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  1. Structural Factors Affecting Health Examination Behavioral Intention

    National Research Council Canada - National Science Library

    Huang, Hui-Ting; Kuo, Yu-Ming; Wang, Shiang-Ru; Wang, Chia-Fen; Tsai, Chung-Hung

    2016-01-01

    .... Here, we used the health belief model as a foundation and integrated social psychological factors and investigated the factors influencing health examination behavioral intention among the public in Taiwan...

  2. What is the impact of obtaining medical clearance to participate in a randomised controlled trial examining a physical activity intervention on the socio-demographic and risk factor profiles of included participants?

    Science.gov (United States)

    Duncan, Mitch J; Rosenkranz, Richard R; Vandelanotte, Corneel; Caperchione, Cristina M; Rebar, Amanda L; Maeder, Anthony J; Tague, Rhys; Savage, Trevor N; van Itallie, Anetta; Mummery, W Kerry; Kolt, Gregory S

    2016-12-07

    Requiring individuals to obtain medical clearance to exercise prior to participation in physical activity interventions is common. The impact this has on the socio-demographic characteristic profiles of participants who end up participating in the intervention is not clear. As part of the multi-component eligibility screening for inclusion in a three-arm randomised controlled trial examining the efficacy of a web-based physical activity intervention, individuals interested in participating were required to complete the Physical Activity Readiness Questionnaire (PAR-Q). The PAR-Q identified individuals as having lower or higher risk. Higher-risk individuals were required to obtain medical exercise clearance prior to enrolment. Comparisons of the socio-demographic characteristics of the lower- and higher-risk individuals were performed using t tests and chi-square tests (p = 0.05). A total of 1244 individuals expressed interest in participating, and 432 were enrolled without needing to undergo further screening. Of the 251 individuals required to obtain medical clearance, 148 received clearance, 15 did not receive clearance and 88 did not return any form of clearance. A total of 105 individuals were enrolled after obtaining clearance, and the most frequent reason for being required to seek clearance was for using blood pressure/heart condition medication. Higher-risk individuals were significantly older, had a higher body mass index and engaged in more sedentary behaviour than lower-risk individuals. Use of more inclusive participant screening protocols that maintain high levels of participant safety are encouraged. Allowing individuals to obtain medical clearance to participate can result in including a more diverse population likely to benefit most from participation. Australian New Zealand Clinical Trials Registry ( ACTRN12611000157976 ). Registered on 9 February 2011.

  3. Structural Factors Affecting Health Examination Behavioral Intention.

    Science.gov (United States)

    Huang, Hui-Ting; Kuo, Yu-Ming; Wang, Shiang-Ru; Wang, Chia-Fen; Tsai, Chung-Hung

    2016-04-01

    Disease screening instruments used for secondary prevention can facilitate early determination and treatment of pathogenic factors, effectively reducing disease incidence, mortality rates, and health complications. Therefore, people should be encouraged to receive health examinations for discovering potential pathogenic factors before symptoms occur. Here, we used the health belief model as a foundation and integrated social psychological factors and investigated the factors influencing health examination behavioral intention among the public in Taiwan. In total, 388 effective questionnaires were analyzed through structural model analysis. Consequently, this study yielded four crucial findings: (1) The established extended health belief model could effectively predict health examination behavioral intention; (2) Self-efficacy was the factor that most strongly influenced health examination behavioral intention, followed by health knowledge; (3) Self-efficacy substantially influenced perceived benefits and perceived barriers; (4) Health knowledge and social support indirectly influenced health examination behavioral intention. The preceding results can effectively increase the acceptance and use of health examination services among the public, thereby facilitating early diagnosis and treatment and ultimately reducing disease and mortality rates.

  4. Factors of Students Participating in Online Examination

    Directory of Open Access Journals (Sweden)

    Sugilar Sugilar

    2016-05-01

    Full Text Available The purpose of the study is to discover determinant factors of students' participation in online examination based on expectancy-value theory. The method used was group comparison between the groups of participating and nonparticipating students. The results showed that the following factors differentiated the two groups, i.e.: (1 self efficacy in using computers (t=12.81, p<0.01, (2 perceived of easiness in operating an online examination (t=9.51, p<0.01, (3 perceived of the importance of online examination (t=5.58, t<0.01, (4 intrinsic value of online examination (t=10.58, p<001, and (5 cost of online examination (t=-2.05, p=0.029. In addition, the following students' personal factors were also compared and the results were (1 age (t=-2.01, p=0.46, (2 grade point average (t=-5.546, 0<0.01, (3 sex (x2=28.51, p<0.01, and (4 marital status (x2=6.50, p=0.011. The results concluded that the expectancy and value theory was useful for explaining and predicting students' participation in online examinations.

  5. Examining Factors Predicting Students' Digital Competence

    Science.gov (United States)

    Hatlevik, Ove Edvard; Guðmundsdóttir, Gréta Björk; Loi, Massimo

    2015-01-01

    The purpose of this study was to examine factors predicting lower secondary school students' digital competence and to explore differences between students when it comes to digital competence. Results from a digital competence test and survey in lower secondary school will be presented. It is important to learn more about and investigate what…

  6. Examining different factors in effectiveness of advertisement

    Directory of Open Access Journals (Sweden)

    Seyed Gholamreza Jalali Naini

    2012-04-01

    Full Text Available This paper aims to study the effects of different factors on advertising by examining the simultaneous effects of exposure to the advertisement, type of the media, creativity in advertisements and being informative. Using data collected from one of the chain supermarkets of Tehran called “Shahrvand”; the analysis focuses on the effectiveness of four independent variables and impact of customers’ needs on encouraging consumers to purchase. The results elucidate a relationship among these four variables with encouraging people to purchase. Using creativity in advertisements, however dominate the effects on this issue. The marketing and advertisement environment are dynamic and the paper concentrates only on some of the more effective factors. Producers might be more successful in choosing the best way to promote their goods and services by following the proposed model. This paper puts four effective factors together and investigates their impact on advertisement, which was not done by any other previous papers. Unlike other studies, this paper examines the role of customer needs together with four other elements on advertisement effectiveness.

  7. Examining Factors That Affect Students' Knowledge Sharing within Virtual Teams

    Science.gov (United States)

    He, Jinxia; Gunter, Glenda

    2015-01-01

    The purpose of this study was to examine factors that might impact student knowledge sharing within virtual teams through online discussion boards. These factors include: trust, mutual influence, conflict, leadership, and cohesion. A path model was developed to determine whether relationships exist among knowledge sharing from asynchronous group…

  8. Examinations of factors influencing toe grip strength.

    Science.gov (United States)

    Soma, Masayuki; Murata, Shin; Kai, Yoshihiro; Nakae, Hideyuki; Satou, Yousuke; Murata, Jun; Miyazaki, Junya

    2016-11-01

    [Purpose] This study examined the relationship between toe grip strength and its associated factors by focusing on factors that were suggested to have a relationship with toe grip strength in previous studies, aiming to clarify the factors influencing the toe grip strength of healthy women. [Subjects and Methods] Twelve healthy young women were selected for this study. Their toe grip strength, angular changes in their ankle joint during toe grip, maximum voluntary contraction activities of the rectus femoris, biceps femoris, and tibialis anterior muscles, and the medial head of the gastrocnemius muscles were measured using electromyography. Their toe curl ability, foot-arch height ratio, and weight were also measured. [Results] Multiple regression analysis demonstrated that the predictors of toe grip strength in the resulting model were foot-arch height ratio and the percentage of integrated electromyography (%IEMG) of the tibialis anterior muscle, as the dependent variables. This reveals that women whose tibialis anterior muscle %IEMG values and foot-arch height ratio are high have greater %IEMG values have greater toe grip strength. [Conclusion] These findings suggest a significant relationship between foot-arch height ratio and toe grip strength, with a reciprocal interaction. These findings further indicate that the risk of falls by the elderly could be decreased if toe grip strength were enhanced, by increasing the height of a low foot-arch with the help of an inserted insole.

  9. Examining Factors Predicting Students’ Digital Competence

    Directory of Open Access Journals (Sweden)

    Ove Edvard Hatlevik

    2015-02-01

    Full Text Available The purpose of this study was to examine factors predicting lower secondary school students’ digital competence and to explore differences between students when it comes to digital competence. Results from a digital competence test and survey in lower secondary school will be presented. It is important to learn more about and investigate what characterizes students’ digital competence. A sample of 852 ninth-grade Norwegian students from 38 schools participated in the study. The students answered a 26 item multiple-choice digital competence test and a self-report questionnaire about family background, motivation, and previous grades. Structural equation modeling was used to test a model of the hypothesised relationship between family background, mastery orientation, previous achievements, and digital competence. The results indicate variation in digital competence among the ninth-graders. Further, analyses showed that students’ conditions at home, i.e., language integration and cultural capital, together with mastery orientation and academic achievements predict students digital competence. This study indicates that that there is evidence of digital diversity between lower secondary students. It does not seem like the development of digital competence among the students happens automatically. Students’ family background and school performance are the most important factors. Therefore, as this study shows, it is necessary to further investigate how schools can identify students’ level of competence and to develop plans and actions for how schools can help to try to equalize differences.

  10. predisposing factors towards examination malpractice among ...

    African Journals Online (AJOL)

    Emeka Egbochuku

    Department of Psychology, Faculty of Social Sciences, ... One research ... examination malpractice; also, gender and age are no indices for examination ... schools and it is expected that they instil a positive approach to .... interaction in.

  11. Assessment of diagnostic skills in specialist examinations should include lessons learnt from misdiagnosis.

    Directory of Open Access Journals (Sweden)

    Ehud Zamir

    Full Text Available BACKGROUND: Poor authenticity in high stake clinical exams adversely effects validity. We propose including known misleading diagnostic factors and contextual biases in the assessment of diagnostic skills amongst advanced specialty trainees. We hypothesise that this strategy offers a more realistic and critical assessment of diagnostic skill than strategies in which candidates are presented with directive, bias free information, allowing for assumptions which cannot be made in real life. METHODS: Eleven patient based practice clinical exam stations were presented to nine advanced ophthalmology trainees. Four patients had a history of misdiagnosis or near misdiagnosis of key ophthalmic findings, presumed to result from identifiable biases and misleading information. In those four stations, candidates were presented with authentic, file based information and were asked authentic questions, similar to those with which the patients presented. If the candidates were unsuccessful in identifying key findings, the questions were converted into directive questions about the same key findings (i.e. "examine the patient's eyelids, what is your diagnosis?", and the candidates re-assessed the patient and re-answered. RESULTS: Ninety-eight doctor-patient encounters took place. Of those, 35 encounters were analysed for the purpose of this study. In 63% of those encounters, key findings were missed when the question included authentic biases or misleading background information, but rephrasing the question to a directive exam format led to their correct identification (Fail converted to pass. Key findings were detected despite contextual biases or misleading background information in only 23% of encounters. In 14% the findings were missed with either question phrasing. CONCLUSIONS: Presentation authentic questions provide a more realistic and less forgiving measure of diagnostic skills than directive exam questions. Given the prevalence of diagnostic errors and

  12. Risk Factors for Breast Cancer, Including Occupational Exposures

    Directory of Open Access Journals (Sweden)

    Elisabete Weiderpass

    2011-03-01

    Full Text Available The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to humans. These evaluations are published as a series of Monographs (www.iarc.fr. For breast cancer the following substances have been classified as “carcinogenic to humans” (Group 1: alcoholic beverages, exposure to diethylstilbestrol, estrogen-progestogen contraceptives, estrogen-progestogen hormone replacement therapy and exposure to X-radiation and gamma-radiation (in special populations such as atomic bomb survivors, medical patients, and in-utero exposure. Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. The classification “probably carcinogenic to humans” (Group 2A includes estrogen hormone replacement therapy, tobacco smoking, and shift work involving circadian disruption, including work as a flight attendant. If the association between shift work and breast cancer, the most common female cancer, is confirmed, shift work could become the leading cause of occupational cancer in women.

  13. Risk factors for breast cancer, including occupational exposures.

    Science.gov (United States)

    Weiderpass, Elisabete; Meo, Margrethe; Vainio, Harri

    2011-03-01

    The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to humans. These evaluations are published as a series of Monographs (www.iarc.fr). For breast cancer the following substances have been classified as "carcinogenic to humans" (Group 1): alcoholic beverages, exposure to diethylstilbestrol, estrogen-progestogen contraceptives, estrogen-progestogen hormone replacement therapy and exposure to X-radiation and gamma-radiation (in special populations such as atomic bomb survivors, medical patients, and in-utero exposure). Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. The classification "probably carcinogenic to humans" (Group 2A) includes estrogen hormone replacement therapy, tobacco smoking, and shift work involving circadian disruption, including work as a flight attendant. If the association between shift work and breast cancer, the most common female cancer, is confirmed, shift work could become the leading cause of occupational cancer in women.

  14. Examining the Language Factor in Mathematics Assessments

    Science.gov (United States)

    Kan, Adnan; Bulut, Okan

    2015-01-01

    This study investigates whether word problems and mathematically expressed items can be used interchangeably regardless of their linguistic complexities. A sample of sixth grade students was given two forms of a mathematics assessment. The first form included mathematics items with mathematical terms, expressions, and equations whereas the second…

  15. Perinatal risk factors including malformation; Perinatale Risikofaktoren einschliesslich Fehlbildungen

    Energy Technology Data Exchange (ETDEWEB)

    Brachner, A.; Grosche, B.

    1991-10-01

    The study gives a survey of the factors most frequently mentioned in the literature as factors likely to adversely affect a pregnancy. One essential aspect is the discussion of those factors that can be counted among the causes of malformations, as among others, prenatal radiation exposure. The study prepared within the framework of the research project `Radiobiological environmental monitoring in Bavaria` is intended to serve as a basis for a retrospective and prospective evaluation of infant mortality, perinatal conditions and occurrence of malformations in Bavaria, with the principal idea of drawing up an environment - related health survey. The study therefore, in addition to ionizing radiation also takes into account other detectable risks within the ecologic context, as e.g. industrial installations, refuse incineration plants or waste dumps, or urbanity. (orig./MG). [Deutsch] In der vorliegenden Arbeit wird ein Ueberblick ueber die haeufigsten in der Literatur beschriebenen Faktoren, die einen unguenstigen Einfluss auf den Schwangerschaftsverlauf ausueben koennen, gegeben. Ein Hauptgewicht liegt dabei auf der Beschreibung von solchen Faktoren, die mit der Induktion von Fehlbildungen in Zusammenhang gebracht werden koennen, so unter anderem auch der praenatalen Strahlenexposition. Diese Arbeit, die im Rahmen des Forschungsvorhabens `Strahlenbiologisches Umweltmonitoring Bayern` angefertigt wurde, bildet die Grundlage einer im Sinne einer umweltbezogenen Gesundheitsberichterstattung retro- bzw. prospektiv angelegten Auswertung der Saeuglingssterblichkeit, des Perinatalgeschehens und der Fehlbildungshaeufigkeit in Bayern, wobei neben der ionisierenden Strahlung als Risikofaktor auch andere im Rahmen einer oekologischen Studie erfassbare Risiken, wie beispielsweise Industrieansiedlungen, Muellverbrennungsanlagen und -deponien oder Urbanitaet beruecksichtigt werden sollen. (orig./MG).

  16. Postnatal depression - an examination of psychosocial factors | Mills ...

    African Journals Online (AJOL)

    Postnatal depression - an examination of psychosocial factors. ... South African Medical Journal ... pregnancy, complications after birth, marital relations, relationship with their own mothers, social support and preparation for motherhood.

  17. Examining the factor structure of the Multiple Sclerosis Impact Scale.

    Science.gov (United States)

    Fitzgerald, Shawn M; Li, Jian; Rumrill, Phillip D; Merchant, William; Bishop, Malachy

    2014-01-01

    The purpose of this study was to investigate the factor structure of the Multiple Sclerosis Impact Scale (MSIS-29) to assess its suitability for modeling the impact of MS on a nation-wide sample of individuals from the United States. Investigators completed a Confirmatory Factor Analysis (CFA) to examine the two-factor structure proposed by Hobart et al. [17]. Although the original MSIS-29 factor structure did not fit the data exactly, the hypothesized two-factor model was partially supported in the current data. Implications for future instrument development and rehabilitation practice are discussed.

  18. Examination of equine glandular stomach lesions for bacteria, including Helicobacter spp by fluorescence in situ hybridisation

    DEFF Research Database (Denmark)

    husted, Louise; Jensen, Tim Kåre; Olsen, Susanne N.;

    2010-01-01

    Background: The equine glandular stomach is commonly affected by erosion and ulceration. The aim of this study was to assess whether bacteria, including Helicobacter, could be involved in the aetiology of gastric glandular lesions seen in horses. Results: Stomach lesions, as well as normal...... by cloning and sequencing. Mucosal lesions were found in 36/63 stomachs and included hyperplastic rugae, polypoid structures and focal erosions. None of the samples were tested positive for urease activity or for FISH using the Helicobacter genus specific probe. In samples of lesions, as well as normal...... faecium. The Enterococcus were found colonising the mucosal surface, while E. fergusonii organisms were also demonstrated intraepithelial. Conclusion: Gastric Helicobacter spp. could not be verified as being involved in lesions of the glandular stomach of the horse. Since E. fergusonii has been described...

  19. Examination of equine glandular stomach lesions for bacteria, including Helicobacter spp by fluorescence in situ hybridisation

    DEFF Research Database (Denmark)

    husted, Louise; Jensen, Tim Kåre; Olsen, Susanne N.

    2010-01-01

    Background: The equine glandular stomach is commonly affected by erosion and ulceration. The aim of this study was to assess whether bacteria, including Helicobacter, could be involved in the aetiology of gastric glandular lesions seen in horses. Results: Stomach lesions, as well as normal...... by cloning and sequencing. Mucosal lesions were found in 36/63 stomachs and included hyperplastic rugae, polypoid structures and focal erosions. None of the samples were tested positive for urease activity or for FISH using the Helicobacter genus specific probe. In samples of lesions, as well as normal...... faecium. The Enterococcus were found colonising the mucosal surface, while E. fergusonii organisms were also demonstrated intraepithelial. Conclusion: Gastric Helicobacter spp. could not be verified as being involved in lesions of the glandular stomach of the horse. Since E. fergusonii has been described...

  20. Examination of equine glandular stomach lesions for bacteria, including Helicobacter spp by fluorescence in situ hybridisation

    Directory of Open Access Journals (Sweden)

    Olsen Susanne N

    2010-03-01

    Full Text Available Abstract Background The equine glandular stomach is commonly affected by erosion and ulceration. The aim of this study was to assess whether bacteria, including Helicobacter, could be involved in the aetiology of gastric glandular lesions seen in horses. Results Stomach lesions, as well as normal appearing mucosa were obtained from horses slaughtered for human consumption. All samples were tested for urease activity using the Pyloritek® assay, while mucosal bacterial content was evaluated using Fluorescence In Situ Hybridisation. In selected sub samples, bacteria characterisation was pursued further by cloning and sequencing. Mucosal lesions were found in 36/63 stomachs and included hyperplastic rugae, polypoid structures and focal erosions. None of the samples were tested positive for urease activity or for FISH using the Helicobacter genus specific probe. In samples of lesions, as well as normal samples, clones with 99% similarities to Lactobacillus salivarius and Sarcina ventriculi were found. Escherichia like bacterium clones and Enterococcus clones were demonstrated in one focal erosion. Based on a phylogenetic tree these clones had 100% similarity to Escherichia fergusonii and Enterococcus faecium. The Enterococcus were found colonising the mucosal surface, while E. fergusonii organisms were also demonstrated intraepithelial. Conclusion Gastric Helicobacter spp. could not be verified as being involved in lesions of the glandular stomach of the horse. Since E. fergusonii has been described as an emerging pathogen in both humans and animals, the finding of this bacterium in gastric erosion warrants further clarification to whether gastric infection with this type bacterium is important for horses.

  1. Re-examining Sunspot Tilt Angle to Include Anti-Hale Statistics

    CERN Document Server

    McClintock, Bruce H; Li, Jing

    2014-01-01

    Sunspot groups and bipolar magnetic regions (BMRs) serve as an observational diagnostic of the solar cycle. We use Debrecen Photohelographic Data (DPD) from 1974-2014 that determined sunspot tilt angles from daily white light observations, and data provided by Li & Ulrich that determined sunspot magnetic tilt angle using Mount Wilson magnetograms from 1974-2012. The magnetograms allowed for BMR tilt angles that were anti-Hale in configuration, so tilt values ranged from 0 to 360{\\deg} rather than the more common $\\pm$ 90{\\deg}. We explore the visual representation of magnetic tilt angles on a traditional butterfly diagram by plotting the mean area-weighted latitude of umbral activity in each bipolar sunspot group, including tilt information. The large scatter of tilt angles over the course of a single cycle and hemisphere prevents Joy's law from being visually identified in the tilt-butterfly diagram without further binning. The average latitude of anti-Hale regions does not differ from the average latitu...

  2. RE-EXAMINING SUNSPOT TILT ANGLE TO INCLUDE ANTI-HALE STATISTICS

    Energy Technology Data Exchange (ETDEWEB)

    McClintock, B. H. [University of Southern Queensland, Toowoomba, 4350 (Australia); Norton, A. A. [HEPL, Stanford University, Palo Alto, CA 94305 (United States); Li, J., E-mail: u1049686@umail.usq.edu.au, E-mail: aanorton@stanford.edu, E-mail: jli@igpp.ucla.edu [Department of Earth, Planetary, and Space Sciences, University of California at Los Angeles, Los Angeles, CA 90095 (United States)

    2014-12-20

    Sunspot groups and bipolar magnetic regions (BMRs) serve as an observational diagnostic of the solar cycle. We use Debrecen Photohelographic Data (DPD) from 1974-2014 that determined sunspot tilt angles from daily white light observations, and data provided by Li and Ulrich that determined sunspot magnetic tilt angle using Mount Wilson magnetograms from 1974-2012. The magnetograms allowed for BMR tilt angles that were anti-Hale in configuration, so tilt values ranged from 0 to 360° rather than the more common ±90°. We explore the visual representation of magnetic tilt angles on a traditional butterfly diagram by plotting the mean area-weighted latitude of umbral activity in each bipolar sunspot group, including tilt information. The large scatter of tilt angles over the course of a single cycle and hemisphere prevents Joy's law from being visually identified in the tilt-butterfly diagram without further binning. The average latitude of anti-Hale regions does not differ from the average latitude of all regions in both hemispheres. The distribution of anti-Hale sunspot tilt angles are broadly distributed between 0 and 360° with a weak preference for east-west alignment 180° from their expected Joy's law angle. The anti-Hale sunspots display a log-normal size distribution similar to that of all sunspots, indicating no preferred size for anti-Hale sunspots. We report that 8.4% ± 0.8% of all bipolar sunspot regions are misclassified as Hale in traditional catalogs. This percentage is slightly higher for groups within 5° of the equator due to the misalignment of the magnetic and heliographic equators.

  3. Juvenile Offender Recidivism: An Examination of Risk Factors

    Science.gov (United States)

    Calley, Nancy G.

    2012-01-01

    One hundred and seventy three male juvenile offenders were followed two years postrelease from a residential treatment facility to assess recidivism and factors related to recidivism. The overall recidivism rate was 23.9%. Logistic regression with stepwise and backward variable selection methods was used to examine the relationship between…

  4. Behavioral factors to include in guidelines for lifelong oral healthiness: an observational study in Japanese adults

    Directory of Open Access Journals (Sweden)

    Shimozato Miho

    2006-12-01

    Full Text Available Abstract Background The aim of this study was to determine which behavioral factors to include in guidelines for the Japanese public to achieve an acceptable level of oral healthiness. The objective was to determine the relationship between oral health related behaviors and symptoms related to oral disease and tooth loss in a Japanese adult community. Methods Oral health status and lifestyle were investigated in 777 people aged 20 years and older (390 men and 387 women. Subjects were asked to complete a postal questionnaire concerning past diet and lifestyle. The completed questionnaires were collected when they had health examinations. The 15 questions included their preference for sweets, how many between-meal snacks they usually had per day, smoking and drinking habits, presence of oral symptoms, and attitudes towards dental visits. Participants were asked about their behaviors at different stages of their life. The oral health examinations included examination of the oral cavity and teeth performed by dentists using WHO criteria. Odds ratios were calculated for all subjects, all 10 year age groups, and for subjects 30 years or older, 40 years or older, 50 years or older, and 60 years or older. Results Frequency of tooth brushing (OR = 3.98, having your own toothbrush (OR = 2.11, smoking (OR = 2.71 and bleeding gums (OR = 2.03 were significantly associated with number of retained teeth in males. Frequency of between-meal snacks was strongly associated with number of retained teeth in females (OR = 4.67. Having some hobbies (OR = 2.97, having a family dentist (OR = 2.34 and consulting a dentist as soon as symptoms occurred (OR = 1.74 were significantly associated with number of retained teeth in females. Factors that were significantly associated with tooth loss in both males and females included alcohol consumption (OR = 11.96, males, OR = 3.83, females, swollen gums (OR = 1.93, males, OR = 3.04, females and toothache (OR = 3.39, males, OR

  5. An empirical examination of the factor structure of compassion

    Science.gov (United States)

    Gu, Jenny; Cavanagh, Kate; Baer, Ruth

    2017-01-01

    Compassion has long been regarded as a core part of our humanity by contemplative traditions, and in recent years, it has received growing research interest. Following a recent review of existing conceptualisations, compassion has been defined as consisting of the following five elements: 1) recognising suffering, 2) understanding the universality of suffering in human experience, 3) feeling moved by the person suffering and emotionally connecting with their distress, 4) tolerating uncomfortable feelings aroused (e.g., fear, distress) so that we remain open to and accepting of the person suffering, and 5) acting or being motivated to act to alleviate suffering. As a prerequisite to developing a high quality compassion measure and furthering research in this field, the current study empirically investigated the factor structure of the five-element definition using a combination of existing and newly generated self-report items. This study consisted of three stages: a systematic consultation with experts to review items from existing self-report measures of compassion and generate additional items (Stage 1), exploratory factor analysis of items gathered from Stage 1 to identify the underlying structure of compassion (Stage 2), and confirmatory factor analysis to validate the identified factor structure (Stage 3). Findings showed preliminary empirical support for a five-factor structure of compassion consistent with the five-element definition. However, findings indicated that the ‘tolerating’ factor may be problematic and not a core aspect of compassion. This possibility requires further empirical testing. Limitations with items from included measures lead us to recommend against using these items collectively to assess compassion. Instead, we call for the development of a new self-report measure of compassion, using the five-element definition to guide item generation. We recommend including newly generated ‘tolerating’ items in the initial item pool, to

  6. Examining Factors that Affect Knowledge Sharing and Students' Attitude toward Their Learning Experience within Virtual Teams

    Science.gov (United States)

    He, Jinxia

    2009-01-01

    This study examined factors that might impact student knowledge sharing within virtual teams through online discussion boards. These factors included: trust, mutual influence, conflict, leadership, and cohesion. A path model was developed to determine whether relationships exist among knowledge sharing from asynchronous group discussion and the…

  7. Macroenvironmental factors including GDP per capita and physical activity in Europe.

    Science.gov (United States)

    Cameron, Adrian J; Van Stralen, Maartje M; Kunst, Anton E; Te Velde, Saskia J; Van Lenthe, Frank J; Salmon, Jo; Brug, Johannes

    2013-02-01

    Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. We examined the relationship between country-level data on macroenvironmental factors (gross domestic product (GDP) per capita, public sector expenditure on health, percentage living in urban areas, and cars per 1000 population) with country-level physical activity prevalence obtained from previous pan-European studies. Studies that assessed leisuretime physical activity (n = 3 studies including 27 countries in adults, n = 2 studies including 28 countries in children) and total physical activity (n = 3 studies in adults including 16 countries) were analyzed separately as were studies among adults and children. Strong and consistent positive correlations were observed between country prevalence of leisure-time physical activity and country GDP per capita in adults (average r = 0.70; all studies, P G 0.05). In multivariate analysis, country prevalence of leisure-time physical activity among adults remained associated with country GDP per capita (two of three studies) but not urbanization or educational attainment. Among school-age populations, no association was found between country GDP per capita and country prevalence of leisure-time physical activity. In those studies that assessed total physical activity (which also includes occupational and transport physical activity), no association with country GDP per capita was observed. Clear differences in national leisure-time physical activity levels throughout Europe may be a consequence of economic development. Lack of economic development of some countries in Europe may make increasing leisure-time physical activity more difficult. Further examination of the link between country GDP per capita and national physical activity levels (across

  8. Value of the small cohort study including a physical examination for minor structural defects in identifying new human teratogens.

    Science.gov (United States)

    Chambers, Christina D

    2011-03-01

    Most known human teratogens are associated with a unique or characteristic pattern of major and minor malformations and this pattern helps to establish the causal link between the teratogenic exposure and the outcome. Although traditional case-control and cohort study designs can help identify potential teratogens, there is an important role for small cohort studies that include a dysmorphological examination of exposed and unexposed infants for minor structural defects. In combination with other study design approaches, the small cohort study with a specialized physical examination fulfills a necessary function in screening for new potential teratogens and can help to better delineate the spectrum and magnitude of risk for known teratogens.

  9. The assessment of cyberstalking: an expanded examination including social networking, attachment, jealousy, and anger in relation to violence and abuse.

    Science.gov (United States)

    Strawhun, Jenna; Adams, Natasha; Huss, Matthew T

    2013-01-01

    Because the first antistalking statute was enacted in California in 1990, stalking research has been expanded immensely, yet been largely confined to exploring traditional pursuit tactics. This study instead examined the prevalence and correlates of cyberstalking behaviors while examining the phenomenon in a more inclusive manner than previous studies focusing on cyberstalking by including social networking avenues. In addition to a measure assessing cyberstalking-related behaviors, questionnaires assessing pathological aspects of personality, including attachment style, interpersonal jealousy, interpersonal violence, and anger were also provided to participants. Results indicate that, given preliminary evidence, cyberstalking-related behaviors are related to past measures of traditional stalking and cyberstalking, although prior attachment, jealousy, and violence issues within relationships are significant predictors of cyberstalking-related behaviors. In addition, unexpected gender differences emerged. For example, women admitted greater frequencies of cyberstalking perpetration than males, signaling that further research on frequency and motivation for cyberstalking among the sexes is necessary.

  10. Examining Factors Associated with Heavy Episodic Drinking Among College Undergraduates.

    Science.gov (United States)

    Scholly, Kristen; Katz, Alan R; Kehl, Lisa

    2014-04-26

    Heavy episodic drinking among college students is a serious health concern. The purpose of this study was to identify factors associated with heavy episodic drinking behaviors amongst a predominately Asian undergraduate college student population in the United States. A survey measuring alcohol use behaviors was completed by a random sample of 18-24 year old undergraduates during April, 2011. A multivariate logistic regression analysis was conducted to determine factors associated with students' heavy episodic drinking behavior. Independent factors associated with heavy episodic drinking included living on campus, ethnicity, perceived drinking behavior among peers, and a belief that alcohol is a central part of one's social life. Heavy episodic drinking was also associated with poor academic performance. Campus-wide educational strategies to reduce heavy episodic drinking among college undergraduates should incorporate accurate information regarding alcohol use norms to correct students' perceived over estimation of their peers alcohol consumption rates and the under estimation of students protective alcohol use behaviors. These efforts should focus in on-campus residence halls where a higher occurrence of heavy episodic drinking is often found.

  11. Examining factors associated with heavy episodic drinking among college undergraduates

    Directory of Open Access Journals (Sweden)

    Kristen Scholly

    2014-08-01

    Full Text Available Heavy episodic drinking among college students is a serious health concern. The purpose of this study was to identify factors associated with heavy episodic drinking behaviors amongst a predominately Asian undergraduate college student population in the United States. A survey measuring alcohol use behaviors was completed by a random sample of 18-24 year old undergraduates during April, 2011. A multivariate logistic regression analysis was conducted to determine factors associated with students’ heavy episodic drinking behavior. Independent factors associated with heavy episodic drinking included living on campus, ethnicity, perceived drinking behavior among peers, and a belief that alcohol is a central part of one’s social life. Heavy episodic drinking was also associated with poor academic performance. Campus-wide educational strategies to reduce heavy episodic drinking among college undergraduates should incorporate accurate information regarding alcohol use norms to correct students’ perceived over estimation of their peers alcohol consumption rates and the under estimation of students protective alcohol use behaviors. These efforts should focus in on-campus residence halls where a higher occurrence of heavy episodic drinking is often found.

  12. Factors affecting the forensic examination of automotive lubricating oils.

    Science.gov (United States)

    Hibbard, Ryan; Goodpaster, John V; Evans, Michelle R

    2011-05-01

    Lubricating oil comparisons impact a variety of forensic investigations, including cases where oil was transferred from a suspect vehicle to the crime scene or victim. In this study, high-temperature gas chromatography/mass spectrometry was used to examine the influence of oil mixtures and oil changes over time on the comparison of known and questioned lubricating oils. Varying concentrations of oil mixtures were prepared and showed the potential for identifying individual components. Motor oils from 18 automobiles monitored over a 2-month period did not demonstrate significant changes in the chromatographic data. Chemometric analysis of motor oil mass spectral data provided little information regarding differentiation of, or changes in, the samples. Power steering fluid (PSF) from a naturally occurring leak collected from several locations was consistent with the PSF in the automobile's reservoir, and the PSF composition did not change over time.

  13. Resource and environmental factors should be included in economic analytical framework

    Institute of Scientific and Technical Information of China (English)

    金碚

    2009-01-01

    In the economic analysis framework,natural resources and environmental factors are included in the category of capital or land.Hence,the explanatory variables of the production function only include capital,labor and the residue term technology.Such framework may be designed for methodological reasons,but it is determined

  14. Clinical Prediction Making: Examining Influential Factors Related to Clinician Predictions of Recidivism among Juvenile Offenders

    Science.gov (United States)

    Calley, Nancy G.; Richardson, Emily M.

    2011-01-01

    This study examined factors influencing clinician predictions of recidivism for juvenile offenders, including youth age at initial juvenile justice system involvement, youth age at discharge, program completion status, clinician perception of strength of the therapeutic relationship, and clinician perception of youth commitment to treatment.…

  15. Cardiovascular risk factors encountered during medical examination in athletic children.

    Science.gov (United States)

    Cis Spoturno, Adela C; Paz-Sauquillo, María T; López-Zea, Matilde; Fernández-Rostello, Eduardo A

    2013-12-01

    Cardiovascular risk factors can predispose to cardiovascular disease in adults or lead to cardiovascular events while practicing sports. The objectives of this study were: 1) to estimate the distribution of individual cardiovascular risk factors; 2) to establish a relationship between cardiovascular risk factors in parents or grandparents and the children's clinical condition. This was a retrospective study to assess overweight, obesity and hypertension in 1021 child athletes. The family history of obesity, type 2 diabetes, ischemic heart disease, and stroke was studied. Out of the studied children, 22.1% (n= 226) were obese and 2.1% (n= 21) had hypertension. Obesity was the most common family risk factor (30%).

  16. Examining the "liberal media" claim: journalists' views on politics, economic and social policy (including health care), and media coverage.

    Science.gov (United States)

    Croteau, D

    1999-01-01

    The conservative critique of the news media rests on two general propositions: journalists hold views that are to the left of the public, and journalists frame news content in a way that accentuates these left perspectives. Previous research has revealed persuasive evidence against the latter claim, but the validity of the former claim has often been taken for granted. This research project examined the supposed left orientation of media personnel by surveying Washington-based journalists who cover national politics and/or economic policy at U.S. outlets. The findings include: (1) On select issues from corporate power and trade to Social Security and Medicare to health care and taxes, journalists are actually more conservative than the general public. (2) Journalists are mostly centrist in their political orientation. (3) The minority of journalists who do not identify with the "center" are more likely to identify with the "right" when it comes to economic issues and to identify with the "left" when it comes to social issues. (4) Journalists report that "business-oriented news outlets" and "major daily newspapers" provide the highest quality coverage of economic policy issues, while "broadcast network TV news" and "cable news services" provide the worst.

  17. Confirmatory factor analysis for the Eating Disorder Examination Questionnaire: Evidence supporting a three-factor model.

    Science.gov (United States)

    Barnes, Jennifer; Prescott, Tim; Muncer, Steven

    2012-12-01

    The purpose of this investigation was to compare the goodness-of-fit of a one factor model with the four factor model proposed by Fairburn (2008) and the three factor model proposed by Peterson and colleagues (2007) for the Eating Disorder Examination Questionnaire (EDE-Q 6.0) (Fairburn and Beglin, 1994). Using a cross-sectional design, the EDE-Q was completed by 569 adults recruited from universities and eating disorder charities in the UK. Confirmatory factor analysis (CFA) was carried out for both the student and non-student groups. CFA indicated that Peterson et al.'s (2007) three factor model was the best fit for both groups within the current data sample. Acceptable levels of internal reliability were observed and there was clear evidence for a hierarchical factor of eating disorder. The results of this study provide support for the three factor model of the EDE-Q suggested by Peterson and colleagues (2007) in that this model was appropriate for both the student and non-student sample populations. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. A Study of Factors Promoting Success in Computer Science Including Gender Differences

    Science.gov (United States)

    Cantwell Wilson, Brenda

    2002-03-01

    This study was conducted to determine factors that promote success in an introductory college computer science course and to determine what, if any, differences appear between genders on those factors. The model included math background, attribution for success/failure, self-efficacy, encouragement, comfort level in the course, work style preference, previous programming experience, previous non-programming computer experience, and gender as possible predictive factors for success in the computer science course. Subjects included 105 students enrolled in an introductory computer science course. The study revealed three predictive factors in the following order of importance: comfort level (with a positive influence), math background (with a positive influence), and attribution to luck (with a negative influence). No significant gender differences were found in these three factors. The study also revealed that both a formal class in programming (which had a positive correlation) and game playing (which had a negative correlation) were predictive of success. The study revealed a significant gender difference in game playing with males reporting more experience with playing games on the computer than females reported.

  19. A critical examination of factors that might encourage secrecy

    Science.gov (United States)

    Tough, Allen

    If a signal is detected someday from extraterrestrial intelligence, several factors might encourage complete and immediate secrecy. As a result, all data might be restricted to the receiving facility or nation instead of being shared promptly with SETI scientists around the world. Seven factors seem particularly like to encourage secrecy: (1) the belief that people may panic; (2) the fear of a negative impact on religion, science, and culture; (3) embarrassment; (4) the individual and national competitive urge; (5) avoiding a harmful premature reply; (6) a national trade or military advantage; and (7) the fear of a Trojan Horse. Three steps might alleviate the particularly difficult factors (numbers 4, 5, 6): an international treaty for immediate sharing of possible signals with SETI scientists in several other countries; implementation and frequent use of an actual network of scientists for such sharing; and further study of the possible need for partial restriction of data about the location and channel of a suspected signal.

  20. Risk factors and hospitalization costs of Dementia patients: Examining race and gender variations

    Directory of Open Access Journals (Sweden)

    Baqar Husaini

    2015-01-01

    Full Text Available Aims: To examine the variation in risk factors and hospitalization costs among four elderly dementia cohorts by race and gender. Materials and Methods: The 2008 Tennessee Hospital Discharged database was examined. The prevalence, risk factors and cost of inpatient care of dementia were examined for individuals aged 65 years and above, across the four race gender cohorts - white males (WM, black males (BM, white females (WF, and black females (BF. Results: 3.6% of patients hospitalized in 2008 had dementia. Dementia was higher among females than males, and higher among blacks than whites. Further, BF had higher prevalence of dementia than WF; similarly, BM had a higher prevalence of dementia than WM. Overall, six risk factors were associated with dementia for the entire sample including HTN, DM, CKD, CHF, COPD, and stroke. These risk factors varied slightly in predicting dementia by race and gender. Hospital costs were 14% higher among dementia patients compared to non-dementia patients. Conclusions: There exist significant race and gender disparities in prevalence of dementia. A greater degree of co-morbidity, increased duration of hospital stay, and more frequent hospitalizations, may result in a higher cost of inpatient dementia care. Aggressive management of risk factors may subsequently reduce stroke and cost of dementia care, especially in the black population. Race and gender dependent milestones for management of these risk factors should be considered.

  1. Teenage Pregnancy among Latinas: Examining Risk and Protective Factors

    Science.gov (United States)

    Dogan-Ates, Aysun; Carrion-Basham, Carla Y.

    2007-01-01

    This study investigated the role of three groups of risk and protective factors (e.g., individual, family, and extrafamilial) that are associated with teen pregnancy. Two groups of Latina adolescents (aged 15 to 19), nonpregnant/ nonparenting (NP; N = 48) and pregnant/parenting (P; N = 46), completed a demographic survey, an adolescent profile…

  2. Where's the impairment: an examination of factors that impact sustained attention following a stressor.

    Science.gov (United States)

    Banks, Jonathan B; Tartar, Jaime L; Welhaf, Matthew S

    2014-01-01

    The impact of stress on cognitive functioning has been examined across multiple domains. However, few studies investigate both physical and psychological factors that impact cognitive performance. The current study examined the impact of a physical and psychosocial stressor on sustained attention and identified factors related to sustained attention, including cortisol, salivary alpha amylase (sAA) and mind wandering. A total of 53 participants completed either the socially evaluated cold pressor task or a control task followed by the sustained attention to response task with mind wandering measures. Participants also provided saliva samples following the attention task. Results indicate the stressor task did not impact mind wandering or sustained attention but increased cortisol and sAA. Mind wandering was negatively related to sustained attention and mediated the relationship between cortisol and sustained attention. The findings highlight the importance of examining multiple sources of stress-related cognitive impairments.

  3. Learning and Study Strategies Inventory subtests and factors as predictors of National Board of Chiropractic Examiners Part 1 examination performance.

    Science.gov (United States)

    Schutz, Christine M; Dalton, Leanne; Tepe, Rodger E

    2013-01-01

    This study was designed to extend research on the relationship between chiropractic students' learning and study strategies and national board examination performance. Sixty-nine first trimester chiropractic students self-administered the Learning and Study Strategies Inventory (LASSI). Linear trends tests (for continuous variables) and Mantel-Haenszel trend tests (for categorical variables) were utilized to determine if the 10 LASSI subtests and 3 factors predicted low, medium and high levels of National Board of Chiropractic Examiners (NBCE) Part 1 scores. Multiple regression was performed to predict overall mean NBCE examination scores using the 3 LASSI factors as predictor variables. Four LASSI subtests (Anxiety, Concentration, Selecting Main Ideas, Test Strategies) and one factor (Goal Orientation) were significantly associated with NBCE examination levels. One factor (Goal Orientation) was a significant predictor of overall mean NBCE examination performance. Learning and study strategies are predictive of NBCE Part 1 examination performance in chiropractic students. The current study found LASSI subtests Anxiety, Concentration, Selecting Main Ideas, and Test Strategies, and the Goal-Orientation factor to be significant predictors of NBCE scores. The LASSI may be useful to educators in preparing students for academic success. Further research is warranted to explore the effects of learning and study strategies training on GPA and NBCE performance.

  4. TUMOR NECROSIS FACTOR-α INHIBITORS IN THE TREATMENT OF AXIAL SPONDYLOARTHRITIS, INCLUDING ANKYLOSING SPONDYLITIS

    Directory of Open Access Journals (Sweden)

    S. A. Lapshina

    2016-01-01

    Full Text Available The paper provides guidelines for the use of tumor necrosis factor-α  (TNF-α inhibitors in the treatment of patients with axial spondyloarthritis  (axSpA, including ankylosing spondylitis. It gives data on the efficacy of TNF-α inhibitors in patients with non-radiographic axSpA. By using international and Russian guidelines, the authors lay down indications for this therapy and criteria for evaluation of its efficiency and safety.

  5. Sociocultural factors associated with breast self-examination among Iranian women.

    Science.gov (United States)

    Naghibi, Seyed Abolhasan; Shojaizadeh, Davood; Montazeri, Ali; Yazdani Cherati, Jamshid

    2015-01-01

    Of the ways to fight breast cancer and reduce deaths hazard due to early detection is one of early detection programs in women's breast self- examination. Examining breast by oneself increase individuals knowledge of her breast health that helps in detecting breast cancer early. Different cultural, social, family and individual factors play roles in women's behavior about breast self- examination applying PEN-3 model in this study is to analyze factors influencing on breast self-examination. The research is a descriptive- analytical, cross-sectional type. Research community consists of women at fertility age of 20-49 in sari. Sample volume is 415 individuals and sampling method is cluster method. In this study, a 50-item questionnaire based on PEN-3 was used. Questions were answered by Likert scoring method. Questionnaire was gathered by personal presence of questioners. Data was analyzed via descriptive statistics and logistic regression methods. Based on the study findings, the most significant positive behaviors related to perceptual factors included effectiveness of disease background in family and relatives (73%), believing in breast self- examination for pursuing health (93%) and the most important negative behaviors were shyness and modesty (83.9%) and increased worry (78.9%). The most remarkable positive behaviors regarding enabling factors covered the skill to do breast examination oneself (35.2%), the availability of health and therapeutic centers (80.7%) and the most significant negative behavior was being busy and lack of time (85.3%). The most important positive behavior about nurturing factors included family consent (68.9%) and the most significant negative one was the inappropriate treatment of health and therapeutic personnel (61.8%). In this study, there is a meaningful difference between employment ages, education with PEN-3 model constituents. Since behaviors due to enabling and nurturing perceptual factors have been important in doing or not

  6. Clinical examination findings as prognostic factors in low back pain

    DEFF Research Database (Denmark)

    Hartvigsen, Lisbeth; Kongsted, Alice; Hestbaek, Lise

    2015-01-01

    BACKGROUND: There is a strong tradition of performing a clinical examination of low back pain (LBP) patients and this is generally recommended in guidelines. However, establishing a pathoanatomic diagnosis does not seem possible in most LBP patients and clinical tests may potentially be more...... been investigated in confirmatory studies and study quality is generally low. There is a need for hypothesis testing studies designed specifically to investigate the prognostic value of the clinical tests, and a need for standardization of the performance and interpretation of tests....

  7. Critical Success in E-learning: An Examination of Technological and Institutional Support Factors

    Directory of Open Access Journals (Sweden)

    Maslin Masrom

    2008-12-01

    Full Text Available In recent years, information technology (IT becomes prominent to support teaching and learning activities. IT tools allow us to create, collect, store and use the information and knowledge. E-learning was one of IT tools introduced at College of Science and Technology (CST, University Technology Malaysia (UTM Kuala Lumpur since 2001. It has enabled a paradigm shift from institutio n-centered instruction to anywhere, anytime and anybody learning models. In CST the e-learning technology was used for accessing the syllabus and course content, submitting assignments, and taking class quizzes. This paper focuses on issues relating to the e-learning critical success factors (CSFs from university students’ perspective. In this study, two main factors related to the e-learning CSFs within a university environment included technological and institutional support factors were examined. Confirmatory factor modeling approach was used to assess the criticality of the measures included in each factor. The results indicated that the most critical measures for technological factor in terms of ease of access and infrastructure are the browser efficiency, course website ease of use and computer network reliability. Meanwhile, for institutional support factor, the most critical measure is the availability of technical support or help desk.

  8. Examining perspectives on telecare: factors influencing adoption, implementation, and usage

    Directory of Open Access Journals (Sweden)

    Barrett D

    2014-12-01

    Full Text Available David Barrett,1 Jonathan Thorpe,2 Nick Goodwin3 1Faculty of Health and Social Care, 2Knowledge Exchange, University of Hull, Hull, 3International Foundation for Integrated Care, Oxford, UK Abstract: Telecare, or the use of remote care technologies to support safe and independent living, offers great potential to mitigate the challenges faced in a time of changing demographics. By supporting people to live for longer in their own home, telecare can enhance quality of life, reduce reliance on institutional care settings, and reduce costs. Despite these potential opportunities, the adoption of telecare has not been as fast or widespread as it might have been. This article discusses some of the factors acting as drivers or barriers, which have influenced adoption and impacted on implementation. The implications of the availability of such a wide range of telecare applications is explored; this diversity of choice allows for services to be tailored to the specific needs of users, but also causes a tangled web of terminology that can lead to confusion and lack of clarity. In terms of the evidence base, although evaluations of telecare services often demonstrate a high level of cost benefit and user satisfaction, primary research findings are not as positive. This paper focuses particularly on the Whole System Demonstrator, a large-scale, randomized controlled trial that raised questions about the value and cost-effectiveness of telecare. The paper also discusses the ethical, governance, and resource issues associated with telecare implementation and the organizational complexities inherent in such exciting but challenging changes to services. The policy perspective is also summarized, highlighting how much of the adoption of telecare to date has been influenced by top-down initiatives. Telecare will continue to evolve as our understanding and the technology continue to develop. This paper provides information and advice for commissioners, providers

  9. Z' factor including siRNA design quality parameter in RNAi screening experiments.

    Science.gov (United States)

    Mazur, Sławomir; Kozak, Karol

    2012-05-01

    RNA interference (RNAi) high-content screening (HCS) enables massive parallel gene silencing and is increasingly being used to reveal novel connections between genes and disease-relevant phenotypes. The application of genome-scale RNAi relies on the development of high quality HCS assays. The Z' factor statistic provides a way to evaluate whether or not screening run conditions (reagents, protocols, instrumentation, kinetics, and other conditions not directly related to the test compounds) are optimized. Z' factor, introduced by Zhang et al., ( 1) is a dimensionless value that represents both the variability and the dynamic range between two sets of sample control data. This paper describe a new extension of the Z' factor, which integrates bioinformatics RNAi non-target compounds for screening quality assessment. Currently presented Z' factor is based on positive and negative control, which may not be sufficient for RNAi experiments including oligonucleotides (oligo) with lack of knock-down. This paper proposes an algorithm which extends existing algorithm by using additional controls generetaed from on-target analysis.

  10. Revised emission factors for gas engines including start/stop emissions

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Malene; Boll Illerup, J.; Birr-Petersen, K.

    2008-06-15

    Liberalisation of the electricity market has led to Danish gas engine plants increasingly converting to the spot and regulating power markets. In order to offer regulating power, plants need to be able to start and stop the engines at the plants quickly. The liberalisation causes a considerable change of operation practice of the engines e.g. less full load operation hours /year. The project provides an inventory determining the scale of the emissions during the start and stop sequence as well as proposals for engine modifications aimed at reducing start/stop emissions. This report includes calculation of emission factors as well as an inventory of total emissions and reduction potentials. (au)

  11. The promise and challenge of including multimedia items in medical licensure examinations: some insights from an empirical trial.

    Science.gov (United States)

    Shen, Linjun; Li, Feiming; Wattleworth, Roberta; Filipetto, Frank

    2010-10-01

    The Comprehensive Osteopathic Medical Licensing Examination conducted a trial of multimedia items in the 2008-2009 Level 3 testing cycle to determine (1) if multimedia items were able to test additional elements of medical knowledge and skills and (2) how to develop effective multimedia items. Forty-four content-matched multimedia and text multiple-choice items were randomly delivered to Level 3 candidates. Logistic regression and paired-samples t tests were used for pairwise and group-level comparisons, respectively. Nine pairs showed significant differences in either difficulty or/and discrimination. Content analysis found that, if text narrations were less direct, multimedia materials could make items easier. When textbook terminologies were replaced by multimedia presentations, multimedia items could become more difficult. Moreover, a multimedia item was found not uniformly difficult for candidates at different ability levels, possibly because multimedia and text items tested different elements of a same concept. Multimedia items may be capable of measuring some constructs different from what text items can measure. Effective multimedia items with reasonable psychometric properties can be intentionally developed.

  12. Prognostic factors of infantile spasms: role of treatment options including a ketogenic diet.

    Science.gov (United States)

    Lee, Jeehun; Lee, Jun Hwa; Yu, Hee Jun; Lee, Munhyang

    2013-09-01

    The aim of this study was to provide additional evidences on prognostic factors for infantile spasms and the possible role of a ketogenic diet. A retrospective analysis was performed for patients with infantile spasms who had been followed up for more than 6months between January 2000 and July 2012 at Samsung Medical Center (Seoul, Republic of Korea). We analyzed the association between possible prognostic factors and seizure/developmental outcomes. Sixty-nine patients were included in this study and their mean follow-up duration was 52.5 (9-147) months. In the patients who had been followed up for more than 2years, 53.6% (n=30/57) remained seizure-free at the last visit. Sixty patients (86.9%) showed developmental delay at last follow-up. Forty-two patients (60.9%) became spasm-free with one or two antiepileptic drugs, one patient with epilepsy surgery for a tumor, and seven patients with a ketogenic diet after the failure of two or more antiepileptic drugs. The etiology and age of seizure onset were the significant prognostic factors. In this study, about 60% of the patients became spasm-free with vigabatrin and topiramate. Ketogenic diet increased the rate by 10% in the remaining antiepileptic drug resistant patients. However, 86.9% of the patients showed developmental delay, mostly a severe degree. Early diagnosis and prompt application of treatment options such as antiepileptic drugs, a ketogenic diet or epilepsy surgery can improve outcomes in patients with infantile spasms. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  13. Is ultrasound changing the way we understand rheumatology? Including ultrasound examination in the classification criteria of polymyalgia rheumatica and gout.

    Science.gov (United States)

    Codreanu, Catalin; Enache, Luminita

    2015-03-01

    Ultrasonography (US) is widely used in the diagnosis of rheumatic conditions, and its value for the classification criteria of rheumatic diseases has been recently suggested. According to the EULAR/ACR provisional criteria for polymyalgia rheumatica, adding US to the clinical and serological features will significantly improve the sensitivity of proposed criteria. The ability of high resolution US to detect crystalline deposits of monosodium urate in joints and soft tissues is well recognized. For the first time, the new 2014 ACR/EULAR set of proposed criteria for gout includes advanced imaging techniques for the detection of disease: US and dual-energy computed tomography. Due to low costs and affordability, use of US evaluation for patients with suspected gout will increase both specificity and sensibility of classification criteria. The recent inclusion of US in the classification criteria of various rheumatic diseases, such as PMR and gout, implies that this imaging technique is not only useful as a valued diagnostic tool for individual cases, but also on a larger scale, it will improve doctors' ability to classify diseases. Its use is thus changing our understanding of rheumatic diseases allowing further advances in research and clinical practice.

  14. Examining the Association Between the NAPLEX, Pre-NAPLEX, and Pre- and Post-admission Factors.

    Science.gov (United States)

    Chisholm-Burns, Marie A; Spivey, Christina A; Byrd, Debbie C; McDonough, Sharon L K; Phelps, Stephanie J

    2017-06-01

    Objective. To examine the relationship between the NAPLEX and Pre-NAPLEX among pharmacy graduates, as well as determine effects of pre-pharmacy, pharmacy school, and demographic variables on NAPLEX performance. Methods. A retrospective review of pharmacy graduates' NAPLEX scores, Pre-NAPLEX scores, demographics, pre-pharmacy academic performance factors, and pharmacy school academic performance factors was performed. Bivariate (eg, ANOVA, independent samples t-test) and correlational analyses were conducted, as was stepwise linear regression to examine the significance of Pre-NAPLEX score and other factors as related to NAPLEX score. Results. One hundred fifty graduates were included, with the majority being female (60.7%) and white (72%). Mean NAPLEX score was 104.7. Mean Pre-NAPLEX score was 68.6. White students had significantly higher NAPLEX scores compared to Black/African American students. NAPLEX score was correlated to Pre-NAPLEX score, race/ethnicity, PCAT composite and section scores, undergraduate overall and science GPAs, pharmacy GPA, and on-time graduation. The regression model included pharmacy GPA and Pre-NAPLEX score. Conclusion. The findings provide evidence that, although pharmacy GPA is the most critical determinant, the Pre-NAPLEX score is also a significant predictor of NAPLEX score.

  15. Fever in trauma patients: evaluation of risk factors, including traumatic brain injury.

    Science.gov (United States)

    Bengualid, Victoria; Talari, Goutham; Rubin, David; Albaeni, Aiham; Ciubotaru, Ronald L; Berger, Judith

    2015-03-01

    The role of fever in trauma patients remains unclear. Fever occurs as a response to release of cytokines and prostaglandins by white blood cells. Many factors, including trauma, can trigger release of these factors. To determine whether (1) fever in the first 48 hours is related to a favorable outcome in trauma patients and (2) fever is more common in patients with head trauma. Retrospective study of trauma patients admitted to the intensive care unit for at least 2 days. Data were analyzed by using multivariate analysis. Of 162 patients studied, 40% had fever during the first 48 hours. Febrile patients had higher mortality rates than did afebrile patients. When adjusted for severity of injuries, fever did not correlate with mortality. Neither the incidence of fever in the first 48 hours after admission to the intensive care unit nor the number of days febrile in the unit differed between patients with and patients without head trauma (traumatic brain injury). About 70% of febrile patients did not have a source found for their fever. Febrile patients without an identified source of infection had lower peak white blood cell counts, lower maximum body temperature, and higher minimum platelet counts than did febrile patients who had an infectious source identified. The most common infection was pneumonia. No relationship was found between the presence of fever during the first 48 hours and mortality. Patients with traumatic brain injury did not have a higher incidence of fever than did patients without traumatic brain injury. About 30% of febrile patients had an identifiable source of infection. Further studies are needed to understand the origin and role of fever in trauma patients. ©2015 American Association of Critical-Care Nurses.

  16. Health Promotion Behavior of Chinese International Students in Korea Including Acculturation Factors: A Structural Equation Model.

    Science.gov (United States)

    Kim, Sun Jung; Yoo, Il Young

    2016-03-01

    The purpose of this study was to explain the health promotion behavior of Chinese international students in Korea using a structural equation model including acculturation factors. A survey using self-administered questionnaires was employed. Data were collected from 272 Chinese students who have resided in Korea for longer than 6 months. The data were analyzed using structural equation modeling. The p value of final model is .31. The fitness parameters of the final model such as goodness of fit index, adjusted goodness of fit index, normed fit index, non-normed fit index, and comparative fit index were more than .95. Root mean square of residual and root mean square error of approximation also met the criteria. Self-esteem, perceived health status, acculturative stress and acculturation level had direct effects on health promotion behavior of the participants and the model explained 30.0% of variance. The Chinese students in Korea with higher self-esteem, perceived health status, acculturation level, and lower acculturative stress reported higher health promotion behavior. The findings can be applied to develop health promotion strategies for this population. Copyright © 2016. Published by Elsevier B.V.

  17. Factors associated with breast self-examination among Malaysian women teachers.

    Science.gov (United States)

    Parsa, P; Kandiah, M; Parsa, N

    2011-06-01

    The purpose of this study was to examine factors related to breast self-examination (BSE) among teachers in Selangor, Malaysia. A cross-sectional study was conducted among 425 female teachers in 20 randomly selected secondary schools. A self-administered questionnaire based on the health belief model was randomly selected secondary schools. A self-administered questionnaire based on the health belief model was used, including sociodemographic background and knowledge, beliefs and practices about breast cancer and BSE. Only 19% of the women performed BSE on a regular basis. Higher knowledge about breast cancer, greater confidence in performing BSE and regular visits to a physician were significant predictors for practising BSE. To promote BSE practice among Malaysian women, tailored health education and health promotion programmes should be developed based on a specific understanding of women's health beliefs.

  18. Examining factors involved in stress-related working memory impairments: Independent or conditional effects?

    Science.gov (United States)

    Banks, Jonathan B; Tartar, Jaime L; Tamayo, Brittney A

    2015-12-01

    A large and growing body of research demonstrates the impact of psychological stress on working memory. However, the typical study approach tests the effects of a single biological or psychological factor on changes in working memory. The current study attempted to move beyond the standard single-factor assessment by examining the impact of 2 possible factors in stress-related working memory impairments. To this end, 60 participants completed a working memory task before and after either a psychological stressor writing task or a control writing task and completed measures of both cortisol and mind wandering. We also included a measure of state anxiety to examine the direct and indirect effect on working memory. We found that mind wandering mediated the relationship between state anxiety and working memory at the baseline measurement. This indirect relationship was moderated by cortisol, such that the impact of mind wandering on working memory increased as cortisol levels increased. No overall working memory impairment was observed following the stress manipulation, but increases in state anxiety and mind wandering were observed. State anxiety and mind wandering independently mediated the relationship between change in working memory and threat perception. The indirect paths resulted in opposing effects on working memory. Combined, the findings from this study suggest that cortisol enhances the impact of mind wandering on working memory, that state anxiety may not always result in stress-related working memory impairments, and that high working memory performance can protect against mind wandering.

  19. Confirmatory Factor Analysis of WAIS-IV in a Clinical Sample: Examining a Bi-Factor Model

    Directory of Open Access Journals (Sweden)

    Rachel Collinson

    2016-12-01

    Full Text Available There have been a number of studies that have examined the factor structure of the Wechsler Adult Intelligence Scale IV (WAIS-IV using the standardization sample. In this study, we investigate its factor structure on a clinical neuropsychology sample of mixed aetiology. Correlated factor, higher-order and bi-factor models are all tested. Overall, the results suggest that the WAIS-IV will be suitable for use with this population.

  20. Confirmatory Factor Analysis of WAIS-IV in a Clinical Sample: Examining a Bi-Factor Model

    OpenAIRE

    Rachel Collinson; Stephen Evans; Miranda Wheeler; Don Brechin; Jenna Moffitt; Geoff Hill; Steven Muncer

    2016-01-01

    There have been a number of studies that have examined the factor structure of the Wechsler Adult Intelligence Scale IV (WAIS-IV) using the standardization sample. In this study, we investigate its factor structure on a clinical neuropsychology sample of mixed aetiology. Correlated factor, higher-order and bi-factor models are all tested. Overall, the results suggest that the WAIS-IV will be suitable for use with this population.

  1. 体育纳入高考制度的理性思考%Rational thinking about including physical education in the National College Entrance Examination system

    Institute of Scientific and Technical Information of China (English)

    周茗

    2012-01-01

      我国高考的目的是选拔德、智、体全面发展的社会主义建设者和接班人。将体育纳入高考的改革,有利于落实国家相关政策,保持基础教育阶段学生健康教育的连续性,加强素质教育,促进学校体育地位的提高和体育活动的开展,但也受到政治、经济、社会、技术等因素的制约。%  The purpose of National College Entrance Examination (NCEE) in China is to select morally, intellectu-ally and physically developed socialist constructors and successors. Including physical education in the reform of NCEE is conducive to implementing related state policies, maintaining the continuity of student health education at the basic education stage, enhancing makings education, and boosting the promotion of school physical education status and the development of physical education activities, but also affected and restricted by factors such as poli-tics, economy, society, technology etc.

  2. Examination of the Factor Structure and Concurrent Validity of the Langer Mindfulness/Mindlessness Scale

    Science.gov (United States)

    Haigh, Emily A. P.; Moore, Michael T.; Kashdan, Todd B.; Fresco, David M.

    2011-01-01

    Langer's theory of mindfulness proposes that a mindful person seeks out and produces novelty, is attentive to context, and is flexible in thought and behavior. In three independent studies, the factor structure of the Langer Mindfulness/Mindlessness Scale was examined. Confirmatory factor analysis failed to replicate the four-factor model and a…

  3. Factors associated with medical student test anxiety in objective structured clinical examinations: a preliminary study

    Science.gov (United States)

    2016-01-01

    Objectives To investigate attributes of medical students associated with their test anxiety on Objective Structured Clinical Examinations (OSCEs). Methods A cross-sectional study using a self-administered questionnaire was conducted of all Year 3 and 4 students at a private medical school in South Korea in 2014. This 53-item questionnaire consisted of factors pertaining to test anxiety on the OSCE identified from a review of relevant literature, which included students’ motivational beliefs and achievement emotions, perceived values of the OSCE, and attitude and orientation towards patients. Participants’ test anxiety levels were measured using the Korean Achievement Emotions Questionnaire. Participants rated their responses using a five-point Likert-type scale. Univariate analysis was performed to examine relationships between the variables. Results A total of 94 students completed the questionnaire (a 93% response rate). No differences in the participants’ test anxiety scores were observed across genders, entry-levels, or years in medical school. Participants’ test anxiety on the OSCE showed moderate association with their class-related achievement emotions (i.e., anxiety and boredom), where r = 0.46 and 0.32, p OSCE (r = -0.21, p OSCE. These findings have implications for developing effective educational interventions for helping students cope with such a stress by enhancing our understanding of the various factors that influence their test anxiety in OSCEs. PMID:28035056

  4. Factors associated with medical student test anxiety in objective structured clinical examinations: a preliminary study.

    Science.gov (United States)

    Kim, Kyong-Jee

    2016-12-29

    To investigate attributes of medical students associated with their test anxiety on Objective Structured Clinical Examinations (OSCEs). A cross-sectional study using a self-administered questionnaire was conducted of all Year 3 and 4 students at a private medical school in South Korea in 2014. This 53-item questionnaire consisted of factors pertaining to test anxiety on the OSCE identified from a review of relevant literature, which included students' motivational beliefs and achievement emotions, perceived values of the OSCE, and attitude and orientation towards patients. Participants' test anxiety levels were measured using the Korean Achievement Emotions Questionnaire. Participants rated their responses using a five-point Likert-type scale. Univariate analysis was performed to examine relationships between the variables. A total of 94 students completed the questionnaire (a 93% response rate). No differences in the participants' test anxiety scores were observed across genders, entry-levels, or years in medical school. Participants' test anxiety on the OSCE showed moderate association with their class-related achievement emotions (i.e., anxiety and boredom), where r = 0.46 and 0.32, p anxiety on the OSCE. These findings have implications for developing effective educational interventions for helping students cope with such a stress by enhancing our understanding of the various factors that influence their test anxiety in OSCEs.

  5. Factorization of Radiative Leptonic Decays of $B^-$ and $D^-$ Mesons Including the Soft Photon Region

    CERN Document Server

    Yang, Ji-Chong

    2016-01-01

    In this work, we study the radiative leptonic decays of $B^-$ and $D^-$ mesons using factorization approach. Factorization is proved to be valid explicitly at 1-loop level at any order of $O(\\Lambda _{\\rm QCD}\\left/m_Q\\right.)$. We consider the contribution in the soft photon region that $E_{\\gamma} \\sim \\left. \\Lambda^2 _{\\rm QCD} /\\right. m_Q$. The numerical results shows that, the soft photon region is very important for both the $B$ and $D$ mesons. The branching ratios of $B\\to \\gamma e\

  6. Situational effects of the school factors included in the dynamic model of educational effectiveness

    NARCIS (Netherlands)

    Creerners, Bert; Kyriakides, Leonidas

    2009-01-01

    We present results of a longitudinal study in which 50 schools, 113 classes and 2,542 Cypriot primary students participated. We tested the validity of the dynamic model of educational effectiveness and especially its assumption that the impact of school factors depends on the current situation of th

  7. Latina Resilience in Higher Education: Contributing Factors Including Seasonal Farmworker Experiences

    Science.gov (United States)

    Graff, Cristina Santamaria; McCain, Terrence; Gomez-Vilchis, Veronica

    2013-01-01

    Many Latina students overcome multiple obstacles to earn university degrees. Five married Latina women with children and seasonal farmworker backgrounds are the focus of this study which is analyzed through resiliency theory to understand factors contributing to their academic resilience. Variables connected to academic success are explored and…

  8. Alcoholism, associated risk factors, and harsh parenting among fathers: Examining the role of marital aggression.

    Science.gov (United States)

    Finger, Brent; Kachadourian, Lorig K; Molnar, Danielle S; Eiden, Rina D; Edwards, Ellen P; Leonard, Kenneth E

    2010-06-01

    This study utilized a longitudinal design to examine relations between paternal alcoholism, paternal psychopathology, marital aggression and fathers' harsh parenting behavior in a sample of children with alcoholic (n = 89) and non-alcoholic (n = 94) fathers. Structural Equation Modeling revealed that paternal alcoholism, depression, and antisocial behavior at 12 months of child age each predicted higher levels of marital aggression at 36 months. Moreover, after controlling for prior parenting, marital aggression was predictive of harsher parenting at kindergarten. Alcoholism and psychopathology were not directly predictive of harsh parenting with marital aggression included in the model, thus indicating that marital aggression is mediating the relation between paternal risk factors and parenting outcome. Results of this study suggest that one pathway linking fathers' alcohol diagnosis to harsh parenting is via marital aggression.

  9. Simultaneous Spectrophotometric Determination of Four Components including Acetaminophen by Taget Factor Analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    UV Spectrophotometric Target Factor Analysis (TFA) was used for the simultaneous determination of four components (acetaminophen, guuaifenesin, caffeine, Chlorphenamine maleate) in cough syrup. The computer program of TFA is based on VC++ language. The difficulty of overlapping of absorption spectra of four compounds was overcome by this procedure. The experimental results show that the average recovery of each component is all in the range from 98.9% to 106.8% and each component obtains satisfactory results without any pre-separation.

  10. The N(H2/I(CO Conversion Factor: A Treatment that Includes Radiative Transfer

    Directory of Open Access Journals (Sweden)

    W. F. Wall

    2006-01-01

    Full Text Available Se presenta un tratamiento que explica mejor el factor de conversión N(H2=I(CO y que incluye la transferencia radiativa. A primera vista, incluir la transferencia radiativa parece superfluo para una línea óptimamente gruesa como CO J = 1 0. No obstante, dado que el medio interestelar es inhomogéneo, los fragmentos de gas (es decir, grumos todavía pueden ser óptimamente delgadas hacia sus bordes y en las alas de los pérfiles de la línea. El tratamiento estadístico de Martin et al. (1984 de la transferencia radiativa a través una nube molecular con grumos se usa para derivar una expresión para el factor de conversión que su- pera los defectos de las explicaciones más tradicionales basadas en Dickman et al. (1986. Por un lado, el tratamiento presentado aquí posiblemente representa un avance importante al entender el factor de conversión N(H2=I(CO pero, por otro lado, tiene sus propios defectos, que son discutidos aquí brevemente.

  11. Preoperative Serum Interleukin-6 Is a Potential Prognostic Factor for Colorectal Cancer, including Stage II Patients

    Directory of Open Access Journals (Sweden)

    Kazuyoshi Shiga

    2016-01-01

    Full Text Available Aims. To evaluate the prognostic significance of serum interleukin-6 (IL-6 in colorectal cancer (CRC. Patients and Methods. Preoperative serum IL-6 was measured in 233 CRC patients and 13 healthy controls. Relationships between IL-6 and various clinicopathological factors were evaluated, and the overall survival (OS and disease-free survival (DFS rates according to IL-6 status were calculated for all patients and according to disease stage. Results. The mean IL-6 level was 6.6 pg/mL in CRC patients and 2.6 pg/mL in healthy controls. Using a cutoff of 6.3 pg/mL, obtained using receiver operating characteristic curve analysis, 57 patients had a high IL-6 level. The mean value was higher for stage II disease than for stage III disease. IL-6 status correlated with C-reactive protein (CRP and carcinoembryonic antigen levels, obstruction, and pT4 disease. The OS differed according to the IL-6 status for all patients, whereas the DFS differed for all patients and for those with stage II disease. The Cox proportional hazards model showed that pT4 disease was an independent risk factor for recurrence in all CRC patients; IL-6, CRP, and pT4 were significant risk factors in stage II patients. Conclusions. The preoperative IL-6 level influences the risk of CRC recurrence.

