterm and low-birth weight births decreased in the late 1990s and remained low thereafter...

  16. Observing relationships in Finnish adoptive families: Oulu Family Rating Scale.

    Science.gov (United States)

    Tienari, Pekka; Wynne, Lyman C; Sorri, Anneli; Lahti, Ilpo; Moring, Juha; Nieminen, Pentti; Joukamaa, Matti; Naarala, Mikko; Seitamaa, Markku; Wahlberg, Karl-Erik; Miettunen, Jouko

    2005-01-01

    Adoption studies were intended to separate genetic from environmental "causal" factors. In earlier adoption studies, psychiatric diagnostic labels for the adoptive parents were used as a proxy for the multiple dimensions of the family rearing environment. In the Finnish Adoption Study, research design provided the opportunity to study directly the adoptive family rearing environment. For this purpose 33 sub-scales were selected creating what we call Oulu Family Rating Scale (OPAS, Oulun PerheArviointiSkaala). In this paper, the manual for scoring of these sub-scales is presented.

  17. The prediction and prevention of voltage collapse in the Finnish power system

    Energy Technology Data Exchange (ETDEWEB)

    Bastman, J; Lakervi, E [Tampere Univ. of Tech. (Finland); Hirvonen, R; Kuronen, P; Hagman, E [IVO Group (Finland)

    1994-12-31

    The Finnish power system is a part of the Nordic power system (NORDEL), which includes Finland, Sweden, Norway and the eastern part of Denmark. In NORDEL the transmission distances are long, which implies that the power transmission capacities are determined by stability criteria . The methods to prevent and predict the voltage collapse during severe disturbances are studied using advances simulation program. Results are presented. (author) 10 figs., 1 tab.

  18. How do language-specific characteristics affect the acquisition of different relative clause types? Evidence from Finnish.

    Science.gov (United States)

    Kirjavainen, Minna; Kidd, Evan; Lieven, Elena

    2017-01-01

    We report three studies (one corpus, two experimental) that investigated the acquisition of relative clauses (RCs) in Finnish-speaking children. Study 1 found that Finnish children's naturalistic exposure to RCs predominantly consists of non-subject relatives (i.e. oblique, object) which typically have inanimate head nouns. Study 2 tested children's comprehension of subject, object, and two types of oblique relatives. No difference was found in the children's performance on different structures, including a lack of previously widely reported asymmetry between subject and object relatives. However, children's comprehension was modulated by animacy of the head referent. Study 3 tested children's production of the same RC structures using sentence repetition. Again we found no subject-object asymmetry. The pattern of results suggested that distributional frequency patterns and the relative complexity of the relativizer contribute to the difficulty associated with particular RC structures.

  19. Sustainable Leadership and Future-Oriented Decision Making in the Educational Governance--A Finnish Case

    Science.gov (United States)

    Metsamuuronen, Jari; Kuosa, Tuomo; Laukkanen, Reijo

    2013-01-01

    Purpose: During the new millennium the Finnish educational system has faced a new challenge: how to explain glorious PISA results produced with only a small variance between schools, average national costs and, as regards the average duration of studies, relatively efficiently. Explanations for this issue can be searched for in many different…

  20. The Soviet Union and Soviet citizens in Finnish magazines

    Directory of Open Access Journals (Sweden)

    Tuija Saarinen

    2014-07-01

    Full Text Available The focus of this article’s is to study Finnish popular journalism in 1970s and 1980s. A magazine studied in this article is Hymy (Smile, and it has been estimated that in the beginning of 1970s approximately the whole literary population of Finland read it. The purpose of this study is to analyze the different images Hymy created and published of the Soviet Union and the Soviet citizens. The central research question analyzes what kinds of issues Hymy published about the Soviet Union and its citizens before 1991. This study gives special attention to the reasons why the articles were written in the first place, and secondly, what was the nature of their content.        Hymy published 224 articles on the Soviet Union. The articles were mostly written in the spirit of criticism – not in the spirit of “friendship of the peoples” that was the official political stance of Finland toward the Soviet Union. Magazines had to be aware of the official Finnish political rhetoric concerning the relationship with the Soviet Union. Hymy as a popular magazine found a way to evade the official mandate. In Hymy, people were able to read anti-Soviet sentiments without any censoring. Therefore, Hymy not only provided its readers views and beliefs that expressed the popular beliefs and values, but also sympathized with them. The Cold War era in the 1970s and 1980s was still a post-traumatic period for Finns. The magazine Hymy was an important channel to publish stories on painful, embarrassing, and tragic subjects.

  1. Health and behavioral survey of over 8000 Finnish cats

    Directory of Open Access Journals (Sweden)

    Katariina Vapalahti

    2016-08-01

    Full Text Available A comprehensive feline health survey was conducted to reveal breed-specific inheritable diseases in Finnish pedigree cats for genetic research. Prevalences of 19 disease categories and 227 feline diseases were defined in a study population of 8175 cats belonging to 30 breeds. Dental and oral diseases with a prevalence of 28% and dental calculus and gingivitis (21% and 8%, respectively were the most prevalent disease category and diseases among all cats and in most of the breeds. An exception was Korats, which were more often affected by the diseases of the respiratory tract (23% and asthma (19%. Other prevalent disease categories affected various organ systems such as the skin (12%, the urinary system (12%, the digestive tract (11%, eyes, (10%, the musculoskeletal system (10%, and genitals of female cats (17%. Prevalent health or developmental issues included repetitive vomiting (4%, tail kink (4%, feline odontoclastic resorption lesion (FORL (4%, urinary tract infections (4%, as well as caesarean section (6% and stillborn kittens (6% among female cats. We found 57 breed-specific conditions by Fisher’s exact tests and logistic regression analyses, including 32 previously described and 19 new breed-specific diseases. The genetic defect has already been found in six of them: polycystic kidney disease (PKD, progressive retinal atrophy (PRA, hypertrophic cardiomyopathy (HCM and three types of tail malformations. Behavioral profiling revealed breed-specific traits, such as an increased human avoidance in British Short and Longhairs and a higher level of aggression in Turkish vans. Our epidemiological study reveals the overall health profile in Finnish pure and mixed breed cats and identifies many breed-specific conditions without molecular identity for genetic research.

  2. Developing e-commerce in charity setting : Case: The Finnish Seamen's Mission

    OpenAIRE

    Pirinen, Sari

    2013-01-01

    The purpose of this case study was to develop the Finnish Seamen’s Mission’s e-commerce so that it would be more effective and attract new customers and at the same time it would support organization’s marketing strategies. The main goal was to make strategic e-commerce development plan. The first theory part concentrates on strategy, planning and common strategy tools. A good solid strategy is the basis when starting and developing concepts. The second theory part concentrates on e-comme...

  3. Genome scan of clot lysis time and its association with thrombosis in a protein C-deficient kindred.

    Science.gov (United States)

    Meltzer, M E; Hasstedt, S J; Vossen, C Y; Callas, P W; DE Groot, Ph G; Rosendaal, F R; Lisman, T; Bovill, E G

    2011-07-01

     Previously, we found increased clot-lysis time (CLT), as measured with a plasma-based assay, to increase the risk of venous thrombosis in two population-based case-control studies. The genes influencing CLT are as yet unknown.  We tested CLT as risk factor for venous thrombosis in Kindred Vermont II (n = 346), a pedigree suffering from a high thrombosis risk, partially attributable to a type I protein C deficiency. Furthermore, we tested for quantitative trait loci (QTLs) for CLT, using variance component linkage analysis.  Protein C-deficient family members had shorter CLTs than non-deficient members (median CLT 67 min vs. 75 min). One standard deviation increase in CLT increased the risk of venous thrombosis 2.4-fold in non-deficient family members. Protein C deficiency without elevated CLT increased the risk 6.9-fold. Combining both risk factors yielded a 27.8-fold increased risk. The heritability of CLT was 42-52%. We found suggestive evidence of linkage on chromosome 11 (62 cM), partly explained by the prothrombin 20210A mutation, and on chromosome 13 (52 cM). Thrombin-activatable fibrinolysis inhibitor genotypes did not explain the variation in CLT. Hypofibrinolysis appears to increase thrombosis risk in this family, especially in combination with protein C deficiency. Protein C deficiency is associated with short CLT. CLT is partly genetically regulated. Suggestive QTLs were found on chromosomes 11 and 13. © 2011 International Society on Thrombosis and Haemostasis.

  4. The art of mystification: esotericism differentiated in the definition of Finnish symbolism

    Directory of Open Access Journals (Sweden)

    Nina Kokkinen

    2008-01-01

    Full Text Available This article focuses on Sarajas-Korte’s definitions that proved to be so significant to Finnish art history. In spite of the fact that her research still represents the most extensive and profound work on Finnish Symbolism, the aim here is to question some of her definitions and categorizations. Most of her concepts are puzzling, since she tends to use them in several different ways. One example of her conceptualizations is the way she uses the word esotericism and its derivatives. First of all, she seems to associate esotericism with secrecy and things hidden—in other words she follows the definition created already by the ancient Greeks. Secondly, she fuses esotericism with Symbolism as she herself defines it; hence Symbolist art is grounded on the ‘esoteric conceptions of symbols’. She also uses the word esotericism as though it would reflect the spirit of an age, as she writes for example about ‘the esoteric youth’ of the time. In addition to these three meanings, Sarajas-Korte seems to understand esotericism also by means of tradition. Her view of the esoteric tradition, however, is quite inclusive, since it seems to contain everything from the secret societies of Joséphin Péladan to the stories of the Bible and the Ramayana.

