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Sample records for favorable con quimioterapia

  1. Linfoma hepático primario: Evolución favorable con quimioterapia combinada con rituximab Primary hepatic lymphoma: favorable outcome with chemotherapy plus rituximab

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    I. Serrano-Navarro

    2008-11-01

    Full Text Available Comunicamos el caso de una paciente con un linfoma hepático primario tratado con éxito con quimioterapia combinada con rituximab. Utilizando los "encabezamientos estándar para búsquedas bibliográficas informatizadas" (Medical Subject Heading revisamos los casos publicados hasta la fecha de esta infrecuente entidad.This article describes the case of a patient with a non-Hodgkin primary hepatic lymphoma who was successfully treated with chemotherapy combined with rituximab. Using the Medical Subject Headings the published reports of this rare entity were reviewed.

  2. Vivencias psicosociales reveladas por niños que reciben tratamiento con quimioterapia por cáncer

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    BLANCA CECILIA VANEGAS DE AHOGADO; MARÍA ELVIRA BELTRÁN HERRERA; VIVIANA CIFUENTES GIL; YULIETH ALEJANDRA DUARTE; JIMMY JULIÁN MONTOYA; JOHANNA MARCELA RIVERA ZABALA; MARÍA MERCEDES LAFAURIE VILLAMIL

    2009-01-01

    Se realizó un estudio cualitativo con el propósito de descubrir las vivencias psicosociales de niños y niñas de 9 a 12 años que recibían tratamiento con quimioterapia por cáncer. La recolección de la información se hizo mediante encuentros lúdicos con el apoyo de algunas preguntas básicas que facilitaron las revelaciones narrativas. Tres aspectos se destacan en los hallazgos del estudio: vivencias desfavorables, vivencias relacionadas con la autoestima y vivencias favorables; las dos primeras...

  3. Profilaxis primaria para tromboembolismo venoso en pacientes ambulatorios con cáncer sometidos a quimioterapia

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    2013-07-01

    Conclusiones de los autores: La tromboprofilaxis primaria con HBPM redujo significativamente la incidencia del TEV sintomático en los pacientes ambulatorios con cáncer tratados con quimioterapia. Sin embargo, la ausencia de poder estadístico obstaculiza la posibilidad de establecer conclusiones definitivas sobre los efectos en cuanto a los resultados principales de seguridad, lo cual obliga a la realización de estudios adicionales para determinar el cociente riesgos/beneficios de la HBPM en este contexto.

  4. Vivir con cáncer: una experiencia de cambios profundos provocados por la quimioterapia

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    Paula Jaman-Mewes

    2014-01-01

    Full Text Available Objetivo: develar las experiencias de mujeres chilenas con cáncer en tratamiento con quimioterapia. Materiales y método: estudio de investigación cualitativa fenomenológica según el pensamiento filosófico de Martín Heidegger. Se entrevistaron en profundidad a 10 mujeres entre 45 y 64 años, con diferentes diagnósticos de cáncer en tratamiento con quimioterapia. El análisis se realizó basado en el método de Streubert y Carpenter, triangulando con un investigador experto. Resultados: la experiencia de vivir con cáncer y con quimio- terapia significa estar “viviendo con un tratamiento que provoca cambios profundos en la vida de las mujeres”, siendo esta una categoría comprensiva esencial del estudio que contiene cuatro unidades de significados: 1 cambios en todas las dimensiones del “ser” de las mujeres tanto a nivel corporal como emocional y espiritual; 2 cambios en el “ser-sí-misma”: antes y durante la quimioterapia; 3 cambios de “ser” en el mundo; 4 cambios en la familia. Conclusiones: la comprensión en profundidad de lo vivido por las mujeres de este estudio confirma lo publicado en la literatura, y se constituye en un saber comprensivo que puede servir de guía para realizar cuidados de enfermería oncológicos humanos y personalizados basados en las necesidades de cada persona.

  5. Estudio prospectivo del funcionamiento cognitivo en pacientes de cáncer de colon tratados con quimioterapia

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    López Santiago, Sonia

    2012-01-01

    El objetivo de esta tesis es investigar los cambios en rendimiento cognitivo de pacientes de cáncer de colon tratados con quimioterapia adyuvante. El método ha sido el estudio longitudinal unifactorial de tres medidas (T1: antes de la quimioterapia, T2: al finalizar el tratamiento y T3 seis meses después de T2); se explora: memoria verbal, función ejecutiva y habilidad psicomotora y variables moduladoras (ansiedad, depresión, astenia y calidad de vida). Muestra: 77 participantes, 63% varones,...

  6. Vivencias psicosociales reveladas por niños que reciben tratamiento con quimioterapia por cáncer

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    BLANCA CECILIA VANEGAS DE AHOGADO

    2009-12-01

    Full Text Available Se realizó un estudio cualitativo con el propósito de descubrir las vivencias psicosociales de niños y niñas de 9 a 12 años que recibían tratamiento con quimioterapia por cáncer. La recolección de la información se hizo mediante encuentros lúdicos con el apoyo de algunas preguntas básicas que facilitaron las revelaciones narrativas. Tres aspectos se destacan en los hallazgos del estudio: vivencias desfavorables, vivencias relacionadas con la autoestima y vivencias favorables; las dos primeras, de diversa manera, afectan en estos niños su vida personal, familiar, escolar y, en general, todo su entorno. Es de resaltar que, como consecuencia de la caída del cabello, con frecuencia han sido objeto de burla y de rechazo por sus compañeros de estudio, lo que produce el más notorio efecto sobre su autoimagen; por otra parte, el ausentismo escolar conlleva dificultades académicas y sentimientos de tristeza en estos niños, situación que empeora cuando, por motivos de tratamiento, su lugar de residencia está alejado de la ciudad, viéndose sometidos a largos periodos de separación, no solo de su familia sino de sus pares. Se concluye que la mayor parte de las revelaciones son impactantes por su gran contenido de sufrimiento y dolor para estos niños, lo que demuestra la urgencia de retomar los hallazgos del estudio para orientar el cuidado de enfermería de manera más integral y apoyar para que se haga lo propio en el hogar y en las instituciones educativas.

  7. Alteraciones de la calidad de vida en mujeres con cáncer de mama al recibir quimioterapia

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    Castillo Hidalgo, Marina

    2015-01-01

    Introducción: La calidad de vida es „‟la suma de factores físicos, emocionales y sociales que contribuyen al bienestar de una persona. Implica que, para medir ésta, deben medirse todos y cada uno de los factores que la componen. ’’ Es fundamental estudiar y valorar la calidad de vida de las mujeres con cáncer de mama que se someten a quimioterapia, ya que, tras analizar los diferentes factores, nos permite saber cuál es el impacto y los efectos secundarios que les provoca tanto la enfermedad ...

  8. Factores pronósticos y predictivos de respuesta en pacientes con carcinoma de vejiga localmente avanzado tratados con quimioterapia neoadyuvante

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    Céliz, Pamela

    2012-01-01

    La cistectomía radical es el tratamiento de elección en pacientes con carcinoma de vejiga localmente avanzado. Sin embargo, más del 50% de los pacientes presentan recurrencias y fallecen por la enfermedad. La quimioterapia neoadyuvante ha demostrado un beneficio modesto en estos pacientes, más significativo en pacientes con respuesta patológica completa tras el tratamiento. Sin embargo, aun no se ha identificado en que pacientes se obtiene un mayor beneficio. El análisis de genes que particip...

  9. A esperança da pessoa com cancro: estudo em contexto de quimioterapia La esperanza de la persona con cáncer: estudio en el contexto de quimioterapia Hope of cancer patients: research in the context of chemotherapy

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    Sara Pinto

    2012-07-01

    Full Text Available Contexto: a esperança é um conceito que ajuda a pessoa a lidar com a crise de uma forma mais eficaz. A evidência científica evoca a sua importância no âmbito dos cuidados paliativos, defendendo que esperanças realistas ajudam a pessoa a viver o tempo que resta da melhor forma possível. Objetivos: analisar o índice de esperança de uma amostra de doentes submetidos a quimioterapia e compreender a influência de algumas variáveis sociodemográficas, clínicas e religiosas sobre o mesmo. Metodologia: estudo observacional, transversal, do tipo exploratório, descritivo-correlacional, numa amostra de 92 doentes oncológicos em quimioterapia. Utilizou-se o Herth Hope Index-PT e os dados foram analisados pelo programa Statistical Package for the Social Sciences, versão 18. Resultados: os inquiridos apresentam índices de esperança elevados (média=29.61 pontos. O tempo de diagnóstico e o tempo em quimioterapia influenciam a esperança (p Contexto: la esperanza es un concepto que ayuda a las personas a lidiar con la crisis de manera más eficaz. La evidencia científica evoca su importancia en el ámbito de los cuidados paliativos, dado que las esperanzas realistas ayudan a la persona a vivir el tiempo que le queda de la mejor manera posible. Objetivos: evaluar el nivel de esperanza de una muestra de pacientes en quimioterapia y comprender la influencia de algunas variables sociodemográficas, clínicas y religiosas sobre éste. Metodología: estudio observacional, transversal, exploratorio, descriptivo-correlacional en una muestra de 92 pacientes con cáncer y sometidos a quimioterapia. Se utilizó el Índice de Esperanza de Herth-PT y los datos fueron analizados mediante el programa Statistical Package for the Social Sciences, versión 18. Resultados: los encuestados presentan un alto nivel de esperanza (media = 29.61puntos. La duración del diagnóstico y de la quimioterapia influyen en los niveles de esperanza (p Background: hope is a

  10. Qualidade de vida do paciente com câncer colorretal em quimioterapia ambulatorial Calidad de vida de los pacientes con cáncer colorrectal en quimioterapia ambulatoria Quality of life of patients with colorectal cancer receiving outpatient chemotherapy

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    Patrícia Lemos Chaves

    2011-12-01

    Full Text Available Trata-se de um estudo transversal com abordagem quantitativa descritiva, no qual buscou-se avaliar a qualidade de vida (QV do paciente com câncer colorretal em quimioterapia ambulatorial. A pesquisa foi desenvolvida em uma Unidade de Quimioterapia Ambulatorial em um hospital do sul do Brasil, cujos pacientes eram portadores do diagnóstico de câncer colorretal e foram submetidos ao tratamento com o Protocolo 5FU. A amostra contou com 48 participantes que estavam em tratamento quimioterápico por um período de seis meses. Utilizou-se como instrumento um questionário, o WHOQOL-Bref. Nos resultados encontrados, prevaleceu a idade de 50 anos ou mais e possuíam no mínimo um mês e no máximo 11 meses de tratamento. Os domínios do WHOQOL-Bref afetados mais significativamente foram o psicológico e o das relações sociais, respectivamente, havendo diferença nas respostas quanto à QV geral naqueles que estavam no 1º ciclo de tratamento daqueles que já se encontravam no 6º ciclo.Este es un estudio transversal con un enfoque cuantitativo descriptivo, que buscó evaluar la calidad de vida (QOL de los pacientes con cáncer colorrectal en quimioterapia ambulatorial. La investigación fue desarrollada en una unidad de quimioterapia Outpatient Clinic en un hospital del sur de Brasil, cuyos pacientes tenían el diagnóstico de cáncer colorrectal y que se presentaron al tratamiento con el Protocolo 5FU. La muestra ha contado con 48 participantes que se encontraban en quimioterapia por un período de 6 meses. Se utilizó como instrumento un cuestionario, WHOQOL-Bref. En los resultados, prevaleció la edad de 50 años o más y tenían al menos un mes y un máximo de 11 meses de tratamiento. Las áreas de WHOQOL-Bref afectadas más significativamente eran las esferas psicológica y las relaciones sociales, respectivamente, con diferencia en las respuestas de QOL general las que estaban en 1 ciclo de aquellos que ya estaban en el ciclo 6TH.This is a

  11. Programa educativo dirigido a pacientes con cáncer de mama que reciben quimioterapia ambulatoria en el Centro Oncológico Estatal ISSEMYM

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    Gutierrez García, Edna Jannet

    2014-01-01

    El cáncer de mama es un crecimiento irregular de células anómalas del tejido mamario; en México es la segunda causa de muerte. El Centro Oncológico Estatal (COE) del ISSEMYM brinda tratamiento al 70% de la población femenina que es diagnosticada con este padecimiento, incluye tanto a las pacientes derechohabientes como a las pacientes atendidas en el programa de seguro popular, diagnosticadas en su unidad adscrita; para fines de esta investigación, se consideró únicamente la quimioterapia...

  12. Vivencias psicosociales reveladas por niños que reciben tratamiento con quimioterapia por cáncer Vivências psicossociais de crianças com tratamento de quimioterapia por câncer Psychosocial experiences of children receiving chemotherapy for cancer

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    BLANCA CECILIA VANEGAS DE AHOGADO

    Full Text Available Se realizó un estudio cualitativo con el propósito de descubrir las vivencias psicosociales de niños y niñas de 9 a 12 años que recibían tratamiento con quimioterapia por cáncer. La recolección de la información se hizo mediante encuentros lúdicos con el apoyo de algunas preguntas básicas que facilitaron las revelaciones narrativas. Tres aspectos se destacan en los hallazgos del estudio: vivencias desfavorables, vivencias relacionadas con la autoestima y vivencias favorables; las dos primeras, de diversa manera, afectan en estos niños su vida personal, familiar, escolar y, en general, todo su entorno. Es de resaltar que, como consecuencia de la caída del cabello, con frecuencia han sido objeto de burla y de rechazo por sus compañeros de estudio, lo que produce el más notorio efecto sobre su autoimagen; por otra parte, el ausentismo escolar conlleva dificultades académicas y sentimientos de tristeza en estos niños, situación que empeora cuando, por motivos de tratamiento, su lugar de residencia está alejado de la ciudad, viéndose sometidos a largos periodos de separación, no solo de su familia sino de sus pares. Se concluye que la mayor parte de las revelaciones son impactantes por su gran contenido de sufrimiento y dolor para estos niños, lo que demuestra la urgencia de retomar los hallazgos del estudio para orientar el cuidado de enfermería de manera más integral y apoyar para que se haga lo propio en el hogar y en las instituciones educativas.O presente trabalho corresponde à elaboração de um estudo qualitativo que visa descobrir as vivências psicossociais de crianças entre 9 e 12 anos sendo tratadas com quimioterapia por câncer. A informação foi compilada através de encontros lúdicos suportados por algumas perguntas básicas que facilitaram as revelações narrativas. Entre os achados do estudo destacam-se três aspectos: vivencias desfavoráveis, vivências relacionadas com a autoestima e vivências favor

  13. Vivencias psicosociales reveladas por niños que reciben tratamiento con quimioterapia por cáncer Psychosocial experiences of children receiving chemotherapy for cancer Vivências psicossociais de crianças com tratamento de quimioterapia por câncer

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    RIVERA ZABALA JOHANNA MARCELA

    2009-12-01

    Full Text Available Se realizó un estudio cualitativo con el propósito de descubrir las vivencias psicosociales de niños y niñas de 9 a 12 años que recibían tratamiento con quimioterapia por cáncer. La recolección de la información se hizo mediante encuentros lúdicos con el apoyo de algunas preguntas básicas que facilitaron las revelaciones narrativas. Tres aspectos se destacan en los hallazgos del estudio: vivencias desfavorables, vivencias relacionadas con la autoestima y vivencias favorables; las dos primeras, de diversa manera, afectan en estos niños su vida personal, familiar, escolar y, en general, todo su entorno. Es de resaltar que, como consecuencia de la caída del cabello, con frecuencia han sido objeto de burla y de rechazo por sus compañeros de estudio, lo que produce el más notorio efecto sobre su autoimagen; por otra parte, el ausentismo escolar conlleva dificultades académicas y sentimientos de tristeza en estos niños, situación que empeora cuando, por motivos de tratamiento, su lugar de residencia está alejado de la ciudad, viéndose sometidos a largos periodos de separación, no solo de su familia sino de sus pares. Se concluye que la mayor parte de las revelaciones son impactantes por su gran contenido de sufrimiento y dolor para estos niños, lo que demuestra la urgencia de retomar los hallazgos del estudio para orientar el cuidado de enfermería de manera más integral y apoyar para que se haga lo propio en el hogar y en las instituciones educativas.A qualitative study was carried out in order to discover psychosocial experiences of boys and girls receiving chemotherapy treatment for cancer. Information was collected through ludic encounters with the support of some basic questions to facilitate narrative disclosures. Three aspects stand out among findings in the study: unfavorable experiences, experiences related to self esteem and favorable experiences; the first two, in different ways, affect boys and girls’ personal

  14. Diferencias de género en la percepción de estrés y estrategias de afrontamiento en pacientes con cáncer colorrectal que reciben quimioterapia

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    Sonia Betzabeth Ticona Benavente

    2015-01-01

    Full Text Available Objetivo: verificar si existen diferencias de género en la percepción de estrés y estrategias de afrontamiento; identificar las estra- tegias de afrontamiento y las variables clínicas y sociodemográficas que influyen sobre el estrés de pacientes con cáncer colorrectal en quimioterapia. Materiales y métodos: estudio transversal con abordaje cuantitativo. Conformaron la muestra 100 pacientes, 47 mujeres y 53 hombres, de la unidad ambulatoria de quimioterapia del AC Camargo Cancer Center , Brasil. Se utilizó la Escala de Estrés Percibido (PSS-10 e Inventario de Estrategias de Coping. El análisis estadístico fue mediante el test-t, correlación de Pearson y regresión linear con 95 % de intervalo de confianza. Resultados: Las mujeres tuvieron más altos niveles de estrés (p = 0,029, y no hubo diferencia de género en las estrategias de afrontamiento. Adicionalmente, identificamos influencia positiva al estrés percibido en pacientes comprometidos con otras enfermedades ( β = 3,50, p = 0,00, género femenino ( β = 3,15, p = 0,04, viudos ( β = 9,19, p = 0,00, tratamiento con fluorou- racil ( β = 6,36, p = 0,00, que usan estrategias de dominio del afrontamiento ( β = 0,70, p = 0,00, aceptación de responsabilidad ( β = 0,45, p = 0,01 y estadio del tumor III ( β = 4,03, p = 0,05. Conclusiones: el equipo de enfermería oncológica, por estar en estrecho y prolongado contacto con los pacientes, debe considerar el género y las características clínicas y sociodemográficas de cada paciente durante su cuidado.

  15. Evaluación del eje hipotálamo hipófisis adrenal después de la quimioterapia de inducción en niños con Leucemia Linfoide Aguda (LLA) / Evaluation of the hypothalamo - pituitary- adrenal axis after induction chemotherapy in children with acute lymphoid leukemia (ALL)

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    Acevedo Sedano, Gizeth Lorena

    2011-01-01

    Antecedentes: La insuficiencia suprarrenal no ha sido en cuenta en los niños que reciben dosis altas de esteroides, como los de la quimioterapia de inducción para Leucemia Linfoide Aguda (LLA). Algunos autores han reportado una incidencia de disfuncion suprarrenal entre 46% a 81,5% en este grupo de pacientes. Objetivos: Evaluar la frecuencia de insuficiencia suprarrenal en pacientes pediátricos con LLA después de recibir quimioterapia de inducción que incluye esteroides a...

  16. Rectum neoplasms treatment advanced with radio and chemotherapy before - surgery; Tratamiento de cancer de recto localmente avanzado con radioterapia y quimioterapia preoperatoria

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    Luongo Cespedes, A; Aguiar Vitacca, S [and others

    1993-12-01

    In Uruguay the colorectal neoplasms has a can rate of mobility. The surgery has 13-26% local recurrence. The irradiation before surgery has demonstrated to improve the resect and the local control.The objective of this protocol it is to decrease the percentage of local relapse , using radiotherapy(RT) before surgery and concomitant chemotherapy that potencies the effect of the RT, improvement this way the therapeutic quotient (AU) [Spanish] En Uruguay el cancer colorrectal tiene una lata tasa de mortalidad.La cirugia exclusiva,tiene 13-26 % de recurrencias locales.La irradiacion preoperatoria ha demostrado mejorar la resecabilidad y el control local.El objetivo de este protocolo es disminuir el porcentaje de recidiva local,utilizando radioterapia(RT) preoperatoria y quimioterapia concomitante que potencie el efecto de la RT,mejorando asi el cociente terapeutico (AU)

  17. Monitoramento e avaliação dos efeitos colaterais da quimioterapia em pacientes com câncer de cólon Monitoreo y evaluación de los efectos colaterales de la quimioterapia en pacientes con neoplasia de colon Monitoring and evaluation of side effects of chemotherapy in patients with colon cancer

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    Elizabeth Pinto Magalhães de Almeida

    2004-10-01

    Full Text Available Este estudo objetivou monitorar e avaliar a ocorrência e grau de intensidade da náusea, vômito e diarréia em pacientes com neoplasia de cólon, submetidos à quimioterapia ambulatorial, que receberam informações de enfermagem para o manejo desses sintomas. Fizeram parte do estudo 17 pacientes tratados com 5-Fluorouracil e baixas doses de ácido folínico, no Ambulatório de Quimioterapia de Adultos do Hospital São Paulo/Universidade Federal de São Paulo. Foram elaborados instrumentos para o registro da ocorrência e grau de intensidade desses sintomas e folhetos com informações sobre o seu manejo. As informações e o seguimento foram realizados pela enfermeira do setor, durante as consultas de enfermagem. Os resultados evidenciaram que a maioria dos pacientes (82,4% apresentou pelo menos um dos sinais e sintomas estudados, entre o primeiro e o 21º dias do ciclo de tratamento. A náusea foi o sintoma mais freqüente (76,5%, com pico no 4º e 5º dias do ciclo, seguida da diarréia (70,5%, com pico no 7º dia e, por último o vômito (53,0%, com pico no 5º dia. Quanto ao grau de intensidade desses sintomas, a maioria dos pacientes situou-se no grau 1, estabelecido como aceitável para o estudo, indicando que as orientações de enfermagem e o acompanhamento contínuo contribuíram para a maior efetividade do manejo desses sintomas por parte dos pacientes.Este estudio tuvo como objetivo monitorear y evaluar la frecuencia y el grado de intensidad de la náusea, vómito y diarrea en pacientes con neoplasia de colon sometidos a quimioterapia ambulatoria que recibieron información de enfermería para el manejo de esos síntomas. Participaron del estudio 17 pacientes tratados con 5-Fluorouracil y bajas dosis de ácido folínico, en el Ambulatorio de Quimioterapia de Adultos del Hospital São Paulo / Universidad Federal de São Paulo, Brasil. Para el registro de la frecuencia e intensidad de esos síntomas fueron elaborados instrumentos y

  18. Quimioterapia e anestesia

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    Márcio Augusto Lacerda

    2001-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A quimioterapia é um dos principais tipos de tratamento oferecido a pacientes com câncer, mas ainda causam importantes efeitos colaterais, reversíveis ou não. Para os anestesiologistas, conhecer estas drogas, complicações e interações medicamentosas, é de importância capital em cirurgias com pacientes em tratamento de neoplasias. CONTEÚDO: Nesta revisão apresentam-se os diferentes tipos de quimioterápicos atualmente utilizados, a classificação farmacológica, repercussões orgânicas, interações com outras substâncias, e a conduta anestésica mais apropriada frente a elas, objetivando reduzir a morbi-mortalidade perioperatória nestes pacientes. CONCLUSÕES: O conhecimento, pelo anestesiologista, das formas de tratamento, das características farmacológicas destas substâncias, seus efeitos adversos, lesões estruturais e possíveis interações medicamentosas por elas geradas e potencializadas pelas várias técnicas anestésicas hoje empregadas, pode certamente reduzir a morbi-mortalidade peri-operatória destes pacientes.

  19. Anestesia para peritonectomia com quimioterapia intraperitoneal hipertérmica transoperatória: relato de caso Anestesia para peritonectomía con quimioterapia intraperitoneal hipertérmica transoperatória: relato de caso Anesthesia for peritonectomy with hyperthermic intraoperative peritoneal chemotherapy: case report

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    Giorgio Pretto

    2010-10-01

    ínicos, laboratoriais, reconhecimento e tratamento de qualquer alteraçãoJUSTIFICATIVA Y OBJETIVOS: El seudomixoma peritoneal es una condición rara, relacionada con neoplasias epiteliales de apéndice y ovario. El tratamiento de elección es la citorreducción quirúrgica, peritonectomía y quimioterapia intraabdominal hipertérmica transoperatoria (QIAHT. Le concierne al anestesiólogo mantener la normovolemia, normotermia, el manejo del dolor postoperatorio y el estado de coagulación. El objetivo de este estudio fue describir un caso de peritonectomía con QIAHT. RELATO DEL CASO: Paciente femenina, 37 años, ASA I, con apendicectomía hace 3 meses, con laudo anatomopatológico de cistoadenoma mucinoso. Después de revisada la pieza, quedó evidenciado el seudomixoma peritoneal, con una indicación de peritonectomía con QIAHT. Se instaló un catéter epidural (T11-T12, dosis de test y morfina. Se procedió entonces a la inducción anestésica con remifentanil 0,4 µg.kg-1.min-1, propofol y rocuronio, además de intubación orotraqueal en secuencia rápida. El mantenimiento se hizo con remifentanil, sevoflurano y rocuronio, conforme al TOF. Fueron administrados vía catéter epidural 10 minutos antes de la incisión ropivacaína 50 mg y fentanil 100 µg en 10 mL. Durante toda la cirugía, PVC, SpO2, FeCO2, la temperatura, frecuencia cardíaca, PAM y diuresis mantuvieron valores estables dentro de la normalidad, inclusive en el período de la QIAHT. Reducción en el hematocrito y SvO2, el ensanchamiento del TAP y la plaquetopenia fueron corregidos con la administración de hemocomponentes. Después de 13 horas de cirugía, la paciente fue admitida en la UCI en ventilación controlada. Se extubó el 1º día del postoperatorio, con alta al 17º día del ingreso. CONCLUSIONES: La citorreducción quirúrgica y la peritonectomía con QIAHT surgieron en la década de 1990, con diversos estudios revelando el aumento significativo de la sobrevida. En función de la complejidad del

  20. Desenvolvimento de instrumento de coleta de dados de enfermagem para pacientes com câncer de pulmão em quimioterapia ambulatorial Desarrollo de instrumento de recogida de datos de enfermería para pacientes con cáncer de pulmón en quimioterapia ambulatoria Developing a nursing data colleting instrument to patients with lung cancer treated by chemotherapy in ambulatory

    Directory of Open Access Journals (Sweden)

    Anita Moda Salvadori

    2008-03-01

    Full Text Available O câncer é um grave problema de saúde pública, e, dentre suas variedades, há o câncer de pulmão, que vem crescendo na população brasileira e mundial. A principal causa do câncer de pulmão é o tabagismo. Há três formas de tratamento: cirurgia, radioterapia e quimioterapia; para essa patologia a mais utilizada é a terceira. A enfermeira deve estar apta a lidar com as dificuldades desses pacientes, que durante o tratamento ambulatorial manifestam em seus domicílios efeitos colaterais. Os objetivos desta pesquisa são elaborar um instrumento de coleta de dados para pacientes com câncer de pulmão em quimioterapia ambulatorial e avaliar a validade de seus conteúdos e sua confiabilidade. Teve como guia a teoria do autocuidado de Dorothea Orem. Para sua validação, o instrumento foi primeiramente avaliado por juízes; após isso, foram realizados o pré-teste e o teste de confiabilidade pelo método da equivalência entre observadores. O instrumento se demonstrou confiável, considerando aquilo que se pretendia medir.El cáncer es un grave problema de salud pública y entre sus variedades existe el cáncer de pulmón, que está creciendo en la población brasileña y mundial. La principal causa de cáncer de pulmón es el tabaquismo. Existen tres formas de tratamiento, quirúrgica, por radioterapia y quimioterapia, siendo que para esta patología la más utilizada es la tercera. La enfermera debe estar habilitada para manejar dificultades de los usuarios que ante el tratamiento ambulatorio visiblemente pozo a su domicilio lado efectos. Los objetivos de esta investigación son elaborar un aparato desde colecta de datos para pacientes con cáncer de pulmón en quimioterapia en ambulatorio y evaluar la validad de sus contenidos y su confiabilidad. Tuvo como guía la teoría utilizada del auto-cuidado de Dorothea Orem.Para que sea comprobada la validez de dicho instrumento primeramente este fue evaluado por jueces, luego fue realizado un

  1. Cuidados de enfermería en paciente sometido a quimioterapia intensiva

    OpenAIRE

    Rodríguez Marino, Ignacio

    2017-01-01

    [EN] El cáncer engloba un conjunto de patologías con importante incidencia sobre la población. En la actualidad, la quimioterapia es el tratamiento de elección en muchos casos. Los quimioterápicos no solo actúan sobre las células tumorales, sino también, sobre el conjunto de las células en desarrollo y crecimiento del organismo. Esto supone que los pacientes tratados con quimioterapia presenten efectos secundarios de diversa gravedad, en distintos aparatos y sistemas. La sintomatología adv...

  2. Tratamiento de la leucemia promielocítica con ácido transretinoico y quimioterapia intensiva: Evolución clínica y molecular Treatment of promyelocytic leukemia using transretinoic acid and intensive chemotherapy: Clinical and molecular progress

    Directory of Open Access Journals (Sweden)

    Porfirio Hernández Ramírez

    2002-08-01

    Full Text Available Cuarenta y nueve pacientes con diagnóstico de leucemia promielocítica se trataron con ácido retinoico (45-50 mg/m2/día durante la inducción, después se hizo consolidación con rubidomicina y arabinósido de citosina, seguida de un matenimiento con 6 mercaptopurina y metotrexate durante 2,5 años. Se realizó un estudio evolutivo clínico hematológico y molecular. Cuarenta y tres pacientes lograron remisión completa (88 %; 9 (47 % de 19 enfermos, y 18 (90 % de 20, se encontraban en remisión molecular después de la inducción y la consolidación, respectivamente. La sobrevida global a los 5 años fue de 65 % ± 8 % y la sobrevida libre de evento fue 63 % ± 7 %. La sobrevida libre de enfermedad fue de 71 % ± 7 % en igual períodoForty nine patients diagnosed with promyelocytic leukemia were treated with retinoic acid (45-50 mg/m2/day during induction; afterwards, a consolidation therapy was applied with daunorubicin and arabinosylcitosine, followed by a maintenance therapy with 6 mercaptopurine and methotrexate for 2 years and a half. An evolving clinical, hematological and molecular study was performed. Forty three patients achieved complete remission (88%; 9 (47% of 19 patients and 18(90% of 20 patients had reached molecular remission after induction and consolidation respectively. Global survival rate at 5 years was 65%±8% and event-free survival rate was 63%±7%. Disease-free survival rate was 71%± 7% in the same period

  3. A favor da quimioterapia neoadjuvante à cirurgia no carcinoma pulmonar não de pequenas células (CPNPC** Trabalho em parte apresentado na “1a Jornada Luso-Brasileira de Pneumologia” integrada no “VIII Congrcsso de Pncumologia e Tisiologia do Estado do Rio de Janeiro” (Rio de Janeiro, 4 a 7 de Julho de 2001.

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    Renato Sotto-Mayor

    2001-07-01

    Full Text Available RESUMO: No presente artigo de revisão, o autor aponta os argumentos que justificam a defesa da quimioterapia de indução à cirurgia nos diferentes estádios do carcinoma pulmonar não de pequenas células.REV PORT PNEUMOL 2001; VII (4-5: 333-342 ABSTRACT: In this paper, the author examines data from several studies of induction chemotherapy in addition to surgery for patients with non-small cell lung cancer, and states on its positive role.REV PORT PNEUMOL 2001; VII (4-5: 333-342 Palavras-chavc: quimioterapia, neoadjuvante, cirurgia, carcinoma pulmonar não de pequenas células, Key-words: chemotherapy, neoadjuvant, surgery, non-small cell lung cancer

  4. Adenocarcinoma pulmonar metastásico con evolución favorable al tratamiento con ITK-EGFR en un paciente fumador

    Directory of Open Access Journals (Sweden)

    Joseph Jesús Exebio Jara

    2015-04-01

    Full Text Available Introducción: El cáncer de pulmón es el cáncer con mayor mortalidad en ambos sexos. El esquema de manejo actual del adenocarcinoma pulmonar incluye determinar el estado mutacional del receptor del factor de crecimiento epidérmico (EGFR, por ser la diana para el erlotinib, una terapia biológica. Caso clínico: Varón de 62 años, con hábito tabáquico de alto riesgo oncológico, que debuta con un cuadro de cefalea de un mes de evolución, objetivándose por resonancia magnética tumor cerebral. El diagnóstico inmunohistoquímico post quirúrgico fue adenocarcinoma pulmonar metastásico (TTF-1 (+. La tomografía identificó una lesión en el lóbulo superior derecho del pulmón; no presentaba clínica respiratoria. Al ser positivo para la mutación en el exón 21 del gen EGFR, se inició terapia con erlotinib, siendo bien tolerada por el paciente y manteniendo su estabilidad clínica. El paciente sobrevivió por el lapso de 31 meses posterior a su diagnóstico. Discusión: El tratamiento con erlotinib fue inicialmente indicado en el perfil de una paciente mujer, asiática y no fumadora. La eficacia en los estudios en pacientes con cáncer de pulmón de células no pequeñas evidencia que la sobrevida global es 15,9 meses, muy por debajo del visto en el presente caso.

  5. Cuidados de enfermería en los efectos secundarios de la quimioterapia: Revisión Bibliográfica

    OpenAIRE

    Fernández Fernández, Daniel

    2015-01-01

    El cáncer es un grupo de enfermedades que aparecen con gran frecuencia en la población. Entre las distintas modalidades de tratamiento disponibles, la quimioterapia es una de las que más sintomatología produce en el paciente. El hecho de que la quimioterapia ataque a todas las células en crecimiento, y no sólo a las que se encuentran afectadas por la enfermedad, hace que los efectos secundarios que aparecen afecten a todos los aparatos y sistemas del organismo. Esta gran cantidad de reaccione...

  6. Qualidade de vida relacionada à saúde de pacientes com câncer em quimioterapia

    Directory of Open Access Journals (Sweden)

    Adriana Cristina Nicolussi

    2014-01-01

    Full Text Available Estudio transversal,cuyo objetivo fue evaluar la Calidad de Vida relacionada con la Salud en pacientes con cáncer en quimioterapia, identificar dominios afectados y asociarlos con datos sociodemográficos, clínicos y terapéuticos de la amuestra. Llevado a cado con 152 pacientes entre 2009-2011 en dos centros de quimioterapia, en Ribeirão Preto, SP, Brasil. Se utilizó el instrumento Quality of Life Questionnaire Core-30 . La Calidad de Vida general fue considerada buena, los dominios afectados fueran: función emocional, desarrollo de papel, dolor, fatiga, insomnio y pérdida de apetito. Pacientes del sexo femenino, entre 40-60 años, económicamente activos, con cáncer gástrico, pulmón, neurológico y piel, con metástasis y los pacientes que se sometieron a cirugía y/o radioterapia concomitante presentaran déficit en varias áreas y presencia de más síntomas. El cáncer y su tratamiento afectaran de alguna manera los pacientes, causando déficits en las funciones desarrolladas e más síntomas, perjudicando la Calidad de Vida Relacionada con la Salud.

  7. Morbilidad y mortalidad en una serie de pacientes con neoplasias del peritoneo, tratados con citorreducción peritoneal más quimioterapia hipertérmica intraperitoneal en el Hospital Universitario de la Fundación Santa Fe de Bogotá (ONCOLGroup - estudio ATIA

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    F. Arias

    2012-04-01

    Conclusiones: La cirugía citorreductiva más HIPEC en pacientes bien seleccionados con neoplasias las cuales afectan el peritoneo, resulta un procedimiento que se puede realizar en Colombia con un adecuado perfil de seguridad y eficacia. La mortalidad fue similar a lo reportado en la literatura mundial.

  8. A comunicação com o paciente em cuidados paliativos: valorizando a alegria e o otimismo La comunicación con el paciente EN cuidados paliativos: valorando la alegría y el optimismo Communication with patients in palliative care: favoring cheerfulness and optimism

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    Monica Martins Trovo de Araújo

    2007-12-01

    Full Text Available Este estudo objetivou conhecer as expectativas de pacientes em cuidados paliativos em relação à comunicação com as pessoas da equipe de enfermagem. Os dados foram coletados no primeiro semestre de 2005, por meio de entrevistas semi-estruturadas, junto a 39 pacientes oncológicos sem prognóstico de cura, submetidos à quimioterapia paliativa em uma instituição hospitalar privada da cidade de São Paulo, Brasil. Após transcrição das falas, os dados foram analisados segundo a metodologia de análise do conteúdo. Dos discursos dos entrevistados emergiram quatro categorias. A comunicação interpessoal comprovou ser importante atributo do cuidado paliativo, evidenciando a atenção dada aos sinais não-verbais do profissional para o estabelecimento do vínculo de confiança, a necessidade da presença compassiva, o desejo de não focar a interação e o relacionamento apenas na doença e morte e a valorização da comunicação verbal alegre, que privilegia o otimismo e o bom humor.Este estudio objetivo conocer las expectativas de los pacientes en cuidados paliativos en relación a la comunicación con las personas del equipo de enfermería. Los datos fueron colectados en el primero semestre de 2005, por medio de entrevistas semi-estructuradas, junto a 39 pacientes oncológicos sin pronóstico de cura, sometidos a la quimioterapia paliativa en una institución hospitalario privada de la ciudad de São Paulo, Brasil. Después de la trascripción de las hablas, los datos fueron analizados según la metodología de análisis del contenido. De los discursos de los entrevistados emergieron cuatro categorías. La comunicación interpersonal comprobó ser importante atributo del cuidado paliativo, evidenciando la atención dada a los señales no verbales del profesional para el establecimiento del vínculo de confianza, la necesidad de la presencia compasiva, el deseo de no focalizar la interacción y la relación apenas en la enfermedad y

  9. Tratamiento del cáncer de cabeza y cuello en estadio avanzado inoperable mediante quimioterapia intraarterial y radioterapia concomitante

    OpenAIRE

    García Sevilla, Alba

    2017-01-01

    La quimioterapia intraarterial y radioterapia concomitante fue descrita por Robbins en 1994 en el tratamiento de pacientes con tumores irresecables de cabeza y cuello, consistiendo en una infusión supraselectiva intraarterial de cisplatino en la arteria nutricia del tumor y una infusión sistémica de tiosulfato sódico, un agente quelante que protege al resto del organismo de la toxicidad del cisplatino. Se consigue una dosis alta del quimioterápico en la zona tumoral minimizando los efectos tó...

  10. Manifestações bucais em pacientes submetidos à quimioterapia

    OpenAIRE

    Hespanhol,Fernando Luiz; Tinoco,Eduardo Muniz Barretto; Teixeira,Henrique Guilherme de Castro; Falabella,Márcio Eduardo Vieira; Assis,Neuza Maria de Souza Picorelli

    2010-01-01

    Em decorrência da quimioterapia, alterações na cavidade oral podem ser observadas e levar a complicações sistêmicas importantes, podendo aumentar o tempo de internação hospitalar, os custos do tratamento e afetar diretamente a qualidade de vida dos pacientes. Este trabalho teve como objetivo realizar uma pesquisa em um hospital de oncologia da cidade de Juiz de Fora (MG), sendo realizado através de coleta de dados nos prontuários de pacientes que estiveram em tratamento oncológico, onde foram...

  11. Crianças/adolescentes em quimioterapia ambulatorial: implicações para a enfermagem Niños y adolescentes en quimioterapia ambulatoria: implicaciones para enfermería Children and adolecents in outpatient clinic chemotherapy: nursing implications

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    Juliana Cardeal da Costa

    2002-06-01

    Full Text Available A hospitalização era a indicação mais comum na assistência à criança com câncer, entretanto, um grande enfoque vem sendo dado à desospitalização, viabilizada através do seguimento ambulatorial e/ou assistência domiciliar (home care. O objetivo deste trabalho é analisar as dificuldades que os pais enfrentam no ambiente domiciliar, quando seus filhos são submetidos à quimioterapia ambulatorial. Para tanto, foi realizada uma entrevista semi-estruturada com os pais, nos meses de janeiro e fevereiro de 2000, na sala de quimioterapia do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, da Universidade de São Paulo. Os resultados apontam as seguintes dificuldades: alteração no cotidiano familiar; comunicação ineficiente; alteração da auto-imagem e reação adversa à quimioterapia. Este trabalho possibilitou o acesso a informações de real interesse para assistência à criança/adolescente com câncer e sua família. A partir dos dados empíricos, elaborou-se uma cartilha de orientação para o cuidado domiciliar.La hospitalización todavía es indicación común en el niño con cáncer, aun así, un gran énfasis viene siendo dado a la deshospitalización, conseguida a través del seguimiento ambulatorio, de la quimioterapia ambulatoria, de los hospitales día y la atención domiciliaria (home care. El objetivo de este trabajo es analizar cuales son las dificultades que las familias enfrentan en el ambiente domiciliario cuando sus niños y sus adolescentes son sometidos a la quimioterapia ambulatoria. El lugar de estudio fue la sala de quimioterapia del Hospital Clínicas de la Facultad de Medicina de Ribeirão Preto de la Universidad de São Paulo y la recolección de los datos empíricos fue realizada a partir de una entrevista semi-estructurada con la madre o el padre, en los meses de enero y febrero del 2000. Los resultados muestran las siguientes dificultades: alteración en el cotidiano familiar

  12. Consumo alimentar e estado nutricional de mulheres em quimioterapia

    Directory of Open Access Journals (Sweden)

    Isabela Borges Ferreira

    2016-07-01

    Full Text Available Resumo O objetivo deste estudo foi analisar o consumo alimentar e o estado nutricional de mulheres com câncer de mama (CM em quimioterapia (QT. A avaliação dietética quantitativa foi realizada de acordo com as Dietary Reference Intakes (DRI e a avaliação qualitativa pelo Índice de Qualidade da Dieta Revisado (IQD-R. Dentre o total de pacientes (n = 20, 60% (n = 12 apresentaram circunferência da cintura igual ou superior a 88 cm. Foi verificado 75% (n = 15 de indivíduos com excesso de peso. A média da ingestão de cálcio, cobre, ferro, fibra alimentar, magnésio, potássio, vitamina A, niacina, vitamina B6 e zinco encontrava-se abaixo da recomendação de ingestão adequada e o consumo de vitamina C, fósforo, manganês, sódio e tiamina encontrava-se acima. Quanto à análise do IQD-R, 80% (n = 16 das pacientes apresentaram uma “dieta que requer modificações”, enquanto que 20% (n = 4 apresentaram uma “dieta saudável”. Observou-se elevado excesso de peso, desequilíbrio na ingestão de micronutrientes e dieta que necessita melhorias. Dessa forma, a criação e a utilização de um protocolo de intervenção nutricional são de grande relevância para melhorar a dieta de pacientes com CM que realizam QT.

  13. Ambulatório de quimioterapia pediátrica: a experiência no aquário carioca

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    Isabelle Pimentel Gomes

    2011-01-01

    Full Text Available El objetivo del estudio es relatar la experiencia como enfermera en una quimioterapia pediátrica, decorada para ser atractiva para los niños (Acuario Carioca. Se trata de un estudio de carácter descriptivo con relato de la experiencia vivida en un hospital de la ciudad de Rio de Janeiro,Brazil, entre diciembre de 2007 a mayo de 2008. La decoración del espacio se basó en la película "Buscando a Nemo" (Disney-Pixar®, después de un acuerdo entre la institución y la sociedad civil. El Acuario Carioca llevó la diversión al lugar de tratamiento. Se observó que los profesionales parecían más motivados, se facilitó la atención y las relaciones se han vuelto más dialógicas cuando se utilizan los recursos recreativos, reduciendo la agitación de los niños durante los procedimientos, reducción de náuseas y vómitos, deseo de los niños a permanecer en la sala. El cambio del espacio ofrece actividades estimulantes y divertidas, distracción, calma, seguridad y una mayor aceptación del tratamiento. Así, el niño cambió su enfoque de la enfermedad.

  14. RELATO DE CASO: RESPOSTA COMPLETA COM QUIMIOTERAPIA DE SEGUNDA LINHA EM CÂNCER DE BEXIGA ESTADIO IV

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    Carla Simone Moreira de FREITAS

    2018-04-01

    Full Text Available O câncer de bexiga é a neoplasia mais comum do sistema urinário, sendo raro ocorrer casos de resposta completa a quimioterapia em tumores avançados, quando não realizado cirurgia com intuito curativo. Objetivo: relatar o caso de um paciente que apresentou resposta completa da neoplasia vesical em estadio IV após quimioterapia de 2ª linha. Metodologia: relato de caso. 

  15. [Analysis of the continuity, circulation and productivity of the Revista Española de Quimioterapia].

    Science.gov (United States)

    Gimeno Sieres, E

    2007-06-01

    The primary objective of this study was to compare some of the bibliometric indicators of the continuity, circulation and productivity of the Revista Espanola de Quimioterapia up to 2003 with other spanish journals of Pharmacy and Pharmacology. This was done by reviewing periodicals directories, such as the ISSN (International Standard Serial Number/Número Internacional Normalizado de Publicaciones Seriadas) and ULRICH'S (Periodicals Directory), as well as the CDU (Classification Universal Decimal), national and international databases including IME (Indice Médico Español), ICYT (Indice Espanol de Ciencia y Tecnologia), IPA (International Pharmaceutical Abstracts), SCI Expanded (Science Citation Index Expanded), MEDLINE (Index Medicus), EMBASE (Excerpta Medica), BIOSIS PREVIEWS, ANALYTICAL ABSTRACTS, FSTA (Food Science and Technology Abstracts), SCIFINDER SCHOLAR and CHEMISTRY CITATION INDEX. According to the results, the Revista Española de Quimioterapia, in publication for 15 years, is widely distributed and has a good rating among other scientific journals of the same discipline.

  16. Cateteres venosos centrais totalmente implantáveis para quimioterapia: experiência com 793 pacientes

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    Esmálio Barroso de Oliveira

    Full Text Available OBJETIVO: estudar retrospectivamente os resultados obtidos com a implantação de cateteres totalmente implantáveis em pacientes submetidos à quimioterapia. MÉTODOS: foram colocados 815 cateteres totalmente implantáveis em 793 pacientes submetidos ao regime de quimioterapia preferencialmente utilizando-se a veia cefálica direita. Foram avaliadas as complicações precoces e tardias. RESULTADOS: a análise retrospectiva mostrou duração média dos cateteres de 339 dias. Em 733 (90% cateteres não se observou nenhuma complicação. Entre as complicações precoces observamos um pneumotórax, um mau posicionamento de cateter, uma punção arterial, um sangramento, um hemotórax e hemomediastino e seis hematomas na loja de implantação. Entre as complicações tardias, ocorreram 35 infecções relacionadas ao cateter, dez infecções no sítio cirúrgico, seis obstruções e 20 tromboses. Foram retirados 236 cateteres, 35 devido às complicações e 201 por final de tratamento. CONCLUSÃO: os cateteres totalmente implantáveis para quimioterapia são meios seguros para a administração de substâncias, em vista do baixo número de complicações observadas neste estudo.

  17. Tratamiento conservador en pacientes con retinoblastoma bilateral

    Directory of Open Access Journals (Sweden)

    Juan C. Suárez

    2008-11-01

    Full Text Available OBJETIVO: comparar el tratamiento convencional del retinoblastoma bilateral, usado hasta hace algunos años, consistente en radioterapia o enucleación bilateral, con el tratamiento conservador actual que incluye termoterapia transpupilar (TTT o TTT/quimioterapia al menos en un ojo, en niños con diagnóstico de retinoblastoma bilateral. DISEÑO: estudio retrospectivo descriptivo. MUESTRA: 20 pacientes con diagnóstico de retinoblastoma bilateral que consultaron al Hospital Universitario San Vicente de Paúl, de Medellín, Colombia, entre 1997 y 2007. MÉTODO: se hizo enucleación del ojo con el tumor de mayor tamaño. En el otro ojo se hizo tratamiento con TTT, con el láser diodo (810 nm, spot amplio, solo o combinado con otras terapias. RESULTADOS: se dividió a los pacientes en dos grupos: 16 pacientes (32 ojos en el grupo 1 tratados conservadoramente y 4 pacientes (8 ojos en el grupo 2 con tratamiento convencional. El rango de edad fue de 1-72 meses en el grupo 1 y de 1-12 meses en el grupo 2. El tiempo de seguimiento fue de 7-67 meses para el grupo 1 y de 13-73 meses para el grupo 2. En el grupo 1 se hizo enucleación de 16 ojos (50%, radioterapia externa de uno (3,1%, quimioterapia más termoterapia de 5 (15,6% y quimioterapia más termoterapia más crioterapia de 10 (31,3%. En todos los pacientes se logró preservar al menos un ojo. En el grupo 2, se enuclearon 7 ojos (87,5% y se hizo radioterapia externa más enucleación en un paciente (12.5%. Además, todos los pacientes recibieron quimioterapia. CONCLUSIÓN: la terapia conservadora actual consistente en tratamiento local (termoterapia, crioterapia o braquiterapia y quimiorreducción permite preservar al menos un ojo y en algunos casos de los dos, muchas veces con buena agudeza visual, en niños con retinoblastoma bilateral; se evitan así la enucleación bilateral y la radioterapia externa usada en el tratamiento convencional con todos sus efectos secundarios. La enucleación contin

  18. A favor del Plagio

    OpenAIRE

    Manuel Arranz

    2007-01-01

    Yo no tengo nada contra el plagio. Ustedes, como lectores, seguramente tampoco. Bueno, tal vez prejuicios. Es lógico que los tengan con tanto artículo condenándolo. Hasta ahora, que yo sepa, nadie ha escrito para defenderlo. Los que sí tienen algo, parece ser, son los autores. Una minoría al fin y al cabo. Ya sé que hay que respetar el derecho de las minorías, pero el asunto del plagio, como tantos otros, deberíamos examinarlo con más detalle, y preguntarnos, por ejemplo, ¿por qué se molestan...

  19. Trece tratamientos de la insuficiencia renal aguda secundaria a mieloma múltiple con filtros de high cut off

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    Ana Berni Wennekers

    2016-07-01

    Conclusiones: El tratamiento combinado con quimioterapia más diálisis largas con filtros de HCO resultó eficaz para reducir el nivel de CLLs y recuperar un nivel de función renal suficiente en el 77% de los casos. Con filtros de HCO se consigue un ahorro significativo, en contraposición a lo descrito previamente en la literatura.

  20. Estimulação medular espinhal para tratamento da polineuropatia dolorosa refratária induzida por quimioterapia Estimulación medular espinal para tratamiento de la polineuropatía dolorosa refractaria inducida por quimioterapia Spinal cord stimulation in the treatment of refractory painful polineuropathy induced by chemotherapy

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    José Luciano Braun Filho

    2007-10-01

    Full Text Available JUSTIFICATIVAS E OBJETIVOS: Polineuropatia dolorosa pós-quimioterapia tem sido muitas vezes uma condição refratária ao tratamento clínico conservador. O objetivo deste relato de caso foi mostrar o uso da estimulação medular como técnica alternativa aos métodos convencionais para tratar paciente com quadro doloroso de difícil controle. RELATO DO CASO: Paciente de 72 anos, com polineuropatia dolorosa pós-quimioterapia há mais ou menos dez anos, apresentava dor de forte intensidade (escala analógica visual = 10 em membros inferiores, contínua e diária, apesar do uso de várias medicações específicas para dor neuropática. Foi submetido a implante de eletrodo peridural apresentando melhora significativa das dores (escala analógica visual = 3 e diminuição do uso de medicação. CONCLUSÃO: A estimulação da medula espinhal constitui uma opção terapêutica em pacientes com neuropatia periférica refratária ao tratamento médico convencional quando bem indicada e realizada dentro de critérios estabelecidos.JUSTIFICATIVAS Y OBJETIVOS: La polineuropatía dolorosa posquimioterapia ha sido en muchas ocasiones una condición refractaria al tratamiento clínico conservador. El objetivo de este relato de caso fue mostrar el uso de la estimulación medular como técnica alternativa a los métodos convencionales para tratar paciente con cuadro doloroso de difícil control. RELATO DEL CASO: Paciente de 72 años, con polineuropatía dolorosa pos-quimioterapia hace más o menos 10 años, presentaba dolor de fuerte intensidad (escala analógica visual = 10 en miembros inferiores, continua y diaria, a pesar del uso de varias medicaciones específicas para dolor neuropático. Se sometió a implante de electrodo peridural presentando una mejoría significativa de los dolores (escala analógica visual = 3 y una disminución del uso de medicación. CONCLUSIÓN: La estimulación de la médula espinal constituye una opción terapéutica en

  1. Aplicação da metodologia da assistência a pacientes com Lúpus Eritematoso Sistêmico em pulsoterapia: uma experiência docente Uso de la metodología de la asistencia a pacientes con Lupus Eritematoso Sistémico en quimioterapia por pulso: una experiencia de enseñanza Application of assistance methodology in patients suffering Systemic Erythematosus Lupus in drug pulse therapy: a teaching experience

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    Maria Gorette dos Reis

    2007-04-01

    Full Text Available Este trabalho é um relato de experiência do ensino de Enfermagem Clínica para alunos de graduação, no qual foi utilizada a metodologia de assistência de enfermagem como estratégia de ensino. Aplicada a pessoas adultas, portadoras de Lúpus Eritematoso Sistêmico (LES, em sua maioria mulheres jovens, submetidas a pulsoterapia, uma modalidade terapêutica que, por meio da imunossupressão, reduz o processo inflamatório causado pelos autoanticorpos. Desta forma, a assistência é sistematizada, individualizada e integral e permite ao acadêmico, oportunidades singulares para correlação teórico-prática, com a aplicação de conhecimentos básicos da área de formação, contextualização do processo saúde-doença e focalização ampliada para além do biológico, abrangendo aspectos emocionais, sociais e espirituais e oportunidade para o aluno avaliar as diversas nuanças que interferem nas condições de assistência oferecidas pelos serviços públicos de saúde.Este és un relato de experimento de la enseñanza de Enfermería Clínica para alumnos de graduación, utilizando medología de asistencia de enfermería como habilidad medotológica para acompañar el paciente y enseñar. Empleada a la personas adultas, portadoras de Lúpus Eritematoso Sistémico (LES, en su mayoría mujeres jóvenes, sometidas a la pulsoterapia, una modalidad terapéutica que, por medio de la imunosupresión, reducido el proceso inflamatorio causante por los autoanticuerpos. De esta manera, la asistencia és de sistematización, particular y total, concede al académico, ocasiones raras para correlación teoríca-práctica, con la aplicación del conocimiento básico de la área de formación, contextualización del proceso salud-enfermedad y focalización ampliada para más adelante del biológico, abarcando aspectos emocionales, sociales y espirituales y ocasión para el alumno evaluar las diversas matizes que interponen en las condiciones de asist

  2. A Favor del Plagio

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    Manuel Arranz

    2007-11-01

    Full Text Available Yo no tengo nada contra el plagio. Ustedes, como lectores, seguramente tampoco. Bueno, tal vez prejuicios. Es lógico que los tengan con tanto artículo condenándolo. Hasta ahora, que yo sepa, nadie ha escrito para defenderlo. Los que sí tienen algo, parece ser, son los autores. Una minoría al fin y al cabo. Ya sé que hay que respetar el derecho de las minorías, pero el asunto del plagio, como tantos otros, deberíamos examinarlo con más detalle, y preguntarnos, por ejemplo, ¿por qué se molestan tanto los autores cuando les plagian? ¿En nombre de qué?, sería también una buena pregunta. No me irán a decir a estas alturas que en nombre de la comunidad científica. A fin de cuentas el plagio beneficia la difusión de la ciencia. Los autores se molestan en nombre propio. Naturalmente tienen su derecho, no se lo vamos a discutir, pero, ¿no demuestra eso cierto narcisismo impropio de un científico? ¿La ciencia no es de todos?, como suelen decir en otras ocasiones.

  3. Fatores de risco para trauma vascular durante a quimioterapia antineoplásica: contribuições do emprego do risco relativo Factores de riesgo para el trauma vascular durante la quimioterapia antineoplásica: contribuciones del empleo del riesgo relativo Risk factors for vascular trauma during antineoplastic chemotherapy: contributions of the use of relative risk

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    Cíntia Capucho Rodrigues

    2012-01-01

    Full Text Available OBJETIVO: identificar a relação entre os fatores de risco para trauma vascular e o surgimento de eventos adversos de infiltração ou flebite por quimioterapia antineoplásica. MÉTODOS: Estudo de abordagem quantitativa observacional com 30 mulheres com câncer de mama. RESULTADOS: O tipo de material do cateter apresentou associação que sugere risco (RR=2,76; IC=1,199; 6,369; o fator velocidade de infusão apresentou RR=2,22; entretanto, IC= 0,7672; 6,436; os fatores trajetória, número de punção e mobilidade da veia apresentaram RROBJETIVO: identificar la relación entre los factores de riesgo para el trauma vascular y el surgimiento de eventos adversos de infiltración o flebitis por quimioterapia antineoplásica. MÉTODOS: Estudio de abordaje cuantitativo observacional realizado con 30 mujeres con cáncer de mama. RESULTADOS: El tipo de material del catéter presentó asociación que sugiere riesgo (RR=2,76; IC=1,199; 6,369; el factor velocidad de infusión presentó RR=2,22; mientras que, IC= 0,7672; 6,436; los factores trayectoria, número de punción y movilidad de la vena presentaron RROBJECTIVE: To identify the relationship between risk factors for vascular trauma and the emergence of adverse events of infiltration or phlebitis for antineoplastic chemotherapy. METHODS: A study with a quantitative, observational method with 30 women with breast cancer. RESULTS: The type of catheter material presented an association that suggested risk (RR = 2.76, CI = 1.199, 6.369; the infusion rate factor presented RR = 2.22, however, CI = 0.7672, 6.436; the trajectory factors, number of punctures and vein mobility presented RR <1, but these cannot be considered as protective factors. Insertion site and the visibility of the vein presented a risk close to 1. CONCLUSION: The use of a metal catheter for venipuncture was considered in this study as a factor for Risk for Vascular Trauma. An analysis of the association for the RR showed these results

  4. Cumplimiento con la quimioterapia intravenosa y algunos factores asociados a éste en pacientes oncológicos adultos

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    Mariana Díaz-Amaya

    2013-12-01

    Full Text Available According to literature, the noncompliance rates in cancers chemotherapy are high (10 % - 80 %, which makes this treatment ineffective resulting in a raise of the morbidity, of the mortality and of the health care costs. However, in Colombia there are no studies about it. Objective: To establish the prevalence of compliance with intravenous chemotherapy on adult oncology patients that started and finished the treatment between January of 2011 and January of 2012 in the Hemato-Oncology service of a general hospital. Specifically, we sought to characterize the sample and recognize the associated factors of noncompliance. Sample: 107 cancer patients that met the inclusion criteria. Method: Study with a quantitative approach, non-experimental, cross exploratory. The statistical analysis was done with the program SPSS making an analysis of the central tendency measures, the frequency distribution, and contingency tables applying the chi-square (X2 test and Fisher’s test. Results: The prevalence of noncompliance of chemotherapy was 68 % and the prevalence of compliance was 32 %. Disease stage was found to be an associated factor. Conclusion: Noncompliance has a high prevalence in the studied sample, indicating the importance of bigger scale studies to gain nation-wide information on the prevalence of the phenomenon, as well as the associated factors, to generate proposals of appropriate interventions to the Colombian population considering the role of psychologists in the development and implementation of these strategies and interventions because it should not be forgotten that compliance is a behavioral issue.

  5. A presença de familiares na sala de quimioterapia pediátrica La presencia de miembros de la familia en la sala de quimioterapia pediátrica The presence of family members in the pediatric chemotherapy room

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    Isabelle Pimentel Gomes

    2012-10-01

    Full Text Available Objetivou-se analisar as necessidades do familiar acompanhante na sala de quimioterapia do ponto de vista da criança em tratamento. Estudo qualitativo, realizado em um hospital escola da cidade do Rio de Janeiro, entre abril e junho de 2010. Utilizou-se adaptação da técnica do desenho-estória temático para produção do material empírico junto a sete crianças. A análise foi feita utilizando-se a interpretação temática. As necessidades do familiar para a criança em tratamento são: estímulo para o rodízio entre os membros da família como cuidador da criança; orientação e treinamento para os diferentes membros da família que acompanham as crianças; conforto para o familiar permanecer ao lado da criança; autonomia para o familiar; acolhimento ao irmão saudável; ambiente que proporcione aproximação entre os pais separados para apoiar o filho em tratamento. Torna-se imprescindível a ampliação do foco assistencial restrito à criança com câncer, expandindo a atenção da equipe de enfermagem aos familiares.El objetivo fue analizar las necesidades del familiar acompañante en la sala de quimioterapia desde el punto de vista de los niños en tratamiento. Estudio cualitativo. Se utilizó la técnica de lo diseño estoria con tema para recoletar datos con siete niños con cáncer. El análisis se realizó mediante una interpretación temática. Para los niños las necesidades de la familia son: estímulo a lo intercambio entre los miembros de la familia como los cuidadores del niño; orientación y capacitación para los diferentes miembros de la familia que acompañan a los niños; comodidad para la familia a permanecer con el niño; autonomía de la familia; cuidado de lo hermano sano; medio ambiente proporciona la aproximación entre los padres divorciados. Es esencial ampliar el foco de atención del equipo de enfermería limitada a los niños con cáncer para la familia.The purpose was to analyze the needs of the family

  6. Entrevista motivacional no suporte social de cuidadores de pacientes com câncer de mama em quimioterapia

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    Carla Monique Lopes Mourão

    2017-12-01

    Full Text Available RESUMO Objetivo: Avaliar os efeitos da entrevista motivacional para mudança de comportamento de suporte social junto a cuidadores de pacientes com câncer de mama em quimioterapia. Método: Estudo quase experimental, realizado com mulheres em quimioterapia para câncer de mama e com os cuidadores das respectivas mulheres entrevistadas. A intervenção foi a Entrevista Motivacional Breve, aplicada aos cuidadores indicados pelas pacientes em quatro sessões individuais, com intervalos semanais e duração de 30 minutos cada. O comportamento de suporte social foi avaliado pelas mulheres antes e depois da intervenção pela Escala de Suporte Social. Resultados: Participaram do estudo 18 mulheres e 18 cuidadores. O suporte social das mulheres se mostrou elevado tanto para a dimensão emocional quanto para a instrumental da Escala de Suporte Social, após intervenção utilizada com os cuidadores pela Entrevista Motivacional Breve. Os achados contribuem para a prática clínica de diversas categorias profissionais, na utilização de estratégias de intervenção de baixo custo para melhoria da qualidade de vida durante e após o tratamento de mulheres com câncer de mama. Conclusão: A intervenção utilizada promoveu de forma positiva a mudança comportamental, melhorando o suporte social prestado pelos cuidadores às pacientes com câncer de mama e em realização de quimioterapia.

  7. Tumor germinal mixto con componentes de disgerminoma y coriocarcinoma de ovario en mujer adolescente con ataxiatelangiectasia

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    Eduardo Augusto Gálvez-Cuitiva

    2015-11-01

    días. Se suspendió la quimioterapia porque desarrolló choque séptico que puso en riesgo su vida. Por su enfermedad de base permaneció bajo vigilancia. Actualmente, 17 meses después, la paciente vive sin actividad tumoral.  Conclusión: existe asociación entre ataxia-telangiectasia, leucemia y linfomas. Se describe el caso clínico de una paciente con ataxia-telangiectasia y tumor germinal mixto con componente de disgerminoma y coriocarcinoma de ovario. Se propone establecer un tratamiento especial para estos pacientes inmunocomprometidos, con alto riesgo de cáncer pero, a la vez, de no tolerar los esquemas habituales.

  8. Pautas de protección frente al riesgo de exposición a citostáticos en quimioterapia intraperitoneal hipertérmica

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    Carolina Miraz-Novas

    Full Text Available Objetivo: El objetivo del trabajo realizado es identificar las tareas de riesgo asociadas a la manipulación de citostáticos, detectadas en la aplicación de Quimioterapia Intraperitoneal con Hipertermia (HIPEC aplicada según la técnica de Sugarbaker y las diferentes soluciones llevadas a cabo para su control. Método: La detección y evaluación de los riesgos existentes, así como la propuesta y selección de las diferentes medidas de prevención implantadas se realizaron siguiendo las pautas de: entrevista y estudio de la actividad con el personal especialista implicado, estudio bibliográfico, identificación de requerimientos legales y normativos aplicables, para finalizar estableciendo las medidas de control. Por último se comprobó mediante consulta a las partes involucradas el grado de satisfacción con las medidas adoptadas (adherencia a las medidas y la eficacia de las medidas adoptadas (número de accidentes e incidentes. Resultados: Se identificaron las tareas de mayor riesgo y las principales vías de exposición. Se determinaron medidas de control de la exposición por vía inhalatoria y dérmica, acordes a los requisitos establecidos para la protección de los trabajadores y para uso en campo quirúrgico, minimizando el disconfor que pudieran provocar al personal. Conclusiones: Se pone de manifiesto la posibilidad de conjugar protección del personal, cumplimiento normativo, preservación del campo quirúrgico y confort del personal. A través de acciones formativas e informativas y el trabajo cooperativo de los diferentes servicios participantes, se consiguió un elevado grado de aceptación por parte del personal involucrado de las medidas de prevención establecidas. Se minimizó la inquietud del personal frente a los riesgos laborales afrontados en HIPEC. Como cierre de la acción preventiva, se considera recomendable la comprobación de la eficacia de las medidas adoptadas a través de evaluación cuantitativa.

  9. Lepra histioide con lesiones gigantes de los dedos de manos y pies

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    Gerzaín Rodríguez

    2015-06-01

    La paciente recibió quimioterapia antileprosa (Organización Mundial de la Salud con resultados excelentes. Se concluyó que un infiltrado dérmico difuso con histiocitos fusiformes y algunos vacuolados, que sugiere un tumor fusocelular, cuya inmunohistoquímica sea particularmente rica en células positivas para CD68, debe teñirse con Ziehl-Neelsen, lo que revelará abundantes bacilos si la lesión es de lepra. La adecuada correlación clínico-patológica es necesaria para establecer el diagnóstico y el manejo preciso del paciente.

  10. Quimioterapia adyuvante en el cáncer de pulmón de células no pequeñas Adjuvant chemotherapy for non small cell lung cancer

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    Gustavo Jankilevich

    2009-02-01

    Full Text Available El cáncer de pulmón constituye una de las principales causas de mortalidad en todo el mundo. Su incidencia se relaciona directamente al uso del tabaco. Puede clasificarse a los pacientes en tres grupos: con enfermedad localizada o resecable, con enfermedad localmente avanzada y con enfermedad metastásica. Excepto algunos casos, el primer grupo es pasible de curación. En ellos la cirugía es el tratamiento de elección. El advenimiento de quimioterapia sistémica efectiva, estudios cooperativos bien diseñados y mejor comprensión del comportamiento biológico han logrado mejorar la sobrevida global por primera vez en una centuria. El rol de la quimioterapia adyuvante encuentra un escenario cierto, luego de una década de estudios clínicos. El objetivo de este artículo es realizar una revisión de la evidencia disponible que ha colocado a las combinaciones basadas en cisplatino como el tratamiento de elección luego de la cirugía en los estadios II-IIIA del cáncer de pulmón de células no pequeñas.Lung cancer is one of the leading causes of death worldwide. Its incidence is directly related to tobacco use. The patients can be classified in three large groups: those with localized or resectable disease; those with locally advanced disease and lastly those with metastatic disease. Except for anecdotal cases, in the first group cure is possible. For these patients surgery is the treatment of choice. However, with the appearance of effective systemic chemotherapy, well designed cooperative studies and a better understanding of the biological behaviour, overall survival has improved for the first time in a hundred years. The role of adjuvant chemotherapy is a true option after a decade of clinical trials. The objective of this article is to perform a review of the available evidence which has made cisplatin based combinations is the treatment of choice after surgery for stages II-IIIA non-small cell lung cancer.

  11. Aparición de episodios de neutropenia febril tras la quimioterapia citostática en el paciente oncológico Appearance of febrile neutropenia episodes after cytostatic therapy on Oncology patients

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    Leonardo Lami Casaus

    2009-12-01

    Full Text Available El tratamiento con drogas citotóxicas en el paciente oncológico, tiene como toxicidad limitante de dosis más común la neutropenia y sus complicaciones infecciosas. Su aparición provoca retrasos y reducción de dosis en los ciclos posteriores de quimioterapia, así como deterioro en la calidad de vida de los pacientes. El colectivo de Medicina Oncológica, que incluye el Servicio de Farmacia, decidió realizar un estudio, con el objetivo de analizar la aparición de neutropenia febril tras la administración de la terapia citotóxica y la presencia de otros factores que pueden incrementar el riesgo de estas reacciones. Se estudiaron los 42 pacientes que ingresaron con neutropenia febril tras el tratamiento citotóxico en el periodo comprendido entre febrero y agosto del 2007. Se recogieron variables biomédicas del grupo de pacientes incluidos y se analizó el tratamiento citostático empleado previamente. El grupo de edad que prevaleció fue el de los pacientes mayores de 50 años, con un predomino del sexo masculino y los estadios avanzados con afecciones asociadas. Las localizaciones tumorales más frecuentes radicaron en mama, pulmón y linfoma no Hodgkin. El citostático más señalado en casos de neutropenia febril resultó la adriamicina con un 71,4 %, seguido de la ciclofosfamida con 52,4 %. Los factores que más se asociaron con la aparición de neutropenia febril fueron: quimioterapia con antraciclinas, la edad mayor de 50 años, estadios avanzados y presencia de enfermedades asociadas.Treatment of oncology patient using cytotoxic drugs has the neutropenia and its infectious complications as the commonest dose-limiting toxicity. Its appearance provokes dose delays and reduction during post-chemotherapy cycles, as well as the quality of life deterioration of patients. Oncology Medicine Group including the Pharmacy Service carried out a study to analyze the appearance of febrile neutropenia after cytotoxic therapy administration, and

  12. Opinião de acompanhantes de crianças em quimioterapia ambulatorial sobre uma quimioteca no Município de São Paulo Opinión de acompañantes de niños sometidos a quimioterapia en ambulatorio sobre una quimioteca en el municipio de Sao Paulo Opinion of adults escorting children on an outpatient chemotherapy service about a "Chemo-teca" in a municipality of Sao Paulo

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    Ione Queiroz de Jesus

    2010-04-01

    Full Text Available OBJETIVO: Conhecer a opinião dos acompanhantes de crianças de 2 a 12 anos de idade em tratamento quimioterápico sobre a Quimioteca Fundação Orsa. MÉTODOS: Trata-se de um estudo quantitativo descritivo. Realizaram-se entrevistas semi-estruturadas com 54 acompanhantes de crianças em tratamento quimioterápico ambulatorial. RESULTADOS: Na opinião desses acompanhantes, o ambiente colorido e cheio de brinquedos e a oferta de atividades lúdicas, durante a administração de quimioterápicos, têm influência positiva na qualidade do tratamento e no estado de bem-estar da criança. Apesar da avaliação extremamente positiva sobre o serviço, foram apontados aspectos que necessitam ser aprimorados, principalmente em relação ao atendimento. CONCLUSÃO: Os acompanhantes percebiam que o ambiente e o brincar colaboravam no bem estar das crianças em tratamento. A Quimioteca é uma experiência inovadora que pode servir de exemplo para o desenvolvimento de tecnologias criativas de cuidado às crianças com câncer e suas famílias, contribuindo para a melhoria da assistência a essa clientela.OBJETIVO: Conocer la opinión, de los acompañantes de niños de 2 a 12 años de edad sometidos a tratamiento de quimioterapia, sobre la Quimioteca Fundación Orsa. MÉTODOS: Se trata de un estudio cuantitativo descriptivo. Se realizaron entrevistas semi-estructuradas con 54 acompañantes de niños en tratamiento de quimioterapia en ambulatorio. RESULTADOS: En la opinión de esos acompañantes, el ambiente colorido lleno de juguetes y la oferta de actividades lúdicas, durante la administración de la quimioterapia, tiene influencia positiva en la calidad del tratamiento y en el estado de bienestar del niño. A pesar de la evaluación muy positiva sobre el servicio, fueron apuntados aspectos que necesitan ser mejorados, principalmente en relación a la atención. CONCLUSIÓN: Los acompañantes percibían que el ambiente y el jugar colaboraban en el bienestar

  13. Sarcoma de Kaposi en paciente con SIDA

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    Jesús Ramón León Polanco

    2015-01-01

    Full Text Available Se presenta el caso de un paciente masculino de 33 años de edad, con antecedentes de VIH-SIDA desde hace 10 años, que se mantiene en tratamiento con antirretrovirales. Durante todo este tiempo ha presentado varios episodios de infecciones respiratorias, incluyendo tuberculosis pulmonar 5 años atrás. Acude a consulta refiriendo edemas en miembros inferiores acompañado de lesiones en piel de color violáceo de un año de evolución, previamente interpretado como linfangitis rebelde al tratamiento y que se extendió a la cara interna de los muslos y a los miembros inferiores. Con pérdida de peso, no prurito en las lesiones, fiebre, lesiones en la mucosa oral. Se determinó hemoglobina 89 g/L, leucocitos 4,5 x 109 /L, se estudiaron las funciones hepática y renales resultando normales. Radiografías de tórax y ultrasonido abdominal normales. Se realizó estudio anatomopatológico de piel que informó Sarcoma de Kaposi. Se impuso tratamiento con quimioterapia

  14. Quadro de condicionamento aversivo a situações relacionadas à quimioterapia em paciente com Doença de Hodgkin

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    Marcia Braga Cliquet

    2014-10-01

    Full Text Available Introdução: A doença de Hodgkin é de origem unicêntrica capaz de crescer descontroladamente e disseminar-se através da produção de cópias idênticas das células malignas. Atualmente recomenda-se para tratamento a utilização de terapêutica combinada com ciclos de quimioterapia (QT, cujo esquema standard é o ABVD (doxorrubicina, bleomicina, vinblastina, dacarbazina, associado à radioterapia. Este esquema tem como um de seus efeitos colaterais a ocorrência de náuseas e vômitos que são variáveis para cada paciente, envolvendo, inclusive, aspectos psicológicos. Objetivos: relatar o caso de um paciente que apresentou quadro aversivo às situações associadas à quimioterapia. Metodologia: as informações foram obtidas por meio de revisão do prontuário, entrevista com o paciente, registro fotográfico de exames e revisão da literatura. Relato de caso: Relatamos o caso de um paciente de 43 anos, portador de Linfoma de Hodgkin de Celularidade Mista, estádio IIB, tratado com ABVD por quatro ciclos mais radioterapia. Logo após o primeiro ciclo, o paciente começou a apresentar quadros de aversão às situações associadas à quimioterapia, como cheiros e pessoas que atuavam no setor. Neste, predominava o cheiro de café e cappuccino. Chegou ao extremo de não poder pronunciar tais palavras (cappuccino, quimioterapia, café. O paciente foi encaminhado ao Serviço de Psiquiatria sendo considerado um condicionamento aversivo Pavloviano e tratado com dessensibilização e antidepressivos. Conclusão: Consideramos importante que o ambiente onde é realizada a quimioterapia seja o mais agradável possível a fim de se evitar situações que possam ocasionar este tipo de aversão.

