WorldWideScience

Sample records for fast on-line identification

  1. On-Line Impact Load Identification

    Directory of Open Access Journals (Sweden)

    Krzysztof Sekuła

    2013-01-01

    Full Text Available The so-called Adaptive Impact Absorption (AIA is a research area of safety engineering devoted to problems of shock absorption in various unpredictable scenarios of collisions. It makes use of smart technologies (systems equipped with sensors, controllable dissipaters and specialised tools for signal processing. Examples of engineering applications for AIA systems are protective road barriers, automotive bumpers or adaptive landing gears. One of the most challenging problems for AIA systems is on-line identification of impact loads, which is crucial for introducing the optimum real-time strategy of adaptive impact absorption. This paper presents the concept of an impactometer and develops the methodology able to perform real-time impact load identification. Considered dynamic excitation is generated by a mass M1 impacting with initial velocity V0. An analytical formulation of the problem, supported with numerical simulations and experimental verifications is presented. Two identification algorithms based on measured response of the impacted structure are proposed and discussed. Finally, a concept of the AIA device utilizing the idea of impactometer is briefly presented.

  2. On-line catalytic upgrading of biomass fast pyrolysis products

    Institute of Scientific and Technical Information of China (English)

    LU Qiang; ZHU XiFeng; LI WenZhi; ZHANG Ying; CHEN DengYu

    2009-01-01

    Pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) was employed to achieve fast pyrolysis of biomass and on-line analysis of the pyrolysis vapors. Four biomass materials (poplar wood, fir wood, cotton straw and rice husk) were pyrolyzed to reveal the difference among their products. Moreover, catalytic cracking of the pyrolysis vapors from cotton straw was performed by using five catalysts, including two microporous zeolites (HZSM-5 and HY) and three mesoporous catalysts (ZrO2&TiO2, SBA-15 and AI/SBA-15). The results showed that the distribution of the pyrolytic products from the four materials differed a little from each other, while catalytic cracking could significantly alter the pyrolytic products. Those important primary pyrolytic products such as levoglucosen, hydroxyacetaldehyde and 1-hydroxy-2-propanone were decreased greatly after catalysis. The two microporous zeolites were ef-fective to generate high yields of hydrocarbons, while the three mesoporous materials favored the formation of furan, furfural and other furan compounds, as well as acetic acid.

  3. On-line methods for rotorcraft aeroelastic mode identification

    Science.gov (United States)

    Molusis, J. A.; Kleinman, D. L.

    1982-01-01

    The requirements for the on-line identification of rotorcraft aeroelastic blade modes from random response test data are presented. A recursive maximum likelihood (RML) technique is used in conjunction with a bandpass filter to identify isolated blade mode damping and frequency. The RML technique is demonstrated to have excellent convergence characteristics in random measurement noise and random process noise excitation. The RML identification technique uses an ARMA representation for the aeroelastic stochastic system and requires virtually no user interaction while providing accurate confidence bands on the parameter estimates. Comparisons are made with an off-line Newton type maximum likelihood algorithm which uses a state variable model representation. Results are presented from simulation random response data which quantify the identifed parameter convergence behavior for various levels of random excitation which is typical of wind tunnel turbulence levels. The RML technique is applied to hingless rotor test data from the NASA Langley Research Center Helicopter Hover Facility.

  4. On-Line Fast Motor Fault Diagnostics Based on Fuzzy Neural Networks

    Institute of Scientific and Technical Information of China (English)

    DONG Mingchui; CHEANG Takson; CHAN Sileong

    2009-01-01

    An on-line method was developed to improve diagnostic accuracy and speed for analyzing run-ning motors on site. On-line pre-measured data was used as the basis for constructing the membership functions used in a fuzzy neural network (FNN) as well as for network training to reduce the effects of vari-ous static factors, such as unbalanced input power and asymmetrical motor alignment, to increase accuracy.The preprocessed data and fuzzy logic were used to find the nonlinear mapping relationships between the data and the conclusions. The FNN was then constructed to carry motor fault diagnostics, which gives fast accurate diagnostics. The on-line fast motor fault diagnostics clearly indicate the fault type, location, and severity in running motors. This approach can also be extended to other applications.

  5. On-line Identification of the DC motor Parameters by using Least Mean Square Recursive Method

    Directory of Open Access Journals (Sweden)

    Marian Gaiceanu

    2014-09-01

    Full Text Available The on-line least square parameters (electrical and mechanical identification method of the separately DC motor is presented in this paper. The parameters of the DC machine are time dependent; therefore, for the DC drive control the on-line parameters identification procedure is mandatory. By knowing accurately the DC motor parameters, the parameters of the DC speed and current cascade controllers can be obtained.

  6. Integrated Health Monitoring and Fast on-Line Actuator Reconfiguration Enhancement (IHM-FLARE) System for Air Vehicles Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SSCI proposes to develop innovative algorithms for the integration of Health Monitoring (HM) subsystem with the existing FLARE (Fast on-Line Actuator Reconfiguration...

  7. On-line identification of hybrid systems using an adaptive growing and pruning RBF neural network

    DEFF Research Database (Denmark)

    Alizadeh, Tohid

    2008-01-01

    This paper introduces an adaptive growing and pruning radial basis function (GAP-RBF) neural network for on-line identification of hybrid systems. The main idea is to identify a global nonlinear model that can predict the continuous outputs of hybrid systems. In the proposed approach, GAP......-RBF neural network uses a modified unscented kalman filter (UKF) with forgetting factor scheme as the required on-line learning algorithm. The effectiveness of the resulting identification approach is tested and evaluated on a simulated benchmark hybrid system....

  8. On-line detecting of transformer winding deformation based on parameter identification of leakage inductance

    Institute of Scientific and Technical Information of China (English)

    Hao Zhiguo; Zhang Baohui; Li Peng

    2007-01-01

    Transformers are required to demonstrate the ability to withstand short circuit currents. Over currents caused by short circuit can give rise to windings deformation. In this paper, a novel method is proposed to monitor the state of transformer windings, which is achieved through on-line detecting the leakage inductance of the windings. Specifically, the mathematical model is established for on-line identifying the leakage inductance of the windings by applying least square algorithm (LSA) to the equivalent circuit equations. The effect of measurement and model inaccuracy on the identification error is analyzed, and the corrected model is also given to decrease these adverse effect on the results. Finally, dynamic test is carried out to verify our method. The test results clearly show that our method is very accurate even under the fluctuation of load or power factor. Therefore, our method can be effectively used to on-line detect the windings deformation.

  9. Silicon Drift Detector Readout and ON-LINE Data Reduction using a Fast VLSI Dedicated Fuzzy Proccessor

    CERN Document Server

    Petta, C; CERN. Geneva; Randazzo, N; Russo, M

    1995-01-01

    A Silicon Drift Detector Front-End and a Smart Readout System different from a trivial zero-suppression is proposed. ON-LINE pre-processing, using a Fast VSLI dedicated Fuzzy Processor, reduces significantly acquisition data volume and hardware requirements..

  10. Semi-on-line analysis for fast and precise monitoring of bioreaction processes

    DEFF Research Database (Denmark)

    Christensen, L.H.; Marcher, J.; Schulze, Ulrik

    1996-01-01

    Monitoring of substrates and products during fermentation processes can be achieved either by on-line, in situ sensors or by semi-on-line analysis consisting of an automatic sampling step followed by an ex situ analysis of the retrieved sample. The potential risk of introducing time delays...... and signal bias during sampling makes it necessary to distinguish between real-time, on-line, in situ methods and semi-on-line analysis. In addition, semi-on-line analyzers are often mechanically complex-a circumstance which has to be given special attention during their industrial use on a routine basis....... This review on semi-on-line analysis will focus both on the dynamics and precision of aseptic sampling devices and on the performance of flow injection analysis (FIA) and sequential injection analysis (SIA), especially with regard to their robustness when used in industry. (C) 1996 John Wiley & Sons, Inc....

  11. Time-Varying FOPDT Modeling and On-line Parameter Identification

    DEFF Research Database (Denmark)

    Yang, Zhenyu; Sun, Zhen

    2013-01-01

    A type of Time-Varying First-Order Plus Dead-Time (TV-FOPDT) model is extended from SISO format into a MISO version by explicitly taking the disturbance input into consideration. Correspondingly, a set of on-line parameter identification algorithms oriented to MISO TV-FOPDT model are proposed bas...... are firstly illustrated through a numerical example, and then applied to investigate transient superheat dynamic modeling in a supermarket refrigeration system....... on the Mixed-Integer-Nonlinear Programming, Least-Mean-Square and sliding window techniques. The proposed approaches can simultaneously estimate the time-dependent system parameters, as well as the unknown disturbance input if it is the case, in an on-line manner. The proposed concepts and algorithms...

  12. Practical Damping Identification of FAST Cable Suspension

    Directory of Open Access Journals (Sweden)

    Jinghai Sun

    2014-03-01

    Full Text Available FAST focus cabin is suspended and driven by 6 parallel large span cables. Low stiffness of cables makes the cabin sensitive to disturbance and difficult to control. Structural damping then becomes a key factor that can improve control ability. Therefore, a reasonable damping estimation is important for system design. In this paper, a practical damping identification method is developed based on Ibrahim-time-domain algorithm. The method shows satisfied performance on accuracy and reliability in simulation test and is utilized in vibration experiments to identify damping ratios of both single cable model and FAST 3 m scale cable suspension model. Finally, a preliminary analysis of the damping properties is given out based on the results of identification.

  13. Investigation of the stochastic subspace identification method for on-line wind turbine tower monitoring

    Science.gov (United States)

    Dai, Kaoshan; Wang, Ying; Lu, Wensheng; Ren, Xiaosong; Huang, Zhenhua

    2017-04-01

    Structural health monitoring (SHM) of wind turbines has been applied in the wind energy industry to obtain their real-time vibration parameters and to ensure their optimum performance. For SHM, the accuracy of its results and the efficiency of its measurement methodology and data processing algorithm are the two major concerns. Selection of proper measurement parameters could improve such accuracy and efficiency. The Stochastic Subspace Identification (SSI) is a widely used data processing algorithm for SHM. This research discussed the accuracy and efficiency of SHM using SSI method to identify vibration parameters of on-line wind turbine towers. Proper measurement parameters, such as optimum measurement duration, are recommended.

  14. Vehicle dynamic prediction systems with on-line identification of vehicle parameters and road conditions.

    Science.gov (United States)

    Hsu, Ling-Yuan; Chen, Tsung-Lin

    2012-01-01

    This paper presents a vehicle dynamics prediction system, which consists of a sensor fusion system and a vehicle parameter identification system. This sensor fusion system can obtain the six degree-of-freedom vehicle dynamics and two road angles without using a vehicle model. The vehicle parameter identification system uses the vehicle dynamics from the sensor fusion system to identify ten vehicle parameters in real time, including vehicle mass, moment of inertial, and road friction coefficients. With above two systems, the future vehicle dynamics is predicted by using a vehicle dynamics model, obtained from the parameter identification system, to propagate with time the current vehicle state values, obtained from the sensor fusion system. Comparing with most existing literatures in this field, the proposed approach improves the prediction accuracy both by incorporating more vehicle dynamics to the prediction system and by on-line identification to minimize the vehicle modeling errors. Simulation results show that the proposed method successfully predicts the vehicle dynamics in a left-hand turn event and a rollover event. The prediction inaccuracy is 0.51% in a left-hand turn event and 27.3% in a rollover event.

  15. A neural network device for on-line particle identification in cosmic ray experiments

    Energy Technology Data Exchange (ETDEWEB)

    Scrimaglio, R. E-mail: renato.scrimaglio@aquila.infn.it; Finetti, N.; D' Altorio, L.; Rantucci, E.; Raso, M.; Segreto, E.; Tassoni, A.; Cardarilli, G.C

    2004-05-21

    On-line particle identification is one of the main goals of many experiments in space both for rare event studies and for optimizing measurements along the orbital trajectory. Neural networks can be a useful tool for signal processing and real time data analysis in such experiments. In this document we report on the performances of a programmable neural device which was developed in VLSI analog/digital technology. Neurons and synapses were accomplished by making use of Operational Transconductance Amplifier (OTA) structures. In this paper we report on the results of measurements performed in order to verify the agreement of the characteristic curves of each elementary cell with simulations and on the device performances obtained by implementing simple neural structures on the VLSI chip. A feed-forward neural network (Multi-Layer Perceptron, MLP) was implemented on the VLSI chip and trained to identify particles by processing the signals of two-dimensional position-sensitive Si detectors. The radiation monitoring device consisted of three double-sided silicon strip detectors. From the analysis of a set of simulated data it was found that the MLP implemented on the neural device gave results comparable with those obtained with the standard method of analysis confirming that the implemented neural network could be employed for real time particle identification.

  16. XOP: a second generation fast processor for on-line use in high energy physics experiments

    CERN Document Server

    Lingjaerde, Tor

    1981-01-01

    Processors for trigger calculations and data compression in high energy physics are characterized by a high data input capability combined with fast execution of relatively simple routines. In order to achieve the required performance it is advantageous to replace the classical computer instruction-set by microcoded instructions, the various fields of which control the internal subunits in parallel. The fast processor called ESOP is based on such a principle: the different operations are handled step by step by dedicated optimized modules under control of a central instruction unit. Thus, the arithmetic operations, address calculations, conditional checking, loop counts and next instruction evaluation all overlap in time. Based upon the experience from ESOP the architecture of a new processor "XOP" is beginning to take shape which will be faster and easier to use. In this context the most important innovations are: easy handling of operands in the arithmetic unit by means of three data buses and large data fi...

  17. A fast-initializing digital equalizer with on-line tracking for data communications

    Science.gov (United States)

    Houts, R. C.; Barksdale, W. J.

    1974-01-01

    A theory is developed for a digital equalizer for use in reducing intersymbol interference (ISI) on high speed data communications channels. The equalizer is initialized with a single isolated transmitter pulse, provided the signal-to-noise ratio (SNR) is not unusually low, then switches to a decision directed, on-line mode of operation that allows tracking of channel variations. Conditions for optimal tap-gain settings are obtained first for a transversal equalizer structure by using a mean squared error (MSE) criterion, a first order gradient algorithm to determine the adjustable equalizer tap-gains, and a sequence of isolated initializing pulses. Since the rate of tap-gain convergence depends on the eigenvalues of a channel output correlation matrix, convergence can be improved by making a linear transformation on to obtain a new correlation matrix.

  18. Multiple concurrent recursive least squares identification with application to on-line spacecraft mass-property identification

    Science.gov (United States)

    Wilson, Edward (Inventor)

    2006-01-01

    The present invention is a method for identifying unknown parameters in a system having a set of governing equations describing its behavior that cannot be put into regression form with the unknown parameters linearly represented. In this method, the vector of unknown parameters is segmented into a plurality of groups where each individual group of unknown parameters may be isolated linearly by manipulation of said equations. Multiple concurrent and independent recursive least squares identification of each said group run, treating other unknown parameters appearing in their regression equation as if they were known perfectly, with said values provided by recursive least squares estimation from the other groups, thereby enabling the use of fast, compact, efficient linear algorithms to solve problems that would otherwise require nonlinear solution approaches. This invention is presented with application to identification of mass and thruster properties for a thruster-controlled spacecraft.

  19. Implementation of a neural network for digital pulse shape analysis on a FPGA for on-line identification of heavy ions

    Science.gov (United States)

    Jiménez, R.; Sánchez-Raya, M.; Gómez-Galán, J. A.; Flores, J. L.; Dueñas, J. A.; Martel, I.

    2012-05-01

    Pulse shape analysis techniques for the identification of heavy ions produced in nuclear reactions have been recently proposed as an alternative to energy loss and time of flight methods. However this technique requires a large amount of memory for storing the shapes of charge and current signals. We have implemented a hardware solution for fast on-line processing of the signals producing the relevant information needed for particle identification. Since the pulse shape analysis can be formulated in terms of a pattern recognition problem, a neural network has been implemented in a FPGA device. The design concept has been tested using 12,13C ions produced in heavy ion reactions. The actual latency of the system is about 20 μs when using a clock frequency of 50 MHz.

  20. Implementation of a neural network for digital pulse shape analysis on a FPGA for on-line identification of heavy ions

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, R., E-mail: naharro@uhu.es [Departamento de Ingenieria Eletronica, Sistemas Informaticos y Automatica, Universidad de Huelva, 21071 Huelva (Spain); Sanchez-Raya, M.; Gomez-Galan, J.A. [Departamento de Ingenieria Eletronica, Sistemas Informaticos y Automatica, Universidad de Huelva, 21071 Huelva (Spain); Flores, J.L. [Departamento Ingenieria Electrica y Termica, Universidad de Huelva, 21071 Huelva (Spain); Duenas, J.A.; Martel, I. [Departamento de Fisica Aplicada, Universidad de Huelva, 21071 Huelva (Spain)

    2012-05-11

    Pulse shape analysis techniques for the identification of heavy ions produced in nuclear reactions have been recently proposed as an alternative to energy loss and time of flight methods. However this technique requires a large amount of memory for storing the shapes of charge and current signals. We have implemented a hardware solution for fast on-line processing of the signals producing the relevant information needed for particle identification. Since the pulse shape analysis can be formulated in terms of a pattern recognition problem, a neural network has been implemented in a FPGA device. The design concept has been tested using {sup 12,13}C ions produced in heavy ion reactions. The actual latency of the system is about 20 {mu}s when using a clock frequency of 50 MHz.

  1. Process Identification in On-line Optimizing Control, an Application to a Heat Pump

    Directory of Open Access Journals (Sweden)

    Morten C. Svensson

    1996-10-01

    Full Text Available The objective of this paper is to focus on on-line state and parameter estimation in connection with on-line model-based optimizing control of continuous processes. A nonlinear programming approach is used to estimate unmeasured state variables and parameters in systems modelled by nonlinear differential-algebraic equations. The nonlinear dynamic model is discretized by orthogonal collocation on finite elements, and the moving-horizon approach is used to reduce the dimension of the final optimization problem.

  2. Pitch Correlogram Clustering for Fast Speaker Identification

    Directory of Open Access Journals (Sweden)

    Nitin Jhanwar

    2004-12-01

    Full Text Available Gaussian mixture models (GMMs are commonly used in text-independent speaker identification systems. However, for large speaker databases, their high computational run-time limits their use in online or real-time speaker identification situations. Two-stage identification systems, in which the database is partitioned into clusters based on some proximity criteria and only a single-cluster GMM is run in every test, have been suggested in literature to speed up the identification process. However, most clustering algorithms used have shown limited success, apparently because the clustering and GMM feature spaces used are derived from similar speech characteristics. This paper presents a new clustering approach based on the concept of a pitch correlogram that captures frame-to-frame pitch variations of a speaker rather than short-time spectral characteristics like cepstral coefficient, spectral slopes, and so forth. The effectiveness of this two-stage identification process is demonstrated on the IVIE corpus of 110 speakers. The overall system achieves a run-time advantage of 500% as well as a 10% reduction of error in overall speaker identification.

  3. Vehicle Dynamic Prediction Systems with On-Line Identification of Vehicle Parameters and Road Conditions

    OpenAIRE

    Ling-Yuan Hsu; Tsung-Lin Chen

    2012-01-01

    This paper presents a vehicle dynamics prediction system, which consists of a sensor fusion system and a vehicle parameter identification system. This sensor fusion system can obtain the six degree-of-freedom vehicle dynamics and two road angles without using a vehicle model. The vehicle parameter identification system uses the vehicle dynamics from the sensor fusion system to identify ten vehicle parameters in real time, including vehicle mass, moment of inertial, and road friction coefficie...

  4. Towards the On-line Identification of Peer-to-peer Flow Patterns

    Directory of Open Access Journals (Sweden)

    Antonio Nogueira

    2009-04-01

    Full Text Available The number and variety of IP applications have hugely increased in the last few years. Among them, peer-to-peer (P2P file-sharing applications have become very popular: more users are continuously joining such systems and more objects are being made available, seducing even more users to join. An accurate mapping of traffic to applications is important for a wide range of network management tasks. Besides, traditional mapping approaches have become increasingly inaccurate because many applications use non-default or ephemeral port numbers, use well-known port numbers associated with other applications, change application signatures or use traffic encryption. This paper proposes a framework to identify Internet applications that can be mainly used in situations where existing identification frameworks are not efficient or can not be used at all. The core block of the identification tool is based on neural networks and is able to identify different flow patterns generated by various Internet applications. Neural network based identification relies on a previous identification of the different IP applications that can be obtained offline using any reliable method. In this way, the paper also presents a module to process IP traffic flows and identify the underlying applications using payload analysis techniques. The identification results obtained from this tool are used in the training phase of the neural network identification framework. The accuracy of the identification framework was evaluated by performing a set of intensive tests and the results obtained show that, when conveniently trained, neural networks constitute a valuable tool to identify Internet applications while being, at the same time, immune to the most important disadvantages presented by other identification methods.

  5. On line power spectra identification and whitening for the noise in interferometric gravitational wave detectors

    CERN Document Server

    Cuoco, E; Fabbroni, L; Losurdo, G; Mazzoni, M; Stanga, R M; Vetrano, F

    2001-01-01

    In this paper we address both to the problem of identifying the noise Power Spectral Density of interferometric detectors by parametric techniques and to the problem of the whitening procedure of the sequence of data. We will concentrate the study on a Power Spectral Density like the one of the Italian-French detector VIRGO and we show that with a reasonable finite number of parameters we succeed in modeling a spectrum like the theoretical one of VIRGO, reproducing all its features. We propose also the use of adaptive techniques to identify and to whiten on line the data of interferometric detectors. We analyze the behavior of the adaptive techniques in the field of stochastic gradient and in the Least Squares ones.

  6. On-line identification, flutter testing and adaptive notching of structural parameters for V-22 tiltrotor aircraft

    Indian Academy of Sciences (India)

    R K Mehra; P O Arambel; A M Sampath; R K Prasanth; T C Parham

    2000-04-01

    New algorithms and results are presented for flutter testing and adaptive notching of structural modes in V-22 tiltrotor aircraft based on simulated and flight-test data from Bell Helicopter Textron, Inc. (BHTI). For flutter testing and the identification of structural mode frequencies, dampings and mode shapes, time domain state space techniques based on Deterministic Stochastic Realization Algorithms (DSRA) are used to accurately identify multiple modessimultaneously from sine sweep and other multifrequency data, resulting in great savings over the conventional Prony method. Two different techniques for adaptive notching are explored in order to design an Integrated Flight Structural Control (IFSC) system. The first technique is based on on-line identification of structural mode parameters using DSRA algorithm and tuning of a notch filter. The second technique is based on decoupling rigid-body and structural modes of the aircraft by means of a Kalman filter and using rigid-body estimates in the feedback control loop. The difference between the two approaches is that on-line identification and adaptive notching in the first approach are entirely based on the knowledge of structural modes, whereas the Kalman filter design in the second approach is based on the rigid-body dynamic model only.In the first IFSC design, on-line identification is necessary for flight envelope expansion and to adjust the notch filter frequencies and suppress aero-servoelastic instabilities due to changing flight conditionssuch as gross weight, sling loads, and airspeed. It isshown that by tuning the notch filterfrequency to the identified frequency, the phase lag is reduced and the corresponding structural mode is effectively suppressed and stability is maintained. In the second IFSC design using Kalman filter design, the structural modes are again effectively suppressed. Furthermore, the rigid-body estimates are found to be fairly insensitive to both natural frequency and damping factor

  7. 一种快速在线图形识别与规整化方法%A Method of Fast On-Line Graphics Recognition and Regularization

    Institute of Scientific and Technical Information of China (English)

    孙建勇; 金翔宇; 彭彬彬; 孙正兴; 刘文印

    2003-01-01

    A novel and fast shape classification and regularization algorithm for on-line sketchy graphics recognition is proposed. We divide the on-line graphics recognition process into four stages: preprocessing,shape classification,shape fitting,and regularization. Attraction Force Model is employed to progressively combine the vertices on the input sketchy stroke and reduce the total number of vertices before the type of shape can be determined. After that ,the shape is fitted and gradually rectified to a regular one,thus the regularized shape fits the user intended one precisely.Experimental results show that this algorithm can yield good recognition precision(averagely above 90% )and fine regularization effect but with fast speed. Consequently,it is especially suitable to computational critical environment such as PDAs,which solely depends on a pen-based user interface.

  8. Fast LIBS Identification of Aluminum Alloys

    Directory of Open Access Journals (Sweden)

    Tawfik W.

    2007-04-01

    Full Text Available Laser-induced breakdown spectroscopy (LIBS has been applied to analysis aluminum alloy targets. The plasma is generated by focusing a 300 mJ pulsed Nd: YAG laser on the target in air at atmospheric pressure. Such plasma emission spectrum was collected using a one-meter length wide band fused-silica optical fiber connected to a portable Echelle spectrometer with intensified CCD camera. Spectroscopic analysis of plasma evolution of laser produced plasmas has been characterized in terms of their spectra, electron density and electron temperature assuming the LTE and optically thin plasma conditions. The LIBS spectrum was optimized for high S/N ratio especially for trace elements. The electron temperature and density were determined using the emission intensity and stark broadening, respectively, of selected aluminum spectral lines. The values of these parameters were found to change with the aluminum alloy matrix, i.e. they could be used as a fingerprint character to distinguish between different aluminum alloy matrices using only one major element (aluminum without needing to analysis the rest of elements in the matrix. Moreover, It was found that the values of T(e and N(e decrease with increasing the trace elements concentrations in the aluminum alloy samples. The obtained results indicate that it is possible to improve the exploitation of LIBS in the remote on-line industrial monitoring application, by following up only the values of T(e and N(e for the aluminum in aluminum alloys using an optical fiber probe.

  9. Fast LIBS Identification of Aluminum Alloys

    Directory of Open Access Journals (Sweden)

    Tawfik W.

    2007-04-01

    Full Text Available Laser-induced breakdown spectroscopy (LIBS has been applied to analysis aluminum alloy targets. The plasma is generated by focusing a 300 mJ pulsed Nd: YAG laser on the target in air at atmospheric pressure. Such plasma emission spectrum was collected using a one-meter length wide band fused-silica optical fiber connected to a portable Echelle spectrometer with intensified CCD camera. Spectroscopic analysis of plasma evolution of laser produced plasmas has been characterized in terms of their spectra, electron density and electron temperature assuming the LTE and optically thin plasma conditions. The LIBS spectrum was optimized for high S/N ratio especially for trace elements. The electron temperature and density were determined using the emission intensity and stark broadening, respectively, of selected aluminum spectral lines. The values of these parameters were found to change with the aluminum alloy matrix, i.e. they could be used as a fingerprint character to distinguish between different aluminum alloy matrices using only one major element (aluminum without needing to analysis the rest of elements in the matrix. Moreover, It was found that the values of T e and N e decrease with increasing the trace elements concentrations in the aluminum alloy samples. The obtained results indicate that it is possible to improve the exploitation of LIBS in the remote on-line industrial monitoring application, by following up only the values of T e and N e for aluminum in aluminum alloys as a marker for the correct alloying using an optical fiber probe.

  10. On-Line Screening, Isolation and Identification of Antioxidant Compounds of Helianthemum ruficomum

    Directory of Open Access Journals (Sweden)

    Yasmine Chemam

    2017-02-01

    Full Text Available Many Helianthemum species (Cistaceae are recognized for their various medicinal virtues. Helianthemum ruficomum is an endemic species to the septentrional Sahara on which no report is available so far. The purpose of this work was to investigate the chemical composition and the radical scavenging capacity of this species and its isolated components. Collected from Mougheul (south-west of Algeria, the aerial parts were macerated with 80% EtOH/H2O, after evaporation, the remaining extract was diluted with H2O and extracted with petroleum ether, chloroform, ethyl acetate and n-butanol. EtOAc and n-BuOH extracts were evaluated for their free radical scavenging capacity by on-line HPLC-ABTS•+ assay. The obtained data which were confirmed by TEAC and ORAC assays, allowed guiding the fractionation of these extracts by CC, TLC and reverse phase HPLC. Among the components, 14 were isolated and identified by spectroscopic analyses: protocatechuic acid (1, trans-tiliroside (2, cis-tiliroside (3, astragalin (4, picein (7, vanillic acid 4-O-β-d-glucopyranoside (8, lavandoside (9, 4-hydroxybenzoic acid 4-O-β-d-glucopyranoside (10, nicotiflorin (11, rutin (12, vicenin-2 (13, narcissin (14 and stigmasterol (5 and β-sitosterol (6 as a mixture (71% and 29%, respectively. Compounds 5, 7, 8, 9, 10 and 14 were new for the genus Helianthemum. The antioxidant power of all the isolated compounds was also evaluated by HPLC-ABTS•+, TEAC and ORAC assays. The results clearly indicated high antioxidant potential of the extracts and tested compounds of this species especially, compounds 1, 4, 8, 9, 10 and 12.

  11. High resolution, on-line identification of strains from the Mycobacterium tuberculosis complex based on tandem repeat typing

    Directory of Open Access Journals (Sweden)

    Denoeud France

    2002-11-01

    Full Text Available Abstract Background Currently available reference methods for the molecular epidemiology of the Mycobacterium tuberculosis complex either lack sensitivity or are still too tedious and slow for routine application. Recently, tandem repeat typing has emerged as a potential alternative. This report contributes to the development of tandem repeat typing for M. tuberculosis by summarising the existing data, developing additional markers, and setting up a freely accessible, fast, and easy to use, internet-based service for strain identification. Results A collection of 21 VNTRs incorporating 13 previously described loci and 8 newly evaluated markers was used to genotype 90 strains from the M. tuberculosis complex (M. tuberculosis (64 strains, M. bovis (9 strains including 4 BCG representatives, M. africanum (17 strains. Eighty-four different genotypes are defined. Clustering analysis shows that the M. africanum strains fall into three main groups, one of which is closer to the M. tuberculosis strains, and an other one is closer to the M. bovis strains. The resulting data has been made freely accessible over the internet http://bacterial-genotyping.igmors.u-psud.fr/bnserver to allow direct strain identification queries. Conclusions Tandem-repeat typing is a PCR-based assay which may prove to be a powerful complement to the existing epidemiological tools for the M. tuberculosis complex. The number of markers to type depends on the identification precision which is required, so that identification can be achieved quickly at low cost in terms of consumables, technical expertise and equipment.

  12. On-line coupling of physiologically relevant bioaccessibility testing to inductively coupled plasma spectrometry: Proof of concept for fast assessment of gastrointestinal bioaccessibility of micronutrients from soybeans.

    Science.gov (United States)

    Herrera, Mónica Alejandra; Rosende, María; Arruda, Marco Aurélio Zezzi; Miró, Manuel

    2016-10-05

    In-vitro physiologically relevant gastrointestinal extraction based on the validated Unified BARGE Method (UBM) is in this work hyphenated to inductively coupled plasma optical emission spectrometry in a batch-flow configuration for real-time monitoring of oral bioaccessibility assays with high temporal resolution. A fully automated flow analyzer is designed to foster in-line filtration of gastrointestinal extracts at predefined times (≤15 min) followed by on-line multi-elemental analysis of bioaccessible micro-nutrients, viz., Cu, Fe and Mn, in well-defined volumes of extracts (300 μL) of transgenic and non-transgenic soybean seeds taken as model samples. The hyphenated flow setup allows for recording of temporal extraction profiles to gain full knowledge of the kinetics of the gastrointestinal digestion processes, including element leaching and concomitant precipitation and complexation reactions hindering bioavailability. Simplification of the overall standard procedure is also feasible by identification of steady-state extraction conditions. Our findings indicate that reliable measurement of oral bioaccessible pools of Cu, Fe and Mn in soybean might be obtained in less than 180 min rather than 240 min as endorsed by UBM. Using a matrix-matched external calibration, limits of detection according to the 3s criteria were 0.5 μg/g for Mn, 0.6 μg/g for Cu and 2.3 μg/g for Fe. Trueness of the automatic bioaccessibility method was confirmed by mass balance validation with recoveries ranging from 87 to 116% regardless of the target element and sample. Cu was the micronutrient with the highest oral bioaccessibility ranging from 73% to 83% (7.5-7.9 μg/g) for non-transgenic and transgenic soybeans, respectively, followed by Mn and Fe within the ranges of 29-31% (10.8-11.4 μg/g) and 11-15% (8-14 μg/g), respectively, regardless of transgenesis. The proposed kinetic method is proven suitable for fast and expedient estimation of the nutritional value of

  13. On-line Identification of chiral ofloxacin in milk with an extraction/ionization device coupled to Electrospray Mass Spectrometry.

    Science.gov (United States)

    Wang, Jiang; Jiang, Xiao-Xiao; Zhao, Wei; Hu, Jun; Guan, Qi-Yuan; Xu, Jing-Juan; Chen, Hong-Yuan

    2017-08-15

    The direct separation and analysis of chiral drugs in the complex matrix systems are meaningful and challenging. As the most common broad-spectrum antibiotic, levofloxacin has a strong antibacterial ability, but its enantiomer, dextrofloxacin can cause serious harm to human health. In this work, we reported a rapid on-line extraction/ionization device coupled with Electrospray Mass Spectrometry (ESI-MS) for chiral analysis of ofloxacin enantiomers in complex matrix of milk. Since ofloxacin is difficult to dissolve in water and most organic solvents, the procedure of separating ofloxacin in complex system is often complicated. Using the homemade apparatus, the sample pretreatment process was greatly simplified. Milk sample was directly injected and chiral ofloxacin in the sample was extracted at PTFE membrane for further ionization. It took less than 10s to finish all the procedures including sampling, extraction, reagents mixing, ionization and mass analysis. Utilizing reaction thermodynamics method, trimeric cluster ion [Ni(ΙΙ)(ref)2Ofloxacin-H](+) was formed and collisionally dissociated to get chiral resolution of levofloxacin and dextrofloxacin due to the different relative stabilities of the two diastereomeric clusters produced through the dissociation of Ni(ΙΙ) bound trimeric clusters. With the proposed method, qualitative and quantitative chiral analysis of ofloxacin in milk was successfully achieved in a simple and fast way. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Fast and automatic thermographic material identification for the recycling process

    Science.gov (United States)

    Haferkamp, Heinz; Burmester, Ingo

    1998-03-01

    Within the framework of the future closed loop recycling process the automatic and economical sorting of plastics is a decisive element. The at the present time available identification and sorting systems are not yet suitable for the sorting of technical plastics since essential demands, as the realization of high recognition reliability and identification rates considering the variety of technical plastics, can not be guaranteed. Therefore the Laser Zentrum Hannover e.V. in cooperation with the Hoerotron GmbH and the Preussag Noell GmbH has carried out investigations on a rapid thermographic and laser-supported material- identification-system for automatic material-sorting- systems. The automatic identification of different engineering plastics coming from electronic or automotive waste is possible. Identification rates up to 10 parts per second are allowed by the effort from fast IR line scanners. The procedure is based on the following principle: within a few milliseconds a spot on the relevant sample is heated by a CO2 laser. The samples different and specific chemical and physical material properties cause different temperature distributions on their surfaces that are measured by a fast IR-linescan system. This 'thermal impulse response' has to be analyzed by means of a computer system. Investigations have shown that it is possible to analyze more than 18 different sorts of plastics at a frequency of 10 Hz. Crucial for the development of such a system is the rapid processing of imaging data, the minimization of interferences caused by oscillating samples geometries, and a wide range of possible additives in plastics in question. One possible application area is sorting of plastics coming from car- and electronic waste recycling.

  15. SIDOL – Sistema de Identificação Dendrológica On-line / SIDOL - On-line Dendrologic Identification System

    Directory of Open Access Journals (Sweden)

    Daniel Saueressig

    2009-04-01

    Full Text Available ResumoApresenta-se um sistema informatizado, com uso via Internet, objetivando facilitar e agilizar o processo de identificação das espécies arbóreas e principais arbustos encontrados no Campus Universitário de Irati (UNICENTRO, que tem como base a combinação de características macromorfológicas informadas pelo usuário. O sistema de consulta, apresentado em modo formulário, é dinâmico. Os passos do usuário são guiados e as ações informadas, facilitando o entendimento e a interação com o sistema. Após a entrada das informações, o sistema consulta as tabelas do banco de dados em busca de resultados. Os resultados da busca, caso haja registro, são exibidas ao usuário, que não precisa ter conhecimento técnico para operar o sistema. Associado à criação do sistema foi realizado o estudo florístico do Campus, que mostrou a presença de 127 espécies pertencentes a 92 gêneros e 46 famílias. As famílias Myrtaceae (19 espécies, Fabaceae (15, Lauraceae (9, Asteraceae (7, Salicaceae (6 e Aquifoliaceae, Euphorbiaceae, Rosaceae e Solanaceae (5, apresentaram uma maior riqueza florística e juntas representam 59,84% das espécies catalogadas. Os gêneros mais ricos foram Ilex (5 espécies, Eugenia e Casearia (4 e Cinnamomum, Zanthoxylum, Ocotea e Myrcia (3.AbstractA virtual system supported by Internet is presented in order to facilitate and accelerate identification of trees and shrubs growing at the University Campus in Irati, Paraná State, Brazil (UNICENTRO - Universidade Estadual do Centro-Oeste. The system key is the combination of macromorphological characteristics informed by the user. The search system is dynamic and is presented in a chart format. User steps are guided and actions are informed in order to facilitate understanding and interaction with the system. After the information input, the system searches results in the data bank. When the input matches an existing record, the system displays the stored

  16. Identification of Variables and Factors Impacting Consumer Behavior in On-line Shopping in India: An Empirical Study

    Science.gov (United States)

    Chhikara, Sudesh

    On-line shopping is a recent phenomenon in the field of E-Business and is definitely going to be the future of shopping in the world. Most of the companies are running their on-line portals to sell their products/services. Though online shopping is very common outside India, its growth in Indian Market, which is a large and strategic consumer market, is still not in line with the global market. The potential growth of on-line shopping has triggered the idea of conducting a study on on-line shopping in India. The present research paper has used exploratory study to depict and highlight the various categories of factors and variables impacting the behavior of consumers towards on-line shopping in India. The data was collected through in-depth interviews on a sample of 41 respondents from Delhi, Mumbai, Chennai and Bangalore. The results of the study show that on-line shopping in India is basically impacted by five categories of factors like demographics factor, Psychographics factor, Online shopping feature and policies, Technological factor, Security factor. The results of the study are used to present a comprehensive model of on-line shopping which could be further used by the researchers and practitioners for conducting future studies in the similar area. A brief operational definition of all the factors and variables impacting on-line shopping in India is also described. And finally practical implications of the study are also elucidated.

  17. TU-F-CAMPUS-J-05: Fast Volumetric MRI On An MRI-Linac Enables On-Line QA On Dose Deposition in the Patient

    Energy Technology Data Exchange (ETDEWEB)

    Crijns, S; Glitzner, M; Kontaxis, C; Maenhout, M; Bol, G; Lagendijk, J; Raaymakers, B [University Medical Center Utrecht, Utrecht (Netherlands); Senneville, B Denis de [University Medical Center Utrecht, Utrecht (Netherlands); Mathematical Institute of Bordeaux, University of Bordeaux, Talence Cedex (France)

    2015-06-15

    Purpose: The introduction of the MRI-linac in radiotherapy brings MRI-guided treatment with daily plan adaptions within reach. This paradigm demands on-line QA. With its ability to perform continuous volumetric imaging in an outstanding soft-tissue contrast, the MRI- linac promises to elucidate the dose deposition process during a treatment session. Here we study for a prostate case how dynamic MRI combined with linac machine parameters and a fast dose-engine can be used for on-line dose accumulation. Methods: Prostate imaging was performed in healthy volunteer on a 1.5T MR-scanner (Philips, Best, NL) according to a clinical MR-sim protocol, followed by 10min of dynamic imaging (FLASH, 4s/volume, FOV 40×40×12cm{sup 3}, voxels 3×3×3mm{sup 3}, TR/TE/α=3.5ms/1.7ms/5°). An experienced radiation oncologist made delineations, considering the prostate CTV. Planning was performed on a two-compartment pseudoCT (air/water density) according to clinical constraints (77Gy in PTV) using a Monte-Carlo (MC) based TPS that accounts for magnetic fields. Delivery of one fraction (2.2Gy) was simulated on an emulator for the Axesse linac (Elekta, Stockholm, SE). Machine parameters (MLC settings, gantry angle, dose rate, etc.) were recorded at 25Hz. These were re-grouped per dynamic volume and fed into the MC-engine to calculate a dose delivered for each of the dynamics. Deformations derived from non-rigid registration of each dynamic against the first allowed dose accumulation on a common reference grid. Results: The DVH parameters on the PTV compared to the optimized plan showed little changes. Local deformations however resulted in local deviations, primarily around the air/rectum interface. This clearly indicates the potential of intra-fraction adaptations based on the accumulated dose. Application in each fraction helps to track the influence of plan adaptations to the eventual dose distribution. Calculation times were about twice the delivery time. Conclusion: The current

  18. A pipeline VLSI design of fast singular value decomposition processor for real-time EEG system based on on-line recursive independent component analysis.

    Science.gov (United States)

    Huang, Kuan-Ju; Shih, Wei-Yeh; Chang, Jui Chung; Feng, Chih Wei; Fang, Wai-Chi

    2013-01-01

    This paper presents a pipeline VLSI design of fast singular value decomposition (SVD) processor for real-time electroencephalography (EEG) system based on on-line recursive independent component analysis (ORICA). Since SVD is used frequently in computations of the real-time EEG system, a low-latency and high-accuracy SVD processor is essential. During the EEG system process, the proposed SVD processor aims to solve the diagonal, inverse and inverse square root matrices of the target matrices in real time. Generally, SVD requires a huge amount of computation in hardware implementation. Therefore, this work proposes a novel design concept for data flow updating to assist the pipeline VLSI implementation. The SVD processor can greatly improve the feasibility of real-time EEG system applications such as brain computer interfaces (BCIs). The proposed architecture is implemented using TSMC 90 nm CMOS technology. The sample rate of EEG raw data adopts 128 Hz. The core size of the SVD processor is 580×580 um(2), and the speed of operation frequency is 20MHz. It consumes 0.774mW of power during the 8-channel EEG system per execution time.

  19. Interfacing on-line solid phase extraction with monolithic column multisyringe chromatography and chemiluminescence detection: An effective tool for fast, sensitive and selective determination of thiazide diuretics.

    Science.gov (United States)

    Maya, Fernando; Estela, José Manuel; Cerdà, Víctor

    2010-01-15

    A new, multisyringe flow injection set-up has been developed for the completely automated determination of trace thiazide compounds with diuretic action in different types of samples. The proposed instrumental set-up exploits for the first time, a low pressure on-line solid phase extraction-liquid chromatography-chemiluminescence detection method. This novel combination of sample treatments in flow systems expands the current applicability of low pressure liquid chromatography due to the isolation/preconcentration of the target compounds, besides high selectivity and sensitivity. For the determination of three thiazide compounds named hydroflumethiazide, furosemide and bendroflumethiazide, the proposed set-up provided with the preconcentration of only 1mL of sample, limits of detection of 3, 60 and 40microgL(-1), respectively. Furthermore wide linear dynamic ranges of 6-4000, 140-20,000 and 90-40,000microgL(-1), respectively, were obtained. Besides of this, a high injection throughput of 12h(-1) was also achieved. As in sports, thiazide diuretics are prohibited substances, the proposed method has been applied to their determination in urine samples. Furthermore the potential of the proposed method as a fast-screening approach for emerging contaminants in waters has been also tested by applying it to well water and leachates from a solid waste landfill.

  20. Fast Photon Detection for Particle Identification with COMPASS RICH-1

    CERN Document Server

    Abbon, P; Angerer, H; Apollonio, M; Birsa, R; Bordalo, P; Bradamante, Franco; Bressan, A; Busso, L; Chiosso, M; Ciliberti, P; Colantoni, M L; Costa, S; Dalla Torre, S; Dafni, T; Delagnes, E; Deschamps, H; Díaz, V; Dibiase, N; Duic, V; Eyrich, W; Faso, D; Ferrero, A; Finger, M; Fischer, H; Gerassimov, S; Giorgi, M; Gobbo, B; Hagemann, R; Von Harrach, D; Heinsius, F H; Horikawa, S; Joosten, R; Ketzer, B; Königsmann, K C; Kolosov, V N; Konorov, I; Kramer, Daniel; Kunne, Fabienne; Lehmann, A; Levorato, S; Maggiora, A; Magnon, A; Mann, A; Martin, A; Menon, G; Mutter, A; Nahle, O; Nerling, F; Neyret, D; Pagano, P; Panebianco, S; Panzieri, D; Paul, S; Pesaro, G; Polak, J; Rebourgeard, P; Robinet, F; Rocco, E; Schiavon, Paolo; Schill, C; Schroder, W; Silva, L; Slunecka, M; Sozzi, F; Steiger, L; Sulc, M; Svec, M; Tessarotto, F; Teufel, A; Wollny, H; COMPASS RICH Upgrade Group

    2007-01-01

    Particle identification at high rates is an important challenge for many current and future high-energy physics experiments. The upgrade of the COMPASS RICH-1 detector requires a new technique for Cherenkov photon detection at count rates of several $10^6$ per channel in the central detector region, and a read-out system allowing for trigger rates of up to 100 kHz. To cope with these requirements, the photon detectors in the central region have been replaced with the detection system described in this paper. In the peripheral regions, the existing multi-wire proportional chambers with CsI photocathode are now read out via a new system employing APV pre-amplifiers and flash ADC chips. The new detection system consists of multi-anode photomultiplier tubes (MAPMT) and fast read-out electronics based on the MAD4 discriminator and the F1-TDC chip. The RICH-1 is in operation in its upgraded version for the 2006 CERN SPS run. We present the photon detection design, constructive aspects and the first Cherenkov light ...

  1. Identification of fast-steering mirror based on chicken swarm optimization algorithm

    Science.gov (United States)

    Ren, Wei; Deng, Chao; Zhang, Chao; Mao, Yao

    2017-06-01

    According to the transfer function identification method of fast steering mirror exists problems which estimate the initial value is complicated in the process of using, put forward using chicken swarm algorithm to simplify the identification operation, reducing the workload of identification. chicken swarm algorithm is a meta heuristic intelligent population algorithm, which shows global convergence is efficient in the identification experiment, and the convergence speed is fast. The convergence precision is also high. Especially there are many parameters are needed to identificate in the transfer function without considering the parameters estimation problem. Therefore, compared with the traditional identification methods, the proposed approach is more convenient, and greatly achieves the intelligent design of fast steering mirror control system in enginerring application, shorten time of controller designed.

  2. Identification of radiation-induced hydrocarbons in halibut, cod and prawns by on-line coupled LC-GC/MS technique; Identifizierung strahleninduzierter Kohlenwasserstoffe in Heilbutt, Kabeljau und Riesengarnele mit on-line gekoppelter LC-GC/MS-Technik

    Energy Technology Data Exchange (ETDEWEB)

    Spiegelberg, A.; Schulzki, G.; Boegl, K.W.; Schreiber, G.A. [Bundesinstitut fuer Gesundheitlichen Verbraucherschutz und Veterinaermedizin, Berlin (Germany). Fachbereich Chemie und Technologie der Lebensmittel und Bedarfsgegenstaende

    1997-10-01

    Radiation-induced hydrocarbons were analysed in a fatty (halibut) and a lean fish (cod) as well as in a prawn species by on-line coupled liquid chromatography (LC) - gas chromatography (GC) combined with mass spectrometrical detection. In irradiated halibut which contains mainly saturated and monounsaturated fatty acids all expected radiolytic alkanes, alkenes and alkadienes could be detected. The yields of the C{sub n-1} and C{sub n-2:1} hydrocarbons were comparable with those found in irradiated lipids of land animals and plants. However, in cod and the prawn species which contain high levels of polyunsaturated fatty acids (PUFA), the C{sub n-1} hydrocarbons were found in concentrations up to tenfold higher whereas the C{sub n-2:1} products were again comparable to those of land animals and plants. The identification of radiation-induced hydrocarbons in fish lipids was achieved by transfer of the hydrocarbons from the LC column to the gas chromatographic column in fractions differing in the degree of unsaturation. For the first time radiation induced hydrocarbons with more than four double bonds generated from polyunsaturated fatty acids (20:4{omega}6 and 20:5{omega}3) could be identified. (orig.) [Deutsch] Radiolytische Kohlenwasserstoffe in Heilbutt, Kabeljau und Riesengarnelen wurden mit on-line gekoppelter Fluessigchromatographie-Gaschromatographie (LC-GC) in Kombination mit Massenspektrometrie nachgewiesen. In bestrahltem Heilbutt, der als Vertreter der fettreichen Fischarten hauptsaechlich gesaettigte und einfach ungesaettigte Fettsaeuren enthaelt, konnten alle erwarteten radiolytschen Alkane, Alkene und Alkadiene detektiert werden. Die Ausbeuten an C{sub n-1} und C{sub n-2:1} Kohlenwasserstoffen waren vergleichbar mit denen in bestrahlten Landtier- und Pflanzenfetten. In bestrahltem Kabeljau dagegen sowie in den bestrahlten Riesengarnelen, die beide zur fettarmen Kategorie gehoeren und hohe Konzentrationen an polyungesaettigten Fettsaeuren (PUFA) aufweisen

  3. FAST

    DEFF Research Database (Denmark)

    Zuidmeer-Jongejan, Laurian; Fernandez-Rivas, Montserrat; Poulsen, Lars K.

    2012-01-01

    ABSTRACT: The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT), using subcutaneous injections with aqu......ABSTRACT: The FAST project (Food Allergy Specific Immunotherapy) aims at the development of safe and effective treatment of food allergies, targeting prevalent, persistent and severe allergy to fish and peach. Classical allergen-specific immunotherapy (SIT), using subcutaneous injections...... with aqueous food extracts may be effective but has proven to be accompanied by too many anaphylactic side-effects. FAST aims to develop a safe alternative by replacing food extracts with hypoallergenic recombinant major allergens as the active ingredients of SIT. Both severe fish and peach allergy are caused...... in depth serological and cellular immune analyses will be performed, allowing identification of novel biomarkers for monitoring treatment efficacy. FAST aims at improving the quality of life of food allergic patients by providing a safe and effective treatment that will significantly lower their threshold...

  4. Rapid qualitative urinary tract infection pathogen identification by SeptiFast real-time PCR.

    Directory of Open Access Journals (Sweden)

    Lutz E Lehmann

    Full Text Available BACKGROUND: Urinary tract infections (UTI are frequent in outpatients. Fast pathogen identification is mandatory for shortening the time of discomfort and preventing serious complications. Urine culture needs up to 48 hours until pathogen identification. Consequently, the initial antibiotic regimen is empirical. AIM: To evaluate the feasibility of qualitative urine pathogen identification by a commercially available real-time PCR blood pathogen test (SeptiFast® and to compare the results with dipslide and microbiological culture. DESIGN OF STUDY: Pilot study with prospectively collected urine samples. SETTING: University hospital. METHODS: 82 prospectively collected urine samples from 81 patients with suspected UTI were included. Dipslide urine culture was followed by microbiological pathogen identification in dipslide positive samples. In parallel, qualitative DNA based pathogen identification (SeptiFast® was performed in all samples. RESULTS: 61 samples were SeptiFast® positive, whereas 67 samples were dipslide culture positive. The inter-methodological concordance of positive and negative findings in the gram+, gram- and fungi sector was 371/410 (90%, 477/492 (97% and 238/246 (97%, respectively. Sensitivity and specificity of the SeptiFast® test for the detection of an infection was 0.82 and 0.60, respectively. SeptiFast® pathogen identifications were available at least 43 hours prior to culture results. CONCLUSION: The SeptiFast® platform identified bacterial DNA in urine specimens considerably faster compared to conventional culture. For UTI diagnosis sensitivity and specificity is limited by its present qualitative setup which does not allow pathogen quantification. Future quantitative assays may hold promise for PCR based UTI pathogen identification as a supplementation of conventional culture methods.

  5. Vibration suppression of robot arm feedforward control with on-line parameter identification; Online kansei dotei ni yoru robot arm no feedforward shindo yokusei seigyo

    Energy Technology Data Exchange (ETDEWEB)

    Iwasaki, M.; Kuze, Y.; Otsuka, K.; Matsui, N. [Nagoya Institute of Technology, Nagoya (Japan)

    1997-12-20

    Generally, robot arms with flexible joints are multi-mass resonant systems, thus causing mechanical vibration. Since the vibration deteriorates the arm position control accuracy, the vibration suppression is indispensable to achieve the high performance arm motion. The authors have already proposed a feedforward vibration suppression scheme using an optimal control command shaping. The scheme is suitable for practical industrial use because of its simple control algorithm, however, there still remains a problem inherent in feedforward techniques that parameter setting errors in controller have significant effects on the suppression control accuracy. This paper presents an adaptive feedforward control of the vibration suppression with on-line mechanical parameter identifier, based on the proposed command shaping. In this scheme, the on-line identification of arm inertia using a method of least squares is performed during acceleration in arm motion. The identified parameter is used during deceleration to suppress the residual vibration. Experimental results using a prototype show the effectiveness of the proposed control. 9 refs., 10 figs., 2 tabs.

  6. On-line analysis of penicillin blood levels in the live rat by combined microdialysis/fast-atom bombardment mass spectrometry.

    OpenAIRE

    Caprioli, R.M.; Lin, S. N.

    1990-01-01

    The combination of microdialysis and fast-atom bombardment mass spectrometry has been used to follow the pharmacokinetics of penicillin G directly in the blood-stream of a live rat. After the intramuscular injection of the antibiotic, the blood dialysate was allowed to flow into the mass spectrometer via the continuous-flow/fast-atom bombardment interface. Tandem mass spectrometry provided the means for isolating and recording the ion fragments produced from the drug as the dialysate was expo...

  7. Toxicological screening of human plasma by on-line SPE-HPLC-DAD: identification and quantification of basic drugs and metabolites.

    Science.gov (United States)

    Mut, Ludmila; Grobosch, Thomas; Binscheck-Domaß, Torsten; Frenzel, Wolfgang

    2015-06-01

    An automated multi-analyte screening method for the identification and quantification of 92 drugs and metabolites based on on-line solid-phase extraction-high-performance liquid chromatography-diode array detection technique was developed and successfully validated. In addition, a database with 870 entries including UV-spectra, relative/retention times and response factors of toxicologically relevant compounds was created. Plasma samples (0.2 mL) were treated with methanol, diluted with buffer and on-line extracted (Strata X, 20 ×2 mm, 25 µm) at pH 9. Analytical separation was carried out on a Gemini NX column (150 ×4.6 mm, 3 µm) using gradient elution with acetonitrile-water (90:10,v/v) and 0.05 m potassium dihydrogen phosphate buffer (pH 2.3). Linear calibration curves with correlation coefficients ≥0.9950 were obtained for 78 analytes. As an additional benefit, the newly developed method allows the quantification of 42 analytes (e.g. antidepressants, neuroleptics and anticonvulsants) in a concentration range suitable for therapeutic drug monitoring. Limits of quantitation ranged from 0.02 mg/L (chlordiazepoxide) to 3.4 mg/L (mexiletine). Inter- and intra-day precisions of quality control samples (low/high) were better than 15% (zolpidem) and accuracy (bias) ranged from -11% (opipramol, venlafaxine) to 11% (venlafaxine, trazodone). Tests for carry-over and sample stability under different storage conditions were also performed and stability was adequate. Four cases of poisoning analysis are presented.

  8. Fast determination of the relative elemental and organic carbon content of aerosol samples by on-line single-particle aerosol time-of-flight mass spectrometry.

    Science.gov (United States)

    Ferge, T; Karg, E; Schröppel, A; Coffee, K R; Tobias, H J; Frank, M; Gard, E E; Zimmermann, R

    2006-05-15

    Different particulate matter (PM) samples were investigated by on-line single-particle aerosol time-of-flight mass spectrometry (ATOFMS). The samples consist of soot particulates made by a diffusion flame soot generator (combustion aerosol standard, CAST), industrially produced soot material (printex), soot from a diesel passenger car as well as ambient particulates (urban dust (NIST) and road tunnel dust). Five different CAST soot particle samples were generated with different elemental carbon (EC) and organic carbon (OC) content. The samples were reaerosolized and on-line analyzed by ATOFMS, as well as precipitated on quartz filters for conventional EC/OC analysis. For each sample ca. 1000 ATOFMS single-particle mass spectra were recorded and averaged. A typical averaged soot ATOFMS mass spectrum shows characteristic carbon cluster peak progressions (Cn+) as well as hydrogen-poor carbon cluster peaks (CnH(1-3)+). These peaks are originated predominately from the elemental carbon (EC) content of the particles. Often additional peaks, which are not due to carbon clusters, are observed, which either are originated from organic compounds (OC-organic carbon), or from the non-carbonaceous inorganic content of the particles. By classification of the mass spectral peaks as elemental carbon (i.e., the carbon cluster progression peaks) or as peaks originated from organic compounds (i.e., molecular and fragment ions), the relative abundance of elemental (EC) and organic carbon (OC) can be determined. The dimensionless TC/EC values, i.e., the ratio of total carbon content (TC, TC = OC + EC) to elemental carbon (EC), were derived from the ATOFMS single-particle aerosol mass spectrometry data. The EC/TC values measured by ATOFMS were compared with the TC/EC values determined by the thermal standard techniques (thermooptical and thermocoulometric method). A good agreement between the EC/TC values obtained by on-line ATOFMS and the offline standard method was found.

  9. PILER-CR: Fast and accurate identification of CRISPR repeats

    Directory of Open Access Journals (Sweden)

    Edgar Robert C

    2007-01-01

    Full Text Available Abstract Background Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar length. The distinctive sequence signature of CRISPR repeats can be found using general-purpose repeat- or pattern-finding software tools. However, the output of such tools is not always ideal for studying these repeats, and significant effort is sometimes needed to build additional tools and perform manual analysis of the output. Results We present PILER-CR, a program specifically designed for the identification and analysis of CRISPR repeats. The program executes rapidly, completing a 5 Mb genome in around 5 seconds on a current desktop computer. We validate the algorithm by manual curation and by comparison with published surveys of these repeats, finding that PILER-CR has both high sensitivity and high specificity. We also present a catalogue of putative CRISPR repeats identified in a comprehensive analysis of 346 prokaryotic genomes. Conclusion PILER-CR is a useful tool for rapid identification and classification of CRISPR repeats. The software is donated to the public domain. Source code and a Linux binary are freely available at http://www.drive5.com/pilercr.

  10. 在线参数辨识的脉冲噪声有源控制%Active Control of Impulsive Noise Based on On-line Parameter Identification

    Institute of Scientific and Technical Information of China (English)

    杨琴; 周亚丽; 张奇志

    2013-01-01

    Active noise control is a kind of active control methods and has been widely used to attenuate the noise which yields Gaussian distribution. But for most of non-Gaussian impulsive noises, the traditional adaptive algorithms are not appropriate for controlling the impulsive noise. The main reason is that there is no finite second-order moment for the impulsive noise. In this paper, two kinds of on-line parameter identification algorithms based on the classical Filter-x LMS algorithm were presented which are appropriate for non-Gaussian impulsive noise. One is FxLMPest and FxLMADadapt algorithms based on on-line parameters identification to estimate characteristics exponent of impulsive noise with an SαS distribution, and the other is BDP algorithm based on SKM and AM algorithms presented by Sun et al, which uses a simple on-line recursive procedure to estimate amplitude thresholds. Both methods do not need prior information of characteristics exponent and amplitude thresholds of impulsive noise. And the simulation results also show that the two methods can effectively suppress the impulsive noise, and its robust performance is significantly better than Filter-x LMS algorithm.%  有源噪声控制是一种主动控制方法,目前已广泛应用于对高斯分布噪声进行衰减。但是传统的用于控制噪声的自适应算法不再适用大多数服从非高斯分布的脉冲噪声,主要原因是这种脉冲噪声没有有限的二阶统计量。在经典的Filter-x LMS算法的基础上提出两种适用于服从非高斯分布尖峰脉冲噪声情况下的在线参数辨识方法,一种是利用在线参数辨识方法对服从SαS稳定分布的脉冲噪声进行特征指数的估计,进而实现降噪目的的FxLMPest和FxLMADadapt算法;另一种是在Sun等人提出的SKM和AM算法基础上利用在线递归过程实现对幅度阈值估计的BDP算法。这两种算法均不需要获得脉冲噪声的特征指数和阈值的

  11. HPLC-DAD-ESI/MS Identification and Quantification of Phenolic Compounds in Ilex paraguariensis Beverages and On-Line Evaluation of Individual Antioxidant Activity

    Directory of Open Access Journals (Sweden)

    Delia B. Rodriguez-Amaya

    2013-03-01

    Full Text Available “Chimarrão” and “tererê” are maté (dried, toasted and milled Ilex paraguariensis leaves and stemlets beverages widely consumed in South America. This paper describes the application of HPLC-DAD-ESI/MS method for the identification and quantification of caffeoylquinic acids (CQA, flavonol glycosides and purine alkaloids in these beverages. The beverage samples were prepared from commercial lots of maté from Southern Brazil. The caffeoylquinic acids, 4,5-diCQA, 3-CQA, 5-CQA, and 4-CQA were the major compounds, having 238–289, 153–242, 183–263, and 123–188 μg/mL, respectively, for chimarrão and 206–265, 122–218, 164–209, 103–169 μg/mL, respectively, for tererê. Caffeine also had high amounts while glycosides of quercetin and kaempferol were found at much lower levels. The individual antioxidant activity was also determined by an on-line system that measured their ABTS•+ radical scavenging activity, showing that the antioxidant capacity was not proportional to the concentrations of the phenolic compounds. 3-CQA, quercetina-3-O-ramnosylglucoside, and quercetina-3-O-glucoside were the major contributors to the antioxidant capacity, although the quercetin glycosides had concentrations less than 10 times that of 3-CQA.

