WorldWideScience

Sample records for favourability studies federal

  1. 76 FR 5787 - Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant...

    Science.gov (United States)

    2011-02-02

    ... Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant Programs... Perkins Loan, Federal Work-Study (FWS), and Federal Supplemental Educational Opportunity Grant (FSEOG... Federal Perkins Loan Program, Federal Work-Study Program, and Federal Supplemental Educational...

  2. 75 FR 12217 - Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant...

    Science.gov (United States)

    2010-03-15

    ... Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant programs... Perkins Loan, Federal Work-Study (FWS), and Federal Supplemental Educational Opportunity Grant (FSEOG.... (2) General Provisions for the Federal Perkins Loan Program, Federal Work-Study Program, and...

  3. 77 FR 4547 - Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant...

    Science.gov (United States)

    2012-01-30

    ... Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant Programs... requests and documents from postsecondary institutions for the Federal Perkins Loan, Federal Work-Study.... (2) General Provisions for the Federal Perkins Loan Program, Federal Work-Study Program, and...

  4. 78 FR 14776 - Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant...

    Science.gov (United States)

    2013-03-07

    ... Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant Programs... requests and documents from postsecondary institutions for the Federal Perkins Loan, Federal Work-Study..., Federal Work-Study Program, and Federal Supplemental Educational Opportunity Grant Program, 34 CFR...

  5. Study of federal microwave standards

    Energy Technology Data Exchange (ETDEWEB)

    David, L.

    1980-08-01

    Present and future federal regulatory processes which may impact the permissible levels of microwave radiation emitted by the SPS Microwave Power Transmission (MPTS) were studied. An historical development of US occupational and public microwave standards includes an overview of Western and East European philosophies of environmental protection and neurophysiology which have led to the current widely differing maximum permissible exposure limits to microwaves. The possible convergence of microwave standards is characterized by a lowering of Western exposure levels while Eastern countries consider standard relaxation. A trend toward stricter controls on activities perceived as harmful to public health is under way as is interest in improving the federal regulatory process. Particularly relevant to SPS is the initiation of long-term, low-level microwave exposure programs. Coupled with new developments in instrumentation and dosimetry, the results from chronic exposure program and population exposure studies could be expected within the next five to ten years. Also discussed is the increasing public concern that rf energy is yet another hazardous environmental agent.

  6. Favourable outcome after peripartum cardiomyopathy: a ten-year study on peripartum cardiomyopathy in a university hospital.

    Science.gov (United States)

    Chee, Kok-Han

    2013-01-01

    Peripartum cardiomyopathy (PPCM) is an uncommon form of congestive heart failure, affecting obstetric patients around the time of delivery. The epidemiology of PPCM is infrequently reported. This study was undertaken to define the prevalence, presentation and outcome of PPCM among women giving birth in a teaching hospital in Malaysia. A retrospective case record analysis was conducted on all patients admitted and diagnosed with PPCM at the University Malaya Medical Centre, Kuala Lumpur, Malaysia, from 1 January 2000 to 31 December 2009. All deliveries were undertaken in the same hospital. A total of 12 patients were diagnosed with PPCM during the ten-year study period. The prevalence of PPCM was 2.48 in 100,000 (1 in 40,322) live births. Nine women were diagnosed with PPCM within five months of delivery. Three women had twin pregnancies. There was one death in the group (mortality rate 8.3%). The mean left ventricular ejection fraction at the time of diagnosis was 28.9% ± 8.5% (range 15%-40%). Following the index event, left ventricular function normalised in six of the nine patients (66.7%) who underwent subsequent echocardiography one year later. All patients were treated with standard heart failure therapy. Two patients with normalised left ventricular function had subsequent pregnancies - one pregnancy was terminated at seven weeks and the other patient delivered uneventfully at full term. PPCM is uncommon. The outcome in our series was favourable, with 66.7% of patients with PPCM recovering their left ventricular function. The mortality rate was 8.3%.

  7. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study

    NARCIS (Netherlands)

    Boers, I.; Muskiet, F.A.J.; Berkelaar, E.; Schut, E.; Penders, R.; Hoenderdos, K.; Jong, de M.C.; Wichers, H.J.

    2014-01-01

    Background The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a

  8. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome : a randomized controlled pilot-study

    NARCIS (Netherlands)

    Boers, Inge; Muskiet, Frits A. J.; Berkelaar, Evert; Schut, Erik; Penders, Ria; Hoenderdos, Karine; Wichers, Harry J.; Jong, Miek C.

    2014-01-01

    Background: The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a

  9. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome : a randomized controlled pilot-study

    NARCIS (Netherlands)

    Boers, Inge; Muskiet, Frits A. J.; Berkelaar, Evert; Schut, Erik; Penders, Ria; Hoenderdos, Karine; Wichers, Harry J.; Jong, Miek C.

    2014-01-01

    Background: The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a Paleolit

  10. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study

    NARCIS (Netherlands)

    Boers, I.; Muskiet, F.A.J.; Berkelaar, E.; Schut, E.; Penders, R.; Hoenderdos, K.; Jong, de M.C.; Wichers, H.J.

    2014-01-01

    Background The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a Paleolith

  11. Favourability: concept, distinctive characteristics and potential usefulness

    Science.gov (United States)

    Acevedo, Pelayo; Real, Raimundo

    2012-07-01

    The idea of analysing the general favourability for the occurrence of an event was presented in 2006 through a mathematical function. However, even when favourability has been used in species distribution modelling, the conceptual framework of this function is not yet well perceived among many researchers. The present paper is conceived for providing a wider and more in-depth presentation of the idea of favourability; concretely, we aimed to clarify both the concept and the main distinctive characteristics of the favourability function, especially in relation to probability and suitability, the most common outputs in species distribution modelling. As the capabilities of the favourability function go beyond species distribution modelling, we also illustrate its usefulness for different research disciplines for which this function remains unknown. In particular, we stressed that the favourability function has potential to be applied in all the cases where the probability of occurrence of an event is analysed, such as, for example, habitat selection or epidemiological studies.

  12. Species Favourability Shift in Europe due to Climate Change: A Case Study for Fagus sylvatica L. and Picea abies (L. Karst. Based on an Ensemble of Climate Models

    Directory of Open Access Journals (Sweden)

    Wolfgang Falk

    2013-01-01

    Full Text Available Climate is the main environmental driver determining the spatial distribution of most tree species at the continental scale. We investigated the distribution change of European beech and Norway spruce due to climate change. We applied a species distribution model (SDM, driven by an ensemble of 21 regional climate models in order to study the shift of the favourability distribution of these species. SDMs were parameterized for 1971–2000, as well as 2021–2050 and 2071–2100 using the SRES scenario A1B and three physiological meaningful climate variables. Growing degree sum and precipitation sum were calculated for the growing season on a basis of daily data. Results show a general north-eastern and altitudinal shift in climatological favourability for both species, although the shift is more marked for spruce. The gain of new favourable sites in the north or in the Alps is stronger for beech compared to spruce. Uncertainty is expressed as the variance of the averaged maps and with a density function. Uncertainty in species distribution increases over time. This study demonstrates the importance of data ensembles and shows how to deal with different outcomes in order to improve impact studies by showing uncertainty of the resulting maps.

  13. Public attitudes to the promotion of genomic crop studies in Japan: correlations between genomic literacy, trust, and favourable attitude.

    Science.gov (United States)

    Ishiyama, Izumi; Tanzawa, Tetsuro; Watanabe, Maiko; Maeda, Tadahiko; Muto, Kaori; Tamakoshi, Akiko; Nagai, Akiko; Yamagata, Zentaro

    2012-05-01

    This study aimed to assess public attitudes in Japan to the promotion of genomic selection in crop studies and to examine associated factors. We analysed data from a nationwide opinion survey. A total of 4,000 people were selected from the Japanese general population by a stratified two-phase sampling method, and 2,171 people participated by post; this survey asked about the pros and cons of crop-related genomic studies promotion, examined people's scientific literacy in genomics, and investigated factors thought to be related to genomic literacy and attitude. The relationships were examined using logistic regression models stratified by gender. Survey results showed that 50.0% of respondents approved of the promotion of crop-related genomic studies, while 6.7% disapproved. No correlation was found between literacy and attitude towards promotion. Trust in experts, belief in science, an interest in genomic studies and willingness to purchase new products correlated with a positive attitude towards crop-related genomic studies.

  14. Excessive alcohol consumption favours high risk polyp or colorectal cancer occurrence among patients with adenomas: a case control study

    OpenAIRE

    Bardou, M; Montembault, S; Giraud, V.; Balian, A; Borotto, E; Houdayer, C.; Capron, F.; Chaput, J-C; Naveau, S

    2002-01-01

    Background and aims: Excessive alcohol consumption is a risk factor for developing colorectal adenomas. This study aimed to investigate the influence of excessive alcohol consumption on the occurrence of high risk polyps (adenoma ≥10 mm, villous component, high grade dysplasia) or colorectal cancer among patients with at least one colonic adenoma.

  15. The Roles and Attributes of the Clinical Teacher that Contribute to Favourable Learning Environments: A Case Study from Physiotherapy

    Directory of Open Access Journals (Sweden)

    DV Ernstzen

    2012-12-01

    Full Text Available The quality of clinical education is dependenton learning experiences. The clinical teacher plays a key role insuccessful clinical education.The aims of the study were to determine which roles and attributesof physiotherapy clinical teachers contribute to a supportiveclinical learning environment according to physiotherapy studentsand their clinical teachers.The study protocol was approved by the Committee for HumanResearch at Stellenbosch University. A qualitative research designwas used. An interview schedule was developed based on existing literature. Data was analyzed using contentanalysis. Data was coded, categorized and conceptualized into key themes and patterns.All third year (n=40 and fourth year (n=40 undergraduate physiotherapy students and their clinical teachers(n=37 were eligible to participate. Semi-structured individual interviews were conducted with a purposivesample consisting of six third-year students, six fourth-year students and six clinical teachers (n=18. Written informedconsent was obtained from all participants prior to the interviews.The teacher as role model and facilitator of learning was emphasised. The attributes of the clinical teacher thatcreated a supportive learning environment were approachability, recognising student abilities and good communicationskills. The value of active involvement and individualism in learning was highlighted.The study confirmed that the clinical teacher is pivotal in the success of a physiotherapy clinical education program.The findings agree with the large body of international literature about supportive clinical learning environments.

  16. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study.

    Science.gov (United States)

    Boers, Inge; Muskiet, Frits Aj; Berkelaar, Evert; Schut, Erik; Penders, Ria; Hoenderdos, Karine; Wichers, Harry J; Jong, Miek C

    2014-10-11

    The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a Paleolithic-type diet and may provide new insights in the pathophysiological mechanisms underlying the metabolic syndrome. In addition, more information on feasibility and designing an innovative dietary research program on the basis of a Palaeolithic-type diet was obtained. Thirty-four subjects, with at least two characteristics of the metabolic syndrome, were randomized to a two weeks Palaeolithic-type diet (n = 18) or an isoenergetic healthy reference diet, based on the guidelines of the Dutch Health Council (n = 14). Thirty-two subjects completed the study. Measures were taken to keep bodyweight stable. As primary outcomes oral glucose tolerance and characteristics of the metabolic syndrome (abdominal circumference, blood pressure, glucose, lipids) were measured. Secondary outcomes were intestinal permeability, inflammation and salivary cortisol. Data were collected at baseline and after the intervention. Subjects were 53.5 (SD9.7) year old men (n = 9) and women (n = 25) with mean BMI of 31.8 (SD5.7) kg/m2. The Palaeolithic-type diet resulted in lower systolic blood pressure (-9.1 mmHg; P = 0.015), diastolic blood pressure (-5.2 mmHg; P = 0.038), total cholesterol (-0.52 mmol/l; P = 0.037), triglycerides (-0.89 mmol/l; P = 0.001) and higher HDL-cholesterol (+0.15 mmol/l; P = 0.013), compared to reference. The number of characteristics of the metabolic syndrome decreased with 1.07 (P = 0.010) upon the Palaeolithic-type diet, compared to reference. Despite efforts to keep bodyweight stable, it decreased in the Palaeolithic group compared to reference (-1.32 kg; P = 0.012). However, favourable effects remained after post-hoc adjustments for this

  17. SYSTEM OF ACTIONS TO FAVOUR THE INTERDISCIPLINARITY IN THE CAREER OF SOCIOCULTURAL STUDIES / SISTEMA DE ACCIONES PARA FAVORECER LA INTERDISCIPLINARIEDAD EN LA CARRERA DE ESTUDIOS SOCIOCULTURALES

    Directory of Open Access Journals (Sweden)

    José Luis Marañón Rodríguez

    Full Text Available To form a more and more integral personality and with a wide vision of the world in that today one is living it is an unavoidable task to have the Cuban educators before yes, in a time characterized by a deep integration of the sciences. The achievement of this implies the elaboration of actions guided to reach a bigger integration among the contents of the subjects that today in day is imparted in the curriculum of the university students and its utility in the practice. For this aim it has decided to conceive the present work, with more emphasis in the interdisciplinarity among the subjects that are imparted in the disciplines History and Cultural Thought and Cuban Culture, corresponding to the Plan D of the career of Degree in Sociocultural Studies, being the main objective of the same one to favour the integration of the contents of this matters through the elaboration of a system of actions, demand of the current Cuban education without which we cannot perfect the teaching process - learning forming a man with a bigger preparation for the life, demand of the current Cuban society. The practical experiences applied in the University of The Tunas and the obtained results justify this proposal.

  18. Delineation of structures favourable to groundwater occurrence employing seismic refraction method — A case study from Tiruvuru, Krishna district, Andhra Pradesh

    Indian Academy of Sciences (India)

    N Sundararajan; Y Srinivas; M Narasimha Chary; G Nandakumar; A Hanmantha Chary

    2004-09-01

    The contacts associated with an outlier in biotite gneiss and sandstones near Tiruvuru, Krishna district, Andhra Pradesh which are generally favourable for groundwater occurrence were investigated employing refraction seismic method. Results were examined by correlating the signals with local geology, bore well data and other available information in order to improve the reliability of interpretation.

  19. Ichneumon wasp back in favour

    NARCIS (Netherlands)

    Sikkema, A.; Ramakers, P.M.J.

    2010-01-01

    The Aphidius matricariae wasp of the Ichneumon family was widely used to get rid of plant lice in greenhouse agriculture up to fifteen years ago. Since then, it has given way to its American cousin, Aphidius colemani. A comparative study by the Wageningen UR Greenhouse Horticulture group has led to

  20. Study of hierarchical federation architecture using multi-resolution modeling

    Institute of Scientific and Technical Information of China (English)

    HAO Yan-ling; SHEN Dong-hui; QIAN Hua-ming; DENG Ming-hui

    2004-01-01

    This paper aims at finding a solution to the problem aroused in complex system simulation, where a specific functional federation is coupled with other simulation systems. In other words, the communication information within the system may be received by other federates that participated in this united simulation. For the purpose of ensuring simulation system unitary character, a hierarchical federation architecture (HFA) is taken. Also considering the real situation, where federates in a complicated simulation system can be made simpler to an extent, a multi-resolution modeling (MRM) method is imported to implement the design of hierarchical federation. By utilizing the multiple resolution entity (MRE) modeling approach, MRE for federates are designed out. When different level training simulation is required, the appropriate MRE at corresponding layers can be called. The design method realizes the reuse feature of the simulation system and reduces simulation complexity and improves the validity of system Simulation Cost (SC). Taking submarine voyage training simulator (SVTS) for instance, a HFA for submarine is constructed inthis paper, which approves the feasibility of studied approach.

  1. Federal Lighting Efficiency Program (FLEP). Volume 1. Study Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1977-05-06

    The study was conducted to develop a 10-year Federal Lighting Efficiency Program. It consisted of four analytical tasks: conduct a survey of recent lighting research and development;conduct a cost/benefit evaluation of energy-conserving options available as a result of the lighting research; develop a cost-effective Federal Lighting Efficiency Program plan based on the study results; and identify commercialization barriers that may exist that prevent widespread utilization of the energy-conserving options. The results are summarized in this volume. (ERA citation 04:044906)

  2. Case studies of geothermal leasing and development on federal lands

    Energy Technology Data Exchange (ETDEWEB)

    Trummel, Marc

    1978-09-29

    In response to a widely expressed need to examine the impact of the federal regulatory system on the rate of geothermal power development, the Department of Energy-Division of Geothermal Energy (DGE) has established a Streamlining Task Force in cooperation with appropriate federal agencies. The intent is to find a way of speeding development by modification of existing laws or regulations or by better understanding and mechanization of the existing ones. The initial focus was on the leasing and development of federal lands. How do the existing processes work? Would changes produce positive results in a variety of cases? These are questions which must be considered in a national streamlining process. This report presents case studies of federal leasing actions on seven diverse locations in the western region. Characteristics of existing high geothermal potential areas are quite diverse; geography, environment, industry interest and the attitudes and activities of the responsible federal land management agencies and the interested public vary widely. Included are descriptions of post and current activities in leasing exploration and development and discussions of the probable future direction of activities based on current plans. Implications of these plans are presented. The case studies were based on field interviews with the appropriate State and District BLM officer and with the regional forester's office and the particular forest office. Documentation was utilized to the extent possible and has been included in whole or in part in appendices as appropriate.

  3. Environmental adversity and uncertainty favour cooperation

    Science.gov (United States)

    Andras, Peter; Lazarus, John; Roberts, Gilbert

    2007-01-01

    Background A major cornerstone of evolutionary biology theory is the explanation of the emergence of cooperation in communities of selfish individuals. There is an unexplained tendency in the plant and animal world – with examples from alpine plants, worms, fish, mole-rats, monkeys and humans – for cooperation to flourish where the environment is more adverse (harsher) or more unpredictable. Results Using mathematical arguments and computer simulations we show that in more adverse environments individuals perceive their resources to be more unpredictable, and that this unpredictability favours cooperation. First we show analytically that in a more adverse environment the individual experiences greater perceived uncertainty. Second we show through a simulation study that more perceived uncertainty implies higher level of cooperation in communities of selfish individuals. Conclusion This study captures the essential features of the natural examples: the positive impact of resource adversity or uncertainty on cooperation. These newly discovered connections between environmental adversity, uncertainty and cooperation help to explain the emergence and evolution of cooperation in animal and human societies. PMID:18053138

  4. Environmental adversity and uncertainty favour cooperation

    Directory of Open Access Journals (Sweden)

    Lazarus John

    2007-11-01

    Full Text Available Abstract Background A major cornerstone of evolutionary biology theory is the explanation of the emergence of cooperation in communities of selfish individuals. There is an unexplained tendency in the plant and animal world – with examples from alpine plants, worms, fish, mole-rats, monkeys and humans – for cooperation to flourish where the environment is more adverse (harsher or more unpredictable. Results Using mathematical arguments and computer simulations we show that in more adverse environments individuals perceive their resources to be more unpredictable, and that this unpredictability favours cooperation. First we show analytically that in a more adverse environment the individual experiences greater perceived uncertainty. Second we show through a simulation study that more perceived uncertainty implies higher level of cooperation in communities of selfish individuals. Conclusion This study captures the essential features of the natural examples: the positive impact of resource adversity or uncertainty on cooperation. These newly discovered connections between environmental adversity, uncertainty and cooperation help to explain the emergence and evolution of cooperation in animal and human societies.

  5. Iodixanol Has a Favourable Fibrinolytic Profile Compared to Iohexol in Cardiac Patients Undergoing Elective Angiography: A Double-Blind, Randomized, Parallel Group Study.

    Directory of Open Access Journals (Sweden)

    Andrew T Treweeke

    Full Text Available There is no consensus and a limited evidence base for choice of contrast agents (CA in angiography. This study evaluated the impact of iohexol and iodixanol CA on fibrinolytic factors (tissue plasminogen activator [t-PA] and plasminogen activator inhibitor-1 [PAI-1], as well as platelet-monocyte conjugates in cardiac patients undergoing elective angiography in a double-blind, randomised parallel group study.Patients (men, 50-70 years old; n = 12 were randomised to receive either iohexol (Omnipaque; n = 6 or iodixanol (Visipaque; n = 6 during elective angiography at Raigmore Hospital, Inverness, UK. Arterial and venous blood samples were drawn prior to CA delivery and following angiography. Assessment of platelet-monocyte conjugation, t-PA and PAI-1 antigen and activity was conducted in samples pre- and post-angiography.Plasma t-PA antigen was depressed equally in the study groups after angiography, but there was a greater reduction in PAI-1 antigen in the group receiving iodixanol. These findings corresponded to a substantial reduction in t-PA activity in patients receiving iohexol, with no change in those receiving iodixanol (P = 0.023 between the CA groups. Both CAs caused a reduction in platelet-monocyte conjugation, with no difference between the groups. No adverse events were reported during the trial.Avoiding reduced plasma t-PA activity might be an important consideration in choosing iodixanol over iohexol in patients at risk of thrombosis following angiography. The trial is registered on the ISRCTN register (ISRCTN51509735 and funded by the Coronary Thrombosis Trust and National Health Service (Highland R&D Endowments. The funders had no influence over study design or reporting.Controlled-Trials.com ISRCTN51509735.

  6. On The Study Of Federal Capitals: A Review Article

    Directory of Open Access Journals (Sweden)

    Roger Wettenhall

    2010-07-01

    Full Text Available It is fitting that Canada, as one of the world's leading federations, should play host to important ventures in the study of federal capitals, and in the analysis of how these capitals are governed and financed. A generation ago it was Canadian professor of political science Donald Rowat who produced the first anthology of these capitals. His edited book, with 17 case studies contributed by leading scholars of the time, provided excellent coverage of its subject and has remained the major text in the field for over 30 years. But there have been important developments in the field since Rowat's book was published by University of Toronto Press (Rowat 1973, and we can be thankful that another Canada-based team has produced a sequel volume that brings the story up-to-date and extends it in significant ways (Slack & Chattopadhyay 2009.

  7. Evidence in Favour of IMF Variations

    OpenAIRE

    Eisenhauer, Frank

    2001-01-01

    The stellar initial mass function (IMF) determines the relative number of stars born at a given mass. Despite the tremendous effort to establish a universal IMF, the astronomical literature offers a wealth of diverse evidence for IMF variations. This review was prepared for a controversial debate at the conference ``Starbursts -- Near and Far'' at Ringberg Castle, 2000, and gives a one-sided portrayal in favour of IMF variations. I will summarise the empirical evidence that the IMF varies wit...

  8. Patterns of federal Internet offenders: a pilot study.

    Science.gov (United States)

    Burgess, Ann W; Carretta, Carrie M; Burgess, Allen G

    2012-09-01

    Internet-facilitated sexual offending is receiving increased forensic and clinical attention. Two issues confront this field. First, studies are equivocal as to whether (or not) the possession of Internet pornography can escalate to contact sexual offenses against a child, and second, federal judges have been questioning the length of sentences for users only of child pornography. The findings of this pilot study of 101 federal Internet offenders revealed over half of the men at the time of arrest were employed, educated, were in (or had been in) a relationship, had children, and did not have a prior criminal offense, suggesting a changing profile of a convicted sex offender. Forensic and psychiatric nurses who evaluate users of child pornography contraband need to be knowledgeable of Internet file transfer technology and the various types of contraband viewed specifically for the age of the preferred child, extreme acts to the child (e.g., bondage, S&M), and whether the user prefers images of adults with children or images of children only.

  9. Observational evidence favours a static universe

    CERN Document Server

    Crawford, David F

    2010-01-01

    The common attribute of all Big Bang cosmologies is that they are based on the assumption that the universe is expanding. However examination of the evidence for this expansion clearly favours a static universe. The major topics considered are: Tolman surface brightness, angular size, type 1a supernovae, gamma ray bursts, galaxy distributions, quasar distributions, X-ray background radiation, cosmic microwave background radiation, radio source counts, quasar variability and the Butcher--Oemler effect. An analysis of the best raw data for these topics shows that they are consistent with expansion only if there is evolution that cancels the effects of expansion. An alternate cosmology, curvature cosmology, is in full agreement with the raw data. This tired-light cosmology predicts a well defined static and stable universe and is fully described. It not only predicts accurate values for the Hubble constant and the temperature of cosmic microwave background radiation but shows excellent agreement with most of the...

  10. Determinants of favourable opinions about euthanasia in a sample of French physicians

    National Research Council Canada - National Science Library

    Dany, Lionel; Baumstarck, Karine; Dudoit, Eric; Duffaud, Florence; Auquier, Pascal; Salas, Sébastien

    2015-01-01

    .... The objective of this study in a sample of French physicians was to establish the potential determinants of a favourable opinion about euthanasia in general and when faced with a specific situation...

  11. Preliminary Study of Favourable Formations for CO{sub 2} Subsurface Storage in Spain; Estudio Preliminar de las Formaciones Favorables para el Almacenamiento Subterraneo de CO{sub 2} en Espana

    Energy Technology Data Exchange (ETDEWEB)

    Zapatero, M. A.; Reyes, J. L.; Martinez, R.; Suarez, I.; Arenillas, A.; Perucha, M. A.

    2009-10-12

    This report is a synthesis of the possibilities of CO{sub 2} storage in the Spanish subsurface. Compilation and analysis of geological information has been carried out, looking at surface and subsurface, in order to make a pre-selection of potential favourable units for CO{sub 2} storage, taking in account that each of this storages needs a confining formation to seal the storage. Before the storage selection, a general description of the great geological units of the Iberian Peninsula is done. Afterwards, borehole logging from petroleum exploration is analysed in these units, formations and areas of interest. The aim is to finally obtain a description of selected units and their possibilities of CO{sub 2} storage. (Author) 17 refs.

  12. Should Marketers Try to Change Consumers Unfavourable Attitude for their Product into Favourable?

    OpenAIRE

    Sunday O. E. Ewah; Patrick M. Igbaji; Christian I. Umeh

    2014-01-01

    This is an empirical study of the interplay between consumers' attitude toward marketers’ products and marketers; wish to elicit favourable buying behaviour from the consumer. According to the study the process of this transformation of consumer’s attitude is not quite easy. The marketers have to put their acts together by producing products to match consumers attitude or build a gradual change that will result to favourable buying decision from the consumer.

  13. Analyzing Social Issues Related to Teaching about the Federal Budget, Federal Debt, and Budget Deficit in Fifty State High School Social Studies Standards

    Science.gov (United States)

    Marri, Anand R.; Crocco, Margaret S.; Shuttleworth, Jay; Gaudelli, William; Grolnick, Maureen

    2012-01-01

    This study of all fifty state, high school social studies curriculum standards found a lack of attention in the vast majority of state standards to the federal budget, federal debt, and budget deficit, topics of significant concern. These concepts are important to teaching about economics in the United States since they lie at the center of…

  14. Global warming favours light-coloured insects in Europe.

    Science.gov (United States)

    Zeuss, Dirk; Brandl, Roland; Brändle, Martin; Rahbek, Carsten; Brunzel, Stefan

    2014-05-27

    Associations between biological traits of animals and climate are well documented by physiological and local-scale studies. However, whether an ecophysiological phenomenon can affect large-scale biogeographical patterns of insects is largely unknown. Insects absorb energy from the sun to become mobile, and their colouration varies depending on the prevailing climate where they live. Here we show, using data of 473 European butterfly and dragonfly species, that dark-coloured insect species are favoured in cooler climates and light-coloured species in warmer climates. By comparing distribution maps of dragonflies from 1988 and 2006, we provide support for a mechanistic link between climate, functional traits and species that affects geographical distributions even at continental scales. Our results constitute a foundation for better forecasting the effect of climate change on many insect groups.

  15. Reported Experiences Enhance Favourable Attitudes toward Toads

    Science.gov (United States)

    Tomazic, Iztok

    2011-01-01

    There are many factors that influence the formation of attitudes, one of the most crucial ones being education. Positive attitudes toward animals can be effectively accomplished principally by enabling students to directly experience organisms and their environments. The following study presents the development of a Toad Attitude Questionnaire…

  16. Natural selection can favour 'irrational' behaviour

    OpenAIRE

    McNamara, J. M.; Trimmer, P. C.; Houston, A. I.

    2014-01-01

    Understanding decisions is the fundamental aim of the behavioural sciences. The theory of rational choice is based on axiomatic principles such as transitivity and independence of irrelevant alternatives (IIA). Empirical studies have demonstrated that the behaviour of humans and other animals often seems irrational; there can be a lack of transitivity in choice and seemingly irrelevant alternatives can alter decisions. These violations of transitivity and IIA undermine rational choice theory....

  17. Understanding the data-action cycle of surveillance: a qualitative study of federal and state stakeholders.

    Science.gov (United States)

    Lindsay, Ana Cristina; Sussner, Katarina M; Greaney, Mary L; Mierzwa, Sharon; Rich-Edwards, Janet; Wiecha, Jean; Peterson, Karen

    2010-03-01

    This qualitative study aims to understand how personnel in state and federal agencies view surveillance systems and the extent to which systematically collected data inform nutrition and physical activity policies and interventions addressing obesity. In-depth interviews were conducted with 17 respondents purposively sampled from state health departments, federal public health agencies, and prevention research centers. All informants acknowledged the importance of surveillance systems and influence of the data-action cycle for monitoring trends and increasing obesity awareness. However, state-level respondents believed surveillance systems should be designed for programmatic purposes, whereas federal participants thought they should be designed for monitoring. Respondents held differing opinions about the flexibility, timeliness, accessibility, and usefulness of existing national surveillance systems, highlighting significant differences in state and federal agencies' perceptions and utilization of surveillance systems. Such discrepancies call for increased communication surrounding purposes and uses of surveillance data, enabling stronger partnerships between state and federal agencies.

  18. Natural selection can favour 'irrational' behaviour.

    Science.gov (United States)

    McNamara, J M; Trimmer, P C; Houston, A I

    2014-01-01

    Understanding decisions is the fundamental aim of the behavioural sciences. The theory of rational choice is based on axiomatic principles such as transitivity and independence of irrelevant alternatives (IIA). Empirical studies have demonstrated that the behaviour of humans and other animals often seems irrational; there can be a lack of transitivity in choice and seemingly irrelevant alternatives can alter decisions. These violations of transitivity and IIA undermine rational choice theory. However, we show that an individual that is maximizing its rate of food gain can exhibit failure of transitivity and IIA. We show that such violations can be caused because a current option may disappear in the near future or a better option may reappear soon. Current food options can be indicative of food availability in the near future, and this key feature can result in apparently irrational behaviour.

  19. Searching development strategies for less-favoured areas

    NARCIS (Netherlands)

    Ruben, R.; Kuiper, M.H.; Pender, J.

    2006-01-01

    Rural households in less-favoured areas (LFAs) face multiple constraints for overcoming chronic poverty and resource degradation. Strategic development options can be assessed through interdisciplinary research based on coupling of human and natural systems approaches. Simulation modelling enables t

  20. Management of information security risks in a federal public institution: a case study

    OpenAIRE

    Jackson Gomes Soares Souza; Carlos Hideo Arima; Renata Maria Nogueira de Oliveira; Getulio Akabane; Napoleão Verardi Galegale

    2016-01-01

    Public institutions bound to the Brazilian federal public sector must apply security measures, policies, procedures and guidelines as information assets protection measures. This case study sought to determine whether the management of information security risks is applied in a federal public institution according to Information Technology (I.T.) managers perceptions and the results expose the importance of the roles played by people, responsibilities, policies, standards, procedures and thei...

  1. Federated Search and the Library Web Site: A Study of Association of Research Libraries Member Web Sites

    Science.gov (United States)

    Williams, Sarah C.

    2010-01-01

    The purpose of this study was to investigate how federated search engines are incorporated into the Web sites of libraries in the Association of Research Libraries. In 2009, information was gathered for each library in the Association of Research Libraries with a federated search engine. This included the name of the federated search service and…

  2. IT Investment Allocation and Organizational Performance: A Study of Information Technology Investment Portfolios in Federal Government Agencies

    Science.gov (United States)

    Whitehead, Ennis Jim C., III

    2011-01-01

    This study examined Federal Government Information Technology (IT) portfolio investments for twenty-seven Federal Government agencies, as provided annually to the Office of Management and Budget (OMB) in their Agency IT Investment Portfolio Reports (Exhibit 53), and divided Federal agency IT investments into four categories: Innovation,…

  3. Federated Search and the Library Web Site: A Study of Association of Research Libraries Member Web Sites

    Science.gov (United States)

    Williams, Sarah C.

    2010-01-01

    The purpose of this study was to investigate how federated search engines are incorporated into the Web sites of libraries in the Association of Research Libraries. In 2009, information was gathered for each library in the Association of Research Libraries with a federated search engine. This included the name of the federated search service and…

  4. The Effects of the Federal Work-Study Program on Student Persistence and Accrued Loan Debt

    Science.gov (United States)

    Carter, Ronatta Daphne

    2012-01-01

    This study examined the impact of participation and non-participation in a federal work-study (FWS) program on student persistence and accrued student debt for undergraduate students enrolled in a small, public, four-year, liberal arts college in the South. Sanford's (1967) theory of Challenge and Support and Tinto's (1986) Integration Model were…

  5. The Causal Effect of Federal Work-Study Participation: Quasi-Experimental Evidence from West Virginia

    Science.gov (United States)

    Scott-Clayton, Judith

    2011-01-01

    Since 1964, the Federal Work-Study (FWS) program has provided funds to subsidize the wages of student employees, but it has never been studied directly. I use an instrumental variables difference-in-difference framework with administrative data from West Virginia to identify causal effects, comparing eligible and ineligible students across…

  6. The Federal Work-Study Program: Impacts on Academic Outcomes and Employment. CAPSEE Policy Brief

    Science.gov (United States)

    Center for Analysis of Postsecondary Education and Employment, 2015

    2015-01-01

    Policymakers may be interested in the extent to which Federal Work-Study programs (FWS) increase students' access to productive employment, and how they impact students' academic and career success. This brief summarizes findings from a recent study using national data and a propensity score matching approach to examine the overall effects of FWS…

  7. The veil of ignorance can favour biological cooperation.

    Science.gov (United States)

    Queller, David C; Strassmann, Joan E

    2013-01-01

    Lack of information is a constraint but ignorance can sometimes assist the evolution of cooperation by constraining selfishness. We discuss examples involving both ignorance of role or pay-off and ignorance of relatedness. Ignorance can favour cooperative traits like grouping and warning coloration and reduce conflicts from meiotic drive, imprinting, greenbeards and various forms of nepotism.

  8. Management of information security risks in a federal public institution: a case study

    Directory of Open Access Journals (Sweden)

    Jackson Gomes Soares Souza

    2016-11-01

    Full Text Available Public institutions bound to the Brazilian federal public sector must apply security measures, policies, procedures and guidelines as information assets protection measures. This case study sought to determine whether the management of information security risks is applied in a federal public institution according to Information Technology (I.T. managers perceptions and the results expose the importance of the roles played by people, responsibilities, policies, standards, procedures and their implementation aiming greater control of information security risks and opportunities related to information technology security.

  9. The Micropolitics of Distributed Leadership: Four Case Studies of School Federations

    Science.gov (United States)

    Piot, Liesbeth; Kelchtermans, Geert

    2016-01-01

    This study analyses the collaboration between principals within four Flemish school federations (voluntary collaborative networks between either primary or secondary schools). Interview data from principals were analysed using a micropolitical perspective. A central idea in micropolitical theory is that organization members' actions (and…

  10. The Federal Work-Study Program: Impacts on Academic Outcomes and Employment. Policy Brief

    Science.gov (United States)

    Center for Analysis of Postsecondary Education and Employment, 2015

    2015-01-01

    Student employment subsidies are one of the largest types of employment subsidies and one of the oldest forms of student aid. The Federal Work-Study program (FWS) is the largest student employment subsidy program; since 1964, it has provided about $1 billion per year to cover 75 percent of wages for student employees, who typically work on campus…

  11. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Schey, Stephen [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Francfort, Jim [Idaho National Laboratory (INL), Idaho Falls, ID (United States)

    2015-06-01

    Collect and evaluate data on federal fleet operations as part of the Advanced Vehicle Testing Activity’s Federal Fleet Vehicle Data Logging and Characterization Study. The Advanced Vehicle Testing Activity study seeks to collect and evaluate data to validate the utilization of advanced plug-in electric vehicle (PEV) transportation. This report summarizes the fleets studied to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of PEVs into the agencies’ fleets. Individual observations of these selected vehicles provide the basis for recommendations related to electric vehicle adoption and whether a battery electric vehicle or plug-in hybrid electric vehicle (collectively referred to as PEVs) can fulfill the mission requirements.

  12. Impact of Security Awareness Programs on End-User Security Behavior: A Quantitative Study of Federal Workers

    Science.gov (United States)

    Smith, Gwendolynn T.

    2012-01-01

    The increasing dependence on technology presented more vulnerability to security breaches of information and the need to assess security awareness levels in federal organizations, as well as other organizations. Increased headlines of security breaches of federal employees' security actions prompted this study. The research study reviewed the…

  13. Using linked federal and state data to study the adequacy of workers' compensation benefits.

    Science.gov (United States)

    Seabury, Seth A; Scherer, Ethan; O'Leary, Paul; Ozonoff, Al; Boden, Leslie

    2014-10-01

    We combined federal and state administrative data to study the long-term earnings losses associated with occupational injuries and assess the adequacy of workers' compensation benefits. We linked state data on workers' compensation claims from New Mexico for claimants injured from 1994 to 2000 to federal earnings records from 1987 to 2007. We estimated earnings losses up to 10 years after injury and computed the fraction of losses replaced by benefits. Workers with lost-time injuries lost an average of 15% of their earnings over the 10 years after injury. On average, workers' compensation income benefits replaced 16% of these losses. Men and women had similar losses and replacement rates. Workers with minor injuries had lower losses but also had lower replacement rates. Earnings losses after an injury are highly persistent, even for comparatively minor injuries. Income benefits replace a smaller fraction of those losses than previously believed. © 2014 Wiley Periodicals, Inc.

  14. Arguments in favour of compulsory treatment of opioid dependence.

    Science.gov (United States)

    Wu, Zunyou

    2013-02-01

    Twelve agencies of the United Nations, including the World Health Organization, have issued a joint statement that calls on Member States to replace the compulsory detention of people who use opioids in treatment centres with voluntary, evidence-informed and rights-based health and social services. The arguments in favour of this position fall into three broad categories: Compulsory treatment centres infringe on an individual's liberty, they put human beings at risk of harm, and evidence of their effectiveness against opioid dependence has not been generated. The United Nations statement underscores that although countries apply different criteria for sending individuals to compulsory treatment centres, detention often takes place without due process, legal safeguards or judicial review. This clearly violates internationally recognized human rights standards. Furthermore, people who are committed to these centres are often exposed to physical and sexual violence, forced labour and sub-standard living conditions. They are often denied health care, despite their heightened vulnerability to HIV infection and tuberculosis. Finally, there is no evidence, according to the statement, that these centres offer an environment that is conducive to recovery from opioid dependence or to the rehabilitation of commercial sex workers or of children who have suffered sexual exploitation, abuse or lack of care and protection. The author of this paper sets forth several arguments that counter the position taken by the United Nations and argues in favour of compulsory treatment within a broader harm reduction strategy aimed at protecting society as well as the individual concerned.

  15. Cryptic female choice via sperm dumping favours male copulatory courtship in a spider.

    Science.gov (United States)

    Peretti, A V; Eberhard, W G

    2010-02-01

    Males of many animals perform 'copulatory courtship' during copulation, but the possible reproductive significance of this behaviour has seldom been investigated. In some animals, including the spider Physocyclus globosus (Pholcidae), the female discards sperm during or immediately following some copulations. In this study, we determined which of several variables associated with copulation correlated with paternity success in P. globosus when two males mate with a single female. Then, by determining which of these variables also correlated with sperm dumping, we inferred which variables may affect paternity via the mechanism of sperm dumping. Male abdomen vibration (a copulatory courtship behaviour) and male genitalic squeezing both correlated with both paternity and sperm dumping; so, these traits may be favoured by biased sperm dumping. Biased sperm dumping may also be the mechanism by which possible cryptic female choice favours another male trait that was the subject of a previous study, responsiveness to female stridulation.

  16. Approaches and Technologies for Systems Integration: A Case Study at the Federal University of Lavras

    Directory of Open Access Journals (Sweden)

    GARCIA, C. M.

    2015-06-01

    Full Text Available This case study aims to analyze the integration's approaches and technologies among information systems and services in an academic environment. It has been done a study on the integration history in the Federal University of Lavras. The data had been gathered via questionnaires and documentation analysis. In this analysis, 4 distinct phases were specified. Besides, the advantages and disadvantages of each phase were discussed. The main contribution of this work is the analysis of different integration approaches among information systems and other services.

  17. Federal Holidays

    Data.gov (United States)

    Office of Personnel Management — Federal law (5 U.S.C. 6103) establishes the following public holidays for Federal employees. Please note that most Federal employees work on a Monday through Friday...

  18. Employee participation in the private sector in Malaysia: The Applicability of Favourable Conjunctures Model

    Directory of Open Access Journals (Sweden)

    Balakrishnan Parasuraman

    2009-12-01

    Full Text Available EP is one crucial aspect of the employment relationship in both private and public organisations in many countries. In 2001, Poole, Lansbury and Wiles developed a model for comparative EP, which they named the Favourable Conjunctures Model. So far, this model has only been applied in developed countries such as the United States of America, United Kingdom, Australia and Europe. There it was applied in order to examine worker participation from the national perspective. No extensive study has been conducted using this model to explain worker participation practices at the company level. In parallel with this aspect, this model also has never been used to explain the nature of EP in the Asian developing countries. This current research will use the Favourable Conjunctures Model to examine the nature of EP in private enterprises based on empirical study carried out in Malaysia. The argument of this paper is that the Favourable Conjunctures Model of Industrial Democracy (Poole et al. 2001 is inadequate to elucidate the characteristics of EP in Malaysia. Based on empirical findings from three private companies in Malaysia, the paper argues that there are many contextual factors that influence the nature of EP in Malaysian private companies that are not taken into account by the model. They are:multi-ethnic (cultural influences, the repressive role of state in the Malaysian industrial relations, the New Economic Policy and industrialisation plan, Islamic working ethics, the influence of a British colonial history, lack of training among non-managerial employees in EP, the impact of foreign direct investment on industrial relations, to identify a few. Based on this study, it is proposed that the present Favourable Conjunctures Model of Industrial Democracy (Poole et al. 2001 be modified based on the contextual factors discussed above. The paper concludes that the western model of EP could not be directly applied in Malaysia without some adjustment of

  19. Determinants of favourable opinions about euthanasia in a sample of French physicians.

    Science.gov (United States)

    Dany, Lionel; Baumstarck, Karine; Dudoit, Eric; Duffaud, Florence; Auquier, Pascal; Salas, Sébastien

    2015-11-05

    The question whether euthanasia should be legalised has led to substantial public debate in France. The objective of this study in a sample of French physicians was to establish the potential determinants of a favourable opinion about euthanasia in general and when faced with a specific situation as embodied in the Humbert affair. The study was a cross-sectional survey investigating two different samples of medical doctors: (1) those specialised in palliative care and affiliated to the French Society for Patient Accompaniment and Palliative Care; (2) medical interns (medical doctors in training course) in a French medical university (Marseille). A questionnaire was sent (email) to each voluntary participant including sociodemographics, professional status, mention of believing in God, and opinion about euthanasia (the question was designed to assess the general opinion about euthanasia and the opinion about a specific case, the Vincent Humbert' case (a man who was rendered quadriplegic, blind, and mute after an accident and has requested euthanasia). A total of 413 physicians participated in the research (participation rate: 48.5%). Less than half of the population were favourable to euthanasia in general and almost two-thirds of the population were favourable to Vincent Humbert's request for euthanasia. Based on the multivariate analysis, individuals believing in God and being a medical intern were significant independent factors linked to having a favourable opinion about euthanasia in general and about the Vincent Humbert's request. There is still no study in France on the development of opinion about euthanasia and its impact. The issue goes beyond the strictly professional sphere and involves broader socio-political stakes. These stakes do not necessarily take into account medical practices and experiences or the desires of end-of-life patients. The professional upheaval that the future French legal framework will doubtlessly trigger will require further

  20. Will Hydrogen be Competitive in Europe without Tax-Favours?

    DEFF Research Database (Denmark)

    Hansen, Anders Chr.

    2010-01-01

    Hydrogen is one of the alternative transport fuels expected to replace conventional oil based fuels. The paper finds that it is possible for non-fossil-based hydrogen to become the lowest cost fuel without favourable tax treatment. The order of per kilometre cost depends on performance in hydrogen...... production, the international oil price, and fuel taxes. At low oil prices, the highest per kilometre costs were found for non-fossil power-based hydrogen, the second highest for natural gas-based hydrogen, and the lowest for conventional fuels. At high oil prices, this ranking is reversed and non......-fossil power-based hydrogen becomes the most cost competitive fuel. General fuel taxes lower the threshold at which the international oil price reverses this competitiveness order. The highest fuel tax rates applied in Europe lowers this threshold oil price considerably, whereas the lowest fuel taxes may...

  1. Physiological adaptations to weight loss and factors favouring weight regain.

    Science.gov (United States)

    Greenway, F L

    2015-08-01

    Obesity is a major global health problem and predisposes individuals to several comorbidities that can affect life expectancy. Interventions based on lifestyle modification (for example, improved diet and exercise) are integral components in the management of obesity. However, although weight loss can be achieved through dietary restriction and/or increased physical activity, over the long term many individuals regain weight. The aim of this article is to review the research into the processes and mechanisms that underpin weight regain after weight loss and comment on future strategies to address them. Maintenance of body weight is regulated by the interaction of a number of processes, encompassing homoeostatic, environmental and behavioural factors. In homoeostatic regulation, the hypothalamus has a central role in integrating signals regarding food intake, energy balance and body weight, while an 'obesogenic' environment and behavioural patterns exert effects on the amount and type of food intake and physical activity. The roles of other environmental factors are also now being considered, including sleep debt and iatrogenic effects of medications, many of which warrant further investigation. Unfortunately, physiological adaptations to weight loss favour weight regain. These changes include perturbations in the levels of circulating appetite-related hormones and energy homoeostasis, in addition to alterations in nutrient metabolism and subjective appetite. To maintain weight loss, individuals must adhere to behaviours that counteract physiological adaptations and other factors favouring weight regain. It is difficult to overcome physiology with behaviour. Weight loss medications and surgery change the physiology of body weight regulation and are the best chance for long-term success. An increased understanding of the physiology of weight loss and regain will underpin the development of future strategies to support overweight and obese individuals in their efforts

  2. Statistics and Probability at Secondary Schools in the Federal State of Salzburg: An Empirical Study

    Directory of Open Access Journals (Sweden)

    Wolfgang Voit

    2014-12-01

    Full Text Available Knowledge about the practical use of statistics and probability in today's mathematics instruction at secondary schools is vital in order to improve the academic education for future teachers. We have conducted an empirical study among school teachers to inform towards improved mathematics instruction and teacher preparation. The study provides a snapshot into the daily practice of instruction at school. Centered around the four following questions, the status of statistics and probability was examined. Where did  the current mathematics teachers study? What relevance do statistics and probability have in school? Which contents are actually taught in class? What kind of continuing education would be desirable for teachers? The study population consisted of all teachers of mathematics at secondary schools in the federal state of Salzburg.

  3. Partner switching can favour cooperation in a biological market.

    Science.gov (United States)

    Schwagmeyer, P L

    2014-09-01

    Intraspecific cooperation and interspecific mutualisms can be promoted by mechanisms that reduce the frequency with which cooperative organisms are exploited by unhelpful partners. One such mechanism consists of changing partners after interacting with an uncooperative individual. I used McNamara et al.'s (Nature, 451, 2008, 189) partner switching model as a framework to examine whether this mechanism can select for increased cooperative investment by house sparrows (Passer domesticus) collaborating to rear offspring; previous research on this species has shown that substantial cooperative investments by both pair members are required to achieve high pay-offs from collaborating. I found that the poorer the outcome of a breeding attempt relative to the number of eggs the female invested, the greater the likelihood of partner switching. The incidence of partner switching changed seasonally, with peak switching coinciding with an increase in the number of alternative partners available to females. After females switched partners, their breeding outcomes rose to match those of females that remained with the same partner; this was not the case for males that switched partners. Consistent with the model's prediction, males in stable partnerships achieved over 25% higher than average reproductive success, which was attributable to both persistently good breeding outcomes and their older partners' high fecundity. These results provide empirical support for the hypothesis that partner switching favours increased cooperative investment levels, and they demonstrate that variation in the relative value of by-product benefits can enhance that process.

  4. Evolution of trust and trustworthiness: social awareness favours personality differences.

    Science.gov (United States)

    McNamara, John M; Stephens, Philip A; Dall, Sasha R X; Houston, Alasdair I

    2009-02-22

    Interest in the evolution and maintenance of personality is burgeoning. Individuals of diverse animal species differ in their aggressiveness, fearfulness, sociability and activity. Strong trade-offs, mutation-selection balance, spatio-temporal fluctuations in selection, frequency dependence and good-genes mate choice are invoked to explain heritable personality variation, yet for continuous behavioural traits, it remains unclear which selective force is likely to maintain distinct polymorphisms. Using a model of trust and cooperation, we show how allowing individuals to monitor each other's cooperative tendencies, at a cost, can select for heritable polymorphisms in trustworthiness. This variation, in turn, favours costly 'social awareness' in some individuals. Feedback of this sort can explain the individual differences in trust and trustworthiness so often documented by economists in experimental public goods games across a range of cultures. Our work adds to growing evidence that evolutionary game theorists can no longer afford to ignore the importance of real world inter-individual variation in their models.

  5. 77 FR 31600 - Federal Need Analysis Methodology for the 2013-2014 Award Year: Federal Pell Grant, Federal...

    Science.gov (United States)

    2012-05-29

    ..., Federal Work-Study, Federal Supplemental Educational Opportunity Grant, William D. Ford Federal Direct... Supplemental Educational Opportunity Grant Program; 84.268 William D. Ford Federal Direct Loan Program; 84.379..., Federal Perkins Loan, Federal Work-Study, Federal Supplemental Educational Opportunity Grant, William...

  6. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for NASA Stennis Space Center

    Energy Technology Data Exchange (ETDEWEB)

    Schey, Stephen [Idaho National Lab. (INL), Idaho Falls, ID (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    Federal agencies are mandated to purchase alternative fuel vehicles, increase consumption of alternative fuels, and reduce petroleum consumption. Available plug-in electric vehicles (PEVs) provide an attractive option in the selection of alternative fuel vehicles. PEVs, which consist of both battery electric vehicles (BEVs) and plug-in hybrid electric vehicles (PHEVs), have significant advantages over internal combustion engine (ICE) vehicles in terms of energy efficiency, reduced petroleum consumption, and reduced production of greenhouse gas (GHG) emissions, and they provide performance benefits with quieter, smoother operation. This study intended to evaluate the extent to which NASA Stennis Space Center (Stennis) could convert part or all of their fleet of vehicles from petroleum-fueled vehicles to PEVs.

  7. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for United States Coast Guard Headquarters

    Energy Technology Data Exchange (ETDEWEB)

    Schey, Stephen [Idaho National Lab. (INL), Idaho Falls, ID (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    Federal agencies are mandated to purchase alternative fuel vehicles, increase consumption of alternative fuels, and reduce petroleum consumption. Available plug-in electric vehicles (PEVs) provide an attractive option in the selection of alternative fuel vehicles. PEVs, which consist of both battery electric vehicles (BEVs) and plug-in hybrid electric vehicles (PHEVs), have significant advantages over internal combustion engine (ICE) vehicles in terms of energy efficiency, reduced petroleum consumption, and reduced production of greenhouse gas (GHG) emissions, and they provide performance benefits with quieter, smoother operation. This study intended to evaluate the extent to which the United States Coast Guard Headquarters (USCG HQ) could convert part or all of their fleet of vehicles from petroleum-fueled vehicles to PEVs.

  8. Federalism Lives.

    Science.gov (United States)

    Howard, A. E. Dick

    1987-01-01

    Examines the concept of federalism in terms of its past history and its encouraging future. Calls for a revival of concern for federalism not simply as a convenient administrative arrangement but as a fundamental constitutional value. (BSR)

  9. The Favourable Health Behaviours in Women from a Selected Urban Region in Kayseri

    Directory of Open Access Journals (Sweden)

    Hacer Sonmezer,Fevziye Cetinkaya,Melis Nacar

    2012-10-01

    Full Text Available Objective: In this study it was aimed to establish the favourable health behaviours in the life style of women, who also are in charge, and carry the responsibility of the whole family’s health. Material and Method: A questionnaire, inquiring about some favourable health behaviours, was applied to 421 women aged 18-64, living in an urban region in Kayseri. Results: The mean age of the study group was 36.2±11.1, 57.1% were housewives, 74.3% were married, and the educational level of 62.7% was high school and above. The rate of obtaining information from health personnel was 9.7%, and most women(31.1% stated media as their source of information. 67.0% did not smoke. 44.4% of the study group were with in normal weight, and 66.3% stated that they had breakfast. 32.3% of the women stated that they restricted salt in food, and 18.8% restricted sugar, 20.4% tried not to consume tea following a meal and 32.1% stated that they were always careful about not using saturated fat while cooking. 16.2% of the women stated that they self-examined their breats on a regular basis, 54.0% that they did so sometimes, 41.6% had had a clinical breast examination. The rate of mammograhpic evaluation above the age of 40 was 78.0%. Conclusion: The awareness about and the applications for favourable health behaviours as a life style were found to be insufficient in women. It is the duty and responsibility of health personnel to establish healthy life style behaviours in women. [TAF Prev Med Bull 2012; 11(5.000: 521-528

  10. Behaviour patterns preceding a railway suicide: explorative study of German Federal Police officers' experiences.

    Science.gov (United States)

    Lukaschek, Karoline; Baumert, Jens; Ladwig, Karl-Heinz

    2011-08-04

    Constant high-level numbers of railway suicides indicate that prevention strategies against railway suicides are urgently needed. The main question of the present study was whether pre-crash railway suicide behaviour can be identified, using German Federal Police officers experience with suicidal events in railway related environments. To collect information on pre-crash railway suicide behaviour, a questionnaire was used and made available on the German Federal Police intranet. A total of 202 subjects (mean age: 41 years, sex: 84.9% male) were included in the analysis. Multivariate logistic regression analyses were performed to predict the prevention of suicide (first model) or demand for counselling (second model) as outcomes. Sex, age, years of service, number of experienced suicides, suicides personally observed, information on suicides obtained from witnesses and finally either counselling/debriefing (first model) or whether officers had prevented a suicide (second model) were used as predictors. A considerable proportion of police officers reported behavioural patterns preceding a suicide. Half of them observed the dropping or leaving behind of personal belongings or the avoidance of eye contact, more than a third erratic gesture, mimic or movement. Erratic communication patterns and general confusion were each reported by about one quarter. One fifth indicated the influence of alcohol. Less frequently observed behaviour was aimlessly wandering (14.3%) and out of the ordinary clothing (4%). About one third of all railway suicide victims committed suicide in stations. Of those, 70% had chosen an eminent spot. The multivariate logistic regression model using prevented suicides as the outcome identified the number of suicides experienced, counselling/debriefing and having personally observed a suicide as variables with significant impact. The model using counselling/debriefing as the outcome identified age and having prevented a suicide as variables with a

  11. Evaluation of the Favourable Ecological Impact of the Railway on the Environment

    Directory of Open Access Journals (Sweden)

    Jasna Golubić

    2012-10-01

    Full Text Available The railway has advantages over other branches of longdistancetransportation from the ecological, economic, safety,and technological point of view.The paper gives an evaluation of the favourable influenceof railway traffic on the environment reflected in the rationalenergy consumption, significantly reduced need of physicalspace, and reduced air pollution.Having these data in mind, the railway is considered tohave a negligible influence on environmental pollution. However,studying even such small amounts plays a significant rolein the traffic safety and in the lives of people and nature itself

  12. Private sector participation in Federal energy RD and D planning. [Study by National Research Council

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    The present study was started early in 1977 in response to a need expressed by the then Assistant Administrator for ERDA Planning, Analysis, and Evaluation and was endorsed by the Administrator of ERDA. The primary purpose is to explore various institutional alternatives that might be employed by the Federal government and the private sector to provide an effective coupling between the requirements of the private sector for new energy technologies and the government's planning process to develop these technologies. This also included an analysis of several institutional initiatives that have been tested by ERDA to create an effective working relationship with industry. Based on these studies, the Committee was requested to make recommendations on an appropriate institutional mechanism to improve the planning process. Chapters are entitled: The Government Role in Energy RD and D; The ERDA (DOE) Private Sector RD and D Planning Interface; Industry Perceptions of the ERDA/Private Sector Interface; Legal Constraints to DOE/Private Sector Cooperation; Instability as a Constraint to DOE/Private Sector Cooperation; and the RD and D Planning Process. An analysis of five legal problems in structuring private sector participation in joint RD and D planning is discussed in an appendix.

