WorldWideScience

Sample records for final irreversible counting

  1. Examination of various postulates of irreversibility

    Energy Technology Data Exchange (ETDEWEB)

    Salmon, J [Conservatoire National des Arts et Metiers (CNAM), 75 - Paris (France)

    1977-01-01

    Firstly, it is shown that it is necessary to break the reversible character of the B.B.G.K.Y. system of equations by means of a postulate of irreversibility to obtain a kinetic equation compatible with the second principle of thermodynamics. Next, three postulates of irreversibility are examined: that of molecular chaos, that of linear relaxation and, finally, that of superposition. Then the corresponding kinetic equations and the expressions for the viscosity coefficient to which they lead are determined. Comparison with experiment is made each time. Lastly, an attempt to obtain an irreversible kinetic equation without introducing a postulate of irreversibility in the B.B.G.K.Y. system is realized. This consists in adding a complementary irreversible term to the fundamental equation of the dynamics of a particle. The suggested term is of quantum origin and leads to a kinetic equation of the Fokker-Planck type.

  2. Irreversible thermodynamic analysis and application for molecular heat engines

    Science.gov (United States)

    Lucia, Umberto; Açıkkalp, Emin

    2017-09-01

    Is there a link between the macroscopic approach to irreversibility and microscopic behaviour of the systems? Consumption of free energy keeps the system away from a stable equilibrium. Entropy generation results from the redistribution of energy, momentum, mass and charge. This concept represents the essence of the thermodynamic approach to irreversibility. Irreversibility is the result of the interaction between systems and their environment. The aim of this paper is to determine lost works in a molecular engine and compare results with macro (classical) heat engines. Firstly, irreversible thermodynamics are reviewed for macro and molecular cycles. Secondly, irreversible thermodynamics approaches are applied for a quantum heat engine with -1/2 spin system. Finally, lost works are determined for considered system and results show that macro and molecular heat engines obey same limitations. Moreover, a quantum thermodynamic approach is suggested in order to explain the results previously obtained from an atomic viewpoint.

  3. Irreversible social change

    NARCIS (Netherlands)

    Pols, A.J.K.; Romijn, H.A.; Collste, G.; Reuter, L.

    2014-01-01

    In this paper we evaluate how irreversible social change should be evaluated from an ethical perspective. First; we analyse the notion of irreversibility in general terms. We define a general notion of what makes a change irreversible; drawing on discussions in ecology and economics. This notion is

  4. Attribution of irreversible loss to anthropogenic climate change

    Science.gov (United States)

    Huggel, Christian; Bresch, David; Hansen, Gerrit; James, Rachel; Mechler, Reinhard; Stone, Dáithí; Wallimann-Helmer, Ivo

    2016-04-01

    The Paris Agreement (2015) under the UNFCCC has anchored loss and damage in a separate article which specifies that understanding and support should be enhanced in areas addressing loss and damage such as early warning, preparedness, insurance and resilience. Irreversible loss is a special category under loss and damage but there is still missing clarity over what irreversible loss actually includes. Many negative impacts of climate change may be handled or mitigated by existing risk management, reduction and absorption approaches. Irreversible loss, however, is thought to be insufficiently addressed by risk management. Therefore, countries potentially or actually affected by irreversible loss are calling for other measures such as compensation, which however is highly contested in international climate policy. In Paris (2015) a decision was adopted that loss and damage as defined in the respective article of the agreement does not involve compensation and liability. Nevertheless, it is likely that some sort of mechanism will eventually need to come into play for irreversible loss due to anthropogenic climate change, which might involve compensation, other forms of non-monetary reparation, or transformation. Furthermore, climate litigation has increasingly been attempted to address negative effects of climate change. In this context, attribution is important to understand the drivers of change, what counts as irreversible loss due to climate change, and, possibly, who or what is responsible. Here we approach this issue by applying a detection and attribution perspective on irreversible loss. We first analyze detected climate change impacts as assessed in the IPCC Fifth Assessment Report. We distinguish between irreversible loss in physical, biological and human systems, and accordingly identify the following candidates of irreversible loss in these systems: loss of glaciers and ice sheets, loss of subsurface ice (permafrost) and related loss of lake systems; loss

  5. Irreversible stochastic processes on lattices

    International Nuclear Information System (INIS)

    Nord, R.S.

    1986-01-01

    Models for irreversible random or cooperative filling of lattices are required to describe many processes in chemistry and physics. Since the filling is assumed to be irreversible, even the stationary, saturation state is not in equilibrium. The kinetics and statistics of these processes are described by recasting the master equations in infinite hierarchical form. Solutions can be obtained by implementing various techniques: refinements in these solution techniques are presented. Programs considered include random dimer, trimer, and tetramer filling of 2D lattices, random dimer filling of a cubic lattice, competitive filling of two or more species, and the effect of a random distribution of inactive sites on the filling. Also considered is monomer filling of a linear lattice with nearest neighbor cooperative effects and solve for the exact cluster-size distribution for cluster sizes up to the asymptotic regime. Additionally, a technique is developed to directly determine the asymptotic properties of the cluster size distribution. Finally cluster growth is considered via irreversible aggregation involving random walkers. In particular, explicit results are provided for the large-lattice-size asymptotic behavior of trapping probabilities and average walk lengths for a single walker on a lattice with multiple traps. Procedures for exact calculation of these quantities on finite lattices are also developed

  6. Time in Science: Reversibility vs. Irreversibility

    Science.gov (United States)

    Pomeau, Yves

    To discuss properly the question of irreversibility one needs to make a careful distinction between reversibility of the equations of motion and the choice of the initial conditions. This is also relevant for the rather confuse philosophy of the wave packet reduction in quantum mechanics. The explanation of this reduction requires also to make precise assumptions on what initial data are accessible in our world. Finally I discuss how a given (and long) time record can be shown in an objective way to record an irreversible or reversible process. Or: can a direction of time be derived from its analysis? This leads quite naturally to examine if there is a possible spontaneous breaking of the time reversal symmetry in many body systems, a symmetry breaking that would be put in evidence objectively by looking at certain specific time correlations.

  7. Irreversibility analysis in the process of solar distillation

    International Nuclear Information System (INIS)

    Chávez, S; Terres, H; Lizardi, A; López, R; Lara, A

    2017-01-01

    In this work an irreversibility analysis for the thermal process of solar distillation of three different substances is presented, for which it employs a solar still of a slope where three experimental tests with 5.5 L of brine, river water and MgCl 2 were performed. Temperature data principally in the glass cover, absorber plate, fluid, environment and the incident solar radiation on the device were obtained. With measurements of temperature, solar radiation and exergetic balance, irreversibilities are found on the device. The results show that the highest values of irreversibilities are concentrated in the absorber plate with an average of 321 W, 342 W and 276 W, followed by the cover glass with an average of 75.8 W, 80.4 W and 86.7 W and finally the fluid with 15.3 W, 15.9 W and 16 W, for 5.5 L of brine, river water and MgCl 2 . (paper)

  8. Optima and bounds for irreversible thermodynamic processes

    International Nuclear Information System (INIS)

    Hoffmann, K.H.

    1990-01-01

    In this paper bounds and optima for irreversible thermodynamic processes and their application in different fields are discussed. The tools of finite time thermodynamics are presented and especially optimal control theory is introduced. These methods are applied to heat engines, including models of the Diesel engine and a light-driven engine. Further bounds for irreversible processes are introduced, discussing work deficiency and its relation to thermodynamic length. Moreover the problem of dissipation in systems composed of several subsystems is studied. Finally, the methods of finite time thermodynamics are applied to thermodynamic processes described on a more microscopic level. The process used as an example is simulated annealing. It is shown how optimal control theory is applied to find the optimal cooling schedule for this important stochastic optimization method

  9. Multiscale Analysis of Time Irreversibility Based on Phase-Space Reconstruction and Horizontal Visibility Graph Approach

    Science.gov (United States)

    Zhang, Yongping; Shang, Pengjian; Xiong, Hui; Xia, Jianan

    Time irreversibility is an important property of nonequilibrium dynamic systems. A visibility graph approach was recently proposed, and this approach is generally effective to measure time irreversibility of time series. However, its result may be unreliable when dealing with high-dimensional systems. In this work, we consider the joint concept of time irreversibility and adopt the phase-space reconstruction technique to improve this visibility graph approach. Compared with the previous approach, the improved approach gives a more accurate estimate for the irreversibility of time series, and is more effective to distinguish irreversible and reversible stochastic processes. We also use this approach to extract the multiscale irreversibility to account for the multiple inherent dynamics of time series. Finally, we apply the approach to detect the multiscale irreversibility of financial time series, and succeed to distinguish the time of financial crisis and the plateau. In addition, Asian stock indexes away from other indexes are clearly visible in higher time scales. Simulations and real data support the effectiveness of the improved approach when detecting time irreversibility.

  10. Summative Self-Assessment in Higher Education: Implications of Its Counting towards the Final Mark

    Science.gov (United States)

    Tejeiro, Ricardo A.; Gomez-Vallecillo, Jorge L.; Romero, Antonio F.; Pelegrina, Manuel; Wallace, Agustin; Emberley, Enrique

    2012-01-01

    Introduction: Our study aims at assessing the validity of summative criteria-referenced self-assessment in higher education, and in particular, if that validity varies when the professor counts self-assessment toward the final mark. Method: One hundred and twenty-two first year students from two groups in Teacher Education at the Universidad de…

  11. Irreversible processes kinetic theory

    CERN Document Server

    Brush, Stephen G

    2013-01-01

    Kinetic Theory, Volume 2: Irreversible Processes deals with the kinetic theory of gases and the irreversible processes they undergo. It includes the two papers by James Clerk Maxwell and Ludwig Boltzmann in which the basic equations for transport processes in gases are formulated, together with the first derivation of Boltzmann's ""H-theorem"" and a discussion of this theorem, along with the problem of irreversibility.Comprised of 10 chapters, this volume begins with an introduction to the fundamental nature of heat and of gases, along with Boltzmann's work on the kinetic theory of gases and s

  12. Irreversibility and self-organization in spin glasses. 1. Origin of irreversibility in spin glasses

    International Nuclear Information System (INIS)

    Kovrov, V.P.; Kurbatov, A.M.

    1989-05-01

    The origin of irreversibility in spin glasses is found out on the basis of the analytical study of the well-known TAP equations. Connection between irreversible jumpwise transitions and a positive feedback in spin glasses is discussed. (author). 7 refs, 4 figs

  13. How to account for irreversibility in integrated assessment of climate change?

    International Nuclear Information System (INIS)

    Ha Duong, M.

    1998-04-01

    How to account for irreversibility in integrated assessment of climate change? This Ph. D. thesis in Economics balances discounting, technical progress and the inertia of existing capital stock against uncertainty and the inertia of socio-economic systems to examine the issue of near term limitations of greenhouse gases emissions. After a general overview in chapter 2, and a more historical presentation of the debates in chapter 3, chapter 4 proceeds to review a large number of integrated assessment models. Chapter 5 introduces a Model on the Dynamics of Inertia and Adaptability of energy systems: DIAM, used to discuss how much previous studies might have overestimated the long term costs of CO 2 limitations and underestimated adjustment costs. It shows that, given a target date for atmospheric CO 2 concentration stabilisation, a higher inertia implies a lower optimal concentration trajectory. In a sequential decision framework, chapter 6 shows that current uncertainties about which CO 2 concentration ceiling would not present dangerous interference with the climate system justifies precautionary action. Finally, chapter 7 uses the irreversibility effect theory to define formally situations of decision under controversy and compare the irreversibility of CO 2 accumulation with the irreversibility of investments needed to moderate it. An option value for greenhouse gases emissions limitations is computed. (author)

  14. Variability of Irreversible Poleward Transport in the Lower Stratosphere

    Science.gov (United States)

    Olsen, Mark; Douglass, Anne; Newman, Paul; Nash, Eric; Witte, Jacquelyn; Ziemke, Jerry

    2011-01-01

    The ascent and descent of the Brewer-Dobson circulation plays a large role in determining the distributions of many constituents in the extratropical lower stratosphere. However, relatively fast, quasi-horizontal transport out of the tropics and polar regions also significantly contribute to determining these distributions. The tropical tape recorder signal assures that there must be outflow from the tropics into the extratropical lower stratosphere. The phase of the quasi-biennial oscillation (QBO) and state of the polar vortex are known to modulate the transport from the tropical and polar regions, respectively. In this study we examine multiple years of ozone distributions in the extratropical lower stratosphere observed by the Aura Microwave Limb Sounder (MLS) and the Aura High Resolution Dynamic Limb Sounder (HIRDLS). The distributions are compared with analyses of irreversible, meridional isentropic transport. We show that there is considerable year-to-year seasonal variability in the amount of irreversible transport from the tropics, which is related to both the phase of the QBO and the state of the polar vortex. The reversibility of the transport is consistent with the number of observed breaking waves. The variability of the atmospheric index of refraction in the lower stratosphere is shown to be significantly correlated with the wave breaking and amount of irreversible transport. Finally, we will show that the seasonal extratropical stratosphere to troposphere transport of ozone can be substantially modulated by the amount of irreversible meridional transport in the lower stratosphere and we investigate how observable these differences are in data of tropospheric ozone.

  15. Ecological optimization for generalized irreversible Carnot refrigerators

    International Nuclear Information System (INIS)

    Chen Lingen; Zhu Xiaoqin; Sun Fengrui; Wu Chih

    2005-01-01

    The optimal ecological performance of a Newton's law generalized irreversible Carnot refrigerator with the losses of heat resistance, heat leakage and internal irreversibility is derived by taking an ecological optimization criterion as the objective, which consists of maximizing a function representing the best compromise between the exergy output rate and exergy loss rate (entropy production rate) of the refrigerator. Numerical examples are given to show the effects of heat leakage and internal irreversibility on the optimal performance of generalized irreversible refrigerators

  16. Entropy, Extropy and the Physical Driver of Irreversibility

    Directory of Open Access Journals (Sweden)

    Attila Grandpierre

    2012-06-01

    Full Text Available We point out that the fundamental irreversibility of Nature requires the introduction of a suitable measure for the distance from equilibrium. We show that entropy, which is widely held to be such a measure, suffers from the problem that it does not have a physical meaning, since it is introduced on the basis of mathematical arguments. As a consequence, the basic physics beyond irreversibility has remained obscure. We present here a simple but transparent physical approach for solving the problem of irreversibility. This approach shows that extropy, the fundamental thermodynamic variable introduced by Katalin Martinás, is the suitable measure for the distance from equilibrium, since it corresponds to the actual driver of irreversible processes. Since extropy explicitly contains in its definition all the general thermodynamic forces that drive irreversible processes, extropy is the suitable physical measure of irreversibility.

  17. Irreversible dynamics, Onsager-Casimir symmetry, and an application to turbulence.

    Science.gov (United States)

    Ottinger, Hans Christian

    2014-10-01

    Irreversible contributions to the dynamics of nonequilibrium systems can be formulated in terms of dissipative, or irreversible, brackets. We discuss the structure of such irreversible brackets in view of a degeneracy implied by energy conservation, where we consider different types of symmetries of the bracket corresponding to the Onsager and Casimir symmetries of linear irreversible thermodynamics. Slip and turbulence provide important examples of antisymmetric irreversible brackets and offer guidance for the more general modeling of irreversible dynamics without entropy production. Conversely, turbulence modeling could benefit from elucidating thermodynamic structure. The examples suggest constructing antisymmetric irreversible brackets in terms of completely antisymmetric functions of three indices. Irreversible brackets without well-defined symmetry properties can arise for rare events, causing big configurational changes.

  18. Logic reversibility and thermodynamic irreversibility demonstrated by DNAzyme-based Toffoli and Fredkin logic gates.

    Science.gov (United States)

    Orbach, Ron; Remacle, Françoise; Levine, R D; Willner, Itamar

    2012-12-26

    The Toffoli and Fredkin gates were suggested as a means to exhibit logic reversibility and thereby reduce energy dissipation associated with logic operations in dense computing circuits. We present a construction of the logically reversible Toffoli and Fredkin gates by implementing a library of predesigned Mg(2+)-dependent DNAzymes and their respective substrates. Although the logical reversibility, for which each set of inputs uniquely correlates to a set of outputs, is demonstrated, the systems manifest thermodynamic irreversibility originating from two quite distinct and nonrelated phenomena. (i) The physical readout of the gates is by fluorescence that depletes the population of the final state of the machine. This irreversible, heat-releasing process is needed for the generation of the output. (ii) The DNAzyme-powered logic gates are made to operate at a finite rate by invoking downhill energy-releasing processes. Even though the three bits of Toffoli's and Fredkin's logically reversible gates manifest thermodynamic irreversibility, we suggest that these gates could have important practical implication in future nanomedicine.

  19. Hydraulically irreversible fouling on ceramic MF/UF membranes: comparison of fouling indices, foulant composition and irreversible pore narrowing

    KAUST Repository

    Shang, Ran; Vuong, Francois; Hu, Jingyi; Li, Sheng; Kemperman, Antoine J.B.; Nijmeijer, Kitty; Cornelissen, Emile R.; Heijman, Sebastiaan G.J.; Rietveld, Luuk C.

    2015-01-01

    The application of ceramic membranes in water treatment is becoming increasing attractive because of their long life time and excellent chemical, mechanical and thermal stability. However, fouling of ceramic membranes, especially hydraulically irreversible fouling, is still a critical aspect affecting the operational cost and energy consumption in water treatment plants. In this study, four ceramic membranes with pore sizes or molecular weight cut-off (MWCO) of 0.20 μm, 0.14 μm, 300 kDa and 50 kDa were compared during natural surface water filtration with respect to hydraulically irreversible fouling index (HIFI), foulant composition and narrowing of pore size due to the irreversible fouling. Our results showed that the hydraulically irreversible fouling index (HIFI) was proportional to the membrane pore size (r2=0.89) when the same feed water was filtrated. The UF membranes showed lower HIFI values than the MF membranes. Pore narrowing (internal fouling) was found to be a main fouling pattern of the hydraulically irreversible fouling. The internal fouling was caused by monolayer adsorption of foulants with different sizes that is dependent on the size of the membrane pore.

  20. Hydraulically irreversible fouling on ceramic MF/UF membranes: comparison of fouling indices, foulant composition and irreversible pore narrowing

    KAUST Repository

    Shang, Ran

    2015-05-06

    The application of ceramic membranes in water treatment is becoming increasing attractive because of their long life time and excellent chemical, mechanical and thermal stability. However, fouling of ceramic membranes, especially hydraulically irreversible fouling, is still a critical aspect affecting the operational cost and energy consumption in water treatment plants. In this study, four ceramic membranes with pore sizes or molecular weight cut-off (MWCO) of 0.20 μm, 0.14 μm, 300 kDa and 50 kDa were compared during natural surface water filtration with respect to hydraulically irreversible fouling index (HIFI), foulant composition and narrowing of pore size due to the irreversible fouling. Our results showed that the hydraulically irreversible fouling index (HIFI) was proportional to the membrane pore size (r2=0.89) when the same feed water was filtrated. The UF membranes showed lower HIFI values than the MF membranes. Pore narrowing (internal fouling) was found to be a main fouling pattern of the hydraulically irreversible fouling. The internal fouling was caused by monolayer adsorption of foulants with different sizes that is dependent on the size of the membrane pore.

  1. Irreversibility and dissipation in finite-state automata

    International Nuclear Information System (INIS)

    Ganesh, Natesh; Anderson, Neal G.

    2013-01-01

    Irreversibility and dissipation in finite-state automata (FSA) are considered from a physical-information-theoretic perspective. A quantitative measure for the computational irreversibility of finite automata is introduced, and a fundamental lower bound on the average energy dissipated per state transition is obtained and expressed in terms of FSA irreversibility. The irreversibility measure and energy bound are germane to any realization of a deterministic automaton that faithfully registers abstract FSA states in distinguishable states of a physical system coupled to a thermal environment, and that evolves via a sequence of interactions with an external system holding a physical instantiation of a random input string. The central result, which is shown to follow from quantum dynamics and entropic inequalities alone, can be regarded as a generalization of Landauer's Principle applicable to FSAs and tailorable to specified automata. Application to a simple FSA is illustrated.

  2. Extended Irreversible Thermodynamics

    CERN Document Server

    Jou, David

    2010-01-01

    This is the 4th edition of the highly acclaimed monograph on Extended Irreversible Thermodynamics, a theory that goes beyond the classical theory of irreversible processes. In contrast to the classical approach, the basic variables describing the system are complemented by non-equilibrium quantities. The claims made for extended thermodynamics are confirmed by the kinetic theory of gases and statistical mechanics. The book covers a wide spectrum of applications, and also contains a thorough discussion of the foundations and the scope of the current theories on non-equilibrium thermodynamics. For this new edition, the authors critically revised existing material while taking into account the most recent developments in fast moving fields such as heat transport in micro- and nanosystems or fast solidification fronts in materials sciences. Several fundamental chapters have been revisited emphasizing physics and applications over mathematical derivations. Also, fundamental questions on the definition of non-equil...

  3. Performance analysis of irreversible molten carbonate fuel cell – Braysson heat engine with ecological objective approach

    International Nuclear Information System (INIS)

    Açıkkalp, Emin

    2017-01-01

    Highlights: • An irreversible MCFC - Braysson heat engine is considered. • Its performance is investigated with ecological approach. • A new ecological criteria are presented called as modified ecological function. • Result are obtained numerically and discussed. - Abstract: An irreversible hybrid molten carbonate fuel cell-Braysson heat engine is taken into account. Basic thermodynamics parameters including power output, efficiency and exergy destruction rate are considered. In addition ecological function and new criteria, which is based on ecological function, for heat engines called as modified ecological function is suggested. Optimum conditions for mentioned parameters above are determined. Numerical results are obtained and plotted. Finally, results are discussed.

  4. Generalized irreversible heat-engine experiencing a complex heat-transfer law

    International Nuclear Information System (INIS)

    Chen Lingen; Li Jun; Sun Fengrui

    2008-01-01

    The fundamental optimal relation between optimal power-output and efficiency of a generalized irreversible Carnot heat-engine is derived based on a generalized heat-transfer law, including a generalized convective heat-transfer law and a generalized radiative heat-transfer law, q ∝ (ΔT n ) m . The generalized irreversible Carnot-engine model incorporates several internal and external irreversibilities, such as heat resistance, bypass heat-leak, friction, turbulence and other undesirable irreversibility factors. The added irreversibilities, besides heat resistance, are characterized by a constant parameter and a constant coefficient. The effects of heat-transfer laws and various loss terms are analyzed. The results obtained corroborate those in the literature

  5. Absorption media for irreversibly gettering thionyl chloride

    Science.gov (United States)

    Buffleben, George; Goods, Steven H.; Shepodd, Timothy; Wheeler, David R.; Whinnery, Jr., LeRoy

    2002-01-01

    Thionyl chloride is a hazardous and reactive chemical used as the liquid cathode in commercial primary batteries. Contrary to previous thinking, ASZM-TEDA.RTM. carbon (Calgon Corporation) reversibly absorbs thionyl chloride. Thus, several candidate materials were examined as irreversible getters for thionyl chloride. The capacity, rate and effect of temperature were also explored. A wide variety of likely materials were investigated through screening experiments focusing on the degree of heat generated by the reaction as well as the material absorption capacity and irreversibility, in order to help narrow the group of possible getter choices. More thorough, quantitative measurements were performed on promising materials. The best performing getter was a mixture of ZnO and ASZM-TEDA.RTM. carbon. In this example, the ZnO reacts with thionyl chloride to form ZnCl.sub.2 and SO.sub.2. The SO.sub.2 is then irreversibly gettered by ASZM-TEDA.RTM. carbon. This combination of ZnO and carbon has a high capacity, is irreversible and functions effectively above -20.degree. C.

  6. The Value of Fighting Irreversible Demise by Softening the Irreversible Cost

    NARCIS (Netherlands)

    Magis, P.; Sbuelz, A.

    2005-01-01

    We study a novel issue in the real-options-based technology innovation literature by means of double barrier contingent claims analysis.We show how much a ¯rm with the monopoly over a project is willing to spend in investment technology innovation that softens the irreversible cost of accessing the

  7. Irreversibility analysis for optimization design of plate fin heat exchangers using a multi-objective cuckoo search algorithm

    International Nuclear Information System (INIS)

    Wang, Zhe; Li, Yanzhong

    2015-01-01

    Highlights: • The first application of IMOCS for plate-fin heat exchanger design. • Irreversibility degrees of heat transfer and fluid friction are minimized. • Trade-off of efficiency, total cost and pumping power is achieved. • Both EGM and EDM methods have been compared in the optimization of PFHE. • This study has superiority over other single-objective optimization design. - Abstract: This paper introduces and applies an improved multi-objective cuckoo search (IMOCS) algorithm, a novel met-heuristic optimization algorithm based on cuckoo breeding behavior, for the multi-objective optimization design of plate-fin heat exchangers (PFHEs). A modified irreversibility degree of the PFHE is separated into heat transfer and fluid friction irreversibility degrees which are adopted as two initial objective functions to be minimized simultaneously for narrowing the search scope of the design. The maximization efficiency, minimization of pumping power, and total annual cost are considered final objective functions. Results obtained from a two dimensional normalized Pareto-optimal frontier clearly demonstrate the trade-off between heat transfer and fluid friction irreversibility. Moreover, a three dimensional Pareto-optimal frontier reveals a relationship between efficiency, total annual cost, and pumping power in the PFHE design. Three examples presented here further demonstrate that the presented method is able to obtain optimum solutions with higher accuracy, lower irreversibility, and fewer iterations as compared to the previous methods and single-objective design approaches

  8. Irreversible work in a thermal medium with colored noise

    International Nuclear Information System (INIS)

    Ohkuma, Takahiro

    2009-01-01

    Irreversible work and its fluctuations in a classical system governed by non-Markovian stochastic dynamics are investigated. The production of irreversible work depends not only on the protocol of an operation but also on the details of the non-Markovian memory. We consider a generalized Langevin equation with a memory kernel and derive an expression for the irreversible work in the case of slow operations by carrying out an expansion of this memory kernel in the parameter representing the length of the memory. We apply our formulation to a harmonically trapped system and demonstrate the efficiency of a cycle by evaluating the irreversible work. It is found that a decrease in the irreversible work due to the memory effect can occur for an operation through which the trap is squeezed. The results for this harmonic system are verified exactly in the case that the memory kernel has exponential decay

  9. Irreversible work in a thermal medium with colored noise

    Science.gov (United States)

    Ohkuma, Takahiro

    2009-10-01

    Irreversible work and its fluctuations in a classical system governed by non-Markovian stochastic dynamics are investigated. The production of irreversible work depends not only on the protocol of an operation but also on the details of the non-Markovian memory. We consider a generalized Langevin equation with a memory kernel and derive an expression for the irreversible work in the case of slow operations by carrying out an expansion of this memory kernel in the parameter representing the length of the memory. We apply our formulation to a harmonically trapped system and demonstrate the efficiency of a cycle by evaluating the irreversible work. It is found that a decrease in the irreversible work due to the memory effect can occur for an operation through which the trap is squeezed. The results for this harmonic system are verified exactly in the case that the memory kernel has exponential decay.

  10. Exergetic efficiency optimization for an irreversible heat pump ...

    Indian Academy of Sciences (India)

    side ... For irreversible cycle, the internal irreversibility, i.e., non-isentropic losses in the ... constant thermal capacitance rate (the product of mass flow rate and specific heat), .... reversed Brayton cycle is dependent on the external heat transfer ...

  11. The detection of local irreversibility in time series based on segmentation

    Science.gov (United States)

    Teng, Yue; Shang, Pengjian

    2018-06-01

    We propose a strategy for the detection of local irreversibility in stationary time series based on multiple scale. The detection is beneficial to evaluate the displacement of irreversibility toward local skewness. By means of this method, we can availably discuss the local irreversible fluctuations of time series as the scale changes. The method was applied to simulated nonlinear signals generated by the ARFIMA process and logistic map to show how the irreversibility functions react to the increasing of the multiple scale. The method was applied also to series of financial markets i.e., American, Chinese and European markets. The local irreversibility for different markets demonstrate distinct characteristics. Simulations and real data support the need of exploring local irreversibility.

  12. Linear Dimensional Stability of Irreversible Hydrocolloid Materials Over Time.

    Science.gov (United States)

    Garrofé, Analía B; Ferrari, Beatriz A; Picca, Mariana; Kaplan, Andrea E

    2015-12-01

    The aim of this study was to evaluate the linear dimensional stability of different irreversible hydrocolloid materials over time. A metal mold was designed with custom trays made of thermoplastic sheets (Sabilex, sheets 0.125 mm thick). Perforations were made in order to improve retention of the material. Five impressions were taken with each of the following: Kromopan 100 (LASCOD) [AlKr], which has dimensional stability of 100 hours, and Phase Plus (ZHERMACK) [AlPh], which has dimensional stability of 48 hours. Standardized digital photographs were taken at different time intervals (0, 15, 30, 45, 60, 120 minutes; 12, 24 and 96 hours), using an "ad-hoc" device. The images were analyzed with software (UTHSCSA Image Tool) by measuring the distance between intersection of the lines previously made at the top of the mold. The results were analyzed by ANOVA for repeated measures. Initial and final values were (mean and standard deviation): AlKr: 16.44 (0.22) and 16.34 (0.11), AlPh: 16.40 (0.06) and 16.18 (0.06). Statistical evaluation showed significant effect of material and time factors. Under the conditions in this study, time significantly affects the linear dimensional stability of irreversible hydrocolloid materials. Sociedad Argentina de Investigación Odontológica.

  13. Application of exergetic sustainability index to a nano-scale irreversible Brayton cycle operating with ideal Bose and Fermi gasses

    Energy Technology Data Exchange (ETDEWEB)

    Açıkkalp, Emin, E-mail: eacikkalp@gmail.com [Department of Mechanical and Manufacturing Engineering, Engineering Faculty, Bilecik S.E. University, Bilecik (Turkey); Caner, Necmettin [Department of Chemistry, Faculty of Arts and Sciences, Eskisehir Osmangazi University, Eskisehir (Turkey)

    2015-09-25

    Highlights: • An irreversible Brayton cycle operating quantum gasses is considered. • Exergetic sustainability index is derived for nano-scale cycles. • Nano-scale effects are considered. • Calculation are conducted for irreversible cycles. • Numerical results are presented and discussed. - Abstract: In this study, a nano-scale irreversible Brayton cycle operating with quantum gasses including Bose and Fermi gasses is researched. Developments in the nano-technology cause searching the nano-scale machines including thermal systems to be unavoidable. Thermodynamic analysis of a nano-scale irreversible Brayton cycle operating with Bose and Fermi gasses was performed (especially using exergetic sustainability index). In addition, thermodynamic analysis involving classical evaluation parameters such as work output, exergy output, entropy generation, energy and exergy efficiencies were conducted. Results are submitted numerically and finally some useful recommendations were conducted. Some important results are: entropy generation and exergetic sustainability index are affected mostly for Bose gas and power output and exergy output are affected mostly for the Fermi gas by x. At the high temperature conditions, work output and entropy generation have high values comparing with other degeneracy conditions.

  14. Noun Countability; Count Nouns and Non-count Nouns, What are the Syntactic Differences Between them?

    Directory of Open Access Journals (Sweden)

    Azhar A. Alkazwini

    2016-11-01

    Full Text Available Words that function as the subjects of verbs, objects of verbs or prepositions and which can have a plural form and possessive ending are known as nouns. They are described as referring to persons, places, things, states, or qualities and might also be used as an attributive modifier. In this paper, classes and subclasses of nouns shall be presented, then, noun countability branching into count and non-count nous shall be discussed. A number of present examples illustrating differences between count and non-count nouns and this includes determiner-head-co-occurrence restrictions of number, subject-verb agreement, in addition to some exceptions to this agreement rule shall be discussed. Also, the lexically inherent number in nouns and how inherently plural nouns are classified in terms of (+/- count are illustrated. This research will discuss partitive construction of count and non-count nouns, nouns as attributive modifier and, finally, conclude with the fact that there are syntactic difference between count and non-count in the English Language.

  15. General thermodynamic performance of irreversible absorption heat pump

    International Nuclear Information System (INIS)

    Zhao Xiling; Fu Lin; Zhang Shigang

    2011-01-01

    The absorption heat pump (AHP) was studied with thermodynamics. A four reservoirs model of absorption heat pump was established considering the heat resistance, heat leak and the internal irreversibility. The reasonable working regions, the performance effects of irreversibility, heat leak and the correlation of four components were studied. When studying the effects of internal irreversibility, two internal irreversibility parameters (I he for generator-absorber assembly and I re for evaporator-condenser assembly) were introduced to distinguish the different effects. When studying the heat transfer relations of four components, a universal relationship between the main parameters were deduced. The results which have more realized meaning show that, the reduction of the friction, heat loss, and internal dissipations of the evaporator-condenser assembly are more important than its reduction of generator-absorber assembly, and lessening the heat leak of generator are more important than its reduction of other components to improve the AHP performance.

  16. Stochastic dynamics and irreversibility

    CERN Document Server

    Tomé, Tânia

    2015-01-01

    This textbook presents an exposition of stochastic dynamics and irreversibility. It comprises the principles of probability theory and the stochastic dynamics in continuous spaces, described by Langevin and Fokker-Planck equations, and in discrete spaces, described by Markov chains and master equations. Special concern is given to the study of irreversibility, both in systems that evolve to equilibrium and in nonequilibrium stationary states. Attention is also given to the study of models displaying phase transitions and critical phenomema both in thermodynamic equilibrium and out of equilibrium. These models include the linear Glauber model, the Glauber-Ising model, lattice models with absorbing states such as the contact process and those used in population dynamic and spreading of epidemic, probabilistic cellular automata, reaction-diffusion processes, random sequential adsorption and dynamic percolation. A stochastic approach to chemical reaction is also presented.The textbook is intended for students of ...

  17. Irreversible thermodynamics of Poisson processes with reaction.

    Science.gov (United States)

    Méndez, V; Fort, J

    1999-11-01

    A kinetic model is derived to study the successive movements of particles, described by a Poisson process, as well as their generation. The irreversible thermodynamics of this system is also studied from the kinetic model. This makes it possible to evaluate the differences between thermodynamical quantities computed exactly and up to second-order. Such differences determine the range of validity of the second-order approximation to extended irreversible thermodynamics.

  18. Thermodynamic Analysis of an Irreversible Maisotsenko Reciprocating Brayton Cycle

    Directory of Open Access Journals (Sweden)

    Fuli Zhu

    2018-03-01

    Full Text Available An irreversible Maisotsenko reciprocating Brayton cycle (MRBC model is established using the finite time thermodynamic (FTT theory and taking the heat transfer loss (HTL, piston friction loss (PFL, and internal irreversible losses (IILs into consideration in this paper. A calculation flowchart of the power output (P and efficiency (η of the cycle is provided, and the effects of the mass flow rate (MFR of the injection of water to the cycle and some other design parameters on the performance of cycle are analyzed by detailed numerical examples. Furthermore, the superiority of irreversible MRBC is verified as the cycle and is compared with the traditional irreversible reciprocating Brayton cycle (RBC. The results can provide certain theoretical guiding significance for the optimal design of practical Maisotsenko reciprocating gas turbine plants.

  19. Antibiotic use for irreversible pulpitis.

    Science.gov (United States)

    Agnihotry, Anirudha; Fedorowicz, Zbys; van Zuuren, Esther J; Farman, Allan G; Al-Langawi, Jassim Hasan

    2016-02-17

    Irreversible pulpitis, which is characterised by acute and intense pain, is one of the most frequent reasons that patients attend for emergency dental care. Apart from removal of the tooth, the customary way of relieving the pain of irreversible pulpitis is by drilling into the tooth, removing the inflamed pulp (nerve) and cleaning the root canal. However, a significant number of dentists continue to prescribe antibiotics to stop the pain of irreversible pulpitis.This review updates the previous version published in 2013. To assess the effects of systemic antibiotics for irreversible pulpitis. We searched the Cochrane Oral Health Group's Trials Register (to 27 January 2016); the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2015, Issue 12); MEDLINE via Ovid (1946 to 27 January 2016); EMBASE via Ovid (1980 to 27 January 2016), ClinicalTrials.gov (to 27 January 2016) and the WHO International Clinical Trials Registry Platform (to 27 January 2016). There were no language restrictions in the searches of the electronic databases. Randomised controlled trials which compared pain relief with systemic antibiotics and analgesics, against placebo and analgesics in the acute preoperative phase of irreversible pulpitis. Two review authors screened studies and extracted data independently. We assessed the quality of the evidence of included studies using GRADEpro software. Pooling of data was not possible and a descriptive summary is presented. One trial assessed at low risk of bias, involving 40 participants was included in this update of the review. The quality of the body of evidence was rated low for the different outcomes. There was a close parallel distribution of the pain ratings in both the intervention and placebo groups over the seven-day study period. There was insufficient evidence to claim or refute a benefit for penicillin for pain intensity. There was no significant difference in the mean total number of ibuprofen tablets over the

  20. Optimization of an irreversible Stirling regenerative cycle

    International Nuclear Information System (INIS)

    Aragón-González, G; Cano-Bianco, M; León-Galicia, A; Rivera-Camacho, J M

    2015-01-01

    In this work a Stirling regenerative cycle with some irreversibilities is analyzed. The analyzed irreversibilities are located at the heat exchangers. They receive a finite amount of heat and heat leakage occurs between both reservoirs. Using this model, power and the efficiency at maximum power are obtained. Some optimal design parameters for the exchanger heat areas and thermal conductances are presented. The relation between the power, efficiency and the results obtained are shown graphically

  1. Reversible and irreversible heat engine and refrigerator cycles

    Science.gov (United States)

    Leff, Harvey S.

    2018-05-01

    Although no reversible thermodynamic cycles exist in nature, nearly all cycles covered in textbooks are reversible. This is a review, clarification, and extension of results and concepts for quasistatic, reversible and irreversible processes and cycles, intended primarily for teachers and students. Distinctions between the latter process types are explained, with emphasis on clockwise (CW) and counterclockwise (CCW) cycles. Specific examples of each are examined, including Carnot, Kelvin and Stirling cycles. For the Stirling cycle, potentially useful task-specific efficiency measures are proposed and illustrated. Whether a cycle behaves as a traditional refrigerator or heat engine can depend on whether it is reversible or irreversible. Reversible and irreversible-quasistatic CW cycles both satisfy Carnot's inequality for thermal efficiency, η ≤ η C a r n o t . Irreversible CCW cycles with two reservoirs satisfy the coefficient of performance inequality K ≤ K C a r n o t . However, an arbitrary reversible cycle satisfies K ≥ K C a r n o t when compared with a reversible Carnot cycle operating between its maximum and minimum temperatures, a potentially counterintuitive result.

  2. Formation of Irreversible H-bonds in Cellulose Materials

    Science.gov (United States)

    Umesh P. Agarwal; Sally A. Ralph; Rick S. Reiner; Nicole M. Stark

    2015-01-01

    Understanding of formation of irreversible Hbonds in cellulose is important in a number of fields. For example, fields as diverse as pulp and paper and enzymatic saccharification of cellulose are affected. In the present investigation, the phenomenon of formation of irreversible H-bonds is studied in a variety of celluloses and under two different drying conditions....

  3. Irreversible climate change due to carbon dioxide emissions

    Science.gov (United States)

    Solomon, Susan; Plattner, Gian-Kasper; Knutti, Reto; Friedlingstein, Pierre

    2009-01-01

    The severity of damaging human-induced climate change depends not only on the magnitude of the change but also on the potential for irreversibility. This paper shows that the climate change that takes place due to increases in carbon dioxide concentration is largely irreversible for 1,000 years after emissions stop. Following cessation of emissions, removal of atmospheric carbon dioxide decreases radiative forcing, but is largely compensated by slower loss of heat to the ocean, so that atmospheric temperatures do not drop significantly for at least 1,000 years. Among illustrative irreversible impacts that should be expected if atmospheric carbon dioxide concentrations increase from current levels near 385 parts per million by volume (ppmv) to a peak of 450–600 ppmv over the coming century are irreversible dry-season rainfall reductions in several regions comparable to those of the “dust bowl” era and inexorable sea level rise. Thermal expansion of the warming ocean provides a conservative lower limit to irreversible global average sea level rise of at least 0.4–1.0 m if 21st century CO2 concentrations exceed 600 ppmv and 0.6–1.9 m for peak CO2 concentrations exceeding ≈1,000 ppmv. Additional contributions from glaciers and ice sheet contributions to future sea level rise are uncertain but may equal or exceed several meters over the next millennium or longer. PMID:19179281

  4. Intrinsic irreversibility in quantum theory

    International Nuclear Information System (INIS)

    Prigogine, I.; Petrosky, T.Y.

    1987-01-01

    Quantum theory has a dual structure: while solutions of the Schroedinger equation evolve in a deterministic and time reversible way, measurement introduces irreversibility and stochasticity. This presents a contrast to Bohr-Sommerfeld-Einstein theory, in which transitions between quantum states are associated with spontaneous and induced transitions, defined in terms of stochastic processes. A new form of quantum theory is presented here, which contains an intrinsic form of irreversibility, independent of observation. This new form applies to situations corresponding to a continuous spectrum and to quantum states with finite life time. The usual non-commutative algebra associated to quantum theory is replaced by more general algebra, in which operators are also non-distributive. Our approach leads to a number of predictions, which hopefully may be verified or refuted in the next years. (orig.)

  5. Irreversibility and self-organization in spin glasses. 2. Irreversibility and the problem of configuration averaging

    International Nuclear Information System (INIS)

    Kovrov, V.P.; Kurbatov, A.M.

    1989-05-01

    The generalization of a configuration averaging to a system displaying irreversible effects is suggested. The properties of the ''pathological'' equilibrium state at low temperatures are determined and discussed. (author). 16 refs, 3 figs

  6. Chemical kinetics, stochastic processes, and irreversible thermodynamics

    CERN Document Server

    Santillán, Moisés

    2014-01-01

    This book brings theories in nonlinear dynamics, stochastic processes, irreversible thermodynamics, physical chemistry, and biochemistry together in an introductory but formal and comprehensive manner.  Coupled with examples, the theories are developed stepwise, starting with the simplest concepts and building upon them into a more general framework.  Furthermore, each new mathematical derivation is immediately applied to one or more biological systems.  The last chapters focus on applying mathematical and physical techniques to study systems such as: gene regulatory networks and ion channels. The target audience of this book are mainly final year undergraduate and graduate students with a solid mathematical background (physicists, mathematicians, and engineers), as well as with basic notions of biochemistry and cellular biology.  This book can also be useful to students with a biological background who are interested in mathematical modeling, and have a working knowledge of calculus, differential equatio...

  7. Optimization at different loads by minimization of irreversibilities

    International Nuclear Information System (INIS)

    Wong, K.F.V.; Niu, Z.

    1991-01-01

    This paper reports that the irreversibility of the power cycle was chosen as the objective function as this function can successfully measure both the quality and quantity of energy flow in the cycle. Minimization of the irreversibility ensures that the power cycle will operate more efficiently. One feature of the present work is that the boiler, turbine, condenser and heaters are treated as one system for the purpose of optimization. In the optimization model, nine regression formulae are used, which are obtained from the measured test data. From the results of the present work, it can be seen that the optimization model developed can represent the effect of operational parameters on the power plant first and second law efficiency. Some of the results can be used to provide guidance for the optimal operation of the power plant. When the power cycle works at full load, the main steam temperature and pressure should be at the upper limit for minimal irreversibility of the system. If the load is less than 65% of its design capacity, the steam temperature and pressure should be decreased for a lower irreversibility of the system

  8. Conducts of disinfection, pouring and storage of irreversible hydrocolloid impressions by undergraduate students

    Directory of Open Access Journals (Sweden)

    Thalisson Saymo de Oliveira SILVA

    Full Text Available Abstract Introduction Obtaining dental models that accurately represent the molded oral tissue requires professional attention, especially when using irreversible hydrocolloid as a molding material. Objective To evaluate the conducts of undergraduate dental students at different internships for the disinfecting procedures, pouring, and storage of irreversible hydrocolloid impressions. Material and method This is an observational, cross-sectional and descriptive study with a census sample of 89 students enrolled in the supervised internships I, II, III and IV. Data collection was performed using a structured questionnaire containing eight questions. Data were analyzed at the 5% significance level. Result Most of the students (88.8% performed the disinfection procedure, for which the most widely used method (64.6% was the application of sodium hypochlorite 1% spray stored in a sealed container. The most common disinfection time was 10 minutes (86.1%. Students in the early internships performed better in regard to the proportion of water/plaster to be used compared with students in the final internships. At all internships, pouring and storage of the ensemble of mold and model were neglected during the setting reaction. There was a statistically significant association between the stage and the disinfection method, the ratio of water/powder and pouring of the model (p<0.05. Conclusion Students exhibited appropriate conduct of disinfection; however, they should be encouraged to use evidence-based clinical practices in order to improve the procedures of pouring and storage of irreversible hydrocolloid molds.

  9. IRREVERSIBILITY GENERATION IN SUGAR, ALCOHOL AND BIOGAS INTEGRATED PRODUCTIONS

    Directory of Open Access Journals (Sweden)

    Meilyn González Cortés

    2017-01-01

    Full Text Available In this work, the stages of losses and lower exergetic efficiency are determined when the sugar production process is integrated with others for the production of products such as biogas, torula yeast and electricity. The study is carried out in three scenarios of integrated processes for obtaining the indicated products. A sugar factory in which sugar and electricity are produced is considered as the base scenario and from this; a second scenario is inferred in which alcohol is produced from the molasses of the sugar process and biogas from the vinasse of the alcohol distillation process. Finally, a third scenario is exergetically evaluated in which sugar, electricity, biogas and alcohol are produced, but this last one from juices and molasses of the sugar process. For the exergetic analysis the integrated scheme was divided into 8 subsystems. From the analysis of results, the major subsystems that generate irreversibilities are: cogeneration (64.36-65.98%, juice extraction (8.85-9.85%, crystallization and cooking, (8.48 -9.02%, fermentation (4.12-4.94% and distillation (2.74-3.2%. Improvements are proposed to minimize irreversibilities, including the thermal integration of processes, technological modifications in the fermentation process and the introduction of more efficient equipment for the generation of electricity. The exergetic efficiency is between 78.95-81.10%, obtaining greater exergetic efficiency in the scheme of joint operation to produce sugar, alcohol and biogas.

  10. Substance P and CGRP expression in dental pulps with irreversible pulpitis.

    Science.gov (United States)

    Sattari, Mandana; Mozayeni, Mohammad Ali; Matloob, Arash; Mozayeni, Maryam; Javaheri, Homan H

    2010-08-01

    The purpose of this study was to compare substance P (SP) and calcitonin gene-related peptide (CGRP) expression in pulp tissue with clinically diagnosed symptomatic and asymptomatic irreversible pulpitis. Healthy pulps acted as controls. Five normal pulps and 40 with irreversible pulpitis (20 symptomatic and 20 asymptomatic) were obtained from 45 different patients. SP and CGRP expression was determined by competition binding assays using enzyme immunoassay. anova and Mann-Whitney tests were used to ascertain if there were statistically significant differences between the groups. The results showed that neuropeptides were found in all pulp samples. The highest and the lowest expressions for SP and CGRP were found in symptomatic irreversible pulpitis and healthy pulps groups, respectively. The differences between healthy pulps and the groups of pulps having irreversible pulpitis were significant (P pulpitis groups (P pulpitis groups were not significant. This study demonstrated that the expression of CGRP and SP is significantly higher in pulps with irreversible pulpitis compared with healthy pulps.

  11. Concerning the study of the irreversible magnetic behaviour of superconductivity; Contribution a l'etude du comportement magnetique irreversible des supraconducteurs

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, G [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-03-01

    The influence of the presence of extended lattice defects on the magnetic behaviour has been studied for the case of type I superconductors, such as Re and Ta, and in a more quantitative manner for the type II superconductor niobium. In this case, measurements of the thermal conductivity have given an estimate of the relative concentration of lattice defects in each specimen. These measurements show that the larger the number of lattice defects, the more irreversible becomes the magnetization curve, and the larger becomes the values of the critical current, which is related by a simple model to the magnetization values. Finally, a study by transmission electron microscopy has confirmed on the one hand the diversity of the extended lattice defects and on the other hand has allowed the formulation of several hypothesis on their respective influence. [French] L'influence de la presence de defauts etendus sur le comportement magnetique a ete etudie pour des supraconducteurs de premiere espece, tels que le rhenium et le tantale, et plus quantitativement pour un supraconducteur de deuxieme espece, le niobium. Dans ce cas, des mesures de conductibilite thermique ont permis d'estimer la concentration relative des defauts du reseau dans chaque echantillon. Ces mesures montrent que plus les defauts du reseau sont nombreux, plus la courbe d'aimantation est irreversible, et plus les valeurs du courant critique, reliees par un modele simple aux valeurs de l'aimantation, sont elevees. Enfin une etude par microscopie electronique en transmission - a permis d'une part de constater la diversite des defauts etendus et d'autre part de formuler quelques hypotheses sur leurs influences respectives.

  12. Guinea pig ductus arteriosus. II - Irreversible closure after birth.

    Science.gov (United States)

    Fay, F. S.; Cooke, P. H.

    1972-01-01

    To investigate the mechanism underlying irreversibility of ductal closure after birth, studies were undertaken to determine the exact time course for the onset of irreversible closure of the guinea pig ductus arteriosus. Parallel studies of the reactivity of ductal smooth muscle to oxygen and studies of the postpartum cellular changes within the vessel were also carried out.

  13. Multiscale time irreversibility of heart rate and blood pressure variability during orthostasis

    International Nuclear Information System (INIS)

    Chladekova, L; Czippelova, B; Turianikova, Z; Tonhajzerova, I; Calkovska, A; Javorka, M; Baumert, M

    2012-01-01

    Time irreversibility is a characteristic feature of non-equilibrium, complex systems such as the cardiovascular control mediated by the autonomic nervous system (ANS). Time irreversibility analysis of heart rate variability (HRV) and blood pressure variability (BPV) represents a new approach to assess cardiovascular regulatory mechanisms. The aim of this paper was to assess the changes in HRV and BPV irreversibility during the active orthostatic test (a balance of ANS shifted towards sympathetic predominance) in 28 healthy young subjects. We used three different time irreversibility indices—Porta’s, Guzik's and Ehler's indices (P%, G% and E, respectively) derived from data segments containing 1000 beat-to-beat intervals on four timescales. We observed an increase in the HRV and a decrease in the BPV irreversibility during standing compared to the supine position. The postural change in irreversibility was confirmed by surrogate data analysis. The differences were more evident in G% and E than P% and for higher scale factors. Statistical analysis showed a close relationship between G% and E. Contrary to this, the association between P% and G% and P% and E was not proven. We conclude that time irreversibility of beat-to-beat HRV and BPV is significantly altered during orthostasis, implicating involvement of the autonomous nervous system in its generation. (paper)

  14. Irreversibility and conditional probability

    International Nuclear Information System (INIS)

    Stuart, C.I.J.M.

    1989-01-01

    The mathematical entropy - unlike physical entropy - is simply a measure of uniformity for probability distributions in general. So understood, conditional entropies have the same logical structure as conditional probabilities. If, as is sometimes supposed, conditional probabilities are time-reversible, then so are conditional entropies and, paradoxically, both then share this symmetry with physical equations of motion. The paradox is, of course that probabilities yield a direction to time both in statistical mechanics and quantum mechanics, while the equations of motion do not. The supposed time-reversibility of both conditionals seems also to involve a form of retrocausality that is related to, but possibly not the same as, that described by Costa de Beaurgard. The retrocausality is paradoxically at odds with the generally presumed irreversibility of the quantum mechanical measurement process. Further paradox emerges if the supposed time-reversibility of the conditionals is linked with the idea that the thermodynamic entropy is the same thing as 'missing information' since this confounds the thermodynamic and mathematical entropies. However, it is shown that irreversibility is a formal consequence of conditional entropies and, hence, of conditional probabilities also. 8 refs. (Author)

  15. Performance Optimization of Irreversible Air Heat Pumps Considering Size Effect

    Science.gov (United States)

    Bi, Yuehong; Chen, Lingen; Ding, Zemin; Sun, Fengrui

    2018-06-01

    Considering the size of an irreversible air heat pump (AHP), heating load density (HLD) is taken as thermodynamic optimization objective by using finite-time thermodynamics. Based on an irreversible AHP with infinite reservoir thermal-capacitance rate model, the expression of HLD of AHP is put forward. The HLD optimization processes are studied analytically and numerically, which consist of two aspects: (1) to choose pressure ratio; (2) to distribute heat-exchanger inventory. Heat reservoir temperatures, heat transfer performance of heat exchangers as well as irreversibility during compression and expansion processes are important factors influencing on the performance of an irreversible AHP, which are characterized with temperature ratio, heat exchanger inventory as well as isentropic efficiencies, respectively. Those impacts of parameters on the maximum HLD are thoroughly studied. The research results show that HLD optimization can make the size of the AHP system smaller and improve the compactness of system.

  16. Kinetic theory of nonequilibrium ensembles, irreversible thermodynamics, and generalized hydrodynamics

    CERN Document Server

    Eu, Byung Chan

    2016-01-01

    This book presents the fundamentals of irreversible thermodynamics for nonlinear transport processes in gases and liquids, as well as for generalized hydrodynamics extending the classical hydrodynamics of Navier, Stokes, Fourier, and Fick. Together with its companion volume on relativistic theories, it provides a comprehensive picture of the kinetic theory formulated from the viewpoint of nonequilibrium ensembles in both nonrelativistic and, in Vol. 2, relativistic contexts. Theories of macroscopic irreversible processes must strictly conform to the thermodynamic laws at every step and in all approximations that enter their derivation from the mechanical principles. Upholding this as the inviolable tenet, the author develops theories of irreversible transport processes in fluids (gases or liquids) on the basis of irreversible kinetic equations satisfying the H theorem. They apply regardless of whether the processes are near to or far removed from equilibrium, or whether they are linear or nonlinear with respe...

  17. Transition to Clean Capital, Irreversible Investment and Stranded Assets

    OpenAIRE

    Rozenberg, Julie; Vogt-Schilb, Adrien; Hallegatte, Stephane

    2014-01-01

    This paper uses a Ramsey model with two types of capital to analyze the optimal transition to clean capital when polluting investment is irreversible. The cost of climate mitigation decomposes as a technical cost of using clean instead of polluting capital and a transition cost from the irreversibility of pre-existing polluting capital. With a carbon price, the transition cost can be limit...

  18. Spectral line intensity irreversibility in circulatory plasma magnetization processes

    Science.gov (United States)

    Qu, Z. Q.; Dun, G. T.

    2012-01-01

    Spectral line intensity variation is found to be irreversible in circulatory plasma magnetization process by experiments described in this paper, i.e., the curves illustrating spectral line photon fluxes irradiated from a light source immerged in a magnetic field by increasing the magnetic induction cannot be reproduced by decreasing the magnetic induction within the errors. There are two plasma magnetization patterns found. One shows that the intensities are greater at the same magnetic inductions during the magnetic induction decreasing process after the increasing, and the other gives the opposite effect. This reveals that the magneto-induced excitation and de-excitation process is irreversible like ferromagnetic magnetization. But the two irreversible processes are very different in many aspects stated in the text.

  19. Ecological optimization and parametric study of irreversible Stirling and Ericsson heat pumps

    International Nuclear Information System (INIS)

    Tyagi, S.K.; Kaushik, S.C.; Salohtra, R.

    2002-01-01

    This communication presents the ecological optimization and parametric study of irreversible Stirling and Ericsson heat pump cycles, in which the external irreversibility is due to finite temperature difference between working fluid and external reservoirs while the internal irreversibilities are due to regenerative heat loss and other entropy generations within the cycle. The ecological function is defined as the heating load minus the irreversibility (power loss) which is ambient temperature times the entropy generation. The ecological function is optimized with respect to working fluid temperatures, and the expressions for various parameters at the optimal operating condition are obtained. The effects of different operating parameters on the performance of these cycles have been studied. It is found that the effect of internal irreversibility parameter is more pronounced than the other parameters on the performance of these cycles. (author)

  20. Ictal time-irreversible intracranial EEG signals as markers of the epileptogenic zone.

    Science.gov (United States)

    Schindler, Kaspar; Rummel, Christian; Andrzejak, Ralph G; Goodfellow, Marc; Zubler, Frédéric; Abela, Eugenio; Wiest, Roland; Pollo, Claudio; Steimer, Andreas; Gast, Heidemarie

    2016-09-01

    To show that time-irreversible EEG signals recorded with intracranial electrodes during seizures can serve as markers of the epileptogenic zone. We use the recently developed method of mapping time series into directed horizontal graphs (dHVG). Each node of the dHVG represents a time point in the original intracranial EEG (iEEG) signal. Statistically significant differences between the distributions of the nodes' number of input and output connections are used to detect time-irreversible iEEG signals. In 31 of 32 seizure recordings we found time-irreversible iEEG signals. The maximally time-irreversible signals always occurred during seizures, with highest probability in the middle of the first seizure half. These signals spanned a large range of frequencies and amplitudes but were all characterized by saw-tooth like shaped components. Brain regions removed from patients who became post-surgically seizure-free generated significantly larger time-irreversibilities than regions removed from patients who still had seizures after surgery. Our results corroborate that ictal time-irreversible iEEG signals can indeed serve as markers of the epileptogenic zone and can be efficiently detected and quantified in a time-resolved manner by dHVG based methods. Ictal time-irreversible EEG signals can help to improve pre-surgical evaluation in patients suffering from pharmaco-resistant epilepsies. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  1. Irreversible properties of YBCO coated conductors

    International Nuclear Information System (INIS)

    Vostner, A.

    2001-02-01

    Over the past few years substantial efforts were made to optimize the fabrication techniques of various high temperature superconductors for commercial applications. In addition to Bi-2223 tapes, Y-123 coated conductors have the potential for large-scale production and are considered as the second generation of superconducting 'wires' for high current applications. This work reports on magnetic and transport current investigations of Y-123 thick films deposited on either single crystalline substrates by liquid phase epitaxy (LPE) or on metallic substrates by pulsed laser deposition (PLD). At the beginning, a short introduction of the general idea of a coated conductor and of the different production techniques is presented, followed by a description of the different experimental set-ups and the evaluation methods. The main part starts with the results obtained from SQUID magnetometry and ac-susceptibility measurements including the transition temperatures T c , the field dependence of the magnetic critical current densities and the irreversibility lines. In addition, some issues concerning the granular structure and the inter- and intragranular current distribution of the superconducting films are discussed. The investigations by transport currents are focused on the behavior of the application relevant irreversible parameters. These are the angular and the field dependence of the critical transport current densities at 77 and 60 K, as well as the temperature dependence of the irreversibility fields up to 6 T. To gain more insight into the defect structure of the films, neutron irradiation studies were performed on some samples. The introduction of these artificial pinning centers causes large enhancements of the magnetic J c in LPE specimens for the field parallel to the c-axis (H//c) at higher temperatures and magnetic fields. The granular structure of the samples does not change up to the highest neutron fluences. However, the enhancements of the transport J c

  2. Performance of an irreversible quantum Ericsson cooler at low temperature limit

    International Nuclear Information System (INIS)

    Wu Feng; Chen Lingen; Wu Shuang; Sun Fengrui

    2006-01-01

    The purpose of this paper is to investigate the effect of quantum properties of the working medium on the performance of an irreversible quantum Ericsson cooler with spin-1/2. The cooler is studied with the losses of heat resistance, heat leakage and internal irreversibility. The optimal relationship between the dimensionless cooling load R * versus the coefficient of performance ε for the irreversible quantum Ericsson cooler is derived. In particular, the performance characteristics of the cooler at the low temperature limit are discussed

  3. Reversible and Irreversible Binding of Nanoparticles to Polymeric Surfaces

    Directory of Open Access Journals (Sweden)

    Wolfgang H. Binder

    2009-01-01

    Full Text Available Reversible and irreversible binding of CdSe-nanoparticles and nanorods to polymeric surfaces via a strong, multiple hydrogen bond (= Hamilton-receptor/barbituric acid is described. Based on ROMP-copolymers, the supramolecular interaction on a thin polymer film is controlled by living polymerization methods, attaching the Hamilton-receptor in various architectures, and concentrations. Strong binding is observed with CdSe-nanoparticles and CdSe-nanorods, whose surfaces are equipped with matching barbituric acid-moieties. Addition of polar solvents, able to break the hydrogen bonds leads to the detachment of the nanoparticles from the polymeric film. Irreversible binding is observed if an azide/alkine-“click”-reaction is conducted after supramolecular recognition of the nanoparticles on the polymeric surface. Thus reversible or irreversible attachment of the nanosized objects can be achieved.

  4. Optimal allocation of thermodynamic irreversibility for the integrated design of propulsion and thermal management systems

    Science.gov (United States)

    Maser, Adam Charles

    work losses over the time history of the mission. The characterization of the thermodynamic irreversibility distribution helps give the propulsion systems designer an absolute and consistent view of the tradeoffs associated with the design of the entire integrated system. Consequently, this leads directly to the question of the proper allocation of irreversibility across each of the components. The process of searching for the most favorable allocation of this irreversibility is the central theme of the research and must take into account production cost and vehicle mission performance. The production cost element is accomplished by including an engine component weight and cost prediction capability within the system model. The vehicle mission performance is obtained by directly linking the propulsion and thermal management model to a vehicle performance model and flying it through a mission profile. A canonical propulsion and thermal management systems architecture is then presented to experimentally test each element of the methodology separately: first the integrated modeling and simulation, then the irreversibility, cost, and mission performance considerations, and then finally the proper technique to perform the optimal allocation. A goal of this research is the description of the optimal allocation of system irreversibility to enable an engine cycle design with improved performance and cost at the vehicle-level. To do this, a numerical optimization was first used to minimize system-level production and operating costs by fixing the performance requirements and identifying the best settings for all of the design variables. There are two major drawbacks to this approach: It does not allow the designer to directly trade off the performance requirements and it does not allow the individual component losses to directly factor into the optimization. An irreversibility allocation approach based on the economic concept of resource allocation is then compared to the

  5. The thermomechanics of nonlinear irreversible behaviors an introduction

    CERN Document Server

    Maugin, Gérard A

    1999-01-01

    In this invaluable book, macroscopic irreversible thermodynamics is presented in its realm and its splendor by appealing to the notion of internal variables of state. This applies to both fluids and solids with or without microstructures of mechanical or electromagnetic origin. This unmatched richness of essentially nonlinear behaviors is the result of the use of modern mathematical techniques such as convex analysis in a clear-cut framework which allows one to put under the umbrella of "irreversible thermodynamics" behaviors which until now have been commonly considered either not easily cove

  6. Irreversible Thermodynamics of the Universe: Constraints from Planck Data

    International Nuclear Information System (INIS)

    Saha, Subhajit; Chakraborty, Subenoy; Biswas, Atreyee

    2014-01-01

    The present work deals with irreversible universal thermodynamics. The homogenous and isotropic flat model of the universe is chosen as open thermodynamical system and nonequilibrium thermodynamics comes into picture. For simplicity, entropy flow is considered only due to heat conduction. Further, due to Maxwell-Cattaneo modified Fourier law for nonequilibrium phenomenon, the temperature satisfies damped wave equation instead of heat conduction equation. Validity of generalized second law of thermodynamics (GSLT) has been investigated for universe bounded by apparent or event horizon with cosmic substratum as perfect fluid with constant or variable equation of state or interacting dark species. Finally, we have used three Planck data sets to constrain the thermal conductivity λ and the coupling parameter b 2 . These constraints must be satisfied in order for GSLT to hold for universe bounded by apparent or event horizons

  7. Irreversibility and Action of the Heat Conduction Process

    Directory of Open Access Journals (Sweden)

    Yu-Chao Hua

    2018-03-01

    Full Text Available Irreversibility (that is, the “one-sidedness” of time of a physical process can be characterized by using Lyapunov functions in the modern theory of stability. In this theoretical framework, entropy and its production rate have been generally regarded as Lyapunov functions in order to measure the irreversibility of various physical processes. In fact, the Lyapunov function is not always unique. In the represent work, a rigorous proof is given that the entransy and its dissipation rate can also serve as Lyapunov functions associated with the irreversibility of the heat conduction process without the conversion between heat and work. In addition, the variation of the entransy dissipation rate can lead to Fourier’s heat conduction law, while the entropy production rate cannot. This shows that the entransy dissipation rate, rather than the entropy production rate, is the unique action for the heat conduction process, and can be used to establish the finite element method for the approximate solution of heat conduction problems and the optimization of heat transfer processes.