  12. HPLC-DAD-ESI/MS identification and quantification of phenolic compounds in Ilex paraguariensis beverages and on-line evaluation of individual antioxidant activity.

    Science.gov (United States)

    Peres, Renato G; Tonin, Fernando G; Tavares, Marina F M; Rodriguez-Amaya, Delia B

    2013-03-28

    "Chimarrão" and "tererê" are maté (dried, toasted and milled Ilex paraguariensis leaves and stemlets) beverages widely consumed in South America. This paper describes the application of HPLC-DAD-ESI/MS method for the identification and quantification of caffeoylquinic acids (CQA), flavonol glycosides and purine alkaloids in these beverages. The beverage samples were prepared from commercial lots of maté from Southern Brazil. The caffeoylquinic acids, 4,5-diCQA, 3-CQA, 5-CQA, and 4-CQA were the major compounds, having 238-289, 153-242, 183-263, and 123-188 μg/mL, respectively, for chimarrão and 206-265, 122-218, 164-209, 103-169 μg/mL, respectively, for tererê. Caffeine also had high amounts while glycosides of quercetin and kaempferol were found at much lower levels. The individual antioxidant activity was also determined by an on-line system that measured their ABTS•+ radical scavenging activity, showing that the antioxidant capacity was not proportional to the concentrations of the phenolic compounds. 3-CQA, quercetina-3-O-ramnosylglucoside, and quercetina-3-O-glucoside were the major contributors to the antioxidant capacity, although the quercetin glycosides had concentrations less than 10 times that of 3-CQA.

  13. Fast Source Camera Identification Using Content Adaptive Guided Image Filter.

    Science.gov (United States)

    Zeng, Hui; Kang, Xiangui

    2016-03-01

    Source camera identification (SCI) is an important topic in image forensics. One of the most effective fingerprints for linking an image to its source camera is the sensor pattern noise, which is estimated as the difference between the content and its denoised version. It is widely believed that the performance of the sensor-based SCI heavily relies on the denoising filter used. This study proposes a novel sensor-based SCI method using content adaptive guided image filter (CAGIF). Thanks to the low complexity nature of the CAGIF, the proposed method is much faster than the state-of-the-art methods, which is a big advantage considering the potential real-time application of SCI. Despite the advantage of speed, experimental results also show that the proposed method can achieve comparable or better performance than the state-of-the-art methods in terms of accuracy.

  14. Improving Peak Capacity in Fast On-Line Comprehensive Two-Dimensional Liquid Chromatography with Post First Dimension Flow-Splitting

    Science.gov (United States)

    Filgueira, Marcelo R.; Huang, Yuan; Witt, Klaus; Castells, Cecilia; Carr, Peter W.

    2011-01-01

    The use of flow splitters between the two dimensions in on-line comprehensive two dimensional liquid chromatography (LC×LC) has not received very much attention in comparison to their use in GC×GC where they are quite common. In principle, splitting the flow after the first dimension column and performing on-line LC×LC on this constant fraction of the first dimension effluent should allow the two dimensions to be optimized almost independently. When there is no flow splitting any change in the first dimension flow rate has an immediate impact on the second dimension. With a flow splitter one could for example double the flow rate into the first dimension column and do a 1:1 flow split without changing the sample loop size or the sampler’s collection time. Of course, the sensitivity would be diminished but this can be partially compensated by use of a larger injection; this will likely only amount to a small price to pay for this increased resolving power and system flexibility. Among other benefits, we found a 2-fold increase in the corrected 2D peak capacity and the number of observed peaks for a 15 min analysis time by using a post first dimension flow splitter. At a fixed analysis time this improvement results primarily from an increase in the gradient time resulting from the reduced system re-equilibration time and to a smaller extent it is due to the increased peak capacity achieved by full optimization of the first dimension. PMID:22017622

  15. Fast and reliable identification of microorganisms by means of Raman spectroscopy

    Science.gov (United States)

    Rösch, Petra; Harz, Michaela; Krause, Mario; Popp, Jürgen

    2007-07-01

    The identification of bacteria is necessary as fast as possible e.g. to provide an appropriate therapy for patients. Here the cultivation time should be kept to a minimum. Beside microbiological identification methods Raman spectroscopy is a valuable tool for bacteria identification. UV-resonance Raman spectroscopy enables selective monitoring of the cellular DNA/RNA content and allows for a genotaxonomic classification of the bacteria. Since UV excitation may lead to sample destruction the measurements are performed on rotated bacterial films. For a faster identification avoiding the cultivation step single bacteria analysis is necessary. Using micro-Raman spectroscopy a spatial resolution in the size range of the bacteria can be achieved. With this Raman excitation the chemical components of the whole cell are measured which leads to a phenotypic classification. For localization of bacteria inside complex matrices fluorescence labeling is achieved.

  16. Fast and robust identification of single bacteria in environmental matrices by Raman spectroscopy

    Science.gov (United States)

    Baritaux, Jean-Charles; Schultz, Emmanuelle; Simon, Anne-Catherine; Bourdat, Anne-Gaelle; Espagnon, Isabelle; Laurent, Patricia; Dinten, Jean-Marc

    2015-03-01

    We report on our recent results on robust identification of single bacterial cells embedded in various environments using Spontaneous Raman Scattering. Five species of bacteria were considered, two of which (B. Subtilis and E. Coli) were grown under various conditions, or embedded in two real-world matrices. We recorded the Raman spectra of single cells with a confocal instrument developed in our lab, and performed identification at the species level. Our system integrates a Lensfree imaging module that allows fast detection of bacteria over a large Field-Of-View. Identification rates comparable to those obtained on lab cultures were possible using a comprehensive database containing spectra from bacteria in all environments. In addition, B. Subtilis was correctly identified in 95.5% of the cases using a database composed exclusively of spectra obtained in standard conditions. This is very promising for pathogen threat detection where the construction of an exhaustive database may be challenging.

  17. Fast and reliable identification of axons, axon initial segments and dendrites with local field potential recording

    Directory of Open Access Journals (Sweden)

    Anders Victor ePetersen

    2015-10-01

    Full Text Available The axon initial segment (AIS is an essential neuronal compartment. It is usually where action potentials are initiated. Recent studies demonstrated that the AIS is a plastic structure that can be regulated by neuronal activity and by the activation of metabotropic receptors. Studying the AIS in live tissue can be difficult because its identification is not always reliable. Here we provide a new technique allowing a fast and reliable identification of the AIS in live brain slice preparations. By simultaneous recoding of extracellular local field potentials and whole-cell patch-clamp recording of neurons, we can detect sinks caused by inward currents flowing across the membrane. We determine the location of the AIS by comparing the timing of these events with the action potential. We demonstrate that this method allows the unequivocal identification of the AIS of different types of neurons from the brain.

  18. A fully automated and fast method using direct sample injection combined with fused-core column on-line SPE-HPLC for determination of ochratoxin A and citrinin in lager beers.

    Science.gov (United States)

    Lhotská, Ivona; Šatínský, Dalibor; Havlíková, Lucie; Solich, Petr

    2016-05-01

    A new fast and sensitive method based on on-line solid-phase extraction on a fused-core precolumn coupled to liquid chromatography with fluorescence detection has been developed for ochratoxin A (OTA) and citrinin (CIT) determination in lager beer samples. Direct injection of 100 μL filtered beer samples into an on-line SPE-HPLC system enabled fast and effective sample extraction including separation in less than 6 min. Preconcentration of OTA and CIT from beer samples was performed on an Ascentis Express RP C18 guard column (5 × 4.6 mm), particle size 2.7 μm, with a mobile phase of methanol/0.5% aqueous acetic acid pH 2.8 (30:70, v/v) at a flow rate of 2.0 mL min(-1). The flow switch from extraction column to analytical column in back-flush mode was set at 2.0 min and the separation was performed on the fused-core column Ascentis Express Phenyl-Hexyl (100 × 4.6 mm), particle size 2.7 μm, with a mobile phase acetonitrile/0.5% aqueous acetic acid pH 2.8 in a gradient elution at a flow rate of 1.0 mL min(-1) and temperature of 50 °C. Fluorescence excitation/emission detection wavelengths were set at 335/497 nm. The accuracy of the method, defined as the mean recoveries of OTA and CIT from light and dark beer samples, was in the range 98.3-102.1%. The method showed high sensitivity owing to on-line preconcentration; LOQ values were found to be 10 and 20 ng L(-1) for OTA and CIT, respectively. The found values of OTA and CIT in all tested light, dark and wheat beer samples were significantly below the maximum tolerable limits (3.0 μg kg(-1) for OTA and 2000 μg kg(-1) for CIT) set by the European Union.

  19. Wind turbine control systems: Dynamic model development using system identification and the fast structural dynamics code

    Energy Technology Data Exchange (ETDEWEB)

    Stuart, J.G.; Wright, A.D.; Butterfield, C.P.

    1996-10-01

    Mitigating the effects of damaging wind turbine loads and responses extends the lifetime of the turbine and, consequently, reduces the associated Cost of Energy (COE). Active control of aerodynamic devices is one option for achieving wind turbine load mitigation. Generally speaking, control system design and analysis requires a reasonable dynamic model of {open_quotes}plant,{close_quotes} (i.e., the system being controlled). This paper extends the wind turbine aileron control research, previously conducted at the National Wind Technology Center (NWTC), by presenting a more detailed development of the wind turbine dynamic model. In prior research, active aileron control designs were implemented in an existing wind turbine structural dynamics code, FAST (Fatigue, Aerodynamics, Structures, and Turbulence). In this paper, the FAST code is used, in conjunction with system identification, to generate a wind turbine dynamic model for use in active aileron control system design. The FAST code is described and an overview of the system identification technique is presented. An aileron control case study is used to demonstrate this modeling technique. The results of the case study are then used to propose ideas for generalizing this technique for creating dynamic models for other wind turbine control applications.

  20. Assessment of the quality of dna extracted by two techniques from Mycobacterium tuberculosis for fast molecular identification and genotyping

    Directory of Open Access Journals (Sweden)

    Marcelo Miyata

    2011-06-01

    Full Text Available We report a comparative study of two DNA extraction techniques, thermolysis and chemical lysis (CTAB, for molecular identification and genotyping of M. tuberculosis. Forty DNA samples were subjected to PCR and the results demonstrated that with thermolysis it is possible to obtain useful data that enables fast identification and genotyping.

  1. Identification of glyceollin metabolites derived from conjugation with glutathione and glucuronic acid in rats by on-line liquid chromatography-electrospray ionization tandem mass spectrometry

    Science.gov (United States)

    Glyceollin-related metabolites produced in rats following oral glyceollin administration were screened and identified by precursor and product ion scanning using liquid chromatography, coupled on-line with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS), to identify all glyceollin me...

  2. A fast iterative recursive least squares algorithm for Wiener model identification of highly nonlinear systems.

    Science.gov (United States)

    Kazemi, Mahdi; Arefi, Mohammad Mehdi

    2016-12-15

    In this paper, an online identification algorithm is presented for nonlinear systems in the presence of output colored noise. The proposed method is based on extended recursive least squares (ERLS) algorithm, where the identified system is in polynomial Wiener form. To this end, an unknown intermediate signal is estimated by using an inner iterative algorithm. The iterative recursive algorithm adaptively modifies the vector of parameters of the presented Wiener model when the system parameters vary. In addition, to increase the robustness of the proposed method against variations, a robust RLS algorithm is applied to the model. Simulation results are provided to show the effectiveness of the proposed approach. Results confirm that the proposed method has fast convergence rate with robust characteristics, which increases the efficiency of the proposed model and identification approach. For instance, the FIT criterion will be achieved 92% in CSTR process where about 400 data is used.

  3. A Low Delay and Fast Converging Improved Proportionate Algorithm for Sparse System Identification

    Directory of Open Access Journals (Sweden)

    Andy W. H. Khong

    2007-04-01

    Full Text Available A sparse system identification algorithm for network echo cancellation is presented. This new approach exploits both the fast convergence of the improved proportionate normalized least mean square (IPNLMS algorithm and the efficient implementation of the multidelay adaptive filtering (MDF algorithm inheriting the beneficial properties of both. The proposed IPMDF algorithm is evaluated using impulse responses with various degrees of sparseness. Simulation results are also presented for both speech and white Gaussian noise input sequences. It has been shown that the IPMDF algorithm outperforms the MDF and IPNLMS algorithms for both sparse and dispersive echo path impulse responses. Computational complexity of the proposed algorithm is also discussed.

  4. A Low Delay and Fast Converging Improved Proportionate Algorithm for Sparse System Identification

    Directory of Open Access Journals (Sweden)

    Benesty Jacob

    2007-01-01

    Full Text Available A sparse system identification algorithm for network echo cancellation is presented. This new approach exploits both the fast convergence of the improved proportionate normalized least mean square (IPNLMS algorithm and the efficient implementation of the multidelay adaptive filtering (MDF algorithm inheriting the beneficial properties of both. The proposed IPMDF algorithm is evaluated using impulse responses with various degrees of sparseness. Simulation results are also presented for both speech and white Gaussian noise input sequences. It has been shown that the IPMDF algorithm outperforms the MDF and IPNLMS algorithms for both sparse and dispersive echo path impulse responses. Computational complexity of the proposed algorithm is also discussed.

  5. Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.

    Science.gov (United States)

    Malherbe, Christiaan J; de Beer, Dalene; Joubert, Elizabeth

    2012-01-01

    Biochemical detection (BCD) methods are commonly used to screen plant extracts for specific biological activities in batch assays. Traditionally, bioactives in the most active extracts were identified through time-consuming bio-assay guided fractionation until single active compounds could be isolated. Not only are isolation procedures often tedious, but they could also lead to artifact formation. On-line coupling of BCD assays to high performance liquid chromatography (HPLC) is gaining ground as a high resolution screening technique to overcome problems associated with pre-isolation by measuring the effects of compounds post-column directly after separation. To date, several on-line HPLC-BCD assays, applied to whole plant extracts and mixtures, have been published. In this review the focus will fall on enzyme-based, receptor-based and antioxidant assays.

  6. Development of On-Line High Performance Liquid Chromatography (HPLC)-Biochemical Detection Methods as Tools in the Identification of Bioactives

    Science.gov (United States)

    Malherbe, Christiaan J.; de Beer, Dalene; Joubert, Elizabeth

    2012-01-01

    Biochemical detection (BCD) methods are commonly used to screen plant extracts for specific biological activities in batch assays. Traditionally, bioactives in the most active extracts were identified through time-consuming bio-assay guided fractionation until single active compounds could be isolated. Not only are isolation procedures often tedious, but they could also lead to artifact formation. On-line coupling of BCD assays to high performance liquid chromatography (HPLC) is gaining ground as a high resolution screening technique to overcome problems associated with pre-isolation by measuring the effects of compounds post-column directly after separation. To date, several on-line HPLC-BCD assays, applied to whole plant extracts and mixtures, have been published. In this review the focus will fall on enzyme-based, receptor-based and antioxidant assays. PMID:22489144

  7. On-line identification of lysergic acid diethylamide (LSD) in tablets using a combination of a sweeping technique and micellar electrokinetic chromatography/77 K fluorescence spectroscopy.

    Science.gov (United States)

    Fang, Ching; Liu, Ju-Tsung; Lin, Cheng-Huang

    2003-03-01

    This work describes a novel method for the accurate determination of lysergic acid diethylamide (LSD) in tablets. A technique involving sweeping-micellar electrokinetic chromatography (MEKC) was used for the initial on-line concentration and separation, after which a cryogenic molecular fluorescence experiment was performed at 77 K. Using this approach, not only the separation of LSD from the tablet extract was achieved, but on-line spectra were readily distinguishable and could be unambiguously assigned. The results are in agreement with analyses by gas chromatography-mass spectrometry (GC-MS). Thus, this method, which was found to be accurate, sensitive and rapid, has the potential for use as a reliable complementary method to GC-MS in such analyses.

  8. Fast Bayesian approach for modal identification using free vibration data, Part I - Most probable value

    Science.gov (United States)

    Zhang, Feng-Liang; Ni, Yan-Chun; Au, Siu-Kui; Lam, Heung-Fai

    2016-03-01

    The identification of modal properties from field testing of civil engineering structures is becoming economically viable, thanks to the advent of modern sensor and data acquisition technology. Its demand is driven by innovative structural designs and increased performance requirements of dynamic-prone structures that call for a close cross-checking or monitoring of their dynamic properties and responses. Existing instrumentation capabilities and modal identification techniques allow structures to be tested under free vibration, forced vibration (known input) or ambient vibration (unknown broadband loading). These tests can be considered complementary rather than competing as they are based on different modeling assumptions in the identification model and have different implications on costs and benefits. Uncertainty arises naturally in the dynamic testing of structures due to measurement noise, sensor alignment error, modeling error, etc. This is especially relevant in field vibration tests because the test condition in the field environment can hardly be controlled. In this work, a Bayesian statistical approach is developed for modal identification using the free vibration response of structures. A frequency domain formulation is proposed that makes statistical inference based on the Fast Fourier Transform (FFT) of the data in a selected frequency band. This significantly simplifies the identification model because only the modes dominating the frequency band need to be included. It also legitimately ignores the information in the excluded frequency bands that are either irrelevant or difficult to model, thereby significantly reducing modeling error risk. The posterior probability density function (PDF) of the modal parameters is derived rigorously from modeling assumptions and Bayesian probability logic. Computational difficulties associated with calculating the posterior statistics, including the most probable value (MPV) and the posterior covariance matrix

  9. A framework for fast and secure packaging identification on mobile phones

    Science.gov (United States)

    Diephuis, Maurits; Voloshynovskiy, Svyatoslav; Holotyak, Taras; Stendardo, Nabil; Keel, Bruno

    2014-02-01

    In this paper, we address the problem of fast and secure packaging identification on mobile phones. It is a well known fact that consumer goods are counterfeited on a massive scale in certain regions of the world, illustrating how existing counter measures fall short or don't exist at all, as can be seen in the local absence of laws pertaining to brand protection. This paper introduces a technological tool that allows the consumer to quickly identify a product or package with a mobile device using a physical non-cloneable features in the form of a surface micro- structure image. This natural occurring identifier allows a producer or brand owner to track and trace all its products and gives the consumer a powerful tool to confirm the authenticity of an offered product.

  10. Fast Identification of Recycling Properties of Wall-Released Hydrogenic Neutrals in Divertor Plasma

    Institute of Scientific and Technical Information of China (English)

    LI Chengyue; DENG Baiquan; YAN Jiancheng; G. A. EMMERT

    2007-01-01

    A new bipartition neutral transport model was developed for quick identification of the recycling properties of the wall-released hydrogenic neutral particles in the vicinity of the divertor target plate. Based on this model, the numerical calculation results are fairly consistent with the results obtained with the 'multi-generation method'. This model can not only be utilized to provide a source term from neutral transport calculations for the B2 edge plasma transport code, which has been used to simulate edge plasma transport of an HL-2A divertor configuration, but can also be specifically applied for fast classification of the divertor plasma as high recycling or low recycling. Our results also show that the transmissivity is lower in the high-recycling regime.

  11. Toxicological screening of human plasma by on-line SPE-HPLC-DAD: identification and quantification of acidic and neutral drugs.

    Science.gov (United States)

    Mut, Ludmila; Grobosch, Thomas; Binscheck-Domaß, Torsten; Frenzel, Wolfgang

    2016-03-01

    A multi-analyte screening method for the quantification of 50 acidic/neutral drugs in human plasma based on on-line solid-phase extraction (SPE)-HPLC with photodiode array detection (DAD) was developed, validated and applied for clinical investigation. Acetone and methanol for protein precipitation, three different SPE materials (two electro-neutral, one strong anion-exchange, one weak cation-exchange) for on-line extraction, five HPLC-columns [one C18 (GeminiNX), two phenyl-hexyl (Gemini C6 -Phenyl, Kinetex Phenyl-Hexyl) and two pentafluorophenyl (LunaPFP(2), KinetexPFP)] for analytical separation were tested. For sample pre-treatment, acetone in the ratio 1:2 (plasma:acetone) showed a better baseline and fewer matrix peaks in the chromatogram than methanol. Only the strong anion-exchanger SPE cartridge (StrataX-A, pH 6) allowed the extraction of salicylic acid. Analytical separation was carried out on a Gemini C6 -Phenyl column (150 × 4.6 mm, 3 µm) using gradient elution with acetonitrile-water 90:10 (v/v) and phosphate buffer (pH 2.3). Linear calibration curves with correlation coefficients r ≥ 0.9950/0.9910 were obtained for 46/four analytes. Additionally, this method allows the quantification of 23 analytes for therapeutic drug monitoring. Limits of quantitation ranged from 0.1 (amobarbital) to 23 mg/L (salicylic acid). Inter-/intra-day precisions of quality control samples (low/high) were better than 13% and accuracy (bias) ranged from -14 to 10%. A computer-assisted database was created for automated detection of 223 analytes of toxicological interests. Four cases of multi-drug intoxications are presented.

  12. Fast identification of microplastics in complex environmental samples by a thermal degradation method.

    Science.gov (United States)

    Dümichen, Erik; Eisentraut, Paul; Bannick, Claus Gerhard; Barthel, Anne-Kathrin; Senz, Rainer; Braun, Ulrike

    2017-05-01

    In order to determine the relevance of microplastic particles in various environmental media, comprehensive investigations are needed. However, no analytical method exists for fast identification and quantification. At present, optical spectroscopy methods like IR and RAMAN imaging are used. Due to their time consuming procedures and uncertain extrapolation, reliable monitoring is difficult. For analyzing polymers Py-GC-MS is a standard method. However, due to a limited sample amount of about 0.5 mg it is not suited for analysis of complex sample mixtures like environmental samples. Therefore, we developed a new thermoanalytical method as a first step for identifying microplastics in environmental samples. A sample amount of about 20 mg, which assures the homogeneity of the sample, is subjected to complete thermal decomposition. The specific degradation products of the respective polymer are adsorbed on a solid-phase adsorber and subsequently analyzed by thermal desorption gas chromatography mass spectrometry. For certain identification, the specific degradation products for the respective polymer were selected first. Afterwards real environmental samples from the aquatic (three different rivers) and the terrestrial (bio gas plant) systems were screened for microplastics. Mainly polypropylene (PP), polyethylene (PE) and polystyrene (PS) were identified for the samples from the bio gas plant and PE and PS from the rivers. However, this was only the first step and quantification measurements will follow.

  13. Fast and simple screening for the simultaneous analysis of seven metabolites derived from five volatile organic compounds in human urine using on-line solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Chiang, Wen-Chieh; Chen, Chao-Yu; Lee, Ting-Chen; Lee, Hui-Ling; Lin, Yu-Wen

    2015-01-01

    quantification (LOQ) were determined to within 0.010 to 0.769 ng mL(-1) and 0.033 to 2.564 ng mL(-1) in this study. A stability study test included 3 freeze/thaw cycles during short-term storage at room temperature for 36 h and long-term storage at -20 °C for 1 month, and the CV (coefficient of variation) showed less than 8.4, 7.4 and 9.7%, respectively. To the best of our knowledge, this is the first study to provide simple, small injection volumes (40 µL) and a rapid LC-MS/MS method combined with an on-line SPE step for the simultaneous detection, identification, and quantification of seven metabolites derived from five VOCs in human urine for evaluation of the future risk of human exposure to volatile organic compounds.

  14. Fast Nondestructive Identification of Endothelium Corneum Gigeriae Galli Using Visible/Near-Infrared Spectroscopy

    Institute of Scientific and Technical Information of China (English)

    张小燕; 孟耀勇; 张浩; 欧文娟; 刘颂豪

    2011-01-01

    Vis/NIR, spcctroscopy, in combination with partial least square (PLS) analysis and a back-propagation neural network, is investigated to identify cndothcliutn corncum gigeriae galli (EC'GG). The spectra] features of ECGGs and their counterfeits are reasonably differentiated in vis/NfR region, whicli provides enough qualitative information to establish the relationship between the spectra and samples for identification. After pretrcatment of the spectral data, cross validation is implemented for extracting the frest number of principal components. Then the calibration and validation set arc performed well. The PLS and back propagation neural network (BPNN) model gives the BPNN to be 0.9941 and the root mean square residual (RMSR) to be 0.0775 for the calibration set, and the multiple correlation coefficient (MCC) to 0.9874 and the RMSE to 0.1134 for the validation set. Thus the PLS and BPNN model is reliable and practicable. Through testing, a recognition accuracy of 100% is achieved. The present study could offer a new approach for fast and nondestructive discrimination ofECGG and its counterfeit.%Vis/NIR spectroscopy,in combination with partial least square(PLS)analysis and a back-propagation neural network,is investigated to identify endothclium corneum gigeriae galli(ECGG).The spectral features of ECGGs and their counterfeits are reasonably differentiated in vis/NIR region,which provides enough qualitative information to establish the relationship between the spectra and samples for identification.After pretreatment of the spectral data,cross validation is implemented for extracting the best number of principal components.Then the calibration and validation set are performed well The PLS and back propagation neural network(BPNN)model gives the BPNN to be 0.9941 and the root mean square residual(RMSR)to be 0.0775 for the calibration set,and the multiple correlation coeffcient(MCC)to 0.9874 and the RMSE to 0.1134 for the validation set.Thus the PLS and BPNN model

  15. Hollow fiber based quantum cascade laser spectrometer for fast and sensitive drug identification

    Science.gov (United States)

    Herbst, J.; Scherer, B.; Ruf, A.; Erb, J.; Lambrecht, A.

    2012-01-01

    Sensitive and fast identification of drugs or drug precursors is important and necessary in scenarios like baggage or container check by customs or police. Fraunhofer IPM is developing a laser spectrometer using external cavity quantum cascade lasers (EC-QCL) to obtain mid-infrared (IR) absorption spectra in the wavelength range of the specific vibrational bands of amphetamines and their precursors. The commercial EC-QCL covers a tuning range of about 225 cm-1 within 1.4 s. The system could be used for different sample types like bulk samples or liquid solutions. A sampling unit evaporates the sample. Because of small sample amounts a 3 m long hollow fiber with an inner volume smaller than 1ml is used as gas cell and wave guide for the laser beam. This setup is suitable as a detector of a gas chromatograph instead of a standard detector (TCD or FID). The advantage is the selective identification of drugs by their IR spectra in addition to the retention time in the gas chromatographic column. In comparison to Fourier Transform IR systems the EC-QCL setup shows a good mechanical robustness and has the advantage of a point light source. Because of the good fiber incoupling performance of the EC-QCL it is possible to use hollow fibers. So, a good absorption signal is achieved because of the long optical path in the small cell volume without significant dilution. In first laboratory experiments a detection limit in the microgram range for pseudo ephedrine is achieved.

  16. Fast island phase identification for tearing mode feedback control on J-TEXT tokamak

    Science.gov (United States)

    Rao, B.; Li, D.; Hu, F. R.; Ding, Y. H.; Hu, Q. M.; Jin, H.

    2016-11-01

    A new method to control the tearing mode (TM) in tokamaks has been proposed [Q. Hu and Q. Yu, Nucl. Fusion 56, 034001 (5pp.) (2016)], according to which, the external resonant magnetic perturbation needs to be applied in certain magnetic island phase regions. Therefore, it is very important to identify the helical phase of magnetic islands in real time. The TM in tokamak plasmas is normally rotating and carries magnetic oscillations, which are known as Mirnov oscillations and can be detected by Mirnov probes. When the O-point or X-point of the magnetic island passes through the probe, the signal will experience a zero-crossing. A poloidal Mirnov probe array and a corresponding island phase identification method are presented. A field-programmable gate array is used to provide the magnetic island helical phase in real time by using multichannel zero crossing detection. This system has been developed on the J-TEXT tokamak and works well. This paper introduces the establishment of the fast magnetic island phase identifying system.

  17. Fast identification of wine related lactic acid bacteria by multiplex PCR.

    Science.gov (United States)

    Petri, A; Pfannebecker, J; Fröhlich, J; König, H

    2013-02-01

    The microflora of must and wine consists of yeasts, acetic acid bacteria and lactic acid bacteria (LAB). The latter group plays an important role for wine quality. The malolactic fermentation carried out by LAB leads to deacidification and stabilisation of wines. Nevertheless, LAB are often associated with wine spoilage. They are mainly responsible for the formation of biogenic amines. Furthermore, some strains produce exopolysaccharide slimes, acetic acid, diacetyl and other off-flavours. In this context a better monitoring of the vinification process is crucial to improve wine quality. Moreover, a lot of biodiversity studies would also profit from a fast and reliable identification method. In this study, we propose a species-specific multiplex PCR system for a rapid and simultaneous detection of 13 LAB species, frequently occurring in must or wine: Lactobacillus brevis, Lb. buchneri, Lb. curvatus, Lb. hilgardii, Lb. plantarum, Leuconostoc mesenteroides, Oenococcus oeni, Pediococcus acidilactici, P. damnosus, P. inopinatus, P. parvulus, P. pentosaceus and Weissella paramesenteroides.

  18. Identification of fast-evolving genes in the scleractinian coral Acropora using comparative EST analysis.

    Directory of Open Access Journals (Sweden)

    Akira Iguchi

    Full Text Available To identify fast-evolving genes in reef-building corals, we performed direct comparative sequence analysis with expressed sequence tag (EST datasets from two acroporid species: Acropora palmata from the Caribbean Sea and A. millepora from the Great Barrier Reef in Australia. Comparison of 589 independent sequences from 1,421 A. palmata contigs, with 10,247 A. millepora contigs resulted in the identification of 196 putative homologues. Most of the homologous pairs demonstrated high amino acid similarities (over 90%. Comparisons of putative homologues showing low amino acid similarities (under 90% among the Acropora species to the near complete datasets from two other cnidarians (Hydra magnipapillata and Nematostella vectensis implied that some were non-orthologous. Within 86 homologous pairs, 39 exhibited dN/dS ratios significantly less than 1, suggesting that these genes are under purifying selection associated with functional constraints. Eight independent genes showed dN/dS ratios exceeding 1, while three deviated significantly from 1, suggesting that these genes may play important roles in the adaptive evolution of Acropora. Our results also indicated that CEL-III lectin was under positive selection, consistent with a possible role in immunity or symbiont recognition. Further studies are needed to clarify the possible functions of the genes under positive selection to provide insight into the evolutionary process of corals.

  19. Optical and fast nondestructive identification of the ages of leaded ancient pottery

    Institute of Scientific and Technical Information of China (English)

    Wu Fang-Yuan; Yang Xiang-Bo

    2012-01-01

    In this paper,based on the one-dimensional(1D)optical superlattice model,we calculate the average reflectivities(ARs)of leaded ancient pottery(AP)made within the last 2000 years,and find that for incident light with a suitable wavelength,the AR of the leaded AP increases monotonously with the increase in the layer number of the silvery glaze(SG)media.Based on this property,we propose an optical nondestructive method for identifying the age of leaded AP by detecting the AR.By using the exhaust algorithm and the discriminant function of variance,we obtain the optimal wavelength range of the incident light to identify the ages of the leaded AP.It is found that in the visible light band,if we choose green light with a wavelength range of 540-540.1 nm as the incident light,leaded AP made within the last 2000 years can be identified swiftly and precisely by detecting the ARs.This will be useful for designing optical instruments for the fast nondestructive identification of the ages of leaded AP.

  20. Acetobacter aceti fast identification by Real Time PCR in spoiled wine samples

    Directory of Open Access Journals (Sweden)

    Attila Kántor

    2014-11-01

    Full Text Available Wine is a beverage that made from grape berries. However, without beneficial bacteria, we would not produce good wine. But very often wines contain acetic acid bacteria, which are undesirable in winemaking process. Acetic acid bacteria as known as a vinegar bacteria are Gram-negative, aerobic, rod-shaped and ubiquitous bacteria. This study was focused on species of acetic acid bacteria, specifically Acetobacter aceti that make spoilage in wine.The aim of our study was the identification of Acetobacter aceti in spoiled red wine samples, with plate dilution method on agar plates and using sensitive Real-time PCR (qPCR method. We cultivated Acetobacter aceti on GYC agar at 30°C, 48h. The one of main objective in the present work was the test fast, sensitive and reliable technique such as quantitative Real-time PCR and detecting the presence of Acetobacter aceti in wine samples with positive Acetobacteraceti control on amplification plot and melting curve. The next objective before  qPCR analysis was DNA extraction from wine samples incubated for one week at 28°C aerobically. We used five different red wine samples for this experiment: Alibernet 2013, Blaufränkisch 2013, Cabernet Sauvignon 2013, Dunaj 2012 and Saint-Laurent 2012. Next we extracted DNA from wine samples and from pure Acetobacter aceti CCM 3620T strain purchased from Czech collection of microorganisms in Brno. Susceptibility ofAcetobacter aceti was varied in different isolates from 102 to 107 CFU.mL-1. The number of Acetobacter cells on GYC medium ranged from 4.05 to 4.83log CFU.mL-1 in differentwine samples.The higher number of Acetobacter cells (4.83 log CFU.mL-1 was found in Cabernet Sauvignon 2013 wine.

  1. Identification of Brucella by MALDI-TOF Mass Spectrometry. Fast and Reliable Identification from Agar Plates and Blood Cultures

    Science.gov (United States)

    Ferreira, Laura; Vega Castaño, Silvia; Sánchez-Juanes, Fernando; González-Cabrero, Sandra; Menegotto, Fabiola; Orduña-Domingo, Antonio

    2010-01-01

    Background MALDI-TOF mass spectrometry (MS) is a reliable method for bacteria identification. Some databases used for this purpose lack reference profiles for Brucella species, which is still an important pathogen in wide areas around the world. We report the creation of profiles for MALDI-TOF Biotyper 2.0 database (Bruker Daltonics, Germany) and their usefulness for identifying brucellae from culture plates and blood cultures. Methodology/Principal Findings We created MALDI Biotyper 2.0 profiles for type strains belonging to B. melitensis biotypes 1, 2 and 3; B. abortus biotypes 1, 2, 5 and 9; B. suis, B. canis, B ceti and B. pinnipedialis. Then, 131 clinical isolates grown on plate cultures were used in triplicate to check identification. Identification at genus level was always correct, although in most cases the three replicates reported different identification at species level. Simulated blood cultures were performed with type strains belonging to the main human pathogenic species (B. melitensis, B. abortus, B. suis and B. canis), and studied by MALDI-TOF MS in triplicate. Identification at genus level was always correct. Conclusions/Significance MALDI-TOF MS is reliable for Brucella identification to the genus level from culture plates and directly from blood culture bottles. PMID:21151913

  2. Identification of Brucella by MALDI-TOF mass spectrometry. Fast and reliable identification from agar plates and blood cultures.

    Directory of Open Access Journals (Sweden)

    Laura Ferreira

    Full Text Available BACKGROUND: MALDI-TOF mass spectrometry (MS is a reliable method for bacteria identification. Some databases used for this purpose lack reference profiles for Brucella species, which is still an important pathogen in wide areas around the world. We report the creation of profiles for MALDI-TOF Biotyper 2.0 database (Bruker Daltonics, Germany and their usefulness for identifying brucellae from culture plates and blood cultures. METHODOLOGY/PRINCIPAL FINDINGS: We created MALDI Biotyper 2.0 profiles for type strains belonging to B. melitensis biotypes 1, 2 and 3; B. abortus biotypes 1, 2, 5 and 9; B. suis, B. canis, B ceti and B. pinnipedialis. Then, 131 clinical isolates grown on plate cultures were used in triplicate to check identification. Identification at genus level was always correct, although in most cases the three replicates reported different identification at species level. Simulated blood cultures were performed with type strains belonging to the main human pathogenic species (B. melitensis, B. abortus, B. suis and B. canis, and studied by MALDI-TOF MS in triplicate. Identification at genus level was always correct. CONCLUSIONS/SIGNIFICANCE: MALDI-TOF MS is reliable for Brucella identification to the genus level from culture plates and directly from blood culture bottles.

  3. On-Line Item Attribute Identification in Cognitive Diagnostic Computerized Adaptive Testing%计算机化自适应诊断测验中原始题的属性标定

    Institute of Scientific and Technical Information of China (English)

    汪文义; 丁树良; 游晓锋

    2011-01-01

    . Secondly, test items are developed by specialists according to the attribute hierarchy and finally, the hierarchy of attributes and item attributes are necessary to be validated. In real situations, whether the items have or have not been identified attributes before its construction, it will cost a lot of money, require more efforts to identify attributes through specialists according the above described procedure and yet can't completely assume the correctness due to the subjectivity. As a result, invalid inferences about the student performance will be made if the attributes of some items are specified incorrectly. Chang (2010) pointed out that the on-line calibration for regular computerized adaptive testing may be one of the mosteffective processes. Although the great significance of Q-matrix in CDA has been widely recognized, few, if any, on-line item attribute identification has been found in the literature. So this study discussed how to implement the on-line item attribute identification in cognitive diagnostic computerized adaptive testing (CD-CAT).The study introduced three methods of on-line item attribute identification, Maximum Likelihood Estimation (MLE), Marginal Maximum Likelihood Estimation (MMLE) and a novel method named as Inter & Diff based on intersection and difference. The new method is Cognitive Diagnostic Model-free (CDM-free). In other words, when model-data fit is not so good, the Inter-Diff method could be employed to identify attributes in the raw items on-line. Intersection and difference are set operations in Set Theory.The simulation results showed that MMLE worked better than MLE and Inter & Diff, but MMLE was slightly sensitive to the fixed item parameters. Adaptively seeding raw items worked better than randomly seeding raw items when the correct classification rate of the entire pattern was relatively high. Especially when the attribute hierarchies are linear type, convergent type and syllogistic reasoning hierarchy, the result of Inter

  4. An On-line Identification of Equipment Risk for 3/2 Circuit Breaker Connections%针对电网3/2接线方式的设备风险在线辨识方法

    Institute of Scientific and Technical Information of China (English)

    闪鑫; 戴则梅; 曹路; 汪德星

    2012-01-01

    3/2接线方式由于具有供电可靠性高、运行调度灵活、倒闸操作方便等优点,在500kV厂站和部分220kV枢纽变电站得到了广泛应用。但是,该接线方式在一次设备或开关处于检修方式下时,某些故障模式可能会造成多个设备的停电。基于网络拓扑分析和保护动作逻辑的设备风险在线辨识技术,能够针对3/2接线方式下的一次设备或开关检修,自动识别出具有N-2以上停电设备的潜在故障模式,提醒调度运行人员;同时,结合静态安全分析、动态安全分析以及检修计划,实现大电网的设备风险在线防控。%Owing to lots of advantages such as high reliability for power supply,flexible operating and dispatching mechanism and convenient transfer switching,etc,the 3/2 connection mode has been widely put into operation in 500 kV power stations and some 200 kV load-center substations.However,many equipments may be subjected to power cut caused by some fault modes as long as the connection mode is linked with primary equipment or the breaker under prophylactic overhaul.Using on-line identification technology of equipment risk based on network topology analysis and operation logic for protection,it is able to automatically identify the latent fault mode concerning N-2 or more power-failure equipments for primary equipment or breaker overhaul under 3/2 connection mode,and reminds relevant dispatching working staff.In the meantime,through the combination of static and dynamic security analysis and maintenance schedule,it will achieve on-line prevention and control mechanism for equipment risk in large power grid.

  5. Effects of simulation-based practice on focused assessment with sonography for trauma (FAST) window identification, acquisition, and diagnosis.

    Science.gov (United States)

    Chung, Gregory K W K; Gyllenhammer, Ruth G; Baker, Eva L; Savitsky, Eric

    2013-10-01

    We compared the effects of simulator-based virtual ultrasound scanning practice with classroom-based ultrasound scanning practice on participants' knowledge of focused assessment with sonography for trauma (FAST) window quadrants and interpretation, and on participants' performance on live patient FAST examinations. Novices with little or no ultrasound training experience received simulation-based practice (n = 24) or classroom-based practice (n = 24). Participants who received simulation-based practice scored significantly higher on interpreting static images of FAST windows. On live patient examinations where participants scanned the right upper quadrant (RUQ), left upper quadrant (LUQ), and suprapubic quadrant of a normal patient and an ascites-positive patient, the classroom-based practice condition had a shorter scan time for the LUQ and a higher number of participants attaining high-quality window on the RUQ (normal patient only) and suprapubic quadrant (positive patient only) and correct window interpretation on the LUQ (normal patient only). Overall, classroom-based practice appeared to promote physical acquisition skills and simulator-based practice appeared to promote window interpretation skills. Accurate window interpretation is critical to identification of blunt abdominal trauma injuries. The simulator used (SonoSimulator) appears promising as a training tool to increase probe time and to increase exposure to FAST windows reflecting various anatomy and disease states.

  6. High-throughput analysis by SP-LDI-MS for fast identification of adulterations in commercial balsamic vinegars

    Energy Technology Data Exchange (ETDEWEB)

    Guerreiro, Tatiane Melina; Oliveira, Diogo Noin de; Ferreira, Mônica Siqueira; Catharino, Rodrigo Ramos, E-mail: rrc@fcm.unicamp.br

    2014-08-01

    Highlights: • Rapid identification of adulteration in balsamic vinegars. • Minimal sample preparation. • No matrix required for assisting laser desorption/ionization. • Fast sample discrimination by multivariate data analysis. - Abstract: Balsamic vinegar (BV) is a typical and valuable Italian product, worldwide appreciated thanks to its characteristic flavors and potential health benefits. Several studies have been conducted to assess physicochemical and microbial compositions of BV, as well as its beneficial properties. Due to highly-disseminated claims of antioxidant, antihypertensive and antiglycemic properties, BV is a known target for frauds and adulterations. For that matter, product authentication, certifying its origin (region or country) and thus the processing conditions, is becoming a growing concern. Striving for fraud reduction as well as quality and safety assurance, reliable analytical strategies to rapidly evaluate BV quality are very interesting, also from an economical point of view. This work employs silica plate laser desorption/ionization mass spectrometry (SP-LDI-MS) for fast chemical profiling of commercial BV samples with protected geographical indication (PGI) and identification of its adulterated samples with low-priced vinegars, namely apple, alcohol and red/white wines.

  7. Development of a fast DNA extraction method for sea food and marine species identification.

    Science.gov (United States)

    Tagliavia, Marcello; Nicosia, Aldo; Salamone, Monica; Biondo, Girolama; Bennici, Carmelo Daniele; Mazzola, Salvatore; Cuttitta, Angela

    2016-07-15

    The authentication of food components is one of the key issues in food safety. Similarly taxonomy, population and conservation genetics as well as food web structure analysis, also rely on genetic analyses including the DNA barcoding technology. In this scenario we developed a fast DNA extraction method without any purification step from fresh and processed seafood, suitable for any PCR analysis. The protocol allows the fast DNA amplification from any sample, including fresh, stored and processed seafood and from any waste of industrial fish processing, independently of the sample storage method. Therefore, this procedure is particularly suitable for the fast processing of samples and to carry out investigations for the authentication of seafood by means of DNA analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Formación on line On line learning

    Directory of Open Access Journals (Sweden)

    O. Grau-Perejoan

    2008-09-01

    Full Text Available La formación on line es una modalidad de enseñanza a distancia basada en las nuevas tecnologías. En este artículo se pretende hacer una introducción a base de describir a grandes rasgos sus características principales: asincronía, no presencialidad, comunicación escrita, función del profesor on line, así como los retos, los riesgos, las ventajas y los inconvenientes que plantea. Se exponen las diferencias entre la formación on line y la formación presencial, de manera que los docentes puedan adaptar de la mejor manera posible sus propuestas formativas a la modalidad on line. Se introduce el importantísimo papel de la planificación y de la fase de diseño y, finalmente, se repasan conceptos útiles para comprender mejor el mundo de la formación on line como son los conceptos entorno virtual de aprendizaje (EVA o Blended Learning (B-Learning.On line learning is a type of distance education based on new technologies. This article's aim is to introduce its main characteristics -asynchrony, non-presentiality, written communication, e-teacher role- as well as its challenges, risks, advantages and limitations. Differences between on line learning and face-to-face learning are presented in order to enable educational professionals to adapt their courses to the on line methodology. Planning and designing are introduced as key phases and, finally, useful concepts such as Virtual Learning Environment (VLE or Blended Learning (B-Learning are reviewed in order to achieve a better understanding of the on line learning field.

  9. Q-valued neural network as a system of fast identification and pattern recognition

    OpenAIRE

    Alieva, D. I.; Kryzhanovsky, B. V.; V.M. Kryzhanovsky; Fonarev, A. B.

    2004-01-01

    An effective neural network algorithm of the perceptron type is proposed. The algorithm allows us to identify strongly distorted input vector reliably. It is shown that its reliability and processing speed are orders of magnitude higher than that of full connected neural networks. The processing speed of our algorithm exceeds the one of the stack fast-access retrieval algorithm that is modified for working when there are noises in the input channel.

  10. Identification of mycobacteria and other acid fast organisms associated with pulmonary disease

    Directory of Open Access Journals (Sweden)

    Ani AE

    2011-12-01

    Full Text Available Objective: To identify Mycobacterium tuberculosis (M. tuberculosis and other acid fast organisms isolated from sputum of HIV positive adult patients with pulmonary disease in Jos, Nigeria. Methods: Acid fast organisms isolated from 80 acid fast bacilli (AFB positive sputa of HIV positive adult patients suspected for tuberculosis in Jos, Nigeria were identified for members of M. tuberculosis complex (M. tuberculosis, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti and Mycobacterium caprae by use of spoligootyping, Multiplex Gen Probe, Hain genotype assay and gene sequencing for spoligotype negative isolates. Results: Seven different spoligotypes of M. tuberculosis complex were identified from 70/80 (87.5% total number of isolates. Mycobacterium kansasii (1, Mycobacterium dulvalii (1 Nocardia species (1 and Tsukamurella species (2 were detected from 5/10 spoligotype negative isolates. Conclusions: Although M. tuberculosis is the dominant AFB associated with chronic pulmonary disease in Jos, Nigeria, other clinically relevant mycobacteria were also observed in the study. This suggests that other AFB positive microorganisms associated with tuberculosislike symptoms might be misdiagnosed and incorrectly treated as M. tuberculosis. It is therefore necessary for laboratories in tuberculosis high burden countries to step up diagnostic procedures beyond routine smear microscopy.

  11. Identification of the Bacterial Cellular Lipid Fraction by Using Fast GC × GC-MS and Innovative MS Libraries

    Science.gov (United States)

    Mondello, Luigi; Tranchida, Peter Quinto; Purcaro, Giorgia; Fanali, Chiara; Dugo, Paola; La Camera, Erminia; Bisignano, Carlo

    The bacteria fatty acid (FA) profile has been extensively studied for taxonomic classification purposes, since bacteria, in general, contain particular and rare fatty acids, compared to animal and plant tissues. In the last few years, the concern about pathogenic microorganisms used as bioterrorist agents has increased; therefore, rapid methods for the characterization of bacteria are necessary. In the present research, a half-an-hour procedure, to analyze bacteria, was developed: a 2-min one-step sample preparation step, was followed by a relatively fast comprehensive 2D GC-MS separation (25 min). Furthermore, dedicated mass spectrometry libraries were constructed for bacteria and FA identification. Finally, data-processing was carried out with the support of novel comprehensive 2D GC software.

  12. High-throughput analysis by SP-LDI-MS for fast identification of adulterations in commercial balsamic vinegars.

    Science.gov (United States)

    Guerreiro, Tatiane Melina; de Oliveira, Diogo Noin; Ferreira, Mônica Siqueira; Catharino, Rodrigo Ramos

    2014-08-01

    Balsamic vinegar (BV) is a typical and valuable Italian product, worldwide appreciated thanks to its characteristic flavors and potential health benefits. Several studies have been conducted to assess physicochemical and microbial compositions of BV, as well as its beneficial properties. Due to highly-disseminated claims of antioxidant, antihypertensive and antiglycemic properties, BV is a known target for frauds and adulterations. For that matter, product authentication, certifying its origin (region or country) and thus the processing conditions, is becoming a growing concern. Striving for fraud reduction as well as quality and safety assurance, reliable analytical strategies to rapidly evaluate BV quality are very interesting, also from an economical point of view. This work employs silica plate laser desorption/ionization mass spectrometry (SP-LDI-MS) for fast chemical profiling of commercial BV samples with protected geographical indication (PGI) and identification of its adulterated samples with low-priced vinegars, namely apple, alcohol and red/white wines.

  13. Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach

    Directory of Open Access Journals (Sweden)

    Scheres Ben

    2011-05-01

    Full Text Available Abstract Background Phenotype-driven forward genetic experiments are powerful approaches for linking phenotypes to genomic elements but they still involve a laborious positional cloning process. Although sequencing of complete genomes now becomes available, discriminating causal mutations from the enormous amounts of background variation remains a major challenge. Method To improve this, we developed a universal two-step approach, named 'fast forward genetics', which combines traditional bulk segregant techniques with targeted genomic enrichment and next-generation sequencing technology Results As a proof of principle we successfully applied this approach to two Arabidopsis mutants and identified a novel factor required for stem cell activity. Conclusion We demonstrated that the 'fast forward genetics' procedure efficiently identifies a small number of testable candidate mutations. As the approach is independent of genome size, it can be applied to any model system of interest. Furthermore, we show that experiments can be multiplexed and easily scaled for the identification of multiple individual mutants in a single sequencing run.

  14. Connecting to On-line Data

    Science.gov (United States)

    Eichhorn, G.; Astrophysics Datacenter Executive Committee (ADEC)

    2004-05-01

    The Astrophysics Datacenter Executive Committee (ADEC) is coordinating the development of a system to facilitate the linking to on-line data. This system has three components: 1. Unique dataset identifiers. 2. A verification system for identifiers. 3. Permanent links to on-line data sets. 1. The ADEC has agreed on a naming scheme for data sets that allows for the unique identification of any data set. The ADEC data centers will clearly mark their data with these identifiers to allow the generation of links to these data. 2. Each data center has a utility that can check whether a data set identifier is a valid identifier at that center. A central verifier allows third parties access to these individual verifiers through a single portal. 3. The central verifier also provides permanent links to data sets through a central link forwarding system. This makes it possible to move data sets between data centers while maintaining the permanent links. The ADEC plans to first use this system to implement the linking from the literature to on-line data in a collaboration with the AAS and the University of Chicago Press for the AAS journals.

  15. Near infrared reflectance spectroscopy for the fast identification of PVC-based films.

    Science.gov (United States)

    Laasonen, M; Rantanen, J; Harmia-Pulkkinen, T; Michiels, E; Hiltunen, R; Räsänen, M; Vuorela, H

    2001-07-01

    Near infrared (NIR) reflectance spectroscopy was used to develop a non-destructive and rapid qualitative method for the analysis of plastic films used by the pharmaceutical industry for blistering. Three types of films were investigated: 250 microm PVC [poly(vinyl chloride)] films, 250 microm PVC films coated with 40 g m(-2) of PVDC [poly(vinylidene dichloride)] and 250 microm PVC films coated with 5 g m(-2) of TE (Thermoelast) and 90 g m(-2) of PVDC. Three analyses were carried out using different pre-treatment options and a PLS (partial least squares) algorithm. Each analysis was aimed at identifying one type of film and rejecting all types of false sample (different thickness, colour or layer). True and false samples from four plastics manufacturers were included in the calibration sets in order to obtain robust methods that were suitable regardless of the supplier. Specificity was demonstrated by testing validation sets against the methods. The tests showed 0% of type I (false negative identification) and 1% of type II errors (false positive identification) for the PVC method, 13 and 3%, respectively, for the PVC-PVDC method and no error for the PVC-TE-PVDC method. Type II errors, mostly due to the slight sensitivity of the methods to film thickness, are easily corrected by simple thickness measurements. This study demonstrates that NIR spectroscopy is an excellent tool for the identification of PVC-based films. The three methods can be used by the pharmaceutical industry or plastics manufacturers for the quality control of films used in blister packaging.

  16. Identification of fast particle triggered modes by means of correlation electron cyclotron emission on Tore Supra

    Energy Technology Data Exchange (ETDEWEB)

    Goniche, M.; Huysmans, G.T.A.; Turco, F.; Maget, P.; Segui, J.L.; Artaud, J.F.; Giruzzi, G.; Imbeaux, F.; Lotte, P.; Mazon, D.; Molina, D. [CEA Cadarache, Assoc EURATOM DRFC, SCCP, F-13108 St Paul Les Durance (France); Udintsev, V.S. [EPFL /SB/CRPP, Assoc EURATOM Confederat Suisse, CH-1015 Lausanne (Switzerland)

    2008-07-01

    Low-frequency (5- to 20-kHz) and high-frequency (40- to 200-kHz) modes are studied during radio-frequency heating experiments on the Tore Supra tokamak by means of correlation electron cyclotron emission. High-frequency modes are detected when the plasma is heated by ion cyclotron range of frequency waves in the minority D(H) heating scheme in combination with lower hybrid current drive (LHCD) producing a flat or slightly reversed q-profile. They are identified as Alfven cascade modes. When this mode is triggered, fast ion losses ({<=} 20%) are detected from the neutron emission rate, and an additional heat load on plasma-facing components can be measured by an infrared camera when the fast ion energy is sufficiently large. Low-frequency modes are commonly triggered during LHCD experiments performed at low loop voltage. This mode can be observed with moderate lower hybrid power when the q-profile is monotonic or at higher power when the q-profile is flat in the core (r/a {<=} 0.2) or reversed. It is identified, in most cases, as an electron fishbone-like mode. These modes can be stabilized by a slight modification of the q-profile provided by an increase of lower hybrid power or by a small addition of electron cyclotron current device. (authors)

  17. Fast identification of folded human protein domains expressed in E. coli suitable for structural analysis

    Directory of Open Access Journals (Sweden)

    Schlegel Brigitte

    2004-03-01

    Full Text Available Abstract Background High-throughput protein structure analysis of individual protein domains requires analysis of large numbers of expression clones to identify suitable constructs for structure determination. For this purpose, methods need to be implemented for fast and reliable screening of the expressed proteins as early as possible in the overall process from cloning to structure determination. Results 88 different E. coli expression constructs for 17 human protein domains were analysed using high-throughput cloning, purification and folding analysis to obtain candidates suitable for structural analysis. After 96 deep-well microplate expression and automated protein purification, protein domains were directly analysed using 1D 1H-NMR spectroscopy. In addition, analytical hydrophobic interaction chromatography (HIC was used to detect natively folded protein. With these two analytical methods, six constructs (representing two domains were quickly identified as being well folded and suitable for structural analysis. Conclusion The described approach facilitates high-throughput structural analysis. Clones expressing natively folded proteins suitable for NMR structure determination were quickly identified upon small scale expression screening using 1D 1H-NMR and/or analytical HIC. This procedure is especially effective as a fast and inexpensive screen for the 'low hanging fruits' in structural genomics.

  18. FAST CARS: engineering a laser spectroscopic technique for rapid identification of bacterial spores.

    Science.gov (United States)

    Scully, M O; Kattawar, G W; Lucht, R P; Opatrny, T; Pilloff, H; Rebane, A; Sokolov, A V; Zubairy, M S

    2002-08-20

    Airborne contaminants, e.g., bacterial spores, are usually analyzed by time-consuming microscopic, chemical, and biological assays. Current research into real-time laser spectroscopic detectors of such contaminants is based on e.g., resonance fluorescence. The present approach derives from recent experiments in which atoms and molecules are prepared by one (or more) coherent laser(s) and probed by another set of lasers. However, generating and using maximally coherent oscillation in macromolecules having an enormous number of degrees of freedom is challenging. In particular, the short dephasing times and rapid internal conversion rates are major obstacles. However, adiabatic fast passage techniques and the ability to generate combs of phase-coherent femtosecond pulses provide tools for the generation and utilization of maximal quantum coherence in large molecules and biopolymers. We call this technique FAST CARS (femtosecond adaptive spectroscopic techniques for coherent anti-Stokes Raman spectroscopy), and the present article proposes and analyses ways in which it could be used to rapidly identify preselected molecules in real time.

  19. The SPECIES and ORGANISMS Resources for Fast and Accurate Identification of Taxonomic Names in Text

    DEFF Research Database (Denmark)

    Pafilis, Evangelos; Pletscher-Frankild, Sune; Fanini, Lucia

    2013-01-01

    The exponential growth of the biomedical literature is making the need for efficient, accurate text-mining tools increasingly clear. The identification of named biological entities in text is a central and difficult task. We have developed an efficient algorithm and implementation of a dictionary......-based approach to named entity recognition, which we here use to identify names of species and other taxa in text. The tool, SPECIES, is more than an order of magnitude faster and as accurate as existing tools. The precision and recall was assessed both on an existing gold-standard corpus and on a new corpus...

  20. Fast and reliable identification of axons, axon initial segments and dendrites with local field potential recording

    DEFF Research Database (Denmark)

    Petersen, Anders V.; Johansen, Emil O.; Perrier, Jean-Francois

    2015-01-01

    The axon initial segment (AIS) is an essential neuronal compartment. It is usually where action potentials are initiated. Recent studies demonstrated that the AIS is a plastic structure that can be regulated by neuronal activity and by the activation of metabotropic receptors. Studying the AIS...... of neurons, we can detect sinks caused by inward currents flowing across the membrane. We determine the location of the AIS by comparing the timing of these events with the action potential. We demonstrate that this method allows the unequivocal identification of the AIS of different types of neurons from...

  1. Construction of a fast ionization chamber for high-rate particle identification

    Energy Technology Data Exchange (ETDEWEB)

    Chae, K.Y., E-mail: kchae@skku.edu [Department of Physics, Sungkyunkwan University, Suwon 440-746 (Korea, Republic of); Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Ahn, S. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States); Bardayan, D.W. [Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Chipps, K.A. [Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States); Department of Physics, Colorado School of Mines, Golden, CO 80401 (United States); Manning, B. [Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854 (United States); Pain, S.D. [Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Peters, W.A. [Oak Ridge Associated Universities, Oak Ridge, TN 37831 (United States); Schmitt, K.T. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States); Smith, M.S. [Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); Strauss, S.Y. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854 (United States)

    2014-07-01

    A new gas-filled ionization chamber for high count rate particle identification has been constructed and commissioned at the Holifield Radioactive Ion Beam Facility (HRIBF) at Oak Ridge National Laboratory (ORNL). To enhance the response time of the ionization chamber, a design utilizing a tilted entrance window and tilted electrodes was adopted, which is modified from an original design by Kimura et al. [1]. A maximum counting rate of ∼700,000 particles per second has been achieved. The detector has been used for several radioactive beam measurements performed at the HRIBF.

  2. Construction of a fast ionization chamber for high-rate particle identification

    Science.gov (United States)

    Chae, K. Y.; Ahn, S.; Bardayan, D. W.; Chipps, K. A.; Manning, B.; Pain, S. D.; Peters, W. A.; Schmitt, K. T.; Smith, M. S.; Strauss, S. Y.

    2014-07-01

    A new gas-filled ionization chamber for high count rate particle identification has been constructed and commissioned at the Holifield Radioactive Ion Beam Facility (HRIBF) at Oak Ridge National Laboratory (ORNL). To enhance the response time of the ionization chamber, a design utilizing a tilted entrance window and tilted electrodes was adopted, which is modified from an original design by Kimura et al. [1]. A maximum counting rate of ~700,000 particles per second has been achieved. The detector has been used for several radioactive beam measurements performed at the HRIBF.

  3. Fast identification of digital amplitude modulation level at low signal-to-noise ratio

    Institute of Scientific and Technical Information of China (English)

    WEI Xiao-wei; CAO Zhi-gang

    2006-01-01

    In order to rapidly and automatically identify the modulation level of digital amplitude modulated signals at low signal-to-noise ratio (SNR),a method of identifying the modulation levels of M-ary quadrature amplitude modulation (M-QAM)and M-ary amplitude shift keying (M-ASK) is proposed.In this method,wavelet transform with the optimal scale is used to identify the modulation levels of M-QAM and M-ASK signals.The performance of this method was investigated through simulations.Simulation results show that when the SNR is not lower than - 4 dB,the percentage of correct identification of M-QAM is higher than 93%,and when the SNR is not lower than -10 dB,the percentage of correct identification of M-ASK is higher than 90%,using only 100 observed symbols.It shows that this method can rapidly acquire good performance at a low SNR.

  4. FAST CARS Developing a Laser Spectroscopic Technique for Rapid Identification of Bacterial Spores

    CERN Document Server

    Scully, M O; Lucht, R P; Opatrny, T; Pilloff, H; Rebane, A; Sokolov, A V; Zubairy, M S

    2002-01-01

    Airborne contaminants, e.g., bacterial spores, are usually analyzed by time consuming microscopic, chemical and biological assays. Current research into real time laser spectroscopic detectors of such contaminants is based on e.g. resonant Raman spectroscopy. The present approach derives from recent experiments in which atoms and molecules are prepared by one (or more) coherent laser(s) and probed by another set of lasers. The connection with previous studies based on "Coherent Anti-Stokes Raman Spectroscopy" (CARS) is to be noted. However generating and utilizing maximally coherent oscillation in macromolecules having an enormous number of degrees of freedom is much more challenging. This extension of the CARS technique is called FAST CARS (Femtosecond Adaptive Spectroscopic Techniques for Coherent Anti-Stokes Raman Spectroscopy), and the present paper proposes and analyses ways in which it could be used to rapidly identify pre-selected molecules in real time.