  13. The School as a Democratic Institution: The Problems of Teaching Social Studies in the Federal Republic of Germany.

    Science.gov (United States)

    Forsback, Marlene

    1974-01-01

    In recent years, political and social studies have been under revision in the individual states of the Federal Republic of Germany. Many states have issued framework guidelines for the various school branches and levels to provide teachers with orientation aids. Progressive educators see the goal of political and social studies as being more than…

  14. Behaviour patterns preceding a railway suicide: Explorative study of German Federal Police officers' experiences

    Directory of Open Access Journals (Sweden)

    Ladwig Karl-Heinz

    2011-08-01

    Full Text Available Abstract Background Constant high-level numbers of railway suicides indicate that prevention strategies against railway suicides are urgently needed. The main question of the present study was whether pre-crash railway suicide behaviour can be identified, using German Federal Police officers experience with suicidal events in railway related environments. Methods To collect information on pre-crash railway suicide behaviour, a questionnaire was used and made available on the German Federal Police intranet. A total of 202 subjects (mean age: 41 years, sex: 84.9% male were included in the analysis. Multivariate logistic regression analyses were performed to predict the prevention of suicide (first model or demand for counselling (second model as outcomes. Sex, age, years of service, number of experienced suicides, suicides personally observed, information on suicides obtained from witnesses and finally either counselling/debriefing (first model or whether officers had prevented a suicide (second model were used as predictors. Results A considerable proportion of police officers reported behavioural patterns preceding a suicide. Half of them observed the dropping or leaving behind of personal belongings or the avoidance of eye contact, more than a third erratic gesture, mimic or movement. Erratic communication patterns and general confusion were each reported by about one quarter. One fifth indicated the influence of alcohol. Less frequently observed behaviour was aimlessly wandering (14.3% and out of the ordinary clothing (4%. About one third of all railway suicide victims committed suicide in stations. Of those, 70% had chosen an eminent spot. The multivariate logistic regression model using prevented suicides as the outcome identified the number of suicides experienced, counselling/debriefing and having personally observed a suicide as variables with significant impact. The model using counselling/debriefing as the outcome identified age and

  15. Workplace moral harassment and its consequences: A case study in a federal higher education institution

    Directory of Open Access Journals (Sweden)

    Carmelita Angélica Guimarães

    2016-06-01

    Full Text Available ABSTRACT This paper aims to characterize a case of moral harassment in a federal institution of higher education and to identify its consequences for the different actors. We carried out a descriptive and qualitative case study and collected data by means of documentary research with an analysis of the related administrative process, which includes statements of those involved in the case, and an in-depth interview with the harassed employee. The results revealed the occurrence of vertical descendant moral harassment characterized by abuse of power, authoritarianism and perverse manipulation, with severe consequences for the harassed employee´s physical, mental and emotional health. We found that the institution's human resources management department's non-action in terms of intermediating the conflict and the institutional culture and structure may all have favored the occurrence of the case and the harasser´s impunity. For the organization, the occurrences generated degradation in the workplace and in motivation and the team split, as well as income decline and other financial losses. Beyond the financial issues, there was also even more serious damage to the society, as a public institution should look after citizens´ properties and civil rights, whether concerning finances, productivity or social areas. We can conclude that moral harassment is a multidimensional process that violates the individual´s fundamental rights with severe impact on his/her physical and psychological health, on organizations and on the society in general.

  16. A pilot study for the primary prevention of rheumatic fever in Kosrae, Federated States of Micronesia.

    Science.gov (United States)

    Kohler, L A; Alik, T; Kaplan, E L; Anderson, F L

    2010-04-01

    Rheumatic fever (RF) and its sequel, Rheumatic Heart Disease (RHD) is a disease of significant medical and public health concern in the Federated States of Micronesia. In this preliminary study the feasibility of a rheumatic heart disease primary prevention strategy was examined. Throat swabs were taken from 667 school-aged children and tested for group A streptococci (GAS) by a rapid antigen detection test (RADT): a subset was also tested by conventional culture, so as to compare the RADT with the reference (conventional culture) test. GAS was detected in 124% of the children tested by either rapid antigen test or conventional culture; for RADT alone the detection rate was 11.5% and for culture alone the detection rate was 9.4%. Detection rate of GAS was analyzed in symptomatic and asymptomatic subgroups. The subgroups were compared using Fisher's exact method. The identification of children with GAS allows for their further examination and treatment so that the prevalence of GAS in this vulnerable population, currently with an annual incidence of rheumatic fever of 50-134/100,000, may be reduced. The routine testing of school-aged children appears to be possible with current resources in Kosrae and can be a cost-effective public health measure.

  17. A Competition Law Assessment of Platform Most-Favoured-Customer Clauses

    OpenAIRE

    Akman, P

    2016-01-01

    Most-favoured-customer (MFC) clauses adopted by online platforms in their relevant contractual relationships guarantee to an online platform that a supplier will treat the platform as favourably as the supplier’s most-favoured-customer concerning price, availability and similar terms of a given transaction. These clauses are a fundamental aspect of the business models of some of the world’s leading companies such as Apple, Amazon, Expedia, etc. The competition law implications of these clause...

  18. Experimental evidence for mutual inter- and intrasexual selection favouring a crested auklet ornament.

    Science.gov (United States)

    Jones; Hunter

    1999-03-01

    During the breeding season, female and male crested auklets Aethia cristatella (Alcidae), display similar conspicuous crest ornaments composed of elongated forward-curving feathers on their foreheads. Based on quantifications of brief agonistic interactions at a large breeding colony, we found that crest length was strongly correlated with dominance within both sexes. Across the full range of crest length, individuals with longer crests were dominant over shorter-crested individuals in agonistic interactions involving same-sex adults. Within subadults (2-year-olds of unknown sex), there was a similar trend towards longer-crested individuals being dominant. In agonistic interactions involving individuals of different sex and age, adult males were dominant over adult females and adults were dominant over subadults, regardless of crest length. In an experiment in which we manipulated crest length using life-size realistic models, male auklets that responded were less aggressive to male models with longer crests than to models with normal or shorter crests, confirming that crest length by itself signals dominance status. In a related experiment in which we controlled intrasexual competition, both males and females responded to opposite-sex models with more frequent sexual displays when the models had long crests compared with those having short crests, suggesting that crested auklets also have mating preferences that favour long crest ornaments. Taken together, these results support the idea that the crest ornament is favoured by both intra- and intersexual selection. Copyright 1999 The Association for the Study of Animal Behaviour.

  19. Order on programmes of assistance favouring emigrants, 15 January 1988.

    Science.gov (United States)

    1988-01-01

    This Order sets forth programs of assistance containing the following categories of aid: 1) aid for elderly emigrants who are Spanish or in the process of recovering Spanish citizenship and are ill and incapable of working; 2) aid to cover the extraordinary costs related to emigration or the return of Spanish emigrant workers and their families who are in a state of need; 3) aid to facilitate the integration into the workplace of returned Spanish emigrants who are unemployed; 4) aid for emigrant centers, associations, and federations helping Spanish emigrants; 5) aid to organizations to improve the assistance and hospital and cultural activities that they provide to Spanish emigrants; 6) aid to organizations that promote professional and occupational orientation and training to facilitate the professional promotion and insertion in the workplace of Spanish emigrant workers; 7) aid to Spanish emigrants and their families resident abroad who have special abilities and wish to pursue higher education and lack the means to do so in Spain; 8) aid to young Spanish emigrants resident abroad to promote their participation in cultural, sociocultural, artistic, and youth activities; 9) aid to promote the social integration of foreign workers in Spain; and 10) aid to programs involving the exchange of young workers within the European Economic Community. Further provisions of the Order deal with beneficiaries of aid, documentation required, and applications, among other things. This Order repeals provisions of an Order of 30 January 1987 (Boletin Oficial del Estado, No. 42, 18 February 1987, pp. 4952-4964) on the same topic in so far as those provisions are in conflict with the provisions of this Order.

  20. Federalism, Bicameralism, and Institutional Change: General Trends and One Case-study

    Directory of Open Access Journals (Sweden)

    Marta Arretche

    2010-12-01

    Full Text Available The article distinguishes federal states from bicameralism and mechanisms of territorial representation in order to examine the association of each with institutional change in 32 countries by using constitutional amendments as a proxy. It reveals that bicameralism tends to be a better predictor of constitutional stability than federalism. All of the bicameral cases that are associated with high rates of constitutional amendment are also federal states, including Brazil, India, Austria, and Malaysia. In order to explore the mechanisms explaining this unexpected outcome, the article also examines the voting behavior of Brazilian senators constitutional amendments proposals (CAPs. It shows that the Brazilian Senate is a partisan Chamber. The article concludes that regional influence over institutional change can be substantially reduced, even under symmetrical bicameralism in which the Senate acts as a second veto arena, when party discipline prevails over the cohesion of regional representation.

  1. Co-Relational Study of Achievement in Mathematics and Students' Academic Performance at the Federal College of Forestry

    Science.gov (United States)

    Appah, O. R.; Ojo, M. O.; Adegbite, R. A.; Adeniyi, O. S.; Oluwatayo, G. K.

    2014-01-01

    Mathematics serves as a strong reinforcement to most of the courses being offered at the Federal College of Forestry Ibadan, Oyo state, Nigeria. The knowledge gained from mathematics is expected to be applied to the courses offered in the College of Forestry. This study investigated the relationship between the students' score in mathematics and…

  2. Road Accident Analysis: A Case Study of Federal Route FT024 Yong Peng- Parit Sulong

    Directory of Open Access Journals (Sweden)

    Mohd Masirin Mohd Idrus

    2016-01-01

    Full Text Available Traffic accidents are considered as an unplanned and unfortunate event which is a serious concern to the community as well as the authority. An accident-counter measure can reduce the rate of road accidents by initially identifying critical locations. The total of road accidents along FT 024 between 2009 and 2012 is 907 cases. Road accidents during the same period range between 24 % and 26 % each year. These accidents killed 34 people and injuring another 101 people. This research aims to identify factors that may contribute to the cause of accidents and to study the effects of speed, volume and road geometry on road accidents. In this study, the locations labelled as km 1, km 2, km 4, km 8, km 5 and km 14 of Federal Route FT 024 Yong Peng – Parit Sulong were selected as the study-case sections based on Accident Point Weightage of ranking, in which each location has different road characteristics. Speed study was carried out at selected road sections to evaluate the influence of speed upon road accidents; and traffic volume count was conducted at the same selected road sections to determine the existing condition of the route. Besides, road geometry observations and measurements were also conducted at selected sections, they were also studied to evaluate influence of road designs upon road accidents. The extracted data were analyzed by using regression analysis on different variables to evaluate the relationship between accident Weightage point and other dependent variables that were considered to have considerable effects upon road accidents such as mean speed, volume, shoulder width, lane width and access point. P value below 0.05 was considered as statistically significant. After conducting data analysis, this study showed that the number of road accidents increases with the increment of speed and access point. On the other hand, volume has no strong relationship to road accidents which means that it may not have an effect on accidents

  3. 1996 Lead Shot Study of Upland Habitat on North Dakota's Federal Trust Resource Land

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 1996 the U.S. Fish and Wildlife Service (Service) collected field data to determine the extent of lead shot deposition on upland areas of North Dakota’s Federal...

  4. Monitoring study of the quality of work with gifted schoolchildren in the Russian Federation regions

    Directory of Open Access Journals (Sweden)

    Aleksandr Vyacheslavovich Chegodaev

    2014-05-01

    Full Text Available The article presents the results of research into the quality of work with talented schoolchildren in the Russian Federation subjects. It shows that it is the regional and municipal levels that should be most actively involved in the identification and development of such children. The author suggests his methodology of calculating the integral index of the quality of work with gifted schoolchildren in the regional educational systems. The article shows that Russia’s territories differ considerably according to this indicator. The highest value of the index is registered in the Volga Federal District (average rating is 0.499 and the Central (0.480 Federal District. The constituent entities of the North Caucasian (0.303 and Far Eastern (0.358 federal districts have the lowest average rating. The regions were divided into five groups by the index of quality of work with gifted schoolchildren. The Vologda Oblast joined the group in which the level of quality of work with gifted schoolchildren was above average; the Oblast ranked 22nd in the country and 5th in the Northwestern Federal District. The Oblast has the greatest progress by the set of indicators “Olympiad movement” (6th place among Russian regions. According to some indicators, the Oblast’s results were below the threshold indicators. The dynamics of the integral index of the quality of work with gifted students for 2012–2013 was analysed by the cross grouping of the regions according to the level and rate of growth (decline of the integral index. The Vologda Oblast was included in the group of regions with low growth rates of the integral index (94%, which creates the risk of decrease in the quality of work with gifted students. The article states the main reasons for the integral index decline; it also suggests certain measures for the improvement of the quality of work with gifted schoolchildren

  5. Federal Lands

    Data.gov (United States)

    Department of Homeland Security — This map layer consists of federally owned or administered lands of theUnited States, Puerto Rico, and the U.S. Virgin Islands. Only areas of 640 acres or more are...

  6. Why increasing longevity may favour a PAYG pension system over a funded system.

    Science.gov (United States)

    Ediev, Dalkhat M

    2014-03-01

    When pension systems are contrasted it is common to use simplified demographic models, such as overlapping generation models with time-invariant mortality. Breaking with this tradition, we show that for a population with increasing longevity, the pay-as-you-go (PAYG) system may be more advantageous than a funded system (FS). Increasing longevity favours the PAYG system because for the workers living longer at retirement than current retirees, it is less costly to fund others' current pensions than their own. At present, the effect amounts to around 15 per cent in terms of the dependency ratio, or six more years at work in the FS, or 1 per cent per annum in terms of the real interest rate. In most developed countries the effect substantially exceeds that of the usually studied biological interest rate.

  7. Phosphorylation controls the functioning of Staphylococcus aureus isocitrate dehydrogenase--favours biofilm formation.

    Science.gov (United States)

    Prasad, U Venkateswara; Vasu, D; Yeswanth, S; Swarupa, V; Sunitha, M M; Choudhary, A; Sarma, P V G K

    2015-01-01

    Isocitrate dehydrogenase (IDH) gene from Staphylococcus aureus ATCC12600 was cloned, sequenced and characterized (HM067707). PknB site was observed in the active site of IDH; thus, it was predicted as IDH may be regulated by phosphorylation. Therefore, in this study, PknB, alkaline phosphatase III (SAOV 2675) and IDH genes (JN695616, JN645811 and HM067707) of S. aureus ATCC12600 were over expressed from clones PV 1, UVPALP-3 and UVIDH 1. On passing the cytosloic fractions through nickel metal chelate column, pure enzymes were obtained. Phosphorylation of pure IDH by PknB resulted in the complete loss of activity and was restored upon dephosphorylation with SAOV 2675 which indicated that phosphorylation and dephosphorylation regulate IDH activity in S. aureus. Further, when S. aureus ATCC12600 was grown in BHI broth, decreased IDH activity and increased biofilm units were observed; therefore, this regulation of IDH alters redox status in this pathogen favouring biofilm formation.

  8. What does a study of nonsteroidal anti-inflammatory drug sales statistics give the Russian Federation?

    Directory of Open Access Journals (Sweden)

    Viktoriya Georgievna Barskova

    2011-01-01

    Full Text Available The paper analyzes the data obtained by Pharmexpert on the sales of nonsteroidal anti-inflammatory drugs in the Russian Federation. Ibuprofen, ketorolac, diclofenac, and nimesulide are sales leaders. Possible reasons for the popularity of a number of medications and whether it is expedient to use intramuscular formulations are considered. The WHO data on indi-cations for and contraindications to the use of injectable dosage form are given.

  9. Sleep to the beat : A nap favours consolidation of timing

    NARCIS (Netherlands)

    Verweij, Ilse M; Onuki, Yoshiyuki; Van Someren, Eus J W; Van der Werf, Ysbrand D

    Growing evidence suggests that sleep is important for procedural learning, but few studies have investigated the effect of sleep on the temporal aspects of motor skill learning. We assessed the effect of a 90-min day-time nap on learning a motor timing task, using 2 adaptations of a serial

  10. Sleep to the beat : A nap favours consolidation of timing

    NARCIS (Netherlands)

    Verweij, Ilse M; Onuki, Yoshiyuki; Van Someren, Eus J W; Van der Werf, Ysbrand D

    2016-01-01

    Growing evidence suggests that sleep is important for procedural learning, but few studies have investigated the effect of sleep on the temporal aspects of motor skill learning. We assessed the effect of a 90-min day-time nap on learning a motor timing task, using 2 adaptations of a serial intercept

  11. Does displayed enthusiasm favour recall, intrinsic motivation and time estimation?

    Science.gov (United States)

    Moè, Angelica

    2016-11-01

    Displayed enthusiasm has been shown to relate to intrinsic motivation, vitality, and positive affect, but its effects on recall performance and time estimation have not yet been explored. This research aimed at studying the effects of a delivery style characterised by High Enthusiasm (HE) on recall, time estimation, and intrinsic motivation. In line with previous studies, effects on intrinsic motivation were expected. In addition, higher recall and lower time estimations were hypothesised. In two experiments, participants assigned to a HE condition or to a normal reading control condition listened to a narrative and to a descriptive passage. Then, they were asked to rate perceived time, enthusiasm, pleasure, interest, enjoyment and curiosity, before writing a free recall. Experiment 1 showed that in the HE condition, participants recalled more, were more intrinsically motivated, and expressed lower time estimations compared to the control condition. Experiment 2 confirmed the positive effects of HE reading compared to normal reading, using different passages and a larger sample.

  12. The favourable large misorientation angle grain boundaries in graphene.

    Science.gov (United States)

    Zhang, Xiuyun; Xu, Ziwei; Yuan, Qinghong; Xin, John; Ding, Feng

    2015-12-21

    A grain boundary (GB) in graphene is a linear defect between two specifically oriented graphene edges, whose title angles are denoted as θ1 and θ2, respectively. Here we present a systematic theoretical study on the structure and stability of GBs in graphene as a function of the misorientation angle, Φ = (θ1-θ2) and the GB orientation in multi-crystalline graphene, which is denoted by Θ = (θ1 + θ2). It is surprising that although the number of disorders of the GB, i.e., the pentagon-heptagon pairs (5|7s), reaches the maximum at Φ∼ 30°, the GB formation energy versus the Φ curve reaches a local minimum. The subsequent M-shape of the Efvs. the Φ curve is due to the strong cancellation of the local strains around 5|7 pairs by the "head-to-tail" formation. This study successfully explains many previously observed experimental puzzles, such as the multimodal distribution of GBs and the abundance of GB misorientation angles of ∼30°. Besides, this study also showed that the formation energy of GBs is less sensitive to Θ, although the twin boundaries are slightly more stable than others.

  13. Plastic traits of an exotic grass contribute to its abundance but are not always favourable.

    Directory of Open Access Journals (Sweden)

    Jennifer Firn

    Full Text Available In herbaceous ecosystems worldwide, biodiversity has been negatively impacted by changed grazing regimes and nutrient enrichment. Altered disturbance regimes are thought to favour invasive species that have a high phenotypic plasticity, although most studies measure plasticity under controlled conditions in the greenhouse and then assume plasticity is an advantage in the field. Here, we compare trait plasticity between three co-occurring, C(4 perennial grass species, an invader Eragrostis curvula, and natives Eragrostis sororia and Aristida personata to grazing and fertilizer in a three-year field trial. We measured abundances and several leaf traits known to correlate with strategies used by plants to fix carbon and acquire resources, i.e. specific leaf area (SLA, leaf dry matter content (LDMC, leaf nutrient concentrations (N, C:N, P, assimilation rates (Amax and photosynthetic nitrogen use efficiency (PNUE. In the control treatment (grazed only, trait values for SLA, leaf C:N ratios, Amax and PNUE differed significantly between the three grass species. When trait values were compared across treatments, E. curvula showed higher trait plasticity than the native grasses, and this correlated with an increase in abundance across all but the grazed/fertilized treatment. The native grasses showed little trait plasticity in response to the treatments. Aristida personata decreased significantly in the treatments where E. curvula increased, and E. sororia abundance increased possibly due to increased rainfall and not in response to treatments or invader abundance. Overall, we found that plasticity did not favour an increase in abundance of E. curvula under the grazed/fertilized treatment likely because leaf nutrient contents increased and subsequently its' palatability to consumers. E. curvula also displayed a higher resource use efficiency than the native grasses. These findings suggest resource conditions and disturbance regimes can be manipulated to

  14. Cervicofacial necrotizing fasciitis: can we expect a favourable outcome?

    Science.gov (United States)

    Panda, Naresh K; Simhadri, Sridhar; Sridhara, Suryanarayana Rao

    2004-10-01

    Necrotizing fasciitis of the head and neck is an uncommon, progressive, destructive soft tissue infection of mixed aerobic and anaerobic organisms, having high mortality if left untreated (22 to 100 per cent). This study makes an attempt to analyse various factors and management methods determining the overall prognosis. A retrospective analysis of all cases of necrotizing fasciitis involving the head and neck, with exclusion of those involving the eyelid and the scalp, was undertaken. Various parameters such as demography, aetiology, complications, management and outcome were studied. Males outnumbered the females with the latter having a greater risk of involvement after 60 years. Odontogenic infection was the primary source of infection. Anaerobes were cultured in seven out of 17 cases, with six others showing mixed Gram positive and Gram negative organisms. Anaemia was the most commonly associated illness, with diabetes affecting four out of 17 cases. Aggressive surgical debridement with triple antibiotic therapy was used in the management of necrotizing fasciitis with an overall mortality of 11.8 per cent. Patients having late referral, anaemia and one or other complication had increased duration of total hospital stay. Better results can be obtained with proper control of infection by early diagnosis, aggressive surgical debridement and triple antibiotic therapy, along with timely control of complications and associated illnesses.

  15. Natural selection can favour ‘irrational’ behaviour

    Science.gov (United States)

    McNamara, J. M.; Trimmer, P. C.; Houston, A. I.

    2014-01-01

    Understanding decisions is the fundamental aim of the behavioural sciences. The theory of rational choice is based on axiomatic principles such as transitivity and independence of irrelevant alternatives (IIA). Empirical studies have demonstrated that the behaviour of humans and other animals often seems irrational; there can be a lack of transitivity in choice and seemingly irrelevant alternatives can alter decisions. These violations of transitivity and IIA undermine rational choice theory. However, we show that an individual that is maximizing its rate of food gain can exhibit failure of transitivity and IIA. We show that such violations can be caused because a current option may disappear in the near future or a better option may reappear soon. Current food options can be indicative of food availability in the near future, and this key feature can result in apparently irrational behaviour. PMID:24429682

  16. HPV status and favourable outcome in vulvar squamous cancer.

    Science.gov (United States)

    Wakeham, Katie; Kavanagh, Kim; Cuschieri, Kate; Millan, David; Pollock, Kevin G; Bell, Sarah; Burton, Kevin; Reed, Nicholas S; Graham, Sheila V

    2017-03-01

    It is universally accepted that high-risk human papillomavirus (HR-HPV) is the cause of cervical dysplasia and cancer. More recently, it has been shown that HPV is also a marker of clinical outcome in oropharyngeal cancer. However, contemporary information is lacking on both the prevalence of HPV infection in vulvar cancer (VSCC), its precursor lesion, vulvar intraepithelial neoplasia (VIN) and the influence of HPV-status on the prognosis of this malignancy. We have conducted a detailed population-based study to examine rates of progression of VIN to VSCC, type-specific HPV prevalence in vulvar disease and the influence of HPV status on clinical outcome in VSCC. We observed that the age at which women are diagnosed with VSCC is falling and there is a significant time gap between first diagnosis of VIN and progression to invasive disease. HR-HPV infection was detected in 87% (97/112) cases of VIN and 52% cases (32/62) of VSCC. The presence of HR-HPV in squamous intraepithelial lesion was associated with lower rates of progression to invasive cancer (hazard ratio, 0.22, p = 0.001). In the adjusted analysis, HR-HPV was associated with improved progression-free survival of VSCC compared to those with HPV negative tumours (hazard ratio, 0.32, p = 0.02).

  17. Protist predation can favour cooperation within bacterial species

    Science.gov (United States)

    Friman, Ville-Petri; Diggle, Stephen P.; Buckling, Angus

    2013-01-01

    Here, we studied how protist predation affects cooperation in the opportunistic pathogen bacterium Pseudomonas aeruginosa, which uses quorum sensing (QS) cell-to-cell signalling to regulate the production of public goods. By competing wild-type bacteria with QS mutants (cheats), we show that a functioning QS system confers an elevated resistance to predation. Surprisingly, cheats were unable to exploit this resistance in the presence of cooperators, which suggests that resistance does not appear to result from activation of QS-regulated public goods. Instead, elevated resistance of wild-type bacteria was related to the ability to form more predation-resistant biofilms. This could be explained by the expression of QS-regulated resistance traits in densely populated biofilms and floating cell aggregations, or alternatively, by a pleiotropic cost of cheating where less resistant cheats are selectively removed from biofilms. These results show that trophic interactions among species can maintain cooperation within species, and have further implications for P. aeruginosa virulence in environmental reservoirs by potentially enriching the cooperative and highly infective strains with functional QS system. PMID:23945212

  18. Initial community evenness favours functionality under selective stress.

    Science.gov (United States)

    Wittebolle, Lieven; Marzorati, Massimo; Clement, Lieven; Balloi, Annalisa; Daffonchio, Daniele; Heylen, Kim; De Vos, Paul; Verstraete, Willy; Boon, Nico

    2009-04-01

    Owing to the present global biodiversity crisis, the biodiversity-stability relationship and the effect of biodiversity on ecosystem functioning have become major topics in ecology. Biodiversity is a complex term that includes taxonomic, functional, spatial and temporal aspects of organismic diversity, with species richness (the number of species) and evenness (the relative abundance of species) considered among the most important measures. With few exceptions (see, for example, ref. 6), the majority of studies of biodiversity-functioning and biodiversity-stability theory have predominantly examined richness. Here we show, using microbial microcosms, that initial community evenness is a key factor in preserving the functional stability of an ecosystem. Using experimental manipulations of both richness and initial evenness in microcosms with denitrifying bacterial communities, we found that the stability of the net ecosystem denitrification in the face of salinity stress was strongly influenced by the initial evenness of the community. Therefore, when communities are highly uneven, or there is extreme dominance by one or a few species, their functioning is less resistant to environmental stress. Further unravelling how evenness influences ecosystem processes in natural and humanized environments constitutes a major future conceptual challenge.

  19. 1988 Federal Interim Storage Fee study: A technical and economic analysis

    Energy Technology Data Exchange (ETDEWEB)

    1988-11-01

    This document is the latest in a series of reports that are published annually by Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). The information in this report, which was prepared by E.R. Johnson Associates, Inc., under subcontract to PNL, will be used by the DOE to establish a payment schedule for interim storage of spent nuclear fuel under the Federal Interim Storage (FIS) Program. The FIS Program was mandated by the Nuclear Waste Policy Act of 1982. The information will be used to establish the schedule of charges for FIS services for the year commencing January 1, 1989. 13 refs.

  20. 1987 Federal interim storage fee study: A technical and economic analysis

    Energy Technology Data Exchange (ETDEWEB)

    1987-09-01

    This document is the latest in a series of reports that are published annually by Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE). This information in the report, which was prepared by E.R. Johnson Associates under subcontract to PNL, will be used by the DOE to establish a payment schedule for interim storage of spent nuclear fuel under the Federal Interim Storage (FIS) Program, which was mandated by the Nuclear Waste Policy Act of 1982. The information in this report will be used to establish the schedule of charges for FIS services for the year commencing January 1, 1988. 13 tabs.

  1. Transparency of information of federal universities: study of management reports in light of governance principles

    Directory of Open Access Journals (Sweden)

    Luzia Zorzal

    2016-03-01

    Full Text Available This article is based on a doctoral research in Information Science which examines to what extent Management Reports of Federal Universities meet the governance principles established for the public sector, according to national and international guidelines. It is exploratory, descriptive, qualitative research whose interpretation of the data it is anchored on content analysis. It has as universe the 63 Brazilian federal universities, of which those that were ranked at the top of Ranking Webometrics, in each of the five geographic regions were selected. Results show that the five analyzed universities do not reach a high transparency level. Two universities ranked in the medium-high level and three in medium-low level. The compliance with principles of good governance on the Management Reports of these universities is still insufficient to achieve the highest level of transparency. The data show that to improve this profile to increase the active transparency under Brazilian law on access to information and the dissemination of information needs to be timely, with clarity and accuracy implanting good governance practices is necessary. Such initiative could mitigate informational asymmetry and democratize the relationship between State and citizens.

  2. Fiscal Federalism

    DEFF Research Database (Denmark)

    Feng, Xingyuan; Ljungwall, Christer; Guo, Sujian

    2013-01-01

    in the Western literature? Second, are there any problems with existing principles of fiscal federalism and, if so, how to refine them? Third, how are refined principles relevant to the Chinese case and what policies should the Chinese government pursue in the future? Based on an in-depth and critical review...... relations is not without controversy. This paper aims to make a theoretical contribution to the ongoing debate on ‘fiscal federalism’ by addressing crucial questions regarding China's central–local fiscal relations: first, to what extent do Chinese central–local fiscal relations conform to fiscal federalism...

  3. PingFederate

    Data.gov (United States)

    US Agency for International Development — PingFederate Server provides Identity Federation and Single Sign On Capabilities. Federated identity management (or identity federation) enables enterprises to...

  4. Creeping Federalization

    DEFF Research Database (Denmark)

    Sweeney, Richard J.

    2003-01-01

    that make taxharmonization difficult to impose. Other types of harmonization have a less clear-cut costbenefitanalysis. A federal commercial code that is uniform across member states reducestransaction and information costs, compared to leaving important code issues to memberstates; further, many states may...

  5. Conceptions of Software Development by Project Managers: A Study of Managing the Outsourced Development of Software Applications for United States Federal Government Agencies

    Science.gov (United States)

    Eisen, Daniel

    2013-01-01

    This study explores how project managers, working for private federal IT contractors, experience and understand managing the development of software applications for U.S. federal government agencies. Very little is known about how they manage their projects in this challenging environment. Software development is a complex task and only grows in…

  6. A Multi-Level Investigation into the Antecedents of Enterprise Architecture (EA) Assimilation in the U.S. Federal Government: A Longitudinal Mixed Methods Research Study

    Science.gov (United States)

    Makiya, George K.

    2012-01-01

    This dissertation reports on a multi-dimensional longitudinal investigation of the factors that influence Enterprise Architecture (EA) diffusion and assimilation within the U.S. federal government. The study uses publicly available datasets of 123 U.S. federal departments and agencies, as well as interview data among CIOs and EA managers within…

  7. A Multi-Level Investigation into the Antecedents of Enterprise Architecture (EA) Assimilation in the U.S. Federal Government: A Longitudinal Mixed Methods Research Study

    Science.gov (United States)

    Makiya, George K.

    2012-01-01

    This dissertation reports on a multi-dimensional longitudinal investigation of the factors that influence Enterprise Architecture (EA) diffusion and assimilation within the U.S. federal government. The study uses publicly available datasets of 123 U.S. federal departments and agencies, as well as interview data among CIOs and EA managers within…

  8. Conceptions of Software Development by Project Managers: A Study of Managing the Outsourced Development of Software Applications for United States Federal Government Agencies

    Science.gov (United States)

    Eisen, Daniel

    2013-01-01

    This study explores how project managers, working for private federal IT contractors, experience and understand managing the development of software applications for U.S. federal government agencies. Very little is known about how they manage their projects in this challenging environment. Software development is a complex task and only grows in…

  9. Vocational Education and Training for the Hotel and Catering Industry in the Federal Republic of Germany. Report of a Visiting Party. Studies in Vocational Education and Training in the Federal Republic of Germany. Number Eight.

    Science.gov (United States)

    Ripper, Chris, Ed.; Russell, Russ, Ed.

    A party of vocational educators from the United Kingdom (UK) traveled to the Federal Republic of Germany (FRG) to examine West German vocational education and training for the hotel and catering industry. During the study, the investigators examined the training with respect to regulations, the content of training, and the structure of the…

  10. Vocational Education and Training for the Hotel and Catering Industry in the Federal Republic of Germany. Report of a Visiting Party. Studies in Vocational Education and Training in the Federal Republic of Germany. Number Eight.

    Science.gov (United States)

    Ripper, Chris, Ed.; Russell, Russ, Ed.

    A party of vocational educators from the United Kingdom (UK) traveled to the Federal Republic of Germany (FRG) to examine West German vocational education and training for the hotel and catering industry. During the study, the investigators examined the training with respect to regulations, the content of training, and the structure of the…

  11. Meta-analysis of phenotypic selection on flowering phenology suggests that early flowering plants are favoured.

    Science.gov (United States)

    Munguía-Rosas, Miguel A; Ollerton, Jeff; Parra-Tabla, Victor; De-Nova, J Arturo

    2011-05-01

    Flowering times of plants are important life-history components and it has previously been hypothesized that flowering phenologies may be currently subject to natural selection or be selectively neutral. In this study we reviewed the evidence for phenotypic selection acting on flowering phenology using ordinary and phylogenetic meta-analysis. Phenotypic selection exists when a phenotypic trait co-varies with fitness; therefore, we looked for studies reporting an association between two components of flowering phenology (flowering time or flowering synchrony) with fitness. Data sets comprising 87 and 18 plant species were then used to assess the incidence and strength of phenotypic selection on flowering time and flowering synchrony, respectively. The influence of dependence on pollinators, the duration of the reproductive event, latitude and plant longevity as moderators of selection were also explored. Our results suggest that selection favours early flowering plants, but the strength of selection is influenced by latitude, with selection being stronger in temperate environments. However, there is no consistent pattern of selection on flowering synchrony. Our study demonstrates that phenotypic selection on flowering time is consistent and relatively strong, in contrast to previous hypotheses of selective neutrality, and has implications for the evolution of temperate floras under global climate change. © 2011 Blackwell Publishing Ltd/CNRS.

  12. Introduction to the integrated environmental management: a case study at the federal office of brazilian research

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Maria Cecilia Cavalcante da, E-mail: msilva@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, RJ (Brazil)

    2013-07-01

    The globalization process establishment has been a major impulse for profound transformations as to environmental issues in the social, political and economic scenario of both industrialized and developing countries. Within this scope, the concern with climate changes, global warming, biodiversity, population growth and public health have promoted the dissemination of environmental values and the induction to a community participative culture. Notwithstanding, a growing demand by the society related to the environment and social issues has been evidenced, converging the environmental theme to a holistic approach and, also, to the life quality concern. Therefore, private and public organizations have given more attention to issues involving their internal and external clients and/or users, in view of their products or services and social aspects, including those covering their workers and collaborators health and safety: with this overall purpose, an Integrated Management System (IMS) for Quality, Environment, Health and Safety was created. This management policy has been, commonly, employed in the private sector, even though a small, but yet expressive part of it refers to the public area. In face of this scenario, it may be foreseen that the motivations for adopting such management tool and the methods used for this goal may differ, according to the economic context. Under this point of view, this work had the target of analyzing, qualitatively, the process of setting the IMS in a federal. Eventually, a targeted result was to identify advantages and disadvantages for a public institution. (author)

  13. Airborne Quercus pollen in SW Spain: Identifying favourable conditions for atmospheric transport and potential source areas.

    Science.gov (United States)

    Maya-Manzano, José María; Fernández-Rodríguez, Santiago; Smith, Matt; Tormo-Molina, Rafael; Reynolds, Andrew M; Silva-Palacios, Inmaculada; Gonzalo-Garijo, Ángela; Sadyś, Magdalena

    2016-11-15

    The pollen grains of Quercus spp. (oak trees) are allergenic. This study investigates airborne Quercus pollen in SW Spain with the aim identifying favourable conditions for atmospheric transport and potential sources areas. Two types of Quercus distribution maps were produced. Airborne Quercus pollen concentrations were measured at three sites located in the Extremadura region (SW Spain) for 3 consecutive years. The seasonal occurrence of Quercus pollen in the air was investigated, as well as days with pollen concentrations ≥80Pm(-3). The distance that Quercus pollen can be transported in appreciable numbers was calculated using clusters of back trajectories representing the air mass movement above the source areas (oak woodlands), and by using a state-of-the-art dispersion model. The two main potential sources of Quercus airborne pollen captured in SW Spain are Q. ilex subsp. ballota and Q. suber. The minimum distances between aerobiological stations and Quercus woodlands have been estimated as: 40km (Plasencia), 66km (Don Benito), 62km (Zafra) from the context of this study. Daily mean Quercus pollen concentration can exceed 1,700Pm(-3), levels reached not less than 24 days in a single year. High Quercus pollen concentration were mostly associated with moderate wind speed events (6-10ms(-1)), whereas that a high wind speed (16-20ms(-1)) seems to be associated with low concentrations.

  14. Geological Conditions Favourable for High-Wax Oil Enrichment in Damintun Depression,Bohai Bay Basin

    Institute of Scientific and Technical Information of China (English)

    Zhu Fangbing

    2009-01-01

    The Damintun (大民屯) depression,a small (about 800 km2 in area) subunit in the Bohai (渤海) Bay basin,hosts nearly 2×108t of high-wax oils with wax contents up to 60%. The high-wax oils have high consolidation temperatures and viscosities.The high-wax oils were generated from the fourth member of the Shahejie Formation (Es4),which is also important source rocks for oils in other subunits of the Bohai Bay basin.Yet high-wax oils have not been found in significant volumes elsewhere in the Bohai Bay basin.Geological conditions favourable for high-wax oil enrichment were studied.This study shows that the unusual concentrations of high-wax oils in the depression seem to result from at least three different factors: (1) the presence of organic-matter rich source rocks which were prone to generate wax-rich hydrocarbons; (2) the formation of early overpressures which increased the expulsion efficiency of waxy hydrocarbons; and (3) reductions in subsidence rate and basal heat flows,which minimized the thermal cracking of high molecular-weight (waxy) hydrocarbons,and therefore prevented the high-wax oils from being transformed into less waxy equivalents.

  15. ESIP Federation: A Case Study on Enabling Collaboration Infrastructure to Support Earth Science Informatics Communities

    Science.gov (United States)

    Robinson, E.; Meyer, C. B.; Benedict, K. K.

    2013-12-01

    A critical part of effective Earth science data and information system interoperability involves collaboration across geographically and temporally distributed communities. The Federation of Earth Science Information Partners (ESIP) is a broad-based, distributed community of science, data and information technology practitioners from across science domains, economic sectors and the data lifecycle. ESIP's open, participatory structure provides a melting pot for coordinating around common areas of interest, experimenting on innovative ideas and capturing and finding best practices and lessons learned from across the network. Since much of ESIP's work is distributed, the Foundation for Earth Science was established as a non-profit home for its supportive collaboration infrastructure. The infrastructure leverages the Internet and recent advances in collaboration web services. ESIP provides neutral space for self-governed groups to emerge around common Earth science data and information issues, ebbing and flowing as the need for them arises. As a group emerges, the Foundation quickly equips the virtual workgroup with a set of ';commodity services'. These services include: web meeting technology (Webex), a wiki and an email listserv. WebEx allows the group to work synchronously, dynamically viewing and discussing shared information in real time. The wiki is the group's primary workspace and over time creates organizational memory. The listserv provides an inclusive way to email the group and archive all messages for future reference. These three services lower the startup barrier for collaboration and enable automatic content preservation to allow for future work. While many of ESIP's consensus-building activities are discussion-based, the Foundation supports an ESIP testbed environment for exploring and evaluating prototype standards, services, protocols, and best practices. After community review of testbed proposals, the Foundation provides small seed funding and a

  16. Donor's age and replicative senescence favour the in-vitro mineralization potential of human fibroblasts.

    Science.gov (United States)

    Boraldi, Federica; Bartolomeo, Angelica; Di Bari, Caterina; Cocconi, Andrea; Quaglino, Daniela

    2015-12-01

    Aberrant mineralization of soft connective tissues (ectopic calcification) may occur as a frequent age-related complication. Still, it remains unclear the role of mesenchymal cell donor's age and of replicative senescence on ectopic calcification. Therefore, the ability of cells to deposit in-vitro hydroxyapatite crystals and the expression of progressive ankylosis protein homolog (ANKH), ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), tissue non specific alkaline phosphatase (TNAP) and osteopontin (OPN) have been evaluated in human dermal fibroblasts derived from neonatal (nHDF) and adult (aHDF) donors (ex-vivo ageing model) or at low and high cumulative population doublings (CPD) up to replicative senescence (in-vitro ageing model). This study demonstrates that: 1) replicative senescence favours hydroxyapatite formation in cultured fibroblasts; 2) donor's age acts as a major modulator of the mineralizing potential of HDF, since nHDF are less prone than aHDF to induce calcification; 3) donor's age and replicative senescence play in concert synergistically increasing the calcification process; 4) the ANKH+ENPP1/TNAP ratio, being crucial for pyrophosphate/inorganic phosphate balance, is greatly influenced by donor's age, as well as by replicative senescence, and regulates mineral deposition; 5) OPN is only modulated by replicative senescence.

  17. Is earthquake activity along the French Atlantic margin favoured by local rheological contrasts?

    Science.gov (United States)

    Mazabraud, Yves; Béthoux, Nicole; Delouis, Bertrand

    2013-09-01

    The seismological study of recent seismic crises near Oleron Island confirms the coexistence of an extensional deformation and a transtensive regime in the Atlantic margin of France, which is different from the general western European stress field corresponding to a strike-slip regime. We argue that the switch of the principal stress axes σ1/σ2 in a NW-SE vertical plane is linked with the existence of crustal heterogeneities. Events of magnitude larger than 5 sometimes occur along the Atlantic margin of France, such as the 7 September 1972 (ML = 5.2) earthquake near Oleron island and the 30 September 2002 (ML = 5.7) Hennebont event in Brittany. To test the mechanism of local strain localization, we model the deformation of the hypocentral area of the Hennebont earthquake using a 3D thermo-mechanical finite element code. We conclude that the occurrence of moderate earthquakes located in limited parts of the Hercynian shear zones (as the often reactivated swarms near Oleron) could be due to local reactivation of pre-existing faults. These sporadic seismic ruptures are favoured by stress concentration due to rheological heterogeneities.

  18. The Progenitors of the Milky Way Stellar Halo: Big Bricks Favoured over Little Bricks

    CERN Document Server

    Deason, A J; Weisz, D R

    2015-01-01

    We present a census of blue horizontal branch (BHB) and blue straggler (BS) stars belonging to dwarf galaxies and globular clusters, and compare these counts to that of the Milky Way stellar halo. We find, in agreement with earlier studies, that the ratio of BS-to-BHB stars in these satellite populations is dependent on stellar mass. Dwarf galaxies show an increasing BS-to-BHB ratio with luminosity. In contrast, globular clusters display the reverse trend, with N_BS/N_BHB (< 1) decreasing with luminosity. The faintest (L < 10^5 L_Sun) dwarfs have similar numbers of BS and BHB stars (N_BS/N_BHB ~ 1), whereas more massive dwarfs tend to be dominated by BS stars (N_BS/N_BHB ~ 2-40). We find that the BS-to-BHB ratio in the stellar halo is relatively high (N_BS/N_BHB ~ 5-6), and thus inconsistent with the low ratios found in both ultra-faint dwarfs and globular clusters. Our results favour more massive dwarfs as the dominant "building blocks" of the stellar halo, in good agreement with current predictions fr...

  19. Learning styles favoured by professional, amateur, and recreational athletes in different sports.

    Science.gov (United States)

    González-Haro, Carlos; Calleja-González, Julio; Escanero, Jesus F

    2010-06-01

    The aim of this study was to characterize the learning styles of different groups of athletes grouped according to level of performance and sport. Seventy-one male athletes completed a questionnaire on learning styles at the beginning of the 2008-2009 training season. Learning styles were assessed using the Honey-Alonso Learning Styles Questionnaire, and were also converted into learning styles described by Kolb. The Honey-Alonso learning styles were compared among the various groups using one-way analysis of variance, and the Kolb learning styles that were most favoured using a chi-square test. Pearson's correlation coefficient was used to verify the relationships between variables. No significant differences were observed in learning styles between different sports and physical activities. Years of experience did not correlate strongly with learning styles. With respect to level of performance, the pragmatic component was significantly lower in professional athletes than amateur and recreational athletes. These characteristics of learning styles preferred by the athletes should help coaches and physical trainers to reflect on their role as educators in the context of planning sports training.

  20. Living with strangers: direct benefits favour non-kin cooperation in a communally nesting bird.

    Science.gov (United States)

    Riehl, Christina

    2011-06-07

    The greater ani (Crotophaga major), a Neotropical cuckoo, exhibits an unusual breeding system in which several socially monogamous pairs lay eggs in a single nest and contribute care to the communal clutch. Cooperative nesting is costly-females compete for reproduction by ejecting each other's eggs-but the potential direct or indirect fitness benefits that might accrue to group members have not been identified. In this study, I used molecular genotyping to quantify patterns of genetic relatedness and individual reproductive success within social groups in a single colour-banded population. Microsatellite analysis of 122 individuals in 49 groups revealed that group members are not genetic relatives. Group size was strongly correlated with individual reproductive success: solitary pairs were extremely rare and never successful, and nests attended by two pairs were significantly more likely to be depredated than were nests attended by three pairs. Egg loss, a consequence of reproductive competition, was greater in large groups and disproportionately affected females that initiated laying. However, early-laying females compensated for egg losses by laying larger clutches, and female group members switched positions in the laying order across nesting attempts. The greater ani, therefore, appears to be one of the few species in which cooperative breeding among unrelated individuals is favoured by direct, shared benefits that outweigh the substantial costs of reproductive competition.

  1. Study the Attitude, Knowledge and Experience of Coaches of Karate Federation Islamic Republic Of Iran toward Sport Psychology Counseling

    Directory of Open Access Journals (Sweden)

    Shahnaz Sheikh Rahmati

    2017-04-01

    Full Text Available The purpose of this study was study the attitude, knowledge and experience of coaches of Karate Federation Islamic Republic of Iran toward sport psychology counseling. For this purpose, 150 official coaches (75 women and 75 men of karate Federation of Islamic Republic of Iran who had grade 1 and 2 of certified coach and had participated in the senior Championships of Iran, championship adolescents of young people and under 21 years, national team qualifiers and teams participating in premier League, had participated in this research as individual. In order to collect the required information the researcher made and the research questionnaire Sports coaches on sports psychology was used. Research results by using a two variable Pearson correlation coefficient showed that there is meaningful relationship between experience and attitude to sport psychology consulting and as well as between knowledge and attitudes toward sport psychology consulting that is (p=0.001,p=0.001 respectively. also results of research using independent t-tests showed that there is not meaningful relationship between male and female attitudes towards sport psychology consulting (p=0.207 while there is meaningful difference between adult and youth educators' attitudes towards sports psychology counseling (p=0.001. It seems that according to common concerns that exist between coaches and athletes perhaps existence sport psychology can be effective to athletes and coaches in reducing stress and achieve the desired result.

  2. The organizational climate in university libraries: a study of sectoral libraries of the Federal University of Pernambuco

    Directory of Open Access Journals (Sweden)

    Andréa Maria da Silva

    2015-11-01

    Full Text Available Objective. This study investigates the perceptions of organizational climate of the employees working in the sector libraries at the Federal University of Pernambuco, in relation to leadership, communication, motivation and teamwork. Method. To achieve the proposed objective a survey was conducted with a questionnaire being answered by forty employees, viewing information on the organizational climate experienced in the sector libraries. Results. The main results of the survey indicated a predominantly satisfactory organizational climate in the analyzed libraries, considering that the organizational atmosphere proved to be sound, mingled with leaders and their teams, open to dialogue with professionals conducive to exercise a job competently. Conclusions. It is understood that the study of organizational climate in academic libraries is of paramount importência in order libraries are living, social and active organizations composed of human, technological, material, financial, which together need to perform with excellence the organizational climate

  3. Statistical Studies of Non-price Competition in the Structure of Public Procurement in the Russian Federation

    Directory of Open Access Journals (Sweden)

    Svetlana Aleksandrovna Sergeeva

    2016-04-01

    Full Text Available The principle of securing competition is one of the basic principles of the contract system in public procurement in the Russian Federation. The law on the contract system in procurement stipulates that the contract system in procurement is aimed at creating equal conditions to ensure competition between the parties to procurement. An important aspect is that the competition for procurement should be based on compliance with the principle of fair price and non-price competition. The purpose of this provision is to identify the best conditions for supplying goods, performing works and providing services. The analysis of the state of non-price competition in the procurement structure requires statistical studies of the phenomenon. The article considers the theoretical basis of non-price competition; it presents an analysis of methods of statistical study of non-price competition.

  4. Darwin's Arguments in Favour of Natural Selection and against Special Creationism

    Science.gov (United States)

    Nola, Robert

    2013-01-01

    In many places in "The Origin of Species", Darwin compares his own theory of Natural Selection favourably with Special Creationism which comes off as a bad second best. He does this using some version of the argument form known as "Inference to the Best Explanation". The first part of this paper is methodological. It considers Whewell's notion of…

  5. Does disturbance favour weak competitors? Mechanisms of changing plant abundance after flooding

    NARCIS (Netherlands)

    Lenssen, J.P.M.; Steeg, A. van der; Kroon, J.C.J.M. de

    2004-01-01

    Question: Does disturbance reduce competition intensity and thus favour weak competitors that are presumably less affected by disturbance than strong competitors? Methods: We used a single flooding event with increasing duration to simulate disturbance with increasing intensity. Six flood-plain gras

  6. Sequential use of human-derived medium supplements favours cardiovascular tissue engineering

    NARCIS (Netherlands)

    Vis, Paul W. Riem; Sluijter, Joost P. G.; Soekhradj-Soechit, R. Sarita; van Herwerden, Lex A.; Kluin, Jolanda; Bouten, Carlijn V. C.

    2012-01-01

    For clinical application of tissue engineering strategies, the use of animal-derived serum in culture medium is not recommended, because it can evoke immune responses in patients. We previously observed that human platelet-lysate (PL) is favourable for cell expansion, but generates weaker tissue as

  7. Sequential use of human-derived medium supplements favours cardiovascular tissue engineering

    NARCIS (Netherlands)

    Vis, Paul W. Riem; Sluijter, Joost P. G.; Soekhradj-Soechit, R. Sarita; van Herwerden, Lex A.; Kluin, Jolanda; Bouten, Carlijn V. C.

    2012-01-01

    For clinical application of tissue engineering strategies, the use of animal-derived serum in culture medium is not recommended, because it can evoke immune responses in patients. We previously observed that human platelet-lysate (PL) is favourable for cell expansion, but generates weaker tissue as

  8. Darwin's Arguments in Favour of Natural Selection and against Special Creationism

    Science.gov (United States)

    Nola, Robert

    2013-01-01

    In many places in "The Origin of Species", Darwin compares his own theory of Natural Selection favourably with Special Creationism which comes off as a bad second best. He does this using some version of the argument form known as "Inference to the Best Explanation". The first part of this paper is methodological. It considers Whewell's notion of…

  9. Trade policies and development of less-favoured areas: evidence from the literature

    NARCIS (Netherlands)

    Oskam, A.J.; Komen, M.H.C.; Wobst, P.; Yalew, A.

    2004-01-01

    The links between international markets and production and consumption decisions in less-favoured areas (LFAs) often appear rather loose. Hence, it may be questioned whether international trade and economic growth effects trickle down to LFAs. This paper explores the evidence in the literature in wh

  10. Crossing the Line: A Study of the Legal Permissibility of Using Federalized Troops to Protect the Nation’s Borders

    Science.gov (United States)

    2007-11-02

    bombing of the Oklahoma City Alfred P. Murrah Federal Building by an American terrorist. His proposal met stiff resistance on Capitol Hill from...attack was followed by the 1995 bombing of the Alfred P. Murrah Federal Building in Oklahoma City, Oklahoma. President Clinton, spurred on by these acts...federal court made decisions upholding the viability of limited military assistance to civilian law enforcement agencies. In United States v. Hitchcock

  11. Does the energy expenditure status in obstructive sleep apnea favour a positive energy balance?

    Science.gov (United States)

    Major, Geneviève C; Sériès, Frédéric; Tremblay, Angelo

    2007-01-01

    The effect of the obstructive sleep apnea syndrome on energy expenditure is controversial. The objective of this study was to assess the relationship between 24-hr energy expenditure or sleeping metabolic rate and features of the obstructive sleep apnea. Twenty-four apneic men took part in this cross-sectional study and were classified in quartiles of nocturnal desaturation severity, i.e. of percentage total sleep time with SaO2 hydrodensitometry. During the stay in the respiratory chamber, urine was collected to assess catecholamine concentration and percentage recording time with SaO2 < 90% (%TRT SaO2 < 90%) was measured with nocturnal oximetry. Mean fat free mass and fat mass were greater in quartile 4 than in quartile 1 (P < 0.05). %TRT SaO2 < 90% was higher in quartile 4 than in other quartiles (P < 0.0001). 24-hr energy expenditure and sleeping metabolic rate were similar among quartiles. However, when expressed on a per kg body weight basis (kcal/kg), these variables were negatively correlated with the %TRT SaO2 < 90% in the whole group (r = -0.46 and -0.48, respectively, P < 0.05). %TRT SaO2 < 90% was found to be a predictor of sleeping metabolic rate which explained, together with fat mass and fat free mass, 86% of this variance (P < 0.05). In apneic men energy expenditure relative to body weight decreases with increasing severity of oxygen desaturation which could favour a positive energy balance.

  12. After Halliburton: Event Studies and Their Role in Federal Securities Fraud Litigation

    NARCIS (Netherlands)

    J.E. Fisch (Jill); J.B. Gelbach (Jonah); J.M. Klick (Jonathan)

    2016-01-01

    markdownabstractEvent studies have become increasingly important in securities fraud litigation after the Supreme Court’s decision in Halliburton II. Litigants have used event study methodology, which empirically analyzes the relationship between the disclosure of corporate information and the issue

  13. The Balkanization of Nigeria's Federal System: A Case Study in the Political Geography of Africa

    Science.gov (United States)

    Rogge, John R.

    1977-01-01

    By means of a case study of Nigeria, this paper examines the issue of national unity and identity in the face of tribally based regionalism, diversity, and suspicion. Maps and tables accompany the article. (Author/AV)

  14. An Open-Source Strategy for Documenting Events: The Case Study of the 42nd Canadian Federal Election on Twitter

    Directory of Open Access Journals (Sweden)

    Nick Ruest

    2016-04-01

    Full Text Available This article examines the tools, approaches, collaboration, and findings of the Web Archives for Historical Research Group around the capture and analysis of about 4 million tweets during the 2015 Canadian Federal Election. We hope that national libraries and other heritage institutions will find our model useful as they consider how to capture, preserve, and analyze ongoing events using Twitter. While Twitter is not a representative sample of broader society - Pew research shows in their study of US users that it skews young, college-educated, and affluent (above $50,000 household income – Twitter still represents an exponential increase in the amount of information generated, retained, and preserved from 'everyday' people. Therefore, when historians study the 2015 federal election, Twitter will be a prime source.On August 3, 2015, the team initiated both a Search API and Stream API collection with twarc, a tool developed by Ed Summers, using the hashtag #elxn42. The hashtag referred to the election being Canada's 42nd general federal election (hence 'election 42' or elxn42. Data collection ceased on November 5, 2015, the day after Justin Trudeau was sworn in as the 42nd Prime Minister of Canada. We collected for a total of 102 days, 13 hours and 50 minutes. To analyze the data set, we took advantage of a number of command line tools, utilities that are available within twarc, twarc-report, and jq. In accordance with the Twitter Developer Agreement & Policy, and after ethical deliberations discussed below, we made the tweet IDs and other derivative data available in a data repository. This allows other people to use our dataset, cite our dataset, and enhance their own research projects by drawing on #elxn42 tweets. Our analytics included: breaking tweet text down by day to track change over time; client analysis, allowing us to see how the scale of mobile devices affected medium interactions; URL analysis, comparing both to Archive

  15. Vaccenic acid favourably alters immune function in obese JCR:LA-cp rats.

    Science.gov (United States)

    Blewett, Heather J; Gerdung, Christopher A; Ruth, Megan R; Proctor, Spencer D; Field, Catherine J

    2009-08-01

    Vaccenic acid (VA) is a ruminant-derived trans-fat and precursor of conjugated linoleic acid (CLA). The objective of the present study was to explore the effects of VA on immune function in a model of the metabolic syndrome, JCR:LA-cp rats. Lean (2:1 mix of +/cp and +/+) and obese (cp/cp) rats, aged 8 weeks, were fed a control (0% VA) or a VA diet (1.5% (w/w) VA) for 3 weeks (twenty rats per group). Splenocytes and mesenteric lymph node (MLN) immune cell phenotypes (flow cytometry), ex vivo cytokine production (ELISA) and phospholipid fatty acid concentrations were measured. Obese rats had higher proportions of splenic macrophages, total T-cells, helper T-cells (total and percentage CD25+), cytotoxic T-cells (total and percentage CD25+) and produced higher concentrations of IL-6 to concanavalin A (ConA) compared with lean rats. Obese rats had lower proportions of MLN T-cells, new T-cells (CD3+CD90+) and cytotoxic T-cells, but higher proportions of helper cells that were CD45RC+, CD25+ and CD4lo, and produced higher concentrations of IL-2, IL-10, interferon gamma and TNFalpha in response to ConA compared with lean rats. VA was higher in plasma phospholipids and both VA and CLA (cis-9, trans-11) were higher in MLN phospholipids compared with control-fed rats. Lean VA-fed rats had lower proportions of MLN and splenocyte CD45RC+ helper cells, and helper T-cells. Splenocytes from VA-fed rats produced 16-23% less IL-2, IL-10 and TNFalpha compared with controls. VA normalised production of MLN IL-2 and TNFalpha in obese rats to levels similar to those seen in lean rats. These results indicate that dietary VA favourably alters the pro-inflammatory tendency of mesenteric lymphocytes from JCR:LA-cp rats.

  16. Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population.

    Science.gov (United States)

    Oelmann, Simon; Nauck, Matthias; Völzke, Henry; Bahls, Martin; Friedrich, Nele

    2016-01-01

    Irisin is a myokine, which is mainly inversely associated with the risk for non-communicable diseases. Irisin improves cellular energy metabolism by uncoupling the mitochondrial respiratory chain resulting in increased energy expenditure using lipids. To date potential associations between irisin concentration and lipid profile are poorly understood. Therefore, this investigation aimed to evaluate potential associations between irisin and lipid levels in the general population. Data of 430 men and 537 women from the population-based Study of Health in Pomerania (SHIP-TREND) with available irisin and lipid concentrations were used. Analyses of variance, linear and logistic regression models adjusted for age, HBA1c, waist circumference, physical activity, smoking, alcohol consumption, systolic blood pressure, ALAT were calculated. We detected significantly inverse associations between irisin and circulating levels of total [beta coefficient 0.21 (standard error 0.08), p = 0.01], low-density cholesterol [-0.16 (0.07), p = 0.03] and triglycerides [-0.17 (0.08), p = 0.02] for men. Females without lipid lowering medication had an inverse association between irisin and total cholesterol [-0.12 (0.06), p = 0.05]. Further, male subjects with irisin concentrations in the third tertile had an increased odds for elevated low-density cholesterol [odds ratio 1.96 (95% confidence interval 1.07-3.48), p = 0.03) and triglyceride [1.95 (1.09-3.47), p = 0.02] levels, even after exclusion of subjects with lipid lowering medication. In addition, our data revealed an annual rhythm of serum irisin levels with peak levels arise in winter and summer months. This is the first investigation to report a significant association between circulating irisin and a favourable lipid profile in the general population. This may infer that higher irisin concentrations are associated with a reduced risk for non-communicable diseases.