  15. Quimioterapia neoadjuvante em câncer localmente avançado do colo do útero Neoadjuvant chemotherapy in locally advanced cancer of the cervix

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    Eduardo Schünemann Jr

    2002-12-01

    Full Text Available OBJETIVOS: avaliar a quimioterapia neoadjuvante no câncer localmente avançado do colo uterino, por meio da sua aceitabilidade, tolerabilidade, toxicidade, taxa de complicações cirúrgicas, taxa de resposta, taxa de operabilidade e sobrevida em 5 anos. MÉTODOS: foram incluídas 60 mulheres com câncer do colo uterino localmente avançado (IIB e IIIB, submetidas à quimioterapia neoadjuvante com doxorrubicina-bleomicina-cisplatina. Aquelas que se tornaram operáveis após a quimioterapia foram submetidas à cirurgia de Wertheim-Meigs, seguida de radioterapia pélvica complementar. Nas pacientes em que a cirurgia não foi possível após a quimioterapia, realizou-se radioterapia. RESULTADOS: o seguimento médio foi de 108 meses. A taxa de resposta global à quimioterapia foi de 80%, sendo 100% para o estádio IIB e 60% para o estádio IIIB. A porcentagem de pacientes operadas, após a quimioterapia foi de 65%. A sobrevida global em 5 anos para todo o grupo foi 62%. No grupo operado (n=34, a sobrevida global foi de 82,14%, independentemente do estádio inicial. No grupo não operado (n=18, a sobrevida em 5 anos foi 16,67%. CONCLUSÕES: A quimioterapia neoadjuvante com doxorrubicina-bleomicina-cisplatina no câncer do colo uterino localmente avançado é segura, com baixo índice de complicações e permitiu uma alta taxa de operabilidade.PURPOSE: to evaluate neoadjuvant chemotherapy in locally advanced cervical cancer as to its acceptability, tolerability, toxicity, surgical complications, operability, response rate, and overall survival in 5 years. METHODS: sixty women with locally advanced cervical cancer (stages IIB and IIIB, who were submitted to neoadjuvant chemotherapy, were included. All patients were treated with doxorubicin-bleomycin-cisplatin. Those who had a good response, allowing a surgical approach, underwent the Wertheim-Meigs procedure. After surgery, they were submitted to pelvic radiotherapy. Those that could not be submitted

  16. O uso da quimioterapia no tratamento do retinoblastoma: avaliação retrospectiva The use of chemotherapy in the treatment of retinoblastoma: retrospective analysis

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    Fernando Leite Kronbauer

    2000-12-01

    Full Text Available Objetivo:Análise retrospectiva de pacientes com retinoblastoma considerando: 1 - estadiamento e apresentação tumoral à tomografia, 2 - proporção de pacientes com margens comprometidas (nervo óptico no exame anatomopatológico dos olhos enucleados e 3-tratamento com quimioterapia. Métodos: Revisados os prontuários de 11 pacientes consecutivos com diagnóstico de retinoblastoma entre fevereiro/98 e setembro/99, tratados conjuntamente no setor de Oncologia Pediátrica e Serviço de Oftalmologia. Foram selecionados aqueles submetidos à quimioterapia com vincristina, etoposida e carboplatina (VEC num total de 7 pacientes. Foram avaliados: apresentação tumoral (estadiamento, resposta à quimioterapia e sobrevida destes pacientes. Resultados: Os 7 pacientes estudados foram diagnosticados entre 15 e 38 meses de idade (média=25,7 meses, sendo 3 unilaterais, 3 bilaterais e 1 trilateral (pinealoblastoma. Todos pacientes foram tratados com quimioterapia (VEC administrados em 2 a 5 ciclos e divididos em 2 grupos: Grupo 1 - Pacientes tratados com quimioterapia primária visando redução tumoral e preservação de 1 dos olhos (5 pacientes; Grupo 2 - Pacientes tratados com quimioterapia agressiva para doença extra-ocular (2 pacientes. Dos 5 pacientes tratados com quimioterapia primária (4 submetidos a enucleação devido ao grande volume tumoral, 4 obtiveram redução tumoral, 2 responderam apenas inicialmente indo à óbito em 10 meses de média e 1 apresentou-se quimiorresistente. Pacientes com tumor bilateral foram submetidos a radioterapia (EBTR no olho menos acometido. O tempo médio de seguimento após quimioterapia primária foi 12,4 meses. Os dois pacientes submetidos à enucleação e quimioterapia adjuvante, apresentavam metástase cerebral e foram a óbito em média 4/5 meses após início do tratamento. Conclusão: Esse estudo revelou que: 1-os casos de retinoblastoma são diagnosticados tardiamente em nosso meio. 2 - A porcentagem

  17. Manifestações bucais em pacientes submetidos à quimioterapia Buccal manifestations in patients submitted to chemotherapy

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    Fernando Luiz Hespanhol

    2010-06-01

    Full Text Available Em decorrência da quimioterapia, alterações na cavidade oral podem ser observadas e levar a complicações sistêmicas importantes, podendo aumentar o tempo de internação hospitalar, os custos do tratamento e afetar diretamente a qualidade de vida dos pacientes. Este trabalho teve como objetivo realizar uma pesquisa em um hospital de oncologia da cidade de Juiz de Fora (MG, sendo realizado através de coleta de dados nos prontuários de pacientes que estiveram em tratamento oncológico, onde foram avaliadas as prevalências das manifestações orais em relação ao sexo, idade e tipo de tumor. Verificou-se que a mucosite foi a manifestação mais incidente em ambos os sexos em todas as faixas etárias (15,5%. A xerostomia e as demais lesões, como candidíase e lesões aftosas, também estiveram presentes. É possível melhorar a qualidade de vida antes, durante e após as terapias antineoplásicas através de um protocolo de atendimento odontológico que inclua medidas de condicionamento do meio bucal prévia à quimioterapia, como profilaxia, remoção de cáries, tratamento periodontal e de focos periapicais, orientação para higiene oral e dieta, e ainda laserterapia. É importante a inserção do dentista na equipe oncológica para o diagnóstico precoce das manifestações bucais e acompanhamento no período de tratamento.Several changes in the oral cavity due to chemotherapy can be observed and can lead to important systemic complications, increasing the time of the patient in hospital and the costs of the treatment as well as affect the quality of life of the patients. The aim of this study was to assess the oral manifestation in patients treated with chemoterapy according to sex, age and tumor type. Data was collected in an oncology hospital in Juiz de Fora, Minas Gerais State, from patients' records that were submitted to oncologic treatment. It was possible to verify that mucositis, associated or not to other type of lesions

  18. Utilização de experiências musicais como terapia para sintomas de náusea e vômito em quimioterapia

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    Gabriela Jorge Silva

    2014-07-01

    Full Text Available Objetivou-se aplicar as experiências musicais para avaliação dos efeitos terapêuticos em náuseas e vômitos associados à quimioterapia antineoplásica e identificar alterações nos parâmetros vitais dos pacientes que participaram da experiência. Estudo descritivo, transversal, nível II, de abordagem quantitativa, realizado com treze pacientes de um ambulatório de quimioterapia de um hospital particular no município de São Paulo. Foram utilizados dois instrumentos, sendo um deles proposto pela MASCC (Multinational Association on Supportive Care in Cancer. A maior parte da amostra foi composta por pacientes do sexo feminino, com idade entre 40 a 60 anos, casadas e com câncer de mama. Reduziu-se a frequência cardíaca em 77% da amostra; a náusea diminuiu em 100% dos pacientes após a primeira experiência musical, e em 85% após a segunda. Concluiuse ter havido houve redução estatisticamente significativa dos sintomas de náusea e vômito após as experiências musicais.

  19. Utilização de experiências musicais como terapia para sintomas de náusea e vômito em quimioterapia

    Directory of Open Access Journals (Sweden)

    Gabriela Jorge Silva

    Full Text Available Objetivou-se aplicar as experiências musicais para avaliação dos efeitos terapêuticos em náuseas e vômitos associados à quimioterapia antineoplásica e identificar alterações nos parâmetros vitais dos pacientes que participaram da experiência. Estudo descritivo, transversal, nível II, de abordagem quantitativa, realizado com treze pacientes de um ambulatório de quimioterapia de um hospital particular no município de São Paulo. Foram utilizados dois instrumentos, sendo um deles proposto pela MASCC (Multinational Association on Supportive Care in Cancer. A maior parte da amostra foi composta por pacientes do sexo feminino, com idade entre 40 a 60 anos, casadas e com câncer de mama. Reduziu-se a frequência cardíaca em 77% da amostra; a náusea diminuiu em 100% dos pacientes após a primeira experiência musical, e em 85% após a segunda. Concluiuse ter havido houve redução estatisticamente significativa dos sintomas de náusea e vômito após as experiências musicais.

  20. Validação de material informativo a pacientes em tratamento quimioterápico e aos seus familiares Validación del material informativo a los pacientes en tratamiento de quimioterapia y a sus familiares Validation of the informative material for patients and their families undergoing chemotherapeutical treatment

    Directory of Open Access Journals (Sweden)

    Patricia Sanches Salles

    2010-03-01

    Full Text Available O objetivo deste estudo foi a validação do conteúdo e a compreensibilidade do Material informativo a pacientes em tratamento quimioterápico e aos seus familiares. Para avaliar se as informações do material informativo sobre câncer, quimioterapia, cuidados com paciente, alimentação e medicação eram suficientemente esclarecedoras e claras, foram contatados 23 cuidadores principais de crianças com câncer. Os entrevistados responderam a um questionário contendo nove questões fechadas e uma aberta. A avaliação foi positiva e as informações foram consideradas esclarecedoras pela maioria dos participantes, dos quais alguns contribuíram com sugestões, que foram acrescentadas ao material. Após completa finalização, o material servirá como apoio aos pacientes com câncer e aos familiares. O intuito do material é melhorar a qualidade de assistência de enfermagem, pois acredita-se que, quando os responsáveis estão orientados sobre a maneira mais adequada de cuidar, a adesão do paciente ao tratamento aumenta, a informação os torna mais seguros, e colabora-se para o sucesso do tratamento.Refiérase a la validación del contenido y a la comprensibilidad del material informativo a los pacientes en tratamiento de quimioterapia y a sus familiares. Fueron contactados 23 cuidadores que responderán a un instrumento con nueve cuestiones cerradas y una abierta para evaluar si las informaciones del material informativo sobre cáncer, quimioterapia, cuidados con el paciente, alimentación y medicación fueron esclarecedoras, suficientes y claras. La evaluación fue positiva y las informaciones fueron consideradas satisfactorias y esclarecedoras para la mayoría de las personas. Algunas hicieron sugerencias que fueron incluidas en el material. El material informativo pretende ser implantada con el objetivo de mejorar la cualidad de la asistencia de enfermería, pues se cre que cuando los responsables estan orientados sobre la manera m

  1. Avances en el tratamiento de los pacientes con Leucemia Promielocítica Aguda en Recaída

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    A. Sanz Miguel

    2006-04-01

    Full Text Available Hasta la demostración de la actividad sobresaliente del trióxido de arsénico (ATO en recaídas de pacientes con leucemia promielocítica (LPA, el tratamiento de rescate en esta enfermedad consistía en la readministración de ácido holo-trans retinóico (ATRA y quimioterapia para inducir la remisión, generalmente conteniendo citarabina a altas dosis, seguido de consolidación y/o trasplante de progenitores hematopoyéticos (TPH.

  2. Síndrome de lisis tumoral en un paciente con cáncer de riñón tratado con sunitinib

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    Ezequiel Rodríguez-Reimúndes

    2011-04-01

    Full Text Available El síndrome de lisis tumoral (SLT es un trastorno metabólico que ocurre como consecuencia de una destrucción celular masiva. Se caracteriza por la presencia de hiperuricemia, hiperfosfatemia, hipocalcemia e hiperkalemia, y predispone al desarrollo de insuficiencia renal aguda. En la mayoría de los casos el SLT ocurre luego de instaurarse un tratamiento antitumoral y es más frecuente en tumores de alto grado de malignidad y alta sensibilidad a la quimioterapia. Presentamos el caso de un paciente con diagnóstico de cáncer de riñón recidivado que presenta un SLT e insuficiencia renal aguda luego de iniciar tratamiento con sunitinib.

  3. Factors favoring houseplant container infestation with Aedes aegypti larvae in Marília, São Paulo, Brazil Factores que favorecen la infestación de recipientes con plantas domésticas por larvas de Aedes aegypti en Marília, São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    M. L. G. Macoris

    1997-04-01

    -- las macetas y floreros son un hábitat importante de las larvas. Los objetivos de este estudio fueron identificar las macetas y floreros como hábitats de larvas de mosquitos en relación con su número y grado de infestación, los tipos de plantas involucradas y la localización específica de las larvas; investigar los nombres locales de las plantas domésticas y examinar los factores que afectan al cumplimiento de las medidas de control. Los resultados mostraron un promedio de más de cuatro posibles hábitats de larvas relacionados con plantas por cada sitio, de los cuales solo 0,4% tenían el vector. Los recipientes para plantas representaron 31% de todos los receptáculos con larvas de A. aegypti. A pesar de que de una muestra de 126 personas entrevistadas enumeraron 105 nombres de plantas domésticas, 49% de las plantas asociadas con larvas fueron solo de dos tipos: helechos y la planta ornamental Dieffenbachia avoena. La evidente falta de voluntad de la población para aceptar las medidas de control contra A. aegypti en lo que respecta a plantas domésticas parece deberse a la poca frecuencia relativa de A. aegypti en los recipientes domésticos, la falta de confianza en los programas de control como fuente idónea de información sobre plantas y la opinión de que las medidas de control recomendadas son dañinas para las plantas. Actualmente se está planeando una intervención para el control del dengue en la que se usará material educativo que trata específicamente sobre las plantas cuyos recipientes albergan con mayor frecuencia las larvas de A. aegypti. También se hará uso de fuentes de información botánica con mayor credibilidad en materia de plantas. Además, se formulará un plan diferente con un enfoque más atractivo desde el punto de vista de la salud de las plantas para incrementar su posibilidad de aceptación.

  4. Autoras africanas: A favor de las mujeres=African authors: In favor of women

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    Socorro Suárez Lafuente

    2017-06-01

    Full Text Available Resumen: La cultura occidental produce binomios de poder fuertemente inscritos en el lenguaje y el imaginario colectivo. Las subversiones aparecen primero en la zona dominante, como el feminismo, que se extiende, posteriormente, a otros feminismos, igualmente lógicos y reivindicativos, pero con menos capacidad de visibilización en un mundo globalizado. Las mujeres de grupos minorizados que han conseguido acceder a la educación han levantado sus voces y utilizado su potencial creativo a favor de las silenciadas de su cultura, a las que no alcanzaban el feminismo blanco occidental. Amma Darko, Bessie Head y Chimamanda Ngozi Adichie son algunos de los nombres que encabezan un movimiento africano feminista, que prioriza la libertad individual de las mujeres y les hace sentirse orgullosas de ser africanas.   Abstract Western culture produces binaries of power that are deeply inscribed both in language and in the collective imaginarium. Subversions tend to appear in the more affluent class, as is the case with feminism, which later extend to other feminisms, equally important and vindicatory, but with fewer opportunities to become visible within a globalized world. Many women from minoritized groups have had access to education, have been able to use their creative force and have become the voice of many silent women who were not included in the successive waves of Western feminisms. Amma Darko, Bessie Head and Chimamanda Ngozi Adichie are but a few names at the forefront of African feminism, a movement that fights for the individual rights of women and makes them feel proud of their Africanism.

  5. Introducción a las complicaciones graves de la quimioterapia que debe enfrentar un cardiólogo

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    Patricia Avellana

    2007-01-01

    Full Text Available La aplicación de diferentes esquemas farmacológicos para el tratamiento oncológico ha tenido en los últimos años un gran crecimiento, en muchos casos con efectos curativos o claramejoría de la sobrevida y la calidad de vida. Algunos esquemas incluyen drogas que pueden provocar efectos cardiotóxicos graves, lo que motiva la consulta a los cardiólogos que en la mayor parte de los casos no hemos tenido entrenamiento en esta complicación. En estarevisión se resumen mecanismos de acción y efectos adversos de diferentes drogas de uso frecuente en patología oncológica y se exponen casos clínicos con reacciones adversas graves, con dificultades en la toma de decisiones. Finalmente, se discuten los aspectos para tener en cuenta para la prevención, el control y el tratamiento de la cardiotoxicidad por agentes quimioterapéuticos.

  6. Toxicidad del irinotecán en pacientes con cáncer colorrectal y variabilidad del gen UGT1A

    OpenAIRE

    Gayoso Rey, Mónica

    2012-01-01

    El cáncer colorrectal (CCR) ocupa el segundo lugar como causa de mortalidad por cáncer en la mayoría de los países desarrollados. El irinotecán es uno de los fármacos más empleados en la quimioterapia. Sin embargo, existe una variabilidad interindividual en la aparición de efectos adversos. Se han publicado diversos estudios que intentan correlacionar determinados polimorfismos genéticos con la toxicidad, mostrando discrepancias. Pocos de estos trabajos se han centrado en la población español...

  7. Perfil transcricional e resposta à quimioterapia neoadjuvante em câncer de mama Transcriptional profile and response to neoadjuvante chemotherapy in breast cancer

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    Maria Aparecida Azevedo Koike Folgueira

    2011-06-01

    Full Text Available OBJETIVO: Na tentativa de melhorar a acurácia dos modelos preditivos de resposta à quimioterapia neoadjuvante em câncer de mama, utilizou-se a tecnologia de cDNA microarray para determinar o perfil transcricional dos tumores. A avaliação de assinaturas gênicas, associadas à predição de resposta à quimioterapia neoadjuvante, é o objeto desta revisão. MÉTODOS: Foi realizada busca no banco de dados eletrônico http://www.ncbi.nlm.nih.gov/pubmed/, usando as palavras "breast cancer" AND "neoadjuvant/primary chemotherapy" AND "gene expression profile/microarray". Recuperaram-se 279 publicações, excluindo-se as repetições, selecionando-se para exposição aquelas consideradas mais relevantes pelos autores. RESULTADOS: O número de publicações acerca desse assunto vem crescendo ao longo dos anos, chegando a mais de 50 em 2010, abordando resposta a diferentes quimioterápicos como antraciclinas, taxanos, isoladamente ou em associação. Os primeiros estudos são do início da década passada e utilizaram plataformas de microarray produzidas pelos pesquisadores. Trabalhos mais recentes utilizam plataformas de microarray comerciais, cujos dados são depositados em bancos públicos, permitindo análise de um número maior de amostras. Foram identificados vários perfis transcricionais associados à resposta patológica completa. Outros autores utilizaram como desfecho a resposta clínica ao tratamento, determinando, nesse caso, um painel preditivo de resistência ao esquema quimioterápico em questão. Essa questão também é fundamental, pois pode contribuir para individualizar o tratamento, permitindo que pacientes resistentes a determinado agente quimioterápico sejam submetidos a outro esquema terapêutico. CONCLUSÃO: A identificação de pacientes responsivos à quimioterapia é de fundamental interesse e, apesar de passos importantes terem sido dados, o assunto merece estudos adicionais em vista de sua complexidade.OBJECTIVE: To

  8. Aplicación de un modelo pronóstico para predecir la evolución de la neutropenia febril en niños con leucemias agudas A new model applied in prediction of febrile neutropenia in children with acute leukemias

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    Alberto Arencibia Núñez

    2009-08-01

    Full Text Available Se realizó estudio analítico retrospectivo de casos controles en 62 episodios de neutropenia febril presentados por pacientes con hemopatías malignas admitidos en el Instituto de Hematología e Inmunología durante los años 2005 y 2006. Los episodios de neutropenia febril se dividieron en 2 grupos a partir de su evolución favorable (56 % o desfavorable (44 % y se compilaron los parámetros clínicos y de laboratorio en ambos grupos. Los factores que mayor asociación mostraron con la evolución desfavorable fueron la presencia de comorbilidad (sepsis, deshidratación, hipoxia, hipovolemia, mucositis severa, el diagnóstico de leucemia aguda no linfoblástica, el uso de quimioterapia en los 7 días previos al inicio de la fiebre, el compromiso del estado general, y el conteo absoluto de neutrófilos menor de 100 x mm³. Los pacientes con neutropenia febril de evolución desfavorable presentaron entre 3 y 5 factores de riesgo, mientras que los de evolución satisfactoria tuvieron menos de 2 factores de mal pronóstico. El valor predictivo positivo del modelo pronóstico fue del 91,4 % y el negativo del 92,6 %, con una sensibilidad y especificidad del 94,1 % y 89,3 %, respectivamente.A retrospective and analytical control cases study was carried out in 62 episodes of febrile neutropenia present in patients with malignant blood disease admitted in Hematology and Immunology Institute during 2005 and 2006. Above episodes were divided in 2 groups from its favorable course (56% or unfavorable (44% as well as the laboratory and clinical parameters compiled in both groups. Factors with higher association related to unfavorable course were the comorbidities presence (sepsis, dehydration, hypoxia, hypovolemia and severe mucositis, diagnosis of non-lymphoblastic, use of chemotherapy during the 7 previous days to fever onset, general status involvement, and the neutrophil absolute count lower than 100 x mm³. Patients presenting with a unfavorable course

  9. When and why are reliable organizations favored?

    DEFF Research Database (Denmark)

    Ethiraj, Sendil; Yi, Sangyoon

    of the ensuing work examined only corollary implications of this observation. We treat the observation as a research question and ask: when and why are reliable organizations favored by evolutionary forces? Using a simple theoretical model, we direct attention at a minimal set of variables that are implicated...... shocks, reliable organizations can in fact outperform their less reliable counterparts if they can take advantage of the knowledge resident in their historical choices. While these results are counter-intuitive, the caveat is that our results are only an existence proof for our theory rather than...

  10. Neutropenia febril em pacientes com câncer de mama submetidas à quimioterapia: experiência de 12 anos Febrile neutropenia in patients with breast cancer submitted to chemotherapy: a 12 year experience

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    Omero Benedicto Poli Neto

    2004-12-01

    Full Text Available OBJETIVOS: Identificar as características das pacientes com câncer de mama que desenvolveram neutropenia febril, estabelecer fatores de risco para a sua ocorrência e indicadores de evolução desfavorável. MÉTODOS: Realizamos um estudo caso-controle com 65 pacientes. Foram incluídas 13 pacientes que desenvolveram neutropenia febril e quatro controles por caso pareados por data e número de ciclos de quimioterapia prévios, drogas e doses empregadas. Os dados clínicos e laboratoriais foram obtidos dos prontuários médicos. Utilizamos odds ratio (OR e intervalo de confiança (IC de 95% para estimar a significância dos fatores de risco. RESULTADOS: Identificamos dois fatores de risco associados à ocorrência de neutropenia febril: a realização de quimioterapia nas primeiras 24 horas após a cirurgia (OR: 159,9 IC 95%: 9,5 a 2699 e a realização concomitante de quimioterapia e radioterapia da mama (OR: 108,3 IC 95%: 4,9 a 2391. Não observamos diferenças significativas entre casos e controles quanto à idade, índice de massa corporal e contagem de neutrófilos e monócitos antes da quimioterapia. Três pacientes foram a óbito (23,1%. Duas delas tinham idade superior a 60 anos, não apresentavam comorbidades, tinham recebido o primeiro ciclo de CMF nas primeiras 24 horas após a cirurgia e tiveram infecção de sítio cirúrgico. CONCLUSÕES: Os principais fatores de risco associados a neutropenia febril em pacientes com câncer de mama foram quimioterapia nas primeiras 24 horas após a cirurgia, e uso concomitante de quimioterapia e radioterapia da mama. Nosso estudo mostra, portanto, que estas situações devem ser evitadas.PURPOSE: To identify the characteristis of patients with breast cancer who developed febrile neutropenia and to establish risk factors for its incidence and parameters for an unfavorable evolution. PATIENTS AND METHODS: A case-control study was performed and included 65 patients: 13 patients presented febrile

  11. Ansiedade, depressão e qualidade de vida de pacientes com câncer de mama e ginecológico frente aos efeitos da quimioterapia antineoplásica.

    OpenAIRE

    Regino, Patrícia Afonso

    2013-01-01

    Introdução: a avaliação da qualidade de vida (QV) em pacientes com câncer desperta interesse dos pesquisadores devido ao seu impacto nas políticas de saúde. Com novas drogas e seu uso combinado com outros recursos terapêuticos, a quimioterapia é um tratamento sistêmico do doente oncológico, ocasionando os efeitos colaterais, temidos no tratamento. Ansiedade e depressão são consequências que alguns pacientes experimentam, desde o diagnóstico, continuando durante e após o tratamento, aumentando...

  12. Appeals court reverses verdict favoring drug companies.

    Science.gov (United States)

    1995-06-02

    An appeals court reversed a verdict favoring drug companies after the widow of a hemophiliac, whose death was linked to HIV-tainted blood products, sued four pharmaceutical companies to pay damages. The four companies, Alpha Therapeutic Corp., Miles Laboratories Inc., Armour Pharmaceutical Co., and Baxter Travenol Laboratories Inc., provided Factor VIII, a clotting concentrate, to [name removed] [name removed], the plaintiff's husband, from 1972 until his death in 1987. [Name removed]'s wife sued the companies, alleging that the defendants negligently solicited blood plasma from paid donors who had a high risk of having HIV, failed to determine whether any lots of Factor VIII contained plasma from an at-risk donor, failed to warn consumers of possible risks, and failed to heat-treat HIV and other viruses in Factor VIII, despite industry-wide knowledge of the risk of infection. The three-judge panel said the trial judge's decision to avoid ruling on the antigenic stimulation theory, based on insufficient evidence, was improper. In addition, the appeals court said a retrial is necessary because of improper remarks made by Alpha's attorney.

  13. Great Basin geologic framework and uranium favorability

    International Nuclear Information System (INIS)

    Larson, L.T.; Beal, L.H.

    1978-01-01

    Work on this report has been done by a team of seven investigators assisted over the project span by twenty-three undergraduate and graduate students from May 18, 1976 to August 19, 1977. The report is presented in one volume of text, one volume or Folio of Maps, and two volumes of bibliography. The bibliography contains approximately 5300 references on geologic subjects pertinent to the search for uranium in the Great Basin. Volume I of the bibliography lists articles by author alphabetically and Volume II cross-indexes these articles by location and key word. Chapters I through IV of the Text volume and accompanying Folio Map Sets 1, 2, 3, 4, and 5, discuss the relationship of uranium to rock and structural environments which dominate the Great Basin. Chapter 5 and Map Sets 6 and 7 provide a geochemical association/metallogenic grouping of mineral occurrences in the Great Basin along with information on rock types hosting uranium. Chapter VI summarizes the results of a court house claim record search for 'new' claiming areas for uranium, and Chapter VII along with Folio Map Set 8 gives all published geochronological data available through April 1, 1977 on rocks of the Great Basin. Chapter VIII provides an introduction to a computer analysis of characteristics of certain major uranium deposits in crystalline rocks (worldwide) and is offered as a suggestion of what might be done with uranium in all geologic environments. We believe such analysis will assist materially in constructing exploration models. Chapter IX summarizes criteria used and conclusions reached as to the favorability of uranium environments which we believe to exist in the Great Basin and concludes with recommendations for both exploration and future research. A general summary conclusion is that there are several geologic environments within the Great Basin which have considerable potential and that few, if any, have been sufficiently tested

  14. Artroplastía de superficie en cadera. Resultados iniciales favorables en pacientes selectos. [Hip resurfacing arthroplasty: favorable initial results in selected patients

    Directory of Open Access Journals (Sweden)

    Fernando Martín Comba

    2013-12-01

    Full Text Available In­tro­duc­ción El objetivo del presente trabajo es reportar los resultados clínicos y radiológicos iniciales de una serie consecutiva de pacientes selectos tratados en nuestra institución con un único diseño de artroplastia de superficie, comparando además la tasa de revisión temprana con un grupo control de pacientes tratados en el mismo lapso con una artroplastia total de cadera no cementada. Material y ­Métodos Cuarenta y siete pacientes de sexo masculino (49 caderas con diagnóstico de artrosis de cadera que fueron tratados quirúrgicamente con una artroplastia híbrida de superficie, entre noviembre de 2006 y julio de 2009. La edad promedio fue de 44,5 años (rango de 21 a 57. En todos los casos, la indicación de la artroplastia de superficie se realizó en pacientes jóvenes con alta expectativa funcional y siguiendo estrictos criterios de selección radiológicos. Se efectuó un seguimiento clínico y un meticuloso análisis radiológico. Resultados La escala funcional posoperatoria de Merle D’Aubigné-Postel fue, en promedio, de 17,3 puntos a los 43 meses de seguimiento promedio (rango 24-62 meses. El 85% de los pacientes refirió que practicaba alguna actividad deportiva con una escala UCLA promedio de 9,5 (rango 8-10. Un paciente requirió una cirugía de revisión (2,04% por fractura de cuello femoral. No existieron diferencias estadísticamente significativas en cuanto a la tasa de revisión temprana comparando con el grupo control (p = 0,55. Conclusiones En nuestra experiencia inicial con artroplastia de superficie, obtuvimos resultados a corto plazo favorables, en una serie de hombres con artrosis y alta demanda funcional, estrictamente seleccionados.

  15. PULPOTOMIA CON HIDROXIDO DE CALCIO CON MATERIAL DE SELLAJE EN CAVIDADES CURADAS DESPUES DE 2 AÑOS

    OpenAIRE

    Gruythuysen, Rene J.M.; Weerheijm, Karín L.

    2014-01-01

    El hidróxido de calcio entre otros han sido usados por mucho tiempo en la odontología debido a sus propiedades antibacterianas y a su favorable biocompatibilidad cuando se compara con otros agentes antibacteriales. El hidróxido de calcio entre otros han sido usados por mucho tiempo en la odontología debido a sus propiedades antibacterianas y a su favorable biocompatibilidad cuando se compara con otros agentes antibacteriales.

  16. C18. Docetaxel como quimioterapia de 2ª linha nos doentes com CPNPC: estudo prospectivo multicêntrico.

    Directory of Open Access Journals (Sweden)

    A.S. Oliveira

    2003-11-01

    Full Text Available Durante cinco anos (1998-2002 foi realizado um estudo prospectivo com docetaxel (75 mg/m2 d1 3/3 semanas como tratamento de 2ª linha em doentes com CPNPC.Características: sexoM/F:94/15; idade:58.6(33-74; SP£1:96(88%; histologia: adenocarcinoma-52,pavimento-celular-41; estadio IIIB/ IV:19/90. 94% tratados inicialmente com derivados da platina.Administrados 355 ciclos de docetaxel (3.3/doente. RP em 21 doentes (19.3% IC 95% 11.7-26.8 e estabilização em 36(33%. Ausência de correlação entre resultados com quimioterapia de 1ª linha (taxa de resposta/intervalo até progressão e taxa de resposta ao docetaxel.Neutropenia grau ¾: 52 doentes (48%; 4:neutropenia febril; uma morte tóxica. Efeitos adversos não-hematológicos: alopécia (59%, astenia (28% e polineuropatia (22%.Sobrevivência mediana global: 12.7 meses, sobrevivência pósdocetaxel:6.1 meses, tempo até progressão:12 semanas e taxas de sobrevivência 1 e 2 anos:19 e 7%, respectivamente.Resultados positivos apesar de doentes maioritáriamente quimioresistentes ou quimiorefractários(>70% e estadio IV(>80%. Conclui-se que a administração de docetaxel em doentes com CPNPC e SP70% pts were refractory to 1st-line CT and >80% were in stage IV.We conclude that for NSCLC pts with PS<2, docetaxel as a 2nd-line-CT is a worthwile treatment with acceptable toxicity that significantly prolongs survival. Palavras-chave: CPNPC, docetaxel, Key-words: NSCLC, docetaxel

  17. Comparison of the quality of life among persons with lung cancer, before and after the chemotherapy treatment Comparación de la calidad de vida de portadores de cáncer de pulmón antes y después del tratamiento de quimioterapia Comparação da qualidade de vida de portadores de câncer de pulmão antes e após o tratamento quimioterápico

    Directory of Open Access Journals (Sweden)

    Priscila Isolani de Oliveira

    2013-06-01

    Full Text Available OBJECTIVE: this prospective study aimed to assess the quality of life related to health (QLRH of patients with lung cancer after chemotherapy treatment. METHOD: The QLRH was assessed using the questionnaires Quality-of-Life Questionnaire-Core 30 (QLQ-C30 and Lung Cancer Module (LC13, version 3.0. RESULTS: the sample was made up of 11 women and 19 men, with an average age of 68 years (51-87 years. After the chemotherapy treatment, the authors observed a clinically-relevant improvement in general quality of life, as well as in the symptoms of dyspnea, insomnia, hemoptysis, cough, thoracic pain, pain in the arm/shoulder, and financial difficulty. There was a worsening on the functional scale which assesses role performance and symptoms of fatigue, nausea and vomiting, sensory neuropathy, pain in other parts, constipation, loss of appetite and alopecia. CONCLUSION: although the patients have an improvement of their QLRH and symptoms related to the lung cancer after the chemotherapy treatment, there was a worsening of the symptoms which resulted from the toxicity of the chemotherapy medications. OBJETIVO: estudio prospectivo con objetivo de evaluar la calidad de vida relacionada a la salud (CVRS de pacientes con cáncer de pulmón después de tratamiento de quimioterapia. MÉTODO: la CVRS fue evaluada por los cuestionarios Quality-of-Life Questionnaire-Core 30 (QLQ-C30 y Lung Cancer Module (LC13, versión 3.0. RESULTADOS: la muestra estuvo compuesta por 11 mujeres y 19 hombres, con promedio de edad de 68 años (51-87 años. Después del tratamiento de quimioterapia, observamos una mejoría clínicamente relevante de la calidad de vida general, así como en los síntomas de disnea, insomnio, hemoptisis, tos, dolor torácico, dolor en el brazo/hombro y dificultad financiera. Hubo empeoramiento en la escala funcional que evalúa el desempeño de papel y de los síntomas de fatiga, náusea y vómito, neuropatía sensorial, dolor extra

  18. Carcinoma hepatocelular en una paciente con virus de inmunodeficiencia humana/sida y cirrosis hepática

    Directory of Open Access Journals (Sweden)

    Ernesto Arias Beatón

    2015-05-01

    Full Text Available Se presenta el caso clínico de una paciente de 42 años con positividad del virus de inmunodeficiencia humana desde hacía 3 años, quien acudió a la consulta de Cirugía del Hospital Gubernamental de Mbabane, en Swazilandia, por presentar un tumor abdominal doloroso en el cuadrante superior derecho, unido a astenia, anorexia y ligera ictericia. Fue evaluada en la consulta de Oncología y, luego de realizarle los exámenes complementarios necesarios, se le diagnosticó cáncer hepatocelular asociado a virus de inmunodeficiencia humana/sida y cirrosis hepática en estadio III. Posteriormente fue remitida a Sudáfrica para recibir radioterapia y quimioterapia combinadas

  19. 12 CFR 560.110 - Most favored lender usury preemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Most favored lender usury preemption. 560.110... INVESTMENT Lending and Investment Provisions Applicable to all Savings Associations § 560.110 Most favored... permits its most favored lender to charge late fees, then a savings association located in that state may...

  20. 11 CFR 7.20 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Gifts, entertainment, and favors. 7.20 Section... of Special Commission Employees § 7.20 Gifts, entertainment, and favors. Except as provided at 11 CFR... a gift, gratuity, loan, entertainment, or favor for himself or herself, or for another person...

  1. Câncer de mama na gravidez e quimioterapia: revisão sistemática Breast cancer during pregnancy and chemotherapy: a systematic review

    Directory of Open Access Journals (Sweden)

    Denise Leite Maia Monteiro

    2013-04-01

    Full Text Available O objetivo do estudo é estabelecer a segurança do uso da quimioterapia na gestante portadora de câncer de mama e verificar as possíveis intercorrências no feto. Para identificação de publicações foi realizada pesquisa bibliográfica nas bases de dados: MEDLINE/PubMed, LILACS, SciELO, Cochrane, Uptodate e Google acadêmico. A busca totalizou 86 artigos publicados de 2001 a 2012, que foram avaliados por dois revisores obedecendo aos critérios de exclusão e inclusão pré-estabelecidos, sendo selecionados 39 artigos para a elaboração deste estudo. Todos os quimioterápicos utilizados no tratamento do câncer de mama na gravidez pertencem à categoria D, consistindo no uso de 5-fluorouracil (F, doxorrubicina (A ou epirrubicina (E e ciclofosfamida (C ou na combinação de doxorrubicina e ciclofosfamida (AC, método seguro quando utilizado após o primeiro trimestre da gestação. Poucos estudos avaliaram o uso de taxanos (T como docetaxel (D e paclitaxel (P, não sendo demonstrado aumento da ocorrência de malformações fetais e outras complicações maternas quando utilizados no segundo e terceiro trimestres da gestação. O uso do trastuzumabe em gestantes encontra-se associado à oligodramnia e adramnia, não sendo recomendado na gravidez. Em função da quase totalidade dos estudos serem observacionais e retrospectivos, torna-se necessário a confecção de novos estudos prospectivos sobre o tema.This study aimed to establish the safety of chemotherapy use in pregnant women with breast cancer, and to find possible effects in the fetus. A search of MEDLINE/PubMed, LILACS, SciELO, Cochrane, UpToDate, and Google Scholar databases was performed to identify publications, 86 articles published from 2001 to 2012 were retrieved and evaluated by two readers in accordance predetermined exclusion and inclusion criteria; 39 articles were selected. All the chemotherapy drugs used to treat breast cancer during pregnancy belonged to class D, and

  2. Reaching the limits of reciprocity in favor exchange: The effects of generous, stingy, and matched favor giving on social status.

    Science.gov (United States)

    Ouyang, Kan; Xu, Erica; Huang, Xu; Liu, Wu; Tang, Yipeng

    2018-06-01

    Group members gain social status via giving favors to others, but why and when they do so remain unclear in the literature. Building on social exchange theory and social status literature, we identify three types of favor giving among group members (generous, stingy, and matched) and propose that an affective mechanism (i.e., gratitude) and a cognitive mechanism (i.e., perceived competence) underlie the relationship between favor giving and status attainment. Specifically, generous/stingy favor giving has a linear relationship with status attainment through both gratitude and perceived competence, whereas matched favor giving has a curvilinear relationship with status attainment only through perceived competence. An experimental study and a field study lend support to our propositions. Our study complements the literature by offering a complete picture of how three types of favor giving among group members shape their social status in different ways. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  3. Why Koreans are More Likely to Favor "Apology," While Americans are More Likely to Favor "Thank You"

    Science.gov (United States)

    Lee, Hye Eun; Park, Hee Sun

    2011-01-01

    Two studies investigated whether apologies or thanks are preferred in asking favors in the United States and Korea, and how this relates to perceptions of reduction in positive and negative face threats. In the first study (n = 224), participants composed an e-mail message where a favor was asked. In the second (n = 807), participants completed…

  4. Association mapping and favorable QTL alleles for fiber quality traits ...

    Indian Academy of Sciences (India)

    A total of 201 markers were polymorphic and generated 394 ... identified favorable QTL alleles and typical accessions for fiber quality are excellent genetic resources for future cotton .... Field management followed respective local practices.

  5. [Biological and social correlates of favorable and unfavorable neurosis course].

    Science.gov (United States)

    Sarsembaev, K T

    2003-01-01

    Four hundred ninety seven patients with neurosis of Astana (Kazakhstan) community, 116 men and 381 women, have been studied. The patients were traced in 5-year follow up study. Favorable and unfavorable types of the disorder were established, the latter being characterized by transforming into neurotic personality development. The influence of endogenous and environmental factors on neurosis prognosis was examined. To elaborate adequate measures for preventing neurotic personality development, criteria for favorable and unfavorable prognosis of neurotic disorders were suggested.

  6. Efectividad de la quimioterapia adyuvante en carcinoma urotelial infiltrante de vejiga tratado cistectomía radical. Resultados de una política adaptada al riesgo

    OpenAIRE

    Arranz Arija, José Ángel

    2016-01-01

    El cáncer de vejiga es un importante problema de salud por su incidencia, prevalencia, mortalidad y costes económicos que conlleva. En España el cáncer de vejiga se ubicó como el tumor quinto y séptimo de la incidencia de la mortalidad. La patogénesis del cáncer de vejiga parece estar asociada con el contacto de las sustancias cancerígenas con el epitelio de la vejiga, en particular aminas aromáticas. El epitelio que recubre la pelvis renal, uréteres, vejiga y dos tercios proximales de la ure...

  7. Promising reciprocity: When proposing a favor for a request increases compliance even if the favor is not accepted.

    Science.gov (United States)

    Guéguen, Nicolas; Meineri, Sébastien; Ruiz, Clément; Pascual, Alexandre

    2016-01-01

    Research has reported that reciprocity is an important social norm in relationships. In previous studies on reciprocity, participants' behavior was examined after receiving a favor from someone. In a series of field studies, we examined the effect of a statement that proved that a solicitor was someone who respected this principle. Confederates solicited participants for money or a cigarette in exchange for stamps or money, respectively. It was found that the participants complied more readily with the request in the promised favor condition, but most of them refused to take the promised favor. We conclude that individuals were led to help those who respected the putative norm of reciprocity in their social interaction.

  8. Prevención, diagnóstico y tratamiento de la cardiotoxicidad inducida por quimioterapia: ¿qué estamos haciendo?

    Directory of Open Access Journals (Sweden)

    Lázaro de la Cruz Avilés

    2012-09-01

    Full Text Available Las enfermedades del corazón y los tumores malignos constituyen las dos primeras causas de muerte en Cuba, con tasas de mortalidad de 197,5 y 193,6 por 100 000 habitantes, respectivamente, en el año 2011. En Cienfuegos los tumores malignos fueron la primera causa de muerte con una tasa de 115,2 seguida de las enfermedades del corazón con 102,6 por 100 000 habitantes. Las mejoras alcanzadas en la detección y el tratamiento del cáncer han dado origen a una nueva cohorte de pacientes que alcanzan una supervivencia suficiente para que puedan aparecer complicaciones cardíacas derivadas del tratamiento. Lamentablemente, el abundante conocimiento sobre las vías bioquímicas involucradas en el tratamiento dirigido del cáncer no se ha visto acompañado de un conocimiento paralelo de las consecuencias cardíacas de su modulación.

  9. Estudio comparativo del efecto del cepillado con una crema dental con propóleos rojos y de un gel con clorofila

    OpenAIRE

    Estela Gispert Abreu; Elena Cantillo Estrada; Aracelys Rivero López; Berta Oramas Rodríguez

    1998-01-01

    Se analiza comparativamente el efecto de un gel dental de clorofila y de una crema dental con propóleos rojos sobre varios parámetros relacionados con la caries dental, en escolares que se cepillaron durante 21 días con dichos productos. Se obtuvieron resultados favorables principalmente en la disminución del grado de infección por Streptococcus mutans y la elevación de la capacidad individual de remineralización; salvo en este último no hubo diferencias estadísticamente significativas.Author...

  10. Eating competence of elderly Spanish adults is associated with a healthy diet and a favorable cardiovascular disease risk profile.

    OpenAIRE

    Jordi Salas-Salvado; Barbara Lohse; Tricia Psota; Ramon Estruch; Itziar Zazpe; Jose V. Sorli; Merce Serra; Jodi Stotts Krall; Fabiola Ma´rquez; Emilio Ros; PREDIMED Study Investigators

    2010-01-01

    Eating competence of elderly Spanish adults is associated with a healthy diet and a favorable cardiovascular disease risk profile. Eating competence (EC), a bio-psychosocial model for intrapersonal approaches to eating and food-related behaviors, is associated with less weight dissatisfaction, lower BMI, and increased HDL-cholesterol in small U.S. studies, but its relationship to nutrient quality and overall cardiovascular risk have not been examined. Prevención con Dieta Mediterránea (PRE...

  11. Tumor residual pós-quimioterapia neoadjuvante para câncer de mama: impacto sobre o tratamento cirúrgico conservador Residual tumor after neoadjuvant chemotherapy for breast cancer: impact on conservative surgical treatment

    Directory of Open Access Journals (Sweden)

    Edison Mantovani Barbosa

    1999-05-01

    Full Text Available Objetivo: analisar as alterações histopatológicas provocadas pela ação da quimioterapia neoadjuvante (fluoracil, epirrubicina e ciclofosfamida; FEC -- 4 ciclos na área tumoral, no tecido mamário adjacente e nos linfonodos homolaterais, em peças cirúrgicas obtidas de pacientes portadoras de carcinomas primários da mama. Método: estudo histológico detalhado de 30 peças cirúrgicas obtidas por mastectomia radical (Patey de pacientes portadoras de carcinomas primários da mama, previamente submetidas a esse tipo de terapêutica sistêmica. Resultados: observamos regressão tumoral, de grau variável, em todas as peças analisadas. Esta regressão ocorreu de forma irregular, restando inúmeros focos refratários na área ocupada pelo tumor primário. Observamos focos celulares resistentes independentes do tumor primário no tecido mamário. Detalhamos outros achados histopatológicos decorrentes da ação quimioterápica nos tecidos tumoral e mamário, como calcificações e fibrose, e nos linfonodos axilares homolaterais. Conclusão: concluímos que a ação da quimioterapia neoadjuvante não é uniforme, restando focos tumorais refratários, tanto na área do tumor inicial, quanto à distância. A regressão do tumor independe da resposta de regressão dos linfonodos axilares metastáticos. A utilização da cirurgia conservadora pós-quimioterapia neoadjuvante (FEC deve ser evitada.Purpose: analysis of histopathologic alterations caused by neoadjuvant chemotherapy (fluorouracil, epirubicine, cyclophosphamide; FEC - 4 cycles at the tumor site, adjacent mammary tissue and homolateral lymph nodes, as observed in sections of patients with primary breast carcinomas. Method: histological studies performed on 30 surgical sections obtained from radical mastectomy (Patey of patients with primary breast carcinomas, who underwent prior neoadjuvant systemic therapy. Results: all sections showed tumor regression with variable intensity. This

  12. Paciente con esquizofrenia tratado con ziprasidona + clozapina

    Directory of Open Access Journals (Sweden)

    Pol Yanguas E.

    2013-05-01

    Full Text Available P es un paciente diagnosticado de esquizofrenia, sigue en un piso tutelado un programa de rehabilitación, está medicado con clozapina 500 mg/día y ziprasidona 280 mg/ día. Padece hipercolesterolemia, tabaquismo y sus hábitos alimenticios no son buenos. La medicación que utiliza desde 2007 hasta ahora se refleja en la tabla 1. El último tratamiento se le introdujo el 7 de agosto de 2012, habiendo presentado un electro cardiograma (ECG normal, pero con ligera taquicardia ventricular y prolactinemia de 44,8 ng/ml (valores normales: 2-18 ng/ml.

  13. Favorability for uranium in tertiary sedimentary rocks, southwestern Montana

    International Nuclear Information System (INIS)

    Wopat, M.A.; Curry, W.E.; Robins, J.W.; Marjaniemi, D.K.

    1977-10-01

    Tertiary sedimentary rocks in the basins of southwestern Montana were studied to determine their favorability for potential uranium resources. Uranium in the Tertiary sedimentary rocks was probably derived from the Boulder batholith and from silicic volcanic material. The batholith contains numerous uranium occurrences and is the most favorable plutonic source for uranium in the study area. Subjective favorability categories of good, moderate, and poor, based on the number and type of favorable criteria present, were used to classify the rock sequences studied. Rocks judged to have good favorability for uranium deposits are (1) Eocene and Oligocene strata and undifferentiated Tertiary rocks in the western Three Forks basin and (2) Oligocene rocks in the Helena basin. Rocks having moderate favorability consist of (1) Eocene and Oligocene strata in the Jefferson River, Beaverhead River, and lower Ruby River basins, (2) Oligocene rocks in the Townsend and Clarkston basins, (3) Miocene and Pliocene rocks in the Upper Ruby River basin, and (4) all Tertiary sedimentary formations in the eastern Three Forks basin, and in the Grasshopper Creek, Horse Prairie, Medicine Lodge Creek, Big Sheep Creek, Deer Lodge, Big Hole River, and Bull Creek basins. The following have poor favorability: (1) the Beaverhead Conglomerate in the Red Rock and Centennial basins, (2) Eocene and Oligocene rocks in the Upper Ruby River basin, (3) Miocene and Pliocene rocks in the Townsend, Clarkston, Smith River, and Divide Creek basins, (4) Miocene through Pleistocene rocks in the Jefferson River, Beaverhead River, and Lower Ruby River basins, and (5) all Tertiary sedimentary rocks in the Boulder River, Sage Creek, Muddy Creek, Madison River, Flint Creek, Gold Creek, and Bitterroot basins

  14. Efficacy and safety of ior® LeukoCIM (G-CSF in patients with neutropenia after chemotherapy Eficacia y seguridad del ior® LeukoCIM (FEC-G en pacientes con neutropenia posquimioterapia

    Directory of Open Access Journals (Sweden)

    Leslie Pérez Ruiz

    2011-03-01

    efectivos contra los riesgos potenciales de infección. El propósito de este estudio fue evaluar la efectividad y seguridad del LeukoCIM® (CIMAB, La Habana. Se realizó un estudio retrospectivo, observacional con los datos de los pacientes incluidos en el ensayo clínico fase IV abierto, no aleatorizado y multicéntrico. Estos pacientes provenían del Hospital Gustavo Aldereguía Lima y se evaluaron durante un año. Se analizaron los datos demográficos, clínicos y de seguridad. Como profilaxis el fármaco fue administrado de 24-72 h después de la última dosis de quimioterapia y como tratamiento cuando la neutropenia había sido diagnosticada. En ambos casos la dosis única diaria fue de 300 µg por vía subcutánea. La administración del próximo ciclo de quimioterapia en tiempo resultó la variable principal de respuesta y la seguridad del producto se evaluó midiendo los eventos adversos. Se incluyeron 47 pacientes con 95 episodios neutropénicos. El 82,1 % de episodios recibió su próximo ciclo de quimioterapia en tiempo. Los eventos adversos más frecuentes fueron: dolor óseo y fiebre (11,22 % respectivamente, hiperuricemia (9,2 %, leucocitosis y neutrofilia (7,1 % e incremento de LDH (6, 1%. LeukoCIM® resultó efectivo, pues aceleró la recuperación del número de neutrófilos, disminuyó la incidencia de neutropenia febril y permitió administrar las dosis de quimioterapia en tiempo según el protocolo. También se consideró seguro en la serie estudiada, pues solo reportó eventos adversos conocidos.

  15. Cordilleran metamorphic core complexes and their uranium favorability

    International Nuclear Information System (INIS)

    Coney, P.J.; Reynolds, S.J.

    1980-11-01

    The objective of this report is to provide a descriptive body of knowledge on Cordilleran metamorphic core complexes including their lithologic and structural characteristics, their distribution within the Cordillera, and their evolutionary history and tectonic setting. The occurrence of uranium in the context of possibility for uranium concentration is also examined. This volume contains appendices of the following: annotated bibliography of Cordilleran metamorphic core complexes; annotated bibliography of the uranium favorability of Cordilleran metamorphic core complexes; uranium occurrences in the Cordilleran metamorphic core complex belt; and geology, uranium favorability, uranium occurrences and tectonic maps of individual Cordilleran metamorphic core complexes; and locations, lithologic descriptions, petrographic information and analytical data for geochemical samples

  16. Primary lymphoma of the liver treated by extended hepatectomy and chemotherapy: a case report Linfoma primário do fígado tratado por hepatectomia ampliada e quimioterapia: relato de caso

    Directory of Open Access Journals (Sweden)

    Eleazar Chaib

    2002-09-01

    Full Text Available Primary lymphoma of the liver is an extremely rare entity. A case of anaplastic large B-cell (both CD-20 and lambda positive non-Hodgkin's lymphoma that was confined to the liver in a 33-year-old man is reported. The patient was treated with an extended right hepatectomy and combination chemotherapy: cyclophosphamide, adriamycin, vincristine, and prednisone. The patient was disease free 24 months after the procedure.O linfoma primário do fígado é uma entidade extremamente rara. Os autores relatam um caso de linfoma não-Hodgkin de células B grandes anaplásicas (positivo para CD-20 e Lambda em um paciente do sexo masculino de 33 anos. O tumor estava localizado no lobo hepático direito e foi tratado por hepatectomia direita ampliada e quimioterapia pós-operatória com ciclofosfamida, adriamicina, vincristina e prednisone. Vinte quatro meses de seguimento o paciente encontra-se sem recidiva tumoral.

  17. Preschoolers Reduce Inequality While Favoring Individuals with More

    Science.gov (United States)

    Li, Vivian; Spitzer, Brian; Olson, Kristina R.

    2014-01-01

    Inequalities are everywhere, yet little is known about how children respond to people affected by inequalities. This article explores two responses--minimizing inequalities and favoring those who are advantaged by them. In Studies 1a (N = 37) and 1b (N = 38), 4- and 5-year-olds allocated a resource to a disadvantaged recipient, but judged…

  18. 18 CFR 706.202 - Gifts, entertainment, and favors.

    Science.gov (United States)

    2010-04-01

    ... to: (1) Obvious family or personal relationships, such as those between the employee and his parents... EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.202 Gifts, entertainment, and favors. (a) Except as provided in paragraphs (b) and (c) of this section, an employee shall...

  19. Síndrome de lisis tumoral en un paciente con cáncer de riñón tratado con sunitinib Tumor lysis syndrome in a patient with a renal carcinoma treated with sunitinib

    Directory of Open Access Journals (Sweden)

    Ezequiel Rodríguez-Reimúndes

    2011-04-01

    Full Text Available El síndrome de lisis tumoral (SLT es un trastorno metabólico que ocurre como consecuencia de una destrucción celular masiva. Se caracteriza por la presencia de hiperuricemia, hiperfosfatemia, hipocalcemia e hiperkalemia, y predispone al desarrollo de insuficiencia renal aguda. En la mayoría de los casos el SLT ocurre luego de instaurarse un tratamiento antitumoral y es más frecuente en tumores de alto grado de malignidad y alta sensibilidad a la quimioterapia. Presentamos el caso de un paciente con diagnóstico de cáncer de riñón recidivado que presenta un SLT e insuficiencia renal aguda luego de iniciar tratamiento con sunitinib.The tumor mor lysis syndrome (TLS is a metabolic disorder resulting from a massive tumor breakdown. It is characterized by hyperuricemia, hyperphosphatemia, hypocalcemia and hyperkalemia and predisposes to acute renal failure. TLS usually occurs after the initiation of cytotoxic therapy and is more frequent in the case of neoplasias with a high proliferative rate or that are highly chemo-sensitive. We report the case of a man with a recurrent kidney cancer who presented with a TLS and acute renal failure after initiation of sunitinib.

  20. Actitud de universitarios hacia las personas con discapacidad

    Directory of Open Access Journals (Sweden)

    Alexis Araya-Cortés

    2014-08-01

    Full Text Available El objetivo de este estudio fue describir y comparar la actitud hacia las personas con discapacidad de estudiantes de pedagogía, con estudiantes de otras profesiones y en distintos niveles de formación. Se utilizó un diseño descriptivo y correlacional en el que participaron 260 estudiantes de ambos sexos de una universidad privada de la cuidad de La Serena, Chile. Como instrumento se aplicó la Escala de Actitudes hacia las Personas con Discapacidad de Verdugo, Jenaro y Arias. Los resultados mostraron que la totalidad del alumnado presenta actitudes positivas. En relación con el tipo de carrera y nivel de estudio no se encontraron diferencias estadísticamente significativas. Se puede inferir que los estudiantes presentan una predisposición favorable a comportarse de manera efectiva frente a personas con discapacidad, valorando positivamente sus capacidades y reconociendo sus derechos fundamentales.

  1. Videojuego con Realidad Virtual

    OpenAIRE

    González Mora, César

    2017-01-01

    El objetivo del proyecto es el desarrollo de un videojuego deportivo que utilice realidad mixta. El videojuego se podrá utilizar con dispositivos de tipo cardboard, y utilizará realidad aumentada para la interacción del jugador con el videojuego. En el desarrollo se utilizará el motor Unity para conseguir una aplicación multiplataforma, y la librería Vuforia para implementar realidad mixta.

  2. Sistemas integrados con Arduino

    OpenAIRE

    EL YAKOUTI, MOHAMMED

    2017-01-01

    Design of a robot prototype remotely controllable from Bluetooth using Arduino. Control and testing of sensors and events interacting with Arduino and Bluetooth. Diseño de un prototipo de robot controlable remotamente con Bluetooth utilizando Arduino. Control y verificación de los sensores y eventos que interactúan mediante el Arduino y el Bluetooth. El Yakouti, M. (2017). Sistemas integrados con Arduino. http://hdl.handle.net/10251/89274. TFGM

  3. Investigando con personas con dificultades de aprendizaje

    Directory of Open Access Journals (Sweden)

    Borja González Luna

    2013-12-01

    Full Text Available El artículo muestra los orígenes de lo que Walmsley (2008 denomina «investigación inclusiva». Para comprender qué se entiende por investigación inclusiva tenemos que remontarnos a los debates epistemológicos sobre las metodologías cuantitativas y cualitativas, acontecidos en la década de los 90, en torno a la revista Disability & Society. A partir de una síntesis de dichos debates, focalizados en el ámbito de la «discapacidad intelectual y del desarrollo», se exponen dos estrategias de colaboración con dicha población: a una aproximación etnográfica (de trabajo grupal, y b una aproximación biográfica (de trabajo individual. A continuación se esboza un posible diseño de trabajo de campo que intenta superar el paradigma cualitativo «clásico» con el objetivo de incluir a dicho colectivo más allá del rol de «sujetos de la investigación». Para finalizar se recoge el debate sobre la accesibilidad de los resultados de la investigación a los participantes en dichas investigaciones, y con ello la necesaria innovación en el ámbito de las «devoluciones» de los resultados, cuando se trata de incluir a personas que presentan limitaciones para la comprensión del lenguaje abstracto oral y/o escrito.

  4. Design integration of favorable geometry, structural support and containment

    International Nuclear Information System (INIS)

    Purcell, J.A.; McGehee, G.A.

    1991-07-01

    In designs for fissile processes at Savannah River site, different approaches have been used to provide engineered margins of safety for criticality with containment and seismic resistance as additional requirements. These requirements are frequently at odds in engineered systems. This paper proposes a plan to take advantage of vessels with favorable geometry to provide seismic resistance and to support a glovebox for containment. Thin slab tanks, small diameter pencil tanks, annular tanks, and other novel designs have been used for criticality safety. The requirement for DBE seismic resistance and rigid control of dimensions leads the designer to consider annular tanks for meeting these requirements. The high strength of annular tanks may logically be used to support secondary containment. Hands-on access to all instruments, piping etc. within containment can be provided through gloveports, thus a specialized glovebox. This paper examines the advantages of using an annular tank design to provide favorable geometry, structural support and containment

  5. Uranium favorability of southwestern Oklahoma and north-central Texas

    International Nuclear Information System (INIS)

    Stanton, G.D.; Brogdon, L.D.; Quick, J.V.; Thomas, N.G.; Martin, T.S.

    1977-10-01

    Results are presented of a project to identify and delineate units and (or) facies that are favorable for uranium in the Upper Pennsylvanian and Lower Permian strata of north-central Texas and southwestern Oklahoma. To aid in this evaluation, an assessment of the probable uranium rocks (Wichita and Arbuckle Mountains) was necessary. Surface samples were collected from igneous and sedimentary rocks. Stream-sediment samples were also collected. However, the main emphasis of the investigation of the sedimentary units was on the identification of sedimentary facies trends in the subsurface and an evaluation of the uranium favorability within units studied. The area investigated centers along the Red River, the boundary between Texas and Oklahoma. The project area encompasses approximately 17,000 sq. mi. It includes all or parts of Cooke, Montague, Clay, Wichita, Wilbarger, Hardeman, Baylor, Knox, and Archer Counties in Texas and Love, Jefferson, Cotton, Tillman, Jackson, Stephens, Carter, Comanche, Harmon, and Greer Counties in Oklahoma

  6. A significant shift in favor of nuclear energy since 2005

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    A new opinion poll shows a general trend in Europe in favor of nuclear energy: 44% of the people interrogated are for nuclear energy while only 37% were for in 2005. About 40% of the people against nuclear energy would change their mind if a safe and definitive solution for the management of radioactive waste was found. The survey also shows that more people are aware of the assets of nuclear energy in terms of energy independence and greenhouse gas emission. The countries where the support is the strongest are the Czech Republic (64%), Lithuania (64%), Sweden (62%) and Finland (61%). In France, the biggest nuclear energy producer in Europe, the rate of favorable opinion for nuclear energy remains constant at 52%. (A.C.)

  7. Sintomatología depresiva y calidad de vida en pacientes mujeres con cáncer de mama

    Directory of Open Access Journals (Sweden)

    Rubén Valle

    2006-10-01

    Full Text Available Introducción: Las pacientes con cáncer de mama tienden a desarrollar algún tipo de trastorno psiquiátrico, principalmente depresión. Una manera de evaluar cómo las pacientes conllevan su enfermedad es a través de la calidad de vida. Objetivos: Determinar la prevalencia de sintomatología depresiva y calidad de vida y sus asociaciones con el tiempo desde el diagnóstico y el estado menopáusico. Diseño: Estudio analítico, observacional y transversal. Lugar: Servicio de Oncología del Hospital Arzobispo Loayza. Participantes: Mujeres con diagnóstico clínico e histológico de cáncer de mama que acudieron para tratamiento con quimioterapia. Intervenciones: Se utilizó el inventario de depresión de Beck, la escala de calidad de vida de Mezzich y Cohen y un cuestionario demográfico. El análisis fue realizado con la prueba exacta de Fisher, t de student y regresión lineal. Principales medidas de resultados: Sintomatología depresiva, calidad de vida. Resultados: Se encuestó 24 pacientes, encontrándose una prevalencia de 38% de sintomatología depresiva y 38% de baja calidad de vida. No se halló asociación significativa de sintomatología depresiva y nivel de calidad de vida con alguno de los factores asociados, excepto en la relación de este último con el grado de instrucción de la paciente, con un OR de 11,2 (p= 0,047, IC 95% 0,99 a 125,6. Conclusiones: Se encontró una prevalencia de 38% de sintomatología depresiva y 38% de baja calidad de vida. El tiempo desde el diagnóstico y estado menopáusico no tuvieron una asociación significativa con la sintomatología depresiva y la calidad de vida. El único factor asociado significativamente con la calidad de vida fue el grado de instrucción.

  8. Menor valor: ¿oferta más favorable?

    Directory of Open Access Journals (Sweden)

    Iván Alirio Ramírez Rusinque

    2014-07-01

    Full Text Available La más importante transformación establecida por la Ley 1150 de 2007 en la contratación estatal radicó en la determinación del menor valor como la oferta más favorable para las entidades estatales, cuando se trate de la adquisición o suministro de bienes y servicios de características técnicas uniformes y de común utilización. Por ello, reviste de gran importancia realizar un análisis desde el punto de vista jurídico y normativo, que permita establecer si la mutación sufrida al concepto de oferta más favorable trajo consigo los fines perseguidos por la reforma, o en su defecto fue perjudicial la solución, al afectar el deber de selección objetiva, los principios de la contratación estatal de igualdad, eficacia, transparencia, planeación y equilibrio financiero del contrato y el principio constitucional de la libre competencia. Para de esta forma establecer si el modelo del menor valor como criterio de la oferta más favorable resulta eficiente jurídicamente en el campo de la contratación estatal, y si las reglas establecidas en la actualidad permiten el desarrollo armónico del sistema establecido por la Ley 1150 de 2007.

  9. Evolution favors protein mutational robustness in sufficiently large populations

    Directory of Open Access Journals (Sweden)

    Venturelli Ophelia S

    2007-07-01

    Full Text Available Abstract Background An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution. Functionally similar proteins can differ substantially in their robustness to mutations and capacity to evolve new functions, but it has remained unclear whether any of these differences might be due to evolutionary selection for these properties. Results Here we use laboratory experiments to demonstrate that evolution favors protein mutational robustness if the evolving population is sufficiently large. We neutrally evolve cytochrome P450 proteins under identical selection pressures and mutation rates in populations of different sizes, and show that proteins from the larger and thus more polymorphic population tend towards higher mutational robustness. Proteins from the larger population also evolve greater stability, a biophysical property that is known to enhance both mutational robustness and evolvability. The excess mutational robustness and stability is well described by mathematical theory, and can be quantitatively related to the way that the proteins occupy their neutral network. Conclusion Our work is the first experimental demonstration of the general tendency of evolution to favor mutational robustness and protein stability in highly polymorphic populations. We suggest that this phenomenon could contribute to the mutational robustness and evolvability of viruses and bacteria that exist in large populations.

  10. SECADO DE UCHUVA (Physalis peruviana L) POR AIRE CALIENTE CON PRETRATAMIENTO DE OSMODESHIDRATACIÓN

    OpenAIRE

    CASTRO, Adriana M; RODRÍGUEZ, Ligia; VARGAS, Edgar M

    2008-01-01

    En este trabajo se determinan las condiciones de temperatura más favorables para un proceso de secado de uchuva (Physalis peruviana L) con aire caliente, con deshidratación osmótica (DO) como pretratamiento, utilizando una solución de sacarosa de 70o Brix a 40oC durante 16 horas. Se realiza un seguimiento de la degradación de β-caroteno con el tiempo y la temperatura. En la fruta tratada con aire caliente a 60oC y pretratada con DO, se obtiene una pérdida total de β-caroteno del 98%. La fruta...

  11. Sentinel lymph node biopsy in patients with locally advanced breast cancer after neoadjuvant chemotherapy Biopsia do linfonodo sentinela em câncer na mama localmente avançado pós-quimioterapia neoadjuvante

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Walter Aguiar

    2012-12-01

    Full Text Available PURPOSE: To check the rate of sentinel lymph node (SLN identification in patients with locally advanced breast cancer who underwent neoadjuvant chemotherapy comparing intraoperative contact cytology (imprint and embedded in paraffin and validation of methods. METHODS: A cross-sectional validation of diagnostic test involving 34 patients from the outpatient clinic of the Maternity School Assis Chateaubriand. The patients had locally advanced breast cancer and were treated with neoadjuvant chemotherapy. Those with clinically negative axilla underwent SLN biopsy, studied by imprint and histopathology in paraffin. All patients underwent axillary dissection and its histopathological study. RESULTS: The SLN identification rate was 85.3% (29/34. The sensitivity of imprint associated with paraffin on detection of metastasis compared to histopathology of the axillary content was 84.62% and specificity of 100% with false-negative rate of 12.01% and an accuracy of 92.77%. CONCLUSION: The search for metastases in the SLN by imprint and histopathological analysis in paraffin compared to the gold standard (axillary dissection had a low sensitivity with high rate of false negatives in our sample.OBJETIVO: Verificar a taxa de identificação do linfonodo sentinela (LS em pacientes portadoras de câncer na mama localmente avançado e que foram submetidos à quimioterapia neoadjuvante comparando a citologia de contato intraoperatória (imprint e a inclusão em parafina e validação dos procedimentos. MÉTODOS: Estudo transversal de validação de teste diagnóstico envolvendo 34 pacientes oriundas do Ambulatório da Maternidade-Escola Assis Chateaubriand. As pacientes eram portadoras de câncer na mama localmente avançado e foram tratadas com quimioterapia neoadjuvante. Àquelas com axila clinicamente negativa foram submetidas à biopsia do LS, esse estudado por impint e histopatologia em parafina. Todas as pacientes foram submetidas a esvaziamento axilar e seu

  12. Recentes avanços da quimioterapia das leishmanioses: moléculas intracelulares como alvo de fármacos Recent advances on leishmaniasis chemotherapy: intracelular molecules as a drug target

    Directory of Open Access Journals (Sweden)

    Rômulo José Soares-Bezerra

    2004-06-01

    Full Text Available Leishmanioses são doenças causadas por protozoários do gênero Leishmania sp., que se apresentam na forma promastigota ou amastigota; os promastigotas infectam o inseto vetor e os amastigotas são as formas infectivas antes presentes em macrófagos humanos. O tratamento utilizado pela clínica tem se mostrado ineficaz; os fármacos utilizados se apresentam na forma injetável, o que dificulta o tratamento, já que o paciente, para ser tratado, deve ser internado para as aplicações - que são dolorosas - e assim muitos pacientes desistem do tratamento. Outra razão para a internação é a monitoração dos efeitos colaterais causados pelos fármacos. Por estas razões a quimioterapia para leishmaniose tem sido objeto de estudo de muitos laboratórios de pesquisa, os quais têm testado outras substâncias químicas e extratos de plantas com a finalidade de se encontrar novos agentes leishmanicidas com menores efeitos colaterais e ótima biodisponibilidade. Além disso, pesquisam-se, também, outras formas farmacêuticas que viabilizem a aplicação desses fármacos, o que tornaria desnecessária a internação do paciente para se efetuar o tratamento. Este artigo visa discutir os recentes avanços da quimioterapia utilizada para as leishmanioses e, também, apresentar os aspectos farmacológicos e bioquímicos da participação de moléculas intracelulares do parasita como alvos de fármacos.The leishmaniases are diseases caused by protozoan parasites Leishmania sp., that are present in promastigotes or amastigotes forms; the promastigotes infect the sand fly vector, and the amastigotes are the infective forms presented on human macrophages. These protozooses showed two types of clinical manifestations: tegumentar and visceral. The clinical treatments used have shown inefficient; the drugs utilized are presented in injectable form, difficulting the treatment, since to be the patient, may be interned for applications, which are painful

  13. Deglutição após quimioterapia e radioterapia simultânea para carcinomas de laringe e hipofaringe Swallowing after chemotherapy and radiotherapy for laryngeal and hypopharyngeal carcinomas

    Directory of Open Access Journals (Sweden)

    Andréa Bizarria Cintra

    2005-04-01

    Full Text Available OBJETIVO: Avaliar a deglutição orofaríngea de pacientes submetidos a protocolo de preservação de laringe no Hospital do Câncer AC Camargo. MÉTODOS: De 43 pacientes com carcinoma epidermóide de laringe e hipofaringe tratados com quimioterapia semanal (paclitaxel 30 mg/m² e cisplatina 20 mg/m² concomitante à radioterapia externa fracionada (180 cGy/dia, dose total 7040 cGy, foram avaliados 31 pacientes. A avaliação consistiu de videofluoroscopia. Os resultados foram classificados de acordo com alterações de motilidade orofaríngea, estases, aspiração e severidade da disfagia. RESULTADOS: alterações de fase preparatória e oral: estase em cavidade oral (58% e aumento do tempo de trânsito oral (32,3%; fase faríngea: estase em valécula (83,9%, redução da elevação laríngea (74,2%, atraso no início da deglutição faríngea (51,6% e estase em hipofaringe (45,2%. A deglutição funcional foi observada em 35,5% dos pacientes, 54,8% tinham disfagias discretas ou moderadas e 9,6% disfagias severas. CONCLUSÃO: A associação de quimioterapia e radioterapia para preservação laríngea resulta em alterações da deglutição, na maior parte discretas a moderadas. Alguns pacientes, entretanto, evoluem com disfagia severa, em que a alimentação por via oral não é possível.The main goals of the larynx preservation protocol are eradication of cancer and preservation of a functional larynx with maintenance of respiration, phonation and swallowing. Few studies, however have addressed functional outcomes. OBJECTIVE: Functional evaluation of oropharyngeal swallowing in patients enrolled in a larynx preservation protocol at the Hospital do Câncer AC Camargo. METHODS: Evaluation of swallowing was performed by videofluoroscopy in 31 patients, focusing on: oropharyngeal motility disorders, stasis, laryngeal penetration, aspiration and severity of dysphagia. RESULTS: Swallowing analysis: 5 patients showed inefficient bolus preparation

  14. Miliaria-rash after neutropenic fever and induction chemotherapy for acute myelogenous leukemia Miliária 'rash' após neutropenia febril e quimioterapia de indução para a leucemia mielóide aguda

    Directory of Open Access Journals (Sweden)

    Tuyet A Nguyen

    2011-08-01

    Full Text Available Miliaria is a disorder of the eccrine sweat glands which occurs in conditions of increased heat and humidity. It can be associated with persistent febrile states as well as with certain drugs. We presented a 40 year-old female with myelodysplastic syndrome and progression to acute myelogenous leukemia who was admitted to the hospital for chemotherapy induction. The patient was treated with idarubicin and cytarabine. She became pancytopenic and developed neutropenic fever and was started on vancomycin and cefepime, but was persistently febrile with night sweats. Five days into her fevers, she developed diffuse, nonpruritic and fragile vesicles together with drenching nightsweats. The patient's exanthem was diagnosed as Miliaria crystallina, most probably induced by neutropenic fever and idarubucin exposureMiliária é uma desordem das glândulas sudoríparas écrinas, que ocorre em condições de aumento de calor e umidade. Miliária pode ser associada com estados febris persistentes bem como com certos medicamentos. Apresentamos o caso de uma mulher de 40 anos com síndrome mielodisplásica e progressão para leucemia mielóide aguda que foi admitida no hospital para quimioterapia de indução. A paciente foi tratada com idarrubicina e citarabina. Ela se tornou pancitopênica e desenvolveu neutropenia febril. Iniciou tratamento com vancomicina e cefepime, mas a febre com sudorese noturna continou. Cinco dias depois a paciente desenvolveu vesículas difusas, não pruríticas e frágeis juntamente com a persistência de sudorese noturna. O exantema do paciente foi diagnosticado como Miliária cristalina, provavelmente induzida por neutropenia febril e exposição a idarubucin

  15. Catalytically favorable surface patterns in Pt-Au nanoclusters

    KAUST Repository

    Mokkath, Junais Habeeb

    2013-01-01

    Motivated by recent experimental demonstrations of novel PtAu nanoparticles with highly enhanced catalytic properties, we present a systematic theoretical study that explores principal catalytic indicators as a function of the particle size and composition. We find that Pt electronic states in the vicinity of the Fermi level combined with a modified electron distribution in the nanoparticle due to Pt-to-Au charge transfer are the origin of the outstanding catalytic properties. From our model we deduce the catalytically favorable surface patterns that induce ensemble and ligand effects. © The Royal Society of Chemistry 2013.

  16. More evidence in favor of light dark matter particles?

    International Nuclear Information System (INIS)

    Boehm, Celine; Ascasibar, Yago

    2004-01-01

    In a previous work, it was found that the light dark matter scenario could be a possible explanation to the 511 keV emission line detected at the center of our galaxy. Here, we show that hints of this scenario may also have been discovered in particle physics experiments. This could explain the discrepancy between the measurement of the fine structure constant and the value referenced in the CODATA. Finally, our results indicate that some of the light dark matter features could be tested in accelerators. Their discovery might favor N=2 supersymmetry

  17. Giochiamo con i robot

    Directory of Open Access Journals (Sweden)

    Andrea Bonarini

    2009-01-01

    Full Text Available "Giochiamo con i robot" e' un laboratorio interattivo per grandi e piccini realizzato per l'edizione 2007 del Festival della Scienza di Genova. Lungo un percorso che va dalla telerobotica alla robotica evolutiva, il laboratorio sviluppa il tema di dare intelligenza ai robot. Questo percorso, le cui tappe sono le varie installazioni, si conclude nella "bottega" dove e' possibile costruire e programmare i propri robot o smontare e modificare quelli esposti durante il percorso didattico. I visitatori sono coinvolti in attivita' ludiche grazie alle quali possonoentrare in contatto con alcune delle idee potenti della robotica,

  18. disegnare con ... Alberto Pratelli

    Directory of Open Access Journals (Sweden)

    Roberto Mingucci

    2017-12-01

    Full Text Available Con questa breve intervista ad Alberto Pratelli, (non a caso scelto per aprire questa nuova rubrica intendia-mo inaugurare un dialogo con personalità significati-ve del Disegno di Architettura, che consenta riflessioni dedicate alle sue varie dimensioni, oggi più che mai da approfondire. La suggestione a farlo, viene da un’idea di Pablo Rodri-guez Navarro ed abbiamo quindi pensato di avviarla proprio in questo numero, che Pablo ha accettato di curare su un tema a lui particolarmente caro.

  19. Filtros de vena cava en pacientes con cáncer

    Directory of Open Access Journals (Sweden)

    Fernando A. Díaz Couselo

    2012-08-01

    Full Text Available Los pacientes con tromboembolismo venoso (TEV y cáncer tienen más complicaciones vinculadas al tratamiento anticoagulante que la población general. Los filtros de vena cava constituyen una herramienta útil para el tratamiento del TEV y su utilización es controvertida en estadios avanzados de la enfermedad. En este trabajo se revisaron las indicaciones, complicaciones y frecuencia de retiro de los filtros de vena cava en una población de pacientes oncológicos con TEV. Se analizaron 27 pacientes a quienes se les había colocado filtros de vena cava. Veinticinco tenían tumores sólidos y dos linfomas no Hodgkin. Veinticinco estaban bajo tratamiento activo (cirugía y/o quimioterapia. Diecinueve se hallaban en estadio IV de su enfermedad. El motivo de su indicación fue profilaxis en el período perioperatorio en 14 casos (51.9%, hemorragia (n = 5, trombocitopenia (n = 4, metástasis en sistema nervioso central (n = 2, accidente cerebrovascular (n = 1 y neurocirugía previa no reciente (n = 1. Se retiraron 8 (29.6% filtros. La mediana del tiempo de permanencia fue 21 días (6-75. No hubo diferencias estadísticamente significativas en la frecuencia de retiro entre los filtros colocados en el perioperatorio (6/14 y los colocados por otras contraindicaciones para la anticoagulación (2/13; p = 0.2087. No hubo fracasos ni complicaciones en los procedimientos de colocación y retiro.

  20. Mucormicosis yeyunal en paciente con linfoma de Hodgkin Jejunal mucormycosis in a patient with Hodgkin's lymphoma

    Directory of Open Access Journals (Sweden)

    B. Madrigal

    2008-08-01

    Full Text Available Comunicamos un caso de mucormicosis intestinal en un hombre de 46 años de edad, diagnosticado de enfermedad de Hodgkin clásica, estadio IV-B. Durante la primera fase de la quimioterapia, sufrió una hemorragia digestiva masiva secundaria a una úlcera yeyunal por zigomicosis tipo mucor, diagnosticada por biopsia endoscópica. El paciente fue tratado con antifúngicos y resección quirúrgica del intestino afectado. En la cirugía, se apreció una doble perforación yeyunal cubierta. El estudio anatomopatológico de la pieza confirmó el diagnóstico previo. Tras un año de seguimiento, el paciente está recuperado y su linfoma de Hodgkin en remisión completa. Tras una extensa revisión de la literatura, según nuestro conocimiento, este es el segundo caso publicado en la literatura de mucormicosis intestinal en un paciente con linfoma de Hodgkin.We report a case of intestinal mucormycosis in a 46-year-old male diagnosed with classical Hodgkin's disease, IV-B stage. During the first phase of chemotherapy he had a massive digestive bleeding event secondary to a jejunal ulcer, and zygomicosis mucor-type was diagnosed by endoscopic biopsy. The patient was treated with antifungal drugs and surgical resection of the intestine involved. At surgery a double covered perforation of the jejunum was seen. Pathological examination confirmed the previous diagnosis. After one year of follow-up the patient is doing well, and his lymphoma is on remission. To our best knowledge this is the second case of intestinal mucormycosis in a patient with Hodgkin's lymphoma reported in the medical literature.

