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Sample records for factor xii fxii

  1. Evaluation of thromboelastography in two factor XII-deficient cats.

    Science.gov (United States)

    Blois, Shauna L; Holowaychuk, Marie K; Wood, R Darren

    2015-01-01

    The current report describes thromboelastography (TEG) findings in two cats with factor XII (FXII) deficiency. The first cat was diagnosed with bilateral perinephric pseudocysts; hemostatic testing was performed prior to performing renal aspirates. The second cat was healthy; hemostatic testing was performed prior to inclusion into a research project. Both cats had markedly prolonged partial thromboplastin times and hypocoagulable TEG tracings when samples were activated with kaolin. However, when tissue factor (TF) was used to activate the sample, both cats had normal-to-hypercoagulable TEG tracings. The cats each had a subnormal FXII level. TEG is becoming widely used to investigate hemostasis in veterinary patients, and TEG results in cats with FXII deficiency have not been previously reported. FXII deficiency is the most common hereditary hemostatic defect in cats. While FXII deficiency does not lead to in vivo hemorrhagic tendencies, it can lead to marked prolongation in activated partial thromboplastin and activated clotting times, and cannot be differentiated from true hemorrhagic diatheses without measuring individual factor activity. With the increased use of TEG to evaluate hemostasis in veterinary patients, it is important to recognize the effects of FXII deficiency on this testing modality. The finding of a hypocoagulable kaolin-activated TEG tracing and a concurrent normal TF-activated TEG tracing in samples should prompt clinicians to consider ruling out FXII deficiency.

  2. Evaluation of thromboelastography in two factor XII-deficient cats

    Directory of Open Access Journals (Sweden)

    Shauna L Blois

    2015-05-01

    Full Text Available Case summary The current report describes thromboelastography (TEG findings in two cats with factor XII (FXII deficiency. The first cat was diagnosed with bilateral perinephric pseudocysts; hemostatic testing was performed prior to performing renal aspirates. The second cat was healthy; hemostatic testing was performed prior to inclusion into a research project. Both cats had markedly prolonged partial thromboplastin times and hypocoagulable TEG tracings when samples were activated with kaolin. However, when tissue factor (TF was used to activate the sample, both cats had normal-to-hypercoagulable TEG tracings. The cats each had a subnormal FXII level. Relevance and novel information TEG is becoming widely used to investigate hemostasis in veterinary patients, and TEG results in cats with FXII deficiency have not been previously reported. FXII deficiency is the most common hereditary hemostatic defect in cats. While FXII deficiency does not lead to in vivo hemorrhagic tendencies, it can lead to marked prolongation in activated partial thromboplastin and activated clotting times, and cannot be differentiated from true hemorrhagic diatheses without measuring individual factor activity. With the increased use of TEG to evaluate hemostasis in veterinary patients, it is important to recognize the effects of FXII deficiency on this testing modality. The finding of a hypocoagulable kaolin-activated TEG tracing and a concurrent normal TF-activated TEG tracing in samples should prompt clinicians to consider ruling out FXII deficiency.

  3. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

    Science.gov (United States)

    Göbel, Kerstin; Pankratz, Susann; Asaridou, Chloi-Magdalini; Herrmann, Alexander M.; Bittner, Stefan; Merker, Monika; Ruck, Tobias; Glumm, Sarah; Langhauser, Friederike; Kraft, Peter; Krug, Thorsten F.; Breuer, Johanna; Herold, Martin; Gross, Catharina C.; Beckmann, Denise; Korb-Pap, Adelheid; Schuhmann, Michael K.; Kuerten, Stefanie; Mitroulis, Ioannis; Ruppert, Clemens; Nolte, Marc W.; Panousis, Con; Klotz, Luisa; Kehrel, Beate; Korn, Thomas; Langer, Harald F.; Pap, Thomas; Nieswandt, Bernhard; Wiendl, Heinz; Chavakis, Triantafyllos; Kleinschnitz, Christoph; Meuth, Sven G.

    2016-01-01

    Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity. Here we identify coagulation factor XII (FXII), the initiator of the intrinsic coagulation cascade and the kallikrein–kinin system, as a specific immune cell modulator. High levels of FXII activity are present in the plasma of MS patients during relapse. Deficiency or pharmacologic blockade of FXII renders mice less susceptible to experimental autoimmune encephalomyelitis (a model of MS) and is accompanied by reduced numbers of interleukin-17A-producing T cells. Immune activation by FXII is mediated by dendritic cells in a CD87-dependent manner and involves alterations in intracellular cyclic AMP formation. Our study demonstrates that a member of the plasmatic coagulation cascade is a key mediator of autoimmunity. FXII inhibition may provide a strategy to combat MS and other immune-related disorders. PMID:27188843

  4. Factor XII (Hageman factor) deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000545.htm Factor XII (Hageman factor) deficiency To use the sharing features on this ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  5. Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation

    NARCIS (Netherlands)

    Stroo, Ingrid; Zeerleder, Sacha; Ding, Chao; Luken, Brenda M.; Roelofs, Joris J. T. H.; de Boer, Onno J.; Meijers, Joost C. M.; Castellino, Francis J.; van 't Veer, Cornelis; van der Poll, Tom

    2017-01-01

    Bacterial pneumonia, the most common cause of sepsis, is associated with activation of coagulation. Factor XI (FXI), the key component of the intrinsic pathway, can be activated via factor XII (FXII), part of the contact system, or via thrombin. To determine whether intrinsic coagulation is involved

  6. Transforming growth factor-β1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts.

    Science.gov (United States)

    Jablonska, Ewa; Markart, Philipp; Zakrzewicz, Dariusz; Preissner, Klaus T; Wygrecka, Malgorzata

    2010-04-09

    Coagulation factor XII (FXII) is a liver-derived serine protease involved in fibrinolysis, coagulation, and inflammation. The regulation of FXII expression is largely unknown. Transforming growth factor-beta1 (TGF-beta1) is a multifunctional cytokine that has been linked to several pathological processes, including tissue fibrosis by modulating procoagulant and fibrinolytic activities. This study investigated whether TGF-beta1 may regulate FXII expression in human lung fibroblasts. Treatment of human lung fibroblasts with TGF-beta1 resulted in a time-dependent increase in FXII production, activation of p44/42, p38, JNK, and Akt, and phosphorylation and translocation into the nucleus of Smad3. However, TGF-beta1-induced FXII expression was repressed only by the JNK inhibitor and JNK and Smad3 antisense oligonucleotides but not by MEK, p38, or phosphoinositide 3-kinase blockers. JNK inhibition had no effect on TGF-beta1-induced Smad3 phosphorylation, association with Smad4, and its translocation into the nucleus but strongly suppressed Smad3-DNA complex formation. FXII promoter analysis revealed that the -299/+1 region was sufficient for TGF-beta1 to induce FXII expression. Sequence analysis of this region detected a potential Smad-binding element at position -272/-269 (SBE-(-272/-269)). Chromatin immunoprecipitation and streptavidin pulldown assays demonstrated TGF-beta1-dependent Smad3 binding to SBE-(-272/-269). Mutation or deletion of SBE-(-272/-269) substantially reduced TGF-beta1-mediated activation of the FXII promoter. Clinical relevance was demonstrated by elevated FXII levels and its co-localization with fibroblasts in the lungs of patients with acute respiratory distress syndrome. Our results show that JNK/Smad3 pathway plays a critical role in TGF-beta1-induced FXII expression in human lung fibroblasts and implicate its possible involvement in pathological conditions characterized by elevated TGF-beta1 levels.

  7. Identification of Genetic Defects Underlying FXII Deficiency in Four Unrelated Chinese Patients.

    Science.gov (United States)

    Yang, Lihong; Wang, Yingyu; Zhou, Jianpin; Cheng, Xiaoli; Hao, Xiuping; Xie, Haixiao; Jin, Yanhui; Wang, Mingshan

    2016-01-01

    Congenital factor XII (FXII) dexFB01;ciency is a rare autosomal recessive disorder, characterized by a great variability in its clinical manifestations. In this study, we screened for mutations in the F12 gene of 4 unrelated patients with FXII coagulant activity Gly542 Ser), 1 insertion (7142insertC) and 2 deletions (5741-5742 delCA and 6753-6755delACA), were identixFB01;ed on the F12 gene. Three of them (Gly341Arg, 5741-5742delCA and 6753-6755delACA) are reported here for the first time. Computer-based algorithms predicted these missense mutations to be deleterious. This study has increased our knowledge of the mutational spectrum underlying FXII deficiency. © 2016 S. Karger AG, Basel.

  8. Radioimmunoassay of human Hageman factor (factor XII)

    International Nuclear Information System (INIS)

    Saito, H.; Ratnoff, O.D.; Pensky, J.

    1976-01-01

    A specific, sensitive, and reproducible radioimmunoassay for human Hageman factor (HF, factor XII) has been developed with purified human HF and monospecific rabbit antibody. Precise measurements of HF antigen were possible for concentrations as low as 0.1 percent of that in normal pooled plasma. A good correlation (correlation coefficient = 0.82) existed between the titers of HF measured by clot-promoting assays and radioimmunoassays among 42 normal adults. Confirming earlier studies, HF antigen was absent in Hageman trait plasma, but other congenital deficient plasmas, including those of individuals with Fletcher trait and Fitzgerald trait, contained normal amounts of HF antigen. HF antigen was reduced in the plasmas of patients with disseminated intravascular coagulation or advanced liver cirrhosis, but it was normal in those of patients with chronic renal failure or patients under treatment with warfarin. HF antigen was detected by this assay in plasmas of primates, but not detectable in plasmas of 11 nonprimate mammalian and one avian species

  9. Factor XI and XII as antithrombotic targets.

    Science.gov (United States)

    Müller, Felicitas; Gailani, David; Renné, Thomas

    2011-09-01

    Arterial and venous thrombosis are major causes of morbidity and mortality, and the incidence of thromboembolic diseases increases as a population ages. Thrombi are formed by activated platelets and fibrin. The latter is a product of the plasma coagulation system. Currently available anticoagulants such as heparins, vitamin K antagonists and inhibitors of thrombin or factor Xa target enzymes of the coagulation cascade that are critical for fibrin formation. However, fibrin is also necessary for terminating blood loss at sites of vascular injury. As a result, anticoagulants currently in clinical use increase the risk of bleeding, partially offsetting the benefits of reduced thrombosis. This review focuses on new targets for anticoagulation that are associated with minimal or no therapy-associated increased bleeding. Data from experimental models using mice and clinical studies of patients with hereditary deficiencies of coagulation factors XI or XII have shown that both of these clotting factors are important for thrombosis, while having minor or no apparent roles in processes that terminate blood loss (hemostasis). Hereditary deficiency of factor XII (Hageman factor) or factor XI, plasma proteases that initiate the intrinsic pathway of coagulation, impairs thrombus formation and provides protection from vascular occlusive events, while having a minimal impact on hemostasis. As the factor XII-factor XI pathway contributes to thrombus formation to a greater extent than to normal hemostasis, pharmacological inhibition of these coagulation factors may offer the exciting possibility of anticoagulation therapies with minimal or no bleeding risk.

  10. Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system.

    Directory of Open Access Journals (Sweden)

    Shannon L Taylor

    Full Text Available Hemorrhagic fever with renal syndrome (HFRS and hantavirus pulmonary syndrome (HPS are diseases caused by hantavirus infections and are characterized by vascular leakage due to alterations of the endothelial barrier. Hantavirus-infected endothelial cells (EC display no overt cytopathology; consequently, pathogenesis models have focused either on the influx of immune cells and release of cytokines or on increased degradation of the adherens junction protein, vascular endothelial (VE-cadherin, due to hantavirus-mediated hypersensitization of EC to vascular endothelial growth factor (VEGF. To examine endothelial leakage in a relevant in vitro system, we co-cultured endothelial and vascular smooth muscle cells (vSMC to generate capillary blood vessel-like structures. In contrast to results obtained in monolayers of cultured EC, we found that despite viral replication in both cell types as well as the presence of VEGF, infected in vitro vessels neither lost integrity nor displayed evidence of VE-cadherin degradation. Here, we present evidence for a novel mechanism of hantavirus-induced vascular leakage involving activation of the plasma kallikrein-kinin system (KKS. We show that incubation of factor XII (FXII, prekallikrein (PK, and high molecular weight kininogen (HK plasma proteins with hantavirus-infected EC results in increased cleavage of HK, higher enzymatic activities of FXIIa/kallikrein (KAL and increased liberation of bradykinin (BK. Measuring cell permeability in real-time using electric cell-substrate impedance sensing (ECIS, we identified dramatic increases in endothelial cell permeability after KKS activation and liberation of BK. Furthermore, the alterations in permeability could be prevented using inhibitors that directly block BK binding, the activity of FXIIa, or the activity of KAL. Lastly, FXII binding and autoactivation is increased on the surface of hantavirus-infected EC. These data are the first to demonstrate KKS activation

  11. Association of FXII 5’UTR 46C>T polymorphism with FXII activity and risk of thrombotic disease

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    Parisa Rasighaemi

    2010-03-01

    Full Text Available Objective: Thrombotic diseases are caused by genetic and environmental factors. There are a number of well-characterized genetic defects that lead to increased risk of thrombosis. Results from previous studies have indicated that FXII is involved in the pathogenesis of thrombophilic diseases. However, the results in this regard are highly controversial. One of the most important determinants of Plasma FXII level is 46CgT polymorphism in the FXII gene. In the present study, the risk of thrombophilic diseases related to this polymorphism was investigated in a case-control study. Material and Methods: One hundred and sixty subjects were studied: 120 patients diagnosed with thrombophilia (96 venous thromboembolism, 24 arterial thrombosis, and 40 age-gender-matched controls. For each subject, FXII activity level was measured by a one-step clotting assay with FXII-deficient plasma, and 46CγT polymorphism was genotyped using a restriction fragment length polymorphism (RFLP method. Results: In this study, the previous observation that individuals with different genotypes for the 46 CγT polymorphism show significant differences in FXII activity levels was confirmed. Most importantly, FXII activity ≤68% was associated with an increased risk of venous thrombosis with an adjusted odds ratio (OR of 4.7 (95% confidence interval [CI]: 1.03-21.1, p=0.04. However, it was not a risk factor for arterial thrombosis with adjusted OR of 5 (95% CI: 0.91-27.1, p=0.09. In CT and TT genotype, the adjusted ORs were 2 (95% CI: 0.9-4.4, p=0.11 and 2.3 (95% CI: 0.45-11, p=0.48, respectively, for patients with venous thrombosis compared with the controls. Similarly, the adjusted ORs in arterial thrombosis were 1.2 (95% CI: 0.4-3.6, p=0.76 for CT and 1.8 (95% CI: 0.2-14.9, p=0.59 for TT genotype. Thus, we did not find any association of the mutated T allele in the heterozygous or homozygous state with an increased risk of venous or arterial thrombosis. Conclusion: Lower

  12. Factor XII-independent activation of the bradykinin-forming cascade

    DEFF Research Database (Denmark)

    Joseph, Kusumam; Tholanikunnel, Baby G; Bygum, Anette

    2013-01-01

    and assayed for kallikrein formation. C1-INH was removed from factor XII-deficient plasma by means of immunoadsorption. RESULTS: We demonstrate that prekallikrein-HK will activate to kallikrein in phosphate-containing buffers and that the rate is further accelerated on addition of heat shock protein 90...... the prekallikrein-HK complex to prevent HK cleavage either by prekallikrein or by prekallikrein-HK autoactivation to generate kallikrein. In patients with hereditary angioedema, kallikrein and bradykinin formation can occur without invoking factor XII activation, although the kallikrein formed can rapidly activate...

  13. Retinal venous thrombosis in a young patient with coagulation factor XII deficiency.

    Science.gov (United States)

    Borrego-Sanz, L; Santos-Bueso, E; Sáenz-Francés, F; Martínez-de-la-Casa, J M; García-Feijoo, J; Gegúndez-Fernández, J A; García-Sánchez, J

    2014-08-01

    A 35-year-old woman, with no relevant medical history, was referred for sudden vision loss in the left eye. Ophthalmological examination showed best corrected visual acuity of 1.0 in the right eye and 0.3 in left eye, with normal anterior pole and intraocular pressure. Fundus examination of the left eye revealed a venous thrombosis in the superior temporal branch, with dilated and tortuous retinal veins. The patient was referred to the hematology unit for thrombophilia study, and was diagnosed with a coagulation XII or Hageman factor deficiency. The development of retinal vessel occlusions, in patients under 50 years of age, is frequently associated with thrombophilia or hypercoagulability disorders. Factor XII deficiency is a rare condition, and its presence could contribute to a higher risk of thromboembolic events. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  14. Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case

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    Di Micco Pierpaolo

    2005-12-01

    Full Text Available Abstract Background Antiphospholipid syndrome (APS has been often associated to RPL since 1980 and some reports in the Literature rarely described antibodies to factor XII in patients with APS. Case history We report the case history of 34-year-old caucasian women with recurrent fetal loss and persistent prolonged activated partial thromboplastin time. Haemostatic tests revealed persistent light decrease of clotting factor XII with normal values of IgG and IgM anticardiolipin antibodies and transient positivity for lupus anticoagulant (LA. Few reports in the Literature described antibodies to factor XII in patient with antiphospholipid syndrome (APS and transient LA. So, once other causes of RPL were excluded, the patient was diagnosed an unusual form of APS associated to antibodies to factor XII, reduced factor XII plasma levels, transient LA and prolonged activated partial thromboplastin time. Discussion We suggest to consider also antibodies directed to clotting factors (e.g. factor XII in our case as second step of thrombophilia screening in RPL, in particular if a persistent prolonged aPTT is present without an apparent cause.

  15. Immunoblotting studies of coagulation factor XII, plasma prekallikrein, and high molecular weight kininogen

    International Nuclear Information System (INIS)

    Laemmle, B.B.; Berrettini, M.; Griffin, J.H.

    1987-01-01

    Immunoblotting techniques for the qualitative and quantitative analysis of FXII, PK, and HMWK in whole plasma are presented. Sensitive, specific, and quantitative immunodetection of FXII and PK can be achieved by developing the blots with polyclonal antiserum followed by radiolabeled FXII or PK, respectively. This approach is based on the assumption that bivalent antibodies bind monovalently to the NC-bound antigen and have available binding sites to bind radiolabeled antigen derived from the fluid phase. This radiolabeled antigen overlay principle may be generally useful for immunodetection of any trace protein in complex mixtures, provided that the radiolabeled purified antigen is available. Immunoblotting may also be helpful for the partial characterization of the structural or functional abnormalities of CRM-positive variant molecules. For example, earlier studies of a FXII-variant molecule that had been purified and characterized were supported by immunoblotting studies of the CRM-positive deficient plasma. Quantitative measurement of HMWK is possible using a monoclonal antibody directed against the light chain of HMWK followed by radiolabeled secondary antibody. Quantitation of cleaved and single-chain HMWK is possible using dilutions of dextran sulfate-activated NHP on unreduced SDS-PAGE and dilutions of unactivated NHP with reduced SDS-PAGE as standards. These assays allow assessment of the degree of in vivo activation of the contact system in various disease states

  16. Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors

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    Gozzo A.J.

    2003-01-01

    Full Text Available Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be influenced by several factors including glycosaminoglycans, as recently demonstrated by our group. The aim of the present study was to investigate the effect of glycosaminoglycans (30 to 250 µg/ml on kallikrein activity on plasminogen and factor XII and on the inhibition of kallikrein by the plasma proteins C1-inhibitor and antithrombin. Almost all available glycosaminoglycans (heparin, heparan sulfate, bovine and tuna dermatan sulfate, chondroitin 4- and 6-sulfates reduced (1.2 to 3.0 times the catalytic efficiency of kallikrein (in a nanomolar range on the hydrolysis of plasminogen (0.3 to 1.8 µM and increased (1.9 to 7.7 times the enzyme efficiency in factor XII (0.1 to 10 µM activation. On the other hand, heparin, heparan sulfate, and bovine and tuna dermatan sulfate improved (1.2 to 3.4 times kallikrein inhibition by antithrombin (1.4 µM, while chondroitin 4- and 6-sulfates reduced it (1.3 times. Heparin and heparan sulfate increased (1.4 times the enzyme inhibition by the C1-inhibitor (150 nM.

  17. Trombosis cerebral en presencia de un inhibidor especifico contra el factor XII de la coagulación

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    Octavio Martínez Betancur

    1998-04-01

    Full Text Available We report the presence of an specific inhbitor directed against Hageman factor (factor XII in a male patient who suffered occlusive stroke and showed tomografic evidence of multiple previous brain infarcts. The presence of a lupus anticoagulant was excluded by means of the platelet neutralisation test. The reduction of the fibrinolytic activity in response to thrombosis as a result of factor XII inhibition was demonstrated by the abnormal prolongation of the euglobin lysis time as well as the absence of fibrin degradation products (negative D-dimer assay and ethanol gelation test.

  18. Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: Importance of sulfation pattern and molecular size.

    Science.gov (United States)

    Li, Junhui; Li, Shan; Yan, Lufeng; Ding, Tian; Linhardt, Robert J; Yu, Yanlei; Liu, Xinyue; Liu, Donghong; Ye, Xingqian; Chen, Shiguo

    2017-10-20

    Fucosylated chondroitin sulfates (fCSs) are structurally unusual glycosaminoglycans isolated from sea cucumbers that exhibit potent anticoagulant activity. These fCSs were isolated from sea cucumber, Isostichopus badionotus and Pearsonothuria graeffei. Fenton reaction followed by gel filtration chromatography afforded fCS oligosaccharides, with different sulfation patterns identified by mass and NMR spectroscopy, and these were used to clarify the relationship between the structures and the anticoagulant activities of fCSs. In vitro activities were measured by activated partial thromboplastin time (APTT), thrombin time (TT), thrombin and factor Xa inhibition, and activation of FXII. The results showed that free radicals preferentially acted on GlcA residues affording oligosaccharides that were purified from both fCSs. The inhibition of thrombin and factor X activities, mediated through antithrombin III and heparin cofactor II of fCSs oligosaccharides were affected by their molecular weight and fucose branches. Oligosaccharides with different sulfation patterns of the fucose branching had a similar ability to inhibit the FXa by the intrinsic factor Xase (factor IXa-VIIIa complex). Oligosaccharides with 2,4-O-sulfo fucose branches from fCS-Ib showed higher activities than ones with 3,4-O-disulfo branches obtained from fCS-Pg. Furthermore, a heptasaccharide is the minimum size oligosaccharide required for anticoagulation and FXII activation. This activity was absent for fCS oligosaccharides smaller than nonasaccharides. Molecular size and fucose branch sulfation are important for anticoagulant activity and reduction of size can reverse the activation of FXII caused by native fCSs. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. Factor XII (Hageman factor) is a missing link between stress and hypercoagulability and plays an important role in the pathophysiology of ischemic stroke.

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    Eggers, Arnold E

    2006-01-01

    A new hypothesis is presented on the function of factor XII, which is postulated to be a "missing link" between acute stress and transient hypercoagulability. The implications of this idea are developed to show how chronic stress, which involves activation of hypertension and migraine as well as hypercoagulability, can cause of cerebrovascular disease. "Acute stress" is defined as "the normal short-term physiological response to the perception of major threats or demands". "Chronic stress" is "the abnormal ongoing physiological response to the continuing perception of unresolvable major threats or demands". The factor XII hypothesis is as follows: Acute stress includes release of epinephrine by the adrenal medulla. Epinephrine activates platelets by binding to alpha-2A adrenergic receptors. Activated platelets convert pre-bound factor XII to its active form, which then initiates the intrinsic coagulation cascade. This can be called the "activated platelet initiation pathway" for coagulation. Neither tissue factor nor pre-formed thrombin is required. Thrombosis proceeds to completion, but only a minute amount of thrombin is formed, and the process normally stops at this point. In people who lapse into a state of chronic stress, essential hypertension, which is also a manifestation of stress, synergizes with hypercoagulability: there is both a baseline rise in blood pressure and systemic platelet activation as well as superimposed labile rises of both. Upregulation of these two stress parameters is atherogenic: epinephrine-activated platelets stimulating thrombin formation interact with endothelial cells activated by angiotensin II to cause, first, smooth muscle cell proliferation, which is a histological hallmark of atherosclerosis, and, lastly, a symptomatic thrombotic occlusion-the stroke. The migraine symptoms which often accompany this process are a marker of chronic stress and ongoing pathophysiologic damage. Therapeutic predictions are made regarding novel

  20. Factor XII assay

    Science.gov (United States)

    ... your provider about the meaning of your specific test results. What Abnormal Results ... vary in size so it may be harder to take a blood sample from one person than another. Other slight risks from having ...

  1. Crew Factors in Flight Operations XII: A Survey of Sleep Quantity and Quality in On-Board Crew Rest Facilities

    Science.gov (United States)

    Rosekind, Mark R.; Gregory, Kevin B.; Co, Elizabeth L.; Miller, Donna L.; Dinges, David F.

    2000-01-01

    Many aircraft operated on long-haul commercial airline flights are equipped with on-board crew rest facilities, or bunks, to allow crewmembers to rest during the flight. The primary objectives of this study were to gather data on how the bunks were used, the quantity and quality of sleep obtained by flight crewmembers in the facilities, and the factors that affected their sleep. A retrospective survey comprising 54 questions of varied format addressed demographics, home sleep habits, and bunk sleep habits. Crewmembers from three airlines with long-haul fleets carrying augmented crews consisting of B747-100/200, B747-400, and MD-11 aircraft equipped with bunks returned a total of 1404 completed surveys (a 37% response rate). Crewmembers from the three carriers were comparable demographically, although one carrier had older, more experienced flight crewmembers. Each group, on average, rated themselves as "good" or "very good" sleepers at home, and all groups obtained about the same average amount of sleep each night. Most were able to sleep in the bunks, and about two thirds indicated that these rest opportunities benefited their subsequent flight deck alertness and performance. Comfort, environment, and physiology (e.g., being ready for sleep) were identified as factors that most promoted sleep. Factors cited as interfering with sleep included random noise, thoughts, heat, and the need to use the bathroom. These factors, in turn, suggest potential improvements to bunk facilities and their use. Ratings of the three aircraft types suggested differences among facilities. Bunks in the MD-11 were rated significantly better than either of the B747 types, and the B747-400 bunks received better ratings than did the older, B747-100/200 facilities.

  2. Novel Mechanism of Plasma Prekallikrein (PK) Activation by Vascular Smooth Muscle Cells: Evidence of the presence of PK Activator

    OpenAIRE

    Keum, Joo-Seob; Jaffa, Miran A; Luttrell, Louis M; Jaffa, Ayad A.

    2014-01-01

    The contribution of plasma prekallikrein (PK) to vascular remodeling is becoming increasingly recognized. Plasma PK is activated when the zymogen PK is digested to an active enzyme by activated factor XII (FXII). Here, we present our findings that vascular smooth muscle cells (VSMC) activate plasma PK in the absence of FXII. Extracted plasma membrane and cytosolic fractions of VSMCs activate PK, but the rate of PK activation was greater by the membrane fraction. FXII neutralizing antibody did...

  3. Special issue: Proceedings of the XII. Czech Ichthyological Conference

    Czech Academy of Sciences Publication Activity Database

    Kubečka, Jan

    2011-01-01

    Roč. 60, č. 2 (2011), s. 91-92 ISSN 0139-7893. [Czech Ichthyological Conference /XII./. Vodňany, 19.05.2010-20.05.2010] Institutional research plan: CEZ:AV0Z60170517 Keywords : zoology * ichthyology Subject RIV: EG - Zoology Impact factor: 0.554, year: 2011

  4. Collagen XII myopathy with rectus femoris atrophy and collagen XII retention in fibroblasts

    DEFF Research Database (Denmark)

    Witting, Nanna; Krag, Thomas; Werlauff, Ulla

    2018-01-01

    INTRODUCTION: Mutation in the collagen XII gene (COL12A1) was recently reported to induce Bethlem myopathy. We describe a family affected by collagen XII-related myopathy in 3 generations. METHODS: Systematic interview, clinical examination, skin biopsies, and MRI of muscle were used. RESULTS...... affection and abnormal collagen XII retention in fibroblasts. MRI disclosed a selective wasting of the rectus femoris muscle. DISCUSSION: COL12A1 mutations should be considered in patients with a mild Bethlem phenotype who present with selective wasting of the rectus femoris, absence of the outside......-in phenomenon on MRI, and abnormal collagen XII retention in fibroblasts. Muscle Nerve, 2018....

  5. Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis

    NARCIS (Netherlands)

    Franco, R. F.; Reitsma, P. H.; Lourenço, D.; Maffei, F. H.; Morelli, V.; Tavella, M. H.; Araújo, A. G.; Piccinato, C. E.; Zago, M. A.

    1999-01-01

    A mutation in the factor XIII gene (FXIII Val34Leu) gene was recently reported to confer protection against myocardial infarction, but its relationship with venous thrombosis is unknown. In addition, a mutation in the 5'-untranslated region of the FXII gene (46 C->T) was identified which is

  6. XII seminar on problems of reactor physics

    International Nuclear Information System (INIS)

    Kryuchkov, Eh.F.; Naumov, V.I.

    2003-01-01

    Results of the XII seminar Physical problems of effective and safety use of nuclear materials taking place on the basis of MEPI (September, 2002) are discussed. Reports on the directions: physical problems of advanced nuclear-energetic technologies; account, control and nuclear material management; effective and safety use of nuclear materials at NPP; programming and software for the analysis of physical processes are performed. Of particular interest is reports on actual problems of nuclear energetics and fuel cycle, on ill-intentioned use of fissile materials, efficiency of long-lived isotopes transmutation and spent fuel management [ru

  7. Pius XII and the Jews: A Bibliographical Review.

    Science.gov (United States)

    Byers, Catherine

    1978-01-01

    Presents a brief biographical sketch of Pope Pius XII and samples literary treatment of Pius's actions with respect to Nazi atrocities against the Jewish people during World War II. Concludes that Pope Pius XII failed to show moral leadership. Materials reviewed include historical texts, studies of the Vatican, documents related to the war period,…

  8. La host (1998) Any XII. Núm. 7

    OpenAIRE

    Alè Revest, Josep Lluis; Agustí i Vicent, Joan; Belenguer, Emília; Sánchez-Pantoja Domínguez, Albert; Francisco, José Vicente; Trilles Font, Joan Josep; Gómez, Vicent; García Moliner, Federico; García, Agustín; Vicente, Ricardo; Alcón, Jaume; Gimeno, Vicent; Pallarés, Joan; Fernandez Jurado, Ramón; Lauterio, Amàlia

    1998-01-01

    SUMARI: Salutació.Crònica reial.La host.La torre dels Alçaments (i II).Casa i Cort dels reis d'Aragó (II).El bou en la cultura mediterrània.Joan Fuster,"in memoriam".Les illes columbretes.Bernat de Ventadorn, trobador d'ofici.Sant Antoni: Animals, dimonis i foc.III Capitol de l'arros i la taronja.Decàleg de promeses solemnes.Decàleg de promeses solemnes.Guijuelo:23-II-97 I capitol del jamón (XII jornadas de la matanza).Hernani: 23-III-97 II capítol de la sidra.Santander: 20-IV-97 XIII Capítol...

  9. Formation of ice XII at low temperatures and high pressures

    International Nuclear Information System (INIS)

    Schober, H.; Koza, M.; Toelle, A.; Fujara, F.

    1999-01-01

    Complete text of publication follows. Solid water features a large variety of crystalline as well as two amorphous phases. The versatility of water's behavior has been reinforced recently by the identification of still another form of crystalline ice [1]. Ice XII was obtained by cooling liquid water to 260 K at a pressure of 5.5 kbar. Ice XII could be produced in a completely different region of water's phase diagram [2]. Using a. piston-cylinder apparatus ice XII was formed during the production of high-density amorphous ice (HDA) at 77 K as described previously [3]. The amount of crystalline ice XII contamination within the HDA sample varies in a so far unpredictable way with both extremes, i.e. pure HDA as well as pure ice XII. realized. Our results indicate that water's phase diagram needs modification in the region assigned to HDA. Ice XII is characterized as well as its transition towards cubic ice by elastic and inelastic neutron scattering. (author)

  10. 1. XII kell 13 avatakse Pärnu uue kunsti muuseumis...

    Index Scriptorium Estoniae

    2002-01-01

    Jõulunäitus "Kunst kuulub lastele!" kunstnike ja laste töödest. 6.-8. XII tekstiilipäevad (Anu Raud, Hilja Kulles); 13.-15. XII piparkoogipäevad; 20.-21. XII inglipäevad (kutsutud Ilon Wikland); 27-29. XII unenäopäevad (Enn Tegova). Saab vaadata Lasse Naukarise filmi "Kunstniku elu"

  11. Comparision of analysis of the QTLMAS XII common dataset

    DEFF Research Database (Denmark)

    Crooks, Lucy; Sahana, Goutam; de Koning, Dirk-Jan

    2009-01-01

    As part of the QTLMAS XII workshop, a simulated dataset was distributed and participants were invited to submit analyses of the data based on genome-wide association, fine mapping and genomic selection. We have evaluated the findings from the groups that reported fine mapping and genome-wide asso...

  12. Alates 13. XII on Vaala galeriis avatud "Talvesalong"

    Index Scriptorium Estoniae

    2004-01-01

    Väljas on Ellinor Aiki, Valdur Ohaka, Herman Talviku, Jaak Arro, Raoul Kurvitza, Andres Toltsi, Laurentsiuse, Lembit Saartsi, Rait Rosina, Merike Estna, Maarit Murka ning Aleksandr Breneri ja Barbara Schurzi tööd. 17. XII Anna Litvinova, Ilmar Kruusamäe ja Lembit Sarapuu ühised maaliseansid

  13. Comparision of analysis of the QTLMAS XII common dataset

    DEFF Research Database (Denmark)

    Lund, Mogens Sandø; Sahana, Goutam; de Koning, Dirk-Jan

    2009-01-01

    A dataset was simulated and distributed to participants of the QTLMAS XII workshop who were invited to develop genomic selection models. Each contributing group was asked to describe the model development and validation as well as to submit genomic predictions for three generations of individuals...

  14. Platonismo e Aristotelismo no século XII (I

    Directory of Open Access Journals (Sweden)

    Ruy Afonso da Costa Nunes

    1968-09-01

    Full Text Available Consagro esta monografia ao estudo de "Platonismo e Aristote-lismo no século XII". Sua concisão talvez não corresponda ao vulto das leituras e consultas a que o tema me compeliu. Confesso, entre-tanto, que ela corresponde aos intuitos com que a concebi, após ter recebido a incumbência de redigí-Ia durante o curso de doutoramen-to, para a cadeira de Língua e Literatura Latina .

  15. Jalutuskäik Tallinna galeriides laupäeval, 17. XII / Juta Kivimäe

    Index Scriptorium Estoniae

    Kivimäe, Juta, 1952-

    2005-01-01

    Jaan Elkeni ja Anu Põdra ühisnäitus "Mina ja tema" Deco galeriis kuni 30. XII. Kristin Kalamehe näitus "Mehed" Tallinna Linnagaleriis kuni 1. I 2006. Alice Kase joonistused Hobusepea galeriis 13.-19. XII. Rita Raave näitus "Vana sein" G-galeriis kuni 31. XII

  16. Type XII and XIV collagens mediate interactions between banded collagen fibers in vitro and may modulate extracellular matrix deformability.

    Science.gov (United States)

    Nishiyama, T; McDonough, A M; Bruns, R R; Burgeson, R E

    1994-11-11

    Type XII and XIV collagens are very large molecules containing three extended globular domains derived from the amino terminus of each alpha chain and an interrupted triple helix. Both collagens are genetically and immunologically unique and have distinct distributions in many tissues. These collagens localize near the surface of banded collagen fibrils. The function of the molecules is unknown. We have prepared a mixture of native type XII and XIV collagens that is free of contaminating proteins by electrophoretic criteria. In addition, we have purified the collagenase-resistant globular domains of type XII or XIV collagens (XII-NC-3 or XIV-NC-3). In this study, we have investigated the effect of intact type XII and XIV and XII-NC-3 or XIV-NC-3 on the interactions between fibroblasts and type I collagen fibrils. We find that both type XII and XIV collagens promote collagen gel contraction mediated by fibroblasts, even in the absence of serum. The activity is present in the NC-3 domains. The effect is dose-dependent and is inhibited by denaturation. The effect of type XII NC-3 is inhibited by the addition of anti-XII antiserum. To elucidate the mechanism underlying this phenomenon, we examined the effect of XII-NC-3 or XIV-NC-3 on deformability of collagen gels by centrifugal force. XII-NC-3 or XIV-NC-3 markedly promotes gel compression after centrifugation. The effect is also inhibited by denaturation, and the activity of type XII-NC3 is inhibited by the addition of anti-XII antiserum. The results indicate that the effect of XII-NC-3 or XIV-NC-3 on collagen gel contraction by fibroblasts is not due to activation of cellular events but rather results from the increase in mobility of hydrated collagen fibrils within the gel. These studies suggest that collagen types XII and XIV may modulate the biomechanical properties of tissues.

  17. 40 CFR Appendix Xii to Part 266 - Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery Furnaces XII Appendix XII to Part 266... FACILITIES Pt. 266, App. XII Appendix XII to Part 266—Nickel or Chromium-Bearing Materials that may be...

  18. XII International Conference of the Italian Association on Artificial Intelligence

    CERN Document Server

    Semeraro, Giovanni; Vargiu, Eloisa; New Challenges in Distributed Information Filtering and Retrieval : DART 2011: Revised and Invited Papers

    2013-01-01

    This volume focuses on new challenges in distributed Information Filtering and Retrieval. It collects invited chapters and extended research contributions from the DART 2011 Workshop, held in Palermo (Italy), on September 2011, and co-located with the XII International Conference of the Italian Association on Artificial Intelligence. The main focus of DART was to discuss and compare suitable novel solutions based on intelligent techniques and applied to real-world applications. The chapters of this book present a comprehensive review of related works and state of the art. Authors, both practitioners and researchers, shared their results in several topics such as "Multi-Agent Systems", "Natural Language Processing", "Automatic Advertisement", "Customer Interaction Analytics", "Opinion Mining".

  19. XII International Conference on the Theory of Machines and Mechanisms

    CERN Document Server

    Bílek, Martin; Žabka, Petr

    2017-01-01

    This book presents the most recent advances in the research of machines and mechanisms. It collects 54 reviewed papers presented at the XII International Conference on the Theory of Machines and mechanisms (TMM 2016) held in Liberec, Czech Republic, September 6-8, 2016. This volume offers an international selection of the most important new results and developments, grouped in six different parts, representing a well-balanced overview, and spanning the general theory of machines and mechanisms, through analysis and synthesis of planar and spatial mechanisms, linkages and cams, robots and manipulators, dynamics of machines and mechanisms, rotor dynamics, computational mechanics, vibration and noise in machines, optimization of mechanisms and machines, mechanisms of textile machines, mechatronics to the control and monitoring systems of machines. This conference is traditionally organised every four year under the auspices of the international organisation IFToMM and the Czech Society for Mechanics.

  20. Molecular Cloning and Characterization of Carbonic Anhydrase XII from Pufferfish (Takifugu rubripes

    Directory of Open Access Journals (Sweden)

    Kanij Rukshana Sumi

    2018-03-01

    Full Text Available In this study, an 1888-bp carbonic anhydrase XII (CA XII sequence was cloned from the brain of the pufferfish, Takifugu rubripes. The cloned sequence contained a coding region of 1470-bp, which was predicted to translate into a protein of 490 amino acid residues. The predicted protein showed between 68–56% identity with the large yellow croaker (Larimichthys crocea, tilapia (Oreochromis niloticus, and Asian arowana (Scleropages formosus CA XII proteins. It also exhibited 36% and 53% identity with human CA II and CA XII, respectively. The cloned sequence contained a 22 amino acid NH2-terminal signal sequence and three Asn-Xaa-Ser/Thr sequons, among which one was potentially glycosylated. Four cysteine residues were also identified (Cys-21, Cys-201, Cys-355, and Cys-358, two of which (Cys-21 and Cys-201 could potentially form a disulfide bond. A 22-amino acid COOH-terminal cytoplasmic tail containing a potential site for phosphorylation by protein kinase A was also found. The cloned sequence might be a transmembrane protein, as predicted from in silico and phylogenetic analyses. The active site analysis of the predicted protein showed that its active site residues were highly conserved with tilapia CA XII protein. Homology modeling of the pufferfish CA XII was done using the crystal structure of the extracellular domain of human carbonic anhydrase XII at 1.55 Å resolution as a template. Semi-quantitative reverse transcription (RT-PCR, quantitative PCR (q-PCR, and in situ hybridization confirmed that pufferfish CA XII is highly expressed in the brain.

  1. Contact activation of blood-plasma coagulation

    Science.gov (United States)

    Golas, Avantika

    Surface engineering of biomaterials with improved hemocompatibility is an imperative, given the widespread global need for cardiovascular devices. Research summarized in this dissertation focuses on contact activation of FXII in buffer and blood plasma frequently referred to as autoactivation. The extant theory of contact activation imparts FXII autoactivation ability to negatively charged, hydrophilic surfaces. According to this theory, contact activation of plasma involves assembly of proteins comprising an "activation complex" on activating surfaces mediated by specific chemical interactions between complex proteins and the surface. This work has made key discoveries that significantly improve our core understanding of contact activation and unravel the existing paradigm of plasma coagulation. It is shown herein that contact activation of blood factor XII (FXII, Hageman factor) in neat-buffer solution exhibits a parabolic profile when scaled as a function of silanized-glass-particle activator surface energy (measured as advancing water adhesion tension t°a=g° Iv costheta in dyne/cm, where g°Iv is water interfacial tension in dyne/cm and theta is the advancing contact angle). Nearly equal activation is observed at the extremes of activator water-wetting properties --36 moderated by adsorption of plasma proteins unrelated to coagulation through an "adsorption-dilution" effect that blocks FXII contact with hydrophobic activator surfaces. The adsorption-dilution effect explains the apparent specificity for hydrophilic activators pursued by earlier investigators. Finally a comparison of FXII autoactivation in buffer, serum, protein cocktail, and plasma solutions is shown herein. Activation of blood plasma coagulation in vitro by contact with material surfaces is demonstrably dependent on plasma-volume-to-activator-surface-area ratio. However, activation of factor XII dissolved in buffer, protein cocktail, heat-denatured serum, and FXI deficient plasma does not

  2. The lower cranial nerves: IX, X, XI, XII.

    Science.gov (United States)

    Sarrazin, J-L; Toulgoat, F; Benoudiba, F

    2013-10-01

    The lower cranial nerves innervate the pharynx and larynx by the glossopharyngeal (CN IX) and vagus (CN X) (mixed) nerves, and provide motor innervation of the muscles of the neck by the accessory nerve (CN XI) and the tongue by the hypoglossal nerve (CN XII). The symptomatology provoked by an anomaly is often discrete and rarely in the forefront. As with all cranial nerves, the context and clinical examinations, in case of suspicion of impairment of the lower cranial nerves, are determinant in guiding the imaging. In fact, the impairment may be located in the brain stem, in the peribulbar cisterns, in the foramens or even in the deep spaces of the face. The clinical localization of the probable seat of the lesion helps in choosing the adapted protocol in MRI and eventually completes it with a CT-scan. In the bulb, the intra-axial pathology is dominated by brain ischemia (in particular, with Wallenberg syndrome) and multiple sclerosis. Cisternal pathology is tumoral with two tumors, schwannoma and meningioma. The occurrence is much lower than in the cochleovestibular nerves as well as the leptomeningeal nerves (infectious, inflammatory or tumoral). Finally, foramen pathology is tumoral with, outside of the usual schwannomas and meningiomas, paragangliomas. For radiologists, fairly hesitant to explore these lower cranial pairs, it is necessary to be familiar with (or relearn) the anatomy, master the exploratory technique and be aware of the diagnostic possibilities. Copyright © 2013 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  3. High density amorphous ice and its phase transition to ice XII

    International Nuclear Information System (INIS)

    Kohl, I.

    2001-07-01

    1998 Lobban et al. reported the neutron diffraction data of a new phase of ice, called ice XII, which formed at 260 K on compression of water within the domain of ice V at a pressure of 0.5 GPa. Surprisingly ice XII forms as an incidental product in the preparation of high-density amorphous ice (HDA) on compression of hexagonale ice (ice Ih) at 77 K up to pressures = 1.3 GPa. A decisive experimental detail is the use of an indium container: when compressing ice Ih in a pressure vessel with indium linings, then reproducibly HDA (high density amorphous ice) forms, but without indium randomly scattered relative amounts of ice XII and HDA form. Ice XII forms on compression of ice Ih at 77 K only via HDA, and not directly from ice Ih. Its formation requires a sudden pronounced apparent pressure drop of ca 0.18 GPa at pressures ca 1.1 GPa. These apparent pressure drops can be caused by buildup friction between the piston and the pressure vessel and its sudden release on further compression. I propose that shock-waves generated by apparent pressure drops cause transient local heating and that this induces nucleation and crystal growth. A specific reproducible method to prepare ice XII is heating HDA in a pressure vessel with indium linings at constant pressures (or constant volume). The ice XII (meta-)stability domain extends between ca 158 and 212 K from ca 0.7 to ca 1.5 GPa. DSC (differential scanning calorimetry) and x-ray powder diffraction revealed, that on heating at atmospheric pressure ice XII transforms directly into cubic ice (ice Ic) at 154 K (heating rate 10 K min - 1) and not into an amorphous form before transition to ice Ic. The enthalpy of the ice XII - ice Ic transition is -1.21 ± 0.07 kJ mol -1 . An estimation of the Gibbs free energy at atmospheric pressure and about 140 K results that ice XII is thermodynamically more stable than ice VI. In the heating curve of ice XII a reversible endothermic step can be found at the onset temperature (heating rate

  4. 40 CFR Appendix Xii to Part 86 - Tables for Production Compliance Auditing of Heavy-Duty Engines and Heavy-Duty Vehicles...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Tables for Production Compliance Auditing of Heavy-Duty Engines and Heavy-Duty Vehicles, Including Light-Duty Trucks XII Appendix XII to... Appendix XII to Part 86—Tables for Production Compliance Auditing of Heavy-Duty Engines and Heavy-Duty...

  5. The Mast Cell, Contact, and Coagulation System Connection in Anaphylaxis

    Directory of Open Access Journals (Sweden)

    Mar Guilarte

    2017-07-01

    Full Text Available Anaphylaxis is the most severe form of allergic reaction, resulting from the effect of mediators and chemotactic substances released by activated cells. Mast cells and basophils are considered key players in IgE-mediated human anaphylaxis. Beyond IgE-mediated activation of mast cells/basophils, further mechanisms are involved in the occurrence of anaphylaxis. New insights into the potential relevance of pathways other than mast cell and basophil degranulation have been unraveled, such as the activation of the contact and the coagulation systems. Mast cell heparin released upon activation provides negatively charged surfaces for factor XII (FXII binding and auto-activation. Activated FXII, the initiating serine protease in both the contact and the intrinsic coagulation system, activates factor XI and prekallikrein, respectively. FXII-mediated bradykinin (BK formation has been proven in the human plasma of anaphylactic patients as well as in experimental models of anaphylaxis. Moreover, the severity of anaphylaxis is correlated with the increase in plasma heparin, BK formation and the intensity of contact system activation. FXII also activates plasminogen in the fibrinolysis system. Mast cell tryptase has been shown to participate in fibrinolysis through plasmin activation and by facilitating the degradation of fibrinogen. Some usual clinical manifestations in anaphylaxis, such as angioedema or hypotension, or other less common, such as metrorrhagia, may be explained by the direct effect of the activation of the coagulation and contact system driven by mast cell mediators.

  6. Transmembrane carbonic anhydrase isozymes IX and XII in the female mouse reproductive organs

    Directory of Open Access Journals (Sweden)

    Tomas Eija

    2004-10-01

    Full Text Available Abstract Background Carbonic anhydrase (CA classically catalyses the reversible hydration of dissolved CO2 to form bicarbonate ions and protons. The twelve active CA isozymes are thought to regulate a variety of cellular functions including several processes in the reproductive systems. Methods The present study was designed to investigate the expression of transmembrane CAs, CA IX and XII, in the mouse uterus, ovary and placenta. The expression of CA IX and XII was examined by immunoperoxidase staining method and western blotting. CA II and XIII served as positive controls since they are known to be present in the mouse reproductive tract. Results The data of our study indicated that CA XII is expressed in the mouse endometrium. Only very faint signal was observed in the corpus luteum of the ovary and the placenta remained mainly negative. CA IX showed weak reaction in the endometrial epithelium, while it was completely absent in the ovary and placenta. Conclusion The conservation of CA XII expression in both mouse and human endometrium suggests a role for this isozyme in reproductive physiology.

  7. Stroke prevention--a population screening day in district XII of Budapest.

    Science.gov (United States)

    Folyovich, András; Bakos, Mária; Kántor, Zita; Hertelendy, Anna; Horváth, Eszter; Zsiga, Katalin; Lakatos, Henriette; Vadasdi, Károly

    2012-03-30

    Along with advances in the treatment of acute stroke, new efforts have been made to enhance efficiency of the prevention of cerebrovascular diseases. Population screening is a way to contact high-risk patients, and there is an increasing international and national experience with the procedure. However, efforts are associated with high costs, so an efficient method, complying with local features, should be selected from the various methods. A stroke prevention day was organized in Szent János Hospital, localized in district XII, and data were analyzed. Taking advantage of the potentials of a large hospital, a comprehensive risk assessment - within the capacity of health care workers - was performed. Program and contact information of the screening day was published in the local newspaper of the district. Data of 48 residents of the district were analyzed. In addition to neurologists, a radiologist, a cardiologist and an ophtalmologist, as well as health care workers were involved in the project. A data sheet was filled in for all participants, including known risk factors, BMI, blood pressure and serum cholesterol levels. All participants had duplex sonography of the cervical vessels, cardiac evaluation and ophtalmic examination. Data were analyzed anonymously, and - if participants approved - postcode and educational level were also recorded. Among the 48 individuals screened, 35 were female and 13 were male. Average age was 62.86 (+/- 8.57) years, and participants were typically of higher educational level. 5 individuals had no known risk factors, most of them had 2-3 risk factors, and multiple risk factors were not uncommon. Individuals with six and seven risk factors were also found. 20 of 27 patients with known hypertension had target blood pressure levels. By duplex sonography, 36 individuals had mild, 4 had significant atherosclerosis. There was no significant carotid stenosis or occlusion. Based on ophtalmic evaluation, 26 patients had signs of vascular

  8. FAKTOR-FAKTOR YANG MEMPENGARUHI KREATIVITAS BELAJAR SISWA KELAS XII PEMASARAN PADA PEMBELAJARAN PRODUKTIF PEMASARAN DI SMK NEGERI 1 PURBALINGGA

    Directory of Open Access Journals (Sweden)

    Widiyaningrum Widiyaningrum

    2016-11-01

    Full Text Available Kurikulum 2013 merupakan kurikulum yang bertujuan untuk meningkatkan keaktifan, kreativitas, inovasi dan produktivitas.SMK N 1 Purbalingga merupakan SMK yang sudah menerapkan Kurikulum 2013, akan tetapi kreativitas siswa kelas XII Pemasaran masih rendah. Siswa masih memiliki kreativitas yang rendah pada materi penataan produk dan promosi produk. Kreativitas dapat dipengaruhi oleh faktor-faktor yang mempengaruhi. Faktor yang mempengaruh kreativitas yaitu situasi yang mengadirkan ketidaklengkapan serta keterbukaan, situasi yang memungkinkan dan mendorong banyak pertanyaan, situasi yang mendorong dalam rangka menghasilkan sesuatu, situasi yang mendorong tanggung jawab dan kemandirian, situasi yang menekankan inisiatif diri, kedwibahasaan. perhatian dari orang tuastimulasi dari lingkungan sekolah, motivasi diri. Penelitian ini menggunakan pendekatan kuantitatif dengan jumlah responden 38 siswa. metode pengumpulan datamenggunakan angket, dan metode analisis data menggunakan analisis faktor untuk mengetahui faktor dominan yang mempengaruhi kreativitas. Hasil penelitian menunjukkan terdapat dua faktor dominan yang mempengaruhi kreativitas, yaitu keadaan saat pembelajaran dan rangsangan dari lingkungan. Sehingga dapat disimpulkan bahwa kreativitas belajar siswa dipengaruhi oleh keadaan saat pembelajaran dan rangsangan dari lingkungan. Curriculum 2013 is a curriculum that aims to enhance the activity, creativity, innovation and productivity. SMK N 1 Purbalingga is already implementing vocational curriculum in 2013, but the creativity of students of class XII Marketing is still low. Students still have the creativity that is low on product structuring materials and promotional products. Creativity can be affected by factors affecting. Factors that influence the creativity that is the situation that presents the incompleteness and openness, a situation that enables and encourages a lot of questions, the situation is encouraging in order to produce

  9. Multiplier Effect Industri Pariwisata Candi Muara Takus Terhadap Perekonomian Masyarakat Di Kecamatan XII Koto Kampar Kabupaten Kampar

    OpenAIRE

    Ikhsan, Muhammad; ', Mardiana; Setiawan, Deny

    2017-01-01

    The research was carried on in Kampar regency precisely in the District XII Koto Kampar. This study was conducted in Kampar regency located in District XII Koto Kampar. This study aims to (1) Identify the characteristics of visitors, businessmen and labor (2) To identify the perception of the condition of Tourism Muara Takus by visitors, businesses and workers in the tourist area (3) Measuring multiplier effet that caused by Muara Takus tourist activities on the economy of the community. The ...

  10. Ludus de Antichristo e o drama da escatologia imperial no século XII

    Directory of Open Access Journals (Sweden)

    Vinicius Cesar Dreger de Araújo

    2013-09-01

    Full Text Available Buscamos neste texto analisar as imbricações entre o texto teatral germânico do século XII, o Ludus de Antichristo, e o seu contexto político-cultural, particularmente em relação às personagens do Anticristo e do Último Imperador Romano, seus protagonistas, com a Escatologia Imperial encontrada no período. Nosso artigo contém um detalhado resumo da peça, estudos relacionados às tradições e documentos que levaram à sua concepção e seu enquadramento nos debates políticos e religiosos do século XII.

  11. XII All-Russian conference on gas chromatography. Program. Summary of reports

    International Nuclear Information System (INIS)

    2002-01-01

    Program and summary of reports of the XII All-Russian conference on gas chromatography are performed. The conference took place in Samara, 10-14 June, 2002. Reports on physicochemical regularities of gas chromatography, application of chromatographic methods in atomic energetics are included in the program of the conference. Part of the reports are deleted to the analytical application of the gas chromatography. Adsorbents for the gas chromatography, complex methods, mathematic methods in chromatography, ecological aspects of the gas chromatography [ru

  12. NPP safety and personnel training. XII International conference. Abstracts. Volume 2

    International Nuclear Information System (INIS)

    2011-01-01

    The XII International conference NPP Safety and Personnel Training took place in Obninsk, October 4-7 2011. The problems of personnel training for nuclear industry are discussed. The innovation nuclear systems and fuel cycle are considered. The much attention has been given to NPP radiation safety and radioecology issues. The recent high-speed computation and simulation methods used in reactor technology are presented [ru

  13. Forces necessary for the disruption of the cisternal segments of cranial nerves II through XII.

    Science.gov (United States)

    Tubbs, R Shane; Wellons, John C; Blount, Jeffrey P; Salter, E George; Oakes, W Jerry

    2007-04-01

    Manipulation of the cisternal segment of cranial nerves is often performed by the neurosurgeon. To date, attempts at quantifying the forces necessary to disrupt these nerves in situ, to our knowledge, has not been performed. The present study seeks to further elucidate the forces necessary to disrupt the cranial nerves while within the subarachnoid space. The cisternal segments of cranial nerves II through XII were exposed in six unfixed cadavers, all less than 6 hr postmortem. Forces to failure were then measured. Mean forces necessary to disrupt nerves for left sides in increasing order were found for cranial nerves IX, VII, IV, X, XII, III, VIII, XI, VI, V, and II, respectively. Mean forces for right-sided cranial nerves in increasing order were found for cranial nerves IX, VII, IV, X, XII, VIII, V, VI, XI, III, and II, respectively. Overall, cranial nerves requiring the least amount of force prior to failure included cranial nerves IV, VII, and IX. Those requiring the highest amount of force included cranial nerves II, V, VI, and XI. There was an approximately ten-fold difference between the least and greatest forces required to failure. Cranial nerve III was found to require significantly (P cranial nerves II through XII. We found that cranial nerve IX consistently took the least amount of force until its failure and cranial nerve II took the greatest. Other cranial nerves that took relatively small amount of force prior to failure included cranial nerves IV and VII. Although in vivo damage can occur prior to failure of a cranial nerve, our data may serve to provide a rough estimation for the maximal amount of tension that can be applied to a cranial nerve that is manipulated while within its cistern.

  14. Use of Al XII and Mg XI lines as solar plasma diagnostics

    International Nuclear Information System (INIS)

    Bromage, B.J.I.; Phillips, K.J.H.; Keenan, F.P.; McCann, S.M.

    1989-09-01

    We present three sets of observations of n=1 to n=2 lines due to helium-like aluminium (Al XII), made during two solar flares (25 August, 1980 and 19 October, 1986), using the X-ray Polychromator on satellite. The observed temperature-sensitive line ratio G is shown to be consistent with previously observed close-coupling calculations, although the ratio R, which is both temperature and density-sensitive for lower-Z elements, is not sufficiently well determined from these data to say more than that the observed values of R are not inconsistent with the theoretical calculations. This region of the spectrum also includes the helium-like magnesium (Mg XI) 1 1 S-3 1 P line, and it is shown that the ratio of this line to the Al XII resonance (1 1 S-2 1 P) line is a more sensitive indicator of electron temperature than are the Al XII G and R ratios. We demonstrate that the three ratios may be used together in order to derive values of emission measure, electron temperature and electron density during these flares. (author)

  15. Analyses of the Sn IX-Sn XII spectra in the EUV region

    International Nuclear Information System (INIS)

    Churilov, S S; Ryabtsev, A N

    2006-01-01

    The Sn IX-Sn XII spectra excited in a vacuum spark have been analysed in the 130-160 A wavelength region. The analysis was based on the energy parameter extrapolation in the isonuclear Sn VI-VIII and Sn XIII-XIV sequence. 266 spectral lines belonging to the 4d m -(4d m-1 4f+4p 5 4d m+1 ) (m=6-3) transition arrays were classified in the Sn IX-Sn XII spectra for the first time. All 18 level energies of the 4d 3 configuration and 39 level energies of the strongly interacting 4d 2 4f and 4p 5 4d 4 configurations were established in the Sn XII spectrum. The energy differences between the majority of the 4d m levels and about 40 levels of the 4d m-1 4f+4p 5 4d m+1 configurations were determined in each of the Sn IX, Sn X and Sn XI spectra (m=6-4). As a result, all intense lines were classified in the 130-140 A region relevant to the extreme ultraviolet (EUV) lithography. It was shown that the most of the intense lines in the 2% bandwidth at 135 A belong to the transitions in the Sn XI-Sn XIII spectra

  16. 2. XII möödus 20 aastat Adamson-Ericu muuseumi avamisest Eesti Kunstimuuseumi filiaalina ning 35 aastat Adamson-Ericu (1902-1968) surmast

    Index Scriptorium Estoniae

    2003-01-01

    Muuseumi ajaloost, põhikogust, Adamson-Ericu teoste põhiekspositsioonist, kunstinäitustest. 3. XII tutvustab Kersti Koll Adamson-Ericu ja läti kunstniku Ludolfs Libertsi näitust. 5. XII ekspositsioonis ringkäik "Meistri töövõtetest ning erinevatest materjalidest restauraatori pilgu läbi" Alar Nurkse juhtimisel, ekskursioon Ülle Kruusi juhtimisel. 10. XII algab projekti "Avatud muuseum" raames haridusprogramm "Noor kunstidetektiiv"

  17. XII Encuentro Científico “Desarrollo, innovación y salud”

    Directory of Open Access Journals (Sweden)

    Luis Alberto Gómez

    2011-08-01

    componentes complementarios de la totalidad de las evidencias que permiten entender los determinantes de un estado de salud o de enfermedad. Los progresos en la definición de la relación de un evento biológico, ambiental, nutricional o social con el riesgo de desarrollar una enfermedad, están orientados por los desarrollos científicos y tecnológicos, así como por su incorporación en los bienes y servicios. En este escenario tan complejo, y para enfrentar los problemas actuales y por venir, la investigación científica en salud es una de las áreas de desarrollo con una gran responsabilidad de generar conocimiento científico, que permita orientar y proponer diferentes estrategias para atender problemas nuevos y futuros. La generación y la gestión del conocimiento en salud, como un factor de desarrollo y transformación del mundo moderno, determina que el Instituto Nacional de Salud, esté asumiendo un papel de liderazgo en la producción de ciencia y tecnología e innovación para contribuir a resolver problemas de salud, en concordancia con la realidad y las necesidades nacionales e internacionales. El Instituto Nacional de Salud ocupa una posición especial para dirigir y coordinar los esfuerzos colectivos e impulsar los cambios necesarios para aumentar la capacidad de investigación en salud, entre otros procesos de desarrollo. Con el objetivo de proporcionar un espacio para difundir la producción científico-técnica reciente en el campo de la salud humana, así como de promover y orientar la cooperación y transferencia de ciencia, tecnología e innovación en salud, el Instituto Nacional de Salud realiza el XII Encuentro Científico. En este encuentro se presentan algunos de los avances de las líneas institucionales y de los proyectos de investigación, con la participación de investigadores del Instituto y de algunos invitados nacionales e internacionales. Entre las principales áreas temáticas que se desarrollan se incluyen: redes y desarrollo en salud

  18. The GEKKO XII-HIPER (High Intensity Plasma Experimental Research) system relevant to ignition targets

    International Nuclear Information System (INIS)

    Miyanaga, N.; Nakatsuka, M.; Azechi, H.