  12. Current Changes in Pubertal Timing: Revised Vision in Relation with Environmental Factors Including Endocrine Disruptors.

    Science.gov (United States)

    Parent, Anne-Simone; Franssen, Delphine; Fudvoye, Julie; Pinson, Anneline; Bourguignon, Jean-Pierre

    2016-01-01

    The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on environmental factor effects and underlying mechanisms. A current advancement in timing of female puberty is usually emphasized. It appears, however, that timing is also changing in males. Moreover, the changes are towards earliness for initial pubertal stages and towards lateness for final stages in both sexes. Such observations indicate the complexity of environmental influences on pubertal timing. The mechanisms of changes in pubertal timing may involve both the central neuroendocrine control and peripheral effects at tissues targeted by gonadal steroids. While sufficient energy availability is a clue to the mechanism of pubertal development, changes in the control of both energy balance and reproduction may vary under the influence of common determinants such as endocrine-disrupting chemicals (EDCs). These effects can take place right before puberty as well as much earlier, during fetal and neonatal life. Finally, environmental factors can interact with genetic factors in determining changes in pubertal timing. Therefore, the variance in pubertal timing is no longer to be considered under absolutely separate control by environmental and genetic determinants. Some recommendations are provided for evaluation of EDC impact in the management of pubertal disorders and for possible reduction of EDC exposure along the precautionary principle.

  13. Examining the Factors That Influence Students' Science Learning Processes and Their Learning Outcomes: 30 Years of Conceptual Change Research

    Science.gov (United States)

    Lin, Jing-Wen; Yen, Miao-Hsuan; Liang, Jia-Chi; Chiu, Mei-Hung; Guo, Chorng-Jee

    2016-01-01

    This study used content analysis to examine the most studied conceptual change factors that influence students' science learning processes and their learning outcomes. The reviewed research included empirical studies published since Posner et al. proposed their conceptual change model 30 years ago (from 1982 to 2011). One hundred sixteen SSCI…

  14. Revisiting the Leadership Scale for Sport: Examining Factor Structure Through Exploratory Structural Equation Modeling.

    Science.gov (United States)

    Chiu, Weisheng; Rodriguez, Fernando M; Won, Doyeon

    2016-10-01

    This study examines the factor structure of the shortened version of the Leadership Scale for Sport, through a survey of 201 collegiate swimmers at National Collegiate Athletic Association Division II and III institutions, using both exploratory structural equation modeling and confirmatory factor analysis. Both exploratory structural equation modeling and confirmatory factor analysis showed that a five-factor solution fit the data adequately. The sizes of factor loadings on target factors substantially differed between the confirmatory factor analysis and exploratory structural equation modeling solutions. In addition, the inter-correlations between factors of the Leadership Scale for Sport and the correlations with athletes' satisfaction were found to be inflated in the confirmatory factor analysis solution. Overall, the findings provide evidence of the factorial validity of the shortened Leadership Scale for Sport.

  15. Examining influential factors in providers’ chronic pain treatment decisions: a comparison of physicians and medical students

    OpenAIRE

    2015-01-01

    Background Chronic pain treatment guidelines are unclear and conflicting, which contributes to inconsistent pain care. In order to improve pain care, it is important to understand the various factors that providers rely on to make treatment decisions. The purpose of this study was to examine factors that reportedly influence providers’ chronic pain treatment decisions. A secondary aim was to examine differences across participant training level. Methods Eighty-five participants (35 medical st...

  16. Nuclear monopole charge form factor calculation for relativistic models including center-of-mass corrections

    Energy Technology Data Exchange (ETDEWEB)

    Avancini, S.S.; Marinelli, J.R. [Universidade Federal de Santa Catarina Florianopolis, Depto de Fisica - CFM, Florianopolis (Brazil); Carlson, B.V. [Instituto Tecnologico de Aeronautica, Sao Jose dos Campos (Brazil)

    2013-06-15

    Relativistic models for finite nuclei contain spurious center-of-mass motion in most applications for the nuclear many-body problem, where the nuclear wave function is taken as a single Slater determinant within a space-fixed frame description. We use the Peierls-Yoccoz projection method, previously developed for relativistic approaches together with a reparametrization of the coupling constants that fits binding energies and charge radius and apply our results to calculate elastic electron scattering monopole charge form factors for light nuclei. (orig.)

  17. SUBSTANTIATION OF THE COST OF HOUSING CONSTRUCTION INCLUDING THE FACTOR OF INVESTMENT ATTRACTIVENESS OF TERRITORIES

    Directory of Open Access Journals (Sweden)

    ZAIATS Yi. I.

    2015-11-01

    Full Text Available Problem statement. For planning and organization of urban construction is necessary to analyze the use of areas. Territorial resources of the city, being used for construction and other urban purposes, consists of plots of land: disposable, reserved and undeveloped in previous years of construction in progress; residential districts and blocks of obsolete housing fund; industrial and municipal and warehouse enterprises being used irrationally or stopped to work; the defence department, where the amortized warehouses and other main funds are that are not used by purpose; agricultural enterprises where the obsolete industrial funds, haying, nurseries, greenhouses. The number of free areas suitable for future urban development is extremely limited. However a considerable part of the territories of almost all functional zones is used inefficiently. Purpose. Formalization of a factor of investment attractiveness of territories for the further identification and research of the connection between it and the cost of housing construction is necessary. Conclusion. The identification of regularities of influence of the factor of investment attractiveness of territories on the cost of construction of high-rise buildings allow to obtain a quantitative estimate of this effect and can be used in the development of the methodology of substantiation of the expediency and effectiveness of the implementation of highrise construction projects, based on organizational and technological aspects.

  18. Psychometric Structure of a Comprehensive Objective Structured Clinical Examination: A Factor Analytic Approach

    Science.gov (United States)

    Volkan, Kevin; Simon, Steven R.; Baker, Harley; Todres, I. David

    2004-01-01

    Problem Statement and Background: While the psychometric properties of Objective Structured Clinical Examinations (OSCEs) have been studied, their latent structures have not been well characterized. This study examines a factor analytic model of a comprehensive OSCE and addresses implications for measurement of clinical performance. Methods: An…

  19. Examining Success Factors Related to ERP Implementations in Higher Education Shared Services Projects

    Science.gov (United States)

    Stoyanoff, Dawn Galadriel Pfeiffer

    2012-01-01

    This study examined the enterprise resource planning (ERP) implementations that utilized a shared services model in higher education. The purpose of this research was to examine the critical success factors which were perceived to contribute to project success. This research employed a quantitative non-experimental correlational design and the…

  20. Form or Flesh: Social Factors That Impact Women's Practice of Breast Self-Examination.

    Science.gov (United States)

    London, Patricia A.

    The social factors that impact Caucasian middle-class women's practice of breast self-examination (BSE) were examined through in-depth interviews with 15 women who were selected to represent a mix of women who practiced BSE monthly, occasionally, or never. The meaning of BSE was analyzed in relation to body image and the social definition of being…

  1. School Violence in Taiwan: Examining How Western Risk Factors Predict School Violence in an Asian Culture

    Science.gov (United States)

    Chen, Ji-Kang; Astor, Ron Avi

    2010-01-01

    The current study explores whether theorized risk factors in Western countries can be used to predict school violence perpetration in an Asian cultural context. The study examines the associations between risk factors and school violence perpetration in Taiwan. Data were obtained from a nationally representative sample of 14,022 students from…

  2. Modelling of safety barriers including human and organisational factors to improve process safety

    DEFF Research Database (Denmark)

    Markert, Frank; Duijm, Nijs Jan; Thommesen, Jacob

    2013-01-01

    explosion, and the Mont Blanc Tunnel Fire, such an approach may have helped to maintain the integrity of the designed provisions against major deviations resulting in these disasters. In order to make this paradigm operational, safety management and in particular risk assessment tools need to be refined....... A valuable approach is the inclusion of human and organisational factors into the simulation of the reliability of the technical system using event trees and fault trees and the concept of safety barriers. This has been demonstrated e.g. in the former European research project ARAMIS (Accidental Risk...... Assessment Methodology for IndustrieS, see Salvi et al 2006). ARAMIS employs the bow-tie approach to modelling hazardous scenarios, and it suggests the outcome of auditing safety management to be connected to a semi-quantitative assessment of the quality of safety barriers. ARAMIS discriminates a number...

  3. Contribution of Environmental Risk Factors Including Lifestyle to Inequalities Noncommunicable (Chronic Diseases such as Diabetes

    Directory of Open Access Journals (Sweden)

    Elzbieta Grochowska Niedworok

    2015-06-01

    Full Text Available Health inequalities: differences in health status or in the distribution of health determinants between different population groups. Some health inequalities are attributable to biological variations or free choice and others are attributable to the external environment and conditions mainly outside the control of the individuals concerned. 347 million people worldwide have diabetes. In 2012 an estimated 1.5 million deaths were directly caused by diabetes. More than 80% of diabetes deaths occur in low- and middle-income countries. WHO projects that diabetes will be the 7th leading cause of death in 2030. Healthy diet, regular physical activity and maintaining a normal body weight can prevent or delay the onset of type 2 diabetes. Risk factors: 1. Age- the prevalence of diabetes rises steeply with age: *one in twenty people over the age of 65 have diabetes, *and this rises to one in five people over the age of 85 years. The diagnosis of diabetes may be delayed in older people, with symptoms of diabetes being wrongly attributed to ageing. 2. Ethnic: type 2 diabetes is up to six times more common in people of South Asian descent and up to three times more common in those of African and African-Caribbean descent then in the white population. It is also more common in people of Chinese descent and other non-Caucasian groups. 3. Gender: the frequency of diabetes usually is higher in men than in women. This may be because gender compounds other aspects of inequality- women often bear the brunt of poverty, and socio-economic differences in the prevalence of diabetes are more marked for women, probably because of differences in smoking rates, food choices and the prevalence of obesity. 4. Overweight/Obesity: every 1 kg/m2 more causes increase risk: cardiovascular diseases 2%, coronary artery disease- 3% , myocardial infarction- 5% , heart failure- 5% , peripheral vascular disease- 5%. Health inqualities important in diabetes -- modifiable:  social

  4. Clinical characteristics of Pneumocystis pneumonia in non-HIV patients and prognostic factors including microbiological genotypes

    Directory of Open Access Journals (Sweden)

    Ito Yutaka

    2011-03-01

    Full Text Available Abstract Background The number of patients with non-HIV Pneumocystis pneumonia (PCP is increasing with widespread immunosuppressive treatment. We investigated the clinical characteristics of non-HIV PCP and its association with microbiological genotypes. Methods Between January 2005 and March 2010, all patients in 2 university hospitals who had been diagnosed with PCP by PCR were enrolled in this study. Retrospective chart review of patients, microbiological genotypes, and association with 30-day mortality were examined. Results Of the 82 adult patients investigated, 50 patients (61% had inflammatory diseases, 17 (21% had solid malignancies, 12 (15% had hematological malignancies, and 6 (7% had received transplantations. All patients received immunosuppressive agents or antitumor chemotherapeutic drugs. Plasma (1→3 β-D-glucan levels were elevated in 80% of patients, and were significantly reduced after treatment in both survivors and non-survivors. However, β-D-glucan increased in 18% of survivors and was normal in only 33% after treatment. Concomitant invasive pulmonary aspergillosis was detected in 5 patients. Fifty-six respiratory samples were stored for genotyping. A dihydropteroate synthase mutation associated with trimethoprim-sulfamethoxazole resistance was found in only 1 of the 53 patients. The most prevalent genotype of mitochondrial large-subunit rRNA was genotype 1, followed by genotype 4. The most prevalent genotype of internal transcribed spacers of the nuclear rRNA operon was Eb, followed by Eg and Bi. Thirty-day mortality was 24%, in which logistic regression analysis revealed association with serum albumin and mechanical ventilation, but no association with genotypes. Conclusions In non-HIV PCP, poorer general and respiratory conditions at diagnosis were independent predictors of mortality. β-D-glucan may not be useful for monitoring the response to treatment, and genotypes were not associated with mortality.

  5. Examination of patient factors and contrast medium factors that exert influence on contrast enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, Isao; Morimoto, Akira; Shouga, Kazuhiko; Suzuki, Noriyuki [Kure Kyosai Hospital, Hiroshima (Japan)

    2002-04-01

    The purpose of this study was to determine the relationship between patient factors and contrast medium factors, both of which influence contrast enhancement. Our goal was to achieve improved standardization and reproducibility of enhancement based on the findings of this study. Enhancement units (EU) and the contrast enhancement index (CE index) were calculated in the areas of the hepatic parenchyma and abdominal aorta in 370 subjects who underwent our hepatic dynamic study. We analyzed the obtained values in terms of differences in age, sex, body weight, iodine volume per body weight, and volume and concentration of contrast medium. Changes in EU values were dependent on total iodine volume and body weight, showing a positive correlation with iodine volume per body weight. When assessed in terms of fixed total volume, the values were found to show a negative correlation with body weight. The obtained CE index values were closely distributed on a fixed iodine volume per weight, with slight variations that were related to sex, body weight, and age. Particularly, in the analysis of changes in enhancement levels according to age, a notable increase in contrast enhancement in inverse relationship with decline in glomerular filtration rate (GFR) with aging was observed. (author)

  6. Awareness of breast cancer risk factors and practice of breast self examination among high school students in Turkey.

    Science.gov (United States)

    Karayurt, Ozgül; Ozmen, Dilek; Cetinkaya, Aynur Cakmakçi

    2008-10-17

    Young breast cancer patients have a lower rate of survival than old breast cancer patients due to being diagnosed at advanced stages. Breast self-examination makes women more "breast aware", which in turn may lead to an earlier diagnosis of breast cancer. The purpose of this study was to investigate knowledge and practice of breast self-examination and to determine knowledge of risk factors for breast cancer among high school students. This is a descriptive and cross-sectional study. It was conducted in a high school in Manisa, Turkey. The study sample included 718 female high school students. A socio-demographic characteristics data form, knowledge of breast self examination and risk factors for breast cancer form and breast self examination practice form were used to collect data. The female high school students had insufficient knowledge about breast self-examination and a low percentage of students reported that they had performed breast self examination monthly. The most common reason for not doing breast self- examination was "not knowing how to perform breast self-examination" (98.5%). Most of the students had little knowledge of the risk factors for breast cancer. The most widely known risk factor by the students was personal history of breast cancer (68.7%). There was a significant relation between breast self-examination practice and age, school grade, knowledge about breast cancer and knowledge about breast self- examination. There is a need to increase knowledge of adolescent females about the risks of breast cancer and benefits of early detection. In fact, health care professionals can develop effective breast health care programs and help young women to acquire good health habits.

  7. Awareness of breast cancer risk factors and practice of breast self examination among high school students in Turkey

    Directory of Open Access Journals (Sweden)

    Çetinkaya Aynur

    2008-10-01

    Full Text Available Abstract Background Young breast cancer patients have a lower rate of survival than old breast cancer patients due to being diagnosed at advanced stages. Breast self-examination makes women more "breast aware", which in turn may lead to an earlier diagnosis of breast cancer. The purpose of this study was to investigate knowledge and practice of breast self-examination and to determine knowledge of risk factors for breast cancer among high school students. Methods This is a descriptive and cross-sectional study. It was conducted in a high school in Manisa, Turkey. The study sample included 718 female high school students. A socio-demographic characteristics data form, knowledge of breast self examination and risk factors for breast cancer form and breast self examination practice form were used to collect data. Results The female high school students had insufficient knowledge about breast self-examination and a low percentage of students reported that they had performed breast self examination monthly. The most common reason for not doing breast self- examination was "not knowing how to perform breast self-examination" (98.5%. Most of the students had little knowledge of the risk factors for breast cancer. The most widely known risk factor by the students was personal history of breast cancer (68.7%. There was a significant relation between breast self-examination practice and age, school grade, knowledge about breast cancer and knowledge about breast self- examination. Conclusion There is a need to increase knowledge of adolescent females about the risks of breast cancer and benefits of early detection. In fact, health care professionals can develop effective breast health care programs and help young women to acquire good health habits.

  8. A patient with refractory shock induced by several factors, including obstruction because of a posterior mediastinal hematoma.

    Science.gov (United States)

    Obinata, Mariko; Ishikawa, Kouhei; Osaka, Hiromichi; Mishima, Kentaro; Omori, Kazuhiko; Oode, Yasumasa; Yanagawa, Youichi

    2015-06-01

    A 44-year-old man who drove a motorcycle experienced a collision with the side of another motorcycle. Because he had sustained a high-energy injury to the spinal cord, he was transferred to our hospital. His circulation was unstable, and received tracheal intubation in addition to thoracostomy for the hemothorax. Whole-body computed tomography (CT) revealed multiple fractures, right hemopneumothorax with pulmonary contusion, and minor liver injury. After infusing 5000 mL of lactated Ringer's solution and 10 units of blood, his circulation remained unstable. On a repeat CT examination, the left atrium was found to be compressed by a posterior mediastinal hematoma induced by the fracture of the thoracic spine, and a diagnosis of shock induced by multiple factors, including hemorrhagic, neurogenic, and obstructive mechanisms, was made. After obtaining stable circulation and respirations, internal fixation of the extremities and extubation were performed on the 12th hospital day. Chest CT performed on the 27th day showed the disappearance of compression of the left atrium by the hematoma.

  9. Examining Word Factors and Child Factors for Acquisition of Conditional Sound-Spelling Consistencies: A Longitudinal Study

    Science.gov (United States)

    Kim, Young-Suk Grace; Petscher, Yaacov; Park, Younghee

    2016-01-01

    It has been suggested that children acquire spelling by picking up conditional sound-spelling consistencies. To examine this hypothesis, we investigated how variation in word characteristics (words that vary systematically in terms of phoneme-grapheme correspondences) and child factors (individual differences in the ability to extract…

  10. Examining Word Factors and Child Factors for Acquisition of Conditional Sound-Spelling Consistencies: A Longitudinal Study

    Science.gov (United States)

    Kim, Young-Suk Grace; Petscher, Yaacov; Park, Younghee

    2016-01-01

    It has been suggested that children acquire spelling by picking up conditional sound-spelling consistencies. To examine this hypothesis, we investigated how variation in word characteristics (words that vary systematically in terms of phoneme-grapheme correspondences) and child factors (individual differences in the ability to extract…

  11. Factors Contributing to Examination Malpractices at Secondary School Level in Kohat Division, Pakistan

    Directory of Open Access Journals (Sweden)

    Qaiser Suleman

    2015-05-01

    Full Text Available The purpose of this research work was to identify the factors that contribute to examination malpractices at secondary school level. The target population of the study was all the heads, teachers and students at secondary school level in Kohat Division (Pakistan. The study was delimited to the 80 male secondary schools. The sample for this study was made up of 840 respondents which were selected through simple random sampling technique. A self-developed semi-structured questionnaire was used as research instrument for data collection. Descriptive statistics i.e., simple percentage, mean, standard deviation and inferential statistics i.e., ANOVA were applied for the statistical analysis of data. The findings of the study explored that there are various factors that contribute to examination malpractices i.e., corruption; poor implementation of examinations rules; students and parental threats; no fear of punishment; inadequate preparation for examination; poor invigilation; collusion; disloyalty of examination bodies; fear of failure; poor morale and economic depression of supervisory staff etc. Furthermore, the findings of the study revealed that bringing of unauthorized materials to examination hall; sending of prepared answers to students by teachers and parents; impersonation; questions and papers leakage; cheating; and scripts changing are the various forms of examination malpractices. Based on findings, it was recommended that examination rules should be implemented effectively and those who were found guilty should be given severe exemplary punishment according to the examination’s rules.

  12. Factors influencing the decision to participate in medical premarital examinations in Hubei Province, Mid-China

    OpenAIRE

    Wang, Peigang; Wang, Xiao; Fang, Min; VanderWeele, Tyler J.

    2013-01-01

    Background: To investigate the attitudes of premarital couples towards the premarital screening program after the abolition of compulsory screening in China and to study the factors influencing participation. Methods: Between July 1st 2010 to August 31st 2010, 650 people who registered for marriage at the civil affairs bureau of Wuhan, Suizhou, Zaoyang in Hubei province were studied using questionnaires. Logistic regression was used to examine the factors influencing participation in the prem...

  13. Factors influencing the decision to participate in medical premarital examinations in Hubei Province, Mid-China

    OpenAIRE

    Wang, Peigang; Wang, Xiao; Fang, Min; Vander Weele, Tyler J

    2013-01-01

    Background To investigate the attitudes of premarital couples towards the premarital screening program after the abolition of compulsory screening in China and to study the factors influencing participation. Methods Between July 1st 2010 to August 31st 2010, 650 people who registered for marriage at the civil affairs bureau of Wuhan, Suizhou, Zaoyang in Hubei province were studied using questionnaires. Logistic regression was used to examine the factors influencing participation in the premar...

  14. An examination of the factors affecting the teaching and learning of evolution

    Science.gov (United States)

    Maldonado-Rivera, Jose Gabriel

    1998-12-01

    The factors affecting the teaching and learning of evolution were examined in the public schools of Puerto Rico. The study explored (1) the extent and nature of evolution education; (2) the role of teacher's attitudes, knowledge and beliefs in the teaching of evolution; (3) the nature and sources of student misconceptions; and (4) the extent to which conceptual change teaching can induce changes in these misconceptions. Questionnaires, interviews, and an experimental intervention were used to ascertain the factors affecting the teaching and learning of evolution. Among the study's major findings: (1) While evolution is present in the official curriculum, it is not treated as a central unifying theme. (2) In actual teaching evolution is completely neglected. (3) This neglect is due to several factors including: the religious beliefs of teachers; deficient pre-service training in particular poor training in history and philosophy of science, and deficient content and methods knowledge. (4) Students possess a wide variety of misconceptions about evolutionary theory. While some of these are ascribable to religion, many are related to other aspects of student affect, knowledge and cognition, including: (a) a misunderstanding of the nature of science; (b) methodological, epistemological and ontological commitments which difficultate comprehension; (c) the distorting influence of an anthropocentric, urban experience; (d) deficiencies in prior knowledge; and (e) an ahistoric worldview. (5) Conceptual change teaching was found to be more effective in transforming student views towards more scientific ones, than traditional didactic instruction. Conceptual change instruction: (a) increased the explanatory repertoire of students; (b) promoted greater changes towards more scientific conceptions; (c) increased student acceptance and understanding of evolutionary theory, and (d) induced more students to incorporate evolution in their explanations of biological phenomena. These

  15. An Examination of Rebuild America Partnership Accomplishments and the Factors Influencing Them

    Energy Technology Data Exchange (ETDEWEB)

    Schweitzer, M.

    2003-10-16

    The Rebuild America program was established in 1994 to accelerate the adoption of energy efficiency measures and practices in existing public facilities, commercial buildings, and multifamily housing units. More recently, the program has expanded to include new construction as well. The program encourages the formation of partnerships involving state and local governments, private businesses, and other organizations to help identify and solve problems related to energy use in buildings. Rebuild America does not directly fund actual building improvements. Instead, it provides the Rebuild Partners with the technical tools and assistance they need to plan and implement building projects and stimulates other entities to make substantial investments in energy efficiency. At the request of the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy, staff at Oak Ridge National Laboratory studied the Rebuild America program for the purpose of identifying key factors associated with successful operations. Substantial amounts of data were collected directly from Rebuild America partnerships concerning the results achieved by each of their individual projects, both committed and completed. In addition, data were collected from secondary sources on a limited number of factors describing partnership setting and characteristics. By combining these two data sets, we were able to perform statistical analyses testing the potential relationship between each partnership characteristic and each of four key results measures. The influences on successful partnership performance also were determined in another way, which allowed a broader examination of potentially important factors. Telephone interviews were conducted with representatives from 61 high-performing Rebuild America partnerships throughout the United States. The respondents were asked to identify the most important factors influencing good performance and the types of Rebuild America products

  16. Analysis on Factors Influencing Sustainable Development of Self-study Examination of Agricultural Science Disciplines

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Based on existing problems in the course of development of self-study examination of agricultural science disciplines, this paper analyzes logical conditions for its sustainable development. Major logical conditions include requirement for free and comprehensive development of individuals; requirement for social institutional evolution and change; requirement for fairness and justice of education and development; as well as requirement for better-established organization system and higher social reputation. Finally, it presents basic measures for sustainable development of self-study examination of agricultural science disciplines, including carrying on reasonable core elements of self-study examination system, adjusting structure of discipline, improving social assistance system, and expanding service space.

  17. Construct Validity of the Korean Dental Licensing Examination using Confirmatory Factor Analysis

    Directory of Open Access Journals (Sweden)

    Mi Kyoung Yim

    2005-06-01

    Full Text Available Confirmatory factor analysis based on a measurement model of a structural equation model was used to test the construct validity of 13 subjects in the Korean Dental Licensing Examination (KDLE. The results of 1,086 examinees who wrote the KDLE in 2004 were analyzed. The thirteen subjects were classified into 62 major categories and 122 intermediate categories. There were 364 items. A hierarchical model was constructed, including major and intermediate categories. The impact of the variables was determined by the standardized regression coefficient that related latent and measured variables in the measurement model. The KDLE showed a high goodness-of-fit with a root mean square error of approximation of 0.030 and a non-normed fit index of 0.998. When the latent variables for the major and intermediate categories were analyzed, the standardized regression coefficients of all of the subjects, with the exception of Health and Medical Legislation, were significant. From the result, we concluded that the 13 subjects showed constructive validity. In addition, the study model and data were very compatible. The subject Health and Medical Legislation had a low explanatory impact with respect to testing the ability of dentists to perform their jobs. This study suggests that similar psychometric studies are needed before integrating or deleting subjects on the KDLE, and to improve item development.

  18. Alcohol consumption among Chilean adolescents: Examining individual, peer, parenting and environmental factors

    Science.gov (United States)

    Sanhueza, Guillermo E.; Delva, Jorge; Bares, Cristina B.; Grogan-Kaylor, Andrew

    2012-01-01

    Aims This study examined whether adolescents from Santiago, Chile who had never drunk alcohol differed from those who had drunk alcohol but who had never experienced an alcohol-related problem, as well as from those who had drunk and who had experienced at least one alcohol-related problem on a number of variables from four domains - individual, peers, parenting, and environmental. Design Cross-sectional. Setting Community based sample. Participants 909 adolescents from Santiago, Chile. Measurements Data were analyzed with multinomial logistic regression to compare adolescents who had never drunk alcohol (non-drinkers) with i) those that had drunk but who had experienced no alcohol-related problems (non-problematic drinkers) and ii) those who had drunk alcohol and had experienced at least one alcohol-related problem (problematic drinkers). The analyses included individual, peer, parenting, and environmental factors while controlling for age, sex, and socioeconomic status. Findings Compared to non-drinkers, both non-problematic and problematic drinkers were older, reported having more friends who drank alcohol, greater exposure to alcohol ads, lower levels of parental monitoring, and more risk-taking behaviors. In addition, problematic drinkers placed less importance on religious faith to make daily life decisions and had higher perceptions of neighborhood crime than non-drinkers. Conclusions Prevention programs aimed at decreasing problematic drinking could benefit from drawing upon adolescents’ spiritual sources of strength, reinforcing parental tools to monitor their adolescents, and improving environmental and neighborhood conditions. PMID:24465290

  19. Age-Related Differences in Emotion Regulation Strategies: Examining the Role of Contextual Factors

    Science.gov (United States)

    Schirda, Brittney; Valentine, Thomas R.; Aldao, Amelia; Prakash, Ruchika Shaurya

    2016-01-01

    Increasing age is characterized by greater positive affective states. However, there is mixed evidence on the implementation of emotion regulation strategies across the life span. To clarify the discrepancies in the literature, we examined the modulating influence of contextual factors in understanding emotion regulation strategy use in older and…

  20. Jordanian Mothers' Perceptions of Their Children's Social Competence: An Examination of Family Factors and Demographic Variables

    Science.gov (United States)

    Abu Taleb, Tagreed Fathi; AlZoubi, Rifa Rafe

    2015-01-01

    Children's social competence is an area of research that receives minimal attention from Jordanian researchers. It is important to investigate this area of development so as to provide parents with information about the nature of social competence and possible factors affecting its development. This research study examined Jordanian mothers'…

  1. Jordanian Mothers' Perceptions of Their Children's Social Competence: An Examination of Family Factors and Demographic Variables

    Science.gov (United States)

    Abu Taleb, Tagreed Fathi; AlZoubi, Rifa Rafe

    2015-01-01

    Children's social competence is an area of research that receives minimal attention from Jordanian researchers. It is important to investigate this area of development so as to provide parents with information about the nature of social competence and possible factors affecting its development. This research study examined Jordanian mothers'…

  2. An Exploratory Factor Analysis Examining Traits, Perceived Fit and Job Satisfaction in Employed College Graduates

    Science.gov (United States)

    Brandon, John R.

    2011-01-01

    This study is an analysis of 24 variables associated with employee attitudes, behaviors and outcomes. A total of 140 college graduates participated in the study. Utilizing exploratory factor analysis (EFA) techniques, the research examined relationships among the following variables: perceived fit, job satisfaction, cognitive ability, vocational…

  3. An Examination of Factors Influencing Students Selection of Business Majors Using TRA Framework

    Science.gov (United States)

    Kumar, Anil; Kumar, Poonam

    2013-01-01

    Making decisions regarding the selection of a business major is both very important and challenging for students. An understanding of this decision-making process can be valuable for students, parents, and university programs. The current study applies the Theory of Reasoned Action (TRA) consumer decision-making model to examine factors that…

  4. Examining Factors Affecting Science Achievement of Hong Kong in PISA 2006 Using Hierarchical Linear Modeling

    Science.gov (United States)

    Lam, Terence Yuk Ping; Lau, Kwok Chi

    2014-01-01

    This study uses hierarchical linear modeling to examine the influence of a range of factors on the science performances of Hong Kong students in PISA 2006. Hong Kong has been consistently ranked highly in international science assessments, such as Programme for International Student Assessment and Trends in International Mathematics and Science…

  5. Is Age The Major Factor in Second Language Acquisition? -- An examination of the Critical Period Hypothesis

    Institute of Scientific and Technical Information of China (English)

    LiYing; LiuShufan

    2004-01-01

    Children, unlike adults, have an innate ability for learning language with great facility and minimal effort. This idea that early age is a major factor in native-proficient second language acquisition is a widely held and popular belief. Such views have been supported by many theories that were first proposed in the middle of the 20th century. This paper examines the

  6. An Examination of Factors Influencing Students Selection of Business Majors Using TRA Framework

    Science.gov (United States)

    Kumar, Anil; Kumar, Poonam

    2013-01-01

    Making decisions regarding the selection of a business major is both very important and challenging for students. An understanding of this decision-making process can be valuable for students, parents, and university programs. The current study applies the Theory of Reasoned Action (TRA) consumer decision-making model to examine factors that…

  7. Community Violence Exposure and Adolescent Delinquency: Examining a Spectrum of Promotive Factors

    Science.gov (United States)

    Chen, Pan; Voisin, Dexter R.; Jacobson, Kristen C.

    2016-01-01

    This study examined whether promotive factors (future expectations, family warmth, school attachment, and neighborhood cohesion) moderated relationships between community violence exposure and youth delinquency. Analyses were conducted using N = 2,980 sixth to eighth graders (M[subscript age] = 12.48; 41.1% males) from a racially, ethnically, and…

  8. Examining the Factors Influencing Participants' Knowledge Sharing Behavior in Virtual Learning Communities

    Science.gov (United States)

    Chen, Irene Y. L.; Chen, Nian-Shing; Kinshuk

    2009-01-01

    Increasing organizations and educational institutions have implemented virtual learning communities to encourage knowledge sharing. However, this task can not be accomplished simply by grouping people together and telling them "sharing your knowledge will make you learn better". This research attempts to examine the factors influencing knowledge…

  9. Impact of Outliers Arising from Unintended and Unknowingly Included Subpopulations on the Decisions about the Number of Factors in Exploratory Factor Analysis

    Science.gov (United States)

    Liu, Yan; Zumbo, Bruno D.

    2012-01-01

    There is a lack of research on the effects of outliers on the decisions about the number of factors to retain in an exploratory factor analysis, especially for outliers arising from unintended and unknowingly included subpopulations. The purpose of the present research was to investigate how outliers from an unintended and unknowingly included…

  10. A Confirmatory Approach to Examining the Factor Structure of the Strengths and Difficulties Questionnaire (SDQ)

    DEFF Research Database (Denmark)

    Niclasen, Janni; Skovgaard, Anne Mette; Andersen, Anne-Marie Nybo

    2013-01-01

    four large scale cohorts. Three theoretical models were examined: 1. a model with five first order factors (i.e., hyperactivity/inattention, conduct, emotional, peer problems and prosocial), 2. a model adding two internalising and externalising second order factors to model 1, and 3. a model adding...... fits. Best model fits were found when two positively worded items were allowed to cross load with the prosocial scale, and cross loadings were allowed for among three sets of indicators. The analyses also revealed that model fits were slightly better for teachers than for parents and better for older...... a total difficulties second order factor to model 1. Model fits were evaluated, multi-group analyses were carried out and average variance extracted (AVE) and composite reliability (CR) estimates were examined. In this general population sample, low risk sample models 1 and 2 showed similar good overall...

  11. Selection of asset investment models by hospitals: examination of influencing factors, using Switzerland as an example.

    Science.gov (United States)

    Eicher, Bernhard

    2016-10-01

    Hospitals are responsible for a remarkable part of the annual increase in healthcare expenditure. This article examines one of the major cost drivers, the expenditure for investment in hospital assets. The study, conducted in Switzerland, identifies factors that influence hospitals' investment decisions. A suggestion on how to categorize asset investment models is presented based on the life cycle of an asset, and its influencing factors defined based on transaction cost economics. The influence of five factors (human asset specificity, physical asset specificity, uncertainty, bargaining power, and privacy of ownership) on the selection of an asset investment model is examined using a two-step fuzzy-set Qualitative Comparative Analysis. The research shows that outsourcing-oriented asset investment models are particularly favored in the presence of two combinations of influencing factors: First, if technological uncertainty is high and both human asset specificity and bargaining power of a hospital are low. Second, if assets are very specific, technological uncertainty is high and there is a private hospital with low bargaining power, outsourcing-oriented asset investment models are favored too. Using Qualitative Comparative Analysis, it can be demonstrated that investment decisions of hospitals do not depend on isolated influencing factors but on a combination of factors. Copyright © 2016 John Wiley & Sons, Ltd.

  12. Structured oral examination in pharmacology for undergraduate medical students: Factors influencing its implementation.

    Science.gov (United States)

    Khilnani, Ajeet Kumar; Charan, Jaykaran; Thaddanee, Rekha; Pathak, Rakesh R; Makwana, Sohil; Khilnani, Gurudas

    2015-01-01

    The study aims to understand the process and factors influencing the implementation of structured oral examination (SOE) for undergraduate medical students; in comparison with conventional oral examination (COE) in pharmacology. In a randomized, parallel group study, 123 students of pharmacology were divided into two groups, SOE (n = 63) and COE (n = 60). Students of each group were subdivided into two, and four examiners took viva voce individually. Three sets of questionnaires from autonomic nervous system were prepared, each having 15 items with increasing difficulty levels and were validated by subject experts and pretested. Ten minutes were allotted for each student for each viva. Feedback of students and faculty about the novel method was obtained. SOE yielded significantly lower marks as compared to COE. There were significant inter-examiner variations in marks awarded in SOE and COE. Other factors influencing implementation were difficulty in structuring viva, rigid time limits, lack of flexibility in knowledge content, monotony, and fatigue. The students perceived this format not different from COE but felt that it required in-depth preparation of topic. Faculty opined that SOE led to less drift from main topic and provided uniform coverage of topics in given time. Conducting SOE is a resource-intensive exercise. Despite structuring, inter-examiner variability was not completely eliminated. The students' performance was depended on factors related to examiners such as teaching experience, vernacular language used, and lack of training. Orientation and training of examiners in assessment strategies is necessary. Standardization of questionnaire is necessary before the implementation of SOE for summative assessment.

  13. Examining problem solving skills of physical education and sport students from several factors.

    Science.gov (United States)

    Tasgin, Ozden

    2011-06-01

    In this research, problem solving skills of university students are examined in the factors of sex and class. In this research problem solving inventory that is improved by Heppner and Petersen (1982) is applied to the students that are training 1. and 4. class 58 female 86 male at Selcuk University Konya, Turkey Physical Education and Sport Collage. In statistical analysis of research for the factors sex and class, variance analysis and t test are used. In the research while meaningful difference is found in the above dimension of the factors sex and there is not found meaningful difference in the factors of class. In conclusion, female students have more positive problem solving skills than male students.

  14. Factors shaping e-feedback utilization following electronic Objective Structured Clinical Examinations.

    Science.gov (United States)

    Ashby, Samantha E; Snodgrass, Suzanne H; Rivett, Darren A; Russell, Trevor

    2016-09-01

    The development of student-practitioners' practical clinical skills is essential in health professional education. Objective Structured Clinical Examinations are central to the assessment of students performing clinical procedures on simulated patients (actors). While feedback is considered core to learning providing timely, individualised student OSCE feedback is difficult. This study explored the perceptions of students about the multiple factors which shape the utility of e-feedback following an electronic Objective Structured Clinical Examinations, which utilized iPad and specialised software. The e-feedback was trialled in four courses within occupational therapy and physiotherapy pre-professional programs with a cohort of 204 students. Evaluation of student perceptions about feedback was collected using two surveys and eight focus groups. This data showed three factors shaped perceptions of the utility of e- Objective Structured Clinical Examinations feedback: 1) timely accessibility within one day of the assessment, 2) feedback demonstrating examiners' academic literacy and 3) feedback orientated to ways of improving future performance of clinical skills. The study found training in the provision of feedback using IPads and software is needed for examiners to ensure e-feedback meets students' needs for specific, future-oriented e-feedback and institutional requirements for justification of grades.

  15. Examination of factor structure for the consumers' responses to the Value Consciousness Scale.

    Science.gov (United States)

    Conrad, C A; Williams, J R

    2000-12-01

    The psychometric properties of the Value Consciousness Scale developed by Lichtenstein, Netemeyer, and Burton in 1990 were examined in a retail grocery study (N = 497). Original assessment of scale properties was undertaken using two convenience samples in a nonretail setting and additional scale performance has been documented by the scale authors. This study furthers previous research by (1) examining performance on the items in the retail grocery setting and (2) utilizing an appropriately rigorous sampling procedure. A confirmatory factor analysis indicated that the Value Consciousness Scale does not exhibit unidimensional properties, and one must be cautious if this scale is used in applications of market segmentation until further clarification can be provided.

  16. Factor structure of DSM-5 PTSD symptoms in trauma-exposed adolescents: Examining stability across time.

    Science.gov (United States)

    Wang, Li; Cao, Xing; Cao, Chengqi; Fang, Ruojiao; Yang, Haibo; Elhai, Jon D

    2017-07-23

    This study investigated the latent structure of DSM-5 PTSD symptoms using two-wave longitudinal data collected from a sample of adolescents exposed to an explosion accident. Two waves of surveys were conducted approximately 3 and 8 months after the accident, respectively. A total of 836 students completed the baseline survey, and 762 students completed the follow-up survey. The results of confirmatory factor analyses(CFA) indicated that a seven-factor hybrid model composed of intrusion, avoidance, negative affect, anhedonia, externalizing behaviors, anxious arousal and dysphoric arousal factors yielded significantly better data fit at both waves than the other models including the DSM-5 four-factor model, the six-factor anhedonia and externalizing behaviors models. Furthermore, the results of CFA invariance tests supported the longitudinal invariance of the model. Implications and limitations in terms of these results are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. The Benefits of Including Clinical Factors in Rectal Normal Tissue Complication Probability Modeling After Radiotherapy for Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Defraene, Gilles, E-mail: gilles.defraene@uzleuven.be [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Van den Bergh, Laura [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Al-Mamgani, Abrahim [Department of Radiation Oncology, Erasmus Medical Center - Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Haustermans, Karin [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Heemsbergen, Wilma [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands); Van den Heuvel, Frank [Radiation Oncology Department, University Hospitals Leuven, Leuven (Belgium); Lebesque, Joos V. [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam (Netherlands)

    2012-03-01

    Purpose: To study the impact of clinical predisposing factors on rectal normal tissue complication probability modeling using the updated results of the Dutch prostate dose-escalation trial. Methods and Materials: Toxicity data of 512 patients (conformally treated to 68 Gy [n = 284] and 78 Gy [n = 228]) with complete follow-up at 3 years after radiotherapy were studied. Scored end points were rectal bleeding, high stool frequency, and fecal incontinence. Two traditional dose-based models (Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) and a logistic model were fitted using a maximum likelihood approach. Furthermore, these model fits were improved by including the most significant clinical factors. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminating ability of all fits. Results: Including clinical factors significantly increased the predictive power of the models for all end points. In the optimal LKB, RS, and logistic models for rectal bleeding and fecal incontinence, the first significant (p = 0.011-0.013) clinical factor was 'previous abdominal surgery.' As second significant (p = 0.012-0.016) factor, 'cardiac history' was included in all three rectal bleeding fits, whereas including 'diabetes' was significant (p = 0.039-0.048) in fecal incontinence modeling but only in the LKB and logistic models. High stool frequency fits only benefitted significantly (p = 0.003-0.006) from the inclusion of the baseline toxicity score. For all models rectal bleeding fits had the highest AUC (0.77) where it was 0.63 and 0.68 for high stool frequency and fecal incontinence, respectively. LKB and logistic model fits resulted in similar values for the volume parameter. The steepness parameter was somewhat higher in the logistic model, also resulting in a slightly lower D{sub 50}. Anal wall DVHs were used for fecal incontinence, whereas anorectal wall dose best described the other two endpoints

  18. Examining the Factor Structure of Anxiety and Depression Symptom Items Among Adolescents in Santiago, Chile.

    Science.gov (United States)

    Bares, Cristina B; Andrade, Fernando; Delva, Jorge; Grogan-Kaylor, Andrew

    2011-01-01

    The co-occurrence of emotional disorders among adolescents has received considerable empirical attention. This study aims to contribute to the understanding of co-occurring anxiety and depression by examining the factor structure of the Youth Self-Report used with a sample of low-income adolescents from Santiago, Chile. Data from two independent, randomly selected subsamples were analyzed using exploratory and confirmatory factor analyses. Results indicate the best fit for the data is a two-factor model of anxiety and depression symptoms, which factors anxiety and depression into separate latent constructs. Because the findings show that anxiety and depression are not measured by the same factor in this international sample, the results imply that a valid and useful distinction exists between these constructs. That these constructs are found to be separate factors suggests that anxiety and depression may have separate etiologies and consequences, which might be best addressed by separate intervention components. These findings are consistent with the viewpoint that anxiety and depression constructs have similar emotional features and, despite sharing a common underlying internalizing disorder, distinct items capture aspects of each construct.

  19. Examining the factor structures of the five facet mindfulness questionnaire and the self-compassion scale.

    Science.gov (United States)

    Williams, Matthew J; Dalgleish, Tim; Karl, Anke; Kuyken, Willem

    2014-06-01

    The five facet mindfulness questionnaire (FFMQ; Baer, Smith, Hopkins, Krietemeyer, & Toney, 2006) and the self-compassion scale (SCS; Neff, 2003) are widely used measures of mindfulness and self-compassion in mindfulness-based intervention research. The psychometric properties of the FFMQ and the SCS need to be independently replicated in community samples and relevant clinical samples to support their use. Our primary aim was to establish the factor structures of the FFMQ and SCS in individuals with recurrent depression in remission, since mindfulness-based cognitive therapy (MBCT) was developed as a treatment for preventing depressive relapse. In order to determine the consistency across populations, we examined the factor structures of the FFMQ and SCS in 3 samples: (1) a convenience sample of adults, (2) a sample of adults who practice meditation, and (3) a sample of adults who suffer from recurrent depression and were recruited to take part in a trial of MBCT. Confirmatory factor analyses (CFAs) showed that a 4-factor hierarchical model of the FFMQ best fits the community sample and the clinical sample but that a 5-factor hierarchical model of the FFMQ best fits the meditator sample. CFA did not endorse the SCS 6-factor hierarchical structure in any of the 3 samples. Clinicians and researchers should be aware of the psychometric properties of the FFMQ to measure mindfulness when comparing meditators and nonmeditators. Further research is needed to develop a more psychometrically robust measure of self-compassion.

  20. Examining Factors Affecting Science Achievement of Hong Kong in PISA 2006 Using Hierarchical Linear Modeling

    Science.gov (United States)

    Lam, Terence Yuk Ping; Lau, Kwok Chi

    2014-10-01

    This study uses hierarchical linear modeling to examine the influence of a range of factors on the science performances of Hong Kong students in PISA 2006. Hong Kong has been consistently ranked highly in international science assessments, such as Programme for International Student Assessment and Trends in International Mathematics and Science Study; therefore, an exploration of the factors that affect science performances of Hong Kong students can give a lens to examine how science education can be improved in Hong Kong and other countries. The analyses reveal that student backgrounds as male, at higher grade levels, and born in mainland (when in the same grade) are associated with better science performance. Among the attitudinal factors, enjoyment of science and self-efficacy in science play important roles in scientific achievements. Most of the parental factors, on the other hand, are not having significant impacts on achievement after student attitudes are taken into account, with only parents' value of science having a small effect. School student intake is found to be a strong predictor of school average achievement, as well as a major mediator of the effects of school enrollment size and school socio-economic status. The findings differ from recently reported results, which suggested that school enrollment size was associated with achievement. This study also points out the problems of the use of science instruction time as a school-level variable to explain science achievement in Hong Kong.

  1. An Auditing Approach for ERP Systems Examining Human Factors that Influence ERP User Satisfaction

    Directory of Open Access Journals (Sweden)

    Theodoros MITAKOS

    2010-01-01

    Full Text Available This paper tries to connect the successful implementation and operation of the ERP (Enterprise Resource Planning information systems with people and their characteristics through a pilot survey. It examines the human factors that influence ERP user satisfaction. The presented survey tests 14 hypotheses and is based on the model developed by Zviran, Pliskin & Levin [21]. An additional factor has been added to the specified model, the self-efficacy factor analyzed by Bandura [1]. The results are based on 250 ERP users that responded to the survey. The key findings that were revealed by data analysis were that none of the human socio-demographic characteristics do influence ERP user satisfaction. Additionally it was found that perceived usefulness and self-efficacy are the key directors of the ERP user satisfaction. Moreover suggestions are given about how the companies should handle ERP usage in order to develop the prerequisites for increasing user satisfaction and productivity accordingly.

  2. Factors influencing the decision to participate in medical premarital examinations in Hubei Province, Mid-China.

    Science.gov (United States)

    Wang, Peigang; Wang, Xiao; Fang, Min; Vander Weele, Tyler J

    2013-03-11

    To investigate the attitudes of premarital couples towards the premarital screening program after the abolition of compulsory screening in China and to study the factors influencing participation. Between July 1st 2010 to August 31st 2010, 650 people who registered for marriage at the civil affairs bureau of Wuhan, Suizhou, Zaoyang in Hubei province were studied using questionnaires. Logistic regression was used to examine the factors influencing participation in the premarital screening program. The premarital screening rate was 34.8% (95% Confidence Interval: 31.0% to 38.5%). Several demographic factors (age, residence, profession), awareness, knowledge, and attitudes towards premarital screening all had significant influence on participation in the premarital screening program. Promotion activities and health education to improve knowledge and attitudes to premarital screening will help increase the rate of voluntary premarital screening.

  3. OSD’s Obligation & Expenditure Rate Goals: An Examination of the Factors Contributing to the Interference

    Science.gov (United States)

    2015-04-30

    Delays (F24) fell below x while four factors rose above x: Shortage of Cost Estimators (F29), Shortage of Business and Finance Management Personnel (F30...ååì~ä=^Åèìáëáíáçå= oÉëÉ~êÅÜ=póãéçëáìã= qÜìêëÇ~ó=pÉëëáçåë= sçäìãÉ=ff= = OSD’s Obligation & Expenditure Rate Goals: An Examination of the Factors ...the Factors Contributing to the Interference 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

  4. Examining the Factors Associated with Paid Employment of Clients Enrolled in First Episode of Psychosis Programs

    Directory of Open Access Journals (Sweden)

    Carolyn S. Dewa

    2012-01-01

    Full Text Available Schizophrenia is one of the most debilitating mental disorders. For a significant portion of individuals who suffer from this disorder, onset occurs in young adulthood, arresting important social and educational development that is necessary for future successful labor force participation. The purpose of this paper is to contribute to the literature about clients enrolled in first episode psychosis programs and psychosocial outcomes by examining the factors associated with paid employment among young adults who have experienced their first psychotic episodes. In this paper, we consider the association of socioeconomic factors to employment. Our results suggest that in addition to treatment, socioeconomic factors such as receipt of public disability benefits and educational attainment are associated with employment status. These results can help to inform future directions for the enhancement of psychosocial programs in FEP models to promote paid employment.

  5. Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

    Science.gov (United States)

    Nagaishi, Kanna; Mizue, Yuka; Chikenji, Takako; Otani, Miho; Nakano, Masako; Konari, Naoto; Fujimiya, Mineko

    2016-01-01

    Bone marrow-derived mesenchymal stem cells (MSCs) have contributed to the improvement of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not been characterized thoroughly. We investigated the effects of MSC therapy on DN, focusing on the paracrine effect of renal trophic factors, including exosomes secreted by MSCs. MSCs and MSC-conditioned medium (MSC-CM) as renal trophic factors were administered in parallel to high-fat diet (HFD)-induced type 2 diabetic mice and streptozotocin (STZ)-induced insulin-deficient diabetic mice. Both therapies showed approximately equivalent curative effects, as each inhibited the exacerbation of albuminuria. They also suppressed the excessive infiltration of BMDCs into the kidney by regulating the expression of the adhesion molecule ICAM-1. Proinflammatory cytokine expression (e.g., TNF-α) and fibrosis in tubular interstitium were inhibited. TGF-β1 expression was down-regulated and tight junction protein expression (e.g., ZO-1) was maintained, which sequentially suppressed the epithelial-to-mesenchymal transition of tubular epithelial cells (TECs). Exosomes purified from MSC-CM exerted an anti-apoptotic effect and protected tight junction structure in TECs. The increase of glomerular mesangium substrate was inhibited in HFD-diabetic mice. MSC therapy is a promising tool to prevent DN via the paracrine effect of renal trophic factors including exosomes due to its multifactorial action. PMID:27721418

  6. Examining the role of psychological factors in the relationship between sleep problems and suicide.

    Science.gov (United States)

    Littlewood, D; Kyle, S D; Pratt, D; Peters, S; Gooding, P

    2017-06-01

    We sought to conduct the first systematic review of empirical evidence investigating the role of psychological factors in the relationship between sleep problems and suicidal thoughts and behaviours. Twelve studies were identified which examined psychological factors grouped into four categories of cognitive appraisals, psychosocial factors, emotion regulation strategies, and risk behaviours. Although there was substantial heterogeneity across studies with respect to measurement, sampling, and analysis, preliminary evidence indicated that negative cognitive appraisals, perceived social isolation, and unhelpful emotion regulation strategies may contribute to the association between sleep problems and suicidal thoughts and behaviours. Given that findings in this area are currently restricted to studies with cross-sectional designs, the directionality of the interrelationships between these psychological factors, sleep problems and suicidality, remains unclear. We integrate the findings of our review with contemporary psychological models of suicidal behaviour to develop a clear research agenda. Identified pathways should now be tested with longitudinal and experimental designs. In addition, a more thorough investigation of the complexities of sleep, psychological factors, and suicidal thoughts and behaviours is crucial for the development of targeted psychological interventions. Copyright © 2017. Published by Elsevier Ltd.

  7. Negative Mood and Obsessive-Compulsive Related Clinical Constructs: An Examination of Underlying Factors

    Directory of Open Access Journals (Sweden)

    Gary I. Britton

    2017-09-01

    Full Text Available Emerging evidence suggests that many of the clinical constructs used to help understand and explain obsessive-compulsive (OC symptoms, and negative mood, may be causally interrelated. One approach to understanding this interrelatedness is a motivational systems approach. This approach suggests that rather than considering clinical constructs and negative affect as separable entities, they are all features of an integrated threat management system, and as such are highly coordinated and interdependent. The aim of the present study was to examine if clinical constructs related to OC symptoms and negative mood are best treated as separable or, alternatively, if these clinical constructs and negative mood are best seen as indicators of an underlying superordinate variable, as would be predicted by a motivational systems approach. A sample of 370 student participants completed measures of mood and the clinical constructs of inflated responsibility, intolerance of uncertainty, not just right experiences, and checking stop rules. An exploratory factor analysis suggested two plausible factor structures, one where all construct items and negative mood items loaded onto one underlying superordinate variable, and a second structure comprising of five factors, where each item loaded onto a factor representative of what the item was originally intended to measure. A confirmatory factor analysis showed that the five factor model was preferential to the one factor model, suggesting the four constructs and negative mood are best conceptualized as separate variables. Given the predictions of a motivational systems approach were not supported in the current study, other possible explanations for the causal interrelatedness between clinical constructs and negative mood are discussed.

  8. EXAMINING FACTORS IN FLUENCING CUSTOMER SATISFACTION AND TRUST TOWARDS VENDORS ON THE MOBILE INTERNET

    Directory of Open Access Journals (Sweden)

    Norazah Mohd Suki

    2012-04-01

    Full Text Available This study aims to examine factors influencing customer satisfaction and trust towards vendors on the mobile Internet. Data were analysed among 200 respondents who completed the questionnaire by employing multiple regression analysis. Results revealed that customer satisfaction towards the vendor was significantly influenced by ease-of-use, responsiveness, and brand image. Meanwhile, customer trust towards the vendor in m-commerce is affected by responsiveness, brand image and satisfaction towards the vendor in m-commerce. The findings imply there is a need for a vendor in m-commerce to put greater focus on the factors that can generate more satisfaction and trust from the customers. The paper rounds off with conclusions and an agenda for future research in this area

  9. Analysis of Factors That Affects the Capital Structure within Companies Included In the Index of LQ45 During 2011 - 2013

    Directory of Open Access Journals (Sweden)

    Dominica Rufina

    2016-01-01

    Full Text Available This study aims to determine the factors of ROA, Asset Structure, Sales Growth, and Firm Size affecting Capital Structure. The population in this study is the companies included in the Index LQ45 Indonesia Stock Exchange from the period 2011 to 2013, the data of a total of 270 listed companies in LQ45 during that period, only 90 corporate data that successively included in the index LQ45. The data used in this study uses secondary data from the Indonesia Stock Exchange website www.idx.co.id. In the process of data analysis and testing the assumptions of classical hypothesis testing using multiple linear regression analysis using SPSS v20.00. The results showed that partially variable ROA, Asset Structure, and Firm Size has a significant influence on the Capital Structure, Growth Sales whereas variable has no influence on the Capital Structure. Simultaneously ROA, Asset Structure, Sales Growth, and Firm Size effect on Capital Structure.

  10. The effect of urbanization on ant abundance and diversity: a temporal examination of factors affecting biodiversity.

    Directory of Open Access Journals (Sweden)

    Grzegorz Buczkowski

    Full Text Available Numerous studies have examined the effect of urbanization on species richness and most studies implicate urbanization as the major cause of biodiversity loss. However, no study has identified an explicit connection between urbanization and biodiversity loss as the impact of urbanization is typically inferred indirectly by comparing species diversity along urban-rural gradients at a single time point. A different approach is to focus on the temporal rather than the spatial aspect and perform "before and after" studies where species diversity is cataloged over time in the same sites. The current study examined changes in ant abundance and diversity associated with the conversion of natural habitats into urban habitats. Ant abundance and diversity were tracked in forested sites that became urbanized through construction and were examined at 3 time points - before, during, and after construction. On average, 4.3 ± 1.2 unique species were detected in undisturbed plots prior to construction. Ant diversity decreased to 0.7 ± 0.8 species in plots undergoing construction and 1.5 ± 1.1 species in plots 1 year after construction was completed. With regard to species richness, urbanization resulted in the permanent loss of 17 of the 20 species initially present in the study plots. Recovery was slow and only 3 species were present right after construction was completed and 4 species were present 1 year after construction was completed. The second objective examined ant fauna recovery in developed residential lots based on time since construction, neighboring habitat quality, pesticide inputs, and the presence of invasive ants. Ant diversity was positively correlated with factors that promoted ecological recovery and negatively correlated with factors that promoted ecological degradation. Taken together, these results address a critical gap in our knowledge by characterizing the short- and long-term the effects of urbanization on the loss of ant

  11. Postnatal visual deprivation in rats regulates several retinal genes and proteins, including differentiation-associated fibroblast growth factor-2.

    Science.gov (United States)

    Prokosch-Willing, Verena; Meyer zu Hoerste, Melissa; Mertsch, Sonja; Stupp, Tobias; Thanos, Solon

    2015-01-01

    Little is known about the retinal cellular basis of amblyopia, which is a developmental disease characterized by impaired visual acuity. This study examined the retinal transcripts associated with experimentally induced unilateral amblyopia in rats. Surgical tarsorrhaphy of the eyelids on one side was performed in pups prior to eye opening at postnatal day 14, thereby preventing any visual experience. This condition was maintained for over 2 months, after which electroretinograms (ERGs) were recorded, the retinal ganglion cell (RGC) arrangement and number were determined using neuroanatomical tracing, the retinal transcripts were studied using microarray analysis, regulated mRNAs were confirmed with quantitative reverse-transcriptase PCR, and proteins were stained using Western blotting and immunohistochemistry. An attenuated ERG was found in eyes that were deprived of visual experience. Retrograde neuroanatomical staining disclosed a larger number of RGCs within the retina on the visually deprived side compared to the non-deprived, control side, and a multilayered distribution of RGCs. At the retinomic level, several transcripts associated with retinal differentiation, such as fibroblast growth factor 2 (FGF-2), were either up- or downregulated. Most of the transcripts could be verified at the mRNA level. To unravel the role of a differentiation-associated protein, we tested FGF-2 in dissociated postnatal retinal cell cultures and found that FGF-2 is a potent factor triggering ganglion cell differentiation. The data suggest that visual experience shapes the postnatal retinal differentiation, whereas visual deprivation induces changes at the functional, cellular and molecular levels within the retina.

  12. Examining the Factor Structure of the Positive and Negative Affect Schedule (PANAS) in a Multiethnic Sample of Adolescents

    Science.gov (United States)

    Villodas, Feion; Villodas, Miguel T.; Roesch, Scott

    2011-01-01

    The psychometric properties of the Positive and Negative Affect Schedule were examined in a multiethnic sample of adolescents. Results from confirmatory factor analyses indicated that the original two-factor model did not adequately fit the data. Exploratory factor analyses revealed that four items were not pure markers of the factors. (Contains 1…

  13. An expert performance approach to examining factors contributing to academic success in organic chemistry

    Science.gov (United States)

    Nandagopal, Kiruthiga

    Successful completion of the introductory course in organic chemistry is a prerequisite for many graduate and professional science programs, yet the failure rate for this course is notoriously high. To date, there have been few studies examining factors contributing to academic success in organic chemistry. This study demonstrates that the online, longitudinal methods used by investigations of expert performance can examine and successfully identify factors contributing to academic success at the college level. Sixty-four students enrolled in introductory organic chemistry during the Fall 2007 and Spring 2008 semesters completed motivation questionnaires, interviews, diaries, and think-aloud reading and problem-solving tasks at three different points across a semester. Measures of spatial ability, general ability, and background preparation were also collected. Each measure was analyzed to determine significant differences between groups differing in grade-point average (GPA) prior to the start of the course and to identify predictors of organic chemistry grade. Variables measuring background preparation, problem-solving strategies and studying strategies were found to be the best predictors of academic success in organic chemistry. Implications for instruction in organic chemistry and effective studying behaviors are discussed.

  14. Best-fit model of exploratory and confirmatory factor analysis of the 2010 Medical Council of Canada Qualifying Examination Part I clinical decision-making cases.

    Science.gov (United States)

    Champlain, André F De

    2015-01-01

    This study aims to assess the fit of a number of exploratory and confirmatory factor analysis models to the 2010 Medical Council of Canada Qualifying Examination Part I (MCCQE1) clinical decision-making (CDM) cases. The outcomes of this study have important implications for a range of domains, including scoring and test development. The examinees included all first-time Canadian medical graduates and international medical graduates who took the MCCQE1 in spring or fall 2010. The fit of one- to five-factor exploratory models was assessed for the item response matrix of the 2010 CDM cases. Five confirmatory factor analytic models were also examined with the same CDM response matrix. The structural equation modeling software program Mplus was used for all analyses. Out of the five exploratory factor analytic models that were evaluated, a three-factor model provided the best fit. Factor 1 loaded on three medicine cases, two obstetrics and gynecology cases, and two orthopedic surgery cases. Factor 2 corresponded to pediatrics, and the third factor loaded on psychiatry cases. Among the five confirmatory factor analysis models examined in this study, three- and four-factor lifespan period models and the five-factor discipline models provided the best fit. The results suggest that knowledge of broad disciplinary domains best account for performance on CDM cases. In test development, particular effort should be placed on developing CDM cases according to broad discipline and patient age domains; CDM testlets should be assembled largely using the criteria of discipline and age.

  15. Examining influential factors in providers' chronic pain treatment decisions: a comparison of physicians and medical students.

    Science.gov (United States)

    Hollingshead, Nicole A; Meints, Samantha; Middleton, Stephanie K; Free, Charnelle A; Hirsh, Adam T

    2015-10-01

    Chronic pain treatment guidelines are unclear and conflicting, which contributes to inconsistent pain care. In order to improve pain care, it is important to understand the various factors that providers rely on to make treatment decisions. The purpose of this study was to examine factors that reportedly influence providers' chronic pain treatment decisions. A secondary aim was to examine differences across participant training level. Eighty-five participants (35 medical students, 50 physicians) made treatment decisions for 16 computer-simulated patients with chronic pain. Participants then selected from provided lists the information they used and the information they would have used (had it been available) to make their chronic pain treatment decisions for the patient vignettes. Frequency analyses indicated that most participants reported using patients' pain histories (97.6 %) and pain description (95.3 %) when making treatment decisions, and they would have used information about patients' previous treatments (97.6 %) and average and current pain ratings (96.5 %) had this information been available. Compared to physicians, medical students endorsed more frequently that they would have used patients' employment and/or disability status (p medical students wanted information on patients' use of illicit drugs and alcohol to make treatment decisions; while a greater proportion of physicians reported using personal experience to inform their decisions. This study found providers use patients' information and their own experiences and intuition to make chronic pain treatment decisions. Also, participants of different training levels report using different patient and personal factors to guide their treatment decisions. These results highlight the complexity of chronic pain care and suggest a need for more chronic pain education aimed at medical students and practicing providers.

  16. Examining the relationship between school district size and science achievement in Texas including rural school administrator perceptions of challenges and solutions

    Science.gov (United States)

    Mann, Matthew James

    Rural and small schools have almost one-third of all public school enrollment in America, yet typically have the fewest financial and research based resources. Educational models have been developed with either the urban or suburban school in mind, and the rural school is often left with no other alternative except this paradigm. Rural based educational resources are rare and the ability to access these resources for rural school districts almost non-existent. Federal and state based education agencies provide some rural educational based programs, but have had virtually no success in answering rural school issues. With federal and state interest in science initiatives, the challenge that rural schools face weigh in. To align with that focus, this study examined Texas middle school student achievement in science and its relationship with school district enrollment size. This study involved a sequential transformative mixed methodology with the quantitative phase driving the second qualitative portion. The quantitative research was a non-experimental causal-comparative study conducted to determine whether there is a significant difference between student achievement on the 2010 Texas Assessment of Knowledge and Skills 8 th grade science results and school district enrollment size. The school districts were distributed into four categories by size including: a) small districts (32-550); b) medium districts (551-1500); c) large districts (1501-6000); and d) mega-sized districts (6001-202,773). A one-way analysis of variance (ANOVA) was conducted to compare the district averages from the 2010 TAKS 8th grade science assessment results and the four district enrollment groups. The second phase of the study was qualitative utilizing constructivism and critical theory to identify the issues facing rural and small school administrators concerning science based curriculum and development. These themes and issues were sought through a case study method and through use of semi

  17. Five-year examination of utilization and drug cost outcomes associated with benefit design changes including reference pricing for proton pump inhibitors in a state employee health plan.

    Science.gov (United States)

    Johnson, Jill T; Neill, Kathryn K; Davis, Dwight A

    2011-04-01

    The Arkansas State Employee Benefits Division (EBD) is a self-insured program comprising public school and other state employees, their spouses, and dependents. Previous research published in JMCP (2006) showed drug cost savings of $2.20 per member per month (PMPM; 37.6%) or annualized savings of $3.4 million associated with a benefit design change and coverage of the proton pump inhibitor (PPI) omeprazole over-the-counter (OTC) beginning in March 2004. On May 1, 2005, brand esomeprazole was excluded from coverage, with current users grandfathered for 4 months until September 2005. Reference pricing for PPIs, including esomeprazole but excluding generic omeprazole, was implemented on September 1, 2005, and the beneficiary cost share for all PPIs except generic omeprazole was determined from comparison of the PPI actual price to the $0.90 omeprazole OTC reference price per unit. To examine PPI utilization and drug costs before and after (a) excluding esomeprazole from coverage (with grandfathering current users) and (b) implementing a therapeutic maximum allowable cost (TMAC), or reference-pricing benefit design, for the PPI class in a large state employee health plan with fairly stable enrollment of approximately 127,500 members in 2005 through 2008 and approximately 128,000 members in 2009 Q1. The pharmacy claims database for the EBD was used to examine utilization and cost data for PPIs in a longitudinal analysis for the 61-month period from March 1, 2004, through March 31, 2009. Pharmacy claims data were compared for the period 14 months prior to esomeprazole exclusion (preperiod), 4 months during the esomeprazole exclusion (postperiod 1), and the ensuing 43 months of PPI reference pricing (postperiod 2). PPI cost and utilization data for the intervention group of approximately 127,500 beneficiaries were compared with a group of 122 self-insured employers with a total of nearly 1 million beneficiaries whose pharmacy benefits did not include reference pricing for

  18. Examination of Turkish extreme athletes' personality traits in terms of gender and some demographic factors

    Directory of Open Access Journals (Sweden)

    Merve Ceylan

    2015-09-01

    Full Text Available The present study was conducted for the purpose of examining the personality traits of extreme athletes. In line with this purpose a total of 227 extreme athletes, as 86 female and 141 male athletes selected through judgment sampling, that either actively compete or trains to compete in any of the branches of snowboarding, snowkiting, kitesurfing, windsurfing, river kayaking, mountain biking, free diving, paragliding and rafting were included within the sample group of the study. Questionnaire applications were carried out in extreme sports facilities throughout the country. Within the scope of the study, an 85-item short form of the Five Factor Personality Scale developed by Somer, Korkmaz and Tatar was used as the data collection tool. Data analysis was carried out by means of the SPSS 16.0 software and the percentages frequencies, mean, standard deviation and to find the differences between the sexes "independent t" test were calculated. Examining the obtained results showed that the male athletes have higher extravertion level from female athletes (p <0.05. This finding obtained in our study suggest that, in an essentially male-dominant society, the higher level of pressure women are subjected to in social, economic, cultural and psychological terms and the difficulties and pressure they experience in the working life are significant factors for women to be more introvert.     Özet Bu araştırma, ekstrem sporcuların kişilik özelliklerinin incelemesi amacıyla yapılmıştır. Bu amaç doğrultusunda araştırmaya, yargısal örnekleme yöntemiyle seçilmiş, snowboard, snowkite, uçurtma sörfü, rüzgar sörfü, akarsu ve nehir kanosu, dağ bisikleti, serbest dalış, yamaç paraşütü, kaya tırmanışı ve rafting branşlarında yarışmacı olan ya da bir yarışmaya katılmak için hazırlık yapan, 86’sı kadın, 141’i erkek olmak üzere 227 ekstrem sporcu katılmıştır.  Anket uygulamaları, ülke genelinde bulunan

  19. Using avian radar to examine relationships among avian activity, bird strikes, and meteorological factors

    Science.gov (United States)

    Coates, Peter S.; Casazza, Michael L.; Halstead, Brian J.; Fleskes, Joseph P.; Laughlin, James A.

    2011-01-01

    Radar systems designed to detect avian activity at airfields are useful in understanding factors that influence the risk of bird and aircraft collisions (bird strikes). We used an avian radar system to measure avian activity at Beale Air Force Base, California, USA, during 2008 and 2009. We conducted a 2-part analysis to examine relationships among avian activity, bird strikes, and meteorological and time-dependent factors. We found that avian activity around the airfield was greater at times when bird strikes occurred than on average using a permutation resampling technique. Second, we developed generalized linear mixed models of an avian activity index (AAI). Variation in AAI was first explained by seasons that were based on average migration dates of birds at the study area. We then modeled AAI by those seasons to further explain variation by meteorological factors and daily light levels within a 24-hour period. In general, avian activity increased with decreased temperature, wind, visibility, precipitation, and increased humidity and cloud cover. These effects differed by season. For example, during the spring bird migration period, most avian activity occurred before sunrise at twilight hours on clear days with low winds, whereas during fall migration, substantial activity occurred after sunrise, and birds generally were more active at lower temperatures. We report parameter estimates (i.e., constants and coefficients) averaged across models and a relatively simple calculation for safety officers and wildlife managers to predict AAI and the relative risk of bird strike based on time, date, and meteorological values. We validated model predictability and assessed model fit. These analyses will be useful for general inference of avian activity and risk assessment efforts. Further investigation and ongoing data collection will refine these inference models and improve our understanding of factors that influence avian activity, which is necessary to inform

  20. PTSD symptomatology and hazardous drinking as risk factors for sexual assault revictimization: examination in European American and African American women.