  5. To have and to hold: personnel shortage in a Finnish healthcare organisation.

    Science.gov (United States)

    Heilmann, Pia

    2010-07-01

    Retirements of baby boomers will create a talent shortage in Finnish health care. Concurrently, difficulties exist in recruiting new personnel. This paper provides an overview concerning the bottlenecks in talent management in a Finnish hospital, and finds solutions for recruitment and retention problems of healthcare professionals (nurses and physicians). Because the healthcare staffing shortage is worldwide, the results of this paper are also useful internationally. The research was a qualitative case study and the research method used was group interview. Background data was gathered from the public media and healthcare trade organisations. The bottlenecks of talent management in hospital organisation seem to relate to retaining actions of senior personnel. Concurrently, the organisation should develop new practices for attracting new personnel. Very few efforts on image marketing and recruitment have been done. The Internet has not been fully exploited and recruitment information has not been sent even to the neighbouring nursing college. Job rotation has not been used as a help in recruitment and competence development. Difficulties exist in transmitting tacit knowledge from a retiring nurse to a junior nurse. Leadership skills of the superior seem to be important when retaining and committing senior personnel. Recruitment and retention problems encourage organisations to develop new recruitment and commitment practices as well as management and leadership skills.

  6. Attitudes towards care robots among Finnish home care personnel - a comparison of two approaches.

    Science.gov (United States)

    Rantanen, Teemu; Lehto, Paula; Vuorinen, Pertti; Coco, Kirsi

    2017-08-22

    The significance of care robotics has been highlighted in recent years. The article examines the adoption of care robots in home care settings, and in particular Finnish home care personnel's attitudes towards robots. The study compares the importance of the Negative Attitudes towards Robots Scale advanced by Nomura and specific positive attitudes related to the usefulness of care robots for different tasks in the home care. A cross-sectional study conducted by questionnaire. The research data were gathered from a survey of Finnish home care personnel (n = 200). Exploratory factor analysis, Pearson's correlation coefficient and linear regression analysis. The Negative Attitudes towards Robots Scale (NARS), by Nomura, with a specific behavioural intention scale based on Ajzen's theory of planned behaviour, and a measure of positive attitudes towards the usefulness of care robots for different tasks in home care and the promotion of independent living of older persons. The study shows that NARS helps to explain psychological resistance related to the introduction of care robots, although the scale is susceptible to cultural differences. Care personnel's behavioural intentions related to the introduction of robot applications are influenced also by the perception of the usefulness of care robots. The study is based only on a Finnish sample, and the response rate of the study was relatively small (18.2%), which limits the generalisability of the results. The study shows that the examination of home care personnel's attitudes towards robots is not justified to focus only on one aspect, but a better explanation is achieved by combining the perspectives of societal attitudes, attitudes related to psychological reactions and the practical care and promotion of the independent living of older people. © 2017 Nordic College of Caring Science.

  7. Finnish Nuclear Power Development - Experiences and Lessons Learned

    International Nuclear Information System (INIS)

    Kara, M.; Mattila, L.

    1996-01-01

    A small nation planning to make use of nuclear energy technology faces an important question: Is a nuclear energy programme just buying a rector and fuel from abroad? The Finnish experience says no. Making the best economic and technical choices depends on circumstances and good decisions can be based only on adequate research. Carrying out a successful nuclear energy programme demands high quality standards and, most importantly, nuclear safety is a national responsibility. Through training of personal and a deep understanding of the technology are necessary to meet these challenges. In Finland, comprehensive coverage of important scientific and technical aspects has been achieved economically by pooling the resources of all domestic parties having relevant expertise and by extensive international collaboration. (author)

  8. The mysterious Spotted Green Pigeon and its relation to the Dodo and its kindred.

    Science.gov (United States)

    Heupink, Tim H; van Grouw, Hein; Lambert, David M

    2014-07-16

    The closely related and extinct Dodo (Raphus cucullatus) and Rodrigues Solitaire (Pezophaps solitaria), both in the subfamily Raphinae, are members of a clade of morphologically very diverse pigeons. Genetic analyses have revealed that the Nicobar Pigeon (Caloenas nicobarica) is the closest living relative of these birds, thereby highlighting their ancestors' remarkable migration and morphological evolution. The Spotted Green Pigeon (Caloenas maculata) was described in 1783 and showed some similarities to the Nicobar Pigeon. Soon however the taxon fell into obscurity, as it was regarded as simply an abnormal form of the Nicobar Pigeon. The relationship between both taxa has occasionally been questioned, leading some ornithologists to suggest that the two may in fact be different taxa. Today only one of the original two specimens survives and nothing is known about the origin of the taxon. Due to its potential close relationship, the Spotted Green Pigeon may hold clues to the historical migration, isolation and morphological evolution of the Dodo and its kindred. We use ancient DNA methodologies to investigate the phylogeny and authenticity of the Spotted Green Pigeon. A novel extraction method with the ability to retain and purify heavily fragmented DNA is used to investigate two feathers from the sole surviving specimen. Maximum Likelihood phylogenetic analyses reveal that the Spotted Green Pigeon is a unique lineage and together with the Nicobar Pigeon, is basal to the Dodo and Rodrigues Solitaire. The distance observed for the Spotted Green Pigeon and Nicobar Pigeon is larger than that observed within other Pigeon species, indicating that the Spotted Green pigeon is a unique taxon, thereby also indicating it is a genuine addition to the list of extinct species. The phylogenetic placement of the Spotted Green Pigeon indicates that the ancestors of both Caloenas and therefore Raphinae displayed and shared the following traits: ability of flight, semi

  9. Two Finnish USH1B patients with three novel mutations in myosin VIIA.

    Science.gov (United States)

    Vastinsalo, Hanna; Isosomppi, Juha; Aittakorpi, Anne; Sankila, Eeva-Marja

    2006-09-21

    Usher syndrome (USH) is an autosomal recessive disorder resulting in retinal degeneration and sensorineural deafness caused by mutations in at least 10 gene loci. USH is divided into three main clinical types: USH1 (33-44%), USH2 (56-67%), and USH3. Worldwide, USH1 and USH2 account for most of the Usher syndrome cases with rare occurrence of USH3. In Finland, however, USH3 is the most common type (40%), explained by genetic and geographical isolation accompanied with a founder mutation, while USH1 is estimated to comprise 34% and USH2 12% of all USH cases. We examined two unrelated Finnish USH1 patients by sequencing. We found three new myosin VIIA (MYO7A) mutations: p.K923AfsX8, p.Q1896X, and p.E1349K. The p.K923AfsX8 mutation was present in both patients as well as in one of 200 Finnish control chromosomes. This is the first molecular genetic study of USH1 in Finland. We have found three new pathological mutations causing either premature termination of translation or replacement of an evolutionary conserved MYO7A amino acid.

  10. Antibody-based screening for hereditary nonpolyposis colorectal carcinoma compared with microsatellite analysis and sequencing

    DEFF Research Database (Denmark)

    Christensen, Mariann; Katballe, Niels; Wikman, Friedrik

    2002-01-01

    BACKGROUND: Germline mutations in the DNA mismatch repair genes, MSH2, MLH1, and others are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Due to the high costs of sequencing, cheaper screening methods are needed to identify HNPCC cases. Ideally, these methods should have a high...... carcinoma of whom 11 met the Amsterdam criteria and 31 were suspected to belong to HNPCC families. Thirty-five patients were examined by microsatellite analysis, 40 by immunohistochemical staining, and in 31 patients both the MLH1 and MSH2 genes were sequenced. RESULTS: Ninety-two percent of patients...... the three methods was found in 74 % of the tumors. CONCLUSIONS: The authors suggest that immunohistochemistry should be used in combination with microsatellite analysis to prescreen suspected HNPCC patients for the selection of cases where sequencing of the MLH1 and MSH2 mismatch repair genes is indicated....

  11. Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

    Directory of Open Access Journals (Sweden)

    D. Speake

    2011-01-01

    Full Text Available Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI of sporadic, HNPCC, and familial hyperplastic polyps (HPs. Methods. Methylation-specific PCR (MSP and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistry assessed Ki67, CK20, hMLH-1, hMSH-2, and hMSH-6 protein expression. MSI analysis was performed on those polyps with adequate DNA remaining. Results. 124 HPs were identified 78 sporadic, 21 HNPCC, 25 familial, and the HNPCC group demonstrated no significant differences in overall methylation (P=.186 Chi2. The familial group demonstrated significantly less over all methylation levels (P=.004 Chi2. Conclusions. HPs that occur in HNPCC have no more worrying features at a molecular level than those patients with HPs in a sporadic setting.

  12. Towards Strategic Actorhood? The Execution of Institutional Positioning Strategies at Finnish Universities of Applied Sciences

    Science.gov (United States)

    Vuori, Johanna

    2016-01-01

    Given the emerging interest in institutional positioning and to augment the small number of empirical studies in this field, this paper presents discussion about how Finnish universities of applied sciences implement their profiling strategies. The analysis is based on an examination of documents recently submitted by these institutions when…

  13. Marketing communication strategy of Finnish and Japanese mobile game developers and publishers

    OpenAIRE

    Cheng, Yi-Tung

    2017-01-01

    Both the marketing communication strategy of mobile game industry and the industry itself have been drastically evolving in the past years since the development of computation, data transfer and communication technology on mobile devices. Marketing communication has been considered a significant part in marketing strategy, but the marketing communication strategy, activity and channels were not well investigated so far. In this study, 9 SMEs Finnish and Japanese mobile game developers and pub...

  14. Hereditary non-polyposis colorectal cancer : Identification of mutation carriers and assessing pathogenicity of mutations

    NARCIS (Netherlands)

    Niessen, RC; Sijmons, RH; Berends, MJW; Ou, J; Hofstra, RNW; Kleibeuker, JH

    2004-01-01

    Hereditary non-polyposis colorectal cancer (HNPCC), also referred to as Lynch syndrome, is an autosomal dominantly inherited disorder that is characterized by susceptibility to colorectal cancer and extracolonic malignancies, in particular endometrial cancer. HNPCC is caused by pathogenic mutations

  15. Nuclear is coming back in Finland. The finnish deputies approved the design of a new reactor

    International Nuclear Information System (INIS)

    Canton, Ch.