  5. Identification of the fast and thermal neutron characteristics of transuranic waste drums

    Energy Technology Data Exchange (ETDEWEB)

    Storm, B.H. Jr.; Bramblett, R.L. [Lockheed Martin Specialty Components, Largo, FL (United States); Hensley, C. [Oak Ridge National Lab., TN (United States)

    1997-11-01

    Fissile and spontaneously fissioning material in transuranic waste drums can be most sensitively assayed using an active and passive neutron assay system such as the Active Passive Neutron Examination and Assay. Both the active and the passive assays are distorted by the presence of the waste matrix and containerization. For accurate assaying, this distortion must be characterized and accounted for. An External Matrix Probe technique has been developed that accomplishes this task. Correlations between in-drum neutron flux measurements and monitors in the Active Passive Neutron Examination and Assay chamber with various matrix materials provide a non-invasive means of predicting the thermal neutron flux in waste drums. Similarly, measures of the transmission of fast neutrons emitted from sources in the drum. Results obtained using the Lockheed Martin Specialty Components Active Passive Neutron Examination and Assay system are discussed. 12 figs., 1 tab.

  6. Some aspects of analytical chemistry as applied to water quality assurance techniques for reclaimed water: The potential use of X-ray fluorescence spectrometry for automated on-line fast real-time simultaneous multi-component analysis of inorganic pollutants in reclaimed water

    Science.gov (United States)

    Ling, A. C.; Macpherson, L. H.; Rey, M.

    1981-01-01

    The potential use of isotopically excited energy dispersive X-ray fluorescence (XRF) spectrometry for automated on line fast real time (5 to 15 minutes) simultaneous multicomponent (up to 20) trace (1 to 10 parts per billion) analysis of inorganic pollutants in reclaimed water was examined. Three anionic elements (chromium 6, arsenic and selenium) were studied. The inherent lack of sensitivity of XRF spectrometry for these elements mandates use of a preconcentration technique and various methods were examined, including: several direct and indirect evaporation methods; ion exchange membranes; selective and nonselective precipitation; and complexation processes. It is shown tha XRF spectrometry itself is well suited for automated on line quality assurance, and can provide a nondestructive (and thus sample storage and repeat analysis capabilities) and particularly convenient analytical method. Further, the use of an isotopically excited energy dispersive unit (50 mCi Cd-109 source) coupled with a suitable preconcentration process can provide sufficient sensitivity to achieve the current mandated minimum levels of detection without the need for high power X-ray generating tubes.

  7. CERN Video News on line

    CERN Multimedia

    2003-01-01

    The latest CERN video news is on line. In this issue : an interview with the Director General and reports on the new home for the DELPHI barrel and the CERN firemen's spectacular training programme. There's also a vintage video news clip from 1954. See: www.cern.ch/video or Bulletin web page

  8. A Fast Robot Identification and Mapping Algorithm Based on Kinect Sensor

    Directory of Open Access Journals (Sweden)

    Liang Zhang

    2015-08-01

    Full Text Available Internet of Things (IoT is driving innovation in an ever-growing set of application domains such as intelligent processing for autonomous robots. For an autonomous robot, one grand challenge is how to sense its surrounding environment effectively. The Simultaneous Localization and Mapping with RGB-D Kinect camera sensor on robot, called RGB-D SLAM, has been developed for this purpose but some technical challenges must be addressed. Firstly, the efficiency of the algorithm cannot satisfy real-time requirements; secondly, the accuracy of the algorithm is unacceptable. In order to address these challenges, this paper proposes a set of novel improvement methods as follows. Firstly, the ORiented Brief (ORB method is used in feature detection and descriptor extraction. Secondly, a bidirectional Fast Library for Approximate Nearest Neighbors (FLANN k-Nearest Neighbor (KNN algorithm is applied to feature match. Then, the improved RANdom SAmple Consensus (RANSAC estimation method is adopted in the motion transformation. In the meantime, high precision General Iterative Closest Points (GICP is utilized to register a point cloud in the motion transformation optimization. To improve the accuracy of SLAM, the reduced dynamic covariance scaling (DCS algorithm is formulated as a global optimization problem under the G2O framework. The effectiveness of the improved algorithm has been verified by testing on standard data and comparing with the ground truth obtained on Freiburg University’s datasets. The Dr Robot X80 equipped with a Kinect camera is also applied in a building corridor to verify the correctness of the improved RGB-D SLAM algorithm. With the above experiments, it can be seen that the proposed algorithm achieves higher processing speed and better accuracy.

  9. PON-P2: prediction method for fast and reliable identification of harmful variants.

    Science.gov (United States)

    Niroula, Abhishek; Urolagin, Siddhaling; Vihinen, Mauno

    2015-01-01

    More reliable and faster prediction methods are needed to interpret enormous amounts of data generated by sequencing and genome projects. We have developed a new computational tool, PON-P2, for classification of amino acid substitutions in human proteins. The method is a machine learning-based classifier and groups the variants into pathogenic, neutral and unknown classes, on the basis of random forest probability score. PON-P2 is trained using pathogenic and neutral variants obtained from VariBench, a database for benchmark variation datasets. PON-P2 utilizes information about evolutionary conservation of sequences, physical and biochemical properties of amino acids, GO annotations and if available, functional annotations of variation sites. Extensive feature selection was performed to identify 8 informative features among altogether 622 features. PON-P2 consistently showed superior performance in comparison to existing state-of-the-art tools. In 10-fold cross-validation test, its accuracy and MCC are 0.90 and 0.80, respectively, and in the independent test, they are 0.86 and 0.71, respectively. The coverage of PON-P2 is 61.7% in the 10-fold cross-validation and 62.1% in the test dataset. PON-P2 is a powerful tool for screening harmful variants and for ranking and prioritizing experimental characterization. It is very fast making it capable of analyzing large variant datasets. PON-P2 is freely available at http://structure.bmc.lu.se/PON-P2/.

  10. A Fast Robot Identification and Mapping Algorithm Based on Kinect Sensor.

    Science.gov (United States)

    Zhang, Liang; Shen, Peiyi; Zhu, Guangming; Wei, Wei; Song, Houbing

    2015-08-14

    Internet of Things (IoT) is driving innovation in an ever-growing set of application domains such as intelligent processing for autonomous robots. For an autonomous robot, one grand challenge is how to sense its surrounding environment effectively. The Simultaneous Localization and Mapping with RGB-D Kinect camera sensor on robot, called RGB-D SLAM, has been developed for this purpose but some technical challenges must be addressed. Firstly, the efficiency of the algorithm cannot satisfy real-time requirements; secondly, the accuracy of the algorithm is unacceptable. In order to address these challenges, this paper proposes a set of novel improvement methods as follows. Firstly, the ORiented Brief (ORB) method is used in feature detection and descriptor extraction. Secondly, a bidirectional Fast Library for Approximate Nearest Neighbors (FLANN) k-Nearest Neighbor (KNN) algorithm is applied to feature match. Then, the improved RANdom SAmple Consensus (RANSAC) estimation method is adopted in the motion transformation. In the meantime, high precision General Iterative Closest Points (GICP) is utilized to register a point cloud in the motion transformation optimization. To improve the accuracy of SLAM, the reduced dynamic covariance scaling (DCS) algorithm is formulated as a global optimization problem under the G2O framework. The effectiveness of the improved algorithm has been verified by testing on standard data and comparing with the ground truth obtained on Freiburg University's datasets. The Dr Robot X80 equipped with a Kinect camera is also applied in a building corridor to verify the correctness of the improved RGB-D SLAM algorithm. With the above experiments, it can be seen that the proposed algorithm achieves higher processing speed and better accuracy.

  11. Fast reproducible identification and large-scale databasing of individual functional cognitive networks

    Directory of Open Access Journals (Sweden)

    Jobert Antoinette

    2007-10-01

    Full Text Available Abstract Background Although cognitive processes such as reading and calculation are associated with reproducible cerebral networks, inter-individual variability is considerable. Understanding the origins of this variability will require the elaboration of large multimodal databases compiling behavioral, anatomical, genetic and functional neuroimaging data over hundreds of subjects. With this goal in mind, we designed a simple and fast acquisition procedure based on a 5-minute functional magnetic resonance imaging (fMRI sequence that can be run as easily and as systematically as an anatomical scan, and is therefore used in every subject undergoing fMRI in our laboratory. This protocol captures the cerebral bases of auditory and visual perception, motor actions, reading, language comprehension and mental calculation at an individual level. Results 81 subjects were successfully scanned. Before describing inter-individual variability, we demonstrated in the present study the reliability of individual functional data obtained with this short protocol. Considering the anatomical variability, we then needed to correctly describe individual functional networks in a voxel-free space. We applied then non-voxel based methods that automatically extract main features of individual patterns of activation: group analyses performed on these individual data not only converge to those reported with a more conventional voxel-based random effect analysis, but also keep information concerning variance in location and degrees of activation across subjects. Conclusion This collection of individual fMRI data will help to describe the cerebral inter-subject variability of the correlates of some language, calculation and sensorimotor tasks. In association with demographic, anatomical, behavioral and genetic data, this protocol will serve as the cornerstone to establish a hybrid database of hundreds of subjects suitable to study the range and causes of variation in the

  12. Proteolytic Digestion and TiO2 Phosphopeptide Enrichment Microreactor for Fast MS Identification of Proteins

    Science.gov (United States)

    Deng, Jingren; Lazar, Iulia M.

    2016-04-01

    The characterization of phosphorylation state(s) of a protein is best accomplished by using isolated or enriched phosphoprotein samples or their corresponding phosphopeptides. The process is typically time-consuming as, often, a combination of analytical approaches must be used. To facilitate throughput in the study of phosphoproteins, a microreactor that enables a novel strategy for performing fast proteolytic digestion and selective phosphopeptide enrichment was developed. The microreactor was fabricated using 100 μm i.d. fused-silica capillaries packed with 1-2 mm beds of C18 and/or TiO2 particles. Proteolytic digestion-only, phosphopeptide enrichment-only, and sequential proteolytic digestion/phosphopeptide enrichment microreactors were developed and tested with standard protein mixtures. The protein samples were adsorbed on the C18 particles, quickly digested with a proteolytic enzyme infused over the adsorbed proteins, and further eluted onto the TiO2 microreactor for enrichment in phosphopeptides. A number of parameters were optimized to speed up the digestion and enrichments processes, including microreactor dimensions, sample concentrations, digestion time, flow rates, buffer compositions, and pH. The effective time for the steps of proteolytic digestion and enrichment was less than 5 min. For simple samples, such as standard protein mixtures, this approach provided equivalent or better results than conventional bench-top methods, in terms of both enzymatic digestion and selectivity. Analysis times and reagent costs were reduced ~10- to 15-fold. Preliminary analysis of cell extracts and recombinant proteins indicated the feasibility of integration of these microreactors in more advanced workflows amenable for handling real-world biological samples.

  13. Fast identification and removal of sequence contamination from genomic and metagenomic datasets.

    Directory of Open Access Journals (Sweden)

    Robert Schmieder

    Full Text Available High-throughput sequencing technologies have strongly impacted microbiology, providing a rapid and cost-effective way of generating draft genomes and exploring microbial diversity. However, sequences obtained from impure nucleic acid preparations may contain DNA from sources other than the sample. Those sequence contaminations are a serious concern to the quality of the data used for downstream analysis, causing misassembly of sequence contigs and erroneous conclusions. Therefore, the removal of sequence contaminants is a necessary and required step for all sequencing projects. We developed DeconSeq, a robust framework for the rapid, automated identification and removal of sequence contamination in longer-read datasets (150 bp mean read length. DeconSeq is publicly available as standalone and web-based versions. The results can be exported for subsequent analysis, and the databases used for the web-based version are automatically updated on a regular basis. DeconSeq categorizes possible contamination sequences, eliminates redundant hits with higher similarity to non-contaminant genomes, and provides graphical visualizations of the alignment results and classifications. Using DeconSeq, we conducted an analysis of possible human DNA contamination in 202 previously published microbial and viral metagenomes and found possible contamination in 145 (72% metagenomes with as high as 64% contaminating sequences. This new framework allows scientists to automatically detect and efficiently remove unwanted sequence contamination from their datasets while eliminating critical limitations of current methods. DeconSeq's web interface is simple and user-friendly. The standalone version allows offline analysis and integration into existing data processing pipelines. DeconSeq's results reveal whether the sequencing experiment has succeeded, whether the correct sample was sequenced, and whether the sample contains any sequence contamination from DNA preparation or

  14. Identification of Risk Factors Affecting Impaired Fasting Glucose and Diabetes in Adult Patients from Northeast China

    Directory of Open Access Journals (Sweden)

    Yutian Yin

    2015-10-01

    Full Text Available Background: Besides genetic factors, the occurrence of diabetes is influenced by lifestyles and environmental factors as well as trace elements in diet materials. Subjects with impaired fasting glucose (IFG have an increased risk of developing diabetes mellitus (DM. This study aimed to explore risk factors affecting IFG and diabetes in patients from Northeast China. Methods: A population-based, cross-sectional survey of chronic diseases and related risk factors was conducted in Jilin Province of Northeast China. All adult residents, aged 18–79, were invited to participate in this survey using the method of multistage stratified random cluster sampling. One hundred thirty-four patients with IFG or DM and 391 healthy control subjects were recruited. We compared demographic factors, body size measurements, healthy-related behaviors, and hair metallic element contents between IFG/diabetes patients and healthy individuals. Results: IFG/diabetes patients had a greater weight, waist, hip, and body mass index (BMI than control subjects. Significant differences in the content of zinc (Zn, potassium (K, copper (Ca, and sodium (Na as well as Cu/Zn ratios between IFG or DM patients and control subjects (p < 0.05 were also observed. Hair Cu, selenium (Se, and Na contents were positively correlated with blood glucose levels (Cu: rs = 0.135, p = 0.002; Se: rs = 0.110, p = 0.012; Na: rs = 0.091, p = 0.038. Polytomous logistic regression adjusting for age, sex, family history of diabetes and BMI, showed that subjects with high BMI were more likely to develop IFG and DM (IFG: OR = 1.15, OR 95% CI = 1.02–1.29; DM: OR = 1.15, OR 95% CI = 1.01–1.33. Moreover, rarely or never eating fruits was a risk factor for DM (OR = 5.46, OR 95% CI = 1.87–15.98 but not for IFG (OR = 1.70, OR 95% CI = 0.72–4.02. Subjects with abdominal obesity or DM history were more susceptible to DM (abdominal obesity: OR = 2.99, OR 95% CI = 1.07–8.37; DM history: OR = 2.69, OR 95

  15. Metabolism of cycloate in radish leaf: metabolite identification by packed capillary flow fast atom bombardment tandem mass spectrometry.

    Science.gov (United States)

    Onisko, B C; Barnes, J P; Staub, R E; Walker, F H; Kerlinger, N

    1994-10-01

    The metabolism of cycloate, a thiocarbamate herbicide, was investigated in mature radish leaf. Twelve new metabolites were identified by liquid chromatographic/mass spectrometric analysis using fast atom bombardment and packed capillary liquid chromatography columns. Full-scan and tandem mass spectrometric methods were employed. Application of the on-column focusing technique resulted in identifications with injections of as little as 15 ng of metabolite (20 ppb in radish). This injection technique allows the practical use of packed capillary liquid chromatography/mass spectrometry in sample-limited applications. Cycloate is oxidized to several ring-hydroxylated isomers that are subsequently glucosylated and esterified with malonic acid. Cycloate is also conjugated with glutathione. Metabolic hydrolysis of the glutathione conjugate formed a cysteine conjugate that is further metabolized by amidation with either malonic or acetic acid. Transamination of the cysteine conjugate gave a thiolactic acid derivative. Metabolites were also identified that were the result of both ring-hydroxylation and conjugation with glutathione. One of these, an N-acetylcysteine conjugate, is the first report of a mercapturic acid in plants. The structures of two of the new metabolites were confirmed by chemical synthesis.

  16. A Tape Method for Fast Characterization and Identification of Active Pharmaceutical Ingredients in the 2-18 THz Spectral Range

    Science.gov (United States)

    Kissi, Eric Ofosu; Bawuah, Prince; Silfsten, Pertti; Peiponen, Kai-Erik

    2015-03-01

    In order to find counterfeit drugs quickly and reliably, we have developed `tape method' a transmission spectroscopic terahertz (THz) measurement technique and compared it with a standard attenuated total reflection (ATR) THz spectroscopic measurement. We used well-known training samples, which include commercial paracetamol and aspirin tablets to check the validity of these two measurement techniques. In this study, the spectral features of some active pharmaceutical ingredients (APIs), such as aspirin and paracetamol are characterized for identification purpose. This work covers a wide THz spectral range namely, 2-18 THz. This proposed simple but novel technique, the tape method, was used for characterizing API and identifying their presence in their dosage forms. By comparing the spectra of the APIs to their dosage forms (powder samples), all distinct fingerprints present in the APIs are also present in their respective dosage forms. The positions of the spectral features obtained with the ATR techniques were akin to that obtained from the tape method. The ATR and the tape method therefore, complement each other. The presence of distinct fingerprints in this spectral range has highlighted the possibility of developing fast THz sensors for the screening of pharmaceuticals. It is worth noting that, the ATR method is applicable to flat faced tablets whereas the tape method is suitable for powders in general (e.g. curved surface tablets that require milling before measurement). Finally, we have demonstrated that ATR techniques can be used to screen counterfeit antimalarial tablets.

  17. Ultra-fast DNA-based multiplex convection PCR method for meat species identification with possible on-site applications.

    Science.gov (United States)

    Song, Kyung-Young; Hwang, Hyun Jin; Kim, Jeong Hee

    2017-08-15

    The aim of this study was to develop an ultra-fast molecular detection method for meat identification using convection Palm polymerase chain reaction (PCR). The mitochondrial cytochrome b (Cyt b) gene was used as a target gene. Amplicon size was designed to be different for beef, lamb, and pork. When these primer sets were used, each species-specific set specifically detected the target meat species in singleplex and multiplex modes in a 24min PCR run. The detection limit was 1pg of DNA for each meat species. The convection PCR method could detect as low as 1% of meat adulteration. The stability of the assay was confirmed using thermal processed meats. We also showed that direct PCR can be successfully performed with mixed meats and food samples. These results suggest that the developed assay may be useful in the authentication of meats and meat products in laboratory and rapid on-site applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Machine vision: an incremental learning system based on features derived using fast Gabor transforms for the identification of textural objects

    Science.gov (United States)

    Clark, Richard M.; Adjei, Osei; Johal, Harpal

    2001-11-01

    This paper proposes a fast, effective and also very adaptable incremental learning system for identifying textures based on features extracted from Gabor space. The Gabor transform is a useful technique for feature extraction since it exhibits properties that are similar to biologically visual sensory systems such as those found in the mammalian visual cortex. Although two-dimensional Gabor filters have been applied successfully to a variety of tasks such as text segmentation, object detection and fingerprint analysis, the work of this paper extends previous work by incorporating incremental learning to facilitate easier training. The proposed system transforms textural images into Gabor space and a non-linear threshold function is then applied to extract feature vectors that bear signatures of the textural images. The mean and variance of each training group is computed followed by a technique that uses the Kohonen network to cluster these features. The centers of these clusters form the basis of an incremental learning paradigm that allows new information to be integrated into the existing knowledge. A number of experiments are conducted for real-time identification or discrimination of textural images.

  19. Clean Air OnLine

    Energy Technology Data Exchange (ETDEWEB)

    Finney, D. [Environment Canada, Gatineau, PQ (Canada). Air Pollution Prevention Directorate

    2004-04-07

    This presentation describes Clean Air OnLine, a multi-tiered website dedicated to providing Canadians with information on air quality. The website is under development to support action to reduce air emissions, demonstrate the links between air emissions and environmental impacts, and enhance the understanding of sustainable community development issues such as health, energy, and urban sprawl. Partners in the Clean Air OnLine (CAOL) initiative include Environment Canada and the Clean Air Partnership which includes the Greater Toronto Area pilot project. The audience for CAOL includes municipal decision makers, local decision makers, community leaders, and the general public. The project provides Canadians with air pollution contextual information on pollution sources, pollutants, and related issues. It also provides information on health, environmental and economic impacts and the interrelationships with climate change issues and energy use. tabs., figs.

  20. On-line moisture analysis

    CERN Document Server

    Cutmore, N G

    2002-01-01

    Measurement of the moisture content of iron ore has become a key issue for controlling moisture additions for dust suppression. In most cases moisture content is still determined by manual or automatic sampling of the ore stream, followed by conventional laboratory analysis by oven drying. Although this procedure enables the moisture content to be routinely monitored, it is too slow for control purposes. This has generated renewed interest in on-line techniques for the accurate and rapid measurement of moisture in iron ore on conveyors. Microwave transmission techniques have emerged over the past 40 years as the dominant technology for on-line measurement of moisture in bulk materials, including iron ores. Alternative technologies have their limitations. Infra-red analysers are used in a variety of process industries, but rely on the measurement of absorption by moisture in a very thin surface layer. Consequently such probes may be compromised by particle size effects and biased presentation of the bulk mater...

  1. A commercial elemental on-line coal analyzer using pulsed neutrons

    Science.gov (United States)

    Belbot, Michael; Vouvopoulos, George; Paschal, Jonathan

    2001-07-01

    Because of its heterogeneity and the delay involved, traditional laboratory analysis of coal samples does not allow real time control of coal bulk parameters. Large excursions in important parameters (such as sulfur or calorific content) can be expensive and can be avoided with an on-line coal analyzer. The system that we developed utilizes nuclear reactions produced from fast and thermal neutrons and from neutron activation producing isotopes with half-lives longer than a few seconds. Characteristic gamma rays detected with BGO (bismuth germanate) detectors are used for the identification of the various chemical elements. The main features of the analyzer are elemental self-calibration independent of the coal seam; better accuracy in the determination of elements such as carbon, oxygen, and sodium; and diminished radiation risk. A prototype coal analyzer has been built and the first commercial model is currently being developed.

  2. Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.

    Science.gov (United States)

    Voz, Marianne L; Coppieters, Wouter; Manfroid, Isabelle; Baudhuin, Ariane; Von Berg, Virginie; Charlier, Carole; Meyer, Dirk; Driever, Wolfgang; Martial, Joseph A; Peers, Bernard

    2012-01-01

    Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the molecular lesion is still laborious and involves time-consuming genetic mapping. Here, we show that high-throughput sequencing of the whole zebrafish genome can directly locate the interval carrying the causative mutation and at the same time pinpoint the molecular lesion. The feasibility of this approach was validated by sequencing the m1045 mutant line that displays a severe hypoplasia of the exocrine pancreas. We generated 13 Gb of sequence, equivalent to an eightfold genomic coverage, from a pool of 50 mutant embryos obtained from a map-cross between the AB mutant carrier and the WIK polymorphic strain. The chromosomal region carrying the causal mutation was localized based on its unique property to display high levels of homozygosity among sequence reads as it derives exclusively from the initial AB mutated allele. We developed an algorithm identifying such a region by calculating a homozygosity score along all chromosomes. This highlighted an 8-Mb window on chromosome 5 with a score close to 1 in the m1045 mutants. The sequence analysis of all genes within this interval revealed a nonsense mutation in the snapc4 gene. Knockdown experiments confirmed the assertion that snapc4 is the gene whose mutation leads to exocrine pancreas hypoplasia. In conclusion, this study constitutes a proof-of-concept that whole-genome sequencing is a fast and effective alternative to the classical positional cloning strategies in zebrafish.

  3. Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencing.

    Directory of Open Access Journals (Sweden)

    Marianne L Voz

    Full Text Available Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identification of the molecular lesion is still laborious and involves time-consuming genetic mapping. Here, we show that high-throughput sequencing of the whole zebrafish genome can directly locate the interval carrying the causative mutation and at the same time pinpoint the molecular lesion. The feasibility of this approach was validated by sequencing the m1045 mutant line that displays a severe hypoplasia of the exocrine pancreas. We generated 13 Gb of sequence, equivalent to an eightfold genomic coverage, from a pool of 50 mutant embryos obtained from a map-cross between the AB mutant carrier and the WIK polymorphic strain. The chromosomal region carrying the causal mutation was localized based on its unique property to display high levels of homozygosity among sequence reads as it derives exclusively from the initial AB mutated allele. We developed an algorithm identifying such a region by calculating a homozygosity score along all chromosomes. This highlighted an 8-Mb window on chromosome 5 with a score close to 1 in the m1045 mutants. The sequence analysis of all genes within this interval revealed a nonsense mutation in the snapc4 gene. Knockdown experiments confirmed the assertion that snapc4 is the gene whose mutation leads to exocrine pancreas hypoplasia. In conclusion, this study constitutes a proof-of-concept that whole-genome sequencing is a fast and effective alternative to the classical positional cloning strategies in zebrafish.

  4. PHENIX on-line systems

    Energy Technology Data Exchange (ETDEWEB)

    Adler, S.S.; Allen, M.; Alley, G.; Amirikas, R.; Arai, Y.; Awes, T.C.; Barish, K.N.; Barta, F.; Batsouli, S.; Belikov, S.; Bennett, M.J.; Bobrek, M.; Boissevain, J.G.; Boose, S.; Britton, C.; Britton, L.; Bryan, W.L.; Cafferty, M.M.; Carey, T.A.; Chang, W.C.; Chi, C.Y.; Chiu, M.; Cianciolo, V.; Cole, B.A.; Constantin, P.; Cook, K.C.; Cunitz, H.; Desmond, E.J.; Ebisu, K.; Efremenko, Y.V.; El Chenawi, K.; Emery, M.S.; Engo, D.; Ericson, N.; Fields, D.E.; Frank, S.; Frantz, J.E.; Franz, A.; Frawley, A.D.; Fried, J.; Gannon, J.; Gee, T.F.; Gentry, R.; Giannotti, P.; Gustafsson, H.-A.; Haggerty, J.S.; Hahn, S.; Halliwell, J.; Hamagaki, H.; Hansen, A.G.; Hara, H.; Harder, J.; He, X.; Heistermann, F.; Hemmick, T.K.; Hibino, M.; Hill, J.C. E-mail: jhill@iastate.edu; Homma, K.; Jacak, B.V.; Jagadish, U.; Jia, J.; Kajihara, F.; Kametani, S.; Kamyshkov, Y.; Kandasamy, A.; Kang, J.H.; Kapustinsky, J.; Katou, K.; Kelley, M.A.; Kelly, S.; Kikuchi, J.; Kim, S.Y.; Kim, Y.G.; Kistenev, E.; Kotchetkov, D.; Kurita, K.; Lajoie, J.G.; Lenz, M.; Lenz, W.; Li, X.H.; Lin, S.; Liu, M.X.; Markacs, S.; Matathias, F.; Matsumoto, T.; Mead, J.; Mischke, R.E.; Mishra, G.C.; Moore, A.; Muniruzzamann, M.; Musrock, M.; Nagle, J.L.; Nandi, B.K.; Newby, J.; Nystrand, J.; O' Brien, E.; O' Connor, P.; Ohnishi, H.; Oskarsson, A.; Osterman, L.; Oyama, K.; Paffrath, L.; Pancake, C.E.; Pantuev, V.S.; Petridis, A.N.; Pisani, R.P.; Plagge, T.; Plasil, F.; Purschke, M.L.; Rankowitz, S.; Rao, R.; Rau, M.; Read, K.F.; Ryu, S.S.; Sakaguchi, T.; Sato, H.D.; Seto, R.; Shiina, T.; Silvermyr, D.; Simon-Gillo, J.; Simpson, M.; Sippach, W.; Skank, H.D.; Skutnik, S.; Sleege, G.A.; Smith, G.D.; Smith, M.; Stankus, P.W.; Steinberg, P.; Sugitate, T.; Sullivan, J.P.; Taketani, A.; Tamai, M.; Tanaka, Y.; Thomas, W.D.; Todd, R.; Toldo, F.; Turner, G.; Ushiroda, T.; Velkovska, J.; Hecke, H.W. van; Lith, M. van; Villatte, L.; Achen, W. von; Walker, J.W.; Wang, H.Q.; White, S.N.; Wintenberg, A.L.; Witzig, C.; Wood, L.[and others

    2003-03-01

    The PHENIX On-Line system takes signals from the Front End Modules (FEM) on each detector subsystem for the purpose of generating events for physics analysis. Processing of event data begins when the Data Collection Modules (DCM) receive data via fiber-optic links from the FEMs. The DCMs format and zero suppress the data and generate data packets. These packets go to the Event Builders (EvB) that assemble the events in final form. The Level-1 trigger (LVL1) generates a decision for each beam crossing and eliminates uninteresting events. The FEMs carry out all detector processing of the data so that it is delivered to the DCMs using a standard format. The FEMs also provide buffering for LVL1 trigger processing and DCM data collection. This is carried out using an architecture that is pipelined and deadtimeless. All of this is controlled by the Master Timing System (MTS) that distributes the RHIC clocks. A Level-2 trigger (LVL2) gives additional discrimination. A description of the components and operation of the PHENIX On-Line system is given and the solution to a number of electronic infrastructure problems are discussed.

  5. MALDI-TOF mass spectrometry is a fast and reliable platform for identification and ecological studies of species from family Rhizobiaceae.

    Directory of Open Access Journals (Sweden)

    Laura Ferreira

    Full Text Available Family Rhizobiaceae includes fast growing bacteria currently arranged into three genera, Rhizobium, Ensifer and Shinella, that contain pathogenic, symbiotic and saprophytic species. The identification of these species is not possible on the basis of physiological or biochemical traits and should be based on sequencing of several genes. Therefore alternative methods are necessary for rapid and reliable identification of members from family Rhizobiaceae. In this work we evaluated the suitability of Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS for this purpose. Firstly, we evaluated the capability of this methodology to differentiate among species of family Rhizobiaceae including those closely related and then we extended the database of MALDI Biotyper 2.0 including the type strains of 56 species from genera Rhizobium, Ensifer and Shinella. Secondly, we evaluated the identification potential of this methodology by using several strains isolated from different sources previously identified on the basis of their rrs, recA and atpD gene sequences. The 100% of these strains were correctly identified showing that MALDI-TOF MS is an excellent tool for identification of fast growing rhizobia applicable to large populations of isolates in ecological and taxonomic studies.

  6. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry as a tool for fast identification of protein binders in color layers of paintings.

    Science.gov (United States)

    Hynek, Radovan; Kuckova, Stepanka; Hradilova, Janka; Kodicek, Milan

    2004-01-01

    Identification of materials in color layers of paintings is necessary for correct decisions concerning restoration procedures as well as proving the authenticity of the painting. The proteins are usually important components of the painting layers. In this paper it has been demonstrated that matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) can be used for fast and reliable identification of proteins in color layers even in old, highly aged matrices. The digestion can be easily performed directly on silica wafers which are routinely used for infrared analysis. The amount of material necessary for such an analysis is extremely small. Peptide mass mapping using digestion with trypsin followed by MALDI-TOFMS and identification of the protein was successfully used for determination of the binder from a painting of the 19th century.

  7. Capture and identification of the volatile components in crude and processed herbal medicines through on-line purge and trap technique coupled with GC × GC-TOF MS.

    Science.gov (United States)

    Cao, Gang; Xu, Zhiwei; Wu, Xin; Li, Qingli; Chen, Xiaocheng

    2014-01-01

    This work aimed to investigate the volatile components in crude and processed herbal medicines (HMs). Using Atractylodis Macrocephalae Rhizoma (AMR) as a model HM, the volatile components were captured through on-line purge and trap technique and identified by using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC × GC-TOF MS) system. A total of 224 and 171 volatile compounds were identified in crude and processed AMR samples, respectively. After frying with honey-bran, 52 compounds which were found in crude AMR samples disappeared in processed AMR samples, and 15 compounds were newly generated in processed AMR. The established method can be applied in different research areas such as HM and food processing.

  8. A New Method of On-line Grid Impedance Estimation for PV Inverter

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Asiminoaei, Lucian; Blaabjerg, Frede

    2004-01-01

    for on-line measuring the grid impedance is presented. The presented method requires no extra hardware being accommodated by typical PV inverters, sensors and CPU, to provide a fast and low cost approach of on-line impedance measurement. By injecting a non-characteristic harmonic current and measuring...

  9. Rapid screening and identification of compounds with DNA-binding activity from Folium Citri Reticulatae using on-line HPLC-DAD-MS(n) coupled with a post column fluorescence detection system.

    Science.gov (United States)

    Fu, Qingrong; Zhang, Cangman; Lin, Zongtao; Sun, Hongyang; Liang, Yi; Jiang, Haixiu; Song, Zhiling; Wang, Hong; Chen, Shizhong

    2016-02-01

    To study the interactions between natural compounds and deoxyribonucleic acid (DNA), a method has been established combining a high-performance liquid chromatography-diode array detector-multi-stage mass spectrometer with a fluorescence detector (HPLC-DAD-MS(n)-FLD). The FLD was used to monitor fluorescence intensity of the ethidium bromide-DNA (EB-DNA) complex when a compound separated by HPLC was introduced. This novel method was used to simultaneously obtain the HPLC fingerprint, UV spectra, MS(n) fragments and DNA-binding activity profile of various components in Folium Citri Reticulatae. As a result, 35 compounds were identified, of which 25 were found in the extract of Folium Citri Reticulatae for the first time, and 33 compounds showed DNA-binding activities, with the most active being feruloylhexaric and p-coumaroylhexaric acids. In addition, the precision, stability and reproducibility of this method were validated by two positive controls, quercetin and hesperidin. This new on-line method is accurate, precise and reliable for further high-throughput screening of DNA-binding compounds from food samples and other complex matrices.

  10. Rapid separation and identification of 54 major constituents in Buyang Huanwu decoction by ultra-fast HPLC system coupled with DAD-TOF/MS.

    Science.gov (United States)

    Liu, E-Hu; Qi, Lian-Wen; Peng, Yong-Bo; Cheng, Xiao-Lan; Wu, Qian; Li, Ping; Li, Chang-Yin

    2009-08-01

    Buyang Huanwu Decoction (BYHWD), is a well-known traditional Chinese preparation consisting of Radix Astragali, Radix Angelicae Sinensis, Rhizoma Ligustici Chuanxiong, Radix paeoniae Rubra, Flos Carthami, Semen Persicae and Lumbricus. An ultra-fast high-performance liquid chromatography (HPLC) method coupled with diode array detection (DAD) and electrospray ionization time-of-flight mass spectrometry (ESI-TOF/MS) has been developed for rapid separation and structural identification of constituents in BYHWD. Using an ultra-fast HPLC system with short columns (4.6 x 50 mm, 1.8 microm), the total analysis time for this complex prescription is less than 30 min. With various fragmentor voltages in TOF/MS, accurate mass measurements (less than 5 ppm error) for molecular ions and characteristic fragment ions could represent reliable identification criteria for these compounds. Fifty-four major constituents from BYHWD sample, including four C-glycosyl quinochalcones, four flavonoid O-glycosides, sixteen isoflavones, six monoterpene glycosides, eight saponins, four organic acids and five amino acids, were identified or tentatively characterized based on their retention times, DAD and TOF/MS data. All the compounds were further assigned in the seven individual crude drugs. In conclusion, the ultra-fast HPLC with DAD-TOF/MS is a highly useful and efficient technique to separate and identify constituents in complex matrices of herbal medicines or preparations.

  11. The Effects of Practicing with a Virtual Ultrasound Trainer on FAST Window Identification, Acquisition, and Diagnosis. CRESST Report 787

    Science.gov (United States)

    Chung, Gregory K. W. K.; Gyllenhammer, Ruth G.; Baker, Eva L.

    2011-01-01

    In this study, we compared the effects of simulator-based virtual ultrasound scanning practice to classroom-based hands-on ultrasound scanning practice on participants' knowledge of FAST window quadrants and interpretation, and on participants' performance on live patient FAST exams. Twenty-five novice participants were randomly assigned to the…

  12. Enhancing On-Line Teaching with Verbal Immediacy through Self-Determination Theory

    Science.gov (United States)

    Furlich, Stephen A.

    2013-01-01

    This paper explores the use of instructor verbal immediacy behaviors for on-line classes. Specifically, it demonstrates how instructor verbal immediacy behaviors found in face-to-face classes can also be displayed for on-line classes. It is argued that self-determination theory describes identification of the student as an important role in the…

  13. Use of fast multivariant identification of the parameters of adsorption systems to study the impact of activating agent on microporous structure formation during activation.

    Science.gov (United States)

    Kwiatkowski, Mirosław

    2009-12-01

    The possibility of using fast multivariant identification of adsorption system parameters to evaluate the influence of the activation conditions on the microporous structure of carbonaceous adsorbents was examined. The fitted models used in the procedure are based on a unique approach to the modeling of adsorption processes, which is a significant development of the conventional BET approach. This takes into account the occurrence of branched clusters and surface heterogeneity. The approach considers heterogeneity from the perspectives of both geometry and energy, and discusses geometrical and energy limitations of creating clusters and the adhesive forces in layers above the first one.

  14. Competitive binding-based optical DNA mapping for fast identification of bacteria--multi-ligand transfer matrix theory and experimental applications on Escherichia coli.

    Science.gov (United States)

    Nilsson, Adam N; Emilsson, Gustav; Nyberg, Lena K; Noble, Charleston; Stadler, Liselott Svensson; Fritzsche, Joachim; Moore, Edward R B; Tegenfeldt, Jonas O; Ambjörnsson, Tobias; Westerlund, Fredrik

    2014-09-01

    We demonstrate a single DNA molecule optical mapping assay able to resolve a specific Escherichia coli strain from other strains. The assay is based on competitive binding of the fluorescent dye YOYO-1 and the AT-specific antibiotic netropsin. The optical map is visualized by stretching the DNA molecules in nanofluidic channels. We optimize the experimental conditions to obtain reproducible barcodes containing as much information as possible. We implement a multi-ligand transfer matrix method for calculating theoretical barcodes from known DNA sequences. Our method extends previous theoretical approaches for competitive binding of two types of ligands to many types of ligands and introduces a recursive approach that allows long barcodes to be calculated with standard computer floating point formats. The identification of a specific E. coli strain (CCUG 10979) is based on mapping of 50-160 kilobasepair experimental DNA fragments onto the theoretical genome using the developed theory. Our identification protocol introduces two theoretical constructs: a P-value for a best experiment-theory match and an information score threshold. The developed methods provide a novel optical mapping toolbox for identification of bacterial species and strains. The protocol does not require cultivation of bacteria or DNA amplification, which allows for ultra-fast identification of bacterial pathogens.

  15. Competitive binding-based optical DNA mapping for fast identification of bacteria - multi-ligand transfer matrix theory and experimental applications on Escherichia coli

    Science.gov (United States)

    Nilsson, Adam N.; Emilsson, Gustav; Nyberg, Lena K.; Noble, Charleston; Stadler, Liselott Svensson; Fritzsche, Joachim; Moore, Edward R. B.; Tegenfeldt, Jonas O.; Ambjörnsson, Tobias; Westerlund, Fredrik

    2014-01-01

    We demonstrate a single DNA molecule optical mapping assay able to resolve a specific Escherichia coli strain from other strains. The assay is based on competitive binding of the fluorescent dye YOYO-1 and the AT-specific antibiotic netropsin. The optical map is visualized by stretching the DNA molecules in nanofluidic channels. We optimize the experimental conditions to obtain reproducible barcodes containing as much information as possible. We implement a multi-ligand transfer matrix method for calculating theoretical barcodes from known DNA sequences. Our method extends previous theoretical approaches for competitive binding of two types of ligands to many types of ligands and introduces a recursive approach that allows long barcodes to be calculated with standard computer floating point formats. The identification of a specific E. coli strain (CCUG 10979) is based on mapping of 50–160 kilobasepair experimental DNA fragments onto the theoretical genome using the developed theory. Our identification protocol introduces two theoretical constructs: a P-value for a best experiment-theory match and an information score threshold. The developed methods provide a novel optical mapping toolbox for identification of bacterial species and strains. The protocol does not require cultivation of bacteria or DNA amplification, which allows for ultra-fast identification of bacterial pathogens. PMID:25013180

  16. Are on-line currencies virtual banknotes?

    OpenAIRE

    Stephen F. Quinn; William Roberds

    2003-01-01

    The history of money is marked by innovations that have expanded the role of "inside money"-money created by the private sector. For instance, the past few years have seen the development of several types of on-line payment arrangements, some of which have been dubbed "on-line currencies." ; This article examines the likely success or failure of on-line currencies by means of a historical analogy. The discussion compares the introduction of on-line currencies to the debut of the bearer bankno...

  17. 基于支持向量机的快速核素识别方法研究%The Study of Fast Nuclide Identification Method with SVM

    Institute of Scientific and Technical Information of China (English)

    谢先博; 张晖

    2014-01-01

    针对传统γ能谱核素识别算法在较低放射性水平下的情况下存在核素识别慢,对相干核素识别效果差的问题,基于统计学习理论提出了基于支持向量机的快速核素识别方法。本方法一方面通过对峰位确定方法改进来提高特征量提取的精确度,去除γ能谱中重叠峰对相干核素识别中的影响,另一方面使用支持向量机方法实现核素的快速分类。通过与传统方法的比对,新方法在识别相干核素方面达到了很好的识别效果。%Nuclide identification algorithm for energy spectrum at low level radioactive nuclide identification exits slow, poor re-sults on coherent radionuclide identification problem.based on statistical learning theory proposed based on support vector ma-chine quick radionuclide identification method. By this method one hand, spectrum data smoothing, peak position to determine ways to improve to improve the accuracy of feature extraction, removal of overlapping peaks in spectra for radionuclide identifica-tion of coherent effects, on the other hand using the support vector machine approach to nuclear prime fast classification. By com-parison with the traditional methods, the new method in identifying coherent nuclide has reached a good recognition results.

  18. Evaluation of the Accelerate Pheno System for Fast Identification and Antimicrobial Susceptibility Testing from Positive Blood Cultures in Bloodstream Infections Caused by Gram-Negative Pathogens.

    Science.gov (United States)

    Marschal, Matthias; Bachmaier, Johanna; Autenrieth, Ingo; Oberhettinger, Philipp; Willmann, Matthias; Peter, Silke

    2017-07-01

    Bloodstream infections (BSI) are an important cause of morbidity and mortality. Increasing rates of antimicrobial-resistant pathogens limit treatment options, prompting an empirical use of broad-range antibiotics. Fast and reliable diagnostic tools are needed to provide adequate therapy in a timely manner and to enable a de-escalation of treatment. The Accelerate Pheno system (Accelerate Diagnostics, USA) is a fully automated test system that performs both identification and antimicrobial susceptibility testing (AST) directly from positive blood cultures within approximately 7 h. In total, 115 episodes of BSI with Gram-negative bacteria were included in our study and compared to conventional culture-based methods. The Accelerate Pheno system correctly identified 88.7% (102 of 115) of all BSI episodes and 97.1% (102 of 105) of isolates that are covered by the system's identification panel. The Accelerate Pheno system generated an AST result for 91.3% (95 of 104) samples in which the Accelerate Pheno system identified a Gram-negative pathogen. The overall category agreement between the Accelerate Pheno system and culture-based AST was 96.4%, the rates for minor discrepancies 1.4%, major discrepancies 2.3%, and very major discrepancies 1.0%. Of note, ceftriaxone, piperacillin-tazobactam, and carbapenem resistance was correctly detected in blood culture specimens with extended-spectrum beta-lactamase-producing Escherichia coli (n = 7) and multidrug-resistant Pseudomonas aeruginosa (n = 3) strains. The utilization of the Accelerate Pheno system reduced the time to result for identification by 27.49 h (P based methods in our laboratory setting. In conclusion, the Accelerate Pheno system provided fast, reliable results while significantly improving turnaround time in blood culture diagnostics of Gram-negative BSI. Copyright © 2017 American Society for Microbiology.

  19. A Study of the Impact of the on the Accuracy of On-Line Raw Structure of Item Bank Item Attribute Identification%题库结构对原始题在线属性标定准确性之影响研究

    Institute of Scientific and Technical Information of China (English)

    汪文义; 丁树良

    2012-01-01

    目前已有研究证明可达阵在认知诊断测验编制中起重要作用,但迄今为止并没有引起普遍注意。本文主要讨论当题库缺少可达阵对应的某些项目类,对原始题的属性向量在线标定的准确性的影响。本文对含6个属性的独立型结构进行了模拟试验,结果显示:如果题库不充要,原始题的属性标定准确性受到影响,题库中非可达阵中项目对标定有一定的弥补作用。间接印证了可达阵在认知诊断题库起到非常重要的作用。%Cognitive Diagnostic Assessment is based on the incidence Q-matrix (Tatsuoka, 2009). The entries of Q-matrix indicate which skills and knowledge are involved in the solution of each item. In real situations, no matter whether the items have or have not been identified attributes before its construction, it will cost a lot of money, require more efforts to identify attributes through specialists according to the special procedure and yet can' t completely assume the correctness due to the subjectivity. On-line item attributes iden- tification as a new field and study of the impact of item bank hasn' t been found in the literature. So this study is concerned with the impact of item bank on on-line item attributes identification in cognitive diagnostic computerized adaptive testing ( CD-CAT), especially when the item bank doesn' t include the whole reachability matrix. The study describes the impact of knowledge states' equivalent classes on the item attributes vectors ' equivalent classes. Some of those are called the discriminating item attribute vector when the item attribute vectors' equivalent classes only include one item attribute vector; the others are called indiscriminate item attribute vector. Moreover, the study introduces the Marginal Maximum Likelihood Estimation (MMLE) for on-line item attribute identification, which integrates the uncertainty of estimate knowledge states in the procedure

  20. Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction.

    Science.gov (United States)

    Mujezinovic, Nedim; Schneider, Georg; Wildpaner, Michael; Mechtler, Karl; Eisenhaber, Frank

    2010-02-10

    Tandem mass spectrometry (MS/MS) has become a standard method for identification of proteins extracted from biological samples but the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, a minor fraction of the spectra per sample (most often, only a few %) and about 10% of the peaks per spectrum contribute to the final result if protein identification is not prevented by the noise at all. Two fast preprocessing screens can substantially reduce the haystack of MS/MS data. (1) Simple sequence ladder rules remove spectra non-interpretable in peptide sequences. (2) Modified Fourier-transform-based criteria clear background in the remaining data. In average, only a remainder of 35% of the MS/MS spectra (each reduced in size by about one quarter) has to be handed over to the interpretation software for reliable protein identification essentially without loss of information, with a trend to improved sequence coverage and with proportional decrease of computer resource consumption. The search for sequence ladders in tandem MS/MS spectra with subsequent noise suppression is a promising strategy to reduce the number of MS/MS spectra from electro-spray instruments and to enhance the reliability of protein matches. Supplementary material and the software are available from an accompanying WWW-site with the URL http://mendel.bii.a-star.edu.sg/mass-spectrometry/MSCleaner-2.0/.

  1. On-line Dynamic Security Assessment in Power Systems

    DEFF Research Database (Denmark)

    Weckesser, Johannes Tilman Gabriel

    tools may no longer be feasible, since they are generally based on extensive off-line studies. A core component of an efficient on-line dynamic security assessment is a fast and reliable contingency screening. As part of this thesis a contingency screening method is developed and its performance......The thesis concerns the development of tools and methods for on-line dynamic security assessment (DSA). In a future power system with low-dependence or even independence of fossil fuels, generation will be based to a large extent on noncontrollable renewable energy sources (RES), such as wind...... and solar radiation. Moreover, ongoing research suggests that demand response will be introduced to maintain power balance between generation and consumption at all times. Due to these changes the operating point of the power system will be less predictable and today’s stability and security assessment...

  2. On-Line Real Time Realization and Application of Adaptive Fuzzy Inference Neural Network

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In this paper,a modeling algorithm developed by transferring the adaptive fuzzy inference neural network into an on-line real time algorithm,combining the algorithm with conventional system identification method and applying them to separate identification of nonlinear mu Iti-variable systems is introduced and discussed.

  3. Research on Method of Fast Identification and Diagnosis for Transmission Attitude of Explosive Roll%药卷传输姿态快速识别与诊断方法研究

    Institute of Scientific and Technical Information of China (English)

    何传龙; 何小敏; 许亮; 黄志平

    2012-01-01

    工业炸药包装过程中,药卷传输姿态异常会影响后续工序;针对药卷传送皮带快速运动的特点,提出基于机器视觉的药卷传输姿态快速识别与诊断方法;该方法经过图像预处理,提取与药卷中轴线平行的药卷边缘直线,计算出药卷传输姿态的夹角θ,再由θ诊断药卷传输姿态;在搭建的仿真平台上,利用OpenCV开发仿真实验程序;实验结果表明,文中的方法每帧图像检测速度比药卷传输速度快4.8倍,可满足在线检测药卷传输姿态的要求.%In the industrial explosive packaging process, the abnormal posture of explosive roll transmission attitude will affect the follow - up process. For the transmission attitude of explosive roll on the fast movement conveyer belt, a fast method of identification and diagnosis based on machine vision is proposed. In our proposed method, after an image preprocessed, the edge lines of explosive roll which parallel to its central axis is extracted from the image. Then the angle 0 of roll transmission attitude is calculated. And its transmission attitude is identified. In our simulation platform. We use OpenCV for a experiment simulation program to come the proposed method true. The experiment results show that the detection speed of each frame image is 4. 8 times faster than the actual explosive roll transfers using this method. This situation can meet the requirements of on- line detection for the roll transmission attitude.

  4. On line routing per mobile phone

    DEFF Research Database (Denmark)

    Bieding, Thomas; Görtz, Simon; Klose, Andreas

    2009-01-01

    On-line routing is concerned with building vehicle routes in an ongoing fashion in such a way that customer requests arriving dynamically in time are efficiently and effectively served. An indispensable prerequisite for applying on-line routing methods is mobile communication technology. Addition...

  5. Simulation and prototyping of 2 m long resistive plate chambers for detection of fast neutrons and multi-neutron event identification

    Energy Technology Data Exchange (ETDEWEB)

    Elekes, Z., E-mail: z.elekes@hzdr.de [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Aumann, T. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Technische Universität Darmstadt, Darmstadt (Germany); Bemmerer, D. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Boretzky, K. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Caesar, C. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Technische Universität Darmstadt, Darmstadt (Germany); Cowan, T.C. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Technische Universität Dresden, Dresden (Germany); Hehner, J.; Heil, M. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Kempe, M. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Rossi, D. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Röder, M. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Technische Universität Dresden, Dresden (Germany); Simon, H. [GSI Helmholtzzentrumfür Schwerionenforschung, Darmstadt (Germany); Sobiella, M.; Stach, D. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Reinhardt, T. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Technische Universität Dresden, Dresden (Germany); Wagner, A.; Yakorev, D. [Helmholtz-Zentrum Dresden-Rossendorf, Dresden (Germany); Zilges, A. [Universität zu Köln, Köln (Germany); Zuber, K. [Technische Universität Dresden, Dresden (Germany)

    2013-02-11

    Resistive plate chamber (RPC) prototypes of 2 m length were simulated and built. The experimental tests using a 31 MeV electron beam, discussed in details, showed an efficiency higher than 90% and an excellent time resolution of around σ=100ps. Furthermore, comprehensive simulations were performed by GEANT4 toolkit in order to study the possible use of these RPCs for fast neutron (200 MeV–1 GeV) detection and multi-neutron event identification. The validation of simulation parameters was carried out via a comparison to experimental data. A possible setup for invariant mass spectroscopy of multi-neutron emission is presented and the characteristics are discussed. The results show that the setup has a high detection efficiency. Its capability of determining the momentum of the outgoing neutrons and reconstructing the relative energy between the fragments from nuclear reactions is demonstrated for different scenarios.

  6. On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study

    Directory of Open Access Journals (Sweden)

    Taoran Li

    2010-01-01

    Full Text Available The purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART system for prostate cancer treatment based on daily cone-beam CT imaging and fast volumetric reoptimization of treatment plans. A fast intensity-modulated radiotherapy (IMRT plan reoptimization algorithm is implemented and evaluated with clinical cases. The quality of these adapted plans is compared to the corresponding new plans generated by an experienced planner using a commercial treatment planning system and also evaluated by an in-house developed tool estimating achievable dose-volume histograms (DVHs based on a database of existing treatment plans. In addition, a clinical implementation scheme for ART is designed and evaluated using clinical cases for its dosimetric qualities and efficiency.

  7. On-line battery identification for electric driving range prediction

    NARCIS (Netherlands)

    Kessels, J.T.B.A.; Rosca, B.; Bergveld, H.J.; Bosch, P.P.J. van den

    2011-01-01

    Hybrid and electric vehicles require accurate knowledge of the battery to make an educated guess about the expected electric driving range. Range prediction is complicated by the fact that batteries are subject to external influences and aging. Also the future driving behavior is often unknown. This

  8. On-line battery identification for electric driving range prediction

    NARCIS (Netherlands)

    Kessels, J.T.B.A.; Rosca, B.; Bergveld, H.J.; Bosch, P.P.J. van den

    2011-01-01

    Hybrid and electric vehicles require accurate knowledge of the battery to make an educated guess about the expected electric driving range. Range prediction is complicated by the fact that batteries are subject to external influences and aging. Also the future driving behavior is often unknown. This

  9. On-line generalized Steiner problem

    Energy Technology Data Exchange (ETDEWEB)

    Awerbuch, B.; Azar, Y.; Bartal, Y. [Tel Aviv Univ. (Israel)

    1996-12-31

    The Generalized Steiner Problem (GSP) is defined as follows. We are given a graph with non-negative weights and a set of pairs of vertices. The algorithm has to construct minimum weight subgraph such that the two nodes of each pair are connected by a path. We consider the on-line generalized Steiner problem, in which pairs of vertices arrive on-line and are needed to be connected immediately. We give a simple O(log{sup 2} n) competitive deterministic on-line algorithm. The previous best online algorithm (by Westbrook and Yan) was O({radical}n log n) competitive. We also consider the network connectivity leasing problem which is a generalization of the GSP. Here edges of the graph can be either bought or leased for different costs. We provide simple randomized O(log{sup 2} n) competitive algorithm based on the on-line generalized Steiner problem result.

  10. The war against on-line piracy

    OpenAIRE

    Harris, Julian

    2011-01-01

    A summary by Julian Harris, Deputy General Editor Amicus Curiae, of US attempts to control what it identifies as rogue Internet sites engaged in on-line piracy and opposition to such legislative moves.

  11. Optimization and validation of a fast amplification protocol for AmpFlSTR® Profiler Plus® for rapid forensic human identification.

    Science.gov (United States)

    Laurin, Nancy; Frégeau, Chantal

    2012-01-01

    The goal of this work was to optimize and validate a fast amplification protocol for the multiplex amplification of the STR loci included in AmpFlSTR(®) Profiler Plus(®) to expedite human DNA identification. By modifying the cycling conditions and by combining the use of a DNA polymerase optimized for high speed PCR (SpeedSTAR™ HS) and a more efficient thermal cycler instrument (Bio-RAD C1000™), we were able to reduce the amplification process from 4h to 26 min. No modification to the commercial AmpFlSTR(®) Profiler Plus(®) primer mix was required. When compared to the current Royal Canadian Mounted Police (RCMP) amplification protocol, no differences with regards to specificity, sensitivity, heterozygote peak height ratios and overall profile balance were noted. Moreover, complete concordance was obtained with profiles previously generated with the standard amplification protocol and minor alleles in mixture samples were reliably typed. An increase in n-4 stutter ratios (2.2% on average for all loci) was observed for profiles amplified with the fast protocol compared to the current procedure. Our results document the robustness of this rapid amplification protocol for STR profiling using the AmpFlSTR(®) Profiler Plus(®) primer set and demonstrate that comparable data can be obtained in substantially less time. This new approach could provide an alternative option to current multiplex STR typing amplification protocols in order to increase throughput or expedite time-sensitive cases.

  12. On-Line Acquisitions by LOLITA

    Directory of Open Access Journals (Sweden)

    Frances G. Spigai

    1970-12-01

    Full Text Available The on-line acquisition program (LOLITA in use at the Oregon State University Library is described in terms of development costs, equipment requirements, and overall design philosophy. In particular, the record format and content of records in the on-order file, and the on-line processing of these records (input, search, correction, output using a cathode ray tube display terminal are detailed.

  13. ACSEPP On-Line Electronic Payment Protocol

    Institute of Scientific and Technical Information of China (English)

    WANG Shao-bin; ZHU Xian; HONG Fan

    2004-01-01

    With analyzing the existing on-line electronic payment protocols, this paper presents a new on-line electronic payment protocol named ACSEPP: Anonymous, Convenient and Secure Electronic Payment Protocol.Its aim is to design a practical electronic payment protocol which is both secure and convenient.Without using PKI_CA frame, it realized the anonymity of consumer and merchant, the convenient of handling, the low cost of maintenance and the security.

  14. Fast and sensitive alignment of microbial whole genome sequencing reads to large sequence datasets on a desktop PC: application to metagenomic datasets and pathogen identification.

    Directory of Open Access Journals (Sweden)

    Lőrinc S Pongor

    Full Text Available Next generation sequencing (NGS of metagenomic samples is becoming a standard approach to detect individual species or pathogenic strains of microorganisms. Computer programs used in the NGS community have to balance between speed and sensitivity and as a result, species or strain level identification is often inaccurate and low abundance pathogens can sometimes be missed. We have developed Taxoner, an open source, taxon assignment pipeline that includes a fast aligner (e.g. Bowtie2 and a comprehensive DNA sequence database. We tested the program on simulated datasets as well as experimental data from Illumina, IonTorrent, and Roche 454 sequencing platforms. We found that Taxoner performs as well as, and often better than BLAST, but requires two orders of magnitude less running time meaning that it can be run on desktop or laptop computers. Taxoner is slower than the approaches that use small marker databases but is more sensitive due the comprehensive reference database. In addition, it can be easily tuned to specific applications using small tailored databases. When applied to metagenomic datasets, Taxoner can provide a functional summary of the genes mapped and can provide strain level identification. Taxoner is written in C for Linux operating systems. The code and documentation are available for research applications at http://code.google.com/p/taxoner.

  15. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Fast and Accurate Identification of Cross-Linked Peptides for the structural analysis of large protein complexes and to elucidate interaction networks. Salman Tahir Jimi-Carlo Bukowski-Wills; Morten Rasmussen; Juri RappsilberWellcome Trust Centre for Cell Biology, Edinburgh , United Kingdom   Novel...

  16. Sensorless Control Technique of PMSG for Wind Power Application Based on On-line Parameter Identification%基于参数在线辨识的永磁风力发电机无位置传感器控制技术

    Institute of Scientific and Technical Information of China (English)

    年珩; 李嘉文; 万中奇

    2012-01-01

    提出一种基于无位置传感器及电机参数在线辨识的永磁同步风力发电机控制策略。通过建立永磁同步发电机的扩展反电势数学模型,推导出基于锁相环技术的转子位置自检测控制模型。为消除发电机参数时变性对转子位置观测精度的影响,建立了基于递归最小二乘法的电机参数辨识模型,对永磁风力发电机的d、q轴电感进行实时在线辨识,并将实时辨识得到的电机参数应用于发电机转子位置观测和转子磁场定向矢量控制中。建立了一套2kW的永磁风力发电机实验机组,对所提控制策略的有效性和可行性进行了实验验证。%A novel position sensorless control strategy integrated with the on-line parameter identification for a permanent magnet synchronous generator(PMSG) applied to wind power generation was proposed in the paper.Based on PMSG mathematic model,the phase-locked loop technique was used to detect the rotor position.Considering that the position detection accuracy was influenced by the generator parameter variation,the recursive least square algorithm was adapted for PMSG inductance parameters identification.Then,the rotor position and PMSG parameters obtained based on the proposed method were used in the rotor-flux oriented vector control of PMSG for wind power generation system.Experiment on a 2 kW PMSG-based prototype demonstrates that the proposed method is effective and is capable of achieving more accurate control than the generation system without parameter identification.

  17. Colorimetric sensor array allows fast detection and simultaneous identification of sepsis-causing bacteria in spiked blood culture.

    Science.gov (United States)

    Lim, Sung H; Mix, Samantha; Xu, Zeyu; Taba, Brian; Budvytiene, Indre; Berliner, Anders N; Queralto, Nuria; Churi, Yair S; Huang, Richard S; Eiden, Michael; Martino, Raymond A; Rhodes, Paul; Banaei, Niaz

    2014-02-01

    Sepsis is a medical emergency demanding early diagnosis and tailored antimicrobial therapy. Every hour of delay in initiating effective therapy measurably increases patient mortality. Blood culture is currently the reference standard for detecting bloodstream infection, a multistep process which may take one to several days. Here, we report a novel paradigm for earlier detection and the simultaneous identification of pathogens in spiked blood cultures by means of a metabolomic "fingerprint" of the volatile mixture outgassed by the organisms. The colorimetric sensor array provided significantly faster detection of positive blood cultures than a conventional blood culture system (12.1 h versus 14.9 h, P detection. The colorimetric sensor array also allowed for discrimination between unrelated strains of methicillin-resistant Staphylococcus aureus, indicating that the metabolomic fingerprint has the potential to track nosocomial transmissions. Altogether, the colorimetric sensor array is a promising tool that offers a new paradigm for diagnosing bloodstream infections.

  18. Formación on line

    Directory of Open Access Journals (Sweden)

    O. Grau-Perejoan

    Full Text Available La formación on line es una modalidad de enseñanza a distancia basada en las nuevas tecnologías. En este artículo se pretende hacer una introducción a base de describir a grandes rasgos sus características principales: asincronía, no presencialidad, comunicación escrita, función del profesor on line, así como los retos, los riesgos, las ventajas y los inconvenientes que plantea. Se exponen las diferencias entre la formación on line y la formación presencial, de manera que los docentes puedan adaptar de la mejor manera posible sus propuestas formativas a la modalidad on line. Se introduce el importantísimo papel de la planificación y de la fase de diseño y, finalmente, se repasan conceptos útiles para comprender mejor el mundo de la formación on line como son los conceptos entorno virtual de aprendizaje (EVA o Blended Learning (B-Learning.

