WorldWideScience

Sample records for factor demand linkages

  1. Optimal Monetary Policy with Durable Consumption Goods and Factor Demand Linkages

    DEFF Research Database (Denmark)

    Petrella, Ivan; Santoro, Emiliano

    This paper deals with the implications of factor demand linkages for monetary policy design. We develop a dynamic general equilibrium model with two sectors that produce durable and non-durable goods, respectively. Part of the output produced in each sector is used as an intermediate input......-durable spending in response to a monetary policy shock. A main result of our monetary policy analysis is that strategic complementarities generated by factor demand linkages amplify social welfare loss. As the degree of interconnection between sectors increases, the cost of misperceiving the correct production...

  2. Optimal Monetary Policy with Durable Consumption Goods and Factor Demand Linkages

    DEFF Research Database (Denmark)

    Petrella, Ivan; Santoro, Emiliano

    This paper deals with the implications of factor demand linkages for monetary policy design. We develop a dynamic general equilibrium model with two sectors that produce durable and non-durable goods, respectively. Part of the output produced in each sector is used as an intermediate input of pro...... is crucial, as this does not only influence the user cost of durables through the conventional demand channel, but also affects in opposite directions the real marginal cost of production in either sector through the intermediate input channel.......This paper deals with the implications of factor demand linkages for monetary policy design. We develop a dynamic general equilibrium model with two sectors that produce durable and non-durable goods, respectively. Part of the output produced in each sector is used as an intermediate input......-durable spending in response to a monetary policy shock. A main result of our monetary policy analysis is that strategic complementarities generated by factor demand linkages amplify social welfare loss. As the degree of interconnection between sectors increases, the cost of misperceiving the correct production...

  3. Demand, Energy, and Power Factor

    Science.gov (United States)

    1994-08-01

    demand, but first, let’s talk some more about why electrical demand charges occur. Electric Load Leveling: 5 ** show flip chart of daily utility load (see...and cost savings for energy are available as a result of lowering demand. 3 ’~ show flip chart of block structure (see copy at end of script) Shown... flip chart (see copy at end of script) This is a graphical representation of real, apparent and reactive power in3 an AC circuit. Real power is the power

  4. Sequentiality versus simultaneity: Interrelated factor demand

    NARCIS (Netherlands)

    Asphjell, M.K.; Letterie, W.A.; Nilsen, O.A.; Pfann, G.A.

    2014-01-01

    Firms may adjust capital and labor sequentially or simultaneously. In this paper, we develop a structural model of interrelated factor demand subject to nonconvex adjustment costs and estimated by simulated method of moments. Based on Norwegian manufacturing industry plant-level data, parameter

  5. Sequentiality versus simultaneity: Interrelated factor demand

    NARCIS (Netherlands)

    Asphjell, M.K.; Letterie, W.A.; Nilsen, O.A.; Pfann, G.A.

    2014-01-01

    Firms may adjust capital and labor sequentially or simultaneously. In this paper, we develop a structural model of interrelated factor demand subject to nonconvex adjustment costs and estimated by simulated method of moments. Based on Norwegian manufacturing industry plant-level data, parameter esti

  6. Linkages, contagion and resilience: an input-output scope from the demand and supply side

    OpenAIRE

    García Muñiz, Ana Salomé; Ramos Carvajal, Carmen

    2012-01-01

    The use of linkages to compare productive structures and discover key sectors is an active focus of research in input-output field. In this paper, an extension of the called multilevel indicators (García et al., 2008) to the key sector determination is proposed. The multilevel indicators not only describe industries with a strong influence on the expansion of other sectors in an economy but the immediacy and the transmission capacity of their impacts. The proposal opens a new inquiry about ho...

  7. What factors are driving increasing demand for community nursing?

    Science.gov (United States)

    Chalk, Daniel; Legg, Alison

    2017-01-02

    Demand for district nursing services is increasing significantly. With increasing economic pressures, services are struggling to meet increases in demand, and are looking to become more proactive in planning for future demand. Traditional quantitative forecasting methods have limited use, because of the complexity of inter-linking factors that potentially drive demand for community services. Qualitative system dynamics approaches can be useful to model the complex interplay of causal factors leading to an effect, such as increased demand for services, and identify particular areas of concern for future focus. We ran a facilitated qualitative system dynamics workshop with representatives working across community nursing services in Cornwall. The generated models identified 7 key areas of concern that could be significantly contributing to demand for district nursing services. We outline the identified problem areas in this paper, and discuss potential recommendations to reduce their effects based on causal links identified in the models.

  8. Linkage between passenger demand and surrounding land-use patterns at urban rail transit stations: A canonical correlation analysis method and case study in Chongqing

    Directory of Open Access Journals (Sweden)

    Xin Li

    2016-08-01

    Full Text Available This paper employs a canonical correlation analysis method to quantify the linkage between urban rail transit station demand and the surrounding land-use patterns. It is used to identify key land use variables by evaluating their degrees of contribution to the rail transit station demand. A full month of IC card data and detailed regulatory land use plan from Chongqing, China are collected for model development and validation. The proposed model contributes to offering the capability of targeting key land use patterns and associating them with rail transit station boarding and alighting demand simultaneously. The proposed model can reveal underlying rules between rail transit station demand and land use variables and can be used to evaluate the Transit Oriented Development (TOD plans to improve land use and transit operational efficiency.

  9. Neonatal Risk Factors for Treatment-Demanding Retinopathy of Prematurity

    DEFF Research Database (Denmark)

    Slidsborg, Carina; Jensen, Aksel; Forman, Julie Lyng;

    2016-01-01

    ventilation were the only new statistically independent risk factors to predict the development of treatment-demanding ROP. Modification in the neonatal treatment with mechanical ventilation or blood transfusion did not cause the observed increase in the incidence of preterm infants with treatment...

  10. Latent factor structure of a behavioral economic marijuana demand curve.

    Science.gov (United States)

    Aston, Elizabeth R; Farris, Samantha G; MacKillop, James; Metrik, Jane

    2017-08-01

    Drug demand, or relative value, can be assessed via analysis of behavioral economic purchase task performance. Five demand indices are typically obtained from drug purchase tasks. The goal of this research was to determine whether metrics of marijuana reinforcement from a marijuana purchase task (MPT) exhibit a latent factor structure that efficiently characterizes marijuana demand. Participants were regular marijuana users (n = 99; 37.4% female, 71.5% marijuana use days [5 days/week], 15.2% cannabis dependent) who completed study assessments, including the MPT, during a baseline session. Principal component analysis was used to examine the latent structure underlying MPT indices. Concurrent validity was assessed via examination of relationships between latent factors and marijuana use, past quit attempts, and marijuana expectancies. A two-factor solution was confirmed as the best fitting structure, accounting for 88.5% of the overall variance. Factor 1 (65.8% variance) reflected "Persistence," indicating sensitivity to escalating marijuana price, which comprised four MPT indices (elasticity, O max, P max, and breakpoint). Factor 2 (22.7% variance) reflected "Amplitude," indicating the amount consumed at unrestricted price (intensity). Persistence factor scores were associated with fewer past marijuana quit attempts and lower expectancies of negative use outcomes. Amplitude factor scores were associated with more frequent use, dependence symptoms, craving severity, and positive marijuana outcome expectancies. Consistent with research on alcohol and cigarette purchase tasks, the MPT can be characterized with a latent two-factor structure. Thus, demand for marijuana appears to encompass distinct dimensions of price sensitivity and volumetric consumption, with differential relations to other aspects of marijuana motivation.

  11. DOWRY DEMAND AND HARASSMENT: PREVALENCE AND RISK FACTORS IN INDIA.

    Science.gov (United States)

    Jeyaseelan, Visalakshi; Kumar, Shuba; Jeyaseelan, L; Shankar, Viswanathan; Yadav, Bijesh Kumar; Bangdiwala, Shrikant I

    2015-11-01

    The practice of dowry is widespread in India and refers to the payment of cash/gifts by the bride's family to the bridegroom's family before marriage. Though prohibited by law, dowry is widely practised, and often contributes to severe injuries and even death of young brides. This study examined the prevalence and risk factors for dowry demand and dowry harassment and its psychosocial correlates across different social strata in India, and also by husband and mother-in-law characteristics. In a cross-sectional survey of 9938 women in rural, urban and urban non-slum sites across India conducted in 1998-99, dowry demand was found to be significantly higher (pdowry, this being higher in rural areas (21%) than in urban slum and non-slum areas (about 14% in both). The overall prevalence of dowry harassment among this group of women was 13.3%. Mothers-in-law who had themselves experienced dowry demand were 14 (95% CI 5.0-40.4) and 5 (95% CI 1.3-18.9) times more likely to demand and harass daughters-in-law over dowry, respectively. Another significant risk factor for dowry-related harassment was mother-in law's status in the family. Interventions related to modifiable risk factors, such as increased social support at the community level, should help reduce dowry harassment.

  12. The demand for children as a factor in fertility trends.

    Science.gov (United States)

    Lee, A C

    1989-01-01

    Research studies conducted in the Philippines in 1987 indicate that various factors influence family size preferences and decisions. For instance, surveys found that child mortality, child sex preferences, and parental desire for security in old-age were positively correlated with fertility. On the other hand, maternal education, and the desire for financial and occupational status were inversely related to fertility. As the demand for children is a major determinant in fertility trends, it is important to understand the factors involved in the demand for children. Many of these factors can be subject to policy management, namely, improved education, health, nutrition, and greater participation of women in the labor force. Smaller families may become more desirable if favorable political, economic, and social climates are instituted.

  13. FACTORS AFFECTING DEMAND FOR INTERNET ACCESS IN SAUDI ARABIA

    Directory of Open Access Journals (Sweden)

    Hisham Jameel Bardesi

    2016-07-01

    Full Text Available As internet use in Saudi Arabia are dramatically increasing, a powerful demand is being laid down on internet service purpose where this paper aims at identifying major factors that influence these demand pertaining to internet services. Within a selected theoretical model, such multiple factors are being conceptualized and interrelated. Using time series data, the Ordinary Least Square (OLS technique is employed to analyze the relationships. The results of the model indicated clearly that using the internet in Saudi Arabia is influenced most strongly by the number of educated people, the number of mobile subscribers, income, the number of fixed lines, and employment level. The results also suggest that demographic factors have a significant impact on the demand for internet, specifically, the number of educated people and levels of employment. This paper concludes with a recommendation on increasing the level of understanding of those the factors affecting practitioners who plan and promote new forms of internet services in the current competitive market.

  14. Demand Side Management in Pellet Production: Internal and External Factors

    Science.gov (United States)

    Vigants, Haralds; Blumberga, Dagnija; Veidenbergs, Ivars

    2014-12-01

    This paper demonstrates a demand side management case study: how to save energy and how research and data analysis help to create an energy management system in a pellet production facility; and shows ways to implement the EU energy efficiency directive in production facilities. The study carried out in this research serves as a far-reaching step that can be taken to improve energy efficiency during the operation mode of technological equipment. The benchmarking methodology is used for analysis of results. Internal and external factors and indicators, which affect energy management potential in pellet production are analysed. Analysis of external factors is based on the state legal framework regulating the development of the energy sector. Methodology on the analysis of energy demand includes the internal energy management of an enterprise. The experimental results discussed in this paper show that particular steps, which are oriented to specific use of technological equipment, could play significant role in energy efficiency improvement in industry which is illustrated by the pre-milling process in the pellet production system using power.

  15. MONEY DEMAND: A STUDY ON THE INDONESIAN INFLUENTIAL FACTORS

    Directory of Open Access Journals (Sweden)

    Nano Prawoto

    2011-09-01

    Full Text Available The role of money demand in monetary policy is indisputable. This study analyzes the determinants of Indonesian money demand. It uses Insukindro-Error Correction Model, based on Keynesian and Monetarist theories. It finds that model based on Monetarist theory is preferable. Estimation on the chosen model suggests that money demand for real currency is influenced, in the short term, by total wealth, consumer price index, the red letter religious day, monetary crisis, and in the long term, by domestic interest rates, foreign interest rates, consumer price index, and stock price index. In addition, monetary policy using Certificate of Bank Indonesia, does not influence money demand.Keywords:     Money demand, keynesian and monetarist model, insukindro-error correction modelJEL classification numbers: E41, E49

  16. Identification of risk factors related to perceived unmet demands in patients with chronic stroke

    NARCIS (Netherlands)

    de Port, I. G. L. Van; Van den Bos, G. A. M.; Voorendt, M.; Kwakkel, G.; Lindeman, E.

    2007-01-01

    Purpose. To investigate the prevalence of unmet demands concerning autonomy and participation and to identify risk factors related to these unmet demands in patients with chronic stroke. Method. A cross-sectional study of 147 patients three years after stroke. We assessed perceived unmet care demand

  17. Rule-based expert system to establish the linkage between yarn twist factor and end-use.

    CSIR Research Space (South Africa)

    Dlodlo, N

    2009-09-01

    Full Text Available This paper describes the concepts and development of a rule-based expert system to establish the optimum linkage between the yarn twist factor and end-use of a yarn and determine the appropriate twist for the particular yarn. The quality of a yarn...

  18. Demand Side Management in Pellet Production: Internal and External Factors

    Directory of Open Access Journals (Sweden)

    Vigants Haralds

    2014-12-01

    Full Text Available This paper demonstrates a demand side management case study: how to save energy and how research and data analysis help to create an energy management system in a pellet production facility; and shows ways to implement the EU energy efficiency directive in production facilities. The study carried out in this research serves as a far-reaching step that can be taken to improve energy efficiency during the operation mode of technological equipment. The benchmarking methodology is used for analysis of results.

  19. 电力需求侧响应利益联动机制的系统动力学模拟%Simulating the electric demand response profit linkage mechanism by system dynamics

    Institute of Scientific and Technical Information of China (English)

    王建军; 李莉; 谭忠富; 牛东晓

    2011-01-01

    Because implementing demand response in China is not conductive for the electric power supply company to recover their costs, it is necessary to establish a profit linkage mechanism for linking the electric power generators' profits and electric power supply companies' loss. This will greatly promote the enthusiasm of electric power supply company. A system dynamics model is established to simulate the effects of this profit linkage mechanism on the whole electric power system. The simulating system divided the demand response profit chain into customer subsystem, electric power grid subsystem and electric power generators subsystem. The internal and external relationship among the relating factors was researched by modeling layer by layer. The simulation results show that if the profit linkage mechanism is designed rationally, demand response will play its largest role, and all the related bodies in the electric power system will be benefited, the electric power generators should also actively support this mechanism, for their negative response will not only hurt other bodies, but also hurt themselves.%考虑到在我国实施需求侧响应可能使得电网企业不能有效回收需求侧响应的成本,且由于发电公司实际上是需求侧响应的最大受益者,因此需要在电网企业和发电公司之间建立一个利益联动机制.运用系统动力学模型模拟发电公司和电网公司联动的行为对电力系统产生的效果,来证明这种利益联动机制存在的必要性.模拟系统将需求侧响应的利益链条分为用户子系统、电网子系统和发电子系统三个部分,通过层层建模剖析了各子系统内部和外部影响因素之间的关系.以某市电网的基础数据为例进行模型,模拟结果表明,如果设计合理,需求侧响应将为整个电力系统带来巨大的效益,而且发电公司应该积极参与到该机制中,因为他们的消极对待不仅会给其它主体带来不利影响,

  20. Working conditions as risk factors for disability retirement: a longitudinal register linkage study

    Directory of Open Access Journals (Sweden)

    Lahelma Eero

    2012-04-01

    Full Text Available Abstract Background Early retirement due to disability is a public health and work environment problem that shortens working careers. Transition to disability retirement is based on ill-health, but working conditions are also of relevance. We examined the contributions of work arrangements, physical working conditions and psychosocial working conditions to subsequent disability retirement. Methods The data were derived from the Helsinki Health Study cohort on employees of the City of Helsinki, Finland. Information on working conditions was obtained from the baseline surveys conducted in 2000, 2001 and 2002. These data were linked with register data on disability retirement and their main diagnoses obtained from the Finnish Centre for Pensions. Follow up by the end of 2008 yielded 525 disability retirement events. The analysed data included 6525 participants and 525 disability retirement events. Hazard ratios (HR and 95% confidence intervals (95% CI were calculated from Cox regression analysis. Results Several working conditions showed own associations with disability retirement before adjustment. After adjustment for all working conditions, the primary risk factors for all-cause disability retirement were physical workload among women (HR 2.02, 95% CI 1.57-2.59 and men (HR 2.00, 95% CI 1.18-3.38, and low job control among women (HR 1.60, 95% CI 1.29-1.99. In addition, for disability retirement due to musculoskeletal causes, the risk factors were physical workload and low job control. For disability retirement due to mental causes the risk factors were computer work and low job control. Furthermore, occupational class was a risk factor for disability retirement due to all causes and musculoskeletal diseases. Conclusions Among various working conditions, those that are physically demanding and those that imply low job control are potential risk factors for disability retirement. Improving the physical working environment and enhancing control over

  1. Measures of Trait Mindfulness:Convergent Validity, Shared Dimensionality, and Linkages to the Five-Factor Model

    Directory of Open Access Journals (Sweden)

    A. B. Siegling

    2014-10-01

    Full Text Available This study investigated, and partially aimed to replicate, important construct validity aspects and the homogeneity of trait mindfulness measures. Specifically, the study set out to examine whether a single dimension can explain the shared variance among these measures as well as the extent to which they converge with one another and in terms of their linkages to the Five-Factor Model (FFM. Two samples completed all trait measures of the construct and one of them additionally completed a measure of the Big Five personality traits. Results showed that a single dimension explains the shared variance among measures based on the original, Eastern conceptualization of mindfulness, although not all of them seem to represent this construct comprehensively. Intercorrelations, dimensionality analysis, as well as linkages to the FFM indicated that the Eastern and Western conceptualizations, and their respective measures, reflect distinct constructs. However, the amount of variance overlap with the FFM was similar across the two conceptualizations.

  2. Nonsyndromic cleft lip and palate: No evidence of linkage to HLA or factor 13A

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, J.T.; Yaping Wang; Connor, B.; Daiger, S.P. (Univ. of Texas, Houston (United States)); Blanton, S.H. (Univ. of Texas, Houston (United States) Univ. of Virginia, Charlottesville (United States))

    1993-06-01

    Nonsyndromic cleft lip with or without cleft palate (CLP) is a common craniofacial anomaly, the etiology of which is not known. Population studies have shown that a large proportion of cases occur sporadically. Recently, segregation analyses applied to CLP families have demonstrated that an autosomal dominant/codominant gene(s) may cause clefting in cases. Associations of autosomal dominant CLP and nonsyndromic cleft palate (CP) with HLA and F13A genes on chromosome 6p have been suggested previously. Linkage to these two areas on chromosome 6p were tested in 12 autosomal dominant families with CLP. With a LOD score of [minus]2 or less for exclusion, no evidence of linkage was found to four chromosome 6p markers. Multipoint analysis showed no evidence of a clefting locus in this region spanning 54 cM on chromosome 6p in these CLP families. 30 refs., 2 figs., 1 tab.