    2002-01-01

    The finnish Parliament agreed the construction of a fifth reactor in the country to reach an increase of 25% of its electric power consumption in 2015. The government decision and the impacts on the european nuclear industry are analyzed. (A.L.B.)

  16. Received and needed social support at the workplace in Norwegian and Finnish stage 1 breast cancer survivors: a study from the Nordic Study Group of Cancer and Work (NOCWO).

    Science.gov (United States)

    Gudbergsson, Saevar B; Fosså, Sophie D; Lindbohm, Marja-Liisa; Dahl, Alv A

    2009-01-01

    Cross-cultural studies of comparable patients can identify differences of health care services and point to issues of possible improvement. In this cross-sectional study we compared self-reported received and needed social support at the workplace of disease-free breast cancer survivors (BCSs) stage I from Norway and Finland. Age-matched samples of 135 BCSs from Norway and 148 from Finland were examined using a questionnaire including socio-demographic factors, employment data, measurements of social support at work from supervisors, colleagues and the occupational health service (OHS), and several other measurements. Finnish BCSs had significantly higher education and a higher rate of full-time employment than Norwegian ones. With adjustment for education and work time, Finnish compared to Norwegian BCSs reported significantly less received social support from supervisors, while they received significantly more social support from OHS. No differences were observed in received support from colleagues between Finnish and Norwegian BCSs. Somatic health was most strongly associated with received and needed support from supervisors, colleagues and OHS. The differences in received and needed social support at work observed between Norwegian and Finnish BCSs treated for stage I disease challenge strengthening of OHS for Norwegian BCSs and increased attention by supervisors in Finnish BCSs.

  17. Exposure of Finnish population to ultraviolet radiation and radiation measurements

    International Nuclear Information System (INIS)

    Hoikkala, M.; Lappalainen, J.; Leszczynski, K.; Paile, W.

    1990-01-01

    This report is based on a survey of the literature on radiation risks involved in sunbathing and the use of solaria. The purpose of the report is to provide background information for the development of regulations on solaria and for informing the public about the risks posed by solaria and the sun. The report gives an overview of the properties and biological effects of ultraviolet radiation. The most important regulations and recommendations issued in various countries are presented. The connection between ultraviolet radiation and the risks of skin cancer is examined both on a general level and in reference to information obtained from the Finnish Cancer Registry. In Finland, the incidence of melanomas nearly tripled between 1960 and 1980. The most important cause is considered to be the population's increased exposure to the su's ultraviolet radiation. There are no reliable data on the connection between the use of solaria and the risks of skin cancer. It is estimated, however, that solaria account for less than 10 per cent of the skin cancer risk of the whole population. There are some difficult physical problems associated with the measurement of ultraviolet radiation emitted by both natural sources and solaria. A preliminary study of these problems has been undertaken by means of a survey of the available literature, supplemented by a review of measurements performed by the Finnish Centre For Radiation and Nuclear Safety. The estimated inaccuracy of the Optronic 742 spectroradiometer used by the Centre in the measurement of ultraviolet radiation emitted by the sun and solaria is about +-14%

  18. Search for intracranial aneurysm susceptibility gene(s using Finnish families

    Directory of Open Access Journals (Sweden)

    Ryynänen Markku

    2002-08-01

    Full Text Available Abstract Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial aneurysms (IA. Epidemiological evidence suggests that IAs cluster in families, and are therefore probably genetic. Identification of individuals at risk for developing IAs by genetic tests will allow concentration of diagnostic imaging on high-risk individuals. We used model-free linkage analysis based on allele sharing with a two-stage design for a genome-wide scan to identify chromosomal regions that may harbor IA loci. Methods We previously estimated sibling relative risk in the Finnish population at between 9 and 16, and proceeded with a genome-wide scan for loci predisposing to IA. In 85 Finnish families with two or more affected members, 48 affected sibling pairs (ASPs were available for our genetic study. Power calculations indicated that 48 ASPs were adequate to identify chromosomal regions likely to harbor predisposing genes and that a liberal stage I lod score threshold of 0.8 provided a reasonable balance between detection of false positive regions and failure to detect real loci with moderate effect. Results Seven chromosomal regions exceeded the stage I lod score threshold of 0.8 and five exceeded 1.0. The most significant region, on chromosome 19q, had a maximum multipoint lod score (MLS of 2.6. Conclusions Our study provides evidence for the locations of genes predisposing to IA. Further studies are necessary to elucidate the genes and their role in the pathophysiology of IA, and to design genetic tests.

  19. Ecommerce drivers and marketing partnerships in successful export marketing of Finnish born globals

    OpenAIRE

    Penttinen, Jukka

    2015-01-01

    This study examines the utilization of ecommerce and marketing partnerships as part of born global internationalization strategies. The study will combine the existing literature of born global internationalization, export marketing strategies and ecommerce as part of internationalization to form an understanding on how two Finnish health and welfare sector born globals internationalize, and how ecommerce drivers affect their internationalization. Because of the explorative nature of the stud...

  20. Finnish Research Programme on Nuclear Waste Management (KYT). Framework Programme for 2002-2005

    International Nuclear Information System (INIS)

    Rasilainen, K.

    2002-12-01

    The new Finnish research programme on nuclear waste management (KYT) will be conducted in 2002 - 2005. This framework programme describes the starting point, the basic aims and the organisation of the research programme. The starting point of the KYT programme is derived from the present state and future challenges of Finnish nuclear waste management. The research programme is funded mainly by the Ministry of Trade and Industry (KTM), the Radiation and Nuclear Safety Authority (STUK), Posiva Oy, Fortum Oyj, Teollisuuden Voima Oy (TVO), and the National Technology Agency (Tekes). As both regulators and implementors are involved, the research programme concentrates on neutral research topics that must be studied in any case. Methods and tools for experimental and theoretical studies fall in this category. State of the art -reviews on relevant topics also create national know-how. Topics that directly belong to licensing activities of nuclear waste management are excluded from the research programme. KYT carries out technical studies that increase national know-how in the area of nuclear waste management. The aim is to maintain and develop basic expertise needed in the operations derived from the national nuclear waste management plan. The studies have been divided into strategic studies and studies enhancing the long-term safety of spent nuclear fuel disposal. Strategic studies support the overall feasibility of Finnish nuclear waste management. These studies include basic options and overall safety principles related to nuclear fuel cycle and nuclear waste management. In addition, general cost estimates as well as general safety considerations related to transportations, low- and medium level wastes, and decommissioning are included in strategic studies. Studies supporting the long-term safety of spent fuel disposal include issues related to performance assessment methodology, release of radionuclides from the repository, behaviour of bedrock and groundwater

  1. Awareness of endometrial cancer risk and compliance with screening in hereditary nonpolyposis colorectal cancer

    DEFF Research Database (Denmark)

    Ketabi, Zohreh; Mosgaard, Berit J; Gerdes, Anne-Marie

    2012-01-01

    Women with hereditary nonpolyposis colorectal cancer (HNPCC) have a 40-60% lifetime risk for endometrial cancer. Guidelines in Denmark recommend gynecologic screening for female members of families with HNPCC. We estimated the knowledge of endometrial cancer risk and identified possible predictors...

  2. Digitalization of music and Long Tail effect in Finnish music industry

    OpenAIRE

    Peltola, Juuso

    2017-01-01

    In this thesis the existence of Long Tail effect in Finnish music industry is studied. The Long Tail effect is defined as the expansion of music supply to include a higher number of niche products instead of focusing on fewer ‘superstar’ hits. Emergency of ‘superstar’ hits has been the trend in entertainment industry since the invention of mass media and music recording, but new technological innovations can start to challenge it. The source of the Long Tail effect is in newer technological i...

  3. The Influence of Performance-Based Management on Teaching and Research Performance of Finnish Senior Academics

    Science.gov (United States)

    Kivistö, Jussi; Pekkola, Elias; Lyytinen, Anu

    2017-01-01

    Despite the widespread use of performance-based management in higher education, empirical research on its actual impact has remained scarce, particularly in Europe. With agency theory as a framework, our study utilised survey data collected from Finnish universities in order to explore the influence of performance management on perceived teaching…

  4. Cultural Differences in the Health Information Environments and Practices between Finnish and Japanese University Students

    Science.gov (United States)

    Askola, Kreetta; Atsushi, Toshimori; Huotari, Maija-Leena

    2010-01-01

    Introduction: The aim of this study was to identify cultural differences in the information environment and information practices, namely active seeking and encountering, of web-based health information between Finnish and Japanese university students. Method: The data were gathered with a Web-based survey among first-year university students at…

  5. Ordinance on the Finnish Centre of Radiation and Nuclear Safety

    International Nuclear Information System (INIS)

    1990-01-01

    This Ordinance was adopted in implementation of the 1983 Act setting up the Finnish Centre for Radiation and Nuclear Safety and the 1987 Nuclear Energy Act and entered into force on 1 November 1990. The Ordinance specifies the tasks of the Centre, as provided under both Acts, and gives it several supplementary responsibilities. In addition to its overall competence in respect of radiation safety, the Centre will carry out research into and supervise the health effects of radiation and maintain a laboratory for national measurements in that field. The Ordinance also sets out the Centre's organisation chart and the staff duties [fr

  6. Email medication counseling services provided by Finnish community pharmacies.

    Science.gov (United States)

    Pohjanoksa-Mäntylä, Marika K; Kulovaara, Heidi; Bell, J Simon; Enäkoski, Marianne; Airaksinen, Marja S

    2008-12-01

    The importance of email as a mode of communication between medication users and pharmacists is likely to increase. However, little is known about the email medication counseling practices of community pharmacies. To determine the prevalence of email medication counseling services in Finland and to assess the accuracy and comprehensiveness of responses by pharmacies providing the opportunity for email medication counseling to inquiries related to use of antidepressants. An inventory was made of all Finnish community pharmacies that provided the opportunity for email medication counseling. Data related to the accuracy and comprehensiveness of responses were collected, using a virtual pseudo-customer method with 3 scenarios related to common concerns of patients on antidepressants. Two inquiries were emailed to each pharmacy that provided the opportunity for email medication counseling in January and February 2005. The responses were content analyzed by 2 researchers, using a prestructured scoring system. Almost one-third (30%, n = 182) of Finnish community pharmacies maintained a working Web site, and 94% of those provided the opportunity for email medication counseling. An online "ask-the-pharmacist" service was offered by 13% (n = 23) of the pharmacies with a Web site. Pharmacies responded to 54% of the email inquiries sent by the virtual pseudo-customers. The response rate and the content score ratio between mean and maximum scores varied among the scenarios. The content score ratio was highest for the scenarios concerning the adverse effects of fluoxetine (0.53, n = 55) and interactions with mirtazapine (0.52, n = 63) and lowest for the scenario related to sexual dysfunction and weight gain associated with citalopram (0.38, n = 52). Community pharmacies are potential providers of email medication counseling services. However, more attention should be directed to responding to consumer inquiries and to the content of these responses.