  17. Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population.

    Directory of Open Access Journals (Sweden)

    Simon Oelmann

    Full Text Available Irisin is a myokine, which is mainly inversely associated with the risk for non-communicable diseases. Irisin improves cellular energy metabolism by uncoupling the mitochondrial respiratory chain resulting in increased energy expenditure using lipids. To date potential associations between irisin concentration and lipid profile are poorly understood. Therefore, this investigation aimed to evaluate potential associations between irisin and lipid levels in the general population.Data of 430 men and 537 women from the population-based Study of Health in Pomerania (SHIP-TREND with available irisin and lipid concentrations were used. Analyses of variance, linear and logistic regression models adjusted for age, HBA1c, waist circumference, physical activity, smoking, alcohol consumption, systolic blood pressure, ALAT were calculated.We detected significantly inverse associations between irisin and circulating levels of total [beta coefficient 0.21 (standard error 0.08, p = 0.01], low-density cholesterol [-0.16 (0.07, p = 0.03] and triglycerides [-0.17 (0.08, p = 0.02] for men. Females without lipid lowering medication had an inverse association between irisin and total cholesterol [-0.12 (0.06, p = 0.05]. Further, male subjects with irisin concentrations in the third tertile had an increased odds for elevated low-density cholesterol [odds ratio 1.96 (95% confidence interval 1.07-3.48, p = 0.03 and triglyceride [1.95 (1.09-3.47, p = 0.02] levels, even after exclusion of subjects with lipid lowering medication. In addition, our data revealed an annual rhythm of serum irisin levels with peak levels arise in winter and summer months.This is the first investigation to report a significant association between circulating irisin and a favourable lipid profile in the general population. This may infer that higher irisin concentrations are associated with a reduced risk for non-communicable diseases.

  18. Circadian rhythm of a Silene species favours nocturnal pollination and constrains diurnal visitation.

    Science.gov (United States)

    Prieto-Benítez, Samuel; Dötterl, Stefan; Giménez-Benavides, Luis

    2016-07-24

    Traits related to flower advertisement and reward sometimes vary in a circadian way, reflecting phenotypic specialization. However, specialized flowers are not necessarily restricted to specialized pollinators. This is the case of most Silene species, typically associated with diurnal or nocturnal syndromes of pollination but usually showing complex suites of pollinators. A Silene species with mixed floral features between diurnal and nocturnal syndromes was used to test how petal opening, nectar production, scent emission and pollination success correlate in a circadian rhythm, and whether this is influenced by environmental conditions. The effect of diurnal and nocturnal visitation rates on plant reproductive success is also explored in three populations, including the effect of the pollinating seed predator Hadena sancta KEY RESULTS: The result showed that repeated petal opening at dusk was correlated with nectar secretion and higher scent production during the night. However, depending on environmental conditions, petals remain opened for a while in the morning, when nectar and pollen still were available. Pollen deposition was similarly effective at night and in the morning, but less effective in the afternoon. These results were consistent with field studies. The circadian rhythm regulating floral attractiveness and reward in S. colorata is predominantly adapted to nocturnal flower visitors. However, favourable environmental conditions lengthen the optimal daily period of flower attraction and pollination towards morning. This allows the complementarity of day and night pollination. Diurnal pollination may help to compensate the plant reproductive success when nocturnal pollinators are scarce and when the net outcome of H. sancta shifts from mutualism to parasitism. These results suggest a functional mechanism explaining why the supposed nocturnal syndrome of many Silene species does not successfully predict their pollinator guilds. © The Author 2016

  19. A Study of Four Federal Graduate Fellowship Programs: Education and Employment Outcomes

    Science.gov (United States)

    Kraus, Lewis E.; Henke, Robin R.; Nevill, Stephanie; Linnard, David; Pflueger, Jeff; Mattox, Tiffany

    2008-01-01

    The Office of Postsecondary Education (OPE) in the U.S. Department of Education (ED) sponsors four graduate fellowship programs: the Fulbright-Hays Doctoral Dissertation Research Abroad (DDRA) fellowship program, the Foreign Language and Area Studies (FLAS) fellowship program, the Graduate Assistance in Areas of National Need (GAANN) fellowship …

  20. Data harmonization and federated analysis of population-based studies : the BioSHaRE project

    NARCIS (Netherlands)

    Doiron, Dany; Burton, Paul; Marcon, Yannick; Gaye, Amadou; Wolffenbuttel, Bruce H R; Perola, Markus; Stolk, Ronald P; Foco, Luisa; Minelli, Cosetta; Waldenberger, Melanie; Holle, Rolf; Kvaløy, Kirsti; Hillege, Hans L; Tassé, Anne-Marie; Ferretti, Vincent; Fortier, Isabel

    2013-01-01

    ABSTRACTS BACKGROUND: Individual-level data pooling of large population-based studies across research centres in international research projects faces many hurdles. The BioSHaRE (Biobank Standardisation and Harmonisation for Research Excellence in the European Union) project aims to address these is

  1. Data harmonization and federated analysis of population-based studies : the BioSHaRE project

    NARCIS (Netherlands)

    Doiron, Dany; Burton, Paul; Marcon, Yannick; Gaye, Amadou; Wolffenbuttel, Bruce H R; Perola, Markus; Stolk, Ronald P; Foco, Luisa; Minelli, Cosetta; Waldenberger, Melanie; Holle, Rolf; Kvaløy, Kirsti; Hillege, Hans L; Tassé, Anne-Marie; Ferretti, Vincent; Fortier, Isabel

    2013-01-01

    ABSTRACTS BACKGROUND: Individual-level data pooling of large population-based studies across research centres in international research projects faces many hurdles. The BioSHaRE (Biobank Standardisation and Harmonisation for Research Excellence in the European Union) project aims to address these

  2. Government-to-Government E-Government: A Case Study of a Federal Financial Program

    Science.gov (United States)

    Faokunla, Olumide Adegboyega

    2012-01-01

    The problem with the study of the concept of electronic government (e-Gov) is that scholars in the field have not adequately explored various dimensions of the concept. Literature on e-Gov is replete with works on the form of government to consumer e-Gov. Much less work had been done on the government to government (G2G) e-Gov. This qualitative…

  3. Fiscal Federalism

    Directory of Open Access Journals (Sweden)

    Tatiana Mosteanu

    2007-06-01

    Full Text Available The central budget of a country collects only a fraction of the total fiscal revenues and executes only o fraction of the national public expenditures, the rest of the revenues and expenditures becoming the responsability of subnational governments. The economist Charles Tiebout developed a theoretical model which although makes an imperfect description of the reality, shows that people’s mobility is being influenced by tax rates and the amount of state/local expenditures. Thus, he suggests that the degree of responsibility that can be appointed to the local budgets should subscribe to the tax – benefits ratio, the extend of the positive externalities and the scale economies of public goods. Also, the issue of revenues distribution among communities is being raised, being identified three kinds of grants used by the public authorities: matching grants, block grants and conditional block grants. In the concept of fiscal federalism there can be found a limited analogy between national public finance theory and international public finance theory, with the international taxation as the pivotal element.

  4. Data and Primary Source Documents for Social Studies Classrooms from the Federal Reserve Bank of St. Louis

    Science.gov (United States)

    Suiter, Mary C.; Stierholz, Katrina L.

    2011-01-01

    Data and primary source documents are important for understanding past and current events. The Federal Reserve Bank of St. Louis has committed itself to the collection and illumination of economic data and historical information for classroom teachers and researchers. The Federal Reserve Bank of St. Louis provides a number of services--including…

  5. Herbs of interest to the Brazilian Federal Government: female reproductive and developmental toxicity studies

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Verissimo

    2011-12-01

    Full Text Available In 2009 the Brazilian Ministry of Health published a document named RENISUS that lists 71 herbs traditionally used in Brazil that could result in phytomedicines to be dispensed by the governmental health care program. This manuscript reviews female reproductive and/or developmental toxicity information of these herbs. More than half (35 of the herbs lack information regarding female reproductive and/or developmental effects. From the fourteen herbs used traditionally to disturb female reproduction, five present experimental data corroborating their actions as abortifacients (Maytenus ilicifolia, Momordica charantia, Plectranthus barbatus, Ruta graveolens or labour facilitator (Bidens pilosa. For 23 of the herbs evaluated experimentally for any type of female reproductive endpoint, only a single study was retrieved and at least twelve of these studies were conducted with a single dose. This scenario suggests that the scientific power of the published information is very low and that a scientifically-based risk/benefit analysis about the use of these herbs during pregnancy is not possible. Considering the appeal that phytomedicines have for pregnant women, usually aware and afraid of the risks that synthetic drugs may have in their pregnancy and progeny, well designed studies evaluating reproductive and/or developmental toxicity of these herbs urge.

  6. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for NASA Glenn Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Schey, Stephen [Idaho National Lab. (INL), Idaho Falls, ID (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-10-01

    The Advanced Vehicle Testing Activity’s study seeks to collect and evaluate data to validate the utilization of advanced plug-in electric vehicle (PEV) transportation. This report focuses on the NASA Glenn Research Center (GRC) fleet to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of PEVs into the agencies’ fleets. Individual observations of these selected vehicles provide the basis for recommendations related to electric vehicle adoption and whether a battery electric vehicle or plug-in hybrid electric vehicle (collectively referred to as PEVs) can fulfill the mission requirements.

  7. A STUDY OF THE DISCREPANCY BETWEEN FEDERAL AND STATE MEASUREMENTS OF ON-HIGHWAY FUEL CONSUMPTION

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, HL

    2003-08-11

    Annual highway fuel taxes are collected by the Treasury Department and placed in the Highway Trust Fund (HTF). There is, however, no direct connection between the taxes collected by the Treasury Department and the gallons of on-highway fuel use, which can lead to a discrepancy between these totals. This study was conducted to determine how much of a discrepancy exists between the total fuel usages estimated based on highway revenue funds as reported by the Treasury Department and the total fuel usages used in the apportionment of the HTF to the States. The analysis was conducted using data from Highway Statistics Tables MF-27 and FE-9 for the years 1991-2001. It was found that the overall discrepancy is relatively small, mostly within 5% difference. The amount of the discrepancy varies from year to year and varies among the three fuel types (gasoline, gasohol, special fuels). Several potential explanations for these discrepancies were identified, including issues on data, tax measurement, gallon measurement, HTF receipts, and timing. Data anomalies caused by outside forces, such as deferment of tax payments from one fiscal year to the next, can skew fuel tax data. Fuel tax evasion can lead to differences between actual fuel use and fuel taxes collected. Furthermore, differences in data collection and reporting among States can impact fuel use data. Refunds, credits, and transfers from the HTF can impact the total fuel tax receipt data. Timing issues, such as calendar year vs. fiscal year, can also cause some discrepancy between the two data sources.

  8. Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males

    OpenAIRE

    Lovlie, H.; Gillingham, M. A. F.; WORLEY K; Pizzari, T.; Richardson, David

    2013-01-01

    Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus gallus, bias sperm use in favour of unrelated males. Here, we experimentally investigate whether this bias is driven by relatedness per se, or by similarity at the major histocompatibility complex (MHC), genes central to vertebrate acquired i...

  9. Subungual Squamous Cell Carcinoma Associated with Long Standing Onychomycosis: Aggressive Surgical Approach with a Favourable Outcome

    Directory of Open Access Journals (Sweden)

    Yavor Grigorov

    2017-07-01

    CONCLUSION: Although there are no available data in the literature to confirm or reject the contribution of the chronic nail infection to the malignant process, we emphasise the importance of this co-existence regarding the possible disguising of the malignant process. An early biopsy of a chronic persistent nail lesion may be preventive and beneficial regarding avoiding more aggressive treatments and achieving a favourable prognosis.

  10. Identifying the Environmental Conditions Favouring West Nile Virus Outbreaks in Europe

    OpenAIRE

    Marcantonio, Matteo; Rizzoli, Annapaola; Metz, Markus; Rosà, Roberto; Marini, Giovanni; Chadwick, Elizabeth Anna; Neteler, Markus

    2015-01-01

    West Nile Virus (WNV) is a globally important mosquito borne virus, with significant implications for human and animal health. The emergence and spread of new lineages, and increased pathogenicity, is the cause of escalating public health concern. Pinpointing the environmental conditions that favour WNV circulation and transmission to humans is challenging, due both to the complexity of its biological cycle, and the under-diagnosis and reporting of epidemiological data. Here, we used remote s...

  11. 43 CFR 404.35 - Is there a different non-Federal cost-share requirement for feasibility studies that involve a...

    Science.gov (United States)

    2010-10-01

    ...-share requirement for feasibility studies that involve a community greater than 50,000 inhabitants? 404... non-Federal cost-share requirement for feasibility studies that involve a community greater than 50,000 inhabitants? Yes. If the feasibility study involves a rural water supply system that will serve...

  12. The accident at Gorleben: A case study of risk communication and risk amplification in the Federal Republic of Germany

    Energy Technology Data Exchange (ETDEWEB)

    Peters, H P; Hennen, L [Clark Univ., Worcester, MA (USA). Center for Technology, Environment, and Development

    1988-07-01

    On May 12, 1987 an accident happened in the ``pilot mine`` at Gorleben in the Federal Republic of Germany where the feasibility of a repository or high-radioactive nuclear waste is currently being investigated. A miner was killed during that accident and two others were severely injured. Although this accident happened during conventional mining work and had nothing to do with radioactive waste, this event received much public attention and news coverage and had a strong impact on the political debate on the Gorleben project of a repository mine for radioactive waste and even on the nuclear power controversy in general. This study does not aim to evaluate the accident that happened in the Gorleben pilot mine from a geological point of view nor does it aim to evaluate the West German waste disposal concept. All information given in chapter 2 on these aspects should be considered as background information, useful in understanding the subject of this case study: the risk communication concerning the Gorleben project in general and the accident in the shaft in particular.

  13. Iodine Intake through Processed Food: Case Studies from Egypt, Indonesia, the Philippines, the Russian Federation and Ukraine, 2010–2015

    Directory of Open Access Journals (Sweden)

    Jacky Knowles

    2017-07-01

    Full Text Available The current performance indicator for universal salt iodisation (USI is the percentage of households using adequately iodised salt. However, the proportion of dietary salt from household salt is decreasing with the increase in consumption of processed foods and condiments globally. This paper reports on case studies supported by the Global Alliance for Improved Nutrition (GAIN-UNICEF USI Partnership Project to investigate processed food industry use of adequately iodised salt in contrasting national contexts. Studies were conducted in Egypt, Indonesia, the Philippines, the Russian Federation, and Ukraine. In all cases, the potential iodine intake from iodised salt in selected food products was modelled according to the formula: quantity of salt per unit of food product × minimum regulated iodine level of salt at production × average daily per capita consumption of the product. The percent of adult recommended nutrient intake for iodine potentially provided by the average daily intake of bread and frequently consumed foods and condiments was from 10% to 80% at the individual product level. The potential contribution to iodine intake from the use of iodised salt in the processed food industry is of growing significance. National USI strategies should encourage co-operative industry engagement and include regulatory monitoring of iodised salt use in the food industry in order to achieve optimal population iodine status.

  14. Argonne National Laboratory study of the transfer of federal computational technology to manufacturing industry in the State of Michigan

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, C.J.

    1991-11-01

    This report describes a pilot study to develop, initiate the implementation, and document a process to identify computational technology capabilities resident within Argonne National Laboratory to small and medium-sized businesses in the State of Michigan. It is a derivative of a program entitled ``Technology Applications Development Process for the State of Michigan`` undertaken by the Industrial Technology Institute and MERRA under funding from the National Institute of Standards and Technology. The overall objective of the latter program is to develop procedures which can facilitate the discovery and commercialization of new technologies for the benefit of small and medium-size manufacturing firms. Federal laboratories such as Argonne, along with universities, have been identified by the Industrial Technology Institute as key sources of technology which can be profitably commercialized by the target firms. The scope of this study limited the investigation of technology areas for technology transfer to that of computational science and engineering featuring high performance computing. This area was chosen as the broad technological capability within Argonne to investigate for technology transfer to Michigan firms for several reasons. First, and most importantly, as a multidisciplinary laboratory, Argonne has the full range of scientific and engineering skills needed to utilize leading-edge computing capabilities in many areas of manufacturing.

  15. Argonne National Laboratory study of the transfer of federal computational technology to manufacturing industry in the State of Michigan

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, C.J.

    1991-11-01

    This report describes a pilot study to develop, initiate the implementation, and document a process to identify computational technology capabilities resident within Argonne National Laboratory to small and medium-sized businesses in the State of Michigan. It is a derivative of a program entitled Technology Applications Development Process for the State of Michigan'' undertaken by the Industrial Technology Institute and MERRA under funding from the National Institute of Standards and Technology. The overall objective of the latter program is to develop procedures which can facilitate the discovery and commercialization of new technologies for the benefit of small and medium-size manufacturing firms. Federal laboratories such as Argonne, along with universities, have been identified by the Industrial Technology Institute as key sources of technology which can be profitably commercialized by the target firms. The scope of this study limited the investigation of technology areas for technology transfer to that of computational science and engineering featuring high performance computing. This area was chosen as the broad technological capability within Argonne to investigate for technology transfer to Michigan firms for several reasons. First, and most importantly, as a multidisciplinary laboratory, Argonne has the full range of scientific and engineering skills needed to utilize leading-edge computing capabilities in many areas of manufacturing.

  16. Financial Impact of Energy Efficiency under a Federal Renewable Electricity Standard: Case Study of a Kansas"super-utility"

    Energy Technology Data Exchange (ETDEWEB)

    Goldman, Charles A.; Cappers, Peter

    2009-12-01

    Local, state and federal policies that jointly promote the generation of electricity from renewable technologies and the pursuit of energy efficiency are expected to help mitigate the detrimental effects of global climate change and foster energy independence. We examine the financial impacts on various stakeholders from alternative compliance strategies with a Combined Efficiency and Renewable Electricity Standard (CERES) using a case study approach for utilities in Kansas. If only supply-side options are considered, our analysis suggests that a Kansas"super-utility" would prefer to build its own renewable energy resources, while ratepayers would favor a procurement strategy that relies on long-term renewable power purchase agreements. Introducing energy efficiency under varying levels as a CERES resource will, under our analysis, reduce ratepayer bills by ~;;$400M to ~;;$1.0B between 2009 and 2028, but commensurately erode shareholder returns by ~;;10 to ~;;100 basis points. If a business model for energy efficiency inclusive of both a lost fixed cost recovery mechanism and a shareholder incentive mechanism is implemented, our results illustrate how shareholder returns can be improved through the pursuit of energy efficiency, by at most ~;;20 basis points if certain conditions apply, while ratepayers continue to save between $10M and ~;;$840M over 20 years.

  17. Contribution of Integrated Management Systems to University Management: Case Study of the Federal University of Rio Grande Do Norte

    Directory of Open Access Journals (Sweden)

    Lucas A.B.D Oliveira

    2011-01-01

    Full Text Available Problem statement: The Higher Education Institutions (IHL have intensified process of introducing undergraduate and graduate courses to more remote regions, which expanded the scope of what these institutions and allowed the formation of population of these regions. This expansion (whether by on-campus or distance learning presents new challenges for university management and integration of the players involved in this process. The purpose of this article was to demonstrate importance of information systems for university management and integration, focusing on decentralization and expansion of IHsL. Approach: The investigation was descriptive and the article is practical in nature. A case study was conducted at the Federal University of Rio Grande do Norte (Brazil. The research proposal of article was to answer the following question: How does an information system contribute to managing university expansion? Results: Results showed the relevance of integrated management systems, given university expansion and broadened horizons observed in recent years. The system analyzed proved to be extremely efficient, since practically all university activities can be monitored and evaluated. Conclusion: It was concluded that using integrated management systems during higher learning expansion maximizes this process, resulting in credible and rapid procedures that are more efficient and more effective.

  18. Study of the cerrado vegetation in the Federal District area from orbital data. M.S. Thesis

    Science.gov (United States)

    Dejesusparada, N. (Principal Investigator); Aoki, H.; Dossantos, J. R.

    1980-01-01

    The physiognomic units of cerrado in the area of Distrito Federal (DF) were studied through the visual and automatic analysis of products provided by Multispectral Scanning System (MSS) of LANDSAT. The visual analysis of the multispectral images in black and white, at the 1:250,000 scale, was made based on the texture and tonal patterns. The automatic analysis of the compatible computer tapes (CCT) was made by means of IMAGE-100 system. The following conclusions were obtained: (1) the delimitation of cerrado vegetation forms can be made by the visual and automatic analysis; (2) in the visual analysis, the principal parameter used to discriminate the cerrado forms was the tonal pattern, independently of the year's seasons, and the channel 5 gave better information; (3) in the automatic analysis, the data of the four channels of MSS can be used in the discrimination of the cerrado forms; and (4) in the automatic analysis, the four channels combination possibilities gave more information in the separation of cerrado units when soil types were considered.

  19. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for the National Park Service: Fort Vancouver National Historic Site

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Schey; Jim Francfort

    2014-03-01

    Battelle Energy Alliance, LLC, managing and operating contractor for the U.S. Department of Energy’s Idaho National Laboratory, is the lead laboratory for the U.S. Department of Energy’s Advanced Vehicle Testing. Battelle Energy Alliance, LLC contracted with Intertek Testing Services, North America (ITSNA) to collect data on federal fleet operations as part of the Advanced Vehicle Testing Activity’s Federal Fleet Vehicle Data Logging and Characterization study. The Advanced Vehicle Testing Activity study seeks to collect data to validate the use of advanced electric drive vehicle transportation. This report focuses on the Fort Vancouver National Historic Site (FVNHS) fleet to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of electric vehicles (EVs) into the agencies’ fleet. Individual observations of the selected vehicles provided the basis for recommendations related to EV adoption and whether a battery electric vehicle (BEV) or plug-in hybrid electric vehicle (PHEV) (collectively plug-in electric vehicles) could fulfill the mission requirements. FVNHS identified three vehicles in its fleet for consideration. While the FVNHS vehicles conduct many different missions, only two (i.e., support and pool missions) were selected by agency management to be part of this fleet evaluation. The logged vehicles included a pickup truck and a minivan. This report will show that BEVs and PHEVs are capable of performing the required missions and providing an alternative vehicle for both mission categories, because each has sufficient range for individual trips and time available each day for charging to accommodate multiple trips per day. These charging events could occur at the vehicle’s home base, high-use work areas, or in intermediate areas along routes that the vehicles frequently travel. Replacement of vehicles in the current fleet would result in

  20. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for the National Park Service: Golden Gate National Recreation Area

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Schey; Jim Francfort

    2014-03-01

    Battelle Energy Alliance, LLC, managing and operating contractor for the U.S. Department of Energy's Idaho National Laboratory, is the lead laboratory for U.S. Department of Energy Advanced Vehicle Testing. Battelle Energy Alliance, LLC contracted with Intertek Testing Services, North America (ITSNA) to collect data on federal fleet operations as part of the Advanced Vehicle Testing Activity's Federal Fleet Vehicle Data Logging and Characterization study. The Advanced Vehicle Testing Activity study seeks to collect data to validate the utilization of advanced electric drive vehicle transportation. This report focuses on the Golden Gate National Recreation Area (GGNRA) fleet to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of plug-in electric vehicles (PEVs) into the agencies' fleets. Individual observations of these selected vehicles provide the basis for recommendations related to electric vehicle adoption and whether a battery electric vehicle or plug-in hybrid electric vehicle (PHEV) (collectively PEVs) can fulfill the mission requirements. GGNRA identified 182 vehicles in its fleet, which are under the management of the U.S. General Services Administration. Fleet vehicle mission categories are defined in Section 4, and while the GGNRA vehicles conduct many different missions, only two (i.e., support and law enforcement missions) were selected by agency management to be part of this fleet evaluation. The selected vehicles included sedans, trucks, and sport-utility vehicles. This report will show that battery electric vehicles and/or PHEVs are capable of performing the required missions and providing an alternative vehicle for support vehicles and PHEVs provide the same for law enforcement, because each has a sufficient range for individual trips and time is available each day for charging to accommodate multiple trips per day. These

  1. Marketing, Information, and Parental Choice: A Comparative Case Study of Third-Party, Federally Funded Out-of-School-Time Services

    Science.gov (United States)

    Stewart, Molly S.; Good, Annalee G.

    2016-01-01

    Information and promotional marketing play central but complex roles in market-based educational programs. This in-depth qualitative study examines these complexities using the case of Supplemental Educational Services, a parental choice program providing federally funded tutoring to low-income students in K-12 public schools. Examining the…

  2. Does Working Help or Hurt College Students? The Effects of Federal Work-Study Participation on Student Outcomes. A CAPSEE Working Paper

    Science.gov (United States)

    Soliz, Adela; Long, Bridget Terry

    2016-01-01

    Due to rising costs and declining affordability, many students have to work while attending college. The federal government takes a major role in subsidizing the wages of college students and spent over $1 billion on the Work-Study program in 2010-11 (College Board, 2011), yet little is known about how working during the school year impacts…

  3. Marketing, Information, and Parental Choice: A Comparative Case Study of Third-Party, Federally Funded Out-of-School-Time Services

    Science.gov (United States)

    Stewart, Molly S.; Good, Annalee G.

    2016-01-01

    Information and promotional marketing play central but complex roles in market-based educational programs. This in-depth qualitative study examines these complexities using the case of Supplemental Educational Services, a parental choice program providing federally funded tutoring to low-income students in K-12 public schools. Examining the…

  4. Union-Active School Librarians and School Library Advocacy: A Modified Case Study of the British Columbia Teacher-Librarians' Association and the British Columbia Teachers' Federation

    Science.gov (United States)

    Ewbank, Ann Dutton

    2015-01-01

    This modified case study examines how the members of the British Columbia Teacher-Librarians' Association (BCTLA), a Provincial Specialist Association (PSA) of the British Columbia Teachers' Federation (BCTF), work together to advocate for strong school library programs headed by a credentialed school librarian. Since 2002, despite nullification…

  5. Occupational and Qualification Structures in the Field of Environmental Protection in the Metal and Chemical Industries--Study on the Federal Republic of Germany.

    Science.gov (United States)

    Nitschke, Christoph; And Others

    A study focused on new occupational and qualification structures in the field of environmental protection in the metal and chemical industries in the Federal Republic of Germany. A total of 22 interviews were conducted with representatives of 11 firms. The public debate on occupational requirements in the field of environmental protection and on…

  6. Time until first dental caries for young children first seen in Federally Qualified Health Centers: a retrospective cohort study

    Science.gov (United States)

    Kuthy, RA; Jones, M; Kavand, G; Momany, E; Askelson, N; Chi, D; Wehby, G; Damiano, P

    2014-01-01

    Objective The study assessed the time until first dental caries for young children seen at 5 Federally Qualified Health Centers (FQHC) in Iowa and the relationship with the frequency and gaps (in months) of dental episodes, the number of topical fluoride treatments, and the number of dentists caring for the subject. Methods Forty children were randomly selected at each FQHC (n=200). All children were continuously enrolled in the Medicaid program and had their first dental visit prior to age 6. Dental chart findings, claims data for the child and family, and birth certificate information were merged into one dataset. Dental visits were followed for a minimum of 36 months, including dental visits external to the FQHCs. Using time until first caries as the dependent variable, the data were subject to left, interval, and right censoring and were analyzed via Weibull regression. Results Slightly more than half of the 200 children experienced caries. Regression analysis indicated that the hazard rate of first dental caries increased by approximately 2% with each additional month that transpired between preventive recall examinations. In addition, children with older siblings who had a dental visit at the same center during the previous year prior to the subject’s first visit were more likely to have a longer time until first dental caries. Conclusions Timing of dental care episodes was associated with caries experience in young children from low income families. Dental professionals should focus on regularity of dental care in order to prevent or delay caries experience in young children. PMID:24483730

  7. Women favour dyadic relationships, but men prefer clubs: cross-cultural evidence from social networking.

    Directory of Open Access Journals (Sweden)

    Tamas David-Barrett

    Full Text Available The ability to create lasting, trust-based friendships makes it possible for humans to form large and coherent groups. The recent literature on the evolution of sociality and on the network dynamics of human societies suggests that large human groups have a layered structure generated by emotionally supported social relationships. There are also gender differences in adult social style which may involve different trade-offs between the quantity and quality of friendships. Although many have suggested that females tend to focus on intimate relations with a few other females, while males build larger, more hierarchical coalitions, the existence of such gender differences is disputed and data from adults is scarce. Here, we present cross-cultural evidence for gender differences in the preference for close friendships. We use a sample of ∼112,000 profile pictures from nine world regions posted on a popular social networking site to show that, in self-selected displays of social relationships, women favour dyadic relations, whereas men favour larger, all-male cliques. These apparently different solutions to quality-quantity trade-offs suggest a universal and fundamental difference in the function of close friendships for the two sexes.

  8. Women favour dyadic relationships, but men prefer clubs: cross-cultural evidence from social networking.

    Science.gov (United States)

    David-Barrett, Tamas; Rotkirch, Anna; Carney, James; Behncke Izquierdo, Isabel; Krems, Jaimie A; Townley, Dylan; McDaniell, Elinor; Byrne-Smith, Anna; Dunbar, Robin I M

    2015-01-01

    The ability to create lasting, trust-based friendships makes it possible for humans to form large and coherent groups. The recent literature on the evolution of sociality and on the network dynamics of human societies suggests that large human groups have a layered structure generated by emotionally supported social relationships. There are also gender differences in adult social style which may involve different trade-offs between the quantity and quality of friendships. Although many have suggested that females tend to focus on intimate relations with a few other females, while males build larger, more hierarchical coalitions, the existence of such gender differences is disputed and data from adults is scarce. Here, we present cross-cultural evidence for gender differences in the preference for close friendships. We use a sample of ∼112,000 profile pictures from nine world regions posted on a popular social networking site to show that, in self-selected displays of social relationships, women favour dyadic relations, whereas men favour larger, all-male cliques. These apparently different solutions to quality-quantity trade-offs suggest a universal and fundamental difference in the function of close friendships for the two sexes.

  9. SIMPROVING THE ECONOMIC ACTIVITIES IN THE LESS FAVOURED AREAS OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Tileaga Cosmin

    2011-07-01

    Full Text Available This paper deals with finding solutions for improving the economic activities in Romania’s undeveloped areas, which still represent a major problem for this country’s economy. During 1999 and 2009, these areas were considered tax havens, due to some facilities accorded by the Government and the EU (headage compensatory allowances*, tax deductions, non-refundable funds. Many had the opportunity to invest in those regions, but no positive effect was to be seen. Tulcea County (Danube Delta area, coal mine regions, rural areas and the North-East area (Suceava and Botosani county are considered to be Romania’s less favoured areas. * The objective of these schemes is to provide a reasonable level of income for farmers where natural production conditions are least favourable so as to conserve the countryside by the prevention of further depopulation of rural areas. Compensatory allowances are payable to farmers for the keeping of cattle, sheep and goats. (www.europa.eu

  10. Alterations in energy homeostasis to favour adipose tissue gain: A longitudinal study in healthy pregnant women.

    Science.gov (United States)

    Abeysekera, Minoli V; Morris, Jack A; Davis, Gregory K; O'Sullivan, Anthony J

    2016-02-01

    Pregnancy is associated with an increase in body fat; however, excessive gestational weight gain predisposes to significant maternal and neonatal morbidity and mortality. It remains unclear whether alterations in energy homeostasis have a major influence on fat storage. To evaluate longitudinal changes in body composition and energy metabolism in healthy pregnant women. Body composition, energy expenditure and energy intake were measured longitudinally in 26 women with singleton pregnancies at 12-14 weeks, 24-26 weeks and 34-36 weeks of gestation. Fat mass (FM) and lean body mass (LBM) were measured using bio-impedance analysis, total energy expenditure (TEE) using the Sensewear Armband and energy intake through a 3-day food recall diary. Throughout pregnancy, all women remained healthy. Body weight increased by 10.8 ± 3.9 kg, from 67.3 ± 14.1 kg to 78.1 ± 13.8 kg from the first to the third trimester (P Body fat percentage increased by 4.5 ± 4.2% (P change significantly throughout pregnancy. Healthy women increase FM during pregnancy despite slight increases in TEE and no change in energy intake. This suggests that energy storage efficiency improves during pregnancy, which may be related to alterations in gut microbiota and activation of anabolic pathways during pregnancy. Clarifying factors leading to this more efficient fat and energy storing state, and the role of the pregnancy-related changes in gut microbiota, may be important for managing gestational weight gain. © 2015 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  11. Provider beliefs associated with cervical cancer screening interval recommendations: A pilot study in Federally Qualified Health Centers

    Directory of Open Access Journals (Sweden)

    Katherine B. Roland

    2015-01-01

    Conclusion: Messages that promote the benefits of longer screening intervals after a normal co-test, the natural history of human papillomavirus and cervical cancer, and low risk of developing cancer with a longer interval may be useful to promote evidence-based screening in this population of Federally Qualified Health Center providers. Dissemination of targeted messages through professional journals and specialty organizations should be considered.

  12. Soft Gamma-ray selected radio galaxies: favouring giant size discovery

    Science.gov (United States)

    Panessa, Francesca; Bassani, Loredana

    2016-07-01

    Using the recent INTEGRAL/IBIS and Swift/BAT surveys we have extracted a sample of radio galaxies selected in the soft gamma-ray band. The sample consists of known and candidate radio galaxies. The sample extraction criteria will be presented and its general properties outlined. In particular we provide strong evidence that this soft gamma-ray selection favours the discovery of large size radio objects, otherwise known as Giant Radio Galaxies or GRG. The main reasons and/or conditions leading to the formation of these sources are still unclear and this result suggests that they maybe related to exceptional internal properties of the source central engine, like a high jet power or a long activity time. Broad band analysis of new GRG, discovered during this work, will also be presented.

  13. Training information service specialists in the less favoured regions of the European Union (TRAIN-ISS

    Directory of Open Access Journals (Sweden)

    I. Owens

    1996-01-01

    Full Text Available The expanding information infrastructure in Europe will increase the demand for high-quality, easily accessible and usable information services. At the same time, in the Information Society, there will be an increasing demand for professionals with skills, able to improve their potential through life long learning, accessing and using information sources available world-wide. Highly qualified information professionals are a crucial asset in any society to enable it to reap all the benefits and opportunities created by the Information Market. In the Less Favoured Regions (LFRs of the European Union there is a shortage of education and training opportunities for information professionals to enable them to cope with the rapidly changing environment. It was to address this need for well qualified and trained information professionals that the TRAIN-ISS project was funded under the IMPACT 2 programme of the Commission of the European Communities

  14. An appeal to humanity: legal victory in favour of North America's only supervised injection facility: Insite.

    Science.gov (United States)

    Small, Dan

    2010-10-09

    Canada's federal government has once again failed to shut North America's only authorized supervised injection facility: Insite. A majority ruling issued by the BC Court of Appeal on 15 January 2010 upheld an earlier British Columbia Supreme Court ruling in 2008 that protected the rights of injection drug users (IDUs) to access Insite as a health facility as per the Charter of Rights and Freedoms component of the Constitution of Canada. The majority decision from Honourable Madam Justices Rowles, Huddart and Smith also established a jurisdictional victory safeguarding Insite as most appropriately run under the authority of the province of British Columbia rather than the federal Government of Canada. The Federal Government has appealed the case to the Supreme Court of Canada. A hearing date has been set for 12 May 2011. The appeal will be a legal one but even more so, it will be an appeal to humanity.

  15. An appeal to humanity: legal victory in favour of North America's only supervised injection facility: Insite

    Directory of Open Access Journals (Sweden)

    Small Dan

    2010-10-01

    Full Text Available Abstract Canada's federal government has once again failed to shut North America's only authorized supervised injection facility: Insite. A majority ruling issued by the BC Court of Appeal on 15 January 2010 upheld an earlier British Columbia Supreme Court ruling in 2008 that protected the rights of injection drug users (IDUs to access Insite as a health facility as per the Charter of Rights and Freedoms component of the Constitution of Canada. The majority decision from Honourable Madam Justices Rowles, Huddart and Smith also established a jurisdictional victory safeguarding Insite as most appropriately run under the authority of the province of British Columbia rather than the federal Government of Canada. The Federal Government has appealed the case to the Supreme Court of Canada. A hearing date has been set for 12 May 2011. The appeal will be a legal one but even more so, it will be an appeal to humanity.

  16. Autistic regression with and without EEG abnormalities followed by favourable outcome.

    Science.gov (United States)

    Zappella, Michele

    2010-10-01

    To explore the relationship between autistic regression (AR) with and without EEG abnormalities and favourable outcome. Follow up data on children with favourable outcome in a series of 534 cases aged below 5 years and diagnosed as ASD. Cases with regression were 167 (31.8%), usually with persistent ASD, intellectual disabilities and EEG abnormalities. Thirty nine children (7.3%) went off autism and recovered entirely their intellectual and social abilities. Few of them included examples of pharmacologically treated Landau and Kleffner syndrome and other similar complex cases with abnormal EEG. The majority was represented by 36 (6.7%) children, mostly males, with a dysmaturational syndrome: their development was initially normal up to 18 months when an autistic regression occurred accompanied by the appearance of motor and vocal tics. Relational therapies were followed by rapid improvement. By 6 years all children had lost features of ASD and their I.Q. was in most cases between 90 and 110. Convulsions were absent and EEG was normal in all cases except one. In a few of them recovery was spontaneous. Seventeen children were followed after 5 years 6 months: 12 (70%) had ADHD, 10 (56%) persistent tics. Tics were often present in parents and relatives, ASD absent, suggesting a genetic background different from cases with persistent ASD. With one exception all "off autism" children had a previous autistic regression. In this series "off autism" children had either early onset epilepsy and/or EEG abnormalities or cases of dysmaturational syndrome. Autistic regression was present in almost all. Copyright © 2010. Published by Elsevier B.V.

  17. Federal technology transfer requirements :a focused study of principal agencies approaches with implications for the Department of Homeland Security.

    Energy Technology Data Exchange (ETDEWEB)

    Koker, Denise; Micheau, Jill M.

    2006-07-01

    This report provides relevant information and analysis to the Department of Homeland Security (DHS) that will assist DHS in determining how to meet the requirements of federal technology transfer legislation. These legal requirements are grouped into five categories: (1) establishing an Office of Research and Technology Applications, or providing the functions thereof; (2) information management; (3) enabling agreements with non-federal partners; (4) royalty sharing; and (5) invention ownership/obligations. These five categories provide the organizing framework for this study, which benchmarks other federal agencies/laboratories engaged in technology transfer/transition Four key agencies--the Department of Health & Human Services (HHS), the U.S. Department of Agriculture (USDA), the Department of Energy (DOE), and the Department of Defense (DoD)--and several of their laboratories have been surveyed. An analysis of DHS's mission needs for commercializing R&D compared to those agencies/laboratories is presented with implications and next steps for DHS's consideration. Federal technology transfer legislation, requirements, and practices have evolved over the decades as agencies and laboratories have grown more knowledgeable and sophisticated in their efforts to conduct technology transfer and as needs and opinions in the federal sector have changed with regards to what is appropriate. The need to address requirements in a fairly thorough manner has, therefore, resulted in a lengthy paper. There are two ways to find summary information. Each chapter concludes with a summary, and there is an overall ''Summary and Next Steps'' chapter on pages 57-60. For those readers who are unable to read the entire document, we recommend referring to these pages.

  18. Federal laboratories for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Gover, J. [Sandia National Labs., Albuquerque, NM (United States); Huray, P.G. [Univ. of South Carolina, Columbia, SC (United States)

    1998-04-01

    Federal laboratories have successfully filled many roles for the public; however, as the 21st Century nears it is time to rethink and reevaluate how Federal laboratories can better support the public and identify new roles for this class of publicly-owned institutions. The productivity of the Federal laboratory system can be increased by making use of public outcome metrics, by benchmarking laboratories, by deploying innovative new governance models, by partnerships of Federal laboratories with universities and companies, and by accelerating the transition of federal laboratories and the agencies that own them into learning organizations. The authors must learn how government-owned laboratories in other countries serve their public. Taiwan`s government laboratory, Industrial Technology Research Institute, has been particularly successful in promoting economic growth. It is time to stop operating Federal laboratories as monopoly institutions; therefore, competition between Federal laboratories must be promoted. Additionally, Federal laboratories capable of addressing emerging 21st century public problems must be identified and given the challenge of serving the public in innovative new ways. Increased investment in case studies of particular programs at Federal laboratories and research on the public utility of a system of Federal laboratories could lead to increased productivity of laboratories. Elimination of risk-averse Federal laboratory and agency bureaucracies would also have dramatic impact on the productivity of the Federal laboratory system. Appropriately used, the US Federal laboratory system offers the US an innovative advantage over other nations.

  19. Cultura organizacional no setor público: um estudo junto a um departamento administrativo de uma universidade federal brasileira Organizational Culture In The Public Administration: A Study In Administrative Department Of Brazilian Federal University

    Directory of Open Access Journals (Sweden)

    Evandro Dotto Dias

    2011-12-01

    Full Text Available The organizacional culture is a complex subject and that constantly it comes being studied for specialists and researchers of the whole world, for the fact of its relevance in the understanding of the functioning of the organizations. However, this type of study not yet total was spread out in the Brazilian public organizations, mainly in federal universities. Therefore, the present work has as objective generality to identify to the organizacional culture under the personal and institucional points of view in an managemental department of the Federal University of Saint Maria, through a comparison with four deuses Greek (Zeus, Apolo, Atena and Dionísio that they reflect the form as the politics and strategies in an organization are lead, according to Handy study (1994. By means of a survey carried through with the employees of the related department, the gotten results had allowed the conclusion of that it has the predominance of the organizacional culture of the Apolo type in the institucional optics and of the Atena type in the personal optics, where a made comparative degree enter the predominant characteristics in each one of these cultures showed a divergence enter the yearnings of the collaborators and the form as the organization acts day-by-day in its, as the points boarded for the research and presented in the analysis of the results.A cultura organizacional é um tema complexo e constantemente em estudo por especialistas e pesquisadores de todo o mundo, pela sua relevância na compreensão do funcionamento das organizações. No entanto, esse tipo de estudo ainda não foi totalmente difundido nas organizações públicas brasileiras, principalmente em universidades federais. Por isso, este trabalho tem como objetivo geral identificar a cultura organizacional sob os pontos de vista pessoal e institucional em um departamento administrativo da Universidade Federal de Santa Maria, através de uma relação com os quatro deuses gregos

  20. Federal Fleet Report

    Data.gov (United States)

    General Services Administration — Annual report of Federal agencies' motor vehicle fleet data collected in the Federal Automotive Statistical Tool (FAST), a web-based reporting tool cosponsored by...

  1. TAP Service Federation Factory

    Science.gov (United States)

    Hume, A. C.; Krause, A.; Holliman, M.; Mann, R. G.; Noddle, K.; Voutsinas, S.

    2012-09-01

    This paper describes a prototype federation service for multiple TAP endpoints. Users can create a new TAP resource that allows them to query the federation as if all tables were in a single database.

  2. Differential impact of local and federal smoke-free legislation in Mexico: a longitudinal study among adult smokers.

    Science.gov (United States)

    Thrasher, James F; Swayampakala, Kamala; Arillo-Santillán, Edna; Sebrié, Ernesto; Walsemann, Katrina M; Bottai, Matteo

    2010-01-01

    To assess the impact of Mexico City and federal smoke-free legislation on secondhand tobacco smoke (SHS) exposure and support for smoke-free laws. Pre- and post-law data were analyzed from a cohort of adult smokers who participated in the International Tobacco Control (ITC) Policy Evaluation Suvey in four Mexican cities. For each indicator, we estimated prevalence, changes in prevalence, and between-city differences in rates of change. Self-reported exposure to smoke-free media campaigns generally increased more dramatically in Mexico City. Support for prohibiting smoking in regulated venues increased overall, but at a greater rate in Mexico City than in other cities. In bars and restaurants/cafés, self-reported SHS exposure had significantly greater decreases in Mexico City than in other cities; however, workplace exposure decreased in Tijuana and Guadalajara, but not in Mexico City or Ciudad Juárez. Although federal smoke-free legislation was associated with important changes smoke-free policy impact, the comprehensive smoke-free law in Mexico City was generally accompanied by a greater rate of change.

  3. Federalism in Pakistan, Current Developments

    Directory of Open Access Journals (Sweden)

    Razia Musarrat

    2012-04-01

    Full Text Available Purpose of this study is to elaborate the political issues and challenges faces by the federation of Pakistan during and after the Gen. Pervez Musharraf government. In this paper effort is made to discuss those issues on the biases of which politics of federalism started in the country. Pinching problems that caused disintegration to Pakistan are also discussed. Those issues are also discussed in details which are a constant threat to the “new federation of Pakistan”. Authors also focus on the 2008 elections and its consequences on Pakistan politics. All the results of this research are proved via review of the previous literature. Researchers have proved that as Pakistan has a diversified culture so federalism is best suited for its political structure. Researchers have also discussed few suggestive solutions for better bureaucracy.

  4. Future climate change will favour non-specialist mammals in the (sub)arctics.

    Science.gov (United States)

    Hof, Anouschka R; Jansson, Roland; Nilsson, Christer

    2012-01-01

    Arctic and subarctic (i.e., [sub]arctic) ecosystems are predicted to be particularly susceptible to climate change. The area of tundra is expected to decrease and temperate climates will extend further north, affecting species inhabiting northern environments. Consequently, species at high latitudes should be especially susceptible to climate change, likely experiencing significant range contractions. Contrary to these expectations, our modelling of species distributions suggests that predicted climate change up to 2080 will favour most mammals presently inhabiting (sub)arctic Europe. Assuming full dispersal ability, most species will benefit from climate change, except for a few cold-climate specialists. However, most resident species will contract their ranges if they are not able to track their climatic niches, but no species is predicted to go extinct. If climate would change far beyond current predictions, however, species might disappear. The reason for the relative stability of mammalian presence might be that arctic regions have experienced large climatic shifts in the past, filtering out sensitive and range-restricted taxa. We also provide evidence that for most (sub)arctic mammals it is not climate change per se that will threaten them, but possible constraints on their dispersal ability and changes in community composition. Such impacts of future changes in species communities should receive more attention in literature.

  5. Future climate change will favour non-specialist mammals in the (subarctics.

    Directory of Open Access Journals (Sweden)

    Anouschka R Hof

    Full Text Available Arctic and subarctic (i.e., [sub]arctic ecosystems are predicted to be particularly susceptible to climate change. The area of tundra is expected to decrease and temperate climates will extend further north, affecting species inhabiting northern environments. Consequently, species at high latitudes should be especially susceptible to climate change, likely experiencing significant range contractions. Contrary to these expectations, our modelling of species distributions suggests that predicted climate change up to 2080 will favour most mammals presently inhabiting (subarctic Europe. Assuming full dispersal ability, most species will benefit from climate change, except for a few cold-climate specialists. However, most resident species will contract their ranges if they are not able to track their climatic niches, but no species is predicted to go extinct. If climate would change far beyond current predictions, however, species might disappear. The reason for the relative stability of mammalian presence might be that arctic regions have experienced large climatic shifts in the past, filtering out sensitive and range-restricted taxa. We also provide evidence that for most (subarctic mammals it is not climate change per se that will threaten them, but possible constraints on their dispersal ability and changes in community composition. Such impacts of future changes in species communities should receive more attention in literature.

  6. De-novo CD5 + B- prolymphocytic leukemia (PLL) presenting at younger age with favourable outcome.

    Science.gov (United States)

    Kar, Rakhee; Kumar, Rajat; Tyagi, Seema

    2008-09-05

    B-cell prolymphocytic leukemia (B-PLL) comprises 1% of chronic lymphocytic leukemias. CD5 positivity is seen in 1/3rd of cases which generally arise from pre existing CLL. They have longer median survival compared with de novo B-PLL which are commonly CD5 negative and are more aggressive with an older age of presentation. Herewith, we describe a 48-year-old male of de-novo CD5+ B-PLL presenting with minimal lymphadenopathy and massive splenomegaly with 90% atypical lymphoid cells in the peripheral smear and bone marrow. Immunophenotyping was strongly positive for CD5, CD45, CD19, CD22, FMC-7, S-Ig and CD38, moderately positive for CD 11c, weakly positive for CD23 and negative for CD-103 and ZAP 70. The patient responded well to fludarabine and cyclophosphamide and had an uneventful hospital course. Our case illustrates a de-novo B-PLL with aberrant CD5 positivity who had a short duration of illness, younger age at presentation and favourable treatment outcome.

  7. Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males.

    Science.gov (United States)

    Løvlie, Hanne; Gillingham, Mark A F; Worley, Kirsty; Pizzari, Tommaso; Richardson, David S

    2013-10-22

    Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus gallus, bias sperm use in favour of unrelated males. Here, we experimentally investigate whether this bias is driven by relatedness per se, or by similarity at the major histocompatibility complex (MHC), genes central to vertebrate acquired immunity, where polymorphism is critical to an individual's ability to combat pathogens. Through experimentally controlled natural matings, we confirm that selection against related males' sperm occurs within the female reproductive tract but demonstrate that this is more accurately predicted by MHC similarity: controlling for relatedness per se, more sperm reached the eggs when partners were MHC--dissimilar. Importantly, this effect appeared largely owing to similarity at a single MHC locus (class I minor). Further, the effect of MHC similarity was lost following artificial insemination, suggesting that male phenotypic cues might be required for females to select sperm differentially. These results indicate that postmating mechanisms that reduce inbreeding may do so as a consequence of more specific strategies of cryptic female choice promoting MHC diversity in offspring.

  8. Soft Gamma-ray selected radio galaxies: favouring giant size discovery

    CERN Document Server

    Bassani, L; Molina, M; Malizia, A; Dallacasa, D; Panessa, F; Bazzano, A; Ubertini, P

    2016-01-01

    Using the recent INTEGRAL/IBIS and Swift/BAT surveys we have extracted a sample of 64 confirmed plus 3 candidate radio galaxies selected in the soft gamma-ray band. The sample covers all optical classes and is dominated by objects showing a FR II radio morphology; a large fraction (70%) of the sample is made of radiative mode or High Excitation Radio Galaxies (HERG). We have measured the source size on NVSS, FIRST and SUMSS images and have compared our findings with data in the literature obtaining a good match. We surprisingly found that the soft gamma-ray selection favours the detection of large size radio galaxies: 60% of objects in the sample have size greater than 0.4 Mpc while around 22% reach dimension above 0.7 Mpc at which point they are classified as Giant Radio Galaxies or GRGs, the largest and most energetic single entities in the Universe. Their fraction among soft gamma ray selected radio galaxies is significantly larger than typically found in radio surveys, where only a few percent of objects ...

  9. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity.

    Science.gov (United States)

    Guerau-de-Arellano, Mireia; Smith, Kristen M; Godlewski, Jakub; Liu, Yue; Winger, Ryan; Lawler, Sean E; Whitacre, Caroline C; Racke, Michael K; Lovett-Racke, Amy E

    2011-12-01

    Pro-inflammatory T cells mediate autoimmune demyelination in multiple sclerosis. However, the factors driving their development and multiple sclerosis susceptibility are incompletely understood. We investigated how micro-RNAs, newly described as post-transcriptional regulators of gene expression, contribute to pathogenic T-cell differentiation in multiple sclerosis. miR-128 and miR-27b were increased in naïve and miR-340 in memory CD4(+) T cells from patients with multiple sclerosis, inhibiting Th2 cell development and favouring pro-inflammatory Th1 responses. These effects were mediated by direct suppression of B lymphoma Mo-MLV insertion region 1 homolog (BMI1) and interleukin-4 (IL4) expression, resulting in decreased GATA3 levels, and a Th2 to Th1 cytokine shift. Gain-of-function experiments with these micro-RNAs enhanced the encephalitogenic potential of myelin-specific T cells in experimental autoimmune encephalomyelitis. In addition, treatment of multiple sclerosis patient T cells with oligonucleotide micro-RNA inhibitors led to the restoration of Th2 responses. These data illustrate the biological significance and therapeutic potential of these micro-RNAs in regulating T-cell phenotypes in multiple sclerosis.

  10. Physiological responses to increased brood size and ectoparasite infestation: Adult great tits favour self-maintenance.

    Science.gov (United States)

    Wegmann, Michele; Voegeli, Beatrice; Richner, Heinz

    2015-03-15

    Different types of stressors trigger responses of different physiological systems, and these responses may contribute differentially to the maintenance of homeostasis, to trade-offs and the evolution of life-history traits. To manipulate two common stressors during reproduction, we infested half of the nests in a naturally breeding great tit population with ectoparasites and simultaneously manipulated brood size, using a 2×2 experimental design. Parents in this model species commonly compensate for ectoparasites by an increase in food provisioning. We assessed parental responses to these concurrent stressors by measuring several physiological stress parameters such as changes in metabolic rate, oxidative stress and expression of heat-shock proteins (Hsp), and explored how these stressors affect the trade-off between self-maintenance and reproduction. Neither flea infestation nor brood size manipulation affected adult metabolic rate, oxidative damage or Hsp levels. Furthermore, we found no interactive effect of the two treatments on adults. However, nestlings in infested nests had lower body mass and lower survival. Nestlings in enlarged broods were lighter and had lower survival, although parents of enlarged broods increased food provisioning rate. The findings suggest that adults favour maintenance of cellular homeostasis, and physiological equilibrium over current reproduction, and that the costs induced by both stressors, flea infestation and increased brood size, are carried by the offspring. It emphasizes the importance of self-maintenance over reproduction in life-history decisions, and more generally the need of including physiological traits for understanding the evolution of life-histories.

  11. Identifying the environmental conditions favouring West Nile Virus outbreaks in Europe.

    Directory of Open Access Journals (Sweden)

    Matteo Marcantonio

    Full Text Available West Nile Virus (WNV is a globally important mosquito borne virus, with significant implications for human and animal health. The emergence and spread of new lineages, and increased pathogenicity, is the cause of escalating public health concern. Pinpointing the environmental conditions that favour WNV circulation and transmission to humans is challenging, due both to the complexity of its biological cycle, and the under-diagnosis and reporting of epidemiological data. Here, we used remote sensing and GIS to enable collation of multiple types of environmental data over a continental spatial scale, in order to model annual West Nile Fever (WNF incidence across Europe and neighbouring countries. Multi-model selection and inference were used to gain a consensus from multiple linear mixed models. Climate and landscape were key predictors of WNF outbreaks (specifically, high precipitation in late winter/early spring, high summer temperatures, summer drought, occurrence of irrigated croplands and highly fragmented forests. Identification of the environmental conditions associated with WNF outbreaks is key to enabling public health bodies to properly focus surveillance and mitigation of West Nile virus impact, but more work needs to be done to enable accurate predictions of WNF risk.

  12. Identifying the environmental conditions favouring West Nile Virus outbreaks in Europe.

    Science.gov (United States)

    Marcantonio, Matteo; Rizzoli, Annapaola; Metz, Markus; Rosà, Roberto; Marini, Giovanni; Chadwick, Elizabeth; Neteler, Markus

    2015-01-01

    West Nile Virus (WNV) is a globally important mosquito borne virus, with significant implications for human and animal health. The emergence and spread of new lineages, and increased pathogenicity, is the cause of escalating public health concern. Pinpointing the environmental conditions that favour WNV circulation and transmission to humans is challenging, due both to the complexity of its biological cycle, and the under-diagnosis and reporting of epidemiological data. Here, we used remote sensing and GIS to enable collation of multiple types of environmental data over a continental spatial scale, in order to model annual West Nile Fever (WNF) incidence across Europe and neighbouring countries. Multi-model selection and inference were used to gain a consensus from multiple linear mixed models. Climate and landscape were key predictors of WNF outbreaks (specifically, high precipitation in late winter/early spring, high summer temperatures, summer drought, occurrence of irrigated croplands and highly fragmented forests). Identification of the environmental conditions associated with WNF outbreaks is key to enabling public health bodies to properly focus surveillance and mitigation of West Nile virus impact, but more work needs to be done to enable accurate predictions of WNF risk.

  13. Amplified mid-latitude planetary waves favour particular regional weather extremes

    Science.gov (United States)

    Screen, James A.; Simmonds, Ian

    2014-08-01

    There has been an ostensibly large number of extreme weather events in the Northern Hemisphere mid-latitudes during the past decade. An open question that is critically important for scientists and policy makers is whether any such increase in weather extremes is natural or anthropogenic in origin. One mechanism proposed to explain the increased frequency of extreme weather events is the amplification of mid-latitude atmospheric planetary waves. Disproportionately large warming in the northern polar regions compared with mid-latitudes--and associated weakening of the north-south temperature gradient--may favour larger amplitude planetary waves, although observational evidence for this remains inconclusive. A better understanding of the role of planetary waves in causing mid-latitude weather extremes is essential for assessing the potential environmental and socio-economic impacts of future planetary wave changes. Here we show that months of extreme weather over mid-latitudes are commonly accompanied by significantly amplified quasi-stationary mid-tropospheric planetary waves. Conversely, months of near-average weather over mid-latitudes are often accompanied by significantly attenuated waves. Depending on geographical region, certain types of extreme weather (for example, hot, cold, wet, dry) are more strongly related to wave amplitude changes than others. The findings suggest that amplification of quasi-stationary waves preferentially increases the probabilities of heat waves in western North America and central Asia, cold outbreaks in eastern North America, droughts in central North America, Europe and central Asia, and wet spells in western Asia.

  14. January 2016 extensive summer melt in West Antarctica favoured by strong El Niño

    Science.gov (United States)

    Nicolas, Julien P.; Vogelmann, Andrew M.; Scott, Ryan C.; Wilson, Aaron B.; Cadeddu, Maria P.; Bromwich, David H.; Verlinde, Johannes; Lubin, Dan; Russell, Lynn M.; Jenkinson, Colin; Powers, Heath H.; Ryczek, Maciej; Stone, Gregory; Wille, Jonathan D.