    Science.gov (United States)

    Littleton, Heather; Ullman, Sarah E

    2013-06-01

    A sexual victimization history is a risk factor for experiencing further sexual victimization. Posttraumatic stress disorder (PTSD) symptoms have been posited as predictors of revictimization through multiple pathways, including through their association with risk recognition and alcohol use. There is, however, limited longitudinal research examining these revictimization risk factors, including the extent to which they predict risk for forcible rape (rape involving threat or force) and incapacitated rape (rape of a victim incapacitated by substances). Additionally, there is no research evaluating ethnic differences in revictimization risk pathways. The current study examined PTSD symptoms and hazardous drinking as predictors of new forcible and incapacitated rape over 1 year in a community sample of European American (n = 217) and African American (n = 272) sexual assault victims (M = 34 years; 84% high school education or above). We hypothesized that PTSD symptoms would predict both types of revictimization and hazardous drinking would predict incapacitated rape. Results supported that PTSD symptoms predicted both types of rape (forcible rape, β = .34; incapacitated rape, β = .20), and hazardous drinking predicted incapacitated rape (β = .24). PTSD symptoms predicted hazardous drinking in African American women only (β = .20). Thus, there is a need to evaluate risk pathways for specific types of victimization among diverse samples.

  1. A new prognostic model for cancer-specific survival after radical cystectomy including pretreatment thrombocytosis and standard pathological risk factors.

    Science.gov (United States)

    Todenhöfer, Tilman; Renninger, Markus; Schwentner, Christian; Stenzl, Arnulf; Gakis, Georgios

    2012-12-01

    Study Type - Prognosis (cohort series) Level of Evidence 2a What's known on the subject? and What does the study add? Preoperative thrombocytosis has been identified as a predictor of poor outcome in various cancer types. However, the prognostic role of platelet count in patients with invasive bladder cancer undergoing radical cystectomy is unknown. The present study demonstrates that preoperative thrombocytosis is an independent risk factor for decreased cancer-specific survival after radical treatment of invasive bladder cancer. We developed a new prognostic scoring model for cancer-specific outcomes after radical cystectomy including platelet count and established pathological risk factors. Consideration of platelet count in the final model increased its predictive accuracy significantly. Thrombocytosis may be a useful parameter to include within established international bladder cancer nomograms. •  To investigate the oncological significance of preoperative thrombocytosis in patients with invasive bladder cancer undergoing radical cystectomy, as it has been reported as a marker for aggressive tumour biology in a variety of solid tumours. •  The series comprised 258 patients undergoing radical cystectomy between 1999 and 2010 in whom different clinical and histopathological parameters were assessed. •  Elevated platelet count was defined as >450 × 10(9) /L. •  Based on regression estimates of significant parameters in multivariable analysis a new weighted scoring model was developed to predict cancer-specific outcomes. •  The median follow-up was 30 months (6-116). •  Of the 258 patients, 26 (10.1%) had elevated and 232 (89.9%) had normal platelet count. The 3-year cancer-specific survival in patients with normal and elevated platelet count was 61.5% and 32.7%, respectively (P thrombocytosis (2.68, 1.26-5.14; P= 0.011). •  The 3-year cancer-specific survival in patients with a score 0 (low risk), 1-2 (intermediate risk) and 3

  2. Patient size and x-ray technique factors in head computed tomography examinations. I. Radiation doses.

    Science.gov (United States)

    Huda, Walter; Lieberman, Kristin A; Chang, Jack; Roskopf, Marsha L

    2004-03-01

    We investigated how patient age, size and composition, together with the choice of x-ray technique factors, affect radiation doses in head computed tomography (CT) examinations. Head size dimensions, cross-sectional areas, and mean Hounsfield unit (HU) values were obtained from head CT images of 127 patients. For radiation dosimetry purposes patients were modeled as uniform cylinders of water. Dose computations were performed for 18 x 7 mm sections, scanned at a constant 340 mAs, for x-ray tube voltages ranging from 80 to 140 kV. Values of mean section dose, energy imparted, and effective dose were computed for patients ranging from the newborn to adults. There was a rapid growth of head size over the first two years, followed by a more modest increase of head size until the age of 18 or so. Newborns have a mean HU value of about 50 that monotonically increases with age over the first two decades of life. Average adult A-P and lateral dimensions were 186+/-8 mm and 147+/-8 mm, respectively, with an average HU value of 209+/-40. An infant head was found to be equivalent to a water cylinder with a radius of approximately 60 mm, whereas an adult head had an equivalent radius 50% greater. Adult males head dimensions are about 5% larger than for females, and their average x-ray attenuation is approximately 20 HU greater. For adult examinations performed at 120 kV, typical values were 32 mGy for the mean section dose, 105 mJ for the total energy imparted, and 0.64 mSv for the effective dose. Increasing the x-ray tube voltage from 80 to 140 kV increases patient doses by about a factor of 5. For the same technique factors, mean section doses in infants are 35% higher than in adults. Energy imparted for adults is 50% higher than for infants, but infant effective doses are four times higher than for adults. CT doses need to take into account patient age, head size, and composition as well as the selected x-ray technique factors.

  3. CE: Original Research: Examining the Links Between Lifestyle Factors and Metabolic Syndrome.

    Science.gov (United States)

    Chang, Shu-Hung; Chen, Miao-Chuan; Chien, Nai-Hui; Wu, Li-Yu

    2016-12-01

    : Background: As it is in many other developed countries, obesity is a growing health concern in Taiwan, affecting nearly 20% of the adult population. Obesity can increase the risk of developing metabolic syndrome, diabetes, and cardiovascular disease. Recent data indicate that the prevalence of metabolic syndrome in Taiwan is 25.5%. Yet some overweight and obese individuals have normal metabolic profiles. It's not clear why some overweight or obese people remain metabolically healthy while others do not. The purpose of this study was to examine lifestyle risk factors for metabolic syndrome in people who are overweight or obese. We were particularly interested in distinguishing those lifestyle factors associated with metabolic health in this population. Data collected from community-based physical examinations in northern Taiwan were used for this cross-sectional study. A survey was conducted from 2013 to 2014. We collected data on demographic variables, clinically pertinent measures (weight; height; waist circumference; blood pressure; and levels of fasting blood glucose, triglycerides, and high-density lipoprotein cholesterol), and lifestyle factors (smoking, drinking, exercise, and dietary habits). To analyze the data, we used percentage, mean, standard deviation, χ test, independent t test, the Fisher exact test, phi correlation, and logistic regression. The overall prevalence of metabolic syndrome among all 734 participants was 36.4%. For the normal weight, overweight, and obese groups, the prevalence of metabolic syndrome was 12.4%, 36.4%, and 61.6%, respectively. The results of logistic regression showed, however, that obese individuals who exercised regularly and ate sufficient amounts of fruit were less likely to have metabolic syndrome, and that overweight individuals who were nonsmokers and ate sufficient amounts of vegetables were also less likely to have metabolic syndrome. Lifestyle factors may significantly affect the development of metabolic

  4. Examination for a viral co-factor in postweaning multisystemic wasting syndrome (PMWS)

    DEFF Research Database (Denmark)

    Lohse, Louise; Bøtner, Anette; Hansen, Anne-Sofie Ladekjær

    2008-01-01

    In order to test the hypothesis that a putative co-factor for the development of postweaning multisystemic wasting syndrome (PMWS) in pigs could be of viral origin, we performed extensive virological examinations on organ material from pigs diagnosed with PMWS originating from within a Danish PMWS...... from four PMWS-affected herds, four PMWS-positive pigs plus one unaffected herd. The PCV2 genomes from the two groups showed 95.5% identity. Alignment analyses of the sequences encoding the replicase and capsid protein from group 1 and group 2 PCV2 isolates showed two amino acid differences encoded...... in the replicase protein, while 19 amino acid differences were predicted among the capsid protein sequences. The PCV2 DNA sequence analysis supports recent observations from studies in USA as well as Europe, which suggest that strain variations may influence the clinical outcome of PCV2 infection....

  5. Baseline Examination Factors Associated With Clinical Improvement After Dry Needling in Individuals With Low Back Pain.

    Science.gov (United States)

    Koppenhaver, Shane L; Walker, Michael J; Smith, Ryan W; Booker, Jacquelynn M; Walkup, Isaac D; Su, Jonathan; Hebert, Jeffrey J; Flynn, Timothy

    2015-08-01

    Quasi-experimental. To explore for associations between demographic, patient history, and physical examination variables and short-term improvement in self-reported disability following dry needling therapy performed on individuals with low back pain (LBP). Dry needling is an intervention used with increasing frequency in patients with LBP; however, the characteristics of patients who are most likely to respond are not known. Seventy-two volunteers with mechanical LBP participated in the study. Potential prognostic factors were collected from baseline questionnaires, patient history, and physical examination tests. Treatment consisted of dry needling to the lumbar multifidus muscles bilaterally, administered during a single treatment session. Improvement was based on percent change on the Oswestry Disability Index at 1 week. The univariate and multivariate associations between 33 potential prognostic factors and improved disability were assessed with correlation coefficients and multivariate linear regression. Increased LBP with the multifidus lift test (rpb = 0.31, P = .01) or during passive hip flexion performed with the patient supine (rpb = 0.23, P = .06), as well as positive beliefs about acupuncture/dry needling (rho = 0.22, P = .07), demonstrated univariate associations with Oswestry Disability Index improvement. Aggravation of LBP with standing (rpb = -0.27, P = .03), presence of leg pain (rpb = -0.29, P = .02), and any perception of hypermobility in the lumbar spine (rpb = -0.21, P = .09) were associated with less improvement. The multivariate model identified 2 predictors of improved disability with dry needling: pain with the multifidus lift test and no aggravation with standing (R(2) = 0.16, P = .01). Increased LBP with the multifidus lift test was the strongest predictor of improved disability after dry needling, suggesting that the finding of pain during muscle contraction should be studied in future dry needling studies. Prognosis, level 1b.

  6. Examining How Media Literacy and Personality Factors Predict Skepticism Toward Alcohol Advertising.

    Science.gov (United States)

    Austin, Erica Weintraub; Muldrow, Adrienne; Austin, Bruce W

    2016-05-01

    To examine the potential effectiveness of media literacy education in the context of well-established personality factors, a survey of 472 young adults, focused on the issue of alcohol marketing messages, examined how individual differences in personality associate with constructs representing aspects of media literacy. The results showed that need for cognition predicted social expectancies and wishful identification with media portrayals in alcohol advertising only through critical thinking about media sources and media content, which are foci of media literacy education. Need for affect did not associate with increased or diminished levels of critical thinking. Critical thinking about sources and messages affected skepticism, represented by expectancies through wishful identification, consistent with the message interpretation process model. The results support the view that critical thinking about media sources is an important precursor to critical thinking about media messages. The results also suggest that critical thinking about media (i.e., media literacy) reflects more than personality characteristics and can affect wishful identification with role models observed in media, which appears to be a key influence on decision making. This adds support to the view that media literacy education can improve decision making across personality types regarding alcohol use by decreasing the potential influence of alcohol marketing messages.

  7. Prevalence of Abnormity of Blood Lipid and Associated Factors in Health Examination Population in Beijing

    Institute of Scientific and Technical Information of China (English)

    Wei-ming Kang; Jie-shi Zhang; Xin-xin Liu; Min-shan Wang; Ming-li Zhao; Jian-chun Yu

    2009-01-01

    Objective To investigate the prevalence of abnormity of blood lipid and associated factors in healthy population in Beijing.Methods Totally,38462 individuals who received health examination were enrolled in our study.We divided them into eight groups according to their ages.The levels of serum total cholesterol,triglyceride,high density lipoprotein cholesterol,and low density lipoprotein cholesterol were tested,and the relationship of blood lipid abnormity with body mass index(BMI)and fasting blood glucose was analyzed.Results The incidences of hypercholesterolemia,hyperglyceridemia,low high-density lipoprotein cholesterolemia,and hyper low-density lipoprotein cholesterolemia presented increasing trend in this population.The incidence rate of abnormity of blood lipid in health examination population increased with BMI increase.The incidence of abnormity of blood lipid in overweight and obesity population was significantly higher than that in low weight and normal weight populations(P<0.05).Meanwhile,the trend of abnormal blood lipid incidence coincided with that of abnormal fasting blood glucose.Conclusions The prevalence of overweight,obesity,and abnormity of blood lipid in Beijing presents increasing trend.The incidence of abnormity of blood lipid increases with BMI increase,in coincidence with that of fasting blood glucose.

  8. Gender and Middle School Science: An Examination of Intrinsic and Extrinsic Factors Affecting Achievement

    Science.gov (United States)

    Austin, Jennifer

    Gender differences in middle school science were examined utilizing a mixed-methods approach. The intrinsic and extrinsic experiences of male and female non-gifted high-achieving students were investigated through the administration of the CAIMI, student interviews, teacher questionnaires, observations, and document examination. Male and female students were selected from a rural Northeast Georgia school district based on their high performance and high growth during middle school science. Eighty-three percent of the student participants were white and 17% were Hispanic. Half of the male participants and one third of the female participants were eligible for free and reduced meals. Findings revealed that male participants were highly motivated, whereas female participants exhibited varying levels of motivation in science. Both male and female students identified similar instructional strategies as external factors that were beneficial to their success. Due to their selection by both genders, these instructional strategies were considered to be gender-neutral and thereby useful for inclusion within coeducational middle school science classrooms.

  9. Practices of Breast Self-Examination and Associated Factors among Female Debre Berhan University Students.

    Science.gov (United States)

    Birhane, Kalayu; Alemayehu, Miskir; Anawte, Belayneh; Gebremariyam, Gebru; Daniel, Ruth; Addis, Semeneh; Worke, Teshome; Mohammed, Abdurrahman; Negash, Wassie

    2017-01-01

    Breast cancer is the most prevalent form of cancer in Ethiopia of all female cancers. It is considered to be a progressive disease with a poor prognosis if detected late. Breast self-examination is an important prevention method of breast cancer. This study was aimed at assessing practice and associated factors of breast self-examination (BSE) among female Debre Berhan University students in Ethiopia. A cross-sectional study was conducted in 2015 among 420 using self-administrated questionnaire. Multistage sampling technique was used to select the study participants. Bivariate and multivariate logistic regression analysis were done. Majority of the study participants, 338 (84.5%), were between 20 and 24 years old with the mean age of 21.1 ± 1.65. Only 14 (3.5%) had family history of breast cancer. Two hundred fifty-six (64%) of the participants had heard about BSE and 30.25% had good knowledge about BSE. Mass media were the most common source of information about breast cancer. Few of the participants (28.3%) had performed BSE. Lack of knowledge on how to perform BSE was cited as the main reason for not practicing BSE. Knowing how to perform, when to perform, and position to perform BSE and having a perception that BSE is important and useful to detect breast cancer were significant predictors of practices of BSE. This study revealed that most of the participants had low knowledge and practice of BSE. Therefore, it important to develop health educational programs in the university to raise awareness about BSE and breast cancer so as to practice self-breast examination.

  10. [Structural analysis for psychosocial factors including health locus of control (HLC) and sense of coherence (SOC) associated with lifestyle-related diseases].

    Science.gov (United States)

    Ogawa, Y; Nakamura, H; Nagase, H; Ogino, K; Ooshita, Y; Tsukahara, S

    2001-01-01

    The purpose of this study was to clarify psychosocial characteristics associated with preventive health behavior for lifestyle-related diseases. The author performed objective health examinations and gave questionnaires to 289 men (39.7 +/- 11.8 years, mean +/- SD) and 80 women (32.8 +/- 10.4 years) engaged in office work. Psychosocial factors included lifestyle and perceived stress, as well as the health locus of control (HLC) and sense of coherence (SOC) as newly developed indicators for health behavior. The principal component analysis for men did not extract lifestyle from the psychosocial structures. Multiple regression analysis showed that internal HLC (IHLC), chance HLC (CHLC), professional HLC (PHLC) and stress significantly contributed to SOC. Principal component analysis using psychosocial factors in women showed two psychosocial structures, i.e. the second principal (high SOC, high lifestyle, and low stress) and the 4th principal components (high supernatural HLC, and high PHLC). Both components were negatively correlated with systolic blood pressure. SOC was recognized to be negatively associated with age, stress, and total cholesterol, and positively with IHLC, FHLC, lifestyle, and gamma-GTP using multiple regression analysis for women. These results indicated a distinguishable sex difference regarding the involvement of psychosocial factors including HLC and SOC in objective health. SOC seems likely to be involved not in objective health, but closely with stress, suggesting a direct influence on mental health. Lifestyle should be divided into more detailed categories such as smoking and salt intake. Structural analysis of women suggests that SOC is involved directly or indirectly through lifestyle in objective health, different from men. To further clarify causal relationships between psychosocial factors and risk factors for lifestyle-related diseases, a longitudinal study is necessary based on these results.

  11. Collapsing Factors in Multitrait-Multimethod Models: Examining Consequences of a Mismatch Between Measurement Design and Model

    Directory of Open Access Journals (Sweden)

    Christian eGeiser

    2015-08-01

    Full Text Available Models of confirmatory factor analysis (CFA are frequently applied to examine the convergent validity of scores obtained from multiple raters or methods in so-called multitrait-multimethod (MTMM investigations. Many applications of CFA-MTMM and similarly structured models result in solutions in which at least one method (or specific factor shows non-significant loading or variance estimates. Eid et al. (2008 distinguished between MTMM measurement designs with interchangeable (randomly selected versus structurally different (fixed methods and showed that each type of measurement design implies specific CFA-MTMM measurement models. In the current study, we hypothesized that some of the problems that are commonly seen in applications of CFA-MTMM models may be due to a mismatch between the underlying measurement design and fitted models. Using simulations, we found that models with M method factors (where M is the total number of methods and unconstrained loadings led to a higher proportion of solutions in which at least one method factor became empirically unstable when these models were fit to data generated from structurally different methods. The simulations also revealed that commonly used model goodness-of-fit criteria frequently failed to identify incorrectly specified CFA-MTMM models. We discuss implications of these findings for other complex CFA models in which similar issues occur, including nested (bifactor and latent state-trait models.

  12. Collapsing factors in multitrait-multimethod models: examining consequences of a mismatch between measurement design and model

    Science.gov (United States)

    Geiser, Christian; Bishop, Jacob; Lockhart, Ginger

    2015-01-01

    Models of confirmatory factor analysis (CFA) are frequently applied to examine the convergent validity of scores obtained from multiple raters or methods in so-called multitrait-multimethod (MTMM) investigations. Many applications of CFA-MTMM and similarly structured models result in solutions in which at least one method (or specific) factor shows non-significant loading or variance estimates. Eid et al. (2008) distinguished between MTMM measurement designs with interchangeable (randomly selected) vs. structurally different (fixed) methods and showed that each type of measurement design implies specific CFA-MTMM measurement models. In the current study, we hypothesized that some of the problems that are commonly seen in applications of CFA-MTMM models may be due to a mismatch between the underlying measurement design and fitted models. Using simulations, we found that models with M method factors (where M is the total number of methods) and unconstrained loadings led to a higher proportion of solutions in which at least one method factor became empirically unstable when these models were fit to data generated from structurally different methods. The simulations also revealed that commonly used model goodness-of-fit criteria frequently failed to identify incorrectly specified CFA-MTMM models. We discuss implications of these findings for other complex CFA models in which similar issues occur, including nested (bifactor) and latent state-trait models. PMID:26283977

  13. Program Factors That Influence American Board of Surgery In-Training Examination Performance: A Multi-Institutional Study.

    Science.gov (United States)

    Kim, Jerry J; Gifford, Edward D; Moazzez, Ashkan; Sidwell, Richard A; Reeves, Mark E; Hartranft, Thomas H; Inaba, Kenji; Jarman, Benjamin T; Are, Chandrakanth; Galante, Joseph M; Amersi, Farin; Smith, Brian R; Melcher, Marc L; Nelson, M Timothy; Donahue, Timothy; Jacobsen, Garth; Arnell, Tracey D; Lee, Steven; Neville, Angela; de Virgilio, Christian

    2015-01-01

    To determine the influence of program strategies, such as program directors' (PD) attitudes about the American Board of Surgery In-Training Examination (ABSITE) and approach to ABSITE preparation, on residents' ABSITE performance. A 17-item questionnaire was sent to PDs at surgical residency programs. The questions were designed to elicit information regarding the educational curriculum, remediation protocols, and opinions relating to the ABSITE. Main outcome measure was categorical resident ABSITE percentile scores from the January 2014 examination. Statistical analysis was performed using the Student t-test, analysis of variance, and linear regression as appropriate. The study was carried out at general surgery residency programs across the country. In total, 15 general surgery residency PDs participated in the study. The PD response rate was 100%. All 460 resident ABSITE scores from the 15 programs were obtained. In total, 10 programs (67%) identified as university affiliated, 4 programs (27%) as independent academic, and 1 program (7%) as hybrid. The mean number of residents per program was 30.7 (range: 15-57). In total, 14 PDs (93%) indicated that an ABSITE review curriculum was in place and 13 PDs (87%) indicated they had a remediation protocol for residents with low ABSITE scores (with differing thresholds of factors associated with higher ABSITE scores included tracking resident reading throughout the year (median 63rd percentile with tracking vs 59th percentile without, p = 0.040) and the type of remediation (by PD: 77th percentile, by PD and faculty: 57th percentile, faculty only: 64th percentile, with Surgical Education and Self-Assessment Program (SESAP): 63rd percentile, outside review course: 43rd percentile; p Factors not significantly associated with ABSITE performance included number of structured educational hours per week and frequency of ABSITE review sessions. Program factors appear to significantly influence ABSITE performance. Programs where

  14. A phase II clinical study to assess the feasibility of self and partner anal examinations to detect anal canal abnormalities including anal cancer.

    Science.gov (United States)

    Nyitray, Alan G; Hicks, Joseph T; Hwang, Lu-Yu; Baraniuk, Sarah; White, Margaret; Millas, Stefanos; Onwuka, Nkechi; Zhang, Xiaotao; Brown, Eric L; Ross, Michael W; Chiao, Elizabeth Y

    2017-08-23

    Anal cancer is a common cancer among men who have sex with men (MSM); however, there is no standard screening protocol for anal cancer. We conducted a phase II clinical trial to assess the feasibility of teaching MSM to recognise palpable masses in the anal canal which is a common sign of anal cancer in men. A clinician skilled in performing digital anorectal examinations (DARE) used a pelvic manikin to train 200 MSM, aged 27-78 years, how to do a self-anal examination (SAE) for singles or a partner anal examination (PAE) for couples. The clinician then performed a DARE without immediately disclosing results, after which the man or couple performed an SAE or PAE, respectively. Percentage agreement with the clinician DARE in addition to sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for the SAE, PAE and overall. Men had a median age of 52 years, 42.5% were African American and 60.5% were HIV positive. DARE detected abnormalities in 12 men while the men's SAE/PAEs detected 9 of these. A total of 93.0% of men classified the health of their anal canal correctly (95% CI 89.5 to 96.5). Overall percentage agreement, sensitivity and specificity were 93.0%, 75.0% and 94.2%, respectively, while PPV and NPV were 45.0% and 98.3%, respectively. The six men who detected the abnormality had nodules/masses ≥3 mm in size. More than half of men (60.5%) reported never checking their anus for an abnormality; however, after performing an SAE/PAE, 93.0% said they would repeat it in the future. These results suggest that tumours of ≥3 mm may be detectable by self or partner palpation among MSM and encourage further investigation given literature suggesting a high cure rate for anal cancer tumours ≤10 mm. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Examination of central body fat deposition as a risk factor for loss-of-control eating.

    Science.gov (United States)

    Berner, Laura A; Arigo, Danielle; Mayer, Laurel Es; Sarwer, David B; Lowe, Michael R

    2015-10-01

    Elevated body mass index (BMI), higher waist-to-hip ratio, and body dissatisfaction have been investigated as risk factors for the development of bulimic symptoms. Central fat deposition may be particularly relevant to eating disorders. To our knowledge, the longitudinal relations between fat distribution, body dissatisfaction, and loss-of-control (LOC) eating development and maintenance have not been studied. We examined body fat distribution, independent of BMI and depressive symptoms, as a unique correlate and predictor of body dissatisfaction and LOC eating cross-sectionally and over a 2-y follow-up. Body composition was measured by using dual-energy X-ray absorptiometry in 294 adult women at risk of weight gain at baseline, 6 mo, and 24 mo. We assessed LOC eating, body dissatisfaction, and depressive symptoms at baseline, 6 wk, 6 mo, 12 mo, and 24 mo by using the Eating Disorder Diagnostic Interview, the Multidimensional Body-Self Relations Questionnaire-Appearance Scales Body Areas Satisfaction subscale, and the Center for Epidemiologic Studies-Depression Scale, respectively. Independent of BMI, baseline total percentage body fat, percentage trunk fat, and percentage abdominal fat were related to greater body dissatisfaction. Total percentage body fat and trunk fat tended to be associated with greater body dissatisfaction at all subsequent time points. Women with a greater percentage trunk fat, specifically abdominal fat, were at highest risk of developing LOC eating. In the full sample, women with higher baseline percentage trunk and abdominal fat showed increases in LOC eating episode frequency over time, whereas LOC eating frequency remained stable among women with smaller percentages of fat in trunk and abdominal regions. These findings lend further support to the premise that increased central body fat deposition is associated with body image dissatisfaction and suggest that it may represent a risk and maintenance factor for LOC eating. This trial was

  16. Central nervous system involvement in human immunodeficiency virus disease. A prospective study including neurological examination, computerized tomography, and magnetic resonance imaging

    DEFF Research Database (Denmark)

    Pedersen, C; Thomsen, C; Arlien-Søborg, P;

    1991-01-01

    Sixty-seven patients with different stages of human immunodeficiency virus (HIV) infection (47 CDC group IV, 20 CDC groups II or III) were followed prospectively for a median of 18 months with neurological examination, magnetic resonance imaging (MRI), and computerized tomography (CT) to evaluate...... the incidence of the AIDS dementia complex (CDC definition) and other neurological complications. Ten patients developed CNS opportunistic infection or malignancy. Among the remaining 57 patients, 12 of 37 (32%) belonging to CDC group IV, and 1 of 20 (5%) belonging to CDC groups II/III developed the AIDS...... dementia complex (p = 0.03). MRI white matter lesions occurred in 32% of CDC group IV patients and 5% of CDC groups II/III patients (p = 0.03). The corresponding figures for brain atrophy at CT were 71% and 30% (p less than 0.01) and for neurologic signs 49% and 20% (p = 0.06). The development of the AIDS...

  17. Lifestyle modification induced weight loss and changes of cardiometabolic risk factors including lowering of inflammatory response in obese children.

    Science.gov (United States)

    Motykova, Eva; Zlatohlavek, Lukáš; Prusikova, Martina; Lanska, Vera; Ceska, Richard; Vasickova, Ludmila; Vrablik, Michal

    2011-01-01

    Obesity is associated with increased inflammation which represents a link to atherosclerosis and cardiovascular disease. Lipoprotein associated phospholipase A2 (Lp-PLA2) is an independent marker of inflammation and atherosclerosis risk. To assess the impact of weight loss on metabolic markers of atherosclerosis including Lp-PLA2 we examined a group of Czech non-diabetic obese/overweight children exposed to a lifestyle intervention. Fourty unrelated overweight/obese non-diabetic Czech children (13.7 ± 2.1 years, average BMI at baseline 29.8 ± 2.6 kg/m2) underwent 4 weeks of lifestyle modification (reduction of energy intake to age matched optimum and supervised physical activity). Anthropometrical and biochemical variables were determined at baseline and after the intervention. Lp-PLA2 mass concentration was assessed using the ELISA kit. Wilcocson's rank test and Spearman's correlation were used for statistical analysis. A significant decrease of BMI and waist circumference was associated with significant changes of plasma lipoprotein and glycaemia levels. Mass concentration of Lp-PLA2 at the baseline was 402 ± 94 μg/ml, after the intervention 368 ± 105 μg/ml (p=0.008). Change in Lp-PLA2 was associated with triglyceride level decrease (p=0.009). Intensive lifestyle modification leading to body weight decrease results in significant changes of plasma lipoprotein levels and, also, a drop of Lp-PLA2 levels in paediatric obese patients. However, even after the intervention Lp-PLA2 concentrations in this patient group remain elevated suggesting possible increased atherosclerosis risk in later life. © 2011 Neuroendocrinology Letters

  18. Examining the Interrelationship among Critical Success Factors of Public Private Partnership Infrastructure Projects

    Directory of Open Access Journals (Sweden)

    Shiying Shi

    2016-12-01

    Full Text Available Examining the interrelationships among critical success factors (CSFs for public private partnership (PPP projects is of importance for improving PPP project performance and maintaining the sustainability of PPP project implementation. Previous studies mostly focused on the identification of the CSFs for PPP projects; limited studies investigated the interrelationships among CSFs. Hence, the research objectives are (a to determine the interrelationships among CSFs of PPP projects taking into account the public and (b to identify influence paths contributing to take advantage of CSFs in the process of PPP implementation. A literature review and expert interviews were adopted to construct the CSFs framework; nine hypotheses were constructed and tested by the structural equation modelling (SEM based on the data collected from a questionnaire survey. This research reveals that the relationship between public and private partners is the leader-follower relationship, not the partnership relationship, in PPP projects, indicating that the responsibilities, power or resources existing among partners are very unequal. It also highlights that public involvement has a negative effect on the process of service provisions, and costs and risks exist in the process of public involvement in PPP projects. The determined interrelationships among CSFs will contribute to the sustainability and success of a PPP project.

  19. Examining Factors Influencing Internet Addiction and Adolescent Risk Behaviors Among Excessive Internet Users.

    Science.gov (United States)

    Jiang, Qiaolei; Huang, Xiuqin; Tao, Ran

    2017-08-29

    In China, public concern continues to mount regarding the risks of excessive Internet use among adolescents. This study investigated the factors influencing Internet addiction and adolescent risk behaviors among excessive Internet users. Proposing a conceptual model with a theoretical origin in risk behavior theory and media dependency theory, this study examined the influence of personality traits, online gaming, Internet connectedness (both the overall index and various scopes), and demographics on Internet addiction and risk behaviors (smoking, drinking, gambling, and risky sexual behaviors). Clinical data (N = 467) were retrieved from one of the earliest and largest Internet addiction clinics in China. The findings reveal that certain personality traits are significantly associated with Internet addiction and risk behaviors. Online gaming had a strong impact on both Internet addiction and risk behaviors among excessive Internet users. The study also reveals that various scopes of Internet connectedness, such as site scope, facilitate addictive Internet use, and risk behaviors among adolescents. The findings can contribute to the prevention of and intervention into Internet addiction and adolescent risk behaviors.

  20. Relationship between depression and loneliness in elderly and examination of influential factors.

    Science.gov (United States)

    Aylaz, Rukuye; Aktürk, Ümmühan; Erci, Behice; Öztürk, Hatice; Aslan, Hakime

    2012-01-01

    This study was planned and conducted for the purpose of examining the relationship between depression and loneliness in elderly people and the influencing factors. The study was a descriptive and correlational study and its population consisted of 17,080 older individuals aged sixty and over who were registered at six Family Healthcare Centers (FHCs) located in the provisional center of Malatya. The sample of the study comprised of 913 elderly people who were chosen from the elderly people registered at the FHCs first by cluster sampling and then by simple random sampling from the clusters in proportion to the population. The data was collected between April and June 2011 using a questionnaire developed by the investigators in line with the literature, the Geriatric Depression Scale (GDS) and the UCLA Loneliness Scale (ULS). They had a mean score of 13.83 ± 7.4 from the GDS and 40.50 ± 12.1 from the ULS. A positive correlation was found between Geriatric Depression and loneliness (r=0.608, ploneliness and depression in the elderly people living in a community, presence of social security and higher income, on the other hand, led to lower mean scores. In view of these results, it can be advised that a minimum income should be secured for elderly people whether they have social security or not, their families and the society should be trained not to leave elderly people alone.

  1. Association Between Serum Antibodies to Periodontal Bacteria and Rheumatoid Factor in the Third National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Goh, Charlene E; Kopp, Jacob; Papapanou, Panos N; Molitor, Jerry A; Demmer, Ryan T

    2016-10-01

    Alterations in the microbiome, including the periodontal microbiome, may be a risk factor for rheumatoid arthritis (RA). Most studies that have analyzed this association are relatively small, focus primarily on a single periodontal pathogen (Porphyromonas gingivalis), and are not population based. This study was undertaken to investigate the association between elevated serum levels of IgG antibodies to 19 periodontal species and the prevalence of rheumatoid factor (RF) in a large nationally representative sample of adults. The Third National Health and Nutrition Examination Survey (NHANES-III) is a cross-sectional sample of the noninstitutionalized US population (n = 33,994). Our study population included all dentate participants who were 60 years and older, did not have RA as defined by a modified version of the American College of Rheumatology 1987 criteria, and had complete data for both serum IgG antibodies against periodontal bacteria and serum RF antibody titer (n = 2,461). Adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) summarizing the relationship between the 19 periodontal serum IgG antibodies and RF seropositivity ranged from 0.53 (95% CI 0.29-0.97) to 1.27 (95% CI 0.79-2.06), and 17 of the 19 observed ORs were periodontal bacteria are mostly unassociated with RF seropositivity in the nationally representative NHANES-III. Elevated levels of antibodies to P intermedia and C ochracea are associated with lower odds of RF seropositivity. © 2016, American College of Rheumatology.

  2. What factors facilitate the engagement with flipped classrooms used in the preparation for postgraduate medical membership examinations?

    Directory of Open Access Journals (Sweden)

    Jesurasa A

    2017-06-01

    Full Text Available Amrita Jesurasa, Kelly Mackenzie, Hannah Jordan, Elizabeth C Goyder School of Health and Related Research (ScHARR, University of Sheffield, Regent Court, Sheffield, UK Background: The “flipped classroom,” a pedagogical model where typical lecture and homework elements are reversed, is being advocated in medical education to support the teaching of a large curriculum. However, research into the use of this model in postgraduate medical education, which requires the application of acquired knowledge, is limited. The aim of this study was to explore the barriers and facilitators to engagement with the flipped classroom model in preparation for the written element of postgraduate membership examinations. Methods: Three focus groups (n=14 were held between February and June 2016. Participants were drawn from a membership examination preparation course, run by the University of Sheffield. Two of the groups (n=10 involved “students” (public health registrars while the other focus group (n=4 was held with “tutors” (experienced registrars and consultants. The focus groups were audiorecorded and transcribed verbatim. Transcripts were thematically analyzed by using both predetermined and emergent themes. Results: Key themes that emerged from the data included variation in learning and teaching styles of individuals as well as the feasibility and flexibility of the overall course design. However, management of students’ expectations was found to be the fundamental factor, which underpinned the engagement. Conclusion: The complex interaction of factors affecting engagement in this study highlights the need to consider the appropriateness of the flipped classroom model. However, this must be balanced by the potential benefits of the approach for delivering a large curriculum. Recognizing the central importance of managing expectations at the outset would be useful when considering this model in postgraduate medical education. Keywords

  3. An examination of the relationship between personality and aggression using the general aggression and five factor models.

    Science.gov (United States)

    Hosie, Julia; Gilbert, Flora; Simpson, Katrina; Daffern, Michael

    2014-01-01

    This study examined the relationships between personality and aggression using the general aggression (GAM, Anderson and Bushman [2002] Annual Review of Psychology, 53, 27-51) and five factor models (FFMs) (Costa and McCrae [1992] Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) professional manual. Odessa, FL: Psychological Assessment Resources). Specifically, it examined Ferguson and Dyck's (Ferguson and Dyck [2012] Aggression and Violent Behavior, 17, 220-228) criticisms that the GAM has questionable validity in clinical populations and disproportionately focuses on aggression-related knowledge structures to the detriment of other inputs, specifically personality variables. Fifty-five male offenders attending a community forensic mental health service for pre-sentence psychiatric and/or psychological evaluation were assessed for aggressive script rehearsal, aggression-supportive normative beliefs, FFM personality traits, trait anger and past aggressive behavior. With regard to relationships between five factor variables and aggression, results suggested that only agreeableness and conscientiousness were related to aggression. However, these relationships were: (1) weak in comparison with those between script rehearsal, normative beliefs and trait anger with aggression and (2) were not significant predictors in hierarchical regression analysis when all of the significant univariate predictors, including GAM-specified variables were regressed onto life history of aggression; normative beliefs supporting aggression, aggressive script rehearsal, and trait anger were significantly related to aggression in this regression analysis. These results provide further support for the application of the GAM to aggressive populations. © 2013 Wiley Periodicals, Inc.

  4. Positive youth development among African American adolescents: examining single parents as a factor.

    Science.gov (United States)

    Roberts, Shani R; Lewis, Rhonda K; Carmack, Chakema

    2011-01-01

    Over the past few decades researchers have begun to examine the importance of understanding positive youth development and the many contexts in which youth find themselves. The social contexts in which adolescent development occurs are varied and complex, particularly the development among African American youth. African American youth are faced with a number of challenges including living in single-parent homes, high teen pregnancy rates, and poor neighborhoods, yet many of these youth continue to thrive. The purpose of this study was to examine the relationship between family structure (single-parenting) and adolescent outcomes such as educational aspirations and sexual activity among African American adolescent youth aged 12-17. Approximately 462 African American youth were surveyed. A number of positive results emerged; for instance, there was a negative correlation between family structure and educational aspirations. The number of parents in the home did not interfere with youth wanting to complete high school and go on to college (r = - .218, r² = .04, p < .05). The results also showed that as educational aspirations increased, the number of sexual partners decreased (r = - .141, meaning that the more adolescents reported a desire to complete high school, they were less likely to report having sexual intercourse. These positive results should be promoted among African American youth so that those faced with these challenges will note that others have overcome and accomplished their goals. In this population educational aspirations were important. Limitations and future research are discussed.

  5. Examining the factor structure and convergent and discriminant validity of the Levenson self-report psychopathy scale: is the two-factor model the best fitting model?

    Science.gov (United States)

    Salekin, Randall T; Chen, Debra R; Sellbom, Martin; Lester, Whitney S; MacDougall, Emily

    2014-07-01

    The Levenson, Kiehl, and Fitzpatrick (1995) Self-Report Psychopathy Scale (LSRP) was introduced in the mid-1990s as a brief measure of psychopathy and has since gained considerable popularity. Despite its attractiveness as a brief psychopathy tool, the LSRP has received limited research regarding its factor structure and convergent and discriminant validity. The present study examined the construct validity of the LSRP, testing both its factor structure and the convergent and discriminant validity. Using a community sample of 1,257 undergraduates (869 females; 378 males), we tested whether a 1-, 2-, or 3-factor model best fit the data and examined the links between the resultant factor structures and external correlates. Confirmatory factor analysis (CFA) findings revealed a 3-factor model best matched the data, followed by an adequate-fitting original 2-factor model. Next, comparisons were made regarding the convergent and discriminant validity of the competing 2- and 3-factor models. Findings showed the LSRP traditional primary and secondary factors had meaningful relations with extratest variables such as neuroticism, stress tolerance, and lack of empathy. The 3-factor model showed particular problems with the Callousness scale. These findings underscore the importance of examining not only CFA fit statistics but also convergent and discriminant validity when testing factor structure models. The current findings suggest that the 2-factor model might still be the best way to interpret the LSRP. (c) 2014 APA, all rights reserved.

  6. Hydrogeomorphic Classification of Wetlands on Mt. Desert Island, Maine, Including Hydrologic Susceptibility Factors for Wetlands in Acadia National Park

    Science.gov (United States)

    Nielsen, Martha G.

    2006-01-01

    The U.S. Geological Survey, in cooperation with the National Park Service, developed a hydrogeomorphic (HGM) classification system for wetlands greater than 0.4 hectares (ha) on Mt. Desert Island, Maine, and applied this classification using map-scale data to more than 1,200 mapped wetland units on the island. In addition, two hydrologic susceptibility factors were defined for a subset of these wetlands, using 11 variables derived from landscape-scale characteristics of the catchment areas of these wetlands. The hydrologic susceptibility factors, one related to the potential hydrologic pathways for contaminants and the other to the susceptibility of wetlands to disruptions in water supply from projected future changes in climate, were used to indicate which wetlands (greater than 1 ha) in Acadia National Park (ANP) may warrant further investigation or monitoring. The HGM classification system consists of 13 categories: Riverine-Upper Perennial, Riverine-Nonperennial, Riverine- Tidal, Depressional-Closed, Depressional-Semiclosed, Depressional-Open, Depressional-No Ground-Water Input, Mineral Soil Flat, Organic Soil Flat, Tidal Fringe, Lacustrine Fringe, Slope, and Hilltop/Upper Hillslope. A dichotomous key was developed to aid in the classification of wetlands. The National Wetland Inventory maps produced by the U.S. Fish and Wildlife Service provided the wetland mapping units used for this classification. On the basis of topographic map information and geographic information system (GIS) layers at a scale of 1:24,000 or larger, 1,202 wetland units were assigned a preliminary HGM classification. Two of the 13 HGM classes (Riverine-Tidal and Depressional-No Ground-Water Input) were not assigned to any wetlands because criteria for determining those classes are not available at that map scale, and must be determined by more site-specific information. Of the 1,202 wetland polygons classified, which cover 1,830 ha in ANP, 327 were classified as Slope, 258 were

  7. Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study.

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    Giustino Parruti

    Full Text Available BACKGROUND: Psychological factors are known predictors of cardiovascular disease in many clinical settings, but data are lacking for HIV infection. We carried out a prospective cohort study to evaluate potential psychological predictors of preclinical and clinical vascular disease in HIV patients. METHODOLOGY/PRINCIPAL FINDINGS: HIV patients were consecutively enrolled. Demographics, viral and immune parameters and traditional cardiovascular predictors were considered; Intima-Media Thickness (c-IMT, continuous measure and Carotid Plaques (CPs, focal thickening ≥1.5 mm were investigated by B-mode ultrasonography; depressive symptoms by the Beck Depression Inventory (BDI-II, Type D personality (Distressed Personality or Type D by the DS14, alexithymia by the Toronto Alexithymia Scale (TAS-20. Vascular outcomes included transient ischemic attacks or stroke, acute coronary syndrome, myocardial or other organ infarction. We enrolled 232 HIV subjects, 73.9% males, aged 44.5±9.9 y, 38.2% with AIDS diagnosis, 18.3% untreated. Mean Nadir CD4 T-cell counts were 237.5±186.2/mmc. Of them, 224 (96.5% attended IMT measurements; 201 (86.6% attended both IMT assessment and psychological profiling. Mean follow-up was 782±308 days. Fifty-nine patients (29.4% had CPs at baseline. Nineteen patients (9.5% had ≥1 vascular event; 12 (6.0% died due to such events (n = 4 or any cause. At baseline cross-sectional multivariate analysis, increasing age, total cholesterol, current smoking and Alexithymia score≥50 were significantly associated with both increased cIMT (linear regression and CPs (logistic regression. At follow-up analysis, log-rank tests and Cox's regression revealed that only older age (p = 0.001, current smoking (p = 0.019 and alexithymia score≥50 (p = 0.013 were independently associated with vascular events. CONCLUSIONS/SIGNIFICANCE: In HIV-infected subjects, the Alexithymic trait emerges as a strong predictor of increased IMT, presence of CPs

  8. Comparison of approaches to Total Quality Management. Including an examination of the Department of Energy`s position on quality management

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, C.T.

    1994-03-01

    This paper presents a comparison of several qualitatively different approaches to Total Quality Management (TQM). The continuum ranges from management approaches that are primarily standards -- with specific guidelines, but few theoretical concepts -- to approaches that are primarily philosophical, with few specific guidelines. The approaches to TQM discussed in this paper include the International Organization for Standardization (ISO) 9000 Standard, the Malcolm Baldrige National Quality Award, Senge`s the Learning Organization, Watkins and Marsick`s approach to organizational learning, Covey`s Seven Habits of Highly Successful People, and Deming`s Fourteen Points for Management. Some of these approaches (Deming and ISO 9000) are then compared to the DOE`s official position on quality management and conduct of operations (DOE Orders 5700.6C and 5480.19). Using a tabular format, it is shown that while 5700.6C (Quality Assurance) maps well to many of the current approaches to TQM, DOE`s principle guide to management Order 5419.80 (Conduct of Operations) has many significant conflicts with some of the modern approaches to continuous quality improvement.

  9. Connections, Productivity and Funding: An Examination of Factors Influencing Scientists' Perspectives on the Market Orientation of Academic Research

    Science.gov (United States)

    Ronning, Emily Anne

    2012-01-01

    This study examines scientists' perceptions of the environment in which they do their work. Specifically, this study examines how academic and professional factors such as research productivity, funding levels for science, connections to industry, type of academic appointment, and funding sources influence scientists' perceptions of the…

  10. Examining the Factor Structure and Hierarchical Nature of the Quality of Life Construct

    Science.gov (United States)

    Wang, Mian; Schalock, Robert L.; Verdugo, Miguel A.; Jenaro, Christina

    2010-01-01

    There is considerable debate in the area of individual quality of life research regarding the factor structure and hierarchical nature of the quality of life construct. Our purpose in this study was to test via structural equation modeling an a priori quality of life model consisting of eight first-order factors and one second-order factor. Data…

  11. Examination of Gender Differences on Cognitive and Motivational Factors That Influence 8th Graders' Science Achievement in Turkey

    Science.gov (United States)

    Acar, Ömer; Türkmen, Lütfullah; Bilgin, Ahmet

    2015-01-01

    We examined the influence of several students' cognitive and motivational factors on 8th graders' science achievement and also gender differences on factors that significantly contribute to the science achievement model. A total of 99 girls and 83 boys responded all the instruments used in this study. Results showed that girls outperformed boys on…

  12. Examination of Gender Differences on Cognitive and Motivational Factors That Influence 8th Graders' Science Achievement in Turkey

    Science.gov (United States)

    Acar, Ömer; Türkmen, Lütfullah; Bilgin, Ahmet

    2015-01-01

    We examined the influence of several students' cognitive and motivational factors on 8th graders' science achievement and also gender differences on factors that significantly contribute to the science achievement model. A total of 99 girls and 83 boys responded all the instruments used in this study. Results showed that girls outperformed boys on…

  13. Best-fit model of exploratory and confirmatory factor analysis of the 2010 Medical Council of Canada Qualifying Examination Part I clinical decision-making cases

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    André F. De Champlain

    2015-04-01

    Full Text Available Purpose: This study aims to assess the fit of a number of exploratory and confirmatory factor analysis models to the 2010 Medical Council of Canada Qualifying Examination Part I (MCCQE1 clinical decision-making (CDM cases. The outcomes of this study have important implications for a range of domains, including scoring and test development. Methods: The examinees included all first-time Canadian medical graduates and international medical graduates who took the MCCQE1 in spring or fall 2010. The fit of one- to five-factor exploratory models was assessed for the item response matrix of the 2010 CDM cases. Five confirmatory factor analytic models were also examined with the same CDM response matrix. The structural equation modeling software program Mplus was used for all analyses. Results: Out of the five exploratory factor analytic models that were evaluated, a three-factor model provided the best fit. Factor 1 loaded on three medicine cases, two obstetrics and gynecology cases, and two orthopedic surgery cases. Factor 2 corresponded to pediatrics, and the third factor loaded on psychiatry cases. Among the five confirmatory factor analysis models examined in this study, three- and four-factor lifespan period models and the five-factor discipline models provided the best fit. Conclusion: The results suggest that knowledge of broad disciplinary domains best account for performance on CDM cases. In test development, particular effort should be placed on developing CDM cases according to broad discipline and patient age domains; CDM testlets should be assembled largely using the criteria of discipline and age.

  14. Predicting academic and National Board Dental Hygiene Examination performance based on Academic Factors.

    Science.gov (United States)

    Bauchmoyer, Susan M; Carr, Michele P; Clutter, Jill E; Hoberty, Phillip D

    2004-01-01

    Numerous studies have explored reliable variables that predict student success in dental hygiene programs and on the National Board Dental Hygiene Examination (NBDHE). However, no studies were found using data collected since the NBDHE format changed in 1998 to investigate if traditional predictors hold true. The objective of this study was to examine the relationship between pre-admission requirements, basic college science requirements, site of academic preparation, cumulative dental hygiene grade point average (CDHYGPA) and the NBDHE score. Data from the academic records of 173 graduates of the dental hygiene program at The Ohio State University from 1998 through 2002 were entered into an Excel spreadsheet using identification numbers. Demographic information for the description of the subjects, course transfer data, course grades in program prerequisites and basic science requirements, CDHYGPA, and NBDHE scores were entered. Data were analyzed using the Statistical Package for the Social sciences (SPSS-version 10), Pearson's r correlations, regression analysis, and ANOVA with a predetermined level of significance at .05. Of the 173 records entered, 132 had complete data (76.3%). Results indicate the existing prerequisites for the dental hygiene program remain strong predictors for success. A strong correlation was noted between human nutrition courses and the CDHYGPA. Other core science courses completed while in the program-anatomy, physiology and microbiology--also rendered a moderately strong correlation to the CDHYGPA. The greatest predictors for success on the NBDHE were the student's CDHYGPA and the prerequisite three science GPA. Consistency in site of science preparation also revealed a positive correlation to the CDHYGPA. This study confirmed the continued use of the three science GPA pre-requisite and entering GPA for predicting success in this dental hygiene program and on the NBDHE even after the format changed to include case-based items. Other

  15. Excitation and charge transfer in He/sup +/ + H collisions. A molecular approach including two-electron translation factors

    Energy Technology Data Exchange (ETDEWEB)

    Errea, L.F.; Mendez, L.; Riera, A.

    1983-06-01

    In a previous paper we have pointed out that the common-translation-factor (CTF) method is the only one which, at present, and within the framework of the molecular model of atomic collisions, can be shown to be both convergent and computationally fast, even for many-electron systems. In this Communication we check that this second statement is correct, presenting, for the first time, a molecular calculation involving two-electron translation factors, for He/sup +/ + H collisions. A careful study of the sensitivity of the calculated cross sections to the choice of the CTF is performed, and conclusions on that sensitivity are drawn, for several types of processes.

  16. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

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    O'Byrne Kenneth J

    2011-03-01

    Full Text Available Abstract Background Thromboxane synthase (TXS metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibition induces cell death in-vitro, providing a rationale for therapeutic intervention. We aimed to determine the expression profile of TXS in NSCLC and if it is prognostic and/or a survival factor in the disease. Methods TXS expression was examined in human NSCLC and matched controls by western analysis and IHC. TXS metabolite (TXB2 levels were measured by EIA. A 204-patient NSCLC TMA was stained for COX-2 and downstream TXS expression. TXS tissue expression was correlated with clinical parameters, including overall survival. Cell proliferation/survival and invasion was examined in NSCLC cells following both selective TXS inhibition and stable TXS over-expression. Results TXS was over-expressed in human NSCLC samples, relative to matched normal controls. TXS and TXB2 levels were increased in protein (p p p p Conclusion TXS is over-expressed in NSCLC, particularly in the adenocarcinoma subtype. Inhibition of this enzyme inhibits proliferation and induces apoptosis. Targeting thromboxane synthase alone, or in combination with conventional chemotherapy is a potential therapeutic strategy for NSCLC.

  17. Prevalence and risk factors for refractive errors: Korean National Health and Nutrition Examination Survey 2008-2011.

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    Eun Chul Kim

    Full Text Available PURPOSE: To examine the prevalence and risk factors of refractive errors in a representative Korean population aged 20 years old or older. METHODS: A total of 23,392 people aged 20+ years were selected for the Korean National Health and Nutrition Survey 2008-2011, using stratified, multistage, clustered sampling. Refractive error was measured by autorefraction without cycloplegia, and interviews were performed regarding associated risk factors including gender, age, height, education level, parent's education level, economic status, light exposure time, and current smoking history. RESULTS: Of 23,392 participants, refractive errors were examined in 22,562 persons, including 21,356 subjects with phakic eyes. The overall prevalences of myopia ( 0.5 D were 48.1% (95% confidence interval [CI], 47.4-48.8, 4.0% (CI, 3.7-4.3, and 24.2% (CI, 23.6-24.8, respectively. The prevalence of myopia sharply decreased from 78.9% (CI, 77.4-80.4 in 20-29 year olds to 16.1% (CI, 14.9-17.3 in 60-69 year olds. In multivariable logistic regression analyses restricted to subjects aged 40+ years, myopia was associated with younger age (odds ratio [OR], 0.94; 95% Confidence Interval [CI], 0.93-0.94, p < 0.001, education level of university or higher (OR, 2.31; CI, 1.97-2.71, p < 0.001, and shorter sunlight exposure time (OR, 0.84; CI, 0.76-0.93, p = 0.002. CONCLUSIONS: This study provides the first representative population-based data on refractive error for Korean adults. The prevalence of myopia in Korean adults in 40+ years (34.7% was comparable to that in other Asian countries. These results show that the younger generations in Korea are much more myopic than previous generations, and that important factors associated with this increase are increased education levels and reduced sunlight exposures.

  18. An examination of the factors controlling mercury methylation in sulfidic coastal marine sediments

    Science.gov (United States)

    Mason, R. P.; Hollweg, T. A.; Schartup, A.; Gilmour, C. C.

    2010-12-01

    The methylation of mercury (Hg) is an important step in the biogeochemical cycling and bioaccumulation of methylmercury in marine organisms. The rate of methylation is controlled by both the chemical bioavailability of Hg to methylating organisms and their activity. It is known that methylation rate decreases in sulfidic environments, especially in marine waters, but the exact mechanisms accounting for this decrease are not well-known. Modeling studies suggest that adsorption and precipitation reactions in the presence of sulfide decrease the fraction that is considered bioavailable Hg but current models predict an increase in porewater concentration at high sulfide levels, which is contrary to field observations. We have therefore focused on ascertaining why the models overestimate dissolved Hg at high sulfide levels. We have developed models that incorporate interactions between Hg, dissolved and particulate sulfide (both FeS and pyrite) and including interactions in the presence of elemental sulfur (i.e the formation of Hg-polysulfide complexes). Additionally, we are incorporating data from our studies examining the interactions between Hg and organic matter extracted from various marine ecosystems. We compare our model results, through correlation and geochemical modeling, with data from studies in the Chesapeake Bay and associated shelf and slope, and test the sensitivity of the model to the various dissolved and solid phase interactions, and the role of solid phase organic carbon and organic sulfur content in influencing the strength of partitioning. A geochemical model will be presented describing how sediment redox status influences the strength of Hg partitioning, the dissolved speciation and we will compare measured Hg methylation rate constants with our predictions of porewater bioavailable Hg concentration.

  19. An examination of the factors fueling migration amongst Community Service practitioners

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    Candice Reardon

    2014-01-01

    Full Text Available Background: Research is needed in order to understand the potential influence of the Bilateral Agreement between South Africa and the United Kingdom (UK, as well as other more recent international and local policies restricting movement of South African health workers abroad; and to determine what effect they have on the migration intentions and plans of health professionals in South Africa.Aim: The aims were to (1 explore the migration intentions and the factors that influence these intentions amongst Community Service (CS nurses and doctors; (2 explore their views and opinions about the Bilateral Agreement between the UK and South Africa (SA and other UK policies around the recruitment and employment of foreign health professionals; and (3 understand the impact of these policies on the migration plans of these CS doctors and nurses.Method: Qualitative focus groups and interviews were conducted with 23 CS doctors and nurses. To supplement this, 6 interviews were conducted with nurses and a doctor who had worked in the UK.Results: A higher disposition toward moving abroad was apparent amongst those who had experienced a challenging and frustrating CS year. Poor working conditions, including long work hours, high patient loads and inadequate resources and equipment, as well as low salaries and the perceived ambivalence of the government to the complaints of health practitioners, were influencing decisions to migrate abroad.Conclusion: The findings suggest that government efforts to better manage, recognise and respect the work and contribution of health professionals to the country would go a long way toward retaining health professionals.

  20. An examination of the factors fueling migration amongst Community Service practitioners

    Directory of Open Access Journals (Sweden)

    Candice Reardon

    2014-01-01

    Full Text Available Background: Research is needed in order to understand the potential influence of the Bilateral Agreement between South Africa and the United Kingdom (UK, as well as other more recent international and local policies restricting movement of South African health workers abroad; and to determine what effect they have on the migration intentions and plans of health professionals in South Africa.Aim: The aims were to (1 explore the migration intentions and the factors that influence these intentions amongst Community Service (CS nurses and doctors; (2 explore their views and opinions about the Bilateral Agreement between the UK and South Africa (SA and other UK policies around the recruitment and employment of foreign health professionals; and (3 understand the impact of these policies on the migration plans of these CS doctors and nurses.Method: Qualitative focus groups and interviews were conducted with 23 CS doctors and nurses. To supplement this, 6 interviews were conducted with nurses and a doctor who had worked in the UK.Results: A higher disposition toward moving abroad was apparent amongst those who had experienced a challenging and frustrating CS year. Poor working conditions, including long work hours, high patient loads and inadequate resources and equipment, as well as low salaries and the perceived ambivalence of the government to the complaints of health practitioners, were influencing decisions to migrate abroad.Conclusion: The findings suggest that government efforts to better manage, recognise and respect the work and contribution of health professionals to the country would go a long way toward retaining health professionals.

  1. Factors Influencing Student Preference When Comparing Handwriting and Typing for Essay Style Examinations

    Science.gov (United States)

    Mogey, Nora; Fluck, Andrew

    2015-01-01

    It seems anachronistic that we expect students to handwrite essay examinations when almost all their other work is mediated by computer. Two universities, one in the UK and one in Australia, are exploring the use of computers in free text response examinations. This paper compares both the attitudes and the behaviours of their students concerning…

  2. Deduction of bond length changes of symmetric molecules from experimental vibrational progressions, including a topological mass factor.

    Science.gov (United States)

    Su, Jing; Wei, Fan; Schwarz, W H E; Li, Jun

    2012-12-20

    The change ΔR(x) of bond length R(x) for atom X in a molecule upon electronic transition can be derived from the intensities I(i) of the vibrational stretching progression v = 0 → i of the electronic absorption or emission spectrum. In many cases, a simple model is sufficient for a reasonable estimate of ΔR(x). For symmetric molecules, however, conceptual problems in the literature of many decades are evident. The breathing modes of various types of symmetric molecules X(n) and AX(n) (A at the center) are here discussed. In the simplest case of a harmonic vibration of the same mode in the initial and final electronic states, we obtain ΔR(x) ≈ [2S/(ωm(x))](1/2)/w(1/2) (all quantities in atomic units). ω and S are respectively the observed vibrational quanta and the Huang-Rhys factor (corresponding, e.g., to the vibrational intensity ratio I(1)/I(0) ≈ S), m(x) is the mass of vibrating atom X, and w is a topological factor for molecule X(n) or AX(n). The factor 1/w(1/2) in the expression for ΔR(x) must not be neglected. The spectra and bond length changes of several symmetric molecules AX(n) and X(n) are discussed. The experimental bond length changes correctly derived with factor 1/w(1/2) are verified by reliable quantum chemical calculations.

  3. Catchment process affecting drinking water quality, including the significance of rainfall events, using factor analysis and event mean concentrations.

    Science.gov (United States)

    Cinque, Kathy; Jayasuriya, Niranjali

    2010-12-01

    To ensure the protection of drinking water an understanding of the catchment processes which can affect water quality is important as it enables targeted catchment management actions to be implemented. In this study factor analysis (FA) and comparing event mean concentrations (EMCs) with baseline values were techniques used to asses the relationships between water quality parameters and linking those parameters to processes within an agricultural drinking water catchment. FA found that 55% of the variance in the water quality data could be explained by the first factor, which was dominated by parameters usually associated with erosion. Inclusion of pathogenic indicators in an additional FA showed that Enterococcus and Clostridium perfringens (C. perfringens) were also related to the erosion factor. Analysis of the EMCs found that most parameters were significantly higher during periods of rainfall runoff. This study shows that the most dominant processes in an agricultural catchment are surface runoff and erosion. It also shows that it is these processes which mobilise pathogenic indicators and are therefore most likely to influence the transport of pathogens. Catchment management efforts need to focus on reducing the effect of these processes on water quality.

  4. Examining Overgeneral Autobiographical Memory as a Risk Factor for Adolescent Depression

    Science.gov (United States)

    Rawal, Adhip; Rice, Frances

    2012-01-01

    Objective: Identifying risk factors for adolescent depression is an important research aim. Overgeneral autobiographical memory (OGM) is a feature of adolescent depression and a candidate cognitive risk factor for future depression. However, no study has ascertained whether OGM predicts the onset of adolescent depressive disorder. OGM was…

  5. Examination of Factors Impacting Student Satisfaction with a New Learning Management System

    Science.gov (United States)

    Green, Lucy Santos; Inan, Fethi A.; Denton, Bree

    2012-01-01

    The purpose of this study was to determine factors that influenced student satisfaction with a new learning management system and to identify which of these factors were most important. The data was collected using an an online survey tool that was administered to students enrolled in courses designed and taught by faculty who participated in a…

  6. Science Teaching Efficacy of Preservice Elementary Teachers: Examination of the Multiple Factors Reported as Influential

    Science.gov (United States)

    Tastan Kirik, Özgecan

    2013-01-01

    This study explores the science teaching efficacy beliefs of preservice elementary teachers and the relationship between efficacy beliefs and multiple factors such as antecedent factors (participation in extracurricular activities and number of science and science teaching methods courses taken), conceptual understanding, classroom management…

  7. An Examination of the Association between Demographic and Educational Factors and African American Achievement in Science

    Science.gov (United States)

    Cottledge, Michael Christopher

    2013-01-01

    Objective of the Study: The objective of this research study was to investigate whether an association exists between teacher demographic factors (years of teaching experience and gender), 2 educational factors (certification type and certification pathway) and the percent passing rate of tenth grade African American male students on the 2010…

  8. Examining the Factor Structure of Participant Reactions to Training: A Multidimensional Approach.

    Science.gov (United States)

    Morgan, Ronald B.; Casper, Wendy J.

    2000-01-01

    Analysis of the factor structure of a large database of participant reactions to training (n=9,128) supported a multidimensional view; the utility of training was an important factor. Perceptions of the instructor carried great weight in perceptions of training. (SK)

  9. A confirmatory factor analysis of the metabolic syndrome in adolescents: an examination of sex and racial/ethnic differences

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    Gurka Matthew J

    2012-10-01

    Full Text Available Abstract Objective The metabolic syndrome (MetS is a cluster of clinical indices that signals increased risk for cardiovascular disease and Type 2 diabetes. The diagnosis of MetS is typically based on cut-off points for various components, e.g. waist circumference and blood pressure. Because current MetS criteria result in racial/ethnic discrepancies, our goal was to use confirmatory factor analysis to delineate differential contributions to MetS by sub-group. Research Design and Methods Using 1999–2010 data from the National Health and Nutrition Examination Survey (NHANES, we performed a confirmatory factor analysis of a single MetS factor that allowed differential loadings across sex and race/ethnicity, resulting in a continuous MetS risk score that is sex and race/ethnicity-specific. Results Loadings to the MetS score differed by racial/ethnic and gender subgroup with respect to triglycerides and HDL-cholesterol. ROC-curve analysis revealed high area-under-the-curve concordance with MetS by traditional criteria (0.96, and with elevations in MetS-associated risk markers, including high-sensitivity C-reactive protein (0.71, uric acid (0.75 and fasting insulin (0.82. Using a cut off for this score derived from ROC-curve analysis, the MetS risk score exhibited increased sensitivity for predicting elevations in ≥2 of these risk markers as compared with traditional pediatric MetS criteria. Conclusions The equations from this sex- and race/ethnicity-specific analysis provide a clinically-accessible and interpretable continuous measure of MetS that can be used to identify children at higher risk for developing adult diseases related to MetS, who could then be targeted for intervention. These equations also provide a powerful new outcome for use in childhood obesity and MetS research.

  10. Examining significant factors in micro and small enterprises performance: case study in Amhara region, Ethiopia

    Science.gov (United States)

    Cherkos, Tomas; Zegeye, Muluken; Tilahun, Shimelis; Avvari, Muralidhar

    2017-07-01

    Furniture manufacturing micro and small enterprises are confronted with several factors that affect their performance. Some enterprises fail to sustain, some others remain for long period of time without transforming, and most are producing similar and non-standard products. The main aim of this manuscript is on improving the performance and contribution of MSEs by analyzing impact of significant internal and external factors. Data was collected via a questionnaire, group discussion with experts and interviewing process. Randomly selected eight representative main cities of Amhara region with 120 furniture manufacturing enterprises are considered. Data analysis and presentation was made using SPSS tools (correlation, proximity, and T test) and impact-effort analysis matrix tool. The correlation analysis shows that politico-legal with infrastructure, leadership with entrepreneurship skills and finance and credit with marketing factors are those factors, which result in high correlation with Pearson correlation values of r = 0.988, 0.983, and 0.939, respectively. The study investigates that the most critical factors faced by MSEs are work premises, access to finance, infrastructure, entrepreneurship and business managerial problems. The impact of these factors is found to be high and is confirmed by the 50% drop-out rate in 2014/2015. Furthermore, more than 25% work time losses due to power interruption daily and around 65% work premises problems challenged MSEs. Further, an impact-effort matrix was developed to help the MSEs to prioritize the affecting factors.

  11. Examining evolving performance on the Force Concept Inventory using factor analysis

    Science.gov (United States)

    Semak, M. R.; Dietz, R. D.; Pearson, R. H.; Willis, C. W.

    2017-06-01

    The application of factor analysis to the Force Concept Inventory (FCI) has proven to be problematic. Some studies have suggested that factor analysis of test results serves as a helpful tool in assessing the recognition of Newtonian concepts by students. Other work has produced at best ambiguous results. For the FCI administered as a pre- and post-test, we see factor analysis as a tool by which the changes in conceptual associations made by our students may be gauged given the evolution of their response patterns. This analysis allows us to identify and track conceptual linkages, affording us insight as to how our students have matured due to instruction. We report on our analysis of 427 pre- and post-tests. The factor models for the pre- and post-tests are explored and compared along with the methodology by which these models were fit to the data. The post-test factor pattern is more aligned with an expert's interpretation of the questions' content, as it allows for a more readily identifiable relationship between factors and physical concepts. We discuss this evolution in the context of approaching the characteristics of an expert with force concepts. Also, we find that certain test items do not significantly contribute to the pre- or post-test factor models and attempt explanations as to why this is so. This may suggest that such questions may not be effective in probing the conceptual understanding of our students.

  12. Are Affective Factors a Good Predictor of Science Achievement? Examining the Role of Affective Factors Based on PISA 2006

    Science.gov (United States)

    Ozel, Murat; Caglak, Serdar; Erdogan, Mehmet

    2013-01-01

    This study investigated how affective factors like attitude and motivation contribute to science achievement in PISA 2006 using linear structural modeling. The data set of PISA 2006 collected from 4942 fifteen-year-old Turkish students (2290 females, 2652 males) was used for the statistical analyses. A total of 42 selected items on a four point…

  13. Generating induced pluripotent stem cells from common marmoset (Callithrix jacchus) fetal liver cells using defined factors, including Lin28.

    Science.gov (United States)

    Tomioka, Ikuo; Maeda, Takuji; Shimada, Hiroko; Kawai, Kenji; Okada, Yohei; Igarashi, Hiroshi; Oiwa, Ryo; Iwasaki, Tsuyoshi; Aoki, Mikio; Kimura, Toru; Shiozawa, Seiji; Shinohara, Haruka; Suemizu, Hiroshi; Sasaki, Erika; Okano, Hideyuki

    2010-09-01

    Although embryonic stem (ES) cell-like induced pluripotent stem (iPS) cells have potential therapeutic applications in humans, they are also useful for creating genetically modified human disease models in nonhuman primates. In this study, we generated common marmoset iPS cells from fetal liver cells via the retrovirus-mediated introduction of six human transcription factors: Oct-3/4, Sox2, Klf4, c-Myc, Nanog, and Lin28. Four to five weeks after introduction, several colonies resembling marmoset ES cells were observed and picked for further expansion in ES cell medium. Eight cell lines were established, and validation analyses of the marmoset iPS cells followed. We detected the expression of ES cell-specific surface markers. Reverse transcription-PCR showed that these iPS cells expressed endogenous Oct-3/4, Sox2, Klf4, c-Myc, Nanog and Lin28 genes, whereas all of the transgenes were silenced. Karyotype analysis showed that two of three iPS cell lines retained a normal karyotype after a 2-month culture. Both embryoid body and teratoma formation showed that marmoset iPS cells had the developmental potential to give rise to differentiated derivatives of all three primary germ layers. In summary, we generated marmoset iPS cells via the transduction of six transcription factors; this provides a powerful preclinical model for studies in regenerative medicine.

  14. Broadening the etiological discourse on Alzheimer's disease to include trauma and posttraumatic stress disorder as psychosocial risk factors.

    Science.gov (United States)

    Burnes, David P R; Burnette, Denise

    2013-08-01

    Biomedical perspectives have long dominated research on the etiology and progression of Alzheimer's disease (AD); yet these approaches do not solely explain observed variations in individual AD trajectories. More robust biopsychosocial models regard the course of AD as a dialectical interplay of neuropathological and psychosocial influences. Drawing on this broader conceptualization, we conducted an extensive review of empirical and theoretical literature on the associations of trauma, posttraumatic stress disorder (PTSD) and AD to develop a working model that conceptualizes the role of psychosocial stressors and physiological mechanisms in the onset and course of AD. The proposed model suggests two pathways. In the first, previous life trauma acts as a risk factor for later-life onset of AD, either directly or mediated by PTSD or PTSD correlates. In the second, de novo AD experiential trauma is associated with accelerated cognitive decline, either directly or mediated through PTSD or PTSD correlates. Evidence synthesized in this paper indicates that previous life trauma and PTSD are strong candidates as psychosocial risk factors for AD and warrant further empirical scrutiny. Psychosocial and neurological-based intervention implications are discussed. A biopsychosocial approach has the capacity to enhance understanding of individual AD trajectories, moving the field toward 'person-centered' models of care.

  15. Examination of the influence of environmental factors in contaminant vapor concentration attenuation factor with U.S. EPA’s vapor intrusion database

    Science.gov (United States)

    Yao, Yijun; Shen, Rui; Pennell, Kelly G.; Suuberg, Eric M.