  3. Exploring linkages between socio‐demographic factors and customer loyalty in India

    OpenAIRE

    Sita Mishra; Sai Prasad

    2014-01-01

    Customer loyalty for specific brands has been an important point in marketing planning. In recent years many organizations have identified the need to become more customer oriented with increased global competition. Marketers have realized the importance of building long‐term and sustainable customer relationships that add value both for the customer and the company. This paper attempts to understand linkages between consumers’ brand loyalty with respect to various product categories and soci...

  4. THE IMPACT OF HACCP ON FACTOR DEMAND AND OUTPUT SUPPLY ELASTICITIES OF RED MEAT

    OpenAIRE

    Nganje, William E.; Mazzocco, Michael A.

    2003-01-01

    This study uses firm-level data during the hazard analysis critical control point (HACCP) implementation period (1997 - 2000) to analyze the impact of HACCP on input demand and output supply elasticities of firms in the red meat industry and derive implications for efficiency and moral hazard issues associated with the implementation of HACCP systems. The results show that HACCP causes factor demand for labor, material, and capital to be less inelastic while the elasticity of output supply di...

  5. Latent factor structure of a behavioral economic cigarette demand curve in adolescent smokers.

    Science.gov (United States)

    Bidwell, L Cinnamon; MacKillop, James; Murphy, James G; Tidey, Jennifer W; Colby, Suzanne M

    2012-11-01

    Behavioral economic demand curves, or quantitative representations of drug consumption across a range of prices, have been used to assess motivation for a variety of drugs. Such curves generate multiple measures of drug demand that are associated with cigarette consumption and nicotine dependence. However, little is known about the relationships among these facets of demand. The aim of the study was to quantify these relationships in adolescent smokers by using exploratory factor analysis to examine the underlying structure of the facets of nicotine incentive value generated from a demand curve measure. Participants were 138 adolescent smokers who completed a hypothetical cigarette purchase task, which assessed estimated cigarette consumption at escalating levels of price/cigarette. Demand curves and five facets of demand were generated from the measure: Elasticity (i.e., 1/α or proportionate price sensitivity); Intensity (i.e., consumption at zero price); O(max) (i.e., maximum financial expenditure on cigarettes); P(max) (i.e., price at which expenditure is maximized); and Breakpoint (i.e., the price that suppresses consumption to zero). Principal components analysis was used to examine the latent structure among the variables. The results revealed a two-factor solution, which were interpreted as "Persistence," reflecting insensitivity to escalating price, and "Amplitude," reflecting the absolute levels of consumption and price. These findings suggest a two factor structure of nicotine incentive value as measured via a demand curve. If supported, these findings have implications for understanding the relationships among individual demand indices in future behavioral economic studies and may further contribute to understanding of the nature of cigarette reinforcement.

  6. Job demand and cardiovascular disease risk factor in white-collar workers.

    Science.gov (United States)

    Song, Young Kyu; Lee, Kang Koo; Kim, Hyoung Ryoul; Koo, Jung-Wan

    2010-01-01

    This study was conducted to determine whether job demand played a role as a risk factor of cardiovascular diseases by comparing changes of blood pressure, heart rate and rate pressure product (RPP) showing myocardial oxygen consumption (MVO2) according to levels of job demand. This cross-sectional study divided 177 male white-collar workers without a cardiovascular or metabolic disease according to their job demand and analyzed their body composition and results of graded exercise testing. There was no significant difference in height, body weight, body mass index (BMI), waist to hip ratio (WHR) and body fat percentage according to job demand. Maximal oxygen consumption (VO2max) and anaerobic threshold (AT) also did not show a significant difference. However, systolic blood pressures at the seventh and eighth stages over AT during exercise were significantly different and RPP was found to have a significant difference overall according to the job demand (ppressure in physical activities or at exercise intensity over AT and reduced energy efficiency of myocardium during physical activities. The results suggest that high job demand may be a risk factor of cardiovascular diseases.

  7. Factors buffering against the effects of job demands: how does age matter?

    Science.gov (United States)

    Besen, Elyssa; Matz-Costa, Christina; James, Jacquelyn B; Pitt-Catsouphes, Marcie

    2015-02-01

    Given the increasing role that paid work is likely to play in older adulthood in the coming decades, the goal of this study was to understand the circumstances under which work is related to mental health for older adults and whether these circumstances differ by age. Using a multiworksite sample of 1,812 U.S. workers age 18 to 81, we use the life-span theory of control to hypothesize that older and younger workers may benefit differentially from job and personal control in the context of high job demands. Results suggest that for younger workers with high personal control, job control buffers the impact of job demands on mental health. For older workers, personal control alone buffers the impact of job demands on mental health. This study adds to previous research by addressing how the factors thought to buffer against the effects of job demands differ cross-sectionally by age.

  8. Demand Forecasting at Low Aggregation Levels using Factored Conditional Restricted Boltzmann Machine

    DEFF Research Database (Denmark)

    Mocanu, Elena; Nguyen, Phuong H.; Gibescu, Madeleine

    2016-01-01

    The electrical demand forecasting problem can be regarded as a nonlinear time series prediction problem depending on many complex factors since it is required at various aggregation levels and at high temporal resolution. To solve this challenging problem, various time series and machine learning...... developed deep learning model for time series prediction, namely Factored Conditional Restricted Boltzmann Machine (FCRBM), and extend it for electrical demand forecasting. The assessment is made on the EcoGrid dataset, originating from the Bornholm island experiment in Denmark, consisting of aggregated...

  9. Analysis Of Factors Affecting Demand Red Chili Pepper Capsicum Annum L In Solok And Effort Fulfillment

    Directory of Open Access Journals (Sweden)

    Zulfitriyana

    2015-08-01

    Full Text Available Research on the analysis of the factors that influence the demand for red chilli Capsicum annuum L in Solok and compliance efforts implemented in March s.d April 2016. The purpose of this study consisted of 1 analyze the factors affecting the demand for red chili in Solok 2 analyze the elasticity of demand for red chili in Solok 3 know the effort that can be done to meet the demand of red chilli in Solok. To achieve the objectives of the first and second use secondary data for 15 fifteen years and to achieve the objectives the third used primary data. The method used is descriptive analytical method a method that is used to describe phenomena that exist which takes place in the present or past. The variables were observed in this study is the X1 price of red chilli X2 the price of green chili X3 onion prices X4 population X5 income and Y the number of requests red chili which is then analyzed by multiple linear regression elasticity of demand and SWOT. The results of that research addressing the factors that influence the demand for red chili in Solok is the price of red chilli itself the price of green chili as a substitute goods the number of population and income while onion prices affect the amount of red chili demand in Solok. But simultaneously variable X1 red chili prices X2 the price of green chili X3 onion prices X4 population and X5 income strongly influence demand red chili in Solok where the F test results show that F count F table 212.262 3600 with a significance level 0.000 0.010 and the most influential variable is the variable X4 population with the greatest value of beta Coefficients is 1100. Based on analysis of the elasticity of demand is known that red chili pepper is a normal good is inelastic to price elasticity coefficient value amp603p of -0.120. Green chili is substituting goods and shallots are complements of red chili with cross elasticity coefficient amp603px1 and amp603px2 respectively by 0293 and -0.635. While the

  10. Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: demography, chromosome recombination frequency and selection.

    Science.gov (United States)

    Zavattari, P; Deidda, E; Whalen, M; Lampis, R; Mulargia, A; Loddo, M; Eaves, I; Mastio, G; Todd, J A; Cucca, F

    2000-12-12

    Linkage disequilibrium (LD) mapping of disease genes is complicated by population- and chromosome-region-specific factors. We have analysed demographic factors by contrasting intermarker LD results obtained in a large cosmopolitan population (UK), a large genetic isolate (Sardinia) and a subisolate (village of Gavoi) for two regions of the X chromosome. A dramatic increase of LD was found in the subisolate. Demographic history of populations therefore influences LD. Chromosome-region-specific effects, namely the pattern and frequency of homologous recombination, were next delineated by the analysis of chromosome 6p21, including the HLA region. Patterns of global LD in this region were very similar in the UK and Sardinian populations despite their entirely distinct demographies, and correlate well with the pattern of recombinations. Nevertheless, haplotypes extend across recombination hot spots indicative of selection of certain haplotypes. Subisolate aside, chromosome-region-specific differences in LD patterns appear to be more important than the differences in intermarker LD between distinct populations.

  11. Assessment of patients' awareness and factors influencing patients' demands for sedation in endodontics.

    Science.gov (United States)

    Huh, Yoo Kyeom; Montagnese, Thomas A; Harding, Jarrod; Aminoshariae, Anita; Mickel, Andre

    2015-02-01

    Endodontic therapy is perceived by many as a procedure to be feared. Many studies have reported that fear and anxiety are major deterrents to seeking dental care in general, but only a few deal with the use of sedation in endodontic therapies. The purpose of this study was to assess patients' awareness of and factors influencing the potential demand for sedation in endodontics. We hypothesized that there is an association between demographic factors and the demand for sedation in endodontics. A survey consisting of 24 questions was given to patients 18 years and older who presented to the graduate endodontic clinic. Results were collected and statistically analyzed. Thirty-six percent of patients reported that their perception of sedation was being put to sleep, and 27% perceived it as related to or reducing pain. Concerns associated with endodontic therapy were the fear of pain (35%), fear of needles (16%), difficulty getting numb (10%), and anxiety (7%). The 2 major demographic factors that influenced the demand for sedation were cost and the level of anxiety (P endodontic therapy if the option of sedation was available. The demand for sedation in endodontics is high. Patients' understanding of sedation varies. More patients would consider having endodontic procedures if sedation was available. The provision of sedation by endodontists could result in more patients accepting endodontic therapies. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  12. Factors affecting linkage to care and engagement in care for newly diagnosed HIV-positive adolescents within fifteen adolescent medicine clinics in the United States.

    Science.gov (United States)

    Philbin, Morgan M; Tanner, Amanda E; DuVal, Anna; Ellen, Jonathan M; Xu, Jiahong; Kapogiannis, Bill; Bethel, Jim; Fortenberry, J Dennis

    2014-08-01

    Early linkage to care and engagement in care are critical for initiation of medical interventions. However, over 50 % of newly diagnosed persons do not receive HIV-related care within 6 months of diagnosis. We evaluated a linkage to care and engagement in care initiative for HIV-positive adolescents in 15 U.S.-based clinics. Structural and client-level factors (e.g. demographic and behavioral characteristics, clinic staff and location) were evaluated as predictors of successful linkage and engagement. Within 32 months, 1,172/1,679 (69.8 %) of adolescents were linked to care of which 1,043/1,172 (89 %) were engaged in care. Only 62.1 % (1,043/1,679) of adolescents were linked and engaged in care. Linkage to care failure was attributed to adolescent, provider, and clinic-specific factors. Many adolescents provided incomplete data during the linkage process or failed to attend appointments, both associated with failure to linkage to care. Additional improvements in HIV care will require creative approaches to coordinated data sharing, as well as continued outreach services to support newly diagnosed adolescents.

  13. Effect of Response Reduction Factor on Peak Floor Acceleration Demand in Mid-Rise RC Buildings

    Science.gov (United States)

    Surana, Mitesh; Singh, Yogendra; Lang, Dominik H.

    2017-06-01

    Estimation of Peak Floor Acceleration (PFA) demand along the height of a building is crucial for the seismic safety of nonstructural components. The effect of the level of inelasticity, controlled by the response reduction factor (strength ratio), is studied using incremental dynamic analysis. A total of 1120 nonlinear dynamic analyses, using a suite of 30 recorded ground motion time histories, are performed on mid-rise reinforced-concrete (RC) moment-resisting frame buildings covering a wide range in terms of their periods of vibration. The obtained PFA demands are compared with some of the major national seismic design and retrofit codes (IS 1893 draft version, ASCE 41, EN 1998, and NZS 1170.4). It is observed that the PFA demand at the building's roof level decreases with increasing period of vibration as well as with strength ratio. However, current seismic building codes do not account for these effects thereby producing very conservative estimates of PFA demands. Based on the identified parameters affecting the PFA demand, a model to obtain the PFA distribution along the height of a building is proposed. The proposed model is validated with spectrum-compatible time history analyses of the considered buildings with different strength ratios.

  14. Study on Linkage and Collaboration of Food Consumption Demand and Food Logistics%食品消费需求与食品物流关联机制及协同发展对策研究

    Institute of Scientific and Technical Information of China (English)

    崔小俊

    2014-01-01

    In this paper, we elaborated on the basic concept of food consumption and food logistics, then analyzed the linkage and mechanism of action between the food consumption demand and food logistics, and on such basis proposed the strategy to promote the collaborative development of the two.%阐述了食品消费与食品物流的基本概念,对食品消费需求与食品物流间的关联、作用机制进行了分析,在此基础上提出了促进食品消费需求与食品物流协同发展的策略。

  15. Inventories, Factor Demand and Capacity Utilization : the Long and Short Run Structure

    OpenAIRE

    1995-01-01

    An ECM is derived from first order conditions of a factor demand model. Decisions on inventory stock and capacity utilization are (endogenously) modelled, by which a large systems of equations results. Within this system the exogeneity of real factor prices as well as sales in tested. The role of inventory stock in the long run, i.e. as a precautionary measure (according to Holt, Modigliani, Muth and Simon (1960) and/or as a production factor (Kydland and Prescott (1982), Christiano (1988) ar...

  16. Of River Linkage and Issue Linkage

    NARCIS (Netherlands)

    Warner, Jeroen Frank

    2016-01-01

    It is a truism in mainstream International Relations that issue linkage promotes regime formation and integration. The present article applies this idea to the transboundary lower river Meuse and finds its history of integration to be a tortuous one. Contextual political factors have at times

  17. Relative-Price Changes and Demand Factors in the Period of Quantitative Easing in Japan

    OpenAIRE

    Hayo, Bernd; Ono, Hiroyuki

    2010-01-01

    Concentrating on the period of quantitative easing in Japan, this paper reexamines the correlation between the asymmetry of sectoral relative-price changes and the aggregate inflation rate. This correlation is widely interpreted as evidence that short-run inflation is determined by supply-side factors; however, we study whether, in addition to the inflation rate, monetary environment and aggregate demand explain this correlation. Using producer price index data, we show, first, that the posit...

  18. An application of ANP for ranking different factors influencing on demand for auto parts

    Directory of Open Access Journals (Sweden)

    Ali Zarepour

    2014-04-01

    Full Text Available This paper presents an empirical investigation to study different factors influencing auto parts in different regions of Iran. The study has asked some experts who worked for the biggest auto parts supplier named SaipaYadak to express their insights about important factors influencing demand for auto parts in different region and their insights have grouped into four categories of parts related issues, weather conditions, regional as well as cultural factors. The study has been applied in five different regions of country including central, south, north, west and east. The study has used analytical network process (ANP to rank different factors and the results indicate that regional factors is the most important item followed by cultural issues, auto parts and weather conditions.

  19. Early postnatal hyperglycaemia is a risk factor for treatment-demanding retinopathy of prematurity

    DEFF Research Database (Denmark)

    Slidsborg, Carina; Jensen, Louise Bering; Rasmussen, Steen Christian

    2017-01-01

    BACKGROUND: To investigate whether neonatal hyperglycaemia in the first postnatal week is associated with treatment-demanding retinopathy of prematurity (ROP). METHODS: This is a Danish national, retrospective, case-control study of premature infants (birth period 2003-2006). Three national regis......: An independent association was found between the occurrence of hyperglycaemic events during the first postnatal week and later development of treatment-demanding ROP, when adjusted for known risk factors.......BACKGROUND: To investigate whether neonatal hyperglycaemia in the first postnatal week is associated with treatment-demanding retinopathy of prematurity (ROP). METHODS: This is a Danish national, retrospective, case-control study of premature infants (birth period 2003-2006). Three national...... was borderline significant (t-test; p=0.047). Hyperglycaemic events (indexed value) were statistically significantly different between the two study groups (Mann-Whitney U test; pindependent risk factor (OR: 1.022; 95% CI 1.002 to 1.042; p=0.031). CONCLUSION...

  20. The Role of Institutional Factors Over the National Insurance Demand: Theoretical Approach and Econometric Estimations

    Directory of Open Access Journals (Sweden)

    Simona Laura DRAGOȘ

    2013-06-01

    Full Text Available The insurance sector becomes a more and more important component for the national economic and financial development. Nevertheless, the consumption and the density, both for life and non-life insurances, reveal a great variation across countries. Academic literature treats frequently the importance of the economic and demographic factors. This study evaluates the determining institutional factors of the insurance demand using OLS Multiple Regressions models on a sample of 31 European countries. The econometric estimates, according to the theory, show that a country’s level of corruption is decisive for the development of the non-life insurances. For the life insurances, business freedom, fiscal freedom and government spending are the most relevant explanatory variables. The article emphasizes the mechanism through which the significant institutional factors influence the insurance density from a country.

  1. Extending social health insurance to the informal sector in Kenya. An assessment of factors affecting demand.

    Science.gov (United States)

    Mathauer, Inke; Schmidt, Jean-Olivier; Wenyaa, Maurice

    2008-01-01

    This paper contributes to analysing and understanding the demand for (social) health insurance of informal sector workers in Kenya by assessing their perceptions and knowledge of and concerns regarding health insurance and the Kenyan National Hospital Insurance Fund (NHIF). It serves to explore how informal sector workers could be integrated into the NHIF. To collect data, focus group discussions were held with organized groups of informal sector workers of different types across the country, backed up by a self-administered questionnaire completed by heads of NHIF area branch offices. It was found that the most critical barrier to NHIF enrollment is the lack of knowledge of informal sector workers about the NHIF, its enrollment option and procedures for informal sector workers. Inability to pay is a critical factor for some, but people were, in principle, interested in health insurance, and thus willing to pay for it. In sum, the mix of demand-side determinants for enrolling in the NHIF is not as complex as expected. This is good news, as these demand-side determinants can be addressed with a well-designed strategy, focusing on awareness raising and information, improvement of insurance design features and setting differentiated and affordable contribution rates.

  2. Evaluation of socio-economic factors affecting the demand for health

    Directory of Open Access Journals (Sweden)

    Abdosaleh Jafari

    2014-04-01

    Full Text Available Introduction: Individual health has been proved to be under the influence of various factors such as the use of health care services, diet, smoking and alcohol, physical environment, and health-related behaviors. Therefore, the main determinants of health are factors such as income, education, and access to health services, and systematic changes in these factors lead to socio-economic injustice in health. The present study was carried out through library and internet search. Medline and Google Scholar databases were also utilized. Combining Contents and Results: According to the present study, an increase in health input expenses would inevitably lead to aggravation of the health situation and decrease in income would result in the worst health status of the poor. Moreover, people with higher education use less health inputs; however, they enjoy higher status than those with lower educational levels. Conclusion: Health demand approach provides only a part of the information needed for policy-makers and decision-makers in health system. Theoretical and empirical analyses of the health claim could indicate that policy actions are likely to be more effective in overcoming barriers to health but are not capable of determining which one is likely to be more cost-effective . The demand for information about the health only provides the necessary tools about the benefits of special policy making decisions. So the tool should be combined with other techniques including cost-effectiveness and cost-benefit analyses.