  1. Is there a relationship between patient satisfaction and favorable outcomes?

    Science.gov (United States)

    Kennedy, Gregory D; Tevis, Sarah E; Kent, K Craig

    2014-10-01

    Patient satisfaction with the health care experience has become a top priority for Centers for Medicare and Medicaid Services. With resources and efforts directed at patient satisfaction, we evaluated whether high patient satisfaction measured by HCAHPS (Hospital Consumer Assessment of Healthcare Providers and Systems) surveys correlates with favorable outcomes. Medical centers were identified from the University HealthSystem Consortium database from 2011 to 2012. Variables included hospital characteristics, process measure compliance, and surgical outcomes. Chi-squared analysis was used to evaluate for variables associated with high patient satisfaction (defined as hospitals that scored above the 50th percentile of top box scores). We identified 171 hospitals with complete data. The following variables were significantly associated with high overall patient satisfaction: large hospitals, high surgical volume, and low mortality (P patient satisfaction. Low mortality index was consistently found to be associated with high satisfaction across 9 of 10 HCAHPS domains. We found that hospital size, surgical volume, and low mortality were associated with high overall patient satisfaction. However, with the exception of low mortality, favorable surgical outcomes were not consistently associated with high HCAHPS scores. With existing satisfaction surveys, we conclude that factors outside of surgical outcomes appear to influence patients' perceptions of their care.

  2. Science Curriculum Components Favored by Taiwanese Biology Teachers

    Science.gov (United States)

    Lin, Chen-Yung; Hu, Reping; Changlai, Miao-Li

    2005-09-01

    The new 1-9 curriculum framework in Taiwan provides a remarkable change from previous frameworks in terms of the coverage of content and the powers of teachers. This study employs a modified repertory grid technique to investigate biology teachers' preferences with regard to six curriculum components. One hundred and eighty-five in-service and pre-service biology teachers were asked to determine which science curriculum components they liked and disliked most of all to include in their biology classes. The data show that the rank order of these science curriculum components, from top to bottom, was as follows: application of science, manipulation skills, scientific concepts, social/ethical issues, problem-solving skills, and the history of science. They also showed that pre-service biology teachers, as compared with in-service biology teachers, favored problem-solving skills significantly more than manipulative skills, while in-service biology teachers, as compared with pre-service biology teachers, favored manipulative skills significantly more than problem-solving skills. Some recommendations for ensuring the successful implementation of the Taiwanese 1-9 curriculum framework are also proposed.

  3. Positive Surgical Margins in Favorable-Stage Differentiated Thyroid Cancer.

    Science.gov (United States)

    Mercado, Catherine E; Drew, Peter A; Morris, Christopher G; Dziegielewski, Peter T; Mendenhall, William M; Amdur, Robert J

    2018-04-16

    The significance of positive margin in favorable-stage well-differentiated thyroid cancer is controversial. We report outcomes of positive-margin patients with a matched-pair comparison to a negative-margin group. A total of 25 patients with classic-histology papillary or follicular carcinoma, total thyroidectomy +/- node dissection, stage T1-3N0-1bM0, positive surgical margin at primary site, adjuvant radioactive iodine (I-131), and age older than 18 years were treated between 2003 and 2013. Endpoints were clinical and biochemical (thyroglobulin-only) recurrence-free survival. Matched-pair analysis involved a 1:1 match with negative-margin cases matched for overall stage and I-131 dose. Recurrence-free survival in positive-margin patients was 71% at 10 years. No patient was successfully salvaged with additional treatment. Only 1 patient died of thyroid cancer. Recurrence-free survival at 10 years was worse with a positive (71%) versus negative (90%) margin (P=0.140). Cure with a microscopically positive margin was suboptimal (71%) despite patients having classic-histology papillary and follicular carcinoma, favorable stage, and moderate-dose I-131 therapy.

  4. Conversando con Oriol Bohigas

    OpenAIRE

    Redondo Domínguez, Ernesto; Moya Sala, Joaquim

    2015-01-01

    [EN] Interview with Oriol Bohigas [ES] Entrevista con Oriol Bohigas Redondo Domínguez, E.; Moya Sala, J. (2015). Conversando con… Oriol Bohigas. EGA. Revista de Expresión Gráfica Arquitectónica. 20(26):22-35. doi:10.4995/ega.2015.4061 22 35 20 26

  5. DR Con o:

    African Journals Online (AJOL)

    which could fall under the Ugandan influence. The con-. flict in the ..... The Congolese people and international community within SADC, the AU ..... ments and make peace among themselves. However, one ... friends overnight.There is a great ...

  6. fertilizada con diferentes abonos

    Directory of Open Access Journals (Sweden)

    Jorge Alberto Elizondo-Salazar

    2007-01-01

    Full Text Available Producción y calidad de la biomasa de morera (Morus alba fertilizada con diferentes abonos. Se llevó a cabo un experimento en la Estación Experimental “Alfredo Volio Mata” de la Universidad de Costa Rica con el fi n de evaluar la aplicación de 150 kg de N/ha/año proveniente de dos abonos orgánicos: lombriabono y compostaje; y de un fertilizante químico, sobre la producción y calidad de la biomasa de morera. El periodo experimental comprendió un ciclo de 12 meses, iniciando en julio del 2003 y fi nalizando en julio del 2004. Se utilizó una plantación de morera de 12 años de establecida con una densidad de siembra de 27.777 plantas/ ha. Se empleó un diseño de bloques completos al azar con cuatro tratamientos: dos abonos orgánicos, nitrato de amonio (33,5% N y un control. Las plantas se podaron a 0,6 m sobre el nivel del suelo al inicio del ensayo. Durante el periodo experimental, las plantas fueron podadas consecutivamente cada 90 días. Las hojas y los tallos fueron separados y analizados para determinar el contenido de materia seca y proteína cruda. La producción de materia seca fue 23% superior y el contenido de proteína cruda fue signifi cativamente mayor con el nitrógeno químico, mientras que el contenido de materia seca fue menor. No se encontraron diferencias signifi cativas entre el tratamiento control y los tratamientos orgánicos.

  7. Cuadro clínico patológico y factores pronósticos de sobrevida en adultos con sarcomas de partes blandas

    Directory of Open Access Journals (Sweden)

    Juan Díaz-Plasencia

    1997-10-01

    Full Text Available Objetivo: Identificar el cuadro clínico - patológico y algunos factores pronósticos que influyen en la sobrevida actuarial a 5 años. Material y métodos: Analizamos retrospectivamente información de 44 adultos portadores de sarcomas de partes blandas tratados en el Hospital Belén, Perú, desde 1967 a 1994. La estimación de la sobrevida fue hecha por el método de Kaplan - Meier y en el análisis univariado utilizamos el test de log - rank. Resultados: La edad promedio fue de 46 ± 19 años (límites, 16 a 85 años. Hubo 21 hombres y 23 mujeres (H:M, 0,9:1. Las molestias más frecuentes fueron tumor y dolor local. Las localizaciones más afectadas fueron las extremidades inferiores (52% y superiores (21%. De acuerdo a la clasificación UICC, 48% de los casos estuvieron en estadio II. 23 % en estadio III, 18 % en estadio IV y 11 % en estadio I. Los tipos histológicos predominantes fueron: Fibrosarcoma (34 %, liposarcoma (16 % y rabdomiosarcoma (14 %. Trece tumores (30 % fueron clasificados como grado 3, 24 (55% como grado 2 y 7 (16 % como grado 1. La sobrevida a 5 años fue de 54 % con cirugía sola (n=27, 11 % con cirugía más radioterapia y/o quimioterapia (n=13 y 0% con radioterapia y /o quimioterapia (n=4 (p< 0.01. La sobrevida a 5 años en la serie total fue 38 %. Fueron factores que influyeron en la sobrevida: Edad (p< 0.001, tiempo de enfermedad (p <0.001, estado ganglionar regional (p <0.001, grado histológico (p < 0.01, estadio clínico (p <0.001 y tipo de tratamiento (p <0.001. Conclusión: El tratamiento de elección para los sarcomas de partes blandas es la cirugía de amplio margen. (Rev Med Hered 1997; 8: 129-141.

  8. Preliminary study of the uranium favorability of Malheur County, Oregon

    International Nuclear Information System (INIS)

    Erikson, E.H.

    1977-11-01

    A reconnaissance study of middle and upper Tertiary volcaniclastic sedimentary and silicic volcanic rocks in Malheur County, Oregon, indicates that, based upon the data available: (1) it is unlikely that sandstone-type uranium deposits exist in sedimentary rocks of north-central Malheur County; and (2) favorable uranium environments are more likely to exist in and adjacent to uraniferous silicic eruptive centers and plugs. Some rhyolites in the northern part of the county contain marginally anomalous uranium abundances (6 to 8 +- 2 ppM U 3 O 8 ), compared with similar rocks in southeastern Oregon. Available uranium from these rocks, as determined by nitric-acid leaching, approaches 50 to 75 percent of the total chemical U 3 O 8 present. One Pliocene rhyolite vitrophyre sample from Duck Butte in western Malheur County contains 9 +- 2 ppM U 3 O 8 . The uranium contents of these rhyolites approach those found in silicic plugs spatially related to uranium deposits in the Lakeview district, Oregon (Erikson and Curry, 1977). It is possible that undiscovered epithermal and (or) supergene uranium deposits may exist in favorable wall rocks subjacent to uraniferous silicic eruptive centers (Duck Butte), calderas (McDermitt caldera to the south and others identified in western Owyhee County, Idaho), and silicic plugs (as in the Lakeview district). With the exception of one small uranium anomaly found in unconsolidated sands in the Grassy Mountain Formation, the sedimentary rocks observed in the study area did not possess abnormal radioactivity or exhibit evidence of uranium mobility and enrichment. Carbonaceous trash is uncommon in these rocks. Gently dipping sandstone members of the Deer Butte Formation (upper Miocene) and local channel sands in the Grassy Mountain Formation (Pliocene) may have once been the most permeable rocks in the Tertiary section; but, there is no evidence to suggest that they were conduits for uranium-bearing solutions

  9. pacientes con falla cardiaca

    Directory of Open Access Journals (Sweden)

    Diana Marcela Achury Saldaña

    2007-01-01

    Full Text Available Objetivo: determinar la adherencia al tratamiento de pacientes con falla cardiaca hospitalizados, al aplicar un plan educativo quefomenta el autocuidado.Método: estudio cuasiexperimental (entrevistas enfermera-paciente realizado entre diciembre de 2004 y mayo de 2006, con unamuestra de 50 pacientes seleccionados por conveniencia. Se diseñó un instrumento para evaluar los comportamientos de los pacientes,con base en algunos resultados de la adherencia y sus respectivos indicadores de la taxonomía NOC (Nursing out comes classification. Laadherencia al tratamiento fue medida en dos momentos: el primero durante la hospitalización, seguido de la aplicación del plan educativoantes del alta, que proporcionaba información en el manejo de su enfermedad desde una dimensión física, psicológica y social quepromueve el autocuidado; y el segundo un mes después del alta en su domicilio.Resultados: diferencias estadísticamente significativas (P=0,0001 que demuestran cómo mediante la capacitación al paciente enel manejo de su tratamiento farmacológico y no farmacológico, el establecimiento de una sana relación entre el profesional de enfermeríay el paciente, y la participación de la familia, se logra una total adherencia al tratamiento.Conclusiones: para lograr una adherencia total del paciente con falla cardiaca al tratamiento es necesario un proceso educativo y unseguimiento continuo y personalizado que motive permanentemente al paciente y se le reconozca el papel protagónico en su cuidado y manejo de la enfermedad.

  10. Pig as a Favorable Animal for Taenia Saginata Asiatica Infection

    Directory of Open Access Journals (Sweden)

    Ping-Chin Fan

    2006-01-01

    Full Text Available The epidemiology of Taenia saginata in some parts of Asia is confusing, in that beef does not appear to be the source of infection. In some areas, beef is either not available or not eaten raw, whereas pork at times is eaten uncooked. In light of this situation, we have exposed pigs and other animals to infection with strains of T. saginata to establish their ability to serve as intermediate hosts. Eggs of Taiwan Taenia, Korea Taenia, Indonesia Taenia, Thailand Taenia, Philippines Taenia, Ethiopia Taenia, and Madagascar Taenia were fed to 83 pigs of three strains: 43 Small-Ear Miniature (SEM, 34 Landrace Small-Ear Miniature (L-SEM, and 6 Duroc-Yorkshire-Landrace (DYL. We also fed the eggs to 10 Holstein calves, 17 Sannean goats, and 4 monkeys (Macaca cyclopis. We succeeded in infecting SEM (infection rate 88%, cysticercus recovery rate 19.1%, L-SEM (83%, 1.1%, and DYL (100%, 0.3% pigs with Taiwan Taenia; SEM (100%, 1.7%, L-SEM (100%, 5.6%, and DYL (100%, 0.06% pigs with Korea Taenia; SEM (100%, 22% and L-SEM (100%, 1.6% pigs with Indonesia Taenia; SEM (75%, 0.06% pigs with Thailand Taenia SEM (100%, 11% pigs with Philippines Taenia; SEM (80%, 0.005% pigs with Ethiopia Taenia; SEM (100%, 0.2% pigs with Madagascar Taenia. Holstein calves became infected with Taenia from Taiwan (100%, 1.1%, Korea (100%, 0.03%, Thailand (100%, 0.2%, and the Philippines (100%, 6%; however, the cysticerci of Taenia from Korea, Thailand, and the Philippines were degenerated and/or calcified. Sannean goats became infected with Taenia from Taiwan (33%, 0.01% and Korea (50%, 0.02%, while monkeys became infected with Taenia from Taiwan (50%, 0.01%. However, the cysticerci were degenerated and/or calcified. Therefore, these strains of pig seem to be favorable animal models for experimental studies of T. saginata-like tapeworms, with the SEM pig the most favorable.

  11. Paleozoic unconformities favorable for uranium concentration in northern Appalachian basin

    International Nuclear Information System (INIS)

    Dennison, J.M.

    1986-01-01

    Unconformities can redistribute uranium from protore rock as ground water moves through poorly consolidated strata beneath the erosion surface, or later moves along the unconformity. Groundwater could migrate farther than in present-day lithified Paleozoic strata in the Appalachian basin, now locally deformed by the Taconic and Allegheny orogenies. Several paleoaquifer systems could have developed uranium geochemical cells. Sandstone mineralogy, occurrences of fluvial strata, and reduzate facies are important factors. Other possibilities include silcrete developed during desert exposure, and uranium concentrated in paleokarst. Thirteen unconformities are evaluated to determine favorable areas for uranium concentration. Cambrian Potsdam sandstone (New York) contains arkoses and possible silcretes just above crystalline basement. Unconformities involving beveled sandstones and possible fluvial strata include Cambrian Hardyston sandstone (New Jersey), Cambrian Potsdam Sandstone (New York), Ordovician Oswego and Juniata formations (Pennsylvania and New York), Silurian Medina Group (New York), and Silurian Vernon, High Falls, and Longwood formations (New York and New Jersey). Devonian Catskill Formation is beveled by Pennsylvanian strata (New York and Pennsylvania). The pre-Pennsylvanian unconformity also bevels Lower Mississippian Pocono, Knapp, and Waverly strata (Pennsylvania, New York, and Ohio), truncates Upper Mississippian Mauch Chunk Formation (Pennsylvania), and forms paleokarst on Mississippian Loyalhanna Limestone (Pennsylvania) and Maxville Limestone (Ohio). Strata associated with these unconformities contain several reports of uranium. Unconformities unfavorable for uranium concentration occur beneath the Middle Ordovician (New York), Middle Devonian (Ohio and New York), and Upper Devonian (Ohio and New York); these involve marine strata overlying marine strata and probably much submarine erosion

  12. Interaction Heterogeneity can Favorably Impact Colloidal Crystal Nucleation

    Science.gov (United States)

    Jenkins, Ian C.; Crocker, John C.; Sinno, Talid

    2017-10-01

    Colloidal particles with short-ranged attractions, e.g., micron-scale spheres functionalized with single-stranded DNA oligomers, are susceptible to becoming trapped in disordered configurations even when a crystalline arrangement is the ground state. Moreover, for reasons that are not well understood, seemingly minor variations in the particle formulation can lead to dramatic changes in the crystallization outcome. We demonstrate, using a combination of equilibrium and nonequilibrium computer simulations, that interaction heterogeneity—variations in the energetic interactions among different particle pairs in the population—may favorably impact crystal nucleation. Specifically, interaction heterogeneity is found to lower the free energy barrier to nucleation via the formation of clusters comprised preferentially of strong-binding particle pairs. Moreover, gelation is inhibited by "spreading out over time" the nucleation process, resulting in a reduced density of stable nuclei, allowing each to grow unhindered and larger. Our results suggest a simple and robust approach for enhancing colloidal crystallization near the "sticky sphere" limit, and support the notion that differing extents of interaction heterogeneity arising from various particle functionalization protocols may contribute to the otherwise unexplained variations in crystallization outcomes reported in the literature.

  13. Occurrence of clinical mastitis and environmental factors favoring its incidence

    Directory of Open Access Journals (Sweden)

    Elisa Junqueira Oliveira

    2013-02-01

    Full Text Available The objective of this study was to evaluate the frequency of clinical mastitis (CM, in high production Holstein cows, as well as the environmental factors that favoring its incidence. The average milk production of 305 days, according to the class of mastitis was estimated by the method of least squares. The frequencies of clinical mastitis (CM events were analyzed according to the calving sequences (1-6, year of calving, season and stage of lactation, and infected quarter (right anterior, left anterior, right posterior, left posterior. The frequency of CM ranged from 11.39% in the first calving to 21.18% in the third. 58.56% of mastitis cases occurred in the wet season, and 41.44% occurred in the dry season. The final lactation stage (200 to 300 days was the period with the highest occurrence of CM (45.33%. The quarter posterior had a higher frequency CM (54.25%. Animals with higher levels of milk production of 305 days showed highest occurrence of CM. We must find a balance between milk production and mastitis in order to increase profitability. The study of the periods of greatest frequency clinical mastitis events is essential for dairy farming, to direct a program to control this disease.

  14. Competition favors elk over beaver in a riparian willow ecosystem

    Science.gov (United States)

    Baker, B.W.; Peinetti, H.R.; Coughenour, M.C.; Johnson, T.L.

    2012-01-01

    Beaver (Castor spp.) conservation requires an understanding of their complex interactions with competing herbivores. Simulation modeling offers a controlled environment to examine long-term dynamics in ecosystems driven by uncontrollable variables. We used a new version of the SAVANNA ecosystem model to investigate beaver (C. Canadensis) and elk (Cervus elapses) competition for willow (Salix spp.). We initialized the model with field data from Rocky Mountain National Park, Colorado, USA, to simulate a 4-ha riparian ecosystem containing beaver, elk, and willow. We found beaver persisted indefinitely when elk density was or = 30 elk km_2. The loss of tall willow preceded rapid beaver declines, thus willow condition may predict beaver population trajectory in natural environments. Beaver were able to persist with slightly higher elk densities if beaver alternated their use of foraging sites in a rest-rotation pattern rather than maintained continuous use. Thus, we found asymmetrical competition for willow strongly favored elk over beaver in a simulated montane ecosystem. Finally, we discuss application of the SAVANNA model and mechanisms of competition relative to beaver persistence as metapopulations, ecological resistance and alternative state models, and ecosystem regulation.

  15. Heterolytic dissociative adsorption state of dihydrogen favored by interfacial defects

    Science.gov (United States)

    Song, Zhenjun; Hu, Hanshi; Xu, Hu; Li, Yong; Cheng, Peng; Zhao, Bin

    2018-03-01

    The atomic-scale insight into dihydrogen on MgO(001) surface deposited on molybdenum substrate with interfacial defects was investigated in detail by employing density functional methods Here we report novel dissociative adsorption behaviors of single hydrogen molecule on the usually inert oxide surfaces, with consideration of two types of dissociation schemes. The heterolytic dissociation state -Mg(H)-O(H)- of dihydrogen is impossible to obtain on neighboring O-Mg sites of perfect bulk MgO(001) terraces. Unusually, the hydrogen molecule can form heterolytic fragmentation states on metal supported MgO(001) films with very low activation barrier (0.398 eV), and the heterolytic dissociation state is much more favorable than homolytic dissociation state both energetically and kinetically in all cases. Electronic properties and bonding attribution of adsorbates and the oxide-metal hybrid structure are revealed by analyzing density of states, differential charge densities, orbital interaction and electron localization function. The characteristic changes to the property and activity of magnesia (001) can have potential application in catalytic reactions.

  16. Cementos con cenizas volantes

    Directory of Open Access Journals (Sweden)

    Ossa M., Mauricio

    1984-03-01

    additions of 20 and 30% .

    Casi la generalidad de los estudios realizados sobre cementos con adición de cenizas volantes se refieren a sus características y comportamiento en pastas, morteros y hormigones, siempre en relación con aquéllos del cemento portland. Esta vez, se desarrolló un trabajo experimental orientado a relacionar entre sí los cementos con adiciones de cenizas volantes y de puzolana natural. Para ello se fabricaron a escala de laboratorio cementos de ambos tipos, empleando como materias primas comunes clinker y yeso y, como variables, diferentes porcentajes de las dos adiciones, que cumplieron previamente los requisitos normalizados en cuanto a sus actividades puzolánicas. La calidad de los cementos fabricados resultó adecuada y concordante con la del cemento portland-puzolánico obtenido a escala industrial con los mismos clinker, yeso y puzolana natural de este estudio. Posteriormente, se determinaron las características de los cementos experimentales y se confeccionaron morteros normales para la realización de ensayos físicos y mecánicos. Los resultados de ensayos indicaron que los cementos con adición de cenizas volantes (CCV requieren menos agua para consistencia normal, presentan tiempos de fraguado mayores y expansiones en autoclave menores que los cementos con adición de puzolana (CP. Los calores de hidratación a 7 y 28 días de edad fueron aproximadamente similares para ambos tipos de cemento. En morteros normales, los cementos CCV mostraron menor retracción de secado, mayor retentividad y mayor fluidez (para igual cantidad de agua que los cementos CP. En los ensayos de exudación se observó que ésta depende más de la finura que el tipo de adición. Finalmente, los ensayos mecánicos señalaron que las resistencias a compresión y flexotracción de los morteros con cementos CCV son menores a edades inferiores que 14 días (del orden de 5 a 10% a un día de edad, pero que a partir de entonces pasan a ser mayores que las de

  17. Tratamento com radio e quimioterapia do carcinoma epidermóide do canal anal: experiência do hospital Barão de Lucena Radiochemotherapy for squamous cell carcinoma of the anal canal: Barao de Lucena hospital experience

    Directory of Open Access Journals (Sweden)

    Maurilio Toscano de Lucena

    2010-06-01

    Full Text Available Objetivos: Apresentar os resultados e analisar as variáveis implicadas no tratamento e prognóstico do carcinoma epidermóide do canal anal tratado através da radio e quimioterapia no Hospital Barão de Lucena-SUS-PE. Metodologia: Análise dos prontuários de pacientes com diagnóstico de câncer do canal anal submetidos a tratamento radioquimioterápico. O período de acompanhamento foi de junho de 1989 a junho de 2005. Foram incluídos os pacientes com diagnóstico histológico de câncer de canal anal, enquadrados nos estadios I, II, IIIa e IIIb, submetidos a dois ciclos de quimioterapia com 5-fluorouracil (5-FU na dose de 1g/m²/dia em infusão contínua de 96 horas e cisplatino na dose de 100mg/m² administrado em 6 horas no segundo dia de infusão de cada ciclo, administrados na primeira e terceira semanas do esquema de tratamento radioterápico. Resultados: Avaliamos 108 prontuários de pacientes que preencheram os critérios do protocolo. O tempo médio de seguimento foi de 51 meses (1-182 meses. Houve predomínio do gênero feminino (81,5% dos pacientes. A idade variou de 33 a 83 anos (média de 59 anos. O tipo histológico mais freqüente foi o carcinoma de células escamosas (80,6% dos casos. Em 21 pacientes, foi diagnosticado carcinoma basalóide. Quanto ao grau de diferenciação, prevaleceu o tipo moderadamente diferenciado (61% dos pacientes com carcinoma de células escamosas. O índice de resposta inicial completa foi de 89,8%. Onze pacientes persistiram com tumor após o tratamento radio e quimioterápico. O índice de resposta inicial completa foi menor nos estadios IIIa e IIIb em relação aos estadios I e II com significância estatística (pObjectives: To present the results and analyze the variables involved in the treatment and prognosis of squamous cell carcinoma of the anal canal treated by radiotherapy and chemotherapy at the Hospital Barao de Lucena-SUS-PE. Methodology: Analysis of medical records of patients

  18. competencia con China

    Directory of Open Access Journals (Sweden)

    Elena de la Paz Hernández Águila

    2007-01-01

    Full Text Available El artículo ofrece un diagnóstico del desempeño de la industria mexicana del calzado desde la década de los ochenta hasta la actualidad. Analiza la problemática que ha enfrentado esta rama industrial a partir del proceso de apertura comercial y de la competencia en su mercado interno con productos provenientes de países asiáticos, particularmente China. Problematiza al respecto los retos y las perspectivas que a mediano plazo enfrentará este sector empresarial y sobre las posibilidades de competir en el mercado globalizado.

  19. Construir con Madera

    OpenAIRE

    Olabe-Velasco, F. (Fermín); Val-Hernández, Y. (Yolanda); Varela-de-la-Cruz, P. (Perla); Cabrero-Ballarín, J.M. (José Manuel)

    2010-01-01

    Guía divulgativa ‘Construir con madera’, elaborada por la Cátedra Madera de la Universidad de Navarra y el Gobierno de Navarra. La publicación pretende explicar de forma sencilla los beneficios y posibilidades de este material en la construcción, tanto en lo que respecta a su resistencia, comportamiento frente al fuego, durabilidad, capacidad de aislamiento, propiedades acústicas, estética, respeto al medio ambiente y sostenibilidad como fuente de energía. A modo de ejemplo, en la ...

  20. Preliminary study of uranium favorability of the Boulder batholith, Montana

    International Nuclear Information System (INIS)

    Castor, S.B.; Robins, J.W.

    1978-01-01

    The Boulder batholith of southwestern Montana is a composite Late Cretaceous intrusive mass, mostly composed of quartz monzonite and granodiorite. This study was not restricted to the plutonic rocks; it also includes younger rocks that overlie the batholith, and older rocks that it intrudes. The Boulder batholith area has good overall potential for economic uranium deposits, because its geology is similar to that of areas that contain economic deposits elsewhere in the world, and because at least 35 uranium occurrences of several different types are present. Potential is greatest for the occurrence of small uranium deposits in chalcedony veins and base-metal sulfide veins. Three areas may be favorable for large, low-grade deposits consisting of a number of closely spaced chalcedony veins and enriched wall rock; the Mooney claims, the Boulder area, and the Clancy area. In addition, there is a good possibility of by-product uranium production from phosphatic black shales in the project area. The potential for uranium deposits in breccia masses that cut prebatholith rocks, in manganese-quartz veins near Butte, and in a shear zone that cuts Tertiary rhyolite near Helena cannot be determined on the basis of available information. Low-grade, disseminated, primary uranium concentrations similar to porphyry deposits proposed by Armstrong (1974) may exist in the Boulder batholith, but the primary uranium content of most batholith rocks is low. The geologic environment adjacent to the Boulder batholith is similar in places to that at the Midnite mine in Washington. Some igneous rocks in the project area contain more than 10 ppM U 3 O 8 , and some metasedimentary rocks near the batholith contain reductants such as sulfides and carbonaceous material

  1. Cordilleran metamorphic core complexes and their uranium favorability. Final report

    International Nuclear Information System (INIS)

    Coney, P.J.; Reynolds, S.J.

    1980-11-01

    The objective of this report is to provide a descriptive body of knowledge on Cordilleran metamorphic core complexes including their lithologic and structural characteristics, their distribution within the Cordillera, and their evolutionary history and tectonic setting. The occurrence of uranium in the context of possibility for uranium concentration is also examined. Chapter 1 is an overview of Cordilleran metamorphic core complexes which describes their physical characteristics, tectonic setting and geologic history. This overview is accompanied by a tectonic map. Chapter 2 is a discussion of the mantled gneiss dome concept. The purpose of including this work is to provide a basic history of this concept and to describe the characteristics and distribution of gneiss domes throughout the world to enable one to compare and contrast them with the metamorphic core complexes as discussed in this report. Some gneiss domes are known producers of uranium (as are also some core complexes). Chapter 3 is an examination of the effects of the core complex process on adjacent sedimentary and volcanic cover terranes. Also included is a discussion of the kinematic significance of these cover terranes as they are related to process within the cores of the complexes. Some of the cover terranes have uranium prospects in them. Chapter 4 is a detailed discussion of uranium in Cordilleran metamorphic core complexes and includes the conceptual basis for the various types of occurrences and the processes that might favor concentration of uranium. The report is supported by a 5-part Appendix. The majority of the core complexes discussed in this report either do not appear or are not recognizable on existing published geologic maps

  2. Preliminary study of uranium favorability of the Boulder batholith, Montana

    Energy Technology Data Exchange (ETDEWEB)

    Castor, S.B.; Robins, J.W.

    1978-01-01

    The Boulder batholith of southwestern Montana is a composite Late Cretaceous intrusive mass, mostly composed of quartz monzonite and granodiorite. This study was not restricted to the plutonic rocks; it also includes younger rocks that overlie the batholith, and older rocks that it intrudes. The Boulder batholith area has good overall potential for economic uranium deposits, because its geology is similar to that of areas that contain economic deposits elsewhere in the world, and because at least 35 uranium occurrences of several different types are present. Potential is greatest for the occurrence of small uranium deposits in chalcedony veins and base-metal sulfide veins. Three areas may be favorable for large, low-grade deposits consisting of a number of closely spaced chalcedony veins and enriched wall rock; the Mooney claims, the Boulder area, and the Clancy area. In addition, there is a good possibility of by-product uranium production from phosphatic black shales in the project area. The potential for uranium deposits in breccia masses that cut prebatholith rocks, in manganese-quartz veins near Butte, and in a shear zone that cuts Tertiary rhyolite near Helena cannot be determined on the basis of available information. Low-grade, disseminated, primary uranium concentrations similar to porphyry deposits proposed by Armstrong (1974) may exist in the Boulder batholith, but the primary uranium content of most batholith rocks is low. The geologic environment adjacent to the Boulder batholith is similar in places to that at the Midnite mine in Washington. Some igneous rocks in the project area contain more than 10 ppM U/sub 3/O/sub 8/, and some metasedimentary rocks near the batholith contain reductants such as sulfides and carbonaceous material.

  3. Entrevista con Giovanni Levi

    Directory of Open Access Journals (Sweden)

    Monica Oliveira

    2017-06-01

    Full Text Available En esta entrevista, Giovanni Levi - como un conocedor del tema de Familia - realiza una importante evaluación sobre el actual estado de las investigaciones realizadas en el Brasil y em el exterior. Con estilo franco, agudo y lucido critica las visiones tradicionales y sus ilusiones ypropone nuevos conceptos y métodos. La historia de la familia debería ceder espacio para el estudio de las redes relacionales o de los mundos relacionales. De la misma forma, la historia cuantitativa debería abrir espacio para el estudio de las cualidades. Ya con relación a la historia de las elites, tan estudiada y reproducida en una diversidad de trabajos, que deberíase mirar en otra perspectiva. Es decir, no mirar a las reglas sociales predeterminadas, sino a los desvíos y a las variaciones. Levi defiende que los historiadores deben trascender a los documentos que se encuentran fácilmente y que pueden fortalecer perspectivas deformadas y esequilibradas de la sociedad. Para él, los historiadores deben esforzarse por estudiar a aquellos grupos que dejaron pocos rastros documentales. En ese esfuerzo existiría una nueva mirada sobre la historia de la familia.

  4. Entrevista con Patricia Ariza

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    Esperanza Londoño La Rotta

    2017-01-01

    Full Text Available Pensamiento, Palabra y Obra entrevista a una artista, feminista y activista política, quien como mujer y artista ha permitido pensar el arte más allá de un simple espectáculo. Toda una vida dedicada al teatro y a darle voz, a través de sus obras, a víctimas del conflicto colombiano, defensora de derechos humanos; además de hacer evidente en su vida y a través de la plataforma “Artistas por la paz”, las múltiples relaciones que se pueden establecer entre el arte, la construcción de paz y la resolución de conflictos. Hablamos en su casa, en medio del calor de la bienvenida con Patricia Ariza, directora del festival alternativo de teatro, de Mujeres en Escena y de la Corporación Colombiana de Teatro, entre otras muchas actividades que voluntariamente su espíritu libertario ha asumido. Esta entrevista se realizó antes del 2 de octubre, pero con la revisión de los acuerdos que propició el plebiscito ganado por una ínfima minoría por el no, sigue siendo vigente este planteamiento.

  5. Chemotherapy versus best supportive care in stage IV non-small cell lung cancer, non metastatic to the brain Quimioterapia versus melhor tratamento de suporte em câncer de pulmão estádio clínico IV não metastático para o sistema nervoso central

    Directory of Open Access Journals (Sweden)

    Agnaldo Anelli

    2001-04-01

    Full Text Available Stage IV non-small cell lung cancer is a fatal disease, with a median survival of 14 months. Systemic chemotherapy is the most common approach. However the impact in overall survival and quality of life still a controversy. OBJECTIVES: To determine differences in overall survival and quality of life among patients with stage IV non-small cell lung cancer non-metastatic to the brain treated with best supportive care versus systemic chemotherapy. PATIENTS: From February 1990 through December 1995, 78 eligible patients were admitted with the diagnosis of stage IV non-small cell lung cancer . Patients were divided in 2 groups: Group A (n=31 -- treated with best supportive care , and Group B (n=47 -- treated with systemic chemotherapy. RESULTS: The median survival time was 23 weeks (range 5 -- 153 weeks in Group A and 55 weeks (range 7.4 -- 213 weeks in Group B (p=0.0018. In both groups, the incidence of admission for IV antibiotics and need of blood transfusions were similar. Patients receiving systemic chemotherapy were also stratified into those receiving mytomycin, vinblastin, and cisplatinum, n=25 and those receiving other combination regimens (platinum derivatives associated with other drugs, n=22. Patients receiving mytomycin, vinblastin, and cisplatinum, n=25 had a higher incidence of febrile neutropenia and had their cycles delayed for longer periods of time than the other group. These patients also had a shorter median survival time (51 versus 66 weeks, p=0.005. CONCLUSION: In patients with stage IV non-small cell lung cancer, non-metastatic to the brain, chemotherapy significantly increases survival compared with best supportive care.O câncer de pulmão de células não pequenas em estádio IV é uma doença fatal, com uma sobrevida mediana de seis meses. Quimioterapia é a abordagem mais freqüente, apresentando um impacto na sobrevida controverso e questionável alteração na qualidade de vida. OBJETIVOS: Comparar o impacto na

  6. Efectividad del ejercicio físico en la fatiga de pacientes con cáncer durante el tratamiento activo: revisión sistemática y metaanálisis

    Directory of Open Access Journals (Sweden)

    Jose Francisco Meneses-Echávez

    2015-04-01

    Full Text Available El objetivo del estudio fue determinar la efectividad del ejercicio físico en la fatiga de pacientes con cáncer durante el tratamiento activo. Las bases de datos de PubMed Central, EMBASE y OVID fueron consultadas hasta abril de 2014 para identificar ensayos clínicos aleatorizados, que evaluaran el efecto del ejercicio en la fatiga de pacientes con cáncer sometidos a tratamiento activo. Once estudios (n = 1.407 fueron incluidos. La quimioterapia fue el tratamiento más común (n = 1.028. Los estudios tuvieron bajo riesgo de sesgo y alta calidad metodológica. Las estimaciones de efecto mostraron que el ejercicio físico mejoró significativamente la fatiga (SMD = -3,0; IC95%: -5,21; -0,80, p < 0,0001. Se encontraron efectos similares para el entrenamiento de resistencia (SMD = -4,5; IC95%: -7,24; -1,82, p = 0,001. Se encontraron mejoras significativas en pacientes con cáncer de mama y de próstata (p < 0,05. El ejercicio es una intervención segura y eficaz en el control de la fatiga en pacientes sometidos a tratamiento activo

  7. Desempenho profissional ou doméstico das pacientes em quimioterapia para câncer de mama Professional or household performance of patients with breast cancer undergoing chemotherapy

    Directory of Open Access Journals (Sweden)

    Lourdes Conceição Martins

    2009-01-01

    Full Text Available OBJETIVOS: Analisar os aspectos epidemiológicos, clínicos, desempenho profissional e doméstico nas pacientes com câncer de mama em tratamento quimioterápico. MÉTODOS: O estudo foi transversal, com 52 mulheres entrevistadas, divididas em dois grupos: afastadas e não afastadas das atividades profissionais e domésticas, durante o tratamento com quimioterapia para câncer de mama. As pacientes foram provenientes de dois hospitais, um situado no município de Santo André e o outro no município de São Bernardo do Campo. Ambos são hospitais públicos de referência, que atendem a população de Santo André, São Bernardo do Campo, São Caetano do Sul, Diadema e Mauá, que são municípios vizinhos, pertencentes ao Estado de São Paulo, próximos da capital. Utilizou-se o questionário WPAI-GH (Work Productitity and Actitity Impairment para avaliar a atividade profissional e/ou doméstica das pacientes. RESULTADOS: As pacientes tinham idade média de 55,7 anos (dp=13,8, a maior parte de etnia branca (88,5%, casada (55,8%, assalariada (65,3% e a maioria se afastou das atividades (51,0%, com estadiamento da doença mais avançado (pOBJECTIVES: Evaluate patients with breast cancer undergoing chemotherapy with respect to their epidemiologic and clinical variables as well as performance at work or at home. METHODS: this was a cross-sectional study including 52 women interviewed during breast cancer chemotherapy, stratified in two groups: those who continued to work and do household tasks, and did not continue to work or do household tasks. Patients were from two public hospitals in the State of São Paulo, one in Santo Andre and the other in São Bernardo do Campo. The WPAI - GH (Work Productivity and Activity Impairment questionnaire was used to evaluate work and household performance of professionals or housewives, respectively. RESULTS: Mean age of the patients was 55.7 (SD=13.8, most were Caucasian (88.5%, married (55.8%, employed (65.3% and

  8. Antibioticoterapia oral versus endovenosa em crianças neutropênicas febris recebendo quimioterapia Oral vs. intravenous empirical antimicrobial therapy in febrile neutropenic patients receiving childhood cancer chemotherapy

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    Ângela Rech Cagol

    2009-12-01

    Full Text Available OBJETIVO: Comparar o uso de antibioticoterapia endovenosa versus oral. MÉTODOS: Foram selecionadas todas as crianças e adolescentes neutropênicos com idade inferior a 18 anos classificados como baixo risco para complicações e recebendo quimioterapia. O estudo ocorreu entre 2002 e 2005 na Unidade de Oncologia Pediátrica, Hospital de Clínicas de Porto Alegre, Porto Alegre (RS. Os pacientes, divididos em grupo A e grupo B, eram randomizados para receber terapia oral ou endovenosa. O tratamento utilizado para o grupo A foi ciprofloxacina e amoxicilina/clavulanato via oral e placebo endovenoso e, para o grupo B, cefepime e placebo oral. RESULTADOS: Foram selecionados 91 episódios consecutivos de neutropenia febril em 58 crianças. Para os pacientes do grupo A, a taxa de falência foi de 51,2% e a média de tempo de hospitalização foi de 8 dias (variação de 2-10. Para os pacientes tratados com antibioticoterapia endovenosa, a taxa de falência foi de 45,8% e a média de tempo de hospitalização foi de 7 dias (variação de 3-10. CONCLUSÃO: Neste estudo não houve diferenças entre a antibioticoterapia oral versus a terapia endovenosa. Estudos randomizados com maior número de pacientes são necessários antes de padronizar a terapêutica oral como tratamento para esta população de pacientes.OBJECTIVE: To compare the use of intravenous vs. oral antibiotic therapy. METHODS: All febrile neutropenic patients younger than 18 years old with low risk of complications and receiving chemotherapy were selected. The study was conducted from 2002 to 2005 at the Pediatric Oncology Unit of Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Patients were divided into group A and group B and were randomly assigned to receive oral or intravenous therapy. The empirical antimicrobial treatment used for group A consisted in oral ciprofloxacin plus amoxicillin-clavulanate and intravenous placebo, and group B received cefepime and oral placebo

  9. Artroplastía de superficie en cadera. Resultados iniciales favorables en pacientes selectos. [Hip resurfacing arthroplasty: favorable initial results in selected patients

    OpenAIRE

    Fernando Martín Comba; Gerardo Zanotti; Martín Buttaro; Francisco Piccaluga

    2013-01-01

    In­tro­duc­ción El objetivo del presente trabajo es reportar los resultados clínicos y radiológicos iniciales de una serie consecutiva de pacientes selectos tratados en nuestra institución con un único diseño de artroplastia de superficie, comparando además la tasa de revisión temprana con un grupo control de pacientes tratados en el mismo lapso con una artroplastia total de cadera no cementada. Material y ­Métodos Cuarenta y siete pacientes de sexo masculino (49 caderas) con diag...

  10. preescolares desnutridos con madres con obesidad y sin obesidad

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    Viridiana Vanessa Conzuelo-González

    2009-01-01

    Full Text Available El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estudio transversal (2006-2007, en la comunidad mazahua de San Francisco Tepeolulco, Municipio de Temascalcingo; que incluyó a 85 hogares integrados por preescolares con desnutrición inscritos al programa Oportunidades. Se determinó el estado nutrición de los preescolares con indicadores antropométricos y se obtuvo el IMC de las madres de estos infantes. Se aplicó una encuesta socionutricional, incluida el recordatorio de 24 horas, y complementado con la observación participante (cualitativa. Se encontró que 83% de las madres mazahuas presentaron sobrepeso u obesidad. El estado de nutrición de los preescolares con madres con obesidad presentó un porcentaje mayor de desnutrición (76%. En la variable género, se encontró que 54% de los niños con madres con obesidad tenía baja talla. Al relacionar el nivel educativo de la madre, esta variable resultó ser estadísticamente significativa (p=0.015, donde el analfabetismo está más relacionado con la desnutrición infantil que tienen madres de bajo y/o peso normal. La elevada prevalencia de hogares conformados con preescolares con desnutrición y madres con obesidad, es un síntoma más de la pobreza en zonas indígenas en México, con bajo índice de desarrollo humano.

  11. 45 CFR 73.735-502 - Permissible acceptance of gifts, entertainment, and favors.

    Science.gov (United States)

    2010-10-01

    ... acceptance of gifts, entertainment, and favors. (a) An employee may accept a gift, gratuity, favor, entertainment, loan or similar favor of monetary value which stems from a family relationship such as that between the employee and his or her parents, spouse or children, if it is clear that the relationship is...

  12. A Favorable Course of Palliative Sedation: Searching for Indicators Using Caregivers' Perspectives

    NARCIS (Netherlands)

    Brinkkemper, T.; Rietjens, J.A.C.; Deliens, L.; Ribbe, M.W.; Swart, S.J.; Loer, S.A.; Zuurmond, W.W.A.; Perez, R.S.G.M.

    2015-01-01

    Objective:Comparing characteristics of a favorable sedation course during palliative sedation to a less favorable course based on the reports Dutch physicians and nurses.Results:Cases identified as having a favorable sedation course less often concerned a male patient (P = .019 nurses' cases),

  13. Qualidade de vida de pacientes com câncer colorretal em terapia adjuvante Calidad de vida de pacientes con cáncer de rectocolon en terapia adyuvante Quality of life of patients with colorectal cancer who were receiving complementary therapy

    Directory of Open Access Journals (Sweden)

    Adriana Cristina Nicolussi

    2009-01-01

    Full Text Available OBJETIVO: Avaliar a qualidade de vida, identificar os domínios afetados nos pacientes com câncer colorretal, caracterizar os dados sócio-demográficos, clínicos e terapêuticos e correlacioná-los aos domínios da qualidade de vida. MÉTODOS: Estudo transversal, realizado no Centro Especializado de Oncologia de Ribeirão Preto com 22 pacientes com câncer colorretal em terapia adjuvante, entre julho/ 2006 a setembro/ 2007. Utilizou-se o instrumento Quality of Life Core-30-Questionnaire. RESULTADOS: A qualidade de vida foi considerada satisfatória (média = 79,13. Os domínios mais afetados foram: Função Emocional e sintomas dor, insônia, fadiga. Nas correlações, as mulheres destacaram-se negativamente, apresentando piores escores nas Funções Emocional, Cognitiva e sintomas: dor, insônia, fadiga, constipação e perda de apetite. Os pacientes em radioterapia relataram mais dor e os assintomáticos à quimioterapia são os que obtiveram melhor qualidade de vida geral. CONCLUSÃO: A qualidade de vida foi satisfatória, relativamente pior nas mulheres, em radioterapia e que apresentaram efeitos colaterais da quimioterapia.OBJETIVO: Evaluar la calidad de vida, identificar los dominios afectados en los pacientes con cáncer de rectocolon, caracterizar los datos socio-demográficos, clínicos y terapéuticos y correlacionarlos a los dominios de la calidad de vida. MÉTODOS: Estudio transversal, realizado en el Centro Especializado de Oncología de Ribeirão Preto con 22 pacientes con cáncer de rectocolon en terapia adyuvante, entre julio/ 2006 a setiembre/ 2007. Se utilizó el instrumento Quality of Life Core-30-Questionnaire. RESULTADOS: La calidad de vida fue considerada satisfactoria (media = 79,13. Los dominios más afectados fueron: Función Emocional y síntomas dolor, insomnio, fatiga. En las correlaciones, las mujeres se destacaron negativamente, presentando peores escores en las Funciones Emocional, Cognitiva y síntomas: dolor

  14. The use of religious/spiritual coping among patients with cancer undergoing chemotherapy treatment La utilización del enfrentamiento religioso/espiritual por pacientes con cáncer en tratamiento quimioterápico A utilização do enfrentamento religioso/espiritual por pacientes com câncer em tratamento quimioterápico

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    Ana Cláudia Mesquita

    2013-04-01

    Full Text Available OBJECTIVE: to investigate the use of religious/spiritual coping among people with cancer undergoing chemotherapy. METHODS: a quantitative, descriptive and cross-sectional study of 101 patients undergoing intravenous chemotherapy in an oncology outpatients center in a public hospital in Minas Gerais, made in the first semester of 2011. For data collection, an interview was held, using a questionnaire for characterizing the sample and the Brief Spiritual/Religious Coping Scale. RESULTS: all subjects made use of religious/spiritual coping (mean=3.67; sd=0.37; the younger individuals, those with no religion and those who consider spiritual support unimportant tend to use coping negatively; individuals who would like to receive spiritual support and who participate in support groups for cancer patients, on the other hand, use coping positively. CONCLUSIONS: the study reinforces that religious/spiritual coping is an important strategy for coping with cancer, and contributes to an understanding of the same as a useful tool for spiritual care. OBJETIVO: investigar el uso del enfrentamiento religioso/espiritual por personas con cáncer en quimioterapia. MÉTODOS: estudio cuantitativo, descriptivo y transversal, con 101 pacientes en quimioterapia endovenosa en un ambulatorio de oncología de un hospital público de Minas Gerais, desarrollado en el primero semestre del 2011. Para recolectar los datos, fueron utilizadas entrevistas, aplicándose un cuestionario para caracterizar la muestra y la Escala de Coping Religioso/Espiritual Abreviada. RESULTADOS: todos los sujetos utilizaron el coping religioso/espiritual (promedio=3,67; de=0,37; los individuos más jóvenes, sin religión y que no consideran importante el apoyo espiritual tienden a utilizar el coping de manera negativa; mientras los individuos a quienes les gustaría recibir apoyo espiritual y que participan de un grupo de apoyo al paciente con cáncer utilizan el coping de manera positiva

  15. autorregulado con estudiantes universitarios

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    Jairo Andrés Montes

    2005-01-01

    Full Text Available El propósito del presente estudio es describir la forma en la que se presentan los procesos de aprendizaje autorregulado con un grupo de estudiantes (22 estudiantes de tercer semestre de Psicología de la PUJ, Cali, en el evento de preparación para la presentación un examen. Asimismo se describen las correlaciones que ocurren entre las distintas fases de dicho proceso de autorregulación del aprendizaje. Para conseguir los objetivos propuestos se ha hecho uso de una observación de desempeño en tiempo real, es decir, de la observación durante una sesión de preparación de examen de los estudiantes, en la cual se emplearon protocolos verbales para dar cuenta de lo que «pasaba por su mente» mientras estudiaban. Una entrevista semi-estructurada y una prueba objetiva. Los resultados fueron analizados a la luz del modelo mixto de procesamiento de información y constructivismo abordado por Winne(1998. Como resultado se encontró una relación significativa entre los niveles de desempeño en el proceso de ARR y el resultado del examen. Igualmente se encontraron bajos niveles de regulación en una parte importante de la muestra y un desfase significativo entre conocimiento declarativo de ARR y desempeño en el mismo

  16. Puentes con vigas pretensadas

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    Editorial, Equipo

    1965-07-01

    Full Text Available This paper describes one of the three bridges which Hidrocivil, S. A., has built in Catalonia (northern Spain, over the river Ripoll. The other two bridges are very similar to this one, both in construction and design, and show only minor adjustments to the local topography. The contracting firm proposed several alterations in the prefabrication and constructional procedure, in relation to the initial project, and these changes were accepted. The main feature of these projects is the use of prestressed beams, built at the workshop in sections, and joined together by means of sixty 7 mm cables in each beam. As the shear forces are more acute at the joints, the end of each section has a kind of diaphragm, to provide a large contact area, and hence greater surface to transmit the shear forces. The methods of construction are also of interest. Briefly, they involve building the bridge piles, and use these to support a provisional structure with transversal movement. This provisional structure, in turn, served as platform for two bridge cranes, which lifted the girders to their final location. After the first span was completed, the deck was concreted and the auxiliary structure pushed forward to the next span, to repeat the same operations. This arrangement saved the use of provisional framework.En este trabajo se describe uno de los tres puentes que Hidrocivil, S. A., ha construido.—previo concurso— en la región catalana; concretamente, el que salva el río Ripoll. Los otros dos no han sido objeto de descripción general por ser muy similares, en lo que a ejecución y concepción se refiere, con la única variante que presentan las características topográficas locales. La empresa propuso ciertas variantes— que fueron aceptadas— en la prefabricación y métodos de construcción. El interés de estas obras se centra en el empleo de vigas pretensadas, prefabricadas en taller por trozos, y solidarizados en el mismo mediante las operaciones

  17. Violencia con el anciano

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    Rita Campillo Motilva

    2002-08-01

    Full Text Available La violencia doméstica es tan antigua como la humanidad misma y se reconocen la violencia infantil, contra la mujer y al anciano, fundamentalmente; siendo este último grupo una población en ascenso por las mayores expectativas de vida de los últimos años. Como resultado de ello, el número de casos de abuso en el anciano se incrementará y el impacto de este abuso sobre la salud debe ser considerado de forma adecuada. La gama de maltratos es variadísima e incluye el abuso físico, emocional, financiero, sexual, por negligencia, negación a brindarle ayuda y otras formas más. Los ancianos con deterioro cognitivo son los más vulnerables. El médico en la atención primaria de salud es un pilar importante en la prevención y educación de este problema.Domestic violence is as old as humanity itself. Child, women and elderly abuse are mainly recognized. The elderly group is increasing due to the higher life expectancy experimented during the last years. As a result, the number of battered elderly will grow and the impact of this abuse on health should be adequately considered. The range of abuse is very wide and it includes physical, emotional, financial and sexual abuse, negligence, rejection to give assistance and others. The elderly with cognitive deterioration are the most vulnerable. The physician at the primary health care level is an important milestone in the prevention and education of this problem.

  18. Evaluación de la seguridad del nimotuzumab en pacientes con cáncer de pulmón de células no pequeñas portadores de metástasis cerebral

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    Nadia Aguilera Calvo

    2015-06-01

    Full Text Available Fundamento: nimotuzumab es un novedoso anticuerpo monoclonal humanizado, con efecto antitumoral, que reconoce el receptor del factor de crecimiento epidérmico sobrexpresado en muchos tumores malignos de origen epitelial, como: esófago, pulmón, glioblastoma multiforme y próstata. Es usado en combinación con las terapias oncoespecificas, como quimioterapia o radiosensibilizador. Hasta la fecha se han tratado más de 2000 pacientes con este producto, además, es el primer anticuerpo monoclonal registrado en el país para pacientes pediátricos. Objetivo: describir los eventos adversos asociados con el nimotuzumab en pacientes con cáncer de pulmón de células no pequeñas portadores de metástasis cerebral incluidos en un ensayo clínico. Métodos: se analizaron las características de base de los pacientes, así como la frecuencia, intensidad y relación de causalidad de los eventos reportados. La población de estudio la conformaron todos los pacientes incluidos en el ensayo clínico. Resultados: la mayoría de los eventos fueron de intensidad leve a moderada y no requirieron la suspensión del tratamiento. Los eventos adversos más frecuentes fueron: astenia, anorexia, cefalea y vértigos; efectos reportados en estudios previos. Conclusiones: nimotuzumab es un fármaco seguro para el tratamiento de pacientes aquejados de cáncer de pulmón de células no pequeñas y metástasis cerebral.

  19. Tratamiento ambulatorio del paciente con neutropenia febril Outpatient therapy in patients with febrile neutropenia

    Directory of Open Access Journals (Sweden)

    Andrés Londoño Gallo

    2008-01-01

    Full Text Available

    El tratamiento de los pacientes con neoplasia y neutropenia febril plantea muchas dudas. Una de ellas, que genera ansiedad en el personal de la salud, el paciente y sus familiares, es la necesidad de hospitalización porque ésta implica exponer a gérmenes intrahospitalarios potencialmente resistentes a un paciente cuyo sistema inmune puede no estar en las mejores condiciones; incluso con un aislamiento óptimo existe el riesgo de adquirir una infección nosocomial. Muchos estudios han tratado de validar métodos para clasificar a los pacientes con fiebre y neutropenia en grupos de diferente riesgo, como fundamento para implementar estrategias de tratamiento selectivo; así se ha abierto la posibilidad de utilizar medidas más conservadoras para el tratamiento de los episodios de bajo riesgo, entre ellas la administración de regímenes orales ambulatorios de antibióticos de amplio espectro; ello sin demeritar la necesidad de aplicar un juicio clínico adecuado, hacer un buen seguimiento y tener acceso a la atención médica inmediata. La neutropenia es una de las consecuencias graves de la quimioterapia para el cáncer, y se ha demostrado que el tratamiento del paciente neutropénico febril con antibióticos intravenosos reduce la mortalidad. La terapia oral podría ser una alternativa aceptable para pacientes bien seleccionados. Ella puede mejorar la calidad de vida de los pacientes con cáncer, evitar las complicaciones asociadas con la terapia intravenosa y disminuir los costos del tratamiento.

    Treatment of patients with neoplasia and febrile neutropenia, as a consequence of chemotherapy, poses many doubts, among them the need for hospitalization, since this implies exposure to potentially resistant nosocomial microorganisms. Even under the best isolation techniques, there may

  20. A favorable course of palliative sedation: searching for indicators using caregivers' perspectives.

    Science.gov (United States)

    Brinkkemper, Tijn; Rietjens, Judith A C; Deliens, Luc; Ribbe, Miel W; Swart, Siebe J; Loer, Stephan A; Zuurmond, Wouter W A; Perez, Roberto S G M

    2015-03-01

    Comparing characteristics of a favorable sedation course during palliative sedation to a less favorable course based on the reports Dutch physicians and nurses. Cases identified as having a favorable sedation course less often concerned a male patient (P = .019 nurses' cases), reached the intended sedation depth significantly quicker (P sedation (P = .015 physicians' cases), and had a shorter total duration of sedation compared (P sedation course. A favorable course during palliative sedation seems more probable when health care professionals report on a (relatively) shorter time to reach the required depth of sedation and when a deeper level of sedation can be obtained. © The Author(s) 2013.

  1. Acne polimorfo: tratamiento con Implacen

    Directory of Open Access Journals (Sweden)

    Rubén Pérez Armas

    1995-06-01

    Full Text Available Se realiza el estudio de 40 pacientes con acné polimorfo, los que fueron atendidos en la Consulta de Dermatología del Hospital Provincial Clinicoquirúrgico Docente "Celia Sánchez Manduley", en el período comprendido de enero de 1988 a diciembre de 1989. Se revisa la literatura médica sobre los diversos métodos y medicamentos utilizados en la terapéutica de esta dermatosis. Se describe el esquema de tratamiento empleado con implacén en 30 pacientes; los 10 restantes se trataron con placebo; se compara dicho esquema con los tradicionales y se observan mejores resultados con nuestro estudio. Se destaca la ausencia de recaídas, así como el resultado del tratamiento de acuerdo con el sexo.A study was performed in 40 patients presenting with polymorphic acne who were attended in the Dermatology Department of "Celia Sánchez Manduley" Clinicosurgical and Teaching Hospital from January, 1988 to December, 1989. A review of the literature was made seeking for the different methods and drugs used for the treatment of this dermatosis. The treatment schedule with the use of implacen in 30 patients is described. Such therapeutic schedule was compared with traditional ones and better results were observed with the use of implacen. The fact that there were no relapses is highlighted, as well as the result of treatment according to sex.

  2. «En favor de las víctimas de la guerra»

    Directory of Open Access Journals (Sweden)

    Robles Muñoz, Cristóbal

    2009-12-01

    Full Text Available Informal representation given to Cardinal Gomá in December 1936, sending Ildebrando Antoniutti as apostolic delegate in humanitarian mission in July, remained at its lowest level relations between the Holy See with the government of Franco. The situation changed in 1937. The nuncio Gaetano Cicognani did not arrive until June 1938. Discrete steps of a secret diplomacy advised in September 1937 to formalize the relationship, at its lowest. Antoniutti and Pablo de Churruca were named Responsible of Affairs, in Burgos, and to the Holy See, in a respective way. The collective letter of the bishops helped to improve the image of «national» Spain before the Catholics in other countries. The doctrinal position in which these facts were inserted was fixed at three encyclicals published in March 1937. They condemned the religious persecution of communism, nazism and the fear of a desire to runaway of the persecution forgiving people and fighting for justice for the working classesLa representación oficiosa dada al cardenal Gomá en diciembre de 1936, el envío Ildebrando Antoniutti como delegado apostólico en julio en misión humanitaria, mantuvieron bajo mínimos las relaciones de la Santa Sede con el Gobierno de Franco. La situación no cambió en 1937. El nuncio Gaetano Cicognani no llegó hasta junio de 1938. Los pasos discretos de una diplomacia secreta aconsejaron en septiembre de 1937 formalizar las relaciones, en su nivel más bajo. Antoniutti y Pablo de Churruca fueron nombrados encargados de negocios, en Burgos y ante la Santa Sede. La carta colectiva de los obispos ayudó a mejorar la imagen los nacionales ante los católicos de otros países. La posición doctrinal en que se insertan estos hechos quedó fijada en las tres encíclicas publicadas en marzo de 1937. En ella se denuncia la persecución religiosa del comunismo, el temor al nazismo y el deseo de salir de la persecución personando y luchando por la justicia a favor de las clases

  3. con mala calidad de vida

    Directory of Open Access Journals (Sweden)

    Agustín Martín-Rodríguez

    2007-01-01

    Full Text Available En este estudio ex post facto se ha analizado si los familiares de pacientes con mala calidad de vida presentan diferencias en las variables clínicas de personalidad y relaciones familiares en función de que el paciente haya estado o no ingresado en una Unidad de Cuidados Intensivos. Seleccionamos dos grupos: 29 familiares de pacientes traumatizados graves transcurridos cuatro años de su ingreso en una UCI de Traumatología y con mala calidad de vida (debido a secuelas físicas y/o psicológicas tras el ingreso, tales como traumatismos craneoencefálicos, politraumatismos y tetraplejias traumáticas y 32 familiares de pacientes con mala calidad de vida con cuatro años de evolución de su enfermedad física (hipertensión, diabetes, artritis reumatoide y síndrome de intestino irritable que no han estado ingresados en la UCI. Para alcanzar nuestro objetivo empleamos una Encuesta Psicosocial y los siguientes instrumentos: Cuestionario de Análisis Clínico, Escala de Clima Social en la Familia y Escala de Adaptación Psicosocial de la Enfermedad. Los resultados mostraron que los familiares de pacientes con mala calidad de vida que estuvieron ingresados en la UCI hace cuatro años, presentan diferencias significativas en las variables agitación y expresividad comparados con los familiares de pacientes con mala calidad de vida que no han estado ingresados en la UCI.

  4. Expansión cutánea externa con endermología: un método alternativo complementario en reconstrucción mamaria diferida

    Directory of Open Access Journals (Sweden)

    M. De la Cruz

    2015-12-01

    Full Text Available Con el objetivo de mejorar las técnicas de reconstrucción mamaria diferida, incorporamos la técnica de endermología como método de expansión cutánea externa para eliminar el plano cicatricial inextensible que se forma entre la fascia del pectoral y el tejido celular subcutáneo tras la cirugía radical. Se trata de un procedimiento sencillo, de bajo coste y de aplicación universal, que en estos casos enfocamos a evitar nuevas cicatrices, complicaciones de zonas donantes, ingresos hospitalarios prolongados y los riesgos quirúrgicos elevados propios de las técnicas de reconstrucción mamaria con colgajos libres o pediculados, así como los frecuentes resultados insatisfactorios de la reconstrucción con expansor y prótesis en pacientes radiadas. Cuando la piel presenta un grosor insuficiente o la paciente ha sido sometida a radioterapia previa, complementamos el tratamiento con lipotransferencia de grasa abdominal. Todos los tratamientos de expansión cutánea externa se realizan en consulta mediante un equipo Cellu m6 (LPG® endermologia, Francia. Tras la expansión, realizamos la reconstrucción como un aumento mamario simple con prótesis anatómica. Medimos la ganancia de elasticidad cutánea tras masaje y el grosor dermograso mediante test de pellizco. Realizamos la simetrización de la mama contralateral ptósica o hipertrófica en el momento de la colocación del implante o de la mastectomía subcutánea contralateral profiláctica en pacientes de riesgo. Incluimos en el estudio mujeres sin distinción de edad, tipo o tamaño de tumor, o si han recibido radio o quimioterapia. Con esta técnica, obtenemos resultados homogeneamente satisfactorios sin añadir nuevas cicatrices y mejorando la calidad de la piel y de la cicatriz de mastectomía.

  5. Disfunción neurocognitiva en niños con leucemia linfoide aguda Neurocognitive disfunction in children with acute lymphoid leukemia

    Directory of Open Access Journals (Sweden)

    Raúl Martínez-Triana

    2013-03-01

    Full Text Available Introducción: se ha comunicado afectación neurocognitiva como secuela a largo plazo en pacientes curados de leucemia linfoide aguda que fueron irradiados durante el tratamiento. Más recientemente esto se plantea también para los tratados solo con quimioterapia. Sobre estos últimos no se conocen antecedentes en Cuba de estudios de este tipo. Métodos: se estudió el rendimiento intelectual de 77 pacientes entre 6 y 32 años (54 con tratamiento y 23 con sobrevida de más de 5 años que no recibieron radiaciones durante su tratamiento, y de un grupo (n=20 de adolescentes sanos. Se utilizó la escala de inteligencia de Wechsler para niños (Wisc y para adultos (Wais. Resultados: los resultados mostraron que las escalas totales, tanto de los enfermos como de los curados, se encontraba dentro de parámetros normales. Sin embargo, se obtuvieron notaciones significativamente más bajas en los pacientes curados que en los sanos en las pruebas de semejanzas, dígitos, ordenar figuras y diseño de bloques; también en el factor de distractibilidad. Los pacientes que se encontraban enfermos en la evaluación obtuvieron puntuación más baja que los normales solo en la prueba de dígitos. Conclusiones: estos resultados sugieren afectaciones subclínicas específicas relacionadas con la capacidad de asociación de conceptos verbales, memoria inmediata, capacidad de planeamiento estratégico, organización visoespacial, análisis y síntesis como procesos del pensamiento, así como una dificultad atencional en los pacientes curados como secuela de la quimioterapia.Introduction: neurocognitive disorders have been reported as long-term side effects in patients free from acute lymphoid leukemia that had undergone radiotherapy. These disorders have been likewise reported in those cases in which the patients had undergone chemotherapy. No antecedents about previous study on the latter in Cuba are known. Methods: the intellectual performance of 77 patients who

  6. Estudio comparativo del efecto del cepillado con una crema dental con propóleos rojos y de un gel con clorofila

    Directory of Open Access Journals (Sweden)

    Estela Gispert Abreu

    1998-12-01

    Full Text Available Se analiza comparativamente el efecto de un gel dental de clorofila y de una crema dental con propóleos rojos sobre varios parámetros relacionados con la caries dental, en escolares que se cepillaron durante 21 días con dichos productos. Se obtuvieron resultados favorables principalmente en la disminución del grado de infección por Streptococcus mutans y la elevación de la capacidad individual de remineralización; salvo en este último no hubo diferencias estadísticamente significativas.Authors made a comparative analysis about effect of chlorophyl dental gel and toothpaste containing red propolis, on some parameters related to dental caries in a group of students that brushed their teeth during 21 days using such products. Favourable results were obtained, mainly in decrease of infection level from Streptococcus mutans, and in increase of individual capacity of remineralization; except for this latter, there weren´t statistically significant differences.

  7. CALIDAD DE VIDA RELACIONADA CON LA SALUD EN PACIENTES CON LUPUS ERITEMATOSO SISTÉMICO Y SU RELACIÓN CON DEPRESIÓN, ANSIEDAD Y OPTIMISMO DISPOSICIONAL.

    Directory of Open Access Journals (Sweden)

    Juan Manuel Anaya

    2006-06-01

    Full Text Available La siguiente investigación presenta los resultados de un estudio desarrollado en Colombia sobre la evaluación de la calidad de vida y sus relaciones con la depresión, ansiedad y optimismo disposicional en 32 pacientes con diagnóstico de lupus eritematoso sistémico de la Clínica Universitaria Bolivariana de la ciudad de Medellín, Colombia. Para evaluar la calidad de vida se utilizó el Cuestionario SF36, la ansiedaddepresión fue evaluada mediante el Cuestionario HAD, y se trabajó con el Cuestionario DIOP para medir optimismo. El estudio evidenció que los pacientes perciben una calidad de vida favorable en todas las dimensiones que conforman el cuestionario SF36, no se encontraron niveles clínicamente significativos de ansiedad-depresión, y por último se encontró alta predisposición hacia el optimismo.

  8. Tratamiento con implantes Leader-Nano en paciente con oligodoncia

    Directory of Open Access Journals (Sweden)

    Salvador Javier Santos Medina

    2015-03-01

    Full Text Available Los implantes dentales de titanio han revolucionado el mundo de la rehabilitación desde su surgimiento. De manera particular, el empleo de implantes de carga inmediata acorta el tiempo quirúrgico y protésico, con el consiguiente bienestar estético. Se presenta el caso de una paciente femenina de 32 años de edad, con antecedentes de oligodoncia de ambos incisivos laterales superiores y portadora de prótesis parcial acrílica. Fue atendida por el equipo multidisciplinario de implantes en la Clínica Estomatológica Docente “3 de Octubre” y se le realizó tratamiento de rehabilitación integral con implantes Leader-Nano y prótesis fija con corona acrílica sobre dichos implantes. La implantología fue satisfactoria en la paciente; la mejoría estética y funcional, así como la satisfacción de la paciente, fueron los principales logros obtenidos

  9. Alcances y dimensiones del plagio en la narrativa de Alberto Laiseca: alrededor de Por favor ¡plágienme!

    Directory of Open Access Journals (Sweden)

    Carlos Fernández González

    2014-11-01

    Full Text Available A través de la lectura crítica de Por Favor ¡Plágienme! (1991, texto clave para la comprensión del universo estético y creativo de Alberto Laiseca, este artículo plantea reflexiones sobre el enfoque singular que su obra narrativa aporta al problema del plagio en la literatura contemporánea y postula, al mismo tiempo, la posibilidad de pensar la obra de Laiseca en tensa –y paródica– relación con la tradición literaria argentina y su canon. Esta lectura permitirá operar críticamente sobre el dispositivo central de la literatura laisecana, que consiste en desestabilizar los discursos teóricos disponibles sobre aspectos aplicables a su poética, como el del horizonte conceptual del plagio. Desde aquí se volverá posible pensar en los motivos por los cuales una crítica literaria hegemónica tiene hasta el momento poco diálogo con la obra de quien es, sin embargo, uno de los autores contemporáneos más prolíficos de la literatura argentina. Through the critical reading of Por Favor ¡Plágienme! (1991, a key text for understanding the aesthetic and creative universe of Alberto Laiseca, this article enquires into the unique approach that his narrative opens to the issue of plagiarism in contemporary literature. The article also postulates thinking Laiseca’s work in a tense –and parodic– relationship with the Argentinian literary tradition and its canon. This reading will operate on the central device of “Laisecan” literature, which consists on destabilizing available theoretical discourses over aspects that can be applied to his poetics, as the conceptual horizon of plagiarism. From here it will be possible to consider why a hegemonic literary criticism has had little dialogue with the work of someone who is, however, one of the most prolific contemporary writers of Argentinian literature.

  10. con dietas suplementadas con Cromo-L-metionina

    Directory of Open Access Journals (Sweden)

    Ram\\u00F3n Garc\\u00EDa-Castillo

    2006-01-01

    Full Text Available Un total de 48 cerdos (Sus scrofa domesticus; 24 machos castrados y 24 hembras cruzados (Yorkshire, Hampshire, Duroc y Landrace de 3,5 a 4,0 meses de edad y 60,0 ± 5,0 kg PV en finalización. Se alimentaron con dietas isoproteícas (14,5 % PC e isoenergéticas (3.400 kcal EM/kg de MS, adicionadas con Cr-L-metionina (MiCroPlex® (0, 200, 400 y 600 ppb. El experimento tuvo una duración de 45 días y se realizó de agosto a noviembre del 2002 en las instalaciones de la Universidad Autónoma Agraria Antonio Narro, localizada en Saltillo, Coahuila, México. Al tener los animales aproximadamente 95 kg PV, se tomó muestra de 15 ml de sangre por cada animal para determinar la concentración de glucosa, ácido úrico, creatinina, urea, proteinas totales y colesterol. Se aplicó un diseño completamente al azar con arreglo factorial 2 x 4; dos para el factor sexo y cuatro para nivel de cromo. Los metabolitos en suero no fueron afectados (P>0,05 por el factor sexo. La glucosa en suero disminuyó (P<0,05 y el colesterol incrementó (P<0,05 con cromo en la dieta. Se concluye que el Cr incrementa el metabolismo de glucosa y disminuye el de colesterol, con lo cual puede haber energía disponible para síntesis de proteína la cual es necesaria para el crecimiento de los animales

  11. A generalização a partir do tratamento com fricativas: ambientes favoráveis versus ambientes pouco favoráveis e neutros The generalization through the treatment with fricatives: favorable environments versus unfavorable and neutral environments

    Directory of Open Access Journals (Sweden)

    Fernanda Marafiga Wiethan

    2013-01-01

    Full Text Available O objetivo deste estudo foi analisar e comparar a ocorrência e os tipos de generalização observados a partir do tratamento das fricativas /z/, /ζ/ e /k/ em dois grupos de crianças, um utilizando palavras com contextos fonológicos favoráveis e outro os contextos pouco favoráveis e neutros. Seis crianças com desvio fonológico e idades entre 4:7 e 7:8 participaram do estudo com a autorização dos responsáveis. Realizaram-se avaliações fonoaudiológicas e complementares para o diagnóstico do desvio fonológico. Os sujeitos foram pareados de acordo com a gravidade do desvio, sexo, faixa etária e aspectos do sistema fonológico em relação aos fonemas alterados. Metade das crianças foi tratada com palavras em que os fonemas /z/, /ζ/ e /k/ encontravam-se em ambientes fonológicos favoráveis e a outra metade com ambientes pouco favoráveis e neutros. Foram realizadas oito sessões e, após estas, nova avaliação de fala foi realizada para verificar os tipos de generalização obtidos. Os percentuais de generalizações foram comparados entre os grupos por meio do teste estatístico de Mann-Whitney (pThe aim of this study was to analyze and compare the occurrence and the types of generalization observed through the treatment of the fricatives /z/, /ζ/ and /k/ in two groups of children, one using words with favorable phonological contexts and another with unfavorable and neutral contexts. Six children with phonological disorder between 4:7 and 7:8 year-old participated in the study, with their parents' authorization. There were speech-language and complementary evaluations to diagnose the phonological disorder. The subjects were matched according to the severity of the phonological disorder, sex, age and aspects of the phonological system in relation to the altered phonemes. Half the children were treated with words in which the phonemes /z/, /ζ/ and /k/ were in favorable phonological environments and the other half with unfavorable

  12. Preliminary evaluation of the uranium favorability in the area northeast of Gunnison, Colorado

    International Nuclear Information System (INIS)

    Gallagher, G.L.; Edmond, C.L.; D'Andrea, R.F. Jr.

    1977-08-01

    Rock and steam-sediment samples were collected to define areas favorable for uranium deposits northeast of Gunnison, Colorado. Areas considered most favorable for further exploration are: (1) the Bronco Mountain area, approximately 10 mi south of Taylor Park Reservoir, (2) the area near the Big Red mine, and (3) the area 5 mi north-northeast of Taylor Park Reservoir. On the basis of known deposits in the Marshall Pass and Cochetopa districts, fault contacts between Precambrian granites and Paleozoic or Mesozoic sedimentary rocks are favorable structural sites

  13. Resultados clínico-radiológicos en pacientes jóvenes con fractura articular completa de radio distal tratados con placa palmar bloqueada. [Clinical and radiological results in young patients with complete articular distal radius fractures treated with volar locked plate.

    Directory of Open Access Journals (Sweden)

    Pablo De Carli

    2016-02-01

    Conclusión: El tratamiento de las fracturas de radio distal tipo C en pacientes jóvenes con placa palmar bloqueada muestra resultados clínicos y radiológicos favorables con corrección de la mayoría de los escalones articulares.

  14. Prevention, Diagnosis and Treatment of Chemotherapy-Induced Cardiotoxicity: what Are we Doing about it? Prevención, diagnóstico y tratamiento de la cardiotoxicidad inducida por quimioterapia: ¿qué estamos haciendo?

    Directory of Open Access Journals (Sweden)

    Lázaro de la Cruz Avilés

    2012-11-01

    Full Text Available Heart disease and malignant tumors are the two leading causes of death in Cuba, with mortality rates of 197,5 and 193,6 per 100 000, respectively, in 2011. In Cienfuegos, malignant tumors were the leading cause of death with a rate of 115,2 followed by heart disease with 102,6 per 100 000 inhabitants. The improvements in the detection and treatment of cancer have led to a new cohort of patients achieving such a long survival that cardiac complications may appear. Unfortunately, the wide knowledge on biochemical pathways involved in cancer targeted therapy has not been accompanied by a parallel understanding of cardiac consequences of their modulation.Las enfermedades del corazón y los tumores malignos constituyen las dos primeras causas de muerte en Cuba, con tasas de mortalidad de 197,5 y 193,6 por 100 000 habitantes, respectivamente, en el año 2011. En Cienfuegos los tumores malignos fueron la primera causa de muerte con una tasa de 115,2 seguida de las enfermedades del corazón con 102,6 por 100 000 habitantes. Las mejoras alcanzadas en la detección y el tratamiento del cáncer han dado origen a una nueva cohorte de pacientes que alcanzan una supervivencia suficiente para que puedan aparecer complicaciones cardíacas derivadas del tratamiento. Lamentablemente, el abundante conocimiento sobre las vías bioquímicas involucradas en el tratamiento dirigido del cáncer no se ha visto acompañado de un conocimiento paralelo de las consecuencias cardíacas de su modulación.

  15. Recubrimiento de acero con polidopamina

    OpenAIRE

    Carrasco Rodríguez, Javier

    2013-01-01

    Se ha obtenido recubrimientos de polidopamina en acero mecánicamente resistentes y con tiempos de obtención relativamente pequeños a través de la polimerización de la dopamina bajo diferentes condiciones.

  16. Colesterol y triglicéridos como marcadores bioquímicos del estado de la enfermedad del paciente con leucemia linfocítica aguda

    Directory of Open Access Journals (Sweden)

    Marco Guzmán

    2004-12-01

    Full Text Available Objetivo: Determinar la relación de los niveles séricos de colesterol y triglicéridos con el estado de respuesta al tratamiento quimioterápico de inducción de pacientes con leucemia linfocítica aguda. Material y Métodos: La muestra la conforman 25 pacientes de 2 a 18 años de edad, admitidos al Instituto de Enfermedades Neoplásicas con un diagnóstico reciente de leucemia linfocítica aguda; determinándose en ellos sus concentraciones séricas de colesterol total, colesterol-HDL, colesterol-LDL y triglicéridos, antes y después de la primera fase de la quimioterapia de inducción. Resultados: Solamente 23 pacientes respondieron al tratamiento y en ellos observamos un incremento de 19,24 ± 4,49 mg/dL a 46,84 ± 15,38 mg/dL para el colesterol-HDL; y un descenso de 153,66 ± 36,39 mg/dL a 79,79 ± 34,53 mg/dL para los triglicéridos (p<0,0001. Por el contrario, en los pacientes que no respondieron al tratamiento, se obtuvo un incremento de 14,64 ± 2,46 mg/dL a 23,13 ± 14,23 mg/dL para el colesterol-HDL y un incremento de 121,88 ± 0,56 mg/dL a 161,01 ± 75,25 mg/dL para los triglicéridos. Conclusión: Las concentraciones séricas de colesterol y triglicéridos se relacionan con el estado de la enfermedad del paciente con leucemia linfocítica aguda. Proponemos a estos metabolitos, como marcadores bioquímicos en el seguimiento clínico de esta enfermedad.