    2017-06-01

    Over the past two decades the primary driver of mass loss from the West Antarctic Ice Sheet (WAIS) has been warm ocean water underneath coastal ice shelves, not a warmer atmosphere. Yet, surface melt occurs sporadically over low-lying areas of the WAIS and is not fully understood. Here we report on an episode of extensive and prolonged surface melting observed in the Ross Sea sector of the WAIS in January 2016. A comprehensive cloud and radiation experiment at the WAIS ice divide, downwind of the melt region, provided detailed insight into the physical processes at play during the event. The unusual extent and duration of the melting are linked to strong and sustained advection of warm marine air toward the area, likely favoured by the concurrent strong El Niño event. The increase in the number of extreme El Niño events projected for the twenty-first century could expose the WAIS to more frequent major melt events.

  15. Relax and refill: xylem rehydration prior to hydraulic measurements favours embolism repair in stems and generates artificially low PLC values.

    Science.gov (United States)

    Trifilò, Patrizia; Raimondo, Fabio; Lo Gullo, Maria A; Barbera, Piera M; Salleo, Sebastiano; Nardini, Andrea

    2014-11-01

    Diurnal changes in percentage loss of hydraulic conductivity (PLC), with recorded values being higher at midday than on the following morning, have been interpreted as evidence for the occurrence of cycles of xylem conduits' embolism and repair. Recent reports have suggested that diurnal PLC changes might arise as a consequence of an experimental artefact, that is, air entry into xylem conduits upon cutting stems, even if under water, while under substantial tension generated by transpiration. Rehydration procedures prior to hydraulic measurements have been recommended to avoid this artefact. In the present study, we show that xylem rehydration prior to hydraulic measurements might favour xylem refilling and embolism repair, thus leading to PLC values erroneously lower than those actually experienced by transpiring plants. When xylem tension relaxation procedures were performed on stems where refilling mechanisms had been previously inhibited by mechanical (girdling) or chemical (orthovanadate) treatment, PLC values measured in stems cut under native tension were the same as those measured after sample rehydration/relaxation. Our data call for renewed attention to the procedures of sample collection in the field and transport to the laboratory, and suggest that girdling might be a recommendable treatment prior to sample collection for PLC measurements.

  16. Organic farming favours insect-pollinated over non-insect pollinated forbs in meadows and wheat fields.

    Science.gov (United States)

    Batáry, Péter; Sutcliffe, Laura; Dormann, Carsten F; Tscharntke, Teja

    2013-01-01

    The aim of this study was to determine the relative effects of landscape-scale management intensity, local management intensity and edge effect on diversity patterns of insect-pollinated vs. non-insect pollinated forbs in meadows and wheat fields. Nine landscapes were selected differing in percent intensively used agricultural area (IAA), each with a pair of organic and conventional winter wheat fields and a pair of organic and conventional meadows. Within fields, forbs were surveyed at the edge and in the interior. Both diversity and cover of forbs were positively affected by organic management in meadows and wheat fields. This effect, however, differed significantly between pollination types for species richness in both agroecosystem types (i.e. wheat fields and meadows) and for cover in meadows. Thus, we show for the first time in a comprehensive analysis that insect-pollinated plants benefit more from organic management than non-insect pollinated plants regardless of agroecosystem type and landscape complexity. These benefits were more pronounced in meadows than wheat fields. Finally, the community composition of insect-pollinated and non-insect-pollinated forbs differed considerably between management types. In summary, our findings in both agroecosystem types indicate that organic management generally supports a higher species richness and cover of insect-pollinated plants, which is likely to be favourable for the density and diversity of bees and other pollinators.

  17. The evolution of colour pattern complexity: selection for conspicuousness favours contrasting within-body colour combinations in lizards.

    Science.gov (United States)

    Pérez I de Lanuza, G; Font, E

    2016-05-01

    Many animals display complex colour patterns that comprise several adjacent, often contrasting colour patches. Combining patches of complementary colours increases the overall conspicuousness of the complex pattern, enhancing signal detection. Therefore, selection for conspicuousness may act not only on the design of single colour patches, but also on their combination. Contrasting long- and short-wavelength colour patches are located on the ventral and lateral surfaces of many lacertid lizards. As the combination of long- and short-wavelength-based colours generates local chromatic contrast, we hypothesized that selection may favour the co-occurrence of lateral and ventral contrasting patches, resulting in complex colour patterns that maximize the overall conspicuousness of the signal. To test this hypothesis, we performed a comparative phylogenetic study using a categorical colour classification based on spectral data and descriptive information on lacertid coloration collected from the literature. Our results demonstrate that conspicuous ventral (long-wavelength-based) and lateral (short-wavelength-based) colour patches co-occur throughout the lacertid phylogeny more often than expected by chance, especially in the subfamily Lacertini. These results suggest that selection promotes the evolution of the complex pattern rather than the acquisition of a single conspicuous colour patch, possibly due to the increased conspicuousness caused by the combination of colours with contrasting spectral properties.

  18. A novel organometallic ReI complex with favourable properties for bioimaging and applicability in solid-phase peptide synthesis.

    Science.gov (United States)

    Raszeja, Lukasz; Maghnouj, Abdelouahid; Hahn, Stephan; Metzler-Nolte, Nils

    2011-02-11

    Organometallic complexes possess great potential for imaging applications in biology, due to their kinetic stability and often favourable intrinsic properties. In this work we present a new class of Re(I) -tricarbonyl complexes with a substituted bis(phenanthridinylmethyl)amine (bpm) ligand. The complex Re(CO)(3) (R-bpm) could be conveniently prepared by microwave synthesis from [Re(CO)(3)(H(2)O)(3) ]Br and a suitably substituted bis(phenanthridinylmethyl)amine (R-bpm). Complex 5, with R=CH(2)-CO(2)-CH(3) , was characterized by a single-crystal X-ray structure. Complex 6 (R=CH(2)-C(6)H(4)-CO(2)H) was used in solid-phase peptide synthesis (SPPS) to label the neurotensin(8-13) (NT) fragment N-terminally. The complexes show luminescence emission with large Stokes shifts (λ(ex) =350 nm, λ(em) =570 nm). Cellular uptake and intracellular localization studies in several cell lines demonstrate the utility of the new Re(CO)(3) (R-bpm) complexes for fluorescence imaging and reveal significant differences between the simple methyl ester 5 and the NT bioconjugate 7.

  19. Testing the efficacy of downscaling in species distribution modelling: a comparison between MaxEnt and Favourability Function models

    Energy Technology Data Exchange (ETDEWEB)

    Olivero, J.; Toxopeus, A.G.; Skidmore, A.K.; Real, R.

    2016-07-01

    Statistical downscaling is used to improve the knowledge of spatial distributions from broad–scale to fine–scale maps with higher potential for conservation planning. We assessed the effectiveness of downscaling in two commonly used species distribution models: Maximum Entropy (MaxEnt) and the Favourability Function (FF). We used atlas data (10 x 10 km) of the fire salamander Salamandra salamandra distribution in southern Spain to derive models at a 1 x 1 km resolution. Downscaled models were assessed using an independent dataset of the species’ distribution at 1 x 1 km. The Favourability model showed better downscaling performance than the MaxEnt model, and the models that were based on linear combinations of environmental variables performed better than models allowing higher flexibility. The Favourability model minimized model overfitting compared to the MaxEnt model. (Author)

  20. Favourable areas for expansion and reintroduction of Iberian lynx accounting for distribution trends and genetic variation of the wild rabbit

    Directory of Open Access Journals (Sweden)

    A. Márcia Barbosa

    2010-12-01

    Full Text Available Although on a local scale Iberian lynx distribution is determined by the availability of prey rabbits, recent modelling analyses have uncovered broad-scale disagreements between these two species’ distribution trends. These analyses showed also that the lynx had become restricted to only a fraction of the rabbit’s genetic variability, and that this could be jeopardising its survival in the face of environmental hazards and uncertainty. In the present paper, a follow-up was carried out through the building of lynx and rabbit distribution models based on the most recent Spanish mammal atlas. The predictions of environmental favourability (which is an indicator of abundance for lynx and rabbit were positively correlated within the lynx's current distribution area, but they were negatively correlated within the total Spanish area where lynx occurred in the 1980’s. Environmental favourability for rabbits was significantly higher where lynx maintains reproductive populations than where it recently disappeared, indicating that rabbit favourability plays an important role and can be a good predictor of lynx persistence. The lynx and rabbit models were extrapolated to predict favourable areas for both species in Spain as well as in Portugal, on the original scale of the distribution data (10x10 km and on a 100 times finer spatial resolution (1x1 km. The lynx and rabbit models were also combined through fuzzy logic to forecast the potential for lynx occurrence incorporating information on favourable areas for its main prey. Several areas are proposed as favourable for lynx expansion or re-introduction, encompassing both countries and both genetic lineages of the rabbit.

  1. Higher maternal education is associated with favourable growth of young children in different countries

    Science.gov (United States)

    Lakshman, Rajalakshmi; Zhang, Jing; Zhang, Jianduan; Koch, Felix S; Marcus, Claude; Ludvigsson, Johnny; Ong, Ken K; Sobko, Tanja

    2013-01-01

    Background Childhood growth affects long-term health and could contribute to health inequalities that persist throughout life. Methods We compared growth data of 4-6 year old children born 1997-2002 in UK (n=15,168), Sweden (n=6,749) and rural China (n=10,327). Standard deviation scores (SDS) were calculated against the WHO Standard. Obesity and overweight were defined by International Obesity Taskforce cut-offs, and stunting, underweight and thinness by height, weight or BMI < −2 SDS. Associations with maternal education were standardised by calculating the Slope Index of Inequality (SII). Results Mean SDS height, weight and BMI in UK (−0.01; 0.42; 0.62, respectively) and Sweden (0.45; 0.59; 0.45) were higher than in China (−0.98, −0.82, −0.29). Higher maternal education was consistently associated with taller offspring height SDS (SII: UK 0.25; Sweden 0.17; China 1.06). Underweight and stunting were less common in UK (prevalence: 0.6% and 2.2%, respectively) and Sweden (0.3% and 0.6%) than in China (9.5% and 16.4%), where these outcomes were inversely associated with maternal education (SII: −25.8% and −12.7%). Obesity prevalence in UK, Sweden and China was 4.8%, 3.7% and 0.4%, respectively. Maternal education was inversely associated with offspring obesity in UK (SII: −3.3%) and Sweden (−2.8%), but not in China (+0.3%). Conclusions Higher maternal education was associated with more favourable growth in young children: lower obesity and overweight in UK and Sweden, and lower stunting and underweight in rural China. Public health strategies to optimize growth in early childhood need to acknowledge socioeconomic factors, but possibly with a different emphasis in different settings. PMID:23450064

  2. Harmful and favourable ultraviolet conditions for human health over Northern Eurasia

    Science.gov (United States)

    Chubarova, Nataly; Zhdanova, Ekaterina

    2014-05-01

    We provide the analysis of the spatial and temporal distribution of ultraviolet (UV) radiation over Northern Eurasia taking into account for both its detrimental (erythema and eye-damage effects) and favourable (vitamin D synthesis) influence on human health. The UV effects on six different skin types are considered in order to cover the variety of skin types of European and Asian inhabitants. To better quantifying the vitamin D irradiance threshold we accounted for an open body fraction S as a function of effective air temperature. The spatial and temporal distribution of UV resources was estimated by radiative transfer (RT) modeling (8 stream DISORT RT code) with 1x 1 degree grid and monthly resolution. For this purpose special datasets of main input geophysical parameters (total ozone content, aerosol characteristics, surface UV albedo, UV cloud modification factor) have been created over the territory of Northern Eurasia, which can be of separate interest for the different multidisciplinary scientific applications over the PEEX domain. The new approaches were used to retrieve aerosol and cloud transmittance from different satellite and re-analysis datasets for calculating the solar UV irradiance at ground. Using model simulations and some experimental data we provide the altitude parameterization for different types of biologically active irradiance in mountainous area taking into account not only for the effects of molecular scattering but for the altitude dependence of aerosol parameters and surface albedo. Based on the new classification of UV resources (Chubarova, Zhdanova, 2013) we show that the distribution of harmful (UV deficiency and UV excess) and favorable UV conditions is regulated by various geophysical parameters (mainly, total ozone, cloudiness and open body fraction) and can significantly deviate from latitudinal dependence. The interactive tool for providing simulations of biologically active irradiance and its attribution to the different

  3. Os programas de inclusão digital do Governo Federal sob a óptica da competência informacional | Federal digital inclusion programmes from the viewpoint of informational competency

    Directory of Open Access Journals (Sweden)

    Elaine R. de Oliveira Lucas

    2009-04-01

    Full Text Available Resumo Apresenta um estudo sobre como o Governo Federal trabalha as desigualdades causadas pela exclusão digital. Neste contexto foram mapeadas as iniciativas públicas em inclusão digital na esfera federal, nos últimos dez anos considerando-as sob a óptica do conceito de competência informacional. Constatou-se que a política de governo eletrônico brasileiro está atrelada às iniciativas de inclusão digital e que o setor federal brasileiro está investindo na construção de uma infra-estrutura tecnológica de acesso e na capacitação tecnológica do cidadão. Ademais, cabe ainda ao Governo Federal aumentar os investimentos nas ações que possibilitam as camadas menos favorecidas da sociedade desenvolverem competências necessárias para o uso efetivo da informação, como recurso para o exercício da cidadania. Palavras-chave inclusão digital; competência informacional; governo eletrônico; exercício da cidadania; tecnologia da informação Abstract This is a study on how the Federal Government faces inequalities caused by digital exclusion (or “digital divide”. It maps out public initiatives in digital inclusion in the federal sphere in the last ten years, considered from the point of view of the concept of “informational competency”. Brazilian e-government policy is tied to digital inclusion and the federal government invests in building a technlogical acces infrastructure and in technological citizenship. Moreover, the government must increase investment in actions allowing least-favoured strata of society to develop the necessary competencies for the effective use of information as a resource for citizenship. Keywords digital inclusion; informational competency; electronic government; citizenship; information technology

  4. Integrating systematic screening for gender-based violence into sexual and reproductive health services: results of a baseline study by the International Planned Parenthood Federation, Western Hemisphere Region.

    Science.gov (United States)

    Guedes, A; Bott, S; Cuca, Y

    2002-09-01

    Three Latin American affiliates of the International Planned Parenthood Federation, Western Hemisphere Region, Inc. (IPPF/WHR) have begun to integrate gender-based violence screening and services into sexual and reproductive health programs. This paper presents results of a baseline study conducted in the affiliates. Although most staff support integration and many had already begun to address violence in their work, additional sensitization and training, as well as institution-wide changes are needed to provide services effectively and to address needs of women experiencing violence.

  5. Heterosis may result in selection favouring the products of long-distance pollen dispersal in Eucalyptus.

    Directory of Open Access Journals (Sweden)

    João Costa E Silva

    Full Text Available Using native trees from near the northern and southern extremities of the relatively continuous eastern distribution of Eucalyptus globulus in Tasmania, we compared the progenies derived from natural open-pollination (OP with those generated from within-region and long-distance outcrossing. Controlled outcrossing amongst eight parents - with four parents from each of the northern and southern regions - was undertaken using a diallel mating scheme. The progeny were planted in two field trials located within the species native range in southern Tasmania, and their survival and diameter growth were monitored over a 13-year-period. The survival and growth performances of all controlled cross types exceeded those of the OP progenies, consistent with inbreeding depression due to a combination of selfing and bi-parental inbreeding. The poorer survival of the northern regional (♀N♂N outcrosses compared with the local southern regional outcrosses (♀S♂S indicated differential selection against the former. Despite this mal-adaptation of the non-local ♀N♂N crosses at both southern sites, the survival of the inter-regional hybrids (♀N♂S and ♀S♂N was never significantly different from that of the local ♀S♂S crosses. Significant site-dependent heterosis was detected for the growth of the surviving long-distance hybrids. This was expressed as mid-parent heterosis, particularly at the more northern planting site. Heterosis increased with age, while the difference between the regional ♀N♂N and ♀S♂S crosses remained insignificant at any age at either site. Nevertheless, the results for growth suggest that the fitness of individuals derived from long-distance crossing may be better at the more northern of the planting sites. Our results demonstrate the potential for early-age assessments of pollen dispersal to underestimate realised gene flow, with local inbreeding under natural open-pollination resulting in selection favouring the

  6. The effects of defoliation on carbon allocation: can carbon limitation reduce growth in favour of storage?

    Science.gov (United States)

    Wiley, Erin; Huepenbecker, Sarah; Casper, Brenda B; Helliker, Brent R

    2013-11-01

    There is no consensus about how stresses such as low water availability and temperature limit tree growth. Sink limitation to growth and survival is often inferred if a given stress does not cause non-structural carbohydrate (NSC) concentrations or levels to decline along with growth. However, trees may actively maintain or increase NSC levels under moderate carbon stress, making the pattern of reduced growth and increased NSCs compatible with carbon limitation. To test this possibility, we used full and half defoliation to impose severe and moderate carbon limitation on 2-year-old Quercus velutina Lam. saplings grown in a common garden. Saplings were harvested at either 3 weeks or 4 months after treatments were applied, representing short- and longer-term effects on woody growth and NSC levels. Both defoliation treatments maintained a lower total leaf area than controls throughout the experiment with no evidence of photosynthetic up-regulation, and resulted in a similar total biomass reduction. While fully defoliated saplings had lower starch levels than controls in the short term, half defoliated saplings maintained control starch levels in both the short and longer term. In the longer term, fully defoliated saplings had the greatest starch concentration increment, allowing them to recover to near-control starch levels. Furthermore, between the two harvest dates, fully and half defoliated saplings allocated a greater proportion of new biomass to starch than did controls. The maintenance of control starch levels in half defoliated saplings indicates that these trees actively store a substantial amount of carbon before growth is carbon saturated. In addition, the allocation shift favouring storage in defoliated saplings is consistent with the hypothesis that, as an adaptation to increasing carbon stress, trees can prioritize carbon reserve formation at the expense of growth. Our results suggest that as carbon limitation increases, reduced growth is not necessarily

  7. Does the Higgs mechanism favour electron-electron bound states in Maxwell-Chern-Simons $QED_{3}$?

    CERN Document Server

    Belich, H; Helayël-Neto, José A

    2000-01-01

    The low-energy electron-electron scattering potential is derived and discussed for the Maxwell-Chern-Simons model coupled to QED_3 with spontaneous symmetry breaking. One shows that the Higgs mechanism might favour electron-electron bound states.

  8. The role of EU agri-environmental measures preserving extensive grazing in two less-favoured areas in Portugal

    NARCIS (Netherlands)

    Jones, Nádia; Duarte, Filomena; Rodrigo, Isabel; Doorn, van Anne; Graaff, de Jan

    2016-01-01

    Since 1992 agri-environmental issues have gained attention by reforms of the CAP. For instance by supporting environmentally friendly land use, such as permanent pastures in less-favoured areas (LFA) that are only marginally suitable for alternative farming practices. In the last two decades a si

  9. Local food policies can help promote local foods and improve health: a case study from the Federated States of Micronesia.

    Science.gov (United States)

    Englberger, Lois; Lorens, Adelino; Pretrick, Moses; Tara, Mona J; Johnson, Emihner

    2011-11-01

    The Federated States of Micronesia (FSM) and other countries throughout the Pacific are facing an epidemic of non-communicable disease health problems. These are directly related to the increased consumption of unhealthy imported processed foods, the neglect of traditional food systems, and lifestyle changes, including decreased physical activity. The FSM faces the double burden of malnutrition with both non-communicable diseases and micronutrient deficiencies, including vitamin A deficiency and anemia. To help increase the use of traditional island foods and improve health, the Island Food Community of Pohnpei has initiated a program in the FSM to support and promote local food policies, along with its Go Local awareness campaign. Such local food policies are defined broadly and include individual and family commitments, community group local food policies and policies established by government, including presidential proclamations and increased taxation on soft drinks. The aim of this paper is to describe this work. An inter-agency, community- and research-based, participatory and media approach was used. Partners are both non-governmental and governmental. The use of continuing awareness work along with local food policy establishment and the acknowledgement of the individuals and groups involved are essential. The work is still in the preliminary stage but ad hoc examples show that this approach has had success in increased awareness on health issues and improving dietary intake on both an individual and group basis. This indicates that further use of local food policies could have an instrumental impact in FSM as well as other Pacific Island countries in promoting local foods and improving dietary intake and health, including the control of non-communicable diseases and other dietary-related health problems.

  10. AVTA Federal Fleet PEV Readiness Data Logging and Characterization Study for the United States Forest Service: Caribou-Targhee National Forest

    Energy Technology Data Exchange (ETDEWEB)

    Stephen Schey; Jim Francfort; Ian Nienhueser

    2014-06-01

    Battelle Energy Alliance, LLC, managing and operating contractor for the U.S. Department of Energy’s Idaho National Laboratory, is the lead laboratory for U.S. Department of Energy Advanced Vehicle Testing. Battelle Energy Alliance, LLC contracted with Intertek Testing Services, North America (ITSNA) to collect and evaluate data on federal fleet operations as part of the Advanced Vehicle Testing Activity’s Federal Fleet Vehicle Data Logging and Characterization study. The Advanced Vehicle Testing Activity study seeks to collect and evaluate data to validate the utilization of advanced electric drive vehicle transportation. This report focuses on the Caribou-Targhee National Forest (CTNF) fleet to identify daily operational characteristics of select vehicles and report findings on vehicle and mission characterizations to support the successful introduction of plug-in electric vehicles (PEVs) into the agencies’ fleets. Individual observations of these selected vehicles provide the basis for recommendations related to electric vehicle adoption and whether a battery electric vehicle (BEV) or plug-in hybrid electric vehicle (PHEV) (collectively plug-in electric vehicles, or PEVs) can fulfill the mission requirements. ITSNA acknowledges the support of Idaho National Laboratory and CTNF for participation in the study. ITSNA is pleased to provide this report and is encouraged by enthusiasm and support from the Forest Service and CTNF personnel.

  11. Putative IL-10 Low Producer Genotypes Are Associated with a Favourable Etanercept Response in Patients with Rheumatoid Arthritis.

    Directory of Open Access Journals (Sweden)

    Heiko Schotte

    Full Text Available Outcome predictors of biologic therapeutic drugs like TNF inhibitors are of interest since side effects like serious infections or malignancy cannot be completely ruled out. Response rates are heterogeneous. The present study addressed the question whether in patients with rheumatoid arthritis (RA interleukin-10 (IL-10 promoter genotypes with potential relevance for IL-10 production capacity are associated with response to long-term treatment with etanercept. Caucasian RA patients that, according to the EULAR criteria, responded well (n = 25, moderately (n = 17 or not (n = 8 to etanercept therapy (median 36 months, range 4-52, and 160 matched controls were genotyped for the IL-10 promoter SNPs -2849 G>A (rs6703630, -1082 G>A (rs1800896, -819 C>T (rs1800871 and -592 C>A (rs1800872. Haplotypes were reconstructed via mathematic model and tested for associations with disease susceptibility and therapy response. We identified the four predominant haplotypes AGCC, GATA, GGCC, and GACC in almost equal distribution. Patients that responded well carried the putative IL-10 low producer allele -2849 A or the haplotypes AGCC and GATA (RR 2.1 and 4.0, respectively; 95% CI 1.1-4.0 and 1.1-14.8, whereas an unfavourable response was associated with carriage of the putative high producer haplotype GGCC (RR 1.9, 95% CI 1.1-3.3. No significant associations of alleles or haplotypes with disease susceptibility were observed. In RA, a low IL-10 production which is genetically determined rather by haplotypes than by SNPs may favour the response to etanercept treatment. Iatrogenic blockade of TNF may reveal proinflammatory effects of its endogeneous antagonist IL-10. Further studies are needed to correlate these genetic findings to direct cytokine measurements.

  12. Foliar photochemical processes and carbon metabolism under favourable and adverse winter conditions in a Mediterranean mixed forest, Catalonia (Spain)

    Science.gov (United States)

    Sperlich, D.; Chang, C. T.; Peñuelas, J.; Gracia, C.; Sabaté, S.

    2014-06-01

    Evergreen trees in the Mediterranean region must cope with a wide range of environmental stresses from summer drought to winter cold. The mildness of Mediterranean winters can periodically lead to favourable environmental conditions above the threshold for a positive carbon balance, benefitting evergreen woody species more than deciduous ones. The comparatively lower solar energy input in winter decreases the foliar light saturation point. This leads to a higher susceptibility to photoinhibitory stress especially when chilly (change persisted for several weeks after the cold period despite the recovery of the temperature to the conditions previous to the frost event. The responses of Vc, max and Jmax were highly species-specific, where Q. ilex exhibited the highest and P. halepensis the lowest reductions. In contrast, the optimal fluorometric quantum yield of photosystem II (Fv/Fm) was significantly lower in A. unedo after the cold period. The leaf position played an important role in Q. ilex showing a comparatively stronger winter effect on sunlit leaves. Our results generally agreed with the previous classifications of photoinhibition-avoiding (P. halepensis) and photoinhibition-tolerant (Q. ilex) species on the basis of their susceptibility to dynamic photoinhibition, whereas A. unedo was the least tolerant to photoinhibition, which was chronic in this species. Q. ilex and P. halepensis seem to follow contrasting photoprotective strategies which are, however, equally successful under the prevailing conditions exhibiting an adaptive advantage over A. unedo in our study site. These results show that our understanding of the dynamics of interspecific competition in Mediterranean ecosystems requires consideration of the physiological behaviour during winter which may have important implications for long-term carbon budgets and growth trends.

  13. Persuading, protesting and exchanging favours: strategies used by Indian sex workers to win local support for their HIV prevention programmes.

    Science.gov (United States)

    Cornish, Flora; Shukla, Anuprita; Banerji, Riddhi

    2010-01-01

    Given that the communities which are most vulnerable to HIV often have little control over their own lives and their health-related behaviour, HIV prevention policies increasingly recommend that HIV prevention projects work to build relationships with powerful external groups (i.e., build "bridging social capital"). To aid conceptualisation of how community organisations may build such social capital, this paper outlines a typology of strategies for influencing local stakeholders. We present a study of two successful Indian sex workers' organisations, VAMP and DMSC, focusing on how the organisations have influenced three groups of stakeholders, namely police, politicians and local social organisations. Interviews with project employees (45), with representatives of the three groups of stakeholders (12) and fieldwork diaries recording 6 months of observation in each site provide the data. Three approaches emerged. "Persuading" refers to the practice of holding information-giving meetings with stakeholders and requesting their support. It appears to build "weak social ties". "Protesting" entails a collective confrontation with stakeholders, and appears to be useful when the stakeholder has a public image to protect that would be tarnished by protest, and when the protestors can stake a legitimate claim that their rights are being denied. In "exchanging favours", the sex workers' organisations find creative ways to position themselves as offering valued resources to their stakeholders (such as useful information on criminal activities for the police, a stage and audience for politicians or a celebration for local social organisations) as incentives for their support. In conclusion, we discuss the strengths and weaknesses of each approach, the implications for social capital theorising and implications for community HIV prevention.

  14. When a University Opens Itself to Diversity: A Brief Report on the Intercultural Formation Course for Indigenous Teachers, from the Federal University of Minas Gerais (UFMG), Brazil

    Science.gov (United States)

    Lobo de Rezende, Luisa Andrade

    2009-01-01

    The Federal University of Minas Gerais (Universidade Federal de Minas Gerais-UFMG), located in the city of Belo Horizonte in Brazil, has been a committed partner of indigenous communities since 1996. This partnership began with the creation of spaces intended to elaborate and transform the traditional wisdom of these communities in favour of their…

  15. Low-cost and no-cost practice to achieve energy efficiency of government office buildings: A case study in federal territory of Malaysia

    Science.gov (United States)

    Tahir, Mohamad Zamhari; Nawi, Mohd Nasrun Mohd; Ibrahim, Amlus

    2016-08-01

    This paper presents the findings of a case study to achieve energy-efficient performance of conventional office buildings in Malaysia. Two multi-storey office buildings in Federal Territory of Malaysia have been selected. The aim is to study building energy saving potential then to highlight the appropriate measures that can be implemented. Data was collected using benchmarking method by comparing the measured consumption to other similar office buildings and a series of preliminary audit which involves interviews, a brief review of utility and operating data as well as a walkthrough in the buildings. Additionally, in order to get a better understanding of major energy consumption in the selected buildings, general audit have been conducted to collect more detailed information about building operation. In the end, this study emphasized low-cost and no-cost practice to achieve energy efficiency with significant results in some cases.

  16. Measuring efficiency among US federal hospitals.

    Science.gov (United States)

    Harrison, Jeffrey P; Meyer, Sean

    2014-01-01

    This study evaluates the efficiency of federal hospitals, specifically those hospitals administered by the US Department of Veterans Affairs and the US Department of Defense. Hospital executives, health care policymakers, taxpayers, and federal hospital beneficiaries benefit from studies that improve hospital efficiency. This study uses data envelopment analysis to evaluate a panel of 165 federal hospitals in 2007 and 157 of the same hospitals again in 2011. Results indicate that overall efficiency in federal hospitals improved from 81% in 2007 to 86% in 2011. The number of federal hospitals operating on the efficiency frontier decreased slightly from 25 in 2007 to 21 in 2011. The higher efficiency score clearly documents that federal hospitals are becoming more efficient in the management of resources. From a policy perspective, this study highlights the economic importance of encouraging increased efficiency throughout the health care industry. This research examines benchmarking strategies to improve the efficiency of hospital services to federal beneficiaries. Through the use of strategies such as integrated information systems, consolidation of services, transaction-cost economics, and focusing on preventative health care, these organizations have been able to provide quality service while maintaining fiscal responsibility. In addition, the research documented the characteristics of those federal hospitals that were found to be on the Efficiency Frontier. These hospitals serve as benchmarks for less efficient federal hospitals as they develop strategies for improvement.

  17. Evaluation of Potential Locations for Siting Small Modular Reactors near Federal Energy Clusters to Support Federal Clean Energy Goals

    Energy Technology Data Exchange (ETDEWEB)

    Belles, Randy J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Omitaomu, Olufemi A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-09-01

    Geographic information systems (GIS) technology was applied to analyze federal energy demand across the contiguous US. Several federal energy clusters were previously identified, including Hampton Roads, Virginia, which was subsequently studied in detail. This study provides an analysis of three additional diverse federal energy clusters. The analysis shows that there are potential sites in various federal energy clusters that could be evaluated further for placement of an integral pressurized-water reactor (iPWR) to support meeting federal clean energy goals.

  18. Federalism, Agenda Setting, and the Dynamics of Federal Education Policy.

    Science.gov (United States)

    Manna, Paul

    This paper is part of a larger project on agenda setting in the U.S. federal system and the development of the federal education agenda since 1965. Two questions motivate the paper, one theoretical and the other empirical: (1) how does federalism affect the federal agenda?; and (2) what explains the development of federal involvement in K-12…

  19. Co-expression of HER3 and MUC1 is associated with a favourable prognosis in patients with bladder cancer

    DEFF Research Database (Denmark)

    Nielsen, Trine O; Borre, Michael; Nexo, Ebba;

    2015-01-01

    OBJECTIVES: To investigate the functional impact of the interaction of MUC1 with the epidermal growth factor receptors HER3 and HER4 in patients with bladder cancer. PATIENTS AND METHODS: Using reverse transcription quantitative polymerase chain reaction, we examined MUC1 expression in 82 bladder...... cancer biopsies previously examined for the expression of HER3. RESULTS: Patients expressing high MUC1 had a favourable survival when the expression of HER3 was also high compared with when the expression of HER3 was low (P = 0.004). When MUC1 expression was low, HER3 co-expression did not influence...... the prognostic value of MUC1 (P = 0.488). MUC1 expression had no correlation with survival, tumour stage or grade, or to the prognostic value of HER4. CONCLUSIONS: A high MUC1 expression was associated with a favourable prognosis in patients with bladder cancer when the expression of HER3 was also high...

  20. 76 FR 37979 - Cooperation in USDA Studies and Evaluations, and Full Use of Federal Funds in Nutrition...

    Science.gov (United States)

    2011-06-29

    ... Service 7 CFR Parts 210, 215, 220, 225, 226, 235, 246, and 248 RIN 0584-AE20 Cooperation in USDA Studies... studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also... Program; the Summer Food Service Program; the Child and Adult Care Food Program; State...

  1. Testing the efficacy of downscaling in species distribution modelling: a comparison between MaxEnt and Favourability Function models

    OpenAIRE

    2016-01-01

    Statistical downscaling is used to improve the knowledge of spatial distributions from broad–scale to fine–scale maps with higher potential for conservation planning. We assessed the effectiveness of downscaling in two commonly used species distribution models: Maximum Entropy (MaxEnt) and the Favourability Function (FF). We used atlas data (10 x 10 km) of the fire salamander Salamandra salamandra distribution in southern Spain to derive models at a 1 x 1 km resolution. Downscaled models were...

  2. Non-fasting triglycerides predict incident acute myocardial infarction among those with favourable HDL-cholesterol: Cohort Norway.

    Science.gov (United States)

    Egeland, Grace M; Igland, Jannicke; Sulo, Gerhard; Nygård, Ottar; Ebbing, Marta; Tell, Grethe S

    2015-07-01

    to prospectively evaluate the risk of acute myocardial infarction (AMI) associated with non-fasting triglyceride levels. a health survey of 140,790 Norwegians free of known coronary heart disease at baseline (1994-2003) were followed through December 2009 via record linkages to the Cause of Death Registry and hospital discharge diagnoses in the CVDNOR project, and evaluated in Cox proportional hazards analyses. a total of 3219 (4.8%) men and 1434 (1.9%) women developed an AMI. Women had a steeper gradient risk with increasing triglyceride decile than men, where the highest (≥2.88 mmol/l) compared to the lowest decile (triglyceride interaction term was observed. HRs increased with increasing triglyceride quartile in participants with a favourable HDL-C after multivariable adjustment (p for trend triglycerides did not significantly predict AMI among those with low HDL-C. For those with favourable HDL-C, net reclassification index identified a 10% and 14% improvement in classification for men and women, respectively. non-fasting triglyceride levels among individuals with favourable HDL-C may help identify a subset of individuals at risk for CHD. Further research is warranted in evaluating non-fasting triglycerides in CHD prediction. © The European Society of Cardiology 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  3. ACA Federal Upper Limits

    Data.gov (United States)

    U.S. Department of Health & Human Services — Affordable Care Act Federal Upper Limits (FUL) based on the weighted average of the most recently reported monthly average manufacturer price (AMP) for...

  4. China Disabled Persons' Federation

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    China Disabled Persons' Federation (CDPF), founded in Beijing in 1988, is a national organization of/for all persons with disabilities (PWDs) of different categories in China. Mr. Deng Pufang is currently the Chairman.

  5. Federal Ballpark Estimator

    Data.gov (United States)

    Office of Personnel Management — The Federal Ballpark E$timate(R) was developed by the Employee Benefit Research Institute(R) and its American Savings Education Council(R) (ASEC(R)) program. It is...

  6. New Mexico Federal Lands

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This map layer consists of federally owned or administered lands of the United States, Puerto Rico, and the U.S. Virgin Islands. Only areas of 640 acres or more are...

  7. Mediastinite no Hospital de Base do Distrito Federal: incidência em seis anos Incidence of mediastinitis at the Hospital de Base do Distrito Federal in six years of study

    Directory of Open Access Journals (Sweden)

    Luiz Carlos SCHIMIN

    2002-06-01

    Full Text Available Realizada análise dos prontuários de pacientes adultos submetidos à operação cardíaca com esternotomia no Hospital de Base do Distrito Federal no período de seis anos. Determinou-se incidência de mediastinite em 15 (1,09% pacientes, dentre 1388 operações cardíacas consecutivas com esternotomia, realizadas no período de janeiro de 1995 e março de 2001. Diversas variáveis foram consideradas, como sexo, idade, tipo de operação, tempo de permanência em respirador, tempo de permanência em Unidade de Terapia Intensiva, uso de antibióticos e germes isolados em culturas de ferida operatória.We review all hospital recorders of the patients that was submitted to cardiac surgery with sternotomy at the Hospital de Base do Distrito Federal in period of six years. Fifteen patients (1.09% developed mediastinitis in this period in a total of 1388 cardiac surgeries between January 1995 and March 2001. Sex, age, type of surgery, respirator time, ICU permanence, use of antibiotics and type of bacteria isolated were some variables analyzed.

  8. Employees’ Participation in Decision Making and the Hospitality Industry in Nigeria. An Investigative Study of Selected Hotels in the Federal Capital Territory, Abuja, Nigeria

    Directory of Open Access Journals (Sweden)

    Isichei Ejikeme Emmanuel

    2015-12-01

    Full Text Available The study investigated employee’s participation in decision making and the hospitality industry in Nigeria, a study of selected hotels in the federal capital territory in Abuja. To guide the study, research questions and hypotheses were designed. An in-depth review of related literature was carried out. Primary data method was used for the study and the instrument used was a questionnaire survey designed using the Likert scale questionnaire format and administered to sixty respondents. Test of reliability of research instrument showed a result of .874 using Cronbach Alpha. Content method was used for validity of the research instrument. Two Hypotheses was postulated in line with the objectives and research question to test the significance of the research problems. The study used linear correlation and regression for analysis of data obtained from research instrument, which proved the alternate hypothesis significant in the two hypotheses tested. Findings in the study showed that employee’s participation in decision making impacts on the performance of hotels in Nigeria. The study concludes there is a positive relationship between extent of employee’s participation in decision making and organisational performance. The study recommends among others that participation of employees’ should not just be partial but holistic to give them a sense of belonging.

  9. Integrated vs. Federated Search

    DEFF Research Database (Denmark)

    Løvschall, Kasper

    2009-01-01

    Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009.......Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009....

  10. Foliar photochemical processes and carbon metabolism under favourable and adverse winter conditions in a Mediterranean mixed forest, Catalonia (Spain

    Directory of Open Access Journals (Sweden)

    D. Sperlich

    2014-06-01

    Full Text Available Evergreen trees in the Mediterranean region must cope with a wide range of environmental stresses from summer drought to winter cold. The mildness of Mediterranean winters can periodically lead to favourable environmental conditions above the threshold for a positive carbon balance, benefitting evergreen woody species more than deciduous ones. The comparatively lower solar energy input in winter decreases the foliar light saturation point. This leads to a higher susceptibility to photoinhibitory stress especially when chilly (Quercus ilex L., Pinus halepensis Mill., and Arbutus unedo L. during a period of mild winter conditions and their responses to a sudden cold period. The state of the photosynthetic machinery in both periods was thus tested by estimating the foliar photosynthetic potential with CO2 response curves in parallel with chlorophyll fluorescence measurements. The studied evergreen tree species benefited strongly from mild winter conditions by exhibiting extraordinarily high photosynthetic potentials similar to those under spring conditions. A sudden period of frost, however, negatively affected the photosynthetic apparatus, leading to significant decreases in key physiological parameters such as the maximum carboxylation velocity (Vc, max, the maximum photosynthetic electron transport rate (Jmax, and the optimal fluorometric quantum yield of photosystem II (Fv/Fm. This change persisted for several weeks after the cold period despite the recovery of the temperature to the conditions previous to the frost event. The responses of Vc, max and Jmax were highly species-specific, where Q. ilex exhibited the highest and P. halepensis the lowest reductions. In contrast, the optimal fluorometric quantum yield of photosystem II (Fv/Fm was significantly lower in A. unedo after the cold period. The leaf position played an important role in Q. ilex showing a comparatively stronger winter effect on sunlit leaves. Our results generally agreed with

  11. Oil Federalism In Iraq: Resource Curse, Patronage Networks and Stability. Case Studies of Baghdad, Kurdistan and the Advent of ISIS

    Science.gov (United States)

    Wahab, Bilal A.

    Petroleum wealth is the lifeblood of Iraq, with the potential to promote prosperity, or become a curse that destabilizes the country and interrupts its economic and political development. The management and sharing of petroleum wealth has been at the center of economic, political and security developments in Iraq since the country's invasion in 2003. This study analyzes Iraq's experiment with petrofederalism, the influence of different actors (e.g. international oil companies and ISIS), and the emergence of Iraqi Kurdistan as a petroregion. Using case study method, it demonstrates how patronage politics exacerbated resource curse in Iraq and resulted in instability.

  12. A prospective, open-label, non-comparative study of palivizumab prophylaxis in children at high risk of serious respiratory syncytial virus disease in the Russian Federation

    Directory of Open Access Journals (Sweden)

    Turti Tatyana V

    2012-09-01

    Full Text Available Abstract Background Respiratory syncytial virus (RSV is a leading cause of lower respiratory tract infections (LRTIs in children globally. Predisposing conditions for the development of serious RSV disease include preterm infants and those with cardiopulmonary illness, including congenital heart disease (CHD and bronchopulmonary dysplasia (BPD. No vaccine is currently approved for the prevention of RSV infection. It is recommended that children at high risk be prophylactically administered palivizumab, a monoclonal antibody that has been shown in a number of clinical studies to reduce hospitalization rates due to serious RSV infection. The objective of the current study was to determine the safety and effectiveness of palivizumab in preventing serious RSV disease in high-risk children in the Russian Federation. Children at high risk of serious RSV disease (ie, born at ≤35 wk gestational age and ≤6 mo of age, and/or aged ≤24 mo with BPD or hemodynamically significant CHD were enrolled. Subjects were to receive 3 to 5 monthly injections of palivizumab 15 mg/kg (depending on the month of the initial injection over the RSV season. The primary endpoint was RSV-related hospitalizations. Adverse events (AEs were reported through 100 days following the final injection. Results One hundred subjects received ≥1 injection of palivizumab; 94 completed their dosing schedule. There were no RSV hospitalizations or deaths. Six of 7 subjects hospitalized for respiratory/cardiac conditions had an RSV test, which was negative in all cases. Three non-serious AEs (acute intermittent rhinitis and rhinitis, 1 subject; atopic dermatitis, 1 subject were considered possibly related to palivizumab. All other AEs were mild or moderate and considered not related/probably not related to palivizumab. Conclusion Palivizumab was generally well tolerated and effectively prevented serious RSV infection in a mixed population of high-risk children in the Russian

  13. The Current Mind-Set of Federal Information Security Decision-Makers on the Value of Governance: An Informative Study

    Science.gov (United States)

    Stroup, Jay Walter

    2014-01-01

    Understanding the mind-set or perceptions of organizational leaders and decision-makers is important to ascertaining the trends and priorities in policy and governance of the organization. This study finds that a significant shift in the mind-set of government IT and information security leaders has started and will likely result in placing a…

  14. [Teacher development and post-graduate studies in health: an experience at the Federal University of São Paulo].

    Science.gov (United States)

    Freitas, Maria Aparecida de Oliveira; Seiffert, Otilia Maria Lúcia Barbosa

    2007-01-01

    The aim of this study was to analyze the views and conceptions shared by the graduate students who attended the Pedagogy and Didactics in Health Sciences Course, offered by the Graduate Programs at the UNIFESP. The methodological approach consisted of bibliographic research on the higher education teaching; documental analysis involving the national legislation for higher education, teaching and graduate studies and documents related to this Course. Graduate students from 1998 and 2003 were mapped in order to build the samples of those (112 egresses) that were involved in teaching activities. The data were collected through a semi-structured questionnaire. The data analysis, oriented by the Content Analysis Technique, reveals that this experience has an influence on the way these professors understand and practice their teaching skills, showing the importance for the faculty development at the higher education level in Health Sciences.

  15. Why Are Employees Leaving the Federal Government? Results of an Exit Survey. A Report to the President and the Congress of the United States. A Special Study.

    Science.gov (United States)

    Merit Systems Protection Board, Washington, DC.

    The success of virtually every endeavor of the Federal Government depends on the skills, abilities, and motivations of its work force. Yet recent years have seen increasing concern about the quality of the Federal work force and the Government's ability to retain its most capable employees. In any given year, the Government loses nearly 120,000…

  16. Foliar photochemical processes and carbon metabolism under favourable and adverse winter conditions in a Mediterranean mixed forest, Catalonia (Spain)

    Science.gov (United States)

    Sperlich, D.; Chang, C. T.; Peñuelas, J.; Gracia, C.; Sabaté, S.

    2014-10-01

    Evergreen trees in the Mediterranean region must cope with a wide range of environmental stresses from summer drought to winter cold. The mildness of Mediterranean winters can periodically lead to favourable environmental conditions above the threshold for a positive carbon balance, benefitting evergreen woody species more than deciduous ones. The comparatively lower solar energy input in winter decreases the foliar light saturation point. This leads to a higher susceptibility to photoinhibitory stress especially when chilly (compensates for the lower carbon uptake during spring and summer in comparison to deciduous species. We investigated the ecophysiological behaviour of three co-occurring mature evergreen tree species (Quercus ilex L., Pinus halepensis Mill., and Arbutus unedo L.). Therefore, we collected twigs from the field during a period of mild winter conditions and after a sudden cold period. After both periods, the state of the photosynthetic machinery was tested in the laboratory by estimating the foliar photosynthetic potential with CO2 response curves in parallel with chlorophyll fluorescence measurements. The studied evergreen tree species benefited strongly from mild winter conditions by exhibiting extraordinarily high photosynthetic potentials. A sudden period of frost, however, negatively affected the photosynthetic apparatus, leading to significant decreases in key physiological parameters such as the maximum carboxylation velocity (Vc, max), the maximum photosynthetic electron transport rate (Jmax), and the optimal fluorometric quantum yield of photosystem II (Fv/Fm). The responses of Vc, max and Jmax were highly species specific, with Q. ilex exhibiting the highest and P. halepensis the lowest reductions. In contrast, the optimal fluorometric quantum yield of photosystem II (Fv/Fm) was significantly lower in A. unedo after the cold period. The leaf position played an important role in Q. ilex showing a stronger winter effect on sunlit leaves in

  17. 75 FR 29744 - Federal Pell Grant, Federal Perkins Loan, Federal Work-Study, Federal Supplemental Educational...

    Science.gov (United States)

    2010-05-27

    ... for general price inflation. The changes are based, in general, upon increases in the Consumer Price... must be based upon a percentage equal to the estimated percentage increase in the Consumer Price Index... schedules and rates to account for inflation that took place between December 2009 and December 2010...

  18. Factors influencing the adoption of a healthy eating campaign by federal cross-sector partners: a qualitative study.

    Science.gov (United States)

    Fernandez, Melissa Anne; Desroches, Sophie; Turcotte, Mylène; Marquis, Marie; Dufour, Joëlle; Provencher, Véronique

    2016-08-30

    The Eat Well Campaign (EWC) was a social marketing campaign developed by Health Canada and disseminated to the public with the help of cross-sector partners. The purpose of this study was to describe factors that influenced cross-sector partners' decision to adopt the EWC. Thematic content analysis, based primarily on an a priori codebook of constructs from Roger's diffusion of innovations decision process model, was conducted on hour-long semi-structured telephone interviews with Health Canada's cross-sector partners (n = 18). Dominant themes influencing cross-sector partners' decision to adopt the EWC were: high compatibility with the organization's values; being associated with Health Canada; and low perceived complexity of activities. Several adopters indicated that social norms (e.g., knowing that other organizations in their network were involved in the collaboration) played a strong role in their decision to participate, particularly for food retailers and small organizations. The opportunity itself to work in partnership with Health Canada and other organizations was seen as a prominent relative advantage by many organizations. Adopters were characterized as having high social participation and positive attitudes towards health, new ideas and Health Canada. The lack of exposure to the mass media channels used to diffuse the campaign and reserved attitudes towards Health Canada were prominent obstacles identified by a minority of health organizations, which challenged the decision to adopt the EWC. Most other barriers were considered as minor challenges and did not appear to impede the adoption process. Understanding factors that influence cross-sector adoption of nutrition initiatives can help decision makers target the most appropriate partners to advance public health objectives. Government health agencies are likely to find strong partners in organizations that share the same values as the initiative, have positive attitudes towards health, are

  19. Farming systems in two less favoured areas in portugal: their development from 1989 to 2009 and the implications for sustainable land management

    NARCIS (Netherlands)

    Jones, N.M.; Graaff, de J.; Duarte, F.; Rodrigo, I.; Poortinga, A.

    2014-01-01

    Since the late 1980s, sustainable land management is one of the objectives of the European Commission in Less Favoured Areas. In this paper, we investigate the economic and environmental sustainability of farming systems in two less favoured areas in Centro and Alentejo areas of Portugal. The specif

  20. Oil and gas impacts on air quality in federal lands in the Bakken region: an overview of the Bakken Air Quality Study and first results

    Science.gov (United States)

    Prenni, A. J.; Day, D. E.; Evanoski-Cole, A. R.; Sive, B. C.; Hecobian, A.; Zhou, Y.; Gebhart, K. A.; Hand, J. L.; Sullivan, A. P.; Li, Y.; Schurman, M. I.; Desyaterik, Y.; Malm, W. C.; Collett, J. L., Jr.; Schichtel, B. A.

    2016-02-01

    The Bakken formation contains billions of barrels of oil and gas trapped in rock and shale. Horizontal drilling and hydraulic fracturing methods have allowed for extraction of these resources, leading to exponential growth of oil production in the region over the past decade. Along with this development has come an increase in associated emissions to the atmosphere. Concern about potential impacts of these emissions on federal lands in the region prompted the National Park Service to sponsor the Bakken Air Quality Study over two winters in 2013-2014. Here we provide an overview of the study and present some initial results aimed at better understanding the impact of local oil and gas emissions on regional air quality. Data from the study, along with long-term monitoring data, suggest that while power plants are still an important emissions source in the region, emissions from oil and gas activities are impacting ambient concentrations of nitrogen oxides and black carbon and may dominate recent observed trends in pollutant concentrations at some of the study sites. Measurements of volatile organic compounds also definitively show that oil and gas emissions were present in almost every air mass sampled over a period of more than 4 months.

  1. Oil and gas impacts on air quality in federal lands in the Bakken region: an overview of the Bakken Air Quality Study and first results

    Directory of Open Access Journals (Sweden)

    A. J. Prenni

    2015-10-01

    Full Text Available The Bakken formation contains billions of barrels of oil and gas trapped in rock and shale. Horizontal drilling and hydraulic fracturing methods have allowed for extraction of these resources, leading to exponential growth of oil production in the region over the past decade. Along with this development has come an increase in associated emissions to the atmosphere. Concern about potential impacts of these emissions on federal lands in the region prompted the National Park Service to sponsor the Bakken Air Quality Study over two winters in 2013–2014. Here we provide an overview of the study and present some initial results aimed at better understanding the impact of local oil and gas emissions on regional air quality. Data from the study, along with long term monitoring data, suggest that while power plants are still an important emissions source in the region, emissions from oil and gas activities are impacting ambient concentrations of nitrogen oxides and black carbon and may dominate recent observed trends in pollutant concentrations at some of the study sites. Measurements of volatile organic compounds also definitively show that oil and gas emissions were present in almost every air mass sampled over a period of more than four months.

  2. Federalism and Health Care

    Directory of Open Access Journals (Sweden)

    G. Alan Tarr

    2011-10-01

    Full Text Available President Barack Obama proposed a major overhaul of the American healthsystem, and in 2010 the U.S. Congress enacted his proposal, the PatientProtection and Affordable Care Act. Opponents of the Act challenged itsconstitutionality in federal court, claiming that it exceeds the powers grantedto the federal government under the Commerce Clause and the NecessaryProper Clause of the federal Constitution. Some courts have upheldthe law, but others have agreed with the critics, in particular ruling thatthe provision requiring citizens to buy health insurance is unconstitutional.Eventually the U.S. Supreme Court will rule on the issue. This article tracesthe controversy, surveys the interpretation of pertinent constitutional provisionsin past cases, analyzes the constitutional arguments presented byproponents and opponents of the Act, and concludes that the Act is constitutional.

  3. Social media in times of libraries 2.0: A study into the Brazilian Federal Education instituitions’ libraries bringing future perspectives for digital preservation

    Directory of Open Access Journals (Sweden)

    Laura Vilela Rodriges Rezende

    2016-09-01

    Full Text Available This study aims to discuss the main challenges regarding the social participation on the Web by the Brazilian Federal Education Institutions’(IFES Libraries and the changes related to the these institutions’ activities, especially interactions with their audience. The Research conducted a quantitative approach survey on the use of the main existing social media by these libraries. The survey sought to identify the level of involvement and participation of these libraries in social media. It is understood that this investigation is necessary as a foundation to the urgent need to raise awareness these Brazilian institutions as the valuable potential of interaction with their users through these media, despite the study demonstrated an incipient use. Based on the conducted survey, the study presents a reflection of the importance that it should devote to digital preservation, not only of their collections, but also the relevant records of the social media content. The results show that most brazilian public universities use Web 2.0 tools with social focus, and the greater adoption of Facebook (43% and Twitter (29%, but only 5% of them use these medias to disseminate the collections. Thus, it was concluded that the use of social media by these libraries still have a lot to develop and consequently the digital preservation actions need to consider the inclusion of content generated by these media that increasingly have become a valuable communication channel.

  4. Federalism and health policy.

    Science.gov (United States)

    Nathan, Richard P

    2005-01-01

    This paper presents a cyclical theory of U.S. federalism and social policy: Many social policy initiatives are tested and refined at the state level, especially during conservative periods, and later morph into national policies. The paper describes such federalism cycles and offers an interpretation of why and how they occur, focusing on Medicaid. State activism has preserved and expanded Medicaid through policy innovation and resistance to retrenchment, especially in conservative periods, by taking advantage of the flexibility the program provides. I conclude that Medicaid's incremental/partnership approach is appropriate and feasible to build on for a future expansion of health care coverage.

  5. Federative competence conflicts in the natural gas sector distribution; Conflitos de competencias federativas no ambito da distribuicao do gas natural

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Adriano; Nunes, Alessandro; Nascimento, Juliana; Gois, Luciana; Jardim, Mariana; Moura, Tacio; Campos, Vitor [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Faculdade de Direito

    2004-07-01

    This essay intends to broach the role played by the federative agents in the natural gas distribution regulation and analyses the conflict arisen from the new script of the article 25, para. 2nd of the Constitution, given by the amendment 5/95. For this, it is necessary to make a brief expose of the different types of non-tributary federative scope distribution and also to talk over about the natural problems from the lack of a clear appraisal of what canalized gas is, defining the state jurisdiction's object. Only then, it is possible to analyse its limits on the canalized gas local services distribution. In this context, it is evident that the role played by the state regulatory agent in promoting a favourable environment to the competition searching for alternatives concerning the problems of the natural monopoly. Equally important, is the study case of Amazonas, in which is enlightened the position of certain agencies and state agents when their constitutional sphere of influence is extrapolated. For the reasons exposed, it is imperative to improve the current forensic model to guarantee a more effective Union participation, at least to assure a minimum level of regulatory uniformization among the federative states. (author)

  6. MANAGEMENT ACCOUNTING SYSTEM OF PUBLIC OFF-BUDGET FUNDS AS AN INFORMATIONAL BASIS FOR PUBLIC INSURANCE MECHANISMS FORMATION (CASE STUDY OF FEDERAL COMPULSORY MEDICAL INSURANCE FUND)

    OpenAIRE

    Anatoly A. Kozlov

    2014-01-01

    The article justifies the introduced proposals for a management accounting of theFederal Compulsory Medical InsuranceFund formation and the characteristics and principles of management accounting forms for the analysis of the territorialcompulsory medical insurance programs.

  7. Coronary computed tomography angiography without significant stenosis predicts favourable three-year prognosis

    DEFF Research Database (Denmark)

    Kristiansen, Jeppe Maagaard; Zaremba, Tomas; Johansen, Martin Berg

    2014-01-01

    INTRODUCTION: The objective of this study was to evaluate the incidence of death, cardiovascular events and the use of later non-scheduled imaging for coronary artery disease (CAD) in patients suspected for CAD and discharged without a need for further examination or treatment from an outpatient...... clinic following coronary computed tomography angiography (CCTA). MATERIAL AND METHODS: This was a retrospective cohort study among patients discharged from an outpatient clinic after CCTA at our institution during 2009 and 2010. Follow-up was performed using nationwide Danish registers. RESULTS: A total...... of acute myocardial infarction and no cases of death related to cardiovascular disease. A total of 5.0% of the patients later underwent non-scheduled imaging, predominantly invasive coronary angiography. No patients had revascularisation performed during the study period. CONCLUSION: Patients...

  8. Dog-associated husbandry practices favouring the spread of zoonotic pathogens with reference to helminth and arthropod parasites in Yaounde, Cameroon

    Directory of Open Access Journals (Sweden)

    N jong

    2012-11-01

    Full Text Available Dogs are the most common animal species kept around households and are also known to be source of diseases of importance to human health. The aim of this study was to determine some characteristics of dog population and husbandry practices that favour the spread of zoonotic parasites in Yaounde, Cameroon. Three hundred and twenty-two households owning at least one dog were recruited into the study. Information on dog and household characteristics as well as potential risk factors for the transmission of dog-related zoonotic parasites was collected using self-administered questionnaires. Over three-quarters of the households (76% owned one dog each while 62% (200/322 kept dogs strictly for security reasons. Eighty four per cent (270/322 of the dogs owned were of local breed type and dominated by male dogs (64%. Twenty five per cent (80/320 of households left their dogs permanently free while 84% (240/320 declared negligence in disposing dog’s faeces. Dogs in 35.5% (114/320 of the households rarely or have never been consulted by a veterinarian. Although 242 (75% respondents were aware of zoonotic diseases, only 51 (21% of these knew parasites from dogs may infect human beings. The provision of a defecation site for dogs and access to living quarters were associated with household head’s level of education and care taker category, respectively. The current dog husbandry practices in Yaounde are likely to favour the spread of dog-related zoonotic diseases. Further investigations to determine the prevalence of zoonotic parasites, educational intervention as well as routine veterinary care are necessary to reduce the risk exposures to zoonotic parasites from dogs.  

  9. Federal R&D Funding Shows Strong Recent Rise But Little Real Growth in FY 1978. Science Resources Studies Highlights, October 17, 1977.