  19. [Fast separation and identification of nine carcinogenic dyes in textiles using liquid chromatography-electrospray tandem mass spectrometry].

    Science.gov (United States)

    Ding, Youchao; Cao, Xizhong; Wu, Lina; Zhang, Qian

    2008-09-01

    A qualitative method of the identification of nine carcinogenic dyes prohibited in textiles was developed using high performance liquid chromatography-tandem mass spectrometry interfaced with electro-spray ionization (HPLC-ESI-MS/MS) in the selective reaction monitoring (SRM) mode. The dyes were extracted from textiles composed of natural or chemical fibers by methanol under ultrasounication, and then eluted with gradient by acetonitrile and 5 mmol/L ammonium acetate from an RP-C18 column with two segments in effluents. The first effluents accommodated Acid Red 26, Direct Blue 6, Direct Black 38 and Direct Red 28 with negative ionization mode, while the second accommodated Basic Red 9, Basic Violet 14, Disperse Blue 1, Disperse Orange 11 and Disperse Yellow 3 with positive ionization mode. Thus the investigated compounds could be identified simultaneously with single-run analysis no matter which type of the fibre the sample was and no matter which category of the dye the analyte was. The established method was successfully applied to identify the carcinogenic dyes in textile samples through comparing the chromatographic retention time and the relative abundance of characteristic product ions with the standards.

  20. SISP: a Fast Species Identification System for Prokaryotes Based on Total Nucleotide Identity of Whole Genome Sequences

    Directory of Open Access Journals (Sweden)

    Jiapeng Chen

    2015-06-01

    Full Text Available In the genomic era, new techniques and criteria are proposed to improve the traditionally phenotypic and biochemical test–based approaches for prokaryotic species definition. Among them, average nucleotide identity (ANI mirrors DNA-DNA hybridization and is widely used by the microbial research community. However, our test shows that ANI possibly defines distinct taxa as the same species when they shared highly homologous sequences in a very short genomic region. In this study, we propose an improved algorithm named total nucleotide identity (TNI for use in bacterial taxonomy; this algorithm provided higher accuracy for species classification than ANI. Furthermore, we developed a species identification system for prokaryotes (SISP based on pairwise TNI of 3,073 genomes acquired from GenBank. For a submitted query genome, SISP can quickly find its most closely related genome from the established database based on the TNI calculation and infer the possible species of the query genome. Given a criterion of TNI > 70%, SISP has an accuracy that was above 90% for 3,596 prokaryotic genomes. SISP is open source and is available at https://github.com/chjp/SISProkaryotes.

  1. On line routing per mobile phone

    DEFF Research Database (Denmark)

    Bieding, Thomas; Görtz, Simon; Klose, Andreas

    2009-01-01

    . Additionally it is of utmost importance that the employed communication system is suitable integrated with the firm’s enterprise application system and business processes. On basis of a case study, we describe in this paper a system that is cheap and easy to implement due to the use of simple mobile phones......On-line routing is concerned with building vehicle routes in an ongoing fashion in such a way that customer requests arriving dynamically in time are efficiently and effectively served. An indispensable prerequisite for applying on-line routing methods is mobile communication technology...

  2. Educational On-Line Gaming Propensity

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana; Kirchner, Kathrin

    2014-01-01

    Educational on-line games are promising for new generations of students who are grown up digital. Th e new generations of students are technology savvy and spend lots of time on the web and on social networks. Based on an exploratory study, this article investigates the factors that infl uence...... students’ willingness to participate in serious games for teaching/learning. Th is study investigates the relationship between students’ behavior on Facebook, Facebook games, and their attitude toward educational on-line games. Th e results of the study reveal that the early adopters of educational games...

  3. Identification of a large, fast-expanding HIV-1 subtype B transmission cluster among MSM in Valencia, Spain

    Science.gov (United States)

    Patiño-Galindo, Juan Ángel; Torres-Puente, Manoli; Bracho, María Alma; Alastrué, Ignacio; Juan, Amparo; Navarro, David; Galindo, María José; Gimeno, Concepción; Ortega, Enrique

    2017-01-01

    We describe and characterize an exceptionally large HIV-1 subtype B transmission cluster occurring in the Comunidad Valenciana (CV, Spain). A total of 1806 HIV-1 protease-reverse transcriptase (PR/RT) sequences from different patients were obtained in the CV between 2004 and 2014. After subtyping and generating a phylogenetic tree with additional HIV-1 subtype B sequences, a very large transmission cluster which included almost exclusively sequences from the CV was detected (n = 143 patients). This cluster was then validated and characterized with further maximum-likelihood phylogenetic analyses and Bayesian coalescent reconstructions. With these analyses, the CV cluster was delimited to 113 patients, predominately men who have sex with men (MSM). Although it was significantly located in the city of Valencia (n = 105), phylogenetic analyses suggested this cluster derives from a larger HIV lineage affecting other Spanish localities (n = 194). Coalescent analyses estimated its expansion in Valencia to have started between 1998 and 2004. From 2004 to 2009, members of this cluster represented only 1.46% of the HIV-1 subtype B samples studied in Valencia (n = 5/143), whereas from 2010 onwards its prevalence raised to 12.64% (n = 100/791). In conclusion, we have detected a very large transmission cluster in the CV where it has experienced a very fast growth in the recent years in the city of Valencia, thus contributing significantly to the HIV epidemic in this locality. Its transmission efficiency evidences shortcomings in HIV control measures in Spain and particularly in Valencia. PMID:28152089

  4. ON-LINE DOCUMENTS CONTENT MANAGEMENT

    Directory of Open Access Journals (Sweden)

    VASILESCU RAMONA VIOLETA

    2010-05-01

    Full Text Available This paper outlines the steps and technologies used in developing an on-line application server with many desktop clients, and with high power processing for a wide range of input documents to obtain searchable documents on the highest portability standards, PDF and PDF /A.

  5. A P2P approach to resource discovery in on-line monitoring of Grid workflows

    NARCIS (Netherlands)

    Łabno, B.; Bubak, M.; Baliś, B.

    2008-01-01

    On-line monitoring of Grid workflows is challenging since workflows are loosely coupled and highly dynamic. An efficient mechanism of automatic resource discovery is needed in order to discover new producers of workflow monitoring data fast. However, currently used Grid information systems are not s

  6. Electrochemical oxidation and cleavage of peptides analyzed with on-line mass spectrometric detection

    NARCIS (Netherlands)

    Permentier, H.P.; Jurva, U; Barroso, B.; Bruins, A.P.

    2003-01-01

    An on-line electrochernistry/electrospray mass spectrometry system (EC/MS) is described that allows fast analysis of the oxidation products of peptides. A range of peptides was oxidized in an electrochemical cell by application of a potential ramp from 0 to 1.5 V during passage of the sample. Electr

  7. VibrioBase: A MALDI-TOF MS database for fast identification of Vibrio spp. that are potentially pathogenic in humans.

    Science.gov (United States)

    Erler, René; Wichels, Antje; Heinemeyer, Ernst-August; Hauk, Gerhard; Hippelein, Martin; Reyes, Nadja Torres; Gerdts, Gunnar

    2015-02-01

    Mesophilic marine bacteria of the family Vibrionaceae, specifically V. cholerae, V. parahaemolyticus and V. vulnificus, are considered to cause severe illness in humans. Due to climate-change-driven temperature increases, higher Vibrio abundances and infections are predicted for Northern Europe, which in turn necessitates environmental surveillance programs to evaluate this risk. We propose that whole-cell matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) profiling is a promising tool for the fast and reliable species classification of environmental isolates. Because the reference database does not contain sufficient Vibrio spectra we generated the VibrioBase database in this study. Mass spectrometric data were generated from 997 largely environmental strains and filed in this new database. MALDI-TOF MS clusters were assigned based on the species classification obtained by analysis of partial rpoB (RNA polymerase beta-subunit) sequences. The affiliation of strains to species-specific clusters was consistent in 97% of all cases using both approaches, and the extended VibrioBase generated more specific species identifications with higher matching scores compared to the commercially available database. Therefore, we have made the VibrioBase database freely accessible, which paves the way for detailed risk assessment studies of potentially pathogenic Vibrio spp. from marine environments.

  8. On-Line Core Thermal-Hydraulic Model Improvement

    Energy Technology Data Exchange (ETDEWEB)

    In, Wang Kee; Chun, Tae Hyun; Oh, Dong Seok; Shin, Chang Hwan; Hwang, Dae Hyun; Seo, Kyung Won

    2007-02-15

    The objective of this project is to implement a fast-running 4-channel based code CETOP-D in an advanced reactor core protection calculator system(RCOPS). The part required for the on-line calculation of DNBR were extracted from the source of the CETOP-D code based on analysis of the CETOP-D code. The CETOP-D code was revised to maintain the input and output variables which are the same as in CPC DNBR module. Since the DNBR module performs a complex calculation, it is divided into sub-modules per major calculation step. The functional design requirements for the DNBR module is documented and the values of the database(DB) constants were decided. This project also developed a Fortran module(BEST) of the RCOPS Fortran Simulator and a computer code RCOPS-SDNBR to independently calculate DNBR. A test was also conducted to verify the functional design and DB of thermal-hydraulic model which is necessary to calculate the DNBR on-line in RCOPS. The DNBR margin is expected to increase by 2%-3% once the CETOP-D code is used to calculate the RCOPS DNBR. It should be noted that the final DNBR margin improvement could be determined in the future based on overall uncertainty analysis of the RCOPS.

  9. On-line parameter, state-of-charge and aging estimation of Li-ion batteries

    NARCIS (Netherlands)

    Rosca, B.; Kessels, J.T.B.A.; Bergveld, H.J.; Bosch, P.P.J. van den

    2012-01-01

    This paper presents an on-line model identification method for Li-ion battery parameters that combines high accuracy and low computational complexity. Experimental results show that modeling errors are smaller than 1% throughout the feasible operating range. The identified model is used in a state

  10. Educational On-Line Gaming Propensity

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana; Kirchner, Kathrin

    2014-01-01

    Educational on-line games are promising for new generations of students who are grown up digital. Th e new generations of students are technology savvy and spend lots of time on the web and on social networks. Based on an exploratory study, this article investigates the factors that infl uence...... students’ willingness to participate in serious games for teaching/learning. Th is study investigates the relationship between students’ behavior on Facebook, Facebook games, and their attitude toward educational on-line games. Th e results of the study reveal that the early adopters of educational games...... are likely to be students, who are young, have only a few Facebook connections, who currently play Facebook game(s). Furthermore, the study emphasizes that there may be differences between students coming from various countries....

  11. New Trends in on-line Marketing

    OpenAIRE

    Palkovič, Lukáš

    2011-01-01

    This bachelor thesis deals with new trend of internet marketing, it focuses especially on viral marketing. The theoretical part charasterizes the process of viral campaigns, furthermore deals with the components and aspects of on-line environment. Another separated chapter presents social networks, their place in viral marketing and at last but not least the viral video making process. The practical part contains different analyses of specific viral campaigns. The next and equally the last pa...

  12. A Fingerprint Minutiae Matching Method Based on Line Segment Vector

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Minutiae-based fingerprint matching is the most commonly used in an automatic fingerprint identification system. In this paper, we propose a minutia matching method based on line segment vector. This method uses all the detected minutiae (the ridge ending and the ridge bifurcation) in a fingerprint image to create a set of new vectors (line segment vector). Using these vectors, we can determine a truer reference point more efficiently. In addition, this new minutiae vector can also increase the accuracy of the minutiae matching. By experiment on the public domain collections of fingerprint images fvc2004 DB3 set A and DB4 set A, the result shows that our algorithm can obtain an improved verification performance.

  13. Development and testing of a fast digital electronic system for ion identification and spectroscopy; Etude et realisation d'une chaine d'instrumentation numerique rapide pour l'identification des ions

    Energy Technology Data Exchange (ETDEWEB)

    Legou, Th

    2002-02-01

    This report deals with a fast digital electronic system developed for ion identification and spectroscopy. The system, called IRIS, has been conceived for the super heavy element research program: FUSION. In order to observe a super heavy element, the energy of the compound nucleus implanted in a silicon detector must be measured, and the alpha decay also registered. The associated electronics must therefore handle a very wide range of energies and also exhibit a small recovery time after the implantation of the compound nucleus. IRIS is connected to the output of a charge preamplifier. It digitizes the signal and then executes two digital signal processes: the first to detect the particle, and the second to determine the energy deposited in the silicon detector. The use of programmed processing allows for the adjustment of the digital processing parameters, as well as a choice of other digital signal processing procedures, depending the application. After having explained why a conventional electronic system cannot be used for the detection of super-heavy ions, IRIS' structure is detailed and a number of digital signal processing procedures are studied and tested. (author)

  14. Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing

    Science.gov (United States)

    Poleksic, Aleksandar; Yao, Yuan; Tong, Hanghang; Meng, Patrick; Xie, Lei

    2016-01-01

    Target-based screening is one of the major approaches in drug discovery. Besides the intended target, unexpected drug off-target interactions often occur, and many of them have not been recognized and characterized. The off-target interactions can be responsible for either therapeutic or side effects. Thus, identifying the genome-wide off-targets of lead compounds or existing drugs will be critical for designing effective and safe drugs, and providing new opportunities for drug repurposing. Although many computational methods have been developed to predict drug-target interactions, they are either less accurate than the one that we are proposing here or computationally too intensive, thereby limiting their capability for large-scale off-target identification. In addition, the performances of most machine learning based algorithms have been mainly evaluated to predict off-target interactions in the same gene family for hundreds of chemicals. It is not clear how these algorithms perform in terms of detecting off-targets across gene families on a proteome scale. Here, we are presenting a fast and accurate off-target prediction method, REMAP, which is based on a dual regularized one-class collaborative filtering algorithm, to explore continuous chemical space, protein space, and their interactome on a large scale. When tested in a reliable, extensive, and cross-gene family benchmark, REMAP outperforms the state-of-the-art methods. Furthermore, REMAP is highly scalable. It can screen a dataset of 200 thousands chemicals against 20 thousands proteins within 2 hours. Using the reconstructed genome-wide target profile as the fingerprint of a chemical compound, we predicted that seven FDA-approved drugs can be repurposed as novel anti-cancer therapies. The anti-cancer activity of six of them is supported by experimental evidences. Thus, REMAP is a valuable addition to the existing in silico toolbox for drug target identification, drug repurposing, phenotypic screening, and

  15. Remote Spectroscopic Identification of Bloodstains

    NARCIS (Netherlands)

    R.H. Bremmer; G. Edelman; T. Dijn Vegter; T. Bijvoets; M.C.G. Aalders

    2011-01-01

    Blood detection and identification at crime scenes are crucial for harvesting forensic evidence. Unfortunately, most tests for the identification of blood are destructive and time consuming. We present a fast and nondestructive identification test for blood, using noncontact reflectance spectroscopy

  16. Total on-line purchasing system (TOPS)

    Energy Technology Data Exchange (ETDEWEB)

    Collins, N.

    1995-11-01

    The Information Management Division (IMD) at LLNL is developing a new purchasing system for the Procurement Department. The first major development of this new system is called, {open_quotes}Total On-Line Purchasing System{close_quotes} (TOPS). TOPS will help speed up the requisitioning process by having requisitions electronically entered by requesters and electronically sent to buyers to be put on Purchase Orders. The new purchasing system will use Electronic Commerce (EC)/Electronic Data Interchange (EDI), to help increase transaction flows for shipping notices, RFQs, Quotes, Purchase Orders, and Invoices. ANSI X.12 is the EDI standard that this new EC will use.

  17. ON-LINE STATE PREDICTION OF ENGINES BASED ON FLAT NEURAL NETWORK

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A flat neural network is designed for the on-line state prediction of engine. To reduce the computational cost of weight matrix, a fast recursive algorithm is derived according to the pseudoinverse formula of a partition matrix. Furthermore, the forgetting factor approach is introduced to improve predictive accuracy and robustness of the model. The experiment results indicate that the improved neural network is of good accuracy and strong robustness in prediction, and can apply for the on-line prediction of nonlinear multi input multi output systems like vehicle engines.

  18. On-line and Mobil Learning Activities

    Science.gov (United States)

    Ackerman, S. A.; Whittaker, T. M.; Jasmin, T.; Mooney, M. E.

    2012-12-01

    Introductory college-level science courses for non-majors are critical gateways to imparting not only discipline-specific information, but also the basics of the scientific method and how science influences society. They are also indispensable for student success to degree. On-line, web-based homework (whether on computers or mobile devices) is a rapidly growing use of the Internet and is becoming a major component of instruction in science, replacing delayed feedback from a few major exams. Web delivery and grading of traditional textbook-type questions is equally effective as having students write them out for hand grading, as measured by student performance on conceptual and problem solving exams. During this presentation we will demonstrate some of the interactive on-line activities used to teach concepts and how scientists approach problem solving, and how these activities have impacted student learning. Evaluation of the activities, including formative and summative, will be discussed and provide evidence that these interactive activities significantly enhance understanding of introductory meteorological concepts in a college-level science course. More advanced interactive activities are also used in our courses for department majors, some of these will be discussed and demonstrated. Bring your mobile devices to play along! Here is an example on teaching contouring: http://profhorn.aos.wisc.edu/wxwise/contour/index.html

  19. On-line alkali detector based on surface ionization

    Energy Technology Data Exchange (ETDEWEB)

    Olsson, J.G.; Loenn, B.; Jaeglid, B.; Engvall, K.; Pettersson, J.B.C. [Chalmers University of Technology, Goeteborg (Sweden). Dept. of Physical Chemistry GU

    1998-12-31

    This project adapts a new on-line alkali measurement technique to coal and biomass combustion and gasification. Alkali metal atoms are known to easily ionize in contact with hot metal surfaces, and the instrument is based on this principle called surface ionization (SI). The primary parts of the detector are a platinum filament and an ion collector. The platinum filament is supported between two electrodes and heated to the temperature for alkali vaporization in ionic form. The ion collector is situated close to the filament. The measured current is proportional to the arrival rate of alkali atoms onto the filament. Laboratory tests were performed on detector sensitivity, detection limit, and time response. Similar sensitivity to both sodium and potassium regardless of molecular form was found. The time response of the detector is determined to be approximately 1 ms enabling it to monitor fast concentration changes in flue gas. Particles with a size below 5 nm melt completely on the hot platinum surface and give similar signals. For larger particles, the ionization efficiency is not 100% and depends on the type of salt. This problem can be overcome with an alternative filament configuration. The detector function was tested in a laboratory high pressure furnace using different fuel samples, atmospheres, and pressures. Alkali release from coal in general is lower than for biomass samples, rate constants and activation energies for alkali release were determined. Measurements were carried out in a biomass pyrolysis apparatus and a gasification pilot plant. The detector function was not influenced by a high concentration of hydrocarbons in the gas phase, and the measurements confirmed detector function in a hostile environment. The detector performed well in laboratory tests, and is a strong candidate for further development into a standard on-line monitor of alkali species in hot flue gas. 10 refs., 16 figs.

  20. Aprender a innovar: una experiencia on line

    Directory of Open Access Journals (Sweden)

    Joaquín MORENO MARCHAL

    2014-11-01

    Full Text Available La creatividad y la innovación se han convertido en recursos clave en la denominada sociedad del conocimiento, que bien podría ser también llamada sociedad de la innovación. Pero innovar es una actividad compleja, que integra la aplicación de múltiples capacidades, el pensamiento divergente y convergente, la gestión de equipos humanos, la comunicación. Ahora bien, a innovar se puede, y se debe, aprender. Aprender a innovar es un reto y también una obligación para el conjunto del sistema educativo en todos sus niveles. Partiendo de estas consideraciones este trabajo expone una experiencia de aprendizaje de la creatividad y de la innovación a través de un curso totalmente on line basado en la plataforma MOODLE, en el marco del Programa de Formación Permanente de la Universidad de Cádiz. Se presenta un modelo del proceso de innovación, denominado CREALAB, de elaboración propia. Este modelo se ha utilizado como base del proceso de aprendizaje de la creatividad y de la innovación y en el diseño del curso, está organizado en torno a actividades y tiene un carácter iterativo y realimentado. Se presentan además el conjunto del diseño metodológico y los resultados obtenidos en las dos ediciones celebradas hasta el momento. El diseño del curso totalmente on line y los resultados alcanzados permiten estimar un alto potencial de aplicación, tanto a nivel personal como a nivel organizacional.

  1. On-line chemical composition analyzer development

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, M.J.; Garrison, A.A.; Muly, E.C.; Moore, C.F.

    1992-02-01

    The energy consumed in distillation processes in the United States represents nearly three percent of the total national energy consumption. If effective control of distillation columns can be accomplished, it has been estimated that it would result in a reduction in the national energy consumption of 0.3%. Real-time control based on mixture composition could achieve these savings. However, the major distillation processes represent diverse applications and at present there does not exist a proven on-line chemical composition sensor technology which can be used to control these diverse processes in real-time. This report presents a summary of the findings of the second phase of a three phase effort undertaken to develop an on-line real-time measurement and control system utilizing Raman spectroscopy. A prototype instrument system has been constructed utilizing a Perkin Elmer 1700 Spectrometer, a diode pumped YAG laser, two three axis positioning systems, a process sample cell land a personal computer. This system has been successfully tested using industrially supplied process samples to establish its performance. Also, continued application development was undertaken during this Phase of the program using both the spontaneous Raman and Surface-enhanced Raman modes of operation. The study was performed for the US Department of Energy, Office of Industrial Technologies, whose mission is to conduct cost-shared R D for new high-risk, high-payoff industrial energy conservation technologies. Although this document contains references to individual manufacturers and their products, the opinions expressed on the products reported do not necessarily reflect the position of the Department of Energy.

  2. Identification of differentially expressed genes and pathways for intramuscular fat deposition in pectoralis major tissues of fast-and slow-growing chickens

    Directory of Open Access Journals (Sweden)

    Cui Huan-Xian

    2012-05-01

    Full Text Available Abstract Background Intramuscular fat (IMF is one of the important factors influencing meat quality, however, for chickens, the molecular regulatory mechanisms underlying this trait have not yet been determined. In this study, a systematic identification of candidate genes and new pathways related to IMF deposition in chicken breast tissue has been made using gene expression profiles of two distinct breeds: Beijing-you (BJY, a slow-growing Chinese breed possessing high meat quality and Arbor Acres (AA, a commercial fast-growing broiler line. Results Agilent cDNA microarray analyses were conducted to determine gene expression profiles of breast muscle sampled at different developmental stages of BJY and AA chickens. Relative to d 1 when there is no detectable IMF, breast muscle at d 21, d 42, d 90 and d 120 (only for BJY contained 1310 differentially expressed genes (DEGs in BJY and 1080 DEGs in AA. Of these, 34–70 DEGs related to lipid metabolism or muscle development processes were examined further in each breed based on Gene Ontology (GO analysis. The expression of several DEGs was correlated, positively or negatively, with the changing patterns of lipid content or breast weight across the ages sampled, indicating that those genes may play key roles in these developmental processes. In addition, based on KEGG pathway analysis of DEGs in both BJY and AA chickens, it was found that in addition to pathways affecting lipid metabolism (pathways for MAPK & PPAR signaling, cell junction-related pathways (tight junction, ECM-receptor interaction, focal adhesion, regulation of actin cytoskeleton, which play a prominent role in maintaining the integrity of tissues, could contribute to the IMF deposition. Conclusion The results of this study identified potential candidate genes associated with chicken IMF deposition and imply that IMF deposition in chicken breast muscle is regulated and mediated not only by genes and pathways related to lipid

  3. Fast Identification of Near-Trench Earthquakes Along the Mexican Subduction Zone Based on Characteristics of Ground Motion in Mexico City

    Science.gov (United States)

    Perez-Campos, X.; Singh, S. K.; Arroyo, D.; Rodríguez, Q.; Iglesias, A.

    2015-12-01

    The disastrous 1985 Michoacan earthquake gave rise to a seismic alert system for Mexico City which became operational in 1991. Initially limited to earthquakes along the Guerrero coast, the system now has a much wider coverage. Also, the 2004 Sumatra earthquake exposed the need for a tsunami early warning along the Mexican subduction zone. A fast identification of near-trench earthquakes along this zone may be useful in issuing a reliable early tsunami alert. The confusion caused by low PGA for the magnitude of an earthquake, leading to "missed" seismic alert, would be averted if its near-trench origin can be quickly established. It may also help reveal the spatial extent and degree of seismic coupling on the near-trench portion of the plate interface. This would lead to a better understanding of tsunami potential and seismic hazard along the Mexican subduction zone. We explore three methods for quick detection of near-trench earthquakes, testing them on recordings of 65 earthquakes at station CU in Mexico City (4.8 ≤Mw≤8.0; 270≤R≤615 km). The first method is based on the ratio of total to high-frequency energy, ER (Shapiro et al., 1998). The second method is based on parameter Sa*(6) which is the pseudo-acceleration response spectrum with 5% damping, Sa, at 6 s normalized by the PGA. The third parameter is the PGA residual, RESN, at CU, with respect to a newly-derived ground motion prediction equation at CU for coastal shallow-dipping thrust earthquakes following a bayesian approach. Since the near-trench earthquakes are relatively deficient in high-frequency radiation, we expect ER and Sa*(6) to be relatively large and RESN to be negative for such events. Tests on CU recordings show that if ER ≥ 100 and/or Sa*(6) ≥ 0.70, then the earthquake is near trench; for these events RESN ≤ 0. Such an event has greater tsunami potential. Few misidentifications and missed events are most probably a consequence of poor location, although unusual depth and source

  4. Review of Worcestershire On-line Fabric Type Series website

    Directory of Open Access Journals (Sweden)

    Beverley Nenk

    2003-06-01

    Full Text Available The study of archaeological ceramics is advanced through the creation and development of regional and national pottery type-series, which contain samples of each type of pottery identified from a particular area or region. Pottery researchers working in any period, from prehistoric to post-medieval, require access to such type-series, and to their associated data, in order to be able to advance the identification of all types of pottery, not only those types produced in the local area, but those produced in surrounding regions, as well as those imported from abroad. The publication of such type-series, as well as their accessibility to researchers, is essential if the information they contain is to be disseminated. The development of the Worcestershire On-Line Fabric Type Series is the first stage in a remarkable project designed to make the complete fabric and form type series for Worcestershire ceramics accessible on the internet. As part of the Historic Environment Record for Worcestershire, formerly the Sites and Monuments Record, it is designed to improve access to finds and environmental data, with the aim of encouraging and facilitating research. Funded by Worcestershire County Council as part of its commitment to e-government, it is being developed by Worcestershire County Council Archaeology Service with OxfordArchDigital. It is one of a proposed series of on-line specialist resources (to include, for example, clay pipes, environmental archaeology, flint tools, historic buildings, which are also designed to stand alone as research tools. The ceramics website is the first part of Pottery in Perspective, a web-based project to provide information on the pottery used and made in Worcestershire from prehistory to c. 1900AD.

  5. Active control of time-varying broadband noise using online system identification with parallel fast-array recursive least squares filters

    NARCIS (Netherlands)

    Berkhoff, Arthur P.; Meijer, H.J.; van Ophem, S.; Sas, P

    2016-01-01

    For broadband active noise control applications with rapidly changing transfer paths, it is desirable to find algorithms with rapid convergence, fast tracking performance, and low computational cost. Recently, a numerically stable algorithm has been presented: a convex mixing fast-array RLS filter.

  6. Influence of visualization on consumption during on-line shopping

    OpenAIRE

    Hictaler, Urška

    2013-01-01

    This diploma work studies the influence of visualization on consumption during on-line shopping. The first part of the thesis starts with key areas of visualization, consumption and on-line shopping. Visualization, areas of use, human perception and ways of product presentation in on-line shops are defined discussed first. Next, consumption, consumers and factors that influence their decisions and satisfaction are defined. The last topic in the first part of the thesis discusses on-line shopp...

  7. On-Line Learning: One Way to Bring People Together

    Science.gov (United States)

    Goff-Kfouri, Carol Ann

    2006-01-01

    The purpose of this study was to demonstrate the benefits of on-line learning for adult learners and to further demystify three common misconceptions concerning on-line learning: students certainly do receive support from their on-line professors, the professor is pro-active rather than passive, and students may be more motivated to learn than in…

  8. A Distributed System for Learning Programming On-Line

    Science.gov (United States)

    Verdu, Elena; Regueras, Luisa M.; Verdu, Maria J.; Leal, Jose P.; de Castro, Juan P.; Queiros, Ricardo

    2012-01-01

    Several Web-based on-line judges or on-line programming trainers have been developed in order to allow students to train their programming skills. However, their pedagogical functionalities in the learning of programming have not been clearly defined. EduJudge is a project which aims to integrate the "UVA On-line Judge", an existing…

  9. SOL: INNOVACIÓN ON-LINE

    Directory of Open Access Journals (Sweden)

    Rubén Faúndez

    2007-11-01

    Full Text Available Las aplicaciones de simulación tienden a ser cada vez más cercanas a usuarios e industrias. Sin embargo, muchas de ellas no poseen ni la capacidad ni el conocimiento como para desarrollar internamente sus modelos de simulación. Por este motivo, y como una forma de apoyar la toma de decisiones basándose en modelos de simulación, se presenta la plataforma SOL (Simulación On Line. La metodología completa de trabajo, así como la interacción entre SOL, Empresa y Asesor, son presentadas. Su base de datos, los niveles de usuarios, sus funcionalidades, y la creación automatizada de información grafica y visual, también son explicadas. En el caso de aplicación, el uso de SOL para apoyar la toma de decisiones en una operación de movimiento de material, permite a los tomadores de decisión acceder a análisis robustos basados en información extraída de los modelos de simulación. SOL, al almacenar información, funcionar vía web, generar análisis automatizados y crear visualizaciones, permite cumplir con las expectativas de los usuarios respecto a una solución integral en simulación.

  10. On-line range images registration with GPGPU

    Science.gov (United States)

    Będkowski, J.; Naruniec, J.

    2013-03-01

    This paper concerns implementation of algorithms in the two important aspects of modern 3D data processing: data registration and segmentation. Solution proposed for the first topic is based on the 3D space decomposition, while the latter on image processing and local neighbourhood search. Data processing is implemented by using NVIDIA compute unified device architecture (NIVIDIA CUDA) parallel computation. The result of the segmentation is a coloured map where different colours correspond to different objects, such as walls, floor and stairs. The research is related to the problem of collecting 3D data with a RGB-D camera mounted on a rotated head, to be used in mobile robot applications. Performance of the data registration algorithm is aimed for on-line processing. The iterative closest point (ICP) approach is chosen as a registration method. Computations are based on the parallel fast nearest neighbour search. This procedure decomposes 3D space into cubic buckets and, therefore, the time of the matching is deterministic. First technique of the data segmentation uses accele-rometers integrated with a RGB-D sensor to obtain rotation compensation and image processing method for defining pre-requisites of the known categories. The second technique uses the adapted nearest neighbour search procedure for obtaining normal vectors for each range point.

  11. Fast Analysis of Vitamin A and E in Animal Derived Foods by On-Line Solid Phase Extraction Coupled with High Performance Liquid Chromatography%在线固相萃取-高效液相色谱联用测定动物源食品中的维生素A、E

    Institute of Scientific and Technical Information of China (English)

    谢云峰; 王浩; 刘佟; 任丹丹; 杨永坛

    2014-01-01

    采用固相萃取与双梯度高效液相色谱联用技术,建立了一种在线固相萃取-高效液相色谱同时测定动物源食品中维生素A、E的分析方法。样品于80℃下皂化反应30 min,经离心沉淀后引入一维C8固相萃取柱,采用60%( V/V)甲醇溶液对目标物进行在线富集净化,然后通过阀切换将其转移至二维液相分析系统进行分离检测。考察了萃取填料、上样溶剂及洗脱条件对猪肝、鸡蛋和配方乳粉的维生素A、E富集和基质净化效果。结果表明,在优化条件下,方法线性范围为0.02~20 mg/L,线性相关系数R2≥0.9998,对维生素A、E的检出限(S/N=3)为3.0~30.0μg/L,实际样品加标回收率为87.3%~115.0%,相对标准偏差(RSD)为1.8%~4.6%。本方法操作简便,灵敏度高,可用于动物源食品中维生素A、E的快速测定。%An automated analytical method for simultaneous determination of vitamin A and E in livers, fortified infant formulae and eggs has been developed based on on-line solid phase extraction (SPE) coupled with a dual gradient high performance liquid chromatography system with column-switching. Firstly, food samples were centrifuged after saponified in mixture solution of anhydrous alcohol, potassium hydroxide and ascorbic acid at 80 ℃ for 30 min. Secondly, the saponified sample was loaded and washed on the first dimension extraction column using methanol-water (60∶40, V/V). Afterwards, the targeted analytes were trapped and enriched on the SPE column. Finally, the trapped analytes were transferred to the second dimension analysis column by valve-switching technique for the following separation and determination. Several key factors such as the type of SPE columns, elution buffer as well as pH of washing solution were optimized. The results showed that the calibration curves of vitamin A and E were linear in the range of 0 . 02-20 mg/L with correlation coefficient (R2) more than 0. 9998. In addition, the limits of detection

  12. On-line parameter and delay estimation of continuous-time dynamic systems

    Directory of Open Access Journals (Sweden)

    Kozłowski Janusz

    2015-06-01

    Full Text Available The problem of on-line identification of non-stationary delay systems is considered. The dynamics of supervised industrial processes are usually modeled by ordinary differential equations. Discrete-time mechanizations of continuous-time process models are implemented with the use of dedicated finite-horizon integrating filters. Least-squares and instrumental variable procedures mechanized in recursive forms are applied for simultaneous identification of input delay and spectral parameters of the system models. The performance of the proposed estimation algorithms is verified in an illustrative numerical simulation study.

  13. Identification of differentially expressed genes and pathways for intramuscular fat deposition in pectoralis major tissues of fast-and slow-growing chickens

    National Research Council Canada - National Science Library

    Cui, Huan-Xian; Liu, Ran-Ran; Zhao, Gui-Ping; Zheng, Mai-Qing; Chen, Ji-Lan; Wen, Jie

    2012-01-01

    .... In this study, a systematic identification of candidate genes and new pathways related to IMF deposition in chicken breast tissue has been made using gene expression profiles of two distinct breeds: Beijing-you (BJY...

  14. Subspace Identification

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2002-01-01

    Subspace identification algorithms are user friendly, numerical fast and stable and they provide a good consistent estimate of the deterministic part of a system. The weak point is the stochastic part. The uncertainty on this part is discussed below and methods to reduce it is derived....

  15. Subspace Identification

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2001-01-01

    Subspace identification algorithms are user friendly, numerical fast and stable and they provide a good consistent estimate of the deterministic part of a system. The weak point is the stochastic part. The uncertainty on this part is discussed below and methods to reduce it is derived....

  16. LC-HR-MS/MS standard urine screening approach: Pros and cons of automated on-line extraction by turbulent flow chromatography versus dilute-and-shoot and comparison with established urine precipitation.

    Science.gov (United States)

    Helfer, Andreas G; Michely, Julian A; Weber, Armin A; Meyer, Markus R; Maurer, Hans H

    2017-02-01

    Comprehensive urine screening for drugs and metabolites by LC-HR-MS/MS using Orbitrap technology has been described with precipitation as simple workup. In order to fasten, automate, and/or simplify the workup, on-line extraction by turbulent flow chromatography and a dilute-and-shoot approach were developed and compared. After chromatographic separation within 10min, the Q-Exactive mass spectrometer was run in full scan mode with positive/negative switching and subsequent data dependent acquisition mode. The workup approaches were validated concerning selectivity, recovery, matrix effects, process efficiency, and limits of identification and detection for typical drug representatives and metabolites. The total workup time for on-line extraction was 6min, for the dilution approach 3min. For comparison, the established urine precipitation and evaporation lasted 10min. The validation results were acceptable. The limits for on-line extraction were comparable with those described for precipitation, but lower than for dilution. Thanks to the high sensitivity of the LC-HR-MS/MS system, all three workup approaches were sufficient for comprehensive urine screening and allowed fast, reliable, and reproducible detection of cardiovascular drugs, drugs of abuse, and other CNS acting drugs after common doses.

  17. An automated on-line multidimensional HPLC system for protein and peptide mapping with integrated sample preparation

    NARCIS (Netherlands)

    Wagner, K.; Miliotis, T.; Marko-Varga, G; Bischoff, Rainer; Unger, K.K.

    2002-01-01

    A comprehensive on-line two-dimensional 2D-HPLC system with integrated sample preparation was developed for the analysis of proteins and peptides with a molecular weight below 20 kDa. The system setup provided fast separations and high resolving power and is considered to be a complementary techniqu

  18. Properties of on-line social systems

    Science.gov (United States)

    Grabowski, A.; Kruszewska, N.; Kosiński, R. A.

    2008-11-01

    We study properties of five different social systems: (i) internet society of friends consisting of over 106 people, (ii) social network consisting of 3 × 104 individuals, who interact in a large virtual world of Massive Multiplayer Online Role Playing Games (MMORPGs), (iii) over 106 users of music community website, (iv) over 5 × 106 users of gamers community server and (v) over 0.25 × 106 users of books admirer website. Individuals included in large social network form an Internet community and organize themselves in groups of different sizes. The destiny of those systems, as well as the method of creating of new connections, are different, however we found that the properties of these networks are very similar. We have found that the network components size distribution follow the power-law scaling form. In all five systems we have found interesting scaling laws concerning human dynamics. Our research has shown how long people are interested in a single task, how much time they devote to it and how fast they are making friends. It is surprising that the time evolution of an individual connectivity is very similar in each system.

  19. Robust on-line monitoring of biogas processes; Robusta maettekniker on-line foer optimerad biogasproduktion

    Energy Technology Data Exchange (ETDEWEB)

    Nordberg, Aake; Hansson, Mikael; Kanerot, Mija; Krozer, Anatol; Loefving, Bjoern; Sahlin, Eskil

    2010-03-15

    Although demand for biomethane in Sweden is higher than ever, many Swedish codigestion plants are presently operated below their designed capacity. Efforts must be taken to increase the loading rate and guarantee stable operation and high availability of the plants. There are currently no commercial systems for on-line monitoring, and due to the characteristics of the material, including corrosion and tearing, robust applications have to be developed. The objective of this project was to identify and study different monitoring technologies with potential for on-line monitoring of both substrate mixtures and anaerobic digester content. Based on the prerequisites and demands at Boraas Energi och Miljoe AB's (BEMAB, the municipal energy and waste utility in the city of Boraas, Sweden) biogas plant, the extent of the problems, measurement variables and possible ways of managing these issues have been identified and prioritized. The substrate mixtures in question have a high viscosity and are inhomogeneous with variation in composition, which calls for further homogenization, dilution and filtration to achieve high precision in the necessary analyses. Studies of using different mixers and mills showed that the particle size (800 mum) needed for on-line COD measurement could not be achieved. The problem of homogenization can be avoided if indirect measurement methods are used. Laboratory tests with NIR (near-infra red spectroscopy) showed that VS can be predicted (R2=0,78) in the interval of 2-9% VS. Furthermore, impedance can give a measurement of soluble components. However, impedance is not sensitive enough to give a good measurement of total TS. Microwave technology was installed at the production plant and showed a faster response to changes in TS than the existing TS-sensor. However, due to technical problems, the evaluation only could be done during a limited period of ten days. BEMAB will continue the measurements and evaluation of the instrument. The

  20. DOE-EPRI On-Line Monitoring Implementation Guidelines

    Energy Technology Data Exchange (ETDEWEB)

    E. Davis, R. Bickford

    2003-01-02

    Industry and EPRI experience at several plants has shown on-line monitoring to be very effective in identifying out-of-calibration instrument channels or indications of equipment-degradation problems. The EPRI implementation project for on-line monitoring has demonstrated the feasability of on-line monitoring at several participating nuclear plants. The results have been very enouraging, and substantial progress is anticipated in the coming years.

  1. On-line MSPD-SPE-HPLC/FLD analysis of polycyclic aromatic hydrocarbons in bovine tissues.

    Science.gov (United States)

    Gutiérrez-Valencia, Tania M; García de Llasera, Martha P

    2017-05-15

    A fast method was optimized and validated for simultaneous trace determination of four polycyclic aromatic hydrocarbons: benzo[a]anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene and benzo[a]pyrene in bovine tissues. The determination was performed by matrix solid-phase dispersion (MSPD) coupled on-line to solid phase extraction (SPE) and high performance liquid chromatography (HPLC) with fluorescence detection (FLD). The sample was dispersed on C18 silica sorbent and then the on-line MSPD-SPE-HPLC/FLD method was applied. Several parameters were optimized: cleaning and elution sequences applied to the MSPD cartridge, the flow rate and dilution of extract used for SPE loading. The on-line method was validated over a concentration range of 0.1-0.6ngg(-1) obtaining good linearity (r⩾0.998) and precision (RSD)⩽10%. Recovery ranged from 96 to 99% and the limits of detection were 0.012ngg(-1). This methodology was applied to liver samples from unhealthy animals. The results demonstrate that MSDP-SPE-HPLC/FLD method provides reliable, sensitive, accurate and fast data to the food control.

  2. Identification and further differentiation of subendocardial and transmural myocardial infarction by fast strain-encoded (SENC) magnetic resonance imaging at 3.0 tesla

    Energy Technology Data Exchange (ETDEWEB)

    Oyama-Manabe, Noriko; Sugimori, Hiroyuki; Kamishima, Tamotsu; Tha, Khin Khin; Terae, Satoshi; Shirato, Hiroki [Hokkaido University Hospital, Department of Diagnostic and Interventional Radiology, Sapporo (Japan); Ishimori, Naoki; Tsutsui, Hiroyuki [Hokkaido University Graduate School of Medicine, Department of Cardiovascular Medicine, Sapporo (Japan); Van Cauteren, Marc; Okuaki, Tomoyuki [Philips Healthcase, MR Clinical Science, Tokyo (Japan); Kudo, Kohsuke [Iwate Medical University, Advanced Medical Research Center, Morioka (Japan); Manabe, Osamu [Hokkaido University Hospital, Department of Nuclear Medicine, Sapporo (Japan); Ito, Yoichi M. [Hokkaido University Graduate School of Medicine, Hokkaido Organization for Translational Research, Sapporo (Japan)

    2011-11-15

    To investigate whether subendocardial and transmural myocardial infarction can be identified and differentiated using the peak circumferential and longitudinal strains measured by fast strain-encoded (SENC). Nineteen patients with ischemic heart diseases underwent imaging with fast SENC and late gadolinium enhancement (LGE) MRI at 3 T. Fast SENC measurements were performed in three short-axis slices (basal, mid-ventricular and apical levels) and one long-axis view (four-chamber) to assess peak longitudinal and circumferential systolic strains. All patients showed myocardial infarction with an average of 7 positive LGE segments. A total of 304 segments for longitudinal strains (LS) and 114 segments for circumferential strains (CS) could be analysed. Positive LGE segments showed lower peak CS and LS compared with the no LGE segments (P < 0.0001 for both). Segments with subendocardial infarction showed reduced CS and LS compared with the no LGE segments (P < 0.0001 for both). There was a significant difference in CS between subendocardial and transmural infarct segments (P = 0.03), but no significant difference in LS between them (P = 0.64). Fast SENC can identify old myocardial infarction and differentiate subendocardial from transmural infarction. (orig.)

  3. Poss On-line (Personalisation of Self-Service Solutions across On-line platforms)

    DEFF Research Database (Denmark)

    Nielsen, Janni; Nielsen, Lene; Jespersen, Mikkel

    2005-01-01

    The project on Personalisation of Self-service Solutions across On-line Platforms (POSS ON-LINE) focuses on users, clients, and self-service solutions. It is based on the understanding that clients and users are different and have different goals, and that self-service takes place in different co...... at the process of development. However, we lack methods to predict user behaviour without having to deal with huge amounts of data and data from both quantitative data as well as life world observations are required....... the client and the user. The system gathers data about the user, which enables the client to push information to the user. Personalisation enables graphic user interface design that is personalised and relevant to the individual user and invites the user to get access to information with less strain....... Personalisation of self-service solutions is promising and IT companies are experiencing an increase in the clients' demands. At the same time the development of solutions moves within a shorter and shorter time span. Hence the process of innovations is paced and there is an increasing need of new ways of looking...

  4. COMUNICAREA ON-LINE PRIN INTERMEDIUL BLOG-URILOR (ON-LINE COMMUNICATION THROUGH BLOGS)

    OpenAIRE

    Cristian Morozan

    2006-01-01

    In today’s society blog-writing represents an activity through which people make public their observations, reflections, reactions and dilemmas to the general public or to a smaller category if the information is confidential. The blogs represent a fast and effective way of using IT and the internet, and have a positive effect in PR, journalism, marketing, information management and virtual communities. We would like to emphasize that they are being used extensively especially in public relat...

  5. ON-LINE PREEMPTIVE SCHEDULING ON UNIFORM MACHINES

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yuzhong; WANG Shouyang; Bo Chen; ZHANG Shuxia

    2001-01-01

    We address the problem of preemptively schedule on-line jobs on arbitrary muniformly related machines with the objective of minimizing the schedule length. We provide the first on-line algorithm for this general problem, and show that the algorithm being the speeds of the m machines.

  6. From Off-line to On-line Handwriting Recognition

    NARCIS (Netherlands)

    Lallican, P.; Viard-Gaudin, C.; Knerr, S.

    2004-01-01

    On-line handwriting includes more information on time order of the writing signal and on the dynamics of the writing process than off-line handwriting. Therefore, on-line recognition systems achieve higher recognition rates. This can be concluded from results reported in the literature, and has been

  7. On-Line and Off-Line Assessment of Metacognition

    Science.gov (United States)

    Saraç, Seda; Karakelle, Sema

    2012-01-01

    The study investigates the interrelationships between different on-line and off-line measures for assessing metacognition. The participants were 47 fifth grade elementary students. Metacognition was assessed through two off-line and two on-line measures. The off-line measures consisted of a teacher rating scale and a self-report questionnaire. The…

  8. On-line characterization of a hybridoma cell culture process.

    Science.gov (United States)

    Zhou, W; Hu, W S

    1994-06-20

    The on-line determination of the physiological state of a cell culture process requires reliable on-line measurements of various parameters and calculations of specific rates from these measurements. The cell concentration of a hybridoma culture was estimated on-line by measuring optical density (OD) with a laser turbidity probe. The oxygen uptake rate (OUR) was determined by monitoring dynamically dissolved oxygen concentration profiles and closing oxygen balances in the culture. The base addition for neutralizing lactate produced by cells was also monitored on-line via a balance. Using OD and OUR measurements, the specific growth and specific oxygen consumption rates were determined on-line. By combining predetermined stoichiometric relationships among oxygen and glucose consumption and lactate production, the specific glucose consumption and lactate production rates were also calculated on-line. Using these on-line measurements and calculations, the hybridoma culture process was characterized on-line by identifying the physiological states. They will also facilitate the implementation of nutrient feeding strategies for fed-batch and perfusion cultures. (c) 1994 John Wiley & Sons, Inc.

  9. On-line optimal control of greenhouse crop cultivation.

    NARCIS (Netherlands)

    Straten, van G.

    1996-01-01

    Thus far, optimal control has primarily been investigated for seasonal crop growth optimization. On-line aspects have received much less attention. The decomposition between long term strategies and on-line control, however, is not trivial. Appreciable losses occur when set-points generated by seaso

  10. On-line optimal control of greenhouse crop cultivation.

    NARCIS (Netherlands)

    Straten, van G.

    1996-01-01

    Thus far, optimal control has primarily been investigated for seasonal crop growth optimization. On-line aspects have received much less attention. The decomposition between long term strategies and on-line control, however, is not trivial. Appreciable losses occur when set-points generated by seaso

  11. Algorithms for semi on-line multiprocessor scheduling problems

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In the classical multiprocessor scheduling problems, it is assumed that the problems are considered in off-line or on-line environment. But in practice, problems are often not really off-line or on-line but somehow in between. This means that, with respect to the on-line problem, some further information about the tasks is available, which allows the improvement of the performance of the best possible algorithms. Problems of this class are called semi on-line ones. The authors studied two semi on-line multiprocessor scheduling problems, in which, the total processing time of all tasks is known in advance, or all processing times lie in a given interval. They proposed approximation algorithms for minimizing the makespan and analyzed their performance guarantee. The algorithms improve the known results for 3 or more processor cases in the literature.

  12. Identification of differentially expressed genes and pathways for intramuscular fat deposition in pectoralis major tissues of fast-and slow-growing chickens

    OpenAIRE

    Cui Huan-Xian; Liu Ran-Ran; Zhao Gui-Ping; Zheng Mai-Qing; Chen Ji-Lan; Wen Jie

    2012-01-01

    Abstract Background Intramuscular fat (IMF) is one of the important factors influencing meat quality, however, for chickens, the molecular regulatory mechanisms underlying this trait have not yet been determined. In this study, a systematic identification of candidate genes and new pathways related to IMF deposition in chicken breast tissue has been made using gene expression profiles of two distinct breeds: Beijing-you (BJY), a slow-growing Chinese breed possessing high meat quality and Arbo...

  13. Robust On-Line Fault Diagnosis for Nonlinear Difference-Algebraic Systems Using Least Squares Estimate

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A new robust on-line fault diagnosis method based on least squares estimate for nonlinear difference-algebraic systems (DAS) with uncertainties is proposed. Based on the known nominal model of the DAS, this method firstly constructs an auxiliary system consisting of a difference equation and an algebraic equation, then, based on the relationship between the state deviation and the faults in the difference equation and the relationship between the algebraic variable deviation and the faults in algebraic equation, it identifies the faults on-line through least squares estimate. This method can not only detect, isolate and identify faults for DAS, but also give the upper bound of the error of fault identification. The simulation results indicate that it can give satisfactory diagnostic results for both abrupt and incipient faults.

  14. On-Line Tracking Controller for Brushless DC Motor Drives Using Artificial Neural Networks

    Science.gov (United States)

    Rubaai, Ahmed

    1996-01-01

    A real-time control architecture is developed for time-varying nonlinear brushless dc motors operating in a high performance drives environment. The developed control architecture possesses the capabilities of simultaneous on-line identification and control. The dynamics of the motor are modeled on-line and controlled using an artificial neural network, as the system runs. The control architecture combines the experience and dependability of adaptive tracking systems with potential and promise of the neural computing technology. The sensitivity of real-time controller to parametric changes that occur during training is investigated. Such changes are usually manifested by rapid changes in the load of the brushless motor drives. This sudden change in the external load is simulated for the sigmoidal and sinusoidal reference tracks. The ability of the neuro-controller to maintain reasonable tracking accuracy in the presence of external noise is also verified for a number of desired reference trajectories.

  15. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Fast and Accurate Identification of Cross-Linked Peptides for the structural analysis of large protein complexes and to elucidate interaction networks. Salman Tahir Jimi-Carlo Bukowski-Wills; Morten Rasmussen; Juri RappsilberWellcome Trust Centre for Cell Biology, Edinburgh , United Kingdom   Novel...... to investigate protein structure and protein-protein interactions. When applied to single proteins or small purified protein complexes, this methodology works well. However certain challenges arise when applied to more complex samples. One of the main problems is the combinatorial increase in the search space...... Aspect: Our software efficiently and correctly identifies cross-links within large protein complexes, facilitating the construction of low-resolution 3D-models and interaction networks   .Introduction Chemical cross-linking of peptides coupled with mass spectrometry emerges as a powerful method...

  16. Fast Light Optical Gyroscopes

    Science.gov (United States)

    Smith, David D.

    2015-01-01

    Next-generation space missions are currently constrained by existing spacecraft navigation systems which are not fully autonomous. These systems suffer from accumulated dead-reckoning errors and must therefore rely on periodic corrections provided by supplementary technologies that depend on line-of-sight signals from Earth, satellites, or other celestial bodies for absolute attitude and position determination, which can be spoofed, incorrectly identified, occluded, obscured, attenuated, or insufficiently available. These dead-reckoning errors originate in the ring laser gyros themselves, which constitute inertial measurement units. Increasing the time for standalone spacecraft navigation therefore requires fundamental improvements in gyroscope technologies. One promising solution to enhance gyro sensitivity is to place an anomalous dispersion or fast light material inside the gyro cavity. The fast light essentially provides a positive feedback to the gyro response, resulting in a larger measured beat frequency for a given rotation rate as shown in figure 1. Game Changing Development has been investing in this idea through the Fast Light Optical Gyros (FLOG) project, a collaborative effort which began in FY 2013 between NASA Marshall Space Flight Center (MSFC), the U.S. Army Aviation and Missile Research, Development, and Engineering Center (AMRDEC), and Northwestern University. MSFC and AMRDEC are working on the development of a passive FLOG (PFLOG), while Northwestern is developing an active FLOG (AFLOG). The project has demonstrated new benchmarks in the state of the art for scale factor sensitivity enhancement. Recent results show cavity scale factor enhancements of approx.100 for passive cavities.

  17. On-line radiochemical assay for monoamine oxidase utilizing high-performance liquid chromatography

    Energy Technology Data Exchange (ETDEWEB)

    Nissinen, E.; Linko-Loeppoenen SMae; Maennistoe P4

    1984-12-01

    A fast and sensitive assay for the determination of monoamine oxidase activity was developed. The method is based on the separation and quantitation of /sup 14/C-labeled assay products by high-performance liquid chromatography, which is interfaced directly into a flow-through radioactivity detector. This allows on-line quantitation of the radioactive compounds with picomole sensitivity. The method makes possible the complete separation and detection of the deaminated products of monoamine oxidase A and B substrates benzylamine and 5-hydroxytryptamine, respectively. This assay has been applied to the measurement of monoamine oxidase A and B activities in rat brain.

  18. Research of On-line Analytical Method of Trace Oxygen and Water in Argon

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Metal sodium has an active chemical quality. When it is used as a coolant in a fast neutron reactor, it must be protected by a cover gas argon for safety operation of the reactor. But oxygen and water in argon can produce chemical reaction with sodium. Then sodium hydroxide, sodium oxide and hydrogen can be produced. This will be harmful to the safety operation of reactor. The purpose of controlling a level of impurity in the cover gas is for controlling a level of impurity in sodium. The research is to find an on-line determining method and a sampling system to monitor

  19. Simultaneous on-line monitoring of propofol and sevoflurane in balanced anesthesia by direct resistive heating gas chromatography.

    Science.gov (United States)

    Dong, Hao; Zhang, Feng Jiang; Wang, Fu Yuan; Wang, Ying Ying; Guo, Jing; Kanhar, G M; Chen, Jing; Liu, Jun; Zhou, Chen; Yan, Min; Chen, Xing

    2017-07-14

    In balanced anesthesia, sevoflurane and propofol are often used in combination to achieve a better anesthetic effect. However, methods for on-line monitoring of concentrations of the two anesthetics in patients are still rare in clinical. This study proposed a non-invasive method utilizing a fast gas chromatograph combined with a surface acoustic wave sensor (Fast GC-SAW) to simultaneously on-line monitor sevoflurane and propofol in patients' exhaled gas. By using the direct resistive heating capillary column, the single detection time of Fast GC-SAW system was significantly shortened to 90s, as well as the size reduced to (40cm×30cm×20cm). Besides, in the calibration of sevoflurane, Fast GC-SAW system showed a good linear correlation (R(2)=0.9925, P<0.01) with gas chromatography-mass spectrometer (GC-MS), which ensured the reliability and accuracy of the Fast GC-SAW system. Finally, clinical experiments on patients under balanced anesthesia were conducted. The varied concentrations measured by Fast GC-SAW extraordinarily matched the clinical usages of these two anesthetics. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. On-line Autonomous Learning Based on Leamerg Expectation

    Institute of Scientific and Technical Information of China (English)

    李利娜

    2008-01-01

    On-line autonomous learning of College English is one of the important reforms in colleges recently.This paper aims to explore the changes of teachers'role in the new on-line setting.The article first reviews the theoretical study of learner autonomy,then makes a practical investigation into the attitude and expectation learners have on teachers through a self-designed questionnaire,and explores that teachers should make an adjustment to their role orientation and changes their roles into motivators,evaluators and resources supphers in the new on-line setting.

  1. On-line Classical Guitar Course: Blogs for Music Education

    OpenAIRE

    José Luis Navarro; Gilles Lavigne; G. Guadalupe Martínez Salgado

    2009-01-01

    This article introduces an on-line course constructed by means of a blog. The tool was the main goal of a research project titled “Develop, Implementation and evaluation of a Hybrid Course Face to face-On Line for Teaching the Beginning to Play the Classical Guitar”. This work was a three steep project in which it was implemented, applied and evaluated. The on-line course was intended to prepare the students to learn the basic principles to start in classical music with the guitar. The result...

  2. Understanding on-line community: the affordances of virtual space

    Directory of Open Access Journals (Sweden)

    Karen Ruhleder

    2002-01-01

    Full Text Available Increasing numbers of on-line venues for learning are emerging as virtual communities become more accessible and commonplace. This paper looks at one particular virtual community, an on-line degree programme at the University of Illinois, Urbana-Champaign, which offers an M.S. in Library and Information Science (called LEEP. It draws on a framework presented by Mynatt, et al. (1998, which provides a lens for talking about on-line community as a set of affordances. This framework is applied to illustrate the interactions, artefacts, and expectations that shape this community.

  3. A new on-line luminometer and beam conditions monitor using single crystal diamond sensors

    CERN Document Server

    CMS Collaboration

    2015-01-01

    Instrumentation near the beam-pipe requires extremely radiation hard sensors. Inside CMS two rings instrumented with 12 single crystal diamond sensors each are installed on both sides of the interaction point. The sensors are subdivided in two pads, and each pad is read out by a dedicated fast radiation hard ASIC in 130 nm CMOS technology. Due to the excellent time resolution collision products will be separated from machine induced background. In the backend a dead-time less histogramming unit is used, and a fast microTCA system with GHz sampling rate is under development. The detector will measure both the on-line luminosity and the background bunch-by-bunch. The performance of a prototype detector in a test-beam will be reported, and results from the operation during data taking will be presented.

  4. A new on-line luminometer and beam conditions monitor using single crystal diamond sensors

    CERN Document Server

    Karacheban, Olena

    2015-01-01

    Instrumentation near the beam-pipe requires extremely radiation hardsensors. Inside CMS two rings instrumented with 12 single crystal diamondsensors each are installed on both sides of the interaction point. Thesensors are subdivided in two pads, and each pad is read out by adedicated fast radiation hard ASIC in 130 nm CMOS technology.Due to the excellent time resolution collision products will be separatedfrom machine induced background. In the backend a dead-time lesshistogramming unit is udsed, and a fast microTCA system with GHz samplingrate is under development.The detector will measure both the on-line luminosity and the backgroundbunch-by-bunch.The performance of a prototype detector in a test-beam will be reported,and results from the operation during data taking will be presented.

  5. On-Line Trajectory Retargeting for Alternate Landing Sites Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Barron Associates, Inc. proposes to develop a novel on-line trajectory optimization approach for Reusable Launch Vehicles (RLVs) under failure scenarios, targeting...

  6. Ultra-fast determination of caffeine, dipyrone, and acetylsalicylic acid by capillary electrophoresis with capacitively coupled contactless conductivity detection and identification of degradation products.

    Science.gov (United States)

    Marra, Mariana Cardoso; Cunha, Rafael Rodrigues; Vidal, Denis Tadeu Rajh; Munoz, Rodrigo Alejandro Abarza; do Lago, Claudimir Lucio; Richter, Eduardo Mathias

    2014-01-31

    Capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C(4)D) was used for fast, simultaneous determination of dipyrone (DIP), caffeine (CAF), and acetylsalicylic acid (ASA). In the same run and in less than 1min, the degradation products from DIP and ASA were also detected. In addition, the usage of the CE-C(4)D system allowed, for the first time, the detection of methylamine as a degradation product of DIP. Capillary electrophoresis with electrospray mass spectrometry experiments were carried out in order to confirm the formation of methylamine. The limits of detection by CE-C(4)D were 5, 5, and 6μmolL(-1) for CAF, DIP, and ASA, respectively. The proposed method was applied to the analysis of these compounds in pharmaceutical formulations with similar results to those achieved by HPLC (p<0.05). Copyright © 2013 Elsevier B.V. All rights reserved.

  7. ON-LINE SCHEDULING WITH REJECTION ON IDENTICAL PARALLEL MACHINES

    Institute of Scientific and Technical Information of China (English)

    Cuixia MIAO; Yuzhong ZHANG

    2006-01-01

    In this paper, we consider the on-line scheduling of unit time jobs with rejection on m identical parallel machines. The objective is to minimize the total completion time of the accepted jobs plus the total penalty of the rejected jobs. We give an on-line algorithm for the problem with competitive ratio 1/2(2 + √3) ≈ 1.86602.

  8. From User Comments to On-line Conversations

    OpenAIRE

    Wang, Chunyan; Ye, Mao; Huberman, Bernardo A.

    2012-01-01

    We present an analysis of user conversations in on-line social media and their evolution over time. We propose a dynamic model that accurately predicts the growth dynamics and structural properties of conversation threads. The model successfully reconciles the differing observations that have been reported in existing studies. By separating artificial factors from user behaviors, we show that there are actually underlying rules in common for on-line conversations in different social media web...