  17. Major Deficiencies Preventing Favorable Audit Opinions on the FY 1997 DoD Financial Statements

    National Research Council Canada - National Science Library

    Lane, F

    1998-01-01

    The audit objective was to identify and summarize the major deficiencies that prevented favorable audit opinions on the FY 1997 DoD Financial Statements, and to identify the actions taken or under way...

  18. Uranium favorability of late Eocene through Pliocene rocks of the South Texas Coastal Plain

    Energy Technology Data Exchange (ETDEWEB)

    Quick, J.V.; Thomas, N.G.; Brogdon, L.D.; Jones, C.A.; Martin, T.S.

    1977-02-01

    The results of a subsurface uranium favorability study of Tertiary rocks (late Eocene through Pliocene) in the Coastal Plain of South Texas are given. In ascending order, these rock units include the Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand. The Vicksburg Group, Anahuac Formation, and Fleming Formation were not considered because they have unfavorable lithologies. The Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand contain sandstones that may be favorable uranium hosts under certain environmental and structural conditions. All except the Yegua are known to contain ore-grade uranium deposits. Yegua and Jackson sandstones are found in strand plain-barrier bar systems that are aligned parallel to depositional and structural strike. These sands grade into shelf muds on the east, and lagoonal sediments updip toward the west. The lagoonal sediments in the Jackson are interrupted by dip-aligned fluvial systems. In both units, favorable areas are found in the lagoonal sands and in sands on the updip side of the strand-plain system. Favorable areas are also found along the margins of fluvial systems in the Jackson. The Frio and Catahoula consist of extensive alluvial-plain deposits. Favorable areas for uranium deposits are found along the margins of the paleo-channels where favorable structural features and numerous optimum sands are present. The Oakville and Goliad Formations consist of extensive continental deposits of fluvial sandstones. In large areas, these fluvial sandstones are multistoried channel sandstones that form very thick sandstone sequences. Favorable areas are found along the margins of the channel sequences. In the Goliad, favorable areas are also found on the updip margin of strand-plain sandstones where there are several sandstones of optimum thickness.

  19. Uranium favorability of late Eocene through Pliocene rocks of the South Texas Coastal Plain

    International Nuclear Information System (INIS)

    Quick, J.V.; Thomas, N.G.; Brogdon, L.D.; Jones, C.A.; Martin, T.S.

    1977-02-01

    The results of a subsurface uranium favorability study of Tertiary rocks (late Eocene through Pliocene) in the Coastal Plain of South Texas are given. In ascending order, these rock units include the Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand. The Vicksburg Group, Anahuac Formation, and Fleming Formation were not considered because they have unfavorable lithologies. The Yegua Formation, Jackson Group, Frio Clay, Catahoula Tuff, Oakville Sandstone, and Goliad Sand contain sandstones that may be favorable uranium hosts under certain environmental and structural conditions. All except the Yegua are known to contain ore-grade uranium deposits. Yegua and Jackson sandstones are found in strand plain-barrier bar systems that are aligned parallel to depositional and structural strike. These sands grade into shelf muds on the east, and lagoonal sediments updip toward the west. The lagoonal sediments in the Jackson are interrupted by dip-aligned fluvial systems. In both units, favorable areas are found in the lagoonal sands and in sands on the updip side of the strand-plain system. Favorable areas are also found along the margins of fluvial systems in the Jackson. The Frio and Catahoula consist of extensive alluvial-plain deposits. Favorable areas for uranium deposits are found along the margins of the paleo-channels where favorable structural features and numerous optimum sands are present. The Oakville and Goliad Formations consist of extensive continental deposits of fluvial sandstones. In large areas, these fluvial sandstones are multistoried channel sandstones that form very thick sandstone sequences. Favorable areas are found along the margins of the channel sequences. In the Goliad, favorable areas are also found on the updip margin of strand-plain sandstones where there are several sandstones of optimum thickness

  20. Quimioterapia neoadjuvante seguida de cirurgia radical em paciente grávida com câncer de colo de útero: relato de caso e revisão de literatura Neoadjuvant chemotherapy followed by radical surgery in pregnant patient with invasive cervical cancer: case report and literature review

    Directory of Open Access Journals (Sweden)

    Allex Jardim da Fonseca

    2011-01-01

    Full Text Available Em pacientes grávidas portadoras de câncer de colo de útero (CCU, as opções terapêuticas dependem da idade gestacional, do estágio clínico e do desejo da paciente. Alguns autores relataram casos de quimioterapia neoadjuvante seguidos de cirurgia radical nessas pacientes. O objetivo deste artigo foi revisitar o assunto, adicionar um novo caso e revisar a literatura. Relatamos o caso de uma mulher de 30 anos, na 24ª semana de gestação, que teve diagnóstico de câncer de colo de útero (carcinoma escamoso grau II, estágio IIB (Federação Internacional de Ginecologia e Obstetrícia - FIGO. Nulípara, a paciente recusou a interrupção da gravidez. Após meticuloso esclarecimento, a paciente aceitou tratamento com quimioterapia neoadjuvante com cisplatina 75 mg/m² e vincristina 1 mg/m², além de posterior avaliação de cirurgia radical e parto cirúrgico concomitantes. Quatros ciclos completos de quimioterapia foram administrados sem atrasos ou efeitos adversos importantes. Poucos dias antes da data programada para a cirurgia, a paciente foi admitida em trabalho de parto na 37ª semana de gestação. Devido à resposta clínica completa do tumor, a equipe obstétrica optou por monitorar o trabalho de parto, e a paciente deu à luz um recém-nascido de 2.450 g, sem intercorrências. A cirurgia radical foi realizada três dias após o parto, e a análise histopatológica revelou carcinoma confinado ao colo sem envolvimento linfonodal. Mãe e filho se encontram em bom estado geral 12 meses após o parto. Quimioterapia baseada em cisplatina durante o segundo ou terceiro trimestre da gravidez parece ser uma opção para as pacientes que não desejam a interrupção da gravidez enquanto se aguarda a maturidade fetal. Entretanto, estudos adicionais são necessários para confirmar o prognóstico e a segurança dos recém-nascidos e das pacientes.The treatment options for pregnant patients with invasive cervical cancer (ICC depend on

  1. Santiago, una ciudad con temor

    Directory of Open Access Journals (Sweden)

    Enrique Oviedo S.

    1999-04-01

    Full Text Available El objetivo general de este artículo es evaluar los efectos de la inseguridad ciudadana en el uso del espacio público. Dicha evaluación exige analizar dos relaciones que se establecen en el ámbito de la violencia: la relación entre victimización y percepción de inseguridad; y la que se establece entre actitudes sociales y resolución pacífica de conflictos nacionales. Para ello, se analizaron las variables victimización, percepción de inseguridad, uso del espacio físico, actitudes hacia el sistema institucional político y social y hacia la resolución de conflictos nacionales, y las posibles relaciones entre ellas. Los datos para realizar el estudio se obtuvieron por medio de una encuesta que se llevó a cabo con 1 200 personas de 18 y 70 años de edad residentes en la ciudad de Santiago. Los resultados indican que Santiago es una ciudad de habitantes con temor y que el aumento de la percepción de inseguridad de sus habitantes contrasta con el hecho de que las tasas de victimización se hayan mantenido, más o menos, constantes en los años que precedieron a la encuesta. El temor se relaciona con el abandono del espacio público físico y sociopolítico, así como con el refugio en los espacios y la vida privados. La actitud de resolver los conflictos por medios no pacíficos es frecuente y se asocia en mayor medida con la inseguridad, la actitud negativa hacia la democracia y la falta de expectativas sobre el futuro del país. Los resultados de este estudio respaldan la idea de que para superar el temor la gente tiende a adaptarse a la realidad adoptando una postura conformista, homogeneizando las creencias y los comportamientos, y sobreestimando la fuerza como medio para resolver las diferencias.

  2. Santiago, una ciudad con temor

    Directory of Open Access Journals (Sweden)

    Oviedo S. Enrique

    1999-01-01

    Full Text Available El objetivo general de este artículo es evaluar los efectos de la inseguridad ciudadana en el uso del espacio público. Dicha evaluación exige analizar dos relaciones que se establecen en el ámbito de la violencia: la relación entre victimización y percepción de inseguridad; y la que se establece entre actitudes sociales y resolución pacífica de conflictos nacionales. Para ello, se analizaron las variables victimización, percepción de inseguridad, uso del espacio físico, actitudes hacia el sistema institucional político y social y hacia la resolución de conflictos nacionales, y las posibles relaciones entre ellas. Los datos para realizar el estudio se obtuvieron por medio de una encuesta que se llevó a cabo con 1 200 personas de 18 y 70 años de edad residentes en la ciudad de Santiago. Los resultados indican que Santiago es una ciudad de habitantes con temor y que el aumento de la percepción de inseguridad de sus habitantes contrasta con el hecho de que las tasas de victimización se hayan mantenido, más o menos, constantes en los años que precedieron a la encuesta. El temor se relaciona con el abandono del espacio público físico y sociopolítico, así como con el refugio en los espacios y la vida privados. La actitud de resolver los conflictos por medios no pacíficos es frecuente y se asocia en mayor medida con la inseguridad, la actitud negativa hacia la democracia y la falta de expectativas sobre el futuro del país. Los resultados de este estudio respaldan la idea de que para superar el temor la gente tiende a adaptarse a la realidad adoptando una postura conformista, homogeneizando las creencias y los comportamientos, y sobreestimando la fuerza como medio para resolver las diferencias.

  3. Interpretación de la prueba de tuberculina en niños y vacunados con BCG

    OpenAIRE

    Piñeiro Pérez, Roi

    2012-01-01

    Revisados 20 años de literatura médica, el debate sobre la conveniencia de la vacunación con Bacilo de Calmette-Guérin (BCG) continúa abierto. La OMS se muestra a favor de su utilización en países con endemia elevada de Tuberculosis (TB), pero no se ha esclarecido el beneficio ni las indicaciones de la inmunización en poblaciones con endemia intermedia o baja, y existen numerosos expertos que se muestran contrarios a su administración en cualquier caso. Existen muchas publicaciones sobre el ...

  4. Estudio de 100 casos de hemorragia uterina con legrado-biopsia

    Directory of Open Access Journals (Sweden)

    Germán Jordán

    1953-01-01

    Full Text Available El cáncer del cuerpo uterino se presenta con mayor frecuencia en la sexta década de la vida, y en relación con el cáncer del cuello uterino en una proporción de un caso por ocho, respectivamente. Su evolución y sintomatología, mucho más benignas y lentas que las del cáncer del cuello, hacen mas fácil su tratamiento y favorable su pronostico.

  5. pacientes con insuficiencia renal terminal

    Directory of Open Access Journals (Sweden)

    Karen Herrera Herrera

    2011-01-01

    Full Text Available La presente investigación fundamenta en la clínica psicoanalítica el estudio de dos casos de tres personas diagnosticadas con IRT que reciben tratamiento de hemodiálisis, en razón a que dadas las características y el aumento de los reportes que se presentan, ya esto se considera un problema de salud pública. El objetivo principal es describir las características dinámicas del proceso de duelo en pacientes con IRT en un centro de terapia renal de la ciudad de Cartagena. El procedimiento metodológico empleó un diseño de tipo cualitativo; la investigación se desarrolló con un diseño clínico mediante el estudio de casos, y fundamentada en la hermenéutica psicoanalítica. Todo esto respaldado en la historia clínica, la entrevista semiestructurada individual y familiar, los test proyectivos, test del dibujo de la figura humana Machover y TAT de Murray, para la debida integración de los análisis. Se concluye que predominan funciones fallidas de los progenitores y que son individuos provenientes de familias psicosomáticas, que utilizan la enfermedad para obtener un beneficio secundario.

  6. con bajo peso al nacer

    Directory of Open Access Journals (Sweden)

    Adriana Mora Antó

    2005-01-01

    Full Text Available Esta investigación dio cuenta de la relación entre el estilo de funcionamiento familiar, los patrones de crianza y las edades de desarrollo evolutivo en niños, nacidos con bajo peso. El estudio descriptivo correlacional se realizó con 41 niños y sus madres, aplicándose cuestionarios sobre funcionamiento familiar, prácticas de crianza y desarrollo infantil. Los resultados señalaron la existencia de un funcionamiento familiar caracterizado por una cohesión amalgamada y una adaptabilidad caótica, una disciplina complaciente, falta de control y de límites claros en la díada madre-hijo. Se trataba de familias monoparentales, donde la temprana edad de concepción, el madresolterismo y el apoyo de la familia extensa eran constantes. Las edades evolutivas registradas indicaron un desarrollo inferior a la edad cronológica, en la mayor parte de los casos; sin embargo, éstas tendieron a ser superiores al compararlas con la edades reales de los infantes. No se encontró una correlación estadísticamente significativa entre la edad de desarrollo y los diferentes factores del funcionamiento familiar para algunos de los rangos de edad considerados; sin embargo, no se lo descartó por completo, especialmente en lo referente al optimismo familiar

  7. Predictors of favorable soft tissue profile outcomes following Class II Twin-block treatment.

    Science.gov (United States)

    Kim, Ji-Eun; Mah, Su-Jung; Kim, Tae-Woo; Kim, Su-Jung; Park, Ki-Ho; Kang, Yoon-Goo

    2018-01-01

    The aim of this study was to determine cephalometric factors that help predict favorable soft-tissue profile outcomes following treatment with the Class II Twin-block appliance. Pre- and post-treatment lateral cephalograms of 45 patients treated with the Class II Twin-block appliance were retrospectively analyzed. Profile silhouettes were drawn from the cephalograms and evaluated by three orthodontists in order to determine the extent of improvement. Samples were divided into a favorable group (upper 30% of visual analogue scale [VAS] scores, n = 14) and an unfavorable group (lower 30% of VAS scores, n = 14). Skeletal and soft-tissue measurements were performed on the cephalograms and an intergroup comparison was conducted. An independent t -test revealed that the following pre-treatment values were lower in the favorable group compared to the unfavorable group: lower incisor to mandibular plane angle, lower incisor to pogonion distance, point A-nasion-point B angle, sella-nasion line (SN) to maxillary plane angle, SN to mandibular plane angle, gonial angle, and symphysis inclination. The favorable group had a larger incisor inclination to occlusal plane. Moreover, the favorable group showed larger post-treatment changes in gonial angle, B point projection, and pogonion projection than did the unfavorable group. Class II malocclusion patients with a low divergent skeletal pattern and reduced lower incisor protrusions are likely to show more improvement in soft-tissue profile outcomes following Class II Twin-block treatment.

  8. Validation of favor code linear elastic fracture solutions for finite-length flaw geometries

    International Nuclear Information System (INIS)

    Dickson, T.L.; Keeney, J.A.; Bryson, J.W.

    1995-01-01

    One of the current tasks within the US Nuclear Regulatory Commission (NRC)-funded Heavy Section Steel Technology Program (HSST) at Oak Ridge National Laboratory (ORNL) is the continuing development of the FAVOR (Fracture, analysis of Vessels: Oak Ridge) computer code. FAVOR performs structural integrity analyses of embrittled nuclear reactor pressure vessels (RPVs) with stainless steel cladding, to evaluate compliance with the applicable regulatory criteria. Since the initial release of FAVOR, the HSST program has continued to enhance the capabilities of the FAVOR code. ABAQUS, a nuclear quality assurance certified (NQA-1) general multidimensional finite element code with fracture mechanics capabilities, was used to generate a database of stress-intensity-factor influence coefficients (SIFICs) for a range of axially and circumferentially oriented semielliptical inner-surface flaw geometries applicable to RPVs with an internal radius (Ri) to wall thickness (w) ratio of 10. This database of SIRCs has been incorporated into a development version of FAVOR, providing it with the capability to perform deterministic and probabilistic fracture analyses of RPVs subjected to transients, such as pressurized thermal shock (PTS), for various flaw geometries. This paper discusses the SIFIC database, comparisons with other investigators, and some of the benchmark verification problem specifications and solutions

  9. Preliminary evaluation of the uranium favorability in the Kaiparowits Plateau Region, Garfield and Kane Counties, Utah

    International Nuclear Information System (INIS)

    Dubyk, W.S.; Young, P.

    1978-05-01

    The basal sandstone of the Chinle Formation (Upper Triassic) and the Salt Wash Member of the Morrison Formation (Upper Jurassic) in the Kaiparowits Plateau, southcentral Utah, were evaluated in terms of uranium potential. Both surface and subsurface data were utilized. Favorability of the basal Chinle sandstone was based on (1) presence of intermediate-size sandstone-filled channels cut into the Moenkopi; (2) presence of carbonaceous material; (3) an adequate source of uranium; and (4) gamma-ray anomalies from test-hole logs. Favorability of the Salt Wash Member of the Morrison Formation was based on (1) sandstone-mudstone ratios that approach equality, and (2) presence of thick sandstone lenses, carbonaceous material, and halos of light-tan to brown limonite staining. Although the basal Chinle sandstone and the Salt Wash Member of the Morrison contain sizable uranium deposits throughout much of the Colorado Plateau, both units lack characteristics that are favorable for significant uranium deposits in the Kaiparowits Plateau

  10. Uranium favorability of tertiary sedimentary rocks of the Pend Oreille River valley, Washington

    International Nuclear Information System (INIS)

    Marjaniemi, D.K.; Robins, J.W.

    1975-08-01

    Tertiary sedimentary rocks in the Pend Oreille River valley were investigated in a regional study to determine the favorability for potential uranium resources of northeastern Washington. This project involved measurement and sampling of surface sections, collection of samples from isolated outcrops, chemical and mineralogical analyses of samples, and examination of available water well logs. The Box Canyon Dam area north of Ione is judged to have very high favorability. Thick-bedded conglomerates interbedded with sandstones and silty sandstones compose the Tiger Formation in this area, and high radioactivity levels are found near the base of the formation. Uranophane is found along fracture surfaces or in veins. Carbonaceous material is present throughout the Tiger Formation in the area. Part of the broad Pend Oreille valley surrounding Cusick, Washington, is an area of high favorability. Potential host rocks in the Tiger Formation, consisting of arkosic sandstones interbedded with radioactive shales, probably extend throughout the subsurface part of this area. Carbonaceous material is present and some samples contain high concentrations of uranium. In addition, several other possible chemical indicators were found. The Tiger-Lost Creek area is rated as having medium favorability. The Tiger Formation contains very hard, poorly sorted granite conglomerate with some beds of arkosic sandstone and silty sandstone. The granite conglomerate was apparently derived from source rocks having relatively high uranium content. The lower part of the formation is more favorable than the upper part because of the presence of carbonaceous material, anomalously high concentrations of uranium, and other possible chemical indicators. The area west of Ione is judged to have low favorability, because of the very low permeability of the rocks and the very low uranium content

  11. Variables relacionadas con los factores protectores en estudiantes de una universidad pública colombiana, 2016

    OpenAIRE

    Jaramillo, C.P.; Vélez, C.; Hoyos, M.; Escobar, M.P.; Pico, M.E.

    2017-01-01

    Introducción: Los factores protectores se definen como aquellos que fomentan los comportamientos favorables y positivos y desestimulan e inhiben los comportamientos de riesgo, limitando los efectos de los riesgos a los cuales se exponen los individuos. El fomento de factores protectores facilita el desarrollo de comportamientos y hábitos saludables así como la prevención de factores de riesgo. Objetivo: Analizar las variables relacionadas con los factores protectores en estudiantes de una uni...

  12. Social-and-economic mechanism of formation of favorable investment attractiveness of the region

    Science.gov (United States)

    Tereshkina, Tatiana; Mottaeva, Angela; Andreeva, Larisa; Larinina, Tatyana

    2017-10-01

    The article is devoted to the matters of investment attractiveness of regions. The factors making the regional investments possible. The authors argue, that social-and-economic development of regions is connected with the formation of the financial mechanism, representing the set of forms and methods of the organization, planning and stimulation of financial-and-economic activity in the certain social-and-economic space. The proper mechanism of formation of favorable investment attractiveness are offered. Besides, the ways of elimination of limiting factors in formation of favorable investment attractiveness are offered.

  13. Conversando con...Momoyo Kaijima

    OpenAIRE

    Gómez Alonso, Carlos; Álvarez Isidro, Eva; Torres Barchino, Ana

    2017-01-01

    [ES] Momoyo Kaijima es profesora en la Facultad de Arte y Diseño de la Universidad de Tsukuba en la Prefectura de Ibaraki y profesora visitante en la ETH de Zürich, en Royal Academy of Fine Arts, en Rice School of Architecture y en Harvard GSD. A lo largo de los años, Atelier Bow Wow ha colaborado con Krešimir Rogina, arquitecto de Zagreb y socio de la firma internacional Penezic&Rogina, en la realización del Grožnjan International Summer School of Architecture, siendo Rogina el nexo indispen...

  14. Uranium favorability of the San Rafael Swell area, east-central Utah

    International Nuclear Information System (INIS)

    Mickle, D.G.; Jones, C.A.; Gallagher, G.L.; Young, P.; Dubyk, W.S.

    1977-10-01

    The San Rafael Swell project area in east-central Utah is approximately 3,000 sq mi and includes the San Rafael Swell anticline and the northern part of the Waterpocket Fold monocline at Capitol Reef. Rocks in the area are predominantly sedimentary rocks of Pennsylvanian through Cretaceous age. Important deposits of uranium in the project area are restricted to two formations, the Chinle (Triassic) and Morrison (Jurassic) Formations. A third formation, the White Rim Sandstone (Permian), was also studied because of reported exploration activity. The White Rim Sandstone is considered generally unfavorable on the basis of lithologic characteristics, distance from a possible source of uranium, lack of apparent mineralization, and the scarcity of anomalies on gamma-ray logs or in rock, water, and stream-sediment samples. The lower Chinle from the Moss Back Member down to the base of the formation is favorable because it is a known producer. New areas for exploration are all subsurface. Both Salt Wash and Brushy Basin Members of the Morrison Formation are favorable. The Salt Wash Member is favorable because it is a known producer. The Brushy Basin Member is favorable as a low-grade resource

  15. 41 CFR 101-39.404 - Claims in favor of the Government.

    Science.gov (United States)

    2010-07-01

    ... VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.4-Accidents and Claims § 101-39.404 Claims in favor of... Interagency Fleet Management System (IFMS) vehicle is at fault and that party can be reasonably identified... pertaining to the accident and its investigation to the servicing GSA IFMS fleet management center. The GSA...

  16. Challenging the Courtesy Bias Interpretation of Favorable Clients' Perceptions of Family Planning Delivery

    Science.gov (United States)

    Len, Federico R.; Lundgren, Rebecka; Huapaya, Ana; Sinai, Irit; Jennings, Victoria

    2007-01-01

    Favorable client perceptions of provider's interpersonal behavior in contraceptive delivery, documented in clinic exit questionnaires, appear to contradict results from qualitative evaluations and are attributed to clients' courtesy bias. In this study, trained simulated clients requested services from Ministry of Health providers in three…

  17. Favorable effects of skeletal muscle on bone are distinguished according to gender and skeletal sites

    Directory of Open Access Journals (Sweden)

    Kyoung Min Kim

    2017-03-01

    Conclusions: Higher RASM was significantly associated with lower risk for osteoporosis and the areas at the femur neck and total hip appeared to more likely be affected positively by muscle. Moreover, because males showed faster muscle loss with aging than females, the bones of males may be more prone to favorable effects of muscle.

  18. Does campaign finance imply political favors? The case of the 1998 Brazilian elections

    NARCIS (Netherlands)

    Feijen, E.

    2005-01-01

    This paper provides empirical evidence that campaign contributions are strongly associated with expectations of future firm-specific political favors. Using a novel dataset, we find that during the 1998 elections in Brazil higher campaign contributions to federal deputies were robustly associated

  19. Non-take-up of Tax-favored Savings Plans : Are Household Portfolios Optimal?

    NARCIS (Netherlands)

    Alessie, R.J.M.; Hochgürtel, S.; van Soest, A.H.O.

    2001-01-01

    Since the early nineties, the Dutch tax system allows for a tax-favored form of risk free savings through employer-sponsored savings plans (ESSPs).Under some conditions and up to a certain amount, the contributions to this plan are tax-deductible, and the returns as well as the withdrawals are

  20. High procedural fairness heightens the effect of outcome favorability on self-evaluations : An attributional analysis

    NARCIS (Netherlands)

    Brockner, J.; Heuer, L.; Magner, N.; Folger, R.; Umphress, E.; Bos, K. van den; Vermunt, Riël; Magner, M.; Siegel, P.

    2003-01-01

    Previous research has shown that outcome favorability and procedural fairness often interact to influence employees work attitudes and behaviors. Moreover, the form of the interaction effect depends upon the dependent variable. Relative to when procedural fairness is low, high procedural fairness:

  1. Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

    NARCIS (Netherlands)

    A.L. Walz (Amy L.); A.H.A.G. Ooms (Ariadne ); S. Gadd (Samantha); D.S. Gerhard (Daniela S.); M.A. Smith (Malcolm A.); J.M. GuidryAuvil (Jamie M.); D. Meerzaman (Daoud); Q.-R. Chen (Qing-Rong); C. Hsu (ChihHao); C. Yan (Chunhua); C. Nguyen (Cu); Y. Hu (Ying); R. Bowlby (Reanne); D. Brooks (Denise); Y. Ma (Yussanne); A.A. Mungall (Andrew J.); R.A. Moore (Richard A.); J. Schein (Jacqueline); M.A. Marra (Marco A.); V. Huff (Vicki); J.S. Dome (Jeffrey); Y.-Y. Chi (Yueh-Yun); C.G. Mullighan (Charles); J. Ma (Jing); D.A. Wheeler (David A.); O.A. Hampton (Oliver A.); N. Jafari (Nadereh); N. Ross (Nicole); J.M. Gastier-Foster (Julie); E.J. Perlman (Elizabeth J.)

    2015-01-01

    textabstractWe report the most common single-nucleotide substitution/deletion mutations in favorable histology Wilms tumors (FHWTs) to occur within SIX1/. 2 (7% of 534 tumors) and microRNA processing genes (miRNAPGs) DGCR8 and DROSHA (15% of 534 tumors). Comprehensive analysis of 77 FHWTs indicates

  2. Correlates of Perceived Favorability of Online Courses for Quantitative versus Qualitative Undergraduate Business Majors

    Science.gov (United States)

    Blau, Gary; Pred, Robert; Drennan, Rob B., Jr.; Kapanjie, Darin

    2016-01-01

    An online survey tested the association among background, technological, and course-related variables with perceived favorability of online courses for two independent samples of fall 2015 and spring 2016 business undergraduates taking at least one online or hybrid course. Results showed that perceived learning was a consistent positive correlate…

  3. 45 CFR 73.735-503 - Criminal provisions relating to gifts, entertainment, and favors.

    Science.gov (United States)

    2010-10-01

    ... insurance, profit-sharing, stock bonus or other employee welfare or benefit plan maintained by a former... 45 Public Welfare 1 2010-10-01 2010-10-01 false Criminal provisions relating to gifts, entertainment, and favors. 73.735-503 Section 73.735-503 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  4. Food irradiation - pros and cons

    International Nuclear Information System (INIS)

    1983-01-01

    The use of ionising radiation for food preservation is a much-disputed topic, both among experts and among consumers. Pros and cons of this issue were discussed in detail at the consumers' forum. Professor Dr. Johannes Friedrich Diehl, Director of the Institute for Biochemistry of the Food Research Centre, Karlsruhe, is a well-known supporter of the new method of food preservation; he sees advantages in the radiopreservation of food because, for example, losses due to inedibility are reduced, the danger of salmonellosis is decreased, just as the use of chemicals. He thinks this method to be without danger to health, shown by many years of experience. Opponents to food irradiation like Prof. Dr. Konrad Pfeilsticker, Professor for food science and food chemistry at the Bonn University deem the method to be unnecessary and raise the problem of qualitative changes caused in the food. In the course of the discussions, the pros and cons seemed to balance each other out. (orig./AJ) [de

  5. De paseo con los Bourbaki

    Directory of Open Access Journals (Sweden)

    Miquel Escudero

    2012-04-01

    Full Text Available Setenta y siete años después de la fundación del grupo Bourbaki, procedemos a una reflexión que puede ser útil para los estudiantes que acaso no sepan de su existencia, ni tan siquiera los de matemáticas. Sería interesante conocer que a este grupo se le debe el signo del vacío como conjunto. Con todo lo discutible que sea el método Bourbaki en su reinterpretación de la matemática, no cabe duda de su importante repercusión hasta el punto de que ha marcado una época. Hay un antes y un después tras su irrupción, ningún matemático de primera fila de la segunda mitad del siglo XX fue ajeno a su influjo, para encabezarlo o para reprobarlo. Comenzaron como una juvenil extravagancia, pero repleta de conocimientos y con decidida voluntad de aprehender el rigor de forma exhaustiva.

  6. Tratamiento del paciente con artrosis

    Directory of Open Access Journals (Sweden)

    Francisco Vargas Negrín

    2014-01-01

    Full Text Available El manejo terapéutico del paciente con artrosis tiene como objetivo disminuir la sintomatología dolorosa e inflamatoria, mejorar la capacidad funcional del paciente y la aplicación de intervenciones terapéuticas eficaces y lo más seguras posibles. Un enfoque centrado en el paciente implica su participación activa en el diseño del plan terapéutico y en la toma de decisiones informadas oportunas en todas las etapas de la enfermedad. La educación terapéutica, la actividad física y el ejercicio terapéutico junto con el control de peso, en caso de sobrepeso u obesidad, constituyen el núcleo central del tratamiento. Los autocuidados individuales y por los familiares son fundamentales en el control del día a día del paciente. El uso de terapias físicas, ayudas técnicas (bastón, etc. y de fármacos tipo analgésicos simples, opioides y antiinflamatorios tiene evidencias demostradas en el control del dolor, mejora la funcionalidad y la calidad de vida del paciente y una clara recomendación de uso en el tratamiento de la artrosis. La cirugía conservadora y la de reemplazo articular se indican en los casos en los que no se logran los objetivos terapéuticos en casos concretos.

  7. Associação do methimazole e do ondansetron à quimioterapia com cisplatina em cães submetidos a quatro diferentes protocolos de fluidoterapia Association of methimazole and ondansetron to cisplatin chemotherapy in dogs submitted to four different fluid therapy protocols

    Directory of Open Access Journals (Sweden)

    C.S.F. Repetti

    2007-06-01

    Full Text Available Utilizaram-se 12 cães, machos, distribuídos em quatro grupos (G experimentais, selecionados de acordo com o tempo de fluidoterapia com solução fisiológica 0,9%: G1 (sem fluidoterapia, G2 (uma hora de fluidoterapia antes da cisplatina, G3 (uma hora de fluidoterapia antes da cisplatina e uma hora após e G4 (duas horas de fluidoterapia antes da cisplatina e uma após. Todos os animais receberam a cisplatina (70mg/m², pela via intravenosa, sendo os ciclos de quimioterapia realizados em intervalos de três semanas, num total de três ciclos. O ondansetron (0,4mg/kg foi administrado pela via intravenosa, a cada oito horas, no dia da quimioterapia e, a seguir, a cada 12 horas, por dois dias. O methimazole (40mg/kg foi pela via oral, 30 minutos antes da cisplatina e quatro horas após. Avaliaram-se os parâmetros hematológicos, bioquímicos, urinários e dosagem de tiroxina e triiodotironina a cada sete dias até o término do experimento. Esse protocolo foi eficaz e seguro em cães que permaneceram sob fluidoterapia durante duas a três horas. Os animais que não receberam fluidoterapia e os que ficaram somente uma hora sob infusão intravenosa de solução fisiológica apresentaram alterações que resultaram em não-recomendação do protocolo.Twelve male dogs were divided in four experimental groups (G, which were selected according to the time of 0.9% saline fluid therapy: G1 (without saline therapy, G2 (an hour of saline therapy before receiving cisplatin, G3 (an hour of saline therapy before receiving cisplatin and one hour after and G4 (two hours of saline therapy before receiving cisplatin and one hour after. All the animals received 70mg/m² cisplatin, via intravenous, and the chemotherapy cycles were accomplished in intervals of three weeks, in a total of three cycles. Ondansetron (0.4mg/kg was administered via intravenous, every 8 hours, on the day of the chemotherapy and, from that, every 12 hours for two days. Methimazole (40mg

  8. Avaliação da qualidade de vida e toxicidades em pacientes com câncer colorretal tratados com quimioterapia adjuvante baseada em fluoropirimidinas Evaluation of the toxicity and quality of life in patients with colorectal cancer treated with chemotherapy

    Directory of Open Access Journals (Sweden)

    Vanessa Maria Nunes Roque

    2006-06-01

    Full Text Available RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, causadas pela própria doença e pelo tratamento, são motivo de muitos estudos. OBJETIVO: Avaliar nos doentes com câncer colorretal em tratamento quimioterápico, a toxicidade e possíveis alterações da qualidade de vida. MÉTODOS: Durante o período de março de 2001 a maio de 2003 no Ambulatório de Oncologia da Disciplina de Gastroenterologia Clínica da Universidade Federal de São Paulo, foram acompanhados 45 pacientes com câncer colorretal em tratamento quimioterápico adjuvante ou paliativo com 5-fluourouracil e ácido folínico durante seis ciclos. A toxicidade gastrointestinal e hematológica foi analisada utilizando-se as Recomendações para a Graduação da Toxicidade Aguda e Subaguda. Após o término de cada ciclo quimioterápico, os resultados foram anotados de acordo com os respectivos graus que variaram entre 0 e 4. A qualidade de vida foi pesquisada pelo questionário WHOQOL bref (World Health Organization Quality of Life que consta de 26 questões e é composto por 4 domínios: físico, psicológico, relações sociais e meio ambiente, no início, no 3° e no 6° ciclo de tratamento. RESULTADOS: Entre os 45 pacientes, 28 eram do sexo masculino, a média de idade foi de 58,4 anos (34 a 79 anos. Segundo a classificação da União Internacional Contra o Câncer, 34 (75,6% eram estádio II ou III e 11 estádio IV (24,4%. Quanto à localização, 64,4% eram de cólon. Em 57,7% a quimioterapia foi adjuvante e nos demais paliativa. As toxicidades mais comumente encontradas foram náuseas (42%, diarréia (38% e neutropenia (15,7%. Não houve diferença significante entre os graus de toxicidade nos diferentes ciclos, assim como entre os doentes em tratamento adjuvante ou paliativo. Quanto

  9. Fibrilación auricular en una paciente con megaorejuela auricular izquierda

    Directory of Open Access Journals (Sweden)

    Alejandro Villamil

    2007-01-01

    Full Text Available La FA constituye una de las arritmias sostenidas más frecuentes que motivan la consulta. El sustrato comprende diferentes mecanismos, entre los que se encuentra el agrandamiento auricular izquierdo. Presentamos el caso de una mujer de 33 años con antecedentes depalpitaciones, que ingresó en la guardia por FA de alta respuesta ventricular. En la radiografía de tórax se observó una deformación del borde izquierdo de la silueta cardíaca. Posteriormente,el ecocardiograma transesofágico y la resonancia magnética nuclear evidenciaron una megaorejuela aneurismática debida, probablemente, a un defecto pericárdico. La conducta fue anticoagulación oral y tratamiento con atenolol, con evolución favorable.

  10. Cons ICARUS, TIGER and Fascism

    Directory of Open Access Journals (Sweden)

    Janez Vrečko

    2010-12-01

    Full Text Available Like the scientists of their time, Russian artists in the 1920s considered gravity the central problem – a view which points to the close harmony between modern physics and the avant-garde. It was only with the constructivist movement that the Icarus revolution grasped the principles of the “mobile philosophy” (3.651 which was almost at the same time recognised by modern physics as well. The static view of the world became obsolete, space and time were no longer absolute values. It was necessary to transcend Euclidean geometry, shake off the political ʻshackles on one’s hands’ and surrender to Lisicki’s imaginary space, where “At 2000 metres in the air / there is no more perspective” (Integrals 276.  Kosovel’s Icarus project accorded with Tatlin’s, and both of them accorded with the quintessential aims of the constructivist movement. It is no accident that Kosovel wished to name one of his poetry collections The Dream of Icarus. Poems on the Icarus theme, such as “Cons Icarus”, “Evacuation of the Spirit”, “Eh, Hey”, “A Heart in Alcohol” etc. belong to the group of Kosovel’s conses which follow his “mobile philosophy” (3.650 and “letters growing into space” (Int. 282.  The question “Man, do you want up in the air?” (Int. 128 will remain a question until the moment when man is finally ready to transcend the existing boundary and dive “beyond”. Hence Kosovel’s clear-cut contrast between the “green windows of an illuminated / express on a viaduct”, which moves horizontally and is, like a water current, subject to the earth’s gravity, and “the spirit in space”, whose direction of motion is “the perpendicular of the spirit”, atectonicity. “The spirit burns in space”: fire is an element that knows vertical movement alone, the only one of the elements to outgrow and transcend the earth’s gravity, therefore it is associated with another mythological figure important for

  11. Adjunctive micronutrient supplementation for pulmonary tuberculosis Suplementación con micronutrientes como tratamiento adjunto para tuberculosis pulmonar

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    Rodrigo X Armijos

    2010-06-01

    tercer mes de la suplementación, la proporción de sujetos con BAAR negativo en el grupo de micronutrientes aumentó significativamente en relación con el grupo placebo (p= 0.03, que va asociado al previo (segundo mes incremento de los niveles de TNF-α, e IFN-γ y disminución de los niveles de IL-10. CONCLUSIONES: Suplementación con los micronutrientes aparentemente aceleran el efecto terapéutico de la quimioterapia. La negativización temprana del BAAR en esputo se asoció con la recuperación del estatus de zinc y la respuesta Thl. El efecto terapéutico de vitamina A es menos evidente.

  12. Qualidade de vida de pacientes com câncer de mama em terapia adjuvante Calidad de vida de pacientes con cáncer de mama en terapia adyuvante Quality of life of breast cancer patients in adjuvant therapy

    Directory of Open Access Journals (Sweden)

    Adriana Cristina Nicolussi

    2011-12-01

    Full Text Available O objetivo do estudo foi avaliar a Qualidade de Vida (QV, identificar os domínios afetados em pacientes com câncer de mama em terapia adjuvante e correlacioná-los com características sócio-demográficas, clínicas e terapêuticas. Estudo transversal, realizado com 35 pacientes entre agosto de 2007 e dezembro de 2008. Utilizou-se o instrumento Quality of Life Core-30-Questionnaire (QLQ-C30. A Qualidade de Vida geral foi considerada pouco satisfatória. Os domínios afetados foram: função emocional, insônia, dor e fadiga. Nas correlações, as pacientes acima de 60 anos apresentaram pior escore na função emocional, as submetidas à cirurgia referiram mais constipação, as que realizavam radioterapia obtiveram pior escore para QV geral e as que estavam em quimioterapia há mais de seis ciclos apresentaram a função emocional afetada e dispnéia. Concluiu-se que os tratamentos adjuvantes afetaram de algum modo as pacientes, causando déficit na função emocional e relataram mais sintomas, prejudicando assim sua QV.El objetivo fue evaluar la calidad de vida (CV, identificar los dominios afectados en pacientes con cáncer de mama en terapia adyuvante y correlacionarlos con las características socio-demográficas, clínicas y terapéuticas. Estudio transversal, con 35 pacientes, realizado entre agosto de 2007 y diciembre de 2008. Fue utilizado el instrumento Quality of Life Core-30-Questionnaire (QLQ-C30. La calidad de vida fue considerada poco satisfactoria. Los dominios más afectados fueron: función emocional, insomnio, dolor, fatiga. En las correlaciones, las pacientes con más de 60 años presentaron peores promedios en la función emocional, las pacientes que fueron sometidas a la cirugía refirieron más estreñimiento, las que recibían radioterapia presentaron peores promedios en CV general y las que habían recibido más de seis ciclos de quimioterapia presentaron la función emocional afectada y la disnea. Se concluyó que los

  13. Fare astronomia con piccoli telescopi

    CERN Document Server

    Gainer, Michael K

    2007-01-01

    Non sono necessariamente richiesti strumenti mastodontici per produrre risultati scientificamente validi nel campo dell’astronomia. Anche l’astrofilo dotato di un piccolo telescopio, con un diametro di soli 8-9 cm, può contribuire alla scienza del cielo realizzando utili osservazioni del Sole, della Luna, dei pianeti, delle comete, degli asteroidi, delle stelle doppie o variabili, delle nebulose e degli ammassi stellari. Il manuale di M.K. Gainer spiega quale sia la dotazione minima (un piccolo telescopio, un computer, una semplice fotocamera digitale), come utilizzarla, e quali siano le tecniche appropriate da adottare nelle osservazioni. Offre inoltre schemi per interpretare e ridurre i dati raccolti, nonché schede da compilare e da spedire ai centri di raccolta internazionali. Questo libro è il passaporto grazie al quale l’astrofilo può entrare a pieno titolo nel mondo affascinante della scienza astronomica.

  14. Most children with eosinophilic esophagitis have a favorable outcome as young adults.

    Science.gov (United States)

    Bohm, M; Jacobs, J W; Gupta, A; Gupta, S; Wo, J M

    2017-01-01

    The disease progression of eosinophilic esophagitis (EoE) from childhood into adulthood is unclear. To determine the clinical outcome of patients who were diagnosed with EoE as children, and who now are young adults. Children (adults (≥18 years old) were identified, and a structured telephone interview was conducted to obtain follow-up data on symptom prevalence (dysphagia to solids and liquids, nausea/vomiting, abdominal pain, and heartburn/regurgitation), food impaction, medication usage, health-care utilization, and resolution of atopy/food allergies. A favorable outcome was defined if EoE symptoms were resolved or improved by subjects' assessment. Unfavorable outcomes was defined as symptoms same or worse. Clinical variables that predicted a favorable outcome as an adult were examined. Mayo Dysphagia Scale (MDQ-30: scored 0-100) was administered to validate the outcome assessment. Mantel-Haenszel odds ratio and unpaired t-test were used. Fifty-eight subjects (64% male) who met study criteria were enrolled. Mean age at diagnosis was 12 years (range 4-17) and mean duration of follow-up was 8.3 years (2-16). As children, the most common presenting symptoms were abdominal pain (54%), dysphagia (33%), and vomiting (24%). As young adults, 47 subjects (81%) had a favorable outcome. Total MDQ-30 scores were 4.6 (0-30) and 14.1 (0-50) in subjects with favorable outcome and unfavorable outcome, respectively (P = 0.015). Two-thirds of subjects did not use steroids or proton pump inhibitors in the preceeding 12 months. Male children with EoE were four times more likely to have a favorable outcome as young adults compared with female children. Females were more likely to report nausea/vomiting as young adults (odds ratio 3.23, CI 0.97-10.60). Of all presenting symptoms in EoE children, dysphagia was the most likely to persist into adulthood (odds ratio 6.29, CI 1.85-21.38). Eighty one percent of EoE children had a favorable outcome as young adults. Most patients

  15. Capacidad comunitaria en beneficio de promover salud en la colectividad Community ability favoring health promotion in collectivity

    Directory of Open Access Journals (Sweden)

    Dulce V. Romeo Cepero

    2007-09-01

    Full Text Available En promoción de la salud, el empoderamiento es un proceso a través del cual la gente gana un mayor control sobre decisiones y acciones que afectan su salud. La educación en salud y la participación de la comunidad, son los caminos a la autorresponsabilidad, que deben encararse como un proceso largo y complejo. Con el deseo de indagar la competitividad de la comunidad del Consejo “Antonio Guiteras” en el municipio Habana del Este, en cuanto a su empoderamiento en beneficio de promover la salud de sus pobladores, y con el objetivo de evaluar la participación intersectorial en la gestión de salud, se realizó un estudio descriptivo en el que se encontró que se hace necesaria una práctica más consecuente de la “participación social y comunitaria” en la comunidad del Reparto para la solución de los problemas de salud, dependiendo de acciones intersectoriales, acciones comunitarias y prácticas individuales, así como también que dicha comunidad tiene una influencia limitada en las áreas de planificación y ejecución de los programas de salud. Se recomendó la necesidad de capacitar al personal de salud de la atención primaria y a los sectores y gobiernos con las herramientas técnicas, conceptuales y metodológicas necesarias para su papel de facilitador en la estrategia de salud que es la APS, así como impulsar la estrategia de Municipios por la Salud en el contexto local de la comunidad.In health promotion, strengthening is a process by which people achieves a greater control on decisions and actions affecting its health. Health education, and community involvement, are routes to self-responsibility, that be confronted like a long and complex process. To know community concerning in “Antonio Guiteras” Council in Habana del Este Municipality, as for its strengthening favoring the health promotion of its inhabitants, and to assess inter-sectorial involvement in health actions, a descriptive study was conducted in which it

  16. Factor estimulante de colonias de granulocitos en pacientes con cáncer Granulocyte-colony stimulating factor in patients with cancer

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    María Cristina Céspedes Quevedo

    2013-01-01

    Full Text Available Se efectuó un estudio descriptivo, longitudinal y prospectivo de 26 pacientes con cáncer en diferentes localizaciones asociado a leucopenia y neutropenia inducidas por citotóxicos, atendidos en el Servicio de Quimioterapia del Hospital Oncológico Docente "Conrado Benítez" de Santiago de Cuba, de mayo del 2011 a igual mes del 2012, con vistas a determinar el efecto del factor de colonias granulocítica recombinante Ior® LeukoCIM --producido por el Centro de Inmunología Molecular de Ciudad de La Habana-- en ellos mediante la realización de conteos globales de leucocitos y neutrófilos, antes y después de aplicar el tratamiento. En la serie predominaron el sexo femenino, el cáncer de mama y el estadio clínico II; también se obtuvo que 92,3 % de los pacientes respondieron satisfactoriamente a la terapia, el estadio clínico del cáncer no modificó el efecto mielodepresor de los citotóxicos ni el mieloestimulador de la hormona, y el cisplatino y la adriamicina se relacionaron con las neutropenias mayores y la falta de reacción al factor. Para finalizar, el Ior® LeukoCIM estimuló el sistema granulopoyético de la mayoría de los afectados.A descriptive, longitudinal and prospective study was conducted in 26 patients with cancer in different locations associated with leukopenia and neutropenia induced by cytotoxic drugs, treated at the Chemotherapy Department of "Conrado Benítez" Teaching Oncology Hospital of Santiago de Cuba, from May 2011 to the same month of 2012, with the purpose of determining the effect of the recombinant granulocyte-colony factor Ior® LeukoCIM --produced by the Center of Molecular Immunology in Havana city-- in them by means of global counts of leukocytes and neutrophils before and after applying the treatment. Female sex, breast cancer and clinical stage II prevailed in the series. It was also found that 92.3% of patients responded successfully to the therapy, the clinical stage of cancer did not modify the

  17. Tumor filodes de mama con metástasis en pulmón Phyllodes tumor of the breast with lung metastasis

    Directory of Open Access Journals (Sweden)

    Ernesto Arias Beatón

    2012-04-01

    Full Text Available Se describe el caso clínico de una paciente de 63 años de edad, quien ingresó en el Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba por presentar tos seca persistente, expectoración escasa (en ocasiones amarillenta, astenia y pérdida de peso. En el examen físico se palpó un tumor en la mama derecha, confirmado a través de ecografía y mamografía. Los resultados de la biopsia por aspiración con aguja fina fueron positivos de células neoplásicas, compatibles con carcinoma. La radiografía de tórax y la tomografía axial computarizada revelaron la presencia de imágenes metastásicas pulmonares, por lo cual se realizó la exéresis del tumor con un margen de seguridad de 2 cm. Mediante el estudio histopatológico se confirmó la existencia de un tumor filodes, de manera que fue preciso indicar 3 ciclos de quimioterapia (esquema CISCYVADACT, del que solo se cumplieron 2, pues la anciana evolucionó desfavorablemente y falleció 3 meses después.The case report of a 63-year-old patient is described, who was admitted to "Dr. Juan Bruno Zayas Alfonso" Teaching General Hospital of Santiago de Cuba due to persistent dry cough, little expectoration (sometimes yellowish, asthenia and loss of weight. On physical examination a tumor was palpated in the right breast, which was confirmed through sonography and mammogram. The results of the fine-needle biopsy were positive for neoplastic cells, consistent with carcinoma. Chest radiography and computerized axial tomography revealed the presence of lung metastatic images, reason why tumor excision with a safety margin of 2 cm was performed. The presence of phyllodes tumor was confirmed by means of the histopathologic study, so that it was necessary to indicate 3 cycles of chemotherapy (CISCYVADACT scheme, of which only two were administered as the old woman had an unfavorable course and she died 3 months later.

  18. European Organization for Research and Treatment of Cancer and Groupe d'Etude des Lymphomes de l'Adulte very favorable and favorable, lymphocyte-predominant Hodgkin disease.

    Science.gov (United States)

    Wilder, Richard B; Schlembach, Pamela J; Jones, Dan; Chronowski, Gregory M; Ha, Chul S; Younes, Anas; Hagemeister, Fredrick B; Barista, Ibrahim; Cabanillas, Fernando; Cox, James D

    2002-03-15

    Lymphocyte-predominant Hodgkin disease (LPHD) is rare and has a natural history different from that of classic Hodgkin disease. There is little information in the literature regarding the role of chemotherapy in patients with early-stage LPHD. The objective of this study was to examine recurrence free survival (RFS), overall survival (OS), and patterns of first recurrence in patients with LPHD who were treated with radiotherapy alone or with chemotherapy followed by radiotherapy. From 1963 to 1996, 48 consecutive patients ages 16-49 years (median, 28 years) with Ann Arbor Stage I (n = 30 patients) or Stage II (n = 18 patients), very favorable (VF; n = 5 patients) or favorable (F; n = 43 patients) LPHD, according to the European Organization for Research and Treatment of Cancer and Groupe d'Etude des Lymphomes de l'Adulte (EORTC-GELA) criteria, received radiotherapy alone (n = 37 patients) or received chemotherapy followed by radiotherapy (n = 11 patients). The percentages of patients with VF disease (11% vs. 9% in the radiotherapy group vs. the chemotherapy plus radiotherapy group, respectively) or F disease (89% vs. 91%, respectively) within the two treatment groups were similar (P = 1.00). A median of three cycles of chemotherapy with mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) or with mitoxantrone, vincristine, vinblastine, and prednisone (NOVP) was given initially to six patients and five patients, respectively. A median total radiotherapy dose of 40 grays (Gy) given in daily fractions of 2.0 Gy was delivered to both treatment groups. The median follow-up was 9.3 years, and 98% of patients were observed for > or = 3.0 years. RFS was similar for patients who were treated with radiotherapy alone and patients who were treated with chemotherapy followed by radiotherapy (10-year survival rates: 77% and 68%, respectively; P = 0.89). The OS rate also was similar for the two groups (10-year survival rates: 90% and 100%, respectively; P = 0

  19. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages

    Science.gov (United States)

    Cui, Yizhi; Zhou, Yanlong; Yin, Xingfeng; Guo, Jiahui; Zhang, Gong; Wang, Tong; He, Qing-Yu

    2016-01-01

    The exosome is a key initiator of pre-metastatic niche in numerous cancers, where macrophages serve as primary inducers of tumor microenvironment. However, the proteome that can be exosomally transported from cancer cells to macrophages has not been sufficiently characterized so far. Here, we used colorectal cancer (CRC) exosomes to educate tumor-favorable macrophages. With a SILAC-based mass spectrometry strategy, we successfully traced the proteome transported from CRC exosomes to macrophages. Such a proteome primarily focused on promoting cytoskeleton rearrangement, which was biologically validated with multiple cell lines. We reproduced the exosomal transportation of functional vimentin as a proof-of-concept example. In addition, we found that some CRC exosomes could be recognized by macrophages via Fc receptors. Therefore, we revealed the active and necessary role of exosomes secreted from CRC cells to transform cancer-favorable macrophages, with the cytoskeleton-centric proteins serving as the top functional unit. PMID:27602764

  20. Detecting Two-Spirit erotics: The fiction of Carole laFavor.

    Science.gov (United States)

    Tatonetti, Lisa

    2016-01-01

    This article examines the life and novels of Carole laFavor, arguing for her importance to and influence in Two-Spirit studies. Along with being a writer, laFavor was a powerful voice for social justice and Indigenous health sovereignty in Minnesota and the nation. Her two novels, Along the Journey River and Evil Dead Center, which both focus on Anishinaabe lesbian detective protagonist Renee LaRoche, are the first lesbian detective fiction published by a Native author. Renee's embrace of a specifically Two-Spirit erotics anchors her to family and brings her tribal community a powerful healing when she employs her skills to protect her people from instances of racism, abuse, and injustice. This article, then, reads these novels as the first of an emerging genre of texts that claim an overtly Two-Spirit erotic as well as vital precursors to the present embrace of sovereign erotics in Indigenous studies.

  1. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages.

    Science.gov (United States)

    Chen, Zhipeng; Yang, Lijuan; Cui, Yizhi; Zhou, Yanlong; Yin, Xingfeng; Guo, Jiahui; Zhang, Gong; Wang, Tong; He, Qing-Yu

    2016-10-11

    The exosome is a key initiator of pre-metastatic niche in numerous cancers, where macrophages serve as primary inducers of tumor microenvironment. However, the proteome that can be exosomally transported from cancer cells to macrophages has not been sufficiently characterized so far. Here, we used colorectal cancer (CRC) exosomes to educate tumor-favorable macrophages. With a SILAC-based mass spectrometry strategy, we successfully traced the proteome transported from CRC exosomes to macrophages. Such a proteome primarily focused on promoting cytoskeleton rearrangement, which was biologically validated with multiple cell lines. We reproduced the exosomal transportation of functional vimentin as a proof-of-concept example. In addition, we found that some CRC exosomes could be recognized by macrophages via Fc receptors. Therefore, we revealed the active and necessary role of exosomes secreted from CRC cells to transform cancer-favorable macrophages, with the cytoskeleton-centric proteins serving as the top functional unit.

  2. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism.

    Directory of Open Access Journals (Sweden)

    Stefan Pfattheicher

    Full Text Available The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk rated the profoundness of bullshit statements (using the BSR and provided favorability ratings of three Democratic (Hillary Clinton, Martin O'Malley, and Bernie Sanders and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump. Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O

  3. Lithofacies paleogeography and favorable gas exploration zones of Qixia and Maokou Fms in the Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Jingao Zhou

    2016-05-01

    Full Text Available In the Sichuan Basin, the Middle Permian marine carbonate rocks are important natural gas pay zones with immense exploration potential, but the facies belts and distribution situations of layered dolomite reservoirs are not clear, which hinders the progress in natural gas exploration. In view of the sedimentary background of the Sichuan Basin, field outcrop section, drilling data and seismic data were comprehensively analyzed with the favorable reservoir intervals in the framework of sequence stratigraphy as the key research units. Research results about its lithofacies paleogeography were obtained as follows. First, a gentle slope SW high and NE low was presented during the sedimentation of the Qixia Fm in the Middle Permian. In the Maokou Fm of the Middle Permian, however, a series of the N–W trending intra-platform rifts were developed in this setting, and eventually a paleogeographic pattern of NE-dipping alternative uplift and depression was evolved. Second, in the Qixia Fm, the transgressive tract was in an open platform environment and the highstand system tract evolved into a rimmed platform. And the platform margin beach in the area of Jiange–Ya'an is the favorable reservoir facies belt. And third, in the Maokou Fm, the transgressive tract was in the carbonate shelf environment and the highstand system tract evolved into a rimmed platform. And the platform margin reef flat in the area of Jiange–Ya'an and the syneclise margin beach in the area of Yanting–Guang'an are favorable reservoir facies belts. It is concluded that the two grain beach facies belts in the areas of Jiange–Ya'an and Yanting–Guang'an were the favorable zones for the large-scale development of Middle Permian layered dolomite reservoirs and they are the main target of subsequent natural gas exploration.

  4. Do professional norms in the banking industry favor risk-taking?

    OpenAIRE

    Cohn, Alain; Fehr, Ernst; Maréchal, Michel André

    2017-01-01

    In recent years, the banking industry has witnessed several cases of excessive risk-taking that frequently have been attributed to problematic professional norms. We conduct experiments with employees from several banks in which we manipulate the saliency of their professional identity and subsequently measure their risk aversion in a real stakes investment task. If bank employees are exposed to professional norms that favor risk-taking, they should become more willing to take risks when thei...

  5. Quantum-chemical studies on the favored and rare tautomers of neutral and redox adenine.

    Science.gov (United States)

    Raczyńska, Ewa D; Makowski, Mariusz; Zientara-Rytter, Katarzyna; Kolczyńska, Katarzyna; Stępniewski, Tomasz M; Hallmann, Małgorzata

    2013-02-21

    All possible twenty-three prototropic tautomers of neutral and redox adenine (nine amine and fourteen imine forms, including geometric isomerism of the exo ═NH group) were examined in vacuo {DFT(B3LYP)/6-311+G(d,p)}. The NH → NH conversions as well as those usually omitted, NH → CH and CH → CH, were considered. An interesting change of the tautomeric preference occurs when proceeding from neutral to reduced adenine. One-electron reduction favors the nonaromatic amine C8H-N10H tautomer. This tautomeric preference is similar to that (C2H) for reduced imidazole. Water molecules (PCM model) seem to not change this trend. They influence solely the relative energies. The DFT vertical detachment energy in the gas phase is positive for each tautomer, e.g., 0.03 eV for N9H-N10H and 1.84 eV for C8H-N10H. The DFT adiabatic electron affinity for the favored process, neutral N9H-N10H → reduced C8H-N10H (ground states), is equal to 0.18 eV at 0 K (ZPE included). One-electron oxidation does not change the tautomeric preference in the gas phase. The aromatic amine N9H-N10H tautomer is favored for the oxidized molecule similarly as for the neutral one. The DFT adiabatic ionization potential for the favored process, neutral N9H-N10H → oxidized N9H-N10H (ground states), is equal to 8.12 eV at 0 K (ZPE included). Water molecules (PCM model) seem to influence solely the composition of the tautomeric mixture and the relative energies. They change the energies of the oxidation and reduction processes by ca. 2 eV.

  6. Misperceiving Bullshit as Profound Is Associated with Favorable Views of Cruz, Rubio, Trump and Conservatism.

    Science.gov (United States)

    Pfattheicher, Stefan; Schindler, Simon

    2016-01-01

    The present research investigates the associations between holding favorable views of potential Democratic or Republican candidates for the US presidency 2016 and seeing profoundness in bullshit statements. In this contribution, bullshit is used as a technical term which is defined as communicative expression that lacks content, logic, or truth from the perspective of natural science. We used the Bullshit Receptivity scale (BSR) to measure seeing profoundness in bullshit statements. The BSR scale contains statements that have a correct syntactic structure and seem to be sound and meaningful on first reading but are actually vacuous. Participants (N = 196; obtained via Amazon Mechanical Turk) rated the profoundness of bullshit statements (using the BSR) and provided favorability ratings of three Democratic (Hillary Clinton, Martin O'Malley, and Bernie Sanders) and three Republican candidates for US president (Ted Cruz, Marco Rubio, and Donald Trump). Participants also completed a measure of political liberalism/conservatism. Results revealed that favorable views of all three Republican candidates were positively related to judging bullshit statements as profound. The smallest correlation was found for Donald Trump. Although we observe a positive association between bullshit and support for the three Democrat candidates, this relationship is both substantively small and statistically insignificant. The general measure of political liberalism/conservatism was also related to judging bullshit statements as profound in that individuals who were more politically conservative had a higher tendency to see profoundness in bullshit statements. Of note, these results were not due to a general tendency among conservatives to see profoundness in everything: Favorable views of Republican candidates and conservatism were not significantly related to profoundness ratings of mundane statements. In contrast, this was the case for Hillary Clinton and Martin O'Malley. Overall, small

  7. [Comparison of the quick Gram stain method to the B&M modified and favor methods].

    Science.gov (United States)

    Osawa, Kayo; Kataoka, Nobumasa; Maruo, Toshio

    2011-01-01

    The Gram stain is an established method for bacterial identification, but the time needed to carry out this stain is 2-3 min. We attempted to shorten this time and stained a total of 70 clinical specimens isolated from using the Bartholomew & Mittwer (B&M) modified or Favor methods with a 3 s duration for washing and staining steps. Results were plotted and analyzed using a Hue Saturation Intensity (HSI) model. The range based on a plot of the two methods with the HSI model was presented as a reference interval. Our results indicated that 100% (35/35) of strains were Gram positive and 97.1% (34/35) were Gram negative for the quick B&M modified method. In the quick Favor method, 80.0% (28/35) were Gram positive and 68.6% (24/35) of strains were Gram negative. We propose that the quick B&M modified method is equivalent to the standard Gram staining method and is superior to the quick Favor method.

  8. Comparison of job stress and obesity in nurses with favorable and unfavorable work schedules.

    Science.gov (United States)

    Han, Kihye; Trinkoff, Alison M; Storr, Carla L; Geiger-Brown, Jeanne; Johnson, Karen L; Park, Sungae

    2012-08-01

    To compare obesity-related factors between female nurses with favorable work schedules (WSs) and unfavorable WSs. In a cross-sectional study, 1724 female nurses were stratified by WS (favorable vs unfavorable). For each schedule type, the odds of obesity were related to health behaviors, home demands, and job stress using logistic regression models. Among nurses with unfavorable WSs, healthy behaviors (exercise, sleep) were inversely associated with obesity, whereas for those with favorable WSs, obese nurses reported significantly more unhealthy behaviors (smoking, alcohol use; odds ratio [OR], 1.19; 95% confidence interval [CI], 1.02-1.38), more physical lifting of children/dependents (OR, 1.43; 95% CI, 1.06-1.93), having more nurse input into their jobs (OR, 1.21; 95% CI, 1.02-1.44), yet less boss support at work (OR, 0.83; 95% CI, 0.68-0.99). Considering impacts of WSs on obesity and potential obesity-related health outcomes, healthful scheduling should be provided to nurses.

  9. The Study of Relationship Between Work Teams and Favoring Knowledge Management (Case: Bank Keshavarzi

    Directory of Open Access Journals (Sweden)

    Hamze Jamshidi Kohsari

    2011-03-01

    Full Text Available Knowledge management is a process that has been recently generated as an activity which isvery important in the dynamic environment, and in the competitive scene. We believe that KM is aprocess which its organizational knowledge is created from the individual knowledge of themembers of the organization. The relevant studies have indicated that organizing based on workteams could be considered a way to create the appropriate context for KM. However, thisorganizing based on work teams is not enough; it only has the necessary characteristics of the workteams that favor KM. Moreover, based on studies done, we distinguish which characteristics ofwork teams favor the KM process in its different phases (i.e. creation, transfer and integration. Inthis study, we conducted multiple regression and analysis of variance.Complementary skills (H2 and a climate of trust (H3 in work teams were more importantfactors that favor the management of organizational knowledge.This research is based on the Zarraga and Perez studies in 2006.

  10. Identificazione delle specie batteriche della placca subgengivale quale fattore di rischio per patologie parodontali in donne con variazioni ormonali fisiologiche e parafisiologiche

    OpenAIRE

    Privitera, Salvatore

    2014-01-01

    I principali obiettivi di questo studio sono stati quelli di valutare le implicazioni della menopausa sulla salute orale, nelle pazienti in trattamento con TOS (terapia ormonale sostitutiva) o meno, con particolare riferimento a modificazioni quali-quantitative dei principali batteri patogeni parodontali, che possono portare ad alterazioni dell equilibrio omeostatico del microbiota a favore di alcune specie più frequentemente coinvolte nell eziopatogenesi delle parodontopatie. A tal fine,...

  11. Depresion en pacientes con alteraciones del tiroides

    OpenAIRE

    Radanovic-Grguric´, Ljiljana; Filakovic´, Pavo; Barkic´, Jelena; Mandic´, Nikola; Karner, Ivan; Smoje, Juraj

    2003-01-01

    Nuestro estudio fue realizado en un grupo de 53 mujeres con disfunción tiroidea y 28 mujeres con depresión mayor. Empleamos la Escala de la Depresión de Hamilton, la Escala de Autoevaluación de la Depresión de Zung y la Escala sobre la Impresión Clínica Global. Los resultados del estudio demuestran que la mayoría de los pacientes con disfunción tiroidea se mostraron clínicamente significativos en cuanto al trastorno depresivo. Los episodios depresivos son más frecuentes en pacientes con hipot...

  12. Aprende Ajedrez con Rey - Parte 2

    OpenAIRE

    ESTÉVEZ MONTERO, RAÚL; Lloret Mauri, Jaime

    2016-01-01

    Es una pieza audiovisual creada con el objeto de atraer la atención de los niños de muy corta edad con el ajedrez y familiarizarlos con todas sus piezas y movimientos. Es una animación dirigida a un público infantil presentada por dibujos animados en 2D, en la que se ha intentado respetar en todo momento el argot de la comunidad ajedredística. En este video se presenta la segunda parte. Estévez Montero, R.; Lloret Mauri, J. (2016). Aprende Ajedrez con Rey - Parte 2. http://hdl.handle.net/1...

  13. Aprende Ajedrez con Rey - Parte 1

    OpenAIRE

    ESTÉVEZ MONTERO, RAÚL; Lloret Mauri, Jaime

    2016-01-01

    Es una pieza audiovisual creada con el objeto de atraer la atención de los niños de muy corta edad con el ajedrez y familiarizarlos con todas sus piezas y movimientos. Es una animación dirigida a un público infantil presentada por dibujos animados en 2D, en la que se ha intentado respetar en todo momento el argot de la comunidad ajedredística. En este video se presenta la primera parte. Estévez Montero, R.; Lloret Mauri, J. (2016). Aprende Ajedrez con Rey - Parte 1. http://hdl.handle.net/1...

  14. Global health actors no longer in favor of user fees: a documentary study.

    Science.gov (United States)

    Robert, Emilie; Ridde, Valéry

    2013-07-26

    Since the advent of health user fees in low- and middle-income countries in the 1980s, the discourse of global health actors (GHAs) has changed to the disadvantage of this type of healthcare financing mechanism. The aim of the study was to identify and analyze the stance of GHAs in the debate on user fees. We conducted documentary research using public documents published by and officially attributed to GHAs from 2005 to 2011. We categorized GHAs into four groups: intergovernmental organizations, international non-governmental organizations, government agencies, and working groups and networks. We then classified the GHAs according to their stance relative to the abolition of user fees, and conducted a thematic analysis of their discourse to understand the arguments used by each GHA to justify its stance. We identified 56 GHAs, for which we analyzed 140 documents. Among them, 55% were in favor of the abolition of user fees or in favor of free care at the point of delivery. None of the GHAs stated that they were in favor of user fees; however, 30% did not take a stand. Only the World Bank declares that it is both in favor of user fees and in favor of free care at point of service. GHAs generally circumscribe their stance to specific populations (pregnant women, children under 5 years, etc.) or to specific health services (primary, basic, essential). Three types of arguments are used by GHAs to justify their stance: economic, moral and ethical, and pragmatic. The principle of "user pays" seems to have fizzled. Production and dissemination of evidence, as well as certain advocacy networks, may have contributed to this change in discourse. However, GHAs should go a step further and translate their words into action, so that free healthcare at the point of delivery becomes a reality in low- and middle-income countries. They should provide technical and financial support to those countries that have chosen to implement user fee exemption policies, sometimes influenced

  15. Plantas cubanas con efecto antiinflamatorio

    Directory of Open Access Journals (Sweden)

    Ada Ivis Regalado Veloz

    Full Text Available La actividad antiinflamatoria suscita gran interés científico en el área farmacológica, debido a que muchas enfermedades en su evolución cursan por procesos inflamatorios (artritis reumatoide, ateroesclerosis, cáncer, diabetes, gota, asma, dermatitis, trastornos neurodegenerativos y diversas dolencias menores. Las enfermedades inflamatorias constituyen un problema de salud importante, debido a la falta de medicamentos eficaces y seguros para su uso por periodos prolongados. Hoy en día se trabaja en la búsqueda de alternativas de antiinflamatorios más seguros, en el que las plantas medicinales, una de las formas más antiguas de tratamiento, constituyen una elección a considerar. En este trabajo se realizó una revisión bibliográfica, sobre especies de plantas que crecen en Cuba que le reportan propiedades farmacológicas como antinflamatorios. En la revisión de la literatura se utilizó la base de datos Medline (vía PubMed, así como revistas nacionales desde el periodo de 2000 hasta el presente, con las palabras claves "inflamación" y "plantas cubanas antiinflamatorias" o "actividad antiinflamatoria" y "plantas medicinales".

  16. Hospitalidad, con y sin papeles

    Directory of Open Access Journals (Sweden)

    Ana Paula Penchaszadeh

    Full Text Available Resumen El objetivo de este artículo es vincular el trabajo sobre el archivo de Jacques Derrida con la experiencia de la hospitalidad. Se intentará mostrar que, por un lado, se trata siempre de los papeles, de la legitimidad que éstos otorgan o no tanto a nivel filosófico (deseo de poseer los papeles que autoricen tal o cual decisión interpretativa, como a nivel político ("tener papeles" como el principio básico de todo derecho a tener derechos, de todo derecho a la comunidad. Mas también, por otro lado, se intentará pensar aquello que arruina la idea misma de tener o no tener (papeles, la idea de propiedad, aquello que hace imposible fundar una decisión o identidad en última instancia y, por ende, una soberanía, una frontera. La hospitalidad, la llegada inminente del otro, representa un desafío político y ético para la filosofía: pues no se trata de un saber, sino de una experiencia transformando el sustrato del nos-otros, del ser común.

  17. Itinerari Musicali con la Wiild

    Directory of Open Access Journals (Sweden)

    Elisabetta Nanni

    2013-03-01

    Full Text Available La Wiild, acronimo di Wiimote Lavagna Digitale, è uno strumento didattico che utilizza il telecomando della Wii, il famoso gioco della Nintendo, insieme a un software libero, rendendolo così estremamente versatile. Non vincolato a software proprietario, il suo utilizzo è legato alla capacità dell’insegnante di ripartire dalla didattica, dalle risorse selezionate e dall’epistemologia di ogni singola disciplina, trovando così nel proprio contesto un ruolo per le tecnologie. Il contributo presenta ipotesi di lavoro per l’educazione musicale nella scuola secondaria di primo grado che si sviluppano sia attraverso lo studio del rapporto suono/segno con affinità pittoriche e successiva codificazione grafica, sia attraverso un’attività di laboratorio in cui co-costruire percorsi storico-musicali. La Wiild diventerà davvero utile ed efficace nel momento in cui, affiancando le risorse selezionate dal docente, verrà utilizzata senza essere notata, giocando un ruolo di strumento tecnologico «normale e trasparente».

  18. Bases tratadas con cemento, en California

    Directory of Open Access Journals (Sweden)

    Chinchilla, M.

    1962-05-01

    Full Text Available El uso de bases tratadas con cemento para autopistas se inició en el Estado de California en 1938, empleándose para carreteras con determinadas condiciones de tráfico. Inicialmente, se especificó el uso obligatorio de plantas mezcladoras para asegurar el debido control de las proporciones adecuadas.

  19. Some concepts of favorability for world-class-type uranium deposits in the northeastern United States

    Energy Technology Data Exchange (ETDEWEB)

    Adler, H.H.

    1981-03-01

    An account is given of concepts of favorability of geologic environments in the eastern United States for uranium deposits of several major types existing elsewhere in the world. The purpose is to convey some initial ideas about the interrelationships of the geology of the eastern United States and the geologic settings of certain of these world-class deposits. The study and report include consideration of uranium deposits other than those generally manifesting the geologic, geochemical and genetic characteristics associated with the conventional sandstone-type ores of the western United States.

  20. Some concepts of favorability for world-class-type uranium deposits in the northeastern United States

    International Nuclear Information System (INIS)

    Adler, H.H.

    1981-03-01

    An account is given of concepts of favorability of geologic environments in the eastern United States for uranium deposits of several major types existing elsewhere in the world. The purpose is to convey some initial ideas about the interrelationships of the geology of the eastern United States and the geologic settings of certain of these world-class deposits. The study and report include consideration of uranium deposits other than those generally manifesting the geologic, geochemical and genetic characteristics associated with the conventional sandstone-type ores of the western United States

  1. 2005 DAtF winter meeting - pleading in favor of a sensible energy mix

    International Nuclear Information System (INIS)

    2005-01-01

    The year's Winter Meeting of Deutsches Atomforum, which was held under the general heading of 'Pleading in Favor of a Sensible Energy Mix', dealt with the large variety of aspects and perspectives of this important key topic, also with respect to the sustainability factors, environment, economy, and social aspects. Twelve contributions, or statements, by representatives from politics, industry, society, and research covered different aspects of a 'sensible energy mix'. A round of politicians debated the subject controversially. The meeting, which was attended by more than 250 participants, thus opened 2005 with an interesting presentation of present and future topics of the power supply debate. (orig.)

  2. A case of invasive papillary breast carcinoma: Fierce façade with favorable prognosis

    Directory of Open Access Journals (Sweden)

    D Vani

    2015-01-01

    Full Text Available Invasive papillary carcinoma of the breast is a rare, distinct variant comprising approximately less than 1-2% of all newly diagnosed cases of breast carcinoma and is usually found in postmenopausal women with a more favorable prognosis. We report an unusual case in a 45-year-old perimenopausal female who came with a complaint of lump in right breast for duration of 1 year. A simple mastectomy was undertaken for histopathological study and immunohistochemistry (IHC which showed characteristic features of an invasive papillary breast carcinoma. We present this case in view of its rarity and to highlight this clinicopathological subtype for its good prognosis and to avoid overtreatment.

  3. Varieties of granitic uranium deposits and favorable exploration areas in the eastern United States

    International Nuclear Information System (INIS)

    Rogers, J.J.W.; Ragland, P.C.; Nishimori, R.K.; Greenberg, J.K.; Hauck, S.A.

    1978-01-01

    This paper is divided into three parts. First is an overview of the basic igneous processes that cause concentration of uranium and the types of rocks in which these deposits are most likely to occur. Second is a discussion of the source of uranium and the tectonic environments in which uranium-rich igneouos rocks are likely to form. Third is an application of these principles to the delineation of favorable belts for uranium exploration in crystalline rocks in the eastern United States. The paper is restricted to a discussion of those deposits in which high-uranium concentrations are caused by magmatic processes. 114 refs

  4. IMPACT OF ISLAMIC RELIGIOUS SYMBOL IN PRODUCING FAVORABLE ATTITUDE TOWARD ADVERTISEMENT

    Directory of Open Access Journals (Sweden)

    Abbas NASERI

    2012-06-01

    Full Text Available A review of the literature on religion and advertisement led to the identification of three lines of studies examining the influence of religion on advertising. These three lines of studies focused on attitude toward advertising of controversial products, presence of religious values in advertisements executions, and the consumers’ reactions to advertisement containing religious cues or symbols. The latter line has been followed modestly in Christian context but not in Islamic context of advertising. Hijab as a significant religious cue might peripherally generates a favorable attitude toward advertisement among Muslims. It is suggested that information processing theories like Elaboration Likelihood Model provides a pertinent theoretical framework to examine this effect empirically.

  5. Fuerza manual de adultos con discapacidad intelectual

    Directory of Open Access Journals (Sweden)

    Ruth Cabeza Ruiz

    2017-09-01

    Full Text Available Objetivo. Presentar una descripción de la fuerza de prensión manual de hombres y mujeres con discapacidad intelectual (DI y comparar los resultados con valores de referencia de otras personas con y sin discapacidad intelectual. Método. El presente trabajo es un estudio transversal observacional, financiado por la Fundación SAMU, en el que se evaluaron a 122 personas con DI (86 hombres y 36 mujeres durante el desarrollo de unas jornadas de carácter recreativo en las que participaron varias asociaciones de atención a este colectivo. La batería de test utilizada fue el Alpaha-Fit Test Battery for Adults. Resultados. Se presentan los resultados relacionados con las variables de fuerza del miembro superior (Hand Grip Strength por grupos de edad (20-24, 25- 29, 30-34, 35-39, 40-44, 45-49, 50-54, 55-59 años. Los datos muestran valores que oscilan desde los 31 kg en los hombres más jóvenes con DI hasta los 13.3 kg del grupo más maduro de mujeres. Estos hallazgos son similares a los valores de referencia de población con DI española. Sin embargo, son muy inferiores a los obtenidos por la población sin discapacidad de la misma edad. Conclusión. Los resultados evidencian el menor rendimiento de las personas con DI en pruebas de fuerza de prensión manual por lo que se hace evidente la necesidad de llevar a cabo programas de ejercicio físico o deporte con las personas con DI.