  3. Effects off system factors on the economics of and demand for small solar thermal power systems

    Science.gov (United States)

    1981-01-01

    Market penetration as a function time, SPS performance factors, and market/economic considerations was estimated, and commercialization strategies were formulated. A market analysis task included personal interviews and supplemental mail surveys to acquire statistical data and to identify and measure attitudes, reactions and intentions of prospective SPS users. Interviews encompassed three ownership classes of electric utilities and industrial firms in the SIC codes for energy consumption. A market demand model was developed which utilized the data base developed, and projected energy price and consumption data to perform sensitivity analyses and estimate potential market for SPS.

  4. Society demands for the quality of education as a factor of modern education space forming

    Directory of Open Access Journals (Sweden)

    Ivanova Svetlana V.

    2016-01-01

    Full Text Available The authors research the problems of increasing in modern conditions society demands for qualitative characteristics of education services. The quality of education is considered as one of the determining factors of forming educational space. The paper analyzes the influence of social and economic conditions inherent in the post-industrial era on forming and transforming of education space at the modern stage of society development, shows the ways to overcome emerging contradictions. The authors pay special attention to the significance of project approach in solving the problems of improving education quality.

  5. Modeling factors influencing the demand for emergency department services in ontario: a comparison of methods

    Directory of Open Access Journals (Sweden)

    Meaney Christopher

    2011-08-01

    Full Text Available Abstract Background Emergency departments are medical treatment facilities, designed to provide episodic care to patients suffering from acute injuries and illnesses as well as patients who are experiencing sporadic flare-ups of underlying chronic medical conditions which require immediate attention. Supply and demand for emergency department services varies across geographic regions and time. Some persons do not rely on the service at all whereas; others use the service on repeated occasions. Issues regarding increased wait times for services and crowding illustrate the need to investigate which factors are associated with increased frequency of emergency department utilization. The evidence from this study can help inform policy makers on the appropriate mix of supply and demand targeted health care policies necessary to ensure that patients receive appropriate health care delivery in an efficient and cost-effective manner. The purpose of this report is to assess those factors resulting in increased demand for emergency department services in Ontario. We assess how utilization rates vary according to the severity of patient presentation in the emergency department. We are specifically interested in the impact that access to primary care physicians has on the demand for emergency department services. Additionally, we wish to investigate these trends using a series of novel regression models for count outcomes which have yet to be employed in the domain of emergency medical research. Methods Data regarding the frequency of emergency department visits for the respondents of Canadian Community Health Survey (CCHS during our study interval (2003-2005 are obtained from the National Ambulatory Care Reporting System (NACRS. Patients' emergency department utilizations were linked with information from the Canadian Community Health Survey (CCHS which provides individual level medical, socio-demographic, psychological and behavioral information for

  6. Risk factors for ischaemic heart disease mortality among men with different occupational physical demands. A 30-year prospective cohort study

    DEFF Research Database (Denmark)

    Holtermann, Andreas; Mortensen, Ole Steen; Søgaard, Karen

    2012-01-01

    Objectives Men with high physical work demands have elevated cardiovascular strain, which may lead to enhanced atherosclerosis. Theoretically, the impact of risk factors for ischaemic heart disease (IHD) may thus depend on physical work demands. The authors investigated this hypothesis. Design Pr...

  7. Supply and Demand Factors in Understanding the Educational Earnings Differentials: West Germany and the United States

    Directory of Open Access Journals (Sweden)

    Gulgun Bayaz Ozturk

    2011-12-01

    Full Text Available This paper uses data from the March Current Population Survey and German Socio-Economic Panel to investigate the role of market forces and the institutional constraints in explaining the educational earnings differentials in the United States and West Germany. We make use of simple supply and demand framework to differentiate the effects of market forces from wage-setting institutions. Results indicate that differential growth in the relative employment of skilled workers is responsible for the differences in returns to skill in both countries over the period of analysis. In particular, rising educational attainment is the major factor underlying the changes in the employment of skilled workers in each country and it is followed by institutional factors. However, in addition to the differential growth in relative demand for skilled labor, differences in wage-setting institutions explain most of the cross-country differences in skill premia. We also provide evidence for polarization of jobs which is a recent phenomenon in both labor markets.

  8. Influence of maternal and perinatal factors on subsequent hospitalisation for asthma in children: evidence from the Oxford record linkage study

    Directory of Open Access Journals (Sweden)

    Wotton Clare J

    2010-03-01

    Full Text Available Abstract Background There is much interest in the possibility that perinatal factors may influence the risk of disease in later life. We investigated the influence of maternal and perinatal factors on subsequent hospital admission for asthma in children. Methods Analysis of data from the Oxford record linkage study (ORLS to generate a retrospective cohort of 248 612 records of births between 1970 and 1989, with follow-up to records of subsequent hospital admission for 4 017 children with asthma up to 1999. Results Univariate analysis showed significant associations between an increased risk of admission for asthma and later years of birth (reflecting the increase in asthma in the 1970s and 1980s, low social class, asthma in the mother, unmarried mothers, maternal smoking in pregnancy, subsequent births compared with first-born, male sex, low birth weight, short gestational age, caesarean delivery, forceps delivery and not being breastfed. Multivariate analysis, identifying each risk factor that had a significant effect independently of other risk factors, confirmed associations with maternal asthma (odds ratio (OR 3.1, 95% confidence interval 2.7-3.6, male sex (versus female, 1.8, 1.7-2.0, low birth weight (1000-2999 g versus 3000-3999 g, 1.2, 1.1-1.3, maternal smoking (1.1, 1.0-1.3 and delivery by caesarean section (1.2; 1.0-1.3. In those first admitted with asthma under two years old, there were associations with having siblings (e.g. second child compared with first-born, OR 1.3, 1.0-1.7 and short gestational age (24-37 weeks versus 38-41 weeks, 1.6, 1.2-2.2. Multivariate analysis confined to those admitted with asthma aged six years or more, showed associations with maternal asthma (OR 3.8, 3.1-4.7, age of mother (under 25 versus 25-34 at birth, OR 1.16, 1.03-1.31; over 35 versus 25-34, OR 1.4, 1.1-1.7; high social class was protective (1 and 2, compared with 3, 0.72; 0.63-0.82. Hospital admission for asthma in people aged over six was more

  9. Association between job strain (high demand-low control and cardiovascular disease risk factors among petrochemical industry workers

    Directory of Open Access Journals (Sweden)

    Siamak Poorabdian

    2013-08-01

    Full Text Available Objective: One of the practical models for assessment of stressful working conditions due to job strain is "job demand and control" or Karasek's job strain model. This model explains how adverse physical and psychological effects including cardiovascular disease risk factors can be established due to high work demand. The aim was to investigate how certain cardiovascular risk factors including body mass index (BMI, heart rate, blood pressure, serum total cholesterol levels, and cigarette smoking are associated with job demand and control in workers. Materials and Methods: In this cohort study, 500 subjects completed "job demand and control" questionnaires. Factor analysis method was used in order to specify the most important "job demand and control" questions. Health check-up records of the workers were applied to extract data about cardiovascular disease risk factors. Ultimately, hypothesis testing, based on Eta, was used to assess the relationship between separated working groups and cardiovascular risk factors (hypertension and serum total cholesterol level. Results: A significant relationship was found between the job demand-control model and cardiovascular risk factors. In terms of chisquared test results, the highest value was assessed for heart rate (Chi2 = 145.078. The corresponding results for smoking and BMI were Chi2 = 85.652 and Chi2 = 30.941, respectively. Subsequently, Eta result for total cholesterol was 0.469, followed by hypertension equaling 0.684. Moreover, there was a significant difference between cardiovascular risk factors and job demand-control profiles among different working groups including the operational group, repairing group and servicing group. Conclusion: Job control and demand are significantly related to heart disease risk factors including hypertension, hyperlipidemia, and cigarette smoking.

  10. Pricing of common cosmetic surgery procedures: local economic factors trump supply and demand.

    Science.gov (United States)

    Richardson, Clare; Mattison, Gennaya; Workman, Adrienne; Gupta, Subhas

    2015-02-01

    The pricing of cosmetic surgery procedures has long been thought to coincide with laws of basic economics, including the model of supply and demand. However, the highly variable prices of these procedures indicate that additional economic contributors are probable. The authors sought to reassess the fit of cosmetic surgery costs to the model of supply and demand and to determine the driving forces behind the pricing of cosmetic surgery procedures. Ten plastic surgery practices were randomly selected from each of 15 US cities of various population sizes. Average prices of breast augmentation, mastopexy, abdominoplasty, blepharoplasty, and rhytidectomy in each city were compared with economic and demographic statistics. The average price of cosmetic surgery procedures correlated substantially with population size (r = 0.767), cost-of-living index (r = 0.784), cost to own real estate (r = 0.714), and cost to rent real estate (r = 0.695) across the 15 US cities. Cosmetic surgery pricing also was found to correlate (albeit weakly) with household income (r = 0.436) and per capita income (r = 0.576). Virtually no correlations existed between pricing and the density of plastic surgeons (r = 0.185) or the average age of residents (r = 0.076). Results of this study demonstrate a correlation between costs of cosmetic surgery procedures and local economic factors. Cosmetic surgery pricing cannot be completely explained by the supply-and-demand model because no association was found between procedure cost and the density of plastic surgeons. © 2015 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  11. Factors affecting the unmet demand for pharmacists: state-level analysis.

    Science.gov (United States)

    Taylor, Thomas N; Knapp, Katherine K; Barnett, Mitchell J; Shah, Bijal M; Miller, Laura

    2013-01-01

    To describe the relationship between state-level Aggregate Demand Index (ADI) data and market factors reflecting both supply and demand: unemployment rates, pharmacy graduates, community pharmacy prescription growth rates, and Medicare Part D. Cross-sectional time series analysis using state-level data. U.S. labor market for pharmacists, from 2001 to 2010. Model ADI data for states (dependent variable) against five independent variables: previous year ADI, unemployment rates, pharmacy graduates, prescription growth rates, and Medicare Part D. Significance and predictive ability of the model, sign of the variables studied, and R2. In the two-way (state and time) fixed-effects model, all variables were significant and R2 was 0.79. Contributions to state-level ADIs were, in rank order, previous year ADI, unemployment rates, pharmacy graduates, and prescription growth rates. The model predicted 2010 ADI values for 44 of 51 states within ±10%. The model depicts the independent contributions of each variable for the short (∼1 year) and longer term. Although the nature of ADI data precludes quantitative predictions about the pharmacist job market, the model results show marketplace directions (up or down) and comparative impacts. The model demonstrated that unemployment rates, pharmacy graduates, prescription growth rates, and Medicare Part D contributed significantly to state-level ADIs between 2001 and 2010. The relationships uncovered should be monitored and reexamined as new data emerge in order to anticipate the directions of the pharmacist job market.

  12. Future Protein Supply and Demand: Strategies and Factors Influencing a Sustainable Equilibrium

    Directory of Open Access Journals (Sweden)

    Maeve Henchion

    2017-07-01

    Full Text Available A growing global population, combined with factors such as changing socio-demographics, will place increased pressure on the world’s resources to provide not only more but also different types of food. Increased demand for animal-based protein in particular is expected to have a negative environmental impact, generating greenhouse gas emissions, requiring more water and more land. Addressing this “perfect storm” will necessitate more sustainable production of existing sources of protein as well as alternative sources for direct human consumption. This paper outlines some potential demand scenarios and provides an overview of selected existing and novel protein sources in terms of their potential to sustainably deliver protein for the future, considering drivers and challenges relating to nutritional, environmental, and technological and market/consumer domains. It concludes that different factors influence the potential of existing and novel sources. Existing protein sources are primarily hindered by their negative environmental impacts with some concerns around health. However, they offer social and economic benefits, and have a high level of consumer acceptance. Furthermore, recent research emphasizes the role of livestock as part of the solution to greenhouse gas emissions, and indicates that animal-based protein has an important role as part of a sustainable diet and as a contributor to food security. Novel proteins require the development of new value chains, and attention to issues such as production costs, food safety, scalability and consumer acceptance. Furthermore, positive environmental impacts cannot be assumed with novel protein sources and care must be taken to ensure that comparisons between novel and existing protein sources are valid. Greater alignment of political forces, and the involvement of wider stakeholders in a governance role, as well as development/commercialization role, is required to address both sources of

  13. The linkage between work-related factors, employee satisfaction and organisational commitment: Insights from public health professionals

    Directory of Open Access Journals (Sweden)

    Chengedzai Mafini

    2014-02-01

    Full Text Available Orientation: The public health sector in South Africa faces a number of human resource– related inundations. Solving these challenges requires the provision of empirically derived information on these matters.Research purpose: This study investigated the relationship between three work-related factors, person-environment fit, work-family balance and perceived job security, and employee satisfaction and organisational commitment. A conceptual framework that links these factors is proposed and tested.Motivation for the study: The prevalence of employee-related challenges involving public health professionals, as evidenced through industrial action and high labour turnover, amongst others, demands further research in order to generate appropriate solutions.Research approach, design and method: A quantitative design using the survey approach was adopted. A six-section questionnaire was administered to a stratified sample of 287 professionals in three public health institutions in Gauteng, South Africa. Data was analysed using descriptive statistics, exploratory factor analysis, Pearson’s correlation analysis and regression analysis.Main findings: Job security and person-environment fit both positively correlated with and predicted employee satisfaction. The association between work-family balance and employee satisfaction was weak and showed no significant predictive validity. Employee satisfaction was strongly correlated to and predicted organisational commitment.Practical/managerial implications: The findings of the current study may be used by managers in public health institutions to improve the level of organisational commitment amongst professionals in the sector, thus preventing further employee-related challenges that negatively affect the provision of outstanding public health services.Contribution: The study provides current evidence on how both work-related and humanrelated factors could contribute to the prosperity of the public

  14. Linkages between benthic assemblages and physical environmental factors: The role of geodiversity in Eastern Gulf of Finland ecosystems

    Science.gov (United States)

    Kaskela, A. M.; Rousi, H.; Ronkainen, M.; Orlova, M.; Babin, A.; Gogoberidze, G.; Kostamo, K.; Kotilainen, A. T.; Neevin, I.; Ryabchuk, D.; Sergeev, A.; Zhamoida, V.

    2017-06-01

    We analyzed hydrology, geology and benthic species composition to determine benthic habitat distribution patterns in a geologically complex area of the Gulf of Finland, Northern Baltic Sea. The analysis included several datasets describing coastal influence and geodiversity at multiple spatial scales. Geodiversity in this context refers to variation and/or patchiness of benthic substrates and seabed features. Multivariate statistical methods including BEST and LINKTREE routines were used to identify correlative relationships between different ecological variables. Environmental variables (e.g. water depth, Secchi depth, salinity) were either measured by sampling and remote sensing methods or parameterized from geographic and oceanographic data. Benthic assemblages were assayed by both video recordings and zoobenthic sampling (benthic grabs). Statistical analyses identified correlations between benthic datasets and environmental variables, but correlation parameters were not consistent especially with respect to differing zoobenthic and video-based estimates of benthic diversity. The ratio of Secchi depth to water depth showed strong correlation with species distributions observed in video recordings (ρ = 0.56) whereas variables describing broad-scale geodiversity and archipelago gradient (the abundance of islands, ratio of land and sea area) correlated with zoobenthic sample data (generally ρ > 0.30). A model that included independent variables of Secchi depth and terrain roughness within a 20 km radius explained the greatest proportion of spatial variation in zoobenthic sample data (ρ = 0.69). Secchi depth and roughness values were positively correlated with species richness. We designated nine benthic marine landscapes on the basis of these two variables. Linkage tree statistical analysis (LINKTREE) routine utilized zoobenthic sample data as these offered better regional coverage and therefore effectively tracked relationships with other environmental

  15. Improvement of fibrin clot structure after factor VIII injection in haemophilia A patients treated on demand.

    Science.gov (United States)

    Antovic, Aleksandra; Mikovic, Danijela; Elezovic, Ivo; Zabczyk, Michael; Hutenby, Kjell; Antovic, Jovan P

    2014-04-01

    Patients with haemophilia A have seriously impaired thrombin generation due to an inherited deficiency of factor (F)VIII, making them form unstable fibrin clots that are unable to maintain haemostasis. Data on fibrin structure in haemophilia patients remain limited. Fibrin permeability, assessed by a flow measurement technique, was investigated in plasma from 20 patients with severe haemophilia A treated on demand, before and 30 minutes after FVIII injection. The results were correlated with concentrations of fibrinogen, FVIII and thrombin-activatable fibrinolysis inhibitor (TAFI), and global haemostatic markers: endogenous thrombin potential (ETP) and overall haemostatic potential (OHP). Fibrin structure was visualised using scanning electron microscopy (SEM). The permeability coefficient Ks decreased significantly after FVIII treatment. Ks correlated significantly with FVIII levels and dosage, and with ETP, OHP and levels of TAFI. SEM images revealed irregular, porous fibrin clots composed of thick and short fibers before FVIII treatment. The clots had recovered after FVIII replacement almost to levels in control samples, revealing compact fibrin with smaller intrinsic pores. To the best of our knowledge, this is the first description of fibrin porosity and structure before and after FVIII treatment of selected haemophilia patients. It seems that thrombin generation is the main determinant of fibrin structure in haemophilic plasma.

  16. The Role of Demand Factors in Utilization of Professional Care during Childbirth: Perspectives from Yemen

    Science.gov (United States)

    Kempe, Annica; Noor-Aldin Alwazer, Fatoom; Theorell, Töres

    2011-01-01

    Background. Utilization of professional care during childbirth by women in low-income countries is important for the progress towards MDG 5. In Yemen, home births have decreased minimally during the past decades. Objective. The study investigates the influence of socio-demographic, birth outcome and demand factors on women's future preference of a home or institutional childbirth. Method. We interviewed 220 women with childbirth experience in urban/rural Yemen. We performed bivariate chi-square tests and multiple logistic regression analysis. A multistage sampling process was used. Results. The issues of own choice, birth support and birth complications were the most important for women's preference of future location of childbirth. Women who had previously been able to follow their own individual choice regarding birth attendance and/or location of childbirth were six times more likely to plan a future childbirth in the same location and women who received birth support four times more likely. Birth complications were associated with a 2.5-fold decrease in likelihood. Conclusions. To offer women with institutional childbirth access to birth support is crucial in attracting women to professional care during childbirth. Yemeni women's low utilization of modern delivery care should be seen in the context of women's low autonomy and status. PMID:21941663

  17. Views of Health System Experts on Macro Factors of Induced Demand

    Directory of Open Access Journals (Sweden)

    Elahe Khorasani

    2014-01-01

    Conclusions: Results of this research present a framework for analyzing the major causes of induced demand. The causes identified here include complexity of medicine, information mismatch between service providers and consumers, clinical uncertainty, false beliefs, advertisements, insufficient supervision, scarcity of clinical guidelines, weakness of education system, and ignorance of medical ethics. These findings help policymakers to investigate the induced demand phenomenon clear-sighted.

  18. Demand model for production of an enterprise taking into account factor of consumer expectations

    Directory of Open Access Journals (Sweden)

    L.V. Potrashkova

    2012-12-01

    Full Text Available This article presents a dynamic mathematical model of demand for innovative and uninnovative production of enterprises. The model allows to estimate future demand as a result of consumer expectations of production quality. Consumer expectations are considered as the resource component of enterprise marketing potential.