  9. Directions for Future Research in On-line Distance Education

    OpenAIRE

    Alaa SADIK

    2015-01-01

    Although institutions have invested much in developing on-line environments or using already established commercial platforms, only few studies have been conducted to investigate the effectiveness of on-line courses based on empirical data (Jung and Rha, 2000). A review of the literature conducted in this study showed that most of online learning studies investigated the effectiveness of Web-based interaction or Internet conferencing on learning, not the entire learning environment. Even in t...

  10. An On-line Ferrograph for Monitoring Machine Wear

    Institute of Scientific and Technical Information of China (English)

    L(U) Xiao-jun; JING Min-qing; XIE You-bai

    2005-01-01

    In order to improve an on-line ferrograph, this paper simulates a three dimensional magnetic field distribution of an electromagnet, builds a sinking motion model of a wear particle, and investigates the motion law of wear particles under two different conditions. Both numeric results and experimental results show that the on-line ferrograph is capable of monitoring machine wear conditions by measuring the concentration and size distribution of wear particles in lubricating oil.

  11. Experimentally obtaining on-line FRA in transformers by injecting controlled pulses

    Directory of Open Access Journals (Sweden)

    Eduardo Gómez-Luna

    2013-04-01

    Full Text Available Transformer monitoring based on the operating condition (on-line test has boomed in recent years because it allows early detection of risk situations or limitations regarding use to make appropriate decisions before a failure occurs. Frequency response analysis (FRA is one of the most heavily researched techniques for on-line development; it is based on obtaining a transformer’s frequency response (admittance, impedance or transfer function in a given bandwidth. This paper presents an experimental method for obtaining the frequency response with the transformer in service by injecting controlled pulses of the voltage signal using an external electronic circuit. Once the voltage and current signals had been recorded, the wavelet transform was used via multi-resolution analysis (MRA for filtering. This led to results being obtained without noise interference from the electrical system. The transfer function was obtained in terms of impedance, using the fast Fourier transform (FFT. The proposed method represented an alternative in solving some problems arising from the on-line FRA technique such as filtering and results’ repeatability. The tests involved a 5-kVA 1150/345 V three-phase transformer and a 3-kVA, 7620/240 V single-phase transformer in the Universidad del Valle’s High Voltage Laboratory.

  12. High resolution LC-ESI-TOF-mass spectrometry method for fast separation, identification, and quantification of 12 isoflavones in soybeans and soybean products.

    Science.gov (United States)

    Lee, Mi Jin; Chung, Ill-Min; Kim, Hunjung; Jung, Mun Yhung

    2015-06-01

    A high resolution LC-ESI-TOF-MS analytical method was established for the rapid isolation, identification, and quantification of 12 isoflavones in soybean and soybean products. Individual isoflavones were identified on the basis of the accurate mass data of their respective protonated mass ions, Na or K adduct ions, fragment ions, and isotope ion patterns. The protonated mass ions of isoflavones were extracted for their quantification in soybean products. Twelve different isoflavones in the soybean products were fully separated, identified and quantified within 12min separation time. The established LC-TOF/MS was an effective analytical method for the simultaneous characterization and quantification of isoflavones with exceptionally short analytical time, high selectivity, a high linearity (r(2)>0.992) in a wide range, low LOD and LOQ, high precision, inter-and intra-day repeatability, and no significant matrix effect. Furthermore, it requires simple sample preparation procedure (solvent extraction, dilution, and syringe filtration).

  13. Automated Fast Screening Method for Cocaine Identification in Seized Drug Samples Using a Portable Fourier Transform Infrared (FT-IR) Instrument.

    Science.gov (United States)

    Mainali, Dipak; Seelenbinder, John

    2016-05-01

    Quick and presumptive identification of seized drug samples without destroying evidence is necessary for law enforcement officials to control the trafficking and abuse of drugs. This work reports an automated screening method to detect the presence of cocaine in seized samples using portable Fourier transform infrared (FT-IR) spectrometers. The method is based on the identification of well-defined characteristic vibrational frequencies related to the functional group of the cocaine molecule and is fully automated through the use of an expert system. Traditionally, analysts look for key functional group bands in the infrared spectra and characterization of the molecules present is dependent on user interpretation. This implies the need for user expertise, especially in samples that likely are mixtures. As such, this approach is biased and also not suitable for non-experts. The method proposed in this work uses the well-established "center of gravity" peak picking mathematical algorithm and combines it with the conditional reporting feature in MicroLab software to provide an automated method that can be successfully employed by users with varied experience levels. The method reports the confidence level of cocaine present only when a certain number of cocaine related peaks are identified by the automated method. Unlike library search and chemometric methods that are dependent on the library database or the training set samples used to build the calibration model, the proposed method is relatively independent of adulterants and diluents present in the seized mixture. This automated method in combination with a portable FT-IR spectrometer provides law enforcement officials, criminal investigators, or forensic experts a quick field-based prescreening capability for the presence of cocaine in seized drug samples.

  14. Object-Oriented Control System Design Using On-Line Training of Artificial Neural Networks

    Science.gov (United States)

    Rubaai, Ahmed

    1997-01-01

    This report deals with the object-oriented model development of a neuro-controller design for permanent magnet (PM) dc motor drives. The system under study is described as a collection of interacting objects. Each object module describes the object behaviors, called methods. The characteristics of the object are included in its variables. The knowledge of the object exists within its variables, and the performance is determined by its methods. This structure maps well to the real world objects that comprise the system being modeled. A dynamic learning architecture that possesses the capabilities of simultaneous on-line identification and control is incorporated to enforce constraints on connections and control the dynamics of the motor. The control action is implemented "on-line", in "real time" in such a way that the predicted trajectory follows a specified reference model. A design example of controlling a PM dc motor drive on-line shows the effectiveness of the design tool. This will therefore be very useful in aerospace applications. It is expected to provide an innovative and noval software model for the rocket engine numerical simulator executive.

  15. Application of an asymmetric helical tube reactor for fast identification of gene transcripts of pathogenic viruses by micro flow-through PCR.

    Science.gov (United States)

    Hartung, R; Brösing, A; Sczcepankiewicz, G; Liebert, U; Häfner, N; Dürst, M; Felbel, J; Lassner, D; Köhler, J M

    2009-06-01

    We have established a fast PCR-based micro flow-through process consisting of a helical constructed tube reactor. By this approach we can detect transcripts of measles and human papilloma virus (HPV) by continuous flow allowing for reverse transcription (RT) and amplification of cDNA. The micro reaction system consisted of two columnar reactors for thermostating the different reaction zones of the RT process and the amplification. The PCR reactor was built by asymmetric heating sections thus realizing different residence times and optimal conditions for denaturation, annealing and elongation. The system concept is based on low electrical power consumption (50-120 W) and is suited for portable diagnostic applications. The samples were applied in form of micro fluidic segments with single volumes between 65 and 130 nL injected into an inert carrier liquid inside a Teflon FEP tube with an inner diameter of 0.5 mm. Optimal amplification for template lengths of 292 bp (lambda-DNA), 127 bp (measles virus) and 95 bp (HPV) was achieved by maximal cycle times of 75 s.

  16. COMUNICAREA ON-LINE PRIN INTERMEDIUL BLOG-URILOR (ON-LINE COMMUNICATION THROUGH BLOGS

    Directory of Open Access Journals (Sweden)

    Cristian Morozan

    2006-05-01

    Full Text Available In today’s society blog-writing represents an activity through which people make public their observations, reflections, reactions and dilemmas to the general public or to a smaller category if the information is confidential. The blogs represent a fast and effective way of using IT and the internet, and have a positive effect in PR, journalism, marketing, information management and virtual communities. We would like to emphasize that they are being used extensively especially in public relations, companies using them in order to interact directly with their public, be it internal or external and in order to create the image or reputation of their spokes-person. In our country, “the blogosphere” (the sum of all blogs and their connection paths is made up of web-logs on various themes written by Romanians from various locations in the world and has become, just like in other countries, a “supplement” to the traditional mass-media.

  17. SVSI: fast and powerful set-valued system identification approach to identifying rare variants in sequencing studies for ordered categorical traits.

    Science.gov (United States)

    Bi, Wenjian; Kang, Guolian; Zhao, Yanlong; Cui, Yuehua; Yan, Song; Li, Yun; Cheng, Cheng; Pounds, Stanley B; Borowitz, Michael J; Relling, Mary V; Yang, Jun J; Liu, Zhifa; Pui, Ching-Hon; Hunger, Stephen P; Hartford, Christine M; Leung, Wing; Zhang, Ji-Feng

    2015-07-01

    In genetic association studies of an ordered categorical phenotype, it is usual to either regroup multiple categories of the phenotype into two categories and then apply the logistic regression (LG), or apply ordered logistic (oLG), or ordered probit (oPRB) regression, which accounts for the ordinal nature of the phenotype. However, they may lose statistical power or may not control type I error due to their model assumption and/or instable parameter estimation algorithm when the genetic variant is rare or sample size is limited. To solve this problem, we propose a set-valued (SV) system model to identify genetic variants associated with an ordinal categorical phenotype. We couple this model with a SV system identification algorithm to identify all the key system parameters. Simulations and two real data analyses show that SV and LG accurately controlled the Type I error rate even at a significance level of 10(-6) but not oLG and oPRB in some cases. LG had significantly less power than the other three methods due to disregarding of the ordinal nature of the phenotype, and SV had similar or greater power than oLG and oPRB. We argue that SV should be employed in genetic association studies for ordered categorical phenotype.

  18. Sport Management Taught On-Line: A Discussion

    Directory of Open Access Journals (Sweden)

    William F. Stier Jr

    2009-01-01

    Full Text Available An introduction to the world of on-line courses (distance education/learning is presented. In addition, the world of on-line learning, as it pertains to sport management, is examined within the framework of (a pedagogy, (b finances,(c assessment, and (d choosing to transition from the traditional classroom to on-line learning. Pertinent points relative to each of the four categories are presented from the literature. In an effort to stimulate thought and discussion to the subject of on-line learning for sport management programs/courses the authors provide their reactions to the literature points by presenting their comments/reactions from a sport management perspective. Sport management professors and administrators are encouraged to critically examine the feasibility of such on-line courses (distance education/learning within their own curricula while maintaining an appropriate framework revolving around sound theoretical instructional strategies, methods as well as appropriate use of instructional tools, including but not limited to, computersand the WWW.

  19. Not So Fast: Hippocampal Amnesia Slows Word Learning Despite Successful Fast Mapping

    OpenAIRE

    Warren, David E.; Duff, Melissa C.

    2014-01-01

    The human hippocampus is widely believed to be necessary for the rapid acquisition of new declarative relational memories. However, processes supporting on-line inferential word use (“fast mapping”) may also exercise a dissociable learning mechanism and permit rapid word learning without the hippocampus (Sharon et al. (2011) Proc Natl Acad Sci USA 108:1146–1151). We investigated fast mapping in severely amnesic patients with hippocampal damage (N = 4), mildly amnesic patients (N = 6), and hea...

  20. 利用近红外高光谱图像技术快速鉴别西瓜种子品种%Fast identification of watermelon seed variety using near infrared hyperspectral imaging technology

    Institute of Scientific and Technical Information of China (English)

    张初; 刘飞; 孔汶汶; 章海亮; 何勇

    2013-01-01

    , with an identification rate of 91.57% in the calibration set and 78.95% in the prediction set. SPA-BPNN models showed relatively worse results than GA-PLS-BPNN models with the same spectral preprocessing methods. The SG-GA-PLS-BPNN model obtained the best performance among all BPNN models, with an identification rate of 92.77% in the calibration set and 86.84%in the prediction set. Compared with the PLS-DA models and the BPNN models, ELM models obtained the best results. All ELM models obtained an identification rate over 90%in the calibration set and the prediction set, and the SG-SPA-ELM model, SG-GA-PLS-ELM model, and WT-SPA-ELM model obtained the identification rate of 100%of calibration and prediction. The overall results showed that BPNN and ELM models performed better than PLS-DA models, and the ELM models with the selected wavelengths based on SG preprocessed spectra obtained the best results, with 100%classification accuracy for both the calibration set and the prediction set. The SG preprocessing method showed the best performance in all PLS-DA, BPNN, and ELM models. The results indicated that it was feasible to use near-infrared hyperspectral imaging to identify the watermelon seed varieties, and near-infrared hyperspectral imaging provided an alternate way of rapid identification of watermelon seed variety. ELM, as a single hidden layer feed-forward network, was an effective classification method in watermelon seed cultivar identification. Moreover, the results in this paper showed the great potential of hyperspectral imaging in the seed industry for on-line identification of seed cultivars and detection of the seed quality parameters.%为了研究采用近红外高光谱图像技术对西瓜种子品种快速无损鉴别的可行性,该文采用近红外高光谱图像技术,通过提取西瓜种子的光谱反射率,结合Savitzky-Golay (SG)平滑算法,经验模态分解算法(empirical mode decomposition

  1. On-line Payment System Survey – eCash

    Directory of Open Access Journals (Sweden)

    Marius Popa

    2009-12-01

    Full Text Available The paper presents the main aspects regarding an on-line payment system. Some characteristics of such system are presented and an existing system is analyzed. On its fundamental sense, the electronic commerce is a concept that represents the purchase and sale process or exchange of products, services, information, using o computer network, inclusively the Internet. In the most part of the cases, the electronic commerce imply on-line payments that lead to creation of some kinds of electronic money and some specific payment systems. There are described the some electronic payment mechanisms and the architecture and the functions of the on-line payment system E-Cash are depicted.

  2. A Hybrid On-line Verification Method of Relay Setting

    Science.gov (United States)

    Gao, Wangyuan; Chen, Qing; Si, Ji; Huang, Xin

    2017-05-01

    Along with the rapid development of the power industry, grid structure gets more sophisticated. The validity and rationality of protective relaying are vital to the security of power systems. To increase the security of power systems, it is essential to verify the setting values of relays online. Traditional verification methods mainly include the comparison of protection range and the comparison of calculated setting value. To realize on-line verification, the verifying speed is the key. The verifying result of comparing protection range is accurate, but the computation burden is heavy, and the verifying speed is slow. Comparing calculated setting value is much faster, but the verifying result is conservative and inaccurate. Taking the overcurrent protection as example, this paper analyses the advantages and disadvantages of the two traditional methods above, and proposes a hybrid method of on-line verification which synthesizes the advantages of the two traditional methods. This hybrid method can meet the requirements of accurate on-line verification.

  3. On-line laser spectroscopy with thermal atomic beams

    CERN Document Server

    Thibault, C; De Saint-Simon, M; Duong, H T; Guimbal, P; Huber, G; Jacquinot, P; Juncar, P; Klapisch, Robert; Liberman, S; Pesnelle, A; Pillet, P; Pinard, J; Serre, J M; Touchard, F; Vialle, J L

    1981-01-01

    On-line high resolution laser spectroscopy experiments have been performed in which the light from a CW tunable dye laser interacts at right angles with a thermal atomic beam. /sup 76-98/Rb, /sup 118-145 /Cs and /sup 208-213/Fr have been studied using the ionic beam delivered by the ISOLDE on-line mass separator at CERN while /sup 30-31/Na and /sup 38-47/K have been studied by setting the apparatus directly on-line with the PS 20 GeV proton beam. The principle of the method is briefly explained and some results concerning nuclear structure are given. The hyperfine structure, spins and isotope shifts of the alkali isotopes and isomers are measured. (8 refs).

  4. Strengthening weak ties through on-line gaming

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana Virginia; Kirchner, Kathrin

    On-line gaming became widespread in the last couple of years. The aim of the research presented in the paper is to figure out to what extent does game playing helps to strengthen weak ties and what additional factors influence this process. The approach is rather exploratory – some factors...... are grounded in theory, some are new. These factors are age, gender, place of origin, number of their Facebook connections (friends in Facebook terminology), the amount of time they are on Facebook, the amount of time they keep the Facebook site open, the amount of time they play on-line games, and the reasons...... for starting to play on-line games. Regarding the latter, we chose to focus only on escapist reasons....

  5. On-Line Voltage Stability Assessment based on PMU Measurements

    DEFF Research Database (Denmark)

    Garcia-Valle, Rodrigo; P. Da Silva, Luiz C.; Nielsen, Arne Hejde

    2009-01-01

    through statistic analysis. During the off-line analysis, a memory of high-risk situations following a pre-defined voltage stability criterion is obtained. Thereafter, basic statistics analyses are applied resulting in the definition of voltage regions. During on-line operation, voltage magnitudes......This paper presents a method for on-line monitoring of risk voltage collapse based on synchronised phasor measurement. As there is no room for intensive computation and analysis in real-time, the method is based on the combination of off-line computation and on-line monitoring, which are correlated...... of critical buses obtained by phasor measurements are monitored in relation to the risk regions. Comprehensive studies demonstrate that the proposed method could assist operators to avoid voltage collapse events, by taking preventive or emergency actions....

  6. On-line tribochemical strengthening of gear surface

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    It has been found that under favorable friction conditions some antiwear elements inlubricating additives can permeate into subsurface of metal which can strengthens the friction sur-faces and improves anti-wear capacity of frication pairs. It is in many ways similar to chemical heattreatment. A new concept, technology of on-line strengthening, was logically put forward. Based oncurrent gear surface treatment technology, the on-line strengthen of gear surface is proposed. Itsdesign method is established. Based on it, the on-line strengthen of gear is achieved on CL-100gear test machine. A new method is put forward for strengthen treatment of gear surface. Andthree kinds of surface film were suggested.

  7. APPROACH TO FAULT ON-LINE DETECTION AND DIAGNOSIS BASED ON NEURAL NETWORKS FOR ROBOT IN FMS

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    Based on radial basis function (RBF) neural networks, the healthy working model of each sub-system of robot in FMS is established. A new approach to fault on-line detection and diagnosis according to neural networks model is presented. Fault double detection based on neural network model and threshold judgement and quick fault identification based on multi-layer feedforward neural networks are applied, which can meet quickness and reliability of fault detection and diagnosis for robot in FMS.

  8. Why do People Stop Playing On-Line Games?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    2012-01-01

    The recent initial public offering of shares of Zynga, probably the most important on-line game provider, drew interest of potential investors but also of general public to their business model. What the most interested people learned so far is that if Zynga had not changed their accounting...... practice, they would be in red numbers for several months already. This is most likely caused by people stopping to play their games. This paper provides an estimate of what proportion of people, who played on-line games, already stopped playing them. Additionally, it analyzed the reasons why people...

  9. On-Line Generation of 3D-Waves

    DEFF Research Database (Denmark)

    Frigaard, Peter

    1992-01-01

    The paper describes the technique of filtering white noise for on-line generation of 3D-waves on a small computer in the laboratory. The wave generation package is implemented and tested in the 3D-wave basin at the University of Aalborg.......The paper describes the technique of filtering white noise for on-line generation of 3D-waves on a small computer in the laboratory. The wave generation package is implemented and tested in the 3D-wave basin at the University of Aalborg....

  10. The User-friendly On-Line Diffusion Chamber

    CERN Document Server

    Aviles Acosta, Jaime

    2015-01-01

    The On-Line Diffusion Chamber is a stand-alone apparatus built to carry out short-live radiotracer diffusion studies. The availability of the on-demand production of isotopes in the ISOLDE facility, and the design of the apparatus to streamline the implantation process, annealing treatment, ion gun ablation with a tape transport system, and radiation intensity measurement with a Ge gamma detector all in the same apparatus, gives the On-Line Diffusion Chamber a unique ability to studies with short-lived radioisotopes or isomer states that are not possible in any other facility in the world.

  11. On-line measurement of heat of combustion

    Science.gov (United States)

    Chaturvedi, S. K.; Chegini, H.

    1988-01-01

    An experimental method for an on-line measurement of heat of combustion of a gaseous hydrocarbon fuel mixture of unknown composition is developed. It involves combustion of a test gas with a known quantity of air to achieve a predetermined oxygen concentration level in the combustion products. This is accomplished by a feedback controller which maintains the gas volumetric flow rate at a level consistent with the desired oxygen concentration in the products. The heat of combustion is determined from a known correlation with the gas volumetric flow rate. An on-line microcomputer accesses the gas volumetric flow data, and displays the heat of combustion values at desired time intervals.

  12. 5th Computer Science On-line Conference

    CERN Document Server

    Senkerik, Roman; Oplatkova, Zuzana; Silhavy, Petr; Prokopova, Zdenka

    2016-01-01

    This volume is based on the research papers presented in the 5th Computer Science On-line Conference. The volume Artificial Intelligence Perspectives in Intelligent Systems presents modern trends and methods to real-world problems, and in particular, exploratory research that describes novel approaches in the field of artificial intelligence. New algorithms in a variety of fields are also presented. The Computer Science On-line Conference (CSOC 2016) is intended to provide an international forum for discussions on the latest research results in all areas related to Computer Science. The addressed topics are the theoretical aspects and applications of Computer Science, Artificial Intelligences, Cybernetics, Automation Control Theory and Software Engineering.

  13. Comparison of nested, multiplex, qPCR; FISH; SeptiFast and blood culture methods in detection and identification of bacteria and fungi in blood of patients with sepsis.

    Science.gov (United States)

    Gosiewski, Tomasz; Flis, Agnieszka; Sroka, Agnieszka; Kędzierska, Anna; Pietrzyk, Agata; Kędzierska, Jolanta; Drwiła, Rafał; Bulanda, Małgorzata

    2014-12-11

    Microbiological diagnosis of sepsis relies primarily on blood culture data. This study compares four diagnostic methods, i.e. those developed by us: nested, multiplex, qPCR (qPCR) and FISH with commercial methods: SeptiFast (Roche) (SF) and BacT/ALERT® 3D blood culture system (bioMérieux). Blood samples were derived from adult patients with clinical symptoms of sepsis, according to SIRS criteria, hospitalized in the Intensive Care Unit. Using qPCR, FISH, SF, and culture, microbial presence was found in 71.8%, 29.6%, 25.3%, and 36.6% of samples, respectively. It was demonstrated that qPCR was significantly more likely to detect microorganisms than the remaining methods; qPCR confirmed the results obtained with the SF kit in all cases wherein bacteria were detected with simultaneous confirmation of Gram-typing. All data collected through the FISH method were corroborated by qPCR. The qPCR and FISH methods described in this study may constitute alternatives to blood culture and to the few existing commercial molecular assays since they enable the detection of the majority of microbial species, and the qPCR method allows their identification in a higher number of samples than the SF test. FISH made it possible to show the presence of microbes in a blood sample even before its culture.

  14. On-Line Learning and the Implications for School Design

    Science.gov (United States)

    Stack, Greg

    2011-01-01

    "Disrupting Class," published in 2008, is the story of how disruptive innovation, innovation that changes the business model organizations, will fundamentally change the American school system. The book's most startling prediction is that half of all high school classes will be on-line by 2019. In considering these predictions, the author began to…

  15. On-line multidimensional separation systems for peptide analysis

    NARCIS (Netherlands)

    Stroink, T.

    2005-01-01

    Today, there is an increasing interest in selective and sensitive analysis of proteins and peptides with a relatively high speed. The first chapter of this thesis describes several strategies for the on-line multidimensional analysis of peptides and proteins in biological samples. This overview of t

  16. On-line probabilistic classification with particle filters

    DEFF Research Database (Denmark)

    Højen-Sørensen, Pedro; de Freitas, N.; Fog, Torben L.

    2000-01-01

    We apply particle filters to the problem of on-line classification with possibly overlapping classes. This allows us to compute the probabilities of class membership as the classes evolve. Although we adopt neural network classifiers, the work can be extended to any other parametric classification...

  17. Personal Assistant for onLine Services: Addressing human factors

    NARCIS (Netherlands)

    Lindenberg, J.; Nagata, S.F.; Neerincx, M.A.

    2003-01-01

    The Personal Assistant for onLine Services (PALS) project aims at substantially improving the user experience of mobile internet services. It focuses on a generic solution: a personal assistant, which attunes the interaction to the momentary user needs and use context (e.g. adjusting the

  18. Efficiently Building On-line Tools for Distributed Heterogeneous Environments

    Directory of Open Access Journals (Sweden)

    Günther Rackl

    2002-01-01

    Full Text Available Software development is getting more and more complex, especially within distributed middleware-based environments. A major drawback during the overall software development process is the lack of on-line tools, i.e. tools applied as soon as there is a running prototype of an application. The MIMO MIddleware MOnitor provides a solution to this problem by implementing a framework for an efficient development of on-line tools. This paper presents a methodology for developing on-line tools with MIMO. As an example scenario, we choose a distributed medical image reconstruction application, which represents a test case with high performance requirements. Our distributed, CORBA-based application is instrumented for being observed with MIMO and related tools. Additionally, load balancing mechanisms are integrated for further performance improvements. As a result, we obtain an integrated tool environment for observing and steering the image reconstruction application. By using our rapid tool development process, the integration of on-line tools shows to be very convenient and enables an efficient tool deployment.

  19. Developing an On-Line Interactive Health Psychology Module

    Science.gov (United States)

    Upton, Dominic; Cooper, Carol

    2006-01-01

    On-line teaching material in health psychology was developed which ensured a range of students could access appropriate material for their course and level of study. This material has been developed around the concept of smaller "content chunks" which can be combined into whole units of learning (topics), and ultimately, a module. On the basis of…

  20. Why do People Stop playing On-Line Games?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    2012-01-01

    The recent initial public offering of shares of Zynga, probably the most important on-line game provider, drew interest of potential investors but also of general public to their business model. What the most interested people learned so far is that if Zynga had not changed their accounting...

  1. On-line fuzzy logic control of tube bending

    Science.gov (United States)

    Lieh, Junghsen; Li, Wei Jie

    2005-11-01

    This paper describes the simulation and on-line fuzzy logic control of tube bending. By combining elasticity and plasticity theories, a conventional model was developed. The results from simulation were compared with those obtained from testing. The experimental data reveal that there exists certain level of uncertainty and nonlinearity in tube bending, and its variation could be significant. To overcome this, a on-line fuzzy logic controller with self-tuning capabilities was designed. The advantages of this on-line system are (1) its computational requirement is simple in comparison with more algorithmic-based controllers, and (2) the system does not need prior knowledge of material characteristics. The device includes an AC motor, a servo controller, a forming mechanism, a 3D optical sensor, and a microprocessor. This automated bending machine adopts primary and secondary errors between the actual response and desired output to conduct on-line rule reasoning. Results from testing show that the spring back angle can be effectively compensated by the self- tuning fuzzy system in a real-time fashion.

  2. The dynamics of on-line principal component analysis

    NARCIS (Netherlands)

    Biehl, M.; Schlösser, E.

    1998-01-01

    The learning dynamics of an on-line algorithm for principal component analysis is described exactly in the thermodynamic limit by means of coupled ordinary differential equations for a set of order parameters. It is demonstrated that learning is delayed significantly because existing symmetries amon

  3. On-Line Learning and the Implications for School Design

    Science.gov (United States)

    Stack, Greg

    2011-01-01

    "Disrupting Class," published in 2008, is the story of how disruptive innovation, innovation that changes the business model organizations, will fundamentally change the American school system. The book's most startling prediction is that half of all high school classes will be on-line by 2019. In considering these predictions, the author began to…

  4. Specialization processes in on-line unsupervised learning

    NARCIS (Netherlands)

    Biehl, M.; Freking, A.; Reents, G.; Schlösser, E.

    1998-01-01

    From the recent analysis of supervised learning by on-line gradient descent in multilayered neural networks it is known that the necessary process of student specialization can be delayed significantly. We demonstrate that this phenomenon also occurs in various models of unsupervised learning. A sol

  5. On-line sample treatment - Capillary gas chromatography

    NARCIS (Netherlands)

    Goosens, EC; de Jong, D; de Jong, GJ; Brinkman, UAT

    1998-01-01

    Sample pretreatment is often the bottleneck of a trace level analytical procedure. In order to increase performance, increasing attention is therefore being devoted to combining sample pretreatment on-line with the separation technique that has to be used. In the present review, a variety of procedu

  6. A New On-Line Resource for Psycholinguistic Studies

    Science.gov (United States)

    Szekely, Anna; Jacobsen, Thomas; D'Amico, Simona; Devescovi, Antonella; Andonoa, Elena; Herron, Daniel; Lu, Ching Ching; Pechmann, Thomas; Pleh, Csaba; Wicha, Nicole; Federmeier, Kara; Gerdjikova, Irina; Gutierrez, Gabriel; Hung, Daisy, Hsu, Jeanne; Iyer, Gowri; Kohnert, Kathryn; Mehotcheva, Teodora; Orozco-Figueroa, Araceli; Tzeng, Angela; Tzeng, Ovid; Arevalo, Analia; Vargha, Andras; Butler, Andrew C.; Buffington, Robert; Bates, Elizabeth

    2004-01-01

    Picture naming is a widely used technique in psycholinguistic studies. Here, we describe new on-line resources that our project has compiled and made available to researchers on the world wide web at http://crl.ucsd.edu/~aszekely/ipnp/. The website provides access to a wide range of picture stimuli and related norms in seven languages. Picture…

  7. ADAPTIVE CONTEXT PROCESSING IN ON-LINE HANDWRITTEN CHARACTER RECOGNITION

    NARCIS (Netherlands)

    Iwayama, N.; Ishigaki, K.

    2004-01-01

    We propose a new approach to context processing in on-line handwritten character recognition (OLCR). Based on the observation that writers often repeat the strings that they input, we take the approach of adaptive context processing. (ACP). In ACP, the strings input by a writer are automatically

  8. The Lesson Observation On-Line (Evidence Portfolio) Platform

    Science.gov (United States)

    Cooper, David G.

    2015-01-01

    At a time when teacher training is being moved to school-based programmes it is important to engage in a research-informed dialogue about creating more distinctive, and cost-effective 21st century models of teacher training. Three years ago I began feasibility field testing the Lesson Observation On-line (Evidence Portfolio) Platform [LOOP]…

  9. On-line EM algorithm for the normalized gaussian network.

    Science.gov (United States)

    Sato, M; Ishii, S

    2000-02-01

    A normalized gaussian network (NGnet) (Moody & Darken, 1989) is a network of local linear regression units. The model softly partitions the input space by normalized gaussian functions, and each local unit linearly approximates the output within the partition. In this article, we propose a new on-line EMalgorithm for the NGnet, which is derived from the batch EMalgorithm (Xu, Jordan, &Hinton 1995), by introducing a discount factor. We show that the on-line EM algorithm is equivalent to the batch EM algorithm if a specific scheduling of the discount factor is employed. In addition, we show that the on-line EM algorithm can be considered as a stochastic approximation method to find the maximum likelihood estimator. A new regularization method is proposed in order to deal with a singular input distribution. In order to manage dynamic environments, where the input-output distribution of data changes over time, unit manipulation mechanisms such as unit production, unit deletion, and unit division are also introduced based on probabilistic interpretation. Experimental results show that our approach is suitable for function approximation problems in dynamic environments. We also apply our on-line EM algorithm to robot dynamics problems and compare our algorithm with the mixtures-of-experts family.

  10. On-Line Synthesis and Analysis by Mass Spectrometry

    Science.gov (United States)

    Bain, Ryan M.; Pulliam, Christopher J.; Raab, Shannon A.; Cooks, R. Graham

    2015-01-01

    In this laboratory experiment, students learn how to use ESI to accelerate chemical synthesis and to couple it with on-line mass spectrometry for structural analysis. The Hantzsch synthesis of symmetric 1,4-dihydropyridines is a classic example of a one-pot reaction in which multiple intermediates can serve to indicate the progress of the reaction…

  11. Investigating on-line pornography at the University of Johannesburg

    Directory of Open Access Journals (Sweden)

    P. Laughton

    2008-01-01

    Full Text Available The on-line user of today has access to a vast collection of information resources. In addition, the developments in Internet and Web technologies have made it even easier for surfers to anonymously get access to on-line pornography. The purpose of this research was to investigate the extent to which access to on-line pornography at the University of Johannesburg can be managed. For the empirical part of this research 1037 questionnaires were proportionally distributed to and completed by students on all five campuses of the university. The questionnaire consisted of four sections: biographical information; university computer facility usage; university acceptable use policy; and personal experience with university computer facilities. The gender distribution for the sample was almost even, with a total of 49,4% male participants and 50,6% female, with the largest grouping of respondents (61,6% aged between 19 years and 21 years. Of the respondents, 36,7% indicated that exposure to unsolicited pornography did not bother them. When asked to what extent students should have access to pornography, 60,5% stated 'None' while 32,6% believed that 'Restricted' access should be granted for research purposes and 6,9% believed that students should be granted 'Total' access to pornography. Results from the research will be used to manage access to on-line resources at the University of Johannesburg better.

  12. Investigating on-line pornography at the University of Johannesburg

    Directory of Open Access Journals (Sweden)

    P. Laughton

    2007-12-01

    Full Text Available The on-line user of today has access to a vast collection of information resources. In addition, the developments in Internet and Web technologies have made it even easier for surfers to anonymously get access to on-line pornography. The purpose of this research was to investigate the extent to which access to on-line pornography at the University of Johannesburg can be managed. For the empirical part of this research 1037 questionnaires were proportionally distributed to and completed by students on all five campuses of the university. The questionnaire consisted of four sections: biographical information; university computer facility usage; university acceptable use policy; and personal experience with university computer facilities. The gender distribution for the sample was almost even, with total of 49,4% male participants and 50,6% female, with the largest grouping of respondents(61,6% aged between 19 years and 21 years. Of the respondents, 36,7% indicated that exposure to unsolicited pornography did not bother them. When asked to what extent students should have access to pornography, 60,5% stated 'None' while 32,6% believed that 'Restricted' access should be granted for research purposes and 6,9% believed that students should be granted 'Total' access to pornography. Results from the research will be used to manage access to on-line resources at the University of Johannesburg better.

  13. On-Line NDE for Advanced Reactor Designs

    Science.gov (United States)

    Nakagawa, N.; Inanc, F.; Thompson, R. B.; Junker, W. R.; Ruddy, F. H.; Beatty, J. M.; Arlia, N. G.

    2003-03-01

    This expository paper introduces the concept of on-line sensor methodologies for monitoring the integrity of components in next generation power systems, and explains general benefits of the approach, while describing early conceptual developments of suitable NDE methodologies. The paper first explains the philosophy behind this approach (i.e. the design-for-inspectability concept). Specifically, we describe where and how decades of accumulated knowledge and experience in nuclear power system maintenance are utilized in Generation IV power system designs, as the designs are being actively developed, in order to advance their safety and economy. Second, we explain that Generation IV reactor design features call for the replacement of the current outage-based maintenance by on-line inspection and monitoring. Third, the model-based approach toward design and performance optimization of on-line sensor systems, using electromagnetic, ultrasonic, and radiation detectors, will be explained. Fourth, general types of NDE inspections that are considered amenable to on-line health monitoring will be listed. Fifth, we will describe specific modeling developments to be used for radiography, EMAT UT, and EC detector design studies.

  14. On-Line Synthesis and Analysis by Mass Spectrometry

    Science.gov (United States)

    Bain, Ryan M.; Pulliam, Christopher J.; Raab, Shannon A.; Cooks, R. Graham

    2015-01-01

    In this laboratory experiment, students learn how to use ESI to accelerate chemical synthesis and to couple it with on-line mass spectrometry for structural analysis. The Hantzsch synthesis of symmetric 1,4-dihydropyridines is a classic example of a one-pot reaction in which multiple intermediates can serve to indicate the progress of the reaction…

  15. Why do People Stop Playing On-Line Games?

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    2012-01-01

    The recent initial public offering of shares of Zynga, probably the most important on-line game provider, drew interest of potential investors but also of general public to their business model. What the most interested people learned so far is that if Zynga had not changed their accounting...

  16. On-line survivable routing in WDM networks

    NARCIS (Netherlands)

    Beshir, A.A.; Kuipers, F.A.; Van Mieghem, P.F.A.; Orda, A.

    2009-01-01

    In WDM networks, survivable routing and wavelength assignment (SRWA) involves assigning link-disjoint primary and backup lightpaths. In the on-line SRWA problem, a sequence of requests arrive and each request is either accepted or rejected based only on the input sequence seen so far. For special

  17. On-line Survivable Routing in WDM Networks

    NARCIS (Netherlands)

    Beshir, A.A.; Kuipers, F.A.; Van Mieghem, P.; Orda, A.

    In WDM networks, survivable routing and wavelength assignment (SRWA) involves assigning link-disjoint primary and backup lightpaths. In the on-line SRWA problem, a sequence of requests arrive and each request is either accepted or rejected based only on the input sequence seen so far. For special

  18. IOOS Data Portals and Uniform On-line Browse Capabilities

    Science.gov (United States)

    Howard, M.; Currier, R. D.; Kobara, S.; Gayanilo, F.

    2015-12-01

    The Gulf of Mexico Coastal Ocean Observing System Regional Association (GCOOS-RA) is one of eleven Regional Associations organized under the NOAA-led U.S. Integrated Ocean Observing System (IOOS) Program Office. Each of the RAs operate standards-based regional data portals designed to aggregate near real-time and historical observed data and modeled outputs from distributed providers and to offer these and derived products in standardized ways to a diverse set of users. The RA's portals are based on the IOOS Data and Communications Plan which describes the functional elements needed for an interoperable system. One of these elements is called "Uniform On-line Browse" which is an informational service designed primarily to visualize the inventory of a portal. An on-line browse service supports the end user's need to discover what parameters are available, to learn the spatial and temporal extend of the holdings, and to examine the character of the data (e.g, variability, gappiness, etc). These pieces of information help the end user decide if the data are fit for his/her purpose and to construct valid data requests. Note that on-line browse is a distinctly different activity than data analysis because it seeks to yield knowledge about the inventory and not about what the data mean. "Uniform" on-line browse is a service that takes advantage of the standardization of the data portal's data access points. Most portals represent station locations on a map. This is a view of the data inventory but these plots are rarely generated by pulling data through the standards-based services offered to the end users but through methods only available to the portal programmers. This work will present results of Uniform On-line browse tools developed within GCOOS-RA and their applicability to other RA portals.

  19. Mentoring Narratives ON-LINE:Teaching the Principalship

    Directory of Open Access Journals (Sweden)

    Allison I. Griffith

    2002-05-01

    Full Text Available The need to develop new models for preparation of school administrators has been a prominent concern in educational discourse in the last decade. Having been criticized for the inadequate preparation of the school leadership cadre, academic departments responsible for training future school administrators have had to revisit their approaches and to reframe their teaching philosophies to ensure the readiness of their graduates for the challenges and complexities of school leadership. This article reports on the new model of principals' training that has been used in York University's Principals' Qualification Program (PQP from the late 1990s onward. One component of the program brings traditional case methodology into a computer-mediated/on-line environment. The on-line cases are narratives from the everyday lives of the Ontario school administrators who serve as mentors in the on-line environment. Situating our discussion within the context of the rapidly changing educational landscape of Ontario, we focus on the PQP model to explore experientially generated case narratives as one method for teaching and learning the work of the local school administrator. We focus particularly on the teaching and learning embedded in computer-mediated or on-line case narratives used in training teachers for school leadership. We argue that the complexities of school leadership—the social, cultural, relational, ethical and moral context of school leadership—can be taught effectively through the reflective processes of on-line case narratives. We seek to contribute to the ongoing dialogue on the potential of new pedagogies and new technologies to help prepare the competent and responsible leaders for tomorrow's schools.

  20. On-line coupled LC-LC-GC for irradiation detection in complex lipid matrices

    Energy Technology Data Exchange (ETDEWEB)

    Schulzki, G. (Laboratory Group, Irradiation of Foods and Pharmaceuticals, Alternative Techniques, Inst. for Social Medicine and Epidemiology, Federal Health Office (BGA), Berlin (Germany)); Spiegelberg, A. (Laboratory Group, Irradiation of Foods and Pharmaceuticals, Alternative Techniques, Inst. for Social Medicine and Epidemiology, Federal Health Office (BGA), Berlin (Germany)); Helle, N. (Laboratory Group, Irradiation of Foods and Pharmaceuticals, Alternative Techniques, Inst. for Social Medicine and Epidemiology, Federal Health Office (BGA), Berlin (Germany)); Boegl, K.W. (Laboratory Group, Irradiation of Foods and Pharmaceuticals, Alternative Techniques, Inst. for Social Medicine and Epidemiology, Federal Health Office (BGA), Berlin (Germany)); Schreiber, G.A. (Laboratory Group, Irradiation of Foods and Pharmaceuticals, Alternative Techniques, Inst. for Social Medicine and Epidemiology, Federal Health Office (BGA), Berlin (Germany))

    1993-01-01

    Since sample preparation with HPLC coupled on-line to the GC has been performed for only a few weeks in our laboratory, the results presented give a first look at what can be done by means of this technique. Even difficult samples as the described fish species, where an unequivocal identification regarding an irradiation treatment seemed to become a hopeless enterprise, could be managed. Because of the greater variety of fatty acids in fish ''new'' radiation-induced hydrocarbons were available. According to the theory of Nawar in addition to 16:2 and 17:2 hydrocarbons we have looked for in irradiated meat, further alkadienes appeared in irradiated fish, which were 14:2, 18:2 and 20:2. Analysis of the alkadiene-fraction, transferred to the GC after a two step LC clean up, resulted in an unequivocal identification of all fish samples as well as the fruits and sponge cake. For fruits and sponge cake the detection limit seems to be clearly below 0.5 kGy. It can further be lowered by increasing the amount of lipid whereas the upper limit for a certain LC column has to be determined. In contrast to these samples only qualitative results were obtained for fish. In the case of sponge cake for the first time irradiation of a component of a heat treated food was detected. Further investigations regarding reproducibility, dose dependence and detection limit have to be done. On-line coupled (LC-)LC-GC was proved to be a highly efficient method for analysis of complex samples. In contrast to off-line Florisil column chromatography only a small part of the initial lipid material is needed because the complete hydrocarbon fraction is transferred on-line to the GC. This offers the possibility to analyze even foods with a low fat content like various seafoods. Classification of the hydrocarbon fraction by a two step LC may facilitate the identification of the radiolytic products also if no mass spectrometric detection system is available. (orig./vhe)

  1. Astronomy On-Line Programme Enters "hot Week"

    Science.gov (United States)

    1996-11-01

    World's Biggest Astronomy WWW-Event Attracts Thousands of Students The Astronomy On-line Programme (See ESO Press Release 09/96 of 18 June 1996) began officially on 1 October and is now about to enter its most intense phase, known as the Hot Week . On 18 - 22 November, an estimated 4000 astronomy-interested, mostly young people in Europe and on four other continents will get together during five days in what - not unexpected - has become the world's biggest astronomy event ever organised on the World Wide Web. This carefully structured Programme is carried out in collaboration between the European Association for Astronomy Education (EAAE), the European Southern Observatory and the European Commission, under the auspices of the Fourth European Week for Scientific and Technological Culture. The Programme has already had a most visible impact on the school education of natural sciences in various countries; for instance, the Internet-connection of schools has been advanced in some, in order to allow groups to participate. There have been numerous contacts among the groups across the borders and there are clear signs that many Astronomy On-line participants have progressed to use the impressive possibilities of the Web in an efficient and structured way. There has been a lively media interest in Astronomy On-line all over Europe and it is expected to increase during the next week. The current status of Astronomy On-line It is obvious that the pilot function of the Astronomy On-line Programme in the use of the Web has been very effective and that the associated dissemination of astronomical knowledge has been successful. At this time, more than 650 groups have registered with Astronomy On-line. Most come from 31 different European countries and a few dozen groups are located in North and South America as well as in Asia and Australia. Together they have experienced the steady build-up of Astronomy On-line over the past weeks, by means of numerous contributions from a

  2. On-line beam monitoring for neutron capture therapy at the MIT Research Reactor

    Science.gov (United States)

    Harling, Otto K.; Moulin, Damien J.; Chabeuf, Jean-Michel; Solares, Guido R.

    1995-08-01

    Neutron capture therapy sets new requirements on the measurement and monitoring of the radiation fields used in this new form of therapy. Beams used for neutron capture therapy are comprised of mixed radiation fields which include slow, epithermal, and fast neutrons, as well as gamma rays. A computer-based beam monitoring system for epithermal or thermal neutron capture therapy is described. This system provides accurate, sensitive, and rapid on-line readout and recording of the various beam components. Readout of fluxes, fluences, and corresponding doses in the target are provided in color coded graphic analog as well as numerical form on the computer monitors. Variations in neutron spectrum or spatial distribution of the beam can be rapidly diagnosed with the aid of the monitor readout. Redundancy of fluence measurement is provided by an independent system using scalers and timers and by utilizing reactor power measuring instruments.

  3. A method for analyzing on-line video images of crystallization at high-solid concentrations

    Institute of Scientific and Technical Information of China (English)

    Jian Wan; Cai Y.Ma; Xue Z.Wang

    2008-01-01

    Recent research has demonstrated that on-line video imaging is a very promising technique for monitoring crystallization processes. The bottleneck in applying the technique for real-time closed-loop control is considered as image analysis that needs to be robust, fast and able to handle varied image qualities due to temporal variations of operating conditions such as mixing and solid concentrations. Image analysis at high-solid concentrations turns out to be extremely challenging because crystals tend to overlap or attach to each other and the boundaries between the crystals are usually ambiguous. This paper presents an image segmentation algorithm that can effectively deal with images taken at high-solid concentrations. The method segments crystals attached to each other along the mostly related concave points on the contours of crystal blocks. The detailed procedure is introduced with application to crystallization of L-glutamic acid in a hot-stage reactor.

  4. On-line determination of oxygen isotope ratios of water or ice by mass spectrometry.

    Science.gov (United States)

    Leuenberger, M; Huber, C

    2002-09-15

    Oxygen isotope ratio determination on any of the water phases (water vapor, water, ice) is of great relevance in different research fields such as climate and paleoclimate studies, geological surveys, and hydrological studies. The conventional technique for oxygen isotope measurement involves equilibration with carbon dioxide gas for a given time with a subsequent isotope determination. The equilibration technique is available in different layouts, but all of them are rather time-consuming. Here we report a new on-line technique that processes water samples as well as ice samples. The same principal, CO2 hydration, is used but speeded up by (i) a direct injection and full dissolution of CO2 in the water, (ii) an increased isotope exchange temperature at 50 degrees C, and (iii) a rapid gas extraction by means of an air-permeable membrane into a continuous helium flux supplying the isotope ratio mass spectrometer with the sample gas. The precision is better than 0.1/1000 which is only slightly larger than with the conventional equilibration technique. This on-line technique allows analysis of 1 m of ice with a resolution of 1-3 cm, depending on the meltwater flux, within 1 h. Similarly, continuous and fast analysis can be performed for aqueous samples for hydrological, geological, and perhaps medical applications.

  5. Fast method of the identification of dynamic load location on the beam%梁结构上动载荷位置识别的快速算法

    Institute of Scientific and Technical Information of China (English)

    张景; 张方; 姜金辉; 蒋祺

    2016-01-01

    This paper used a simply supported beam as a study objective ,and set up the finite element model of the beam by PATRAN to obtain the simulating displacement response of the beam .The code was written in MATLAB to identify the location of the dynamic load acting on the beam .This paper proposed a fast method based on the minimum discrimi‐nate coefficient method ,and it identified the the location of the dynamic load by the way of gradually approach .Com‐pared with the common method ,this method cut back the calculation process and time by reduce the division of the finite elements .Simulation showed that this fast method reduced the time of calculation with ensuring the accuracy and exact‐ness of the identification ,which brought convenience to the work of identifying dynamic loads .%将简支梁作为研究对象,通过PATRAN软件建立梁的有限元模型,仿真计算出梁的位移响应,再利用MATLAB编写算法,识别出作用在梁上的动载荷的位置。在最小判别系数法的基础上提出了一种快速算法,该算法通过逐步逼近的方式来识别动载荷的作用位置。与常规方法相比,该快速算法减少了有限单元的划分,所以有效地减少了计算过程并且缩短了计算时间。通过仿真计算,验证了这一快速算法在保证了识别精度和准确性的前提下,缩短了计算时间,为动载荷识别工作带来了便利。

  6. Determination of denaturated proteins and biotoxins by on-line size-exclusion chromatography-digestion-liquid chromatography-electrospray mass spectrometry

    NARCIS (Netherlands)

    Carol, J.; Gorseling, M.C.J.K.; Jong, C.F. de; Lingeman, H.; Kientz, C.E.; Baar, B.L.M. van; Irth, H.

    2005-01-01

    A multidimensional analytical method for the rapid determination and identification of proteins has been developed. The method is based on the size-exclusion fractionation of protein-containing samples, subsequent on-line trypsin digestion and desalination, and reversed-phase high-performance liquid

  7. Determination of denaturated proteins and biotoxins by on-line size-exclusion chromatography-digestion-liquid chromatography-electrospray mass spectrometry

    NARCIS (Netherlands)

    Carol, J.; Gorseling, M.C.J.K.; Jong, C.F. de; Lingeman, H.; Kientz, C.E.; Baar, B.L.M. van; Irth, H.

    2005-01-01

    A multidimensional analytical method for the rapid determination and identification of proteins has been developed. The method is based on the size-exclusion fractionation of protein-containing samples, subsequent on-line trypsin digestion and desalination, and reversed-phase high-performance liquid

  8. On-line Measuring Method for Shell Chamber Volume

    Institute of Scientific and Technical Information of China (English)

    ZHANG Li-zhong; WANG De-min; JIANG Tao; CAO Guo-hua; WANG Qi

    2005-01-01

    Using the ideal gas state equation, an on-line measuring method for the shell chamber volume is studied in this paper. After analyzing how various measurement parameters affect the measurement accuracy, the system parameters are optimized in this method. Because the shape and volume of the tested items are similar, the method of using "tamping" to raise the accuracy and speed of the measurement is put forward. Based on the work above, a prototype of the testing instrument for shell chamber volume was developed, automatically testing and controlling. Compared with the method of "water weight", this method is more accurate, quicker and more automotive, so it is adaptable for the use of on-line detection.

  9. On-line Ramsey Numbers for Paths and Stars

    Directory of Open Access Journals (Sweden)

    Jaroslaw Grytczuk

    2008-08-01

    Full Text Available We study on-line version of size-Ramsey numbers of graphs defined via a game played between Builder and Painter: in one round Builder joins two vertices by an edge and Painter paints it red or blue. The goal of Builder is to force Painter to create a monochromatic copy of a fixed graph H in as few rounds as possible. The minimum number of rounds (assuming both players play perfectly is the on-line Ramsey number r(H of the graph H. We determine exact values of r(H for a few short paths and obtain a general upper bound r(Pn ≤ 4n-7. We also study asymmetric version of this parameter when one of the target graphs is a star Sn with n edges. We prove that r(Sn,H≤n ·e(H when H is any tree, cycle or clique.

  10. On-line corrosion monitoring in district heating systems

    DEFF Research Database (Denmark)

    Richter, Sonja; Thorarinsdottir, R.I.; Hilbert, Lisbeth Rischel

    2004-01-01

    complicates the chemistry of the environment. Hydrogen sulphide is present in geothermal systems and can be formed as a by-product of sulphate-reducing-bacteria (SRB). The application of electrochemical methods makes on-line monitoring possible. These methods include: Linear Polarization Resistance (LPR......), Electrochemical Noise (EN) and Zero Resistance Ammetry (ZRA). Electrochemical Resistance (ER) has also been used to measure corrosion. The method traditionally only measures corrosion off-line but with newly developed high-sensitive ER technique developed by MetriCorr in Denmark, on-line monitoring is possible......Traditionally corrosion monitoring in district heating systems has been performed offline via weight loss coupons. These measurements give information about the past and not the present situation and require long exposure time (weeks or months). The good quality of district heating medium makes...

  11. Fractal groups: Emergent dynamics in on-line learning communities

    Directory of Open Access Journals (Sweden)

    Junia de Carvalho Fidelis Braga

    Full Text Available Drawing on complexity theory, this work discusses the complex dynamics and emergent patterns of on-line learning communities based on a doctoral study in the area of Applied Linguistics. The analysis will center on the interlocutions of fifty students who interacted in small groups without the teacher's direct intervention, in an undergraduate course offered by the School of Languages and Literature at the Federal University of Minas Gerais. By analyzing the data, I demonstrate that out of the interactions among the peers of autonomous on-line learning communities arise opportunities for the construction of shared meaning, distributed leadership, as well as other dynamics. I also demonstrate the fractal nature of these communities. Moreover, I discuss how these findings shed light on the creation and development of course designs for large groups.

  12. On-Line Metrology with Conoscopic Holography: Beyond Triangulation

    Science.gov (United States)

    Álvarez, Ignacio; Enguita, Jose M.; Frade, María; Marina, Jorge; Ojea, Guillermo

    2009-01-01

    On-line non-contact surface inspection with high precision is still an open problem. Laser triangulation techniques are the most common solution for this kind of systems, but there exist fundamental limitations to their applicability when high precisions, long standoffs or large apertures are needed, and when there are difficult operating conditions. Other methods are, in general, not applicable in hostile environments or inadequate for on-line measurement. In this paper we review the latest research in Conoscopic Holography, an interferometric technique that has been applied successfully in this kind of applications, ranging from submicrometric roughness measurements, to long standoff sensors for surface defect detection in steel at high temperatures. PMID:22399984

  13. Escapist Motives for Playing On-Line Games

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    , Harteveld and Mayer’s framework (2009) of escapist motives, which identifies four main motives for playing on-line games: mundane breaking, stress relieving, pleasure seeking, and imagination conjuring. In the paper, we report preliminary findings from an exploratory questionnaire survey. Besides importance...... of escapist motives for playing Facebook and other on-line games, we investigate how they are linked to demographic data such as: age, gender, place of origin, along with other social interactions patterns and social network usage behavior, current gaming status and an estimate of gaming time. According......Social games have become popular along with the tremendous growth of social networking sites, esp. Facebook. There is a gap in literature on what motivates people to play Facebook games. This paper studies social games usage behavior of students. We focus on escapist reasons, based on Warmelink...

  14. Quantifying Cricket Fast Bowling Skill.

    Science.gov (United States)

    Feros, Simon A; Young, Warren B; O'Brien, Brendan J

    2017-09-27

    To evaluate the current evidence regarding the quantification of cricket fast bowling skill. Studies that assessed fast bowling skill (bowling speed and accuracy) were identified from searches in SPORTDiscus (EBSCO) in June 2017. The reference lists of identified papers were also examined for relevant investigations. Sixteen papers matched the inclusion criteria, and discrepancies in assessment procedures were evident. Differences in: test environment, pitch and cricket ball characteristics, the warm-up prior to test, test familiarisation procedures, permitted run-up lengths, bowling spell length, delivery sequence, test instructions, collection of bowling speed data, collection and reportage of bowling accuracy data were apparent throughout the literature. The reliability and sensitivity of fast bowling skill measures has rarely been reported across the literature. Only one study has attempted to assess the construct validity of their skill measures. There are several discrepancies in how fast bowling skill has been assessed and subsequently quantified in the literature to date. This is a problem, as comparisons between studies are often difficult. Therefore, a strong rationale exists for the creation of match-specific standardised fast bowling assessments that offer greater ecological validity while maintaining acceptable reliability and sensitivity of the skill measures. If prospective research can act on the proposed recommendations from this review, then coaches will be able to make more informed decisions surrounding player selection, talent identification, return to skill following injury, and the efficacy of short- and long-term training interventions for fast bowlers.

  15. On-line Corrosion Monitoring in District Heating Systems

    DEFF Research Database (Denmark)

    Richter, Sonja; Thorarinsdottir, R.I.; Hilbert, Lisbeth Rischel

    2005-01-01

    The corrosion control in district heating systems is today performed primarily with control of the water quality. The corrosion rate is kept low by assuring low dissolved oxygen concentration, high pH and low conductivity. Corrosion failures can occur, e.g. as a result of unknown oxygen ingress......, precipitation of deposits or crevices. The authors describe methods used for on-line monitoring of corrosion, cover the complications and the main results of a Nordic project....

  16. On-Line and Back at S.F.U.

    Directory of Open Access Journals (Sweden)

    M. Sanderson

    1973-06-01

    Full Text Available Simon Fraser University library began operation with an automated circulation system. After deliberation, it mounted the first phase of a two-phase online circulation system. A radically revised loan pol·icy caused the system design and assumptions to be called into question. A cheaper, simpler, and more effective off-line system eventually replaced the on-line system. The systems, fiscal, and administrative implications of this decision are reviewed.

  17. Two Types of Designs for On-Line Circulation Systems

    Directory of Open Access Journals (Sweden)

    Rob McGee

    1972-09-01

    Full Text Available On-line circulation systems divide into two types. One type contains records only for charged or otherwise absent items. The other contains a file of records for all titles or volumes in the library collection, regardless of their circulation status. This paper traces differences between the two types, examining different kinds of files and terminals, transaction evidence, the quality of bibliographic data, querying, and the possibility of functions outside circulation. Aspects of both operational and potential systems are considered.

  18. Differential Electronic Nose in On-Line Dynamic Measurements

    Directory of Open Access Journals (Sweden)

    Osowski S.

    2014-12-01

    Full Text Available The paper presents application of differential electronic nose in the dynamic (on-line volatile measurement. First we compare the classical nose employing only one sensor array and its extension in the differential form containing two sensor arrays working in differential mode. We show that differential nose performs better at changing environmental conditions, especially the temperature, and well performs in the dynamic mode of operation. We show its application in recognition of different brands of tobacco

  19. On-line phase space measurement with kicker excitation

    Science.gov (United States)

    Dietrich, J.; Maier, R.; Mohos, I.

    1998-12-01

    A new method for on-line phase space measurements with kicker excitation at COSY was developed. The position data were measured using the analog output of two beam position monitors (BPMs) and directly monitored on a digital storage oscilloscope with an external clock (bunch-synchronous sampling). Nonlinear behavior of the proton beam was visible as well as were resonance islands. Typical measurements are presented.

  20. Not so fast: hippocampal amnesia slows word learning despite successful fast mapping.

    Science.gov (United States)

    Warren, David E; Duff, Melissa C

    2014-08-01

    The human hippocampus is widely believed to be necessary for the rapid acquisition of new declarative relational memories. However, processes supporting on-line inferential word use ("fast mapping") may also exercise a dissociable learning mechanism and permit rapid word learning without the hippocampus (Sharon et al. (2011) Proc Natl Acad Sci USA 108:1146-1151). We investigated fast mapping in severely amnesic patients with hippocampal damage (N = 4), mildly amnesic patients (N = 6), and healthy comparison participants (N = 10) using on-line measures (eye movements) that reflected ongoing processing. All participants studied unique word-picture associations in two encoding conditions. In the explicit-encoding condition, uncommon items were paired with their names (e.g., "This is a numbat."). In the fast mapping study condition, participants heard an instruction using a novel word (e.g., "Click on the numbat.") while two items were presented (an uncommon target such as a numbat, and a common distracter such as a dog). All groups performed fast mapping well at study, and on-line eye movement measures did not reveal group differences. However, while comparison participants showed robust word learning irrespective of encoding condition, severely amnesic patients showed no evidence of learning after fast mapping or explicit encoding on any behavioral or eye-movement measure. Mildly amnesic patients showed some learning, but performance was unaffected by encoding condition. The findings are consistent with the following propositions: the hippocampus is not essential for on-line fast mapping of novel words; but is necessary for the rapid learning of arbitrary relational information irrespective of encoding conditions.

  1. The new on-line Czech Food Composition Database.

    Science.gov (United States)

    Machackova, Marie; Holasova, Marie; Maskova, Eva

    2013-10-01

    The new on-line Czech Food Composition Database (FCDB) was launched on http://www.czfcdb.cz in December 2010 as a main freely available channel for dissemination of Czech food composition data. The application is based on a complied FCDB documented according to the EuroFIR standardised procedure for full value documentation and indexing of foods by the LanguaL™ Thesaurus. A content management system was implemented for administration of the website and performing data export (comma-separated values or EuroFIR XML transport package formats) by a compiler. Reference/s are provided for each published value with linking to available freely accessible on-line sources of data (e.g. full texts, EuroFIR Document Repository, on-line national FCDBs). LanguaL™ codes are displayed within each food record as searchable keywords of the database. A photo (or a photo gallery) is used as a visual descriptor of a food item. The application is searchable on foods, components, food groups, alphabet and a multi-field advanced search. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Review of trigger and on-line processors at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Lankford, A.J.

    1984-07-01

    The role of trigger and on-line processors in reducing data rates to manageable proportions in e/sup +/e/sup -/ physics experiments is defined not by high physics or background rates, but by the large event sizes of the general-purpose detectors employed. The rate of e/sup +/e/sup -/ annihilation is low, and backgrounds are not high; yet the number of physics processes which can be studied is vast and varied. This paper begins by briefly describing the role of trigger processors in the e/sup +/e/sup -/ context. The usual flow of the trigger decision process is illustrated with selected examples of SLAC trigger processing. The features are mentioned of triggering at the SLC and the trigger processing plans of the two SLC detectors: The Mark II and the SLD. The most common on-line processors at SLAC, the BADC, the SLAC Scanner Processor, the SLAC FASTBUS Controller, and the VAX CAMAC Channel, are discussed. Uses of the 168/E, 3081/E, and FASTBUS VAX processors are mentioned. The manner in which these processors are interfaced and the function they serve on line is described. Finally, the accelerator control system for the SLC is outlined. This paper is a survey in nature, and hence, relies heavily upon references to previous publications for detailed description of work mentioned here. 27 references, 9 figures, 1 table.