    2001-01-01

    To test high gain targets surrogated in the planar geometry, we have constructed a new experimental system (HIPER) which provides the high ablation pressure with a uniform irradiance profile. These performances were achieved by bundling twelve beams of the existing GEKKO XII into a F/3 focus cone. The partially coherent light is introduced for the beam smoothing of a green foot pulse consisting of three beams, and the three-directional smoothing by spectral dispersion is utilized for residual nine beams delivering a blue main drive pulse. The detail of design concept and results of initial activation of this system are reported. (author)

  19. PENGARUH PRESTASI PRAKTIK KERJA INDUSTRI DAN HASIL BELAJAR KEWIRAUSAHAAN TERHADAP MINAT BERWIRAUSAHAAN SISWA KELAS XII AKUNTANSI SMK NEGERI 25 JAKARTA

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    DESTA AMBARSARI

    2016-03-01

    Full Text Available This research purpose is to find out the influence of industrial practice and entrepreneurship learning achievement to entrepreneurship interest, XII Accounting Class in SMK Negeri 25 Jakarta. This type of research is survey, with quantitative approach. Data recording, interview and questionnaire are research technique. Sampling technique used proportional random sampling. Total population in this study were 77 students with a sample of 64 students of XII accounting class in SMK Negeri 25 Jakarta. The results showed that: there is a significant positive influence of industrial practice and entrepreneurship learning achievement to entrepreneurship interest, XII Accounting Class in SMK Negeri 25 Jakarta. Thus if industrial practice and entrepreneurship learning achievement increases, the entrepreneurship interest will also increase.

  20. Ramsay Hunt syndrome with unilateral polyneuropathy involving cranial nerves V, VII, VIII, and XII in a diabetic patient.

    Science.gov (United States)

    Sun, Wei-Lian; Yan, Jian-Liang; Chen, Li-Li

    2011-01-01

    Ramsay Hunt syndrome is a rare complication of the varicella zoster virus, defined as a peripheral facial palsy that typically results from involvement of the facial and auditory nerves. Ramsay Hunt syndrome can be associated with cranial nerves V, VI, IX, and X but rarely with XII. We describe an atypical case of Ramsay Hunt syndrome with multiple cranial nerve involvement of nerves V, VII, VIII, and XII. Antiviral drugs, antibiotics, insulin, and traditional Chinese drugs were administered immediately after admission. After 3 months of combination therapy, the patient had recovered satisfactorily. Herpes zoster can cause severe infections in diabetic patients and should be treated as soon after detection as possible. Ramsay Hunt syndrome should be recognized as a polycranial neuritis characterized by damage to sensory and motor nerves. In addition to facial and vestibular nerve paralysis, Ramsay Hunt syndrome may also involve cranial nerves V and XII.

  1. Demonstration of resonant photopumping of Mo VII by Mo XII for a VUV laser near 600 Angstrom

    International Nuclear Information System (INIS)

    Ilcisin, K.J.; Aumayr, F.; Schwob, J.L.; Suckewer, S.

    1993-09-01

    We present data of experiments on the resonant photopumping of Mo VII by Mo XII as a method of generating a coherent VUV source near 600 angstrom. The experiment is based on a scheme proposed by Feldman and Reader in which the 4p 6 -- 4p 5 6s transition in Mo VII in resonantly photopumped by the 5s 2 S 1/2 -- 4p 2 P 1/2 transition in Mo XII. Results of the laser produced plasma experiments show the successful enhancement of the population of the Mo VII 4p 5 6s upper lasing level when pumped by an adjacent Mo VII plasma. No enhancement was seen in a control experiment where the Mo VII plasma was pumped by a Zr X plasma. Improvements of the intensity of the Mo XII pump source, achieved using an additional pump laser, lead to the generation of a population inversion for the VUV transition

  2. Progress in direct-drive laser fusion using GEKKO XII/PW facility

    International Nuclear Information System (INIS)

    Yamanaka, T.

    2002-01-01

    Extensive studies have been carried out for the fast-ignitor laser fusion which can provide one of the most feasible short tracks in the fusion energy development. We have upgraded the heating laser up to 1 PW(500 J/500 fs) and have started comprehensive studies on the transport of high current relativistic electron beam in the dense plasma. Substantial heating of the core plasma up to 1 keV is expected with implosion plasma produced by the Gekko XII laser. We have experimentally obtained for the first time all parameters to decide the growth rate of Rayleigh-Taylor instability using the HIPER irradiation system which can generate ablation pressure up to 60 Mbar and newly developed advanced x-ray diagnostic tools. We have proposed the FIREX (Fast Ignitor Realization Experiment) program for demonstrating the proof-of-principle of fast ignitor scheme. By the irradiation of ∼10 kJ/2-10 ps laser onto a DT core plasma formed by the GEKKO-XII, we are aiming at temperature of >8 keV and the fusion gain near unity. (author)

  3. Characterization and Sequencing of a Genotype XII Newcastle Disease Virus Isolated from a Peacock (Pavo cristatus) in Peru.

    Science.gov (United States)

    Chumbe, Ana; Izquierdo-Lara, Ray; Tataje-Lavanda, Luis; Figueroa, Aling; Segovia, Karen; Gonzalez, Rosa; Cribillero, Giovana; Montalvan, Angela; Fernández-Díaz, Manolo; Icochea, Eliana

    2015-07-30

    Here, we report the first complete sequence and biological characterization of a Newcastle disease virus (NDV) isolated from a peacock in South America (NDV/peacock/Peru/2011). This isolate, classified as genotype XII in class II, highlights the need for increased surveillance of noncommercial avian species. Copyright © 2015 Chumbe et al.

  4. 75 FR 37456 - Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of 2009

    Science.gov (United States)

    2010-06-29

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-55] Green Retrofit Program of... Affordable Housing Preservation must collect certain data to administer the Green Retrofit Program (GRP... Title of Proposal: Green Retrofit Program of Title XII of the American Recovery and Reinvestment Act of...

  5. HUBUNGAN PENGALAMAN PRAKTIK KERJA INDUSTRI DAN PRESTASI BELAJAR KEJURUAN DENGAN MINAT BERWIRAUSAHA SISWA KELAS XII TKR SMK COKROAMINOTO 2 BANJARNEGARA TAHUN PELAJARAN 2015/2016

    Directory of Open Access Journals (Sweden)

    Bayu Sandhi Pamungkas

    2016-06-01

    Results of this research is: (1 Industry experience working practices positively and significantly related with interest in entreprenuership class XII TKR student of SMK Cokroaminoto 2 Banjarnegara academic year 2015/2016; (2 Vocational learning achievement positively and significantly related with interest in entrepreneurship class XII TKR student of SMK Cokroaminoto 2 Banjarnegara academic year 2015/2016; (3 Industry experience working practices and vocational learning achievement  together positively and significantly related with interest in entrepreunership class XII TKR student of SMK Cokroaminoto 2 Banjarnegara academic year 2015/2016

  6. Le carte del monastero di S. Maria di Chiaravalle milanese. Additiones documentarie (secolo XII

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    Maria Cristina Piva

    2013-01-01

    Full Text Available Founded in 1135 in the immediate outskirts of Milan, Cistercian monastery of S. Maria di Chiaravalle was one of the most important ecclesiastical institutions in Lombardy. Since its foundation, it has played a prominent role in the political, religious, social and economic life of the city. In the Middle Ages the abbey distinguished itself with intensive production and preservation of documents, exemplified nowadays by the several hundreds of charterse preserved in the Archivio di Stato of Milan. This research aims to complete the organic reconstruction work, recently carried out by Anna Maria Rapetti and Ada Grossi regarding the XII century tabularium of Chiaravalle, with the critical edition of 28 unreleased documents dated between 1106 and 1164. In the introduction, in addition to the presentation of the documents, a paragraph will outline the historiographical balance of the studies conducted so far on the abbey.

  7. Summary of significant solar-initiated events during STIP interval XII

    International Nuclear Information System (INIS)

    Gergely, T.E.

    1982-01-01

    A summary of the significant solar-terrestrial events of STIP Interval XII (April 10-July 1, 1981) is presented. It is shown that the first half of the interval was extremely active, with several of the largest X-ray flares, particle events, and shocks of this solar cycle taking place during April and the first half of May. However, the second half of the interval was characterized by relatively quiet conditions. A detailed examination is presented of several large events which occurred on 10, 24, and 27 April and on 8 and 16 May. It is suggested that the comparison and statistical analysis of the numerous events for which excellent observations are available could provide information on what causes a type II burst to propagate in the interplanetary medium

  8. KETERAMPILAN MENULIS KREATIF CERPEN MENGGUNAKAN MEDIA AUDIO SISWA KELAS XII SMAN 1 KECAMATAN PAYAKUMBUH

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    Wirda Linda

    2017-04-01

    Full Text Available Writing skills is activities of language serves to produce  written language. Writing can improve intelligence, develop initiative, creativity,, stimulate the willingness and ability to gather information. Students' skills in short stories writing activities is still lacking. This things because teachers use less attractive media. Thus, this study uses audio media to increase students' interest in writing. This study aimed to describe the shost story intrinsic elements and the use of capital letters in Creative Short Story Writing Skills Using Media Audio Class XII SMAN I Payakumbuh District.This research is a quantitative research using descriptive method. The study population class XII students totaling 217 consists of 8 classes. Writer to perform sampling with random random sampling techniques. The instrument of this study is to test performance. Data analysis  in the study: to check the results to write short stories, analyze the data and provide a score based on indicators, and put forward the test results to the classification skills by using a scale of 10.Results showed that  average value of 90.8 are in the range of 86-95% with good qualification. Creative writing skills are evaluated from two short stories specified indicators are: (1 short story creative writing skills in terms of the intrinsic elements of the short story is the 100 that are in the range of 96-100% with impeccable qualifications; (2 The short story creative writing skills in terms of capitalization was 80.8% are in the 76-85 range with good qualifications. Thus, we can conclude the students are already capable in writing short stories as well as the use of capital letters in writing.    

  9. Opisthorchiasis in infant remains from the medieval Zeleniy Yar burial ground of XII-XIII centuries AD

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    Sergey Mikhailovich Slepchenko

    2015-01-01

    Full Text Available We present a paleoparasitological analysis of the medieval Zeleniy Yar burial ground of the XII-XII centuries AD located in the northern part of Western Siberia. Parasite eggs, identified as eggs of Opisthorchis felineus, were found in the samples from the pelvic area of a one year old infant buried at the site. Presence of these eggs in the soil samples from the infant’s abdomen suggests that he/she was infected with opisthorchiasis and imply consumption of undercooked fish. Ethnographic records collected among the population of the northern part of Western Siberia reveal numerous cases of feeding raw fish to their children. Zeleniy Yar case of opisthorchiasis suggests that this dietary custom has persisted from at least medieval times.

  10. Observation of solar radio bursts of type II and III at kilometer wavelengths from Prognoz-8 during STIP Interval XII

    International Nuclear Information System (INIS)

    Pinter, S.; Kecskemety, K.; Kudela, K.

    1982-04-01

    Type II and type III radio events were observed at low frequencies (2.16 MHz to 114 kHz) by the Prognoz-8 satellite during the period of STIP Interval XII in April and May, 1981, respectively. This review covers briefly a chronology of the sub-megahertz radio events, and where possible their association with both groundbased radio observations and solar flare. (author)

  11. XII ASSEMBLEIA GERAL ORDINÁRIA DO SÍNODO DOS BISPOS SOBRE A PALAVRA DE DEUS

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    Johan Konings

    2009-01-01

    Full Text Available Em outubro de 2008 transcorreu em Roma a XII Assembleia Geral Ordin ária do Sínodo dos Bispos, o qual é uma instituição permanente criada pelo Concílio Vaticano II para manter o diálogo dos pastores-bispos das Igrejas particulares. Nesta Assembleia, dedicada à Palavra de Deus na vida e na missão da Igreja, foi retomada praticamente a Constituição Dogmática Dei Verbum do Vaticano II. Depois de apresentar o tema da Palavra de Deus, traçamos um breve histórico focalizando os inícios da Tradição cristã e os tempos modernos desde Leão XIII até hoje. Em seguida descrevemos a XII Assembleia Geral, especialmente a Relatio post Disceptationem e as Propositiones. Concluímos com uma reflexão teológicopastoral sobre a Revelação e a leitura bíblica, e sugestões para a prática. ABSTRACT: In October of 2008 the XII Ordinary General Assembly of the Sinod of Bishops took place in Rome. The Sinod of Bishops is a permanent institution created by the II Vatican Council in order to maintain the dialogue of pastorsbishops of the particular Churches. This Assembly, dedicated to the Word of God in the life and in the mission of the Church, basically treated again the Dogmatic Constitution Dei Verbum of the II Vatican Council. After presenting the theme of the Word of God, we outline a brief history focusing on the beginnings of the Christian Tradition and the modern epoch since Leo XIII until today. Next we describe the XII General Assembly, especially the Relatio post Disceptationem and the Propostiones. We conclude with a theological-pastoral reflection on Revelation and the reading of the bible, and some practical suggestions.

  12. PENGEMBANGAN MEDIA AJAR LINE FOLLOWER ANALOG PADA MATA PELAJARAN PEREKAYASAAN SISTEM ROBOTIK KELAS XII TEKNIK ELEKTRONIKA INDUSTRI

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    Suwasono Suwasono

    2017-01-01

    Full Text Available This research aims at developing line follower analog media for robotic system engineering in SMKN 2 Singosari. The development was refered to modified model suggested by Sugiyono. The results of this development are in the form of modul, jobsheet, and trainer for robotic system engineering. The product was validated by content expertise I from Electrical Engineering Lecturer and obtained 92,06% of validity result. While the valifity result given the content expertise II from Robotic System Engineering teacher obtained 92,77%. In terms of media validity, the product obtained 94,81% from Electrical Engineering Lecturer and 94,02% from Robotic System Engineering Teacher. The product was also tested in XII Graders of Industry Electronics Engineering in SMKN 2 Singosari and obtained 88,20%. Thus, the media developed in the form of modul, jobsheet, and trainer of Robotic System Engineering within this study is considered as appropriate for XII Graders of Industry Electronics Engineering in SMKN 2 Singosari. Penelitian ini bertujuan untuk mengembangkan media ajar line follower analog pada mata pelajaran perekayasaan sistem robotik di SMKN 2 Singosari. Penelitian pengembangan mengacu pada model pengembangan Sugiyono yang dimodifikasi. Hasil pengembangan media ajar line follower analog berupa modul, jobsheet dan trainer untuk mata pelajaran Perekayasaan Sistem Robotik. Produk divalidasi ahli materi I dosen dari Jurusan Teknik Elektro memperoleh persentase sebesar 92,06%, ahli materi II dari guru mata pelajaran Perekayasaan Sistem Robotik memperoleh persentase sebesar 92,77%. Validasi media I dosen dari Jurusan Teknik Elektro memperoleh hasil persentase sebesar 94,81%, ahli media II dari guru mata pelajaran Perekayasaan Sistem Robotik memperoleh persentase sebesar 94,02%. Produk juga diujicobakan pada siswa kelas XII Teknik Elektronika Industri SMKN 2 Singosari diperoleh persentase sebesar 88,20% dan termasuk dalam kategori sangat layak. Sehingga produk

  13. Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure*

    Science.gov (United States)

    Agarwal, Pallavi; Zwolanek, Daniela; Keene, Douglas R.; Schulz, Jan-Niklas; Blumbach, Katrin; Heinegård, Dick; Zaucke, Frank; Paulsson, Mats; Krieg, Thomas; Koch, Manuel; Eckes, Beate

    2012-01-01

    The tensile and scaffolding properties of skin rely on the complex extracellular matrix (ECM) that surrounds cells, vasculature, nerves, and adnexus structures and supports the epidermis. In the skin, collagen I fibrils are the major structural component of the dermal ECM, decorated by proteoglycans and by fibril-associated collagens with interrupted triple helices such as collagens XII and XIV. Here we show that the cartilage oligomeric matrix protein (COMP), an abundant component of cartilage ECM, is expressed in healthy human skin. COMP expression is detected in the dermal compartment of skin and in cultured fibroblasts, whereas epidermis and HaCaT cells are negative. In addition to binding collagen I, COMP binds to collagens XII and XIV via their C-terminal collagenous domains. All three proteins codistribute in a characteristic narrow zone in the superficial papillary dermis of healthy human skin. Ultrastructural analysis by immunogold labeling confirmed colocalization and further revealed the presence of COMP along with collagens XII and XIV in anchoring plaques. On the basis of these observations, we postulate that COMP functions as an adapter protein in human skin, similar to its function in cartilage ECM, by organizing collagen I fibrils into a suprastructure, mainly in the vicinity of anchoring plaques that stabilize the cohesion between the upper dermis and the basement membrane zone. PMID:22573329

  14. Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.

    Science.gov (United States)

    Agarwal, Pallavi; Zwolanek, Daniela; Keene, Douglas R; Schulz, Jan-Niklas; Blumbach, Katrin; Heinegård, Dick; Zaucke, Frank; Paulsson, Mats; Krieg, Thomas; Koch, Manuel; Eckes, Beate

    2012-06-29

    The tensile and scaffolding properties of skin rely on the complex extracellular matrix (ECM) that surrounds cells, vasculature, nerves, and adnexus structures and supports the epidermis. In the skin, collagen I fibrils are the major structural component of the dermal ECM, decorated by proteoglycans and by fibril-associated collagens with interrupted triple helices such as collagens XII and XIV. Here we show that the cartilage oligomeric matrix protein (COMP), an abundant component of cartilage ECM, is expressed in healthy human skin. COMP expression is detected in the dermal compartment of skin and in cultured fibroblasts, whereas epidermis and HaCaT cells are negative. In addition to binding collagen I, COMP binds to collagens XII and XIV via their C-terminal collagenous domains. All three proteins codistribute in a characteristic narrow zone in the superficial papillary dermis of healthy human skin. Ultrastructural analysis by immunogold labeling confirmed colocalization and further revealed the presence of COMP along with collagens XII and XIV in anchoring plaques. On the basis of these observations, we postulate that COMP functions as an adapter protein in human skin, similar to its function in cartilage ECM, by organizing collagen I fibrils into a suprastructure, mainly in the vicinity of anchoring plaques that stabilize the cohesion between the upper dermis and the basement membrane zone.

  15. Pembelajaran Fisika Berbasis Kompetensi Life Skill Kelas XII IPA.1 MAN 1 Lampung Selatan

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    Poniman Poniman

    2016-04-01

    Full Text Available This study aims to determine the physics competency-based learning life skills class XII IPA1, It conducted in two cycles, each cycle consisting of four phases: planning, execution, analysis and reflection. The action used is "Competency-Based Physics Education Life Skills". The first cycle has not succeeded cognitive aspects obtained a mean value of 5.62, the affective with good criterion 32.35%, sufficient criteria 67.65% as well as psychomotor with good criterion 38.34%, sufficient criteria 61.66%, the life skill with all criteria 41.18%, both criteria 58.82 %.The second trying to provide intensive training with the same material, the result of learning on the cognitive of a mean value of 5.81, affective with both criteria of 76.47%, sufficient criteria 23.53%, psychomotor with good criterion 55.88%, sufficient criteria of 44.12% as well as on the life skill with very good criteria 1.76%. Penelitian ini bertujuan untuk mengetahui dampak pembelajaran fisika berbasis kompetensi life skill pada kelas XII IPA1. Penelitian ini dilakukan dalam dua siklus, setiap siklus terdiri dari empat tahap: perencanaan, pelaksanaan, analisis dan refleksi. Tindakan yang digunakan adalah "Pembelajaran isika Berbasis Kompetensi Life Skills ". Siklus pertama belum berhasil, nilai rata-rata aspek kognitif diperoleh 5,62; afektif dengan kriteria baik 32,35%, dan kriteria cukup 67,65%; serta psikomotorik dengan kriteria baik 38,34%, dan kriteria cukup 61.66%; life skills dengan semua kriteria 41,18%, kriteria baik 58,82%. siklus kedua mencoba untuk memberikan pelatihan intensif dengan tindakan yang sama, rata-rata hasil belajar aspek kognitif 5,81; afektif dengan kriteria baik 76,47%, kriteria cukup 23,53% , psikomotor dengan kriteria baik 55,88%, kriteria cukup 44,12% serta pada life skill dengan kriteria baik sekali 1,76%. Kata kunci: pembelajaran fisika, physics competency-based learning life skills

  16. Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis.

    Science.gov (United States)

    Kleinschnitz, Christoph; Braeuninger, Stefan; Pham, Mirko; Austinat, Madeleine; Nölte, Ingo; Renné, Thomas; Nieswandt, Bernhard; Bendszus, Martin; Stoll, Guido

    2008-04-01

    Models of photochemically-induced thrombosis are widely used in cerebrovascular research. Photothrombotic brain infarctions can be induced by systemic application of photosensitizing dyes followed by focal illumination of the cerebral cortex. Although the ensuing activation of platelets is well established, their contribution for thrombosis and tissue damage has not formally been proved. Infarction to the cerebral cortex was induced in mice by Rose Bengal and a cold light source. To assess the functional role of platelets, animals were platelet-depleted by anti-GPIbalpha antibodies or treated with GPIIb/IIIa-blocking F(ab)(2) fragments. The significance of the plasmatic coagulation cascade was determined by using blood coagulation factor XII (FXII)-deficient mice or heparin. Infarct development and infarct volumes were determined by serial MRI and conventional and electron microscopy. There was no difference in development and final size of photothrombotic infarctions in mice with impaired platelet function. Moreover, deficiency of FXII, which initiates the intrinsic pathway of coagulation and is essential for thrombus formation, or blockade of FXa, the key protease during the waterfall cascade of plasmatic coagulation, by heparin likewise did not affect lesion development. Our data demonstrate that platelet activation, factor XII-driven thrombus formation, and plasmatic coagulation pathways downstream of FX are not a prerequisite for ensuing tissue damage in models of photothrombotic vessel injury indicating that other pathomechanisms are involved. We suggest that this widely used model does not depend on platelet- or plasmatic coagulation-derived thrombosis.

  17. Gambaran Strategi Coping Stress Siswa Kelas XII Sman 42 Jakarta dalam Menghadapi Ujian Nasional

    Directory of Open Access Journals (Sweden)

    Muhamad Nanang Suprayogi

    2011-04-01

    Full Text Available This study intended to know the description of stress coping strategies of 12th grade students of Jakarta 42 State Senior High School in facing National Exam. This study stems from the interest of researchers towards the number of cases of high school students who do not pass the National Exam. Researchers seek to impart knowledge to students on how to cope with their stress effectively and to the school and parents for providing the proper approach for students to face the National Exam. This study is a quantitative study using questionnaires as a measurement to know the description of stress coping strategies of Jakarta 42 State Senior High School students. Research instruments are compiled based on the theory developed by Lahey. In this research, obtained results that the class XII students of SMAN 42 Jakarta have a more predominant use of effective coping to cope with their stress in facing the National Exam. The most widely used strategy is removing stress and managing stress reaction  

  18. Hubungan Kematangan Emosi dengan Pengambilan Keputusan Karir pada Siswa Kelas XII SMA

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    Yashinta Rizky Ananda

    2017-08-01

    Full Text Available This research is done because the phenomenon in Senior High School 1 Mijen-Demak. Based on the record of events, it’s found that students of XII class have not seen the emotional maturity and the decision making of career after graduation. The purpose of this research is to find out relation of the emotional maturity and the career decision making. This research is an ex post facto with the quantitative correlation method. The samples used in this research are 114 students. The data collection that is used the emotional maturity and career decision making scale. The data analysis that is used the descriptive percentage and product moment correlation. The research result shows that 99 of students have the high emotional maturity, 98 of the students have the high decision making of career skill, and the sig is 0,000=0%, less than α=5% with r=0,348. There is a significant relation between the emotional maturity and the decision making of career in the low level of relationship. So, it can be said that the Ho is rejected and the Ha is accepted.

  19. SOME CHURCH MANAGEMENT IN THE PRINCIPALITY SOUTHEAST RUSSIA IN XI-XII CENTURIES

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    Наталья Вячеславовна Логачёва

    2014-12-01

    Full Text Available This paper shows that the joint cooperation of church and state in the principalities of South-Eastern XI-XII centuries. Emphasizes that the problem is not only scientific but also of practical interest for the modern Russian society. This experience is for national history an invaluable contribution to the field, both secular and ecclesiastical administration in feudal principalities and Old Russian state as a whole. Particular attention is paid to the analysis of the process of establishing the relationship between church and state, which were formed, changed and improved over the centuries. In particular, the article says that the medieval relations between church and state were more active and expressed that the church served a number of public functions and is thus, a special part of government agencies and their authorities. At the same time, the author notes that the church was in this historical financial content of the state apparatus. In view of this church-state relations in ancient Russia, primarily in the South-East of Russia, wore a special character - the church was interested in the state, and the state - in the church.

  20. Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcome

    International Nuclear Information System (INIS)

    Yoo, Chong Woo; Nam, Byung-Ho; Kim, Joo-Young; Shin, Hye-Jin; Lim, Hyunsun; Lee, Sun; Lee, Su-Kyoung; Lim, Myong-Cheol; Song, Yong-Jung

    2010-01-01

    To investigate whether expression of carbonic anhydrase XII (CA12) is associated with histologic grade of the tumors and radiotherapy outcomes of the patients with invasive cervical cancer. CA12 expression was examined by immunohistochemical stains in cervical cancer tissues from 183 radiotherapy patients. Histological grading was classified as well (WD), moderately (MD) or poorly differentiated (PD). Oligonucleotide microarray experiment was performed using seven cervical cancer samples to examine differentially expressed genes between WD and PD cervical cancers. The association between CA12 and histological grade was analyzed by chi-square test. CA12 and histological grades were analyzed individually and as combined CA12 and histologic grade categories for effects on survival outcome. Immunohistochemical expression of CA12 was highly associated with the histologic grade of cervical cancer. Lack of CA12 expression was associated with PD histology, with an odds ratio of 3.9 (P = 0.01). Microarray analysis showed a fourfold reduction in CA12 gene expression in PD tumors. CA12 expression was marginally associated with superior disease-free survival. Application of the new combined categories resulted in further discrimination of the prognosis of patients with moderate and poorly differentiated tumor grade. Our study indicates that CA12 may be used as a novel prognostic marker in combination with histologic grade of the tumors

  1. Development of Instructional Materials for Electrochemical Module Class XII Science High School Students with Guided Inquiry Learning Approach

    Directory of Open Access Journals (Sweden)

    Lilik Fatmawati

    2014-06-01

    Full Text Available Pengembangan Bahan Ajar Modul Elektrokimia untuk Siswa SMA Kelas XII IPA dengan Pendekatan Pembelajaran Inkuiri Terbimbing Abstract: The aim of this study was to determine the feasibility and effectiveness of the electrochemical module for high school students of class XII results of development. Electrochemical module of the development consists of two learning activities, ie to the material Volta cells and electrolysis cells for the material. Results of the assessment by two chemistry lecturer, State University of Malang and two chemistry teachers XII as an expert content / learning material for eligibility contents was 92.9%, for eligibility and completeness of presentation is 91.1%, and for the eligibility of language is 92.3% , which is classified as very feasible criteria. Overall the average value was 92.1 feasibility. Effectiveness module is indicated by the results of the development of perception and student learning outcomes. Students' perceptions obtained from student assessment results to module development. In the limited field trials obtained average value is 81.8 for all aspects of the maximum value of 100. Obtaining the average value of student learning outcomes for the cognitive aspect is 83.3, for the affective aspect is 82.3, and for the psychomotor aspect is 83.8 out of 100. The maximum value of the overall results of the study showed that the electrochemical module for high school students Class XII Science development results are very decent and very effectively used in the learning process. Key Words: guided inquiry, electrochemical module, model 4-D Abstrak: Tujuan penelitian ini adalah mengetahui kelayakan, dan keefektifan modul elektrokimia untuk siswa SMA kelas XII hasil pengembangan. Modul Elektrokimia hasil pengembangan terdiri dari dua kegiatan belajar, yaitu untuk materi sel Volta dan untuk materi sel elektrolisis. Hasil penilaian oleh dua dosen kimia Universitas Negeri Malang dan dua guru kimia kelas XII sebagai

  2. PENGARUH STRATEGI PEMBELAJARAN PRAKTIKUM SIFAT KOLIGATIF TERHADAP HASIL BELAJAR SISWA KELAS XII

    Directory of Open Access Journals (Sweden)

    Muhammad Hubbi

    2017-01-01

    belajar siswa kelas XII IPA Madrasah Aliyah Ma’arif 7 Lamongan pada materi sifat koligatif larutan. Hasil belajar berupa nilai yang berasal laporan hasil praktikum dan tes tulis. Subyek penelitian ini adalah 34 siswa kelas XII-E IPA Madrasah Aliyah Ma’arif 7 Lamongan tahun pelajaran 2015-2016. Rancangan penelitian yang digunakan adalah the one group pretest-posttest. Instrumen penelitian menggunakan tes tulis dan lembar observasi. Tes tulis untuk mengukur hasil belajar divalidasi sebelum digunakan dan memiliki reliabilitas 0,802. Data yang diperoleh selanjutnya dianalisis dengan analisis deskriptif dan uji beda. Uji beda menggunakan uji t-paired. Hasil uji-t berpasangan diperoleh sig 0,000 yang berarti lebih kecil dari 0,05 sehingga H0 ditolak dengan reliabilitas 95%. Berdasarkan hasil tersebut dapat disimpulkan bahwa terdapat peningkatan hasil belajar yang signifikan pada pembelajaran praktikum dengan menggunakan prosedur praktikum sifat koligatif larutan. Nilai rata-rata hasil belajar siswa meningkat dari 61,05 menjadi 81,44. Peningkatan ini menunjukkan pembelajaran praktikum berbasis inkuiri terbimbing memiliki tingkat efektivitas yang baik.

  3. PENGARUH MOTIVASI BELAJAR EKONOMI, GENDER DAN LINGKUNGAN PONDOK PESANTREN (SUNAN PANDANARAN TERHADAP PERILAKU BELAJAR EKONOMI SISWA DI KELAS PADA SISWA KELAS XII IPS PUTRA DAN XII IPS PUTRI MA SUNAN PANDANARAN SLEMAN, YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Siti Masruroh

    2015-11-01

    Full Text Available Penelitian ini bertujuan untuk menguji pengaruh motivasi belajar ekonomi, gender dan lingkungan pondok pesantren (Sunan Pandanaran terhadap perilaku belajar ekonomi siswa di kelas baik secara simultan maupun parsial. Populasi dan sampel pada penelitian ini adalah siswa kelas XII IPS Putra dan siswi kelas XII IPS Putri. Metode pengumpulan data dalam penelitian ini menggunakan metode angket/kuesioner. Variabel dependen pada penelitian ini yaitu perilaku belajar ekonomi siswa di kelas. Variabel independennya yaitu motivasi belajar ekonomi, gender dan lingkungan pondok pesantren (Sunan Pandanaran. Hasil uji hipotesis simultan menunjukkan bahwa ada pengaruh motivasi belajar ekonomi, gender dan lingkungan pondok pesantren (Sunan Pandanaran terhadap perilaku belajar ekonomi siswa di kelas. Hasil uji hipotesis secara parsial menunjukkan bahwa ada pengaruh motivasi belajar ekonomi terhadap perilaku belajar ekonomi siswa di kelas, ada pengaruh gender terhadap perilaku belajar ekonomi siswa di kelas dan ada pengaurh lingkungan pondok pesantren (Sunan Pandanaran terhadap perilaku belajar ekonomi siswa di kelas. Simpulan dari penelitian ini yaitu motivasi belajar ekonomi, gender dan lingkungan pondok pesantren (Sunan Pandanaran berpengaruh terhadap perilaku belajar ekonomi siswa di kelas baik secara simultan maupun secara parsial. Untuk penelitian selanjutnya diharapkan dapat menggunakan variabel lain yang tidak digunakan dalam penelitian ini seperti minat terhadap mata pelajaran ekonomi dan dukungan orang tua yang secara parsial maupun simultan dapat berpengaruh terhadap perilaku belajar ekonomi siswa di kelas. This study aimed to examine the effect of learning motivation economic, gender and environmental Boarding Sunan Pandanaran the behavior of students in the classroom studying economics either simultaneously or partially. Population and sample in this research were students of class XII IPS grader son and daughter XII IPS. Data collection method in

  4. Mutations in the collagen XII gene define a new form of extracellular matrix-related myopathy.

    Science.gov (United States)

    Hicks, Debbie; Farsani, Golara Torabi; Laval, Steven; Collins, James; Sarkozy, Anna; Martoni, Elena; Shah, Ashoke; Zou, Yaqun; Koch, Manuel; Bönnemann, Carsten G; Roberts, Mark; Lochmüller, Hanns; Bushby, Kate; Straub, Volker

    2014-05-01

    Bethlem myopathy (BM) [MIM 158810] is a slowly progressive muscle disease characterized by contractures and proximal weakness, which can be caused by mutations in one of the collagen VI genes (COL6A1, COL6A2 and COL6A3). However, there may be additional causal genes to identify as in ∼50% of BM cases no mutations in the COL6 genes are identified. In a cohort of -24 patients with a BM-like phenotype, we first sequenced 12 candidate genes based on their function, including genes for known binding partners of collagen VI, and those enzymes involved in its correct post-translational modification, assembly and secretion. Proceeding to whole-exome sequencing (WES), we identified mutations in the COL12A1 gene, a member of the FACIT collagens (fibril-associated collagens with interrupted triple helices) in five individuals from two families. Both families showed dominant inheritance with a clinical phenotype resembling classical BM. Family 1 had a single-base substitution that led to the replacement of one glycine residue in the triple-helical domain, breaking the Gly-X-Y repeating pattern, and Family 2 had a missense mutation, which created a mutant protein with an unpaired cysteine residue. Abnormality at the protein level was confirmed in both families by the intracellular retention of collagen XII in patient dermal fibroblasts. The mutation in Family 2 leads to the up-regulation of genes associated with the unfolded protein response (UPR) pathway and swollen, dysmorphic rough-ER. We conclude that the spectrum of causative genes in extracellular matrix (ECM)-related myopathies be extended to include COL12A1.

  5. Intrinsic clotting factors in dependency of age, sex, body mass index, and oral contraceptives: definition and risk of elevated clotting factor levels.

    Science.gov (United States)

    Luxembourg, Beate; Schmitt, Joern; Humpich, Marek; Glowatzki, Matthias; Seifried, Erhard; Lindhoff-Last, Edelgard

    2009-10-01

    Elevated clotting factors have been demonstrated to be a risk factor for venous thromboembolism (VTE). The aim of our study was to investigate the impact of age, sex, body mass index, and oral contraceptives on the clotting factor activities of factors VIII, IX, XI, and XII and their impact on the cutoff definition and risk of VTE associated with elevated clotting factors. Factor VIII, IX, XI, and XII activities were measured in 499 blood donors and 286 patients with VTE. Age and body mass index predicted significantly and independently the clotting factor activities of factors VIII, IX, and XI, whereas use of oral contraceptives predicted factor IX, XI, and XII levels. Percentiles of clotting factor activities, which are often used for the cutoff definition of elevated clotting factors, varied due to the effect of age, body mass index, and oral contraceptives. The adjusted odds ratios for VTE were 10.3 [95% confidence interval (CI) 5.1-20.7], 6.1 (95% CI 3.1-12.0), and 3.3 (95% CI 1.9-5.8) for elevated factors VIII, IX, and XI, respectively. Furthermore, our study demonstrates for the first time that elevated factor XII is associated with an increased risk of VTE (adjusted odds ratio 2.9, 95% CI 1.6-5.3).

  6. Pathotyping and Phylogenetic Characterization of Newcastle Disease Viruses Isolated in Peru: Defining Two Novel Subgenotypes Within Genotype XII.

    Science.gov (United States)

    Chumbe, Ana; Izquierdo-Lara, Ray; Tataje, Luis; Gonzalez, Rosa; Cribillero, Giovana; González, Armando E; Fernández-Díaz, Manolo; Icochea, Eliana

    2017-03-01

    Infections of poultry with virulent strains of avian paramyxovirus 1 (APMV-1), also known as Newcastle disease viruses (NDVs), cause Newcastle disease (ND). This highly contagious disease affects poultry and many other species of birds worldwide. In countries where the disease is prevalent, constant monitoring and characterization of isolates causing outbreaks are necessary. In this study, we report the results of pathogenicity testing and phylogenetic analyses of seven NDVs isolated from several regions of Peru between 2004 and 2015. Six viruses had intracerebral pathogenicity indices (ICPIs) of between 1.75 and 1.88, corresponding to a velogenic pathotype. The remaining virus had an ICPI of 0.00, corresponding to a lentogenic pathotype. These results were consistent with amino acid sequences at the fusion protein (F) cleavage site. All velogenic isolates had the polybasic amino acid sequence 112 RRQKR↓F 117 at the F cleavage site. Phylogenetic analyses of complete F gene sequences showed that all isolates are classified in class II of APMV-1. The velogenic viruses are classified in genotype XII, while the lentogenic virus is classified in genotype II, closely related to the LaSota vaccine strain. Moreover, tree topology, bootstrap values, and genetic distances observed within genotype XII resulted in the identification of novel subgenotypes XIIa (in South America) and XIIb (in China) and possibly two clades within genotype XIIa. All velogenic Peruvian viruses belonged to subgenotype XIIa. Overall, our results confirm the presence of genotype XII in Peru and suggest that it is the prevalent genotype currently circulating in our country. The phylogenetic characterization of these isolates helps to characterize the evolution of NDV and may help with the development of vaccines specific to our regional necessities.

  7. XII All-Russian conference Diagnostics of high-temperature plasma. Abstracts of reports and conference program

    International Nuclear Information System (INIS)

    2007-01-01

    Abstracts of reports made on the XII All-Russian conference on high-temperature plasma diagnostics are presented. The different methods of hot plasma diagnostics are considered, namely microwave diagnostic methods, laser diagnostic techniques, X-ray plasma diagnostics and corpuscular diagnostic methods. The particular attention is given to wall plasma diagnostics and diagnostics of inertial synthesis systems. Current diagnostic tools and metrological provision for plasma diagnostics are considered. The diagnostic complexes of thermonuclear devices are described. The problems of experimental data processing are discussed [ru

  8. Geothermal Program Review XII: proceedings. Geothermal Energy and the President's Climate Change Action Plan

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-31

    Geothermal Program Review XII, sponsored by the Geothermal Division of US Department of Energy, was held April 25--28, 1994, in San Francisco, California. This annual conference is designed to promote effective technology transfer by bringing together DOE-sponsored researchers; utility representatives; geothermal energy developers; suppliers of geothermal goods and services; representatives from federal, state, and local agencies; and others with an interest in geothermal energy. In-depth reviews of the latest technological advancements and research results are presented during the conference with emphasis on those topics considered to have the greatest potential to impact the near-term commercial development of geothermal energy.

  9. Pengembangan Modul Pembelajaran Fisika Berbasis Problem Based Learning (PBL pada Materi Gelombang Bunyi untuk Siswa SMA Kelas XII

    Directory of Open Access Journals (Sweden)

    Tri Anita Nur Hasanah

    2017-03-01

    Full Text Available The 2013 curriculum emphasizes on Scientific Approach taht tie topic with real context. Either learning model that leads to Scientific Approach that is Problem Based Learning (PBL. So that need to prepare appropriate teaching material to support learning model PBL one of them module independent teaching topic for learners. The aim of these research is describe the Learning Module which is developed that is physic learning module based on PBL of the topic sound wave for senior high school grade XII and examine its feasibility. This development research used 4-D Thiagarajan with modified model. This research has been done in three stages such as define, design, and develop which are restricted until the limited try out. The data collection is used questionnaire. The module validation by 4 validators and limited try out to 10 students. The result of research drawn that material aspect is 3,59 with the suitable criterion, presentation aspect is 3,9 with the suitable criterion, language aspect is 3,41 with the suitable criterion, and the limited try out result got 3,6 with an appropriate criterion. In conclusion, physic learning module based on PBL in sound wave material for senior high school grade XII is applicable. Keywords: Physic Learning Module, Problem Based Learning (PBL, Topic sound wave Pada kurikulum 2013 menekankan pada Scientific Approach yang mengaitkan materi dengan konteks dunia nyata. Salah satu model pembelajaran yang mengarah ke Scientific Approach yaitu Problem Based Learning (PBL. Sehingga perlu dipersiapkan bahan ajar yang tepat untuk mendukung model pembelajaran PBL salah satunya modul yang merupakan bahan ajar mandiri bagi peserta didik. Tujuan penelitian ini adalah mendeskripsikan pengembangan modul yaitu modul pembelajaran fisika berbasis PBL pada materi Gelombang Bunyi untuk siswa SMA kelas XII dan menguji kelayakannya.Penelitian pengembangan menggunakan model 4-D Thiagarajan yang sudah di modifikasi. Penelitian ini

  10. 77 FR 29633 - Alta Wind VII, LLC, Alta Wind IX, LLC, Alta Wind X, LLC, Alta Wind XI, LLC, Alta Wind XII, LLC...

    Science.gov (United States)

    2012-05-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-68-000] Alta Wind VII, LLC, Alta Wind IX, LLC, Alta Wind X, LLC, Alta Wind XI, LLC, Alta Wind XII, LLC, Alta Wind XIII, LLC, Alta Wind XIV, LLC, Alta Wind XV, LLC, Alta Windpower Development, LLC, TGP Development Company, LLC...

  11. Evaluation of 177Lu[Lu]-CHX-A″-DTPA-6A10 Fab as a radioimmunotherapy agent targeting carbonic anhydrase XII.

    Science.gov (United States)

    Fiedler, L; Kellner, M; Gosewisch, A; Oos, R; Böning, G; Lindner, S; Albert, N; Bartenstein, P; Reulen, H-J; Zeidler, R; Gildehaus, F J

    2018-05-01

    Due to their infiltrative growth behavior, gliomas have, even after surgical resection, a high recurrence tendency. The approach of intracavitary radioimmunotherapy (RIT) is aimed at inhibiting tumor re-growth by directly administering drugs into the resection cavity (RC). Direct application of the radioconjugate into the RC has the advantage of bypassing the blood-brain barrier, which allows the administration of higher radiation doses than systemic application. Carbonic anhydrase XII (CA XII) is highly expressed on glioma cells while being absent from normal brain and thus an attractive target molecule for RIT. We evaluated a CA XII-specific 6A10 Fab (fragment antigen binding) labelled with 177 Lu as an agent for RIT. 6A10 Fab fragment was modified and radiolabelled with 177 Lu and characterized by MALDI-TOF, flow cytometry and radio-TLC. In vitro stability was determined under physiological conditions. Biodistribution studies, autoradiography tumor examinations and planar scintigraphy imaging were performed on SCID-mice bearing human glioma xenografts. The in vitro CA XII binding capacity of the modified Fab was confirmed. Radiochemical purity was determined to be >90% after 72 h of incubation under physiological conditions. Autoradiography experiments proved the specific binding of the Fab to CA XII on tumor cells. Biodistribution studies revealed a tumor uptake of 3.0%ID/g after 6 h and no detectable brain uptake. The tumor-to-contralateral ratio of 10/1 was confirmed by quantitative planar scintigraphy. The radiochemical stability in combination with a successful in vivo tumor uptake shows the potential suitability for future RIT applications with the 6A10 Fab. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Soft x-ray amplification in lithium-like Al XI (154 /angstrom/) and Si XII (129 /angstrom/)

    International Nuclear Information System (INIS)

    Kim, D.; Skinner, C.H.; Wouters, A.; Valeo, E.; Voorhees, D.; Suckewer, S.

    1988-03-01

    Recent experiments on soft x-ray amplification in lithium-like ions in a CO 2 laser-produced recombining plasma confined in a magnetic field are presented. The maximum gain-length products observed are GL ≅ 3 to 4 for the 154 /angstrom/, 4f-3d transition in Al XI and GL (approxreverse arrowequal/ 1 to 2 for the 129 /angstrom/, 4f-3d transition in Si XII, respectively. A one-dimensional hydrodynamic code with a collisional-radiative atomic model was used to model the plasma and the theoretical predictions of gain agree well with the observations. Descriptions of both hydrodynamic and atomic physics code are given. 36 refs., 10 figs

  13. Influencia de la historia de España (del siglo XII al XIX en el periodismo especializado en ciencia

    Directory of Open Access Journals (Sweden)

    Dr. Carlos Elías

    2001-01-01

    Full Text Available El periodismo especializado en ciencia y tecnología en España no ha alcanzado los niveles de los países anglosajones. Ello se pone de manifiesto no sólo por la relativa ausencia de suplementos destinados a ciencia en los periódicos generalistas sino, sobre todo, por la ausencia de portales de Internet en los que se divulgue la ciencia en español así como los logros en este campo de la comunidad hispana. Pero esta circunstancia no es casual: es el producto de una historia, la de la ciencia en España, que siempre ha tenido muchos detractores, entre ellos la iglesia. En este artículo se analiza cómo influyó la historia de España desde el siglo XII hasta principios del XIX en el actual periodismo especializado en ciencia.

  14. Proceedings of VI International Symposium on Nuclear and Related Techniques. XII Workshop on Nuclear Physics. WONP-NURT 2009

    International Nuclear Information System (INIS)

    2009-02-01

    This year the XII Workshop on Nuclear Physics (WONP) and the VI Symposium on Nuclear and Related Techniques (NURT) are organized jointly, by Instituto Superior de Tecnologias y Ciencias Aplicadas and Centro de Aplicaciones Tecnologicas y Desarrollo Nuclear. Both events gather scientists from several countries with top research work on nuclear physics and its applications. WONP has been carried out since 1994 promoting an ever-exchanging exchange between professionals of various nuclear and applied physics fields, those related to environmental and health care. NURT is one of the key Cuban scientific meetings since 1997 dealing with the peaceful applications of nuclear techniques in several domains of the society. WONP and NURT provide an unique opportunity for the national and international scientific community to meet outstanding researchers and discuss current trends in several areas of theoretical, experimental and applied nuclear physics and related topics. The papers submitted to this event are presented in this CD-ROM

  15. Voyages of a successful text. The Dialogi of Gregory the Great in Medieval Sicily (XII-XIV Century

    Directory of Open Access Journals (Sweden)

    Rossana Barcellona

    2013-10-01

    Full Text Available This essay reconstructs two “Sicilian chapters” of great success from the Dialogi by Gregorius Magnus which were enjoyed in the medieval era. These are the legend of Placido (Placido is a Benedict's young disciple mentioned in the Dialogi, which has Sicily as a background, as recounted by Pietro, Deacon of Montecassino between the XI and the XII centuries, and the Sicilian vulgarization of the work, carried out by Giovanni Campolo in the first half of the XIV century. The literary voyage of Placido and the work of Campolo are two excellent examples of the circulation and the fruition of an exemplary and authoritative text. Each highlights the complex intricacy of religion, culture and politics in the various systems of power and in the various historical settings that the medieval age explored.

  16. Pengaruh Komunikasi, Kepemimpinan dan Motivasi Kerja Terhadap Kinerja Karyawan Studi Pada Kantor Wilayah XII Direktorat Jenderal Kekayaan Negara (DJKN Banjarmasin

    Directory of Open Access Journals (Sweden)

    Andi Susanto

    2016-04-01

    Full Text Available This research aims to fi nd out and analyze the infl uence among communication (X1, leadership (X2, and work motivation (X3 as indefendent variables either partially or simultaneously toward employee’s performance (Y as dependent variable at Kantor Wilayah XII DJKN Banjarmasin. The method of this research used questionnaire with 32 employees of Kantor Wilayah  XII  DJKN  Banjarmasin  as  a  sample  and  it  has  been  selected  from population  as  45  emplyees.  The  variables  measurement  uses  Likert’s  Scale technique with weighting scale from 1 to 5. To fi nd out the correlation among variables X1 X2 X3 towards Y uses statistical technique of correlation analysis,  multiple linear regression and to test the signifi cance rate uses F test and t test processed with SPSS Program. The  result  of  research  concludes  that  there  is  a  positive  signifi cant  infl uence from each indefendent variable’s toward the dependent variable. From the three indefendent  variables,  the  highest  percentage  (25.9%  is  the  communication (X1  as  compared  with  the  two  other  independent  variables.  And  there  is  a signifi cant  simultaneously  infl uence  from  the  three  independent  variables toward the variable of employee’s performance. Keyword :Communication, leadership, work motivation, performance.

  17. Castillos, poder feudal y reorganización espacial en la Transierra madrileña (siglos XII-XIII

    Directory of Open Access Journals (Sweden)

    Iñaki Martín Viso

    2000-01-01

    Full Text Available Algunos castillos de la Transierra madrileña en los siglos xii y xiii son herederos de los husün musulmanes, pero se convierten en esa época en centros de poder señorial sobre unas débiles comunidades. No obstante, sólo su transformación en concejos permitirá la supervivencia de algunos de ellos, aunque se observa también un desplazamiento del habitat hacia el llano, resultado de la formación de un nuevo sistema productivo basado en la agricultura cerealfstica y la propiedad feudal, por lo que el papel de los castillos es limitado. En las zonas serranas su relevancia es aún menor y nunca estructuraron el paisaje, labor que ejercieran los sexmos de la Tierra de Segovia.Some castles of the Madrid's Transierra in the xii"" and xiif" centuries are inheritors of the muslim husün, but they viere converted during this age in centres of a lordship power which was imposed to the weak communities. However, only some of them could survive through their conversión In town counciis (concejos, although there is also an habitat's displacement to the plain, that is the result of the new producing system based on the grain agrículture and the feudal property, so the role of the castles was reduced. In the mountain áreas the landscape was never structured by castles, but by the rural distrícts (sexmos ofthe Segovia's Land.

  18. PREFACE: XII Latin American workshop on plasma physics (17-21 September 2007, Caracas, Venezuela)

    Science.gov (United States)

    Puerta, Julio

    2008-10-01

    Some years ago a group of Latin American physicists took the initiative to consult about the viability of organizing a meeting on plasma physics for researchers and students of the region. The result was that it was not only a good idea, but a necessity in order to show and share everyone's work, and to keep updated on latest advances and technologies on plasma physics. It was decided that for new researchers as well as students of Physics, it would prove to be the best way to keep them posted on such matters. This was the birth of a series of meetings known as Latin American workshops on plasma physics that take place every two years in a different Latin American country. In Venezuela we have had the opportunity to organize two editions of this interesting and important reunion of physicists. The first of these Latin American workshops on plasma physics was held in Cambuquira (Brazil) in 1982. After organizing the first six editions of the workshop, the VII LAWPP meeting was realized in Caracas in January 1997. It was designed with a structure similar to the first edition. It developed in two stages, a first week devoted to short courses with lecturers in different fields of plasma physics and a second week for contributed and invited presentations. Participants from sixteen different countries were present, half of them from this continent and the other half from overseas, demonstrating the international character of this meeting. There have been four more editions of the workshop and once again, we have had the opportunity to organize this latest edition of the series: the XII Latin American workshop on plasma physics, which took place in Caracas, Venezuela from the 17th to the 21st of September 2007. The structure was modified, because contributed and review papers were together during the first stage, with short courses realized during the second one, called mini-courses, and given by several high level contributors such as José Boedo, Leopoldo Soto, Claude

  19. HUBUNGAN PENGALAMAN PRAKTIK KERJA INDUSTRI DAN PRESTASI BELAJAR KEJURUAN DENGAN MINAT BERWIRAUSAHA SISWA KELAS XII TKR SMK COKROAMINOTO 2 BANJARNEGARA TAHUN PELAJARAN 2015/2016

    OpenAIRE

    Bayu Sandhi Pamungkas; Pairun Roniwijaya

    2016-01-01

    The Relationship of Practices Industry Experience and Vocational Learning Achievement with Interest in Entrepreneurship Class XII TKR student of  SMK Cokroaminoto 2 Banjarnegara  academic year 2015/2016. Thesis Study Program of Mechanical Engineering Faculty of Teacher Training and Educational Sciences Sarjanawiyata Tamansiswa University Yogyakarta 2016. The purpose of this research is: (1) to determine the relationship of Industry Experience Working Practices with interest in entreprenue...

  20. The Effect of Industrial Work Performance Practice and Performance Automotive Electrical Prakti entrepreneurial n Against Interests Automotive Mechanics Class XII Smk Diponegoro Depok Sleman

    OpenAIRE

    Arif Mustofa; Pairun Roniwijaya

    2013-01-01

    The purpose of this study was to determine (1) the influence of the industrial working practices achievement entrepreneurial interests, (2) the effect of automotive electrical practice achievement against entrepreneurial interests, and (3) influence of achievement and accomplishment industry work practices automotive electrical practices to entrepreneurial interest Automotive Mechanics XII class students of SMK Diponegoro Depok Sleman school year 2012/2013.  The results showed that the test r...

  1. El castillo de Portilla (Zambrana, Álava: Origen y significado de una fortaleza plenomedieval en territorio alavés (siglos XI-XII

    Directory of Open Access Journals (Sweden)

    Jose Luis Solaun Bustinza, Agustín Azkarate Garai-Olaun

    2016-01-01

    Las recientes investigaciones arqueológicas efectuadas en esta fortaleza han permitido conocer mejor su origen y significado. Las evidencias apuntan a que la actual fortaleza, construida entre principios del siglo XI y mediados del siglo XII, estuvo bajo titularidad real, aunque fue gestionada por importantes aristocracias locales y regionales, siendo testigo de las complejas relaciones entre el poder público y privado y, obviamente, de la multiplicidad de funciones que esta fortaleza pudo desempeñar.

  2. ANALISIS NILAI – NILAI PENDIDIKAN KARAKTER PADA NOVEL SUTASOMA KARYA COK SAWITRI DAN RELEVANSINYA DENGAN PEMBELAJARAN BAHASA INDONESIA KELAS XII

    Directory of Open Access Journals (Sweden)

    Sariasih Sariasih

    2017-10-01

    Full Text Available Tujuan penelitian ini adalah mendeskripsikan: (1 Nilai-nilai Penddikan Karakter Novel Sutasoma karya Cok Sawitri, (2 Struktur novel Sutasoma karya Cok Sawitri, dan (3 Relevansi nilai pendidikan karakter dalam Pembelajaran Bahasa Indonesia Kelas XII. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode deskriptif  kualitatif. Pengumpulan data menggunakan metode dokumentasi dengan media kartu data. Analisis data dengan menggunakan  model  analisis kualitatif yang  yang memiliki tiga tahap: (a reduksi data, (b penyajian data, (c penarikan kesimpulan dan verifikasi. Hasil penelitian menunjukkan hal berikut. Pertama, novel Sutasoma karya Cok Sawitri memuat nilai- nilai pendidikan karakter yaitu religius, jujur, toleransi, disiplin, kerja keras, kreatif, mandiri, demokratis, rasa ingin tahu, semangat kebangsaan, cinta tanah air, menghargai prestasi, bersahabat atau komunikatif, peduli lingkungan, peduli sosial. Kedua novel Sutasoma terdiri dari struktur dalam dan luar. Struktur dalam atau unsur intrinsik, yaitu tema, alur, latar, penokohan serta sudut pandang. Adapun simpulan penelitian ini yaitu : (1 Novel Sutasoma memuat 17 nilai-nilai pendidikan karakter, (2 Struktur novel sutasoma terdiri dari struktur dalam dan struktur luar, (3 Proses kreatif pengarang dalam menciptakan novel yang terinspirasi dari karya Empu Tantular dengan judul resmi Parusadha yang populer dengan nama Sutasoma. Dalam kisah novel Sutasoma karya Cok Sawitri ternyata ditemukan pula proses ajaran Mahayan Tantra, yang mengungkapkan jalan rahasia yoga tantra, dan bagaimana seorang raja menerapkan dharma agama, dharma negara tanpa mempehitungkan kebhinekaan. Alur pada novel Sutasoma karya Cok Sawitri  dengan nilai -nilai pendidi kan karakter yang terdapat di dalamnya dapat memberikan inspirasi bagi pembaca. Hal ini berarti ada nilai-nilai positif yang dapat diambil dan direalisasikan oleh pembaca dalam kehidupan sehari-hari. Nilai pendidikan karakter dalam

  3. PENGARUH PRAKTIK KERJA INDUSTRI DAN LINGKUNGAN KELUARGA TERHADAP MOTIVASI BERWIRAUSAHA SISWA KELAS XII PEMASARAN SMK NEGERI 2 SEMARANG

    Directory of Open Access Journals (Sweden)

    Sodikin

    2014-06-01

    Full Text Available Motivasi siswa untuk menjadi seorang wirausaha dipengaruhi oleh praktik kerja industri dan lingkungan keluarga. Permasalahan penelitian ini adalah: sebesar besar pengaruh praktik kerja industri dan lingkungan keluarga terhadap motivasi berwirausaha siswa baik secara parsial maupun simultan. Populasi dalam penelitian ini berjumlah 99 siswa yang terdiri dari kelas XII Pemasaran SMK Negeri 2 Semarang, karena merupakan penelitian populasi sehingga semua populasi dijadikan sampel penelitian. Variabel yang diteliti yaitu variabel praktik kerja industri, lingkungan keluarga dan motivasi berwirausaha. Metode pengumpulan data menggunakan angket dan dokumentasi. Analisis data menggunakan analisis deskripsi persentase dan analisis regresi berganda. Hasil penelitian uji regresi menunjukkan hasil uji parsial untuk praktik kerja industri diperoleh thitung sebesar 4,847 dengan signifikansi 0,000 dan lingkungan keluarga diperoleh thitung sebesar 3,182 dengan signifikansi 0,002 berarti H0 ditolak dan Ha1, Ha2, Ha3 diterima. Besarnya pengaruh secara parsial untuk variabel praktik kerja industri sebesar 19,62% dan lingkungan keluarga sebesar 9,55%, secara simultan sebesar 44%. Student motivation to become an entrepreneur is influenced by industry work practices and family environment. The problems of this research are: the influence of industry work practices and family environment against entrepreneurial motivation either partially or simultaneously. The population in this study is composed of 99 students of class XII SMK N 2 Semarang Marketing, as a research population so that all the population made research sample. The variables studied were industry work practices, family environment and entrepreneurial motivation. Methods of data collection using questionnaire and documentation. Data analysis using descriptive analysis and multiple regression analysis percentage. Results of regression studies showed partial test results obtained for industrial work practices

  4. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

    Science.gov (United States)

    von Brühl, Marie-Luise; Stark, Konstantin; Steinhart, Alexander; Chandraratne, Sue; Konrad, Ildiko; Lorenz, Michael; Khandoga, Alexander; Tirniceriu, Anca; Coletti, Raffaele; Köllnberger, Maria; Byrne, Robert A.; Laitinen, Iina; Walch, Axel; Brill, Alexander; Pfeiler, Susanne; Manukyan, Davit; Braun, Siegmund; Lange, Philipp; Riegger, Julia; Ware, Jerry; Eckart, Annekathrin; Haidari, Selgai; Rudelius, Martina; Schulz, Christian; Echtler, Katrin; Brinkmann, Volker; Schwaiger, Markus; Preissner, Klaus T.; Wagner, Denisa D.; Mackman, Nigel; Engelmann, Bernd

    2012-01-01

    Deep vein thrombosis (DVT) is a major cause of cardiovascular death. The sequence of events that promote DVT remains obscure, largely as a result of the lack of an appropriate rodent model. We describe a novel mouse model of DVT which reproduces a frequent trigger and resembles the time course, histological features, and clinical presentation of DVT in humans. We demonstrate by intravital two-photon and epifluorescence microscopy that blood monocytes and neutrophils crawling along and adhering to the venous endothelium provide the initiating stimulus for DVT development. Using conditional mutants and bone marrow chimeras, we show that intravascular activation of the extrinsic pathway of coagulation via tissue factor (TF) derived from myeloid leukocytes causes the extensive intraluminal fibrin formation characteristic of DVT. We demonstrate that thrombus-resident neutrophils are indispensable for subsequent DVT propagation by binding factor XII (FXII) and by supporting its activation through the release of neutrophil extracellular traps (NETs). Correspondingly, neutropenia, genetic ablation of FXII, or disintegration of NETs each confers protection against DVT amplification. Platelets associate with innate immune cells via glycoprotein Ibα and contribute to DVT progression by promoting leukocyte recruitment and stimulating neutrophil-dependent coagulation. Hence, we identified a cross talk between monocytes, neutrophils, and platelets responsible for the initiation and amplification of DVT and for inducing its unique clinical features. PMID:22451716

  5. Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

    Science.gov (United States)

    Semeraro, Fabrizio; Ammollo, Concetta T.; Morrissey, James H.; Dale, George L.; Friese, Paul; Esmon, Naomi L.