  7. Plans for an on-line computer at the Finnish TRIGA Laboratory

    International Nuclear Information System (INIS)

    Junttila, J.; Tamminen, A.; Palmgren, A.

    1970-01-01

    Full text: The future plans at the Helsinki Triga reactor include an on-line computer system. The project is in its pre-planning stage, and if the financing can be arranged, the instancing is preliminarily scheduled to start in 1972. We estimate the probability of getting a computer to be 90%. The tasks of the system would be the monitoring and control of reactor power level and other operating conditions, and, on the other hand, data acquisition, analysis and apparatus control in different reactor laboratory experiments. These include the neutron diffractometer, the cold neutron facility and neutron TOF-measurements, gamma-spectroscopy, reactor noise measurements, and neutron activation analysis. It is our intention to purchase a medium-sized computer which is presently being developed by the Finnish company Oy Stroemberg Ab. This computer has been constructed by using the time sharing principle. Consequently, background jobs like testing of new programs, off-line calculations etc., can be executed simultaneously with the actual data taking and control operations. The interfering of programs with each other is prevented by dividing the programs in protected segments. Different kinds of devices and functions can be added to the basic control processing unit, e.g. an automatic interrupt unit with up to 128 priority levels, a fast floating point arithmetic unit, and the control of a direct memory access channel. An additional fact, which makes this particular computer attractive to us, is that we wish to have the manufacturer's support in designing our special applications. The initial system cost of about 120.000 US$ is considered justified for three reasons of about equal importance: 1. The operation and utilization of our reactor will become more efficient. 2. All people involved in the project will learn how to handle a rather complicated-computerization project. 3. The Finnish Government can support the development of this computer by ordering one or two

  8. Nonindustrial private forest owners' opinions to and awareness of energy wood market and forest-based bioenergy certification. Results of a case study from Finnish Karelia

    Energy Technology Data Exchange (ETDEWEB)

    Halder, Pradipta; Mei, Qu; Pelkonen, Paavo [Eastern Finland Univ., Joensuu (Finland). School of Forest Sciences; Weckroth, Timo

    2012-12-01

    Nonindustrial private forest owners (NIPFs) in Finland are important stakeholders of forest management and roundwood supply decisions. Their role will also be significant to supply energy wood to meet Finland's target for renewable energy in the future. The main objectives of this study were to explore the opinions and awareness of the Finnish NIPFs related to the energy wood market and forest-based bioenergy certification issues in Finland and their relevance for future bioenergy policies. A questionnaire-based survey was conducted among NIPFs in Finnish Karelia (N = 79). NIPFs considered price as the main deciding factor in harvesting and selling of energy wood. The present low price of energy wood compared to pulpwood did not motivate them to increase harvesting and selling of energy wood. The NIPFs appeared to be unaware of the forest-based bioenergy certification. However, they expected that such certification schemes would be easy to follow, develop energy wood market, and promote environmentally sound forest management practices in Finland. Private forest owners' associations and personal information letters emerged as the most favored means to disseminate information on forest-based bioenergy certification to the Finnish NIPFs. The study explored the opinions and awareness of the Finnish NIPFs related to energy wood market and forest based bioenergy certification from Finnish Karelia. The conclusions derived from the study might be highly policy-relevant concerning the development of energy wood market and related certification schemes. Future studies should include larger sample size for increasing the representativeness of the findings. (orig.)

  9. Reliability of diesel generators at the Finnish and Swedish nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Pulkkinen, Urho [Technical Research Centre of Finland, Vuorimiehentie 5, SF-02150, Espoo (Finland)

    1986-02-15

    The operating experiences of 40 stand-by diesel generators at the Finnish and Swedish nuclear power plants have been analysed with special emphasis on the impact of the frequency of surveillance testing and of the test procedure on diesel generator reliability, the contribution of design, manufacturing, testing and maintenance errors and the potential and actual common cause failures, The results pf the analyses consisted both practical recommendations and mathematical reliability models and useful reliability data. (author)

  10. Environmental Factors and Colorectal Tumor Risk in Individuals With Hereditary Nonpolyposis Colorectal Cancer

    NARCIS (Netherlands)

    Diergaarde, B.; Braam, H.; Vasen, H.F.; Nagengast, F.M.; Muijen, van G.N.P.; Kok, F.J.; Kampman, E.

    2007-01-01

    Background & Aims: Individuals with hereditary nonpolyposis colorectal cancer (HNPCC) are at increased risk for colorectal cancer. Environmental factors might play a role in HNPCC-associated carcinogenesis. The aim of this study was to gain insight into the effects of environmental factors on

  11. Heredity nonpolyposis colorectal cancer : studies on tumor development and preventive strategies

    NARCIS (Netherlands)

    Rijcken, Fleur Elise Marie

    2006-01-01

    HNPCC is een relatief vaak voorkomend erfelijk kankersyndroom. Fleur Rijcken onderzocht de ontstaanswijze van de twee meest voorkomende HNPCC-tumoren, dikkedarm- en baarmoederkanker. Zij toonde aan dat de voorlopers van darmkanker, de dysplastische poliepen, vooral in het rechter deel van de darm

  12. Sulindac treatment in hereditary non-pollyposis colorectal cancer

    NARCIS (Netherlands)

    Rijcken, Fleur E. M.; Hollema, Harry; van der Zee, Ate G. J.; van der Sluis, Tineke; Ek, Wytske Boersma-van; Kleibeuker, Jan H.

    Non-steroidal anti-inflammatory drugs, e.g. sulindac have been extensively studied for chemoprevention in familial adenomatous polyposis, but not in hereditary non-polyposis colorectal cancer (HNPCC). We evaluated these effects in HNPCC using surrogate end-points for cancer risk. In a randomised

  13. The impacts of climate change on the Finnish economy

    Energy Technology Data Exchange (ETDEWEB)

    Kuoppamaeki, P [Research Inst. of the Finnish Economy, Helsinki (Finland)

    1997-12-31

    The purpose of the project was to evaluate the potential influence of global warming on the Finnish economy and well-being during the next 50 to 100 years. In order to achieve this goal a cost-benefit analysis was conducted which produced a quantitative estimate of the economic and partially non-economic effects of the climate change projected to happen in Finland. The analysis utilised the natural scientific evidence produced by other SILMU projects in partial sector models. Also a broader view of the phenomena and the possibilities for restricting greenhouse gas emissions was briefly discussed and surveyed. Two of the more important side-goals were to develop the methodology for country analysis and study the possibilities for adaptation

  14. The impacts of climate change on the Finnish economy

    Energy Technology Data Exchange (ETDEWEB)

    Kuoppamaeki, P. [Research Inst. of the Finnish Economy, Helsinki (Finland)

    1996-12-31

    The purpose of the project was to evaluate the potential influence of global warming on the Finnish economy and well-being during the next 50 to 100 years. In order to achieve this goal a cost-benefit analysis was conducted which produced a quantitative estimate of the economic and partially non-economic effects of the climate change projected to happen in Finland. The analysis utilised the natural scientific evidence produced by other SILMU projects in partial sector models. Also a broader view of the phenomena and the possibilities for restricting greenhouse gas emissions was briefly discussed and surveyed. Two of the more important side-goals were to develop the methodology for country analysis and study the possibilities for adaptation

  15. Even the Best Have Difficulties: A Study of Finnish Straight-A Graduates' Resource-Oriented Solutions

    Science.gov (United States)

    Salmela, Mari; Määttä, Kaarina

    2015-01-01

    To achieve top scores, students need not only talents and study skills but also they have to conquer various adversities successfully. This research focused on the study paths, the concept adopted from Hickman, Bartholomew, Mathwig, and Heinrich (2008), of Finnish straight-A graduates in general upper secondary education. In this article, we refer…

  16. Trust in Management under Post-bureaucratic Conditions: The Case of Finnish Civil Servants

    OpenAIRE

    Jaakko Koivumäki; Pasi Pyöriä

    2013-01-01

    The Finnish state administration has recently undergone a wave of reforms towards decentralized decision-making and increased flexibility in organizing work. Traditional bureaucracy, however, has its virtues. Based on a survey and qualitative interview material, the results presented in this paper indicate that many characteristics of bureaucracy, such as well-defined work roles and hierarchical control, facilitate trust among employees. In contrast, the current post-bureaucratic model of org...