  3. DEVELOPMENT OF AN ON-LINE COAL WASHABILITY ANALYZER

    Energy Technology Data Exchange (ETDEWEB)

    J.D. Miller; C.L. Lin; G.H. Luttrell; G.T. Adel; Barbara Marin

    2001-06-26

    Washability analysis is the basis for nearly all coal preparation plant separations. Unfortunately, there are no on- line techniques for determining this most fundamental of all coal cleaning information. In light of recent successes at the University of Utah, it now appears possible to determine coal washability on-line through the use of x-ray computed tomography (CT) analysis. The successful development of such a device is critical to the establishment of process control and automated coal blending systems. In this regard, Virginia Tech, Terra Tek Inc., and U.S. coal producers have joined with the University of Utah and to undertake the development of an X-ray CT-based on- line coal washability analyzer with financial assistance from DOE. Each project participant brought special expertise to the project in order to create a new dimension in coal cleaning technology. The project involves development of appropriate software and extensive testing/evaluation of well-characterized coal samples from operating coal preparation plants. Data collected to date suggest that this new technology is capable of serving as a universal analyzer that can not only provide washability analysis, but also particle size distribution analysis, ash analysis, and perhaps pyritic sulfur analysis.

  4. DEVELOPMENT OF AN ON-LINE COAL WASHABILITY ANALYZER

    Energy Technology Data Exchange (ETDEWEB)

    J.D. Miller

    1999-09-30

    Washability analysis is the basis for nearly all coal preparation plant separations. Unfortunately, there are no on-line techniques for determining this most fundamental of all coal cleaning information. In light of recent successes at the University of Utah, it now appears possible to determine coal washability on-line through the use of x-ray computed tomography (CT) analysis. The successful development of such a device is critical to the establishment of process control and automated coal blending systems. In this regard, Virginia Tech, Terra Tek Inc., and several eastern coal companies have joined with the University of Utah and agreed to undertake the development of a x-ray CT-based on-line coal washability analyzer with financial assistance from DOE. The three-year project will cost $594,571, of which 33% ($194,575) will be cost-shared by the participants. The project involves development of appropriate software and extensive testing/evaluation of well-characterized coal samples from operating coal preparation plants. Each project participant brings special expertise to the project which is expected to create a new dimension in coal cleaning technology. Finally, it should be noted that the analyzer may prove to be a universal analyzer capable of providing not only washability analysis, but also particle size distribution analysis, ash analysis and perhaps pyritic sulfur analysis.

  5. Designing effective on-line continuing medical education.

    Science.gov (United States)

    Zimitat, Craig

    2001-03-01

    The Internet, and new information and communication technologies available through the Internet, provides medical educators with an opportunity to develop unique on-line learning environments with real potential to improve physicians' knowledge and effect change in their clinical practice. There are approximately 100 websites offering on-line CME courses in the USA alone. However, few of these CME courses appear to be based on sound educational principles or CME research and may have little chance of achieving the broader goals of CME. The majority of these courses closely resemble their traditional counterparts (e.g. paper-based books are now electronic books) and appear to be mere substitutions for old-technology CME resources. Whilst some CME providers add unique features of the Internet to enrich their websites, they do not employ strategies to optimize the learning opportunities afforded by this new technology. The adoption of adult learning principles, reflective practice and problem-based approaches can be used as a foundation for sound CME course design. In addition, knowledge of Internet technology and the learning opportunities it affords, together with strategies to maintain participation and new assessment paradigms, are all needed for developing online CME. We argue for an evidence-based and strategic approach to the development of on-line CME courses designed to enhance physician learning and facilitate change in clinical behaviour.

  6. A note on on-line Ramsey numbers for quadrilaterals

    Directory of Open Access Journals (Sweden)

    Joanna Cyman

    2014-01-01

    Full Text Available We consider on-line Ramsey numbers defined by a game played between two players, Builder and Painter. In each round Builder draws an the edge and Painter colors it either red or blue, as it appears. Builder's goal is to force Painter to create a monochromatic copy of a fixed graph \\(H\\ in as few rounds as possible. The minimum number of rounds (assuming both players play perfectly is the on-line Ramsey number \\(\\widetilde{r}(H\\ of the graph \\(H\\. An asymmetric version of the on-line Ramsey numbers \\(\\widetilde{r}(G,H\\ is defined accordingly. In 2005, Kurek and Ruciński computed \\(\\widetilde{r}(C_3\\. In this paper, we compute \\(\\widetilde{r}(C_4,C_k\\ for \\(3 \\le k \\le 7\\. Most of the results are based on computer algorithms but we obtain the exact value \\(\\widetilde{r}(C_4\\ and do so without the help of computer algorithms.

  7. Internet Teaching By Style: Profiling the On-line Professor

    Directory of Open Access Journals (Sweden)

    Sharon Strand

    2000-01-01

    Full Text Available The goal of this article is to offer the results of a pilot study which examined the personality type and teaching style preferences of faculty who elected to teach an on-line course. The article will present a description of personality assessments, including the Myers-Briggs Type Indicator (MBTI and Anthony Gregorc's Transaction Ability Inventory used to determine teaching tendencies and styles. In addition, a structured written questionnaire developed by the researchers was used to assess teacher satisfaction with worldwide web-based instruction. Utilizing the results of these psychological assessments, a preliminary analysis of the personal characteristics of college professors who chose to teach on line will be presented. This pilot study found that some preferred teaching styles may be more compatible with the dynamics of distance learning formats. By determining successful teaching styles for on-line courses, we can develop more effective faculty development programs to assist others in successfully transitioning into the cyber-teaching and learning environment.

  8. Differential surface models for tactile perception of shape and on-line tracking of features

    Science.gov (United States)

    Hemami, H.

    1987-01-01

    Tactile perception of shape involves an on-line controller and a shape perceptor. The purpose of the on-line controller is to maintain gliding or rolling contact with the surface, and collect information, or track specific features of the surface such as edges of a certain sharpness. The shape perceptor uses the information to perceive, estimate the parameters of, or recognize the shape. The differential surface model depends on the information collected and on the a priori information known about the robot and its physical parameters. These differential models are certain functionals that are projections of the dynamics of the robot onto the surface gradient or onto the tangent plane. A number of differential properties may be directly measured from present day tactile sensors. Others may have to be indirectly computed from measurements. Others may constitute design objectives for distributed tactile sensors of the future. A parameterization of the surface leads to linear and nonlinear sequential parameter estimation techniques for identification of the surface. Many interesting compromises between measurement and computation are possible.

  9. On-line Detection of Gas Pipeline Based on the Real-Time Algorithm and Network Technology with Robot

    Institute of Scientific and Technical Information of China (English)

    YAN Bo; YAN Guo-zheng; DING Guo-qing; ZHOU Bing; FU Xi-guang; ZUO Jian-yong

    2004-01-01

    The detection system integrates control technology, network technology, video encoding and decoding, video transmiss-ion, multi-single chip microcomputer communication, dat-abase technology, computer software and robot technology. The robot can adaptively adjust its status according to diameter (from 400 mm to 650 mm) of pipeline. The maximum detection distance is up to 1 000 m. The method of video coding in the system is based on fractal transformation. The experiments show that the coding scheme is fast and good PSNR. The precision of on-line detection is up to 3% thickness of pipeline wall. The robot can also have a high precision of location up to 0.03 m. The control method is based on network and characterized by on-line and real-time. The experiment in real gas pipeline shows that the performance of the detection system is good.

  10. On-line monitoring of the transesterification reaction between triglycerides and ethanol using near infrared spectroscopy combined with gas chromatography.

    Science.gov (United States)

    Richard, Romain; Li, Ying; Dubreuil, Brigitte; Thiebaud-Roux, Sophie; Prat, Laurent

    2011-06-01

    Many analytical procedures have been developed to determine the composition of reaction mixtures during transesterification of vegetable oils with alcohols. However, despite their accuracy, these methods are time consuming and cannot be easily used for on-line monitoring. In this work, a fast analytical method was developed to on-line monitor the transesterification reaction of high oleic sunflower oil with ethanol using Near InfraRed spectroscopy and a multivariate approach. The reactions were monitored through sequential scans of the reaction medium with a probe in a one-liter batch reactor without collecting and preparing samples. To calibrate the NIR analytical method, gas chromatography-flame ionization detection was used as a reference method. The method was validated by studying the kinetics of the EtONa-catalyzed transesterification reaction. Activation energy (51.0 kJ/mol) was also determined by considering a pseudo second order kinetics model. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. On-line surface inspection using cylindrical lens-based spectral domain low-coherence interferometry.

    Science.gov (United States)

    Tang, Dawei; Gao, Feng; Jiang, X

    2014-08-20

    We present a spectral domain low-coherence interferometry (SD-LCI) method that is effective for applications in on-line surface inspection because it can obtain a surface profile in a single shot. It has an advantage over existing spectral interferometry techniques by using cylindrical lenses as the objective lenses in a Michelson interferometric configuration to enable the measurement of long profiles. Combined with a modern high-speed CCD camera, general-purpose graphics processing unit, and multicore processors computing technology, fast measurement can be achieved. By translating the tested sample during the measurement procedure, real-time surface inspection was implemented, which is proved by the large-scale 3D surface measurement in this paper. ZEMAX software is used to simulate the SD-LCI system and analyze the alignment errors. Two step height surfaces were measured, and the captured interferograms were analyzed using a fast Fourier transform algorithm. Both 2D profile results and 3D surface maps closely align with the calibrated specifications given by the manufacturer.

  12. On-line detecting of transformer winding deformation based on parameter identification of leakage inductance

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Power transfor mer is an i mportant and expen-sive apparatus in power systems.Usually,trans-for mers operating in power system inevitablyencounter various surging fromshort-circuit fault.The short circuits can directly or indirectly give riseto tremendous electromagnetic stresses and ther malaccumulation,which may further cause the defor m-ation of transfor mer windings,e.g.,variation ofaxial or radial size,windings t wist,knobbing ofwiring harness and turn-to-turn short.Previousstudies on this topic have s...

  13. A Refreshable, On-line Cache for HST Data Retrieval

    Science.gov (United States)

    Fraquelli, Dorothy A.; Ellis, Tracy A.; Ridgaway, Michael; DPAS Team

    2016-01-01

    We discuss upgrades to the HST Data Processing System, with an emphasis on the changes Hubble Space Telescope (HST) Archive users will experience. In particular, data are now held on-line (in a cache) removing the need to reprocess the data every time they are requested from the Archive. OTFR (on the fly reprocessing) has been replaced by a reprocessing system, which runs in the background. Data in the cache are automatically placed in the reprocessing queue when updated calibration reference files are received or when an improved calibration algorithm is installed. Data in the on-line cache are expected to be the most up to date version. These changes were phased in throughout 2015 for all active instruments.The on-line cache was populated instrument by instrument over the course of 2015. As data were placed in the cache, the flag that triggers OTFR was reset so that OTFR no longer runs on these data. "Hybrid" requests to the Archive are handled transparently, with data not yet in the cache provided via OTFR and the remaining data provided from the cache. Users do not need to make separate requests.Users of the MAST Portal will be able to download data from the cache immediately. For data not in the cache, the Portal will send the user to the standard "Retrieval Options Page," allowing the user to direct the Archive to process and deliver the data.The classic MAST Search and Retrieval interface has the same look and feel as previously. Minor changes, unrelated to the cache, have been made to the format of the Retrieval Options Page.

  14. On-line learning algorithms for locally recurrent neural networks.

    Science.gov (United States)

    Campolucci, P; Uncini, A; Piazza, F; Rao, B D

    1999-01-01

    This paper focuses on on-line learning procedures for locally recurrent neural networks with emphasis on multilayer perceptron (MLP) with infinite impulse response (IIR) synapses and its variations which include generalized output and activation feedback multilayer networks (MLN's). We propose a new gradient-based procedure called recursive backpropagation (RBP) whose on-line version, causal recursive backpropagation (CRBP), presents some advantages with respect to the other on-line training methods. The new CRBP algorithm includes as particular cases backpropagation (BP), temporal backpropagation (TBP), backpropagation for sequences (BPS), Back-Tsoi algorithm among others, thereby providing a unifying view on gradient calculation techniques for recurrent networks with local feedback. The only learning method that has been proposed for locally recurrent networks with no architectural restriction is the one by Back and Tsoi. The proposed algorithm has better stability and higher speed of convergence with respect to the Back-Tsoi algorithm, which is supported by the theoretical development and confirmed by simulations. The computational complexity of the CRBP is comparable with that of the Back-Tsoi algorithm, e.g., less that a factor of 1.5 for usual architectures and parameter settings. The superior performance of the new algorithm, however, easily justifies this small increase in computational burden. In addition, the general paradigms of truncated BPTT and RTRL are applied to networks with local feedback and compared with the new CRBP method. The simulations show that CRBP exhibits similar performances and the detailed analysis of complexity reveals that CRBP is much simpler and easier to implement, e.g., CRBP is local in space and in time while RTRL is not local in space.

  15. On-line yields obtained with the ISOLDE RILIS

    Energy Technology Data Exchange (ETDEWEB)

    Koester, U. E-mail: ulli.koster@cern.ch; Fedoseyev, V.N.; Andreyev, A.N.; Bergmann, U.C.; Catherall, R.; Cederkaell, J.; Dietrich, M.; De Witte, H.; Fedorov, D.V.; Fraile, L.; Franchoo, S.; Fynbo, H.; Georg, U.; Giles, T.; Gorska, M.; Hannawald, M.; Huyse, M.; Joinet, A.; Jonsson, O.C.; Kratz, K.L.; Kruglov, K.; Lau, Ch.; Lettry, J.; Mishin, V.I.; Oinonen, M.; Partes, K.; Peraejaervi, K.; Pfeiffer, B.; Ravn, H.L.; Seliverstov, M.D.; Thirolf, P.; Van de Vel, K.; Van Duppen, P.; Van Roosbroeck, J.; Weissman, L

    2003-05-01

    The ISOLDE resonance ionization laser ion source (RILIS) allows to ionize efficiently and selectively many metallic elements. In recent yield surveys and on-line experiments with the ISOLDE RILIS we observed {sup 23-34}Mg, {sup 26-34}Al, {sup 98-132}Cd, {sup 149}Tb, {sup 155-177}Yb, {sup 179-200}Tl, {sup 183-215}Pb and {sup 188-218}Bi. The obtained yields are presented together with measured release parameters which allow to extrapolate the release efficiency towards more exotic (short-lived) nuclides of the same elements.

  16. Integrated sensor array for on-line monitoring micro bioreactors

    NARCIS (Netherlands)

    Krommenhoek, Erik Eduard

    2007-01-01

    In this thesis the development of a microbioreactor array with integrated sensoss suitable for on-line screening of micro organisms is described. Therefore, an array of 2 micro bioreactors compatible with the 96-well microtiterplate format has been made and tested. The developed system was shown to 

  17. TELCAL: The On-line Calibration Software for ALMA

    Science.gov (United States)

    Broguière, D.; Lucas, R.; Pardo, J.; Roche, J.-C.

    2011-07-01

    The ALMA on-line calibration regroups all the operations needed to maintain the ALMA interferometer optimally tuned to successfully execute the planned observations. The results of the calibrations are used in quasi-real time by the ALMA Control System. Since the first ALMA antennas were put into operation in 2009, TELCAL has been used for all the basic calibration operations and is still being improved following the project advancement. We describe here the calibrations done by TELCAL, its relationships with the other ALMA software subsystems and, briefly, the architecture of the software based on CORBA.

  18. Molecularly imprinted polymers for on-line extraction techniques.

    Science.gov (United States)

    Moein, Mohammad M; Abdel-Rehim, Mohamed

    2015-01-01

    Recent years have seen an increasing interest in the use of molecularly imprinted polymers (MIPs) as a sorbent for different extraction methods and this is due to its high selectivity. The MIP is designed to show specificity for the analyte of interest. Moreover, MIPs show physical robustness, resistance to high temperatures and pressures, and stability in the presence of acids, bases and a wide range of organic solvents. In the present article, various novel sample preparation techniques which MIPs applied as sorbent and on-line connected with analytical instruments were highlighted and discussed. The future aspects of MIPs as well were described.

  19. Enhancing Learner Autonomy in an On-line Editing Programme

    Directory of Open Access Journals (Sweden)

    Hebe Wong

    2011-09-01

    Full Text Available Little (1999 argues that in formal educational contexts, “the basis of learner autonomy is acceptance of responsibility for one’s own learning” (p.11. An autonomous learner takes responsibility for various aspects of learning (Benson & Voller, 1997; Holec, 1981. This study examines how learner autonomy opportunities were provided at various stages of writing in an on-line editing programme for a group of electronic engineering students and how the students took charge of their language learning when receiving feedback on their technical writing. The impact on their own learning effectiveness of the decisions students made is also discussed.

  20. On-line Adaptive Radiation Treatment of Prostate Cancer

    Science.gov (United States)

    2008-01-01

    volume (GTV), mandible, rainstem, parotids , and lymph nodes. Another physician repeated he contouring on all planning and on-line images...computed entation. Note the consistency of delineation of gross olume; light blue, nodes; purple, parotid glands; green,k com ostregicomp urs on e...0.9 1.0 Mandible D S C in de x Patient # 1 2 3 4 5 6 7 0.5 0.6 0.7 0.8 0.9 1.0 Left Parotid D S C in de x Patient # Fig. 6. Dice similarity

  1. Adaptive calibration method with on-line growing complexity

    Directory of Open Access Journals (Sweden)

    Šika Z.

    2011-12-01

    Full Text Available This paper describes a modified variant of a kinematical calibration algorithm. In the beginning, a brief review of the calibration algorithm and its simple modification are described. As the described calibration modification uses some ideas used by the Lolimot algorithm, the algorithm is described and explained. Main topic of this paper is a description of a synthesis of the Lolimot-based calibration that leads to an adaptive algorithm with an on-line growing complexity. The paper contains a comparison of simple examples results and a discussion. A note about future research topics is also included.

  2. On-line Measurements of Settling Charateristics in Activated Sludge

    DEFF Research Database (Denmark)

    Rasmussen, Michael R.; Larsen, Torben

    1997-01-01

    An on-line settling column for measuring the dynamic variations of settling velocity of activated sludge has been developed. The settling column is automatic and self-cleansing insuring continuous and reliable measurements. The settling column was tested on sludge from a batch reactor where sucrose...... was added as an impulse to activated sludge. The continuous measurement of settling velocity revealed a highly dynamic response after the sucrose was added. The result were verified with simultaneous measurement of the initial settling rate. A 200 hour experiment showed variations in settling velocity...

  3. Lower Bounds and Semi On-line Multiprocessor Scheduling

    Directory of Open Access Journals (Sweden)

    T.C. Edwin Cheng

    2003-10-01

    Full Text Available We are given a set of identical machines and a sequence of jobs from which we know the sum of the job weights in advance. The jobs have to be assigned on-line to one of the machines and the objective is to minimize the makespan. An algorithm with performance ratio 1.6 and a lower bound of 1.5 is presented. This improves recent results by Azar and Regev who published an algorithm with performance ratio 1.625 for the less general problem that the optimal makespan is known in advance.

  4. On-line Monitoring and Active Control for Transformer Noise

    Science.gov (United States)

    Liang, Jiabi; Zhao, Tong; Tian, Chun; Wang, Xia; He, Zhenhua; Duan, Lunfeng

    This paper introduces the system for on-line monitoring and active noise control towards the transformer noise based on LabVIEW and the hardware equipment including the hardware and software. For the hardware part, it is mainly focused on the composition and the role of hardware devices, as well as the mounting location in the active noise control experiment. And the software part introduces the software flow chats, the measurement and analysis module for the sound pressure level including A, B, C weighting methods, the 1/n octave spectrum and the power spectrum, active noise control module and noise data access module.

  5. Efficient and Secure Comparison for On-Line Auctions

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Krøigaard, Mikkel; Geisler, Martin Joakim

    2007-01-01

    We propose a protocol for secure comparison of integers based on homomorphic encryption. We also propose a homomorphic encryption scheme that can be used in our protocol and makes it more efficient than previous solutions. Our protocol is well-suited for application in on-line auctions, both...... with respect to functionality and performance. It minimizes the amount of information bidders need to send, and for comparison of 16 bit numbers with security based on 1024 bit RSA (executed by two parties), our implementation takes 0.28 seconds including all computation and communication. Using precomputation...

  6. Robust Control Methods for On-Line Statistical Learning

    Directory of Open Access Journals (Sweden)

    Capobianco Enrico

    2001-01-01

    Full Text Available The issue of controlling that data processing in an experiment results not affected by the presence of outliers is relevant for statistical control and learning studies. Learning schemes should thus be tested for their capacity of handling outliers in the observed training set so to achieve reliable estimates with respect to the crucial bias and variance aspects. We describe possible ways of endowing neural networks with statistically robust properties by defining feasible error criteria. It is convenient to cast neural nets in state space representations and apply both Kalman filter and stochastic approximation procedures in order to suggest statistically robustified solutions for on-line learning.

  7. On-line matrix addition for detecting aerosol particles

    Institute of Scientific and Technical Information of China (English)

    ZHOU; Liuzhu; ZHU; Yuan; GUO; Xiaoyong; ZHAO; Wenwu; ZHENG; Haiyang; Gu; Xuejun; FANG; Li; ZHANG; Weijun

    2006-01-01

    Single aerosol particles were measured by matrix-assisted laser desorption/ionization (MALDI) with an aerosol time-of-flight mass spectrometer (ATOFMS). The inlet to the ATOFMS was coupled with an evaporation/condensation flow cell that allowed matrix addition by condensation onto the particles. The coated particles entered the ion source through three-stage differentially pumped capillary inlet and were then ionized by a focused 266 nm Nd:YAG laser. The mass spectra and aerodynamic size of the single particles can be obtained simultaneously. The on-line matrix addition technique makes it possible to identify biological aerosols in real-time.

  8. An optimised multi-baseline approach for on-line MR-temperature monitoring on commodity graphics hardware

    DEFF Research Database (Denmark)

    de Senneville, Baudouin Denis; Noe, Karsten Østergaard; Ries, Mario

    2008-01-01

    Magnetic Resonance Imaging (MRI) can be used for non invasive temperature mapping and is therefore a promising tool to monitor and control interventional therapies based on thermal ablation. The Proton Resonance Frequency shift MRI technique gives an estimate of the temperature by comparing phase....... They have required significant time to compute however, and have not been sufficiently fast for several real-time temperature mapping applications. This paper proposes to use modern graphics cards (GPUs) to assess on-line motion corrected thermal maps. The computation times obtained on the GPU are compared...

  9. System Identification

    NARCIS (Netherlands)

    Keesman, K.J.

    2011-01-01

    Summary System Identification Introduction.- Part I: Data-based Identification.- System Response Methods.- Frequency Response Methods.- Correlation Methods.- Part II: Time-invariant Systems Identification.- Static Systems Identification.- Dynamic Systems Identification.- Part III: Time-varying

  10. Antioxidant activity assays on-line with liquid chromatography

    NARCIS (Netherlands)

    Niederlander, Harm A. G.; van Beek, Teris A.; Bartasiute, Aiste; Koieva, Irina I.

    2008-01-01

    Screening for antioxidants requires simple in vitro model systems to investigate antioxidant activity. High resolution screening (HRS), combining a separation technique like HPLC with fast post-column (bio)chemical detection can rapidly pinpoint active compounds in complex mixtures. In this paper bo

  11. Constructing a maximum utility slate of on-line advertisements

    CERN Document Server

    Keerthi, S Sathiya

    2007-01-01

    We present an algorithm for constructing an optimal slate of sponsored search advertisements which respects the ordering that is the outcome of a generalized second price auction, but which must also accommodate complicating factors such as overall budget constraints. The algorithm is easily fast enough to use on the fly for typical problem sizes, or as a subroutine in an overall optimization.

  12. Research of on-line detection system for power capacitor

    Science.gov (United States)

    Yao, Junda; Qian, Zheng; Yu, Hao; Xia, Jiuyun

    2016-01-01

    The hidden danger exists in the power capacitor of power system due to long-time operation under the environment of high voltage. Thus, it is possible to induce serious fault, and the on-line detection system is urgently required. In this paper, two methods of the on-line detection system are compared in order to realize the better real-time condition detection. The first method is based on the STM microprocessor with an internal 12 bit A/D converter, which converts analog signals which is arrived from the sample circuit into digital signals, and then the FFT algorithm is used to accomplish the measurement of the voltage and current values of the capacitor. The second method is based on the special electric energy metering IC, which can obtain RMS (Root Mean Square) of voltage and current by processing the sampled data of the voltage and current, and store RMS of voltage and current in its certain registers. The operating condition of the capacitor can be obtained after getting the values of voltage and current. By comparing the measuring results of two methods, the second method could achieve a higher measurement accuracy and more simple construction.

  13. Polar On-Line Acquisition Relay and Transmission System (POLARATS)

    Energy Technology Data Exchange (ETDEWEB)

    Yuracko, K.

    2004-07-15

    POLARATS (Polar On-Line Acquisition Relay And Transmission System) is being developed by YAHSGS LLC (YAHSGS) and Oak Ridge National Laboratory (ORNL) to provide remote, unattended monitoring of environmental parameters under harsh environmental conditions. In particular, instrumental design and engineering is oriented towards protection of human health in the Arctic, and with the additional goal of advancing Arctic education and research. POLARATS will obtain and transmit environmental data from hardened monitoring devices deployed in locations important to understanding atmospheric and aquatic pollutant migration as it is biomagnified in Arctic food chains. An Internet- and personal computer (PC)-based educational module will provide real time sensor data, on-line educational content, and will be integrated with workbooks and textbooks for use in middle and high school science programs. The educational elements of POLARATS include an Internet-based educational module that will instruct students in the use of the data and how those data fit into changing Arctic environments and food chains. POLARATS will: (1) Enable students, members of the community, and scientific researchers to monitor local environmental conditions in real time over the Internet; and (2) Provide additional educational benefits through integration with middle- and high-school science curricula. Information will be relayed from POLARATS devices to classrooms and libraries along with custom-designed POLARATS teaching materials that will be integrated into existing curricula to enhance the educational benefits realized from the information obtained.

  14. Increased Cortical Thickness in Professional On-Line Gamers

    Science.gov (United States)

    Hyun, Gi Jung; Shin, Yong Wook; Kim, Bung-Nyun; Cheong, Jae Hoon; Jin, Seong Nam

    2013-01-01

    Objective The bulk of recent studies have tested whether video games change the brain in terms of activity and cortical volume. However, such studies are limited by several factors including cross-sectional comparisons, co-morbidity, and short-term follow-up periods. In the present study, we hypothesized that cognitive flexibility and the volume of brain cortex would be correlated with the career length of on-line pro-gamers. Methods High-resolution magnetic resonance scans were acquired in twenty-three pro-gamers recruited from StarCraft pro-game teams. We measured cortical thickness in each individual using FreeSurfer and the cortical thickness was correlated with the career length and the performance of the pro-gamers. Results Career length was positively correlated with cortical thickness in three brain regions: right superior frontal gyrus, right superior parietal gyrus, and right precentral gyrus. Additionally, increased cortical thickness in the prefrontal cortex was correlated with winning rates of the pro-game league. Increased cortical thickness in the prefrontal and parietal cortices was also associated with higher performance of Wisconsin Card Sorting Test. Conclusion Our results suggest that in individuals without pathologic conditions, regular, long-term playing of on-line games is associated with volume changes in the prefrontal and parietal cortices, which are associated with cognitive flexibility. PMID:24474988

  15. On-line estimation of concentration parameters in fermentation processes

    Institute of Scientific and Technical Information of China (English)

    XIONG Zhi-hua; HUANG Guo-hong; SHAO Hui-he

    2005-01-01

    It has long been thought that bioprocess, with their inherent measurement difficulties and complex dynamics, posed almost insurmountable problems to engineers. A novel software sensor is proposed to make more effective use of those measurements that are already available, which enable improvement in fermentation process control. The proposed method is based on mixtures of Gaussian processes (GP) with expectation maximization (EM) algorithm employed for parameter estimation of mixture of models. The mixture model can alleviate computational complexity of GP and also accord with changes of operating condition in fermentation processes, i.e., it would certainly be able to examine what types of process-knowledge would be most relevant for local models' specific operating points of the process and then combine them into a global one. Demonstrated by on-line estimate of yeast concentration in fermentation industry as an example, it is shown that soft sensor based state estimation is a powerful technique for both enhancing automatic control performance of biological systems and implementing on-line monitoring and optimization.

  16. On-line structure-lossless digital mammogram image compression

    Science.gov (United States)

    Wang, Jun; Huang, H. K.

    1996-04-01

    This paper proposes a novel on-line structure lossless compression method for digital mammograms during the film digitization process. The structure-lossless compression segments the breast and the background, compresses the former with a predictive lossless coding method and discards the latter. This compression scheme is carried out during the film digitization process and no additional time is required for the compression. Digital mammograms are compressed on-the-fly while they are created. During digitization, lines of scanned data are first acquired into a small temporary buffer in the scanner, then they are transferred to a large image buffer in an acquisition computer which is connected to the scanner. The compression process, running concurrently with the digitization process in the acquisition computer, constantly checks the image buffer and compresses any newly arrived data. Since compression is faster than digitization, data compression is completed as soon as digitization is finished. On-line compression during digitization does not increase overall digitizing time. Additionally, it reduces the mammogram image size by a factor of 3 to 9 with no loss of information. This algorithm has been implemented in a film digitizer. Statistics were obtained based on digitizing 46 mammograms at four sampling distances from 50 to 200 microns.

  17. The Leuven isotope separator on-line laser ion source

    CERN Document Server

    Kudryavtsev, Y; Franchoo, S; Huyse, M; Gentens, J; Kruglov, K; Müller, W F; Prasad, N V S; Raabe, R; Reusen, I; Van den Bergh, P; Van Duppen, P; Van Roosbroeck, J; Vermeeren, L; Weissman, L

    2002-01-01

    An element-selective laser ion source has been used to produce beams of exotic radioactive nuclei and to study their decay properties. The operational principle of the ion source is based on selective resonant laser ionization of nuclear reaction products thermalized and neutralized in a noble gas at high pressure. The ion source has been installed at the Leuven Isotope Separator On-Line (LISOL), which is coupled on-line to the cyclotron accelerator at Louvain-la-Neuve. sup 5 sup 4 sup , sup 5 sup 5 Ni and sup 5 sup 4 sup , sup 5 sup 5 Co isotopes were produced in light-ion-induced fusion reactions. Exotic nickel, cobalt and copper nuclei were produced in proton-induced fission of sup 2 sup 3 sup 8 U. The b decay of the sup 6 sup 8 sup - sup 7 sup 4 Ni, sup 6 sup 7 sup - sup 7 sup 0 Co, sup 7 sup 0 sup - sup 7 sup 5 Cu and sup 1 sup 1 sup 0 sup - sup 1 sup 1 sup 4 Rh isotopes has been studied by means of beta-gamma and gamma-gamma spectroscopy. Recently, the laser ion source has been used to produce neutron-d...

  18. Increased cortical thickness in professional on-line gamers.

    Science.gov (United States)

    Hyun, Gi Jung; Shin, Yong Wook; Kim, Bung-Nyun; Cheong, Jae Hoon; Jin, Seong Nam; Han, Doug Hyun

    2013-12-01

    The bulk of recent studies have tested whether video games change the brain in terms of activity and cortical volume. However, such studies are limited by several factors including cross-sectional comparisons, co-morbidity, and short-term follow-up periods. In the present study, we hypothesized that cognitive flexibility and the volume of brain cortex would be correlated with the career length of on-line pro-gamers. High-resolution magnetic resonance scans were acquired in twenty-three pro-gamers recruited from StarCraft pro-game teams. We measured cortical thickness in each individual using FreeSurfer and the cortical thickness was correlated with the career length and the performance of the pro-gamers. CAREER LENGTH WAS POSITIVELY CORRELATED WITH CORTICAL THICKNESS IN THREE BRAIN REGIONS: right superior frontal gyrus, right superior parietal gyrus, and right precentral gyrus. Additionally, increased cortical thickness in the prefrontal cortex was correlated with winning rates of the pro-game league. Increased cortical thickness in the prefrontal and parietal cortices was also associated with higher performance of Wisconsin Card Sorting Test. Our results suggest that in individuals without pathologic conditions, regular, long-term playing of on-line games is associated with volume changes in the prefrontal and parietal cortices, which are associated with cognitive flexibility.

  19. Precise On-line Position Measurement for Particle Therapy

    CERN Document Server

    Actis, O; König, S

    2014-01-01

    An on-line beam position monitoring and regular beam stability tests are of utmost importance for the Quality Assurance (QA) of the patient treatment at any particle therapy facility. The Gantry${0.5 mm}2$ at the Paul Scherrer Institute uses a strip ionization chamber for the on-line beam position verification. The design of the strip chamber placed in the beam in front of the patient allows for a small beam penumbra in order to achieve a high-quality lateral beam delivery. The detector granularity and the low noise allow the reconstruction of the signals offered by Gantry${0.5 mm}2$ with a precision of about 0.1 mm. The frond-end electronics and the whole data processing sequence have been optimized for minimizing the dead time between the beam applications to about 2 ms: the charge collection is performed in about 1 ms, read-out takes place in 100 $\\mu$s while data verification and logging are completed in less than 1 ms. The sub-millimeter precision of the lateral reconstruction allows the dose inhomogenei...

  20. Fully On-line Introductory Physics with a Lab

    Science.gov (United States)

    Schatz, Michael

    We describe the development and implementation of a college-level introductory physics (mechanics) course and laboratory that is suited for both on-campus and on-line environments. The course emphasizes a ``Your World is Your Lab'' approach whereby students first examine and capture on video (using cellphones) motion in their immediate surroundings, and then use free, open-source software both to extract data from the video and to apply physics principles to build models that describe, predict, and visualize the observations. Each student reports findings by creating a video lab report and posting it online; these video lab reports are then distributed to the rest of the class for peer review. In this talk, we will discuss the student and instructor experiences in courses offered to three distinct audiences in different venues: (1) a Massively Open On-line Course (MOOC) for off-campus participants, (2) a flipped/blended course for on-campus students, and, most recently, (3) a fully-online course for off-campus students.

  1. FEDIX on-line information service: Design, develop, test, and implement, an on-line research and education information service

    Energy Technology Data Exchange (ETDEWEB)

    Rodman, J.A.

    1992-01-01

    The FEDIX Annual Status Report provides details regarding an on-line information project designed, developed and implemented by Federal Information Exchange, Inc., a diversified information services company. This document details the project design activities, summarizes the developmental phases of the project and describes the implementation activities generated to fulfill the project's objectives. The information contained in this document illustrates FIE's continuing commitment to serve as the link that facilitates the dissemination of federal information to the education community. This report reviews the project accomplishments and describes intended service enhancements.

  2. FAST: FAST Analysis of Sequences Toolbox.

    Science.gov (United States)

    Lawrence, Travis J; Kauffman, Kyle T; Amrine, Katherine C H; Carper, Dana L; Lee, Raymond S; Becich, Peter J; Canales, Claudia J; Ardell, David H

    2015-01-01

    FAST (FAST Analysis of Sequences Toolbox) provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU's Not Unix) Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R, and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics make FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format). Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought.

  3. FAST: FAST Analysis of Sequences Toolbox

    Directory of Open Access Journals (Sweden)

    Travis J. Lawrence

    2015-05-01

    Full Text Available FAST (FAST Analysis of Sequences Toolbox provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU’s Not Unix Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics makes FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format. Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought.

  4. Configuration Database for BaBar On-line

    Energy Technology Data Exchange (ETDEWEB)

    Salnikov, Andrei

    2003-05-27

    The configuration database is one of the vital systems in the BaBar on-line system. It provides services for the different parts of the data acquisition system and control system, which require run-time parameters. The original design and implementation of the configuration database played a significant role in the successful BaBar operations since the beginning of experiment. Recent additions to the design of the configuration database provide better means for the management of data and add new tools to simplify main configuration tasks. We describe the design of the configuration database, its implementation with the Objectivity/DB object-oriented database, and our experience collected during the years of operation.

  5. On-line corrosion monitoring in district heating systems

    DEFF Research Database (Denmark)

    Richter, Sonja; Thorarinsdottir, R.I.; Hilbert, Lisbeth Rischel

    2004-01-01

    Traditionally corrosion monitoring in district heating systems has been performed offline via weight loss coupons. These measurements give information about the past and not the present situation and require long exposure time (weeks or months). The good quality of district heating medium makes...... corrosion monitoring a challenge. Under normal conditions the pH is high (app. 9), conductivity is low (app. 10-200 µS/cm) and the concentration of dissolved oxygen is negligible. The low corrosion rates (in the order of µm/y) are difficult to measure and furthermore, factors such as hydrogen sulphide......), Electrochemical Noise (EN) and Zero Resistance Ammetry (ZRA). Electrochemical Resistance (ER) has also been used to measure corrosion. The method traditionally only measures corrosion off-line but with newly developed high-sensitive ER technique developed by MetriCorr in Denmark, on-line monitoring is possible...

  6. The Task Manager for the LHCb On-Line Farm

    CERN Document Server

    Bonifazi, F; Carbone, A; Galli, D; Gregori, D; Marconi, U; Peco, G; Vagnoni, V

    2004-01-01

    The Task Manager is a utility to start, stop and list processes on the on-line farm. Each process started by the Task Manager has a string environment variable set, named UTGID (User defined unique Thread Group Identifier) which allows to identify the process. The Task Manager uses the UTGID to list the running processes and to identify the processes to be stopped. It has also the ability to start a process using a particular user name and to set the scheduler type and the priority for the process itself. The Task Manager package includes a Linux DIM server (tmSrv), four Linux command line DIM clients (tmStart, tmLs, tmKill and tmStop) and a JCOP (Joint Control Project) PVSS client.

  7. On-line Test for Train Communication Based System

    Institute of Scientific and Technical Information of China (English)

    Zeng Xiaoqing; Masayuki Matsumoto; Kinji Mori; XU Fucang

    2002-01-01

    This paper gives out a new train automatic control system, which is based on train communication, and proposes a high assurance method to construct the system from current system. In current automatic train control (ATC) system, the central logic device detects position of each train and calculates permissible speed of each blocking section. Therefore, the central logic device controls speed of all trains. On the contrary, in the new system proposed in this paper, there is no central logical device and, train can communicate each other. The train detects the position and calculates the permissible speed itself according to the received position information of the preceding train. In the traditional method of changing an old system to a new one, test must be done off-line.While the integration technique proposed in this paper achieves on-line properties, and high assurance can be satisfied.

  8. An on-line method in studying music parsing.

    Science.gov (United States)

    Berent, I; Perfetti, C A

    1993-03-01

    Listening to music entails the construction of a mental representation based on partial and ambiguous information. This study examines an experimental method that reflects such parsing decisions on-line by detecting the cognitive load resulting from temporary parsing failures. The method investigated was a divided attention paradigm in which listening to music was the primary task and click detection was a concurrent secondary task. It was hypothesized that increasing the complexity of the primary task by introducing an unprepared chromatic modulation results in an increase in response latencies to a click presented immediately after the modulatory shift. The support of this prediction by musicians' data provides evidence for the sensitivity of the paradigm. The failure of non-musicians to reflect the expected load is attributed to their attention-allocation strategy. These results are discussed in terms of their implications on the view of the musical parser as deterministic.

  9. 3rd Computer Science On-line Conference

    CERN Document Server

    Senkerik, Roman; Oplatkova, Zuzana; Silhavy, Petr; Prokopova, Zdenka

    2014-01-01

    This book is based on the research papers presented in the 3rd Computer Science On-line Conference 2014 (CSOC 2014).   The conference is intended to provide an international forum for discussions on the latest high-quality research results in all areas related to Computer Science. The topics addressed are the theoretical aspects and applications of Artificial Intelligences, Computer Science, Informatics and Software Engineering.   The authors provide new approaches and methods to real-world problems, and in particular, exploratory research that describes novel approaches in their field. Particular emphasis is laid on modern trends in selected fields of interest. New algorithms or methods in a variety of fields are also presented.   This book is divided into three sections and covers topics including Artificial Intelligence, Computer Science and Software Engineering. Each section consists of new theoretical contributions and applications which can be used for the further development of knowledge of everybod...

  10. The Monitor System for the LHCb on-line farm

    CERN Document Server

    Bonifazi, F; Carbone, A; Galli, D; Gregori, D; Marconi, U; Peco, G; Vagnoni, V

    2005-01-01

    The aim of the LHCb on-line farm Monitor System is to keep under control all the working indicators which are relevant for the farm operation, and to set the appropriate alarms whenever an error or a critical condition comes up. Since the most stressing tasks of the farm are the data transfer and processing, relevant indicators includes the CPU and the memory load of the system, the network interface and the TCP/IP stack parameters, the rates of the interrupts raised by the network interface card and the detailed status of the running processes. The monitoring of computers’ physical conditions (temperatures, fan speeds and motherboard voltages) are the subject of a separate technical note, since they are accessed in a different way, by using the IPMI protocol.

  11. The Message Logger for the LHCb on-line farm

    CERN Document Server

    Bonifazi, F; Carbone, A; Galli, D; Gregori, D; Marconi, U; Peco, G; Vagnoni, V

    2005-01-01

    The Message Logger is a utility which provide a logger facility for the processes running on the nodes of the on-line farm. It can also be used to collect the processes stdout/stderr. The Message Logger can be exploited using two different policies: either as a no-drop logger facility (messages cannot be lost, but a write to the logger facility blocks in case of full-buffer condition, due e.g. to a network congestion) or as a congestion-proof logger facility (a write to the logger facility never locks even in case of network congestion, but, in this case, messages are dropped). The Message Logger package includes a Linux DIM server (logSrv), a Linux terminal/command-line DIM client (logViewer) and a PVSS DIM client.

  12. On-line blind separation of non-stationary signals

    Directory of Open Access Journals (Sweden)

    Todorović-Zarkula Slavica

    2005-01-01

    Full Text Available This paper addresses the problem of blind separation of non-stationary signals. We introduce an on-line separating algorithm for estimation of independent source signals using the assumption of non-stationary of sources. As a separating model, we apply a self-organizing neural network with lateral connections, and define a contrast function based on correlation of the network outputs. A separating algorithm for adaptation of the network weights is derived using the state-space model of the network dynamics, and the extended Kalman filter. Simulation results obtained in blind separation of artificial and real-world signals from their artificial mixtures have shown that separating algorithm based on the extended Kalman filter outperforms stochastic gradient based algorithm both in convergence speed and estimation accuracy.

  13. A versatile apparatus for on-line emission channeling experiments

    CERN Document Server

    da Silva, Manuel Ribeiro; Correia, João Guilherme; Amorim, Lígia Marina; Pereira, Lino Miguel da Costa

    2013-01-01

    The concept and functionality of an apparatus dedicated to emission channeling experiments using short-lived isotopes on-line at ISOLDE/CERN is described. The setup is assembled in two functional blocks - (a) base stand including beam collimation, implantation and measurement chamber, cryogenic extension, and vacuum control system and - (b) Panmure goniometer extension including maneuvering cradle and sample heating furnace. This setup allows for in situ implantation and sample analysis in the as-implanted state and upon cooling down to 50 K and during annealing up to 1200 K. The functionality of the setup will be illustrated with the example of establishing the lattice location of $^{56}$Mn probes implanted into GaAs.

  14. On-line control of the nonlinear dynamics for synchrotrons

    Science.gov (United States)

    Bengtsson, J.; Martin, I. P. S.; Rowland, J. H.; Bartolini, R.

    2015-07-01

    We propose a simple approach to the on-line control of the nonlinear dynamics in storage rings, based on compensation of the nonlinear resonance driving terms using beam losses as the main indicator of the strength of a resonance. The correction scheme is built on the analysis of the resonance driving terms in first perturbative order and on the possibility of using independent power supplies in the sextupole magnets, which is nowadays present in many synchrotron light sources. Such freedom allows the definition of "smart sextupole knobs" attacking each resonance separately. The compensation scheme has been tested at the Diamond light source and proved to be effective in opening up the betatron tune space, resonance free, available to the electron beam and to improve the beam lifetime.

  15. BCal: an on-line Bayesian radiocarbon calibration tool

    Directory of Open Access Journals (Sweden)

    Caitlin E. Buck

    1999-09-01

    Full Text Available In this paper we describe newly launched software for on-line Bayesian calibration of archaeological radiocarbon determinations. The software is known as BCal and we invite members of the world-wide archaeological research community to use it should they so wish. All that is required to gain access to the software is a computer connected to the Internet with a modern World-wide Web browser (of the sort you are probably using to read this. BCal does not require access to any additional 'Plug-ins' on your machine. Since the computations needed to obtain the calibrations are undertaken on the BCal server, if you have enough computer power to run your World-wide Web browser you have enough power to use BCal.

  16. Parity Codes Used for On-Line Testing in FPGA

    Directory of Open Access Journals (Sweden)

    P. Kubalík

    2005-01-01

    Full Text Available This paper deals with on-line error detection in digital circuits implemented in FPGAs. Error detection codes have been used to ensure the self-checking property. The adopted fault model is discussed. A fault in a given combinational circuit must be detected and signalized at the time of its appearance and before further distribution of errors. Hence safe operation of the designed system is guaranteed. The check bits generator and the checker were added to the original combinational circuit to detect an error during normal circuit operation. This concurrent error detection ensures the Totally Self-Checking property. Combinational circuit benchmarks have been used in this work in order to compute the quality of the proposed codes. The description of the benchmarks is based on equations and tables. All of our experimental results are obtained by XILINX FPGA implementation EDA tools. A possible TSC structure consisting of several TSC blocks is presented. 

  17. On-line non-contact gas analysis

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    Non-intrusive and fast measurements of the gas temperature, NO and other gas concentrations at elevated temperatures in boilers, engines and flames are of the great interest. The optical properties of the gases must be known in a spectral range and temperature level of interest. High-resolution I...... composition in the near-burner field with co-firing of biomass and coal, and NO measurements in a large diesel engine....

  18. Combination Method of Principal Component Analysis and Support Vector Machine for On-line Process Monitoring and Fault Diagnosis

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    On-line monitoring and fault diagnosis of chemical process is extremely important for operation safety and product quality. Principal component analysis (PCA) has been widely used in multivariate statistical process monitoring for its ability to reduce processes dimensions. PCA and other statistical techniques, however, have difficulties in differentiating faults correctly in complex chemical process.Support vector machine (SVM) is a novel approach based on statistical learning theory, which has emerged for feature identification and classification. In this paper, an integrated method is applied for process monitoring and fault diagnosis, which combines PCA for fault feature extraction and multiple SVMs for identification of different fault sources. This approach is verified and illustrated on the Tennessee Eastman benchmark process as a case study.Results show that the proposed PCA-SVMs method has good diagnosis capability and overall diagnosis correctness rate.

  19. On-line (HPLC-NMR) and off-line phytochemical profiling of the Australian plant, Lasiopetalum macrophyllum.

    Science.gov (United States)

    Timmers, Michael; Urban, Sylvia

    2012-05-01

    On-line (HPLC-NMR) and off-line (HPLC, NMR and MS) methodologies were used to profile the constituents present in the crude extract of Lasiopetalum macrophyllum. On-flow and stop-flow HPLC-NMR supported the presence of trans-tiliroside and permitted partial identification of cis-tiliroside and 4'-methoxy-trans-tiliroside. Off-line isolation led to the unequivocal identification of four flavanoid glycosides including a new structural derivative, 4'-methoxycis-tiliroside. This is the first report of flavonoid glycosides occurring in this plant genus. In addition, a number of structure revisions have been proposed for previously reported flavonoid glycosides that were incorrectly assigned.

  20. Determination of anions with an on-line capillary electrophoresis method; Anionien on-line maeaeritys kapillaarielektroforeesilla - MPKT 10

    Energy Technology Data Exchange (ETDEWEB)

    Siren, H.; Saerme, T.; Kotiaho, T.; Hiissa, T.; Savolahti, P.; Komppa, V. [VTT Chemical Technology, Espoo (Finland)

    1998-12-31

    The aim of the study was to set-up an on-line capillary electrophoresis method for determination of anions in process waters of pulp and paper industry with exporting the results to the process control system of the mill. The quantification is important, since it will give information about the possible causes of precipitation. In recent years, the capillary electrophoresis (CE) due to its high separation efficiency has been shown as a method to take into consideration when analyzing chemical species ranging from small inorganic anions to different macromolecules. Many compounds are not easily detected in their native state, why analysis methods must be developed to improve their detection. Especially, small inorganic and organic anions which do not have chromophores are not sensitive enough for direct-UV detection. In such analyses the anions are mostly detected with indirect-UV technique. Capillary electrophoresis instruments are used to analyze samples in off-line, which seldom represent the situation in process. Therefore, on-line instrument technology with autoanalyzing settings will be needed in quality control. The development of a fully automatic capillary electrophoresis system is underway in co-operation with KCL (The Finnish Pulp and Paper Research Institute). In our research, we have first concentrated on the determination of sulphate in waters of paper industry. The method used for detection of sulphate is based on indirect-UV detection with CE, where the background electrolyte (BGE) is an absorbing mixture of secondary amines. The whole procedure for quantification of sulphate is performed within 15 minutes, after which a new sample is analyzed automatically. The only sample pretreatment is filtration, which is necessary before analysis. The concentrations of sulphate in process waters tested were between 300 and 800 ppm. Our tests show that a simultaneous determination of chloride, sulphate, nitrate, nitrite, sulphite, carbonate and oxalate is also

  1. 77 FR 55811 - Manufacturing Extension Partnership Advisory Board On-line Open Meeting

    Science.gov (United States)

    2012-09-11

    ... National Institute of Standards and Technology Manufacturing Extension Partnership Advisory Board On-line... Manufacturing Extension Partnership (MEP) Advisory Board will hold an open, on-line meeting via webcast on... their remote location. Questions regarding the on-line meeting should be sent to the...

  2. Women Physicians Are Early Adopters of On-Line Continuing Medical Education

    Science.gov (United States)

    Harris, John M., Jr.; Novalis-Marine, Cheryl; Harris, Robin B.

    2003-01-01

    Introduction: On-line continuing medical education (CME) provides advantages to physicians and to medical educators. Although practicing physicians increasingly use on-line CME to meet their educational needs, the overall use of on-line CME remains limited. There are few data to describe the physicians who use this new educational medium; yet,…

  3. Clinical application and comparison of rapid and accurate identification of mycobacterium by gene chip microarray and smear acid-fast staining%基因芯片快速分枝杆菌鉴定技术与涂片抗酸染色技术的临床应用比较∗

    Institute of Scientific and Technical Information of China (English)

    侯沪; 李爱敏; 唐曙明

    2015-01-01

    目的:比较基因芯片快速鉴定分枝杆菌与经典涂片抗酸染色镜检技术的临床应用效果,评估两种方法的优劣性。方法2011~2014年间以基因芯片与涂片抗酸染色两种技术对深圳市所有综合性医院临床怀疑有分枝杆菌感染的标本进行检验。χ%Objective To compare the clinical effect of application of gene chip microscopy technique for rapid identification of Mycobacterium and classic smear acid-fast staining,and to assess the advantages and disadvantages of the wo methods.Methods From 201 1 to 2014,gene chip microarray and smear acid fast staining were used to identify the mycobacterium tuberculosis in speci-mens suspicious of the infection from all the general hospitals of Shenzhen city.Chi-square test was used to compare the positive rates of the two methods.Results A total of 2 481 specimens were collected from clinic.With smear acid-fast staining technique, the positive specimens of 1 93 cases werefound and the positive rate was 7.8%.Meanwhile,31 7 positive samples were detected by the technology of gene chip microarray,and the positive rate was 12.8%.The positive rate of Gene chip microarray technology was higher than that of the smear acid fast staining,and there was significant difference between them (P < 0.05 ).The 31 7 positive samples identified by Gene chip microarray,included 263 cases of Mycobacterium tuberculosis,27 cases of Mycobacterium absces-sus,18 cases of Mycobacterium intracellulare,3 cases of Mycobacterium gastric uLcer,3 cases of Mycobacterium avium,1 case of Mycobacterium Gordonae,1 case of Mycobacterium marinum and 1 case of Mycobacterium Kansas.Conclusion The gene chip mi-croarray technology is fast,accurate,and its positive rate is higher than that of smear acid-fast staining technique.Classification and identification of Mycobacterium is very helpful for clinical individualized treatment of anti mycobacterium infection.

  4. Development of on-line laser power monitoring system

    Science.gov (United States)

    Ding, Chien-Fang; Lee, Meng-Shiou; Li, Kuan-Ming

    2016-03-01

    Since the laser was invented, laser has been applied in many fields such as material processing, communication, measurement, biomedical engineering, defense industries and etc. Laser power is an important parameter in laser material processing, i.e. laser cutting, and laser drilling. However, the laser power is easily affected by the environment temperature, we tend to monitor the laser power status, ensuring there is an effective material processing. Besides, the response time of current laser power meters is too long, they cannot measure laser power accurately in a short time. To be more precisely, we can know the status of laser power and help us to achieve an effective material processing at the same time. To monitor the laser power, this study utilize a CMOS (Complementary metal-oxide-semiconductor) camera to develop an on-line laser power monitoring system. The CMOS camera captures images of incident laser beam after it is split and attenuated by beam splitter and neutral density filter. By comparing the average brightness of the beam spots and measurement results from laser power meter, laser power can be estimated. Under continuous measuring mode, the average measuring error is about 3%, and the response time is at least 3.6 second shorter than thermopile power meters; under trigger measuring mode which enables the CMOS camera to synchronize with intermittent laser output, the average measuring error is less than 3%, and the shortest response time is 20 millisecond.

  5. AMADEUS on-line trigger and filtering methods

    Energy Technology Data Exchange (ETDEWEB)

    Neff, M. [Erlangen Centre for Astroparticle Physics (ECAP), Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erwin-Rommel-Strasse 1, D-91058 Erlangen (Germany)], E-mail: max.neff@physik.uni-erlangen.de; Anton, G.; Graf, K.; Hoessl, J.; Katz, U.; Lahmann, R.; Richardt, C. [Erlangen Centre for Astroparticle Physics (ECAP), Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Physikalisches Institut, Erwin-Rommel-Strasse 1, D-91058 Erlangen (Germany)

    2009-06-01

    AMADEUS is a system designed to investigate the method of acoustic particle detection for high energy neutrinos and the acoustic environment in the deep sea as part of the ANTARES neutrino telescope. In this context, six local clusters of six acoustic sensors each were integrated into the ANTARES infrastructure. The first three clusters have been taking data since December 2007 and the second three since the completion of ANTARES in May 2008. In the paper, the methods used for the on-line triggering and filtering of the data acquired with the AMADEUS set-up are described. On-shore, a dedicated computer-cluster is used to control the off-shore DAQ hardware, to process and store the acoustic data arriving from the sensors. On this cluster different data filtering schemes and triggers are implemented. Transient signals are selected by a variable threshold, which is self-adjusting to the changing conditions of the deep sea. For bipolar pulses-the characteristic acoustic signature of a neutrino-a pattern recognition is used based on cross-correlating the output of the sensors with a pre-defined bipolar pulse. To study the characteristics of the ambient noise in the deep sea an amount of unfiltered data is stored in regular intervals.

  6. On-Line Condition Monitoring using Computational Intelligence

    CERN Document Server

    Vilakazi, C B; Mautla, P; Moloto, E

    2007-01-01

    This paper presents bushing condition monitoring frameworks that use multi-layer perceptrons (MLP), radial basis functions (RBF) and support vector machines (SVM) classifiers. The first level of the framework determines if the bushing is faulty or not while the second level determines the type of fault. The diagnostic gases in the bushings are analyzed using the dissolve gas analysis. MLP gives superior performance in terms of accuracy and training time than SVM and RBF. In addition, an on-line bushing condition monitoring approach, which is able to adapt to newly acquired data are introduced. This approach is able to accommodate new classes that are introduced by incoming data and is implemented using an incremental learning algorithm that uses MLP. The testing results improved from 67.5% to 95.8% as new data were introduced and the testing results improved from 60% to 95.3% as new conditions were introduced. On average the confidence value of the framework on its decision was 0.92.

  7. EXPANDING ACADEMIC VOCABULARY WITH AN INTERACTIVE ON-LINE DATABASE

    Directory of Open Access Journals (Sweden)

    Marlise Horst

    2005-05-01

    Full Text Available University students used a set of existing and purpose-built on-line tools for vocabulary learning in an experimental ESL course. The resources included concordance, dictionary, cloze-builder, hypertext, and a database with interactive self-quizzing feature (all freely available at www.lextutor.ca. The vocabulary targeted for learning consisted of (a Coxhead's (2000 Academic Word List, a list of items that occur frequently in university textbooks, and (b unfamiliar words students had met in academic texts and selected for entry into the class database. The suite of tools were designed to foster retention by engaging learners in deep processing, an aspect that is often described as missing in computer exercises for vocabulary learning. Database entries were examined to determine whether context sentences supported word meanings adequately and whether entered words reflected the unavailability of cognates in the various first languages of the participants. Pre- and post-treatment performance on tests of knowledge of words targeted for learning in the course were compared to establish learning gains. Regression analyses investigated connections between use of specific computer tools and gains.

  8. The on-line low temperature nuclear orientation facility NICOLE

    Science.gov (United States)

    Ohtsubo, T.; Roccia, S.; Stone, N. J.; Stone, J. R.; Gaulard, C.; Köster, U.; Nikolov, J.; Simpson, G. S.; Veskovic, M.

    2017-04-01

    We review major experiments and results obtained by the on-line low temperature nuclear orientation method at the NICOLE facility at ISOLDE, CERN since the year 2000 and highlight their general physical impact. This versatile facility, providing a large degree of controlled nuclear polarization, was used for a long-standing study of magnetic moments at shell closures in the region Z = 28, N = 28–50 but also for dedicated studies in the deformed region around A ∼ 180. Another physics program was conducted to test symmetry in the weak sector and constrain weak coupling beyond V–A. Those two programs were supported by careful measurements of the involved solid state physics parameters to attain the full sensitivity of the technique and provide interesting interdisciplinary results. Future plans for this facility include the challenging idea of measuring the beta–gamma–neutron angular distributions from polarized beta delayed neutron emitters, further test of fundamental symmetries and obtaining nuclear structure data used in medical applications. The facility will also continue to contribute to both the nuclear structure and fundamental symmetry test programs.

  9. The Efficiency of the On-line Samplings

    Directory of Open Access Journals (Sweden)

    Ileana Gabriela NICULESCU-ARON

    2006-01-01

    Full Text Available The rapid growth of the technology from the last decades led to the collateral development of many other sciences. One of the most important inventions was the Internet and the web technologies with a tremendous impact on the society. Statistics, as a social science, at its turn in ongoing development has only to gain from that. Lately, the on line sampling technique greatly developed. Each web site of a certain importance includes in various forms of the questionnaires. These vary from a mere question to lengthy ones and are a part of daily life of those who access the World Wide Web. The main question is how feasible are the results derived from these samplings as the main issue is the representativiness. A nonrepresentative sampling is a futile one. It is a more convenient solution to post a question on the web page and to wait for an answer from the page’s visitors? But how representative is this answer for the target audience? The present paper aims to list the on-lone methodology as well as analyze their efficiency through presenting their advantages and drawbacks.

  10. Using on-line altered auditory feedback treating Parkinsonian speech

    Science.gov (United States)

    Wang, Emily; Verhagen, Leo; de Vries, Meinou H.

    2005-09-01

    Patients with advanced Parkinson's disease tend to have dysarthric speech that is hesitant, accelerated, and repetitive, and that is often resistant to behavior speech therapy. In this pilot study, the speech disturbances were treated using on-line altered feedbacks (AF) provided by SpeechEasy (SE), an in-the-ear device registered with the FDA for use in humans to treat chronic stuttering. Eight PD patients participated in the study. All had moderate to severe speech disturbances. In addition, two patients had moderate recurring stuttering at the onset of PD after long remission since adolescence, two had bilateral STN DBS, and two bilateral pallidal DBS. An effective combination of delayed auditory feedback and frequency-altered feedback was selected for each subject and provided via SE worn in one ear. All subjects produced speech samples (structured-monologue and reading) under three conditions: baseline, with SE without, and with feedbacks. The speech samples were randomly presented and rated for speech intelligibility goodness using UPDRS-III item 18 and the speaking rate. The results indicted that SpeechEasy is well tolerated and AF can improve speech intelligibility in spontaneous speech. Further investigational use of this device for treating speech disorders in PD is warranted [Work partially supported by Janus Dev. Group, Inc.].

  11. Chromatographic on-line detection of bioactives in food

    Directory of Open Access Journals (Sweden)

    Remmelt Van der Werf

    2013-08-01

    Full Text Available ABSTRACTFindings were focused on the anti-oxidative activity of numerous fruits and vegetables by means of an on-line HPLC radical scavenging detection method. The reactant used was the ABTS•+ green radical cation. The system has been optimized in terms of reactor design, and chemical reactions kinetics. It has been qualified to classify molecules in order of their increasing activity to scavenge exogenous radicals. It may be used as a powerful high resolution screening tool to investigate the radical scavenging activities of natural plants. Bioassays consisting in cellular in vitro antioxidant assay using pancreatic β-cells have been used to confirm the bioactivity of the selected micronutrients. This study demonstrated that it is possible to screen at the molecular level, the bioactivity of numerous natural samples and to point out the richness of the local biodiversity in terms of natural resource of functional food ingredients usable for their potential benefits for consumer’s health, wellbeing and wellaging.Key words: HPLC radical scavenging detection method, bioactivity of natural samples

  12. Virtual laboratories: Collaborative environments and facilities-on-line

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, C.E. Jr. [Oak Ridge National Lab., TN (United States). I and C Div.; Cavallini, J.S.; Seweryniak, G.R.; Kitchens, T.A.; Hitchcock, D.A.; Scott, M.A.; Welch, L.C. [Dept. of Energy, Germantown, MD (United States). Mathematical Information, and Computational Sciences Div.; Aiken, R.J. [Dept. of Energy, Germantown, MD (United States). Mathematical Information, and Computational Sciences Div.]|[Lawrence Livermore National Lab., CA (United States); Stevens, R.L. [Argonne National Lab., IL (United States). Mathematics and Computer Sciences Div.