    Science.gov (United States)

    National Science Foundation, Washington, DC. Div. of Science Resources Studies.

    This document reports results of a review of estimated 1977 federal research and development (R&D) funding and requested 1978 federal R&D funding. Highlights include: 1978 estimated R&D total is $26.3 billion, an increase of 7.6% over 1977; average annual R&D growth rate for the period 1974-78 has risen to 10.9% compared to 1.5%…

  10. Coronary computed tomography angiography without significant stenosis predicts favourable three-year prognosis

    DEFF Research Database (Denmark)

    Kristiansen, Jeppe Maagaard; Zaremba, Tomas; Johansen, Martin Berg;

    2014-01-01

    INTRODUCTION: The objective of this study was to evaluate the incidence of death, cardiovascular events and the use of later non-scheduled imaging for coronary artery disease (CAD) in patients suspected for CAD and discharged without a need for further examination or treatment from an outpatient...... of acute myocardial infarction and no cases of death related to cardiovascular disease. A total of 5.0% of the patients later underwent non-scheduled imaging, predominantly invasive coronary angiography. No patients had revascularisation performed during the study period. CONCLUSION: Patients...

  11. Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels

    NARCIS (Netherlands)

    Kubben, F.J.G.M.; Sier, C.F.M.; Schram, M.; Witte, T.A.M.C.; Veenendaal, R.A.; Duijn, W. van; Verheijen, J.H.; Hanemaaijer, R.; Lamers, C.B.H.W.; Verspaget, H.W.

    2007-01-01

    Background: Helicobacter pylori gastritis is recognized as an important pathogenetic factor in peptic ulcer disease and gastric carcinogenesis, and is accompanied by strongly enhanced gastric mucosal matrix metalloproteinase-9 (MMP-9) levels. Aim: This study was performed to investigate whether H.

  12. Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels

    NARCIS (Netherlands)

    Kubben, F.J.G.M.; Sier, C.F.M.; Schram, M.; Witte, T.A.M.C.; Veenendaal, R.A.; Duijn, W. van; Verheijen, J.H.; Hanemaaijer, R.; Lamers, C.B.H.W.; Verspaget, H.W.

    2007-01-01

    Background: Helicobacter pylori gastritis is recognized as an important pathogenetic factor in peptic ulcer disease and gastric carcinogenesis, and is accompanied by strongly enhanced gastric mucosal matrix metalloproteinase-9 (MMP-9) levels. Aim: This study was performed to investigate whether H. p

  13. Energy policy and federalism

    Energy Technology Data Exchange (ETDEWEB)

    Thur, L.M. (ed.)

    1981-04-01

    Separate abstracts are prepared for six papers presented as the product of an international seminar on Energy Policy and Federalism in North America. Specially commissioned papers for the seminar are presented along with a summary of the discussions. The summary appears in English, French, and Spanish; the other papers are in English. (MCW)

  14. Federal Forecasters Directory, 1995.

    Science.gov (United States)

    National Center for Education Statistics (ED), Washington, DC.

    This directory lists employees of the federal government who are involved in forecasting for policy formation and trend prediction purposes. Job title, agency, business address, phone or e-mail number, and specialty areas are listed for each employee. Employees are listed for the following agencies: (1) Bureau of the Census; (2) Bureau of Economic…

  15. Future Federal Role.

    Science.gov (United States)

    USA Today, 1982

    1982-01-01

    Reviews comments by United States Secretary of Education Terrel H. Bell about the future federal role in higher education. The role will be confined to student financial aid and support for research. Bell's statements about the quality of higher education are also included. (SR)

  16. Federal budget timetable

    Science.gov (United States)

    This is the federal budget timetable under the Balanced Budget and Emergency Deficit Control Act of 1985 (Gramm-Rudman-Hollings). These deadlines apply to fiscal years (FY) 1987-1991. The deficit reduction measures in Gramm-Rudman-Hollings would lead to a balanced budget in 1991.

  17. Sexual antagonism and meiotic drive cause stable linkage disequilibrium and favour reduced recombination on the X chromosome.

    Science.gov (United States)

    Rydzewski, W T; Carioscia, S A; Liévano, G; Lynch, V D; Patten, M M

    2016-06-01

    Sexual antagonism and meiotic drive are sex-specific evolutionary forces with the potential to shape genomic architecture. Previous theory has found that pairing two sexually antagonistic loci or combining sexual antagonism with meiotic drive at linked autosomal loci augments genetic variation, produces stable linkage disequilibrium (LD) and favours reduced recombination. However, the influence of these two forces has not been examined on the X chromosome, which is thought to be enriched for sexual antagonism and meiotic drive. We investigate the evolution of the X chromosome under both sexual antagonism and meiotic drive with two models: in one, both loci experience sexual antagonism; in the other, we pair a meiotic drive locus with a sexually antagonistic locus. We find that LD arises between the two loci in both models, even when the two loci freely recombine in females and that driving haplotypes will be enriched for male-beneficial alleles, further skewing sex ratios in these populations. We introduce a new measure of LD, Dz', which accounts for population allele frequencies and is appropriate for instances where these are sex specific. Both models demonstrate that natural selection favours modifiers that reduce the recombination rate. These results inform observed patterns of congealment found on driving X chromosomes and have implications for patterns of natural variation and the evolution of recombination rates on the X chromosome.

  18. Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination

    Directory of Open Access Journals (Sweden)

    Jansen Frans

    2011-03-01

    Full Text Available Abstract Recent publications put a serious warning regarding the inefficacy of sulphadoxine-pyrimethamine (SP for the intermittent preventive treatment of malaria in young children (IPTi. Recommendations for other therapies are being made. By using a different and better sulphonamide (sulphamethoxypyrazine, it is possible to manufacture fixed dose combination pills with artesunate and pyrimethamine. This combination permits a full therapy over 24 hours (dosing interval being 12 hours. It is recommended that this combination should be tested in future field studies of IPTi.

  19. Goats favour personal over social information in an experimental foraging task

    Directory of Open Access Journals (Sweden)

    Luigi Baciadonna

    2013-09-01

    Full Text Available Animals can use their environments more efficiently by selecting particular sources of information (personal or social, according to specific situations. Group-living animals may benefit from gaining information based on the behaviour of other individuals. Indeed, social information is assumed to be faster and less costly to use than personal information, thus increasing foraging efficiency. However, when food sources change seasonally or are randomly distributed, individual information may become more reliable than social information. The aim of this study was to test the use of conflicting personal versus social information in goats (Capra hircus, in a foraging task. We found that goats relied more on personal than social information, when both types of information were available and in conflict. No effect of social rank was found on the occasions when goats followed other demonstrator goats. Goats are selective browsers/grazers and therefore relying on personal rather than social information could be the most efficient way to find patchily distributed resources in highly variable environments. Studies testing specific assumptions regarding the use of different sources of information can extend our understanding of decision making, including observed patterns of social learning.

  20. Goats favour personal over social information in an experimental foraging task.

    Science.gov (United States)

    Baciadonna, Luigi; McElligott, Alan G; Briefer, Elodie F

    2013-01-01

    Animals can use their environments more efficiently by selecting particular sources of information (personal or social), according to specific situations. Group-living animals may benefit from gaining information based on the behaviour of other individuals. Indeed, social information is assumed to be faster and less costly to use than personal information, thus increasing foraging efficiency. However, when food sources change seasonally or are randomly distributed, individual information may become more reliable than social information. The aim of this study was to test the use of conflicting personal versus social information in goats (Capra hircus), in a foraging task. We found that goats relied more on personal than social information, when both types of information were available and in conflict. No effect of social rank was found on the occasions when goats followed other demonstrator goats. Goats are selective browsers/grazers and therefore relying on personal rather than social information could be the most efficient way to find patchily distributed resources in highly variable environments. Studies testing specific assumptions regarding the use of different sources of information can extend our understanding of decision making, including observed patterns of social learning.

  1. Biodeterioration of Pompeian mural paintings: fungal colonization favoured by the presence of volcanic material residues.

    Science.gov (United States)

    Veneranda, Marco; Prieto-Taboada, Nagore; de Vallejuelo, Silvia Fdez-Ortiz; Maguregui, Maite; Morillas, Hector; Marcaida, Iker; Castro, Kepa; Madariaga, Juan Manuel; Osanna, Massimo

    2017-07-05

    This work was focused on the study of the biodegradation processes jeopardizing a mural painting conserved in the basement of Ariadne House (archaeological site of Pompeii, Italy). The fresco stood out for its peculiar state of preservation: the upper part, recovered in 1988, was just barely colonized by microorganisms. On the contrary, the lower part (excavated in 2005) was almost completely covered by extensive biological patinas. The genomic characterization carried out by polymerase chain reaction (PCR) highlighted the presence of seven different fungi strains on the mural surface. Beside, in situ and laboratory analyses were performed with the purpose of identifying the causes of the heterogeneous spatial distribution of the biopatinas. The in situ Raman spectroscopy and energy dispersive X-ray fluorescence (ED-XRF) spectroscopy measurements excluded any link between the heterogeneous colonization and the original materials present in the wall. On the other side, X-ray diffraction (XRD) and scanning electron microscopy (SEM) on microsamples proved the presence of a thin volcanic material layer overlying the lower part of the fresco. Considering that most of the biofilms of the studied mural painting only growth over these residues, it was confirmed the role of volcanic material as a suitable support for biological colonization. Thanks to the obtained results, this research helped to understand more in depth an important degradation pathway threatening the artworks from one of the most important archaeological sites in the world.

  2. The natural antioxidants, pomegranate extract and soy isoflavones, favourably modulate canine endothelial cell function.

    Science.gov (United States)

    Baumgartner-Parzer, Sabina M; Waldenberger, Ferdinand Rudolf; Freudenthaler, Angelika; Ginouvès-Guerdoux, Amandine; McGahie, David; Gatto, Hugues

    2012-01-01

    Cardiovascular disease, preceded by vascular endothelial dysfunction, is a prominent cause of death in dogs. L-carnitine and taurine, well known for their antioxidative capacity, beneficially affect cardiovascular disease as well as certain dog cardiomyopathies. It is well established that vascular endothelial dysfunction precedes cardiovascular disease and that "vasoprotective factors" (NO and antioxidants) prevent apoptosis, whereas "risk factors" such as oxidized LDL, hyperglycemia, and free fatty acids trigger it in cultured human vascular endothelial cells. Whereas human vascular cell in vitro models are widely established and used for the characterisation of potential vasoprotective substances, such models are not available for canine endothelial cells. In the present study we therefore developed an in vitro model, which allows the testing of the effects of different substances on proliferation and apoptosis in canine aortic endothelial cells. This model was used to test L-carnitine, taurine, pomegranate extract, and Soy Isoflavones in comparison to reference substances (glutathione and pioglitazone) previously shown to modulate human endothelial cell function. L-carnitine and taurine neither exhibited antiproliferative nor antiapoptotic activities in the context of this study. However extracts from pomegranate and soy isoflavones dramatically reduced proliferation and apoptosis in a dose dependent fashion, being in line with a vasoprotective activity in dogs.

  3. Clinical heterogeneity among people with high functioning autism spectrum conditions: evidence favouring a continuous severity gradient

    Directory of Open Access Journals (Sweden)

    Woodbury-Smith Marc

    2008-02-01

    Full Text Available Abstract Background Autism Spectrum Conditions (ASCs are characterized by a high degree of clinical heterogeneity, but the extent to which this variation represents a severity gradient versus discrete phenotypes is unclear. This issue has complicated genetic studies seeking to investigate the genetic basis of the high hereditability observed clinically in those with an ASC. The aim of this study was to examine the possible clustering of symptoms associated with ASCs to determine whether the observed distribution of symptom type and severity supported either a severity or a symptom subgroup model to account for the phenotypic variation observed within the ASCs. Methods We investigated the responses of a group of adults with higher functioning ASCs on the fifty clinical features examined in the Autism Spectrum Quotient, a screening questionnaire used in the diagnosis of higher functioning ASCs. In contrast to previous studies we have used this instrument with no a priori assumptions about any underlying factor structure of constituent items. The responses obtained were analyzed using complete linkage hierarchical cluster analysis. For the members of each cluster identified the mean score on each Autism Spectrum Quotient question was calculated. Results Autism Spectrum Quotient responses from a total of 333 individuals between the ages of 16.6 and 78.0 years were entered into the hierarchical cluster analysis. The four cluster solution was the one that generated the largest number of clusters that did not also include very small cluster sizes, defined as a membership comprising 10 individuals or fewer. Examination of these clusters demonstrated that they varied in total Autism Spectrum Quotient but that the profiles across the symptoms comprising the Autism Spectrum Quotient did not differ independently of this severity factor. Conclusion These results are consistent with a unitary spectrum model, suggesting that the clinical heterogeneity observed

  4. Aspergillus spp. invasive external otitis: favourable outcome with a medical approach.

    Science.gov (United States)

    Marchionni, E; Parize, P; Lefevre, A; Vironneau, P; Bougnoux, M E; Poiree, S; Coignard-Biehler, H; DeWolf, S E; Amazzough, K; Barchiesi, F; Jullien, V; Alanio, A; Garcia-Hermoso, D; Wassef, M; Kania, R; Lortholary, O; Lanternier, F

    2016-05-01

    Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was Aspergillus flavus (n = 10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days (158-804 days). None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otological sequelae were reported, including hearing impairment (n = 7) and facial palsy (n = 3).

  5. Evidence for maternally inherited factors favouring male homosexuality and promoting female fecundity.

    Science.gov (United States)

    Camperio-Ciani, Andrea; Corna, Francesca; Capiluppi, Claudio

    2004-11-07

    The Darwinian paradox of male homosexuality in humans is examined, i.e. if male homosexuality has a genetic component and homosexuals reproduce less than heterosexuals, then why is this trait maintained in the population? In a sample of 98 homosexual and 100 heterosexual men and their relatives (a total of over 4600 individuals), we found that female maternal relatives of homosexuals have higher fecundity than female maternal relatives of heterosexuals and that this difference is not found in female paternal relatives. The study confirms previous reports, in particular that homosexuals have more maternal than paternal male homosexual relatives, that homosexual males are more often later-born than first-born and that they have more older brothers than older sisters. We discuss the findings and their implications for current research on male homosexuality.

  6. Development of a methodology for dissemination and formation favourable of using nuclear energy

    Energy Technology Data Exchange (ETDEWEB)

    Lobo, Belinda Maria; Aquino, Afonso Rodrigues de, E-mail: belindalobo@usp.br, E-mail: araquino@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    Space Nuclear Technology (ENT), located in the IPEN is the basis for the study of a reporting methodology of Nuclear Energy Technology, for the public get some physical-chemical knowledge, benefits of using radioactivity and the activities carried out by the Institute Energy and Nuclear Research - National Commission of Nuclear Energy (IPEN / CNEN), for increased acceptance of its use. This article reports the survey in two schools, with groups of teachers from different areas of elementary and secondary education of the Sao Paulo state. The strategies used to establish communication by means of an environment of trust are: a questionnaire at the beginning and end of the presentation, one sensationalised reporting, Cesium -137 -Linha Direta, aired by Rede Globo TV, in 2007, theoretical foundation of physics and chemistry, picturesque figures and photos as the Nuclear Reactor IEA-R1. The contributions of this research will improve the methodology for future presentations. (author)

  7. [Systemic Antimicrobials Consumption and Expenditures in Departments of Surgery of Multi-Profile Hospitals in the Russian Federation and the Republic of Belarus: Results of Multicentre Pharmacoepidemiological Study].

    Science.gov (United States)

    Belkova, Yu A; Rachina, S A; Kozlov, R S; Mishchenko, V M; Pavlukov, R A; Abubakirova, A I; Berezhanskiy, B V; Eliseeva, E V; Zubareva, N A; Karpov, I A; Kopylova, I A; Palyutin, Sh Kh; Portnyagina, U S; Pribytkova, O V; Samuylo, E K

    2016-01-01

    The results of the systemic antimicrobials (AM) consumption and expenditures assessment in the departments of surgery of multi-profile hospitals in different regions of the Russian Federation and the Republic of Belarus in 2009-2010 based on retrospective collection and analysis of the data from the hospital expenditure notes using ATC/DDD methodology are presented. The average AM consumption and expenditure rates in the above mentioned departments varied from 24.9 DDD/100 bed-days to 61.7 DDD/100 bed-days depending on the department profile, with beta-lactams (cephalosporins and penicillins) share in the consumption being as high as 70-90%, followed by fluoroquinolones and aminoglycosides. Only 55-70% of the consumed AM belonged to the drugs of choice, whereas the improper AM consumption and expenditure rates amounted up to 10-18%. The study outputs can be used for the budget allocation and AM distribution improvement in the departments of surgery, as well as for the development and efficacy control of the local antimicrobial stewardship programs.

  8. Hazard And Risk Slope Inventory Using Geographical Information System (GIS): Case Study At Federal Route Simpang Pulai From Section 35 To 45

    Science.gov (United States)

    Kaamin, Masiri; Abd Kadir, Aslila; Nadzira Abu Zarin, Nurul; Farah Atiqah Ahmad, Nor; Nooraiin Mohd Razali, Siti; Mohd Bukari, Saifullizan; Anjang Ahmad, Mustaffa

    2016-11-01

    The demand for better and efficient road network has increased tremendously due to the rapid development experienced by the nation in the past few decades. Thus, the tendency to construct roads on the hilly terrain and forced the cuts and fills activities to be carried out. From Public Work Department (PWD) data, the second East West Highway (EWH) found 1335 numbers of non-failed and failed slopes along the highway that are need to be inspected. This case study was focused along the federal road of Simpang Pulai from section 35 to 45 which is part of the second EWH. Therefore, in order to manage the large number of the slopes, it is impossible to access the location and condition of slopes by conducting site inventory without any references. The Slope Smart Proforma A1 and Slope Management and Risk Tracking System (SMART) assessment was used to collect all the slopes data and analyzed the slope in order to verify the condition in terms of hazard and risk. The process of slope mapping was conducted using the Geographic Information System (GIS) application. As a result, the map of slope hazard and risk produced based on rating that has been designed by PWD in SMART. In conclusion, the map produced with data collected through proforma can be useful for the responsible parties to evaluate and inspect the condition of the slopes in order to take early preventive measures.

  9. [Normal values of temporal parameters of ECG in children according to results of clinico-epidemiological study ECG-screening of children and adolescents in Russian federation].

    Science.gov (United States)

    Miklashevich, I M; Shkol'nikova, M A; Kalinin, L A; Abdullatipova, I V; Osokina, G G; Deev, A D; Blinova, A V; Drozdova, A I; Lebed'kova, S E; Muratov, R A; Verevkina, O N; Timukova, A K; Lunegova, E V; Kozlova, L V; Svintsova, L I; Khomiakova, O I; Ashcheulova, N L

    2009-01-01

    In order to obtain reliable information about time-domain ECG parameters in Russian children and to analyse their links with physiological changes the Project "ECG screening of children and adolescents of the Russian Federation" was carried out in 2003-2008. Time domain ECG parameters were studied in the representative sample of 5387 healthy individuals aged 0 to 18 years. In each age group, lower and upper limits of the norm for heart rate (HR), P wave, PQ and QRS intervals were defined as 2nd and 98th percentiles of their distribution. The equivalent limits of QT interval duration were defined as its 5th and 95th percentiles. Relationship between time domain parameters of pediatric ECG and HR was analyzed as well as relationship of these parameters with sex and age. The most important differences from prior pediatric studies completed 30 years ago were obtained for the heart rate limits. Among children aged 0 to 3, there was a tendency toward lowering of age-specific lower limits and elevation of age-specific upper limits. At ages older than 3 years, there was a tendency toward lowering of both the upper and the lower limits of HR. The newly obtained 2nd percentiles of the heart rate were lower than the known lower limits in nearly all ages. This indicates the necessity for revision of criteria of bradicardia in children. The present study showed that 5th and 95th percentiles of QTc interval (Bazett's formula) varied between 340 ms and 465 ms and were not significantly dependent on children's age and only for ages under 13 also on sex. Results of the study allowed to build age-specific ranges of norm for the time domain ECG parameters presented in a tabular form.

  10. Intramedullary tumours in patients with neurofibromatosis type 2: MRI features associated with a favourable prognosis

    Energy Technology Data Exchange (ETDEWEB)

    Rennie, A.T.M. [Department of Neuroradiology, West Wing, John Radcliffe Hospital, Headington, Oxford (United Kingdom)], E-mail: atmrennie@hotmail.com; Side, L. [Department of Clinical Genetics, Churchill Hospital, Headington, Oxford (United Kingdom); Kerr, R.S.C. [Department of Neurosurgery, West Wing, John Radcliffe Hospital, Headington, Oxford (United Kingdom); Anslow, P.; Pretorius, P. [Department of Neuroradiology, West Wing, John Radcliffe Hospital, Headington, Oxford (United Kingdom)

    2008-02-15

    Aim: To assess the magnetic resonance imaging (MRI) features and natural history of intramedullary tumours in patients with neurofibromatosis type 2 (NF2). Materials and methods: Eleven NF2 patients with intramedullary spinal cord tumours were identified from the database of the multidisciplinary NF2 clinic. All the imaging studies of these patients were individually reviewed by two neuroradiologists to evaluate the size, number, location, imaging characteristics, and interval growth of the intramedullary tumours. Results: Two of the 11 patients had lesions that required surgery. Both these lesions were in the cervical region, and extended over three and five segments respectively. Nine patients with a mean imaging follow-up period of 77 months had lesions that remained stable, apart from the development of small peritumoral cysts in three. The lesions were well circumscribed, often multiple, usually less than 1 cm in diameter, and were most frequently found in the cervical cord. Conclusion: The majority of intramedullary tumours in NF2 patients are very slow growing and share certain MRI features that differ from those of progressive or symptomatic lesions.

  11. Pyridoxine-dependent epilepsy due to antiquitin deficiency: achieving a favourable outcome.

    Science.gov (United States)

    Oliveira, Renata; Pereira, Cristina; Rodrigues, Fidjy; Alfaite, Claudia; Garcia, Paula; Robalo, Conceição; Fineza, Isabel; Gonçalves, Olavo; Struys, Eduard; Salomons, Gajja; Jakobs, Cornelis; Diogo, Luísa

    2013-12-01

    We report 4 pyridoxine-dependent epilepsy patients in which good outcome was determined in three. The 4 patients were male and aged from 7 to 24 years old (from three unrelated Caucasian families). A clinical diagnosis of neonatal pyridoxine-dependent epilepsy was confirmed by biochemical and genetic studies. Clinical evaluation was performed and medical records were reviewed for therapy implementation and management, neurodevelopment outcome, magnetic resonance imaging, and electroencephalography. All were taking pyridoxine treatment and were seizure-free. Elevated urinary alpha-aminoadipic semialdehyde excretion was found in all patients. Antiquitin gene analysis identified a large homozygous deletion in one patient and two heterozygous mutations in the others. Treatment with pyridoxine should be attempted for all cases of infantile and childhood refractory epilepsy, as has been the case over the last 20 years. Currently, urinary alpha-aminoadipic semialdehyde is a reliable biomarker of pyridoxine-dependent epilepsy, even under pyridoxine treatment. Detection of mutations in the antiquitin gene, encoding alpha-aminoadipic semialdehyde dehydrogenase, establishes the diagnosis and allows for adequate genetic counselling.

  12. Foreign direct investment in the health care sector and most-favoured locations in developing countries.

    Science.gov (United States)

    Outreville, J François

    2007-12-01

    Given the growing importance of the health care sector and the significant development of trade in health services, foreign direct investment (FDI) in this sector has gathered momentum with the General Agreement on Trade in Services. Despite extensive case based research and publications in recent years on health care markets and the rise of private sectors, it is surprisingly difficult to find evidence on the relative importance of the largest multinational corporations (MNCs) operating in the health care sector. The objective of the paper is to identify some of the determinants of foreign investment of the largest MNCs operating in this industry. The list of the largest MNCs has been compiled using company websites and data is available for 41 developing economies for which at least two MNCs have an office (branch and/or affiliate). The results of this study have some important implications. They indicate that location-specific advantages of host countries, including good governance, do provide an explication of the internationalization of firms in some developing countries rather than others.

  13. To evaluate stereoacuity in patients with acquired esotropia and to determine factors associated with favourable outcomes

    Directory of Open Access Journals (Sweden)

    Monisha E Nongpiur

    2014-01-01

    Full Text Available Aim: To evaluate stereoacuity in patients with acquired esotropia and determine the factors associated with favorable outcomes. Materials and Methods: A total of 68 subjects aged 6 years and above were included in the study. Thorough clinical evaluation including binocular status examination using the Bagolini-striated glass test, The Netherland Organization (TNO, and Randot stereo test were done. The subjects were divided into two groups 1 and 2, based on the amount of deviation. Statistical analysis of the result was performed. Result: The duration of misalignment in the group with deviation less than or equal to 8 prism diopters (PD was 1.49 ± 0.86 years, whereas in the group with deviation more than or equal to 10 PD was 4.64 ± 2.99 years (P = 0.000. Among the subjects in group 1, 89.5% achieved fusion and 52.6% had stereoacuity on both TNO and Randot, whereas in group 2 40% achieved fusion and 3.3% stereopsis on both TNO and Randot (one case with only coarse stereopsis. A subanalysis within group 1 revealed a statistically significant difference for the duration of misalignment (P = 0.02, but a marginal difference for the amount of deviation (P = 0.3. Conclusion: A horizontal deviation up to 8 PD was compatible with stereopsis. Also, the duration of constant misalignment affects the attainment of stereopsis despite successful realignment.

  14. Hidden epistastic interactions can favour the evolution of sex and recombination.

    Directory of Open Access Journals (Sweden)

    Joel R Peck

    Full Text Available Deleterious mutations can have a strong influence on the outcome of evolution. The nature of this influence depends on how mutations combine together to affect fitness. "Negative epistasis" occurs when a new deleterious mutation causes the greatest loss in fitness in a genome that already contains many deleterious mutations. Negative epistasis is a key ingredient for some of the leading hypotheses regarding the evolution of recombination, the evolution of sex, and a variety of other phenomena. In general, laboratory studies have not supported the idea that negative epistasis is ubiquitous, and this has led to doubts about its importance in biological evolution. Here, we show that these experimental results may be misleading, because negative epistasis can produce evolutionary advantages for sex and recombination while simultaneously being almost impossible to detect using current experimental methods. Under asexual reproduction, such hidden epistasis influences evolutionary outcomes only if the fittest individuals are present in substantial numbers, while also forming a very small proportion of the population as a whole. This implies that our results for asexuals will apply only for very large populations, and also limits the extent of the fitness benefits that hidden epistasis can provide. Despite these caveats, our results show that the fitness consequences of sex and recombination cannot always be inferred from observable epistasis alone.

  15. Fortune favours the brave: Movement responses shape demographic dynamics in strongly competing populations.

    Science.gov (United States)

    Potts, Jonathan R; Petrovskii, Sergei V

    2017-05-07

    Animal movement is a key mechanism for shaping population dynamics. The effect of interactions between competing animals on a population's survival has been studied for many decades. However, interactions also affect an animal's subsequent movement decisions. Despite this, the indirect effect of these decisions on animal survival is much less well-understood. Here, we incorporate movement responses to foreign animals into a model of two competing populations, where inter-specific competition is greater than intra-specific competition. When movement is diffusive, the travelling wave moves from the stronger population to the weaker. However, by incorporating behaviourally induced directed movement towards the stronger population, the weaker one can slow the travelling wave down, even reversing its direction. Hence movement responses can switch the predictions of traditional mechanistic models. Furthermore, when environmental heterogeneity is combined with aggressive movement strategies, it is possible for spatially segregated co-existence to emerge. In this situation, the spatial patterns of the competing populations have the unusual feature that they are slightly out-of-phase with the environmental patterns. Finally, incorporating dynamic movement responses can also enable stable co-existence in a homogeneous environment, giving a new mechanism for spatially segregated co-existence. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Patulin is a cultivar-dependent aggressiveness factor favouring the colonization of apples by Penicillium expansum.

    Science.gov (United States)

    Snini, Selma P; Tannous, Joanna; Heuillard, Pauline; Bailly, Sylviane; Lippi, Yannick; Zehraoui, Enric; Barreau, Christian; Oswald, Isabelle P; Puel, Olivier

    2016-08-01

    The blue mould decay of apples is caused by Penicillium expansum and is associated with contamination by patulin, a worldwide regulated mycotoxin. Recently, a cluster of 15 genes (patA-patO) involved in patulin biosynthesis was identified in P. expansum. blast analysis revealed that patL encodes a Cys6 zinc finger regulatory factor. The deletion of patL caused a drastic decrease in the expression of all pat genes, leading to an absence of patulin production. Pathogenicity studies performed on 13 apple varieties indicated that the PeΔpatL strain could still infect apples, but the intensity of symptoms was weaker compared with the wild-type strain. A lower growth rate was observed in the PeΔpatL strain when this strain was grown on nine of the 13 apple varieties tested. In the complemented PeΔpatL:patL strain, the ability to grow normally in apple and the production of patulin were restored. Our results clearly demonstrate that patulin is not indispensable in the initiation of the disease, but acts as a cultivar-dependent aggressiveness factor for P. expansum. This conclusion was strengthened by the fact that the addition of patulin to apple infected by the PeΔpatL mutant restored the normal fungal colonization in apple.

  17. Diverse seed banks favour adaptation of microalgal populations to future climate conditions.

    Science.gov (United States)

    Kremp, Anke; Oja, Johanna; LeTortorec, Anniina H; Hakanen, Päivi; Tahvanainen, Pia; Tuimala, Jarno; Suikkanen, Sanna

    2016-02-01

    Selection of suitable genotypes from diverse seed banks may help phytoplankton populations to cope with environmental changes. This study examines whether the high genotypic diversity found in the Baltic cyst pool of the toxic dinoflagellate Alexandrium ostenfeldii is coupled to phenotypic variability that could aid short-term adaptation. Growth rates, cellular toxicities and bioluminescence of 34 genetically different clones isolated from cyst beds of four Baltic bloom sites were determined in batch culture experiments along temperature and salinity gradients covering present and future conditions in the Baltic Sea. For all parameters a significant effect of genotype on the response to temperature and salinity changes was identified. General or site-specific effects of the two factors remained minor. Clones thriving at future conditions were different from the best performing at present conditions, suggesting that genotypic shifts may be expected in the future. Increased proportions of highly potent saxitoxin were observed as a plastic response to temperature increase, indicating a potential for higher toxicity of future blooms. The observed standing variation in Baltic seed banks of A. ostenfeldii suggests that the population is likely to persist under environmental change.

  18. Aid and the growth of income in aid-favoured developing countries: policy issues.

    Science.gov (United States)

    Brewster, H; Yeboah, D

    1994-04-01

    This paper opens by expressing disappointment in the disparities between published estimations of the effectiveness of foreign aid to developing countries and effectiveness data which arise from the application of complex econometric methods. The new dilemmas for aid policy include the fact that aid increasingly devoted to human development at the expense of productive activity is unlikely to create the material development which will allow maintenance of human development targets. The second part of the paper presents comparative statistics on gross national product, official development assistance, and savings growth which paint a disturbing picture because the growth of domestic savings has been negative in the period 1967-87 in nine of the 11 less developed countries with data available. Section 3 covers the shortcomings of econometric experiments which neither confirm nor deny the findings of other studies on the effectiveness of aid. The fourth section describes constraints to the growth of income imposed by the foreign exchange, the rate of return on investment, and the growth of labor productivity and presents statistical evidence supporting aid policy which would 1) take advantage of opportunities to rehabilitate output growth in traditional industries without the addition of a great deal of capital, 2) direct attention to increasing the absolute gross national product (GNP) to raise the growth of per capital income, and 3) strategically reorient the structure of aid to increase the absolute GNP faster to accelerate reversal of the negative savings pattern and speed the reduction of fertility. Section 5 considers suggested shifts in aid policy orientation dealing with 1) population growth, income level, and food security; 2) reconstruction and structural adjustment; 3) rationalizing aid for social, institutional, and human development and technical assistance. The concluding section notes that the suggested strategic reorientation of the structure of aid

  19. From favours to entitlements: community voice and action and health service quality in Zambia

    Science.gov (United States)

    Topp, Stephanie M.; Ngulube, Moses

    2017-01-01

    Abstract Social accountability is increasingly invoked as a way of improving health services. This article presents a theory-driven qualitative study of the context, mechanisms and outcomes of a social accountability program, Citizen Voice and Action (CVA), implemented by World Vision (WV) in Zambia. Primary data were collected between November 2013 and January 2014. It included in-depth interviews and focus group discussions with program stakeholders. Secondary data were used iteratively—to inform the process for primary data collection, to guide primary data analysis and to contextualize findings from the primary data. CVA positively impacted the state, society, state–society relations and development coordination at the local level. Specifically, sustained improvements in some aspects of health system responsiveness, empowered citizens, the improved provision of public goods (health services) and increased consensus on development issues appeared to flow from CVA. The central challenge described by interviewees and FGD participants was the inability of CVA to address problems that required central level input. The mechanisms that generated these outcomes included productive state–society communication, enhanced trust, and state–society co-production of priorities and the provision of services. These mechanisms were activated in the context of existing structures for state–society interaction, willing political leaders, buy-in by traditional leaders, and WV’s strong reputation and access to resources. Prospective observational research in multiple contexts would shed more light on the context, mechanisms and outcomes of CVA programs. In addition to findings that are intuitive and well supported in the literature we identified new areas that are promising areas for future research. These include (1) the context of organizational reputation by the organization(s) spearheading social accountability efforts; (2) the potential relationship between social

  20. Adiponectin expression in patients with inflammatory cardiomyopathy indicates favourable outcome and inflammation control.

    Science.gov (United States)

    Bobbert, Peter; Scheibenbogen, Carmen; Jenke, Alexander; Kania, Gabriele; Wilk, Sabrina; Krohn, Stefanie; Stehr, Jenny; Kuehl, Uwe; Rauch, Ursula; Eriksson, Urs; Schultheiss, Heinz Peter; Poller, Wolfgang; Skurk, Carsten

    2011-05-01

    Circulating adiponectin (APN) is an immunomodulatory, pro-angiogenic, and anti-apoptotic adipocytokine protecting against acute viral heart disease and preventing pathological remodelling after cardiac injury. The purpose of this study was to describe the regulation and effects of APN in patients with inflammatory cardiomyopathy (DCMi). Adiponectin expression and outcome were assessed in 173 patients with DCMi, 30 patients with non-inflammatory DCM, and 30 controls. Mechanistic background of these findings was addressed in murine experimental autoimmune myocarditis (EAM), a model of human DCMi, and further elucidated in vitro. Adiponectin plasma concentrations were significantly higher in DCMi compared with DCM or controls, i.e. 6.8 ± 3.9 µg/mL vs. 5.4 ± 3.6 vs. 4.76 ± 2.5 µg/mL (P< 0.05, respectively) and correlated significantly with cardiac mononuclear infiltrates (CD3+: r(2)= 0.025, P= 0.038; CD45R0+: r(2)= 0.058, P= 0.018). At follow-up, DCMi patients with high APN levels showed significantly increased left ventricular ejection fraction improvement, decreased left ventricular end-diastolic diameter, and reduced cardiac inflammatory infiltrates compared with patients with low APN levels. A multivariate linear regression analysis implicated APN as an independent prognostic factor for inhibition of cardiac inflammation. In accordance with these findings in human DCMi, EAM mice exhibited elevated plasma APN. Adiponectin gene transfer led to significant downregulation of key inflammatory mediators promoting disease. Mechanistically, APN acted as a negative regulator of T cells by reducing antigen specific expansion (P< 0.01) and suppressed TNFα-mediated NFκB activation (P< 0.01) as well as release of reactive oxygen species in cardiomyocytes. Our results implicate that APN acts as endogenously upregulated anti-inflammatory cytokine confining cardiac inflammation and progression in DCMi.

  1. Exploring the effects of roadway characteristics on the frequency and severity of head-on crashes: case studies from Malaysian federal roads.

    Science.gov (United States)

    Hosseinpour, Mehdi; Yahaya, Ahmad Shukri; Sadullah, Ahmad Farhan

    2014-01-01

    Head-on crashes are among the most severe collision types and of great concern to road safety authorities. Therefore, it justifies more efforts to reduce both the frequency and severity of this collision type. To this end, it is necessary to first identify factors associating with the crash occurrence. This can be done by developing crash prediction models that relate crash outcomes to a set of contributing factors. This study intends to identify the factors affecting both the frequency and severity of head-on crashes that occurred on 448 segments of five federal roads in Malaysia. Data on road characteristics and crash history were collected on the study segments during a 4-year period between 2007 and 2010. The frequency of head-on crashes were fitted by developing and comparing seven count-data models including Poisson, standard negative binomial (NB), random-effect negative binomial, hurdle Poisson, hurdle negative binomial, zero-inflated Poisson, and zero-inflated negative binomial models. To model crash severity, a random-effect generalized ordered probit model (REGOPM) was used given a head-on crash had occurred. With respect to the crash frequency, the random-effect negative binomial (RENB) model was found to outperform the other models according to goodness of fit measures. Based on the results of the model, the variables horizontal curvature, terrain type, heavy-vehicle traffic, and access points were found to be positively related to the frequency of head-on crashes, while posted speed limit and shoulder width decreased the crash frequency. With regard to the crash severity, the results of REGOPM showed that horizontal curvature, paved shoulder width, terrain type, and side friction were associated with more severe crashes, whereas land use, access points, and presence of median reduced the probability of severe crashes. Based on the results of this study, some potential countermeasures were proposed to minimize the risk of head-on crashes.

  2. The acceptability of arguments in favour of and against the Iraq War

    Directory of Open Access Journals (Sweden)

    Juan LaLlave

    2005-10-01

    Full Text Available This paper reports on research based on an experimental questionnaire designed using the logic and the basic structure of the Moral Judgment Test (MJT by Lind (1982. The study aims at understanding how respondents' acceptance of political arguments may have contributed to the lack of international support for the Iraq war and/or to the failure to prevent a preemptive attack. It examines factors, which respondents may have relied on in their acceptance of the arguments. The instrument consisted of three components: (1 A brief vignette on the declared beginning (March 19, 2003 and ending (May 1, 2003 of major operations in Iraq. (2 Respondents' own agreement with the need for the war. (3 Twelve arguments from political speeches: Six arguments by Bush and Blair "in favor of" (pro, and six arguments by Chirac and Schroeder "against" (con the need for the Iraq war. We scored each argument using Kohlberg's (1984 stage theory and Commons' Hierarchical Complexity Scoring System (HCSS (Commons et al., 2004, which identifies hierarchical features in the structure. Using Kempf's (2003 Cognitive Escalation and De-Escalation Model (CEDM we scored each argument sentence for details. Our sample consists of (N = 397 respondents of which were 56.4% women, 24.2% men, and 19.4% did not specify. The largest groups consisted of 71% Germans, 37.2% Catholics, 74.3% between the ages of 18-20 with high school education. Another group consisted of 8.6% Americans with a broader spectrum in age and higher educational level. Using 7 point Likert scales, respondents rated whether they would have rejected or accepted the main point of each argument, whether the main point of the argument seemed illusory or realistic, and whether the emotion evoked by the argument was destructive or constructive. The analysis of the data aimed at determining which within subject and between subject design factors were relevant in predicting respondents' acceptance of arguments and the

  3. Promoting greater Federal energy productivity [Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, Mark; Dudich, Luther

    2003-03-05

    This document is a close-out report describing the work done under this DOE grant to improve Federal Energy Productivity. Over the four years covered in this document, the Alliance To Save Energy conducted liaison with the private sector through our Federal Energy Productivity Task Force. In this time, the Alliance held several successful workshops on the uses of metering in Federal facilities and other meetings. We also conducted significant research on energy efficiency, financing, facilitated studies of potential energy savings in energy intensive agencies, and undertook other tasks outlined in this report.

  4. Defensive Federal Litigation

    Science.gov (United States)

    1998-08-20

    Unidos , Inc. v. United States Dep’t of Labor, 803 F.2d 1063, 1068 (9th Cir. 1986); Ameron, Inc. v. United States Army Corps of Eng’rs, 787 F.2d 875 (3d...Federal Circuit 59Diekan v. Stone, 995 F.2d 1061 (1st Cir. 1993); Penagaricano v. Llenza, 747 F.2d 55 (1st Cir. 1984); Guerra v. Scruggs, 942 F.2d 270

  5. Federal Interagency Geothermal Activities

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Arlene [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States); Prencipe, Loretta [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States); Todaro, Richard M. [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States); Cuyler, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Eide, Elizabeth [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2011-06-01

    This collaborative document describes the roles and responsibilities of key Federal agencies in the development of geothermal technologies including the U.S. Department of Energy (DOE); the U.S. Department of Agriculture (USDA), including the U.S. Forest Service; the U.S. Department of Interior (DOI), including the United States Geological Survey (USGS) and Bureau of Land Management (BLM); the Environmental Protection Agency (EPA); and the Department of Defense (DOD).

  6. 76 FR 30139 - Federal Need Analysis Methodology for the 2012-2013 Award Year

    Science.gov (United States)

    2011-05-24

    ..., Federal Perkins Loan, Federal Work-Study, Federal Supplemental Educational Opportunity Grant, William D... Opportunity Grant, William D. Ford Federal Direct Loan, and the Teach Grant Programs (Title IV, HEA Programs... Programs; 84.007 Federal Supplemental Educational Opportunity Grant Program; 84.268 William D. Ford...

  7. Tax incentives in fiscal federalism

    DEFF Research Database (Denmark)

    Kelders, Christian; Köthenbürger, Marko

    2010-01-01

    Models of fiscal federalism rarely account for the efficiency implications of intergovernmental fiscal ties for federal tax policy. This paper shows that fiscal institutions such that federal tax deductibility, vertical revenue-sharing, and fiscal equalization (being common features of existing...... federations) encourage local taxation, but may discourage federal taxation. Furthermore, the structure of public spending is skewed towards local spending. We also show that, when considering Leviathan governments, fiscal institutions reduce confiscatory taxation by the federal government. The result...... is contrary to the Cartelization Hypothesis ( Brennan and Buchanan 1980 ). Finally, we characterize the efficient design of intergovernmental fiscal ties....

  8. Perception about the Medical Internship at Federal University of Rio de Janeiro by the Service’s Preceptors in Primary Health Care: a Case Study

    Directory of Open Access Journals (Sweden)

    Salesia Felipe de Oliveira

    Full Text Available ABSTRACT Introduction A preceptor is understood as a health care professional with an important role in introducing students and recently graduated doctors into professional practice. However, studies into medical teaching in the Family Health Strategy (FHS have shown inadequacies in the quality, training and time spent by the tutors with students. In the municipality of Rio de Janeiro (RJ, the expansion of the FHS was belated, resulting in a vacuum of medical students being inserted into the network. Objective To understand the perception of Family Health Strategy physician preceptors regarding their performance with medical student interns from the Federal University of Rio de Janeiro (UFRJ. Methods This is a case study which employed a qualitative method and took place in the city of Rio de Janeiro (RJ. Semi-structured interviews were conducted between September 2011 and March 2012, with 15 preceptors from six Family Clinics receiving UFRJ medical interns. Interviews were recorded, transcribed, read and subjected to thematic content analysis, resulting in the establishment of five categories: encouragement and motivation; appreciation; training; real world versus academic world; teaching-service integration. Results The preceptors report that they feel recognized and encouraged by the students, but do not feel appreciated by the service coordinators, who fail to allocate adequate space and time to their preceptorship activities. A good relationship is established with both tutors and students. The preceptors would like to be trained in preceptorship and to strengthen their ties to UFRJ. They view their time with the students as both precious and challenging, because it stimulates them to rethink their care practices. They recognize in the internship the opportunity for students to gain practical experience of what has been learned in theory. Conclusion The preceptors’ work is supported by the good relationship established between preceptors

  9. Evaluation of the Impact of EISA Federal Project Investments

    Energy Technology Data Exchange (ETDEWEB)

    Judd, Kathleen S.; Wendel, Emily M.; Morris, Scott L.; Williamson, Jennifer L.; Halverson, Mark A.; Livingston, Olga V.; Loper, Susan A.

    2012-12-31

    The DOE's Federal Energy Management Program has been charged by Office of Management and Budget to conduct an evaluation on actual and verifiable energy savings and carbon emissions reductions from federal energy management investments made across the Federal government as a result of the Energy Independence and Security Act of 2007. This study presents the findings from that evaluation.

  10. Federating Metadata Catalogs

    Science.gov (United States)

    Baru, C.; Lin, K.

    2009-04-01

    The Geosciences Network project (www.geongrid.org) has been developing cyberinfrastructure for data sharing in the Earth Science community based on a service-oriented architecture. The project defines a standard "software stack", which includes a standardized set of software modules and corresponding service interfaces. The system employs Grid certificates for distributed user authentication. The GEON Portal provides online access to these services via a set of portlets. This service-oriented approach has enabled the GEON network to easily expand to new sites and deploy the same infrastructure in new projects. To facilitate interoperation with other distributed geoinformatics environments, service standards are being defined and implemented for catalog services and federated search across distributed catalogs. The need arises because there may be multiple metadata catalogs in a distributed system, for example, for each institution, agency, geographic region, and/or country. Ideally, a geoinformatics user should be able to search across all such catalogs by making a single search request. In this paper, we describe our implementation for such a search capability across federated metadata catalogs in the GEON service-oriented architecture. The GEON catalog can be searched using spatial, temporal, and other metadata-based search criteria. The search can be invoked as a Web service and, thus, can be imbedded in any software application. The need for federated catalogs in GEON arises because, (i) GEON collaborators at the University of Hyderabad, India have deployed their own catalog, as part of the iGEON-India effort, to register information about local resources for broader access across the network, (ii) GEON collaborators in the GEO Grid (Global Earth Observations Grid) project at AIST, Japan have implemented a catalog for their ASTER data products, and (iii) we have recently deployed a search service to access all data products from the EarthScope project in the US

  11. Thermally favourable gauge mediation

    Energy Technology Data Exchange (ETDEWEB)

    Dalianis, Ioannis, E-mail: Ioannis.Dalianis@fuw.edu.p [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw, ul. Hoza 69, Warsaw (Poland); Lalak, Zygmunt, E-mail: Zygmunt.Lalak@fuw.edu.p [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw, ul. Hoza 69, Warsaw (Poland)

    2011-03-14

    We discuss the thermal evolution of the spurion and messenger fields of ordinary gauge mediation models taking into account the Standard Model degrees of freedom. It is shown that for thermalized messengers the metastable susy breaking vacuum becomes thermally selected provided that the susy breaking sector is sufficiently weakly coupled to messengers or to any other observable field.

  12. Mobility into favourable jobs

    OpenAIRE

    Maurice Gesthuizen; Jaco Dagevos

    2005-01-01

    Original title: Arbeidsmobiliteit in goede banen. Hundreds of thousands of employees change jobs each year. Why do they do this, and what benefits do they derive from it? Many employees are not in the right jobs. Job dissatisfaction is found to be a key reason for labour mobility. These employees look for a job that offers a better match for their capacities and preferences. Does changing their job have a positive effect? This report shows that labour mobility does indeed generally lead to a ...

  13. Mobility into favourable jobs

    NARCIS (Netherlands)

    Maurice Gesthuizen; Jaco Dagevos

    2005-01-01

    Original title: Arbeidsmobiliteit in goede banen. Hundreds of thousands of employees change jobs each year. Why do they do this, and what benefits do they derive from it? Many employees are not in the right jobs. Job dissatisfaction is found to be a key reason for labour mobility. These employees

  14. Hindered aryl bromides for regioselective palladium-catalysed direct arylation at less favourable C5-carbon of 3-substituted thiophenes

    Directory of Open Access Journals (Sweden)

    Rongwei Jin

    2014-05-01

    Full Text Available The use of the congested aryl bromide 2-bromo-1,3-dichlorobenzene as coupling partner allows to modify the regioselectivity of the arylation of 3-substituted thiophene derivatives in favour of carbon C5. The coupling of this aryl bromide with a variety of 3-substituted thiophenes gave in all cases the desired 5-arylation products in moderate to good yields using only 0.5 mol % of a phosphine-free and air-stable palladium catalyst. Then, from these 5-arylthiophenes, a second palladium-catalysed C–H bond functionalization at C2 of the thiophene ring allows the synthesis of 2,5-diarylthiophenes with two different aryl units.

  15. RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code.

    Science.gov (United States)

    Di Giulio, Massimo; Moracci, Marco; Cobucci-Ponzano, Beatrice

    2014-10-21

    Here we suggest that the origin of the genetic code, that is to say, the birth of first mRNAs has been triggered by means of a widespread modification of all RNAs (proto-mRNAs and proto-tRNAs), as today observed in the RNA editing and in post-transcriptional modifications of RNAs, which are considered as fossils of this evolutionary stage of the genetic code origin. We consider also that other mechanisms, such as the trans-translation and ribosome frameshifting, could have favoured the transition from an ennuplet code to a triplet code. Therefore, according to our hypothesis all these mechanisms would be reflexive of this period of the evolutionary history of the genetic code. Copyright © 2014. Published by Elsevier Ltd.

  16. Dravet syndrome with favourable cognitive and behavioral development due to a novel SCN1A frameshift mutation.

    Science.gov (United States)

    Jiang, Peifang; Shen, Jue; Yu, Yonglin; Jiang, Lihua; Xu, Jialu; Xu, Lu; Yu, Huimin; Gao, Feng

    2016-07-01

    Children with Dravet syndrome (DS) often have severe cognitive, behaviour and motor impairments. Patients with truncating mutations would logically have the more severe phenotype. Here we present a case of DS with an unusually favourable cognitive and behavioral development with a novel SCN1A frameshift mutation (c.4233-4234insAT). Under regular following up for ten years, the patient had normal expressive language and mild motor clumsiness. It is suggested that besides the type of SCN1A mutation, other mechanisms may be existed to influence the SCN1A phenotype, such as modifier genes, developmental variability, accumulation of somatic mutation in lifetime and environmental insults can all contribute to the cognitive and behavioral outcome.

  17. International and National Organizations, Proceedings: International Federation for Documentation Study Committee "Information for Industry" - FID/II. Meeting Held in the Framework of the ISLIC International Conference on Information Science, Tel Aviv, Sept. 3, 1971.

    Science.gov (United States)

    Israel Society of Special Libraries and Information Centres, Tel Aviv.

    The material published here was presented at an open meeting of the International Federation for Documentation study committee, Information for Industry (FID/II) during the ISLCI International Conference on Information Science on September 3, 1971. (The full proceedings in two volumes are available as ED 065139 and ED 065140.) Contained herein are…

  18. Lehrer in der Bundesrepublik Deutschland. Eine Kritische Analyse Statistischer Daten uber das Lehrpersonal an Allgemeinbildenden Schulen. (Education in the Federal Republic of Germany. A Statistical Study of Teachers in Schools of General Education.)

    Science.gov (United States)

    Kohler, Helmut

    The purpose of this study was to analyze the available statistics concerning teachers in schools of general education in the Federal Republic of Germany. An analysis of the demographic structure of the pool of full-time teachers showed that in 1971 30 percent of the teachers were under age 30, and 50 percent were under age 35. It was expected that…

  19. Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose for the ambulatory treatment of severe iron deficiency.

    Directory of Open Access Journals (Sweden)

    Xavier Calvet

    Full Text Available OBJECTIVE: Intravenous iron is widely used to treat iron deficiency in day-care units. Ferric carboxymaltose (FCM allows administration of larger iron doses than iron sucrose (IS in each infusion (1000 mg vs. 200 mg. As FCM reduces the number of infusions required but is more expensive, we performed a cost-minimization analysis to compare the cost impact of the two drugs. MATERIALS AND METHODS: The number of infusions and the iron dose of 111 consecutive patients who received intravenous iron at a gastrointestinal diseases day-care unit from 8/2007 to 7/2008 were retrospectively obtained. Costs of intravenous iron drugs were obtained from the Spanish regulatory agencies. The accounting department of the Hospital determined hospital direct and indirect costs for outpatient iron infusion. Non-hospital direct costs were calculated on the basis of patient interviews. In the pharmacoeconomic model, base case mean costs per patient were calculated for administering 1000 mg of iron per infusion using FCM or 200 mg using IS. Sensitivity analysis and Monte Carlo simulation were performed. RESULTS: Under baseline assumptions, the estimated cost of iron infusion per patient and year was €304 for IS and €274 for FCM, a difference of €30 in favour of FCM. Adding non-hospital direct costs to the model increased the difference to €67 (€354 for IS vs. €287 for FCM. A Monte Carlo simulation taking into account non-hospital direct costs favoured the use of FCM in 97% of simulations. CONCLUSION: In this pharmacoeconomic analysis, FCM infusion reduced the costs of iron infusion at a gastrointestinal day-care unit.

  20. Federal Securities Regulations and Stock Market Returns

    OpenAIRE

    Tung Liu; Gary Santoni; Courtenay Cliff Stone

    2008-01-01

    This paper examines the impact of federal securities statutes (seven major legislative acts and 535 amendments) on the mean and variance of total real U.S. stock market returns. In contrast to previous work, this study controls for the persistence of the variability of stock returns, employs a longer time period, utilizes a broader array of stocks and examines the impact of seven federal securities regulations and their selected amendments from 1933 through 2001. Despite the popular appeal of...

  1. Integration of Oral Health Into the Well-Child Visit at Federally Qualified Health Centers: Study of 6 Clinics, August 2014–March 2015

    Science.gov (United States)

    Gebel, Christina; Vargas, Clemencia; Geltman, Paul; Walter, Ashley; Garcia, Raul I.; Tinanoff, Norman

    2016-01-01

    Introduction Early childhood caries, the most common chronic childhood disease, affects primary dentition and can impair eating, sleeping, and school performance. The disease is most prevalent among vulnerable populations with limited access to pediatric dental services. These same children generally receive well-child care at federally qualified health centers. The objective of this study was to identify facilitators and barriers to the integration of oral health into pediatric primary care at health centers to improve problem recognition, delivery of preventive measures, and referral to a dentist. Methods We collected and analyzed background data and data from structured observations and 39 interviews with administrators and staff at 6 clinics in 2 states, Maryland and Massachusetts. Results Participants valued oral health across professional roles but cited limited time, lack of training and expertise, low caregiver literacy, and lack of shared medical and dental electronic records as barriers to cooperation. Facilitators included an upper-level administration with the vision to see the value of integration, designated team leaders, and champions. An administration’s vision, not structural determinants, patient characteristics, or geographic location, predicted the level of integration. Interviewees generated multilevel recommendations to promote delivery of oral health preventive measures and services during a well-child visit. Conclusion Poor oral health contributes to health care disparities. Barriers to integrating dental care into pediatric medical practice at health centers must be overcome to improve oral health for children living in poverty, with a disability, at a rural address, or any combination of these. Implementation will require adapting delivery systems to support multidisciplinary collaboration. Strategies suggested here may point the way to enhancing children’s oral health. PMID:27126556

  2. Electronic Code of Federal Regulations

    Data.gov (United States)

    National Archives and Records Administration — The Electronic Code of Federal Regulations (e-CFR) is the codification of the general and permanent rules published in the Federal Register by the executive...

  3. Associate in Occupational Studies, Culinary Arts. Self-Study Report Presented to the Accrediting Commission of the American Culinary Federation Educational Institute.

    Science.gov (United States)

    Schenectady County Community Coll., Schenectady, NY.

    This report is the self-study of the Associate in Occupational Studies (AOS) in Culinary Arts program offered by the Hotel, Culinary Arts, and Tourism Department at Schenectady County Community College (New York). The self-study was conducted to support the department's application for initial accreditation of the Culinary Arts program with the…

  4. The Funding of Social Knowledge Production and Application: A Survey of Federal Agencies. Study Project on Social Research and Development, Volume 2.

    Science.gov (United States)

    Abramson, Mark A.

    This survey is volume two of a six-volume report on the organization and management of social research and development throughout the U.S. government. The main body of the work contains a summary of spending for social research and development for each department of the federal government and the independent agencies. Agencies included are:…

  5. Ignorance Only: HIV/AIDS, Human Rights, and Federally Funded Abstinence-Only Programs in the United States. Texas: A Case Study.

    Science.gov (United States)

    Schleifer, Rebecca

    2002-01-01

    This report contends that programs teaching teenagers to "just say no" to sex before marriage are threatening adolescent health by censoring basic information about how to prevent HIV/AIDS. The report focuses on federally funded "abstinence-only-until-marriage" programs in Texas, where advertising campaigns convey the message…

  6. Modeling data federations in ORM

    NARCIS (Netherlands)

    Balsters, Herman; Halpin, Terry; Meersman, R; Tari, Z; Herrero, P

    2007-01-01

    Two major problems in constructing data federations (for example, data warehouses and database federations) concern achieving and maintaining consistency and a uniform representation of the data on the global level of the federation. The first step in creating uniform representations of data is know

  7. NADA/DOD Aerospace Knowledge Diffusion Research Project. Report number 19: The US government technical report and the transfer of federally funded aerospace R/D: An analysis of five studies

    Science.gov (United States)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the 'NASA/DoD Aerospace Knowledge Diffusion Research Project'. In this report, we summarize the literature on technical reprts and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from five studies of our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report and close with a brief overview of on-going research into the use of the U.S. government technical report as a rhetorical device for transferring federally funded aerospace R&D.

  8. Integrating Vocational and General Education: A Rudolf Steiner School. Case Study of the Hibernia School, Herne, Federal Republic of Germany. UIE Case Studies 1.

    Science.gov (United States)

    Rist, Georg; Schneider, Peter

    This study describes and analyzes the Hibernia School where the aim of curriculum articulation in its essential vertical and horizontal dimensions has been successfully converted into actual practice. (Curriculum articulation means the equal representation and integration of three major components--artistic, practical, and academic learning.)…

  9. Exercise training favourably affects autonomic and blood pressure responses during mental and physical stressors in African-American men.