  17. Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort

    Science.gov (United States)

    Lampi, Katja M.; Hinkka-Yli-Salomäki, Susanna; Lehti, Venla; Helenius, Hans; Gissler, Mika; Brown, Alan S.; Sourander, Andre

    2013-01-01

    Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger's syndrome (n = 1,785) or other pervasive…

  18. Factors effecting Corporate Social Responsibility disclosure ratings:an empirical study of Finnish listed companies

    OpenAIRE

    Roitto, A. (Artturi)

    2013-01-01

    Abstract As Corporate Social Responsibility (CSR) disclosure is becoming more common practise amongst companies, it is valuable to understand the underlying factors involved. The Goal of this thesis is to examine if the factors suggested by previous studies seem to have significance in a Finnish sample composed of 31 listed companies. As an ancillary research question linkage between Corporate Governance recommendation devi...

  19. Tobacco, cannabis, and other illicit drug use among Finnish adolescent twins: causal relationship or correlated liabilities?

    NARCIS (Netherlands)

    Huizink, A.C.; Levälahti, E.; Korhonen, T.; Dick, D.M.; Pulkkinen, L.; Rose, R.J.; Kaprio, J.

    2010-01-01

    Objective: Among Finnish adolescent twins, we compared (a) a model that describes a direct impact of liability to tobacco use on cannabis and other illicit drug use with (b) a model that included a shared underlying liability for these substances. Furthermore, the extent to which genetic and

  20. Fate of the herbicides glyphosate, glufosinate-ammonium, phenmedipham, ethofumesate and metamitron in two Finnish arable soils.

    Science.gov (United States)

    Laitinen, Pirkko; Siimes, Katri; Eronen, Liisa; Rämö, Sari; Welling, Leena; Oinonen, Seija; Mattsoff, Leona; Ruohonen-Lehto, Marja

    2006-06-01

    The fate of five herbicides (glyphosate, glufosinate-ammonium, phenmedipham, ethofumesate and metamitron) was studied in two Finnish sugar beet fields for 26 months. Soil types were sandy loam and clay. Two different herbicide-tolerant sugar beet cultivars and three different herbicide application schedules were used. Meteorological data were collected throughout the study and soil properties were thoroughly analysed. An extensive data set of herbicide residue concentrations in soil was collected. Five different soil depths were sampled. The study was carried out using common Finnish agricultural practices and represents typical sugar beet cultivation conditions in Finland. The overall observed order of persistence was ethofumesate > glyphosate > phenmedipham > metamitron > glufosinate-ammonium. Only ethofumesate and glyphosate persisted until the subsequent spring. Seasonal variation in herbicide dissipation was very high and dissipation ceased almost completely during winter. During the 2 year experiment no indication of potential groundwater pollution risk was obtained, but herbicides may cause surface water pollution. Copyright (c) 2006 Society of Chemical Industry

  1. Operation of Finnish nuclear power plants. Quarterly report, 2nd quarter 1997

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1997-12-01

    Quarterly Reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety which STUK - Radiation and Nuclear Safety Authority considers safety significant. Safety improvements at the plants are also described. The Report also includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants' production and load factors. The Finnish nuclear power plant units were in power operation in the second quarter of 1997, except for the annual maintenance outages of Olkiluoto plant units and the Midsummer outage at Olkiluoto 2 due to reduced demand for electricity. There were also brief interruptions in power operation at the Olkiluoto plant units due to three reactor scrams. All plant units are undergoing long-term test operation at upgraded reactor power level which has been approved by STUK The load factor average of all plant units was 88.7 %. One event in the second quarter of 1997 was classified level 1 on the INES. The event in question was a scram at Olkiluoto 1 which was caused by erroneous opening of switches. Other events in this quarter were level 0. Occupational doses and radioactive releases off-site were below authorized limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.)

  2. Lack of Commitment? Work Orientations of Finnish Employees in a European Comparison

    Directory of Open Access Journals (Sweden)

    Teemu Turunen

    2014-05-01

    Full Text Available It has been argued that individuals’ employment commitment, that is, their commitment to work in general is crucial in today’s labor markets where life-long employment relationships are less frequently offered by organizations. In addition, employees’ organizational commitment, that is, their commitment to their own organization is also vital for organizations and firms, affecting many areas of importance to them. This article asks how Finnish employees rank in both employment commitment and affective organizational commitment compared with employees in 15 other European countries. The data were collected in 2005–2007 through the International Social Survey Program (ISSP, Work Orientation Module III. The results show Finnish employees scoring below European averages in both types of commitment when employee-level and organizationlevel factors are taken into account. Employment commitment was highest in Norway and affective organizational commitment highest in Portugal. The perceived intrinsic rewards of the job were the strongest predictor of employment and affective organizational commitment in most of the countries researched, increasing both these types of commitment. However, the perceived social relations between management and employees were found to be the most powerful determinant of affective organizational commitment in Finland, with perceived good relations adding to the affective organizational commitment of employees. The data were analyzed mainly by means of a general linear model procedure.

  3. Auditor recommendations resulting from three clinical audit rounds in Finnish radiology units.

    Science.gov (United States)

    Miettunen, Kirsi; Metsälä, Eija

    2017-06-01

    Background The purpose of clinical audits performed in radiology units is to reduce the radiation dose of patients and staff and to implement evidence-based best practices. Purpose To describe auditor recommendations in three Finnish clinical audit rounds performed in 2002-2014, and to determine if auditor recommendations have had any impact on improving medical imaging practice. Material and Methods The retrospective observational study was performed in radiology units holding a radiation safety license issued by the Finnish Radiation and Nuclear Safety Authority. The data comprised a systematic sample (n = 120) of auditor reports produced in three auditing rounds in these units during the years 2002-2014. The data were analyzed by descriptive methods and by using the Friedman two-way ANOVA test. Results The number of auditor recommendations given varied between clinical audit rounds and according to the type of imaging unit, as well as according to calculation method. Proportionally, the most recommendations in all three clinical audit rounds were given about defining and using quality assurance functions and about guidelines and practices for carrying out procedures involving radiation exposure. Demanding radiology units improved their practices more than basic imaging units towards the third round. Conclusion Auditor recommendations help to address the deficiencies in imaging practices. There is a need to develop uniform guidelines and to provide tutoring for clinical auditors in order to produce comparable clinical audit results.

  4. Interest in energy wood and energy crop production among Finnish non-industrial private forest owners

    International Nuclear Information System (INIS)

    Raemoe, A.-K.; Jaervinen, E.; Latvala, T.; Toivonen, R.; Silvennoinen, H.

    2009-01-01

    EU targets and regulations regarding energy production and the reduction of greenhouse gas emissions have been tightening in the 2000s. In Finland the targets are planned to be achieved mainly by increasing the use of biomass. Wood already accounts for a marked proportion of Finnish energy production, but additional reserves are still available. Energy crop production also has considerable potential. Practically all Finnish farmers are also forest owners. Therefore, private forest owners are in a decisive position regarding the supply of energy wood and crops in Finland. In this paper the future supply of biomass is examined according to their past behaviour, intentions and attitudes. Finnish forest owners have a positive attitude towards the use of wood and crops in energy production. Price is becoming more critical as a motive for the supply of energy wood. Recreation and nature conservation play a smaller role than factors related to wood production and forest management as for motives for harvesting energy wood. However, almost a half of forest owners in this study were uncertain of their willingness to supply biomass. This is partly due to limited knowledge of the issues involved in energy wood and agricultural energy crop production and the underdeveloped markets for energy biomass. In order to achieve the targets, supply should be activated by further developing market practices, information, guidance and possibly other incentives for landowners. In general, there is interest among landowners in increasing the supply of energy biomass. However, the growth of supply presumes that production is an economically attractive and competitive alternative, that the markets are better organized than at present, and that more comprehensive information is available about bioenergy and biomass markets and production techniques.

  5. Linkage of morbid obesity with polymorphic microsatellite markers on chromosome 1q31 in a three-generation Canadian kindred

    Energy Technology Data Exchange (ETDEWEB)

    Murray, J.D.; Bulman, D.E.; Ebers, G.C. [University Hospital, London (Canada)]|[INSERM, Paris (France)] [and others

    1994-09-01

    Obesity is the most common nutritional disorder affecting Western societies. An estimated 3.7 million Canadians are considered to be overweight, a condition associated with hypertension, accelerated atherosclerosis, diabetes and a host of other medical problems. We have identified a 3 generation kindred in which morbid obesity appears to segregate in an autosomal dominant manner. All individuals were examined. Mass (kg) and heights (m) were measured in order to determine a body mass index (BMI) for each individual. Those individuals with BMI of greater than or equal to 30.0 were designated as affected. In the pedigree studied 25 individuals met this criteria and 12 of these were morbidly obese (BMI greater or equal to 40.0). A search of candidate genes proved unfruitful. A linkage study was initiated. All individuals in the pedigree were genotyped for microsatellite markers which were spaced every 20 centimorgans (cM). Positive evidence of linkage was detected with markers which map to 1q31-32 (lod score of 3.6 at {theta} = 0.05). Notably, strong effects for fatness in pigs have been found on pig chromosome 4 which has synteny with human chromosome 1q21-32. We are currently attempting to refine the position of this gene using linkage analysis with other microsatellite markers from this region of the genome. In addition we are screening other families in which obesity segregates for linkage to 1q31.

  6. Simulation of concrete deterioration in Finnish rock cavern conditions for final disposal of nuclear waste

    International Nuclear Information System (INIS)

    Kari, O.P.; Puttonen, J.