    2011-01-01

    The release of histones from dying cells is associated with microvascular thrombosis and, because histones activate platelets, this could represent a possible pathogenic mechanism. In the present study, we assessed the influence of histones on the procoagulant potential of human platelets in platelet-rich plasma (PRP) and in purified systems. Histones dose-dependently enhanced thrombin generation in PRP in the absence of any trigger, as evaluated by calibrated automated thrombinography regardless of whether the contact phase was inhibited. Activation of coagulation required the presence of fully activatable platelets and was not ascribable to platelet tissue factor, whereas targeting polyphosphate with phosphatase reduced thrombin generation even when factor XII (FXII) was blocked or absent. In the presence of histones, purified polyphosphate was able to induce thrombin generation in plasma independently of FXII. In purified systems, histones induced platelet aggregation; P-selectin, phosphatidylserine, and FV/Va expression; and prothrombinase activity. Blocking platelet TLR2 and TLR4 with mAbs reduced the percentage of activated platelets and lowered the amount of thrombin generated in PRP. These data show that histone-activated platelets possess a procoagulant phenotype that drives plasma thrombin generation and suggest that TLR2 and TLR4 mediate the activation process. PMID:21673343

  6. Preliminary Investigations of The Bioarchaeology of Medieval Giecz (XI-XII C.: Examples of Trauma and Stress

    Directory of Open Access Journals (Sweden)

    Agnew Amanda M.

    2014-07-01

    Full Text Available Human skeletal remains from past populations are an invaluable source to objectively study biological history. The combined biological and cultural assessment of bioarchaeology offers a unique perspective on the adaptation of people to their environment. This study summarizes a portion of ongoing work to decipher trends related to health and lifestyle in early medieval (XI-XII c. Giecz, Poland. The skeletal assemblage from Giecz, the “Giecz Collection”, represents a community positioned at a major center of political, economic, and religious power during this important time in Polish history. Non-violent traumatic injuries were investigated to elucidate trends related to possible types and rigor of activities and linear femoral growth trends were analyzed to assess patterns of stress. Preliminary results suggest that all members of the community (men, women, and adolescents contributed to a lifestyle characterized by repetitive hard-work. Furthermore, it appears that most individuals suffered from health insults negatively affecting their development and perhaps their mortality.

  7. “The Testament” of XII Pandito Hambo-Lama Dashidorzhi Ithegelov in the Context of Buddhist Philosophy

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    Elizaveta E. Baldanmaksarova

    2017-12-01

    Full Text Available The article deals with a hitherto unexamined literary text written by a famous Buddhist philosopher and scientist XII Pandito Hambo-Lama Dashidorzhi Itigelov. This text is the last poem by D. Itigelov entitled “The Testament” (1927 written in the genre of the epistle and addressed to the people of the 21 st century. 2017 is a year of the 90th anniversary of the phenomenal state achieved by the philosopher; on September 10, Buryat people celebrate the 15th anniversary of his acquisition of the Precious Inexhaustible Body. Not only was D. Itigelov a leader of the Buryat society who headed its religious and secular (state activity until 1917, he also was an educated theologian and a gifted writer who left rich literary, religious, and philosophical heritage relevant in the context of the Buddhist aesthetics and philosophy. This essay calls for the necessity to make this heritage available to public by stressing its originality and relevance for contemporary society.

  8. Estrategias territoriales de un poder monástico en la Galicia medieval: Celanova (siglos X-XII

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    José Carlos SÁNCHEZ PARDO

    2011-02-01

    Full Text Available Se pretende afrontar un tema tradicional en la historiografía medieval española, como son los dominios monásticos, desde la perspectiva menos explorada de las estrategias espaciales que la reciente expansión del uso de los Sistemas de Información Geográfica ha facilitado. De esta manera, a través del caso gallego del monasterio de Celanova entre los siglos X y XII, observamos la complejidad que se esconde tras la planificación de la ubicación de uno de estos centros de poder así como la variedad y flexibilidad de tácticas empleadas en su proceso de crecimiento. Todo ello no solo enfatiza el conocido alto grado de conocimiento del entorno de los poderes señoriales entre finales de la Alta y Plena Edad Media, sino que también revela la importancia que dichos grupos daban a las estrategias espaciales en relación con la estructura preexistente de poblamiento y el papel que estas jugaron en el proceso de feudalización del noroeste peninsular.

  9. MOJAVE. XII. ACCELERATION AND COLLIMATION OF BLAZAR JETS ON PARSEC SCALES

    Energy Technology Data Exchange (ETDEWEB)

    Homan, D. C. [Department of Physics, Denison University, Granville, OH 43023 (United States); Lister, M. L.; Richards, J. L. [Department of Physics, Purdue University, 525 Northwestern Avenue, West Lafayette, IN 47907 (United States); Kovalev, Y. Y. [Astro Space Center of Lebedev Physical Institute, Profsoyuznaya 84/32, 117997 Moscow (Russian Federation); Pushkarev, A. B.; Savolainen, T.; Ros, E. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Kellermann, K. I., E-mail: homand@denison.edu [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States)

    2015-01-10

    We report on the acceleration properties of 329 features in 95 blazar jets from the MOJAVE Very Long Baseline Array program. Nearly half the features and three-quarters of the jets show significant changes in speed and/or direction. In general, apparent speed changes are distinctly larger than changes in direction, indicating that changes in the Lorentz factors of jet features dominate the observed speed changes rather than bends along the line of sight. Observed accelerations tend to increase the speed of features near the jet base, ≲ 10-20 pc projected, and decrease their speed at longer distances. The range of apparent speeds at a fixed distance in an individual jet can span a factor of a few, indicating that shock properties and geometry may influence the apparent motions; however, we suggest that the broad trend of jet features increasing their speed near the origin is due to an overall acceleration of the jet flow out to deprojected distances of the order of 10{sup 2} pc, beyond which the flow begins to decelerate or remains nearly constant in speed. We estimate intrinsic rates of change of the Lorentz factors in the galaxy frame of the order of Γ-dot /Γ≃10{sup −3} to 10{sup –2} yr{sup –1}, which can lead to total Lorentz factor changes of a factor of a few on the length scales observed here. Finally, we also find evidence for jet collimation at projected distances of ≲ 10 pc in the form of the non-radial motion and bending accelerations that tend to better align features with the inner jet.

  10. Esclavos musulmanes en los hospitales de cautivos de la Orden Militar de Santiago (siglos XII y XIII

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    Echevarría Arsuaga, Ana

    2007-12-01

    Full Text Available Military Orders had slave manpower in their lands since their foundation. However, the hospitals for ransoming captives owned by the Order of Santiago are the best example of how slavery worked in the kingdom of Leon-Castile during the twelfth and thirteenth centuries. These houses had enough room to provide lodging for captives while ransoms were being negotiated. They also helped to redistribute those Muslims who, lacking this possibility, became slaves of the order itself, or were sold in the slave markets of the kingdom. The scarce records kept in the Archivo Histórico Nacional, section Órdenes Militares, referring to slaves, help to understand the development of traffic, work and manumission of these people.

    Las órdenes militares dispusieron desde su fundación de mano de obra esclava en sus tierras, pero la institución que mejor sirve para estudiar la esclavitud en los siglos XII y XIII en los reinos de León y Castilla son los hospitales para la redención de cautivos de la Orden de Santiago. Estas instituciones disponían de espacio para alojar a los cautivos mientras se negociaban rescates con los poderes islámicos, y atendían a la redistribución de aquellos musulmanes que, por no haber sido redimidos, pasaban a ser esclavos de la propia orden o a ser vendidos en los mercados de los reinos cristianos. Los escasos documentos de la sección de Órdenes Militares del Archivo Histórico Nacional dedicados a esclavos ayudan a comprender el funcionamiento del tráfico, trabajo y liberación de este colectivo.

  11. PENERAPAN SIMASET PADA MATERI LAPORAN PENERIMAAN DAN PENDISTRIBUSIAN SARANA DAN PRASARANA UNTUK MENINGKATKAN MOTIVASI BELAJAR SISWA KELAS XII ADMINISTRASI PERKANTORAN SMKN 1 MALANG

    Directory of Open Access Journals (Sweden)

    Novi Damayanti

    2017-11-01

    Full Text Available XII APK 1 class at SMKN 1 Malang have a problem on their learning motivation that showed by their attitude at the time of learning. The student’s motivation is relatively low. It is because the material, which is the report of facilities and infrastructure reception and distribution, requires a high concentration, therefore they need SIMAset as learning media that can help them to reach the goal of learning. The purpose of this research is to increase student’s motivation. This research is Classroom Action Research (CAR that was conducted in two cycles in which each cycle consist of planning, implementation, observation, and reflection. Data collection techniques in this study was done by using observation, interview, test, documentation, and questionnaire. This research using qualitative interactive techniques data analysis. The result of this study showed that SIMAset can increase student motivation. Abstrak: Kelas XII APK 1 SMKN 1 Malang memiliki permasalahan pada motivasi belajar yang ditunjukkan oleh sikap siswa pada saat proses pembelajaran berlangsung. Motivasi belajar siswa kelas XII APK 1 SMKN 1 Malang relatif rendah. Hal tersebut disebabkan karena materi yang dipelajari yaitu laporan penerimaan dan pendistribusian sarana dan prasarana membutuhkan konsentrasi yang tinggi, sehingga dibutuhkan media pembelajaran SIMAset yang dapat membantu siswa untuk mencapai tujuan pembelajaran dengan baik. Penelitian ini bertujuan untuk meningkatkan motivasi belajar siswa. Penelitian ini merupakan Penelitian Tindakan Kelas (PTK yang dilaksanakan dalam dua siklus, masing-masing siklus terdiri atas tahap perencanaan, pelaksanaan, pengamatan, dan refleksi. Teknik pengumpulan data yang digunakan yaitu observasi, wawancara, tes, dokumentasi, dan angket. Analisis data menggunakan teknik analisis data kualitatif interaktif. Hasil penelitian menunjukkan bahwa SIMAset dapat meningkatkan motivasi belajar siswa.

  12. Energy Levels and Radiative Rates for Transitions in F-like Sc XIII and Ne-like Sc XII and Y XXX

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    Kanti M. Aggarwal

    2018-05-01

    Full Text Available Energy levels, radiative rates and lifetimes are reported for F-like Sc XIII and Ne-like Sc XII and Y XXX for which the general-purpose relativistic atomic structure package (GRASP has been adopted. For all three ions, limited data exist in the literature but comparisons have been made wherever possible to assess the accuracy of the calculations. In the present work, the lowest 102, 125 and 139 levels have been considered for the respective ions. Additionally, calculations have also been performed with the flexible atomic code (FAC to (particularly confirm the accuracy of energy levels.

  13. Energy Levels and Radiative Rates for Transitions in F-like Sc XIII and Ne-like Sc XII and Y XXX

    Science.gov (United States)

    Aggarwal, Kanti

    2018-05-01

    Energy levels, radiative rates and lifetimes are reported for F-like Sc~XIII and Ne-like Sc~XII and Y~XXX for which the general-purpose relativistic atomic structure package ({\\sc grasp}) has been adopted. For all three ions limited data exist in the literature but comparisons have been made wherever possible to assess the accuracy of the calculations. In the present work the lowest 102, 125 and 139 levels have been considered for the respective ions. Additionally, calculations have also been performed with the flexible atomic code ({\\sc fac}) to (particularly) confirm the accuracy of energy levels.

  14. En busca de una frontera entre Galicia y Portugal: Las tierras miñotas en los siglos XI-XII

    OpenAIRE

    Flórez Díaz, Javier

    2017-01-01

    RESUMEN: Con la realización de esta investigación trato de abordar cómo y cuándo se crea la frontera galaico-portuguesa. Y si es una creación ex novo y propia de la coyuntura peninsular; o bien refleja un pasado romano, suevo-visigodo y altomedieval hasta la propia formación de un nuevo Reino independiente: Portugal, en el siglo XII. Para ello, utilizaré fundamentalmente la documentación diocesana de la región (Orense, Tuy y Braga), la documentación de la cancillería regia portuguesa...

  15. Japanese contributions to IAEA INTOR workshop, phase two A, part 2, chapter XI: concept evolution, chapter XII: design concept, and chapter XIII: operation and test programme

    International Nuclear Information System (INIS)

    Tomabechi, Ken; Fujisawa, Noboru; Iida, Hiromasa

    1985-07-01

    This report corresponds to Chapters XI, XII, and XIII of Japanese contribution report to IAEA INTOR Workship, Phase Two A, Part 2. In the phase Two A, Part 2 workshop, we have studied critical technical issues and have also assessed scientific and technical data bases. Based on those results, the INTOR design have been modified to upgrade the design concept. The major modification items are related to plasma beta value, plasma operation scenario, reactor size reduction, neutron fluence, tritium producing blanket, and implementation of active control coils. In those chapters, the concept evolution for the design modification and main results are described. (author)

  16. Hegel y Aristóteles: Una lectura de Metafísica XII, 7,1072b 18-30

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    Luis Xavier López-Farjeat

    2013-11-01

    Full Text Available The author does a hegelian interpretation of Metaphysics XII, 7, 1072b 18-30, passage with which the Encyclopedia of the Philosophical Sciences concludes. Here are drawn the relations and similitudes that exist between Aristotle's Unmoved Mover and Hegel's Absolute. In order to understand in which points both thinkers coincide when describing divine thought, it is highly important to analyze the notions of thought, movement, power, act, concept, object, material substance, formal substance and suprasensible substance. The interpretative turn that Hegel does of Metaphysics and the comparative reading here offered, point towards a better understanding of the nature of the Unmoved Mover and the Absolute.

  17. Efecto de un Programa de Capacitación sobre el Clima Organizacional en la Zona Registral N° XII. Arequipa, 2016

    OpenAIRE

    Herrera Florez, Marcela

    2017-01-01

    La presente investigación tiene como finalidad realizar el estudio del estado en que se encuentra el clima organizacional en la Zona Registral N° XII; Sede Arequipa, capacitar al personal en temas relacionados con la mejora del clima organizacional y evaluar a los trabajadores luego de las capacitaciones impartidas. La hipótesis a comprobarse fue: es probable que el programa de capacitación “Desarrollo de Competencias de Dirección” mejorará el clima organizacional en los trabajadores de la...

  18. Medicinal Flowers. XXXII. Structures of oleanane-type triterpene saponins, perennisosides VIII, IX, X, XI, and XII, from the flowers of Bellis perennis.

    Science.gov (United States)

    Morikawa, Toshio; Li, Xuezheng; Nishida, Eriko; Nakamura, Seikou; Ninomiya, Kiyofumi; Matsuda, Hisashi; Hamao, Makoto; Muraoka, Osamu; Hayakawa, Takao; Yoshikawa, Masayuki

    2011-01-01

    Five new triterpene saponins perennisosides VIII (1), IX (2), X (3), XI (4), and XII (5) were isolated from the MeOH-eluated fraction of the methanolic extract from the flowers of Bellis perennis. The MeOH-eluted fraction of the methanolic extract from the flowers of B. perennis was found to inhibit gastric emptying in olive oil-loaded mice at a dose of 200 mg/kg, per os (p.o.). The stereostructures of 1-5 were elucidated on the basis of chemical and spectroscopic evidence.

  19. FOREWORD: The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) (Pine Mountain, Georgia, USA, 19-23 April 2009) The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) (Pine Mountain, Georgia, USA, 19-23 April 2009)

    Science.gov (United States)

    Orlando, Thomas M.; Diebold, Ulrike

    2010-03-01

    The 12th International Workshop on Desorption Induced by Electronic Transitions (DIET XII) took place from 19-23 April 2009 in Pine Mountain, Georgia, USA. This was the 12th conference in a strong and vibrant series, which dates back to the early 1980s. DIET XII continued the tradition of exceptional interdisciplinary science and focused on the study of desorption and dynamics induced by electronic excitations of surfaces and interfaces. The format involved invited lectures, contributed talks and a poster session on the most recent developments and advances in this area of surface physics. The Workshop International Steering Committee and attendees wish to dedicate DIET XII to the memory of the late Professor Theodore (Ted) Madey. Ted was one of the main pioneers of this field and was one of the primary individuals working to keep this area of science exciting and adventurous. His overall contributions to surface science were countless and his contributions to the DIET field and community were enormous. He is missed and remembered by many friends and colleagues throughout the world. The papers collected in this issue cover many of the highlights of DIET XII. Topics include ultrafast electron transfer at surfaces and interfaces, quantum and spatially resolved mapping of surface dynamics and desorption, photon-, electron- and ion-beam induced processes at complex interfaces, the role of non-thermal desorption in astrochemistry and astrophysics and laser-/ion-based methods of examining soft matter and biological media. Although the workshop attracted many scientists active in the general area of non-thermal surface processes, DIET XII also attracted many younger scientists (i.e., postdoctoral fellows, advanced graduate students, and a select number of advanced undergraduate students). This field has had an impact in a number of areas including nanoscience, device physics, astrophysics, and now biophysics. We believe that this special issue of Journal of Physics

  20. A domus infirmorum do mosteiro de Santa Cruz de Coimbra e o acolhimento no hospital São Nicolau (Portugal, séculos XII-XIII

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    Dulce O. Amarante dos Santos

    2015-06-01

    Full Text Available Este artigo configura os primeiros resultados de uma pesquisa de micro-história sobre dois espaços de saúde e practica médica no Mosteiro agostiniano de Santa Cruz de Coimbra, a saber, a enfermaria ou domus infirmorume o Hospital São Nicolau. O primeiro, construído no século XII, constituiu-se na área do mosteiro crúzio destinada ao cuidado com os monges doentes, definido primeiro nas regras de fundação e depois presente nos Costumeiros ou Liberordinis posteriores. O Hospital São Nicolau foi igualmente fundado em meados do século XII e funcionou como os outros hospitais de caridade medieval, ou seja, hospedava peregrinos, albergava pobres, tratava dos doentes e acolhia desvalidos. Esses dois espaços favoreceram os estudos médicos, como atestam os títulos da biblioteca, ao mesmo tempo foram lócus de experimentação das medidas preventivas e de práticas terapêuticas.

  1. PEMANFAATAN FACEBOOK DALAM KETERAMPILAN MEMPRODUKSI TEKS CERITA SEJARAH PADA SISWA KELAS XII IPS-1 SMA NEGERI 3 BOJONEGORO TAHUN PELAJARAN 2015/2016

    Directory of Open Access Journals (Sweden)

    Susanto Susanto

    2015-12-01

    Full Text Available Facebook already familiar among students, thus giving rise to problems in the form of formulation of the problem. How harness, effectiveness studies, and student learning outcomes associated with social media media (facebook in improving the learning skills to produce historical narrative text in class XII IPS 1SMAN 3 Bojonegoro academic year 2015/2016? The method in use is the method of data collection in the form of questionnaires and interviews, and observations during the study (good attitude, knowledge and skills. Results of the research in this paper indicate that Facebook utilize media based learning as e-learning will be developed along technology. The learned very look fabulous. Students of class XII IPS -1 amounted to 32 students. Students who scored above 79 to as many as 27 students or equal to 84.4%. This means that students experiencing learning completeness. While students who scored below 79 or 78 down as much as 5 students, equivalent to 15.6%. Means there are five students who did not complete the work TCS.Saran in this study should be a teacher, the use of FB as a learning medium based e-learning, especially in order to improve the achievement of learning outcomes.

  2. Franklin Roosevelt, Pius XII, Joseph Stalin and the Problem of the USSR’s Image and Reputation During the Second World War

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    Filippov Boris

    2016-08-01

    Full Text Available The aggression of Hitler’s Germany against the USSR made our country an ally of the United States and Great Britain. But the decision to help USSR with weapons and hardware (the lend-lease act faced opposition not only from the American isolationists but also from religious groups. Both Catholics and Protestants were against the very idea of helping the country in which churches were destroyed and the faithful were persecuted. They have considered such an idea to be immoral. To overcome the opposition in Congress, president F. D. Roosevelt and the US diplomats tried to convince Stalin to reject his policies of religious oppression. Roosevelt also asked pope Plus XII for help. At the same time German and Italian ambassadors were trying to convince the Pope to support their “crusade against the godless Bolshevik Russia”. The question of USSR’s image was an important issue throughout the course of war. The article tells the history of the most signifi cant efforts undertaken by the Western allies and Stalin to improve the international reputation of the USSR. First of all, it tells the story of the mysterious letter from Stalin to Plus XII (1942 and about even more mysterious visit of the American priest Stanislav Orlemansky to Moscow and his meeting with Stalin in 1944.

  3. National Library of Norway's new database of 22 manuscript maps concerning the Swedish King Charles XII's campaign in Norway in 1716 and 1718

    Directory of Open Access Journals (Sweden)

    Benedicte Gamborg Brisa

    2003-03-01

    Full Text Available The National Library of Norway is planning to digitise approximately 1,500 manuscript maps. Two years ago we started working on a pilot project, and for this purpose we chose 22 maps small enough to be photographed in one piece. We made slides 6 x 7 cm in size, converted the slides into PhotoCDs and used four different resolutions on JPEG-files. To avoid large file sizes, we had to divide the version with the biggest resolution into four pieces. The preliminary work was done in Photoshop, the database on the web is made in Oracle. You can click on the map to zoom. Norwegians and probably Swedes during the Great Northern War drew the 22 maps when the Swedish King Charles XII in 1716 and 1718 unsuccessfully attempted to conquer Norway. The database is now accessible on the National Library of Norway's web site. The database is in Norwegian, but we are working on an English version as well. The maps are searchable on different topics, countries, counties, geographical names, shelfmarks or a combination of these. We are planning to expand the database to other manuscript maps later. This is the reason why it is possible to search for obvious subjects as Charles XII and the Great Northern War.

  4. STUDI KOMPARASI SELF CONTROL SISWA YANG MEMILIKI KECERDASAN SPIRITUAL TINGGI DAN RENDAH DI KELAS XII SMAN I KOTA KEDIRI TAHUN PELAJARAN 2013/2014

    Directory of Open Access Journals (Sweden)

    Ady Alfan Mahmudinata

    2016-07-01

    Full Text Available Referring to the character of the Education Act in Indonesia listed in Act 20 of 2003 on National Education System Indonesia Article: 1 The purpose of national education to develop the potential of learners to have the intelligence, personality, and noble character; and article 3, paragraph 1: National education serves to develop the ability and shape the character and civilization of the nation's dignity in the context of national life as well as you view the proyeksitas Islamic religious education that is feeding religious spiritual student-related non- Islamic values are synergistic against strong self control gaining control himself strong for the students, for the writer interested to learn and find out about the intelligence level of spiritual and differences self Control students, among students who have spiritual intelligence of high and low class XII SMAN I Kediri, with the formulation of the problem 1 What is the level of intelligence spiritual students ? 2 How Self Control students who have high spiritual intelligence? 3 How Self Control students who have low spiritual intelligence? 4 Do Self Control students who have high spiritual intelligence is stronger than the Self Control students who have low spiritual intelligence?This study uses a mixed method approach. The data collection was conducted by questionnaire, documentation, interviews and observation. The population of this research is class XII student of SMAN I Kediri. Sampling starts with random sampling techniques on Muslim students in class XII and generalized according to the level of intelligence Spiritual owned. Statistical data analysis with independent t-test formula. The research sample for the group of students who have Spiritual intelligence is as many as 152 students were taken based on Table Krejcie for error rate ( of 0.05 of the total students totaling 250 students, from 152 students after given a rating based on spiritual intelligence instrument  then found the

  5. Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.

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    Charles E Bane

    Full Text Available Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP suggested that the protease factor XIa contributed to disseminated intravascular coagulation (DIC and to the cytokine response during sepsis. We investigated the importance of factor XI to cytokine and coagulation responses during the first 24 hours after CLP. Compared to wild type littermates, factor XI-deficient (FXI-/- mice had a survival advantage after CLP, with smaller increases in plasma levels of TNF-α and IL-10 and delayed IL-1β and IL-6 responses. Plasma levels of serum amyloid P, an acute phase protein, were increased in wild type mice 24 hours post-CLP, but not in FXI-/- mice, supporting the impression of a reduced inflammatory response in the absence of factor XI. Surprisingly, there was little evidence of DIC in mice of either genotype. Plasma levels of the contact factors factor XII and prekallikrein were reduced in WT mice after CLP, consistent with induction of contact activation. However, factor XII and PK levels were not reduced in FXI-/- animals, indicating factor XI deficiency blunted contact activation. Intravenous infusion of polyphosphate into WT mice also induced changes in factor XII, but had much less effect in FXI deficient mice. In vitro analysis revealed that factor XIa activates factor XII, and that this reaction is enhanced by polyanions such polyphosphate and nucleic acids. These data suggest that factor XI deficiency confers a survival advantage in the CLP sepsis model by altering the cytokine response to infection and blunting activation of the contact (kallikrein-kinin system. The findings support the hypothesis that factor XI functions as a bidirectional interface between contact activation and thrombin generation, allowing the two processes to influence each other.

  6. XII Recontres De Blois

    Science.gov (United States)

    Kaluzienski, Louis (Technical Monitor); Forman, William

    2004-01-01

    In the initial awarding of the grant, we had difficulty phasing our proposed support of graduate students, postdoctoral fellows and young US scientists with the meeting schedule and the grant cycle. Initially, the grant arrived too late to support the meeting. The following year, a combination of the renewal process and the meeting announcement prevented us from announcing the support opportunity sufficiently in advance to allow us to make awards and provide support. As described in the initial proposal, the Moriond and Blois meetings are a unique opportunity for younger researchers to make oral presentations of their work at an international venue. As noted above, the phasing of meetings combined with the difficulty of arranging foreign travel for scientists at other institutions precluded the possibility of supporting the proposed meetings and providing young US scientists and post-doctoral fellows support to attend these meetings.

  7. Exophytic pilocytic astrocytoma of the brain stem in an adult with encasement of the caudal cranial nerve complex (IX-XII): presurgical anatomical neuroimaging using MRI

    Energy Technology Data Exchange (ETDEWEB)

    Yousry, Indra; Yousry, Tarek A. [Department of Neuroradiology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistr. 15, 81377, Munich (Germany); Muacevic, Alexander; Olteanu-Nerbe, Vlad [Department of Neurosurgery, Klinikum Grosshadern, Ludwig-Maximilians University, Munich (Germany); Naidich, Thomas P. [Department of Radiology, Section of Neuroradiology, Mount Sinai Hospital, New York (United States)

    2004-07-01

    We describe a rare case of adult pilocytic astrocytoma in which exophytic growth from the brain stem presented as a right cerebellopontine angle mass. An initial MRI examination using T2- and T1-weighted images without and with contrast suggested the diagnosis of schwannoma. Subsequent use of 3D CISS (three-dimensional constructive interference in steady state) and T1-weighted contrast-enhanced 3D MP-RAGE (three-dimensional magnetization prepared rapid acquisition gradient echo) sequences led to the diagnosis of an exophytic brain stem tumor, documented the precise relationships of the tumor to cranial nerve VIII, revealed encasement of cranial nerves IX-XII (later confirmed intraoperatively), and provided the proper basis for planning surgical management. (orig.)

  8. Pengaruh Kompetensi Pedagogik dan Kompetensi Profesional Guru terhadap Economic Literacy melalui Prestasi Belajar Siswa Kelas XII IPS di SMA Kota Malang

    Directory of Open Access Journals (Sweden)

    Denik Wulandari

    2013-10-01

    Full Text Available Tujuan penelitian ini untuk menguji pengaruh (1 kompetensi pedagogik guru terhadap economic literacy melalui prestasi belajar siswa, (2 kompetensi profesional guru terhadap economic literacy melalui prestasi belajar siswa. Penelitian dilakukan terhadap siswa kelas XII IPS di SMA RSBI se-Kota Malang pada tahun 2012, data diperoleh dari angket, tes, dan dokumentasi. Hasil pene-litian: (1 kompetensi pedagogik guru berpengaruh positif signifikan terhadap economic literacy; (2 kompetensi pedagogik guru berpengaruh positif signifikan terhadap prestasi belajar; (3 prestasi belajar berpengaruh positif signifikan terhadap economic literacy; (4 kompetensi profesional guru berpengaruh positif signifikan terhadap economic literacy; dan (5 kompetensi profesional guru berpengaruh positif signifikan terhadap prestasi belajar. Berdasarkan hasil penelitian tersebut secara keseluruhan dapat diketahui bahwa kompetensi pedagogik dan kompetensi profesional guru dapat mempengaruhi economic literacy siswa melalui prestasi belajar siswa. Kata kunci: kompetensi pedagogik, kompetensi profesional, prestasi belajar, economic literacy

  9. Uma pequena igreja, um grande almofariz cultural: iconografia céltica religiosa em Kilpeck, Inglaterra, século XII

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    Elisabete Leal

    2015-10-01

    Full Text Available Este artigo discorre sobre alguns aspectos iconográficos presentes nas mísulas da igreja de St. Mary e St. David de Kilpeck, Herefordshire, Inglaterra, construída no século XII. Destacamos a presença de elementos que denunciam um forte hibridismo cultural entre o cristianismo e antigos símbolos religiosos, considerados, no mesmo contexto da construção, como símbolos pagãos e profanos. Desta forma, pretendemos salientar a complexidade dos processos culturais durante a Idade Média, e os fenômenos de circularidade cultural que atuam fortemente neste período e que podemos analisar através da cultura visual. Levaremos em consideração a localização da igreja em uma região de fronteira, para uma compreensão mais profunda dos elementos encontrados.

  10. The Joint International Conference of the XII International Conference on Mechanisms and Mechanical Transmissions (MTM) and the XXIII International Conference on Robotics (Robotics ’16)

    CERN Document Server

    Lovasz, Erwin-Christian; Hüsing, Mathias; Maniu, Inocentiu; Gruescu, Corina

    2017-01-01

    This volume presents the proceedings of the Joint International Conference of the XII International Conference on Mechanisms and Mechanical Transmissions (MTM) and the XXIII International Conference on Robotics (Robotics ’16), that was held in Aachen, Germany, October 26th-27th, 2016. It contains applications of mechanisms and transmissions in several modern technical fields such as mechatronics, biomechanics, machines, micromachines, robotics and apparatus. In connection with these fields, the work combines the theoretical results with experimental testing. The book presents reviewed papers developed by researchers specialized in mechanisms analysis and synthesis, dynamics of mechanisms and machines, mechanical transmissions, biomechanics, precision mechanics, mechatronics, micromechanisms and microactuators, computational and experimental methods, CAD in mechanism and machine design, mechanical design of robot architecture, parallel robots, mobile robots, micro and nano robots, sensors and actuators in ro...

  11. Exophytic pilocytic astrocytoma of the brain stem in an adult with encasement of the caudal cranial nerve complex (IX-XII): presurgical anatomical neuroimaging using MRI

    International Nuclear Information System (INIS)

    Yousry, Indra; Yousry, Tarek A.; Muacevic, Alexander; Olteanu-Nerbe, Vlad; Naidich, Thomas P.

    2004-01-01

    We describe a rare case of adult pilocytic astrocytoma in which exophytic growth from the brain stem presented as a right cerebellopontine angle mass. An initial MRI examination using T2- and T1-weighted images without and with contrast suggested the diagnosis of schwannoma. Subsequent use of 3D CISS (three-dimensional constructive interference in steady state) and T1-weighted contrast-enhanced 3D MP-RAGE (three-dimensional magnetization prepared rapid acquisition gradient echo) sequences led to the diagnosis of an exophytic brain stem tumor, documented the precise relationships of the tumor to cranial nerve VIII, revealed encasement of cranial nerves IX-XII (later confirmed intraoperatively), and provided the proper basis for planning surgical management. (orig.)

  12. CT-clinical approach to patients with symptoms related to the V, VII, IX-XII cranial nerves and cervical sympathetics

    International Nuclear Information System (INIS)

    Kalovidouris, A.; Mancuso, A.A.; Dillon, W.

    1984-01-01

    Forty-three patients who had signs and symptoms possibly related to the extracranial course of cranial nerves V, VII, IX, X-XII, and the cervical sympathetics were examined prospectively using high resolution CT to obtain images of thin sections during rapid drip infusion of contrast material. Anatomic areas in the scan protocols included the posterior fossa, cavernous and paranasal sinuses, skull base, temporal bone, nasopharynx, parotid gland, tongue base, and neck. Nine of the 23 patients with possible fifth nerve deficits had extracranial structural lesions that explained the symptoms; none of these nine, however, had typical trigeminal neuralgia. Of eight patients with peripheral seventh nerve abnormalities, two had positive findings on scans. Of five patients presenting with referred ear pain, three had carcinoma of the upper aerodigestive tract. The authors' experience suggests that patients at high risk for structural lesions responsible for cranial nerve deficits can be selected by clinical criteria. Protocols for each clinical setting are presented

  13. Pesca y trabajo en el reino de Toledo. La cuenca alta y media del Tajo en los siglos XII al XVI

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    Sánchez Quiñones, Julián

    2006-06-01

    Full Text Available

    This work treats about the professions related with the fishing in the Kingdom of Toledo, in the high and middle course of river Tagus, from XII-XVIth centuries. Along these pages we have seen many different kind of people, public servants, great merchants, workers of the fisheries, involved in the fishing, trading and delivering of fish in this time. So with this article, we break with the idea which identified the fishing only with fishing men and boats showing how the medieval society was interested in every economic activity which produced profits.



    Este trabajo trata acerca de las profesiones relacionadas con la pesca en el Reino de Toledo, en la cuenca alta y media del río Tajo, de los siglos XII al XVI. A lo largo de estas páginas hemos visto muchos tipos diferentes de personas, oficiales públicos, grandes mercaderes, trabajadores de las pesquerías, envueltos en la captura, comercio y distribución del pescado. Con este artículo, queremos romper con la idea que identifica la pesca sólo con los pescadores y los barcos, mostrando como la sociedad medieval se interesaba en cualquier actividad económica que produjese beneficios.

  14. PENGARUH PELAKSANAAN OJT (ON THE JOB TRAINING DAN PERAN ORANGTUA TERHADAP MINAT BERWIRAUSAHA PADA SISWA KELAS XII KOMPETENSI KEAHLIAN AKUNTANSI DI SMK NEGERI 2 SEMARANG TAHUN AJARAN 2013/2014

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    Siti Mutmainah

    2013-11-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui pengaruh OJT (On The Job Training dan peran orangtua terhadap minat berwirausaha pada siswa kelas XII Kompetensi Keahlian Akuntansi di SMK Negeri 2 Semarang tahun ajaran 2013/2014. Populasi dalam penelitian adalah seluruh siswa kelas XII kompetensi keahlian akuntansi SMK Negeri 2 Semarang sebanyak 108 siswa dan sampel dalam penelitian adalah seluruh populasi yang berjumlah 108 siswa. Metode pengump ulan data yang digunakan adalah metode kuesioner. Metode analisis data yang digunakan yaitu analisis deskriptif dan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa ada pengaruh positif antara OJT dan peran orangtua terhadap minat berwi rausaha. Hasil penelitian diperoleh persamaan regresi linier berganda yaitu Y = 27,396+0,233X 1+0,892X2 +e. Kontribusi OJT dan peran orangtua terhadap minat berwirausaha secara silmutan sebesar 29,8%. Besarnya pengaruh secara parsial variabel OJT sebesar 4,54% dan besarnya pengaruh secara parsial variabel peran orangtua sebesar 16,08%. Berdasarkan hasil penelitian disimpulkan bahwa ada pengaruh OJT dan peran orangtua terhadap minat berwirausaha siswa kelas XII kompetensi keahlian akuntansi SMK Negeri 2 Semara ng tahun ajaran 2013/2014 baik secara simultan maupun parsial. This research has purpose for knowing effect of OJT (On The Job Training and parent’s fungtion toward interesting in entrepreneurship simultaneously and partially students class XII accounting skills competence in Vocational High School State 2 Semarang year 2013/2014. The population of this research is all students class XII accounting skills comp etence in Vocational High School State 2 Semarang as many as 108 students and sample of this research is all of population as many as 108 students. Data collection method was used a questionnaire method. Data collection method was used a questionnaire method. Method of data analysis is descriptive analysis and multiple regression analysis. The

  15. The constructive process in the Cimorro zone in the the Cathedral of Avila, (century XII-XIV. Hypothesis and its verification through the analysis of Structural Stability Smart and Sustainable Offices (SSO

    Directory of Open Access Journals (Sweden)

    Mª A. Benito Pradillo

    2018-01-01

    Full Text Available This paper presents a hypothesis about the order in the constructive process for the head zone in the Cathedral of Ávila, called Cimorro. The hypothesis proposed in this area considers for its construction three different stages: XII Century, XIII Century and XIV Century. The proposed hypotesis have been verified with the Analysis of Stability realised. The theoretical Framework used is the Limit Analysis to Masonry Structures. After prooving the Structural Stability for each of the building stages, the following conclusions are made: Through the XII Century, the possibility of closing the central vault without Buttress System for a short period of time and the subsequent placement of a tribune is stated. A fortification formed by the barbican and the «adarves» were built during the XIII Century. In the XIV Century, the tribune is removed and replaced with the Buttress System with buttress and double flying buttress, which we can see nowadays.

  16. PENGARUH HASIL BELAJAR MATA PELAJARAN PRODUKTIF AKUNTANSI, PROGRAM PRAKTIK KERJA INDUSTRI DAN SELF EFFICACY TERHADAP KESIAPAN KERJA SISWA KELAS XII PROGRAM KEAHLIAN AKUNTANSI DI SMK NEGERI 1 KENDAL TAHUN AJARAN 2013/2014

    Directory of Open Access Journals (Sweden)

    Noviana Noviana

    2013-02-01

    Full Text Available Sekolah Menengah Kejuruan merupakan lembaga pendidikan yang menghasilkan lulusan untuk siap kerja sesuai dengan bidang keahliannya. Kondisi di SMK Negeri 1 Kendal Tahun Ajaran 2012/2013 terdapat 66,67% atau 34 siswa yang bekerja diluar bidang akuntansi. Tujuan penelitian ini untuk mengetahui pengaruh hasil belajar mata pelajaran produktif akuntansi, program praktik kerja industri, dan self efficacy terhadap kesiapan kerja siswa kelas XII program keahlian akuntansi di SMK Negeri 1 Kendal Tahun Ajaran 2013/2014 baik secara parsial maupun simultan. Jenis penelitian ini adalah uji pengaruh dengan pendekatan kuantitatif. Populasi penelitian ini adalah seluruh siswa kelas XII program keahlian akuntansi sejumlah 105 siswa. Metode pengumpulan data menggunakan metode dokumentasi dan metode angket/kuesioner. Metode analisis data menggunakan analisis deskriptif, analisis regresi berganda, uji koefisien determinasi (R2, uji simultan (F, dan uji parameter individual (t. Hasil penelitian ini adalah secara parsial ada pengaruh hasil belajar mata pelajaran produktif akuntansi sebesar 25,70%, program praktik kerja industri sebesar 23,20%, dan self efficacy sebesar 32,90% terhadap kesiapan kerja siswa kelas XII. Sedangkan secara simultan ada pengaruh hasil belajar mata pelajaran produktif akuntansi, program praktik kerja industri, dan self efficacy terhadap kesiapan kerja siswa kelas XII program keahlian akuntansi di SMK Negeri 1 Kendal Tahun Ajaran 2013/2014 sebesar 43,10%. Vocational High School is an educational institution that produces graduates ready to work according to their expertise. Conditions at SMK Negeri 1 Kendal Academic Year 2012/2013 there are 66.67 % or 34 students working beyond the field of accounting The purpose of this study was to determine the effect of the learning outcomes of productive subjects accounting, on the job training program, and self-efficacy on job readiness class XII students accounting skills program at SMK Negeri 1 Kendal

  17. PENGARUH PERSEPSI SISWA TENTANG KOMPETENSI KEJURUAN, PENGUASAAN SOFT SKILL, DAN KEMATANGAN KARIR TERHADAP KESIAPAN KERJA SISWA KELAS XII AKUNTANSI SMK NEGERI 2 MAGELANG TAHUN AJARAN 2014/2015

    Directory of Open Access Journals (Sweden)

    Riska Afriani

    2015-06-01

    Full Text Available Berdasarkan observasi awal, diketahui bahwa belum semua siswa kelas XII Akuntansi mempunyai kesiapan kerja tinggi. Hal ini terlihat pada keterserapan lulusan pada tahun 2014 hanya sebesar 54% dari keseluruhan lulusan. Penelitian ini bertujuan untuk mengetahui adakah pengaruh persepsi siswa tentang kompetensi kejuruan, penguasaan soft skill, dan kematangan karir terhadap kesiapan kerja. Populasi penelitian ini adalah siswa kelas XII Akuntansi SMK Negeri 2 Magelang tahun ajaran 2014/2015. Berdasarkan rumus Isaac dan Michael, sampel sebanyak 84 siswa diambil sampel per kelas menggunakan teknik proportional random sampling.Metode pengumpulan data menggunakan angket. metode analisis data yang digunakan adalah analisis deskriptif dan analisis regresi berganda. Analisis deskriptif diperoleh bahwa kesiapan kerja siswa dalam kategori Siap, Persepsi Siswa tentang Kompetensi Kejuruan dalam kategori Baik, Penguasaan Soft Skill dalam kategori Baik, dan Kematangan Karir dalam kategori Matang. Hasil penelitian ini secara statistik menunjukkan bahwa terdapat pengaruh persepsi siswa tentang kompetensi kejuruan terhadap kesiapan kerja sebesar 19,9%, penguasaan soft skill terhadap kesiapan kerja sebesar 5,8%, dan kematangan karir terhadap kesiapan kerja sebesar 9,8%. Berdasarkan hasil penelitian di atas, dapat disimpulkan bahwa persepsi siswa tentang kompetensi kejuruan, penguasaan soft skill, dan kematangan karirberpengaruh terhadap kesiapan kerja. Saran yang diberikan, untuk meningkatkan kesiapan kerja siswa, hendaknya siswa diberikan pemahaman yang baik tentang kompetensi akuntansi, pelatihan soft skill, dan bimbingan karir. Based on initial observation, known that not all student on twelfth grade accounting have a high work readiness. This is shown by graduate occupancy to work in 2014 just 54% of all. The purpose of this research are to see the influence of Students Perception about Vocational Competency, Soft Skill Capability and Career Maturity toward Work

  18. La recepción del derecho justinianeo en España en la Baja Edad Media (siglos XII-XV). Un capítulo en la historia del derecho europeo

    OpenAIRE

    Torrent Ruiz, Armando José

    2013-01-01

    La recepción del derecho justinianeo en España o, si se prefiere, la recepción del ius commune en España durante los s. XII-XV, es un capítulo más de los fundamentos del derecho europeo dentro de una historia del derecho que hoy ya no debe ser una historia de los derechos nacionales sino historia del derecho europeo

  19. EFEKTIVITAS METODE DRILL BERBANTUAN MODUL PEMBELAJARAN DALAM UPAYA MENINGKATKAN HASIL BELAJAR SISWA KOMPETENSI DASAR JURNAL KHUSUS PERUSAHAAN DAGANG PADA SISWA KELAS XII IPS SMA NEGERI 10 SEMARANG TAHUN AJARAN 2013/2014

    Directory of Open Access Journals (Sweden)

    Meta Aditya Handayani

    2013-11-01

    Full Text Available Tujuan penelitian untuk mengetahui penerapan metode drill berbantuan modul dapat meningkatkan hasil belajar akuntansi kompetensi dasar Jurnal Khusus kelas XII IPS SMA Negeri 10 Semarang tahun ajaran 2013/2014 . Penelitian ini menggunakan metode quasi eksperimen. Populasi dalam penelitian ini adalah seluruh kelas XII IPS SMA Negeri 10 Semarang Tahun Ajaran 2013/2014. Metode pengumpulan data yaitu dengan menggunakan tes dan observasi. Pengujian hipotesis menggunakan uji paired sample t-tets dan independent sample t-test. Hasil penelitian menunjukkan peningkatan hasil belajar pada kelas eksperimen dilihat dari 61,16 meningkat mencapai 80,89. Selain itu menunjukkan hasil rata-rata nilai post-test sebesar 80,89 pada kelas eksperimen lebih tinggi dibandingkan nilai post-test sebesar 77,29 pada kelas kontrol. Berdasarkan hasil penelitian dapat disimpulkan bahwa pembelajaran dengan menggunakan metode pembelajaran drill berbantuan modul dapat meningkatkan hasil belajar serta efektif dalam meningkatkan hasil belajar siswa k ompetensi dasar jurnal khusus. Research purposes to determine the application of assisted modules drill method to improve learning outcomes of accounting competence base class XII IPS Special Journal SMA Negeri 10 Semarang school year 2013/2014. This study uses a quasi-experimental methods. The population in this study were all class XII IPS SMA Negeri 10 Semarang Academic Year 2013/2014. Data collection method is by using tests and observation. Hypothesis testing using paired sample t-tets and independent sample t-test. Results showed improved learning outcomes seen in the experimental classes increased to 80.89 from 61.16. In addition it shows the results of the average post-test score of 80.89 in the experimental class higher than the post -test score of 77.29 in the control class. Based on the results of this study concluded that learning by using drill -assisted learning modules to improve learning outcomes and effective in imp

  20. IMPLEMENTASI MODEL PEMBELAJARAN MIND MAP (PETA PIKIRAN) UNTUK MENINGKATKAN PRESTASI BELAJAR SISWA KELAS XII PADA MATA PELAJARAN RIAS WAJAH KHUSUS PROGRAM KEAHLIAN KECANTIKAN DI SMK NEGERI 27 JAKARTA PUSAT

    OpenAIRE

    ARINDIKA, RUSY

    2017-01-01

    ABSTRACT   Rusy Arindika 2012. Implementation Of The Mind Map Learning For Improving Student Achievement Against Class XII On the Subject Special Makeup Courses Beauty Expertise at SMKN 27 Jakarta. Thesis. Jakarta : Makeup Course, Department of Family Welfare, Faculty of Engineering, State University of Jakarta. The research was conducted based on action research or action research, which consisted of two cycles, where the description on each cycle include: planning action, impl...

  1. Molecular size is important for the safety and selective inhibition of intrinsic factor Xase for fucosylated chondroitin sulfate.

    Science.gov (United States)

    Yan, Lufeng; Li, Junhui; Wang, Danli; Ding, Tian; Hu, Yaqin; Ye, Xingqian; Linhardt, Robert J; Chen, Shiguo

    2017-12-15

    Fucosylated chondroitin sulfate from sea cucumber Isostichopus badionotus (FCS-Ib) showed potent anticoagulant activities without selectivity. The present study focused on developing safe FCS-Ib oligomers showing selective inhibition of intrinsic factor Xase (anti-FXase) prepared through partial N-deacetylation-deaminative cleavage. The N-deacetylation degree was regulated by reaction time, controlling the resulting oligomer distribution. Structure analysis confirmed the selectivity of degradation, and 12 high purity fractions with trisaccharide-repeating units were separated. In vitro anticoagulant assays indicated a decrease in molecular weight (Mw) dramatically reduced activated partial thromboplastin time (APTT), thrombin time (TT), AT-dependent anti-FIIa and anti-FXa activities, while the oligomers retained potent anti-FXase activity until they fell below 3kDa. Meanwhile, human FXII activation and platelet aggregation were markedly reduced with decreasing Mw and were moderate when under 12.0kDa. Thus, fragments of 3-12.0kDa should be safe and effective as selective inhibitors of intrinsic tenase complex for application as clinical anticoagulants. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Hubungan Asupan Energi Sarapan terhadap Tingkat Konsentrasi pada Siswa-Siswi Kelas XII SMA Negeri 1 Padang Tahun Ajaran 2013/2014

    Directory of Open Access Journals (Sweden)

    Kurnia Maidarmi Handayani

    2014-09-01

    Full Text Available AbstrakIndonesia menduduki peringkat terakhir dalam cognitive skills dan pencapaian pendidikan menurut penelitian yang dilakukan oleh Economist Intelligence Unit. Cognitive skills memerlukan fungsi otak yang adekuat yang dipertahankan oleh nutrisi berupa konsumsi pangan yang baik dan beragam, terutama sarapan. Penelitian di Amerika Serikat pada anak usia sekolah remaja (15-18 tahun menunjukkan bahwa sebesar 30% remaja tidak biasa sarapan. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan energi sarapan dan tingkat konsentrasi pada siswa SMAN 1 Padang. Studi dilakukan di SMAN 1 Padang pada bulan November 2013 terhadap 116 siswa kelas XII. Desain penelitian bersifat analitik dengan desain cross sectional. Pengolahan data dilakukan dengan uji chi-square menggunakan sistem komputerisasi. Hasil penelitian menunjukkan terdapat perbedaan tingkat konsentrasi menggunakan digit symbol test antara siswa dengan asupan energi sarapan baik, kurang, dan sangat kurang (p=0,001 dan tidak terdapat perbedaan tingkat konsentrasi menggunakan digit span test antara siswa dengan asupan energi sarapan baik, kurang, dan sangat kurang (p=0,345. Terdapat hubungan yang bermakna antara asupan energi sarapan dengan tingkat konsentrasi menggunakan digit symbol test (p<0,05.Kata kunci: sarapan, asupan energi, konsentrasi, digit symbol test, digit span testAbstractIndonesia was ranked last in the cognitive skills and educational attainment according to research conducted by the Economist Intelligence Unit.Cognitive skills require brain function is maintained by adequate intake of nutrients such as good and varied food, especially breakfast. Research in the United States in children of school age youth (15-18 years showed that 30% of teenagers are not usually did breakfast.This study aimed to determine the relationship between energy intake at breakfast and the level of concentration of students of SMAN 1 Padang. The study was conducted at SMAN 1 Padang in

  3. PENGARUH BIMBINGAN KARIR DAN LINGKUNGAN SEKOLAH MELALUI MOTIVASI KERJA TERHADAP KESIAPAN KERJA SISWA KELAS XII KOMPETENSI KEAHLIAN AKUNTANSI SMK NEGERI 2 MAGELANG

    Directory of Open Access Journals (Sweden)

    Muhammad Zachim Alfan

    2013-02-01

    Full Text Available Kesiapan kerja merupakan keseluruhan kondisi individu yang meliputi kematangan fisik, mental dan pengalaman serta adanya kemauan dan kemampuan untuk melaksanakan suatu pekerjaan atau kegiatan. Tujuan dari penelitian ini adalah untuk mengetahui ada tidaknya pengaruh bimbingan karir dan lingkungan sekolah melalui motivasi terhadap kesiapan kerja siswa kelas XII SMK Negeri 2 Magelang. Populasi penelitian ini adalah siswa kelas XII Kompetensi Keahlian Akuntansi SMK Negeri 2 Magelang Tahun Ajaran 2013/2014. Jumlah sampel sebanyak 84 siswa yang diambil dengan menggunakan rumus Isaac. Pengambilan sampel tiap kelas menggunakan proporsional random sampling. Metode pengumpulan data adalah angket. Metode analisis data menggunakan teknik analisis deskriptif, regresi linear berganda dan analisis jalur. Hasil penelitian menunjukkan bahwa terdapat pengaruh bimbingan karir terhadap kesiapan kerja siswa (48,1%, lingkungan sekolah berpengaruh terhadap kesiapan kerja siswa (33,5%, bimbingan karir berpengaruh terhadap motivasi kerja siswa (30,5%, ada pengaruh lingkungan sekolah terhadap motivasi kerja siswa (27%, bimbingan karir melalui motivasi kerja berpengaruh terhadap kesiapan kerja siswa (50,8%, dan lingkungan sekolah melalui motivasi kerja berpengaruh terhadap kesiapan kerja siswa (35,9%. The working readiness is the entire condition of an individual including physical maturity, mental maturity, experiential maturity, the existence of willingness and capability to do a job or activity. The purpose of this study is to know whether there is influence of career guidance and environmental school through motivation toward the working readiness of the twelfth graders who are taking accountancy program at State Vocational High School 2 Magelang. In this research, the population was the twelfth graders with year of education 2013/2014 who are taking accountancy program at State Vocational High School 2 Magelang. The population was the twelfth graders with year of

  4. PENGARUH KUALITAS POLA ASUH ORANG TUA, CARA BELAJAR, DAN MOTIVASI BELAJAR TERHADAP PRESTASI BELAJAR AKUNTANSI SISWA KELAS XI DAN XII KOMPETENSI KEAHLIAN AKUNTANSI SMK GATRA PRAJA KOTA PEKALONGAN TAHUN PELAJARAN 2013/2014

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    Eva Yulianti

    2014-11-01

    Full Text Available Prestasi belajar dipengaruhi oleh beberapa faktor, diantaranya yaitu kualitas pola asuh orang tua, cara belajar, dan motivasi belajar. Prestasi belajar akuntansi di SMK Gatra Praja Kota Pekalongan masih rendah. Masih ada 57 % siswa belum mencapai KKM yang ditetapkan sekolah yaitu ≥70. Tujuan penelitian ini untuk mengetahui adanya pengaruh kualitas pola asuh orang tua, cara belajar, dan motivasi belajar akuntansi di SMK Gatra Praja Kota Pekalongan baik secara parsial maupun simultan. Penelitian ini merupakan penelitian kuantitatif. Metode pengumpulan data menggunakan metode dokumentasi dan metode kuesioner. Metode analisis data menggunakan deskriptif persentase, regresi berganda, uji F, uji t, koefisien determinasi simultan(R2 dan koefisien determinasi parsial (r2. Hasil penelitian ini adalah secara parsial ada pengaruh kualitas pola asuh orang tua sebesar 16,2 %, cara belajar sebesar 6,4%, dan motivasi belajar sebesar 6,2% terhadap prestasi belajar akuntansi. Sedangkan secara simultan ada pengaruh kualitas pola asuh orang tua, cara belajar, dan motivasi belajar akuntansi di SMK Gatra Praja Kota Pekalongan tahun ajaran 2013/2014 sebesar 51,1%. Learning achievement is influenced by several factors, among which are quality of parents parenting, learning style, and learning motivation. Learning achievement of Accounting subjects in SMK Gatra Praja Pekalongan City is still low. There are still 57% students have not reached the KKM which has been established by the school is ≥70. The purpose of this study is to investigate the influence of quality of parents parenting, learning style, and learning motivation toward the learning achievement of Accounting subjects either partially or simultaneously. This research is quantitative research. Methods of data collection which are used are documentation and questionnaire method. Methods of data analysis using descriptive percentages, multiple regression, F test, t tes , and simultaneous determination

  5. Estrategias de subsistencia en los momentos finales del Pleistoceno medio: el nivel XII de la Cova del Bolomor (La Valldigna, Valencia

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    Ruth BLASCO

    2009-08-01

    Full Text Available RESUMEN: La Cova del Bolomor, situada en Tavernes de la Valldigna (Valencia, ofrece uno de los mejores registros faunísticos de la segunda mitad del Pleistoceno medio de la Península Ibérica. La cavidad contiene un relleno sedimentario formado por diecisiete niveles estratigráficos que abarcan desde el OIS 9 al OIS 5e. Esta amplia secuencia cronológica permite abordar diferentes cuestiones relacionadas con los grupos humanos de este periodo y sus relaciones con el medio ambiente. Concretamente, a partir del estudio zooarqueológico del nivel XII (OIS 6, se ha reconstruido la secuencia antrópica de obtención y procesamiento de los recursos faunísticos. De este modo, se han identificado diferentes estrategias de subsistencia llevadas a cabo por los homínidos para la obtención de los animales. Estas técnicas van desde el carroñeo hasta la caza e incluyen el aprovisionamiento de pequeñas presas como las aves (Cygnus olor o los lepóridos (Oryctolagus cuniculus. Esta variabilidad de estrategias podría interpretarse como la gran capacidad de adaptación que poseen estos grupos humanos para aprovechar las oportunidades que el medio les ofrece. También se ha observado la existencia de patrones bien sistematizados tanto en el aprovechamiento de los recursos faunísticos externos (piel, carne, tendones como en la obtención de los recursos internos (médula. Muchos de los elementos diagnósticos que evidencian la fracturación antrópica en el nivel XII presentan cierta sistematización en zonas y partes anatómicas concretas. La existencia de morfologías repetidas en algunos elementos esqueléticos indica una cierta estandarización a la hora de fracturar los huesos. Esta reiteración podría implicar la existencia de mecanismos de aprendizaje o de transmisión de información intergrupal por parte de los grupos humanos del Pleistoceno medio final. En general, este estudio pretende aportar datos sobre las estrategias de subsistencia de

  6. Homens de letras e homens de leis ao serviço da monarquia portuguesa (séculos XII-XIII

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    Armando Norte

    2014-06-01

    Full Text Available Ao longo da primeira dinastia, os letrados ao serviço da Coroa portuguesa desempenharam um papel decisivo e cada vez mais importante na afirmação do poder real. Homens de leis e homens de letras serviram à casa real como oficiais, representaram os reis portugueses em atos políticos e diplomáticos e exerceram um grande leque de funções na esfera da administração central - políticas, jurídicas, médicas, económicas, administrativas. A presença desses elementos ao lado dos monarcas fez-se sentir desde a fundação do reino, logo desde o reinado de D. Afonso Henriques, coincidindo o corolário deste processo de recrutamento com a chegada de D. Afonso III ao trono, numa política continuada, de forma firme, por D. Dinis. O conjunto de eruditos recenseados junto dos reis portugueses da época fundacional constitui, nessa medida, um interessante estudo de caso para compreender, em parte, em que consistia um círculo áulico, à luz dos valores do século XII e XIII.

  7. Preliminary report on AED deployment on the entire Air France commercial fleet: a joint venture with Paris XII University Training Programme.

    Science.gov (United States)

    Bertrand, C; Rodriguez Redington, P; Lecarpentier, E; Bellaiche, G; Michel, D; Teiger, E; Morris, W; Le Bourgeois, J P; Barthout, M

    2004-11-01

    The positive effect of early defibrillation on survival from cardiac arrest has been demonstrated. We describe the use of AEDs over 1 year following the training of flight attendants. Air France and the University of Paris XII together designed a 1 year training programme for 14000 flight attendants. The university emergency departments (SAMU) provided 250 instructors. AEDs training and certification was conducted for crew members between November 2001 and November 2002. By January 2003, all aircraft were fully equipped with AEDs. All cases of cardiac arrest that occurred during the study were reviewed comprehensively. Comments from the crew were collected. Twelve cardiac arrests were reported between November 2002 and November 2003 out of 4194 cases of emergency care delivered to passengers. Shock treatment was advised initially in 5/12 cases. The survival rate after in-flight cardiac arrest was 3/12. The survival rate at discharge from hospital following in flight shock was 2/5. No complications arose from the use of AEDs. Training by professionals gave the flight attendants confidence and allowed for the survival of two young passengers. Our study highlights the ability of flight attendants to give better onboard care for the future. The next step is to consolidate the network between in-flight care and the medical dispatch centre in Paris.

  8. A probable case of gigantism/acromegaly in skeletal remains from the Jewish necropolis of "Ronda Sur" (Lucena, Córdoba, Spain; VIII-XII centuries CE).

    Science.gov (United States)

    Viciano, Joan; De Luca, Stefano; López-Lázaro, Sandra; Botella, Daniel; Diéguez-Ramírez, Juan Pablo

    2015-01-01

    Pituitary gigantism is a rare endocrine disorder caused by hypersecretion of growth hormone during growing period. Individuals with this disorder have an enormous growth in height and associated degenerative changes. The continued hypersecretion of growth hormone during adulthood leads to acromegaly, a condition related to the disproportionate bone growth of the skull, hands and feet. The skeletal remains studied belong to a young adult male from the Jewish necropolis of "Ronda Sur" in Lucena (Córdoba, Spain, VIII-XII centuries CE). The individual shows a very large and thick neurocranium, pronounced supraorbital ridges, an extremely prominent occipital protuberance, and an extremely large and massive mandible. Additional pathologies include enlargement of the vertebral bodies with degenerative changes, thickened ribs, and a slight increased length of the diaphysis with an increased cortical bone thickness of lower limbs. Comparative metric analysis of the mandible with other individuals from the same population and a contemporary Mediterranean population shows a trend toward acromegalic morphology. This case is an important contribution in paleopathological literature because it is a rare condition that has not been widely documented in ancient skeletal remains.

  9. PENERAPAN MODEL PEMBELAJARAN THINK PAIR SHARE DENGAN PENDEKATAN INKUIRI UNTUK MENINGKATKAN MOTIVASI DAN HASIL BELAJAR IPA PADA SISWA KELAS XII SMK

    Directory of Open Access Journals (Sweden)

    Beny Yulianingsih

    2017-01-01

    Penelitian ini bertujuan untuk meningkatkan motivasi dan hasil belajar siswa yang menggunakan model pembelajaran Think Pair Share (TPS dengan pendekatan inkuiri. Penelitian ini termasuk penelitian tindakan kelas yang dilaksanakan dalam dua siklus. Subjek penelitian adalah siswa kelas XII SMK NU Tenggarang Bondowoso tahun ajaran 2016/2017. Data penelitian diperoleh melalui observasi dan tes. Hasil penelitian menunjukkan terjadi peningkatan motivasi siswa dari siklus I ke siklus II sebesar 69,69% dengan rincian pada aspek attention sebesar 73,16% pada siklus I menjadi 92,53% pada siklus II, pada aspek relevance sebesar 79,20% pada siklus I menjadi 95,07% pada siklus II, pada aspek confidence sebesar 73,70% pada siklus I menjadi 89,40% pada siklus II, dan pada aspek satisfaction sebesar 72,69% pada siklus I menjadi 91,43% pada siklus II. Begitupula hasil belajar afektif yang diperoleh selama proses pembelajaran berlangsung juga mengalami peningkatan persentase yaitu 76,22% pada siklus I dan 83,67% pada siklus II. Untuk keterlaksanaan proses pembelajaran juga menunjukkan peningkatan dari 92,22% pada siklus 1 dan 95,66% pada siklus II. Dengan demikian, hasil ini menunjukkan bahwa model pembelajaran kooperatif TPS dengan pendekatan inkuiri dapat meningkatkan motivasi dan hasil belajar siswa.