  19. Determining factors affecting tourism demand for Malaysia using ARDL modeling: A case of Europe countries

    Science.gov (United States)

    Borhan, Nurbaizura; Arsad, Zainudin

    2016-10-01

    Tourism industry is the second largest foreign exchange earner after manufacturing in Malaysia. With regards to the importance of tourism industry in Malaysia, any factors that influence tourism demand should be considered cautiously by the government and tourism authorities in order to attract more international tourists in the near future. The purpose of this study is to investigate the dynamic long-run and short-run relationship between the number of international tourist arrivals from six European countries and four selected economic variables. The economic variables used in this study are exchange rate, gross domestic product, relative price and substitute relative price. This study also examines the impact of the European Sovereign crisis on the number of arrivals from the selected European countries to Malaysia. The data covers the period from quarter 1 (Q1) of 1999 to quarter 3 (Q3) of 2014 and employs the autoregressive distributed lag (ARDL) bounds testing approach proposed by Pesaran et al. (2001). The results of unit root test show a mixture of integrated at level and order one, I(0) and I(1). The results show that there exist long-run cointegration between the number of international tourist arrivals and exchange rate, level of income, tourism price and substitute tourism price for all countries. Generally, the results show that level of income is in line with the economic theory and Thailand is a competing destination for the tourism industry in Malaysia. Surprisingly, relative price is found to have positive impact on the number of arrivals to Malaysia and this suggests that an increase in the price level in Malaysia is unexpectedly increase the number of international tourist arrivals to Malaysia. Therefore the Malaysian government and tourism authorities should continue the efforts to withstand the growth of the tourism industry.

  20. SCHOOL MILK DEMAND – INTERACTION BETWEEN POLICY AND OTHER FACTORS: SOME PRELIMINARY FINDINGS OF A REGIONAL PROJECT

    OpenAIRE

    Christoph, Inken B.; Peter, Guenter; Rothe, Andrea; Salamon, Petra; Weber, Sascha A.; Weible, Daniela

    2010-01-01

    Given the recent steadily declining consumption of school milk in Germany, a research project was set up by the German Federal Ministry of Food, Agriculture and Consumer Protection, in affiliation with other institutions, to retrieve quantifiable information on the different influencing factors and to provide approaches for improving the school milk demand. Main objectives are to evaluate impacts of factors like price, attitudes and habits (especially consumption habits), social background, g...

  1. 卷烟销售异常管理联动机制的影响因素分析%Influencing Factors of Cigarette Exception Sale Linkage Mechanism

    Institute of Scientific and Technical Information of China (English)

    邓基刚

    2013-01-01

    本文通过构建卷烟销售异常联动管理机制影响因素的结构方程模型,以某市烟草公司为实证研究对象,并展开问卷调查获取数据,运用AMOS软件对该模型进行验证性因子分析,获得关键影响因素。基于实证研究结果,提出提升卷烟销售异常联动管理机制效率的对策。%Taking a tobacco company as the object of study, the paper builds the structural equation expression of influencing factors of cigarette exception sale linkage mechanism, and develops the questionnaire survey to get the data; it makes confirmatory factor analysis by using AMOS software and gets the key influencing factor. Based on the empirical research results, it puts forward the strategies of improving the efficiency of cigarette exception sale linkage mechanism.

  2. Job demands and job strain as risk factors for employee wellbeing in elderly care: an instrumental-variables analysis.

    Science.gov (United States)

    Elovainio, Marko; Heponiemi, Tarja; Kuusio, Hannamaria; Jokela, Markus; Aalto, Anna-Mari; Pekkarinen, Laura; Noro, Anja; Finne-Soveri, Harriet; Kivimäki, Mika; Sinervo, Timo

    2015-02-01

    The association between psychosocial work environment and employee wellbeing has repeatedly been shown. However, as environmental evaluations have typically been self-reported, the observed associations may be attributable to reporting bias. Applying instrumental-variable regression, we used staffing level (the ratio of staff to residents) as an unconfounded instrument for self-reported job demands and job strain to predict various indicators of wellbeing (perceived stress, psychological distress and sleeping problems) among 1525 registered nurses, practical nurses and nursing assistants working in elderly care wards. In ordinary regression, higher self-reported job demands and job strain were associated with increased risk of perceived stress, psychological distress and sleeping problems. The effect estimates for the associations of these psychosocial factors with perceived stress and psychological distress were greater, but less precisely estimated, in an instrumental-variables analysis which took into account only the variation in self-reported job demands and job strain that was explained by staffing level. No association between psychosocial factors and sleeping problems was observed with the instrumental-variable analysis. These results support a causal interpretation of high self-reported job demands and job strain being risk factors for employee wellbeing. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  3. Education Demand of New Generation Minority Migrant Workers in Kunming City and Survey of its Influence Factors

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Based on the questionnaire survey for 431 new generation minority migrant workers in Kunming City,we carried out empirical research on education demands of these migrant workers and its influence factors.Survey results show that their education demands have significant features in learning purposes,contents,expenses,willingness,and manners,which are subject to subjective mentality,economic income,social relation network,as well as shortage in social supply of education and training.Therefore,apart from solving training problem of new generation minority migrant workers,government should also highly value their demands of training and arouse their enthusiasm for participation in training in accordance with cultural and psychological characteristics and living environment of these migrant workers.

  4. Study of the Factors Influencing Entrepreneurial Farmers’ Formal Financial Credit Demand and Credit Constraints in Sichuan and Chongqing

    Institute of Scientific and Technical Information of China (English)

    Yingliang; ZHANG; Jianfeng; ZHANG; Guangying; LIU

    2015-01-01

    Based on a survey of 939 farmers in Sichuan and Chongqing,this paper analyzes the influencing factors of entrepreneurial farmers’ formal financial credit demands and credit constraints with Probit model. It is found that entrepreneurial farmers have strong demand for formal financial credit,which is mainly production investment demand,but the formal financial credit constraint is obvious. Family size,cognition of loan procedures and conditions have a positive effect on entrepreneurial farmers’ formal financial demand,while family per capita income,the distance between family location and the nearest formal financial organization,have negative influence. The relationship between householder’age and entrepreneurial farmers’ successful formal loan presents inverted U shape,and educational level presents a negative correlation with successful loan. Compared with the traditional scale agricultural business,farmers engaged in other entrepreneurial businesses would get loan from formal financial institutions more difficultly. Understanding level of the loan procedures and conditions has a positive effect on successful loan. Compared with entrepreneurial farmers without employment,employed farmers are more likely to get loans. Statistically,householder’ age and educational level,entrepreneurial business choices do not have significant effect on entrepreneurial households’ formal financial credit demands. Family size,family per capital income,the distance between family location and the nearest formal financial organization,and the size of loan do not have significant influence on entrepreneurial households’ successful loan. To get rid of formal financial credit constraints,we must implement the incremental reform of financial institutions,promote the formal finance of the villages and towns which can adapt to the farmers’ financial demand,and create a good financial environment. Meanwhile,it is necessary to give impetus to innovation of financial management

  5. The importance of genetic and shared environmental factors for the associations between job demands, control, support and burnout.

    Directory of Open Access Journals (Sweden)

    Victoria Blom

    Full Text Available Within occupational health research, one of the most influential models is the Job Demands-Control-Support model. Numerous studies have applied the model to different domains, with both physical and psychological health outcomes, such as burnout. The twin design provides a unique and powerful research methodology for examining the effects of environmental risk factors on burnout while taking familial factors (genetic and shared environment into account. The aim of the present study was to investigate the impact of familial factors on the associations of burnout with job demands, control and support. A total of 14,516 individuals from the Swedish Twin Registry, who were born between 1959 and 1986, and who participated in the Study of Twin Adults: Genes and Environment (STAGE by responding to a web-based questionnaire in 2005, were included in the analyses. Of these, there were 5108 individuals in complete same-sex twin pairs. Co-twin control analyses were performed using linear mixed modeling, comparing between-pairs effects and within-pair effects, stratified also by zygosity and sex. The results indicate that familial factors are of importance in the association between support and burnout in both women and men, but not between job demands and burnout. There are also tendencies towards familial factors being involved in the association between control and burnout in men. These results offer increased understanding of the mechanisms involved in the associations between work stress and burnout.

  6. Categorical analysis of factors affecting needs and demands for removable dentures among Alexandria Dental Research Center clientele.

    Science.gov (United States)

    Zeid, W M; Mohamed, M H; Mahdy, N H; El-Tabakh, S M

    1999-01-01

    An accurate assessment of dental needs is important to public health planners. With this information, it is possible to assess future treatment needs and demands for services including those for removable dentures. The present work aimed to estimate the magnitude and types of needs, and demands for partial or complete removable dentures, to study some factors that may affect the identified needs and demands for removable dentures, in addition to studying the factors that may affect satisfaction with the dentures. The present study was conducted in "Alexandria Dental Research Center". Data were collected by means of interview questionnaire, followed by dental examination of all patients attending the center for the sake of removable dental restorations for a period of 6 months. A further follow up over a period of three months was undertaken to the 330 cases recorded. About one third of the cases demanded partial and/or complete dentures and were above 60 years old. The first purpose for construction of new dentures was mastication, followed by cosmetics. Only one quarter of cases decided to have delayed immediate dentures. Diabetics and those having chronic diseases showed more demand for complete dentures. The most discriminating variable between the demand for different dentures was the missing in the lower anterior teeth followed by missing in the upper both anterior and posterior and then missing in the upper anterior teeth. Satisfaction score increased with advance of age, among males, among those for complete dentures, and those who had had previous dentures. Stepwise logistic regression revealed that the best predictor for overall satisfaction was the history of having previous dentures. Results of the present study, suggest that early screening and treatment of diabetic patients, gathering detailed information by means of a questionnaire before new dentures fabrication may be an important tool for the dentist in predicting and consequently enhancing patient

  7. How Sensitive is the Demand for Primary Education to Changes in Economic Factors

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt

    2001-01-01

    During the recession in the seventies and the eighties in LDCs in general and in Zambia in specific, private costs of schooling have increased and school quality has deteriorated. Combined with poverty, these changes may have damaged the demand for primary education. This observation motivates a ...

  8. Factors Influencing Compensation Demanded for Environmental Impacts Generated by Different Economic Activities

    Directory of Open Access Journals (Sweden)

    Virna Vaneza Gutiérrez

    2015-07-01

    Full Text Available This work advances the understanding of compensation demanded for environmental impacts on atmosphere, lakes and rivers, soil, and ocean generated by mining, urban, fishing and agriculture activities. Our aims are to determine whether compensation demanded depends on the standard variables used in the field of risk perception (as perceived risk, public acceptability and trust in regulating authorities, and to explore whether these relationships depend on the environment affected and on the economic activity generating the impacts. General Linear Models were used to analyze survey responses from 427 citizens of Santiago, Chile. Results showed that compensation demanded depends on perceived risk, acceptability, and on the economic activity, but not on the environment affected. Acceptability depends on trust in authorities, on perceived risk and on the economic activity. Perceived risk depends on trust, the economic activity and the environment affected. Overall, environmental impacts from the mining industry are perceived as riskier, less acceptable, and have a higher compensation demanded than those generated by the other sectors. These results suggest that to achieve sustainable development, regulations should consider not only environmental impacts but also the economic activity originating them.

  9. Demand for long acting and permanent contraceptive methods and associated factors among family planning service users, Batu town, Central Ethiopia.

    Science.gov (United States)

    Haile, Anley; Fantahun, Mesganaw

    2012-01-01

    Evidence suggests a high unsatisfied demand for long acting and permanent contraceptive methods in sub-Saharan Africa. However, there is limited knowledge on demand for long acting and permanent contraceptive methods and associated factors in Ethiopia. The objective of this study was to assess demand for long acting and permanent contraceptive methods and associated factors among women of age group 18-49 years in Batu town, East Shoa Zone, Ethiopia. A facility based cross-sectional survey was conducted in six service delivery points from March to April 2009 on 398 women of age 18-49 years old. Thirteen (3%) were using long acting and permanent contraceptive methods and 89 (22.4%) wanted no more child in the future making the total demand of long acting and permanent contraceptive methods 24.4%. Older age group, multiparty, that the provider asked about reproductive intention, and the provider explained side effects of method selected were significantly associated with using LA and MPs (P contraceptive methods indicating that multi-dimensional measures are needed to improve the use of long acting and permanent contraceptive methods.

  10. Supply- and Demand-Side Factors Influencing Utilization of Infant and Young Child Feeding Counselling Services in Viet Nam.

    Science.gov (United States)

    Nguyen, Phuong H; Kim, Sunny S; Nguyen, Tuan T; Tran, Lan M; Hajeebhoy, Nemat; Frongillo, Edward A; Ruel, Marie T; Rawat, Rahul; Menon, Purnima

    2016-01-01

    Adequate utilization of services is critical to maximize the impact of counselling on infant and young child feeding (IYCF), but little is known about factors affecting utilization. Our study examined supply- and demand-side factors associated with the utilization of IYCF counselling services in Viet Nam. We used survey data from mothers with children Higher maternal education was associated with higher utilization both for one-time and repeated use. Being a farmer, belonging to an ethnic minority, and having a wasted child were associated with greater likelihood of achieving the minimum recommended number of visits, whereas child stunting or illness were not. Distance to health center was a barrier to repeated visits. Among supply-side factors, good counselling skills (PR: 1.3-1.8) was the most important factor associated with any service use, whereas longer employment duration and greater work pressure of health center staff were associated with lower utilization. Population attributable risk estimations showed that an additional 25% of the population would have achieved the minimum number of visits if exposed to three demand-generation strategies, and further increased to 49% if the health staff had good counseling skills and low work pressure. Our study provides evidence that demand-generation strategies are essential to increase utilization of facility-based IYCF counselling services in Viet Nam, and may be relevant for increasing and sustaining use of nutrition services in similar contexts.

  11. How Sensitive is the Demand for Primary Education to Changes in Economic Factors

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt

    2001-01-01

    During the recession in the seventies and the eighties in LDCs in general and in Zambia in specific, private costs of schooling have increased and school quality has deteriorated. Combined with poverty, these changes may have damaged the demand for primary education. This observation motivates...... a study of the relationship between economic variables and the demand for primary education. A binary choice model for the school enrollment decision is estimated, and the relevance of economic incentives as concerns the decision to enroll in school is tested directly. Economic incentives to enroll...... in school are reflected in household income, educational expenses and quality indicators, and the results show that they all affect school enrollment as would be expected, even though the magnitudes of the effects are relatively moderate. Udgivelsesdato: JUL...

  12. An Empirical Estimation of the Factors Affecting Demand and Supply of Poultry Meat

    Directory of Open Access Journals (Sweden)

    Abdul Ghafoor*, Hammad Badar, Maqsood Hussain and Naeem Tariq

    2010-07-01

    Full Text Available Poultry sector is one of the most important segments in agriculture sector of Pakistan. Despite growth in poultry sector, many new challenges including bird flu, fluctuating prices and higher cost of production have affected pace of development of this sector. The present study was conducted to evaluate the impact of various variables affecting supply of poultry birds and demand of poultry meat in Faisalabad, Pakistan. Cross sectional data were collected from 40 poultry farmers and 40 consumers selected randomly from Faisalabad city. Simple linear form of regression analysis was employed to estimate effect of major variables. Sale price of poultry birds, average cost of production and experience of the poultry farmers significantly (P<0.05 affected supply of poultry birds, whereas education of farmers and distance from markets had non-significant effect. Income of the consumers, family size and retail price of poultry meat were found significant variables, whereas age and education of consumers were non-significant variables affecting demand. A qualitative variable was used to capture effect of bird flu on supply and demand of poultry meat, which was found significant in both models. This finding establishes the serious implications of bird flu epidemic for poultry industry in Pakistan.

  13. A Budget Impact Model of Hemophilia Bypassing Agent Prophylaxis Relative to Recombinant Factor VIIa On-Demand.

    Science.gov (United States)

    Mehta, Darshan A; Oladapo, Abiola O; Epstein, Joshua D; Novack, Aaron R; Neufeld, Ellis J; Hay, Joel W

    2016-02-01

    Hemophilia patients use factor-clotting concentrates (factor VIII for hemophilia A and factor IX for hemophilia B) for improved blood clotting. These products are used to prevent or stop bleeding episodes. However, some hemophilia patients develop inhibitors (i.e., the patient's immune system develops antibodies against these factor concentrates). Hence, these patients do not respond well to the factor concentrates. A majority of hemophilia patients with inhibitors are managed on-demand with the following bypassing agents: recombinant factor VIIa (rFVIIa) and activated prothrombin complex concentrate (aPCC). The recently published U.S. registries Dosing Observational Study in Hemophilia (DOSE) and Hemostasis and Thrombosis Research Society (HTRS) reported higher rFVIIa on-demand use for bleed management than previously described. To estimate aPCC and rFVIIa prophylaxis costs relative to rFVIIa on-demand treatment cost based on rFVIIa doses reported in U.S. registries. A literature-based cost model was developed assuming a base case on-demand annual bleed rate (ABR) of 28.7 per inhibitor patient, which was taken from a randomized phase 3 clinical trial. The doses for rFVIIa on-demand were taken from the median dose per bleed reported by the DOSE and HTRS registries. Model inputs for aPCC and rFVIIa prophylaxis (i.e., dosing and efficacy) were derived from respective randomized clinical trials. Cost analysis was from the U.S. payer perspective, and only direct drug costs were considered. The drug cost was based on the Medicare Part B 2014 average sale price (ASP). Two-way sensitivity and threshold analyses were performed by simultaneously varying on-demand ABR, prophylaxis efficacy, and unit drug cost. In addition to studying relative costs associated with on-demand and prophylaxis treatments, relative cost per bleeding episode avoided were also calculated for aPCC and rFVIIa prophylaxis treatments. The prophylaxis efficacy reported in the trials were used to

  14. Factors Influencing Demand for a Producer-Owned Beef Retail Outlet

    OpenAIRE

    Lusk, Jayson L.; Cevallos, Edgar

    2004-01-01

    As the farm-to-retail price spread continues to grow, come cattle producers a beginning to consider integrating into the retail sector. Such a venture would require large investments in capital with uncertain return. This study seeks to determine the potential success of a stand-alone retail outlet selling “all natural†beef in an affluent area of Jackson, MS. Using choice-based conjoint analysis, demand for the new retail outlet is modeled as a function of the beef price at the store, dis...