  8. Constructal theory through thermodynamics of irreversible processes framework

    International Nuclear Information System (INIS)

    Tescari, S.; Mazet, N.; Neveu, P.

    2011-01-01

    Highlights: → Point to area flow problem is solved through Thermodynamics of irreversible processes. → A new optimisation criterion is defined: the exergy or entropy impedance. → Optimisation is performed following two different routes, constructal or global. → Global optimisation is more efficient than constructal optimisation. → Global optimisation enhances the domain of construct benefits. - Abstract: Point to volume flow problem is revisited on a thermodynamics of irreversible processes (TIP) basis. The first step consists in evaluating the local entropy production of the system, and deducing from this expression the phenomenological laws. Then, the total entropy production can be simply evaluated. It is demonstrated that total entropy production can be written in a remarkable form: the product of the so-called entropy impedance with the square of the heat flux. As the heat flux is given, optimisation consists in minimising the entropy impedance. It is also shown that minimising entropy impedance minimises the maximum temperature difference. Applied to the elemental volume, this optimisation process leads to a shape factor close to the one already published. For the first construction, the equivalent system is defined as stated by Prigogine: when subjected to the same constraints, two systems are thermodynamically equivalent if their entropy production is equal. Two optimisation routes are then investigated: a global optimisation where all scales are taken into account and the constructal optimisation where the system is optimised scale by scale. In this second case, results are close to Ghodossi's work. When global optimisation is performed, it is demonstrated that conductive paths have to be spread uniformly in the active material (i.e. the number of elemental volumes must go to infinite). Comparing the two routes, global optimisation leads to better performance than constructal optimisation. Moreover, global optimisation enlarges the domain of

  9. A kinetic equation for irreversible aggregation

    International Nuclear Information System (INIS)

    Zanette, D.H.

    1990-09-01

    We introduce a kinetic equation for describing irreversible aggregation in the ballistic regime, including velocity distributions. The associated evolution for the macroscopic quantities is studied, and the general solution for Maxwell interaction models is obtained in the Fourier representation. (author). 23 refs

  10. Anisotropic shift of the irreversibility line by neutron irradiation

    International Nuclear Information System (INIS)

    Sauerzopf, F.M.; Wiesinger, H.P.; Weber, H.W.; Crabtree, G.W.; Frischherz, M.C.; Kirk, M.A.

    1991-09-01

    The irreversibility line of high-T c superconductors is shifted considerably by irradiating the material with fast neutrons. The anisotropic and non-monotonous shift is qualitatively explained by a simple model based on an interaction between three pinning mechanisms, the intrinsic pinning by the ab-planes, the weak pinning by the pre-irradiation defect structure, and strong pinning by neutron induced defect cascades. A correlation between the cascade density and the position of the irreversibility line is observed

  11. Measures of thermodynamic irreversibility in deterministic and stochastic dynamics

    International Nuclear Information System (INIS)

    Ford, Ian J

    2015-01-01

    It is generally observed that if a dynamical system is sufficiently complex, then as time progresses it will share out energy and other properties amongst its component parts to eliminate any initial imbalances, retaining only fluctuations. This is known as energy dissipation and it is closely associated with the concept of thermodynamic irreversibility, measured by the increase in entropy according to the second law. It is of interest to quantify such behaviour from a dynamical rather than a thermodynamic perspective and to this end stochastic entropy production and the time-integrated dissipation function have been introduced as analogous measures of irreversibility, principally for stochastic and deterministic dynamics, respectively. We seek to compare these measures. First we modify the dissipation function to allow it to measure irreversibility in situations where the initial probability density function (pdf) of the system is asymmetric as well as symmetric in velocity. We propose that it tests for failure of what we call the obversibility of the system, to be contrasted with reversibility, the failure of which is assessed by stochastic entropy production. We note that the essential difference between stochastic entropy production and the time-integrated modified dissipation function lies in the sequence of procedures undertaken in the associated tests of irreversibility. We argue that an assumed symmetry of the initial pdf with respect to velocity inversion (within a framework of deterministic dynamics) can be incompatible with the Past Hypothesis, according to which there should be a statistical distinction between the behaviour of certain properties of an isolated system as it evolves into the far future and the remote past. Imposing symmetry on a velocity distribution is acceptable for many applications of statistical physics, but can introduce difficulties when discussing irreversible behaviour. (paper)

  12. Study and characterization of the irreversible transformation of electrically stressed planar Ti/TiO{sub x}/Ti junctions

    Energy Technology Data Exchange (ETDEWEB)

    Guillaume, N.; Puyoo, E., E-mail: etienne.puyoo@insa-lyon.fr; Le Berre, M.; Albertini, D.; Baboux, N.; Chevalier, C.; Ayadi, K.; Grégoire, J.; Gautier, B.; Calmon, F. [Institut des Nanotechnologies de Lyon, Université de Lyon, INL UMR 5270, CNRS, INSA de Lyon, Villeurbanne F-69621 (France)

    2015-10-14

    We investigate the properties and characteristics of planar Ti/TiO{sub x}/Ti junctions, which consist of transverse TiO{sub x} lines drawn on Ti test patterns. Junctions are elaborated by means of local anodic oxidation using atomic force microscopy. An irreversible morphological transformation occurring in a reproducible manner is observed when these planar junctions are electrically stressed under ambient atmosphere. Structural and chemical analyses based on transmission electron microscopy techniques reveal the extension of the initial amorphous TiO{sub x} into a crystalline rutile phase. This irreversible transformation is proven to vanish completely if the electrical stress occurs under vacuum atmosphere. Finally, we carry out temperature dependent electrical measurements in order to elucidate their conduction mechanism: Schottky emission above an ultra-low potential barrier is assumed to dominate under vacuum atmosphere whereas ionic conduction seems to prevail in air.

  13. Fundamental economic irreversibilities influence policies for enhancing international forest phytosanitary security

    Science.gov (United States)

    Thomas P. Holmes; Will Allen; Robert G. Haight; E. Carina H. Keskitalo; Mariella Marzano; Maria Pettersson; Christopher P. Quine; E. R. Langer

    2017-01-01

    National and international efforts to manage forest biosecurity create tension between opposing sources of ecological and economic irreversibility. Phytosanitary policies designed to protect national borders from biological invasions incur sunk costs deriving from economic and political irreversibilities that incentivizes wait-and-see decision-making. However, the...

  14. The use of TiO2 nanoparticles to reduce refrigerator ir-reversibility

    International Nuclear Information System (INIS)

    Padmanabhan, Venkataramana Murthy V.; Palanisamy, Senthilkumar

    2012-01-01

    Highlights: ► COP of hydrocarbons mixture VCRSs increases less when compared to R134a. ► Compressor ir-reversibility of VCRSs decreases by 33% (R134a), 14% (R436A and R436B). ► Total ir-reversibility of selected VCRSs decreases. ► Exergy efficiency of R134a is exceptionally low at lower reference temperature. ► Exergy efficiency of selected VCRSs increases. - Abstract: The ir-reversibility at the process of a vapour-compression refrigeration system (VCRS) with nanoparticles in the working fluid was investigated experimentally. Mineral oil (MO) with 0.1 g L −1 TiO 2 nanoparticles mixture were used as the lubricant instead of Polyol-ester (POE) oil in the R134a, R436A (R290/R600a-56/44-wt.%) and R436B (R290/R600a-52/48-wt.%)VCRSs. The VCRS ir-reversibility at the process with the nanoparticles was investigated using second law of thermodynamics. The results indicate that R134a, R436A and R436B and MO with TiO 2 nanoparticles work normally and safely in the VCRS. The VCRSs total ir-reversibility (529, 588 and 570 W) at different process was better than the R134a, R436A and R436B and POE oil system (777, 697 and 683 W). The same tests with Al 2 O 3 nanoparticles showed that the different nanoparticles properties have little effect on the VCRS ir-reversibility. Thus, TiO 2 nanoparticles can be used in VCRS with reciprocating compressor to considerably reduce ir-reversibility at the process.

  15. Irreversible Local Markov Chains with Rapid Convergence towards Equilibrium

    Science.gov (United States)

    Kapfer, Sebastian C.; Krauth, Werner

    2017-12-01

    We study the continuous one-dimensional hard-sphere model and present irreversible local Markov chains that mix on faster time scales than the reversible heat bath or Metropolis algorithms. The mixing time scales appear to fall into two distinct universality classes, both faster than for reversible local Markov chains. The event-chain algorithm, the infinitesimal limit of one of these Markov chains, belongs to the class presenting the fastest decay. For the lattice-gas limit of the hard-sphere model, reversible local Markov chains correspond to the symmetric simple exclusion process (SEP) with periodic boundary conditions. The two universality classes for irreversible Markov chains are realized by the totally asymmetric SEP (TASEP), and by a faster variant (lifted TASEP) that we propose here. We discuss how our irreversible hard-sphere Markov chains generalize to arbitrary repulsive pair interactions and carry over to higher dimensions through the concept of lifted Markov chains and the recently introduced factorized Metropolis acceptance rule.

  16. A Fingerprint Encryption Scheme Based on Irreversible Function and Secure Authentication

    Directory of Open Access Journals (Sweden)

    Yijun Yang

    2015-01-01

    Full Text Available A fingerprint encryption scheme based on irreversible function has been designed in this paper. Since the fingerprint template includes almost the entire information of users’ fingerprints, the personal authentication can be determined only by the fingerprint features. This paper proposes an irreversible transforming function (using the improved SHA1 algorithm to transform the original minutiae which are extracted from the thinned fingerprint image. Then, Chinese remainder theorem is used to obtain the biokey from the integration of the transformed minutiae and the private key. The result shows that the scheme has better performance on security and efficiency comparing with other irreversible function schemes.

  17. A minimal dissipation type-based classification in irreversible thermodynamics and microeconomics

    Science.gov (United States)

    Tsirlin, A. M.; Kazakov, V.; Kolinko, N. A.

    2003-10-01

    We formulate the problem of finding classes of kinetic dependencies in irreversible thermodynamic and microeconomic systems for which minimal dissipation processes belong to the same type. We show that this problem is an inverse optimal control problem and solve it. The commonality of this problem in irreversible thermodynamics and microeconomics is emphasized.

  18. Optimization of the performance characteristics in an irreversible magnetic Brayton refrigeration cycle

    International Nuclear Information System (INIS)

    Wang Hao; Liu Sanqiu

    2008-01-01

    An irreversible cycle model of magnetic Brayton refrigerators is established, in which the thermal resistance and irreversibility in the two adiabatic processes are taken into account. Expressions for several important performance parameters, such as the coefficient of performance, cooling rate and power input are derived. Moreover, the optimal performance parameters are obtained at the maximum coefficient of performance. The optimization region (or criteria) for an irreversible magnetic Brayton refrigerator is obtained. The results obtained here have general significance and will be helpful to understand deeply the performance of a magnetic Brayton refrigeration cycle

  19. BNNT-mediated irreversible electroporatio: its potential on cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Vittoria Raffa, Cristina Riggio, Michael W. Smith, Kevin C. Jordan, Wei Cao, Alfred Cuschieri

    2012-10-01

    Tissue ablation, i.e., the destruction of undesirable tissues, has become an important minimally invasive technique alternative to resection surgery for the treatment of tumours. Several methods for tissue ablation are based on thermal techniques using cold, e.g. cryosurgery [1] or heat, e.g. radiofrequency [2] or high-intensity focused ultrasound [3] or nanoparticle-mediated irradiation [4]. Alternatively, irreversible electroporation (IRE) has been proposed as non thermal technique for minimally invasive tissue ablation based on the use of electrical pulses. When the electric field is applied to a cell, a change in transmembrane potential is induced, which can cause biochemical and physiological changes of the cell. When the threshold value of the transmembrane potential is exceeded, the cell membrane becomes permeable, thus allowing entrance of molecules that otherwise cannot cross the membrane [5]. A further increase in the electric field intensity may cause irreversible membrane permeabilization and cell death. These pulses create irreversible defects (pores) in the cell membrane lipid bilayer, causing cell death through loss of cell homeostasis [6]. This is desirable in tumour ablation in order to produce large cell death, without the use of cytostatic drugs. A study of Davalos, Mir and Rubinsky showed that IRE can ablate substantial volumes of tissue without inducing a thermal effect and therefore serve as an independent and new tissue ablation modality; this opened the way to the use of IRE in surgery [7]. Their finding was subsequently confirmed in studies on cells [8], small animal models [9] and in large animal models in the liver [10] and the heart [11]. The most important finding in these papers is that irreversible electroporation produces precisely delineated ablation zones with cell scale resolution between ablated and non-ablated areas, without zones in which the extent of damage changes gradually as during thermal ablation. Furthermore, it is

  20. Population dose-response analysis of daily seizure count following vigabatrin therapy in adult and pediatric patients with refractory complex partial seizures.

    Science.gov (United States)

    Nielsen, Jace C; Hutmacher, Matthew M; Wesche, David L; Tolbert, Dwain; Patel, Mahlaqa; Kowalski, Kenneth G

    2015-01-01

    Vigabatrin is an irreversible inhibitor of γ-aminobutyric acid transaminase (GABA-T) and is used as an adjunctive therapy for adult patients with refractory complex partial seizures (rCPS). The purpose of this investigation was to describe the relationship between vigabatrin dosage and daily seizure rate for adults and children with rCPS and identify relevant covariates that might impact seizure frequency. This population dose-response analysis used seizure-count data from three pediatric and two adult randomized controlled studies of rCPS patients. A negative binomial distribution model adequately described daily seizure data. Mean seizure rate decreased with time after first dose and was described using an asymptotic model. Vigabatrin drug effects were best characterized by a quadratic model using normalized dosage as the exposure metric. Normalized dosage was an estimated parameter that allowed for individualized changes in vigabatrin exposure based on body weight. Baseline seizure rate increased with decreasing age, but age had no impact on vigabatrin drug effects after dosage was normalized for body weight differences. Posterior predictive checks indicated the final model was capable of simulating data consistent with observed daily seizure counts. Total normalized vigabatrin dosages of 1, 3, and 6 g/day were predicted to reduce seizure rates 23.2%, 45.6%, and 48.5%, respectively. © 2014, The American College of Clinical Pharmacology.

  1. Fluctuation theorems in feedback-controlled open quantum systems: Quantum coherence and absolute irreversibility

    Science.gov (United States)

    Murashita, Yûto; Gong, Zongping; Ashida, Yuto; Ueda, Masahito

    2017-10-01

    The thermodynamics of quantum coherence has attracted growing attention recently, where the thermodynamic advantage of quantum superposition is characterized in terms of quantum thermodynamics. We investigate the thermodynamic effects of quantum coherent driving in the context of the fluctuation theorem. We adopt a quantum-trajectory approach to investigate open quantum systems under feedback control. In these systems, the measurement backaction in the forward process plays a key role, and therefore the corresponding time-reversed quantum measurement and postselection must be considered in the backward process, in sharp contrast to the classical case. The state reduction associated with quantum measurement, in general, creates a zero-probability region in the space of quantum trajectories of the forward process, which causes singularly strong irreversibility with divergent entropy production (i.e., absolute irreversibility) and hence makes the ordinary fluctuation theorem break down. In the classical case, the error-free measurement ordinarily leads to absolute irreversibility, because the measurement restricts classical paths to the region compatible with the measurement outcome. In contrast, in open quantum systems, absolute irreversibility is suppressed even in the presence of the projective measurement due to those quantum rare events that go through the classically forbidden region with the aid of quantum coherent driving. This suppression of absolute irreversibility exemplifies the thermodynamic advantage of quantum coherent driving. Absolute irreversibility is shown to emerge in the absence of coherent driving after the measurement, especially in systems under time-delayed feedback control. We show that absolute irreversibility is mitigated by increasing the duration of quantum coherent driving or decreasing the delay time of feedback control.

  2. Irreversible adsorption of phenolic compounds by activated carbons

    Energy Technology Data Exchange (ETDEWEB)

    Grant, T.M.; King, C.J.

    1988-12-01

    Studies were undertaken to determine the reasons why phenolic sorbates can be difficult to remove and recover from activated carbons. The chemical properties of the sorbate and the adsorbent surface, and the influences of changes in the adsorption and desorption conditions were investigated. Comparison of isotherms established after different contact times or at different temperatures indicated that phenolic compounds react on carbon surfaces. The reaction rate is a strong function of temperature. Regeneration of carbons by leaching with acetone recovered at least as much phenol as did regeneration with other solvents or with displacers. The physiochemical properties of adsorbents influences irreversible uptakes. Sorbates differed markedly in their tendencies to undergo irreversible adsorption. 64 refs., 47 figs., 32 tabs.

  3. Irreversible adsorption of phenolic compounds by activated carbons

    International Nuclear Information System (INIS)

    Grant, T.M.; King, C.J.

    1988-12-01

    Studies were undertaken to determine the reasons why phenolic sorbates can be difficult to remove and recover from activated carbons. The chemical properties of the sorbate and the adsorbent surface, and the influences of changes in the adsorption and desorption conditions were investigated. Comparison of isotherms established after different contact times or at different temperatures indicated that phenolic compounds react on carbon surfaces. The reaction rate is a strong function of temperature. Regeneration of carbons by leaching with acetone recovered at least as much phenol as did regeneration with other solvents or with displacers. The physiochemical properties of adsorbents influences irreversible uptakes. Sorbates differed markedly in their tendencies to undergo irreversible adsorption. 64 refs., 47 figs., 32 tabs

  4. Port contact systems for irreversible thermodynamical systems

    NARCIS (Netherlands)

    Eberard, D.; Maschke, B.M.; Schaft, A.J. van der

    2005-01-01

    In this paper we propose a definition of control contact systems, generalizing input-output Hamiltonian systems, to cope with models arising from irreversible Thermodynamics. We exhibit a particular subclass of these systems, called conservative, that leaves invariant some Legendre submanifold (the

  5. Classical many-body theory with retarded interactions: Dynamical irreversibility and determinism without probabilities

    Energy Technology Data Exchange (ETDEWEB)

    Zakharov, A.Yu., E-mail: Anatoly.Zakharov@novsu.ru; Zakharov, M.A., E-mail: ma_zakharov@list.ru

    2016-01-28

    The exact equations of motion for microscopic density of classical many-body system with account of inter-particle retarded interactions is derived. It is shown that interactions retardation leads to irreversible behavior of many-body systems. - Highlights: • A new form of equation of motion of classical many-body system is proposed. • Interactions retardation as one of the mechanisms of many-body system irreversibility. • Irreversibility and determinism without probabilities. • The possible way to microscopic foundation of thermodynamics.

  6. β-characterization by irreversibility analysis: A thermoeconomic diagnosis method

    International Nuclear Information System (INIS)

    Zaleta-Aguilar, Alejandro; Olivares-Arriaga, Abraham; Cano-Andrade, Sergio; Rodriguez-Alejandro, David A.

    2016-01-01

    This paper presents a reconciliation methodology for the diagnosis of energy systems. The methodology is based on the characterization of irreversibilities in the components of an energy system. These irreversibilities can be attributed to malfunctions or dysfunctions. The characterization of irreversibilities as presented here makes possible to reconcile the Actual Operating Condition (AOC) versus the Reference Operating Condition (ROC) of the energy system in a real-time manner. The diagnosis methodology introduces a parameter β, which represents the total exergy or useful work of a component in terms of its inlet and output streams at either design (full-load) or off-design (partial-load) conditions. The methodology is applied to the diagnosis of an actual Natural Gas Combined Cycle (NGCC) power plant. Data for the model is obtained directly from the plant by monitoring its performance at every time; thus, a real-time thermodynamic diagnosis for the system is obtained. Results show that the methodology presented here is able to detect and quantify the deviations on the performance of the NGCC power plant during its real-time operation. Based on the detection and quantification of these deviations, the user is able to make recommendations to schedule maintenance on the components where the irreversibilities are present. - Highlights: • A new methodology for thermoeconomic diagnosis of energy systems is presented. • A parameter β is defined for characterization of the components of an energy system. • The β characterization methodology is tested in a real 420 MW NGCC power plant. • Results show that the complexity of a diagnosis analysis is reduced substantially.

  7. Quantum thermodynamics: Microscopic foundations of entropy and of entropy generation by irreversibility

    Directory of Open Access Journals (Sweden)

    Beretta, Gian Paolo

    2008-02-01

    Full Text Available What is the physical significance of entropy? What is the physical origin of irreversibility? Do entropy and irreversibility exist only for complex and macroscopic systems? Most physicists still accept and teach that the rationalization of these fundamental questions is given by Statistical Mechanics. Indeed, for everyday laboratory physics, the mathematical formalism of Statistical Mechanics (canonical and grand-canonical, Boltzmann, Bose-Einstein and Fermi-Dirac distributions allows a successful description of the thermodynamic equilibrium properties of matter, including entropy values. However, as already recognized by Schrodinger in 1936, Statistical Mechanics is impaired by conceptual ambiguities and logical inconsistencies, both in its explanation of the meaning of entropy and in its implications on the concept of state of a system. An alternative theory has been developed by Gyftopoulos, Hatsopoulos and the present author to eliminate these stumbling conceptual blocks while maintaining the mathematical formalism so successful in applications. To resolve both the problem of the meaning of entropy and that of the origin of irreversibility we have built entropy and irreversibility into the laws of microscopic physics. The result is a theory, that we call Quantum Thermodynamics, that has all the necessary features to combine Mechanics and Thermodynamics uniting all the successful results of both theories, eliminating the logical inconsistencies of Statistical Mechanics and the paradoxes on irreversibility, and providing an entirely new perspective on the microscopic origin of irreversibility, nonlinearity (therefore including chaotic behavior and maximal-entropy-generation nonequilibrium dynamics. In this paper we discuss the background and formalism of Quantum Thermodynamics including its nonlinear equation of motion and the main general results. Our objective is to show in a not-too-technical manner that this theory provides indeed a

  8. A new approach to irreversibility in deep inelastic collisions

    International Nuclear Information System (INIS)

    Nemes, M.C.

    1982-01-01

    We use concepts of statistical mechanics to discuss the irreversible character of the experimental data in deep inelastic collisions. A definition of irreversibility proposed by Ruch permits a unified overview on current theories which describe these reactions. An information theoretical analysis of the data leads to a Fokker-Planck equation for the collective variables (excitation energy, charge and mass). The concept of mixing distance can serve as a quantitative measure to characterize the 'approach to equilibrium'. We apply it to the brownian motion as an illustration and also to the phenomenological analysis of deep inelastic scattering data with interesting results. (orig.)

  9. Extremum principles for irreversible processes

    International Nuclear Information System (INIS)

    Hillert, M.; Agren, J.

    2006-01-01

    Hamilton's extremum principle is a powerful mathematical tool in classical mechanics. Onsager's extremum principle may play a similar role in irreversible thermodynamics and may also become a valuable tool. His principle may formally be regarded as a principle of maximum rate of entropy production but does not have a clear physical interpretation. Prigogine's principle of minimum rate of entropy production has a physical interpretation when it applies, but is not strictly valid except for a very special case

  10. Operation voltage of the counting system of nuclear traces in solids

    International Nuclear Information System (INIS)

    Garcia, M.L.; Quirino, L.L.; Mireles, F.; Davila, J.I.; Pinedo, J.L.; Lugo, J.F.; Vadillo, V.E.

    2002-01-01

    The semi-automatic counting system based on electric spark and used for traces reading in solid state detectors is evaluated for obtaining its counting voltage and also the breaking voltage of material. In the treatment of the solid state detectors it is continued the NTD methodology for concluding with the individual counting of the films, whose graphics offer the existing relationship among the applied voltage and the traces number. From each film a counting and breaking voltages are obtained. Finally, an average voltage of all them is estimated. (Author)

  11. Irreversible performance of a quantum harmonic heat engine

    Science.gov (United States)

    Rezek, Yair; Kosloff, Ronnie

    2006-05-01

    The unavoidable irreversible loss of power in a heat engine is found to be of quantum origin. Following thermodynamic tradition, a model quantum heat engine operating in an Otto cycle is analysed, where the working medium is composed of an ensemble of harmonic oscillators and changes in volume correspond to changes in the curvature of the potential well. Equations of motion for quantum observables are derived for the complete cycle of operation. These observables are sufficient to determine the state of the system and with it all thermodynamical variables. Once the external controls are set, the engine settles to a limit cycle. Conditions for optimal work, power and entropy production are derived. At high temperatures and quasistatic operating conditions, the efficiency at maximum power coincides with the endoreversible result \\eta_q=1-\\sqrt{{T_c}/{T_h}} . The optimal compression ratio varies from {\\cal C} =\\sqrt{T_h/T_c} in the quasistatic limit where the irreversibility is dominated by heat conductance to {\\cal C} =(T_h/T_c)^{1/4} in the sudden limit when the irreversibility is dominated by friction. When the engine deviates from adiabatic conditions, the performance is subject to friction. The origin of this friction can be traced to the noncommutability of the kinetic and potential energy of the working medium.

  12. Anaesthetic efficacy of lidocaine/clonidine for inferior alveolar nerve block in patients with irreversible pulpitis.

    Science.gov (United States)

    Shadmehr, E; Aminozarbian, M G; Akhavan, A; Mahdavian, P; Davoudi, A

    2017-06-01

    This prospective, randomized, double-blind study aimed to compare the efficacy of lidocaine with epinephrine versus lidocaine with clonidine for inferior alveolar nerve block (IANB) and hemodynamic stability (heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure) in patients with irreversible pulpitis. One hundred patients with irreversible pulpitis in mandibular molar teeth randomly received 1.8 mL of 2% lidocaine with clonidine (15 μg mL -1 ) or 1.8 mL of 2% lidocaine with epinephrine (12.5 μg mL -1 ), using a conventional IANB technique. Endodontic access cavities were prepared 15 min after solution deposition, and all patients were required to have profound lip numbness. Success was defined as no or mild pain (visual analog scale recording) upon endodontic access cavity preparation or initial canal instrumentation. The hemodynamic parameters were measured before, during and 5, 10 and 30 min after administration. Finally, the collected data were subjected to independent t-test, chi-square and Fisher's exact test using spss software ver.20 at a significant level of 0.05. The success rates for IANB using lidocaine with epinephrine and lidocaine with clonidine solutions were 29% and 59%, respectively. The clonidine group exhibited a significantly higher success rate (P < 0.05). Five minutes after drug administration, systolic blood pressure and heart rate significantly increased in the lidocaine with epinephrine group and insignificantly decreased in lidocaine with clonidine group. For mandibular molars with irreversible pulpitis, addition of clonidine to lidocaine improved the success rate of IANB compared to a standard lidocaine/epinephrine solution. © 2016 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  13. Risk Aversion, Price Uncertainty and Irreversible Investments

    NARCIS (Netherlands)

    van den Goorbergh, R.W.J.; Huisman, K.J.M.; Kort, P.M.

    2003-01-01

    This paper generalizes the theory of irreversible investment under uncertainty by allowing for risk averse investors in the absence of com-plete markets.Until now this theory has only been developed in the cases of risk neutrality, or risk aversion in combination with complete markets.Within a

  14. Canonical formalism, fundamental equation, and generalized thermomechanics for irreversible fluids with heat transfer

    International Nuclear Information System (INIS)

    Sieniutycz, S.; Berry, R.S.

    1993-01-01

    A Lagrangian with dissipative (e.g., Onsager's) potentials is constructed for the field description of irreversible heat-conducting fluids, off local equilibrium. Extremum conditions of action yield Clebsch representations of temperature, chemical potential, velocities, and generalized momenta, including a thermal momentum introduced recently [R. L. Selinger and F. R. S. Whitham, Proc. R. Soc. London, Ser. A 302, 1 (1968); S. Sieniutycz and R. S. Berry, Phys. Rev. A 40, 348 (1989)]. The basic question asked is ''To what extent may irreversibility, represented by a given form of the entropy source, influence the analytical form of the conservation laws for the energy and momentum?'' Noether's energy for a fluid with heat flow is obtained, which leads to a fundamental equation and extended Hamiltonian dynamics obeying the second law of thermodynamics. While in the case of the Onsager potentials this energy coincides numerically with the classical energy E, it contains an extra term (vanishing along the path) still contributing to an irreversible evolution. Components of the energy-momentum tensor preserve all terms regarded standardly as ''irreversible'' (heat, tangential stresses, etc.) generalized to the case when thermodynamics includes the state gradients and the so-called thermal phase, which we introduce here. This variable, the Lagrange multiplier of the entropy generation balance, is crucial for consistent treatment of irreversible processes via an action formalism. We conclude with the hypothesis that embedding the first and second laws in the context of the extremal behavior of action under irreversible conditions may imply accretion of an additional term to the classical energy

  15. Health Technology Assessment of CEM Pulpotomy in Permanent Molars with Irreversible Pulpitis

    Science.gov (United States)

    Yazdani, Shahram; Jadidfard, Mohammad-Pooyan; Tahani, Bahareh; Kazemian, Ali; Dianat, Omid; Alim Marvasti, Laleh

    2014-01-01

    Introduction: Teeth with irreversible pulpitis usually undergo root canal therapy (RCT). This treatment modality is often considered disadvantageous as it removes vital pulp tissue and weakens the tooth structure. A relatively new concept has risen which suggests vital pulp therapy (VPT) for irreversible pulpitis. VPT with calcium enriched mixture (VPT/CEM) has demonstrated favorable treatment outcomes when treating permanent molars with irreversible pulpitis. This study aims to compare patient related factors, safety and organizational consideration as parts of health technology assessment (HTA) of the new VPT/CEM biotechnology when compared with RCT. Materials and Methods: Patient related factors were assessed by looking at short- and long-term clinical success; safety related factors were evaluated by a specialist committee and discussion board involved in formulating healthcare policies. Organizational evaluation was performed and the social implications were assessed by estimating the costs, availability, accessibility and acceptability. The impact of VPT/CEM biotechnology was assessed by investigating the incidence of irreversible pulpitis and the effect of this treatment on reducing the burden of disease. Results: VPT/CEM biotechnology was deemed feasible and acceptable like RCT; however, it was more successful, accessible, affordable, available and also safer than RCT. Conclusion: When considering socioeconomic implications on oral health status and oral health-related quality of life of VPT/CEM, the novel biotechnology can be more effective and more efficient than RCT in mature permanent molars with irreversible pulpitis. PMID:24396372

  16. Onsager's reciprocity theorem in extended irreversible thermodynamics

    International Nuclear Information System (INIS)

    Garcia-Colin, L.S.; Velasco, R.M.

    1992-01-01

    In this paper we shall discuss the Onsager relations for the transport coefficients in a dilute monatomic gas described by the extended irreversible thermodynamics. Our discussion is based on a 26 variables description of the system and its corresponding comparison with the kinetic reciprocity between coefficients is shown (Author)

  17. Lie-admissible invariant treatment of irreversibility for matter and antimatter at the classical and operator levels

    International Nuclear Information System (INIS)

    Santilli, R.M.

    2006-01-01

    It was generally believed throughout the 20th century that irreversibility is a purely classical event without operator counterpart. however, a classical irreversible system cannot be consistently decomposed into a finite number of reversible quantum particles (and. vive versa), thus establishing that the origin of irreversibility is basically unknown at the dawn of the 21-st century. To resolve this problem. we adopt the historical analytical representation of irreversibility by Lagrange and Hamilton, that with external terms in their analytic equations; we show that, when properly written, the brackets of the time evolution characterize covering Lie-admissible algebras; we prove that the formalism has fully consistent operator counterpart given by the Lie-admissible branch of hadronic mechanics; we identify mathematical and physical inconsistencies when irreversible formulations are treated with the conventional mathematics used for reversible systems; we show that when the dynamical equations are treated with a novel irreversible mathematics, Lie-admissible formulations are fully consistent because invariant at both the classical and operator levels; and we complete our analysis with a number of explicit applications to irreversible processes in classical mechanics, particle physics and thermodynamics. The case of closed-isolated systems verifying conventional total conservation laws, yet possessing an irreversible structure, is treated via the simpler Lie-isotopic branch of hadronic mechanics. The analysis is conducted for both matter and antimatter at the classical and operator levels to prevent insidious inconsistencies occurring for the sole study of matter or, separately, antimatter

  18. Determination of phosphorus-32 in wet-digested plant leaves by Cerenkov counting

    International Nuclear Information System (INIS)

    Wahid, P.A.; Kamalam, N.V.; Sankar, S.J.

    1985-01-01

    A method of determination of 32 P activity in leaf samples by Cerenkov counting technique is described. The method involves wet digestion of oven-dried leaves with 1:1 nitric-perchloric acid mixture followed by transferring the digest into a scintillation counting vial with distilled water upto a final volume of 20 mL, and determining the activity in a liquid scintillation system. Reproducible count rates can be obtained if the vials are counted after 4h allowing the silica in the digest to settle. (author)

  19. Spectral deformation techniques applied to the study of quantum statistical irreversible processes

    International Nuclear Information System (INIS)

    Courbage, M.

    1978-01-01

    A procedure of analytic continuation of the resolvent of Liouville operators for quantum statistical systems is discussed. When applied to the theory of irreversible processes of the Brussels School, this method supports the idea that the restriction to a class of initial conditions is necessary to obtain an irreversible behaviour. The general results are tested on the Friedrichs model. (Auth.)

  20. Articaine for supplemental intraosseous anesthesia in patients with irreversible pulpitis.

    Science.gov (United States)

    Bigby, Jason; Reader, Al; Nusstein, John; Beck, Mike; Weaver, Joel

    2006-11-01

    The purpose of this study was to determine the anesthetic efficacy and heart rate effect of 4% articaine with 1:100,000 epinephrine for supplemental intraosseous injection in mandibular posterior teeth diagnosed with irreversible pulpitis. Thirty-seven emergency patients, diagnosed with irreversible pulpitis of a mandibular posterior tooth, received an inferior alveolar nerve block and had moderate-to-severe pain upon endodontic access. The Stabident system was used to administer 1.8 ml of 4% articaine with 1:100,000 epinephrine. Success of the intraosseous injection was defined as none or mild pain upon endodontic access or initial instrumentation. The results demonstrated that anesthetic success was obtained in 86% (32 of 37) of the patients. Maximum mean heart rate was increased 32 beats/minute during the intraosseous injection. We can conclude that when the inferior alveolar nerve block fails to provide profound pulpal anesthesia, the intraosseous injection of 4% articaine with 1:100,000 epinephrine would be successful 86% of the time in achieving pulpal anesthesia in mandibular posterior teeth of patients presenting with irreversible pulpitis.

  1. FINITE TIME THERMODYNAMIC MODELING AND ANALYSIS FOR AN IRREVERSIBLE ATKINSON CYCLE

    Directory of Open Access Journals (Sweden)

    Yanlin Ge

    2010-01-01

    Full Text Available Performance of an air-standard Atkinson cycle is analyzed by using finite-time thermodynamics. The irreversible cycle model which is more close to practice is founded. In this model, the non-linear relation between the specific heats of working fluid and its temperature, the friction loss computed according to the mean velocity of the piston, the internal irreversibility described by using the compression and expansion efficiencies, and heat transfer loss are considered. The relations between the power output and the compression ratio, between the thermal efficiency and the compression ratio, as well as the optimal relation between power output and the efficiency of the cycle are derived by detailed numerical examples. Moreover, the effects of internal irreversibility, heat transfer loss and friction loss on the cycle performance are analyzed. The results obtained in this paper may provide guidelines for the design of practical internal combustion engines.

  2. How to account for irreversibility in integrated assessment of climate change?; Comment tenir compte de l'irreversibilite dans l'evaluation integree du changement climatique?

    Energy Technology Data Exchange (ETDEWEB)

    Ha Duong, M

    1998-04-15

    How to account for irreversibility in integrated assessment of climate change? This Ph. D. thesis in Economics balances discounting, technical progress and the inertia of existing capital stock against uncertainty and the inertia of socio-economic systems to examine the issue of near term limitations of greenhouse gases emissions. After a general overview in chapter 2, and a more historical presentation of the debates in chapter 3, chapter 4 proceeds to review a large number of integrated assessment models. Chapter 5 introduces a Model on the Dynamics of Inertia and Adaptability of energy systems: DIAM, used to discuss how much previous studies might have overestimated the long term costs of CO{sub 2} limitations and underestimated adjustment costs. It shows that, given a target date for atmospheric CO{sub 2} concentration stabilisation, a higher inertia implies a lower optimal concentration trajectory. In a sequential decision framework, chapter 6 shows that current uncertainties about which CO{sub 2} concentration ceiling would not present dangerous interference with the climate system justifies precautionary action. Finally, chapter 7 uses the irreversibility effect theory to define formally situations of decision under controversy and compare the irreversibility of CO{sub 2} accumulation with the irreversibility of investments needed to moderate it. An option value for greenhouse gases emissions limitations is computed. (author)

  3. Ecological optimization and performance study of irreversible Stirling and Ericsson heat engines

    International Nuclear Information System (INIS)

    Tyagi, S K; Kaushik, S C; Salhotra, R

    2002-01-01

    The concept of finite time thermodynamics is used to determine the ecological function of irreversible Stirling and Ericsson heat engine cycles. The ecological function is defined as the power output minus power loss (irreversibility), which is the ambient temperature times, the entropy generation rate. The ecological function is maximized with respect to cycle temperature ratio and the expressions for the corresponding power output and thermal efficiency are derived at the optimal operating conditions. The effect of different operating parameters, the effectiveness on the hot, cold and the regenerative side heat exchangers, the cycle temperature ratio, heat capacitance ratio and the internal irreversibility parameter on the maximum ecological function are studied. It is found that the effect of regenerator effectiveness is more than the hot and cold side heat exchangers and the effect of the effectiveness on cold side heat exchanger is more than the effectiveness on the hot side heat exchanger on the maximum ecological function. It is also found that the effect of internal irreversibility parameter is more than the other parameters not only on the maximum ecological function but also on the corresponding power output and the thermal efficiency

  4. Performance characteristics and parametric optimization of an irreversible magnetic Ericsson heat-pump

    International Nuclear Information System (INIS)

    Wei Fang; Lin Guoxing; Chen Jincan; Brueck, Ekkes

    2011-01-01

    Taking into account the finite-rate heat transfer in the heat-transfer processes, heat leak between the two external heat reservoirs, regenerative loss, regeneration time, and internal irreversibility due to dissipation of the cycle working substance, an irreversible magnetic Ericsson heat-pump cycle is presented. On the basis of the thermodynamic properties of magnetic materials, the performance characteristics of the irreversible magnetic Ericsson heat-pump are investigated and the relationship between the optimal heating load and the coefficient of performance (COP) is derived. Moreover, the maximum heating load and the corresponding COP as well as the maximum COP and the corresponding heating load are obtained. Furthermore, the other optimal performance characteristics are discussed in detail. The results obtained here may provide some new information for the optimal parameter design and the development of real magnetic Ericsson heat-pumps. -- Research Highlights: →The effects of multi-irreversibilities on the performance of a magnetic heat-pump are revealed. →Mathematical expressions of the heating load and the COP are derived and the optimal performance and operating parameters are analyzed and discussed. →Several important performance bounds are determined.

  5. Ecological optimization and performance study of irreversible Stirling and Ericsson heat engines

    Science.gov (United States)

    Tyagi, S. K.; Kaushik, S. C.; Salhotra, R.

    2002-10-01

    The concept of finite time thermodynamics is used to determine the ecological function of irreversible Stirling and Ericsson heat engine cycles. The ecological function is defined as the power output minus power loss (irreversibility), which is the ambient temperature times, the entropy generation rate. The ecological function is maximized with respect to cycle temperature ratio and the expressions for the corresponding power output and thermal efficiency are derived at the optimal operating conditions. The effect of different operating parameters, the effectiveness on the hot, cold and the regenerative side heat exchangers, the cycle temperature ratio, heat capacitance ratio and the internal irreversibility parameter on the maximum ecological function are studied. It is found that the effect of regenerator effectiveness is more than the hot and cold side heat exchangers and the effect of the effectiveness on cold side heat exchanger is more than the effectiveness on the hot side heat exchanger on the maximum ecological function. It is also found that the effect of internal irreversibility parameter is more than the other parameters not only on the maximum ecological function but also on the corresponding power output and the thermal efficiency.

  6. Ecological optimization of an irreversible quantum Carnot heat engine with spin-1/2 systems

    International Nuclear Information System (INIS)

    Liu Xiaowei; Chen Lingen; Wu Feng; Sun Fengrui

    2010-01-01

    A model of a quantum heat engine with heat resistance, internal irreversibility and heat leakage and many non-interacting spin-1/2 systems is established in this paper. The quantum heat engine cycle is composed of two isothermal processes and two irreversible adiabatic processes and is referred to as a spin quantum Carnot heat engine. Based on the quantum master equation and the semi-group approach, equations of some important performance parameters, such as power output, efficiency, entropy generation rate and ecological function (a criterion representing the optimal compromise between exergy output rate and exergy loss rate), for the irreversible spin quantum Carnot heat engine are derived. The optimal ecological performance of the heat engine in the classical limit is analyzed with numerical examples. The effects of internal irreversibility and heat leakage on ecological performance are discussed in detail.

  7. Profit rate performance optimization for a generalized irreversible ...

    Indian Academy of Sciences (India)

    fer law system generalized irreversible combined refrigeration cycle model with finite-rate heat ...... Chen L, Sun F, Wu C 2004b Optimum allocation of heat exchanger area for refrigeration and air conditioning plants. Appl. Energy 77(3): 339– ...

  8. The Copenhagen primary care differential count (CopDiff) database

    DEFF Research Database (Denmark)

    Andersen, Christen Bertel L; Siersma, V.; Karlslund, W.

    2014-01-01

    BACKGROUND: The differential blood cell count provides valuable information about a person's state of health. Together with a variety of biochemical variables, these analyses describe important physiological and pathophysiological relations. There is a need for research databases to explore assoc...... the construction of the Copenhagen Primary Care Differential Count database as well as the distribution of characteristics of the population it covers and the variables that are recorded. Finally, it gives examples of its use as an inspiration to peers for collaboration.......BACKGROUND: The differential blood cell count provides valuable information about a person's state of health. Together with a variety of biochemical variables, these analyses describe important physiological and pathophysiological relations. There is a need for research databases to explore...... Practitioners' Laboratory has registered all analytical results since July 1, 2000. The Copenhagen Primary Care Differential Count database contains all differential blood cell count results (n=1,308,022) from July 1, 2000 to January 25, 2010 requested by general practitioners, along with results from analysis...

  9. Irreversible electroporation: state of the art

    Directory of Open Access Journals (Sweden)

    Wagstaff PGK

    2016-04-01

    Full Text Available Peter GK Wagstaff,1 Mara Buijs,1 Willemien van den Bos,1 Daniel M de Bruin,2 Patricia J Zondervan,1 Jean JMCH de la Rosette,1 M Pilar Laguna Pes1 1Department of Urology, 2Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, the Netherlands Abstract: The field of focal ablative therapy for the treatment of cancer is characterized by abundance of thermal ablative techniques that provide a minimally invasive treatment option in selected tumors. However, the unselective destruction inflicted by thermal ablation modalities can result in damage to vital structures in the vicinity of the tumor. Furthermore, the efficacy of thermal ablation intensity can be impaired due to thermal sink caused by large blood vessels in the proximity of the tumor. Irreversible electroporation (IRE is a novel ablation modality based on the principle of electroporation or electropermeabilization, in which electric pulses are used to create nanoscale defects in the cell membrane. In theory, IRE has the potential of overcoming the aforementioned limitations of thermal ablation techniques. This review provides a description of the principle of IRE, combined with an overview of in vivo research performed to date in the liver, pancreas, kidney, and prostate. Keywords: irreversible electroporation, IRE, tumor, ablation, focal therapy, cancer

  10. The degree of irreversibility in deterministic finite automata

    DEFF Research Database (Denmark)

    Axelsen, Holger Bock; Holzer, Markus; Kutrib, Martin

    2016-01-01

    the language, and show that the degree induces a strict infinite hierarchy of languages. We examine how the degree of irreversibility behaves under the usual language operations union, intersection, complement, concatenation, and Kleene star, showing tight bounds (some asymptotically) on the degree....

  11. Exergetic efficiency optimization for an irreversible heat pump ...

    Indian Academy of Sciences (India)

    This paper deals with the performance analysis and optimization for irreversible heat pumps working on reversed Brayton cycle with constant-temperature heat reservoirs by taking exergetic efficiency as the optimization objective combining exergy concept with finite-time thermodynamics (FTT). Exergetic efficiency is ...

  12. Peptide Drug Release Behavior from Biodegradable Temperature-Responsive Injectable Hydrogels Exhibiting Irreversible Gelation

    Directory of Open Access Journals (Sweden)

    Kazuyuki Takata

    2017-10-01

    Full Text Available We investigated the release behavior of glucagon-like peptide-1 (GLP-1 from a biodegradable injectable polymer (IP hydrogel. This hydrogel shows temperature-responsive irreversible gelation due to the covalent bond formation through a thiol-ene reaction. In vitro sustained release of GLP-1 from an irreversible IP formulation (F(P1/D+PA40 was observed compared with a reversible (physical gelation IP formulation (F(P1. Moreover, pharmaceutically active levels of GLP-1 were maintained in blood after subcutaneous injection of the irreversible IP formulation into rats. This system should be useful for the minimally invasive sustained drug release of peptide drugs and other water-soluble bioactive reagents.

  13. Irreversible denaturation of maltodextrin glucosidase studied by differential scanning calorimetry, circular dichroism, and turbidity measurements.

    Science.gov (United States)

    Goyal, Megha; Chaudhuri, Tapan K; Kuwajima, Kunihiro

    2014-01-01

    Thermal denaturation of Escherichia coli maltodextrin glucosidase was studied by differential scanning calorimetry, circular dichroism (230 nm), and UV-absorption measurements (340 nm), which were respectively used to monitor heat absorption, conformational unfolding, and the production of solution turbidity. The denaturation was irreversible, and the thermal transition recorded at scan rates of 0.5-1.5 K/min was significantly scan-rate dependent, indicating that the thermal denaturation was kinetically controlled. The absence of a protein-concentration effect on the thermal transition indicated that the denaturation was rate-limited by a mono-molecular process. From the analysis of the calorimetric thermograms, a one-step irreversible model well represented the thermal denaturation of the protein. The calorimetrically observed thermal transitions showed excellent coincidence with the turbidity transitions monitored by UV-absorption as well as with the unfolding transitions monitored by circular dichroism. The thermal denaturation of the protein was thus rate-limited by conformational unfolding, which was followed by a rapid irreversible formation of aggregates that produced the solution turbidity. It is thus important to note that the absence of the protein-concentration effect on the irreversible thermal denaturation does not necessarily means the absence of protein aggregation itself. The turbidity measurements together with differential scanning calorimetry in the irreversible thermal denaturation of the protein provided a very effective approach for understanding the mechanisms of the irreversible denaturation. The Arrhenius-equation parameters obtained from analysis of the thermal denaturation were compared with those of other proteins that have been reported to show the one-step irreversible thermal denaturation. Maltodextrin glucosidase had sufficiently high kinetic stability with a half-life of 68 days at a physiological temperature (37°C).

  14. Anesthetic Efficacy in Irreversible Pulpitis: A Randomized Clinical Trial.

    Science.gov (United States)

    Allegretti, Carlos E; Sampaio, Roberta M; Horliana, Anna C R T; Armonia, Paschoal L; Rocha, Rodney G; Tortamano, Isabel Peixoto

    2016-01-01

    Inferior alveolar nerve block has a high failure rate in the treatment of mandibular posterior teeth with irreversible pulpitis. The aim of this study was to compare the anesthetic efficacy of 4% articaine, 2% lidocaine and 2% mepivacaine, all in combination with 1:100,000 epinephrine, in patients with irreversible pulpitis of permanent mandibular molars during a pulpectomy procedure. Sixty-six volunteers from the Emergency Center of the School of Dentistry, University of São Paulo, randomly received 3.6 mL of local anesthetic as a conventional inferior alveolar nerve block (IANB). The subjective signal of lip numbness, pulpal anesthesia and absence of pain during the pulpectomy procedure were evaluated respectively, by questioning the patient, stimulation using an electric pulp tester and a verbal analogue scale. All patients reported the subjective signal of lip numbness. Regarding pulpal anesthesia success as measured with the pulp tester, the success rate was respectively 68.2% for mepivacaine, 63.6% for articaine and 63.6% for lidocaine. Regarding patients who reported no pain or mild pain during the pulpectomy, the success rate was, respectively 72.7% for mepivacaine, 63.6% for articaine and 54.5% for lidocaine. These differences were not statistically significant. Neither of the solutions resulted in 100% anesthetic success in patients with irreversible pulpitis of mandibular molars.

  15. Protecting count queries in study design.

    Science.gov (United States)

    Vinterbo, Staal A; Sarwate, Anand D; Boxwala, Aziz A

    2012-01-01

    Today's clinical research institutions provide tools for researchers to query their data warehouses for counts of patients. To protect patient privacy, counts are perturbed before reporting; this compromises their utility for increased privacy. The goal of this study is to extend current query answer systems to guarantee a quantifiable level of privacy and allow users to tailor perturbations to maximize the usefulness according to their needs. A perturbation mechanism was designed in which users are given options with respect to scale and direction of the perturbation. The mechanism translates the true count, user preferences, and a privacy level within administrator-specified bounds into a probability distribution from which the perturbed count is drawn. Users can significantly impact the scale and direction of the count perturbation and can receive more accurate final cohort estimates. Strong and semantically meaningful differential privacy is guaranteed, providing for a unified privacy accounting system that can support role-based trust levels. This study provides an open source web-enabled tool to investigate visually and numerically the interaction between system parameters, including required privacy level and user preference settings. Quantifying privacy allows system administrators to provide users with a privacy budget and to monitor its expenditure, enabling users to control the inevitable loss of utility. While current measures of privacy are conservative, this system can take advantage of future advances in privacy measurement. The system provides new ways of trading off privacy and utility that are not provided in current study design systems.

  16. Sample size effect on the determination of the irreversibility line of high-Tc superconductors

    International Nuclear Information System (INIS)

    Li, Q.; Suenaga, M.; Li, Q.; Freltoft, T.

    1994-01-01

    The irreversibility lines of a high-J c superconducting Bi 2 Sr 2 Ca 2 Cu 3 O x /Ag tape were systematically measured upon a sequence of subdivisions of the sample. The irreversibility field H r (T) (parallel to the c axis) was found to change approximately as L 0.13 , where L is the effective dimension of the superconducting tape. Furthermore, it was found that the irreversibility line for a grain-aligned Bi 2 Sr 2 Ca 2 Cu 3 O x specimen can be approximately reproduced by the extrapolation of this relation down to a grain size of a few tens of micrometers. The observed size effect could significantly obscure the real physical meaning of the irreversibility lines. In addition, this finding surprisingly indicated that the Bi 2 Sr 2 Ca 2 Cu 2 O x /Ag tape and grain-aligned specimen may have similar flux line pinning strength

  17. Irreversible absorption heat-pump and its optimal performance

    International Nuclear Information System (INIS)

    Chen Lingen; Qin Xiaoyong; Sun Fengrui; Wu Chih

    2005-01-01

    On the basis of an endoreversible absorption heat-pump cycle, a generalized irreversible four-heat-reservoir absorption heat-pump cycle model is established by taking account of the heat resistances, heat leak and irreversibilities due to the internal dissipation of the working substance. The heat transfer between the heat reservoir and the working substance is assumed to obey the linear (Newtonian) heat-transfer law, and the overall heat-transfer surface area of the four heat-exchangers is assumed to be constant. The fundamental optimal relations between the coefficient of performance (COP) and the heating-load, the maximum COP and the corresponding heating-load, the maximum heating load and the corresponding COP, as well as the optimal temperatures of the working substance and the optimal heat-transfer surface areas of the four heat-exchangers are derived by using finite-time thermodynamics. Moreover, the effects of the cycle parameters on the characteristics of the cycle are studied by numerical examples

  18. Quantum mechanical irreversibility and measurement

    CERN Document Server

    Grigolini, P

    1993-01-01

    This book is intended as a tutorial approach to some of the techniques used to deal with quantum dissipation and irreversibility, with special focus on their applications to the theory of measurements. The main purpose is to provide readers without a deep expertise in quantum statistical mechanics with the basic tools to develop a critical judgement on whether the major achievements in this field have to be considered a satisfactory solution of quantum paradox, or rather this ambitious achievement has to be postponed to when a new physics, more general than quantum and classical physics, will

  19. Reversing the irreversible: From limit cycles to emergent time symmetry

    Science.gov (United States)

    Cortês, Marina; Smolin, Lee

    2018-01-01

    In 1979 Penrose hypothesized that the arrows of time are explained by the hypothesis that the fundamental laws are time irreversible [R. Penrose, in General Relativity: An Einstein Centenary Survey (1979)]. That is, our reversible laws, such as the standard model and general relativity are effective, and emerge from an underlying fundamental theory which is time irreversible. In [M. Cortês and L. Smolin, Phys. Rev. D 90, 084007 (2014), 10.1103/PhysRevD.90.084007; 90, 044035 (2014), 10.1103/PhysRevD.90.044035; 93, 084039 (2016), 10.1103/PhysRevD.93.084039] we put forward a research program aiming at realizing just this. The aim is to find a fundamental description of physics above the Planck scale, based on irreversible laws, from which will emerge the apparently reversible dynamics we observe on intermediate scales. Here we continue that program and note that a class of discrete dynamical systems are known to exhibit this very property: they have an underlying discrete irreversible evolution, but in the long term exhibit the properties of a time reversible system, in the form of limit cycles. We connect this to our original model proposal in [M. Cortês and L. Smolin, Phys. Rev. D 90, 084007 (2014), 10.1103/PhysRevD.90.084007], and show that the behaviors obtained there can be explained in terms of the same phenomenon: the attraction of the system to a basin of limit cycles, where the dynamics appears to be time reversible. Further than that, we show that our original models exhibit the very same feature: the emergence of quasiparticle excitations obtained in the earlier work in the space-time description is an expression of the system's convergence to limit cycles when seen in the causal set description.

  20. Nonequilibrium and irreversibility

    CERN Document Server

    Gallavotti, Giovanni

    2014-01-01

    This book concentrates on the properties of the stationary states in chaotic systems of particles or fluids, leaving aside the theory of the way they can be reached. The stationary states of particles or of fluids (understood as probability distributions on microscopic configurations or on the fields describing continua) have received important new ideas and data from numerical simulations and reviews are needed. The starting point is to find out which time invariant distributions come into play in physics. A special feature of this book is the historical approach. To identify the problems the author analyzes the papers of the founding fathers Boltzmann, Clausius and Maxwell including translations of the relevant (parts of ) historical documents. He also establishes a close link between treatment of irreversible phenomena in statistical mechanics and the theory of chaotic systems at and beyond the onset of turbulence as developed by Sinai, Ruelle, Bowen (SRB) and others: the author gives arguments intending t...

  1. How to account for irreversibility in integrated assessment of climate change?; Comment tenir compte de l'irreversibilite dans l'evaluation integree du changement climatique?

    Energy Technology Data Exchange (ETDEWEB)

    Ha Duong, M

    1998-04-15

    How to account for irreversibility in integrated assessment of climate change? This Ph. D. thesis in Economics balances discounting, technical progress and the inertia of existing capital stock against uncertainty and the inertia of socio-economic systems to examine the issue of near term limitations of greenhouse gases emissions. After a general overview in chapter 2, and a more historical presentation of the debates in chapter 3, chapter 4 proceeds to review a large number of integrated assessment models. Chapter 5 introduces a Model on the Dynamics of Inertia and Adaptability of energy systems: DIAM, used to discuss how much previous studies might have overestimated the long term costs of CO{sub 2} limitations and underestimated adjustment costs. It shows that, given a target date for atmospheric CO{sub 2} concentration stabilisation, a higher inertia implies a lower optimal concentration trajectory. In a sequential decision framework, chapter 6 shows that current uncertainties about which CO{sub 2} concentration ceiling would not present dangerous interference with the climate system justifies precautionary action. Finally, chapter 7 uses the irreversibility effect theory to define formally situations of decision under controversy and compare the irreversibility of CO{sub 2} accumulation with the irreversibility of investments needed to moderate it. An option value for greenhouse gases emissions limitations is computed. (author)

  2. Investment Irreversibility and Precautionary Savings in General Equilibrium

    DEFF Research Database (Denmark)

    Ejarque, João

    than irreversibility effects. If shocks are idiosyncratic and affect a cross section of agents over capital, an increase in their variance may induce an increase in aggregate investment even if all agents have an incentive to invest less, because zero investment is now an active lower bound for part...

  3. Determining Gate Count Reliability in a Library Setting

    Directory of Open Access Journals (Sweden)

    Jeffrey Phillips

    2016-09-01

    Full Text Available Objective – Patron counts are a common form of measurement for library assessment. To develop accurate library statistics, it is necessary to determine any differences between various counting devices. A yearlong comparison between card reader turnstiles and laser gate counters in a university library sought to offer a standard percentage of variance and provide suggestions to increase the precision of counts. Methods – The collection of library exit counts identified the differences between turnstile and laser gate counter data. Statistical software helped to eliminate any inaccuracies in the collection of turnstile data, allowing this data set to be the base for comparison. Collection intervals were randomly determined and demonstrated periods of slow, average, and heavy traffic. Results – After analyzing 1,039,766 patron visits throughout a year, the final totals only showed a difference of .43% (.0043 between the two devices. The majority of collection periods did not exceed a difference of 3% between the counting instruments. Conclusion – Turnstiles card readers and laser gate counters provide similar levels of reliability when measuring patron activity. Each system has potential counting inaccuracies, but several methods exist to create more precise totals. Turnstile card readers are capable of offering greater detail involving patron identity, but their high cost makes them inaccessible for libraries with lower budgets. This makes laser gate counters an affordable alternative for reliable patron counting in an academic library.

  4. Linear irreversible thermodynamics and Onsager reciprocity for information-driven engines

    Science.gov (United States)

    Yamamoto, Shumpei; Ito, Sosuke; Shiraishi, Naoto; Sagawa, Takahiro

    2016-11-01

    In the recent progress in nonequilibrium thermodynamics, information has been recognized as a kind of thermodynamic resource that can drive thermodynamic current without any direct energy injection. In this paper, we establish the framework of linear irreversible thermodynamics for a broad class of autonomous information processing. In particular, we prove that the Onsager reciprocity holds true with information: The linear response matrix is well-defined and is shown symmetric with both of the information affinity and the conventional thermodynamic affinity. As an application, we derive a universal bound for the efficiency at maximum power for information-driven engines in the linear regime. Our result reveals the fundamental role of information flow in linear irreversible thermodynamics.

  5. Mathematical models and equilibrium in irreversible microeconomics

    Directory of Open Access Journals (Sweden)

    Anatoly M. Tsirlin

    2010-07-01

    Full Text Available A set of equilibrium states in a system consisting of economic agents, economic reservoirs, and firms is considered. Methods of irreversible microeconomics are used. We show that direct sale/purchase leads to an equilibrium state which depends upon the coefficients of supply/demand functions. To reach the unique equilibrium state it is necessary to add either monetary exchange or an intermediate firm.

  6. Anistropically varying conductivity in irreversible electroporation simulations.

    Science.gov (United States)

    Labarbera, Nicholas; Drapaca, Corina

    2017-11-01

    One recent area of cancer research is irreversible electroporation (IRE). Irreversible electroporation is a minimally invasive procedure where needle electrodes are inserted into the body to ablate tumor cells with electricity. The aim of this paper is to propose a mathematical model that incorporates a tissue's conductivity increasing more in the direction of the electrical field as this has been shown to occur in experiments. It was necessary to mathematically derive a valid form of the conductivity tensor such that it is dependent on the electrical field direction and can be easily implemented into numerical software. The derivation of a conductivity tensor that can take arbitrary functions for the conductivity in the directions tangent and normal to the electrical field is the main contribution of this paper. Numerical simulations were performed for isotropic-varying and anisotropic-varying conductivities to evaluate the importance of including the electrical field's direction in the formulation for conductivity. By starting from previously published experimental results, this paper derived a general formulation for an anistropic-varying tensor for implementation into irreversible electroporation modeling software. The anistropic-varying tensor formulation allows the conductivity to take into consideration both electrical field direction and magnitude, as opposed to previous published works that only took into account electrical field magnitude. The anisotropic formulation predicts roughly a five percent decrease in ablation size for the monopolar simulation and approximately a ten percent decrease in ablation size for the bipolar simulations. This is a positive result as previously reported results found the isotropic formulation to overpredict ablation size for both monopolar and bipolar simulations. Furthermore, it was also reported that the isotropic formulation overpredicts the ablation size more for the bipolar case than the monopolar case. Thus, our

  7. Ecological optimization for an irreversible magnetic Ericsson refrigeration cycle

    International Nuclear Information System (INIS)

    Wang Hao; Wu Guo-Xing

    2013-01-01

    An irreversible Ericsson refrigeration cycle model is established, in which multi-irreversibilities such as finite-rate heat transfer, regenerative loss, heat leakage, and the efficiency of the regenerator are taken into account. Expressions for several important performance parameters, such as the cooling rate, coefficient of performance (COP), power input, exergy output rate, entropy generation rate, and ecological function are derived. The influences of the heat leakage and the time of the regenerative processes on the ecological performance of the refrigerator are analyzed. The optimal regions of the ecological function, cooling rate, and COP are determined and evaluated. Furthermore, some important parameter relations of the refrigerator are revealed and discussed in detail. The results obtained here have general significance and will be helpful in gaining a deep understanding of the magnetic Ericsson refrigeration cycle. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  8. Bacterial, fungal and yeast contamination in six brands of irreversible hydrocolloid impression materials Contaminação por bactérias, fungos e leveduras em seis marcas comerciais de materiais de moldagem à base de hidrocolóide irreversível

    OpenAIRE

    Luciana Assirati Casemiro; Carlos Henrique Gomes Martins; Fernanda de Carvalho Panzeri Pires de Souza; Heitor Panzeri; Isabel Yoko Ito

    2007-01-01

    This study assessed the level of contamination of six commercially available irreversible hydrocolloids (two containing chlorhexidine) and identified the contamination present in the materials. Petri dishes containing selective and enriched culture media were inoculated with alginate powder (0.06 g), in triplicate. After incubation (37°C/7 days), the colony-forming units (CFU) were counted and Gram stained. Biochemical identification of the different morphotypes was also performed. The co...