  10. Effects on coagulation factor production following primary hepatomitogen-induced direct hyperplasia.

    Science.gov (United States)

    Tatsumi, Kohei; Ohashi, Kazuo; Taminishi, Sanae; Takagi, Soichi; Utoh, Rie; Yoshioka, Akira; Shima, Midori; Okano, Teruo

    2009-11-14

    To investigate the molecular mechanisms involved in coagulation factor expression and/or function during direct hyperplasia (DH)-mediated liver regeneration. Direct hyperplasia-mediated liver regeneration was induced in female C57BL/6 mice by administering 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene (TCPOBOP), a representative hepatomitogen. Mice were weighed and sacrificed at various time points [Day 0 (D0: prior to injection), 3 h, D1, D2, D3, and D10] after TCPOBOP administration to obtain liver and blood samples. Using the RNA samples extracted from the liver, a comprehensive analysis was performed on the hepatic gene expression profiling of coagulation-related factors by real-time RT-PCR (fibrinogen, prothrombin, factors V, VII, VIII, IX, X, XI, XII, XIIIbeta, plasminogen, antithrombin, protein C, protein S, ADAMTS13, and VWF). The corresponding plasma levels of coagulation factors (fibrinogen, prothrombin, factors V, VII, VIII, IX, X, XI, XII, XIII, and VWF) were also analyzed and compared with their mRNA levels. Gavage administration of TCPOBOP (3 mg/kg body weight) resulted in a marked and gradual increase in the weight of the mouse livers relative to the total body weight to 220% by D10 relative to the D0 (control) ratios. At the peak of liver regeneration (D1 and D2), the gene expression levels for most of the coagulation-related factors (fibrinogen, prothrombin, factors V, VII, VIII, IX, XI, XII, XIIIbeta, plasminogen, antithrombin, protein C, ADAMTS13, VWF) were found to be down-regulated in a time-dependent manner, and gradually recovered by D10 to the basal levels. Only mRNA levels of factor X and protein S failed to show any decrease during the regenerative phase. As for the plasma levels, 5 clotting factors (prothrombin, factors VIII, IX, XI, and XII) demonstrated a significant decrease (Pfactors, factor IX and factor XI showed the most dramatic decline in their activities by about 50% at D2 compared to the basal levels, and these reductions in

  11. Radiation-induced cranial nerve palsy and its causative factors in nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Kong Lin; Zhang Youwang; Wu Yongru; Guo Xiaomao; Li Longgen

    2005-01-01

    Objective: To analyze the incidence and causative factors of radiation-induced cranial nerve palsy in patients with nasopharyngeal carcinoma (NPC). Methods: 512 NPC patients who underwent radiotherapy from January 1, 1989 to December 31, 1990 and from January 1, 1994 to December 31, 1995 were retrospectively analyzed. According to Fuzhou' 92 NPC Staging Classification, there are 31 patients in stage I, 212 in stage II, 198 in stage III and 71 in stage IV. All patients were treated by 60 Co or 6 MV X-ray with faciocervical fields or pre-auricular fields to primary area. Some patients were boosted by post-auricular fields or cranial fields. The median dose to the nasopharyngeal region was 7130 cGy by external beam radiotherapy. Thirty-four patients were boosted by brachytherapy. The medial dose to cervical lymph nodes was 6410 cGy as definitive treatment and 5480 cGy as prophylactic treatment. 101 patients were treated with combined chemotherapy. Results: The median follow-up was 6.7 years . Radiation-induced cranial nerve palsies occurred in 81 among the 512 patients. The 5- and 10-year cumulative incidences were 10.3%, 25.4%, respectively. The most common affected nerve was XII. On multivariates analysis, cranial nerve invasion before radiation, chemotherapy, dose to the nasopharyngeal region and age were the independent factors of radiation-induced cranial nerve palsy on nerve I-VII, while the N stage and the radiation fields were independent factors on nerve IX-XII. The cumulative incidence of cranial nerve I-VII palsies increased in patients with cranial nerve invasion, chemotherapy and the dose to the nasopharyngeal region (>7000 cGy). The cumulative incidence of cranial nerve IX- XII palsies increased in patients with advanced N stage. Patients in the first group of treatment field had the highest risk to progress cranial nerve IX-XII palsies, followed by the second group, and the third group had the lowest risk. Only 1 in 34 patients with brachytherapy

  12. L'autografia d'autore Cambiamenti nella realizzazione e nella concezione del libro dal XII secolo all'invenzione della stampa

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    Micol Long

    2012-06-01

    Full Text Available Si ritiene a volte che l'invenzione della stampa abbia innescato il cambiamento nel modo di concepire l'oggetto libro, segnando il passaggio dall'idea medievale a quella moderna. Occorre però tenere presente che esiste un'importante evoluzione interna al medioevo e che l'invenzione della stampa, per quanto fondamentale, è da inserire all'interno di questo processo più ampio, che a partire dal XII secolo circa trasforma l'uso e la funzione stessa della scrittura, rivoluziona il modo di leggere e di conseguenza il libro stesso, sia concettualmente sia come oggetto fisico. L'approccio scelto per questo studio mira a risalire alle radici culturali dei cambiamenti nelle pratiche del lavoro intellettuale e, viceversa, a indagare se e come tali cambiamenti abbiano potuto influenzare, attraverso le opere stesse, la cultura dell'epoca. Il fenomeno oggetto specifico dell'indagine è l'autografia letteraria d'autore che, eccezionale nell'alto medioevo, è testimoniata da una nuova e ininterrotta serie di casi a partire dall'XI-XII secolo, per poi diffondersi nei secoli successivi. Il panorama culturale della fine del medioevo appare dunque caratterizzato dalla tensione tra una ricorrente aspirazione all'individualizzazione del rapporto tra l'autore e il suo testo, che si realizzava in un modello di produzione libraria basato su uno stretto controllo dell'autore sul prodotto finale, dal punto di vista sia filologico-testuale sia grafico e materiale, e l'opposta tendenza all'allentamento del controllo dell'autore sulla propria opera, come naturale conseguenza di una sempre più vasta circolazione dei testi ma anche di una diversa concezione del ruolo autoriale. It is generally believed that the invention of printing triggered a cultural change, marking the passage between the medieval idea of the book and the modern one. It should be noted, though, that there was an important evolution through the Late Middle Ages, and that the printing revolution

  13. Las mujeres nobles y el poder en los reinos de León y Castilla en el siglo XII: un estudio preliminar

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    Simon BARTON

    2012-03-01

    Full Text Available El presente artículo analiza hasta qué punto las mujeres pertenecientes a la aristocracia eran capaces de ostentar el poder y ejercer su influencia en el ámbito de los reinos de León y Castilla durante el siglo XII. Pese a ser cierto que el acceso de las mujeres nobles al poder y al ejercicio de influencias se encontraba limitado por cuestiones de género, lo cual implicaba que se encontraban prácticamente excluidas de determinadas esferas de actividad relevantes, tales como la pertenencia a la curia real, estas mujeres estaban lejos de ser meras víctimas pasivas del dominio masculino, como a menudo se ha supuesto. Gracias a sus considerables recursos económicos, que administraban a través de las instituciones entrelazadas del señorío y la familia, y a su estrecha relación con la Iglesia, dichas mujeres estaban capacitadas para desempeñar papeles destacados en el ámbito público y ejercer un grado importante de poder y autoridad en su paso por el ciclo vital que iba desde el matrimonio hasta la viudedad. Dicho papel público no necesariamente se volvía más limitado tras la muerte del marido; si acaso, ganaba importancia, ya que las madres continuaban ofreciendo su apoyo a sus hijos y ejercían el mecenazgo, especialmente el religioso, a una escala sin precedentes.

  14. A Keck/DEIMOS spectroscopic survey of the faint M31 satellites AndIX, AndXI, AndXII and AndXIII†

    Science.gov (United States)

    Collins, M. L. M.; Chapman, S. C.; Irwin, M. J.; Martin, N. F.; Ibata, R. A.; Zucker, D. B.; Blain, A.; Ferguson, A. M. N.; Lewis, G. F.; McConnachie, A. W.; Peñarrubia, J.

    2010-10-01

    We present the first spectroscopic analysis of the faint M31 satellite galaxies, AndXI and AndXIII, as well as a re-analysis of existing spectroscopic data for two further faint companions, AndIX (correcting for an error in earlier geometric modelling that caused a misclassification of member stars in previous work) and AndXII. By combining data obtained using the Deep Imaging Multi-Object Spectrograph (DEIMOS) mounted on the Keck II telescope with deep photometry from the Suprime-Cam instrument on Subaru, we have identified the most probable members for each of the satellites based on their radial velocities (precise to several down to i ~ 22), distance from the centre of the dwarf spheroidal galaxies (dSphs) and their photometric [Fe/H]. Using both the photometric and spectroscopic data, we have also calculated global properties for the dwarfs, such as systemic velocities, metallicities and half-light radii. We find each dwarf to be very metal poor ([Fe/H] ~ -2 both photometrically and spectroscopically, from their stacked spectrum), and as such, they continue to follow the luminosity-metallicity relationship established with brighter dwarfs. We are unable to resolve dispersion for AndXI due to small sample size and low signal-to-noise ratio, but we set a 1σ upper limit of σv financial support of the W.M. Keck Foundation. Based in part on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. ‡ E-mail: mlmc2@ast.cam.ac.uk

  15. CORRELATION OF INTEREST TO LEARN AND USE TIME LEARNING WITH LEARNING ACHIEVEMENT AUTOMOTIVE ELECTRICAL IN CLASS XII LIGHT VEHICLE ENGINEERING SMK PIRI I YOGYAKARTA ACADEMIC YEAR 2013/2014

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    Ari Pujiatmoko

    2014-06-01

    Full Text Available The purpose of this study were: 1 to determine whether there is a correlation between students' interest in learning and the learning achievement of automotive electrical, 2 to determine whether there is a correlation between the use of time studying the learning achievement of automotive electrical, 3 to determine whether there is a correlation between student interest and use the time to learn and the learning achievement of students of class XII automotive electrical TKR SMK PIRI 1 Yogyakarta academic year 2013/2014.  This research was conducted in class XII TKR SMK PIRI 1 Yogyakarta academic year 2013/2014. This study is an ex-post facto. This study used two independent variables and the interest in learning the use of learning time, while the dependent variable is the electrical automotive learning achievement. This study is a population study by the respondent amounted to 100 students. Techniques of data collection using questionnaire techniques and engineering documentation. Research instrument in this study is a questionnaire interest in learning, inquiry learning time management and documentation of student achievement. Trials using the instrument validity and reliability test. The analysis technique used is the prerequisite test for normality, linearity, and multicollinearity. Then test hypotheses using partial correlation analysis techniques and correlation.  The results showed that: 1 students' interest to have a strong positive correlation with school performance automotive electrical ρ value of 0.737; 2 the use of learning time have a low positive correlation with school performance automotive electrical ρ value of 0.275; 3 interest student learning and the use of study time has a very strong positive correlation with learning achievement of students of class XII automotive electrical TKR SMK PIRI I Yogyakarta academic year 2013/2014 as evidenced by the value of R = 0.811.

  16. Incidencia del aprendizaje cooperativo en el área de Lenguaje y Comunicación en el séptimo año de la escuela Pío XII periodo lectivo 2007-2008

    OpenAIRE

    Alvarez Carvajal, Esthela del Rocío; Robles Tenorio, Mercy Cristina

    2007-01-01

    Lo que recoge este documento va dirigido al aprendizaje desde un punto de vista cooperativo como parte de la formación integral del alumnado de la escuela PIO XII. Por lo que consideramos fundamental al aprendizaje cooperativo como: una estrategia de enseñanza exitosa en la que pequeños grupos, cada uno con estudiantes de diferentes niveles de habilidad usan una variedad de actividades de aprendizaje para mejorar su comprensión de un tema. Cada miembro de un equipo es responsable no sólo de a...

  17. Sprawozdanie z XII Międzynarodowej Konferencji pt. „Edukacja a nowe technologie w kulturze, informacji i komunikacji” (Toruń, 09–10.06.2015)

    OpenAIRE

    Kwiatkowska, Wioletta

    2016-01-01

    W dniach 9−10 czerwca 2015 roku odbyła się XII Międzynarodowa Konferencja Naukowa z cyklu „Technologia informacyjna w zmieniającej się edukacji”. Temat przewodni konferencji brzmiał: „Edukacja a nowe technologie w kulturze, informacji i komunikacji”. W tej edycji konferencji poruszane były zagadnienia dotyczące nowych technologii i ich znaczenie dla edukacji. Inicjatywy o takim charakterze podejmowane od kilkunastu lat przez Katedrę Dydaktyki i Mediów w Edukacji wpisały się w tradycję Wydział...

  18. “Et qui or me vaurra entendre, cuer et oreilles me doit rendre”: espacios de lectura y público de los roman courtois de Chrétien de Troyes (siglos XII-XIII

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    Diego Carlo Améndolla Spinola

    2016-06-01

    Full Text Available Basado en los planteamientos de la lógica social del texto, este artículo presenta un estudio del público que escuchaba los romances corteses entre los siglo XII y XIII, específicamente los realizados por Chrétien de Troyes –clérigo lector de la Corte de Leonor de Aquitania y de Enrique II Plantagenet–, además de establecer y analizar las diversas salas de los castillos donde estas obras literarias eran narradas.

  19. AN ANALYSIS OF STUDENTS’ ABILITY IN USING SUB-ORDINATE CONJUNCTION IN SENTENCE WRITING OF THE GRADE XII STUDENTS OF SMA N 2 METRO ACADEMIC YEAR 2013/2014

    OpenAIRE

    Bambang Eko Siagianto

    2017-01-01

    Abstracts: Sub-ordinate conjunction is very confusing to comprehend by students. In using sub-ordinate conjunction, students usually had errors. The purpose of this research to analyze whether or not the students are able to use sub-ordinate conjunction in sentence writing, to classify kinds of sub-ordinate conjunction that was often misused by students in sentence writing The research was done at the grade XII of SMA N 2 Metro in second semester of the academic year 2013/2014. The predicted ...

  20. ESTUDIOS METODOLÓGICOS DEL EFECTO DEL REGADÍO SOBRE LA CALIDAD DE LAS AGUAS DE LAS MASAS ASOCIADAS A UNA ZONA REGABLE: EL CASO DEL SECTOR B-XII DE LA ZONA REGABLE DEL BAJO GADALQUIVIR

    OpenAIRE

    Martínez Beltrán, J.

    2015-01-01

    [ES] El objeto del estudio ha sido determinar los efectos de la agricultura de regadío del Sector B-XII en la detracción de agua del Guadalquivir y en los contenidos de sales y nitratos de sus aguas en el tramo asociado a este sector, así como en el agua subterránea subyacente. La dotación de agua asignada en la campaña 2012-2013 ha sido inferior a la calculada para satisfacer las necesidades de agua de riego de los cultivos y el control de la salinidad de los suelos. La detrac...

  1. International Congress on Glass XII

    Energy Technology Data Exchange (ETDEWEB)

    Doremus, R H; LaCourse, W C; Mackenzie, J D; Varner, J R; Wolf, W W [eds.

    1980-01-01

    A total of 158 papers are included under nine headings: structure and glass formation; optical properties; electrical and magnetic properties; mechanical properties and relaxation; mass transport; chemical durability and surfaces; nucleation; crystallization; and glass ceramics; processing; and automatic controls. Separate abstracts were prepared for eight papers; four of the remaining papers had been processed previously for the data base. (DLC)

  2. Laser Spectroscopy : XII International Conference

    CERN Document Server

    Allegrini, Maria; Sasso, Antonio

    1996-01-01

    This text includes all the recent advances in the field of laser spectroscopy. Major results span from the control of matter by electromagnetic fields (trapping and coding) to high precision measurements on simple atomic systems and to quantum optics with single atoms. It includes a report of the Bose-Einstein condensation achieved by laser-cooling of rubidium atoms. Achievements in the technology of tunable sources, in particular of miniaturized solid state devices, are also reported. Most recent advances in molecular spectroscopy are illustrated with emphasis on "cooled" spectra, clusters and high accuracy frequency references. Topics such as atomic interferometry and microcavity quantum optics are also covered.

  3. Factors affecting radiocaesium transfer to ruminants

    International Nuclear Information System (INIS)

    Voigt, G.; Howard, B.J.; Vandecasteele, C.; Mayes, R.W.; Belli, M.; Sansone, U.; Stakelum, G.; Colgan, P.A.; Assimakopoulos, P.; Crout, N.M.J.; Jones, B.E.V., Hove, K.; ITE, Merlewood; CEN, Mol; MLURI, Aberdeen; ENEA-DISP, Rome; MPRC, Fermoy; RPII, Dublin; Ioannina Univ., Nuclear Physics; Nottingham Univ., Dept. of Environmental Sciences; Swedish Univ. of Agricultural Sciences, Uppsala; Agricultural Univ., Aas

    1993-01-01

    The studies performed in the 2 year CEG/DG XII Radiation Protection Programme described here have tried to identify and quantify some of the most important factors influencing the radiocaesium levels in animal food products. The programme involved 9 laboratories in 6 countries: Belgium, Ireland, Greece, Italy, Sweden and the UK. Scientists from Norway and Germany also participated on an informal basis and are formally involved in a subsequent project. Experimental studies have largely been conducted using sheep, although some comparative studies have been performed with dairy cattle. In parallel to the experimental studies, a number of research models have been developed by participants in Greece and the UK to be interactively used with a number of different aspects in the programme. This presentation gives a short overview and discussion of the main findings of this project. (orig./DG)

  4. Vides de Simón de Rojas Clemente (1777-1827 en el herbario del Real Colegio Alfonso XII de San Lorenzo de El Escorial (Madrid, España

    Directory of Open Access Journals (Sweden)

    Perea, Domingo

    1997-12-01

    Full Text Available In the present paper, the discovery of grape-vine mounted sheets from the Simón de Rojas Clemente herbarium, which were found in the Herbarium of the Real Colegio Alfonso XH in San Lorenzo de El Escorial, is reported. This material completes the collection of Clemente's vines which makes up one of the historical collections deposited in the MA herbarium.Damos a conocer unos pliegos de vides procedentes del herbario de Simón de Rojas Clemente que han aparecido en el Gabinete de Ciencias Naturales del Real Colegio Alfonso XII de San Lorenzo de El Escorial. Estos materiales completan la colección de vides de Clemente que constituye uno de los herbarios históricos depositados en MA.

  5. AN ANALYSIS OF STUDENTS’ ABILITY IN USING SUB-ORDINATE CONJUNCTION IN SENTENCE WRITING OF THE GRADE XII STUDENTS OF SMA N 2 METRO ACADEMIC YEAR 2013/2014

    Directory of Open Access Journals (Sweden)

    Bambang Eko Siagianto

    2017-02-01

    Full Text Available Abstracts: Sub-ordinate conjunction is very confusing to comprehend by students. In using sub-ordinate conjunction, students usually had errors. The purpose of this research to analyze whether or not the students are able to use sub-ordinate conjunction in sentence writing, to classify kinds of sub-ordinate conjunction that was often misused by students in sentence writing The research was done at the grade XII of SMA N 2 Metro in second semester of the academic year 2013/2014. The predicted research findings are; the students cannot divide or difference the type of sub-ordinate conjunction well, and they often errors using it in sentences.The result of the students test in using sub-ordinate conjunction in sentence writing proves that most of the students at the grade XII of SMA N 2 Metro used the list of words “after, then, when, because” on their sentence writing. The students found these words easier to be used as conjunction especially sub-ordinate conjunction in their sentence writing than other conjunction. While, for other list of words doesn’t used by the students because the students cannot adapted the words in their sentence writing. The most familiar sub-ordinate conjunction seems to be  “before and since” (each of them is gained by 22 students = 91,6%, but the students are unfamiliar with the other words in sub-ordinate conjunction mainly “till and unless” (each of the is gained by 13 students = 54,1%. The other sub-ordinate conjunctions are quite familiar for them.

  6. How Do R&D Programs Funded by the Dg Xii (Science, Research and Development Directorate of the European Commission Impact the Upstream Oil and Gas Industry in Europe? Comment les programmes de R&D financés par la DG XII de la Commission européenne influencent-ils l'industrie pétrolière amont en Europe ?

    Directory of Open Access Journals (Sweden)

    Forbes P.

    2006-12-01

    Full Text Available This paper provides an overview of the direct and indirect impact which DG XII funding for research and development has on the oil and gas exploration and production industry in Europe. Despite the relatively low level of funding, the impact is quite significant. These impacts are presented using a bottom-up analysis, starting with the impact of technology on industry and society, the impact of research on technology, and the impact of DG XII funding on both research and technology for the exploration and production of oil and gas. The different aspects that are discussed include the direct impact, the impact on R&D organization and management, and the impact due to the Commission demonstration program for oil and gas (Thermie. Examples are provided from current and past project results. The future impact on the industry, and Commission policy toward the oil and gas sector are suggestedIn the near future, it is expected that there will be greater impact on production technologies, on the contribution of oil and gas companies to long-term R&D, and on the transfer of results to the Commission demonstration program. L'article apporte une vue d'ensemble sur la manière dont les financements de la DG XII pour la recherche et le développement (R&D ont une influence, directe ou indirecte, sur l'exploration et la production dans l'industrie du pétrole et du gaz en Europe. Le niveau de ces financements est présenté comme relativement faible de façon à mettre en évidence que, comparativement, leur répercution est très significative. L'impact de ces financements est abordé en couvrant successivement les effets sur la société, l'industrie, la technologie et finalement la recherche elle-même. Nous décrivons ici les influences de la technologie sur l'industrie et sur la société, puis les influences de la recherche sur la technologie et enfin celles des financements de la DG XII sur la recherche et la technologie en exploration-production. Diff

  7. Disputes i compromisos entre l'església de Girona i la noblesa: Notes d'unes difícils relacions. Segles XI i XII

    Directory of Open Access Journals (Sweden)

    Salrach, Josep M.

    1999-12-01

    Full Text Available In this article are studied the disputes or conflicts between the ecclesiastic hierarchy and the aristocracy of the country of Girona in the era of the feudal change. The sources of information are the documents of the XI-XII Century of the Chartulary call of "Carlemany", of the bishop of Girona, edited by J. M. Marqués, and the documents of the XI Century of the cathedral of Gerona, edited by R. Marti. The article is split into two parts of unequal extension. In the first, the shortest, it is summarised the problem of the relationships between the Church and the civil power in the Late Antiquity and the High Middle Ages, until the XIXII Century. The approach is general, European, but is ended this part carrying the problems to the case of Catalonia. It is a study of the context in the one which the author attempts to find the bases of the attitude of the feudal nobility in theirs disputes with the Church. In the second part of the article are studied the disputes and the engagements (more the first tan the seconds between the cathedral of Gerona and the nobility. The analysis and the description are not effected in a way concrete, examining a dispute after other, that is to say. there is no studies of cases with lineages and personages identification, because prevails the global vision and the will of identifying the principal disputes and the general and dominant reasons of each part. The questions that they have guided the investigation are: With what obstacles stumbled the reform of the Church? Which were the concrete causes of the disputes? How they were solved these disputes? Which were the political bases, material, spiritual and cultural on those which the Church of Gerona sustained their engagements with the nobility? How they were articulated these engagements? Turned out to be it a work that interprets the reform of the Church in the framework of the feudal change process, and arrives to the conclusion of the fact that the reform was

  8. Consilium y fortalecimiento regio: consejeros y acción política regia en el reino de León en los siglos XI y XII

    Directory of Open Access Journals (Sweden)

    Fernando Luis Corral

    2011-11-01

    Full Text Available Este trabajo pretende ver la relación existente entre el acto de aconsejar y la realidad de la acción política regia en el reino leonés durante los siglos XI y XII. Como es sabido, el consejo formaba parte de los formulismos vasalláticos –consilium et auxilium– que definían la relación que se establecía entre la nobleza y la monarquía fundamentalmente a través de los juramentos de homenaje en los que la nobleza reconocía, al menos teóricamente, la superioridad del rey como su señor. El monarca, a su vez, por la fidelidad que los nobles le juraban controlaba sus movimientos aunque se veía obligado a recompensarles adecuadamente sus servicios para ganarse su apoyo. Pero a finales del siglo XII, estos formulismos vasalláticos de los que el consilium era un elemento importante se comenzaron a mostrar ineficaces para contrarrestar el poder político de la nobleza y sus movimientos cada vez más autónomos rompiendo su fidelitas con el rey. Paulatinamente la monarquía leonesa utilizó nuevas estrategias de control que, incorporando el Derecho Romano a sus formulaciones teóricas legales, la situó en una posición inmejorable para introducir elementos nuevos de organización y administración del territorio, como los tenentes y merinos regios. Éstas y otras actuaciones fueron determinantes en el fortalecimiento regio que experimentaron los monarcas leoneses durante el siglo XII.Ce travail porte sur le rapport entre l'acte de conseiller et la réalité de l'action politique royale dans le royaume de León au cours des XIe et XIIe siècles. Le conseil apparaît dans les formules qui, comme “consilium et auxilium”, définissent la relation entre la noblesse et la monarchie, essentiellement dans les serments accompagnant l'hommage vassalique et par lesquels la noblesse reconnaissait, du moins théoriquement, la supériorité du roi en tant que seigneur. Grâce à la fidélité que les nobles lui juraient, le monarque exer

  9. Characterisation of clotting factors, anticoagulant protein activities and viscoelastic analysis in healthy donkeys.

    Science.gov (United States)

    Perez-Ecija, A; Mendoza, F J

    2017-11-01

    Studies have demonstrated differences in commonly measured haemostatic parameters between donkeys and horses. Whether clotting factors, anticoagulant protein activities and thromboelastography parameters also differ between species is still unknown. To characterise haemostatic parameters in healthy donkeys and to compare these with those in horses. Cross-sectional study. Clotting factors (V, VII, VIII, IX, X, XI and XII), and antithrombin III, Protein C and Protein S activities were measured in 80 healthy Andalusian and crossbred donkeys and 40 healthy Andalusian crossbred horses with assays based on human deficient plasmas. Thromboelastography was performed in 34 donkeys using a coagulation and platelet function analyser. Donkeys had shorter activated partial thromboplastin time (mean ± s.d. 33.4 ± 5.2 s vs. 38.8 ± 4.2 s; P0.05) and XII (96 ± 21 vs. 108 ± 15; Pdonkeys. Activated clot time (175 [159-189]), time to peak (6.5 [5.8-7.8]) and clot formation rate (26.9 [16.9-36.4]) in donkeys were shorter than reported values in horses. Haemostatic pathways could not be fully evaluated in donkeys because some tests are unavailable. Certain fibrinolytic parameters (plasmin, plasminogen, etc.) have not been characterised in donkeys and this may have affected our results. The haemostatic system in donkeys differs from that in horses and extrapolation of reference values between these species is not appropriate. © 2017 EVJ Ltd.

  10. PENGARUH PRESTASI AKADEMIK MATA DIKLAT PRODUKTIF AKUNTANSI, PRAKTIK KERJA INDUSTRI, DAN LINGKUNGAN KELUARGA TERHADAP KESIAPAN KERJA SISWA KELAS XII SMK NEGERI 1 KEBUMEN PROGRAM KEAHLIAN AKUNTANSI TAHUN AJARAN 2014/2015

    Directory of Open Access Journals (Sweden)

    Ulinnajah Sofia Handayani

    2015-11-01

    Full Text Available SMK merupakan salah satu lembaga pendidikan kejuruan yang diselenggarakan dalam rangka mempersiapkan calon tenaga kerja untuk bekerja dalam bidang tertentu. Data SMK N 1 Kebumen menunjukkan adanya peningkatan lulusan SMK yang belum mendapatkan pekerjaan dari tahun 2013 ke 2014 sebesar 4%. Tujuan dari penelitian ini adalah untuk mengetahui ada tidaknya pengaruh prestasi akademik mata diklat produktif akuntansi, praktik kerja industri, dan lingkungan keluarga terhadap kesiapan kerja siswa kelas XII SMK Negeri 1 Kebumen program keahlian akuntansi.Populasi penelitian ini adalah siswa kelas XII Akuntansi sejumlah 120 siswa dan jumlah sampel sebanyak 92 siswa yang diambil dengan teknik pengambilan sampel proportional Random Sampling. Metode yang digunakan dalam pengambilan data adalah angket dan dokumentasi. Data variabel dianalisis dengan regresi berganda. Hasil penelitian ini menunjukkan bahwa terdapat pengaruh prestasi akademik mata diklat produktif akuntansi, praktik kerja industri dan lingkungan keluarga terhadap kesiapan kerja siswa SMK Negeri 1 Kebumen sebesar 34,3%. Prestasi akademik mata diklat produktif akuntansi berpengaruh sebesar 6,16%. Praktik kerja industri berpengaruh sebesar 25,4%. Sedangkan lingkungan keluarga berpengaruh sebesar 9,86%. Vocational High School one of the educational institution that prepares the students to work in particular filed. Data of vocational high school 1 Kebumen show the increase students graduated from vocational high school have not gotten the job yet from 2013 to 2014 with amount 4%. The purpose of this study is to know whether there is influence of academic achievement accounting productive subject, on the job trining, and environmental family toward working readiness of the twelfth graders at state vocational high school 1 Kebumen who are taking accountancy program. The population in this study were students twelfth graders who are taking accountancy program with amount 120 students and the members of

  11. PENGARUH MOTIVASI, PRESTASI BELAJAR, STATUS SOSIAL EKONOMI ORANG TUA DAN LINGKUNGAN TEMAN SEBAYA TERHADAP MINAT MELANJUTKAN PENDIDIKAN KE PERGURUAN TINGGI PADA SISWA KELAS XII KOMPETENSI KEAHLIAN AKUNTANSI DI SMK NEGERI SE-KOTA SEMARANG TAHUN AJARAN 2014/

    Directory of Open Access Journals (Sweden)

    Nabila Kharisma

    2015-11-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui apakah terdapat pengaruh positif motivasi, prestasi belajar, status sosial ekonomi dan lingkungan teman sebaya terhadap minat melanjutkan pendidikan ke perguruan tinggi pada siswa kelas XII kompetensi keahlian akuntansi di SMK Negeri se-Kota Semarang baik secara simultan maupun parsial. Populasi dalam penelitian ini adalah seluruh siswa kelas XII Kompetensi Keahlian Akuntansi di SMK Negeri se-Kota Semarang tahun ajaran 2014/2015 yang berjumlah 213 siswa. Metode pengambilan sampel menggunakan teknik proportional random sampling dengan jumlah responden sebanyak 135 siswa. Metode pengumpulan data menggunakan angket dan dokumentasi. Sedangkan metode analisis data yang digunakan adalah analisis deskriptif dan pengujian hipotesis menggunakan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa terdapat pengaruh motivasi, prestasi belajar, status sosial ekonomi orang tua, dan lingkungan teman sebaya secara simultan berpengaruh sebesar 71,5% terhadap minat melanjutkan pendidikan ke perguruan tinggi. Sedangkan motivasi berpengaruh sebesar 17,47% terhadap minat melanjutkan pendidikan ke perguruan tinggi secara parsial, prestasi belajar berpengaruh sebesar 23,91% terhadap minat melanjutkan pendidikan ke perguruan tinggi secara parsial , status sosial ekonomi orang tua berpengaruh sebesar 16,81% terhadap minat melanjutkan pendidikan ke perguruan tinggi secara parsial, dan lingkungan teman sebaya berpengaruh sebesar 10,50% terhadap minat melanjutkan pendidikan ke perguruan tinggi secara parsial. This research aims to determine the level of positive influence between motivation, academic achievement, socio economic status of parents and peers environment on interest in continuing education to the collage of 12th Accounting Program Students at State Vocational High School of Semarang City in 2014/2015. Populations in this research is students at State Vocational High School of Semarang city specially 12

  12. Gramíneas uruguayas de D. José Arechavaleta (1838-1912, en el Real Colegio Alfonso XII de San Lorenzo de El Escorial (Madrid, España

    Directory of Open Access Journals (Sweden)

    Carrasco, María A.

    2001-12-01

    Full Text Available The Royal Monastery of El Escorial was built in the xvi century by king Felipe U. In the part intended to be a college and seminary, the Real Colegio Alfonso XII was established in 1885. In this place, the treasures that had been accumulated for fíve hundred years, that carne from acquisitions, collections and donations, are stored. In this paper we present a small collection, of undeniable historical valué. It contains 186 Gramineae that were sent as a present to María Cristina, the Regent Queen of Spain, by the President of Uruguay on the occasion of the World Exhibition of Barcelona in 1888. The plants are part of the herbarium of the Flora Uruguaya of José Arechavaleta y Balparda [Santurce (España, 1838-Montevideo (Uruguay, 1912]. Some of the plants are annotated by Arechavaleta as new species, and some belong from the loc. clas. All this material is identified by Arechavaleta and J. Hackel.El Real Monasterio de El Escorial fue fundado en el siglo XVI por el rey Felipe n. En la parte dedicada a colegio-seminario se estableció en 1885 el Real Colegio Alfonso XII, donde están depositados todos los fondos que se han ido acumulando a lo largo de quinientos años, procedentes de adquisiciones, recolecciones y donaciones. En este trabajo presentamos una colección, pequeña pero de indudable valor histórico, de 186 Gramineae que fueron enviadas por el presidente del Uruguay a la reina regente de España con motivo de la Exposición Universal de Barcelona celebrada en 1888. Estos materiales son parte del herbario de la Flora Uruguaya de D. José Arechavaleta y Balparda [Santurce (España, 1838-Montevideo (Uruguay, 1912]. Algunas plantas están anotadas por Arechavaleta como especies nuevas -unas cuantas proceden de la localidad clásica- y todas ellas están identificadas por Arechavaleta o J. Hackel.

  13. El reinado del Cornificio y el exilio de las Musas. El filósofo educado en las Artes en la Antigüedad arcaica y en la Europa medieval hasta el siglo XII

    Directory of Open Access Journals (Sweden)

    Diego Pintado

    2016-12-01

    Full Text Available Este estudio describe y analiza el tránsito de un paradigma educativo (antiguo, clásico y medieval a un nuevo paradigma (el universitario, hacia el siglo XII. Se examina el origen y el desarrollo de un paradigma educativo y de formación que se remonta hasta la Grecia arcaica y que se mantuvo en vigencia en la Europa medieval hasta la creación de las universidades en el siglo XII. La tradición educativa de las artes liberales, conocida también como disciplinae cyclicae, es analizado como heredero directo de la tradición arcaica y pitagórica griega basada en la formación por las Musas. Se examinarán las similitudes y paralelismos entre las Musas y las Artes a la luz de la obra de Marciano Capela, De nuptis Philologiae et Mercuri. Luego se estudiará en modo conciso la figura del Cornificio, recreada por Juan de Salisbury en su Metalogicon, y se meditará sobre la relación de esta figura paradigmática y el contexto social, cultural, histórico, político y religioso que acaba dando lugar al nacimiento de los primeros estatutos universitarios. This paper treats the question of how the archaic and classical education paradigm is replaced by a new one based on institutionalization. It concerns about the origin and development of one education paradigm of schools, and the other paradigm, the institutional one, current and prevailing since the creation of the institution of university emerged about 12th century. The Liberal Arts education, also known as disciplinae cyclicae education, is analyzed according to the archaic and pithagoric greek tradition based on education by Muses. We will find similarities between Muses and Liberal Arts according to Martianus Capella’s work De nuptis Philologiae et Mercuri. Finally, we will observe this problem in John of Salisbury’ work Metalogicon and his central symbolic figure of the Cornificius.

  14. FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT BERWIRAUSAHA PADA SISWA KELAS XII SMK NEGERI 1 KANDEMAN KABUPATEN BATANG TAHUN 2011/2012

    Directory of Open Access Journals (Sweden)

    Fitriani Aprilia

    2012-10-01

    Full Text Available Interest in entrepreneurship is an encouragement, a sense of� interest and the availability of � the individual to conduct a business without fear of� the risk will occur. Secondary vocational schools are educational institutions that prepare students to be a human resources that ready to work and have capacity for work independently (entrepreneurial after graduate from this school. Factors originating from within the students and the factors that originate from outside is affecting interest in entrepreneurship. In this study population is 287 students. The samples are 74 students conducted by proportional random sampling. Independent variables exam- ined in this study were internal factors (X1 and external factors (X2. While the dependent variable is the interest in entrepreneurship (Y. The data was collected by questionnaires and documentation. The results of� descriptive research showed that the percentage of� interest in entrepreneurship is included in the high category, internal and external factors are included in either category. Partial internal factors have a significant influence of� 28.84%, while external factors also have a significant effect of� 7.34%. Variables simultaneously internal and external factors affect the interest of� entrepreneurship by 48.4%

  15. Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase.

    Science.gov (United States)

    Wu, Mingyi; Wen, Dandan; Gao, Na; Xiao, Chuang; Yang, Lian; Xu, Li; Lian, Wu; Peng, Wenlie; Jiang, Jianmin; Zhao, Jinhua

    2015-03-06

    Fucosylated chondroitin sulfate (FCS), a structurally unusual glycosaminoglycan, has distinct anticoagulant properties, and is an especially strong inhibitor of the intrinsic factor Xase (anti-Xase). To obtain a highly selective inhibitor of human Xase, we purified six native FCSs with various sulfation patterns, prepared a series of FCS derivatives, and then elucidated the relationship between the structures and the anticoagulant activities of FCSs. FCSs 1-3 containing higher Fuc2S4S exhibit stronger AT-dependent anti-IIa activities, whereas 4-6 containing more Fuc3S4S produce potent HCII-dependent anti-IIa activities. Saccharides containing a minimum of 6-8 trisaccharide units, free carboxyl groups, and full fucosylation of GlcA may be required for potent anti-Xase activity, and approximately six trisaccharide units and partial fucosylation of GlcA may contribute to potent HCII-dependent activity. Decreasing of the molecular weights markedly reduces their AT-dependent anti-IIa activities, and even eliminates human platelet and factor XII activation. Furthermore, in vitro and in vivo studies suggested that fractions of 6-12 kDa may be very promising compounds as putative selective intrinsic Xase inhibitors with antithrombotic action, but without the consequences of major bleeding and factor XII activation. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  16. Arboreas voces solis luneque loquentes: la visita de Alejandro Magno a los árboles del sol y de la luna en las crónicas del siglo XII

    Directory of Open Access Journals (Sweden)

    José Miguel De Toro Vidal

    2016-08-01

    Full Text Available El encuentro de Alejandro Magno con los árboles parlantes del Sol y de la Luna en un bosque sagrado de la India, constituye uno de los muchos episodios maravillosos de la leyenda alejandrina difundida en la Edad Media. El objetivo del presente artículo es estudiar el momento en que los cronistas deciden incorporar este pasaje en sus obras e indagar en las causas de esta decisión. Para ello se han revisado las crónicas universales del siglo XII y principios del XIII, cotejándolas con otras obras producidas en la época. Se aprecia que tanto la Historia Scholastica de Pedro Coméstor como los mapamundis contribuyeron a la aceptación del episodio. No obstante, la inclusión del pasaje en las crónicas no obedece tanto a la afirmación del encuentro con los árboles como un hecho cierto de la historia, sino al proyecto histórico-literario previsto por el autor de cada crónica.

  17. Manoel de Barros em terras estrangeiras: o livro das ignorãças, “uma didática da invenção”, Poema XII.

    Directory of Open Access Journals (Sweden)

    Tania Regina Vieira

    2010-04-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2009v2n24p97 Este artigo tem por objetivo relacionar as obras de Manoel de Barros traduzidas para o espanhol, o francês e o inglês, assim como apresentar o Poema XII, de “Uma Didática da Invenção”, parte de O Livro das Ignorãças, e sua tradução para essas línguas. Breve análise acompanha o poema e suas traduções, que dão mostras do estilo ímpar do poeta matogrossense, cujo universo poético é formado por coisas banais retiradas do cotidiano do Pantanal. Como fundamentação teórica, são trazidos os conceitos de patronagem, de André Lefevere, e de significância, agramaticalidade, leitura mimética e leitura semiótica, empregados por Michael Riffaterre e retomados por Mário Laranjeira. O exame da distribuição espacial da massa gráfica do poema, chamada de visilegibilidade por Laranjeira, inicia a análise, em que são mencionadas também as modalidades tradutórias de Francis Aubert.

  18. Los fines de la presencia de la Orden del Hospital en Castilla (Siglos XII y XIII = The objectives of the presence of the Order of the Hospital in Castile during the 12th and 13th Centuries

    Directory of Open Access Journals (Sweden)

    Carlos Barquero Goñi

    2015-06-01

    Full Text Available Las fuentes nos informan muy poco acerca de la suerte que tenían los recursos obtenidos por la Orden del Hospital de sus posesiones en la Corona de Castilla durante los siglos XII y XIII. Con toda seguridad lo primero en que debían utilizarse estas sumas era en el mantenimiento de todas las instalaciones y miembros de la Orden en Castilla y León. Lo que sobrase después de esto se habría de emplear en cuatro partidas distintas: aportaciones al convento central del Hospital en Oriente, actividad militar en la propia Corona de Castilla, desempeño de funciones asistenciales y propiamente hospitalarias, y soporte para algunas operaciones financieras.The sources provide us with scarce information on the use of resources obtained by the Order of the Hospital from its possessions in the Crown of Castile during the twelfth and thirteenth centuries. There is no doubt that this wealth was destined in the first place for the maintenance of all the facilities and members of the Order in Castile and Leon. What remained thereafter would be allocated to four different areas: Contributions to the central convent of the Hospital in the East; military activity within the Crown of Castile itself; coverage of welfare and specifically hospitaller functions; and support for certain financial operations.

  19. As parroquias do Porriño, Cans e Atios na documentación do mosteiro cisterciense de Santa María de Melón. Séculos XII e XIII

    Directory of Open Access Journals (Sweden)

    Gradín Fernández, Isis

    2011-12-01

    Full Text Available After the introduction and criteria of transcription, 31 papers are published from the twelfth and thirteenth centuries belonging to the Cistercian monastery of Santa Maria de Melon, specifically those that permit the reconstruction of old possessions, focusing on the current council of O Porriño -which was the monastery of San Miguel de Cans, absorbed by the cistercian monks of Melon. A paleographic and historical approximation of this documentation is done, which is complemented with the corresponding index of names and place names.

    [gl] Trala introducción e criterios de transcripción, edítanse 31 documentos dos séculos XII e XIII pertencentes ó mosteiro cisterciense de Santa María de Melón, concretamente aqueles que permiten reconstruír as antigas posesións –centradas sobre o actual concello de O Porriño- do que foi o mosteiro de San Miguel de Cans, absorvido polos monxes cistercienses de Melón. Faise unha aproximación paleográfica e histórica da documentación, que se complementa cos correspondentes índices onomásticos e toponímicos.

  20. The link between high-fat meals and postprandial activation of blood coagulation factor VII possibly involves kallikrein

    DEFF Research Database (Denmark)

    Larsen, L F; Marckmann, P; Bladbjerg, Else-Marie

    2000-01-01

    Contrary to low-fat meals, high-fat meals are known to cause postprandial factor VII (FVII) activation, but the mechanism is unknown. To study the postprandial FVII activation in detail, 18 young men consumed in randomized order high-fat or low-fat test meals. Fasting and non-fasting blood samples...... that triglyceride-rich lipoproteins may activate prokallikrein. Neither plasma triglycerides nor kallikrein and activated FVII were statistically associated. This may suggest that additional factors are involved in the postprandial FVII activation. No clear evidence for a role of tissue factor expression...... by monocytes, factor XII or insulin in postprandial FVII activation was observed. Tissue factor pathway inhibitor and prothrombin fragment 1+2, a marker of thrombin generation, were not affected postprandially after either the high-fat or the low-fat meals. Our findings indicate that triglyceride...

  1. Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease

    Directory of Open Access Journals (Sweden)

    Clarissa R. Nascimento

    2017-08-01

    Full Text Available During the course of Chagas disease, infectious forms of Trypanosoma cruzi are occasionally liberated from parasitized heart cells. Studies performed with tissue culture trypomastigotes (TCTs, Dm28c strain demonstrated that these parasites evoke neutrophil/CXCR2-dependent microvascular leakage by activating innate sentinel cells via toll-like receptor 2 (TLR2. Upon plasma extravasation, proteolytically derived kinins and C5a stimulate immunoprotective Th1 responses via cross-talk between bradykinin B2 receptors (B2Rs and C5aR. Awareness that TCTs invade cardiovascular cells in vitro via interdependent activation of B2R and endothelin receptors [endothelin A receptor (ETAR/endothelin B receptor (ETBR] led us to hypothesize that T. cruzi might reciprocally benefit from the formation of infection-associated edema via activation of kallikrein–kinin system (KKS. Using intravital microscopy, here we first examined the functional interplay between mast cells (MCs and the KKS by topically exposing the hamster cheek pouch (HCP tissues to dextran sulfate (DXS, a potent “contact” activator of the KKS. Surprisingly, although DXS was inert for at least 30 min, a subtle MC-driven leakage resulted in factor XII (FXII-dependent activation of the KKS, which then amplified inflammation via generation of bradykinin (BK. Guided by this mechanistic insight, we next exposed TCTs to “leaky” HCP—forged by low dose histamine application—and found that the proinflammatory phenotype of TCTs was boosted by BK generated via the MC/KKS pathway. Measurements of footpad edema in MC-deficient mice linked TCT-evoked inflammation to MC degranulation (upstream and FXII-mediated generation of BK (downstream. We then inoculated TCTs intracardiacally in mice and found a striking decrease of parasite DNA (quantitative polymerase chain reaction; 3 d.p.i. in the heart of MC-deficient mutant mice. Moreover, the intracardiac parasite load was significantly reduced in WT

  2. Puerarin Attenuates Ovalbumin-Induced Lung Inflammation and Hemostatic Unbalance in Rat Asthma Model

    Directory of Open Access Journals (Sweden)

    Feng Dong

    2014-01-01

    Full Text Available Aim. We aimed to investigate and evaluate the preventive activity of puerarin on the ovalbumin-induced asthma rat model. Materials and Methods. Male Wistar rats were sensitized intraperitoneally on days 0, 7, and 14 and challenged to ovalbumin intratracheally on day 21. Groups of sensitized rats were treated randomly either with placebo, puerarin, dexamethasone, or puerarin combined with dexamethasone, from days 15 to 20. Inflammatory markers, including cell counts in bronchoalveolar lavage fluid (BALF, inflammatory cytokines, histopathology, and coagulation parameters, such as coagulation tests and the activity of coagulation factors, were analyzed. Results. Puerarin significantly inhibited the recruitment of inflammatory cells in BALF and lung tissue. At the same time, the release of IL-4, IL-10, and IFN-γ in serum and the expression of mRNAs in lung tissue homogenate were changed by puerarin. Administration of puerarin also effectively rectified the coagulation disorder in asthmatic rats, such as prothrombin time (PT (P<0.01, thrombin time (TT (P<0.05, fibrinogen (FIB (P<0.01,the activity of factor II (FII (P<0.01, the activity of factor V (FV (P<0.05, the activity of factor VII (FVII (P<0.05, the activity of factor X (FX (P<0.05, the activity of factor VIII (FVIII (P<0.01, the activity of factor IX (FIX (P<0.05, and the activity of factor XII (FXII (P<0.05. Conclusions. Our results provide a clue that puerarin was useful for the preventive of allergic airway disease in rodents.

  3. HUBUNGAN STATUS SOSIAL EKONOMI ORANG TUA DAN PRESTASI BELAJAR MATA PELAJARAN KEJURUAN DENGAN MINAT MELANJUTKAN KE PERGURUAN TINGGI SISWA KELAS XII PROGRAM KEAHLIAN TEKNIK KENDARAN RINGAN SMK MUHAMMADIYAH 1 BAMBANGLIPURO BANTUL TAHUN PELAJARAN2013/2014

    Directory of Open Access Journals (Sweden)

    Herri Indra Lesmana

    2014-06-01

    Full Text Available The purpose of the study; (1 to determine whether there is a positive relationship between socio economic standing of parents with interest to go to college; (2 to determine whether there is a positive relationship between learning achievement vocational subjects with with interest to go to college; (3 to determine whether there is a positive relationship between socio economic standing and learning achievement vocational subjects with interest to go to college. This research was conducted at Muhammadiyah 1 Vocational school of Bambanglipuro, Bantul academic year 2013/2014. The population in this study were all students of class XII Light Vehicle Enginering totaling 91 students and this study used a sampling saturated or study populations so that the entire population were sampled. This research is correlational and ex post facto categorized. Questionnaire data collection techniques and documentation of learning achivement vocational subject. The validity of the items were obtained from the product moment correlation.  About the reliability of the formula obtained by alpha and declared reliable. Before the data were analyzed first tested the prerequisite analysis is normality test, multicollinearity, and linearity test. Analysis using simple regression analysis and multiple regression analysis. From the analysis of the results obtained the following results: (1 There is a positive and significant relationship between socio economic standing of parents (X1 with interest to go to college (Y; (2 There is a positive and significant relationship between learning achievement vocational subjects (X2 with interest to go to college (Y; (3 There is a positive and significant relationship between socio economic standing of parents (X1 and learning achivement vocational subjects (X2 together with interest to go to college (Y.

  4. The XII Century Towers, a Benchmark of the Rome Countryside almost Cancelled: the Safeguard Plan by Low Cost Uav and Terrestrial Dsm Photogrammetry Surveying and 3d Web GIS Applications

    Science.gov (United States)

    Barelli, L.; Paolini, P.; Forti, G.

    2017-11-01

    "Giving a bird-fly look at the Rome countryside, throughout the Middle Age central period, it would show as if the multiple city towers has been widely spread around the territory" on a radial range of maximum thirty kilometers far from the Capitol Hill center (Carocci and Vendittelli, 2004). This is the consequence of the phenomenon identified with the "Incasalamento" neologism, described in depth in the following paper, intended as the general process of expansion of the urban society interests outside the downtown limits, started from the half of the XII and developed through all the XIII century, slowing down and ending in the following years. From the XIX century till today the architectural finds of this reality have raised the interest of many national and international scientists, which aimed to study and catalog them all to create a complete framework that, cause of its extension, didn't allow yet attempting any element by element detailed analysis. From the described situation has started our plan of intervention, we will apply integrated survey methods and technologies of terrestrial and UAV near stereo-photogrammetry, by the use of low cost drones, more than action cameras and reflex on extensible rods, integrated and referenced with GPS and topographic survey. In the final project we intend to produce some 3D scaled and textured surface models of any artifact (almost two hundreds were firstly observed still standing), to singularly study the dimensions and structure, to analyze the building materials and details and to formulate an hypothesis about any function, based even on the position along the territory. These models, successively georeferenced, will be imported into a 2D and 3D WebGIS and organized in layers made visible on basemaps of reference, as much as on historical maps.

  5. Risk factors for indications of intraoperative blood transfusion among patients undergoing surgical treatment for colorectal adenocarcinoma.

    Science.gov (United States)

    Gonçalves, Iara; Linhares, Marcelo; Bordin, Jose; Matos, Delcio

    2009-01-01

    Identification of risk factors for requiring transfusions during surgery for colorectal cancer may lead to preventive actions or alternative measures, towards decreasing the use of blood components in these procedures, and also rationalization of resources use in hemotherapy services. This was a retrospective case-control study using data from 383 patients who were treated surgically for colorectal adenocarcinoma at 'Fundação Pio XII', in Barretos-SP, Brazil, between 1999 and 2003. To recognize significant risk factors for requiring intraoperative blood transfusion in colorectal cancer surgical procedures. Univariate analyses were performed using Fisher's exact test or the chi-squared test for dichotomous variables and Student's t test for continuous variables, followed by multivariate analysis using multiple logistic regression. In the univariate analyses, height (P = 0.06), glycemia (P = 0.05), previous abdominal or pelvic surgery (P = 0.031), abdominoperineal surgery (Pblood transfusion.

  6. Innovación y ruptura en la métrica de la poesía en al-Maqāmāt al-Luzūmiyya de al-Saraqusṭī (s. VI/XII

    Directory of Open Access Journals (Sweden)

    Ferrando, Ignacio

    2016-06-01

    Full Text Available Al-Maqāmāt al-Luzūmiyya, a collection of 50 picaresque-like stories couched in rhymed prose by Abū l-Ṭāhir al-Saraqusṭī in al-Andalus in the VI/XIIth century, were considered by Western scholars, up until the eighties of XXth century, as highly rhetorical pieces with a negligible and irrelevant content. However, some contemporary scholars argued that they contain some degree of social and political criticism, as they constitute a fictional domain in which subversion and irony play a fundamental role. In this paper, we cast some light on the particular use of metrical patterns in Al-Maqāmāt al-Luzūmiyya, which should be considered another subversion field: a poetical rhythm that avoids the most usual Arabic metrical patterns, contributing to provide the maqāma a flavor of the countergenre.Al-Maqāmāt al-Luzūmiyya, la colección de 50 relatos de corte picaresco escritos en una exigente prosa rimada por Abū l-Ṭāhir al-Saraqusṭī en al-Andalus en el siglo VI/XII, han sido consideradas por los críticos occidentales como piezas de alta retórica y de virtuosismo lingüístico en las que el contenido es prácticamente irrelevante. Sin embargo, a partir de los años 80 del siglo pasado, algunos investigadores han tratado de incidir en el hecho de que esta obra contiene cierto grado de crítica social y política, puesto que constituye un espacio ficticio en el que la subversión y la ironía desempeñan un papel fundamental. En este trabajo vamos a tratar de arrojar luz sobre el uso particular de los esquemas métricos por parte de al-Saraqusṭī, tratando de mostrar que los metros constituyen otro más de los ámbitos de subversión tan caros al autor. De hecho, el uso de ritmos “invertidos” o contrarios a los más habituales de la poesía clásica contribuye a darle a la maqāma ese aire de anti género que la puebla.

  7. Al-Ḏajīra al-saniyya: una fuente relevante para el siglo XII en la Península Ibérica

    Directory of Open Access Journals (Sweden)

    Ramírez-del-Río, José

    2012-06-01

    Full Text Available The work al-Dhakhīra al-saniyya fī ta’rīkh al-dawla al-marīniyya records the history of the Marīnid dynasty, including a number of references to other Islamic regions like Egypt, Syria and al-Andalus. The authorship of this chronicle has not yet been solved. The aim of this paper is to provide the most relevant information on the issue. Alongside with other type of information concerning al-Andalus, this paper focuses on that which concerns the territory conquered by the Kingdom of Castile throughout the 13th century, and which so far has been mostly disregarded. It undoubtedly contributes to improve our knowledge of the period, especially as regards both the destiny of the conquered Muslim populations and the chronology of the conquest. We will also focus here on the political leaders of al-Andalus and Maghreb, their reactions towards the Christian conquests, ranging from utter resistance to conversion, and the importance this group attached to fighting the Christians, as a key factor of the political legitimacy of the Banū Marīn to guide the Islamic community, a point that greatly concerns the author of the present chronicle.La obra al-Ḏajīra al-saniyya fī ta’rīj aldawla al-marīniyya, que aborda la historia de los Banū Marīn, incluye una serie de noticias referentes a otras tierras de la Dār al-Islam, como Egipto, Siria o al-Andalus. La autoría de la misma no ha sido determinada, por lo que señalaremos las noticias más destacadas sobre este asunto. De la información que ofrece esta obra acerca de al-Andalus, este artículo se centra en el análisis de los fragmentos relativos a los territorios conquistados por Castilla durante el s. XIII, que no había sido aprovechada hasta el momento, y que contribuye a ampliar nuestro conocimiento acerca de este período histórico, muy especialmente por lo que respecta a la suerte que corrieron las poblaciones musulmanas y a la cronología de la conquista. Abordamos las actitudes

  8. Ressenya a Delle Donne, Fulvio & Torró, Jaume (eds. L’immagine di Alfonso il Magnanimo tra letteratura e storia, tra Corona d’Aragona e Italia - La imatge d’Algons el Magnànim en la literatura i la Historiografia entre la Corona d’Aragó i Itàlia, Florència, SISMEL -Edizioni del Galluzzo , 2016, XII + 300 p. ISBN: 978-88-8450-691-7

    Directory of Open Access Journals (Sweden)

    Marta Marfany Simó

    2016-12-01

    Full Text Available Review to Delle Donne, Fulvio & Torró, Jaume (eds. L’immagine di Alfonso il Magnanimo tra letteratura e storia, tra Corona d’Aragona e Italia - La imatge d’Algons el Magnànim en la literatura i la Historiografia entre la Corona d’Aragó i Itàlia, Firenze, SISMEL -Edizioni del Galluzzo , 2016, XII + 300 p. ISBN: 978-88-8450-691-7

  9. DNA Barcoding for Identification of "Candidatus Phytoplasmas" Using a Fragment of the Elongation Factor Tu Gene

    DEFF Research Database (Denmark)

    Makarova, Olga; Contaldo, Nicoletta; Paltrinieri, Samanta

    2012-01-01

    Background Phytoplasmas are bacterial phytopathogens responsible for significant losses in agricultural production worldwide. Several molecular markers are available for identification of groups or strains of phytoplasmas. However, they often cannot be used for identification of phytoplasmas from...... different groups simultaneously or are too long for routine diagnostics. DNA barcoding recently emerged as a convenient tool for species identification. Here, the development of a universal DNA barcode based on the elongation factor Tu (tuf) gene for phytoplasma identification is reported. Methodology....../Principal Findings We designed a new set of primers and amplified a 420–444 bp fragment of tuf from all 91 phytoplasmas strains tested (16S rRNA groups -I through -VII, -IX through -XII, -XV, and -XX). Comparison of NJ trees constructed from the tuf barcode and a 1.2 kbp fragment of the 16S ribosomal gene revealed...

  10. Planck 2013 results. XII. Diffuse component separation

    CERN Document Server

    Ade, P A R; Armitage-Caplan, C; Arnaud, M; Ashdown, M; Atrio-Barandela, F; Aumont, J; Baccigalupi, C; Banday, A J; Barreiro, R B; Bartlett, J G; Battaner, E; Benabed, K; Benoît, A; Benoit-Lévy, A; Bernard, J -P; Bersanelli, M; Bielewicz, P; Bobin, J; Bock, J J; Bonaldi, A; Bonavera, L; Bond, J R; Borrill, J; Bouchet, F R; Boulanger, F; Bridges, M; Bucher, M; Burigana, C; Butler, R C; Cardoso, J -F; Catalano, A; Challinor, A; Chamballu, A; Chary, R -R; Chen, X; Chiang, L -Y; Chiang, H C; Christensen, P R; Church, S; Clements, D L; Colombi, S; Colombo, L P L; Couchot, F; Coulais, A; Crill, B P; Cruz, M; Curto, A; Cuttaia, F; Danese, L; Davies, R D; Davis, R J; de Bernardis, P; de Rosa, A; de Zotti, G; Delabrouille, J; Delouis, J -M; Désert, F -X; Dickinson, C; Diego, J M; Dole, H; Donzelli, S; Doré, O; Douspis, M; Dunkley, J; Dupac, X; Efstathiou, G; Enßlin, T A; Eriksen, H K; Falgarone, E; Finelli, F; Forni, O; Frailis, M; Fraisse, A A; Franceschi, E; Galeotta, S; Ganga, K; Giard, M; Giardino, G; Giraud-Héraud, Y; González-Nuevo, J; Górski, K M; Gratton, S; Gregorio, A; Gruppuso, A; Hansen, F K; Hanson, D; Harrison, D; Helou, G; Henrot-Versillé, S; Hernández-Monteagudo, C; Herranz, D; Hildebrandt, S R; Hivon, E; Hobson, M; Holmes, W A; Hornstrup, A; Hovest, W; Huey, G; Huffenberger, K M; Jaffe, T R; Jaffe, A H; Jewell, J; Jones, W C; Juvela, M; Keihänen, E; Keskitalo, R; Kisner, T S; Kneissl, R; Knoche, J; Knox, L; Kunz, M; Kurki-Suonio, H; Lagache, G; Lähteenmäki, A; Lamarre, J -M; Lasenby, A; Laureijs, R J; Lawrence, C R; Jeune, M Le; Leach, S; Leahy, J P; Leonardi, R; Lesgourgues, J; Liguori, M; Lilje, P B; Linden-Vørnle, M; López-Caniego, M; Lubin, P M; Macías-Pérez, J F; Maffei, B; Maino, D; Mandolesi, N; Marcos-Caballero, A; Maris, M; Marshall, D J; Martin, P G; Martínez-González, E; Masi, S; Matarrese, S; Matthai, F; Mazzotta, P; Meinhold, P R; Melchiorri, A; Mendes, L; Mennella, A; Migliaccio, M; Mikkelsen, K; Mitra, S; Miville-Deschênes, M -A; Moneti, A; Montier, L; Morgante, G; Mortlock, D; Moss, A; Munshi, D; Naselsky, P; Nati, F; Natoli, P; Netterfield, C B; Nørgaard-Nielsen, H U; Noviello, F; Novikov, D; Novikov, I; O'Dwyer, I J; Osborne, S; Oxborrow, C A; Paci, F; Pagano, L; Pajot, F; Paladini, R; Paoletti, D; Partridge, B; Pasian, F; Patanchon, G; Pearson, T J; Perdereau, O; Perotto, L; Perrotta, F; Pettorino, V; Piacentini, F; Piat, M; Pierpaoli, E; Pietrobon, D; Plaszczynski, S; Platania, P; Pointecouteau, E; Polenta, G; Ponthieu, N; Popa, L; Poutanen, T; Pratt, G W; Prézeau, G; Prunet, S; Puget, J -L; Rachen, J P; Reach, W T; Rebolo, R; Reinecke, M; Remazeilles, M; Renault, C; Renzi, A; Ricciardi, S; Riller, T; Ristorcelli, I; Rocha, G; Rosset, C; Roudier, G; Rowan-Robinson, M; Rubiño-Martín, J A; Rusholme, B; Salerno, E; Sandri, M; Santos, D; Savini, G; Schiavon, F; Scott, D; Seiffert, M D; Shellard, E P S; Spencer, L D; Starck, J -L; Stompor, R; Sudiwala, R; Sunyaev, R; Sureau, F; Sutton, D; Suur-Uski, A -S; Sygnet, J -F; Tauber, J A; Tavagnacco, D; Terenzi, L; Toffolatti, L; Tomasi, M; Tristram, M; Tucci, M; Tuovinen, J; Türler, M; Umana, G; Valenziano, L; Valiviita, J; Van Tent, B; Varis, J; Viel, M; Vielva, P; Villa, F; Vittorio, N; Wade, L A; Wandelt, B D; Wehus, I K; Wilkinson, A; Xia, J -Q; Yvon, D; Zacchei, A; Zonca, A

    2014-01-01

    Planck has produced detailed all-sky observations over nine frequency bands between 30 and 857 GHz. These observations allow robust reconstruction of the primordial cosmic microwave background (CMB) temperature fluctuations over nearly the full sky, as well as new constraints on Galactic foregrounds. This paper describes the component separation framework adopted by Planck. We test four foreground-cleaned CMB maps derived using qualitatively different component separation algorithms. The quality of our reconstructions is evaluated through detailed simulations and internal comparisons, and shown through various tests to be internally consistent and robust for CMB power spectrum and cosmological parameter estimation up to l = 2000. The parameter constraints on LambdaCDM cosmologies derived from these maps are consistent with those presented in the cross-spectrum based Planck likelihood analysis. We choose two of the CMB maps for specific scientific goals. We also present maps and frequency spectra of the Galact...