    2014-01-01

    Highlights: • Concrete deterioration in Finnish rock cavern disposal conditions was simulated. • Simulation requires advanced models instead of traditional linear diffusion models. • Concrete analysed performed moderately during the period of 500 years. • Corrosion of steel reinforcement cannot be excluded during the period analysed. - Abstract: A simulation of concrete ageing in Finnish rock cavern disposal conditions showed that the concrete undergoes complex deterioration processes during the period required for lowering the level of radiation. In respect of the concrete ageing, the life time of the disposal facilities shall be divided into the periods before and after the closing of the caverns. Generally, the sulphate-resistant type of concrete analysed performed moderately during the analysed period of 500 years contrary to the corrosion of steel reinforcement, which cannot be excluded. Simulation of ageing clearly requires thermodynamical methods instead of linear diffusion models based on Fick’s law, which are traditionally used in construction industry. The study proves that the thermodynamical simulation method developed with adequate experimental data also makes it possible to observe latent factors of concrete deterioration

  7. Operation of Finnish nuclear power plants. Quarterly report 4th quarter, 1994 and annual summary

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1995-05-01

    The Loviisa NPP units were in power operation the whole last quarter, with the exception of a reactor scram at Loviisa 1. The load factor average of all Finnish plant units was 100.2 %. The annual average was 90.0 %. All events in the fourth annual quarter were assigned level 0 (no safety significance) on the international INES scale. Four events in 1994 were classified level 1 (an anomaly). The Finnish Centre for Radiation and Nuclear Safety in December approved Imatran Voima Oy's application to extend the operation of the reactor pressure vessel of Loviisa 2 until the annual maintenance outage of 2010. During this quarter, a batch of spent fuel from Loviisa power plant was transported to Russia. Occupational doses and radioactive releases off-site were below authorised limits. Only such quantities of plant-based radioactive materials were measurable in samples collected around the plants as have no bearing on the radiation exposure of the population. The report includes a summary of all the items described in the Quarterly Reports of 1994. (8 figs., 4 tabs.)

  8. Operation of Finnish nuclear power plants. Quarterly report 4th quarter, 1994 and annual summary

    Energy Technology Data Exchange (ETDEWEB)

    Tossavainen, K [ed.

    1995-05-01

    The Loviisa NPP units were in power operation the whole last quarter, with the exception of a reactor scram at Loviisa 1. The load factor average of all Finnish plant units was 100.2 %. The annual average was 90.0 %. All events in the fourth annual quarter were assigned level 0 (no safety significance) on the international INES scale. Four events in 1994 were classified level 1 (an anomaly). The Finnish Centre for Radiation and Nuclear Safety in December approved Imatran Voima Oy`s application to extend the operation of the reactor pressure vessel of Loviisa 2 until the annual maintenance outage of 2010. During this quarter, a batch of spent fuel from Loviisa power plant was transported to Russia. Occupational doses and radioactive releases off-site were below authorised limits. Only such quantities of plant-based radioactive materials were measurable in samples collected around the plants as have no bearing on the radiation exposure of the population. The report includes a summary of all the items described in the Quarterly Reports of 1994. (8 figs., 4 tabs.).

  9. Does a "one-stop" gynecology screening clinic for women in hereditary nonpolyposis colorectal cancer families have an impact on their psychological morbidity and perception of health?

    Science.gov (United States)

    Wood, N J; Munot, S; Sheridan, E; Duffy, S R

    2008-01-01

    Screening programs can reduce the burden of disease, however, they can be associated with raised levels of anxiety. The risk of endometrial and ovarian cancer is increased in hereditary nonpolyposis colorectal cancer (HNPCC). There is no prospective evidence to support screening for gynecological disease in HNPCC, however, current recommendations include the use of ultrasound and endometrial biopsy. This study assesses the impact of screening for gynecological cancer on self-reported symptoms of anxiety, depression, and perceptions of health. Women from HNPCC families attending gynecological screening (n = 26) completed the Hospital Anxiety and Depression Scale and the ShortForm36v2 questionnaires prior to screening with transvaginal ultrasound, outpatient/office hysteroscopy, endometrial biopsy, and ovarian tumor marker assessment (CA125). The same questionnaires were completed at 3 and 6 months following screening (15/26). Women in HNPCC families attending for gynecological screening did not have excess symptoms of anxiety or depression at baseline in subjective comparison to other populations. The process of screening and false positive screening results had no significant impact on symptoms of anxiety and depression or perceptions of health. We conclude that within the limitations of analysis in this small study group, screening for gynecological disease in HNPCC does not appear to be associated with any psychological morbidity.

  10. Genetic variances, trends and mode of inheritance for hip and elbow dysplasia in Finnish dog populations

    NARCIS (Netherlands)

    Mäki, K.; Groen, A.F.; Liinamo, A.E.; Ojala, M.

    2002-01-01

    The aims of this study were to assess genetic variances, trends and mode of inheritance for hip and elbow dysplasia in Finnish dog populations. The influence of time-dependent fixed effects in the model when estimating the genetic trends was also studied. Official hip and elbow dysplasia screening

  11. New nuclear power plant unit in Finland accepted by the Finnish Parliament

    International Nuclear Information System (INIS)

    Kaetkae, M.

    2002-01-01

    The nuclear option has been included in Finland's energy strategy since late 1990's. Based on TVO's application the Finnish Parliament accepted in May 2002 the decision in principle to build a new nuclear power plant unit. The main arguments were the growth of electricity demand, reduction of CO 2 emissions, security of energy supply and reasonable as well as predictable electricity price. TVO's intention is to get the new power plant unit into commercial operation at the end of this decade.(author)

  12. A national collaboration process: Finnish engineering education for the benefit of people and environment.

    Science.gov (United States)

    Takala, A; Korhonen-Yrjänheikki, K

    2013-12-01

    The key stakeholders of the Finnish engineering education collaborated during 2006-09 to reform the system of education, to face the challenges of the changing business environment and to create a national strategy for the Finnish engineering education. The work process was carried out using participatory work methods. Impacts of sustainable development (SD) on engineering education were analysed in one of the subprojects. In addition to participatory workshops, the core part of the work on SD consisted of a research with more than 60 interviews and an extensive literature survey. This paper discusses the results of the research and the work process of the Collaboration Group in the subproject of SD. It is suggested that enhancing systematic dialogue among key stakeholders using participatory work methods is crucial in increasing motivation and commitment in incorporating SD in engineering education. Development of the context of learning is essential for improving skills of engineering graduates in some of the key abilities related to SD: systemic- and life-cycle thinking, ethical understanding, collaborative learning and critical reflection skills. This requires changing of the educational paradigm from teacher-centred to learner-centred applying problem- and project-oriented active learning methods.

  13. On geomagnetically-induced currents in the Finnish 400 kV power system by an auroral electrojet current

    International Nuclear Information System (INIS)

    Pirjola, R.; Viljanen, A.

    1989-01-01

    The auroral electrojet current flowing in the ionosphere is modeled by a horizontal east-west line current of infinite length. The earth is described by a simple two-layer model. An expression for the earth-surface electric field, which is thus connected with a geomagnetic disturbance in and near the auroral zone, is given. This electric field is considered as external from the viewpoint of the Finnish 400 kV power system, and the resulting geomagnetically-induced currents (GICs) in the system are computed. In the north, i.e. near the electrojet, GICs may have values even in the order of hundreds of amperes. A comparison to GICs produced by an equivalent spatially-constant external electric field is demonstrated. Sometimes the location of the electrojet is further south. This possibility is studied by letting the line current have several different locations above the Finnish power grid

  14. Alien species in the Finnish weed flora

    Directory of Open Access Journals (Sweden)

    T. HYVÖNEN

    2008-12-01

    Full Text Available The present study aimed at assessing the invasion of alien weed species in Finland based on a review of their occurrence in the Finnish weed flora. The evaluation was conducted for the three phases of the invasion process, i.e. introduction, naturalization and invasion. The literature review revealed that 815 alien weed species occur in Finland of which 314 are regarded as naturalized. Based on their occurrence in different climate zones, the risk of naturalization of new harmful alien weed species was deemed low for those species not currently found in Finland, but higher for species occurring as casual aliens in Finland. In the latter group, 10 species of concern were detected. Exploration of the distribution patterns of naturalized species within Finland revealed species occupancy to be dependent on the residence time of the species. Established neophytes can be expected to extend their ranges and to increase occupation of agricultural habitats in the future.;

  15. How Finnish and Swedish Learners’ Academic Self-Control Relates to Time Spent Online in Class, Perceptions of Educator Qualities, and School Appreciation: A Cross-Sectional Comparison

    Directory of Open Access Journals (Sweden)

    Thomas Arnesen

    2017-08-01

    Full Text Available In school settings, self-control is central to the ability of learners to complete their academic work successfully. Learners’ self-control is directly influenced by the ways in which educators execute their work, including their instructional explanations, their classroom management, and the expectations that they express to their learners. Our research on this phenomenon investigated Finnish and Swedish learners in upper secondary schools. Not only is the use of digital technology very different in these two countries; the autonomy and status of educators are as well. This article compares the empirical significance of antecedents of learners’ academic self-control in the two national settings by surveying 2191 learners in Swedish and Finnish schools. Our analysis applies structural equation modeling to two cross-sectional datasets, and the results reveal that the associations between educators’ instructional explanations, classroom management, and their high expectations on the one hand and learners’ academic self-control on the other are stronger overall among Finnish students than among Swedish students. Furthermore, the association between digital technology use and learners’ perceptions of conflict between school norms and Internet opportunities are much stronger in the Swedish sample than the Finnish sample. Lastly, we discuss the meaning of these results and their possible implications for research and practice.