    Science.gov (United States)

    Bond, V; Bartels, M N; Sloan, R P; Millis, R M; Zion, A S; Andrews, N; De Meersman, R E

    2009-04-01

    Aerobic exercise is a powerful mechanism by which cardiovascular and autonomic parameters may be improved. We sought to quantify the extent of benefit that could be achieved by a short-term monitored exercise regimen on several autonomic parameters during recognized mental and physical stressors in young normotensive African-American men matched for a family history of hypertension, a group at high risk for the development of hypertension. Autonomic modulations were derived using spectral decomposition of the electrocardiogram and beat-to-beat blood pressures (BPs). Arterial compliance was obtained using contour analysis of the radial artery pulse wave. The analysis of variance revealed that compared with a matched sedentary control group, aerobic capacity of the trained group significantly increased by 16%. Autonomic modulations, arterial compliance and BP responses significantly improved during some of the stressors, whereas no such improvements were seen in the control group. Attenuated responses, mediated through a favourable shift in sympathovagal balance and enhanced arterial compliance, provide mechanistic evidence of how certain variables may be improved due to aerobic conditioning in a population at high risk for the development of hypertension.

  10. Post-fire environments are favourable for plant functioning of seeder and resprouter Mediterranean shrubs, even under drought.

    Science.gov (United States)

    Parra, Antonio; Moreno, José M

    2017-05-01

    Understanding how drought affects seeder and resprouter plants during post-fire regeneration is important for the anticipation of Mediterranean vegetation vulnerability in a context of increasing drought and fire caused by climate change. A Mediterranean shrubland was subjected to various drought treatments (including 45% rainfall reduction, 7 months drought yr(-1) ), before and after experimental burning, by means of a rainout-shelter system with an irrigation facility. Predawn shoot water potential (Ψpd ), relative growth rate (RGR), specific leaf area (SLA) and bulk leaf carbon isotopic composition (δ(13) C) were monitored in the main woody species during the first 3 yr after fire. Cistus ladanifer seedlings showed higher Ψpd , RGR and SLA, and lower δ(13) C, than unburned plants during the first two post-fire years. Seedlings under drought maintained relatively high Ψpd , but suffered a decrease in Ψpd and RGR, and an increase in δ(13) C, relative to control treatments. Erica arborea, E. scoparia and Phillyrea angustifolia resprouts had higher Ψpd and RGR than unburned plants during the first post-fire year. Resprouters were largely unaffected by drought. Overall, despite marked differences between the two functional groups, post-fire environments were favourable for plant functioning of both seeder and resprouter shrubs, even under the most severe drought conditions implemented. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  11. Power consumption in detail of private households in the Federal Republic of Germany 1997 - 2000. Study; Detaillierung des Stromverbrauchs privater Haushalte in der Bundesrepublik Deutschland 1997 - 2010. Studie

    Energy Technology Data Exchange (ETDEWEB)

    Boede, U.; Bradke, H.; Cremer, C.

    2000-12-01

    The study includes all electric appliances except for those used to heat rooms. 53 of these power-consuming appliances were also examined in detail as to their idle-power consumption (consumption during stand-by and apparent non-activity). The investigations covered specific performance, the typical sort of use and the development of the stocks. 1997 was used as the basic year. The development is estimated for the years 2000, 2005 and 2010. To identify the stand-by losses, the operational states were defined accurately. This makes it possible to determine which loss is caused by which operational mode. [German] Die Studie beruecksichtigt alle Elektrogeraete ausser solche fuer Raumwaerme. 53 dieser stromverbrauchenden Geraete wurden darueber hinaus bezueglich ihres Leerlaufverbrauchs (Verbrauch im Bereitschaftsbetrieb und im Schein-Aus-Zustand) detailliert betrachtet. Untersucht wurden die spezifische Leistungsaufnahme, die typische Anwendung und die Bestandsentwicklung. Als Basisjahr wurde 1997 herangezogen. Die Entwicklung wird abgeschaetzt fuer die Jahre 2000, 2005 und 2010. Zur Identifizierung der Leerlaufverluste wurde eine genaue Definition der Betriebszustaende vorgenommen. Dadurch ist es moeglich zuzuordnen, welcher Verlust auf welchen Betriebsmodus entfaellt. (orig.)

  12. Hemoglobinopatias no Distrito Federal, Brasil

    Directory of Open Access Journals (Sweden)

    J. Tavares-Neto

    1986-03-01

    Full Text Available Em uma amostra de 3137 pessoas, residentes no Distrito Federal, foram detectadas as seguintes hemoglobinas: em 3009(95,92% HbAA; em 91 (2,90% HbAS; em 20(0,64% HbAC; em 8 (0,26% talassemia beta minor; em 5(0,16% HbAJ alfa; em 3 (0,09% HbAM e em 1 (0,03% talassemia major associada com HbAS. A HbAS têm as seguintes freqüências, quanto ao grupo racial: branco - 1,84%; mulato claro 2,55%; mulato médio-3,68%; mulato escuro - 6,80%; negro -10,43% e mestiço de índio -3,85%.The hemoglobins of 3137 persons from the Federal District, Brazil was studied. The identified types of hemoglobins were: HbAA (3009 - 95,92%; HbAS (91 - 2,90%; HbAC (20 - 0,64% beta thalassemia minor (8 - 0,26%; HbAJ alpha (5 - 0,16%; HbAM (3 - 0,09% and beta thalassemia major/HbS (1 - 0,03%. The frequencies of sickle cell trait (HbAS of each racial class were: white (1,84%; light mulatto (2,55%; medium mulatto (3,68%; dark mulatto(6,80%, negro (10,43%and indian mestizo (3,85%.

  13. Mortality of the elderly is still exceedingly high at diagnosis of AIDS despite favourable outcomes after highly active antiretroviral therapy in Recife, Brazil.

    Science.gov (United States)

    Lacerda, H R; Kitner, D

    2008-07-01

    This study aimed to compare the outcome of an elderly group of AIDS patients with that of a younger group and their features at the time of the diagnosis of AIDS. We evaluated 58 patients aged >60 years and 114 aged 20-39 years, followed for 35.3 months. There was an obvious delay in diagnosing the elderly as they had more AIDS-defining diseases at diagnosis and their most frequent opportunistic infection was pulmonary tuberculosis. Mortality at the time of the diagnosis of AIDS was four times higher in the elderly (24.1% versus 6.1%, P therapy, there was a similar frequency of favourable outcomes; 76.9% in the elderly against 83.1% in the young (P = 0.455). Mean CD4 lymphocyte was 438 cells/mm(3) at the end of follow up in the young when compared with 442 cells/mm(3) in the elderly (P = 0.945). The types of antiretroviral schema and the number of antivirals per patient were similar in both groups.

  14. 75 FR 38999 - Federal Perkins Loan Program: Federal Family Education Loan Program and William D. Ford Federal...

    Science.gov (United States)

    2010-07-07

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF EDUCATION Federal Perkins Loan Program: Federal Family Education Loan Program and William D. Ford Federal Direct... qualifications may have a portion of their Federal Perkins Loan (Perkins Loan), Federal Family Education...

  15. Provision of educational service with the use of distance technologies for disabled persons (case study: the state of Alaska and Nothern regions of the Russian Federation

    Directory of Open Access Journals (Sweden)

    V. A. Lipatov

    2016-01-01

    Full Text Available The distance education contributes to the solution of educational problems of disabled persons. The study of foreign experience is extremely important. North American universities saved up a wide experience in this sphere. Unlike self-made software products created by many Russian universities, Blackboard is the leading educational software package that professionally helps to solve educational problems of disabled persons. The international University of the Arctic has a growing interest in the use of information communication technologies and open educational resources and networks. In 2008 the subject network of University of the Arctic on distance education and e-learning began to function. The Internet and distance learning creates a new opportunity for disabled persons. Main goal: Whether distance education on Alaska and in Northern and Siberian regions of the Russian Federation promotes the solution of educational problems of the North for disabled persons. Main research problems: to reveal modern educational Arctic problems for disabled persons; to analyse specifics of remote education; to analyse a question of distance training of the circumpolar North; to carry out the comparative analysis of distance training on Alaska and in Russian northern and the Siberian regions; to analyse a contribution of distance training to wider problems of the Arctic policy and management. Relevance of work: The Arctic Human Development Report I specifi es that there are very few circumpolar researches in the fi eld of education, including for disabled persons. This article can begin initial discussion of a subject which can be in addition studied in future works. An emerging trend for Arctic education is its increasing accessibility. Accessibility is about students being able to take classes and fulfi ll their potential, that is, it concerns their possibilities for attending school, both physically and culturally. Even though this

  16. 75 FR 18014 - Federal Highway Administration

    Science.gov (United States)

    2010-04-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Highway Administration AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of...: Federal Highway Administration, Kentucky Division: Mr. Greg Rawlings, Transportation Specialist, 330...

  17. 78 FR 9771 - Federal Highway Administration

    Science.gov (United States)

    2013-02-11

    ... Federal Highway Administration Notice of Final Federal Agency Action on Proposed Transportation Project in Illinois and Indiana AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of limitation on..., Federal Highway Administration, 3250 Executive Park Drive, Springfield, Illinois 62703, Phone: (217)...

  18. Federal Environmental Requirements for Construction

    Data.gov (United States)

    Department of Veterans Affairs — This guide provides information on federal environmental requirements for construction projects. It is written primarily for owners of construction projects and for...

  19. Federal Buildings Supplemental Survey 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    The Energy Information Administration (EIA) of the US Department of Energy (DOE) is mandated by Congress to be the agency that collects, analyzes, and disseminates impartial, comprehensive data about energy including the volume consumed, its customers, and the purposes for which it is used. The Federal Buildings Supplemental Survey (FBSS) was conducted by EIA in conjunction with DOE`s Office of Federal Energy Management Programs (OFEMP) to gain a better understanding of how Federal buildings use energy. This report presents the data from 881 completed telephone interviews with Federal buildings in three Federal regions. These buildings were systematically selected using OFEMP`s specifications; therefore, these data do not statistically represent all Federal buildings in the country. The purpose of the FBSS was threefold: (1) to understand the characteristics of Federal buildings and their energy use; (2) to provide a baseline in these three Federal regions to measure future energy use in Federal buildings as required in EPACT; and (3) to compare building characteristics and energy use with the data collected in the CBECS.

  20. Dipeptidylpeptidase-4 (DPP-4) inhibitors are favourable to glucagon-like peptide-1 (GLP-1) receptor agonists: yes.

    Science.gov (United States)

    Scheen, André J

    2012-03-01

    The pharmacological treatment of type 2 diabetes (T2DM) is becoming increasingly complex, especially since the availability of incretin-based therapies. Compared with other glucose-lowering strategies, these novel drugs offer some advantages such as an absence of weight gain and a negligible risk of hypoglycaemia and, possibly, better cardiovascular and β-cell protection. The physician has now multiple choices to manage his/her patient after secondary failure of metformin, and the question whether it is preferable to add an oral dipeptidylpeptidase-4 (DPP-4) inhibitor (gliptin) or an injectable glucagon-like peptide-1 (GLP-1) receptor agonist will emerge. Obviously, DPP-4 inhibitors offer several advantages compared with GLP-1 receptor agonists, especially regarding easiness of use, tolerance profile and cost. However, because they can only increase endogenous GLP-1 concentrations to physiological (rather than pharmacological) levels, they are less potent to improve glucose control, promote weight reduction ("weight neutrality") and reduce blood pressure compared to GLP-1 receptor agonists. Of note, none of the two classes have proven long-term safety and positive impact on diabetic complications yet. The role of DPP-4 inhibitors and GLP-1 receptor agonists in the therapeutic armamentarium of T2DM is rapidly evolving, but their respective potential strengths and weaknesses should be better defined in long-term head-to-head comparative controlled trials. Instead of trying to answer the question whether DPP-4 inhibitors are favourable to GLP-1 receptor agonists (or vice versa), it is probably more clinically relevant to look at which T2DM patient will benefit more from one or the other therapy considering all his/her individual clinical characteristics ("personalized medicine").

  1. Favouring NO over H2O2 production will increase Pb tolerance in Prosopis farcta via altered primary metabolism.

    Science.gov (United States)

    Zafari, Somaieh; Sharifi, Mohsen; Mur, Luis A J; Chashmi, Najmeh Ahmadian

    2017-08-01

    Reactive oxygen species (ROS) and nitric oxide (NO) are known in triggering defense functions to detoxify heavy metal stresses. To investigate the relevance of ROS production, Pb treatment (400µM) alone and in combination with 400µM sodium ascorbate (Asc: as H2O2 scavenger) were given to hydroponically grown Prosopis farcta seedlings over a time course of 72h. Data presented here indicate that, the low extent of H2O2 due to scavenging by ascorbate, together with high level of NO improved Pb+Asc- treated Prosopis growth. Following the evoked potential of both the signals, significant increases in phenolic acids; caffeic, ferulic and salicylic acid were observed with Pb treatment; which are consistent with observed increase in lignin content and consequently with growth inhibition. In contrast, Pb+Asc treatment induced more flavonoids (quercetin, kaempferol, luteolin), diminished phenolic acids contents and also lignin. Elicited expression rate of phenylalanine ammonia-lyase gene (PAL) and also its enzymatic activity verified the induced phenylpropanoid metabolism by Pb and Pb+Asc treatments. In comparison with Pb stress, Asc+Pb application induced the high expression of arginine decarboxylase gene (ADC), in polyamines biosynthesis pathway, and conducted the N flow towards polyamines and γ-amino butyric acid (GABA). Examining the impact on enzyme activities, catalase, and guaiacol peroxidase; Pb+Asc reduced activity but this increased ascorbate peroxidase, and aconitase activity. Our observations are consistent with conditions favouring NO production and reduced H2O2 can improve Pb tolerance via wide-ranging effects on a primary metabolic network. Copyright © 2017. Published by Elsevier Inc.

  2. APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein.

    Science.gov (United States)

    Chalmers, K; Wilcock, G K; Love, S

    2003-06-01

    The relative amounts of amyloid beta-protein (A beta) in cerebral blood vessels and parenchyma vary considerably amongst patients with Alzheimer's disease (AD). Although several mechanisms have been proposed to explain this variability, the underlying genetic and environmental determinants are still unclear, as are the functional consequences. Polymorphisms in APOE, the gene for apolipoprotein E (ApoE), influence the risk of developing AD and of deposition of A beta within the brain. We examined the relationship between the APOE genotype and the relative extent of accumulation of A beta as plaques within the cerebral parenchyma and in cortical blood vessels in the form of cerebral amyloid angiopathy (CAA), in autopsy brain tissue from 125 AD cases and from 53 elderly, neurologically normal controls of which 19 had CAA without other neuropathological features of AD. In the AD cases, we also assessed whether the severity of CAA was related to the age of onset and duration of dementia, risk factors for atherosclerotic vascular disease, and histologically demonstrable cerebral infarcts or foci of haemorrhage. The APOE genotype was determined by a standard polymerase chain reaction-based method. Paraffin sections of frontal, temporal and parietal lobes were immunolabelled for A beta and the parenchymal A beta load (total A beta minus vessel-associated A beta) was quantified by computer-assisted image analysis. CAA severity was scored for cortical and leptomeningeal vessels. The relevant clinical data were obtained from the database of the South West Brain Bank. In AD, we found the severity of CAA to be strongly associated with the number of epsilon 4 alleles (P possession of the APOE epsilon 4 allele favours vascular over parenchymal accumulation of A beta in AD. This may influence the pathogenesis of neurodegeneration in epsilon 4-associated AD.

  3. Class Teachers – Their Thinking and Reasoning in the Context of Creating a Favourable Classroom Social Climate by Means of the Methods of Personal and Social Education

    Directory of Open Access Journals (Sweden)

    Geršicová Zuzana

    2016-06-01

    Full Text Available The paper deals with class teachers’ thinking and reasoning processes and the possibilities of influencing teachers’ ability to create a favourable classroom social climate. This paper describes personal and social education as one of the means and methods of such influencing. The results of the research carried out indicate that teachers have a very high opinion regarding their ability to create a favourable classroom social climate. The issues of personal and social education in the work of a class teacher are the topic of the project KEGA 002DTI-4/2013 being solved by a team of professionals at Dubnica Institute of Technology in Dubnica nad Váhom.

  4. Distrito Federal, Brasil

    Directory of Open Access Journals (Sweden)

    Omar Alejandro Bravo

    2007-01-01

    Full Text Available Existen dos discursos contrapuestos al respecto de la cuestión del consumo de drogas: el tradicional, que considera sólo a las drogas ilegales, criminalizando al usuario y uno nuevo, denominado de reducción de daños, que no tiene como objetivo único su eliminación total, sino también la disminución de los efectos perjudiciales del mismo, priorizando así la salud de los sujetos y de la comunidad en general. En el marco particular de las instituciones públicas del Distrito Federal, Brasil, se analizan tanto el tipo de discursos predominantes en cada una de ellas, como las relaciones de poder que permiten y organizan. Se consideran en particular los niveles de gestión responsables por determinar y ejecutar las políticas de prevención y atención a las toxicomanías. El Análisis do Discurso, utilizado en este trabajo permite el análisis de las entrevistas realizadas en las instituciones. La discusión de este tema contribuye para pensar un cambio en las políticas públicas en esta área que permita el aprovechamiento integral de los recursos humanos e institucionales existentes.

  5. State-federal interactions in nuclear regulation

    Energy Technology Data Exchange (ETDEWEB)

    Pasternak, A.D.; Budnitz, R.J.

    1987-12-01

    The Atomic Energy Act of 1954 established, and later Congressional amendments have confirmed, that except in areas which have been explicitly granted to the states, the federal government possesses preemptive authority to regulate radiation hazards associated with the development and use of atomic energy. Since the passage of the original Act, numerous decisions by the courts have reaffirmed the legitimacy of federal preemption, and have defined and redefined its scope. In this study, the aim is to explore the underlying issues involved in federal preemption of radiation-hazard regulation, and to recommend actions that the Department of Energy and other agencies and groups should consider undertaking in the near term to protect the preemption principle. Appropriate roles of the states are discussed, as well as recent state-level activities and their rationale, and several current arenas in which state-federal conflicts about regulation of hazards are being played out. The emphasis here is on four particular arenas that are now important arenas of conflict, but the issues discussed are far broader in scope. These four arenas are: state-level moratorium activity; emergency planning for reactors; conflicts arising from state financial regulation; and inroads in federal preemption through litigation under state law.

  6. Sustainability in Brazilian Federal Universities

    Science.gov (United States)

    Palma, Lisiane Celia; de Oliveira, Lessandra M.; Viacava, Keitiline R.

    2011-01-01

    Purpose: The purpose of this paper is to identify the number of courses related to sustainability offered in bachelor degree programs of business administration in Brazilian federal universities. Design/methodology/approach: An exploratory research was carried out based on a descriptive scope. The process of mapping federal universities in Brazil…

  7. Deceptive Business Practices: Federal Regulations.

    Science.gov (United States)

    Rohrer, Daniel Morgan

    Federal regulations to prevent deceptive advertising seek to balance the advertiser's freedom of speech with protection of the consumer. This paper discusses what the Federal Trade Commission (FTC) has done to regulate advertising and evaluates the adequacy of its controls. The commission uses cease-and-desist orders, affirmative disclosure,…

  8. Indirect estimators in US federal programs

    CERN Document Server

    1996-01-01

    In 1991, a subcommittee of the Federal Committee on Statistical Methodology met to document the use of indirect estimators - that is, estimators which use data drawn from a domain or time different from the domain or time for which an estimate is required. This volume comprises the eight reports which describe the use of indirect estimators and they are based on case studies from a variety of federal programs. As a result, many researchers will find this book provides a valuable survey of how indirect estimators are used in practice and which addresses some of the pitfalls of these methods.

  9. Digital mapping of soil related common European biophysical criteria used for the identification of Less Favoured Areas in Hungary

    Science.gov (United States)

    Pásztor, László; Szabó, József; Bakacsi, Zsófia

    2010-05-01

    One of the main objectives of the EU's Common Agricultural Policy is to encourage maintaining agricultural production in less favoured areas (LFA) in order to sustain agricultural production and use natural resources, in such a way to secure both stable production and income to farmers and to protect the environment. LFA assignment has both ecological and severe economical aspects. Recently the delimitation of LFAs is suggested to be carried out by using common biophysical diagnostic criteria on low soil productivity and poor climate conditions all over Europe. The criterion system was elaborated by JRC and its operational implementation comes under member state competence. This process requires the existence of an adequate national spatial soil information system with appropriate data structure and spatial resolution as well as a proper methodology for its analysis. Hungary possesses an appropriate nationwide, 1:25,000 scale legacy data set originating from the national soil mapping project, which was initiated and led by Kreybig. This national survey was based on field and laboratory soil analyses and at the same time serving practical purposes. Its objective was the preparation of a map series which gives an insight to the geographical site and extent of soil conditions and soil properties for the production directing authorities, agricultural policy-makers, farmers, and the research institutes related to production problems. The similarity between the objectives of the old national mapping and those of the present European activities is remarkable. In the fifties, when the survey was completed, Hungary was the first in the world to have 1:25,000 scale soil information for the whole country. Overall chemical and physical soil properties of the soil root zone featuring soil patches were identified for croplands. Three characteristics were attributed to soil mapping units and displayed on the maps; further soil properties were determined and measured in soil

  10. Variation in the Use of Federal and State Civil Money Penalties for Nursing Homes

    Science.gov (United States)

    Harrington, Charlene; Tsoukalas, Theodore; Rudder, Cynthia; Mollot, Richard J.; Carrillo, Helen

    2008-01-01

    Purpose: The study examined factors associated with state variations in the use of federal and state civil money penalties (CMPs) for nursing homes. Design and Methods: We collected federal and state CMP data from state survey and certification agencies for 2004. We also used federal CMP data from the federal enforcement action database for…

  11. Monetary channels of social inclusion: a case study of basic income and the Caixa Econômica Federal in Brazil

    Directory of Open Access Journals (Sweden)

    Kurt Eberhart von Mettenheim

    2014-12-01

    Full Text Available This article reports evidence of new monetary channels for social inclusion involving basic income policies and the Caixa Econômica Federal, a Brazilian government savings bank. Since the Plano Real (Brazilian currency and the liberalization of banking in the 1990s, the realization of competitive advantages by the Caixa as social policy agent and the importance of citizenship cards differ from existing theories of bank change, financial inclusion and monetary policy. Multi-method research reveals the importance of 1 political theories of basic income, 2 conceptions of citizenship and social justice, and 3 a back to the future modernization of government banking. This provides alternatives to contemporary market-based banking theory, neo-liberal policies, private and non-governmental microfinance strategies, and theories in political economy about fiscal constraints to social policies. New monetary channels of change also suggest that zero sum theories about politics, monetary authority and social inclusion are amiss.

  12. International Implications: Are Polish Higher School Learners in Favour of Darwin's Theory of Evolution Being Taught in Primary and Secondary Schools?

    Science.gov (United States)

    Butler, Norman L.; Griffith, Kimberly Grantham; Kritsonis, William Allan

    2007-01-01

    The purpose of this article is to determine if Polish higher school learners are in favour of Darwin's evolutionary theory being included in the primary and secondary school curriculum. Thirty three students at AGH University of Science and Technology, Poland were surveyed, and the author found that all of them are in agreement with it. The…

  13. [Data protection and data access (I): federal data protection law and the social welfare code with reference to carrying out occupational medicine epidemiologic studies in Germany].

    Science.gov (United States)

    Weigelt, E; Scherb, H

    1992-11-01

    The regulations applicable to research in occupational epidemiology are the federal data protection (confidentiality) law (BDSG), the social welfare code (SGB), medical professional secrecy regulations and the federal statistics law (BStatG). The SGB, medical professional secrecy, and BStatG codes take precedence over BDSG rulings. This paper discusses BDSG and SGB. Medical professional secrecy and BStatG will be the topic of another publication (Datenschutz and Datenzugang II). The BDSG permits processing and utilization of personal data only if 1. this is permitted by BDSG or a law with higher priority, or 2. if the individual concerned has given her or his informed consent. According to the BDSG private research institutes can have access to personal data collected within non-public institutions only via section 28 (2) without consent of the individual. The "research paragraph" section 40 governs the processing and utilisation of personal data by research institutions. As a rule, the SGB permits access to epidemiological data sources only with the informed consent of the individuals concerned. The exception is section 75 SGBX. This paragraph permits disclosure of personal data without the individual's consent by the relevant public institution only if public interest considerably outweighs the private concerns. To our knowledge, however, this clause has had no practical significance. The concept of "informed consent" is discussed in detail, including the requirements for a legal form for informed consent. The legal codes of the BDSG, professional secrecy, and BStatG permit the transfer of personal data if the individuals concerned remain anonymous. This paper deals in detail with the concept of "anonymity".(ABSTRACT TRUNCATED AT 250 WORDS)

  14. Pregnancy may favour the development of severe autoimmune central diabetes insipidus in women with vasopressin cell antibodies: description of two cases.

    Science.gov (United States)

    Bellastella, Giuseppe; Bizzarro, Antonio; Aitella, Ernesto; Barrasso, Mariluce; Cozzolino, Domenico; Di Martino, Sergio; Esposito, Katherine; De Bellis, Annamaria

    2015-03-01

    Recently, an increased incidence of central diabetes insipidus (CDI) in pregnancy, and less frequently in the post partum period, has been reported, most probably favoured by some conditions occurring in pregnancy. This study was aimed at investigating the influence of pregnancy on a pre-existing potential/subclinical hypothalamic autoimmunity. We studied the longitudinal behaviour of arginine-vasopressin cell antibodies (AVPcAbs) and post-pituitary function in two young women with a positive history of autoimmune disease and presence of AVPcAbs, but without clinical CDI, and who became pregnant 5 and 7 months after our first observation. The behaviour of post-pituitary function and AVPcAbs (by immunofluorescence) was evaluated at baseline, during pregnancy and for 2 years after delivery. AVPcAbs, present at low/middle titres at baseline in both patients, showed a titre increase during pregnancy in one patient and after delivery in the other patient, with development of clinically overt CDI. Therapy with 1-deamino-8-d-arginine vasopressin (DDAVP) caused a prompt clinical remission. After a first unsuccessful attempt of withdrawal, the therapy was definitively stopped at the 6th and the 7th month of post partum period respectively, when AVPcAbs disappeared, accompanied by post-pituitary function recovery, persisting until the end of the follow-up. The determination of AVPcAbs is advisable in patients with autoimmune diseases planning their pregnancy, because they could be considered good predictive markers of gestational or post partum autoimmune CDI. The monitoring of AVPcAb titres and post-pituitary function during pregnancy in these patients may allow for an early diagnosis and an early replacement therapy, which could induce the disappearance of these antibodies with consequent complete remission of CDI.

  15. Report on Federal Individual Training Accounts.

    Science.gov (United States)

    President's Task Force on Federal Training Technology, Washington, DC.

    To explore options to establish Federal Individual Training Accounts (ITAs), a study reviewed Pennsylvania's Individual Learning Accounts, Cedar Company's Individual Learning Accounts, ITAs under the Workforce Investment Act, and the United Kingdom's Individual Learning Accounts. ITAs were defined as a base amount of resources--dollars or…

  16. Federal Fisheries Permit (FFP)/ Federal Processor Permit (FPP) Permit Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Federal Fisheries Permit (FFP) is required for vessels of the United States which are used to fish for groundfish in the Gulf of Alaska or Bering Sea and...

  17. Review of the Federal Mining Law. [German Federal Republic

    Energy Technology Data Exchange (ETDEWEB)

    Weller, H.

    1981-01-01

    The Federal Mining Law is a codification of mining law in the Federal Republic of Germany. It contains 178 paragraphs covering all aspects of prospecting and mining of mineral raw materials and related activities. The new law is to replace the former regional mining laws as well as most of the former Federal and regional regulations. All in all, 104 laws and regulations are repealed in sections 174 and 175. Basic principles of the former mining laws have been adhered to, e.g. mineral reserves do not come under the proprietory rights of the land owner, preventive monitoring of operations by means of operation plans, cession of territory under mining law, and the regulations concerning mining and land ownership. However, there are new details in the Federal Mining Law, in particular with regard to concessions and mining damage; this is reflected in a more complicated legal language.

  18. CD3+, CD4+ & CD8+ tumour infiltrating lymphocytes (TILs are predictors of favourable survival outcome in infiltrating ductal carcinoma of breast

    Directory of Open Access Journals (Sweden)

    Ankita Singh Rathore

    2014-01-01

    Full Text Available Background & objectives: Tumour infiltrating lymphocytes (TILs represent the host immune response against cancer cells associated with good or bad prognosis in different tumour types. This study was undertaken to evaluate the significance of CD3+, CD4+ and CD8+ TILs in breast cancer tissues in relation to clinico-pathological variables and survival outcome. Methods: Immunohistochemistry (IHC was performed with antibodies against CD3, CD4 and CD8 antigens on formalin-fixed paraffin-embedded tissue sections of 150 breast cancer patients. Intratumoural and stromal TIL counting was performed semiquantitatively. Results: The higher CD3+, CD4+ and CD8+ intratumoural and stromal counts showed independent and direct association with good prognosis. The prognostic predictor value of intratumoural counts was higher than stromal counts. The independent associations of intratumoural and stromal counts became more prominent when adjusted with stage and grade, respectively. Among intratumoural counts, the high (++/+++ CD4+ count (OR=3.85, 95% CI=3.28-16.71, P<0.001 showed the highest survival followed by CD3+ (OR=2.70, 95% CI=1.76-8.30, P=0.001 and CD8+ (OR=2.58, 95% CI=1.55-5.86, p0 =0.001 the least when compared to respective low (+ counts. In contrast, among stromal counts, the high CD8+ count (OR=3.13, 95% CI=2.20-9.57, p0 <0.001 showed the highest survival followed by CD4+ (OR=3.02, 95% CI=2.07-8.89, p0 <0.001 and CD3+ (OR=2.45, 95% CI=1.53-6.73, p0 =0.002 the least. Interpretation & conclusions: Our results suggest that intratumoural CD4+ and stromal CD8+ counts by immunohistochemistry may serve as an independent prognosticator for favourable outcome in breast cancer.

  19. Federalism and technological change in blood products.

    Science.gov (United States)

    Taylor, Mark Zachary

    2009-12-01

    Recent research has shown how federalism affects health care finance, health care reform, and health policy innovation. The purpose of this article is to extend this research program to study the linkages between federalism and technological change. It does so using comparative case studies spanning five countries to examine innovation and diffusion of two blood technologies-enzyme-linked immunosorbent assays (ELISA blood tests) and heat treatment-in response to the threat to the blood supply posed by HIV during the 1980s. Prior research has produced three contradictory models of the federalism-innovation relationship. This article attempts to resolve these contradictions, posits new hypotheses, and highlights sources of omitted variable bias that have important implications for understanding technological change. The case studies show that overall decentralization, rather than federalism alone, aids technological progress by allowing its supporters to "venue shop" around political resistance. Decentralization also makes the state less vulnerable to capture by status-quo interest groups. Moreover, political decentralization may have a positive effect on technological diffusion, but a far weaker effect on innovation. Thus, prior research that conflates these two effects should be revisited.

  20. Federated Spatial Databases and Interoperability

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    It is a period of information explosion. Especially for spatialinfo rmation science, information can be acquired through many ways, such as man-mad e planet, aeroplane, laser, digital photogrammetry and so on. Spatial data source s are usually distributed and heterogeneous. Federated database is the best reso lution for the share and interoperation of spatial database. In this paper, the concepts of federated database and interoperability are introduced. Three hetero geneous kinds of spatial data, vector, image and DEM are used to create integrat ed database. A data model of federated spatial databases is given

  1. Attributes of the Federal Energy Management Program's Federal Site Building Characteristics Database

    Energy Technology Data Exchange (ETDEWEB)

    Loper, Susan A.; Sandusky, William F.

    2010-12-31

    Typically, the Federal building stock is referred to as a group of about one-half million buildings throughout the United States. Additional information beyond this level is generally limited to distribution of that total by agency and maybe distribution of the total by state. However, additional characterization of the Federal building stock is required as the Federal sector seeks ways to implement efficiency projects to reduce energy and water use intensity as mandated by legislation and Executive Order. Using a Federal facility database that was assembled for use in a geographic information system tool, additional characterization of the Federal building stock is provided including information regarding the geographical distribution of sites, building counts and percentage of total by agency, distribution of sites and building totals by agency, distribution of building count and floor space by Federal building type classification by agency, and rank ordering of sites, buildings, and floor space by state. A case study is provided regarding how the building stock has changed for the Department of Energy from 2000 through 2008.

  2. Volpentest HAMMER Federal Training Center

    Data.gov (United States)

    Federal Laboratory Consortium — HAMMER stands for Hazardous Materials Management and Emergency Response, and was named for Sam Volpentest, a long-time community leader and advocate of the Hanford...

  3. Protected Areas - Protected Federal Lands

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — The Federal Lands data consists of land areas that are run and maintained by U.S. Governmental authorities and are considered protected.The Department of Natural...

  4. Federal Energy Management Program Overview

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-08-05

    Brochure offers an overview of the Federal Energy Management Program (FEMP), which provides agencies and organizations with the information, tools, and assistance they need to achieve their energy-related requirements and goals through specialized initiatives.

  5. Federal Technology Transfer Act (FTTA)

    Science.gov (United States)

    EPA's Federal Technology Transfer Act (FTTA) is a mechanism with which EPA can patent its inventions and license them to companies, through which innovative technologies can enter the marketplace to improve the environment and human health.

  6. VT Federal Aid Urban Boundaries

    Data.gov (United States)

    Vermont Center for Geographic Information — Federal Aid Urban boundaries are defined based on US Census data. The roadways within these boundaries have urban classifications. These FAU boundaries were updated...

  7. Department of Biological Sciences, Federal

    African Journals Online (AJOL)

    USER

    2015-05-07

    May 7, 2015 ... Department of Biological Sciences, Federal University of Agriculture, Abeokuta, Nigeria ... concentrations in the parent soil under Gmelina plantation were significantly higher (p 0.05) ... In spite of the many benefits that.

  8. Monitoring of the xrootd federations

    CERN Document Server

    CERN. Geneva

    2013-01-01

    Construction of the data federations and understanding the impact of the new approach to data management on user analysis requires complete and detailed monitoring. Monitoring functionality should cover the status of all components of the federated storage, measuring data traffic and data access performance, as well as being able to detect any kind of inefficiencies and to provide hints for resource optimization and effective data distribution policy. Data mining of the collected monito...

  9. Federal technology policy in transition

    Energy Technology Data Exchange (ETDEWEB)

    Carnes, K.H.

    1995-12-31

    This paper discusses federal energy and environmental policies and their impact on the U.S. economy. A brief history of the federal government`s role in developing scientific and technological infrastructure is given. Current trends in technology are summarized, with an emphasis on global aspects, and their impact on the economy is discussed. The need for a national technology policy, including continued research and development funding, is discussed and key elements of such a policy are outlined.

  10. Estudo descritivo de alterações posturais sagitais da coluna lombar em escolares da rede federal de ensino de Florianópolis Descriptive study of sagittal lumbar spine changes in students of the federal educational system of Florianópolis

    Directory of Open Access Journals (Sweden)

    Susane Graup

    2010-01-01

    Full Text Available OBJETIVO: O objetivo deste estudo foi analisar a prevalência de alterações posturais sagitais na coluna lombar e fatores associados em escolares da Rede Federal de Ensino de Florianópolis. MÉTODOS: Foram avaliados 288 adolescentes (156 do sexo masculino e 132 do feminino, na faixa etária dos 15 aos 18 anos, estudantes da Rede Federal de Ensino de Florianópolis/SC. Para o levantamento dos dados utilizou-se: fotogrametria seguindo protocolo específico para avaliação postural e questionário para identificar a prevalência de quadros de dor, frequência e atividades que desencadeavam o problema. Na análise de dados utilizou-se de estatística descritiva, teste t de Student para amostras independentes, Qui-quadrado e regressão de Poisson, adotando a significância de 0,05 em todos os testes. RESULTADOS: A prevalência de dor lombar foi de 49,3%, apresentando uma frequência semanal em 43,1% dos avaliados. A prevalência de desvios foi de 53,8%, sendo que 90,9% corresponderam à retificação da curvatura lombar, acometendo mais o sexo masculino. Foi encontrada diferença significativa no ângulo lombar entre os sexos, sendo que o grupo masculino apresentou razões de prevalência superiores de desvios posturais. A variável dor lombar não apresentou associação com desvios posturais sagitais. CONCLUSÃO: As prevalências de dor e desvios posturais na coluna lombar foram elevadas, sendo que a relação entre essas variáveis não se apresentou de forma significativa. As principais causas de dor lombar foram a prática de esportes ou atividades vigorosas e a permanência durante longos períodos de tempo na posição sentada.OBJECTIVE: The purpose of this study was to assess the prevalence of sagittal lumbar spine changes and associated factors in students of the federal educational system of Florianópolis. METHODS: 288 adolescents (156 males and 132 females, aged from 15 to 18 years, students of the Florianópolis' federal school took

  11. 30 CFR 917.30 - State-Federal cooperative agreement.

    Science.gov (United States)

    2010-07-01

    ... Federal Water Pollution Control Act, 33 U.S.C. 1251 et seq., and implementing regulations. 11. The... Federal definitions, the definitions used in the approved State Program will apply except in the case of a..., laboratories and facilities to perform all inspections, investigations, studies, tests and analyses that...

  12. 78 FR 41183 - Federal Aviation Administration

    Science.gov (United States)

    2013-07-09

    ... Federal Aviation Administration Meeting: RTCA Program Management Committee AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Notice of RTCA Program Management.... Paige Williams, Management Analyst, NextGen, Business Operations Group, Federal Aviation...

  13. 75 FR 6433 - Federal Aviation Administration

    Science.gov (United States)

    2010-02-09

    ... Federal Aviation Administration Notice of Availability of a Draft Environmental Assessment and Public...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Availability of a Draft Environmental... Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA) proposes to fund, construct,...

  14. 76 FR 78966 - Federal Aviation Administration

    Science.gov (United States)

    2011-12-20

    ... Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on the noise compatibility...

  15. 77 FR 64837 - Federal Aviation Administration

    Science.gov (United States)

    2012-10-23

    ... Federal Aviation Administration Fourth Meeting: RTCA Special Committee 227, Standards of Navigation Performance AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... 15, 2012. Kathy Hitt, Management Analyst, Business Operations Group, Federal Aviation...

  16. 76 FR 2745 - Federal Aviation Administration

    Science.gov (United States)

    2011-01-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Eighty-Fourth Meeting: RTCA Special Committee 159: Global Positioning System (GPS) AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special...

  17. 76 FR 77302 - Federal Transit Administration

    Science.gov (United States)

    2011-12-12

    ... Federal Transit Administration FY 2011 Discretionary Sustainability Funding Opportunity; Transit... Discretionary Bus and Bus Facilities Program AGENCY: Federal Transit Administration (FTA), DOT. ACTION: FTA...'s (DOT) Federal Transit Administration (FTA) announces the selection of Fiscal Year (FY)...

  18. OBSERVING OF RADIOACTIVE CAESIUM 137Cs VALUE IN BEEF MEAT (CZECH PIED CATTLE IN LESS-FAVOURED AREAS OF THE CZECH REPUBLIC

    Directory of Open Access Journals (Sweden)

    Ivan Holko

    2012-02-01

    Full Text Available Value of radiocaesium 137Cs as one of Risk Factors in beef meat is very important for human health. Beef meat (m. longissimus lumborum et thoracis from Czech Pied cattle in two less-favoured areas located more then 500 meters above sea level (Bohemian Forest Bohemian and Moravian Highland was dependent on Sex (decrease by female, increase by male, P<1.10-6 and on area (P<1.10-6. Value of radiocaesium 137Cs in beef meat ( = 0,42 Bq.kg-1; sx = 0,28 was less then food standard (600 Bq.kg-1. This observed result are responding to finding another authors and could be used for next more detailed research in optimal utilization of Czech Pied cattle in less-favoured areas.

  19. Favourable effect of TNF-alpha inhibitor (infliximab) on Blau syndrome in monozygotic twins with a de novo CARD15 mutation

    DEFF Research Database (Denmark)

    Milman, Nils; Andersen, Claus B; Hansen, Annette

    2006-01-01

    quality of life. At follow up at 20 years of age (after 2-5 years of infliximab treatment) the twins had an almost normal physical appearance and a normal psychomotoric development, indicating a favourable short-term prognosis of the disease. Blau syndrome has pathologic, clinical and therapeutic features...... in common with sarcoidosis, but rarely involves the lungs or other parenchymatous organs. In children, discrimination between early onset sarcoidosis and Blau syndrome should include a CARD15 mutation analysis....

  20. The most-favoured-nation clause in tax treaties: tool for potential reduction of withholding income tax applicable to Chile and Canada

    OpenAIRE

    Renée Antonieta Villagra Cayamana; Jorge Antonio Villagra Cayamana

    2013-01-01

    Tax treaties to avoid the double taxation signed by a country have consequences for the future, but they can also modify the terms of treaties that are already in force, in case these contain most-favoured-nation clauses. In this line, taxpayers and companies, particularly, as well as the Tax Administration must be alert, regarding topotential modifications of the terms of the Peruvian tax treaties already in force; mainly about the withholding tax rate applied to royalties in the Convention ...

  1. Factors fragmenting the Russian Federation

    Energy Technology Data Exchange (ETDEWEB)

    Brown, E.

    1993-10-06

    This paper examines the factors that threaten the future of the Russian Federation (RF). The observations are based on a study that focused on eight republics: Mordova, Udmurtia, Tatarstan, Mari El, Bashkortostan, Kabardino-Balkaria, Buryatia, and Altay Republic. These republics were selected for their geographic and economic significance to the RF. Tatarstan, Bashkortostan, Udmurtia, and Mari El are located on important supply routes, such as the Volga River and the trans-Siberian railroad. Some of these republics are relatively wealthy, with natural resources such as oil (e.g., Tatarstan and Bashkortostan), and all eight republics play significant roles in the military-industrial complex. The importance of these republics to the RF contrasts to the relative insignificance of the independence-minded Northern Caucasus area. The author chose not to examine the Northern Caucasus region (except Kabardino-Balkaria) because these republics may have only a minor impact on the rest of the RF if they secede. Their impact would be minimized because they lie on the frontiers of the RF. Many Russians believe that {open_quotes}it might be best to let such a troublesome area secede.{close_quotes}

  2. Changes in vector species composition and current vector biology and behaviour will favour malaria elimination in Santa Isabel Province, Solomon Islands

    Directory of Open Access Journals (Sweden)

    Beebe Nigel W

    2011-09-01

    Full Text Available Abstract Background In 2009, Santa Isabel Province in the Solomon Islands embarked on a malaria elimination programme. However, very little is known in the Province about the anopheline fauna, which species are vectors, their bionomics and how they may respond to intensified intervention measures. The purpose of this study was to provide baseline data on the malaria vectors and to ascertain the possibility of successfully eliminating malaria using the existing conventional vector control measures, such as indoor residual spraying (IRS and long-lasting insecticidal nets (LLIN. Methods Entomological surveys were undertaken during October 2009. To determine species composition and distribution larval surveys were conducted across on the whole island. For malaria transmission studies, adult anophelines were sampled using human landing catches from two villages - one coastal and one inland. Results Five Anopheles species were found on Santa Isabel: Anopheles farauti, Anopheles hinesorum, Anopheles lungae, Anopheles solomonis, and Anopheles nataliae. Anopheles hinesorum was the most widespread species. Anopheles farauti was abundant, but found only on the coast. Anopheles punctulatus and Anopheles koliensis were not found. Anopheles farauti was the only species found biting in the coastal village, it was incriminated as a vector in this study; it fed early in the night but equally so indoors and outdoors, and had a low survival rate. Anopheles solomonis was the main species biting humans in the inland village, it was extremely exophagic, with low survival rates, and readily fed on pigs. Conclusion The disappearance of the two major vectors, An. punctulatus and An. koliensis, from Santa Isabel and the predominance of An. hinesorum, a non-vector species may facilitate malaria elimination measures. Anopheles farauti was identified as the main coastal vector with An. solomonis as a possible inland vector. The behaviour of An. solomonis is novel as it has

  3. The most-favoured-nation clause in tax treaties: tool for potential reduction of withholding income tax applicable to Chile and Canada

    Directory of Open Access Journals (Sweden)

    Renée Antonieta Villagra Cayamana

    2013-07-01

    Full Text Available Tax treaties to avoid the double taxation signed by a country have consequences for the future, but they can also modify the terms of treaties that are already in force, in case these contain most-favoured-nation clauses. In this line, taxpayers and companies, particularly, as well as the Tax Administration must be alert, regarding topotential modifications of the terms of the Peruvian tax treaties already in force; mainly about the withholding tax rate applied to royalties in the Convention subscribed with Chile and the withholding tax rates applied to dividends, interests and royalties in the Convention subscribed with Canada, taking into account that both of the mentioned tax treaties contain most-favoured-nation clauses for those kind of income. The Ministry of Economy, as the entity in charge of negotiations of the bilateral conventions, according to Law Decree 25883, has the responsibility of negotiating future treaties with full knowledge that the terms to be included could also cause the effect to decrease the withholding tax rates of the income tax in respect to conventions already in effect, as a consequence of the most-favoured-nation clause they contain.

  4. Cooperation in USDA studies and evaluations, and full use of federal funds in nutrition assistance programs nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010, Public Law 111-296. Final Rule.

    Science.gov (United States)

    2011-06-29

    This final rule incorporates into the regulations governing the Programs authorized under the Richard B. Russell National School Lunch Act (NSLA) and the Child Nutrition Act of 1966 (CNA) two nondiscretionary provisions of the Healthy, Hunger-Free Kids Act of 2010 (HHFK Act). The HHFK Act requires State and local cooperation in Department of Agriculture studies and evaluations related to Programs authorized under the NSLA and the CNA. The HHFK Act also amends the NSLA to stipulate that Federal funds must not be subject to State budget restrictions or limitations, including hiring freezes, work furloughs, and travel restrictions. This final rule amends regulations for the National School Lunch Program; the Special Milk Program for Children; the School Breakfast Program; the Summer Food Service Program; the Child and Adult Care Food Program; State Administrative Expense Funds ; the Special Supplemental Nutrition Program for Women, Infants and Children; and the WIC Farmers' Market Nutrition Program. These provisions will strengthen program integrity by ensuring that sufficient data is made available for studies and evaluations. Additionally, exempting Federal funds from State budgetary restrictions or limitations is intended to increase the ability of State agencies to administer USDA's nutrition assistance programs effectively.

  5. 77 FR 47374 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Science.gov (United States)

    2012-08-08

    ... Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal Direct... William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education Loan (FFEL) Programs may... of Collection: William D. Ford Federal Direct Loan (Direct Loan) Program/Federal Family Loan...

  6. Undergraduates Prefer Federated Searching to Searching Databases Individually. A Review of: Belliston, C. Jeffrey, Jared L. Howland, & Brian C. Roberts. “Undergraduate Use of Federated Searching: A Survey of Preferences and Perceptions of Value-Added Functionality.” College & Research Libraries 68.6 (Nov. 2007: 472-86.

    Directory of Open Access Journals (Sweden)

    Genevieve Gore

    2008-09-01

    number of citations. Data were then analysed using ANOVA and MANOVA. Finally, librarians at the ACRL 13th NationalConference Presentation were polled about their perceptions of the time savings of federated searching, whether the method meets undergraduates’ information needs, undergraduate preference for searching, and the quality of citations found.Main Results – Seventy percent of all participants preferred federated searching. For all schools combined, there was nostatistically significant difference between the average time taken using federated searching (20.34 minutes vs. non-federated searching (22.72 minutes. For all schools combined, there was a statistically significant difference in satisfaction of results favouring federated searching (5.59/7 vs. 4.80/7 for non-federated searching, α = .05. According to the librarian-created rubric, citations retrieved from federated searching were a statistically significant 6% lower in quality than citations retrieved from non-federated searching (α = .05. The faculty-approved rubric did not detect a difference in the quality of the citations retrieved using the 2 methods. Librarians’ perceptions as assessed at the ACRL 13thNational Conference Presentation generally matched the authors’findings.Conclusion – Overall, students in this study preferred federated searching, were more satisfied with the results of federated searching, and saved time (although the savings were not statistically significant. The quality of citations retrieved via both methods was judged to be similar. The study provides useful information for librarians interested in users’ experiences and perceptions of federated searching, and indicates future studies worth conducting.

  7. Práticas e significados de saúde bucal: um estudo qualitativo com mães de crianças atendidas na Universidade Federal de Santa Catarina Practices and meanings of oral health: a qualitative study with mothers of children assisted at the Federal University of Santa Catarina

    Directory of Open Access Journals (Sweden)

    Ana Carolina Couto Robles

    2010-10-01

    Full Text Available Este estudo objetivou conhecer práticas e significados de saúde bucal de mães de crianças atendidas em clínicas de odontopediatria da Universidade Federal de Santa Catarina. O método qualitativo tipo estudo de caso foi utilizado e os dados foram coletados por meio de entrevista semiestruturada. A população estudada constituiu-se por sete mães que levavam seus filhos para atendimento odontológico na universidade. Observou-se que experiências negativas vivenciadas em tratamentos odontológicos anteriores, dificuldades financeiras e gravidez influenciaram-nas na busca e adesão a tratamentos. A procura pelo dentista ocorreu, principalmente, para realização de procedimentos curativos. As mães cuidam dos dentes de seus filhos por considerarem tais cuidados responsabilidade materna, para prevenir cárie e suas consequências, evitar gastos com tratamentos onerosos e que as crianças passem por experiências desagradáveis com dentistas. As fontes de informação citadas sobre os cuidados com a boca foram dentistas, médicos, enfermeiras, escolas, veículos de comunicação em massa e acadêmicos de odontologia. Apesar de desejarem cuidar da saúde de seus filhos de maneira adequada, nem sempre elas têm condições econômicas e sociais favoráveis para colocar os ensinamentos em prática.This research aimed to know oral health practices and meanings of mothers whose children were attended in the dental pediatric clinics of the Federal University of Santa Catarina. The qualitative method, case study, was used and data were collected by semi-structured interview. The studied population consisted of seven mothers that took their children to odontologic attendance at the university. It was observed that despite previous negative odontologic experiences, economic difficulties and pregnancy have also influenced those mothers to look for and adhere to dental care. The dental visits occurred, mostly, for curative assistance. The mothers took

  8. Federal Personnel: Federal/Private Sector Pay Comparisons

    Science.gov (United States)

    1994-12-01

    Federal Employees Covered by Social Security, December 1984. ^This finding is based on a comparison of employer cost associated with the various...and gender. Specifically, ’For a further discussion, see Robert Willis, "Wage Determinante : A Survey and ReinterpreteÜori of Human Capital Earnings

  9. Federation for a Secure Enterprise

    Science.gov (United States)

    2016-09-10

    Countering the Futility of Network Security ," Air and Space Power Journal, Sep-Oct 2015, Vol 29, No.5, pg. 4. [8]. Coimbatore Chandersekaran and William...I N S T I T U T E F O R D E F E N S E A N A L Y S E S Federation for a Secure Enterprise William R. Simpson September 10, 2016 Approved for...252.227-7013 (a)(16) [Jun 2013]. Federation for a Secure Enterprise1 William R. Simpson and Kevin E. Foltz Institute for Defense Analyses

  10. Satisfação com o atendimento odontológico: estudo qualitativo com mães de crianças atendidas na Universidade Federal de Santa Catarina Satisfaction with dental care: qualitative study of the mothers of children treated at the Santa Catarina Federal University, Brazil

    Directory of Open Access Journals (Sweden)

    Ana Carolina Couto Robles

    2008-02-01

    Full Text Available Esta pesquisa objetivou conhecer a percepção de mães em relação ao atendimento odontológico prestado em clínicas de odontopediatria da Universidade Federal de Santa Catarina (UFSC, bem como sua concepção sobre como seria o dentista "ideal". O método utilizado foi o qualitativo, tipo estudo de caso. A coleta de dados foi feita através de entrevista semi-estruturada e a população estudada constituiu-se de sete mães de crianças atendidas em clínicas de odontopediatria da UFSC. Observou-se que, para as mães entrevistadas, o dentista ideal deveria reunir habilidades afetivas, psicomotoras e cognitivas, tais como: gostar do que faz, ser atencioso e amigável, fornecer informações claras sobre saúde bucal, resolver os problemas bucais do paciente e manter-se atualizado. Os aspectos interpessoais foram fundamentais para a satisfação com o atendimento na universidade, além da capacidade técnica dos alunos e a facilidade para conseguir uma vaga no serviço de odontopediatria. Sugere-se maior entendimento, por parte dos profissionais, dos aspectos que envolvem a relação dentista-paciente, de maneira a associar fatores afetivos aos cognitivos e psicomotores no dia-a dia da prática odontológica.This survey examines perceptions among mothers of the treatment provided through pediatric dentistry clinic at the Santa Catarina Federal University and their concept of the 'ideal' dentist, using the qualitative (case study method. Collected through semi-structured interviews with seven mothers of children treated at this pediatric dentistry clinic, the data showed that these mothers felt the 'ideal' dentist should blend affective, psychomotor and cognitive abilities: enjoying his work; being attentive and friendly; providing clear information about oral health; resolving oral problems presented by patients; and keeping up-to-date. Interpersonal aspects were crucial factors for satisfaction with the treatment provided at the University, in

  11. 49 CFR 1325.3 - Federal office.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Federal office. 1325.3 Section 1325.3... FEDERAL OFFICE OR THEIR REPRESENTATIVES § 1325.3 Federal office. For the purposes of this section, Federal office means the office of President or Vice President of the United States; or of Senator...

  12. 14 CFR Special Federal Aviation... - 2

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false 2 Federal Special Federal Aviation Regulation No. 50 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Special Federal Aviation Regulation No. 50-2...

  13. 14 CFR Special Federal Aviation... - 1

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false 1 Federal Special Federal Aviation Regulation No. 100 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Special Federal Aviation Regulation No...

  14. Federal Depository Libraries and Librarianship.

    Science.gov (United States)

    Illinois Libraries, 1986

    1986-01-01

    Reports results of 1985 survey of federal depository libraries in Illinois, including the arrangement of collections and bibliographic access, acquisitions and weeding, services and equipment, library and librarian cooperation, documents staff, State Plan and State Plan Coordinating Council, online systems and access to government documents, and…

  15. Federalization of Education in Chihuahua

    Science.gov (United States)

    Marak, Andrae M.

    2005-01-01

    This article examines the politics behind the initial centralization of primary education in Chihuahua, Mexico during the 1920s and 1930s. The article argues that the centralization of primary education was one of many tools used by the federal government to consolidate its power in the wake of the Mexican Revolution (1910-1917) and create a…

  16. THE PREVALENCE OF ELEVATED LEVELS OF C-REACTIVE PROTEIN AND ITS ASSOCIATION WITH TRADITIONAL RISK FACTORS AND MORBIDITY AMONG RESIDENTS OF THE RUSSIAN FEDERATION (ACCORDING TO THE ESSE-RF STUDY

    Directory of Open Access Journals (Sweden)

    S. E. Evstifeeva

    2015-09-01

    Full Text Available Aim. To study the association of high-sensitivity C-reactive protein (hsCRP level with socio-demographic, behavioral and traditional risk factors in different regions of the Russian Federation (RF.Material and methods. Data of the multicenter epidemiological study of cardiovascular disease in different regions of the Russian Federation (ESSE-RF were used. Representative sample of the unorganized male and female population aged 25-64 from 6 regions of the Russian Federation was drown. 3407 men and 6354 women (n=9761 were included into the study. Standard questionnaire was applied in all subjects. Gender, age, level of education, place of residence and region of residence, traditional risk factors and diseases were analyzed. HsCRP level (level ≥3.0 mg/l was defined as elevated one was evaluated to detect of indolent inflammation.Results. HsCRP levels in women was significantly higher compared to males (p<0.005. The average prevalence of elevated hsCRP in the regions was 24.2%, for men - 21.4%, and for women - 25.7% (p<0.005. Significant age-related dynamics of hsCRP (p<0.0001 was found. The average level of hsCRP was significantly lower (p<0.0001 in a cohort of persons with higher education against these with lower level of education. Level of hsCRP as well as prevalence of elevated hsCRP level were higher in villagers than this in the urban population (p<0.05. Prevalence of elevated hsCRP in patients with traditional risk factors after adjustment for sex, age, and region of residence showed that the elevated hsCRP was mostly associated with metabolic factors and diseases that were characterized by systemic inflammation.Conclusion. Elevated level of hsCRP (≥3.0 mg/l was significantly associated with female gender, with an older, less educated, and smoking population of Russians. After the multivariate adjustment there remained significant associations (p<0.0001 of elevated hsCRP level with obesity, including abdominal obesity, hyperglycemia

  17. Federal Grant "Seed Money"--Sprouted, Growing and Blooming in the Kansas Sandhills: Interdisciplinary Studies--Their "Place in the Sun."

    Science.gov (United States)

    Bogner, Donna

    The Outdoor Research Project of Hutchinson Senior High School in Hutchinson, Kansas, was funded in 1977 to conduct a scientific baseline study of an outdoor education center and a state park. Gifted students used initial limnology tests, fish population studies, and groundcover analyses to produce management recommendations and a computer…

  18. 電子資源整合查詢系統使用者接受度與使用行為之研究 A Study on User Perceptions and User Behavior of an Online Federated Search System

    Directory of Open Access Journals (Sweden)

    Ching-Yi Lee

    2012-03-01

    Full Text Available 本研究探討使用者對電子資源整合查詢系統的認知情形、系統接受度與使用行為。本研究以科技接受模式為框架,發展適用於評量使用者對整合查詢系統之接受度與使用行為的問卷,繼而以交大圖書館之MetaLib系統為個案,探討該館讀者使用整合查詢系統的接受程度與使用行為,探討影響整合查詢系統使用行為的相關因素,分析本研究所提出之科技接受模式外部變項「教育訓練認知」和該模式之「易用性認知」、「有用性認知」、「態度」、「使用意願」及「使用行為」等變項間的關係。研究結果發現,整合查詢系統有助於使用者找尋所需的資源,使用者對於整合查詢系統功能的認同程度頗高,絕大多數會推薦他人使用該系統,但在系統功能、介面設計與使用者教育訓練方面仍有改善空間。結果證實教育訓練認知、有用性認知、易用性認知、態度、使用意願確實會影響使用者對整合查詢系統之認知情形、系統接受度與使用行為。This study aims at investigating the perceptions, acceptance and usage behavior of users on federated search systems. The research method involved the development of a questionnaire on users’ satisfaction and acceptance of federated search systems based on Technology Acceptance Model (TAM. The federated search system implemented in National Chiao Tung University (NCTU was used as a case system. In addition to the six constructs of TAM, i.e. perceived ease of use, perceived usefulness, attitude, behavioral intention, and actual use, the construct user training is proposed as the external variable. After the development of the questionnaire was finished, an online survey was conducted. 403 effective responses were collected. Through Pearson-product moment correlation and structural equation modeling, the correlation and causal relationships between factors which influence the

  19. Using Xrootd to Federate Regional Storage

    Science.gov (United States)

    Bauerdick, L.; Benjamin, D.; Bloom, K.; Bockelman, B.; Bradley, D.; Dasu, S.; Ernst, M.; Gardner, R.; Hanushevsky, A.; Ito, H.; Lesny, D.; McGuigan, P.; McKee, S.; Rind, O.; Severini, H.; Sfiligoi, I.; Tadel, M.; Vukotic, I.; Williams, S.; Würthwein, F.; Yagil, A.; Yang, W.