  9. Detailed Modeling and Irreversible Transfer Process Analysis of a Multi-Element Thermoelectric Generator System

    Science.gov (United States)

    Xiao, Heng; Gou, Xiaolong; Yang, Suwen

    2011-05-01

    Thermoelectric (TE) power generation technology, due to its several advantages, is becoming a noteworthy research direction. Many researchers conduct their performance analysis and optimization of TE devices and related applications based on the generalized thermoelectric energy balance equations. These generalized TE equations involve the internal irreversibility of Joule heating inside the thermoelectric device and heat leakage through the thermoelectric couple leg. However, it is assumed that the thermoelectric generator (TEG) is thermally isolated from the surroundings except for the heat flows at the cold and hot junctions. Since the thermoelectric generator is a multi-element device in practice, being composed of many fundamental TE couple legs, the effect of heat transfer between the TE couple leg and the ambient environment is not negligible. In this paper, based on basic theories of thermoelectric power generation and thermal science, detailed modeling of a thermoelectric generator taking account of the phenomenon of energy loss from the TE couple leg is reported. The revised generalized thermoelectric energy balance equations considering the effect of heat transfer between the TE couple leg and the ambient environment have been derived. Furthermore, characteristics of a multi-element thermoelectric generator with irreversibility have been investigated on the basis of the new derived TE equations. In the present investigation, second-law-based thermodynamic analysis (exergy analysis) has been applied to the irreversible heat transfer process in particular. It is found that the existence of the irreversible heat convection process causes a large loss of heat exergy in the TEG system, and using thermoelectric generators for low-grade waste heat recovery has promising potential. The results of irreversibility analysis, especially irreversible effects on generator system performance, based on the system model established in detail have guiding significance for

  10. Efficacy of supplementary buccal infiltrations and intraligamentary injections to inferior alveolar nerve blocks in mandibular first molars with asymptomatic irreversible pulpitis: a randomized controlled trial.

    Science.gov (United States)

    Parirokh, M; Sadr, S; Nakhaee, N; Abbott, P V; Askarifard, S

    2014-10-01

    This randomized double-blinded controlled trial was performed to compare the efficacy of inferior alveolar nerve block (IANB) injection for mandibular first molar teeth with irreversible pulpitis with or without supplementary buccal infiltration and intraligamentary injection. Eighty-two patients with asymptomatic irreversible pulpitis received either a combination of intraligamentary injection + buccal infiltration+ IANB or with traditional IANB injection in mandibular first molar teeth with irreversible pulpitis. Each patient recorded their pain score on a Heft-Parker visual analogue scale before commencing treatment, in response to a cold test 15 min after the designated anaesthetic injection, during access cavity preparation and during root canal instrumentation. No or mild pain at any stage was considered a success. Data were analysed by chi-square test. At the final stage of treatment, 69 of the 82 patients were eligible to be included in the study. No significant difference was found between age (P = 0.569) and gender (P = 0.570) amongst the patients in the two groups. The success rate of anaesthesia in the IANB and the combination groups were 22% and 58%, respectively. The success rate of anaesthesia in the combination group was significantly higher than the traditional IANB injection (P = 0.003). A combination of anaesthetic techniques can improve the success rate of anaesthesia for mandibular first molar teeth with irreversible pulpitis. © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  11. Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical trial.

    Science.gov (United States)

    Asgary, Saeed; Eghbal, Mohammad Jafar; Fazlyab, Mahta; Baghban, Alireza Akbarzadeh; Ghoddusi, Jamileh

    2015-03-01

    Previous reported results of up to 12 months as well as 24-month follow-ups revealed superior and equivalent treatment outcomes for vital pulp therapy (VPT) using calcium-enriched mixture cement (CEM) in comparison with root canal therapy (RCT) for mature molars with established irreversible pulpitis, respectively. Present non-inferiority multicenter randomized clinical trial assesses the final long-term (5-year) results as well as the effects of patients' age/gender and the presence of preoperative periapical lesion on the treatment outcomes. A total number of 407 patients were blindly allocated into two treatment groups [group 1 (VPT/CEM, n = 205) and group 2 (RCT, n = 202)] treated in 23 health-care centers by calibrated dentists. The treatment outcomes were assessed after 60 months. The 5-year results revealed no significant differences in the successes of both study arms (P = 0.29); a total number of 271 patients were available (~33 % were lost to follow-up). The patients' age/gender did not affect the outcomes; the presence of preoperative periapical lesion also did not implement a significant effect in both groups (P > 0.05). As an alternative for RCT, VPT/CEM can be considered as a valid treatment for vital mature permanent molars clinically diagnosed with irreversible pulpitis. Considering the favorable outcomes of 6- to 60-month follow-ups, as an evidence-based/simple/affordable/effective/biologic approach in cases of irreversible pulpitis, VPT/CEM is highly recommended for universal clinical practice.

  12. Irreversible JPEG 2000 compression of abdominal CT for primary interpretation: assessment of visually lossless threshold

    International Nuclear Information System (INIS)

    Lee, Kyoung Ho; Kim, Young Hoon; Kim, Bo Hyoung; Kim, Kil Joong; Kim, Tae Jung; Kim, Hyuk Jung; Hahn, Seokyung

    2007-01-01

    To estimate the visually lossless threshold for Joint Photographic Experts Group (JPEG) 2000 compression of contrast-enhanced abdominal computed tomography (CT) images, 100 images were compressed to four different levels: a reversible (as negative control) and irreversible 5:1, 10:1, and 15:1. By alternately displaying the original and the compressed image on the same monitor, six radiologists independently determined if the compressed image was distinguishable from the original image. For each reader, we compared the proportion of the compressed images being rated distinguishable from the original images between the reversible compression and each of the three irreversible compressions using the exact test for paired proportions. For each reader, the proportion was not significantly different between the reversible (0-1%, 0/100 to 1/100) and irreversible 5:1 compression (0-3%). However, the proportion significantly increased with the irreversible 10:1 (95-99%) and 15:1 compressions (100%) versus reversible compression in all readers (P < 0.001); 100 and 95% of the 5:1 compressed images were rated indistinguishable from the original images by at least five of the six readers and all readers, respectively. Irreversibly 5:1 compressed abdominal CT images are visually lossless and, therefore, potentially acceptable for primary interpretation. (orig.)

  13. Antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles.

    Science.gov (United States)

    Ginjupalli, Kishore; Alla, Rama Krishna; Tellapragada, Chaitanya; Gupta, Lokendra; Upadhya Perampalli, Nagaraja

    2016-06-01

    Conventional spray and the immersion disinfection of irreversible hydrocolloid impression materials may lead to dimensional changes. The purpose of this in vitro study was to investigate the antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles. The antimicrobial activity and properties of 2 commercially available irreversible hydrocolloid impression materials were evaluated after incorporating varying concentrations of silver nanoparticles. Antimicrobial activity was determined using the disk diffusion method. The gel strength, permanent deformation, flow, and gelation time were measured according to American Dental Association specification #18. Analysis of variance was used to identify the significant differences within and across the groups (α=.05). Adding silver nanoparticles to irreversible hydrocolloid impression materials resulted in superior antimicrobial activity without adversely affecting their properties. Adding silver nanoparticles to Zelgan significantly increased the gel strength compared with the control group, except at 5 wt%. However, the gel strength of Tropicalgin was unaffected except at 5 wt%. An increase in the permanent deformation was found with the incorporation of silver nanoparticles in both Zelgan and Tropicalgin. The flow of Zelgan increased with the incorporation of silver nanoparticles, whereas a decrease in the flow of Tropicalgin was observed at 1 wt% and 2 wt%. An increase in the gelation time of both Zelgan and Tropicalgin was observed with the incorporation of silver nanoparticles. Based on this in vitro study, silver nanoparticles can be incorporated into irreversible hydrocolloid impression materials as antimicrobial agents without adversely affecting their properties. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  14. Digital Counts of Maize Plants by Unmanned Aerial Vehicles (UAVs

    Directory of Open Access Journals (Sweden)

    Friederike Gnädinger

    2017-05-01

    Full Text Available Precision phenotyping, especially the use of image analysis, allows researchers to gain information on plant properties and plant health. Aerial image detection with unmanned aerial vehicles (UAVs provides new opportunities in precision farming and precision phenotyping. Precision farming has created a critical need for spatial data on plant density. The plant number reflects not only the final field emergence but also allows a more precise assessment of the final yield parameters. The aim of this work is to advance UAV use and image analysis as a possible high-throughput phenotyping technique. In this study, four different maize cultivars were planted in plots with different seeding systems (in rows and equidistantly spaced and different nitrogen fertilization levels (applied at 50, 150 and 250 kg N/ha. The experimental field, encompassing 96 plots, was overflown at a 50-m height with an octocopter equipped with a 10-megapixel camera taking a picture every 5 s. Images were recorded between BBCH 13–15 (it is a scale to identify the phenological development stage of a plant which is here the 3- to 5-leaves development stage when the color of young leaves differs from older leaves. Close correlations up to R2 = 0.89 were found between in situ and image-based counted plants adapting a decorrelation stretch contrast enhancement procedure, which enhanced color differences in the images. On average, the error between visually and digitally counted plants was ≤5%. Ground cover, as determined by analyzing green pixels, ranged between 76% and 83% at these stages. However, the correlation between ground cover and digitally counted plants was very low. The presence of weeds and blurry effects on the images represent possible errors in counting plants. In conclusion, the final field emergence of maize can rapidly be assessed and allows more precise assessment of the final yield parameters. The use of UAVs and image processing has the potential to

  15. Prostaglandin E2 to diagnose between reversible and irreversible pulpitis.

    Science.gov (United States)

    Petrini, M; Ferrante, M; Ciavarelli, L; Brunetti, L; Vacca, M; Spoto, G

    2012-01-01

    The aim of this work is to verify a correlation between the grade of inflammation and the concentration of PGE2 in human dental pulp. A total of 25 human dental pulps were examined by histological analysis and radioimmunologic dosage of PGE2. The pulps used in this experiment were from healthy and symptomatic teeth; the first ones were collected from teeth destined to be extracted for orthodontic reasons. An increase was observed of PGE2 in reversible pulpitis compared with healthy pulps and with the irreversible pulpitis and the clear decrease of these when NSAIDs are taken. This study demonstrates that PGE2 level is correlated to histological analysis thus allowing to distinguish symptomatic teeth in reversible and irreversible pulpitis.

  16. Compton suppression gamma-counting: The effect of count rate

    Science.gov (United States)

    Millard, H.T.

    1984-01-01

    Past research has shown that anti-coincidence shielded Ge(Li) spectrometers enhanced the signal-to-background ratios for gamma-photopeaks, which are situated on high Compton backgrounds. Ordinarily, an anti- or non-coincidence spectrum (A) and a coincidence spectrum (C) are collected simultaneously with these systems. To be useful in neutron activation analysis (NAA), the fractions of the photopeak counts routed to the two spectra must be constant from sample to sample to variations must be corrected quantitatively. Most Compton suppression counting has been done at low count rate, but in NAA applications, count rates may be much higher. To operate over the wider dynamic range, the effect of count rate on the ratio of the photopeak counts in the two spectra (A/C) was studied. It was found that as the count rate increases, A/C decreases for gammas not coincident with other gammas from the same decay. For gammas coincident with other gammas, A/C increases to a maximum and then decreases. These results suggest that calibration curves are required to correct photopeak areas so quantitative data can be obtained at higher count rates. ?? 1984.

  17. Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016).

    Science.gov (United States)

    Corazzi, Teresa; Leone, Mario; Maucci, Raffaella; Corazzi, Lanfranco; Gresele, Paolo

    2005-12-01

    Benzoic acid, 2-(acetyl-oxy)-3-[(nitrooxy)methyl]phenyl ester (NCX 4016), a new drug made by an aspirin molecule linked, through a spacer, to a nitric oxide (NO)-donating moiety, is now under clinical testing for the treatment of atherothrombotic conditions. Aspirin exerts its antithrombotic activity by irreversibly inactivating platelet cyclooxygenase (COX)-1. NCX 4016 in vivo undergoes metabolism into deacetylated and/or denitrated metabolites, and it is not known whether NCX 4016 needs to liberate aspirin to inhibit COX-1, or whether it can block it as a whole molecule. The aim of our study was to evaluate the effects of NCX 4016 and its analog or metabolites on platelet COX-1 and whole blood COX-2 and on purified ovine COX (oCOX)-1 and oCOX-2. In particular, we have compared the mechanism by which NCX 4016 inhibits purified oCOX enzymes with that of aspirin using a spectrophotometric assay. All the NCX 4016 derivatives containing acetylsalicylic acid inhibited the activity of oCOX-1 and oCOX-2, whereas the deacetylated metabolites and the nitric oxide-donating moiety were inactive. Dialysis experiments showed that oCOX-1 inhibition by NCX 4016, similar to aspirin, is irreversible. Reversible COX inhibitors (indomethacin) or salicylic acid incubated with the enzyme before NCX 4016 prevent the irreversible inhibition of oCOX-1 by NCX 4016 as well as by aspirin. In conclusion, our data show that NCX 4016 acts as a direct and irreversible inhibitor of COX-1 and that the presence of a spacer and NO-donating moiety in the molecule slows the kinetics of COX-1 inhibition by NCX 4016, compared with aspirin.

  18. EcoCount

    Directory of Open Access Journals (Sweden)

    Phillip P. Allen

    2014-05-01

    Full Text Available Techniques that analyze biological remains from sediment sequences for environmental reconstructions are well established and widely used. Yet, identifying, counting, and recording biological evidence such as pollen grains remain a highly skilled, demanding, and time-consuming task. Standard procedure requires the classification and recording of between 300 and 500 pollen grains from each representative sample. Recording the data from a pollen count requires significant effort and focused resources from the palynologist. However, when an adaptation to the recording procedure is utilized, efficiency and time economy improve. We describe EcoCount, which represents a development in environmental data recording procedure. EcoCount is a voice activated fully customizable digital count sheet that allows the investigator to continuously interact with a field of view during the data recording. Continuous viewing allows the palynologist the opportunity to remain engaged with the essential task, identification, for longer, making pollen counting more efficient and economical. EcoCount is a versatile software package that can be used to record a variety of environmental evidence and can be installed onto different computer platforms, making the adoption by users and laboratories simple and inexpensive. The user-friendly format of EcoCount allows any novice to be competent and functional in a very short time.

  19. RBC count

    Science.gov (United States)

    ... by kidney disease) RBC destruction ( hemolysis ) due to transfusion, blood vessel injury, or other cause Leukemia Malnutrition Bone ... slight risk any time the skin is broken) Alternative Names Erythrocyte count; Red blood cell count; Anemia - RBC count Images Blood test ...

  20. On the existence of physiological age based on functional hierarchy: a formal definition related to time irreversibility.

    Science.gov (United States)

    Chauvet, Gilbert A

    2006-09-01

    The present approach of aging and time irreversibility is a consequence of the theory of functional organization that I have developed and presented over recent years (see e.g., Ref. 11). It is based on the effect of physically small and numerous perturbations known as fluctuations, of structural units on the dynamics of the biological system during its adult life. Being a highly regulated biological system, a simple realistic hypothesis, the time-optimum regulation between the levels of organization, leads to the existence of an internal age for the biological system, and time-irreversibility associated with aging. Thus, although specific genes are controlling aging, time-irreversibility of the system may be shown to be due to the degradation of physiological functions. In other words, I suggest that for a biological system, the nature of time is specific and is an expression of the highly regulated integration. An internal physiological age reflects the irreversible course of a living organism towards death because of the irreversible course of physiological functions towards dysfunction, due to the irreversible changes in the regulatory processes. Following the works of Prigogine and his colleagues in physics, and more generally in the field of non-integrable dynamical systems (theorem of Poincaré-Misra), I have stated this problem in terms of the relationship between the macroscopic irreversibility of the functional organization and the basic mechanisms of regulation at the lowest "microscopic" level, i.e., the molecular, lowest level of organization. The neuron-neuron elementary functional interaction is proposed as an illustration of the method to define aging in the nervous system.

  1. First and Second-Law Efficiency Analysis and ANN Prediction of a Diesel Cycle with Internal Irreversibility, Variable Specific Heats, Heat Loss, and Friction Considerations

    Directory of Open Access Journals (Sweden)

    M. M. Rashidi

    2014-04-01

    Full Text Available The variability of specific heats, internal irreversibility, heat and frictional losses are neglected in air-standard analysis for different internal combustion engine cycles. In this paper, the performance of an air-standard Diesel cycle with considerations of internal irreversibility described by using the compression and expansion efficiencies, variable specific heats, and losses due to heat transfer and friction is investigated by using finite-time thermodynamics. Artificial neural network (ANN is proposed for predicting the thermal efficiency and power output values versus the minimum and the maximum temperatures of the cycle and also the compression ratio. Results show that the first-law efficiency and the output power reach their maximum at a critical compression ratio for specific fixed parameters. The first-law efficiency increases as the heat leakage decreases; however the heat leakage has no direct effect on the output power. The results also show that irreversibilities have depressing effects on the performance of the cycle. Finally, a comparison between the results of the thermodynamic analysis and the ANN prediction shows a maximum difference of 0.181% and 0.194% in estimating the thermal efficiency and the output power. The obtained results in this paper can be useful for evaluating and improving the performance of practical Diesel engines.

  2. Irreversible adsorption of particles on heterogeneous surfaces.

    Science.gov (United States)

    Adamczyk, Zbigniew; Jaszczółt, Katarzyna; Michna, Aneta; Siwek, Barbara; Szyk-Warszyńska, Lilianna; Zembala, Maria

    2005-12-30

    Methods of theoretical and experimental evaluation of irreversible adsorption of particles, e.g., colloids and globular proteins at heterogeneous surfaces were reviewed. The theoretical models were based on the generalized random sequential adsorption (RSA) approach. Within the scope of these models, localized adsorption of particles occurring as a result of short-ranged attractive interactions with discrete adsorption sites was analyzed. Monte-Carlo type simulations performed according to this model enabled one to determine the initial flux, adsorption kinetics, jamming coverage and the structure of the particle monolayer as a function of the site coverage and the particle/site size ratio, denoted by lambda. It was revealed that the initial flux increased significantly with the site coverage theta(s) and the lambda parameter. This behavior was quantitatively interpreted in terms of the scaled particle theory. It also was demonstrated that particle adsorption kinetics and the jamming coverage increased significantly, at fixed site coverage, when the lambda parameter increased. Practically, for alpha = lambda2theta(s) > 1 the jamming coverage at the heterogeneous surfaces attained the value pertinent to continuous surfaces. The results obtained prove unequivocally that spherically shaped sites were more efficient in binding particles in comparison with disk-shaped sites. It also was predicted that for particle size ratio lambda charge. Particle deposition occurred under diffusion-controlled transport conditions and their coverage was evaluated by direct particle counting using the optical and electron microscopy. Adsorption kinetics was quantitatively interpreted in terms of numerical solutions of the governing diffusion equation with the non-linear boundary condition derived from Monte-Carlo simulations. It was proven that for site coverage as low as a few percent the initial flux at heterogeneous surfaces attained the maximum value pertinent to homogeneous

  3. Pinning and irreversibility in superconducting bulk MgB{sub 2} with added nanodiamonds

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Anurag [Superconductivity and Cryogenics Division, National Physical Laboratory (CSIR), New Delhi-110012 (India); Narlikar, A V, E-mail: anurag@mail.nplindia.ernet.i [UGC-DAE Consortium for Scientific Research, University Campus, Khandwa Road, Indore-452017, MP (India)

    2009-12-15

    Resistance, R(T), and magnetization, M(B), studies on superconducting bulk MgB{sub 2} samples containing nanodiamonds (ND) as additives (wt% of ND: x = 0%, 1%, 3%, 5%, 7% and 10%) were recently published in two articles (Vajpayee et al 2007 Supercond. Sci. Technol. 20 S155, Vajpayee et al 2008 J. Appl. Phys. 103 07C708). The main observations reported were significant improvements in the critical current density J{sub c}(B), irreversibility line B{sub irr}(T) and upper critical field B{sub c2}(T) with ND addition. However, a closer look shows that as regards the potential of this technologically important material at higher magnetic fields and temperatures, there is still a lot of room for improvement. With that in mind we revisit the R(T) and M(B) data and analyze them, in the present work. We show that, despite ND addition, J{sub c} depends strongly on B in the high field region and tends to vanish at irreversibility lines that lie deep, i.e. at around 0.3 B{sub c2}(T), in the B-T phase diagram. The irreversibility lines, determined by R(T){yields}0 in the presence of B, are found to lie at around 0.5 B{sub c2}(T) in the phase diagram. These results for pinning and irreversibility lines are discussed in the light of various models such as those of surface sheath superconductivity, magnetically introduced percolation in polycrystalline MgB{sub 2}, thermally assisted flux motion (TAFM) and a modified flux line shear mechanism. Our analysis hints at TAFM and weak pinning channels with distributed superconducting properties percolating in our samples determining the irreversibility and pinning properties.

  4. Antibacterial efficacy and effect of chlorhexidine mixed with irreversible hydrocolloid for dental impressions: a randomized controlled trial.

    Science.gov (United States)

    Cubas, Glória; Valentini, Fernanda; Camacho, Guilherme Brião; Leite, Fábio; Cenci, Maximiliano Sérgio; Pereira-Cenci, Tatiana

    2014-01-01

    This study aimed to evaluate whether chlorhexidine mixed with irreversible hydrocolloid powder decreases microbial contamination during impression taking without affecting the resulting casts. Twenty volunteers were randomly divided into two groups (n = 10) according to the liquid used for impression taking in conjunction with irreversible hydrocolloid: 0.12% chlorhexidine or water. Surface roughness and dimensional stability of the casts were evaluated. Chlorhexidine mixed with irreversible hydrocolloid decreased the percentage of microorganisms when compared with water (P impression quality.

  5. Inequalities for trace anomalies, length of the RG flow, distance between the fixed points and irreversibility

    International Nuclear Information System (INIS)

    Anselmi, Damiano

    2004-01-01

    I discuss several issues about the irreversibility of the RG flow and the trace anomalies c, a and a'. First I argue that in quantum field theory: (i) the scheme-invariant area Δ a' of the graph of the effective beta function between the fixed points defines the length of the RG flow; (ii) the minimum of Δ a' in the space of flows connecting the same UV and IR fixed points defines the (oriented) distance between the fixed points and (iii) in even dimensions, the distance between the fixed points is equal to Δ a = a UV - a IR . In even dimensions, these statements imply the inequalities 0 ≤ Δ a ≤ Δ a' and therefore the irreversibility of the RG flow. Another consequence is the inequality a ≤ c for free scalars and fermions (but not vectors), which can be checked explicitly. Secondly, I elaborate a more general axiomatic set-up where irreversibility is defined as the statement that there exist no pairs of non-trivial flows connecting interchanged UV and IR fixed points. The axioms, based on the notions of length of the flow, oriented distance between the fixed points and certain 'oriented-triangle inequalities', imply the irreversibility of the RG flow without a global a function. I conjecture that the RG flow is also irreversible in odd dimensions (without a global a function). In support of this, I check the axioms of irreversibility in a class of d = 3 theories where the RG flow is integrable at each order of the large N expansion

  6. Irreversible thermodynamics, parabolic law and self-similar state in grain growth

    International Nuclear Information System (INIS)

    Rios, P.R.

    2004-01-01

    The formalism of the thermodynamic theory of irreversible processes is applied to grain growth to investigate the nature of the self-similar state and its corresponding parabolic law. Grain growth does not reach a steady state in the sense that the entropy production remains constant. However, the entropy production can be written as a product of two factors: a scale factor that tends to zero for long times and a scaled entropy production. It is suggested that the parabolic law and the self-similar state may be associated with the minimum of this scaled entropy production. This result implies that the parabolic law and the self-similar state have a sound irreversible thermodynamical basis

  7. Analysis of a compartmental model of amyloid beta production, irreversible loss and exchange in humans.

    Science.gov (United States)

    Elbert, Donald L; Patterson, Bruce W; Bateman, Randall J

    2015-03-01

    Amyloid beta (Aβ) peptides, and in particular Aβ42, are found in senile plaques associated with Alzheimer's disease. A compartmental model of Aβ production, exchange and irreversible loss was recently developed to explain the kinetics of isotope-labeling of Aβ peptides collected in cerebrospinal fluid (CSF) following infusion of stable isotope-labeled leucine in humans. The compartmental model allowed calculation of the rates of production, irreversible loss (or turnover) and short-term exchange of Aβ peptides. Exchange of Aβ42 was particularly pronounced in amyloid plaque-bearing participants. In the current work, we describe in much greater detail the characteristics of the compartmental model to two distinct audiences: physician-scientists and biokineticists. For physician-scientists, we describe through examples the types of questions the model can and cannot answer, as well as correct some misunderstandings of previous kinetic analyses applied to this type of isotope labeling data. For biokineticists, we perform a system identifiability analysis and a sensitivity analysis of the kinetic model to explore the global and local properties of the model. Combined, these analyses motivate simplifications from a more comprehensive physiological model to the final model that was previously presented. The analyses clearly demonstrate that the current dataset and compartmental model allow determination with confidence a single 'turnover' parameter, a single 'exchange' parameter and a single 'delay' parameter. When combined with CSF concentration data for the Aβ peptides, production rates may also be obtained. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. The universal power and efficiency characteristics for irreversible reciprocating heat engine cycles

    CERN Document Server

    Qin Xiao Yong; Sun Feng Rui; Wu Chih

    2003-01-01

    The performance of irreversible reciprocating heat engine cycles with heat transfer loss and friction-like term loss is analysed using finite-time thermodynamics. The universal relations between the power output and the compression ratio, between the thermal efficiency and the compression ratio, and the optimal relation between power output and the efficiency of the cycles are derived. Moreover, analysis and optimization of the model were carried out in order to investigate the effect of cycle processes on the performance of the cycle using numerical examples. The results obtained herein include the performance characteristics of irreversible reciprocating Diesel, Otto, Atkinson and Brayton cycles.

  9. A general nonlinear evolution equation for irreversible conservative approach to stable equilibrium

    International Nuclear Information System (INIS)

    Beretta, G.P.

    1986-01-01

    This paper addresses a mathematical problem relevant to the question of nonequilibrium and irreversibility, namely, that of ''designing'' a general evolution equation capable of describing irreversible but conservative relaxtion towards equilibrium. The objective is to present an interesting mathematical solution to this design problem, namely, a new nonlinear evolution equation that satisfies a set of very stringent relevant requirements. Three different frameworks are defined from which the new equation could be adopted, with entirely different interpretations. Some useful well-known mathematics involving Gram determinants are presented and a nonlinear evolution equation is given which meets the stringent design specifications

  10. Irreversibility analysis for gravity driven non-Newtonian liquid film along an inclined isothermal plate

    International Nuclear Information System (INIS)

    Makinde, O.D.

    2005-10-01

    In this paper, the first and second law of thermodynamics are employed in order to study the inherent irreversibility for a gravity driven non-Newtonian Ostwald-de Waele power law liquid film along an inclined isothermal plate. Based on some simplified assumptions, the governing equations are obtained and solved analytically. Expressions for fluid velocity, temperature, volumetric entropy generation numbers, irreversibility distribution ratio and the Bejan number are also determined. (author)

  11. Counting statistics in low level radioactivity measurements fluctuating counting efficiency

    International Nuclear Information System (INIS)

    Pazdur, M.F.

    1976-01-01

    A divergence between the probability distribution of the number of nuclear disintegrations and the number of observed counts, caused by counting efficiency fluctuation, is discussed. The negative binominal distribution is proposed to describe the probability distribution of the number of counts, instead of Poisson distribution, which is assumed to hold for the number of nuclear disintegrations only. From actual measurements the r.m.s. amplitude of counting efficiency fluctuation is estimated. Some consequences of counting efficiency fluctuation are investigated and the corresponding formulae are derived: (1) for detection limit as a function of the number of partial measurements and the relative amplitude of counting efficiency fluctuation, and (2) for optimum allocation of the number of partial measurements between sample and background. (author)

  12. Strategies for enumeration of circulating microvesicles on a conventional flow cytometer: Counting beads and scatter parameters.

    Science.gov (United States)

    Alkhatatbeh, Mohammad J; Enjeti, Anoop K; Baqar, Sara; Ekinci, Elif I; Liu, Dorothy; Thorne, Rick F; Lincz, Lisa F

    2018-01-01

    Enumeration of circulating microvesicles (MVs) by conventional flow cytometry is accomplished by the addition of a known amount of counting beads and calculated from the formula: MV/μl = (MV count/bead count) × final bead concentration. We sought to optimize each variable in the equation by determining the best parameters for detecting 'MV count' and examining the effects of different bead preparations and concentrations on the final calculation. Three commercially available bead preparations (TruCount, Flow-Count and CountBright) were tested, and MV detection on a BD FACSCanto was optimized for gating by either forward scatter (FSC) or side scatter (SSC); the results were compared by calculating different subsets of MV on a series of 74 typical patient plasma samples. The relationship between the number of beads added to each test and the number of beads counted by flow cytometry remained linear over a wide range of bead concentrations ( R 2 ≥ 0.997). However, TruCount beads produced the most consistent (concentration variation = 3.8%) calculated numbers of plasma CD41 + /Annexin V + MV, which were significantly higher from that calculated using either Flow-Count or CountBright ( p beads by FSC and 0.16 μm beads by SSC, but there were significantly more background events using SSC compared with FSC (3113 vs. 470; p = 0.008). In general, sample analysis by SSC resulted in significantly higher numbers of MV ( p beads provided linear results at concentrations ranging from 6 beads/μl to 100 beads/μl, but TruCount was the most consistent. Using SSC to gate MV events produced high background which negatively affected counting bead enumeration and overall MV calculations. Strategies to reduce SSC background should be employed in order to reliably use this technique.

  13. Treatise on irreversible and statistical thermodynamics an introduction to nonclassical thermodynamics

    CERN Document Server

    Yourgrau, Wolfgang; Raw, Gough

    2002-01-01

    Extensively revised edition of a much-respected work examines thermodynamics of irreversible processes, general principles of statistical thermodynamics, assemblies of noninteracting structureless particles, and statistical theory. 1966 edition.

  14. Influence of delayed pouring on irreversible hydrocolloid properties

    Directory of Open Access Journals (Sweden)

    Stéfani Becker Rodrigues

    2012-10-01

    Full Text Available The aim of this study was to evaluate the physical properties of irreversible hydrocolloid materials poured immediately and after different storage periods. Four alginates were tested: Color Change (Cavex; Hydrogum (Zhermack; Hydrogum 5 (Zhermack; and Hydro Print Premium (Coltene. Their physical properties, including the recovery from deformation (n = 3, compressive strength (n = 3, and detail reproduction and gypsum compatibility (n = 3, were analyzed according to ANSI/ADA specification no. 18. Specimens were stored at 23ºC and humidity and were then poured with gypsum immediately and after 1, 2, 3, 4, and 5 days. The data were analyzed by two-way analysis of variance (ANOVA and Tukey's test at p < 0.05. All of the alginate impression materials tested exhibited detail reproduction and gypsum compatibility at all times. Hydro Print Premium and Hydrogum 5 showed recovery from deformation, as established by ANSI/ADA specification no. 18, after 5 days of storage. As the storage time increased, the compressive strength values also increased. Considering the properties of compounds' recovery from deformation, compressive strength, and detail reproduction and gypsum compatibility, irreversible hydrocolloids should be poured immediately.

  15. Irreversible entropy model for damage diagnosis in resistors

    Energy Technology Data Exchange (ETDEWEB)

    Cuadras, Angel, E-mail: angel.cuadras@upc.edu; Crisóstomo, Javier; Ovejas, Victoria J.; Quilez, Marcos [Instrumentation, Sensor and Interfaces Group, Electronic Engineering Department, Escola d' Enginyeria de Telecomunicació i Aeronàutica de Castelldefels EETAC, Universitat Politècnica de Catalunya, Barcelona Tech (UPC), Castelldefels-Barcelona (Spain)

    2015-10-28

    We propose a method to characterize electrical resistor damage based on entropy measurements. Irreversible entropy and the rate at which it is generated are more convenient parameters than resistance for describing damage because they are essentially positive in virtue of the second law of thermodynamics, whereas resistance may increase or decrease depending on the degradation mechanism. Commercial resistors were tested in order to characterize the damage induced by power surges. Resistors were biased with constant and pulsed voltage signals, leading to power dissipation in the range of 4–8 W, which is well above the 0.25 W nominal power to initiate failure. Entropy was inferred from the added power and temperature evolution. A model is proposed to understand the relationship among resistance, entropy, and damage. The power surge dissipates into heat (Joule effect) and damages the resistor. The results show a correlation between entropy generation rate and resistor failure. We conclude that damage can be conveniently assessed from irreversible entropy generation. Our results for resistors can be easily extrapolated to other systems or machines that can be modeled based on their resistance.

  16. Irreversible entropy model for damage diagnosis in resistors

    International Nuclear Information System (INIS)

    Cuadras, Angel; Crisóstomo, Javier; Ovejas, Victoria J.; Quilez, Marcos

    2015-01-01

    We propose a method to characterize electrical resistor damage based on entropy measurements. Irreversible entropy and the rate at which it is generated are more convenient parameters than resistance for describing damage because they are essentially positive in virtue of the second law of thermodynamics, whereas resistance may increase or decrease depending on the degradation mechanism. Commercial resistors were tested in order to characterize the damage induced by power surges. Resistors were biased with constant and pulsed voltage signals, leading to power dissipation in the range of 4–8 W, which is well above the 0.25 W nominal power to initiate failure. Entropy was inferred from the added power and temperature evolution. A model is proposed to understand the relationship among resistance, entropy, and damage. The power surge dissipates into heat (Joule effect) and damages the resistor. The results show a correlation between entropy generation rate and resistor failure. We conclude that damage can be conveniently assessed from irreversible entropy generation. Our results for resistors can be easily extrapolated to other systems or machines that can be modeled based on their resistance

  17. Advanced Caries Microbiota in Teeth with Irreversible Pulpitis.

    Science.gov (United States)

    Rôças, Isabela N; Lima, Kenio C; Assunção, Isauremi V; Gomes, Patrícia N; Bracks, Igor V; Siqueira, José F

    2015-09-01

    Bacterial taxa in the forefront of caries biofilms are candidate pathogens for irreversible pulpitis and are possibly the first ones to invade the pulp and initiate endodontic infection. This study examined the microbiota of the most advanced layers of dentinal caries in teeth with irreversible pulpitis. DNA extracted from samples taken from deep dentinal caries associated with pulp exposures was analyzed for the presence and relative levels of 33 oral bacterial taxa by using reverse-capture checkerboard hybridization assay. Quantification of total bacteria, streptococci, and lactobacilli was also performed by using real-time quantitative polymerase chain reaction. Associations between the target bacterial taxa and clinical signs/symptoms were also evaluated. The most frequently detected taxa in the checkerboard assay were Atopobium genomospecies C1 (53%), Pseudoramibacter alactolyticus (37%), Streptococcus species (33%), Streptococcus mutans (33%), Parvimonas micra (13%), Fusobacterium nucleatum (13%), and Veillonella species (13%). Streptococcus species, Dialister invisus, and P. micra were significantly associated with throbbing pain, S. mutans with pain to percussion, and Lactobacillus with continuous pain (P pulpitis is suspected. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  18. Performance Optimization of a Solar-Driven Multi-Step Irreversible Brayton Cycle Based on a Multi-Objective Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    Ahmadi Mohammad Hosein

    2016-01-01

    Full Text Available An applicable approach for a multi-step regenerative irreversible Brayton cycle on the basis of thermodynamics and optimization of thermal efficiency and normalized output power is presented in this work. In the present study, thermodynamic analysis and a NSGA II algorithm are coupled to determine the optimum values of thermal efficiency and normalized power output for a Brayton cycle system. Moreover, three well-known decision-making methods are employed to indicate definite answers from the outputs gained from the aforementioned approach. Finally, with the aim of error analysis, the values of the average and maximum error of the results are also calculated.

  19. Energy Efficient Operation of Distillation Columns and a Reactor Applying Irreversible Thermodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Koeijer, Gelein M. de

    2002-05-01

    In this thesis the entropy production rates of diabatic distillation columns and a SO{sub 2} converter were minimised. This is the same as maximising the second law energy efficiency of the systems. The development of chemical industry can be made more sustainable by knowing this minimum. We found that the entropy production rate of distillation could be reduced up to 50 %. In order to achieve this reduction, heat exchangers were added on each tray. The characteristics of an optimum distillation column were presented. Furthermore, the entropy production rate of a SO{sub 2} converter was reduced with 16.7 % by altering the heights of catalytic beds, transfer areas of heat exchangers, and temperature differences over heat exchangers. These reductions show that there is still a large improvement potential in chemical industry. By applying the improved operations the world oil production can be reduced in the order of magnitude of 1 %. A similar reduction in the emission of the greenhouse gas CO{sub 2} can be expected. For deriving the entropy production rate in a systematic manner the theory of irreversible thermodynamics was useful. A simpler and a more complicated equation for the entropy production rate of distillation were derived. The simpler equation used only one force-flux product. It was suitable for minimisation of the entropy production rate of columns with the assumption of equilibrium between the outlets on each tray. The more complicated equation was able to describe satisfactorily the entropy production rate of an experimental column that separated the non-ideal mixture water-ethanol. It was next used to derive an extended set of transport equations for distillation, that includes the interface and the Soret effect (or thermal diffusion). Finally, irreversible thermodynamics was used to describe the contribution to the entropy production rate of heat transfer in heat exchangers. This contribution had a significant impact on the results of the

  20. Irreversibility and higher-spin conformal field theory

    Science.gov (United States)

    Anselmi, Damiano

    2000-08-01

    I discuss the properties of the central charges c and a for higher-derivative and higher-spin theories (spin 2 included). Ordinary gravity does not admit a straightforward identification of c and a in the trace anomaly, because it is not conformal. On the other hand, higher-derivative theories can be conformal, but have negative c and a. A third possibility is to consider higher-spin conformal field theories. They are not unitary, but have a variety of interesting properties. Bosonic conformal tensors have a positive-definite action, equal to the square of a field strength, and a higher-derivative gauge invariance. There exists a conserved spin-2 current (not the canonical stress tensor) defining positive central charges c and a. I calculate the values of c and a and study the operator-product structure. Higher-spin conformal spinors have no gauge invariance, admit a standard definition of c and a and can be coupled to Abelian and non-Abelian gauge fields in a renormalizable way. At the quantum level, they contribute to the one-loop beta function with the same sign as ordinary matter, admit a conformal window and non-trivial interacting fixed points. There are composite operators of high spin and low dimension, which violate the Ferrara-Gatto-Grillo theorem. Finally, other theories, such as conformal antisymmetric tensors, exhibit more severe internal problems. This research is motivated by the idea that fundamental quantum field theories should be renormalization-group (RG) interpolations between ultraviolet and infrared conformal fixed points, and quantum irreversibility should be a general principle of nature.

  1. Microbiome of Deep Dentinal Caries Lesions in Teeth with Symptomatic Irreversible Pulpitis.

    Science.gov (United States)

    Rôças, Isabela N; Alves, Flávio R F; Rachid, Caio T C C; Lima, Kenio C; Assunção, Isauremi V; Gomes, Patrícia N; Siqueira, José F

    2016-01-01

    This study used a next-generation sequencing approach to identify the bacterial taxa occurring in the advanced front of caries biofilms associated with pulp exposure and irreversible pulpitis. Samples were taken from the deepest layer of dentinal caries lesions associated with pulp exposure in 10 teeth diagnosed with symptomatic irreversible pulpitis. DNA was extracted and the microbiome was characterized on the basis of the V4 hypervariable region of the 16S rRNA gene by using paired-end sequencing on Illumina MiSeq device. Bacterial taxa were mapped to 14 phyla and 101 genera composed by 706 different OTUs. Three phyla accounted for approximately 98% of the sequences: Firmicutes, Actinobacteria and Proteobacteria. These phyla were also the ones with most representatives at the species level. Firmicutes was the most abundant phylum in 9/10 samples. As for genera, Lactobacillus accounted for 42.3% of the sequences, followed by Olsenella (13.7%), Pseudoramibacter (10.7%) and Streptococcus (5.5%). Half of the samples were heavily dominated by Lactobacillus, while in the other half lactobacilli were in very low abundance and the most dominant genera were Pseudoramibacter, Olsenella, Streptococcus, and Stenotrophomonas. High bacterial diversity occurred in deep dentinal caries lesions associated with symptomatic irreversible pulpitis. The microbiome could be classified according to the relative abundance of Lactobacillus. Except for Lactobacillus species, most of the highly prevalent and abundant bacterial taxa identified in this study have been commonly detected in infected root canals. The detected taxa can be regarded as candidate pathogens for irreversible pulpitis and possibly the pioneers in pulp invasion to initiate endodontic infection.

  2. Microbiome of Deep Dentinal Caries Lesions in Teeth with Symptomatic Irreversible Pulpitis.

    Directory of Open Access Journals (Sweden)

    Isabela N Rôças

    Full Text Available This study used a next-generation sequencing approach to identify the bacterial taxa occurring in the advanced front of caries biofilms associated with pulp exposure and irreversible pulpitis. Samples were taken from the deepest layer of dentinal caries lesions associated with pulp exposure in 10 teeth diagnosed with symptomatic irreversible pulpitis. DNA was extracted and the microbiome was characterized on the basis of the V4 hypervariable region of the 16S rRNA gene by using paired-end sequencing on Illumina MiSeq device. Bacterial taxa were mapped to 14 phyla and 101 genera composed by 706 different OTUs. Three phyla accounted for approximately 98% of the sequences: Firmicutes, Actinobacteria and Proteobacteria. These phyla were also the ones with most representatives at the species level. Firmicutes was the most abundant phylum in 9/10 samples. As for genera, Lactobacillus accounted for 42.3% of the sequences, followed by Olsenella (13.7%, Pseudoramibacter (10.7% and Streptococcus (5.5%. Half of the samples were heavily dominated by Lactobacillus, while in the other half lactobacilli were in very low abundance and the most dominant genera were Pseudoramibacter, Olsenella, Streptococcus, and Stenotrophomonas. High bacterial diversity occurred in deep dentinal caries lesions associated with symptomatic irreversible pulpitis. The microbiome could be classified according to the relative abundance of Lactobacillus. Except for Lactobacillus species, most of the highly prevalent and abundant bacterial taxa identified in this study have been commonly detected in infected root canals. The detected taxa can be regarded as candidate pathogens for irreversible pulpitis and possibly the pioneers in pulp invasion to initiate endodontic infection.

  3. Extended irreversible thermodynamics and the Jeffreys type constitutive equations

    International Nuclear Information System (INIS)

    Serdyukov, S.I.

    2003-01-01

    A postulate of extended irreversible thermodynamics is considered, according to which the entropy density is a function of the internal energy, the specific volume, and their material time derivatives. On the basis of this postulate, entropy balance equations and phenomenological equations are obtained, which directly lead to the Jeffreys type constitutive equations

  4. Determining random counts in liquid scintillation counting

    International Nuclear Information System (INIS)

    Horrocks, D.L.

    1979-01-01

    During measurements involving coincidence counting techniques, errors can arise due to the detection of chance or random coincidences in the multiple detectors used. A method and the electronic circuits necessary are here described for eliminating this source of error in liquid scintillation detectors used in coincidence counting. (UK)

  5. Effects of irreversibility and economics on the performance of a heat engine

    International Nuclear Information System (INIS)

    Ibrahim, O.M.; Klein, S.A.; Mitchell, J.W.

    1992-01-01

    In this paper, optimization of the power output of an internally irreversible heat engine is considered for finite capacitance rates of the external fluid streams. The method of Lagrange multipliers is used to solve for working fluid temperatures which yield maximum power. Analytical expressions for the maximum power and the cycle efficiency at miximum power are obtained. The effects of irreversibility and economics on the performance of a heat engine are investigated. A relationship between the maximum power point and economically optimum design is identified. It is demonstrated that, with certain reasonable economic assumptions, the maximum power point of a heat engine corresponds to a point of minimum life-cycle costs

  6. Eutectic cell and nodule count as the quality factors of cast iron

    Directory of Open Access Journals (Sweden)

    E. Fraś

    2008-10-01

    Full Text Available In this work the predictions based on a theoretical analysis aimed at elucidating of eutectic cell count or nodule counts N wereexperimentally verified. The experimental work was focused on processing flake graphite and ductile iron under various inoculationconditions in order to achieve various physicochemical states of the experimental melts. In addition, plates of various wall thicknesses, s were cast and the resultant eutectic cell or nodule counts were established. Moreover, thermal analysis was used to find out the degree of maximum undercooling for the graphite eutectic, Tm. A relationship was found between the eutectic cell or nodule count and the maximum undercooling Tm.. In addition it was also found that N can be related to the wall thickness of plate shaped castings. Finally, the present work provides a rational for the effect of technological factors such as the melt chemistry, inoculation practice, and holding temperature and time on the resultant cell count or nodule count of cast iron. In particular, good agreement was found between the predictions of the theoretical analysis and the experimental data.

  7. Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer.

    Science.gov (United States)

    Liu, Bing; Huang, XinPing; Hu, YunLong; Chen, TingTing; Peng, BoYa; Gao, NingNing; Jin, ZhenChao; Jia, TieLiu; Zhang, Na; Wang, ZhuLin; Jin, GuangYi

    2016-09-06

    Prolonged treatment of breast cancer with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) often results in acquired resistance and a narrow therapeutic index. One strategy to improve the therapeutic effects of EGFR TKIs is to combine them with drugs used for other clinical indications. Ethacrynic acid (EA) is an FDA approved drug that may have antitumor effects and may enhance the cytotoxicity of chemotherapeutic agents by binding to glutathione and inhibiting WNT signaling. While the α,β-unsaturated-keto structure of EA is similar to that of irreversible TKIs, the mechanism of action of EA when combined with irreversible EGFR TKIs in breast cancer remains unknown. We therefore investigated the combination of irreversible EGFR TKIs and EA. We found that irreversible EGFR TKIs and EA synergistically inhibit breast cancer both in vitro and in vivo. The combination of EGFR TKIs and EA induces necrosis and cell cycle arrest and represses WNT/β-catenin signaling as well as MAPK-ERK1/2 signaling. We conclude that EA synergistically enhances the antitumor effects of irreversible EGFR TKIs in breast cancer.

  8. Positive Feedback of NDT80 Expression Ensures Irreversible Meiotic Commitment in Budding Yeast

    Science.gov (United States)

    Tsuchiya, Dai; Yang, Yang; Lacefield, Soni

    2014-01-01

    In budding yeast, meiotic commitment is the irreversible continuation of the developmental path of meiosis. After reaching meiotic commitment, cells finish meiosis and gametogenesis, even in the absence of the meiosis-inducing signal. In contrast, if the meiosis-inducing signal is removed and the mitosis-inducing signal is provided prior to reaching meiotic commitment, cells exit meiosis and return to mitosis. Previous work has shown that cells commit to meiosis after prophase I but before entering the meiotic divisions. Since the Ndt80 transcription factor induces expression of middle meiosis genes necessary for the meiotic divisions, we examined the role of the NDT80 transcriptional network in meiotic commitment. Using a microfluidic approach to analyze single cells, we found that cells commit to meiosis in prometaphase I, after the induction of the Ndt80-dependent genes. Our results showed that high-level expression of NDT80 is important for the timing and irreversibility of meiotic commitment. A modest reduction in NDT80 levels delayed meiotic commitment based on meiotic stages, although the timing of each meiotic stage was similar to that of wildtype cells. A further reduction of NDT80 resulted in the surprising finding of inappropriately uncommitted cells: withdrawal of the meiosis-inducing signal and addition of the mitosis-inducing signal to cells at stages beyond metaphase I caused return to mitosis, leading to multi-nucleate cells. Since Ndt80 enhances its own transcription through positive feedback, we tested whether positive feedback ensured the irreversibility of meiotic commitment. Ablating positive feedback in NDT80 expression resulted in a complete loss of meiotic commitment. These findings suggest that irreversibility of meiotic commitment is a consequence of the NDT80 transcriptional positive feedback loop, which provides the high-level of Ndt80 required for the developmental switch of meiotic commitment. These results also illustrate the

  9. Radiation counting statistics

    Energy Technology Data Exchange (ETDEWEB)

    Suh, M. Y.; Jee, K. Y.; Park, K. K.; Park, Y. J.; Kim, W. H

    1999-08-01

    This report is intended to describe the statistical methods necessary to design and conduct radiation counting experiments and evaluate the data from the experiment. The methods are described for the evaluation of the stability of a counting system and the estimation of the precision of counting data by application of probability distribution models. The methods for the determination of the uncertainty of the results calculated from the number of counts, as well as various statistical methods for the reduction of counting error are also described. (Author). 11 refs., 8 tabs., 8 figs.

  10. Radiation counting statistics

    Energy Technology Data Exchange (ETDEWEB)

    Suh, M. Y.; Jee, K. Y.; Park, K. K. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-08-01

    This report is intended to describe the statistical methods necessary to design and conduct radiation counting experiments and evaluate the data from the experiments. The methods are described for the evaluation of the stability of a counting system and the estimation of the precision of counting data by application of probability distribution models. The methods for the determination of the uncertainty of the results calculated from the number of counts, as well as various statistical methods for the reduction of counting error are also described. 11 refs., 6 figs., 8 tabs. (Author)

  11. Radiation counting statistics

    International Nuclear Information System (INIS)

    Suh, M. Y.; Jee, K. Y.; Park, K. K.; Park, Y. J.; Kim, W. H.

    1999-08-01

    This report is intended to describe the statistical methods necessary to design and conduct radiation counting experiments and evaluate the data from the experiment. The methods are described for the evaluation of the stability of a counting system and the estimation of the precision of counting data by application of probability distribution models. The methods for the determination of the uncertainty of the results calculated from the number of counts, as well as various statistical methods for the reduction of counting error are also described. (Author). 11 refs., 8 tabs., 8 figs

  12. Dimensional Stability of Color-Changing Irreversible Hydrocolloids after Disinfection

    Directory of Open Access Journals (Sweden)

    Khaledi AAR

    2015-03-01

    Full Text Available Statement of Problem: Disinfection of dental impressions is a weak point in the dental hygiene chain. In addition, dental office personnel and dental technicians are endangered by cross-contamination. Objectives: This study aimed to investigate the dimensional stability of two color-changing irreversible hydrocolloid materials (IH after disinfection with glutaraldehyde. Materials and Methods: In this in vitro study, impressions were made of a master maxillary arch containing three reference inserts on the occlucal surface of the left and right maxillary second molars and in the incisal surface of the maxillary central incisors. Two types of color-changing irreversible hydrocolloid (tetrachrom, cavex were used. Glutaraldehyde 2% was used in two methods of spraying and immersion to disinfect the impressions. The control group was not disinfected. Casts were made of type IV gypsum. The linear dimensional change of the stone casts was measured with a profile projector. For statistical analysis, Kruskall-Wallis and Mann-Witney tests were used (α=0.05. Results: By immersion method, the casts fabricated from tetrachrom were 0.36% larger in the anteroposterior (AP and 0.05% smaller in cross arch (CA dimensions; however, the casts prepared after spraying of tetrachrom were 0.44% larger in the AP and 0.10% smaller in CA dimensions. The casts made from Cavex were 0.05% smaller in the AP and 0.02% smaller in CA dimensions after spraying and 0.01% smaller in the AP and 0.003% smaller in CA dimensions after immersion. Generally there were not significant differences in AP and CA dimensions of the experimental groups compared to the control (p > 0.05. Conclusions: Disinfection of the tested color-changing irreversible hydrocolloids by glutaraldahyde 2% did not compromise the accuracy of the obtained casts.

  13. Behavior of the irreversibility line in the new superconductor La1.5+xBa1.5+x-yCayCu3Oz

    International Nuclear Information System (INIS)

    Parra Vargas, C.A.; Pimentel, J.L.; Pureur, P.; Landínez Téllez, D.A.; Roa-Rojas, J.

    2012-01-01

    The irreversibility properties of high-T c superconductors are of major importance for technological applications. For example, a high irreversibility magnetic field is a more desirable quality for a superconductor . The irreversibility line in the H-T plane is constituted by experimental points, which divides the irreversible and reversible behavior of the magnetization. The irreversibility lines for series of La 1.5+x Ba 1.5+x-y Ca y Cu 3 O z polycrystalline samples with different doping were investigated. The samples were synthesized using the usual solid estate reaction method. Rietveld-type refinement of x-ray diffraction patterns permitted to determine the crystallization of material in a tetragonal structure. Curves of magnetization ZFC-FC for the system La 1.5+x Ba 1.5+x-y Ca y Cu 3 O z , were measured in magnetic fields of the 10-20,000 Oe, and allowed to obtain the values for the irreversibility and critical temperatures. The data of irreversibility temperature allowed demarcating the irreversibility line, T irr (H). Two main lines are used for the interpretation of the irreversibility line: one of those which suppose that the vortexes are activated thermally and the other proposes that associated to T irr a phase transition occurs. The irreversibility line is described by a power law. The obtained results allow concluding that in the system La 1.5+x Ba 1.5+x-y Ca y Cu 3 O z a characteristic bend of the Almeida-Thouless (AT) tendency is dominant for low fields and a bend Gabay-Toulouse (GT) behavior for high magnetic fields. This feature of the irreversibility line has been reported as a characteristic of granular superconductors and it corroborates the topological effects of vortexes mentioned by several authors .

  14. Magnetic irreversibility in granular superconductors: ac susceptibility study

    International Nuclear Information System (INIS)

    Perez, F.; Obradors, X.; Fontcuberta, J.; Vallet, M.; Gonzalez-Calbet, J.

    1991-01-01

    Ac susceptibility measurements of a ceramic weak-coupled superconductor in very low ac fields (2mG, 111Hz) are reported. We present evidence for the observation of the magnetic irreversibility following a ZFC-FC thermal cycling by means of ac susceptibilty measurements. It is shown that this technique also reflect local magnetic field effects in granular superconductors, as previously suggested in microwave surface resistance and I-V characteristics. (orig.)

  15. Effect of disinfection on irreversible hydrocolloid and alternative impression materials and the resultant gypsum casts.

    Science.gov (United States)

    Suprono, Montry S; Kattadiyil, Mathew T; Goodacre, Charles J; Winer, Myron S

    2012-10-01

    Many new products have been introduced and marketed as alternatives to traditional irreversible hydrocolloid materials. These alternative materials have the same structural formula as addition reaction silicone, also known as vinyl polysiloxane (VPS), impression materials. Currently, there is limited in vitro and in vivo research on these products, including on the effects of chemical disinfectants on the materials. The purpose of this study was to compare the effects of a spray disinfecting technique on a traditional irreversible hydrocolloid and 3 new alternative impression materials in vitro. The tests were performed in accordance with the American National Standards Institute/American Dental Association (ANSI/ADA) Specification Nos. 18 and 19. Under standardized conditions, 100 impressions were made of a ruled test block with an irreversible hydrocolloid and 3 alternative impression materials. Nondisinfected irreversible hydrocolloid was used as the control. The impressions were examined for surface detail reproduction before and after disinfection with a chloramine-T product. Type III and Type V dental stone casts were evaluated for linear dimensional change and gypsum compatibility. Comparisons of linear dimensional change were analyzed with 2-way ANOVA of mean ranks with the Scheffé post hoc comparisons (α=.05). Data for surface detail reproduction were analyzed with the Wilcoxon Signed-Rank procedure and gypsum compatibility with the Kruskal-Wallis Rank procedure (α=.05). The alternative impression materials demonstrated significantly better outcomes with all 3 parameters tested. Disinfection with chloroamine-T did not have any effect on the 3 alternative impression materials. The irreversible hydrocolloid groups produced the most variability in the measurements of linear dimensional change. All of the tested materials were within the ADA's acceptable limit of 1.0% for linear dimensional change, except for the disinfected irreversible hydrocolloid

  16. Irreversible dilation of NaCl contaminated lime-cement mortar due to crystallization cycles

    International Nuclear Information System (INIS)

    Lubelli, B.; Hees, R.P.J. van; Huinink, H.P.; Groot, C.J.W.P.

    2006-01-01

    The mechanism of damage occurring in NaCl contaminated materials has not been clarified yet. Apart from crystallization pressure, other hypotheses have been proposed to explain the cause of decay. Irreversible dilation has been observed in a few cases but has never been studied in a more systematic way. The aim of the research is to contribute to the modeling of this phenomenon. In the present paper the effect of NaCl on the hydric and hygric behavior of a lime-cement mortar is extensively studied. The results indicate that NaCl influences the hydric and hygric dilation behavior of the material. The material contaminated with NaCl shrinks during dissolution and dilates during crystallization of the salt. This dilation is irreversible and sufficient to damage the material after few dissolution/crystallization cycles. This behavior is not restricted to NaCl, but is observed in the presence of other salts as well (NaNO 3 and KCl). Outcomes of electron microscopy studies suggest that salts causing irreversible dilation tend to crystallize as layers on the pore wall

  17. Tower counts

    Science.gov (United States)

    Woody, Carol Ann; Johnson, D.H.; Shrier, Brianna M.; O'Neal, Jennifer S.; Knutzen, John A.; Augerot, Xanthippe; O'Neal, Thomas A.; Pearsons, Todd N.

    2007-01-01

    Counting towers provide an accurate, low-cost, low-maintenance, low-technology, and easily mobilized escapement estimation program compared to other methods (e.g., weirs, hydroacoustics, mark-recapture, and aerial surveys) (Thompson 1962; Siebel 1967; Cousens et al. 1982; Symons and Waldichuk 1984; Anderson 2000; Alaska Department of Fish and Game 2003). Counting tower data has been found to be consistent with that of digital video counts (Edwards 2005). Counting towers do not interfere with natural fish migration patterns, nor are fish handled or stressed; however, their use is generally limited to clear rivers that meet specific site selection criteria. The data provided by counting tower sampling allow fishery managers to determine reproductive population size, estimate total return (escapement + catch) and its uncertainty, evaluate population productivity and trends, set harvest rates, determine spawning escapement goals, and forecast future returns (Alaska Department of Fish and Game 1974-2000 and 1975-2004). The number of spawning fish is determined by subtracting subsistence, sport-caught fish, and prespawn mortality from the total estimated escapement. The methods outlined in this protocol for tower counts can be used to provide reasonable estimates ( plus or minus 6%-10%) of reproductive salmon population size and run timing in clear rivers. 

  18. Unifying principles of irreversibility minimization for efficiency maximization in steady-flow chemically-reactive engines

    International Nuclear Information System (INIS)

    Ramakrishnan, Sankaran; Edwards, Christopher F.

    2014-01-01

    Systems research has led to the conception and development of various steady-flow, chemically-reactive, engine cycles for stationary power generation and propulsion. However, the question that remains unanswered is: What is the maximum-efficiency steady-flow chemically-reactive engine architecture permitted by physics? On the one hand the search for higher-efficiency cycles continues, often involving newer processes and devices (fuel cells, carbon separation, etc.); on the other hand the design parameters for existing cycles are continually optimized in response to improvements in device engineering. In this paper we establish that any variation in engine architecture—parametric change or process-sequence change—contributes to an efficiency increase via one of only two possible ways to minimize total irreversibility. These two principles help us unify our understanding from a large number of parametric analyses and cycle-optimization studies for any steady-flow chemically-reactive engine, and set a framework to systematically identify maximum-efficiency engine architectures. - Highlights: • A unified thermodynamic model to study chemically-reactive engine architectures is developed. • All parametric analyses of efficiency are unified by two irreversibility-minimization principles. • Variations in internal energy transfers yield a net work increase that is greater than engine irreversibility reduced. • Variations in external energy transfers yield a net work increase that is lesser than engine irreversibility reduced

  19. Antibacterial efficacy and effect of Morinda citrifolia L. mixed with irreversible hydrocolloid for dental impressions: A randomized controlled trial.

    Science.gov (United States)

    Ahmed, A Shafath; Charles, P David; Cholan, R; Russia, M; Surya, R; Jailance, L

    2015-08-01

    This study aimed to evaluate whether the extract of Morinda citrifolia L. mixed with irreversible hydrocolloid powder decreases microbial contamination during impression making without affecting the resulting casts. Twenty volunteers were randomly divided into two groups (n = 10). Group A 30 ml extract of M. citrifolia L diluted in 30 ml of water was mixed to make the impression with irreversible hydrocolloid material. Group B 30 ml deionized water was mixed with irreversible hydrocolloid material to make the impressions following which the surface roughness and dimensional stability of casts were evaluated. Extract of M. citrifolia L. mixed with irreversible hydrocolloid decreased the percentage of microorganisms when compared with water (P impression quality.

  20. Phase control of light amplification with dynamically irreversible pathways of population transfer in a Λ system

    International Nuclear Information System (INIS)

    Yuan Shi; Wu Jinhui; Gao Jinyue; Pan Chunliu

    2002-01-01

    We use the relative phase of two coherent fields for the control of light amplification with dynamically irreversible pathways of population transfer in a Λ system. The population inversion and gain with dynamically irreversible pathways of population transfer are shown as the relative phase is varied. We support our results by numerical calculation and analytical explanation

  1. Pacific Ciguatoxin Induces Excitotoxicity and Neurodegeneration in the Motor Cortex Via Caspase 3 Activation: Implication for Irreversible Motor Deficit.

    Science.gov (United States)

    Asthana, Pallavi; Zhang, Ni; Kumar, Gajendra; Chine, Virendra Bhagawan; Singh, Kunal Kumar; Mak, Yim Ling; Chan, Leo Lai; Lam, Paul Kwan Sing; Ma, Chi Him Eddie

    2018-01-18

    Consumption of fish containing ciguatera toxins or ciguatoxins (CTXs) causes ciguatera fish poisoning (CFP). In some patients, CFP recurrence occurs even years after exposure related to CTXs accumulation. Pacific CTX-1 (P-CTX-1) is one of the most potent natural substances known that causes predominantly neurological symptoms in patients; however, the underlying pathogenies of CFP remain unknown. Using clinically relevant neurobehavioral tests and electromyography (EMG) to assess effects of P-CTX-1 during the 4 months after exposure, recurrent motor strength deficit occurred in mice exposed to P-CTX-1. We detected irreversible motor strength deficits accompanied by reduced EMG activity, demyelination, and slowing of motor nerve conduction, whereas control unexposed mice fully recovered in 1 month after peripheral nerve injury. Finally, to uncover the mechanism underlying CFP, we detected reduction of spontaneous firing rate of motor cortical neurons even 6 months after exposure and increased number of glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes. Increased numbers of motor cortical neuron apoptosis were detected by dUTP-digoxigenin nick end labeling assay along with activation of caspase 3. Taken together, our study demonstrates that persistence of P-CTX-1 in the nervous system induces irreversible motor deficit that correlates well with excitotoxicity and neurodegeneration detected in the motor cortical neurons.

  2. Extended irreversible thermodynamics and non-equilibrium temperature

    Directory of Open Access Journals (Sweden)

    Casas-Vazquez, Jose'

    2008-02-01

    Full Text Available We briefly review the concept of non-equilibrium temperature from the perspectives of extended irreversible thermodynamics, fluctuation theory, and statistical mechanics. The relations between different proposals are explicitly examined in two especially simple systems: an ideal gas in steady shear flow and a forced harmonic oscillator in a thermal bath. We examine with special detail temperatures related to the average molecular kinetic energy along different spatial directions, to the average configurational energy, to the derivative of the entropy with respect to internal energy, to fluctuation-dissipation relation and discuss their measurement.

  3. Statistical mechanics out of equilibrium the irreversibility

    International Nuclear Information System (INIS)

    Alvarez Estrada, R. F.