  6. Efectos favorables de la actividad física regular motivada en el trabajo sobre la tensión arterial y el perfil lipídico

    Directory of Open Access Journals (Sweden)

    Alfonso José Hernán

    2015-06-01

    Full Text Available Introducción: La inactividad física se ha incrementado de forma considerable en la sociedad actual pudiendo acarrear efectos perjudiciales para la salud. El ejercicio físico regular motivado en el trabajo podría ser una intervención de promoción de la salud y preventiva con beneficios a corto y largo plazo, por lo que es importante documentar sus efectos fisiológicos. Material y métodos: Estudio de corte transversal que representa la primera parte de un estudio prospectivo donde 121 trabajadores viales, de mantenimiento y de oficina (42 mujeres y 79 hombres recibieron un programa de motivación de actividad física. Se registró el grado de actividad física previa y actual. Se estudió el índice de masa corporal (IMC, la frecuencia cardíaca (FC, tensión arterial sistólica y diastólica (TAS, TAD, el pérfil lipídico, niveles de proteína C reactiva (PCR y hemoglobina glicosilada (HbA1c. La captación máxima de oxígeno fue cuantificada por medio de ergoespirometría. Análisis de regresión lineal fueron utilizados para estudiar asociaciones entre las variables de estudio con la respectiva inclusión de variables de confusión. Resultados: Las mujeres presentaron un pérfil lipídico más favorable y valores de IMC y tensión arterial menores en comparación con los hombres. La actividad física regular más de dos veces por semana estuvo asociada a niveles menores de colesterol total (p = 0,013 para 2-3 veces/semana; p = 0,025 para ≥4 vez / semana y lipoproteínas de baja densidad (LDL (p = 0,015 para 2-3 veces/emana; p = 0,022 para ≥4 veces / semana. Los valores de TAD eran más bajos en el grupo de los que reportó actividad física regular al menos cuatro veces por semana (p = 0,026. El efecto de la actividad física regular sobre la TAD fue más evidente en hombres que en mujeres (p = 0,01. Los niveles autoreportados de actividad física mostraron correlación con los niveles de captación máxima de oxígeno medidos

  7. La alimentación de la gestante adolescente: el cambio favorable Diet of the pregnant adolescent: the favorable change A alimentação da gestante adolescente: o câmbio favorável

    Directory of Open Access Journals (Sweden)

    BERNAL ROLDÁN MARÍA CARMEN

    2010-04-01

    Full Text Available El presente estudio de tipo cualitativo y etnográfico de pequeño alcance, tiene como objetivo describir el significado del cuidado de sí de un grupo de gestantes adolescentes y su hijo por nacer, con relación a la alimentación, a partir de sus prácticas, creencias y valores culturales, quienes asistieron a control prenatal a la Unidad de Atención Primaria (UPA de Candelaria la Nueva, Hospital Vista Hermosa, Ciudad Bolívar, Localidad 19 de Bogotá, en 2007. La información fue aportada por ocho adolescentes primigestantes de entre 17 y 19 años de edad, que estaban entre el cuarto y séptimo meses de gestación, sin patologías asociadas, que asistieron al primer control prenatal, seleccionadas intencionalmente y que estuvieron dispuestas a participar de la investigación (previo consentimiento informado. La recolección de datos se realizó a través de la entrevista etnográfica no estructurada; se obtuvo como resultado el significado del cuidado en las gestantes adolescentes y se aportaron tres grandes beneficios positivos del cuidado de la alimentación materna: cambio de hábito alimentario, alimentarse para proteger la salud del bebé y para que nazca sano, y alimentarse para proteger la salud de la madre adolescente. Dichos resultados, conjugados en el escenario cultural de las gestantes adolescentes, permiten explorar y conocer cómo se cuidan ellas a través de las prácticas soportadas en el saber como conocimiento y razón, y el uso como los artefactos que utiliza.The purpose of this limited scope, qualitative and ethnographic study is to describe the meaning of self-care for a group of pregnant adolescents and their unborn child, in relation to their diet, based on their practices, beliefs and cultural values, and who attended a prenatal checkup at the Primary Care Unit (UPA of Candelaria la Nueva, Vista Hermosa Hospital, Ciudad Bolívar, District number 19 de Bogotá, in 2007. The information contributed by eight first

  8. Experiencias de haber crecido con un padre/madre con trastorno mental severo (TMS)

    OpenAIRE

    Vivanco B, Gabriela; Grandón F, Pamela

    2016-01-01

    Introducción. La experiencia de vivir con personas que presentan un Trastorno Mental Severo (TMS) es difícil para las familias, en especial para los hijos quienes han sido poco estudiados. El objetivo de la investigación fue conocer cómo la experiencia de haber vivido con un padre o madre con un trastorno mental severo influyó en la infancia, adolescencia y adultez joven de sus hijos e hijas. Método. Se analizan las experiencias de convivencia con un padre/madre con TMS en 10 hijos (6 hombres...

  9. Resource allocation in offspring provisioning: An evaluation of the conditions favoring the evolution of matrotrophy

    Science.gov (United States)

    Trexler, Joel C.; DeAngelis, Donald L.

    2003-01-01

    We used analytic and simulation models to determine the ecological conditions favoring evolution of a matrotrophic fish from a lecithotrophic ancestor given a complex set of trade‐offs. Matrotrophy is the nourishment of viviparous embryos by resources provided between fertilization and parturition, while lecithotrophy describes embryo nourishment provided before fertilization. In fishes and reptiles, embryo nourishment encompasses a continuum from solely lecithotrophic to primarily matrotrophic. Matrotrophy has evolved independently from lecithotrophic ancestors many times in many groups. We assumed matrotrophy increased the number of offspring a viviparous female could gestate and evaluated conditions of food availability favoring lecithotrophy or matrotrophy. The matrotrophic strategy was superior when food resources exceeded demand during gestation but at a risk of overproduction and reproductive failure if food intake was limited. Matrotrophic females were leaner during gestation than lecithotrophic females, yielding shorter life spans. Our models suggest that matrotrophic embryo nourishment evolved in environments with high food availability, consistently exceeding energy requirements for maintaining relatively large broods. Embryo abortion with some resorption of invested energy is a necessary preadaptation to the evolution of matrotrophy. Future work should explore trade‐offs of age‐specific mortality and reproductive output for females maintaining different levels of fat storage during gestation.

  10. Role of Green Spaces in Favorable Microclimate Creating in Urban Environment (Exemplified by Italian Cities)

    Science.gov (United States)

    Finaeva, O.

    2017-11-01

    The article represents a brief analysis of factors that influence the development of an urban green space system: territorial and climatic conditions, cultural and historical background as well as the modern strategy of historic cities development. The introduction defines the concept of urban greening, green spaces and green space distribution. The environmental parameters influenced by green spaces are determined. By the example of Italian cities the principles of the urban greening system development are considered: the historical aspects of formation of the urban greening system in Italian cities are analyzed, the role of green spaces in the formation of the urban environment structure and the creation of a favorable microclimate is determined, and a set of measures aimed at its improvement is highlighted. The modern principles of urban greening systems development and their characteristic features are considered. Special attention is paid to the interrelation of architectural and green structures in the formation of a favorable microclimate and psychological comfort in the urban environment; various methods of greening are considered by the example of existing architectural complexes depending on the climate of the area and the landscape features. The examples for the choice of plants and the application of compositional techniques are given. The results represent the basic principles of developing an urban green spaces system. The conclusion summarizes the techniques aimed at the microclimate improvement in the urban environment.

  11. CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer

    Directory of Open Access Journals (Sweden)

    Marian S. Wettstein

    2015-01-01

    Full Text Available Aims. CD73 is a membrane associated 5′-ectonucleotidase that has been proposed as prognostic biomarker in various solid tumors. The aim of this study is to evaluate CD73 expression in a cohort of patients with primary bladder cancer in regard to its association with clinicopathological features and disease course. Methods. Tissue samples from 174 patients with a primary urothelial carcinoma were immunohistochemically assessed on a tissue microarray. Associations between CD73 expression and retrospectively obtained clinicopathological data were evaluated by contingency analysis. Survival analysis was performed to investigate the predictive value of CD73 within the subgroup of pTa and pT1 tumors in regard to progression-free survival (PFS. Results. High CD73 expression was found in 46 (26.4% patients and was significantly associated with lower stage, lower grade, less adjacent carcinoma in situ and with lower Ki-67 proliferation index. High CD73 immunoreactivity in the subgroup of pTa and pT1 tumors (n=158 was significantly associated with longer PFS (HR: 0.228; p=0.047 in univariable Cox regression analysis. Conclusion. High CD73 immunoreactivity was associated with favorable clinicopathological features. Furthermore, it predicts better outcome in the subgroup of pTa and pT1 tumors and may thus serve as additional tool for the selection of patients with favorable prognosis.

  12. Does Spontaneous Favorability to Power (vs. Universalism) Values Predict Spontaneous Prejudice and Discrimination?

    Science.gov (United States)

    Souchon, Nicolas; Maio, Gregory R; Hanel, Paul H P; Bardin, Brigitte

    2017-10-01

    We conducted five studies testing whether an implicit measure of favorability toward power over universalism values predicts spontaneous prejudice and discrimination. Studies 1 (N = 192) and 2 (N = 86) examined correlations between spontaneous favorability toward power (vs. universalism) values, achievement (vs. benevolence) values, and a spontaneous measure of prejudice toward ethnic minorities. Study 3 (N = 159) tested whether conditioning participants to associate power values with positive adjectives and universalism values with negative adjectives (or inversely) affects spontaneous prejudice. Study 4 (N = 95) tested whether decision bias toward female handball players could be predicted by spontaneous attitude toward power (vs. universalism) values. Study 5 (N = 123) examined correlations between spontaneous attitude toward power (vs. universalism) values, spontaneous importance toward power (vs. universalism) values, and spontaneous prejudice toward Black African people. Spontaneous positivity toward power (vs. universalism) values was associated with spontaneous negativity toward minorities and predicted gender bias in a decision task, whereas the explicit measures did not. These results indicate that the implicit assessment of evaluative responses attached to human values helps to model value-attitude-behavior relations. © 2016 The Authors. Journal of Personality Published by Wiley Periodicals, Inc.

  13. Favorable effect of moderate dose caffeine on the skeletal system in ovariectomized rats.

    Science.gov (United States)

    Folwarczna, Joanna; Pytlik, Maria; Zych, Maria; Cegieła, Urszula; Kaczmarczyk-Sedlak, Ilona; Nowińska, Barbara; Sliwiński, Leszek

    2013-10-01

    Caffeine, a methylxanthine present in coffee, has been postulated to be responsible for an increased risk of osteoporosis in coffee drinkers; however, the data are inconsistent. The aim of the present study was to investigate the effects of a moderate dose of caffeine on the skeletal system of rats with normal and decreased estrogen level (developing osteoporosis due to estrogen deficiency). The experiments were carried out on mature nonovariectomized and ovariectomized Wistar rats, divided into control rats and rats receiving caffeine once daily, 20 mg/kg p.o., for 4 wk. Serum bone turnover markers, bone mass, mass of bone mineral, calcium and phosphorus content, histomorphometric parameters, and bone mechanical properties were examined. Caffeine favorably affected the skeletal system of ovariectomized rats, slightly inhibiting the development of bone changes induced by estrogen deficiency (increasing bone mineralization, and improving the strength and structure of cancellous bone). Moreover, it favorably affected mechanical properties of compact bone. There were no significant effects of caffeine in rats with normal estrogen levels. In conclusion, results of the present study indicate that low-to-moderate caffeine intake may exert some beneficial effects on the skeletal system of mature organisms. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. [Who is against prevention? A map of policy actors favoring smoking in Spain].

    Science.gov (United States)

    Granero, Lluís; Villalbí, Joan Ramón; Gallego, Raquel

    2004-01-01

    For a comprehensive approach to policies on smoking, the map of actors related to tobacco and their political ties needs to be identified. The present article constitutes the first attempt at this task in Spain. Analysis of the press, industry publications, and interviews with key people. Active actors favoring smoking in Spain were identified and classified according to their characteristics, the sphere in which they act, and their preferred territorial arena. We identified tobacco companies (Altadis and Philip Morris dominate the market), tobacco trade organizations (tobacconists), front-line organizations created by the tobacco industry (The Smokers for Tolerance Club), organizations of tobacco growers, and processing companies. Distribution to retailers is dominated by Logista, owned by Altadis. Other sectors to take into account are vending companies and those manufacturing related products (cigarette paper, matches or lighters). The contacts of these actors with the public administration are reviewed, notable among which are the role of the Commissioner for the Tobacco Market, the Ministry of Agriculture, the Ministry of Finance and the Ministry of the Economy. Ties were also found with employers' organizations, some political parties, and unions, as well as with other sectors with social influence such as the media and advertising sectors. The map of actors favoring smoking in Spain is complex and goes beyond the confines of the tobacco industry. Understanding this web is crucial to promoting comprehensive prevention policies.

  15. Transcriptome changes favoring intramuscular fat deposition in the longissimus muscle following castration of bulls.

    Science.gov (United States)

    Jeong, J; Bong, J; Kim, G D; Joo, S T; Lee, H-J; Baik, M

    2013-10-01

    Castration increases intramuscular fat (IMF) deposition, improving beef quality in cattle. The present study was performed to determine the global transcriptome changes following castration of bulls and to identify genes associated with IMF deposition in the longissimus dorsi (LM) of Korean cattle. A customized bovine CombiMatrix oligonucleotide microarray was constructed, and transcriptome changes following castration were determined by microarray hybridization. Transcriptome comparison between bulls and steers indicated that 428 of 8,407 genes were differentially expressed in the LM by greater than two fold (P castration. Castration upregulated transcription of adipogenic perilipin 2 (PLIN2) and visfatin, lipogenic fatty acid synthase, fatty acid esterification 1-acylglycerol-3-phosphate O-acyltransferase 5, and many fatty acid oxidation-related genes. Many TCA cycle and OP genes were also transcriptionally upregulated. Correlation analysis indicated that the IMF content in the LM was highly correlated with mRNA levels of PLIN2 (r = 0.70, P castration shifts transcription of lipid metabolism genes, favoring IMF deposition by increasing adipogenesis, lipogenesis, and triglyceride synthesis. This study also indicated that castration increases transcription of genes involved in fatty acid oxidation and subsequent energy production (TCA and OP genes). Our microarray analysis provided novel information that castration alters the transcriptome associated with lipid/energy metabolism, favoring IMF deposition in the LM.

  16. FAVOR: A new fracture mechanics code for reactor pressure vessels subjected to pressurized thermal shock

    International Nuclear Information System (INIS)

    Dickson, T.L.

    1993-01-01

    This report discusses probabilistic fracture mechanics (PFM) analysis which is a major element of the comprehensive probabilistic methodology endorsed by the NRC for evaluation of the integrity of Pressurized Water Reactor (PWR) pressure vessels subjected to pressurized-thermal-shock (PTS) transients. It is anticipated that there will be an increasing need for an improved and validated PTS PFM code which is accepted by the NRC and utilities, as more plants approach the PTS screening criteria and are required to perform plant-specific analyses. The NRC funded Heavy Section Steel Technology (HSST) Program at Oak Ridge National Laboratories is currently developing the FAVOR (Fracture Analysis of Vessels: Oak Ridge) PTS PFM code, which is intended to meet this need. The FAVOR code incorporates the most important features of both OCA-P and VISA-II and contains some new capabilities such as PFM global modeling methodology, the capability to approximate the effects of thermal streaming on circumferential flaws located inside a plume region created by fluid and thermal stratification, a library of stress intensity factor influence coefficients, generated by the NQA-1 certified ABAQUS computer code, for an adequate range of two and three dimensional inside surface flaws, the flexibility to generate a variety of output reports, and user friendliness

  17. Evaluación económica de rituximab en combinación con fludarabina y ciclofosfamida en comparación con fludarabina y ciclofosfamida en el tratamiento de la leucemia linfática crónica Economic evaluation of rituximab added to fludarabine plus cyclophosphamide versus fludarabine plus cyclophosphamide for the treatment of chronic lymphocytic leukemia

    Directory of Open Access Journals (Sweden)

    Luis Felipe Casado

    2011-08-01

    Full Text Available Objetivos: Evaluar el coste-efectividad del esquema de rituximab, fludarabina y ciclofosfamida (R-FC en comparación con el de fludarabina y ciclofosfamida (FC en dos tipos de pacientes con leucemia linfática crónica (LLC: no tratados previamente o bien en recidiva/resistentes al tratamiento previo. Métodos: Dos modelos de Markov, utilizando los resultados publicados de superviviencia libre de progresión (SLP de pacientes con LLC tratados con R-FC o FC en primera o segunda línea, las tasas de progresión de la enfermedad y las tasas de mortalidad en España. A los estados de SLP y progresión se les asignaron utilidades obtenidas en un estudio sobre LLC. Los costes de los medicamentos y de los tratamientos de soporte, así como los años de vida ajustados por calidad (AVAC, se estimaron para un periodo de 10 años. Se efectuaron análisis de sensibilidad univariados y probabilísticos (Monte Carlo. Resultados: La adición de rituximab a la quimioterapia con FC aumentó los años de vida ganados (AVG y los AVAC tanto en primera como en segunda línea de tratamiento. La razón de coste-eficacia incremental fue de 20.703 € por AVG y de 19.343 € por AVAC con la primera línea de tratamiento, y de 23.183 € por AVG y 24.781 € por AVAC con la segunda línea de tratamiento. Conclusiones: En los pacientes con LLC no tratados previamente y en aquellos en recaída o resistentes al tratamiento previo, la adición de rituximab al esquema FC aumentó la esperanza de vida y los AVAC, y en ambos casos resultó ser un tratamiento coste-efectivo.Objectives: We evaluated the cost-effectiveness of rituximab added to the chemotherapy regimen of fludarabine plus cyclophosphamide (R-FC versus fludarabine plus cyclophosphamide (FC for the treatment of patients with previously untreated or relapsed/refractory chronic lymphocytic leukemia (CLL. Methods: Two Markov models were built, using published results on progression-free survival (PFS in patients

  18. 8 CFR 316.11 - Attachment to the Constitution; favorable disposition towards the good order and happiness.

    Science.gov (United States)

    2010-01-01

    ... disposition towards the good order and happiness. 316.11 Section 316.11 Aliens and Nationality DEPARTMENT OF... the Constitution; favorable disposition towards the good order and happiness. (a) General. An... favorably disposed toward the good order and happiness of the United States. Attachment implies a depth of...

  19. LA EDUCACION AMBIENTAL COMO ESPACIO FAVORABLE PARA EL DESARROLLO INTEGRAL (Pag: 146-152

    Directory of Open Access Journals (Sweden)

    María José Ortiz Torres

    2012-12-01

    Full Text Available El presente artículo desarrolla la relación intrínseca que involucra la educación ambiental con el desarrollo de la educación en el afecto en los jóvenes. A pesar de que el texto desarrolla este planteamiento a partir de una actividad de trabajo emocional en el grado octavo (801, jornada mañana, en el colegio Orlando Fals Borda, como práctica pedagógica, no resulta de interés describir la actividad sino las reflexiones que giran en torno al tema central. La relación entre educación ambiental y educación en el afecto posibilita entender las responsabilidades colectivas que permiten el desarrollo integral de un sujeto en un contexto dado. Este ensayo pretende abordar algunas de estas reflexiones alrededor de la formación de los sujetos con conciencia ambiental

  20. El maltrato en las personas con discapacidad

    OpenAIRE

    Revuelta, Lucerga

    2014-01-01

    El maltrato no solo se realiza por acción sino también por omisión, la indiferencia hacia la persona con discapacidad es una forma de maltrato muy frecuente. Por ejemplo, ignorar y desatender las necesidades de la persona con discapacidad o, al contrario, la sobreprotección son maneras de maltrato. Cuando a un niño con discapacidad el padre o cuidador le hace todo, el niño se siente agredido pues le están incapacitando más de lo que su enfermedad ya lo hace.

  1. Hiperalgesia asociada al tratamiento con opioides

    OpenAIRE

    A. Gil Martín; M. Moreno García; J. Sánchez-Rubio Ferrández; T. Molina García

    2014-01-01

    La hiperalgesia inducida por opioides es una reacción paradójica caracterizada por una percepción intensificada de dolor relacionada con el uso de estos medicamentos en ausencia de progresión de la enfermedad o de síndrome de retirada. A diferencia de los casos de tolerancia, definida como pérdida de potencia analgésica durante el uso prolongado de opioides, no se produce mejoría con el escalado de dosis. La hiperalgesia inducida por opioides se ha manifestado en pacientes con dosis de manten...

  2. Paciente con tumor de cuerpo carotideo

    Directory of Open Access Journals (Sweden)

    Mariuska Forteza Sáez

    Full Text Available Los tumores de cuerpo carotideo (paragangliomas son neoplasias altamente vascularizadas, muy poco frecuentes y generalmente benignas, originadas en los quimiorreceptores del cuerpo carotideo. Se presenta el caso de un paciente de 54 años, con aumento de volumen cervical derecho, asintomático, con estudio preoperatorio y angiografía realizados por tomografía axial computarizada, que resultan compatibles con tumor de cuerpo carotideo. Se realiza disección subadventicial, informando la biopsia paraganglioma. El tumor fue completamente resecado, sin evidencia de recurrencia y sin complicaciones.

  3. Some effects of favorable and adverse electric fields on pool boiling in dielectric fluids

    International Nuclear Information System (INIS)

    Masson, Viviana

    2001-01-01

    The effects of the application of an electric field on pool boiling in dielectric fluids were studied in this work.Two different geometries were used: one which is favorable to the bubble detachment (favorable electric field) and other which attract the bubbles toward the heater (adverse electric field).In the favorable electric field experiments, the void fraction and impact rate were calculated from the measured indicator function.Those parameters were obtained varying the probe-heater distance and the power to the heater.The results show a reduction of the void fraction with increasing applied voltage, probably caused by the combination of the dielectrophoretic force and a smaller bubble size due to the electric field application. Also, the impact rate decreases when a voltage is applied and the heat fluxes are close to the critical heat flux (CHF).On the other hand, the impact rate increases with voltage for moderate heat fluxes.Another interesting result is the approximately exponential decay of the void fraction and impact rate with the distance to the heater. Both the void fraction and the impact rate grow with heat flux if the heat fluxes are moderate, with or without applied voltage.For highest heat fluxes the void fraction still grows with heat flux if there are no applied electric fields while decreases with heat flux when there is an applied voltage. Similar behavior is observed in the impact rate.The boiling regimes was measured with adverse electric fields using two techniques.The heat transfer in the nucleate boiling regime was measured on an electrically powered heater.The results in these experiments show a reduction in the CHF of 10 % for saturation conditions and 10 kV of applied voltage, and a reduction of up to 40 % for 20 oC of liquid subcooling.The boiling curve corresponding to the transition and film boiling was performed with quenching experiments.An increase in the heat flux was achieved when an electric field was applied in spite of the

  4. Diagnóstico y seguimiento de pacientes con leucemia y transplantados de médula osea, mediante ditogenética molecular (FISH

    Directory of Open Access Journals (Sweden)

    Gonzálo Vásquez Palacio

    2006-04-01

    Full Text Available Tanto la citogenética convencional como la molecular en el estudio de los desórdenes hematológicos constituyen metodologías fundamentales para el diagnóstico y pronóstico de la enfermedad, así como para el seguimiento de la quimioterapia o transplantes de donantes de sexo diferente.

  5. Multivariate statistical analysis to investigate the subduction zone parameters favoring the occurrence of giant megathrust earthquakes

    Science.gov (United States)

    Brizzi, S.; Sandri, L.; Funiciello, F.; Corbi, F.; Piromallo, C.; Heuret, A.

    2018-03-01

    The observed maximum magnitude of subduction megathrust earthquakes is highly variable worldwide. One key question is which conditions, if any, favor the occurrence of giant earthquakes (Mw ≥ 8.5). Here we carry out a multivariate statistical study in order to investigate the factors affecting the maximum magnitude of subduction megathrust earthquakes. We find that the trench-parallel extent of subduction zones and the thickness of trench sediments provide the largest discriminating capability between subduction zones that have experienced giant earthquakes and those having significantly lower maximum magnitude. Monte Carlo simulations show that the observed spatial distribution of giant earthquakes cannot be explained by pure chance to a statistically significant level. We suggest that the combination of a long subduction zone with thick trench sediments likely promotes a great lateral rupture propagation, characteristic of almost all giant earthquakes.

  6. Teaching accreditation exams reveal grading biases favor women in male-dominated disciplines in France.

    Science.gov (United States)

    Breda, Thomas; Hillion, Mélina

    2016-07-29

    Discrimination against women is seen as one of the possible causes behind their underrepresentation in certain STEM (science, technology, engineering, and mathematics) subjects. We show that this is not the case for the competitive exams used to recruit almost all French secondary and postsecondary teachers and professors. Comparisons of oral non-gender-blind tests with written gender-blind tests for about 100,000 individuals observed in 11 different fields over the period 2006-2013 reveal a bias in favor of women that is strongly increasing with the extent of a field's male-domination. This bias turns from 3 to 5 percentile ranks for men in literature and foreign languages to about 10 percentile ranks for women in math, physics, or philosophy. These findings have implications for the debate over what interventions are appropriate to increase the representation of women in fields in which they are currently underrepresented. Copyright © 2016, American Association for the Advancement of Science.

  7. The experience of freedom in decisions - Questioning philosophical beliefs in favor of psychological determinants.

    Science.gov (United States)

    Lau, Stephan; Hiemisch, Anette; Baumeister, Roy F

    2015-05-01

    Six experiments tested two competing models of subjective freedom during decision-making. The process model is mainly based on philosophical conceptions of free will and assumes that features of the process of choosing affect subjective feelings of freedom. In contrast, the outcome model predicts that subjective freedom is due to positive outcomes that can be expected or are achieved by a decision. Results heavily favored the outcome model over the process model. For example, participants felt freer when choosing between two equally good than two equally bad options. Process features including number of options, complexity of decision, uncertainty, having the option to defer the decision, conflict among reasons, and investing high effort in choosing generally had no or even negative effects on subjective freedom. In contrast, participants reported high freedom with good outcomes and low freedom with bad outcomes, and ease of deciding increased subjective freedom, consistent with the outcome model. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Is there a Relationship between Patient Satisfaction and Favorable Surgical Outcomes?

    Science.gov (United States)

    Tevis, Sarah E.; Kennedy, Gregory D.; Kent, K. Craig

    2015-01-01

    Summary Satisfaction of patients with their health care is gaining importance as a measure of hospital quality due to public reporting of these values and an increasing connection between hospital reimbursement and scores on the current tool to measure satisfaction, the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. We found that high hospital and surgical volume and low rates of risk-adjusted mortality are associated with high patient satisfaction. However, other favorable patient outcomes are not consistently associated with positive satisfaction scores on HCAHPS. Contributors to patients' perceptions of their care are likely multifactorial and not related just to outcomes traditionally assessed by surgeons or hospitals. Moving in a direction of patient centered care, with a focus on increased understanding and involvement of patients in the care process, will likely strengthen the relationship between surgical outcomes and patient satisfaction. PMID:26299501

  9. Consistent Dalitz plot analysis of Cabibbo-favored D+ → K bar ππ+ decays

    Science.gov (United States)

    Niecknig, Franz; Kubis, Bastian

    2018-05-01

    We resume the study of the Cabibbo-favored charmed-meson decays D+ → K bar ππ+ in a dispersive framework that satisfies unitarity, analyticity, and crossing symmetry by construction. The formalism explicitly describes the strong final-state interactions between all three decay products and relies on pion-pion and pion-kaon phase shift input. For the first time, we show that the D+ →KSπ0π+ Dalitz plot obtained by the BESIII collaboration as well as the D+ →K-π+π+ Dalitz plot data by CLEO and FOCUS can be described consistently, exploiting the isospin relation between the two coupled decay channels that provides better constraints on the subtraction constants.

  10. Tunable Degradation Rate and Favorable Bioactivity of Porous Calcium Sulfate Scaffolds by Introducing Nano-Hydroxyapatite

    Directory of Open Access Journals (Sweden)

    Jianhua Zhou

    2016-12-01

    Full Text Available The bone scaffolds should possess suitable physicochemical properties and osteogenic activities. In this study, porous calcium sulfate (CaSO4 scaffolds were fabricated successfully via selected laser sintering (SLS. Nano-hydroxyapatite (nHAp, a bioactive material with a low degradation rate, was introduced into CaSO4 scaffolds to overcome the overquick absorption. The results demonstrated that nHAp could not only control the degradation rate of scaffolds by adjusting their content, but also improve the pH environment by alleviating the acidification progress during the degradation of CaSO4 scaffolds. Moreover, the improved scaffolds were covered completely with the apatite spherulites in simulated body fluid (SBF, showing their favorable bioactivity. In addition, the compression strength and fracture toughness were distinctly enhanced, which could be ascribed to large specific area of nHAp and the corresponding stress transfer.

  11. Selection of high risk groups among prognostically favorable patients with breast cancer.

    Science.gov (United States)

    Andersen, J A; Fischermann, K; Hou-Jensen, K; Henriksen, E; Andersen, K W; Johansen, H; Brincker, H; Mouridsen, H T; Castberg, T; Rossing, N; Rørth, M

    1981-01-01

    In a prospective, nationwide, decentralized breast cancer project conducted by The Danish Breast Cancer Cooperative Group (DBCG) the recurrence rate within the first year after surgery was analysed in relation to tumor anaplasia. One thousand forty-eight patients met the requirements of eligibility, i.e. tumor size less than or equal to 5 cm with negative axillary nodes, and no skin or deep invasion. The recurrence rates in tumors with anaplasia Grades I, II, and III were 4, 9, and 14%, respectively (p = 0.001). Therefore, it seems possible, prospectively, among otherwise prognostically favorable patients, to select a group with high risk of recurrence which might benefit from adjuvant systemic therapy. PMID:7247527

  12. Cosmology favoring extra radiation and sub-eV mass sterile neutrinos as an option.

    Science.gov (United States)

    Hamann, Jan; Hannestad, Steen; Raffelt, Georg G; Tamborra, Irene; Wong, Yvonne Y Y

    2010-10-29

    Precision cosmology and big-bang nucleosynthesis mildly favor extra radiation in the Universe beyond photons and ordinary neutrinos, lending support to the existence of low-mass sterile neutrinos. We use the WMAP 7-year data, small-scale cosmic microwave background observations from ACBAR, BICEP, and QuAD, the SDSS 7th data release, and measurement of the Hubble parameter from HST observations to derive credible regions for the assumed common mass scale m{s} and effective number N{s} of thermally excited sterile neutrino states. Our results are compatible with the existence of one or perhaps two sterile neutrinos, as suggested by LSND and MiniBooNE, if m{s} is in the sub-eV range.

  13. Evaluating Environmental Favorability for Tropical Cyclone Development with the Method of Point-Downscaling

    Directory of Open Access Journals (Sweden)

    David S Nolan

    2011-08-01

    Full Text Available A new method is presented to determine the favorability for tropical cyclone development of an atmospheric environment, as represented by a mean sounding of temperature, humidity, and wind as a function of height. A mesoscale model with nested, moving grids is used to simulate the evolution of a weak, precursor vortex in a large domain with doubly periodic boundary conditions. The equations of motion are modified to maintain arbitrary profiles of both zonal and meridional wind as a function of height, without the necessary large-scale temperature gradients that cannot be consistent with doubly periodic boundary conditions. Comparisons between simulations using the point-downscaling method and simulations using wind shear balanced by temperature gradients illustrate both the advantages and the limitations of the technique. Further examples of what can be learned with this method are presented using both idealized and observed soundings and wind profiles.

  14. Does the insurance effect of public and private transfers favor financial deepening? Evidence from rural Nicaragua

    Directory of Open Access Journals (Sweden)

    Emilio Hernandez

    2012-01-01

    Full Text Available The literature suggests CCTs and remittances may protect poor households from income risk. We present a theoretical framework that explores how this ‘insurance’ effect can change households’ decision to apply for a loan via changes in credit demand and supply. Empirical evidence from poor rural households in Nicaragua shows CCTs did not affect loan requests while remittances increased them. The risk protection provided by remittances seems stronger, relative to CCTs, such that improvements on borrowers’ expected marginal returns to a loan or on creditworthiness more than offset decreasing returns to additional income. This suggests those transfers that best protect households from income risk favor financial deepening in the context of segmented markets.

  15. Favorable Risk Selection in Medicare Advantage: Trends in Mortality and Plan Exits Among Nursing Home Beneficiaries

    Science.gov (United States)

    Goldberg, Elizabeth M.; Trivedi, Amal N.; Mor, Vincent; Jung, Hye-Young; Rahman, Momotazur

    2016-01-01

    The 2003 Medicare Modernization Act (MMA) increased payments to Medicare Advantage plans and instituted a new risk-adjustment payment model to reduce plans' incentives to enroll healthier Medicare beneficiaries and avoid those with higher costs. Whether the MMA reduced risk selection remains debatable. This study uses mortality differences, nursing home utilization, and switch rates to assess whether the MMA successfully decreased risk selection from 2000 to 2012. We found no decrease in the mortality difference or adjusted difference in nursing home use between plan beneficiaries pre- and post the MMA. Among beneficiaries with nursing home use, disenrollment from Medicare Advantage plans declined from 20% to 12%, but it remained 6 times higher than the switch rate from traditional Medicare to Medicare Advantage. These findings suggest that the MMA was not associated with reductions in favorable risk selection, as measured by mortality, nursing home use, and switch rates. PMID:27516452

  16. Prejudice, Social Dominance, and Similarity among People who Favor Integration of Minorities.

    Science.gov (United States)

    Martínez, Carmen; Saiz, José; Angosto, Josefa

    2016-04-12

    This study examines differences in prejudice, perceived similarity, and social dominance in members of the majority who favor integration as a means of minority acculturation. A total of 342 non-Gypsy Spanish participants filled out a questionnaire about their relationship to one of three outgroups: Maghrebians, Gypsies, and Latin Americans. Hierarchical cluster analysis showed that a three-cluster solution was most fitting for every outgroup. ANOVAs applied to the three clusters indicated significant differences in prejudice, perceived similarity, and social dominance. Referring to Gypsies the largest effect size was observed in manifest prejudice (η2 = .63), in Maghrebians, the largest effect size was observed in subtle prejudice (η2 =.77), while for Latin Americans, perceived similarity had the largest effect size η2 ( = .60). The results reveal a need to modify existing measures of integration; we recommend using questionnaires to measure behaviors that members of the majority would be willing to implement.

  17. Subcellular location of astrocytic calcium stores favors extrasynaptic neuron-astrocyte communication.

    Science.gov (United States)

    Patrushev, Ilya; Gavrilov, Nikolay; Turlapov, Vadim; Semyanov, Alexey

    2013-11-01

    Neuron-astrocyte interactions are important for brain computations and synaptic plasticity. Perisynaptic astrocytic processes (PAPs) contain a high density of transporters that are responsible for neurotransmitter clearance. Metabotropic glutamate receptors are thought to trigger Ca(2+) release from Ca(2+) stores in PAPs in response to synaptic activity. Our ultrastructural study revealed that PAPs are actually devoid of Ca(2+) stores and have a high surface-to-volume ratio favorable for uptake. Astrocytic processes containing Ca(2+) stores were located further away from the synapses and could therefore respond to changes in ambient glutamate. Thus, the anatomic data do not support communication involving Ca(2+) stores in tripartite synapses, but rather point to extrasynaptic communication. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Improved DNA electrophoresis in conditions favoring polyborates and lewis acid complexation.

    Directory of Open Access Journals (Sweden)

    Hari Singhal

    2010-06-01

    Full Text Available Spatial compression among the longer DNA fragments occurs during DNA electrophoresis in agarose and non-agarose gels when using certain ions in the conductive buffer, impairing the range of fragment sizes resolved well in a single gel. Substitutions using various polyhydroxyl anions supported the underlying phenomenon as the complexation of Lewis acids to DNA. We saw significant improvements using conditions (lithium borate 10 mM cations, pH 6.5 favoring the formation of borate polyanions and having lower conductance and Joule heating, delayed electrolyte exhaustion, faster electrophoretic run-speed, and sharper separation of DNA bands from 100 bp to 12 kb in a single run.

  19. Maternal Acceptance: Its Contribution to Children's Favorable Perceptions of Discipline and Moral Identity.

    Science.gov (United States)

    Patrick, Renee B; Gibbs, John C

    2016-01-01

    The authors examined the contribution of maternal acceptance or warmth to children's and adolescents' perceptions of discipline and formation of moral identity. The sample consisted of 93 male and female students from Grades 5, 8, and 10 and their mothers. Students completed measures pertaining to perceived maternal discipline practices and acceptance-rejection, as well as moral identity. A subsample of mothers reported on their accepting or rejecting actions toward their children. Children were more likely to feel accepted, if their mothers used inductive discipline (vs. power assertion and love withdrawal). Perceived acceptance was also related to more favorable discipline evaluations in certain respects. Specifically, inductive discipline recipients who felt accepted also evaluated induction as appropriate and responded to it with positive and guilt-related emotions. Power assertion was evaluated as appropriate among those children who did feel accepted. Finally, among inductive discipline recipients, those who felt accepted also reported higher moral identity.

  20. To favor survival under food shortage, the brain disables costly memory.

    Science.gov (United States)

    Plaçais, Pierre-Yves; Preat, Thomas

    2013-01-25

    The brain regulates energy homeostasis in the organism. Under resource shortage, the brain takes priority over peripheral organs for energy supply. But can the brain also down-regulate its own consumption to favor survival? We show that the brain of Drosophila specifically disables the costly formation of aversive long-term memory (LTM) upon starvation, a physiological state required for appetitive LTM formation. At the neural circuit level, the slow oscillations normally triggered in two pairs of dopaminergic neurons to enable aversive LTM formation were abolished in starved flies. Transient artificial activation of these neurons during training restored LTM formation in starved flies but at the price of a reduced survival. LTM formation is thus subject to adaptive plasticity that helps survival under food shortage.

  1. Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival.

    Science.gov (United States)

    Pai, Vaibhav P; Marshall, Aaron M; Hernandez, Laura L; Buckley, Arthur R; Horseman, Nelson D

    2009-01-01

    The breast microenvironment can either retard or accelerate the events associated with progression of latent cancers. However, the actions of local physiological mediators in the context of breast cancers are poorly understood. Serotonin (5-HT) is a critical local regulator of epithelial homeostasis in the breast and other organs. Herein, we report complex alterations in the intrinsic mammary gland serotonin system of human breast cancers. Serotonin biosynthetic capacity was analyzed in human breast tumor tissue microarrays using immunohistochemistry for tryptophan hydroxylase 1 (TPH1). Serotonin receptors (5-HT1-7) were analyzed in human breast tumors using the Oncomine database. Serotonin receptor expression, signal transduction, and 5-HT effects on breast cancer cell phenotype were compared in non-transformed and transformed human breast cells. In the context of the normal mammary gland, 5-HT acts as a physiological regulator of lactation and involution, in part by favoring growth arrest and cell death. This tightly regulated 5-HT system is subverted in multiple ways in human breast cancers. Specifically, TPH1 expression undergoes a non-linear change during progression, with increased expression during malignant progression. Correspondingly, the tightly regulated pattern of 5-HT receptors becomes dysregulated in human breast cancer cells, resulting in both ectopic expression of some isoforms and suppression of others. The receptor expression change is accompanied by altered downstream signaling of 5-HT receptors in human breast cancer cells, resulting in resistance to 5-HT-induced apoptosis, and stimulated proliferation. Our data constitutes the first report of direct involvement of 5-HT in human breast cancer. Increased 5-HT biosynthetic capacity accompanied by multiple changes in 5-HT receptor expression and signaling favor malignant progression of human breast cancer cells (for example, stimulated proliferation, inappropriate cell survival). This occurs

  2. Does community-based conservation shape favorable attitudes among locals? an empirical study from nepal.

    Science.gov (United States)

    Mehta, J N; Heinen, J T

    2001-08-01

    Like many developing countries, Nepal has adopted a community-based conservation (CBC) approach in recent years to manage its protected areas mainly in response to poor park-people relations. Among other things, under this approach the government has created new "people-oriented" conservation areas, formed and devolved legal authority to grassroots-level institutions to manage local resources, fostered infrastructure development, promoted tourism, and provided income-generating trainings to local people. Of interest to policy-makers and resource managers in Nepal and worldwide is whether this approach to conservation leads to improved attitudes on the part of local people. It is also important to know if personal costs and benefits associated with various intervention programs, and socioeconomic and demographic characteristics influence these attitudes. We explore these questions by looking at the experiences in Annapurna and Makalu-Barun Conservation Areas, Nepal, which have largely adopted a CBC approach in policy formulation, planning, and management. The research was conducted during 1996 and 1997; the data collection methods included random household questionnaire surveys, informal interviews, and review of official records and published literature. The results indicated that the majority of local people held favorable attitudes toward these conservation areas. Logistic regression results revealed that participation in training, benefit from tourism, wildlife depredation issue, ethnicity, gender, and education level were the significant predictors of local attitudes in one or the other conservation area. We conclude that the CBC approach has potential to shape favorable local attitudes and that these attitudes will be mediated by some personal attributes.

  3. On- and off-grid operation of hybrid renewable power plants: When are the economics favorable?

    Science.gov (United States)

    Petrakopoulou, F.; Santana, D.

    2016-12-01

    Hybrid renewable energy conversion systems offer a good alternative to conventional systems in locations where the extension of the electrical grid is difficult or not economical or where the cost of electricity is high. However, stand-alone operation implies net energy output restrictions (limited to exclusively serve the energy demand of a region), capacity oversizing and large storage facilities. In interconnected areas, on the other hand, the operational restrictions of the power stations change significantly and the efficiencies and costs of renewable technologies become more favorable. In this paper, the operation of three main renewable technologies (CSP, PV and wind) is studied assuming both hybrid and individual operation for both autonomous and inter-connected operation. The case study used is a Mediterranean island of ca. 3,000 inhabitants. Each system is optimized to fully cover the energy demand of the community. In addition, in the on-grid operation cases, it is required that the annual energy generated from the renewable sources is net positive (i.e., the island generates at least as much energy as it uses). It is found that when connected to the grid, hybridization of more than one technology is not required to satisfy the energy demand, as expected. Each of the renewable technologies investigated can satisfy the annual energy demand individually, without significant complications. In addition, the cost of electricity generated with the three studied technologies drops significantly for on-grid applications, when compared to off-grid operation. However, when compared to business-as-usual scenarios in both the on- and off-grid cases, both investigated hybrid and single-technology renewable scenarios are found to be economically viable. A sensitivity analysis reveals the limits of the acceptable costs that make the technologies favorable when compared to conventional alternatives.

  4. Prostate Cancer Diagnosed After Repeat Biopsies Have a Favorable Pathological Outcome but Similar Recurrence Rate

    Science.gov (United States)

    Lopez-Corona, Ernesto; Ohori, Makoto; Wheeler, Thomas M.; Reuter, Victor E.; Scardino, Peter T.; Kattan, Michael W.; Eastham, James A.

    2007-01-01

    Purpose We investigated whether repeat prostate biopsies are associated with more favorable prognoses, less extensive disease or higher rates of IC in patients who are ultimately diagnosed with prostate cancer and treated with RRP. Materials and Methods We examined standard clinical and pathological data on 1,357 patients treated with RRP from 1983 to 2001. In addition, we noted the rate of IC in a subgroup of 847 patients in whom tumor volume was measured. Results Cancer was found in 1,042 patients (77%) at the first biopsy, in 227 (17%) at the second biopsy, in 59 (4%) at the third biopsy and in 29 (2%) at the fourth or later biopsy. Patients with 2 or greater biopsies had a higher rate of clinical T1c stage cancer and larger prostates than patients with only 1 biopsy (each p <0.0001). After RRP patients with 1 biopsy had a lower rate of organ confined tumors (61% vs 75%, p <0.0001), and a higher rate of extracapsular extension, seminal vesicle invasion, lymph node metastases and Gleason sum 7 or greater than other patients. IC was found in 10% of patients with 1 biopsy and 18% of those with 2 or greater biopsies (p = 0.018). Despite these more favorable pathological outcomes there was no difference in biochemical recurrence rate. Conclusions Although we found that a greater number of biopsies was related to a better pathological outcome after RRP, the number of biopsies did not predict disease recurrence. The increasing number of biopsies currently being performed, especially in patients with larger prostates, likely results in higher rates of IC. PMID:16469581

  5. FAVOR: A new fracture mechanics code for reactor pressure vessels subjected to pressurized thermal shock

    International Nuclear Information System (INIS)

    Dickson, T.L.

    1993-01-01

    Probabilistic fracture mechanics (PFM) analysis is a major element of the comprehensive probabilistic methodology endorsed by the Nuclear Regulatory Commission (NRC) for evaluation of the integrity of pressurized water reactor pressure vessels subjected to pressurized-thermal-shock (PTS) transients. OCA-P and VISA-II are PTS PFM computer codes that are currently referenced in Regulatory Guide 1.154 as acceptable codes for performing plant-specific analyses. These codes perform PFM analyses to estimate the increase in vessel failure probability as the vessel accumulates radiation damage over the operating life of the vessel. Experience with the application of these codes in the last few years has provided insights into areas where they could be improved. As more plants approach the PTS screening criteria and are required to perform plant-specific analyses, there will be an increasing need for an improved and validated PTS PFM code that is accepted by the NRC and utilities. The NRC funded Heavy Section Steel Technology Program (HSST) at the Oak Ridge National Laboratory is currently developing the FAVOR (Fracture Analysis of Vessels: Oak Ridge) code, which is expected to meet this need. The FAVOR code incorporates the most important features of both OCA-P and VISA-II and contains some new capabilities such as (1) a PFM global modeling methodology; (2) the calculation of the axial stress component associated with coolant streaming beneath an inlet nozzle; (3) a library of stress intensity factor influence coefficients, generated by the NQA-1 certified ABAQUS computer code, for an appropriate range of two and three dimensional inner-surface flaws; (4) the flexibility to generate a variety of output reports; and (5) enhanced user friendliness

  6. Favorable effect of aerobic exercise on arterial pressure and aortic pulse wave velocity during stress testing.

    Science.gov (United States)

    Milatz, Florian; Ketelhut, Sascha; Ketelhut, Sascha; Ketelhut, Reinhard G

    2015-07-01

    Increased central pulse wave velocity is a major risk factor for cardiovascular disease. The favorable influence of exercise on arterial stiffness (AS) and blood pressure (BP) has been reported exclusively at rest. The present study investigated the influence of a single bout of acute cycling on AS and BP during recovery and, moreover, during cold pressor stress testing. 32 healthy men (33.7 ± 8 years, BMI 24 ± 2.5 kg/m²) performed a 60 minute endurance exercise on a bicycle ergometer (45 % VO2max). Before and after exercise aortic pulse wave velocity (aPWV) as well as central and peripheral BP were measured non-invasively at rest and at the end of a 2 minute cold pressor test (CPT). Even after 60 minutes of recovery aPWV (- 0.22 ± 0.3 m / sec) was significantly reduced (p Exercise decreased peripheral (- 8 ± 7 mmHg) and central (- 7 ± 8 mmHg) systolic BP as well as peripheral (- 3 ± 5 mmHg) and central (- 4 ± 7 mmHg) diastolic BP (p exercise, there was a significant reduction in aPWV (- 0.19 ± 0.3 m / sec), peripheral (- 6 ± 10 mmHg) and central (- 5 ± 8 mmHg) systolic BP as well as peripheral (- 3 ± 6 mmHg) and central (- 3 ± 6 mmHg) diastolic BP during CPT after exercise (p exercise leads not only to decreased BP but even more reduces aPWV as a measure of AS even after 60 minutes of recovery. In particular, the investigation provides evidence that acute moderate-intensity exercise has a favorable effect on BP and aPWV during stress testing.

  7. Association and Validation of Yield-Favored Alleles in Chinese Cultivars of Common Wheat (Triticumaestivum L..

    Directory of Open Access Journals (Sweden)

    Jie Guo

    Full Text Available Common wheat is one of the most important crops in China, which is the largest producer in the world. A set of 230 cultivars was used to identify yield-related loci by association mapping. This set was tested for seven yield-related traits, viz. plant height (PH, spike length (SL, spikelet number per spike (SNPS, kernel number per spike (KNPS, thousand-kernel weight (TKW, kernel weight per spike (KWPS, and sterile spikelet number (SSN per plant in four environments. A total of 106 simple sequence repeat (SSR markers distributed on all 21 chromosomes were used to screen the set. Twenty-one and 19 of them were associated with KNPS and TKW, respectively. Association mapping detected 73 significant associations across 50 SSRs, and the phenotypic variation explained (R2 by the associations ranged from 1.54 to 23.93%. The associated loci were distributed on all chromosomes except 4A, 7A, and 7D. Significant and potentially new alleles were present on 8 chromosomes, namely 1A, 1D, 2A, 2D, 3D, 4B, 5B, and 6B. Further analysis showed that genetic effects of associated loci were greatly influenced by association panels, and the R2 of crucial loci were lower in modern cultivars than in the mini core collection, probably caused by strong selection in wheat breeding. In order to confirm the results of association analysis, yield-related favorable alleles Xgwm135-1A138, Xgwm337-1D186, Xgwm102-2D144, and Xgwm132-6B128 were evaluated in a double haploid (DH population derived from Hanxuan10 xLumai14.These favorable alleles that were validated in various populations might be valuable in breeding for high-yield.

  8. Presa con revestimiento asfáltico

    Directory of Open Access Journals (Sweden)

    Proudfit, D. P.

    1960-07-01

    Full Text Available La presa denominada Montgomery se halla situada sobre el río South Platte River, a unos 8 km aguas arriba de la ciudad de Alma, del Estado de Colorado (EE. UU., y en la ladera oriental de la cordillera Continental Divide. El cuerpo o dique de esta presa está constituido por piedra, revestida con una capa de hormigón asfáltico en el paramento de contacto con el agua.

  9. Trastornos temporomandibulares en pacientes con maloclusiones

    Directory of Open Access Journals (Sweden)

    Luis Soto Cantero

    Full Text Available Introducción: existe una prevalencia de trastornos oclusales en gran medida relacionados con la presencia de disfunción temporomandibular. Objetivo: determinar el grado de disfunción temporomandibular según el Índice de Maglione en correspondencia con la prevalencia de maloclusiones en el área de salud del policlínico "Turcios Lima". Métodos: se realizó un estudio observacional descriptivo, de corte transversal, en la consulta de ortodoncia, de junio del 2008 a junio del 2009. De un universo constituido por los 280 pacientes que acudieron al servicio de ortodoncia en el período señalado con presencia de maloclusiones, se seleccionó una muestra de 84 pacientes por muestreo aleatorio simple, teniendo en cuenta los criterios de inclusión y exclusión realizados por criterios de expertos. Resultados: presentaban disfunción temporomandibular 74 pacientes y dentro de ellos 44 (52,4 % tenían disfunción grado II (Moderada. El 97 % de los pacientes con relación molar de clase II, presentaban disfunción temporomandibular. El 42,9 % de los pacientes con una maloclusión, presentaban disfunción grado I. El 60 % de los pacientes con dos maloclusiones presentaban disfunción grado II y el 66,7 % de los pacientes con tres maloclusiones, presentaban disfunción grado III. La mayor cantidad de pacientes tuvieron disfunción grado II (Moderada. Conclusiones: el mayor por ciento de los pacientes con disfunciones presentó una clase II molar y a medida que aumentó el número de maloclusiones aumentó también la severidad de la disfunción.

  10. Evidence favoring the involvement of CC chemokine receptor (CCR) 5 in T-lymphocyte accumulation in optic neuritis

    DEFF Research Database (Denmark)

    Sørensen, Torben Lykke; Ransohoff, R M; Jensen, J

    2003-01-01

    To define the relationships between levels of chemokine receptor (CCR)5+ T-cells in blood and cerebrospinal fluid (CSF) of optic neuritis (ON) and control patients (CON).......To define the relationships between levels of chemokine receptor (CCR)5+ T-cells in blood and cerebrospinal fluid (CSF) of optic neuritis (ON) and control patients (CON)....

  11. RadCon: A Radiological Consequences Model

    International Nuclear Information System (INIS)

    Crawford, J.; Domel, R.U.

    2000-05-01

    RadCon estimates the dose received by user selected groups in the population from an accidental release of radionuclides to the environment. The exposure pathways considered are external exposure from the cloud and ground and internal exposure from inhalation and ingestion of contaminated food. Atmospheric dispersion modelling is carried out externally to RadCon.Given a two dimensional time varying air and ground concentration of radioactive elements, RadCon allows the user to: view the air and ground concentration over the affected area, select optional parameters and calculate the dose to people,display the results to the user, and change the parameter values. RadCon offers two user interfaces: 1) the standard graphical user interface which is started using Java DoseApp at the command line, or by setting up a shortcut to this command (particularly when RadCon is installed on a PC) and 2) the text based interface used to generate information for the model inter-comparison exercise . This is initiated using Java BIOMASS at the command line, or an equivalent shortcut. The text based interface was developed for research purposes and is not generally available. Appendices A, B and C provide a summary of instructions on setting up RadCon. This will generally be carried out by the computer support personnel

  12. Adolescente femenino con granulomatosis de Wegener fulminante

    Directory of Open Access Journals (Sweden)

    S C Scheffler-Mendoza

    2017-01-01

    Full Text Available Adolescente femenino de 13 años de edad, originaria de Guerrero, grupo étnico mixteco, padres analfabetos y con poco entendimiento del español. Sin otros antecedentes de importancia para el padecimiento. Inició un mes previo con la aparición de una pápula hipercrómica en párpado superior derecho que en los 10 días previos al ingreso aumentó de volumen generando proptosis. Al interrogatorio se negó dolor, lagrimeo, fiebre, o pérdida de peso. Ingresó con fiebre (39.0°C, palidez generalizada, proptosis derecha con exposición de córnea y conjuntiva, eritema periorbitario, movimientos oculares y agudeza visual disminuidos (i.e. contaba dedos a 1 m, pupila con tendencia a midriasis, hiperreactividad a la luz, y fondo de ojo con papila hiperémica edematosa y tortuosidad peripapilar. El resto de exploración no mostró datos relevantes. Se hospitalizó para iniciar tratamiento antimicrobiano parenteral de amplio espectro (i.e. ceftriaxona y vancomicina y abordar proptosis unilateral.

  13. Campo magnético discontinuo en adultos con hipertensión arterial esencial

    OpenAIRE

    Enrique Arce Morera; Jorge Remis Sotelo; Jesús Hernández Méndez; Ismael Castañeda Rodríguez

    2003-01-01

    Se realizó un estudio piloto a 44 casos remitidos al Departamento de Fisioterapia de nuestro municipio con diagnóstico de hipertensión arterial esencial ligera y moderada, aplicándosele 15 sesiones de campo magnético discontinuo durante 15 min. Para buscar el grado de efectividad se utilizó el método estadístico de Mc Nemar, resultando muy significativa la reducción en los valores de la presión arterial, principalmente la máxima. Hubo un favorable efecto socioeconómico, pues se ahorró en el e...

  14. L’Albania apre agli accordi di collaborazione con i “nuovi culti”

    Directory of Open Access Journals (Sweden)

    Giovanni Cimbalo

    2011-10-01

    Full Text Available SOMMARIO: 1. Gli evangelici albanesi a favore della lingua, della cultura, dell’identità e dell’indipendenza - 2. La nuova Costituzione albanese e il ripristino della libertà religiosa - 3. Le trattative per la stipula dell’accordo di cooperazione - 4. I contenuti dell’accordo e i suoi effetti nel rapporto con la legislazione ordinaria a tutela della libertà religiosa - 5. La proiezione dell’efficacia degli accordi nell’area dell’Albania etnica – 6. Gli accordi di cooperazione: un modello esportabile?

  15. Favorable Attitudes Towards Serosorting are Associated With Overall Less Frequent Condom Use Among Young Black Men Having Sex Men

    Science.gov (United States)

    Crosby, Richard A.; Mena, Leandro; Geter, Angelica

    2018-01-01

    This study determined whether YBMSM endorsing serosorting are less likely to use condoms. A questionnaire assessed men’s attitudes towards serosorting with a three-item scale; various sexual risk behaviors were measured using a 90-day recall period. Favorable attitudes toward serosorting were associated with a greater likelihood of condomless sex as a top (P<.001) and as a bottom (P<.001), as well as a lower likelihood of using condoms with main partners (P=.003). Findings suggest that YBMSM having favorable attitudes toward serosorting may be more likely to report condomless sex than their counterparts without favorable attitudes. PMID:26433647

  16. RadConEd: A Graphical Data Editor for the Radiological Consequences Model, RadCon

    International Nuclear Information System (INIS)

    Crawford, J.; Domel, R.U.

    2000-05-01

    This document describes the application, RadConEd, which has been designed and implemented to enable users of the RadCon system to update these parameter files. The RadCon system is written in the Java programming language, and as such provides portability across computer platforms. The software described in this report was developed in line with the portability requirements of RadCon, thus providing a uniform user interface across computer platforms and bypassing the need of using system editors. In addition a number of data integrity measures were implemented

  17. Enfermedad coronaria en pacientes con psoriasis

    Directory of Open Access Journals (Sweden)

    Walter Masson

    2013-10-01

    Full Text Available Comunicaciones previas asociaron la psoriasis con la enfermedad coronaria. Desconocemos si en nuestro país o región existe dicha asociación. Se realizó un estudio transversal analizando los datos de la historia clínica electrónica de un sistema de salud de Buenos Aires. Analizamos todos los pacientes mayores de 18 años con diagnóstico de psoriasis entre el 1 de enero de 2003 y el 31 de julio de 2011 y los comparamos con un grupo control, en una relación 2:1, obtenido en forma aleatoria del mismo sistema de salud, apareados por edad y sexo. Determinamos la prevalencia de los factores de riesgo cardiovascular y de enfermedad coronaria. Analizamos la asociación entre la enfermedad coronaria y la psoriasis mediante análisis uni y multivariado. Se incluyeron 3 833 sujetos (1 286 pacientes con psoriasis y 2 547 controles. La prevalencia de hipertensión arterial (50% vs. 38%, p < 0.001, tabaquismo (25% vs. 17%, p < 0.001, diabetes (12% vs. 8%, p < 0.001 y enfermedad coronaria (4.98% vs. 3.06%, p = 0.003 fue mayor en los sujetos con psoriasis en comparación con el grupo control. Independientemente de la edad, la presencia de diabetes, hipertensión arterial o tabaquismo, hubo una asociación significativa entre la enfermedad coronaria y la psoriasis (OR 1.48, IC95% 1.04-2.11, p = 0.03. En conclusión, en esta población de Buenos Aires, los pacientes con psoriasis tuvieron una mayor prevalencia de diabetes, hipertensión arterial, tabaquismo y enfermedad coronaria. La asociación entre la psoriasis y la enfermedad coronaria fue independiente de los factores de riesgo explorados.

  18. Mincle Signaling Promotes Con-A Hepatitis

    Science.gov (United States)

    Greco, Stephanie H.; Torres-Hernandez, Alejandro; Kalabin, Aleksandr; Whiteman, Clint; Rokosh, Rae; Ravirala, Sushma; Ochi, Atsuo; Gutierrez, Johana; Salyana, Muhammad Atif; Mani, Vishnu R.; Nagaraj, Savitha V.; Deutsch, Michael; Seifert, Lena; Daley, Donnele; Barilla, Rocky; Hundeyin, Mautin; Nikifrov, Yuriy; Tejada, Karla; Gelb, Bruce E.; Katz, Steven C.; Miller, George

    2016-01-01

    Concanavalin-A (Con-A) hepatitis is regarded as a T cell-mediated model of acute liver injury. Mincle is a C-type lectin receptor (CLR) that is critical in the immune response to mycobacteria and fungi, but does not have a well-defined role in pre-clinical models of non-pathogen mediated inflammation. Since Mincle can ligate the cell death ligand SAP130, we postulated that Mincle signaling drives intrahepatic inflammation and liver injury in Con-A hepatitis. Acute liver injury was assessed in the murine Con-A hepatitis model using C57BL/6, Mincle−/−, and Dectin-1−/− mice. The role of C/EBPβ and HIF-1α signaling was assessed using selective inhibitors. We found that Mincle was highly expressed in hepatic innate inflammatory cells and endothelial cells in both mice and humans. Furthermore, sterile Mincle ligands and Mincle signaling intermediates were increased in the murine liver in Con-A hepatitis. Most significantly, Mincle deletion or blockade protected against Con-A hepatitis whereas Mincle ligation exacerbated disease. Bone marrow chimeric and adoptive transfer experiments suggested that Mincle signaling in infiltrating myeloid cells dictates disease phenotype. Conversely, signaling via other CLRs did not alter disease course. Mechanistically, we found that Mincle blockade decreased the NF-κβ related signaling intermediates, C/EBPβ and HIF-1α, both of which are necessary in macrophage-mediated inflammatory responses. Accordingly, Mincle deletion lowered production of nitrites in Con-A hepatitis and inhibition of both C/EBPβ and HIF1-α reduced the severity of liver disease. Our work implicates a novel innate immune driver of Con-A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation. PMID:27559045

  19. Mincle Signaling Promotes Con A Hepatitis.

    Science.gov (United States)

    Greco, Stephanie H; Torres-Hernandez, Alejandro; Kalabin, Aleksandr; Whiteman, Clint; Rokosh, Rae; Ravirala, Sushma; Ochi, Atsuo; Gutierrez, Johana; Salyana, Muhammad Atif; Mani, Vishnu R; Nagaraj, Savitha V; Deutsch, Michael; Seifert, Lena; Daley, Donnele; Barilla, Rocky; Hundeyin, Mautin; Nikifrov, Yuriy; Tejada, Karla; Gelb, Bruce E; Katz, Steven C; Miller, George

    2016-10-01

    Con A hepatitis is regarded as a T cell-mediated model of acute liver injury. Mincle is a C-type lectin receptor that is critical in the immune response to mycobacteria and fungi but does not have a well-defined role in preclinical models of non-pathogen-mediated inflammation. Because Mincle can ligate the cell death ligand SAP130, we postulated that Mincle signaling drives intrahepatic inflammation and liver injury in Con A hepatitis. Acute liver injury was assessed in the murine Con A hepatitis model using C57BL/6, Mincle(-/-), and Dectin-1(-/-) mice. The role of C/EBPβ and hypoxia-inducible factor-1α (HIF-1α) signaling was assessed using selective inhibitors. We found that Mincle was highly expressed in hepatic innate inflammatory cells and endothelial cells in both mice and humans. Furthermore, sterile Mincle ligands and Mincle signaling intermediates were increased in the murine liver in Con A hepatitis. Most significantly, Mincle deletion or blockade protected against Con A hepatitis, whereas Mincle ligation exacerbated disease. Bone marrow chimeric and adoptive transfer experiments suggested that Mincle signaling in infiltrating myeloid cells dictates disease phenotype. Conversely, signaling via other C-type lectin receptors did not alter disease course. Mechanistically, we found that Mincle blockade decreased the NF-κβ-related signaling intermediates C/EBPβ and HIF-1α, both of which are necessary in macrophage-mediated inflammatory responses. Accordingly, Mincle deletion lowered production of nitrites in Con A hepatitis and inhibition of both C/EBPβ and HIF-1α reduced the severity of liver disease. Our work implicates a novel innate immune driver of Con A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation. Copyright © 2016 by The American Association of Immunologists, Inc.

  20. Favorable prognostic value of SOCS2 and IGF-I in breast cancer

    International Nuclear Information System (INIS)

    Haffner, Michael C; Petridou, Barbara; Peyrat, Jean Phillipe; Révillion, Françoise; Müller-Holzner, Elisabeth; Daxenbichler, Günter; Marth, Christian; Doppler, Wolfgang

    2007-01-01

    Suppressor of cytokine signaling (SOCS) proteins comprise a protein family, which has initially been described as STAT induced inhibitors of the Jak/Stat pathway. Recent in vivo and in vitro studies suggest that SOCS proteins are also implicated in cancer. The STAT5 induced IGF-I acts as an endocrine and para/autocrine growth and differentiation factor in mammary gland development. Whereas high levels of circulating IGF-I have been associated with increased cancer risk, the role of autocrine acting IGF-I is less clear. The present study is aimed to elucidate the clinicopathological features associated with SOCS1, SOCS2, SOCS3, CIS and IGF-I expression in breast cancer. We determined the mRNA expression levels of SOCS1, SOCS2, SOCS3, CIS and IGF-I in 89 primary breast cancers by reverse transcriptase PCR. SOCS2 protein expression was further evaluated by immuno-blot and immunohistochemistry. SOCS2 expression inversely correlated with histopathological grade and ER positive tumors exhibited higher SOCS2 levels. Patients with high SOCS2 expression lived significantly longer (108.7 vs. 77.7 months; P = 0.015) and high SOCS2 expression proved to be an independent predictor for good prognosis (HR = 0.45, 95% CI 0.23 – 0.91, P = 0.026). In analogy to SOCS2, high IGF-I expression was an independent predictor for good prognosis in the entire patient cohort. In the subgroup of patients with lymph-node negative disease, high IGF-I was a strong predictor for favorable outcome in terms of overall survival and relapse free survival (HR = 0.075, 95% CI 0.014 – 0.388, P = 0.002). This is the first report on the favorable prognostic value of high SOCS2 expression in primary mammary carcinomas. Furthermore a strong association of high IGF-I expression levels with good prognosis was observed especially in lymph-node negative patients. Our results suggest that high expression of the STAT5 target genes SOCS2 and IGF-I is a feature of differentiated and less malignant tumors

  1. Favorable prognostic value of SOCS2 and IGF-I in breast cancer

    Directory of Open Access Journals (Sweden)

    Daxenbichler Günter

    2007-07-01

    Full Text Available Abstract Background Suppressor of cytokine signaling (SOCS proteins comprise a protein family, which has initially been described as STAT induced inhibitors of the Jak/Stat pathway. Recent in vivo and in vitro studies suggest that SOCS proteins are also implicated in cancer. The STAT5 induced IGF-I acts as an endocrine and para/autocrine growth and differentiation factor in mammary gland development. Whereas high levels of circulating IGF-I have been associated with increased cancer risk, the role of autocrine acting IGF-I is less clear. The present study is aimed to elucidate the clinicopathological features associated with SOCS1, SOCS2, SOCS3, CIS and IGF-I expression in breast cancer. Methods We determined the mRNA expression levels of SOCS1, SOCS2, SOCS3, CIS and IGF-I in 89 primary breast cancers by reverse transcriptase PCR. SOCS2 protein expression was further evaluated by immuno-blot and immunohistochemistry. Results SOCS2 expression inversely correlated with histopathological grade and ER positive tumors exhibited higher SOCS2 levels. Patients with high SOCS2 expression lived significantly longer (108.7 vs. 77.7 months; P = 0.015 and high SOCS2 expression proved to be an independent predictor for good prognosis (HR = 0.45, 95% CI 0.23 – 0.91, P = 0.026. In analogy to SOCS2, high IGF-I expression was an independent predictor for good prognosis in the entire patient cohort. In the subgroup of patients with lymph-node negative disease, high IGF-I was a strong predictor for favorable outcome in terms of overall survival and relapse free survival (HR = 0.075, 95% CI 0.014 – 0.388, P = 0.002. Conclusion This is the first report on the favorable prognostic value of high SOCS2 expression in primary mammary carcinomas. Furthermore a strong association of high IGF-I expression levels with good prognosis was observed especially in lymph-node negative patients. Our results suggest that high expression of the STAT5 target genes SOCS2 and IGF

  2. Cross-sectional survey: risk-averse French general practitioners are more favorable toward influenza vaccination.

    Science.gov (United States)

    Massin, Sophie; Ventelou, Bruno; Nebout, Antoine; Verger, Pierre; Pulcini, Céline

    2015-01-29

    We tested the following hypotheses: (i) risk-averse general practitioners (GPs) are more likely to be vaccinated against influenza; (ii) and risk-averse GPs recommend influenza vaccination more often to their patients. In risk-averse GPs, the perceived benefits of the vaccine and/or the perceived risks of the infectious disease might indeed outweigh the perceived risks of the vaccine. In 2010-2012, we conducted a cross-sectional survey of a nationwide French representative sample of 1136 GPs. Multivariate analyses adjusted for four stratification variables (age, gender, urban/suburban/rural practice location and annual patient consultations) and for GPs' characteristics (group/solo practice, and occasional practice of alternative medicine, e.g., homeopathy) looked for associations between their risk attitudes and self-reported vaccination behavior. Individual risk attitudes were expressed as a continuous variable, from 0 (risk-tolerant) to 10 (risk-averse). Overall, 69% of GPs reported that they were very favorable toward vaccination in general. Self-reported vaccination coverage was 78% for 2009/2010 seasonal influenza and 62% for A/H1N1 pandemic influenza. Most GPs (72%) reported recommending the pandemic influenza vaccination to at-risk young adults in 2009, but few than half (42%) to young adults not at risk. In multivariate analyses, risk-averse GPs were more often vaccinated against seasonal (marginal effect=1.3%, P=0.02) and pandemic influenza (marginal effect=1.5%, P=0.02). Risk-averse GPs recommended the pandemic influenza vaccination more often than their more risk-tolerant colleagues to patients without risk factors (marginal effect=1.7%, P=0.01), but not to their at-risk patients and were more favorable toward vaccination in general (marginal effect=1.5%, P=0.04). Individual risk attitudes may influence GPs' practices regarding influenza vaccination, both for themselves and their patients. Our results suggest that risk-averse GPs may perceive the risks

  3. Subsurface stratigraphy and uranium--vanadium favorability of the Morrison Formation, Sage Plain Area, southeastern Utah and southwestern Colorado

    International Nuclear Information System (INIS)

    Girdley, W.A.; Flook, J.E.; Harris, R.E.

    1975-08-01

    The four members of the Morrison Formation that are recognizable in the area studied are, in ascending order, the Salt Wash, Recapture, Westwater Canyon, and Brushy Basin. The Salt Wash member has the highest uranium favorability of all the Morrison strata in the area studied. An especially favorable area, in which the Salt Wash interval is thick and contains several thick sandstones, is situated on either side of the Utah-Colorado state line between Monticello, Utah, and Dove Creek, Colorado. The upper Morrison strata (Westwater Canyon and Brushy Basin members) have low uranium favorability. The Westwater Canyon member contains adequate sandstones but lacks known uranium deposits in the project area. The Brushy Basin member, although rated as having low potential, nevertheless does possess some attributes that make it worthy of further attention. The Recapture member does not contain sufficient well-developed sandstones or uranium deposits to merit its being classed as favorable for potential uranium-vanadium resources. (LK)

  4. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    Directory of Open Access Journals (Sweden)

    Conzuelo González, Viridiana Vanessa

    2009-01-01

    Full Text Available El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estudio transversal (2006-2007, en la comunidad mazahua de San Francisco Tepeolulco, Municipio de Temascalcingo; que incluyó a 85 hogares integrados por preescolares con desnutrición inscritos al programa Oportunidades. Se determinó el estado nutrición de los preescolares con indicadores antropométricos y se obtuvo el IMC de las madres de estos infantes. Se aplicó una encuesta socionutricional, incluida el recordatorio de 24 horas, y complementado con la observación participante (cualitativa. Se encontró que 83% de las madres mazahuas presentaron sobrepeso u obesidad. El estado de nutrición de los preescolares con madres con obesidad presentó un porcentaje mayor de desnutrición (76%. En la variable género, se encontró que 54% de los niños con madres con obesidad tenía baja talla. Al relacionar el nivel educativo de la madre, esta variable resultó ser estadísticamente significativa (p=0.015, donde el analfabetismo está más relacionado con la desnutrición infantil que tienen madres de bajo y/o peso normal. La elevada prevalencia de hogares conformados con preescolares con desnutrición y madres con obesidad, es un síntoma más de la pobreza en zonas indígenas en México, con bajo índice de desarrollo humano.

  5. Favoring the unfavored: Selective electrochemical nitrogen fixation using a reticular chemistry approach.

    Science.gov (United States)

    Lee, Hiang Kwee; Koh, Charlynn Sher Lin; Lee, Yih Hong; Liu, Chong; Phang, In Yee; Han, Xuemei; Tsung, Chia-Kuang; Ling, Xing Yi

    2018-03-01

    Electrochemical nitrogen-to-ammonia fixation is emerging as a sustainable strategy to tackle the hydrogen- and energy-intensive operations by Haber-Bosch process for ammonia production. However, current electrochemical nitrogen reduction reaction (NRR) progress is impeded by overwhelming competition from the hydrogen evolution reaction (HER) across all traditional NRR catalysts and the requirement for elevated temperature/pressure. We achieve both excellent NRR selectivity (~90%) and a significant boost to Faradic efficiency by 10 percentage points even at ambient operations by coating a superhydrophobic metal-organic framework (MOF) layer over the NRR electrocatalyst. Our reticular chemistry approach exploits MOF's water-repelling and molecular-concentrating effects to overcome HER-imposed bottlenecks, uncovering the unprecedented electrochemical features of NRR critical for future theoretical studies. By favoring the originally unfavored NRR, we envisage our electrocatalytic design as a starting point for high-performance nitrogen-to-ammonia electroconversion directly from water vapor-abundant air to address increasing global demand of ammonia in (bio)chemical and energy industries.

  6. Blood group antigen A type 3 expression is a favorable prognostic factor in advanced NSCLC.

    Science.gov (United States)

    Schmidt, L H; Kuemmel, A; Schliemann, C; Schulze, A; Humberg, J; Mohr, M; Görlich, D; Hartmann, W; Bröckling, S; Marra, A; Hillejan, L; Goletz, S; Karsten, U; Berdel, W E; Spieker, T; Wiewrodt, R

    2016-02-01

    Several blood group-related carbohydrate antigens are prognosis-relevant markers of tumor tissues. A type 3 (repetitive A) is a blood group antigen specific for A1 erythrocytes. Its potential expression in tumor tissues has so far not been examined. We have evaluated its expression in normal lung and in lung cancer using a novel antibody (A69-A/E8). For comparison an anti-A antibody specific to A types 1 and 2 was used, because its expression on lung cancer tissue has been previously reported to be of prognostic relevance. Resected tissue samples of 398 NSCLC patients were analyzed in immunohistochemistry using tissue microarrays. Expression of A type 3 was not observed in non-malignant lung tissues. A type 3 was expressed on tumor cells of around half of NSCLC patients of blood group A1 (ptype 1/2 antigen was observed (p=0.562), the expression of A type 3 by tumor cells indicated a highly significant favorable prognosis among advanced NSCLC patients (p=0.011) and in NSCLC patients with lymphatic spread (p=0.014). Univariate prognostic results were confirmed in a Cox proportional hazards model. In this study we present for the first time prognostic data for A type 3 antigen expression in lung cancer patients. Prospective studies should be performed to confirm the prognostic value of A type 3 expression for an improved risk stratification in NSCLC patients. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. Potential climate change favored expansion of a range limited species, Haematostaphis barteri Hook f.

    Directory of Open Access Journals (Sweden)

    Jacob Koundouonon Moutouama

    2016-12-01

    Full Text Available Understanding impact of climate change on range breadth of rare species can improve the ability to anticipate their decline or expension and take appropriate conservation measures. Haematatostaphis barteri is an agroforestry species of the Sudanian centre of endemism in Africa. We investigeted impact of climate change on range of suitable habitats for this species in Benin,using the Maximum Entropy algorithm under R software. Five environmental variables were used with the regional climate model under the new Representation Concentration Pathways (RCP. Moisture Index of the Moist Quarter and Slope variability had the greatest predictive importance for the range of suitable habitats for H. barteri. Its Potential breadth was found to be currently limited to the Atacora Mountain Chain (AMC and covers 0.51% of national territory. Climate change was projected to favor expansion of suitable habitats for H. barteri by 0.12% and 0.05%, respectively for the RCP4.5 and RCP8.5. These habitats were however mostly out of the local protected areas network. Climate change would extend range of habitats for H. barteri. Observed protection gaps suggest need for integrating this species into formal in situ, on-farm or ex situ conservation schemes.

  8. Li7(BH)5(+): a new thermodynamically favored star-shaped molecule.

    Science.gov (United States)

    Torres-Vega, Juan J; Vásquez-Espinal, Alejandro; Beltran, Maria J; Ruiz, Lina; Islas, Rafael; Tiznado, William

    2015-07-15

    The potential energy surfaces (PESs) of Lin(BH)5(n-6) systems (where n = 5, 6, and 7) were explored using the gradient embedded genetic algorithm (GEGA) program, in order to find their global minima conformations. This search predicts that the lowest-energy isomers of Li6(BH)5 and Li7(BH)5(+) contain a (BH)5(6-) pentagonal fragment, which is isoelectronic and structurally analogous to the prototypical aromatic hydrocarbon anion C5H5(-). Li7(BH)5(+), along with Li7C5(+), Li7Si5(+) and Li7Ge5(+), joins a select group of clusters that adopt a seven-peak star-shape geometry, which is favored by aromaticity in the central five-membered ring, and by the preference of Li atoms for bridging positions. The theoretical analysis of chemical bonding, based on magnetic criteria, supports the notion that electronic delocalization is an important stabilization factor in all these star-shaped clusters.

  9. Social heuristics and social roles: Intuition favors altruism for women but not for men.

    Science.gov (United States)

    Rand, David G; Brescoll, Victoria L; Everett, Jim A C; Capraro, Valerio; Barcelo, Hélène

    2016-04-01

    Are humans intuitively altruistic, or does altruism require self-control? A theory of social heuristics, whereby intuitive responses favor typically successful behaviors, suggests that the answer may depend on who you are. In particular, evidence suggests that women are expected to behave altruistically, and are punished for failing to be altruistic, to a much greater extent than men. Thus, women (but not men) may internalize altruism as their intuitive response. Indeed, a meta-analysis of 13 new experiments and 9 experiments from other groups found that promoting intuition relative to deliberation increased giving in a Dictator Game among women, but not among men (Study 1, N = 4,366). Furthermore, this effect was shown to be moderated by explicit sex role identification (Study 2, N = 1,831): the more women described themselves using traditionally masculine attributes (e.g., dominance, independence) relative to traditionally feminine attributes (e.g., warmth, tenderness), the more deliberation reduced their altruism. Our findings shed light on the connection between gender and altruism, and highlight the importance of social heuristics in human prosociality. (c) 2016 APA, all rights reserved).