    2013-01-01

    Those charged with the responsibility of estimating the risk posed by vapor intrusion (VI) processes have often looked to information contained in the U.S. Environmental Protection Agency (EPA)’s VI database for insight. Indoor air concentration attenuation factors have always been a key focus of this database, but the roles of different environmental factors in these attenuation processes are still unclear. This study aims to examine the influences of these factors in the context of the information in the VI database. The database shows that the attenuation factors vary over many orders of magnitude, and that no simple statistical fluctuation around any typical mean value exists. Thus far, no simple explanation of this phenomenon has been presented. This paper examines various possible contributing factors to the enormous range of observed values, looking at which ones can plausibly contribute to explaining them. PMID:23252837

  16. Examining the relationship of ethnicity, gender and social cognitive factors with the academic achievement of first-year engineering students

    Science.gov (United States)

    Carr, Bruce Henry

    The purpose of the study was to examine the relationships of social cognitive factors and their influence on the academic performance of first-year engineering students. The nine social cognitive variables identified were under the groupings of personal support, occupational self-efficacy, academic self-efficacy, vocational interests, coping, encouragement, discouragement, outcome expectations, and perceived stress. The primary student participants in this study were first-year engineering students from underrepresented groups which include African American, Hispanic American students and women. With this in mind, the researcher sought to examine the interactive influence of race/ethnicity and gender based on the aforementioned social cognitive factors. Differences in academic performance (university GPA of first-year undergraduate engineering students) were analyzed by ethnicity and gender. There was a main effect for ethnicity only. Gender was found not to be significant. Hispanics were not found to be significantly different in their GPAs than Whites but Blacks were found to have lower GPAs than Whites. Also, Pearson correlation coefficients were used to examine the relationship between and among the nine identified social cognitive variables. The data from the analysis uncovered ten significant correlations which were as follows: occupational self-efficacy and academic self-efficacy, occupational self-efficacy and vocational interest, occupational self-efficacy and perceived stress, academic self-efficacy and encouragement, academic self-efficacy and outcome expectations, academic self-efficacy and perceived stress, vocational interest and outcome expectations, discouragement and encouragement, coping and perceived stress, outcome expectations and perceived stress. Next, a Pearson correlation coefficient was utilized to examine the relationship between academic performance (college GPA) of first-year undergraduate engineering students and the nine identified

  17. [Factor analysis of the structure of nocturnal sleep and the results of psychodiagnostic examination in man].

    Science.gov (United States)

    Nikiforuk, K K; Rotenberg, V S; Rashidov, N R; Laneev, A I

    1986-01-01

    Factor analysis was carried out of sleep structure and results of complex psychodiagnostic study in 35 subjects. Seven orthogonal factors were singled out. It is shown that alarm level is connected with fast sleep general presentation; the system of psychological defences is linked with the fast sleep in the second cycle; the self-control in alert state and the transfer from alertness to sleep are interrelated, and duration of the first and last sleep cycles are reciprocally connected.

  18. Examination of factors that affect the composition and function of the microbiota

    OpenAIRE

    Berg, Maureen

    2017-01-01

    The microbiota is an important contributor to host health and fitness, impacting all aspects of life, from development and metabolism to immunity and behavior. Substantial work has been done to characterize the factors that shape the microbiota, and have demonstrated the importance of both environmental and host factors. However, much of the multifaceted relationship between the environment, the host, and the microbiota remains to be elucidated. My dissertation attempts to demonstrate the way...

  19. Thinking Structurally About Narcissism: An Examination of the Five-Factor Narcissism Inventory and Its Components.

    Science.gov (United States)

    Miller, Joshua D; Lynam, Donald R; McCain, Jessica L; Few, Lauren R; Crego, Cristina; Widiger, Thomas A; Campbell, W Keith

    2016-02-01

    The Five-Factor Narcissism Inventory (FFNI) is a self-report measure of the traits linked to grandiose and vulnerable narcissism, as well as narcissistic personality disorder (NPD), from a five-factor model perspective (FFM). In the current studies, the factor structure of the FFNI was explored and the results supported the extraction of three factors: Antagonism (e.g., Arrogance), Neuroticism (e.g., Need for Admiration), and Agentic Extraversion (e.g., Authoritativeness). In Study 2, the FFNI factors manifested convergent validity with their corresponding Big Five domains and diverging relations with measures of grandiose and vulnerable narcissism, NPD, and self-esteem. Ultimately, the FFNI factors help explicate the differences between various expressions of narcissism such that all are related to Antagonism but differ with regard to Neuroticism (relevant to vulnerable narcissism and NPD) and Agentic Extraversion (relevant to grandiose narcissism and NPD). The results also highlight the complex relation between self-esteem and the traits that comprise narcissism measures.

  20. Factor structure of the Eating Disorder Examination Questionnaire (EDE-Q) in male and female college athletes.

    Science.gov (United States)

    Darcy, Alison M; Hardy, Kristina K; Crosby, Ross D; Lock, James; Peebles, Rebecka

    2013-06-01

    The study explored the psychometric properties of the Eating Disorder Examination Questionnaire (EDE-Q) among 1637 university students. Participants were divided into male (n=432) and female (n=544) competitive athletes, and male (n=229) and female (n=429) comparison groups comprised of individuals who had not engaged in competitive sports for at least one year. All groups were subjected to confirmatory factor analysis (CFA) to test the fit of the published factor structure in this population, and then exploratory FA (EFA). A three-factor solution was the best fit for three out of four groups, with a two-factor solution providing best fit for the male comparison group. The first factor for all groups resembled a combined Shape and Weight Concern subscale. The factor structure among male and female competitive athletes was remarkably similar; however, non-competitive athletic/low activity males appear qualitatively different from other groups.

  1. Complex analysis of Askaryan radiation: A fully analytic treatment including the LPM effect and Cascade Form Factor

    Science.gov (United States)

    Hanson, Jordan C.; Connolly, Amy L.

    2017-05-01

    The Askaryan effect describes coherent electromagnetic radiation from high-energy cascades in dense media with a collective charge. We present an analytic model of Askaryan radiation that accounts simultaneously for the three-dimensional form factor of the cascade, and quantum mechanical cascade elongation via the Landau-Pomeranchuk-Migdal effect. These calculations, and the associated open-source code, allow the user to avoid computationally intensive Monte Carlo cascade simulations. Searches for cosmogenic neutrinos in Askaryan-based detectors benefit from computational speed, because scans of Askaryan parameter-space are required to match neutrino signals. The Askaryan field is derived from cascade equations verified with Geant4 simulations, and compared with prior numerical and semi-analytic calculations. Finally, instructive cases of the model are transformed from the Fourier domain to the time-domain. Next-generation in situ detectors like ARA and ARIANNA can use analytic time-domain signal models to search for correlations with event candidates.

  2. Complex Analysis of Askaryan Radiation: A Fully Analytic Treatment including the LPM effect and Cascade Form Factor

    CERN Document Server

    Hanson, Jordan C

    2016-01-01

    The Askaryan effect describes coherent electromagnetic radiation from the collective charge within high-energy cascades in dense media. We present the first fully analytic model of Askaryan radiation that accounts simultaneously for the three-dimensional form factor of the electromagnetic cascade and the Landau-Pomeranchuk-Migdal (LPM) effect. Analytic calculations avoid computationally intensive Monte Carlo simulations of the cascades. Searches for cosmogenic neutrinos in Askaryan- based detectors benefit from computational speed, because neutrino event parameters affect the shape of the electromagnetic field, requiring scans of parameter space. The Askaryan field is derived and verified against Geant4 simulations, and compared with prior numerical and semi-analytic calculations. Finally, two special cases of the model are transformed from the Fourier domain to the time-domain, analytically. Next-generation in situ detectors like ARA and ARIANNA can use analytic time-domain signal models to search for phase ...

  3. Awareness of breast cancer risk factors and practice of breast self examination among high school students in Turkey

    OpenAIRE

    Çetinkaya Aynur; Özmen Dilek; Karayurt Özgül

    2008-01-01

    Abstract Background Young breast cancer patients have a lower rate of survival than old breast cancer patients due to being diagnosed at advanced stages. Breast self-examination makes women more "breast aware", which in turn may lead to an earlier diagnosis of breast cancer. The purpose of this study was to investigate knowledge and practice of breast self-examination and to determine knowledge of risk factors for breast cancer among high school students. Methods This is a descriptive and cro...

  4. An examination of the factor structure of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, narcissistic personality disorder criteria: one or two factors?

    Science.gov (United States)

    Miller, Joshua D; Hoffman, Brian J; Campbell, W Keith; Pilkonis, Paul A

    2008-01-01

    A growing body of research has suggested that narcissistic personality disorder (NPD) contains 2 factors or types: overt/grandiose and covert/vulnerable. A recent factor analysis of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), NPD symptoms supported a similar 2-factor model. The present research tested this proposed 2-factor solution against a 1-factor solution (N = 289; 72% patients) using both confirmatory factor analysis and an examination of associations between the resultant factors and theoretically relevant criteria (other personality disorders; depression, anxiety). The results of the confirmatory factor analysis supported a 1-factor solution. Likewise, the 2 factors each yielded a similar pattern of correlations with relevant criteria. Together, these results argue against a 2-factor structure for the current DSM-IV NPD symptoms. Given the broader research literature suggesting a 2-factor structure of narcissism, strategies for assessing both overt/grandiose and covert/vulnerable forms of narcissism in DSM-V are discussed.

  5. Examining Factor Structure of the Chinese Version of the PIRLS 2011 Home Questionnaire

    Directory of Open Access Journals (Sweden)

    Wai Ming Cheung

    2016-01-01

    Full Text Available The home questionnaire of the Progress in International Reading Literacy Study (PIRLS-HQ 2011 was designed to gather information from parents or primary caregivers of fourth-grade pupils on their reading literacy development related to aspects of pupils’ home lives across countries/districts. The questionnaire was translated into different languages for international comparison and research purposes. This study aims to assess the psychometric properties of the Chinese version of the PIRLS 2011 home questionnaire (PIRLS-HQCV 2011 and identify the underlying factor structure using exploratory factor analysis (EFA and confirmatory factor analysis (CFA among Chinese fourth-grade pupils in Hong Kong. A 7-factor structure model has been identified by EFA and confirmed to resemble much to the original PIRLS structure by CFA. Additional conceptually important domains have been identified which add further insights into the inconclusive results in the literature regarding the relationship between home factors and reading achievement. Implications for further studies are discussed.

  6. Examining the impact of worker and workplace factors on prolonged work absences among Canadian nurses.

    Science.gov (United States)

    Franche, Renée-Louise; Murray, Eleanor; Ibrahim, Selahadin; Smith, Peter; Carnide, Nancy; Côté, Pierre; Gibson, Jane; Koehoorn, Mieke

    2011-08-01

    To evaluate the impact of worker and workplace factors and of their relationships on work absence duration. Structural equation modeling of 11,762 female, Canadian nurses from the 2005 National Survey of the Work and Health of Nurses. Worker and workplace factors were associated with prolonged work absence. Key proximal predictors were pain-related work interference, depression, pain severity, and respect and support at work. More distal predictors were multimorbidity, abuse at work, and organizational culture. Worker health and workplace factors are important in explaining work absence duration. Self-management for pain and mood, adapted to the work context, may be useful for nurses with chronic pain or depression. Policy makers and administrators should focus on creating respect and support at work, and improving organizational culture.

  7. Confirmatory Factor Analysis of the Structure of Statistics Anxiety Measure: An Examination of Four Alternative Models

    Directory of Open Access Journals (Sweden)

    Hossein Bevrani, PhD

    2011-09-01

    Full Text Available Objective: The aim of this study is to explore the confirmatory factor analysis results of the Persian adaptation of Statistics Anxiety Measure (SAM, proposed by Earp.Method: The validity and reliability assessments of the scale were performed on 298 college students chosen randomly from Tabriz University in Iran. Confirmatory factor analysis (CFA was carried out to determine the factor structures of the Persian adaptation of SAM.Results: As expected, the second order model provided a better fit to the data than the three alternative models. Conclusions: Hence, SAM provides an equally valid measure for use among college students. The study both expands and adds support to the existing body of math anxiety literature.

  8. Examining Marketing Officers' Demographic Factors' Influence on MIHE Scores at California Community Colleges

    Science.gov (United States)

    Hall, Zachary Martin

    2012-01-01

    Research indicates that one way to investigate a college's dedication to marketing is to examine the role, influence, and support the marketing officer receives on their campus. Based on the literature's premise that marketing officers are a measure of commitment, this study explored the relationship between Marketing Index of Higher Education…

  9. Success of Developmental Readers: An Examination of Factors Affecting Attrition and Institutional Practices Which Support Retention

    Science.gov (United States)

    O'Brien, Katherine F.

    2013-01-01

    Students who enter higher education requiring reading remediation have poor institutional persistence. This study examined the course success and first-year institutional persistence of six women enrolled in a developmental reading course at a regional campus of a state university. Data sets were comprised of classroom observation, review of…

  10. Examining Marketing Officers' Demographic Factors' Influence on MIHE Scores at California Community Colleges

    Science.gov (United States)

    Hall, Zachary Martin

    2012-01-01

    Research indicates that one way to investigate a college's dedication to marketing is to examine the role, influence, and support the marketing officer receives on their campus. Based on the literature's premise that marketing officers are a measure of commitment, this study explored the relationship between Marketing Index of Higher Education…

  11. Factors Associated with Success in a Calculus Course: An Examination of Personal Variables

    Science.gov (United States)

    Ubuz, Behiye

    2011-01-01

    This study examined relationships between students' personal variables (gender, prior achievements, age and academic major) and their success in the first year undergraduate calculus course. The study sample consisted of 59 first year undergraduate students taking Math 154 Calculus II course. A written test about integral, sequence and series…

  12. Student Motivation in Graduate Music Programmes: An Examination of Personal and Environmental Factors

    Science.gov (United States)

    Gonzalez-Moreno, Patricia Adelaida

    2012-01-01

    Despite the increasing number of students in music education graduate programmes, attrition rates suggest a lack of success in retaining and assisting them to the completion of their degree. Based on the expectancy-value theory, the aim of this study was to examine students' motivations (values and competence beliefs) and their complex interaction…

  13. The Fear Factor: Students' Experiences of Test Anxiety when Taking A-Level Examinations

    Science.gov (United States)

    Chamberlain, Suzanne; Daly, Anthony Leslie; Spalding, Victoria

    2011-01-01

    This paper presents the findings of a pilot study that explored students' experiences of test anxiety when taking A-level examinations. Four focus groups were convened with a sample of 19 participants in the south of England to explore the triggers of test anxiety and the perceived need for interventions to assist high test-anxious students cope…

  14. Achieving the Dream: An Examination of Success Factors with a Focus on Cultural Changes

    Science.gov (United States)

    Cornelius, Cathy D.

    2013-01-01

    This study examines the change process to enhance student persistence and graduation rates in four North Carolina community colleges. Using a qualitative research methodology, Lewin's change model is presented as a framework to investigate the acceptance and implementation of AtD principles in two community colleges. Processes to enhance student…

  15. Success of Developmental Readers: An Examination of Factors Affecting Attrition and Institutional Practices Which Support Retention

    Science.gov (United States)

    O'Brien, Katherine F.

    2013-01-01

    Students who enter higher education requiring reading remediation have poor institutional persistence. This study examined the course success and first-year institutional persistence of six women enrolled in a developmental reading course at a regional campus of a state university. Data sets were comprised of classroom observation, review of…

  16. Immigrants Outperform Canadian-Born Groups in French Immersion: Examining Factors That Influence Their Achievement

    Science.gov (United States)

    Mady, Callie

    2015-01-01

    This paper examines the French achievement results of three groups of students: Canadian-born English/French bilingual, Canadian-born multilingual and immigrant multilingual Grade 6 French immersion students, by investigating how the variables of integrative and instrumental motivations, attitudes to the learning situation, French language…

  17. Immigrants Outperform Canadian-Born Groups in French Immersion: Examining Factors That Influence Their Achievement

    Science.gov (United States)

    Mady, Callie

    2015-01-01

    This paper examines the French achievement results of three groups of students: Canadian-born English/French bilingual, Canadian-born multilingual and immigrant multilingual Grade 6 French immersion students, by investigating how the variables of integrative and instrumental motivations, attitudes to the learning situation, French language…

  18. Examining Contextual Factors in the Career Decision Status of African American Adolescents

    Science.gov (United States)

    Constantine, Madonna G.; Wallace, Barbara C.; Kindaichi, Mai M.

    2005-01-01

    This study examined the extent to which perceived occupational barriers and perceived parental support predicted career certainty and career indecision in a sample of African American adolescents. Perceived occupational barriers were positively predictive of career indecision, and perceived parental support was positively associated with career…

  19. Further Examination of Factors that Influence Preference for Positive versus Negative Reinforcement

    Science.gov (United States)

    Kodak, Tiffany; Lerman, Dorothea C.; Volkert, Valerie M.; Trosclair, Nicole

    2007-01-01

    Factors that influence choice between qualitatively different reinforcers (e.g., a food item or a break from work) are important to consider when arranging treatments for problem behavior. Previous findings indicate that children who engage in problem behavior maintained by escape from demands may choose a food item over the functional reinforcer…

  20. Examining the Relationship between Technological, Organizational, and Environmental Factors and Cloud Computing Adoption

    Science.gov (United States)

    Tweel, Abdeneaser

    2012-01-01

    High uncertainties related to cloud computing adoption may hinder IT managers from making solid decisions about adopting cloud computing. The problem addressed in this study was the lack of understanding of the relationship between factors related to the adoption of cloud computing and IT managers' interest in adopting this technology. In…

  1. A Human Factors Analysis and Classification System (HFACS) Examination of Commercial Vessel Accidents

    Science.gov (United States)

    2012-09-01

    experienced workers, such as in an apprenticeship . The amount of conscious decision- making or cognitive thinking is higher than in rule-based...human-machine interaction : an approach to cognitive engineering . North-Holland: Elsevier Science. Rasmussen, J. (1983). Skills, rules, and... Engineering HFWG Human Factors Working Group HSI Human Systems Integration IMO International Maritime Organization IIC Investigator-in-Charge

  2. Examining the unique relations between anxiety sensitivity factors and suicidal ideation and past suicide attempts.

    Science.gov (United States)

    Allan, Nicholas P; Norr, Aaron M; Boffa, Jay W; Durmaz, Daphne; Raines, Amanda M; Schmidt, Norman B

    2015-08-30

    Anxiety sensitivity (AS) has recently been linked to suicidality. Specifically, AS cognitive concerns has been implicated as a risk factor, and AS physical concerns as a protective factor, for suicidal ideation and suicide attempts. However, no studies have used structural equation modeling (SEM) to address issues of skewed suicide variables and bifactor modeling of AS to address the high degree of overlap between the lower-order dimensions of AS that limit interpretation of these past findings. AS, suicidal ideation, past suicide attempts, and depression were assessed in a clinical sample of 267 individuals (M age=35.45 years, SD=16.53; 52.1% female). The global AS and AS cognitive concerns factors were positively, significantly associated with suicidal ideation, though these effects were nonsignificant controlling for depression. The global AS factor was positively, significantly associated with suicide attempts, controlling for depression. The current study demonstrated that the relations between AS and suicidal ideation are not maintained when accounting for depression, suggesting that the relation between AS and suicidal ideation may be mediated by depression. The positive relation between global AS and suicide attempts is consistent with theories positing suicide attempts as a consequence of an inability to cope with intolerable distress.

  3. Examining Factors That Influence Donor Motivation among Former Student-Athletes and NCAA DI Classification

    Science.gov (United States)

    Burchette, Brett M.

    2013-01-01

    The purpose of this study was to identify motivational factors that contribute to the philanthropic decision making of the former NCAA Division I student-athlete. A 47-item survey instrument was modified from a prior study and distributed electronically to 8,461 male and female former student-athletes at three participating NCAA Division I…

  4. Examining Factors That Influence Donor Motivation among Former Student-Athletes and NCAA DI Classification

    Science.gov (United States)

    Burchette, Brett M.

    2013-01-01

    The purpose of this study was to identify motivational factors that contribute to the philanthropic decision making of the former NCAA Division I student-athlete. A 47-item survey instrument was modified from a prior study and distributed electronically to 8,461 male and female former student-athletes at three participating NCAA Division I…

  5. Examining the Relationship between Technological, Organizational, and Environmental Factors and Cloud Computing Adoption

    Science.gov (United States)

    Tweel, Abdeneaser

    2012-01-01

    High uncertainties related to cloud computing adoption may hinder IT managers from making solid decisions about adopting cloud computing. The problem addressed in this study was the lack of understanding of the relationship between factors related to the adoption of cloud computing and IT managers' interest in adopting this technology. In…

  6. Free for All: A Case Study Examining Implementation Factors of One-to-One Device Programs

    Science.gov (United States)

    Howard, Sarah K.; Rennie, Ellie

    2013-01-01

    Despite significant investment in school one-to-one device programs, little is known about which aspects of program implementation work and why. Through a comparison of two implementation models, adopter-diffusion and saturation, and using existing data from the One Laptop per Child Australia laptop program, we explored how factors of…

  7. An Examination of Factors Associated with School Psychologists' Provision of Counseling Services

    Science.gov (United States)

    DeFago, Jennifer Kelly

    2012-01-01

    The purpose of this study was to evaluate the factors that predict provision of counseling services by Ohio-based school psychologists. In order to address the research questions, a survey instrument was created and a sample of school psychologists working in Ohio completed a questionnaire regarding their counseling practices. The data were…

  8. Examining the Factors That Contribute to Successful Database Application Implementation Using the Technology Acceptance Model

    Science.gov (United States)

    Nworji, Alexander O.

    2013-01-01

    Most organizations spend millions of dollars due to the impact of improperly implemented database application systems as evidenced by poor data quality problems. The purpose of this quantitative study was to use, and extend, the technology acceptance model (TAM) to assess the impact of information quality and technical quality factors on database…

  9. Using Epidemiological Survey Data to Examine Factors Influencing Participation in Parent-Training Programmes

    Science.gov (United States)

    Morawska, Alina; Dyah Ramadewi, Mikha; Sanders, Matthew R.

    2014-01-01

    Evidence-based parent-training programmes aim to reduce child behaviour problems; however, the effects of these programmes are often limited by poor participation rates. This study proposes a model of parent, child and family factors related to parental participation in parenting interventions. A computer-assisted telephone interview was used to…

  10. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer

    LENUS (Irish Health Repository)

    Cathcart, Mary-Clare

    2011-03-09

    Abstract Background Thromboxane synthase (TXS) metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibition induces cell death in-vitro, providing a rationale for therapeutic intervention. We aimed to determine the expression profile of TXS in NSCLC and if it is prognostic and\\/or a survival factor in the disease. Methods TXS expression was examined in human NSCLC and matched controls by western analysis and IHC. TXS metabolite (TXB2) levels were measured by EIA. A 204-patient NSCLC TMA was stained for COX-2 and downstream TXS expression. TXS tissue expression was correlated with clinical parameters, including overall survival. Cell proliferation\\/survival and invasion was examined in NSCLC cells following both selective TXS inhibition and stable TXS over-expression. Results TXS was over-expressed in human NSCLC samples, relative to matched normal controls. TXS and TXB2 levels were increased in protein (p < 0.05) and plasma (p < 0.01) NSCLC samples respectively. TXS tissue expression was higher in adenocarcinoma (p < 0.001) and female patients (p < 0.05). No significant correlation with patient survival was observed. Selective TXS inhibition significantly reduced tumour cell growth and increased apoptosis, while TXS over-expression stimulated cell proliferation and invasiveness, and was protective against apoptosis. Conclusion TXS is over-expressed in NSCLC, particularly in the adenocarcinoma subtype. Inhibition of this enzyme inhibits proliferation and induces apoptosis. Targeting thromboxane synthase alone, or in combination with conventional chemotherapy is a potential therapeutic strategy for NSCLC.

  11. The complexity of vesicle transport factors in plants examined by orthology search.

    Directory of Open Access Journals (Sweden)

    Puneet Paul

    Full Text Available Vesicle transport is a central process to ensure protein and lipid distribution in eukaryotic cells. The current knowledge on the molecular components and mechanisms of this process is majorly based on studies in Saccharomyces cerevisiae and Arabidopsis thaliana, which revealed 240 different proteinaceous factors either experimentally proven or predicted to be involved in vesicle transport. In here, we performed an orthologue search using two different algorithms to identify the components of the secretory pathway in yeast and 14 plant genomes by using the 'core-set' of 240 factors as bait. We identified 4021 orthologues and (co-orthologues in the discussed plant species accounting for components of COP-II, COP-I, Clathrin Coated Vesicles, Retromers and ESCRTs, Rab GTPases, Tethering factors and SNAREs. In plants, we observed a significantly higher number of (co-orthologues than yeast, while only 8 tethering factors from yeast seem to be absent in the analyzed plant genomes. To link the identified (co-orthologues to vesicle transport, the domain architecture of the proteins from yeast, genetic model plant A. thaliana and agriculturally relevant crop Solanum lycopersicum has been inspected. For the orthologous groups containing (co-orthologues from yeast, A. thaliana and S. lycopersicum, we observed the same domain architecture for 79% (416/527 of the (co-orthologues, which documents a very high conservation of this process. Further, publically available tissue-specific expression profiles for a subset of (co-orthologues found in A. thaliana and S. lycopersicum suggest that some (co-orthologues are involved in tissue-specific functions. Inspection of localization of the (co-orthologues based on available proteome data or localization predictions lead to the assignment of plastid- as well as mitochondrial localized (co-orthologues of vesicle transport factors and the relevance of this is discussed.

  12. Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate cardiometabolic risk factors.

    Science.gov (United States)

    Babish, John G; Dahlberg, Clinton J; Ou, Joseph J; Keller, William J; Gao, Wei; Kaadige, Mohan R; Brabazon, Holly; Lamb, Joseph; Soudah, Hani C; Kou, Xiaolan; Zhang, Zhe; Pacioretty, Linda M; Tripp, Matthew L

    2016-12-01

    We examined the clinical safety and efficacy of F105 in 11 subjects with moderate dyslipidemia. F105 is a combination of bergamot fruit extract (Citrus bergamia, BFE) and 9 phytoextracts selected for their ability to improve the antioxidant and anti-inflammatory activity of BFE. In vitro F105 exhibited a synergistic inhibition of oxygen radical absorbing capacity, peroxynitrite formation, and myeloperoxidase activity. Following 12 weeks of F105 daily, no treatment-related adverse events or changes in body mass were seen. Statistically significant changes were noted in total cholesterol (-7.3%), LDL-cholesterol (-10%), non-HDL cholesterol (-7.1%), cholesterol/HDL (-26%), and apolipoprotein B (-2.8%). A post hoc analysis of 8 subjects with HbA1c > 5.4 and HOMA-IR score > 2 or elevated triglycerides revealed additional statistically significant changes in addition to those previously observed in all subjects including triglycerides (-27%), oxLDL (-19%), LDL/HDL (-25%), triglycerides/HDL (-27%), oxLDL/HDL (-25%), and PAI-1 (-37%). A follow-up case report of a 70-year-old female patient, nonresponsive to statin therapy and placed on F105 daily, demonstrated improved cardiometabolic variables over 12 weeks similar to the subgroup. In summary, F105 was clinically well-tolerated and effective for ameliorating dyslipidemia in subjects with moderate cardiometabolic risk factors, particularly in the individuals with HbA1c > 5.4%.

  13. Contrast examination as a prognostic factor in the treatment of solitary bone cyst by cortisone injection

    Energy Technology Data Exchange (ETDEWEB)

    Capanna, R.; Campanacci, M.; Albisinni, U.; Caroli, G.C.

    1984-07-01

    Local injection of radiopaque medium demonstrated the presence of intracystic fibrous septa in 13 patients with solitary bone cyst. Contrast examination was helpful in predicting the response of solitary bone cysts to treatment by injection of methylprednisolone-acetate (MPA). As the number of septa increased, an increased difficulty in obtaining an equal distribution of MPA inside the cyst and a higher incidence of incomplete healing of the cyst was encountered.

  14. Alcoholism, associated risk factors, and harsh parenting among fathers: Examining the role of marital aggression

    OpenAIRE

    Finger, Brent; Kachadourian, Lorig K.; Molnar, Danielle S.; Eiden, Rina D.; Edwards, Ellen P.; Leonard, Kenneth E.

    2010-01-01

    This study utilized a longitudinal design to examine relations between paternal alcoholism, paternal psychopathology, marital aggression and fathers’ harsh parenting behavior in a sample of children with alcoholic (n=89) and non-alcoholic (n=94) fathers. Structural Equation Modeling revealed that paternal alcoholism, depression, and antisocial behavior at 12 months of child age each predicted higher levels of marital aggression at 36 months. Moreover, after controlling for prior parenting, ma...

  15. Examining the relationship between service quality and customer satisfaction: a factor specific approach

    OpenAIRE

    Azman Ismail; Ahmad Azan Ridzuan; Nur Ilyani Ranlan Rose; Muhammad Madi Bin Abdullah; Muhammad Sabbir Rahman; Sebastian K. Francis

    2013-01-01

    Purpose: This research was aimed at examining the relationship between service quality and customer satisfaction with data obtained from Malaysian soldiers who were involved in peace keeping missions in a Middle Eastern country. The results of which would enable the management to improve the quality of service accorded to peacekeeping personnel. Design/methodology/approach: The study employed a cross-sectional research design which allowed the researchers to integrate the service quality lite...

  16. Effect of yoga practices on pulmonary function tests including transfer factor of lung for carbon monoxide (TLCO) in asthma patients.

    Science.gov (United States)

    Singh, Savita; Soni, Ritu; Singh, K P; Tandon, O P

    2012-01-01

    Prana is the energy, when the self-energizing force embraces the body with extension and expansion and control, it is pranayama. It may affect the milieu at the bronchioles and the alveoli particularly at the alveolo-capillary membrane to facilitate diffusion and transport of gases. It may also increase oxygenation at tissue level. Aim of our study is to compare pulmonary functions and diffusion capacity in patients of bronchial asthma before and after yogic intervention of 2 months. Sixty stable asthmatic-patients were randomized into two groups i.e group 1 (Yoga training group) and group 2 (control group). Each group included thirty patients. Lung functions were recorded on all patients at baseline, and then after two months. Group 1 subjects showed a statistically significant improvement (Pyoga practice. Quality of life also increased significantly. It was concluded that pranayama & yoga breathing and stretching postures are used to increase respiratory stamina, relax the chest muscles, expand the lungs, raise energy levels, and calm the body.

  17. Examining the relationship between service quality and customer satisfaction: A factor specific approach

    Directory of Open Access Journals (Sweden)

    Azman Ismail

    2013-06-01

    Full Text Available Purpose: This research was aimed at examining the relationship between service quality and customer satisfaction with data obtained from Malaysian soldiers who were involved in peace keeping missions in a Middle Eastern country. The results of which would enable the management to improve the quality of service accorded to peacekeeping personnel. Design/methodology/approach: The study employed a cross-sectional research design which allowed the researchers to integrate the service quality literature, the semi structured interview and the actual survey to collect and examine the data for optimum results. Findings and Originality/value: The outcome of multiple regression analysis showed that responsiveness and assurance variables reflected a high correlation with customer satisfaction. On the other hand, tangibility, reliability and empathy variables recorded an insignificant correlation with customer satisfaction. Research limitations/implications: With respect to practical contributions, the findings of this study can be used as a guideline by the management to improve the quality of peacekeeping in areas of conflict. Practical implications: For security reasons, certain information affecting customer satisfaction could not be examined in detail. Originality/value: This paper presents key results on service quality and customers satisfaction research by looking at the niche segment which was not previously studied from the Malaysian perspective.

  18. A causal examination of the effects of confounding factors on multimetric indices

    Science.gov (United States)

    Schoolmaster, Donald R.; Grace, James B.; Schweiger, E. William; Mitchell, Brian R.; Guntenspergen, Glenn R.

    2013-01-01

    The development of multimetric indices (MMIs) as a means of providing integrative measures of ecosystem condition is becoming widespread. An increasingly recognized problem for the interpretability of MMIs is controlling for the potentially confounding influences of environmental covariates. Most common approaches to handling covariates are based on simple notions of statistical control, leaving the causal implications of covariates and their adjustment unstated. In this paper, we use graphical models to examine some of the potential impacts of environmental covariates on the observed signals between human disturbance and potential response metrics. Using simulations based on various causal networks, we show how environmental covariates can both obscure and exaggerate the effects of human disturbance on individual metrics. We then examine from a causal interpretation standpoint the common practice of adjusting ecological metrics for environmental influences using only the set of sites deemed to be in reference condition. We present and examine the performance of an alternative approach to metric adjustment that uses the whole set of sites and models both environmental and human disturbance effects simultaneously. The findings from our analyses indicate that failing to model and adjust metrics can result in a systematic bias towards those metrics in which environmental covariates function to artificially strengthen the metric–disturbance relationship resulting in MMIs that do not accurately measure impacts of human disturbance. We also find that a “whole-set modeling approach” requires fewer assumptions and is more efficient with the given information than the more commonly applied “reference-set” approach.

  19. Examining Factors Associated with (In)Stability in Social Information Processing among Urban School Children: A Latent Transition Analytic Approach

    Science.gov (United States)

    Goldweber, Asha; Bradshaw, Catherine P.; Goodman, Kimberly; Monahan, Kathryn; Cooley-Strickland, Michele

    2011-01-01

    There is compelling evidence for the role of social information processing (SIP) in aggressive behavior. However, less is known about factors that influence stability versus instability in patterns of SIP over time. Latent transition analysis was used to identify SIP patterns over one year and examine how community violence exposure, aggressive…

  20. Analysis of risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly undergoing health examination

    Institute of Scientific and Technical Information of China (English)

    王蕾蕾

    2013-01-01

    Objective To investigate the prevalences of benign prostatic hyperplasia (BPH) and metabolic syndrome (MS) and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods A total of 490 elderly men undergoing health examination in our hospital from January 2010 to

  1. Toward Digital Citizenship: Examining Factors Affecting Participation and Involvement in the Internet Society among Higher Education Students

    Science.gov (United States)

    Al-Zahrani, Abdulrahman

    2015-01-01

    The current study aims to understand digital citizenship, based on the assumptions of Ribble (2014), by examining factors affecting participation and involvement in the Internet virtual societies among higher education students. A quantitative approach using a survey questionnaire was implemented. The participants were 174 students from the…

  2. Examining the lived experience and factors influencing education of two student veterans using photovoice methodology.

    Science.gov (United States)

    Tomar, Nikhil; Stoffel, Virginia

    2014-01-01

    OBJECTIVE. We sought to understand the lived experience of 2 student veterans and identify factors influencing their higher education. METHOD. A qualitative research design was used with 2 student veterans who engaged in photovoice methodology. We analyzed their photographs, accompanying narratives, and discussion session transcripts using descriptive coding and thematic analysis. RESULTS. Data analysis revealed four themes: (1) reminiscence of past duty and reflections on military life, (2) transition from military life to civilian student life, (3) entry to a new stage of life, and (4) influence of the university and community environment. CONCLUSION. Findings from this study revealed factors influencing student veterans' education and can be used to develop occupation-based interventions to assist veterans who engage in higher education. Copyright © 2014 by the American Occupational Therapy Association, Inc.

  3. A factor analytic and psychometric examination of pathology of separation-individuation.

    Science.gov (United States)

    Lapsley, D K; Aalsma, M C; Varshney, N M

    2001-07-01

    Two studies are described that attempt to determine if standard-scale-reduction techniques could yield a construct-valid diagnostic screen of pathology of separation-individuation for use in nonclinical university settings. In Study 1 (N = 210), a measure of pathology of separation-individuation (PATHSEP) was reduced successfully to a single, internally consistent factor, accounting for 36% of the variance. In Study 2 (N = 304), these items also coalesced around a single factor, accounting for 35% of the variance. Study 2 also showed that PATHSEP is correlated moderately and positively with indices of insecure attachment, with the Center for Epidemiological Studies-Depression Scale, and with indices of psychiatric symptomatology (Hopkins Symptom Checklist). PATHSEP also was associated with a poorer profile of adjustment to college. Males reported more pathology of separation-individuation than did females. Evidence supports the construct validity of a shortened version of PATHSEP. Directions for future research are noted. Copyright 2001 John Wiley & Sons, Inc.

  4. Examination of lifestyle factors and diseases in teaching periodontology in dental education in the Nordic countries

    DEFF Research Database (Denmark)

    Fiehn, Nils-Erik; Christensen, Lisa Bøge

    2016-01-01

    INTRODUCTION: Lifestyle and general diseases are important for the development of periodontitis and other diseases in the oral cavity. Therefore, knowledge on lifestyle factors must be part of the dental curriculum. However, a search for information in the literature databases gave meagre results....... The aim of this study was to describe education of lifestyle in relation to diseases in the oral cavity with focus on periodontitis and to elucidate how education is practiced and reflected in dental education in the Nordic countries. MATERIALS AND METHODS: A questionnaire, which consisted of 18 questions...... in the content across the dental schools, there were also similarities. So, at all schools smoking, medication, cardiovascular diseases and diabetes type 2 had a high priority. Education of other factors such as alcohol, psychological stress, oral hygiene habits, hypotension and obesity varied. CONCLUSION...

  5. An Examination of the Factors Associated with the ‘Crime Drop’ in England and Wales

    OpenAIRE

    Ignatans, Dainis

    2015-01-01

    The explanations of the remarkable decrease in crime that has been reported over the last two decades in a number of western countries thus far are assessed here as having been limited and unconvincing. In the light of these limitations, this thesis explores three under researched factors and their potential impact on recorded and reported crime rates in England and Wales. First, the contribution of security measures to the fall in crime is evaluated. The likely impact of security measures is...

  6. Further Examination of Factors that Influence Preference for Positive Versus Negative Reinforcement

    OpenAIRE

    Kodak, Tiffany; Lerman, Dorothea C; Volkert, Valerie M.; Trosclair, Nicole

    2007-01-01

    Factors that influence choice between qualitatively different reinforcers (e.g., a food item or a break from work) are important to consider when arranging treatments for problem behavior. Previous findings indicate that children who engage in problem behavior maintained by escape from demands may choose a food item over the functional reinforcer during treatment (DeLeon, Neidert, Anders, & Rodriguez-Catter, 2001; Lalli et al., 1999). However, a number of variables may influence choice betwee...

  7. A prospective examination of risk factors in the development of intrusions following a trauma analog.

    Science.gov (United States)

    Ripley, Adam J; Clapp, Joshua D; Beck, J Gayle

    2017-07-01

    Several factors have been linked to the severity of posttraumatic distress, although retrospective designs in much of the literature limit conclusions regarding the temporal relation between risk factors and corresponding symptoms. To address these concerns, the current project employed an analog trauma paradigm to assess the impact of background characteristics, stress response, and post-stressor affect regulation on subjective distress and intrusive memories experienced during the subsequent processing of emotional stimuli. University students (N = 184; 56% female, 42% White/Non-Hispanic) were shown graphic scenes of a televised suicide. Physiological activation was recorded during exposure with emotion ratings collected following the film. Participants then viewed a sadness- or humor-eliciting prime under instructions to inhibit or naturally express emotion. Intrusions experienced during the priming film and residual distress at study's conclusion were rated prior to debriefing. Hierarchical regression identified reductions in emotional valence as a robust predictor of intrusions and distress. Sympathetic activation and exposure to the sadness prime were associated with intrusion frequency, whereas attenuated parasympathetic response predicted intrusion intensity. Expressive inhibition demonstrated a unique association with residual distress. Results suggest peritraumatic processes and post-exposure factors may hold more prominent relations with immediate trauma-related distress as compared to pre-existing survivor characteristics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Diabetes, Triglyceride Levels, and Other Risk Factors for Glaucoma in the National Health and Nutrition Examination Survey 2005–2008

    Science.gov (United States)

    Ko, Fang; Boland, Michael V.; Gupta, Priya; Gadkaree, Shekhar K.; Vitale, Susan; Guallar, Eliseo; Zhao, Di; Friedman, David S.

    2016-01-01

    Purpose To determine risk factors for glaucoma in a population-based study in the United States. Methods Participants age 40 and older from the National Health and Nutrition Examination Survey underwent questionnaires, physical examination, laboratory tests, and vision tests including fundus imaging. Glaucoma was determined based on expert grading of fundus photographs. Regression modeling of glaucoma risk factors was performed. Results Participants with glaucoma (172) were older (mean age 68.1 [95% confidence interval (CI) 65.6–70.7] vs. 56.4 years [95% CI 55.6–57.2, P < 0.001]), likely to have less than high school education (25.1% vs. 18.1%, P = 0.05), to have diabetes (23.1% vs. 10.8%, P < 0.001), to have central obesity (72.5% vs. 60.7%, P = 0.01), to have systolic hypertension (30.3% vs. 20.1%, P = 0.01), to have diastolic hypotension (30.3% vs. 13.9%, P < 0.001), and to be nonsmokers (91.0% vs. 79.3%, P = 0.002). Sex, poverty, access to health care, fasting glucose, insulin dependence, body mass index, cholesterol levels, diastolic hypertension, systolic hypotension, obstructive sleep apnea, and marijuana were not associated with glaucoma. Multivariable modeling showed associations between glaucoma and older age (odds ratio [OR] 1.09 per year, 95% CI 1.04–1.14), black race (OR 4.40, 95% CI 1.71–11.30), and poverty (OR 3.39, 95% CI 1.73–6.66). Diabetes was no longer associated with glaucoma after adjustment for triglyceride levels. Sex, education, insurance status, body mass index, blood pressure, obstructive sleep apnea, and smoking were not associated with glaucoma. Conclusions People who are older, of black race, and with lower income levels have a higher prevalence of glaucoma. A novel association between diabetes, triglyceride levels, and glaucoma is also identified. PMID:27111561

  9. Origins of pottery technology in the ancient Near East: an examination of the technological and socioeconomic factors that contributed to the innovation and widespread use of pottery

    OpenAIRE

    Holdridge, Genevieve

    2004-01-01

    Ankara : The Department of Archaeology and History of Art of Bilkent Univ., 2004. Thesis (Master's) -- Bilkent University, 2004. Includes bibliographical references leaves 159-177. The objective of this thesis is to research the invention and innovation of pottery technology in the Pre-Pottery Neolithic B, in particular the Late and Final PrePottery Neolithic B and Early Pottery Neolithic in the Near East. My approach will involve examining the various factors that are invol...

  10. A cross-sectional study examining factors related to critical thinking in nursing.

    Science.gov (United States)

    Lang, Gary Morris; Beach, Nick Lee; Patrician, Patricia A; Martin, Cheryl

    2013-01-01

    The purpose of this study was to examine critical thinking skills among registered nurses who work in a military hospital. Sixty-five nurses were administered the Health Sciences Reasoning Test to obtain scores in inductive reasoning, deductive reasoning, interpretation, analysis, and evaluation skills. Results showed no significant association between critical thinking skills and years of experience; however, differences were identified among racial/ethnic groups. It is hoped that findings from this study create a platform for dialogue among staff development nurses who are best situated to develop strategies that address these issues.

  11. Examination of factors that lead to complications for new home parenteral nutrition patients.

    Science.gov (United States)

    de Burgoa, Lori Jeris; Seidner, Douglas; Hamilton, Cindy; Stafford, Judy; Steiger, Ezra

    2006-01-01

    Home parenteral nutrition carries a risk of infectious, metabolic, and mechanical complications that cause significant morbidity and mortality. This study investigated the incidence and the causative factors of these complications that occur within the first 90 days after discharge from the hospital to home. Data were prospectively collected and analyzed for 97 adult patients. A complication developed in one third of the patients, and the majority required rehospitalization. Infectious complications were the most prevalent, followed by mechanical and then metabolic complications. The authors describe their methods of collecting data in a quantifiable manner with the ultimate goal of improving patient outcomes.

  12. Optimising women's diets. An examination of factors that promote healthy eating and reduce the likelihood of unhealthy eating.

    Science.gov (United States)

    Williams, Lauren K; Thornton, Lukar; Crawford, David

    2012-08-01

    The majority of nutrition promotion research that has examined the determinants of unhealthy or healthy dietary behaviours has focused on factors that promote consumption of these foods, rather than factors that may both promote healthy eating and buffer or protect consumption of unhealthy foods. The purpose of this paper is to identify factors that both promote healthy eating and also reduce the likelihood of eating unhealthily amongst women. A community sample of 1013 Australian women participated in a cross-sectional self-report survey that assessed factors associated with diet and obesity. Multiple logistic regressions were used to examine the associations between a range of individual, social and environmental factors and aspects of both healthy and unhealthy eating, whilst controlling for key covariates. Results indicated that women with high self efficacy for healthy eating, taste preferences for fruit and vegetables, family support for healthy eating and the absence of perceived barriers to healthy eating (time and cost) were more likely to consume components of a healthy diet and less likely to consume components of a unhealthy diet. Optimal benefits in overall diet quality amongst women may be achieved by targeting factors associated with both healthy and unhealthy eating in nutrition promotion efforts. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Implementing an Online Curriculum for Medical Education: Examining the Critical Factors for Success

    Science.gov (United States)

    Olson, Bradley G.; Mata, Marvin; Koszalka, Tiffany A.

    2013-01-01

    Purpose: The Department of Pediatrics at SUNY Upstate Medical University in collaboration with the Instructional Design, Development, and Evaluation Department in Syracuse University's School of Education recently undertook a curricular reform effort that included translation of the residency program's annual core didactic lecture series…

  14. Examination of Lifestyle Behaviors and Cardiometabolic Risk Factors in University Students Enrolled in Kinesiology Degree Programs.

    Science.gov (United States)

    Many, Gina M; Lutsch, Andrea; Connors, Kimberly E; Shearer, Jane; Brown, Haley C; Ash, Garrett; Pescatello, Linda S; Gordish-Dressman, Heather; Barfield, Whitney; Dubis, Gabriel; Houmard, Joseph A; Hoffman, Eric P; Hittel, Dustin S

    2016-04-01

    Preventing physical inactivity and weight gain during college is critical in decreasing lifelong obesity and associated disease risk. As such, we sought to compare cardiometabolic risk factors and lifestyle behaviors between college students enrolled in kinesiology and non-kinesiology degree programs to assess whether health and exercise degree programs may influence health behaviors and associated disease risk outcomes. Anthropometrics, fasting blood glucose, insulin, lipid profiles and HbA1c%, blood pressure, and peak oxygen consumption (V[Combining Dot Above]O2peak) were assessed in 247 healthy college students. The homeostasis model assessment of insulin sensitivity (HOMA) was calculated using glucose and insulin levels. Self-reported physical activity from the Paffenbarger questionnaire was collected to estimate the average caloric expenditure due to different types of physical activities. Despite no significant differences in body mass index or waist circumference between groups, kinesiology majors presented with ∼20% lower fasting insulin levels and HOMA (p = 0.01; p Kinesiology majors reported increased weekly participation in vigorous-intensity sport and leisure activities and, on average, engaged in >300 metabolic equivalent-h·wk, whereas non-kinesiology majors engaged in kinesiology degree programs display improved healthy behaviors and associated outcomes (parameters of glucose homeostasis). Practical outcomes of this research indicate that implementing components of a comprehensive kinesiology curriculum encourages improved health behaviors and associated cardiometabolic risk factors.

  15. Recovery assessment scale: Examining the factor structure of the German version (RAS-G) in people with schizophrenia spectrum disorders.

    Science.gov (United States)

    Cavelti, M; Wirtz, M; Corrigan, P; Vauth, R

    2017-03-01

    The recovery framework has found its way into local and national mental health services and policies around the world, especially in English speaking countries. To promote this process, it is necessary to assess personal recovery validly and reliably. The Recovery Assessment Scale (RAS) is the most established measure in recovery research. The aim of the current study is to examine the factor structure of the German version of the RAS (RAS-G). One hundred and fifty-six German-speaking clients with schizophrenia or schizoaffective disorder from a community mental health service completed the RAS-G plus measures of recovery attitudes, self-stigma, psychotic symptoms, depression, and functioning. A confirmatory factor analysis of the original 24-item RAS version was conducted to examine its factor structure, followed by reliability and validity testing of the extracted factors. The CFA yielded five factors capturing 14 items which showed a substantial overlap with the original subscales Personal Confidence and Hope, Goal and Success Orientation, Willingness to Ask for Help, Reliance on Others, and No Domination by Symptoms. The factors demonstrated mean to excellent reliability (0.59-0.89) and satisfactory criterial validity by positive correlations with measures of recovery attitudes and functioning, and negative correlations with measures of self-stigma, and psychotic and depressive symptoms. The study results are discussed in the light of other studies examining the factor structure of the RAS. Overall, they support the use of the RAS-G as a means to promote recovery oriented services, policies, and research in German-speaking countries. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  16. Trajectories of internalizing problems in war-affected Sierra Leonean youth: examining conflict and postconflict factors.

    Science.gov (United States)

    Betancourt, Theresa S; McBain, Ryan; Newnham, Elizabeth A; Brennan, Robert T

    2013-01-01

    Three waves of data from a prospective longitudinal study in Sierra Leone were used to examine internalizing trajectories in 529 war-affected youth (ages 10-17 at baseline; 25% female). Latent class growth analyses identified 4 trajectories: A large majority of youth maintained lower levels of internalizing problems (41.4%) or significantly improved over time (47.6%) despite very limited access to care, but smaller proportions continued to report severe difficulties 6 years postwar (4.5%) or their symptoms worsened (6.4%). Continued internalizing problems were associated with loss of a caregiver, family abuse and neglect, and community stigma. Despite the comparative resilience of most war-affected youth in the face of extreme adversity, there remains a compelling need for interventions that address family- and community-level stressors.

  17. Examining the Status and Impact Factor of Muslim Scientific Journals in ISI Database: A Bibliometric Study

    Directory of Open Access Journals (Sweden)

    Nurrollah Karami

    2010-09-01

    Full Text Available This paper employs bibliometric method for analyzing the status of journals published in muslim countries in the Journal of Citation Report, an ISI maintained database. The findings indicated that there are 37 journals from 12 muslim countries indexed in JCR. Turkey leads with nine journals indexed. Inter-disciplinary journals constitute the subject area of six journals. Bentham Science Publishers is the most active by publishing 7 journals. Turkey is the only muslim country that has two journals in social sciences. English is the main language in 86.5 percent of the journals studied. Turkish Journal of Earth Sciences has the highest impact factor. The highest citations and citation half-life belonged to Chemical National Compendium from Uzbekistan.

  18. Examining the Factors Affecting PDA Acceptance among Physicians: An Extended Technology Acceptance Model.

    Science.gov (United States)

    Basak, Ecem; Gumussoy, Cigdem Altin; Calisir, Fethi

    2015-01-01

    This study aims at identifying the factors affecting the intention to use personal digital assistant (PDA) technology among physicians in Turkey using an extended Technology Acceptance Model (TAM). A structural equation-modeling approach was used to identify the variables that significantly affect the intention to use PDA technology. The data were collected from 339 physicians in Turkey. Results indicated that 71% of the physicians' intention to use PDA technology is explained by perceived usefulness and perceived ease of use. On comparing both, the perceived ease of use has the strongest effect, whereas the effect of perceived enjoyment on behavioral intention to use is found to be insignificant. This study concludes with the recommendations for managers and possible future research.

  19. He Said, She Said: Examining Parental Concordance on Home Environment Factors and Adolescent Health Behaviors and Weight Status

    Science.gov (United States)

    Berge, Jerica M.; MacLehose, Richard F; Meyer, Craig; Didericksen, Katharine; Loth, Katie A.; Neumark-Sztainer, Dianne

    2015-01-01

    Introduction Few studies have examined concordance/discordance between caregivers to identify whether caregivers see familial and parental factors in the home environment similarly or differently and whether the agreement or disagreement is related to adolescent obesity risk. Answers to these questions are important and may inform whether family-based childhood obesity interventions need to target both parents. Objective The main objective of the study is to examine whether and how parental concordance/discordance on factors in the home environment (e.g., importance of family meals, parent feeding practices, encouraging child physical activity, limit setting on child screen time) are associated with adolescent health behaviors and weight status. Design Data from two linked population-based studies were used in cross-sectional analyses. Linear regression models examined associations between parental concordance/discordance on home environment factors and adolescents’ health behaviors and weight status. Participant/Settings Racially/ethnically and socioeconomically diverse adolescents (n=1,052; 54% girls; mean age = 14.3 years) and their parents (n=2,104; 52% female; mean age = 41.0 years) from Minneapolis and St. Paul, Minnesota participated in the study. Anthropometric assessments and surveys were completed at school by adolescents and surveys were completed at home by parents. Results Parental concordance on home environment factors was high for some factors (e.g., 68% concordance on not pressuring adolescent to eat) and low for other factors (e.g., 2% concordance on parent engaging in physically activity with child 4+ hours/week). Parental concordance on positive home environment factors (e.g., frequency of family meals) was associated with more adolescent healthful eating patterns and hours of physical activity (p < 0.05), but not consistently. When parents were discordant, adolescents had higher consumption of fast food and more unhealthy weight control

  20. Overweight and Obesity in Italian Adolescents: Examined Prevalence and Socio-Demographic Factors.

    Science.gov (United States)

    Galfo, Myriam; D'Addezio, Laura; Censi, Laura; Roccaldo, Romana; Martone, Deborah

    2016-12-01

    This study aimed to evaluate the prevalence of overweight and obesity derived from measured data of weight and height in a cross-sectional sample of adolescents in the Italian region of Lazio and to analyse their association with different socio-demographic factors. The study was conducted in a representative sample of 15-16-year-old adolescents recruited in secondary schools between December 2011 and May 2012. 369 adolescents were investigated. Body weight, height and waist circumference were measured. The BMI of each subject was calculated, and the prevalence of overweight and obesity was determined by age and sex using the IOTF reference values and WHO growth standards. Waist circumference/height ratio (WC/Ht) was calculated and the subjects were classified using the cut-off of 0.5: WC/Ht≥0.5 and WC/Htsocio-demographic characteristics were assessed via questionnaire. The percentages of overweight and obesity were high, 15.4% and 7.9%, respectively, with significant difference between males and females (19.1% vs. 12.6% for overweight and 11.1% vs. 5.3% for obese) using the IOFT reference. The ratio WC/Ht≥0.5 was observed in 12.7% of the sample (all the obese and 29.8% of the overweight subjects). Multiple logistic regression analysis indicated that gender, school municipality, mother's employment status, and family structure had a significant effect on ponderal status (overweight/obesity vs. normal weight). These findings show a high prevalence of body weight excess associated with socio-demographic factors in the Italian sample investigated, and the need for effective public health interventions to combact obesity with particular attention to disadvantaged adolescents.

  1. Examining trust factors in online food risk information: The case of unpasteurized or 'raw' milk.

    Science.gov (United States)

    Sillence, Elizabeth; Hardy, Claire; Medeiros, Lydia C; LeJeune, Jeffrey T

    2016-04-01

    The internet has become an increasingly important way of communicating with consumers about food risk information. However, relatively little is known about how consumers evaluate and come to trust the information they encounter online. Using the example of unpasteurized or raw milk this paper presents two studies exploring the trust factors associated with online information about the risks and benefits of raw milk consumption. In the first study, eye-tracking data was collected from 33 pasteurised milk consumers whilst they viewed six different milk related websites. A descriptive analysis of the eye-tracking data was conducted to explore viewing patterns. Reports revealed the importance of images as a way of capturing initial attention and foregrounding other features and highlighted the significance of introductory text within a homepage. In the second, qualitative study, 41 consumers, some of whom drank raw milk, viewed a selection of milk related websites before participating in either a group discussion or interview. Seventeen of the participants also took part in a follow up telephone interview 2 weeks later. The qualitative data supports the importance of good design whilst noting that balance, authorship agenda, the nature of evidence and personal relevance were also key factors affecting consumers trust judgements. The results of both studies provide support for a staged approach to online trust in which consumers engage in a more rapid, heuristic assessment of a site before moving on to a more in-depth evaluation of the information available. Findings are discussed in relation to the development of trustworthy online food safety resources.

  2. Examining Factors in the Research Institute on Addictions Self-Inventory (RIASI: Associations with Alcohol Use and Problems at Assessment and Follow-Up

    Directory of Open Access Journals (Sweden)

    Elisabeth Wells-Parker

    2009-11-01

    Full Text Available Impaired driving is a leading cause of alcohol-related deaths and injuries. Rehabilitation or remedial programs, involving assessment and screening of convicted impaired drivers to determine problem severity and appropriate programs, are an important component of society’s response to this problem. Ontario’s remedial program, Back on Track (BOT, involves an assessment process that includes administration of the Research Institute on Addictions Self-Inventory (RIASI to determine assignment to an education or treatment program. The purpose of this study is to identify factors within the RIASI and examine how factor scores are associated with alcohol use and problem indicators at assessment and six-month follow-up. The sample included 22,298 individuals who completed BOT from 2000 to 2005. Principal component factor analysis with varimax rotation was conducted on RIASI data and an eight factor solution was retained: (1 Negative Affect, (2 Sensation Seeking, (3 Alcohol-Quantity, (4 Social Conformity, (5 High Risk Lifestyle, (6 Alcohol Problems, (7 Interpersonal Competence, and (8 Family History. Regression analyses were conducted to examine associations between factors and alcohol and problem measures obtained at assessment and at follow-up. Most factors, except for Interpersonal Competence, were associated with more alcohol use and problems at assessment. A similar pattern was observed at 6-month follow-up, but interestingly some factors (Negative Affect, Sensation Seeking, Alcohol-Quantity and Family History predicted fewer days of alcohol use. The Interpersonal Competence factor was associated with significantly lower levels of alcohol use and problems at both assessment and follow-up. This work suggests that the RIASI provides information on several domains that have important relationships with alcohol problem severity and outcomes.

  3. Examining factors in the Research Institute on Addictions Self-Inventory (RIASI): Associations with alcohol use and problems at assessment and follow-up.

    Science.gov (United States)

    Mann, Robert E; Stoduto, Gina; Zalcman, Rosely Flam; Nochajski, Thomas H; Hall, Louise; Dill, Patricia; Wells-Parker, Elisabeth

    2009-11-01

    Impaired driving is a leading cause of alcohol-related deaths and injuries. Rehabilitation or remedial programs, involving assessment and screening of convicted impaired drivers to determine problem severity and appropriate programs, are an important component of society's response to this problem. Ontario's remedial program, Back on Track (BOT), involves an assessment process that includes administration of the Research Institute on Addictions Self-Inventory (RIASI) to determine assignment to an education or treatment program. The purpose of this study is to identify factors within the RIASI and examine how factor scores are associated with alcohol use and problem indicators at assessment and six-month follow-up. The sample included 22,298 individuals who completed BOT from 2000 to 2005. Principal component factor analysis with varimax rotation was conducted on RIASI data and an eight factor solution was retained: (1) Negative Affect, (2) Sensation Seeking, (3) Alcohol-Quantity, (4) Social Conformity, (5) High Risk Lifestyle, (6) Alcohol Problems, (7) Interpersonal Competence, and (8) Family History. Regression analyses were conducted to examine associations between factors and alcohol and problem measures obtained at assessment and at follow-up. Most factors, except for Interpersonal Competence, were associated with more alcohol use and problems at assessment. A similar pattern was observed at 6-month follow-up, but interestingly some factors (Negative Affect, Sensation Seeking, Alcohol-Quantity and Family History) predicted fewer days of alcohol use. The Interpersonal Competence factor was associated with significantly lower levels of alcohol use and problems at both assessment and follow-up. This work suggests that the RIASI provides information on several domains that have important relationships with alcohol problem severity and outcomes.

  4. The center for epidemiologic studies depression scale: a review with a theoretical and empirical examination of item content and factor structure.

    Directory of Open Access Journals (Sweden)

    R Nicholas Carleton

    Full Text Available BACKGROUND: The Center for Epidemiologic Studies Depression Scale (CES-D; Radloff, 1977 is a commonly used freely available self-report measure of depressive symptoms. Despite its popularity, several recent investigations have called into question the robustness and suitability of the commonly used 4-factor 20-item CES-D model. The goal of the current study was to address these concerns by confirming the factorial validity of the CES-D. METHODS AND FINDINGS: Differential item functioning estimates were used to examine sex biases in item responses, and confirmatory factor analyses were used to assess prior CES-D factor structures and new models heeding current theoretical and empirical considerations. Data used for the analyses included undergraduate (n = 948; 74% women, community (n = 254; 71% women, rehabilitation (n = 522; 53% women, clinical (n =84; 77% women, and National Health and Nutrition Examination Survey (NHANES; n = 2814; 56% women samples. Differential item functioning identified an item as inflating CES-D scores in women. Comprehensive comparison of the several models supported a novel, psychometrically robust, and unbiased 3-factor 14-item solution, with factors (i.e., negative affect, anhedonia, and somatic symptoms that are more in line with current diagnostic criteria for depression. CONCLUSIONS: Researchers and practitioners may benefit from using the novel factor structure of the CES-D and from being cautious in interpreting results from the originally proposed scale. Comprehensive results, implications, and future research directions are discussed.

  5. Examination of the Divergence in Trends for Adolescent Marijuana Use and Marijuana-specific Risk Factors in Washington State

    Science.gov (United States)

    Fleming, Charles B.; Guttmannova, Katarina; Cambron, Christopher; Rhew, Isaac C.; Oesterle, Sabrina

    2016-01-01

    Purpose As marijuana laws have become more permissive, survey data on adolescents in the United States have shown an increase in marijuana-specific risk factors, particularly in the proportion of youth who do not perceive marijuana use as harmful. Prevalence of marijuana use among youth, however, has changed little. Using representative data from Washington State, which has legalized medical and nonmedical marijuana for adults, we examined two competing hypotheses to account for this divergence in population trends. Methods Data were from 2000 – 2014 biennial Washington State surveys of 10th-grade students. First, we assessed whether associations between marijuana use and marijuana-specific risk factors have weakened over time. Second, we examined whether decreases in alcohol and cigarette use can account for the lack of expected increase in marijuana use prevalence. Results Despite stability in marijuana use prevalence, there were increases in marijuana-specific risk factors of low perceived harm, youth favorable attitudes about use, and perceived community attitudes favorable to use. Associations between marijuana use and marijuana-use predictors varied little across time; if anything, the positive association between low perceived harm and marijuana use grew stronger. Decreases in prevalence of alcohol and cigarette use largely accounted for stability in marijuana use during a period when marijuana risk factors increased. Conclusions Decreases in other types of substance use or in the underlying, common risk for substance use may have mitigated effects of increases in marijuana-specific risk factors. PMID:27318426

  6. An examination of some factors influencing creatine kinase in the blood of patients with muscular dystrophy.

    Science.gov (United States)

    Jackson, M J; Round, J M; Newham, D J; Edwards, R H

    1987-01-01

    The natural variability of plasma creatine kinase activity has been examined in patients suffering from muscular dystrophy and in normal subjects. The coefficient of variation of the plasma creatine kinase activities was found to be large (approximately 35%) in both patients with Duchenne muscular dystrophy and normal control subjects. A comparison of the plasma activities of creatine kinase with other muscle-derived enzymes suggests that the cause of this variability is changes in the release of enzymes from muscle. Data obtained concerning the effect of physical activity on plasma creatine kinase activity are contradictory, but several young patients with Duchenne muscular dystrophy and a very high creatine kinase activity (greater than 5000 IU/liter) showed a decreased activity following admission to hospital. An estimate of the rate of efflux of certain kinase from muscle has been made, indicating that young ambulant patients with Duchenne muscular dystrophy have a grossly elevated muscle creatine kinase efflux (495.0 +/- 61.3 IU/kg muscle/hr) compared to control subjects (1.4 +/- 0.5 IU/kg muscle/hr).

  7. Readability, suitability, and characteristics of asthma action plans: examination of factors that may impair understanding.

    Science.gov (United States)

    Yin, H Shonna; Gupta, Ruchi S; Tomopoulos, Suzy; Wolf, Michael S; Mendelsohn, Alan L; Antler, Lauren; Sanchez, Dayana C; Lau, Claudia Hillam; Dreyer, Benard P

    2013-01-01

    Recognition of the complexity of asthma management has led to the development of asthma treatment guidelines that include the recommendation that all pediatric asthma patients receive a written asthma action plan. We assessed the readability, suitability, and characteristics of asthma action plans, elements that contribute to the effectiveness of action plan use, particularly for those with limited literacy. This was a descriptive study of 30 asthma action plans (27 state Department of Health (DOH)-endorsed, 3 national action plans endorsed by 6 states). (1) readability (as assessed by Flesch Reading Ease, Flesch-Kincaid, Gunning Fog, Simple Measure of Gobbledygook, Forcast), (2) suitability (Suitability Assessment of Materials [SAM], adequate: ≥ 0.4; unsuitable: typography (30.0%), learning stimulation/motivation (26.7%), and graphics (13.3%). There were no statistically significant differences between the average grade level or SAM score of state DOH developed action plans and those from or adapted from national organizations. Plans varied with respect to terms used, symptoms included, and recommended actions. Specific improvements in asthma action plans could maximize patient and parent understanding of appropriate asthma management and could particularly benefit individuals with limited literacy skills.

  8. Examining the Key Factors Affecting e-Service Quality of Small Online Apparel Businesses in Malaysia

    Directory of Open Access Journals (Sweden)

    Che Nawi Noorshella

    2015-04-01

    Full Text Available e-Service quality (eSQ is increasingly recognized as an important aspect, as well as the key to determining the competitive advantage and factor in the long-term retention of firms operating online. This study, therefore, is aimed at identifying the key determinants of eSQ among the small online apparel businesses in Malaysia. This study used a cross-sectional design, and data were collected from 765 customers who purchased apparel online at the point-of-purchase. Findings of this study indicate that “product information quality,” “website design,” “security and privacy,” and “expected consumer service” are the key determinants of eSQ among small online apparel businesses in Malaysia. The implication for the owner-managers of the apparel businesses in Malaysia is that they must be aware of the significance of the key eSQ indicators while designing their businesses, to attract and retain customers.

  9. Examination of factors predicting secondary students' interest in tertiary STEM education

    Science.gov (United States)

    Chachashvili-Bolotin, Svetlana; Milner-Bolotin, Marina; Lissitsa, Sabina

    2016-02-01

    Based on the Social Cognitive Career Theory (SCCT), the study aims to investigate factors that predict students' interest in pursuing science, technology, engineering, and mathematics (STEM) fields in tertiary education both in general and in relation to their gender and socio-economic background. The results of the analysis of survey responses of 2458 secondary public school students in the fifth-largest Israeli city indicate that STEM learning experience positively associates with students' interest in pursuing STEM fields in tertiary education as opposed to non-STEM fields. Moreover, studying advanced science courses at the secondary school level decreases (but does not eliminate) the gender gap and eliminates the effect of family background on students' interest in pursuing STEM fields in the future. Findings regarding outcome expectations and self-efficacy beliefs only partially support the SCCT model. Outcome expectations and self-efficacy beliefs positively correlate with students' entering tertiary education but did not differentiate between their interests in the fields of study.

  10. Examining Factors That Impact Inpatient Management of Diabetes and the Role of Insulin Pen Devices.

    Science.gov (United States)

    Smallwood, Chelsea; Lamarche, Danièle; Chevrier, Annie

    2017-02-01

    Insulin administration in the acute care setting is an integral component of inpatient diabetes management. Although some institutions have moved to insulin pen devices, many acute care settings continue to employ the vial and syringe method of insulin administration. The aim of this study was to evaluate the impact of insulin pen implementation in the acute care setting on patients, healthcare workers and health resource utilization. A review of published literature, including guidelines, was conducted to identify how insulin pen devices in the acute care setting may impact inpatient diabetes management. Previously published studies have revealed that insulin pen devices have the potential to improve inpatient management through better glycemic control, increased adherence and improved self-management education. Furthermore, insulin pen devices may result in cost savings and improved safety for healthcare workers. There are benefits to the use of insulin pen devices in acute care and, as such, their implementation should be considered.

  11. Further examination of factors that influence preference for positive versus negative reinforcement.

    Science.gov (United States)

    Kodak, Tiffany; Lerman, Dorothea C; Volkert, Valerie M; Trosclair, Nicole

    2007-01-01

    Factors that influence choice between qualitatively different reinforcers (e.g., a food item or a break from work) are important to consider when arranging treatments for problem behavior. Previous findings indicate that children who engage in problem behavior maintained by escape from demands may choose a food item over the functional reinforcer during treatment (DeLeon, Neidert, Anders, & Rodriguez-Catter, 2001; Lalli et al., 1999). However, a number of variables may influence choice between concurrently available forms of reinforcement. An analogue for treatment situations in which positive reinforcement for compliance is in direct competition with negative reinforcement for problem behavior was used in the current study to evaluate several variables that may influence choice. Participants were 5 children who had been diagnosed with developmental disabilities and who engaged in problem behavior maintained by escape from demands. In the first phase, the effects of task preference and schedule of reinforcement on choice between a 30-s break and a high-preference food item were evaluated. The food item was preferred over the break, regardless of the preference level of the task or the reinforcement schedule, for all but 1 participant. In the second phase, the quality of the break was manipulated by combining escape with toys, attention, or both. Only 1 participant showed preference for the enriched break. In the third phase, choice of a medium- or low-preference food item versus the enriched break was evaluated. Three of 4 participants showed preference for the break over the less preferred food item. Results extend previous research by identifying some of the conditions under which individuals who engage in escape-maintained behavior will prefer a food reinforcer over the functional one.

  12. Family History, Diabetes, and Other Demographic and Risk Factors Among Participants of the National Health and Nutrition Examination Survey 1999–2002

    Directory of Open Access Journals (Sweden)

    Debra Duquette, MS, CGC

    2005-03-01

    Full Text Available Introduction Family history of diabetes has been recognized as an important risk factor of the disease. Family medical history represents valuable genomic information because it characterizes the combined interactions between environmental, behavioral, and genetic factors. This study examined the strength and effect of having a family history of diabetes on the prevalence of self-reported, previously diagnosed diabetes among adult participants of the National Health and Nutrition Examination Survey 1999–2002. Methods The study population included data from 10,283 participants aged 20 years and older. Gender, age, race/ethnicity, poverty income ratio, education level, body mass index, and family history of diabetes were examined in relation to diabetes status. Diabetes prevalence estimates and odds ratios of diabetes were calculated based on family history and other factors. Results The prevalence of diabetes among individuals who have a first-degree relative with diabetes (14.3% was significantly higher than that of individuals without a family history (3.2%, corresponding to a crude odds ratio of five. Both prevalence and odds ratio estimates significantly increased with the number of relatives affected with diabetes. Family history was also associated with several demographic and risk factors. Conclusion Family history of diabetes was shown to be a significant predictor of diabetes prevalence in the adult U.S. population. We advocate the inclusion of family history assessment in public health prevention and screening programs as an inexpensive and valuable source of genomic information and measure of diabetes risk.