    2001-01-01

    A Round Table about the issue of Irreversibility and related matters has taken place during the last (20th) Statistical Mechanics Conference, held in Paris (July 1998). This article tries to provide a view (necessarily limited, and hence, uncompleted) of some approaches to the subject: the one based upon deterministic chaos (which is currently giving rise to a very active research) and the classical interpretation due to Boltzmann. An attempt has been made to write this article in a self-contained way, and to avoid a technical presentation wherever possible. (Author) 29 refs

  4. Transition from reversible to irreversible magnetic exchange-spring processes in antiferromagnetically exchange-coupled hard/soft/hard trilayer structures

    International Nuclear Information System (INIS)

    Wang Xiguang; Guo Guanghua; Zhang Guangfu

    2011-01-01

    The demagnetization processes of antiferromagnetically exchange-coupled hard/soft/hard trilayer structures have been studied based on the discrete one-dimensional atomic chain model and the linear partial domain-wall model. It is found that, when the magnetic anisotropy of soft layer is taken into account, the changes of the soft layer thickness and the interfacial exchange coupling strength may lead a transition of demagnetization process in soft layer from the reversible to the irreversible magnetic exchange-spring process. For the trilayer structures with very thin soft layer, the demagnetization process exhibits typical reversible exchange-spring behavior. However, as the thickness of soft layer is increased, there is a crossover point t c , after which the process becomes irreversible. Similarly, there is also a critical interfacial exchange coupling constant A sh c , above which the exchange-spring process is reversible. When A sh sh c , the irreversible exchange-spring process is achieved. The phase diagram of reversible and irreversible exchange-spring processes is mapped in the plane of the interfacial exchange coupling A sh and soft layer thickness N s . - Research highlights: → A differing magnetic exchange-spring process is found in antiferromagnetically exchange-coupled hard/soft/hard trilayers if the magnetic anisotropy of the soft layers is taken into account. → The change of the soft layer thickness may lead to a transition of demagnetization process in soft layer from the reversible to the irreversible exchange-spring process. → The change of the soft-hard interfacial exchange coupling strength may lead a transition of demagnetization process in soft layer from the reversible to the irreversible exchange-spring process. → The phase diagram of reversible and irreversible exchange-spring processes is mapped in the plane of the interfacial exchange coupling and soft layer thickness.

  5. Understanding Irreversible Degradation of Nb3Sn Wires with Fundamental Fracture Mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Yuhu [PPPL; Calzolaio, Ciro [Univ of Geneva; Senatore, Carmine [Univ of Geneva

    2014-08-01

    Irreversible performance degradation of advanced Nb3Sn superconducting wires subjected to transverse or axial mechanical loading is a critical issue for the design of large-scale fusion and accelerator magnets such as ITER and LHC. Recent SULTAN tests indicate that most cable-in-conduit conductors for ITER coils made of Nb3Sn wires processed by various fabrication techniques show similar performance degradation under cyclic loading. The irreversible degradation due to filament fracture and local strain accumulation in Nb3Sn wires cannot be described by the existing strand scaling law. Fracture mechanic modeling combined with X-ray diffraction imaging of filament micro-crack formation inside the wires under mechanical loading may reveal exciting insights to the wire degradation mechanisms. We apply fundamental fracture mechanics with a singularity approach to study influence of wire filament microstructure of initial void size and distribution to local stress concentration and potential crack propagation. We report impact of the scale and density of the void structure on stress concentration in the composite wire materials for crack initiation. These initial defects result in an irreversible degradation of the critical current beyond certain applied stress. We also discuss options to minimize stress concentration in the design of the material microstructure for enhanced wire performance for future applications.

  6. Counting carbohydrates

    Science.gov (United States)

    Carb counting; Carbohydrate-controlled diet; Diabetic diet; Diabetes-counting carbohydrates ... Many foods contain carbohydrates (carbs), including: Fruit and fruit juice Cereal, bread, pasta, and rice Milk and milk products, soy milk Beans, legumes, ...

  7. Repeatability of differential goat bulk milk culture and associations with somatic cell count, total bacterial count, and standard plate count

    OpenAIRE

    Koop, G.; Dik, N.; Nielen, M.; Lipman, L.J.A.

    2010-01-01

    The aims of this study were to assess how different bacterial groups in bulk milk are related to bulk milk somatic cell count (SCC), bulk milk total bacterial count (TBC), and bulk milk standard plate count (SPC) and to measure the repeatability of bulk milk culturing. On 53 Dutch dairy goat farms, 3 bulk milk samples were collected at intervals of 2 wk. The samples were cultured for SPC, coliform count, and staphylococcal count and for the presence of Staphylococcus aureus. Furthermore, SCC ...

  8. Efficacy of Articaine and Lidocaine for Buccal Infiltration of First Maxillary Molars with Symptomatic Irreversible Pulpitis: A Randomized Double-blinded Clinical Trial

    Science.gov (United States)

    Hosseini, Hamid Reza; Parirokh, Masoud; Nakhaee, Nouzar; V. Abbott, Paul; Samani, Syamak

    2016-01-01

    Introduction: The aim of the present study was to compare the efficacy of 2% lidocaine to 4% articaine in buccal infiltration of maxillary first molars with irreversible pulpitis. Moreover, the effect of root length on success of anesthesia irrespective of the type of anesthetic agent was assessed. Methods and Materials: Fifty patients suffering from painful maxillary first molars with irreversible pulpitis received an infiltration injection of either 4% articaine with 1:100000 epinephrine or 2% lidocaine with 1:80000 epinephrine. Each patient recorded their pain score in response to a cold test on a Heft-Parker visual analogue scale (VAS) before commencing the treatment, 5 min following injection, during access preparation, after pulp exposure and during root canal instrumentation. No or mild pain at any stage was considered a success. Data were analyzed using the multivariate logistic regression analysis, chi-square and t tests. Results: Finally, 47 out of 50 patients were eligible to be included in this study. The anesthetic success rates in the lidocaine and articaine groups were 56.52% and 66.67%, respectively and the difference was not significant (P=0.474). Irrespective of the anesthetic agent, the length of the palatal root (Odds Ratio=0.24, P=0.007) had an adverse effect on anesthetic success. There was an association between longer palatal root length and anesthetic failure. Conclusion: No significant difference was found between 2% lidocaine and 4% articaine in terms of anesthetic success in maxillary first molars with irreversible pulpitis. The length of the palatal root had a significant negative influence on anesthetic success. PMID:27141212

  9. Determining the complex modulus of alginate irreversible hydrocolloid dental material.

    Science.gov (United States)

    King, Shalinie; See, Howard; Thomas, Graham; Swain, Michael

    2008-11-01

    The aim of the study is to investigate the visco-elastic response of an alginate irreversible hydrocolloid dental impression material during setting. A novel squeeze film Micro-Fourier Rheometer (MFR, GBC Scientific Equipment, Australia) was used to determine the complex modulus of an alginate irreversible hydrocolloid dental impression material (Algident, ISO 1563 Class A Type 1, Dentalfarm Australia Pty. Ltd.) during setting after mixing. Data was collected every 30s for 10 min in one study and every 10 min for a total of 60 min in another study. A high level of repeatability was observed. The results indicate that the MFR is capable of recording the complex shear modulus of alginate irreversible hydrocolloid for 60 min from the start of mixing and to simultaneously report the changing visco-elastic parameters at all frequencies between 1 Hz and 100 Hz. The storage modulus shows a dramatic increase to 370% of its starting value after 6 min and then reduces to 55% after 60 min. The loss modulus increases to a maximum of 175% of its starting value after 10 min and then reduces to 94% after 60 min. The MFR enables the changes in the complex modulus through the complete setting process to be followed. It is anticipated this approach may provide a better method to compare the visco-elastic properties of impression materials and assist with identification of optimum types for different clinical requirements. The high stiffness of the instrument and the use of band-limited pseudo-random noise as the input signal are the main advantages of this technique over conventional rheometers for determining the changes in alginate visco-elasticity.

  10. Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with symptomatic versus asymptomatic irreversible pulpitis.

    Science.gov (United States)

    Argueta-Figueroa, Liliana; Arzate-Sosa, Gabriel; Mendieta-Zeron, Hugo

    2012-01-01

    This study sought to determine the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine in patients with symptomatic and asymptomatic irreversible pulpitis in mandibular posterior teeth and if individual patient factors, pulpal disease characteristics, and previous medication are correlated to local anesthetic success. A second objective was to determine the specificity and sensibility of a cold test for prediction of anesthetic success prior to endodontic treatment. Seventy patients diagnosed with irreversible pulpitis in mandibular posterior teeth received 1.6 mL of 4% articaine with 1:100,000 epinephrine for an inferior alveolar nerve block (IANB) using a metal guide. The anesthetic solution was injected with a computer-preprogrammed delivery system for local anesthesia. Endodontic access was begun 15 minutes after solution deposition; later, patients rated their discomfort using the visual analog scale (VAS). The success rate for the IA NB using articaine was 64.2% in patients with symptomatic irreversible pulpitis and 86.9% in patients with asymptomatic irreversible pulpitis. Cold test prior to root canal treatment had a specificity and sensibility of 12.5% and 87.1%, respectively. The anesthetic efficacy of articaine in irreversible pulpitis is moderately acceptable, and anesthetic success increases when the patient has been premedicated with NSAIDs. The cold test appears to be a favorable indicator for predicting anesthetic success.

  11. Lagrangian formulation of irreversible thermodynamics and the second law of thermodynamics.

    Science.gov (United States)

    Glavatskiy, K S

    2015-05-28

    We show that the equations which describe irreversible evolution of a system can be derived from a variational principle. We suggest a Lagrangian, which depends on the properties of the normal and the so-called "mirror-image" system. The Lagrangian is symmetric in time and therefore compatible with microscopic reversibility. The evolution equations in the normal and mirror-imaged systems are decoupled and describe therefore independent irreversible evolution of each of the systems. The second law of thermodynamics follows from a symmetry of the Lagrangian. Entropy increase in the normal system is balanced by the entropy decrease in the mirror-image system, such that there exists an "integral of evolution" which is a constant. The derivation relies on the property of local equilibrium, which states that the local relations between the thermodynamic quantities in non-equilibrium are the same as in equilibrium.

  12. The analysis of irreversibility, uncertainty and dynamic technical inefficiency on the investment decision in the Spanish olive sector

    NARCIS (Netherlands)

    Lambarraa, Fatima; Stefanou, Spiro; Gil, José M.

    2016-01-01

    This study addresses irreversible investment decision-making in the context of uncertainty when allowing for inefficiency to be transmitted over time. Both irreversibility and persistence in technical inefficiency can lead to sluggish adjustment of quasi-fixed factors of production. The context

  13. Revisiting the Glansdorff–Prigogine criterion for stability within irreversible thermodynamics

    Czech Academy of Sciences Publication Activity Database

    Maes, C.; Netočný, Karel

    2015-01-01

    Roč. 159, č. 6 (2015), s. 1286-1299 ISSN 0022-4715 R&D Projects: GA ČR GAP204/12/0897 Institutional support: RVO:68378271 Keywords : irreversible processes * thermodynamic stability * excess entropy production * nonequilibrium free energy * Clausius heat theorem Subject RIV: BE - Theoretical Physics Impact factor: 1.537, year: 2015

  14. Counting on dis-inhibition: a circuit motif for interval counting and selectivity in the anuran auditory system.

    Science.gov (United States)

    Naud, Richard; Houtman, Dave; Rose, Gary J; Longtin, André

    2015-11-01

    Information can be encoded in the temporal patterning of spikes. How the brain reads these patterns is of general importance and represents one of the greatest challenges in neuroscience. We addressed this issue in relation to temporal pattern recognition in the anuran auditory system. Many species of anurans perform mating decisions based on the temporal structure of advertisement calls. One important temporal feature is the number of sound pulses that occur with a species-specific interpulse interval. Neurons representing this pulse count have been recorded in the anuran inferior colliculus, but the mechanisms underlying their temporal selectivity are incompletely understood. Here, we construct a parsimonious model that can explain the key dynamical features of these cells with biologically plausible elements. We demonstrate that interval counting arises naturally when combining interval-selective inhibition with pulse-per-pulse excitation having both fast- and slow-conductance synapses. Interval-dependent inhibition is modeled here by a simple architecture based on known physiology of afferent nuclei. Finally, we consider simple implementations of previously proposed mechanistic explanations for these counting neurons and show that they do not account for all experimental observations. Our results demonstrate that tens of millisecond-range temporal selectivities can arise from simple connectivity motifs of inhibitory neurons, without recourse to internal clocks, spike-frequency adaptation, or appreciable short-term plasticity. Copyright © 2015 the American Physiological Society.

  15. Clustering method for counting passengers getting in a bus with single camera

    Science.gov (United States)

    Yang, Tao; Zhang, Yanning; Shao, Dapei; Li, Ying

    2010-03-01

    Automatic counting of passengers is very important for both business and security applications. We present a single-camera-based vision system that is able to count passengers in a highly crowded situation at the entrance of a traffic bus. The unique characteristics of the proposed system include, First, a novel feature-point-tracking- and online clustering-based passenger counting framework, which performs much better than those of background-modeling-and foreground-blob-tracking-based methods. Second, a simple and highly accurate clustering algorithm is developed that projects the high-dimensional feature point trajectories into a 2-D feature space by their appearance and disappearance times and counts the number of people through online clustering. Finally, all test video sequences in the experiment are captured from a real traffic bus in Shanghai, China. The results show that the system can process two 320×240 video sequences at a frame rate of 25 fps simultaneously, and can count passengers reliably in various difficult scenarios with complex interaction and occlusion among people. The method achieves high accuracy rates up to 96.5%.

  16. Quantum degeneracy effect on performance of irreversible Otto cycle with ideal Bose gas

    International Nuclear Information System (INIS)

    Wu Feng; Chen Lingen; Sun Fengrui; Wu Chih; Guo Fangzhong; Li Qing

    2006-01-01

    An Otto cycle working with an ideal Bose gas is called a Bose Otto cycle. The internal irreversibility of the cycle is included in the factors of internal irreversibility degree. The quantum degeneracy effect on the performance of the cycle is investigated based on quantum statistical mechanics and thermodynamics. Variations of the maximum work output ratio R W and the efficiency ratio y with temperature ratio τ are examined, which reveal the influence of the quantum degeneracy of the working substance on the performance of a Bose Otto cycle. It is shown that the results obtained herein are valid under both classical and quantum ideal gas conditions

  17. Evaluation of properties of irreversible hydrocolloid impression materials mixed with disinfectant liquids

    Directory of Open Access Journals (Sweden)

    Arul Amalan

    2013-01-01

    Conclusion: Chlorhexidine solution can be used to mix irreversible hydrocolloid impression materials in regular dental practice as it did not significantly alter the properties. This may ensure effective disinfection of impressions.

  18. Irreversibility in room temperature current–voltage characteristics of NiFe_2O_4 nanoparticles: A signature of electrical memory effect

    International Nuclear Information System (INIS)

    Dey, P.; Debnath, Rajesh; Singh, Swati; Mandal, S.K.; Roy, J.N.

    2017-01-01

    Room temperature I–V characteristics study, both in presence and absence of magnetic field (1800 Oe), has been performed on NiFe_2O_4 nanoparticles, having different particle size (φ~14, 21 and 31 nm). Our experiments on these nanoparticles provide evidences for: (1) electrical irreversibility or hysteretic behaviour; (2) positive magnetoresistance and (3) magnetic field dependent electrical irreversibility or hysteresis in the sample. “Hysteretic” nature of I–V curve reveals the existence of electrical memory effect in the sample. Significantly, such hysteresis has been found to be tuned by magnetic field. In order to explain the observed electrical irreversibility, we have proposed a phenomenological model on the light of induced polarization in the sample. Both the positive magnetoresistance and the observed magnetic field dependence of electrical irreversibility have been explained through magnetostriction phenomenon. Interestingly, such effects are found to get reduced with increasing particle size. For NiFe_2O_4 nanoparticles having φ=31 nm, we did not observe any irreversibility effect. This feature has been attributed to the enhanced grain surface effect that in turn gives rise to the residual polarization and hence electrical memory effect in NiFe_2O_4 nanoparticles, having small nanoscopic particle size. - Highlights: • I-V characteristics study of NiFe_2O_4 nanoparticles with varying particle sizes. • Experiments evident electrical hysteretic behaviour, i.e., electrical memory effect. • Magnetic field dependent electrical irreversibility is due to magnetostriction. • A phenomenological model has been proposed on the light of induced polarization. • Such electrical irreversibility decreases with increasing particle sizes.

  19. Model for an irreversible bias current in the superconducting qubit measurement process

    International Nuclear Information System (INIS)

    Hutchinson, G. D.; Williams, D. A.; Holmes, C. A.; Stace, T. M.; Spiller, T. P.; Barrett, S. D.; Milburn, G. J.; Hasko, D. G.

    2006-01-01

    The superconducting charge-phase ''quantronium'' qubit is considered in order to develop a model for the measurement process used in the experiment of Vion et al. [Science 296, 886 (2002)]. For this model we propose a method for including the bias current in the readout process in a fundamentally irreversible way, which to first order is approximated by the Josephson junction tilted-washboard potential phenomenology. The decohering bias current is introduced in the form of a Lindblad operator and the Wigner function for the current-biased readout Josephson junction is derived and analyzed. During the readout current pulse used in the quantronium experiment we find that the coherence of the qubit initially prepared in a symmetric superposition state is lost at a time of 0.2 ns after the bias current pulse has been applied, a time scale that is much shorter than the experimental readout time. Additionally we look at the effect of Johnson-Nyquist noise with zero mean from the current source during the qubit manipulation and show that the decoherence due to the irreversible bias current description is an order of magnitude smaller than that found through adding noise to the reversible tilted-washboard potential model. Our irreversible bias current model is also applicable to persistent-current-based qubits where the state is measured according to its flux via a small-inductance direct-current superconducting quantum interference device

  20. How Effective Is Supplemental Intraseptal Anesthesia in Patients with Symptomatic Irreversible Pulpitis?

    Science.gov (United States)

    Webster, Stephen; Drum, Melissa; Reader, Al; Fowler, Sara; Nusstein, John; Beck, Mike

    2016-10-01

    Previous studies have reported high levels of success with intraseptal injection for various dental procedures but provide limited information on the use of the injection during endodontic treatment. Therefore, the purpose of this prospective study was to determine the anesthetic efficacy of the supplemental intraseptal technique in mandibular posterior teeth diagnosed with symptomatic irreversible pulpitis when the conventional inferior alveolar nerve (IAN) block failed. One hundred patients with a diagnosis of symptomatic irreversible pulpitis in a mandibular posterior tooth were recruited. Following profound lip numbness after the administration of the conventional IAN block, endodontic treatment was initiated. Patients still experiencing moderate to severe pain during treatment were administered mesial and distal supplemental intraseptal injections using 0.7 mL 4% articaine with 1:000,000 epinephrine administered with a computer-controlled local anesthetic delivery unit. Success was defined as the ability to perform endodontic access and instrumentation with mild to no pain. Success with the IAN block was achieved in 25% of patients. Supplemental intraseptal injections provided success in 29% of patients. Supplemental intraseptal injections achieved profound pulpal anesthesia in 29% of patients when the IAN block failed. This low level of success would not provide predictable levels of anesthesia for patients requiring emergency endodontic treatment for symptomatic irreversible pulpitis in mandibular posterior teeth. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  1. Standardization of 241Am by digital coincidence counting, liquid scintillation counting and defined solid angle counting

    International Nuclear Information System (INIS)

    Balpardo, C.; Capoulat, M.E.; Rodrigues, D.; Arenillas, P.

    2010-01-01

    The nuclide 241 Am decays by alpha emission to 237 Np. Most of the decays (84.6%) populate the excited level of 237 Np with energy of 59.54 keV. Digital coincidence counting was applied to standardize a solution of 241 Am by alpha-gamma coincidence counting with efficiency extrapolation. Electronic discrimination was implemented with a pressurized proportional counter and the results were compared with two other independent techniques: Liquid scintillation counting using the logical sum of double coincidences in a TDCR array and defined solid angle counting taking into account activity inhomogeneity in the active deposit. The results show consistency between the three methods within a limit of a 0.3%. An ampoule of this solution will be sent to the International Reference System (SIR) during 2009. Uncertainties were analysed and compared in detail for the three applied methods.

  2. Benjamin Thompson, Count Rumford Count Rumford on the nature of heat

    CERN Document Server

    Brown, Sanborn C

    1967-01-01

    Men of Physics: Benjamin Thompson - Count Rumford: Count Rumford on the Nature of Heat covers the significant contributions of Count Rumford in the fields of physics. Count Rumford was born with the name Benjamin Thompson on March 23, 1753, in Woburn, Massachusetts. This book is composed of two parts encompassing 11 chapters, and begins with a presentation of Benjamin Thompson's biography and his interest in physics, particularly as an advocate of an """"anti-caloric"""" theory of heat. The subsequent chapters are devoted to his many discoveries that profoundly affected the physical thought

  3. Correction of the counting up number by dead time in detector systems for radiograph images

    International Nuclear Information System (INIS)

    Cerdeira E, A.; Cicuttin, A.; Cerdeira, A.; Estrada, M.; Luca, A. de

    2002-01-01

    The effect of the dead time in a detection system by counting up of particles and the contribution of this error in the final image resolution is analysed. It is given a statistical criteria for the optimization of electronic parameters such as dead time and counting up memory which help in the implementation of these systems with the minimum necessary characteristics which satisfy the resolution requirements. (Author)

  4. Data process of liquid scintillation counting

    International Nuclear Information System (INIS)

    Ishikawa, Hiroaki; Kuwajima, Susumu.

    1975-01-01

    The use of liquid scintillation counting system has been significantly spread because automatic sample changers and printers have recently come to be incorporated. However, the system will be systematized completely if automatic data processing and the sample preparation of radioactive materials to be measured are realized. Dry or wet oxidation method is applied to the sample preparation when radioactive materials are hard to dissolve into scintillator solution. Since these several years, the automatic sample combustion system, in which the dry oxidation is automated, has been rapidly spread and serves greatly to labor saving. Since the printers generally indicate only counted number, data processing system has been developed, and speeded up calculating process, which automatically corrects quenching of samples for obtaining the final radioactivity required. The data processing system is roughly divided into on-line and off-line systems according to whether computers are connected directly or indirectly, while its hardware is classified to input, calculating and output devices. Also, the calculation to determine sample activity by external standard method is explained. (Wakatsuki, Y.)

  5. Synergetcs - a field beyond irreversible thermodynamics

    International Nuclear Information System (INIS)

    Haken, H.

    1978-01-01

    This lecture introduces the reader to synergetics, a very young field of interdisciplinary research, which is devoted to the question of self-organization and, quite generally, to the birth of new qualities. After comparing the role of thermodynamics, irreversible thermodynamics and synergetics in the description of phenomena we give a few examples for self-oragnizing systems. Next we outline the mathematical approach and consider the generalized Ginzburg-Landau equations for non equilibrium phase transitions. We continue by applying these equations to the problem of morphogenesis in biology. We close our lecture by extending the formalism to spatially inhomogeneous or oscillating systems and arrive at order-parameter equations which are capable of describing new large classes of higher bifurcation schemes. (HJ)

  6. Capital dissipation minimization for a class of complex irreversible resource exchange processes

    Science.gov (United States)

    Xia, Shaojun; Chen, Lingen

    2017-05-01

    A model of a class of irreversible resource exchange processes (REPes) between a firm and a producer with commodity flow leakage from the producer to a competitive market is established in this paper. The REPes are assumed to obey the linear commodity transfer law (LCTL). Optimal price paths for capital dissipation minimization (CDM) (it can measure economic process irreversibility) are obtained. The averaged optimal control theory is used. The optimal REP strategy is also compared with other strategies, such as constant-firm-price operation and constant-commodity-flow operation, and effects of the amount of commodity transferred and the commodity flow leakage on the optimal REP strategy are also analyzed. The commodity prices of both the producer and the firm for the CDM of the REPes with commodity flow leakage change with the time exponentially.

  7. Irreversible thermodynamics of dark energy on the entropy-corrected apparent horizon

    Energy Technology Data Exchange (ETDEWEB)

    Karami, K; Sahraei, N [Department of Physics, University of Kurdistan, Pasdaran Street, Sanandaj (Iran, Islamic Republic of); Jamil, M, E-mail: KKarami@uok.ac.i, E-mail: mjamil@camp.nust.edu.p [Center for Advanced Mathematics and Physics (CAMP), National University of Sciences and Technology (NUST), Islamabad (Pakistan)

    2010-10-15

    We study the irreversible (non-equilibrium) thermodynamics of the Friedmann-Robertson-Walker (FRW) universe containing only dark energy. Using the modified entropy-area relation that is motivated by loop quantum gravity, we calculate the entropy-corrected form of the apparent horizon of the FRW universe.

  8. Pulpitis irreversible como forma de presentación de un odontoma

    OpenAIRE

    Berástegui, Esther; Buenechea Imaz, Ramón

    1997-01-01

    Se presenta un caso de odontoma compuesto que provocó pulpitis irreversible en el incisivo central superior derecho (1,1) en una joven de 20 años. El tratamiento fue la biopulpectomía total y extirpación quirúrgica del tumor.

  9. Counting cormorants

    DEFF Research Database (Denmark)

    Bregnballe, Thomas; Carss, David N; Lorentsen, Svein-Håkon

    2013-01-01

    This chapter focuses on Cormorant population counts for both summer (i.e. breeding) and winter (i.e. migration, winter roosts) seasons. It also explains differences in the data collected from undertaking ‘day’ versus ‘roost’ counts, gives some definitions of the term ‘numbers’, and presents two...

  10. Study of the irreversible trapping of dihydrogen with the use of a MnO2/Ag2O mixture

    International Nuclear Information System (INIS)

    Galliez, K.

    2012-01-01

    The hydrogen risk generated by radiolysis of organic compounds during a nuclear waste transport is a major issue. The use of irreversible getters is considered to limit this risk. The aim of this work is to study one of these getters, MnO 2 /Ag 2 O, in order to better understand the trapping phenomenon and to ensure its reliability. Initially several parameters affecting the trapping kinetics were studied. It has been shown that among all MnO 2 allotropic phases, the nsutite has the best trapping kinetics. Moreover, specific surface area and defect amount in MnO 2 can enhance trapping performances. Ag 2 O weight percentage (acting as promotor) has been determined at 13% to have the best trapping kinetics. Chemisorption of H 2 , which is required for its application, has been shown by using several characterization techniques such as magnetometry, infrared spectroscopy and electronic energy loss spectroscopy. The trapping irreversibility and the regeneration of the getter have been demonstrated respectively under nitrogen or air at 150 C. Finally, proton insertion mechanism in MnO 2 has been elucidated by pairs distribution function analysis through the development of a model to simulate the complex structure of MnO 2 . It has been shown that Ag 2 O is turned into Ag 2 CO 3 during the preparation of the getter under water, which has never been demonstrated. (author) [fr

  11. A Vision-Based Counting and Recognition System for Flying Insects in Intelligent Agriculture

    Directory of Open Access Journals (Sweden)

    Yuanhong Zhong

    2018-05-01

    Full Text Available Rapid and accurate counting and recognition of flying insects are of great importance, especially for pest control. Traditional manual identification and counting of flying insects is labor intensive and inefficient. In this study, a vision-based counting and classification system for flying insects is designed and implemented. The system is constructed as follows: firstly, a yellow sticky trap is installed in the surveillance area to trap flying insects and a camera is set up to collect real-time images. Then the detection and coarse counting method based on You Only Look Once (YOLO object detection, the classification method and fine counting based on Support Vector Machines (SVM using global features are designed. Finally, the insect counting and recognition system is implemented on Raspberry PI. Six species of flying insects including bee, fly, mosquito, moth, chafer and fruit fly are selected to assess the effectiveness of the system. Compared with the conventional methods, the test results show promising performance. The average counting accuracy is 92.50% and average classifying accuracy is 90.18% on Raspberry PI. The proposed system is easy-to-use and provides efficient and accurate recognition data, therefore, it can be used for intelligent agriculture applications.

  12. Short communication: Repeatability of differential goat bulk milk culture and associations with somatic cell count, total bacterial count, and standard plate count.

    Science.gov (United States)

    Koop, G; Dik, N; Nielen, M; Lipman, L J A

    2010-06-01

    The aims of this study were to assess how different bacterial groups in bulk milk are related to bulk milk somatic cell count (SCC), bulk milk total bacterial count (TBC), and bulk milk standard plate count (SPC) and to measure the repeatability of bulk milk culturing. On 53 Dutch dairy goat farms, 3 bulk milk samples were collected at intervals of 2 wk. The samples were cultured for SPC, coliform count, and staphylococcal count and for the presence of Staphylococcus aureus. Furthermore, SCC (Fossomatic 5000, Foss, Hillerød, Denmark) and TBC (BactoScan FC 150, Foss) were measured. Staphylococcal count was correlated to SCC (r=0.40), TBC (r=0.51), and SPC (r=0.53). Coliform count was correlated to TBC (r=0.33), but not to any of the other variables. Staphylococcus aureus did not correlate to SCC. The contribution of the staphylococcal count to the SPC was 31%, whereas the coliform count comprised only 1% of the SPC. The agreement of the repeated measurements was low. This study indicates that staphylococci in goat bulk milk are related to SCC and make a significant contribution to SPC. Because of the high variation in bacterial counts, repeated sampling is necessary to draw valid conclusions from bulk milk culturing. 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  13. Scale-dependent associations of Band-tailed Pigeon counts at mineral sites

    Science.gov (United States)

    Overton, Cory T.; Casazza, Michael L.; Coates, Peter S.

    2010-01-01

    The abundance of Band-tailed Pigeons (Patagioenas fasciata monilis) has declined substantially from historic numbers along the Pacific Coast. Identification of patterns and causative factors of this decline are hampered because habitat use data are limited, and temporal and spatial variability patterns associated with population indices are not known. Furthermore, counts are influenced not only by pigeon abundance but also by rate of visitation to mineral sites, which may not be consistent. To address these issues, we conducted mineral site counts during 2001 and 2002 at 20 locations from 4 regions in the Pacific Northwest, including central Oregon and western Washington, USA, and British Columbia, Canada. We developed inference models that consisted of environmental factors and spatial characteristics at multiple spatial scales. Based on information theory, we compared models within a final set that included variables measured at 3 spatial scales (0.03 ha, 3.14 ha, and 7850 ha). Pigeon counts increased from central Oregon through northern Oregon and decreased into British Columbia. After accounting for this spatial pattern, we found that pigeon counts increased 12% ± 2.7 with a 10% increase in the amount of deciduous forested area within 100 m from a mineral site. Also, distance from the mineral site of interest to the nearest known mineral site was positively related to pigeon counts. These findings provide direction for future research focusing on understanding the relationships between indices of relative abundance and complete counts (censuses) of pigeon populations by identifying habitat characteristics that might influence visitation rates. Furthermore, our results suggest that spatial arrangement of mineral sites influences Band-tailed Pigeon counts and the populations which those counts represent.

  14. Is thermodynamic irreversibility a consequence of the expansion of the Universe?

    Science.gov (United States)

    Osváth, Szabolcs

    2018-02-01

    This paper explains thermodynamic irreversibility by applying the expansion of the Universe to thermodynamic systems. The effect of metric expansion is immeasurably small on shorter scales than intergalactic distances. Multi-particle systems, however, are chaotic, and amplify any small disturbance exponentially. Metric expansion gives rise to time-asymmetric behaviour in thermodynamic systems in a short time (few nanoseconds in air, few ten picoseconds in water). In contrast to existing publications, this paper explains without any additional assumptions the rise of thermodynamic irreversibility from the underlying reversible mechanics of particles. Calculations for the special case which assumes FLRW metric, slow motions (v ≪ c) and approximates space locally by Euclidean space show that metric expansion causes entropy increase in isolated systems. The rise of time-asymmetry, however, is not affected by these assumptions. Any influence of the expansion of the Universe on the local metric causes a coupling between local mechanics and evolution of the Universe.

  15. Time irreversibility and intrinsics revealing of series with complex network approach

    Science.gov (United States)

    Xiong, Hui; Shang, Pengjian; Xia, Jianan; Wang, Jing

    2018-06-01

    In this work, we analyze time series on the basis of the visibility graph algorithm that maps the original series into a graph. By taking into account the all-round information carried by the signals, the time irreversibility and fractal behavior of series are evaluated from a complex network perspective, and considered signals are further classified from different aspects. The reliability of the proposed analysis is supported by numerical simulations on synthesized uncorrelated random noise, short-term correlated chaotic systems and long-term correlated fractal processes, and by the empirical analysis on daily closing prices of eleven worldwide stock indices. Obtained results suggest that finite size has a significant effect on the evaluation, and that there might be no direct relation between the time irreversibility and long-range correlation of series. Similarity and dissimilarity between stock indices are also indicated from respective regional and global perspectives, showing the existence of multiple features of underlying systems.

  16. The intensity detection of single-photon detectors based on photon counting probability density statistics

    International Nuclear Information System (INIS)

    Zhang Zijing; Song Jie; Zhao Yuan; Wu Long

    2017-01-01

    Single-photon detectors possess the ultra-high sensitivity, but they cannot directly respond to signal intensity. Conventional methods adopt sampling gates with fixed width and count the triggered number of sampling gates, which is capable of obtaining photon counting probability to estimate the echo signal intensity. In this paper, we not only count the number of triggered sampling gates, but also record the triggered time position of photon counting pulses. The photon counting probability density distribution is obtained through the statistics of a series of the triggered time positions. Then Minimum Variance Unbiased Estimation (MVUE) method is used to estimate the echo signal intensity. Compared with conventional methods, this method can improve the estimation accuracy of echo signal intensity due to the acquisition of more detected information. Finally, a proof-of-principle laboratory system is established. The estimation accuracy of echo signal intensity is discussed and a high accuracy intensity image is acquired under low-light level environments. (paper)

  17. Irreversible membrane fouling abatement through pre-deposited layer of hierarchical porous carbons

    KAUST Repository

    Hamad, Juma; Dua, Rubal; Kurniasari, Novita; Kennedy, Maria Dolores; Wang, Peng; Amy, Gary L.

    2014-01-01

    In this work, dual-templated hierarchical porous carbons (HPCs), produced from a coupled ice-hard templating approach, are shown to be a highly effective solution to the commonly occurring problem of irreversible fouling of low-pressure membranes

  18. Interplay of Determinism and Randomness: From Irreversibility to Chaos, Fractals, and Stochasticity

    Science.gov (United States)

    Tsonis, A.

    2017-12-01

    We will start our discussion into randomness by looking exclusively at our formal mathematical system to show that even in this pure and strictly logical system one cannot do away with randomness. By employing simple mathematical models, we will identify the three possible sources of randomness: randomness due to inability to find the rules (irreversibility), randomness due to inability to have infinite power (chaos), and randomness due to stochastic processes. Subsequently we will move from the mathematical system to our physical world to show that randomness, through the quantum mechanical character of small scales, through chaos, and because of the second law of thermodynamics, is an intrinsic property of nature as well. We will subsequently argue that the randomness in the physical world is consistent with the three sources of randomness suggested from the study of simple mathematical systems. Many examples ranging from purely mathematical to natural processes will be presented, which clearly demonstrate how the combination of rules and randomness produces the world we live in. Finally, the principle of least effort or the principle of minimum energy consumption will be suggested as the underlying principle behind this symbiosis between determinism and randomness.

  19. Anomalies, Unitarity and Quantum Irreversibility

    CERN Document Server

    Anselmi, D

    1999-01-01

    The trace anomaly in external gravity is the sum of three terms at criticality: the square of the Weyl tensor, the Euler density and Box R, with coefficients, properly normalized, called c, a and a', the latter being ambiguously defined by an additive constant. Unitarity and positivity properties of the induced actions allow us to show that the total RG flows of a and a' are equal and therefore the a'-ambiguity can be consistently removed through the identification a'=a. The picture that emerges clarifies several long-standing issues. The interplay between unitarity and renormalization implies that the flux of the renormalization group is irreversible. A monotonically decreasing a-function interpolating between the appropriate values is naturally provided by a'. The total a-flow is expressed non-perturbatively as the invariant (i.e. scheme-independent) area of the graph of the beta function between the fixed points. We test this prediction to the fourth loop order in perturbation theory, in QCD with Nf ~< ...

  20. Irreversible pulpitis and achieving profound anesthesia: Complexities and managements

    OpenAIRE

    Modaresi, Jalil; Davoudi, Amin; Badrian, Hamid; Sabzian, Roya

    2016-01-01

    Dental pain management is one of the most critical aspects of modern dentistry. Irreversible pulpitis and further root canal therapy might cause an untolerated pain to the patients. The improvements in anesthetic agents and techniques were one of the advantages of studying nerve biology and stimulation. This article tried to overview of the nerve activities in inflammatory environments or induced pain. Furthermore, the proper advises, and supplementary techniques were reviewed for better pain...

  1. Irreversibility and multiplicity: two criteria for the disposal of nuclear wastes

    International Nuclear Information System (INIS)

    Rochlin, G.

    1976-01-01

    Two criteria are suggested for comparing waste management methods: technical irreversibility and site multiplicity. These criteria can be used to reduce future risk in the face of inherent uncertainty and to provide for safe disposal without requiring guaranteed future ability to recognize, detect or repair areas of failure

  2. Repeatability of differential goat bulk milk culture and associations with somatic cell count, total bacterial count, and standard plate count

    NARCIS (Netherlands)

    Koop, G.; Dik, N.; Nielen, M.; Lipman, L.J.A.

    2010-01-01

    The aims of this study were to assess how different bacterial groups in bulk milk are related to bulk milk somatic cell count (SCC), bulk milk total bacterial count (TBC), and bulk milk standard plate count (SPC) and to measure the repeatability of bulk milk culturing. On 53 Dutch dairy goat farms,

  3. Exactly solvable irreversible processes on one-dimensional lattices

    International Nuclear Information System (INIS)

    Wolf, N.O.; Evans, J.W.; Hoffman, D.K.

    1984-01-01

    We consider the kinetics of a process where the sites of an infinite 1-D lattice are filled irreversibly and, in general, cooperatively by N-mers (taking N consecutive sites at a time). We extend the previously available exact solution for nearest neighbor cooperative effects to range N cooperative effects. Connection with the continuous ''cooperative car parking problem'' is indicated. Both uniform and periodic lattices, and empty and certain partially filled lattice initial conditions are considered. We also treat monomer ''filling in stages'' for certain highly autoinhibitory cooperative effects of arbitrary range

  4. Standardization of {sup 241}Am by digital coincidence counting, liquid scintillation counting and defined solid angle counting

    Energy Technology Data Exchange (ETDEWEB)

    Balpardo, C., E-mail: balpardo@cae.cnea.gov.a [Laboratorio de Metrologia de Radioisotopos, CNEA, Buenos Aires (Argentina); Capoulat, M.E.; Rodrigues, D.; Arenillas, P. [Laboratorio de Metrologia de Radioisotopos, CNEA, Buenos Aires (Argentina)

    2010-07-15

    The nuclide {sup 241}Am decays by alpha emission to {sup 237}Np. Most of the decays (84.6%) populate the excited level of {sup 237}Np with energy of 59.54 keV. Digital coincidence counting was applied to standardize a solution of {sup 241}Am by alpha-gamma coincidence counting with efficiency extrapolation. Electronic discrimination was implemented with a pressurized proportional counter and the results were compared with two other independent techniques: Liquid scintillation counting using the logical sum of double coincidences in a TDCR array and defined solid angle counting taking into account activity inhomogeneity in the active deposit. The results show consistency between the three methods within a limit of a 0.3%. An ampoule of this solution will be sent to the International Reference System (SIR) during 2009. Uncertainties were analysed and compared in detail for the three applied methods.

  5. Origin of the irreversibility line in thin YBa2Cu3O7-δ films with and without columnar defects

    International Nuclear Information System (INIS)

    Prozorov, R.; Konczykowski, M.; Schmidt, B.; Yeshurun, Y.; Shaulov, A.; Villard, C.; Koren, G.

    1996-01-01

    We report on measurements of the angular dependence of the irreversibility temperature T irr (θ) in YBa 2 Cu 3 O 7-δ thin films, defined by the onset of a third-harmonic signal and measured by a miniature Hall probe. From the functional form of T irr (θ) we conclude that the origin of the irreversibility line in unirradiated films is a dynamic crossover from an unpinned to a pinned vortex liquid. In irradiated films the irreversibility temperature is determined by the trapping angle. copyright 1996 The American Physical Society

  6. Irreversible colloidal agglomeration in presence of associative inhibitors: Computer simulation study

    International Nuclear Information System (INIS)

    Barcenas, Mariana; Duda, Yurko

    2007-01-01

    Monte Carlo simulation is employed to study the irreversible particle-cluster agglomeration of valence-limited colloids affected by associative inhibitors. The cluster size distribution and number of connections between colloids are analyzed as a function of density and inhibitor concentration. The influence of colloid functionality on its aggregation is discussed

  7. Performance assessment and optimization of an irreversible nano-scale Stirling engine cycle operating with Maxwell-Boltzmann gas

    Science.gov (United States)

    Ahmadi, Mohammad H.; Ahmadi, Mohammad-Ali; Pourfayaz, Fathollah

    2015-09-01

    Developing new technologies like nano-technology improves the performance of the energy industries. Consequently, emerging new groups of thermal cycles in nano-scale can revolutionize the energy systems' future. This paper presents a thermo-dynamical study of a nano-scale irreversible Stirling engine cycle with the aim of optimizing the performance of the Stirling engine cycle. In the Stirling engine cycle the working fluid is an Ideal Maxwell-Boltzmann gas. Moreover, two different strategies are proposed for a multi-objective optimization issue, and the outcomes of each strategy are evaluated separately. The first strategy is proposed to maximize the ecological coefficient of performance (ECOP), the dimensionless ecological function (ecf) and the dimensionless thermo-economic objective function ( F . Furthermore, the second strategy is suggested to maximize the thermal efficiency ( η), the dimensionless ecological function (ecf) and the dimensionless thermo-economic objective function ( F). All the strategies in the present work are executed via a multi-objective evolutionary algorithms based on NSGA∥ method. Finally, to achieve the final answer in each strategy, three well-known decision makers are executed. Lastly, deviations of the outcomes gained in each strategy and each decision maker are evaluated separately.

  8. Coupled Reversible and Irreversible Bistable Switches Underlying TGFβ-induced Epithelial to Mesenchymal Transition

    Science.gov (United States)

    Tian, Xiao-Jun; Zhang, Hang; Xing, Jianhua

    2013-01-01

    Epithelial to mesenchymal transition (EMT) plays an important role in embryonic development, tissue regeneration, and cancer metastasis. Whereas several feedback loops have been shown to regulate EMT, it remains elusive how they coordinately modulate EMT response to TGF-β treatment. We construct a mathematical model for the core regulatory network controlling TGF-β-induced EMT. Through deterministic analyses and stochastic simulations, we show that EMT is a sequential two-step program in which an epithelial cell first is converted to partial EMT then to the mesenchymal state, depending on the strength and duration of TGF-β stimulation. Mechanistically the system is governed by coupled reversible and irreversible bistable switches. The SNAIL1/miR-34 double-negative feedback loop is responsible for the reversible switch and regulates the initiation of EMT, whereas the ZEB/miR-200 feedback loop is accountable for the irreversible switch and controls the establishment of the mesenchymal state. Furthermore, an autocrine TGF-β/miR-200 feedback loop makes the second switch irreversible, modulating the maintenance of EMT. Such coupled bistable switches are robust to parameter variation and molecular noise. We provide a mechanistic explanation on multiple experimental observations. The model makes several explicit predictions on hysteretic dynamic behaviors, system response to pulsed stimulation, and various perturbations, which can be straightforwardly tested. PMID:23972859

  9. Model of the Evolution of Deformation Defects and Irreversible Strain at Thermal Cycling of Stressed TiNi Alloy Specimen

    Directory of Open Access Journals (Sweden)

    Volkov Aleksandr E.

    2015-01-01

    Full Text Available This microstructural model deals with simulation both of the reversible and irreversible deformation of a shape memory alloy (SMA. The martensitic transformation and the irreversible deformation due to the plastic accommodation of martensite are considered on the microscopic level. The irreversible deformation is described from the standpoint of the plastic flow theory. Isotropic hardening and kinematic hardening are taken into account and are related to the densities of scattered and oriented deformation defects. It is supposed that the phase transformation and the micro plastic deformation are caused by the generalized thermodynamic forces, which are the derivatives of the Gibbs’ potential of the two-phase body. In terms of these forces conditions for the phase transformation and for the micro plastic deformation on the micro level are formulated. The macro deformation of the representative volume of the polycrystal is calculated by averaging of the micro strains related to the evolution of the martensite Bain’s variants in each grain comprising this volume. The proposed model allowed simulating the evolution of the reversible and of the irreversible strains of a stressed SMA specimen under thermal cycles. The results show a good qualitative agreement with available experimental data. Specifically, it is shown that the model can describe a rather big irreversible strain in the first thermocycle and its fast decrease with the number of cycles.

  10. Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells

    OpenAIRE

    Soichiro Sonoda; Haruyoshi Yamaza; Lan Ma; Yosuke Tanaka; Erika Tomoda; Reona Aijima; Kazuaki Nonaka; Toshio Kukita; Songtao Shi; Fusanori Nishimura; Takayoshi Yamaza

    2016-01-01

    Clinically, irreversible pulpitis is treated by the complete removal of pulp tissue followed by replacement with artificial materials. There is considered to be a high potential for autologous transplantation of human dental pulp stem cells (DPSCs) in endodontic treatment. The usefulness of DPSCs isolated from healthy teeth is limited. However, DPSCs isolated from diseased teeth with irreversible pulpitis (IP-DPSCs) are considered to be suitable for dentin/pulp regeneration. In this study, we...

  11. Irreversibility in physics stemming from unpredictable symbol-handling agents

    Science.gov (United States)

    Myers, John M.; Madjid, F. Hadi

    2016-05-01

    The basic equations of physics involve a time variable t and are invariant under the transformation t --> -t. This invariance at first sight appears to impose time reversibility as a principle of physics, in conflict with thermodynamics. But equations written on the blackboard are not the whole story in physics. In prior work we sharpened a distinction obscured in today's theoretical physics, the distinction between obtaining evidence from experiments on the laboratory bench and explaining that evidence in mathematical symbols on the blackboard. The sharp distinction rests on a proof within the mathematics of quantum theory that no amount of evidence, represented in quantum theory in terms of probabilities, can uniquely determine its explanation in terms of wave functions and linear operators. Building on the proof we show here a role in physics for unpredictable symbol-handling agents acting both at the blackboard and at the workbench, communicating back and forth by means of transmitted symbols. Because of their unpredictability, symbol-handling agents introduce a heretofore overlooked source of irreversibility into physics, even when the equations they write on the blackboard are invariant under t --> -t. Widening the scope of descriptions admissible to physics to include the agents and the symbols that link theory to experiments opens up a new source of time-irreversibility in physics.

  12. Clean Hands Count

    Medline Plus

    Full Text Available ... Like this video? Sign in to make your opinion count. Sign in 131 2 Don't like this video? Sign in to make your opinion count. Sign in 3 Loading... Loading... Transcript The ...

  13. Optimization of simultaneous tritium–radiocarbon internal gas proportional counting

    Energy Technology Data Exchange (ETDEWEB)

    Bonicalzi, R.M. [Seattle Central College, 1701 Broadway, Seattle, WA 98122 (United States); Aalseth, C.E.; Day, A.R.; Hoppe, E.W. [Pacific Northwest National Laboratory, 902 Battelle Boulevard, Richland, WA 99352 (United States); Mace, E.K., E-mail: Emily.Mace@pnl.gov [Pacific Northwest National Laboratory, 902 Battelle Boulevard, Richland, WA 99352 (United States); Moran, J.J.; Overman, C.T.; Panisko, M.E.; Seifert, A. [Pacific Northwest National Laboratory, 902 Battelle Boulevard, Richland, WA 99352 (United States)

    2016-03-21

    Specific environmental applications can benefit from dual tritium and radiocarbon measurements in a single compound. Assuming typical environmental levels, it is often the low tritium activity relative to the higher radiocarbon activity that limits the dual measurement. In this paper, we explore the parameter space for a combined tritium and radiocarbon measurement using a natural methane sample mixed with an argon fill gas in low-background proportional counters of a specific design. We present an optimized methane percentage, detector fill pressure, and analysis energy windows to maximize measurement sensitivity while minimizing count time. The final optimized method uses a 9-atm fill of P35 (35% methane, 65% argon), and a tritium analysis window from 1.5 to 10.3 keV, which stops short of the tritium beta decay endpoint energy of 18.6 keV. This method optimizes tritium-counting efficiency while minimizing radiocarbon beta-decay interference. - Highlights: • Use of a single compound (methane) for dual tritium and radiocarbon measurements. • Optimized analysis window for simultaneous tritium and radiocarbon measurement. • Allows for optimization of tritium counting in the presence of radiocarbon.

  14. Entransy analysis of irreversible heat pump using Newton and Dulong–Petit heat transfer laws and relations with its performance

    International Nuclear Information System (INIS)

    Açıkkalp, Emin

    2014-01-01

    Highlights: • Entransy analysis was made for irreversible heat pump. • Newton and Dulong–Petit heat transfer laws were used. • Entransy dissipations were defined and determined. • Relations between entransy and other thermodynamic parameters were determined. - Abstract: An irreversible heat pump was investigated via entransy analysis and performance criteria. In the analyses, two different convective heat transfer laws were applied to the considered system: the Newton and Dulong–Petit heat transfer laws. The irreversibilities in the system are the result of a finite heat transfer rate, a heat leak and internal irreversibilities, including friction, turbulence etc. In this study, a thermodynamic analysis was performed in detail, and the numerical solutions were used for the conducted analysis. The maximum entransy dissipation (critical points) ranges from 18436.7 kW K to 18855.3 kW K according to y for Newton’s law; however, there is no maximum point for the Dulon–Petit law. It can be concluded from this study that entransy should be used among the basic thermodynamic criteria

  15. Clean Hands Count

    Medline Plus

    Full Text Available ... starting stop Loading... Watch Queue Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with ... ads? Get YouTube Red. Working... Not now Try it free Find out why Close Clean Hands Count ...

  16. La asistencia al final de la vida: la ortotanasia

    OpenAIRE

    Gamarra, Maria del Pilar

    2011-01-01

    La muerte es un hecho natural e inevitable, que pone fin a la vida. En un sistema sanitario construido sobre el modelo de la terapia curativa, los profesionales de la salud han sido formados y han desarrollado su actividad como si el proceso de la muerte no existiera.Muchos profesionales no tienen incorporada la actuación en el abordaje del paciente en el final de su vida, cómo comunicar la verdad de la situación irreversible, los tratamientos paliativos y el apoyo emocional al paciente y a s...

  17. New method for evaluating irreversible adsorption and stationary phase bleed in gas chromatographic capillary columns.

    Science.gov (United States)

    Wright, Bob W; Wright, Cherylyn W

    2012-10-26

    A novel method is described for the evaluation of irreversible adsorption and column bleed in gas chromatographic (GC) columns using a tandem GC approach. This work specifically determined the degree of irreversible adsorption behavior of specific sulfur and phosphorous containing test probe compounds at levels ranging from approximately 50 picograms (pg) to 1 nanogram (ng) on selected gas chromatographic columns. This method does not replace existing evaluation methods that characterize reversible adsorption but provides an additional tool. The test compounds were selected due to their ease of adsorption and their importance in the specific trace analytical detection methodology being developed. Replicate chromatographic columns with 5% phenylmethylpolysiloxane (PMS), polyethylene glycol (wax), trifluoropropylpolysiloxane (TFP), or 78% cyanopropylpolysiloxane stationary phases from a variety of vendors were evaluated. As expected, the results demonstrate that the different chromatographic phases exhibit differing degrees of irreversible adsorption behavior. The results also indicate that all manufacturers do not produce equally inert columns nor are columns from a given manufacturer identical. The wax-coated columns for the test probes used were more inert as a group than 5% PMS coated columns, and they were more reproducibly manufactured. Both TFP and 78% cyanopropylpolysiloxane columns displayed superior inertness to the test compounds compared to either 5% PMS- or wax-coated columns. Irreversible adsorption behavior was characterized for a limited range of stationary phase film thicknesses. In addition, the method was shown effective for characterizing column bleed and methods to remove bleed components. This method is useful in screening columns for demanding applications and to obtain diagnostic information related to improved preparation methods. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Thermodynamic restrictions on linear reversible and irreversible thermo-electro-magneto-mechanical processes

    Directory of Open Access Journals (Sweden)

    Sushma Santapuri

    2016-10-01

    Full Text Available A unified thermodynamic framework for the characterization of functional materials is developed. This framework encompasses linear reversible and irreversible processes with thermal, electrical, magnetic, and/or mechanical effects coupled. The comprehensive framework combines the principles of classical equilibrium and non-equilibrium thermodynamics with electrodynamics of continua in the infinitesimal strain regime.In the first part of this paper, linear Thermo-Electro-Magneto-Mechanical (TEMM quasistatic processes are characterized. Thermodynamic stability conditions are further imposed on the linear constitutive model and restrictions on the corresponding material constants are derived. The framework is then extended to irreversible transport phenomena including thermoelectric, thermomagnetic and the state-of-the-art spintronic and spin caloritronic effects. Using Onsager's reciprocity relationships and the dissipation inequality, restrictions on the kinetic coefficients corresponding to charge, heat and spin transport processes are derived. All the constitutive models are accompanied by multiphysics interaction diagrams that highlight the various processes that can be characterized using this framework. Keywords: Applied mathematics, Materials science, Thermodynamics

  19. Thermal mechanisms responsible for the irreversible degradation of superconductivity in commercial superconductors

    Science.gov (United States)

    Romanovskii, V. R.

    2017-08-01

    Conditions for the irreversible propagation of thermal instabilities in commercial superconductors subjected to intense and soft cooling have been formulated. An analysis has been conducted using two types of the superconductor's I-V characteristics, i.e., an ideal I-V characteristic, which assumes a step superconducting-to-normal transition, and a continuous I-V characteristic, which is described by a power law. The propagation rate of thermal instabilities along the superconducting composite has been determined. Calculations have been made for both subcritical and supercritical values of the current. It has been shown that they propagate along a commercial superconductor in the form of a switching wave. In rapidly cooled commercial superconductors, the steady-state rate of thermal instability propagation in the longitudinal direction can only be positive because there is no region of steady stabilization. It has been proved that, in the case of thermal instability irreversible propagation, the rise in the commercial superconductor temperature is similar to diffusion processes that occur in explosive chain reactions.

  20. Beta-lactam antibiotic-induced platelet dysfunction: Evidence for irreversible inhibition of platelet activation in vitro and in vivo after prolonged exposure to penicillin

    International Nuclear Information System (INIS)

    Burroughs, S.F.; Johnson, G.J.

    1990-01-01

    beta-Lactam antibiotics cause platelet dysfunction with bleeding complications. Previous in vitro studies documented reversible inhibition of agonist-receptor interaction. This mechanism is inadequate to explain the effect of beta-lactam antibiotics in vivo. Platelet function does not return to normal immediately after drug treatment, implying irreversible inhibition of platelet function. We report here evidence of irreversible platelet functional and biochemical abnormalities after in vitro and in vivo exposure to beta-lactam antibiotics. Irreversible binding of [14C]-penicillin (Pen) occurred in vitro. After 24 hours' in vitro incubation with 10 to 20 mmol/L Pen, or ex vivo after antibiotic treatment, irreversible functional impairment occurred; but no irreversible inhibition of alpha 2 adrenergic receptors, measured with [3H]-yohimbine, or high-affinity thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptors, measured with agonist [3H]-U46619 and antagonist [3H]-SQ29548, occurred. However, low-affinity platelet TXA2/PGH2 receptors were decreased 40% after Pen exposure in vitro or in vivo, indicating irreversible membrane alteration. Two postreceptor biochemical events were irreversibly inhibited in platelets incubated with Pen for 24 hours in vitro or ex vivo after antibiotic treatment. Thromboxane synthesis was inhibited 28.3% to 81.7%. Agonist-induced rises in cytosolic calcium ([Ca2+]i) were inhibited 40.1% to 67.5% in vitro and 26.6% to 52.2% ex vivo. Therefore, Pen binds to platelets after prolonged exposure, resulting in irreversible dysfunction attributable to inhibition of TXA2 synthesis and impairment of the rise in [Ca2+]i. The loss of low-affinity TXA2/PGH2 receptors suggests that the primary site of action of these drugs is on the platelet membrane

  1. Effect of preoperative alprazolam on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.

    Science.gov (United States)

    Khademi, Abbas Ali; Saatchi, Masoud; Minaiyan, Mohsen; Rostamizadeh, Nasim; Sharafi, Fatemeh

    2012-10-01

    Success of inferior alveolar nerve (IAN) block decreases in patients with irreversible pulpitis. The purpose of this study was to evaluate the effect of preoperative administration of alprazolam on the success of the IAN block for teeth with irreversible pulpitis. Sixty patients with irreversible pulpitis of a mandibular molar were selected for this prospective, randomized, double-blind, placebo-controlled study. The patients received identical capsules of either 0.5 mg of alprazolam or placebo 45 minutes before the administration of a conventional IAN block. Access cavity preparation was initiated 15 minutes after the IAN block injection. Lip numbness was recorded for all the patients. Success was defined as no or mild pain on the basis of visual analogue scale recordings during access cavity preparation and initial instrumentation. Data were analyzed by t test, Mann-Whitney, and χ(2) tests. The success rate was 53% for alprazolam group and 40% for placebo group, with no significant difference between the 2 groups (P = .301). Within the scope of the current study, preoperative oral administration of 0.5 mg of alprazolam did not improve the success of the IAN block in mandibular molars in patients with irreversible pulpitis, and the success rate was not adequate to ensure profound pulpal anesthesia. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  2. Count-to-count time interval distribution analysis in a fast reactor

    International Nuclear Information System (INIS)

    Perez-Navarro Gomez, A.

    1973-01-01

    The most important kinetic parameters have been measured at the zero power fast reactor CORAL-I by means of the reactor noise analysis in the time domain, using measurements of the count-to-count time intervals. (Author) 69 refs

  3. Antibiotics are not useful to reduce pain associated with irreversible pulpitis.

    Science.gov (United States)

    Hoskin, Eileen; Veitz-Keenan, Analia

    2016-09-01

    Data sourcesCochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, Clinical Trials.gov and the WHO International Clinical Trials Registry Platform. There were no language restrictions.Study selectionRandomised controlled trials which compared the relief of pain with systemic antibiotics and analgesics against placebo and analgesics in the preoperative phase of irreversible pulpitis. The primary interest was pain control with an antibiotic or without one in the presence of analgesics. The secondary outcomes were type, dose and frequency of medication for pain relief and any adverse effects related to hypersensitivity or other reactions to either the antibiotic or analgesics.Data extraction and synthesisTwo authors independently assessed the results of the searches. Data extraction and risk bias assessment were also carried out independently. A third reviewer settled any disagreement on inclusion. Since only one study was included a meta-analysis could not be performed.ResultsOnly one double blind randomised clinical trial involving 40 participants with a diagnosis of irreversible pulpitis in one of their teeth was included in this review. This was a low risk, well-constructed double blind study. Half of the participants were treated with penicillin 500 mg, the other with a placebo every six hours over a seven- day period. In addition, all the participants were instructed to initially take one tablet of ibuprofen every 4-6 hours as needed and to take acetaminophen with codeine (two tablets every 4-6 hours) only if the ibuprofen did not relieve the pain.There was no significant difference in the mean total number of ibuprofen tablets over the study period; 9.2(standard deviation (SD) 6.02) in the penicillin group versus, 9.6 (SD 6.34) in the placebo group; mean difference -0.40 (95% CI -4.23 to 3.43); P value = 0.84.The mean total number of Tylenol tablets, 6.9 (SD 6.87), used in the penicillin group versus 4

  4. Irreversibility in room temperature current–voltage characteristics of NiFe{sub 2}O{sub 4} nanoparticles: A signature of electrical memory effect

    Energy Technology Data Exchange (ETDEWEB)

    Dey, P., E-mail: pujaiitkgp2007@gmail.com [Department of Physics, Kazi Nazrul University, Asansol, W.B. 713340 (India); Debnath, Rajesh; Singh, Swati; Mandal, S.K. [Department of Physics, National Institute of Technology Agartala, Tripura 799046 (India); Roy, J.N. [Department of Physics, Kazi Nazrul University, Asansol, W.B. 713340 (India); Department of Physics, National Institute of Technology Agartala, Tripura 799046 (India)

    2017-01-01

    Room temperature I–V characteristics study, both in presence and absence of magnetic field (1800 Oe), has been performed on NiFe{sub 2}O{sub 4} nanoparticles, having different particle size (φ~14, 21 and 31 nm). Our experiments on these nanoparticles provide evidences for: (1) electrical irreversibility or hysteretic behaviour; (2) positive magnetoresistance and (3) magnetic field dependent electrical irreversibility or hysteresis in the sample. “Hysteretic” nature of I–V curve reveals the existence of electrical memory effect in the sample. Significantly, such hysteresis has been found to be tuned by magnetic field. In order to explain the observed electrical irreversibility, we have proposed a phenomenological model on the light of induced polarization in the sample. Both the positive magnetoresistance and the observed magnetic field dependence of electrical irreversibility have been explained through magnetostriction phenomenon. Interestingly, such effects are found to get reduced with increasing particle size. For NiFe{sub 2}O{sub 4} nanoparticles having φ=31 nm, we did not observe any irreversibility effect. This feature has been attributed to the enhanced grain surface effect that in turn gives rise to the residual polarization and hence electrical memory effect in NiFe{sub 2}O{sub 4} nanoparticles, having small nanoscopic particle size. - Highlights: • I-V characteristics study of NiFe{sub 2}O{sub 4} nanoparticles with varying particle sizes. • Experiments evident electrical hysteretic behaviour, i.e., electrical memory effect. • Magnetic field dependent electrical irreversibility is due to magnetostriction. • A phenomenological model has been proposed on the light of induced polarization. • Such electrical irreversibility decreases with increasing particle sizes.

  5. Electrochemical characterization of irreversibly adsorbed germanium on platinum stepped surfaces vicinal to Pt(1 0 0)

    International Nuclear Information System (INIS)

    Rodriguez, P.; Herrero, E.; Solla-Gullon, J.; Vidal-Iglesias, F.J.; Aldaz, A.; Feliu, J.M.

    2005-01-01

    The electrochemical behavior of germanium irreversibly adsorbed at stepped surfaces vicinal to the Pt(1 0 0) pole is reported. The process taking part on the (1 0 0) terraces is evaluated from charge density measurements and calibration lines versus the terrace dimension are plotted. On the series Pt(2n - 1,1,1) having (1 1 1) monoatomic steps, the charge involved in the redox process undergone by the irreversibly adsorbed germanium is able to account for (n - 0.5) terrace atoms, thus suggesting some steric difficulties in the growth of the adlayer on the (1 0 0) terraces. Conversely, no steric problems are apparent in the series Pt(n,1,0) in which more open (1 0 0) steps are present on the (1 0 0) terraces. In this latter case the charge density under the germanium redox peaks is proportional to the number of terrace atoms. Some comparison is made with other stepped surfaces to understand the behavior and stability of germanium irreversibly adsorbed on the different platinum surface sites

  6. Colour quenching corrections on the measurement of 90Sr through Cerenkov counting

    International Nuclear Information System (INIS)

    Mosqueda, F.; Villa, M.; Vaca, F.; Bolivar, J.P.