  10. Hydrogen Storage Capacity of Tetrahydrofuran and Tetra-N-Butylammonium Bromide Hydrates Under Favorable Thermodynamic Conditions

    Directory of Open Access Journals (Sweden)

    Joshua T. Weissman

    2017-08-01

    Full Text Available An experimental study was conducted to evaluate the feasibility of employing binary hydrates as a medium for H2 storage. Two reagents, tetrahydrofuran (THF and tetra-n-butylammonium bromide (TBAB, which had been reported previously to have potential to form binary hydrates with H2 under favorable conditions (i.e., low pressures and high temperatures, were investigated using differential scanning calorimetry and Raman spectroscopy. A scale-up facility was employed to quantify the hydrogen storage capacity of THF binary hydrate. Gas chromatography (GC and pressure drop analyses indicated that the weight percentages of H2 in hydrate were less than 0.1%. The major conclusions of this investigation were: (1 H2 can be stored in binary hydrates at relatively modest pressures and temperatures which are probably feasible for transportation applications; and (2 the storage capacity of H2 in binary hydrate formed from aqueous solutions of THF over a concentration range extending from 2.78 to 8.34 mol % and at temperatures above 263 K and pressures below 11 MPa was <0.1 wt %.

  11. Seasonal resource conditions favor a summertime increase in North Pacific diatom-diazotroph associations.

    Science.gov (United States)

    Follett, Christopher L; Dutkiewicz, Stephanie; Karl, David M; Inomura, Keisuke; Follows, Michael J

    2018-02-15

    In the North Pacific Subtropical Gyre (NPSG), an annual pulse of sinking organic carbon is observed at 4000 m between July and August, driven by large diatoms found in association with nitrogen fixing, heterocystous, cyanobacteria: Diatom-Diazotroph Associations (DDAs). Here we ask what drives the bloom of DDAs and present a simplified trait-based model of subtropical phototroph populations driven by observed, monthly averaged, environmental characteristics. The ratio of resource supply rates favors nitrogen fixation year round. The relative fitness of DDA traits is most competitive in early summer when the mixed layer is shallow, solar irradiance is high, and phosphorus and iron are relatively abundant. Later in the season, as light intensity drops and phosphorus is depleted, the traits of small unicellular diazotrophs become more competitive. The competitive transition happens in August, at the time when the DDA export event occurs. This seasonal dynamic is maintained when embedded in a more complex, global-scale, ecological model, and provides predictions for the extent of the North Pacific DDA bloom. The model provides a parsimonious and testable hypothesis for the stimulation of DDA blooms.

  12. Preliminary study of favorability for uranium resources in Juab County, Utah

    International Nuclear Information System (INIS)

    Leedom, S.H.; Mitchell, T.P.

    1978-02-01

    The best potential for large, low-grade uranium deposits in Juab County is in the hydrothermally altered vitric tuffs of Pliocene age. The lateral extent of the altered tuffs may be determined by subsurface studies around the perimeter of the volcanic centers in the Thomas Range and the Honeycomb Hills. Because the ring-fracture zone associated with collapse of the Thomas caldera was a major control for hydrothermal uranium deposits, delineation of the northern and eastern positions of the ring-fracture zone is critical in defining favorable areas for uranium deposits. A small, medium-grade ore deposit in tuffaceous sand of Pliocene age at the Yellow Chief mine in Dugway Dell is unique in origin, and the probability of discovering another deposit of this type is low. A deposit of this type may be present under alluvial cover in the northwestern Drum Mountains along the southern extension of the ring-fracture zone of the Thomas caldera. Festoonlike iron oxide structures and uranium deposition within permeable sandstone horizons indicate that the Yellow Chief deposit was formed by recent ground-water circulation. Granitic intrusive rocks in the Deep Creek Range and in Desert Mountain contain isolated epigenetic vein-type deposits. These rocks could be a source of arkosic sediments buried in adjacent valleys. The Pleistocene lacustrine sediments and playa lake brines may contain concentrations of uranium leached from uranium-rich rocks

  13. Balanced bilinguals favor lexical processing in their opaque language and conversion system in their shallow language.

    Science.gov (United States)

    Buetler, Karin A; de León Rodríguez, Diego; Laganaro, Marina; Müri, René; Nyffeler, Thomas; Spierer, Lucas; Annoni, Jean-Marie

    2015-11-01

    Referred to as orthographic depth, the degree of consistency of grapheme/phoneme correspondences varies across languages from high in shallow orthographies to low in deep orthographies. The present study investigates the impact of orthographic depth on reading route by analyzing evoked potentials to words in a deep (French) and shallow (German) language presented to highly proficient bilinguals. ERP analyses to German and French words revealed significant topographic modulations 240-280 ms post-stimulus onset, indicative of distinct brain networks engaged in reading over this time window. Source estimations revealed that these effects stemmed from modulations of left insular, inferior frontal and dorsolateral regions (German>French) previously associated to phonological processing. Our results show that reading in a shallow language was associated to a stronger engagement of phonological pathways than reading in a deep language. Thus, the lexical pathways favored in word reading are reinforced by phonological networks more strongly in the shallow than deep orthography. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Evolution of learning in fluctuating environments: when selection favors both social and exploratory individual learning.

    Science.gov (United States)

    Borenstein, Elhanan; Feldman, Marcus W; Aoki, Kenichi

    2008-03-01

    Cumulative cultural change requires organisms that are capable of both exploratory individual learning and faithful social learning. In our model, an organism's phenotype is initially determined innately (by its genotypic value) or by social learning (copying a phenotype from the parental generation), and then may or may not be modified by individual learning (exploration around the initial phenotype). The environment alternates periodically between two states, each defined as a certain range of phenotypes that can survive. These states may overlap, in which case the same phenotype can survive in both states, or they may not. We find that a joint social and exploratory individual learning strategy-the strategy that supports cumulative culture-is likely to spread when the environmental states do not overlap. In particular, when the environmental states are contiguous and mutation is allowed among the genotypic values, this strategy will spread in either moderately or highly stable environments, depending on the exact nature of the individual learning applied. On the other hand, natural selection often favors a social learning strategy without exploration when the environmental states overlap. We find only partial support for the "consensus" view, which holds that individual learning, social learning, and innate determination of behavior will evolve at short, intermediate, and long environmental periodicities, respectively.

  15. Stereotactic ablative radiotherapy for small lung tumors with a moderate dose. Favorable results and low toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Duncker-Rohr, V.; Nestle, U. [Universitaetsklinikum Freiburg (Germany); Momm, F. [Ortenau Klinikum Offenburg (Germany)] [and others

    2013-01-15

    Background: Stereotactic ablative body radiotherapy (SBRT, SABR) is being increasingly applied because of its high local efficacy, e.g., for small lung tumors. However, the optimum dosage is still under discussion. Here, we report data on 45 lung lesions [non-small cell lung cancer (NSCLC) or metastases] in 39 patients treated between 2009 and 2010 by SABR. Patients and methods: SABR was performed with total doses of 35 Gy (5 fractions) or 37.5 Gy (3 fractions) prescribed to the 60% isodose line encompassing the planning target volume. Three-monthly follow-up CT scans were supplemented by FDG-PET/CT if clinically indicated. Results: The median follow-up was 17 months. Local progression-free survival rates were 90.5% (all patients), 95.0% (NSCLC), and 81.8% (metastases) at 1 year. At 2 years, the respective local progression-free survival rates were 80.5%, 95.0%, and 59.7%. Overall survival rates were 71.1% (all patients), 65.4% (NSCLC), and 83.3% (metastases) at 1 year. Overall survival rates at 2 years were 52.7%, 45.9%, and 66.7%, respectively. Acute side effects were mild. Conclusion: With the moderate dose schedule used, well-tolerated SABR led to favorable local tumor control as in other published series. Standardization in reporting the dose prescription for SABR is needed to allow comparison of different series in order to determine optimum dosage. (orig.)

  16. The Norwood procedure: in favor of the RV-PA conduit.

    Science.gov (United States)

    Barron, David J

    2013-01-01

    Evolution of the Norwood procedure has culminated in there currently being three treatment strategies available for initial management: the 'classical' Norwood (utilizing a Blalock-Taussig shunt), the Norwood with right-ventricle to pulmonary artery (RV-PA) conduit, and the 'hybrid' Norwood procedure utilizing bilateral pulmonary artery banding and ductal stenting. Each variant has its potential advantages and disadvantages, and this paper looks to examine the evidence in favor of each strategy, with emphasis on the supportive data for the RV-PA conduit. The 'classical' procedure has the benefit of the greatest accumulated surgical experience and avoids any incision into the ventricle. However, the diastolic run-off of the Blalock-Taussig shunt can cause hemodynamic instability and unpredictable coronary steal phenomenon. The RV-PA conduit has the advantage of maintaining diastolic pressure with a more stable postoperative course, but at the cost of a ventriculotomy that may have detrimental long-term sequelae. The 'hybrid' procedure has the advantage of avoiding cardiopulmonary bypass, but does not always secure coronary blood flow and has a high inter-stage morbidity and reintervention rate. The evidence shows that each technique may have its place in future management, and that treatment algorithms could emerge that direct the choice of procedure for specific patient groups. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. FLARE STARS—A FAVORABLE OBJECT FOR STUDYING MECHANISMS OF NONTHERMAL ASTROPHYSICAL PHENOMENA

    Energy Technology Data Exchange (ETDEWEB)

    Oks, E. [Physics Department, 206 Allison Lab., Auburn University, Auburn, AL 36849 (United States); Gershberg, R. E. [Crimean Astrophysical Observatory, Nauchny, Bakhchisaray region, Crimea, 298409 (Russian Federation)

    2016-03-01

    We present a spectroscopic method for diagnosing a low-frequency electrostatic plasma turbulence (LEPT) in plasmas of flare stars. This method had been previously developed by one of us and successfully applied to diagnosing the LEPT in solar flares. In distinction to our previous applications of the method, here we use the latest advances in the theory of the Stark broadening of hydrogen spectral lines. By analyzing observed emission Balmer lines, we show that it is very likely that the LEPT was developed in several flares of AD Leo, as well as in one flare of EV Lac. We found the LEPT (though of different field strengths) both in the explosive/impulsive phase and at the phase of the maximum, as well as at the gradual phase of the stellar flares. While for solar flares our method allows diagnosing the LEPT only in the most powerful flares, for the flare stars it seems that the method allows revealing the LEPT practically in every flare. It should be important to obtain new and better spectrograms of stellar flares, allowing their analysis by the method outlined in the present paper. This can be the most favorable way to the detailed understanding of the nature of nonthermal astrophysical phenomena.

  18. Chlorophyll a is a favorable substrate for Chlamydomonas Mg-dechelatase encoded by STAY-GREEN.

    Science.gov (United States)

    Matsuda, Kaori; Shimoda, Yousuke; Tanaka, Ayumi; Ito, Hisashi

    2016-12-01

    Mg removal from chlorophyll by Mg-dechelatase is the first step of chlorophyll degradation. Recent studies showed that in Arabidopsis, Stay Green (SGR) encodes Mg-dechelatase. Though the Escherichia coli expression system is advantageous for investigating the properties of Mg-dechelatase, Arabidopsis Mg-dechelatase is not successfully expressed in E. coli. Chlamydomonas reinhardtii SGR (CrSGR) has a long, hydrophilic tail, suggesting that active CrSGR can be expressed in E. coli. After the incubation of chlorophyll a with CrSGR expressed in E. coli, pheophytin a accumulated, indicating that active CrSGR was expressed in E. coli. Substrate specificity of CrSGR against chlorophyll b and an intermediate molecule of the chlorophyll b degradation pathway was examined. CrSGR exhibited no activity against chlorophyll b and low activity against 7-hydroxymethyl chlorophyll a, consistent with the fact that chlorophyll b is degraded only after conversion to chlorophyll a. CrSGR exhibited low activity against divinyl chlorophyll a and chlorophyll a', and no activity against chlorophyllide a, protochlorophyll a, chlorophyll c 2 , and Zn-chlorophyll a. These observations indicate that chlorophyll a is the most favorable substrate for CrSGR. When CrSGR was expressed in Arabidopsis cells, the chlorophyll content decreased, further confirming that SGR has Mg-dechelating activity in chloroplasts. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  19. Renal capsule for augmentation cystoplasty in canine model: a favorable biomaterial?

    Directory of Open Access Journals (Sweden)

    Mehdi Salehipour

    2016-04-01

    Full Text Available ABSTRACT Purpose: To evaluate effectiveness of canine renal capsule for augmentation cystoplasty. Materials and Methods: Ten adult dogs participated in this study. After induction of anesthesia each animal underwent bed side urodynamic study, bladder capacity and bladder pressure was recorded. Then via mid line incision abdominal cavity was entered, right kidney was identified and its capsule was dissected. Bladder augmentation was done by anastomosing the renal capsule to the bladder. After 6 months bed side urodynamic study was performed again and changes in bladder volume and pressure were recorded. Then the animals were sacrificed and the augmented bladders were sent for histopathology evaluation. Results: Mean maximum anatomic bladder capacity before cystoplasty was 334.00±11.40cc which increased to 488.00±14.83cc post-operatively (p=0.039. Mean anatomic bladder pressure before cystoplasty was 19.00±1.58cmH2O which decreased to 12.60±1.14cmH2O post-operatively (p=0.039. Histopathology evaluation revealed epithelialization of the renal capsule with urothelium without evidence of fibrosis, collagen deposits or contracture. Conclusions: Our data shows that renal capsule is a favorable biomaterial for bladder augmentation in a canine model.

  20. Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Zhu A. Wang

    2014-09-01

    Full Text Available The identification of cell types of origin for cancer has important implications for tumor stratification and personalized treatment. For prostate cancer, the cell of origin has been intensively studied, but it has remained unclear whether basal or luminal epithelial cells, or both, represent cells of origin under physiological conditions in vivo. Here, we use a novel lineage-tracing strategy to assess the cell of origin in a diverse range of mouse models, including Nkx3.1+/−; Pten+/−, Pten+/−, Hi-Myc, and TRAMP mice, as well as a hormonal carcinogenesis model. Our results show that luminal cells are consistently the observed cell of origin for each model in situ; however, explanted basal cells from these mice can generate tumors in grafts. Consequently, we propose that luminal cells are favored as cells of origin in many contexts, whereas basal cells only give rise to tumors after differentiation into luminal cells.

  1. Arguments in Favor of Moving to a Sustainable Business Model in the Apiary Industry

    Directory of Open Access Journals (Sweden)

    Panța Nancy Diana

    2017-12-01

    Full Text Available Today’s society faces major challenges in meeting future global food demands and solving biodiversity loss, and it quickly needs to find ways in addressing these issues. The places to look for solutions come from the economic sectors that employ the most powerful pressure on these issues such as agriculture. Apiculture, as a branch of agriculture is being more and more recognized as sustaining human life and contributing to sustainability. However, the sector records a progressive decline of honey bees. Therefore, a rapid restructuring needs to take place in agricultural markets, in general, as well as in apiary agribusinesses. Although important, technological progress is insufficient in providing the necessary changes to achieve long-term economic, social and environmental sustainability, which should be considered both within and between generations. Consequently, sustainable business models encourage sustainable development through a triple bottom line approach and provide an analytical tool for firms into assessing the different aspects that are combined in order to create value. Since literature has paid little attention to the sustainable development in the apiary agribusiness, the present paper aims to link the two using a business model perspective and bring arguments in favor of moving to a sustainable business model.

  2. Natural History of Untreated Prostate Specific Antigen Radiorecurrent Prostate Cancer in Men with Favorable Prognostic Indicators

    Directory of Open Access Journals (Sweden)

    Neil E. Martin

    2014-01-01

    Full Text Available Background and Purpose. Life expectancy data could identify men with favorable post-radiation prostate-specific antigen (PSA failure kinetics unlikely to require androgen deprivation therapy (ADT. Materials and Methods. Of 206 men with unfavorable-risk prostate cancer in a randomized trial of radiation versus radiation and ADT, 53 experienced a PSA failure and were followed without salvage ADT. Comorbidity, age and established prognostic factors were assessed for relationship to death using Cox regression analyses. Results. The median age at failure, interval to PSA failure, and PSA doubling time were 76.6 years (interquartile range [IQR]: 71.8–79.3, 49.1 months (IQR: 37.7–87.4, and 25 months (IQR: 13.1–42.8, respectively. After a median follow up of 4.0 years following PSA failure, 45% of men had died, none from prostate cancer and no one had developed metastases. Both increasing age at PSA failure (HR: 1.14; 95% CI: 1.03–1.25; P=0.008 and the presence of moderate to severe comorbidity (HR: 12.5; 95% CI: 3.81–41.0; P2 years following post-radiation PSA failure appear to be good candidates for observation without ADT intervention.

  3. Anticipated detection of favorable periods for wind energy production by means of information theory

    Science.gov (United States)

    Vogel, Eugenio; Saravia, Gonzalo; Kobe, Sigismund; Schumann, Rolf; Schuster, Rolf

    Managing the electric power produced by different sources requires mixing the different response times they present. Thus, for instance, coal burning presents large time lags until operational conditions are reached while hydroelectric generation can react in a matter of some seconds or few minutes to reach the desired productivity. Wind energy production (WEP) can be instantaneously fed to the network to save fuels with low thermal inertia (gas burning for instance), but this source presents sudden variations within few hours. We report here for the first time a method based on information theory to handle WEP. This method has been successful in detecting dynamical changes in magnetic transitions and variations of stock markets. An algorithm called wlzip based on information recognition is used to recognize the information content of a time series. We make use of publically available energy data in Germany to simulate real applications. After a calibration process the system can recognize directly on the WEP data the onset of favorable periods of a desired strength. Optimization can lead to a few hours of anticipation which is enough to control the mixture of WEP with other energy sources, thus saving fuels.

  4. Cabibbo-Kobayashi-Maskawa-favored B decays to a scalar meson and a D meson

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Zhi-Tian; Li, Ying [Yantai University, Department of Physics, Yantai (China); Liu, Xin [Jiangsu Normal University, School of Physics and Electronic Engineering, Xuzhou (China)

    2017-12-15

    In this work, we attempt to study the Cabibbo-Kobayashi-Maskawa-favored B → anti DS (''S'' denoting the scalar meson) decays within the perturbative QCD approach at the leading order and the leading power. Although the light scalar mesons are widely perceived as primarily the four-quark bound states, in practice it is hard for us to make quantitative predictions based on the four-quark picture for light scalars. Hence, we calculate the decays with light scalars in the two-quark model. For the decays with scalar mesons above 1 GeV, we have explored two possible scenarios, depending on whether the light scalars are treated as the lowest lying q anti q states or four-quark particles. In total, we calculated the branching fractions of 72 decay modes, and most of them are in the range 10{sup -4}-10{sup -7}, which are measurable in the on-going LHCb experiment and the forthcoming Belle-II experiment. Moreover, since in the standard model these decays occur only through tree operators and have no CP asymmetries, any deviation will be a signal of new physics beyond the standard model. Despite large uncertainties induced by nonperturbative parameters and corrections of high order and high power, our results and discussions will be useful for the on-going LHCb and the forthcoming Belle-II experiments. (orig.)

  5. Epilepsia de la infancia con paroxismos occipitales

    Directory of Open Access Journals (Sweden)

    Albia Pozo Alonso

    1999-09-01

    Full Text Available Se reporta que la epilepsia de la infancia con paroxismos occipitales constituye un síndrome epiléptico muy bien definido; se incluye en el grupo de las epilepsias idiopáticas relacionadas con localización. Los ataques comienzan habitualmente con síntomas visuales, en ocasiones seguidos por ataques hemiclónicos, parciales complejos y tónicoclónicos generalizados. El electroencefalograma interictal muestra complejos de puntaonda de localización occipital y temporal posterior que desaparecen con la apertura de los ojos. Se presenta una paciente de 8 años de edad que reúne los criterios clínicos y electroencefalográficos de la epilepsia de la infancia con paroxismos occipitales y se enfatiza en la evolución supuestamente benigna de dicho síndrome.Is is reported that epilepsy of childhood with occipital paroxysms is an epileptic syndrome that is well defined. It is included in the group of related idiopathic epilepsies with localization. Seizures habitually begin with visual symptoms, which are ocassionally followed by hemiclonic, complex partial, and generalized tonicclonic seizures. The interictal EEG shows spike-wave complexes of occipital and temporal posterior localization that are suppressed by eye opening. A patient aged 8 in whom the clinical and electroencephalographic criteria of epilepsy of childhood with occipital paroxysms are present is studied in this paper. Emphasis is made on the apparently benign evolution of this syndrome.

  6. MOTRICIDAD EN UN GRUPO DE PERSONAS CON NECESIDADES EDUCATIVAS ESPECIALES

    Directory of Open Access Journals (Sweden)

    P. Linares

    2010-09-01

    Full Text Available

    RESUMEN

    Aunque va incrementándose la literatura sobre una materia tan incipiente como la “Actividad Motriz Adaptada”, aún son escasos en nuestro país los estudios que abordan científicamente este tema. Así pues, en este artículo se presenta un trabajo de investigación basado en la actividad motriz, y que fue llevado a cabo con un alumnado que tiene necesidades educativas especiales.
    Siendo el propósito del presente estudio, el valorar los niveles motor y cognitivo-motriz alcanzados por un grupo de alumnos/as con discapacidad psicofísica, tras intervenir con un programa de actividad motriz adaptada.
    La programación estuvo enmarcada dentro de la reforma del Sistema educativo, y basada en las directrices que establece el MEC (1995 para el alumnado escolarizado en Centros de Educación Especial.
    El diseño experimental utilizado fue de tipo “intrasujeto” con medidas pretest y postest. Las variables dependientes estudiadas fueron la edad motriz y el nivel cognitivo-motor, y la independiente el propio Programa de Actividad Motriz Adaptada.
    Los resultados obtenidos fueron significativos en favor de un incremento de los aspectos motores y cognitivomotrices de todos los sujetos. Lo que nos permite concluir la importancia que tiene la Motricidad para este alumnado con necesidades educativas especiales permanentes.
    PALABRAS CLAVE: Necesidades educativas especiales, niños/as, aspectos cognitivo-motrices, adaptación curricular significativa, actividad motriz adaptada

     

    ABSTRACT

    Although literature about an incipient subject like “Adapted Motor Activity” increases day by day, the studies which approach in a scientific way this subject are not many in our country. So, in this article a research based on motor activity is

  7. Qualidade de vida de pacientes com câncer hematológico em tratamento quimioterápico Calidad de vida de pacientes con cáncer hematológico en tratamiento quimioterápico Quality of life in hematologic oncology patients undergoing chemotherapy

    Directory of Open Access Journals (Sweden)

    Viviane Andrade

    2013-04-01

    Full Text Available Estudo descritivo, transversal desenvolvido com objetivo de associar aspectos socio demográficos e clínicos aos domínios de qualidade de vida relacionada à saúde (QVRS, para avaliar pacientes onco-hematológicos submetidos à quimioterapia. Na coleta de dados utilizou-se um instrumento sociodemográfico e clínico e o European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C-30. A amostra foi constituída de 32 pacientes, sendo oito (25% com diagnóstico de linfoma de Hodgkin, nove (28,12% linfoma não Hodgkin e 15 (46,87% leucemia. Os dados foram analisados pelo software Statistical Package for Social Science (SPSS. O QLQ-C-30 mostrou média das funções física, cognitiva, emocional, social e desempenho de papel de 54,81 a 41,18, demonstrando um nível pouco satisfatório. Nas escalas de sintomas, houve predomínio de fadiga média 64,57 seguida de insônia (56,90 e perda de apetite (50,71. Esses sintomas interferiram nas funções físicas, emocionais e cognitivas demonstrando que efeitos colaterais do tratamento influenciam negativamente na QVRS dos pacientes.Estudio descriptivo, transversal, objetivando asociar aspectos sociodemográficos y clínicos a dominios de calidad de vida relacionada a la salud (QVRS, para evaluar pacientes oncohematológicos sometidos a quimioterapia. Datos recolectados mediante instrumento sociodemográfico-clínico y European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C-30. Muestra de 32 pacientes, ocho de ellos (25% con diagnóstico de linfoma de Hodgkin, nueve (28,12% con linfoma no Hodgkin y 15 (46,87% con leucemia. Los datos se analizaron con software Statistical Package for Social Science (SPSS. El QLQ-C-30 expresó promedio de funciones física, cognitiva, emocional, social y desempeño de papel de 54,81 a 41,18, mostrando nivel poco satisfactorio. En las escalas de síntomas hubo predominio de fatiga promedio

  8. Aspectos Psicosociales Relacionados con el TEPT en Pacientes con Cáncer de Mama

    OpenAIRE

    Hernández Moreno, Fresia Paloma; Landero Hernández, René

    2015-01-01

    El objetivo del estudio fue analizar la relación del estrés, la depresión y las estrategias de afrontamiento con el Trastorno de Estrés Postraumático (TEPT) en una muestra de pacientes con cáncer de mama. Se realizó con una muestra no probabilística de 52 mujeres con cáncer de mama. Se encontró una relación entre TEPT y estrés (r= .344, p= .014), TEPT y depresión (rs=.346, p= .013). El TEPT correlacionó con evitación cognitiva (r= .437, p= .001), TEPT y desesperanza (rs= .437, p= .001) y TEPT...

  9. Desarrollo de aleaciones multifuncionales con base titanio

    OpenAIRE

    Pareja, Ramiro

    2007-01-01

    El Laboratorio de Materiales Nano-estructurados y Multifuncionales del Departamento de Física de la Universidad Carlos III de Madrid se dedica al desarrollo, procesado y caracterización de aleaciones con propiedades mejores que las preparadas por métodos convencionales. La mejora de las propiedades se consigue produciendo las aleaciones con un tamaño de grano nanométrico o ultrafino, o introduciendo una dispersión de nano-partículas de óxido en la matriz. El grupo está interesado en algún tip...

  10. TIROTOXICOSIS GESTACIONAL: PATOLOGIA CON RIESGO VITAL

    OpenAIRE

    Valdés R.,Enrique; Pilasi M.,Carlos; Núñez U.,Tatiana

    2003-01-01

    Se presenta un caso clínico con diagnóstico final de Tirotoxicosis gestacional que debuta con una complicación excepcional, insuficiencia cardíaca congestiva e hipertensión pulmonar severa. Se presenta la experiencia del Hospital Clínico de la Universidad de Chile, proponiendo que su diagnóstico y tratamiento oportunos son la base del pronóstico de esta patología de riesgo vital para el binomio madre-hijo

  11. Amplificadores con transistores. Estudio y dimensionado

    OpenAIRE

    Lubiano García, Adrián

    2017-01-01

    Este trabajo es un estudio de las distintas configuraciones de los amplificadores con transistores vistos en la asignatura de Electrónica Analógica del tercer curso del Grado en Ingeniería en Electrónica Industrial y Automática de la Escuela de Ingenierías Industriales de la Universidad de Valladolid. En este trabajo se mostrarán los pasos seguidos en la creación de una aplicación con Visual Basic para la realización de los ejercicios de las distintas configuraciones, así...

  12. Galaxias australes con núcleo doble

    Science.gov (United States)

    Gimeno, G.; Díaz, R.; Carranza, G.

    Se estudia una muestra de galaxias australes con núcleo doble a partir de una búsqueda extensiva en la literatura. Se analizan las características morfológicas, fotométricas y espectroscópicas de la muestra. Para algunas galaxias se han realizado observaciones con el espectrógrafo multifunción (EMF) de la Estación Astrofísica de Bosque Alegre a partir de las cuales se determinaron parámetros cinemáticos.

  13. Nuclear morphometry and prognosis in favorable histology Wilms' tumor: A prospective reevaluation.

    Science.gov (United States)

    Breslow, N E; Partin, A W; Lee, B R; Guthrie, K A; Beckwith, J B; Green, D M

    1999-07-01

    This study was designed to evaluate the ability of a previously published nuclear morphometry discriminant function to predict disease-free survival in patients with Wilms' tumor. We identified 218 patients with stage I-IV Wilms' tumor of favorable histology who were entered onto the National Wilms' Tumor Study (NWTS) between January 1, 1990 and April 15, 1994. The nuclear morphometry score was calculated for each patient as follows: MV(f) = (0.02 x AGE) + (1.17 x SNRF) + (90.6 x LEFD) - 94, with AGE denoting age at diagnosis in months, SNRF the skewness of the nuclear roundness factor, and LEFD the lowest value of nuclear ellipticity as measured by the feret diameter method. Relative risks of relapse were estimated for the total score and for each of its components. Sensitivity and specificity were determined for the criterion of "MV(f) is greater than -0.35" as a predictor of relapse. By contrast with previously published results, neither the SNRF nor the LEFD made any contribution to the prediction of disease-free survival. Sensitivity and specificity of the criterion of "MV(f) is greater than -0.35" were 71% and 56%, respectively. Re-evaluation of a published nuclear morphometry score showed that it did not predict disease-free survival in patients with Wilms' tumor. The earlier study very likely overestimated the predictive power of nuclear morphometry by using the same data set both to develop the score and to evaluate its properties. Because of the huge number of combinations of nuclear morphometry measurements that may enter into the multivariate discriminant function, use of appropriate statistical methods is essential to estimate accurately the sensitivity and specificity.

  14. Resection of ictal high-frequency oscillations leads to favorable surgical outcome in pediatric epilepsy

    Science.gov (United States)

    Fujiwara, Hisako; Greiner, Hansel M.; Lee, Ki Hyeong; Holland-Bouley, Katherine D.; Seo, Joo Hee; Arthur, Todd; Mangano, Francesco T.; Leach, James L.; Rose, Douglas F.

    2012-01-01

    Summary Purpose Intracranial electroencephalography (EEG) is performed as part of an epilepsy surgery evaluation when noninvasive tests are incongruent or the putative seizure-onset zone is near eloquent cortex. Determining the seizure-onset zone using intracranial EEG has been conventionally based on identification of specific ictal patterns with visual inspection. High-frequency oscillations (HFOs, >80 Hz) have been recognized recently as highly correlated with the epileptogenic zone. However, HFOs can be difficult to detect because of their low amplitude. Therefore, the prevalence of ictal HFOs and their role in localization of epileptogenic zone on intracranial EEG are unknown. Methods We identified 48 patients who underwent surgical treatment after the surgical evaluation with intracranial EEG, and 44 patients met criteria for this retrospective study. Results were not used in surgical decision making. Intracranial EEG recordings were collected with a sampling rate of 2,000 Hz. Recordings were first inspected visually to determine ictal onset and then analyzed further with time-frequency analysis. Forty-one (93%) of 44 patients had ictal HFOs determined with time-frequency analysis of intracranial EEG. Key Findings Twenty-two (54%) of the 41 patients with ictal HFOs had complete resection of HFO regions, regardless of frequency bands. Complete resection of HFOs (n = 22) resulted in a seizure-free outcome in 18 (82%) of 22 patients, significantly higher than the seizure-free outcome with incomplete HFO resection (4/19, 21%). Significance Our study shows that ictal HFOs are commonly found with intracranial EEG in our population largely of children with cortical dysplasia, and have localizing value. The use of ictal HFOs may add more promising information compared to interictal HFOs because of the evidence of ictal propagation and followed by clinical aspect of seizures. Complete resection of HFOs is a favorable prognostic indicator for surgical outcome. PMID

  15. Starch and starch hydrolysates are favorable carbon sources for bifidobacteria in the human gut.

    Science.gov (United States)

    Liu, Songling; Ren, Fazheng; Zhao, Liang; Jiang, Lu; Hao, Yanling; Jin, Junhua; Zhang, Ming; Guo, Huiyuan; Lei, Xingen; Sun, Erna; Liu, Hongna

    2015-03-01

    Bifidobacteria are key commensals in human gut, and their abundance is associated with the health of their hosts. Although they are dominant in infant gut, their number becomes lower in adult gut. The changes of the diet are considered to be main reason for this difference. Large amounts of whole-genomic sequence data of bifidobacteria make it possible to elucidate the genetic interpretation of their adaptation to the nutrient environment. Among the nutrients in human gut, starch is a highly fermentable substrate and can exert beneficial effects by increasing bifidobacteria and/or being fermented to short chain fatty acids. In order to determine the potential substrate preference of bifidobacteria, we compared the glycoside hydrolase (GH) profiles of a pooled-bifidobacterial genome (PBG) with a representative microbiome (RM) of the human gut. In bifidobacterial genomes, only 15% of GHs contained signal peptides, suggesting their weakness in utilization of complex carbohydrate, such as plant cell wall polysaccharides. However, compared with other intestinal bacteria, bifidobacteiral genomes encoded more GH genes for degrading starch and starch hydrolysates, indicating that they have genetic advantages in utilizing these substrates. Bifidobacterium longum subsp. longum BBMN68 isolated from centenarian's faeces was used as a model strain to further investigate the carbohydrate utilization. The pathway for degrading starch and starch hydrolysates was the only complete pathway for complex carbohydrates in human gut. It is noteworthy that all of the GH genes for degrading starch and starch hydrolysates in the BBMN68 genome were conserved in all studied bifidobacterial strains. The in silico analyses of BBMN68 were further confirmed by growth experiments, proteomic and real-time quantitative PCR (RT-PCR) analyses. Our results demonstrated that starch and starch hydrolysates were the most universal and favorable carbon sources for bifidobacteria. The low amount of these

  16. α-Amylase in Vaginal Fluid: Association With Conditions Favorable to Dominance of Lactobacillus.

    Science.gov (United States)

    Nasioudis, Dimitrios; Beghini, Joziani; Bongiovanni, Ann Marie; Giraldo, Paulo C; Linhares, Iara M; Witkin, Steven S

    2015-11-01

    Vaginal glycogen is degraded by host α-amylase and then converted to lactic acid by Lactobacilli. This maintains the vaginal pH at ≤4.5 and prevents growth of other bacteria. Therefore, host α-amylase activity may promote dominance of Lactobacilli. We evaluated whether the α-amylase level in vaginal fluid is altered in women with bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) and whether its concentration was associated with levels of lactic acid isomers and host mediators. Vaginal fluid was obtained from 43 women with BV, 50 women with VVC, and 62 women with no vulvovaginal disorders. Vaginal fluid concentrations of α-amylase, secretory leukocyte protease inhibitor (SLPI), hyaluronan, hyaluronidase-1, β-defensin, and elafin were measured by enzyme-linked immunosorbent assay (ELISA). Vaginal concentrations of neutrophil gelatinase-associated lipocalin (NGAL), matrix metalloproteinase (MMP) 8, and d- and l-lactic acid levels in these patients were previously reported. The median vaginal fluid α-amylase level was 1.83 mU/mL in control women, 1.45 mU/mL in women with VVC, and 1.07 mU/mL in women with BV. Vaginal levels of α-amylase were correlated with d-lactic acid (P = .003) but not with l-lactic acid (P > .05) and with SLPI (P vaginal lumen by hyaluronidase-1 and MMP-8 may increase glycogen availability and promote α-amylase activity. The subsequent enhanced availability of glycogen breakdown products would favor proliferation of Lactobacilli, the primary producers of d-lactic acid in the vagina. Concomitant production of NGAL and SLPI would retard growth of BV-related bacteria. © The Author(s) 2015.

  17. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol.

    Science.gov (United States)

    Erlund, Iris; Koli, Raika; Alfthan, Georg; Marniemi, Jukka; Puukka, Pauli; Mustonen, Pirjo; Mattila, Pirjo; Jula, Antti

    2008-02-01

    Berries are a particularly rich source of polyphenols. They also contain other bioactive substances, such as vitamin C. Previous studies indicated that the consumption of polyphenol-rich foods (eg, cocoa, tea, and red wine) may induce beneficial changes in pathways related to cardiovascular health. Whether the consumption of berries has similar effects is unknown. We aimed to investigate the effects of berry consumption on hemostatic function, serum lipids, and blood pressure (BP). Middle-aged unmedicated subjects (n = 72) with cardiovascular risk factors consumed moderate amounts of berry or control products for 8 wk in a single-blind, randomized, placebo-controlled intervention trial. Berry consumption inhibited platelet function as measured with a platelet function analyzer (using collagen and ADP as platelet activator) [changes: 11% and -1.4% in the berry and control groups, respectively; P = 0.018, analysis of covariance (ANCOVA)]. Plasma biomarkers of platelet activation, coagulation, and fibrinolysis did not change during the intervention. Serum HDL-cholesterol concentrations increased significantly more (P = 0.006, ANCOVA) in the berry than in the control group (5.2% and 0.6%, respectively), but total cholesterol and triacylglycerol remained unchanged. Systolic BP decreased significantly (P = 0.050, ANCOVA); the decrease mostly occurred in subjects with high baseline BP (7.3 mm Hg in highest tertile; P = 0.024, ANCOVA). Polyphenol and vitamin C concentrations in plasma increased, whereas other nutritional biomarkers (ie, folate, tocopherols, sodium, and potassium) were unaffected. The consumption of moderate amounts of berries resulted in favorable changes in platelet function, HDL cholesterol, and BP. The results indicate that regular consumption of berries may play a role in the prevention of cardiovascular disease.

  18. Factors favorable to frequent extreme precipitation in the upper Yangtze River Valley

    Science.gov (United States)

    Tian, Baoqiang; Fan, Ke

    2013-08-01

    Extreme precipitation events in the upper Yangtze River Valley (YRV) have recently become an increasingly important focus in China because they often cause droughts and floods. Unfortunately, little is known about the climate processes responsible for these events. This paper investigates factors favorable to frequent extreme precipitation events in the upper YRV. Our results reveal that a weakened South China Sea summer monsoon trough, intensified Eurasian-Pacific blocking highs, an intensified South Asian High, a southward subtropical westerly jet and an intensified Western North Pacific Subtropical High (WNPSH) increase atmospheric instability and enhance the convergence of moisture over the upper YRV, which result in more extreme precipitation events. The snow depth over the eastern Tibetan Plateau (TP) in winter and sea surface temperature anomalies (SSTAs) over three key regions in summer are important external forcing factors in the atmospheric circulation anomalies. Deep snow on the Tibetan Plateau in winter can weaken the subsequent East Asian summer monsoon circulation above by increasing the soil moisture content in summer and weakening the land-sea thermal contrast over East Asia. The positive SSTA in the western North Pacific may affect southwestward extension of the WNPSH and the blocking high over northeastern Asia by arousing the East Asian-Pacific pattern. The positive SSTA in the North Atlantic can affect extreme precipitation event frequency in the upper YRV via a wave train pattern along the westerly jet between the North Atlantic and East Asia. A tripolar pattern from west to east over the Indian Ocean can strengthen moisture transport by enhancing Somali cross-equatorial flow.

  19. Aquatic pollution may favor the success of the invasive species A. franciscana

    International Nuclear Information System (INIS)

    Varó, I.; Redón, S.; Garcia-Roger, E.M.; Amat, F.; Guinot, D.; Serrano, R.; Navarro, J.C.

    2015-01-01

    Highlights: • Artemia species display an elevated tolerance to high ranges of chlorpyrifos. • A. franciscana survived better and its fecundity was less affected by chlorpyrifos. • The higher fecundity of A. franciscana is a selective advantage in colonization processes. • Higher survival and biological fitness in A. franciscana indicate out-competitive advantages. - Abstract: The genus Artemia consists of several bisexual and parthenogenetic sibling species. One of them, A. franciscana, originally restricted to the New World, becomes invasive when introduced into ecosystems out of its natural range of distribution. Invasiveness is anthropically favored by the use of cryptobiotic eggs in the aquaculture and pet trade. The mechanisms of out-competition of the autochthonous Artemia by the invader are still poorly understood. Ecological fitness may play a pivotal role, but other underlying biotic and abiotic factors may contribute. Since the presence of toxicants in hypersaline aquatic ecosystems has been documented, our aim here is to study the potential role of an organophosphate pesticide, chlorpyrifos, in a congeneric mechanism of competition between the bisexual A. franciscana (AF), and one of the Old World parthenogenetic siblings, A. parthenogenetica (PD). For this purpose we carried out life table experiments with both species, under different concentrations of the toxicant (0.1, 1 and 5 μg/l), and analyzed the cholinesterase inhibition at different developmental stages. The results evidence that both, AF and PD, showed an elevated tolerance to high ranges of chlorpyrifos, but AF survived better and its fecundity was less affected by the exposure to the pesticide than that of PD. The higher fecundity of AF is a selective advantage in colonization processes leading to its establishment as NIS. Besides, under the potential selective pressure of abiotic factors, such as the presence of toxicants, its higher resistance in terms of survival and biological

  20. Aquatic pollution may favor the success of the invasive species A. franciscana

    Energy Technology Data Exchange (ETDEWEB)

    Varó, I., E-mail: inma@iats.csic.es [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Redón, S. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Garcia-Roger, E.M. [Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Burjassot (Spain); Amat, F.; Guinot, D. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain); Serrano, R. [Research Institute for Pesticides and Water (IUPA), Avda. Sos Baynat, s/n. University Jaume I, Castellón 12071 (Spain); Navarro, J.C. [Instituto de Acuicultura Torre de la Sal (IATS-CSIC), Ribera de Cabanes, Castellón 12595 Spain (Spain)

    2015-04-15

    Highlights: • Artemia species display an elevated tolerance to high ranges of chlorpyrifos. • A. franciscana survived better and its fecundity was less affected by chlorpyrifos. • The higher fecundity of A. franciscana is a selective advantage in colonization processes. • Higher survival and biological fitness in A. franciscana indicate out-competitive advantages. - Abstract: The genus Artemia consists of several bisexual and parthenogenetic sibling species. One of them, A. franciscana, originally restricted to the New World, becomes invasive when introduced into ecosystems out of its natural range of distribution. Invasiveness is anthropically favored by the use of cryptobiotic eggs in the aquaculture and pet trade. The mechanisms of out-competition of the autochthonous Artemia by the invader are still poorly understood. Ecological fitness may play a pivotal role, but other underlying biotic and abiotic factors may contribute. Since the presence of toxicants in hypersaline aquatic ecosystems has been documented, our aim here is to study the potential role of an organophosphate pesticide, chlorpyrifos, in a congeneric mechanism of competition between the bisexual A. franciscana (AF), and one of the Old World parthenogenetic siblings, A. parthenogenetica (PD). For this purpose we carried out life table experiments with both species, under different concentrations of the toxicant (0.1, 1 and 5 μg/l), and analyzed the cholinesterase inhibition at different developmental stages. The results evidence that both, AF and PD, showed an elevated tolerance to high ranges of chlorpyrifos, but AF survived better and its fecundity was less affected by the exposure to the pesticide than that of PD. The higher fecundity of AF is a selective advantage in colonization processes leading to its establishment as NIS. Besides, under the potential selective pressure of abiotic factors, such as the presence of toxicants, its higher resistance in terms of survival and biological

  1. Chronic Voluntary Ethanol Consumption Induces Favorable Ceramide Profiles in Selectively Bred Alcohol-Preferring (P Rats.

    Directory of Open Access Journals (Sweden)

    Jessica Godfrey

    achieved by alcohol-preferring P rats as a result of chronic voluntary exposure may have favorable vs. detrimental effects on lipid profiles in this genetic line, consistent with data supporting beneficial cardioprotective and neuroprotective effects of moderate ethanol consumption.

  2. Professional development programs in health promotion: tools and processes to favor new practices.

    Science.gov (United States)

    Torres, Sara; Richard, Lucie; Guichard, Anne; Chiocchio, François; Litvak, Eric; Beaudet, Nicole

    2017-06-01

    Developing innovative interventions that are in sync with a health promotion paradigm often represents a challenge for professionals working in local public health organizations. Thus, it is critical to have both professional development programs that favor new practices and tools to examine these practices. In this case study, we analyze the health promotion approach used in a pilot intervention addressing children's vulnerability that was developed and carried out by participants enrolled in a public health professional development program. More specifically, we use a modified version of Guichard and Ridde's (Une grille d'analyse des actions pour lutter contre les inégalités sociales de santé. In Potvin, L., Moquet, M.-J. and Jones, C. M. (eds), Réduire les Inégalités Sociales en Santé. INPES, Saint-Denis Cedex, pp. 297-312, 2010) analytical grid to assess deductively the program participants' use of health promotion practices in the analysis and planning, implementation, evaluation, sustainability and empowerment phases of the pilot intervention. We also seek evidence of practices involving (empowerment, participation, equity, holism, an ecological approach, intersectorality and sustainability) in the intervention. The results are mixed: our findings reveal evidence of the application of several dimensions of health promotion (equity, holism, an ecological approach, intersectorality and sustainability), but also a lack of integration of two key dimensions; that is, empowerment and participation, during various phases of the pilot intervention. These results show that the professional development program is associated with the adoption of a pilot intervention integrating multiple but not all dimensions of health promotion. We make recommendations to facilitate a more complete integration. This research also shows that the Guichard and Ridde grid proves to be a thorough instrument to document the practices of participants. © The Author 2015. Published by

  3. Contextualized Contribution of Kindness to Favorable Goal- and Circumstantial-Driven Neuropsychological Regulation

    Directory of Open Access Journals (Sweden)

    Nayara Mota

    2017-09-01

    Full Text Available Kindness involves care and non-judgmental understanding toward someone. As a prosocial inclination, kindness would increase the possibility of favorable interaction with the environment, with a successful adjustment of one's response in novel or challenging circumstances, taking into account rules or goals. This adjustment ability is commonly referred to as executive functions, dependent on the prefrontal and parietal functioning, still under development during late adolescence. This study aimed to investigate if kindness would relate with the executive functions. If so, it would correlate more with measures of self-regulation, mainly dependent on the medial prefrontal corticosubcortical circuits. Also, among self-regulating processes, kindness would be more associated with autonomic responses—choices guided by one's understanding/intention - than with adaptive responses—changes on one's choices triggered by unfavorable circumstances. A sample of 46 (31 female; 18 to 21 years-old healthy college students from the University of the State of Rio de Janeiro attended a clinical interview and a comprehensive neuropsychological assessment. Kindness was measured by the Compassion Scale subscore. Generalized non-linear models for each neuropsychological variable were executed on R, followed by an estimation of weighted parameters for each factor. Significant models which included kindness (weighted parameter Pc > 74 and all of their psychosocial or sociodemographic factors on their maximum expression (Pc > 74 were identified. In a contextualized joint influence with other psychosocial and sociodemographic factors, kindness fits equally goal- and circumstantial- self-regulation, as well as integrative organization of information. Kindness is a principle that optimizes a refreshing and prosocial interaction with the environment. As it anticipates sharing and cooperation behaviors, it might have a primordial function on individual and social

  4. Favorable Vascular Actions of Angiotensin-(1-7) in Human Obesity.

    Science.gov (United States)

    Schinzari, Francesca; Tesauro, Manfredi; Veneziani, Augusto; Mores, Nadia; Di Daniele, Nicola; Cardillo, Carmine

    2018-01-01

    Obese patients have vascular dysfunction related to impaired insulin-stimulated vasodilation and increased endothelin-1-mediated vasoconstriction. In contrast to the harmful vascular actions of angiotensin (Ang) II, the angiotensin-converting enzyme 2 product Ang-(1-7) has shown to exert cardiovascular and metabolic benefits in experimental models through stimulation of the Mas receptor. We, therefore, examined the effects of exogenous Ang-(1-7) on vasodilator tone and endothelin-1-dependent vasoconstriction in obese patients. Intra-arterial infusion of Ang-(1-7) (10 nmol/min) resulted in significant increase in unstimulated forearm flow ( P =0.03), an effect that was not affected by the Mas receptor antagonist A779 (10 nmol/min; P >0.05). In the absence of hyperinsulinemia, however, forearm flow responses to graded doses of acetylcholine and sodium nitroprusside were not different during Ang-(1-7) administration compared with saline (both P >0.05). During infusion of regular insulin (0.15 mU/kg per minute), by contrast, endothelium-dependent vasodilator response to acetylcholine was significantly enhanced by Ang-(1-7) ( P =0.04 versus saline), whereas endothelium-independent response to sodium nitroprusside was not modified ( P =0.91). Finally, Ang-(1-7) decreased the vasodilator response to endothelin A receptor blockade (BQ-123; 10 nmol/min) compared with saline (6±1% versus 93±17%; P obese patients Ang-(1-7) has favorable effects not only to improve insulin-stimulated endothelium-dependent vasodilation but also to blunt endothelin-1-dependent vasoconstrictor tone. These findings provide support for targeting Ang-(1-7) to counteract the hemodynamic abnormalities of human obesity. © 2017 American Heart Association, Inc.

  5. Consenting options for posthumous organ donation: presumed consent and incentives are not favored

    Directory of Open Access Journals (Sweden)

    Hammami Muhammad M

    2012-11-01

    Full Text Available Abstract Background Posthumous organ procurement is hindered by the consenting process. Several consenting systems have been proposed. There is limited information on public relative attitudes towards various consenting systems, especially in Middle Eastern/Islamic countries. Methods We surveyed 698 Saudi Adults attending outpatient clinics at a tertiary care hospital. Preference and perception of norm regarding consenting options for posthumous organ donation were explored. Participants ranked (1, most agreeable the following, randomly-presented, options from 1 to 11: no-organ-donation, presumed consent, informed consent by donor-only, informed consent by donor-or-surrogate, and mandatory choice; the last three options ± medical or financial incentive. Results Mean(SD age was 32(9 year, 27% were males, 50% were patients’ companions, 60% had ≥ college education, and 20% and 32%, respectively, knew an organ donor or recipient. Mandated choice was among the top three choices for preference of 54% of respondents, with an overall median[25%,75%] ranking score of 3[2,6], and was preferred over donor-or-surrogate informed consent (4[2,7], p vs. 11[6,11], respectively, p = 0.002. Compared to females, males more perceived donor-or-surrogate informed consent as the norm (3[1,6] vs. 5[3,7], p vs. 8[4,9], p vs. 5[2,7], p  Conclusions We conclude that: 1 most respondents were in favor of posthumous organ donation, 2 mandated choice system was the most preferred and presumed consent system was the least preferred, 3 there was no difference between preference and perception of norm in consenting systems ranking, and 4 financial (especially in females and medical (especially in males incentives reduced preference.

  6. Favorable circulatory system outcomes as adjuvant traditional Chinese medicine (TCM treatment for cerebrovascular diseases in Taiwan.

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    Hsienhsueh Elley Chiu

    Full Text Available This study searches the National Health Insurance Research Database (NHIRD used in a previous project, aiming for reconstructing possible cerebrovascular disease-related groups (DRG,and estimating the costs between cerebrovascular disease and related diseases.We conducted a nationwide retrospective cohort study in stroke inpatients, we examined the overall costs in 3 municipalities in Taiwan, by evaluating the possible costs of the expecting diagnosis related group (DRG by using the international classification of diseases version-9 (ICD-9 system, and the overall analysis of the re-admission population that received traditional Chinese medicine (TCM treatment and those who did not.The trend demonstrated that the non-participant costs were consistent with the ICD-9 categories (430 to 437 because similarities existed between years 2006 to 2007. Among the TCM patients, a wide variation and additional costs were found compared to non-TCM patients during these 2 years. The average re-admission duration was significantly shorter for TCM patients, especially those initially diagnosed with ICD 434 during the first admission. In addition, TCM patients demonstrated more severe general symptoms, which incurred high conventional treatment costs, and could result in re-admission for numerous reasons. However, in Disease 7 of ICD-9 category, representing the circulatory system was most prevalent in non-TCM inpatients, which was the leading cause of re-admission.We concluded that favorable circulatory system outcomes were in adjuvant TCM treatment inpatients, there were less re-admission for circulatory system events and a two-third reduction of re-admission within ICD-9 code 430 to 437, compared to non-TCM ones. However, there were shorter re-admission duration other than circulatory system events by means of unfavorable baseline condition.

  7. Geology and uranium favorability of the Sonora Pass region, Alpine and Tuolumne Counties, California

    Energy Technology Data Exchange (ETDEWEB)

    Rapp, J.S.; Short, W.O.

    1981-06-01

    Uranium mineralization at the Juniper Mine is restricted to host rocks of the Relief Peak Formation and is most common in coarse-grained lithic sandstone, conglomerate, and lithic wacke. The richest beds contain as much as 0.5% U/sub 3/O/sub 8/. Uranium is present as coffinite, uraninite, and unidentified minerals. Thorium/uranium ratios are generally low and erratic. Equivalent uranium determinations are low in comparison with chemical uranium values, indicating that uranium mineralization of the Juniper Mine is geologically young. Core drilling at 16 localities shows that widely separated exposures of the Relief Peak Formation have very similar lithology, geochemistry, and stratigraphy. Some sections are similar to the Juniper Mine section. Core from the bottom of drill hole SP-1 contains 83 ppM uranium, the greatest known concentration outside the mine area. Significant uranium deposits may be concealed beneath the thick Tertiary volcanic cover of the region. The quartz latitic Eureka Valley Tuff is fairly widespread in east-central California and western Nevada. It contains 12 to 14 ppM uranium and stratigraphically overlies the Relief Peak Formation. It is permeable and contains abundant alkali metals and volcanic glass. Because of its petrology, geochemistry, and position, this formation is the most likely source for uranium mineralization of the Sonora Pass region. It should be examined as a potential source rock in other areas with special regard to its relationship to carbonaceous sedimentary formations. The uraniferous granite pegmatitite dike that crops out in the Niagara Creek area appears too small to be a significant source rock. The most favorable rocks in the Sonora Pass region occur near the Juniper Mine and west of it, in the Dardanelles, the Whittakers Dardanelles, and the area of the Big Meadow Quadrangle. Potential uranium host rocks crop out in areas along the crest of the Sierra Nevada from Lake Tahoe to Yosemite.

  8. Geology and uranium favorability of the Sonora Pass region, Alpine and Tuolumne Counties, California

    International Nuclear Information System (INIS)

    Rapp, J.S.; Short, W.O.

    1981-06-01

    Uranium mineralization at the Juniper Mine is restricted to host rocks of the Relief Peak Formation and is most common in coarse-grained lithic sandstone, conglomerate, and lithic wacke. The richest beds contain as much as 0.5% U 3 O 8 . Uranium is present as coffinite, uraninite, and unidentified minerals. Thorium/uranium ratios are generally low and erratic. Equivalent uranium determinations are low in comparison with chemical uranium values, indicating that uranium mineralization of the Juniper Mine is geologically young. Core drilling at 16 localities shows that widely separated exposures of the Relief Peak Formation have very similar lithology, geochemistry, and stratigraphy. Some sections are similar to the Juniper Mine section. Core from the bottom of drill hole SP-1 contains 83 ppM uranium, the greatest known concentration outside the mine area. Significant uranium deposits may be concealed beneath the thick Tertiary volcanic cover of the region. The quartz latitic Eureka Valley Tuff is fairly widespread in east-central California and western Nevada. It contains 12 to 14 ppM uranium and stratigraphically overlies the Relief Peak Formation. It is permeable and contains abundant alkali metals and volcanic glass. Because of its petrology, geochemistry, and position, this formation is the most likely source for uranium mineralization of the Sonora Pass region. It should be examined as a potential source rock in other areas with special regard to its relationship to carbonaceous sedimentary formations. The uraniferous granite pegmatitite dike that crops out in the Niagara Creek area appears too small to be a significant source rock. The most favorable rocks in the Sonora Pass region occur near the Juniper Mine and west of it, in the Dardanelles, the Whittakers Dardanelles, and the area of the Big Meadow Quadrangle. Potential uranium host rocks crop out in areas along the crest of the Sierra Nevada from Lake Tahoe to Yosemite

  9. La alimentación de la gestante adolescente: el cambio favorable

    Directory of Open Access Journals (Sweden)

    ISABEL RODRÍGUEZ HERNÁNDEZ

    2010-06-01

    Full Text Available El presente estudio de tipo cualitativo y etnográfico de pequeño alcance, tiene como objetivo describir el significado del cuidado de sí de un grupo de gestantes adolescentes y su hijo por nacer, con relación a la alimentación, a partir de sus prácticas, creencias y valores culturales, quienes asistieron a control prenatal a la Unidad de Atención Primaria (UPA de Candelaria la Nueva, Hospital Vista Hermosa, Ciudad Bolívar, Localidad 19 de Bogotá, en 2007. La información fue aportada por ocho adolescentes primigestantes de entre 17 y 19 años de edad, que estaban entre el cuarto y séptimo meses de gestación, sin patologías asociadas, que asistieron al primer control prenatal, seleccionadas intencionalmente y que estuvieron dispuestas a participar de la investigación (previo consentimiento informado. La recolección de datos se realizó a través de la entrevista etnográfica no estructurada; se obtuvo como resultado el significado del cuidado en las gestantes adolescentes y se aportaron tres grandes beneficios positivos del cuidado de la alimentación materna: cambio de hábito alimentario, alimentarse para proteger la salud del bebé y para que nazca sano, y alimentarse para proteger la salud de la madre adolescente. Dichos resultados, conjugados en el escenario cultural de las gestantes adolescentes, permiten explorar y conocer cómo se cuidan ellas a través de las prácticas soportadas en el saber como conocimiento y razón, y el uso como los artefactos que utiliza.

  10. Avaliação da satisfação de pacientes oncológicos com atendimento recebido durante o tratamento antineoplásico ambulatorial Evaluación de la satisfaccíon de pacientes oncológicos con la atención recibida durante el tratamiento antineoplásico ambulatorial Evaluation of the satisfaction level of cancer patients with the assistance recieved during ambulatory antineoplastic chemoteraphy

    Directory of Open Access Journals (Sweden)

    Selma Montosa da Fonseca

    2006-10-01

    Full Text Available Este estudo descritivo, fundamentado na abordagem de resultados proposta por Donabedian, teve como objetivo avaliar o nível de satisfação de pacientes oncológicos com o atendimento recebido no Ambulatório de Quimioterapia de Adultos do Hospital São Paulo. A amostra incluiu 105 pacientes que aceitaram participar do estudo. A avaliação dos usuários foi positiva, tanto com o atendimento de enfermagem (54% muito bom e 46% bom, quanto com o atendimento global do serviço (50% muito satisfeitos e 46% satisfeitos. O nível de satisfação manifestado pelos usuários relacionou-se, principalmente, com a acessibilidade organizacional, o ambiente acolhedor e o processo assistencial nas dimensões da interação profissional/cliente e do desempenho técnico. No entanto, apontaram como medidas necessárias, evitar a falta de drogas e aumentar o número de vagas.Este estudio descriptivo, fundado en el abordaje de resultados propuesto por Donabedian, tuvo como objetivo evaluar el nivel de satisfacción de pacientes con cáncer con la atención recibida en el Ambulatorio de Quimioterapia de Adultos de Hospital São Paulo. La muestra incluyó 105 pacientes que aceptaron participar de la investigación. La evaluación de los usuarios fue positiva, tanto con la atención de enfermería (54% muy buena y 46% buena, cuanto con la atención general del servicio (50% muy satisfechos y 46% satisfechos.El nivel de satisfacción manifestado por los usuarios se relacionó, principalmente, con la accesibilidad organizacional, el ambiente acogedor y el proceso asistencial en las dimensiones de la interacción profesional/cliente y del desempeño técnico. No obstante, apuntaron como medidas necesarias, evitar la falta de medicinas y aumentar el número de plazas.This descriptive study, grounded upon Donabedian's outcomes approach, had as purpose to evaluate the satisfaction level of cancer patients with the assistance received at the Adult Chemotherapy Ambulatory

  11. Nutritional support in patients with severe acute pancreatitis Soporte nutricional en pacientes con pancreatitis aguda grave

    Directory of Open Access Journals (Sweden)

    Mónica Marcela Peláez Hernández

    2007-04-01

    Full Text Available Severe acute pancreatitis is associated with a systemic inflammatory response leading to a hypermetabolic, hypercatabolic condition; for those reasons, patients suffering from this disease require an excellent artificial nutritional support in order to maintain the structural integrity and the function of vital organs with minimal pancreatic secretion. Total parenteral nutrition has been the standard practice in the treatment of patients with severe acute pancreatitis because of the favorable outcomes of early nutritional support while avoiding pancreatic stimulation; however, recent evidence suggests there are potentially greater benefits with enteral as compared with parenteral nutrition, including fewer septic and metabolic complications and lesser costs. That is why present guidelines for the management of acute pancreatitis recommend that enteral instead of parenteral nutrition be used in patients with severe acute pancreatitis. La pancreatitis aguda, especialmente en su forma grave, está asociada con una respuesta inflamatoria sistémica que lleva a un estado de hipermetabolismo e hipercatabolismo, en el que se requiere un excelente soporte nutricional que permita mantener la integridad estructural y la función de los órganos vitales con un estímulo mínimo de la secreción pancreática. La nutrición parenteral total era el soporte de elección, que permitía obtener todos los beneficios de la nutrición temprana sin estimular la secreción pancreática; pero la evidencia actual muestra mayores beneficios con la nutrición enteral, porque se asocia con menos complicaciones infecciosas y metabólicas y con disminución en los costos. Por ello las guías actuales de tratamiento de la pancreatitis aguda grave recomiendan como primera elección el soporte nutricional enteral.

  12. IoT con Raspberry Pi

    OpenAIRE

    García Muelas, Carlos

    2015-01-01

    Estudio de diferentes plataformas software y hardware del internet de las cosas. Aplicación real con Raspberry Pi. Estudi de diferents plataformes programari i maquinari de l'internet de les coses. Aplicació real amb Raspberry Pi. Bachelor thesis for the Telecommunication Technologies program on Telematics.

  13. en personas con el VIH/SIDA

    Directory of Open Access Journals (Sweden)

    Ximena Palacios Espinosa

    2006-01-01

    Full Text Available El objetivo de este estudio fue hallar la relación de la intención e ideación suicida con algunas variables sociodemográficas, las características de la enfermedad, el tratamiento antirretroviral y los aspectos piscoafectivos en personas con el VIH/SIDA que residen en Bogotá (Colombia y pertenecientes a una fundación. Para ello, se tomó una muestra de 75 pacientes con VIH positivo a quienes se evaluó a través de una entrevista semiestructurada y dos instrumentos: el inventario de depresión de Beck (IBD y la escala de Ideación Suicida (SSI. Los resultados mostraron que solo 29 personas tenían ideación suicida y 10 intención suicida: De los 10 solo 2 sujetos tenían intención después del diagnóstico. Se encontró una relación estadística significativa para ideación suicida e intención suicida con edad, estrato socioeconómico, estado civil, orientación sexual, las características de la enfermedad, el tratamiento antirretroviral y los aspectos piscoafectivos.

  14. La relazione empatica con i robot

    NARCIS (Netherlands)

    Marti, P.; Iacono, I.; Tittarelli, M.

    2013-01-01

    È possibile instaurare una relazione empatica tra un essere umano e un robot? Il presente studio valuta le soluzioni di design adottate nella progettazione di una maschera empatica, implementata su un tablet, che consente all’anziano di dialogare nell’ambiente domestico con un robot che lo assiste

  15. Las construcciones con esqueleto en madera

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    Heinz Leser S.

    1984-06-01

    Estos sistemas se emplean preferentemente en viviendas prefabricadas y edificios de pequeña envergadura. Finalmente, consideramos las construcciones con "esqueleto en madera", cuyo campo de aplicación principal está en las edificaciones de mediana extensión: escuelas, centros comunitarios, pequeñas industrias o bloques habitacionales.

  16. Conversazioni autobiografiche con Albino Sacco-Casamassima

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    Orazio Maria Valastro

    2004-03-01

    Full Text Available Nel 1948 venne Olivetti a Matera. Olivetti venne a Matera con un certo ambasciatore americano che praticamente aveva preparato o stava dando una mano per il piano Marschall, venne a Matera e mi vollero incontrare. Io sono stato chiamato dalla piazza, stavo nella piazza, era il mese di luglio, una cosa di questo genere, e andai in un bar, un bar ad angolo mi ricordo in Via Don Minzioni, dove questo Olivetti mi disse 'ma lei che cosa fa coi sassi?' 'Che cos'è questa storia?' Gli raccontai un po' che cosa facevo io con questi amici, avevamo fatto questo, insomma tutto quello che avevamo fatto nei sassi e che volevamo preparare ancora per presentare a qualcuno un piano di revisionamento dei sassi. Mi ricordo, era la prima volta che avevo visto Adriano Olivetti, ne avevo sentito parlare però non avevo mai visto quest'uomo con gli occhi celesti, minuto, coi capelli bianchi, riccioluto, con una cravatta bianca, cosa che mi fece impressione, una specie di angelo.

  17. Procesamiento de argumentos en personas con afasia

    Directory of Open Access Journals (Sweden)

    Luis Martínez

    2012-06-01

    Full Text Available En las personas con afasia se alteran diversos procesos lingüísticos. Entre las alteraciones más comunes tenemos aquellas que se producen en el procesamiento sintáctico, lo cual es evidente en el procesamiento de los argumentos. Investigaciones previas realizadas a sujetos con afasia reflejan un procesamientodeficiente de argumentos, lo cual se hace más evidente a medida que el número de argumentos aumenta. Se ha encontrado que mientras mayor es la complejidad en la estructura de la oración, los sujetos afásicos manifiestan mayores dificultades en el procesamiento de la misma. El presente estudio indaga en las dificultades que presentan los sujetos adultos con trastornos afásicos hablantes de español en el procesamiento de argumentos durante tareas de descripción. Este trabajo corrobora la evidencia de que los sujetos con afasia manifiestan un manejo deficiente en el procesamiento de argumentos en las tareas señaladas.

  18. Coriocarcinoma con metástasis pulmonar

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    Vicia Sánchez Abalos

    2014-05-01

    Full Text Available Se presenta el caso clínico de una fémina de 44 años de edad, con 32 semanas de embarazo, la cual fuera ingresada en la Unidad de Cuidados Intensivos del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba, por presentar insuficiencia respiratoria aguda como consecuencia de una sepsis. La paciente fue tratada con cefalosporina de tercera generación y ventilación mecánica no invasiva, pero se mantuvieron las características gasométricas de hipoxemia y una mala reacción terapéutica, por lo que se requirió instrumentación de las vías respiratorias y soporte hemodinámico, sin lograr regresión del cuadro clínico, lo cual condujo a un paro cardiorrespiratorio y, con ello, a la muerte. La necropsia mostró un coriocarcinoma del endometrio con metástasis pulmonar

  19. Con la testa fra le nuvole

    Directory of Open Access Journals (Sweden)

    André Greboge

    2015-06-01

    Full Text Available Partitura de Con la testa fra le nuvole, composta em 2015 para piano e harpa de pedais. Este memorial apresenta as notas sobre a obra e a organização do processo composicional, baseada em um insight composicional a partir da ideia de complexidade apresentada por James Tenney em Meta Meta-hodos (1988.

  20. REDUCCIÓN DE ÓXIDOSDE NITROGENO CON CATALIZADORES ZEOLÍTICOS INTERCAMBIADOS CON COBALTO

    Directory of Open Access Journals (Sweden)

    Enrique Alexis García Moya

    2012-10-01

    Full Text Available Se presenta un estudio sobre la reducción catalítica selectiva (RCS de NOx con metano en presencia de oxígeno en exceso con varios catalizadores a base de las zeolitas mordenita, ferrierita y ZSM-5 intercambiadas con diferentes cargas de cobalto y con las correspondientes zeolitas en forma acida. Cuando la mezcla reactiva contenía mayormente NO2 en lugar de NO, los catalizadores ácidos mostraron las más altas velocidades de formación de N2 en condiciones secas. Las mayores actividades se obtuvieron con los catalizadores Co-mordenita, siguiendo en orden de actividad los catalizadores Co-Ferrierita y Co-ZSM-5. El catalizador Co-Mordenita más activo se ensayó con una mezcla reactiva donde predominó el NO en lugar del NO2 bajo condiciones secas e hidrotérmicas y en presencia de SO2. Con la adición de 8% de agua a la mezcla de reacción se observó desactivación reversible, especialmente a bajas temperaturas. La adición de 60 ppm de SO2 disminuyó la velocidad de reacción aproximadamente a la mitad debido posiblemente al envenenamiento de algunos sitios activos.

  1. Ugandan Women's View of the IUD: Generally Favorable but Many Have Misperceptions About Health Risks.

    Science.gov (United States)

    Twesigye, Rogers; Buyungo, Peter; Kaula, Henry; Buwembo, Dennis

    2016-08-11

    Between 2001 and 2006, IUD use in Uganda stagnated at 0.2% among women of reproductive age (WRA) ages 15-49. By 2011, IUD use had increased slightly to 0.4%. Recent studies report a significant increase in IUD use to 3.8%, but it is still low. Because the IUD is a little-used method in Uganda, we assessed the acceptability of the IUD by surveying women about their perceptions, attitudes, and beliefs. In August and September 2014, we conducted a cross-sectional survey among 1,505 WRA exiting public and private health facilities in Uganda. We collected information on women's attitudes, knowledge, and beliefs about the IUD, as well as their perceptions about its availability. We classified women's responses according to a behavior change framework with 3 summary constructs: opportunity (structural factors that influence behavior), ability (skills to perform the behavior), and motivation (self-interest in adopting the behavior). As these 3 types of factors are more favorable to the desired behavior (in this case, use of the IUD), individuals are more likely to perform the behavior. Cross-tabulations compared the percentage results of perceptions and knowledge by key background characteristics. Most (87.8%) of the surveyed women had heard of the IUD, and nearly two-thirds had a positive attitude toward the method. But a lower percentage (38.6%) had accurate information about the IUD and more than half (51.6%) did not think the method was available in a nearby facility. More than half of the women believed incorrectly that the IUD can damage the womb (57%), that it reduces sexual pleasure (54%), and that it can cause cancer (58%). Current use of family planning or of a modern method specifically was positively associated with awareness and accurate knowledge and beliefs about the IUD. Married women had significantly higher awareness of the IUD than single women, and they had better knowledge and belief scores. The type of facility used for health care services (public

  2. Favored subjects and psychosocial needs in music therapy in terminally ill cancer patients: a content analysis.

    Science.gov (United States)

    Preissler, Pia; Kordovan, Sarah; Ullrich, Anneke; Bokemeyer, Carsten; Oechsle, Karin

    2016-05-12

    Research has shown positive effects of music therapy on the physical and mental well-being of terminally ill patients. This study aimed to identify favored subjects and psychosocial needs of terminally ill cancer patients during music therapy and associated factors. Forty-one Patients receiving specialized inpatient palliative care prospectively performed a music therapy intervention consisting of at least two sessions (total number of sessions: 166; per patient average: 4, range, 2-10). Applied music therapy methods and content were not pre-determined. Therapeutic subjects and psychosocial needs addressed in music therapy sessions were identified from prospective semi-structured "field notes" using qualitative content analysis. Patient- and treatment-related characteristics as well as factors related to music and music therapy were assessed by questionnaire or retrieved from medical records. Seven main categories of subjects were identified: "condition, treatment, further care", "coping with palliative situation", "emotions and feelings", "music and music therapy", "biography", "social environment", and "death, dying, and spiritual topics". Patients addressed an average of 4.7 different subjects (range, 1-7). Some subjects were associated with gender (p = .022) and prior impact of music in patients' life (p = .012). The number of subjects per session was lower when receptive music therapy methods were used (p = .040). Psychosocial needs were categorized into nine main dimensions: "relaxing and finding comfort", "communication and dialogue", "coping and activation of internal resources", "activity and vitality", "finding expression", "sense of self and reflection", "finding emotional response", "defocusing and diversion", and "structure and hold". Patients expressed an average of 4.9 psychosocial needs (range, 1-8). Needs were associated with age, parallel art therapy (p = .010), role of music in patient's life (p = .021), and the applied music

  3. Lower-energy radiofrequency thermotherapy for benign prostatic hyperplasia. Prediction of a favorable treatment outcome

    International Nuclear Information System (INIS)

    Yanagisawa, Ryozo

    2007-01-01

    We evaluated short- and long-term results of lower-energy radiofrequency transurethral thermotherapy (TURT) for the treatment of benign prostatic hyperplasia and we investigated the predictors for a favorable treatment outcome. A total of 106 patients with benign prostatic hyperplasia underwent TURT, with TP10 used on 65 patients and Thermex I used on 41 patients. The assessment protocol consisted of international prostate symptom score (IPSS), quality of life (QOL) index, urodynamic study, dates of additional treatments and prostate examinations using transrectal ultrasonography and magnetic resonance imaging (MRI). Kaplan Meier survival analyses and logrank tests were used to assess an additional treatment-free period. At 3 months, the mean IPSS and QOL index had significantly decreased from 14.9 to 8.5 and from 4.2 to 2.5, respectively. Mean maximum flow rate had slightly but significantly increased from 11.4 to 11.9 ml per second. In accordance with guidelines proposed by the Japanese Urological Association, the overall clinical efficacy rate was 26.4%, including excellent, 7.5% and good, 18.9%. The efficacy rate was maintained for up to three years (29%) after the treatments in 31 patients who were able to be completely reevaluated. High IPSS and QOL index score were the predictors for short-term treatment outcome. Of the 106 patients, 76 were assessed by MRI before and 10 to 14 days after the treatment. The ranges of post-treatment-increased T2 signal were inversely associated with prostate volume. Kaplan Meier analysis indicated that 55% of the patients remained on TURT monotherapy five years after the treatment. Additional treatment-free periods were significantly longer in patients with an IPSS of 15 or less, with a QOL index of 4 or less, with a maximum flow rate of 10 ml per second or more, with a transition zone ratio of less than 0.4, or with a Schaefer obstruction grade of II or less at baseline. In conclusion, lower-energy radiofrequency

  4. A combination of extreme environmental conditions favor the prevalence of Endospore-forming Firmicutes

    Directory of Open Access Journals (Sweden)

    Sevasti Filippidou

    2016-11-01

    for which active growth could be expected, and phylotypes that are most likely in the state of endospores, in all the sites. In summary, our results suggest that diversified survival strategies, including sporulation and metabolic adaptations, explain the biological success of EFF in geothermal and natural springs, and that multiple extreme environmental factors favor the prevalence of EFF.

  5. FADS1 rs174549 Polymorphism May Predict a Favorable Response to Chemoradiotherapy in Oral Cancer Patients.

    Science.gov (United States)

    Chen, Fa; He, Baochang; Yan, Lingjun; Qiu, Yu; Lin, Lisong; Cai, Lin

    2017-01-01

    The fatty acid desaturase 1 (FADS1) gene variant is a novel susceptibility marker for laryngeal squamous cell carcinoma identified by a recent genome-wide association study, but it is still unclear whether this genetic variant continues to influence oral cancer recurrence or death. The purpose of this study was to evaluate the role of FADS1 rs174549 polymorphism and its interaction with postoperative chemoradiotherapy in the prognosis of oral cancer. A prospective cohort study involving 304 oral cancer patients with surgical resection was conducted in Fujian, China. Demographic and clinical data (adjuvant therapy types, histologic types, clinical stage, etc.) were extracted from medical records, and follow-up data were obtained by telephone interviews. We collected 5 to 8 mL of venous blood from all patients for DNA extraction, and rs174549 genotypes were determined by TaqMan assays (Life Technologies, Carlsbad, CA). A Cox proportional hazards model and Kaplan-Meier curve were used to assess the association between FADS1 rs174549 polymorphism and progression-free survival (PFS), as well as overall survival, in oral cancer. Carrying the AA genotype was significantly associated with a decreased risk of PFS: The hazard ratio was 0.52 (95% confidence interval, 0.29 to 0.93) for the codominant model and 0.54 (95% confidence interval, 0.31 to 0.94) for the recessive model. Moreover, better PFS was particularly obvious in patients who had received chemoradiotherapy. A positive multiplicative interaction between FADS1 rs174549 polymorphism and chemoradiotherapy was observed for PFS (P = .036). No significant association was found between FADS1 rs174549 polymorphism and overall survival. Our study suggests, for the first time, that FADS1 rs174549 polymorphism is a potentially independent and favorable factor in predicting oral cancer PFS especially for patients who undergo chemoradiotherapy, and it may serve as a potential target for individualized treatment in the future

  6. Favorable neonatal outcomes among immigrants in Taiwan: evidence of healthy immigrant mother effect.

    Science.gov (United States)

    Hsieh, Wu-Shiun; Hsieh, Chia-Jung; Jeng, Suh-Fang; Liao, Hua-Fang; Su, Yi-Ning; Lin, Shio-Jean; Chang, Pei-Jen; Chen, Pau-Chung

    2011-07-01

    . Evidence of a healthy immigrant mother effect on neonatal health is clear. Despite lower parental education, advancing paternal age, and spatial distribution disparity, babies born to married immigrant mothers in Taiwan had favorable neonatal outcomes.

  7. Are Press Depictions of Affordable Care Act Beneficiaries Favorable to Policy Durability?

    Science.gov (United States)

    Chattopadhyay, Jacqueline

    2015-01-01

    status, age, gender, and race/ethnicity appear to receive little attention. Existing literature suggests that these portrayal patterns may both support and limit ACA durability. In favor of durability is that ACA beneficiaries are depicted in terms that have been associated with deservingness in past American social policy--particularly being cast as workers and insiders. Yet, the results also give three reasons for caution. First, ACA insurance-losers are also portrayed as deserving. Second, it is unclear how the portrayal patterns found may impact the durability of the ACA's efforts to cut insurance disparities by age, health status, and especially race/ethnicity. Third, portrayals' strong casting of beneficiaries as workers, and limited attention to beneficiaries' economic heterogeneity and to young adults, may do little to help cultivate beneficiary political engagement around the ACA.

  8. Are human embryos Kantian persons?: Kantian considerations in favor of embryonic stem cell research.

    Science.gov (United States)

    Manninen, Bertha Alvarez

    2008-01-31

    paper by drawing from Allen Wood's work in Kantian philosophy in order to generate an argument in favor of hESCR.

  9. Are human embryos Kantian persons?: Kantian considerations in favor of embryonic stem cell research

    Directory of Open Access Journals (Sweden)

    Manninen Bertha

    2008-01-01

    operation. Finally, I will end the paper by drawing from Allen Wood's work in Kantian philosophy in order to generate an argument in favor of hESCR.