    2012-12-01

    While the LHC data movement systems have demonstrated the ability to move data at the necessary throughput, we have identified two weaknesses: the latency for physicists to access data and the complexity of the tools involved. To address these, both ATLAS and CMS have begun to federate regional storage systems using Xrootd. Xrootd, referring to a protocol and implementation, allows us to provide data access to all disk-resident data from a single virtual endpoint. This “redirector” discovers the actual location of the data and redirects the client to the appropriate site. The approach is particularly advantageous since typically the redirection requires much less than 500 milliseconds and the Xrootd client is conveniently built into LHC physicists’ analysis tools. Currently, there are three regional storage federations - a US ATLAS region, a European CMS region, and a US CMS region. The US ATLAS and US CMS regions include their respective Tier 1, Tier 2 and some Tier 3 facilities; a large percentage of experimental data is available via the federation. Additionally, US ATLAS has begun studying low-latency regional federations of close-by sites. From the base idea of federating storage behind an endpoint, the implementations and use cases diverge. The CMS software framework is capable of efficiently processing data over high-latency links, so using the remote site directly is comparable to accessing local data. The ATLAS processing model allows a broad spectrum of user applications with varying degrees of performance with regard to latency; a particular focus has been optimizing n-tuple analysis. Both VOs use GSI security. ATLAS has developed a mapping of VOMS roles to specific file system authorizations, while CMS has developed callouts to the site's mapping service. Each federation presents a global namespace to users. For ATLAS, the global-to-local mapping is based on a heuristic-based lookup from the site's local file catalog, while CMS does the mapping

  20. Opportunities for the compensation of the fluctuation feed-in from renewable energy sources. Study commissioned by the German Renewable Energy Federation; Moeglichkeiten zum Ausgleich Fluktuierender Einspeisungen aus Erneuerbaren Energien. Studie im Auftrag des Bundesverbandes Erneuerbare Energie

    Energy Technology Data Exchange (ETDEWEB)

    Krzikalla, Norbert; Achner, Siggi; Bruehl, Stefan [BET Buero fuer Energiewirtschaft und technische Planung GmbH, Aachen (Germany)

    2013-05-01

    The platform 'system transformation' of the German Renewable Energy Federation (Berlin, Federal Republic of Germany) accompanies the forthcoming restructuring of the energy supply towards 100 percent renewable energy. The previous discussions of this platform provided two results: the fluctuating renewable energies must be placed at the center of considerations in order to enable a sustainable system design and market design. Furthermore, the question of how the fluctuating feed-in from renewable energy sources can be compensated has to be answered. Under this aspect, the contribution under consideration reports on these compensation options. There are different flexibility options available in order to create a safe, environmentally sustainable and affordable energy system.

  1. Informal caregiving as a risk factor for type 2 diabetes in individuals with favourable and unfavourable psychosocial work environments

    DEFF Research Database (Denmark)

    Mortensen, J; Clark, Adrian J L; Lange, T.

    2017-01-01

    Longitudinal Occupational Survey of Health (SLOSH) and the British Whitehall II study-a total of 21,243 study subjects. Informal caregiving was defined as unpaid care for a closely related person. Job strain was assessed using the demand-control model, and questions on co-worker and supervisor support were...

  2. High Level Architecture (HLA) federation with Umbra and OPNET federates.

    Energy Technology Data Exchange (ETDEWEB)

    Oppel, Fred John III; Hart, Brian; Van Leeuwen, Brian P.

    2004-03-01

    Network-centric systems that depend on mobile wireless ad hoc networks for their information exchange require detailed analysis to support their development. In many cases, this critical analysis is best provided with high-fidelity system simulations that include the effects of network architectures and protocols. In this research, we developed a high-fidelity system simulation capability using an HLA federation. The HLA federation, consisting of the Umbra system simulator and OPNET Modeler network simulator, provides a means for the system simulator to both affect, and be affected by, events in the network simulator. Advances are also made in increasing the fidelity of the wireless communication channel and reducing simulation run-time with a dead reckoning capability. A simulation experiment is included to demonstrate the developed modeling and simulation capability.

  3. Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

    Directory of Open Access Journals (Sweden)

    Mehl Erika

    2007-11-01

    Full Text Available Abstract Background Kisspeptins and their G-protein coupled receptor, GPR54 are required for GnRH release and have been associated with anti-metastatic tumour cell behaviour in model systems. The latter might suggest that their overexpression would be associated with a better prognosis in cancer. However, kisspeptin/GPR54 interactions (autocrine, paracrine, and/or endocrine could also impact tumour behaviour in a negative manner. Here, for the first time, we associate the immunoreactivity of the kisspeptin/GPR54 ligand-receptor pair with favourable prognosis in a large cohort of ovarian carcinomas. Methods Immunohistochemical analysis for kisspeptin and GPR54 was performed on a tissue microarray (TMA consisting of 518 early stage ovarian carcinomas, all with linked clinical outcome data. The TMA was scored using a staining intensity scale of 0 (negative, +1 (mild-moderate, and +2 (strong. Strong staining cases were considered either kisspeptin or GPR54 positive and designated as 1, while all other cases were considered negative and designated 0. All statistical analysis was conducted using two-sided tests and a p value equal to or less than 0.05 was considered significant. Results Kisspeptin and GPR54 immunoreactive cases show a favourable prognosis in univariable disease specific survival (p = 0.0023, p = 0.0092, as well as in overall survival (p = 0.0006, p = 0.0002. Furthermore, kisspeptin is an independent marker for favourable prognosis as determined by multivariable disease specific (p = 0.0046 and overall survival analysis (p = 0.0170, while GPR54 is an independent marker for overall survival only (p = 0.0303. Both kisspeptin positive and GPR54 positive cases are strongly associated with the ovarian carcinoma clear cell subtype (p Conclusion Kisspeptin and GPR54 immunoreactivity are significantly associated with favourable prognosis in both disease specific and overall survival, as well as being significantly associated with the clear

  4. From Policy to Compliance: Federal Energy Efficient Product Procurement

    Energy Technology Data Exchange (ETDEWEB)

    DeMates, Laurèn [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Scodel, Anna [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-09-06

    Federal buyers are required to purchase energy-efficient products in an effort to minimize energy use in the federal sector, save the federal government money, and spur market development of efficient products. The Federal Energy Management Program (FEMP)’s Energy Efficient Product Procurement (EEPP) Program helps federal agencies comply with the requirement to purchase energy-efficient products by providing technical assistance and guidance and setting efficiency requirements for certain product categories. Past studies have estimated the savings potential of purchasing energy-efficient products at over $500 million per year in energy costs across federal agencies.1 Despite the strong policy support for EEPP and resources available, energy-efficient product purchasing operates within complex decision-making processes and operational structures; implementation challenges exist that may hinder agencies’ ability to comply with purchasing requirements. The shift to purchasing green products, including energy-efficient products, relies on “buy in” from a variety of potential actors throughout different purchasing pathways. Challenges may be especially high for EEPP relative to other sustainable acquisition programs given that efficient products frequently have a higher first cost than non-efficient ones, which may be perceived as a conflict with fiscal responsibility, or more simply problematic for agency personnel trying to stretch limited budgets. Federal buyers may also face challenges in determining whether a given product is subject to EEPP requirements. Previous analysis on agency compliance with EEPP, conducted by the Alliance to Save Energy (ASE), shows that federal agencies are getting better at purchasing energy-efficient products. ASE conducted two reviews of relevant solicitations for product and service contracts listed on Federal Business Opportunities (FBO), the centralized website where federal agencies are required to post procurements greater

  5. Contemporary Social Work: an Analysis based on the federal budget

    National Research Council Canada - National Science Library

    Janaina Albuquerque de Camargo Schmidt; Mossicléía Mendes da Silva

    2015-01-01

      This study presents a critical reflection about Social Assistance policy, based on considerations about funds allocated to this policy in the federal budget highlighting the years of 2005, a landmark...

  6. Federal Prevailing Rate Advisory Committee (FPRAC) Annual Reports

    Data.gov (United States)

    Office of Personnel Management — Annual reports of the Federal Prevailing Rate Advisory Committee (FPRAC), which studies the prevailing (market) rate system for wages and other matters pertinent to...

  7. Fiscal federalism and equity in the state joint local governments ...

    African Journals Online (AJOL)

    Fiscal federalism and equity in the state joint local governments' account: Oyo state in focus. ... Open Access DOWNLOAD FULL TEXT ... Data for this study were collected through secondary sources and descriptive and inferential statistical ...

  8. Fiscal Federalism, Ethnic Minorities and the National Question in ...

    African Journals Online (AJOL)

    info

    Question in Nigeria: Revisiting the Case of the Niger Delta. People ... This study, using content analysis, examined the impact of fiscal federalism and the struggles of ethnic ... superior loyalty of the peoples over the Nigerian citizenship identity.

  9. Influence of job rotation on employee productivity in Federal ...

    African Journals Online (AJOL)

    Influence of job rotation on employee productivity in Federal University libraries ... productivity in library operation and also enhances increase in productivity in a ... The study therefore recommends that University librarians and management of ...

  10. From federated federalism to harmonized federalism: the case of EU subsidiarity scrutiny in Spain and Belgium

    NARCIS (Netherlands)

    Vandamme, T.

    2011-01-01

    In political science literature, federal systems can be classified as ‘dual’ or ‘cooperative’ polities. Also for legal research, this classification has proven to be a good tool for analysis as evidenced by the recent work of Robert Schütze when he described the evolution of the EU from a dual to a

  11. IUCN guidelines using for assessment of plants from the Red Book of Russian Federation at regional level: a case study for the Republic of Mordovia (Russia

    Directory of Open Access Journals (Sweden)

    Khapugin Anatoliy A.

    2017-06-01

    Full Text Available There are 15 plant species included in the Russian Red Book, which occur in the Republic of Mordovia: Najas tenuissima, Koeleria sclerophylla, Stipa dasyphylla, S. pennata, S. pulcherrima, S. zalesskii, Fritillaria ruthenica, Iris aphylla, Cypripedium calceolus, Cephalanthera rubra, Epipogium aphyllum, Neottianthe cucullata, Orchis militaris, Neotinea ustulata, Thymus cimicinus. Of these, only C. calceolus is included in the Global Red List as Critically Endangered. Threat status for studied species in Mordovia was assessed, and their distribution dynamics in this region throughout 12 years was described. Recent floristic studies, inspections of herbariums and literature were used for searches all provided data. Grid mapping and IUCN criteria were used. Nine taxa were determined as Critically Endangered, three as Endangered, one as Vulnerable, one as Near Threatened and one as Data Deficient. The areas of occupancy and extent of occurrence in Mordovia were assessed for each taxon. All studied species should be included in the next edition of the Mordovian Red Book. F. ruthenica, E. aphyllum, N. ustulata, T. cimicinus require additional studies to confirm earlier observations.

  12. Strengthening the "Work" in Federal Work-Study: Improving Access to Financial Aid and Career-Related Work Experience for Low-Income and Post-Traditional Students

    Science.gov (United States)

    Kenefick, Elizabeth

    2015-01-01

    Low-income students must increasingly rely on work and loans to meet the high costs of college. Too often, though, the jobs they take are not in their field of study, which can impair the potential for career exploration and improved employment outcomes in the future. Despite the need to combine work and school in a meaningful way, only a limited…

  13. 77 FR 74825 - Information Collection: Federal and Non-Federal Financial Assistant Instruments

    Science.gov (United States)

    2012-12-18

    ... Forest Service Information Collection: Federal and Non-Federal Financial Assistant Instruments AGENCY...-Federal Financial Assistant Instruments. DATES: Comments must be received in writing on or before February... holidays. SUPPLEMENTARY INFORMATION: Title: Federal and Non-Federal Financial Assistant Instruments. OMB...

  14. 77 FR 34095 - Federated Investment Management Company and Federated ETF Trust; Notice of Application

    Science.gov (United States)

    2012-06-08

    ... COMMISSION Federated Investment Management Company and Federated ETF Trust; Notice of Application June 1...: Federated Investment Management Company (``Federated'') and Federated ETF Trust (the ``Trust''). Summary of... complete application may be obtained via the Commission's Web site by searching for the file number, or...

  15. Strategies Formulation of Cycling Federation in Iran

    Directory of Open Access Journals (Sweden)

    Arefeh Jamshidi

    2012-05-01

    Full Text Available The purpose of this research is to design and develop strategies of cycling federation in Iran. Here, the descriptive methodology would be applied based upon the case study. The Statistical population included the managers of cycling committees and boards, educated coaches and M.A students involved in cycling federation affairs. The statistical sample encompasses 50 individuals selected totally due to limited Statistical population. To collect the data, we used library resources, literature and background review, interviews and open as well as closed questionnaires. Having developed the closed questionnaire, we had the validity confirmed by the professors and their reliability was confirmed using Cronbach alpha Coefficient (a=0.94. For research findings analysis purpose, Friedman test and group discussion were taken into account. After identifying the most important strengths, weaknesses, opportunities and threats in the field of championship sport and ranking them in the existing order, we selected most important ones through group discussion. Different climates in country was the most important opportunity and lack of Television coverage was the most conspicuous threat. Finally, it was concluded cycling federation position in SWOT model was that of conservative.

  16. Evidence from the UK Zoonoses Action Plan in favour of localised anomalies of Salmonella infection on United Kingdom pig farms.

    Science.gov (United States)

    Clough, Helen E; Fenton, Sarah E; French, Nigel P; Miller, Alexander J; Cook, Alasdair J C

    2009-05-01

    Salmonella spp. are important food-borne pathogens. Abattoir studies demonstrated that almost a quarter of British finisher pigs might carry Salmonella, which led to the introduction by the British Pig Executive of their Zoonoses Action Plan (ZAP) to monitor the Salmonella status of United Kingdom pig farms by testing meat juice samples using an ELISA system. We used the K-function and approaches from the field of geostatistics to study routine data from ZAP. We demonstrated that there is statistical evidence that geographically localized anomalies of Salmonella infection were present in one of three regions studied. The physical mechanisms underlying this structure remain unclear: spatial structure might be present as a result of shared spatially structured (second-order) or non-spatially structured (first-order) risk factors, transmission processes, or a combination of both. We have demonstrated a way to use routinely collected surveillance data to enhance the knowledge of spatial disease epidemiology.

  17. Advocacy and coverage of needle exchange programs: results of a comparative study of harm reduction programs in Brazil, Bangladesh, Belarus, Ukraine, Russian Federation, and China

    OpenAIRE

    Burrows, Dave

    2006-01-01

    To prevent or mitigate an AIDS epidemic among injecting drug users (IDUs), effective activities need to be implemented on a large enough scale to reach and assist sufficient numbers of drug users and thereby change their risk behaviors related to drug use and sex. Recent work by UNAIDS on "high coverage sites", adopting the above strategies, has shown that one of the key elements in achieving high coverage is ongoing and sophisticated advocacy. High coverage harm reduction sites were studied ...

  18. Provision of educational service with the use of distance technologies for disabled persons (case study: the state of Alaska and Nothern regions of the Russian Federation)

    OpenAIRE

    V. A. Lipatov

    2016-01-01

    The distance education contributes to the solution of educational problems of disabled persons. The study of foreign experience is extremely important. North American universities saved up a wide experience in this sphere. Unlike self-made software products created by many Russian universities, Blackboard is the leading educational software package that professionally helps to solve educational problems of disabled persons. The international University of the Arctic has a growing interest in ...

  19. Implicit self-esteem and social anxiety : differential self-favouring effects in high and low anxious individuals

    NARCIS (Netherlands)

    de Jong, Peter

    2002-01-01

    This study was designed to investigate the role of negative self-image in social phobia. Participants were 19 high and 19 low socially anxious women. Because self-report measures of self-esteem are sensitive to self-presentation and impression management strategies, an implicit association test (IAT

  20. Nigeria: a federation gone wrong

    Directory of Open Access Journals (Sweden)

    J.F. Kirsten

    1996-03-01

    Full Text Available Due to its size, large population, oil-based economy and geographical location in West Africa. Nigeria is regarded as an important state in Africa. The country is also one of the longest surviving federal states on the continent and therefore represents an ongoing experiment in federalism in the Third World. Since its independence in 1960, however, Nigeria has been devastated by chronic political instability. This article tries to address the issue why this is the case and to identify ethnic-religious diversity and successive military regimes as the most important sources for the mentioned political unrest. The course and nature of political instability in Nigeria is pul in historical context - a context which also include the secession attempt by Riafra as one of the tragic highlights in the past of Nigeria. In conclusion, the author speculates on ways and options as to how secession attempts can be prevented and a larger amount of national political stability be achieved.

  1. Awareness, knowledge and practices of breast cancer screening measures among female postgraduate students of a Nigerian Federal University: a cross-sectional study.

    Science.gov (United States)

    Aluko, Joel Ojo; Ojelade, Mary Funmilayo; Sowunmi, C Olanrewaju; Oluwatosin, O Abimbola

    2014-09-01

    Annually, over a million new cases of breast cancer results in about 375,000 deaths worldwide. Recently, the burden of the disease has been on the increase in Nigeria and most cases present in hospitals late when cure becomes elusive. The choice of postgraduate students for this study was as a result of their potential to impact positively on the rest of the population by the virtue of their present or future positions. This forms the basis for this study. This cross-sectional descriptive study recruited 278 female postgraduate students of the University of Ibadan, Nigeria as participants using purposive sampling technique. Data were collected with the aid of a validated structured questionnaire. The research protocol was approved by the UI/UCH Ethical Committee. Both descriptive and inferential statistics were used for data analysis with the aid of Statistical Package of Social Sciences (SPSS) version 16. The students' mean age was 27 years ± 5.1 Std. Most of the postgraduate students were aware of the breast self examination (BSE), clinical breast examination (CBE) and mammography through health workers. Out of 159 respondents that claimed to be practicing BSE, 118 (58.4%) used to practice it occasionally. Out of 53 postgraduate students that had CBE done, 7.4% had CBE done by nurse/midwives. Among the students 11.4% had good knowledge of BSE. Similarly, 33.7% had good knowledge of breast cancer risk factors. Besides, the higher the level of knowledge of breast cancer the more the possibility that postgraduate students will practice BSE (Chi-square = 15.169, df = 4, P-value = 0.004). It is suggested that health workers should reach students within the academic communities with effective breast cancer prevention campaign programmes. Besides, both printed and electronic media should be used for dissemination of health education/information to ensure wider coverage.

  2. EDGE study in Russian Federation: efficacy and safety of vildagliptine in comparison with other oral antidiabetic agents in patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    G R Galstyan

    2013-06-01

    Full Text Available According to international consensus, metformin is acknowledged as a first-line therapeutic agent for type 2 diabetes mellitus (T2DM. However, in most cases this treatment eventually requires intensification by supplementation with other hypoglycemic medications. The aim of the EDGE study (Effective Diabetes control with vildaGliptin and vildagliptin/mEtformin was to assess the efficacy and safety of vildagliptin in comparison with other oral agents in routine management of patients with T2DM that has been poorly controlled by metformin monotherapy.

  3. The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release

    OpenAIRE

    Escudero, Claudia A; Lazo, Oscal M.; Galleguillos, Carolina; Parraguez, Jose I.; Lopez-Verrilli, Maria A.; Cabeza, Carolina; Leon, Luisa; Saeed, Uzma; Retamal, Claudio; Gonzalez, Alfonso; Marzolo, Maria-Paz; Bruce D Carter; Court, Felipe A.; Bronfman, Francisca C.

    2014-01-01

    The p75 neurotrophin receptor (p75, also known as NGFR) is a multifaceted signalling receptor that regulates neuronal physiology, including neurite outgrowth, and survival and death decisions. A key cellular aspect regulating neurotrophin signalling is the intracellular trafficking of their receptors; however, the post-endocytic trafficking of p75 is poorly defined. We used sympathetic neurons and rat PC12 cells to study the mechanism of internalisation and post-endocytic trafficking of p75. ...

  4. Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT promoter methylation as independent favourable prognostic factor

    Directory of Open Access Journals (Sweden)

    Smrdel Uros

    2016-12-01

    Full Text Available In spite of significant improvement after multi-modality treatment, prognosis of most patients with glioblastoma remains poor. Standard clinical prognostic factors (age, gender, extent of surgery and performance status do not clearly predict long-term survival. The aim of this case-control study was to evaluate immuno-histochemical and genetic characteristics of the tumour as additional prognostic factors in glioblastoma.

  5. User facilities at federal laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Baron, S.; Marcuse, W.

    1988-04-01

    Recent initiatives by the Congress and the Administration have been directed to improving American industrial competitiveness. One of these initiatives is directed to encouraging industrial users to avail themselves of special facilities existent at federal laboratories. The facilities available at the National Bureau of Standards (NBS) and seven Department of Energy (DOE) laboratories are presented here. One facility at each Laboratory is described in detail, the remainder are listed with the names and telephone numbers of individuals to contact for further information.

  6. Melanoma patients with unknown primary site or nodal recurrence after initial diagnosis have a favourable survival compared to those with synchronous lymph node metastasis and primary tumour.

    Directory of Open Access Journals (Sweden)

    Benjamin Weide

    Full Text Available BACKGROUND: A direct comparison of prognosis between patients with regional lymph node metastases (LNM detected synchronously with the primary melanoma (primary LNM, patients who developed their first LNM subsequently (secondary LNM and those with initial LNM in melanoma with unknown primary site (MUP is missing thus far. PATIENTS AND METHODS: Survival of 498 patients was calculated from the time point of the first macroscopic LNM using Kaplan Meier and multivariate Cox hazard regression analysis. RESULTS: Patients with secondary LNM (HR = 0.67; p = 0.009 and those with initial LNM in MUP (HR = 0.45; p = 0.008 had a better prognosis compared to patients with primary LNM (median survival time 52 and 65 vs. 24 months, respectively. A high number of involved nodes, the presence of in-transit/satellite metastases and male gender had an additional independent unfavourable effect. CONCLUSIONS: Survival of patients with LNM in MUP and with secondary LNM is similar and considerably more favourable compared to those with primary LNM. This difference needs to be considered during patient counselling and for stratification purposes in clinical trials. The assumption of an immune privilege of patients with MUP which is responsible for rejection of the primary melanoma, and results in a favourable prognosis is not supported by our data.

  7. Syndromic surveillance: etiologic study of acute febrile illness in dengue suspicious cases with negative serology. Brazil, Federal District, 2008 Vigilância sindrômica: estudo etiológico de doenças febris agudas a partir dos casos suspeitos de dengue com sorologia não reagente. Distrito Federal, Brasil, 2008

    Directory of Open Access Journals (Sweden)

    Ailton Domicio da Silva

    2010-10-01

    Full Text Available With the aim of identifying the etiology of acute febrile illness in patients suspected of having dengue, yet with non reagent serum, a descriptive study was conducted with 144 people using secondary serum samples collected during convalescence. The study was conducted between January and May of 2008. All the exams were re-tested for dengue, which was confirmed in 11.8% (n = 17; the samples that remained negative for dengue (n = 127 were tested for rubella, with 3.9% (n = 5 positive results. Among those non reactive for rubella (n = 122, tests were made for leptospirosis and hantavirus. Positive tests for leptospirosis were 13.9% (n = 17 and none for hantavirus. Non reactive results (70.8% were considered as Indefinite Febrile Illness (IFI. Low schooling was statistically associated with dengue, rubella and leptospirosis (p = 0.009, dyspnea was statistically associated with dengue and leptospirosis (p = 0.012, and exanthem/petechia with dengue and rubella (p = 0.001. Among those with leptospirosis, activities in empty or vacant lots showed statistical association with the disease (p = 0.013. Syndromic surveillance was shown to be an important tool in the etiologic identification of IFI in the Federal District of Brazil.Com o objetivo de identificar a etiologia de doenças febris agudas, em suspeitos de dengue com sorologia não reagente, realizou-se estudo descritivo com 144 pessoas utilizando amostras de soro coletados na convalescença, entre janeiro e março de 2008. Todos os exames foram re-testados para dengue, sendo as amostras negativas, processadas para rubéola (n = 127. Dentre as não reagentes para rubéola, submeteu-se ao teste para leptospirose (n = 122, e em se permanecendo sem diagnóstico, testou-se para hantavirose. Confirmou-se dengue em 11,8% (n = 17, rubéola em 3,9% (n = 5 e leptospirose em 13,9% (n = 17. Os resultados não reagentes foram considerados como doença febril aguda indiferenciada (DFI em 70.8% dos casos

  8. Findability of Federal Research Data

    Science.gov (United States)

    Hourcle, J. A.

    2013-12-01

    Findability of Federal Research Data Although many of the federal agencies have been providing access to scientific research data for years if not decades, the findability of the data has been quite lacking. Many discipline-wide efforts have been made in the big science communities, such as PDS for planetary science and the VOs in night time astronomy and heliophysics, but there is a lack of single entry point for someone looking for data. The science.gov website contains links to many of these big-science search systems, but doesn't differentiate between links to science quality data and websites or browse products, making it more difficult to search specifically for data. The data.gov website is a useful repository for PIs of small science data to stash their data, particularly as it allows for interested parties to interact with tabular data. Unfortunately, as each group thinks of their data differently, much of what's now in the system is a mess; collections of data being tracked as individual records with no relationships between them. Big science projects also get tracked as single records, potentially with only a single record for missions with multiple instruments and significantly different data series. We present recommendations on how to improve the findability of federal research data on data.gov, based on years of working on the Virtual Solar Observatory and withing the science informatics community.

  9. Improving federal response to drought

    Energy Technology Data Exchange (ETDEWEB)

    Wilhite, D.A.; Rosenberg, N.J.; Glantz, M.H.

    1986-03-01

    Severe and widespread drought occurred over a large portion of the US between 1974 and 1977. Impacts on agriculture and other industries, as well as local water supplies, were substantial. The federal government responded with forty assistance programs administered by sixteen federal agencies. Assistance was provided primarily in the form of loans and grants to people, businesses and governments experiencing hardship caused by drought. The total cost of the program is estimated at $7-8 billion. Federal response to the mid-1970s drought was largely untimely, ineffective and poorly coordinated. Four recommendations are offered that, if implemented, would improve future drought assessment and response efforts: 1) reliable and timely informational products and dissemination plans; 2) improved impact assessment techniques, especially in the agricultural sector, for use by government to identify periods of enhanced risk and to trigger assistance measures; 3) administratively centralized drought declaration procedures that are well publicized and consistently applied; and 4) standby assistance measures that encourage appropriate levels of risk management by producers and that are equitable, consistent and predictable. The development of a national drought plan that incorporates these four items is recommended. Atmospheric scientists have an important role to play in the collection and interpretation of near-real time weather data for use by government decision makers.

  10. Study of the effects of applying Federal Motor Vehicle Safety Standards 203 and 204 to light trucks and vans. Modification No. 3 (final)

    Energy Technology Data Exchange (ETDEWEB)

    McLean, R.F.

    1979-05-31

    From a careful inspection of trucks, their possible compliance or non-compliance with the requirements of FMVSS 203 and 204 was determined. Where non-compliance was indicated, design studies were made to bring the trucks into compilance. The added weight of the new designs was estimated. Using established cost estimating procedures, the incremental costs of the new design features were estimated. The manufacturing, wholesale, dealer markup, and total consumer costs were estimated. The average service life of the light trucks was used to establish a lifetime fuel cost based on the effects of the weight increases. The industry's leadtime requirements were discussed. Based on 1978 production volumes, the average cost per truck of complying with FMVSS 203 and 204 would be $11.35 per truck.

  11. PROPAFENONE FOR SINUS RHYTHM RECOVERY AND SUPPORT IN PATIENTS WITH PERSISTENT FORM OF AURICULAR FIBLILLATION. “PROMETHEUS” – OPENED MULTICENTER STUDY IN RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    I. G. Fomina

    2006-01-01

    Full Text Available Aim. To study efficiency and safety of propafenone internally used for recovery and support of sinus rhythm in patients with the persistent form of auricular fibrillation (AF. Material and methods. 503 patients with the persistent form of AF, aged 31-68 years were included into multicenter study. Patients were randomized into 2 groups. First group included 285 patients, who were prescribed propafenone (Propanorm, PRO.MED.CS Praha a.s., Czech Republic in a single per oral dose of 600 mg for AF paroxysm relief. Second group included 218 patients, who took propafenone for AF paroxysm prevention in daily dose of 450 mg. Efficiency of sustaining antiarrhythmic therapy was assessed in 1, 3 and 9 months after the treatment started by carrying out daily monitoring of EKG. Results. Propafenone in a single per oral dose of 600 mg leaded to sinus rhythm recovery in 230 (81% patients. Average time for sinus rhythm recovery made up 210±50 minutes. Relief, caused by propafenone within 4 hours after taking the drug, was observed in 182 (64% patients. Propafenone in dose of 450 mg daily lets keep sinus rhythm after 1 month of treatment in 161 patients (74%, after 3 months – in 130 patients (60% and after 9 months – in 98 patients (45%. Effect of preventive antiarythmic therapy within first 3 months of treatment with propafenone can be regarded good, and within 9 months – satisfactory. Conclusion. Propafenone in per oral single dose of 600 mg is an efficient method of sinus rhythm recovery in patients with the persistent form of AF, and its long-term usage in dose 450 mg daily is an efficient and safe method of sinus rhythm support.

  12. Predation success by a plant-ant indirectly favours the growth and fitness of its host myrmecophyte.

    Directory of Open Access Journals (Sweden)

    Alain Dejean

    Full Text Available Mutualisms, or interactions between species that lead to net fitness benefits for each species involved, are stable and ubiquitous in nature mostly due to "byproduct benefits" stemming from the intrinsic traits of one partner that generate an indirect and positive outcome for the other. Here we verify if myrmecotrophy (where plants obtain nutrients from the refuse of their associated ants can explain the stability of the tripartite association between the myrmecophyte Hirtella physophora, the ant Allomerus decemarticulatus and an Ascomycota fungus. The plant shelters and provides the ants with extrafloral nectar. The ants protect the plant from herbivores and integrate the fungus into the construction of a trap that they use to capture prey; they also provide the fungus and their host plant with nutrients. During a 9-month field study, we over-provisioned experimental ant colonies with insects, enhancing colony fitness (i.e., more winged females were produced. The rate of partial castration of the host plant, previously demonstrated, was not influenced by the experiment. Experimental plants showed higher δ(15N values (confirming myrmecotrophy, plus enhanced vegetative growth (e.g., more leaves produced increased the possibility of lodging ants in leaf pouches and fitness (i.e., more fruits produced and more flowers that matured into fruit. This study highlights the importance of myrmecotrophy on host plant fitness and the stability of ant-myrmecophyte mutualisms.

  13. 78 FR 67200 - Federal-State Unemployment Compensation Program: Certifications for 2013 Under the Federal...

    Science.gov (United States)

    2013-11-08

    ... Employment and Training Administration Federal-State Unemployment Compensation Program: Certifications for 2013 Under the Federal Unemployment Tax Act AGENCY: Employment and Training Administration. ACTION: Notice. SUMMARY: The Secretary of Labor signed the annual certifications under the Federal Unemployment...

  14. Advocacy and coverage of needle exchange programs: results of a comparative study of harm reduction programs in Brazil, Bangladesh, Belarus, Ukraine, Russian Federation, and China.

    Science.gov (United States)

    Burrows, Dave

    2006-04-01

    To prevent or mitigate an AIDS epidemic among injecting drug users (IDUs), effective activities need to be implemented on a large enough scale to reach and assist sufficient numbers of drug users and thereby change their risk behaviors related to drug use and sex. Recent work by UNAIDS on "high coverage sites", adopting the above strategies, has shown that one of the key elements in achieving high coverage is ongoing and sophisticated advocacy. High coverage harm reduction sites were studied through literature search and site visits, including key informant interviews, review of service statistics, and data analysis, in order to document the steps that led to scaling up, the way coverage was defined in these sites, and the lessons learned from their efforts. Syringe-exchange programs can achieve high coverage of IDUs. Monitoring to determine regular reach (those who are in regular contact with harm reduction services) should be added to uniform data collection carried out by harm reduction programs. Advocacy is crucial to achieving high coverage.

  15. COMPARATIVE ANALYSIS OF MORTALITY FROM EXTERNAL CAUSES IN ST. PETERSBURG, NORTHWEST FEDERAL DISTRICT AND RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    T. N. Vorontsova

    2016-01-01

    Full Text Available The purpose of this study was to evaluate the mortality rate of St. Petersburg population from external causes in 2010–2015 in comparison with similar indicators for the Northwest Federal District and the Russian Federation. Materials and methods. The authors used the following data for analysis: annual long-term monitoring of St. Petersburg trauma services status conducted by coordination and methodological center of trauma and orthopedics; government reporting on mortality; data of Federal State Statistics Service (Rosstat; data of St.Petersburg Statistics Service (Petrostat; data of St. Petersburg Medical Information Analysis Center (MIAС; studies on mortality issues as well as methods of descriptive statistics. Results. From 2003 to 2014 St. Petersburg population mortality rate demonstrated a steady decline as well as generally in Russia. 2015 featured a slight increase in absolute number of deaths per year (+1.2% in St.Petersburg, while the similar indicator across the Russian Federation was still declining (-5.9%. In 2015 mortality from external causes in St. Petersburg constituted 68 deaths per 100 thousand inhabitants, which is 1.6 times less than in the Northwest federal district (109.6 per 100 thousand inhabitants, and 1.7 times less than in the Russian Federation – 112 per 100 thousand population. In the overall mortality structure of St. Petersburg population the external causes have been consistently occupying third place within recent years. In 2015 the proportion of deaths from external causes in general mortality amounted to 5.7%. Conclusions. According to official statistics since 2000 in St. Petersburg the mortality rate from all the major external causes reduced gradually, as well as in the Northwest federal district and on the whole in Russia. Various national and regional programs that have been rolled out in Russia allowed to reduce by half the mortality of working age population from homicide and from suicide by

  16. “Changing in favour of the team”: the collective dimension in the work of beach volleyball athletes

    Directory of Open Access Journals (Sweden)

    Louise Borba

    2017-07-01

    Full Text Available Thinking on the collective dimension of sports as a division of functions among athletes within a team may limit and conceal all the existing debates and dramas in such work activity. Thus, the aim of the present study is to assess how autonomous beach volleyball athletes manage their professional lives in the search for partners to form a pair who fits for “playing together”, although the work organisation in the aforementioned modality is extremely competitive and requires high turnover of its members. Based on Ergology, Ergonomics and Clinic Activity, we assume that athletes are required to put their sportive competences in synergy to form a pair, or to set up a team. Besides, above all, we expected these athletes to be able to build cognitive references, as well as common values, which enable communication and cooperation within work development.

  17. [Endarterectomy more favourable than stenting in symptomatic significant carotid stenosis: higher risk of ischaemic stroke or death following stenting].

    Science.gov (United States)

    Meerwaldt, Robbert; Beuk, Roland J; Huisman, Ad B; Manschot, Sanne M; Zeebregts, Clark J; Geelkerken, Robert H

    2011-01-01

    Carotid endarterectomy (CEA) has proven its value in the treatment of patients with recent significant carotid artery stenosis. Percutaneous transluminal angioplasty with carotid artery stenting ('stenting' in short) is an alternative to CEA. The results of stenting and CEA in patients with symptomatic significant carotid artery stenosis were evaluated in 9 prospective randomized controlled trials and 11 meta-analyses. Almost all of these trials failed to show superiority of stenting to CEA. According to the 4 largest and most recent studies in this field the risk of a stroke or death within 30 days after the intervention is considerably higher following stenting than following CEA. In the long run the results of stenting and CEA seem to be comparable. CEA remains the gold standard in treatment of significant carotid artery stenosis, in particular in patients older than 70.

  18. Diffusion welding: a technology which is in favour; Soudage par diffusion. Une technologie qui a le vent en poupe

    Energy Technology Data Exchange (ETDEWEB)

    Macel, D. [Intitut de Soudure, 57 - Yutz (France)

    2009-01-15

    The aim of this work is to show the implication of the experimental parameters (welding temperature, temperature holding time, lining pressure, surface states, atmosphere) on the bonds quality. On the other hand, the feasibility of an homogeneous bond has been shown on two materials prepared by the Haynes firm: the HR-120 (iron-nickel-chromium alloy which has good properties at high temperature: 1100 C) and the HR-230 (other iron-nickel-chromium alloy which has a very good resistance at high temperature: until 1150 C and at oxidation too). The study of welding specimens by metallographic analysis allows to conclude to the establishment of healthy bonds, particularly if the experimental parameters are scrupulously respected. (O.M.)

  19. Coregistration of multimodal imaging is associated with favourable two-year seizure outcome after paediatric epilepsy surgery.

    Science.gov (United States)

    Perry, Michael Scott; Bailey, Laurie; Freedman, Daniel; Donahue, David; Malik, Saleem; Head, Hayden; Keator, Cynthia; Hernandez, Angel

    2017-03-01

    Multimodal coregistration uses multiple image datasets coregistered to an anatomical reference (i.e. MRI), allowing multiple studies to be viewed together. Commonly used in intractable epilepsy evaluation and generally accepted to improve localization of the epileptogenic zone, data showing that coregistration improves outcome is lacking. We compared seizure freedom following epilepsy surgery in paediatric patients, evaluated before and after the use of coregistration protocols at our centre, to determine whether this correlated with a change in outcome. We included paediatric epilepsy surgery patients with at least one anatomical and one functional neuroimaging study as part of their presurgical evaluation. Preoperatively designated palliative procedures and repeat surgeries were excluded. Multiple pre-, peri-, and postoperative variables were compared between groups with the primary outcome of seizure freedom. In total, 115 were included with an average age of 10.63 years (0.12-20.7). All evaluations included video-EEG (VEEG) and MRI. Seven (6%) had subtraction single-photon emission CT (SPECT), 46 (40%) had positron emission tomography (PET), and 62 (54%) had both as part of their evaluation. Sixty (52%) had extratemporal epilepsy and 25 (22%) were MRI-negative. Sixty-eight (59%) had coregistration. Coregistered patients were less likely to undergo invasive EEG monitoring (p=0.045) and were more likely to have seizure freedom at one (p=0.034) and two years (pseizure reduction compared to visual analysis of individual modalities. Imaging coregistration is associated with improved outcome, independent of other variables after surgery. Coregistered imaging may reduce the need for invasive EEG monitoring, likely due to improved confidence in presurgical localization. These findings support the use of multimodal coregistered imaging as part of the presurgical assessment in patients evaluated for surgical treatment of intractable epilepsy.

  20. Favourable ten-year overall survival in a Caucasian population with high probability of hereditary breast cancer

    Directory of Open Access Journals (Sweden)

    Pasini Giuseppe

    2010-03-01

    Full Text Available Abstract Background The purpose of our study was to compare differences in the prognosis of breast cancer (BC patients at high (H risk or intermediate slightly (IS increased risk based on family history and those without a family history of BC, and to evaluate whether ten-year overall survival can be considered a good indicator of BRCA1 gene mutation. Methods We classified 5923 breast cancer patients registered between 1988 and 2006 at the Department of Oncology and Haematology in Modena, Italy, into one of three different risk categories according to Modena criteria. One thousand eleven patients at H and IS increased risk were tested for BRCA1/2 mutations. The overall survival (OS and disease free survival (DFS were the study end-points. Results Eighty BRCA1 carriers were identified. A statistically significantly better prognosis was observed for patients belonging to the H risk category with respect to women in the IS and sporadic groups (82% vs.75% vs.73%, respectively; p BRCA1 carriers with BRCA-negative and sporadic BC (77% vs.77% vs.73%, respectively; p Conclusions Patients belonging to a population with a high probability of being BRCA1 carriers had a better prognosis than those with sporadic BC. Considering these results, women who previously had BC and had survived ten years could be selected for BRCA1 analysis among family members at high risk of hereditary BC during genetic counselling. Since only 30% of patients with a high probability of having hereditary BC have BRCA1 mutations, selecting women with a long term survival among this population could increase the rate of positive analyses, avoiding the use of expensive tests.

  1. Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer

    LENUS (Irish Health Repository)

    Ehlen, Asa

    2010-08-20

    Abstract Background We recently demonstrated that increased expression of the RNA-binding protein RBM3 is associated with a favourable prognosis in breast cancer. The aim of this study was to examine the prognostic value of RBM3 mRNA and protein expression in epithelial ovarian cancer (EOC) and the cisplatin response upon RBM3 depletion in a cisplatin-sensitive ovarian cancer cell line. Methods RBM3 mRNA expression was analysed in tumors from a cohort of 267 EOC cases (Cohort I) and RBM3 protein expression was analysed using immunohistochemistry (IHC) in an independent cohort of 154 prospectively collected EOC cases (Cohort II). Kaplan Meier analysis and Cox proportional hazards modelling were applied to assess the relationship between RBM3 and recurrence free survival (RFS) and overall survival (OS). Immunoblotting and IHC were used to examine the expression of RBM3 in a cisplatin-resistant ovarian cancer cell line A2780-Cp70 and its cisplatin-responsive parental cell line A2780. The impact of RBM3 on cisplatin response in EOC was assessed using siRNA-mediated silencing of RBM3 in A2780 cells followed by cell viability assay and cell cycle analysis. Results Increased RBM3 mRNA expression was associated with a prolonged RFS (HR = 0.64, 95% CI = 0.47-0.86, p = 0.003) and OS (HR = 0.64, 95% CI = 0.44-0.95, p = 0.024) in Cohort I. Multivariate analysis confirmed that RBM3 mRNA expression was an independent predictor of a prolonged RFS, (HR = 0.61, 95% CI = 0.44-0.84, p = 0.003) and OS (HR = 0.62, 95% CI = 0.41-0.95; p = 0.028) in Cohort I. In Cohort II, RBM3 protein expression was associated with a prolonged OS (HR = 0.53, 95% CI = 0.35-0.79, p = 0.002) confirmed by multivariate analysis (HR = 0.61, 95% CI = 0.40-0.92, p = 0.017). RBM3 mRNA and protein expression levels were significantly higher in the cisplatin sensitive A2780 cell line compared to the cisplatin resistant A2780-Cp70 derivative. siRNA-mediated silencing of RBM3 expression in the A2780 cells resulted

  2. 20th century global warming favoured enhanced intensity of extreme torrential events - a proglacial sediment record in NW French Alps

    Science.gov (United States)

    Wilhelm, B.; Arnaud, F.; Legaz, A.; Allignol, F.; Enters, D.; Revillon, S.

    2009-04-01

    During the past few yeas, considerable climate changes have been observed at high elevation areas of the European Alps. Additionally, one of the main results of high resolution climate modelling is a trend towards both dryer summer conditions and enhanced risk of extreme floods. This should have particularly dramatic consequences in alpine areas. Indeed, the development of tourism during the 20th century in the Alps and the rise of population density resulted in an increasing potential risk from natural hazards. Among them, torrential floods are some of the most common and widespread ones. They cause both loss of human life and high damage to property and infrastructure and are particularly destructive in mountain areas. For example, in August 2005, an unusual meteorological situation resulted in a series of catastrophic floods in most regions of the European Alps and particularly in the catchment of the Vorz river, downstream of proglacial Lac Blanc (2170 m a.s.l., Belledonne range, NW French Alps). We studied a series of sediment cores from Lac Blanc, spanning the last ca. 250 years. Through a coupled high resolution sedimentological and geochemical approach we documented about 100 flood deposits and measured their thickness. The age of each deposit has been assessed by radiochemical dating and the recognition of historically-known events - major earthquakes and historical atmospheric lead deposition. Furthermore, a detailed study of regional and local historical archives was conducted allowing us to relate the recognised flood deposits to the ones reported by local population. We hence obtained a flood calendar from 1740 to 2005 with the respective intensity of each event assessed by the thickness of the associated deposit. The flood frequency shows an important and punctual increase at the early end of the Little Ice Age (1830 - 1860) as a response to the beginning warming period, which was emphasized by the synchronous local glacier retreat. On the other hand

  3. The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release

    Science.gov (United States)

    Escudero, Claudia A.; Lazo, Oscal M.; Galleguillos, Carolina; Parraguez, Jose I.; Lopez-Verrilli, Maria A.; Cabeza, Carolina; Leon, Luisa; Saeed, Uzma; Retamal, Claudio; Gonzalez, Alfonso; Marzolo, Maria-Paz; Carter, Bruce D.; Court, Felipe A.; Bronfman, Francisca C.

    2014-01-01

    ABSTRACT The p75 neurotrophin receptor (p75, also known as NGFR) is a multifaceted signalling receptor that regulates neuronal physiology, including neurite outgrowth, and survival and death decisions. A key cellular aspect regulating neurotrophin signalling is the intracellular trafficking of their receptors; however, the post-endocytic trafficking of p75 is poorly defined. We used sympathetic neurons and rat PC12 cells to study the mechanism of internalisation and post-endocytic trafficking of p75. We found that p75 internalisation depended on the clathrin adaptor protein AP2 and on dynamin. More surprisingly, p75 evaded the lysosomal route at the level of the early endosome, instead accumulating in two different types of endosomes, Rab11-positive endosomes and multivesicular bodies (MVBs) positive for CD63, a marker of the exosomal pathway. Consistently, depolarisation by KCl induced the liberation of previously endocytosed full-length p75 into the extracellular medium in exosomes. Thus, p75 defines a subpopulation of MVBs that does not mature to lysosomes and is available for exosomal release by neuronal cells. PMID:24569882

  4. High intensity interval training favourably affects antioxidant and inflammation mRNA expression in early-stage chronic kidney disease.

    Science.gov (United States)

    Tucker, Patrick S; Briskey, David R; Scanlan, Aaron T; Coombes, Jeff S; Dalbo, Vincent J

    2015-12-01

    Increased levels of oxidative stress and inflammation have been linked to the progression of chronic kidney disease. To reduce oxidative stress and inflammation related to chronic kidney disease, chronic aerobic exercise is often recommended. Data suggests high intensity interval training may be more beneficial than traditional aerobic exercise. However, appraisals of differing modes of exercise, along with explanations of mechanisms responsible for observed effects, are lacking. This study assessed effects of eight weeks of high intensity interval training (85% VO2max), versus low intensity exercise (45-50% VO2max) and sedentary behaviour, in an animal model of early-stage chronic kidney disease. We examined kidney-specific mRNA expression of genes related to endogenous antioxidant enzyme activity (glutathione peroxidase 1; Gpx1, superoxide dismutase 1; Sod1, and catalase; Cat) and inflammation (kidney injury molecule 1; Kim1 and tumour necrosis factor receptor super family 1b; Tnfrsf1b), as well as plasma F2-isoprostanes, a marker of lipid peroxidation. Compared to sedentary behaviour, high intensity interval training resulted in increased mRNA expression of Sod1 (p=0.01) and Cat (pinflammation.

  5. Nebular phase observations of the type-Ib supernova iPTF13bvn favour a binary progenitor

    CERN Document Server

    Kuncarayakti, H; Bersten, M C; Folatelli, G; Morrell, N; Hsiao, E Y; González-Gaitán, S; Anderson, J P; Hamuy, M; de Jaeger, T; Gutiérrez, C P; Kawabata, K S

    2015-01-01

    Aims. We present and analyse late-time observations of the type-Ib supernova with possible pre-supernova progenitor detection, iPTF13bvn, taken at $\\sim$300 days after the explosion, and discuss these in the context of constraints on the supernova's progenitor. Previous studies have proposed two possible natures for the progenitor of the supernova, i.e. a massive Wolf-Rayet star or a lower-mass star in close binary system. Methods. Our observations show that the supernova has entered the nebular phase, with the spectrum dominated by Mg~I]$\\lambda\\lambda$4571, [O~I]$\\lambda\\lambda$6300, 6364, and [Ca~II]$\\lambda\\lambda$7291, 7324 emission lines. We measured the emission line fluxes to estimate the core oxygen mass and compare the [O~I]/[Ca~II] line ratio with other supernovae. Results. The core oxygen mass of the supernova progenitor was estimated to be $\\lesssim$0.7 M$_\\odot$, which implies initial progenitor mass not exceeding $\\sim$15 -- 17 M$_\\odot$. Since the derived mass is too small for a single star to...

  6. The use of fibre-reinforced polymers (FRP in bridges as a favourable solution for the environment

    Directory of Open Access Journals (Sweden)

    Żyjewski Artur

    2017-01-01

    Full Text Available The purpose of this article is to show the modern engineering, in which sustainability and taking care of ecology play a significant role. The authors are focused on FRP composite materials and their applications in civil engineering. Case studies showing renovation and design of new bridges with the use of FRP are presented and discussed to clarify benefits, which this solution provides. Main advantages of FRP materials in comparison with traditional ones, like concrete or steel are showed. The environmental impact of composites is described with respect to all life cycle of a product. Furthermore, some forms of waste management are covered. Last part of the paper refers to scientific description of the pedestrian bridge made of FRP, which was realized under the Fobridge research grant. The group of researchers headed by professor Chróścielewski from Gdansk University of Technology has developed a design solution of the pedestrian bridge manufactured in one production cycle. Moreover, the footbridge construction contains a significant share of a recyclable material commonly called PET. The article contains main characteristics of the structure and production process based on the resin infusion.

  7. Competition for nitrogen between European beech and sycamore maple shifts in favour of beech with decreasing light availability.

    Science.gov (United States)

    Simon, Judy; Li, Xiuyuan; Rennenberg, Heinz

    2014-01-01

    Plant species use different strategies for maximizing growth and fitness under changing environmental conditions. At the ecosystem level, seedlings in particular compete with other vegetation components for light and nitrogen (N), which often constitute growth-limiting resources. In this study, we investigated the effect of light availability on the competition for N between seedlings of European beech and sycamore maple and analysed the consequences of this competition for the composition of N metabolites in fine roots. Our results show different strategies in N acquisition between beech and sycamore maple. Both species responded to reduced light availability by adapting their morphological and physiological traits with a decrease in biomass and net assimilation rate and an increase in specific leaf area and leaf area ratio. For beech seedlings, competition with sycamore maple led to a reduction in organic N uptake capacity. Reduced light availability led to a decrease in ammonium, but an increase in glutamine-N uptake capacity in sycamore maple. However, this response was stronger compared with that of beech and was accompanied by reduced growth. Thus, our results suggest better adaptation of N acquisition to reduced light availability in beech compared with sycamore maple seedlings.

  8. Favourable outcome of posterior decompression and stabilization in lordosis for cervical spondylotic myelopathy: the spinal cord "back shift" concept.

    Science.gov (United States)

    Denaro, Vincenzo; Longo, Umile Giuseppe; Berton, Alessandra; Salvatore, Giuseppe; Denaro, Luca

    2015-11-01

    Surgical management of patients with multilevel CSM aims to decompress the spinal cord and restore the normal sagittal alignment. The literature lacks of high level evidences about the best surgical approach. Posterior decompression and stabilization in lordosis allows spinal cord back shift, leading to indirect decompression of the anterior spinal cord. The purpose of this study was to investigate the efficacy of posterior decompression and stabilization in lordosis for multilevel CSM. 36 out of 40 patients were clinically assessed at a mean follow-up of 5, 7 years. Outcome measures included EMS, mJOA Score, NDI and SF-12. Patients were asked whether surgery met their expectations and if they would undergo the same surgery again. Bone graft fusion, instrumental failure and cervical curvature were evaluated. Spinal cord back shift was measured and correlation with EMS and mJOA score recovery rate was analyzed. All scores showed a significative improvement (p 0.05). Ninety percent of patients would undergo the same surgery again. There was no deterioration of the cervical alignment, posterior grafted bones had completely fused and there were no instrument failures. The mean spinal cord back shift was 3.9 mm (range 2.5-4.5 mm). EMS and mJOA recovery rates were significantly correlated with the postoperative posterior cord migration (P lordosis is a valuable procedure for patients affected by multilevel CSM, leading to significant clinical improvement thanks to the spinal cord back shift. Postoperative lordotic alignment of the cervical spine is a key factor for successful treatment.

  9. Towards reducing DBP formation potential of drinking water by favouring direct ozone over hydroxyl radical reactions during ozonation.

    Science.gov (United States)

    De Vera, Glen Andrew; Stalter, Daniel; Gernjak, Wolfgang; Weinberg, Howard S; Keller, Jurg; Farré, Maria José

    2015-12-15

    When ozonation is employed in advanced water treatment plants to produce drinking water, dissolved organic matter reacts with ozone (O3) and/or hydroxyl radicals (OH) affecting disinfection byproduct (DBP) formation with subsequently used chlorine-based disinfectants. This study presents the effects of varying exposures of O3 and •OH on DBP concentrations and their associated toxicity generated after subsequent chlorination. DBP formation potential tests and in vitro bioassays were conducted after batch ozonation experiments of coagulated surface water with and without addition of tertiary butanol (t-BuOH, 10 mM) and hydrogen peroxide (H2O2, 1 mg/mg O3), and at different pH (6-8) and transferred ozone doses (0-1 mg/mg TOC). Although ozonation led to a 24-37% decrease in formation of total trihalomethanes, haloacetic acids, haloacetonitriles, and trihaloacetamides, an increase in formation of total trihalonitromethanes, chloral hydrate, and haloketones was observed. This effect however was less pronounced for samples ozonated at conditions favoring molecular ozone (e.g., pH 6 and in the presence of t-BuOH) over •OH reactions (e.g., pH 8 and in the presence of H2O2). Compared to ozonation only, addition of H2O2 consistently enhanced formation of all DBP groups (20-61%) except trihalonitromethanes. This proves that •OH-transformed organic matter is more susceptible to halogen incorporation. Analogously, adsorbable organic halogen (AOX) concentrations increased under conditions that favor •OH reactions. The ratio of unknown to known AOX, however, was greater at conditions that promote direct O3 reactions. Although significant correlation was found between AOX and genotoxicity with the p53 bioassay, toxicity tests using 4 in vitro bioassays showed relatively low absolute differences between various ozonation conditions.

  10. Favourable outcomes of {sup 177}Lu-octreotate peptide receptor chemoradionuclide therapy in patients with FDG-avid neuroendocrine tumours

    Energy Technology Data Exchange (ETDEWEB)

    Kashyap, Raghava [Peter MacCallum Cancer Center, Centre for Cancer Imaging, Melbourne (Australia); Hofman, Michael S.; Kong, Grace; Akhurst, Timothy; Eu, Peter [Peter MacCallum Cancer Center, Centre for Cancer Imaging, Melbourne (Australia); Peter MacCallum Cancer Centre, Neuroendocrine Tumour Service, Melbourne (Australia); Michael, Michael [University of Medicine, Department of Medicine, Melbourne (Australia); Peter MacCallum Cancer Centre, Division of Cancer Medicine, Melbourne (Australia); University of Melbourne, The Sir Peter MacCallum Department of Oncology, Melbourne (Australia); Zannino, Diana [Peter MacCallum Cancer Centre, Biostatistics and Clinical Trials, Melbourne (Australia); Hicks, Rodney J. [Peter MacCallum Cancer Center, Centre for Cancer Imaging, Melbourne (Australia); Peter MacCallum Cancer Centre, Neuroendocrine Tumour Service, Melbourne (Australia); University of Melbourne, The Sir Peter MacCallum Department of Oncology, Melbourne (Australia)

    2014-09-11

    Increased glycolytic activity on FDG PET/CT defines a subgroup of patients with metastatic gastroenteropancreatic neuroendocrine tumour (NET) with a poor prognosis. A limited range of systemic treatment options exist for more aggressive NET. The role of peptide receptor chemoradionuclide therapy (PRCRT) in such patients is, however, unclear. This retrospective study assessed the outcomes of patients with FDG-avid NET treated with PRCRT. Clinical, biochemical and imaging response was assessed after completion of induction treatment of PRCRT with 5-fluorouracil in 52 patients selected for treatment on the basis of somatostatin-receptor imaging without spatially discordant FDG-avid disease. Of the cohort, 67 % had received prior chemotherapy. Overall survival (OS) and progression-free survival (PFS) were also analysed. PRCRT was well tolerated with negligible grade 3/4 toxicities. After a median follow-up period of 36 months, the median OS was not achieved with a median PFS of 48 months. At 3 months after completion of PRCRT 2 % of patients showed a complete anatomical response, 28 % a partial response, 68 % stable disease, and only 2 % progression. On FDG PET/CT, 27 % achieved a complete metabolic response during the follow-up period. A biochemical response (>25 % fall in chromogranin-A levels) was seen in 45 %. PRCRT is an effective treatment in patients with FDG-avid NET, even in patients who have failed conventional therapies. Given apparently higher response rates than with alternative therapeutic options and low toxicity, further research is needed to establish whether PRCRT should be used as a first-line treatment modality in this patient population. (orig.)