  13. EXAMINATION OF FACTORS INFLUENCING THE VARIABILITY OF YEAST AMOUNT IN THE CONTEXT OF PH CHANGES IN BOTTLED WINES

    OpenAIRE

    Ladislav Mura; Ľubomír Lopašovský; Dagmar Kozelová; Lucia Zeleňáková; Eva Matejková

    2011-01-01

    Aim of this paper was to examine of factors (manufacturer, temperature and storage time) influencing the variability of yeast amount and pH changes in bottled white wines. It was confirmed that wine coming from the business network was better quality in contract to domestic wine. We have assumed that domestic wine was contaminated during the manufacturing process, while the most probable reason was imperfect filtration of wine, or its contamination during the bottling. The results showed that...

  14. Risk Factors for Possible Dementia Using the Hopkins Verbal Learning Test and the Mini-Mental State Examination in Shanghai

    Directory of Open Access Journals (Sweden)

    Xin Xu

    2015-11-01

    Full Text Available Using a combination of the Hopkins Verbal Learning Test (HVLT and the Mini-Mental State Examination (MMSE, we investigated the prevalence of possible dementia (DEM in community-dwelling elderly in Shanghai. Subsequently, we investigated significant risk factors for DEM and generated a DEM self-checklist for early DEM detection and case management. We found that among a total of 521 participants using a HVLT cut-off score of <19 and a MMSE cut-off score of <24, a total of 69 DEM cases were identified. Risk factors, such as advanced age (≥68 years, low education (no or primary level, self-reported history of hypertension, and self-reported subjective memory complaints (SMC were significantly predictive of DEM. The presence of ≥3 out of four of the above mentioned risk factors can effectively discriminate DEM cases from non-DEM subjects.

  15. A model inter-comparison study to examine limiting factors in modelling Australian tropical savannas

    Directory of Open Access Journals (Sweden)

    R. Whitley

    2015-12-01

    Full Text Available Savanna ecosystems are one of the most dominant and complex terrestrial biomes that derives from a distinct vegetative surface comprised of co-dominant tree and grass populations. While these two vegetation types co-exist functionally, demographically they are not static, but are dynamically changing in response to environmental forces such as annual fire events and rainfall variability. Modelling savanna environments with the current generation of terrestrial biosphere models (TBMs has presented many problems, particularly describing fire frequency and intensity, phenology, leaf biochemistry of C3 and C4 photosynthesis vegetation, and root water uptake. In order to better understand why TBMs perform so poorly in savannas, we conducted a model inter-comparison of 6 TBMs and assessed their performance at simulating latent energy (LE and gross primary productivity (GPP for five savanna sites along a rainfall gradient in northern Australia. Performance in predicting LE and GPP was measured using an empirical benchmarking system, which ranks models by their ability to utilise meteorological driving information to predict the fluxes. On average, the TBMs performed as well as a multi-linear regression of the fluxes against solar radiation, temperature and vapour pressure deficit, but were outperformed by a more complicated nonlinear response model that also included the leaf area index (LAI. This identified that the TBMs are not fully utilising their input information effectively in determining savanna LE and GPP, and highlights that savanna dynamics cannot be calibrated into models and that there are problems in underlying model processes. We identified key weaknesses in a model's ability to simulate savanna fluxes and their seasonal variation, related to the representation of vegetation by the models and root water uptake. We underline these weaknesses in terms of three critical areas for development. First, prescribed tree-rooting depths must be

  16. A model inter-comparison study to examine limiting factors in modelling Australian tropical savannas

    Science.gov (United States)

    Whitley, Rhys; Beringer, Jason; Hutley, Lindsay B.; Abramowitz, Gab; De Kauwe, Martin G.; Duursma, Remko; Evans, Bradley; Haverd, Vanessa; Li, Longhui; Ryu, Youngryel; Smith, Benjamin; Wang, Ying-Ping; Williams, Mathew; Yu, Qiang

    2016-06-01

    The savanna ecosystem is one of the most dominant and complex terrestrial biomes, deriving from a distinct vegetative surface comprised of co-dominant tree and grass populations. While these two vegetation types co-exist functionally, demographically they are not static but are dynamically changing in response to environmental forces such as annual fire events and rainfall variability. Modelling savanna environments with the current generation of terrestrial biosphere models (TBMs) has presented many problems, particularly describing fire frequency and intensity, phenology, leaf biochemistry of C3 and C4 photosynthesis vegetation, and root-water uptake. In order to better understand why TBMs perform so poorly in savannas, we conducted a model inter-comparison of six TBMs and assessed their performance at simulating latent energy (LE) and gross primary productivity (GPP) for five savanna sites along a rainfall gradient in northern Australia. Performance in predicting LE and GPP was measured using an empirical benchmarking system, which ranks models by their ability to utilise meteorological driving information to predict the fluxes. On average, the TBMs performed as well as a multi-linear regression of the fluxes against solar radiation, temperature and vapour pressure deficit but were outperformed by a more complicated nonlinear response model that also included the leaf area index (LAI). This identified that the TBMs are not fully utilising their input information effectively in determining savanna LE and GPP and highlights that savanna dynamics cannot be calibrated into models and that there are problems in underlying model processes. We identified key weaknesses in a model's ability to simulate savanna fluxes and their seasonal variation, related to the representation of vegetation by the models and root-water uptake. We underline these weaknesses in terms of three critical areas for development. First, prescribed tree-rooting depths must be deep enough

  17. Impact on total population health and societal cost-effectiveness of including tumour necrosis factor- antagonists in management of ankylosing spondylitis: a dynamic population modelling study

    NARCIS (Netherlands)

    A. Tran-Duy (An); A. Boonen (Annelies); M.A.F.J. van de Laar (Martin); J.L. Severens (Hans)

    2015-01-01

    markdownabstractAbstract Background: Sequential treatment of ankylosing spondylitis (AS) that includes tumour necrosis factor-α antagonists (anti-TNF agents) has been applied in most of the Western countries. Existing cost-effectiveness (CE) models almost exclusively presented the incremental

  18. Why is psychiatric nursing not the preferred option for nursing students: A cross-sectional study examining pre-nursing and nursing school factors.

    Science.gov (United States)

    Ong, Hui Lin; Seow, Esmond; Chua, Boon Yiang; Xie, Huiting; Wang, Jia; Lau, Ying Wen; Chong, Siow Ann; Subramaniam, Mythily

    2017-05-01

    There is a shortage of nurses working in the mental health field globally. The aim of the present study was to examine Singapore nursing students' attitudes towards specializing in psychiatric nursing by examining the pre-nursing and nursing school factors as well as attitudes towards psychiatry and personality traits. A cross-sectional online survey was conducted with 500 nursing students from four nursing institutions in Singapore. Students' attitudes towards psychiatry (ATP-18), perception of psychiatric nursing career aspects relative to other fields, and personality traits (mini-IPIP) were assessed. The main outcome measure was likelihood of specializing in psychiatric nursing. Logistic regression was used to examine the combined effect of factors upon the outcome. Twenty-six students (5.2%) rated "definitely decided to do" psychiatric nursing. Pre-nursing school factors associated with choosing psychiatry included ethnicity, current education, parents' wishes, having personal/family experience of mental illness, prior work experience, interest in psychiatric nursing and psychology module taken prior to current school admission. Nursing school factors such as teaching methods and clinical exposure were not associated with choosing psychiatric nursing. Positive attitudes towards psychiatry, perception of better career aspects in psychiatric nursing relative to other fields, and the personality traits of extraversion and intellect/imagination were associated with likelihood of choosing psychiatric nursing. Logistic regression revealed Malay (OR: 1.90, 1.14-3.16, p=0.013) and Indian ethnicity (OR: 2.56, 1.32-4.96, p=0.005), interest in psychiatry (OR: 22.56, 8.22-61.92, pstudents choosing psychiatric nursing. The selection of psychiatry as a specialty by nursing students was affected by pre-nursing school factors. Taking these factors into consideration may improve recruitment and alleviate the shortages in the psychiatric nursing field. Copyright © 2017 The

  19. Gas-phase and Ar-matrix SQM scaling factors for various DFT functionals with basis sets including polarization and diffuse functions.

    Science.gov (United States)

    Fábri, Csaba; Szidarovszky, Tamás; Magyarfalvi, Gábor; Tarczay, György

    2011-05-12

    Scaling factors for Pulay's scaled quantum mechanical (SQM) scheme have been determined for four different widely used DFT functionals (PBE, B3LYP, B3PW91, and M06-2X) and for two basis sets (6-31++G** and aug-cc-pVTZ) by fitting computed results to 347 fundamental experimental vibrational frequencies of 33 molecules. Measurements in the gas phase and in solid argon matrices were used independently in the fitting procedure in order to provide a simple method of estimating matrix shifts. The accuracy of the new scaling factors is demonstrated on test molecules including hydrogen-bonded systems and molecules containing chlorine and sulfur atoms.

  20. An examination of sociodemographic, health, psychological factors, and fruit and vegetable consumption among overweight and obese U.S. veterans.

    Science.gov (United States)

    Ko, Linda K; Allicok, Marlyn; Campbell, Marci K; Valle, Carmina G; Armstrong-Brown, Janelle; Carr, Carol; Dundon, Margaret; Anthony, Tammy

    2011-11-01

    A diet high in fruits and vegetables (F&Vs) is associated with decreased risk for cardiovascular disease, diabetes, and cancer. This study investigated the relationship between sociodemographic, health, and psychosocial factors and F&V consumption among overweight and obese U.S. veterans. Participants were recruited from two Veterans Affairs medical center sites in 2005. Two hundred eighty-nine participants completed a self-administered survey. Bivariate and multivariate linear regression models were built to examine the association between sociodemographic, health, and psychosocial variables and F&V consumption. Older age (B = 0.01; p obese conditions. Age, race, tobacco use, and psychosocial factors should be considered carefully when developing dietary interventionsamong overweight ana obese U.S. veterans.

  1. Weight pressures in sport: examining the factor structure and incremental validity of the weight pressures in sport - females.

    Science.gov (United States)

    Reel, Justine J; Petrie, Trent A; SooHoo, Sonya; Anderson, Carlin M

    2013-04-01

    Due to pressures within the sport environment, such as from coaches, teammates, uniforms and judges, female athletes may develop unhealthy eating practices to lose weight or change their body size/shape to become more competitive and meet societal and sport-related physique ideals. However, up until the development of the Weight Pressures in Sport for Females (WPS-F; Reel, SooHoo, Petrie, Greenleaf, & Carter, 2010) there was no way to quantify sport-specific weight pressures with female athletes. In this study, the psychometric properties of the scale were further examined using a sample of 414 female collegiate athletes. Sample 1 [n=207; M=19.27 years; SD=1.16] and Sample 2 [n=207; M=19.19 years; SD=1.66] participants were of a similar age and were used for exploratory and confirmatory analyses respectively. A two factor structure was confirmed and it was established that the scale was unique from general sociocultural pressures that all women experience, predicting female athletes' internalization, body dissatisfaction, dietary intent, and bulimic symptomatology. Specifically, the following factors, Coach and Sport Pressures about Weight (Factor 1) and Pressures Regarding Appearance and Performance (Factor 2), were found to have strong internal consistency and the emerging reliable and valid WPS-F has practical implications for screening and identifying weight-related sport pressures within female athletes. WPS-F can also serve to educate sport professionals about environmental pressures so that disordered eating and body image disturbances can be prevented.

  2. Prevalence and risk factors of chronic otitis media: the Korean National Health and Nutrition Examination Survey 2010-2012.

    Directory of Open Access Journals (Sweden)

    Mina Park

    Full Text Available The performance of nationwide studies of chronic otitis media (COM in adults has been insufficient in Korea. We evaluated the prevalence and risk factors of COM in Korea.This study was conducted using data from the fifth Korean National Health and Nutrition Examination Survey (n = 23,621. After excluding the subjects under 20 year old and suffered from cancers, 16,063 patients were evaluated for COM. Participants underwent a medical interview, physical examination, endoscopic examination, and blood and urine test. COM was diagnosed by trained residents in the Department of Otorhinolaryngology using an ear, nose, and throat questionnaire and otoendoscopy findings. Data on the presence and absence of COM were collected. Multivariate logistic regression analyses were performed to identify its risk factors.Of the 16,063 participants aged above 20 year old, the weighted prevalence of COM was 3.8%. In the multivariate analyses, the following factors showed high odds ratios (ORs for COM: pulmonary tuberculosis (adjusted OR, 1.78; 95% confidence interval [CI], 1.06-3.01, chronic rhinosinusitis (adjusted OR, 1.87; 95% CI, 1.17-2.98, mild hearing impairment (adjusted OR, 1.95; 95% CI, 1.34-2.85, moderate hearing impairment (adjusted OR, 4.00; 95% CI, 2.21-7.22, tinnitus (adjusted OR, 1.82; 95% CI, 1.34-2.49, increased hearing thresholds in pure tone audiometry in the right ear (adjusted OR, 1.02; 95% CI, 1.01-1.03, and left ear (adjusted OR, 1.03; 95% CI, 1.02-1.04. The following factors showed low odds ratios for COM: hepatitis B (adjusted OR, 0.28; 95% CI, 0.08-0.94 and rhinitis (adjusted OR, 0.60; 95% CI, 0.42-0.88. In addition, high levels of vitamin D, lead, and cadmium, EQ-5D index; and low red blood cell counts were associated with development of COM (Student's t-test, P < 0.01.Our population-based study showed that COM is not rare in Korea, and its development may be associated with various host and environmental factors. Further research on its

  3. Organizational Leadership Assessment in Servant Organizations: Adaptation for Turkish Culture, Language Validity and Examination of Factor Structure

    Directory of Open Access Journals (Sweden)

    Hakkı KAHVECİ

    2012-06-01

    Full Text Available The purpose of this study is to adapt Laub’s (1999 Organizational Leadership Assessment in Servant Organizations to Turkish literaturate on servant leadership. Validity and reliability analyzes were conducted. The original instrument included 60 questions and six dimensions. Data was collected from primaryschool teachers in Eskişehir and Balıkesir. Descriptive statistics and exploratory factor analyis were used to analyze the data. Resulst indicated that, a valid and relaible instrument included 54 questions with two dimensions.

  4. Development of a Survey to Examine the Factors that Motivate Secondary Education Teachers' Use of Problem-based Learning (PBL)

    Science.gov (United States)

    Lao, Huei-Chen

    In this quantitative study, a survey was developed and administered to middle and high school teachers to examine what factors motivated them to implement problem-based learning (PBL). Using Expectancy-Value Theory by Eccles et al. (1983) and Self-Determination Theory by Ryan and Deci (2000b) as the theoretical framework, this instrument measured respondents' perceived competence, support for autonomy and relatedness, and value and cost they placed on implementing PBL. Data analyses indicated that the instrument had good reliability. A 3-factor structure was established by exploratory factor analysis which confirmed the construct validity of the instrument. Value of PBL to teachers and their students was the most dominant factor that motivated teachers to implement it. The second most important factor was their self-efficacy and anxiety about failing this pedagogy, and the third factor was teachers' perceived autonomy, and support from schools and colleagues. Regression models showed the predictive power of the factors on teachers' intention to implement PBL, with their perceptions of the value of PBL being the strongest predictor. Results also indicate that teachers with PBL experience perceived significantly higher levels of competence and support from peers, and placed a higher level of value and perceived less cost in implementing PBL than teachers who had not implemented PBL. Teachers' formal training in PBL played a significant role in positively influencing their perceptions of competence and the value of PBL, and reduced their perceived cost of implementing PBL. This, in turn, enhanced teachers' intention of practicing PBL. For teachers who had previously taught with PBL, their responses to two open-ended questions in this instrument corresponded with the theoretical framework of this study and triangulated well with the quantitative data. These teachers highly valued PBL and they recognized the challenges associated with its implementation. These teachers

  5. A correlation between low back pain and associated factors: a study involving 772 patients who had undergone general physical examination.

    Science.gov (United States)

    Kwon, Min A; Shim, Woo Seok; Kim, Myung Hee; Gwak, Mi Sook; Hahm, Tae Soo; Kim, Gaab Soo; Kim, Chung Su; Choi, Yoon Ho; Park, Jeong Heon; Cho, Hyun Sung; Kim, Tae Hyeong

    2006-12-01

    Many factors are associated with the development of low back pain. Among them, exercise, obesity, smoking, age, educational level and stress are the most common. This study examined the association of these factors with low back pain. An additional aim was to determine a procedure for preventing low back pain. This study analyzed the responses to a questionnaire sent to 772 individuals who had undergone a medical examination at this hospital in 2003 and excluded the individuals who had shown symptoms or their test results indicated a particular disease. Assuming that there were no variables, individuals who exercised regularly 3-4 times per week would have a lower chance of having low back pain than those who did not exercise regularly. The analysis revealed that individuals with a college degree or higher education have a lower chance of experiencing low back pain than those with only a high school education or even college drop-outs. When the other variables were constant, age, extent of obesity (body mass index), smoking and level of stress were not found to affect the development of low back pain. The level of education was associated with the development of low back pain. However, regular exercise 3-4 times per week or more would be most effective in reducing the incidence and duration of low back pain.

  6. Examining risk factors for hypertension in Ghana: evidence from the Study on Global Ageing and Adult Health.

    Science.gov (United States)

    Tenkorang, Eric Y; Kuuire, Vincent; Luginaah, Isaac; Banchani, Emmanuel

    2017-03-01

    Like most countries in sub-Saharan Africa, hypertension contributes substantially to morbidity and mortality in Ghana, yet nationally representative studies that examine the odds of becoming hypertensive among Ghanaians are conspicuously missing. We aimed to fill this void in the literature. The data used for analysis came from the first wave of the Study on Global Ageing and Adult Health (SAGE), collected in Ghana from January 2007 to December 2008 by the World Health Organization (WHO). A total of 5573 respondents were sampled for the study. Random-effects C-log-log models were employed in examining socio-economic, lifestyle and psychosocial factors on the odds of becoming hypertensive in Ghana. Separate models were run for male and females. Results indicated there were strong significant associations between socio-economic, lifestyle and psychosocial factors on the likelihood of becoming hypertensive, among Ghanaian men and women. Compared with the poorest, Ghanaians from wealthy households were significantly more likely to be hypertensive. Educated women, as compared with the uneducated, were also more likely to be hypertensive. Ghanaians who engaged in vigorous or intensive activities continuously, for at least 10 minutes, were significantly less likely to be hypertensive, compared to those who did not. Happier men had lower odds of becoming hypertensive, and depressed women had increased odds of reporting they were hypertensive.

  7. An Examination of Bullying in Georgia Schools: Demographic and School Climate Factors Associated with Willingness to Intervene in Bullying Situations

    Directory of Open Access Journals (Sweden)

    Lori Goldammer

    2013-08-01

    Full Text Available Introduction: Research dedicated to identification of precursors to cases of aggravated bullying in schools has led to enhanced knowledge of risk factors for both victimization and perpetration. However, characteristics among those who are more likely to intervene in such situations are less understood. The purpose of this study is to examine the associations between demographic characteristics, school climate and psychosocial factors, and willingness to intervene in a bullying situation among middle and high school students in Georgia.Methods: We computed analyses using cross-sectional data from the Georgia Student Health Survey II (GSHS 2006 administered to public school students in grades 6, 8, 10, and 12 (n=175,311. We used logistic regression analyses to determine the demographic, school climate and psychosocial factors associated with a willingness to intervene in a bullying situation.Results: Students who were white and who were girls were most likely to report willingness to intervene in bullying situations. Several school-climate factors, such as feeling safe at school, liking school, feeling successful at school and perceiving clear rules at school, were associated with willingness to intervene, while youth who reported binge drinking were less willing to intervene.Conclusion: These findings, while preliminary, indicate that girls, students who are white, and students who experience a relatively positive school climate and adaptive psychosocial factors are more likely to report that they would intervene in bullying situations. These findings may guide how bullying is addressed in schools and underscore the importance of safe school climates. [West J Emerg Med. 2013;14(4:324–328.

  8. Factor Structure and Construct Validity of the Eating Disorder Examination-Questionnaire in College Students: Further Support for a Modified Brief Version

    Science.gov (United States)

    Grilo, Carlos M.; Reas, Deborah L.; Hopwood, Christopher J.; Crosby, Ross D.

    2014-01-01

    Objective The Eating Disorder Examination-Questionnaire (EDE-Q) is widely used in research studies across clinical and non-clinical groups. Relatively little is known about psychometric properties of this measure and the available literature has not supported the proposed scale structure. The current study evaluated the factor structure and construct validity of the EDE-Q in a non-clinical study group of young adults. Method Participants were 801 young adults (573 females, 228 males) enrolled at a large public university in the Midwestern United States who completed the EDE-Q and a battery of behavioral and psychological measures. Results Confirmatory factor analysis (CFA) revealed an inadequate fit for the original EDE-Q structure but revealed a good fit for an alternative structure suggested by recent research with predominately overweight/obese samples. CFA supported a modified 7-item, 3-factor structure; the three factors were interpreted as dietary restraint, shape/weight overvaluation, and body dissatisfaction. Factor loadings and item intercepts were invariant across sex and overweight status. The three factors had less redundancy than the original EDE-Q scales and demonstrated improved convergent and discriminant validity in relation to relevant other measures. Discussion These factor-analytic findings, which replicate findings from studies with diverse predominately overweight/obese samples, supported a modified 7-item, 3-factor structure for the EDE-Q with improved psychometric characteristics. The findings provide further empirical support for the distinction between body dissatisfaction and overvaluation and have implications for assessment and research. These findings need to be replicated in samples of persons with eating-disorder psychopathology including those with anorexia nervosa, bulimia nervosa, and allied states. PMID:25346071

  9. A Comprehensive Examination of the Determinants for Food Risk Perception: Focusing on Psychometric Factors, Perceivers' Characteristics, and Media Use.

    Science.gov (United States)

    You, Myoungsoon; Ju, Youngkee

    2017-01-01

    Risk characteristics within a psychometric paradigm have been of major concern in studies of food risk perception. This study compared the influence of psychometric factors, perceivers' characteristics (i.e., risk attitude, trust, and favorability of the country of origin), and that of the news media on the levels of food risk perception. The interaction of news media with the other two factors was also examined. A nationwide survey (n = 1,500) was conducted. The foods under investigation were Chinese processed foods and Japanese seafood imported to South Korea. In both cases, hierarchical multiple regression analyses revealed that psychometric factors had the greatest influence on food risk perception, followed by perceivers' characteristics and media use. In addition, our results showed that the effect of perceived benefit and dread in Chinese food were salient only for those with little media use. The implication of the interaction effect on food risk perception is discussed in terms of accessibility and limited capacity of information processing.

  10. Covariates of cannabis use progression in a representative population sample of adolescents: a prospective examination of vulnerability and risk factors.

    Science.gov (United States)

    Höfler, M; Lieb, R; Perkonigg, A; Schuster, P; Sonntag, H; Wittchen, H U

    1999-11-01

    AIMS/DESIGN: This study reports findings concerning risk factors for first, "repeated" and "regular" use of cannabis in respondents (N = 1228) who were aged 14-17 years at the outset (i.e. at "baseline") as part of a longitudinal prospective community study (EDSP). Risk factors were assessed at baseline or by separate interviews with the respondents' parents. Cumulative life-time cannabis use was the main outcome measure in this study--assessed by information from both the baseline and the follow-up investigation at an average of 19.7 months later. A cumulative logistic regression model was used to estimate associations. Using seven of a total of 25 variables examined, the final model classified 72.1% of respondents correctly. Family history of substance use disorders, self-esteem and competence, unconditional commitment to not using drugs, immediate availability of drugs, peer group drug use and previous history of nicotine dependence and alcohol use disorders all contributed significantly to the final model, predicting the progression to cannabis use from "no use", to "one time only", "repeated use", and "regular use". In addition to well-documented risk factors such as peer group pressure, availability, low self-esteem and competence, findings suggest that family history and prior experiences with legal drugs play a significant role in the early development of cannabis consumption in teenagers.

  11. Examination of the mass media process and personal factors affecting the assessment of mass media-disseminated health information.

    Science.gov (United States)

    Avcı, Kadriye; Çakır, Tülin; Avşar, Zakir; Üzel Taş, Hanife

    2015-06-01

    This study examined the mass media and personal characteristics leading to health communication inequality as well as the role of certain factors in health communication's mass media process. Using both sociodemographic variables and Maletzke's model as a basis, we investigated the relationship between selected components of the mass communication process, the receiving of reliable health information as a result of health communication, and the condition of its use. The study involved 1853 people in Turkey and was structured in two parts. The first part dealt with questions regarding sociodemographic characteristics, the use of the mass media and the public's ability to obtain health information from it, the public's perception of the trustworthiness of health information, and the state of translating this information into health-promoting behaviours. In the second part, questions related to the mass communication process were posed using a five-point Likert scale. This section tried to establish structural equation modelling using the judgements prepared on the basis of the mass media model. Through this study, it has been observed that sociodemographic factors such as education and age affect individuals' use of and access to communication channels; individuals' trust in and selection of health information from the programme content and their changing health behaviours (as a result of the health information) are related to both their perception of the mass communication process and to sociodemographic factors, but are more strongly related to the former.

  12. batman Interacts with polycomb and trithorax group genes and encodes a BTB/POZ protein that is included in a complex containing GAGA factor.

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    Faucheux, M; Roignant, J-Y; Netter, S; Charollais, J; Antoniewski, C; Théodore, L

    2003-02-01

    Polycomb and trithorax group genes maintain the appropriate repressed or activated state of homeotic gene expression throughout Drosophila melanogaster development. We have previously identified the batman gene as a Polycomb group candidate since its function is necessary for the repression of Sex combs reduced. However, our present genetic analysis indicates functions of batman in both activation and repression of homeotic genes. The 127-amino-acid Batman protein is almost reduced to a BTB/POZ domain, an evolutionary conserved protein-protein interaction domain found in a large protein family. We show that this domain is involved in the interaction between Batman and the DNA binding GAGA factor encoded by the Trithorax-like gene. The GAGA factor and Batman codistribute on polytene chromosomes, coimmunoprecipitate from nuclear embryonic and larval extracts, and interact in the yeast two-hybrid assay. Batman, together with the GAGA factor, binds to MHS-70, a 70-bp fragment of the bithoraxoid Polycomb response element. This binding, like that of the GAGA factor, requires the presence of d(GA)n sequences. Together, our results suggest that batman belongs to a subset of the Polycomb/trithorax group of genes that includes Trithorax-like, whose products are involved in both activation and repression of homeotic genes.

  13. Factors influencing voluntary premarital medical examination in Zhejiang province, China: a culturally-tailored health behavioral model analysis

    Science.gov (United States)

    2014-01-01

    Background Premarital medical examination (PME) compliance rate has dropped drastically since it became voluntary in China in 2003. This study aimed to establish a prediction model to be a theoretic framework for analyzing factors affecting PME compliance in Zhejiang province, China. Methods A culturally-tailored health behavioral model combining the Health Behavioral Model (HBM) and the Theory of Reasoned Action (TRA) was established to analyze the data from a cross-sectional questionnaire survey (n = 2,572) using the intercept method at the county marriage registration office in 12 counties from Zhejiang in 2010. Participants were grouped by high (n = 1,795) and low (n = 777) social desirability responding tendency (SDRT) by Marlowe-Crowne Social Desirability Scale (MCSDS). A structural equation modeling (SEM) was conducted to evaluate behavioral determinants for their influences on PME compliance in both high and low SDRT groups. Results 69.8% of the participants had high SDRT and tended to overly report benefits and underreport barriers, which may affect prediction accuracy on PME participation. In the low SDRT group, the prediction model showed the most influencing factor on PME compliance was behavioral intention, with standardized structural coefficients (SSCs) being 0.75 (P social environmental factors. The verified prediction model was tested to be an effective theoretic framework for the prediction of factors affecting voluntary PME compliance. It also should be noted that internationally available behavioral theories and models need to be culturally tailored to adapt to particular populations. This study has provided new insights for establishing a theoretical model to understand health behaviors in China. PMID:24972866

  14. Study protocol for a natural experiment in a lower socioeconomic area to examine the health-related effects of refurbishment to parks including built-shade (ShadePlus)

    Science.gov (United States)

    Dobbinson, S J; Veitch, J; Salmon, J; Wakefield, M; Staiger, P K; MacInnis, R J; Simmons, J

    2017-01-01

    Introduction Parks in disadvantaged suburbs often have low quality and few amenities, which is likely to result in them being underutilised for recreation and physical activity. Refurbishment of parks, including shade, walking paths and other amenities, may have broad health-related benefits. Methods and analysis The study design, methods and planned analyses for a natural experiment examining the effects of refurbishments including built-shade added to parks in disadvantaged outer suburbs of Melbourne are described. Three intervention parks and three comparison parks matched for equivalence of park and neighbourhood characteristics were selected. Using mixed methods, the outcomes will be assessed during three consecutive spring–summer periods (T1: 2013–2014; T2: 2014–2015: T3: 2015–2016). Primary outcomes included: observed park use, physical activity and shade use. Self-reported social connectedness, community engagement and psychological well-being were assessed as secondary outcomes. Ethics and dissemination This study was approved by Cancer Council Victoria's Human Research Ethics Committee. Studies such as ShadePlus can improve understanding of the broader effects of park refurbishments (including physical activity levels and sun protection behaviours, as well as social connectedness and psychological well-being). The study findings will be disseminated through established urban planning and parks and recreation networks, peer review publications and conference presentations.

  15. Examining Socio-Cultural and Neighborhood Factors Associated with Trajectories of Mexican-Origin Mothers' Education-Related Involvement.

    Science.gov (United States)

    Bhargava, Sakshi; Bámaca-Colbert, Mayra Y; Witherspoon, Dawn P; Pomerantz, Eva M; Robins, Richard W

    2017-01-03

    Parental involvement in education is an important determinant of youth's academic success. Yet, there is limited knowledge on how Latino parents' education-related involvement changes over time. Using data from a longitudinal study of 674 Mexican-origin families (mother-adolescent dyad; M age of child at Wave 1=10.4, SD = 0.60), we examined trajectories of parental involvement from 5(th) to 11(th) grade and the effects of socio-cultural (e.g., family SES and acculturation) and contextual (e.g., neighborhood) factors on these trajectories. Results showed that mothers reduced two aspects of the educational involvement: home-based involvement and academic aspirations, but increased on a third aspect of involvement, resource seeking. Furthermore, family SES, acculturation, and neighborhood context were differentially associated with mothers' involvement at 5(th) grade and predicted changes in involvement across elementary and high school.

  16. International note: what factors are associated with reading, mathematics, and science literacy of Indian adolescents? A multilevel examination.

    Science.gov (United States)

    Areepattamannil, Shaljan

    2014-06-01

    A sample of 15-year-olds in India took part in the Program for International Student Assessment (PISA) for the first time in 2010. The PISA reading, mathematics, and science literacy scores of Indian adolescents were considerably lower than their counterparts in most PISA participating countries. In order to explore potential reasons for this, the present study, therefore, drawing on data from the fourth cycle of PISA and employing multilevel modeling, examined the relations of student- and school-level factors to reading, mathematics, and science literacy among 4826 15-year-old students from 213 schools in India. Gender, metacognitive learning strategies, students' positive attitudes toward school, and students' positive perceptions of classroom climate were found to be significantly associated with Indian adolescents' performance on the PISA assessment.

  17. Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography

    Science.gov (United States)

    Kim, Hye-Geum; Kong, Eun-Jung; Cheon, Eun-Jin; Kim, Hae-Won; Koo, Bon-Hoon

    2016-01-01

    The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory. PMID:27776391

  18. Development of multidrug resistance due to multiple factors including P-glycoprotein overexpression under K-selection after MYC and HRAS oncogene activation.

    Science.gov (United States)

    Nakamura, Yukari; Sato, Hiroyuki; Motokura, Toru

    2006-05-15

    Multistep tumorigenesis is a form of microevolution consisting of mutation and selection. To clarify the role of selection modalities in tumor development, we examined two alternative evolutionary conditions, r-selection in sparse culture, which allows cells to proliferate rapidly, and K-selection in confluent culture, in which overcrowding constrains cell proliferation. Using MYC- and EJ-RAS-transformed rat embryo fibroblasts, we found that K-selected cells acquired and stably maintained multidrug resistance (MDR) to DOX, VCR, MTX and Ara-C. Then, we examined the involvement of a number of factors potentially causal of the development of MDR, that is, ploidy, Tp53 mutation, doubling time and the expression levels of genes related to drug resistance. Although ploidy status and Tp53 mutations did not correlate with MDR, we found that Abcb1/Mdr1, encoding P-glycoprotein (Pgp), was significantly upregulated after K-selection. Cyclosporin A, a competitive inhibitor of Pgp, increased the intracellular accumulation of DOX and reduced the resistance to it. Indeed, the population of Pgp-transfected cells significantly expanded under K-, but not under r-selection. In addition to Pgp upregulation, altered expression of other genes such as Cda/cytidine deaminase and Slc29a1/equilibrative nucleoside transporter 1 and prolonged doubling times were associated with MDR. This system reproduces events associated with MDR in vivo and would be useful for analysis of MDR development.

  19. Assessment of Factors Associated with Breast Self-Examination among Health Extension Workers in West Gojjam Zone, Northwest Ethiopia

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    Muluken Azage

    2013-01-01

    Full Text Available Background. Early detection of breast cancer using breast self-examination (BSE plays an important role in decreasing its morbidity and mortality. Objective. To identify factors associated with BSE among health extension workers in Northwest Ethiopia. Methods. Cross-sectional study design was employed from October to November, 2012 in West Gojjam Zone of Amhara region. Simple random sampling technique was used to recruit a total of 390 health extension workers (HEWs. A structured Amharic questionnaire was used to collect the data. Data were entered and analyzed using SPSS statistical package version 16.0. Result. This study found that 37% of HEWs had ever practiced BSE and 14.4% practiced it regularly. The three main reasons for not doing regular BSE were no breast problem (53.2%, not knowing the technique of BSE (30.6%, and not knowing the importance of BSE (21.4%. Discussion with families on BSE and history of breast examination by health professionals were found significantly associated with ever practice of BSE. Conclusion. BSE practice was found low in this study. Having information on the importance of BSE was predictor of BSE practice. Therefore, it is important to give training on BSE techniques and its role on breast cancer prevention for HEWs.

  20. Assessment of Factors Associated with Breast Self-Examination among Health Extension Workers in West Gojjam Zone, Northwest Ethiopia.

    Science.gov (United States)

    Azage, Muluken; Abeje, Gedefaw; Mekonnen, Alemtsehay

    2013-01-01

    Background. Early detection of breast cancer using breast self-examination (BSE) plays an important role in decreasing its morbidity and mortality. Objective. To identify factors associated with BSE among health extension workers in Northwest Ethiopia. Methods. Cross-sectional study design was employed from October to November, 2012 in West Gojjam Zone of Amhara region. Simple random sampling technique was used to recruit a total of 390 health extension workers (HEWs). A structured Amharic questionnaire was used to collect the data. Data were entered and analyzed using SPSS statistical package version 16.0. Result. This study found that 37% of HEWs had ever practiced BSE and 14.4% practiced it regularly. The three main reasons for not doing regular BSE were no breast problem (53.2%), not knowing the technique of BSE (30.6%), and not knowing the importance of BSE (21.4%). Discussion with families on BSE and history of breast examination by health professionals were found significantly associated with ever practice of BSE. Conclusion. BSE practice was found low in this study. Having information on the importance of BSE was predictor of BSE practice. Therefore, it is important to give training on BSE techniques and its role on breast cancer prevention for HEWs.

  1. Intimate partner violence perpetrated by young adult women against men in Ukraine: Examining individual, familial, and cultural factors.

    Science.gov (United States)

    Balabukha, Iryna; Krishnakumar, Ambika; Narine, Lutchmie

    2016-07-01

    We examined the role of financial strain, parent-to-parent violence, parent-to-child violence, emotional distress, and alcohol use in intimate partner violence perpetrated by young adult women against men in Ukraine. The moderating role of acceptability of intimate partner violence and violence-related laws and regulations was also examined. Four hundred and six full-time female university students from four universities in Ukraine participated in the study. We found that emotional distress, parent-to-parent, and parent-to-child violence mediated the link between financial strain and intimate partner violence perpetrated by women on men. However, we found limited support for the moderating role of acceptability of intimate partner violence and violence-related laws and regulations in the relationship between individual and familial factors on intimate partner violence. The findings from this investigation suggest that there is a distinct need for supporting families and individuals in dealing with issues of intimate partner violence directed by women against men in Ukraine. Aggr. Behav. 42:380-393, 2016. © 2015 Wiley Periodicals, Inc.

  2. Examining the prevalence rate of Pediculus capitis infestation according to sex and social factors in primary school children

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    Abbas Doroodgar

    2014-02-01

    Full Text Available Objective: To determine the prevalence rate of head louse infestation among elementary students, and examine the associated factors with infection in the city of Aran and Bidgol. Methods: A total of 19 boys’ and girls’ primary schools were selected by multistage, systematic random sampling. Overall, 3 590 students were examined for head lice infestation in urban areas of Aran and Bidgol during 2008. The diagnosis was based on live louse or nit on the scalp of students. The students were screened by standard questionnaire and demographic data in addition to related information were obtained by interview and observation. The data were analyzed by SPSS software using chi-square and Fisher’s exact tests. Results: The mean age of students was (8.68依1.58 years ranging between 6-12 years. The total prevalence of head louse infestation was 0.47%. This rate was 0.42% and 0.05% in female and male, respectively. There was a significant association between pediculosis and sex, father’s job, mother’s education, access to bathroom in home, prior infection, drug use and nationality, respectively (P<0.05. Conclusions: The results showed that pediculosis was not a major health priority among primary school in city of Aran and Bidgol. However, enhancing the knowledge of students about head lice infestation and the existence of health teachers in schools can play a significant role in disease control.

  3. Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors?

    Science.gov (United States)

    Alswaidi, F M; O'Brien, S J

    2010-11-01

    In January 2008, the Saudi Arabian health authority included mandatory testing for HIV, HBV and HCV viruses in the premarital screening program. Epidemiologically, there were few justifications for their inclusion as disease prevalences and distributions are poorly understood in the population. This study aims to provide information about HBV, HCV and HIV prevalences and risk factors for disease transmission and so produce evidence for informed decision-making on the inclusion of these infectious diseases in the screening program. This is a cross-sectional descriptive study embedded in the existing national premarital screening program for thalassaemia and sickle cell disease to estimate the prevalence of HIV, HBV and HCV infections (n=74,662 individuals), followed by a case-control study to identify risk factors responsible for infection transmission (n=540). The average HIV prevalence is 0.03%, 1.31% for HBV and 0.33% for HCV. Sharing personal belongings particularly razors, blood transfusions, cuts at barbershops and extramarital relationships showed the highest significant associations with the transmission of these viruses. The prevalences of HIV, HBV and HCV in Saudi Arabia are among the lowest worldwide. However, all the important risk factors associated with transmitting these viruses are significantly present in the Saudi community. Saudi Arabia is financially capable of screening for these infections in the mandatory premarital program and of providing medical care for the discovered cases, but focusing on the health education programs may offset the need to mandatory testing.

  4. Evaluation of the spatial patterns and risk factors, including backyard pigs, for classical swine fever occurrence in Bulgaria using a Bayesian model

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    Beatriz Martínez-López

    2014-05-01

    Full Text Available The spatial pattern and epidemiology of backyard pig farming and other low bio-security pig production systems and their role in the occurrence of classical swine fever (CSF is described and evaluated. A spatial Bayesian model was used to explore the risk factors, including human demographics, socioeconomic and environmental factors. The analyses were performed for Bulgaria, which has a large number of backyard farms (96% of all pig farms in the country are classified as backyard farms, and it is one of the countries for which both backyard pig and farm counts were available. Results reveal that the high-risk areas are typically concentrated in areas with small family farms, high numbers of outgoing pig shipments and low levels of personal consumption (i.e. economically deprived areas. Identification of risk factors and high-risk areas for CSF will allow to targeting risk-based surveillance strategies leading to prevention, control and, ultimately, elimination of the disease in Bulgaria and other countries with similar socio-epidemiological conditions.

  5. Factors influencing the adoption of an innovation: An examination of the uptake of the Canadian Heart Health Kit (HHK

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    Plotnikoff Ronald C

    2008-10-01

    Full Text Available Abstract Background There is an emerging knowledge base on the effectiveness of strategies to close the knowledge-practice gap. However, less is known about how attributes of an innovation and other contextual and situational factors facilitate and impede an innovation's adoption. The Healthy Heart Kit (HHK is a risk management and patient education resource for the prevention of cardiovascular disease (CVD and promotion of cardiovascular health. Although previous studies have demonstrated the HHK's content validity and practical utility, no published study has examined physicians' uptake of the HHK and factors that shape its adoption. Objectives Conceptually informed by Rogers' Diffusion of Innovation theory, and Theory of Planned Behaviour, this study had two objectives: (1 to determine if specific attributes of the HHK as well as contextual and situational factors are associated with physicians' intention and actual usage of the HHK kit; and (2, to determine if any contextual and situational factors are associated with individual or environmental barriers that prevent the uptake of the HHK among those physicians who do not plan to use the kit. Methods A sample of 153 physicians who responded to an invitation letter sent to all family physicians in the province of Alberta, Canada were recruited for the study. Participating physicians were sent a HHK, and two months later a study questionnaire assessed primary factors on the physicians' clinical practice, attributes of the HHK (relative advantage, compatibility, complexity, trialability, observability, confidence and control using the HHK, barriers to use, and individual attributes. All measures were used in path analysis, employing a causal model based on Rogers' Diffusion of Innovations Theory and Theory of Planned Behaviour. Results 115 physicians (follow up rate of 75% completed the questionnaire. Use of the HHK was associated with intention to use the HHK, relative advantage, and years of

  6. An Examination of Emotion Regulation and Alcohol Use as Risk Factors for Female-Perpetrated Dating Violence.

    Science.gov (United States)

    Ortiz, Edwin; Shorey, Ryan C; Cornelius, Tara L

    2015-01-01

    Dating violence is a serious problem among college students. Research indicates that females perpetrate as much, if not more, psychological and physical aggression against their dating partners relative to their male counterparts. Unfortunately, there is considerably less research on risk factors for female-perpetrated dating violence, hindering efforts aimed at preventing violence in their relationships. This study examined 2 risk factors for female-perpetrated dating violence, namely alcohol use and emotion regulation, within a sample of undergraduate female college students (N = 379). Using structural equation modeling, results demonstrated that emotion regulation was associated with psychological aggression perpetration, and this was partially mediated by alcohol use. Moreover, a 2-chain mediation was present, such that emotion regulation deficits predicted alcohol use, which in turn predicted psychological aggression, which finally predicted physical aggression. These findings are consistent with theoretical models of dating violence and indicate that intervention programs should focus their efforts on increasing adaptive emotion regulation, decreasing alcohol use, and reducing psychological aggression.

  7. Type 2 diabetes mellitus unawareness, prevalence, trends and risk factors: National Health and Nutrition Examination Survey (NHANES) 1999-2010.

    Science.gov (United States)

    Zhang, Nana; Yang, Xin; Zhu, Xiaolin; Zhao, Bin; Huang, Tianyi; Ji, Qiuhe

    2017-04-01

    Objectives To determine whether the associations with key risk factors in patients with diagnosed and undiagnosed type 2 diabetes mellitus (T2DM) are different using data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2010. Methods The study analysed the prevalence and association with risk factors of undiagnosed and diagnosed T2DM using a regression model and a multinomial logistic regression model. Data from the NHANES 1999-2010 were used for the analyses. Results The study analysed data from 10 570 individuals. The overall prevalence of diagnosed and undiagnosed T2DM increased significantly from 1999 to 2010. The prevalence of undiagnosed T2DM was significantly higher in non-Hispanic whites, in individuals levels compared with diagnosed T2DM. Body mass index, low economic status or low educational level had no effect on T2DM diagnosis rates. Though diagnosed T2DM was associated with favourable diet/carbohydrate intake behavioural changes, it had no effect on physical activity levels. Conclusion The overall T2DM prevalence increased between 1999 and 2010, particularly for undiagnosed T2DM in patients that were formerly classified as low risk.

  8. An Examination Some of Educational – Extension Factors Influencing Use of Transgenic Plants (Case Study: Ilam, Iran

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    Mohammad Bagher Arayesh

    2015-12-01

    Full Text Available The purpose of this study was to examine the effect of educational – extension factors on the use of transgenic plants. This study was conducted through a survey design. The research was an applied study type. The research method of this study is descriptive-correlation. Statistical population of the study consisted of all of biotechnology experts of Research Center of Agriculture of Ilam Province (N=63. Census method was used in this study. A questionnaire was the main tool which the face and content its validity was confirmed by panel of University Experts. Reliability Coefficient (Cronbach's alpha of the questionnaire was 92%. Results showed that the use of media (radio and TV was the most important factor in the use of transgenic plants. The result of Spearman correlation coefficients showed that, there was a significant relationship between the variables such as the use of communication media, communication with extension professionals, and scientific rank of professional with use of transgenic plants. Multiple regression analysis results showed that varriables like scientific rank, relationship with extension professionals and mass media have positive effect on the dependent variable of application of transgenic plants, describing 53.2% of the changes of the mentioned dependent variable.

  9. A STUDY OF CHINESE YUAN (RMB APPRECIATION ACCOMPANYING WITH OTHERS FACTORS INCLUDING FOREIGN DIRECT INVESTMENT (FDI AND THEIR EFFECT ON CHINA ECONOMY

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    Ping-fu (Brian LAI

    2014-07-01

    Full Text Available The Chinese Yuan (RMB has been on the trend of appreciation over the last decade, and such a trend will likely be continuing for some years over the next decade. According to some scholars in their published literatures, the appreciation of RMB, the influx of Foreign Direct Investment (FDI has been ongoing accompanying the sustained growing economy in mainland China over the past decade. It is believed that the China economy has an implication from some significant factors including appreciation of RMB, interest rate of RMB, inflation and continuous increase of FDI for the next several years. The present study aims to provide an emphasis on investigation into effect on China economy as a result of appreciation of RMB and FDI together with some other factors, and to provide an outlook on the economy in China for the coming decades. First, a review was carried on relevant background information and development history of RMB and FDI. There are many reasons and factors behind leading to the sustained growth in the economy in China in the last decade and such effects were in coverage in the literature review. An overview of the development of RMB exchange mechanism, and other variables including (1 RMB exchange rate, (2 China interest rate, (3 Foreign Direct Investment (FDI, (4 Trade Balance of China, (5 Annual Inflation rate in China, (6 Energy Consumption in China, (7 Foreign Exchange Reserve in China, (8 China wages, (9 China External Debt and (10 China Consumer Price Index, which may have effect on the growth of the economy in China is covered in the literature review conducted in Chapter 2.

  10. The incidence of hypertension and its risk factors in the German adult population: results from the German National Health Interview and Examination Survey 1998 and the German Health Interview and Examination Survey for Adults 2008-2011.

    Science.gov (United States)

    Diederichs, Claudia; Neuhauser, Hannelore

    2017-02-01

    To analyze incident hypertension and its risk factors based on 11.9 years follow-up of a recent National Examination Survey cohort in Germany. Out of 7124 participants of the German National Health Interview and Examination Survey 1998 (GNHIES98), 640 had died at follow-up 2008-2011 and 3045 were reexamined as part of the German Health Interview and Examination Survey for Adults 2008-2011 (DEGS1). Baseline and follow-up included standardized blood pressure (BP) measurements. Hypertension was defined as BP of at least 140/90 mmHg or intake of antihypertensive medication in participants with known hypertension. Out of 2231 GNHIES98-DEGS1 participants aged 18-79 years without hypertension in 1998, 26.2% developed hypertension within a mean of 11.9 (range 10.0-14.1) years (men 29.0%, women 23.4%). In univariate analysis, hypertension incidence was positively associated with age, BMI, initial BP levels, pulse pressure, and alcohol consumption. Comorbidities such as diabetes and hyperlipidemia increased the chance to develop hypertension. In the multivariate model, initial SBP and DBP levels had the strongest influence on the development of future hypertension (7% increase in men and 5% in women per mmHg SBP). The percentage of aware, treated, and controlled hypertensive patients were 75.8, 62.1, and 50.3% in men and 83.8, 73.3, and 59.0% in women. The high 11.9-year incidence in all age groups points to the lifelong potential for prevention of hypertension.

  11. Prevalence and Risk Factors of Self-Reported Smell and Taste Alterations: Results from the 2011–2012 US National Health and Nutrition Examination Survey (NHANES)

    Science.gov (United States)

    Rawal, Shristi; Hoffman, Howard J.; Bainbridge, Kathleen E.; Huedo-Medina, Tania B.

    2016-01-01

    Chemosensory problems challenge health through diminished ability to detect warning odors, consume a healthy diet, and maintain quality of life. We examined the prevalence and associated risk factors of self-reported chemosensory alterations in 3603 community-dwelling adults (aged 40+ years), from the nationally representative, US National Health and Nutrition Examination Survey (NHANES) 2011–2012. In this new NHANES component, technicians surveyed adults in the home about perceived smell and taste problems, distortions, and diminished abilities since age 25 (termed “alterations”), and chemosensory-related health risks and behaviors. The prevalence of self-reported smell alteration was 23%, including phantosmia at 6%; taste was 19%, including dysgeusia at 5%. Prevalence rates increased progressively with age, highest in those aged 80+ years (smell, 32%; taste, 27%). In multivariable logistic regression, controlling for sociodemographics, health behaviors, and chemosensory-related conditions, the strongest independent risk factor for smell alteration was sinonasal symptoms (odds ratio [OR] = 2.06; 95% confidence interval [CI]: 1.63–2.61), followed by heavy drinking, loss of consciousness from head injury, family income ≤110% poverty threshold, and xerostomia. For taste, the strongest risk factor was xerostomia (OR = 2.65; 95% CI: 1.97–3.56), followed by nose/facial injury, lower educational attainment, and fair/poor health. Self-reported chemosensory alterations are prevalent in US adults, supporting increased attention to decreasing their modifiable risks, managing safety/health consequences, and expanding chemosensory screening/testing and treatments. PMID:26487703

  12. Prevalence and Risk Factors of Self-Reported Smell and Taste Alterations: Results from the 2011-2012 US National Health and Nutrition Examination Survey (NHANES).

    Science.gov (United States)

    Rawal, Shristi; Hoffman, Howard J; Bainbridge, Kathleen E; Huedo-Medina, Tania B; Duffy, Valerie B

    2016-01-01

    Chemosensory problems challenge health through diminished ability to detect warning odors, consume a healthy diet, and maintain quality of life. We examined the prevalence and associated risk factors of self-reported chemosensory alterations in 3603 community-dwelling adults (aged 40+ years), from the nationally representative, US National Health and Nutrition Examination Survey (NHANES) 2011-2012. In this new NHANES component, technicians surveyed adults in the home about perceived smell and taste problems, distortions, and diminished abilities since age 25 (termed "alterations"), and chemosensory-related health risks and behaviors. The prevalence of self-reported smell alteration was 23%, including phantosmia at 6%; taste was 19%, including dysgeusia at 5%. Prevalence rates increased progressively with age, highest in those aged 80+ years (smell, 32%; taste, 27%). In multivariable logistic regression, controlling for sociodemographics, health behaviors, and chemosensory-related conditions, the strongest independent risk factor for smell alteration was sinonasal symptoms (odds ratio [OR] = 2.06; 95% confidence interval [CI]: 1.63-2.61), followed by heavy drinking, loss of consciousness from head injury, family income ≤110% poverty threshold, and xerostomia. For taste, the strongest risk factor was xerostomia (OR = 2.65; 95% CI: 1.97-3.56), followed by nose/facial injury, lower educational attainment, and fair/poor health. Self-reported chemosensory alterations are prevalent in US adults, supporting increased attention to decreasing their modifiable risks, managing safety/health consequences, and expanding chemosensory screening/testing and treatments. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Factors associated with negative direct sputum examination in Asian and African HIV-infected patients with tuberculosis (ANRS 1260.

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    Loïc Chartier

    Full Text Available OBJECTIVE: To identify factors associated with negative direct sputum examination among African and Cambodian patients co-infected by Mycobacterium tuberculosis and HIV. DESIGN: Prospective multicenter study (ANRS1260 conducted in Cambodia, Senegal and Central African Republic. METHODS: Univariate and multivariate analyses (logistic regression were used to identify clinical and radiological features associated with negative direct sputum examination in HIV-infected patients with positive M. tuberculosis culture on Lowenstein-Jensen medium. RESULTS: Between September 2002 and December 2005, 175 co-infected patients were hospitalized with at least one respiratory symptom and pulmonary radiographic anomaly. Acid-fast bacillus (AFB examination was positive in sputum samples from 110 subjects (63% and negative in 65 patients (37%. Most patients were at an advanced stage of HIV disease (92% at stage III or IV of the WHO classification with a median CD4 cell count of 36/mm³. In this context, we found that sputum AFB negativity was more frequent in co-infected subjects with associated respiratory tract infections (OR = 2.8 [95%CI:1.1-7.0], dyspnea (OR = 2.5 [95%CI:1.1-5.6], and localized interstitial opacities (OR = 3.1 [95%CI:1.3-7.6], but was less frequent with CD4 ≤ 50/mm³ (OR = 0.4 [95%CI:0.2-0.90, adenopathies (OR = 0.4 [95%CI:0.2-0.93] and cavitation (OR = 0.1 [95%CI:0.03-0.6]. CONCLUSIONS: One novel finding of this study is the association between concomitant respiratory tract infection and negative sputum AFB, particularly in Cambodia. This finding suggests that repeating AFB testing in AFB-negative patients should be conducted when broad spectrum antibiotic treatment does not lead to complete recovery from respiratory symptoms. In HIV-infected patients with a CD4 cell count below 50/mm3 without an identified cause of pneumonia, systematic AFB direct sputum examination is justified because of atypical clinical

  14. Factors associated with negative direct sputum examination in Asian and African HIV-infected patients with tuberculosis (ANRS 1260).

    Science.gov (United States)

    Chartier, Loïc; Leng, Chanthy; Sire, Jean-Marie; Le Minor, Odile; Saman, Manil; Bercion, Raymond; Rahalison, Lila; Fontanet, Arnaud; Germany, Yves; L'her, Pierre; Mayaud, Charles; Vray, Muriel

    2011-01-01

    To identify factors associated with negative direct sputum examination among African and Cambodian patients co-infected by Mycobacterium tuberculosis and HIV. Prospective multicenter study (ANRS1260) conducted in Cambodia, Senegal and Central African Republic. Univariate and multivariate analyses (logistic regression) were used to identify clinical and radiological features associated with negative direct sputum examination in HIV-infected patients with positive M. tuberculosis culture on Lowenstein-Jensen medium. Between September 2002 and December 2005, 175 co-infected patients were hospitalized with at least one respiratory symptom and pulmonary radiographic anomaly. Acid-fast bacillus (AFB) examination was positive in sputum samples from 110 subjects (63%) and negative in 65 patients (37%). Most patients were at an advanced stage of HIV disease (92% at stage III or IV of the WHO classification) with a median CD4 cell count of 36/mm³. In this context, we found that sputum AFB negativity was more frequent in co-infected subjects with associated respiratory tract infections (OR = 2.8 [95%CI:1.1-7.0]), dyspnea (OR = 2.5 [95%CI:1.1-5.6]), and localized interstitial opacities (OR = 3.1 [95%CI:1.3-7.6]), but was less frequent with CD4 ≤ 50/mm³ (OR = 0.4 [95%CI:0.2-0.90), adenopathies (OR = 0.4 [95%CI:0.2-0.93]) and cavitation (OR = 0.1 [95%CI:0.03-0.6]). One novel finding of this study is the association between concomitant respiratory tract infection and negative sputum AFB, particularly in Cambodia. This finding suggests that repeating AFB testing in AFB-negative patients should be conducted when broad spectrum antibiotic treatment does not lead to complete recovery from respiratory symptoms. In HIV-infected patients with a CD4 cell count below 50/mm3 without an identified cause of pneumonia, systematic AFB direct sputum examination is justified because of atypical clinical features (without cavitation) and high pulmonary mycobacterial

  15. Association between reproductive factors and age-related macular degeneration in postmenopausal women: the Korea National Health and Nutrition Examination Survey 2010-2012.

    Directory of Open Access Journals (Sweden)

    Bum-Joo Cho

    Full Text Available PURPOSE: To examine the association between female reproductive factors and age-related macular degeneration (AMD in postmenopausal women. DESIGN: Nationwide population-based cross-sectional study. METHODS: A nationally representative dataset acquired from the 2010-2012 Korea National Health and Nutrition Examination Survey was analyzed. The dataset involved information for 4,377 postmenopausal women aged ≥50 years with a fundus photograph evaluable for AMD in either eye. All participants were interviewed using standardized questionnaires to determine reproductive factors including menstruation, pregnancy, parity, lactation, and hormonal use. The association between reproductive factors and each type of AMD was investigated. RESULTS: The mean age of the study participants was 63.1±0.2 years. Mean ages at menarche and menopause were 16.1±0.0 and 49.2±0.1 years, respectively. The overall prevalence rates of early and late AMD were 11.2% (95% confidence interval [CI], 10.1-12.5 and 0.8% (95% CI, 0.5-1.2, respectively. When adjusted for age, neither smoking nor alcohol use was associated with the presence of any AMD or late AMD. Multivariate logistic regression analysis revealed age (OR, 1.12 per 1 year, duration of lactation (OR, 0.91 per 6 months, and duration of use of oral contraceptive pills (OCP (OR, 1.10 per 6 months as associated factors for late AMD. The other variables did not yield a significant correlation with the risk of any AMD or late AMD. CONCLUSION: After controlling for confounders, a longer duration of lactation appeared to protect against the development of late AMD. A longer duration of OCP use was associated with a higher risk of late AMD.

  16. Prevalence study and risk factor analysis of selected bacterial, protozoal and viral, including vector-borne, pathogens in cats from Cyprus.

    Science.gov (United States)

    Attipa, Charalampos; Papasouliotis, Kostas; Solano-Gallego, Laia; Baneth, Gad; Nachum-Biala, Yaarit; Sarvani, Elpida; Knowles, Toby G; Mengi, Sena; Morris, David; Helps, Chris; Tasker, Séverine

    2017-03-13

    Feline infectious agent studies are lacking in Cyprus. The aims of this study were to determine the prevalence and risk factors for various feline infectious agents, including feline vector-borne pathogens (FVBP), in cats from Cyprus. A cross-sectional, descriptive, multicentre study was performed on 174 feline samples [138 owned and 36 shelter-feral, including both healthy (43) and non-healthy (131), cats] from private veterinary clinics from all six districts of Cyprus. Real-time quantitative polymerase chain reaction (qPCR) assays were used to detect Mycoplasma haemofelis (Mhf), "Candidatus Mycoplasma haemominutum" (CMhm) and "Candidatus Mycoplasma turicensis" (CMt). The population was tested for four FVBP including Bartonella henselae and Leishmania spp. using qPCR, while conventional PCR assays were used to detect Ehrlichia/Anaplasma spp. and Hepatozoon spp. Serological assays were performed to detect Leishmania infantum antibodies, feline leukaemia virus (FeLV) antigen and feline immunodeficiency virus (FIV) antibodies. Statistical analysis was performed to test associations and possible risk factors between variables and infectious agents. Ninety-six (55.2%) of the 174 cats were PCR-positive for at least one infectious agent. Forty-six cats (26.4%) were haemoplasma positive, including 13 (7.5%) for Mhf, 36 (20.7%) for CMhm and 12 (6.9%) for CMt. Sixty-six cats (37.9%) were positive for Hepatozoon spp., while 19 (10.9%) were positive for B. henselae, four (2.3%) for Leishmania spp. and one (0.6%) for Ehrlichia/Anaplasma spp. Sequencing revealed the presence of Hepatozoon felis, L. infantum and Anaplasma platys. Of the 164 cats that underwent retroviral serology, 10 (6.1%) were FeLV-positive and 31 (18.9%) were FIV-positive, while L. infantum serology was positive in 7 (4.4%) of the 160 cats tested. Multivariable logistic regression revealed significant associations for various infectious agents including L. infantum with each of Hepatozoon spp. and CMt

  17. Self-Directed Violence Aboard U.S. Navy Aircraft Carriers: An Examination of General and Shipboard-Specific Risk and Protective Factors.

    Science.gov (United States)

    Saitzyk, Arlene; Vorm, Eric

    2016-04-01

    Self-directed violence (SDV), which includes suicidal ideation with and without intent, suicidal preparatory behaviors and attempts with and without harm, non-suicidal self-directed violence, and completed suicide, has been a rising concern in the military. Military shipboard personnel may represent a unique subset of this population due to the distinct nature of deployment stressors and embedded supports. As such, one might expect differences in the prevalence of SDV between this group and other active duty personnel, signifying a distinct operational impact. This study analyzed the prevalence of SDV among personnel assigned or deployed to U.S. Navy aircraft carriers, and examined whether occurrences varied by descriptors commonly identified in the literature (e.g., age, gender, marital status, pay grade/rank). This study also examined characteristics specific to life aboard a U.S. Navy aircraft carrier in order to better understand the issues particular to this population. Descriptive analyses and relative risk findings suggested similarities in demographic risk factors to the general military population, but also striking differences related to occupational specialty and assigned department. This study is the first to shed light on risk and protective factors relevant to shipboard personnel.

  18. Utilizing interview and self-report assessment of the Five-Factor Model to examine convergence with the alternative model for personality disorders.

    Science.gov (United States)

    Helle, Ashley C; Trull, Timothy J; Widiger, Thomas A; Mullins-Sweatt, Stephanie N

    2017-07-01

    An alternative model for personality disorders is included in Section III (Emerging Models and Measures) of Diagnostic and Statistical Manual of Mental Disorders, (5th ed.; DSM-5). The DSM-5 dimensional trait model is an extension of the Five-Factor Model (FFM; American Psychiatric Association, 2013). The Personality Inventory for DSM-5 (PID-5) assesses the 5 domains and 25 traits in the alternative model. The current study expands on recent research to examine the relationship of the PID-5 with an interview measure of the FFM. The Structured Interview for the Five Factor Model of Personality (SIFFM) assesses the 5 bipolar domains and 30 facets of the FFM. Research has indicated that the SIFFM captures maladaptive aspects of personality (as well as adaptive). The SIFFM, NEO PI-R, and PID-5 were administered to participants to examine their respective convergent and discriminant validity. Results provide evidence for the convergence of the 2 models using self-report and interview measures of the FFM. Clinical implications and future directions are discussed, particularly a call for the development of a structured interview for the assessment of the DSM-5 dimensional trait model. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Study on the social maturity, self-perception, and associated factors, including motor coordination, of children with attention deficit hyperactivity disorder.

    Science.gov (United States)

    Kaneko, Fumiko; Okamura, Hitoshi

    2005-01-01

    This study was designed to identify characteristics of social maturity and self-perception in children with attention deficit hyperactivity disorder (ADHD) and to elucidate associated factors, including motor coordination. The subjects were 15 children (14 boys and 1 girl, in elementary school grades 3 to 6). Their characteristics were assessed with the Movement Assessment Battery for Children (M-ABC), the Japanese version of the Social Maturity Scale-R (S-M scale), and Harter's Self Perception Profile for Children (SPPC). The results of the study suggested that most of the subjects had some degree of motor problem and delay of social maturity. They also suggested an association between social maturity and static-dynamic balance, which was one of the indices of motor coordination.

  20. Examination of Factors that Influence the Operation Income and Expenditure Balance Difference Rate of 20 Educational Foundation Universities.

    Science.gov (United States)

    Nakajima, Hisato; Yano, Kouya; Nagasawa, Kaoko; Katou, Satoka; Yokota, Kuninobu

    2017-01-01

    The objective of this study is to examine the factors that influence the operation income and expenditure balance ratio of school corporations running university hospitals by multiple regression analysis. 1. We conducted cluster analysis of the financial ratio and classified the school corporations into those running colleges and universities.2. We conducted multiple regression analysis using the operation income and expenditure balance ratio of the colleges as the variables and the Diagnosis Procedure Combination data as the explaining variables.3. The predictive expression was used for multiple regression analysis. 1. The school corporations were divided into those running universities (7), colleges (20) and others. The medical income ratio and the debt ratio were high and the student payment ratio was low in the colleges.2. The numbers of emergency care hospitalizations, operations, radiation therapies, and ambulance conveyances, and the complexity index had a positive influence on the operation income and expenditure balance ratio. On the other hand, the number of general anesthesia procedures, the cover rate index, and the emergency care index had a negative influence.3. The predictive expression was as follows.Operation income and expenditure balance ratio = 0.027 × number of emergency care hospitalizations + 0.005 × number of operations + 0.019 × number of radiation therapies + 0.007 × number of ambulance conveyances - 0.003 × number of general anesthesia procedures + 648.344 × complexity index - 5877.210 × cover rate index - 2746.415 × emergency care index - 38.647Conclusion: In colleges, the number of emergency care hospitalizations, the number of operations, the number of radiation therapies, and the number of ambulance conveyances and the complexity index were factors for gaining ordinary profit.

  1. Cross-cultural examination of the five-factor model of drinking motives in Spanish and Canadian undergraduates.

    Science.gov (United States)

    Mezquita, Laura; Stewart, Sherry H; Kuntsche, Emmanuel; Grant, Valerie V

    2016-06-14

    This study aims to test the cross-cultural suitability of Modified Drinking Motives Questionnaire-Revised (M DMQ-R) (Grant, Stewart, O'Connor, Blackwell, & Conrod, 2007). The sample included 571 Spanish and 571 Canadian undergraduates between the ages of 18 and 22 (65.8% women). The confirmatory factor analysis demonstrated factorial invariance between samples. The regression analysis showed that social, enhancement and low conformity motives were related to drinking frequency and drinking quantity in the total sample. No moderation effect of country on predicting alcohol consumption was found. The results suggest that M DMQ-R is a suitable instrument for comparing drinking motives across Spanish and Canadian undergraduates, and that motives-focused prevention and treatment programmes developed in one country could be generalised to another.

  2. Risk factors for bloodstream infection caused by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: A focus on antimicrobials including cefepime.

    Science.gov (United States)

    Chopra, Teena; Marchaim, Dror; Johnson, Paul C; Chalana, Indu K; Tamam, Zeinab; Mohammed, Mazin; Alkatib, Shatha; Tansek, Ryan; Chaudhry, Khawar; Zhao, Jing J; Pogue, Jason M; Kaye, Keith S

    2015-07-01

    Extended-spectrum β-lactamase (ESBL)-producing pathogens represent increasing challenges to physicians because of rising prevalence, high mortality, and challenging treatment. Identifying high risks and early appropriate therapy is critical to favorable outcomes. This is a 5-year retrospective case-case-control study performed at the Detroit Medical Center on adult patients with bloodstream infection (BSI) caused by ESBL-producing and non-ESBL-producing Escherichia coli or Klebsiella pneumoniae, each compared with uninfected controls. Data were collected from December 2004-August 2009. Multivariate analysis was performed using logistic regression. Participants included 103 patients with BSI caused by ESBL-producing pathogens and 79 patients with BSI caused by pathogens that did not produce ESBLs. The mean age of patients in the ESBL group was 67 years; of the patients, 51% were men, 77% were black, and 38% (n = 39) died in hospital. The mean age of patients in the non-ESBL group was 58 years; of the patients, 51% were men, 92% were black, and 22% (n = 17) died in hospital. On multivariate analysis, predictors of BSI caused by ESBL-producing pathogens included central venous catheter (odds ratio [OR], 29.4; 95% confidence interval [CI], 3.0-288.3), prior β-lactam-/β-lactamase-inhibitor therapy (OR, 28.1; 95% CI, 1.99-396.5), and prior cefepime therapy (OR, 22.7; 95% CI, 2.7-192.4). The only risk factor for BSI caused by non-ESBL-producing pathogens was urinary catheter insertion (OR, 18.2; 95% CI, 3.3-100.3). Prior antimicrobial therapy, particularly with β-lactam, was the strongest unique risk factor for BSI caused by ESBL-producing E coli or K pneumoniae. Copyright © 2015. Published by Elsevier Inc.

  3. An examination of the factors by gender and race/ethnicity influencing science, mathematics, and engineering undergraduate degree recipients to enroll in graduate study

    Science.gov (United States)

    Lasiewski, Doreen Kovacsofsky

    Lack of growth in the science talent pool raises concerns about the ability of colleges and universities to meet the demands of the nation's labor market for scientists and engineers. Previous research has focused on ways to improve the K--16 learning environment and increase retention rates of undergraduate students in the sciences. This study extends previous work by considering the next stage in the educational pipeline---the transition to graduate study. The purpose of this study is to develop a model of factors related to science, mathematics, and engineering (SME) undergraduate degree recipients' subsequent enrollment in graduate study. This research utilizes 1994 data from the first follow-up of the 1993 Baccalaureate and Beyond Longitudinal Study by the National Center for Educational Statistics (NCES). Four groups of factors were examined---pre-college characteristics, personal characteristics, institutional characteristics, and the college experience. Analyses were conducted on the overall sample and by gender and race/ethnicity. Male and female subjects were equally likely to enroll in graduate school. White and non-White subjects were equally likely to enroll in graduate school. The best factor to predict enrollment in graduate study for all samples was cumulative grade point average. The models suggested, however, two different journeys taken by SME bachelor's degree recipients. Along one path taken by male and White students, factors associated with graduate school enrollment included having well-educated parents, at least a middle class family background, a good mathematics grade point average, being satisfied with the undergraduate curriculum, being less than twenty-three years old, and having participated in community service. Women and minority students, however, traveled a different path, where marriage negatively influenced enrollment in graduate study. In addition, having children and being over the age of twenty-three were negative factors for

  4. Examining factors that influence the effectiveness of cleaning antineoplastic drugs from drug preparation surfaces: a pilot study.

    Science.gov (United States)

    Hon, Chun-Yip; Chua, Prescillia Ps; Danyluk, Quinn; Astrakianakis, George

    2014-06-01

    Occupational exposure to antineoplastic drugs has been documented to result in various adverse health effects. Despite the implementation of control measures to minimize exposure, detectable levels of drug residual are still found on hospital work surfaces. Cleaning these surfaces is considered as one means to minimize the exposure potential. However, there are no consistent guiding principles related to cleaning of contaminated surfaces resulting in hospitals to adopt varying practices. As such, this pilot study sought to evaluate current cleaning protocols and identify those factors that were most effective in reducing contamination on drug preparation surfaces. Three cleaning variables were examined: (1) type of cleaning agent (CaviCide®, Phenokil II™, bleach and chlorhexidine), (2) application method of cleaning agent (directly onto surface or indirectly onto a wipe) and (3) use of isopropyl alcohol after cleaning agent application. Known concentrations of antineoplastic drugs (either methotrexate or cyclophosphamide) were placed on a stainless steel swatch and then, systematically, each of the three cleaning variables was tested. Surface wipes were collected and quantified using high-performance liquid chromatography-tandem mass spectrometry to determine the percent residual of drug remaining (with 100% being complete elimination of the drug). No one single cleaning agent proved to be effective in completely eliminating all drug contamination. The method of application had minimal effect on the amount of drug residual. In general, application of isopropyl alcohol after the use of cleaning agent further reduced the level of drug contamination although measureable levels of drug were still found in some cases.