  11. Genetic programming theory and practice XII

    CERN Document Server

    Riolo, Rick; Kotanchek, Mark

    2015-01-01

    These contributions, written by the foremost international researchers and practitioners of Genetic Programming (GP), explore the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. Topics in this volume include: gene expression regulation, novel genetic models for glaucoma, inheritable epigenetics, combinators in genetic programming, sequential symbolic regression, system dynamics, sliding window symbolic regression, large feature problems, alignment in the error space, HUMIE winners, Boolean multiplexer funct

  12. Defects and diffusion in semiconductors XII

    CERN Document Server

    Fisher, David J

    2010-01-01

    This twelfth volume in the series covering the latest results in the field includes abstracts of papers which have appeared since the publication of Annual Retrospective XI (Volume 282). As well as the 565 semiconductor-related abstracts, the issue includes - in line with the policy of including original papers on all of the major material groups: ""Study of Conduction Mechanism in Amorphous Se85-xTe15Bix Thin Films"" (A.Sharma and P.B.Barman), ""Structure and Optical Properties of Magnetron-Sputtered SiOx Layers with Silicon Nanoparticles"" (L.Khomenkova, N.Korsunska, T.Stara, Y.Goldstein, J.

  13. Planck 2013 results. XII. Component separation

    DEFF Research Database (Denmark)

    Planck Collaboration,; Ade, P. A. R.; Aghanim, N.

    2013-01-01

    Planck has produced detailed all-sky observations over nine frequency bands between 30 and 857 GHz. These observations allow robust reconstruction of the primordial cosmic microwave background (CMB) temperature fluctuations over nearly the full sky, as well as new constraints on Galactic foregrou...

  14. Degenerate stars. XII - Recognition of hot nondegenerates

    Science.gov (United States)

    Greenstein, J. L.

    1980-12-01

    Fifty-one newly observed degenerate stars and 14 nondegenerates include 13 faint red stars, most of which do not show any lines except DF, Gr 554. Hot subdwarfs and an X-ray source are discussed along with the problem of low-resolution spectroscopic classification of dense hot stars. The multichannel spectrum of the carbon-rich magnetic star LP 790-29 is examined by fitting the undisturbed parts of the spectrum to a black body of 7625 K by the least squares method; the Swan bands absorb 600 A of the spectrum assuming that the blocked radiation is redistributed in the observed region.

  15. Planck 2013 results. XII. Diffuse component separation

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.

    2014-01-01

    of primordial non-Gaussianity and statistical isotropy, the integrated Sachs-Wolfe effect, gravitational lensing, and searches for topological defects. We test four foreground-cleaned CMB maps derived using qualitatively different component separation algorithms. The quality of our reconstructions is evaluated...

  16. Complex Light and Optical Forces XII

    DEFF Research Database (Denmark)

    With 2,000 papers and presentations, SPIE OPTO 2018 is the most important optoelectronics conference you can attend in 2018. Topics include on silicon photonics, photonic crystals, optoelectronics, semiconductor lasers, quantum dots, and nanophotonics. This conference addresses the latest...

  17. Kuni 11. XII oli Tallinna Linnagaleriis...

    Index Scriptorium Estoniae

    2005-01-01

    Valie Export Society (Kadi Estland, Mari Laanemets, Killu Sukmit) väljapanek "Streik ei ole horoskoop!" - dokumentatsioon, kus üksteisele saadetud e-kirjades avatakse naiskunstnike rühmituse eesmärk ja praegune olukord, peatutakse Eesti kunstielu võimuküsimustel

  18. Progress in ultrafast intense laser science XII

    CERN Document Server

    Roso, Luis; Li, Ruxin; Mathur, Deepak; Normand, Didier

    2015-01-01

    This  volume covers a broad range of topics focusing on atoms, molecules, and clusters interacting in intense laser field, laser induced filamentation, and laser plasma interaction and application. The PUILS series delivers up-to-date reviews of progress in Ultrafast Intense Laser Science, a newly emerging interdisciplinary research field spanning atomic and molecular physics, molecular science, and optical science, which has been stimulated by the recent developments in ultrafast laser technologies. Each volume compiles peer-reviewed articles authored by researchers at the forefront of each their own subfields of UILS. Every chapter opens with an overview of the topics to be discussed, so that researchers unfamiliar to the subfield, as well as graduate students, can grasp the importance and attractions of the research topic at hand; these are followed by reports of cutting-edge discoveries. .

  19. Synthesis of human pancreatic growth hormone-releasing factor and two omission analogs by segment-coupling method in aqueous solution

    Energy Technology Data Exchange (ETDEWEB)

    Blake, J.; Westphal, M.; Li, C.H. (Laboratory of Molecular Endocrinology, University of California, San Francisco, USA)

    1984-01-01

    The human growth hormone-releasing factor (GRF) peptides (GlyS/sup 15/)-GRF-(1-15) (IV), trifluoroacetyl-GRF-(20-44) (VI), trifluoroacetyl-GRF-(18-44) (VIII), and trifluoroacetyl-GRF-(16-44) (X) were synthesized by the solidphase method. Each of the peptides was reacted with citraconic anhydride and the trifluoroacetyl group was removed by reaction with 10% hydrazine in water. The citraconylated GRF-(1-15) peptide was coupled to the (20-44), (18-44) or (16-44) peptides by reaction with silver nitrate/N-hydroxysuccinimide to give GRF-(1-15)-(20-44) (XII), GRF-(1-15)-(18-44) (XIII), or GRF-(1-44), respectively. GRF-(1-44) was shown to stimulate the release of rat growth hormone from rat pituitary cells with an ED/sub 50/=8.8 x 10/sup -11/M. Peptides XII and XIII were inactive, either as agonists or as antagonists of the action of GRF-(1-44).

  20. INFLUENCE OF PARENTS' SOCIO-ECONOMIC STATUS AND VOCATIONAL LEARNING MOTIVATION TO LEARNING ACHIEVEMENT IN THE LESSON OF CHASSIS AND POWER TRANSDUCTOR FOR XII GRADE STUDENTS OF LIGHT VIHICLE ENGINEERING DEPARTMENT OF SMK PIRI 1 YOGYAKARTA IN ACADEMIC YEAR 2013/2014

    Directory of Open Access Journals (Sweden)

    Indra Tri Setyawan

    2014-06-01

    Full Text Available The purpose of the study is to find the influence of parents’ socio-economic status and vocational learning motivation to learning achievement in the lesson of chassis and power transductor for XII grade students of SMK PIRI 1 Yogyakarta in the academic year 2013/2014. This research includes ex-post facto research conducted on the population 129 students with the sample 98 students. Data collection techniques in this research uses questionnaire instrument techniques for variable of parents’ socio-economic status and vocational learning motivation whereas documentation instrument techniques uses for variable of learning achievement the lesson of chassis and power transductor. Questionnaire was tested on 25 respondents. Data analysis techniques uses partial correlation analysis and regression analysis were preceded by prerequisite test that are normality test, linearity and multikolonieritas. The results of the data analysis is (1 parents’ socio-economic status (X1 influential positive and significant on learning achievement in the lesson of chassis and power transductor, (2 vocational learning motivation (X2 influential positive and significant on learning achievement in the lesson of chassis and power transductor, (3 parents’ socio-economic status (X1 and vocational learning motivation (X2 are jointly have positive and significant effect on learning achievement in the lesson of chassis and power transductor. Positive means that the higher the value of X1 and X2, the higher the value of Y, and vice versa. Thus, the socio-economic status of parents and the motivation to study vocational subjects affecting learning achievement the lesson of chassis and power transductor XII grade students of SMK PIRI 1 Yogyakarta in the academic year 2013/2014.

  1. Βιβλιοκρισία του: Martin da Canal, Les Estoires de Venise, αγγλική μετάφραση, εισαγωγή και σχόλια LAURA K. MORREALE [Archivio del Litorale Adriatico XII], Padova 2009

    Directory of Open Access Journals (Sweden)

    Μαρίνα ΚΟΥΜΑΝΟΥΔΗ

    2012-03-01

    Full Text Available Βιβλιοκρισία του: Martin da Canal, Les Estoires de Venise, αγγλική μετάφραση, εισαγωγή και σχόλια LAURA K. MORREALE [Archivio del Litorale Adriatico XII], Padova 2009, σσ. xxii + 175 [ΙSBN 978-88-8098-267-8].

  2. Risk Factors

    Science.gov (United States)

    ... cells do not invade nearby tissues or spread. Risk Factors Key Points Factors That are Known to ... chemicals . Factors That are Known to Increase the Risk of Cancer Cigarette Smoking and Tobacco Use Tobacco ...

  3. Anionic polymerization of acrylates. XII. Polymerization of methyl methacrylate and tert-butyl acrylate initiated with alkyllithiums or methyl 2-lithioisobutyrate in the presence of lithium tert-butoxide

    Czech Academy of Sciences Publication Activity Database

    Vlček, Petr; Otoupalová, Jaroslava; Janata, Miroslav; Látalová, Petra; Masař, Bohumil; Toman, Luděk

    2002-01-01

    Roč. 43, č. 25 (2002), s. 7179-7184 ISSN 0032-3861 R&D Projects: GA ČR GA203/01/0513; GA MŠk OC P1.10 Institutional research plan: CEZ:AV0Z4050913 Keywords : ligated anionic polymerization * (meth)acrylates * lithium tert-butoxide Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.838, year: 2002

  4. The dam in Garganta del Ciervo, 12th century (Segura de la Sierra, Jaén, España: contributions to Andalusian hydraulic engineering | La presa de la Garganta del Ciervo, s. XII (Segura de la Sierra, Jaén, España: aportaciones a la ingeniería hidráulica andalusí

    Directory of Open Access Journals (Sweden)

    Vicente Salvatierra Cuenca

    2016-12-01

    Full Text Available In this text we analyze a remarkable Islamic dam located in Sierra de Segura, dated from the 12th century. The size of the dam, 11 m high and 9 m thick, its location in a mostly flat area, the technique used to build it, the reservoir that it created, etc. makes dams a very singular element among the irrigation architecture in Al-Andalus. In addition to describing the dam, we also intend to discuss to which point the purpose of this structure was truly different from what was usually done at that time, and, therefore, if it means both a technological and social change, or if its configuration hid other objectives. | En este texto analizamos una notable presa islámica localizada en la Sierra de Segura, fechada en el siglo XII. Su envergadura, 11 m de altura y 9 m de grosor, su situación en una zona sustancialmente llana, su técnica de fabricación, el pantano que generaba, etc. la convierten en principio en un elemento muy atípico dentro de la arquitectura de regadío andalusí. Además de realizar su descripción, nos proponemos discutir hasta qué punto la finalidad de esta estructura era realmente diferente a lo que se hacía en la época, y si supone por tanto un cambio tecnológico y social. O si su configuración escondía otros objetivos.

  5. Robust factorization

    DEFF Research Database (Denmark)

    Aanæs, Henrik; Fisker, Rune; Åström, Kalle

    2002-01-01

    Factorization algorithms for recovering structure and motion from an image stream have many advantages, but they usually require a set of well-tracked features. Such a set is in generally not available in practical applications. There is thus a need for making factorization algorithms deal effect...

  6. Organizational factors

    International Nuclear Information System (INIS)

    Holy, J.

    1999-12-01

    The following organizational factors are considered with respect to the human factor and operating safety of nuclear power plants: external influences; objectives and strategy; positions and ways of management; allocation of resources; working with human resources; operators' training; coordination of work; knowledge of organization and management; proceduralization of the topic; labour organizing culture; self-improvement system; and communication. (P.A.)

  7. El factoring

    Directory of Open Access Journals (Sweden)

    Alberto Rosenthal

    1988-04-01

    Full Text Available RESUMEN El artículo  presenta, una conceptualización general de lo que es el factoring, el origen del mismo, su evolución y hace una clasificación de los distintos tipos de factoring.

  8. El factoring

    Directory of Open Access Journals (Sweden)

    Alberto Rosenthal

    2015-04-01

    Full Text Available RESUMEN Se presenta la segunda parte del artículo aparecido en  el número 6 de la revista EAN. Su contenido es complementario a lo expuesto en dicho número, en está aparecen las ventajas del factoring, conveniencias, limitaciones así como la forma  de efectuar un factor en Colombia,  su necesidad, incidencia económica, etc.

  9. Quality factors

    International Nuclear Information System (INIS)

    Kerr, G.D.

    1986-01-01

    The quality factor, Q, is a dimensionless modifier used in converting absorbed dose, expressed in rads (or grays), to dose equivalent, expressed in rems (or seiverts). The dose equivalent is used in radiation protection to account for the biological effectiveness of different kinds of radiation. The quality factor is related to both the linear energy transfer (LET) and relative biological effectiveness (RBE). The RBE's obtained from biological experiments depend in a complex way on the observed biological effect, the specific test organism, and the experimental conditions. Judgement is involved, therefore, in the choice of the quality factor. Questions regarding the adequacy of current Q values for neutrons were raised first in a 1980 statement by the National Council on Radiation Protection (NCRP) and later in a 1985 statement by the International Commission on Radiological Protection (ICRP). In 1980, the NCRP alerted the technical community to possible future increases between a factor of three and ten in the Q for neutrons, and in 1985, the ICRP suggested an increase by a factor of two in Q for neutrons. Both the ICRP and NRCP are now recommending essentially the same guidance with regard to Q for neutrons: an increase by a factor of two. The Q for neutrons is based on a large, albeit unfocused, body of experimental data. In spite of the lack of focus, the data supporting a change in the neutron quality factor are substantial. However, the proposed doubling of Q for neutrons is clouded by other issues regarding its application. 33 refs., 4 figs., 6 tabs

  10. Risk factors

    International Nuclear Information System (INIS)

    Dennery, M.; Dupont, M.A.

    2007-01-01

    This article deals with the development of risk management in the gas sector business: why a risk factor legal mention must precede any published financial information? Do gas companies have to face new risks? Is there specific risks bound to gas activities? Why companies want to master their risks? Is it mandatory or just a new habit? Do they expect a real benefit in return? These are the risk management questions that are analyzed in this article which is based on the public communication of 15 gas companies randomly selected over the world. The information comes from their annual reports or from documents available on their web sites. The intention of this document is not to be exhaustive or to make statistics but only to shade light on the risk factors of the gas sector. (J.S.)

  11. Organizational factors

    International Nuclear Information System (INIS)

    Wahlstroem, B.; Kettunen, J.

    2005-01-01

    The goal of this lecture is to give an overview of important concepts connected to organisational factors and to provide an understanding of mechanisms by which they can contribute to safe or unsafe behaviour of people. The lecture gives examples of ways to organise work, organisational deficiencies and good practices applied in safety oriented organisations. The lecture also gives an introduction to international work and Finnish national regulation connected to organisation and management. (orig.)

  12. Factor analysis

    CERN Document Server

    Gorsuch, Richard L

    2013-01-01

    Comprehensive and comprehensible, this classic covers the basic and advanced topics essential for using factor analysis as a scientific tool in psychology, education, sociology, and related areas. Emphasizing the usefulness of the techniques, it presents sufficient mathematical background for understanding and sufficient discussion of applications for effective use. This includes not only theory but also the empirical evaluations of the importance of mathematical distinctions for applied scientific analysis.

  13. 7. XII avati rahvusraamatukogu VI korruse näitusesaalis...

    Index Scriptorium Estoniae

    2005-01-01

    Hispaania Graafiliste Kunstide Akadeemia (Calcografia Nacional) koostatud ja Hispaania Suursaatkonna vahendatud näitus "Goya : portreteeritud südametunnistus". Väljas on 20 suureformaadilist digitaalpilti Francisco de Goya gravüüridest. Enne näituse avamist pidas Ramon de Villanueva loengu "Selgitusi Goya loomingu mõistmiseks"

  14. Mid-Infrared Optoelectronics: Materials and Devices. MIOMD-XII

    Science.gov (United States)

    2014-10-01

    University, 6100 Main Street, Houston, TX 77005‐1827, USA 3Dipartimento Interateneo di Fisica , Università e Politecnico di Bari Via Amendola 173, I‐70126, Bari...Lancaster University, Lancaster, LA1 4YB, UK 2School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD, UK 3Dipartimento di Fisica

  15. Parnassiana nova : XII. Kritische Revision der Gattung Parnassius (Fortsetzung 8)

    NARCIS (Netherlands)

    Eisner, C.

    1957-01-01

    Bevor ich mit der Bearbeitung des dritten genus der Parnassiinae beginne, muss ich noch einmal einen Rückblick auf die bereits erfolgte Revision werfen. Ich habe schon früher erwähnt, dass meine Publikationen durch Aufführung aller in meiner Sammlung befindlichen Exemplare einen wissenschaftlichen

  16. NPP safety and personnel training. XII International conference. Abstracts

    International Nuclear Information System (INIS)

    2011-01-01

    The 12th International conference NPP Safety and Personnel Training took place in Obninsk, October 4-7, 2011. The issues of nuclear technologies safety are considered.The problems of life-cycle management of nuclear facilities are discussed. The criteria of assessment of physical protection systems of nuclear facilities are presented [ru

  17. Division X, XII / Commission 40, 41 / Working Group Radio Astronomy

    NARCIS (Netherlands)

    Kellermann, Kenneth; Orchiston, Wayne; Davies, Rod; Gurvits, Leonid; Ishiguro, Masato; Lequeux, James; Swarup, Govind; Wall, Jasper; Wielebinski, Richard; van Woerden, Hugo

    The IAU Working Group on Historical Radio Astronomy (WGHRA) was formed at the 2003 General Assembly of the IAU as a Joint Working Group of Commissions 40 (Radio Astronomy) and 41 (History of Astronomy), in order to: a) assemble a master list of surviving historically-significant radio telescopes and

  18. Toxicity of inhaled 91YCl3 in Beagle dogs. XII

    International Nuclear Information System (INIS)

    Muggenburg, B.A.; Rebar, A.H.; Boecker, B.B.; Jones, R.K.; McClellan, R.O.; Pickrell, J.A.

    1978-01-01

    Studies on the metabolism, dosimetry and effects of inhaled 91 YCl 3 in Beagle dogs are being continued to provide information that will aid in assessing the biological consequences of nuclear accidents in which 91 Y or other radionuclides that produce a similar radiation dose pattern may be released. Forty-two dogs with 91 Y initial body burdens from 64 to 1300 μCi/kg body weight was placed in four groups with mean lung burdens of 310, 180, 75 and 40 μCi/kg body weight. These dogs and 12 control dogs are being maintained for lifetime observation. An additional group of four dogs with a mean initial 91 Y body burden of 180 μCi/kg body weight was placed in a sacrifice study. Twenty-six of the exposed dogs and four of the control dogs have died. Eleven dogs within the highest activity level groups died or were euthanized at 12 to 33 days after inhalation of 91 Y with changes related to severe bone marrow damage and associated pancytopenia. Two dogs died approximately one year after 91 Y inhalation with convulsive seizures that were presumed to be unrelated to the 91 Y exposure. Nine 91 Y-exposed dogs died or were euthanized due to neoplasms 2012 to 4115 days after exposure. Three dogs had nasal squamous cell carcinomas, one had a bronchioloalveolar carcinoma, one a mast cell sarcoma, one a mammary adenocarcinoma, one a malignant lymphoma, one a melanosarcoma in the mouth and one heart base tumor. Two dogs died of renal failure 2663 and 4086 days after exposure. One dog died with autoimmune hemolytic anemia 3888 days after exposure and one died with congestive heart failure 4042 days after inhalation exposure. One control dog died of empyema, another control dog died with a mammary adenocarcinoma, one died with congestive heart failure and one with malabsorption syndrome. Serial observations are continuing on all surviving dogs

  19. Division XII / Commission 41 / Working Group Historical Instruments

    Science.gov (United States)

    Pigatto, Luisa; Il-Seong, Nha; Hamel, Jürgen; Johnson, Kevin; Kochhar, Rajesh K.; Nakamura, Tsuko; Orchiston, Wayne; Pettersen, Bjørn R.; Schechner, Sara J.; Yunli, Shi

    The Historical Instruments Working Group (WG-HI) and Commission 41 started planning an interdisciplinary conference titled Astronomy and its instruments before and after Galileo since January 2007. This conference, as an IYA2009 initiative, aims “to highlight mankind's path toward an improved knowledge of the sky using mathematical and mechanical tools as well as monuments and buildings, giving rise, in doing so, to scientific astronomy”. Commission 46 and Commission 55 also support this conference, to be held on the Isle of San Servolo, Venice (Italy), 27 September 3 October 2009. As a fact of history, it was in Venice that Galileo was advised and got material (glass) to make his telescope, and in Venice he presented an working instrument to Venetian Doge in August 1609. The conference is co-sponsored by IAU as a Joint Symposium with the INAF Astronomical Observatory of Padova, Italy.

  20. Division XII / Commission 14 / Working Group Collision Processes

    Science.gov (United States)

    Peach, Gillian; Dimitrijevic, Milan S.; Stancil, Phillip C.

    Research in atomic and molecular collision processes and spectral line broadening has been very active since our last report (Schultz & Stancil 2007, Allard & Peach 2007). Given the large volume of the published literature and the limited space available, we have attempted to identify work most relevant to astrophysics. Since our report is not comprehensive, additional publications can be found in the databases at the web addresses listed in the final section. Elastic and inelastic collisions among electrons, atoms, ions, and molecules are included and reactive processes are also considered, but except for charge exchange, they receive only sparse coverage.

  1. The Path of Carbon in Photosynthesis XII. Some Temperature Effects

    Science.gov (United States)

    Ouellet, C.

    1951-06-25

    The photosynthetic assimilation of radioactive carbon dioxide for two-minute periods by Scenedesmus has bee studied at temperatures ranging from 25? to 44? C. All labeled intermediates cease to be formed at about 45? C. With rising temperature, the radioactivity reaching the sugar phosphate reservoirs decreases regularly while there is a sharp maximum in sucrose at 37? C. and a less pronounced one in malic and aspartic acids about 40? C. A tentative interpretation of these effects is offered.

  2. 30. IX kuni 31. XII 2000 toimus Makedoonia Vabariigis...

    Index Scriptorium Estoniae

    2001-01-01

    III rahvusvaheline graafikatriennaal "Bitola 2000" teemadel "2000 aastat kristlust" ja "Metamorfoos". Eestist osalesid Peeter Allik, Sirje Eelma, Kelli Kagovere, Avo Keerend, Ilmar Kruusamäe, Raul Meel, Benjamin Vasserman. Peapreemia - poola graafiku Mira Boczniowiczi töö "Empire Sign".

  3. Division XII: Commission 55: Communicating Astronomy with the Public

    Science.gov (United States)

    Christensen, Lars Lindberg; Russo, Pedro; Robson, Ian; Arcand, Kimberly Kowal; Fienberg, Richard Tresch; Ödman-Govender, Carolina; Sekiguchi, Kazuhiro; Wheeler, Pete; Zhu, Jin

    2015-08-01

    A good fraction of the Commission 55 (C55) Organizing Committee met in Beijing in August at the XXVIII IAU General Assembly, where C55 organized Special Session 14 (SpS14) entitled ``Communicating Astronomy with the Public for Scientists.'' During our C55 business meeting, and again during an impromptu gathering a few days later, we discussed changes in the IAU's organizational and programmatic structure and how these changes might affect C55. This report summarizes key points and offers some ideas about what we're calling ``C55 v2.0.'' For background and reference, see the C55 website at http://www.communicatingastronomy.org.

  4. Human factors

    International Nuclear Information System (INIS)

    Brown, G.J.

    1991-01-01

    Recent reactor accidents have spurred the major review, described here, of the contribution of operator personnel to safety in Scottish Nuclear Power Stations. The review aims to identify factors leading to the Chernobyl accident and take preventative measures to avoid possible recurrence. Scottish Nuclear power stations aim to remove the operator from a position where failure to take correct action could lead to a safety hazard. Instead operators concentrate on routine and breakdown maintenance and measures are taken to minimize the probability of operator error. The review concluded that most safety procedures were satisfactory but safety analysis supported by good design practices may offer a significant reduction in the risk of operator error. (UK)

  5. [Денис Хрусталëв. Северные крестоносцы: Русь в борьбе за сферы влияния в Восточной Прибалтике XII-XIII вв.] / Andris Šnē

    Index Scriptorium Estoniae

    Šnē, Andris, 1973-

    2012-01-01

    Arvustus: Хрусталëв, Денис. Северные крестоносцы: Русь в борьбе за сферы влияния в Восточной Прибалтике XII-XIII вв. (Санкт-Петербург: Евразия, 2009)

  6. DNA barcoding for identification of 'Candidatus Phytoplasmas' using a fragment of the elongation factor Tu gene.

    Directory of Open Access Journals (Sweden)

    Olga Makarova

    Full Text Available Phytoplasmas are bacterial phytopathogens responsible for significant losses in agricultural production worldwide. Several molecular markers are available for identification of groups or strains of phytoplasmas. However, they often cannot be used for identification of phytoplasmas from different groups simultaneously or are too long for routine diagnostics. DNA barcoding recently emerged as a convenient tool for species identification. Here, the development of a universal DNA barcode based on the elongation factor Tu (tuf gene for phytoplasma identification is reported.We designed a new set of primers and amplified a 420-444 bp fragment of tuf from all 91 phytoplasmas strains tested (16S rRNA groups -I through -VII, -IX through -XII, -XV, and -XX. Comparison of NJ trees constructed from the tuf barcode and a 1.2 kbp fragment of the 16S ribosomal gene revealed that the tuf tree is highly congruent with the 16S rRNA tree and had higher inter- and intra- group sequence divergence. Mean K2P inter-/intra- group divergences of the tuf barcode did not overlap and had approximately one order of magnitude difference for most groups, suggesting the presence of a DNA barcoding gap. The use of the tuf barcode allowed separation of main ribosomal groups and most of their subgroups. Phytoplasma tuf barcodes were deposited in the NCBI GenBank and Q-bank databases.This study demonstrates that DNA barcoding principles can be applied for identification of phytoplasmas. Our findings suggest that the tuf barcode performs as well or better than a 1.2 kbp fragment of the 16S rRNA gene and thus provides an easy procedure for phytoplasma identification. The obtained sequences were used to create a publicly available reference database that can be used by plant health services and researchers for online phytoplasma identification.

  7. Heart disease - risk factors

    Science.gov (United States)

    Heart disease - prevention; CVD - risk factors; Cardiovascular disease - risk factors; Coronary artery disease - risk factors; CAD - risk ... a certain health condition. Some risk factors for heart disease you cannot change, but some you can. ...

  8. Important prognostic factors in patients with skull base erosion from nasopharyngeal carcinoma after radiotherapy

    International Nuclear Information System (INIS)

    Lu, T.-X.; Mai, W.-Y.; Teh, Bin S.; Hu, Y.-H.; Lu, Hsin H.; Chiu, J. Kam; Carpenter, L. Steven; Woo, Shiao Y.; Butler, E. Brian

    2001-01-01

    Purpose: To evaluate the long-term outcome and prognostic factors in patients with skull base erosion from nasopharyngeal carcinoma after initial radiotherapy (RT). Methods and Materials: From January 1985 to December 1986, 100 patients (71 males, 29 females) with a diagnosis of nasopharyngeal carcinoma were found on computed tomography (CT) to have skull base erosion. The mean age was 41 years (range 16-66). Ninety-six patients had World Health Organization type III undifferentiated carcinoma, and 4 had type I. The metastatic workup, including chest radiography, liver ultrasound scanning, and liver function test was negative. All patients underwent external beam RT (EBRT) alone to 66-80 Gy during 6-8 weeks. A daily fraction size of 2 Gy was delivered using 60 Co or a linear accelerator. No patient received chemotherapy. All patients were followed at regular intervals after irradiation. The median follow-up was 22.3 months (range 2-174). Survival of the cohort was computed by the Kaplan-Meier method. The potential prognostic factors of survival were examined. Multivariate analyses were performed using the Cox regression model. Results: The 1, 2, 5, and 10-year overall survival rate for the cohort was 79%, 41%, 27%, and 13%, respectively. However, the subgroup of patients with both anterior cranial nerve (I-VIII) and posterior cranial nerve (IX-XII) involvement had a 5-year survival of only 7.7%. A difference in the time course of local recurrence and distant metastasis was observed. Both local recurrence and distant metastasis often occurred within the first 2 years after RT. However, local relapse continued to occur after 5 years. In contrast, no additional distant metastases were found after 5 years. The causes of death included local recurrence (n=59), distant metastasis (n=21), both local recurrence and distant metastasis (n = 1), and unrelated causes (n=5). After multivariate analysis, complete recovery of cranial nerve involvement, cranial nerve palsy, and

  9. Electroweak form factors

    International Nuclear Information System (INIS)

    Singh, S.K.

    2002-01-01

    The present status of electroweak nucleon form factors and the N - Δ transition form factors is reviewed. Particularly the determination of dipole mass M A in the axial vector form factor is discussed

  10. Risk Factors for Scleroderma

    Science.gov (United States)

    ... You are here: Home For Patients Risk Factors Risk Factors for Scleroderma The cause of scleroderma is ... what biological factors contribute to scleroderma pathogenesis. Genetic Risk Scleroderma does not tend to run in families ...

  11. Risk Factors and Prevention

    Science.gov (United States)

    ... Resources Risk Factors & Prevention Back to Patient Resources Risk Factors & Prevention Even people who look healthy and ... Blood Pressure , high cholesterol, diabetes, and thyroid disease. Risk Factors For Arrhythmias and Heart Disease The following ...

  12. Factors and factorizations of graphs proof techniques in factor theory

    CERN Document Server

    Akiyama, Jin

    2011-01-01

    This book chronicles the development of graph factors and factorizations. It pursues a comprehensive approach, addressing most of the important results from hundreds of findings over the last century. One of the main themes is the observation that many theorems can be proved using only a few standard proof techniques. This stands in marked contrast to the seemingly countless, complex proof techniques offered by the extant body of papers and books. In addition to covering the history and development of this area, the book offers conjectures and discusses open problems. It also includes numerous explanatory figures that enable readers to progressively and intuitively understand the most important notions and proofs in the area of factors and factorization.

  13. Amplification factor variable amplifier

    NARCIS (Netherlands)

    Akitsugu, Oshita; Nauta, Bram

    2007-01-01

    PROBLEM TO BE SOLVED: To provide an amplification factor variable amplifier capable of achieving temperature compensation of an amplification factor over a wide variable amplification factor range. ; SOLUTION: A Gilbert type amplification factor variable amplifier 11 amplifies an input signal and

  14. Amplification factor variable amplifier

    NARCIS (Netherlands)

    Akitsugu, Oshita; Nauta, Bram

    2010-01-01

    PROBLEM TO BE SOLVED: To provide an amplification factor variable amplifier capable of achieving temperature compensation of an amplification factor over a wide variable amplification factor range. ;SOLUTION: A Gilbert type amplification factor variable amplifier 11 amplifies an input signal and can

  15. Foundations of factor analysis

    CERN Document Server

    Mulaik, Stanley A

    2009-01-01

    Introduction Factor Analysis and Structural Theories Brief History of Factor Analysis as a Linear Model Example of Factor AnalysisMathematical Foundations for Factor Analysis Introduction Scalar AlgebraVectorsMatrix AlgebraDeterminants Treatment of Variables as Vectors Maxima and Minima of FunctionsComposite Variables and Linear Transformations Introduction Composite Variables Unweighted Composite VariablesDifferentially Weighted Composites Matrix EquationsMulti

  16. Blood coagulation factor VIII

    Indian Academy of Sciences (India)

    Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the ...

  17. Constructivism, Factoring, and Beliefs.

    Science.gov (United States)

    Rauff, James V.

    1994-01-01

    Discusses errors made by remedial intermediate algebra students in factoring polynomials in light of student definitions of factoring. Found certain beliefs about factoring to logically imply many of the errors made. Suggests that belief-based teaching can be successful in teaching factoring. (16 references) (Author/MKR)

  18. Factors affecting construction performance: exploratory factor analysis

    Science.gov (United States)

    Soewin, E.; Chinda, T.

    2018-04-01

    The present work attempts to develop a multidimensional performance evaluation framework for a construction company by considering all relevant measures of performance. Based on the previous studies, this study hypothesizes nine key factors, with a total of 57 associated items. The hypothesized factors, with their associated items, are then used to develop questionnaire survey to gather data. The exploratory factor analysis (EFA) was applied to the collected data which gave rise 10 factors with 57 items affecting construction performance. The findings further reveal that the items constituting ten key performance factors (KPIs) namely; 1) Time, 2) Cost, 3) Quality, 4) Safety & Health, 5) Internal Stakeholder, 6) External Stakeholder, 7) Client Satisfaction, 8) Financial Performance, 9) Environment, and 10) Information, Technology & Innovation. The analysis helps to develop multi-dimensional performance evaluation framework for an effective measurement of the construction performance. The 10 key performance factors can be broadly categorized into economic aspect, social aspect, environmental aspect, and technology aspects. It is important to understand a multi-dimension performance evaluation framework by including all key factors affecting the construction performance of a company, so that the management level can effectively plan to implement an effective performance development plan to match with the mission and vision of the company.

  19. The joy of factoring

    CERN Document Server

    Wagstaff, Samuel S

    2013-01-01

    This book is about the theory and practice of integer factorization presented in a historic perspective. It describes about twenty algorithms for factoring and a dozen other number theory algorithms that support the factoring algorithms. Most algorithms are described both in words and in pseudocode to satisfy both number theorists and computer scientists. Each of the ten chapters begins with a concise summary of its contents. The book starts with a general explanation of why factoring integers is important. The next two chapters present number theory results that are relevant to factoring. Further on there is a chapter discussing, in particular, mechanical and electronic devices for factoring, as well as factoring using quantum physics and DNA molecules. Another chapter applies factoring to breaking certain cryptographic algorithms. Yet another chapter is devoted to practical vs. theoretical aspects of factoring. The book contains more than 100 examples illustrating various algorithms and theorems. It also co...

  20. Factor VII deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000548.htm Factor VII deficiency To use the sharing features on this page, please enable JavaScript. Factor VII (seven) deficiency is a disorder caused by a ...

  1. Annual Adjustment Factors

    Data.gov (United States)

    Department of Housing and Urban Development — The Department of Housing and Urban Development establishes the rent adjustment factors - called Annual Adjustment Factors (AAFs) - on the basis of Consumer Price...

  2. Stroke - risk factors

    Science.gov (United States)

    ... oxygen. Brain cells can die, causing lasting damage. Risk factors are things that increase your chance of ... a disease or condition. This article discusses the risk factors for stroke and things you can do ...

  3. Human factors in training

    International Nuclear Information System (INIS)

    Dutton, J.W.; Brown, W.R.

    1981-01-01

    The Human Factors concept is a focused effort directed at those activities which require human involvement. Training is, by its nature, an activity totally dependent on the Human Factor. This paper identifies several concerns significant to training situations and discusses how Human Factor awareness can increase the quality of learning. Psychology in the training arena is applied Human Factors. Training is a method of communication represented by sender, medium, and receiver. Two-thirds of this communications model involves the human element directly

  4. Neutron electromagnetic form factors

    International Nuclear Information System (INIS)

    Finn, J.M.; Madey, R.; Eden, T.; Markowitz, P.; Rutt, P.M.; Beard, K.; Anderson, B.D.; Baldwin, A.R.; Keane, D.; Manley, D.M.; Watson, J.W.; Zhang, W.M.; Kowalski, S.; Bertozzi, W.; Dodson, G.; Farkhondeh, M.; Dow, K.; Korsch, W.; Tieger, D.; Turchinetz, W.; Weinstein, L.; Gross, F.; Mougey, J.; Ulmer, P.; Whitney, R.; Reichelt, T.; Chang, C.C.; Kelly, J.J.; Payerle, T.; Cameron, J.; Ni, B.; Spraker, M.; Barkhuff, D.; Lourie, R.; Verst, S.V.; Hyde-Wright, C.; Jiang, W.-D.; Flanders, B.; Pella, P.; Arenhoevel, H.

    1992-01-01

    Nucleon form factors provide fundamental input for nuclear structure and quark models. Current knowledge of neutron form factors, particularly the electric form factor of the neutron, is insufficient to meet these needs. Developments of high-duty-factor accelerators and polarization-transfer techniques permit new experiments that promise results with small sensitivities to nuclear models. We review the current status of the field, our own work at the MIT/Bates linear accelerator, and future experimental efforts

  5. Disconnected electromagnetic form factors

    International Nuclear Information System (INIS)

    Wilcox, Walter

    2001-01-01

    Preliminary results of a calculation of disconnected nucleon electromagnetic factors factors on the lattice are presented. The implementation of the numerical subtraction scheme is outlined. A comparison of results for electric and magnetic disconnected form factors on two lattice sizes with those of the Kentucky group is presented. Unlike previous results, the results found in this calculation are consistent with zero in these sectors

  6. Mesonic Form Factors

    Energy Technology Data Exchange (ETDEWEB)

    Frederic D. R. Bonnet; Robert G. Edwards; George T. Fleming; Randal Lewis; David Richards

    2003-07-22

    We have started a program to compute the electromagnetic form factors of mesons. We discuss the techniques used to compute the pion form factor and present preliminary results computed with domain wall valence fermions on MILC asqtad lattices, as well as Wilson fermions on quenched lattices. These methods can easily be extended to rho-to-gamma-pi transition form factors.

  7. demographic factors associated factors associated with malaria

    African Journals Online (AJOL)

    userpc

    .8%) than those in other nce of 35.4% which was actors can predispose alence of malaria in a study were significantly eveloping guidelines and more effective disease endemic areas (Bashar et therefore attempts to rmation on possible demographic factors d out in four selected geria; Major Ibrahim B. Hospital Zaria, Hajiya.

  8. Aspects of QCD factorization

    International Nuclear Information System (INIS)

    Neubert, Matthias

    2001-01-01

    The QCD factorization approach provides the theoretical basis for a systematic analysis of nonleptonic decay amplitudes of B mesons in the heavy-quark limit. After recalling the basic ideas underlying this formalism, several tests of QCD factorization in the decays B→D (*) L, B→K * γ, and B→πK, ππ are discussed. It is then illustrated how factorization can be used to obtain new constraints on the parameters of the unitarity triangle

  9. Oversimplifying quantum factoring.

    Science.gov (United States)

    Smolin, John A; Smith, Graeme; Vargo, Alexander

    2013-07-11

    Shor's quantum factoring algorithm exponentially outperforms known classical methods. Previous experimental implementations have used simplifications dependent on knowing the factors in advance. However, as we show here, all composite numbers admit simplification of the algorithm to a circuit equivalent to flipping coins. The difficulty of a particular experiment therefore depends on the level of simplification chosen, not the size of the number factored. Valid implementations should not make use of the answer sought.

  10. What Are Rare Clotting Factor Deficiencies?

    Science.gov (United States)

    ... Deficiency Factor V Deficiency Combined FV & FVIII Deficiencies Factor VII Deficiency Factor X Deficiency Factor XI Deficiency Factor ... Deficiency Factor V Deficiency Combined FV & FVIII Deficiencies Factor VII Deficiency Factor X Deficiency Factor XI Deficiency Factor ...

  11. Risk factors and prevention of injuries to the cranial nerves in reconstructive surgery of the carotid arteries.

    Science.gov (United States)

    Voskanian, Iu E; Kolomeĭtsev, S N; Shniukov, R V

    2005-01-01

    Reconstructive operations on aortic arch branches is the most effective approach to prevention of acute and chronic disorders of cerebral circulation. Iatrogenic injuries to the cranial nerves worsen the early end, particularly, the late postoperative period, decrease the quality of life and the social status of patients who had undergone carotid reconstructions. The aim of the study was to improve the short- and long-term results of reconstructive operations on the carotid arteries by means of minimizing the incidence and severity of iatrogenic injuries to the cranial nerves. The study accrued 149 patients undergoing operations on the carotid arteries for atherosclerosis or pathologic tortuosity. Of these 82 patients forming the control group were examined for the incidence and character of injuries to the cranial nerves. Neuropathy of the cranial nerves (CN) was identified in 16 (19.5%) patients (7 patients had injuries to the hypoglossal nerve, 3 to the facial nerve, 5 to the vagus; one patient presented with coexistent injury to the glossopharyngeal and pharyngeal branches of the vagus). The clinically and statistically significant risk factors of injuries were: minor surgical experience, the high loop of the internal carotid artery (ICA), lengthy atherosclerotic stenosis greater than 2 cm, diabetes mellitus, intraoperative trauma of the area of the cranial nerves, high mobilization of the ICA, the lack of visualization of pairs X and XII of the CN, intraoperative bleeding, intersection of the superior radix of the deep cervical loop, edema and hematoma of the neck in the postoperative period, and early unscheduled reoperations. One month later the cumulative stability of cranial dysfunction accounted for 62.5%, after 3 months it accounted for 43.8%, after 6 months for 31.2 , after 9 months for 18.8%, and after 12 months for 6,2%. In patients with injury to the CN, analysis of the quality of life made in the late postoperative period revealed its lowering with

  12. PAYMENT CAPACITY SENSITIVITY FACTORS

    Directory of Open Access Journals (Sweden)

    Daniel BRÎNDESCU – OLARIU

    2014-11-01

    The results of the study facilitate the determination and classification of the main sensitivity factors for the payment capacity at sample level, the establishment of general benchmarks for the payment capacity (as no such benchmarks currently exist in the Romanian literature and the identification of the mechanisms through which the variation of different factors impacts the payment capacity.

  13. Respirator field performance factors

    International Nuclear Information System (INIS)

    Skaggs, B.J.; DeField, J.D.; Strandberg, S.W.; Sutcliffe, C.R.

    1985-01-01

    The Industrial Hygiene Group assisted OSHA and the NRC in measurements of respirator performance under field conditions. They reviewed problems associated with sampling aerosols within the respirator in order to determine fit factors (FFs) or field performance factor (FPF). In addition, they designed an environmental chamber study to determine the effects of temperature and humidity on a respirator wearer

  14. Factors affecting nuclear development

    International Nuclear Information System (INIS)

    Stevens, G.H.; Girouard, P.

    1995-01-01

    Among the factors affecting nuclear development, some depend more or less on public authorities, but many are out of public authorities control (foreign policies, market and deregulation, socials and environmental impacts, public opinion). As far as possible, the following study tries to identify those factors. (D.L.). 2 photos

  15. Soil Forming Factors

    Science.gov (United States)

    It! What is Soil? Chip Off the Old Block Soil Forming Factors Matters of Life and Death Underneath It All Wise Choices A World of Soils Soil Forming Factors 2 A Top to Bottom Guide 3 Making a Soil Monolith 4 Soil Orders 5 State Soil Monoliths 6 Where in the Soil World Are You? >> A Top to

  16. Perspectivas Pedagogicas. Documentos-Ponencias Y Ensayos Proyecto Teacher Corps, Ciclo XII (Pedagogical Perspectives. Documents, Papers and Essays, Teacher Corps Project, Cycle XII).

    Science.gov (United States)

    Albino, Isidra, Ed.; Davila, Sonia, Ed.

    The purpose of this book is to stimulate ideas leading to a sharing of approaches, strategies, and methodologies applicable to the education of Puerto Ricans. Following introductory material, 18 papers are presented, the first 10 of which are in Spanish. Titles and authors are: (1) "El maestro que Puerto Rico necesita," Leonides Santos…

  17. Two-factor authentication

    CERN Document Server

    Stanislav, Mark

    2015-01-01

    During the book, readers will learn about the various technical methods by which two-factor authentication is implemented, security concerns with each type of implementation, and contextual details to frame why and when these technologies should be used. Readers will also be provided with insight about the reasons that two-factor authentication is a critical security control, events in history that have been important to prove why organization and individual would want to use two factor, and core milestones in the progress of growing the market.

  18. Business Intelligence Success Factors

    DEFF Research Database (Denmark)

    Gaardboe, Rikke; Jonasen, Tanja Svarre

    2018-01-01

    Business intelligence (BI) is a strategically important practice in many organizations. Several studies have investigated the factors that contribute to BI success; however, an overview of the critical success factors (CSFs) involved is lacking in the extant literature. We have integrated...... 34 CSFs related to BI success. The distinct CSFs identified in the extant literature relate to project management skills (13 papers), management support (20 papers), and user involvement (11 papers). In the articles with operationalized BI success, we found several distinct factors: system quality...

  19. Human factor reliability program

    International Nuclear Information System (INIS)

    Knoblochova, L.

    2017-01-01

    The human factor's reliability program was at Slovenske elektrarne, a.s. (SE) nuclear power plants. introduced as one of the components Initiatives of Excellent Performance in 2011. The initiative's goal was to increase the reliability of both people and facilities, in response to 3 major areas of improvement - Need for improvement of the results, Troubleshooting support, Supporting the achievement of the company's goals. The human agent's reliability program is in practice included: - Tools to prevent human error; - Managerial observation and coaching; - Human factor analysis; -Quick information about the event with a human agent; -Human reliability timeline and performance indicators; - Basic, periodic and extraordinary training in human factor reliability(authors)

  20. [Human factors in medicine].

    Science.gov (United States)

    Lazarovici, M; Trentzsch, H; Prückner, S

    2017-01-01

    The concept of human factors is commonly used in the context of patient safety and medical errors, all too often ambiguously. In actual fact, the term comprises a wide range of meanings from human-machine interfaces through human performance and limitations up to the point of working process design; however, human factors prevail as a substantial cause of error in complex systems. This article presents the full range of the term human factors from the (emergency) medical perspective. Based on the so-called Swiss cheese model by Reason, we explain the different types of error, what promotes their emergence and on which level of the model error prevention can be initiated.

  1. Shell Buckling Knockdown Factors

    Data.gov (United States)

    National Aeronautics and Space Administration — The Shell Buckling Knockdown Factor (SBKF) Project, NASA Engineering and Safety Center (NESC) Assessment #: 07-010-E, was established in March of 2007 by the NESC in...

  2. Risk factors for neoplasms

    International Nuclear Information System (INIS)

    Brachner, A.; Grosche, B.

    1991-06-01

    A broad survey is given of risk factors for neoplasms. The main carcinogenic substances (including also ionizing radiation and air pollution) are listed, and are correlated with the risk factors for various cancers most frequently explained and discussed in the literature. The study is intended to serve as a basis for a general assessment of the incidence of neoplasms in children, and of cancer mortality in the entire population of Bavaria in the years 1983-1989, or 1979-1988, respectively, with the principal idea of drawing up an environment-related health survey. The study therefore takes into account not only ionizing radiation as a main risk factor, but also other risk factors detectable within the ecologic context, as e.g. industrial installations and their effects, refuse incineration plants or waste dumps, or the social status. (orig./MG) [de

  3. Factor IX assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003679.htm Factor IX assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  4. Factor VIII assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003678.htm Factor VIII assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  5. Factor II assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003674.htm Factor II assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  6. Factor V deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000550.htm Factor V deficiency To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  7. Rheumatoid factor (RF)

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003548.htm Rheumatoid factor (RF) To use the sharing features on this ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  8. Factor II deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000549.htm Factor II deficiency To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  9. Factor VII assay

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003676.htm Factor VII assay To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  10. Factor X deficiency

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000553.htm Factor X deficiency To use the sharing features on ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  11. New microbial growth factor

    Science.gov (United States)

    Bok, S. H.; Casida, L. E., Jr.

    1977-01-01

    A screening procedure was used to isolate from soil a Penicillium sp., two bacterial isolates, and a Streptomyces sp. that produced a previously unknown microbial growth factor. This factor was an absolute growth requirement for three soil bacteria. The Penicillium sp. and one of the bacteria requiring the factor, an Arthrobacter sp., were selected for more extensive study concerning the production and characteristics of the growth factor. It did not seem to be related to the siderochromes. It was not present in soil extract, rumen fluid, or any other medium component tested. It appears to be a glycoprotein of high molecular weight and has high specific activity. When added to the diets for a meadow-vole mammalian test system, it caused an increased consumption of diet without a concurrent increase in rate of weight gain.

  12. Human factors in aviation

    National Research Council Canada - National Science Library

    Salas, Eduardo; Maurino, Daniel E

    2010-01-01

    .... HFA offers a comprehensive overview of the topic, taking readers from the general to the specific, first covering broad issues, then the more specific topics of pilot performance, human factors...

  13. [Risk factors of schizophrenia].

    Science.gov (United States)

    Suvisaari, Jaana

    2010-01-01

    Schizophrenia is a multifactorial, neurodevelopmental disorder caused by a combination of genetic and environmental risk factors. Disturbances of brain development begin prenatally, while different environmental insults further affect postnatal brain maturation during childhood and adolescence. Genome-wide association studies (GWAS) have succeeded in identifying hundreds of new risk variants for common, multifactorial diseases. In schizophrenia research, GWAS have found several rare copy number variants that considerably increase the risk of schizophrenia, and have shown an association between schizophrenia and the major histocompatibility complex. Research on environmental risk factors in recent years has provided new information particularly on risk factors related to pregnancy and childhood rearing environment. Gene-environment interactions have become a central research topic. There is evidence that genetically susceptible children are more vulnerable to the effects of unstable childhood rearing environment and other environmental risk factors.

  14. Human Factors Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose: The purpose of the Human Factors Laboratory is to further the understanding of highway user needs so that those needs can be incorporated in roadway design,...

  15. Factors Affecting Wound Healing

    Science.gov (United States)

    Guo, S.; DiPietro, L.A.

    2010-01-01

    Wound healing, as a normal biological process in the human body, is achieved through four precisely and highly programmed phases: hemostasis, inflammation, proliferation, and remodeling. For a wound to heal successfully, all four phases must occur in the proper sequence and time frame. Many factors can interfere with one or more phases of this process, thus causing improper or impaired wound healing. This article reviews the recent literature on the most significant factors that affect cutaneous wound healing and the potential cellular and/or molecular mechanisms involved. The factors discussed include oxygenation, infection, age and sex hormones, stress, diabetes, obesity, medications, alcoholism, smoking, and nutrition. A better understanding of the influence of these factors on repair may lead to therapeutics that improve wound healing and resolve impaired wounds. PMID:20139336

  16. The stem factor challenge

    International Nuclear Information System (INIS)

    Russell, M.J.; Steele, R. Jr.; DeWall, K.G.; Watkins, J.C.; Bramwell, D.

    1994-01-01

    One of the most important challenges that still needs to be met in the effort to understand the operation of motor-operated, rising-stem valves is the ability to determine stem factor throughout the valve's load range. The stem factor represents the conversion of operator torque to stem thrust. Determining the stem factor is important because some motor-operated valves (MOVs) cannot be tested in the plant at design basis conditions. The ability of these valves to perform their design basis function (typically, to operate against specified flow and pressure loads) must be ensured by analytical methods or by extrapolating from the results of tests conducted at lower loads. Because the stem factor tends to vary in response to friction and lubrication phenomena that occur during loading and wedging, analytical methods and extrapolation methods have been difficult to develop and implement. Early investigations into variability in the stem factor tended to look only at the tip of the iceberg; they focused on what was happening at torque switch trip, which usually occurs at full wedging. In most stems, the stem factor is better (lower) in the wedging transient than before wedging, so working with torque switch trip data alone led many early researchers to false conclusions about the relationship between stem factor and load. However, research at the Idaho National Engineering Laboratory (INEL) has taken a closer look at what happens during the running portion of the closing stroke along with the wedging portion. This shift in focus is important, because functional failure of a valve typically consists of a failure to isolate flow, not a failure to achieve full wedging. Thus, the stem factor that must be determined for a valve's design basis closing requirements is the one that corresponds with the running load before wedging

  17. Factors Affecting Wound Healing

    OpenAIRE

    Guo, S.; DiPietro, L.A.

    2010-01-01

    Wound healing, as a normal biological process in the human body, is achieved through four precisely and highly programmed phases: hemostasis, inflammation, proliferation, and remodeling. For a wound to heal successfully, all four phases must occur in the proper sequence and time frame. Many factors can interfere with one or more phases of this process, thus causing improper or impaired wound healing. This article reviews the recent literature on the most significant factors that affect cutane...

  18. Los factores de riesgo

    Directory of Open Access Journals (Sweden)

    Justo Senado Dumoy

    1999-01-01

    Full Text Available Sobre el fundamento filosófico de los conceptos de la Dialéctica Materialista, se presenta un análisis en relación con el concepto e interpretación de los Factores de Riesgo.A analysis on the concept and interpretation of risk factors is presented based on the philosophical foundation of the concepts of materialist dialectics.

  19. Brain derived neurotrophic factor

    DEFF Research Database (Denmark)

    Mitchelmore, Cathy; Gede, Lene

    2014-01-01

    Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin with important functions in neuronal development and neuroplasticity. Accumulating evidence suggests that alterations in BDNF expression levels underlie a variety of psychiatric and neurological disorders. Indeed, BDNF therapies are curre......Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin with important functions in neuronal development and neuroplasticity. Accumulating evidence suggests that alterations in BDNF expression levels underlie a variety of psychiatric and neurological disorders. Indeed, BDNF therapies...

  20. Factors Impacting Knowledge Sharing

    DEFF Research Database (Denmark)

    Schulzmann, David; Slepniov, Dmitrij

    The purpose of this paper is to examine various factors affecting knowledge sharing at the R&D center of a Western MNE in China. The paper employs qualitative methodology and is based on the action research and case study research techniques. The findings of the paper advance our understanding...... about factors that affect knowledge sharing. The main emphasis is given to the discussion on how to improve knowledge sharing in global R&D organizations....

  1. FGF growth factor analogs

    Science.gov (United States)

    Zamora, Paul O [Gaithersburg, MD; Pena, Louis A [Poquott, NY; Lin, Xinhua [Plainview, NY; Takahashi, Kazuyuki [Germantown, MD

    2012-07-24

    The present invention provides a fibroblast growth factor heparin-binding analog of the formula: ##STR00001## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X, Y and Z are as defined, pharmaceutical compositions, coating compositions and medical devices including the fibroblast growth factor heparin-binding analog of the foregoing formula, and methods and uses thereof.

  2. Factorization and pion form factor in QCD

    International Nuclear Information System (INIS)

    Efremov, A.V.; Radyushkin, A.V.

    1979-01-01

    The behaviour of the pion electromagnetic form factor (EMFF) in the framework of quantum chromodynamics (QCD) is discussed. Pion is considered to be a quark-antiquark bound state. It is proposed to use an OPE description of the bound state structure by matrix elements of certain local gauge-invariant operators. Short-distance quark interactions is proved using a direct analysis of perturbation theory in the α-parametric representation of the Feynman diagrams. It is shown that the short-distance parton picture privides a self-consistent description of the large Q 2 momentum behaviour of the pion EMFF in QCD. Pion EMFF asymptotics is expressed in terms of fu fundamental constants of the theory

  3. Polyphosphate nanoparticles on the platelet surface trigger contact system activation

    NARCIS (Netherlands)

    Verhoef, Johan J F; Barendrecht, Arjan D; Nickel, Katrin F; Dijkxhoorn, Kim; Kenne, Ellinor; Labberton, Linda; McCarty, Owen J T; Schiffelers, Raymond; Heijnen, Harry F G; Hendrickx, Antoni P A; Schellekens, Huub; Fens, Marcel H; de Maat, Steven; Renné, Thomas; Maas, Coen

    2017-01-01

    Polyphosphate is an inorganic polymer that can potentiate several interactions in the blood coagulation system. Blood platelets contain polyphosphate, and the secretion of platelet-derived polyphosphate has been associated with increased thrombus formation and activation of coagulation factor XII.

  4. [Pathological gambling: risk factors].

    Science.gov (United States)

    Bouju, G; Grall-Bronnec, M; Landreat-Guillou, M; Venisse, J-L

    2011-09-01

    In France, consumption of gambling games increased by 148% between 1960 and 2005. In 2004, gamblers lost approximately 0.9% of household income, compared to 0.4% in 1960. This represents approximately 134 Euros per year and per head. In spite of this important increase, the level remains lower than the European average (1%). However, gambling practices may continue to escalate in France in the next few years, particularly with the recent announce of the legalisation of online games and sports betting. With the spread of legalised gambling, pathological gambling rates may increase in France in the next years, in response to more widely available and more attractive gambling opportunities. In this context, there is a need for better understanding of the risk factors that are implicated in the development and maintenance of pathological gambling. This paper briefly describes the major risk factors for pathological gambling by examining the recent published literature available during the first quarter of 2008. This documentary basis was collected by Inserm for the collective expert report procedure on Gambling (contexts and addictions). Seventy-two articles focusing on risk factors for pathological gambling were considered in this review. Only 47 of them were taken into account for analysis. The selection of these 47 publications was based on the guide on literature analysis established by the French National Agency for Accreditation and Assessment in Health (ANAES, 2000). Some publications from more recent literature have also been added, mostly about Internet gambling. We identify three major types of risk factors implicated in gambling problems: some of them are related to the subject (individual factors), others are related to the object of the addiction, here the gambling activity by itself (structural factors), and the last are related to environment (contextual or situational factors). Thus, the development and maintenance of pathological gambling seems to be

  5. Generalised Batho correction factor

    International Nuclear Information System (INIS)

    Siddon, R.L.

    1984-01-01

    There are various approximate algorithms available to calculate the radiation dose in the presence of a heterogeneous medium. The Webb and Fox product over layers formulation of the generalised Batho correction factor requires determination of the number of layers and the layer densities for each ray path. It has been shown that the Webb and Fox expression is inefficient for the heterogeneous medium which is expressed as regions of inhomogeneity rather than layers. The inefficiency of the layer formulation is identified as the repeated problem of determining for each ray path which inhomogeneity region corresponds to a particular layer. It has been shown that the formulation of the Batho correction factor as a product over inhomogeneity regions avoids that topological problem entirely. The formulation in terms of a product over regions simplifies the computer code and reduces the time required to calculate the Batho correction factor for the general heterogeneous medium. (U.K.)

  6. factores psicosociales asociados

    Directory of Open Access Journals (Sweden)

    María Teresa Varela Arévalo

    2007-01-01

    Full Text Available El objetivo de este trabajo fue describir el consumo de sustancias psicoactivas [SPA] ilegales en jóvenes y los factores psicosociales de riesgo y de protección asociados. Participaron 763 estudiantes (46,5% hombres y 52,4% mujeres de una universidad privada de Cali, quienes diligenciaron el cuestionario de factores de riesgo y protección para el consumo de drogas. Los resultados muestran que la marihuana fue la droga de mayor consumo; y que existe una fuerte asociación entre el consumo de las cuatro SPA ilegales (marihuana, opiáceos, cocaína y éxtasis y los factores psicosociales de riesgo y/o protección, principalmente, las habilidades de autocontrol, los preconceptos y valoración de las SPA, la relación con personas consumidoras y los comportamientos perturbadores.

  7. Multi-factor authentication

    Science.gov (United States)

    Hamlet, Jason R; Pierson, Lyndon G

    2014-10-21

    Detection and deterrence of spoofing of user authentication may be achieved by including a cryptographic fingerprint unit within a hardware device for authenticating a user of the hardware device. The cryptographic fingerprint unit includes an internal physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generates a PUF value. Combining logic is coupled to receive the PUF value, combines the PUF value with one or more other authentication factors to generate a multi-factor authentication value. A key generator is coupled to generate a private key and a public key based on the multi-factor authentication value while a decryptor is coupled to receive an authentication challenge posed to the hardware device and encrypted with the public key and coupled to output a response to the authentication challenge decrypted with the private key.

  8. Human factors guides

    International Nuclear Information System (INIS)

    Penington, J.