  11. Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor

    Science.gov (United States)

    Smrdel, Uros; Zwitter, Matjaz; Bostjancic, Emanuela; Zupan, Andrej; Kovac, Viljem; Glavac, Damjan; Bokal, Drago; Jerebic, Janja

    2016-01-01

    Abstract Background In spite of significant improvement after multi-modality treatment, prognosis of most patients with glioblastoma remains poor. Standard clinical prognostic factors (age, gender, extent of surgery and performance status) do not clearly predict long-term survival. The aim of this case-control study was to evaluate immuno-histochemical and genetic characteristics of the tumour as additional prognostic factors in glioblastoma. Patients and methods Long-term survivor group were 40 patients with glioblastoma with survival longer than 30 months. Control group were 40 patients with shorter survival and matched to the long-term survivor group according to the clinical prognostic factors. All patients underwent multimodality treatment with surgery, postoperative conformal radiotherapy and temozolomide during and after radiotherapy. Biopsy samples were tested for the methylation of MGMT promoter (with methylation specific polymerase chain reaction), IDH1 (with immunohistochemistry), IDH2, CDKN2A and CDKN2B (with multiplex ligation-dependent probe amplification), and 1p and 19q mutations (with fluorescent in situ hybridization). Results Methylation of MGMT promoter was found in 95% and in 36% in the long-term survivor and control groups, respectively (p < 0.001). IDH1 R132H mutated patients had a non-significant lower risk of dying from glioblastoma (p = 0.437), in comparison to patients without this mutation. Other mutations were rare, with no significant difference between the two groups. Conclusions Molecular and genetic testing offers additional prognostic and predictive information for patients with glioblastoma. The most important finding of our analysis is that in the absence of MGMT promoter methylation, longterm survival is very rare. For patients without this mutation, alternative treatments should be explored. PMID:27904447

  12. CLUB-MARTINI: Selecting Favourable Interactions amongst Available Candidates, a Coarse-Grained Simulation Approach to Scoring Docking Decoys.

    Directory of Open Access Journals (Sweden)

    Qingzhen Hou

    Full Text Available Large-scale identification of native binding orientations is crucial for understanding the role of protein-protein interactions in their biological context. Measuring binding free energy is the method of choice to estimate binding strength and reveal the relevance of particular conformations in which proteins interact. In a recent study, we successfully applied coarse-grained molecular dynamics simulations to measure binding free energy for two protein complexes with similar accuracy to full-atomistic simulation, but 500-fold less time consuming. Here, we investigate the efficacy of this approach as a scoring method to identify stable binding conformations from thousands of docking decoys produced by protein docking programs. To test our method, we first applied it to calculate binding free energies of all protein conformations in a CAPRI (Critical Assessment of PRedicted Interactions benchmark dataset, which included over 19000 protein docking solutions for 15 benchmark targets. Based on the binding free energies, we ranked all docking solutions to select the near-native binding modes under the assumption that the native-solutions have lowest binding free energies. In our top 100 ranked structures, for the 'easy' targets that have many near-native conformations, we obtain a strong enrichment of acceptable or better quality structures; for the 'hard' targets without near-native decoys, our method is still able to retain structures which have native binding contacts. Moreover, in our top 10 selections, CLUB-MARTINI shows a comparable performance when compared with other state-of-the-art docking scoring functions. As a proof of concept, CLUB-MARTINI performs remarkably well for many targets and is able to pinpoint near-native binding modes in the top selections. To the best of our knowledge, this is the first time interaction free energy calculated from MD simulations have been used to rank docking solutions at a large scale.

  13. 76 FR 31393 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-52; Introduction

    Science.gov (United States)

    2011-05-31

    ... implement Executive Order 13514, Federal Leadership in Environmental, Energy, and Economic Performance, and... specified, all Federal Acquisition Regulation (FAR) ] and other directive material contained in FAC...

  14. Federal Blue-Collar Employees: A Workforce in Transistion.

    Science.gov (United States)

    1992-12-01

    should include example, a GAO study of the Mare Island explicit consideration of the needs of the blue-collar downsizing in 1990 noted that the layoff ...setting personnel policies. 14. SUBJECT TERMS 15 NUMBER OF PAGES Federal Government, blue-collar workforce, downsizing , performance managem pg...Federal BIW-Colar Emp£lo .: A Workforn in Transition v contents Downsizing in the Blue-Collar W orkforce

  15. Mandatory Class 1 Federal Areas Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This web service contains the following layers: Mandatory Class 1 Federal Area polygons and Mandatory Class 1 Federal Area labels in the United States. The polygon...

  16. 76 FR 16016 - Sunshine Federal Register Notice

    Science.gov (United States)

    2011-03-22

    .... ] Briefing on Small Modular Reactors (Public Meeting) (Contact: Stephanie Coffin, 301-415-6877) This meeting... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Sunshine Federal Register Notice AGENCY HOLDING THE MEETINGS: Nuclear Regulatory Commission,...

  17. 76 FR 14107 - Sunshine Federal Register Notice

    Science.gov (United States)

    2011-03-15

    .... Briefing on Small Modular Reactors (Public Meeting). (Contact: Stephanie Coffin, 301-415-6877). This... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Sunshine Federal Register Notice AGENCY HOLDING THE MEETINGS: Nuclear Regulatory Commission....

  18. Integrity Constraint Checking in Federated Databases

    NARCIS (Netherlands)

    Grefen, Paul; Widom, Jennifer

    1996-01-01

    A federated database is comprised of multiple interconnected databases that cooperate in an autonomous fashion. Global integrity constraints are very useful in federated databases, but the lack of global queries, global transaction mechanisms, and global concurrency control renders traditional const

  19. FEDERAL BALANCING IN NIGERIA: A PARADIGM FOR ...

    African Journals Online (AJOL)

    user

    In this paper, this North/South dichotomy .... process just like any other system of government. It remains a viable ..... This is the federal character theory which was formulated ... The issue of revenue allocation and economics of federalism.

  20. FINANCIAL MEGAREGULATION IN THE RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    Ochakovsky V. A.

    2014-01-01

    Full Text Available 2013 became year of changes for a financial system of the Russian Federation. On the basis of the Central bank of the Russian Federation there the financial mega-regulator began to work

  1. Federal Aircraft Cost and Utilization Data

    Data.gov (United States)

    General Services Administration — Federal aviation data is submitted quarterly to the Federal Aviation Interactive Reporting System (FARIS) IT application. This is a GSA system which is a secure,...

  2. Federal Procurement Data System - FAADS API

    Data.gov (United States)

    General Services Administration — The Federal Award Assistance Data System (FAADS) has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP and XML,...

  3. 75 FR 12809 - Federal Aviation Administration

    Science.gov (United States)

    2010-03-17

    ... Federal Aviation Administration Notice of Intent To Rule on Request To Release Airport Property at the Dallas/Fort Worth International Airport, DFW Airport, Texas AGENCY: Federal Aviation Administration (FAA... Aviation Administration, Southwest Region, Airports Division, Texas Airports Development Office,...

  4. 78 FR 13395 - Federal Aviation Administration

    Science.gov (United States)

    2013-02-27

    ... Federal Aviation Administration Notice of Availability of Draft Alaska National Interest Lands Conservation Act (ANILCA) Section 810 Subsistence Evaluation. AGENCY: Federal Aviation Administration (FAA... Aviation Administration, Airports Division, 222 West 7th Avenue, Box 14, Anchorage, AK 99513. 5....

  5. 78 FR 25337 - Federal Aviation Administration

    Science.gov (United States)

    2013-04-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection Activities: Requests for Comments; Clearance... Administration (FAA), DOT. ACTION: Notice and request for comments. SUMMARY: In accordance with the...

  6. Federal Procurement Data System - FPDS API

    Data.gov (United States)

    General Services Administration — The Federal Procurement Data System (FPDS) Next Generation has been re-engineered as a real-time federal enterprise information system. Web services based on SOAP...

  7. Fiscal Federalism in Russia: A Canadian Perspective

    OpenAIRE

    2001-01-01

    This paper considers some of the key instrumental components of intergovernmental fiscal relations that arise in the Russian Federation -- expenditures, revenues, transfers, borrowing, and institutional arrangements -- in comparison both to Canada’s lengthy experience with federalism and to a framework developed on the basis of previous work on fiscal federalism in a variety of transitional and developing countries. Unsurprisingly, from either of these perspectives fiscal federalism in Russia...

  8. Federal Republic of Germany, A Country Study.

    Science.gov (United States)

    1982-02-01

    Toronto: Holt, Rinehart and Winston, 1972. Hoffman, G.N. A Geography of Europe. New York: Roland, 1953. 402 ".’ U ’ . .low Bibliography Kirsch , Hans...and Theory," The American Journal of Comparative Law, XXIV, No. 4, Fall 1976, 718-36. Heymont, Irving . Analysis of the Army Reserve Systems of Is- rael

  9. 76 FR 66754 - Federal Bureau of Prisons

    Science.gov (United States)

    2011-10-27

    ... Federal Bureau of Prisons Notice of Availability of the Record of Decision for Proposed Contract Award to... AGENCY: U.S. Department of Justice, Federal Bureau of Prisons. ACTION: Notice of a Record of Decision. SUMMARY: The U.S. Department of Justice, Federal Bureau of Prisons (BOP) announces the availability of...

  10. 40 CFR 62.13 - Federal plans.

    Science.gov (United States)

    2010-07-01

    ... municipal solid waste landfills Federal plan are contained in subpart GGG of this part. These requirements... requirements. (c) The substantive requirements of the hospital/ medical/infectious waste incinerator Federal... requirements of the commercial and industrial solid waste incineration units Federal plan are contained...

  11. The Implications of Federal Education Policy.

    Science.gov (United States)

    Conrad, Clifton; Cosand, Joseph

    The significant role of the federal government in the support of higher education is noted in a survey of the development and changing patterns of federal support, and a critical review of the directions of current federal policy is offered. Implications are drawn about the effects of this policy on such national concerns as providing equal…

  12. 78 FR 25524 - Federal Aviation Administration

    Science.gov (United States)

    2013-05-01

    ... TRANSPORTATION Federal Aviation Administration Notice of Request To Release Airport Property AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Intent to Rule on Request to Release Airport Property..., Airports Compliance Specialist, Federal Aviation Administration, Airports Division, ACE- 610C, 901...

  13. 49 CFR 397.71 - Federal standards.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Federal standards. 397.71 Section 397.71... standards. (a) A State or Indian tribe shall comply with the Federal standards under paragraph (b) of this... or may not be transported. (b) The Federal standards are as follows: (1) Enhancement of public...

  14. Federal government expands compliance initiatives.

    Science.gov (United States)

    Dugan, J K

    1997-09-01

    In 1995, the Federal government initiated Operation Restore Trust to increase enforcement of fraud and abuse regulations in Medicare and Medicaid programs. With the success of the original initiative, the government is expanding the project to additional states and program areas. The initial scrutiny of home health agencies, nursing homes, hospice care, and durable medical equipment is being expanded to managed care plans and acute care hospitals with an eye toward DRG creep. To manage this increased enforcement activity, healthcare organizations should institute comprehensive corporate compliance programs. Such programs should provide a framework that delineates responsibilities and provides a systematic means to resolve issues in a timely manner.

  15. Federal Wind Energy Research Program

    Science.gov (United States)

    1991-10-01

    The Office of Program Analysis (OPA) undertook an assessment of 55 research projects sponsored by the Federal Wind Energy Research Program. This report summarizes the results of that review. In accordance with statue and policy guidance, the program's research has targeted the sciences of wind turbine dynamics and the development of advanced components and systems. Wind turbine research has focused on atmospheric fluid dynamics, aerodynamics, and structural dynamics. Rating factors including project scientific and technical merit, appropriateness and level of innovation of the technical approach, quality of the project team, productivity, and probable impact on the program's mission. Each project was also given an overall evaluation supported with written comments.

  16. Favourable effect of TNF-alpha inhibitor (infliximab) on Blau syndrome in monozygotic twins with a de novo CARD15 mutation

    DEFF Research Database (Denmark)

    Milman, Nils; Andersen, Claus B.; Hansen, Annette

    2006-01-01

    Blau syndrome is a hereditary granulomatous disease caused by mutations in the CARD15 gene that is diagnosed in children of young age with exanthema/erythema, arthritis/periarthritis and/or uveitis. We report two cases of Blau syndrome in Danish Caucasian monozygotic male twins, exhibiting...... a heterozygous de novo R334W mutation in codon 334 of CARD15. The patients were initially diagnosed as having sarcoidosis. In both twins, symptoms (exanthema, arthritis/periarthritis) started at 1 year of age, and were followed by uveitis at 7-10 years of age. There was no involvement of the lungs or other...... quality of life. At follow up at 20 years of age (after 2-5 years of infliximab treatment) the twins had an almost normal physical appearance and a normal psychomotoric development, indicating a favourable short-term prognosis of the disease. Blau syndrome has pathologic, clinical and therapeutic features...

  17. Projeto "a escola promovendo hábitos alimentares saudáveis": comparação de duas estratégias de educação nutricional no Distrito Federal, Brasil "Promotion of healthy eating habits by schools" study: comparison of two nutrition education strategies in the Federal District of Brazil

    Directory of Open Access Journals (Sweden)

    Renata Tiene de Carvalho Yokota

    2010-02-01

    Full Text Available OBJETIVO: Analisar e comparar o conhecimento sobre nutrição de professores e alunos do Projeto "a escola promovendo hábitos alimentares saudáveis", submetidos a duas estratégias de educação nutricional em escolas do Distrito Federal. MÉTODOS: O Projeto Escola utilizou duas estratégias de intervenção em educação nutricional: intervenção nutricional (A ações educativas realizadas na comunidade escolar pela equipe; e intervenção nutricional (B ações educativas desenvolvidas por professores que frequentaram oficinas de capacitação. O conhecimento das crianças foi avaliado por meio de um instrumento sobre pirâmide dos alimentos e um sobre higiene pessoal; sendo aplicado com os professores um questionário do tipo verdadeiro ou falso. RESULTADOS: Foram avaliadas 4 escolas com intervenção A (180 alunos e 19 professores e 4 com intervenção B (129 alunos e 16 professores. A média de acertos no instrumento de pirâmide dos alimentos foi de 3,2 e 2,9 (p=0,37, respectivamente pelas crianças que receberam as intervenções nutricionais A e B. Na atividade sobre higiene pessoal, para estes mesmos alunos, observaram-se percentuais de acerto de 61,1% e 73,6% (p=0,10. Os professores que receberam as intervenções nutricionais A e B obtiveram percentuais de acertos semelhantes nos questionários, em torno de 90,0% (p=0,06. CONCLUSÃO: Observou-se que os dois tipos de intervenção de educação nutricional foram igualmente úteis para promover o conhecimento de alunos e professores. Portanto, faz-se necessário incentivar a realização de processos de educação nutricional no ambiente escolar, de acordo com a diretriz da Política Nacional de Alimentação e Nutrição que diz respeito à promoção da saúde.OBJECTIVE: The objective of this study was to analyze and compare the nutrition knowledge of teachers and students who participated in the study "Promotion of healthy eating habits by schools" and were submitted to two

  18. Federal and European Union Policy Making

    DEFF Research Database (Denmark)

    Dosenrode, Søren

    By using the policy cycle approach, this paper compares the policy-process in a number of Anglo-Saxon type federations with the policy-process in continental-European style federations from within the European Union (EU) area.  The comparison would reveal: a) distinct different styles of policy...... making in European style federations in relation with the Anglo-Saxon ones. b) that the policy-process in the EU resembles that of the European style federations, and c) the Constitutional Treaty (CT) or a possible CT-light would strengthen the federal policy-making characteristics already present...

  19. 78 FR 45617 - Student Assistance General Provisions, Federal Perkins Loan Program, Federal Family Education...

    Science.gov (United States)

    2013-07-29

    ... July 29, 2013 Part II Department of Education 34 CFR Parts 668, 674, 682, et al. Student Assistance General Provisions, Federal Perkins Loan Program, Federal Family Education Loan Program, and William D... 1840-AD12 Student Assistance General Provisions, Federal Perkins Loan Program, Federal Family...

  20. 78 FR 65767 - Student Assistance General Provisions, Federal Perkins Loan Program, Federal Family Education...

    Science.gov (United States)

    2013-11-01

    ... November 1, 2013 Part II Department of Education 34 CFR Parts 668, 674, 682, and 685 Student Assistance General Provisions, Federal Perkins Loan Program, Federal Family Education Loan Program, and William D... Assistance General Provisions, Federal Perkins Loan (Perkins Loan) Program, Federal Family Education...

  1. 77 FR 181 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-55; Introduction

    Science.gov (United States)

    2012-01-03

    ... Space Administration 48 CFR Chapter 1 Federal Acquisition Regulation; Final Rules #0;#0;Federal Register... Acquisition Regulation; Federal Acquisition Circular 2005-55; Introduction AGENCIES: Department of Defense (Do... Acquisition Regulation (FAR) rules agreed to by DoD, GSA, and NASA in this Federal Acquisition Circular...

  2. 77 FR 58818 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Science.gov (United States)

    2012-09-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal Direct... notice will be considered public records. Title of Collection: William D. Ford Federal Direct...

  3. 75 FR 8278 - Participation by Federal Candidates and Officeholders at Non-Federal Fundraising Events

    Science.gov (United States)

    2010-02-24

    ... 11 CFR Part 300 Participation by Federal Candidates and Officeholders at Non- Federal Fundraising... participation by Federal candidates and officeholders in non-Federal fundraising events, with a public hearing... fundraising events. See 74 FR 64016 (December 7, 2009). The NPRM stated that the Commission would hold...

  4. 76 FR 70510 - Federal Employees' Group Life Insurance Program: New Federal Employees' Group Life Insurance...

    Science.gov (United States)

    2011-11-14

    ... MANAGEMENT Federal Employees' Group Life Insurance Program: New Federal Employees' Group Life Insurance... Management (OPM) is announcing changes in premiums for certain Federal ] Employees' Group Life Insurance... coincided with the implementation of the Federal Employees' Life Insurance Improvement Act, Public Law...

  5. Differential impact of local and federal smoke-free legislation in Mexico: a longitudinal study among adult smokers Impacto diferencial de la legislación federal y local de espacios libres de humo de tabaco en México: un estudio longitudinal entre fumadores adultos

    Directory of Open Access Journals (Sweden)

    James F Thrasher

    2010-01-01

    Full Text Available Objective. To assess the impact of Mexico City and federal smoke-free legislation on secondhand tobacco smoke (SHS exposure and support for smoke-free laws. Material and Methods. Pre- and post-law data were analyzed from a cohort of adult smokers who participated in the International Tobacco Control (ITC Policy Evaluation Suvey in four Mexican cities. For each indicator, we estimated prevalence, changes in prevalence, and between-city differences in rates of change. Results. Self-reported exposure to smoke-free media campaigns generally increased more dramatically in Mexico City. Support for prohibiting smoking in regulated venues increased overall, but at a greater rate in Mexico City than in other cities. In bars and restaurants/cafés, self-reported SHS exposure had significantly greater decreases in Mexico City than in other cities; however, workplace exposure decreased in Tijuana and Guadalajara, but not in Mexico City or Ciudad Juárez. Conclusions. Although federal smoke-free legislation was associated with important changes smoke-free policy impact, the comprehensive smoke-free law in Mexico City was generally accompanied by a greater rate of change.Objetivo. Evaluar el impacto de la legislación federal y del Distrito Federal (DF de espacios libres de humo de tabaco (ELHT sobre la exposición al humo de tabaco y el apoyo a las leyes. Material y métodos. Se analizaron datos antes y después de la ley en una cohorte de fumadores adultos de cuatro ciudades mexicanas donde se aplicó la Encuesta Internacional para Evaluar las Políticas Públicas para el Control del Tabaco (Encuesta ITC. Para cada indicador, se estimó la prevalencia, cambios en la prevalencia y diferencias entre ciudades en las tasas de cambio. Resultados. La exposición autorreportada a las campañas sobre los ELHT incrementaron dramáticamente en el DF. El apoyo para prohibir fumar en lugares regulados aumentó en general, pero aumentó más en el DF. La exposici

  6. [Bringing criteria for external assessment of the quality of biochemical studies within the framework of the Federal System for External Evaluation of the Quality of Clinical Laboratory Studies, in conformity with requirements of the Order No. 45 of the Ministry of Health of Russia, 2/7/2000].

    Science.gov (United States)

    Zaikin, E V; Malakhov, V N

    2000-07-01

    Criteria for external assessment of the quality of evaluation of 23 biochemical parameters of the blood, meeting the standards of accuracy determined by the Order No. 45 of Ministry of Health of Russia of February 7, 2000 for intralaboratory quality control have been estimated. According to the data of the Federal System for External Evaluation of the Quality of Clinical Laboratory Studies, the percentage of results of analyses of test sera meeting these criteria has been estimated. Introduction of new criteria for external assessment of the quality of biochemical tests into the practice of the Federal System will not notably modify the currently used criteria with regard to the majority of biochemical parameters, except introduction of more stringent criteria for albumin and magnesium and less stringent for creatine kinase.

  7. Fear of deportation is not associated with medical or dental care use among Mexican-origin farmworkers served by a federally-qualified health center--faith-based partnership: an exploratory study.

    Science.gov (United States)

    López-Cevallos, Daniel F; Lee, Junghee; Donlan, William

    2014-08-01

    Migrant and seasonal farmworkers face many health risks with limited access to health care and promotion services. This study explored whether fear of deportation (as a barrier), and church attendance (as an enabling factor), were associated with medical and dental care use among Mexican-origin farmworkers. Interviews were conducted with 179 farmworkers who attended mobile services provided by a local federally-qualified health center (FQHC) in partnership with area churches, during the 2007 agricultural season. The majority of respondents (87 %) were afraid of being deported, and many (74 %) attended church. Although about half of participants reported poor/fair physical (49 %) and dental (58 %) health, only 37 % of farmworkers used medical care and 20 % used dental care during the previous year. Fear of deportation was not associated with use of medical or dental care; while church attendance was associated with use of dental care. Findings suggest that despite high prevalence of fear of deportation, support by FQHCs and churches may enable farmworkers to access health care services.

  8. Compliance of blood sampling procedures with the CLSI H3-A6 guidelines: An observational study by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) working group for the preanalytical phase (WG-PRE).

    Science.gov (United States)

    Simundic, Ana-Maria; Church, Stephen; Cornes, Michael P; Grankvist, Kjell; Lippi, Giuseppe; Nybo, Mads; Nikolac, Nora; van Dongen-Lases, Edmee; Eker, Pinar; Kovalevskaya, Svjetlana; Kristensen, Gunn B B; Sprongl, Ludek; Sumarac, Zorica

    2015-08-01

    An observational study was conducted in 12 European countries by the European Federation of Clinical Chemistry and Laboratory Medicine Working Group for the Preanalytical Phase (EFLM WG-PRE) to assess the level of compliance with the CLSI H3-A6 guidelines. A structured checklist including 29 items was created to assess the compliance of European phlebotomy procedures with the CLSI H3-A6 guideline. A risk occurrence chart of individual phlebotomy steps was created from the observed error frequency and severity of harm of each guideline key issue. The severity of errors occurring during phlebotomy was graded using the risk occurrence chart. Twelve European countries participated with a median of 33 (18-36) audits per country, and a total of 336 audits. The median error rate for the total phlebotomy procedure was 26.9 % (10.6-43.8), indicating a low overall compliance with the recommended CLSI guideline. Patient identification and test tube labelling were identified as the key guideline issues with the highest combination of probability and potential risk of harm. Administrative staff did not adhere to patient identification procedures during phlebotomy, whereas physicians did not adhere to test tube labelling policy. The level of compliance of phlebotomy procedures with the CLSI H3-A6 guidelines in 12 European countries was found to be unacceptably low. The most critical steps in need of immediate attention in the investigated countries are patient identification and tube labelling.

  9. Principles of effective USA federal fire management plans

    Science.gov (United States)

    Meyer, Marc D.; Roberts, Susan L.; Wills, Robin; Brooks, Matthew L.; Winford, Eric M.

    2015-01-01

    Federal fire management plans are essential implementation guides for the management of wildland fire on federal lands. Recent changes in federal fire policy implementation guidance and fire science information suggest the need for substantial changes in federal fire management plans of the United States. Federal land management agencies are also undergoing land management planning efforts that will initiate revision of fire management plans across the country. Using the southern Sierra Nevada as a case study, we briefly describe the underlying framework of fire management plans, assess their consistency with guiding principles based on current science information and federal policy guidance, and provide recommendations for the development of future fire management plans. Based on our review, we recommend that future fire management plans be: (1) consistent and compatible, (2) collaborative, (3) clear and comprehensive, (4) spatially and temporally scalable, (5) informed by the best available science, and (6) flexible and adaptive. In addition, we identify and describe several strategic guides or “tools” that can enhance these core principles and benefit future fire management plans in the following areas: planning and prioritization, science integration, climate change adaptation, partnerships, monitoring, education and communication, and applied fire management. These principles and tools are essential to successfully realize fire management goals and objectives in a rapidly changing world.

  10. Atributos de hortaliças sob a ótica de consumidores: estudo de caso do pimentão no Distrito Federal Attributes of vegetables based on consumer's needs: a case study on bell peppers in Distrito Federal, Brazil

    Directory of Open Access Journals (Sweden)

    Silvia S Onoyama

    2010-03-01

    Full Text Available Melhoristas de Capsicum da Embrapa Hortaliças estão orientando parte de seus esforços sob a ótica dos consumidores intermediários e finais com objetivo de aumentar as chances de sucesso de longo prazo do desenvolvimento de novas cultivares. Nesse cenário, este trabalho ilustra uma pesquisa, iniciada em 2007, com consumidores de pimentão do Distrito Federal para conhecer as principais características que são levadas em consideração no ato da compra. O estudo foi dividido em duas partes: um piloto com 444 consumidores de um grande supermercado e um levantamento com 500 consumidores finais de pimentão in natura de cinco supermercados de Brasília. Utilizou-se a análise de dados categóricos por meio do procedimento CATMOD do SAS para verificar a ordenação de importância dos atributos, os contrastes das médias, bem como a influência do perfil do comprador na avaliação das características envolvidas na compra. Em complemento, usou-se a análise de correspondência para a representação gráfica das relações multidimensionais das distâncias do grau de importância dos atributos do pimentão. Os consumidores enfatizaram a textura e as características relacionadas ao aspecto visual durante a compra do pimentão. Em adição, foram detectadas diferenças de percepção de alguns atributos dentre os consumidores quando segmentados por gênero, idade, grau de escolaridade, estado civil e localização do supermercado. Destaca-se, ainda, a maior preocupação das características funcionais por pessoas mais idosas. Estudos dessa natureza são essenciais para melhor orientar os programas de melhoramento genético vegetal.Capsicum (chili and bell peppers breeders at Embrapa Vegetables are focusing project activities to satisfy the demands of both growers and final consumers in order to increase the chances of success in, long-term development of new cultivars. So, a prospection study on consumer demands and perception on bell peppers

  11. Hemoglobinopatias no Distrito Federal, Brasil

    Directory of Open Access Journals (Sweden)

    J. Tavares-Neto

    1986-03-01

    Full Text Available Em uma amostra de 3137 pessoas, residentes no Distrito Federal, foram detectadas as seguintes hemoglobinas: em 3009(95,92% HbAA; em 91 (2,90% HbAS; em 20(0,64% HbAC; em 8 (0,26% talassemia beta minor; em 5(0,16% HbAJ alfa; em 3 (0,09% HbAM e em 1 (0,03% talassemia major associada com HbAS. A HbAS têm as seguintes freqüências, quanto ao grupo racial: branco - 1,84%; mulato claro 2,55%; mulato médio-3,68%; mulato escuro - 6,80%; negro -10,43% e mestiço de índio -3,85%.

  12. Estudo da sobrevida de pacientes com câncer de mama atendidas no hospital da Universidade Federal de Santa Maria, Rio Grande do Sul, Brasil Survival study of breast cancer patients treated at the hospital of the Federal University in Santa Maria, Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Anaelena Bragança de Moraes

    2006-10-01

    Full Text Available O objetivo deste estudo retrospectivo de base hospitalar foi descrever as condições de saúde e estimar a sobrevida de 252 pacientes, com diagnóstico prévio de câncer de mama, tratadas e acompanhadas no Ambulatório de Mastologia do Hospital Universitário de Santa Maria, Rio Grande do Sul, Brasil, no período de 1980 a 2000. Para a análise estatística foram utilizados o estimador de Kaplan-Meier e o modelo de Cox. A idade média das pacientes foi 54 anos, sendo que 73,4% apresentaram diagnóstico histológico de carcinoma ductal invasor, 63,9% não apresentaram comprometimento dos linfonodos regionais e 57,6% encontravam-se no estadiamento clínico II. Ao final do estudo, 64,7% das mulheres estavam vivas e sem câncer de mama, e 5,1% morreram por outra causa. A sobrevida estimada em 5 anos, foi de 87,7%, sendo os fatores prognósticos associados: tamanho do tumor (RR = 12,03; > 5cm, comprometimento (RR = 3,08; N1 e número de linfonodos ressecados (RR = 4,66; Nenhum, receptor de estrógeno (RR = 0,34 e c-erbB-2 (RR = 2,51. Com base nos achados deste estudo, destaca-se a importância de ações intensivas de orientação para implementar o rastreamento do câncer de mama, levando a diagnósticos em estádios precoces dessa neoplasia.This retrospective hospital-based study aimed to describe health conditions and to estimate the survival of 252 patients diagnosed with breast cancer and treated at the Mastology Outpatient Clinic at the University Hospital of the Federal University in Santa Maria, Rio Grande do Sul, Brazil, from 1980 to 2000. Analysis followed the Kaplan-Meier and Cox model. Mean age was 54, and 73.4% of the patients had a histological diagnosis of invasive ductal carcinoma, 63.9% showed no lymph node involvement, and 57.6% were clinical stage II. At the end of the study, 64.7% were alive and free of breast cancer and 5.1% had died of other causes. Five-year survival was 87.7% for all women, and prognostic factors associated

  13. The Domino Effects of Federal Research Funding.

    Science.gov (United States)

    Lanahan, Lauren; Graddy-Reed, Alexandra; Feldman, Maryann P

    2016-01-01

    The extent to which federal investment in research crowds out or decreases incentives for investment from other funding sources remains an open question. Scholarship on research funding has focused on the relationship between federal and industry or, more comprehensively, non-federal funding without disentangling the other sources of research support that include nonprofit organizations and state and local governments. This paper extends our understanding of academic research support by considering the relationships between federal and non-federal funding sources provided by the National Science Foundation Higher Education Research and Development Survey. We examine whether federal research investment serves as a complement or substitute for state and local government, nonprofit, and industry research investment using the population of research-active academic science fields at U.S. doctoral granting institutions. We use a system of two equations that instruments with prior levels of both federal and non-federal funding sources and accounts for time-invariant academic institution-field effects through first differencing. We estimate that a 1% increase in federal research funding is associated with a 0.411% increase in nonprofit research funding, a 0.217% increase in state and local research funding, and a 0.468% increase in industry research funding, respectively. Results indicate that federal funding plays a fundamental role in inducing complementary investments from other funding sources, with impacts varying across academic division, research capacity, and institutional control.

  14. The Domino Effects of Federal Research Funding.

    Directory of Open Access Journals (Sweden)

    Lauren Lanahan

    Full Text Available The extent to which federal investment in research crowds out or decreases incentives for investment from other funding sources remains an open question. Scholarship on research funding has focused on the relationship between federal and industry or, more comprehensively, non-federal funding without disentangling the other sources of research support that include nonprofit organizations and state and local governments. This paper extends our understanding of academic research support by considering the relationships between federal and non-federal funding sources provided by the National Science Foundation Higher Education Research and Development Survey. We examine whether federal research investment serves as a complement or substitute for state and local government, nonprofit, and industry research investment using the population of research-active academic science fields at U.S. doctoral granting institutions. We use a system of two equations that instruments with prior levels of both federal and non-federal funding sources and accounts for time-invariant academic institution-field effects through first differencing. We estimate that a 1% increase in federal research funding is associated with a 0.411% increase in nonprofit research funding, a 0.217% increase in state and local research funding, and a 0.468% increase in industry research funding, respectively. Results indicate that federal funding plays a fundamental role in inducing complementary investments from other funding sources, with impacts varying across academic division, research capacity, and institutional control.

  15. Federal agency support for healthy homes.

    Science.gov (United States)

    Brown, Mary Jean; Ammon, Matthew; Grevatt, Peter

    2010-01-01

    Numerous studies have demonstrated that housing interventions such as addressing structural deficiencies or lack of safety devices improve health. These successes, coupled with reports by health care and housing professionals of other health and safety issues in homes that they were unable to address, have renewed interest in promoting health by addressing unhealthy housing conditions--but with a holistic approach. The Centers for Disease Control and Prevention, US Department of Housing and Urban Development, and US Environmental Protection Agency fund programs to improve indoor air and drinking water quality and prevent childhood lead poisoning. All of these programs offer valuable lessons for designing more integrated programs. The federal agencies and their grantees have demonstrated that interagency collaboration is essential for successful outcomes. However, the Department of Housing and Urban Development, the Environmental Protection Agency, and the Centers for Disease Control recognize that no individual agency has all of the necessary resources or expertise to formulate national programs and policies and implement a national healthy homes agenda. Thus, they have come together with the US Department of Health and Human Services, the Department of Energy, the US Department of Agriculture, the National Institute of Standards and Technology, the National Institute of Environmental Health Sciences, and the Office of the Surgeon General to form an interagency working group to ensure that vigorous, healthy homes policies are implemented at federal, national, and community levels.

  16. 77 FR 45592 - Notice of Submission for OMB Review; Federal Student Aid; Federal Perkins Loan Program Master...

    Science.gov (United States)

    2012-08-01

    ...; Federal Perkins Loan Program Master Promissory Note SUMMARY: The Federal Perkins Loan Master Promissory... records. Title of Collection: Federal Perkins Loan Program Master Promissory Note. OMB Control...

  17. Interoperability between Heterogeneous Federation Architectures: Illustration with SAML and WS-Federation

    CERN Document Server

    Ates, Mikaël; Lardon, Jérémy; Fayolle, Jacques; Sauviac, B; 10.1109/SITIS.2007.148

    2008-01-01

    Digital identity management intra and inter information systems, and, service oriented architectures, are the roots of identity federation. This kind of security architectures aims at enabling information system interoperability. Existing architectures, however, do not consider interoperability of heterogeneous federation architectures, which rely on different federation protocols.In this paper, we try to initiate an in-depth reflection on this issue, through the comparison of two main federation architecture specifications: SAML and WS-Federation. We firstly propose an overall outline of identity federation. We furthermore address the issue of interoperability for federation architectures using a different federation protocol. Afterwards, we compare SAML and WS-Federation. Eventually, we define the ways of convergence, and therefore, of interoperability.

  18. Effects of a recreational physical activity and healthy habits orientation program, using an illustrated diary, on the cardiovascular risk profile of overweight and obese schoolchildren: a pilot study in a public school in Brasilia, Federal District, Brazil

    Directory of Open Access Journals (Sweden)

    Militão AG

    2013-11-01

    Full Text Available Angeliete Garcez Militão,1,2 Margô Gomes de Oliveira Karnikowski,3 Fernanda Rodrigues da Silva,4 Elba Sancho Garcez Militão,3 Raiane Maiara dos Santos Pereira,5 Carmen Silvia Grubert Campbell,2,5 1Department of Physical Education, Federal University of Rondonia, Brazil; 2Post-Graduate Program in Physical Education, Catholic University of Brasilia, Brazil; 3University of Brasilia, Brazil; 4Laboratory of Physical Evaluation and Training, 5Laboratory of Physical Education and Health Studies, Catholic University of Brasilia, Brazil Introduction: Educative strategies need to be adopted to encourage the consumption of healthy foods and to promote physical activity in childhood and adolescence. The effects of recreational physical activity and a health-habit orientation program using an illustrated diary on the cardiovascular risk profile of overweight and obese children was investigated. Methods: The weight and height of 314 schoolchildren aged between 9 and 11 years old, in a public school in Brasilia, Federal District, Brazil, were recorded. According to the body mass index (BMI classification proposed by the World Health Organization, 84 were overweight or obese for their age and sex. Of these children, 34 (40% participated in the study. Students were divided into two groups matched for sex, age, BMI, percent body fat (%BF: the intervention group (IG, n = 17 and the control group (CG, n = 17. The IG underwent a program of 10 weeks of exercise with recreational activities and health-habit orientation using an illustrated diary of habits, while no such interventions were used with the CG during the study period. Before and after the intervention, the children's weight, height, BMI, %BF, waist circumference (WC, maximum oxygen intake (VO2max, total cholesterol (TC, high density lipoprotein (HDL, low density lipoprotein (LDL, triglycerides, glucose, eating habits, and physical activity level (PAL were assessed. In analyzing the data, we used

  19. 2010 Northwest Federal Market Assessment Report

    Energy Technology Data Exchange (ETDEWEB)

    Scanlon, Tim; Sandusky, William F.

    2011-09-01

    The primary intent of this market assessment is to provide insights on the effectiveness of current energy efficiency and renewable energy program offerings available to Federal sites in the region. The level of detail, quality and currency of the data used in this market assessment varies significantly by Federal agency and energy efficiency service provider. Limited access to some Federal sites, limited availability of key points of contact, time/resource constraints, and other considerations limited the total number of Federal agencies and energy efficiency service providers participating in the survey.

  20. Federal Technology Transfer Act Success Stories

    Science.gov (United States)

    Successful Federal Technology Transfer Act (FTTA) partnerships demonstrate the many advantages of technology transfer and collaboration. EPA and partner organizations create valuable and applicable technologies for the marketplace.

  1. Agglutinating mouse IgG3 compares favourably with IgMs in typing of the blood group B antigen: Functionality and stability studies.

    Science.gov (United States)

    Klaus, Tomasz; Bzowska, Monika; Kulesza, Małgorzata; Kabat, Agnieszka Martyna; Jemioła-Rzemińska, Małgorzata; Czaplicki, Dominik; Makuch, Krzysztof; Jucha, Jarosław; Karabasz, Alicja; Bereta, Joanna

    2016-08-03

    Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained agglutinating mouse IgG3 that recognized antigen B of the human ABO blood group system. Mouse IgG3 is an intriguing isotype that has the ability to form Fc-dependent oligomers. However, F(ab')2 fragments of the IgG3 were sufficient to agglutinate type B red blood cells; therefore, IgG3-triggered agglutination did not require oligomerization. Molecular modelling indicated that mouse IgG3 has a larger range of Fab arms than other mouse IgG subclasses and that the unique properties of mouse IgG3 are likely due to the structure of its hinge region. With a focus on applications in diagnostics, we compared the stability of IgG3 and two IgMs in formulated blood typing reagents using an accelerated storage approach and differential scanning calorimetry. IgG3 was much more stable than IgMs. Interestingly, the rapid decrease in IgM activity was caused by aggregation of the molecules and a previously unknown posttranslational proteolytic processing of the μ heavy chain. Our data point to mouse IgG3 as a potent diagnostic tool.

  2. Agglutinating mouse IgG3 compares favourably with IgMs in typing of the blood group B antigen: Functionality and stability studies

    Science.gov (United States)

    Klaus, Tomasz; Bzowska, Monika; Kulesza, Małgorzata; Kabat, Agnieszka Martyna; Jemioła-Rzemińska, Małgorzata; Czaplicki, Dominik; Makuch, Krzysztof; Jucha, Jarosław; Karabasz, Alicja; Bereta, Joanna

    2016-01-01

    Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained agglutinating mouse IgG3 that recognized antigen B of the human ABO blood group system. Mouse IgG3 is an intriguing isotype that has the ability to form Fc-dependent oligomers. However, F(ab′)2 fragments of the IgG3 were sufficient to agglutinate type B red blood cells; therefore, IgG3-triggered agglutination did not require oligomerization. Molecular modelling indicated that mouse IgG3 has a larger range of Fab arms than other mouse IgG subclasses and that the unique properties of mouse IgG3 are likely due to the structure of its hinge region. With a focus on applications in diagnostics, we compared the stability of IgG3 and two IgMs in formulated blood typing reagents using an accelerated storage approach and differential scanning calorimetry. IgG3 was much more stable than IgMs. Interestingly, the rapid decrease in IgM activity was caused by aggregation of the molecules and a previously unknown posttranslational proteolytic processing of the μ heavy chain. Our data point to mouse IgG3 as a potent diagnostic tool. PMID:27484487

  3. Phylogenetic studies favour the unification of Pennisetum, Cenchrus and Odontelytrum (Poaceae): a combined nuclear, plastid and morphological analysis, and nomenclatural combinations in Cenchrus.

    Science.gov (United States)

    Chemisquy, M Amelia; Giussani, Liliana M; Scataglini, María A; Kellogg, Elizabeth A; Morrone, Osvaldo

    2010-07-01

    Twenty-five genera having sterile inflorescence branches were recognized as the bristle clade within the x = 9 Paniceae (Panicoideae). Within the bristle clade, taxonomic circumscription of Cenchrus (20-25 species), Pennisetum (80-140) and the monotypic Odontelytrum is still unclear. Several criteria have been applied to characterize Cenchrus and Pennisetum, but none of these has proved satisfactory as the diagnostic characters, such as fusion of bristles in the inflorescences, show continuous variation. A phylogenetic analysis based on morphological, plastid (trnL-F, ndhF) and nuclear (knotted) data is presented for a representative species sampling of the genera. All analyses were conducted under parsimony, using heuristic searches with TBR branch swapping. Branch support was assessed with parsimony jackknifing. Based on plastid and morphological data, Pennisetum, Cenchrus and Odontelytrum were supported as a monophyletic group: the PCO clade. Only one section of Pennisetum (Brevivalvula) was supported as monophyletic. The position of P. lanatum differed among data partitions, although the combined plastid and morphology and nuclear analyses showed this species to be a member of the PCO clade. The basic chromosome number x = 9 was found to be plesiomorphic, and x = 5, 7, 8, 10 and 17 were derived states. The nuclear phylogenetic analysis revealed a reticulate pattern of relationships among Pennisetum and Cenchrus, suggesting that there are at least three different genomes. Because apomixis can be transferred among species through hybridization, its history most likely reflects crossing relationships, rather than multiple independent appearances. Due to the consistency between the present results and different phylogenetic hypotheses (including morphological, developmental and multilocus approaches), and the high support found for the PCO clade, also including the type species of the three genera, we propose unification of Pennisetum, Cenchrus and Odontelytrum. Species of Pennisetum and Odontelytrum are here transferred into Cenchrus, which has priority. Sixty-six new combinations are made here.

  4. A case of Silver–Russell syndrome (SRS): multiple pituitary hormone deficiency, lack of H19 hypomethylation and favourable growth hormone (GH) treatment response

    Indian Academy of Sciences (India)

    Zoran S. Gucev; Velibor Tasic; Aleksandra Jancevska; Ilija Kirovski

    2009-08-01

    Hypomethylation of the imprinting control region 1 (ICR1) at the IGF2/H19 locus on 11p15 is linked to Silver–Russell syndrome (SRS) and/or hemihypertrophy. This SRS patient was born in term with weight of 3500 g (50 percentile) and length 48 cm (>1 SD below the mean). He was first noticed at the age of 10 years for short stature (114.5 cm, $-3.85$ SD), relatively normal head circumference, a classic facial phenotype, hemihypertrophy (2.5 cm thinner left arm and leg in comparison to the right, asymmetric face), moderate clinodactyly and striking thinness (BMI of 15.3). At the age of 30, the body asymmetry ameliorated (1 cm thinner left arm and leg than the right), and BMI normalized (20.5 cm). Methylation analysis was performed by bisulphate treatment of DNA samples, radiolabelled PCR amplification, and digestion of the PCR products using restriction enzymes. The patient had normomethylation, and in addition hypopituitarism, with low levels of growth hormone (GH) (provocative testing before the start and after termination of GH treatment), thyroxin, TSH, FSH, LH and testosterone. The GH was given for six years, growth response was satisfactory and he reached an adult height of 166 cm. This is a first report of hypopituitarism in a patient with SRS without H19 hypomethylation. It seems that the lack of hypomethylation in this hypopituitary SRS patient is responsible, at least partly, for the favourable final adult height under GH treatment.

  5. Favourable Formations for CO{sub 2} Storage in the Almazan Basin; Formaciones Favorables para el Almacenamiento de CO{sub 2} en la Cuenca de Almazan

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz Rivas, C.; Lomba Falcon, L.

    2008-04-10

    Geological storage of carbon dioxide is one of the technological options that have been considered nowadays for global climate change mitigation. Underground CO{sub 2} storage requires the selection and identification of deep geological formations which must meet criteria for health and environmental safety in the middle-term of one thousand years. Deep permeable formations, depleted oil and gas fields, unminable coal seams and saline rocks are possible geological formations for CO{sub 2} storage. Some areas in our country have been selected to search potential CO{sub 2} reservoirs. Among these areas, sedimentary basins are highlighted because of their thick stratigraphic sequences and the availability of extensive geological data which are coming from fossil fuel exploration. In this report, the identification and selection of favourable geological formations in the Almazan basin is presented. A 3D simplified subsurface basin geological model that was based on a Geographic Information System is included as well. The report also includes suitable CO{sub 2} injection areas in the surface for the selected geological formations. Finally, a preliminary CO{sub 2} storage capacity estimation of a potential structural trap has been calculated, considering only physical CO{sub 2} trapping. This work has been undertaken in the framework of the Geological CO{sub 2} Storage Project which is within the Singular Strategic Project of the Ministry of Education and Science Generation, Capture and Storage advanced technologies of CO{sub 2}. (Author) 84 refs.

  6. Sexual harassment within the marine sciences and the ethical dilemmas of collaboration: a case study in the education and reportino methods available to scientists, students, and staff on board a federal research vessel

    Science.gov (United States)

    Ohern, J.

    2016-02-01

    Within the Science, technology, engineering, and math (STEM) disciplines, a disparity between male and female involvement persists on the order of about 3:1. While roughly 40% of men with STEM degrees go on to pursue STEM jobs, just 26% of women with STEM degrees hold jobs within the STEM field. There are a number of contributing factors to these disparities, but one pernicious factor is the issue of sexual harassment and discrimination. For the marine sciences this is an especially concerning issue because our field research frequently takes place hundreds of miles offshore. Despite education and policy initiatives, sexual harassment pervades many research vessels and is often never addressed, discouraging female involvement and limiting the opportunities available to women. Ethical dilemmas develop when administrators do not want to risk limited field schedules and funding while investigations are conducted and harassment issues resolved. Additionally, scientists and staff often collaborate between institutions, benefitting science but blurring the lines of responsibility. In one such case, administrators within a federal research office declined to report sexual harassment taking place between contracted crew members on their research vessel. The lengthy review process and lack of culpability discourages reporting of sexual harassment and allows problematic situations to occur. This case study reviews the reporting mechanisms currently in place, the barriers to reporting, and the proposed methods for more effectively resolving discriminatory workplaces. Collaboration within marine science is an absolute necessity, and our research benefits from diverse working groups. As marine scientists we have an ethical responsibility to ensure safe working environments for both the scientists and the staff who make our research possible.

  7. Advanced Metering Implementations - A Perspective from Federal Sector

    Energy Technology Data Exchange (ETDEWEB)

    Eaarni, Shankar

    2014-08-11

    Federal mandate (EPACT 2005) requires that federal buildings install advanced electrical meters-meters capable of providing data at least daily and measuring the consumption of electricity at least hourly. This work presents selected advanced metering implementations to understand some of the existing practices related to data capture and to understand how the data is being translated into information and knowledge that can be used to improve building energy and operational performance to meet federal energy reduction mandates. This study highlights case studies to represent some of the various actions that are being taken based on the data that are being collected to improve overall energy performance of these buildings. Some of these actions include- individualized tenant billing and energy forecasting, benchmarking, identifying energy conservation measures, measurement and verification.

  8. Assessing the Feasibility of Developing a Federated ERP System

    CERN Document Server

    Gall, Michael; Bjerre, Mogens; 10.5121/ijmit.2011.3302

    2011-01-01

    In past years ERP Systems have become one of the main components within the corporate IT structure. Several problems exist around implementing and operating these systems within companies. In the literature one can find several studies about the problems arising during the implementation of an ERP system. The main problem areas are around the complexity of ERP systems. One vision to overcome some of these problems is federated ERP. Federated ERP systems are built of components from different vendors, which are distributed within a network. All components act as one single ERP system from the user perspective. The decreased complexity of such a system would require lower installation and maintenance cost. Additional, only the components which are needed to cover the company's business processes would be used. Several theories around this concept exist, but a feasibility assessment of developing a federated ERP system has not been done yet. Based on a literary analysis of existing methods for feasibility studie...

  9. The politics of federal environmental education policy

    Science.gov (United States)

    Crouch, Richard Craig

    Both environmental governance1 and education governance 2 occupy contested territory in contemporary US political discourse. Environmental education (EE) policy has emerged at this intersection and taken on aspects of both controversies. Central to debates surrounding environmental education are still unresolved issues concerning the role of the federal government in education, the role of education in citizen-making, and the role of the public in environmental governance. As a case study of the politics of environmental education policy, I explore these issues as they relate to the National Environmental Education Act of 1990,3 attempts at its reauthorization, its continued appropriations, and its current state of policy stasis. The political controversy over the federal role in environmental education is an appropriate case study of environmental education politics insofar as it reflects the different positions held by actor groups with regard to the definition, efficacy, and legitimacy of environmental education. At the core of these debates, as we will see, is a definitional crisis---that is, there is no common understanding across the relevant actor groups as to what environmental education is, or should be. I suggest here that this definitional issue can be best understood as having technical, ideological, and structural components4---all of which are mutually reinforcing and thus perpetuate the stasis in federal environmental education policy. 1I rely on Durant, Fiorino and O'leary's definition of environmental governance in Environmental Governance Reconsidered ; "In the term environmental governance, we refer to the increasingly collaborative nature of [environmental and natural resource] policy formulation and implementation. In this vein, a wide array of third parties (for example, actors in the profit sector, the nonprofit sector, and civic society), in addition to government agencies, comprise non hierarchical networks of actors wielding a variety of

  10. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 19. The U. S. Government Technical Report and the Transfer of Federally Funded Aerospace R&D: An Analysis of Five Studies

    Science.gov (United States)

    1994-01-01

    Merrill. D. W. Stevenson 1976 McClure, C. R. "The Federal Technical Report Literature: Research Needs and 1988 Issues." Government Information Quarterly 5...T. E., "The NASA/DoD Aerospace Knowledge Diffusion Research J. M. Kennedy, and Project." Government Information Quarterly 8(2): 219-233. R. 0

  11. An Analysis of Citizen Participation Programs Relating to the Federal Water Pollution Control Act Amendments of 1972 (P.L. 92-500): Case Studies of the Washington County Project; State of Wisconsin; and Dane County, Wisconsin Programs.

    Science.gov (United States)

    Salmon, Elizabeth E.

    The thesis, which presents an analysis of three Wisconsin citizen participation programs relating to the Federal Water Pollution Control Act Amendments of 1972 (Public Law 92-500), has identified the adult education role in teaching and applying skills, promoting growth in governmental understanding, assisting in public planning and…

  12. 48 CFR 29.203 - Other Federal tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Other Federal tax exemptions. 29.203 Section 29.203 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES Federal Excise Taxes 29.203 Other Federal tax exemptions....

  13. ESTUDO DA ARBORIZAÇÃO E DAS ÁREAS VERDES DO CAMPUS II DA UNIVERSIDADE FEDERAL DE GOIÁS STUDY OF THE ARBORIZATION AND GREEN AREAS OF THE CAMPUS II OF THE FEDERAL UNIVERSITY OF GOIÁS, BRAZIL

    Directory of Open Access Journals (Sweden)

    José Ângelo Rizzo

    2007-09-01

    Full Text Available

    Em continuidade ao estudo das áreas verdes do Campus II da UFG, desenvolveu-se um trabalho para verificar a situação da arborização localizada no referido Campus. O local para o estudo da vegetação consistiu nos espaços entre prédios, sistema viário, praças, estacionamentos e mini-bosque e para a localização dos mesmos usou-se uma planta aerofotogramétrica de escala aproximada de 1:5000. As plantas foram locadas e identificadas. As espécies nativas são remanescentes da cobertura da Mata Semidecídua ocorrente no local, tendo como destaque Apuleia molaris Spruce (garapa, Anadenanthera perigrina L. (angico, Cedrela fissilis Vell. (cedro e Tabebuia serratifolia (Vahl. Nichols (ipê amarelo e outras. As espécies exóticas e algumas da flora do Estado de Goiás têm como representantes Spathodea campanulata Beauv. (espatódea, Delonix regia Rafin (flamboyant, Pachira aquatica Aublet (munguba, Caesalpinia echinata Lam. (pau-brasil e Syagrus oleracea (Mart. Becc. (guariroba. O total de 1.389 indivíduos levantados está distribuído em 43 famílias e 84 gêneros. O trabalho demonstrou que algumas espécies não foram plantadas em locais adequados em razão do porte, sistema radicular e queda de folhas. O estudo desenvolvido permitirá ampliação, melhoria na arborização e recomposição das áreas verdes do Campus II, bem como contribuirá para os futuros projetos paisagísticos.

    Continuing the study of the green areas of the Campus II of the Federal University of Goiás it was developed a research in order to check the situation of the arborization at Campus. The sites of the present study consisted of spaces

  14. Policiamento democrático no Brasil: enquadramentos teóricos e desilusões empíricas: um estudo das polícias do Distrito Federal = Democratic policing in Brazil: theoretical framework and empirical disappointments: a study of Distrito Federal police

    Directory of Open Access Journals (Sweden)

    Rocha, Alexandre Pereira da

    2013-01-01

    Full Text Available Este artigo realiza levantamento teórico sobre policiamento democrático, destacando os aspectos da responsiveness e accountability na atividade policial. Procura demonstrar que as dificuldades de um policiamento democrático no Brasil decorrem de enclaves nos arranjos institucional, organizacional e cultural do sistema policial, bem como do processo de democratização. A partir do estudo das polícias civil e militar do Distrito Federal, discute a dificuldade de se formar polícias democráticas no Brasil em virtude de contradições internas às próprias organizações policiais. Ao fim, cogita a necessidade de reformas das polícias não só para reforçar a eficácia delas no controle da criminalidade, mas, sobretudo para inseri-las num contexto democrático

  15. Federal Pioneers: Environmentally Preferable Purchasing Success Stories from the Federal Government

    Science.gov (United States)

    The federal government purchases more than $200 billion worth of goods and services each year; purchasing decisions can have important environmental consequences, federal agencies are considering some environmental impacts when buying goods and services.

  16. Federation of Malaysia. Country profile.

    Science.gov (United States)

    Newcomb, L

    1985-01-01

    The 1984 population of Malaysia has been estimated at 14.7 million and the population growth rate averaged 2.3% in 1970-80. Population growth is officially encouraged to form a substantial home market for economic development. Toward this end, the 1985 budget has increased tax deductions for families with 5 children. The capital city of Kuala Lumpur is the largest metropolitan area (1 million population) and the Federal Territory is the most densely populated region. Immigration is strictly controlled by the government, and the percentage of foreign-born citizens was 5% in 1980. China, India, and Pakistan are decreasing in importance as countries of origin. Internal mobility, however, is increasing. Rural-rural migration accounted for 45% of internal migration in 1970-80 and was largely motivated by family reasons. Only 7% of Malaysians are estimated to move in search of work. Racial tensions led the government to grant special economic privileges to native-born Islamic Malays. The greatest proportion of the population is centered in the lowest age groups. The percentage of females 15-29 years of age rose from 26% in 1970 to 30% in 1980 and is expected to continue to rise. Fertility is on the decline. The majority of households in the country involve nuclear families. There has been an increase in the number of men and women who delay marriage or remain single. Education is widely available for children aged 6-15 years and those who meet certain academic standards receive free education up to age 19 years. The current labor force is estimated at 5.4 million, with an annual growth rate of 3.1%. Malaysia's per capita income (US $1860 in 1982) is among the highest in Southeast Asia and the gross national product increased by an average annual rate of 8% in 1970-81. The government plans to move toward the development of heavier industries and more manufacturing concerns.

  17. The New Federalism: State Policies Regarding Embryonic Stem Cell Research.

    Science.gov (United States)

    Acosta, Nefi D; Golub, Sidney H

    2016-09-01

    Stem cell policy in the United States is an amalgam of federal and state policies. The scientific development of human pluripotent embryonic stem cells (ESCs) triggered a contentious national stem cell policy debate during the administration of President George W. Bush. The Bush "compromise" that allowed federal funding to study only a very limited number of ESC derived cell lines did not satisfy either the researchers or the patient advocates who saw great medical potential being stifled. Neither more restrictive legislation nor expansion of federal funding proved politically possible and the federal impasse opened the door for a variety of state-based experiments. In 2004, California became the largest and most influential state venture into stem cell research by passing "Prop 71," a voter initiative that created a new stem cell agency and funded it with $3 billion. Several states followed suit with similar programs to protect the right of investigators to do stem cell research and in some cases to invest state funding in such projects. Other states devised legislation to restrict stem cell research and in five states, criminal penalties were included. Thus, the US stem cell policy is a patchwork of multiple, often conflicting, state and federal policies.

  18. FEDERALISM IN ETHIOPIA AND FOREIGN RELATIONS ...

    African Journals Online (AJOL)

    milkii

    Louis Henkin, in supporting the constitutionally centralized foreign .... federation by projecting its identity internationally, gaining ... Halberstam, The Foreign Affairs on Federal system: A National perspective on the ... and maximize their residents' way of life. ... growth; and tourism – all of which are highly competitive globally.

  19. 76 FR 10410 - Sunshine Federal Register Notice

    Science.gov (United States)

    2011-02-24

    ... March 28, 2011--Tentative Tuesday, March 29, 2011 9 a.m. Briefing on Small Modular Reactors (Public... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Sunshine Federal Register Notice AGENCY: Nuclear Regulatory Commission. DATES: Weeks of...

  20. 76 FR 11290 - Sunshine Federal Register Notice

    Science.gov (United States)

    2011-03-01

    ... Tuesday, March 29, 2011 9 a.m. Briefing on Small Modular Reactors (Public Meeting) (Contact: Stephanie... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Sunshine Federal Register Notice AGENCY HOLDING THE MEETINGS: Nuclear Regulatory Commission....