    2007-01-01

    The determination of 90 Sr through the Cerenkov radiation emitted by its descendant 90 Y is a well-known method and firmly established in literature. Nevertheless, in order to obtain an accurate result based on a Cerenkov measurement, the experimental work must be extremely rigorous because the efficiency of Cerenkov counting is especially sensitive to the presence of colour. Any traces of colour in the sample produce a decrease in the number of photons detected in the photomultipliers and, therefore, this might cause a diminution in Cerenkov counting efficiency. It is essential not only to detect the effect of colour quenching in the sample but also to correct the decrease in counting efficiency. For this reason, colour quenching correction curves versus counting efficiency are usually done when measuring through Cerenkov counting. One of the most widely used techniques to evaluate colour quenching in these measurements is the channel ratio method, which consists of the measurement of the shift of the spectrum measuring the ratio of counts in two different windows. The selection of the windows for the application of the corrections might have an influence on the quality of the fitting parameters of the correction curves efficiency versus colour quenching degree and hence on the final 90 Sr result. This work is focused on the calculation of the counting efficiency decrease using the channel ratio method and on obtaining the best fitting correction curve. For this purpose, empirical curves obtained through artificial quenchers have been studied and the results have been tested in real samples. Additionally, given that the Packard Tri-Carb 3170 TR/SL liquid scintillation counter is a novel detector for use in Cerenkov counting, the previous calibration of the Tri-Carb 3170 TR/SL detector, necessary for the measurement of 90 Sr, is included

  7. Maximum entropy deconvolution of low count nuclear medicine images

    International Nuclear Information System (INIS)

    McGrath, D.M.

    1998-12-01

    Maximum entropy is applied to the problem of deconvolving nuclear medicine images, with special consideration for very low count data. The physics of the formation of scintigraphic images is described, illustrating the phenomena which degrade planar estimates of the tracer distribution. Various techniques which are used to restore these images are reviewed, outlining the relative merits of each. The development and theoretical justification of maximum entropy as an image processing technique is discussed. Maximum entropy is then applied to the problem of planar deconvolution, highlighting the question of the choice of error parameters for low count data. A novel iterative version of the algorithm is suggested which allows the errors to be estimated from the predicted Poisson mean values. This method is shown to produce the exact results predicted by combining Poisson statistics and a Bayesian interpretation of the maximum entropy approach. A facility for total count preservation has also been incorporated, leading to improved quantification. In order to evaluate this iterative maximum entropy technique, two comparable methods, Wiener filtering and a novel Bayesian maximum likelihood expectation maximisation technique, were implemented. The comparison of results obtained indicated that this maximum entropy approach may produce equivalent or better measures of image quality than the compared methods, depending upon the accuracy of the system model used. The novel Bayesian maximum likelihood expectation maximisation technique was shown to be preferable over many existing maximum a posteriori methods due to its simplicity of implementation. A single parameter is required to define the Bayesian prior, which suppresses noise in the solution and may reduce the processing time substantially. Finally, maximum entropy deconvolution was applied as a pre-processing step in single photon emission computed tomography reconstruction of low count data. Higher contrast results were

  8. Optimization of simultaneous tritium–radiocarbon internal gas proportional counting

    Energy Technology Data Exchange (ETDEWEB)

    Bonicalzi, R. M.; Aalseth, C. E.; Day, A. R.; Hoppe, E. W.; Mace, E. K.; Moran, J. J.; Overman, C. T.; Panisko, M. E.; Seifert, A.

    2016-03-01

    Specific environmental applications can benefit from dual tritium and radiocarbon measurements in a single compound. Assuming typical environmental levels, it is often the low tritium activity relative to the higher radiocarbon activity that limits the dual measurement. In this paper, we explore the parameter space for a combined tritium and radiocarbon measurement using a methane sample mixed with an argon fill gas in low-background proportional counters of a specific design. We present an optimized methane percentage, detector fill pressure, and analysis energy windows to maximize measurement sensitivity while minimizing count time. The final optimized method uses a 9-atm fill of P35 (35% methane, 65% argon), and a tritium analysis window from 1.5 to 10.3 keV, which stops short of the tritium beta decay endpoint energy of 18.6 keV. This method optimizes tritium counting efficiency while minimizing radiocarbon beta decay interference.

  9. The effect of volume and quenching on estimation of counting efficiencies in liquid scintillation counting

    International Nuclear Information System (INIS)

    Knoche, H.W.; Parkhurst, A.M.; Tam, S.W.

    1979-01-01

    The effect of volume on the liquid scintillation counting performance of 14 C-samples has been investigated. A decrease in counting efficiency was observed for samples with volumes below about 6 ml and those above about 18 ml when unquenched samples were assayed. Two quench-correction methods, sample channels ratio and external standard channels ratio, and three different liquid scintillation counters, were used in an investigation to determine the magnitude of the error in predicting counting efficiencies when small volume samples (2 ml) with different levels of quenching were assayed. The 2 ml samples exhibited slightly greater standard deviations of the difference between predicted and determined counting efficiencies than did 15 ml samples. Nevertheless, the magnitude of the errors indicate that if the sample channels ratio method of quench correction is employed, 2 ml samples may be counted in conventional counting vials with little loss in counting precision. (author)

  10. TasselNet: counting maize tassels in the wild via local counts regression network.

    Science.gov (United States)

    Lu, Hao; Cao, Zhiguo; Xiao, Yang; Zhuang, Bohan; Shen, Chunhua

    2017-01-01

    Accurately counting maize tassels is important for monitoring the growth status of maize plants. This tedious task, however, is still mainly done by manual efforts. In the context of modern plant phenotyping, automating this task is required to meet the need of large-scale analysis of genotype and phenotype. In recent years, computer vision technologies have experienced a significant breakthrough due to the emergence of large-scale datasets and increased computational resources. Naturally image-based approaches have also received much attention in plant-related studies. Yet a fact is that most image-based systems for plant phenotyping are deployed under controlled laboratory environment. When transferring the application scenario to unconstrained in-field conditions, intrinsic and extrinsic variations in the wild pose great challenges for accurate counting of maize tassels, which goes beyond the ability of conventional image processing techniques. This calls for further robust computer vision approaches to address in-field variations. This paper studies the in-field counting problem of maize tassels. To our knowledge, this is the first time that a plant-related counting problem is considered using computer vision technologies under unconstrained field-based environment. With 361 field images collected in four experimental fields across China between 2010 and 2015 and corresponding manually-labelled dotted annotations, a novel Maize Tassels Counting ( MTC ) dataset is created and will be released with this paper. To alleviate the in-field challenges, a deep convolutional neural network-based approach termed TasselNet is proposed. TasselNet can achieve good adaptability to in-field variations via modelling the local visual characteristics of field images and regressing the local counts of maize tassels. Extensive results on the MTC dataset demonstrate that TasselNet outperforms other state-of-the-art approaches by large margins and achieves the overall best counting

  11. TasselNet: counting maize tassels in the wild via local counts regression network

    Directory of Open Access Journals (Sweden)

    Hao Lu

    2017-11-01

    Full Text Available Abstract Background Accurately counting maize tassels is important for monitoring the growth status of maize plants. This tedious task, however, is still mainly done by manual efforts. In the context of modern plant phenotyping, automating this task is required to meet the need of large-scale analysis of genotype and phenotype. In recent years, computer vision technologies have experienced a significant breakthrough due to the emergence of large-scale datasets and increased computational resources. Naturally image-based approaches have also received much attention in plant-related studies. Yet a fact is that most image-based systems for plant phenotyping are deployed under controlled laboratory environment. When transferring the application scenario to unconstrained in-field conditions, intrinsic and extrinsic variations in the wild pose great challenges for accurate counting of maize tassels, which goes beyond the ability of conventional image processing techniques. This calls for further robust computer vision approaches to address in-field variations. Results This paper studies the in-field counting problem of maize tassels. To our knowledge, this is the first time that a plant-related counting problem is considered using computer vision technologies under unconstrained field-based environment. With 361 field images collected in four experimental fields across China between 2010 and 2015 and corresponding manually-labelled dotted annotations, a novel Maize Tassels Counting (MTC dataset is created and will be released with this paper. To alleviate the in-field challenges, a deep convolutional neural network-based approach termed TasselNet is proposed. TasselNet can achieve good adaptability to in-field variations via modelling the local visual characteristics of field images and regressing the local counts of maize tassels. Extensive results on the MTC dataset demonstrate that TasselNet outperforms other state-of-the-art approaches by large

  12. Effects of Point Count Duration, Time-of-Day, and Aural Stimuli on Detectability of Migratory and Resident Bird Species in Quintana Roo, Mexico

    Science.gov (United States)

    James F. Lynch

    1995-01-01

    Effects of count duration, time-of-day, and aural stimuli were studied in a series of unlimited-radius point counts conducted during winter in Quintana Roo, Mexico. The rate at which new species were detected was approximately three times higher during the first 5 minutes of each 15- minute count than in the final 5 minutes. The number of individuals and species...

  13. Isospectral discrete and quantum graphs with the same flip counts and nodal counts

    Science.gov (United States)

    Juul, Jonas S.; Joyner, Christopher H.

    2018-06-01

    The existence of non-isomorphic graphs which share the same Laplace spectrum (to be referred to as isospectral graphs) leads naturally to the following question: what additional information is required in order to resolve isospectral graphs? It was suggested by Band, Shapira and Smilansky that this might be achieved by either counting the number of nodal domains or the number of times the eigenfunctions change sign (the so-called flip count) (Band et al 2006 J. Phys. A: Math. Gen. 39 13999–4014 Band and Smilansky 2007 Eur. Phys. J. Spec. Top. 145 171–9). Recent examples of (discrete) isospectral graphs with the same flip count and nodal count have been constructed by Ammann by utilising Godsil–McKay switching (Ammann private communication). Here, we provide a simple alternative mechanism that produces systematic examples of both discrete and quantum isospectral graphs with the same flip and nodal counts.

  14. Thermomagnetic behaviour and compositional irreversibility on (Fe/Si)3 multilayer films

    International Nuclear Information System (INIS)

    Badía-Romano, L.; Rubín, J.; Magén, C.; Bartolomé, F.; Sesé, J.; Ibarra, M.R.; Bartolomé, J.

    2014-01-01

    This work presents the correlation between the morphology and magnetic properties of (Fe/Si) 3 multilayers with different Fe layer thicknesses and fixed Si spacer thickness in a broad temperature range (5 R /M S ratios and saturation fields are related to several types of interlayer exchange coupling. 90°-coupling and a superposition of 90° and antiferromagnetic interlayer exchange coupling are found depending on the Fe layer thickness. Magnetization curves were investigated as a function of temperature by in situ annealing. They show an irreversible thermal process as temperature increases from 300 to 450 K that is correlated to the formation of a ferromagnetic silicide phase. At higher temperature this phase transforms into a paramagnetic Fe–Si phase. - Highlights: • A thermomagnetic study on (Fe/Si) 3 multilayers is performed by in situ annealing. • We assess on the Fe layer thickness dependence, while the Si spacer is fixed. • 90° and AF interlayer exchange couplings are found depending on the Fe thickness. • We report an irreversible thermal process, correlated to chemical transformations. • The integrity of these (Fe/Si) 3 films is conserved just till T≈410K

  15. A Frank mixture copula family for modeling higher-order correlations of neural spike counts

    International Nuclear Information System (INIS)

    Onken, Arno; Obermayer, Klaus

    2009-01-01

    In order to evaluate the importance of higher-order correlations in neural spike count codes, flexible statistical models of dependent multivariate spike counts are required. Copula families, parametric multivariate distributions that represent dependencies, can be applied to construct such models. We introduce the Frank mixture family as a new copula family that has separate parameters for all pairwise and higher-order correlations. In contrast to the Farlie-Gumbel-Morgenstern copula family that shares this property, the Frank mixture copula can model strong correlations. We apply spike count models based on the Frank mixture copula to data generated by a network of leaky integrate-and-fire neurons and compare the goodness of fit to distributions based on the Farlie-Gumbel-Morgenstern family. Finally, we evaluate the importance of using proper single neuron spike count distributions on the Shannon information. We find notable deviations in the entropy that increase with decreasing firing rates. Moreover, we find that the Frank mixture family increases the log likelihood of the fit significantly compared to the Farlie-Gumbel-Morgenstern family. This shows that the Frank mixture copula is a useful tool to assess the importance of higher-order correlations in spike count codes.

  16. Which elements are involved in reversible and irreversible cartilage degradation in osteoarthritis?

    DEFF Research Database (Denmark)

    Bay-Jensen, Anne-Christine; Hoegh-Madsen, Suzi; Dam, Erik

    2010-01-01

    -physiology of the joint and whether the joint damage is reversible or irreversible. In this review, we compile emerging data on cellular and pathological aspects of OA, and ask whether these data could give clue to when cartilage degradation is reversible and whether a point-of-no-return exists. We highlight different...

  17. Counting It Twice.

    Science.gov (United States)

    Schattschneider, Doris

    1991-01-01

    Provided are examples from many domains of mathematics that illustrate the Fubini Principle in its discrete version: the value of a summation over a rectangular array is independent of the order of summation. Included are: counting using partitions as in proof by pictures, combinatorial arguments, indirect counting as in the inclusion-exclusion…

  18. Low White Blood Cell Count

    Science.gov (United States)

    Symptoms Low white blood cell count By Mayo Clinic Staff A low white blood cell count (leukopenia) is a decrease ... of white blood cell (neutrophil). The definition of low white blood cell count varies from one medical ...

  19. Incidence of missed inferior alveolar nerve blocks in vital asymptomatic subjects and in patients with symptomatic irreversible pulpitis.

    Science.gov (United States)

    Fowler, Sara; Reader, Al; Beck, Mike

    2015-05-01

    The purpose of this retrospective study was to determine the incidence of missed inferior alveolar nerve (IAN) blocks by using a 1- or 2-cartridge volume of 2% lidocaine with 1:100,000 epinephrine in vital asymptomatic teeth and in emergency patients with symptomatic irreversible pulpitis. As part of 37 studies, 3169 subjects/patients were evaluated for missed IAN blocks. The study included 2450 asymptomatic subjects and 719 emergency patients presenting with symptomatic irreversible pulpitis. Each subject or patient received either a 1- or 2-cartridge volume of 2% lidocaine with 1:100,000 epinephrine. A missed block was defined as no lip numbness at 15-20 minutes after the IAN block. The effect of anesthetic volume on the incidence of missed blocks was assessed by using mixed models logistic regression with individual studies as a random effect. The incidence of missed blocks for asymptomatic subjects was 6.3% for the 1-cartridge volume and 3.8% for the 2-cartridge volume. For patients presenting with irreversible pulpitis, the incidence of missed blocks was 7.7% for the 1-cartridge volume and 2.3% for the 2-cartridge volume. In both asymptomatic subjects and patients with irreversible pulpitis, the 2-cartridge volume was significantly (P = .0395) better than the 1-cartridge volume. There were no significant effects for pulpal diagnosis (P = .7523) or the pulpal diagnosis and anesthetic volume interaction (P = .3973). Concerning missed IAN blocks, we concluded that administration of a 2-cartridge volume was significantly better (P = .0395) than a 1-cartridge volume in both asymptomatic subjects and emergency patients presenting with irreversible pulpitis. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  20. Recognition of reversible and irreversible myocardial injury by technetium pyrophosphate extraction kinetics

    International Nuclear Information System (INIS)

    Silva, R.; Chen, Y.F.; Sell, T.L.; Lowe, J.E.; Jones, R.H.

    1987-01-01

    The need for a more accurate method of detecting episodes of myocardial ischemia during cardiac operations, particularly during the ischemic arrest interval, prompted us to investigate the usefulness of measuring the active extraction of technetium pyrophosphate in identifying and quantitating ischemic injury. Twenty-four adult mongrel dogs were subjected to cardiopulmonary bypass, and normothermic global ischemia was induced by cross-clamping the proximal aorta. Technetium pyrophosphate (1 mCi) was injected through a standard cardioplegia line with normal saline, simulating administration of cardioplegic solution, upon placement of the aortic cross-clamp (time 0), at 15, 30, 45, and 60 minutes of global ischemia, and with the onset and completion of ischemic contracture. Radioactive counts were recorded over the heart at 1 second intervals, and the extraction fraction and half-time of clearance were calculated. The extraction fraction increased from 0.22 at time 0 to 0.58 at 15 minutes, 0.82 at 30 minutes, 0.85 at 45 minutes, and 0.91 at 60 minutes. The halftime increased from a baseline of 114 seconds (time 0) to a maximum of 321 seconds at 60 minutes of ischemia. The onset and completion of ischemic contracture showed a return toward baseline of both the extraction fraction and halftime of clearance, with an extraction fraction of 0.44 and 0.46 and a halftime of 135 and 133 seconds, respectively. These data clearly show that reversible myocardial injury increased the extraction and reduced the clearance of technetium pyrophosphate and that the magnitude of change related to the extent of injury. The progression to irreversible myocardial injury decreased the active extraction of technetium pyrophosphate. This simple procedure for real-time documentation of myocardial injury promises to provide easily obtainable endpoints of injury for use during cardiac operations in humans

  1. Basic quantum irreversibility in neutron interferometry

    International Nuclear Information System (INIS)

    Rauch, H

    2009-01-01

    The transition between the quantum and classical world is a topical problem in quantum physics, which can be investigated by neutron interferometric methods. Here we discuss unavoidable quantum losses as they appear in neutron phase-echo and spin rotation experiments and we show how entanglement effects in a single-particle system demonstrate quantum contextuality, i.e. an entanglement between external and internal degrees of freedom in single-particle systems. This contextuality phenomenon also shows that a quantum system carries much more information than usually extracted. In all cases of an interaction, parasitic beams are produced which cannot be recombined completely with the original beam. This means that a complete reconstruction of the original state is, in principle, impossible which causes a kind of intrinsic irreversibility. Even small interaction potentials can have huge effects when they are applied in quantum Zeno-like experiments. The path towards advanced neutron quantum optics will be discussed.

  2. A relation between irreversibility and unlinkability for biometric template protection algorithms

    OpenAIRE

    井沼, 学

    2014-01-01

    For biometric recognition systems, privacy protection of enrolled users’ biometric information, which are called biometric templates, is a critical problem. Recently, various template protection algorithms have been proposed and many related previous works have discussed security notions to evaluate the protection performance of these protection algorithms. Irreversibility and unlinkability are important security notions discussed in many related previous works. In this paper, we prove that u...

  3. Competing irreversible cooperative reactions on polymer chains

    International Nuclear Information System (INIS)

    Evans, J.W.; Hoffman, D.K.; Burgess, D.R.

    1984-01-01

    We analyze model processes involving competition between several irreversible reactions at the sites of a 1D, infinite, uniform polymer chain. These reactions can be cooperative, i.e., the corresponding rates depend on the state of the surrounding sites. An infinite hierarchy of rate equations is readily derived for the probabilities of various subconfigurations. By exploiting a shielding property of suitable blocks of unreacted sites, we show how exact hierarchy truncation and solution is sometimes possible. The behavior of solutions is illustrated in several cases by plotting families of ''reaction trajectories'' for varying ratios of reactant concentrations. As a specific application, we consider competition between coordination of ZnCl 2 to pairs of oxygen atoms and to single oxygen atoms in poly(propylene oxide). The observed glass transition temperature behavior is eludicated

  4. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis.

    Science.gov (United States)

    Dyverfeldt, Petter; Hope, Michael D; Tseng, Elaine E; Saloner, David

    2013-01-01

    The authors sought to measure the turbulent kinetic energy (TKE) in the ascending aorta of patients with aortic stenosis and to assess its relationship to irreversible pressure loss. Irreversible pressure loss caused by energy dissipation in post-stenotic flow is an important determinant of the hemodynamic significance of aortic stenosis. The simplified Bernoulli equation used to estimate pressure gradients often misclassifies the ventricular overload caused by aortic stenosis. The current gold standard for estimation of irreversible pressure loss is catheterization, but this method is rarely used due to its invasiveness. Post-stenotic pressure loss is largely caused by dissipation of turbulent kinetic energy into heat. Recent developments in magnetic resonance flow imaging permit noninvasive estimation of TKE. The study was approved by the local ethics review board and all subjects gave written informed consent. Three-dimensional cine magnetic resonance flow imaging was used to measure TKE in 18 subjects (4 normal volunteers, 14 patients with aortic stenosis with and without dilation). For each subject, the peak total TKE in the ascending aorta was compared with a pressure loss index. The pressure loss index was based on a previously validated theory relating pressure loss to measures obtainable by echocardiography. The total TKE did not appear to be related to global flow patterns visualized based on magnetic resonance-measured velocity fields. The TKE was significantly higher in patients with aortic stenosis than in normal volunteers (p < 0.001). The peak total TKE in the ascending aorta was strongly correlated to index pressure loss (R(2) = 0.91). Peak total TKE in the ascending aorta correlated strongly with irreversible pressure loss estimated by a well-established method. Direct measurement of TKE by magnetic resonance flow imaging may, with further validation, be used to estimate irreversible pressure loss in aortic stenosis. Copyright © 2013 American

  5. Single Photon Counting Performance and Noise Analysis of CMOS SPAD-Based Image Sensors

    Science.gov (United States)

    Dutton, Neale A. W.; Gyongy, Istvan; Parmesan, Luca; Henderson, Robert K.

    2016-01-01

    SPAD-based solid state CMOS image sensors utilising analogue integrators have attained deep sub-electron read noise (DSERN) permitting single photon counting (SPC) imaging. A new method is proposed to determine the read noise in DSERN image sensors by evaluating the peak separation and width (PSW) of single photon peaks in a photon counting histogram (PCH). The technique is used to identify and analyse cumulative noise in analogue integrating SPC SPAD-based pixels. The DSERN of our SPAD image sensor is exploited to confirm recent multi-photon threshold quanta image sensor (QIS) theory. Finally, various single and multiple photon spatio-temporal oversampling techniques are reviewed. PMID:27447643

  6. Voter model with arbitrary degree dependence: clout, confidence and irreversibility

    Science.gov (United States)

    Fotouhi, Babak; Rabbat, Michael G.

    2014-03-01

    The voter model is widely used to model opinion dynamics in society. In this paper, we propose three modifications to incorporate heterogeneity into the model. We address the corresponding oversimplifications of the conventional voter model which are unrealistic. We first consider the voter model with popularity bias. The influence of each node on its neighbors depends on its degree. We find the consensus probabilities and expected consensus times for each of the states. We also find the fixation probability, which is the probability that a single node whose state differs from every other node imposes its state on the entire system. In addition, we find the expected fixation time. Then two other extensions to the model are proposed and the motivations behind them are discussed. The first one is confidence, where in addition to the states of neighbors, nodes take their own state into account at each update. We repeat the calculations for the augmented model and investigate the effects of adding confidence to the model. The second proposed extension is irreversibility, where one of the states is given the property that once nodes adopt it, they cannot switch back. This is motivated by applications where, agents take an irreversible action such as seeing a movie, purchasing a music album online, or buying a new product. The dynamics of densities, fixation times and consensus times are obtained.

  7. The role of donor characteristics and post-granulocyte colony-stimulating factor white blood cell counts in predicting the adverse events and yields of stem cell mobilization.

    Science.gov (United States)

    Chen, Shu-Huey; Yang, Shang-Hsien; Chu, Sung-Chao; Su, Yu-Chieh; Chang, Chu-Yu; Chiu, Ya-Wen; Kao, Ruey-Ho; Li, Dian-Kun; Yang, Kuo-Liang; Wang, Tso-Fu

    2011-05-01

    Granulocyte colony-stimulating factor (G-CSF) is now widely used for stem cell mobilization. We evaluated the role of post-G-CSF white blood cell (WBC) counts and donor factors in predicting adverse events and yields associated with mobilization. WBC counts were determined at baseline, after the third and the fifth dose of G-CSF in 476 healthy donors. Donors with WBC ≥ 50 × 10(3)/μL post the third dose of G-CSF experienced more fatigue, myalgia/arthralgia, and chills, but final post-G-CSF CD34(+) cell counts were similar. Although the final CD34(+) cell count was higher in donors with WBC ≥ 50 × 10(3)/μL post the fifth G-CSF, the incidence of side effects was similar. Females more frequently experienced headache, nausea/anorexia, vomiting, fever, and lower final CD34(+) cell count than did males. Donors with body mass index (BMI) ≥ 25 showed higher incidences of sweat and insomnia as well as higher final CD34(+) cell counts. Donor receiving G-CSF ≥ 10 μg/kg tended to experience bone pain, headache and chills more frequently. Multivariate analysis indicated that female gender is an independent factor predictive of the occurrence of most side effects, except for ECOG > 1 and chills. Higher BMI was also an independent predictor for fatigue, myalgia/arthralgia, and sweat. Higher G-CSF dose was associated with bone pain, while the WBC count post the third G-CSF was associated with fatigue only. In addition, one donor in the study period did not complete the mobilization due to suspected anaphylactoid reaction. Observation for 1 h after the first injection of G-CSF is required to prevent complications from unpredictable side effects.

  8. Hanford whole body counting manual

    International Nuclear Information System (INIS)

    Palmer, H.E.; Brim, C.P.; Rieksts, G.A.; Rhoads, M.C.

    1987-05-01

    This document, a reprint of the Whole Body Counting Manual, was compiled to train personnel, document operation procedures, and outline quality assurance procedures. The current manual contains information on: the location, availability, and scope of services of Hanford's whole body counting facilities; the administrative aspect of the whole body counting operation; Hanford's whole body counting facilities; the step-by-step procedure involved in the different types of in vivo measurements; the detectors, preamplifiers and amplifiers, and spectroscopy equipment; the quality assurance aspect of equipment calibration and recordkeeping; data processing, record storage, results verification, report preparation, count summaries, and unit cost accounting; and the topics of minimum detectable amount and measurement accuracy and precision. 12 refs., 13 tabs

  9. The counting of native blood cells by digital microscopy

    Science.gov (United States)

    Torbin, S. O.; Doubrovski, V. A.; Zabenkov, I. V.; Tsareva, O. E.

    2017-03-01

    An algorithm for photographic images processing of blood samples in its native state was developed to determine the concentration of erythrocytes, leukocytes and platelets without individual separate preparation of cells' samples. Special "photo templates" were suggested to use in order to identify red blood cells. The effect of "highlighting" of leukocytes, which was found by authors, was used to increase the accuracy of this type of cells counting. Finally to raise the resolution of platelets from leukocytes the areas of their photo images were used, but not their sizes. It is shown that the accuracy of cells counting for native blood samples may be comparable with the accuracy of similar studies for smears. At the same time the proposed native blood analysis simplifies greatly the procedure of sample preparation in comparison to smear, permits to move from the detection of blood cells ratio to the determination of their concentrations in the sample.

  10. [Mineral trioxide aggragate pulpotomy for the treatment of immature permanent teeth with irreversible pulpitis: a preliminary clinical study].

    Science.gov (United States)

    Peng, Chufang; Zhao, Yuming; Yang, Yuan; Qin, Man

    2015-12-01

    To evaluate the preliminary clinical effect of mineral trioxide aggragate (MTA) pulpotomy on immature permanent teeth with irreversible pulpitis. Twenty-six immature permanent teeth with irreversible pulpitis were recuited from Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology. These teeth were treated with partial or full pulpotomy according to the condition of pulp bleeding. MTA was used as pulp capping material. Patients were recalled periodically after the treatment. Clinical and radiographic effects were evaluated. At one year follow-up, 20 teeth were evaluated as healed or healing, 2 teeth were evaluated as failure and 4 teeth were dropped out. The success rate was considered 91% (20/22). A dentinal bridge was radiographcally observed underneath the pulpotomy site in 13 teeth(65%, 13/20). MTA pulpotomy is an effective method for the treatment of immature permanent teeth with irreversible pulpitis. But further research with longer follow up period is required.

  11. Behavior of the irreversibility line in the new superconductor La{sub 1.5+x}Ba{sub 1.5+x-y}Ca{sub y}Cu{sub 3}O{sub z}

    Energy Technology Data Exchange (ETDEWEB)

    Parra Vargas, C.A. [Grupo de Fisica de Materiales, Escuela de Fisica, Universidad Pedagogica y Tecnologica de Colombia, Tunja (Colombia); Pimentel, J.L.; Pureur, P. [Instituto de Fisica, Universidade Federal do Rio Grande do Sul, 91501-970 Porto Alegre, RS (Brazil); Landinez Tellez, D.A. [Grupo de Fisica de Nuevos Materiales, Departamento de Fisica, Universidad Nacional de Colombia, AA 5997, Bogota DC (Colombia); Roa-Rojas, J., E-mail: carlos.parra@uptc.edu.co [Grupo de Fisica de Nuevos Materiales, Departamento de Fisica, Universidad Nacional de Colombia, AA 5997, Bogota DC (Colombia)

    2012-08-15

    The irreversibility properties of high-T{sub c} superconductors are of major importance for technological applications. For example, a high irreversibility magnetic field is a more desirable quality for a superconductor . The irreversibility line in the H-T plane is constituted by experimental points, which divides the irreversible and reversible behavior of the magnetization. The irreversibility lines for series of La{sub 1.5+x}Ba{sub 1.5+x-y}Ca{sub y}Cu{sub 3}O{sub z} polycrystalline samples with different doping were investigated. The samples were synthesized using the usual solid estate reaction method. Rietveld-type refinement of x-ray diffraction patterns permitted to determine the crystallization of material in a tetragonal structure. Curves of magnetization ZFC-FC for the system La{sub 1.5+x}Ba{sub 1.5+x-y}Ca{sub y}Cu{sub 3}O{sub z}, were measured in magnetic fields of the 10-20,000 Oe, and allowed to obtain the values for the irreversibility and critical temperatures. The data of irreversibility temperature allowed demarcating the irreversibility line, T{sub irr}(H). Two main lines are used for the interpretation of the irreversibility line: one of those which suppose that the vortexes are activated thermally and the other proposes that associated to T{sub irr} a phase transition occurs. The irreversibility line is described by a power law. The obtained results allow concluding that in the system La{sub 1.5+x}Ba{sub 1.5+x-y}Ca{sub y}Cu{sub 3}O{sub z} a characteristic bend of the Almeida-Thouless (AT) tendency is dominant for low fields and a bend Gabay-Toulouse (GT) behavior for high magnetic fields. This feature of the irreversibility line has been reported as a characteristic of granular superconductors and it corroborates the topological effects of vortexes mentioned by several authors .

  12. Colour quenching corrections on the measurement of {sup 90}Sr through Cerenkov counting

    Energy Technology Data Exchange (ETDEWEB)

    Mosqueda, F. [Dpto. de Fisica Aplicada, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus de El Carmen, 21071 Huelva (Spain)], E-mail: fernando.mosqueda@dfa.uhu.es; Villa, M. [Centro de Investigacion, Tecnologia e Innovacion, Universidad de Sevilla, Av. Reina Mercedes 4B, E41012 Sevilla (Spain); Vaca, F.; Bolivar, J.P. [Dpto. de Fisica Aplicada, Facultad de Ciencias Experimentales, Universidad de Huelva, Campus de El Carmen, 21071 Huelva (Spain)

    2007-12-05

    The determination of {sup 90}Sr through the Cerenkov radiation emitted by its descendant {sup 90}Y is a well-known method and firmly established in literature. Nevertheless, in order to obtain an accurate result based on a Cerenkov measurement, the experimental work must be extremely rigorous because the efficiency of Cerenkov counting is especially sensitive to the presence of colour. Any traces of colour in the sample produce a decrease in the number of photons detected in the photomultipliers and, therefore, this might cause a diminution in Cerenkov counting efficiency. It is essential not only to detect the effect of colour quenching in the sample but also to correct the decrease in counting efficiency. For this reason, colour quenching correction curves versus counting efficiency are usually done when measuring through Cerenkov counting. One of the most widely used techniques to evaluate colour quenching in these measurements is the channel ratio method, which consists of the measurement of the shift of the spectrum measuring the ratio of counts in two different windows. The selection of the windows for the application of the corrections might have an influence on the quality of the fitting parameters of the correction curves efficiency versus colour quenching degree and hence on the final {sup 90}Sr result. This work is focused on the calculation of the counting efficiency decrease using the channel ratio method and on obtaining the best fitting correction curve. For this purpose, empirical curves obtained through artificial quenchers have been studied and the results have been tested in real samples. Additionally, given that the Packard Tri-Carb 3170 TR/SL liquid scintillation counter is a novel detector for use in Cerenkov counting, the previous calibration of the Tri-Carb 3170 TR/SL detector, necessary for the measurement of {sup 90}Sr, is included.

  13. Effect of Buffered 4% Lidocaine on the Success of the Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind Study.

    Science.gov (United States)

    Schellenberg, Jared; Drum, Melissa; Reader, Al; Nusstein, John; Fowler, Sara; Beck, Mike

    2015-06-01

    Medical studies have suggested that buffering local anesthetic may increase the ability to achieve anesthesia. The purpose of this study was to determine the effect of 4% buffered lidocaine on the anesthetic success of the inferior alveolar nerve (IAN) block in patients experiencing symptomatic irreversible pulpitis. One hundred emergency patients diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received a conventional IAN block using either 2.8 mL 4% lidocaine with 1:100,000 epinephrine or 2.8 mL 4% lidocaine with 1:100,000 epinephrine buffered with sodium bicarbonate in a double-blind manner. For the buffered solution, each cartridge was buffered with 8.4% sodium bicarbonate using the OnPharma (Los Gatos, CA) system to produce a final concentration of 0.18 mEq/mL sodium bicarbonate. Fifteen minutes after administration of the IAN block, profound lip numbness was confirmed, and endodontic access was initiated. Success was defined as no or mild pain (≤54 mm on a 170-mm visual analog scale) on access or instrumentation of the root canal. The success rate for the IAN block was 32% for the buffered group and 40% for the nonbuffered group, with no significant difference (P = .4047) between the groups. Injection pain ratings for the IAN block were not significantly (P = .9080) different between the 2 formulations. For mandibular posterior teeth, a 4% buffered lidocaine formulation did not result in a statistically significant increase in the success rate or a decrease in injection pain of the IAN block in patients with symptomatic irreversible pulpitis. Copyright © 2015. Published by Elsevier Inc.

  14. CalCOFI Egg Counts

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fish egg counts and standardized counts for eggs captured in CalCOFI icthyoplankton nets (primarily vertical [Calvet or Pairovet], oblique [bongo or ring nets], and...

  15. Count-doubling time safety circuit

    International Nuclear Information System (INIS)

    Keefe, D.J.; McDowell, W.P.; Rusch, G.K.

    1981-01-01

    There is provided a nuclear reactor count-factor-increase time monitoring circuit which includes a pulse-type neutron detector, and means for counting the number of detected pulses during specific time periods. Counts are compared and the comparison is utilized to develop a reactor scram signal, if necessary

  16. Count-doubling time safety circuit

    Science.gov (United States)

    Rusch, Gordon K.; Keefe, Donald J.; McDowell, William P.

    1981-01-01

    There is provided a nuclear reactor count-factor-increase time monitoring circuit which includes a pulse-type neutron detector, and means for counting the number of detected pulses during specific time periods. Counts are compared and the comparison is utilized to develop a reactor scram signal, if necessary.

  17. The Big Pumpkin Count.

    Science.gov (United States)

    Coplestone-Loomis, Lenny

    1981-01-01

    Pumpkin seeds are counted after students convert pumpkins to jack-o-lanterns. Among the activities involved, pupils learn to count by 10s, make estimates, and to construct a visual representation of 1,000. (MP)

  18. Comparing distribution models for small samples of overdispersed counts of freshwater fish

    Science.gov (United States)

    Vaudor, Lise; Lamouroux, Nicolas; Olivier, Jean-Michel

    2011-05-01

    The study of species abundance often relies on repeated abundance counts whose number is limited by logistic or financial constraints. The distribution of abundance counts is generally right-skewed (i.e. with many zeros and few high values) and needs to be modelled for statistical inference. We used an extensive dataset involving about 100,000 fish individuals of 12 freshwater fish species collected in electrofishing points (7 m 2) during 350 field surveys made in 25 stream sites, in order to compare the performance and the generality of four distribution models of counts (Poisson, negative binomial and their zero-inflated counterparts). The negative binomial distribution was the best model (Bayesian Information Criterion) for 58% of the samples (species-survey combinations) and was suitable for a variety of life histories, habitat, and sample characteristics. The performance of the models was closely related to samples' statistics such as total abundance and variance. Finally, we illustrated the consequences of a distribution assumption by calculating confidence intervals around the mean abundance, either based on the most suitable distribution assumption or on an asymptotical, distribution-free (Student's) method. Student's method generally corresponded to narrower confidence intervals, especially when there were few (≤3) non-null counts in the samples.

  19. Irreversibility of world-sheet renormalization group flow

    International Nuclear Information System (INIS)

    Oliynyk, T.; Suneeta, V.; Woolgar, E.

    2005-01-01

    We demonstrate the irreversibility of a wide class of world-sheet renormalization group (RG) flows to first order in α ' in string theory. Our techniques draw on the mathematics of Ricci flows, adapted to asymptotically flat target manifolds. In the case of somewhere-negative scalar curvature (of the target space), we give a proof by constructing an entropy that increases monotonically along the flow, based on Perelman's Ricci flow entropy. One consequence is the absence of periodic solutions, and we are able to give a second, direct proof of this. If the scalar curvature is everywhere positive, we instead construct a regularized volume to provide an entropy for the flow. Our results are, in a sense, the analogue of Zamolodchikov's c-theorem for world-sheet RG flows on noncompact spacetimes (though our entropy is not the Zamolodchikov C-function)

  20. Modeling the frequency-dependent detective quantum efficiency of photon-counting x-ray detectors.

    Science.gov (United States)

    Stierstorfer, Karl

    2018-01-01

    To find a simple model for the frequency-dependent detective quantum efficiency (DQE) of photon-counting detectors in the low flux limit. Formula for the spatial cross-talk, the noise power spectrum and the DQE of a photon-counting detector working at a given threshold are derived. Parameters are probabilities for types of events like single counts in the central pixel, double counts in the central pixel and a neighboring pixel or single count in a neighboring pixel only. These probabilities can be derived in a simple model by extensive use of Monte Carlo techniques: The Monte Carlo x-ray propagation program MOCASSIM is used to simulate the energy deposition from the x-rays in the detector material. A simple charge cloud model using Gaussian clouds of fixed width is used for the propagation of the electric charge generated by the primary interactions. Both stages are combined in a Monte Carlo simulation randomizing the location of impact which finally produces the required probabilities. The parameters of the charge cloud model are fitted to the spectral response to a polychromatic spectrum measured with our prototype detector. Based on the Monte Carlo model, the DQE of photon-counting detectors as a function of spatial frequency is calculated for various pixel sizes, photon energies, and thresholds. The frequency-dependent DQE of a photon-counting detector in the low flux limit can be described with an equation containing only a small set of probabilities as input. Estimates for the probabilities can be derived from a simple model of the detector physics. © 2017 American Association of Physicists in Medicine.

  1. Trigeminocardiac reflex during non-surgical root canal treatment of teeth with irreversible pulpitis

    Directory of Open Access Journals (Sweden)

    James I.-Sheng Huang

    2018-06-01

    Full Text Available Background/Purpose: Trigeminocardiac reflex (TCR is a unique clinical incident of acute change in hemodynamic balance, which may lead to hypotension, bradycardia, and even clinical crisis. Up to date, no study so far considers the impact of non-surgical root canal treatment (NSRCT of irreversible pulpitis teeth under either local infiltration or block anesthesia on hemodynamic change possibly related to TCR. Methods: This study enrolled 111 patients with 138 irreversible pulpitis teeth that were treated by two sessions of NSRCT. The first session involved mainly the removal of vital pulp tissue with the direct stimulation of the dental branches of the trigeminal nerve, and the second session included the root canal enlargement and debridement with minimal disturbance to the dental branches of the trigeminal nerve. Vital signs mainly the blood pressure were recorded during both NSRCT sessions. Results: The incidences of NSRCT patients with MABP decrease ≧10%, ≧15%, or ≧20% were all significantly higher in the first NSRCT session than in the second NSRCT session (all the P-values < 0.001. In the first NSRCT session, the incidence of patients with MABP decrease ≧10% was significantly associated with tooth type. For both upper and lower teeth, the patients with premolars treated by NSRCR had significantly higher incidences of MABP decrease ≧10% than those with either anterior or molar teeth treated by NSRCR (all the P-values < 0.05. Conclusion: We conclude that vital pulp extirpation may lead to a substantial drop in patient's blood pressure possibly related to TCR. Keywords: Trigeminocardiac reflex, Non-surgical root canal treatment, Irreversible pulpitis, Mean arterial blood pressure, Hypotension, Teeth

  2. Free parameter, figure of merit and ionization quench in liquid scintillation counting

    International Nuclear Information System (INIS)

    Carles, P. Grau; Malonda, A. Grau

    2001-01-01

    A statistical study of the detection process demonstrates that the free parameter is essential to compute the counting efficiency in both CIEMAT/NIST and TDCR methods. An analysis of the computed counting efficiencies shows the uselessness of old definition of the figure of merit. A new definition is required and we adopt the idea of taking quantities related with the output of the photomultiplier. In addition, we justify the application of the chemical quenching simulation with the electronic variation of the photomultiplier gain. Finally, we describe a new procedure to determine the figure of merit and the optimum ionization-quenching factor from the pulse spectrum of different radionuclides. The robustness of the new procedure is tested with three different sets of stopping power for low-energy electrons

  3. Buccal infiltration versus inferior alveolar nerve block in mandibular 2nd premolars with irreversible pulpitis.

    Science.gov (United States)

    Yilmaz, K; Tunga, U; Ozyurek, T

    2018-04-01

    The purpose of this study is to compare the success rates of inferior alveolar nerve block (IANB) and buccal infiltration anesthesia of mandibular second premolar with irreversible pulpitis and to evaluate the level of patient discomfort with these methods. Forty patients, who had irreversible pulpitis in the mandibular 2 nd premolar teeth, were included in the study. Patients were randomly distributed in two groups. In one group IANB, in the other group buccal infiltration anesthesia were performed. The efficacy of these two different anesthesia techniques on the related teeth was investigated with the Heft-Parker visual analog scale. In addition, with a pulse oximetry device, the changes in the patients' heart rates were compared between the groups. The obtained data were evaluated statistically. Both anesthesia techniques reduced the pain significantly in patients before the administration (P 0.05). Both of the anesthesia techniques increased the heart rate (P < 0.05). The increase in the heart rate of the patients was significantly higher in the buccal infiltration anesthesia group than the other anesthesia group (P < 0.05). Within the limitation of this in vivo study, there was no difference between the efficacies of the buccal infiltration anesthesia and IANB anesthesia in the mandibular 2 nd premolar teeth with irreversible pulpitis. Buccal infiltration anesthesia caused more discomfort in the patients compared with the IANB during the administration.

  4. Endothelial dysfunction and atherosclerosis in children with irreversible pulmonary hypertension due to congenital heart disease

    International Nuclear Information System (INIS)

    Çiftel, Murat; Şimşek, Ayse; Turan, Özlem; Kardelen, Firat; Akçurin, Gayaz; Ertuğ, Halil

    2012-01-01

    To assess endothelial dysfunction and the risk for coronary atherosclerosis in children with irreversible pulmonary hypertension due to congenital heart disease (CHD). The study included 18 cyanotic patients (the mean age was 12.28 ± 3.26 years) who developed irreversible pulmonary hypertension due to cyanotic and acyanotic CHDs, and 18 control patients (the mean age was 11.78 ± 3.00 years). Study groups were compared for flow-mediated dilatation (FMD), carotid intima media thickness (CIMT) and atherosclerotic risk factors. Compared to the control group, the mean FMD was significantly reduced in the cyanotic group (5.26 ± 2.42% and 9.48 ± 2.60%, respectively; P-value < 0.001). No significant difference was observed between the groups in CIMT (0.41 ± 0.08 mm and 0.39 ± 0.06 mm, respectively; P-value = 0.299). The levels of total cholesterol, low-density lipoprotein–cholesterol and very low-density lipoprotein–cholesterol were statistically significantly lower compared tothe control group (P-value = 0.001, 0.006 and 0.014, respectively), whereas no statistically significant difference was found in the levels of high-density lipoprotein–cholesterol and triglycerides (P-value = 0.113 and 0.975, respectively). Systemic endothelial dysfunction in children with irreversible pulmonary hypertension due to CHD was noted but there was no increased risk for atherosclerosis

  5. Galaxy number counts: Pt. 2

    International Nuclear Information System (INIS)

    Metcalfe, N.; Shanks, T.; Fong, R.; Jones, L.R.

    1991-01-01

    Using the Prime Focus CCD Camera at the Isaac Newton Telescope we have determined the form of the B and R galaxy number-magnitude count relations in 12 independent fields for 21 m ccd m and 19 m ccd m 5. The average galaxy count relations lie in the middle of the wide range previously encompassed by photographic data. The field-to-field variation of the counts is small enough to define the faint (B m 5) galaxy count to ±10 per cent and this variation is consistent with that expected from galaxy clustering considerations. Our new data confirm that the B, and also the R, galaxy counts show evidence for strong galaxy luminosity evolution, and that the majority of the evolving galaxies are of moderately blue colour. (author)

  6. Platelet count evolution as a predictor of outcome after splenectomy for immune thrombocytopenic purpura.

    Science.gov (United States)

    Kim, Moonhwan; Park, Keun Myoung; Shin, Woo Young; Choe, Yun-Mee; Lee, Keon-Young; Ahn, Seung-Ik

    2017-04-01

    Splenectomy is the definitive second-line therapy for refractory immune thrombocytopenic purpura (ITP), and has a reported response rate of 50-80%. Medical attention should be reconsidered when there is no evidence of accessory spleen in refractory ITP patients after splenectomy. The purpose of this study was to determine whether platelet count evolution differs between patients with a successful or unsuccessful result after splenectomy for ITP. Archived records of 104 consecutive patients that underwent splenectomy for ITP were reviewed. Patients were divided into two groups (failures and successes) using a final follow-up platelet count of 100,000/μL as a cut-off. Platelet count evolutions in these two groups were compared using the Student's t test. Successes and failures were found to have significantly different platelet counts from two days postoperatively (P = 0.016). The area under the receiver operating characteristic curve was 0.630 (95% confidence interval, 0.518-0.741, P = 0.030), and when a cut-off value of 100,000/μL was used, sensitivity and specificity were 68.2 and 51.2%, respectively. To obtain positive and negative predictive values exceeding 50%, additional platelet counts were required at one week and one month after splenectomy. We propose a protocol for ITP follow-up after splenectomy.

  7. Irreversible dilation of NaCl contaminated lime-cement mortar due to crystallization cycles

    NARCIS (Netherlands)

    Lubelli, B.; van Hees, R.P.J.; Huinink, H.P.; Groot, C.J.W.P.

    2006-01-01

    The mechanism of damage occurring in NaCl contaminated materials has not been clarified yet. Apart from crystn. pressure, other hypotheses have been proposed to explain the cause of decay. Irreversible dilation has been obsd. in a few cases but has never been studied in a more systematic way. The

  8. Alpha 2-adrenergic receptor turnover in adipose tissue and kidney: irreversible blockade of alpha 2-adrenergic receptors by benextramine

    International Nuclear Information System (INIS)

    Taouis, M.; Berlan, M.; Lafontan, M.

    1987-01-01

    The recovery of post- and extrasynaptic alpha 2-adrenergic receptor-binding sites was studied in vivo in male golden hamsters after treatment with an irreversible alpha-adrenoceptor antagonist benextramine, a tetramine disulfide that possesses a high affinity for alpha 2-binding sites. The kidney alpha 2-adrenergic receptor number was measured with [ 3 H]yohimbine, whereas [ 3 H]clonidine was used for fat cell and brain membrane alpha 2-binding site identification. Benextramine treatment of fat cell, kidney, and brain membranes reduced or completely suppressed, in an irreversible manner, [ 3 H] clonidine and [ 3 H]yohimbine binding without modifying adenosine (A1-receptor) and beta-adrenergic receptor sites. This irreversible binding was also found 1 and 2 hr after intraperitoneal administration of benextramine to the hamsters. Although it bound irreversibly to peripheral and central alpha 2-adrenergic receptors on isolated membranes, benextramine was unable to cross the blood-brain barrier of the hamster at the concentrations used (10-20 mg/kg). After the irreversible blockade, alpha 2-binding sites reappeared in kidney and adipose tissue following a monoexponential time course. Recovery of binding sites was more rapid in kidney than in adipose tissue; the half-lives of the receptor were 31 and 46 hr, respectively in the tissues. The rates of receptor production were 1.5 and 1.8 fmol/mg of protein/hr in kidney and adipose tissue. Reappearance of alpha 2-binding sites was associated with a rapid recovery of function (antilipolytic potencies of alpha 2-agonists) in fat cells inasmuch as occupancy of 15% of [ 3 H]clonidine-binding sites was sufficient to promote 40% inhibition of lipolysis. Benextramine is a useful tool to estimate turnover of alpha 2-adrenergic receptors under normal and pathological situations

  9. Counting statistics in radioactivity measurements

    International Nuclear Information System (INIS)

    Martin, J.

    1975-01-01

    The application of statistical methods to radioactivity measurement problems is analyzed in several chapters devoted successively to: the statistical nature of radioactivity counts; the application to radioactive counting of two theoretical probability distributions, Poisson's distribution law and the Laplace-Gauss law; true counting laws; corrections related to the nature of the apparatus; statistical techniques in gamma spectrometry [fr

  10. Correlation between total lymphocyte count, hemoglobin, hematocrit and CD4 count in HIV patients in Nigeria.

    Science.gov (United States)

    Emuchay, Charles Iheanyichi; Okeniyi, Shemaiah Olufemi; Okeniyi, Joshua Olusegun

    2014-04-01

    The expensive and technology limited setting of CD4 count testing is a major setback to the initiation of HAART in a resource limited country like Nigeria. Simple and inexpensive tools such as Hemoglobin (Hb) measurement and Total Lymphocyte Count (TLC) are recommended as substitute marker. In order to assess the correlations of these parameters with CD4 count, 100 "apparently healthy" male volunteers tested HIV positive aged ≥ 20 years but ≤ 40 years were recruited and from whom Hb, Hct, TLC and CD4 count were obtained. The correlation coefficients, R, the Nash-Sutcliffe Coefficient of Efficiency (CoE) and the p-values of the ANOVA model of Hb, Hct and TLC with CD4 count were assessed. The assessments show that there is no significant relationship of any of these parameters with CD4 count and the correlation coefficients are very weak. This study shows that Hb, Hct and TLC cannot be substitute for CD4 count as this might lead to certain individuals' deprivation of required treatment.

  11. X-tip intraosseous injection system as a primary anesthesia for irreversible pulpitis of posterior mandibular teeth: A randomized clinical trail

    OpenAIRE

    Razavian, Hamid; Kazemi, Shantia; Khazaei, Saber; Jahromi, Maryam Zare

    2013-01-01

    Background: Successful anesthesia during root canal therapy may be difficult to obtain. Intraosseous injection significantly improves anesthesia′s success as a supplemental pulpal anesthesia, particularly in cases of irreversible pulpitis. The aim of this study was to compare the efficacy of X-tip intraosseous injection and inferior alveolar nerve (IAN) block in primary anesthesia for mandibular posterior teeth with irreversible pulpitis. Materials and Methods: Forty emergency patients wi...

  12. It counts who counts: an experimental evaluation of the importance of observer effects on spotlight count estimates

    DEFF Research Database (Denmark)

    Sunde, Peter; Jessen, Lonnie

    2013-01-01

    observers with respect to their ability to detect and estimate distance to realistic animal silhouettes at different distances. Detection probabilities were higher for observers experienced in spotlighting mammals than for inexperienced observers, higher for observers with a hunting background compared...... with non-hunters and decreased as function of age but were independent of sex or educational background. If observer-specific detection probabilities were applied to real counting routes, point count estimates from inexperienced observers without a hunting background would only be 43 % (95 % CI, 39...

  13. Performance evaluation of an irreversible Miller cycle comparing FTT (finite-time thermodynamics) analysis and ANN (artificial neural network) prediction

    International Nuclear Information System (INIS)

    Mousapour, Ashkan; Hajipour, Alireza; Rashidi, Mohammad Mehdi; Freidoonimehr, Navid

    2016-01-01

    In this paper, the first and second-laws efficiencies are applied to performance analysis of an irreversible Miller cycle. In the irreversible cycle, the linear relation between the specific heat of the working fluid and its temperature, the internal irreversibility described using the compression and expansion efficiencies, the friction loss computed according to the mean velocity of the piston and the heat-transfer loss are considered. The effects of various design parameters, such as the minimum and maximum temperatures of the working fluid and the compression ratio on the power output and the first and second-laws efficiencies of the cycle are discussed. In the following, a procedure named ANN is used for predicting the thermal efficiency values versus the compression ratio, and the minimum and maximum temperatures of the Miller cycle. Nowadays, Miller cycle is widely used in the automotive industry and the obtained results of this study will provide some significant theoretical grounds for the design optimization of the Miller cycle. - Highlights: • The performance of an irreversible Miller cycle is investigated using FFT. • The effects of design parameters on the performance of the cycle are investigated. • ANN is applied to predict the thermal efficiency and the power output values. • There is an excellent correlation between FTT and ANN data. • ANN can be applied to predict data where FTT analysis has not been performed.

  14. You can count on the motor cortex: Finger counting habits modulate motor cortex activation evoked by numbers

    Science.gov (United States)

    Tschentscher, Nadja; Hauk, Olaf; Fischer, Martin H.; Pulvermüller, Friedemann

    2012-01-01

    The embodied cognition framework suggests that neural systems for perception and action are engaged during higher cognitive processes. In an event-related fMRI study, we tested this claim for the abstract domain of numerical symbol processing: is the human cortical motor system part of the representation of numbers, and is organization of numerical knowledge influenced by individual finger counting habits? Developmental studies suggest a link between numerals and finger counting habits due to the acquisition of numerical skills through finger counting in childhood. In the present study, digits 1 to 9 and the corresponding number words were presented visually to adults with different finger counting habits, i.e. left- and right-starters who reported that they usually start counting small numbers with their left and right hand, respectively. Despite the absence of overt hand movements, the hemisphere contralateral to the hand used for counting small numbers was activated when small numbers were presented. The correspondence between finger counting habits and hemispheric motor activation is consistent with an intrinsic functional link between finger counting and number processing. PMID:22133748

  15. Irreversibility Curve on Y1–xLuxBa2Cu3O7–δ (x=0.4, 0.5 and 0.6) superconducting

    International Nuclear Information System (INIS)

    Grimaldos, J F Cepeda; Supelano G, I; Santos, A Sarmiento; Chiquillo, M V; Martínez B, D; Vargas, C A Parra

    2014-01-01

    The irreversibility line in the H–T plane divides the irreversible and reversible behaviour of the magnetization which is of importance for the characterization of high T c superconductors. In this work, we report the production of Y 1–X Lu X Ba 2 Cu 3 O 7–δ (X=0.4, 0.5 and 0.6) superconducting system using the usual solid state reaction method. The irreversibility line H–T plane for the Y 1–X Lu X Ba 2 Cu 3 O 7–δ polycrystalline sample was investigated. The curves of magnetization ZFC (cero field cooled)- FC (field cooled) were measured in magnetic fields between 100 Oe and 4000 Oe, and allowed to obtain the values for irreversibility and critical temperatures

  16. Total lymphocyte count and subpopulation lymphocyte counts in relation to dietary intake and nutritional status of peritoneal dialysis patients.

    Science.gov (United States)

    Grzegorzewska, Alicja E; Leander, Magdalena

    2005-01-01

    Dietary deficiency causes abnormalities in circulating lymphocyte counts. For the present paper, we evaluated correlations between total and subpopulation lymphocyte counts (TLC, SLCs) and parameters of nutrition in peritoneal dialysis (PD) patients. Studies were carried out in 55 patients treated with PD for 22.2 +/- 11.4 months. Parameters of nutritional status included total body mass, lean body mass (LBM), body mass index (BMI), and laboratory indices [total protein, albumin, iron, ferritin, and total iron binding capacity (TIBC)]. The SLCs were evaluated using flow cytometry. Positive correlations were seen between TLC and dietary intake of niacin; TLC and CD8 and CD16+56 counts and energy delivered from protein; CD4 count and beta-carotene and monounsaturated fatty acids 17:1 intake; and CD19 count and potassium, copper, vitamin A, and beta-carotene intake. Anorexia negatively influenced CD19 count. Serum albumin showed correlations with CD4 and CD19 counts, and LBM with CD19 count. A higher CD19 count was connected with a higher red blood cell count, hemoglobin, and hematocrit. Correlations were observed between TIBC and TLC and CD3 and CD8 counts, and between serum Fe and TLC and CD3 and CD4 counts. Patients with a higher CD19 count showed a better clinical-laboratory score, especially less weakness. Patients with a higher CD4 count had less expressed insomnia. Quantities of ingested vitamins and minerals influence lymphocyte counts in the peripheral blood of PD patients. Evaluation of TLC and SLCs is helpful in monitoring the effectiveness of nutrition in these patients.

  17. Treatment Outcomes of Full Pulpotomy as an Alternative to Tooth Extraction in Molars with Hyperplastic/Irreversible Pulpitis: A Case Report

    Science.gov (United States)

    Asgary, Saeed; Verma, Prashant; Nosrat, Ali

    2017-01-01

    Root canal therapy (RCT) is a common and successful treatment for irreversible pulpitis due to carious pulp exposure in mature permanent teeth. However, it is often an expensive procedure, may require multiple appointments, and requires a high level of training and clinical skill, specifically in molars. Uninsured patients, low-income patients, and patients with limited access to specialist care often elect for extraction of restorable teeth with irreversible pulpitis. There is a need for an alternative affordable treatment option to preserve their teeth and maintain chewing function. A case of pulpotomy using calcium-enriched mixture (CEM) cement in two maxillary molars (#14 and 15) in a healthy 36-year-old patient is presented. Both teeth were diagnosed with symptomatic hyperplastic/irreversible pulpitis. Patient did not have dental insurance, was unable to afford RCT, and refused to extract the teeth. CEM pulpotomy and amalgam build-ups were done as an alternative to extraction. At 2-year recall, both teeth were functional with no signs/symptoms of inflammation/infection. Periapical radiographs and 3D images showed normal PDL around all roots. Pulpotomy with CEM biomaterial might be a viable alternative to tooth extraction for mature permanent teeth with hyperplastic/irreversible pulpitis, and can result in long-term tooth retention and improved oral health. PMID:28512498

  18. Monopolistic pricing power for transgenic crops when technology adopters face irreversible benefits and costs

    NARCIS (Netherlands)

    Weaver, R.D.; Wesseler, J.H.H.

    2004-01-01

    Pricing of biotechnology innovation under a patent grant is reconsidered in a model with uncertain returns and irreversible costs and benefits. Past results oil restricted monopoly pricing in the presence of competing technologies showed that pricing power is reduced. The timing of adoption of an

  19. Unravelling the origin of irreversible capacity loss in NaNiO 2 for high voltage sodium ion batteries

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Liguang; Wang, Jiajun; Zhang, Xiaoyi; Ren, Yang; Zuo, Pengjian; Yin, Geping; Wang, Jun

    2017-04-01

    Layered transition metal compounds have attracted much attention due to their high theoretical capacity and energy density for sodium ion batteries. However, this kind of material suffers from serious irreversible capacity decay during the charge and discharge process. Here, using synchrotron-based operando transmission X-ray microscopy and high-energy X-ray diffraction combined with electrochemical measurements, the visualization of the dissymmetric phase transformation and structure evolution mechanism of layered NaNiO2 material during initial charge and discharge cycles are clarified. Phase transformation and deformation of NaNiO2 during the voltage range of below 3.0 V and over 4.0 V are responsible for the irreversible capacity loss during the first cycling, which is also confirmed by the evolution of reaction kinetics behavior obtained by the galvanostatic intermittent titration technique. These findings reveal the origin of the irreversibility of NaNiO2 and offer valuable insight into the phase transformation mechanism, which will provide underlying guidance for further development of high-performance sodium ion batteries.

  20. Heterogeneous counting on filter support media

    International Nuclear Information System (INIS)

    Long, E.; Kohler, V.; Kelly, M.J.

    1976-01-01

    Many investigators in the biomedical research area have used filter paper as the support for radioactive samples. This means that a heterogeneous counting of sample sometimes results. The count rate of a sample on a filter will be affected by positioning, degree of dryness, sample application procedure, the type of filter, and the type of cocktail used. Positioning of the filter (up or down) in the counting vial can cause a variation of 35% or more when counting tritiated samples on filter paper. Samples of varying degrees of dryness when added to the counting cocktail can cause nonreproducible counts if handled improperly. Count rates starting at 2400 CPM initially can become 10,000 CPM in 24 hours for 3 H-DNA (deoxyribonucleic acid) samples dried on standard cellulose acetate membrane filters. Data on cellulose nitrate filters show a similar trend. Sample application procedures in which the sample is applied to the filter in a small spot or on a large amount of the surface area can cause nonreproducible or very low counting rates. A tritiated DNA sample, when applied topically, gives a count rate of 4,000 CPM. When the sample is spread over the whole filter, 13,400 CPM are obtained with a much better coefficient of variation (5% versus 20%). Adding protein carrier (bovine serum albumin-BSA) to the sample to trap more of the tritiated DNA on the filter during the filtration process causes a serious beta absorption problem. Count rates which are one-fourth the count rate applied to the filter are obtained on calibrated runs. Many of the problems encountered can be alleviated by a proper choice of filter and the use of a liquid scintillation cocktail which dissolves the filter. Filter-Solv has been used to dissolve cellulose nitrate filters and filters which are a combination of cellulose nitrate and cellulose acetate. Count rates obtained for these dissolved samples are very reproducible and highly efficient

  1. Comprehensive performance analyses and optimization of the irreversible thermodynamic cycle engines (TCE) under maximum power (MP) and maximum power density (MPD) conditions

    International Nuclear Information System (INIS)

    Gonca, Guven; Sahin, Bahri; Ust, Yasin; Parlak, Adnan

    2015-01-01

    This paper presents comprehensive performance analyses and comparisons for air-standard irreversible thermodynamic cycle engines (TCE) based on the power output, power density, thermal efficiency, maximum dimensionless power output (MP), maximum dimensionless power density (MPD) and maximum thermal efficiency (MEF) criteria. Internal irreversibility of the cycles occurred during the irreversible-adiabatic processes is considered by using isentropic efficiencies of compression and expansion processes. The performances of the cycles are obtained by using engine design parameters such as isentropic temperature ratio of the compression process, pressure ratio, stroke ratio, cut-off ratio, Miller cycle ratio, exhaust temperature ratio, cycle temperature ratio and cycle pressure ratio. The effects of engine design parameters on the maximum and optimal performances are investigated. - Highlights: • Performance analyses are conducted for irreversible thermodynamic cycle engines. • Comprehensive computations are performed. • Maximum and optimum performances of the engines are shown. • The effects of design parameters on performance and power density are examined. • The results obtained may be guidelines to the engine designers

  2. Putative Stem Cells in Human Dental Pulp with Irreversible Pulpitis-An Exploratory Study

    Science.gov (United States)

    Wang, Z.; Pan, J.; Wright, JT; Bencharit, S.; Zhang, S.; Everett, ET; Teixeira, FB; Preisser, JS

    2010-01-01

    Introduction Although human dental pulp stem cells isolated from healthy teeth have been extensively characterized, it is unknown whether stem cells also exist in clinically compromised teeth with irreversible pulpitis. Here we explored whether cells retrieved from clinically compromised dental pulp have stem cell-like properties. Methods Pulp cells were isolated from healthy teeth (control group) and from teeth with clinically diagnosed irreversible pulpitis (diseased group). Cell proliferation, stem cell marker STRO-1 expression and cell odonto-osteo-genic differentiation competence were compared. Results Cells from the diseased group demonstrated decreased colony formation capacity and a slightly decreased cell proliferation rate but had similar STRO-1 expression, and exhibited a similar percentage of positive ex vivo osteogenic induction and dentin sialophosphoprotein expression from STRO-1-enriched pulp cells. Conclusion Our study provides preliminary evidence that clinically compromised dental pulp may contain putative cells with certain stem cell properties. Further characterization of these cells will provide insight regarding whether they could serve as a source of endogenous multipotent cells in tissue regeneration based dental pulp therapy. PMID:20416426

  3. The dependence of the counting efficiency of Marinelli beakers for environmental samples on the density of the samples

    International Nuclear Information System (INIS)

    Alfassi, Z.B.; Lavi, N.