  5. What do human factors and ergonomics professionals value in research publications? Re-examining the research-practice gap.

    Science.gov (United States)

    Chung, Amy Z Q; Williamson, Ann; Shorrock, Steven T

    2014-01-01

    The research-practice gap is of concern in human factors/ergonomics (HF/E) as there is a belief that HF/E research may not be making an impact on practice in the 'real world'. A potential issue is what researchers and practitioners perceive as important in HF/E journal articles as a primary means of conveying research findings to practitioners. This study examined the characteristics that make scientific journal articles appeal to HF/E researchers and practitioners using a web-based survey. HF/E researchers and practitioners were more similar than expected in judgements of important attributes and the selection of articles. Both practitioners and researchers considered practical significance to be more important than theoretical significance, in direct contrast to professionals from a related discipline--psychology. Well-written articles were appreciated across disciplines. The results signal a strong interest in practical applications in HF/E, but a relative lack of focus on development of theories that should be the basis for practical applications.

  6. Examining the Cervical Screening Behaviour of Women Aged 50 or above and Its Predicting Factors: A Population-Based Survey

    Directory of Open Access Journals (Sweden)

    Carmen W. H. Chan

    2016-12-01

    Full Text Available Under-screening may increase the risk of cervical cancer in middle-aged women. This study aimed to investigate cervical cancer screening behaviour and its predictors among women aged 50 years or above. A population-based sample of 959 women was recruited by telephone from domestic households in Hong Kong, using random methods, and a structured questionnaire developed to survey participants. Multivariable logistic regressions were performed to examine the factors independently associated with cervical screening behaviour. Nearly half the sample (48% had never had a cervical smear test. Multivariable analyses showed that age, educational level, marital status, family history of cancer, smoking status, use of complementary therapy, recommendation from health professionals, and believing that regular visits to a doctor or a Chinese herbalist were good for their health were predictors of cervical screening behaviour. Misconceptions concerned with menopause may reduce women’s perceived susceptibility to cervical cancer, especially if they are 50 or above, and exert a negative effect on their screening behaviour. Healthcare professionals should actively approach these high-risk groups–older unmarried women, smokers, those less educated and who are generally not much concerned with their health.

  7. Examining the relationship between sport and health among USA women:An analysis of the Behavioral Risk Factor Surveillance System

    Institute of Scientific and Technical Information of China (English)

    Jennifer R. Pharr; Nancy L. Lough

    2016-01-01

    Background: Research has been conducted linking sports participation and health in childhood and adolescence;however, little is known about the contribution of sport to women’s health. The purpose of this study was to examine the relationship between sport and women’s health in the USA by analyzing data from the Behavioral Risk Factor Surveillance System (BRFSS). Methods: This study was a secondary data analysis of the 2013 national BRFSS survey. Unlike the BRFSS core component from previous years, in 2013, participants were questioned extensively about their physical activity behaviors. Seventy-six different activities were identifie by the participants. Two researchers categorized the 76 activities as sport, conditioning exercise, recreation, or household tasks based on previously identifie categories. Logistic regression was utilized to calculate odds ratios and adjusted odds ratios for chronic diseases based on physical activity category. Results: Women who participated in sport had better health outcomes with significant y lower odds for all chronic diseases except asthma and better general health than women who participated in conditioning exercise, household tasks, or recreation, and many of the significan differences remained after controlling for demographic characteristics. Conclusion: Sport participation was associated with more positive health outcomes among women in the USA compared with the other categories. As a means to improve health of women, the USA could focus on efforts to increase sport participation among women.

  8. Examination of Oral Microbiota Diversity in Adults and Older Adults as an Approach to Prevent Spread of Risk Factors for Human Infections

    Directory of Open Access Journals (Sweden)

    Paweł J. Zawadzki

    2017-01-01

    Full Text Available The oral cavity environment may be colonized by polymicrobial communities with complex, poorly known interrelations. The aim of this study was to determine oral microbiota diversity in order to prevent the spread of infectious microorganisms that are risk factors for human health complications in patients requiring treatment due to various disabilities. The study examined Polish adults aged between 40 and 70 years; parasitological, microbiological, and mycological data collected before treatment were analyzed. The diversity of oral microbiota, including relatively high prevalences of some opportunistic, potentially pathogenic strains of bacteria, protozoans, and fungi detected in the patients analyzed, may result in increasing risk of disseminated infections from the oral cavity to neighboring structures and other organs. Increasing ageing of human populations is noted in recent decades in many countries, including Poland. The growing number of older adults with different oral health disabilities, who are more prone to development of oral and systemic pathology, is an increasing medical problem. Results of this retrospective study showed the urgent need to pay more attention to the pretreatment examination of components of the oral microbiome, especially to the strains, which are etiological agents of human opportunistic infections and are particularly dangerous for older adults.

  9. Ground-water heat pumps: an examination of hydrogeologic, environmental, legal, and economic factors affecting their use

    Energy Technology Data Exchange (ETDEWEB)

    Armitage, D M; Bacon, D J; Massey-Norton, J T; Miller, J D

    1980-11-12

    Groundwater is attractive as a potential low-temperature energy source in residential space-conditioning applications. When used in conjuncton with a heat pump, ground water can serve as both a heat source (for heating) and a heat sink (for cooling). Major hydrogeologic aspects that affect system use include groundwater temperature and availability at shallow depths as these factors influence operational efficiency. Ground-water quality is considered as it affects the performance and life-expectancy of the water-side heat exchanger. Environmental impacts related to groundwater heat pump system use are most influenced by water use and disposal methods. In general, recharge to the subsurface (usually via injection wells) is recommended. Legal restrictions on system use are often stricter at the municipal and county levels than at state and Federal levels. Although Federal regulations currently exist, the agencies are not equipped to regulate individual, domestic installations. Computer smulations indicate that under a variety of climatologic conditions, groundwater heat pumps use less energy than conventional heating and cooling equipment. Life-cycle cost comparisons with conventional equipment depend on alternative system choices and well cost options included in the groundwater heat pump system.

  10. The Levenson Self-Report Psychopathy Scale: An Examination of the Personality Traits and Disorders Associated with the LSRP Factors

    Science.gov (United States)

    Miller, Joshua D.; Gaughan, Eric T.; Pryor, Lauren R.

    2008-01-01

    There are several self-report measures of psychopathy, most of which use a two-factor structure. There is debate regarding the convergence of these factors, particularly with regard to Factor 1 (F1), which is related to the interpersonal and affective aspects of psychopathy; Factor 2 (F2) is related to the social deviance associated with…

  11. Motive,Predicament and Resolution in Including P .E . in College Entrance Examination%“高考体育”的动因、困境与出路

    Institute of Scientific and Technical Information of China (English)

    彭小伟

    2015-01-01

    The failure to include physical education in the college entrance examination during the new curriculum reform of the enrollment system has aroused widespread concern and brought controversy in the academic field .Based on the analy‐sis of the motive ,barrier and breakthrough of including physical education in the college entrance examination ,the authors held that the health of young people in China was a social issue .The inclusion should be realized through educational regu‐lations and governmental support .At present ,it was necessary to redesign the college entrance examination program of physical education ,to clarify the standard ,to make it feasible and consistent with the standard for physical education cur‐riculum and to meet the requirements for the international and national educational evaluation .%我国新一轮的考试招生制度改革并未将体育纳入高考的考试科目,在学校体育领域引起了广泛争议。对推动体育进入高考科目的动因、障碍及突破点进行分析后提出:青少年体质健康由单纯的教育问题上升为社会问题以及教育法规、行政手段的乏力是推动“高考体育”的现实基础;现有“高考体育”方案主要从体质健康评价视角进行设计,一方面是与青少年体质健康问题的简单直接对应关系所致,另一方面是受测试的操作性要求所限,但从体质健康评价视角设计的“高考体育”方案存在体质健康促进效应的短期化、干扰高中体育课程标准的达成、类同《国家学生体质健康标准》测试活动等不足。为顺应国际、国内教育评价的总体趋势与要求,与体育课程标准保持内在一致性,促进学校体育目标的总体达成,当前需要从学科能力评价的视角对“高考体育”方案进行重新设计,其中应解决体育学科能力概念的澄清、界定、操作化设计、学段标准制定等关键环节问题。

  12. Consequences of introducing requirements for tanks prepared for solar heating in the building regulations including examinations of bacteria risks; Konsekvenser ved solvarmeforberedte beholdere i bygningsreglementet herunder undersoegelse af risici for bakteriegener

    Energy Technology Data Exchange (ETDEWEB)

    Ellehauge, K.; Kaersgaard, K. [Teknologisk Inst., SolEnergiCentret, Taastrup (Denmark); Bagh, L. [Teknologisk Inst., Miljoedivisionen (Denmark)

    2000-07-01

    A larger dissemination of solar heating units must be expected, if requirements for tanks prepared for solar heating are introduced in the building regulations. However, this may have effects, which have to be discussed beforehand, just as it has to be decided how the regulations can be put into practice. 1) The aim is to examine and discuss the consequences of introducing requirements for tanks prepared for solar heating in the building regulations including connections with other legislation, potential, consequences for the building services sector and proposals for rules in the building regulations (exceptions etc.) 2) Furthermore, the aim is to explain the risk of bacteria in tanks prepared for solar heating according to existing or new additional studies. It must be explained whether tanks prepared for solar heating will result in an increased number of bacteria in the water compared to traditional hot water tanks and - if possible - whether the change is caused by the increased volume of the tank (the water stays in the tank for a longer period) or changed temperature conditions which favours growth of bacteria at a certain incubation temperature. (EHS)

  13. Including the spatial variability of metal speciation in the effect factor in life cycle impact assessment: Limits of the equilibrium partitioning method.

    Science.gov (United States)

    Tromson, Clara; Bulle, Cécile; Deschênes, Louise

    2017-03-01

    In life cycle assessment (LCA), the potential terrestrial ecotoxicity effect of metals, calculated as the effect factor (EF), is usually extrapolated from aquatic ecotoxicological data using the equilibrium partitioning method (EqP) as it is more readily available than terrestrial data. However, when following the AMI recommendations (i.e. with at least enough species that represents three different phyla), there are not enough terrestrial data for which soil properties or metal speciation during ecotoxicological testing are specified to account for the influence of soil property variations on metal speciation when using this approach. Alternatively, the TBLM (Terrestrial Biotic Ligand Model) has been used to determine an EF that accounts for speciation, but is not available for metals; hence it cannot be consistently applied to metals in an LCA context. This paper proposes an approach to include metal speciation by regionalizing the EqP method for Cu, Ni and Zn with a geochemical speciation model (the Windermere Humic Aqueous Model 7.0), for 5213 soils selected from the Harmonized World Soil Database. Results obtained by this approach (EF(EqP)regionalized) are compared to the EFs calculated with the conventional EqP method, to the EFs based on available terrestrial data and to the EFs calculated with the TBLM (EF(TBLM)regionalized) when available. The spatial variability contribution of the EF to the overall spatial variability of the characterization factor (CF) has been analyzed. It was found that the EFs(EqP)regionalized show a significant spatial variability. The EFs calculated with the two non-regionalized methods (EqP and terrestrial data) fall within the range of the EFs(EqP)regionalized. The EFs(TBLM)regionalized cover a larger range of values than the EFs(EqP)regionalized but the two methods are not correlated. This paper highlights the importance of including speciation into the terrestrial EF and shows that using the regionalized EqP approach is not an

  14. PHARMACOECONOMIC ASPECTS OF TREATMENT WITH THE INHIBITORS OF TUMOR NECROSIS FACTOR OF THE CHRONIC UVEITIS REFRACTORY TO THE BASIC THERAPY (INCLUDING AN ASSOCIATED WITH JUVENILE IDIOPATHIC ARTHRITIS

    Directory of Open Access Journals (Sweden)

    A.V. Rudakova

    2011-01-01

    Full Text Available Therapy of chronic uveitis refractory to the basic treatment, in juvenile idiopathic arthritis (JIA is a very complex problem in pediatrics. Substantial progress in this area resulted after the implementation in practice of inhibitors of tumor necrosis factor (TNF, as the most effective in such clinical situation drugs adalimumab and infliximab are considered (although infliximab was not officially approved in JIA. Objective. To estimate the cost effectiveness of TNF inhibitors — adalimumab, and infliximab in chronic uveitis, refractory to the basic therapy (including associated with juvenile rheumatoid arthritis. Methods. A modeling on the basis of a comparative prospective cohort clinical study was carried out. The analysis was performed by the method «cost–effectiveness» from a position of health and social accounting perspective. Results. It was shown that the frequency and time of remission did not differ when treatment with infliximab (5 mg/kg at 0–2–6 weeks and further once in 6–8 weeks and adalimumab (24 mg/m2 once in 2 weeks. Adalimumab provides a long-term maintenance of remission (no recurrence in 60% of patients within 40 months of observation, whereas 1 year after the treatment with infliximab the frequency of exacerbations was returned to that observed before therapy. The proportion of patients without relapse in the treatment with infliximab for 40 months was 18.8%. Similar results were obtained in a subset of patients with chronic uveitis associated with JIA (with follow-up of 20 months of in a group of infliximab number patients without relapse was 11.1%, with adalimumab therapy — 63.6%. In the general population of patients with refractory chronic uveitis the factor «cost–effectiveness» calculated for a patient with the maintenance of remission for 3 years with adalimumab therapy was in 2,1–2,8 times less than in the treatment with infliximab. In chronic uveitis associated with JIA, the coefficient of

  15. Psychosocial and behavioral factors associated with risk of sexually transmitted diseases, including human immunodeficiency virus infection, among urban high school students.

    Science.gov (United States)

    Shafer, M A; Boyer, C B

    1991-11-01

    The main purpose of this study was to evaluate the role of multiple psychosocial and knowledge-related antecedent factors that may predict sexual and alcohol and drug use behaviors that are associated with the transmission of sexually transmitted diseases (STDs), including human immunodeficiency virus infection. Five hundred forty-four ninth-grade urban high school students were surveyed regarding knowledge, attitudes, and behaviors related to STDs and acquired immunodeficiency syndrome (AIDS). Results of multiple regression analyses indicate that higher levels of STD and AIDS knowledge were associated with lower levels of STD and AIDS anxiety (R2 delta = 0.09; p less than 0.001), fewer negative attitudes toward people with AIDS (R2 delta = 0.09; p less than 0.001), stronger perceptions of self-efficacy (R2 delta = 0.03; p less than 0.01), and stronger peer affiliation (R2 delta = 0.02; p less than 0.05). Negative attitudes toward people with AIDS were inversely related to knowledge (R2 delta = 0.08; p less than 0.001), social support (R2 delta = 0.02; p less than 0.01), and perceived self-efficacy (R2 delta = 0.01; p less than 0.05). Predictors of alcohol and drug use included perceived peer norms (R2 delta = 0.08; p less than 0.001) and strong peer affiliation (R2 delta = 0.05; p less than 0.001). The best predictor of sexual risk behavior was alcohol and drug use (R2 delta = 0.07; p less than 0.001). Lower levels of knowledge (R2 delta = 0.14; p less than 0.01) and perceived peer norms (R2 delta = 0.05; p less than 0.05) predicted nonuse of condoms. Our results indicate that several factors relate to adolescent risk for STDs: the connection between peer influence and adolescent risk behaviors, the link between alcohol and drug use and sexual risk behavior, and the role of knowledge in determining nonuse of condoms.

  16. A longitudinal examination of risk and protective factors for cigarette smoking among lesbian, gay, bisexual, and transgender youth.

    Science.gov (United States)

    Newcomb, Michael E; Heinz, Adrienne J; Birkett, Michelle; Mustanski, Brian

    2014-05-01

    To investigate change across development in two smoking outcomes (smoking status and rate), describe demographic differences in smoking, and longitudinally examine the effects of psychosocial variables on smoking (psychological distress, victimization, and social support) in lesbian, gay, bisexual, and transgender (LGBT) youth. Participants were 248 ethnically diverse LGBT youth (ages 16-20 years at baseline) from a longitudinal cohort study with six waves over 3.5 years. Baseline questionnaires included demographic variables and a measure of impulsivity, and longitudinal questionnaires included measures of cigarette smoking (status and average number of cigarettes smoked daily), LGBT-based victimization, psychological distress, and perceived social support. Analyses were conducted with hierarchical linear modeling. Males had higher odds of smoking and smoking rate than females, but females' smoking rate increased more rapidly over time. Psychological distress was associated with higher odds of smoking and smoking rate at the same wave, and it predicted smoking rate at the subsequent wave. LGBT victimization was associated with higher odds of smoking at the same wave and predicted smoking rate at the subsequent wave. Finally, significant other support predicted higher odds of smoking and smoking rate at the subsequent wave, but family support was negatively correlated with smoking rate at the same wave. There are several viable avenues for the development of smoking prevention interventions for LGBT youth. To optimize the efficacy of prevention strategies, we must consider experiences with victimization, the impact of psychological distress, and optimizing support from families and romantic partners. Copyright © 2014 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  17. Diet and food insufficiency among Hispanic youths: acculturation and socioeconomic factors in the third National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Mazur, Robert E; Marquis, Grace S; Jensen, Helen H

    2003-12-01

    Low socioeconomic status is associated with poor diet, food insufficiency, and poor child health. Hispanic households have disproportionately low incomes. Acculturation-related changes may augment the effects of poverty on children's diet and health. The goal was to determine the associations that acculturation, measured by parents' language use, and income have with dietary intakes and food insufficiency among Hispanic youths. Data on 2985 Hispanic youths aged 4-16 y were from the third National Health and Nutrition Examination Survey (1988-1994). Nutrient intake data were from one 24-h dietary recall. The analysis was controlled for demographic, socioeconomic, and program variables. Parents' exclusive use of Spanish was associated in bivariate analyses with differences in intakes of energy, protein, sodium, and folate and in percentages of energy from fat and saturated fat. When other factors were controlled for, less acculturation was associated with differences in intakes of energy and sodium and in percentages of energy from fat and saturated fat. Individuals in poorer households had higher intakes of energy, protein, sodium, and some micronutrients. Although not significant for all indicators of food insufficiency, consistent patterns showed that household food insufficiency decreased with less acculturation (odds ratio: 0.4; 95% CI: 0.2, 0.7 for adult meal size reduced) and increased with low income [odds ratio: 5.9 (3.0, 11.7) for not enough food and 5.4 (2.2, 13.4) for child meal size reduced]. Both acculturation and poverty have roles in children's diets and in household food insufficiency. Culturally specific public health and nutrition education should complement efforts to improve the financial security of low-income households.

  18. Factors Affecting of Attitude in Breast Self-Examination among Fertile Age Women in Wosi Sub District of West Manokwari

    Directory of Open Access Journals (Sweden)

    Jeane Caroline Etwiory

    2016-12-01

    Full Text Available Abstract In 2010 the WHO (World Health Organization estimates that the incidence of breast cancer are 11 million and in 2030 will grow to 27 million cancer deaths. Ministry of Health, there are about 80 cases of breast cancer in the province of West Papua. This is not as much as the one in Papua province whose cases reached 466 cases of breast cancer. The factors that influence the actions breast self examination (BSE in women of childbearing age in the Wosi sub district, western Manokwari. Methods: This cross-sectional observational study design. Cross-sectional study. Women of fertile age population is 259 and 157 samples. Results indicated that there was an effect of age with action (p-value 0.000 RP = Lower 0.102-Upper 0.519, no effect of recent education (p-value 0.516 RP = Lower 1.479 - Upper 1.919, there was no effect of the work (p-value 0.406 RP = Lower 0.714 - Upper 2.671, there was no effect of Social Economy (p-value 1.000 RP = Lower .545 - Upper 1.958, there was the influence of Information (p-value 0.000 RP = Lower 3,022 - Upper 15.383, there is no influence of Knowledge ( p-value 0.840 0.410 RP = Lower - Upper 2.023, there is no influence of attitude (p-value 0.316 RP = Lower 0,493- Upper 12.218, there is the influence of Family Support (p-value 0.000 RP = Lower 3,186- Upper 13.175.

  19. Examining risk and protective factors for alcohol use in lesbian, gay, bisexual, and transgender youth: a longitudinal multilevel analysis.

    Science.gov (United States)

    Newcomb, Michael E; Heinz, Adrienne J; Mustanski, Brian

    2012-09-01

    Lesbian, gay, bisexual, and transgender (LGBT) youth are at increased risk for alcohol misuse, but little is known about the psychosocial and demographic factors that are associated with these differences over time. The purpose of this study was to investigate change in alcohol use across development. We aimed to describe group/demographic differences in alcohol use, the effects of psychosocial variables on drinking within persons (i.e., psychological distress, sexual orientation-based victimization, and perceived family support), and the interactions between demographic differences and longitudinal psychosocial variables in predicting rates of alcohol use. The current study used data from the longest running longitudinal study of LGBT youth. Hierarchical linear modeling was used to examine both demographic differences and psychosocial predictors of alcohol use in an ethnically diverse sample of 246 LGBT youth (ages 16-20 years at baseline) across five time points over 2.5 years. Drinking increased significantly over time in a linear fashion, although it tended to increase more rapidly among male LGBT youth compared with females. Analyses of group differences revealed lower average rates of drinking for African American and female LGBT youth, and there were no differences between bisexual youth and gay/lesbian youth. Psychological distress and sexual orientation-based victimization were associated with increased alcohol use at each wave of data collection for female LGBT youth only. Perceived family support at each wave was negatively associated with alcohol use for all LGBT youth. Findings indicate that there is significant heterogeneity in the etiological pathways that lead to alcohol use in LGBT youth and that correlates of drinking are similar to those found in general populations. These crucial findings indicate that existing alcohol interventions also may be effective for LGBT youth and open up a wider array of prevention and treatment options for this at

  20. Examining the factor structure of the Clinical Opiate Withdrawal Scale: A secondary data analysis from the National Drug Abuse Treatment Clinical Trials Network (CTN) 0003.

    Science.gov (United States)

    Barbosa-Leiker, Celestina; McPherson, Sterling; Mamey, Mary Rose; Burns, G Leonard; Layton, Matthew E; Roll, John; Ling, Walter

    2015-07-01

    The Clinical Opiate Withdrawal Scale (COWS) is used to assess withdrawal in clinical trials and practice. The aims of this study were to examine the inter-item correlations and factor structure of the COWS in opioid-dependent men and women. This is a secondary data analysis of the National Drug Abuse Treatment Clinical Trials Network 0003, a randomized clinical trial that compared buprenorphine/naloxone tapering strategies. The trial included 11 sites in 10 US cities. Participants were opioid-dependent individuals (n=516) that had data on the COWS. The COWS at study baseline was analyzed in this study. Inter-item correlations showed weak to moderate relationships among the items. A 1-factor model did not fit the data for men (comparative fit index (CFI)=.801, root mean square error of approximation (RMSEA)=.073, weighted root mean square residual (WRMR)=1.132) or women (CFI=.694, RMSEA=.071, WRMR=.933), where resting pulse rate was not related to withdrawal for men, and yawning and gooseflesh skin was not related to withdrawal for women. A reduced model comprised of only the 8 items that were significantly related to the construct of withdrawal in both men and women, and an exploratory 2-factor model, were also assessed but not retained due to inconsistencies across gender. When traditional psychometric models are applied to the COWS, it appears that the scale may not relate to a single underlying construct of withdrawal. Further research testing the hypothesized factor structure in other opioid-dependent samples is needed. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  1. Examining the factor structure of the Clinical Opiate Withdrawal Scale: A secondary data analysis from the National Drug Abuse Treatment Clinical Trials Network (CTN) 0003

    Science.gov (United States)

    Barbosa-Leiker, Celestina; McPherson, Sterling; Mamey, Mary Rose; Burns, G. Leonard; Layton, Matthew E.; Roll, John; Ling, Walter

    2015-01-01

    Background The Clinical Opiate Withdrawal Scale (COWS) is used to assess withdrawal in clinical trials and practice. The aims of this study were to examine the inter-item correlations and factor structure of the COWS in opioid-dependent men and women. Methods This is a secondary data analysis of the National Drug Abuse Treatment Clinical Trials Network 0003, a randomized clinical trial that compared buprenorphine/naloxone tapering strategies. The trial included 11 sites in 10 US cities. Participants were opioid-dependent individuals (n=516) that had data on the COWS. The COWS at study baseline was analyzed in this study. Results Inter-item correlations showed weak to moderate relationships among the items. A 1-factor model did not fit the data for men (comparative fit index (CFI)=.801, root mean square error of approximation (RMSEA)=.073, weighted root mean square residual (WRMR)=1.132) or women (CFI=.694, RMSEA=.071, WRMR=.933), where resting pulse rate was not related to withdrawal for men, and yawning and gooseflesh skin was not related to withdrawal for women. A reduced model comprised of only the 8 items that were significantly related to the construct of withdrawal in both men and women, and an exploratory 2-factor model, were also assessed but not retained due to inconsistencies across gender. Conclusions When traditional psychometric models are applied to the COWS, it appears that the scale may not relate to a single underlying construct of withdrawal. Further research testing the hypothesized factor structure in other opioid-dependent samples is needed. PMID:25908321

  2. Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and Risk Factors

    Directory of Open Access Journals (Sweden)

    Yohei Kawatani

    2016-01-01

    Full Text Available Endovascular stent graft placement has become a major treatment for thoracic and abdominal aneurysms. While endovascular therapy is less invasive than open surgery, it involves the use of a contrast medium. Contrast media can cause renal impairment, a condition termed as contrast-induced nephropathy (CIN. This study sought to evaluate the incidence and risk factors of CIN following endovascular stent graft placement for aortic aneurysm repair. The study included 167 consecutive patients who underwent endovascular stent graft placement in our hospital from October 2013 to June 2014. CIN was diagnosed using the European Society of Urogenital Radiology criteria. Patients with and without CIN were compared. Chi-squared tests, t-tests, and multivariate logistic regression analyses were performed. Thirteen patients (7.8% developed CIN. Left ventricular dysfunction and intraoperative blood transfusion were significantly more frequent in the CIN group (P=0.017 and P=0.032, resp.. Multivariate analysis showed that left ventricular dysfunction had the strongest influence on CIN development (odds ratio 9.34, P=0.018, and 95% CI = 1.46–59.7. Patients with CIN also experienced longer ICU and hospital stays. Measures to improve renal perfusion flow should be considered for patients with left ventricular dysfunction who are undergoing endovascular stent graft placement.

  3. Long-term maintenance of reducing conditions in a spent nuclear fuel repository. A re-examination of critical factors

    Energy Technology Data Exchange (ETDEWEB)

    Gascoyne, M. [Gascoyne GeoProjects Inc, Pinawa, MB (Canada)

    1999-04-01

    Penetration of oxidising groundwaters to depths of 500 m in a permeable bedrock, over a glacial/interglacial cycle, may compromise the stability of a spent nuclear fuel repository and cause the release and migration towards the surface of actinides and associated fission products. This report examines the potential for the penetration of oxygen (O{sub 2}) to depths of 500 m in a fractured crystalline rock environment, typical of the Fennoscandian Shield. Previous studies performed for the Swedish program of nuclear waste disposal (principally the SITE-94 safety assessment) have indicated that O{sub 2} might reach repository depths during a deglaciation when melt-water from the base of an ice sheet could enter the bedrock, driven by strong hydraulic gradients. This report re-examines aspects of this scenario and finds that: 1. The capacity of flow-path minerals to scavenge O{sub 2} from recharging groundwater may be lower than expected due to a previously unrecognised depletion of Fe(II)-bearing minerals in the active flow-paths in a fractured crystalline rock. 2. Assumptions in the SITE-94 assessment, such as the use of a continental-scale flow model, the lack of structural controls on groundwater flow, a preferred horizontal permeability, and the use of permeabilities to depths of 10 km that are up to two orders of magnitude greater than comparable environments, are disproportionately simplistic and represent an extremely conservative case. 3. Assumptions of a thin, discontinuous permafrost, a warm-based ice sheet, and high-O{sub 2} content melt-water at the repository site are unrealistic and overly conservative. A more realistic scenario, which includes a greater influence of permafrost, a cold based ice sheet, lower bedrock permeabilities and a more-limited, regional-scale flow path, is recommended as being more appropriate for use in the safety assessment. Under this revised scenario, it is believed that O{sub 2} will not penetrate to repository depths over

  4. Dietary Very Long Chain Saturated Fatty Acids and Metabolic Factors: Findings from the Korea National Health and Nutrition Examination Survey 2013.

    Science.gov (United States)

    Lee, Youn Sue; Cho, Yoonsu; Shin, Min-Jeong

    2015-07-01

    The present study was aim to evaluate the association between very long chain saturated fatty acids (VLSFAs) and metabolic syndrome (MetS) in Korean population. The study population were recruited from the Korea National Health and Nutrition Examination Survey VI (2013). Using the cross-sectional study design, socio-demographic factors, medical history, and clinical measurements were investigated according to quartiles of VLSFAs intake. The associations between each and sum of VLSFAs intake and MetS were assessed by logistic regression. The result indicated that higher intake of VLSFAs was significantly associated with favorable metabolic status, including lower levels of circulating triglyceride (TG) (p < 0.05). Additionally, subjects with higher intake of arachidic acid and total VLSFAs were negatively associated with MetS risk compared to subjects with lower intake of those fatty acids (p < 0.05). In conclusion, dietary VLSFAs intake was associated with metabolic risk factors and lower risk of MetS in Korean population.

  5. Examining critical factors affecting graduate retention from an emergency medicine training program in Addis Ababa, Ethiopia: a qualitative study of stakeholder perspectives

    Directory of Open Access Journals (Sweden)

    Meredith Jane Kuipers

    2017-04-01

    Full Text Available Background: In Ethiopia, improvement and innovation of the emergency care system is hindered by lack of specialist doctors trained in emergency medicine, underdeveloped emergency care infrastructure, and consumable resource limitations. Our aim was to examine the critical factors affecting retention of graduates from the Addis Ababa University (AAU post-graduate emergency medicine (EM training program within the Ethiopian health care system. Methods: Qualitative interviews were conducted with current AAU EM residents and stakeholders in Ethiopian EM. Mixed-methods inductive thematic analysis was performed. Results: Resident and stakeholder participants identified critical factors in three domains: the individual condition, the occupational environment, and the national context. Within each domain, priority themes emerged from the responses, including the importance of career satisfaction over the career continuum (individual condition, the opportunity to be involved in the developing EM program and challenges associated with resource, economic, and employment constraints (occupational environment, and perceptions regarding the state of awareness of EM and the capacity for change at the societal level (national context. Conclusions: This work underscores the need to resolve multiple systemic and cultural issues within the Ethiopian health care landscape in order to address EM graduate retention. It also highlights the potential success of a retention strategy focused on the career ambitions of keen EM doctors.

  6. Retrospective multicenter matched case-control study on the risk factors for narcolepsy with special focus on vaccinations (including pandemic influenza vaccination) and infections in Germany.

    Science.gov (United States)

    Oberle, Doris; Pavel, Jutta; Mayer, Geert; Geisler, Peter; Keller-Stanislawski, Brigitte

    2017-06-01

    Studies associate pandemic influenza vaccination with narcolepsy. In Germany, a retrospective, multicenter, matched case-control study was performed to identify risk factors for narcolepsy, particularly regarding vaccinations (seasonal and pandemic influenza vaccination) and infections (seasonal and pandemic influenza) and to quantify the detected risks. Patients with excessive daytime sleepiness who had been referred to a sleep center between April 2009 and December 2012 for multiple sleep latency test (MSLT) were eligible. Case report forms were validated according to the criteria for narcolepsy defined by the Brighton Collaboration (BC). Confirmed cases of narcolepsy (BC level of diagnostic certainty 1-4a) were matched with population-based controls by year of birth, gender, and place of residence. A second control group was established including patients in whom narcolepsy was definitely excluded (test-negative controls). A total of 103 validated cases of narcolepsy were matched with 264 population-based controls. The second control group included 29 test-negative controls. A significantly increased odd ratio (OR) to develop narcolepsy (crude OR [cOR] = 3.9, 95% confidence interval [CI] = 1.8-8.5; adjusted OR [aOR] = 4.5, 95% CI = 2.0-9.9) was detected in individuals immunized with pandemic influenza A/H1N1/v vaccine prior to symptoms onset as compared to nonvaccinated individuals. Using test-negative controls, in individuals immunized with pandemic influenza A/H1N1/v vaccine prior to symptoms onset, a nonsignificantly increased OR of narcolepsy was detected when compared to nonvaccinated individuals (whole study population, BC levels 1-4a: cOR = 1.9, 95% CI = 0.5-6.9; aOR = 1.8, 95% CI = 0.3-10.1). The findings of this study support an increased risk for narcolepsy after immunization with pandemic influenza A/H1N1/v vaccine. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Multiple factors, including non-motor impairments, influence decision making with regard to exercise participation in Parkinson's disease: a qualitative enquiry.

    Science.gov (United States)

    O'Brien, Christine; Clemson, Lindy; Canning, Colleen G

    2016-01-01

    To explore how the meaning of exercise and other factors interact and influence the exercise behaviour of individuals with Parkinson's disease (PD) enrolled in a 6-month minimally supervised exercise program to prevent falls, regardless of whether they completed the prescribed exercise or not. This qualitative study utilised in-depth semi-structured interviews analysed using grounded theory methodology. Four main themes were constructed from the data: adapting to change and loss, the influence of others, making sense of the exercise experience and hope for a more active future. Participation in the PD-specific physiotherapy program involving group exercise provided an opportunity for participants to reframe their identity of their "active" self. Three new influences on exercise participation were identified and explored: non-motor impairments of apathy and fatigue, the belief in a finite energy quota, and the importance of feedback. A model was developed incorporating the themes and influences to explain decision-making for exercise participation in this group. Complex and interacting issues, including non-motor impairments, need to be considered in order to enhance the development and ongoing implementation of effective exercise programmes for people with PD. Exercise participation can assist individuals to reframe their identity as they are faced with losses associated with Parkinson's disease and ageing. Non-motor impairments of apathy and fatigue may influence exercise participation in people with Parkinson's disease. Particular attention needs to be paid to the provision of feedback in exercise programs for people with Parkinson's disease as it important for their decision-making about continuing exercise.

  8. Retrospective analysis of factors associated with outcome of proximal interphalangeal joint arthrodesis in 82 horses including Warmblood and Thoroughbred sport horses and Quarter Horses (1992-2014).

    Science.gov (United States)

    Herthel, T D; Rick, M C; Judy, C E; Cohen, N D; Herthel, D J

    2016-09-01

    Outcomes associated with arthrodesis of the proximal interphalangeal (PIP) joint in Quarter Horses used for Western performance activities are well documented but little is known regarding outcomes for other types of horses. To identify factors associated with outcomes, including breed and activity, after arthrodesis of the PIP joint in Warmbloods, Thoroughbreds and Quarter Horses. Retrospective case series. Surgical case records of 82 Quarter Horses principally engaged in Western performance and Thoroughbred or Warmblood breeds principally engaged in showing, showjumping and dressage, with arthrodesis of the PIP joint were reviewed. Arthrodesis was performed with either 3 transarticular cortex bone screws placed in lag fashion, a dynamic compression plate (DCP) with 2 transarticular cortex bone screws placed in lag fashion, or a locking compression plate (LCP) with 2 transarticular cortex bone screws placed in lag fashion. Demographic data, clinical presentation, radiographic findings, surgical technique, post operative treatment and complications were recorded. Long-term follow-up was obtained for all 82 horses. Osteoarthritis of the PIP joint was the most common presenting condition requiring arthrodesis, which was performed with either the 3 screw technique (n = 41), DCP fixation (n = 22), or LCP fixation (n = 19). Post operatively, 23/31 (74%) Warmbloods/Thoroughbreds and 44/51 (87%) Quarter Horses achieved successful outcomes. Thirteen of 23 (57%) Warmbloods/Thoroughbreds and 24 of 38 (63%) Quarter Horses, used for athletic performance, returned to successful competition. Within this subgroup of horses engaged in high-level activity, regardless of breed type, horses undergoing hindlimb arthrodesis were significantly more likely to return to successful competition (73%; 33/45) than those with forelimb arthrodesis (25%; 4/16, P = 0.002). Arthrodesis of the PIP joint in Warmbloods/Thoroughbreds and Quarter Horses results in a favourable outcome for return to

  9. Laser Microdissection Unravels Cell-Type-Specific Transcription in Arbuscular Mycorrhizal Roots, Including CAAT-Box Transcription Factor Gene Expression Correlating with Fungal Contact and Spread1[W

    Science.gov (United States)

    Hogekamp, Claudia; Arndt, Damaris; Pereira, Patrícia A.; Becker, Jörg D.; Hohnjec, Natalija; Küster, Helge

    2011-01-01

    Arbuscular mycorrhizae (AM) are the most widespread symbioses on Earth, promoting nutrient supply of most terrestrial plant species. To unravel gene expression in defined stages of Medicago truncatula root colonization by AM fungi, we here combined genome-wide transcriptome profiling based on whole mycorrhizal roots with real-time reverse transcription-PCR experiments that relied on characteristic cell types obtained via laser microdissection. Our genome-wide approach delivered a core set of 512 genes significantly activated by the two mycorrhizal fungi Glomus intraradices and Glomus mossae. Focusing on 62 of these genes being related to membrane transport, signaling, and transcriptional regulation, we distinguished whether they are activated in arbuscule-containing or the neighboring cortical cells harboring fungal hyphae. In addition, cortical cells from nonmycorrhizal roots served as a reference for gene expression under noncolonized conditions. Our analysis identified 25 novel arbuscule-specific genes and 37 genes expressed both in the arbuscule-containing and the adjacent cortical cells colonized by fungal hyphae. Among the AM-induced genes specifying transcriptional regulators were two members encoding CAAT-box binding transcription factors (CBFs), designated MtCbf1 and MtCbf2. Promoter analyses demonstrated that both genes were already activated by the first physical contact between the symbionts. Subsequently, and corresponding to our cell-type expression patterns, they were progressively up-regulated in those cortical areas colonized by fungal hyphae, including the arbuscule-containing cells. The encoded CBFs thus represent excellent candidates for regulators that mediate a sequential reprogramming of root tissues during the establishment of an AM symbiosis. PMID:22034628

  10. An Examination of Tri-Level Collaboration around Student Achievement Using the Gap Analysis Approach: Teacher Factors

    Science.gov (United States)

    Carruthers, Anthony Steven

    2013-01-01

    Using the Gap Analysis problem-solving framework (Clark & Estes, 2008), this project examined collaboration around student achievement in the Pasadena Unified School District (PUSD) from the teacher perspective. As part of a tri-level study, two other projects examined collaboration around student achievement in PUSD from the perspectives of…

  11. Education and adult cause-specific mortality--examining the impact of family factors shared by 871 367 Norwegian siblings

    DEFF Research Database (Denmark)

    Næss, Oyvind; Hoff, Dominic A; Lawlor, Debbie;

    2012-01-01

    To estimate the impact family factors shared by siblings has on the association between length of education and cause-specific mortality in adulthood.......To estimate the impact family factors shared by siblings has on the association between length of education and cause-specific mortality in adulthood....

  12. The Examination of Factors Influencing Social Media Usage by African American Small Business Owners Using the UTAUT Model

    Science.gov (United States)

    Serben, Dion F.

    2014-01-01

    The unified theory of acceptance and use of technology (UTAUT) model has demonstrated the influencing factors for various business technology uses within the organizational system. However, in the context of African American small businesses (AASB), there was very little evidence of research to determine factors affecting the intention to use…

  13. Social Factors that Impact Women's Practice of Breast Self-Examination: A Challenge to the Transfer of Training Literature

    Science.gov (United States)

    London, Patricia A.; Flannery, Daniele D.

    2004-01-01

    The purpose of the qualitative study was to understand how social factors might help or hinder the training transfer process. Specifically, this qualitative research looked at the meanings a group of women attached to social factors that might influence their practice of breast self-exam. Implications for transfer of training are suggested.…

  14. Examining factors affecting beginning teachers’ transfer of learning of ICT-enhanced learning activities in their teaching practice

    NARCIS (Netherlands)

    Voogt, Joke; Agyei, Douglas; McBride, Ron; Searson, Michael

    2013-01-01

    This study examined 100 beginning teachers’ transfer of learning in utilizing Information Communication Technology-enhanced activity-based learning activities. The beginning teachers had participated in a professional development program characterized by ‘learning technology by collaborative design’

  15. The Association between leisure time physical activity and smoking in adolescence: an examination of potential mediating and moderating factors

    DEFF Research Database (Denmark)

    Verkooijen, Kirsten; Nielsen, Gert A; Kremers, Stef P J

    2008-01-01

    BACKGROUND: Although physical activity has been associated negatively with smoking in adolescence, the association is not well understood. PURPOSE: This study examines the relationship between adolescents' leisure time physical activity and smoking behavior, while considering BMI, weight concern,...

  16. The association between leisure time physical activity and smoking in adolescence: an examination of potential mediating and moderating factors

    NARCIS (Netherlands)

    Verkooijen, K.T.; Nielsen, G.A.; Kremers, S.P.J.

    2008-01-01

    Although physical activity has been associated negatively with smoking in adolescence, the association is not well understood. Purpose: This study examines the relationship between adolescents' leisure time physical activity and smoking behavior, while considering BMI, weight concern, sense of coher

  17. Examining factors affecting beginning teachers' transfer of learning of ICT-enhanced learning activities in their teaching practice

    NARCIS (Netherlands)

    Agyei, D.D.; Voogt, J.

    2014-01-01

    This study examined 100 beginning teachers’ transfer of learning when utilising Information Communication Technology-enhanced activity-based learning activities. The beginning teachers had participated in a professional development program that was characterised by ‘learning technology by

  18. Examining factors affecting beginning teachers’ transfer of learning of ICT-enhanced learning activities in their teaching practice

    NARCIS (Netherlands)

    Voogt, Joke; Agyei, Douglas; McBride, Ron; Searson, Michael

    2013-01-01

    This study examined 100 beginning teachers’ transfer of learning in utilizing Information Communication Technology-enhanced activity-based learning activities. The beginning teachers had participated in a professional development program characterized by ‘learning technology by collaborative design’

  19. Analysis of the Influence Factors and Countermeasures of Physical Examination Nursing Quality%体检护理质量的影响因素与对策分析

    Institute of Scientific and Technical Information of China (English)

    陈淑艳

    2015-01-01

    Objective To study the influence factors and countermeasures of physical examination nursing quality. Methods The nursing data of physical examination center of our hospital during May 2013 to May 2014 were analyzed retrospectively, the influence factors of physical examination nursing quality were investigated, the improvement strategy were put forward. Results The influence factors of physical examination nursing quality included the quality of nursing staff, facilities, environment of physical examination center. The satisfaction of physical examination nursing after improvement were significantly higher than that before improvement, the difference was statistical y significant (P<0.05). Conclusion The influence factors of physical examination nursing quality are determined, and the nursing methods are improved on this basis, it is very useful for the improvement of physical examination nursing quality and the satisfaction of physical examination nursing.%目的:探讨影响体检护理质量的相关因素及解决对策。方法回顾分析2013年5月~2014年5月我院体检中心的相关护理资料,调查影响体检护理质量的相关因素,并提出改进策略。结果影响体检护理质量的因素:护理人员素质、仪器设施、体检中心环境。改进后体检者的护理总满意度显著高于改进前,差异有统计学意义(P<0.05)。结论明确影响体检护理质量的相关因素,并以此作出改进,对提升体检护理质量及体检者满意度极其有益。

  20. Using bifactor exploratory structural equation modeling to examine global and specific factors in measures of sports coaches’ interpersonal styles

    Directory of Open Access Journals (Sweden)

    Andreas eStenling

    2015-09-01

    Full Text Available In the present work we investigated distinct sources of construct-relevant psychometric multidimensionality in two sport-specific measures of coaches’ need-supportive (ISS-C and controlling interpersonal (CCBS styles. A recently proposed bifactor exploratory structural equation modeling (ESEM framework was employed to achieve this aim. In Study 1, using a sample of floorball players, the results indicated that the ISS-C can be considered as a unidimensional measure, with one global factor explaining most of the variance in the items. In Study 2, using a sample of male ice hockey players, the results indicated that the items in the CCBS are represented by both a general factor and specific factors, but the subscales differ with regard to the amount of variance in the items accounted for by the general and specific factors. These results add further insight into the psychometric properties of these two measures and the dimensionality of these two constructs.

  1. [The development of the Japanese version of the Maslach Burnout Inventory and the examination of the factor structure].

    Science.gov (United States)

    Higashiguchi, K; Morikawa, Y; Miura, K; Nishijo, M; Tabata, M; Yoshita, K; Sagara, T; Nakagawa, H

    1998-07-01

    This article presents an evaluation of the factor structures of the Japanese version of the Maslach Burnout Inventory (MBI). The MBI is a widely used psychometric instrument for measuring 'burnout' developed by Maslach and her co-workers. The MBI consists of four subscales: Emotional Exhaustion, Personal Accomplishment, Depersonalization, and Involvement. The MBI was translated into Japanese along with a back-translation and was administered to a sample of 267 nurses. Various psychometric analyses showed that the Japanese version of the MBI has high reliability for the 22 items scored for the frequency dimension. The factor analysis using principal factoring with an oblique rotation resulted in three factor structures that had different implications from the MBI: Emotional Exhaustion/Depersonalization, Personal Accomplishment, and Physical Exhaustion. The correlationship between the MBI and the General Health Questionnaire (GHQ), measures of depression, showed that burnout was a unique phenomenon.

  2. Examining the Factor Structure of the Self-Compassion Scale in Four Distinct Populations: Is the Use of a Total Scale Score Justified?

    Science.gov (United States)

    Neff, Kristin D; Whittaker, Tiffany A; Karl, Anke

    2017-01-31

    This study examined the factor structure of the Self-Compassion Scale (SCS) using a bifactor model, a higher order model, a 6-factor correlated model, a 2-factor correlated model, and a 1-factor model in 4 distinct populations: college undergraduates (N = 222), community adults (N = 1,394), individuals practicing Buddhist meditation (N = 215), and a clinical sample of individuals with a history of recurrent depression (N = 390). The 6-factor correlated model demonstrated the best fit across samples, whereas the 1- and 2-factor models had poor fit. The higher order model also showed relatively poor fit across samples, suggesting it is not representative of the relationship between subscale factors and a general self-compassion factor. The bifactor model, however, had acceptable fit in the student, community, and meditator samples. Although fit was suboptimal in the clinical sample, results suggested an overall self-compassion factor could still be interpreted with some confidence. Moreover, estimates suggested a general self-compassion factor accounted for at least 90% of the reliable variance in SCS scores across samples, and item factor loadings and intercepts were equivalent across samples. Results suggest that a total SCS score can be used as an overall mesure of self-compassion.

  3. Prevalence and Risk Factors of Early-Stage Age-Related Macular Degeneration in Patients Examined at a Health Promotion Center in Korea

    OpenAIRE

    Moon, Byung Gil; Joe, Soo Geun; Hwang, Jong-Uk; Kim, Hong Kyu; Choe, Jaewon; Yoon, Young Hee

    2012-01-01

    We evaluated the prevalence and risk factors for early age-related macular degeneration (AMD) in Koreans 50 yr of age or older who were examined at a single health promotion center. We retrospectively reviewed the records of 10,449 subjects who visited the center over a 6-month period. Fundus photography was performed on all subjects, and systematic risk factor analysis was conducted using a structured questionnaire. All patients (n = 322) were initially diagnosed with drusen or early AMD usi...

  4. Human factors issues and approaches in the spatial layout of a space station control room, including the use of virtual reality as a design analysis tool

    Science.gov (United States)

    Hale, Joseph P., II

    1994-01-01

    Human Factors Engineering support was provided for the 30% design review of the late Space Station Freedom Payload Control Area (PCA). The PCA was to be the payload operations control room, analogous to the Spacelab Payload Operations Control Center (POCC). This effort began with a systematic collection and refinement of the relevant requirements driving the spatial layout of the consoles and PCA. This information was used as input for specialized human factors analytical tools and techniques in the design and design analysis activities. Design concepts and configuration options were developed and reviewed using sketches, 2-D Computer-Aided Design (CAD) drawings, and immersive Virtual Reality (VR) mockups.

  5. Single versus Multiple Suicide Attempts: A Prospective Examination of Psychiatric Factors and Wish to Die/Wish to Live Index

    Science.gov (United States)

    2013-04-18

    individuals have higher levels of known suicide risk factors , e.g., mood disorder diagnoses and higher rates of depression and hopelessness (e.g., Forman et...17 65.4 Obsessive Compulsive Disorder 5 2.7 3 11.5 Panic Disorder 31 16.5 3 11.5 Social Phobia 16 8.5 5 19.2 Specific Phobia 9 4.8 0 0...history of suicide attempt has been identified as a key risk factor for eventual death by suicide. Individuals with multiple suicide attempts present a

  6. A longitudinal qualitative study examining the factors impacting on the ability of persons with T1DM to assimilate the Dose Adjustment for Normal Eating (DAFNE principles into daily living and how these factors change over time

    Directory of Open Access Journals (Sweden)

    White Florence

    2011-08-01

    Full Text Available Abstract Background The literature reveals that structured education programmes, such as DAFNE, result in many positive outcomes for people with Type 1 diabetes including a decrease in HbA1c levels and reductions in hypoglycaemia. While there is evidence that some of these outcomes are maintained we do not know at present what factors are most important over time. The study aim was to identify the key factors impacting on persons with Type 1 diabetes ability to assimilate the Dose Adjustment For Normal Eating (DAFNE DAFNE principles into their daily lives and how these factors change over time. Methods This is a longitudinal descriptive qualitative study. Interviews were undertaken with 40 participants who had attended DAFNE in one of 5 study sites across the Island of Ireland, at 6 weeks, 6 and 12 months after completion of the programme. The interviews lasted from 30 to 60 minutes and were transcribed verbatim. Data were analysed in three ways, a within time analysis, a cross sectional analysis for each participant and a thematic analysis which focused on examining changes over time Results Four themes that influenced participants' ability to assimilate DAFNE into their daily lives over time were identified. These were: embedded knowledge, continued responsive support, enduring motivation and being empowered. Support at the 6 month period was found to be crucial to continued motivation. Conclusions Understanding the factors that influence people's ability to assimilate DAFNE principles over time into their daily lives can help health professionals give focused responsive support that helps people with diabetes become more empowered. Understanding that continued support matters, particularly around 6 months, is important as health professionals can influence good management by providing appropriate support and enhancing motivation. Trial registration ISRCTN79759174

  7. A longitudinal qualitative study examining the factors impacting on the ability of persons with T1DM to assimilate the Dose Adjustment For Normal Eating (DAFNE) principles into daily living and how these factors change over time

    LENUS (Irish Health Repository)

    Casey, Dympna

    2011-08-30

    Abstract Background The literature reveals that structured education programmes, such as DAFNE, result in many positive outcomes for people with Type 1 diabetes including a decrease in HbA1c levels and reductions in hypoglycaemia. While there is evidence that some of these outcomes are maintained we do not know at present what factors are most important over time. The study aim was to identify the key factors impacting on persons with Type 1 diabetes ability to assimilate the Dose Adjustment For Normal Eating (DAFNE) DAFNE principles into their daily lives and how these factors change over time. Methods This is a longitudinal descriptive qualitative study. Interviews were undertaken with 40 participants who had attended DAFNE in one of 5 study sites across the Island of Ireland, at 6 weeks, 6 and 12 months after completion of the programme. The interviews lasted from 30 to 60 minutes and were transcribed verbatim. Data were analysed in three ways, a within time analysis, a cross sectional analysis for each participant and a thematic analysis which focused on examining changes over time Results Four themes that influenced participants\\' ability to assimilate DAFNE into their daily lives over time were identified. These were: embedded knowledge, continued responsive support, enduring motivation and being empowered. Support at the 6 month period was found to be crucial to continued motivation. Conclusions Understanding the factors that influence people\\'s ability to assimilate DAFNE principles over time into their daily lives can help health professionals give focused responsive support that helps people with diabetes become more empowered. Understanding that continued support matters, particularly around 6 months, is important as health professionals can influence good management by providing appropriate support and enhancing motivation. Trial registration ISRCTN79759174

  8. An Examination of Individual Level Factors in Stress and Coping Processes: Perspectives of Chinese International Students in the United States

    Science.gov (United States)

    Yan, Kun; Berliner, David C.

    2011-01-01

    No empirical research has focused solely upon understanding the stress and coping processes of Chinese international students in the United States. This qualitative inquiry examines the individual-level variables that affect the stress-coping process of Chinese international students and how they conceptualize and adapt to their stress at an…

  9. Examining the Effects of Contextual Factors on Students' Educational Outcomes: A Special Focus on Community Colleges

    Science.gov (United States)

    Mercado, Micaela

    2012-01-01

    This dissertation examines the college experience of traditional-age community college students. The objectives of this dissertation are threefold. To explain early exits from higher education, the first manuscript integrates Tinto's interactionalist theory and Coleman's theory of social capital to describe the mechanisms through which…

  10. An Examination of Individual Level Factors in Stress and Coping Processes: Perspectives of Chinese International Students in the United States

    Science.gov (United States)

    Yan, Kun; Berliner, David C.

    2011-01-01

    No empirical research has focused solely upon understanding the stress and coping processes of Chinese international students in the United States. This qualitative inquiry examines the individual-level variables that affect the stress-coping process of Chinese international students and how they conceptualize and adapt to their stress at an…

  11. Examining Factors Influencing Colorectal Cancer Screening of Rural Nebraskans Using Data from Clinics Participating in an Accountable Care Organization: A Study Protocol [v1; ref status: indexed, http://f1000r.es/5me

    Directory of Open Access Journals (Sweden)

    Lufei Young

    2015-07-01

    Full Text Available Background: Although mortality rates of colorectal cancer (CRC can be significantly reduced through increased screening, rural communities are still experiencing lower rates of screening compared to urban counterparts. Understanding and eliminating barriers to cancer screening will decrease cancer burden and lead to substantial gains in quality and quantity of life for rural populations. However, existing studies have shown inconsistent findings and fail to address how contextual and provider-level factors impact CRC screening in addition to individual-level factors.  Purpose: The purpose of the study is to examine multi-level factors related to CRC screening, and providers’ perception of barriers and facilitators of CRC screening in rural patients cared for by accountable care organization (ACO clinics. Methods/Design: This is a convergent mixed method design. For the quantitative component, multiple data sources, such as electronic health records (EHRs, Area Resource File (ARF, and provider survey data, will be used to examine patient-, provider-, clinic-, and county-level factors. About 21,729 rural patients aged between 50 and 75 years who visited the participating ACO clinics in the past 12 months are included in the quantitative analysis. The qualitative methods include semi-structured in-depth interviews with healthcare professionals in selected rural clinics. Both quantitative and qualitative data will be merged for result interpretation. Quantitative data identifies “what” factors influence CRC screening, while qualitative data explores “how” these factors interact with CRC screening. The study setting is 10 ACO clinics located in nine rural Nebraska counties. Discussion: This will be the first study examining multi-level factors related to CRC screening in the new healthcare delivery system (i.e., ACO clinics in rural communities. The study findings will enhance our understanding of how the ACO model, particularly in rural

  12. Interpersonal Perceptions of the Five-Factor Model of Personality: An Examination Using the Structural Summary Method for Circumplex Data

    Science.gov (United States)

    Ansell, Emily B.; Pincus, Aaron L.

    2004-01-01

    Research investigating the structural convergence of the Interpersonal Circumplex (IPC; Wiggins, 1979, 1995) with the Five Factor Model (FFM; Costa & McCrae, 1992) of personality has predominantly focused on the traits of Agreeableness and Extraversion. The characteristics of the other three FFM traits: Neuroticism, Openness, and Conscientiousness…

  13. Student Motivation and the "Feel Good" Factor: An Empirical Examination of Motivational Predictors of University Service Quality Evaluation

    Science.gov (United States)

    Chong, Yit Sean; Ahmed, Pervaiz K.

    2015-01-01

    With the globalisation of the higher education industry, service quality in the higher education services is seen as a vital factor in determining a university's competitive advantage. The purpose of this study is to extend current conceptualisation of quality research in higher education by investigating the influence of self-determination and…

  14. The Effect of College Selection Factors on Persistence: An Examination of Black and Latino Males in the Community College

    Science.gov (United States)

    Wood, J. Luke; Harris, Frank, III

    2015-01-01

    The purpose of this study was to understand the relationship (if any) between college selection factors and persistence for Black and Latino males in the community college. Using data derived from the Educational Longitudinal Study, backwards stepwise logistic regression models were developed for both groups. Findings are contextualized in light…

  15. Factors Associated with General and Sexual Alcohol-Related Consequences: An Examination of College Students Studying Abroad

    Science.gov (United States)

    Hummer, Justin F.; Pedersen, Eric R.; Mirza, Tehniat; LaBrie, Joseph W.

    2010-01-01

    This study contributes to the scarce research on U.S. college students studying abroad by documenting general and sexual negative alcohol-related risks and factors associated with such risk. The manner of drinking (quantity vs. frequency), pre-departure expectations surrounding alcohol use while abroad, culture-related social anxiety, and…

  16. Examination of Factors That Predict Academic Adjustment and Success of Community College Transfer Students in STEM at 4-Year Institutions

    Science.gov (United States)

    Lopez, Carlos; Jones, Stephanie J.

    2017-01-01

    There are a limited number of individuals who possess the skills to fulfill the workforce demand in STEM (science, technology, engineering, and math) in the United States. Therefore, community colleges and 4-year institutions must be able to identify academic and social factors that impact students' participation in the areas of STEM. These…

  17. Critical-Thinking Grudge Match: Biology vs. Chemistry--Examining Factors That Affect Thinking Skill in Nonmajors Science

    Science.gov (United States)

    Quitadamo, Ian J.; Kurtz, Martha J.; Cornell, Caitlyn Nicole; Griffith, Lindsay; Hancock, Julie; Egbert, Brandi

    2011-01-01

    Chemistry students appear to bring significantly higher critical-thinking skill to their nonmajors course than do biology students. Knowing student preconceptions and thinking ability is essential to learning growth and effective teaching. Of the factors investigated, ethnicity and high school physics had the largest impact on critical-thinking…

  18. Student Motivation and the "Feel Good" Factor: An Empirical Examination of Motivational Predictors of University Service Quality Evaluation

    Science.gov (United States)

    Chong, Yit Sean; Ahmed, Pervaiz K.

    2015-01-01

    With the globalisation of the higher education industry, service quality in the higher education services is seen as a vital factor in determining a university's competitive advantage. The purpose of this study is to extend current conceptualisation of quality research in higher education by investigating the influence of self-determination and…

  19. Examination of the predictive factors of the response to whole brain radiotherapy for brain metastases from lung cancer using MRI.

    Science.gov (United States)

    Aoki, Shuri; Kanda, Tomonori; Matsutani, Noriyuki; Seki, Nobuhiko; Kawamura, Masafumi; Furui, Shigeru; Yamashita, Hideomi

    2017-07-01

    Previous studies have been conducted on the prognostic factors for overall survival in patients with brain metastases (BMs) following whole brain radiotherapy (WBRT). However, there have been a small number of studies regarding the prognostic factors for the response of tumor to WBRT. The aim of the present study was to identify the predictive factors for the response to WBRT from the point of view of reduction of tumor using magnetic resonance imaging. A retrospective analysis of 62 patients with BMs from primary lung cancer treated with WBRT was undertaken. The effects of the following factors on the response to WBRT were evaluated: Age; sex; performance status; lactate dehydrogenase; pathology; existence of extracranial metastases; activity of extracranial disease; chemo-history; chest radiotherapy history; treatment term; γ-knife radiotherapy; diffusion weighted image signal intensity; tumor diameter; extent of edema and the edema/tumor (E/T) ratio. The association between the reduction of tumors and clinical factors was evaluated using logistic regression analysis. P<0.05 was considered to indicate a statistically significant difference. The overall response ratio of this cohort was 54.8%. In the univariate analysis, the response of tumors was associated with the presence of small cell lung carcinoma (SCLC; P=0.0007), an E/T ratio of ≥1.5 (P=0.048), and a median tumor diameter of <20 mm (P=0.014). In the multivariate analysis, the presence of SCLC [P=0.001; odds ratio (OR), 17.152), an E/T ratio of ≥1.5 (P=0.019; OR, 9.526), and the presence of extracranial metastases (P=0.031; OR, 4.875) were revealed to be independent predictive factors for the reduction of tumor. The following 3 factors were significantly associated with the response of tumors to WBRT: The presence of SCLC; an E/T ratio of ≥1.5; and the presence of extracranial metastases. The E/T ratio is a novel index that provides a simple and easy predictive method for use in a clinical setting.

  20. Examination of the interrelations between the factors of PTSD, major depression, and generalized anxiety disorder in a heterogeneous trauma-exposed sample using DSM 5 criteria.

    Science.gov (United States)

    Price, Matthew; van Stolk-Cooke, Katherine

    2015-11-01

    Exposure to traumatic events places individuals at high risk for multiple psychiatric disorders, including posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and generalized anxiety disorder (GAD). The high rates of comorbidity among these conditions merit evaluation in order to improve diagnosis and treatment approaches. The current study evaluated the association between PTSD, MDD, and GAD factors as presented in the DSM 5. 602 trauma-exposed individuals who experienced an event that met Criterion A for the DSM 5 PTSD diagnosis were recruited through Amazon.com, Inc.'s Mechanical Turk (MTurk) to complete an assessment of the impact of stressful events on their lives. High interrelations were detected among the 4 PTSD factors, 2 MDD factors that corresponded to somatic and affective symptoms, and the single GAD factor. The affective factor of MDD was most strongly related to the emotional numbing factor of PTSD, whereas the somatic factor of MDD was most strongly related to the hyperarousal factor of PTSD. The GAD factor was most strongly related to the hyperarousal factor of PTSD, relative to the other PTSD factors. The strength of the interrelations between factors of the three disorders is largely a function of the overlap in symptoms and calls into question the uniqueness of negative affective symptoms of PTSD, MDD and GAD. Results suggest that improved understanding of the trauma reaction requires a focus on the unique presentation of each individual and assessment of multiple disorders.

  1. Measuring psychosocial environments using individual responses: an application of multilevel factor analysis to examining students in schools.

    Science.gov (United States)

    Dunn, Erin C; Masyn, Katherine E; Jones, Stephanie M; Subramanian, S V; Koenen, Karestan C

    2015-07-01

    Interest in understanding how psychosocial environments shape youth outcomes has grown considerably. School environments are of particular interest to prevention scientists as many prevention interventions are school-based. Therefore, effective conceptualization and operationalization of the school environment is critical. This paper presents an illustration of an emerging analytic method called multilevel factor analysis (MLFA) that provides an alternative strategy to conceptualize, measure, and model environments. MLFA decomposes the total sample variance-covariance matrix for variables measured at the individual level into within-cluster (e.g., student level) and between-cluster (e.g., school level) matrices and simultaneously models potentially distinct latent factor structures at each level. Using data from 79,362 students from 126 schools in the National Longitudinal Study of Adolescent to Adult Health (formerly known as the National Longitudinal Study of Adolescent Health), we use MLFA to show how 20 items capturing student self-reported behaviors and emotions provide information about both students (within level) and their school environment (between level). We identified four latent factors at the within level: (1) school adjustment, (2) externalizing problems, (3) internalizing problems, and (4) self-esteem. Three factors were identified at the between level: (1) collective school adjustment, (2) psychosocial environment, and (3) collective self-esteem. The finding of different and substantively distinct latent factor structures at each level emphasizes the need for prevention theory and practice to separately consider and measure constructs at each level of analysis. The MLFA method can be applied to other nested relationships, such as youth in neighborhoods, and extended to a multilevel structural equation model to better understand associations between environments and individual outcomes and therefore how to best implement preventive interventions.

  2. A retrospective study using the pressure ulcer scale for healing (PUSH) tool to examine factors affecting stage II pressure ulcer healing in a Korean acute care hospital.

    Science.gov (United States)

    Park, Kyung Hee

    2014-09-01

    Stage II pressure ulcers (PUs) should be managed promptly and appropriately in order to prevent complications. To identify the factors affecting Stage II PU healing and optimize care, the electronic medical records of patients with a Stage II PU in an acute care hospital were examined. Patient and ulcer characteristics as well as nutritional assessment variables were retrieved, and ulcer variables were used to calculate Pressure Ulcer Scale for Healing (PUSH) scores. The effect of all variables on healing status (healed versus nonhealed) and change in PUSH score for healing rate were compared. Records of 309 Stage II PUs from 155 patients (mean age 61.2 ± 15.2 [range 5-89] years, 182 [58.9%] male) were retrieved and analyzed. Of those, 221 healed and 88 were documented as not healed at the end of the study. The variables that were significantly different between patients with PUs that did and did not heal were: major diagnosis (P = 0.001), peripheral arterial disease (P = 0.007), smoking (P = 0.048), serum albumin ( PUSH score change -indicative of healing - when pressure-redistribution surfaces were used (P strategies for healing Stage II PUs in the acute care setting should include early recognition of lower-stage PUs, the provision of static pressure-redistribution surfaces and multivitamins, and maintaining higher MAP may facilitate healing and prevent deterioration. Further prospective research is warranted to verify the effect of these interventions.

  3. Factors limiting the usefulness of histopathologic examination of skin biopsies in the diagnosis of large animal dermatoses.

    Science.gov (United States)

    McGavin, M D; Fadok, V A

    1984-03-01

    Skin biopsy for histologic, immunofluorescent, parasitologic, and bacteriologic examination is a common procedure, but for maximum effectiveness the clinician must realize the importance of precautions to select the correct stage of lesion of different diseases; avoiding creating artifacts during removal and fixation; and give full details of history, clinical diagnosis, and differential diagnoses on the laboratory request sheet. Pathology reports describing the subtleties of histologic changes are difficult to write, particularly if the lesions are not specific. Overly long histologic reports without a definitive diagnosis may frustrate a clinician who is unfamiliar with the significance of histologic lesions. For these reasons, clinician and pathologist must develop a rapport and empathy for the other's difficulties and adequately communicate to allow each to make a maximum contribution toward the final diagnosis. Histopathologic examination of skin lesions may not produce a specific diagnosis but is frequently useful in the elimination of other suspected diagnoses.

  4. Examining factors affecting beginning teachers' transfer of learning of ICT-enhanced learning activities in their teaching practice

    OpenAIRE

    Agyei, D.D.; Voogt, J.

    2014-01-01

    This study examined 100 beginning teachers’ transfer of learning when utilising Information Communication Technology-enhanced activity-based learning activities. The beginning teachers had participated in a professional development program that was characterised by ‘learning technology by collaborative design’ in their final year of their pre-service preparation program. Transfer of learning was proposed as characteristic of (i) the professional development program,(ii) beginning teachers and...

  5. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis

    DEFF Research Database (Denmark)

    Bendtzen, K; Hansen, P R; Rieneck, K

    2003-01-01

    for up to 22 months with 1-3 mg/kg/day. Spironolactone, at in vivo attainable doses, markedly suppressed transcription of several proinflammatory cytokines and, accordingly, inhibited release of tumour necrosis factor, lymphotoxin, interferon-gamma, granulocyte-macrophage colony-stimulating factor....... In conclusion, spironolactone inhibits production of several proinflammatory cytokines considered to be of pathogenic importance in many immunoinflammatory diseases and shows positive effect in patients with chronic arthritis. Its effect as an anti-inflammatory drug should be explored, because prolonged...... and interleukin 6 (70-90% inhibition). Release of these cytokines was also suppressed when testing whole blood from RA patients receiving 50 mg spironolactone twice daily, indicating that pharmaceutical use of the drug may suppress the release of inflammatory cytokines. Spironolactone therapy was generally well...

  6. Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis

    DEFF Research Database (Denmark)

    Bendtzen, K; Hansen, P R; Rieneck, K

    2003-01-01

    ,000 genes) and enzyme immunoassay for quantitating secreted pro- and anti-inflammatory cytokines. Furthermore, to evaluate the safety and efficacy of spironolactone as an anti-inflammatory drug 21 patients with rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA) or other arthritides were treated...... for up to 22 months with 1-3 mg/kg/day. Spironolactone, at in vivo attainable doses, markedly suppressed transcription of several proinflammatory cytokines and, accordingly, inhibited release of tumour necrosis factor, lymphotoxin, interferon-gamma, granulocyte-macrophage colony-stimulating factor...... and interleukin 6 (70-90% inhibition). Release of these cytokines was also suppressed when testing whole blood from RA patients receiving 50 mg spironolactone twice daily, indicating that pharmaceutical use of the drug may suppress the release of inflammatory cytokines. Spironolactone therapy was generally well...

  7. Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti–factor VIII immune responses

    OpenAIRE

    Ettinger, Ruth A.; James, Eddie A.; Kwok, William W.; Arthur R Thompson; Pratt, Kathleen P.

    2009-01-01

    The development of neutralizing antibodies (inhibitors) after factor VIII (FVIII) infusions is a serious complication that affects approximately one-quarter of hemophilia A patients who have access to replacement therapy. To investigate the differentiation of naive T cells into FVIII-specific helper T cells that promote B-cell activation and antibody secretion, HLA-DRA-DRB1*0101-restricted T-cell clones that respond to a specific epitope in FVIII were isolated from a mild hemophilia A subject...

  8. Disease-related and psychosocial factors associated with depressive symptoms in patients with systemic sclerosis, including fear of progression and appearance self-esteem.