  15. An analysis of the factors influencing demand-side management activity in the electric utility industry

    Science.gov (United States)

    Bock, Mark Joseph

    Demand-side management (DSM), defined as the "planning, implementation, and monitoring of utility activities designed to encourage consumers to modify their pattern of electricity usage, including the timing and level of electricity demand," is a relatively new concept in the U.S. electric power industry. Nevertheless, in twenty years since it was first introduced, utility expenditures on DSM programs, as well as the number of such programs, have grown rapidly. At first glance, it may seem peculiar that a firm would actively attempt to reduce demand for its primary product. There are two primary explanations as to why a utility might pursue DSM: regulatory mandate, and self-interest. The purpose of this dissertation is to determine the impact these influences have on the amount of DSM undertaken by utilities. This research is important for two reasons. First, it provides insight into whether DSM will continue to exist as competition becomes more prevalent in the industry. Secondly, it is important because no one has taken a comprehensive look at firm-level DSM activity on an industry-wide basis. The primary data set used in this dissertation is the U.S. Department of Energy's Annual Electric Utility Report, Form EIA-861, which represents the most comprehensive data set available for analyzing DSM activity in the U.S. There are four measures of DSM activity in this data set: (1) utility expenditures on DSM programs; (2) energy savings by DSM program participants; and (3) the actual and (4) the potential reductions in peak load resulting from utility DSM measures. Each is used as the dependent variable in an econometric analysis where independent variables include various utility characteristics, regulatory characteristics, and service territory and customer characteristics. In general, the results from the econometric analysis suggest that in 1993, DSM activity was primarily the result of regulatory pressure. All of the evidence suggests that if DSM continues to

  16. VT Wildlife Linkage Habitat

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Wildlife Linkage Habitat Analysis uses landscape scale data to identify or predict the location of potentially significant wildlife linkage...

  17. Factors influencing car users propensity to shift to other modes and their impacts on demand for airport parking facilities

    Directory of Open Access Journals (Sweden)

    Konstantinos Panou

    2014-01-01

    Full Text Available Purpose: The aim of this paper is to analyse the factors influencing car user behaviour and examine the possible impacts of public transit improvements on the demand for airport long-term parking facilities. The case of the Athens International Airport (AIA is considered for the analysis. Design/methodology/approach: The followed approach comprises three steps: First the related literature is reviewed (section 2 and the methodological approach is presented (section 3. Then data collection is carried out through a survey questionnaire comprising a Revealed Preferences (RP and a Stated Preference (SP part (section 4. The compiled data is processed using factor analysis (section 5. Finally, the results are assessed leading to the drawing of final conclusions (section 6. Findings: The results of the analysis enable: (a to determine different user groups with different demand elasticities and likelihoods to shift to public transport, and (b to conclude from the quantitative representation of the different user groups the real impact on the car parking demand. Research limitations: The analysis gives no consideration to the mix of measures that can possibly increase competitiveness of parking services such as real-time information about availability of parking space to users; online booking and discount rates for early birds, etc. Originality/value: The paper includes original work based on primary data from a field survey, similar of which has not been published for the AIA. The results are important for airport authorities to keep a balance between parking demand and supply by formulating the right marketing policies.

  18. Modelling of INTER-Linkages Between LAND Cover Pattern and Socio-Economic Factors in the Idemili River Basin of South Eastern Nigeria

    Science.gov (United States)

    Maduekwe, N. I.; Adesina, F. A.

    2014-12-01

    This study explores the inter-relationships between socio-economic factors and land cover pattern in the Idemili River Basin of South Eastern Nigeria. It is based on the concept of coupled human environment systems and focuses on the modelling of community scale relationships between critical land cover parameter and socio-demographic, economic and cultural factors in the basin. The modelling was implemented with pixel level NDVI indicators of vegetation cover density developed from NigeriaSat image with 32m resolution linked to eight indicators of socio-economic factors developed from a household survey of the basin. NDVI and socio-economic data were matched for 25 sampled localities in the basin and their relationships modelled with correlation, regression and Principal Component Analysis statistics. NDVI based image analysis showed a high level of human impact on vegetation. The Model output shows that bivariate relationships between vegetation cover dynamics and socio-demographic variables were the most significant, with R Square values > 0.60 for linear and non linear models. Vegetation cover density has high inverse correlations with population, urbanization levels and number of households in localities. Population/urbanization status of localities was also the most significant Principal Component or underlying dimension linked to spatial dynamics of vegetation cover in the basin accounting for 50% of factor variations. Relationships between vegetation cover densities and economic factors (occupational and household energy patterns) and socio-cultural factors (environmental knowledge, values and governance) were weaker and less significant. The study captured the linkages between landcover- represented by vegetation cover- and socio-economic parameters. It demonstrates that socio-economic factors are major drivers of change in the basin. Key Words: Socio-economic factors, Vegetation Cover, NDVI, Socio-ecological Systems, State Variables, South Eastern Nigeria

  19. Supply- and Demand-Side Factors Influencing Utilization of Infant and Young Child Feeding Counselling Services in Viet Nam.

    Directory of Open Access Journals (Sweden)

    Phuong H Nguyen

    Full Text Available Adequate utilization of services is critical to maximize the impact of counselling on infant and young child feeding (IYCF, but little is known about factors affecting utilization. Our study examined supply- and demand-side factors associated with the utilization of IYCF counselling services in Viet Nam. We used survey data from mothers with children <2y (n = 1,008 and health staff (n = 60 from the evaluation of a program that embedded IYCF counseling into the existing government health system. The frequency of never users, one-time users, repeat users, and achievers of the recommended minimum number of visits at health facilities were 45.1%, 13.0%, 28.4% and 13.5%, respectively. Poisson regression showed that demand-generation strategies, especially invitation cards, were the key factors determining one-time use (Prevalence ratio, PR 3.0, 95% CI: 2.2-4.2, repeated use (PR 3.2, 95% CI: 2.4-4.2, and achievement of minimum visits (PR 5.5, 95% CI: 3.6-8.4. Higher maternal education was associated with higher utilization both for one-time and repeated use. Being a farmer, belonging to an ethnic minority, and having a wasted child were associated with greater likelihood of achieving the minimum recommended number of visits, whereas child stunting or illness were not. Distance to health center was a barrier to repeated visits. Among supply-side factors, good counselling skills (PR: 1.3-1.8 was the most important factor associated with any service use, whereas longer employment duration and greater work pressure of health center staff were associated with lower utilization. Population attributable risk estimations showed that an additional 25% of the population would have achieved the minimum number of visits if exposed to three demand-generation strategies, and further increased to 49% if the health staff had good counseling skills and low work pressure. Our study provides evidence that demand-generation strategies are essential to increase

  20. INFLUENCE OF SUPPLY AND DEMAND FACTORS AT THE DEVELOPMENT OF ENVIRONMENTALLY RESPONSIBLE HOUSING AND UTILITIES SECTOR IN THE RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    Natalia B. Safronova

    2016-11-01

    Full Text Available Empirical marketing regional research on supply and demand factors of housing and communal services (HCS revealed determinants of customer loyalty and satisfaction with the service level and factors influencing on willingness to purchase additional services. Specific features of housing and utilities sector (HUS as a social significant industry determine requirements to models reflecting reciprocal influence of indices of satisfaction, loyalty and economic indices of operation. The article presents definition of requirements along with development of techniques for modeling influence of satisfaction and loyalty on consumer behaviour of clients. The authors demonstrate trustworthy statistical results of correlative interrelationship of different factors. There have been designed regression models for taking management solutions by executives of management company housing and communal services at the development environmental responsibility. The causes that lead and hamper development of socially oriented services in different regions of the Russian Federation have been identified.

  1. Inclusion of climatic and touristic factors in the analysis and modelling of the municipal water demand in a Mediterranean region

    Science.gov (United States)

    Toth, Elena; Bragalli, Cristiana; Neri, Mattia

    2017-04-01

    In Mediterranean regions, inherently affected by water scarcity conditions, the gap between water availability and demand may further increase in the near future due to both climatic and anthropogenic drivers. In particular, the high degree of urbanization and the concentration of population and activities in coastal areas is often severely impacting the water availability also for the residential sector. It is therefore crucial analysing the importance of both climatic and touristic factors as drivers for the water demand in such areas, to better understand and model the expected consumption in order to improve the water management policies and practices. The study presents an analysis referred to a large number of municipalities, covering almost the whole Romagna region, in Northern Italy, representing one of the most economically developed areas in Europe and characterized by an extremely profitable tourist industry, especially in the coastal cities. For this region it is therefore extremely important to assess the significance of the drivers that may influence the demand in the different periods of the year, that is climatic factors (rainfall depths and occurrence, temperature averages and extremes), but also the presence of tourists, in both official tourist accommodation structures and in holidays homes (and the latter are very difficult to estimate). Analyses on the Italian water industry at seasonal or monthly time scale has been so far, extremely limited in the literature by the scarce availability of data on the water demands, that are made public only as annual volumes. All the study municipalities are supplied by the same water company, who provided monthly consumption volumes data at the main inlet points of the entire distribution network for a period of 7 years (2009-2015). For the same period, precipitation and temperature data have been collected and summarised in indexes representing monthly averages, days of occurrence and over threshold values

  2. Employee retention and integrated disability management practices as demand side factors.

    Science.gov (United States)

    Habeck, Rochelle; Hunt, Allan; Rachel, Colleen Head; Kregel, John; Chan, Fong

    2010-12-01

    Demand-side employment research on company policies and practices related to retention and absence and disability management (ADM) can contribute to our understanding of employment issues related to people with disabilities from the employers' perspective. To examine company ADM and retention practices and their effectiveness, as well as how these company policies and practices might influence hiring of people with disabilities. Disability Management Employer Coalition employer members (N = 650) were surveyed by internet and the survey data were analyzed using descriptive statistics, correlation, and multiple regression. Ninety-five participants responded to the survey resulting in a response rate of 14%. Retention practice was found to be associated with retention effectiveness (r = .39, P employees at every level, seeking the ideas and involvement of employees, and assuring they know how their work and performance support the mission. ADM practice was related to improving health and managing health conditions (r = .26, P employee-oriented culture (r = .23), safety/risk prevention (r = .21), and very early intervention (r = .21) correlated with delaying/preventing employment exits related to health impairment. Retention practice, ADM practice, retention effectiveness, ADM effectiveness and disability attitudes comprised a model to predict the hiring of people with disabilities. The six-predictor model was significant, F(6, 86) = 13.54, P employees who develop potentially disabling conditions; but they are not directly connected to hiring people with disabilities. These appear to be two different policy and practice issues within most companies.

  3. Important Factors for Early Market Microgrids: Demand Response and Plug-in Electric Vehicle Charging

    Science.gov (United States)

    White, David Masaki

    Microgrids are evolving concepts that are growing in interest due to their potential reliability, economic and environmental benefits. As with any new concept, there are many unresolved issues with regards to planning and operation. In particular, demand response (DR) and plug-in electric vehicle (PEV) charging are viewed as two key components of the future grid and both will likely be active technologies in the microgrid market. However, a better understanding of the economics associated with DR, the impact DR can have on the sizing of distributed energy resource (DER) systems and how to accommodate and price PEV charging is necessary to advance microgrid technologies. This work characterizes building based DR for a model microgrid, calculates the DER systems for a model microgrid under DR through a minimization of total cost, and determines pricing methods for a PEV charging station integrated with an individual building on the model microgrid. It is shown that DR systems which consist only of HVAC fan reductions provide potential economic benefits to the microgrid through participation in utility DR programs. Additionally, peak shaving DR reduces the size of power generators, however increasing DR capacity does not necessarily lead to further reductions in size. As it currently stands for a microgrid that is an early adopter of PEV charging, current installation costs of PEV charging equipment lead to a system that is not competitive with established commercial charging networks or to gasoline prices for plug-in hybrid electric vehicles (PHEV).

  4. Fine mapping quantitative trait loci under selective phenotyping strategies based on linkage and linkage disequilibrium criteria

    DEFF Research Database (Denmark)

    Ansari-Mahyari, S; Berg, P; Lund, M S

    2009-01-01

    In fine mapping of a large-scale experimental population where collection of phenotypes are very expensive, difficult to record or time-demanding, selective phenotyping could be used to phenotype the most informative individuals. Linkage analyses based sampling criteria (LAC) and linkage...... disequilibrium-based sampling criteria (LDC) for selecting individuals to phenotype are compared to random phenotyping in a quantitative trait loci (QTL) verification experiment using stochastic simulation. Several strategies based on LAC and LDC for selecting the most informative 30%, 40% or 50% of individuals...... for phenotyping to extract maximum power and precision in a QTL fine mapping experiment were developed and assessed. Linkage analyses for the mapping was performed for individuals sampled on LAC within families and combined linkage disequilibrium and linkage analyses was performed for individuals sampled across...

  5. Calculating load factors for the transatlantic airline market using supply and demand data: a note on the identification of gaps in the available airline statistics

    NARCIS (Netherlands)

    Devriendt, L.; Burghouwt, G.; Derudder, B.; de Wit, J.; Witlox, F.

    2009-01-01

    This paper takes a critical view of the verification of load factors for the direct transatlantic airline market by combining supply and demand-data. The supply-related data originate from the Official Airline Guide, a well-known data source that contains information on scheduled flights. The demand

  6. Linkage of ICF-CY codes with environmental factors in studies of developmental outcomes of infants and toddlers with or at risk for motor delays.

    Science.gov (United States)

    Hwang, Ai-Wen; Liao, Hua-Fang; Granlund, Mats; Simeonsson, Rune J; Kang, Lin-Ju; Pan, Yi-Ling

    2014-01-01

    Environmental variables have been explored in studies of the development of young children with motor delays. Linking environmental variables to the International Classification of Functioning, Disability and Health - Children and Youth (ICF-CY), environmental factors (EFs) categories can provide a common language for documenting their contribution to developmental outcomes. This review of studies aimed to (1) link EFs for developmental outcomes in infants with or at risk for motor delays to ICF-CY categories and (2) synthesize the influences of EFs (with ICF-CY linkage) on developmental outcomes. A systematic literature search was performed of multiple databases. After applying selection criteria, environmental variables in 28 articles were linked to ICF-CY categories and underwent qualitative synthesis. Results indicated that physical environmental variables could be linked successfully to ICF-CY EFs categories, but not social environmental variables. Multiple environmental variables were associated with motor and other developmental outcomes. Difficulties in linking social factors to ICF-CY categories indicate that additional EFs codes may need to be considered in the ICF-CY revision processes. The review provides empirical data on relationships between EFs and developmental outcomes in children with or at risk for motor delay.

  7. Herd-level risk factors for antimicrobial demanding gastrointestinal diseases in Danish herds with finisher pigs

    DEFF Research Database (Denmark)

    Hybschmann, G. K.; Ersbøll, A.K.; Vigre, Håkan

    2011-01-01

    quarter per herd. Three potential herd-level risk factors were evaluated: herd size (number of finishers delivered for slaughter); herd health status (herds in the Specific Pathogen Free (SPF) System, conventional herds); and herd type (herds including only finishers, integrated herds). Data were analyzed...... using general linear mixed models with repeated measurements. Smaller herds had a larger AMU per finisher than larger herds. Integrated herds had lower AMU as compared with herds with only finishers. Herds within the SPF System had a larger decrease in AMU with increasing herd size compared...

  8. The role of brain-derived neurotrophic factor (BDNF in comorbid depression: possible linkage with steroid hormones, cytokines, and nutrition

    Directory of Open Access Journals (Sweden)

    Tadahiro eNumakawa

    2014-09-01

    Full Text Available Increasing evidence demonstrates a connection between growth factor function (including brain-derived neurotrophic factor, BDNF, glucocorticoid levels (one of the steroid hormones, and the pathophysiology of depressive disorders. Because both BDNF and glucocorticoids regulate synaptic function in the central nervous system, their functional interaction is of major concern. Interestingly, alterations in levels of estrogen, another steroid hormone, may play a role in depressive-like behavior in postpartum females with fluctuations of BDNF-related molecules in the brain. BDNF and cytokines, which are protein regulators of inflammation, stimulate multiple intracellular signaling cascades involved in neuropsychiatric illness. Pro-inflammatory cytokines may increase vulnerability to depressive symptoms, such as the increased risk observed in patients with cancer and/or autoimmune diseases. In this review, we discuss the possible relationship between inflammation and depression, in addition to the crosstalk among cytokines, BDNF and steroids. Further, since nutritional status has been shown to affect critical pathways involved in depression through both BDNF function and the monoamine system, we also review current evidence surrounding diet and supplementation (e.g., flavonoids on BDNF-mediated brain functions.

  9. Atmospheric evaporative demand observations, estimates and driving factors in Spain (1961-2011)

    KAUST Repository

    Azorin-Molina, Cesar

    2015-04-01

    We analyzed the spatio-temporal evolution of evaporation observations from Piché atmometers (1961-2011; 56 stations) and Pan evaporimeters (1984-2011; 21 stations) across Spain, and compared both measurements with evaporation estimates obtained by four physical models: i.e., Food and Agricultural Organization-56 Penman-Monteith, Food and Agricultural Organization-Pan, PenPan and Penman, based on climate data. In this study we observed a positive and statistically significant correlation between Piché and Pan evaporation measurements during the common period (1984-2011; 19 stations), mainly in summer. When evaporation observations and estimates were compared, we detected positive and statistically significant correlations with the four methods, except for winter. Among the four physical models, the FAO-Pan showed the best fitting to both Piché and Pan evaporation measurements; the PenPan model overestimated evaporation rates; and the FAO-Penman-Monteith and Penman methods underestimated evaporation observations. We also observed a better spatial agreement between Pan evaporation and estimates than that obtained by Piché measurements. Annual and seasonal trends of evaporation estimates show a statistically significant increase for 1961-2011, which do not agree with long-term Piché evaporation trends; e.g. a discontinuity was found around the 1980s. Radiative and aerodynamic driving factors suggest that this discontinuity, and the observed evaporation trends across Spain could be associated with the abrupt increase in air temperature observed during last few decades (i.e., global warming). Further investigations using available Piché evaporation observations for other regions are needed to better understand physical components influencing long-term trends of evaporation.

  10. Aspects of record linkage

    NARCIS (Netherlands)

    Schraagen, Marijn Paul

    2014-01-01

    This thesis is an exploration of the subject of historical record linkage. The general goal of historical record linkage is to discover relations between historical entities in a database, for any specific definition of relation, entity and database. Although this task originates from historical

  11. Subsidiary Linkage Patterns

    DEFF Research Database (Denmark)

    Andersson, Ulf; Perri, Alessandra; Nell, Phillip C.

    2012-01-01

    This paper investigates the pattern of subsidiaries' local vertical linkages under varying levels of competition and subsidiary capabilities. Contrary to most previous literature, we explicitly account for the double role of such linkages as conduits of learning prospects as well as potential...

  12. Drugs-Related Death Soon after Hospital-Discharge among Drug Treatment Clients in Scotland: Record Linkage, Validation, and Investigation of Risk-Factors.

    Directory of Open Access Journals (Sweden)

    Simon R White

    Full Text Available We validate that the 28 days after hospital-discharge are high-risk for drugs-related death (DRD among drug users in Scotland and investigate key risk-factors for DRDs soon after hospital-discharge. Using data from an anonymous linkage of hospitalisation and death records to the Scottish Drugs Misuse Database (SDMD, including over 98,000 individuals registered for drug treatment during 1 April 1996 to 31 March 2010 with 705,538 person-years, 173,107 hospital-stays, and 2,523 DRDs. Time-at-risk of DRD was categorised as: during hospitalization, within 28 days, 29-90 days, 91 days-1 year, >1 year since most recent hospital discharge versus 'never admitted'. Factors of interest were: having ever injected, misuse of alcohol, length of hospital-stay (0-1 versus 2+ days, and main discharge-diagnosis. We confirm SDMD clients' high DRD-rate soon after hospital-discharge in 2006-2010. DRD-rate in the 28 days after hospital-discharge did not vary by length of hospital-stay but was significantly higher for clients who had ever-injected versus otherwise. Three leading discharge-diagnoses accounted for only 150/290 DRDs in the 28 days after hospital-discharge, but ever-injectors for 222/290. Hospital-discharge remains a period of increased DRD-vulnerability in 2006-2010, as in 1996-2006, especially for those with a history of injecting.