    2005-01-01

    The effect of the density of the radioactive material packed in a Marinelli beaker on the counting efficiency was studied. It was found that for all densities (0.4-1.7g/cm 3) studied the counting efficiency (ε) fits the linear log-log dependence on the photon energy (E) above 200keV, i.e. obeying the equation ε=αE β (α, β-parameters). It was found that for each photon energy the counting efficiency is linearly dependent on the density (ρ) of the matrix. ε=a-bρ (a, b-parameters). The parameters of the linear dependence are energy dependent (linear log-log dependence), leading to a final equation for the counting efficiency of Marinelli beaker involving both density of the matrix and the photon energy: ε=α 1 .E β 1 -α 2 E β 2 ρ

  4. LAWRENCE RADIATION LABORATORY COUNTING HANDBOOK

    Energy Technology Data Exchange (ETDEWEB)

    Group, Nuclear Instrumentation

    1966-10-01

    The Counting Handbook is a compilation of operational techniques and performance specifications on counting equipment in use at the Lawrence Radiation Laboratory, Berkeley. Counting notes have been written from the viewpoint of the user rather than that of the designer or maintenance man. The only maintenance instructions that have been included are those that can easily be performed by the experimenter to assure that the equipment is operating properly.

  5. Plasma Membrane ATPase Activity following Reversible and Irreversible Freezing Injury 1

    Science.gov (United States)

    Iswari, S.; Palta, Jiwan P.

    1989-01-01

    Plasma membrane ATPase has been proposed as a site of functional alteration during early stages of freezing injury. To test this, plasma membrane was purified from Solanum leaflets by a single step partitioning of microsomes in a dextran-polyethylene glycol two phase system. Addition of lysolecithin in the ATPase assay produced up to 10-fold increase in ATPase activity. ATPase activity was specific for ATP with a Km around 0.4 millimolar. Presence of the ATPase enzyme was identified by immunoblotting with oat ATPase antibodies. Using the phase partitioning method, plasma membrane was isolated from Solanum commersonii leaflets which had four different degrees of freezing damage, namely, slight (reversible), partial (partially reversible), substantial and total (irreversible). With slight (reversible) damage the plasma membrane ATPase specific activity increased 1.5- to 2-fold and its Km was decreased by about 3-fold, whereas the specific activity of cytochrome c reductase and cytochrome c oxidase in the microsomes were not different from the control. However, with substantial (lethal, irreversible) damage, there was a loss of membrane protein, decrease in plasma membrane ATPase specific activity and decrease in Km, while cytochrome c oxidase and cytochrome c reductase were unaffected. These results support the hypothesis that plasma membrane ATPase is altered by slight freeze-thaw stress. Images Figure 1 Figure 2 PMID:16666856

  6. Optimal thermoeconomic performance of an irreversible regenerative ferromagnetic Ericsson refrigeration cycle

    International Nuclear Information System (INIS)

    Xu, Zhichao; Guo, Juncheng; Lin, Guoxing; Chen, Jincan

    2016-01-01

    On the basis of the Langevin theory of classical statistical mechanics, the magnetization, entropy, and iso-field heat capacity of ferromagnetic materials are analyzed and their mathematical expressions are derived. An irreversible regenerative Ericsson refrigeration cycle by using a ferromagnetic material as the working substance is established, in which finite heat capacity rates of low and high temperature reservoirs, non-perfect regenerative heat of the refrigeration cycle, additional regenerative heat loss, etc. are taken into account. Based on the regenerative refrigeration cycle model, a thermoeconomic function is introduced as one objective function and optimized with respect to the temperatures of the working substance in the two iso-thermal processes. By means of numerical calculation, the effects of the effective factor of the heat exchangers in high/low temperature reservoir sides, efficiency of the regenerator, heat capacity rate of the low temperature reservoir, and applied magnetic field on the optimal thermoeconomic function as well as the corresponding cooling rate and coefficient of performance are revealed. The results obtained in this paper can provide some theoretical guidance for the optimal design of actual regenerative magnetic refrigerator cycle. - Highlights: • Thermodynamic performance of ferromagnetic material is analyzed. • An irreversible regenerative ferromagnetic Ericsson refrigeration cycle is set up. • The thermoeconomic objective function is introduced and optimized. • Impacts of the thermoeconomic and other parameters are discussed.

  7. A Comparison of Different Volumes of Articaine for Inferior Alveolar Nerve Block for Molar Teeth with Symptomatic Irreversible Pulpitis.

    Science.gov (United States)

    Abazarpoor, Ramin; Parirokh, Masoud; Nakhaee, Nouzar; Abbott, Paul V

    2015-09-01

    Achieving anesthesia in mandibular molar teeth with irreversible pulpitis is very difficult. The aim of this study was to compare the efficacy of 1.8 mL and 3.6 mL articaine for an inferior alveolar nerve block (IANB) when treating molars with symptomatic irreversible pulpitis. In a randomized, double-blind clinical trial, 82 first mandibular molar teeth with symptomatic irreversible pulpitis randomly received conventional IANB injection either with 1 (1.8 mL) or 2 cartridges (3.6 mL) of 4% articaine with 1:100,000 epinephrine. The patients recorded their pain before and during access cavity preparation as well as during root canal instrumentation using a Heft-Parker visual analog scale. No or mild pain was considered as successful anesthesia. Data were analyzed by t and chi-square tests. Eighty patients were eligible to participate in this study, which showed that 3.6 mL articaine provided a significantly higher success rate (77.5%) of IANBs compared with 1.8 mL of the same anesthetic solution (27.5%) although neither group had 100% successful anesthesia (P < .001). Increasing the volume of articaine provided a significantly higher success rate of IANBs in mandibular first molar teeth with symptomatic irreversible pulpitis, but it did not result in 100% anesthetic success. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. The Kruskal Count

    OpenAIRE

    Lagarias, Jeffrey C.; Rains, Eric; Vanderbei, Robert J.

    2001-01-01

    The Kruskal Count is a card trick invented by Martin J. Kruskal in which a magician "guesses" a card selected by a subject according to a certain counting procedure. With high probability the magician can correctly "guess" the card. The success of the trick is based on a mathematical principle related to coupling methods for Markov chains. This paper analyzes in detail two simplified variants of the trick and estimates the probability of success. The model predictions are compared with simula...

  9. Study suggests Arctic sea ice loss not irreversible

    Science.gov (United States)

    Balcerak, Ernie

    2011-10-01

    The Arctic has been losing sea ice as Earth's climate warms, and some studies have suggested that the Arctic could reach a tipping point, beyond which ice would not recover even if global temperatures cooled down again. However, a new study by Armour et al. that uses a state-of-the-art atmosphere-ocean global climate model found no evidence of such irreversibility. In their simulations, the researchers increased atmospheric carbon dioxide levels until Arctic sea ice disappeared year-round and then watched what happened as global temperatures were then decreased. They found that sea ice steadily recovered as global temperatures dropped. An implication of this result is that future sea ice loss will occur only as long as global temperatures continue to rise. (Geophysical Research Letters, doi:10.1029/2011GL048739, 2011)

  10. SPERM COUNT DISTRIBUTIONS IN FERTILE MEN

    Science.gov (United States)

    Sperm concentration and count are often used as indicators of environmental impacts on male reproductive health. Existing clinical databases may be biased towards subfertile men with low sperm counts and less is known about expected sperm count distributions in cohorts of fertil...

  11. Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study.

    Science.gov (United States)

    Qudeimat, M A; Alyahya, A; Hasan, A A

    2017-02-01

    To prospectively investigate the clinical and radiographic success rates of pulpotomy in permanent molars with clinical signs and symptoms suggestive of irreversible pulpitis using mineral trioxide aggregate (MTA) as a pulp dressing agent. Sixteen patients with 23 restorable permanent molars exhibiting signs and symptoms indicative of irreversible pulpitis were enrolled. A standardized operative procedure was followed for all participants. All teeth were isolated with a dental dam and caries was removed, and then, pulpotomy performed with a sterile round and/or flame shape diamond burs. Haemostasis was achieved with 5% sodium hypochlorite (NaOCl). A mixture of MTA was placed against the wound, and a moistened cotton pellet was placed over the MTA. Teeth were temporized with a glass-ionomer restoration. Three to ten days later, the interim restoration was removed and setting of MTA was evaluated. Teeth were restored with stainless steel crowns. Follow-up evaluations were scheduled at 3, 6, 12 months and annually thereafter. Descriptive statistics were used to assess outcomes. The age of patients at time of pulpotomy ranged between 7.6 and 13.6 years (mean = 10.7± 1.7 yrs). The majority of teeth (91%) had clinical signs and symptoms consistent with a diagnosis of symptomatic irreversible pulpitis and symptomatic apical periodontitis (78%). The follow-up examination period ranged from 18.9 to 73.6 months. Clinically and radiographically, all pulpotomies were considered successful at the end of the follow-up period. Radiographically, a hard tissue barrier was noticed in 13 (57%) teeth. In children, MTA was associated with high clinical and radiographic success as a pulpotomy agent in permanent teeth with clinical signs and symptoms suggestive of irreversible pulpitis. © 2016 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  12. First-order irreversible thermodynamic approach to a nonsteady RLC circuit as an energy converter

    International Nuclear Information System (INIS)

    Valencia, G; Arias, L A

    2015-01-01

    In this work we show a RLC-circuit as energy converter within the context of first-order irreversible thermodynamics (FOIT). For our analysis, we propose an isothermic model with transient elements and passive elements. With the help of the dynamic equations, the Kirchhoff equations, we found the generalized fluxes and forces of the circuit, the equation system shows symmetry of the cross terms, this property is characteristic of the steady state linear systems, but in this case phenomenological coefficients are function of time. Then, we can use these relations, similar to the linear Onsager relations, to construct the characteristic functions of the RLC energy converter: the power output, efficiency, dissipation and ecological function, and study its energetic performance. The study of performance of the converter is based on two parameters, the coupling parameter and the ''forces ratio'' parameter, in this case as functions of time. We find that the behavior of the non-steady state converter is similar to the behavior of steady state energy converter. We will explain the linear and symmetric behavior of the converter in the frequencies space rather than in the time space. Finally, we establish optimal operation regimes of economic degree of coupling for this energy converter

  13. Effect of irreversible processes on the thermodynamic performance of open-cycle desiccant cooling cycles

    International Nuclear Information System (INIS)

    La, Dong; Li, Yong; Dai, Yanjun; Ge, Tianshu; Wang, Ruzhu

    2013-01-01

    Highlights: ► Effects of irreversible processes on the performance of desiccant cooling cycle are identified. ► The exergy destructions involved are classified by the properties of the individual processes. ► Appropriate indexes for thermodynamic evaluation are proposed based on thermodynamic analyses. - Abstract: Thermodynamic analyses of desiccant cooling cycle usually focus on the overall cycle performance in previous study. In this paper, the effects of the individual irreversible processes in each component on thermodynamic performance are analyzed in detail. The objective of this paper is to reveal the elemental features of the individual components, and to show their effects on the thermodynamic performance of the whole cycle in a fundamental way. Appropriate indexes for thermodynamic evaluation are derived based on the first and second law analyses. A generalized model independent of the connection of components is developed. The results indicate that as the effectiveness of the desiccant wheel increases, the cycle performance is increased principally due to the significant reduction in exergy carried out by exhaust air. The corresponding exergy destruction coefficient of the cycle with moderate performance desiccant wheel is decreased greatly to 3.9%, which is more than 50% lower than that of the cycle with low performance desiccant wheel. The effect of the heat source is similar. As the temperature of the heat source increases from 60 °C to 90 °C, the percentage of exergy destruction raised by exhaust air increases sharply from 5.3% to 21.8%. High heat exchanger effectiveness improves the cycle performance mainly by lowering the irreversibility of the heat exchanger, using less regeneration heat and pre-cooling the process air effectively

  14. Reversible and irreversible magnetization of the Chevrel-phase superconductor PbMo6S8

    International Nuclear Information System (INIS)

    Zheng, D.N.; Ramsbottom, H.D.; Hampshire, D.P.

    1995-01-01

    Magnetic measurements have been carried out on the hot-isostatically-pressed Chevrel-phase superconductor PbMo 6 S 8 at temperatures from 4.2 K to T c and for magnetic fields up to 12 T. The results show that for the PbMo 6 S 8 compound there is a wide magnetically reversible region, between the irreversibility field B irr and the upper critical field B c2 , on the isothermal magnetic hysteresis curves. The B irr (T) line, i.e., the irreversibility line, was found to obey a power-law expression: B irr =B * (1-T/T c ) α with α∼1.5. Magnetic relaxation measurements revealed that the flux-creep effect in the material studied is substantial and is greater than those observed in conventional metallic alloys, but smaller than in high-temperature superconductors. The existence of the irreversibility line and pronounced flux-creep effect in PbMo 6 S 8 is attributed to the short coherence length of the material. From the reversible magnetization data, the values of the penetration depth, the coherence length, and the critical fields are obtained together with the Ginzburg-Landau parameter κ. At 4.2 K, the critical current density J c is 10 9 A m -2 at zero field, and decreases to 2x10 8 A m -2 at 10 T. Pinning force curves measured at different temperatures obey a Kramer-scaling law of the form: F p (=J c xB)∝b 1/2 (1-b) 2 , which indicates that the J c is limited by one predominant flux-pinning mechanism

  15. Parametric analysis of an irreversible proton exchange membrane fuel cell/absorption refrigerator hybrid system

    International Nuclear Information System (INIS)

    Yang, Puqing; Zhang, Houcheng

    2015-01-01

    A hybrid system mainly consisting of a PEMFC (proton exchange membrane fuel cell) and an absorption refrigerator is proposed, where the PEMFC directly converts the chemical energy contained in the hydrogen into electrical and thermal energies, and the thermal energy is transferred to drive the bottoming absorption refrigerator for cooling purpose. By considering the existing irreversible losses in the hybrid system, the operating current density region of the PEMFC permits the absorption refrigerator to exert its function is determined and the analytical expressions for the equivalent power output and efficiency of the hybrid system under different operating conditions are specified. Numerical calculations show that the equivalent maximum power density and the corresponding efficiency of the hybrid system can be respectively increased by 5.3% and 6.8% compared to that of the stand-alone PEMFC. Comprehensive parametric analyses are conducted to reveal the effects of the internal irreversibility of the absorption refrigerator, operating current density, operating temperature and operating pressure of the PEMFC, and some integrated parameters related to the thermodynamic losses on the performance of the hybrid system. The model presented in the paper is more general than previous study, and the results for some special cases can be directly derived from this paper. - Highlights: • A CHP system composed of a PEMFC and an absorption refrigerator is proposed. • Current density region enables the absorption refrigerator to work is determined. • Multiple irreversible losses in the system are analytically characterized. • Maximum power density and corresponding efficiency can be increased by 5.3% and 6.8%. • Effects of some designing and operating parameters on the performance are discussed

  16. The Social Cost of Stochastic and Irreversible Climate Change

    Science.gov (United States)

    Cai, Y.; Judd, K. L.; Lontzek, T.

    2013-12-01

    Many scientists are worried about climate change triggering abrupt and irreversible events leading to significant and long-lasting damages. For example, a rapid release of methane from permafrost may lead to amplified global warming, and global warming may increase the frequency and severity of heavy rainfall or typhoon, destroying large cities and killing numerous people. Some elements of the climate system which might exhibit such a triggering effect are called tipping elements. There is great uncertainty about the impact of anthropogenic carbon and tipping elements on future economic wellbeing. Any rational policy choice must consider the great uncertainty about the magnitude and timing of global warming's impact on economic productivity. While the likelihood of tipping points may be a function of contemporaneous temperature, their effects are long lasting and might be independent of future temperatures. It is assumed that some of these tipping points might occur even in this century, but also that their duration and post-tipping impact are uncertain. A faithful representation of the possibility of tipping points for the calculation of social cost of carbon would require a fully stochastic formulation of irreversibility, and accounting for the deep layer of uncertainties regarding the duration of the tipping process and also its economic impact. We use DSICE, a DSGE extension of the DICE2007 model of William Nordhaus, which incorporates beliefs about the uncertain economic impact of possible climate tipping events and uses empirically plausible parameterizations of Epstein-Zin preferences to represent attitudes towards risk. We find that the uncertainty associated with anthropogenic climate change imply carbon taxes much higher than implied by deterministic models. This analysis indicates that the absence of uncertainty in DICE2007 and similar IAM models may result in substantial understatement of the potential benefits of policies to reduce GHG emissions.

  17. Irreversibility and higher-spin conformal field theory

    CERN Document Server

    Anselmi, D

    2000-01-01

    I discuss the idea that quantum irreversibility is a general principle of nature and a related "conformal hypothesis", stating that all fundamental quantum field theories should be renormalization-group (RG) interpolations between ultraviolet and infrared conformal fixed points. In particular, the Newton constant should be viewed as a low-energy effect of the RG scale. This approach leads naturally to consider higher-spin conformal field theories, which are here classified, as candidate high-energy theories. Bosonic conformal tensors have a positive-definite action, equal to the square of a field strength, and a higher-derivative gauge invariance. The central charges c and a are well defined and positive. I calculate their values and study the operator-product structure. Fermionic theories have no gauge invariance and can be coupled to Abelian and non-Abelian gauge fields in a renormalizable way. At the quantum level, they contribute to the one-loop beta function with the same sign as ordinary matter, admit a...

  18. Bayesian analysis of energy and count rate data for detection of low count rate radioactive sources.

    Science.gov (United States)

    Klumpp, John; Brandl, Alexander

    2015-03-01

    A particle counting and detection system is proposed that searches for elevated count rates in multiple energy regions simultaneously. The system analyzes time-interval data (e.g., time between counts), as this was shown to be a more sensitive technique for detecting low count rate sources compared to analyzing counts per unit interval (Luo et al. 2013). Two distinct versions of the detection system are developed. The first is intended for situations in which the sample is fixed and can be measured for an unlimited amount of time. The second version is intended to detect sources that are physically moving relative to the detector, such as a truck moving past a fixed roadside detector or a waste storage facility under an airplane. In both cases, the detection system is expected to be active indefinitely; i.e., it is an online detection system. Both versions of the multi-energy detection systems are compared to their respective gross count rate detection systems in terms of Type I and Type II error rates and sensitivity.

  19. Counting systems in wavelength and energy dispersive spectrometry: the principle and how to check and to adjust

    International Nuclear Information System (INIS)

    Maurice, Francoise

    1978-03-01

    The purpose of this report is to define the optimum operating conditions of the whole counting systems in wavelength dispersive spectrometry (mostly used in conjunction with electron microprobes) and in energy dispersive spectrometry (more often connected to scanning electron microscopes). For both these techniques, the principle of the detector and its attached counting electronics is recalled; a check list is then given for verifying the qualities of the apparatus and detecting the defects; finally the best operating conditions are defined as essential in an analytical instrument whose reliability has to be perfect [fr

  20. Total bacterial count and somatic cell count in refrigerated raw milk stored in communal tanks

    Directory of Open Access Journals (Sweden)

    Edmar da Costa Alves

    2014-09-01

    Full Text Available The current industry demand for dairy products with extended shelf life has resulted in new challenges for milk quality maintenance. The processing of milk with high bacterial counts compromises the quality and performance of industrial products. The study aimed to evaluate the total bacteria counts (TBC and somatic cell count (SCC in 768 samples of refrigerated raw milk, from 32 communal tanks. Samples were collected in the first quarter of 2010, 2011, 2012 and 2013 and analyzed by the Laboratory of Milk Quality - LQL. Results showed that 62.5%, 37.5%, 15.6% and 27.1% of the means for TBC in 2010, 2011, 2012 and 2013, respectively, were above the values established by legislation. However, we observed a significant reduction in the levels of total bacterial count (TBC in the studied periods. For somatic cell count, 100% of the means indicated values below 600.000 cells/mL, complying with the actual Brazilian legislation. The values found for the somatic cell count suggests the adoption of effective measures for the sanitary control of the herd. However, the results must be considered with caution as it highlights the need for quality improvements of the raw material until it achieves reliable results effectively.

  1. Methematical model of a neutron counting system used for the characteristics control of spontaneously fissioning material

    International Nuclear Information System (INIS)

    Bessis, J.

    1986-09-01

    Methods are described for calculating the probabilities, p(m), of detection of m neutrons, inside a split millisecond counting gate, m varying from zero to some units. At the present stage, these methods suppose the source to be very small. Using the generating function concept, they concern both possible modes of the counting system, for opening gates, i.e.: 1) Trigger pulses randomly with regard to the emitted neutrons, 2) Trigger pulses from the detected neutrons themselves. Computed values are finally compared to the measured ones. This comparison seems to be very favourable, since the respective deviations are often lower than 1 % [fr

  2. Temporal Asymmetry, Entropic Irreversibility, and Finite-Time Thermodynamics: From Parmenides–Einstein Time-Reversal Symmetry to the Heraclitan Entropic Arrow of Time

    Directory of Open Access Journals (Sweden)

    Wassim M. Haddad

    2012-02-01

    Full Text Available In this paper, we combine the two universalisms of thermodynamics and dynamical systems theory to develop a dynamical system formalism for classical thermodynamics. Specifically, using a compartmental dynamical system energy flow model we develop a state-space dynamical system model that captures the key aspects of thermodynamics, including its fundamental laws. In addition, we establish the existence of a unique, continuously differentiable global entropy function for our dynamical system model, and using Lyapunov stability theory we show that the proposed thermodynamic model has finite-time convergent trajectories to Lyapunov stable equilibria determined by the system initial energies. Finally, using the system entropy, we establish the absence of Poincaré recurrence for our thermodynamic model and develop clear and rigorous connections between irreversibility, the second law of thermodynamics, and the entropic arrow of time.

  3. A comprehensive segmentation analysis of crude oil market based on time irreversibility

    Science.gov (United States)

    Xia, Jianan; Shang, Pengjian; Lu, Dan; Yin, Yi

    2016-05-01

    In this paper, we perform a comprehensive entropic segmentation analysis of crude oil future prices from 1983 to 2014 which used the Jensen-Shannon divergence as the statistical distance between segments, and analyze the results from original series S and series begin at 1986 (marked as S∗) to find common segments which have same boundaries. Then we apply time irreversibility analysis of each segment to divide all segments into two groups according to their asymmetry degree. Based on the temporal distribution of the common segments and high asymmetry segments, we figure out that these two types of segments appear alternately and do not overlap basically in daily group, while the common portions are also high asymmetry segments in weekly group. In addition, the temporal distribution of the common segments is fairly close to the time of crises, wars or other events, because the hit from severe events to oil price makes these common segments quite different from their adjacent segments. The common segments can be confirmed in daily group series, or weekly group series due to the large divergence between common segments and their neighbors. While the identification of high asymmetry segments is helpful to know the segments which are not affected badly by the events and can recover to steady states automatically. Finally, we rearrange the segments by merging the connected common segments or high asymmetry segments into a segment, and conjoin the connected segments which are neither common nor high asymmetric.

  4. Rainflow counting revisited

    Energy Technology Data Exchange (ETDEWEB)

    Soeker, H [Deutsches Windenergie-Institut (Germany)

    1996-09-01

    As state of the art method the rainflow counting technique is presently applied everywhere in fatigue analysis. However, the author feels that the potential of the technique is not fully recognized in wind energy industries as it is used, most of the times, as a mere data reduction technique disregarding some of the inherent information of the rainflow counting results. The ideas described in the following aim at exploitation of this information and making it available for use in the design and verification process. (au)

  5. Radon counting statistics - a Monte Carlo investigation

    International Nuclear Information System (INIS)

    Scott, A.G.

    1996-01-01

    Radioactive decay is a Poisson process, and so the Coefficient of Variation (COV) of open-quotes nclose quotes counts of a single nuclide is usually estimated as 1/√n. This is only true if the count duration is much shorter than the half-life of the nuclide. At longer count durations, the COV is smaller than the Poisson estimate. Most radon measurement methods count the alpha decays of 222 Rn, plus the progeny 218 Po and 214 Po, and estimate the 222 Rn activity from the sum of the counts. At long count durations, the chain decay of these nuclides means that every 222 Rn decay must be followed by two other alpha decays. The total number of decays is open-quotes 3Nclose quotes, where N is the number of radon decays, and the true COV of the radon concentration estimate is 1/√(N), √3 larger than the Poisson total count estimate of 1/√3N. Most count periods are comparable to the half lives of the progeny, so the relationship between COV and count time is complex. A Monte-Carlo estimate of the ratio of true COV to Poisson estimate was carried out for a range of count periods from 1 min to 16 h and three common radon measurement methods: liquid scintillation, scintillation cell, and electrostatic precipitation of progeny. The Poisson approximation underestimates COV by less than 20% for count durations of less than 60 min

  6. Irreversible inhibition of RANK expression as a possible mechanism for IL-3 inhibition of RANKL-induced osteoclastogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Khapli, Shruti M.; Tomar, Geetanjali B.; Barhanpurkar, Amruta P.; Gupta, Navita; Yogesha, S.D.; Pote, Satish T. [National Center for Cell Science, University of Pune Campus, Pune 411 007 (India); Wani, Mohan R., E-mail: mohanwani@nccs.res.in [National Center for Cell Science, University of Pune Campus, Pune 411 007 (India)

    2010-09-03

    Research highlights: {yields} IL-3 inhibits receptor activator of NF-{kappa}B ligand (RANKL)-induced osteoclastogenesis. {yields} IL-3 inhibits RANKL-induced JNK activation. {yields} IL-3 down-regulates expression of c-Fos and NFATc1 transcription factors. {yields} IL-3 down-regulates RANK expression posttranscriptionally and irreversibly. {yields} IL-3 inhibits in vivo RANK expression. -- Abstract: IL-3, a cytokine secreted by activated T lymphocytes, stimulates the proliferation, differentiation and survival of pluripotent hematopoietic stem cells. In this study, we investigated the mechanism of inhibitory action of IL-3 on osteoclast differentiation. We show here that IL-3 significantly inhibits receptor activator of NF-{kappa}B (RANK) ligand (RANKL)-induced activation of c-Jun N-terminal kinase (JNK). IL-3 down-regulates expression of c-Fos and nuclear factor of activated T cells (NFATc1) transcription factors. In addition, IL-3 down-regulates RANK expression posttranscriptionally in both purified osteoclast precursors and whole bone marrow cells. Furthermore, the inhibitory effect of IL-3 on RANK expression was irreversible. Interestingly, IL-3 inhibits in vivo RANK expression in mice. Thus, we provide the first evidence that IL-3 irreversibly inhibits RANK expression that results in inhibition of important signaling molecules induced by RANKL.

  7. Irreversible inhibition of RANK expression as a possible mechanism for IL-3 inhibition of RANKL-induced osteoclastogenesis

    International Nuclear Information System (INIS)

    Khapli, Shruti M.; Tomar, Geetanjali B.; Barhanpurkar, Amruta P.; Gupta, Navita; Yogesha, S.D.; Pote, Satish T.; Wani, Mohan R.

    2010-01-01

    Research highlights: → IL-3 inhibits receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis. → IL-3 inhibits RANKL-induced JNK activation. → IL-3 down-regulates expression of c-Fos and NFATc1 transcription factors. → IL-3 down-regulates RANK expression posttranscriptionally and irreversibly. → IL-3 inhibits in vivo RANK expression. -- Abstract: IL-3, a cytokine secreted by activated T lymphocytes, stimulates the proliferation, differentiation and survival of pluripotent hematopoietic stem cells. In this study, we investigated the mechanism of inhibitory action of IL-3 on osteoclast differentiation. We show here that IL-3 significantly inhibits receptor activator of NF-κB (RANK) ligand (RANKL)-induced activation of c-Jun N-terminal kinase (JNK). IL-3 down-regulates expression of c-Fos and nuclear factor of activated T cells (NFATc1) transcription factors. In addition, IL-3 down-regulates RANK expression posttranscriptionally in both purified osteoclast precursors and whole bone marrow cells. Furthermore, the inhibitory effect of IL-3 on RANK expression was irreversible. Interestingly, IL-3 inhibits in vivo RANK expression in mice. Thus, we provide the first evidence that IL-3 irreversibly inhibits RANK expression that results in inhibition of important signaling molecules induced by RANKL.

  8. Anderson localized state as a predissipative state: irreversible emission of thermalized quanta from a dynamically delocalized state.

    Science.gov (United States)

    Yamada, Hiroaki; Ikeda, Kensuke S

    2002-04-01

    It was shown that localization in one-dimensional disordered (quantum) electronic system is destroyed against coherent harmonic perturbations and the delocalized electron exhibits an unlimited diffusive motion [Yamada and Ikeda, Phys. Rev. E 59, 5214 (1999)]. The appearance of diffusion implies that the system has potential for irreversibility and dissipation. In the present paper, we investigate dissipative property of the dynamically delocalized state, and we show that an irreversible quasistationary energy flow indeed appears in the form of a "heat" flow when we couple the system with another dynamical degree of freedom. In the concrete we numerically investigate dissipative properties of a one-dimensional tight-binding electronic system perturbed by time-dependent harmonic forces, by coupling it with a quantum harmonic oscillator or a quantum anharmonic oscillator. It is demonstrated that if the on-site potential is spatially irregular an irreversible energy transfer from the scattered electron to the test oscillator occurs. Moreover, the test oscillator promptly approaches a thermalized state characterized by a well-defined time-dependent temperature. On the contrary, such a relaxation process cannot be observed at all for periodic potential systems. Our system is one of the minimal quantum systems in which a distinct nonequilibrium statistical behavior is self-induced.

  9. Hanford whole body counting manual

    International Nuclear Information System (INIS)

    Palmer, H.E.; Rieksts, G.A.; Lynch, T.P.

    1990-06-01

    This document describes the Hanford Whole Body Counting Program as it is administered by Pacific Northwest Laboratory (PNL) in support of the US Department of Energy--Richland Operations Office (DOE-RL) and its Hanford contractors. Program services include providing in vivo measurements of internally deposited radioactivity in Hanford employees (or visitors). Specific chapters of this manual deal with the following subjects: program operational charter, authority, administration, and practices, including interpreting applicable DOE Orders, regulations, and guidance into criteria for in vivo measurement frequency, etc., for the plant-wide whole body counting services; state-of-the-art facilities and equipment used to provide the best in vivo measurement results possible for the approximately 11,000 measurements made annually; procedures for performing the various in vivo measurements at the Whole Body Counter (WBC) and related facilities including whole body counts; operation and maintenance of counting equipment, quality assurance provisions of the program, WBC data processing functions, statistical aspects of in vivo measurements, and whole body counting records and associated guidance documents. 16 refs., 48 figs., 22 tabs

  10. Platelet Count and Plateletcrit

    African Journals Online (AJOL)

    strated that neonates with late onset sepsis (bacteremia after 3 days of age) had a dramatic increase in MPV and. PDW18. We hypothesize that as the MPV and PDW increase and platelet count and PCT decrease in sick children, intui- tively, the ratio of MPV to PCT; MPV to Platelet count,. PDW to PCT, PDW to platelet ...

  11. The success rate of bupivacaine and lidocaine as anesthetic agents in inferior alveolar nerve block in teeth with irreversible pulpitis without spontaneous pain.

    Science.gov (United States)

    Parirokh, Masoud; Yosefi, Mohammad Hosein; Nakhaee, Nouzar; Abbott, Paul V; Manochehrifar, Hamed

    2015-05-01

    Achieving adequate anesthesia with inferior alveolar nerve blocks (IANB) is of great importance during dental procedures. The aim of the present study was to assess the success rate of two anesthetic agents (bupivacaine and lidocaine) for IANB when treating teeth with irreversible pulpitis. Sixty volunteer male and female patients who required root canal treatment of a mandibular molar due to caries participated in the present study. The inclusion criteria included prolonged pain to thermal stimulus but no spontaneous pain. The patients were randomly allocated to receive either 2% lidocaine with 1:80,000 epinephrine or 0.5% bupivacaine with 1:200,000 epinephrine as an IANB injection. The sensitivity of the teeth to a cold test as well as the amount of pain during access cavity preparation and root canal instrumentation were recorded. Results were statistically analyzed with the Chi-Square and Fischer's exact tests. At the final step, fifty-nine patients were included in the study. The success rate for bupivacaine and lidocaine groups were 20.0% and 24.1%, respectively. There was no significant difference between the two groups at any stage of the treatment procedure. There was no difference in success rates of anesthesia when bupivacaine and lidocaine were used for IANB injections to treat mandibular molar teeth with irreversible pulpitis. Neither agent was able to completely anesthetize the teeth effectively. Therefore, practitioners should be prepared to administer supplemental anesthesia to overcome pain during root canal treatment.

  12. Problems of saturation of the excitation and creation of irreversible changes in solid after laser irradiation

    International Nuclear Information System (INIS)

    Sakhnyuk, L.A.; Trokhimchuck, P.P.

    2009-01-01

    The problem of modeling of processes of the irreversible interaction light and solid is discussed. This problem is connected with the processes of the saturation the excitation of respective scattering centers. The possible cascades of these processes are analyzed. The correlation between nonequilibrium and irreversible phenomena are analyzed. Two-dimensional sphalerite lattice of InSb was used for the kinetic modeling of the hierarchic processes of saturation of the excitation respective chemical bonds. The cascade characteristics of these processes were estimated for the cylindrical form of 'zone of energy scattering' of photon. The comparative analyses these results with results, which were received with the help straight method and method the spherical form of 'zone of energy scattering' of photon, is represented too. The good concordance of experimental and theoretical data was received. (authors)

  13. An Adaptive Smoother for Counting Measurements

    International Nuclear Information System (INIS)

    Kondrasovs Vladimir; Coulon Romain; Normand Stephane

    2013-06-01

    Counting measurements associated with nuclear instruments are tricky to carry out due to the stochastic process of the radioactivity. Indeed events counting have to be processed and filtered in order to display a stable count rate value and to allow variations monitoring in the measured activity. Smoothers (as the moving average) are adjusted by a time constant defined as a compromise between stability and response time. A new approach has been developed and consists in improving the response time while maintaining count rate stability. It uses the combination of a smoother together with a detection filter. A memory of counting data is processed to calculate several count rate estimates using several integration times. These estimates are then sorted into the memory from short to long integration times. A measurement position, in terms of integration time, is then chosen into this memory after a detection test. An inhomogeneity into the Poisson counting process is detected by comparison between current position estimate and the other estimates contained into the memory in respect with the associated statistical variance calculated with homogeneous assumption. The measurement position (historical time) and the ability to forget an obsolete data or to keep in memory a useful data are managed using the detection test result. The proposed smoother is then an adaptive and a learning algorithm allowing an optimization of the response time while maintaining measurement counting stability and converging efficiently to the best counting estimate after an effective change in activity. This algorithm has also the specificity to be low recursive and thus easily embedded into DSP electronics based on FPGA or micro-controllers meeting 'real life' time requirements. (authors)

  14. High Resolution Gamma Ray Spectroscopy at MHz Counting Rates With LaBr3 Scintillators for Fusion Plasma Applications

    Science.gov (United States)

    Nocente, M.; Tardocchi, M.; Olariu, A.; Olariu, S.; Pereira, R. C.; Chugunov, I. N.; Fernandes, A.; Gin, D. B.; Grosso, G.; Kiptily, V. G.; Neto, A.; Shevelev, A. E.; Silva, M.; Sousa, J.; Gorini, G.

    2013-04-01

    High resolution γ-ray spectroscopy measurements at MHz counting rates were carried out at nuclear accelerators, combining a LaBr 3(Ce) detector with dedicated hardware and software solutions based on digitization and off-line analysis. Spectra were measured at counting rates up to 4 MHz, with little or no degradation of the energy resolution, adopting a pile up rejection algorithm. The reported results represent a step forward towards the final goal of high resolution γ-ray spectroscopy measurements on a burning plasma device.

  15. 59th Medical Wing Clinical Research Division Clinical Investigations Program Posters (Count: 2)

    Science.gov (United States)

    2017-05-08

    Investigations Program Posters (Count: 2) presented at/published to Graduate School Faculty Development and Research Symposium, Gateway Club, JBSA...copy of your abstract, paper. poster and other supporting documentation. 5. Save and forward, via email, the processing form and all supporting...you a final letter of approval or disapproval. g, Once your manuscript, poster or presentation has been approved for a one-lime public release, you may

  16. Counting probe

    International Nuclear Information System (INIS)

    Matsumoto, Haruya; Kaya, Nobuyuki; Yuasa, Kazuhiro; Hayashi, Tomoaki

    1976-01-01

    Electron counting method has been devised and experimented for the purpose of measuring electron temperature and density, the most fundamental quantities to represent plasma conditions. Electron counting is a method to count the electrons in plasma directly by equipping a probe with the secondary electron multiplier. It has three advantages of adjustable sensitivity, high sensitivity of the secondary electron multiplier, and directional property. Sensitivity adjustment is performed by changing the size of collecting hole (pin hole) on the incident front of the multiplier. The probe is usable as a direct reading thermometer of electron temperature because it requires to collect very small amount of electrons, thus it doesn't disturb the surrounding plasma, and the narrow sweep width of the probe voltage is enough. Therefore it can measure anisotropy more sensitively than a Langmuir probe, and it can be used for very low density plasma. Though many problems remain on anisotropy, computer simulation has been carried out. Also it is planned to provide a Helmholtz coil in the vacuum chamber to eliminate the effect of earth magnetic field. In practical experiments, the measurement with a Langmuir probe and an emission probe mounted to the movable structure, the comparison with the results obtained in reverse magnetic field by using a Helmholtz coil, and the measurement of ionic sound wave are scheduled. (Wakatsuki, Y.)

  17. A mind you can count on: validating breath counting as a behavioral measure of mindfulness

    Directory of Open Access Journals (Sweden)

    Daniel B Levinson

    2014-10-01

    Full Text Available Mindfulness practice of present moment awareness promises many benefits, but has eluded rigorous behavioral measurement. To date, research has relied on self-reported mindfulness or heterogeneous mindfulness trainings to infer skillful mindfulness practice and its effects. In four independent studies with over 400 total participants, we present the first construct validation of a behavioral measure of mindfulness, breath counting. We found it was reliable, correlated with self-reported mindfulness, differentiated long-term meditators from age-matched controls, and was distinct from sustained attention and working memory measures. In addition, we employed breath counting to test the nomological network of mindfulness. As theorized, we found skill in breath counting associated with more meta-awareness, less mind wandering, better mood, and greater nonattachment (i.e. less attentional capture by distractors formerly paired with reward. We also found in a randomized online training study that 4 weeks of breath counting training improved mindfulness and decreased mind wandering relative to working memory training and no training controls. Together, these findings provide the first evidence for breath counting as a behavioral measure of mindfulness.

  18. Principles of correlation counting

    International Nuclear Information System (INIS)

    Mueller, J.W.

    1975-01-01

    A review is given of the various applications which have been made of correlation techniques in the field of nuclear physics, in particular for absolute counting. Whereas in most cases the usual coincidence method will be preferable for its simplicity, correlation counting may be the only possible approach in such cases where the two radiations of the cascade cannot be well separated or when there is a longliving intermediate state. The measurement of half-lives and of count rates of spurious pulses is also briefly discussed. The various experimental situations lead to different ways the correlation method is best applied (covariance technique with one or with two detectors, application of correlation functions, etc.). Formulae are given for some simple model cases, neglecting dead-time corrections

  19. Evaluation of the Gow-Gates and Vazirani-Akinosi techniques in patients with symptomatic irreversible pulpitis: a prospective randomized study.

    Science.gov (United States)

    Click, Vivian; Drum, Melissa; Reader, Al; Nusstein, John; Beck, Mike

    2015-01-01

    Few studies have evaluated the effectiveness of the Gow-Gates and Vazirani-Akinosi techniques in patients presenting with symptomatic irreversible pulpitis. Therefore, the purpose of this prospective, randomized study was to evaluate the anesthetic efficacy of the Gow-Gates and Vazirani-Akinosi techniques using 3.6 mL 2% lidocaine with 1:100,000 epinephrine in mandibular posterior teeth in patients presenting with symptomatic irreversible pulpitis. One hundred twenty-five emergency patients diagnosed with symptomatic irreversible pulpitis randomly received either a Gow-Gates or Vazirani-Akinosi injection using 3.6 mL 2% lidocaine with 1:100,000 epinephrine to block the inferior alveolar nerve before endodontic access. Subjective lip numbness was recorded. Pulpal anesthetic success of the injection was defined as no pain or mild pain upon endodontic access and instrumentation as measured on a visual analog scale. Subjective lip numbness was obtained 92% of the time with the Gow-Gates technique and 63% of the time with the Vazirani-Akinosi technique. The difference was statistically significant (P = .0001). For the patients achieving lip numbness, successful pulpal anesthesia was obtained 35% of the time with the Gow-Gates technique and 16% of the time with the Vazirani-Akinosi technique. The difference was statistically significant (P = .0381). We concluded that for patients who achieved lip numbness neither the Gow-Gates technique nor the Vazirani-Akinosi technique provided adequate pulpal anesthesia for mandibular posterior teeth in patients presenting with symptomatic irreversible pulpitis. Both injections would require supplemental anesthesia. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  20. Irreversible Sorption of Contaminants During Ferrihydrite Transformation

    International Nuclear Information System (INIS)

    Anderson, H.L.; Arthur, S.E.; Brady, P.V.; Cygan, R.T.; Nagy, K.L.; Westrich, H.R.

    1999-01-01

    A better understanding of the fraction of contaminants irreversibly sorbed by minerals is necessary to effectively quantify bioavailability. Ferrihydrite, a poorly crystalline iron oxide, is a natural sink for sorbed contaminants. Contaminants may be sorbed/occluded as ferrihydrite precipitates in natural waters or as it ages and transforms to more crystalline iron oxides such as goethite or hematite. Laboratory studies indicate that Cd, Co, Cr, Cu, Ni, Np, Pb, Sr, U, and Zn are irreversibly sorbed to some extent during the aging and transformation of synthetic ferrihydrite. Barium, Ra and Sr are known to sorb on ferrihydrite in the pH range of 6 to 10 and sorb more strongly at pH values above its zero point of charge (pH> 8). We will review recent literature on metal retardation, including our laboratory and modeling investigation of Ba (as an analogue for Ra) and Sr adsorption/resorption, during ferrihydrite transformation to more crystalline iron oxides. Four ferrihydrite suspensions were aged at pH 12 and 50 C with or without Ba in 0.01 M KN03 for 68 h or in 0.17 M KN03 for 3424 h. Two ferrihydrite suspensions were aged with and without Sr at pH 8 in 0.1 M KN03 at 70C. Barium or Sr sorption, or resorption, was measured by periodically centrifuging suspension subsamples, filtering, and analyzing the filtrate for Ba or Sr. Solid subsamples were extracted with 0.2 M ammonium oxalate (pH 3 in the dark) and with 6 M HCl to determine the Fe and Ba or Sr attributed to ferrihydrite (or adsorbed on the goethite/hematite stiace) and the total Fe and Ba or Sr content, respectively. Barium or Sr occluded in goethite/hematite was determined by the difference between the total Ba or Sr and the oxalate extractable Ba or Sr. The percent transformation of ferrihydrite to goethite/hematite was estimated from the ratio of oxalate and HC1 extractable Fe. All Ba was retained in the precipitates for at least 20 h. Resorption of Ba reached a maximum of 7 to 8% of the Ba2+ added for

  1. Delta count-rate monitoring system

    International Nuclear Information System (INIS)

    Van Etten, D.; Olsen, W.A.

    1985-01-01

    A need for a more effective way to rapidly search for gamma-ray contamination over large areas led to the design and construction of a very sensitive gamma detection system. The delta count-rate monitoring system was installed in a four-wheel-drive van instrumented for environmental surveillance and accident response. The system consists of four main sections: (1) two scintillation detectors, (2) high-voltage power supply amplifier and single-channel analyzer, (3) delta count-rate monitor, and (4) count-rate meter and recorder. The van's 6.5-kW generator powers the standard nuclear instrument modular design system. The two detectors are mounted in the rear corners of the van and can be run singly or jointly. A solid-state bar-graph count-rate meter mounted on the dashboard can be read easily by both the driver and passenger. A solid-state strip chart recorder shows trends and provides a permanent record of the data. An audible alarm is sounded at the delta monitor and at the dashboard count-rate meter if a detected radiation level exceeds the set background level by a predetermined amount

  2. DC KIDS COUNT e-Databook Indicators

    Science.gov (United States)

    DC Action for Children, 2012

    2012-01-01

    This report presents indicators that are included in DC Action for Children's 2012 KIDS COUNT e-databook, their definitions and sources and the rationale for their selection. The indicators for DC KIDS COUNT represent a mix of traditional KIDS COUNT indicators of child well-being, such as the number of children living in poverty, and indicators of…

  3. A Derivation of a Microscopic Entropy and Time Irreversibility From the Discreteness of Time

    Directory of Open Access Journals (Sweden)

    Roland Riek

    2014-06-01

    Full Text Available The basic microsopic physical laws are time reversible. In contrast, the second law of thermodynamics, which is a macroscopic physical representation of the world, is able to describe irreversible processes in an isolated system through the change of entropy ΔS > 0. It is the attempt of the present manuscript to bridge the microscopic physical world with its macrosocpic one with an alternative approach than the statistical mechanics theory of Gibbs and Boltzmann. It is proposed that time is discrete with constant step size. Its consequence is the presence of time irreversibility at the microscopic level if the present force is of complex nature (F(r ≠ const. In order to compare this discrete time irreversible mechamics (for simplicity a “classical”, single particle in a one dimensional space is selected with its classical Newton analog, time reversibility is reintroduced by scaling the time steps for any given time step n by the variable sn leading to the Nosé-Hoover Lagrangian. The corresponding Nos´e-Hoover Hamiltonian comprises a term Ndf kB T ln sn (kB the Boltzmann constant, T the temperature, and Ndf the number of degrees of freedom which is defined as the microscopic entropy Sn at time point n multiplied by T. Upon ensemble averaging this microscopic entropy Sn in equilibrium for a system which does not have fast changing forces approximates its macroscopic counterpart known from thermodynamics. The presented derivation with the resulting analogy between the ensemble averaged microscopic entropy and its thermodynamic analog suggests that the original description of the entropy by Boltzmann and Gibbs is just an ensemble averaging of the time scaling variable sn which is in equilibrium close to 1, but that the entropy

  4. In vivo counting of uranium

    International Nuclear Information System (INIS)

    Palmer, H.E.

    1985-03-01

    A state-of-the-art radiation detector system consisting of six individually mounted intrinsic germanium planar detectors, each 20 cm 2 by 13 mm thick, mounted together such that the angle of the whole system can be changed to match the slope of the chest of the person being counted, is described. The sensitivity of the system for counting uranium and plutonium in vivo and the precedures used in calibrating the system are also described. Some results of counts done on uranium mill workers are presented. 15 figs., 2 tabs

  5. Irreversible Aspects of Continuum Mechanics and Transfer of Physical Characteristics in Moving Fluids : Symposia

    CERN Document Server

    Sedov, L

    1968-01-01

    At its meeting on April 23, 1965 in Paris the Bureau of IUTAM decided to have a Symposium on the Irreversible Aspects of Continaum Mechanics held in June 1966 in Vienna. In addition, a Symposium on the Transfer of Physical Characteristics in Moving Fluids which, orig­ inally, had been scheduled to take place in Stockholm was rescheduled to be held in Vienna immediately following the Symposium on the Irre­ versible Aspects of Continuum Mechanics. It was felt that the subjects of the two symposia were so closely related that participants should be given an opportunity to attend both. Both decisions were unanimously approved by the members of the General Assembly of IUTAM. Prof. H. PARKUS, Vienna, was appointed Chairman of the Symposium on the Irreversible Aspects, and Prof. L. I. SEDOV, Moscow, was appointed Chairman of the Symposium on the Transfer of Physical Characteristics, with Prof. P ARKUS being re­ sponsible for the local organization of both symposia. In accordance with the policy set forth by IUTAM...

  6. Irreversible Change of the Pore Structure of ZIF-8 in Carbon Dioxide Capture with Water Coexistence

    DEFF Research Database (Denmark)

    Liu, Huang; Guo, Ping; Regueira Muñiz, Teresa

    2016-01-01

    The performance of zeolitic imidazolate framework 8 (ZIF-8) for CO2 capture under three different conditions (wetted ZIF-8, ZIF-8/water slurry, and ZIF-8/water-glycol slurry) was systemically investigated. This investigation included the study of the pore structure stability of ZIF-8 by using X......-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, and Raman detection technologies. Our results show that the CO2 adsorption ability of ZIF-8 could be substantially increased under the existence of liquid water. However, the structure characterization of the recovered ZIF-8...... showed an irreversible change of its framework, which occurs during the CO2 capture process. It was found that there is an irreversible chemical reaction among ZIF-8, water, and CO2, which creates both zinc carbonate (or zinc carbonate hydroxides) and single 2-methylimidazole crystals, and therefore...

  7. Alpha scintillation radon counting

    International Nuclear Information System (INIS)

    Lucas, H.F. Jr.

    1977-01-01

    Radon counting chambers which utilize the alpha-scintillation properties of silver activated zinc sulfide are simple to construct, have a high efficiency, and, with proper design, may be relatively insensitive to variations in the pressure or purity of the counter filling. Chambers which were constructed from glass, metal, or plastic in a wide variety of shapes and sizes were evaluated for the accuracy and the precision of the radon counting. The principles affecting the alpha-scintillation radon counting chamber design and an analytic system suitable for a large scale study of the 222 Rn and 226 Ra content of either air or other environmental samples are described. Particular note is taken of those factors which affect the accuracy and the precision of the method for monitoring radioactivity around uranium mines

  8. Structural transition models for a class or irreversible aggregates

    International Nuclear Information System (INIS)

    Canessa, E.

    1995-02-01

    A progress report on two recent theoretical approaches proposed to understand the physics of irreversible fractal aggregates showing up a structural transition from a rather dense to a more multibranched growth is presented. In the first approach the transition is understood by solving the Poisson equation on a squared lattice. The second approach is based on the discretization of the Biharmonic equation. Within these models the transition appears when the growth velocity at the fractal surface presents a minimum. The effects of the surrounding medium and geometrical constraints for the seed particles are considered. By using the optical diffraction method, the structural transition is further characterized by a decrease in the fractal dimension for this peculiar class of aggregates. (author). 17 refs, 4 figs

  9. In vitro antimicrobial activity of irreversible hydrocolloid impressions against 12 oral microorganisms

    OpenAIRE

    Casemiro,Luciana Assirati; Pires-de-Souza,Fernanda de Carvalho Panzeri; Panzeri,Heitor; Martins,Carlos Henrique Gomes; Ito,Isabel Yoko

    2007-01-01

    This study evaluated in vitro the antimicrobial activity of irreversible hydrocolloids (one containing an antimicrobial agent) prepared with water or with a 0.2% chlorhexidine digluconate solution against 12 strains of the oral microbiota. Twenty specimens (0.5 x 1.0 cm) for each group (1. Jeltrate mixed with water; 2. Jeltrate mixed with 0.2% chlorhexidine digluconate solution; 3. Greengel mixed with water; 4. Greengel mixed with 0.2% chlorhexidine digluconate solution) were prepared under s...

  10. Equivalence of truncated count mixture distributions and mixtures of truncated count distributions.

    Science.gov (United States)

    Böhning, Dankmar; Kuhnert, Ronny

    2006-12-01

    This article is about modeling count data with zero truncation. A parametric count density family is considered. The truncated mixture of densities from this family is different from the mixture of truncated densities from the same family. Whereas the former model is more natural to formulate and to interpret, the latter model is theoretically easier to treat. It is shown that for any mixing distribution leading to a truncated mixture, a (usually different) mixing distribution can be found so that the associated mixture of truncated densities equals the truncated mixture, and vice versa. This implies that the likelihood surfaces for both situations agree, and in this sense both models are equivalent. Zero-truncated count data models are used frequently in the capture-recapture setting to estimate population size, and it can be shown that the two Horvitz-Thompson estimators, associated with the two models, agree. In particular, it is possible to achieve strong results for mixtures of truncated Poisson densities, including reliable, global construction of the unique NPMLE (nonparametric maximum likelihood estimator) of the mixing distribution, implying a unique estimator for the population size. The benefit of these results lies in the fact that it is valid to work with the mixture of truncated count densities, which is less appealing for the practitioner but theoretically easier. Mixtures of truncated count densities form a convex linear model, for which a developed theory exists, including global maximum likelihood theory as well as algorithmic approaches. Once the problem has been solved in this class, it might readily be transformed back to the original problem by means of an explicitly given mapping. Applications of these ideas are given, particularly in the case of the truncated Poisson family.

  11. Selective effect of irreversible electroporation on parenchyma of the pancreas and its vascular structures - an in vivo experiment on a porcine model

    Directory of Open Access Journals (Sweden)

    Roman Svatoň

    2016-01-01

    Full Text Available Irreversible electroporation is a local, non-thermal ablation method, where short electrical pulses of high voltage lead to changes in cell membrane permeability and cell death. Recent experimental studies have shown that it does not lead to damage of blood vessels, nerves, bile duct or ureters. The aim of our experimental study was to evaluate the negative effect of irreversible electroporation regarding damage to the vascular wall and porcine pancreatic tissue. Irreversible electroporation of the pancreas was performed in 6 pigs after medial laparotomy. Irreversible electroporation was applied to each pig to the splenic lobe of the pancreas in order to assess damage to the pancreatic tissue and to the duodenal lobe of the pancreas to assess damage to the vascular structure of the pancreatic tissue. Higher ablation electric intensity (minimum 500 V/cm – maximum 1,750 V/cm, step 250 V/cm in 90 μs pulses was utilized on each pig. After 7 days, macroscopic and microscopic evaluations of en bloc resected specimen (pancreas with duodenum were performed. During 7 post-ablation days, no deaths or clinical worsening occurred in any of the pigs. Necrotic changes in the pancreatic tissue were recorded at an electric intensity of 750 V/cm. Changes in the outer layers of the wall of the arteries and veins occurred at 1,000 V/cm. Transmural vascular wall damage was not recorded in any case. Irreversible electroporation allows for relatively efficient cell death in the target tissues. Our independent experimental work confirms the safety of this method towards vascular structures located in the ablation zone.

  12. Determination of Li, B, and F by rapid instrumental neutron activation analysis using beta-particle counting

    International Nuclear Information System (INIS)

    Schmidt, J.O.; Palgaard, L.; Gwozdz, R.; Belhage, L.O.

    1984-01-01

    For the simultaneous determination of Li, B, and F, the application of rapid instrument neutron activation analysis was studied using 1.5s of irradiation and β-particle counting of 8 Li, 12 B, and 20 F. The fast transfer facility, Mach-1, the counting equipment, a 4-channel multiplexer, and a time-base controller are discussed. Further, the technique of simultaneous decay curve analysis of three successive decays is presented and quality control by residual analysis is demonstrated. Finally, analytical results are presented of the NBS-environmental standards Coal-1632a and Coal-1635, and of three BCR-coals intended as references materials

  13. Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.

    Science.gov (United States)

    Bultema, Kristy; Fowler, Sara; Drum, Melissa; Reader, Al; Nusstein, John; Beck, Mike

    2016-12-01

    In the treatment of patients with symptomatic irreversible pulpitis, endodontic debridement is a predictable method to relieve pain. However, there are clinical situations in which emergency care cannot be provided immediately. An unexplored treatment option in these cases may be the use of a long-acting anesthetic to reduce pain in untreated irreversible pulpitis. Some medical studies have shown potential for infiltrations of liposomal bupivacaine (Exparel; Pacira Pharmaceuticals, San Diego, CA) to prolong pain relief and reduce opioid use postoperatively. The Food and Drug Administration has approved Exparel only for infiltrations; therefore, the purpose of this study was to compare an infiltration of liposomal bupivacaine versus bupivacaine for pain control in untreated, symptomatic irreversible pulpitis. Ninety-five emergency patients received 2% lidocaine with 1:100,000 epinephrine via infiltration or an inferior alveolar nerve block to relieve their initial presenting pain. Patients then randomly received either 4 mL liposomal bupivacaine (13.3 mg/mL) or 4 mL 0.5% bupivacaine with 1:200,000 epinephrine by infiltration. Patients received a diary for the day of the appointment and 3 days postinjection to record soft tissue numbness, pain levels, and analgesic (non-narcotic and narcotic) use. No significant differences (P pulpitis. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  14. Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molar.

    Science.gov (United States)

    Sampaio, Roberta Moura; Carnaval, Talita Girio; Lanfredi, Camila Bernardeli; Horliana, Anna Carolina Ratto Tempestini; Rocha, Rodney Garcia; Tortamano, Isabel Peixoto

    2012-05-01

    The purpose of this study was to compare the anesthetic efficacy of 0.5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth. Seventy volunteers, patients with irreversible pulpitis admitted to the Emergency Center of the School of Dentistry at the University of São Paulo, randomly received a conventional inferior alveolar nerve block containing 3.6 mL of either 0.5% bupivacaine with 1:200,000 epinephrine or 2% lidocaine with 1:100,000 epinephrine. During the subsequent pulpectomy, we recorded the patients' subjective assessments of lip anesthesia, the absence/presence of pulpal anesthesia through electric pulp stimulation, and the absence/presence of pain through a verbal analog scale. All patients reported lip anesthesia after the application of either inferior alveolar nerve block. By measuring pulpal anesthesia success with the pulp tester, lidocaine had a higher success rate (42.9%) than bupivacaine (20%). For patients reporting none or mild pain during pulpectomy, the success rate of bupivacaine was 80% and lidocaine was 62.9%. There were only statistically significant differences to the success of pulpal anesthesia. Neither of the solutions resulted in an effective pain control during irreversible pulpitis treatments of mandibular molars. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  15. Blood Count Tests: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish WBC count (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Blood Count Tests ... WBC count Show More Show Less Related Health Topics Bleeding Disorders Blood Laboratory Tests National Institutes of ...

  16. Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients.

    Science.gov (United States)

    Karon, Brad S; Tolan, Nicole V; Wockenfus, Amy M; Block, Darci R; Baumann, Nikola A; Bryant, Sandra C; Clements, Casey M

    2017-11-01

    Lactate, white blood cell (WBC) and neutrophil count, procalcitonin and immature granulocyte (IG) count were compared for the prediction of sepsis, and severe sepsis or septic shock, in patients presenting to the emergency department (ED). We prospectively enrolled 501 ED patients with a sepsis panel ordered for suspicion of sepsis. WBC, neutrophil, and IG counts were measured on a Sysmex XT-2000i analyzer. Lactate was measured by i-STAT, and procalcitonin by Brahms Kryptor. We classified patients as having sepsis using a simplification of the 1992 consensus conference sepsis definitions. Patients with sepsis were further classified as having severe sepsis or septic shock using established criteria. Univariate receiver operating characteristic (ROC) analysis was performed to determine odds ratio (OR), area under the ROC curve (AUC), and sensitivity/specificity at optimal cut-off for prediction of sepsis (vs. no sepsis), and prediction of severe sepsis or septic shock (vs. no sepsis). There were 267 patients without sepsis; and 234 with sepsis, including 35 patients with severe sepsis or septic shock. Lactate had the highest OR (1.44, 95th% CI 1.20-1.73) for the prediction of sepsis; while WBC, neutrophil count and percent (neutrophil/WBC) had OR>1.00 (psepsis or septic shock, with an odds ratio (95th% CI) of 2.70 (2.02-3.61) and AUC 0.89 (0.82-0.96). Traditional biomarkers (lactate, WBC, neutrophil count, procalcitonin, IG) have limited utility in the prediction of sepsis. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  17. Serum Copper Level Significantly Influences Platelet Count, Lymphocyte Count and Mean Cell Hemoglobin in Sickle Cell Anemia

    Directory of Open Access Journals (Sweden)

    Okocha Chide

    2015-12-01

    Full Text Available Background Changes in serum micro nutrients levels affect a number of critically important metabolic processes; these could potentially influence blood counts and ultimately disease presentation in patients with sickle cell anemia (SCA. Objectives To evaluate the influence of serum micro-nutrients levels; zinc, copper, selenium and magnesium on blood counts in steady state SCA patients. Methods A cross sectional study that involved 28 steady state adult SCA subjects. Seven milliliters (mls of blood was collected; 3 mls was for hemoglobin electrophoresis and full blood count determination while 4 mls was for measurement of serum micro nutrients levels, by the atomic absorption spectrophotometry. Correlation between serum micro-nutrient levels and blood counts was done by the Pearson’s linear regression. Ethical approval was obtained from the institutional review board and each participant gave informed consent. All data was analyzed by SPSS software version 20. Results There was a significant correlation between serum copper levels and mean cell hemoglobin (MCH, platelet and lymphocyte counts (r = 0.418; P = 0.02, r = -0.376; P = 0.04 and r = -0.383; P = 0.04, respectively. There were no significant correlations between serum levels of other micro nutrients (selenium, zinc and magnesium and blood counts. Conclusions Copper influences blood count in SCA patients probably by inducing red cell haemolysis, oxidant tissue damage and stimulating the immune system.

  18. Use of cadmium in solution in the EL 4 reactor moderator irreversible fixing of cadmium on the metallic surfaces; Utilisation du cadmium en solution dans le moderateur du reacteur EL 4 - fixation irreversible du cadmium sur les surfaces metalliques

    Energy Technology Data Exchange (ETDEWEB)

    Croix, O; Paoli, O; Lecomte, J; Dolle, L; Gallic, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    In the framework of research into the poisoning of the EL-4 reactor by cadmium sulphate, measurements have been made by two different methods of the residual amounts of cadmium liable to be fixed irreversibly on the surfaces in contact with the heavy water. A marked influence of the pH has been noticed. The mechanism of the irreversible fixing is compatible with the hypothesis of an ion-exchange in the surface oxide layer. In a sufficiently wide range of pH the cadmium thus fixed causes very little residual poisoning. The stability of the cadmium sulphate solutions is however rather low in the conditions of poisoning. (authors) [French] Dans le cadre des etudes sur l'empoisonnement du reacteur EL-4 par le sulfate de cadmium, les quantites residuelles de cadmium susceptibles de se fixer irreversiblement sur les parois que mouillerait l'eau lourde, ont ete mesurees experimentalement par deux methodes differentes. On observe une influence nette du pH. Le mecanisme de la fixation irreversible est compatible avec l'hypothese d'un echange d'ions dans la pellicule d'oxyde superficielle. Dans des limites suffisamment larges de pH, la cadmium ainsi fixe n'occasionne pas d'empoisonnement residuel important. La stabilite des solutions de sulfate de cadmium dans les conditions de l'empoisonnement est cependant mediocre. (auteurs)

  19. PENGUKURAN KADAR NATRIUM ALGINAT DARI ALGA COKELAT SPESIES Sargassum sp. SEBAGAI BAHAN DASAR PEMBUATAN BAHAN CETAK KEDOKTERAN GIGI (IRREVERSIBLE HYDROCOLLOID/DENTAL IMPRESSION MATERIAL)

    OpenAIRE

    MUTMAINNAH SUNAR, SITI

    2016-01-01

    2015 Pengukuran Kadar Natrium Alginate dari Alga Cokelat Spesies Sargassum sp. sebagai Bahan Dasar Pembuatan Bahan Cetak Kedokteran Gigi (Irreversible Hydrocolloid/Dental Impression Material) Siti Mutmainnah Sunar Abstrak Latar belakang : Irreversible hydrocolloid merupakan bahan cetak yang relatif sering digunakan di bidang kedokteran gigi. Namun, bahan baku dari bahan cetak ini masih diimpor dari luar negeri. Natrium alginate sebagai bahan baku masih menggunakan ekstraksi alga c...