    1995-10-01

    This document presents human factors guides, which have been developed in order to provide licensees of the AECB with advice as to how to address human factors issues within the design and assessment process. This documents presents the results of a three part study undertaken to develop three guides which are enclosed in this document as Parts B, C and D. As part of the study human factors standards, guidelines, handbooks and other texts were researched, to define those which would be most useful to the users of the guides and for the production of the guides themselves. Detailed specifications were then produced to outline the proposed contents and format of the three guides. (author). 100 refs., 3 tabs., 11 figs

  9. Human factors guides

    Energy Technology Data Exchange (ETDEWEB)

    Penington, J [PHF Services Inc., (Canada)

    1995-10-01

    This document presents human factors guides, which have been developed in order to provide licensees of the AECB with advice as to how to address human factors issues within the design and assessment process. This documents presents the results of a three part study undertaken to develop three guides which are enclosed in this document as Parts B, C and D. As part of the study human factors standards, guidelines, handbooks and other texts were researched, to define those which would be most useful to the users of the guides and for the production of the guides themselves. Detailed specifications were then produced to outline the proposed contents and format of the three guides. (author). 100 refs., 3 tabs., 11 figs.

  10. The focus factor

    DEFF Research Database (Denmark)

    Nicolaisen, Jeppe; Frandsen, Tove Faber

    2015-01-01

    Introduction. We present a new bibliometric indicator to measure journal specialisation over time, named the focus factor. This new indicator is based on bibliographic coupling and counts the percentage of re-citations given in subsequent years. Method. The applicability of the new indicator....... To validate re-citations as caused by specialisation, other possible causes were measured and correlated (obsolescence, journal self-citations and number of references). Results. The results indicate that the focus factor is capable of distinguishing between general and specialised journals and thus...... effectively measures the intended phenomenon (i.e., journal specialisation). Only weak correlations were found between journal re-citations and obsolescence, journal self-citations, and number of references. Conclusions. The focus factor successfully measures journal specialisation over time. Measures based...

  11. WRKY transcription factors

    Science.gov (United States)

    Bakshi, Madhunita; Oelmüller, Ralf

    2014-01-01

    WRKY transcription factors are one of the largest families of transcriptional regulators found exclusively in plants. They have diverse biological functions in plant disease resistance, abiotic stress responses, nutrient deprivation, senescence, seed and trichome development, embryogenesis, as well as additional developmental and hormone-controlled processes. WRKYs can act as transcriptional activators or repressors, in various homo- and heterodimer combinations. Here we review recent progress on the function of WRKY transcription factors in Arabidopsis and other plant species such as rice, potato, and parsley, with a special focus on abiotic, developmental, and hormone-regulated processes. PMID:24492469

  12. On braid monodromy factorizations

    International Nuclear Information System (INIS)

    Kharlamov, V M; Kulikov, Vik S

    2003-01-01

    We introduce and develop a language of semigroups over the braid groups to study the braid monodromy factorizations (bmf's) of plane algebraic curves and other related objects. As an application, we give a new proof of Orevkov's theorem on the realization of bmf's over a disc by algebraic curves and show that the complexity of such a realization cannot be bounded in terms of the types of factors of the bmf. We also prove that the type of a bmf distinguishes Hurwitz curves with singularities of inseparable type up to H-isotopy and J-holomorphic cuspidal curves in CP 2 up to symplectic isotopy

  13. Dose conversion factors

    International Nuclear Information System (INIS)

    Kocher, D.C.; Eckerman, K.F.

    1992-01-01

    The following is discussed in this report: concepts and quantities used in calculating radiation dose from internal and external exposure. Tabulations of dose conversion factor for internal and external exposure to radionuclides. Dose conversion factors give dose per unit intake (internal) or dose per unit concentration in environment (external). Intakes of radionuclides for internal exposure and concentrations of radionuclides in environment for external exposure are assumed to be known. Intakes and concentrations are obtained, e.g., from analyses of environmental transport and exposure pathways. differences between dosimetry methods for radionuclides and hazardous chemicals are highlighted

  14. Factors stimulating content marketing

    Directory of Open Access Journals (Sweden)

    Naser Azad

    2016-02-01

    Full Text Available This paper presents an empirical investigation to determine factors influencing on content marketing in banking industry. The study designs a questionnaire consists of 40 questions in Likert scale and distributes it among 550 randomly selected regular customers of Bank Mellat in city of Tehran, Iran and 400 properly filled questionnaires are collected. Cronbach alphas for all components of the survey are well above desirable level. Using principle component analysis with Varimax rotation, the study has determined six factors influencing the most on content marketing including organization, details, having new ideas, quality, sensitivity and power while the last component contains only two subcomponents and is removed from the study.

  15. STEREOTYPICAL FACTORS IN TOURISM

    Directory of Open Access Journals (Sweden)

    Cristina-Elena ALBU

    2013-06-01

    Full Text Available International tourism has grown rapidly nowdays, contributing to the growth of the global economy. The purpose of this essay is to identify and analyze stereotypical factors in the development of strategies concerning the offer for the tourism industry: the image of a tourist destination, brand, country of origin and customer behaviour. Documentary study was the research method used: representative articles were analysed, as recent as possible, to determine the factors mentioned above. Professionals in the industry of tourism need to understand cultural differences between tourists, as well as those of the host country, to be able to create tourist reception offers that live up to the standards expected by clients.

  16. Factor analysis and scintigraphy

    International Nuclear Information System (INIS)

    Di Paola, R.; Penel, C.; Bazin, J.P.; Berche, C.

    1976-01-01

    The goal of factor analysis is usually to achieve reduction of a large set of data, extracting essential features without previous hypothesis. Due to the development of computerized systems, the use of largest sampling, the possibility of sequential data acquisition and the increase of dynamic studies, the problem of data compression can be encountered now in routine. Thus, results obtained for compression of scintigraphic images were first presented. Then possibilities given by factor analysis for scan processing were discussed. At last, use of this analysis for multidimensional studies and specially dynamic studies were considered for compression and processing [fr

  17. The Transcription Factor Encyclopedia

    DEFF Research Database (Denmark)

    Yusuf, Dimas; Butland, Stefanie L; Swanson, Magdalena I

    2012-01-01

    mini review articles on pertinent human, mouse and rat TFs. Notable features of the TFe website include a high-quality PDF generator and web API for programmatic data retrieval. TFe aims to rapidly educate scientists about the TFs they encounter through the delivery of succinct summaries written......ABSTRACT: Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130...

  18. Factorizations and physical representations

    International Nuclear Information System (INIS)

    Revzen, M; Khanna, F C; Mann, A; Zak, J

    2006-01-01

    A Hilbert space in M dimensions is shown explicitly to accommodate representations that reflect the decomposition of M into prime numbers. Representations that exhibit the factorization of M into two relatively prime numbers: the kq representation (Zak J 1970 Phys. Today 23 51), and related representations termed q 1 q 2 representations (together with their conjugates) are analysed, as well as a representation that exhibits the complete factorization of M. In this latter representation each quantum number varies in a subspace that is associated with one of the prime numbers that make up M

  19. Model Correction Factor Method

    DEFF Research Database (Denmark)

    Christensen, Claus; Randrup-Thomsen, Søren; Morsing Johannesen, Johannes

    1997-01-01

    The model correction factor method is proposed as an alternative to traditional polynomial based response surface techniques in structural reliability considering a computationally time consuming limit state procedure as a 'black box'. The class of polynomial functions is replaced by a limit...... of the model correction factor method, is that in simpler form not using gradient information on the original limit state function or only using this information once, a drastic reduction of the number of limit state evaluation is obtained together with good approximations on the reliability. Methods...

  20. [Natural factors influencing sleep].

    Science.gov (United States)

    Jurkowski, Marek K; Bobek-Billewicz, Barbara

    2007-01-01

    Sleep is a universal phenomenon of human and animal lives, although the importance of sleep for homeo-stasis is still unknown. Sleep disturbances influence many behavioral and physiologic processes, leading to health complications including death. On the other hand, sleep improvement can beneficially influence the course of healing of many disorders and can be a prognostic of health recovery. The factors influencing sleep have different biological and chemical origins. They are classical hormones, hypothalamic releasing and inhibitory hormones, neuropeptides, peptides and others as cytokines, prostaglandins, oleamid, adenosine, nitric oxide. These factors regulate most physiologic processes and are likely elements integrating sleep with physiology and physiology with sleep in health and disorders.

  1. Environmental factors and leukaemia

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, L

    1985-01-01

    Investigations on the association between environmental hazards and the development of various types of leukaemia are reviewed. Regarding acute non-lymphocytic leukaemia (ANLL) exposure to ionizing radiation is a well-documented risk factor. According to several recent studies exposure to strong electromagnetic fields may be suspected to be of etiologic importance for ANLL. There is evidence that occupational handling of benzene is a risk factor and other organic solvents may also be leukaemogenic. Occupational exposure to petrol products has been proposed to be a risk factor although the hazardous substances have not yet been defined. Results of cytogenetic studies in ANLL suggest that exposure to certain environmental agents may be associated with relatively specific clonal chromosome aberrations. Exposure in utero to ionizing radiation has been proposed to be a risk factor for acute lymphocytic leukaemia (ALL) in children. Unlike ANLL there seems at present to be little evidence that ALL is related to exposure to some chemicals. Chronic myeloid leukaemia (CML) may follow exposure to high doses of ionizing radiation whereas such exposure seems to be of insignificant importance for the development of chronic lymphocytic leukaemia (CLL). According to some studies an abnormally high incidence of CLL may be found among farmers in the USA. These results have not been confirmed in Scandinavian studies. There seems to be little evidence that CML or CLL are related to occupational handling of some chemicals. 35 references.

  2. Hyperglycemia: a prothrombotic factor?

    NARCIS (Netherlands)

    Lemkes, B. A.; Hermanides, J.; DeVries, J. H.; Holleman, F.; Meijers, J. C. M.; Hoekstra, J. B. L.

    2010-01-01

    Diabetes mellitus is characterized by a high risk of atherothrombotic events. What is more, venous thrombosis has also been found to occur more frequently in this patient group. This prothrombotic condition in diabetes is underpinned by laboratory findings of elevated coagulation factors and

  3. Thermal disadvantage factor

    International Nuclear Information System (INIS)

    Abdullah, K.M.S.; Loyalka, S.K.

    1990-01-01

    A method is described where reactor cell flux and the disadvantage factor are calculated by using diffusion theory in the moderator and integral transport in the fuel. The method is efficient (noniterative) and provides results that agree well with Monte Carlo, P 5 and ABH results

  4. Threshold factorization redux

    Science.gov (United States)

    Chay, Junegone; Kim, Chul

    2018-05-01

    We reanalyze the factorization theorems for the Drell-Yan process and for deep inelastic scattering near threshold, as constructed in the framework of the soft-collinear effective theory (SCET), from a new, consistent perspective. In order to formulate the factorization near threshold in SCET, we should include an additional degree of freedom with small energy, collinear to the beam direction. The corresponding collinear-soft mode is included to describe the parton distribution function (PDF) near threshold. The soft function is modified by subtracting the contribution of the collinear-soft modes in order to avoid double counting on the overlap region. As a result, the proper soft function becomes infrared finite, and all the factorized parts are free of rapidity divergence. Furthermore, the separation of the relevant scales in each factorized part becomes manifest. We apply the same idea to the dihadron production in e+e- annihilation near threshold, and show that the resultant soft function is also free of infrared and rapidity divergences.

  5. Fibroblast growth factor 23

    African Journals Online (AJOL)

    Dr Olaleye

    Systemic phosphate homeostasis is maintained through several hormonal mechanisms which involve fibroblast growth factor 23 (FGF-23), α-klotho, vitamin D and parathyroid hormone. FGF-23 is known to be the major regulator of phosphate balance (Mirams et al., 2004). FGF-23 is a phosphaturic hormone, which is.

  6. Human factors information system

    International Nuclear Information System (INIS)

    Goodman, P.C.; DiPalo, C.A.

    1991-01-01

    Nuclear power plant safety is dependent upon human performance related to plant operations. To provide improvements in human performance, data collection and assessment play key roles. This paper reports on the Human factors Information System (HFIS) which is designed to meet the needs of the human factors specialists of the United States Nuclear Regulatory Commission. These specialists identify personnel errors and provide guidance designed to prevent such errors. HFIS is a simple and modular system designed for use on a personal computer. It is designed to contain four separate modules that provide information indicative of program or function effectiveness as well as safety-related human performance based on programmatic and performance data. These modules include the Human Factors Status module; the Regulatory Programs module; the Licensee Event Report module; and the Operator Requalification Performance module. Information form these modules can either be used separately or can be combined due to the integrated nature of the system. HFIS has the capability, therefore, to provide insights into those areas of human factors that can reduce the probability of events caused by personnel error at nuclear power plants and promote the health and safety of the public. This information system concept can be applied to other industries as well as the nuclear industry

  7. PATTERNS AND FACTORS INVOLVED

    African Journals Online (AJOL)

    Between 1*' of July 1996 and 30'h of June 2000 a total of 3583 patients were registered at the accident and emergency unit of Nnamdi. Azikiwe ... The case files of these were reviewed with a view to ascertaining the causes and factors involved in the deaths of these patients. The .... H.I.V/AIDS related complications 23 6.8.

  8. Introduction to human factors

    International Nuclear Information System (INIS)

    Winters, J.M.

    1988-03-01

    Some background is given on the field of human factors. The nature of problems with current human/computer interfaces is discussed, some costs are identified, ideal attributes of graceful system interfaces are outlined, and some reasons are indicated why it's not easy to fix the problems

  9. Prognostic factors in oligodendrogliomas

    DEFF Research Database (Denmark)

    Westergaard, L; Gjerris, F; Klinken, L

    1997-01-01

    An outcome analysis was performed on 96 patients with pure cerebral oligodendrogliomas operated in the 30-year period 1962 to 1991. The most important predictive prognostic factors were youth and no neurological deficit, demonstrated as a median survival for the group younger than 20 years of 17...

  10. Factors affecting mining costs

    International Nuclear Information System (INIS)

    Lowell, A.F.

    1977-01-01

    The subject is discussed under the following headings: investment decision-making, unit cost factors (declining ore grade, low-price contracts, ore grade/output relationship, above average cost increases). Economic, environmental, sociological and political aspects are considered. (U.K.)

  11. Human factors in network security

    OpenAIRE

    Jones, Francis B.

    1991-01-01

    Human factors, such as ethics and education, are important factors in network information security. This thesis determines which human factors have significant influence on network security. Those factors are examined in relation to current security devices and procedures. Methods are introduced to evaluate security effectiveness by incorporating the appropriate human factors into network security controls

  12. Electromagnetic form factors

    International Nuclear Information System (INIS)

    Desplanques, B.

    1987-01-01

    Electromagnetic form factors, in first approximation, are sensitive to spatial distribution of nucleons and to their current. In second approximation, more precise effects are concerned, whose role is increasing with momentum transfer and participating essentially of short range nuclei description. They concern of course the nucleon-nucleon interaction while approaching each other and keeping their free-state identity, but also mutually polarizing one the other. In this last effect, radial and orbital excitations of nucleon, the nucleon mesonic cloud modification and the nucleon antinucleon pair excitation are included. In this paper, these contributions are discussed while trying to find the important elements for a good description of form factors. Current questions are also discussed. Light nuclei are essentially concerned [fr

  13. Researching organizational factors

    International Nuclear Information System (INIS)

    Coffman, F.

    1991-01-01

    This paper discusses feedback and insights from experience (both successful and unsuccessful) with the past and the ongoing organizational factors research. That experience suggests a leading set of ingredients that appear proper for performing regulatory research on organizational processes. By keeping focused upon these proper ingredients, the research will contribute to the regulatory assessments of utility management through the use of improved methods and measures in investigations, inspections, diagnostics, performance indicators, and PRA insights. This paper is organized into (1) an introductory description of what the agency is doing to assess organizational effectiveness, (2) some insights from past and ongoing research, (3) an opinion on a leading set of ingredients to properly research organizational factors, and (4) a summary

  14. On braid monodromy factorizations

    Energy Technology Data Exchange (ETDEWEB)

    Kharlamov, V M [Institut de Recherche Matematique Avanee Universite Louis Pasteur et CNRS 7 rue Rene Descartes (France); Kulikov, Vik S [Steklov Mathematical Institute, Russian Academy of Sciences (Russian Federation)

    2003-06-30

    We introduce and develop a language of semigroups over the braid groups to study the braid monodromy factorizations (bmf's) of plane algebraic curves and other related objects. As an application, we give a new proof of Orevkov's theorem on the realization of bmf's over a disc by algebraic curves and show that the complexity of such a realization cannot be bounded in terms of the types of factors of the bmf. We also prove that the type of a bmf distinguishes Hurwitz curves with singularities of inseparable type up to H-isotopy and J-holomorphic cuspidal curves in CP{sup 2} up to symplectic isotopy.

  15. Factors in Agile Methods Adoption

    Directory of Open Access Journals (Sweden)

    Samia Abdalhamid

    2017-05-01

    Full Text Available There are many factors that can affect the process of adopting Agile methods during software developing. This paper illustrates the critical factors in Agile methods adoption in software organizations. To present the success and failure factors, an exploratory study is carried out among the critical factors of success and failure from existing studies. Dimensions and Factors are introduced utilizing success and failure dimensions. The mind map was used to clarify these factors.

  16. Factors of academic procrastination

    OpenAIRE

    Kranjec, Eva; Košir, Katja; Komidar, Luka

    2017-01-01

    This study investigated dimensions of perfectionism, anxiety, and depression as factors of academic procrastination. Our main research interest was to examine the role of specific dimensions of perfectionism as moderators in the relationship between anxiety and depression and academic procrastination. Four scales were administered on the sample of 403 students: perfectionism scale FMPS, academic procrastination scale APS-SI, depression scale CESD and anxiety scale STAI-X2. The results showed ...

  17. Concentration factors for fish

    International Nuclear Information System (INIS)

    Feldt, W.; Lauer, R.; Melzer, M.; Siebert, W.

    1978-01-01

    Concentration factors are defined as operators allowing to calculate the specific activity of fish meat from a given concentration of an element in the water. This parameter depends among others from the content of stable isotopes and homologues in the different waters. If this parameter is reasonably to be used for model calculations it must be referred to water with all of its content substances, these calculations also being based on this type of 'water'. (orig.) [de

  18. Prognostic factors for medulloblastoma

    International Nuclear Information System (INIS)

    Jenkin, Derek; Al Shabanah, Mohamed; Al Shail, Essam; Gray, Alan; Hassounah, Maher; Khafaga, Yasser; Kofide, Amani; Mustafa, Mahmoud; Schultz, Henrik

    2000-01-01

    Purpose: To evaluate prognostic factors for medulloblastoma. Methods and Materials: One hundred and seventy-three consecutive patients with medulloblastoma, treated at King Faisal Specialist Hospital (KFSH) from 1988-1997, were reviewed. Eighty-four percent were children less than 15 years old. From 1988-1994, treatment was at the discretion of the investigator. From 1994-1998, patients entered a single-arm best practice protocol in which, in staged patients, the surgical intent was total resection, standard radiation treatment was defined, and adjuvant chemotherapy was given to a 'high-risk' subset. Results: For 150 patients who completed surgical and radiation treatment, the 5-year survival rate was 58%, compared with 0% for 16 patients who were unable to start or complete radiation treatment. For staged patients, the 5-year survival was M0 + M1, 78% and M2 + M3, 21% (p 14 years and gross cystic/necrotic features in the primary tumor. The size of the primary tumor, the degree of hydrocephalus at diagnosis, the presence of residual tumor in the post-operative CT/MRI, and the functional status of the patient prior to radiation treatment were not significant factors. Conclusions: Stage M0 + M1 was the most powerful favorable prognostic factor. In Saudi Arabia more patients present with advanced disseminated disease, 41% M2 + M3, than in the West, and this impacts adversely on overall survival. Total resection and standard radiation treatment were not sensitive prognostic factors in a treatment environment in which 78% of patients underwent at least 90% tumor resection and 60% received standard radiation treatment. In order to improve the proportion of patients able to complete radiation treatment, consideration should be given to limiting resection when the attainment of total resection is likely to be morbid, and to delaying rather than omitting radiation treatment in the patient severely compromised postoperatively

  19. Risk factors for cancer

    International Nuclear Information System (INIS)

    Lyman, G.H.

    1992-01-01

    It is no longer reasonable to divide cancers into those that are genetic in origin and those that are environmental in origin. With rare exception, carcinogenesis involves environmental factors that directly or indirectly exert a change in the cell's genome. Virtually all causes of cancer are multifactorial, sometimes involving an inherited predisposition to the carcinogenic effects of environmental factors, which include chemicals, ionizing radiation, and oncogenic virus. Carcinogenesis is a multistep process including induction, promotion, and progression. Initiation requires an irreversible change in the cellular genome, whereas promotion is commonly associated with prolonged and reversible exposure. Tumor progression results in genotypic and phenotypic changes associated with tumor growth, invasion, and metastasis. Most information on human cancer risk is based on epidemiologic studies involving both exposed and unexposed individuals. The quality of such studies depends on their ability to assess the strength of any association of exposure and disease and careful attention to any potential bias. Few cancers are inherited in a Mendelian fashion. Several preneoplastic conditions, however, are clearly inherited and several malignancies demonstrate weak familial patterns. Environmental factors may exert their effect on DNA in a random fashion, but certain consistent changes, including specific translocations of genetic information, are often found. Currently, there is great interest in the close proximity of certain oncogenes governing growth control to the consistent chromosomal changes observed. Such changes may represent a final common pathway of action for environmental carcinogens. Sufficient laboratory and epidemiologic evidence exists to establish a causal association of several chemical agents with cancer

  20. Human factoring administrative procedures

    International Nuclear Information System (INIS)

    Grider, D.A.; Sturdivant, M.H.

    1991-01-01

    In nonnuclear business, administrative procedures bring to mind such mundane topics as filing correspondence and scheduling vacation time. In the nuclear industry, on the other hand, administrative procedures play a vital role in assuring the safe operation of a facility. For some time now, industry focus has been on improving technical procedures. Significant efforts are under way to produce technical procedure requires that a validated technical, regulatory, and administrative basis be developed and that the technical process be established for each procedure. Producing usable technical procedures requires that procedure presentation be engineered to the same human factors principles used in control room design. The vital safety role of administrative procedures requires that they be just as sound, just a rigorously formulated, and documented as technical procedures. Procedure programs at the Tennessee Valley Authority and at Boston Edison's Pilgrim Station demonstrate that human factors engineering techniques can be applied effectively to technical procedures. With a few modifications, those same techniques can be used to produce more effective administrative procedures. Efforts are under way at the US Department of Energy Nuclear Weapons Complex and at some utilities (Boston Edison, for instance) to apply human factors engineering to administrative procedures: The techniques being adapted include the following

  1. Human Factors Review Plan

    International Nuclear Information System (INIS)

    Paramore, B.; Peterson, L.R.

    1985-12-01

    ''Human Factors'' is concerned with the incorporation of human user considerations into a system in order to maximize human reliability and reduce errors. This Review Plan is intended to assist in the assessment of human factors conditions in existing DOE facilities. In addition to specifying assessment methodologies, the plan describes techniques for improving conditions which are found to not adequately support reliable human performance. The following topics are addressed: (1) selection of areas for review describes techniques for needs assessment to assist in selecting and prioritizing areas for review; (2) human factors engineering review is concerned with optimizing the interfaces between people and equipment and people and their work environment; (3) procedures review evaluates completeness and accuracy of procedures, as well as their usability and management; (4) organizational interface review is concerned with communication and coordination between all levels of an organization; and (5) training review evaluates training program criteria such as those involving: trainee selection, qualification of training staff, content and conduct of training, requalification training, and program management

  2. Human Factors Review Plan

    Energy Technology Data Exchange (ETDEWEB)

    Paramore, B.; Peterson, L.R. (eds.)

    1985-12-01

    ''Human Factors'' is concerned with the incorporation of human user considerations into a system in order to maximize human reliability and reduce errors. This Review Plan is intended to assist in the assessment of human factors conditions in existing DOE facilities. In addition to specifying assessment methodologies, the plan describes techniques for improving conditions which are found to not adequately support reliable human performance. The following topics are addressed: (1) selection of areas for review describes techniques for needs assessment to assist in selecting and prioritizing areas for review; (2) human factors engineering review is concerned with optimizing the interfaces between people and equipment and people and their work environment; (3) procedures review evaluates completeness and accuracy of procedures, as well as their usability and management; (4) organizational interface review is concerned with communication and coordination between all levels of an organization; and (5) training review evaluates training program criteria such as those involving: trainee selection, qualification of training staff, content and conduct of training, requalification training, and program management.

  3. Human and Organizational Factors

    International Nuclear Information System (INIS)

    Eshiett, P.B.S.

    2016-01-01

    The Human and Organizational Factors Approach to Industrial Safety (HOFS) consists of identifying and putting in place conditions which encourage a positive contribution from operators (individually and in a team) with regards to industrial safety. The knowledge offered by the HOFS approach makes it possible better to understand what conditions human activity and to act on the design of occupational situations and the organization, in the aim of creating the conditions for safe work. Efforts made in this area can also lead to an improvement in results in terms of the quality of production or occupational safety (incidence and seriousness rates) (Daniellou, F., et al., 2011). Research on industrial accidents shows that they rarely happen as a result of a single event, but rather emerge from the accumulation of several, often seemingly trivial, malfunctions, misunderstandings, incorrect assumptions and other issues. The nuclear community has established rigorous international safety standards and concepts to ensure the protection of people and the environment from harmful effects of ionizing radiation (IAEA, 2014). A review of major human induced disasters in a number of countries and in different industries yields insights into several of the human and organizational factors involved in their occurrence. Some of these factors relate to failures in: • Design or technology; • Training; • Decision making; • Communication; • Preparation for the unexpected; • Understanding of organizational interdependencies

  4. Molecular factors in migraine

    Science.gov (United States)

    Kowalska, Marta; Prendecki, Michał; Kozubski, Wojciech; Lianeri, Margarita; Dorszewska, Jolanta

    2016-01-01

    Migraine is a common neurological disorder that affects 11% of adults worldwide. This disease most likely has a neurovascular origin. Migraine with aura (MA) and more common form - migraine without aura (MO) – are the two main clinical subtypes of disease. The exact pathomechanism of migraine is still unknown, but it is thought that both genetic and environmental factors are involved in this pathological process. The first genetic studies of migraine were focused on the rare subtype of MA: familial hemiplegic migraine (FHM). The genes analysed in familial and sporadic migraine are: MTHFR, KCNK18, HCRTR1, SLC6A4, STX1A, GRIA1 and GRIA3. It is possible that migraine is a multifactorial disease with polygenic influence. Recent studies have shown that the pathomechanisms of migraine involves both factors responsible for immune response and oxidative stress such as: cytokines, tyrosine metabolism, homocysteine; and factors associated with pain transmission and emotions e.g.: serotonin, hypocretin-1, calcitonin gene-related peptide, glutamate. The correlations between genetic variants of the HCRTR1 gene, the polymorphism 5-HTTLPR and hypocretin-1, and serotonin were observed. It is known that serotonin inhibits the activity of hypocretin neurons and may affect the appearance of the aura during migraine attack. The understanding of the molecular mechanisms of migraine, including genotype-phenotype correlations, may contribute to finding markers important for the diagnosis and treatment of this disease. PMID:27191890

  5. Structuring factoring business: accounting aspects

    Directory of Open Access Journals (Sweden)

    I.M. Vygivska

    2017-08-01

    Full Text Available The article theoretically substantiates the fact that factoring belongs to the main operational activity of a factoring company, and this allowed structuring the factoring business by types of activity. The lack of a unified approach to the classification of factoring (factoring services made it possible to systematize and refine their classification as a basis for developing accounting and analytical support for risk management of factoring business. The authors single out such classification signs as: the right of the reverse claim (reverse, irretrievable, a territorial feature (international, internal, the subject of the factoring contract (real, consensual, the availability of notification of the debtor (conventional, confidential. The structuring of factoring business contributes to the identification of the risks of the economic activities of a factoring company depending on the type of factoring, the development of methodological support for the bookkeeping of factoring transactions in a risk environment, the search for risk management practices and the determination of management effectiveness in general.

  6. Milestones and Impact Factors

    Directory of Open Access Journals (Sweden)

    Grandjean Philippe

    2010-07-01

    Full Text Available Abstract Environmental Health has just received its first Impact Factor by Thomson ISI. At a level of 2.48, this achievement is quite satisfactory and places Environmental Health in the top 25% of environmental science journals. When the journal was launched in 2002, it was still unclear whether the Open Access publishing model could be made into a viable commercial enterprise within the biomedical field. During the past eight years, Open Access journals have become widely available, although still covering only about 15% of journal titles. Major funding agencies and institutions, including prominent US universities, now require that researchers publish in Open Access journals. Because of the profound role of scientific journals for the sharing of results and communication between researchers, the advent of Open Access may be of as much significance as the transition from handwriting to printing via moveable type. As Environmental Health is an electronic Open Access journal, the numbers of downloads at the journal website can be retrieved. The top-20 list of articles most frequently accessed shows that all of them have been downloaded over 10,000 times. Back in 2002, the first article published was accessed only 49 times during the following month. A year later, the server had over 1,000 downloads per month, and now the total number of monthly downloads approaches 50,000. These statistics complement the Impact Factor and confirm the viability of Open Access in our field of research. The advent of digital media and its decentralized mode of distribution - the internet - have dramatically changed the control and financing of scientific information dissemination, while facilitating peer review, accelerating editorial handling, and supporting much needed transparency. Both the meaning and means of "having an impact" are therefore changing, as will the degree and way in which scientific journals remain "factors" in that impact.

  7. Factor 4 planning

    International Nuclear Information System (INIS)

    Bariol-Mathais, Brigitte; Lavoillotte, Philippine; Gall-Sorrentino, Florence; Malez, Marianne; Sanna, Daniela; Marsauche, Maud; Marquet, Sarah; Debergue, Sophie; Aminu, Olufunmi; Bernard, Helene; Marchand, Jean-Michel; Blin, Frederic; Grange, Jerome; Caillierez, Sophie; Muller, Dania; Clement, Bob; Desire, Jean-Charles; Metais, Benedicte; Lannuzel, Philippe; Pezet-Kuhn, Murielle; Pons, Anne; Rivoire-Meley, Benedicte; Tissot, Heloise

    2015-07-01

    Factor 4 is the goal of cutting our greenhouse gas emissions by 75% by 2050. Achieving this objective will necessitate radical changes in our practices, in particular concerning transport and housing; the measures currently implemented, such as positive-energy buildings, low-impact mobility and eco-neighbourhoods, will not be enough to meet this goal. These measures must be conceived in the framework of broad territorial planning that integrates environmental and energy objectives far upstream. To this end, the French Environment and Energy Management Agency (ADEME) and the French network of Urban Planning Agencies (FNAU), pursuing their missions in their respective areas of competence, have joined forces to make infrastructure and land use planning an integral part of the environmental and energy transition process. In 2013, the two organisations signed a partnership agreement and compiled an inventory of practices that are relevant to Factor 4 planning. This work was led by Epures, Saint-etienne urban planning agency, along with FNAU, drawing upon the expertise of a dozen urban planning agencies in precursor territories. This inventory describes the stakes, resources and strengths for each territory, which have led to cross-sectoral territorial planning exercises with ambitious environmental and energy objectives; the importance of evaluation in attaining these goals is emphasised. Current experience, questions and available methodological tools are summarised in this document, to encourage territories and help them design their planning policies along a trajectory to achieve Factor 4 goals. The compilation also aims to be a contribution to the COP21 climate conference

  8. Accidents and human factors

    International Nuclear Information System (INIS)

    Nishiwaki, Y.; Kawai, H.; Morishima, H.; Terano, T.; Sugeno, M.

    1984-01-01

    When the TMI accident occurred it was 4 a.m., an hour when the error potential of the operators would have been very high. The frequency of car and train accidents in Japan is also highest between 4 a.m. and 6 a.m. The error potential may be classified into five phases corresponding to the electroencephalogramic pattern (EEG). At phase 0, when the delta wave appears, a person is unconscious and in deep sleep; at phase I, when the theta wave appears, he is very tired, sleepy and subnormal; at phase II, when the alpha wave appears, he is normal, relaxed and passive; at phase III, when the beta wave appears, he is normal, clear-minded and active; at phase IV, when the strong beta or epileptic wave appears, he is hypernormal, excited and incapable of normal judgement. Should an accident occur at phase II, the brain condition may jump to phase IV. At this phase the error or accident potential is maximum. The response of the human brain to different types of noises and signals may vary somewhat for different individuals and for different groups of people. Therefore, the possibility that such differences in brain functions may influence the mental structure would be worthy of consideration in human factors and in the design of man-machine systems. Human reliability and performance would be affected by many factors: medical, physiological and psychological, etc. The uncertainty involved in human factors may not necessarily be probabilistic, but fuzzy. Therefore, it would be important to develop a theory by which both non-probabilistic uncertainties, or fuzziness, of human factors and the probabilistic properties of machines can be treated consistently. From the mathematical point of view, probabilistic measure is considered a special case of fuzzy measure. Therefore, fuzzy set theory seems to be an effective tool for analysing man-machine systems. To minimize human error and the possibility of accidents, new safety systems should not only back up man and make up for his

  9. Speeding Fermat's factoring method

    Science.gov (United States)

    McKee, James

    A factoring method is presented which, heuristically, splits composite n in O(n^{1/4+epsilon}) steps. There are two ideas: an integer approximation to sqrt(q/p) provides an O(n^{1/2+epsilon}) algorithm in which n is represented as the difference of two rational squares; observing that if a prime m divides a square, then m^2 divides that square, a heuristic speed-up to O(n^{1/4+epsilon}) steps is achieved. The method is well-suited for use with small computers: the storage required is negligible, and one never needs to work with numbers larger than n itself.

  10. Improved Balanced Incomplete Factorization

    Czech Academy of Sciences Publication Activity Database

    Bru, R.; Marín, J.; Mas, J.; Tůma, Miroslav

    2010-01-01

    Roč. 31, č. 5 (2010), s. 2431-2452 ISSN 0895-4798 R&D Projects: GA AV ČR IAA100300802 Grant - others:GA AV ČR(CZ) M100300902 Institutional research plan: CEZ:AV0Z10300504 Source of funding: I - inštitucionálna podpora na rozvoj VO Keywords : preconditioned iterative methods * sparse matrices * incomplete decompositions * approximate inverses * Sherman-Morrison formula * nonsymmetric matrices Subject RIV: BA - General Mathematics Impact factor: 1.725, year: 2010

  11. Sleep-inducing factors.

    Science.gov (United States)

    García-García, Fabio; Acosta-Peña, Eva; Venebra-Muñoz, Arturo; Murillo-Rodríguez, Eric

    2009-08-01

    Kuniomi Ishimori and Henri Piéron were the first researchers to introduce the concept and experimental evidence for a chemical factor that would presumably accumulate in the brain during waking and eventually induce sleep. This substance was named hypnotoxin. Currently, the variety of substances which have been shown to alter sleep includes peptides, cytokines, neurotransmitters and some substances of lipidic nature, many of which are well known for their involvement in other biological activities. In this chapter, we describe the sleep-inducing properties of the vasoactive intestinal peptide, prolactin, adenosine and anandamide.

  12. "Factor Analysis Using ""R"""

    Directory of Open Access Journals (Sweden)

    A. Alexander Beaujean

    2013-02-01

    Full Text Available R (R Development Core Team, 2011 is a very powerful tool to analyze data, that is gaining in popularity due to its costs (its free and flexibility (its open-source. This article gives a general introduction to using R (i.e., loading the program, using functions, importing data. Then, using data from Canivez, Konold, Collins, and Wilson (2009, this article walks the user through how to use the program to conduct factor analysis, from both an exploratory and confirmatory approach.

  13. Perinatal risk factors for strabismus

    DEFF Research Database (Denmark)

    Torp-Pedersen, Tobias; Boyd, Heather A; Poulsen, Gry

    2010-01-01

    Little is known about the aetiological factors underlying strabismus. We undertook a large cohort study to investigate perinatal risk factors for strabismus, overall and by subtype.......Little is known about the aetiological factors underlying strabismus. We undertook a large cohort study to investigate perinatal risk factors for strabismus, overall and by subtype....

  14. Activation of human factor V by factor Xa and thrombin

    International Nuclear Information System (INIS)

    Monkovic, D.D.; Tracy, P.B.

    1990-01-01

    The activation of human factor V by factor Xa and thrombin was studied by functional assessment of cofactor activity and sodium dodecyl sulfate-polycarylamide gel electrophoresis followed by either autoradiography of 125 I-labeled factor V activation products or Western blot analyses of unlabeled factor V activation products. Cofactor activity was measured by the ability of the factor V/Va peptides to support the activation of prothrombin. The factor Xa catalyzed cleavage of factor V was observed to be time, phospholipid, and calcium ion dependent, yielding a cofactor with activity equal to that of thrombin-activated factor V (factor Va). The cleavage pattern differed markedly from the one observed in the bovine system. The factor Xa activated factor V subunits expressing cofactor activity were isolated and found to consist of peptides of M r 220,000 and 105,000. Although thrombin cleaved the M r 220,000 peptide to yield peptides previously shown to be products of thrombin activation, cofactor activity did not increase. N-Terminal sequence analysis confirmed that both factor Xa and thrombin cleave factor V at the same bond to generate the M r 220,000 peptide. The factor Xa dependent functional assessment of 125 I-labeled factor V coupled with densitometric analyses of the cleavage products indicated that the cofactor activity of factor Xa activated factor V closely paralleled the appearance of the M r 220,000 peptide. The data indicate that factor Xa is as efficient an enzyme toward factor V as thrombin

  15. Organizational factors in Korean NPPs

    International Nuclear Information System (INIS)

    Jang, D. J.; Kim, Y. I.; Jeong, C. H.; Kim, J. W.

    2003-01-01

    Organizational factors are referred to as the factors that influence the achievement of a goal of an organization. Latent problems of an organization could contribute to causing human errors in such stages as design, operation and maintenance, and furthermore, leading to an severe accident. In order to evaluate an organization from the safety viewpoint, it is necessary to identify the organizational factors in a systematic fashion. In this paper, some efforts to identify the organizational factors in Korean NPPs are presented. The study was performed in the following steps: 1) Reviewing the definitions and range of the organizational factors used by the previous 13 researches, 2) Structuring the organizational factors by screening and collating factors, 3) Analysing the organizational factors that is considered to have contributed to the trip events based on the trip report of Korean NPPs, 4) Suggesting a more reliable taxonomy of organizational factors for event analysis by applying the Onion Structure Model to the selected factors

  16. Risk Factors in Pemphigus

    Directory of Open Access Journals (Sweden)

    Gülşen Tükenmez Demirc

    2011-09-01

    Full Text Available Background and Design: There have been reports suggesting the involvement of environmental factors in the disease process of pemphigus. In this study, we aimed to find out the risk factors which could play role in the etiopathogenesis in our pemphigus patients.Material and method: A total of 42 patients (15 male and 27 female who were diagnosed as pemphigus with histopathological and direct immunoflurosence examinations in our clinic between the years 1998-2004, were interviewed for assessment of regarding with the subjects of the demographic properties, occupational groups, educational level, the number of pregnancies, stressfull life events, diet habits, smoking and alcohol consumption before the onset of the disease and the results were compared to 42 age and gender-matched controls with similar socioeconomic circumstances. Results: Working in agriculture and livestock, multi-parity, absence of smoking and stressfull life events were found to be statistically significant in pemphigus patients than in controls. Conclusion: Working in agriculture and livestock, multi-parity, absence of smoking and stressfull life events were assumed to play role in the etiopathogenesis and course of pemphigus.

  17. Internal motions in H II regions. XII S162 and NGC 7635

    Energy Technology Data Exchange (ETDEWEB)

    Pismis, P; Moreno, M A; Hasse, I [Universidad Nacional Autonoma de Mexico, Mexico City

    1983-01-01

    The apparent structure of S162 and of the bubble nebula (NGC 7635) associated with it is discussed using a number of direct images taken through narrow band (10 A/sup 0/) interference filters in H..cap alpha.., (N II) and in the continuum at lambda6607. The results are discussed together with the radial velocity field of S162 and in particular of the bubble nebula as obtained from photographic Fabry-Perot interferometry. The bubble nebula is shown to be composed of distinct and amorphous very regularly curving arcs, all inscribed on a tenuous slightly ellipsoidal shell of gas expanding at velocity of about 4 km s/sup -1/. The arcs are probably genetically related to the globules which form the caracteristic comet like feature within the bubble nebula. The ionization source of S162 is BD + 60/sup 0/2522 and 071Isub(b)f star classified from our high dispersion spectrum. Our very tentative suggestion is that the brightest globule may be an offshoot fo this star and that the globule has generated the next globule which in turn may have generated the third one. The configuration of NGC 7635 suggests that magnetic fields are likely to be operative in the region. Polarimetry in the optical and in the radio range as well as high resolution infrared studies, high resolution velocity fields are desirable to find a satisfactory model for this nebula.

  18. Spectra of Nb XII-XVII from a low-inductance vacuum spark

    International Nuclear Information System (INIS)

    Burkhalter, P.G.; Cohen, L.; Cowan, R.D.; Sweeney, B.V.

    1982-01-01

    The XUV spectrum of niobium was obtained by using a low-inductance vaccum spark and grazing-incidence, high-resolution spectrograph. Identification of wavelengths and lines were made in the 2060-A region for complex arrays involving 3d--p and 3d--4f transitions. Atomic structure calculations using relativistically corrected Hartree-Fock wave functions provided the theoretical basis for line classifications. The 3d 9 --3d 8 4p,4f and 3p 5 3d 10 -3p 5 3d 9 4p,4f transitions in Nb XV and satellites to the Ni-like 3d 10 --3d 9 4p,4f lines were classified. Energy levels for the 3d 8 4p and 3d 8 4f configurations in Nb XV were determined by using Slater integrals scaled by least-squares fitting

  19. Un arte de la palabra en la Cataluña del siglo XII

    Directory of Open Access Journals (Sweden)

    Puigarnau, Alfons

    2000-12-01

    Full Text Available In this article the author deals with a cultural approach of some manuscripts and artistic images during the 12th century in Catalonia. Behind this pages there is an intention of not no approaching to the so called Historicism and to check to what extent it is possible to make a History of Medieval Catalan Culture from a more hermeneutic point of view. Primary sources as liturgical manuscripts, wall paintings, altar pannels and inscriptions are used in order to understand the fact that behind all of these 'material culture' there is a "mental habit" of producing cultural and religious ideas in connection with three main aspects: a particular conception of the feudal Promise creating strong relations of power between lord and vassal; a eschatological mentality of being at Iast judged in an Apocalyptical context; and a particular connection of these Promise and Judgement through concepts as Memory and Time. The principal issue that is embodying feudal Promise, last Judgement, Memory and Time is the Art of Word, considering this 'word' as an aesthetic consequence of the historical fact of the Incarnation of Christ as Logos and Wisdom believed as Pantocrator (Omnipotens during the whole European Medieval period.[fr] Cet article propose une approche culturelle à quelques manuscrits et images artistiques du XlIème siècle catalan. Ces pages relèvent d'une intention de dépasser l'historicisme et constituent un essai de vérifier jusqu'à quel point il est possible de réaliser une histoire de la culture médiévale catalane d'un point de vue plus herméneutique. Des sources primaires telles que manuscrits liturgiques, peintures murales, frontais d'autel et inscriptions, sont utilisées pour mieux comprendre le fait que au-delà de cette "cuture matérielle" il existe une "habitude mentale" dans le déploiement d'idées culturelles et religieuses mises en liaison avec trois idées principales: une conception particulière du serment féodal, générateur de forts liens de pouvoir entre le seigneur et son vassal; une mentalité scathologique qui songe au Jugement dernier dans un contexte apocaliptique; et une connection spéciale entre ce Serment et ce Jugement au travers de notions comme la Mémoire et le Temps. L'idée centrale qui relie ces quatre éléments (serment, jugement, mémoire et temps c'est un Art de la Parole. Cette "parole" est ici considérée comme conséquence esthétique du fait de l'Incarnation du Christ comme Logos et Sagesse, adorée dans l'image iconographique du Pantocrator (omnipotens au cours du Moyen Âge européen.

  20. PANCHROMATIC HUBBLE ANDROMEDA TREASURY. XII. MAPPING STELLAR METALLICITY DISTRIBUTIONS IN M31

    Energy Technology Data Exchange (ETDEWEB)

    Gregersen, Dylan; Seth, Anil C. [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112 (United States); Williams, Benjamin F.; Dalcanton, Julianne J.; Johnson, L. C.; Lewis, Alexia R. [Department of Astronomy, Box 351580, University of Washington, Seattle, WA 98195 (United States); Lang, Dustin [McWilliams Center for Cosmology, Department of Physics, Carnegie Mellon University, Pittsburgh, PA 15213 (United States); Girardi, Leó [Osservatorio Astronomico di Padova—INAF, Vicolo dell’Osservatori 5, I-35122 Padova (Italy); Skillman, Evan D. [Minnesota Institute for Astrophysics, University of Minnesota, Minneapolis, MN 55455 (United States); Bell, Eric [Department of Astronomy, University of Michigan, 500 Church Street, Ann Arbor, MI 48109 (United States); Dolphin, Andrew E. [Raytheon, 1151 E. Hermans Road, Tucson, AZ 85706 (United States); Fouesneau, Morgan [MPIA, Koenigstuhl 17, D-69117 Heidelberg (Germany); Guhathakurta, Puragra; Hamren, Katherine M. [UCO/Lick Observatory, University of California at Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 (United States); Kalirai, Jason [Department of Physics and Astronomy, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Monachesi, Antonela [MPA, Garching (Germany); Olsen, Knut, E-mail: dylan.gregersen@utah.edu, E-mail: aseth@astro.utah.edu [NOAO, Tucson, AZ 85719 (United States)

    2015-12-15

    We present a study of spatial variations in the metallicity of old red giant branch stars in the Andromeda galaxy. Photometric metallicity estimates are derived by interpolating isochrones for over seven million stars in the Panchromatic Hubble Andromeda Treasury (PHAT) survey. This is the first systematic study of stellar metallicities over the inner 20 kpc of Andromeda’s galactic disk. We see a clear metallicity gradient of −0.020 ± 0.004 dex kpc{sup −1} from ∼4–20 kpc assuming a constant red giant branch age. This metallicity gradient is derived after correcting for the effects of photometric bias and completeness and dust extinction, and is quite insensitive to these effects. The unknown age gradient in M31's disk creates the dominant systematic uncertainty in our derived metallicity gradient. However, spectroscopic analyses of galaxies similar to M31 show that they typically have small age gradients that make this systematic error comparable to the 1σ error on our metallicity gradient measurement. In addition to the metallicity gradient, we observe an asymmetric local enhancement in metallicity at radii of 3–6 kpc that appears to be associated with Andromeda’s elongated bar. This same region also appears to have an enhanced stellar density and velocity dispersion.

  1. Human Development XII: A Theory for the Structure and Function of the Human Brain

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2008-01-01

    Full Text Available The human brain is probably the most complicated single structure in the biological universe. The cerebral cortex that is traditionally connected with consciousness is extremely complex. The brain contains approximately 1,000,000 km of nerve fibers, indicating its enormous complexity and which makes it difficult for scientists to reveal the function of the brain. In this paper, we propose a new model for brain functions, i.e., information-guided self-organization of neural patterns, where information is provided from the abstract wholeness of the biophysical system of an organism (often called the true self, or the “soul””. We present a number of arguments in favor of this model that provide self-conscious control over the thought process or cognition. Our arguments arise from analyzing experimental data from different research fields: histology, anatomy, electroencephalography (EEG, cerebral blood flow, neuropsychology, evolutionary studies, and mathematics. We criticize the popular network theories as the consequence of a simplistic, mechanical interpretation of reality (philosophical materialism applied to the brain. We demonstrate how viewing brain functions as information-guided self-organization of neural patterns can explain the structure of conscious mentation; we seem to have a dual hierarchical representation in the cerebral cortex: one for sensation-perception and one for will-action. The model explains many of our unique mental abilities to think, memorize, associate, discriminate, and make abstractions. The presented model of the conscious brain also seems to be able to explain the function of the simpler brains, such as those of insects and hydra.

  2. Contactos con la vida material en Zamora : siglos XII-XV

    OpenAIRE

    Bueno Domínguez, María Luisa

    2005-01-01

    El artículo trata de hacer una aproximación a la ciudad de Zamora desde tres puntos de vista. Por una parte, el paulatino ensanchamiento del espacio urbano en función de las pueblas, me he centrado en aquellas que me permitían ofrecer datos más concretos con respecto a la vida de una ciudad medieval en este caso Zamora. Acercándome a los lugares privados, las casas y a los públicos, calles y plazas por donde las personas realizaban su vida cotidiana. En un segundo apartado se hace una valorac...

  3. Extremity War Injuries XII: Homeland Defense as a Translation of War Lessons Learned.

    Science.gov (United States)

    Stinner, Maj Daniel J; Schmidt, Andrew H

    2018-06-12

    The 12th Extremity War Injuries Symposium focused on issues related to the transitions in medical care that are occurring as the focus of the war on terror changes. The symposium highlighted the results of Department of Defense-funded research in musculoskeletal injury, the evolution of combat casualty care, and the readiness of the fighting force. Presentations and discussions focused on force readiness of both troops and their medical support as well as the maintenance of the combat care expertise that has been developed during the previous decade of conflict.

  4. Laser fusion research with GEKKO XII and PW laser system at Osaka

    International Nuclear Information System (INIS)

    Izawa, Y.; Mima, K.; Azechi, H.; Fujioka, S.; Fujita, H.; Fujimoto, Y.; Jitsuno, T.; Johzaki, Y.; Kitagawa, Y.; Kodama, R.; Kondo, K.; Miyanaga, N.; Nagai, K.; Nagatomo, H.; Nakai, M.; Nishihara, K.; Nishimura, H.; Norimatsu, T.; Shiraga, H.; Shigemori, K.; Sunahara, A.; Tanaka, K.A.; Tsubakimoto, K.; Nakao, Y.; Norreys, P.; Sakagami, H.

    2005-01-01

    Fast heating of the compressed core plasma up to 500eV has been successfully demonstrated by injecting a 400J/0.6ps PW laser into a compressed CD shell through a hollow gold cone. According to this result, we started the FIREX (Fast Ignition Realization Experiment) project toward demonstrating the ignition of the highly compressed DT fuel by the high energy PW laser heating. A new heating laser LFEX (Laser for Fast Ignition Experiment) is under construction. In this paper the progresses in the experimental studies on scientific issues related to fast ignition and the integrated code development toward the FIREX will be reported. Research results on implosion hydrodynamics, Rayleigh-Taylor instability growth and a new stabilization mechanism are also reported. (author)

  5. XII International Conference on Beauty, Charm, and Hyperons in Hadronic Interactions (BEACH 2016)

    International Nuclear Information System (INIS)

    2016-01-01

    This volume contains the contributed papers presented at the 12 th International Conference on Hyperons, Charm and Beauty Hadrons , currently known as the BEACH Conferences. The BEACH conferences cover a broad range of physics topics in the field of Hyperon and heavy- flavor physics. This conference continues the BEACH series, which began with a meeting in Strasbourg in 1995 and since then offers a biennial opportunity for both theorists and experimentalists from the high-energy physics community to discuss all aspects of flavour physics. The 12 th Conference took place in the Research Hall Room 163 of the Geoege Mason University in Fairfax, Virginia from June 12 th to June 18 th and was attended by 65 participants. All of the sessions were plenary sessions accommodating review talks and shorter contributions discussing both theory and recent experiments. At the end of the conference Alan Schwarz summarized and put in context all the presentations of the conference giving a very interesting Summary talk. I want to thank here the Local Organizing Committee that organized the Conference. Many from the University Staff have contributed to the smooth running of the conference. I would like also to thank the Local Scientific Secretariat for their invaluable help in making the conference a truly enjoyable event; a special thanks goes to Maria Hobbs, our local secretary, who worked tirelessly in the organization of every detail. Finally we would like thank the European Organization for Nuclear Research and the George Mason University for their generous support. The next BEACH Conference will be held at Peniche, north of Lisbon, Portugal at the beginning of summer 2018 and I hope that we will all meet again there. (paper)

  6. 25 CFR 36.32 - Standard XII-Graduation requirements for a high school diploma.

    Science.gov (United States)

    2010-04-01

    ...) One-half (1/2) unit in any other social studies; (4) Science—two (2) units. (i) One (1) unit in the general science area. (ii) One (1) unit in laboratory science areas, i.e., chemistry, physics, biology.... Music, art, dance, drama, theatre, and other fine arts courses may be used to satisfy this required unit...

  7. 8. XII avati Tartu Kunstimajas Tartu kunstnike aastalõpunäitus

    Index Scriptorium Estoniae

    2004-01-01

    Esineb 69 kunstnikku 92 teosega. 2004. a. Ado Vabbe visuaalse kunsti preemia - Andrus Kasemaa. Ettevõtlike Daamide Assotsiatsiooni naiskunstnikupreemia - Anne Vasar. Kohvik Wilde preemia - Signe-Fideelia Roots. Kursi koolkonna preemia - Eero Ijavoinen. Rühmituse Üksi Reas preemia - Kaie Luik, Maris Palgi, Malev Toom

  8. L’inspectio di un anonimo investigatore pisano nella prima metà del secolo XII

    Directory of Open Access Journals (Sweden)

    Andrea Puglia

    2013-01-01

    Full Text Available The article examines and publishes in the Appendix a document kept in the Archive of the Archbishop of Pisa, known until now only in a partial transcript, because was for a long time not available. The relevance of this document lies both in its materials and graphics characteristics , but also in its unique content, which presents a cross section of political and social life of the entourage of Bishops in the city and county in the first half of the Twelfth century. In fact, it shows the different sides of an inquest (inspectio conducted in the diocese of Pisa by an anonymous investigator appointed by the Archbishop of Pisa Hubert in 1137. The numerous stages of the inquest were probably recorded in some files and then, with the help of judges (and law experts and the graphic abilities of the episcopal clergy, were written in an entire parchment, with a clear and fluid book-Caroline and with a good rhetoric form. The goals of this document were surely informative, but we don’t exclude also a memorial and judicial objective. In conclusion, the inspectio give us the opportunity of studying the non-epistolographic practices of medieval communication and allows us to know a pragmatic and non-formal system of document building. This system is out of the field of notarial acts with legal effects (chartae and brevia recordationis and different from the writing of judicial records.

  9. 48 CFR 715.370-1 - Title XII selection procedure-general.

    Science.gov (United States)

    2010-10-01

    ... essential, a statement of work, estimate of personnel requirements, special requirements (logistic support... statement of work, an estimate of the personnel required, and special provisions (such as logistic support, government furnished equipment, and so forth), a proposed contract format, and evaluation criteria. No cost...

  10. 18. XII kell 12 kaitstakse EKA E-meedia keskuses 4 magistritööd...

    Index Scriptorium Estoniae

    2002-01-01

    Kristel Sibul "Kehatud kehad - kehad ja identiteet internetis" (juh. Katrin Kivimaa), Ivika Kivi "Virtuaalsed õpitarkvarad" (juh. Mare Emmott Tralla), Maris Lindoja "Digitaalne ruum" (juh. Andres Kurg), Raul Keller "Corporate Consulting in the Digital Age - Jamming vith the Culture" (juh. Richard Barbrook)

  11. Planck early results. XII. Cluster Sunyaev-Zeldovich optical scaling relations

    DEFF Research Database (Denmark)

    Poutanen, T.; Natoli, P.; Polenta, G.

    2011-01-01

    We present the Sunyaev-Zeldovich (SZ) signal-to-richness scaling relation (Y500 - N200) for the MaxBCG cluster catalogue. Employing a multi-frequency matched filter on the Planck sky maps, we measure the SZ signal for each cluster by adapting the filter according to weak-lensing calibrated mass-r...

  12. Planck 2015 results: XII. Full focal plane simulations

    DEFF Research Database (Denmark)

    Ade, P. A R; Aghanim, N.; Arnaud, M.

    2016-01-01

    We present the 8th full focal plane simulation set (FFP8), deployed in support of the Planck 2015 results. FFP8 consists of 10 fiducial mission realizations reduced to 18 144 maps, together with the most massive suite of Monte Carlo realizations of instrument noise and CMB ever generated, compris...

  13. Origen del castillo y coto de Aranga, siglos X-XII

    Directory of Open Access Journals (Sweden)

    Barros, Carlos

    2009-12-01

    Full Text Available The importance of the fortress of the Higth Middle Age in the constitution of the feudal jurisdictions around the year 1000 is illustrated in this work which is the origin of the castle and a lordship of Aranga (now municipality of Galicia from the family of Traba. Th king Alfonso IX of Leon and Galicia transferred in 1193, the domain jurisdiction from a Aranga to Monastery of Sobrado, against the opinion of their vassals and peasants who, in 1168, preferring to continue to belong to the heirs of the counts of Traba and Aranga.

    La importancia de las fortalezas altomedievales en la constitución de las jurisdicciones feudales, en los alrededores del año 1000, se ilustra en este trabajo que trata del origen del castillo y coto de Aranga (actualmente, municipio de Galicia de la casa de Traba. El rey Alfonso IX de León y Galicia traspasa, en 1193, la jurisdicción señorial de Aranga al Monasterio de Sobrado, contra la opinión de sus campesinos y vasallos que, en 1168, preferían seguir perteneciendo a los herederos de los condes de Traba y Aranga.

  14. Nickel-like spectra of elements Y XII to Ag XX from a vacuum spark

    International Nuclear Information System (INIS)

    Schweitzer, N.; Klapisch, M.; Schwob, J.L.; Finkenthal, M.; Bar-Shalom, A.; Mandelbaum, P.

    1980-05-01

    The spectra of elements Y, Zr, Nb, Mo, Ru, Rh, Pd and Ag in the range 10-100 A were obtained from a high power vacuum spark and a grazing incidence high resolution spectrograph. The transitions 3d 10 -3d 9 4p, -3d 9 4f, 3d 9 5p, -3d 9 5f were identified. The agreement with ab initio relativistic calculations is very good. The relevance of jj coupling scheme for level labeling is discussed, as well as the importance of relativistic effects, by comparing with other results on high Z atoms (up to Pt)

  15. Uudised : Baltimaade suurim, XII "Jazzkaar". VII rahvusvaheline koorifestival. Leipzigis improviseeriti edukalt

    Index Scriptorium Estoniae

    2001-01-01

    23.-29. apr. toimuvast festivalist "Jazzkaar 2001". VII rahvusvahelisest koorifestivalist "Tallinn "2001". 6. ja 7. apr. Leipzigis toimunud V rahvusvahelisest improvisatsioonikonkursist, kus osalesid ka eesti interpreedid

  16. 48 CFR Appendix F to Chapter 7 - Use of Collaborative Assistance Method for Title XII Activities

    Science.gov (United States)

    2010-10-01

    .... Such flexibility is also essential to the collaborative style which is responsive to LDC desires in... relationships between host country, USAID and contractor staff to include host country leadership, flexible... leadership and responsibility and the general agreements and budget reached in stage (1). The emphasis here...

  17. Toxicity of 144Ce inhaled in a relatively insoluble form by immature Beagle dogs. XII

    International Nuclear Information System (INIS)

    Boecker, B.B.; Muggenburg, B.A.; Hahn, F.F.; Mauderly, J.L.; McClellan, R.O.

    1983-01-01

    Immature Beagle dogs (3 months old) were exposed once by inhalation to an aerosol of 144 Ce incorporated in fused aluminosilicate particles. The influence of this age on the dose-response relationships is being compared to that of 13-mo-old and 8 to 10.5-yr-old dogs. This study involves 49 dogs that received graded initial lung burdens from 0.004 to 140 μCi 144 Ce/kg body weight and five control dogs. To date, 19 of the 144 Ce-exposed dogs and one of the controls have died. Dogs with the highest initial lung burdens of 144 Ce died during the first 4 months with radiation pneumonitis, pulmonary fibrosis, and congestive heart failure. Pulmonary hemangiosarcoma was the primary finding in dogs that died at 1.5 to 2 years after exposure. Deaths beyond that time have been due primarily to extrapulmonary hemangiosarcomas. Observations are continued on the surviving 30 144 Ce-exposed and four control dogs at 7.0 to 11.2 years after exposure

  18. Coronal emission-line polarization from the statistical equilibrium of magnetic sublevels. I. Fe XII

    International Nuclear Information System (INIS)

    House, L.L.

    1977-01-01

    A general formulation for the polarization of coronal emission lines is presented, and the physics is illustrated through application of the formulation to the lines of Fe XIII at 10747 and 10798 A. The goal is to present a foundation for the determination of the orientation of coronal magnetic fields from emission-line polarization measurements. The physics of emission-line polarization is discussed using the statistical equilibrium equations for the magnetic sublevels of a coronal ion. The formulation of these equations, which describe the polarization of the radiation field in terms of Stokes parameters, is presented; and the various rate parameters: both radiative and collisional: are considered. The emission Stokes vector is constructed from the solution of the equilibrium equations for a point in the corona where the magnetic field has an arbitrary orientation. On the basis of a model, a computer code for the calculation of emission-line polarization is briefly described and illustrated with a number of sample calculations for Fe XIII. Calculations are carried out for three-dimensional models that demonstrate the physics of the formation of emission-line polarization and illustrate how the degree of polarization and angle of polarization and their variations over the corona are related to the density and magnetic field structure. The models considered range from simple cases in which the density distribution with height is spherically symmetric and the field is radial or dipole to a complex case in which both the density and magnetic field distributions are derived from realistic three-dimensional distributions for the 1973 eclipse on the basis of K-coronameter measurements for the density and potential-field extrapolation of surface magnetic fields in the corona

  19. A new species of Gynothemis and its larva (Odonata, Libellulidae) notes on Odonata of Surinam XII

    NARCIS (Netherlands)

    Geijskes, D.C.