  13. Energy Demand

    NARCIS (Netherlands)

    Stehfest, E. et al.

    2014-01-01

    Key policy issues – How will energy demand evolve particularly in emerging and medium- and low- income economies? – What is the mix of end-use energy carriers to meet future energy demand? – How can energy efficiency contribute to reducing the growth rate of energy demand and mitigate pressures on t

  14. Factors and models associated with the amount of hospital care services as demanded by hospitalized patients: a systematic review.

    Directory of Open Access Journals (Sweden)

    Catharina J van Oostveen

    Full Text Available BACKGROUND: Hospitals are constantly being challenged to provide high-quality care despite ageing populations, diminishing resources, and budgetary restraints. While the costs of care depend on the patients' needs, it is not clear which patient characteristics are associated with the demand for care and inherent costs. The aim of this study was to ascertain which patient-related characteristics or models can predict the need for medical and nursing care in general hospital settings. METHODS: We systematically searched MEDLINE, Embase, Business Source Premier and CINAHL. Pre-defined eligibility criteria were used to detect studies that explored patient characteristics and health status parameters associated to the use of hospital care services for hospitalized patients. Two reviewers independently assessed study relevance, quality with the STROBE instrument, and performed data analysis. RESULTS: From 2,168 potentially relevant articles, 17 met our eligibility criteria. These showed a large variety of factors associated with the use of hospital care services; models were found in only three studies. Age, gender, medical and nursing diagnoses, severity of illness, patient acuity, comorbidity, and complications were the characteristics found the most. Patient acuity and medical and nursing diagnoses were the most influencing characteristics. Models including medical or nursing diagnoses and patient acuity explain the variance in the use of hospital care services for at least 56.2%, and up to 78.7% when organizational factors were added. CONCLUSIONS: A larger variety of factors were found to be associated with the use of hospital care services. Models that explain the extent to which hospital care services are used should contain patient characteristics, including patient acuity, medical or nursing diagnoses, and organizational and staffing characteristics, e.g., hospital size, organization of care, and the size and skill mix of staff. This would

  15. Subsidiary Linkage Patterns

    DEFF Research Database (Denmark)

    Perri, Alessandra; Andersson, Ulf; Nell, Phillip C.;

    This paper investigates local vertical linkages of foreign subsidiaries and the dual role of such linkages as conduits for learning as well as potential channels for spillovers to competitors. On the basis of data from 97 subsidiaries, we analyze the quality of such linkages under varying levels...... of competition and subsidiary capabilities. Our theoretical development and the results from the analysis document a far more complex and dynamic relationship between levels of competition and MNCs’ local participation in knowledge intensive activities, i.e. learning and spillovers, than previous studies do. We...

  16. Linkage analysis in alcohol dependence.

    Science.gov (United States)

    Windemuth, C; Hahn, A; Strauch, K; Baur, M P; Wienker, T F

    1999-01-01

    Alcohol dependence often is a familial disorder and has a genetic component. Research in causative factors of alcoholism is coordinated by a multi-center program, COGA [The Collaborative Study on the Genetics of Alcoholism, Begleiter et al., 1995]. We analyzed a subset of the COGA family sample, 84 pedigrees of Caucasian ancestry comprising 745 persons, 339 of whom are affected according to DSM-III-R and Feighner criteria. Using parametric and nonparametric methods, evidence for linkage was found on chromosome 1 (near markers D1S532, D1S1588, and D1S534), as well as on chromosome 15 (near marker D15S642). Other regions of the genome showed suggestive evidence for contributing loci. Related findings are discussed in recent publications investigating linkage in humans [Reich et al., 1998] and mice [Melo et al., 1996].

  17. Analysis of the key factors of the change in the demand of electrical energy in Neuquén

    Directory of Open Access Journals (Sweden)

    Griselda Domeett

    2015-12-01

    Full Text Available The electrical energy is a basic input of high diffusion, derived from its capacity to satisfy all type of necessities. It shows that seasonal alterations in the consumptions are motivated by the level of economic activity, climatic changes and demographic dynamics. Since this is an essential good that cannot be stored, it determines the configuration, planning, operation and organization of the electrical energy systems. Its particular feature is forced to perform a multidimensional coverage: technological, economic, political, legal and environmental. The analysis of the factors that determine the levels and structures of the electric energy consumption it allows to identify the supplying problems, and the actions and policies that promote the sustainable usage of the service.Accordingly, the current work tries to make a preliminary analysis of these changes in the capital city of Neuquén, since the 90s until recent years. In order to do this, information from the Population Census, Provincial Registers, Household Surveys, Consumption and Invoicing sector, has been used.                                                                                          Keywords: Electrical energy, demand evolution key factors

  18. Demand for long acting contraceptive methods and associated factors among family planning service users, Northwest Ethiopia: a health facility based cross sectional study.

    Science.gov (United States)

    Yalew, Saleamlak Adbaru; Zeleke, Berihun Megabiaw; Teferra, Alemayehu Shimeka

    2015-02-04

    Demand for long acting contraceptive methods is one of the key factors for total fertility rate and reproductive health issues. Increased demand for these methods can decline fertility rate through spacing and limiting family size in turn improving maternal and family health and socioeconomic development of a country. The aim of this study was to assess demand for long acting contraceptives and associated factors among family planning users in Debre-Tabor Town, Northwest Ethiopia. Facility based cross-sectional study was conducted from July to August 2013. Data was collected on 487 current family planning users through face to face interview using structured questionnaire. Study participants were selected by systematic sampling method. Data were entered in to Epi Info and analyzed by using SPSS version 20. Bi-variable and multi-variable regression analyses were done to identify factors associated with demand for long acting contraceptive methods. Odds ratio with 95% CI was used to assess the association between the independent variables and demand for long acting family planning methods. The study showed that, demand for long acting contraceptives was 17%. Only 9.2% of the women were using long acting contraceptive methods (met need). About 7.8% of women were using short acting methods while they actually want to use long acting methods (unmet need). Demand for LACMs was positively associated 3 with being a daily labour (AOR = 3.87, 95% CI = [1.06, 14.20]), being a student (AOR = 2.64, 95% CI = [1.27, 5.47]), no future birth intensions (AOR = 2.17, 95% CI = [1.12, 4.23]), having five or more children (AOR = 1.67, 95% CI = [1.58, 4.83]), deciding together with husbands for using the methods (AOR = 2.73, 95% CI = [1.40, 5.32]) and often having discussion with husband (AOR = 3.89, 95% CI = [1.98, 7.65]). Clients treated poorly by the health care providers during taking the services was negatively associated with demand for LACMs (AOR = 0.42, 95% CI = [0.24, 0

  19. THE ACCURACY OF DEMAND FORECAST MODELS AS A CRITICAL FACTOR IN THE FINANCIAL PERFORMANCE OF THE FOOD INDUSTRY

    Directory of Open Access Journals (Sweden)

    Cássia Rita Pereira Da Veiga

    2010-11-01

    Full Text Available Every organization needs to balance their production capacities with demand. The role of demand forecasting is to assist in the organization's strategic planning; this process allows administrators to anticipate the future and plot an appropriate course of action. On its own, however, a system of demand forecasting is not enough. It is the quality of information obtained by this system which enables the organization to achieve better operational planning. In this context, this paper presents case study research to: (a define the quantitative model to forecast demand with greater accuracy; and (b to verify the influence of accuracy in demand forecasting on financial performance. This is an ex-post facto descriptive inquiry with a time series in which we made use of historical data from five groups of products over the period 2004–2008. The results suggest that if a company employs the ARIMA model for groups A, B, and E; the Holt model for group D; and the Winter model for group C, revenues will increase by approximately $1,600,000 annually. Key-words: Accuracy. Demand forecasting. Financial performance. 

  20. Calculating load factors for the transatlantic airline market using supply and demand data: a note on the identification of gaps in the available airline statistics

    NARCIS (Netherlands)

    Devriendt, L.; Burghouwt, G.; Derudder, B.; de Wit, J.; Witlox, F.

    2009-01-01

    This paper takes a critical view of the verification of load factors for the direct transatlantic airline market by combining supply and demand-data. The supply-related data originate from the Official Airline Guide, a well-known data source that contains information on scheduled flights. The

  1. Innovation and Demand

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    2007-01-01

    the demand-side of markets in the simplest possible way. This strategy has allowed a gradual increase in the sophistication of supply-side aspects of economic evolution, but the one-sided focus on supply is facing diminishing returns. Therefore, demand-side aspects of economic evolution have in recent years...... received increased attention. The present paper argues that the new emphasis on demand-side factors is quite crucial for a deepened understanding of economic evolution. The major reasons are the following: First, demand represents the core force of selection that gives direction to the evolutionary process....... Second, firms' innovative activities relate, directly or indirectly, to the structure of expected and actual demand. Third, the demand side represents the most obvious way of turning to the much-needed analysis of macro-evolutionary change of the economic system....

  2. Interactive Record Linkage

    Directory of Open Access Journals (Sweden)

    2000-12-01

    Full Text Available In order to carry out demographic analyses at individual and group levels, a manual method of linking individual event records from parish registers was developed in the late 1950s. In order to save time and to work with larger areas than small parishes, systems for automatic record linkage were developed a couple of decades later. A third method, an interactive record linkage, named Demolink, has been developed even more recently. The main new feature of the method is the possibility of linking from more than two historical sources simultaneously. This improves the process of sorting out which events belong to which individual life courses. This paper discusses how Demolink was used for record linkage in a large Norwegian parish for the period 1801-1878.

  3. Demand Uncertainty

    DEFF Research Database (Denmark)

    Nguyen, Daniel Xuyen

    This paper presents a model of trade that explains why firms wait to export and why many exporters fail. Firms face uncertain demands that are only realized after the firm enters the destination. The model retools the timing of uncertainty resolution found in productivity heterogeneity models...... in untested destinations. The option to forecast demands causes firms to delay exporting in order to gather more information about foreign demand. Third, since uncertainty is resolved after entry, many firms enter a destination and then exit after learning that they cannot profit. This prediction reconciles...

  4. Demand factors that influence financial inclusion in Mexico: analysis of the barriers based on the ENIF survey

    OpenAIRE

    Carmen Hoyo; Ximena Pena; David Tuesta

    2013-01-01

    In Mexico 62% of adults between the ages of 18 and 70 do not have formal savings or credit products, even though 97% of adults have access to them through different channels. The difference between the supply and the effective use of the financial system means the existence of demand barriers that have not been explored fully so far. Thanks to the interest of the Mexican government in measuring and evaluating financial inclusion from the point of view of supply and demand, the first National ...

  5. Demand forecasting

    OpenAIRE

    Gregor, Belčec

    2011-01-01

    Companies operate in an increasingly challenging environment that requires them to continuously improve all areas of the business process. Demand forecasting is one area in manufacturing companies where we can hope to gain great advantages. Improvements in forecasting can result in cost savings throughout the supply chain, improve the reliability of information and the quality of the service for our customers. In the company Danfoss Trata, d. o. o. we did not have a system for demand forecast...

  6. Exploring the condom gap: is supply or demand the limiting factor - condom access and use in an urban and a rural setting in Kilifi district, Kenya.

    Science.gov (United States)

    Papo, Jacqueline K; Bauni, Evasius K; Sanders, Eduard J; Brocklehurst, Peter; Jaffe, Harold W

    2011-01-14

    to explore the extent of the condom gap, investigating the relative roles of supply-side and demand-side factors in determining condom use. GPS mapping of condom outlets, and population-based survey. an urban and a rural site were selected within the Epidemiological and Demographic Surveillance Site in Kilifi district, Kenya. Potential condom outlets (n = 281) were mapped and surveyed, and questionnaires on condom access and use (n = 630) were administered to a random sample of men and women aged 15-49. Multivariate logistic regression was performed to assess the relative roles of supply-side and demand-side barriers on condom use. the median straight-line distance to free condoms was 18-fold higher in the rural versus urban site. Among sexually active respondents, 42% had ever used a condom, and 23% had used a condom over the past 12 months, with lower levels among rural versus urban respondents (P supply-side or demand-side barriers, compared with individuals experiencing both types of barriers. Despite low levels of usage and the presence of supply-side and demand-side barriers, reported unmet need for condoms was low. there is an urgent need for renewed condom promotion efforts aimed at building demand, in addition to improving physical access, in resource-limited settings with generalized HIV epidemics in sub-Saharan Africa. 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.

  7. A Linkage Learning Genetic Algorithm with Linkage Matrix

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The goal of linkage learning, or building block identification, is the creation of a more effective Genetic Algorithm (GA). This paper proposes a new Linkage Learning Genetic Algorithms, named m-LLGA. With the linkage learning module and the linkage-based genetic operation, m-LLGA is not only able to learn and record the linkage information among genes without any prior knowledge of the function being optimized. It also can use the linkage information stored in the linkage matrix to guide the selection of crossover point. The preliminary experiments on two kinds of bounded difficulty problems and a TSP problem validated the performance of m-LLGA. The m-LLGA learns the linkage of different building blocks parallel and therefore solves these problems effectively; it can also reasonably reduce the probability of building blocks being disrupted by crossover at the same time give attention to getting away from local minimum.

  8. Cosmopolitan linkage disequilibrium maps

    Directory of Open Access Journals (Sweden)

    Gibson Jane

    2005-03-01

    Full Text Available Abstract Linkage maps have been invaluable for the positional cloning of many genes involved in severe human diseases. Standard genetic linkage maps have been constructed for this purpose from the Centre d'Etude du Polymorphisme Humain and other panels, and have been widely used. Now that attention has shifted towards identifying genes predisposing to common disorders using linkage disequilibrium (LD and maps of single nucleotide polymorphisms (SNPs, it is of interest to consider a standard LD map which is somewhat analogous to the corresponding map for linkage. We have constructed and evaluated a cosmopolitan LD map by combining samples from a small number of populations using published data from a 10-megabase region on chromosome 20. In support of a pilot study, which examined a number of small genomic regions with a lower density of markers, we have found that a cosmopolitan map, which serves all populations when appropriately scaled, recovers 91 to 95 per cent of the information within population-specific maps. Recombination hot spots appear to have a dominant role in shaping patterns of LD. The success of the cosmopolitan map might be attributed to the co-localisation of hot spots in all populations. Although there must be finer scale differences between populations due to other processes (mutation, drift, selection, the results suggest that a whole-genome standard LD map would indeed be a useful resource for disease gene mapping.

  9. Participation in Non-Formal Learning in EU-15 and EU-8 Countries: Demand and Supply Side Factors

    Science.gov (United States)

    Roosmaa, Eve-Liis; Saar, Ellu

    2012-01-01

    The main purpose of this paper is to provide an in-depth analysis of participation in non-formal learning in different European Union member states. The paper also seeks to extend analysis of the training gap by pursuing the distinction between the supply and the demand for skills. We use aggregate data from the Adult Education Survey (Eurostat)…

  10. Factors and models associated with the amount of hospital care services as demanded by hospitalized patients: a systematic review.

    NARCIS (Netherlands)

    Oostveen, C.J. van; Ubbink, D.T.; Huis in het Veld, J.G.; Bakker, P.J.; Vermeulen, H.

    2014-01-01

    Background: Hospitals are constantly being challenged to provide high-quality care despite ageing populations, diminishing resources, and budgetary restraints. While the costs of care depend on the patients' needs, it is not clear which patient characteristics are associated with the demand for care

  11. The Impacting Factors of University Students’ Tourism Demand%基于SEM的大学生旅游需求影响因素研究

    Institute of Scientific and Technical Information of China (English)

    莫琨; 王淑华

    2014-01-01

    To find out the primary and secondary factors that affect college students’ travel demand,we analysed college students’ tourism demand influence factors. Firstly we build scale,analyse each variable using exploratory factor analysis,confirmatory factor analysis and independent samples T test,and build a three-dimensional model, covering the three major factors that affect college students’ travel demand. The conclusions are as follows.①Attitude is the first factor influencing factors,the second is motivation factors,the final is objective factors.②Attitude factors and motivation factors interact each other,which means that university students’ tourist motives attitude or a party change will affect the other party,commonly affect college students’ travel demand. ③Different gender,census register to variables are significant difference.%为探析出影响大学生旅游需求的主次因素,并对大学生旅游需求影响因素进行深度分析.首先构建量表,然后对各变量进行探索性因子分析、验证性因子分析和独立样本T检验,构建出一个三维模型,涵盖了影响大学生旅游需求的三大方面因素,最后得出以下结论:①态度因素为首要影响因素,其次是动机因素,最后是客观因素.②态度因素和动机因素相互作用,即大学生旅游态度或动机一方的改变都会影响另一方,共同影响着大学生旅游需求.③不同性别、户籍对指标变量存在显著差异.

  12. Factores relacionados con la demanda de atención médica durante el climaterio Factors related to the demand of medical attention during the climacteric

    Directory of Open Access Journals (Sweden)

    Elodia Rivas Alpízar

    2006-08-01

    menopause, as well as the factors connected with the request of medical attention, which was made by women aged 45-54, with preuniverstiy educational level, with very disturbing climacteric symptoms and with an adequate knowledge about climacteric/menopause. Among the reasons not to demand medical care, it was found that 14.7 % of the females referred having no time, in spite of presenting annoying symptoms. Most of the women had gender overload and inadequate knowledge on climacteric/menopause. To conclude, it is the first time in our setting that the social and biological factors motivating or not to seek medical care during the climacteric are reported.

  13. From Enclave to Linkage Economies?

    DEFF Research Database (Denmark)

    Hansen, Michael W.

    and local enterprises by themselves will indeed produce linkages, the scope, depth and development impacts of linkages eventually depend on government intervention. Resource-rich African countries’ governments are aware of this and linkage promotion is increasingly becoming a key element...

  14. CURRENCY LINKAGES AMONG ASEAN

    OpenAIRE

    CHIN LEE; M. Azali

    2010-01-01

    The purpose of this study is to examine the potential linkages among ASEAN-5 currencies, in particular the possibility of a Singapore dollar bloc during the pre- and post-crisis periods by using the Johansen multivariate cointegration test and the Granger causality test. Significant nonstationarity and the presence of unit roots were documented for each currency under both study periods. Using ASEAN-4 exchange rates against the Singapore dollar, the Johansen cointegration test showed that the...

  15. Demanding Satisfaction

    Science.gov (United States)

    Oguntoyinbo, Lekan

    2010-01-01

    It was the kind of crisis most universities dread. In November 2006, a group of minority student leaders at Indiana University-Purdue University Indianapolis (IUPUI) threatened to sue the university if administrators did not heed demands that included providing more funding for multicultural student groups. This article discusses how this threat…

  16. Multicentre, randomized, open-label study of on-demand treatment with two prophylaxis regimens of recombinant coagulation factor IX in haemophilia B subjects.