    Science.gov (United States)

    Kwakkenbos, Linda; van Lankveld, Wim G J M; Vonk, Madelon C; Becker, Eni S; van den Hoogen, Frank H J; van den Ende, Cornelia H M

    2012-03-01

    The prevalence of depressive symptoms is high in patients with systemic sclerosis (SSc, scleroderma). This study was conducted to determine which disease-related and psychosocial factors are associated with depressive symptoms, independent of sociodemographic factors. In total, 215 patients with SSc completed questionnaires on sociodemographics, physical functioning (HAQ-DI), pain (VAS), fatigue (CIS), psychosocial characteristics (CISS, ICQ, PRQ, ASE, FoP-Q-SF) and depressive symptoms (CES-D). Disease characteristics (disease duration, disease subtype, modified Rodnan Skin Score) were collected. Hierarchical linear regression analyses were conducted to assess associations with depressive symptoms. The mean CES-D score was 12.9 (SD=9.7) and the prevalence of patients scoring>= 16 and>=19 were 32.1% and 25.1%, respectively. The variance explained by sociodemographics and disease characteristics was negligible (R(2)≤.09). Fatigue and pain were independently associated with depressive symptoms (R(2) change=.35). After adding psychological factors (R(2) change=.21), satisfaction with social support, emotion-focused coping and helplessness were also significantly associated with depressive symptoms. Higher fear of progression was associated with more depressive symptoms (P≤.01), and appearance self-esteem showed a marginally significant association (P=.08). Depressive symptoms were common in the present sample of patients with SSc and were independently associated with pain, fatigue, social support, emotion-focused coping, helplessness and fear of progression. Results suggest that, in addition to assessment of disease characteristics, attention should be given also to psychosocial factors found to be associated with depressive symptoms. For the development and trialling of psychological interventions, fear of progression could be an important target. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Examining Factors of Acculturative Stress on International Students as They Affect Utilization of Campus-Based Health and Counseling Services at Four-Year Public Universities in Ohio

    Science.gov (United States)

    Hofmann, Paul N.

    2010-01-01

    This study examined factors of acculturative stress experienced by international students as they affect utilization of campus-based health and counseling services. Eight hundred thirty-eight international students studying at 11 four-year public institutions in the State of Ohio were surveyed to determine how frequently they had experienced 20…

  10. What are patient factors associated with the quality of diabetes care?: results from the Korean National Health and Nutrition Examination Survey

    Science.gov (United States)

    2012-01-01

    Background Recently there has been a growing interest in healthcare quality control in Korea. We examined the association between patient factors and quality indicators of diabetic care among Korean adults with diabetes. Methods We obtained a sample of 335 adults aged 20 or older diagnosed with diabetes from the 2005 Korean National Health and Nutrition Examination Survey. Patient factors were divided into two categories: socioeconomic position and health-related factors. Quality indicators for diabetes care were defined as receiving preventive care services for diabetes complications (e.g., fundus examination, microalbuminuria examination, diabetes education) and diabetes-related clinical outcomes (e.g., HbA1c, blood pressure, LDL-cholesterol). We performed multiple logistic regression analyses for each quality indicator. Results We found that people with lower education levels or shorter duration of diabetes illness were less likely to receive preventive care services for diabetes complications. Women or people with longer duration of diabetes were less likely to reach the glycemic target. Obese diabetic patients were less likely to accomplish adequate control of blood pressure and LDL-cholesterol. Conclusions Several factors of patients with diabetes, such as education level, duration of illness, gender, and obesity grade are associated with the quality of diabetes care. These findings can help inform policy makers about subpopulations at risk in developing a public health strategy in the future. PMID:22913274

  11. Examining Factors of Acculturative Stress on International Students as They Affect Utilization of Campus-Based Health and Counseling Services at Four-Year Public Universities in Ohio

    Science.gov (United States)

    Hofmann, Paul N.

    2010-01-01

    This study examined factors of acculturative stress experienced by international students as they affect utilization of campus-based health and counseling services. Eight hundred thirty-eight international students studying at 11 four-year public institutions in the State of Ohio were surveyed to determine how frequently they had experienced 20…

  12. A Cross-Cultural Examination of the Impact of Social, Organisational and Individual Factors on Educational Technology Acceptance between British and Lebanese University Students

    Science.gov (United States)

    Tarhini, Ali; Hone, Kate; Liu, Xiaohui

    2015-01-01

    This paper examines the social, organisational and individual factors that may affect students' acceptance of e-learning systems in higher education in a cross-cultural context. A questionnaire was developed based on an extended technology acceptance model (TAM). A total sample of 1173 university students from two private universities in Lebanon…

  13. What are patient factors associated with the quality of diabetes care?: results from the Korean National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Ko Ki

    2012-08-01

    Full Text Available Abstract Background Recently there has been a growing interest in healthcare quality control in Korea. We examined the association between patient factors and quality indicators of diabetic care among Korean adults with diabetes. Methods We obtained a sample of 335 adults aged 20 or older diagnosed with diabetes from the 2005 Korean National Health and Nutrition Examination Survey. Patient factors were divided into two categories: socioeconomic position and health-related factors. Quality indicators for diabetes care were defined as receiving preventive care services for diabetes complications (e.g., fundus examination, microalbuminuria examination, diabetes education and diabetes-related clinical outcomes (e.g., HbA1c, blood pressure, LDL-cholesterol. We performed multiple logistic regression analyses for each quality indicator. Results We found that people with lower education levels or shorter duration of diabetes illness were less likely to receive preventive care services for diabetes complications. Women or people with longer duration of diabetes were less likely to reach the glycemic target. Obese diabetic patients were less likely to accomplish adequate control of blood pressure and LDL-cholesterol. Conclusions Several factors of patients with diabetes, such as education level, duration of illness, gender, and obesity grade are associated with the quality of diabetes care. These findings can help inform policy makers about subpopulations at risk in developing a public health strategy in the future.

  14. Examining the Diet of Post-Migrant Hispanic Males Using the Precede-Proceed Model: Predisposing, Reinforcing, and Enabling Dietary Factors

    Science.gov (United States)

    Castellanos, Diana Cuy; Downey, Laura; Graham-Kresge, Susan; Yadrick, Kathleen; Zoellner, Jamie; Connell, Carol L.

    2013-01-01

    Objective: To examine socio-environmental, behavioral, and predisposing, reinforcing, and enabling (PRE) factors contributing to post-migration dietary behavior change among a sample of traditional Hispanic males. Design: In this descriptive study, semistructured interviews, a group interview, and photovoice, followed by group interviews, were…

  15. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer.

    LENUS (Irish Health Repository)

    Cathcart, Mary-Clare

    2011-03-01

    Thromboxane synthase (TXS) metabolises prostaglandin H2 into thromboxanes, which are biologically active on cancer cells. TXS over-expression has been reported in a range of cancers, and associated with a poor prognosis. TXS inhibition induces cell death in-vitro, providing a rationale for therapeutic intervention. We aimed to determine the expression profile of TXS in NSCLC and if it is prognostic and\\/or a survival factor in the disease.

  16. Childhood ADHD and Adolescent Substance Use: An Examination of Deviant Peer Group Affiliation as a Risk Factor

    OpenAIRE

    Marshal, Michael P.; Molina, Brooke S.G.; Pelham, William E.

    2003-01-01

    Deviant peer group affiliation was evaluated as a risk factor for substance use in adolescents with childhood attention-deficit/hyperactivity disorder (ADHD). Results showed that deviant peer affiliation mediated the relationship between ADHD and substance use, suggesting that children with ADHD are more likely than children without ADHD to become involved with deviant peers and, as a result, more likely to use substances. Moreover, the relationship between deviant peer affiliation and substa...

  17. Prevalence and Factors Associated with the Use of Eye Care Services in South Korea: Korea National Health and Nutrition Examination Survey 2010–2012

    Science.gov (United States)

    Park, Yong Seok; Heo, Hwan; Ye, Byeong Jin; Suh, Young-Woo; Kim, Seung-Hyun; Park, Shin Hae; Lim, Key Hwan; Lee, Sung Jin; Park, Song Hee

    2017-01-01

    Purpose To estimate the factors and prevalence of eye care service utilization in the South Korean population. Methods This cross-sectional, population-based study included data from 22,550 Koreans aged ≥5 years who participated in the Korea National Health and Nutrition Examination Survey from 2010 to 2012. For people aged 5 to 11 years (young children), information was based on self-reports of contact with eye care service in the past year; for people aged ≥12 years (older population), the information was based on the self-reported lifetime contact with eye care service. Univariate and multivariate logistic regression analyses of the complex sample survey data were performed. Results The prevalence of eye care service use in young children during the past year was 61.1% (95% confidence interval, 58.1%–64.1%), while that in the older population during their lifetime was 73.5%. Subjects aged 7 to 11 years were more likely to have had an eye examination in the past year than subjects aged 5 to 6 years (odds ratio, 3.83; 95% confidence interval, 2.37–6.19). Multivariate logistic regression analysis indicated that higher monthly household income, being a National Health Insurance holder, and having private health insurance were related to more frequent use of eye care services in young children. For the older population and women, those living in an urban area and those with a best-corrected visual acuity less than 20 / 40 in the worse-seeing eye were more likely to have had an eye examination during their lifetime. Low education level was associated with low lifetime use of eye care services in the older population. Conclusions There are sociodemographic disparities with use of eye care services in South Korea. This population-based study provides information that is useful for determining different intervention programs based on sociodemographic disparities to promote eye care service utilization in South Korea. PMID:28243025

  18. Examination of the relationship between project management critical success factors and project success of oil and gas drilling projects

    Science.gov (United States)

    Alagba, Tonye J.

    Oil and gas drilling projects are the primary means by which oil companies recover large volumes of commercially available hydrocarbons from deep reservoirs. These types of projects are complex in nature, involving management of multiple stakeholder interfaces, multidisciplinary personnel, complex contractor relationships, and turbulent environmental and market conditions, necessitating the application of proven project management best practices and critical success factors (CSFs) to achieve success. Although there is some practitioner oriented literature on project management CSFs for drilling projects, none of these is based on empirical evidence, from research. In addition, the literature has reported alarming rates of oil and gas drilling project failure, which is attributable not to technical factors, but to failure of project management. The aim of this quantitative correlational study therefore, was to discover an empirically verified list of project management CSFs, which consistent application leads to successful implementation of oil and gas drilling projects. The study collected survey data online, from a random sample of 127 oil and gas drilling personnel who were members of LinkedIn's online community "Drilling Supervisors, Managers, and Engineers". The results of the study indicated that 10 project management factors are individually related to project success of oil and gas drilling projects. These 10 CSFs are namely; Project mission, Top management support, Project schedule/plan, Client consultation, Personnel, Technical tasks, Client acceptance, Monitoring and feedback, Communication, and Troubleshooting. In addition, the study found that the relationships between the 10 CSFs and drilling project success is unaffected by participant and project demographics---role of project personnel, and project location. The significance of these findings are both practical, and theoretical. Practically, application of an empirically verified CSFs list to oil

  19. Factors associated with early adoption of the HPV vaccine in US male adolescents include Hispanic ethnicity and receipt of other vaccines

    Directory of Open Access Journals (Sweden)

    Deanna Kepka

    2016-12-01

    Full Text Available Adolescent males' HPV vaccine initiation and completion in the United States is far below the Healthy People 2020 goal of 80% 3-dose completion among boys. In 2012, less than 7% of males ages 13–17 years had completed the 3-dose series. The Diffusion of Innovations framework guided this investigation of factors related to early adoption of HPV vaccination among male adolescents. Provider-validated data from the 2012 National Immunization Survey-Teen (NIS-Teen for male adolescents ages 13–17 years were analyzed via a multivariable Poisson regression to estimate prevalence ratios for factors associated with HPV vaccine initiation and completion. Adolescent males who are Hispanic and those who are up to date on other recommended adolescent vaccinations were most likely to complete the HPV vaccine. Public health interventions are needed to improve low HPV vaccination rates among adolescent males in the United States. Description of early adopters of the HPV vaccine provides historical context of HPV vaccination acceptance that is needed to inform the design of targeted vaccination interventions to prevent negative HPV-associated outcomes.

  20. Factors associated with early adoption of the HPV vaccine in US male adolescents include Hispanic ethnicity and receipt of other vaccines.

    Science.gov (United States)

    Kepka, Deanna; Ding, Qian; Hawkins, Amy J; Warner, Echo L; Boucher, Kenneth M

    2016-12-01

    Adolescent males' HPV vaccine initiation and completion in the United States is far below the Healthy People 2020 goal of 80% 3-dose completion among boys. In 2012, less than 7% of males ages 13-17 years had completed the 3-dose series. The Diffusion of Innovations framework guided this investigation of factors related to early adoption of HPV vaccination among male adolescents. Provider-validated data from the 2012 National Immunization Survey-Teen (NIS-Teen) for male adolescents ages 13-17 years were analyzed via a multivariable Poisson regression to estimate prevalence ratios for factors associated with HPV vaccine initiation and completion. Adolescent males who are Hispanic and those who are up to date on other recommended adolescent vaccinations were most likely to complete the HPV vaccine. Public health interventions are needed to improve low HPV vaccination rates among adolescent males in the United States. Description of early adopters of the HPV vaccine provides historical context of HPV vaccination acceptance that is needed to inform the design of targeted vaccination interventions to prevent negative HPV-associated outcomes.

  1. Examining social competence, self-perception, quality of life, and internalizing and externalizing symptoms in adolescent females with and without autism spectrum disorder: a quantitative design including between-groups and correlational analyses.

    Science.gov (United States)

    Jamison, T Rene; Schuttler, Jessica Oeth

    2015-01-01

    Adolescent females with an autism spectrum disorder (ASD) are an understudied population, yet are also quite vulnerable, due to the increased complexities of social interaction and increased risk for internalizing symptoms in adolescence. Most research literature currently focuses on males with ASD, limiting our understanding of social experiences for females with ASD, and thus the potential to better inform supports and intervention to promote social-emotional functioning. This study examined similarities and differences in selected indicators of social-emotional health (social competence, self-perception, quality of life) and problematic behaviors such as externalizing and internalizing symptoms for adolescent females with and without ASD. This study employed a quantitative design utilizing correlational analysis as well as t test comparisons to examine selected indicators of social-emotional health and problematic symptoms using the Social Skills Improvement System (SSIS), Youth Quality of Life Instrument (YQOL), and the Self-Perceptions Profile for Adolescents (SPPA) for adolescent females with ASD in relation to their typically developing peers. Significant differences were found between females with and without ASD in terms of their self-ratings of social-emotional health and problematic behaviors. The no-ASD group rated themselves higher across all areas of social-emotional health. Findings also suggest strong relationships between these constructs, especially for females without ASD. Parent reports of autism symptoms and social-emotional health indicated that as symptoms of autism are more severe, so too was the impact on individuals' social competence. Adolescent females with ASD perceive themselves as having lower social competence, self-worth, and quality of life and higher levels of internalizing and externalizing symptoms as compared to their typically developing peers. Parent ratings indicate that higher levels of autism symptoms relate to lower

  2. Predicting multiple victim versus single victim sexual abuse: an examination of distal factors and proximal factors associated with the first abuse incident

    OpenAIRE

    McKillop, N.; Smallbone, S.; WORTLEY, R.

    2016-01-01

    Official and confidential self-report data on 83 convicted adult male sexual abusers were analysed to examine whether sexual offending progression can be better predicted from distal antecedents, or from proximal antecedents and outcomes associated with the first sexual abuse incident. Fifty-six offenders who sexually abused more than one victim (multiple victim offenders; MVOs) were compared to 27 offenders who sexually abused a single victim only (single victim offenders; SVOs). MVOs were y...

  3. Cross-cultural examination of the five-factor model of drinking motives in Spanish and Canadian undergraduates

    NARCIS (Netherlands)

    Mezquita, L.; Stewart, S.H.; Kuntsche, E.N.; Grant, V.V.

    2016-01-01

    This study aims to test the cross-cultural suitability of Modified Drinking Motives Questionnaire-Revised (M DMQ-R) (Grant, Stewart, O'Connor, Blackwell, & Conrod, 2007). The sample included 571 Spanish and 571 Canadian undergraduates between the ages of 18 and 22 (65.8% women). The confirmatory fac

  4. Cross-cultural examination of the five-factor model of drinking motives in Spanish and Canadian undergraduates

    NARCIS (Netherlands)

    Mezquita, L.; Stewart, S.H.; Kuntsche, E.N.; Grant, V.V.

    2016-01-01

    This study aims to test the cross-cultural suitability of Modified Drinking Motives Questionnaire-Revised (M DMQ-R) (Grant, Stewart, O'Connor, Blackwell, & Conrod, 2007). The sample included 571 Spanish and 571 Canadian undergraduates between the ages of 18 and 22 (65.8% women). The confirmatory fac

  5. Examining risk and resilience factors for depression: The role of self-criticism and self-compassion.

    Science.gov (United States)

    Ehret, Anna M; Joormann, Jutta; Berking, Matthias

    2015-01-01

    Whereas self-criticism has been proposed as an important risk factor for major depressive disorder (MDD), self-compassion has been suggested as a resilience factor that protects against the development and maintenance of depressive episodes. This study aimed to test the hypothesis that frequent self-criticism and low habitual self-compassion are related to concurrent depression and to vulnerability to depression by comparing groups of currently, remitted and never depressed individuals. As expected, both currently and remitted depressed individuals reported higher levels of self-criticism and lower self-compassion than never depressed controls. Individual differences in self-criticism and self-compassion were related to depression status above and beyond additional potential correlates of MDD (i.e., perfectionistic beliefs and cognitions, rumination and overall adaptive emotion regulation). The findings provide support for the idea that increased self-criticism and decreased self-compassion place certain individuals at increased risk for experiencing depression repeatedly or chronically over the course of their lives.

  6. Factors Influencing Academic Performance Of Standard Eight Girls In National Examinations In Public Primary Schools A Case Of Matungu Division.

    Directory of Open Access Journals (Sweden)

    Oparanya Wamukoya Windrick

    2015-06-01

    Full Text Available ABSTARCT This study is designed to establish the factors influencing academic of standard eight girls in public primary schools in National exams in Matungu division. The researcher aimed at finding out why there is increased low performance of girls in public schools despite the fact that they are assessed through periodic performance tests do continuous assessment tests CATS midterm carry out tuition and the provision of free primary education which is aimed at improving academic performance. This study adapted a descriptive survey design as a major method of research where data was collected by the researcher members of a population under study. The target population comprised of Head teachers teachers pupils parents and parent schools representatives. Purposive sampling and simple random technique were used. Data was collected by use of questionnaires and interview guides. Data was analyzed by use of descriptive statistics constituting frequencies and percentages.The study established that girls were exposed to harsh school environmental conditions they walked long distances to school schools lacked facilities like toilets libraries and were exposed to male pest teachers. There were also teacher factors like training teacher shortage and motivation that affected girls performance.The study came up with recommendations for improvement of girls academic performance. More public schools should be build to reduce on distance and also overpopulation. The ministry of Education should monitor and evaluate the academic performance of girls in rural areas. The government should put up strict rules on pest teachers. The ministry should hire more teachers.

  7. Using a latent variable model with non-constant factor loadings to examine PM2.5 constituents related to secondary inorganic aerosols.

    Science.gov (United States)

    Zhang, Zhenzhen; O'Neill, Marie S; Sánchez, Brisa N

    2016-04-01

    Factor analysis is a commonly used method of modelling correlated multivariate exposure data. Typically, the measurement model is assumed to have constant factor loadings. However, from our preliminary analyses of the Environmental Protection Agency's (EPA's) PM2.5 fine speciation data, we have observed that the factor loadings for four constituents change considerably in stratified analyses. Since invariance of factor loadings is a prerequisite for valid comparison of the underlying latent variables, we propose a factor model that includes non-constant factor loadings that change over time and space using P-spline penalized with the generalized cross-validation (GCV) criterion. The model is implemented using the Expectation-Maximization (EM) algorithm and we select the multiple spline smoothing parameters by minimizing the GCV criterion with Newton's method during each iteration of the EM algorithm. The algorithm is applied to a one-factor model that includes four constituents. Through bootstrap confidence bands, we find that the factor loading for total nitrate changes across seasons and geographic regions.

  8. Does Depth Matter Examining Factors that Could Influence the Acoustic Identification of Odontocete Species on Bottom Moored Recorders

    Science.gov (United States)

    2015-09-30

    vertical array composed of four second-generation Ecological Acoustic Recorders (EAR2s) spaced 90 m apart (Fig. 1). The array will also include a RJE...test both arrays. On August 3rd , the 300 m bottom-moored array was deployed approximately 3 nautical miles south of Lanai in waters 355 m deep. A...100 pinger on the array is variable. Figure 2 – GPS locations of survey vessel between August 3rd -12th recorded every 30 minutes 7

  9. Examination of alternate codon bias solutions for expression and purification of recombinant mechano-growth factor in Escherichia coli.

    Science.gov (United States)

    Feng, Jianguo; Wan, Rongxue; Yi, Qian; He, Ling; Yang, Li; Tang, Liling

    2015-01-01

    Mechano-growth factor (MGF), an alternative splicing variant of insulin-like growth factor-1 (IGF-1) gene, promotes cell proliferation and inhibits cell differentiation. It also plays an important role in tumor development. It is important to optimize the production process and achieve MGF protein because there is no commercial MGF protein available. In this study, the human MGF gene is cloned into pGEX-4T-1 and the recombinant human MGF (rhMGF) protein could be expressed in Rosetta (DE3) by isopropyl β-D-1-thiogalactopyranoside induction but not in BL21 (DE3). Mutation from rare codons to Escherichia coli preferred ones is performed. We obtain MGF(Mut54-56) and MGF(Mut-total) fragments through site-directed mutagenesis and overlapping PCR. Both pGEX-4T-1/MGF(Mut54-56)- and pGEX-4T-1/MGF(Mut-total)-transformed BL21 (DE3) can be induced to express rhMGF protein. To optimize the production technology, expression and purification of rhMGF are analyzed and compared in Rosetta (DE3) and BL21 (DE3). Results indicate that rhMGF expression in BL21 (DE3) is significantly higher than that in Rosetta (DE3). The protein yield of pGEX-4T-1/MGF(Mut-total) in BL21 (DE3) is higher than that of pGEX-4T-1/MGF(Mut54-56). We test the biological activity of MGF protein purified by affinity chromatography in C2C12 cell line and find that rhMGF promotes cell proliferation significantly. In conclusion, we establish a method to produce rhMGF economically with high biological activity in BL21 (DE3).

  10. Potential ecological footprints of active pharmaceutical ingredients: an examination of risk factors in low-, middle- and high-income countries.

    Science.gov (United States)

    Kookana, Rai S; Williams, Mike; Boxall, Alistair B A; Larsson, D G Joakim; Gaw, Sally; Choi, Kyungho; Yamamoto, Hiroshi; Thatikonda, Shashidhar; Zhu, Yong-Guan; Carriquiriborde, Pedro

    2014-11-19

    Active pharmaceutical ingredients (APIs) can enter the natural environment during manufacture, use and/or disposal, and consequently public concern about their potential adverse impacts in the environment is growing. Despite the bulk of the human population living in Asia and Africa (mostly in low- or middle-income countries), limited work relating to research, development and regulations on APIs in the environment have so far been conducted in these regions. Also, the API manufacturing sector is gradually shifting to countries with lower production costs. This paper focuses mainly on APIs for human consumption and highlights key differences between the low-, middle- and high-income countries, covering factors such as population and demographics, manufacture, prescriptions, treatment, disposal and reuse of waste and wastewater. The striking differences in populations (both human and animal), urbanization, sewer connectivity and other factors have revealed that the environmental compartments receiving the bulk of API residues differ markedly between low- and high-income countries. High sewer connectivity in developed countries allows capture and treatment of the waste stream (point-source). However, in many low- or middle-income countries, sewerage connectivity is generally low and in some areas waste is collected predominantly in septic systems. Consequently, the diffuse-source impact, such as on groundwater from leaking septic systems or on land due to disposal of raw sewage or septage, may be of greater concern. A screening level assessment of potential burdens of APIs in urban and rural environments of countries representing low- and middle-income as well as high-income has been made. Implications for ecological risks of APIs used by humans in lower income countries are discussed. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  11. Analysis of Factors Affecting the Quality of Clinical Microbiological Examination%临床微生物检验质量影响因素分析

    Institute of Scientific and Technical Information of China (English)

    时芳芳

    2015-01-01

    ObjectiveTo analyze the main influencing factors of the quality of clinical microbiological examination,and to propose the corresponding countermeasures.Methods The factors affecting the quality of microbiological examination were analyzed from four aspects:the quality of the specimen,the human factor,the operation standard and other factors.ResultsThe clinical microbiological examination should be colected and transported samples,improve the quality of personnel,standard test operation method,strengthen the laboratory other quality control,improve the quality of inspection.ConclusionThere are many factors that affect the quality of clinical microbiological examination,the need to strengthen the attention,from the fundamental measures to improve the level of inspection and quality.%目的:分析临床微生物检验质量的主要影响因素,并提出相应对策。方法从标本质量、人员因素、操作规范及其他因素四方面分析微生物检验质量影响因素,总结质控对策。结果临床微生物检验应正确采集和运送标本,全面提高人员素质,规范检验操作方法,加强实验室其他质控,提高检验质量。结论影响临床微生物检验质量的因素较多,需加强重视,从根本采取措施,提高检验水平与质量。

  12. Latino Adolescents’ Perceived Discrimination in Online and Offline Settings: An Examination of Cultural Risk and Protective Factors

    Science.gov (United States)

    Umaña-Taylor, Adriana J.; Tynes, Brendesha M.; Toomey, Russell B.; Williams, David R.; Mitchell, Kimberly J.

    2015-01-01

    Guided by a risk and resilience framework, the current study examined the associations between Latino adolescents’ (n = 219; Mage 14.35; SD = 1.75) perceptions of ethnic discrimination in multiple settings (e.g., online, school) and several domains of adjustment (e.g., mental health, academic), and tested whether developmentally salient cultural assets (i.e., ethnic identity) directly promoted youth adjustment or moderated the negative impact of discrimination on adjustment. Each of the 3 ethnic identity components (i.e., exploration, resolution, affirmation) demonstrated evidence of promoting positive outcomes among Latino youth; furthermore, there was some evidence that the promotive effects of affirmation and resolution were significantly stronger for older versus younger adolescents. In addition, with the exception of experiences with discrimination from adults outside of the school setting, there was evidence of ethnic identity interacting with each type of discrimination to predict Latino adolescents’ self-esteem, depressive symptoms, and externalizing problems. Findings suggest directions for future research and identify potential targets for intervention that may prove fruitful in programming efforts with Latino adolescents. PMID:25546597

  13. Examining the psychological factors associated with involvement in fantasy sports: An analysis of participants’ motivations and constraints

    Directory of Open Access Journals (Sweden)

    Young Ik Suh

    2010-06-01

    Full Text Available This study examined how fantasy sport participants’ motives and constraints influence their attitudes toward fantasy sports participation. Furthermore, the study attempted to develop a reliable and valid model through which researchers can measure fantasy sports participation-related motivations and constraints. The proposed model for motivations consisted of 21 items with seven dimensions (i.e., economic, social interaction, escape, fantasy, achievement, knowledge, and pass time and the model for constraints consisted of 15 items with five dimensions (i.e., time, accessibility, lack of interest, lack of partners, and lack of knowledge for fantasy sports participants. The Structural Equation Modeling (SEM method with a convenience sample of 161 participants was employed to analyze the conceptual framework and psychometric property of the scale. Motivations for fantasy sports participants were positively and significantly related to and constraints for fantasy sports participants were negatively and significantly related to their attitude toward fantasy sports participation. These results and future implications for practical and theoretical research are also discussed.

  14. Real-world Experience with Sofosbuvir-based Regimens for Chronic Hepatitis C, Including Patients with Factors Previously Associated with Inferior Treatment Response.

    Science.gov (United States)

    Wu, Christina J; Roytman, Marina M; Hong, Leena K; Huddleston, Leslie; Trujillo, Ruby; Cheung, Alvin; Poerzgen, Peter; Tsai, Naoky C S

    2015-09-01

    The introduction of sofosbuvir, a direct acting antiviral, has revolutionized the treatment of chronic hepatitis C virus (HCV). Phase 3 clinical trials have demonstrated the efficacy, simplicity, and tolerability of sofosbuvir-based regimens and report high rates of sustained virological response (SVR) rates. The purpose of this study was to assess whether clinical trial findings translate into a real-world setting, particularly with treatment of chronic HCV in our diverse, multiethnic population of Hawai'i. Retrospective analysis was performed for 113 patients with genotype 1-6 HCV infection being treated at the Queen's Liver Center between January 2014 and March 2015. SVR rates for our cohort were slightly lower than the rates published by the clinical trials. Data analysis also suggested that most baseline characteristics previously associated with inferior response might not be as significant for sofosbuvir-based regimens; in our cohort, male gender was the only factor significantly related to increased risk of virologic relapse. Pacific Islanders also had higher rate of relapse compared to other ethnic groups, but the small number of patients treated in this subgroup make it difficult to validate this finding. While newer all-oral treatment regimens have been introduced since this study, we highlight the importance of comparing real-world versus clinical trial results for new treatments, and provide data analyses for treatment of chronic HCV in Hawai'i.

  15. Examination of the regulatory frameworks applicable to biologic drugs (including stem cells and their progeny) in Europe, the U.S., and Australia: part I--a method of manual documentary analysis.

    Science.gov (United States)

    Ilic, Nina; Savic, Snezana; Siegel, Evan; Atkinson, Kerry; Tasic, Ljiljana

    2012-12-01

    Recent development of a wide range of regulatory standards applicable to production and use of tissues, cells, and other biologics (or biologicals), as advanced therapies, indicates considerable interest in the regulation of these products. The objective of this study was to analyze and compare high-tier documents within the Australian, European, and U.S. biologic drug regulatory environments using qualitative methodology. Cohort 1 of the selected 18 high-tier regulatory documents from the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA), and the Therapeutic Goods Administration (TGA) regulatory frameworks were subject to a manual documentary analysis. These documents were consistent with the legal requirements for manufacturing and use of biologic drugs in humans and fall into six different categories. Manual analysis included a terminology search. The occurrence, frequency, and interchangeable use of different terms and phrases were recorded in the manual documentary analysis. Despite obvious differences, manual documentary analysis revealed certain consistency in use of terminology across analyzed frameworks. Phrase search frequencies have shown less uniformity than the search of terms. Overall, the EMA framework's documents referred to "medicinal products" and "marketing authorization(s)," the FDA documents discussed "drug(s)" or "biologic(s)," and the TGA documents referred to "biological(s)." Although high-tier documents often use different terminology they share concepts and themes. Documents originating from the same source have more conjunction in their terminology although they belong to different frameworks (i.e., Good Clinical Practice requirements based on the Declaration of Helsinki, 1964). Automated (software-based) documentary analysis should be obtained for the conceptual and relational analysis.

  16. Evaluating the prevalence of canceling surgical operations,including its influencing factors at Imam Khomeini hospital in Sari during 2006-2007

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    A. Zamani kiasari

    2008-01-01

    Full Text Available AbstractBackground and Purpose: Hospital admission for surgery is an important event for patients. Canceling surgical procedures produce several unpleasant results for patients such as waste of time, including payment. The aim of this study is to identify the prevalence and causes of canceling surgical procedures, in order to achieve problem solving methods.Materials and Methods: This is a descriptive cross-sectional study. Statistical data regarding all surgical procedures (without sampling performed during 2006 to 2007, were recorded in a checklist. Study variables were identified based on surgical procedures that were canceled during this study. Data was analyzed using SPSS software and statistical analysis tests.Results: Of 4,711 scheduled patients, 510 (10/9% surgical operations were canceled. The highest number of patient candidates for surgical operation was related to gynecology, orthopedic, urology, while the least were related to reconstructive and vascular surgery groups respectively. The most canceled surgical procedures were related to neurosurgical operation 32/4% (68 from 207 cases while the least canceled cases belonged to gynecology 4/4% (48 from 1094 cases.Conclusion: The results of our study showed that 54/2% of canceled cases were preventable. The results of this study and similar studies demonstrate that traditional pre-operative preparation for surgical scheduling, day before surgery is in need of serious consideration. We recommend a fundamental change by discarding traditional methods and creating a new committee including specialized bed or resource groups, monthly management meetings to discuss causes of canceling surgical procedures, in order to reduce its occurrence. Thus, decreasing the rate of canceling surgical wasted, while reducing anxiety in patients and their family. J Mazand Univ Med Sci 2008; 18(65:52-62 (Persian

  17. Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD

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    Chim Chor

    2012-06-01

    Full Text Available Abstract Background We have reported promising outcomes using a staged approach, in which bortezomib/thalidomide/dexamethasone was used only in 14 patients with suboptimal response to VAD (vincristine/adriamycin/dexamethasone before autologous stem cell transplantation (ASCT. Here we compared the outcomes of the staged approach with frontline PAD (bortezomib/doxorubicin/dexamethasone or VTD (bortezomib/thalidomide/dexamethasone induction, and analysed prognostic factors for outcome. Patients and methods Ninety-one transplant-eligible Chinese patients received three induction regimens prior to ASCT [staged approach (N = 25, PAD (N = 31, VTD (N = 35]. and received thalidomide maintenance for 2 years post-ASCT. Results 43 (47.3% patients had International Staging System (ISS III disease. By an intention-to-treat analysis, the overall CR/nCR rate were 37.4% post-induction, and 62.6% post-ASCT. Five-year overall (OS and event-free (EFS survivals were 66% and 45.1%. There was no difference of the post-induction CR/nCR rate, EFS or OS between patients induced by these three regimens. Moreover, ISS III disease did not affect CR/nCR rates. Multivariate analysis showed that ISS and post-ASCT CR/nCR impacted OS while ISS and post-induction CR/nCR impacted EFS. Conclusions These three induction regimens produced comparable and favorable outcomes in myeloma. The unfavorable outcome of ISS stage III persisted despite upfront/early use of bortezomib. CR/nCR predicted favorable survivals.

  18. Borrelidin Isolated from Streptomyces sp. Inhibited Adipocyte Differentiation in 3T3-L1 Cells via Several Factors Including GATA-Binding Protein 3.

    Science.gov (United States)

    Matsuo, Hirotaka; Kondo, Yoshiyuki; Kawasaki, Takashi; Tokuyama, Shinji; Imamura, Nobutaka

    2015-01-01

    An inhibitor of 3T3-L1 adipocyte differentiation was isolated from Streptomyces sp. TK08330 and identified by spectroscopy as the 18-membered macrolide borrelidin. Treatment with 1.0 μM borrelidin suppressed intracellular lipid accumulation by 80% and inhibited the expression of adipocyte-specific genes. Borrelidin suppressed the mRNA expression of two master regulators of adipocyte differentiation, peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer binding protein (C/EBPα). Studies on well-known upstream regulators of PPARγ revealed that borrelidin down-regulated C/EBPδ mRNA expression but did not affect expression of C/EBPβ. Borrelidin increased mRNA expression of negative regulators of differentiation such as GATA-binding protein (GATA) 3, Krüppel-like factor (KLF) 3 and KLF7, as well as positive regulators, KLF4, KLF6 and KLF15, at early stages of differentiation. To elucidate a primary mediator of borrelidin differentiation inhibitory activity, small interfering RNA (siRNA) transfection experiments were performed. The mRNA expression of PPARγ, which was down-regulated by borrelidin, was not changed by KLF3 and KLF7 siRNA treatment. In contrast, expression of PPARγ in GATA-3 siRNA-treated cells was not significantly different from that of control siRNA-treated cells. Borrelidin significantly inhibited lipid accumulation in control siRNA-treated cells, and treatment with GATA-3 siRNA slightly reduced the inhibitory effect of borrelidin. These results indicate that borrelidin inhibited adipocyte differentiation partially via GATA-3.

  19. Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG mice.

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    Adam C Drake

    Full Text Available Increasing demand for human hematopoietic stem cells (HSCs in clinical and research applications necessitates expansion of HSCs in vitro. Before these cells can be used they must be carefully evaluated to assess their stem cell activity. Here, we expanded cord blood CD34(+ CD133(+ cells in a defined medium containing angiopoietin like 5 and insulin-like growth factor binding protein 2 and evaluated the cells for stem cell activity in NOD-SCID Il2rg(-/- (NSG mice by multi-lineage engraftment, long term reconstitution, limiting dilution and serial reconstitution. The phenotype of expanded cells was characterized by flow cytometry during the course of expansion and following engraftment in mice. We show that the SCID repopulating activity resides in the CD34(+ CD133(+ fraction of expanded cells and that CD34(+ CD133(+ cell number correlates with SCID repopulating activity before and after culture. The expanded cells mediate long-term hematopoiesis and serial reconstitution in NSG mice. Furthermore, they efficiently reconstitute not only neonate but also adult NSG recipients, generating human blood cell populations similar to those reported in mice reconstituted with uncultured human HSCs. These findings suggest an expansion of long term HSCs in our culture and show that expression of CD34 and CD133 serves as a marker for HSC activity in human cord blood cell cultures. The ability to expand human HSCs in vitro should facilitate clinical use of HSCs and large-scale construction of humanized mice from the same donor for research applications.

  20. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Science.gov (United States)

    Nuss, Jonathan E; Kehn-Hall, Kylene; Benedict, Ashwini; Costantino, Julie; Ward, Michael; Peyser, Brian D; Retterer, Cary J; Tressler, Lyal E; Wanner, Laura M; McGovern, Hugh F; Zaidi, Anum; Anthony, Scott M; Kota, Krishna P; Bavari, Sina; Hakami, Ramin M

    2014-01-01

    Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV). Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry) with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90), as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  1. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Directory of Open Access Journals (Sweden)

    Jonathan E Nuss

    Full Text Available Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV. Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90, as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  2. Human factors in cybersecurity; examining the link between Internet addiction, impulsivity, attitudes towards cybersecurity, and risky cybersecurity behaviours.

    Science.gov (United States)

    Hadlington, Lee

    2017-07-01

    The present study explored the relationship between risky cybersecurity behaviours, attitudes towards cybersecurity in a business environment, Internet addiction, and impulsivity. 538 participants in part-time or full-time employment in the UK completed an online questionnaire, with responses from 515 being used in the data analysis. The survey included an attitude towards cybercrime and cybersecurity in business scale, a measure of impulsivity, Internet addiction and a 'risky' cybersecurity behaviours scale. The results demonstrated that Internet addiction was a significant predictor for risky cybersecurity behaviours. A positive attitude towards cybersecurity in business was negatively related to risky cybersecurity behaviours. Finally, the measure of impulsivity revealed that both attentional and motor impulsivity were both significant positive predictors of risky cybersecurity behaviours, with non-planning being a significant negative predictor. The results present a further step in understanding the individual differences that may govern good cybersecurity practices, highlighting the need to focus directly on more effective training and awareness mechanisms.

  3. Examining the cross-cultural sensitivity of the Revised Two-Factor Study Process Questionnaire (R-SPQ-2F and validation of a Dutch version.

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    Ann Stes

    Full Text Available The Revised Two-Factor Study Process Questionnaire (R-SPQ-2F is used to examine students' study approaches in higher education. The questionnaire assumes to measure two factors: a deep and a surface study approach. Analyses into the validity and reliability of the original English R-SPQ-2F yielded positive results. In this study, we examined the degree to which these positive results can also be found for the Dutch version that we developed. By comparing our results with the results of earlier studies in different cultures, we conclude cross-cultural sensitivity is an important point to be borne in mind when using the R-SPQ-2F. Our research supports the validity and reliability of our Dutch version of the R-SPQ-2F.

  4. Modifiable risk factors including sunlight exposure and fish consumption are associated with risk of hypertension in a large representative population from Macau.

    Science.gov (United States)

    Ke, Liang; Ho, Jacky; Feng, Jianzhang; Mpofu, Elias; Dibley, Michael J; Feng, Xiuhua; Van, Florance; Leong, Sokman; Lau, Winne; Lueng, Petra; Kowk, Carrie; Li, Yan; Mason, Rebecca S; Brock, Kaye E

    2014-10-01

    Chinese populations are known to be at risk for vitamin D deficiency, with some evidence that this is due to lack of exposure to sunlight. Vitamin D deficiency and/or low sun exposure have been associated with higher incidence of hypertension in Caucasians. Thus, we investigated these associations in a Chinese population with a high rate of hypertension. From a random household survey of 1410 residents aged ≥18 years, height, weight and blood pressure were measured and demographic, exercise and dietary data were collected, as well as estimated hours of sunlight exposure on weekdays and weekends (in winter and summer). Modifiable predictors of hypertension in these data were lack of sunlight exposure and low intake of fish as well as smoking, obesity and lack of exercise. When investigated in a linear model, sunlight exposure was negatively associated with hypertension (β=-0.072, pexposure per day compared to none was associated with less hypertension (OR=0.6, 95% CI: 0.4-0.8). Similarly, consuming either oily fish or seafood more than four times per week compared to less was also associated with less hypertension (oily fish (OR=0.4, 95% CI: 0.3-0.5); seafood consumption (OR=0.8, 95% CI: 0.7-0.9)). Having daily moderate physical activity compared to none was also associated with a lower risk of hypertension (OR=0.8, 95% CI: 0.7-0.9). In contrast, being obese compared to normal weight and having more than five pack-years of smoking compared to none were associated with a higher risk of hypertension (OR=4.6, 95% CI: 3.7-5.7; OR=1.4, 95% CI: 1.0-1.8, respectively). The major new findings of this study are that more sun exposure and high weekly fish consumption (especially oily fish) may be potentially modifiable independent factors for protecting against risk of hypertension in this population. This article is part of a Special Issue entitled '16th Vitamin D Workshop'. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Reference values of lead in blood and related factors among Korean adolescents: the Korean National Health and Nutrition Examination Survey 2010-2013

    OpenAIRE

    Choi, Min-Gyu; Park, Mi-Jung; Kim, Shin-Hye

    2016-01-01

    Purpose This study aimed to assess the reference values and factors influencing blood lead levels among Korean adolescents. Methods The study population consisted of 1,585 adolescents (801 males, 784 females; aged 10-19 years) who participated in the Korea National Health and Nutrition Examination Survey 2010-2013. We analyzed blood lead concentrations in relation to demographic/lifestyle characteristics for all participants. "Reference values" of blood lead levels were calculated as the uppe...

  6. Human factors in cybersecurity; examining the link between Internet addiction, impulsivity, attitudes towards cybersecurity, and risky cybersecurity behaviours

    Directory of Open Access Journals (Sweden)

    Lee Hadlington

    2017-07-01

    Full Text Available The present study explored the relationship between risky cybersecurity behaviours, attitudes towards cybersecurity in a business environment, Internet addiction, and impulsivity. 538 participants in part-time or full-time employment in the UK completed an online questionnaire, with responses from 515 being used in the data analysis. The survey included an attitude towards cybercrime and cybersecurity in business scale, a measure of impulsivity, Internet addiction and a ‘risky’ cybersecurity behaviours scale. The results demonstrated that Internet addiction was a significant predictor for risky cybersecurity behaviours. A positive attitude towards cybersecurity in business was negatively related to risky cybersecurity behaviours. Finally, the measure of impulsivity revealed that both attentional and motor impulsivity were both significant positive predictors of risky cybersecurity behaviours, with non-planning being a significant negative predictor. The results present a further step in understanding the individual differences that may govern good cybersecurity practices, highlighting the need to focus directly on more effective training and awareness mechanisms.

  7. Vascular endothelial growth factor polymorphisms and a synchronized examination of plasma and tissue expression in epithelial ovarian cancers.

    Science.gov (United States)

    Bhaskari, J; Premalata, C S; Shilpa, V; Rahul, B; Pallavi, V R; Ramesh, G; Krishnamoorthy, Lakshmi

    2016-01-01

    In this study, we have analyzed six genetic polymorphisms of the VEGF-A gene and correlated the genetic data with plasma and tissue expression of VEGF-A in epithelial ovarian carcinomas. A total of 130 cases including 95 malignant carcinomas, 17 low malignant potential and 18 benign tumours were studied. rs699947, rs833061, rs1570360, rs2010963, rs1413711 and rs3025039 were studied by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP). Plasma levels of VEGF-A were estimated by enzyme-linked immunosorbent assay (ELISA) and tissue expression of VEGF-A by immunohistochemistry (IHC). Four polymorphisms of the above excluding rs699947 and rs3025039 showed significant association with malignancy, and we observed the presence of positive correlation between haplotype CCGGCC and increased expression of VEGF-A in both plasma and tissues which also correlated with poor prognosis and recurrence suggesting a probable increase in resistance to treatment in such carriers. Highly upregulated tissue expression of VEGF-A was seen in all epithelial ovarian carcinomas with intensity of expression increasing from benign to malignant cases. ELISA data from our study showed an increase in circulating levels of VEGF-A in malignancies. VEGF-A plasma levels can be employed as a biomarker for high-grade malignancy in epithelial ovarian cancers alongside tissue expression and CA-125 levels. This study is unique due to the fact that a simultaneous analysis of plasma and tissue expression has been demonstrated and is a first such study in epithelial ovarian cancers and representing the Indian population (South-east Asian) synchronized with genetic polymorphism data as well.

  8. If I Can Do for My People, I Can Do for Myself: Examining Racial Factors for Their Influence on Goal Efficacy for Black College Students

    Science.gov (United States)

    Bentley-Edwards, Keisha L.; Agonafer, Edden; Edmonston, Rashida; Flannigan, Alaina

    2016-01-01

    Using a sociocultural stress and coping approach, this study focuses on the antecedents of goal efficacy, or an individual's appraisal that they can achieve their goals. Despite being in college, less than half of the participants demonstrated goal efficacy. Racial factors including racial cohesion, racial dissonance and race-related stress, along…

  9. The prevalence and risk factors for pterygium in South Korea: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010

    Science.gov (United States)

    Mun, Gui Hyeong

    2016-01-01

    OBJECTIVES To determine the prevalence and risk factors for pterygium in the adult Korean population of South Korea. METHODS Data were analyzed from 9,193 participants who were 40 years of age or older from the Korea National Health and Nutrition Examination Survey (KNHANES), conducted from 2009 to 2010. Standardized slit-lamp examinations were performed by study ophthalmologists to examine the anterior segment for evidence of pterygium. Pterygium was graded clinically as T1 (atrophic), T2 (intermediate), or T3 (opaque). Every participant underwent ocular and systemic examinations, as well as interviewer-administered questionnaires. Any evidence of pterygium and observed association between the risk factors were recorded. RESULTS The mean age of the subjects was 55.7 (±0.2) years. Of the 9,193 eligible subjects, 935 had pterygium in at least one eye. In a multivariate logistic regression analysis adjusted for age and sex, pterygium was significantly associated with rural vs. urban residence (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.4 to 2.0), lower level of education (OR, 4.5; 95% CI, 3.1 to 6.6), low income (OR, 1.3; 95% CI, 1.0 to 1.8), smoking (OR, 0.7; 95% CI, 0.5 to 1.0), and more hours of sun exposure (OR, 1.5; 95% CI, 1.2 to 1.8). After adjusting for all variables, the prevalence of pterygium was significantly associated with age, sex, residence, education level, and smoking. CONCLUSIONS This is a nationwide epidemiologic study in South Korea to assess the prevalence of and risk factors for pterygium. The overall prevalence of pterygium was 8.8% among Koreans aged 40 years or older. Older age, male gender, rural residence, lower level of education, and non-smoking were associated with the development of pterygium. PMID:27156345

  10. An exploratory examination of the relationship between motivational factors and the degree to which the higher education faculty integrate computer-mediated communication (CMC) tools into their courses

    Science.gov (United States)

    Murage, Francis Ndwiga

    The stated research problem of this study was to examine the relationship between motivational factors and the degree to which the higher education faculty integrate CMC tools into their courses. The study population and sample involved higher education faculty teaching in science departments at one public university and three public colleges in the state of West Virginia (N = 153). A Likert-type rating scale survey was used to collect data based on the research questions. Two parts of the survey were adopted from previous studies while the other two were self-constructed. Research questions and hypothesis were analyzed using both descriptive and inferential analyses. The study results established a positive relationship between motivational factors and the degree the higher education faculty integrate CMC tools in their courses. The results in addition established that faculty are highly motivated to integrate CMC tools by intrinsic factors, moderately motivated by environmental factors and least motivated by extrinsic factors. The results also established that the most integrated CMC tools were those that support asynchronous methods of communication while the least integrated were those that support synchronous methods of communication. A major conclusion made was that members of higher education faculty are more likely to be motivated to integrate CMC tools into their courses by intrinsic factors rather than extrinsic or environmental factors. It was further concluded that intrinsic factors that supported and enhanced student learning as well as those that were altruistic in nature significantly influenced the degree of CMC integration. The study finally concluded that to larger extent, there is a relationship between motivational factors and the degree to which the higher education faculty integrate CMC tools in their courses. A major implication of this study was that institutions that wish to promote integration of CMC technologies should provide as much

  11. An examination of the mediating role of salt knowledge and beliefs on the relationship between socio-demographic factors and discretionary salt use: a cross-sectional study

    Science.gov (United States)

    2013-01-01

    Background Discretionary salt use varies according to socio-demographic factors. However, it is unknown whether salt knowledge and beliefs mediate this relationship. This study examined the direct and indirect effect of socio-demographic factors on salt knowledge and discretionary salt use in a sample of 530 Australian adults. Methods An internet based cross-sectional survey was used to collect data for this study. Participants completed an online questionnaire which assessed their salt knowledge, beliefs and salt use behaviour. Mplus was used to conduct structural equation modelling to estimate direct and indirect effects. Results The mean age of the participants was 49.2 years, and about a third had tertiary education. Discretionary salt use was inversely related to age (r=-0.11; psocio-demographic groups in their use of discretionary salt use can potentially be reduced through targeted salt knowledge and awareness campaigns. PMID:23418906

  12. Prevalence of and factors associated with lens opacities in a Korean adult population with and without diabetes: the 2008-2009 Korea National Health and Nutrition Examination Survey.

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    Tae Nyun Kim

    Full Text Available OBJECTIVE: We examined the prevalence of and factors associated with lens opacities in a Korean adult population with and without diabetes. RESEARCH DESIGN AND METHODS: Among the 11,163 adults (≥ 19 years old from the fourth Korea National Health and Nutrition Examination Survey in 2008-2009, the data from laboratory tests, nutritional surveys, and slit-lamp examinations of 10,248 persons (4,397 men, 5,851 women were examined. Cataract was defined as the presence of any nuclear, cortical, subcapsular, or mixed cataract in at least one eye, using the Lens Opacities Classification System III. RESULTS: The weighted prevalence of cataracts were 23.5% [95% confidence interval (CI, 21.7-25.4] in a Korean adult population (19-39 years old, 1.8% [1.3-2.5], 40-64 years old, 25.2% [22.5-28.1], ≥ 65 years old, 87.8% [85.4-89.9]and 54.7% [50.1-59.2] in a diabetic population(19-39 years old, 11.6% [4.5-26.5], 40-64 years old, 41.1% [35.4-47.0], ≥ 65 years old, 88.3% [83.5-91.8]. In a logistic regression analysis, age, myopia, and the presence of diabetes were independent risk factors. For young (age 19-39 years and middle aged (age 40-65 years adults with diabetes, the OR of having a lens opacity is 5.04 [1.41-17.98] and 1.47 [1.11-1.94], respectively, as those without diabetes, whereas for adults aged 65 and older, there was no difference in the prevalence of cataract. CONCLUSIONS: According to these national survey data, ∼ 24% of Korean adults and ∼ 55% of people with diabetes have cataracts. The presence of diabetes was independently associated with cataracts in young and middle aged adults.

  13. Factors related to the practice of breast self examination (BSE and Pap smear screening among Malaysian women workers in selected electronics factories

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    Shamsuddin K

    2003-05-01

    Full Text Available Abstract Background The Malaysian Ministry of Health promotes breast self-examination (BSE for all women, and Pap smear screening every three years for all sexually active women ages 20 years and above. The objectives of this paper were to examine the practice of these two screening tests among women production workers in electronics factories, and to identify factors related to practice. Methods This was a cross-sectional survey of women production workers from ten electronics factories. Data was collected by a self-administered questionnaire from a total of 1,720 women. The chi-square test, odds ratio and binomial logistic regression were used in bivariate and multivariate analysis. Results Prevalence rates were 24.4% for BSE once a month, and 18.4% for Pap smear examination within the last three years. Women who were significantly more likely to perform BSE every month were 30 years and older, Malays, with upper secondary education and above, answered the BSE question correctly, and had a Pap smear within the last three years. The proportion of women who had a Pap smear within the last three years were significantly higher among those who were older, married, with young children, on the contraceptive pill or intra-uterine device, had a medical examination within the last five years, answered the Pap smear question correctly, and performed BSE monthly. Conclusion Screening practice rates in this study were low when compared to national rates. Socio-demographic and health care factors significantly associated with screening practice are indicative of barriers which should be further understood so that more effective educational and promotional strategies could be developed.

  14. A prospective examination of the path from child abuse and neglect to illicit drug use in middle adulthood: the potential mediating role of four risk factors.

    Science.gov (United States)

    Wilson, Helen W; Widom, Cathy Spatz

    2009-03-01

    This study examines prostitution, homelessness, delinquency and crime, and school problems as potential mediators of the relationship between childhood abuse and neglect (CAN) and illicit drug use in middle adulthood. Children with documented cases of physical and sexual abuse and neglect (ages 0-11) during 1967-1971 were matched with non-maltreated children and followed into middle adulthood (approximate age 39). Mediators were assessed in young adulthood (approximate age 29) through in-person interviews between 1989 and 1995 and official arrest records through 1994 (N = 1,196). Drug use was assessed via self-reports of past year use of marijuana, psychedelics, cocaine, and/or heroin during 2000-2002 (N = 896). Latent variable structural equation modeling (SEM) was used to test: (1) a four-factor model with separate pathways from CAN to illicit drug use through each of the mediating risk factors and (2) a second-order model with a single mediating risk factor comprised of prostitution, homelessness, delinquency and crime, and poor school performance. Analyses were performed separately for women and men, controlling for race/ethnicity and early drug use. In the four-factor model for both men and women, CAN was significantly related to each of the mediators, but no paths from the mediators to drug use were significant. For women, the second-order risk factor mediated the relationship between CAN and illicit drug use in middle adulthood. For men, neither child abuse and neglect nor the second-order risk factor predicted drug use in middle adulthood. These results suggest that for women, the path from CAN to middle adulthood drug use is part of a general "problem behavior syndrome" evident earlier in life.

  15. Using estimated factor scores from a bifactor analysis to examine the unique effects of the latent variables measured by the WAIS-IV on academic achievement.

    Science.gov (United States)

    Kranzler, John H; Benson, Nicholas; Floyd, Randy G

    2015-12-01

    This study used estimated factor scores from a bifactor analysis of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) to examine the unique effects of its latent variables on academic achievement. In doing so, we addressed the potential limitation of multicollinearity in previous studies of the incremental validity of the WAIS-IV. First, factor scores representing psychometric g and 4 group factors representing the WAIS-IV index scales were computed from a bifactor model. Subtest and composite scores for the Wechsler Individual Achievement Test-Third Edition (WIAT-II) were then predicted from these estimated factor scores in simultaneous multiple regression. Results of this study only partially replicated the findings of previous research on the incremental validity of scores that can be derived from performance on the WAIS-IV. Although we found that psychometric g is the most important underlying construct measured by the WAIS-IV for the prediction of academic achievement in general, results indicated that the unique effect of Verbal Comprehension is also important for predicting achievement in reading, spelling, and oral communication skills. Based on these results, measures of both psychometric g and Verbal Comprehension could be cautiously interpreted when considering high school students' performance in these areas of achievement.

  16. Gender-Specific Associations between Socioeconomic Status and Psychological Factors and Metabolic Syndrome in the Korean Population: Findings from the 2013 Korean National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Cho, Kyoung Im; Kim, Bo Hyun; Je, Hyung Gon; Jang, Jae Sik; Park, Yong Hyun

    2016-01-01

    We aimed to assess the gender-specific associations between psychological factors and socioeconomic status (SES) and metabolic syndrome (MetS) in Korean adults. We examined 4,689 Korean adults aged 20-79 years who participated in the 2013 Korean National Health Examination and Nutrition Survey. With regard to SES, occupation status (none, manual, and nonmanual), marital status (single, married, divorced, and widowed), and psychological factors (detection of stress, depressive symptoms, and suicidal thoughts) were determined via questionnaires. Compared with married men, single and divorced men exhibited ORs (95% confidence interval [CIs]) for MetS of 0.45 (0.31-0.65) and 1.61 (1.02-2.55), respectively, after adjusting for covariates. However, this association was not significant in women. Compared with those in the lowest household income group and least educated group in women, the ORs for MetS in the highest income group and the most educated group were 0.63 (CI 0.46-0.86) and 0.46 (CI 0.32-0.67), respectively. Suicidal thoughts in men (OR 1.64, CI 1.03-2.61) and perceived stress in women (OR 1.26, CI 1.01-1.59) were associated with MetS. In this study, MetS has gender-specific associations with lower SES and psychological factors. Thus, gender-specific public health interventions based on SES and psychological factors are needed to prevent and treat MetS and reduce additional cardiovascular disease risk.

  17. Gender-Specific Associations between Socioeconomic Status and Psychological Factors and Metabolic Syndrome in the Korean Population: Findings from the 2013 Korean National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Kyoung Im Cho

    2016-01-01

    Full Text Available We aimed to assess the gender-specific associations between psychological factors and socioeconomic status (SES and metabolic syndrome (MetS in Korean adults. We examined 4,689 Korean adults aged 20–79 years who participated in the 2013 Korean National Health Examination and Nutrition Survey. With regard to SES, occupation status (none, manual, and nonmanual, marital status (single, married, divorced, and widowed, and psychological factors (detection of stress, depressive symptoms, and suicidal thoughts were determined via questionnaires. Compared with married men, single and divorced men exhibited ORs (95% confidence interval [CIs] for MetS of 0.45 (0.31–0.65 and 1.61 (1.02–2.55, respectively, after adjusting for covariates. However, this association was not significant in women. Compared with those in the lowest household income group and least educated group in women, the ORs for MetS in the highest income group and the most educated group were 0.63 (CI 0.46–0.86 and 0.46 (CI 0.32–0.67, respectively. Suicidal thoughts in men (OR 1.64, CI 1.03–2.61 and perceived stress in women (OR 1.26, CI 1.01–1.59 were associated with MetS. In this study, MetS has gender-specific associations with lower SES and psychological factors. Thus, gender-specific public health interventions based on SES and psychological factors are needed to prevent and treat MetS and reduce additional cardiovascular disease risk.

  18. Evaluation of socioeconomic status as a risk factor of pterygium using the Korean National Health and Nutrition Examination Survey 2010 to 2011

    Science.gov (United States)

    Lee, Young Bok; Kim, Su Young; Park, Yong Gyu; Han, Kyung Do; Kim, Jin-Wou; Chae, Hiun Suk; Lee, Young Chun

    2017-01-01

    Abstract Pterygium is a common conjunctival disorder. The socioeconomic risk factors of pterygium have not been systematically evaluated in Korea. The study investigated risk factors of pterygium considering socioeconomic status. Participants were 9839 adults aged 19 to 74 years, who underwent ophthalmic slit-lamp examinations as part of the Korean National Health and Nutrition Examination Survey 2010 to 2011. Pterygium was diagnosed as a growth of fibrovascular tissue over the cornea. The socioeconomic risk factors were analyzed in association with the presence of pterygium. Multiple logistic regression analysis was used to evaluate the odds ratios for differences in socioeconomic status. The presence of pterygium was associated with diabetes mellitus, hypertension, metabolic syndrome, and sun exposure time (>5 h/d). The blood level of 25-hydroxyvitamin D was higher in the pterygium group than in the control group, but both groups were deficient in 25-hydroxyvitamin D compared with the normal reference level. Pterygium was almost 3 times as frequent among persons who worked outdoors, such as skilled agricultural, forestry, and fishery workers, than among those who worked indoors (odds ratio 3.061, 95% confidence interval 1.946–4.813). Low educational status and longer working hours were also significantly associated with pterygium. This study used a nationwide population-based survey conducted by the Korean Centers for Disease Control and Prevention to reveal that pterygium is associated with low socioeconomic status. Efforts should be made to reduce the risk of pterygium by changing modifiable risk factors, especially among people with low socioeconomic status. PMID:28296766

  19. A cross-sectional study examining Campylobacter and other zoonotic enteric pathogens in dogs that frequent dog parks in three cities in south-western Ontario and risk factors for shedding of Campylobacter spp.

    Science.gov (United States)

    Procter, T D; Pearl, D L; Finley, R L; Leonard, E K; Janecko, N; Reid-Smith, R J; Weese, J S; Peregrine, A S; Sargeant, J M

    2014-05-01

    An estimated 6 million pet dogs live in Canadian households with the potential to transmit zoonotic pathogens to humans. Dogs have been identified as carriers of Salmonella, Giardia and Campylobacter spp., particularly Campylobacter upsaliensis, but little is known about the prevalence and risk factors for these pathogens in pet dogs that visit dog parks. This study examined the prevalence of these organisms in the faeces of dogs visiting dog parks in three cities in south-western Ontario, as well as risk factors for shedding Campylobacter spp. and C. upsaliensis. From May to August 2009, canine faecal samples were collected at ten dog parks in the cities of Guelph and Kitchener-Waterloo, Ontario, Canada. Owners were asked to complete a questionnaire related to pet characteristics and management factors including age, diet and activities in which the dog participates. Faecal samples were collected from 251 dogs, and 189 questionnaires were completed. Salmonella, Giardia and Campylobacter spp. were present in 1.2%, 6.4% and 43.0% of faecal samples, respectively. Of the Campylobacter spp. detected, 86.1% were C. upsaliensis, 13% were C. jejuni and 0.9% were C. coli. Statistically significant sparing factors associated with the shedding of Campylobacter spp. included the feeding of a commercial dry diet and the dog's exposure to compost. Age of dog had a quadratic effect, with young dogs and senior dogs having an increased probability of shedding Campylobacter spp. compared with adult dogs. The only statistically significant risk factor for shedding C. upsaliensis was outdoor water access including lakes and ditches, while dogs >1 year old were at a lower risk than young dogs. Understanding the pet-related risk factors for Campylobacter spp. and C. upsaliensis shedding in dogs may help in the development of awareness and management strategies to potentially reduce the risk of transmitting this pathogen from dogs to humans.

  20. Factors Associated with Diabetic Retinopathy and Nephropathy Screening in Korea: The Third and Fourth Korea National Health and Nutrition Examination Survey (KNHANES III and IV)

    OpenAIRE

    Rim, Tyler Hyung Taek; Byun, Il Hwan; Kim, Han Sang; Lee, Sang Yeul; Yoon, Jin Sook

    2013-01-01

    This cross-sectional study was done to identify and determine the socio-demographic and health-related factors associated with diabetic retinopathy and nephropathy screening in Korea. Participants included 2,660 adults, aged 40 or older, with diabetes. Of the 2,660 adults, 998 (37%) and 1,226 (46.1%) had received a diabetic retinopathy and a nephropathy screening within one year, respectively. Regarding retinopathy, subjects older than 65, living in urban areas, with high educational levels, ...

  1. Collaborative Group on Hormonal Factors in Breast cancer: Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83000 women with breast cancer from 16 countries

    NARCIS (Netherlands)

    Beral, V.; Bull, D.; Doll, R.; Peto, R.; Reeves, G.; van den Brandt, P.A.; Goldbohm, R.A.

    2004-01-01

    Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries. Beral V, Bull D, Doll R, Peto R, Reeves G; Collaborative Group on Hormonal Factors in Breast Cancer. BACKGROUND: The Collaborative Group on Hormo

  2. Collaborative Group on Hormonal Factors in Breast cancer: Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83000 women with breast cancer from 16 countries

    NARCIS (Netherlands)

    Beral, V.; Bull, D.; Doll, R.; Peto, R.; Reeves, G.; van den Brandt, P.A.; Goldbohm, R.A.

    2004-01-01

    Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries. Beral V, Bull D, Doll R, Peto R, Reeves G; Collaborative Group on Hormonal Factors in Breast Cancer. BACKGROUND: The Collaborative Group on

  3. Correlations between Poor Micronutrition in Family Members and Potential Risk Factors for Poor Diet in Children and Adolescents Using Korean National Health and Nutrition Examination Survey Data

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    Hye Ah Lee

    2015-08-01

    Full Text Available Based on data from the 2010–2011 Korean National Health and Nutrition Examination Survey, we investigated correlations between micronutrients in the diet of family members and the possible risk factors for children and adolescents consuming an inadequate diet. We examined two-generation households with children aged 2–18 years. The quality of the family diet with regard to the following nine nutrients (protein, calcium, phosphorous, iron, vitamin A, vitamin B1, vitamin B2, niacin, and vitamin C was assessed based on the Index of Nutritional Quality. Correlations between quality of diet and selected variables were analyzed using the Statistical Analysis for Genetic Epidemiology software, and those between diet quality and potential risk factors for poor diet in offspring were analyzed using multinomial logistic regression. Overall, calcium was the most commonly under-consumed micronutrient. More than half of sons and daughters showed insufficient vitamin A, vitamin C, and iron intake, and both mothers and fathers showed insufficiency with respect to vitamin A, vitamin B2, and vitamin C. The correlation between a poor diet in parents and that in offspring was 0.17 (p < 0.0001, and this correlation coefficient was higher between mothers and offspring than between fathers and offspring. Additionally, eating breakfast provided a significant protective effect against the risk of poor nutrition in offspring, even after adjusting for covariates. Our results add to evidence indicating that children should be encouraged to eat breakfast to improve the quality of their diet.

  4. Effects of diet composition on weight loss, metabolic factors and biomarkers in a 1-year weight loss intervention in obese women examined by baseline insulin resistance status.

    Science.gov (United States)

    Rock, Cheryl L; Flatt, Shirley W; Pakiz, Bilge; Quintana, Elizabeth L; Heath, Dennis D; Rana, Brinda K; Natarajan, Loki

    2016-11-01

    Obesity is a risk factor for postmenopausal breast cancer incidence and premenopausal and postmenopausal breast cancer mortality, which may be explained by several metabolic and hormonal factors (sex hormones, insulin resistance, and inflammation) that are biologically related. Differential effects of dietary composition on weight loss and these metabolic factors may occur in insulin-sensitive vs. insulin-resistant obese women. To examine the effect of diet composition on weight loss and metabolic, hormonal and inflammatory factors in overweight/obese women stratified by insulin resistance status in a 1-year weight loss intervention. Nondiabetic women who were overweight/obese (n=245) were randomly assigned to a lower fat (20% energy), higher carbohydrate (65% energy) diet; a lower carbohydrate (45% energy), higher fat (35% energy) diet; or a walnut-rich (18% energy), higher fat (35% energy), lower carbohydrate (45% energy) diet. All groups lost weight at follow-up (Pdiet×time×insulin resistance status interaction was not statistically significant in the model for overall weight loss, although insulin sensitive women at 12months lost more weight in the lower fat vs. lower carbohydrate group (7.5kg vs. 4.3kg, P=0.06), and in the walnut-rich vs. lower carbohydrate group (8.1kg vs. 4.3kg, P=0.04). Sex hormone binding globulin increased within each group except in the lower carbohydrate group at 12months (Pdiet composition on weight loss depending on insulin resistance status. Prescribing walnuts is associated with weight loss comparable to a standard lower fat diet in a behavioral weight loss intervention. Weight loss itself may be the most critical factor for reducing the chronic inflammation associated with increased breast cancer risk and progression. Copyright © 2016. Published by Elsevier Inc.

  5. Risk factors for gastroesophageal reflux disease, reflux esophagitis and non-erosive reflux disease among Chinese patients undergoing upper gastrointestinal endoscopic examination

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    AIM: To analyze the spectrum and risk factors of gastroesophageal reflux disease (GERD) based on presenting symptoms and endoscopic findings. METHODS: A cross-sectional survey in a cluster random sample was conducted from November 2004 to June 2005 using a validated Chinese version Reflux Disease Questionnaire (RDQ) and other items recording the demographic characteristics and potential risk factors for GERD. Subjects were defined as having GERD symptoms according to the RDQ score (>12). All subjects were endoscopied and the definition and severity of erosive esephagitis were evaluated by Los Angeles classification.The statistical analysis was performed with SPSS13.0 programs. RESULTS: Of 2231 recruited participants, 701 (31.40%) patients were diagnosed as having GFRD while 464 (20.80%) patients had objective findings of reflux esophagitis (RE). Of those 464 patients, only 291 (13.00%) were reported as subjects with GERD symptoms. A total of 528 (23.70%) patients were found to have GERD symptoms, including 19.50% patients with grade A or B reflux esophagitis, 0.90% with grade C and 0.40% with grade D. On multivariate analysis, old age,male, moderate working burden, divorced/widowed and strong tea drinking remained as significant independent risk factors for erosive esophagitis. Meanwhile, routine usage of greasy food and constipation were considered as significant independent risk factors for non-erosive reflux disease (NERD).CONCLUSION: GERD is one of the common GI diseases with a high occurrence rate in China and its main associated factors include sex, anthropometrical variables and sociopsychological characteristics.

  6. Examining the Factors Related to Mortality Aamongst One Year Old and Younger Children in Yazd City During 2011 to 2013 Period

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    Abbas Askari Nodoushan

    2015-06-01

    Materials and Methods: This descriptive-analytical study was conducted using control-test group method. All recorded cases of mortality for children in Yazd city during the first year of their life were included in statistical population, while for each case of mortality two cases of living children were examined as control group. The data were collected by direct visits on healthcare centers in the city and examining case files for children. Obtained data were analyzed using SPSS 20 software package. Results: 116 mortality cases were examined in total which included 41.4% boys and 58.6% girls. Some variables such as type of marriage between parents, mother and father’s education level, type of labor and number of previous pregnancies were significantly related to children’s mortality rate. Conclusion: suggest that paying specific attention to infants at the time of birth, improving knowledge level amongst mothers and families, providing standard level healthcare prior to pregnancy and after that, and also developing programs which aim for improving economic-social and cultural status amongst women and men would be effective on reducing children mortality rates.

  7. Association between history and physical examination factors and change in lumbar multifidus muscle thickness after spinal manipulation in patients with low back pain.

    Science.gov (United States)

    Koppenhaver, Shane L; Fritz, Julie M; Hebert, Jeffrey J; Kawchuk, Greg N; Parent, Eric C; Gill, Norman W; Childs, John D; Teyhen, Deydre S

    2012-10-01

    Understanding the clinical characteristics of patients with low back pain (LBP) who display improved lumbar multifidus (LM) muscle function after spinal manipulative therapy (SMT) may provide insight into a potentially synergistic interaction between SMT and exercise. Therefore, the purpose of this study was to identify the baseline historical and physical examination factors associated with increased contracted LM muscle thickness one week after SMT. Eighty-one participants with LBP underwent a baseline physical examination and ultrasound imaging assessment of the LM muscle during submaximal contraction before and one week after SMT. The relationship between baseline examination variables and 1-week change in contracted LM thickness was assessed using correlation analysis and hierarchical multiple linear regression. Four variables best predicted the magnitude of increases in contracted LM muscle thickness after SMT. When combined, these variables suggest that patients with LBP, (1) that are fairly acute, (2) have at least a moderately good prognosis without focal and irritable symptoms, and (3) exhibit signs of spinal instability, may be the best candidates for a combined SMT and lumbar stabilization exercise (LSE) treatment approach.