    1972-01-01

    The genus Gynothemis was introduced by Calvert (1909), when describing an aberrant member of the Macrothemini from Brazil. The following characteristics were used for this genus: anal area in hind wing with irregularly arranged cells; one row of cells in Rspl, M2 not undulate; triangle in fore wing

  20. Planck intermediate results. XII: Diffuse Galactic components in the Gould Belt System

    DEFF Research Database (Denmark)

    Planck Collaboration,; Ade, P. A. R.; Aghanim, N.

    2013-01-01

    We perform an analysis of the diffuse low-frequency Galactic components in the Southern part of the Gould Belt system (130^\\circ\\leq l\\leq 230^\\circ and -50^\\circ\\leq b\\leq -10^\\circ). Strong ultra-violet (UV) flux coming from the Gould Belt super-association is responsible for bright diffuse...

  1. The VLT-FLAMES Tarantula Survey. XII. Rotational velocities of the single O-type stars

    Science.gov (United States)

    Ramírez-Agudelo, O. H.; Simón-Díaz, S.; Sana, H.; de Koter, A.; Sabín-Sanjulían, C.; de Mink, S. E.; Dufton, P. L.; Gräfener, G.; Evans, C. J.; Herrero, A.; Langer, N.; Lennon, D. J.; Maíz Apellániz, J.; Markova, N.; Najarro, F.; Puls, J.; Taylor, W. D.; Vink, J. S.

    2013-12-01

    Context. The 30 Doradus (30 Dor) region of the Large Magellanic Cloud, also known as the Tarantula nebula, is the nearest starburst region. It contains the richest population of massive stars in the Local Group, and it is thus the best possible laboratory to investigate open questions on the formation and evolution of massive stars. Aims: Using ground-based multi-object optical spectroscopy obtained in the framework of the VLT-FLAMES Tarantula Survey (VFTS), we aim to establish the (projected) rotational velocity distribution for a sample of 216 presumably single O-type stars in 30 Dor. The sample is large enough to obtain statistically significant information and to search for variations among subpopulations - in terms of spectral type, luminosity class, and spatial location - in the field of view. Methods: We measured projected rotational velocities, νesini, by means of a Fourier transform method and a profile fitting method applied to a set of isolated spectral lines. We also used an iterative deconvolution procedure to infer the probability density, P(νe), of the equatorial rotational velocity, νe. Results: The distribution of νesini shows a two-component structure: a peak around 80 kms-1 and a high-velocity tail extending up to ~600 kms-1. This structure is also present in the inferred distribution P(νe) with around 80% of the sample having 0 rate less than 20% of their break-up velocity. For the bulk of the sample, mass loss in a stellar wind and/or envelope expansion is not efficient enough to significantly spin down these stars within the first few Myr of evolution. If massive-star formation results in stars rotating at birth with a large portion of their break-up velocities, an alternative braking mechanism, possibly magnetic fields, is thus required to explain the present-day rotational properties of the O-type stars in 30 Dor. The presence of a sizeable population of fast rotators is compatible with recent population synthesis computations that investigate the influence of binary evolution on the rotation rate of massive stars. Even though we have excluded stars that show significant radial velocity variations, our sample may have remained contaminated by post-interaction binary products. That the high-velocity tail may be populated primarily (and perhaps exclusively) by post-binary interaction products has important implications for the evolutionary origin of systems that produce gamma-ray bursts. Based on observations collected at the European Southern Observatory under program ID 182.D-0222.Full Tables 3 and 4 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/560/A29

  2. Toxicity of 144Ce inhaled in a relatively insoluble form by aged Beagle dogs. XII

    International Nuclear Information System (INIS)

    Boecker, B.B.; Hahn, F.F.; Muggenburg, B.A.; Mauderly, J.L.; McClellan, R.O.; Pickrell, J.A.

    1983-01-01

    The toxicity of relatively insoluble 144 Ce inhaled by 8- to 10.5-year-old Beagle dogs is being investigated to determine possible age-related differences in long-term biological responses. Forty-two dogs were exposed to aerosols of 144 Ce in fused aluminosilicate particles to yield initial lung burdens of 2.2 to 75 μCi 144 Ce/kg body weight, and 12 control dogs were exposed to non-radioactive fused aluminosilicate particles. All 144 Ce-exposed and control dogs have died or were euthanized between 197 and 2726 days after the inhalation exposure. Prominent findings in the 144 Ce-exposed dogs were radiation pneumonitis in 19 of the 23 dogs that died during the first 943 days after exposure, and neoplastic disease in 13 of the 20 dogs that died beyond 904 days after exposure. Pulmonary tumors were found in five of these dogs. In contrast to the study with young adult dogs, in which pulmonary hemangiosarcomas were one of the prominent findings, all of these tumors were carcinomas

  3. The chemistry of cycloheptatriene part XII : the thermal behaviour of substituted cycloheptatrienes : preliminary communication

    NARCIS (Netherlands)

    Borg, ter A.P.; Razenberg, E.; Kloosterziel, H.

    1965-01-01

    cf. CA 63, 457a. The effect of substituents on 1-5 intramol. shifts of H in cycloheptatriene (I) was investigated at 100-140 Deg (CA 59, 14771b). Conversion of 7-substituted I to the 3-substituted isomer was accelerated by all of the substituents studied, including NMe2, OMe, SMe, Me, Ph, and CN,

  4. BANYAN. XII. New Members of Nearby Young Associations from GAIA–Tycho Data

    Science.gov (United States)

    Gagné, Jonathan; Roy-Loubier, Olivier; Faherty, Jacqueline K.; Doyon, René; Malo, Lison

    2018-06-01

    We present a search for stellar members of young associations within 150 pc of the Sun, based on TGAS and an updated version of the BANYAN Σ software to determine Bayesian membership probabilities that includes Gaia–2MASS color-magnitude diagrams. We identify 32 new F0–M3-type bona fide members of the 10–200 Myr old Sco-Cen, Carina, Tucana-Horologium, Columba, and Octans associations and the AB Doradus, β Pictoris, and Carina-Near moving groups. These new bona fide members have measurements of their full kinematics and literature data consistent with a young age. We also confirm the membership of 66 previously known candidate members using their Gaia–Tycho trigonometric distances or new literature radial velocities, and identify 219 additional new candidate members, most of which do not yet have a radial velocity measurement. This work is the first step toward a completeness-corrected survey of young association members based on Gaia DR2 in the near future.

  5. Analysis of judicial demands in health at the Regional Health Department XII

    Directory of Open Access Journals (Sweden)

    Leticia Florido Povinske Domingues

    2017-08-01

    Full Text Available The management of lawsuits in health represents a challenge for most Brazilian municipalities. Many papers described in the literature characterized properly the problem as well as discussed the repercussions on the Unified Health System.In this context, the objective of this study was to analyze the situation of health judicial processes at the twelfth Regional Department in Registro, São Paulo´s state, evaluating the profile of the users who claim in court the couverage of treatment´s costs as well as examination, procedure or medication. For this, we analyzed data on lawsuits in the health field at the twelfth Regional Department in Registro (SP from january 2009 to october 2015.The variables studied were gender, age, municipality of origin of the lawsuit, the mentioned disease, the medical prescription origin, specialty of the prescriber, type of lawsuit triggered, year of the lawsuit, entity judicially triggered and requested items. It was analyzed thirty-eight lawsuits against the twelfth Regional Department, it was observed the prevalence of the female gender, age group above 51 years and originating from the municipality of Registro (SP.The most of the judicial actions are for care given at the Unified Health System, by prescribers of specialty in Clinical Medicine and diagnosed with Diabetes Mellitus. The processes were characterized in the majority by judicial actions called Ordinary Rite, against the State. On the analyzed cases, 92% requested only medications and of these 11% supplements like vitamins and enteral diets.The number of patients who have been served through legal actions in the last three years reached 47% of the total cases registered during the period of the seven years analyzed and the approximate cost was R$ 1,340,000.00.This study contributes to the diagnosis of the processes related to the health judicialization in the region studied. The results showed a predominance of processes which comes from of patients with Diabetes Mellitus which reinforces the emergency needs to discuss public policies able to attend the needs and demands of the community based in the changes generated by the increase of chronic diseases.

  6. Repeated inhalation exposure of Beagle dogs to aerosols of 239PuO2. XII

    International Nuclear Information System (INIS)

    Diel, J.H.; Hahn, F.F.; Muggenburg, B.A.

    1988-01-01

    Beagle dogs were exposed once or semi-annually for 10 yr by inhalation to aerosols of 239 PuO 2 to study the relative doses and effects of these two types of exposures. All exposures have been completed. Dogs exposed at high levels died predominantly of radiation pneumonitis and pulmonary fibrosis. Dogs exposed at lower levels, either once or repeatedly, are dying of a variety of causes including lung cancer. Dogs have survived up to 11 yr after their first exposure. Preliminary results suggest that single and repeated exposures cause similar health effects for equal accumulated radiation doses. (author)

  7. Description of the Earth in the Works of Arabic Geographers from IX to XII Century

    Science.gov (United States)

    Cvijanovic, I.

    2012-12-01

    The works of Arabic writers provide data about shape, position and size of the Earth, planets and zodiac signs. They include preserved maps of Ibn Haukal, Al-Masudi and Al-Idrisi. Al-Masudi (871-956/7) made a map of the world and wrote that the Earth is round, before the Christians in Europe were ready to accept that idea. The famous geographer and cartographer Al-Idrisi (IX/X., died in 903/913.) has lived on the court of Norman king Roger II of Sicily, and after his death on the court of his son William I on Sicily, where he obtained the data from European and Arabic geographers. On the basis of this data he wrote a work known entitled Roger's book. Besides this important work he made a celestial globe and a map of the world in the shape of a silver disk. The lines that marked the borders of seven regions of the inhabited world were engraved on this disk. The Arabs had excellent knowledge of Greek astronomy and accepted their division of the world in seven climatic zones.

  8. EU Interlaboratory comparison study veterinary XII . Bacteriological detection of Salmonella in chicken faeces

    NARCIS (Netherlands)

    Kuijpers AFA; Veenman C; Mooijman KA; LZO

    2009-01-01

    In 2009 heeft een vergelijkende studie onder 34 Nationale Referentie Laboratoria (NRL's) uitgewezen dat alle NRL's in staat waren hoge en lage concentraties Salmonella in kippenmest aan te tonen. Van deze laboratoria lieten er 33 direct zien dat zij het onderzoek met succes en volgens de

  9. Anamnesis de una estructura. La Catedral de Vitoria entre los siglos XII y XX

    Directory of Open Access Journals (Sweden)

    Cámara Muñoz, Leandro

    2002-12-01

    Full Text Available The Cathedral of Vitoria is a building with an extended historical life. We have attempted to produce a chronological sequence of the interventions and architectural “projects” since the beginning of the construction of the church on the early 13th century to the last restorations during the 1960s. This study attempts to fill a void on the available information, crucial for the evaluation of safety and durability issues on the Cathedral. The “anamnesis” practiced on the monument is one of the cornerstones of the method we have chosen for restoration, not only regarding the structural aspects, but regarding the problems of functional interpretation and symbolic content as well. This historical reading the key of structural analysis is what we intend to present: the extraction of the historical building sequence that leads to the current situation of the building, discriminating the different moments of the architectural project, phases of building growth and repair interventions on the structure that comment on or contradict among themselves, to result in the form that we witness now. We use that sequence to evaluate, albeit partially, the safety status of the structure, and to build a working hypothesis for the structural aspects of the restoration tasks.La Catedral de Vitoria es un edificio con una larga vida histórica, llena de acontecimientos constructivos que han venido interesando su comportamiento como estructura construida. Ha sido un objetivo primordial del Plan Director evaluar las sucesivas consecuencias de todos esos acontecimientos y explicar su concatenación. Todo ello se ha investigado durante su redacción, consiguiendo una secuencia cronológica en la que se relaciona el conjunto de intervenciones y de "proyectos" arquitectónicos que se suceden desde el comienzo de la construcción de la iglesia en los inicios del siglo XIII hasta sus últimas restauraciones en los años 60 del siglo XX. Este estudio histórico tiene una aplicación directa en la interpretación de los problemas estructurales que presenta el edificio y viene a llenar un vacío de información fundamental para la evaluación de la seguridad y perdurabilidad actuales de la Catedral. Esa historia de la Catedral viene a ser la recuperación del "historial médico" de un enfermo y puede dar muchas claves sobre los problemas estructurales que en otros apartados del mismo se detallan. La "anamnesis" practicada sobre el monumento es una de las "piedras de toque" del método elegido por nosotros para la restauración del conjunto catedralicio, no sólo en el tema estructural que interesa en esta ponencia sino en todos los problemas de interpretación funcional y contenido simbólico a los que hay que dar solución con las propuestas del restauración. La lectura de esa historia constructiva en clave de análisis estructural es lo que en esta ponencia se presenta: la extracción de la secuencia histórica constructiva que conduce al estado actual del edificio, discriminando los distintos momentos de proyecto arquitectónico, fases de crecimiento constructivo del edificio e intervenciones de reparación de la estructura que se explican o contradicen unos a otros para dar como resultado la torturada forma arquitectónica que nos encontramos ahora. A partir de esa secuencia se evalúa, en parte, el estado de seguridad remanente de la estructura, y se hace una hipótesis de trabajo para las tareas de restauración en esos aspectos estructurales.

  10. In the search for new anticancer drugs XII. Synthesis and biological evaluation of spin labeled nitrosoureas.

    Science.gov (United States)

    Sosnovsky, G; Li, S W

    1985-04-15

    The spin labeled nitrosourea 1-(2-chloroethyl)-3-(1-oxyl-2,2,6,6- tetramethyl-piperidinyl)-1-nitrosourea (SLCNU, 4) and its analogues 5-7 were synthesized either by a regio-selective method or by a conventional route via the nitrosation of the spin labeled intermediates (11a-e). Nitrosation of the ureas 11a-e with dinitrogen tetraoxide resulted in better yields than those obtained with sodium nitrite. The nitrosoureas 4-8 were tested for their anticancer activity against the lymphocytic leukemia P388 in mice. Thus, either at the equal molar dose or at the dose of equal toxicity level, the SLCNU (4) was found to be more active than the clinically used CCNU (1). Unlike CCNU (1) whose LD50 is 56 mg/kg, the SLCNU (4) possesses a low toxicity (LD50 123 mg/kg). Therefore, SLCNU (4) is a promising new entry into the nitrosourea class of anticancer drugs.

  11. Estudiantes y profesores españoles en universidades extranjeras. Siglos XII-XVI

    Directory of Open Access Journals (Sweden)

    Bernabé BARTOLOMÉ MARTÍNEZ

    2010-03-01

    Full Text Available RESUMEN: Dentro de la línea histórico-comparada de este número de la revista, este trabajo pretende ser una elaboración de síntesis. Es un intento de encontrar unidad a algunas investigaciones dispersas que se van publicando sobre el tema. Los cartularios que existen de algunas universidades extranjeras son insuficientes y los libros de registros de estudiantes o de grados no nos han llegado apenas desde las alturas de aquellos siglos xn-xvi. Sin embargo una intensa indagación en los archivos municipales y catedralicios podría arrojar, para este caso, los datos suficientes.

  12. Improvement of laser irradiation uniformity in GEKKO XII glass laser system

    International Nuclear Information System (INIS)

    Miyanaga, Noriaki; Matsuoka, Shinichi; Ando, Akinobu; Amano, Shinji; Nakatsuka, Masahiro; Kanabe, Tadashi; Jitsuno, Takahisa; Nakai, Sadao

    1995-01-01

    The uniform laser irradiation is one of key issues in the direct drive laser fusion research. The several key technologies for the uniform laser irradiation are reported. This paper includes the uniformity performance as a result of the introduction of the random phase plate, the partially coherent light and the beam smoothing by spectral dispersion into the New Gekko XI glass laser system. Finally the authors summarize the overall irradiation uniformity on the spherical target surface by considering the power imbalance effect. The technologies developed for the beam smoothing and the power balance control enable them to achieve the irradiation nonuniformities of around 1% level for a foot pulse and of a few % for a main drive pulse, respectively

  13. Dark-ages reionization and galaxy formation simulation - XII. Bubbles at dawn

    Science.gov (United States)

    Geil, Paul M.; Mutch, Simon J.; Poole, Gregory B.; Duffy, Alan R.; Mesinger, Andrei; Wyithe, J. Stuart B.

    2017-12-01

    The direct detection of regions of ionized hydrogen (H II) has been suggested as a promising probe of cosmic reionization. Observing the redshifted 21-cm signal of hydrogen from the epoch of reionization (EoR) is a key scientific driver behind new-generation, low-frequency radio interferometers. We investigate the feasibility of combining low-frequency observations with the Square Kilometre Array and near infra-red survey data of the Wide-Field Infrared Survey Telescope to detect cosmic reionization by imaging H II bubbles surrounding massive galaxies during the cosmic dawn. While individual bubbles will be too small to be detected, we find that by stacking redshifted 21-cm spectra centred on known galaxies, it will be possible to directly detect the EoR at z ∼ 9-12, and to place qualitative constraints on the evolution of the spin temperature of the intergalactic medium (IGM) at z ≳ 9. In particular, given a detection of ionized bubbles using this technique, it is possible to determine if the IGM surrounding them is typically in absorption or emission. Determining the globally averaged neutral fraction of the IGM using this method will prove more difficult due to degeneracy with the average size of H II regions.

  14. Memória histórica de Cananéia (XII

    Directory of Open Access Journals (Sweden)

    Antônio Paulino de Almeida

    1968-03-01

    Pretendendo Nicolau Dreys, de nacionalidade francesa, obter do govêrno da Província, por Sesmaria, a ilha do Cardoso, e sendo consultada a Câmara de Cananéia, oficiou esta à de Paranaguá em data de 26 de novembro de 1828, prestando as nescessárias informações.

  15. La geometria del còdex 80 (s. XII de la catedral de Tortosa

    Directory of Open Access Journals (Sweden)

    Lluís i Ginovart, Josep

    2015-12-01

    Full Text Available The geometry in codex 80 of the Capitular Archive has traditionally been understood as a complete text and attributed to Gerbert of Aurillac (c. 940-1003. From a new reading of the text, we can say that it is a miscellaneous writing about geometry, composed of three independent parts: one containing the Geometria Incerti Auctoris apocryphical by Gerbert of Aurillac (c. 940-1003; another one is a fragment of De Nuptiis Philologiae et Mercurii by Martianus Capella (fl . 430 from Ergasticis Schematibus of Book VII of the Geometry; and finally there is a gloss to the Elementa by Euclides (c. 325-c. 265 bC. by Al-Ḥajjāj ibn Yūsuf ibn Maṭar (786-833. The interpretation of the geometrical propositions provides knowledge about the indirect measure of places which are inaccessible using medieval instrumental, the astrolabe, mirrors, cane and squares.[ct] La geometria del còdex 80 de l’Arxiu Capitular de Tortosa ha estat tradicionalment atribuïda, com un text únic, a Gerbert d’Orlhac (c. 940-1003. Una nova lectura del text ens permet assegurar que es tracta d’un text de caràcter miscel·lani de geometria, compost per tres textos independents: una part pertany a la Geometria Incerti Auctoris apòcrifa de Gerbert d’Orlhac; una altra, al fragment De Nuptiis Philologiae et Mercurii de Marcià Capella (fl . 430 Ergasticis Schematibus, del llibre VII de la Geometria; i, finalment, s’hi llegeix una glossa als Elementa d’Euclides (c. 325-c. 265 aC. d’Al-Ḥajjāj ibn Yūsuf ibn Maṭar (786-833. La interpretació de les proposicions de la geometria dóna el coneixement de la mesura indirecta de llocs als quals no es pot accedir amb l’instrumental medieval, és a dir, amb astrolabi, miralls, bastons i escaires.

  16. Stereochemical studies of acyclic isoprenoids-XII. Lipids of methanogenic bacteria and possible contributions to sediments

    Science.gov (United States)

    Risatti, J.B.; Rowland, S.J.; Yon, D.A.; Maxwell, J.R.

    1984-01-01

    Abundant volatile lipids of Methanobacterium thermoautotrophicum and Methanosarcina barkeri include isoprenoid hydrocarbons (??? C30), and C15, C20 and C25 isoprenoid alcohols. M. barkeri contains 2,6,10,15,19-pentamethyleicosane, whose relative stereochemistry is the same as found in marine sediments, indicating that it is a marker of methanogenic activity. The C20, C30 and C25 alkenes in M. thermoautotrophicum also have a preferred sterochemistry; the latter have the 2,6,10,14,18-pentamethyleicosanyl skeleton, suggesting that the alkane in marine sediments may derive from methanogens. The stereochemistry of squalane in a marine sediment is also compatible with an origin in methanogens; in contrast, the stereochemistry of pristane in M. thermoautotrophicum indicates a fossil fuel contaminant origin, suggesting that this and certain other alkanes reported in archaebacteria might also be of contaminant origin. There is, therefore, little evidence at present that the pristane in immature marine sediments originates in methanogens. The C15 and C20 saturated alcohols in M. thermoautotrophicum have mainly the all-R configuration. If this is generally true for methanogens, the C20 alcohol in the Messel shale may originate mainly from methanogens, whereas that in the Green River shale may originate mainly from photosynthetic organisms. ?? 1984.

  17. CHIANTI—AN ATOMIC DATABASE FOR EMISSION LINES. XII. VERSION 7 OF THE DATABASE

    International Nuclear Information System (INIS)

    Landi, E.; Del Zanna, G.; Mason, H. E.; Young, P. R.; Dere, K. P.

    2012-01-01

    The CHIANTI spectral code consists of an atomic database and a suite of computer programs to calculate the optically thin spectrum of astrophysical objects and carry out spectroscopic plasma diagnostics. The database includes atomic energy levels, wavelengths, radiative transition probabilities, collision excitation rate coefficients, and ionization and recombination rate coefficients, as well as data to calculate free-free, free-bound, and two-photon continuum emission. Version 7 has been released, which includes several new ions, significant updates to existing ions, as well as Chianti-Py, the implementation of CHIANTI software in the Python programming language. All data and programs are freely available at http://www.chiantidatabase.org, while the Python interface to CHIANTI can be found at http://chiantipy.sourceforge.net.

  18. CHIANTI-AN ATOMIC DATABASE FOR EMISSION LINES. XII. VERSION 7 OF THE DATABASE

    Energy Technology Data Exchange (ETDEWEB)

    Landi, E. [Department of Atmospheric, Oceanic and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Del Zanna, G.; Mason, H. E. [Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA (United Kingdom); Young, P. R. [College of Science, George Mason University, 4400 University Drive, Fairfax, VA, 22030 (United States); Dere, K. P. [School of Physics, Astronomy and Computational Sciences, MS 6A2, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States)

    2012-01-10

    The CHIANTI spectral code consists of an atomic database and a suite of computer programs to calculate the optically thin spectrum of astrophysical objects and carry out spectroscopic plasma diagnostics. The database includes atomic energy levels, wavelengths, radiative transition probabilities, collision excitation rate coefficients, and ionization and recombination rate coefficients, as well as data to calculate free-free, free-bound, and two-photon continuum emission. Version 7 has been released, which includes several new ions, significant updates to existing ions, as well as Chianti-Py, the implementation of CHIANTI software in the Python programming language. All data and programs are freely available at http://www.chiantidatabase.org, while the Python interface to CHIANTI can be found at http://chiantipy.sourceforge.net.

  19. Soil Properties Database of Spanish Soils. Volume XII.- Castilla-Leon (c): Burgos, Soria and Segovia

    International Nuclear Information System (INIS)

    Trueba, C; Millan, R.; Schmid, T.; Lago, C.; Roquero, C; Magister, M.

    1999-01-01

    The soil vulnerability determines the sensitivity of the soil after an accidental radioactive contamination due to Cs-137 and Sr-90. The Departamento de Impacto Ambiental de la Energia of CIEMAT is carrying out an assessment of the radiological vulnerability of the different Spanish soils found on the Iberian Peninsula. This requires the knowledge of the soil properties for the various types of existing soils. In order to achieve this aim, a bibliographical compilation of soil profiles has been made to characterize the different soil types and create a database of their properties. Depending on the year of publication and the type of documentary source, the information compiled from the available bibliography is very heterogeneous. Therefore, an important effort has been made to normalize and process the information prior to its incorporation to the database. This volume presents the criteria applied to normalize and process the data as well as the soil properties of the various soil types belonging to the provinces of Burgos, Soria and Segovia of the Comunidad Autonoma de Castilla-Leon. (Author) 36 refs

  20. WAED-HP-103, Health Physics Manual, Revision XII, March 1981. Final report

    International Nuclear Information System (INIS)

    1982-01-01

    The project scope of work included the complete decontamination and decommissioning (D and D) of the Westinghouse ARD Fuel Laboratories at the Cheswick Site in the shortest possible time. This has been accomplished in the following four phases: (1) preparation of documents and necessary paperwork; packaging and shipping of all special nuclear materials in an acceptable form to a reprocessing agency; (2) decontamination of all facilities, glove boxes and equipment; loading of generated waste into bins, barrels and strong wooden boxes; (3) shipping of all bins, barrels and boxes containing waste to the designated burial site; removal of all utility services from the laboratories; (4) final survey of remaining facilities and certification for nonrestricted use; preparation of final report. This attachment describes the responsibilities, standards, practices and procedures for radiaton protection and safety in the facilities of the Westinghouse Electric Corporation at Cheswick, Pennsylvania. In addition to the application of these standards and procedures, there is continual surveillance of the operations, equipment, and personnel to detect and correct any conditions which might create a health or accident hazard

  1. Activation of 125I-Factor IX and 125I-Factor X: Effect of tissue factor and Factor VII, Factor Xsub(a) and thrombin

    International Nuclear Information System (INIS)

    Oesterud, B.; Rapaport, S.I.

    Activation of Factor IX and Factor X was studied by adding 125 I-Factor IX or 125 I-Factor X to reaction mixtures and quantitating cleavage products by reduced sodium dodecylsulfate gel electrophoresis. Thrombin failed to activate Factors IX or X; Factor Xsub(a) produced insignificant amounts of cleavage products of both factors. In contrast, the reaction product of tissue factor and Factor VII cleaved large amounts of both Factor IX and Factor X in purified systems and in plasma. In incubation mixtures of plasma containing added 125 I-Factor IX or 125 I-Factor X, tissue factor and Ca 2+ ions, the percentage of total radioactivity in the heavy chain peak of 125 I-IXsub(a) and the heavy chain of 125 I-Xsub(a) increased at a similar rate. When the tissue factor was diluted, similar curves were obtained for percent cleavage of 125 I-Factor IX and percent cleavage of 125 I-Factor X plotted against tissue factor concentration. These findings support the hypothesis that activation of Factor IX by the tissue factor-Factor VII reaction product represents a physiologically significant step in normal haemostasis. (author)

  2. Psychosomatic factors in pruritus.

    Science.gov (United States)

    Tey, Hong Liang; Wallengren, Joanna; Yosipovitch, Gil

    2013-01-01

    Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors, mirtazapine, tricyclic antidepressants (amitriptyline and doxepin), and anticonvulsants (gabapentin, pregabalin); the role of neurokinin receptor-1 antagonists awaits verification. Antipsychotics are required for treating itch and formication associated with schizophrenia and delusion of parasitosis (including Morgellons disease). Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Factorization of Observables

    Science.gov (United States)

    Eliaš, Peter; Frič, Roman

    2017-12-01

    Categorical approach to probability leads to better understanding of basic notions and constructions in generalized (fuzzy, operational, quantum) probability, where observables—dual notions to generalized random variables (statistical maps)—play a major role. First, to avoid inconsistencies, we introduce three categories L, S, and P, the objects and morphisms of which correspond to basic notions of fuzzy probability theory and operational probability theory, and describe their relationships. To illustrate the advantages of categorical approach, we show that two categorical constructions involving observables (related to the representation of generalized random variables via products, or smearing of sharp observables, respectively) can be described as factorizing a morphism into composition of two morphisms having desired properties. We close with a remark concerning products.

  4. Functional Maximum Autocorrelation Factors

    DEFF Research Database (Denmark)

    Larsen, Rasmus; Nielsen, Allan Aasbjerg

    2005-01-01

    MAF outperforms the functional PCA in concentrating the interesting' spectra/shape variation in one end of the eigenvalue spectrum and allows for easier interpretation of effects. Conclusions. Functional MAF analysis is a useful methods for extracting low dimensional models of temporally or spatially......Purpose. We aim at data where samples of an underlying function are observed in a spatial or temporal layout. Examples of underlying functions are reflectance spectra and biological shapes. We apply functional models based on smoothing splines and generalize the functional PCA in......\\verb+~+\\$\\backslash\\$cite{ramsay97} to functional maximum autocorrelation factors (MAF)\\verb+~+\\$\\backslash\\$cite{switzer85,larsen2001d}. We apply the method to biological shapes as well as reflectance spectra. {\\$\\backslash\\$bf Methods}. MAF seeks linear combination of the original variables that maximize autocorrelation between...

  5. Pion form factor

    Energy Technology Data Exchange (ETDEWEB)

    Ryong Ji, C.; Pang, A.; Szczepaniak, A. [North Carolina State Univ., Raleigh, NC (United States)

    1994-04-01

    It is pointed out that the correct criterion to define the legal PQCD contribution to the exclusive processes in the lightcone perturbative expansion should be based on the large off-shellness of the lightcone energy in the intermediate states. In the lightcone perturbative QCD calculation of the pion form factor, the authors find that the legal PQCD contribution defined by the lightcone energy cut saturates in the smaller Q{sup 2} region compared to that defined by the gluon four-momentum square cut. This is due to the contribution by the highly off-energy-shell gluons in the end point regions of the phase space, indicating that the gluon four-momentum-square cut may have cut too much to define the legal PQCD.

  6. Eukaryotic transcription factors

    DEFF Research Database (Denmark)

    Staby, Lasse; O'Shea, Charlotte; Willemoës, Martin

    2017-01-01

    Gene-specific transcription factors (TFs) are key regulatory components of signaling pathways, controlling, for example, cell growth, development, and stress responses. Their biological functions are determined by their molecular structures, as exemplified by their structured DNA-binding domains...... regions with function-related, short sequence motifs and molecular recognition features with structural propensities. This review focuses on molecular aspects of TFs, which represent paradigms of ID-related features. Through specific examples, we review how the ID-associated flexibility of TFs enables....... It is furthermore emphasized how classic biochemical concepts like allostery, conformational selection, induced fit, and feedback regulation are undergoing a revival with the appreciation of ID. The review also describes the most recent advances based on computational simulations of ID-based interaction mechanisms...

  7. Nucleon Electromagnetic Form Factors

    Energy Technology Data Exchange (ETDEWEB)

    Marc Vanderhaeghen; Charles Perdrisat; Vina Punjabi

    2007-10-01

    There has been much activity in the measurement of the elastic electromagnetic proton and neutron form factors in the last decade, and the quality of the data has greatly improved by performing double polarization experiments, in comparison with previous unpolarized data. Here we review the experimental data base in view of the new results for the proton, and neutron, obtained at JLab, MAMI, and MIT-Bates. The rapid evolution of phenomenological models triggered by these high-precision experiments will be discussed, including the recent progress in the determination of the valence quark generalized parton distributions of the nucleon, as well as the steady rate of improvements made in the lattice QCD calculations.

  8. Wave friction factor rediscovered

    Science.gov (United States)

    Le Roux, J. P.

    2012-02-01

    The wave friction factor is commonly expressed as a function of the horizontal water particle semi-excursion ( A wb) at the top of the boundary layer. A wb, in turn, is normally derived from linear wave theory by {{U_{{wb}}/T_{{w}}}}{{2π }} , where U wb is the maximum water particle velocity measured at the top of the boundary layer and T w is the wave period. However, it is shown here that A wb determined in this way deviates drastically from its real value under both linear and non-linear waves. Three equations for smooth, transitional and rough boundary conditions, respectively, are proposed to solve this problem, all three being a function of U wb, T w, and δ, the thickness of the boundary layer. Because these variables can be determined theoretically for any bottom slope and water depth using the deepwater wave conditions, there is no need to physically measure them. Although differing substantially from many modern attempts to define the wave friction factor, the results coincide with equations proposed in the 1960s for either smooth or rough boundary conditions. The findings also confirm that the long-held notion of circular water particle motion down to the bottom in deepwater conditions is erroneous, the motion in fact being circular at the surface and elliptical at depth in both deep and shallow water conditions, with only horizontal motion at the top of the boundary layer. The new equations are incorporated in an updated version (WAVECALC II) of the Excel program published earlier in this journal by Le Roux et al. Geo-Mar Lett 30(5): 549-560, (2010).

  9. [The Steel factor].

    Science.gov (United States)

    Cáceres-Cortés, J R

    1997-01-01

    Mice bearing mutations at either of two loci, dominant White spotting(W) or Steel(Sl), exhibit development defects in hematopoietic, melanocytic and germ cells. Genetics studies have shown that the SI locus encodes the Steel factor (SF), which is the ligand for the tyrosine kinase receptor c-kit, the product of the W locus. SF is synthesized in membrane-bound form and can be processed to produce a soluble form. Cell-cell interaction is important in the production of normal blood cells in vivo and in vitro and in the cellular expansion of leukemic cells. We discuss here how SF decreases the requirements in cell interaction for blast colony formation in acute myeloblastic leukemia (AML) and the presence of membrane-bound SF possibly contributes to the density-dependent growth of the AML blasts. We explain that SF is mainly a survival factor for hematopoietic cells, of little proliferative effect, which maintains CD34+ hematopoietic cells in an undifferentiated state. These properties would potentially allow the maintenance of hematopoietic cells in culture for the purpose of marrow purging or gene therapy. The activation of the c-kit signal transduction pathway may play a significant role in the development of many types of non-hematological malignancies by disrupting normal cell-cell interactions and allowing the growth of cancer cell populations. In summary, the properties of the SF indicate it has a role for survival signals during the process of normal differentiation, AML proliferation and in the maintenance of many c-kit+ tumors.

  10. Neutron quality factor

    International Nuclear Information System (INIS)

    1995-06-01

    Both the International Commission on Radiological Protection (ICRP) and the National Council on Radiation Protection and Measurements (NCRP) have recommended that the radiation quality weighting factor for neutrons (Q n , or the corresponding new modifying factor, w R ) be increased by a value of two for most radiation protection practices. This means an increase in the recommended value for Q n from a nominal value of 10 to a nominal value of 20. This increase may be interpreted to mean that the biological effectiveness of neutrons is two times greater than previously thought. A decision to increase the value of Q n will have a major impact on the regulations and radiation protection programs of Federal agencies responsible for the protection of radiation workers. Therefore, the purposes of this report are: (1) to examine the general concept of open-quotes quality factorclose quotes (Q) in radiation protection and the rationale for the selection of specific values of Q n ; and (2) to make such recommendations to the Federal agencies, as appropriate. This report is not intended to be an exhaustive review of the scientific literature on the biological effects of neutrons, with the aim of defending a particular value for Q n . Rather, the working group examined the technical issues surrounding the current recommendations of scientific advisory bodies on this matter, with the aim of determining if these recommendations should be adopted by the Federal agencies. Ultimately, the group concluded that there was no compelling basis for a change in Q n . The report was prepared by Federal scientists working under the auspices of the Science Panel of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC)

  11. Hypercoagulability and the risk of myocardial infarction and ischemic stroke in young women.

    Science.gov (United States)

    Siegerink, B; Maino, A; Algra, A; Rosendaal, F R

    2015-09-01

    Myocardial infarction (MI) and ischemic stroke (IS) are acute forms of arterial thrombosis and share some, but not all, risk factors, indicating different pathophysiological mechanisms. This study aims to determine if hypercoagulability has a differential effect on the risk of MI and IS. We reviewed the results from the Risk of Arterial Thrombosis in Relation to Oral Contraceptives study, a population-based case-control study involving young women ( 1; for 12 (41%), it was > 2; and for 5 (17%), it was > 2.75. The five risk factors with the largest differences in associations were high levels of activated factor XI (FXI) and FXII, kallikrein, the presence of lupus anticoagulans, and a genetic variation in the FXIII gene. In young women, prothrombotic factors are associated more with the risk of IS than with MI risk, suggesting a different role of hypercoagulability in the mechanism leading to these two diseases. © 2015 International Society on Thrombosis and Haemostasis.

  12. Factorization and non-factorization in diffractive hard scattering

    International Nuclear Information System (INIS)

    Berera, Arjun

    1997-01-01

    Factorization, in the sense defined for inclusive hard scattering, is discussed for diffractive hard scattering. A factorization theorem similar to its inclusive counterpart is presented for diffractive DIS. For hadron-hadron diffractive hard scattering, in contrast to its inclusive counterpart, the expected breakdown of factorization is discussed. Cross section estimates are given from a simple field theory model for non-factorizing double-pomeron-exchange (DPE) dijet production with and without account for Sudakov suppression

  13. Robust and Sparse Factor Modelling

    DEFF Research Database (Denmark)

    Croux, Christophe; Exterkate, Peter

    Factor construction methods are widely used to summarize a large panel of variables by means of a relatively small number of representative factors. We propose a novel factor construction procedure that enjoys the properties of robustness to outliers and of sparsity; that is, having relatively few...... nonzero factor loadings. Compared to the traditional factor construction method, we find that this procedure leads to a favorable forecasting performance in the presence of outliers and to better interpretable factors. We investigate the performance of the method in a Monte Carlo experiment...

  14. Identifying the important factors in simulation models with many factors

    NARCIS (Netherlands)

    Bettonvil, B.; Kleijnen, J.P.C.

    1994-01-01

    Simulation models may have many parameters and input variables (together called factors), while only a few factors are really important (parsimony principle). For such models this paper presents an effective and efficient screening technique to identify and estimate those important factors. The

  15. External Factors, Internal Factors and Self-Directed Learning Readiness

    Science.gov (United States)

    Ramli, Nurjannah; Muljono, Pudji; Afendi, Farit M.

    2018-01-01

    There are many factors which affect the level of self-directed learning readiness. This study aims to investigate the relationship between external factors, internal factors and self-directed learning readiness. This study was carried out by using a census method for fourth year students of medical program of Tadulako University. Data were…

  16. Electromagnetic Hadronic Form-Factors

    International Nuclear Information System (INIS)

    Edwards, Robert G.

    2005-01-01

    We present a calculation of the nucleon electromagnetic form-factors as well as the pion and rho to pion transition form-factors in a hybrid calculation with domain wall valence quarks and improved staggered (Asqtad) sea quarks

  17. R-Factor for Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The rainfall-runoff erosivity factor (R-Factor) quantifies the effects of raindrop impacts and reflects the amount and rate of runoff associated with the rain. The...

  18. Air Emissions Factors and Quantification

    Science.gov (United States)

    Emissions factors are used in developing air emissions inventories for air quality management decisions and in developing emissions control strategies. This area provides technical information on and support for the use of emissions factors.

  19. Integrated Factors Correlating Undergraduate Academic ...

    African Journals Online (AJOL)

    Integrated Factors Correlating Undergraduate Academic Achievement in Bayelsa State, Nigeria. ... AFRREV IJAH: An International Journal of Arts and Humanities ... Thus, it is study investigated the integrated factors determining academic performance of students in public secondary schools in Bayelsa State, Nigeria.

  20. Human Factors in Training

    Science.gov (United States)

    Barshi, Immanuel; Byrne, Vicky; Arsintescu, Lucia; Connell, Erin

    2010-01-01

    Future space missions will be significantly longer than current shuttle missions and new systems will be more complex than current systems. Increasing communication delays between crews and Earth-based support means that astronauts need to be prepared to handle the unexpected on their own. As crews become more autonomous, their potential span of control and required expertise must grow to match their autonomy. It is not possible to train for every eventuality ahead of time on the ground, or to maintain trained skills across long intervals of disuse. To adequately prepare NASA personnel for these challenges, new training approaches, methodologies, and tools are required. This research project aims at developing these training capabilities. By researching established training principles, examining future needs, and by using current practices in space flight training as test beds, both in Flight Controller and Crew Medical domains, this research project is mitigating program risks and generating templates and requirements to meet future training needs. Training efforts in Fiscal Year 09 (FY09) strongly focused on crew medical training, but also began exploring how Space Flight Resource Management training for Mission Operations Directorate (MOD) Flight Controllers could be integrated with systems training for optimal Mission Control Center (MCC) operations. The Training Task addresses Program risks that lie at the intersection of the following three risks identified by the Project: 1) Risk associated with poor task design; 2) Risk of error due to inadequate information; and 3) Risk associated with reduced safety and efficiency due to poor human factors design.

  1. Self-shielding factors

    International Nuclear Information System (INIS)

    Kaul, D.C.

    1982-01-01

    Throughout the last two decades many efforts have been made to estimate the effect of body self-shielding on organ doses from externally incident neutrons and gamma rays. These began with the use of simple geometry phantoms and have culminated in the use of detailed anthropomorphic phantoms. In a recent effort, adjoint Monte Carlo analysis techniques have been used to determine dose and dose equivalent to the active marrow as a function of energy and angle of neutron fluence externally incident on an anthropomorphic phantom. When combined with fluences from actual nuclear devices, these dose-to-fluence factors result in marrow dose values that demonstrate great sensitivity to variations in device type, range, and body orientation. Under a state-of-the-art radiation transport analysis demonstration program for the Japanese cities, sponsored by the Defense Nuclear Agency at the request of the National Council on Radiation Protection and Measurements, the marrow dose study referred to above is being repeated to obtain spectral distributions within the marrow for externally incident neutrons and gamma rays of arbitrary energy and angle. This is intended to allow radiobiologists and epidemiologists to select and to modify numbers of merit for correlation with health effects and to permit a greater understanding of the relationship between human and laboratory subject dosimetry

  2. Research organizational factors

    International Nuclear Information System (INIS)

    Coffman, F.D. Jr.

    1990-01-01

    Organizational processes at nuclear power plants should be sufficient to prevent accidents and to protect public health and safety upon the occurrence of an accident. The role of regulatory research is to confirm that agency assessments of organization processes are on a firm technical basis and provide for improvements in the NRC [Nuclear Regulatory Commission] programs. A firm technical basis is achieved by reducing uncertainties associated with methods and measures used to assess organization processes. The general objective for regulatory research is to confirm that the agency has a coherent understanding of the organizational processes that are individually necessary and are collectively sufficient for safe operations, methods are available to reliably characterize organizational processes, and measures exist to monitor changes in the key organizational processes. The first specific objective was to develop a method to translate organizational processes into PRAs. The discussion provides feedback and insights from experience with the past and the ongoing organizational factors research. That experience suggests a set of ingredients that appear proper for performing regulatory research on organizational processes. By keeping focused upon these proper ingredients, the research will contribute to the regulatory assessments of utility management through the use of improved methods and measures in investigations, inspections, diagnostics, performance indicators, and PRA insights

  3. BASIC FACTORS OF MARKET CONCENTRATION

    OpenAIRE

    V. Fyliuk

    2013-01-01

    The paper systemizes factors which reinforce trends towards market concentration in all economic systems. These factors include factors related to the general changes in economic environment such as globalization of the world economy, state structural and taxation policies, cycle of economic development and changes in consumer demand. They also include factors related to competition (intensification of competition, companies’ desire to monopolize market and present market structure) and scien...

  4. Human Factors in Marine Casualties

    Directory of Open Access Journals (Sweden)

    Jelenko Švetak

    2002-05-01

    Full Text Available Human factors play an important role in the origin of accidents,and it is commonly claimed that between seventy andninety-five percent of industrial and transport accidents involvehuman factors, see Figure 1.Some authorities, however, claim that ultimately, all accidentsinvolve human factors.

  5. Risks factoring business: accounting measurement

    Directory of Open Access Journals (Sweden)

    Z.V. Gutsaylyuk

    2015-06-01

    Full Text Available The paper carried out the identification of risk factors for the development of possible accounting software management. Studied theoretical and methodological aspects of the risk classification of factoring operations in the part of the risk assessment factors. It is proposed to consider the risks factors as the risk that is acceptable controlled by accounting instruments and the risks that can not be taken into account in the accounting records. To minimize the risk factor, accounting-driven tools, a method of self-insurance, which is a factor in the creation of provision for factoring transactions designed to cover unexpected expenses and losses. Provision for factoring factor will establish more stable conditions of financial activity and avoid the fluctuations of profit factor in relation to the writing off of losses on factoring operatsіyam.Developed proposals allow for further research to improve the organizational and methodological basis of accounting and analysis of information as a basis for providing risk management factor, particularly in terms of improving the evaluation questions such risks and their qualitative and quantitative analysis.

  6. Investing in systematic factor premiums

    NARCIS (Netherlands)

    Koedijk, Kees G.; Slager, Alfred M. H.; Stork, P.A.

    In this paper we investigate and evaluate factor investing in the US and Europe for equities and bonds. We show that factor-based portfolios generally produce comparable or better portfolios than market indices. We expand the analysis to other asset classes and factors, work with other optimisation

  7. Sparse and Robust Factor Modelling

    NARCIS (Netherlands)

    C. Croux (Christophe); P. Exterkate (Peter)

    2011-01-01

    textabstractFactor construction methods are widely used to summarize a large panel of variables by means of a relatively small number of representative factors. We propose a novel factor construction procedure that enjoys the properties of robustness to outliers and of sparsity; that is, having

  8. Risk Factor Assessment Branch (RFAB)

    Science.gov (United States)

    The Risk Factor Assessment Branch (RFAB) focuses on the development, evaluation, and dissemination of high-quality risk factor metrics, methods, tools, technologies, and resources for use across the cancer research continuum, and the assessment of cancer-related risk factors in the population.

  9. Geriatic Disability Related Factors

    Directory of Open Access Journals (Sweden)

    Mohsen Adib Hajbagheri

    2008-07-01

    Full Text Available Objectives: Reports are indicating of increasing trend of aging and disability in the developing countries while such disabilities are decreasing within the developed countries. This study designed to evaluate the disability and some of its related factors among the elderly population (65 and older in Kashan, Iran. Methods & Materials: A cross-sectional analytical study was conducted on a multi-stage random sample of 350 elderly people (65 year and older in Kashan. The WHO-DAS-II was used as the generic disability measure. The questionnair had 48 questions. The range of score could be between 0-144. Chi-square, t-test analysis and ANOVA were utilized to check significant differences between subgroups. Results: 61% were men and 12% were living lonely. One fourth had some type of addiction, the majority were ilitrate and two thired had not regular phisycal activity.Twenty percent of the old people had a modereate disability and 4.3% were extremely disabled. A significant relationship was found between the disability and variables such as sex, age, living style, needing help, marriage status, living location, addiction, job, level of physical activity, education, and having multiple diseases. Conclusion: In conclusion, geriatric population in Iran, has a lower levels of disability in compare to those of other developed countries. Need of geriatric cares must be be increasing, since the populationpattern of elderly people is increasing in Iran. Female and ilitrate elders were sufering of more disability. These findings indicated the nessesity to more attention to these voulnarable subgroups of population.

  10. Gut transfer factors

    International Nuclear Information System (INIS)

    1990-01-01

    A Nuclear Energy Agency (NEA) Expert Group has proposed values for the absorbed fractions (f 1 values) of radionuclides ingested in food and drinking water by members of the public. The f 1 values for adults, which are also taken to apply to children from 1 year of age, are increased from those given in ICRP Publication 30 for occupationally exposed adults for 7 elements out of the 31 considered. Since the publication of the NEA report, further information has become available that is relevant to the choice of f 1 values for polonium and thorium. These data suggest that for the present the f 1 value for polonium currently recommended by ICRP (0.1) should be retained, and that for thorium a reasonable f 1 value is 0.0005. With these exceptions, the NRPB endorses the revisions in f 1 values proposed by the NEA Expert Group for adults and children from 1 year of age. Higher f 1 values are proposed by the NEA expert Group for absorption in the first year of life. For adult values of between 0.01 and 0.5, an increase by a factor of two is assumed, and for adult values of 0.001 or less, absorption by infants is taken to be ten times greater. This approach is consistent with, and extends, that applied to the actinides in ICRP Publication 48 and represents a reasonable interpretation of current evidence. The NRPB therefore endorses the approach proposed by the NEA Expert Group for the calculation of doses to infants. (author)

  11. Risk factors for indications of intraoperative blood transfusion among patients undergoing surgical treatment for colorectal adenocarcinoma Fatores de risco para indicação de transfusão sanguínea intraoperatória em doentes operados por adenocarcinoma colorretal

    Directory of Open Access Journals (Sweden)

    Iara Gonçalves

    2009-09-01

    Full Text Available CONTEXT: Identification of risk factors for requiring transfusions during surgery for colorectal cancer may lead to preventive actions or alternative measures, towards decreasing the use of blood components in these procedures, and also rationalization of resources use in hemotherapy services. This was a retrospective case-control study using data from 383 patients who were treated surgically for colorectal adenocarcinoma at "Fundação Pio XII", in Barretos-SP, Brazil, between 1999 and 2003. OBJECTIVE: To recognize significant risk factors for requiring intraoperative blood transfusion in colorectal cancer surgical procedures. METHODS: Univariate analyses were performed using Fisher's exact test or the chi-squared test for dichotomous variables and Student's t test for continuous variables, followed by multivariate analysis using multiple logistic regression. RESULTS: In the univariate analyses, height (P = 0.06, glycemia (P = 0.05, previous abdominal or pelvic surgery (P = 0.031, abdominoperineal surgery (POBJETIVO: Identificar fatores de risco de indicação de transfusão sanguínea intraoperatória em doentes submetidos a tratamento cirúrgico por adenocarcinoma colorretal. MÉTODOS: Estudo retrospectivo, tipo caso-controle, realizado na Fundação Pio XII, em Barretos, SP, utilizando-se base de dados de prontuários de 383 pacientes admitidos entre 1999 e 2003. Utilizou-se teste exato de Fischer ou qui ao quadrado para variáveis dicotômicas e t de Student para variáveis contínuas, na análise univariada, adotando-se nível de significância de 10% (P<0,10; na análise multivariada foi aplicado o teste de regressão logística múltipla, com nível de significância de 5% (P<0,05; as razões de chances e os respectivos intervalos de confiança de 95% foram calculados. RESULTADOS: Nas análises univariadas foram consideradas significantes as variáveis altura (P = 0,06, glicemia (P = 0,05, antecedente de cirurgia abdominal ou pélvica (P

  12. Factors Affecting Medical Service Quality.

    Science.gov (United States)

    Mosadeghrad, Ali Mohammad

    2014-02-01

    A better understanding of factors influencing quality of medical service can pinpoint better strategies for quality assurance in medical services. This study aimed to identify factors affecting the quality of medical services provided by Iranian physicians. Exploratory in-depth individual interviews were conducted with sixty-four physicians working in various medical institutions in Iran. Individual, organizational and environmental factors enhance or inhibit the quality of medical services. Quality of medical services depends on the personal factors of the physician and patient, and factors pertaining to the healthcare setting and the broader environment. Differences in internal and external factors such as availability of resources, patient cooperation and collaboration among providers affect the quality of medical services and patient outcomes. Supportive leadership, proper planning, education and training and effective management of resources and processes improve the quality of medical services. This article contributes to healthcare theory and practice by developing a conceptual framework for understanding factors that influence medical services quality.

  13. Prognostic factors of breast cancer

    International Nuclear Information System (INIS)

    Gonzalez Ortega, Jose Maria; Morales Wong, Mario Miguel; Lopez Cuevas, Zoraida; Diaz Valdez, Marilin

    2011-01-01

    The prognostic factors must to be differentiated of the predictive ones. A prognostic factor is any measurement used at moment of the surgery correlated with the free interval of disease or global survival in the absence of the systemic adjuvant treatment and as result is able to correlate with the natural history of the disease. In contrast, a predictive factor is any measurement associated with the response to a given treatment. Among the prognostic factors of the breast cancer are included the clinical, histological, biological, genetic and psychosocial factors. In present review of psychosocial prognostic factors has been demonstrated that the stress and the depression are negative prognostic factors in patients presenting with breast cancer. It is essential to remember that the assessment of just one prognostic parameter is a help but it is not useful to clinical and therapeutic management of the patient.(author)

  14. The population factor.

    Science.gov (United States)

    Kats, G

    1983-01-01

    Reducing population growth is essentil to Egypt's broader efforts to improve facilities, services, and the phsycial quality of life. Although a family planning program has existed since the mid-1950s, the 2.7% annual rate of population growth has not changed in 30 years. Nasser and the other "free officers" who seized power in 1952 became concerned about the adverse effects of the rapidly growing population, but perhaps out of concern with a possible religious backlash, they confined themselves to launching studies and subsidizing several dozen private family planning clinics. From 1962-72, the number of private clinics grew from 28 to 480, and family planning was introduced in government healthclinics in 1965. Such clinics are mainly located in rural areas and are staffed by doctors and other personnel who are not members of the local community and are not very effective at promoting family planning. Local girls and women called Rayadet were recruited to promote the idea to birth control in local communities. By 1970, 12.6% of Egyptians were using reliable contraception. A national survey 12 years later found 34% using contraception, buth the figure seems high. Approximately 60-65% of eligible couples would need to practice birth control for Egypt to reach a less than 1% annuel increase. The Egyptian government hopes to slow population growth to 1% by the year 2000, but major problems of motivation remain especially among the rural poor. Several factors may lead to success of the family planning effort: 1) financial and technical support from international family planning sources has grown rapidley and is likely to remain high; 2) the mortality rate has dropped from 17.8/1000 in 1952 to about half that level, while the rate of natural increase is about the same, suggesting that future reductions in the birth rate will translate to a reduced rate of natural increase, and that parents will be less reluctant to practice faimly planning if there is a greater chance

  15. A factor analysis to detect factors influencing building national brand

    Directory of Open Access Journals (Sweden)

    Naser Azad

    Full Text Available Developing a national brand is one of the most important issues for development of a brand. In this study, we present factor analysis to detect the most important factors in building a national brand. The proposed study uses factor analysis to extract the most influencing factors and the sample size has been chosen from two major auto makers in Iran called Iran Khodro and Saipa. The questionnaire was designed in Likert scale and distributed among 235 experts. Cronbach alpha is calculated as 84%, which is well above the minimum desirable limit of 0.70. The implementation of factor analysis provides six factors including “cultural image of customers”, “exciting characteristics”, “competitive pricing strategies”, “perception image” and “previous perceptions”.

  16. Risk factors for stress fractures.

    Science.gov (United States)

    Bennell, K; Matheson, G; Meeuwisse, W; Brukner, P

    1999-08-01

    Preventing stress fractures requires knowledge of the risk factors that predispose to this injury. The aetiology of stress fractures is multifactorial, but methodological limitations and expediency often lead to research study designs that evaluate individual risk factors. Intrinsic risk factors include mechanical factors such as bone density, skeletal alignment and body size and composition, physiological factors such as bone turnover rate, flexibility, and muscular strength and endurance, as well as hormonal and nutritional factors. Extrinsic risk factors include mechanical factors such as surface, footwear and external loading as well as physical training parameters. Psychological traits may also play a role in increasing stress fracture risk. Equally important to these types of analyses of individual risk factors is the integration of information to produce a composite picture of risk. The purpose of this paper is to critically appraise the existing literature by evaluating study design and quality, in order to provide a current synopsis of the known scientific information related to stress fracture risk factors. The literature is not fully complete with well conducted studies on this topic, but a great deal of information has accumulated over the past 20 years. Although stress fractures result from repeated loading, the exact contribution of training factors (volume, intensity, surface) has not been clearly established. From what we do know, menstrual disturbances, caloric restriction, lower bone density, muscle weakness and leg length differences are risk factors for stress fracture. Other time-honoured risk factors such as lower extremity alignment have not been shown to be causative even though anecdotal evidence indicates they are likely to play an important role in stress fracture pathogenesis.

  17. [Predictive factors of anxiety disorders].

    Science.gov (United States)

    Domschke, K

    2014-10-01

    Anxiety disorders are among the most frequent mental disorders in Europe (12-month prevalence 14%) and impose a high socioeconomic burden. The pathogenesis of anxiety disorders is complex with an interaction of biological, environmental and psychosocial factors contributing to the overall disease risk (diathesis-stress model). In this article, risk factors for anxiety disorders will be presented on several levels, e.g. genetic factors, environmental factors, gene-environment interactions, epigenetic mechanisms, neuronal networks ("brain fear circuit"), psychophysiological factors (e.g. startle response and CO2 sensitivity) and dimensional/subclinical phenotypes of anxiety (e.g. anxiety sensitivity and behavioral inhibition), and critically discussed regarding their potential predictive value. The identification of factors predictive of anxiety disorders will possibly allow for effective preventive measures or early treatment interventions, respectively, and reduce the individual patient's suffering as well as the overall socioeconomic burden of anxiety disorders.

  18. Factor of originality in advertising

    OpenAIRE

    Ešner, Rudolf

    2009-01-01

    The bachelor thesis deals with exploitation of original attitudes in advertising. The thesis solves answers, what role plays the factor of originality in advertising, when and why firms use that factor, how creators work with it, how consumers perceive the factor and what other elements it generally contains. The bachelor thesis qualifies relationship of advertising and originality, describes and probes practical situations, when originality in advertising can be used as a serious competitive...

  19. Risk factors in school shootings.

    Science.gov (United States)

    Verlinden, S; Hersen, M; Thomas, J

    2000-01-01

    Nine incidents of multiple-victim homicide in American secondary schools are examined and common risk factors are identified. The literature dealing with individual, family, social, societal, and situational risk factors for youth violence and aggression is reviewed along with existing risk assessment methods. Checklists of risk factors for serious youth violence and school violence are used in reviewing each school shooting case. Commonalties among the cases and implications for psychologists practicing in clinical and school settings are discussed.

  20. First course in factor analysis

    CERN Document Server

    Comrey, Andrew L

    2013-01-01

    The goal of this book is to foster a basic understanding of factor analytic techniques so that readers can use them in their own research and critically evaluate their use by other researchers. Both the underlying theory and correct application are emphasized. The theory is presented through the mathematical basis of the most common factor analytic models and several methods used in factor analysis. On the application side, considerable attention is given to the extraction problem, the rotation problem, and the interpretation of factor analytic results. Hence, readers are given a background of

  1. Summable series and convergence factors

    CERN Document Server

    Moore, Charles N

    1938-01-01

    Fairly early in the development of the theory of summability of divergent series, the concept of convergence factors was recognized as of fundamental importance in the subject. One of the pioneers in this field was C. N. Moore, the author of the book under review.... Moore classifies convergence factors into two types. In type I he places the factors which have only the property that they preserve convergence for a convergent series or produce convergence for a summable series. In type II he places the factors which not only maintain or produce convergence but have the additional property that

  2. Gene regulation by growth factors

    International Nuclear Information System (INIS)

    Metz, R.; Gorham, J.; Siegfried, Z.; Leonard, D.; Gizang-Ginsberg, E.; Thompson, M.A.; Lawe, D.; Kouzarides, T.; Vosatka, R.; MacGregor, D.; Jamal, S.; Greenberg, M.E.; Ziff, E.B.

    1988-01-01

    To coordinate the proliferation and differentiation of diverse cell types, cells of higher eukaryotes communicate through the release of growth factors. These peptides interact with specific transmembrane receptors of other cells and thereby generate intracellular messengers. The many changes in cellular physiology and activity that can be induced by growth factors imply that growth factor-induced signals can reach the nucleus and control gene activity. Moreover, current evidence also suggests that unregulated signaling along such pathways can induce aberrant proliferation and the formation of tumors. This paper reviews investigations of growth factor regulation of gene expression conducted by the authors' laboratory

  3. Factorization method of quadratic template

    Science.gov (United States)

    Kotyrba, Martin

    2017-07-01

    Multiplication of two numbers is a one-way function in mathematics. Any attempt to distribute the outcome to its roots is called factorization. There are many methods such as Fermat's factorization, Dixońs method or quadratic sieve and GNFS, which use sophisticated techniques fast factorization. All the above methods use the same basic formula differing only in its use. This article discusses a newly designed factorization method. Effective implementation of this method in programs is not important, it only represents and clearly defines its properties.

  4. Social networks and factor markets

    DEFF Research Database (Denmark)

    Abay, Kibrom Araya; Kahsay, Goytom Abraha; Berhane, Guush

    In the absence of well-established factor markets, the role of indigenous institutions and social networks can be substantial for mobilizing factors for agricultural production. We investigate the role of an indigenous social network in Ethiopia, the iddir, in facilitating factor market...... transactions among smallholder farmers. Using detailed longitudinal household survey data and employing a difference-in-differences approach, we find that iddir membership improves households’ access to factor markets. Specifically, we find that joining an iddir network improves households’ access to land...