    Science.gov (United States)

    Valentino, L A; Rusen, L; Elezovic, I; Smith, L M; Korth-Bradley, J M; Rendo, P

    2014-05-01

    Few randomized studies have reported on the use of factor IX (FIX) for secondary prophylaxis in haemophilia B patients. This study aimed to evaluate the efficacy and safety of two secondary prophylaxis regimens of recombinant coagulation FIX, nonacog alfa, compared with on-demand therapy. Male subjects aged 6-65 years with severe or moderately severe haemophilia B (FIX:C ≤ 2, n = 50) and ≥12 bleeding episodes (including ≥6 haemarthroses episodes) within 12 months of study participation were enrolled in this multicentre, randomized, open-label, four-period crossover trial. The primary measure was the annualized bleeding rate (ABR) of two prophylactic regimens vs. on-demand therapy. In the intent-to-treat group, mean ABR values were 35.1, 2.6 and 4.6 for the first on-demand period, the 50 IU kg(-1) twice-weekly period, and the 100 IU kg(-1) once-weekly period respectively. Differences in ABR between the first on-demand period and both prophylaxis regimens were significant (P < 0.0001); no significant differences were observed between prophylaxis regimens (P = 0.22). Seven serious adverse events occurred in five subjects, none related to study drug. Results demonstrated that secondary prophylaxis therapy with nonacog alfa 50 IU kg(-1) twice weekly or 100 IU kg(-1) once weekly reduced ABR by 89.4% relative to on-demand treatment. Both prophylaxis regimens demonstrated favourable safety profiles in subjects with haemophilia B.

  17. Human Capital Linkages to Labour Productivity: Implications from Thai Manufacturers

    Science.gov (United States)

    Rukumnuaykit, Pungpond; Pholphirul, Piriya

    2016-01-01

    Human capital investment is a necessary condition for improving labour market outcomes in most countries. Empirical studies to investigate human capital and its linkages on the labour demand side are, however, relatively scarce due to limitations of firm-level data-sets. Using firm-level data from the Thai manufacturing sector, this paper aims to…

  18. Human Capital Linkages to Labour Productivity: Implications from Thai Manufacturers

    Science.gov (United States)

    Rukumnuaykit, Pungpond; Pholphirul, Piriya

    2016-01-01

    Human capital investment is a necessary condition for improving labour market outcomes in most countries. Empirical studies to investigate human capital and its linkages on the labour demand side are, however, relatively scarce due to limitations of firm-level data-sets. Using firm-level data from the Thai manufacturing sector, this paper aims to…

  19. A Statistical Approach to Crime Linkage

    OpenAIRE

    Porter, Michael D.

    2014-01-01

    The object of this paper is to develop a statistical approach to criminal linkage analysis that discovers and groups crime events that share a common offender and prioritizes suspects for further investigation. Bayes factors are used to describe the strength of evidence that two crimes are linked. Using concepts from agglomerative hierarchical clustering, the Bayes factors for crime pairs are combined to provide similarity measures for comparing two crime series. This facilitates crime series...

  20. Demand Uncertainty

    DEFF Research Database (Denmark)

    Nguyen, Daniel Xuyen

    This paper presents a model of trade that explains why firms wait to export and why many exporters fail. Firms face uncertain demands that are only realized after the firm enters the destination. The model retools the timing of uncertainty resolution found in productivity heterogeneity models...... the high rate of exit seen in the first years of exporting. Finally, when faced with multiple countries in which to export, some firms will choose to sequentially export in order to slowly learn more about its chances for success in untested markets....

  1. A generalization of Kempe's linkages

    Institute of Scientific and Technical Information of China (English)

    MAO De-can; LUO Yao-zhi; YOU Zhong

    2007-01-01

    A new, general type of planar linkages is presented, which extends the classical linkages developed by Kempe consisting of two single-looped kinematic chains of linkages, interconnected by revolute hinges. Together with a locking device, these new linkages have only one degree of freedom (DOF), which makes them ideal for serving as deployable structures for different purposes. Here, we start with a fresh matrix method of analysis for double-loop planar linkages, using 2D transformation matrices and a new symbolic notation. Further inspection for one case of Kempe's linkages is provided. Basing on the inspection, by means of some novel algebraic and geometric techniques, one particularly fascinating solution was found. Physical models were built to show that the derivation in this paper is valid and the new mechanisms are correct.

  2. [Healthcare management of an epilepsy clinic: factors involved in the demand for health care and clinical situation of patients].

    Science.gov (United States)

    García-Martín, Guillermina; Martín-Reyes, Guillermina; Dawid-Milner, Marc Stefan; Chamorro-Muñoz, M Isabel; Pérez-Errazquin, Francisco; Romero-Acebal, Manuel

    2013-05-16

    Introduccion. La epilepsia es una enfermedad cronica que implica un seguimiento periodico del paciente a largo plazo, lo que supone un aumento del numero de pacientes visitados con el tiempo y, por tanto, un coste al sistema sanitario. Objetivo. Determinar los factores implicados en el tiempo para la siguiente visita de un paciente epileptico. Pacientes y metodos. Seleccion de pacientes durante un ano que acuden consecutivamente a consulta de epilepsia de nuestro hospital. Se analiza su situacion clinica y relacion con el consejo medico dado, y los factores implicados en el tiempo transcurrido hasta la siguiente visita mediante modelos econometricos predictivos. Resultados. Existe una clara asociacion entre la situacion clinica del paciente y la modificacion del tratamiento propuesta por el neurologo en la visita anterior. Los factores implicados en el tiempo hasta la siguiente visita fueron frecuencia de crisis, efectos adversos medicamentosos, sobre todo los que afectan a la cognicion, y consejo medico al paciente. No resultaron significativos la politerapia, los trastornos psicoafectivos ni la situacion social del paciente. Conclusiones. El seguimiento en una consulta especifica de epilepsia mejora la situacion del paciente. Se trata del primer analisis de demanda asistencial en pacientes con epilepsia realizado mediante metodos econometricos y desde una perspectiva mixta medico-paciente. Dado que los factores que determinan el tiempo para la siguiente visita son modificables, podria disminuir el numero de visitas al ano, mejorando la situacion clinica de los pacientes. Proponemos una mayor duracion por visita para poder incidir en ello y reducir costes a largo plazo.

  3. A Formalization of Linkage Analysis

    DEFF Research Database (Denmark)

    Ingolfsdottir, Anna; Christensen, A.I.; Hansen, Jens A.

    In this report a formalization of genetic linkage analysis is introduced. Linkage analysis is a computationally hard biomathematical method, which purpose is to locate genes on the human genome. It is rooted in the new area of bioinformatics and no formalization of the method has previously been ...

  4. A Formalization of Linkage Analysis

    DEFF Research Database (Denmark)

    Ingolfsdottir, Anna; Christensen, A.I.; Hansen, Jens A.

    In this report a formalization of genetic linkage analysis is introduced. Linkage analysis is a computationally hard biomathematical method, which purpose is to locate genes on the human genome. It is rooted in the new area of bioinformatics and no formalization of the method has previously been...

  5. [Foreign dentures and dental tourism--willingness-to-pay and factors influencing the demand for foreign dental prosthesis in Germany].

    Science.gov (United States)

    Köberlein, J; Klingenberger, D

    2011-07-01

    With the progressive realisation of the single European market, public interest has been directed towards cross-border healthcare services to an increasing extent. More and more dentures are being imported into Germany from foreign countries. Furthermore, patients are becoming ever more mobile, travelling to other countries to receive prosthetic treatment from dentists. The objective of this evaluation was to determine by means of a dedicated questionnaire the patients' individual preferences for foreign dentures and the potential savings. 1 368 individuals between the ages of 30 and 75 years were interviewed within a representative omnibus survey. The evaluation of the individual willingness-to-pay included 4 treatment scenarios, which were assessed by the participants in a "bidding game". Participants could choose between a "crown scenario" and an "implant scenario", both with the subcategories "foreign dentures" and "dental tourism". The direct comparison revealed a preference for the "foreign dentures" option over "dental tourism". Average willingness-to-pay for the dental tourism option in the crown scenario was calculated as 80 Euro, and in the implant scenario as 280 Euro less in comparison with the willingness-to-pay for the foreign dentures option. The willingness to switch to a less expensive dentist was one of the main determinants in the causal explanation for the variance in willingness-to-pay. Quality proved to be the decisive criterion and was indicated by 92.4% participants. A lower price for dentures played a subordinate role and was only stated as the decisive factor by 31.1% participants. In conclusion, the results clearly indicate that the decision for or against foreign dentures and the extent of willingness-to-pay depends on a range of criteria, of which "price" is only one and not the decisive factor. © Georg Thieme Verlag KG Stuttgart · New York.

  6. Groebner bases via linkage

    CERN Document Server

    Gorla, Elisa; Nagel, Uwe

    2010-01-01

    In this paper, we give a sufficient condition for a set $\\mathal G$ of polynomials to be a Gr\\"obner basis with respect to a given term-order for the ideal $I$ that it generates. Our criterion depends on the linkage pattern of the ideal $I$ and of the ideal generated by the initial terms of the elements of $\\mathcal G$. We then apply this criterion to ideals generated by minors and pfaffians. More precisely, we consider large families of ideals generated by minors or pfaffians in a matrix or a ladder, where the size of the minors or pfaffians is allowed to vary in different regions of the matrix or the ladder. We use the sufficient condition that we established to prove that the minors or pfaffians form a reduced Gr\\"obner basis for the ideal that they generate, with respect to any diagonal or anti-diagonal term-order. We also show that the corresponding initial ideal is Cohen-Macaulay. Our proof relies on known results in liaison theory, combined with a simple Hilbert function computation. In particular, our...

  7. Resource linkages and sustainable development

    Science.gov (United States)

    Anouti, Yahya

    Historically, fossil fuel consumers in most developing hydrocarbon-rich countries have enjoyed retail prices at a discount from international benchmarks. Governments of these countries consider the subsidy transfer to be a means for sharing the wealth from their resource endowment. These subsidies create negative economic, environmental, and social distortions, which can only increase over time with a fast growing, young, and rich population. The pressure to phase out these subsidies has been mounting over the last years. At the same time, policy makers in resource-rich developing countries are keen to obtain the greatest benefits for their economies from the extraction of their exhaustible resources. To this end, they are deploying local content policies with the aim of increasing the economic linkages from extracting their resources. Against this background, this dissertation's three essays evaluate (1) the global impact of rationalizing transport fuel prices, (2) how resource-rich countries can achieve the objectives behind fuel subsidies more efficiently through direct cash transfers, and (3) the economic tradeoffs from deploying local content policies and the presence of an optimal path. We begin by reviewing the literature and building the case for rationalizing transport fuel prices to reflect their direct costs (production), indirect costs (road maintenance) and negative externalities (climate change, local pollutants, traffic accidents and congestion). To do so, we increase the scope of the economic literature by presenting an algorithm to evaluate the rationalized prices in different countries. Then, we apply this algorithm to quantify the rationalized prices across 123 countries in a partial equilibrium setting. Finally, we present the first comprehensive measure of the impact of rationalizing fuel prices on the global demand for gasoline and diesel, environmental emissions, government revenues, and consumers' welfare. By rationalizing transport fuel

  8. “Souls of the ancestor that knock us out” and other tales. A qualitative study to identify demand-side factors influencing malaria case management in Cambodia

    Directory of Open Access Journals (Sweden)

    O’Connell Kathryn A

    2012-10-01

    Full Text Available Abstract Background Appropriate case management of suspected malaria in Cambodia is critical given anti-malarial drug resistance in the region. Improving diagnosis and the use of recommended malarial treatments is a challenge in Cambodia where self-treatment and usage of drug cocktails is widespread, a notable difference from malaria treatment seeking in other countries. This qualitative study adds to the limited evidence base on Cambodian practices, aiming to understand the demand-side factors influencing treatment-seeking behaviour, including the types of home treatments, perceptions of cocktail medicines and reasons for diagnostic testing. The findings may help guide intervention design. Methods The study used in-depth interviews (IDIs (N = 16 and focus group discussions (FGDs (N = 12 with Cambodian adults from malaria-endemic areas who had experienced malaria fever in the previous two weeks. Data were analysed using NVivo software. Results Findings suggest that Cambodians initially treat suspected malaria at home with home remedies and traditional medicines. When seeking treatment outside the home, respondents frequently reported receiving a cocktail of medicines from trusted providers. Cocktails are perceived as less expensive and more effective than full-course, pre-packaged medicines. Barriers to diagnostic testing include a belief in the ability to self-diagnose based on symptoms, cost and reliance on providers to recommend a test. Factors that facilitate testing include recommendation by trusted providers and a belief that anti-malarial treatment for illnesses other than malaria can be harmful. Conclusions Treatment-seeking behaviour for malaria in Cambodia is complex, driven by cultural norms, practicalities and episode-related factors. Effective malaria treatment programmes will benefit from interventions and communication materials that leverage these demand-side factors, promoting prompt visits to facilities for suspected

  9. Prevalence and risk factors for microalbuminuria in a cross-sectional study of type-2 diabetic patients in Indonesia : a subset of DEMAND study

    Directory of Open Access Journals (Sweden)

    Sidartawan Soegondo

    2009-06-01

    Full Text Available Aims Microalbuminuria (MA is a strong predictor of diabetic nephropathy and cardiovascular morbidity and mortality in patients with type-2 DM. The present study aimed to gather information on the prevalence and risk factors for MA in Indonesian patients with type-2 DM.Methods The DEMAND study was an international open cross-sectional 1-day survey on microalbuminuria prevalence and its risk factors in type-2 diabetic patients. This study reports the results of the Indonesian survey which was performed in primary care practice in Indonesia from June to December 2003. Normotensive or hypertensive adult patients of both genders with type-2 DM without known proteinuria and/or kidney disease were recruited into the study. Patients with known pregnancy, having menstruation or acute fever were excluded. A single urinary albumin/creatinine test was carried out in all patients.Results A total of 770 patients were eligible for analysis. Approximately 80% of the patients had micro-/ macroalbuminuria, while renal insufficiency was detected in about 36% of the 433 patients with available data. Target HbA1c (< 7% was reached by only 40% of the 118 patients who had HbA1c values. Most antidiabetic treatment prescribed was oral (82%, while insulin was used by only 14% of patients. Goal BP (< 130/80 mm Hg was achieved in only 9% of patients. The frequency of patients receiving antihypertensives was 52%, statins 18%, and aspirin 26%. The most frequently used antihypertensives were RAS blockers (45%, while diuretics were used in 7 % of the patients. The family history of DM was found in 43% of patients, the history of retinopathy in 16%, diabetic foot 9%, and history of smoking in 20% of patients.Conclusion These data reveal that Indonesia has one of the highest frequencies of silent diabetic kidney disease seen in any national group in the global DEMAND Study. Early detection, monitoring of vascular complications, and more aggressive multifactorial treatment aiming

  10. Demand-side financing for maternal and newborn health: what do we know about factors that affect implementation of cash transfers and voucher programmes?

    Science.gov (United States)

    Hunter, Benjamin M; Murray, Susan F

    2017-08-31

    Demand-side financing (DSF) interventions, including cash transfers and vouchers, have been introduced to promote maternal and newborn health in a range of low- and middle-income countries. These interventions vary in design but have typically been used to increase health service utilisation by offsetting some financial costs for users, or increasing household income and incentivising 'healthy behaviours'. This article documents experiences and implementation factors associated with use of DSF in maternal and newborn health. A secondary analysis (using an adapted Supporting the Use of Research Evidence framework - SURE) was performed on studies that had previously been identified in a systematic review of evidence on DSF interventions in maternal and newborn health. The article draws on findings from 49 quantitative and 49 qualitative studies. The studies give insights on difficulties with exclusion of migrants, young and multiparous women, with demands for informal fees at facilities, and with challenges maintaining quality of care under increasing demand. Schemes experienced difficulties if communities faced long distances to reach participating facilities and poor access to transport, and where there was inadequate health infrastructure and human resources, shortages of medicines and problems with corruption. Studies that documented improved care-seeking indicated the importance of adequate programme scope (in terms of programme eligibility, size and timing of payments and voucher entitlements) to address the issue of concern, concurrent investments in supply-side capacity to sustain and/or improve quality of care, and awareness generation using community-based workers, leaders and women's groups. Evaluations spanning more than 15 years of implementation of DSF programmes reveal a complex picture of experiences that reflect the importance of financial and other social, geographical and health systems factors as barriers to accessing care. Careful design of DSF

  11. Demand for long acting and permanent methods of contraceptives and factors for non-use among married women of Goba Town, Bale Zone, South East Ethiopia

    Directory of Open Access Journals (Sweden)

    Takele Abulie

    2012-10-01

    Full Text Available Abstract Background Contraceptive use including short acting, long acting and permanent methods positively influence the socio-economic development of a nation by allowing families to space and limit their family size to their economic capacity. Demand for LAPMs of contraception as detrmined by utilization and unmet need for LAPMs of contraception can provide realiable information for providers. Objective To determine the utilization of long acting and permanent contraception and its associated factors among married women of Goba town, South East Ethiopia. Methods A cross sectional community based study was conducted among 734 systematically selected married women of reproductive age in Goba town in September/ 2009. A structured and pretested, interview questionaire was used to collect data on socio-demographic, behavioral factors and data related to demand for LAPMs of contraception. Data were analyzed using EPI INFO and SPSS version 16. Result The demand for Long Acting and Permanent Methods (LAPMs of contraception was 18.1%. Utilization of LAPMs of contraception in the town was 64 (8.7% and the unmet need for LAPMs was 69 (9.4%. Information on LAPMs in the town was 636 (86.6%. Media (radio and television was the major sources of information 641 (87.3%. The use of LAPMs was significatly associated with ever use AOR[17.43, 95% CI:9.19, 33.03], number of times discussions made on methods AOR[4.6, 95% CI: 1.72,12.17] and main decider of using methods AOR[ 2.2, 95% CI:1.03, 4.65]. It was not associated with socio-demographic variables. Conclusion and recommendation The utilization of LAPMs in the town was less although higher than the Ethiopian demographic and health survey 2005 result. Moreover, there was a considerable unmet need. Increase the method mix of LAPMs by incorporating varaies of implnats in order to increase utilization. Proper counseling of client and partners discussion were some of the recommendation forwarded.

  12. Emergency Linkage Mode of Power Enterprise

    Directory of Open Access Journals (Sweden)

    Feng Jie

    2016-01-01

    Full Text Available Power emergency disposal needs take full advantage of the power enterprise within the external emergency power and resources. Based on analyzing and summarizing the relevant experience of domestic and foreign emergency linkage, this paper draws the Emergency Linkage subjects, Emergency Linkage contents, Emergency Linkage level, which are three key elements if power enterprise Emergency Linkage. Emergency Linkage subjects are divided into the two types of inner subjects and the external body; Emergency Linkage contents are in accordance with four phases of prevention, preparedness, response and recovery; Emergency Linkage level is divided into three levels of enterprise headquarter, provincial enterprise and incident unite. Binding power enterprise emergency management practice, this paper studies the internal Emergency Linkage modes (including horizontal mode and vertical mode, external Emergency Linkage mode and comprehensive Emergency Linkage Mode of power enterprise based on Fishbone Diagram and Process Management Technology.