  8. Impact of dining out on nutritional intake and metabolic syndrome risk factors: data from the 2011 Korean National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Oh, Chorong; Kim, Hak-Seon; No, Jae-Kyung

    2015-02-14

    The frequency of dining out has rapidly increased; however, the independent associations between dining out, metabolic syndrome risk factors and nutritional status have not been well characterised. The aim of the present study was to investigate the associations between dining out, nutritional intakes and metabolic syndrome risk factors among Korean adults, using data from the 2011 Korean National Health and Nutrition Examination Survey. Frequency of dining out was significantly associated with intake of nutrients such as energy, water, protein, fat, carbohydrate, Ca, Na, vitamin A and carotene. Especially, the result revealed that Korean adults had insufficient Ca intake compared with the Korean reference intake (700 mg). As the frequency of dining out increased, so did energy intake. In addition, individuals who dined out seven or more times per week experienced a 64% higher likelihood of blood pressure abnormalities, an 88% higher likelihood of waist circumference abnormalities, and a 32% higher likelihood of low HDL-cholesterol levels than those who dined out less than once per week. BMI was not associated with the frequency of dining out. Our findings suggest that strategies to modify dining-out behaviour could reduce metabolic syndrome risk factors via improved nutrition.

  9. Biomechanical factors and physical examination findings in osteoarthritis of the knee: associations with tissue abnormalities assessed by conventional radiography and high-resolution 3.0 Tesla magnetic resonance imaging

    Science.gov (United States)

    2012-01-01

    Introduction We aimed to explore the associations between knee osteoarthritis (OA)-related tissue abnormalities assessed by conventional radiography (CR) and by high-resolution 3.0 Tesla magnetic resonance imaging (MRI), as well as biomechanical factors and findings from physical examination in patients with knee OA. Methods This was an explorative cross-sectional study of 105 patients with knee OA. Index knees were imaged using CR and MRI. Multiple features from CR and MRI (cartilage, osteophytes, bone marrow lesions, effusion and synovitis) were related to biomechanical factors (quadriceps and hamstrings muscle strength, proprioceptive accuracy and varus-valgus laxity) and physical examination findings (bony tenderness, crepitus, bony enlargement and palpable warmth), using multivariable regression analyses. Results Quadriceps weakness was associated with cartilage integrity, effusion, synovitis (all detected by MRI) and CR-detected joint space narrowing. Knee joint laxity was associated with MRI-detected cartilage integrity, CR-detected joint space narrowing and osteophyte formation. Multiple tissue abnormalities including cartilage integrity, osteophytes and effusion, but only those detected by MRI, were found to be associated with physical examination findings such as crepitus. Conclusion We observed clinically relevant findings, including a significant association between quadriceps weakness and both effusion and synovitis, detected by MRI. Inflammation was detected in over one-third of the participants, emphasizing the inflammatory component of OA and a possible important role for anti-inflammatory therapies in knee OA. In general, OA-related tissue abnormalities of the knee, even those detected by MRI, were found to be discordant with biomechanical and physical examination features. PMID:23039323

  10. Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome.

    Science.gov (United States)

    Motlagh, Maria G; Katsovich, Liliya; Thompson, Nancy; Lin, Haiqun; Kim, Young-Shin; Scahill, Lawrence; Lombroso, Paul J; King, Robert A; Peterson, Bradley S; Leckman, James F

    2010-10-01

    Attention-deficit/hyperactivity disorder (ADHD) is frequently diagnosed in children with Tourette syndrome (TS). The basis for this co-occurrence is uncertain. This study aimed to determine if specific pre- and perinatal risk factors, including heavy maternal smoking and severe psychosocial stress during pregnancy, were associated with one or both disorders, or neither. We compared maternal report data on pre- and perinatal risk factors on 222 children between the ages of 7 and 18 years including 45 individuals with TS alone, 52 individuals with ADHD alone, 60 individuals with condition of comorbid TS + ADHD, and 65 unaffected control children. Pre- and perinatal histories as well as psychiatric assessments were performed using standardized questionnaires and semi-structured interviews with the mothers and children. Logistic regression was used to determine the odds ratio for each variable of interest. Compared to the mothers of unaffected control children, the mothers of children with ADHD alone reported higher rates of heavy smoking (>10 cigarettes per day) during pregnancy and higher levels of severe psychosocial stress during pregnancy (OR = 13.5, p high levels of psychosocial stress compared to the control children, but these differences failed to reach statistical significance (heavy smoking: OR = 8.5, p pregnancy were independently associated with a diagnosis of ADHD. TS patients also had higher rates of these risk factors, but the ORs failed to reach statistical significance. Efforts are needed to reduce the frequency of these risk factors in high-risk populations. Future studies, using genetically sensitive designs, are also needed to sort out the causal pathways.

  11. Prevalence of and Factors Associated with Lens Opacities in a Korean Adult Population with and without Diabetes: The 2008–2009 Korea National Health and Nutrition Examination Survey

    Science.gov (United States)

    Kim, Tae Nyun; Lee, Joo Eun; Lee, Eun Ju; Won, Jong Chul; Noh, Jung Hyun; Ko, Kyung Soo; Rhee, Byoung Doo; Kim, Dong-Jun

    2014-01-01

    Objective We examined the prevalence of and factors associated with lens opacities in a Korean adult population with and without diabetes. Research Design and Methods Among the 11,163 adults (≥19 years old) from the fourth Korea National Health and Nutrition Examination Survey in 2008–2009, the data from laboratory tests, nutritional surveys, and slit-lamp examinations of 10,248 persons (4,397 men, 5,851 women) were examined. Cataract was defined as the presence of any nuclear, cortical, subcapsular, or mixed cataract in at least one eye, using the Lens Opacities Classification System III. Results The weighted prevalence of cataracts were 23.5% [95% confidence interval (CI), 21.7–25.4] in a Korean adult population (19–39 years old, 1.8% [1.3–2.5], 40–64 years old, 25.2% [22.5–28.1],≥65 years old, 87.8% [85.4–89.9])and 54.7% [50.1–59.2] in a diabetic population(19–39 years old, 11.6% [4.5–26.5], 40–64 years old, 41.1% [35.4–47.0], ≥65 years old, 88.3% [83.5–91.8]). In a logistic regression analysis, age, myopia, and the presence of diabetes were independent risk factors. For young (age 19–39 years) and middle aged (age 40–65 years) adults with diabetes, the OR of having a lens opacity is 5.04 [1.41–17.98] and 1.47 [1.11–1.94], respectively, as those without diabetes, whereas for adults aged 65 and older, there was no difference in the prevalence of cataract. Conclusions According to these national survey data, ∼ 24% of Korean adults and ∼ 55% of people with diabetes have cataracts. The presence of diabetes was independently associated with cataracts in young and middle aged adults. PMID:24718421

  12. Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6.

    Science.gov (United States)

    Liu, Wan-Ju; Reece-Hoyes, John S; Walhout, Albertha J M; Eisenmann, David M

    2014-05-13

    Hox genes encode master regulators of regional fate specification during early metazoan development. Much is known about the initiation and regulation of Hox gene expression in Drosophila and vertebrates, but less is known in the non-arthropod invertebrate model system, C. elegans. The C. elegans Hox gene lin-39 is required for correct fate specification in the midbody region, including the Vulval Precursor Cells (VPCs). To better understand lin-39 regulation and function, we aimed to identify transcription factors necessary for lin-39 expression in the VPCs, and in particular sought factors that initiate lin-39 expression in the embryo. We used the yeast one-hybrid (Y1H) method to screen for factors that bound to 13 fragments from the lin-39 region: twelve fragments contained sequences conserved between C. elegans and two other nematode species, while one fragment was known to drive reporter gene expression in the early embryo in cells that generate the VPCs. Sixteen transcription factors that bind to eight lin-39 genomic fragments were identified in yeast, and we characterized several factors by verifying their physical interactions in vitro, and showing that reduction of their function leads to alterations in lin-39 levels and lin-39::GFP reporter expression in vivo. Three factors, the orphan nuclear hormone receptor NHR-43, the hypodermal fate regulator LIN-26, and the GATA factor ELT-6 positively regulate lin-39 expression in the embryonic precursors to the VPCs. In particular, ELT-6 interacts with an enhancer that drives GFP expression in the early embryo, and the ELT-6 site we identified is necessary for proper embryonic expression. These three factors, along with the factors ZTF-17, BED-3 and TBX-9, also positively regulate lin-39 expression in the larval VPCs. These results significantly expand the number of factors known to directly bind and regulate lin-39 expression, identify the first factors required for lin-39 expression in the embryo, and hint at a

  13. Examination of the combined effects of chondroitinase ABC, growth factors and locomotor training following compressive spinal cord injury on neuroanatomical plasticity and kinematics.

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    Olivier Alluin

    Full Text Available While several cellular and pharmacological treatments have been evaluated following spinal cord injury (SCI in animal models, it is increasingly recognized that approaches to address the glial scar, including the use of chondroitinase ABC (ChABC, can facilitate neuroanatomical plasticity. Moreover, increasing evidence suggests that combinatorial strategies are key to unlocking the plasticity that is enabled by ChABC. Given this, we evaluated the anatomical and functional consequences of ChABC in a combinatorial approach that also included growth factor (EGF, FGF2 and PDGF-AA treatments and daily treadmill training on the recovery of hindlimb locomotion in rats with mid thoracic clip compression SCI. Using quantitative neuroanatomical and kinematic assessments, we demonstrate that the combined therapy significantly enhanced the neuroanatomical plasticity of major descending spinal tracts such as corticospinal and serotonergic-spinal pathways. Additionally, the pharmacological treatment attenuated chronic astrogliosis and inflammation at and adjacent to the lesion with the modest synergistic effects of treadmill training. We also observed a trend for earlier recovery of locomotion accompanied by an improvement of the overall angular excursions in rats treated with ChABC and growth factors in the first 4 weeks after SCI. At the end of the 7-week recovery period, rats from all groups exhibited an impressive spontaneous recovery of the kinematic parameters during locomotion on treadmill. However, although the combinatorial treatment led to clear chronic neuroanatomical plasticity, these structural changes did not translate to an additional long-term improvement of locomotor parameters studied including hindlimb-forelimb coupling. These findings demonstrate the beneficial effects of combined ChABC, growth factors and locomotor training on the plasticity of the injured spinal cord and the potential to induce earlier neurobehavioral recovery. However

  14. Condicionantes institucionales que influyen en la utilización del examen clínico de mama Institutional factors contributing to the utilization of breast clinical examination

    Directory of Open Access Journals (Sweden)

    Ofelia Poblano-Verástegui

    2004-08-01

    Full Text Available OBJETIVO: Identificar los condicionantes de la utilización del examen clínico de mama, la relación entre ellos y el ejercicio médico institucional. MATERIAL Y MÉTODOS: Entre 1996 y 1997 se hizo un estudio cualitativo en unidades médicas del Instituto Mexicano del Seguro Social y de la Secretaría de Salud. Se realizaron ocho grupos focales: cuatro con mujeres usuarias y cuatro con profesionales de la salud. Participaron 47 usuarias y 29 médicos y enfermeras. La información se interpretó con base en la capacidad de respuesta organizacional a las expectativas de la usuaria, el poder/saber en la organización y el ejercicio médico institucional, a la luz de la Teoría Fundamentada. RESULTADOS: La demanda estuvo condicionada por la percepción de mala calidad de la atención, falta de confianza en el médico y aspectos organizacionales. En la oferta, los médicos varones mostraron desinterés y temor a realizar el examen. Las médicas parecieron interesadas y las usuarias las aceptaron. CONCLUSIONES: Existen barreras psicológicas, culturales, sociales e institucionales en el acceso y utilización del examen clínico de mama. La identificación de estas barreras y su origen pueden apoyar el desarrollo de acciones para mejorar la relación médico-paciente.OBJECTIVE:To identify factors associated with utilization of breast clinical examination (BCE and their relationship with institutional medical practice. MATERIAL AND METHODS: This is a qualitative study conducted between 1996 and 1997 in medical units of Instituto Mexicano del Seguro Social (Mexican Institute of Social Security and Secretaría de Salud (Ministry of Health. Eight focus groups were included: four groups of female users and four groups of health professionals; in total, 47 users and 29 physicians and nurses participated. Interpretations of information were based on the organizational ability to respond to the user's expectations, "ability/knowledge" within the organization

  15. Prevalence of and Factors Associated with Sarcopenia in Korean Cancer Survivors: Based on Data Obtained by the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2011.

    Science.gov (United States)

    Kim, Eun Young; Kim, Kirang; Kim, Young Saing; Ahn, Hee Kyung; Jeong, Yu Mi; Kim, Jeong Ho; Choi, Won-Jun

    2017-01-20

    Using a representative dataset from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011, we analyzed anthropometric and dual-energy X-ray absorptiometry (DXA)-determined body composition findings for 493 cancer survivors (mean age a61.1 ± 12.6 years; 35.7% male). A much higher proportion of men (30.1%) than women (0.6%) met the criteria of sarcopenia. Subjects with a history of lung cancer, genitourinary cancer, or gastric cancer were prone to develop sarcopenia (31.6%, 26.3%, and 21.4%, respectively). Furthermore, sarcopenia was more prevalent among elderly (≥65 years; P protein intake (OR 3.07, 95% CI, 1.30-7.22); these factors are significant predictors of sarcopenia in Korean cancer survivors.

  16. Understanding organizational commitment: A meta-analytic examination of the roles of the five-factor model of personality and culture.

    Science.gov (United States)

    Choi, Daejeong; Oh, In-Sue; Colbert, Amy E

    2015-09-01

    We examined the relationships between the Five-Factor Model (FFM) of personality traits and three forms of organizational commitment (affective, normative, and continuance commitment) and their variability across individualistic and collectivistic cultures. Meta-analytic results based on 55 independent samples from 50 studies (N = 18,262) revealed that (a) all FFM traits had positive relationships with affective commitment; (b) all FFM traits had positive relationships with normative commitment; and (c) Emotional Stability, Extraversion, and Openness to Experience had negative relationships with continuance commitment. In particular, Agreeableness was found to be the trait most strongly related to both affective and normative commitment. The results also showed that Agreeableness had stronger relationships with affective and normative commitment in collectivistic cultures than in individualistic cultures. We provide theoretical and practical implications of these findings for personality, job attitudes, and employee selection and retention.

  17. Prevalence and risk factors of visual impairment and blindness in Korea: the Fourth Korea National Health and Nutrition Examination Survey in 2008-2010.

    Science.gov (United States)

    Rim, Tyler H T; Nam, Jae S; Choi, Moonjung; Lee, Sung C; Lee, Christopher S

    2014-06-01

    To describe the age, gender specific prevalence and risk factors of visual impairment and blindness in Korea. From 2008 to 2010, a total 14 924 randomly selected national representative participants of the Korea National Health and Nutrition Examination Survey underwent additional ophthalmologic examinations by the Korean Ophthalmologic Society. Best Corrected Distance Visual Acuity was measured using an international standard vision chart based on Snellen scale (Jin's vision chart). Independent risk factors for visual impairment were investigated using multivariate logistic regression analysis. The overall prevalence of visual impairment (≤20/40) of adults 40 years and older was 4.1% (95% CI, 3.6-4.6) based on the better seeing eye. The overall prevalence of blindness (≤20/200) for adults 40 years and older was 0.2% (95% CI, 0.1-0.3). Risk indicators of visual impairment were increasing age, low education status, living in rural area, being unemployed, being without spouse and the absence of private health insurance. The visually impaired were more likely to have eye diseases compared with the normal subjects, and they were less likely to utilize eye care. The prevalence of visual impairment was demonstrated to be higher while that of blindness was similar to previous population studies in Asia or U.S. Sociodemographic disparities are present in the prevalence of visual impairment and more targeted efforts are needed to promote vision screening in high risk groups. © 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  18. A Macrolevel Examination of County-Level Risk Factors for Underage Drinking Prevention: Intervention Opportunities to Protect Youth in the State of Georgia

    Directory of Open Access Journals (Sweden)

    Karen E. O'Quin

    2011-01-01

    Full Text Available Introduction. Underage drinking can have profoundly negative impacts on childhood development. This study compares 4 categories of known underage drinking risk factors with alcohol consumption. The social indicators in these categories will be compared in the 10 most-at-risk (MAR counties and the 10 least-at-risk (LAR counties identified in Georgia. Methods. Independent 2-tailed t-tests were conducted to compare group means among MAR and LAR counties for all identified risk factors. Results. Significant differences were observed in all factors included in the poverty and alcohol outlet density categories. Discussion. The findings underscore the importance of better understanding youth drinking, poverty, and alcohol outlet density. However, our findings, supported by previous individual and aggregated level research, support strategies for researchers and policy makers to more proactively respond to poverty-stricken and high-density alcohol outlet indicators. The current ecological evaluation of underage drinking risk assessed on a macrolevel offers insights into the demographic features, social structures, and cultural patterns of counties that potentially predispose youth to greater health risks specifically associated with underage drinking.

  19. Managing Metabolic Syndrome and CHD Risk Factors: Evidence based re-examination of macro nutrients from the Malaysian Population Prospective Study

    Directory of Open Access Journals (Sweden)

    Kalyana Sundram

    2014-11-01

    Full Text Available Our understanding of dietary factors and habits associated with coronary heart disease (CHD risk are undergoing dramatic rethinking in light of fast emerging new scientific data. Multiple risk assessments, especially in understanding Metabolic Syndrome triggers in the population have further confounded understanding and management of traditional risk factors. By far the largest change-impact is being made with regard to fat consumption, especially saturated fats. Emerging evidence, largely through meta-analysis and population studies have regularly challenged the association of saturated fats with increased CHD risk. Indeed there is a growing appreciation that saturates no longer glove-fit risk assessment especially when newer biochemical factors such as lipoprotein particle sizes have emerged to partially explain observed anomalies. The fats we eat may not necessarily be associated with making us fat (obese and obesity is a major health challenge globally. This has redirected dietary assessments more towards excess carbohydrate consumption and their possible adverse outcomes.Drawing on an ongoing population prospective study in Malaysia, such observations are similarly amplified in an urban Malaysian population. Significant carbohydrate associated negative impacts on CHD risk is seen emerging, especially when evaluated against more advanced biochemical markers. Differences in the ethnic groups of the population, modulated through cultural dietary preferences are similarly apparent. In this model, a surprisingly lower risk contributor is the prevailing fat consumption trends in the country. These observations are explained in this presentation aimed at creating better awareness of food factors impacting disease outcomes in an urban Malaysian environment whose make-up includes a substantive South Indian population as well.

  20. 婚前医学检查行为的影响因素研究%Influencing factors on the voluntary premarital medical examination among Chinese population

    Institute of Scientific and Technical Information of China (English)

    李鲁; 顾亚明; 周驰; 周旭东; 郑卫军; 杨廷忠

    2011-01-01

    Objective To explore the factors influencing the premarital medical examination in Chinese population and to discuss the related possible intervention strategies.Methods Data were collected through self-designed questionnaires on 2572 newly married respondents,selected under a stratified randomized sampling method,at Marriage Registration Office in 12 counties in Zhejiang province.Predictive factors were derived from the integrating complementary constructs of Health Belief Model,Theory of Reasoned Action as well as individual demographic characteristics.Multiple logistic multilevel analyses was used as the main statistical method,with individuals as the ' low' and counties as the 'high' levels.Results Behaviors on premarital medical examination showed a clustering trait at the county level (P=0.018) and variance partition coefficients (VPC) of each variables was between 15.40% and 17.58%.There were no statistical significances found in the rates of premarital medical examination among gender,age,residence of Household Registration,education,income,health insurance and history of premarital medical examination.However,significant correlation was seen on occupation of the respondents.The rate of premarital medical examination among the respondents who had not attended medical examination during the last six moths was 1.31times (95% confidence intervals,1.05 -1.65 ) more than those who had,with OR (odds ratio) as 1.51 (95%CI:1.14-2.00) for the pregnant respondents in their first marriage and 0.35 (95%CI:0.23-0.51 )for remarried respondents,compared with women at first marriage but remained unpregnant.Regarding premarital medical examination,the respondents reported greater benefits,less barriers,greater positive behavioral attitudes and normative beliefs to it,with an ORs as 2.32 (95% CI:1.18-4.60),0.71 (95%CI:0.57-0.90),1.69 (95%CI:1.10-2.58) and 1.72 (95%CI:1.34-2.20)respectively,but with no significant association with perceived susceptibility

  1. The Study of Cardiovascular Risk in Adolescents--ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents.

    Science.gov (United States)

    Bloch, Katia Vergetti; Szklo, Moyses; Kuschnir, Maria Cristina C; Abreu, Gabriela de Azevedo; Barufaldi, Laura Augusta; Klein, Carlos Henrique; de Vasconcelos, Maurício T L; da Veiga, Glória Valéria; Figueiredo, Valeska C; Dias, Adriano; Moraes, Ana Julia Pantoja; Souza, Ana Luiza Lima; de Oliveira, Ana Mayra Andrade; Schaan, Beatriz D'Argord; Tavares, Bruno Mendes; de Oliveira, Cecília Lacroix; Cunha, Cristiane de Freitas; Giannini, Denise Tavares; Belfort, Dilson Rodrigues; Ribas, Dulce Lopes Barboza; Santos, Eduardo Lima; de Leon, Elisa Brosina; Fujimori, Elizabeth; Oliveira, Elizabete Regina Araújo; Magliano, Erika da Silva; Vasconcelos, Francisco de Assis Guedes; Azevedo, George Dantas; Brunken, Gisela Soares; Dias, Glauber Monteiro; Filho, Heleno R Correa; Monteiro, Maria Inês; Guimarães, Isabel Cristina Britto; Faria Neto, José Rocha; Oliveira, Juliana Souza; de Carvalho, Kenia Mara B; Gonçalves, Luis Gonzaga de Oliveira; Santos, Marize M; Muniz, Pascoal Torres; Jardim, Paulo César B Veiga; Ferreira, Pedro Antônio Muniz; Montenegro, Renan Magalhães; Gurgel, Ricardo Queiroz; Vianna, Rodrigo Pinheiro; Vasconcelos, Sandra Mary; da Matta, Sandro Silva; Martins, Stella Maris Seixas; Goldberg, Tamara Beres Lederer; da Silva, Thiago Luiz Nogueira

    2015-02-07

    The Study of Cardiovascular Risk in Adolescents (Portuguese acronym, "ERICA") is a multicenter, school-based country-wide cross-sectional study funded by the Brazilian Ministry of Health, which aims at estimating the prevalence of cardiovascular risk factors, including those included in the definition of the metabolic syndrome, in a random sample of adolescents aged 12 to 17 years in Brazilian cities with more than 100,000 inhabitants. Approximately 85,000 students were assessed in public and private schools. Brazil is a continental country with a heterogeneous population of 190 million living in its five main geographic regions (North, Northeast, Midwest, South and Southeast). ERICA is a pioneering study that will assess the prevalence rates of cardiovascular risk factors in Brazilian adolescents using a sample with national and regional representativeness. This paper describes the rationale, design and procedures of ERICA. Participants answered a self-administered questionnaire using an electronic device, in order to obtain information on demographic and lifestyle characteristics, including physical activity, smoking, alcohol intake, sleeping hours, common mental disorders and reproductive and oral health. Dietary intake was assessed using a 24-hour dietary recall. Anthropometric measures (weight, height and waist circumference) and blood pressure were also be measured. Blood was collected from a subsample of approximately 44,000 adolescents for measurements of fasting glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, glycated hemoglobin and fasting insulin. The study findings will be instrumental to the development of public policies aiming at the prevention of obesity, atherosclerotic diseases and diabetes in an adolescent population.

  2. A cross-sectional study examining the prevalence and risk factors for anti-microbial-resistant generic Escherichia coli in domestic dogs that frequent dog parks in three cities in south-western Ontario, Canada.

    Science.gov (United States)

    Procter, T D; Pearl, D L; Finley, R L; Leonard, E K; Janecko, N; Reid-Smith, R J; Weese, J S; Peregrine, A S; Sargeant, J M

    2014-06-01

    Anti-microbial resistance can threaten health by limiting treatment options and increasing the risk of hospitalization and severity of infection. Companion animals can shed anti-microbial-resistant bacteria that may result in the exposure of other dogs and humans to anti-microbial-resistant genes. The prevalence of anti-microbial-resistant generic Escherichia coli in the faeces of dogs that visited dog parks in south-western Ontario was examined and risk factors for shedding anti-microbial-resistant generic E. coli identified. From May to August 2009, canine faecal samples were collected at ten dog parks in three cities in south-western Ontario, Canada. Owners completed a questionnaire related to pet characteristics and management factors including recent treatment with antibiotics. Faecal samples were collected from 251 dogs, and 189 surveys were completed. Generic E. coli was isolated from 237 of the faecal samples, and up to three isolates per sample were tested for anti-microbial susceptibility. Eighty-nine percent of isolates were pan-susceptible; 82.3% of dogs shed isolates that were pan-susceptible. Multiclass resistance was detected in 7.2% of the isolates from 10.1% of the dogs. Based on multilevel multivariable logistic regression, a risk factor for the shedding of generic E. coli resistant to ampicillin was attending dog day care. Risk factors for the shedding of E. coli resistant to at least one anti-microbial included attending dog day care and being a large mixed breed dog, whereas consumption of commercial dry and home cooked diets was protective factor. In a multilevel multivariable model for the shedding of multiclass-resistant E. coli, exposure to compost and being a large mixed breed dog were risk factors, while consumption of a commercial dry diet was a sparing factor. Pet dogs are a potential reservoir of anti-microbial-resistant generic E. coli; some dog characteristics and management factors are associated with the prevalence of anti

  3. The InterAct Project: An Examination of the Interaction of Genetic and Lifestyle Factors on the Incidence of Type 2 Diabetes in the EPIC Study

    Science.gov (United States)

    Langenberg, C; Sharp, S; Forouhi, NG; Franks, P; Schulze, MB; Kerrison, N; Ekelund, U; Barroso, I; Panico, S; Tormo, M; Spranger, J; Griffin, S; van der Schouw, YT; Amiano, P; Ardanaz, E; Arriola, L; Balkau, B; Barricarte, A; Beulens, JWJ; Boeing, H; Bueno-de-Mesquita, HB; Buijsse, BB; Chirlaque Lopez, MD; Clavel-Chapelon, F; Crowe, FL; de Lauzon-Guillan, B; Deloukas, P; Dorronsoro, M; Drogan, DD; Froguel, P; Gonzalez, C; Grioni, S; Groop, L; Groves, C; Hainaut, P; Halkjaer, J; Hallmans, G; Hansen, T; Kaaks, R; Key, TJ; Khaw, K; Koulman, A; Mattiello, A; Navarro, C; Nilsson, P; Norat, T; Overvad, K; Palla, L; Palli, D; Pedersen, O; Peeters, PH; Quirós, JR; Ramachandran, A; Rodriguez-Suarez, L; Rolandsson, O; Romaguera, D; Romieu, I; Sacerdote, C; Sánchez, M; Sandbaek, A; Slimani, N; Sluijs, I; Spijkerman, AMW; Teucher, B; Tjonneland, A; Tumino, R; van der A, DL; Verschuren, WMM; Tuomilehto, J; Feskens, E; McCarthy, M; Riboli, E; Wareham, NJ

    2014-01-01

    Background Studying gene-lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting important subgroup effects. Adequately powered studies with prospective, unbiased, standardised assessment of key behavioural factors for gene-lifestyle studies are lacking. Objective To establish a type 2 diabetes case-cohort study designed to investigate how genetic and potentially modifiable lifestyle and behavioral factors, particularly diet and physical activity, interact in their influence on the risk of developing type 2 diabetes. Methods Funded by the Sixth European Framework Programme, InterAct consortium partners ascertained and verified incident cases of type 2 diabetes occurring in European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts between 1991 and 2007 from 8 of the 10 EPIC countries. A pragmatic, high sensitivity approach was used for case ascertainment including multiple sources at each EPIC centre, followed by diagnostic verification. Prentice-weighted Cox regression and random effects meta-analyses were used to investigate differences in diabetes incidence by age and sex. Results A total of 12,403 verified incident cases of type 2 diabetes occurred during 3.99 million person-years of follow-up of 340,234 EPIC participants eligible for InterAct. We defined a centre stratified subcohort of 16,154 individuals for comparative analyses. Individuals with incident diabetes that were randomly selected into the subcohort (n=778) were included as cases in the analyses. All prevalent diabetes cases were excluded from the study. InterAct cases were followed-up for an average of 6.9 years, 49.7% were men. Mean baseline age and age at diagnosis were 55.6 and 62.5 years, mean BMI and waist were 29.4 kg/m2 and 102.7 cm in men, and 30.1 kg/m2 and 92.8 cm in women, respectively. Risk of type 2 diabetes increased linearly with age, with an overall hazard ratio (95% CI) of 1.56 (1.48; 1

  4. Study protocol for examining job strain as a risk factor for severe unipolar depression in an individual participant meta-analysis of 14 European cohorts

    DEFF Research Database (Denmark)

    Madsen, Ida E H; Hannerz, Harald; Nyberg, Solja T

    2013-01-01

    BACKGROUND: Previous studies have shown that gainfully employed individuals with high work demands and low control at work (denoted "job strain") are at increased risk of common mental disorders, including depression. Most existing studies have, however, measured depression using self-rated symptom...... scales that do not necessarily correspond to clinically diagnosed depression. In addition, a meta-analysis from 2008 indicated publication bias in the field. METHODS: This study protocol describes the planned design and analyses of an individual participant data meta-analysis, to examine whether job...... using random effects meta-analysis. DISCUSSION: The planned analyses will help clarify whether job strain is associated with an increased risk of clinically diagnosed unipolar depression. As the analysis is based on pre-planned study protocols and an individual participant data meta-analysis, the pooled...

  5. Exchange of Sex for Drugs or Money in Adolescents and Young Adults: An Examination of Sociodemographic Factors, HIV-Related Risk, and Community Context.

    Science.gov (United States)

    Boyer, Cherrie B; Greenberg, Lauren; Chutuape, Kate; Walker, Bendu; Monte, Dina; Kirk, Jennifer; Ellen, Jonathan M

    2017-02-01

    The goal of this research was to examine associations among sociodemographic factors, HIV risk, and community context (e.g., economic insecurity, job training, housing instability, crime victimization, and perceived community norms) in adolescents and young adults who ever exchanged sex for drugs or money. Anonymous survey data were collected using ACASIs at community venues where adolescents and young adults congregate in resource-challenged, STI prevalent, urban, US neighborhoods. Conventional descriptive statistics, Fisher's exact tests, and generalized estimating equations approaches were used to examine associations. Participants (1818, 95.5 % of those screened eligible) were, on average, aged 21.0 years; 42.2 % were males, and 4.6 % were transgender. Almost one-third (32.1 %) identified as gay or lesbian, 18.1 % identified as bisexual; 66.2 % were Black and 21.0 % were Hispanic; 1.3 % was 'living on the street'. A sizeable proportion reported HIV-related risk: 16.3 % exchanged sex, 12.6 % had sex with someone they knew to be HIV-infected, 7.8 % had sex with someone who injected drugs, and 1.3 % injected drugs. Multivariate comparisons identified a number of variables (e.g., being male or transgender, homelessness, sex with a partner who has HIV, STI history, unemployment, job training access, housing instability, crime victimization, perceived community norms) that were significantly associated with exchange of sex (p young adults, particularly as it relates to community context. Longitudinal studies to describe the trajectory of social, health, and physical risks and consequences are needed for development of effective evidence-based prevention strategies.

  6. Barrier Factors to the Completion of Diabetes Education in Korean Diabetic Adult Patients: Korea National Health and Nutrition Examination Surveys 2007-2012.

    Science.gov (United States)

    Kim, Hee-Tae; Lee, Kiheon; Jung, Se Young; Oh, Seung-Min; Jeong, Su-Min; Choi, Yoon-Jung

    2015-09-01

    Diabetes is a disease with high social burdens and is expected to increase gradually. A long-term management is essential for the treatment of diabetes, requiring patient self-cares. Diabetes education is important for such self-cares, but it does not sufficiently take place. In addition, little studies have been conducted on the barriers to the completion of diabetes education. This study, thus, aimed to analyze the factors related to the completion of diabetes education and investigate its barriers. Of 50,405 respondents to the fourth and fifth Korea National Health and Nutrition Examination Survey, a total of 3,820 were selected for the analysis, excluding those aged 29 or younger and those with missing values. The completion of diabetes education was set as a dependent variable and an analysis was made on the factors that affect the dependent variable. A multivariable logistic regression was employed for the analysis. Lower educational level was associated with less diabetes education, and the degree of diabetes education was lower in the group with male, the group that didn't have a family history or was not aware of a family history, the group that was not currently aware of diabetes and the group without a spouse. There was no difference in the completion of diabetes education by underlying diseases, family income level, age, residing area, economic activity status, insurance coverage, smoking, and drinking. Diabetes education is of importance for the treatment and management of diabetes. Currently, however, diabetes education is not sufficiently carried out in Korea. The completion rate of diabetes education was low in male, patients without or not knowing a family history, patients who were not currently aware of their diabetes, patients without a spouse, and patients with low educational level. Therefore, encouraging these patients to take the education will be a more effective approach to increase the completion rate of diabetes education.

  7. Factors and common conditions associated with adolescent dietary supplement use: an analysis of the National Health and Nutrition Examination Survey (NHANES

    Directory of Open Access Journals (Sweden)

    Davis Roger B

    2008-03-01

    Full Text Available Abstract Background Little is known about the prevalence of dietary supplement (DS use in American adolescents. We conducted this study to analyze the prevalence of DS use and factors associated with this use in a national population-based sample. Methods We used data from the 1999 – 2002 National Health and Nutrition Examination Surveys (NHANES for adolescents age 11 to 19. Using weighted logistic regression, we identified demographic and clinical factors associated with the use of any DS, vitamins or minerals, herbs and other DS. Results Among the 5,306 responses representing approximately 36 million Americans 11–19 years old, 27% reported use of one or more DS in the prior month. The most commonly used DS were: multivitamins (16% and vitamin C (6%. In the multivariable analysis, African American [adjusted odds ratio 0.40 (0.31–0.50 95% CI] and Mexican American [0.55 (0.44–0.69] adolescents were less likely to use DS compared with non-Hispanic whites. DS use was more common in those who used prescription medications [1.37 (1.10–1.72] and among those who had a diagnosis of chronic headaches [1.25 (1.04–1.50]. DS use was less common among those reporting fair or poor health status [0.59 (0.40–0.88]. Conclusion Twenty seven percent of American adolescents use DS. DS use is higher among teens that use prescription medications; physicians and pharmacists should be aware of this, ask patients, and check for potential interactions.

  8. Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease among Nonsmokers: Fifth Korea National Health and Nutrition Examination Survey (2010-2012).

    Science.gov (United States)

    Oh, Heeyoung; Lee, Ye-Eun

    2016-12-01

    The purpose of this study was to determine the prevalence of COPD among non-smoking adults, and to investigate the risk factors that affect disease occurrence. The data from the 5th Korea national health and nutrition examination survey (KNHNES) has been used, and 5,489 non-smoking adults aged between 40 to 79 years with diagnosable FEV1/FVC were selected therefrom as the subjects of this study. The prevalence of COPD in non-smokers was observed to be 6.9%. The development of the COPD showed statistically significant difference among groups; males showed about 2.54 times (95% CI: 1.410∼146.612) higher rates compared to females, subjects aged 70-79 showed about 3.08 times (95% CI: 1.823∼11.437) higher rates compared to those aged 40-49, subjects whose education level was elementary school or less showed about 5.36 times (95% CI: 1.341∼21.393) higher rates compared to those who are college or more, and subjects who are middle school showed about 4.72 times (95% CI: 1.374∼16.217) higher rates compared to the college or more. It is confirmed that development of the COPD in non-smokers reach significance. For the prevention of the disease, there is a need to identify COPD-related risk factors in males and the elderly and provide appropriate nursing intervention, and to develop health-related education programs for those with low educational background to take in order to promote the improvement of lung health.

  9. Psychological Status and Associated Factors among Korean Cancer Survivors: a Cross-Sectional Analysis of the Fourth & Fifth Korea National Health and Nutrition Examination Surveys.

    Science.gov (United States)

    Choi, Kyung-Hyun; Park, Sang Min

    2016-07-01

    It is important to assess psychological distress after a diagnosis for cancer survivors, a population with a high risk for psychological distress. The aim of this study is to assess psychological distress among cancer survivors and to clarify the associated factors. In this cross-sectional analysis, data were obtained from standardized questionnaires administered to 1,163 cancer survivors and 49,243 non-cancer survivors who participated in the Fourth and Fifth Korea National Health and Nutrition Examination Survey (2007-2012). We identified the adjusted rates for psychological distress and assessed factors associated with this kind of distress using multivariate logistic regression. Cancer survivors tended to have a higher adjusted rate of psychological distress than the general population. The current depressive symptom rate for cancer survivors was 16.69%, and the adjusted rate for history of depression in cancer survivors was 15.61%. The adjusted rate for higher level of stress was 25.51% in cancer survivors. Among the cancer survivors, younger subjects, female subjects, and those with limited social support were more prone to psychological distress. In addition, current smokers or risky drinkers, those with chronic diseases, and those with a poor self-perception of their health status were also identified as a high-risk group for psychological distress. As the number of cancer survivors has increased, the importance of assessing psychological distress after a cancer diagnosis should be emphasized among all cancer survivors. Further, psychological supportive care interventions for cancer survivors are needed to improve the survival rate and improve their quality of life.

  10. Influence of Lifestyle Factors on Inflammation in Men and Women with Type 2 Diabetes: Results from the National Health and Nutrition Examination Survey, 1999-2004

    Science.gov (United States)

    Jarvandi, Soghra; Davidson, Nicholas O.; Jeffe, Donna B.; Schootman, Mario

    2013-01-01

    Background Type 2 diabetes is associated with low-grade systemic inflammation, increasing the risk for various adverse health outcomes. Purpose Our objective was to investigate the association between C-reactive protein (CRP), a marker for systemic inflammation, and lifestyle factors in a national sample of people with type 2 diabetes. Methods This study analyzed data from 1086 men and women with diabetes, who completed the 1999-2004 NHANES. Lifestyle factors included diet quality, body mass index (BMI), smoking, and physical activity. Results Stratified logistic regression showed that for both men and women, BMI was a strong predictor of elevated CRP after adjusting for age, energy intake, race/ethnicity, medications, diabetes duration, and glycosylated hemoglobin. However, among men, but not among women, the likelihood of elevated CRP increased with lower diet quality and physical inactivity. Conclusions Among people with type 2 diabetes, higher levels of CRP were associated with lower diet quality and physical inactivity among men, and with obesity among both men and women. PMID:22865468

  11. Factors Associated With High Sodium Intake Based on Estimated 24-Hour Urinary Sodium Excretion: The 2009-2011 Korea National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Hong, Jae Won; Noh, Jung Hyun; Kim, Dong-Jun

    2016-03-01

    Although reducing dietary salt consumption is the most cost-effective strategy for preventing progression of cardiovascular and renal disease, policy-based approaches to monitor sodium intake accurately and the understanding factors associated with excessive sodium intake for the improvement of public health are lacking. We investigated factors associated with high sodium intake based on the estimated 24-hour urinary sodium excretion, using data from the 2009 to 2011 Korea National Health and Nutrition Examination Survey (KNHANES). Among 21,199 adults (≥19 years of age) who participated in the 2009 to 2011 KNHANES, 18,000 participants (weighted n = 33,969,783) who completed urinary sodium and creatinine evaluations were analyzed in this study. The 24-hour urinary sodium excretion was estimated using Tanaka equation. The mean estimated 24-hour urinary sodium excretion level was 4349 (4286-4413) mg per day. Only 18.5% (weighted n = 6,298,481/3,396,973, unweighted n = 2898/18,000) of the study participants consumed less the 2000 mg sodium per day. Female gender (P intake ≥50 percentile (P sodium intake, even after adjusting for potential confounders. Senior high school/college graduation in education and managers/professionals in occupation were associated with lower sodium intake (P sodium than those who were normotensive. However, those who receiving treatment for hypertension consumed less sodium than those who were normotensive (P sodium excretion. The logistic regression analysis for the highest estimated 24-hour urinary sodium excretion quartile (>6033 mg/day) using the abovementioned variables as covariates yielded identical results. Our data suggest that age, sex, education level, occupation, total energy intake, obesity, and hypertension management status are associated with excessive sodium intake in Korean adults using nationally representative data. Factors associated with high sodium intake should be considered in policy

  12. To investigate the mechanism about the pathogenic factors including Hhcy, in coronary artery coronary endothelial cell damage mechanism%Hhcy对冠脉内皮细胞损伤机制的临床研究

    Institute of Scientific and Technical Information of China (English)

    张庆成; 张向峰; 韩晓丹

    2016-01-01

    Objective To investigate the mechanism about the pathogenic factors including Hhcy, etc in coronary artery coronary endothelial cell damage mechanism.Methods In this paper, according to coronary angiography examination,select 121 cases of coronary heart disease (CHD) patients. According to the clinical symptom of coronary heart disease group, heartache group 71 cases, acute myocardial infarction group 50 cases. 95 cases of normal healthy subjects were selected as control group. The Hcy, EC, ET, niacin and vitamin B12 were measured.Results In patients with coronary artery stenosis groups of Hcy, EC, ET, niacin, vitamin B12 indicators along with the change of coronary artery stenosis degree change, the more the degree of stenosis serious Hcy, EC, ET, etc indicators increased, the more obvious, in severe stenosis group (P<0.01). Hcy, EC, ET in CHD group significantly increased than the normal control group. The study also found that the level of serum Hcy and EC, Hcy and ET, Hcy and niacin had a positive correlation (r=0.61, r=0.55, r=0.62). Hcy had niacin, Hcy had vitamin B12 had a negative correlation (r=-0.62, r=-0.58).Conclusions The level of Hcy, EC, ET increasing and the level of niacin, vitamin B12 reducing has important significance in coronary artery intimal injury, plaque formation, leading to coronary artery stenosis.%目的:探讨Hhcy等致病因素在冠脉冠脉内皮细胞损伤的机制。方法:本文选择冠心病(CHD)患者121例,根据冠心病临床症状分组,心痛组71例,急性心肌梗塞组50例,选取95例冠状动脉造影等检查为正常健康者作为正常对照组。测定所有受试者同型半胱氨酸(Hcy),内皮细胞(EC),内皮素(ET),烟酸,维生素B12等指标。结果:冠脉狭窄患者各组Hcy,EC,ET、烟酸,维生素B12等指标随冠脉狭窄程度的改变而改变,狭窄程度愈严重Hcy,EC,ET等指标增高越明显(P<0.01)。CHD组Hcy,EC,ET等指标较正

  13. The Effect of Social and Cultural Factors on Ageism: Examination of the Dual-Process Motivational Model of Ideology, Politics, and Prejudice.

    Science.gov (United States)

    Doron, Israel; Kafka, Hanna

    2015-01-01

    This study seeks to examine the applicability of the Dual-Process Model of Ideology, Politics, and Prejudice (DPM) as a theoretical explanatory frame-work to ageism. The study is based on a secondary analysis of the European Social Survey (ESS), a quantitative project established in 2001 that includes 34 European countries. The sample was a representative random sample of the adult population of eight participating countries, and included a total of 19,073 participants. In general, this study's findings point to the fact that no statistically significant correlation exists between the personality variables, whether authoritative or social dominant, and ageism. It appears that the theoretical framework of the DPM model may not be appropriate as a theoretical and explanatory model of the phenomenon of ageism. This may indicate that ageism possibly differs from similar social phenomena, such as sexism and racism, at least in its DPM model basis. More research is needed in this field to better understand the applicability of the DPM model to ageism.

  14. The Relationship between Sport Participation and Chronic Diseases among Men in the USA: An Examination of the Behavioral Risk Factor Surveillance System

    Directory of Open Access Journals (Sweden)

    Jennifer Pharr

    2017-08-01

    Full Text Available Sport participation has been associated with lower rates of chronic diseases when compared to other forms of physical activity (PA among women. However, we do not know if this relationship holds true for men. The purpose of this study was to examine the relationship between sport participation and men’s health and chronic diseases in the USA. This study was a secondary data analysis of the 2015 national Behavioral Risk Factor Surveillance System (BRFSS survey. Participants were questioned extensively about their PA behaviors. Seventy-six different activities were identified and these activities were categorized as sport, conditioning exercise, recreation, or household tasks based upon previously identified categories. Logistic regression was utilized to calculate odds and adjusted odds ratios for chronic diseases based on physical activity category. When compared to men who participated in sport, men in the other PA categories had significantly higher odds for all of the chronic diseases except asthma. After controlling for demographic variables, significant odds remain except for stroke. Higher odds for chronic diseases in the other PA categories indicates that men in these group have a higher risk for chronic diseases than men in the sport category. Because of the potential health improvements related to sports participation, it is important to maintain and increase sport participation for both adolescents and adults.

  15. Where does treatment optimism fit in? Examining factors associated with consistent condom use among people receiving antiretroviral treatment in Rio de Janeiro, Brazil.

    Science.gov (United States)

    Hanif, Homaira; Bastos, Francisco I; Malta, Monica; Bertoni, Neilane; Winch, Peter J; Kerrigan, Deanna

    2014-10-01

    In the era of highly active antiretrovirals, people living with HIV (PLWH) have resumed sexual activity in the context of longer and healthier lives, and thus the chances of transmitting the HIV virus, as well as the potential to be re-infected also increase. HIV treatment optimism has been found to be associated with sexual risk behaviors among PLWH in different settings. A cross sectional survey was conducted to examine the relationship between treatment optimism, safer sex burnout and consistent condom use as well as variables associated with treatment optimism in a sample of PLWH on antiretrovirals (ARVs) in Rio de Janeiro, Brazil (n = 604). Seventy-two percent of participants always used a condom in the last 6 months. Homosexual, bisexual, transexual persons were less likely to use condoms consistently than heterosexuals (AOR .58 CI .42-.78). Those who were treatment optimistic (AOR .46 CI .25-.88) were more likely not use a condom consistently in the past 6 months, as were participants who reported safer sex burnout (AOR .58 CI .36-.90). Sexual orientation, safer sex burnout, and lower education levels were significantly associated with higher treatment optimism in multivariate analysis. Study findings highlight the need to address psychosocial factors such as treatment optimism and safer sex burnout associated with lower consistent condom use among PLWH in Rio de Janeiro, Brazil.

  16. Malignant melanoma of the nasal cavity: a case report with examination of KIT and platelet derived growth factor receptor-α (PDGFRA

    Directory of Open Access Journals (Sweden)

    Tadashi Terada

    2011-10-01

    Full Text Available Although several clinicopathological studies of malignant melanoma of the nasal cavity have been reported, there are no studies of the expression and gene mutation of KIT and platelet derived growth factor receptor-α (PDGFRA in melanoma of the nasal cavity. A 92-year-old Japanese woman consulted to our hospital because of right nasal obstruction and epistaxis. Physical examination and imaging modalities showed a tumor of the right nasal cavity. A biopsy was taken, and it showed malignant epithelioid cells with melanin deposition. Immunohistochemically, the tumor was positive for S100 protein, HMB45, p53, Ki-67 (labeling=20%, KIT and PDGFRA. The tumor was negative for cytokeratins (AE1/3 and CAM5.2. A genetic analysis using PCR-direct sequencing revealed no mutation of KIT gene (exons 9, 11, 13, and 17 or the PDGFRA gene (exons 12 and 18. The pathological diagnosis was primary malignant melanoma of the nasal cavity. The tumor was reduced in size by local resection and chemotherapy (Darthmose regimen: dacarbazine, carmustine, cisplatine, and tamoxifen, and the patient is now alive and free from metastasis 9 months after the first manifestation. In conclusion, the author reported a case of melanoma of the nasal cavity expressing KIT and PDGFRA without gene mutations of KIT and PDGFRA.

  17. Blood mercury can be a factor of elevated serum ferritin: analysis of Korea National Health and Nutrition Examination Survey (KNHANES 2008-2012).

    Science.gov (United States)

    Joo, Nam-Seok; Choi, Young-Hwa; Yeum, Kyung-Jin; Park, Soo-Jung; Choi, Beomhee; Kim, Young-Sang

    2015-03-01

    Serum ferritin as well as blood mercury are reported to be associated with chronic inflammation. However, the relation between serum ferritin and blood mercury has not yet been established. We utilized the Korea National Health and Nutrition Examination Survey (KNHANES, 2008-2012) 10,977 subjects (5433 males and 5544 females). To evaluate the association of serum ferritin and blood mercury cross-sectionally, complex sample analysis was conducted after adjustment for the relevant variables. Serum concentrations of ferritin and blood mercury were higher in males than in females (115.7 ± 1.7 vs. 40.9 ± 0.7 ng/mL and 5.0 ± 0.1 vs. 3.6 ± 0.1 μg/L, respectively). Serum ferritin and blood mercury concentrations had significant correlations in both genders after adjustment (r = 0.062, P serum ferritin according to the tertile of blood mercury (P = 0.007) in males. The adjusted odds ratio of having the highest tertile of serum ferritin in the top tertile of blood mercury in males was 1.52 (95 % confidence interval (CI), 1.05-2.21). Thus, the current study indicates that blood mercury concentration can be a factor for the elevated serum ferritin concentration.

  18. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  19. The Prevalence and Associated Factors of Periodontitis According to Fasting Plasma Glucose in the Korean Adults: The 2012-2013 Korea National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Hong, Jae Won; Noh, Jung Hyun; Kim, Dong-Jun

    2016-04-01

    Although the relationship between diabetes and periodontitis is well established, the association between periodontitis and prediabetes has been investigated less extensively. Furthermore, there has been little research on the prevalence of periodontitis among individuals with prediabetes and diabetes as well as in the overall population using nationally representative data.Among 12,406 adults (≥19 years' old) who participated in the 2012-2013 Korea National Health and Nutrition Examination Survey, a total of 9977 subjects completed oral and laboratory examinations and were included in this analysis. Periodontitis was defined as a community periodontal index score of ≥ 3 according to the World Health Organization criteria. The fasting plasma glucose level was categorized into the following 5 groups: normal fasting glucose (NFG) 1 (periodontitis among the Korean adult population was 24.8% (23.3-26.4%) (weight n = 8,455,952/34,086,014). The unadjusted weighted prevalences of periodontitis were 16.7%, 22.8%, 29.6%, 40.7%, and 46.7% in the NFG 1, NFG 2, IFG 1, IFG 2, and diabetes groups, respectively (P periodontitis increased to 29.7% in the IFG 2 group (P = 0.045) and 32.5% in the diabetes group (P periodontitis with the above-mentioned variables as covariates were 1.42 (95% confidence interval [CI] 1.14-1.77, P = 0.002) in the diabetes group and 1.33 (95% CI 1.01-1.75, P = 0.044) in the IFG 2 group, respectively, compared with the NFG1 group.In conclusion, a higher range of IFG levels as well as diabetes, were positively associated with chronic periodontitis in a representative sample of Korean adults. This study suggests that individuals with a higher range of IFG levels before diabetes are at risk of periodontitis, and may benefit from dental screening.

  20. Investigating students’ attitude towards the importance of factors included in the teaching evaluation forms of School of Public Health of Shahid Sadoughi University of Medical Sciences in 2010-2011

    Directory of Open Access Journals (Sweden)

    M. H Dehghani Tafti

    2012-11-01

    Full Text Available Introduction: students’ attitudes about teaching methodology have been widely recognised as a valid tool of evaluating teaching activities of faculty members. This study aims to determine the importance of the factors included in the teaching evaluation, from the students’ point of view. Methods: This is a cross-sectional study. Using a random cluster sampling, 332 students of the school of public health of Shahid Sadoughi University were selected .To collect data, a questionnaire containing three partswere used. These were demographic items, teachers’ evaluation (14 items and self-evaluation (4 items. Results: The students (80% scoredpersonal characteristics more. Among different fields of study, those studying occupational health scored the factorsless than others, and those studying at masters level scored them more than others.   The results indicated that there are significant correlation between age, marital status, and employment status of the students and the total average score.   The students scored the self-evaluation items more than 60%, There was a significant correlation between the average scores of evaluation and self-evaluation items. The students at bachelor level scored the factor more than masters students. Conclusion: The students’ focus on personal characteristics of teachers was remarkable. There is a need to revise the process of academics’ recruitment based on these findings. There is also a need to review the items included in evaluation forms of the school.

  1. Association of daily physical activity level with health-related factors by gender and age-specific differences among Korean adults based on the sixth (2014-2015) Korea National Health and Nutrition Examination Survey.

    Science.gov (United States)

    Chung, Nana; Park, Hun-Young; Park, Mi-Young; Hwang, Yoon-Young; Lee, Chi-Ho; Han, Jin-Soo; So, Jaemoo; Kim, Jisu; Park, Jonghoon; Lim, Kiwon

    2017-06-30

    This study examined the effects of daily physical activity level on health-related factors according to gender and identified age-specific differences among Korean adults. Using data from the Korea National Health and Nutrition Examination Survey VI (2014-2015), we selected adults aged 19-64 years who participated in both a health examination and health interview survey. The study included 6,457 participants 19-64 years of age (2,611 men, 3,846 women). Assessment of the differences in health-related factors according to age and physical activity in men and women by repeated two-way analysis of variance (ANOVA) revealed significant interaction effects on total cholesterol (TC) and triglyceride (TG) levels and diastolic blood pressure (DBP) in male participants, but there were no significant interaction effects for any health-related factors in female participants. The group of female participants aged 40-64 years with daily physical activity levels over 200 kcal showed a significantly increased prevalence of 46% for dyslipidemia compared to that in female participants with daily physical activity levels below 200 kcal. Physical activity was positively correlated with weight and high-density lipoprotein cholesterol (HDL-C) levels in men 19-39 years of age, compared to weight, waist circumference (WC), body mass index (BMI), and DBP in men 40-64 years of age, and weight, WC, BMI, glycated hemoglobin (HbA1c) and triglyceride (TG) levels in women 19-39 years of age. In women 40- 64 years of age, physical activity was especially significantly positively correlated with weight, BMI, HDL-C and negatively correlated with fasting glucose and TG levels. In male and female participants, the 40-64-year age group showed negative results for health-related factors compared to those in the 19-39-year age group. The higher the weight, WC, BMI, the higher is the physical activity level. Physical activity levels were significantly positively correlated with health-related variables.

  2. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? Survey Item Bank Search for: Visual Impairment, Including Blindness Links updated, April 2017 En ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  3. Examination of factors dominating the sediment-water diffusion flux of DDT-related compounds measured by passive sampling in an urbanized estuarine bay.

    Science.gov (United States)

    Feng, Yan; Wu, Chen-Chou; Bao, Lian-Jun; Shi, Lei; Song, Lin; Zeng, Eddy Y

    2016-12-01

    The fate of hydrophobic organic compounds in aquatic environment are largely determined by their exchange at sediment-water interface, which is highly dynamic and subject to rapidly evolving environmental conditions. In turn, environmental conditions may be governed by both physicochemical parameters and anthropogenic events. To examine the importance of various impact factors, passive sampling devices were deployed at the seafloor of Hailing Bay, an urbanized estuarine bay in Guangdong Province of South China to measure the sediment-water diffusion fluxes of several metabolites of dichlorodiphenyltrichloroethane (DDT), p,p'-DDE, p,p'-DDD and o,p'-DDD. The physicochemical properties of water (temperature, pH, salinity and dissolved oxygen) and surface sediment (sediment organic matter, physical composition, pH, water content, colony forming unit and catalase activity) were also measured. The results showed that the diffusion fluxes of o,p'-DDD, p,p'-DDD and p,p'-DDE at sites A1 and A2 near a fishing boat maintenance facility ranged from 0.42 to 4.73 ng m(-2) d(-1) (from sediment to overlying water), whereas those at offshore sites varied between -0.03 and -3.02 ng m(-2) d(-1) (from overlying water to sediment), implicating A1 and A2 as the sources of the target compounds. The distribution patterns of the diffusion fluxes of the target compounds were different from those of water and sediment parameters (water temperature, salinity, sediment texture, pH, colony forming unit and catalase activity) at six sampling sites. This finding suggested that none of these parameters were critical in dictating the sediment-water diffusion fluxes. Besides, decreases in the contents of kerogen and black carbon by 6.7% and 11% would enhance the diffusion fluxes of the target compounds by 11-14% and 12-23%, respectively, at site A1, indicating that kerogen and black carbon were the key factors in mediating the sediment-water diffusion fluxes of DDT-related compounds in field

  4. Immunohistochemical examination of effects of kefir, koumiss and commercial probiotic capsules on platelet derived growth factor-c and platelet derived growth factor receptor-alpha expression in mouse liver and kidney.

    Science.gov (United States)

    Bakir, B; Sari, E K; Aydin, B D; Yildiz, S E

    2015-04-01

    We investigated using immunohistochemistry the effects of kefir, koumiss and commercial probiotic capsules on the expression of platelet derived growth factor-c (PDGF-C) and platelet derived growth factor receptor-alpha (PDGFR-α) in mouse liver and kidney. Mice were assigned to four groups: group 1 was given commercial probiotic capsules, group 2 was given kefir, group 3 was given koumiss and group 4 was untreated. After oral administration for 15 days, body weights were recorded and liver and kidney tissue samples were obtained. Hematoxylin and eosin staining was used to examine histology. PDGF-C and PDGFR-α in liver and kidney were localized using the streptavidin-biotin peroxidase complex method (ABC). We found that the weights of the mice in the kefir, koumiss and commercial probiotic capsules groups increased compared to the control group. No differences in liver and kidney histology were observed in any of the experimental groups. Kefir, koumiss and the commercial probiotic preparation increased PDGF-C and PDGFR-α expression.

  5. Examining the Relations Among the DSM-5 Alternative Model of Personality, the Five-Factor Model, and Externalizing and Internalizing Behavior.

    Science.gov (United States)

    Sleep, Chelsea E; Hyatt, Courtland S; Lamkin, Joanna; Maples-Keller, Jessica L; Miller, Joshua D

    2017-01-26

    Given long-standing criticisms of the DSM's reliance on categorical models of psychopathology, including the poor reliability and validity of personality-disorder diagnoses, the American Psychiatric Association (APA) published an alternative model (AM) of personality disorders in Section III of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; APA, 2013), which, in part, comprises 5 pathological trait domains based on the 5-factor model (FFM). However, the empirical profiles and discriminant validity of the AM traits remain in question. We recruited a sample of undergraduates (N = 340) for the current study to compare the relations found between a measure of the DSM-5 AM traits (i.e., the Personality Inventory for DSM-5; PID-5; Krueger, Derringer, Markon, Watson, & Skodol, 2012) and a measure of the FFM (i.e., the International Personality Item Pool; IPIP; Goldberg, 1999) in relation to externalizing and internalizing symptoms. In general, the domains from the 2 measures were significantly related and demonstrated similar patterns of relations with these criteria, such that Antagonism/low Agreeableness and Disinhibition/low Conscientiousness were related to externalizing behaviors, whereas Negative Affectivity/Neuroticism was most significantly related to internalizing symptoms. However, the PID-5 demonstrated large interrelations among its domains and poorer discriminant validity than the IPIP. These results provide additional support that the conception of the trait model included in the DSM-5 AM is an extension of the FFM, but highlight some of the issues that arise due to the PID-5's more limited discriminant validity. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  6. Experimental Determination of the Recovery Factor and Analytical Solution of the Conical Flow Field for a 20 deg Included Angle Cone at Mach Numbers of 4.6 and 6.0 and Stagnation Temperatures to 2600 degree R

    Science.gov (United States)

    Pfyl, Frank A.; Presley, Leroy L.

    1961-01-01

    The local recovery factor was determined experimentally along the surface of a thin-walled 20 deg included angle cone for Mach numbers near 6.0 at stagnation temperatures between 1200 deg R and 2600 deg R. In addition, a similar cone configuration was tested at Mach numbers near 4.5 at stagnation temperatures of approximately 612 deg R. The local Reynolds number based on flow properties at the edge of the boundary layer ranged between 0.1 x 10(exp 4) and 3.5 x 10(exp 4) for tests at temperatures above 1200 deg R and between 6 x 10(exp 4) and 25 x 10(exp 4) for tests at temperatures near 612 deg R. The results indicated, generally, that the recovery factor can be predicted satisfactorily using the square root of the Prandtl number. No conclusion could be made as to the necessity of evaluating the Prandtl number at a reference temperature given by an empirical equation, as opposed to evaluating the Prandtl number at the wall temperature or static temperature of the gas at the cone surface. For the tests at temperatures above 1200 deg R (indicated herein as the tests conducted in the slip-flow region), two definite trends in the recovery data were observed - one of increasing recovery factor with decreasing stagnation pressure, which was associated with slip-flow effects and one of decreasing recovery factor with increasing temperature. The true cause of the latter trend could not be ascertained, but it was shown that this trend was not appreciably altered by the sources of error of the magnitude considered herein. The real-gas equations of state were used to determine accurately the local stream properties at the outer edge of the boundary layer of the cone. Included in the report, therefore, is a general solution for the conical flow of a real gas using the Beattie-Bridgeman equation of state. The largest effect of temperature was seen to be in the terms which were dependent upon the internal energy of the gas. The pressure and hence the pressure drag terms were

  7. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  8. Cytogenetic examination

    OpenAIRE

    2015-01-01

    Cytogenetic examination on six normal persons, four men and two women, was carried out using a technique proposed by Dutrillaux with slight modification. Five drops of blood were taken from a peripheral vessel and was incubated on a PHA (phytohemarglutinine)-containing medium at 37°C for about 72 hours. Cell division was blocked by adding colchicine solution, an antimitotic agent, into this medium. A mixture of distilled water, magnesium chloride, hyaluronidase, and goat serum was used as hy...

  9. Internalized Homophobia and Drug Use in a National Cohort of Gay and Bisexual Men: Examining Depression, Sexual Anxiety, and Gay Community Attachment as Mediating Factors.

    Science.gov (United States)

    Moody, Raymond L; Starks, Tyrel J; Grov, Christian; Parsons, Jeffrey T

    2017-06-12

    The minority stress process of internalized homophobia (IH) has been associated with a range of adverse health outcomes among gay and bisexual men (GBM). However, evidence is mixed regarding the effect of IH on drug use, suggesting the potential role of multiple mediated pathways. Researchers have linked depression, sexual anxiety, and gay community attachment with IH. Depression, sexual anxiety, and gay community attachment have also been linked with drug use and drug-related problems suggesting potential mediating roles. A U.S. national sample of 1071 HIV-negative GBM completed at-home surveys, including measures of sociodemographic characteristics, IH, depression, sexual anxiety, gay community attachment, and drug use and associated problems. Adjusting for sociodemographic characteristics, depression mediated the association between IH and recent drug use. IH was positively associated with depression, and depression was positively associated with recent drug use. Gay community attachment partially mediated drug-related problems. IH had a positive direct association with drug-related problems and a negative direct association with gay community attachment. Gay community attachment had a positive association with drug-related problems. IH was positively associated with sexual anxiety, but sexual anxiety was not associated with either drug outcome. Efforts to reduce IH among HIV-negative GBM are likely to have a positive impact on mental health problems, as well as reduce risk for drug use and drug-related problems. Gay communities could provide the social support necessary for reducing IH; however, emphasis on community level interventions that address factors that increase risk for drug-related problems remains important.

  10. Family Engagement in Literacy Activities: Revised Factor Structure for the Familia--An Instrument Examining Family Support for Early Literacy Development

    Science.gov (United States)

    Buhs, Eric S.; Welch, Greg; Burt, Jennifer; Knoche, Lisa

    2011-01-01

    This study evaluated a data-set drawn using "The Familia"--a measure originally developed to evaluate shared-reading activities. A newly developed set of conceptual supports and a confirmatory factor analysis (CFA) were applied to a new factor structure/model. Data were drawn from 219 young children and their families (mean age = 43…

  11. Family Engagement in Literacy Activities: Revised Factor Structure for the Familia--An Instrument Examining Family Support for Early Literacy Development

    Science.gov (United States)

    Buhs, Eric S.; Welch, Greg; Burt, Jennifer; Knoche, Lisa

    2011-01-01

    This study evaluated a data-set drawn using "The Familia"--a measure originally developed to evaluate shared-reading activities. A newly developed set of conceptual supports and a confirmatory factor analysis (CFA) were applied to a new factor structure/model. Data were drawn from 219 young children and their families (mean age = 43 months)…

  12. Family Engagement in Literacy Activities: Revised Factor Structure for the Familia--An Instrument Examining Family Support for Early Literacy Development

    Science.gov (United States)

    Buhs, Eric S.; Welch, Greg; Burt, Jennifer; Knoche, Lisa

    2011-01-01

    This study evaluated a data-set drawn using "The Familia"--a measure originally developed to evaluate shared-reading activities. A newly developed set of conceptual supports and a confirmatory factor analysis (CFA) were applied to a new factor structure/model. Data were drawn from 219 young children and their families (mean age = 43…

  13. 4种无创性检查及其组合对冠心病诊断的辅助作用研究%Noninvasive examinations plus cfinical risk factors for auxiliary diagnosis of coronary heart disease

    Institute of Scientific and Technical Information of China (English)

    刘亚斌; 韩雅玲; 荆全民; 王效增; 李毅; 张磊; 霍勇; 张岩

    2011-01-01

    Objective To evaluate values of non-invasive examinations plus clinical risk factors in auxiliary diagnosis of coronary heart disease. Methods The investigation was conducted in patients who had first undergone CAG from January 2001 through March 2007 in 20 top Chinese hospitals. In the auxiliary diagnosis of coronary heart disease, non-invasive examinations, including Holter, treadmill exercise test ( TET) , radionuclide myocardial perfusion imaging (MPI) ,multislice spiral computed tomography (MSCT) and their combinations, were used with additional consideration of common clinical risk factors. The sensitivities and specificities of different diagnostic strategies were determined in the auxiliary diagnosis of coronary heart disease. Results The sensitivities of different combinations of non-invasive examinations ranged from 56. 02% to 87. 43% , the specificities ranged from 36. 13% to 89. 66% ,the positive predictive rates ranged from 58. 83% to 97. 73% , and the negative predictive rates ranged from 30. 21% to 73. 36%. The addition of clinical risk factors into the auxiliary diagnosis was not found to improve the discrimination capability. Conclusion Combination of non-invasive examinations can be used as a basic and significant diagnostic method for coronary artery disease, particularly the combination of Holter and MSCT,in various levels of hospitals. Clinical risk factors may not contribute to the improved discrimination capability in auxiliary diagnosis of coronary heart disease.%目的 评价几种无创性检查联合临床危险因素对冠心病诊断的辅助价值.方法 选择2001年1月至2007年3月在全国20家三级甲等医院心内科住院疑诊冠心病并初次行诊断性冠状动脉造影(CAG)的患者.纳入常见的临床危险因素后,评价4种无创性检查(包括动态心电图、负荷心电图、负荷核素心肌显像、冠脉CT)及其组合对冠心病诊断的敏感度、特异度.结果 无创性检查组合在冠心

  14. Re-Examining the Dimensions of Obligatory Exercise

    Science.gov (United States)

    Duncan, Lindsay R.; Hall, Craig R.; Fraser, Shawn N.; Rodgers, Wendy M.; Wilson, Philip M.; Loitz, Christina C.

    2012-01-01

    The authors examined the factor structure and psychometric properties of the Obligatory Exercise Questionnaire using exploratory factor analyses (Study 1), and confirmatory factor analyses (Study 2). The relationships between obligatory exercise and other psychological variables including: motivation, subjective well-being, physical self-concept,…

  15. Re-Examining the Dimensions of Obligatory Exercise

    Science.gov (United States)

    Duncan, Lindsay R.; Hall, Craig R.; Fraser, Shawn N.; Rodgers, Wendy M.; Wilson, Philip M.; Loitz, Christina C.

    2012-01-01

    The authors examined the factor structure and psychometric properties of the Obligatory Exercise Questionnaire using exploratory factor analyses (Study 1), and confirmatory factor analyses (Study 2). The relationships between obligatory exercise and other psychological variables including: motivation, subjective well-being, physical self-concept,…

  16. Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation.

    Science.gov (United States)

    Carruthers, Nicholas J; Stemmer, Paul M; Chen, Ben; Valeriote, Frederick; Gao, Xiaohua; Guatam, Subhash C; Shaw, Jiajiu

    2017-09-15

    UTL-5g is a novel small-molecule TNF-alpha modulator. It reduces cisplatin-induced side effects by protecting kidney, liver, and platelets, thereby increasing tolerance for cisplatin. UTL-5g also reduces radiation-induced acute liver toxicity. The mechanism of action for UTL-5g is not clear at the present time. A phosphoproteomic analysis to a depth of 4943 phosphopeptides and a luminescence-based transcription factor activity assay were used to provide complementary analyses of signaling events that were disrupted by UTL-5g in RAW 264.7 cells. Transcriptional activity downstream of the interferon gamma, IL-6, type 1 Interferon, TGF-β, PKC/Ca(2+) and the glucocorticoid receptor pathways were disrupted by UTL-5g. Phosphoproteomic analysis indicated that hyperphosphorylation of proteins involved in actin remodeling was suppressed by UTL-5g (gene set analysis, FDR 5g. This global characterization of UTL-5g activity in a macrophage cell line discovered that it disrupts selected aspects of LPS signaling including Stat3 activation and actin remodeling providing new insight on how UTL-5g acts to reduce cisplatin-induced side effects. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Examination Syllabus Comparisons.

    Science.gov (United States)

    Mallatratt, J. L.

    1983-01-01

    A study was conducted based on an analysis of computer study courses leading to CSE and 0-level examinations. Several findings are discussed and questions about future developments are raised. Syllabus content (including history, hardware, basic computer science, programming, applications, and implications), format, and examinations are among the…

  18. Examination Syllabus Comparisons.

    Science.gov (United States)

    Mallatratt, J. L.

    1983-01-01

    A study was conducted based on an analysis of computer study courses leading to CSE and 0-level examinations. Several findings are discussed and questions about future developments are raised. Syllabus content (including history, hardware, basic computer science, programming, applications, and implications), format, and examinations are among the…

  19. An Examination of Socio-Demographic Factors and Their Influence on Health Behaviors among International Students in the Texas State University System

    Science.gov (United States)

    Msengi, Clementine Mukeshimana

    2012-01-01

    The number of international students attending higher education in the United States continues to grow (McLachlan & Justice, 2009). International students face several challenges while studying in the United States, some of which are health challenges (Zysberg, 2005). The purpose of this study was to examine the influence of various…

  20. <