  20. Angle-dependent reversible and irreversible magnetic torque in single-crystalline Y2Ba4Cu8O16

    International Nuclear Information System (INIS)

    Zech, D.; Rossel, C.; Lesne, L.; Keller, H.; Lee, S.L.; Karpinski, J.

    1996-01-01

    A systematic study of the angle-dependent reversible and irreversible magnetic torque in single-crystalline Y 2 Ba 4 Cu 8 O 16 is presented. The high purity of the crystals allows us to show some intrinsic pinning properties of vortices due to the layered crystal structure. The irreversible component of the torque, which is unusually small, exhibits a peculiar angular dependence: It is minimal as the magnetic field B is applied along the ab plane and displays a pronounced maximum at finite angles, reminiscent of the open-quote open-quote fishtail close-quote close-quote effect. The unusual shape of the irreversible torque is attributed to the pinning of the vortex core, which becomes discontinuous below the two- to three-dimensional (2D-3D) crossover temperature. Another property shown by the angle-dependent torque is the lock-in of the vortex lines between the CuO 2 layers for B parallel to the ab plane. Applying the anisotropic 3D London model to fit the reversible torque data, we derive the in-plane London penetration depth λ ab =143 nm, the coherence length ξ ab =1.9 nm, and the effective mass anisotropy ratio γ=12.3 for Y 2 Ba 4 Cu 8 O 16 . copyright 1996 The American Physical Society

  1. Irreversible energy flow in forced Vlasov dynamics

    KAUST Repository

    Plunk, Gabriel G.; Parker, Joseph T.

    2014-01-01

    © EDP Sciences, Società Italiana di Fisica, Springer-Verlag. The recent paper of Plunk [G.G. Plunk, Phys. Plasmas 20, 032304 (2013)] considered the forced linear Vlasov equation as a model for the quasi-steady state of a single stable plasma wavenumber interacting with a bath of turbulent fluctuations. This approach gives some insight into possible energy flows without solving for nonlinear dynamics. The central result of the present work is that the forced linear Vlasov equation exhibits asymptotically zero (irreversible) dissipation to all orders under a detuning of the forcing frequency and the characteristic frequency associated with particle streaming. We first prove this by direct calculation, tracking energy flow in terms of certain exact conservation laws of the linear (collisionless) Vlasov equation. Then we analyze the steady-state solutions in detail using a weakly collisional Hermite-moment formulation, and compare with numerical solution. This leads to a detailed description of the Hermite energy spectrum, and a proof of no dissipation at all orders, complementing the collisionless Vlasov result.

  2. Irreversible energy flow in forced Vlasov dynamics

    KAUST Repository

    Plunk, Gabriel G.

    2014-10-01

    © EDP Sciences, Società Italiana di Fisica, Springer-Verlag. The recent paper of Plunk [G.G. Plunk, Phys. Plasmas 20, 032304 (2013)] considered the forced linear Vlasov equation as a model for the quasi-steady state of a single stable plasma wavenumber interacting with a bath of turbulent fluctuations. This approach gives some insight into possible energy flows without solving for nonlinear dynamics. The central result of the present work is that the forced linear Vlasov equation exhibits asymptotically zero (irreversible) dissipation to all orders under a detuning of the forcing frequency and the characteristic frequency associated with particle streaming. We first prove this by direct calculation, tracking energy flow in terms of certain exact conservation laws of the linear (collisionless) Vlasov equation. Then we analyze the steady-state solutions in detail using a weakly collisional Hermite-moment formulation, and compare with numerical solution. This leads to a detailed description of the Hermite energy spectrum, and a proof of no dissipation at all orders, complementing the collisionless Vlasov result.

  3. Correction for decay during counting in gamma spectrometry

    International Nuclear Information System (INIS)

    Nir-El, Y.

    2013-01-01

    A basic result in gamma spectrometry is the count rate of a relevant peak. Correction for decay during counting and expressing the count rate at the beginning of the measurement can be done by a multiplicative factor that is derived from integrating the count rate over time. The counting time substituted in this factor must be the live time, whereas the use of the real-time is an error that underestimates the count rate by about the dead-time (DT) (in percentage). This error of underestimation of the count rate is corroborated in the measurement of a nuclide with a high DT. The present methodology is not applicable in systems that include a zero DT correction function. (authors)

  4. Interpretation of galaxy counts

    International Nuclear Information System (INIS)

    Tinsely, B.M.

    1980-01-01

    New models are presented for the interpretation of recent counts of galaxies to 24th magnitude, and predictions are shown to 28th magnitude for future comparison with data from the Space Telescope. The results supersede earlier, more schematic models by the author. Tyson and Jarvis found in their counts a ''local'' density enhancement at 17th magnitude, on comparison with the earlier models; the excess is no longer significant when a more realistic mixture of galaxy colors is used. Bruzual and Kron's conclusion that Kron's counts show evidence for evolution at faint magnitudes is confirmed, and it is predicted that some 23d magnitude galaxies have redshifts greater than unity. These may include spheroidal systems, elliptical galaxies, and the bulges of early-type spirals and S0's, seen during their primeval rapid star formation

  5. The effect of growth temperature on the irreversibility line of MPMG YBCO bulk with Y2O3 layer

    Science.gov (United States)

    Kurnaz, Sedat; Çakır, Bakiye; Aydıner, Alev

    2017-07-01

    In this study, three kinds of YBCO samples which are named Y1040, Y1050 and Y1060 were fabricated by Melt-Powder-Melt-Growth (MPMG) method without a seed crystal. Samples seem to be single crystal. The compacted powders were located on a crucible with a buffer layer of Y2O3 to avoid liquid to spread on the furnace plate and also to support crystal growth. YBCO samples were investigated by magnetoresistivity (ρ-T) and magnetization (M-T) measurements in dc magnetic fields (parallel to c-axis) up to 5 T. Irreversibility fields (Hirr) and upper critical fields (Hc2) were obtained using 10% and 90% criteria of the normal state resistivity value from ρ-T curves. M-T measurements were carried out using the zero field cooling (ZFC) and field cooling (FC) processes to get irreversible temperature (Tirr). Fitting of the irreversibility line results to giant flux creep and vortex glass models were discussed. The results were found to be consistent with the results of the samples fabricated using a seed crystal. At the fabrication of MPMG YBCO, optimized temperature for crystal growth was determined to be around 1050-1060 °C.

  6. Total lymphocyte count as a substitute to cd4 count in management of hiv infected individuals in resource limited society

    International Nuclear Information System (INIS)

    Daud, M.Y.; Qazi, R.A.

    2015-01-01

    Pakistan is a resource limited society and gold standard parameters to monitor HIV disease activity are very costly. The objective of the study was to evaluate total lymphocyte count (TLC) as a surrogate to CD4 count to monitor disease activity in HIV/AIDS in resource limited society. Methods: This cross sectional study was carried out at HIV/AIDS treatment centre, Pakistan Institute of Medical Sciences (PIMS), Islamabad. A total of seven hundred and seventy four (774) HIV positive patients were enrolled in this study, and their CD4 count and total lymphocyte count were checked to find any correlation between the two by using Spearman ranked correlation coefficient. Results: The mean CD4 count was (434.30 ± 269.23), with minimum CD4 count of (9.00), and maximum of (1974.00). The mean total lymphocyte count (TLC) was (6764.0052 ± 2364.02) with minimum TLC (1200.00) and maximum TLC was (20200.00). Using the Pearson's correlation (r) there was a significant and positive correlation between TLC and CD4 count. (r2=0.127 and p=0.000) at 0.01 level. Conclusion: Our study showed a significant positive correlation between CD4 count and total lymphocyte count (TLC), so TLC can be used as a marker of disease activity in HIV infected patients. (author)

  7. Evaluation of biogenic amines and microbial counts throughout the ripening of goat cheeses from pasteurized and raw milk.

    Science.gov (United States)

    Novella-Rodríguez, Sonia; Veciana-Nogués, M Teresa; Roig-Sagués, Artur X; Trujillo-Mesa, Antonio J; Vidal-Carou, M Carmen

    2004-05-01

    The effect of the hygienic quality of milk on changes in microbial counts and biogenic amine content was evaluated during ripening of goat cheeses manufactured from pasteurized and raw milks at 1, 14, 30, 60 and 90 d. The original milk, rennet, curd and whey were also included in the study. The pH, salt content and extent of proteolysis in the cheese were also evaluated. Spermidine and spermine were the main amines in raw milk, while they were minor amines in cheeses. Other amines increased markedly during ripening, tyramine being the main amine in cheese made from raw milk and cadaverine and putrescine in those produced from pasteurized milk. Enterobacteriaceae counts decreased during ripening whereas those of lactic acid bacteria increased, especially lactobacilli and enterococci. Cheese made from raw milk showed higher microbial counts during ripening than those made from pasteurized milk, especially for Enterobacteriaceae and enterococci, counts being 2 or 3 log units higher. Raw milk cheese showed remarkably higher biogenic amines compared with pasteurized milk cheeses. Therefore, pasteurization of milk causes a decrease in final biogenic amine content of cheese as a result of the reduction of its microbial counts.

  8. Wall heat flux influence on the thermodynamic optimisation of irreversibilities of a circulating fluidised bed combustor

    CSIR Research Space (South Africa)

    Baloyi, J

    2016-07-01

    Full Text Available . The irreversibilities generated were arrived at by computing the entropy generation rates due to the combustion and frictional pressure drop processes. For the combustor where the wall condition was changed from adiabatic to negative heat flux (that is heat leaving...

  9. A counting-card circuit based on PCI bus

    International Nuclear Information System (INIS)

    Shi Jing; Li Yong; Chinese Academy of Sciences, Lanzhou; Su Hong; Dong Chengfu; Li Xiaogang; Ma Xiaoli

    2004-01-01

    A counting-card circuit based on PCI bus that we developed recently used for advanced personal computer will be introduced in this paper briefly. The maximum count capacity of this counting-card is 10 9 -1, ranging from 0 to 999 999 999, the maximum counting time range, 1 x 10 6 s, can be set in 1 cycle, the maximum counting rate is 20 MHz for positive input. (authors)

  10. EXPERIMENTAL AND THEORETICAL INVESTIGATIONS OF NEW POWER CYCLES AND ADVANCED FALLING FILM HEAT EXCHANGERS; FINAL

    International Nuclear Information System (INIS)

    Arsalan Razani; Kwang J. Kim

    2001-01-01

    The final report for the DOE/UNM grant number DE-FG26-98FT40148 discusses the accomplishments of both the theoretical analysis of advanced power cycles and experimental investigation of advanced falling film heat exchangers. This final report also includes the progress report for the third year (period of October 1, 2000 to September 30, 2001). Four new cycles were studied and two cycles were analyzed in detail based on the second law of thermodynamics. The first cycle uses a triple combined cycle, which consists of a topping cycle (Brayton/gas), an intermediate cycle (Rankine/steam), and a bottoming cycle (Rankine/ammonia). This cycle can produce high efficiency and reduces the irreversibility of the Heat Recovery Steam Generator (HRSC) of conventional combined power cycles. The effect of important system parameters on the irreversibility distribution of all components in the cycle under reasonable practical constraints was evaluated. The second cycle is a combined cycle, which consists of a topping cycle (Brayton/gas) and a bottoming cycle (Rankine/ammonia) with integrated compressor inlet air cooling. This innovative cycle can produce high power and efficiency. This cycle is also analyzed and optimized based on the second the second law to obtain the irreversibility distribution of all components in the cycle. The results of the studies have been published in peer reviewed journals and ASME conference proceeding. Experimental investigation of advanced falling film heat exchangers was conducted to find effective additives for steam condensation. Four additives have been selected and tested in a horizontal tube steam condensation facility. It has been observed that heat transfer additives have been shown to be an effective way to increase the efficiency of conventional tube bundle condenser heat exchangers. This increased condensation rate is due to the creation of a disturbance in the liquid condensate surround the film. The heat transfer through such a film has

  11. The success rate of bupivacaine and lidocaine as anesthetic agents in inferior alveolar nerve block in teeth with irreversible pulpitis without spontaneous pain

    Directory of Open Access Journals (Sweden)

    Masoud Parirokh

    2015-05-01

    Full Text Available Objectives Achieving adequate anesthesia with inferior alveolar nerve blocks (IANB is of great importance during dental procedures. The aim of the present study was to assess the success rate of two anesthetic agents (bupivacaine and lidocaine for IANB when treating teeth with irreversible pulpitis. Materials and Methods Sixty volunteer male and female patients who required root canal treatment of a mandibular molar due to caries participated in the present study. The inclusion criteria included prolonged pain to thermal stimulus but no spontaneous pain. The patients were randomly allocated to receive either 2% lidocaine with 1:80,000 epinephrine or 0.5% bupivacaine with 1:200,000 epinephrine as an IANB injection. The sensitivity of the teeth to a cold test as well as the amount of pain during access cavity preparation and root canal instrumentation were recorded. Results were statistically analyzed with the Chi-Square and Fischer's exact tests. Results At the final step, fifty-nine patients were included in the study. The success rate for bupivacaine and lidocaine groups were 20.0% and 24.1%, respectively. There was no significant difference between the two groups at any stage of the treatment procedure. Conclusions There was no difference in success rates of anesthesia when bupivacaine and lidocaine were used for IANB injections to treat mandibular molar teeth with irreversible pulpitis. Neither agent was able to completely anesthetize the teeth effectively. Therefore, practitioners should be prepared to administer supplemental anesthesia to overcome pain during root canal treatment.

  12. The success rate of bupivacaine and lidocaine as anesthetic agents in inferior alveolar nerve block in teeth with irreversible pulpitis without spontaneous pain

    Science.gov (United States)

    Yosefi, Mohammad Hosein; Nakhaee, Nouzar

    2015-01-01

    Objectives Achieving adequate anesthesia with inferior alveolar nerve blocks (IANB) is of great importance during dental procedures. The aim of the present study was to assess the success rate of two anesthetic agents (bupivacaine and lidocaine) for IANB when treating teeth with irreversible pulpitis. Materials and Methods Sixty volunteer male and female patients who required root canal treatment of a mandibular molar due to caries participated in the present study. The inclusion criteria included prolonged pain to thermal stimulus but no spontaneous pain. The patients were randomly allocated to receive either 2% lidocaine with 1:80,000 epinephrine or 0.5% bupivacaine with 1:200,000 epinephrine as an IANB injection. The sensitivity of the teeth to a cold test as well as the amount of pain during access cavity preparation and root canal instrumentation were recorded. Results were statistically analyzed with the Chi-Square and Fischer's exact tests. Results At the final step, fifty-nine patients were included in the study. The success rate for bupivacaine and lidocaine groups were 20.0% and 24.1%, respectively. There was no significant difference between the two groups at any stage of the treatment procedure. Conclusions There was no difference in success rates of anesthesia when bupivacaine and lidocaine were used for IANB injections to treat mandibular molar teeth with irreversible pulpitis. Neither agent was able to completely anesthetize the teeth effectively. Therefore, practitioners should be prepared to administer supplemental anesthesia to overcome pain during root canal treatment. PMID:25984478

  13. Reference analysis of the signal + background model in counting experiments

    Science.gov (United States)

    Casadei, D.

    2012-01-01

    The model representing two independent Poisson processes, labelled as ``signal'' and ``background'' and both contributing additively to the total number of counted events, is considered from a Bayesian point of view. This is a widely used model for the searches of rare or exotic events in presence of a background source, as for example in the searches performed by high-energy physics experiments. In the assumption of prior knowledge about the background yield, a reference prior is obtained for the signal alone and its properties are studied. Finally, the properties of the full solution, the marginal reference posterior, are illustrated with few examples.

  14. TU-FG-209-03: Exploring the Maximum Count Rate Capabilities of Photon Counting Arrays Based On Polycrystalline Silicon

    Energy Technology Data Exchange (ETDEWEB)

    Liang, A K; Koniczek, M; Antonuk, L E; El-Mohri, Y; Zhao, Q [University of Michigan, Ann Arbor, MI (United States)

    2016-06-15

    Purpose: Photon counting arrays (PCAs) offer several advantages over conventional, fluence-integrating x-ray imagers, such as improved contrast by means of energy windowing. For that reason, we are exploring the feasibility and performance of PCA pixel circuitry based on polycrystalline silicon. This material, unlike the crystalline silicon commonly used in photon counting detectors, lends itself toward the economic manufacture of radiation tolerant, monolithic large area (e.g., ∼43×43 cm2) devices. In this presentation, exploration of maximum count rate, a critical performance parameter for such devices, is reported. Methods: Count rate performance for a variety of pixel circuit designs was explored through detailed circuit simulations over a wide range of parameters (including pixel pitch and operating conditions) with the additional goal of preserving good energy resolution. The count rate simulations assume input events corresponding to a 72 kVp x-ray spectrum with 20 mm Al filtration interacting with a CZT detector at various input flux rates. Output count rates are determined at various photon energy threshold levels, and the percentage of counts lost (e.g., due to deadtime or pile-up) is calculated from the ratio of output to input counts. The energy resolution simulations involve thermal and flicker noise originating from each circuit element in a design. Results: Circuit designs compatible with pixel pitches ranging from 250 to 1000 µm that allow count rates over a megacount per second per pixel appear feasible. Such rates are expected to be suitable for radiographic and fluoroscopic imaging. Results for the analog front-end circuitry of the pixels show that acceptable energy resolution can also be achieved. Conclusion: PCAs created using polycrystalline silicon have the potential to offer monolithic large-area detectors with count rate performance comparable to those of crystalline silicon detectors. Further improvement through detailed circuit

  15. Recursive algorithms for phylogenetic tree counting.

    Science.gov (United States)

    Gavryushkina, Alexandra; Welch, David; Drummond, Alexei J

    2013-10-28

    In Bayesian phylogenetic inference we are interested in distributions over a space of trees. The number of trees in a tree space is an important characteristic of the space and is useful for specifying prior distributions. When all samples come from the same time point and no prior information available on divergence times, the tree counting problem is easy. However, when fossil evidence is used in the inference to constrain the tree or data are sampled serially, new tree spaces arise and counting the number of trees is more difficult. We describe an algorithm that is polynomial in the number of sampled individuals for counting of resolutions of a constraint tree assuming that the number of constraints is fixed. We generalise this algorithm to counting resolutions of a fully ranked constraint tree. We describe a quadratic algorithm for counting the number of possible fully ranked trees on n sampled individuals. We introduce a new type of tree, called a fully ranked tree with sampled ancestors, and describe a cubic time algorithm for counting the number of such trees on n sampled individuals. These algorithms should be employed for Bayesian Markov chain Monte Carlo inference when fossil data are included or data are serially sampled.

  16. Exergy analysis on the irreversibility of rotary air preheater in thermal power plant

    International Nuclear Information System (INIS)

    Wang Hongyue; Zhao Lingling; Zhou Qiangtai; Xu Zhigao; Kim, Hyung Taek

    2008-01-01

    Energy recovery devices can have a substantial impact on process efficiency and their relevance to the problem of conservation of energy resources is generally recognized to be beyond dispute. One type of such a device, which is commonly used in thermal power plants and air conditioning systems, is the rotary air preheater. A major disadvantage of the rotary air preheater is that there is an unavoidable leakage due to carry over and pressure difference. There are gas streams involved in the heat transfer and mixing processes. There are also irreversibilities, or exergy destruction, due to mixing, pressure losses and temperature gradients. Therefore, the purpose of this research paper is based from the second law of thermodynamics, which is to build up the relationship between the efficiency of the thermal power plant and the total process of irreversibility in the rotary air preheater using exergy analysis. For this, the effects of the variation of the principal design parameters on the rotary air preheater efficiency, the exergy efficiency, and the efficiency of the thermal power plant are examined by changing a number of parameters of rotary air preheater. Furthermore, some conclusions are reached and recommendations are made so as to give insight on designing some optimal parameters

  17. Photon-counting image sensors

    CERN Document Server

    Teranishi, Nobukazu; Theuwissen, Albert; Stoppa, David; Charbon, Edoardo

    2017-01-01

    The field of photon-counting image sensors is advancing rapidly with the development of various solid-state image sensor technologies including single photon avalanche detectors (SPADs) and deep-sub-electron read noise CMOS image sensor pixels. This foundational platform technology will enable opportunities for new imaging modalities and instrumentation for science and industry, as well as new consumer applications. Papers discussing various photon-counting image sensor technologies and selected new applications are presented in this all-invited Special Issue.

  18. Relativistic thermodynamics of irreversible processes I. Heat conduction, diffusion, viscous flow and chemical reactions; formal part

    NARCIS (Netherlands)

    Kluitenberg, G.A.; Groot, S.R. de; Mazur, P.

    1953-01-01

    The relativistic thermodynamics of irreversible processes is developed for an isotropic mixture in which heat conduction, diffusion, viscous flow, chemical reactions and their cross-phenomena may occur. The four-vectors, representing the relative flows of matter, are defined in such a way that, in

  19. Irreversible traps, their influence on the embrittlement of high strength steel

    International Nuclear Information System (INIS)

    Mariano, I; Mansilla, G

    2012-01-01

    Hydrogen (H) can be trapped in lattice defects such as vacancies, dislocations, grain boundaries and interfaces between the matrix and precipitates. The effect on the mechanical properties depends on factors inherent in materials such as the activation energy of irreversible traps (H trapped in Network Places) and its sensitivity to embrittlement. Differential scanning calorimetry (DSC) allows the study of those processes in which enthalpy variation occurs. The purpose is to record the difference in enthalpy change that occurs in the sample as a function of temperature or time. This work represents a study of H embrittlement of high strength steel resulfurized

  20. Platelet counting using the Coulter electronic counter.

    Science.gov (United States)

    Eggleton, M J; Sharp, A A

    1963-03-01

    A method for counting platelets in dilutions of platelet-rich plasm using the Coulter electronic counter is described.(1) The results obtained show that such platelet counts are at least as accurate as the best methods of visual counting. The various technical difficulties encountered are discussed.

  1. Automated uranium analysis by delayed-neutron counting

    International Nuclear Information System (INIS)

    Kunzendorf, H.; Loevborg, L.; Christiansen, E.M.

    1980-10-01

    Automated uranium analysis by fission-induced delayed-neutron counting is described. A short description is given of the instrumentation including transfer system, process control, irradiation and counting sites, and computer operations. Characteristic parameters of the facility (sample preparations, background, and standards) are discussed. A sensitivity of 817 +- 22 counts per 10 -6 g U is found using irradiation, delay, and counting times of 20 s, 5 s, and 10 s, respectively. Presicion is generally less than 1% for normal geological samples. Critical level and detection limits for 7.5 g samples are 8 and 16 ppb, respectively. The importance of some physical and elemental interferences are outlined. Dead-time corrections of measured count rates are necessary and a polynomical expression is used for count rates up to 10 5 . The presence of rare earth elements is regarded as the most important elemental interference. A typical application is given and other areas of application are described. (auther)

  2. A quantum analogy for the linear thermodynamics of irreversible processes

    International Nuclear Information System (INIS)

    Ibanez-Mengual, J.A.; Tejerina-Garcia, A.F.

    1981-01-01

    In this paper, a model for the transport through a liquid junction of two solutions of the same components, based on quantum-mechanical considerations, is established. A small energy difference, compared with the molecules' energy, among the molecules placed at both sides of the junction is assumed to exist. The liquid junction is assimilated to a potential barrier, getting the material flow from the transmission coefficient of the barrier, when the energy difference is caused by a temperature gradient, a concentration gradient, or both gradients acting together. In all cases, equations formally identical to those of the thermodynamics of irreversible processes are obtained. In the last case, the heat flow is also determined. (author)

  3. Count rate effect in proportional counters

    International Nuclear Information System (INIS)

    Bednarek, B.

    1980-01-01

    A new concept is presented explaining changes in spectrometric parameters of proportional counters which occur due to varying count rate. The basic feature of this concept is that the gas gain of the counter remains constant in a wide range of count rate and that the decrease in the pulse amplitude and the detorioration of the energy resolution observed are the results of changes in the shape of original current pulses generated in the active volume of the counter. In order to confirm the validity of this statement, measurements of the gas amplification factor have been made in a wide count rate range. It is shown that above a certain critical value the gas gain depends on both the operating voltage and the count rate. (author)

  4. The usefulness of computed tomography in distinguishing between asthma with irreversible air-flow limitation and pulmonary emphysema

    International Nuclear Information System (INIS)

    Taniguchi, Hiroyuki; Ogawa, Kenji; Nakajima, Yoko; Amano, Masao; Kondo, Yasuhiro; Matsumoto, Kohei; Yokoyama, Sigeki; Matsubara, Kazuhito

    1988-01-01

    Chronic asthma may develop irreversible air-flow limitation and in this circumstance, it is clinically difficult to distinguish between asthma and pulmonary emphysema. Recently, it has been reported that computed tomography (CT) may assist in detecting changes in the lung specific for emphysema. We examined patients who suffered from asthma before the age of 45 which led to irreversible air-flow limitation (BA group; n = 17, mean age = 65.9) and patients with pulmonary emphysema (CPE group; n = 19, mean age = 69.8). Pulmonary function testing and CT were performed on all patients. In assessment of CT, areas of low attenuation and vascular disruption were considered to be suggestive of emphysema, and the Emphysema Score (ES) was calculated according to the method of Bergin et al. There was no significant difference in FEV1.0, % FEV1.0, % FEV1.0/FVC, % RV and RV/TLC between the BA group and the CPE group. In contrast, there was a significant decrease in the % DLco in CPE group compared with that of the BA group (p < 0.001). The ES in total lung was 54.9 ± 18.6 % in the CPE group and 7.8 ± 11.0 % in BA group (p < 0.001). There was a significant correlation between the % DLco and the ES in the CPE group (p < 0.01). We conclude that the CT is useful in distinguishing between asthma with irreversible air-flow limitation and pulmonary emphysema. (author)

  5. Nitric oxide-related species-induced protein oxidation: reversible, irreversible, and protective effects on enzyme function of papain.

    Science.gov (United States)

    Väänänen, Antti J; Kankuri, Esko; Rauhala, Pekka

    2005-04-15

    Protein oxidation, irreversible modification, and inactivation may play key roles in various neurodegenerative disorders. Therefore, we studied the effects of the potentially in vivo occurring nitric oxide-related species on two different markers of protein oxidation: protein carbonyl generation on bovine serum albumine (BSA) and loss of activity of a cysteine-dependent protease, papain, in vitro by using Angeli's salt, papanonoate, SIN-1, and S-nitrosoglutathione (GSNO) as donors of nitroxyl, nitric oxide, peroxynitrite, and nitrosonium ions, respectively. Angeli's salt, SIN-1, and papanonoate (0-1000 microM) all generated a concentration-dependent increase in carbonyl formation on BSA (107, 60, and 45%, respectively). GSNO did not affect carbonyl formation. Papain was inhibited by Angeli's salt, SIN-1, papanonoate, and GSNO with IC50 values of 0.62, 2.3, 54, and 80 microM, respectively. Angeli's salt (3.16 microM)-induced papain inactivation was only partially reversible, while the effects of GSNO (316 microM) and papanonoate (316 microM) were reversible upon addition of excess DTT. The Angeli's salt-mediated DTT-irreversible inhibition of papain was prevented by GSNO or papanonoate pretreatment, hypothetically through mixed disulfide formation or S-nitrosylation of the catalytically critical thiol group of papain. These results, for the first time, compare the generation of carbonyls in proteins by Angeli's salt, papanonoate, and SIN-1. Furthermore, these results suggest that S-nitrosothiols may have a novel function in protecting critical thiols from irreversible oxidative damage.

  6. Performance evaluation and optimization of fluidized bed boiler in ethanol plant using irreversibility analysis

    Directory of Open Access Journals (Sweden)

    Nugroho Agung Pambudi

    2017-09-01

    Full Text Available This research aims to evaluate the performance of a fluidized bed boiler in an ethanol production plant through exergy and irreversibility analysis. The study also includes the optimization of the pre-heater and the deaerator in order to improve the system efficiency. Operational data from the ethanol production plant was collected between 2015 and early 2016. The total exergy derived from the fuel was determined to be 7783 kJ/s, while the exergy efficiency of the system was found to be 26.19%, with 2214 kJ/s used in steam production, while 71.55% was lost to component irreversibility and waste heat from the pre-heater. The exergy efficiencies of individual components of the system such as the boiler, deaerator, and pre-heater were found to be 25.82%, 40.13%, and 2.617%, respectively, with the pre-heater having the lowest efficiency. Thus, the pre-heater has the highest potential to significantly improve the efficiency of the boiler system. The optimization of the pre-heater shows that a rise in temperature in the outlet of the pre-heater positively affects the exergy efficiency of the deaerator.

  7. Resonance ionization spectroscopy: Counting noble gas atoms

    International Nuclear Information System (INIS)

    Hurst, G.S.; Payne, M.G.; Chen, C.H.; Willis, R.D.; Lehmann, B.E.; Kramer, S.D.

    1981-01-01

    The purpose of this paper is to describe new work on the counting of noble gas atoms, using lasers for the selective ionization and detectors for counting individual particles (electrons or positive ions). When positive ions are counted, various kinds of mass analyzers (magnetic, quadrupole, or time-of-flight) can be incorporated to provide A selectivity. We show that a variety of interesting and important applications can be made with atom-counting techniques which are both atomic number (Z) and mass number (A) selective. (orig./FKS)

  8. Counting and Surveying Homeless Youth: Recommendations from YouthCount 2.0!, a Community-Academic Partnership.

    Science.gov (United States)

    Narendorf, Sarah C; Santa Maria, Diane M; Ha, Yoonsook; Cooper, Jenna; Schieszler, Christine

    2016-12-01

    Communities across the United States are increasing efforts to find and count homeless youth. This paper presents findings and lessons learned from a community/academic partnership to count homeless youth and conduct an in depth research survey focused on the health needs of this population. Over a 4 week recruitment period, 632 youth were counted and 420 surveyed. Methodological successes included an extended counting period, broader inclusion criteria to capture those in unstable housing, use of student volunteers in health training programs, recruiting from magnet events for high risk youth, and partnering with community agencies to disseminate findings. Strategies that did not facilitate recruitment included respondent driven sampling, street canvassing beyond known hotspots, and having community agencies lead data collection. Surveying was successful in gathering data on reasons for homelessness, history in public systems of care, mental health history and needs, sexual risk behaviors, health status, and substance use. Youth were successfully surveyed across housing types including shelters or transitional housing (n = 205), those in unstable housing such as doubled up with friends or acquaintances (n = 75), and those who were literally on the streets or living in a place not meant for human habitation (n = 140). Most youth completed the self-report survey and provided detailed information about risk behaviors. Recommendations to combine research data collection with counting are presented.

  9. Improving the counting efficiency in time-correlated single photon counting experiments by dead-time optimization

    Energy Technology Data Exchange (ETDEWEB)

    Peronio, P.; Acconcia, G.; Rech, I.; Ghioni, M. [Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy)

    2015-11-15

    Time-Correlated Single Photon Counting (TCSPC) has been long recognized as the most sensitive method for fluorescence lifetime measurements, but often requiring “long” data acquisition times. This drawback is related to the limited counting capability of the TCSPC technique, due to pile-up and counting loss effects. In recent years, multi-module TCSPC systems have been introduced to overcome this issue. Splitting the light into several detectors connected to independent TCSPC modules proportionally increases the counting capability. Of course, multi-module operation also increases the system cost and can cause space and power supply problems. In this paper, we propose an alternative approach based on a new detector and processing electronics designed to reduce the overall system dead time, thus enabling efficient photon collection at high excitation rate. We present a fast active quenching circuit for single-photon avalanche diodes which features a minimum dead time of 12.4 ns. We also introduce a new Time-to-Amplitude Converter (TAC) able to attain extra-short dead time thanks to the combination of a scalable array of monolithically integrated TACs and a sequential router. The fast TAC (F-TAC) makes it possible to operate the system towards the upper limit of detector count rate capability (∼80 Mcps) with reduced pile-up losses, addressing one of the historic criticisms of TCSPC. Preliminary measurements on the F-TAC are presented and discussed.

  10. The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teeth.

    Directory of Open Access Journals (Sweden)

    Hisanori Eba

    Full Text Available Matrix metalloproteinases (MMPs are involved in extracellular matrix degradation and the modulation of cell behavior. These proteinases have also been implicated in tissue repair and regeneration. Our previous studies have demonstrated that MMP-3 elicits stimulatory effects on the proliferation and the migration of endothelial cells as well as anti-apoptotic effects on these cells in vitro. In addition, we found that MMP-3 enhanced the regeneration of lost pulp tissue in a rat incisor pulp injury model. However, continuously erupting rodent incisors exhibit significantly different pulp organization compared with mature erupted teeth. Therefore, we have further extended these studies using a canine irreversible pulpitis model to investigate the effects of MMP-3. In this study, the crowns of the canine mature premolars were removed and the pulp tissues were amputated. The amputated pulp tissues remained exposed for 24 or 72 hours to induce mild or severe irreversible pulpitis, respectively, followed by sealing of the cavities. In both models, the whole pulp tissues became necrotic by day 14. In this mild pulpitis model, the regeneration of pulp tissue with vasculature and nerves was observed until 14 days after sealing with MMP-3, followed by extracellular matrix formation in the regenerated pulp tissues until day 28. The treatment with MMP-3 resulted in a decrease in the number of macrophage and antigen-presenting cells and a significant inhibition of IL-6 expression on day 3. The inhibition of MMP-3 activity abolished these anti-inflammatory effects. Immunofluorescence staining demonstrated that MMP-3 was involved in the modification of serum-derived hyaluronan-associated proteins and hyaluronan (SHAP-HA complexes possibly through the degradation of versican. These results demonstrate that MMP-3 can act as an anti-inflammatory agent and suggest that MMP-3 might represent a useful therapy for the treatment of mild irreversible pulpitis.

  11. The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teeth.

    Science.gov (United States)

    Eba, Hisanori; Murasawa, Yusuke; Iohara, Koichiro; Isogai, Zenzo; Nakamura, Hiroshi; Nakamura, Hiroyuki; Nakashima, Misako

    2012-01-01

    Matrix metalloproteinases (MMPs) are involved in extracellular matrix degradation and the modulation of cell behavior. These proteinases have also been implicated in tissue repair and regeneration. Our previous studies have demonstrated that MMP-3 elicits stimulatory effects on the proliferation and the migration of endothelial cells as well as anti-apoptotic effects on these cells in vitro. In addition, we found that MMP-3 enhanced the regeneration of lost pulp tissue in a rat incisor pulp injury model. However, continuously erupting rodent incisors exhibit significantly different pulp organization compared with mature erupted teeth. Therefore, we have further extended these studies using a canine irreversible pulpitis model to investigate the effects of MMP-3. In this study, the crowns of the canine mature premolars were removed and the pulp tissues were amputated. The amputated pulp tissues remained exposed for 24 or 72 hours to induce mild or severe irreversible pulpitis, respectively, followed by sealing of the cavities. In both models, the whole pulp tissues became necrotic by day 14. In this mild pulpitis model, the regeneration of pulp tissue with vasculature and nerves was observed until 14 days after sealing with MMP-3, followed by extracellular matrix formation in the regenerated pulp tissues until day 28. The treatment with MMP-3 resulted in a decrease in the number of macrophage and antigen-presenting cells and a significant inhibition of IL-6 expression on day 3. The inhibition of MMP-3 activity abolished these anti-inflammatory effects. Immunofluorescence staining demonstrated that MMP-3 was involved in the modification of serum-derived hyaluronan-associated proteins and hyaluronan (SHAP-HA) complexes possibly through the degradation of versican. These results demonstrate that MMP-3 can act as an anti-inflammatory agent and suggest that MMP-3 might represent a useful therapy for the treatment of mild irreversible pulpitis.

  12. Kinetics of irreversible thermal decomposition of dissociating nitrogen dioxide with nitrogen oxide or oxygen additions

    International Nuclear Information System (INIS)

    Gvozdev, A.A.

    1987-01-01

    The effect of NO or O 2 admixtures on kinetics of the irreversible thermal decomposition of nitrogen dioxide at temperatures 460-520 deg C and pressures 4-7 MPa has been studied. It follows from experimental data that the rate of N 2 O 4 formation reduces with the increase of partial pressure of oxygen or decrease of partial pressure of nitrogen oxide. The same regularity is seen for the rate of nitrogen formation. The rate constants of N 2 O formation in dissociating nitrogen tetroxide with oxygen or nitrogen oxide additions agree satisfactorily with previously published results, obtained in stoichiometric mixtures. The appreciable discrepancy at 520 deg C is bind with considerable degree of nitrogen oxide transformation which constitutes approximately 14%. It is determined that the kinetics of formation of the products of irreversible N 2 O and N 2 decomposition in stoichiometric and non-stoichiometric 2NO 2 ↔ 2NO+O 2 mixtures is described by identical 3NO → N 2 O+NO 2 and N 2 O+NO → N 2 +NO 2 reactions

  13. CalCOFI Larvae Counts Positive Tows

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fish larvae counts and standardized counts for eggs captured in CalCOFI icthyoplankton nets (primarily vertical [Calvet or Pairovet], oblique [bongo or ring nets],...

  14. Set of counts by scintillations for atmospheric samplings

    International Nuclear Information System (INIS)

    Appriou, D.; Doury, A.

    1962-01-01

    The author reports the development of a scintillation-based counting assembly with the following characteristics: a photo-multiplier with a wide photo-cathode, a thin plastic scintillator for the counting of beta + alpha (and possibility of mounting an alpha scintillator), a relatively small own motion with respect to activities to be counted, a weakly varying efficiency. The authors discuss the counting objective, present equipment tests (counter, proportional amplifier and pre-amplifier, input drawer). They describe the apparatus operation, discuss the selection of scintillators, report the study of the own movement (electron-based background noise, total background noise, background noise reduction), discuss counts (influence of the external source, sensitivity to alpha radiations, counting homogeneity, minimum detectable activity) and efficiencies

  15. The effect of pouring time on the dimensional accuracy of casts made from different irreversible hydrocolloid impression materials

    Directory of Open Access Journals (Sweden)

    Supneet Singh Wadhwa

    2013-01-01

    Full Text Available Aims and Objectives: To determine the time dependent accuracy of casts made from three different irreversible hydrocolloids. Materials and Methods: The effect of delayed pouring on the accuracy of three different irreversible hydrocolloid impression materials - Regular set CA 37(Cavex, The Netherlands, regular set chromatic (Jeltrate, Dentsply, and fast set (Hydrogum soft, Zhermack Clinical was investigated. A brass master die that contained two identical posts simulating two complete crown-tapered abutment preparations with reference grooves served as a standardized master model. A total of 120 impressions were made using specially prepared stock-perforated brass tray with 40 impressions of each material. The impressions were further sub-grouped according to four different storage time intervals: 0 min (immediately, 12 min, 30 min, and 1 h. The impressions were stored at room temperature in a zip-lock plastic bag. Interabutment and intraabutment distances were measured in the recovered stone dies (Type IV, Kalrock using a profile projector with an accuracy of 0.001 mm. The data so obtained was analyzed statistically. Results: Results of this study showed no statistically significant differences in the accuracy of casts obtained at different time intervals. Conclusion: Because it is not always possible to pour the impression immediately in routine clinical practice, all irreversible hydrocolloid materials studied could be stored in a zip-lock plastic bag for upto 1 h without any significant distortion.

  16. Track counting in radon dosimetry

    International Nuclear Information System (INIS)

    Fesenbeck, Ingo; Koehler, Bernd; Reichert, Klaus-Martin

    2013-01-01

    The newly developed, computer-controlled track counting system is capable of imaging and analyzing the entire area of nuclear track detectors. The high optical resolution allows a new analysis approach for the process of automated counting using digital image processing technologies. This way, higher exposed detectors can be evaluated reliably by an automated process as well. (orig.)

  17. CalCOFI Egg Counts Positive Tows

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fish egg counts and standardized counts for eggs captured in CalCOFI icthyoplankton nets (primarily vertical [Calvet or Pairovet], oblique [bongo or ring nets], and...

  18. Time-resolved single-shot terahertz time-domain spectroscopy for ultrafast irreversible processes

    Science.gov (United States)

    Zhai, Zhao-Hui; Zhong, Sen-Cheng; Li, Jun; Zhu, Li-Guo; Meng, Kun; Li, Jiang; Liu, Qiao; Peng, Qi-Xian; Li, Ze-Ren; Zhao, Jian-Heng

    2016-09-01

    Pulsed terahertz spectroscopy is suitable for spectroscopic diagnostics of ultrafast events. However, the study of irreversible or single shot ultrafast events requires ability to record transient properties at multiple time delays, i.e., time resolved at single shot level, which is not available currently. Here by angular multiplexing use of femtosecond laser pulses, we developed and demonstrated a time resolved, transient terahertz time domain spectroscopy technique, where burst mode THz pulses were generated and then detected in a single shot measurement manner. The burst mode THz pulses contain 2 sub-THz pulses, and the time gap between them is adjustable up to 1 ns with picosecond accuracy, thus it can be used to probe the single shot event at two different time delays. The system can detect the sub-THz pulses at 0.1 THz-2.5 THz range with signal to noise ratio (SNR) of ˜400 and spectrum resolution of 0.05 THz. System design was described here, and optimizations of single shot measurement of THz pulses were discussed in detail. Methods to improve SNR were also discussed in detail. A system application was demonstrated where pulsed THz signals at different time delays of the ultrafast process were successfully acquired within single shot measurement. This time resolved transient terahertz time domain spectroscopy technique provides a new diagnostic tool for irreversible or single shot ultrafast events where dynamic information can be extracted at terahertz range within one-shot experiment.

  19. Regression Models For Multivariate Count Data.

    Science.gov (United States)

    Zhang, Yiwen; Zhou, Hua; Zhou, Jin; Sun, Wei

    2017-01-01

    Data with multivariate count responses frequently occur in modern applications. The commonly used multinomial-logit model is limiting due to its restrictive mean-variance structure. For instance, analyzing count data from the recent RNA-seq technology by the multinomial-logit model leads to serious errors in hypothesis testing. The ubiquity of over-dispersion and complicated correlation structures among multivariate counts calls for more flexible regression models. In this article, we study some generalized linear models that incorporate various correlation structures among the counts. Current literature lacks a treatment of these models, partly due to the fact that they do not belong to the natural exponential family. We study the estimation, testing, and variable selection for these models in a unifying framework. The regression models are compared on both synthetic and real RNA-seq data.

  20. Activation of cathepsin L contributes to the irreversible depolarization induced by oxygen and glucose deprivation in rat hippocampal CA1 neurons.

    Science.gov (United States)

    Kikuta, Shogo; Murai, Yoshinaka; Tanaka, Eiichiro

    2017-01-01

    Oxygen and glucose deprivation (OGD) elicits a rapid and irreversible depolarization with a latency of ∼5min in intracellular recordings of hippocampal CA1 neurons in rat slice preparations. In the present study, we examined the role of cathepsin L in the OGD-induced depolarization. OGD-induced depolarizations were irreversible as no recovery of membrane potential was observed. The membrane potential reached 0mV when oxygen and glucose were reintroduced immediately after the onset of the OGD-induced rapid depolarization. The OGD-induced depolarizations became reversible when the slice preparations were pre-incubated with cathepsin L inhibitors (types I and IV at 0.3-2nM and 0.3-30nM, respectively). Moreover, pre-incubation with these cathepsin inhibitors prevented the morphological changes, including swelling of the cell soma and fragmentation of dendrites, observed in control neurons after OGD. These findings suggest that the activation of cathepsin L contributes to the irreversible depolarization produced by OGD. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Validity of total leucocytes count and neutrophil count (differential leucocytes) in diagnosing suspected acute appendicitis

    International Nuclear Information System (INIS)

    Anwar, M.W.; Abid, I.

    2012-01-01

    Objective: To compare the diagnostic accuracy of Total Leucocytes Count (TLC) with Neutrophil count; Differential Leucocytes Count (DLC) in diagnosing cases of suspected acute appendicitis. Study design: Validation study. Place and duration of the study: Department of Surgery, Combined Military Hospital (CMH) Rawalpindi, from April 2008 to October 2008. Method: A total of 100 patients of Pain right iliac fossae who underwent appendicectomy were included. Detailed history of all the patients was taken for pain in right lower abdomen, its severity, its nature, relieving or provoking factors. Clinical examination was done in detail. Total and Differential Leucocytes Count was done. Every patient's appendix was examined grossly after appendicectomy for evidence of appendicitis. Diagnostic measures of TLC and DLC were calculated by standard formulas. Results: Sensitivity and specificity of TLC is 86.9% and 81.25% respectively and that of DLC is 82% and 68.75% respectively. Accuracy was 86% for TLC and 80% for DLC. Conclusion: TLC is more sensitive, specific and accurate test as compared to DLC and it should be used as diagnostic aid for suspected acute appendicitis cases. (author)

  2. Automatic airline baggage counting using 3D image segmentation

    Science.gov (United States)

    Yin, Deyu; Gao, Qingji; Luo, Qijun

    2017-06-01

    The baggage number needs to be checked automatically during baggage self-check-in. A fast airline baggage counting method is proposed in this paper using image segmentation based on height map which is projected by scanned baggage 3D point cloud. There is height drop in actual edge of baggage so that it can be detected by the edge detection operator. And then closed edge chains are formed from edge lines that is linked by morphological processing. Finally, the number of connected regions segmented by closed chains is taken as the baggage number. Multi-bag experiment that is performed on the condition of different placement modes proves the validity of the method.

  3. Enhancing Irreversible Electroporation by Manipulating Cellular Biophysics with a Molecular Adjuvant.

    Science.gov (United States)

    Ivey, Jill W; Latouche, Eduardo L; Richards, Megan L; Lesser, Glenn J; Debinski, Waldemar; Davalos, Rafael V; Verbridge, Scott S

    2017-07-25

    Pulsed electric fields applied to cells have been used as an invaluable research tool to enhance delivery of genes or other intracellular cargo, as well as for tumor treatment via electrochemotherapy or tissue ablation. These processes involve the buildup of charge across the cell membrane, with subsequent alteration of transmembrane potential that is a function of cell biophysics and geometry. For traditional electroporation parameters, larger cells experience a greater degree of membrane potential alteration. However, we have recently demonstrated that the nuclear/cytoplasm ratio (NCR), rather than cell size, is a key predictor of response for cells treated with high-frequency irreversible electroporation (IRE). In this study, we leverage a targeted molecular therapy, ephrinA1, known to markedly collapse the cytoplasm of cells expressing the EphA2 receptor, to investigate how biophysical cellular changes resulting from NCR manipulation affect the response to IRE at varying frequencies. We present evidence that the increase in the NCR mitigates the cell death response to conventional electroporation pulsed-electric fields (∼100 μs), consistent with the previously noted size dependence. However, this same molecular treatment enhanced the cell death response to high-frequency electric fields (∼1 μs). This finding demonstrates the importance of considering cellular biophysics and frequency-dependent effects in developing electroporation protocols, and our approach provides, to our knowledge, a novel and direct experimental methodology to quantify the relationship between cell morphology, pulse frequency, and electroporation response. Finally, this novel, to our knowledge, combinatorial approach may provide a paradigm to enhance in vivo tumor ablation through a molecular manipulation of cellular morphology before IRE application. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  4. Enhanced counting efficiency of Cerenkov radiation from bismuth-210

    International Nuclear Information System (INIS)

    Peck, G.A.; Smith, J.D.

    1998-01-01

    This paper describes the measurement of 210 Bi by Cerenkov counting in a commercial liquid scintillation counter. The counting efficiency in water is 0.17 counts per second per Becquerel (17%). When the enhancers Triton X-100 (15% v/v) and sodium salicylate (1% m/v) are added to the solution the counting efficiency for 210 Bi increases from 17% to 75%. The 210 Po daughter of 210 Bi causes interference of 0.85 counts per second per Becquerel in the presence of the enhancers but not in water. When 210 Bi and 210 Po are present in secular equilibrium the total counting efficiency is 160%. When 210 Bi and 210 Po are not in secular equilibrium the 210 Po can be removed immediately before counting by plating onto silver foil. The use of the enhancers gives a substantial increase in counting efficiency compared to counting in water. Compared with solutions used in liquid scintillation counting the enhancer solution is inexpensive and can be disposed of without environmental hazard. (author)

  5. Clean Hands Count

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    Full Text Available ... why Close Clean Hands Count Centers for Disease Control and Prevention (CDC) Loading... Unsubscribe from Centers for Disease Control and Prevention (CDC)? Cancel Unsubscribe Working... Subscribe Subscribed ...

  6. Blood pressure reduction in patients with irreversible pulpitis teeth treated by non-surgical root canal treatment

    Directory of Open Access Journals (Sweden)

    James I-Sheng Huang

    2017-12-01

    Full Text Available Background/purpose: The hypotension in patients during non-surgical root canal treatment (NSRCT has not yet investigated. This study aimed to assess the mean systolic blood pressure (MSBP, mean diastolic blood pressure (MDBP, and mean arterial blood pressure (MABP reduction percentages in patients with irreversible pulpitis teeth treated by NSRCT. Materials and methods: We prospectively recruited 111 patients with a total of 138 irreversible pulpitis teeth. All patients underwent two NSRCT sessions. The first NSRCT session involved mainly the removal of vital pulp tissue with the direct stimulation of the dental branches of the trigeminal nerve, and the second NSRCT session included the root canal debridement and enlargement with minimal disturbance to the dental nerves. The blood pressure of each patient was recorded before and during both NSRCT sessions. Results: There were significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients (all the P-values < 0.001. If the patients were divided into 2 or more groups according to the clinical variables including the patients' gender, age, tooth type, and anesthesia type, we also found significantly higher reduction percentages of MSBP, MDBP, and MABP in the first NSRCT session than in the second NSRCT session for all treated patients except for patients below 40 years of age and for patients with lower anterior teeth treated (all the P-values < 0.05. Conclusion: The decrease in blood pressure in patients receiving vital pulpal extirpation is a relatively common phenomenon. Keywords: hypotension, irreversible pulpitis teeth, non-surgical root canal treatment, blood pressure, parasympathetic effect, vital pulpal extirpation

  7. Advertising and Irreversible Opinion Spreading in Complex Social Networks

    Science.gov (United States)

    Candia, Julián

    Irreversible opinion spreading phenomena are studied on small-world and scale-free networks by means of the magnetic Eden model, a nonequilibrium kinetic model for the growth of binary mixtures in contact with a thermal bath. In this model, the opinion of an individual is affected by those of their acquaintances, but opinion changes (analogous to spin flips in an Ising-like model) are not allowed. We focus on the influence of advertising, which is represented by external magnetic fields. The interplay and competition between temperature and fields lead to order-disorder transitions, which are found to also depend on the link density and the topology of the complex network substrate. The effects of advertising campaigns with variable duration, as well as the best cost-effective strategies to achieve consensus within different scenarios, are also discussed.

  8. Edge-shape barrier irreversibility and decomposition of vortices in Bi 2Sr 2CaCu 2O 8

    Science.gov (United States)

    Indenbom, M. V.; D'Anna, G.; André, M.-O.; Kabanov, V. V.; Benoit, W.

    1994-12-01

    Magnetic flux dynamics is studied in Bi 2Sr 2CaCu 2O 8 single crystals by means of magneto-optical technique. It is clearly demonstrated that the magnetic irreversibility of these crystals in a magnetic field perpendicular to the basal plane at temperatures higher than approximately 35 K is governed by an edge-shape barrier and its disappearance determines the high temperature part of the magnetic irreversibility line which is commonly associated in the literature with vortex lattice melting. We argue that this barrier exists because of the non ellipsoidal shape of the samples and can disappear only when the flux lines lose their rigidity decomposing into pancakes, which is the only true magnetic phase transition on the B-T diagram for Bi 2Sr 2CaCu 2O 8.

  9. Design and development of multiple sample counting setup

    International Nuclear Information System (INIS)

    Rath, D.P.; Murali, S.; Babu, D.A.R.

    2010-01-01

    Full text: The analysis of active samples on regular basis for ambient air activity and floor contamination from radio chemical lab accounts for major chunk of the operational activity in Health Physicist's responsibility. The requirement for daily air sample analysis on immediate counting and delayed counting from various labs in addition to samples of smear swipe check of lab led to the urge for development of system that could cater multiple sample analysis in a time programmed manner on a single sample loading. A multiple alpha/beta counting system for counting was designed and fabricated. It has arrangements for loading 10 samples in slots in order, get counted in a time programmed manner with results displayed and records maintained in PC. The paper describes the design and development of multiple sample counting setup presently in use at the facility has resulted in reduction of man-hour consumption in counting and recording of the results

  10. Automated vehicle counting using image processing and machine learning

    Science.gov (United States)

    Meany, Sean; Eskew, Edward; Martinez-Castro, Rosana; Jang, Shinae

    2017-04-01

    Vehicle counting is used by the government to improve roadways and the flow of traffic, and by private businesses for purposes such as determining the value of locating a new store in an area. A vehicle count can be performed manually or automatically. Manual counting requires an individual to be on-site and tally the traffic electronically or by hand. However, this can lead to miscounts due to factors such as human error A common form of automatic counting involves pneumatic tubes, but pneumatic tubes disrupt traffic during installation and removal, and can be damaged by passing vehicles. Vehicle counting can also be performed via the use of a camera at the count site recording video of the traffic, with counting being performed manually post-recording or using automatic algorithms. This paper presents a low-cost procedure to perform automatic vehicle counting using remote video cameras with an automatic counting algorithm. The procedure would utilize a Raspberry Pi micro-computer to detect when a car is in a lane, and generate an accurate count of vehicle movements. The method utilized in this paper would use background subtraction to process the images and a machine learning algorithm to provide the count. This method avoids fatigue issues that are encountered in manual video counting and prevents the disruption of roadways that occurs when installing pneumatic tubes

  11. Observer detection of image degradation caused by irreversible data compression processes

    Science.gov (United States)

    Chen, Ji; Flynn, Michael J.; Gross, Barry; Spizarny, David

    1991-05-01

    Irreversible data compression methods have been proposed to reduce the data storage and communication requirements of digital imaging systems. In general, the error produced by compression increases as an algorithm''s compression ratio is increased. We have studied the relationship between compression ratios and the detection of induced error using radiologic observers. The nature of the errors was characterized by calculating the power spectrum of the difference image. In contrast with studies designed to test whether detected errors alter diagnostic decisions, this study was designed to test whether observers could detect the induced error. A paired-film observer study was designed to test whether induced errors were detected. The study was conducted with chest radiographs selected and ranked for subtle evidence of interstitial disease, pulmonary nodules, or pneumothoraces. Images were digitized at 86 microns (4K X 5K) and 2K X 2K regions were extracted. A full-frame discrete cosine transform method was used to compress images at ratios varying between 6:1 and 60:1. The decompressed images were reprinted next to the original images in a randomized order with a laser film printer. The use of a film digitizer and a film printer which can reproduce all of the contrast and detail in the original radiograph makes the results of this study insensitive to instrument performance and primarily dependent on radiographic image quality. The results of this study define conditions for which errors associated with irreversible compression cannot be detected by radiologic observers. The results indicate that an observer can detect the errors introduced by this compression algorithm for compression ratios of 10:1 (1.2 bits/pixel) or higher.

  12. Psychologic adjustment to irreversible vision loss in adults: a systematic review.

    Science.gov (United States)

    Senra, Hugo; Barbosa, Fernando; Ferreira, Patrícia; Vieira, Cristina R; Perrin, Paul B; Rogers, Heather; Rivera, Diego; Leal, Isabel

    2015-04-01

    To summarize relevant evidence investigating the psychologic adjustment to irreversible vision loss (IVL) in adults. Irreversible vision loss entails a challenging medical condition in which rehabilitation outcomes are strongly dependent on the patient's psychologic adjustment to illness and impairment. So far, no study has systematically reviewed the psychologic adjustment to IVL in adults. We reviewed all articles examining the psychologic adjustment to IVL in adults. We included articles published in English in peer-reviewed journals. We performed a keyword literature search using 4 databases (PubMed, EBSCO, Cochrane Library, and Science Direct) for all years through July 2014. We assessed risk of bias of selected studies using the RTI Item Bank for Assessing Risk of Bias and Confounding for Observational Studies of Interventions or Exposures and the Cochrane risk of bias tool for randomized controlled trials. Of a total of 3948 citations retrieved, we selected 52 eligible studies published between 1946 and 2014. The majority of studies were observational and cross-sectional in nature. Our review suggests that high levels of depression occur during the adjustment to IVL. Better adjustment to IVL was associated with greater acceptance of vision loss and use of instrumental coping, good social support, positivity, and use of assistive aids. The overall findings indicate that IVL often has negative effects on patients' quality of life and mental health and that such effects tend to remain over time. Specific factors and variables associated with the adjustment to IVL need to be clarified through further in-depth and longitudinal research. Copyright © 2015 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  13. Calculating concentration of inhaled radiolabeled particles from external gamma counting: External counting efficiency and attenuation coefficient of thorax

    International Nuclear Information System (INIS)

    Langenback, E.G.; Foster, W.M.; Bergofsky, E.H.

    1989-01-01

    We determined the overall external counting efficiency of radiolabeled particles deposited in the sheep lung. This efficiency permits the noninvasive calculation of the number of particles and microcuries from gamma-scintillation lung images of the live sheep. Additionally, we have calculated the attenuation of gamma radiation (120 keV) by the posterior chest wall and the gamma-scintillation camera collection efficiency of radiation emitted from the lung. Four methods were employed in our experiments: (1) by light microscopic counting of discrete carbonized polystyrene particles with a count median diameter (CMD) of 2.85 microns and tagged with cobalt-57, we delineated a linear relationship between the number of particles and the emitted counts per minute (cpm) detected by well scintillation counting; (2) from this conversion relationship we determined the number of particles inhaled and deposited in the lungs by scintillation counting fragments of dissected lung at autopsy; (3) we defined a linear association between the number of particles or microcuries contained in the lung and the emitted radiation as cpm detected by a gamma scintillation camera in the live sheep prior to autopsy; and (4) we compared the emitted radiation from the lungs of the live sheep to that of whole excised lungs in order to calculate the attenuation coefficient (ac) of the chest wall. The mean external counting efficiency was 4.00 X 10(4) particles/cpm (5.1 X 10(-3) microCi/cpm), the camera collection efficiency was 1 cpm/10(4) disintegrations per minute (dpm), and the ac had a mean of 0.178/cm. The external counting efficiency remained relatively constant over a range of particles and microcuries, permitting a more general use of this ratio to estimate number of particles or microcuries depositing after inhalation in a large mammalian lung if a similarly collimated gamma camera system is used

  14. Clean Hands Count

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    Full Text Available ... Clean Hands Count Centers for Disease Control and Prevention (CDC) Loading... Unsubscribe from Centers for Disease Control and Prevention (CDC)? Cancel Unsubscribe Working... Subscribe Subscribed Unsubscribe 65K ...

  15. Clean Hands Count

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    Full Text Available ... Clean Hands Count Centers for Disease Control and Prevention (CDC) Loading... Unsubscribe from Centers for Disease Control and Prevention (CDC)? Cancel Unsubscribe Working... Subscribe Subscribed Unsubscribe 66K ...

  16. Algorithm for counting large directed loops

    Energy Technology Data Exchange (ETDEWEB)

    Bianconi, Ginestra [Abdus Salam International Center for Theoretical Physics, Strada Costiera 11, 34014 Trieste (Italy); Gulbahce, Natali [Theoretical Division and Center for Nonlinear Studies, Los Alamos National Laboratory, NM 87545 (United States)

    2008-06-06

    We derive a Belief-Propagation algorithm for counting large loops in a directed network. We evaluate the distribution of the number of small loops in a directed random network with given degree sequence. We apply the algorithm to a few characteristic directed networks of various network sizes and loop structures and compare the algorithm with exhaustive counting results when possible. The algorithm is adequate in estimating loop counts for large directed networks and can be used to compare the loop structure of directed networks and their randomized counterparts.

  17. Logistic regression for dichotomized counts.

    Science.gov (United States)

    Preisser, John S; Das, Kalyan; Benecha, Habtamu; Stamm, John W

    2016-12-01

    Sometimes there is interest in a dichotomized outcome indicating whether a count variable is positive or zero. Under this scenario, the application of ordinary logistic regression may result in efficiency loss, which is quantifiable under an assumed model for the counts. In such situations, a shared-parameter hurdle model is investigated for more efficient estimation of regression parameters relating to overall effects of covariates on the dichotomous outcome, while handling count data with many zeroes. One model part provides a logistic regression containing marginal log odds ratio effects of primary interest, while an ancillary model part describes the mean count of a Poisson or negative binomial process in terms of nuisance regression parameters. Asymptotic efficiency of the logistic model parameter estimators of the two-part models is evaluated with respect to ordinary logistic regression. Simulations are used to assess the properties of the models with respect to power and Type I error, the latter investigated under both misspecified and correctly specified models. The methods are applied to data from a randomized clinical trial of three toothpaste formulations to prevent incident dental caries in a large population of Scottish schoolchildren. © The Author(s) 2014.

  18. A Review of Multivariate Distributions for Count Data Derived from the Poisson Distribution.

    Science.gov (United States)

    Inouye, David; Yang, Eunho; Allen, Genevera; Ravikumar, Pradeep

    2017-01-01

    The Poisson distribution has been widely studied and used for modeling univariate count-valued data. Multivariate generalizations of the Poisson distribution that permit dependencies, however, have been far less popular. Yet, real-world high-dimensional count-valued data found in word counts, genomics, and crime statistics, for example, exhibit rich dependencies, and motivate the need for multivariate distributions that can appropriately model this data. We review multivariate distributions derived from the univariate Poisson, categorizing these models into three main classes: 1) where the marginal distributions are Poisson, 2) where the joint distribution is a mixture of independent multivariate Poisson distributions, and 3) where the node-conditional distributions are derived from the Poisson. We discuss the development of multiple instances of these classes and compare the models in terms of interpretability and theory. Then, we empirically compare multiple models from each class on three real-world datasets that have varying data characteristics from different domains, namely traffic accident data, biological next generation sequencing data, and text data. These empirical experiments develop intuition about the comparative advantages and disadvantages of each class of multivariate distribution that was derived from the Poisson. Finally, we suggest new research directions as explored in the subsequent discussion section.

  19. Irreversibility of entanglement distillation for a class of symmetric states

    International Nuclear Information System (INIS)

    Vollbrecht, Karl Gerd H.; Wolf, Michael M.; Werner, Reinhard F.

    2004-01-01

    We investigate the irreversibility of entanglement distillation for a symmetric (d+1)-parameter family of mixed bipartite quantum states acting on Hilbert spaces of arbitrary dimension dxd. We prove that in this family the entanglement cost is generically strictly larger than the distillable entanglement, so that the set of states for which the distillation process is asymptotically reversible is of measure zero. This remains true even if the distillation process is catalytically assisted by pure-state entanglement and every operation is allowed, which preserves the positivity of the partial transpose. It is shown that reversibility occurs only in cases where the state is a tagged mixture. The reversible cases are shown to be completely characterized by minimal uncertainty vectors for entropic uncertainty relations

  20. Housing Inventory Count

    Data.gov (United States)

    Department of Housing and Urban Development — This report displays the data communities reported to HUD about the nature of their dedicated homeless inventory, referred to as their Housing Inventory Count (HIC)....

  1. Multiple-Event, Single-Photon Counting Imaging Sensor

    Science.gov (United States)

    Zheng, Xinyu; Cunningham, Thomas J.; Sun, Chao; Wang, Kang L.