  5. FACTORING- CREDIT OPPORTUNITIES IN ROMANIA

    Directory of Open Access Journals (Sweden)

    ADELA IONESCU

    2013-05-01

    Full Text Available Capital is the main factor of production, business development becomes virtually impossible without taking into account the financial market and the resources it provides to businesses. Any business, regardless of its degree of development, is involving direct contact with financial markets, namely the institutions that mediate mobilization of capital and the services they provide. Understanding the functioning of the financial system, the specific financial mechanisms through which savings are allocated to support capital investments and the costs and risks involved is essential for the development of a solid base for business. In this context, factoring operations can support economic agents, allowing a transfer of commercial receivables from their holder to a factor who commits to their recovery and guarantee such operations even if temporary or permanent insolvency of the debtor . Thus, factoring is a complex technique in at least two aspects, of the debt and the transfer of credit. . Factoring is a means of financing business, especially export-import transactions, less known in Romania. Maybe because of poor business environment popularize the term is as little known as it was a few years ago the leasing. Present in Romanian legislation since 2002, factoring appears as a contract between one party (called adherent, providing goods or service and a banking company or a financial institution specialized (called factor, which the last one shall finance debts pursuing and preservation against credit risks and adherent gives factor by way of sale, debts arising from the sale of goods or services to third parties. The article is divided into three parts. In the first part we defined the concept of factoring and international factoring, then I presented the advantages and development of factoring in Romania, and the last part conclusions.

  6. Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation.

    OpenAIRE

    Rao, L V; Rapaport, S I

    1988-01-01

    Whether the factor VII/tissue factor complex that forms in tissue factor-dependent blood coagulation must be activated to factor VIIa/tissue factor before it can activate its substrates, factor X and factor IX, has been a difficult question to answer because the substrates, once activated, back-activate factor VII. Our earlier studies suggested that human factor VII/tissue factor cannot activate factor IX. Studies have now been extended to the activation of factor X. Reaction mixtures were ma...

  7. Activation of factor VII bound to tissue factor: A key early step in the tissue factor pathway of blood coagulation

    International Nuclear Information System (INIS)

    Rao, L.V.M.; Rapaport, S.I.

    1988-01-01

    Whether the factor VII/tissue factor complex that forms in tissue factor-dependent blood coagulation must be activated to factor VIIa/tissue factor before it can activate its substrates, factor X and IX, has been a difficult question to answer because the substrates, once activated, back-activate factor VII. The earlier studies suggested that human factor VII/tissue factor cannot activate factor IX. Studies have now been extended to the activation of factor X. Reaction mixtures were made with purified factor VII, X, and tissue factor; in some experiments antithrombin III and heparin were added to prevent back-activation of factor VII. Factor X was activated at similar rates in reaction mixtures containing either VII or factor VIIa after an initial 30-sec lag with factor VII. In reaction mixtures with factor VII a linear activation of factor X was established several minutes before cleavage of 125 I-labeled factor VII to the two-chain activated molecule was demonstrable on gel profiles. These data suggest that factor VII/tissue factor cannot activate measurable amounts of factor X over several minutes. Overall, the results support the hypothesis that a rapid preferential activation of factor VII bound to tissue factor by trace amounts of factor Xa is a key early step in tissue factor-dependent blood coagulation

  8. Factors of trade in Europe

    Czech Academy of Sciences Publication Activity Database

    Hanousek, Jan; Kočenda, Evžen

    2014-01-01

    Roč. 38, č. 4 (2014), s. 518-535 ISSN 0939-3625 R&D Projects: GA ČR(CZ) GAP403/12/0080 Grant - others:UK(CZ) UNCE 204005/2012 Institutional support: PRVOUK-P23 Keywords : bilateral trade * factors of trade * panel data Subject RIV: AH - Economics Impact factor: 0.649, year: 2014

  9. Quadratic prediction of factor scores

    NARCIS (Netherlands)

    Wansbeek, T

    1999-01-01

    Factor scores are naturally predicted by means of their conditional expectation given the indicators y. Under normality this expectation is linear in y but in general it is an unknown function of y. II is discussed that under nonnormality factor scores can be more precisely predicted by a quadratic

  10. Hidden Risk Factors for Women

    Science.gov (United States)

    ... A.S.T. Quiz Hidden Stroke Risk Factors for Women Updated:Nov 22,2016 Excerpted from "What Women Need To Know About The Hidden Risk Factors ... 2012) This year, more than 100,000 U.S. women under 65 will have a stroke. Stroke is ...

  11. Factor analysis of multivariate data

    Digital Repository Service at National Institute of Oceanography (India)

    Fernandes, A.A.; Mahadevan, R.

    A brief introduction to factor analysis is presented. A FORTRAN program, which can perform the Q-mode and R-mode factor analysis and the singular value decomposition of a given data matrix is presented in Appendix B. This computer program, uses...

  12. Pineal factors other than melatonin

    NARCIS (Netherlands)

    Ebels, I.

    Some sheep pineal factors other than melatonin are described. A “nonmelatonin” antigonadotropic activity has been detected by application of the inhibition of compensatory ovarian hypertrophy (COH) in unilaterally ovariectomized adult Charles River CD-1 mice. The factor has been extracted from

  13. Stroke Risk Factors and Symptoms

    Science.gov (United States)

    ... » [ pdf, 433 kb ] Order Materials » Stroke Risk Factors and Symptoms Risk Factors for a Stroke Stroke prevention is still ... it. Treatment can delay complications that increase the risk of stroke. Transient ischemic attacks (TIAs). Seek help. ...

  14. Electromagnetic form factors of hadrons

    International Nuclear Information System (INIS)

    Zidell, V.S.

    1976-01-01

    A vector meson dominance model of the electromagnetic form factors of hadrons is developed which is based on the use of unstable particle propagators. Least-square fits are made to the proton, neutron, pion and kaon form factor data in both the space and time-like regions. A good fit to the low-energy nucleon form factor data is obtained using only rho, ω, and phi dominance, and leads to a determination of the vector meson resonance parameters in good agreement with experiment. The nucleon-vector meson coupling constants obey simple sum rules indicating that there exists no hard core contribution to the form factors within theoretical uncertainties. The prediction for the electromagnetic radii of the proton is in reasonable agreement with recent experiments. The pion and kaon charge form factors as deduced from the nucleon form factors assuming vector meson universality are compared to the data. The pion form factor agrees with the data in both the space and time-like regions. The pion charge radius is in agreement with the recent Dubna result, but the isovector P-wave pion-pion phase shift calculated from the theory disagrees with experiment. A possible contribution to the form factors from a heavy rho meson is also evaluated

  15. Shell model and spectroscopic factors

    International Nuclear Information System (INIS)

    Poves, P.

    2007-01-01

    In these lectures, I introduce the notion of spectroscopic factor in the shell model context. A brief review is given of the present status of the large scale applications of the Interacting Shell Model. The spectroscopic factors and the spectroscopic strength are discussed for nuclei in the vicinity of magic closures and for deformed nuclei. (author)

  16. EAMJ Risk Factors 10.indd

    African Journals Online (AJOL)

    2010-02-02

    Feb 2, 2010 ... Several factors have been suggested as independent risk factors for their development. Identification of these ... with age, gender or haematological test. ... A meta-analysis of prospective studies on ..... The marked difference may be because monthly .... and dyslipidemia among patients taking first-line,.

  17. Factors That Shape Design Thinking

    Science.gov (United States)

    Gray, Colin M.

    2013-01-01

    A wide range of design literature discusses the role of the studio and its related pedagogy in the development of design thinking. Scholars in a variety of design disciplines pose a number of factors that potentially affect this development process, but a full understanding of these factors as experienced from a critical pedagogy or student…

  18. Kadison-Kastler stable factors

    DEFF Research Database (Denmark)

    Cameron, Jan; Christensen, Erik; Sinclair, Allan M.

    2014-01-01

    It is proven that a pair of continuous finite von Neumann algebra factors are unitarily equivalent if sufficiently close and one satisfies a certain cohomological condition.......It is proven that a pair of continuous finite von Neumann algebra factors are unitarily equivalent if sufficiently close and one satisfies a certain cohomological condition....

  19. Human factors influencing decision making

    OpenAIRE

    Jacobs, Patricia A.

    1998-01-01

    This report supplies references and comments on literature that identifies human factors influencing decision making, particularly military decision making. The literature has been classified as follows (the classes are not mutually exclusive): features of human information processing; decision making models which are not mathematical models but rather are descriptive; non- personality factors influencing decision making; national characteristics influencing decision makin...

  20. Factoring in Factor VIII With Acute Ischemic Stroke.

    Science.gov (United States)

    Siegler, James E; Samai, Alyana; Albright, Karen C; Boehme, Amelia K; Martin-Schild, Sheryl

    2015-10-01

    There is growing research interest into the etiologies of cryptogenic stroke, in particular as it relates to hypercoagulable states. An elevation in serum levels of the procoagulant factor VIII is recognized as one such culprit of occult cerebral infarctions. It is the objective of the present review to summarize the molecular role of factor VIII in thrombogenesis and its clinical use in the diagnosis and prognosis of acute ischemic stroke. We also discuss the utility of screening for serum factor VIII levels among patients at risk for, or those who have experienced, ischemic stroke. © The Author(s) 2015.

  1. Using Bayes factors for multi-factor, biometric authentication

    Science.gov (United States)

    Giffin, A.; Skufca, J. D.; Lao, P. A.

    2015-01-01

    Multi-factor/multi-modal authentication systems are becoming the de facto industry standard. Traditional methods typically use rates that are point estimates and lack a good measure of uncertainty. Additionally, multiple factors are typically fused together in an ad hoc manner. To be consistent, as well as to establish and make proper use of uncertainties, we use a Bayesian method that will update our estimates and uncertainties as new information presents itself. Our algorithm compares competing classes (such as genuine vs. imposter) using Bayes Factors (BF). The importance of this approach is that we not only accept or reject one model (class), but compare it to others to make a decision. We show using a Receiver Operating Characteristic (ROC) curve that using BF for determining class will always perform at least as well as the traditional combining of factors, such as a voting algorithm. As the uncertainty decreases, the BF result continues to exceed the traditional methods result.

  2. What factors influence mitigative capacity?

    International Nuclear Information System (INIS)

    Winkler, Harald; Baumert, Kevin; Blanchard, Odile; Burch, Sarah; Robinson, John

    2007-01-01

    This article builds on Yohe's seminal piece on mitigative capacity, which elaborates 'determinants' of mitigative capacity, also reflected in the IPCC's third assessment report. We propose a revised definition, where mitigative capacity is a country's ability to reduce anthropogenic greenhouse gas emissions or enhance natural sinks. By 'ability' we mean skills, competencies, fitness, and proficiencies that a country has attained which can contribute to GHG emissions mitigation. A conceptual framework is proposed, linking mitigative capacity to a country's sustainable development path, and grouping the factors influencing mitigative capacity into three main sets: economic factors, institutional ones, and technology. Both quantitative and qualitative analysis of factors is presented, showing how these factors vary across countries. We suggest that it is the interplay between the three economic factors-income, abatement cost and opportunity cost-that shape mitigative capacity. We find that income is an important economic factor influencing mitigative capacity, while abatement cost is important in turning mitigative capacity into actual mitigation. Technology is a critical mitigative capacity, including the ability to absorb existing climate-friendly technologies or to develop innovative ones. Institutional factors that promote mitigative capacity include the effectiveness of government regulation, clear market rules, a skilled work force and public awareness. We briefly investigate such as high abatement cost or lack of political willingness that prevent mitigative capacity from being translated into mitigation

  3. Corrosion effects on friction factors

    International Nuclear Information System (INIS)

    Magleby, H.L.; Shaffer, S.J.

    1996-01-01

    This paper presents the results of NRC-sponsored material specimen tests that were performed to determine if corrosion increases the friction factors of sliding surfaces of motor-operated gate valves, which could require higher forces to close and open safety-related valves when subjected to their design basis differential pressures. Friction tests were performed with uncorroded specimens and specimens subjected to accelerated corrosion. Preliminary tests at ambient conditions showed that corrosion increased the friction factors, indicating the need for additional tests duplicating valve operating parameters at hot conditions. The additional tests showed friction factors of corroded specimens were 0.1 to 0.2 higher than for uncorroded specimens, and that the friction factors of the corroded specimens were not very dependent on contact stress or corrosion film thickness. The measured values of friction factors for the three corrosion films tested (simulating three operating times) were in the range of 0.3 to 0.4. The friction factor for even the shortest simulated operating time was essentially the same as the others, indicating that the friction factors appear to reach a plateau and that the plateau is reached quickly

  4. Conversion factors and oil statistics

    International Nuclear Information System (INIS)

    Karbuz, Sohbet

    2004-01-01

    World oil statistics, in scope and accuracy, are often far from perfect. They can easily lead to misguided conclusions regarding the state of market fundamentals. Without proper attention directed at statistic caveats, the ensuing interpretation of oil market data opens the door to unnecessary volatility, and can distort perception of market fundamentals. Among the numerous caveats associated with the compilation of oil statistics, conversion factors, used to produce aggregated data, play a significant role. Interestingly enough, little attention is paid to conversion factors, i.e. to the relation between different units of measurement for oil. Additionally, the underlying information regarding the choice of a specific factor when trying to produce measurements of aggregated data remains scant. The aim of this paper is to shed some light on the impact of conversion factors for two commonly encountered issues, mass to volume equivalencies (barrels to tonnes) and for broad energy measures encountered in world oil statistics. This paper will seek to demonstrate how inappropriate and misused conversion factors can yield wildly varying results and ultimately distort oil statistics. Examples will show that while discrepancies in commonly used conversion factors may seem trivial, their impact on the assessment of a world oil balance is far from negligible. A unified and harmonised convention for conversion factors is necessary to achieve accurate comparisons and aggregate oil statistics for the benefit of both end-users and policy makers

  5. Factors Influencing of Social Conflict

    Directory of Open Access Journals (Sweden)

    Suwandi Sumartias

    2013-07-01

    Full Text Available Social conflicts that occur in several areas in Indonesia lately, one of them is caused by the weakness of law certainty. This is feared to threaten the integration of the Republic of Indonesia. This study aims to determine the factors that affect social conflict in Manis Lor village in Kuningan district. The method used the explanatory quantitative methods, the statistical test Path Analysis. The study population was a formal and informal community leaders (village chief, clergy, and youth, and the people who involved in a conflict in Manis Lor village Kuningan regency. The result shows a There is no significant influence between social identity factors with social conflict anarchist. b There is significant influence between socio-economic factors with social conflict anarchists. c There is no significant influence between the credibility factor anarchist leaders with social conflict. d There is no significant influence between the motive factor with anarchist social conflict. e There is significant influence between personality factors/beliefs with anarchist social conflict. f There is significant influence of behavioral factors anarchist communication with social conflict.

  6. Factor concentrates for the treatment of factor XIII deficiency.

    Science.gov (United States)

    Gootenberg, J E

    1998-11-01

    Factor XIII deficiency is a severe autosomal recessive bleeding disorder associated with a characteristic pattern of neonatal hemorrhage and a lifelong bleeding diathesis. Even relatively minor trauma can be followed by prolonged and recurrent bleeding. Intracranial hemorrhage is a frequent complication. With the development of safe and effective factor XIII concentrates, reliable prophylactic treatment is possible. Two plasma-derived, virus-inactivated factor XIII concentrates are currently in production. The first, Fibrogammin P, (Centeon LLC, King of Prussia, PA, USA; and Centeon Pharma GmbH, Marburg, Germany) is marketed in Europe, South America, South Africa, and Japan. It is distributed in the United States under a Food and Drug Administration Investigational New Drug Application. A second factor XIII concentrate (Bio Products Laboratory, Elstree, UK) is available for use only on a "named patient" compassionate basis in the United Kingdom. Patients with factor XIII deficiency who receive appropriately timed periodic infusions of such factor XIII concentrates are able to live normal lives, free from catastrophic bleeding episodes.

  7. Sequence Factorization with Multiple References.

    Directory of Open Access Journals (Sweden)

    Sebastian Wandelt

    Full Text Available The success of high-throughput sequencing has lead to an increasing number of projects which sequence large populations of a species. Storage and analysis of sequence data is a key challenge in these projects, because of the sheer size of the datasets. Compression is one simple technology to deal with this challenge. Referential factorization and compression schemes, which store only the differences between input sequence and a reference sequence, gained lots of interest in this field. Highly-similar sequences, e.g., Human genomes, can be compressed with a compression ratio of 1,000:1 and more, up to two orders of magnitude better than with standard compression techniques. Recently, it was shown that the compression against multiple references from the same species can boost the compression ratio up to 4,000:1. However, a detailed analysis of using multiple references is lacking, e.g., for main memory consumption and optimality. In this paper, we describe one key technique for the referential compression against multiple references: The factorization of sequences. Based on the notion of an optimal factorization, we propose optimization heuristics and identify parameter settings which greatly influence 1 the size of the factorization, 2 the time for factorization, and 3 the required amount of main memory. We evaluate a total of 30 setups with a varying number of references on data from three different species. Our results show a wide range of factorization sizes (optimal to an overhead of up to 300%, factorization speed (0.01 MB/s to more than 600 MB/s, and main memory usage (few dozen MB to dozens of GB. Based on our evaluation, we identify the best configurations for common use cases. Our evaluation shows that multi-reference factorization is much better than single-reference factorization.

  8. Cardiovascular risk factors and dementia.

    Science.gov (United States)

    Fillit, Howard; Nash, David T; Rundek, Tatjana; Zuckerman, Andrea

    2008-06-01

    Dementias, such as Alzheimer's disease (AD) and vascular dementia, are disorders of aging populations and represent a significant economic burden. Evidence is accumulating to suggest that cardiovascular disease (CVD) risk factors may be instrumental in the development of dementia. The goal of this review was to discuss the relationship between specific CVD risk factors and dementia and how current treatment strategies for dementia should focus on reducing CVD risks. We conducted a review of the literature for the simultaneous presence of 2 major topics, cardiovascular risk factors and dementia (eg, AD). Special emphasis was placed on clinical outcome studies examining the effects of treatments of pharmacologically modifiable CVD risk factors on dementia and cognitive impairment. Lifestyle risk factors for CVD, such as obesity, lack of exercise, smoking, and certain psychosocial factors, have been associated with an increased risk of cognitive decline and dementia. Some evidence suggests that effectively managing these factors may prevent cognitive decline/dementia. Randomized, placebo-controlled trials of antihypertensive medications have found that such therapy may reduce the risk of cognitive decline, and limited data suggest a benefit for patients with AD. Some small open-label and randomized clinical trials of statins have observed positive effects on cognitive function; larger studies of statins in patients with AD are ongoing. Although more research is needed, current evidence indicates an association between CVD risk factors--such as hypertension, dyslipidemia, and diabetes mellitus--and cognitive decline/dementia. From a clinical perspective, these data further support the rationale for physicians to provide effective management of CVD risk factors and for patients to be compliant with such recommendations to possibly prevent cognitive decline/dementia.

  9. Improved multivariate polynomial factoring algorithm

    International Nuclear Information System (INIS)

    Wang, P.S.

    1978-01-01

    A new algorithm for factoring multivariate polynomials over the integers based on an algorithm by Wang and Rothschild is described. The new algorithm has improved strategies for dealing with the known problems of the original algorithm, namely, the leading coefficient problem, the bad-zero problem and the occurrence of extraneous factors. It has an algorithm for correctly predetermining leading coefficients of the factors. A new and efficient p-adic algorithm named EEZ is described. Bascially it is a linearly convergent variable-by-variable parallel construction. The improved algorithm is generally faster and requires less store then the original algorithm. Machine examples with comparative timing are included

  10. Quality factors for monoenergetic neutrons

    International Nuclear Information System (INIS)

    Cross, W.G.; Ing, H.

    1984-01-01

    Mean quality factors anti Q(E/sub n/), for the dose resulting from first interactons of monoenergetic neutrons in tissue, have been calculated at energies from thermal to 14.7 MeV. Knowledge of these values, along with kerma factors, allows the calculation of the heavy-particle dose equivalent for any known neutron spectrum in tissue. The partial quality factors for the dose delivered by C, N, and O elastic and inelastic recoils are found to be virtually independent of the scattering angular distributions and are given by simple expressions

  11. Nucleocytoplasmic shuttling of transcription factors

    DEFF Research Database (Denmark)

    Cartwright, P; Helin, K

    2000-01-01

    To elicit the transcriptional response following intra- or extracellular stimuli, the signals need to be transmitted to their site of action within the nucleus. The nucleocytoplasmic shuttling of transcription factors is a mechanism mediating this process. The activation and inactivation...... of the transcriptional response is essential for cells to progress through the cell cycle in a normal manner. The involvement of cytoplasmic and nuclear accessory molecules, and the general nuclear membrane transport components, are essential for this process. Although nuclear import and export for different...... transcription factor families are regulated by similar mechanisms, there are several differences that allow for the specific activation of each transcription factor. This review discusses the general import and export pathways found to be common amongst many different transcription factors, and highlights...

  12. Secreted factors as synaptic organizers.

    Science.gov (United States)

    Johnson-Venkatesh, Erin M; Umemori, Hisashi

    2010-07-01

    A critical step in synaptic development is the differentiation of presynaptic and postsynaptic compartments. This complex process is regulated by a variety of secreted factors that serve as synaptic organizers. Specifically, fibroblast growth factors, Wnts, neurotrophic factors and various other intercellular signaling molecules are proposed to regulate presynaptic and/or postsynaptic differentiation. Many of these factors appear to function at both the neuromuscular junction and in the central nervous system, although the specific function of the molecules differs between the two. Here we review secreted molecules that organize the synaptic compartments and discuss how these molecules shape synaptic development, focusing on mammalian in vivo systems. Their critical role in shaping a functional neural circuit is underscored by their possible link to a wide range of neurological and psychiatric disorders both in animal models and by mutations identified in human patients. © The Authors (2010). Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

  13. Disadvantage factor for anisotropic scattering

    International Nuclear Information System (INIS)

    Saad, E.A.; Abdel Krim, M.S.; EL-Dimerdash, A.A.

    1990-01-01

    The invariant embedding method is used to solve the problem for a two region reactor with anisotropic scattering and to compute the disadvantage factor necessary for calculating some reactor parameters

  14. Calculation of pion form factor

    International Nuclear Information System (INIS)

    Vahedi, N.; Amirarjomand, S.

    1975-09-01

    The pion form factor is calculated using the structure function Wsub(2), which incorporates kinematical constraints, threshold behaviour and scaling. The Bloom-Gilman sum rule is used and only the two leading Regge trajectories are taken into account

  15. EAMJ Factors Aug.indd

    African Journals Online (AJOL)

    2009-08-01

    Aug 1, 2009 ... Objective: To bridge the existing gaps by examining the factors associated with attrition. Design: ... Results: In this cohort study, 1353 women were enrolled at delivery and 1188 (88%) ... wage earners with poor social support.

  16. HIV: Social and Environmental Factors

    Centers for Disease Control (CDC) Podcasts

    Dr. Kevin Fenton, Director of CDC’s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, discusses how social and environmental factors may put African Americans at greater risk for HIV.

  17. Lithuanian Population Aging Factors Analysis

    Directory of Open Access Journals (Sweden)

    Agnė Garlauskaitė

    2015-05-01

    Full Text Available The aim of this article is to identify the factors that determine aging of Lithuania’s population and to assess the influence of these factors. The article shows Lithuanian population aging factors analysis, which consists of two main parts: the first describes the aging of the population and its characteristics in theoretical terms. Second part is dedicated to the assessment of trends that influence the aging population and demographic factors and also to analyse the determinants of the aging of the population of Lithuania. After analysis it is concluded in the article that the decline in the birth rate and increase in the number of emigrants compared to immigrants have the greatest impact on aging of the population, so in order to show the aging of the population, a lot of attention should be paid to management of these demographic processes.

  18. Environmental risk factors and pressures

    International Nuclear Information System (INIS)

    Klinda, J.; Lieskovska, Z.

    1998-01-01

    In this chapter the physical risk factors (as radiation [air contamination, contamination of the environment components and food contamination], radon and its radioactive decay products, radioactive wastes, noise), chemical risk factors [chemical substances, xenobiotics in the food chain the ozone depletion], wastes (waste generation, waste management, municipal waste management, import, export and transit of waste) and natural an technological hazards (water quality deterioration as a result of various accidents and fire risk) in the Slovak Republic in 1997 are reviewed

  19. Factorization-algebraization-path integration

    International Nuclear Information System (INIS)

    Inomata, A.; Wilson, R.

    1986-01-01

    The authors review the method of factorization proposed by Schroedinger of a quantum mechanical second-order linear differential equation into a product of two first-order differential operators, often referred to as ladder operators, as well as the modifications made to Schroedinger's method by Infeld and Hull. They then review the group theoretical treatments proposed by Miller of the Schroedinger-Infeld-Hull factorizations and go on to demonstrate the application of dynamical symmetry to path integral calculations. 30 references

  20. Factors determining UK album success

    OpenAIRE

    Elliott, Caroline; Simmons, Robert

    2011-01-01

    This article uses a recently compiled dataset on the UK album sales to determine which factors contribute to best-selling album sales success. We control for factors including length of time since release, nationality of artist, artist type and album type, testing the increasing returns to information hypothesis. Information on general public online review scores for the albums in the dataset allows for a strong test of the accuracy of online reviews in predicting music sales, as online revie...

  1. Virulence Factors of Streptococcus mutans.

    Science.gov (United States)

    1986-08-01

    763512/715242 Final Report U VIRULENCE FACTORS OF STREPTOCOCCUS MUTANS U Samuel Rosen Department of Oral Biology For the Period April 1, 1983 - June 30...00 FINAL REPORT VIRULENCE FACTORS OF STREPTOCOCCUS MUTANS Sam Rosen, Irving Shklair, E. X. Beck and F. M. Beck Ohio State University Columbus,Oh and...206-212. Johnson CP, Gorss S, Hillman JD (1978). Cariogenic properties of LDH deficient mutants of streptococcus mutans . J Dent Res 57, Special Issue

  2. Power peaking nuclear reliability factors

    International Nuclear Information System (INIS)

    Hassan, H.A.; Pegram, J.W.; Mays, C.W.; Romano, J.J.; Woods, J.J.; Warren, H.D.

    1977-11-01

    The Calculational Nuclear Reliability Factor (CNRF) assigned to the limiting power density calculated in reactor design has been determined. The CNRF is presented as a function of the relative power density of the fuel assembly and its radial local. In addition, the Measurement Nuclear Reliability Factor (MNRF) for the measured peak hot pellet power in the core has been evaluated. This MNRF is also presented as a function of the relative power density and radial local within the fuel assembly

  3. FACTORS INFLUENCING SECOND LANGUAGE ACQUISITION

    Directory of Open Access Journals (Sweden)

    Siti Khasinah

    2014-05-01

    Full Text Available Motivation, attitude, age, intelligence, aptitude, cognitive style, and personality are considered as factors that greatly influence someone in the process of his or her second language acquisition. Experts state that those factors give a more dominant contribution in SLA to learners variedly, depend on who the learners are, their age, how they behave toward the language, their cognitive ability, and also the way they learn.

  4. Clinical Application of Wedge Factor

    International Nuclear Information System (INIS)

    Choi, Dong Rak; Ahn, Yong Chan; Huh, Sueng Jae

    1995-01-01

    Purpose : In general. The wedge factors which are used clinical practices are ignored of dependency on field sizes and depths. In this present, we investigated systematically the depth and field size dependency to determine the absorbed dose more accurately. Methods : The wedge factors for each wedge filter were measured at various depth (depth of Dmax, 5cm, 10cm, and 15cm) and field sizes (5 X 5cm, 10 X 10cm, 15 X 15cm, 20 X 20 cm) by using 4-,6-, and 10-MV X rays. By convention, wedge factors are determined by taking the ratio of the central axis ionization readings when the wedge filter is in place to those of the open field in same field size and measurement depth. In this present work, we determined the wedge factors for 4-, 6-, and 10-MV X rays from Clinac 600C and 2100C linear accelerators (manufactured by Varian Associates, Inc., Palo Alto, CA). To confirm that the wedge was centered., measurements were done with the two possible wedge position and various collimator orientations. Results : The standard deviations of measured values are within 0.3% and the depth dependence of wedge factor is greater for the lower energies. Especially, the variation of wedge factor is no less than 5% for 4- and 6- MV X rays with more than 45 .deg. wedge filter. But there seems to be a small dependence on field size. Conclusion : The results of this study show a dependence on the point of measurement. There also seems to be a small dependence on field size. And so, we should consider the depth and field size dependence in determining the wedge factors. If one wedge factor were to be used for each wedge filter, it seems that the measurement for a 10cm X 10cm field size at a depth of 10cm would be a reasonable choice

  5. Demand, Energy, and Power Factor

    Science.gov (United States)

    1994-08-01

    POWER FACTOR DEFINITION I Basically , power factor (pf) is a measure of how effectively the plant uses the electricity it purchases from the utility. It...not be made available by the plant. U 24 This video is relatively short, less than fifteen-minutes, and covers the basics on demand, block extenders... ratemaking methodology and test period as used in determining the NC-RS rates. Pending final decision by the FERC, the Federal Government would pay a rate as

  6. Environmental Factors and Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Omer Faruk Tekbas

    2008-10-01

    Full Text Available Epidemiological and clinical observations have led to the hypothesis that the risk of developing cardiovascular diseases is influenced not only by genetic, lifestyle and major risk factors, but also by environmental factors. Environmental factors are considered key determinants of cardiovascular diseases. Although lifestyle choices such as smoking, diet, and exercise are viewed as major environmental influences, the contribution of pollutants and environmental chemicals is less clear. Accumulating evidence suggests that exposure to physically and chemical pollutants could elevate the risk of cardiovascular diseases. Many epidemiological studies report that exposure to physically, biologically and socio-cultural environmental factors are associated with an increase in cardiovascular mortality. Relationships between environmental factors and coronary arter disease, arhythmias, and cardiomyopathies have been reported. Exposures to arsenic, lead, cadmium, pollutant gases, solvents, and pesticides have also been linked to increased incidence of cardiovascular disease. In this paper, I review that relationships between exposure to physically, chemical, biologically and socio-cultural environmental factors and cardiovascular diseases. [TAF Prev Med Bull 2008; 7(5.000: 435-444

  7. Human factors in resuscitation teaching.

    Science.gov (United States)

    Norris, Elizabeth M; Lockey, Andrew S

    2012-04-01

    There is an increasing interest in human factors within the healthcare environment reflecting the understanding of their impact on safety. The aim of this paper is to explore how human factors might be taught on resuscitation courses, and improve course outcomes in terms of improved mortality and morbidity for patients. The delivery of human factors training is important and this review explores the work that has been delivered already and areas for future research and teaching. Medline was searched using MESH terms Resuscitation as a Major concept and Patient or Leadership as core terms. The abstracts were read and 25 full length articles reviewed. Critical incident reporting has shown four recurring problems: lack of organisation at an arrest, lack of equipment, non functioning equipment, and obstructions preventing good care. Of these, the first relates directly to the concept of human factors. Team dynamics for both team membership and leadership, management of stress, conflict and the role of debriefing are highlighted. Possible strategies for teaching them are discussed. Four strategies for improving human factors training are discussed: team dynamics (including team membership and leadership behaviour), the influence of stress, debriefing, and conflict within teams. This review illustrates how human factor training might be integrated further into life support training without jeopardising the core content and lengthening the courses. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  8. Growth factors and new periodontology

    Directory of Open Access Journals (Sweden)

    Paknejad M

    1999-06-01

    Full Text Available Growth factors are biological mediators that have a key roll in proliferation, chemotaxy and"ndifferentiation by acting on specific receptors on the surface of cells and regulating events in wound"nhealing.They can be considered hormones that are not released in to the blood stream but have one a"nlocal action. Some of these factors can regulate premature change in GO to Gl phase in cell devesion"ncycle and even may stimulate synthesis of DNA in suitable cells, Growth substances, primarily secreted"nby fibroblasts, endothelia! cells, macrophages and platelet, include platelet derived growth factor"n(PDGF, insulin like growth factor (IGF transforming growth factor (TGFa and (3 and bone"nmorphogenetic proteins BMPs that approximately are the most important of them. (BMPs could be"nused to control events during periodontal, craniofacial and implant wound healing through favoring bone"nformation"nAccording toLynch, combination of PGDF and IGF1 would be effective in promoting growth of all the"ncomponents of the periodontium."nThe aim of this study was to characterize growth factor and review the literature to determine the"nmechanism of their function, classification and application in implant and periodontal treatment.

  9. Sexual harassment: identifying risk factors.

    Science.gov (United States)

    O'Hare, E A; O'Donohue, W

    1998-12-01

    A new model of the etiology of sexual harassment, the four-factor model, is presented and compared with several models of sexual harassment including the biological model, the organizational model, the sociocultural model, and the sex role spillover model. A number of risk factors associated with sexually harassing behavior are examined within the framework of the four-factor model of sexual harassment. These include characteristics of the work environment (e.g., sexist attitudes among co-workers, unprofessional work environment, skewed sex ratios in the workplace, knowledge of grievance procedures for sexual harassment incidents) as well as personal characteristics of the subject (e.g., physical attractiveness, job status, sex-role). Subjects were 266 university female faculty, staff, and students who completed the Sexual Experience Questionnaire to assess the experience of sexual harassment and a questionnaire designed to assess the risk factors stated above. Results indicated that the four-factor model is a better predictor of sexual harassment than the alternative models. The risk factors most strongly associated with sexual harassment were an unprofessional environment in the workplace, sexist atmosphere, and lack of knowledge about the organization's formal grievance procedures.

  10. Modifying factors for metabolic parameters

    International Nuclear Information System (INIS)

    Inaba, Jiro

    1990-01-01

    Studies on factors which influence the metabolic parameter for calculation of radiation doses from intakes of radionuclides are very important for estimation of the doses for the general public, because the present procedures recommended by the International Commission on Radiological Protection is for occupationally exposed workers and the underlying metabolic and dosimetric models have been developed from studies on adult man and experiments on adult animals and from observations on radionuclides in physico-chemically simple form. Many factors have been reported to influence the metabolic parameters. Among them, the food-chain involvement of radionuclides and the age-dependence in humans and animals are most significant as environmental and physiological factor, respectively. In connection with the age-dependence of dose calculation, the ICRP started a new programme. They organized a Task Group on Age-Dependent Dose-Factors where relevant information on metabolic and biokinetic parameters are presently being reviewed for development of a set of dose factors for the following age-groups: infant, 1-year-old, 5-year-old, 10-year-old, 15-year-old, and ICRP Reference Man. The first stage of the work is for age-dependent integrated organ and effective dose factors for radioisotopes of the following elements: hydrogen, carbon, iodine, cesium, strontium, plutonium and americium. (author)

  11. Multi-factor authentication using quantum communication

    Science.gov (United States)

    Hughes, Richard John; Peterson, Charles Glen; Thrasher, James T.; Nordholt, Jane E.; Yard, Jon T.; Newell, Raymond Thorson; Somma, Rolando D.

    2018-02-06

    Multi-factor authentication using quantum communication ("QC") includes stages for enrollment and identification. For example, a user enrolls for multi-factor authentication that uses QC with a trusted authority. The trusted authority transmits device factor information associated with a user device (such as a hash function) and user factor information associated with the user (such as an encrypted version of a user password). The user device receives and stores the device factor information and user factor information. For multi-factor authentication that uses QC, the user device retrieves its stored device factor information and user factor information, then transmits the user factor information to the trusted authority, which also retrieves its stored device factor information. The user device and trusted authority use the device factor information and user factor information (more specifically, information such as a user password that is the basis of the user factor information) in multi-factor authentication that uses QC.

  12. Rare coagulation disorders: fibrinogen, factor VII and factor XIII.

    Science.gov (United States)

    de Moerloose, P; Schved, J-F; Nugent, D

    2016-07-01

    Rare coagulation disorders (RCDs) include the inherited deficiencies of fibrinogen, factor (F) II, FV, combined FV and VIII, FVII, FX, combined FVII and X, FXI, FXIII and combined congenital deficiency of vitamin K-dependent factors (VKCFDs). Despite their rarity, a deep comprehension of all these disorders is essential to really understand haemostasis. Indeed, even if they share some common features each RCD has some particularity which makes it unique. In this review, we focus on three disorders: fibrinogen, FVII and FXIII. © 2016 John Wiley & Sons Ltd.

  13. Self-similar factor approximants

    International Nuclear Information System (INIS)

    Gluzman, S.; Yukalov, V.I.; Sornette, D.

    2003-01-01

    The problem of reconstructing functions from their asymptotic expansions in powers of a small variable is addressed by deriving an improved type of approximants. The derivation is based on the self-similar approximation theory, which presents the passage from one approximant to another as the motion realized by a dynamical system with the property of group self-similarity. The derived approximants, because of their form, are called self-similar factor approximants. These complement the obtained earlier self-similar exponential approximants and self-similar root approximants. The specific feature of self-similar factor approximants is that their control functions, providing convergence of the computational algorithm, are completely defined from the accuracy-through-order conditions. These approximants contain the Pade approximants as a particular case, and in some limit they can be reduced to the self-similar exponential approximants previously introduced by two of us. It is proved that the self-similar factor approximants are able to reproduce exactly a wide class of functions, which include a variety of nonalgebraic functions. For other functions, not pertaining to this exactly reproducible class, the factor approximants provide very accurate approximations, whose accuracy surpasses significantly that of the most accurate Pade approximants. This is illustrated by a number of examples showing the generality and accuracy of the factor approximants even when conventional techniques meet serious difficulties

  14. Factors Influencing Healthcare Service Quality

    Directory of Open Access Journals (Sweden)

    Ali Mohammad Mosadeghrad

    2014-07-01

    Full Text Available Background The main purpose of this study was to identify factors that influence healthcare quality in the Iranian context. Methods Exploratory in-depth individual and focus group interviews were conducted with 222 healthcare stakeholders including healthcare providers, managers, policy-makers, and payers to identify factors affecting the quality of healthcare services provided in Iranian healthcare organisations. Results Quality in healthcare is a production of cooperation between the patient and the healthcare provider in a supportive environment. Personal factors of the provider and the patient, and factors pertaining to the healthcare organisation, healthcare system, and the broader environment affect healthcare service quality. Healthcare quality can be improved by supportive visionary leadership, proper planning, education and training, availability of resources, effective management of resources, employees and processes, and collaboration and cooperation among providers. Conclusion This article contributes to healthcare theory and practice by developing a conceptual framework that provides policy-makers and managers a practical understanding of factors that affect healthcare service quality.

  15. TRASYS form factor matrix normalization

    Science.gov (United States)

    Tsuyuki, Glenn T.

    1992-01-01

    A method has been developed for adjusting a TRASYS enclosure form factor matrix to unity. This approach is not limited to closed geometries, and in fact, it is primarily intended for use with open geometries. The purpose of this approach is to prevent optimistic form factors to space. In this method, nodal form factor sums are calculated within 0.05 of unity using TRASYS, although deviations as large as 0.10 may be acceptable, and then, a process is employed to distribute the difference amongst the nodes. A specific example has been analyzed with this method, and a comparison was performed with a standard approach for calculating radiation conductors. In this comparison, hot and cold case temperatures were determined. Exterior nodes exhibited temperature differences as large as 7 C and 3 C for the hot and cold cases, respectively when compared with the standard approach, while interior nodes demonstrated temperature differences from 0 C to 5 C. These results indicate that temperature predictions can be artificially biased if the form factor computation error is lumped into the individual form factors to space.

  16. Peaking-factor of PWR

    International Nuclear Information System (INIS)

    Morioka, Noboru; Kato, Yasuji; Yokoi, M.

    1975-01-01

    Output peaking factor often plays an important role in the safety and operation of nuclear reactors. The meaning of the peaking factor of PWRs is categorized into two features or the peaking factor in core (FQ-core) and the peaking factor on the basis of accident analysis (or FQ-limit). FQ-core is the actual peaking factor realized in nuclear core at the time of normal operation, and FQ-limit should be evaluated from loss of coolant accident and other abnormal conditions. If FQ-core is lower than FQ-limit, the reactor may be operated at full load, but if FQ-core is larger than FQ-limit, reactor output should be controlled lower than FQ-limit. FQ-core has two kinds of values, or the one on the basis of nuclear design, and the other actually measured in reactor operation. The first FQ-core should be named as FQ-core-design and the latter as FQ-core-measured. The numerical evaluation of FQ-core-design is as follows; FQ-core-design of three-dimensions is synthesized with FQ-core horizontal value (X-Y) and FQ-core vertical value, the former one is calculated with ASSY-CORE code, and the latter one with one dimensional diffusion code. For the evaluation of FQ-core-measured, on-site data observation from nuclear reactor instrumentation or off-site data observation is used. (Iwase, T.)

  17. [Risk factors of necrotizing enterocolitis].

    Science.gov (United States)

    Tapia-Rombo, C A; Velasco-Lavín, M R; Nieto-Caldelas, A

    1993-09-01

    The purpose of the present study is to compare risk factors of necrotizing enterocolitis (NEC) between two group: group A, newborns with the disease and group B, newborns with other diseases different from NEC, in order to know if these risk factors are more frequent or not in the first group. We assessed the clinical records of all the patients hospitalized in the Neonatal Intensive Care Unit and Neonatology Service of the La Raza General Hospital between 1987 and 1991 with the diagnosis of NEC. They were compared with 65 clinical records chosen at random of patients hospitalized in the same Unit with other diagnosis at the same time, and who were discharged by improvement or deceased. In all of them were look for known risk factors for NEC generally accepted such as: prematurity, neonatal asphyxia, poliglobulia, cyanotic congenital heart disease, patent ductus arteriosus, respiratory distress syndrome, catheterization of umbilical vessels, early feeding of elevated formula increases, exchange exchange transfusion, hypoxic ischemic encephalopathy, infection, etc. Just 25 records of the possible 50 with the diagnosis of NEC full filled inclusion criteria. There were no statistically significant difference in weight, sex, mortality and known risk factors of NEC between both groups. Were concluded that NEC is a disease of unknown etiology that should be studied more thoroughly. The known risk factors must be avoided because the patient susceptibility probably play an important role.

  18. Epistaxis: Prevailing Factors and Treatment

    Directory of Open Access Journals (Sweden)

    Secchi, Myrian Marajó Dal

    2009-12-01

    Full Text Available Introduction: The epistaxis is one the most frequent otorhinolaryngologic emergencies in the medical practice. It is a benign affection, but the refractory cases require hospital admission. Objective: To evaluate prevailing factors in patients with epistaxis and treatment. Form of study: Retrospective study. Method: 60 patients with diagnosis of epistaxis were evaluated and they needed hospital admission between 2005 and 2006. Results: The main prevailing factors were: Systemic arterial hypertension 36% (n= 22, trauma 16% (n=10 and coagulopathy 5% (n=3. The treatment was the use of nasal splint: anterior 58% (n=35 and antero-posterior 27% (n=16, the electrocauterization of the identified bloody point 7% (n=4, endoscopic arterial bandage 8% (n=5 in severe epistaxis. For the patients with antero-posterior splint with recurrence of bleeding in the first 24 hours (five patients, after clinical stabilization, an arterial bandage was indicated by endoscopic means; four patients had systemic arterial hypertension and in one patient no prevailing factor was identified. Conclusion: The main associated prevailing factors were systemic arterial hypertension, trauma and coagulopathy. The treatment depends on the type, severity and cause of bleeding, initially the anterior and antero-posterior splint for bleeding control. The early endoscopic arterial bandage is indicated in patients with severe epistaxis and prevailing factors, and prolonged admission and morbidities associated with nasal splint should be avoided.

  19. Security Gaps In Authentication Factor Credentials

    Directory of Open Access Journals (Sweden)

    Neeraj A. Sharma

    2015-08-01

    Full Text Available Authentication factors refer to user login credentials that a user supplies to an authentication process for it to decide whether to grant or deny access. While two-factor and three-factor authentication generally provides better security than one-factor authentication the aim of this paper is to review security in individual authentication factor credentials that are in use nowadays. These credentials will be discussed in factor categories knowledge factor possession factor and inherence factor. The paper details current security gaps and some novel approaches to diminish the gaps in these authentication factors. We believe that our recommendations will inspire development of better authentication credentials and systems.

  20. Success factors in technology development

    Science.gov (United States)

    Preston, John T.

    1995-01-01

    Universities in the U.S. have a significant impact on business through the transfer of technology. This paper describes goals and philosophy of the Technology Licensing Office at the Massachusetts Institute of Technology. This paper also relates the critical factors for susscessful technology transfer, particularly relating to new business formation. These critical factors include the quality of the technology, the quality of the management, the quality of the investor, the passion for success, and the image of the company. Descriptions of three different levels of investment are also given and the most successful level of investment for starting a new company is reviewed. Licensing to large companies is also briefly reviewed, as this type of licensing requires some different strategies than that of licensing to start-up companies. High quality critical factors and intelligent investment create rewards for the parties and successful ventures.

  1. Critical factors for EIA implementation

    DEFF Research Database (Denmark)

    Zhang, Jasmine; Kørnøv, Lone; Christensen, Per

    2013-01-01

    After decades of development, the gap between expectations of Environment Impact Assessments (EIA) and their practical performance remains significant. Research has been done to identify the critical factors for an effective implementation of EIA. However, this research, to a large extent, has...... not been cumulated and analysed comprehensively according to the stages of the EIA process. This paper contributes to the critical review of the literature on EIA implementation and effectiveness by cumulating mainly empirical findings in an implementation theoretical perspective. It focuses on the links...... between different critical factors and how they relate to different stages in the EIA and thus influence the decision making process. After reviewing 33 refereed journal articles published between 1999 and 2011, we identified 203 notions of critical factors. Of these, 102 related to different stages...

  2. Factors Driving Business Intelligence Culture

    Directory of Open Access Journals (Sweden)

    Rimvydas Skyrius

    2016-05-01

    Full Text Available The field of business intelligence (BI, despite rapid technology advances, continues to feature inadequate levels of adoption. The attention of researchers is shifting towards hu-man factors of BI adoption. The wide set of human factors influencing BI adoption con-tains elements of what we call BI culture – an overarching concept covering key managerial issues that come up in BI implementation. Research sources provide different sets of features pertaining to BI culture or related concepts – decision-making culture, analytical culture and others. The goal of this paper is to perform the review of research and practical sources to examine driving forces of BI – data-driven approaches, BI agility, maturity and acceptance – to point out culture-related issues that support BI adoption and to suggest an emerging set of factors influencing BI culture.

  3. Factors controlling metal fuel lifetime

    International Nuclear Information System (INIS)

    Porter, D.L.; Hofman, G.L.; Seidel, B.R.; Walters, L.C.

    1986-01-01

    The reliability of metal fuel elements is determined by a fuel burnup at which a statistically predicted number of fuel breaches would occur, the number of breaches determined by the amount of free fission gas which a particular reactor design can tolerate. The reliability is therefore measured using experimentally determined breach statistics, or by modelling fuel element behavior and those factors which contribute to cladding breach. The factors are fuel/cladding mechanical and chemical interactions, fission gas pressure, fuel phase transformations involving volume changes, and fission product effects on cladding integrity. Experimental data for EBR-II fuel elements has shown that the primary, and perhaps the only significant factor affecting metal fuel reliability, is the pressure-induced stresses caused by fission gas release. Other metal fuel/cladding systems may perform similarly

  4. Perinatal risk factors including malformation

    International Nuclear Information System (INIS)

    Brachner, A.; Grosche, B.

    1991-10-01

    The study gives a survey of the factors most frequently mentioned in the literature as factors likely to adversely affect a pregnancy. One essential aspect is the discussion of those factors that can be counted among the causes of malformations, as among others, prenatal radiation exposure. The study prepared within the framework of the research project 'Radiobiological environmental monitoring in Bavaria' is intended to serve as a basis for a retrospective and prospective evaluation of infant mortality, perinatal conditions and occurrence of malformations in Bavaria, with the principal idea of drawing up an environment - related health survey. The study therefore, in addition to ionizing radiation also takes into account other detectable risks within the ecologic context, as e.g. industrial installations, refuse incineration plants or waste dumps, or urbanity. (orig./MG) [de

  5. Self-government’s factoring

    Directory of Open Access Journals (Sweden)

    Maciej Tokarski

    2011-12-01

    Full Text Available Local self-governments are reliable business partners. Such belief, confirmed by long-term experience, results in eager collaboration between financial institutions and these entities. Contrary to its name, local self-governments do not constitute the main beneficiaries of the self-government’s factoring. The enterprises which perform investments commissioned by a local commune, district or province are the principal recipients. Such firms may utilise it independently if they have signed contracts with the proper authority and conduct sale with deferred payment, or they may be forced to utilise factoring when they submit their bids in self-government’s tenders within which a refinance guarantee is required. The main aim of the article is to present the mechanism and features of the self-government’s factoring, as well as the benefits which the entities involved enjoy.

  6. Organizational Factors and Intrapreneurial Competences

    Directory of Open Access Journals (Sweden)

    Suzete Antonieta Lizote

    2013-12-01

    Full Text Available This study analyzes the relationship between organizational factors and entrepreneurial competencies of coordinators of undergraduate courses in two community universities in Santa Catarina, Brazil. The organizational factors studied were: management support, freedom at work, rewards, and time available and organizational limitations. Eight entrepreneurial competencies were considered; five included in an achievement set, and three in a planning set. The method was quantitative and descriptive, adopting a structured questionnaire as the data collection tool. Factor analysis, canonical analysis, and multiple regression analysis were performed. The results revealed a positive relationship between the constructs. The most relevant competencies were organizational limitations or uncertainty about tasks, and freedom at work, which indicates the importance having clarity about rules and decisions that should exist both at the level of performance expected of the coordinator, and the freedom that they must feel in their work.

  7. Prognostic factors in Acanthamoeba keratitis.

    Science.gov (United States)

    Kaiserman, Igor; Bahar, Irit; McAllum, Penny; Srinivasan, Sathish; Elbaz, Uri; Slomovic, Allan R; Rootman, David S

    2012-06-01

    To assess the prognostic factors influencing visual prognosis and length of treatment after acanthamoeba keratitis (AK). Forty-two AK eyes of 41 patients treated between 1999 and 2006 were included. A diagnosis of AK was made on the basis of culture results with a corresponding clinical presentation. We calculated the prognostic effect of the various factors on final visual acuity and the length of treatment. Multivariate regression analysis was used to adjust for the simultaneous effects of the various prognostic factors. Mean follow-up was 19.7 ± 21.0 months. Sixty-four percent of cases had > 1 identified risk factor for AK, the most common risk factor being contact lens wear (92.9% of eyes). At presentation, median best spectacle corrected visual acuity (BCVA) was 20/200 (20/30 to Hand Motion [HM]) that improved after treatment to 20/50 (20/20 to Counting Fingers [CF]). Infection acquired by swimming or related to contact lenses had significantly better final BCVA (p = 0.03 and p = 0.007, respectively). Neuritis and pseudodendrites were also associated with better final BCVA (p = 0.04 and p = 0.05, respectively). Having had an epithelial defect on presentation and having been treated with topical steroid were associated with worse final best spectacle corrected visual acuity (BSCVA) (p = 0.0006 and p = 0.04). Multivariate regression analysis found a good initial visual acuity (p = 0.002), infections related to swimming (p = 0.01), the absence of an epithelial defect (p = 0.03), having been treated with chlorhexidine (p = 0.05), and not having receive steroids (p = 0.003) to significantly forecast a good final BCVA. We identified several prognostic factors that can help clinicians evaluate the expected visual damage of the AK infection and thus tailor treatment accordingly. Copyright © 2012 Canadian Ophthalmological Society. All rights reserved.

  8. The selection of occupancy factors

    International Nuclear Information System (INIS)

    Lakey, J.R.A.

    1977-01-01

    An estimate of the proportion of time that an area is occupied by radiation workers is often used in radiological protection to permit relaxation of exposure rate limits above those for continuous occupation. This proportion is known as an occupancy factor and is used most frequently in X-ray facilities. The strategy for controlling the external exposure of radiation workers must be decided before occupancy factors are selected for the design of the radiation protection facilities. When shielding has to be designed the occupancy factor effects the design objectives and permits increased exposure rates at the shield surface. It is useful to note that the selection of occupancy factors with due regard to the expected spatial variation of the exposure rate can help to reduce the range of the worker's radiation exposure because field gradients are usually steeper close to the shield. When other hazards, such as internal exposure, and other constraints, such as cost of the space consumed, are added, the selection of the optimum set of occupancy factors is more difficult. Two zone occupancy factors are discussed in this paper and proposals are made for a strategy to be used when there is more than one hazard and the designer has to meet constraints imposed by limitations of the facilities available. An important feature of the strategy is the avoidance of high radiation exposure to small groups of workers. The errors involved in assessment of the actual dose received by the radiation worker must be taken into account and in particular the selection of the higher exposure rate limits must be made with attention to the accident potential

  9. Theoretical difference between impact factor and influence factor

    Directory of Open Access Journals (Sweden)

    Đilda Pečarić

    2010-06-01

    Full Text Available Bibliometric constructions of "knowledge maps" and "cognitive structures of science" do not differentiate between impact and influence factors. The difference can be constructedaccording to different meaning and interpretation of the terms reference and citation. Reference is "acknowledgment which one author gives to another", whereas citation is "acknowledgment which one document receives from another". Development of Information Science according to period and subject area is analyzed on the corpus of citation literature retrieved from doctoral dissertations in Information Science from 1978 to 2007 at Croatian universities. The research aim is to indicate the difference between document impact factor and author's influence factor (i.e. reference ability to produce effects on actions, behavior, and opinions of authors of doctoral theses. The influence factor serves to distinguish the key role of cited authors in time and according to the duration of the influence (the average age for cited papers of dominant authors in different periods is between eight and ten years. The difference between linear and interactive communication seems vital for the interpretation of cited half-life, i.e. the attitude of one science community towards used information resources and cognitive heritage. The analyzed corpus of 22,210 citations can be divided into three communication phases according to influence factor criteria: in the phase of dialogue and interactive communication 25% of bibliographic units are cited in the first four years; in the second phase another 25% of units are cited from the fifth to the ninth year; after ten years, in the dominant linear communication phase, approximately 30% of units are cited.

  10. Absorption factor for cylindrical samples

    International Nuclear Information System (INIS)

    Sears, V.F.

    1984-01-01

    The absorption factor for the scattering of X-rays or neutrons in cylindrical samples is calculated by numerical integration for the case in which the absorption coefficients of the incident and scattered beams are not equal. An extensive table of values having an absolute accuracy of 10 -4 is given in a companion report [Sears (1983). Atomic Energy of Canada Limited, Report No. AECL-8176]. In the present paper an asymptotic expression is derived for the absorption factor which can be used with an error of less than 10 -3 for most cases of interest in both neutron inelastic scattering and neutron diffraction in crystals. (Auth.)

  11. General introduction and recovery factors

    Science.gov (United States)

    Verma, Mahendra K.

    2017-07-17

    IntroductionThe U.S. Geological Survey (USGS) compared methods for estimating an incremental recovery factor (RF) for the carbon dioxide enhanced oil recovery (CO2-EOR) process involving the injection of CO2 into oil reservoirs. This chapter first provides some basic information on the RF, including its dependence on various reservoir and operational parameters, and then discusses the three development phases of oil recovery—primary, second­ary, and tertiary (EOR). It ends with a brief discussion of the three approaches for estimating recovery factors, which are detailed in subsequent chapters.

  12. Cardiovascular risk factors in men

    DEFF Research Database (Denmark)

    Gyllenborg, J; Rasmussen, S L; Borch-Johnsen, Knut

    2001-01-01

    Males have higher risk of cardiovascular disease (CVD) than premenopausal females. Gonadal steroids are probably involved in the gender difference in CVD, but previous results have been conflicting. We investigated the associations between CVD risk factors and sex hormones in a cross-sectional de......Males have higher risk of cardiovascular disease (CVD) than premenopausal females. Gonadal steroids are probably involved in the gender difference in CVD, but previous results have been conflicting. We investigated the associations between CVD risk factors and sex hormones in a cross...

  13. Efficiency factors in Mie scattering

    International Nuclear Information System (INIS)

    Nussenzveig, H.M.

    1980-04-01

    Asymptotic approximation to the Mie efficiency factors for extinction, absorption and radiation pressure, derived from complex angular momentum theory and averaged over Δβ approximately π (β = size parameter), are given and compared with the exact results. For complex refractive indices N = n + i kappa with 1.1 -2 - 10 -3 % between β = 10 and β = 1000, and computing time is reduced by a factor of order β, so that the Mie formulae can advantageously by replaced by the asymptotic ones in most applications. (Author) [pt

  14. Output factors and scatter ratios

    Energy Technology Data Exchange (ETDEWEB)

    Shrivastava, P N; Summers, R E; Samulski, T V; Baird, L C [Allegheny General Hospital, Pittsburgh, PA (USA); Ahuja, A S; Dubuque, G L; Hendee, W R; Chhabra, A S

    1979-07-01

    Reference is made to a previous publication on output factors and scatter ratios for radiotherapy units in which it was suggested that the output factor should be included in the definitions of scatter-air ratio and tissue-maximum ratio. In the present correspondence from other authors and from the authors of the previous publication, the original definitions and the proposed changes are discussed. Radiation scatter from source and collimator degradation of beam energy and calculation of dose in tissue are considered in relation to the objective of accurate dosimetry.

  15. Effectiveness of human factors simulator

    International Nuclear Information System (INIS)

    Moragas, F.

    2015-01-01

    En 2011, ANAV started the exploitation of the Human Factors Simulator installed in TECNATOM Training Center located in L'Hospital de L'Infant Tarragona. AVAN's Strategic Plan includes the Action Plan for the improvement of human behavior. The plan includes improving the efficiency of the efficiency of the human factors simulator. It is proposed to improve the efficiency into two different terms: winning effectiveness in modeling behaviors, and interweaving the activities in the simulator with the actual strategy of promoting Safety culture and human behaviour. (Author)

  16. The gamma contamination food factor

    International Nuclear Information System (INIS)

    Kukoc, A.H.; Anicin, I.V.; Adzic, P.R.

    1992-01-01

    We suggest that radioactive food contamination, as determined solely by a quantitative gamma-ray spectroscopic measurement, may, apart from the total activity per unit mass, be for quick reference conveniently characterized by another single figure which we call the ''Gamma Contamination Food Factor'' (GCFF). This factor may be defined as the ratio of the total specific activity of gamma-ray-emitting radionuclides in the food sample (except that of 40 K) to the specific activity of 40 K either in the sample itself or in an ''average man''. We discuss briefly the meaning and advantages of these definitions. (author)

  17. Age factors in biometric processing

    CERN Document Server

    Fairhurst, Michael

    2013-01-01

    As biometrics-based identification and identity authentication become increasingly widespread in their deployment, it becomes correspondingly important to consider more carefully issues relating to reliability, usability and inclusion. One factor which is particularly important in this context is that of the relationship between the nature of the measurements extracted from a particular biometric modality and the age of the sample donor, and the effect which age has on physiological and behavioural characteristics invoked in a biometric transaction. In Age Factors in Biometric Processing an in

  18. Social networks and factor markets

    DEFF Research Database (Denmark)

    Abay, Kibrom Araya; Kahsay, Goytom Abraha; Berhane, Guush

    2018-01-01

    We investigate the role of an indigenous social network in Ethiopia, the iddir, in facilitating factor market transactions among smallholder farmers. We use a detailed longitudinal household survey data and employ a fixed effects estimation to identify the effect of iddir membership on factor...... market transactions among farmers. We find that joining an iddir network improves households’ access to land, labour and credit transactions. Our findings also hint that iddir networks may crowd-out borrowing from local moneylenders (locally referred as ‘Arata Abedari’), a relatively expensive credit...

  19. Risk factor for febrile seizures

    Directory of Open Access Journals (Sweden)

    Odalović Dragica

    2014-01-01

    Full Text Available Febrile seizures are the most frequent neurological disorder in the childhood. According to American Academy of Pediatrics (AAP, they have been defined as seizures provoked by high temperature in children aged between 6 months and 5 years, without previous history of afebrile seizures, intracranial infections and other possible causes of seizures. Seizures can be typical and atypical, according to the characteristics. Pathogenesis of this disorder has not been clarified yet, and it is believed to be a combination of genetic factors, high body temperature and brain maturation. The risk factors for recurrence of febrile seizures are: age in which seizures appeared for the first time, epilepsy in the first degree relative, febrile seizures in the first degree relative, frequent diseases with fever and low body temperature on the beginning of seizures. The frequency of recurrent seizures The risk for occurrence of epilepsy in children with simple seizures is about 1-1.5%, which is slightly higher compared to general population, while it increases to 4-15% in patients with complex seizures. However, there is no evidence that therapy prevents occurrence of epilepsy. When the prevention of recurrent seizures is considered, it is necessary to separate simple from complex seizures. The aim of this paper was to analyze the most important risk factors for febrile seizures, and to evaluate their impact on occurrence of recurrent seizures. Our study included 125 children with febrile seizures, aged from 6 months to 5 years. The presence of febrile seizures and epilepsy in the first degree relative has been noted in 22% of children. Typical febrile seizures were observed in 76% of cases, and atypical in 24%. Most patients had only one seizure (73.6%. Children, who had seizure earlier in life, had more frequent recurrences. Both risk factors were present in 25% of patients, while 68% of patients had only one risk factor. For the children with febrile disease

  20. Factores de risco em implantologia

    OpenAIRE

    Sousa, Inês Silveira e Luz Nunes de

    2015-01-01

    A Implantologia tem ganho popularidade na medicina dentária pelos resultados previsíveis em reabilitações de áreas edêntulas, permitindo minimizar as consequências funcionais, fonéticas e estéticas que advém da perda de dentes através de uma solução fixa que satizfaz os pacientes. Esta é uma revisão da literatura existente sobre factores de risco, fracassos e complicações inerentes ao tratamento com implantes dentários. Categorizam-se os factores de risco em implantologia co...