  10. Manejo de conductos radiculares con curvatura marcada

    Directory of Open Access Journals (Sweden)

    Jorge Mario Nuñez Duran

    2013-10-01

    Full Text Available Las variaciones anatómicas en dientes con conductos que poseen dilaceraciones hacen del tratamiento de endodonciaun reto o una complicación relativa, en donde el clínico debe desarrollar toda su habilidad y el uso de instrumentosespeciales que faciliten u optimicen la terapia de conductos radiculares. La toma de radiografías previas con diferentesangulaciones y el estudio minucioso de ellas, darán una ayuda fundamental para conocer más detalladamente estacomplicación anatómica, que en algunos casos es muy frecuente. El uso de instrumental más flexible y resistentepermite llegar con mayor precisión y seguridad a la parte apical sin que se corra el riesgo de fracturar los instrumentos,limpiándolos y modelándolos en toda su extensión para poder obturarlos de una manera correcta.El uso de limas de menor calibre, precurvadas, permite acceder a la porción dilacerada de la raíz. Este es un métodoeficaz para prevenir la perdida de longitud de trabajo y evitar así las perforaciones de las raíces durante la preparación.Dentro de los errores más comunes durante la instrumentación de los conductos está la perdida de longitud detrabajo, junto con la transportación del foramen apical, ya sea de manera externa o interna. En el presente artículose menciona el uso de nuevas y mejores técnicas usadas para poder evitar este tipo de errores y se muestra un casoclínico del manejo de un molar superior con una curvatura de 40 grados que fue preparado y obturado exitosamentecon el sistema Protaper (Dentsply- maillefer.

  11. Evaluación del desenlace y características clínicas de una serie de niños con neutropenia febril sin foco en el Hospital Universitario San Vicente de Paúl, Medellín, Colombia, 2000-2005

    Directory of Open Access Journals (Sweden)

    María Adelaida Aristizábal Gil

    2008-11-01

    Full Text Available Introducción: la neutropenia febril (NF se asocia a infección en 48-60% de los casos y es la segunda causa de ingreso hospitalario al servicio de oncología pediátrica. El objetivo del estudio fue evaluar el desenlace de una serie de niños, que recibían tratamiento para neutropenia febril sin foco aparente, según un protocolo preestablecido en el Servicio de Hematooncología infantil del Hospital Universitario San Vicente de Paúl. MATERIALES Y MÉTODOS: se incluyeron retrospectivamente historias clínicas de pacientes menores de 15 años con diagnóstico nuevo de neoplasia maligna y neutropenia febril sin foco, hospitalizados en un lapso de 5 años. Los datos se registraron en un formato preestablecido. RESULTADOS: se incluyeron 103 historias clínicas con 182 episodios de NF; 34,1% fueron pacientes con leucemia linfoblástica riesgo estándar (LLA, 19,8% LLA de alto riesgo y 13,7%, linfoma no Hodking. 68,1% tuvieron NF grave y en 94,5% se había aplicado quimioterapia previa (79,7% intensiva. La infección se documentó clínicamente en 38,4% y microbiológicamente en 25,2% de los episodios; hubo bacteriemia en 15,4% de los episodios, 3,3% con urocultivo positivo y 6,5% con aislamiento del invasor en otros sitios. Los microorganismos más frecuentes fueron Escherichia coli (24% y Pseudomonas aeruginosa (13%. Hubo mayor resistencia a ceftriazona y cefatzidime tanto de gérmenes grampositivos como de gramnegativos y producción de betalactamasas en 9% durante un año de evaluación; 50% de los aislamientos de S. aureus coagulasa negativo fueron resistentes a oxacilina. En 37 episodios hubo complicaciones (20,2%, la más frecuente de las cuales fue la afectación cardiopulmonar; en 25,2% fracasó el tratamiento, en 21,4% hubo respuesta parcial y 7 pacientes (3,8% fallecieron. CONCLUSIONES: los hallazgos son similares a los reportados por otros autores; predominan en nuestra unidad los microorganismos gramnegativos como causa importante de

  12. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    OpenAIRE

    Viridiana Vanessa Conzuelo-González

    2009-01-01

    El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria) entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un estud...

  13. Terapias alternativas con animales para niños con necesidades especiales

    OpenAIRE

    Cea-Chueca, Aihnoa

    2014-01-01

    El presente trabajo de fin de grado consiste en la realización de un análisis y descripción de la literatura acerca de las distintas terapias animales, destinadas a niños con necesidades especiales: cómo y por qué surgieron, en qué consisten las terapias, cómo podemos utilizarlas, etc. Las terapias alternativas con animales se conocen como una alternativa terapéutica, donde se utiliza a un animal como co-terapeuta para poder desarrollar diferentes capacidades de los niños con necesidades espe...

  14. Variables socionutricionales de hogares mazahuas integrados por preescolares desnutridos con madres con obesidad y sin obesidad

    OpenAIRE

    Viridiana Vanessa Conzuelo-González; Ivonne Vizcarra-Bordi

    2009-01-01

    El primer objetivo fue conocer cuántos menores de cinco años con diferentes grados de desnutrición tienen una madre con sobrepeso/obesidad/ en una comunidad indígena que vive en extrema pobreza y bajo condiciones de migración masculina internacional. El segundo fue comparar tres variables socionutricionales (ingreso familiar, educación de la madre y adecuación nutrimental de la dieta diaria) entre estos hogares y los hogares con desnutrición infantil y madres sin obesidad. Se realizó un est...

  15. Tratamiento mediante dilatación con balón de un paciente con estenosis subaórtica por membrana: a propósito de un caso

    Directory of Open Access Journals (Sweden)

    Carlos Mariño

    2013-10-01

    Full Text Available La estenosis subaórtica es una lesión cardiaca poco frecuente, en el cual el tracto de salida del ventrículo izquierdo está estrechado por la presencia de un anillo fibroso o fibromuscular. Constituye 8 a 20% de todas las formas de obstrucción al tracto de salida del ventrículo izquierdo. La cirugía ha sido considerada el tratamiento de elección cuando el gradiente pico es mayor de 50 mmHg o en pacientes que, con gradientes menores, presentan progresión de la insuficiencia aórtica o dilatación de los diámetros ventriculares, disfunción ventricular o síntomas. Presentamos el caso de un paciente menor de edad, portador de estenosis subaórtica por membrana, con síntomas de insuficiencia cardiaca y función ventricular izquierda muy comprometida, en la que se realizó el tratamiento percutáneo, alternativo al quirúrgico, con resultado exitoso. Constituye el primer caso reportado en el país de tratamiento percutáneo con balón y con evolución favorable.

  16. Preliminary study of favorability for uranium of the Sangre de Cristo Formation in the Las Vegas basin, northeastern New Mexico

    International Nuclear Information System (INIS)

    May, R.T.; Strand, J.R.; Reid, B.E.; Phillips, W.R.

    1977-12-01

    Uranium favorability of the Sangre de Cristo Formation (Pennsylvanian-Permian) in the Las Vegas basin has been evaluated. The Las Vegas basin project area, located in Colfax, Mora, and San Miguel Counties, New Mexico, comprises about 3,489 sq mi. The formation contains sedimentologic and stratigraphic characteristics that are considered favorable for uranium deposition. Field investigations consisted of section measuring, rock sampling, and ground radiometric reconnaissance. North-south and east-west cross sections of the basin were prepared from well logs and measured sections. Petrographic, chemical, and spectrographic analyses were conducted on selected samples. Stratigraphic and sedimentologic information were used to determine depositional environments. The most favorable potential host rocks include red to pink, coarse-grained, poorly sorted, feldspathic to arkosic lenticular sandstones with stacked sandstone thicknesses of more than 20 ft and sandstone-to-shale ratios between 1:1 and 2:1. The sandstone is interbedded with mudstone and contains carbonaceous debris and anomalous concentrations of uranium locally. Areas of maximum favorability are found in a braided-stream, alluvial-plain depositional environment in the north-central part of the Las Vegas basin. There, carbonaceous material is well preserved, probably due to rapid subsidence and burial. Furthermore, uranium favorability is highest in the lower half of the formation because carbonaceous wood and plant fragments, as well as known uranium deposits, are concentrated in this zone. Piedmont deposits in the north and east, and meander-belt, alluvial-plain deposits in the south, are not considered favorable because of the paucity of uranium deposits and a minimum of carbonaceous material

  17. Criteria for uranium occurrences in Saskatchewan and Australia as guides to favorability for similar deposits in the United States

    International Nuclear Information System (INIS)

    Kalliokoski, J.; Langford, F.F.; Ojakangas, R.W.

    1978-07-01

    The objective of this study was to explain the occurrence of the large uranium deposits that have been found in northern Saskatchewan and the Northern Territory of Australia, to provide criteria to evaluate the favorability of Proterozoic rocks in the United States for similar deposits. All of these deposits belong to the class known as the Proterozoic unconformity-type pitchblende deposits. Chapters are devoted to: uranium deposits in Saskatchewan; uranium deposits of the Darwin and Arnhem Land area, Northern Territory of Australia; model for the Proterozoic unconformity-type pitchblende deposits; and evaluation of the geology of selected states for its favorability for Proterozoic unconformity-type pitchblende deposits

  18. Sustained favorable long-term outcome in the treatment of schizophrenia: a 3-year prospective observational study

    Directory of Open Access Journals (Sweden)

    Ascher-Svanum Haya

    2011-08-01

    Full Text Available Abstract Background This study of chronically ill patients with schizophrenia aimed to identify patients who achieve sustained favorable long-term outcome - when the outcome incorporates severity of symptoms, level of functioning, and use of acute care services - and to identify the best baseline predictors of achieving this sustained favorable long-term outcome. Methods Using data from the United States Schizophrenia Care and Assessment Program (US-SCAP (N = 2327, a large 3-year prospective, multisite, observational study of individuals treated for schizophrenia in the US, a hierarchical cluster analysis was performed to group patients based upon baseline symptom severity. Symptom severity was assessed using the Positive and Negative Syndrome Scale (PANSS scores, level of functioning, and use of acute care services. Level of functioning reflected patient-reported productivity and clinician-rated occupational role functioning. Use of acute care services reflected self-reported psychiatric hospitalization and emergency service use. Change of health state was determined over the 3-year period. A patient was classified as having a sustained favorable long-term outcome if their health state values had the closest distance to the defined "best baseline cluster" at each point over the length of the study. Stepwise logistic regression was used to determine baseline predictors of sustained favorable long-term outcome. Results At baseline, 5 distinct health state clusters were identified, ranging from "best" to "worst." Of 1635 patients with sufficient data, only 157 (10% experienced sustained favorable long-term outcome during the 2-years postbaseline. The baseline predictors associated with sustained favorable long-term outcome included better quality of life, more daily activities, patient-reported clearer thinking from medication, better global functioning, being employed, not being a victim of a crime, not having received individual therapy, and not

  19. LA FORMACION DE LOS DOCENTES EN LA INTERVENCION CON ALUMNOS/AS CON DEFICIT DE ATENCION CON HIPERACTIVIDAD (TDAH

    Directory of Open Access Journals (Sweden)

    Francisco D. Fernández Martín

    2004-06-01

    Full Text Available La presencia del Trastorno por d.ficit de atención con hiperactividad (TDAH en algunos/as de nuestros/as alumnos/as ocasiona serios problemas para que estos/as se adapten al contexto escolar y sociofamiliar en el que se desenvuelven, debido a la presencia de una serie de dificultades: hiperactividad, dificultades para mantener la atenci.n, autorregular la conducta, controlarse, etc.

  20. Câncer de mama e sofrimento psicológico: aspectos relacionados ao feminino El cáncer de mama y el sufrimiento psicológico: aspectos relacionados con el femenino Breast cancer and psychological suffering: female-related aspects

    Directory of Open Access Journals (Sweden)

    Lucia Cecilia da Silva

    2008-06-01

    Full Text Available No Brasil e no mundo a incidência do câncer de mama vem aumentando e aparecendo cada vez mais cedo na vida da mulher. O tratamento envolve mastectomia, quimioterapia e radioterapia, que, pelos seus efeitos físicos, podem comprometer em variados graus a auto-estima, a imagem corporal e a identidade feminina daquelas que recebem o diagnóstico da doença. Além disso, em nossa sociedade o câncer adquiriu significados relacionados a culpa, punição, deterioração, dor e morte, agravando o sofrimento psicológico das doentes. Neste sentido, este artigo tem o objetivo de levantar alguns pontos de reflexão no que se relaciona aos significados culturais da doença e do significado do seio enquanto ícone da identidade feminina. Partimos do princípio de que enriquecer a compreensão dos aspectos que influenciam o sofrimento da mulher com câncer de mama contribui para que os profissionais de saúde, principalmente os de saúde mental, possam assisti-la de maneira mais eficiente e abrangente.En Brasil y en el mundo la incidencia del cáncer de mama está en acenso. Es una enfermedad que está manifestándose cada vez más temprano en la vida de la mujer. El tratamiento envuelve mastectomía, quimioterapia y radioterapia que, por sus efectos físicos, pueden comprometer en variados grados la autoestima, la imagen corporal y la identidad femenina de aquellas mujeres que reciben el diagnóstico de la enfermedad. Además de eso, en nuestra sociedad el cáncer ha adquirido significados relacionados con la culpa, punición, deterioración, dolor y muerte, agravando el sufrimiento psicológico de las enfermas. En este sentido, este artículo tiene como objetivo levantar algunos puntos de reflexión en lo que se relaciona con los significados culturales de la enfermedad y del significado del seno como icono de la identidad femenina. Partimos del supuesto de que enriquecer la comprensión de los aspectos que pueden influenciar el sufrimiento de la mujer

  1. Esporotricosis cutánea diseminada con compromiso articular en una mujer con diabetes tipo 2

    Directory of Open Access Journals (Sweden)

    Sendy Solorzano

    Full Text Available La esporotricosis diseminada es una presentación infrecuente de esta micosis. Aunque ha sido descrita en sujetos inmunocompetentes, con frecuencia existe compromiso de la inmunidad mediada por células T. Reportamos el caso de una mujer con diabetes tipo 2 no controlada que desarrolló esporotricosis cutánea diseminada. El curso de la enfermedad presentó varias complicaciones que incluyeron hepatitis secundaria a itraconazol y artritis de la rodilla con cultivo positivo para Sporothrix schenckii durante el tratamiento con solución saturada de ioduro de potasio. La discusión del caso incluye aspectos de la patogénesis de la esporotricosis diseminada y el manejo de la infección y sus complicaciones.

  2. Favorable bed utilization and readmission rates for emergency department observation unit heart failure patients.

    Science.gov (United States)

    Schrager, Justin; Wheatley, Matthew; Georgiopoulou, Vasiliki; Osborne, Anwar; Kalogeropoulos, Andreas; Hung, Olivia; Butler, Javed; Ross, Michael

    2013-06-01

    ) among patients admitted from the OU (p time was not significantly different between the comparison groups at both 30 and 90 days of follow-up. Selected acute heart failure (HF) patients managed by a rapid treatment protocol in the OU demonstrated favorable hospital use, with discharged patients using fewer bed-days and demonstrating readmission rates that were not higher than admitted patients. © 2013 by the Society for Academic Emergency Medicine.

  3. Consenting options for posthumous organ donation: presumed consent and incentives are not favored

    Science.gov (United States)

    2012-01-01

    less preferred mandated choice with medical incentive option (7[4,9] vs. 5[2,7], p < 0.001). There was no association between consenting options ranking scores and age, health status, education level, or knowing an organ donor or recipient. Conclusions We conclude that: 1) most respondents were in favor of posthumous organ donation, 2) mandated choice system was the most preferred and presumed consent system was the least preferred, 3) there was no difference between preference and perception of norm in consenting systems ranking, and 4) financial (especially in females) and medical (especially in males) incentives reduced preference. PMID:23173834

  4. Riesgo familiar total en familias con mujeres diagnosticadas con neoplasia de mama

    Directory of Open Access Journals (Sweden)

    Nancy Cecilia Charrys-Bravo

    2017-07-01

    Full Text Available Objetivo: Determinar el riesgo familiar total de las familias con mujeres diagnosticadas con cáncer de mama, que asisten a un centro de salud oncológico en la ciudad de Barranquilla. Materiales y Métodos: El estudio fue de tipo descriptivo, transversal con abordaje cuantitativo. Se utilizó el instrumento Riesgo Familiar Total RFT 5-33. El universo estuvo conformado por familias con mujeres diagnosticadas con cáncer en mama. La muestra fue de 41 familias que integraron a 154 miembros; se abordó el estudio de manera censal, y no por medio de una muestra, porque el acceso a la información de la totalidad de las familia fue viable. Resultados: Los resultados mostraron que las familias, en su mayoría, son de tipo 2. El 68 % de las pacientes categorizan sus familias como amenazadas, el 5 % como familias de alto riesgo y un 27 % de las familias con un bajo riesgo. Conclusiones: Los hallazgos encontrados en esta investigación son importantes para las familias, lo cual permitirá establecer acciones y actividades que logren orientar e implementar procesos de atención específicos con el propósito de cuidar a las familias para que se mantengan sanos en un nivel de bajo riesgo; además, desarrollar controles y seguimiento a aquellas familias que se encuentran en un riesgo alto de amenazas, mediante acciones de promoción y prevención de la enfermedad de una manera amplia. Por lo anterior, se deben emprender programas más agresivos de prevención y promoción, especialmente con las familias que asisten en busca de apoyo médico para este padecimiento; de esta forma, se podrán diagnosticar los casos de forma temprana y proceder al respectivo tratamiento.

  5. Materiales nanocumpuestos basados en LDPE relleno con nanotubos de carbono con potenciales propiedades bactericidas

    OpenAIRE

    Benigno Escribano, Erika

    2015-01-01

    En este trabajo, se ha seleccionado como material de estudio polietileno de baja densidad, LDPE, ya que es un polímero con múltiples aplicaciones en diversos campos. Se busca como objetivo principal, preparar y caracterizar nuevos materiales basados en LDPE con potenciales propiedades antibacterianas. Para ello, se van a estudiar dos posibles maneras de conseguirlo: La primera de ellas, consiste en realizar un procesado mecánico sobre el polietileno, concretamente, una molienda del alta en...

  6. Estrategias vinculadas a la atención de los estudiantes universitarios con discapacidad

    Directory of Open Access Journals (Sweden)

    Elaineth Abasali

    2018-01-01

    Full Text Available El objetivo de este estudio fue desarrollar estrategias instruccionales vinculadas a la atención de estudiantes universitarios con discapacidad, pertenecientes a la UPEL-IPC. La metodología estuvo constituida por un proyecto factible, con investigación de campo, documental y no experimental, se abordó el Modelo General de Desarrollo Tecnológico (MGDT de Szczurek (1990, el cual está constituido por cuatro fases: Estudio de Necesidades, Diseño de la Solución, Implantación y Evaluación. Los sujetos de investigación fueron  16 estudiantes con discapacidad, y 19 profesores del Departamento de Tecnología Educativa del IPC. En la implantación se ejecutó el diseño de la solución, obteniéndose resultados favorables, y posteriormente se procedió a la evaluación de todas las fases.

  7. Herencia del número de vainas por nudo y su relación con características afines en arveja (Pisum sativum L.

    Directory of Open Access Journals (Sweden)

    Castillo Edgar

    2014-11-01

    Full Text Available En el año 2010-2011 en el Centro de Investigaciones Fitoecogenéticas de Pairumani (CIFP en Cochabamba-Bolivia, se cruzaron ocho líneas parentales de arveja bajo el diseño dialélico Griffing IV, con el objetivo de determinar las bases genéticas que condicionan el número de vainas por nudo, la relaciones genéticas con caracteres afines y las líneas que posean genes favorables para incrementar el número de vainas por nudo. Las progenies F1 evaluadas de acuerdo al diseño experimental de filas y columnas incompletas con cuatro repeticiones, indican que el número de vainas/nudo está condicionado por efectos aditivos y de dominancia; sin embargo, los efectos aditivos fueron de mayor importancia con una heredabilidad en sentido estrecho moderado (0.49. Por otro lado, el número de vainas/nudo está alta y positivamente correlacionada con el número de vainas/planta y densidad de grano, en las cuales los efectos aditivos fueron de mayor importancia y heredabilidades en sentido estrecho de 0.72 y 0.36, respectivamente. El número de vainas/nudo está alta y negativamente correlacionada con días a floración, días a madurez en verde, largo de vaina, ancho de vaina, peso de grano, altura de planta y altura a la primera vaina, en las cuales excepto en altura de planta y altura a la primera vaina, los efectos aditivos fueron de mayor importancia, con una heredabilidad en sentido estrecho entre 0.19 y 0.81. Para desarrollar variedades con mayor número de vainas por nudo se puede optar por desarrollar variedades con vainas a menor altura, de granos más pequeños y con vainas más delgadas; o variedades con más días a madurez en verde, de granos menos densos, pedúnculo corto y vainas cortas. Las líneas M-2, calle-calle, Pairumani-1, PH-91-3 poseen genes favorables para desarrollar variedades con mayor número de vainas por nudo y por ende mayor cantidad de vainas por planta, pero con vainas pequeñas y delgadas, y de ciclo corto, además de

  8. Diagnóstico educativo sobre salud bucal en embarazadas y madres con niños menores de un año

    Directory of Open Access Journals (Sweden)

    Judit Martínez Abreu

    Full Text Available Introducción: la atención estomatológica en Cuba prioriza a embarazadas y madres con niños menores de un año. Objetivo: identificar los conocimientos sobre salud bucal de embarazadas y madres con niños menores de un año. Métodos: se realizó un estudio observacional, descriptivo y transversal, en el municipio Matanzas de 2010 a 2012. El universo fueron todas las embarazadas y madres con niños menores de un año. Se seleccionó una muestra no probabilística con las primeras 126 gestantes captadas y 126 madres que acudieran a puericultura, que dieron su consentimiento informado. Se aplicó la encuesta de conocimientos del Programa Nacional de Atención Estomatológica Integral a la Población y una lluvia de ideas para identificar los conocimientos favorables o no a la salud bucal, en relación a cuatro temas: caries dental, periodontopatías, brote dentario y maloclusiones. Se consideró el nivel de conocimientos bajo (menos de 70 puntos, medio (entre 71 y 89 puntos y alto (más de 90 puntos. Los datos obtenidos fueron procesados estadísticamente, se usó el porcentaje como medida de resumen. Resultados: entre los conocimientos favorables a la salud bucal estuvieron los relacionados con las medidas preventivas de caries dental y periodontopatías, como el cepillado, con 85,7 % en embarazadas y 95,2 % en madres con niños menores de un año. Los conocimientos desfavorables fueron los relacionados con el brote dentario con 96 % en embarazadas y 94,4 % en madres con niños menores de un año. Las madres con niños menores de un año, mostraron nivel de conocimientos medio (70,6 %, mientras que las embarazadas, mostraron nivel bajo (65,9 %. Conclusiones: las madres con niños menores de un año mostraron nivel de conocimientos sobre salud bucal, medio y las embarazadas mostraron un nivel bajo. Los conocimientos sobre brote dentario y maloclusiones fueron insuficientes, por lo que serán las principales temáticas para desarrollar

  9. Does food insecurity compromise maternal dietary Zinc or energy intake in favor of her child, in rural poor Mexican households? ¿En hogares rurales pobres de México, la inseguridad alimentaria compromete el consumo de zinc y energía de las madres en favor de sus hijos?

    Directory of Open Access Journals (Sweden)

    Karla Moreno-Tamayo

    2011-08-01

    Full Text Available OBJECTIVE: To analyze quantitative indicators of food insecurity (FI, and estimate if FI modifies the association between maternal and child Zinc and energy intake as evidence for maternal dietary compromise in favor of her child. MATERIAL AND METHODS: Cross-sectional study (n=2 563, data derived from baseline impact evaluation of the Mexican Programa de Apoyo Alimentario. Quantitative indicators of FI were:Household food storage, maize and/or bean production, food expenditure, and spatial access to food markets. We evaluated percentage adequacy of energy (PAE and Zinc (PAZn intake. Multiple linear regression model was fitted to estimate the association between maternal and child PAE and PAZn. RESULTS: Child PAE and PAZn were positively associated with those of their mothers. None of the FI indicators modified the association between maternal and child PAE and PAZn. CONCLUSIONS: No evidence of maternal dietary compromise in favor of her child was observed using four quantitative indicators of FI in central-southern rural Mexican househods.OBJETIVO: Analizar indicadores cuantitativos de inseguridad alimentaria (IA y estimar si IA modifica la asociación del consumo de energía y zinc en madres e hijos como evidencia del compromiso de la dieta materna a favor de su hijo. MATERIAL Y MÉTODOS: Estudio transversal,información basal de la evaluación de impacto del Programa de Apoyo Alimentario. Indicadores de IA: reserva de alimentos en hogar, autoproducción maíz y/o frijol, porcentaje del gasto en alimentos y acceso físico a mercados de alimentos.Se calculó el porcentaje de adecuación del consumo energético (PAE y Zinc (PAZn (n=2 563 pares. Se estimó un modelo de regresión lineal ajustado por covariables. RESULTADOS: El PAE y PAZn de madres e hijos se asoció positivamente. Ningún indicador de IA modificó la asociación entre PAE y PAZn materno con respecto a sus hijos. CONCLUSIONES: Los indicadores de IA estudiados no modifican la relaci

  10. Rabdomiolisis asociada al tratamiento con valaciclovir

    Directory of Open Access Journals (Sweden)

    Héctor Enríquez Gómez

    2012-03-01

    Full Text Available La rabdomiolisis es un efecto secundario asociado a un buen número de fármacos, entre ellos los antivirales. Describimos un caso de rabdomiolisis secundaria a valaciclovir, efecto no descrito anteriormente en laliteratura, en un contexto clínico muy especial. Se trata de un varón queingresa por un golpe de calor secundario a la realización de ejercicio físicoextremo. Durante su ingreso se comienza tratamiento con valaciclovir porun herpes nasolabial, observándose en los días siguientes una marcadaelevación de las cifras de CPK que desaparece con la suspensión del mismo. Proponemos, por tanto, que ante la administración de valaciclovir ensituaciones que puedan comportar daño mitocondrial habría que realizarmonitorización estrecha de los niveles de CPK

  11. Experiencias y aprendizajes con juegos cooperativos

    Directory of Open Access Journals (Sweden)

    Evelyn Cerdas Agüero

    2013-03-01

    Full Text Available El presente trabajo tiene como objetivo presentar experiencias y aprendizajes que  han logrado algunos grupos de docentes con los que se ha trabajado por medio de talleres de juegos cooperativos para la paz. Los talleres se han facilitado desde la actividad de extensión Aula Activa: juegos cooperativos para la Educación para la Paz que se ha implementado en el  Instituto de Estudios Latinoamericanos (IDELA desde el 2006. En este trabajo  nos enfocamos en el trabajo con docentes del Ministerio de Educación Pública (MEP de Costa Rica, proceso que deja una serie de aprendizajes actitudinales, de valores, habilidades y cognocitivos.

  12. Comunicándonos con las cosas

    Directory of Open Access Journals (Sweden)

    Miguel Delgado

    2009-09-01

    Full Text Available Tras la Web 2.0 y gracias a la colaboración entre las personas, Internet sigue creciendo y evolucionando, pero esta vez a través de los objetos. La siguiente evolución pretende que las personas puedan interactuar con las cosas de una forma inteligente mediante tecnologías ampliamente utilizadas como el teléfono móvil e Internet, y tecnologías que permitan etiquetar objetos.

  13. Bacteriemia en pacientes internados con celulitis

    Directory of Open Access Journals (Sweden)

    Juan S. Lasa

    2012-08-01

    Full Text Available La celulitis es una inflamación aguda de la dermis y tejido celular subcutáneo de causa bacteriana, que generalmente complica a heridas, úlceras y dermatosis, aunque de manera frecuente no existe sitio de entrada. Se recomienda la realización de cultivo de punción de piel y partes blandas (PPB. Los hemocultivos raramente dan resultados positivos. El objetivo de este trabajo fue determinar la prevalencia de bacteriemia en pacientes internados en nuestra institución con diagnóstico de celulitis. Se analizaron retrospectivamente los registros clínicos de los pacientes con este diagnóstico al ingreso entre junio de 2007 y marzo de 2010. Se evaluaron los datos poblacionales, presencia de comorbilidades, y resultados de los cultivos. En ese período, se internaron 140 pacientes con diagnóstico de celulitis y a todos ellos se les realizó hemocultivo y cultivos de PPB. Setenta y cuatro eran varones (52.8%. La edad promedio: 47.5 ± 19.7 años (rango 16-94. El 40% tuvo cultivos positivos de PPB, en los que el Staphylococcus aureus meticilino resistente (SAMR fue el germen más frecuentemente aislado (35.7%; la prevalencia de bacteriemia fue del 8.6%, en donde el germen más frecuente fue Streptoccocus Beta hemolítico, grupo G (33% del total de hemocultivos positivos. La bacteriemia se asoció significativamente a mayor estadía hospitalaria (10.5 ± 8.9 vs. 4.9 ± 6, p = 0.004. Se asoció con mayor riesgo de hemocultivo positivo a ser diabético, tener cultivo de PPB positivo, consumo de alcohol y/o enfermedad pulmonar obstructiva crónica.

  14. Radiation therapy for chest wall recurrence of breast cancer after mastectomy in a favorable subgroup of patients

    International Nuclear Information System (INIS)

    Hsi, R. Alex; Antell, Andrew; Schultz, Delray J.; Solin, Lawrence J.

    1998-01-01

    Purpose: Long-term outcome after radiation therapy for local-regional recurrence of breast cancer after mastectomy is generally poor. This study was performed to evaluate the long-term outcome for a potentially favorable subgroup of patients with chest wall recurrence. Methods and Materials: Of 71 patients with an isolated local-regional recurrence of breast cancer after mastectomy, 18 were identified who met the following favorable selection criteria: 1) a disease-free interval after mastectomy of 2 years or more, 2) an isolated chest wall recurrence, and 3) tumor size < 3 cm or complete excision of the recurrent disease. All 18 patients were treated with local-regional irradiation between 1967 and 1988. Radiotherapy (RT) was delivered to the chest wall to a median total dose of 60 Gy (range 30-66 Gy). Four patients received adjuvant chemotherapy and six patients received adjuvant hormonal therapy. Results: With a median follow-up of 8.4 years, nine of 18 patients were alive and free of disease. The 10-year actuarial overall and cause-specific survivals were 72% and 77%, respectively. The 10-year actuarial relapse-free survival and local control were 42% and 86%, respectively. Conclusion: Treatment for a local-regional recurrence of breast cancer after mastectomy in a favorable subgroup of patients results in a high rate of long-term survival as well as excellent local control. Aggressive treatment is warranted in this favorable subgroup of patients. 1998 Elsevier Science Inc

  15. Explaining financial and prosocial biases in favor of attractive people: Interdisciplinary perspectives from economics, social psychology, and evolutionary psychology.

    Science.gov (United States)

    Maestripieri, Dario; Henry, Andrea; Nickels, Nora

    2017-01-01

    Financial and prosocial biases in favor of attractive adults have been documented in the labor market, in social transactions in everyday life, and in studies involving experimental economic games. According to the taste-based discrimination model developed by economists, attractiveness-related financial and prosocial biases are the result of preferences or prejudices similar to those displayed toward members of a particular sex, racial, ethnic, or religious group. Other explanations proposed by economists and social psychologists maintain that attractiveness is a marker of personality, intelligence, trustworthiness, professional competence, or productivity. Evolutionary psychologists have argued that attractive adults are favored because they are preferred sexual partners. Evidence that stereotypes about attractive people are causally related to financial or prosocial biases toward them is weak or nonexistent. Consistent with evolutionary explanations, biases in favor of attractive women appear to be more consistent or stronger than those in favor of attractive men, and biases are more consistently reported in interactions between opposite-sex than same-sex individuals. Evolutionary explanations also account for increased prosocial behavior in situations in which attractive individuals are simply bystanders. Finally, evolutionary explanations are consistent with the psychological, physiological, and behavioral changes that occur when individuals are exposed to potential mates, which facilitate the expression of courtship behavior and increase the probability of occurrence of mating. Therefore, multiple lines of evidence suggest that mating motives play a more important role in driving financial and prosocial biases toward attractive adults than previously recognized.

  16. Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older

    NARCIS (Netherlands)

    Beesems, Stefanie G.; Blom, Marieke T.; van der Pas, Martine H. A.; Hulleman, Michiel; van de Glind, Esther M. M.; van Munster, Barbara C.; Tijssen, Jan G. P.; Tan, Hanno L.; van Delden, Johannes J. M.; Koster, Rudolph W.

    2015-01-01

    Advanced age is reported to be associated with lower survival after out-of-hospital cardiac arrest (OHCA). We aimed to establish survival rate and neurological outcome at hospital discharge after OHCA in older patients and evaluated whether pre-OHCA comorbidity was associated with favorable

  17. Preliminary study of uranium favorability of upper cretaceous, paleocene, and lower eocene rocks of the Bighorn Basin, Wyoming and Montana

    International Nuclear Information System (INIS)

    Hesse, S.L.; Dunagan, J.F. Jr.

    1978-02-01

    This report presents an evaluation of the uranium favorability of continental sediments of the Upper Cretaceous Lance, Paleocene Polecat Bench, and lower Eocene Willwood Formations in the Bighorn Basin of Wyoming and Montana, an intermontane structural basin of Laramide age. Previous work dealing with the Bighorn Basin was reviewed, and field investigations were carried out in the spring and summer of 1976. Subsurface data were collected and results of surface and subsurface investigations were evaluated with respect to uranium favorability. Precambrian plutonic and metamorphic rocks and Tertiary tuffaceous rocks in the Bighorn Basin and bordering uplifts are considered insignificant as source rocks, although the Wiggins Formation (White River equivalent) cannot be evaluated as a possible source because of a lack of data. Potential host rocks locally show only limited favorability. Lithology of strata exposed along the western and southern basin margins is more favorable than that of rocks in the central and eastern parts of the basin, but there is little organic material, pyrite, or other reducing agents in these rocks. Strata of the Lance, Polecat Bench, and Willwood Formations in the Bighorn Basin are considered generally unfavorable for sandstone uranium deposits

  18. The Bias in Favor of Venture Capital Finance in U.S. Entrepreneurial Education: At the Expense of Trade Credit

    Science.gov (United States)

    Clement, Thomas; LeMire, Steven; Silvernagel, Craig

    2015-01-01

    The authors examine whether U.S. college-level entrepreneurship education demonstrates a bias favoring venture capital (VC) financing while marginalizing trade credit financing, and the resulting impact on entrepreneurship students. A sample of U.S. business textbooks and survey data from entrepreneurship students reveals a significant bias toward…

  19. ORIENTACIONES CURRICULARES CON EL ENFOQUE CTS

    Directory of Open Access Journals (Sweden)

    Miguel Corchuelo

    2010-11-01

    Full Text Available Considerando que el propósito de la educación con un enfoque CTS propende por abordar problemas contextualizados socialmente, se busca construir una propuesta desde la práctica, con el fi n de fortalecer la formación para la participación ciudadana. Encontramos que abordar el tratamiento de las relaciones entre deporte, nutrición humana y motricidad convierte al cuerpo humano en un objeto de estudio vigente. En la ciudad de Popayán (Cauca, Colombia se vive una de las más altas tasas de bulimia y anorexia en adolescentes del país, al igual que de consumo de drogas ilícitas. Además, el bajo rendimiento de los deportistas caucanos en los últimos Juegos Nacionales, los casos de dopaje en atletas olímpicos, entre otros, abre interrogantes sobre la formación integral de nuestros estudiantes. Con el fi n de acercar la escuela a estas problemáticas locales y nacionales, se asume un trabajo interdisciplinario basado en la resolución de problemas socialmente relevantes. En esta oportunidad compartiremos los resultados del camino recorrido en torno a la pregunta: “El deporte: ¿emancipación o alienación?”.

  20. Aprendiendo química con golosinas

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    José Manuel Rodríguez Rodríguez

    2011-01-01

    Full Text Available Las golosinas (caramelos, chicles, nubes, palotes, papas fritas, etc. nos gustan a casi todos y gozan de una imagen positiva, a pesar de sus efectos secundarios si no se consumen con moderación. Aprovechándonos de esa buena imagen y de la gran variedad de golosinas que existen en el mercado, hemos diseñado una serie de experimentos con los que podemos explicar distintos tipos de reacciones químicas (ácido-base, oxidación reducción, endotérmicas¿, la actuación de un indicador e, incluso, podemos comparar cantidades de vitamina C. En todas las actividades se persigue explicar algún aspecto de la Química que, en general, el público desconoce, captando su atención, por ejemplo, mediante cambios de color espectaculares y con las golosinas como protagonistas. Así mismo, estas experiencias pueden emplearse como recursos didácticos para alumnos de 4º E.S.O. y Bachillerato, apoyando los contenidos teóricos del currículum.

  1. Preferential uptake of ribose by primitive cells might explain why RNA was favored over its analogs

    Science.gov (United States)

    Pohorille, Andrew; Wei, Chenyu

    perme-ation, even though it is non-negligibly populated in aqueous solution. The differences in free energy barrier between ribose and arabinose or xylose are due to stronger, highly cooperative, intramolecular interactions between consecutive exocyclic hydroxyl groups, which are stable in non-polar media, but rare in water. Most recently, we extended calculations of permeations to ribonucleosides and their anomers. We determined that, in contrast to sugars, permeation of membranes to these species is nearly identical. This is because sugars of nucleotides exist in the furanose rather than pyranose form. In this form intermolecular interactions between hydroxyl groups are not nearly as efficient for sterical reasons. Our results contribute to the discussion about autotrophic vs. heterotrophic origins of life. Chemical reactions inside protobiological vesicle required supply of organic material from the environment. What was the inventory of organics that must have been delivered to primitive cells is still being debated. According to the autotrophic hypothesis, ancestors of cells pro-duced complex organic molecules from simple substrates. In contrast, the heterotrophic model implies that protocells were able to utilize complex organics delivered from external sources. A possibility of sufficiently efficient uptake of molecules needed to build biopolymers provides an important argument supporting the heterotrophic hypothesis [3]. Viewed in the context of the "RNA world" hypothesis [4], which states that RNA molecules were the first biological poly-mers and acted as both catalysts of biochemical reactions and information storage systems, our results demonstrate that, in the absence of sophisticated mechanisms available to contemporary organisms for achieving selectivity during synthesis and transmembrane transport, preferential uptake of ribose by primitive cells might have provided a kinetic mechanism that favored its selective incorporation into nucleic acids and

  2. Effect of edaravone on favorable outcome in patients with acute cerebral large vessel occlusion: subanalysis of RESCUE-Japan Registry.

    Science.gov (United States)

    Miyaji, Yuki; Yoshimura, Shinichi; Sakai, Nobuyuki; Yamagami, Hiroshi; Egashira, Yusuke; Shirakawa, Manabu; Uchida, Kazutaka; Kageyama, Hirohito; Tomogane, Yusuke

    2015-01-01

    The data of the nationwide prospective registry of acute cerebral large vessel occlusion (LVO; RESCUE-Japan Registry) were analyzed to know the effect of edaravone, a free radical scavenger, on clinical outcome at 90 days after onset. In this registry, patients with acute cerebral LVO admitted within 24 h after onset were prospectively registered. The effect of various factors including endovascular treatment (EVT), intravenous recombinant tissue plasminogen activator (IV rt-PA), and other medication including edaravone on favorable outcome (modified Rankin scale 0-1) was analyzed. Of the 1,454 registered patients, 1,442 patients (99.2%) had the information of edaravone were analyzed. In total, edaravone group had more patients with favorable outcome compared to non-edaravone group (22.9% vs. 13.8%, p = 0.0006). Edaravone increased favorable outcome in patients treated with IV rt-PA (29.4% vs. 11.1%, p = 0.0107), but not with EVT (21.2% vs. 13.9%, p = 0.309). Logistic regression analysis revealed that higher National Institutes of Health Stroke Scale (NIHSS) score on admission [odds ratio (OR) 0.875, 95% confidence interval (CI) 0.858-0.894] and advanced age (OR 0.963, 95%CI 0.952-0.975) were significantly related to unfavorable outcome. In contrast, IV rt-PA (OR 2.489, 95%CI 1.867-3.319), EVT (OR 1.375, 95%CI 1.013-1.865), and edaravone (OR 1.483, 95%CI 1.027-2.143) were significantly associated with favorable outcome. This analysis indicated that IV rt-PA, EVT, and edaravone were effective to obtain favorable outcome in patients with acute LVO. Combination IV rt-PA with edaravone was more effective.

  3. Calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes LADA

    OpenAIRE

    Granado Casas, Minerva

    2014-01-01

    Introducción: La calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes mellitus están relacionados con el control metabólico, las complicaciones y algunas variables socioeconómicas. Actualmente, no existe ningún estudio científico que analice la calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes LADA. Objetivos: Los objetivos principales fueron conocer la calidad de vida, satisfacción con el tratamient...

  4. "Sonríe con salud"

    Directory of Open Access Journals (Sweden)

    Rosa María González Ramos

    Full Text Available Introducción: los programas educativos juegan un papel importante ya que permiten modificar hábitos y conductas perjudiciales para la salud. Las personas de la tercera edad deben adquirir los conocimientos necesarios para realizar el auto cuidado de la salud bucal mejorando así su calidad de vida. Objetivo: evaluar los resultados del programa "Sonríe con salud". Métodos: se realizó una investigación descriptiva de corte transversal, con un universo de 74 personas de 60 años y más. Las variables estudiadas fueron: la edad, sexo. Se aplicó una encuesta. Las respuestas se agruparon atendiendo a si poseían o no, conocimientos acerca de la relación entre salud bucal y salud general, las principales enfermedades buco-dentales, realización del autoexamen bucal, efecto del tabaquismo y alcoholismo, ingestión de los alimentos azucarados, calientes, picantes y la importancia de la higiene bucal. La recolección de la información, la realizaron los autores empleando como fuente primaria el cuestionario aplicado en la primera etapa de la investigación. Se utilizaron los valores absolutos y el porcentaje en el análisis de los resultados. Resultados: el grupo de edad de 70 a 79 años fueron los más representados (36,5 % y el sexo femenino con un 59,5 %. Se elevaron los conocimientos relacionados con el efecto perjudicial del alcoholismo al 91,9 % y el tabaquismo al 95,9 %; acerca de la ingestión de alimentos azucarados se elevan al 97,7 % al igual que los alimentos calientes y picantes en un 90,5 %, relativo al autoexamen bucal se superan los conocimientos de su realización al 78,4 % y referente a la higiene bucal se elevan al 91,9 %. Conclusiones: el programa educativo "sonríe con salud" resultó eficaz, al elevar el nivel de conocimientos de los ancianos que recibieron las actividades previstas en el programa.

  5. Acogida de los solicitantes de asilo con discapacidad en Europa

    OpenAIRE

    Beduschi-Ortiz, Ana

    2010-01-01

    Con respecto a la acogida de los solicitantes de asilo en la Unión Europea, podemos encontrar disposiciones para la protección de las personas con discapacidad en una amplia gama de fuentes reguladoras.

  6. Factores asociados con la irregularidad de la ingesta de Dapsona en pacientes con lepra: Dapsona en pacientes con lepra

    Directory of Open Access Journals (Sweden)

    Luis Carlos Orozco Vargas

    2013-04-01

    Full Text Available Introducción: Conocer los factores asociados al cumplimiento del tratamiento en pacientes con lepra, es muy importante para prevenir la resistencia del Mycobacterium leprae y garantizar la cura bacteriológica de estas personas. La prueba de orina para Dapsona, presente en el régimen autoadministrado, es un método sencillo para establecer la regularidad del tratamiento. Objetivo: Explorar los factores asociados a la irregularidad de la ingesta del tratamiento antileproso. Métodos: Estudio de corte transversal de los enfermos que recibieron tratamiento antileproso en un centro dermatológico. La irregularidad se estableció con la prueba de dapsonuria. Se consideró irregular el que presentó la prueba negativa. Las variables sospechosas de influir en la irregularidad se analizaron con regresión logística exacta. Resultados: En el modelo final del análisis multivariado se encontraron cinco variables asociadas, entre éstas sobresalen como factores de riesgo, la ausencia de discapacidad, OR 28.56 (IC90% 1.2-2.1 y la entrega de tratamiento para tiempos mayores a un mes, por cada mes OR 3.41 (IC90% 1.4-9.2 y como factor protector, la aceptación familiar de la enfermedad OR 0.008 (IC90% 0.001-0.24. Conclusión: Aunque es posible que el pequeño tamaño de muestra no haya permitido detectar algunos factores de riesgo informados en otras investigaciones, la mayoría de esos estudios no han realizado análisis multivariado por lo cual es posible que muchos de los factores informados en la literatura no tengan importancia. Salud UIS 2013; 45 (1: 7-14

  7. 9 CFR 319.301 - Chili con carne with beans.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Chili con carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili con carne with beans. Chili con carne with beans shall contain...

  8. Insuficiencia renal aguda relacionada con medicamentos en pacientes hospitalizados

    Directory of Open Access Journals (Sweden)

    Lujan Iavecchia

    2015-11-01

    Conclusiones: La mitad de los episodios de IRA intrahospitalaria se relacionaron con medicamentos. Los pacientes con IRA relacionada con medicamentos presentaron más antecedentes patológicos cardiovasculares, pero menos factores de riesgo de IRA y una menor mortalidad.

  9. Sex Differences and Bone Metastases of Breast, Lung, and Prostate Cancers: Do Bone Homing Cancers Favor Feminized Bone Marrow?

    Directory of Open Access Journals (Sweden)

    Mary C. Farach-Carson

    2017-08-01

    Full Text Available Sex-associated differences in bone metastasis formation from breast, lung, and prostate cancer exist in clinical studies, but have not been systematically reviewed. Differences in the bone marrow niche can be attributed to sexual dimorphism, to genetic variations that affect sex hormone levels, or to the direct effects of sex hormones, natural or exogenously delivered. This review describes the present understanding of sex-associated and sex hormone level differences in the marrow niche and in formation of bone metastasis during the transition of these three cancers from treatable disease to an often untreatable, lethal metastatic one. Our purpose is to provide insight into some underlying molecular mechanisms for hormonal influence in bone metastasis formation, and to the potential influence of sexual dimorphism, genetic differences affecting sex assignment, and sex hormone level differences on the bone niche and its favorability for metastasis formation. We reviewed publications in PubMed and EMBASE, including full length manuscripts, case reports, and clinical studies of relevance to our topic. We focused on bone metastasis formation in breast, lung, and prostate cancer because all three commonly present with bone metastases. Several clear observations emerged. For breast cancer bone metastasis formation, estrogen receptor (ER signaling pathways indicate a role for ER beta (ERβ. Estrogen influences the bone microenvironment, creating and conditioning a favorable niche for colonization and breast cancer progression. For lung cancer, studies support the hypothesis that females have a more favorable bone microenvironment for metastasis formation. For prostate cancer, a decrease in the relative androgen to estrogen balance or a “feminization” of bone marrow favors bone metastasis formation, with a potentially important role for ERβ that may be similar to that in breast cancer. Long-term estrogen administration or androgen blockade in males

  10. Tratamiento de la obesidad con productos naturales

    Directory of Open Access Journals (Sweden)

    Lina Neri Espinosa Pire

    2016-12-01

    Full Text Available Los crecientes índices de obesidad alrededor del mundo, provocados principalmente por los excesos en la ingesta y la vida sedentaria, constituye uno de los grandes problemas de salud pública en nuestras sociedades. Entre otras formas como dietas y tratamientos que surgen cada día para combatir la obesidad, el uso de plantas medicinales conocido como fitoterapia, ha despertado gran interés. Existen ciertas plantas que poseen propiedades adelgazantes, sin embargo, lo mejor es ponerse en manos de especialistas en este campo, para recibir una correcta asesoría de acuerdo a las necesidades personales. Las plantas medicinales y los productos que de ellas se obtienen, constituyen remedios eficaces para combatir la obesidad, pues no tienen efectos adversos. No obstante el tratamiento debe combinarse con un cambio de hábitos alimentarios y actividad física y no conviene utilizarlos irresponsablemente, pues no todos tienen los mismos beneficios y efectos. La eficacia de la aplicación de plantas con la finalidad de bajar de peso ha sido comprobada en numerosos ensayos clínicos que se han realizado con determinadas especies vegetales. Las plantas medicinales se han utilizado tradicionalmente en forma de infusión, sin embargo esta forma de administración no permite controlar efectivamente las dosis administradas, por lo que es preferible hacerlo en preparados como cápsulas o comprimidos. Cada planta deberá administrarse de una manera específica y es importante que los preparados se tomen siempre en el mismo horario para potenciar su efectividad.

  11. Factores prenatales relacionados con la prematuridad

    Directory of Open Access Journals (Sweden)

    Guillermo Arias Macías

    2001-03-01

    Full Text Available Se estudiaron 130 madres y sus recién nacidos prematuros con su correspondiente grupo control, nacidos en el Hospital Ginecoobstétrico Provincial Docente "Justo Legón Padilla", de Pinar del Río, desde febrero hasta julio de 1998, con el objetivo de analizar algunos factores perinatales relacionados con la prematuridad. Se analizaron las variables: edad materna, paridad, peso al inicio del embarazo, talla materna, período intergenésico, edad gestacional, oligoamnios, hipertensión arterial materna y sexo del niño. Se demostró que la edad materna inferior a 17 años, la baja talla materna, el oligoamnio, la sepsis ovular y el período intergenésico de más de 5 años tuvieron resultados significativos para el nacimiento de pretérminos.130 mothers and their premature infants with their corresponding control group delivered at "Justo Legón Padilla" Provincial Gynecoobstetric Teaching Hospital, in Pinar del Río, from February to July, 1998, were studied aimed at analyzing some perinatal factors connected with prematurity. The following variables were analyzed: maternal age, parity, weight at the beginning of pregnancy, maternal height, intergenesic period, gestational age, oligohydramnios, maternal hypertension and sex of the child. It was proved that maternal age under 17, low maternal height, the oligohydramnios, vulvar sepsis and the intergenesic period of more than 5 years had significant results for the birth of preterm infants.

  12. Rescate articular con colgajo anterolateral del muslo

    Directory of Open Access Journals (Sweden)

    F.J. García-Bernal

    2015-06-01

    Full Text Available La preservación del nivel de amputación tanto de la extremidad superior como de la inferior, puede mejorar la función residual y el proceso de rehabilitación protésica de la misma. Ambas van a estar condicionadas por la longitud restante de la extremidad, la presencia o no de articulaciones operativas y la calidad de la cobertura del muñón. Presentamos 2 casos de amputaciones. El primero es un caso agudo de amputación traumática de extremidad superior a la altura del tercio proximal de antebrazo, que asocia avulsión cutánea circular desde el tercio medio del brazo y con articulación de codo conservada. El segundo, es la secuela de una amputación infracondílea de extremidad inferior por osteosarcoma que presenta fístulas cutáneas con drenaje supurativo por osteomielitis en el muñón tibial. En ambos pacientes realizamos cobertura con colgajo anterolateral de muslo anastomosado a la arteria radial en el caso de la extremidad superior, y a la arteria genicular descendente en la extremidad inferior. En los dos casos el postoperatorio transcurrió sin complicaciones, logrando preservar las articulaciones del codo y de la rodilla respectivamente, así como la posterior rehabilitación protésica. Consideramos que el colgajo anterolateral del muslo permite aportar tejido de buena calidad como cobertura del muñón de amputación. Dadas las características del tejido aportado y su volumen, es idóneo tanto para cobertura de defectos agudos como de déficits de almohadillado en casos crónicos.

  13. Ceba de novillos en confinamiento con ensilaje de maíz suplementado con torta de girasol

    Directory of Open Access Journals (Sweden)

    Sánchez G. Hugo

    1989-06-01

    Full Text Available En la Hacienda "La Providencia", se evaluó la ceba en confinamiento en condiciones comerciales: se utilizó un arreglo factorial de 2 x 2: dos grupos de animales (livianos de 303 kg y pesados de 368 kg y dos niveles de suplementación proteica con torta de girasol (O y 1 kg/ animal/día, resultando cuatro tratamientos, cada uno con 20 animales. El ensayo duró 125 días y la dieta básica estuvo constituida por ensilaje de maíz, bagacillo de caña predigerido al 3 % de Na OH, melaza de caña, úrea, vitaminas y sal común al 8.5 % P a voluntad. Los animales se implantaron con Zeranol. Los consumos de materia seca/animal/grupo fueron de 7.9, 8.0, 9.4 y 9.1 kg/día., para los tratamientos 1 al 4 respectivamente. El tratamiento 1 fue el más favorable económicamente, seguido por 105 tratamientos 3, 2 y 4. Los tratamientos 2,3 y 4 generaron mayores gastos que ingresos; sin embargo, cuando se incluyó toda la operación, el valor de las ventas brutas fue mayor que los costos variables, presentándose en todos los tratamientos una diferencia positiva. Esto debido a que el valor de los novillos aumentó de un precio de compra a uno de venta durante el período que duró el experimento, por lo tanto, los retornos brutos fueron mayores que 105 costos variables, subsidiando la pérdida debida a que la alimentación estaba costando más, que el valor obtenido por los aumentos de peso conseguido por los animales.A trial with beef steers was conducted to evaluate a fattening feeding regime under commercial conditions. Two groups of animals were used (303 kg the light weight and 368 kg the heavy weight and two protein supplement levels (zero and one kg / animal/day; in a 2 x 2 factorial with tour treatments (TRT, each with 20 animals. The duration of the experiment was 125 days and the basal diet consisted of cornsilage, sugar caña bagassepith treated with 13 % Na OH, caña molasses, urea, vitaminas and comun salt with 8.5 % P offered at will. The animals

  14. Proyecto innovador: “con+ciencia”

    OpenAIRE

    Fernández Arroyo, Jorge; Rodríguez Marín, Fátima; González Medina, Sara

    2013-01-01

    En esta comunicación se expone la experiencia de observación sobre el funcionamiento del proyecto Con+ciencia en los cursos de 5º y 6º de Primaria (tercer ciclo) del centro C.E.I.P. “Príncipe de Asturias” (Sevilla) durante el mes de marzo del 2013. Nuestra participación ha buscado conocer en profundidad este proyecto, observar su aplicación real en el aula y sus implicaciones en el alumnado y el profesorado.

  15. Riego subsuperficial con aguas residuales tratadas

    OpenAIRE

    Crespi, Raúl; Camacho, Emilio; Polo, María José

    2009-01-01

    La reutilización de aguas residuales tratadas para riego por goteo subsuperficial (RGS) de cultivos extensivos, es una práctica reconocida mundialmente, siendo la obturación de emisores un serio problema en la operación de estos sistemas. Durante el ciclo agrícola 2002/03, se realizó un ensayo experimental usando dos tipos de agua: limpia (AL) y residual tratada (AR) en un sistema mixto combinando un reactor biológico con laguna de maduración y tres tipos de protectores del emisor: micro dosi...

  16. Biorremediacion de suelos contaminados con hidrocarburos

    OpenAIRE

    Ortiz, E.; Núñez, R.; Fonseca, E.; Oramas, J.; Almazán, V.; Cabranes, Y.; Miranda, A.; Barbán, O.; Martínez, C.; Díaz, Y.; Borges, G.

    2005-01-01

    En la actualidad los suelos contaminados con hidrocarburos representan el 70% del total de los eco-sistemas impactados. A partir del aislamiento, selección y conservación de bacterias marinas degra-dadoras de hidrocarburos y productoras de sustancias tensioactivas se formuló un producto denomi-nado BIOIL-FC. Este producto ha sido aplicado satisfactoriamente en derrames de hidrocarburos en el mar. En el presente trabajo fue evaluada la factibilidad del uso de los procesos de biorremediación “e...

  17. Los juegos de Borges con el tiempo

    Directory of Open Access Journals (Sweden)

    Paulína Šišmišová

    2012-12-01

    Full Text Available La preocupación por el tiempo es una de las constantes de la obra del escritor argentino Jorge Luis Borges. Los «juegos con el tiempo» forman parte indispensable de sus estrategias narrativas, tal como lo documenta también su célebre cuento «Borges y yo». En nuestra contribución nos dedicaremos a estudiar la problemática del tiempo en Borges bajo dos aspectos: el tiempo como recurso de configuración del texto narrativo y el tiempo como categoria metafísica.

  18. Tratamiento de aguas contaminadas con cianuro

    OpenAIRE

    Aguilar Roca, Fernando; Aguilar Roca, Fernando; Aguilar Roca, Fernando

    2011-01-01

    El presente trabajo “Tratamiento de aguas contaminadas con cianuro" se divide en tres partes: química del contaminante, procesos de descontaminación estudiados y un procedimiento basado en una investigación reciente. Principales propiedades físico-químicas del ion cianuro y de sus principales compuestos, cianuros simples o complejos, en medio acuoso. Métodos y procesos que existen para la descontaminación de efluentes cianurados, tanto los que se dan de forma natural (degradación natu...

  19. Las personas con discapacidad en el cine

    OpenAIRE

    Monjas, M.I.; et al.

    2005-01-01

    Una forma de comprobar cómo se conceptualiza a las personas con discapacidad es analizar la imagen que de ellas se refleja en distintos soportes como pueden ser libros, prensa y medios de comunicación. El presente trabajo se centra en el estudio de películas cuyos protagonistas tienen alguna discapacidad. A tal efecto, y después de revisar una parte de la producción cinematográfica, se han seleccionado cincuenta películas para proceder a su análisis. Los resultados obtenidos evidencian la esc...

  20. Collective Nostalgia Is Associated With Stronger Outgroup-Directed Anger and Participation in Ingroup-Favoring Collective Action

    Directory of Open Access Journals (Sweden)

    Wing-Yee Cheung

    2017-08-01

    Full Text Available Collective nostalgia refers to longing for the way society used to be. We tested whether collective nostalgia is associated with ingroup-favoring collective action and whether this association is mediated by outgroup-directed anger and outgroup-directed contempt. We conducted an online study of Hong Kong residents (N = 111 during a large-scale democratic social movement, the Umbrella Movement, that took place in Hong Kong in 2014 in response to proposed electoral reforms by the Chinese government in Mainland China. Reported collective nostalgia for Hong Kong’s past was high in our sample and collective nostalgia predicted stronger involvement in ingroup-favoring collective action, and it did so indirectly via higher intensity of outgroup-directed anger (but not through outgroup-directed contempt. We argue that collective nostalgia has implications for strengthening ingroup-serving collective action, and we highlight the importance of arousal of group-based emotions in this process.

  1. Addition of granular activated carbon and trace elements to favor volatile fatty acid consumption during anaerobic digestion of food waste.

    Science.gov (United States)

    Capson-Tojo, Gabriel; Moscoviz, Roman; Ruiz, Diane; Santa-Catalina, Gaëlle; Trably, Eric; Rouez, Maxime; Crest, Marion; Steyer, Jean-Philippe; Bernet, Nicolas; Delgenès, Jean-Philippe; Escudié, Renaud

    2018-07-01

    The effect of supplementing granular activated carbon and trace elements on the anaerobic digestion performance of consecutive batch reactors treating food waste was investigated. The results from the first batch suggest that addition of activated carbon favored biomass acclimation, improving acetic acid consumption and enhancing methane production. Adding trace elements allowed a faster consumption of propionic acid. A second batch proved that a synergy existed when activated carbon and trace elements were supplemented simultaneously. The degradation kinetics of propionate oxidation were particularly improved, reducing significantly the batch duration and improving the average methane productivities. Addition of activated carbon favored the growth of archaea and syntrophic bacteria, suggesting that interactions between these microorganisms were enhanced. Interestingly, microbial analyses showed that hydrogenotrophic methanogens were predominant. This study shows for the first time that addition of granular activated carbon and trace elements may be a feasible solution to stabilize food waste anaerobic digestion. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Predicting favorable conditions for early leaf spot of peanut using output from the Weather Research and Forecasting (WRF) model

    Science.gov (United States)

    Olatinwo, Rabiu O.; Prabha, Thara V.; Paz, Joel O.; Hoogenboom, Gerrit

    2012-03-01

    Early leaf spot of peanut ( Arachis hypogaea L.), a disease caused by Cercospora arachidicola S. Hori, is responsible for an annual crop loss of several million dollars in the southeastern United States alone. The development of early leaf spot on peanut and subsequent spread of the spores of C. arachidicola relies on favorable weather conditions. Accurate spatio-temporal weather information is crucial for monitoring the progression of favorable conditions and determining the potential threat of the disease. Therefore, the development of a prediction model for mitigating the risk of early leaf spot in peanut production is important. The specific objective of this study was to demonstrate the application of the high-resolution Weather Research and Forecasting (WRF) model for management of early leaf spot in peanut. We coupled high-resolution weather output of the WRF, i.e. relative humidity and temperature, with the Oklahoma peanut leaf spot advisory model in predicting favorable conditions for early leaf spot infection over Georgia in 2007. Results showed a more favorable infection condition in the southeastern coastline of Georgia where the infection threshold were met sooner compared to the southwestern and central part of Georgia where the disease risk was lower. A newly introduced infection threat index indicates that the leaf spot threat threshold was met sooner at Alma, GA, compared to Tifton and Cordele, GA. The short-term prediction of weather parameters and their use in the management of peanut diseases is a viable and promising technique, which could help growers make accurate management decisions, and lower disease impact through optimum timing of fungicide applications.

  3. The experience of forming a favorable image of the territory through marketing: a review of foreign press

    OpenAIRE

    Bacherikova Mariya L.

    2017-01-01

    A favorable image of the territory is a factor of attracting investors, tourists and labor force. Using of image approach to foreign territory management practice is already producing positive effects, but there are some difficulties in Russia, particularly in the Far East. Authors explore scientific publications in a foreign press, describing various marketing techniques used to territorial image forming in foreign countries. The territorial image is its image from the point of view of diff...

  4. J-ACT II. Differences in rate of valid recanalization and of a favorable outcome by site of MCA occlusion

    International Nuclear Information System (INIS)

    Hirano, Teruyuki

    2010-01-01

    The background and purpose of this study was to elucidate whether the effects of alteplase differ with occlusion site of the middle cerebral artery (MCA). An exploratory analysis was made of 57 patients enrolled on the Japan Alteplase Clinical Trial II (J-ACT II). The residual vessel length (mm), determined on pretreatment MR angiography (MRA), was used to reflect the occluded site. The proportions of patients with valid recanalization (modified Mori grade 2-3) at 6 and 24 hours, and a favorable outcome (modified Rankin scale 0-1 at 3 months) were compared between the groups dichotomized according to their lengths of residual vessel. Multiple logistic regression models were generated to elucidate the predictors of valid recanalization and a favorable outcome. Receiver operating characteristic (ROC) analysis revealed that 5 mm was the practical cutoff length for the dichotomization. In patients with M1 length <5 mm (n=12), the frequencies of valid recanalization at 6/24 hours (16.6%/25.0%) were significantly low compared with those (62.2%/82.2%) of 45 patients with a residual M1 length of ≥5 mm and M2 occlusions (p=0.008 for 6 hours, p<0.001 for 24 hours). The proportion of a favorable outcome was also small in patients with M1 length <5 mm (8.3%), as compared to the others (57.8%, p=0.004). In logistic regression models, the site of MCA occlusion (<5 mm) was the significant predictor of valid recanalization at 6/24 hours and of a favorable outcome. In patients with acute MCA occlusion, residual vessel length <5 mm on MRA can identify poor responders. (author)

  5. Policies in favor of the bicycle development.; Politiques en faveur du developpement du velo. Bonnes pratiques de villes europeennes

    Energy Technology Data Exchange (ETDEWEB)

    Vallar, J.P.; Kerveillan, A.

    2001-07-01

    This study presents, ten cases of european towns which realized a policy in favor of the bicycle development. With the incitation to the displacement on foot and the public transportation, it is a good and efficient way of environmental quality. For each case, the following points are presented: global policy of the local government, technical aspects and organization, economic, environmental aspects and behavior, future orientations and contacts. (A.L.B.)

  6. Estudio de viabilidad de cajones marítimos con hormigón con fibras

    OpenAIRE

    Ramos Marquès, Òscar Gonçal

    2017-01-01

    En este TFM se estudia la viabilidad de sustituir la armadura pasiva por fibras metálicas o plásticas en cajones para obras portuarias. Para ello, en primer lugar, se estudia el procedimiento constructivo de un cajón y las propiedades de los hormigones con fibras. Una vez analizado el estado del conocimiento se procede a escoger un cajón representativo, ya construido con armadura pasiva. El cajón escogido es el cajón tipo 3 del dique est...

  7. Pulpotomía con electrocauterio en pacientes con hemofilia A

    OpenAIRE

    Carbonell Rodriguez, Rosario

    2017-01-01

    Rehabilita la salud oral de un niños con Hemofilia A, empleando el Electrocauterio como una alternativa en la terapia pulpar, específicamente en la pulpotomía, para lo cual se realiza un minucioso examen clínico y anamnesis, que respaldados con exámenes complementarios, permite determinar el plan de tratamiento. La rehabilitación integral se llevó a cabo, previo consentimiento informado del padre, en sala de operaciones bajo anestesia general, debido a la condición sistémica del niño. Incl...

  8. SATISFACCIÓN CON EL TRATAMIENTO EN PACIENTES DE ATENCIÓN PRIMARIA CON ARTROSIS

    Directory of Open Access Journals (Sweden)

    Carmen Llanos Val Jiménez

    2017-01-01

    Full Text Available Fundamentos: Al igual que en otros problemas crónicos, en el abor - daje del paciente con artrosis se tiende a un modelo de toma de decisiones compartidas, en el que el punto de vista del paciente debe ser considerado en la elección del tratamiento. El objetivo de este trabajo fue evaluar la sa - tisfacción con el tratamiento en pacientes diagnosticados de osteoartrosis y comprobar si existen diferencias entre diferentes opciones farmacológicas, así como determinar si existe asociación con el estado funcional y las carac - terísticas clínicas y sociodemográficas. Métodos: Se realizó un estudio observacional transversal en una muestra de 487 pacientes seleccionados mediante muestreo consecutivo. La variable principal fue el nivel de satisfacción con el tratamiento (cuestionario ARTS. El estado funcional de los pacientes fue evaluado mediante la escala WO - MAC. Otras variables fueron: características del tratamiento, adherencia te - rapéutica, eventos adversos, y variables clínicas y sociodemográficas. Resultados: En el cuestionario ARTS los pacientes, en un rango entre 28 y 87, obtuvieron una puntuación media de 65,3 (DE: 9,9. La puntuación no fue significativamente diferente en consumidores de 1, 2 o más fármacos. Entre quienes consumían un solo fármaco, no hubo diferencias entre los di - ferentes tipos de fármacos. En el estado funcional se obtuvo una puntuación media de 30,2 puntos (DE: 20,8 y se observó una débil correlación negativa con el nivel de satisfacción (r= - 0,252; p<0,001. Mediante regresión lineal múltiple, se observó mayor puntuación en la escala ARTS (p<0,05 en pa - cientes con menor puntuación en la escala WOMAC, mayor edad y ausencia de eventos adversos. Conclusión : En pacientes con osteoartritis se observa un nivel mode - rado de satisfacción con el tratamiento farmacológico, condicionado por su situación funcional, sus características sociodemográficas y por la presencia de eventos

  9. Síndrome disejecutivo en personas con dependencia alcohólica con/sin recidivas

    OpenAIRE

    Fidalgo Martínez, Eva

    2015-01-01

    [ES]En la mayoría de las culturas el alcohol es el depresor del SNC utilizado con más frecuencia y el responsable de una morbilidad y una mortalidad considerables. En la actualidad, el consumo de bebidas alcohólicas constituye un importante problema de salud pública, especialmente en España, que es uno de los países con mayor consumo de alcohol por habitante y año. El objetivo general del estudio es determinar la existencia de diferencias significativas entre dos grupos clínicos de sujetos...

  10. Intervención con menores con adicciones desde Proyecto Hombre

    OpenAIRE

    Pardo-Esteban, Belén; Escalza-González, Amaia

    2015-01-01

    En el citado seminario informaremos del programa de atención y prevención de las toxicomanías y otras adicciones, llevado a cabo por la Asociación Proyecto hombre. A continuación, trataremos la formación en adicciones y toxicomanía con los estudiantes, mediante charla, cuestionarios sobre conocimientos básicos en prevención de toxicomanía en menores y los diferentes programas de intervención posibles aducados a los perfiles de los usuarios. Terminaremos con un debate sobre los temas tra...

  11. Terapéutica holística en una paciente con gingivitis descamativa crónica

    OpenAIRE

    Oliveros Noriega-Roldán, Silvana; Ortiz Moncada, Clara; Pérez Martínez, Manuel Antonio; Castellanos Ortiz, Betania; Cobián Mena, Alberto Erconvaldo

    2015-01-01

    Se describe el caso clínico de una paciente con gingivitis descamativa crónica, atendida en el Departamento de Periodoncia de la Clínica Estomatológica Provincial Docente "Mártires del Moncada" de Santiago de Cuba, en quien el tratamiento convencional no proporcionó resultados favorables, por lo cual se recurrió a la combinación de las terapias neural, acupuntural y periodontal y la aplicación de hipnosis, cuya combinación solucionó tan grave proceso inflamatorio, además de elevar la autoesti...

  12. Programa de Acompañamiento Psicosocial como intervención sociocomunitaria con familias en extrema pobreza en Chile

    OpenAIRE

    Oyarzún, D.; Dauvin, C.

    2016-01-01

    En Chile el abordaje de la pobreza centra sus bases en la Estrategia de Intervención Integral a favor de Familias en Extrema Pobreza y se consolida con la Ley 20379 que crea el Sistema Intersectorial de Protección Social, siendo la familia visualizada como sujeto potencial de las políticas sociales. El Programa de Acompañamiento Psicosocial, forma parte del Sistema Intersectorial de Protección Social, y es una intervención sociocomunitaria que busca promover en las familias el desarrollo de s...

  13. Uranium favorability of tertiary sedimentary rocks of the western Okanogan highlands and of the upper Columbia River valley, Washington

    International Nuclear Information System (INIS)

    Marjaniemi, D.K.; Robins, J.W.

    1975-08-01

    Tertiary sedimentary rocks in the northern portions of the western Okanogan highlands and in the upper Columbia River valley were investigated during a regional study to determine the favorability for potential uranium resources of the Tertiary sedimentary rocks of northeastern Washington. This project involved measurement and sampling of surface sections, collection of samples from isolated outcrops, and chemical and mineralogical analyses of samples. No portion of the project area of this report is rated of high or of medium favorability for potential uranium resources. Low favorability ratings are given to Oroville, Tonasket, and Pine Creek areas of the Okanogan River valley; to the Republic graben; and to the William Lakes, Colville, and Sheep Creek areas of the upper Columbia River valley. All these areas contain some fluvial, poorly sorted feldspathic or arkosic sandstones and conglomerates. These rocks are characterized by very low permeability and a consistently high siliceous matrix suggesting very low initial permeability. There are no known uranium deposits in any of these areas, and low level uranium anomalies are rare

  14. Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans

    Science.gov (United States)

    Sachse, Kathleen T; Jackson, Edwin K; Wisniewski, Stephen R; Gillespie, Delbert G; Puccio, Ava M; Clark, Robert SB; Dixon, C Edward; Kochanek, Patrick M

    2013-01-01

    Caffeine, the most widely consumed psychoactive drug and a weak adenosine receptor antagonist, can be neuroprotective or neurotoxic depending on the experimental model or neurologic disorder. However, its contribution to pathophysiology and outcome in traumatic brain injury (TBI) in humans is undefined. We assessed serial cerebrospinal fluid (CSF) concentrations of caffeine and its metabolites (theobromine, paraxanthine, and theophylline) by high-pressure liquid chromatography/ultraviolet in 97 ventricular CSF samples from an established bank, from 30 adults with severe TBI. We prospectively selected a threshold caffeine level of ≥1 μmol/L (194 ng/mL) as clinically significant. Demographics, Glasgow Coma Scale (GCS) score, admission blood alcohol level, and 6-month dichotomized Glasgow Outcome Scale (GOS) score were assessed. Mean time from injury to initial CSF sampling was 10.77±3.13 h. On initial sampling, caffeine was detected in 24 of 30 patients, and the threshold was achieved in 9 patients. Favorable GOS was seen more often in patients with CSF caffeine concentration ≥ versus theobromine and paraxanthine were also associated with favorable outcome (P = 0.018 and 0.056, respectively). Caffeine and its metabolites are commonly detected in CSF in patients with severe TBI and in an exploratory assessment are associated with favorable outcome. We speculate that caffeine may be neuroprotective by long-term upregulation of adenosine A1 receptors or acute inhibition of A2a receptors. PMID:17684518

  15. The effect of "in favor of myself": preventive program to enhance positive self and body image among adolescents.

    Science.gov (United States)

    Golan, Moria; Hagay, Noaa; Tamir, Snait

    2013-01-01

    Positive self-esteem, emotional well-being, school achievements and family connectedness are considered protective factors against health-compromising behaviors. This study examined the effect of an interactive, community-based, media literacy and dissonance wellness program, In Favor of Myself, on the self-image, body image, eating attitudes and behavior of young adolescents. A preliminary cohort study was conducted among 972 program participants who did not take part in the controlled trial. Over 75% of participants said they would recommend the program to their friends. A controlled trial was conducted to evaluate program acceptability, efficacy and effectiveness among 259 participants (210 in the intervention group and 49 in the control group), aged 12-14 years, who completed questionnaires during at least two assessment times. Program materials were provided, along with leaders' training, in order to ensure quality program delivery and creation of a wide network of committed program leaders. The program significantly reduced drive for thinness and self-worth contingent upon others' approval, the gap between current body figure and ideal figure, and the impact of mood on girls' self-image. Superiority was found among those participating in the intervention group with respect to recognizing media strategies, the influence of media on desire to change, and the influence of appearance on self-confidence and drive for thinness. In Favor of Myself shows promising results for strengthening adolescents' ability to cope with the challenges of their life stage. Suggestions for improving In Favor of Myself are presented.

  16. ¿Quién se opone a la prevención?: Un mapa de los actores pro tabaco en España Who is against prevention?: A map of policy actors favoring smoking in Spain

    Directory of Open Access Journals (Sweden)

    Lluís Granero

    2004-10-01

    Full Text Available Objetivos: Para poder realizar un abordaje integral de las políticas referidas al tabaquismo hay que conocer el mapa de los actores relacionados con el tabaco y sus vínculos políticos. En este trabajo se pretende presentar una primera aproximación en España. Métodos: Análisis de la prensa, publicaciones de la industria y entrevistas con personas clave. Se identifican los actores pro tabaco activos en España, que se han podido clasificar según su naturaleza, la esfera en que se mueven y su ámbito territorial preferente. Resultados: Se identifican las empresas tabaqueras, entre las que destacan Altadis y Philip Morris por su dominio del mercado, las organizaciones del comercio minorista (estanqueros, las organizaciones «pantalla» creadas por la industria (Club de Fumadores por la Tolerancia, las de cultivadores y las empresas de transformación. La distribución está dominada por Logista, filial de Altadis. Hay que tener en cuenta también las empresas de vending y de productos complementarios (mecheros, fósforos y papel. Se identifican los vínculos de estos actores con la Administración pública, donde destaca el papel que desempeña el Comisionado para el Mercado de Tabacos, así como los Ministerios de Agricultura, Hacienda y Economía. Se identifican también las relaciones con la patronal, algunos partidos políticos y sindicatos, así como con otros sectores empresariales con gran influencia social, como los medios de comunicación y la publicidad. Conclusiones: El mapa de los actores pro tabaco en España es complejo y supera los límites de la estricta industria tabaquera. La comprensión de este entramado es fundamental para poder plantear políticas integrales de prevención.Objectives: For a comprehensive approach to policies on smoking, the map of actors related to tobacco and their political ties needs to be identified. The present article constitutes the first attempt at this task in Spain. Methodology: Analysis of

  17. Experimentos en Antioquia con Fertilizantes para Papa.

    Directory of Open Access Journals (Sweden)

    Yepes Y. Emilio

    1949-03-01

    Full Text Available Con el fin de determinar la adecuada aplicación de cal. y la economía de la adición de Nitrógeno, Fósforo y Potasio, se realizaron varios experimentos de fertilizantes para papa en dos regiones productoras de Antioquia. Los experimentos se realizaron por el sistema de "Parcelas divididas y del análisis estadístico de los resultados pueden sacarse las siguientes conclusiones: 1. Es notable la deficiencia de Fósforo en ambos suelos, y hubo respuesta significativa a una aplicación de 120 kilos por hectárea. 2. Los suelos responden a una aplicación moderada de Nitrógeno y Potasio, pero puede lograrse una economía importante en las cantidades de estos elementos. 3. Parece que la aplicación de dos toneladas de cal por cuadra es suficiente, y no hay razón para aconsejar cantidades mayores. 4. Los resultados obtenidos demuestran que sí es posible la experimentación con fertilizante para papa, y sería de desear que se ampliara la experimentación en las demás regiones productoras.