  16. Regulated and Liberated Bodies of Schoolgirls in a Finnish Short Film from the 1950s

    Science.gov (United States)

    Nieminen, Marjo

    2018-01-01

    This article focuses on the bodies of schoolgirls as visualised and represented in a short film of Finnish secondary schools for girls in the 1950s. The film, "Oma tyttökouluni" ("My Own Girls' School") was released in 1957 and was screened in cinemas in advance of feature films. Although the short film was made in a…

  17. Analysis of the Development of Academic Writing in the "FJNSc" ("Finnish Journal of Nursing Science")

    Science.gov (United States)

    Vanhanen-Nuutinen, Liisa; Janhonen, Sirpa; Tuomi, Jouni

    2012-01-01

    The purpose of this paper is to analyze the genre of the reviewed scientific articles published in the "FJNSc" ("Finnish Journal of Nursing Science") during its history. The aim was to bring a critical approach to writing in nursing science and to discuss the dominant conventions of scientific writing in nursing. A total of 27…

  18. A role for MLH3 in hereditary nonpolyposis colorectal cancer

    NARCIS (Netherlands)

    Wu, Y; Berends, MJW; Sijmons, RH; Mensink, RGJ; Verlind, E; Kooi, KA; van der Sluis, T; Kempinga, C; van der Zee, AGJ; Hollema, H; Buys, CHCM; Kleibeuker, JH; Hofstra, RMW

    2001-01-01

    We investigated a possible role of the mismatch-repair gene MLH3 in hereditary nonpolyposis colorectal cancer by scanning for mutations in 39 HNPCC families and in 288 patients suspected of having HNPCC. We identified ten different germline MLH3 variants, one frameshift and nine missense mutations,

  19. Locating a Prostate Cancer Susceptibility Gene on the X Chromosome by Linkage Disequilibrium Mapping Using Three Founder Populations in Quebec and Switzerland

    Science.gov (United States)

    2006-09-01

    Gordon PH, Wang Q, Puisieux, A, Foulkes WD and Trifiro M. Polymorphisms and HNPCC: PMS2 -MLH1 protein interactions diminished by ‘single nucleotide...and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC). Genes Chromosomes Cancer, 44 (2): 123-38, 2005. 120. Soravia C

  20. Approaches to diagnose DNA mismatch repair gene defects in cancer

    DEFF Research Database (Denmark)

    Peña-Diaz, Javier; Rasmussen, Lene Juel

    2016-01-01

    development was first observed in colorectal cancer patients that carried inactivating germline mutations in MMR genes and the disease was named as hereditary non-polyposis colorectal cancer (HNPCC). Currently, a growing list of cancers is found to be MMR defective and HNPCC has been renamed Lynch syndrome...

  1. Emergence and translations of management interests in corporate branding in the Finnish pulp and paper corporations : a study with an actor-network theory approach

    OpenAIRE

    Aspara, Jaakko

    2007-01-01

    The riddle of this Thesis is: How come the management of the Finnish pulp and paper (P&P) corporations became interested in corporate branding around the year 2000? By the Finnish P&P corporations, I refer particularly to the three large P&P corporations based in Finland in 2005: UPM-Kymmene, Stora Enso, and M-Real. By the management, I refer to managers of these corporations including the top managers, i.e. CEOs and executive board members, and even the members of the Boards of Directors. ...

  2. Distribution and medical impact of loss-of-function variants in the Finnish founder population.

    Directory of Open Access Journals (Sweden)

    Elaine T Lim

    2014-07-01

    Full Text Available Exome sequencing studies in complex diseases are challenged by the allelic heterogeneity, large number and modest effect sizes of associated variants on disease risk and the presence of large numbers of neutral variants, even in phenotypically relevant genes. Isolated populations with recent bottlenecks offer advantages for studying rare variants in complex diseases as they have deleterious variants that are present at higher frequencies as well as a substantial reduction in rare neutral variation. To explore the potential of the Finnish founder population for studying low-frequency (0.5-5% variants in complex diseases, we compared exome sequence data on 3,000 Finns to the same number of non-Finnish Europeans and discovered that, despite having fewer variable sites overall, the average Finn has more low-frequency loss-of-function variants and complete gene knockouts. We then used several well-characterized Finnish population cohorts to study the phenotypic effects of 83 enriched loss-of-function variants across 60 phenotypes in 36,262 Finns. Using a deep set of quantitative traits collected on these cohorts, we show 5 associations (p<5×10⁻⁸ including splice variants in LPA that lowered plasma lipoprotein(a levels (P = 1.5×10⁻¹¹⁷. Through accessing the national medical records of these participants, we evaluate the LPA finding via Mendelian randomization and confirm that these splice variants confer protection from cardiovascular disease (OR = 0.84, P = 3×10⁻⁴, demonstrating for the first time the correlation between very low levels of LPA in humans with potential therapeutic implications for cardiovascular diseases. More generally, this study articulates substantial advantages for studying the role of rare variation in complex phenotypes in founder populations like the Finns and by combining a unique population genetic history with data from large population cohorts and centralized research access to National Health

  3. Relationships of body weight and carcass quality traits with first lactation milk production in Finnish Ayrshire cows

    NARCIS (Netherlands)

    Liinamo, A.E.; Ojala, M.; Arendonk, van J.A.M.

    1999-01-01

    Relationships of body weight and carcass quality traits with first lactation milk production traits were estimated from a field data set of 28362 Finnish Ayrshire cows, using REML methodology and animal model. Studied body weight traits included heifer and mature live weight, estimated based on

  4. Screening for susceptibility genes in hereditary non-polyposis colorectal cancer.

    Science.gov (United States)

    Yu, Li; Yin, Bo; Qu, Kaiying; Li, Jingjing; Jin, Qiao; Liu, Ling; Liu, Chunlan; Zhu, Yuxing; Wang, Qi; Peng, Xiaowei; Zhou, Jianda; Cao, Peiguo; Cao, Ke

    2018-06-01

    In the present study, hereditary non-polyposis colorectal cancer (HNPCC) susceptibility genes were screened for using whole exome sequencing in 3 HNPCC patients from 1 family and using single nucleotide polymorphism (SNP) genotyping assays in 96 other colorectal cancer and control samples. Peripheral blood was obtained from 3 HNPCC patients from 1 family; the proband and the proband's brother and cousin. High-throughput sequencing was performed using whole exome capture technology. Sequences were aligned against the HAPMAP, dbSNP130 and 1,000 Genome Project databases. Reported common variations and synonymous mutations were filtered out. Non-synonymous single nucleotide variants in the 3 HNPCC patients were integrated and the candidate genes were identified. Finally, SNP genotyping was performed for the genes in 96 peripheral blood samples. In total, 60.4 Gb of data was retrieved from the 3 HNPCC patients using whole exome capture technology. Subsequently, according to certain screening criteria, 15 candidate genes were identified. Among the 96 samples that had been SNP genotyped, 92 were successfully genotyped for 15 gene loci, while genotyping for HTRA1 failed in 4 sporadic colorectal cancer patient samples. In 12 control subjects and 81 sporadic colorectal cancer patients, genotypes at 13 loci were wild-type, namely DDX20, ZFYVE26, PIK3R3, SLC26A8, ZEB2, TP53INP1, SLC11A1, LRBA, CEBPZ, ETAA1, SEMA3G, IFRD2 and FAT1 . The CEP290 genotype was mutant in 1 sporadic colorectal cancer patient and was wild-type in all other subjects. A total of 5 of the 12 control subjects and 30 of the 81 sporadic colorectal cancer patients had a mutant HTRA1 genotype. In all 3 HNPCC patients, the same mutant genotypes were identified at all 15 gene loci. Overall, 13 potential susceptibility genes for HNPCC were identified, namely DDX20, ZFYVE26, PIK3R3, SLC26A8, ZEB2, TP53INP1, SLC11A1, LRBA, CEBPZ, ETAA1, SEMA3G, IFRD2 and FAT1 .

  5. Divorce Risk Factors Across Finnish Marriage cohorts, 1954-1989

    Directory of Open Access Journals (Sweden)

    Juho Härkönen

    2005-01-01

    Full Text Available This paper examines whether there has been a change in the effects of three divorce risk factors, female educational attainment, cohabitation, and parity. Several theoretical reasons suggest such a change, but the existing evidence gives mixed results. First marriages of Finnish women married between 1954 and 1989 are analysed using data from the Fertility and Family Surveys (FFS, collected in 1989 and 1990. The results from the discrete-time event history models show that the effect of having children on marital stability has changed: the impact of having two children has become less evident, while the effect of having three children or more has increased. These trends hold after controlling for young children and premarital children. Some explanations for this shift are discussed.

  6. Young People’s Attitudes towards Entrepreneurship in Finnish Society

    Directory of Open Access Journals (Sweden)

    Teemu Rantanen

    2012-01-01

    Full Text Available In this study, we analyze youngpeople’sattitudes towards entrepreneurship in theHelsinki-Uusimaa region of Finland.First, ourtheoretical framework links withattitude research, in particular, Ajzen’s theory of planned behavior. Our secondperspective derives from the theory of representations. Third, our analysis is basedon discussionsofthe welfare state and democratic values. We ask what socialpsychological factors explain young people’s entrepreneurial intentions. Surveydata (N=873was collected in electronic formatfromsecondary and vocationalschools. The questions were mainly multiple choiceLikert-scalequestions. Theanalysis was undertaken using simple statistical methods. Our results demonstratethat the relationship betweensocial values, representations concerningentrepreneurship,and entrepreneurial intention is complex in the Finnish context.Whilewe further argue thatthetheory of planned behavior is valid in thisinstance, the representations and social values serve to explain entrepreneurialintentiononly weakly.

  7. The stubborn peasant and the Frenchmen of the North : Swedish and Finnish ethnicity and national historical writing in Swedish and Finland-Swedish textbooks 1866-1939

    OpenAIRE

    Spjut, Lina

    2014-01-01

    Sweden and Finland were one country for more than 600 years and there are many remaining links between the two countries. Throughout the period, but even today there are Swedish and Finnish populations on both sides of the Gulf of Bothnia. When Russia conquered the Finnish part of the country in 1809, the state and its population were separated and the situations for the language groups changed and developed differently in Sweden and Finland. During the period studied in this thesis, 1866-193...