    1995-07-01

    The Department of Energy (DOE) has major research laboratories in a number of locations in the US, typically co-located with large research instruments or research facilities valued at tens of millions to even billions of dollars. Present budget exigencies facing the entire nation are felt very deeply at DOE, just as elsewhere. Advances over the last few years in networking and computing technologies make virtual collaborative environments and conduct of experiments over the internetwork structure a possibility. The authors believe that development of these collaborative environments and facilities-on-line could lead to a ``virtual laboratory`` with tremendous potential for decreasing the costs of research and increasing the productivity of their capital investment in research facilities. The majority of these cost savings would be due to increased productivity of their research efforts, better utilization of resources and facilities, and avoiding duplication of expensive facilities. A vision of how this might all fit together and a discussion of the infrastructure necessary to enable these developments is presented.

  13. On line photochemically induced excitation-emission-kinetic four-way data

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez Giron, A.; Duran-Meras, I.; Espinosa-Mansilla, A. [Department of Analytical Chemistry, University of Extremadura, 06071 Badajoz (Spain); Munoz de la Pena, A. [Department of Analytical Chemistry, University of Extremadura, 06071 Badajoz (Spain)], E-mail: arsenio@unex.es; Canada Canada, F. [Department of Analytical Chemistry, University of Extremadura, 06071 Badajoz (Spain); Olivieri, A.C. [Departamento de Quimica Analitica, Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional de Rosario, Instituto de Quimica de Rosario (CONICET), Suipacha 531, S2002LRK Rosario (Argentina)

    2008-08-01

    The determination of folic acid and its two main serum metabolites, 5-methyltetrahydrofolic acid and tetrahydrofolic acid, has been accomplished using four-way data modelled by the third-order multivariate calibration methods unfolded and N-dimensional partial least-squares (U-PLS and N-PLS), in combination with the separate procedure known as residual trilinearization (RTL). The four-way data were acquired by following the photochemical reaction of these compounds by on line irradiation with a UV lamp. The excitation-emission matrices (EEMs) were recorded as a function of the irradiation time, using a fast scanning spectrofluorimeter. The method achieves selectivity from the different rates at which the corresponding photoproducts of the folic acid derivatives are formed and degraded. Several N-dimensional chemometric algorithms were used and the method was applied to the determination of these compounds in serum samples. The best algorithms to perform the multivariate calibration were U-PLS and N-PLS in combination with the separate residual trilinearization procedure, achieving the second-order advantage. The approach allows minimizing or eliminating traditionally time-consuming sample pre-treatments and can facilitate quantifying an analyte in its native environment.

  14. Fast response filter module with plug flow of filtrate for on-line sampling from submerged cultures of filamentous fungi

    NARCIS (Netherlands)

    Poulsen, B.R.; Ruijter, G.J.G.; Panneman, H.; Iversen, J.J.L.; Visser, J.

    2004-01-01

    Automatic and accurate sampling is both convenient and sometimes necessary to obtain detailed information about cell cultures. We developed an autoclavable sampling system in which culture broth was pumped through an ultrafiltration cross-flow module with a novel filtrate collecting principle and a

  15. Electrospray micromixer chip for on-line derivatization and kinetic studies.

    Science.gov (United States)

    Abonnenc, Mélanie; Dayon, Loïc; Perruche, Brice; Lion, Niels; Girault, Hubert H

    2008-05-01

    An electrospray microchip for mass spectrometry comprising an integrated passive mixer to carry out on-chip chemical derivatizations is described. The microchip fabricated using UV-photoablation is composed of two microchannels linked together by a liquid junction. Downstream of this liquid junction, a mixing unit made of parallel oblique grooves is integrated to the microchannel in order to create flow perturbations. Several mixer designs are evaluated. The mixer efficiency is investigated both by fluorescence study and mass spectrometric monitoring of the tagging reaction of cysteinyl peptides with 1,4-benzoquinone. The comparisons with a microchip without a mixing unit and a kinetic model are used to assess the efficiency of the mixer showing tagging kinetics close to that of bulk reactions in an ideally mixed reactor. As an ultimate application, the electrospray micromixer is implemented in a LC-MS workflow. On-line derivatization of albumin tryptic peptides after a reversed-phase separation and counting of their cysteines drastically enhance the protein identification.

  16. The interaction of lexical tone, intonation and semantic context in on-line spoken word recognition: an ERP study on Cantonese Chinese.

    Science.gov (United States)

    Kung, Carmen; Chwilla, Dorothee J; Schriefers, Herbert

    2014-01-01

    In two ERP experiments, we investigate the on-line interplay of lexical tone, intonation and semantic context during spoken word recognition in Cantonese Chinese. Experiment 1 shows that lexical tone and intonation interact immediately. Words with a low lexical tone at the end of questions (with a rising question intonation) lead to a processing conflict. This is reflected in a low accuracy in lexical identification and in a P600 effect compared to the same words at the end of a statement. Experiment 2 shows that a strongly biasing semantic context leads to much better lexical-identification performance for words with a low tone at the end of questions and to a disappearance of the P600 effect. These results support the claim that semantic context plays a major role in disentangling the tonal information from the intonational information, and thus, in resolving the on-line conflict between intonation and tone. However, the ERP data indicate that the introduction of a semantic context does not entirely eliminate on-line processing problems for words at the end of questions. This is revealed by the presence of an N400 effect for words with a low lexical tone and for words with a high-mid lexical tone at the end of questions. The ERP data thus show that, while semantic context helps in the eventual lexical identification, it makes the deviation of the contextually expected lexical tone from the actual acoustic signal more salient. © 2013 Published by Elsevier Ltd.

  17. Worldwide On-line Distance Learning University Astronomy

    Science.gov (United States)

    Eyres, S. P. S.; Hassall, B. J. M.; Butchart, I.; Bromage, G. E.

    2006-08-01

    The University of Central Lancashire operates a suite of distance learning courses in Astronomy, available both on-line and via CD-ROM. The courses are available worldwide, and emphasise flexibility of study. To this end students can study anything from a single module (1/6^th of a full year at degree level) all the way up to an entire degree entirely by distance learning. Study rates vary from one to four modules each year, and students can move on to Level 2 modules (equivalent to second year level in a UK degree) before completing the full set of Level 1 modules. Over 1000 awards have been made to date. The core syllabus is Astronomy and Cosmology at Level 1, alongside skills in literature research, using computers, and basic observing. We also offer a basic history of European astronomy. At Level 2 we look at the astrophysics of the Sun, the stars, and galaxies including the Milky Way. By Level 3 students are expected to engage in a large individual project, and a collaborative investigation with other students, alongside high-level courses in cosmology, relativity, extreme states of matter and the origins of the elements, life and astronomical objects. While many students are retired people looking to exercise their brains, keen amateur amateurs or professionals with disposable incomes, and significant fraction are teachers seeking to improve their subject knowledge or high school students gaining an edge in the UK University entrance competition. Via our involvement with SALT we offer our courses to members of previously disadvantaged communities. This leads to an incredibly diverse and lively student body.

  18. Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

    Science.gov (United States)

    Dark, Paul; Blackwood, Bronagh; Gates, Simon; McAuley, Danny; Perkins, Gavin D; McMullan, Ronan; Wilson, Claire; Graham, Daniel; Timms, Kate; Warhurst, Geoffrey

    2015-01-01

    There is an urgent need to develop diagnostic tests to improve the detection of pathogens causing life-threatening infection (sepsis). SeptiFast is a CE-marked multi-pathogen real-time PCR system capable of detecting DNA sequences of bacteria and fungi present in blood samples within a few hours. We report here a systematic review and meta-analysis of diagnostic accuracy studies of SeptiFast in the setting of suspected sepsis. A comprehensive search strategy was developed to identify studies that compared SeptiFast with blood culture in suspected sepsis. Methodological quality was assessed using QUADAS. Heterogeneity of studies was investigated using a coupled forest plot of sensitivity and specificity and a scatter plot in receiver operator characteristic space. Bivariate model method was used to estimate summary sensitivity and specificity. From 41 phase III diagnostic accuracy studies, summary sensitivity and specificity for SeptiFast compared with blood culture were 0.68 (95 % CI 0.63-0.73) and 0.86 (95 % CI 0.84-0.89) respectively. Study quality was judged to be variable with important deficiencies overall in design and reporting that could impact on derived diagnostic accuracy metrics. SeptiFast appears to have higher specificity than sensitivity, but deficiencies in study quality are likely to render this body of work unreliable. Based on the evidence presented here, it remains difficult to make firm recommendations about the likely clinical utility of SeptiFast in the setting of suspected sepsis.

  19. Signal trend identification with fuzzy methods.

    Energy Technology Data Exchange (ETDEWEB)

    Reifman, J.; Tsoukalas, L. H.; Wang, X.; Wei, T. Y. C.

    1999-08-19

    A fuzzy-logic-based methodology for on-line signal trend identification is introduced. Although signal trend identification is complicated by the presence of noise, fuzzy logic can help capture important features of on-line signals and classify incoming power plant signals into increasing, decreasing and steady-state trend categories. In order to verify the methodology, a code named PROTREN is developed and tested using plant data. The results indicate that the code is capable of detecting transients accurately, identifying trends reliably, and not misinterpreting a steady-state signal as a transient one.

  20. Identifying fast-food restaurants using a central register as a measure of the food environment

    DEFF Research Database (Denmark)

    Toft, Ulla; Erbs-Maibing, Peter; Glümer, Charlotte

    2011-01-01

    To validate the identification and location of fast-food restaurants according to a government list of inspected food stores and restaurants.......To validate the identification and location of fast-food restaurants according to a government list of inspected food stores and restaurants....

  1. Fast Algorithm of Multivariable Generalized Predictive Control

    Institute of Scientific and Technical Information of China (English)

    Jin,Yuanyu; Pang,Zhonghua; Cui,Hong

    2005-01-01

    To avoid the shortcoming of the traditional (previous)generalized predictive control (GPC) algorithms, too large amounts of computation, a fast algorithm of multivariable generalized predictive control is presented in which only the current control actions are computed exactly on line and the rest (the future control actions) are approximately done off line. The algorithm is simple and can be used in the arbitary-dimension input arbitary-dimension output (ADIADO) linear systems. Because it dose not need solving Diophantine equation and reduces the dimension of the inverse matrix, it decreases largely the computational burden. Finally, simulation results show that the presented algorithm is effective and practicable.

  2. Evaluation of Fast-Forward Video Visualization.

    Science.gov (United States)

    Hoferlin, M; Kurzhals, K; Hoferlin, B; Heidemann, G; Weiskopf, D

    2012-12-01

    We evaluate and compare video visualization techniques based on fast-forward. A controlled laboratory user study (n = 24) was conducted to determine the trade-off between support of object identification and motion perception, two properties that have to be considered when choosing a particular fast-forward visualization. We compare four different visualizations: two representing the state-of-the-art and two new variants of visualization introduced in this paper. The two state-of-the-art methods we consider are frame-skipping and temporal blending of successive frames. Our object trail visualization leverages a combination of frame-skipping and temporal blending, whereas predictive trajectory visualization supports motion perception by augmenting the video frames with an arrow that indicates the future object trajectory. Our hypothesis was that each of the state-of-the-art methods satisfies just one of the goals: support of object identification or motion perception. Thus, they represent both ends of the visualization design. The key findings of the evaluation are that object trail visualization supports object identification, whereas predictive trajectory visualization is most useful for motion perception. However, frame-skipping surprisingly exhibits reasonable performance for both tasks. Furthermore, we evaluate the subjective performance of three different playback speed visualizations for adaptive fast-forward, a subdomain of video fast-forward.

  3. HCUP Fast Stats

    Data.gov (United States)

    U.S. Department of Health & Human Services — HCUP Fast Stats provides easy access to the latest HCUP-based statistics for health information topics. HCUP Fast Stats uses visual statistical displays in...

  4. Fast food (image)

    Science.gov (United States)

    Fast foods are quick, reasonably priced, and readily available alternatives to home cooking. While convenient and economical for a busy lifestyle, fast foods are typically high in calories, fat, saturated ...

  5. Fast food tips (image)

    Science.gov (United States)

    ... challenge to eat healthy when going to a fast food place. In general, avoiding items that are deep ... challenge to eat healthy when going to a fast food place. In general, avoiding items that are deep ...

  6. On-line Geoscience Data Resources for Today's Undergraduates

    Science.gov (United States)

    Goodwillie, A. M.; Ryan, W.; Carbotte, S.; Melkonian, A.; Coplan, J.; Arko, R.; O'Hara, S.; Ferrini, V.; Leung, A.; Bonckzowski, J.

    2008-12-01

    Broadening the experience of undergraduates can be achieved by enabling free, unrestricted and convenient access to real scientific data. With funding from the U.S. National Science Foundation, the Marine Geoscience Data System (MGDS) (http://www.marine-geo.org/) serves as the integrated data portal for various NSF-funded projects and provides free public access and preservation to a wide variety of marine and terrestrial data including rock, fluid, biology and sediment samples information, underway geophysical data and multibeam bathymetry, water column and multi-channel seismics data. Users can easily view the locations of cruise tracks, sample and station locations against a backdrop of a multi-resolution global digital elevation model. A Search For Data web page rapidly extracts data holdings from the database and can be filtered on data and device type, field program ID, investigator name, geographical and date bounds. The data access experience is boosted by the MGDS use of standardised OGC-compliant Web Services to support uniform programmatic interfaces. GeoMapApp (http://www.geomapapp.org/), a free MGDS data visualization tool, supports map-based dynamic exploration of a broad suite of geosciences data. Built-in land and marine data sets include tectonic plate boundary compilations, DSDP/ODP core logs, earthquake events, seafloor photos, and submersible dive tracks. Seamless links take users to data held by external partner repositories including PetDB, UNAVCO, IRIS and NGDC. Users can generate custom maps and grids and import their own data sets and grids. A set of short, video-style on-line tutorials familiarises users step- by-step with GeoMapApp functionality (http://www.geomapapp.org/tutorials/). Virtual Ocean (http://www.virtualocean.org/) combines the functionality of GeoMapApp with a 3-D earth browser built using the NASA WorldWind API for a powerful new data resource. MGDS education involvement (http://www.marine-geo.org/, go to Education tab

  7. Is fast food addictive?

    Science.gov (United States)

    Garber, Andrea K; Lustig, Robert H

    2011-09-01

    Studies of food addiction have focused on highly palatable foods. While fast food falls squarely into that category, it has several other attributes that may increase its salience. This review examines whether the nutrients present in fast food, the characteristics of fast food consumers or the presentation and packaging of fast food may encourage substance dependence, as defined by the American Psychiatric Association. The majority of fast food meals are accompanied by a soda, which increases the sugar content 10-fold. Sugar addiction, including tolerance and withdrawal, has been demonstrated in rodents but not humans. Caffeine is a "model" substance of dependence; coffee drinks are driving the recent increase in fast food sales. Limited evidence suggests that the high fat and salt content of fast food may increase addictive potential. Fast food restaurants cluster in poorer neighborhoods and obese adults eat more fast food than those who are normal weight. Obesity is characterized by resistance to insulin, leptin and other hormonal signals that would normally control appetite and limit reward. Neuroimaging studies in obese subjects provide evidence of altered reward and tolerance. Once obese, many individuals meet criteria for psychological dependence. Stress and dieting may sensitize an individual to reward. Finally, fast food advertisements, restaurants and menus all provide environmental cues that may trigger addictive overeating. While the concept of fast food addiction remains to be proven, these findings support the role of fast food as a potentially addictive substance that is most likely to create dependence in vulnerable populations.

  8. Experiments using least square lattice filters for the identification of structural dynamics

    Science.gov (United States)

    Sundararajan, N.; Montgomery, R. C.

    1983-01-01

    An approach for identifying the dynamics of large space structures is applied to a free-free beam. In this approach the system's order is determined on-line, along with mode shapes, using recursive lattice filters which provide a least square estimate of the measurement data. The mode shapes determined are orthonormal in the space of the measurements and, hence, are not the natural modes of the structure. To determine the natural modes of the structure, a method based on the fast Fourier transform is used on the outputs of the lattice filter. These natural modes are used to obtain the modal amplitude time series which provides the input data for an output error parameter identification scheme that identifies the ARMA parameters of the difference equation model of the modes. the approach is applied to both simulated and experimental data.

  9. Ramadan, fasting and pregnancy

    DEFF Research Database (Denmark)

    Ahmed, Urfan Zahoor; Lykke, Jacob Alexander

    2014-01-01

    In Islam, the month of Ramadan is a period of fasting lasting 29 or 30 days. Epidemiological studies among Muslims in Denmark have not been conducted, but studies show, that fasting among pregnant Muslim women is common. Fasting does not increase the risk of growth restriction or preterm delivery......, but there are reports of decreased foetal movements. Furthermore, the fasting may have long-term health consequences for the offspring, especially when they reach their middle age. According to Islam and the interpretation, pregnant and breast-feeding women are allowed to postpone the fasting of the month of Ramadan...

  10. Integrative Physiology of Fasting.

    Science.gov (United States)

    Secor, Stephen M; Carey, Hannah V

    2016-03-15

    Extended bouts of fasting are ingrained in the ecology of many organisms, characterizing aspects of reproduction, development, hibernation, estivation, migration, and infrequent feeding habits. The challenge of long fasting episodes is the need to maintain physiological homeostasis while relying solely on endogenous resources. To meet that challenge, animals utilize an integrated repertoire of behavioral, physiological, and biochemical responses that reduce metabolic rates, maintain tissue structure and function, and thus enhance survival. We have synthesized in this review the integrative physiological, morphological, and biochemical responses, and their stages, that characterize natural fasting bouts. Underlying the capacity to survive extended fasts are behaviors and mechanisms that reduce metabolic expenditure and shift the dependency to lipid utilization. Hormonal regulation and immune capacity are altered by fasting; hormones that trigger digestion, elevate metabolism, and support immune performance become depressed, whereas hormones that enhance the utilization of endogenous substrates are elevated. The negative energy budget that accompanies fasting leads to the loss of body mass as fat stores are depleted and tissues undergo atrophy (i.e., loss of mass). Absolute rates of body mass loss scale allometrically among vertebrates. Tissues and organs vary in the degree of atrophy and downregulation of function, depending on the degree to which they are used during the fast. Fasting affects the population dynamics and activities of the gut microbiota, an interplay that impacts the host's fasting biology. Fasting-induced gene expression programs underlie the broad spectrum of integrated physiological mechanisms responsible for an animal's ability to survive long episodes of natural fasting.

  11. On-line determination of anions in pulp mills by capillary electrophoresis (CE); Tehdasoloissa tapahtuva anionien kapillaarielektroforeettinen on-line maeaeritys ja sen hyoedyntaeminen prosessivalvonnassa - MPKY 02

    Energy Technology Data Exchange (ETDEWEB)

    Kokkonen, R.; Holmberg, M.; Vainikka, V. [Finnish Pulp and Paper Research Institute, Espoo (Finland)

    1998-12-31

    The aim of the study was to set-up a process control system for on-line measurement of certain anions. Typical anions which forms precipitates in pulp and paper mills are oxalate, carbonate and sulphate. Thus it is important to develop a continuous process analyzing system to control concentration levels of this anions. For the preliminary tests of continuous determinations of chloride and sulphate anions in tap water a simple on-line system was build in KCL (The Finnish Pulp and Paper Research Institute) and connected to a capillary electroforesis apparatus. In the preliminary tests a chromate buffer (ph = 7.6) was used. Separation of chloride and sulphate was excellent but the stability of buffer was not good enough and it was usable only for few hours. After experimental studies VTT developed a stable capillary electrophoresis method based on mixed amine buffer and this was selected for an on-line method for determination of anions in process waters of the pulp and paper industry. In the preliminary on-line test (r = 20) repeatabilities of migration times of sulphate and chloride with the chromate buffer were < 5 % (RSD) and peak heights < 15 % (RSD). With the mixed amine buffer repeatabilities were better. The preliminary tests showed that it is possible to connect a capillary electrophoresis system to on-line measurements. For the moment no commercial on-line CE apparatus is available. (orig.)

  12. On-line Scheduling Algorithm for Penicillin Fed-batch Fermentation

    Institute of Scientific and Technical Information of China (English)

    XUE Yao-feng; YUAN Jing-qi

    2005-01-01

    An on-line scheduling algorithm to maximize gross profit of penicillin fed-batch fermentation is proposed. According to the on-line classification method, fed-batch fermentation batches are classified into three categories. Using the scheduling strategy, the optimal termination sequence of batches is obtained. Pseudo on-line simulations for testing the proposed algorithm with the data from industrial scale penicillin fermentation are carried out.

  13. Development of on-line spectrofluorimetric methodology for selenium monitoring in foods and biological fluids using Chrome azurol S quenching.

    Science.gov (United States)

    Santarossa, Débora G; Fernández, Liliana P

    2017-09-01

    A novel, simple and accurate on-line green methodology for Se(IV) monitoring by molecular fluorescence has been developed. Because the analyte does not exhibit fluorescence, the organic dye Chrome azurol S (CAS) has been chosen to allow detection. The effect of metal-quenching on CAS excitation and emission conditions (λex=300nm; λem=407nm) was used as criterion for analyte quantification in presence of sodium cholate bile salt (NaC). The quenching mechanism was explored, and it can be classified as a collisional type with a Stern-Volmer constant value of 3.0×10(7)molL(-1). To improve the sampling rate, minimize the reagent consumption and generated wastes, an on-line configuration was designed. Experimental variables that affect the fluorimetric sensitivity were optimized using uni-variation assays. Under optimal experimental conditions, the limit of detection was 0.27µgL(-1) with a lineal range for Se(IV) concentration from 0.84 to 6.00µgL(-1). The developed methodology is low cost and fast sampling, allowing Se(IV) quantification in the presence of other common ions. Bulbous vegetables and biological samples were successfully analyzed with an average recovery close to 100%. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. FAST User Guide

    Science.gov (United States)

    Walatka, Pamela P.; Clucas, Jean; McCabe, R. Kevin; Plessel, Todd; Potter, R.; Cooper, D. M. (Technical Monitor)

    1994-01-01

    The Flow Analysis Software Toolkit, FAST, is a software environment for visualizing data. FAST is a collection of separate programs (modules) that run simultaneously and allow the user to examine the results of numerical and experimental simulations. The user can load data files, perform calculations on the data, visualize the results of these calculations, construct scenes of 3D graphical objects, and plot, animate and record the scenes. Computational Fluid Dynamics (CFD) visualization is the primary intended use of FAST, but FAST can also assist in the analysis of other types of data. FAST combines the capabilities of such programs as PLOT3D, RIP, SURF, and GAS into one environment with modules that share data. Sharing data between modules eliminates the drudgery of transferring data between programs. All the modules in the FAST environment have a consistent, highly interactive graphical user interface. Most commands are entered by pointing and'clicking. The modular construction of FAST makes it flexible and extensible. The environment can be custom configured and new modules can be developed and added as needed. The following modules have been developed for FAST: VIEWER, FILE IO, CALCULATOR, SURFER, TOPOLOGY, PLOTTER, TITLER, TRACER, ARCGRAPH, GQ, SURFERU, SHOTET, and ISOLEVU. A utility is also included to make the inclusion of user defined modules in the FAST environment easy. The VIEWER module is the central control for the FAST environment. From VIEWER, the user can-change object attributes, interactively position objects in three-dimensional space, define and save scenes, create animations, spawn new FAST modules, add additional view windows, and save and execute command scripts. The FAST User Guide uses text and FAST MAPS (graphical representations of the entire user interface) to guide the user through the use of FAST. Chapters include: Maps, Overview, Tips, Getting Started Tutorial, a separate chapter for each module, file formats, and system

  15. An On-line Assessment System for English-Chinese Translation

    Institute of Scientific and Technical Information of China (English)

    TIAN Yan; LU Ru-zhan; DUAN Jian-yong

    2007-01-01

    On-line assessment of English-Chinese translation is a challenging task as it involves natural language processing. YanFa, an on-line assessment system for English-Chinese translation, is a pilot research project into scoring student's translation on-line. Based on the theory of translation equivalence, an algorithm called "conceptual similarity matching" was developed. YanFa can assess students' translation on-line timely, generate test papers automatically, offer standard versions of translation, and the scores of each sentence to students. The evaluation proves that YanFa is practical compared with the scores given by experts.

  16. On-Line Booking Policies and Competitive Analysis of Medical Examination in Hospital

    Directory of Open Access Journals (Sweden)

    Li Luo

    2014-01-01

    Full Text Available From the on-line point, we consider the hospital’s medical examination appointment problem with hierarchical machines. This approach eliminates the need for both demand forecasts and a risk-neutrality assumption. Due to different unit revenue, uncertain demand, and arrival of patients, we design on-line booking policies for two kinds of different situations from the perspective of on-line policy and competitive analysis. After that, we prove the optimal competitive ratios. Through numerical examples, we compare advantages and disadvantages between on-line policies and traditional policies, finding that there is different superiority for these two policies under different arrival sequences.

  17. ECHMERIT: A new on-line global mercury-chemistry model

    Science.gov (United States)

    Jung, G.; Hedgecock, I. M.; Pirrone, N.

    2009-04-01

    Mercury is a volatile metal, that is of concern because when deposited and transformed to methylmercury accumulates within the food-web. Due to the long lifetime of elemental mercury, which is the dominant fraction of mercury species in the atmosphere, mercury is prone to long-range transport and therefore distributed over the globe, transported and hence deposited even in regions far from anthropogenic emission sources. Mercury is released to the atmosphere from a variety of natural and anthropogenic sources, in elementary and oxidised forms, and as particulate mercury. It is then transported, but also transformed chemically in the gaseous phase, as well as in aqueous phase within cloud and rain droplets. Mercury (particularly its oxidised forms) is removed from the atmosphere though wet and dry deposition processes, a large fraction of deposited mercury is, after chemical or biological reduction, re-emitted to the atmosphere as elementary mercury. To investigate mercury chemistry and transport processes on the global scale, the new, global model ECHMERIT has been developed. ECHMERIT simulates meteorology, transport, deposition, photolysis and chemistry on-line. The general circulation model on which ECHMERIT is based is ECHAM5. Sophisticated chemical modules have been implemented, including gas phase chemistry based on the CBM-Z chemistry mechanism, as well as aqueous phase chemistry, both of which have been adapted to include Hg chemistry and Hg species gas-droplet mass transfer. ECHMERIT uses the fast-J photolysis routine. State-of-the-art procedures simulating wet and dry deposition and emissions were adapted and included in the model as well. An overview of the model structure, development, validation and sensitivity studies is presented.

  18. BOOK REVIEW: ON-LINE EDUCATION: AN EMANCIPATING VISION

    Directory of Open Access Journals (Sweden)

    Reviewed by Dr. Abdullah KUZU

    2006-04-01

    Full Text Available ON-LINE EDUCATION: AN EMANCIPATING VISION Written by Margarita Victoria Gomez Publisher: Cortez Editora ISBN 85-249-1062-3 São Paulo, Brazil, July 2004. Reviewed by Ricardo Romo TORRES Manuel Moreno Castaneda Maria del Sol Orozco Aguirre Universidad de Guadalajara Virtual MEXICO http://www.udgvirtual.udg.mx "On-line Education " is a book that meets the challenge to present itself as an unfinished text. In addition to demanding an active participation of the reader, it requires a predisposition to complete it through an also inconclusive dialogue. Among its goals we can find the search for education networks that remain under constant reconstruction, maintaining the emancipative vision as an imperative for the reconfiguration, as a constituted tissue for the scaffolding of subjects who impress,imagine, think and have a will. The unfinished part is presented in the following paragraph: "Similar to Babel according to Borges, knowledge is the product of a hazard in which fiction is the universe and where, out of fear of its multiple combinations, individual texts constitute an unfinished tale. In this labyrinth-shaped universe, the mirror and the recurrence do not allow finding the way out" page 134. The sense of being of man within a planetary community is framed by the ontological condition of conclusiveness; the requirement of being more, however, as well. This more is guided by the need for dialogue with others in terms of the opening and maintaining an unconcluded dialogue. The idea of a web or network leads to an articulating demand within the context of the category of wholeness. Based on this category, we will be able to present a reticulum of concepts where we can find included the web, subjectivity, identity, experience, mediation and, of course, digital literacy. This reticulum results in a concept of identified education with a condensed arrival point to something that the author defines as 'the pedagogy of virtuality'. The author is

  19. Advantages and Challenges to the Use of On-Line Feedback in CERN’s Accelerators Controls Configuration Management

    CERN Document Server

    Zaharieva, Z; Rolland Lopez De Coca, J; Romero Marin, A

    2014-01-01

    The Controls Configuration Service (CCS) provides the Configuration Management facilities for the Controls System for all CERN accelerators. It complies with Configuration Management standards, tracking the life of configuration items and their relationships by allowing identification and triggering change management processes. Data stored in the CCS is extracted and propagated to the controls hardware for remote configuration. The article will present the ability of the CCS to audit items and verify conformance to specification with the implementation of on-line feedback focusing on Front-End Computers (FEC) configurations. Long-standing problems existed in this area such as discrepancies between the actual state of the FEC and the configuration sent to it at reboot. This resulted in difficult-to-diagnose behaviour and disturbance for the Operations team. The article will discuss the solution architecture (tailored processes and tools), the development and implementation challenges, as well as the advantages...

  20. On line separation of overlapped signals from multi-time photons for the GEM-based detection system

    Science.gov (United States)

    Czarski, T.; Pozniak, K. T.; Chernyshova, M.; Malinowski, K.; Kasprowicz, G.; Kolasinski, P.; Krawczyk, R.; Wojenski, A.; Zabolotny, W.

    2015-09-01

    The Triple Gas Electron Multiplier (T-GEM) is presented as soft X-ray (SXR) energy and position sensitive detector for high-resolution X-ray diagnostics of magnetic confinement fusion plasmas. Multi-channel measurement system and serial data acquisition for X-ray energy and position recognition is described. Fundamental characteristics are presented for two dimensional detector structure. Typical signals of ADC - Analog to Digital Converter are considered for charge value and position estimation. Coinciding signals for high flux radiation cause the problem for cluster charge identification. The amplifier with shaper determines time characteristics and limits the pulses frequency. Separation of coincided signals was introduced and verified for simulation experiments. On line separation of overlapped signals was implemented applying the FPGA technology with relatively simple firmware procedure. Representative results for reconstruction of coinciding signals are demonstrated.

  1. On-line combustion monitoring on dry low NOx industrial gas turbines

    Science.gov (United States)

    Rea, S.; James, S.; Goy, C.; Colechin, M. J. F.

    2003-07-01

    To reduce the NOx emissions levels produced by industrial gas turbines most manufacturers have adopted a lean premixed approach to combustion. Such combustion systems are susceptible to combustion-driven oscillations, and much of the installed modern gas turbines continue to suffer from reduced reliability due to instability-related problems. The market conditions which now exist under the New Electricity Trading Arrangements provide a strong driver for power producers to improve the reliability and availability of their generating units. With respect to low-emission gas turbines, such improvements can best be achieved through a combination of sophisticated monitoring, combustion optimization and, where appropriate, plant modifications to reduce component failure rates. On-line combustion monitoring (OLCM) provides a vital contribution to each of these by providing the operator with increased confidence in the health of the combustion system and also by warning of the onset of combustion component deterioration which could cause significant downstream damage. The OLCM systems installed on Powergen's combined cycle gas turbine plant utilize high-temperature dynamic pressure transducers mounted close to the combustor to enable measurement of the fluctuating pressures experienced within the combustion system. Following overhaul, a reference data set is determined over a range of operating conditions. Real-time averaged frequency spectra are then compared to the reference data set to enable identification of abnormalities. Variations in the signal may occur due to changes in ambient conditions, fuel composition, operating conditions, and the onset of component damage. The systems on Powergen's plant have been used successfully to detect each of the above, examples of which are presented here.

  2. Automatic on-line monitoring of atmospheric volatile organic compounds: gas chromatography-mass spectrometry and gas chromatography-flame ionization detection as complementary systems.

    Science.gov (United States)

    de Blas, Maite; Navazo, Marino; Alonso, Lucio; Durana, Nieves; Iza, Jon

    2011-11-15

    Traditionally air quality networks have been carrying out the continuous, on-line measurement of volatile organic compounds (VOC) in ambient air with GC-FID. In this paper some identification and coelution problems observed while using this technique in long-term measurement campaigns are described. In order to solve these problems a GC-MS was set up and operated simultaneously with a GC-FID for C2-C11 VOCs measurement. There are few on-line, unattended, long term measurements of atmospheric VOCs performed with GC-MS. In this work such a system has been optimized for that purpose, achieving good repeatability, linearity, and detection limits of the order of the GC-FID ones, even smaller in some cases. VOC quantification has been made by using response factors, which is not frequent in on-line GC-MS. That way, the identification and coelution problems detected in the GC-FID, which may led to reporting erroneous data, could be corrected. The combination of GC-FID and GC-MS as complementary techniques for the measurement of speciated VOCs in ambient air at sub-ppbv levels is proposed. Some results of the measurements are presented, including concentration values for some compounds not found until now on public ambient air VOC databases, which were identified and quantified combining both techniques. Results may also help to correct previously published VOC data with wrongly identified compounds by reprocessing raw chromatographic data.

  3. Automatic on-line monitoring of atmospheric volatile organic compounds: Gas chromatography-mass spectrometry and gas chromatography-flame ionization detection as complementary systems

    Energy Technology Data Exchange (ETDEWEB)

    Blas, Maite de, E-mail: maite.deblas@ehu.es [Chemical and Environmental Engineering Department, University College of Technical Mining and Civil Engineering, University of the Basque Country, Colina de Beurco s/n, 48902 Barakaldo (Spain); Navazo, Marino; Alonso, Lucio; Durana, Nieves [Chemical and Environmental Engineering Department, School of Engineering, University of the Basque Country, Alameda de Urquijo s/n, 48013 Bilbao (Spain); Iza, Jon [Chemical and Environmental Engineering Department, Faculty of Pharmacy, University of the Basque Country, Paseo de la Universidad, 7, 01006, Vitoria-Gasteiz (Spain)

    2011-11-15

    Traditionally air quality networks have been carrying out the continuous, on-line measurement of volatile organic compounds (VOC) in ambient air with GC-FID. In this paper some identification and coelution problems observed while using this technique in long-term measurement campaigns are described. In order to solve these problems a GC-MS was set up and operated simultaneously with a GC-FID for C{sub 2}-C{sub 11} VOCs measurement. There are few on-line, unattended, long term measurements of atmospheric VOCs performed with GC-MS. In this work such a system has been optimized for that purpose, achieving good repeatability, linearity, and detection limits of the order of the GC-FID ones, even smaller in some cases. VOC quantification has been made by using response factors, which is not frequent in on-line GC-MS. That way, the identification and coelution problems detected in the GC-FID, which may led to reporting erroneous data, could be corrected. The combination of GC-FID and GC-MS as complementary techniques for the measurement of speciated VOCs in ambient air at sub-ppbv levels is proposed. Some results of the measurements are presented, including concentration values for some compounds not found until now on public ambient air VOC databases, which were identified and quantified combining both techniques. Results may also help to correct previously published VOC data with wrongly identified compounds by reprocessing raw chromatographic data.

  4. Printed Identification Key or Web-Based Identification Guide: An Effective Tool for Species Identification?

    OpenAIRE

    Thomas Edison E. dela Cruz; Pangilinan, Ma. Victoria B.; Rodrigo A. Litao

    2012-01-01

    Species identification is often done with the aid of traditional dichotomous keys. This printed material is based on one’s decision between two alternatives, which is followed by another pair of alternatives until the final species name is reached. With the advent of internet technology, the use of an online database offers an updatable and accumulative approach to species identification. It can also be accessed anytime, and this is very useful for fast-changing groups of organisms. In this p...

  5. Determination of lycopene in food by on-line SFE coupled to HPLC using a single monolithic column for trapping and separation.

    Science.gov (United States)

    Pól, Jaroslav; Hyötylänen, Tuulia; Ranta-Aho, Outi; Riekkola, Marja-Liisa

    2004-10-15

    A method that would eliminate the degradation of lycopene during analysis was developed. Supercritical fluid extraction (SFE) with carbon dioxide as the extraction medium was connected on-line to high performance liquid chromatography (HPLC) where a single monolithic column was used for trapping and the subsequent separation of analytes. The method was linear over the studied range (0.1-2.5 microg), and it was repeatable (R.S.D. 3.9%), sensitive (LOD = 0.5 ng) and fast (35 min). Lycopene was determined in tomatoes, fruit and several food products. Because of the on-line construction, lycopene was not in contact with air or light during the whole procedure and the amount analysed should therefore correspond to the real amount in the sample.

  6. On-line comprehensive two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography for preparative isolation of toad venom.

    Science.gov (United States)

    Li, Jia-Fu; Fang, Hua; Yan, Xia; Chang, Fang-Rong; Wu, Zhen; Wu, Yun-Long; Qiu, Ying-Kun

    2016-07-22

    An on-line comprehensive preparative two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography (2D NPLC×RPLC) system was constructed with a newly developed vacuum evaporation assisted adsorption (VEAA) interface, allowing fast removal of NPLC solvent in the vacuum condition and successfully solving the solvent incompatibility problem between NPLC and RPLC. The system achieved on-line solvent exchange within the two dimensions and its performance was illustrated by gram-scale isolation of crude extract from the venom of Bufo bufo gargarizans. Within separation time of ∼20h, 19 compounds were obtained with high purity in a single run. With the VEAA interface, the 2D system exhibited apparent advantages in separation efficiency and automation compared with conventional methods, indicating its promising application in the routine separation process for complicated natural products.

  7. A experiência de aprendizagem on-line em um curso de qualificação profissional em saúde The on-line learning experience in a course on professional qualification in health

    Directory of Open Access Journals (Sweden)

    Josué Laguardia

    2010-06-01

    Full Text Available Este artigo analisa as percepções a atitudes dos tutores e alunos nos processos de aprendizagem em um curso de atualização profissional on-line. Para tal realizaram-se entrevistas com dez alunos e três tutores desse curso mediante a utilização de roteiros semiestruturados que abrangiam os seguintes aspectos: ingresso no curso, tecnologias, conteúdos, atividades de avaliação, tutoria; mediação e expectativas quanto ao curso. Os roteiros foram organizados em tópicos que possibilitassem identificar as condições estruturais para o uso das ferramentas disponíveis no ambiente virtual, os tipos de interação, apreensão de conteúdos, bem como as expectativas dos participantes com relação aos objetivos propostos pelo curso. Os relatos dos entrevistados apontam questões importantes a serem consideradas na concepção e gestão de cursos on-line, tais como a necessidade de readequação periódica da proposta pedagógica do curso para atender as demandas dos alunos e tutores quanto à organização e atualização dos conteúdos, os meios de acesso ao material e a implementação de atividades avaliativas compatíveis com a experiência de trabalho.This article examines the perceptions regarding tutor and student attitudes in the learning processes during an on-line professional refresher course. In the study, interviews were carried out among ten students and three tutors of the course by means of semi-structured roadmaps that covered the following aspects: admission to the course, technologies, content, assessment activities, mentoring, mediation, and expectations about the course. The roadmaps were organized into topics that would enable the identification of the structural conditions for the use of the tools that were available in the virtual environment, the types of interaction, the understanding of the content, as well as participants' expectations with respect to the objectives proposed by the course. The interviewees' reports

  8. A novel, optical, on-line bacteria sensor for monitoring drinking water quality

    DEFF Research Database (Denmark)

    Højris, Bo; Christensen, Sarah Christine Boesgaard; Albrechtsen, Hans-Jørgen;

    2016-01-01

    Today, microbial drinking water quality is monitored through either time-consuming laboratory methods or indirect on-line measurements. Results are thus either delayed or insufficient to support proactive action. A novel, optical, on-line bacteria sensor with a 10-minute time resolution has been...... conditions such as pollution events in drinking water....

  9. Analyze On-line Star Economy Basing on Models of Entrepreneurship

    Institute of Scientific and Technical Information of China (English)

    胡志豪

    2016-01-01

    The outstanding performance of the On-line Star Economy is bound up with social media and promotion by fans, stimulating a new round of consumption upgrading and capital tendency. There is no denying that the On-line Star Economy may be the fortuitous outcome of the times. But the fact remains it can be analyzed rationally using Models of Entrepreneurship.

  10. On-line monitoring and control of animal-cell cultures

    NARCIS (Netherlands)

    Pol, van der J.J.

    1996-01-01


    On-line analysis and control of biotechnological processes is still the stepchild in industry. In general, only parameters as dissolved-oxygen concentration, pH and temperature are controlled on-line. Important parameters as substrate and inhibitor concentrations are only measured

  11. On-Line Multichannel Raman Spectroscopic Detection System For Capillary Zone Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    An on-line multichannel Raman spectroscopic detection system for capillary electrophoresis was established by using an Ar+ laser and a cryogenically cooled ICCD. Resonant excitation Raman spectra of methyl red and methyl orange were employed to test the system. The result shows that it could yield on-line electrophoretogram and time series of Raman spectra.

  12. High School Open On-Line Courses (HOOC): A Case Study from Italy

    Science.gov (United States)

    Canessa, Enrique; Pisani, Armando

    2013-01-01

    The first implementation of complete high school, open on-line courses (HOOC) aiming to support the training and basic scientific knowledge of young students from the Liceo Ginnasio Dante Alighieri in Gorizia, Italy, is discussed. Using the open source and automated recording system openEyA, HOOC give a student the opportunity to watch on-line, at…

  13. Challenges and opportunities in ‘last mile’ logistics for on-line food retail

    NARCIS (Netherlands)

    Trienekens, Jacques; Hvolby, Hans Henrik; Turner, Paul

    2017-01-01

    Conventional approaches to logistics for food retail continue to be challenged by the rapid growth of on-line food retail. At the same time, ‘last mile’ logistics optimization for on-line retail also face challenges as changing consumer expectations, habits and purchasing patterns intersect with

  14. The Anatomy of Program Design for an On-Line Business Management Course

    Science.gov (United States)

    Barger, Bonita

    2008-01-01

    How does one design an on-line course to bridge theory and practice? How can the feedback of on-going stakeholder (student and administration) be incorporated into the design process to enhance quality? This paper presents the theoretical underpinning of designing an on-line management course recognized as best practice for a "well organized…

  15. Secure surface identification codes

    Science.gov (United States)

    Beekhof, F.; Voloshynovskiy, S.; Koval, O.; Villan, R.; Pun, T.

    2008-02-01

    This paper introduces an identification framework for random microstructures of material surfaces. These microstructures represent a kind of unique fingerprints that can be used to track and trace an item as well as for anti-counterfeiting. We first consider the architecture for mobile phone-based item identification and then introduce a practical identification algorithm enabling fast searching in large databases. The proposed algorithm is based on reference list decoding. The link to digital communications and robust perceptual hashing is shown. We consider a practical construction of reference list decoding, which comprizes computational complexity, security, memory storage and performance requirements. The efficiency of the proposed algorithm is demonstrated on experimental data obtained from natural paper surfaces.

  16. Improvement plans for the RHIC/AGS on-line model environments

    Energy Technology Data Exchange (ETDEWEB)

    Brown,K.A.; Ahrens, L.; Beebe-Wang, J.; Morris, J.; Nemesure, S.; Robert-Demolaize, G.; Satogata, T.; Schoefer, V.; Tepikian, S.

    2009-08-31

    The on-line models for Relativistic Ion Collider (RHIC) and the RHIC pre-injectors (the AGS and the AGS Booster) can be thought of as containing our best collective knowledge of these accelerators. As we improve these on-line models we are building the framework to have a sophisticated model-based controls system. Currently the RHIC on-line model is an integral part of the controls system, providing the interface for tune control, chromaticity control, and non-linear chromaticity control. What we discuss in this paper is our vision of the future of the on-line model environment for RHIC and the RHIC preinjectors. Although these on-line models are primarily used as Courant-Snyder parameter calculators using live machine settings, we envision expanding these environments to encompass many other problem domains.

  17. A new approach to study fast pyrolysis of pulverized coal

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.; Yao, J.; Lin, W. [Chinese Academy of Sciences, Institute of Chemical Metallurgy Fast Reactions Laboratory, Beijing, BJ (China)

    2002-07-01

    An experimental study of the effects of varying bed temperature and coal particle size on the fast pyrolysis of pulverized coal in a downer reactor is described. A Datong bituminous coal (particle size 0.5 and 0.34 mm) was studied at temperatures ranging from 592{sup o} C to 720{sup o} C. The experiments were conducted in a batch apparatus. An on-line gas analyzer was used to measure carbon dioxide release curves. The experimental data were used to develop a pyrolysis model that quantifies the fast heating of fine coal particles. 14 refs., 4 figs., 2 tabs.

  18. FEDIX on-line information service: Design, develop, test, and implement an on-line research and education information service. Annual status report, September 1992--August 1993

    Energy Technology Data Exchange (ETDEWEB)

    Rodman, J.A.

    1993-08-01

    Federal Information Exchange, Inc. (FIE) is a diversified information services company that is recognized as the major electronic link between the higher education community and the Federal government in the field of research administration. FIE provides a range of information related services to the government, academic and private sectors, including database management, software development and technical support. FEDIX is the on-line information service designed, developed and implemented by FIE to accomplish the following objectives: (1). Broaden the participation of the education community in Federal research and education programs by providing free and unrestricted on-line access to information from all participating Federal agencies; and (2). Provide the education community with on-line access to a single keyword-searchable system for research and educational funding opportunities at the participating Federal agencies.

  19. 尿道及其他显色培养基快速分离鉴定常见泌尿道感染致病菌的临床应用%Urethra and other chromogenic medium fast isolation and identification of common urinary tract infection pathogens in clinical application

    Institute of Scientific and Technical Information of China (English)

    翁杏华; 徐涛; 陈瑞湖; 关尚; 陈玉莲

    2014-01-01

    Objective Urethra and other chromogenic medium fast identification of common urinary tract pathogens isolated in order to avoid errors caused by mixed bacteria identification and susceptibility results. Methods Accordance with the "national clinical laboratory Procedures"3rd edition urine culture methods used;specimens inoculated directly on blood agar and urethra chromogenic media for culture and identification plates,etc. with the French bioMérieux atbexpression automatic identification system for identification of bacteria and / or verification. Results Major urinary tract infection escherichia coli bacteria 49. 1%,klebsiella pneumoniae 8. 9%,proteus 10. 8%. Conclu-sion Proven compliance rate of 90% to 100%. Urethral chromogenic medium can quickly and easily isolated and identified common urina-ry tract pathogens,saving the cost of reagents,suitable for all basic hospital application.%目的:总结尿道及其他显色培养基快速分离鉴定常见泌尿道致病菌以避免混合菌引起错误的鉴定及药敏结果。方法:按照《全国临床检验操作规程》第3版尿培养的方法;标本直接接种在血平板及尿道显色培养基等平板上进行培养鉴定,用法国生物梅里埃公司ATBExpression自动细菌鉴定仪进行鉴定和/或验证。结果:主要泌尿道感染菌49.1%为大肠埃希菌,8.9%为肺炎克雷伯菌,10.8%为变形杆菌。结论:经验证明总符合率为96%,尿道显色培养基能快速、方便分离鉴定常见泌尿道致病菌,节约试剂成本,适合各基层医院推广应用。

  20. Fast growth in control

    NARCIS (Netherlands)

    Z. Rico (Zulay)

    2009-01-01

    textabstractThe focus of this paper is on the influence of the fast growth of organizations on the design process of management control systems. What are the management accounting and control problems that a fast growth organization encounters that can be ascribed to this growth. What are the circum

  1. Fast protein folding kinetics

    Science.gov (United States)

    Gelman, Hannah; Gruebele, Martin

    2014-01-01

    Fast folding proteins have been a major focus of computational and experimental study because they are accessible to both techniques: they are small and fast enough to be reasonably simulated with current computational power, but have dynamics slow enough to be observed with specially developed experimental techniques. This coupled study of fast folding proteins has provided insight into the mechanisms which allow some proteins to find their native conformation well less than 1 ms and has uncovered examples of theoretically predicted phenomena such as downhill folding. The study of fast folders also informs our understanding of even “slow” folding processes: fast folders are small, relatively simple protein domains and the principles that govern their folding also govern the folding of more complex systems. This review summarizes the major theoretical and experimental techniques used to study fast folding proteins and provides an overview of the major findings of fast folding research. Finally, we examine the themes that have emerged from studying fast folders and briefly summarize their application to protein folding in general as well as some work that is left to do. PMID:24641816

  2. Ramadan, faste og graviditet

    DEFF Research Database (Denmark)

    Ahmed, Urfan Zahoor; Lykke, Jacob Alexander

    2014-01-01

    , but there are reports of decreased foetal movements. Furthermore, the fasting may have long-term health consequences for the offspring, especially when they reach their middle age. According to Islam and the interpretation, pregnant and breast-feeding women are allowed to postpone the fasting of the month of Ramadan...

  3. Fast protein folding kinetics.

    Science.gov (United States)

    Gelman, Hannah; Gruebele, Martin

    2014-05-01

    Fast-folding proteins have been a major focus of computational and experimental study because they are accessible to both techniques: they are small and fast enough to be reasonably simulated with current computational power, but have dynamics slow enough to be observed with specially developed experimental techniques. This coupled study of fast-folding proteins has provided insight into the mechanisms, which allow some proteins to find their native conformation well fast folders also informs our understanding of even 'slow' folding processes: fast folders are small; relatively simple protein domains and the principles that govern their folding also govern the folding of more complex systems. This review summarizes the major theoretical and experimental techniques used to study fast-folding proteins and provides an overview of the major findings of fast-folding research. Finally, we examine the themes that have emerged from studying fast folders and briefly summarize their application to protein folding in general, as well as some work that is left to do.

  4. Fast ejendom III

    DEFF Research Database (Denmark)

    Munk-Hansen, Carsten

    Bogen er det tredje bind af tre planlagte bind om fast ejendom: I Overdragelsen, II Bolighandlen og III Ejerbeføjelsen. Fremstillingens giver et grundigt overblik over centrale områder af en omfattende regulering af fast ejendom, med angivelse af litteratur, hvor læseren kan søge yderligere...... oplysning. En ejer af fast ejendom er på særdeles mange områder begrænset i sin råden sammenlignet med ejeren af et formuegode i almindelighed. Fremstillingen tager udgangspunkt i ejerens perspektiv (fremfor samfundets eller myndighedernes). Både den privatretlige og offentligretlige regulering behandles......, eksempelvis ejendomsdannelsen, servitutter, naboretten, hævd, zoneinddelingen, den fysiske planlægning, beskyttelse af natur, beskyttelse af kultur, forurening fra fast ejendom, erstatning for forurening, jordforurening, ekspropriation, byggeri og adgang til fast ejendom....

  5. Islamic Fasting and Diabetes

    Directory of Open Access Journals (Sweden)

    Fereidoun Azizi

    2013-07-01

    Full Text Available The aim of this article is to review health-related aspects of Ramadan fasting in normal individuals and diabetics. During fasting days of Ramadan, glucose homeostasis is maintained by meal taken bepore dawn and by liver glycogen stores. Changes in serum lipids are variable and defend on the quality and quantity of food consumption and changes in weight. Compliant, well controlled type 2 diabetics may observe Ramadan fasting; but fasting is not recommended for type 1, non complaint, poorly controlled and pregnant diabetics. Although Ramadan fasting is safe for all healthy individuals and well controlled diabetics, those with uncontrolled diabetics and diabetics with complications should consult physicians and follow scientific recommendations.

  6. Fast Spectrum Reactors

    CERN Document Server

    Todd, Donald; Tsvetkov, Pavel

    2012-01-01

    Fast Spectrum Reactors presents a detailed overview of world-wide technology contributing to the development of fast spectrum reactors. With a unique focus on the capabilities of fast spectrum reactors to address nuclear waste transmutation issues, in addition to the well-known capabilities of breeding new fuel, this volume describes how fast spectrum reactors contribute to the wide application of nuclear power systems to serve the global nuclear renaissance while minimizing nuclear proliferation concerns. Readers will find an introduction to the sustainable development of nuclear energy and the role of fast reactors, in addition to an economic analysis of nuclear reactors. A section devoted to neutronics offers the current trends in nuclear design, such as performance parameters and the optimization of advanced power systems. The latest findings on fuel management, partitioning and transmutation include the physics, efficiency and strategies of transmutation, homogeneous and heterogeneous recycling, in addit...

  7. El aprendizaje on-line: oportunidades y retos en instituciones politécnicas Apprenticeship Students Learning On-line: Opportunities and Challenges for Polytechnic Institutions

    Directory of Open Access Journals (Sweden)

    Martha Burkle

    2011-10-01

    Full Text Available Este artículo presenta los retos y las oportunidades actuales respecto a la distribución de contenidos virtuales y online en el marco de la institución de educación superior politécnica. Debido a la recesión económica actual, se está produciendo un retorno de estudiantes aprendices al mundo académico con el fin de actualizar habilidades y conocimientos. Sin embargo, a menudo los estudiantes con este perfil no están dispuestos a dejar de lado el trabajo o su vida personal para volver al estudio. En este contexto, el aprendizaje on-line representa una magnífica oportunidad para acceder a contenidos académicos sin tener que dejar de lado el trabajo. No obstante, para garantizar el éxito en la provisión de materiales on-line para estudiantes aprendices, las instituciones politécnicas de todo el mundo deben enfrentar dos retos: la transformación de contenidos de aprendizaje práctico en objetos educativos en línea, y la creación de ambientes educativos en los que los estudiantes se sientan involucrados y participativos. Más aún, en un ambiente de aprendizaje en el que el uso de tecnologías Web 2.0 es primordial, es importante considerar también el nuevo rol del profesor, que se ha convertido en facilitador del aprendizaje. Con el fin de analizar la experiencia educativa on-line de estos estudiantes, se distribuyeron 57 encuestas entre los estudiantes registrados en programas de formación on-line. El artículo presenta las conclusiones de la investigación y las compara con las aportaciones que se han hecho en lo relativo a la nueva generación de estudiantes y su uso de las tecnologías, así como el comportamiento registrado por la muestra de la investigación (preferencias y estilos de aprendizaje, su uso de las nuevas tecnologías. Se plantean igualmente oportunidades innovadoras para conectar aprendizaje y contexto laboral y recomendaciones para futuras investigaciones.This paper presents the ongoing research on the

  8. Description and identification of difficulties arising from the application of a cleaning process in operating conditions for the treatment of components used on liquid metal fast reactors (LMFR). A technical designed approach to avoid these situations.

    Science.gov (United States)

    Rodriguez, G; Karpov, A V; Nalimov, Y P

    2001-01-01

    The cleaning process is one of the major maintenance operation for liquid metal fast reactors (LMFRs), both in operation and in their decommissioning stage. Russian and French cleaning processes are briefly described, including problems which have arisen during the processes. It appears that the cause of these problems is always connected to bad draining of the component, resulting in a vigorous reaction between vapour or liquid water and the bulk of sodium. From this discussion, the paper makes major recommendations for the efficient and safe cleaning of sodium wetted components, and proposes several processes which should be developed in order to deal with difficult situations, for example the removal of large amounts of undrainable sodium.

  9. Dimensional Description of On-line Wear Debris Images for Wear Characterization

    Institute of Scientific and Technical Information of China (English)

    WU Tonghai; PENG Yeping; DU Ying; WANG Junqun

    2014-01-01

    As one of the most wear monitoring indicator, dimensional feature of individual particles has been studied mostly focusing on off-line analytical ferrograph. Recent development in on-line wear monitoring with wear debris images shows that merely wear debris concentration has been extracted from on-line ferrograph images. It remains a bottleneck of obtaining the dimension of on-line particles due to the low resolution, high contamination and particle’s chain pattern of an on-line image sample. In this work, statistical dimension of wear debris in on-line ferrograph images is investigated. A two-step procedure is proposed as follows. First, an on-line ferrograph image is decomposed into four component images with different frequencies. By doing this, the size of each component image is reduced by one fourth, which will increase the efficiency of subsequent processing. The low-frequency image is used for extracting the area of wear debris, and the high-frequency image is adopted for extracting contour. Second, a statistical equivalent circle dimension is constructed by equaling the overall wear debris in the image into equivalent circles referring to the extracted total area and premeter of overall wear debris. The equivalent circle dimension, reflecting the statistical dimension of larger wear debris in an on-line image, is verified by manual measurement. Consequently, two preliminary applications are carried out in gasoline engine bench tests of durability and running-in. Evidently, the equivalent circle dimension, together with the previously developed concentration index, index of particle coverage area (IPCA), show good performances in characterizing engine wear conditions. The proposed dimensional indicator provides a new statistical feature of on-line wear particles for on-line wear monitoring. The new dimensional feature conveys profound information about wear severity.

  10. Escapist Motives for On-line Gaming and Strengthening of Weak Ties

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    Due to advances of technology including faster and ubiquitously ac-cessible Internet connection, on-line gaming have grown tremendously in the last couple of years. The aim of this paper is to investigate whether escapist mo-tives for playing games are linked to strengthening of weak ties through...... on-line gaming. The research investigates Facebook and other on-line games separate-ly. A surprising result is that while most of the investigated escapist motives are positively correlated with strengthening of weak ties, the mundane breaking motive is negatively correlated with strengthening...

  11. Escapist Motives for On-line Gaming and Strengthening of Weak Ties

    DEFF Research Database (Denmark)

    Sudzina, Frantisek; Razmerita, Liana

    Due to advances of technology including faster and ubiquitously accessible Internet connection, on-line gaming have grown tremendously in the last couple of years. The aim of this paper is to investigate whether escapist motives for playing games are linked to strengthening of weak ties through on......-line gaming. The research investigates Facebook and other on-line games separately. A surprising result is that while most of the investigated escapist motives are positively correlated with strengthening of weak ties, the mundane breaking motive is negatively correlated with strengthening of weak ties....

  12. On-line and Model-based Approaches to the Visual Control of Action

    OpenAIRE

    Zhao, Huaiyong; Warren, William H.

    2014-01-01

    Two general approaches to the visual control of action have emerged in last few decades, known as the on-line and model-based approaches. The key difference between them is whether action is controlled by current visual information or on the basis of an internal world model. In this paper, we evaluate three hypotheses: strong on-line control, strong model-based control, and a hybrid solution that combines on-line control with weak off-line strategies. We review experimental research on the co...

  13. Key Technique of Austenitic Stainless Steel on-line Solution Treatment

    Institute of Scientific and Technical Information of China (English)

    LI Sheng-li; LI Wei-juan; LIU Shuang; LI Ying; ZHAO Fei

    2004-01-01

    Generally the methods of solution treatment of austenitic stainless steel are bifurcated on-line solution and off-line solution . For a founded enterprise, it is necessary to find out how to get across alterations and search a measure of on -line solution disposal with less investment and higher efficiency. By studying and analysingin laboratory, several key points and the methods settle them are presented, which offers a new route to realize austenitic stainless steel on-line solution. By reducing the cost greatly, it makes the enterprise larger benefits.

  14. FAST Construction Progress

    Science.gov (United States)

    Nan, R. D.; Zhang, H. Y.; Zhang, Y.; Yang, L.; Cai, W. J.; Liu, N.; Xie, J. T.; Zhang, S. X.

    2016-11-01

    The Five-hundred-meter Aperture Spherical radio Telescope (FAST) is a Chinese mega-science project to build the largest single dish radio telescope in the world. A unique karst depression in Guizhou province has been selected as the site to build an active reflector radio telescope with a diameter of 500 m and three outstanding aspects, which enables FAST to have a large sky coverage and the ability of observing astronomical targets with a high precision. Chinese Academy of Sciences and Guizhou province are in charge of FAST construction. The first light of the telescope was expected on September 25, 2016.

  15. Fast Breeder Reactor studies

    Energy Technology Data Exchange (ETDEWEB)

    Till, C.E.; Chang, Y.I.; Kittel, J.H.; Fauske, H.K.; Lineberry, M.J.; Stevenson, M.G.; Amundson, P.I.; Dance, K.D.

    1980-07-01

    This report is a compilation of Fast Breeder Reactor (FBR) resource documents prepared to provide the technical basis for the US contribution to the International Nuclear Fuel Cycle Evaluation. The eight separate parts deal with the alternative fast breeder reactor fuel cycles in terms of energy demand, resource base, technical potential and current status, safety, proliferation resistance, deployment, and nuclear safeguards. An Annex compares the cost of decommissioning light-water and fast breeder reactors. Separate abstracts are included for each of the parts.

  16. Gas cooled fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1972-06-01

    Although most of the development work on fast breeder reactors has been devoted to the use of liquid metal cooling, interest has been expressed for a number of years in alternative breeder concepts using other coolants. One of a number of concepts in which interest has been retained is the Gas-Cooled Fast Reactor (GCFR). As presently envisioned, it would operate on the uranium-plutonium mixed oxide fuel cycle, similar to that used in the Liquid Metal Fast Breeder Reactor (LMFBR), and would use helium gas as the coolant.