  18. Polimiositis con incapacidad ventilatoria e insuficiencia respiratoria

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    O. Lopez Gaston

    2003-10-01

    Full Text Available Las miopatías inflamatorias son un grupo de enfermedades caracterizadas por debilidad muscular proximal y las causas mayores incluyen la polimiositis (PM, dermatomiositis y miositis por cuerpos de inclusión. Las complicaciones respiratorias son comunes y adquieren importancia por la incidencia sobre el pronóstico. Las tres formas de compromiso frecuentes son la enfermedad pulmonar intersticial, la neumopatía aspirativa y la incapacidad ventilatoria (IV por debilidad de los músculos respiratorios, que en su forma severa es de ocurrencia excepcional. Se presenta una paciente con IV sin compromiso del parénquima pulmonar, que requirió asistencia respiratoria mecánica por 4 meses con «destete» exitoso.The inflammatory diseases of muscle are a group of disorders characterized by proximal muscle weakness. Most cases fall into three major diagnostic categories, polymyositis (PM, dermatomyositis and inclusion body myositis. Respiratory complications are a common feature and are an important cause of morbidity and mortality. The three main types of pulmonary involvement are interstitial lung disease, aspiration pneumonia and ventilatory incapacity (VI due to muscle weakness. There are few reported cases in which mechanical ventilation has been used in patients with PM and VI in absense of lung disease. We present a patient with PM and VI due to muscle weakness who underwent therapy maintenance with mechanical ventilator and was weaned 4 months later.

  19. Optimización con Solver

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    Sánchez Álvarez , I.

    1998-01-01

    Full Text Available La relevancia de los problemas de optimización en el mundo empresarial ha generado la introducción de herramientas de optimización cada vez más sofisticadas en las últimas versiones de las hojas de cálculo de utilización generalizada. Estas utilidades, conocidas habitualmente como «solvers», constituyen una alternativa a los programas especializados de optimización cuando no se trata de problemas de gran escala, presentado la ventaja de su facilidad de uso y de comunicación con el usuario final. Frontline Systems Inc es la empresa que desarrolla el «solver» de Excel, si bien existen asimismo versiones para Lotus y Quattro Pro con ligeras diferencias de uso. En su dirección de internet (www.frontsys.com se puede obtener información técnica sobre las diferentes versiones de dicha utilidad y diversos aspectos operativos del programa, algunos de los cuales se comentan en este trabajo.

  20. Plantas con actividad fotosensibilizadora y potencial terapéutico en leishmaniasis cutánea: hipericina, una alternativa prometedora

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    Viviana Milena Taylor O

    Full Text Available La leishmaniasis es una enfermedad endémica en 98 países, con más de 350 millones de personas en riesgo de adquirir la infección y 12 millones de personas infectadas. Numerosas desventajas asociadas a los tratamientos actuales promueven la falta de adherencia o abandono del tratamiento y la aparición de cepas resistentes al medicamento. Estos factores han estimulado la búsqueda de alternativas terapéuticas que sean rápidas, seguras, de fácil administración y económicas. Surge así la etnobotánica, que en combinación con la fototerapia puede convertirse en una estrategia innovadora para la búsqueda de compuestos de origen natural con actividad leishmanicida, donde productos como la hipericina pueden ser considerados candidatos prometedores en el descubrimiento y desarrollo de nuevos tratamientos. La hipericina es una molécula de origen natural que presenta un rendimiento cuántico alto en su estado triplete y genera eficientemente especies reactivas de oxígeno, lo cual posiblemente la hace un buen agente leishmanicida al ser aplicado en los tejidos infectados, además de ser posiblemente un potencial agente cicatrizante, que otorga un efecto cosmético favorable en la resolución de la lesión, con amplias ventajas como bajo costo y fácil manejo, convirtiéndose en una alternativa favorable frente a otras usadas en el manejo de la enfermedad.

  1. Efecto del medio y condiciones de cultivo en la productividad de tres diatomeas marinas con potencial acuícola

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    Martha J. Prieto

    2005-05-01

    Full Text Available Las diatomeas Actinocyclus normanii , Cyclotella gromerata y Neodelphyneis pelagica fueron trabajadas en ellaboratorio de Alimento Vivo de la Universidad de Córdoba, con el fin de caracterizar las especies, obtenercepas y realizar cultivos experimentales bajo condiciones controladas de temperatura (24oC, salinidad (25-300/00 y aireación. Cultivos a 5 ml y 250 ml fueron realizados con dos medios de cultivo como tratamiento (F/2 deGuillar & Rither, y CONWAY para determinar su efecto sobre la productividad. Mediante observaciones periódicas(cada 6 horas, se registró el tamaño y densidad celular, así como, la tasa de crecimiento (K. Los resultadosmostraron diferencia significativa para el efecto de los medios de cultivo sobre el crecimiento poblacional de lasmicroalgas, las cuales alcanzan concentraciones de 267214,1 ± 277,77 cel.ml-1; 1606117 ± 69686,7 cel.ml-1 y 2735703 ± 49180,8 cel.ml-1 respectivamente para cada especie. Se concluyó que estas microalgas por suscaracterísticas de crecimiento en cultivo, presentan adaptación favorable a las condiciones de manejo para laproducción de biomasas frescas con “F/2” siendo este el medio mas adecuado, asimismo, por su tamaño sonpotencialmente útiles para ser empleadas como partícula nutritiva con fines acuícolas.

  2. Nefropatía membranosa secundaria a exposición laboral con mercurio metálico

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    Ana Voitzuk

    2014-10-01

    Full Text Available Las nefropatías tóxicas secundarias a la exposición ocupacional a metales han sido ampliamente estudiadas. La nefropatía membranosa por mercurio es poco frecuente.La intoxicación ocupacional con mercurio sí es frecuente, siendo las principales formas de presentación las manifestaciones clínicas neurológicas. La afectación renal secundaria a la exposición crónica a mercurio metálico puede desarrollar enfermedad glomerular por depósito de inmunocomplejos. La glomerulopatía membranosa y a cambios mínimos son las más frecuentemente comunicadas.Se presenta el caso de un paciente con exposición ocupacional a mercurio metálico, con síndrome nefrótico y biopsia renal con glomerulopatía membranosa que presentó respuesta favorable luego del tratamiento quelante e inmunosupresor.

  3. Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer

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    Vinayak Muralidhar

    2016-02-01

    Full Text Available Purpose : Recent retrospective data suggest that brachytherapy (BT boost may confer a cancer-specific survival benefit in radiation-managed high-risk prostate cancer. We sought to determine whether this survival benefit would extend to the recently defined favorable high-risk subgroup of prostate cancer patients (T1c, Gleason 4 + 4 = 8, PSA 20 ng/ml. Material and methods: We identified 45,078 patients in the Surveillance, Epidemiology, and End Results database with cT1c-T3aN0M0 intermediate- to high-risk prostate cancer diagnosed 2004-2011 treated with external beam radiation therapy (EBRT only or EBRT plus BT. We used multivariable competing risks regression to determine differences in the rate of prostate cancer-specific mortality (PCSM after EBRT + BT or EBRT alone in patients with intermediate-risk, favorable high-risk, or other high-risk disease after adjusting for demographic and clinical factors. Results : EBRT + BT was not associated with an improvement in 5-year PCSM compared to EBRT alone among patients with favorable high-risk disease (1.6% vs. 1.8%; adjusted hazard ratio [AHR]: 0.56; 95% confidence interval [CI]: 0.21-1.52, p = 0.258, and intermediate-risk disease (0.8% vs. 1.0%, AHR: 0.83, 95% CI: 0.59-1.16, p = 0.270. Others with high-risk disease had significantly lower 5-year PCSM when treated with EBRT + BT compared with EBRT alone (3.9% vs. 5.3%; AHR: 0.73; 95% CI: 0.55-0.95; p = 0.022. Conclusions : Brachytherapy boost is associated with a decreased rate of PCSM in some men with high-risk prostate cancer but not among patients with favorable high-risk disease. Our results suggest that the recently-defined “favorable high-risk” category may be used to personalize therapy for men with high-risk disease.

  4. con enfermedad crónica

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    María del Refugio Zavala Rodríguez

    2007-01-01

    Full Text Available El propósito del estudio fue determinar el grado de correlación entre los niveles de fortaleza para la salud y de ansiedad-rasgo, en unamuestra de 200 pacientes integrada por medio de muestreo no probabilístico; los criterios de inclusión fueron: adultos de ambos génerosdiagnosticados con enfermedad crónica, con estudios de enseñanza básica y orientada. El marco teórico que guió la investigación es elModelo de Adaptación de Roy. El diseño fue descriptivo, transversal, correlacional. Se utilizó el cuestionario de fortaleza de S. Pollock y laescala de autoevaluación de ansiedad-rasgo de Spielberger; los instrumentos presentaron una consistencia interna aceptable con unAlpha de Cronbach de ,852 y ,813 respectivamente. La información se recabó de cuatro instituciones de salud ubicadas en los municipiosde Tampico-Cd. Madero Tamaulipas, México. El análisis de los datos se efectuó mediante estadística descriptiva e inferencial, se utilizó elpaquete estadístico SPSS versión 13. El rango de edad que predominó fue de 45 a 64 años (54%; el 55% fue del sexo femenino, el 48%cuenta con estudios de primaria, cerca del 90% padece de una enfermedad metabólica. El coeficiente de correlación de Spearman entrela fortaleza para la salud y la ansiedad-rasgo fue significativo (Œ,570, valor Œp,000. En la mayoría de la población participante se encontróun nivel moderado tanto de fortaleza (83% como de ansiedad (73%. El análisis de regresión múltiple indicó que la relación significativaentre estas dos variables no es afectada por la edad, el género o los años de evolución de la enfermedad crónica. Los datos de este estudiomuestran evidencia de que en los pacientes con enfermedades crónicas a mayor nivel de fortaleza menor nivel de ansiedad-rasgo. Estasituación invita a desarrollar más estudios de estos fenómenos, en la disciplina de enfermería, que sirvan como sustento teórico-prácticopara el diseño o la mejora de

  5. Estrategias de ventilación a favor de la neuroprotección: ¿qué podemos hacer?

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    G. Cordero González

    2016-07-01

    Full Text Available Gracias al perfeccionamiento de las técnicas de atención prenatal y perinatal se ha logrado una mayor sobrevida de pacientes prematuros con edades gestacionales cada vez menores; su grado de inmadurez los hace susceptibles al desarrollo de enfermedades en los diferentes aparatos y sistemas, comorbilidades que merman su crecimiento y desarrollo afectando su calidad de vida a corto, mediano y largo plazo. El cerebro, al ser un órgano de gran importancia por estar relacionado con la funcionalidad integral del individuo, no se escapa, y las complicaciones que lo afectan pueden ser transitorias o permanentes, e incluyen una amplia gama de manifestaciones clínicas que van desde un retraso en el neurodesarrollo hasta parálisis cerebral. Es por eso que debemos preocuparnos por la prevención de las mismas con mejoras en la atención prenatal y neonatal que incluyan estrategias de ventilación gentiles, adecuada nutrición, terapias farmacológicas, maniobras de estimulación temprana, rehabilitación oportuna de los pacientes y el seguimiento a largo plazo, pues las alteraciones en el neurodesarrollo pueden afectar hasta una tercera parte de los pacientes prematuros.

  6. Reducción de color con cloruro de magnesio en soluciones con colorantes comerciales

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    Mercedes Lucero Chávez

    2017-01-01

    Full Text Available Se experimentó con diferentes concentraciones de cloruro de magnesio (MgCl2 como coagulante para reducir el color en soluciones con colorantes comerciales: negro, azul y café. Los parámetros analizados fueron pH, color, demanda química de oxígeno ( dqo y sólidos suspendidos totales (sst de acuerdo con las Normas Mexicanas. Como prueba complementaria se agregó carbón activado a las muestras para reducir el color residual después de la coagulación-floculación. La reducción de los valores de color y dqo fue mayor cuando se adicionó más cantidad de MgCl2 (1.8 g/L. Los porcentajes de reducción fueron ≥90% para el color y >50% para la dqo. Los sst aumentaron con la adición de MgCl2. El carbón activado eliminó el color residual.

  7. Queratitis ulcerativa periférica bilateral en paciente con artritis reumatoide: tratamiento con infliximab

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    Vicente Aldasoro-Cáceres

    2017-01-01

    Discusión: La PUK es una enfermedad rara, pero a tener en cuenta en los pacientes con AR. En la mayoría de los casos, el tratamiento de fondo debe ser intensificado; en este sentido deben considerarse los tratamientos biológicos por su eficacia y efecto rápido de acción.

  8. ESTUDIO DE LA DIGESTION HUMANA CON ALUMNOS CON DIFICULTADES DE APRENDIZAJE

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    Mª Begoña Carretero Gómez

    2009-01-01

    Full Text Available En esta experiencia se han seleccionado una serie de actividades relacionadas con la digestión con el fin de lograr una reestructuración de ideas y cambios conceptuales, y así con la conseguir que el alumnado aprenda a construir sus propios conocimientos acerca de cómo y donde se dan los procesos de digestión necesarios para la nutrición del organismo. El trabajo se ha llevado a cabo con alumnos de 3º de Educación Secundaria Obligatoria, pertenecientesal programa de diversificación curricular. Hemos querido hacer la ciencia más cercana para que comprendan que algunos procesos tienen su explicación científica y que la ciencia forma parte de nuestro día a día, fomentando el interés del estudiante así como su implicación en el proceso de enseñanza-aprendizaje. Por ello hemos trabajado a base de pequeñas investigaciones, donde es el alumno el que marca su ritmo de trabajo, investiga y hace sus aportaciones. Han aprendido a trabajar de una forma meticulosa donde el rigor esfundamental, contagiándose del afán investigador de manera que al realizar las experiencias se han aproximado al trabajo científico a la vez que aclaran y reestructuran conocimientos.

  9. FORTIFICACIÓN DE PULPA DE UCHUVA CON CALCIO, OLIGOFRUCTOSA Y VITAMINA C, ESTABILIZADA CON HIDROCOLOIDE

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    ALBA LUCIA DUQUE

    2014-06-01

    Full Text Available La pulpa de uchuva fortificada con calcio, oligofructosa y vitamina C es un alimento funcional con grandes beneficios para la salud. Para ello se le adicionó componentes biológicamente activos, como ácidos grasos, fibra alimentaria y antioxidantes. En este trabajo se estudió la estabilidad de la pulpa enriquecida en diferentes formulaciones, teniendo en cuenta los criterios de incorporación de calcio y vitamina C (20% del valor diario recomendado VDR y para la oligofructosa (fibra dietaría en relación 1:1 con el calcio. Los resultados obtenidos mostraron que la pulpa de uchuva fortificada con CMC, ologofructosa, calcio y vitamina C presentó en promedio una estabilidad de 87,7±10,0; una viscosidad de 22,8±7,9; una aw de 0,9863±0; pH de 3,3±0,1; acidez de 1,6±0,1; grados Brix de 13,3±0,7; una densidad de 1,32±0 g/mL y las mejores respuestas sensoriales en cuanto a color, aroma, fluidez y sabor.

  10. Terapia regenerativa con plasma rico en plaquetas en pacientes con quemaduras

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    María del Carmen Franco Mora

    2015-10-01

    Full Text Available Se realizó un estudio comparativo, longitudinal y prospectivo de 60 adultos con quemaduras profundas, atendidos en el Hospital General docente "Dr. Juan Bruno Zayas Alfonso" de Santiago de Cuba, desde febrero de 2013 hasta igual mes de 2014, para evaluar la efectividad de la terapia regenerativa con plasma rico en plaquetas para la cicatrización de estas lesiones. La muestra fue dividida en 2 grupos de 30 integrantes cada uno: a los del primero se les aplicó plasma rico en plaquetas y a los del segundo sulfadiazina de plata. Se utilizaron las frecuencias absolutas y el porcentaje como medidas de resumen para variables cualitativos, así como la media aritmética y la desviación estándar para las cuantitativas. Con el proceder aplicado la cicatrización se completó en un tiempo menor, de manera que se demostró la efectividad de esta alternativa terapéutica en relación con el tratamiento convencional

  11. Efectos del contacto piel con piel del recién nacido con su madre

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    Camila Lucchini Raies

    Full Text Available Antecedentes: el contacto piel con piel ha sido una práctica ancestral en toda cultura, que debido a la institucionalización de la atención del parto, disminuyó en occidente. Se retomó en el marco de la atención humanizada del parto. Objetivo principal: determinar los efectos del contacto piel con piel del recién nacido con su madre. Metodología: revisión bibliográfica de 26 estudios. Límites de búsqueda: new borns, humans, clinical trials, de 10 años de publicación, en bases de datos: Pubmed, ProQuest, CINHAL, Lilacs. Resultados principales: Se observaron beneficios en las variables: duración de lactancia materna, comportamiento neurosensorial, regulación de temperatura, como alternativa al cuidado estándar, disminución en días hospitalización y niveles de cortisol, favorecedor de la interacción madre-hijo y desarrollo infantil. Conclusión principal: el contacto piel con piel brinda múltiples beneficios a recién nacidos. Se presenta como alternativa de cuidado segura, factible de implementar.

  12. Estudio observacional prospectivo con insulina detemir en pacientes con diabetes mellitus tipo 2 mal controlados que inician por primer vez tratamiento con insulina (estudio SOLVE

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    Domingo Orozco-Beltrán

    2016-02-01

    Conclusiones: En esta cohorte de pacientes con diabetes mellitus tipo 2 recientemente insulinizados, la insulina detemir (una vez al día mejoró el control glucémico, con baja incidencia de hipoglucemia y una reducción significativa del peso.

  13. BIOMASA Y RENDIMIENTO DE FRIJOL CON POTENCIAL EJOTERO EN UNICULTIVO Y ASOCIADO CON GIRASOL

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    J. Garduño-González

    2009-01-01

    Full Text Available El objetivo del presente estudio fue estimar la producción de biomasa, rendimiento y algunos de sus componentes de dos cultivares de frijol (Phaseolus vulgaris L. con potencial ejotero ('Acerado' y 'Criollo', en unicultivo y asociado con dos cultivares de girasol (Helianthus annuus L. ('Sunbright' y 'Victoria'. El estudio se realizó durante el ciclo primavera verano 2006 bajo condiciones de temporal en Tenancingo, Méx. Las variables evaluadas fueron: índice de área foliar (IAF, tasa de asimilación neta (TAN, biomasa total (BT, diámetro de vaina (DV, longitud de vaina (LV, número de vainas·m-2 (NV y rendimiento de vaina·m-2 (RV; las cuales fueron analizadas en arreglo factorial, bajo un diseño de bloques completos al azar con cuatro repeticiones. Para estimar el grado de asociación, entre las variables estudiadas y el rendimiento de vainas, se realizó un análisis de correlación lineal simple. En el factor cultivares se detectaron diferencias estadísticas significativas para la TAN y DV; para el factor sistemas de siembra hubo diferencias significativas para BT, DV, NV y RV. La interacción cultivares * sistema de siembra fue significativa en todas las variables, excepto en la TAN. En ese sentido, las asociaciones 'Criollo' + 'Sunbright', 'Acerado' + 'Victoria' y 'Acerado' en unicultivo, presentaron el mayor RV. Las variables IAF, BT y NV se correlacionaron positiva y significativamente con el rendimiento de vaina. Los resultados indican que 'Criollo' y 'Acerado', asociados con 'Sunbright' y 'Victoria', respectivamente, responden positivamente a la asociación, constituyendo una buena opción para los productores de la región de Tenancingo, México.

  14. Incidencia y factores asociados con las reacciones adversas del tratamiento antirretroviral inicial en pacientes con VIH

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    Juan Astuvilca

    2007-07-01

    Full Text Available La alta incidencia de reacciones adversas medicamentosas (RAMA al tratamiento antirretroviral de gran actividad (TARGA en pacientes con VIH/SIDA puede afectar la calidad de vida y adherencia al tratamiento. Objetivos: Determinar la incidencia de RAMA del TARGA inicial e identificar los factores asociados con la ocurrencia de RAMA al recibir dicha terapia. Materiales y métodos: Se realizó un estudio de cohorte histórica con todos los pacientes VIH (+ mayores de 18 años que recibieron TARGA por primera vez en el Hospital Nacional Arzobispo Loayza, con un seguimiento de 360 días desde la primera prescripción. Se recabó las RAMA de las historias clínicas y tarjetas de control. Resultados: Se incluyeron 353 pacientes, se encontró una incidencia acumulada de 66,7% de efectos adversos al TARGA inicial y una densidad de incidencia de 9,1 eventos de RAMA por 10 personas año de seguimiento (IC95%: 8,1-10,1. Anemia (23,4%, náuseas (20,6% y rash (17,2% fueron las RAMA más frecuentes. El uso de drogas (OR 2,40; IC95% 1,01-5,67; consumo de alcohol (OR 0.32; IC95%: 0,19-0,55 y estadio SIDA (OR 0,20; IC95%: 0,04-0,95 estuvieron asociadas con la presencia de RAMA. Conclusiones: Existe un alta incidencia de RAMA, siendo la anemia la más frecuente. El uso de drogas es un factor de riesgo para presentar RAMA.

  15. Hidroxilación de fenol con catalizadores ZSM-5 modificado con cobre

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    César Augusto Caro

    2005-01-01

    Full Text Available Se sintetizaron varios catalizadores Cu-ZSM-5 con diferentes relaciones Si/Al y Si/Cu. Usando metilamina o hidróxido de sodio como agente mineralizante. Los catalizadores se caracterizaron por DRX, IR, análisis BET, UV-VIS y análisis elemental. El desempeño catalítico de los catalizadores sintetizados se evaluó en la hidroxilación de fenol con H2O2. Se encontró que la relación catecol (CAT/(hidroquinona (HQ + p-benzoquinona (PBQ aumentó con el contenido de agua, presentó un máximo cuando la relación en peso de agua/fenol fue de 53/1 y se favoreció a altas temperaturas, con el aumento del contenido de aluminio o con la disminución en el contenido de catalizador. El contenido de cobre no fue un factor determinante para la conversión ni para la selectividad en la hidroxilación de fenol. La producción de la p-benzoquinona (PBQ, producto de oxidación de la hidroquinona, fue mínimo cuando se usaron las siguientes condiciones: 80 ºC, fenol: 1 mmol, relación molar fenol/H2O2 de 3/1, catalizador: 20 mg, agua: 5 g, tiempo de reacción: 4 h.

  16. Efectos del contacto piel con piel del recién nacido con su madre Skin to skin contact effects in newborns and their mothers

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    Camila Lucchini Raies

    2012-12-01

    Full Text Available Antecedentes: el contacto piel con piel ha sido una práctica ancestral en toda cultura, que debido a la institucionalización de la atención del parto, disminuyó en occidente. Se retomó en el marco de la atención humanizada del parto. Objetivo principal: determinar los efectos del contacto piel con piel del recién nacido con su madre. Metodología: revisión bibliográfica de 26 estudios. Límites de búsqueda: new borns, humans, clinical trials, de 10 años de publicación, en bases de datos: Pubmed, ProQuest, CINHAL, Lilacs. Resultados principales: Se observaron beneficios en las variables: duración de lactancia materna, comportamiento neurosensorial, regulación de temperatura, como alternativa al cuidado estándar, disminución en días hospitalización y niveles de cortisol, favorecedor de la interacción madre-hijo y desarrollo infantil. Conclusión principal: el contacto piel con piel brinda múltiples beneficios a recién nacidos. Se presenta como alternativa de cuidado segura, factible de implementar.Background: skin to skin contact has been an ancient practice in all cultures, that due to the institutionalization of care delivery, decreased in the west. Was revived as part of humanized care delivery. Main objective: to determine effects of skin contact of the newborn with her mother. Methodology: a review of 26 studies. Search limits: new borns, Humans, clinical trials, 10 years of publication, database PubMed, ProQuest, CINAHL, Lilacs. Main results: benefits were seen in the following variables: duration of breastfeeding, neurosensorial behavior, temperature regulation, as an alternative to standard care, decreased of hospitalization days and cortisol levels, favoring the mother-child interaction and child development. Main conclusion: skin to skin contact provides multiple benefits to newborns. It is presented as an alternative to secure care, feasible to implement.

  17. Los profesores de alumnos con altas habilidades

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    Cándido GENOVARD

    2010-01-01

    Full Text Available En este trabajo analizamos las características de los profesores expertos para alumnos de altas habilidades. Se analizan los antecedentes del tema y el proceso instruccional para atender la diversidad de estos alumnos. Se destaca el valor de las interacciones entre profesor¿ alumnos y los estilos de enseñar y aprender. Asimismo, recogemos pautas de acción y recursos instruccionales a utilizar en el aula para la enseñanza de estos alumnos. No hay un profesor ideal para los alumnos con altas habilidades, pero los docentes deben conocer qué son y cómo funcionan los procesos de enseñanza¿aprendizaje y las variables psicológicas, de contenidos y contextuales implicadas en éstos.

  18. Cenizas, cementos y hormigones con cenizas

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    Calleja, José

    1982-09-01

    Full Text Available This paper describes the chemical composition and the morfological nature of pulverized coal ashes, as well as their physical characteristics. Their influences —actions and effects— on the main properties and behaviour of cements and concretes, and the more adequate conditions for their efficient use un them are also described.

    En este trabajo se exponen la composición química y la naturaleza morfológica de las cenizas pulverulentas de los carbones, así como sus características físicas. Se describen asimismo sus influencias —acciones y efectos— sobre las principales propiedades y comportamientos más importantes de los cementos y de los hormigones, así como las condiciones más idóneas para su más eficaz empleo con y en ellos.

  19. Estudio de pacientes colombianos con homocistinuria

    Directory of Open Access Journals (Sweden)

    M. Bermúdez

    2001-07-01

    Full Text Available La homocistinuria es una alteración bioquímica producida por causas genéticas como son la deficiencia de alguna de las enzimas involucradas en el metabolismo de metionina u homocisteína: Cistationina b sintasa, 5-10 Metilentetrahidrofolato reductasa, o Metionina sintasa al igual que a deficiencias nutricionales y asocio a otras patologías como son la enfermedad renal y problemas  vasculares. El objetivo de este trabajo es la identificación de la deficiencia bioquímica en pacientes con homocistinuria, mediante la cuantificación de las enzimas involucradas, utilizando como muestras fibroblastos y linfocitos.

  20. Cervical disc arthroplasty: Pros and cons.

    Science.gov (United States)

    Moatz, Bradley; Tortolani, P Justin

    2012-01-01

    Cervical disc arthroplasty has emerged as a promising potential alternative to anterior cervical discectomy and fusion (ACDF) in appropriately selected patients. Despite a history of excellent outcomes after ACDF, the question as to whether a fusion leads to adjacent segment degeneration remains unanswered. Numerous US investigational device exemption trials comparing cervical arthroplasty to fusion have been conducted to answer this question. This study reviews the current research regarding cervical athroplasty, and emphasizes both the pros and cons of arthroplasty as compared with ACDF. Early clinical outcomes show that cervical arthroplasty is as effective as the standard ACDF. However, this new technology is also associated with an expanding list of novel complications. Although there is no definitive evidence that cervical disc replacement reduces the incidence of adjacent segment degeneration, it does show other advantages; for example, faster return to work, and reduced need for postoperative bracing.

  1. RadCon Occurrence Reporting Simplified

    International Nuclear Information System (INIS)

    Denham, D. H.

    1999-01-01

    This narrative and accompanying diagrams provide a simplified summary of the RadCon Occurrence Reporting criteria to allow Environmental Restoration Contractor (ERC) staff to efficiently recognize occurrences and to effectively initiate the implementation of the requirements of U.S. Department of Energy (DOE) Order 232.1A, Occurrence Reporting and Processing of Operations Information, and of the ERC criteria defined in BHI-MA-02, ERC Project Procedures, Procedure 2.6, ''Occurrence Investigation and Reporting.'' These directives promote timely identification, categorization, notification, and reporting to DOE and ERC management of reportable occurrences at DOE-owned or -operated facilities that could (1) affect health and safety of the public, (2) seriously impact the intended purpose of DOE facilities, (3) adversely affect the credibility of DOE, or (4) have a noticeable adverse effect on the environment

  2. Con los ojos en las pieles

    Directory of Open Access Journals (Sweden)

    Andrés Inocente Martín Hernández

    2016-10-01

    Full Text Available Metáforas Construidas, exposición realizada en Bogotá, Colombia, donde se exhibieron obras de la artista brasileña Regina Silveira, seleccionadas a partir de una línea conceptual que relacionó el recorte cronológico de la producción de la artista en relación directa con el contexto arquitectónico del espacio expositivo. Esa relación direccional fue considerada en la inserción de los trabajos de otros cuatro artistas en la exposición. El texto destaca los diálogos y métodos utilizados para la concepción, construcción y discusión de la exposición.

  3. Accesibilidad digital para usuarios con limitaciones visuales

    Directory of Open Access Journals (Sweden)

    Toledo, Gabriela Alejandra

    2013-04-01

    Full Text Available El presente trabajo persigue como objetivos: recapitular y analizar los principios básicos de diseño para el desarrollo de tecnologías inclusivas; evaluar ventajas y desventajas en el uso del programa lector de pantalla (JAWS al acceder a entornos comunicacionales, desde las variables de navegabilidad, interoperabilidad, usabilidad y colaboración en la cognición; derivar sugerencias acerca del diseño de entornos de aprendizaje colaborativo, de modo de lograr una mayor efectividad de esta herramienta digital, aplicada a personas con limitaciones en la visión en diverso grado; redactar un manual complementario de orientaciones que facilite el uso de este instrumento inclusivo, aplicado a entornos de enseñanza/ aprendizaje colaborativo.

  4. Jícama: Producto con Identidad Territorial

    Directory of Open Access Journals (Sweden)

    Marisol Idrovo Avecillas

    2015-11-01

    La jícama es un producto con identidad territorial (PIT, son fragmentos de la perspectiva de tierras aptas para el cultivo, producción, comercialización sostenible que se apega al Plan Nacional del Buen Vivir, que se ajusta al cambio de la Matriz Productiva incluyendo a los sectores involucrados del país, este vegetal andino no es consumido regularmente por los ecuatorianos; los resultados obtenidos en el laboratorio nos indican que es un vegetal rico en: grasa, proteína, humedad, fibra dietética, carbohidratos totales, energía total, energía de la grasa, hierro, sodio, potasio, calcio, vitaminas, entre otras propiedades.

  5. The role of p53 in radiation therapy outcomes for favorable-to-intermediate-risk prostate cancer

    International Nuclear Information System (INIS)

    Ritter, Mark A.; Gilchrist, Kennedy W.; Voytovich, Marta; Chappell, Richard J.; Verhoven, Bret M.

    2002-01-01

    Purpose: Some prostate cancers may have molecular alterations that render them less responsive to radiation therapy; identification of these alterations before treatment might allow improved treatment optimization. This study investigated whether p53, a potential molecular determinant, could predict long-term radiation therapy outcome in a restricted group of relatively favorable-risk prostate cancer patients treated uniformly with irradiation alone. Methods and Materials: This study included 53 patients previously treated with radiotherapy for favorable-to-intermediate-risk prostate cancer. These patients were selected for relatively low pretreatment PSAs (≤21 ng/mL) and Gleason scores (≤7) to decrease the likelihood of nonlocalized disease, because disease localization was necessary to examine the efficacy of localized radiation therapy. The status of p53 was immunohistochemically assessed in paraffin-embedded pretreatment biopsy specimens, along with appropriate controls. This marker was selected based upon a usable mutation prevalence in early-stage prostate cancer and its potential linkage with radiation response via cell cycle, DNA repair, and cell death pathways. Correlation between p53 mutation and clinical outcome was analyzed in univariate and multivariate fashion and included conventional prognosticators, such as stage, grade, and PSA. Freedom from biochemical failure was determined using American Society for Therapeutic Radiology and Oncology criteria. Limitations of prior studies were potentially avoided by requiring adequate posttreatment follow-up (median follow-up in nonfailing patients of 5.1 years), as well as pretreatment PSA and Gleason scores that suggested localized disease, and uniformity of treatment. Results: The total group of 53 favorable-to-intermediate-risk patients demonstrated an actuarial biochemical failure rate of 35% at 5 years. Forty percent of all specimens had a greater than 10% labeling index for p53 mutation, and

  6. Lesiones bucales relacionadas con las enfermedades digestivas

    Directory of Open Access Journals (Sweden)

    José A. Pacho Saavedra

    2006-09-01

    Full Text Available Muchas de las lesiones de la mucosa en la cavidad bucal están relacionadas con trastornos anatómicos y funcionales de los órganos del aparato digestivo; algunas forman parte del cuadro clínico de la entidad y otras aparecen como complicaciones de estas. Generalmente son de orígenes inmunológicos, nutricionales o carenciales. Estas lesiones son difíciles de tratar, por lo que es importante conocer las características clínicas que faciliten una adecuada interpretación y al mismo tiempo ofrecer una conducta terapéutica correcta. Se presenta una revisión actualizada de las características semiológicas de las lesiones bucales que forman parte del cuadro clínico de diversas enfermedades digestivas, con el fin de que los médicos generales, clínicos, estomatólogos y gastroenterólogos puedan diagnosticarlas y brindar mejor orientación y tratamiento a los pacientes.Many of the lesions of the mucosa in the oral cavity are related to anatomical and functional disorders of the organs of the digestive system. Some of them are part of the clinical picture of the entity and others appear as complications of them. Generally, they have an immunological, nutritional, or deficiency origin. These lesions are difficult to be treated and that's why it is important to know the clinical characteristics making easy an adequate interpretation, and to follow a suitable therapeutic conduct at the same time. An updated review of the semiological features of the oral lesions corresponding to the clinical picture of diverse digestive diseases is presented, so that the general physicians, clinicians, stomatologists and gastroenterologists be able to diagnose and give a better guidance and treatment to the patients.

  7. Lumpectomy Plus Tamoxifen or Anastrozole With or Without Whole Breast Irradiation in Women With Favorable Early Breast Cancer

    International Nuclear Information System (INIS)

    Poetter, Richard; Gnant, Michael; Kwasny, Werner; Tausch, Christoph; Handl-Zeller, Leonore; Pakisch, Brigitte; Taucher, Susanne; Hammer, Josef; Luschin-Ebengreuth, Gero; Schmid, Marianne; Sedlmayer, Felix; Stierer, Michael; Reiner, Georg; Kapp, Karin; Hofbauer, Friedrich; Rottenfusser, Andrea; Poestlberger, Sabine; Haider, Karin; Draxler, Wolfgang; Jakesz, Raimund

    2007-01-01

    Purpose: In women with favorable early breast cancer treated by lumpectomy plus tamoxifen or anastrazole, it remains unclear whether whole breast radiotherapy is beneficial. Methods and Material: Between January 1996 and June 2004, the Austrian Breast and Colorectal Cancer Study Group (ABCSG) randomly assigned 869 women to receive breast radiotherapy ± boost (n 414) or not (n = 417) after breast-conserving surgery (ABCSG Study 8A). Favorable early breast cancer was specified as tumor size <3 cm, Grading 1 or 2, negative lymph nodes, positive estrogen and/or progesterone receptor status, and manageable by breast-conserving surgery. Breast radiotherapy was performed after lumpectomy with 2 tangential opposed breast fields with mean 50 Gy, plus boost in 71% of patients with mean 10 Gy, in a median of 6 weeks. The primary endpoint was local relapse-free survival; further endpoints were contralateral breast cancer, distant metastases, and disease-free and overall survival. The median follow-up was 53.8 months. Results: The mean age was 66 years. Overall, there were 21 local relapses, with 2 relapses in the radiotherapy group (5-y rate 0.4%) vs. 19 in the no-radiotherapy group (5.1%), respectively (p = 0.0001, hazard ratio 10.2). Overall relapses occurred in 30 patients, with 7 events in the radiotherapy group (5-y rate 2.1%) vs. 23 events in the no-radiotherapy group (6.1%) (p = 0.002, hazard ratio 3.5). No significant differences were found for distant metastases and overall survival. Conclusion: Breast radiotherapy ± boost in women with favorable early breast cancer after lumpectomy combined with tamoxifen/anastrazole leads to a significant reduction in local and overall relapse

  8. Favorable Cardiovascular Risk Profile Is Associated With Lower Healthcare Costs and Resource Utilization: The 2012 Medical Expenditure Panel Survey.

    Science.gov (United States)

    Valero-Elizondo, Javier; Salami, Joseph A; Ogunmoroti, Oluseye; Osondu, Chukwuemeka U; Aneni, Ehimen C; Malik, Rehan; Spatz, Erica S; Rana, Jamal S; Virani, Salim S; Blankstein, Ron; Blaha, Michael J; Veledar, Emir; Nasir, Khurram

    2016-03-01

    The American Heart Association's 2020 Strategic Goals emphasize the value of optimizing risk factor status to reduce the burden of morbidity and mortality. In this study, we aimed to quantify the overall and marginal impact of favorable cardiovascular risk factor (CRF) profile on healthcare expenditure and resource utilization in the United States among those with and without cardiovascular disease (CVD). The study population was derived from the 2012 Medical Expenditure Panel Survey (MEPS). Direct and indirect costs were calculated for all-cause healthcare resource utilization. Variables of interest included CVD diagnoses (coronary artery disease, stroke, peripheral artery disease, dysrhythmias, or heart failure), ascertained by International Classification of Diseases, Ninth Edition, Clinical Modification codes, and CRF profile (hypertension, diabetes mellitus, hypercholesterolemia, smoking, physical activity, and obesity). Two-part econometric models were used to study expenditure data. The final study sample consisted of 15 651 MEPS participants (58.5±12 years, 54% female). Overall, 5921 (37.8%) had optimal, 7002 (44.7%) had average, and 2728 (17.4%) had poor CRF profile, translating to 54.2, 64.1, and 24.9 million adults in United States, respectively. Significantly lower health expenditures were noted with favorable CRF profile across CVD status. Among study participants with established CVD, overall healthcare expenditures with optimal and average CRF profile were $5946 and $3731 less compared with those with poor CRF profile. The respective differences were $4031 and $2560 in those without CVD. Favorable CRF profile is associated with significantly lower medical expenditure and healthcare utilization among individuals with and without established CVD. © 2016 American Heart Association, Inc.

  9. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.

    Science.gov (United States)

    Contreras, Francisco; Prado, Carolina; González, Hugo; Franz, Dafne; Osorio-Barrios, Francisco; Osorio, Fabiola; Ugalde, Valentina; Lopez, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Alvaro; Pacheco, Rodrigo

    2016-05-15

    Dopamine receptor D3 (DRD3) expressed on CD4(+) T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 signaling affects T cell-mediated immunity remains unknown. In this study, we report that TCR stimulation on mouse CD4(+) T cells induces DRD3 expression, regardless of the lineage specification. Importantly, functional analyses performed in vivo using adoptive transfer of OVA-specific OT-II cells into wild-type recipients show that DRD3 deficiency in CD4(+) T cells results in attenuated differentiation of naive CD4(+) T cells toward the Th1 phenotype, exacerbated generation of Th2 cells, and unaltered Th17 differentiation. The reciprocal regulatory effect of DRD3 signaling in CD4(+) T cells favoring Th1 generation and impairing the acquisition of Th2 phenotype was also reproduced using in vitro approaches. Mechanistic analysis indicates that DRD3 signaling evokes suppressor of cytokine signaling 5 expression, a negative regulator of Th2 development, which indirectly favors acquisition of Th1 phenotype. Accordingly, DRD3 deficiency results in exacerbated eosinophil infiltration into the airways of mice undergoing house dust mite-induced allergic response. Interestingly, our results show that, upon chronic inflammatory colitis induced by transfer of naive CD4(+) T cells into lymphopenic recipients, DRD3 deficiency not only affects Th1 response, but also the frequency of Th17 cells, suggesting that DRD3 signaling also contributes to Th17 expansion under chronic inflammatory conditions. In conclusion, our findings indicate that DRD3-mediated signaling in CD4(+) T cells plays a crucial role in the balance of effector lineages, favoring the inflammatory potential of CD4(+) T cells. Copyright © 2016 by The American Association of Immunologists, Inc.

  10. Gender related differences in response to "in favor of myself" wellness program to enhance positive self & body image among adolescents.

    Science.gov (United States)

    Golan, Moria; Hagay, Noa; Tamir, Snait

    2014-01-01

    Physical, neurological and psychological changes are often experienced differently by male and female adolescents. Positive self-esteem, emotional well-being, school achievements, and family connectedness are considered as protective factors against health-compromising behaviors. This study examines the gender differences in respect to the effect of a school-based interactive wellness program--"In Favor of Myself"--on self-image, body image, eating attitudes and behaviors of young adolescents. Two hundred and ten adolescents (mean age 13.5) participated in the intervention group, 55% were girls and 45% boys. Program consisted of eight 90-minutes structured sessions integrated into a regular school coping skills curriculum. The program focused on self-esteem, self-image, body image, media literacy and cognitive dissonance. The overall impact of the program and the study protocol were previously published. Overall, there are gender related differences in respect to body image and self-image in young adolescents in response to "In Favor of Myself". Compared to boys, girls reported at baseline higher self-esteem, being more contingent by appearance, and their self-image was more influenced by popularity, appearance, interpersonal communication and admired people. Furthermore girls presented greater gap between current body figure and perceived ideal figure. Not only were girls more dissatisfied with their body, but they were more active in attempts to become and/or remain "thin". At program termination, gender × time effect was detected in reduction of self-worth contingent by others, change in importance given to achievements at schools, parents' perceptions, as well as the impact of comparisons to friends and family members on self-image. Girls exhibited more gains than boys from 'In Favor of Myself' which raise the questions about how effective would be the program when delivered in mixed gender groups vs. mono-gender groups.

  11. Gender related differences in response to "in favor of myself" wellness program to enhance positive self & body image among adolescents.

    Directory of Open Access Journals (Sweden)

    Moria Golan

    Full Text Available BACKGROUND: Physical, neurological and psychological changes are often experienced differently by male and female adolescents. Positive self-esteem, emotional well-being, school achievements, and family connectedness are considered as protective factors against health-compromising behaviors. This study examines the gender differences in respect to the effect of a school-based interactive wellness program--"In Favor of Myself"--on self-image, body image, eating attitudes and behaviors of young adolescents. METHODS: Two hundred and ten adolescents (mean age 13.5 participated in the intervention group, 55% were girls and 45% boys. Program consisted of eight 90-minutes structured sessions integrated into a regular school coping skills curriculum. The program focused on self-esteem, self-image, body image, media literacy and cognitive dissonance. The overall impact of the program and the study protocol were previously published. RESULTS: Overall, there are gender related differences in respect to body image and self-image in young adolescents in response to "In Favor of Myself". Compared to boys, girls reported at baseline higher self-esteem, being more contingent by appearance, and their self-image was more influenced by popularity, appearance, interpersonal communication and admired people. Furthermore girls presented greater gap between current body figure and perceived ideal figure. Not only were girls more dissatisfied with their body, but they were more active in attempts to become and/or remain "thin". At program termination, gender × time effect was detected in reduction of self-worth contingent by others, change in importance given to achievements at schools, parents' perceptions, as well as the impact of comparisons to friends and family members on self-image. CONCLUSIONS: Girls exhibited more gains than boys from 'In Favor of Myself' which raise the questions about how effective would be the program when delivered in mixed gender groups

  12. The Effect of “In Favor of Myself”: Preventive Program to Enhance Positive Self and Body Image among Adolescents

    Science.gov (United States)

    Golan, Moria; Hagay, Noaa; Tamir, Snait

    2013-01-01

    Background Positive self-esteem, emotional well-being, school achievements and family connectedness are considered protective factors against health-compromising behaviors. This study examined the effect of an interactive, community-based, media literacy and dissonance wellness program, In Favor of Myself, on the self-image, body image, eating attitudes and behavior of young adolescents. A preliminary cohort study was conducted among 972 program participants who did not take part in the controlled trial. Over 75% of participants said they would recommend the program to their friends. Methods A controlled trial was conducted to evaluate program acceptability, efficacy and effectiveness among 259 participants (210 in the intervention group and 49 in the control group), aged 12–14 years, who completed questionnaires during at least two assessment times. Program materials were provided, along with leaders' training, in order to ensure quality program delivery and creation of a wide network of committed program leaders. Results The program significantly reduced drive for thinness and self-worth contingent upon others' approval, the gap between current body figure and ideal figure, and the impact of mood on girls' self-image. Superiority was found among those participating in the intervention group with respect to recognizing media strategies, the influence of media on desire to change, and the influence of appearance on self-confidence and drive for thinness. Conclusions In Favor of Myself shows promising results for strengthening adolescents' ability to cope with the challenges of their life stage. Suggestions for improving In Favor of Myself are presented. PMID:24265681

  13. Campo magnético discontinuo en adultos con hipertensión arterial esencial

    Directory of Open Access Journals (Sweden)

    Enrique Arce Morera

    2003-06-01

    Full Text Available Se realizó un estudio piloto a 44 casos remitidos al Departamento de Fisioterapia de nuestro municipio con diagnóstico de hipertensión arterial esencial ligera y moderada, aplicándosele 15 sesiones de campo magnético discontinuo durante 15 min. Para buscar el grado de efectividad se utilizó el método estadístico de Mc Nemar, resultando muy significativa la reducción en los valores de la presión arterial, principalmente la máxima. Hubo un favorable efecto socioeconómico, pues se ahorró en el empleo de medicamentos $481.32 al aplicarse esta técnica.A pilot study was made on 44 cases referred to the Department of Physiotherapy of our municipality and diagnosed with light and moderate essential blood hypertension. They were administered 15 sessions of discontinuous electromagnetic field for 15 minutes. To find the level of effectiveness, we used the McNemar´s statistical method and the reduction in blood pressure values, mainly the maximum pressure was really very significant. There was also a favorable socio-economic effect since the saving in terms of drug consumption was $481.32 after the application of this technique.

  14. Modelización financiera con Excel

    Directory of Open Access Journals (Sweden)

    Lafuente Robledo, M.

    1998-01-01

    Full Text Available La enseñanza de la Matemática de las Operaciones Financieras ha experimentado durante la década de los noventa una transformación profunda como consecuencia de la progresiva introducción de los programas informáticos. Las hojas de cálculo, dada su gran facilidad de uso, su flexibilidad y su utilización generalizada, han sido una de las herramientas disponibles más potentes para el tratamiento de problemas financieros. De ahí que su incorporación a los programas docentes de esta disciplina se hayan convertido en una norma casi obligada para garantizar la calidad de la enseñanza en esta materia. No obstante, es preciso tener en cuenta que para aplicaciones de alto nivel se requieren programas más especializados (por ejemplo, para gestión de carteras y que cada vez están más extendidas otras herrramientas informáticas de cálculo avanzado como los programas de cálculo numérico (por ejemplo, las aplicaciones financieras específicas de Matlab o de cálculo simbólico (Mathematica, Maple, Matlab, Derive, etc.. De ahí que la hoja de cálculo haya dejado de ser el único programa informático de uso generalizado para el tratamiento de operaciones financieras, y que progresivamente sea preciso incorporar las nuevas aplicaciones en los curricula del alumno. La utilización de las hojas de cálculo en la modelización de problemas de matemática financiera representa importantes ventajas didácticas: · Dado el carácter eminentemente práctico de la misma, simplifica en gran medida la materia a impartir, ya que con los principios y razonamientos elementales permite prescindir del desarrollo de buen número de las fórmulas que la matemática financiera plantea para realizar valoraciones. · Como consecuencia se produce un gran ahorro de tiempo en cuanto a las necesidades de clases magistrales, lo cual permite dedicar más tiempo a la explicación detallada y pormenorizada de los conceptos fundamentales. · Desde el punto de vista

  15. Competencia social y autoestima en adolescentes con fobia social (Social Competence and Self-Esteem in Adolescents with Social Phobia

    Directory of Open Access Journals (Sweden)

    Antonio Vallés Arándiga

    2014-06-01

    Full Text Available RESUMEN: El presente trabajo se enmarca en un proyecto para la detección e intervención temprana de adolescentes con fobia social en el contexto comunitario, que ha mostrado reiteradamente ser eficaz en la reducción y eliminación de este problema en la población de adolescentes que cursan estudios de Educación Secundaria Obligatoria (ESO y postobligatoria. Se presentan los resultados de la investigación realizada con alumnos de 3º de ESO con fobia social generalizada en varios Institutos de Educación Secundaria de Alicante. Según Olivares y García-López (1998, la eficacia terapéutica del paquete de tratamiento Intervención en Adolescentes con Fobia Social (IAFS mostró el incremento de la competencia social y la mejora de la autoestima en adolescentes que fueron diagnosticados con el referido trastorno, frente a un grupo de control pasivo (sin tratamiento y un grupo de control activo (tratamiento con un programa de estrategias de aprendizaje que incluía contenidos de exposición a situaciones sociales. Todos los tratamientos fueron desarrollados en los centros educativos. Los resultados obtenidos a favor del grupo de tratamiento IAFS en las variables de competencia social (informados por el tutor y por los padres y de autoestima se mantuvieron en el seguimiento luego de 6 meses. ABSTRACT:This study is part of a project for the detection and early intervention of adolescents with social phobia in the community context that it has shown repeatedly to be effective in the reduction and elimination of this problem in the population of teenagers who are studying in a Compulsory Secondary Education (ESO and post-compulsory. It shows the results of the research conducted with students of 3rd of ESO with social phobia, generalized in several Secondary Education Institutes (IES of Alicante. According to Olivares and Garcia-Lopez (1998, the therapeutic efficacy of the treatment package Intervention in Adolescents with Social Phobia (IAFS

  16. Factores determinantes del compromiso por el trabajo o work engagement. El caso de la Asociación Malagueña en favor de las Personas con Discapacidad Intelectual-ASPROMANIS

    OpenAIRE

    Benítez Saña, Rosa María

    2015-01-01

    El presente Trabajo Fin de Grado tiene como objetivo el estudio del work engagement, que ha captado recientemente el interés de los investigadores, surgiendo como un concepto novedoso y considerado opuesto al burnout, y estudiado por la Psicología Ocupacional Positiva desde un enfoque totalmente distinto, cuyo fin es fomentar las potencialidades y fortalezas de los trabajadores, y su óptimo funcionamiento desde un punto de vista positivo. Es un constructo tridimensional caracterizado por vig...

  17. Em favor da talassografia

    Directory of Open Access Journals (Sweden)

    Jean-Louis Boudou

    2001-01-01

    Full Text Available A Talassografia (“descrição do mar” interessa-sepelos impactos físicos, biológicos, ecológicos... culturais da violenta antropização dos ambientes costeiros (oceânicos e continentais, caracterizados pelaexigüidade, vulnerabilidade, fragilidade e plasticidade. Como o Brasil é um “país marítimo”, os geó-grafos (os talassógrafos brasileiros são convidadosa intensificar suas pesquisas nas áreas costeiras e acriar novas estruturas para divulgá-las: Revista, Encontros, Associação, Pós-Graduação... tudo em prolda talassografia.

  18. Desayuno con partículas la ciencia como nunca antes se ha contado

    CERN Document Server

    Fernández-Vidal, Sonia

    2013-01-01

    Tienes en las manos un ensayo sobre física cuántica, así es. Un momento, por favor, ¡espera! No dejes que eso te asuste y sueltes el libro de golpe. ¿Aceptarías una invitación a desayunar? Si aceptas esta proposición y te aventuras a navegar entre estas páginas, descubrirás un universo tan maravilloso como desconcertante. La teoría cuántica es una de las más bellas y asombrosas de la ciencia. Las reglas que sigue son alocadas en comparación con nuestro día a día. Son anti-intuitivas. Al adentrarnos en el mundo cuántico se ponen en jaque nuestras creencias sobre la realidad, también de nuestra realidad cotidiana. Sonia Fernández-Vidal, escritora y doctora en Física Cuántica, y Francesc Miralles, escritor y periodista, nos invitan a un divertido desayuno al que están invitadostambién asistirán Newton, Einstein, Heisenberg y otros famosos físicos de la historia. Entre magdalenas, donuts, café con leche y zumos de naranja, emprenderemos un fascinante y revelador viaje a los orígenes del...

  19. Eficacia de un tratamiento grupal cognitivo-conductual en pacientes con trastornos de ansiedad

    Directory of Open Access Journals (Sweden)

    MANUEL SÁNCHEZ GARCÍA

    2003-01-01

    Full Text Available Este estudio evalúa los datos obtenidos por 44 sujetos con diversos trastornos de ansiedad a los que se les indicó terapia grupal cognitivo-conductual. No se apreciaron diferencias significativas entre los individuos sometidos a tratamiento y el grupo control en variables sociodemográficas, estrés previo, alexitimia, estilo de afrontamiento y diagnóstico. Los resultados indican que la evolución clínica en los sujetos que asistieron a la mayoría de las sesiones es significativamente más favorable que en los sujetos-control: El seguimiento de un año muestra que son más los sujetos que reciben el alta (73.68% vs. 28% y los que ven reducida la dosis de benzodiacepinas prescrita (44.44% vs. 10.52% respecto a los controles. Entre las medidas post-tratamiento obtenidas, se hallaron disminuciones en las puntuaciones de ansiedad-estado, depresión y malestar emocional (p< .05; también mejoró, aunque con menos valor estadístico, la apreciación de su estado físico y disminuyó la frecuencia del malestar físico percibido.

  20. Equinoterapia en niños con autismo

    OpenAIRE

    Martinez Alvernia, Carlos Francisco

    2015-01-01

    Introducción: Autismo es un trastorno del desarrollo caracterizado por compromiso en interacción social, habilidades de lenguaje, presentando rituales con estereotipias. Sin tratamientos curativos, actualmente se buscan terapias alternativas. Un incremento de la literatura científica de terapias asistidas con animales se ha evidenciado, demostrando mejoría en pacientes autistas con la equinoterapia. Objetivo: Realizar una revisión sistemática de la literatura para evaluar efectividad de la eq...

  1. Uso del condón en hombres con parejas no estables en la Ciudad de México

    Directory of Open Access Journals (Sweden)

    Nieto-Andrade Benjamín

    1999-01-01

    Full Text Available Objetivo. Analizar la asociación de variables sociodemográficas en la utilización del condón durante prácticas sexuales vaginales con parejas no estables. Material y métodos. Los datos provienen de una encuesta probabilística sobre comportamiento sexual aplicada en 1992-1993 a una muestra de hogares en la Ciudad de México y su área conurbada. De 8 068 hombres de 15 a 60 años de edad que proporcionaron información, se seleccionaron 1 535 cuya última relación sexual -con penetración vaginal- había sido con una pareja no estable. Primero se realizó un análisis por componentes principales, para agrupar aquellas variables con dimensiones subyacentes comunes y, a partir de ellos y de algunas variables individuales, se efectuó una regresión logística. Resultados. Las variables que midieron conocimientos sobre el SIDA y sus mecanismos de transmisión y prevención, no tuvieron una relación estadísticamente significativa (p< 0.05 con haber usado condón en la última relación sexual vaginal con una pareja no estable (variable dependiente. En su lugar, las variables que sí presentaron una relación estadísticamente significativa con la variable dependiente, fueron: visión del placer del sexo con condón o sin penetración; autoeficacia para realizar sexo sin penetración; autocompulsión en el uso del condón asociado al SIDA como enfermedad de mayor temor; percepción sobre el carácter evitable de la infección y sobre la efectividad del condón; estado civil; escolaridad; y número de episodios de enfermedades de transmisión sexual (ETS en toda la vida. Conclusiones. Aunque la provisión de información es importante en las estrategias educacionales de prevención sobre VIH/SIDA, el fomento de una percepción individual y colectiva favorable (placentera sobre el condón, el sexo seguro y la autoeficacia para poner en práctica medidas preventivas contra la infección por VIH, puede ser de mayor importancia para adoptar el uso

  2. Atomistic modeling to investigate the favored composition for metallic glass formation in the Ca-Mg-Ni ternary system.

    Science.gov (United States)

    Zhao, S; Li, J H; An, S M; Li, S N; Liu, B X

    2017-05-17

    A realistic interatomic potential was first constructed for the Ca-Mg-Ni system and then applied to Monte Carlo simulations to predict the favored composition for metallic glass formation in the ternary system. The simulations not only predict a hexagonal composition region, within which the Ca-Mg-Ni metallic glass formation is energetically favored, but also pinpoint an optimized sub-region within which the amorphization driving force, i.e. the energy difference between the solid solution and disordered phase, is larger than that outside. The simulations further reveal that the physical origin of glass formation is the solid solution collapsing when the solute atom exceeds the critical solid solubility. Further structural analysis indicates that the pentagonal bi-pyramids dominate in the optimized sub-region. The large atomic size difference between Ca, Mg and Ni extends the short-range landscape and facilitates the development of a hybridized packing model in the medium-range, and eventually enhancing the glass formation in the system. The predictions are well supported by the experimental observations reported so far, and could be of help for designing the ternary glass formation.

  3. Smoking Counteracts the Favorable Effect of Exercise Training on Endothelial Function in Patients with Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Shinji Sato

    2013-01-01

    Full Text Available Background Exercise training can improve endothelial function in patients with diabetes. We hypothesized that the favorable effect of exercise training on endothelial function in patients with diabetes is counteracted by cigarette smoking. Purpose To assess whether there is a difference in the effect of exercise on endothelial function in smokers and non-smokers with type 2 diabetes. Methods We performed a 3-month controlled trial in 27 never-smoking and 17 smoking individuals with type 2 diabetes who participated in a home-based walking program. The percentage decrease in post-exercise ankle-brachial pressure index (ABI, which is an index of endothelial function, was assessed at baseline and after 3 months. Results Compared to the smoking group, the never-smoking group showed a more significant improvement in post exercise ABI during the 3 months of home-based training (interaction, P < 0.01. Conclusions These results indicate that smoking may counteract the favorable effects of exercise training on endothelial function. Endothelial function plays an important role in the prevention of cardiovascular disease among patients with diabetes. Therefore, a Certified Diabetes Educator should strongly advise diabetic patients not to smoke.

  4. Impact of collateral circulation status on favorable outcomes in thrombolysis treatment: A systematic review and meta-analysis.

    Science.gov (United States)

    Wufuer, Alimu; Wubuli, Atikaimu; Mijiti, Peierdun; Zhou, Jun; Tuerxun, Shabier; Cai, Jian; Ma, Jianhua; Zhang, Xiaoning

    2018-01-01

    Collateral circulation affects the prognosis of patients with acute ischemic stroke (AIS) treated by thrombolysis. The present study performed a systematic assessment of the impact of the collateral circulation status on the outcomes of patients receiving thrombolysis treatment. Relevant full-text articles from the Cochrane Library, Ovid, Medline, Embase and PubMed databases published from January 1, 2000 to November 1, 2016 were retrieved. The quality of the studies was assessed and data were extracted by 2 independent investigators. The random-effects model was used to estimate the impact of good vs. poor collateral circulation, as well as baseline characteristics, on the outcome within the series presented as risk ratios. Subgroup analyses explored the potential factors that may interfere with the effects of the collateral circulation status on the outcome. A total of 29 studies comprising 4,053 patients were included in the present meta-analysis. A good collateral circulation status was revealed to have a beneficial effect on favorable functional outcome (modified Rankin scale, 0-3 at 3-6 months; Pcollateral circulation. Good collateral circulation was also associated with a lower rate of symptomatic intracranial hemorrhage (Pcollateral circulation was demonstrated to have a favorable prognostic value regarding the outcome for patients with AIS receiving thrombolysis treatment. Assessment of collateral circulation and penumbra area during pre-treatment imaging within an appropriate time-window prior to thrombolytic therapy will therefore improve the identification of AIS patients who may benefit from thrombolysis treatment.

  5. Uranium favorability of precambrian rocks in the Badger Flats - Elkhorn Thrust Area, Park and Teller Counties, Colorado

    International Nuclear Information System (INIS)

    Gallagher, G.L.

    1976-10-01

    The area is approximately 1,800 square miles and extends from Cripple Creek northward to Fairplay and Bailey. The Precambrian rocks include the metamorphic sequences of the Idaho Springs Formation and the Boulder Creek Granodiorite, Silver Plume Granite, Pikes Peak Granite, and Redskin Granite. The known uranium deposits in the area include six vein deposits, three pegmatite occurrences, and one zone of probable secondary enrichment; they have not yielded any significant production. The vein deposits are probably the result of downward percolation of ground water. The zone of secondary uranium enrichment may have formed above a volcanic pipe, vein, or tuffaceous lake bed. Favorability in the area is considered good for both vein and large, disseminated, low-grade uranium deposits. On the bases of known uranium occurrences, favorable structures and host rocks, and a water-sampling program, recommendations are given for exploration. The occurrences in the area have substantial similarities with the Rossing deposit in South-West Africa and the Wheeler Basin uranium occurrence in Grand County, Colorado. 6 figures, 9 tables

  6. Mi palabra favorita. Una actividad con vídeo

    Directory of Open Access Journals (Sweden)

    Susana Cañuelo Carrión

    2012-08-01

    Full Text Available Mi palabra favorita es un actividad que surge a partir de la propuesta que realizael Instituto Cervantes con la web El día E (www.eldiae.es. Este portal fue creado enconmemoración del día del español, que se celebra desde 2009 el último sábado dejunio. Para festejar la vitalidad de la lengua y el interés mundial que despierta, hablantesy aprendientes de todo el mundo pueden explicar en dicho portal cuál es su palabrafavorita. Y pueden hacerlo con un texto, con un pictograma o con un vídeo.

  7. Anestesia para cesárea en paciente con acondroplasia

    OpenAIRE

    Osorio Rudas, Walter; Socha García, Nury Isabel; Upegui, Alejandro; Ríos Medina, Ángela; Moran, Adrian; Aguirre Ospina, Oscar; Rivera, Carlos

    2012-01-01

    Introducción: En gestantes acondroplásicas se recomienda el parto por cesárea con anestesia general; sin embargo, recientemente se ha reportado el uso de técnicas conductivas con resultados adecuados. Objetivo:Describir el manejo anestésico de una paciente con acondroplasia programada para cesárea utilizando anestesia combinada espinal-epidural. Métodos y resultados:Mostramos el caso de una primigestante acondroplásica con 110 cm de estatura y embarazo de 37 semanas, en quien se realizó cesár...

  8. Plasma rico en plaquetas en pacientes con gonartrosis

    OpenAIRE

    Álvarez López, Alejandro; Ortega González, Carlos; García Lorenzo, Yenima; Arias Sifontes, Joanka; Ruiz de Villa Suárez, Abel

    2013-01-01

    Fundamento: la aplicación del plasma rico en plaquetas se ha convertido en una modalidad de tratamiento para pacientes con gonartrosis, tanto de forma aislada como en combinación con otros procedimientos. Objetivo: actualizar al personal médico sobre aspectos esenciales relacionados con la aplicación del plasma rico en plaquetas en pacientes con gonartrosis. Método: se realizó una revisión bibliográfica de un total de 300 artículos originales publicados en Pubmed, Hinari y Medline, mediante e...

  9. Relación del perfil salival con el grado de inmunosupresión en pacientes infectados con VIH con y sin tratamiento antirretroviral

    OpenAIRE

    Vera Cruz, Moisés; Cornejo Salaza, José; Chiyong, Teresa Evaristo; Arevalo Abanto, Jorge A.; Villanueva Vílchez, Hugo G.

    2014-01-01

    El objetivo del estudio fue evaluar el perfil salival de pacientes con infección por VIH con y sin Tratamiento Antirretroviral de Gran Actividad (TARGA), por medio de la evaluación de los síntomas de hipofunción salival (Xerostomía, Disgeusia, Disfagia y Susceptibilidad de desarrollar úlceras orales), la Tasa de Flujo salival no estimulado, el pH salival y la viscosidad salival; estableciendo su relación con el Grado de Inmunosupresión, evaluado por medio del Recuento de Linfocitos CD4/μl. Se...

  10. MODELADO CON REDES DE PETRI E IMPLEMENTACIÓN CON GRAFCET DE UN SISTEMA DE MANUFACTURA FLEXIBLE CON PROCESOS CONCURRENTES Y RECURSOS COMPARTIDOS

    OpenAIRE

    Johanna Stella Castellanos Arias; Leonardo Enrique Solaque Guzmán

    2010-01-01

    En este trabajo, se presenta el modelado de un Sistema de Manufactura Flexible (SMF), con procesos concurrentes y recursos compartidos mediante Sistemas a Eventos Discretos (SED), específicamente Redes de Petri (RdP), y GRAFCET. El SMF se plantea como un modelo hipotético que se modela con una RdP con el objeto de identificar su dinámica y hallar la secuencia óptima de funcionamiento del sistema. Se desarrolló un modelo matemático que permite estimar el vector de tiempo acumulado de un proces...

  11. Factores de riesgo asociados con la hipertensión arterial en los trabajadores de la oficina central del MINBAS

    Directory of Open Access Journals (Sweden)

    Lourdes Rodríguez Domínguez

    1997-10-01

    Full Text Available Se realizó un estudio descriptivo del total de hipertensos que laboran en el Ministerio de la Industria Básica, en el período de enero a diciembre de 1995 con el objetivo de identificar los factores de riesgo que favorezcan la aparición de la hipertensión arterial y sus diferencias según el sexo. El grupo de edad más afectado fue el comprendido entre 50 y 59 años, con predominio del sexo masculino. La historia familiar de hipertensión arterial (96,5 %, la cardiopatía isquémica (32,60 % y la hipercolesterolemia (30,60 %, estuvo presente aunque su relación con el sexo no fue significativa. La hipertensión arterial se vio relacionada de forma significativa con la obesidad en el sexo femenino y con el hábito de fumar, el sedentarismo y la categoría ocupacional de dirigente en el sexo masculino.A descriptive study of the total number of hypertensives working at the Ministry of the Basic Industry from January to December, 1995, was conducted aimed at identifying those risk factors favoring the appearance of arterial hypertension and their differences according to sex. The age group 50-59 was the most affected and there was a predominance of the male sex. The family history of arterial hypertension (96.5 %, ischemic cardiopathy (32.60 % and hypercholesterolemia (30.60 % were present eventhough their relationship with sex was no significant. Arterial hypertension was markedly connected with obesity in the female sex and with the smoking habit, sedentarism, and the leader occupational category in the male sex.

  12. Gestión del tiempo en alumnado universitario con diferentes niveles de rendimiento académico

    Directory of Open Access Journals (Sweden)

    Angélica Garzón Umerenkova

    2017-09-01

    Full Text Available Resumen En este trabajo se estudia la relación entre gestión del tiempo y rendimiento académico en el alumnado universitario. La hipótesis de partida es que los estudiantes con alto nivel de habilidades en gestión del tiempo obtienen mejores resultados de aprendizaje. Se ha utilizado una muestra de 494 estudiantes universitarios de primer año, en dos universidades colombianas. A esta muestra se administró una adaptación al español del Time Management Behavior Questionnaire (TMBQ, y se recogieron datos sobre las calificaciones académicas en su primer año en la universidad. De manera complementaria, se han celebrado cuatro grupos focales con alumnado de bajo y alto nivel de rendimiento, accediendo a sus experiencias, opiniones y valoraciones en relación con la gestión del tiempo. Los resultados obtenidos indican la existencia de una cierta relación positiva entre las dos variables analizadas, en línea con los hallazgos de estudios previos. Al comparar la gestión del tiempo entre subgrupos de estudiantes que alcanzan las mejores y peores calificaciones, se observan diferencias a favor de los primeros, particularmente en la sub-escala relativa a sus percepciones sobre el control del tiempo. Los discursos de grupo reflejan también mejores conductas autorregulatorias en el manejo del tiempo por parte del alumnado de alto nivel de rendimiento. De acuerdo con estos resultados, se hacen recomendaciones sobre el entrenamiento del alumnado universitario de primer año en estrategias para la gestión del tiempo.

  13. Política y gestión en salud de las gobernaciones en Venezuela con el advenimiento de la descentralización: tendencias en el neoliberalismo

    OpenAIRE

    Jennifer Fuenmayor; Haydée Ochoa Henríquez

    2013-01-01

    Con el curso de la descentralización político territorial, se introdujeron prácticas de la empresa privada en ambulatorios y hospitales con el propósito de reducir al Estado. Partimos del supuesto de que en las gobernaciones venezolanas ha predominado una política y gestión en salud, a favor de un modelo de economía de mercado, con rasgos tecnocráticos y con base en las propuestas de la Nueva Gestión Pública (NGP). Esta investigación tiene como propósito, explicar la política y gestión públic...

  14. Enfermedad periodontal en pacientes con discapacidad en custodia versus pacientes con discapacidad independientes

    Directory of Open Access Journals (Sweden)

    Fermín-Guerrero-Del Ángel

    2012-01-01

    Full Text Available Objetivo: Identificar el estado de salud periodontal en pacientes con discapacidad en custodia versus pacientes independientes en su higiene oral. Material y métodos: Se examinaron pacientes con discapacidad, ambos sexos, 3 a 19 años que acuden al Servicio de Odontopediatría del Centro de Rehabilitación Infantil Teletón (CRIT Tamaulipas mediante revisión de cavidad oral y aplicación del Índice de Higiene Oral Simplificado (IHOS, Índice Periodontal Comunitario de la Necesidad de Tratamiento (IPCNT y entrevista con su cuidador primario. Se agruparon en dos categorías: Independientes y de Custodia. Resultados: En el total de la muestra la Media y Desviación estándar (D.E. de IPCNT fue de 0.89±0.54, así como el IHOS de 1.88±0.77. El IPCNT en pacientes con discapacidad de Custodia fue 0.91±0.57 e Independientes de 0.86±0.49 (p=0.70, IHOS en pacientes de Custodia 1.89±0.78 e Independientes 1.87±.0.74 (p=.93. IPCNT en géneros masculino 1.03±0.54 y femenino 0.75±0.51 (p=.009. IHOS en pacientes que habitan área rural 2.41±1.25 y área urbana 1.83±0.68 (p=.02. Relación entre la edad y la necesidad de tratamiento periodontal (p=0.001. Frecuencia del cepillado del grupo Independientes 2.03±0.56 y de Custodia 2.00±0.75 (p=.84. Conclusiones: No existe diferencia en el estado de salud periodontal y el grado de higiene oral entre pacientes con discapacidad Independientes y de Custodia. La mayoría de los pacientes Independientes y de Custodia tienen una necesidad de tratamiento de Instrucción de Higiene Oral (TN1 y tienen Higiene Oral Regular.

  15. Efectos del tratamiento con litio sobre las funciones neurosicológicas de pacientes con trastorno bipolar de tipo I

    Directory of Open Access Journals (Sweden)

    Anabel Martínez Aran

    2008-11-01

    Full Text Available OBJETIVO: determinar si el tratamiento continuo con litio influye en el desempeño cognitivo de un grupo de pacientes eutímicos con trastorno afectivo bipolar I. MÉTODO: se evaluó el desempeño cognitivo usando pruebas neurosicológicas de atención, memoria y función ejecutiva en 20 pacientes eutímicos con trastorno afectivo bipolar I que no tomaban medicación, 20 pacientes eutímicos con trastorno afectivo bipolar I quienes continuaban regularmente el tratamiento con carbonato de litio, y un tercer grupo de 20 pacientes control. RESULTADOS: no se encontraron diferencias estadísticamente significativas entre los dos grupos de pacientes con trastorno afectivo bipolar. Sin embargo, al compararlos con el grupo control, su desempeño en términos de memoria verbal, viso-verbal y asociación semántica medida fue menor. DISCUSIÓN: los pacientes con trastorno afectivo bipolar I muestran deficiencias en términos de memoria verbal y viso-verbal que no pueden ser atribuidos al tratamiento regular con carbonato de litio. Por el contrario, estas deficiencias podrían ser consideradas como características de rasgo de este trastorno.

  16. Calidad de vida relacionada con la salud del niño y del adolescente con obesidad

    OpenAIRE

    Hurtado-Valenzuela, Jaime Gabriel; Álvarez-Hernández, Gerardo

    2014-01-01

    Objetivo Estimar la calidad de vida relacionada con la salud (CVRS) en un grupo de niños y adolescentes con obesidad de la ciudad de Hermosillo, Sonora, México. Métodos Se realizó un estudio transversal utilizando el cuestionario PedsQL® para comparar la CVRS de 200 niños y adolescentes con obesidad al igual que a sus padres, con dos grupos de control, uno de la comunidad (n=400) y otro grupo de usuarios (n=200) del Hospital Infantil del Estado de Sonora. Las diferencias en la CVRS fueron eva...

  17. Factores de mal pronóstico en pacientes internados con Neutropenia al inicio del episodio febril Prognostic risk factors for serious complications in an inpatient population with neutropenia at the onset of a febrile episode

    Directory of Open Access Journals (Sweden)

    Carlos Gómez Roca

    2006-10-01

    Full Text Available Los pacientes con neutropenia y fiebre constituyen una población heterogénea con riesgo variable para el desarrollo de complicaciones serias y mortalidad. El objetivo de este trabajo es identificar factores que, presentes al ingreso, estuvieran asociados a mayor riesgo de complicaciones graves en pacientes que se internan por neutropenia y fiebre. Se trata de un estudio de seguimiento de una cohorte de 238 episodios de neutropenia y fiebre (neutrófilos 38.3 °C en 167 pacientes internados en sala general en nuestra institución desde 1997 a 2004. Ochenta y dos por ciento de los pacientes tenían enfermedad hematológica, 14% tumores sólidos y 4% no asociados a quimioterapia. Se registraron 67 eventos adversos (46% de insuficiencia renal, 27% de hipotensión refractaria, 15% de insuficiencia respiratoria y 12% con sangrado mayor. Se hallaron diferencias significativas en presencia de comorbilidades previas, temperatura mayor a 39 °C, frecuencia cardíaca mayor a 120 latidos por minuto, frecuencia respiratoria mayor a 24 por minuto, tensión arterial sistólica menor a 90 mm Hg, presencia de 3 o más valores de laboratorio alterados al ingreso, presencia de foco clínico y hemocultivos positivos. En el análisis multivariado de regresión logística mantuvieron asociación independiente con mayor riesgo de eventos graves: hipotensión arterial sistólica (OR=7, pPatients with neutropenia and fever conform a heterogeneous population with a variable risk of serious complications and mortality. The goal of this study was to identify prognostic risk factors present at the beginning of the episode, for adverse events and serious complications in patients admitted in a general ward with fever and neutropenia. A cohort of 238 episodes with neutropenia and fever (neutrophils 38.3 °C in 167 patients admitted to our general hospital between 1997 and 2004 was followed. Eighty two percent of the patients had hematologic malignancies, 14% solid tumors

  18. Health care provider experience with canagliflozin in real-world clinical practice: favorability, treatment patterns, and patient outcomes

    Directory of Open Access Journals (Sweden)

    Bolge SC

    2017-06-01

    Full Text Available Susan C Bolge,1 Natalia M Flores,2 Shu Huang,3 Jennifer Cai1 1Janssen Scientific Affairs, LLC, Titusville, NJ, 2Kantar Health, Foster City, CA, 3Kantar Health, New York, NY, USA Purpose: This study describes how health care providers approach canagliflozin for the treatment of patients with type 2 diabetes mellitus (T2DM in the real world.Patients and methods: An Internet-based questionnaire was completed by 101 endocrinologists, 101 primary care physicians, and 100 nurse practitioners/physician assistants (NP/PAs. Health care providers were required to have experience prescribing or managing patients using canagliflozin to be included in the study. Health care providers compared canagliflozin with other T2DM medication classes on clinical characteristics, costs, and patient satisfaction. Confidence in canagliflozin was also measured. Health care providers reported their canagliflozin prescribing experience and good candidate characteristics for treatment. Finally, providers reported on patient outcomes among those receiving canagliflozin. All variables were compared across provider type.Results: Health care providers reported higher favorability for canagliflozin for blood pressure and body weight compared with dipeptidyl peptidase-4 (DPP-4 inhibitors and higher favorability for effect on blood pressure, body weight, treatment satisfaction, and glycosylated hemoglobin (HbA1c compared with sulfonylureas (SUs, with differences observed for effect on blood pressure. Health care providers reported being very/extremely confident (55%–74% with canagliflozin as a second- to fourth-line treatment. The top 3 characteristics reported by the providers, in terms of describing a good candidate for canagliflozin, include those concerned about their weight, insurance coverage/affordability, and avoiding injectable treatments. Finally, providers reported often/always observing patients’ lowering or controlling HbA1c (82%–88% and improvement in overall

  19. CONSIDERACIONES RELACIONADAS CON LAS INSPECCIONES DE SOFTWARE

    Directory of Open Access Journals (Sweden)

    Bexy Alfonso Espinosa

    2006-04-01

    Full Text Available

     

     

    Las consideraciones que en el presente trabajo se reflejan están enfocadas a enfatizar la importancia y necesidad de la aplicación de técnicas de verificación como las inspecciones de software, en la industria de software. Especialmente si de pequeñas y medianas empresas se trata pues en ellas recae la responsabilidad de lograr una industria de software de excelencia y con la calidad requerida en países en vías de desarrollo. Se analizan además, una serie de autores y las investigaciones que han realizado relativas a la concepción del proceso de inspección de software y los recursos y personal que deben tenerse en cuenta para ello.

  20. derechos de las personas con VIH

    Directory of Open Access Journals (Sweden)

    Ana Elena Badilla

    2007-01-01

    Full Text Available El marco constitucional y legal de Costa Rica, incluida la jurisprudencia de la Sala Constitucional de la Corte Suprema de Justicia, es fiel garante de los derechos humanos. Además, la existencia de un amplio marco jurídico internacional vigente en el país sobre protección de tales derechos contribuye a llenar las lagunas que presenta la legislación nacional. Particularmente destacable ha sido el papel jugado por la citada Sala Constitucional en la defensa de los derechos humanos de las personas afectadas por el virus de inmunodeficiencia humana (VIH, en especial al garantizarles sus derechos a los medicamentos antirretrovirales. También la Defensoría de los Habitantes ha instado en múltiples ocasiones a las instituciones públicas a impulsar políticas que permitan alcanzar los fines previstos en la legislación sobre la materia, la cual presenta aún importantes vacíos en relación con la perspectiva de género, la población joven, los derechos de la personalidad o el ámbito laboral, entre otros.