  8. Molecular and clinical characteristics of MSH6 variants : An analysis of 25 index carriers of a germline variant

    NARCIS (Netherlands)

    Olderode - Berends, Maria; Wu, Ying; Sijmons, RH; Mensink, RGJ; van der Sluis, T; Hordijk-Hos, JM; de Vries, EGE; Hollema, H; Karrenbeld, Arend; Buys, CHCM; van der Zee, AGJ; Hofstra, RMW; Kleibeuker, JH

    The MSH6 gene is one of the mismatch-repair genes involved in hereditary nonpolyposis colorectal cancer (HNPCC). Three hundred sixteen individuals who were known or suspected to have HNPCC were analyzed for MSH6 germline mutations. For 25 index patients and 8 relatives with MSH6 variants, molecular

  9. National Assessment Meets Teacher Autonomy: National Assessment of Learning Outcomes in Music in Finnish Basic Education

    Science.gov (United States)

    Juntunen, Marja-Leena

    2017-01-01

    In Finland, teachers' have extensive autonomy, that is freedom from control by others over their professional actions in the classroom, and it is considered a strength of Finnish education. At the same time, national assessment of learning outcomes has been constructed to examine the learner's progress and achievements in relation to the criteria…

  10. A Postcolonial Discourse Analysis of Finnish School Textbooks: Learning about the World from a Tourist Perspective

    Science.gov (United States)

    Mikander, Pia; Zilliacus, Harriet

    2016-01-01

    In this article, we ask how Finnish basic education school textbooks in social science portray tourism and countries with a big tourism sector. We have analyzed the textbook quotes from a postcolonial perspective, using discourse theory analysis. The idea is to challenge what is considered objective information about tourist locations in school…

  11. [Terhi Kiiskinen. Library of the Finnish nobleman, royal secretary and trustee Henrik Matsson (ca 1540-1617)] / Liivi Aarma

    Index Scriptorium Estoniae

    Aarma, Liivi, 1948-

    2009-01-01

    Arvustus: Kiiskinen, Terhi. Library of the Finnish nobleman, royal secretary and trustee Henrik Matsson (ca 1540-1617). Helsinki, 2004. Terhi Kiiskinen valgustab Forsiuse lugemust temaga seotud ajaloolise isiku Henrik Matsson Hugguti raamatukogu kataloogi abil, mis on säilinud Tallinna Linnaarhiivis

  12. Finland Has it All? Examining the Media Accentuation of "Finnish Education" in Australia, Germany and South Korea

    Science.gov (United States)

    Takayama, Keita; Waldow, Florian; Sung, Youl-Kwan

    2013-01-01

    Drawing on the conceptual work of externalisation in comparative education and multi-accentual signs in cultural studies, this article examines how the print news media accentuate "Finnish education" in the process of inserting this external reference into the domestic political discourses around education reform in Australia, Germany…

  13. The classification of knowledge and expertise in Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Kuronen, T.; Rintala, N.

    2006-01-01

    The difficulties in sharing tacit knowledge may compromise the safe performance of high-reliability organisations. This threat has been recognised in nuclear power plants worldwide, owing to the risk of simultaneous retirements. In this study, the nature of tacit knowledge in Finnish nuclear power plants was examined and the expertise of nuclear workers modelled. The results of this interview study showed that the tacit nuclear knowledge can be classified in two dimensions: technical and contextual. According to this classification, the employees in plants can be categorised in four categories: the experts; the novices; the technical specialists; the context sensitives. (author)

  14. The Journalists as a Brand: a comparative study between Finnish and Portuguese journalists

    OpenAIRE

    Heidi Maarit Anneli Rasi

    2015-01-01

    This work explores has personal branding started to be part of journalists profession. In a time when journalism is said to be in crises because of globalization, reductions in media houses and European economic crisis the topic of this survey is important."The Journalist as a Brand" inquiry was sent to 60 journalists from Finland and Portugal in spring 2015. The comparative inquiry explored the differences in journalists attitudes toward personal branding among Finnish and Portuguese journal...

  15. Trust in Management under Post-bureaucratic Conditions: The Case of Finnish Civil Servants

    Directory of Open Access Journals (Sweden)

    Jaakko Koivumäki

    2013-12-01

    Full Text Available The Finnish state administration has recently undergone a wave of reforms towards decentralized decision-making and increased flexibility in organizing work. Traditional bureaucracy, however, has its virtues. Based on a survey and qualitative interview material, the results presented in this paper indicate that many characteristics of bureaucracy, such as well-defined work roles and hierarchical control, facilitate trust among employees. In contrast, the current post-bureaucratic model of organizing work may increase insecurity and decrease trust.

  16. GPS positioning and desktop mapping. Applications to environmental monitoring. Report on task JNT B898 on the Finnish support programme to IAEA safeguards

    International Nuclear Information System (INIS)

    Kansanaho, A.; Ilander, T.; Toivonen, H.

    1995-10-01

    Satellite navigation has been used for in-field applications by the Finnish Centre for Radiation and Nuclear Safety since 1993. Because of this experience, training in the use of GPS positioning and desktop mapping was chosen as a task under the Finnish Support programme to IAEA safeguards. A lecture and a field experiment was held in the training course on environmental monitoring at the IAEA headquarters in June 1995. Real-time mapping of the co-ordinates and storing information on sampling sites and procedures can make safeguards implementation more efficient and effective. Further software development are needed for these purposes. (author) (6 figs.)

  17. Operation of Finnish nuclear power plants. Quarterly report, 3rd quarter 1997

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1998-04-01

    Quarterly reports on the operation of Finnish nuclear power plants describe events and observations relating to nuclear and radiation safety that the Radiation and Nuclear Safety Authority of Finland (STUK) considers safety significant. Safety improvements at the plants are also described. The Report also includes a summary of the radiation safety of plant personnel and of the environment and tabulated data on the plants' production and load factors. The Finnish nuclear power plant units were in power operation in the third quarter of 1997, except for the annual maintenance outages of Loviisa plant units which lasted well over a month in all. There was also a brief interruption in electricity generation at Olkiluoto 1 for repairs and at Olkiluoto 2 due to a disturbance at the turbine plant. All plant units were in long-term test operation at upgraded reactor power level approved by STUK. The load factor average of all plant units was 87.6 %. One event in the third quarter was classified level 1 on the International Nuclear Event Scale (INES). It was noted at Loviisa 2 that one of four pressurized water tanks in the plant unit's emergency cooling system had been inoperable for a year. Other events in this quarter were INES level 0. Occupational doses and radioactive releases off-site were below authorized limits. Radioactive substances were measurable in samples collected around the plants in such quantities only as have no bearing on the radiation exposure of the population. (orig.)

  18. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1992-12-01

    The Finnish nuclear power plant units Loviisa 1 and 2 as well TVO I and II were in operation for almost the whole second quarter of 1992. Longer breaks in production were caused by the annual maintenance of the TVO plant units. The load factor was 87.4 %. At TVO I it was detected during the annual maintenance outage when removing nuclear fuel assemblies from the reactor that one assembly had been loaded into the reactor in an incorrect manner during the previous year's annual maintenance: the assembly was slightly higher than the other assemblies. The water cooling the nuclear fuel partly by-passed the fuel assembly and the coolant flow proper passing through the assembly was below design. The fuel assembly's cooling had been sufficient during the whole operating cycle but could have essentially deteriorated during certain transients with the danger of consequent damage to some fuel rods. On the International Nuclear Event Scale the event is classified as level 1. Other events in this quarter which are classified on the International Nuclear Event Scale were level 0/below scale on the scale

  19. Operation of Finnish nuclear power plants

    International Nuclear Information System (INIS)

    Tossavainen, K.

    1992-03-01

    The Finnish nuclear power plant units Loviisa 1 and 2 as well as TVO I and II were in operation for almost the whole third quarter of 1991. Longer interruptions in electricity generation were caused by the annual maintenances of the Loviisa plant units. The load factor average was 81.7 %. In a test conducted during the annual maintenance outage of Loviisa 1 it was detected that the check valve of the discharge line of one pressurized emergency make-up tank did not open sufficiently at the tank's hydrostatic pressure. In connection with a 1988 modification, a too tightly dimensioned bearing had been mounted on the valve's axle rod and the valve had not been duly tested after the operation. The event is classified as Level 1 on the International Nuclear Event Scale. Other events in this quarter which are classified according to the International Nuclear Event Scale are Level Zero (Below Scale). Occupational radiation doses and releases of radioactive material off-site were below authorised limits in this quarter. Only small amounts of radioactive materials originating in nuclear power plants were detected in samples taken in the vicinity of nuclear power plants

  20. Control of radon in Finnish workplaces

    International Nuclear Information System (INIS)

    Markkanen, M.

    2002-01-01

    Natural radiation in Finland is regulated in the Finnish Radiation Act from 1992. Occupational exposure to natural radiation is regulated by an amendment of the Radiation Decree in 1998. The most important issues in Finland are radon in workplaces, radioactivity in drinking water and in building materials, and mining and industrial processes. Radon levels in mines have been measured regularly since 1972. Finland has an action level for radon in workplaces of 400 Bq/m 3 . Radon prone areas have been identified primarily from measurements of radon in dwellings. Radon measurements are compulsory in workplaces in radon prone areas unless it can be shown by other means that radon levels are low. A programme focusing on radon in workplaces was initiated in 1992. To date, radon measurements have been carried out in 10,000 workplaces and remedial actions have been taken in 200 of these. The average reduction in radon concentration in remediated buildings is about 1,500 Bq/m 3 . Identification of NORM industries is based on the radionuclide content of the materials used (>1.4 Bq/g U and >0.4 Bq/g Th). The occupational exposure should not exceed 1 mSv/y (excluding radon)