  17. Analisis de la adaptacion a la red en las editoriales on line de cinco paises europeos

    National Research Council Canada - National Science Library

    Garcia Orosa, B; Lopez Garcia, X; Gallur Santorum, S

    2013-01-01

    [ES] Introduccion. El articulo analiza los editoriales de periodicos on line de cinco paises europeos con el objetivo principal de realizar una radiografia de sus caracteristicas y su grado de adaptacion a la red. Metodologia...

  18. Modelling of pulverized coal boilers: review and validation of on-line simulation techniques

    Energy Technology Data Exchange (ETDEWEB)

    Diez, L.I.; Cortes, C.; Campo, A. [University of Zaragoza, Zaragoza (Spain). Centro de Investigacion de Recursos y Consumos Energeticos (CIRCE)

    2005-07-01

    Thermal modelling of large pulverized fuel utility boilers has reached a very remarkable development, through the application of CFD techniques and other advanced mathematical methods. However, due to the computational requirements, on-line monitoring and simulation tools still rely on lumped models and semiempirical approaches, which are often strongly simplified and not well connected with sound theoretical basis. This paper reviews on-line modelling techniques, aiming at the improvement of their capabilities, by means of the revision and modification of conventional lumped models and the integration of off-line CFD predictions. The paper illustrates the coherence of monitoring calculations as well as the validation of the on-line thermal simulator, starting from real operation data from a case-study unit. The outcome is that it is possible to significantly improve the accuracy of on-line calculations provided by conventional models, taking into account the singularities of large combustion systems and coupling offline CFD predictions for selected scenarios.

  19. CODE STEM - Moon, Mars, and Beyond; DLESE-Powered On-Line Classroom Project

    Data.gov (United States)

    National Aeronautics and Space Administration — "CODE (COrps DEvelopment) STEM (Science, Technology, Engineering, and Math) ? Moon Mars and Beyond; DLESE-Powered On-Line Classroom" shares the excitement of...

  20. Learning Survival Models with On-Line Simulation Activities in the Actuarial Science Degree

    National Research Council Canada - National Science Library

    Antonio Fernandez-Morales

    2011-01-01

    The aim of this paper is to describe an on-line survival laboratory designed to enhance teaching and learning in the Statistics courses of the Actuarial Science Degree of the Uni-versity of Málaga...

  1. Development of an on-line state estimator for fed-batch filamentous fungal fermentations

    DEFF Research Database (Denmark)

    Mears, Lisa; Stocks, Stuart M.; Albæk, Mads O.

    Bioprocesses can be challenging to model due to complex and non-linear process dynamics [1]. In addition there is a lack of robust, on-line sensors for key parameters of interest in the field, such as substrate, product and biomass concentration [2]. These factors lead to limitations in the ability...... to monitor and control bioprocess systems. There is therefore an interest in state estimation, in order to model these key process states based on available on-line measurements [1]. This work discusses the application of a first principle model to pilot scale filamentous fungal fermentation systems operated...... pressure [4], [5]. This stoichiometric-based coupled process model is successfully applied on-line as a state estimator in order to predict the biomass and product concentration, from robust, available on-line measurements. Such state estimators will be valuable as part of control strategy development...

  2. On-Line Monitoring of Fermentation Processes by Near Infrared and Fluorescence Spectroscopy

    DEFF Research Database (Denmark)

    Svendsen, Carina

    Monitoring and control of fermentation processes is important to ensure high product yield, product quality and product consistency. More knowledge on on-line analytical techniques such as near infrared and fluorescence spectroscopy is desired in the fermentation industry to increase the efficiency...... of on-line monitoring systems. The primary aim of this thesis is to elucidate and explore the dynamics in fermentation processes by spectroscopy. Though a number of successful on-line lab-scale monitoring systems have been reported, it seems that several challenges are still met, which limits the number...... for on-line monitoring if corrections or preventive measures during the quantification are carried out. The findings presented in this thesis have enabled the possibility of obtaining a better process understanding and to ease monitoring and controlling of fermentation processes....

  3. On Line Spectrophotometric Measurement of Uranium and Nitrate in H Canyon

    Energy Technology Data Exchange (ETDEWEB)

    Lascola, R.J.

    2002-10-15

    This report describes the on-line instrumentation developed by the Analytical Development Section of Savannah River Technology Center in support of Highly Enriched Uranium Blend Down processing in H Canyon.

  4. Using a strengths model to build an on-line nursing education program.

    Science.gov (United States)

    Wieck, K Lynn; Alfred, Danita; Haas, Barbara K; Yarbrough, Susan

    2014-01-01

    The on-line environment is the new frontier for academia struggling to define its place in the evolving economy. A concern is how to engage students who maximize their on-line experience and graduate in a timely manner. A strengths model was used as the basis for development of an on-line doctoral nursing program. Upon entering the program, students were given a strengths assessment that focused both students and faculty on the positive attributes students were bringing to their doctoral studies. A positive feedback methodology using on-line discussions in each course was used to support the identified strengths. The optimal picture of a successful entering doctoral student appears to be a person whose top five strengths are learner, achiever, input, connectedness and responsibility. A strengths model promotes a positive learning environment and supports a teacher-learner dynamic where faculty members are encouraged to focus on the students' strengths rather than their challenges.

  5. First on-line $\\beta$-NMR on oriented nuclei magnetic dipole moments of the $\

    CERN Document Server

    Giles, T; Stone, N J; Van Esbroeck, K; White, G; Wöhr, A; Veskovic, M; Towner, I S; Mantica, P F; Prisciandaro, J I; Morrissey, D J; Fedosseev, V; Mishin, V I; Köster, U; Walters, W B

    2000-01-01

    The first fully on-line use of the angular distribution of $\\beta$ - emission in detection of NMR of nuclei oriented at low temperatures is reported. The magnetic moments of the single valence particle, intermediate mass, isotopes $^{67}$Ni($\

  6. Integrated electrochemical sensor array for on-line monitoring of yeast fermentations

    NARCIS (Netherlands)

    Krommenhoek, E.E.; Gardeniers, Johannes G.E.; Bomer, Johan G.; Li, X.; Ottens, M.; van Dedem, G.W.K.; van Leeuwen, M.; van Gulik, W.M.; van der Wielen, L.A.M.; Heijnen, J.J.; van den Berg, Albert

    2007-01-01

    This paper describes the design, modeling, and experimental characterization of an electrochemical sensor array for on-line monitoring of fermentor conditions in both miniaturized cell assays and in industrial scale fertnentations. The viable biomass concentration is determined from impedance

  7. FAST joins Breakthrough programme

    Science.gov (United States)

    Banks, Michael

    2016-11-01

    The 180m Five-hundred-meter Aperture Spherical radio Telescope (FAST) - the world's largest single-aperture radio receiver - has become part of the Breakthrough Listen programme, which launched in July 2015 to look for intelligent life beyond Earth.

  8. CMS Fast Facts

    Data.gov (United States)

    U.S. Department of Health & Human Services — CMS has developed a new quick reference statistical summary on annual CMS program and financial data. CMS Fast Facts includes summary information on total program...

  9. ON-LINE SCHEDULING OF UNIT TIME JOBS WITH REJECTION ON UNIFORM MACHINES

    Institute of Scientific and Technical Information of China (English)

    Shoupeng LIU; Yuzhong ZHANG

    2008-01-01

    The authors consider the problem of on-line scheduling of unit execution time jobs on uniform machines with rejection penalty. The jobs arrive one by one and can be either accepted and scheduled, or be rejected. The objective is to minimize the total completion time of the accepted jobs and the total penalty of the rejection jobs. The authors propose an on-line algorithm and prove that the competitive ratio is 1/2 (2 + ) ≈ 1.86602.

  10. The Study on On-line Scheduling Algorithm of Imprecise Computation under Transient Overload

    Institute of Scientific and Technical Information of China (English)

    WEIZhenhua; HONGBingrong; QIAOYongqiang; CAIZesu; PENGJunjie

    2003-01-01

    Transient overload always occurs in realtime computer system. An on-line scheduling algorithm of imprecise computation is proposed in this paper to deal with it. This algorithm can be sure of getting acceptable computation result under the condition of overload, and at the same time it can improve the computation precision as much as possible. The system model of imprecise computation and the on-line imprecise computation algorithm are elaborated. And the algorithm is proved correct by simulation.

  11. On line high dose static position monitoring by ionization chamber detector for industrial gamma irradiators.

    Science.gov (United States)

    Rodrigues, Ary A; Vieira, Jose M; Hamada, Margarida M

    2010-01-01

    A 1 cm(3) cylindrical ionization chamber was developed to measure high doses on line during the sample irradiation in static position, in a (60)Co industrial plant. The developed ionization chamber showed to be suitable for use as a dosimeter on line. A good linearity of the detector was found between the dose and the accumulated charge, independently of the different dose rates caused by absorbing materials.

  12. On-line marketing - princip aukce mění svět reklamy.

    OpenAIRE

    Jankovič, Zdeněk

    2009-01-01

    Diploma thesis 'On-line marketing - Principle of an auction changes the world of advertising' is about internet as a medium, on-line commercial communications, search engines and performance marketing. This thesis is divided into three parts. First part is about internet as a medium and actual situation on the Czech internet market. Second part describes a marketing communication mix on the internet, forms of online advertisement and pros and cons of online advertising. Third part deals with ...

  13. Preferred Methods of Learning for Nursing Students in an On-Line Degree Program.

    Science.gov (United States)

    Hampton, Debra; Pearce, Patricia F; Moser, Debra K

    Investigators have demonstrated that on-line courses result in effective learning outcomes, but limited information has been published related to preferred teaching strategies. Delivery of on-line courses requires various teaching methods to facilitate interaction between students, content, and technology. The purposes of this study were to understand student teaching/learning preferences in on-line courses to include (a) differences in preferred teaching/learning methods for on-line nursing students across generations and (b) which teaching strategies students found to be most engaging and effective. Participants were recruited from 2 accredited, private school nursing programs (N=944) that admit students from across the United States and deliver courses on-line. Participants provided implied consent, and 217 (23%) students completed the on-line survey. Thirty-two percent of the students were from the Baby Boomer generation (1946-1964), 48% from Generation X (1965-1980), and 20% from the Millennial Generation (born after 1980). The preferred teaching/learning methods for students were videos or narrated PowerPoint presentations, followed by synchronous Adobe Connect educations sessions, assigned journal article reading, and e-mail dialog with the instructor. The top 2 methods identified by participants as the most energizing/engaging and most effective for learning were videos or narrated PowerPoint presentations and case studies. The teaching/learning method least preferred by participants and that was the least energizing/engaging was group collaborative projects with other students; the method that was the least effective for learning was wikis. Baby Boomers and Generation X participants had a significantly greater preference for discussion board (Plearning (Pteaching/learning methods for on-line students. Faculty need to incorporate various teaching methodologies within on-line courses to include both synchronous and asynchronous activities and interactive and

  14. On line high dose static position monitoring by ionization chamber detector for industrial gamma irradiators

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Ary A. [Universidade Estadual de Londrina-Depto de Fisica, Rodovia Celso Garcia Cid, km 38, 086051-990 Londrina (Brazil); Vieira, Jose M. [Instituto de Pesquisas Energeticas e Nucleares-IPEN/CNEN-SP, Prof. Lineu Prestes, 2242-Cidade Universitaria, 05508-900 Sao Paulo (Brazil); Hamada, Margarida M. [Instituto de Pesquisas Energeticas e Nucleares-IPEN/CNEN-SP, Prof. Lineu Prestes, 2242-Cidade Universitaria, 05508-900 Sao Paulo (Brazil)], E-mail: mmhamada@ipen.br

    2010-04-15

    A 1 cm{sup 3} cylindrical ionization chamber was developed to measure high doses on line during the sample irradiation in static position, in a {sup 60}Co industrial plant. The developed ionization chamber showed to be suitable for use as a dosimeter on line. A good linearity of the detector was found between the dose and the accumulated charge, independently of the different dose rates caused by absorbing materials.

  15. FAST Maser Surveys

    Indian Academy of Sciences (India)

    J. S. Zhang

    2014-09-01

    FAST, the Five-hundred meter Aperture Spherical radio Telescope, will become the largest operating single-dish telescope in the coming years. It has many advantages: much better sensitivity for its largest collecting area; large sky coverage due to its innovative design of the active primary surface; extremely radio quiet from its unique location, etc. In this work, I will highlight the future capabilities of FAST to discover and observe both galactic and extragalactic masers.

  16. Rapid Identification and Simultaneous Quantification of Multiple Constituents in Nao-Shuan-Tong Capsule by Ultra-Fast Liquid Chromatography/Diode-Array Detector/Quadrupole Time-of-Flight Tandem Mass Spectrometry.

    Science.gov (United States)

    Li, Panlin; Su, Weiwei; Xie, Chengshi; Zeng, Xuan; Peng, Wei; Liu, Menghua

    2015-07-01

    A rapid and high-sensitive ultra-fast liquid chromatography coupled with a diode-array detector and a quadrupole/time-of-flight mass spectrometry (MS) method was established and validated for the chemical profiling of Nao-shuan-tong capsule (NSTC) and simultaneous quantification of five major constituents. A total of 59 components including monoterpene glycosides, flavonoids, sesquiterpenoids, ketosteroids, thiophenes, organic acids and alkaloids were identified or tentatively characterized in NSTC based on the accurate mass and tandem MS behavior. Five major bioactive constituents were chosen as the chemical indexes of holistic quality evaluation and quantified simultaneously. All calibration curves showed good linear regression (r(2) > 0.9991) in the range 25.2-510, 145-2,900, 1.84-36.8, 2.61-52.2 and 3.25-26.2 μg/mL for gastrodin, paeoniflorin, typhaneoside, β-ecdysterone and isorhamnetin-3-O-neohesperidoside, respectively. It also showed good precision, stability and accuracy for quantification of these five compounds. The limit of detections and limit of quantitations for the analytes ranged from 0.14 to 1.09 μg/mL and from 0.47 to 3.63 μg/mL, respectively. The validated quantification method was applied to analyze 10 batches of commercial NSTC. These results will provide a basis for quality control of the production process and the further pharmacological study in vivo of NSTC.

  17. On-Line Wavelength Calibration of Pulsed Laser for CO2 Differential Absorption LIDAR

    Science.gov (United States)

    Xiang, Chengzhi; Ma, Xin; Han, Ge; Liang, Ailin; Gong, Wei

    2016-06-01

    Differential absorption lidar (DIAL) remote sensing is a promising technology for atmospheric CO2 detection. However, stringent wavelength accuracy and stability are required in DIAL system. Accurate on-line wavelength calibration is a crucial procedure for retrieving atmospheric CO2 concentration using the DIAL, particularly when pulsed lasers are adopted in the system. Large fluctuations in the intensities of a pulsed laser pose a great challenge for accurate on-line wavelength calibration. In this paper, a wavelength calibration strategy based on multi-wavelength scanning (MWS) was proposed for accurate on-line wavelength calibration of a pulsed laser for CO2 detection. The MWS conducted segmented sampling across the CO2 absorption line with appropriate number of points and range of widths by using a tunable laser. Complete absorption line of CO2 can be obtained through a curve fitting. Then, the on-line wavelength can be easily found at the peak of the absorption line. Furthermore, another algorithm called the energy matching was introduced in the MWS to eliminate the backlash error of tunable lasers during the process of on-line wavelength calibration. Finally, a series of tests was conducted to elevate the calibration precision of MWS. Analysis of tests demonstrated that the MWS proposed in this paper could calibrate the on-line wavelength of pulsed laser accurately and steadily.

  18. SkyMouse: A smart interface for astronomical on-line resources and services

    Institute of Scientific and Technical Information of China (English)

    CUI ChenZhou; SUN HuaPing; ZHAO YongHeng; LUO Yu; QI DaZhi

    2008-01-01

    With the development of network and the World Wide Web (WWW), the Internet has been growing and changing dramatically. More and more on-line database systems and different kinds of services are available for astronomy research. How to help users find their way through the jungle of information services becomes an important challenge. Although astronomers have been aware of the importance of interoperability and introduced the concept of Virtual Observatory as a uniform environment for future astronomical on-line resources and services, transparent access to heterogeneous on-line information is still difficult. SkyMouse is a lightweight interface for distributed astronomical on-line resources and services, which is designed and developed by us, i.e., Chinese Virtual Observatory project. Taking ad-vantage of screen word-capturing technology, different kinds of information systems can be queried through simple mouse actions, and results are returned in a uniform web page. SkyMouse is an easy to use application, aiming to show basic information or to create a comprehensive overview of a specific astronomical object. In this paper current status of on-line resources and services access is reviewed; system architecture, features and functions of SkyMouse are described; challenges for intelligent in-terface for on-line astronomical resources and services are discussed.

  19. PROFILES AND PREFERENCES OF ON-LINE MILLENIAL SHOPPERS IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Patricia R. Loubeau

    2014-05-01

    Full Text Available This research seeks to develop a better understanding of the factors affecting on-line purchasing behavior among Generation Y (Gen Y consumers in Bulgaria. Also called millenials and born between the mid-1970s and late 1990s, this generation is especially active on-line and will be a dominant influence shaping e-commerce. An empirical study was conducted based on a written survey of a sample consisting of 367 high school and university students in Bulgaria. The most important reason why Bulgarian young people shop on-line is the pursuit of unique products not locally available, followed by convenience and better pricing, and their favorite category of internet purchases is “Apparel and Accessories.” Bulgarian millennials are using the internet to shop for trendy fashion and to obtain a variety of brands that are unavailable locally. Like other regions of the world, concern about financial transactions security is a major barrier limiting the willingness to shop on-line in Bulgaria. Unlike other markets where on-line music purchases are growing, high levels of digital piracy in Bulgaria strongly discourage Bulgarian students from purchasing music on-line. One limitation of this study arises because of its reliance on a convenience sample of students from medium sized cities in Southern Bulgaria. Further research employing stratified random sampling across Bulgaria is needed to assess whether the findings are broadly generalizable for the Gen Y population.

  20. Process Analytical Technology and On-Line Spectroscopic Measurements of Chemical Meat Quality

    DEFF Research Database (Denmark)

    Sørensen, Klavs Martin

    This thesis deals with process analytical technology and how it can be implemented in the meat industry through on-line grading of chemical meat quality. The focus will be on two applications, namely the rapid quality control of fat quality and the development of a method for on-line detection of...... quality, but also with environmental issues such as energy and water use and animal welfare. Future research into the technologies will ultimately allow broad on-line screening of biomarkers, leading to on-line metabolomics......This thesis deals with process analytical technology and how it can be implemented in the meat industry through on-line grading of chemical meat quality. The focus will be on two applications, namely the rapid quality control of fat quality and the development of a method for on-line detection...... of boar taint. The chemical makeup of fat has a large effect on meat cut quality. Fat quality has traditionally been determined by methylation of a tissue sample followed by chromatography on a GC-MS system, elucidating the composition of the individual fatty acids. As this procedure typically takes far...

  1. 基于形函数方法快速识别结构动态荷载的试验验证%Experimental validation of a fast dynamic load identification method based on load shape function

    Institute of Scientific and Technical Information of China (English)

    张青霞; 段忠东; Lukasz Jankowski; 王丰

    2011-01-01

    A dynamic load identification method was introduced and complemented, in which the force was approximated by using the shape functions in die finite element theory. The computational work was reduced a lot by calculating the weights of shape functions instead of indentifying the discrete load time history and the performance of the deconvolution method in the condition of long sampling time period or high sampling frequency was improved. Moreover, the ill-conditioning of the inverse problem was corrected, and the robustness to noise was strengthened. The numerical example of a continuous beam verifies that the load can be identified precisely by this method under the influence of 5% Gaussian noise pollution in the signals. In a cantilever beam experiment, via the measured structural responses, the method enables the online load identification which is performed repeatedly in a moving time window.%在动态荷载识别中常常由于矩阵的病态性影响识别的精度,利用有限元理论中的形函数逼近荷载曲线,将识别离散的荷载历程转化为计算有限的形函数权重,从而显著改善反卷积法识别荷载中存在的采样时间长或采样频率高时数值求解困难的问题;并能改善反问题的病态性,提高对噪声的鲁棒性.一个连续梁的数值算例比较验证了该方法在5%的高斯噪声影响下能精确地识别未知荷载.悬臂梁试验中,通过实测的结构动态响应,在移动时间窗内利用荷载形函数方法可以实现激励的在线识别.

  2. A new on-line, in-tube pre-column derivatization technique for high performance liquid chromatographic determination of azithromycin in human serum.

    Science.gov (United States)

    Bahrami, Gholamreza; Mohammadi, Bahareh

    2006-01-18

    Pre-column derivatization methods for high performance liquid chromatographic assay of specific pharmaceutical agents using 9-fluorenylmethyl chloroformate (FMOC-Cl) have received special attention because highly fluorescent and stable adducts are provided by these methods. However, unlike the post-column on-line techniques, long derivatization time is needed and the reaction cannot be well controlled. A new, sensitive and fast pre-column on-line derivatization technique coupled with high-performance liquid chromatography using FMOC-Cl as labeling agent is described and validated for determination of azithromycin in human serum. After extraction of the drug from serum, the residue was reconstituted in mixture of acetonitrile-phosphate buffer (3:1, v/v; pH 8.5) and directly injected onto the chromatographic system. Continuous on-line derivatization and analysis of the compounds were successfully performed using in-tube elution of FMOC-Cl. The total time needed for derivatization and chromatographic analysis of the drug was 13 min. The assay was reliable and reproducible, with limit of quantification of 10 ng/ml. The described technique may offer significant advantages over existing off-line derivatization methods using FMOC-Cl.

  3. Fasting and Urinary Stones

    Directory of Open Access Journals (Sweden)

    Ali Shamsa

    2013-11-01

    Full Text Available Introduction: Fasting is considered as one of the most important practices of Islam, and according to Prophet Mohammad, fasting is obligatory upon Muslims. The aim of this study is to evaluate the effects of fasting on urinary stones. Materials and Methods: Very few studies have been carried out on urinary stones and the effect of Ramadan fasting. The sources of the present study are Medline and articles presented by local and Muslim researchers. Meanwhile, since we are acquainted with three well-known researchers in the field of urology, we contacted them via email and asked for their professional opinions. Results: The results of studies about the relationship of urinary stones and their incidence in Ramadan are not alike, and are even sometimes contradictory. Some believe that increased incidence of urinary stones in Ramadan is related not to fasting, but to the rise of weather temperature in hot months, and an increase in humidity. Conclusion: Numerous biological and behavioral changes occur in people who fast in Ramadan and some researchers believe that urinary stone increases during this month.

  4. Fasting and urinary stones

    Directory of Open Access Journals (Sweden)

    Ali Shamsa

    2013-12-01

    Full Text Available Introduction: Fasting is considered as one of the most important practices of Islam, and according to Prophet Mohammad, fasting is obligatory upon Muslims. The aim of this study is to evaluate the effects of fasting on urinary stones. Materials and Methods:Very few studies have been carried out on urinary stones and the effect of Ramadan fasting. The sources of the present study are Medline and articles presented by local and Muslim researchers. Meanwhile, since we are acquainted with three well-known researchers in the field  of urology, we contacted them via email and asked for their professional opinions. Results:The results of studies about the relationship of urinary stones and their incidence in Ramadan are not alike, and are even sometimes contradictory. Some believe that increased incidence of urinary stones in Ramadan is related not to fasting, but to the rise of weather temperature in hot months, and an increase in humidity. Conclusion: Numerous biological and behavioral changes occur in people who fast in Ramadan and some researchers believe that urinary stone increases during this month.

  5. Development of an artificial neural network model for on-line thermal margin estimation of a nuclear reactor core

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Koon

    1992-02-15

    One of the key safety parameters related to thermal margin in a Pressurized Water Reactor (PWR) core, is Departure from Nucleate Boiling Ratio (DNBR), which is to be assessed and continuously monitored during operation via either an analog or a digital monitoring system. The digital monitoring system, in general, allows more thermal margin than the analog system through the on-line computation of DNBR using the measured parameters as inputs to a simplified, fast running computer code. The purpose of this thesis is to develop an advanced method for on-line DNBR estimation by introducing an artifactual neural network model for best-estimation of DNBR at the given reactor operating conditions. the neural network model, consisting of three layers with five operating parameters in the input layer, provides real-time prediction accuracy of DNBR by training the network against the detailed simulation results for various operating conditions. The overall training procedure is developed to learn the characteristics of DNBR behaviour in the reactor core. First, a set of random combination of input variables is generated by Latin Hypercube Sampling technique performed on a wide range of input parameters. Second, the target values of DNBR to be referenced for training are calculated using a detailed simulation code, COBRA-IV. Third, the optimized training input data are selected. Then, training is performed using an Error Back Propagation algorithm. After completion of training, the network is tested on the examining data set in order to investigate the generalization capability of the network responses for the steady state operating condition as well as for the transient situations where DNB is of a primary concern. The test results show that the values of DNBR predicted by the neural network are maintained at a high level of accuracy for the steady state condition, and are in good agreements with the transient situation, although slightly conservative as compared to those

  6. Methodological study of VITEK-MS assisted by separation gel tube for fast identification of positive blood culture bacteria%分离胶辅助VITEK-MS质谱仪快速鉴定血培养阳性菌的方法学研究

    Institute of Scientific and Technical Information of China (English)

    蒋月婷; 黎健成; 易建云; 陈定强

    2016-01-01

    Objective To investigate the method of the separation gel vacuum tube combined with matrix‐assisted laser desorp‐tion/ionization time of flight mass spectrometry system (VITEK‐MS) for fasting identifying positive blood culture bacteria .Methods Fifty cases of positive blood culture by the BacT/ALERT3D blood culture system and Gram‐negative bacteria by direct staining in the First Affiliated Hospital of Guangzhou University from March to October 2015 were collected .The bacteria were directly ex‐tracted from the blood culture bottle by the separation gel tube and performed the fast identification by adopting the VITEK‐MS system .At the same time the bacteria were performed the subcultivation and identification .then the coincidence of this method was compared .Results Among 50 cases of Gram‐negative bacteria by positive blood culture ,21 cases of bacteria were not identified ,29 cases of bacteria were identified ,the positive rate was 58 .0% .the coincidence rate with the conventional identification results was 96 .6% ;the method of separation gel combined with VITEK‐MS was nearly 24 h in advance compared with the traditional method . Conclusion Adopting the separation gel vacuum tube combined with VITEK‐MS for identifying bacteria has the higher coincidence rate of positive blood culture Gram negative bacteria ,can greatly shorten the identification time ,this method is rapid and simple .%目的:探讨用分离胶采血管联合基质辅助激光解析电离飞行时间质谱系统(VITEK‐MS)快速鉴定血培养阳性菌的方法。方法收集2015年3~10月广州医科大学附属第一医院BacT/ALERT3D血培养仪报阳性,且直接涂片染色为革兰阴性菌的血培养标本50例,通过分离胶采血管直接从血培养瓶中提取细菌,采用VITEK‐MS 对细菌进行快速鉴定;同时用常规方法对细菌进行转种培养及鉴定,比较该方法的鉴定符合率。结果50例血培养

  7. Continuous Flow Liquid Microjunction Surface Sampling Probe Connected On-line with HPLC/MS for Spatially Resolved Analysis of Small Molecules and Proteins

    Energy Technology Data Exchange (ETDEWEB)

    Van Berkel, Gary J [ORNL; Kertesz, Vilmos [ORNL

    2013-01-01

    RATIONALE: A continuous flow liquid microjunction surface sampling probe extracts soluble material from surfaces for direct ionization and detection by MS. Demonstrated here is the on-line coupling of such a probe with HPLC/MS enabling extraction, separation and detection of small molecules and proteins from surfaces in a spatially resolved (~0.5 mm diameter spots) manner. Methods: A continuous flow liquid microjunction surface sampling probe was connected to a 6-port, 2-position valve for extract collection and injection to an HPLC column. A QTRAP 5500 hybrid triple quadrupole linear ion trap equipped with a Turbo V ion source operated in positive ESI mode was used for all experiments. System operation was tested with extraction, separation and detection of propranolol and associated metabolites from drug dosed tissues and proteins from dried sheep blood spots on paper. Results: Confirmed in the tissue were the parent drug and two different hydroxypropranolol glucuronides. The mass spectrometric response for these compounds from different locations in the liver showed an increase with increasing extraction time (5, 20 and 40 s extractions). For on-line separation and detection/identification of extracted proteins from dried sheep blood spots, two major protein peaks dominated the chromatogram and could be correlated with the expected masses for the hemoglobin and chains. Conclusions: Spatially resolved sampling, separation, and detection of small molecules and proteins from surfaces can be accomplished using a continuous flow liquid microjunction surface sampling probe coupled on-line with HPLC/MS detection.

  8. 一种基于逆向迭代搜索的快速隐通道检测方法%Fast reverse searching method for covert channels identification

    Institute of Scientific and Technical Information of China (English)

    张立勇; 王献青; 陈平; 邓凡; 孔德兰

    2011-01-01

    提出了一种基于静态分析的隐通道自动检测方法.采用完整语法与语义分析手段完成原始信息流提取,保留了局部变量导致的间接信息流,定义了库函数信息流规则以及信息流推导规则,提高了信息流收集的准确性与完整性;采用基于信息流图的带约束逆向深度优先搜索算法,实现了潜在隐通道检测,与传统共享资源矩阵法与正向遍历信息流图方法相比,该方法具有更高的检测效率;并通过语法及语义规则实现了伪隐通道的筛选,减少了误报.%A method for identifing covert channels automatically based on static analysis is proposed.The method adopts typical syntax and semantic analysis technology to implement initial information flow extraction, retains indirect information flows produced by local variables and establishes information flow rules for library functions and information flow deduction, which enhanceds the accuracy and integrality of information flow collection.Based on the information flow graph, a constrained reverse depth-first traversing (DFT) algorithm is designed to iteratively detect potential covert channels, and the efficiency of covert channel detection is thus improved.Finally, syntax and semantic rules are discussed to eliminate illegal covert channels.

  9. ATM Security Using Fingerprint Biometric Identifer: An Investigative Study

    OpenAIRE

    Moses Okechukwu Onyesolu; Ignatius Majesty Ezeani

    2012-01-01

    The growth in electronic transactions has resulted in a greater demand for fast and accurate user identification and authentication. Access codes for buildings, banks accounts and computer systems often use personal identification numbers (PIN's) for identification and security clearances. Conventional method of identification based on possession of ID cards or exclusive knowledge like a social security number or a password are not all together reliable. An embedded fingerprint biometric auth...

  10. Enhancing communication skills for pediatric visits through on-line training using video demonstrations

    Directory of Open Access Journals (Sweden)

    Wissow Larry

    2008-02-01

    Full Text Available Abstract Background Training in communication skills for health professionals is important, but there are substantial barriers to individual in-person training for practicing clinicians. We evaluated the feasibility and desirability of on-line training and sought suggestions for future courses. Methods Based on successful in-person curricula for communication skills and our previous on-line curricula, we created an on-line course consisting of 28 modules (4.75 hours CME credit about communication skills during pediatric visits that included a mental health concern; each module included a brief case, a multiple choice question, an explanation, and a 1–2 minute video demonstrating key skills. Specific communication skills included: greeting, setting an agenda, discussing diagnosis and treatment, and managing negative interactions. The course was announced by emails in spring, 2007; the course was available on-line for 60 days; we aimed to enroll 50 clinicians. Outcomes were analyzed for those who evaluated the course within 75 days of its initial availability. Results Overall, 61 clinicians registered, of whom most were nurses (N = 24, physicians (N = 22, or psychologists or social workers (N = 12. Of the 36 (59% clinicians who evaluated the course, over 85% agreed that all course objectives had been met; over 90% reported greater confidence in greetings and agenda-setting; and over 80% reported greater confidence in discussing diagnosis and treatment and managing negative interactions. Nearly all, 97% would recommend the course to other clinicians and trainees. Suggestions for improvement included a library of additional video vignettes and written materials to accompany the on-line training. Conclusion On-line training in communication skills for pediatric mental health visits is feasible, desirable and associated with increased confidence in key skills. Positive feedback from clinicians suggests that a comparison of on-line versus in

  11. Fast identification of dead burnt magnesite in nonmetallic minerals by Fourier transform infrared spectrometry%傅立叶变换红外光谱法快速鉴别非金属矿物中重烧镁

    Institute of Scientific and Technical Information of China (English)

    武素茹; 谷松海; 马德起; 李权斌; 王虹

    2013-01-01

    重烧镁外观与高岭土、白云石及硅灰石等矿物的外观极为相似,常被混入这些矿石中向境外走私.为了快速鉴别这些矿物中的重烧镁,实验采用傅里叶变换红外光谱技术分别研究了具有不同重烧镁含量的三种矿物其光谱特征,并与重烧镁及不合重烧镁的矿物谱图进行比对.结果表明,当这些矿物中混入一定量的重烧镁时,重烧镁的红外特征吸收峰依然明显存在.当只含有10%的重烧镁,根据谱图的特征变化,依然能够鉴别出这些矿物中混入的重烧镁,即鉴定这些矿物中重烧镁的检出限为10%.方法对实际样品进行了分析,分析结果与化学法相符.%The appearance of dead burnt magnesite was very similar to kaolin, dolomite and wollaston-ite ores, so it was usually mixed into these minerals for abroad smuggling. In order to fast identify the dead burnt magnesite in these minerals, the Fourier transform infrared spectrum technology was used to study the spectral signature of three minerals containing various contents of dead burnt magnesite. Then, the spectra were compared with those of dead burnt magnesite and minerals without dead burnt magnesite. The results showed that, when certain amount of dead burnt magnesite was mixed into these minerals, the infrared characteristic absorption peak of dead burnt magnesite still existed. When the content of dead burnt magnesite was 10% , it could be also identified based on the change of characteristic spectrum. In other words, the detection limit of dead burnt magnesite in these minerals was 10%. The proposed method was applied to the analysis of actual samples and the results were consistent with the chemical method.

  12. On-line identification of vehicle fuel consumption for energy and emission management: an LTP System Analysis

    NARCIS (Netherlands)

    Kessels, J.T.B.A.; Sijs, J.; Hermans, R.M.; Damen, A.A.H.; Bosch, P.P.J. van den; Papp, Z.; Lazar, M.

    2008-01-01

    Abstract—An Energy Management (EM) system traditionally relies on (quasi) static maps offering efficiency parameters of the vehicle powertrain. During a vehicle’s life span, these maps lose validity, so optimal performance for EM is not assured. This paper presents a proof-of-concept for a novel mea

  13. On-Line, Gyro-Based, Mass-Property Identification for Thruster-Controlled Spacecraft Using Recursive Least Squares

    Science.gov (United States)

    Wilson, Edward; Lages, Chris; Mah, Robert; Clancy, Daniel (Technical Monitor)

    2002-01-01

    Spacecraft control, state estimation, and fault-detection-and-isolation systems are affected by unknown v aerations in the vehicle mass properties. It is often difficult to accurately measure inertia terms on the ground, and mass properties can change on-orbit as fuel is expended, the configuration changes, or payloads are added or removed. Recursive least squares -based algorithms that use gyro signals to identify the center of mass and inverse inertia matrix are presented. They are applied in simulation to 3 thruster-controlled vehicles: the X-38 and Mini-AERCam under development at NASA-JSC, and the SAM, an air-bearing spacecraft simulator at the NASA-Ames Smart Systems Research Lab (SSRL).

  14. On-line iron loss resistance identification by a state observer for rotor-flux-oriented control of induction motor

    Energy Technology Data Exchange (ETDEWEB)

    Barrera, Pablo M. de la; Bossio, Guillermo R.; Garcia, Guillermo O. [Grupo de Electronica Aplicada (GEA), Facultad de Ingenieria, UNRC, Ruta Nacional 36 Km. 601, X5804BYA, Rio Cuarto (Argentina); Solsona, Jorge A. [Instituto de Investigaciones en Ingenieria Electrica ' ' Alfredo Desages' ' , Departamento de Ingenieria Electrica y de Computadoras, UNS, Av. Alem 1253 (8000) Bahia Blanca (Argentina)

    2008-10-15

    A rotor flux state observer considering iron loss, for an Induction Motor (IM), is proposed. The aim of this proposal is to avoid detuning caused by the IM iron loss on a field-oriented control (FOC). An adaptive scheme for the K{sub Fe}, a parameter that represents the IM iron loss, is also proposed. The main objective of this scheme is to improve the dynamic response of control by compensating the variations of iron losses due to possible variations in the stator core characteristics. Simulation results demonstrated that the observer and the adaptive scheme showed a good performance fulfilling then the objectives. (author)

  15. Ultra-fast timing with plastic scintillators

    Energy Technology Data Exchange (ETDEWEB)

    Hoischen, Robert [Department of Physics, Lund University, S-22100 Lund (Sweden); Helmholtzzentrum fuer Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Pietri, Stephane; Prokopowicz, Wawrzyniec; Schaffner, Henning; Gerl, Juergen; Wollersheim, Hans Juergen; Kurz, Nikolaus [Helmholtzzentrum fuer Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Rudolph, Dirk [Department of Physics, Lund University, S-22100 Lund (Sweden)

    2009-07-01

    Fast timing detectors for time-of-flight measurements are essential identification tools for isotopes studied at fragment separators at major heavy-ion research facilities. While today's standard technique of utilizing a plastic scintillator read out by few photomultiplier tubes proofs to be efficient, it does not provide the required time resolution for future key experiments at, for example, the Super-FRS at FAIR. A common present-day approach is to use diamond detectors instead. While they do provide a better time resolution compared to scintillators, they are more difficult to use and far more expensive. Results from tests using a new design approach with standard materials will be presented. This leads to a much improved performance, but remains both cost-efficient, compact, and reliable. The design goals and how to accomplish them will be exemplified by the LYCCA (Lund-York-Cologne CAlorimeter) detector aiming for fast-beam experiments at HISPEC within NUSTAR.

  16. On-Line Retrieval System Design; Part V of Scientific Report No. ISR-18, Information Storage and Retrieval...

    Science.gov (United States)

    Cornell Univ., Ithaca, NY. Dept. of Computer Science.

    On-line retrieval system design is discussed in the two papers which make up Part Five of this report on Salton's Magical Automatic Retriever of Texts (SMART) project report. The first paper: "A Prototype On-Line Document Retrieval System" by D. Williamson and R. Williamson outlines a design for a SMART on-line document retrieval system…

  17. The fast code

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, L.N.; Wilson, R.E. [Oregon State Univ., Dept. of Mechanical Engineering, Corvallis, OR (United States)

    1996-09-01

    The FAST Code which is capable of determining structural loads on a flexible, teetering, horizontal axis wind turbine is described and comparisons of calculated loads with test data are given at two wind speeds for the ESI-80. The FAST Code models a two-bladed HAWT with degrees of freedom for blade bending, teeter, drive train flexibility, yaw, and windwise and crosswind tower motion. The code allows blade dimensions, stiffnesses, and weights to differ and models tower shadow, wind shear, and turbulence. Additionally, dynamic stall is included as are delta-3 and an underslung rotor. Load comparisons are made with ESI-80 test data in the form of power spectral density, rainflow counting, occurrence histograms, and azimuth averaged bin plots. It is concluded that agreement between the FAST Code and test results is good. (au)

  18. A fast friend

    Institute of Scientific and Technical Information of China (English)

    高怡

    2010-01-01

    我们都知道fast food的意思是“快餐”。那fast friend能解释为“快速或速成的朋友”吗?也许你会说:“什么是速成朋友呀?It doesn’t make sense.”没错,交朋友怎么会有速成的呢?原来;fast还有一个意思是“忠实的、牢固的”,所以a fast friend的真正意思是“可靠、忠实的朋友”。

  19. Fast Distributed Gradient Methods

    CERN Document Server

    Jakovetic, Dusan; Moura, Jose M F

    2011-01-01

    The paper proposes new fast distributed optimization gradient methods and proves convergence to the exact solution at rate O(\\log k/k), much faster than existing distributed optimization (sub)gradient methods with convergence O(1/\\sqrt{k}), while incurring practically no additional communication nor computation cost overhead per iteration. We achieve this for convex (with at least one strongly convex,) coercive, three times differentiable and with Lipschitz continuous first derivative (private) cost functions. Our work recovers for distributed optimization similar convergence rate gains obtained by centralized Nesterov gradient and fast iterative shrinkage-thresholding algorithm (FISTA) methods over ordinary centralized gradient methods. We also present a constant step size distributed fast gradient algorithm for composite non-differentiable costs. A simulation illustrates the effectiveness of our distributed methods.

  20. Research of on-line monitoring method for insulation condition of power transformer bushing

    Science.gov (United States)

    Xia, Jiuyun; Qian, Zheng; Yu, Hao; Yao, Junda

    2016-01-01

    The power transformer is the key equipment of the power system; its insulation condition will directly influence the security and reliability of the power system. Thus, the on-line monitoring of power transformer is urgently required in order to guarantee the normal operation of the power system. Moreover, the dielectric loss factor is a significant parameter reflecting the condition of transformer bushing, so the on-line measurement of dielectric loss factor is really important. In this paper, the phase-to-phase comparison method is selected as the on-line monitoring method based on the overall analysis and discussion of the existing on-line monitoring methods. At first, the harmonic analysis method is utilized to calculate the dielectric loss of each phase of the three-phase transformer bushing, and then the differences of dielectric loss between every two phases are calculated and analyzed. So the insulation condition of each bushing could be achieved based on the careful analysis of different phase-to-phase dielectric loss. The simulation results of phase-to-phase comparison method are carried out in this paper, and the validity is verified. At last, this method is utilized in an actual equipment of on-line monitoring.

  1. Comportamento do Consumidor On-line: a perspectiva da teoria do fluxoOn-line Consumer Behavior: the flow theory perspectiveComportamiento del consumidor On-line: la perspectiva de la teoría del flujo

    Directory of Open Access Journals (Sweden)

    FARIAS, Salomão Alencar de

    2008-03-01

    Full Text Available RESUMOEste artigo investiga o comportamento do consumidor on-line com base no fluxo, definido como a sensação holística que as pessoas sentem quando agem com total envolvimento em uma atividade (CSIKSZENTMIHALYI, 1975. Emprega-se essa teoria para melhor compreender o comportamento de compra pela Internet, embora seja um conceito ainda confuso na literatura do comportamento do consumidor, pois que não existe um consenso a respeito de quais os fatores antecedem, caracterizam ou são conseqüências do estado de fluxo. Desse modo, esta pesquisa buscou identificar os construtos, relacionados ao estado de fluxo, que devem fazer parte de um esquema de comportamento de compra on-line, além de indicar qual a sua aplicabilidade para o alcance da satisfação do consumidor na compra pela rede. Para tanto, foi utilizada uma metodologia de caráter descritivo com aplicação de um survey junto a uma amostra de 237 consumidores do varejo eletrônico. Os dados coletados foram analisados por meio de técnicas estatísticas multivariadas. Os resultados indicaram que o ambiente on-line e a telepresença antecedem o fluxo que, por sua vez, está associado ao comportamento exploratório, efeito positivo do processo de navegação, compra e satisfação com o processo de compra.ABSTRACTThis article investigates the on-line consumer behavior based on the flow theory, defined as the holistic sensation that people feel when acting with total involvement in an activity (CSIKSZENTMIHALYI, 1975. This theory has been used for better understanding the purchase behavior through the Internet, although this concept is still not sufficiently clear in consumer behavior literature, since it does not exist a consensus regarding which factors that precede, characterize or are consequences of the flow state. Thus, the present research was aimed at identifying the constructs related to the flow state that must be part of an on-line purchase behavior framework, indicating which

  2. Fast ejendom II

    DEFF Research Database (Denmark)

    Munk-Hansen, Carsten

    Fremstillingen påviser, at lov om forbrugerbeskyttelse ved erhvervelse af fast ejendom mv. lider af en række svagheder og at ankenævnspraksis bevæger sig væk fra retspraksis på en række områder.......Fremstillingen påviser, at lov om forbrugerbeskyttelse ved erhvervelse af fast ejendom mv. lider af en række svagheder og at ankenævnspraksis bevæger sig væk fra retspraksis på en række områder....

  3. Moms og fast ejendom

    DEFF Research Database (Denmark)

    Edlund, Hans Henrik

    1999-01-01

    I artiklen gives et overblik over, hvorledes fast ejendom behandles momsmæssigt. Derfor findes en kort skitsering af reglerne for moms på byggearbejder, afgrænsningen mellem momspligtig og momsfri udlejning, muligheden for frivillig registrering af udlejning samt opgørelse af reguleringsforpligte......I artiklen gives et overblik over, hvorledes fast ejendom behandles momsmæssigt. Derfor findes en kort skitsering af reglerne for moms på byggearbejder, afgrænsningen mellem momspligtig og momsfri udlejning, muligheden for frivillig registrering af udlejning samt opgørelse af...

  4. Fast Josephson vortex

    Energy Technology Data Exchange (ETDEWEB)

    Malishevskii, A.S.; Silin, V.P.; Uryupin, S.A

    2002-12-30

    For the magnetically coupled waveguide and long Josephson junction we gave the analytic description of two separate velocity domains where the free motion of traveling vortex (2{pi}-kink) exists. The role of the mutual influence of waveguide and long Josephson junction is discussed. It is shown the possibility of the fast vortex motion with the velocity much larger than Swihart velocity of Josephson junction and close to the speed of light in the waveguide. The excitation of motion of such fast Josephson vortex is described.

  5. ATLAS fast physics monitoring

    Indian Academy of Sciences (India)

    Karsten Köneke; on behalf of the ATLAS Collaboration

    2012-11-01

    The ATLAS experiment at the Large Hadron Collider is recording data from proton–proton collisions at a centre-of-mass energy of 7 TeV since the spring of 2010. The integrated luminosity has grown nearly exponentially since then and continues to rise fast. The ATLAS Collaboration has set up a framework to automatically process the rapidly growing dataset and produce performance and physics plots for the most interesting analyses. The system is designed to give fast feedback. The histograms are produced within hours of data reconstruction (2–3 days after data taking). Hints of potentially interesting physics signals obtained this way are followed up by physics groups.

  6. Ionization and excitation of lithium atoms by fast charged particle impact: identification of mechanisms for double K-shell vacancy production as a function of the projectile charge and velocity; Ionisation et excitation de l'atome de lithium par impact de particules chargees rapides: Identification des mecanismes de creation de deux lacunes en couche K du lithium en fonction de la charge et de la vitesse du projectile

    Energy Technology Data Exchange (ETDEWEB)

    Rangama, J

    2002-11-01

    Ionization and excitation of lithium atoms by fast charged particle impact: identification of mechanisms for double K-shell vacancy production as a function of projectile charge and velocity. Auger electron spectroscopy is used for an experimental investigation of ionization and excitation of lithium atoms by ions (Kr34{sup +} and Ar18{sup +}) and electrons at high impact velocities (from 6 to 60 a.u.). In particular, relative contributions of the mechanisms responsible for lithium K-shell ionization-excitation are determined for various projectile charges Zp and velocities vp. A large range of perturbation parameters |Zp|/vp is explored (|Zp|/vp = 0,05 - 0,7 a.u.). From single K-shell excitation results, it appears that the projectile-electron interaction gives mainly rise to a dipole-like transition 1s -> np Concerning K-shell ionization-excitation, the separation of the TS2 (two independent projectile-electron interactions) and TS1 (one projectile-electron interaction) mechanisms responsible for the formation of the 2snp 1,3P and 2sns 1,3S lithium states is performed. In TS1 process, the projectile-electron interaction can be followed by an electron-electron interaction (dielectronic process) or by an internal rearrangement of the residual target after a sudden potential change (shake process). From Born theory, ab initio calculations are performed. The good agreement between theoretical and experimental results confirms the mechanism identification. For the production of P states, TS1 is found to be strongly dominant for small |Zp|/vp values and TS2 is found to be most important for large |Zp|/vp values. Since P states cannot be formed significantly via a shake process, the TS1 and TS2 separation provides a direct signature of the dielectronic process. On the other hand, the TS1 process is shown to be the unique process for producing the S states. At the moment, only the shake aspect of the TS1 process can explain the fact that the 2s3s configuration is

  7. A New On-Line Detecting Apparatus of the Residual Chlorine in Disinfectant for Fresh-Cut Vegetables

    Science.gov (United States)

    Hu, Chao; Su, Shu-Qiang; Li, Bao-Guo; Liu, Meng-Fang

    With the fast development of modern food and beverage industry, fresh-cut vegetables have wider application than before. During the process of sterilization in fresh-cut vegetables, the concentration of chloric disinfectant is usually so high that the common sensor can't be used directly on the product line. In order to solve this problem, we have invented a new detecting apparatus which could detect high concentration of chloric disinfectant directly. In this paper, the working principle, main monitor indicators, application and technical creations of the on-line apparatus have been discussed, and we also carried on the experimental analysis for its performance. The actual demands in factory could be met when the detecting flux is 2L/min, the dilution ratio is 15 and input amount of the disinfectant is 200ml per time, the max of the detecting deviation achieves ±4.8ppm(mg/L). The main detecting range of residual chlorine is 0~300ppm.

  8. A small-scale air-cathode microbial fuel cell for on-line monitoring of water quality.

    Science.gov (United States)

    Di Lorenzo, Mirella; Thomson, Alexander R; Schneider, Kenneth; Cameron, Petra J; Ieropoulos, Ioannis

    2014-12-15

    The heavy use of chemicals for agricultural, industrial and domestic purposes has increased the risk of freshwater contamination worldwide. Consequently, the demand for efficient new analytical tools for on-line and on-site water quality monitoring has become particularly urgent. In this study, a small-scale single chamber air-cathode microbial fuel cell (SCMFC), fabricated by rapid prototyping layer-by-layer 3D printing, was tested as a biosensor for continuous water quality monitoring. When acetate was fed as the rate-limiting substrate, the SCMFC acted as a sensor for chemical oxygen demand (COD) in water. The linear detection range was 3-164 ppm, with a sensitivity of 0.05 μA mM(-1) cm(-2) with respect to the anode total surface area. The response time was as fast as 2.8 min. At saturating acetate concentrations (COD>164 ppm), the miniature SCMFC could rapidly detect the presence of cadmium in water with high sensitivity (0.2 μg l(-1) cm(-2)) and a lower detection limit of only 1 μg l(-1). The biosensor dynamic range was 1-25 μg l(-1). Within this range of concentrations, cadmium affected only temporarily the electroactive biofilm at the anode. When the SCMFCs were again fed with fresh wastewater and no pollutant, the initial steady-state current was recovered within 12 min.

  9. On-line Determination of Zinc in Water and Biological Samples after Its Preconcentration onto Zincon Anchored Polyurethane Foam.

    Science.gov (United States)

    Azeem, Sami M Abdel; Hanafi, Hassan A; El-Shahat, M F

    2015-01-01

    A fast and sensitive on-line procedure for the determination of zinc in water and biological samples was developed. Zinc was preconcentrated in a mini-column packed with polyurethane foam (PUF) chemically modified with zincon via -N=N- bonding. The optimal conditions for preconcentration were pH 8.5 and sample flow rate of 4.0 mL min(-1). Quantitative desorption of Zn(II) was obtained by 0.1 mol L(-1) hydrochloric acid and subsequent spectrophotmetric determination using 4-(2-pyridylazo)-resorcinol at 498 nm. The obtained detection limit was found to be 3.0 ng mL(-1), precision (RSD) was 4.8 and 6.7% at 20 and 110 ng mL(-1), respectively, for 60 s preconcentration time and enrichment factor was 31. The linearity range was from 10 to 120 ng mL(-1) and maximum sample throughput was 20 h(-1). Finally, the method was successfully applied to the determination of zinc in tap water, Nile River water and human urine samples with RSD in the range of 1.1 - 8.3%.

  10. On-Line Life Monitoring Technique for Tube Bundles of Boiler High-Temperature Heating Surface

    Institute of Scientific and Technical Information of China (English)

    Yang Dong; Wang Zhongyuan

    2005-01-01

    High-temperature heating surface such as superheater and reheater of large-sized utility boiler all experiences a relatively severe working conditions. The failure of boiler tubes will directly impact the safe and economic operation of boiler. An on-line life monitoring model of high-temperature heating surface was set up according to the well-known L-M formula of the creep damages. The tube wall metal temperature and working stress was measured by on-line monitoring, and with this model, the real-time calculation of the life expenditure of the heating surface tube bundles were realized. Based on the technique the on-line life monitoring and management system of high-temperature heating surface was developed for a 300 MW utility boiler. An effective device was thus suggested for the implementation of the safe operation and the condition-based maintenance of utility boilers.

  11. On-line Shopping on B2C Markets in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Pilík Michal

    2012-12-01

    Full Text Available The paper deals with the e-commerce theory and is aimed primarily at its usage in business-toconsumer markets. On-line purchasing management is increasing not only in the Czech Republic but also in Europe and all over the world. The customers who think rationally use on-line shopping because of money saving, speed delivery and the possibility of product comparison. This paper presents the results of a project financed by the Czech Science Foundation P403/11/ P175: The factors influencing customers’ on-line behaviour in e-commerce environment on B2C and B2B markets in the Czech Republic. 89 % of respondents use e-shops for buying products in the Czech Republic. 32 % of them use the Internet for regular purchases and 57 % of them irregularly. 11 % of respondents have not used e-shops yet.

  12. Administering Spatial and Cognitive Instruments In-class and On-line: Are These Equivalent?

    Science.gov (United States)

    Williamson, Kenneth C.; Williamson, Vickie M.; Hinze, Scott R.

    2017-02-01

    Standardized, well-established paper-and-pencil tests, which measure spatial abilities or which measure reasoning abilities, have long been found to be predictive of success in the STEM (science, technology, engineering, and mathematics) fields. Instructors can use these tests for prediction of success and to inform instruction. A comparative administration of spatial visualization and cognitive reasoning tests, between in-class (proctored paper and pencil) and on-line (unproctored Internet) ( N = 457), was used to investigate and to determine whether the differing instrument formats yielded equal measures of spatial ability and reasoning ability in large first-semester general chemistry sections. Although some gender differences were found, findings suggest that some differences across administration formats, but that on-line administration had similar properties of predicting chemistry performance as the in-class version. Therefore, on-line administration is a viable option for instructors to consider especially when dealing with large classes.

  13. Research on the Influence of Perceived Risk in Consumer On-line Purchasing Decision

    Science.gov (United States)

    Hong, Zhao; Yi, Li

    Perceived risk is an important factor that affects consumer's on-line shopping purchasing decision, through the perceived theories the consumer can know clearly which step owns higher risk in the whole shopping process, then learn how to prevent it, this process also strengthen the consumer confidence, thus lowering to know that the risk adjudicate to the feeling, so the essay has important and realistic meaning for further expand the electronic commerce. At first, investigate, collect, tidy up, analyze the questionnaire information, and thus get the primary data. Finally try to find out the influence of perceived risk to each stage of purchasing decision during consumer on-line shopping process with data and personal analytical. The paper is a complement to the local and existing perceived theories. The result of the study manifests that, the order of main perceived risks which felt by consumer during on-line shopping process are as follow: financial risk, the performance risk and service risk.

  14. Process Analytical Technology and On-Line Spectroscopic Measurements of Chemical Meat Quality

    DEFF Research Database (Denmark)

    Sørensen, Klavs Martin

    This thesis deals with process analytical technology and how it can be implemented in the meat industry through on-line grading of chemical meat quality. The focus will be on two applications, namely the rapid quality control of fat quality and the development of a method for on-line detection...... of boar taint. The chemical makeup of fat has a large effect on meat cut quality. Fat quality has traditionally been determined by methylation of a tissue sample followed by chromatography on a GC-MS system, elucidating the composition of the individual fatty acids. As this procedure typically takes far...... on surgical castration will be in effect starting 2018. With the ban, the risk of meat products with the malodorous taint reaching the consumer is highly increased, and thus, detection of boar taint is a necessity. No current on-line detection system is available; the only alternative is chemical extraction...

  15. Force-reflecting teleoperation of robots based on on-line correction of a virtual model

    Institute of Scientific and Technical Information of China (English)

    LIU Wei; SONG Aiguo; LI Huijun

    2007-01-01

    Virtual reality is an effective method to eliminate the influence of time delay.However,it depends on the precision of the virtual model.In this paper,we introduce a method that corrects the virtual model on-line to establish a more precise model.The geometric errors of the virtual model were corrected on-line by overlapping the graphics over the images and also by syncretizing the position and force information from the remote.Then the sliding average least squares (SALS)method was adopted to determine the mass,damp,and stiffness of the remote environment and use this information to amend the dynamic model of the environment.Experimental results demonstrate that the on-line correction method we proposed can effectively reduce the impact caused by time delay,and improve the operational performance of the teleoperation system.

  16. Administering Spatial and Cognitive Instruments In-class and On-line: Are These Equivalent?

    Science.gov (United States)

    Williamson, Kenneth C.; Williamson, Vickie M.; Hinze, Scott R.

    2016-08-01

    Standardized, well-established paper-and-pencil tests, which measure spatial abilities or which measure reasoning abilities, have long been found to be predictive of success in the STEM (science, technology, engineering, and mathematics) fields. Instructors can use these tests for prediction of success and to inform instruction. A comparative administration of spatial visualization and cognitive reasoning tests, between in-class (proctored paper and pencil) and on-line (unproctored Internet) (N = 457), was used to investigate and to determine whether the differing instrument formats yielded equal measures of spatial ability and reasoning ability in large first-semester general chemistry sections. Although some gender differences were found, findings suggest that some differences across administration formats, but that on-line administration had similar properties of predicting chemistry performance as the in-class version. Therefore, on-line administration is a viable option for instructors to consider especially when dealing with large classes.

  17. PF-OLA: A High-Performance Framework for Parallel On-Line Aggregation

    CERN Document Server

    Qin, Chengjie

    2012-01-01

    On-line aggregation provides estimates to the final result of a computation during the actual processing. The user can stop the computation as soon as the estimate is accurate enough, typically early in the execution. This allows for the interactive data exploration of the largest datasets. In this paper we introduce the first framework for parallel on-line aggregation in which the estimation does not incur any overhead on top of the actual execution. We define a generic interface to express any estimation model that abstracts completely the execution details. We design a novel estimator specifically targeted at parallel on- line aggregation. When executed by the framework over an 8TB TPC-H instance, the estimator provides accurate confidence bounds early in the execution even when the cardinality of the final result is seven orders of magnitude smaller than the dataset size and without incurring any overhead.

  18. On-line interprofessional learning: introducing constructivism through enquiry-based learning and peer review.

    Science.gov (United States)

    Hughes, Matthew; Ventura, Susie; Dando, Mark

    2004-08-01

    Interest in on-line methods of learning has accelerated in recent years. There has also been an interest in developing student-centred approaches to learning and interprofessional education. This paper illustrates the issues in designing a large (more than 700 students), on-line, inter-professional module for third year, undergraduate students drawn from nine professional healthcare courses and from four campus sites. It uses an enquiry-based learning approach. The learning theories of Piaget, Vygotsky and Schön are integrated with the on-line frameworks of Salmon and Collis et al., together with conclusions drawn from the literature and our own experiences, to produce a design that encourages students to learn through participation, re-iteration, peer-review and reflection. Consideration is given to improving student motivation and attitudes towards change, both in the design and the delivery of the module.

  19. Proposing national identification number on dental prostheses as universal personal identification code - A revolution in forensic odontology.

    Science.gov (United States)

    Baad, Rajendra K; Belgaumi, Uzma; Vibhute, Nupura; Kadashetti, Vidya; Chandrappa, Pramod Redder; Gugwad, Sushma

    2015-01-01

    The proper identification of a decedent is not only important for humanitarian and emotional reasons, but also for legal and administrative purposes. During the reconstructive identification process, all necessary information is gathered from the unknown body of the victim and hence that an objective reconstructed profile can be established. Denture marking systems are being used in various situations, and a number of direct and indirect methods are reported. We propose that national identification numbers be incorporated in all removable and fixed prostheses, so as to adopt a single and definitive universal personal identification code with the aim of achieving a uniform, standardized, easy, and fast identification method worldwide for forensic identification.

  20. Treatment of hepatic encephalopathy by on-line hemodiafiltration: a case series study

    Directory of Open Access Journals (Sweden)

    Sugiyama Mitsugi

    2010-05-01

    Full Text Available Abstract Background It is thought that a good survival rate of patients with acute liver failure can be achieved by establishing an artificial liver support system that reliably compensates liver function until the liver regenerates or a patient undergoes transplantation. We introduced a new artificial liver support system, on-line hemodiafiltration, in patients with acute liver failure. Methods This case series study was conducted from May 2001 to October 2008 at the medical intensive care unit of a tertiary care academic medical center. Seventeen consecutive patients who admitted to our hospital presenting with acute liver failure were treated with artificial liver support including daily on-line hemodiafiltration and plasma exchange. Results After 4.9 ± 0.7 (mean ± SD on-line hemodiafiltration sessions, 16 of 17 (94.1% patients completely recovered from hepatic encephalopathy and maintained consciousness for 16.4 ± 3.4 (7-55 days until discontinuation of artificial liver support (a total of 14.4 ± 2.6 [6-47] on-line hemodiafiltration sessions. Significant correlation was observed between the degree of encephalopathy and number of sessions of on-line HDF required for recovery of consciousness. Of the 16 patients who recovered consciousness, 7 fully recovered and returned to society with no cognitive sequelae, 3 died of complications of acute liver failure except brain edema, and the remaining 6 were candidates for liver transplantation; 2 of them received living-related liver transplantation but 4 died without transplantation after discontinuation of therapy. Conclusions On-line hemodiafiltration was effective in patients with acute liver failure, and consciousness was maintained for the duration of artificial liver support, even in those in whom it was considered that hepatic function was completely abolished.