    2011-01-01

    The single-photon counting imaging sensor is typically an array of silicon Geiger-mode avalanche photodiodes that are monolithically integrated with CMOS (complementary metal oxide semiconductor) readout, signal processing, and addressing circuits located in each pixel and the peripheral area of the chip. The major problem is its single-event method for photon count number registration. A single-event single-photon counting imaging array only allows registration of up to one photon count in each of its pixels during a frame time, i.e., the interval between two successive pixel reset operations. Since the frame time can t be too short, this will lead to very low dynamic range and make the sensor merely useful for very low flux environments. The second problem of the prior technique is a limited fill factor resulting from consumption of chip area by the monolithically integrated CMOS readout in pixels. The resulting low photon collection efficiency will substantially ruin any benefit gained from the very sensitive single-photon counting detection. The single-photon counting imaging sensor developed in this work has a novel multiple-event architecture, which allows each of its pixels to register as more than one million (or more) photon-counting events during a frame time. Because of a consequently boosted dynamic range, the imaging array of the invention is capable of performing single-photon counting under ultra-low light through high-flux environments. On the other hand, since the multiple-event architecture is implemented in a hybrid structure, back-illumination and close-to-unity fill factor can be realized, and maximized quantum efficiency can also be achieved in the detector array.

  2. Lazy reference counting for the Microgrid

    NARCIS (Netherlands)

    Poss, R.; Grelck, C.; Herhut, S.; Scholz, S.-B.

    2012-01-01

    This papers revisits non-deferred reference counting, a common technique to ensure that potentially shared large heap objects can be reused safely when they are both input and output to computations. Traditionally, thread-safe reference counting exploit implicit memory-based communication of counter

  3. Did Illegally Counted Overseas Absentee Ballots Decide the 2000 U.S. Presidential Election?

    OpenAIRE

    Imai, Kosuke; King, Gary

    2004-01-01

    Although not widely known until much later, Al Gore received 202 more votes than George W. Bush on election day in Florida. George W. Bush is president because he overcame his election day deficit with overseas absentee ballots that arrived and were counted after election day. In the final official tally, Bush received 537 more votes than Gore. These numbers are taken from the official results released by the Florida Secretary of State’s office and so do not reflect overvotes, undervotes, uns...

  4. Clean Hands Count

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    Full Text Available ... stop Loading... Watch Queue Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with zero ads? Get YouTube Red. Working... Not now Try it free Find ...

  5. Global analysis of myocardial peptides containing cysteines with irreversible sulfinic and sulfonic Acid post-translational modifications

    DEFF Research Database (Denmark)

    Paulech, Jana; Liddy, Kiersten A; Engholm-Keller, Kasper

    2015-01-01

    ) and others (Cys sulfinic [Cys-SO2H] and sulfonic [Cys-SO3H] acids) that are considered "irreversible." We developed an enrichment method to isolate Cys-SO2H/SO3H-containing peptides from complex tissue lysates that is compatible with tandem mass spectrometry (MS/MS). The acidity of these post...

  6. Preverbal and verbal counting and computation.

    Science.gov (United States)

    Gallistel, C R; Gelman, R

    1992-08-01

    We describe the preverbal system of counting and arithmetic reasoning revealed by experiments on numerical representations in animals. In this system, numerosities are represented by magnitudes, which are rapidly but inaccurately generated by the Meck and Church (1983) preverbal counting mechanism. We suggest the following. (1) The preverbal counting mechanism is the source of the implicit principles that guide the acquisition of verbal counting. (2) The preverbal system of arithmetic computation provides the framework for the assimilation of the verbal system. (3) Learning to count involves, in part, learning a mapping from the preverbal numerical magnitudes to the verbal and written number symbols and the inverse mappings from these symbols to the preverbal magnitudes. (4) Subitizing is the use of the preverbal counting process and the mapping from the resulting magnitudes to number words in order to generate rapidly the number words for small numerosities. (5) The retrieval of the number facts, which plays a central role in verbal computation, is mediated via the inverse mappings from verbal and written numbers to the preverbal magnitudes and the use of these magnitudes to find the appropriate cells in tabular arrangements of the answers. (6) This model of the fact retrieval process accounts for the salient features of the reaction time differences and error patterns revealed by experiments on mental arithmetic. (7) The application of verbal and written computational algorithms goes on in parallel with, and is to some extent guided by, preverbal computations, both in the child and in the adult.

  7. Determining Gate Count Reliability in a Library Setting

    OpenAIRE

    Jeffrey Phillips

    2016-01-01

    Objective – Patron counts are a common form of measurement for library assessment. To develop accurate library statistics, it is necessary to determine any differences between various counting devices. A yearlong comparison between card reader turnstiles and laser gate counters in a university library sought to offer a standard percentage of variance and provide suggestions to increase the precision of counts. Methods – The collection of library exit counts identified the differences be...

  8. Anesthetic efficacy of X-tip intraosseous injection using 2% lidocaine with 1:80,000 epinephrine in patients with irreversible pulpitis after inferior alveolar nerve block: A clinical study.

    Science.gov (United States)

    Verma, Pushpendra Kumar; Srivastava, Ruchi; Ramesh, Kumar M

    2013-03-01

    The inferior alveolar nerve block (IAN) is the most frequently used mandibular injection technique for achieving local anesthesia in endodontics. Supplemental injections are essential to overcome failure of IAN block in patients with irreversible pulpitis. To evaluate the anesthetic efficacy of X-tip intraosseous injection (2% lidocaine with 1:80,000 epinephrine) in patients with irreversible pulpitis in mandibular posterior teeth when conventional IAN block failed. Thirty emergency patients diagnosed with irreversible pulpitis in a mandibular posterior tooth received an IAN block and experienced moderate to severe pain on endodontic access or initial instrumentation. The X-tip system was used to administer 1.8 ml of 2% lidocaine with 1:80,000 epinephrine. The success of X-tip intraosseous injection was defined as none or mild pain (Heft-Parker visual analogue scale ratings intraosseous injection using 2% lignocaine with 1:80,000 epinephrine has a statistically significant influence in achieving pulpal anesthesia in patients with irreversible pulpitis.

  9. Anesthetic efficacy of X-tip intraosseous injection using 2% lidocaine with 1:80,000 epinephrine in patients with irreversible pulpitis after inferior alveolar nerve block: A clinical study

    Science.gov (United States)

    Verma, Pushpendra Kumar; Srivastava, Ruchi; Ramesh, Kumar M

    2013-01-01

    Introduction: The inferior alveolar nerve block (IAN) is the most frequently used mandibular injection technique for achieving local anesthesia in endodontics. Supplemental injections are essential to overcome failure of IAN block in patients with irreversible pulpitis. Aim: To evaluate the anesthetic efficacy of X-tip intraosseous injection (2% lidocaine with 1:80,000 epinephrine) in patients with irreversible pulpitis in mandibular posterior teeth when conventional IAN block failed. Materials and Methods: Thirty emergency patients diagnosed with irreversible pulpitis in a mandibular posterior tooth received an IAN block and experienced moderate to severe pain on endodontic access or initial instrumentation. The X-tip system was used to administer 1.8 ml of 2% lidocaine with 1:80,000 epinephrine. The success of X-tip intraosseous injection was defined as none or mild pain (Heft-Parker visual analogue scale ratings intraosseous injection using 2% lignocaine with 1:80,000 epinephrine has a statistically significant influence in achieving pulpal anesthesia in patients with irreversible pulpitis. PMID:23716971

  10. Counting Word Frequencies with Python

    Directory of Open Access Journals (Sweden)

    William J. Turkel

    2012-07-01

    Full Text Available Your list is now clean enough that you can begin analyzing its contents in meaningful ways. Counting the frequency of specific words in the list can provide illustrative data. Python has an easy way to count frequencies, but it requires the use of a new type of variable: the dictionary. Before you begin working with a dictionary, consider the processes used to calculate frequencies in a list.

  11. Computerized radioautographic grain counting

    International Nuclear Information System (INIS)

    McKanna, J.A.; Casagrande, V.A.

    1985-01-01

    In recent years, radiolabeling techniques have become fundamental assays in physiology and biochemistry experiments. They also have assumed increasingly important roles in morphologic studies. Characteristically, radioautographic analysis of structure has been qualitative rather than quantitative, however, microcomputers have opened the door to several methods for quantifying grain counts and density. The overall goal of this chapter is to describe grain counting using the Bioquant, an image analysis package based originally on the Apple II+, and now available for several popular microcomputers. The authors discuss their image analysis procedures by applying them to a study of development in the central nervous system

  12. Preliminary study of steep pulse irreversible electroporation technology in human large cell lung cancer cell lines L9981

    Directory of Open Access Journals (Sweden)

    Song Zuoqing

    2013-01-01

    Full Text Available Our aim was to validate the effectiveness of steep pulse irreversible electroporation technology in human large cell lung cancer cells and to screen the optimal treatment of parameters for human large cell lung cancer cells. Three different sets of steep pulse therapy parameters were applied on the lung cancer cell line L9981. The cell line L9981 inhibition rate and proliferation capacity were detected by Vi-Cell vitality analysis and MTT. Steep pulsed irreversible electroporation technology for large cell lung cancer L9981 presents killing effects with various therapy parameters. The optimal treatment parameters are at a voltage amplitude of 2000V/cm, pulse width of 100μs, pulse frequency of 1 Hz, pulse number 10. With this group of parameters, steep pulse could have the best tumor cell-killing effects.

  13. Ac irreversibility line of bismuth-based high temperature superconductors

    International Nuclear Information System (INIS)

    Mehdaoui, A.; Beille, J.; Berling, D.; Loegel, B.; Noudem, J.G.; Tournier, R.

    1997-01-01

    We discuss the magnetic properties of lead doped Bi-2223 bulk samples obtained through combined magnetic melt texturing and hot pressing (MMTHP). The ac complex susceptibility measurements are achieved over a broad ac field range (1 Oe ac <100 Oe) and show highly anisotropic properties. The intergranular coupling is improved in the direction perpendicular to the applied stress and magnetic field direction, and an intragranular loss peak is observed for the first time. A comparison is made with other bismuth-based compounds and it is shown that the MMTHP process shifts the ac irreversibility line (ac IL) toward higher fields. It is also shown that all the ac IL close-quote s for quasi 2D bismuth-based compounds show a nearly quadratic temperature dependence and deviate therefore strongly from the linear behavior observed in quasi 3D compounds and expected from a critical state model.copyright 1997 Materials Research Society

  14. The use of plant models in deep learning: an application to leaf counting in rosette plants.

    Science.gov (United States)

    Ubbens, Jordan; Cieslak, Mikolaj; Prusinkiewicz, Przemyslaw; Stavness, Ian

    2018-01-01

    Deep learning presents many opportunities for image-based plant phenotyping. Here we consider the capability of deep convolutional neural networks to perform the leaf counting task. Deep learning techniques typically require large and diverse datasets to learn generalizable models without providing a priori an engineered algorithm for performing the task. This requirement is challenging, however, for applications in the plant phenotyping field, where available datasets are often small and the costs associated with generating new data are high. In this work we propose a new method for augmenting plant phenotyping datasets using rendered images of synthetic plants. We demonstrate that the use of high-quality 3D synthetic plants to augment a dataset can improve performance on the leaf counting task. We also show that the ability of the model to generate an arbitrary distribution of phenotypes mitigates the problem of dataset shift when training and testing on different datasets. Finally, we show that real and synthetic plants are significantly interchangeable when training a neural network on the leaf counting task.

  15. Effect of nitrous oxide on the efficacy of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.

    Science.gov (United States)

    Stanley, William; Drum, Melissa; Nusstein, John; Reader, Al; Beck, Mike

    2012-05-01

    The inferior alveolar nerve (IAN) block does not always result in successful pulpal anesthesia. Anesthetic success rates might be affected by increased anxiety. Nitrous oxide has been shown to have both anxiolytic and analgesic properties. Therefore, the purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of nitrous oxide on the anesthetic success of the IAN block in patients experiencing symptomatic irreversible pulpitis. One hundred emergency patients diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth were enrolled in this study. Each patient was randomly assigned to receive an inhalation regimen of nitrous oxide/oxygen mix or room air/oxygen mix (placebo) 5 minutes before the administration of the IAN block. Endodontic access was begun 15 minutes after completion of the IAN block, and all patients had profound lip numbness. Success was defined as no or mild pain (visual analog scale recordings) on access or instrumentation. The success rate for the IAN block was 50% for the nitrous oxide group and 28% for the placebo group. There was a statistically significant difference between the 2 groups (P = .024). For mandibular teeth diagnosed with symptomatic irreversible pulpitis, administration of 30%-50% nitrous oxide resulted in a statistically significant increase in the success of the IAN block compared with room air/oxygen. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  16. A master equation for force distributions in soft particle packings - Irreversible mechanical responses to isotropic compression and decompression

    NARCIS (Netherlands)

    Saitoh, K.; Magnanimo, Vanessa; Luding, Stefan

    2016-01-01

    Mechanical responses of soft particle packings to quasi-static deformations are determined by the microscopic restructuring of force-chain networks, where complex non-affine displacements of constituent particles cause the irreversible macroscopic behavior. Recently, we have proposed a master

  17. Cerenkov counting and Cerenkov-scintillation counting with high refractive index organic liquids using a liquid scintillation counter

    International Nuclear Information System (INIS)

    Wiebe, L.I.; Helus, F.; Maier-Borst, W.

    1978-01-01

    18 F and 14 C radioactivity was measured in methyl salicylate (MS), a high refractive index hybrid Cherenkov-scintillation generating medium, using a liquid scintillation counter. At concentrations of up to 21.4%, in MS, dimethyl sulfoxide (DMSO) quenched 14 C fluorescence, and with a 10-fold excess of DMSO over MS, 18 F count rates were reduced below that for DMSO alone, probably as a result of concentration-independent self-quenching due to 'dark-complex' formation. DMSO in lower concentrations did not reduce the counting efficiency of 18 F in MS. Nitrobenzene was a concentration-dependent quencher for both 14 C and 18 F in MS. Chlorobenzene (CB) and DMSO were both found to be weak Cherenkov generators with 18 F. Counting efficiencies for 18 F in MS, CB, and DMSO were 50.3, 7.8 and 4.3% respectively in the coincidence counting mode, and 58.1, 13.0 and 6.8% in the singles mode. 14 C efficiencies were 14.4 and 22.3% for coincidence and singles respectively, and 15.3 and 42.0% using a modern counter designed for coincidence and single photon counting. The high 14 C and 18 F counting efficiency in MS are discussed with respect to excitation mechanism, on the basis of quench and channels ratios changes observed. It is proposed that MS functions as an efficient Cherenkov-scintillation generator for high-energy beta emitters such as 18 F, and as a low-efficiency scintillator for weak beta emitting radionuclides such as 14 C. (author)

  18. Relationship between salivary flow rates and Candida albicans counts.

    Science.gov (United States)

    Navazesh, M; Wood, G J; Brightman, V J

    1995-09-01

    Seventy-one persons (48 women, 23 men; mean age, 51.76 years) were evaluated for salivary flow rates and Candida albicans counts. Each person was seen on three different occasions. Samples of unstimulated whole, chewing-stimulated whole, acid-stimulated parotid, and candy-stimulated parotid saliva were collected under standardized conditions. An oral rinse was also obtained and evaluated for Candida albicans counts. Unstimulated and chewing-stimulated whole flow rates were negatively and significantly (p Candida counts. Unstimulated whole saliva significantly (p Candida counts of 0 versus or = 500 count. Differences in stimulated parotid flow rates were not significant among different levels of Candida counts. The results of this study reveal that whole saliva is a better predictor than parotid saliva in identification of persons with high Candida albicans counts.

  19. Irreversible Markov chains in spin models: Topological excitations

    Science.gov (United States)

    Lei, Ze; Krauth, Werner

    2018-01-01

    We analyze the convergence of the irreversible event-chain Monte Carlo algorithm for continuous spin models in the presence of topological excitations. In the two-dimensional XY model, we show that the local nature of the Markov-chain dynamics leads to slow decay of vortex-antivortex correlations while spin waves decorrelate very quickly. Using a Fréchet description of the maximum vortex-antivortex distance, we quantify the contributions of topological excitations to the equilibrium correlations, and show that they vary from a dynamical critical exponent z∼ 2 at the critical temperature to z∼ 0 in the limit of zero temperature. We confirm the event-chain algorithm's fast relaxation (corresponding to z = 0) of spin waves in the harmonic approximation to the XY model. Mixing times (describing the approach towards equilibrium from the least favorable initial state) however remain much larger than equilibrium correlation times at low temperatures. We also describe the respective influence of topological monopole-antimonopole excitations and of spin waves on the event-chain dynamics in the three-dimensional Heisenberg model.

  20. Reversibility and irreversibility from an initial value formulation

    International Nuclear Information System (INIS)

    Muriel, A.

    2013-01-01

    From a time evolution equation for the single particle distribution function derived from the N-particle distribution function (A. Muriel, M. Dresden, Physica D 101 (1997) 297), an exact solution for the 3D Navier–Stokes equation – an old problem – has been found (A. Muriel, Results Phys. 1 (2011) 2). In this Letter, a second exact conclusion from the above-mentioned work is presented. We analyze the time symmetry properties of a formal, exact solution for the single-particle distribution function contracted from the many-body Liouville equation. This analysis must be done because group theoretic results on time reversal symmetry of the full Liouville equation (E.C.G. Sudarshan, N. Mukunda, Classical Mechanics: A Modern Perspective, Wiley, 1974). no longer applies automatically to the single particle distribution function contracted from the formal solution of the N-body Liouville equation. We find the following result: if the initial momentum distribution is even in the momentum, the single particle distribution is reversible. If there is any asymmetry in the initial momentum distribution, no matter how small, the system is irreversible.

  1. Reticulocyte Count Test

    Science.gov (United States)

    ... htm. (2004 Summer). Immature Reticulocyte Fraction(IRF). The Pathology Center Newsletter v9(1). [On-line information]. Available ... Company, Philadelphia, PA [18th Edition]. Levin, M. (2007 March 8, Updated). Reticulocyte Count. MedlinePlus Medical Encyclopedia [On- ...

  2. Temporal trends in sperm count

    DEFF Research Database (Denmark)

    Levine, Hagai; Jørgensen, Niels; Martino-Andrade, Anderson

    2017-01-01

    a predefined protocol 7518 abstracts were screened and 2510 full articles reporting primary data on SC were reviewed. A total of 244 estimates of SC and TSC from 185 studies of 42 935 men who provided semen samples in 1973-2011 were extracted for meta-regression analysis, as well as information on years.......006, respectively). WIDER IMPLICATIONS: This comprehensive meta-regression analysis reports a significant decline in sperm counts (as measured by SC and TSC) between 1973 and 2011, driven by a 50-60% decline among men unselected by fertility from North America, Europe, Australia and New Zealand. Because......BACKGROUND: Reported declines in sperm counts remain controversial today and recent trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm count for fertility, morbidity and mortality. OBJECTIVE AND RATIONALE: To provide a systematic review and meta-regression...

  3. CERNDxCTA counting mode chip

    International Nuclear Information System (INIS)

    Moraes, D.; Kaplon, J.; Nygard, E.

    2008-01-01

    This ASIC is a counting mode front-end electronic optimized for the readout of CdZnTe/CdTe and silicon sensors, for possible use in applications where the flux of ionizing radiation is high. The chip is implemented in 0.25 μm CMOS technology. The circuit comprises 128 channels equipped with a transimpedance amplifier followed by a gain shaper stage with 21 ns peaking time, two discriminators and two 18-bit counters. The channel architecture is optimized for the detector characteristics in order to achieve the best energy resolution at counting rates of up to 5 M counts/second. The amplifier shows a linear sensitivity of 118 mV/fC and an equivalent noise charge of about 711 e - , for a detector capacitance of 5 pF. Complete evaluation of the circuit is presented using electronic pulses and pixel detectors

  4. Seed counting system evaluation using arduino microcontroller

    Directory of Open Access Journals (Sweden)

    Paulo Fernando Escobar Paim

    2018-01-01

    Full Text Available The development of automated systems has been highlighted in the most diverse productive sectors, among them, the agricultural sector. These systems aim to optimize activities by increasing operational efficiency and quality of work. In this sense, the present work has the objective of evaluating a prototype developed for seed count in laboratory, using Arduino microcontroller. The prototype of the system for seed counting was built using a dosing mechanism commonly used in seeders, electric motor, Arduino Uno, light dependent resistor and light emitting diode. To test the prototype, a completely randomized design (CRD was used in a two-factorial scheme composed of three groups defined according to the number of seeds (500, 1000 and 1500 seeds tested, three speeds of the dosing disc that allowed the distribution in 17, 21 and 32 seeds per second, with 40 repetitions evaluating the seed counting prototype performance in different speeds. The prototype of the bench counter showed a moderate variability of seed number of counted within the nine tests and a high precision in the seed count on the distribution speeds of 17 and 21 seeds per second (s-1 up to 1500 seeds tested. Therefore, based on the observed results, the developed prototype presents itself as an excellent tool for counting seeds in laboratory.

  5. Percutaneous Irreversible Electroporation of Unresectable Hilar Cholangiocarcinoma (Klatskin Tumor): A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Melenhorst, Marleen C. A. M., E-mail: m.melenhorst@vumc.nl; Scheffer, Hester J., E-mail: hj.scheffer@vumc.nl; Vroomen, Laurien G. P. H., E-mail: la.vroomen@vumc.nl [VU University Medical Center, Department of Radiology and Nuclear Medicine (Netherlands); Kazemier, Geert, E-mail: g.kazemier@vumc.nl; Tol, M. Petrousjka van den, E-mail: mp.vandentol@vumc.nl [VU University Medical Center, Department of Surgery (Netherlands); Meijerink, Martijn R., E-mail: mr.meijerink@vumc.nl [VU University Medical Center, Department of Radiology and Nuclear Medicine (Netherlands)

    2016-01-15

    Irreversible electroporation (IRE) is a novel image-guided ablation technique that is rapidly gaining popularity in the treatment of malignant tumors located near large vessels or bile ducts. The presence of metal objects in the ablation zone, such as Wallstents, is generally considered a contraindication for IRE, because tissue heating due to power conduction may lead to thermal complications. This report describes a 66-year-old female with a Bismuth–Corlette stage IV unresectable cholangiocarcinoma with a metallic Wallstent in the common bile duct, who was safely treated with percutaneous IRE with no signs for relapse 1 year after the procedure.

  6. Using DNA to test the utility of pellet-group counts as an index of deer counts

    Science.gov (United States)

    T. J. Brinkman; D. K. Person; W. Smith; F. Stuart Chapin; K. McCoy; M. Leonawicz; K. Hundertmark

    2013-01-01

    Despite widespread use of fecal pellet-group counts as an index of ungulate density, techniques used to convert pellet-group numbers to ungulate numbers rarely are based on counts of known individuals, seldom evaluated across spatial and temporal scales, and precision is infrequently quantified. Using DNA from fecal pellets to identify individual deer, we evaluated the...

  7. Tutorial on X-ray photon counting detector characterization.

    Science.gov (United States)

    Ren, Liqiang; Zheng, Bin; Liu, Hong

    2018-01-01

    Recent advances in photon counting detection technology have led to significant research interest in X-ray imaging. As a tutorial level review, this paper covers a wide range of aspects related to X-ray photon counting detector characterization. The tutorial begins with a detailed description of the working principle and operating modes of a pixelated X-ray photon counting detector with basic architecture and detection mechanism. Currently available methods and techniques for charactering major aspects including energy response, noise floor, energy resolution, count rate performance (detector efficiency), and charge sharing effect of photon counting detectors are comprehensively reviewed. Other characterization aspects such as point spread function (PSF), line spread function (LSF), contrast transfer function (CTF), modulation transfer function (MTF), noise power spectrum (NPS), detective quantum efficiency (DQE), bias voltage, radiation damage, and polarization effect are also remarked. A cadmium telluride (CdTe) pixelated photon counting detector is employed for part of the characterization demonstration and the results are presented. This review can serve as a tutorial for X-ray imaging researchers and investigators to understand, operate, characterize, and optimize photon counting detectors for a variety of applications.

  8. Disinfection procedures: their efficacy and effect on dimensional accuracy and surface quality of an irreversible hydrocolloid impression material.

    LENUS (Irish Health Repository)

    Rentzia, A

    2011-02-01

    This study investigated the antibacterial efficacy and effect of 0.55% ortho-phthalaldehyde (Cidex OPA(®)) and 0.5% sodium hypochlorite (NaOCl) on the dimensional accuracy and surface quality of gypsum casts retrieved from an irreversible hydrocolloid impression material.

  9. Anesthetic efficacy of the supplemental X-tip intraosseous injection using 4% articaine with 1:100,000 adrenaline in patients with irreversible pulpitis: An in vivo study.

    Science.gov (United States)

    Bhuyan, Atool Chandra; Latha, Satheesh Sasidharan; Jain, Shefali; Kataki, Rubi

    2014-11-01

    Pain management remains the utmost important qualifying criteria in minimizing patient agony and establishing a strong dentist-patient rapport. Symptomatic irreversible pulpitis is a painful condition necessitating immediate attention and supplemental anesthetic techniques are often resorted to in addition to conventional inferior alveolar nerve block. The purpose of the study was to evaluate the anesthetic efficacy of X-tip intraosseous injection in patients with symptomatic irreversible pulpitis, in mandibular posterior teeth, using 4% Articaine with 1:100,000 adrenaline as local anesthetic, when the conventional inferior alveolar nerve block proved ineffective. X-tip system was used to administer 1.7 ml of 4% articaine with 1:100,000 adrenaline in 30 patients diagnosed with irreversible pulpitis of mandibular posterior teeth with moderate to severe pain on endodontic access after administration of an inferior alveolar nerve block. The results of the study showed that 25 X-tip injections (83.33%) were successful and 5 X-tip injections (16.66%) were unsuccessful. When the inferior alveolar nerve block fails to provide adequate pulpal anesthesia, X-tip system using 4% articaine with 1:100,000 adrenaline was successful in achieving pulpal anesthesia in patients with irreversible pulpitis.

  10. Scintillation counting apparatus

    International Nuclear Information System (INIS)

    Noakes, J.E.

    1978-01-01

    Apparatus is described for the accurate measurement of radiation by means of scintillation counters and in particular for the liquid scintillation counting of both soft beta radiation and gamma radiation. Full constructional and operating details are given. (UK)

  11. Project and construction of counting system for neutron probe

    International Nuclear Information System (INIS)

    Monteiro, W.P.

    1985-01-01

    A counting system was developed for coupling neutron probe aiming to register pulses produced by slow neutron interaction in the detector. The neutron probe consists of fast neutron source, thermal neutron detector, amplifier circuit and pulse counting circuit. The counting system is composed by counting circuit, timer and signal circuit. (M.C.K.)

  12. White blood cell and platelet count as adjuncts to standard clinical evaluation for risk assessment in patients at low probability of acute aortic syndrome.

    Science.gov (United States)

    Morello, Fulvio; Cavalot, Giulia; Giachino, Francesca; Tizzani, Maria; Nazerian, Peiman; Carbone, Federica; Pivetta, Emanuele; Mengozzi, Giulio; Moiraghi, Corrado; Lupia, Enrico

    2017-08-01

    Pre-test probability assessment is key in the approach to suspected acute aortic syndromes (AASs). However, most patients with AAS-compatible symptoms are classified at low probability, warranting further evaluation for decision on aortic imaging. White blood cell count, platelet count and fibrinogen explore pathophysiological pathways mobilized in AASs and are routinely assayed in the workup of AASs. However, the diagnostic performance of these variables for AASs, alone and as a bundle, is unknown. We tested the hypothesis that white blood cell count, platelet count and/or fibrinogen at presentation may be applied as additional tools to standard clinical evaluation for pre-test risk assessment in patients at low probability of AAS. This was a retrospective observational study conducted on consecutive patients managed in our Emergency Department from 2009 to 2014 for suspected AAS. White blood cell count, platelet count and fibrinogen were assayed during evaluation in the Emergency Department. The final diagnosis was obtained by computed tomography angiography. The pre-test probability of AAS was defined according to guidelines. Of 1210 patients with suspected AAS, 1006 (83.1%) were classified at low probability, and 271 (22.4%) were diagnosed with AAS. Within patients at low probability, presence of at least one alteration among white blood cell count >9*10 3 /µl, platelet count probability, white blood cell count >9*10 3 /µl and platelet count probability, the estimated risk of AAS based on the number of alterations amongst white blood cell count >9*10 3 /µl and platelet count probability to fine-tune risk assessment of AAS.

  13. Measurement of local blood flow and oxygen consumption in evolving irreversible cerebral infarction: an in vivo study in man

    International Nuclear Information System (INIS)

    Baron, J.C.; Rougemont, D.; Lebrun-Grandie, P.; Bousser, M.G.; Cabanis, E.; Bories, J.; Comar, D.; Castaigne, P.

    1982-09-01

    Positron emission tomography (PET) allows in vivo measurement of local cerebral blood flow (1CBF), oxygen consumption rate (1CMRO 2 ) and glucose utilisation (1CMRG1c) in man. Although 1CMRG1c is accessible in animals, this is not the case for 1CMRO 2 , an excellent index of local functional state. PET imaging of the local interrelationship of CBF and metabolism in completed ischemic stroke has attracted considerable interest because of its potential to differentiate irreversibly damaged from viable tissue on the basis of the CBF- metabolism patterns. Several qualitative or semi-quantitative pioneering studies provided a limited insight into this question, while the single truly quantitative study was only briefly reported. We report here a detailed study of the local CBF-CMRO 2 quantitative patterns in irreversibly infarcted brain regions

  14. Counts and colors of faint galaxies

    International Nuclear Information System (INIS)

    Kron, R.G.

    1980-01-01

    The color distribution of faint galaxies is an observational dimension which has not yet been fully exploited, despite the important constraints obtainable for galaxy evolution and cosmology. Number-magnitude counts alone contain very diluted information about the state of things because galaxies from a wide range in redshift contribute to the counts at each magnitude. The most-frequently-seen type of galaxy depends on the luminosity function and the relative proportions of galaxies of different spectral classes. The addition of color as a measured quantity can thus considerably sharpen the interpretation of galaxy counts since the apparent color depends on the redshift and rest-frame spectrum. (Auth.)

  15. Multiscale analysis of heart rate dynamics: entropy and time irreversibility measures.

    Science.gov (United States)

    Costa, Madalena D; Peng, Chung-Kang; Goldberger, Ary L

    2008-06-01

    Cardiovascular signals are largely analyzed using traditional time and frequency domain measures. However, such measures fail to account for important properties related to multiscale organization and non-equilibrium dynamics. The complementary role of conventional signal analysis methods and emerging multiscale techniques, is, therefore, an important frontier area of investigation. The key finding of this presentation is that two recently developed multiscale computational tools--multiscale entropy and multiscale time irreversibility--are able to extract information from cardiac interbeat interval time series not contained in traditional methods based on mean, variance or Fourier spectrum (two-point correlation) techniques. These new methods, with careful attention to their limitations, may be useful in diagnostics, risk stratification and detection of toxicity of cardiac drugs.

  16. Clean Hands Count

    Medline Plus

    Full Text Available ... is starting stop Loading... Watch Queue Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos ... empower patients to play a role in their care by asking or reminding healthcare providers to clean ...

  17. Reversible and irreversible deactivation of Cu-CHA NH3-SCR catalysts by SO2 and SO3

    DEFF Research Database (Denmark)

    Hammershøi, Peter S.; Jangjou, Yasser; Epling, William S.

    2018-01-01

    be divided into two parts: a reversible deactivation that is restored by the regeneration treatment, and an irreversible part. The irreversible deactivation does not affect the activation energy for NH3-SCR and display a 1:1 correlation with the S-content, consistent with deactivation by Cu-sulfate formation...... is always higher when exposed at 200 °C than at 550 °C, and in wet conditions, compared to a dry feed. The deactivation is predominantly reversible, making regeneration at 550 °C a realistic approach to handle S-poisoning in exhaust systems....

  18. Cerenkov counting and Cerenkov-scintillation counting with high refractive index organic liquids using a liquid scintillation counter

    Energy Technology Data Exchange (ETDEWEB)

    Wiebe, L I; Helus, F; Maier-Borst, W [Deutsches Krebsforschungszentrum, Heidelberg (Germany, F.R.). Inst. fuer Nuklearmedizin

    1978-06-01

    /sup 18/F and /sup 14/C radioactivity was measured in methyl salicylate (MS), a high refractive index hybrid Cherenkov-scintillation generating medium, using a liquid scintillation counter. At concentrations of up to 21.4%, in MS, dimethyl sulfoxide (DMSO) quenched /sup 14/C fluorescence, and with a 10-fold excess of DMSO over MS, /sup 18/F count rates were reduced below that for DMSO alone, probably as a result of concentration-independent self-quenching due to 'dark-complex' formation. DMSO in lower concentrations did not reduce the counting efficiency of /sup 18/F in MS. Nitrobenzene was a concentration-dependent quencher for both /sup 14/C and /sup 18/F in MS. Chlorobenzene (CB) and DMSO were both found to be weak Cherenkov generators with /sup 18/F. Counting efficiencies for /sup 18/F in MS, CB, and DMSO were 50.3, 7.8 and 4.3% respectively in the coincidence counting mode, and 58.1, 13.0 and 6.8% in the singles mode. /sup 14/C efficiencies were 14.4 and 22.3% for coincidence and singles respectively, and 15.3 and 42.0% using a modern counter designed for coincidence and single photon counting. The high /sup 14/C and /sup 18/F counting efficiency in MS are discussed with respect to excitation mechanism, on the basis of quench and channels ratios changes observed. It is proposed that MS functions as an efficient Cherenkov-scintillation generator for high-energy beta emitters such as /sup 18/F, and as a low-efficiency scintillator for weak beta emitting radionuclides such as /sup 14/C.

  19. Clean Hands Count

    Medline Plus

    Full Text Available ... Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with zero ads? Get YouTube Red. ... 396 views 3:10 Wash 'Em - Hand Hygiene Music Video - Duration: 5:46. Thomas Jefferson University & Jefferson ...

  20. Clean Hands Count

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  1. Clean Hands Count

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  2. Clean Hands Count

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    Full Text Available ... Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with zero ads? Get YouTube Red. ... 786 views 1:36 Wash 'Em - Hand Hygiene Music Video - Duration: 5:46. Jefferson Health 413,702 ...

  3. Clean Hands Count

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  4. Clean Hands Count

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  6. Clean Hands Count

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  9. Clean Hands Count

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  10. Clean Hands Count

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    Full Text Available ... Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with zero ads? Get YouTube Red. ... 384 views 1:19 Wash 'Em - Hand Hygiene Music Video - Duration: 5:46. Thomas Jefferson University & Jefferson ...

  11. Clean Hands Count

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    Full Text Available ... Queue __count__/__total__ It’s YouTube. Uninterrupted. Loading... Want music and videos with zero ads? Get YouTube Red. ... 460 views 3:10 Wash 'Em - Hand Hygiene Music Video - Duration: 5:46. Thomas Jefferson University & Jefferson ...

  12. Clean Hands Count

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  13. Clean Hands Count

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  14. Development of a mobile application for manual traffic counts

    Directory of Open Access Journals (Sweden)

    Ghanim Mohammad

    2017-01-01

    Full Text Available The use of technology in performing traffic counts has become widely used by many transportation agencies and private sectors. Different technologies have been employed to perform such counts, such as inductive loops, image processing, Bluetooth technologies, and laser and infrared technologies. However, the use of these advanced technologies come with extra cost to develop, install, and maintain. While the use of advanced technologies provide reliable traffic counts and vehicle classifications data, the use of manual traffic is an inevitable task. Manual traffic counts can serve different purposes, such as performing quality control or conducting short-term traffic survey. Manual traffic counts are usually conducted with the use of the traditional paper-and-pencil approach or the use of hand-held devices that are specifically developed to assess performing manual traffic counts. In this paper, the development of a mobile app that can be used to assist those who need to perform manual traffic counts. The app can be used by many public agencies, private sectors, and college students to collect their traffic data. It also provides users with the capabilities of sharing their traffic counts instantly, where traffic counts can be extracted and processed quickly by other parties.

  15. Low photon count based digital holography for quadratic phase cryptography.

    Science.gov (United States)

    Muniraj, Inbarasan; Guo, Changliang; Malallah, Ra'ed; Ryle, James P; Healy, John J; Lee, Byung-Geun; Sheridan, John T

    2017-07-15

    Recently, the vulnerability of the linear canonical transform-based double random phase encryption system to attack has been demonstrated. To alleviate this, we present for the first time, to the best of our knowledge, a method for securing a two-dimensional scene using a quadratic phase encoding system operating in the photon-counted imaging (PCI) regime. Position-phase-shifting digital holography is applied to record the photon-limited encrypted complex samples. The reconstruction of the complex wavefront involves four sparse (undersampled) dataset intensity measurements (interferograms) at two different positions. Computer simulations validate that the photon-limited sparse-encrypted data has adequate information to authenticate the original data set. Finally, security analysis, employing iterative phase retrieval attacks, has been performed.

  16. SUMS Counts-Related Projects

    Data.gov (United States)

    Social Security Administration — Staging Instance for all SUMs Counts related projects including: Redeterminations/Limited Issue, Continuing Disability Resolution, CDR Performance Measures, Initial...

  17. Defect dependence of the irreversibility line in Bi2Sr2CaCu2O8 single crystals

    Science.gov (United States)

    Lombardo, L. W.; Mitzi, D. B.; Kapitulnik, A.; Leone, A.

    1992-09-01

    The c-axis irreversibility line (IL) of pristine single-crystal Bi2Sr2CaCu2O8 is shown to exhibit three regimes: For fields less than 0.1 T, it obeys a power law, Hirr=H0(1-Tirr/Tc)μ, where μ and H0 vary with Tc. For fields greater than 2 T, the IL becomes linear with a slope of 0.7 T/K. For intermediate fields, there is a crossover region, which corresponds to the onset of collective vortex behavior. Defects produced by proton irradiation shift the IL in all three regimes: The high-field regime moves to higher temperatures, the low-field regime moves to lower temperatures, and the crossover to collective behavior becomes obscured. A maximal increase in the irreversibility temperature in the high-field regime is found to occur at a defect density of nearly one defect per vortex core disk.

  18. Change-Point Methods for Overdispersed Count Data

    National Research Council Canada - National Science Library

    Wilken, Brian A

    2007-01-01

    .... Although the Poisson model is often used to model count data, the two-parameter gamma-Poisson mixture parameterization of the negative binomial distribution is often a more adequate model for overdispersed count data...

  19. Resolution of Loschmidt's paradox: The origin of irreversible behavior in reversible atomistic dynamics

    International Nuclear Information System (INIS)

    Holian, B.L.; Hoover, W.G.; Posch, H.A.

    1987-01-01

    We show that Nosromane-bar mechanics provides a link between computer simulations of nonequilibrium processes and real-world experiments. Reversible Nose-bar equations of motion, when used to constrain non- equilibrium boundary regions, generate stable dissipative behavior within an adjoining bulk sample governed by Newton's equations of motion. Thus, irreversible behavior consistent with the second law of thermodynamics arises from completely reversible microscopic motion. Loschmidt's reversibility paradox is surmounted by this Nose-bar-Newton system, because the steady-state nonequilibrium probability density in the many-body phase space is confined to a zero-volume attractor

  20. Ac irreversibility line of bismuth-based high temperature superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Mehdaoui, A. [Laboratoire de Physique et de Spectroscopie Electronique, URA 1435 Faculte des Sciences, Universite de Haute Alsace 4, rue des Freres Lumiere, 68093 Mulhouse Cedex (France); Beille, J. [Laboratoire Louis Neel, CNRS, BP 166, 38042 Grenoble Cedex 9 (France); Berling, D.; Loegel, B. [Laboratoire de Physique et de Spectroscopie Electronique, URA 1435 Faculte des Sciences, Universite de Haute Alsace 4, rue des Freres Lumiere, 68093 Mulhouse Cedex (France); Noudem, J.G.; Tournier, R. [EPM-MATFORMAG, Laboratoire dElaboration par Procede Magnetique, CNRS, BP 166, 38042 Grenoble Cedex 9 (France)

    1997-09-01

    We discuss the magnetic properties of lead doped Bi-2223 bulk samples obtained through combined magnetic melt texturing and hot pressing (MMTHP). The ac complex susceptibility measurements are achieved over a broad ac field range (1 Oe{lt}h{sub ac}{lt}100 Oe) and show highly anisotropic properties. The intergranular coupling is improved in the direction perpendicular to the applied stress and magnetic field direction, and an intragranular loss peak is observed for the first time. A comparison is made with other bismuth-based compounds and it is shown that the MMTHP process shifts the ac irreversibility line (ac IL) toward higher fields. It is also shown that all the ac IL{close_quote}s for quasi 2D bismuth-based compounds show a nearly quadratic temperature dependence and deviate therefore strongly from the linear behavior observed in quasi 3D compounds and expected from a critical state model.{copyright} {ital 1997 Materials Research Society.}

  1. Leveraging multiple datasets for deep leaf counting

    OpenAIRE

    Dobrescu, Andrei; Giuffrida, Mario Valerio; Tsaftaris, Sotirios A

    2017-01-01

    The number of leaves a plant has is one of the key traits (phenotypes) describing its development and growth. Here, we propose an automated, deep learning based approach for counting leaves in model rosette plants. While state-of-the-art results on leaf counting with deep learning methods have recently been reported, they obtain the count as a result of leaf segmentation and thus require per-leaf (instance) segmentation to train the models (a rather strong annotation). Instead, our method tre...

  2. Detection limits for radioanalytical counting techniques

    International Nuclear Information System (INIS)

    Hartwell, J.K.

    1975-06-01

    In low-level radioanalysis it is usually necessary to test the sample net counts against some ''Critical Level'' in order to determine if a given result indicates detection. This is an interpretive review of the work by Nicholson (1963), Currie (1968) and Gilbert (1974). Nicholson's evaluation of three different computational formulas for estimation of the ''Critical Level'' is discussed. The details of Nicholson's evaluation are presented along with a basic discussion of the testing procedures used. Recommendations are presented for calculation of confidence intervals, for reporting of analytical results, and for extension of the derived formula to more complex cases such as multiple background counts, multiple use of a single background count, and gamma spectrometric analysis

  3. Counts of low-Redshift SDSS quasar candidates

    International Nuclear Information System (INIS)

    Zeljko Ivezic

    2004-01-01

    We analyze the counts of low-redshift quasar candidates selected using nine-epoch SDSS imaging data. The co-added catalogs are more than 1 mag deeper than single-epoch SDSS data, and allow the selection of low-redshift quasar candidates using UV-excess and also variability techniques. The counts of selected candidates are robustly determined down to g = 21.5. This is about 2 magnitudes deeper than the position of a change in the slope of the counts reported by Boyle (and others) (1990, 2000) for a sample selected by UV-excess, and questioned by Hawkins and Veron (1995), who utilized a variability-selected sample. Using SDSS data, we confirm a change in the slope of the counts for both UV-excess and variability selected samples, providing strong support for the Boyle (and others) results

  4. Liquid scintillation counting of chlorophyll

    International Nuclear Information System (INIS)

    Fric, F.; Horickova, B.; Haspel-Horvatovic, E.

    1975-01-01

    A precise and reproducible method of liquid scintillation counting was worked out for measuring the radioactivity of 14 C-labelled chlorophyll a and chlorophyll b solutions without previous bleaching. The spurious count rate caused by luminescence of the scintillant-chlorophyll system is eliminated by using a suitable scintillant and by measuring the radioactivity at 4 to 8 0 C after an appropriate time of dark adaptation. Bleaching of the chlorophyll solutions is necessary only for measuring of very low radioactivity. (author)

  5. Electro-Kinetic Pumping with Slip Irreversibility in Heat Exchange of CSP-Powered Bio-Digester Assemblies

    OpenAIRE

    Ogedengbe, Emmanuel; Rosen, Marc

    2012-01-01

    Parametric studies of the effects of slip irreversibility in concentrating solar power (CSP)-powered bio-digester assemblies are investigated. Complexities regarding the identification of the appropriate electro-kinetic phenomena for certain electrolyte phases are reviewed. The application of exergy analysis to the design of energy conversion devices, like solar thermal collectors, for the required heat of formation in a downdraft waste food bio-digester, is discussed. Thermal management in t...

  6. Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

    Directory of Open Access Journals (Sweden)

    Scarlet eGallegos

    2015-03-01

    Full Text Available Alpha-synuclein is a presynaptic protein expressed throughout the central nervous system, and it is the main component of Lewy bodies, one of the histopathological features of Parkinson’s disease (PD which is a progressive and irreversible neurodegenerative disorder. The conformational flexibility of α-synuclein allows it to adopt different conformations, i.e. bound to membranes or form aggregates, the oligomers are believed to be the more toxic species. In this review, we will focus on two major features of α-synuclein, transmission and toxicity that could help to understand the pathological characteristics of PD. One important feature of α-synuclein is its ability to be transmitted from neuron to neuron using mechanisms such as endocytosis, plasma membrane penetration or through exosomes, thus propagating the Lewy body pathology to different brain regions thereby contributing to the progressiveness of PD. The second feature of α-synuclein is that it confers cytotoxicity to recipient cells, principally when it is in an oligomeric state. This form causes mitochondrial dysfunction, endoplasmic reticulum stress, oxidative stress, proteasome impairment, disruption of plasma membrane and pore formation, and lead to apoptosis pathway activation and consequent cell death. The complexity of α-synuclein oligomerization and formation of toxic species could be a major factor for the irreversibility of PD and could also explain the lack of successful therapies to halt the disease.

  7. Evaluating the periapical status of teeth with irreversible pulpitis by using cone-beam computed tomography scanning and periapical radiographs.

    Science.gov (United States)

    Abella, Francesc; Patel, Shanon; Duran-Sindreu, Fernando; Mercadé, Montse; Bueno, Rufino; Roig, Miguel

    2012-12-01

    The purpose of this study was to compare the prevalence of apical periodontitis (AP) on individual roots of teeth with irreversible pulpitis viewed with periapical (PA) radiographs and cone-beam computed tomography (CBCT) scans. PA radiographs and CBCT scans were taken of 138 teeth in 130 patients diagnosed with irreversible pulpitis (symptomatic and asymptomatic). Two calibrated examiners assessed the presence or absence of AP lesions by analyzing the PA and CBCT images. A consensus was reached in the event of any disagreement. The data were analyzed using the hypothesis test, and significance was set at P ≤ .05. Three hundred seven paired roots were assessed with both PA and CBCT images. A comparison of the 307 paired roots revealed that AP lesions were present in 10 (3.3%) and absent in 297 (96.7%) pairs of roots when assessed with PA radiography. When the same 307 sets of roots were assessed with CBCT scans, AP lesions were present in 42 (13.7%) and absent in 265 (86.3%) paired roots. The prevalence of AP lesions detected with CBCT was significantly higher in the symptomatic group compared with the asymptomatic group (P < .05). An additional 22 roots were identified with CBCT alone. The present study highlights the advantages of using CBCT for detecting AP lesions, especially in teeth with symptomatic irreversible pulpitis. Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. Radiation Counting System Software Using Visual Basic

    International Nuclear Information System (INIS)

    Nanda Nagara; Didi Gayani

    2009-01-01

    It has been created a Gamma Radiation Counting System using interface card, which paired with Personal Computer (PC) and operated by the Visual Basic program. The program was set through varied menu selections such as ”Multi Counting” , ”Counting and Record” and ”View Data”. An interface card for data acquisition was formed by using AMD9513 components as a counter and timer which can be programmed. This counting system was tested and used in waste facility in PTNBR and the result is quite good. (author)

  9. X-tip intraosseous injection system as a primary anesthesia for irreversible pulpitis of posterior mandibular teeth: A randomized clinical trail.

    Science.gov (United States)

    Razavian, Hamid; Kazemi, Shantia; Khazaei, Saber; Jahromi, Maryam Zare

    2013-03-01

    Successful anesthesia during root canal therapy may be difficult to obtain. Intraosseous injection significantly improves anesthesia's success as a supplemental pulpal anesthesia, particularly in cases of irreversible pulpitis. The aim of this study was to compare the efficacy of X-tip intraosseous injection and inferior alveolar nerve (IAN) block in primary anesthesia for mandibular posterior teeth with irreversible pulpitis. Forty emergency patients with an irreversible pulpitis of mandibular posterior teeth were randomly assigned to receive either intraosseous injection using the X-tip intraosseous injection system or IAN block as the primary injection method for pulpal anesthesia. Pulpal anesthesia was evaluated using an electric pulp tester and endo ice at 5-min intervals for 15 min. Anesthesia's success or failure rates were recorded and analyzed using SPSS version 12 statistical software. Success or failure rates were compared using a Fisher's exact test, and the time duration for the onset of anesthesia was compared using Mann-Whitney U test. P Intraosseous injection system resulted in successful anesthesia in 17 out of 20 patients (85%). Successful anesthesia was achieved with the IAN block in 14 out of 20 patients (70%). However, the difference (15%) was not statistically significant (P = 0.2). Considering the relatively expensive armamentarium, probability of penetrator separation, temporary tachycardia, and possibility of damage to root during drilling, the authors do not suggest intraosseous injection as a suitable primary technique.

  10. Alaska Steller Sea Lion Pup Count Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database contains counts of Steller sea lion pups on rookeries in Alaska made between 1961 and 2015. Pup counts are conducted in late June-July. Pups are...

  11. Anesthetic efficacy of the supplemental X-tip intraosseous injection using 4% articaine with 1:100,000 adrenaline in patients with irreversible pulpitis: An in vivo study

    Science.gov (United States)

    Bhuyan, Atool Chandra; Latha, Satheesh Sasidharan; Jain, Shefali; Kataki, Rubi

    2014-01-01

    Introduction: Pain management remains the utmost important qualifying criteria in minimizing patient agony and establishing a strong dentist–patient rapport. Symptomatic irreversible pulpitis is a painful condition necessitating immediate attention and supplemental anesthetic techniques are often resorted to in addition to conventional inferior alveolar nerve block. Aim: The purpose of the study was to evaluate the anesthetic efficacy of X-tip intraosseous injection in patients with symptomatic irreversible pulpitis, in mandibular posterior teeth, using 4% Articaine with 1:100,000 adrenaline as local anesthetic, when the conventional inferior alveolar nerve block proved ineffective. Materials and Methods: X-tip system was used to administer 1.7 ml of 4% articaine with 1:100,000 adrenaline in 30 patients diagnosed with irreversible pulpitis of mandibular posterior teeth with moderate to severe pain on endodontic access after administration of an inferior alveolar nerve block. Results: The results of the study showed that 25 X-tip injections (83.33%) were successful and 5 X-tip injections (16.66%) were unsuccessful. Conclusion: When the inferior alveolar nerve block fails to provide adequate pulpal anesthesia, X-tip system using 4% articaine with 1:100,000 adrenaline was successful in achieving pulpal anesthesia in patients with irreversible pulpitis. PMID:25506137

  12. Photon counting and fluctuation of molecular movement

    International Nuclear Information System (INIS)

    Inohara, Koichi

    1978-01-01

    The direct measurement of the fluctuation of molecular motions, which provides with useful information on the molecular movement, was conducted by introducing photon counting method. The utilization of photon counting makes it possible to treat the molecular system consisting of a small number of molecules like a radioisotope in the detection of a small number of atoms, which are significant in biological systems. This method is based on counting the number of photons of the definite polarization emitted in a definite time interval from the fluorescent molecules excited by pulsed light, which are bound to the marked large molecules found in a definite spatial region. Using the probability of finding a number of molecules oriented in a definite direction in the definite spatial region, the probability of counting a number of photons in a definite time interval can be calculated. Thus the measurable count rate of photons can be related with the fluctuation of molecular movement. The measurement was carried out under the condition, in which the probability of the simultaneous arrival of more than two photons at a detector is less than 1/100. As the experimental results, the resolving power of photon-counting apparatus, the frequency distribution of the number of photons of some definite polarization counted for 1 nanosecond are shown. In the solution, the variance of the number of molecules of 500 on the average is 1200, which was estimated from the experimental data by assuming normal distribution. This departure from the Poisson distribution means that a certain correlation does exist in molecular movement. In solid solution, no significant deviation was observed. The correlation existing in molecular movement can be expressed in terms of the fluctuation of the number of molecules. (Nakai, Y.)

  13. Adaptive and automatic red blood cell counting method based on microscopic hyperspectral imaging technology

    Science.gov (United States)

    Liu, Xi; Zhou, Mei; Qiu, Song; Sun, Li; Liu, Hongying; Li, Qingli; Wang, Yiting

    2017-12-01

    Red blood cell counting, as a routine examination, plays an important role in medical diagnoses. Although automated hematology analyzers are widely used, manual microscopic examination by a hematologist or pathologist is still unavoidable, which is time-consuming and error-prone. This paper proposes a full-automatic red blood cell counting method which is based on microscopic hyperspectral imaging of blood smears and combines spatial and spectral information to achieve high precision. The acquired hyperspectral image data of the blood smear in the visible and near-infrared spectral range are firstly preprocessed, and then a quadratic blind linear unmixing algorithm is used to get endmember abundance images. Based on mathematical morphological operation and an adaptive Otsu’s method, a binaryzation process is performed on the abundance images. Finally, the connected component labeling algorithm with magnification-based parameter setting is applied to automatically select the binary images of red blood cell cytoplasm. Experimental results show that the proposed method can perform well and has potential for clinical applications.

  14. Study of the anesthetic efficacy of inferior alveolar nerve block using articaine in irreversible pulpitis.

    Science.gov (United States)

    Ahmad, Zeeshan H; Ravikumar, H; Karale, Rupali; Preethanath, R S; Sukumaran, Anil

    2014-01-01

    The purpose of this study was to determine the anesthetic efficacy of inferior alveolar nerve block (IANB) using 4% articaine and 2% lidocaine supplemented with buccal infiltration. Forty five patients, diagnosed with irreversible pulpitis of a mandibular posterior tooth were included in the study. The first group of 15 patients received 2% lidocaine with 1:200000 epinephrine, the second group 2% lidocaine with 1: 80,000 epinephrine and the third group of 15 subjects received 4% articaine with 1:100000 epinephrine. During the access cavity preparation those patients who complained of pain received an additional buccal infiltration. The percentage of subjects who got profound anesthesia and failure to achieve anesthesia were calculated and tabulated using a visual analog scale. The results revealed that 87% of subjects who received 4% Articaine with 1:100,000 epinephrine got satisfactory anesthesia with inferior alveolar nerve block alone. Only 2 (13%) subjects received an additional buccal infiltration and none of the patients failed to obtain complete anesthesia with articaine. In comparison only 40% of subjects got complete anesthesia with 2% lidocaine with 1:200000 and 60% with 2% lidocaine with 1:80,000. It can be concluded that 4% articaine can be used effectively for obtaining profound anesthesia for endodontic procedures in patients with irreversible pulpitis.

  15. Comparative study of irreversibilities in an aqua-ammonia absorption refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Ataer, O E [Gazi Univ., Ankara (TR). Mechanical Engineering Dept.; Gogus, Y [Middle East Technical Univ., Ankara (Turkey)

    1991-03-01

    Irreversibilities in components of an aqua-ammonia absorption refrigeration system (ARS) have been determined by second law analysis. The components of the ARS are as follows: condenser, evaporator, absorber, generator, pump, expansion valves, mixture heat exchanger and refrigerant heat exchanger. It is assumed that the ammonia concentration at the generator exit is, independent of the other parameters, equal to 0.999 and at the evaporator exit the gas is saturated vapour. Pressure losses between the generator and condenser, and the evaporator and absorber are taken into consideration. In the results the dimensionless exergy loss of each component, the exergetic coefficient of performance, the coefficient of performance and the circulation ratio are given graphically for each different generator, evaporator, condenser and absorber temperature. (author).

  16. Current status of liquid scintillation counting

    International Nuclear Information System (INIS)

    Klingler, G.W.

    1981-01-01

    Scintillation counting of alpha particles has been used since the turn of the century. The advent of pulse shape discrimination has made this method of detection accurate and reliable. The history, concepts and development of scintillation counting and pulse shape discrimination are discussed. A brief look at the ongoing work in the consolidation of components now used for pulse shape discrimination is included

  17. ESTIMATION OF IRREVERSIBLE DAMAGEABILITY AT FATIGUE OF CARBON STEEL

    Directory of Open Access Journals (Sweden)

    I. O. Vakulenko

    2014-04-01

    Full Text Available Purpose. Damageability estimation of carbon steel in the conditions of cyclic loading. Methodology. The steel fragments of railway wheel rim and rail head served as material for research with chemical composition 0.65 % С, 0.67 % Mn, 0.3 % Si, 0.027 % P, 0.028 % S и 0.7 % C, 0.82 % Mn, 0.56 % Si, 0.025 % P, 0.029 % S accordingly. The microstructure of tested steels corresponded to the state of metal after a hot plastic deformation. The fatigue research was conducted in the conditions of symmetric bend using the proof-of-concept machine of type «Saturn-10». Full Wohler diagrams and the lines corresponding to forming of sub-and micro cracks were constructed. The distribution analysis of internal stresses in the metal under cyclic loading was carried out using the microhardness tester of PMT-3 type.Findings. On the basis of fatigue curves for high-carbon steels analysis the positions of borders dividing the areas of convertible and irreversible damages were determined. The article shows that with the growth of carbon concentration in the steel at invariability of the structural state an increase of fatigue limit is observed. At the same time the acceleration of processes, which determine transition terms from the stage of forming of submicrocracks to the microcracks occurs. The research of microhardness distribution in the metal after destruction confirmed the nature of carbon amount influence on the carbon steel characteristics. Originality. Regardless on the stages of breakdown site forming the carbon steels behavior at a fatigue is determined by the ration between the processes of strengthening and softening. At a cyclic loading the heterogeneity of internal stresses distribution decreases with the increase of distance from the destruction surface. Analysis of metal internal restructuring processes at fatigue loading made it possible to determine that at the stages prior to incubation period in the metal microvolumes the cells are already

  18. Is the Use of Dexamethasone Effective in Controlling Pain Associated with Symptomatic Irreversible Pulpitis? A Systematic Review.

    Science.gov (United States)

    Nogueira, Brenna M L; Silva, Ludmylla G; Mesquita, Carla R M; Menezes, Sílvio A F; Menezes, Tatiany O A; Faria, Antônio G M; Porpino, Mariana T M

    2018-05-01

    Endodontic pain is a symptom of pulpal and/or periapical inflammation. One strategy for pain reduction is using medications, such as dexamethasone. A definitive protocol for preventing and controlling pain caused by irreversible pulpitis during endodontic treatment has not yet been established. This is a systematic review to answer the following question: is the use of dexamethasone effective in controlling pain associated with symptomatic irreversible pulpitis? This study was registered in the PROSPERO database (CRD42017058704), and Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement recommendations were followed. MEDLINE, Scopus, ScienceDirect, Web of Science, Latin American Caribbean Health Sciences Literature, Cochrane Library, and Google Scholar databases were used in our research. No restrictions were applied to dates or language of publication. All records identified electronically were organized and evaluated by 2 independent authors, and, in case of doubt, a third author made the decision. The Cochrane Collaboration tool was used. The data were analyzed with RevMan 5 software (The Cochrane Collaboration, Copenhagen, Denmark), and data from eligible studies were dichotomous (with and without pain). A total of 4825 studies were identified. After screening, 523 studies were selected, and, after careful evaluation, only 5 articles remained. All meta-analyses revealed a global effect (P < .05, P < .05, and P < .05), which means that 4 mg dexamethasone helps relieve pain, sometimes for up to 8, 12, and 24 hours. The pain felt by patients diagnosed with symptomatic irreversible pulpitis may be alleviated by administering 4 mg dexamethasone either by mouth or through intraligamentary and mainly supraperiosteal injections into the root canal for up to 24 hours. Copyright © 2018 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  19. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes

    Science.gov (United States)

    Dubovsky, Jason A.; Beckwith, Kyle A.; Natarajan, Gayathri; Woyach, Jennifer A.; Jaglowski, Samantha; Zhong, Yiming; Hessler, Joshua D.; Liu, Ta-Ming; Chang, Betty Y.; Larkin, Karilyn M.; Stefanovski, Matthew R.; Chappell, Danielle L.; Frissora, Frank W.; Smith, Lisa L.; Smucker, Kelly A.; Flynn, Joseph M.; Jones, Jeffrey A.; Andritsos, Leslie A.; Maddocks, Kami; Lehman, Amy M.; Furman, Richard; Sharman, Jeff; Mishra, Anjali; Caligiuri, Michael A.; Satoskar, Abhay R.; Buggy, Joseph J.; Muthusamy, Natarajan; Johnson, Amy J.

    2013-01-01

    Given its critical role in T-cell signaling, interleukin-2–inducible kinase (ITK) is an appealing therapeutic target that can contribute to the pathogenesis of certain infectious, autoimmune, and neoplastic diseases. Ablation of ITK subverts Th2 immunity, thereby potentiating Th1-based immune responses. While small-molecule ITK inhibitors have been identified, none have demonstrated clinical utility. Ibrutinib is a confirmed irreversible inhibitor of Bruton tyrosine kinase (BTK) with outstanding clinical activity and tolerability in B-cell malignancies. Significant homology between BTK and ITK alongside in silico docking studies support ibrutinib as an immunomodulatory inhibitor of both ITK and BTK. Our comprehensive molecular and phenotypic analysis confirms ITK as an irreversible T-cell target of ibrutinib. Using ibrutinib clinical trial samples along with well-characterized neoplastic (chronic lymphocytic leukemia), parasitic infection (Leishmania major), and infectious disease (Listeria monocytogenes) models, we establish ibrutinib as a clinically relevant and physiologically potent ITK inhibitor with broad therapeutic utility. This trial was registered at www.clinicaltrials.gov as #NCT01105247 and #NCT01217749. PMID:23886836

  20. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.

    Science.gov (United States)

    Dubovsky, Jason A; Beckwith, Kyle A; Natarajan, Gayathri; Woyach, Jennifer A; Jaglowski, Samantha; Zhong, Yiming; Hessler, Joshua D; Liu, Ta-Ming; Chang, Betty Y; Larkin, Karilyn M; Stefanovski, Matthew R; Chappell, Danielle L; Frissora, Frank W; Smith, Lisa L; Smucker, Kelly A; Flynn, Joseph M; Jones, Jeffrey A; Andritsos, Leslie A; Maddocks, Kami; Lehman, Amy M; Furman, Richard; Sharman, Jeff; Mishra, Anjali; Caligiuri, Michael A; Satoskar, Abhay R; Buggy, Joseph J; Muthusamy, Natarajan; Johnson, Amy J; Byrd, John C

    2013-10-10

    Given its critical role in T-cell signaling, interleukin-2-inducible kinase (ITK) is an appealing therapeutic target that can contribute to the pathogenesis of certain infectious, autoimmune, and neoplastic diseases. Ablation of ITK subverts Th2 immunity, thereby potentiating Th1-based immune responses. While small-molecule ITK inhibitors have been identified, none have demonstrated clinical utility. Ibrutinib is a confirmed irreversible inhibitor of Bruton tyrosine kinase (BTK) with outstanding clinical activity and tolerability in B-cell malignancies. Significant homology between BTK and ITK alongside in silico docking studies support ibrutinib as an immunomodulatory inhibitor of both ITK and BTK. Our comprehensive molecular and phenotypic analysis confirms ITK as an irreversible T-cell target of ibrutinib. Using ibrutinib clinical trial samples along with well-characterized neoplastic (chronic lymphocytic leukemia), parasitic infection (Leishmania major), and infectious disease (Listeria monocytogenes) models, we establish ibrutinib as a clinically relevant and physiologically potent ITK inhibitor with broad therapeutic utility. This trial was registered at www.clinicaltrials.gov as #NCT01105247 and #NCT01217749.