  13. STAKEHOLDER LINKAGES FOR SUSTAINABLE LAND ...

    African Journals Online (AJOL)

    Osondu

    stakeholder interactions for SLM in the study areas. Key words: Stakeholders; farmer-expert linkages; resource management; Ethiopia ... management practices in many parts of Africa. Farmers .... chosen with consideration of distance to the.

  14. Data Linkage: A powerful research tool with potential problems

    Directory of Open Access Journals (Sweden)

    Scott Ian

    2010-12-01

    Full Text Available Abstract Background Policy makers, clinicians and researchers are demonstrating increasing interest in using data linked from multiple sources to support measurement of clinical performance and patient health outcomes. However, the utility of data linkage may be compromised by sub-optimal or incomplete linkage, leading to systematic bias. In this study, we synthesize the evidence identifying participant or population characteristics that can influence the validity and completeness of data linkage and may be associated with systematic bias in reported outcomes. Methods A narrative review, using structured search methods was undertaken. Key words "data linkage" and Mesh term "medical record linkage" were applied to Medline, EMBASE and CINAHL databases between 1991 and 2007. Abstract inclusion criteria were; the article attempted an empirical evaluation of methodological issues relating to data linkage and reported on patient characteristics, the study design included analysis of matched versus unmatched records, and the report was in English. Included articles were grouped thematically according to patient characteristics that were compared between matched and unmatched records. Results The search identified 1810 articles of which 33 (1.8% met inclusion criteria. There was marked heterogeneity in study methods and factors investigated. Characteristics that were unevenly distributed among matched and unmatched records were; age (72% of studies, sex (50% of studies, race (64% of studies, geographical/hospital site (93% of studies, socio-economic status (82% of studies and health status (72% of studies. Conclusion A number of relevant patient or population factors may be associated with incomplete data linkage resulting in systematic bias in reported clinical outcomes. Readers should consider these factors in interpreting the reported results of data linkage studies.

  15. A cross-sectional study of the relationship between job demand-control, effort-reward imbalance and cardiovascular heart disease risk factors

    Directory of Open Access Journals (Sweden)

    Söderberg Mia

    2012-12-01

    Full Text Available Abstract Background This cross-sectional study explored relationships between psychosocial work environment, captured by job demand-control (JDC and effort-reward imbalance (ERI, and seven cardiovascular heart disease (CHD risk factors in a general population. Method The sampled consists of randomly-selected men and women from Gothenburg, Sweden and the city’s surrounding metropolitan areas. Associations between psychosocial variables and biomarkers were analysed with multiple linear regression adjusted for age, smoking, education and occupational status. Results The study included 638 men and 668 women aged 24–71. Analysis between JDC and CHD risk factors illustrated that, for men, JDC was associated with impaired scores in several biomarkers, especially among those in high strain jobs. For women, there were no relationships between JDC and biomarkers. In the analysis of links between ERI and CHD risk factors, most associations tested null. The only findings were raised triglycerides and BMI among men in the fourth quartile of the ERI-ratio distribution, and lowered LDL-cholesterol for women. An complementary ERI analysis, combining high/low effort and reward into categories, illustrated lowered triglycerides and elevated HDL-cholesterol values among women reporting high efforts and high rewards, compared to women experiencing low effort and high reward. Conclusions There were some associations between psychosocial stressors and CHD risk factors. The cross-sectional design did not allow conclusions about causality but some results indicated gender differences regarding sensitivity to work stressors and also how the models might capture different psychosocial dimensions.

  16. Some remarks about flux linkage and inductance

    Directory of Open Access Journals (Sweden)

    S. Kurz

    2004-01-01

    Full Text Available In the area of computational electromagnetics there is an increasing demand for various coupled simulations. One example is the coupling between field and circuit simulation for the description of electromagnetic devices. In the context of such couplings, theoretical questions arise as well. How can a field device be represented as an equivalent multiport circuit element? What is meant by flux linkage if the considered conductors are not filamentary? What is meant by inductance if the magnetic media exhibit nonlinear behaviour? These questions and their answers are not new. However, according to the author’s view, these issues are not sufficiently addressed in the usual textbooks. The aim of the paper is therefore to (hopefully answer the questions concisely and correctly. The modern language of differential forms will be employed for this purpose.

  17. DEMAND AND PRICES

    Directory of Open Access Journals (Sweden)

    VĂDUVA MARIA

    2014-08-01

    Full Text Available Studying the consumer’s behavior by the ordinal approach of utility with the help of indifference curves allows us to deduce the two “movement laws of demand” in this chapter: the demand for a “normal” good is decreasing function of its price and an increasing function of income. We will use the elasticity concept to measure the intensity of the relation that is established between the demand, on the one hand, and prices or income, on the other hand: elasticity – price, direct and crossed, and elasticity – income. We can classify the goods in many categories, depending on the values that this elasticity takes. The demand elasticity can be determined depending on price and income. It reflects the proportion in which the demand for different products changes with the modification of the consumers’ income, the other factors remaining constant. The elasticity compared to the income is a demonstration of legality from the consumer’s sphere, which determines a certain hierarchy of the needs of each population category in a certain level of income. The movement of prices orients both the options and decisions of producers, namely the most useful productions and the most efficient investments, as well as the consumers’ options and decisions on the most advantageous buying of goods and services that they need. The prices appear as a “signal system” coordinating and making coherence the economic agents’ decisions – producers, consumers and population.

  18. Factores relacionados con la demanda de atención médica para el climaterio Factors related to medical care demand for climaterium

    Directory of Open Access Journals (Sweden)

    Elodia Rivas Alpízar

    2003-12-01

    Full Text Available A partir de la menopausia se incrementa la morbimortalidad femenina por afecciones como la aterosclerosis, la osteoporosis y el cáncer, por lo que aumentan los cuidados a las pacientes y la atención médica, tema poco estudiado en nuestro medio y que contribuiría a programar con mayor especificidad los servicios de salud para esta etapa de la vida. Con el objetivo de identificar los factores relacionados con la solicitud de ayuda médica por la mujer de edad mediana, se realizó un estudio descriptivo transversal, en el que se entrevistaron 311 mujeres, que se corresponden con el total de féminas de 40-59 años atendidas en 4 consultorios del médico de la familia del Policlínico Área III en Cienfuegos, seleccionados mediante muestreo por conglomerado monoetápico. El 63 % de las mujeres estuvo en etapa de posmenopausia. El 17,2 % refirió síndrome climatérico molesto. El 21,2 % tuvo conocimiento adecuado sobre climaterio/menopausia. El 29,9 % solicitó ayuda médica y los factores relacionados con esta fueron: el nivel escolar de preuniversitario, tener síntomas climatéricos muy molestos, poseer un conocimiento adecuado sobre climaterio/menopausia y estar en la etapa temprana de la posmenopausia. En conclusión, por primera vez en nuestro medio se identifican los factores biológicos (síndrome climatérico molesto y etapa tardía de la posmenopausia y sociales (escolaridad y conocimientos relacionados con la solicitud de ayuda médica durante el período climatérico.From menopause on, morbidity and mortality rates increase in females due to atherosclerosis, osteoporosis and cancer, so care and medical assistance services also increase; this is a topic that has been poorly studied in our context, even though it may contribute to plan more specific health services for this stage of life. With the aim of identifying the factors related to request of medical support by middle-aged women, a cross-sectional descriptive study was performed

  19. Human bZIP transcription factor gene NRL: structure, genomic sequence, and fine linkage mapping at 14q11.2 and negative mutation analysis in patients with retinal degeneration.

    Science.gov (United States)

    Farjo, Q; Jackson, A; Pieke-Dahl, S; Scott, K; Kimberling, W J; Sieving, P A; Richards, J E; Swaroop, A

    1997-10-15

    The NRL gene encodes an evolutionarily conserved basic motif-leucine zipper transcription factor that is implicated in regulating the expression of the photoreceptor-specific gene rhodopsin. NRL is expressed in postmitotic neuronal cells and in lens during embryonic development, but exhibits a retina-specific pattern of expression in the adult. To understand regulation of NRL expression and to investigate its possible involvement in retinopathies, we have determined the complete sequence of the human NRL gene, identified a polymorphic (CA)n repeat (identical to D14S64) within the NRL-containing cosmid, and refined its location by linkage analysis. Since a locus for autosomal recessive retinitis pigmentosa (arRP) has been linked to markers at 14q11 and since mutations in rhodopsin can lead to RP, we sequenced genomic PCR products of the NRL gene and of the rhodopsin-Nrl response element from a panel of patients representing independent families with inherited retinal degeneration. The analysis did not reveal any causative mutations in this group of patients. These investigations provide the basis for delineating the DNA sequence elements that regulate NRL expression in distinct neuronal cell types and should assist in the analysis of NRL as a candidate gene for inherited diseases/syndromes affecting visual function. Copyright 1997 Academic Press.

  20. Key factors that influence the demand and the consumption of electric power in solar home systems; Principais fatores que influenciam a demanda e o consumo de energia eletrica em sistemas fotovoltaicos domiciliares

    Energy Technology Data Exchange (ETDEWEB)

    Morante, Federico; Zilles, Roberto [Universidade de Sao Paulo (USP), SP (Brazil). Programa Interunidades de Pos Graduacao em Energia. Lab. de Sistemas Fotovoltaicos], e-mail: fmorante@iee.usp.br, e-mail: zilles@iee.usp.br

    2004-07-01

    From the results obtained with a field research looking for to understanding the behavior of the electric energy demand in Solar Home Systems, the aleatory influence factors in the demand was identified These can be contained in technical, management, psychological, geographical, demographic, socio cultural and economic factors. The purpose of this paper is to describe each of them and, simultaneously, present some registration discover with the field work. The survey involved 178 people and 13 rural communities located in the States of Sao Paulo, Pernambuco and Amazonas and, besides, in the Puno area, in Peru. Ten of those communities are electrified with photovoltaic systems and three with the conventional electric grid. (author)

  1. Demand scenarios, worldwide

    Energy Technology Data Exchange (ETDEWEB)

    Schaefer, A. [Massachusetts Inst. of Technology, Center for Technology, Policy and Industrial Development and the MIT Joint Program on the Science and Policy of Global Change, Cambridge, MA (United States)

    1996-11-01

    Existing methods are inadequate for developing aggregate (regional and global) and long-term (several decades) passenger transport demand scenarios, since they are mainly based on simple extensions of current patterns rather than causal relationships that account for the competition among transport modes (aircraft, automobiles, buses and trains) to provide transport services. The demand scenario presented in this paper is based on two empirically proven invariances of human behavior. First, transport accounts for 10 to 15 percent of household total expenditures for those owning an automobile, and around 5 percent for non-motorized households on average (travel money budget). Second, the mean time spent traveling is approximately one hour per capita per day (travel time budget). These two budgets constraints determine the dynamics of the scenario: rising income increases per capita expenditure on travel which, in turn, increase demand for mobility. Limited travel time constraints travelers to shift to faster transport systems. The scenario is initiated with the first integrated historical data set on traffic volume in 11 world regions and the globe from 1960 to 1990 for all major modes of motorized transport. World average per capita traffic volume, which was 1,800 kilometers in 1960 and 4,2090 in 1990, is estimated to rise to 7,900 kilometers in 2020 - given a modest average increase in Gross World Product of 1.9% per year. Higher economic growth rates in Asian regions result in an increase in regional per capita traffic volume up to a factor of 5.3 from 1990 levels. Modal splits continue shifting to more flexible and faster modes of transport. At one point, passenger cars can no longer satisfy the increasing demand for speed (i.e. rising mobility within a fixed time budget). In North America it is estimated that the absolute traffic volume of automobiles will gradually decline starting in the 2010s. (author) 13 figs., 6 tabs., 35 refs.

  2. Dubin's Minimal Linkage Construct Revisited.

    Science.gov (United States)

    Rogers, Donald P.

    This paper contains a theoretical analysis and empirical study that support the major premise of Robert Dubin's minimal-linkage construct-that restricting communication links increases organizational stability. The theoretical analysis shows that fewer communication links are associated with less uncertainty, more redundancy, and greater…

  3. Constructing dense genetic linkage maps

    NARCIS (Netherlands)

    Jansen, J.; Jong, de A.G.; Ooijen, van J.W.

    2001-01-01

    This paper describes a novel combination of techniques for the construction of dense genetic linkage maps. The construction of such maps is hampered by the occurrence of even small proportions of typing errors. Simulated annealing is used to obtain the best map according to the optimality criterion:

  4. North-South Business Linkages

    DEFF Research Database (Denmark)

    Sørensen, Olav Jull; Kuada, John

    2006-01-01

    Based on empirical studies of linkages between TNCs and local firms in India, Malaysia, Vietnam, Ghana and South Africa, five themes are discussed and related to present theoretical perspectives. The themes are (1) Linakge Governance; (2) Globalisation and the dynamics in developing countries (the...

  5. Exploitation of linkage learning in evolutionary algorithms

    CERN Document Server

    Chen, Ying-ping

    2010-01-01

    The exploitation of linkage learning is enhancing the performance of evolutionary algorithms. This monograph examines recent progress in linkage learning, with a series of focused technical chapters that cover developments and trends in the field.

  6. Demand Forecasting Errors

    OpenAIRE

    Mackie, Peter; Nellthorp, John; Laird, James

    2005-01-01

    Demand forecasts form a key input to the economic appraisal. As such any errors present within the demand forecasts will undermine the reliability of the economic appraisal. The minimization of demand forecasting errors is therefore important in the delivery of a robust appraisal. This issue is addressed in this note by introducing the key issues, and error types present within demand fore...

  7. Factors Influencing Farmers' Willingness to Join Increase-Decrease Linkage Program of Rural-Urban Construction Land%农户参与增减挂钩项目意愿的影响因素研究

    Institute of Scientific and Technical Information of China (English)

    张贞; 高金权; 简广宁

    2013-01-01

    The planning of linking the increase in land used for urban construction with the decrease in land used for rural construction is an effective method to promote balance of land. Taking the practice in Xiazhuzhuang, Tianjin City as a case, this research combines the peasant household surveys with the multinomial Logistic model to analyze the factors that influence the willingness of farmers to participate in the increase-decrease linkage program of land use. The results indicate that the household heads' gender, education level and understanding of this policy are positive driving force in farmers' willingness, while the house conditions and living facilities are the major factors preventing them from joining the program. Meanwhile, the approaches to learning the policy and the policy response obviously affect their willingness. It suggested that the government should strengthen the popularization of the policy and protect the farmers' rights so as to ensure the successful implementation of the policy.%以天津市武清区下朱庄挂钩项目为例,采用参与性农户调查与多元Logistic方法相结合,分析农户参与挂钩项目的意愿及其影响因素.研究结果表明:户主性别、文化程度和对政策的了解程度是农户参与意愿的正向驱动力;而房屋情况和生活基础设施配套是限制农户参与的主导因素;政策获知途径与政策响应原因对农户响应意愿具有显著影响.只有政府加大农户对政策的宣传,使农户真正理解该政策,并保障农户利益不受侵害,才能成功有效地推动挂钩政策的实施.

  8. The interpersonal process model of demand/withdraw behavior.

    Science.gov (United States)

    Baucom, Brian R; Dickenson, Janna A; Atkins, David C; Baucom, Donald H; Fischer, Melanie S; Weusthoff, Sarah; Hahlweg, Kurt; Zimmermann, Tanja

    2015-02-01

    The demand/withdraw interaction pattern is a destructive cycle of relationship communication behavior that is associated with negative individual and relationship outcomes. Demand/withdraw behavior is thought to be strongly linked to partners' emotional reactions, but current theories are inconsistent with empirical findings. The current study proposes the interpersonal process model of demand/withdraw behavior, which includes linkages between each partners' emotional reactions and the interpersonal behavior of demanding and withdrawing. Data come from problem solving discussions of 55 German couples with observationally coded demand/withdraw behavior and fundamental frequency (f₀) to measure vocally encoded emotional arousal. Actor-partner interdependence models (Kenny, Kashy, & Cook, 2006) were used to examine associations among demand/withdraw behavior and f₀ in the overall discussion and 5-min segments. Significant cross-partner associations emerged for demanding and withdrawing behavior across the whole conversation as well as within 5-min segments, and these associations are partially accounted for by each individual's f₀. When behaviorally coded demanders expressed more vocal arousal, they demanded more and withdrew less while their partners withdrew more. In contrast, when behaviorally coded withdrawers expressed more vocal arousal, their partners demanded less and withdrew more. Findings demonstrate that demand/withdraw behavior varies between couples (i.e., some couples engage in a stronger demand/withdraw cycle than others) and between segments (i.e., when 1 partner increases demanding, the other increases withdrawing). Findings support key elements of the interpersonal process model, showing intra- and interpersonal pathways linking demand/withdraw behavior and emotion and demonstrate the importance of partners' behavioral roles in these linkages.

  9. Poverty nutrition linkages.

    Science.gov (United States)

    Ramachandran, Prema

    2007-10-01

    cent and about half the children are undernourished. While poverty and mortality rates came down by 50 per cent, fertility rate by 40 per cent, the reduction in undernutrition in children is only 20 per cent. National surveys indicate that a third of the children from high income group who have not experienced any deprivations are undernourished. The high undernutrition rates among children appears to be mainly due to high low birthweight rates, poor infant and young child feeding and caring practices. At the other end of the spectrum, surveys in school children from high income groups indicate that between 10-20 per cent are overnourished; the major factor responsible appears to be reduction in physical activity. Some aspects of the rapidly changing, complex relationship between economic status, poverty, dietary intake, nutritional and health status are explored in this review.

  10. The Optimization Design of Six-bar Linkage Mechanism

    Directory of Open Access Journals (Sweden)

    Xiaoli Wang

    2013-07-01

    Full Text Available At present, multi-bar linkage mechanism is one of the most important directions of mechanical presses’ development. Utilizing the typical multi-linkage drawing mechanism of the plunger slide and compounding its parameters scientifically are a fairly effective way to realize the drawing technology demand. This paper established kinematics mode of the six-bar drawing mechanism by bar-group method, and produced simulated system by Visual Basic, which simulated the actual motion of the mechanism. With the objective function-velocity fluctuation in drawing and drawing depth, using chaos genetic algorithm method, carried out optimization design of the mechanism, and acquired several groups’ data. The optimization results showed that their performance in kinematics was improved greatly and had exceeded the original mechanism.  

  11. Factores asociados a la demanda de servicios para la atención del parto en México Factors associated with the demand for delivery care in Mexico

    Directory of Open Access Journals (Sweden)

    Miguel Ángel González-Block

    2010-10-01

    Full Text Available Objetivo. Analizar los factores asociados a la utilización de la institución de atención del parto en México para documentar el proceso de integración funcional de instituciones de salud. Material y métodos. Se utilizó información de mujeres con último parto entre 2000 y 2005 en la Encuesta Nacional de Salud y Nutrición 2006. Se aplicó la prueba de ji cuadrada para probar diferencias entre institución utilizada y aseguramiento. Se usó regresión logística para identificar factores que favorecieron la demanda de instituciones diferentes a las de afiliación de la mujer. Resultados. El 62.6% de mujeres con seguridad social utilizó instituciones de afiliación y 13.4% instituciones públicas. Entre no aseguradas 43.3% utilizó instituciones públicas y 19% seguridad social; 64.3% de afiliadas al Seguro Popular se atendieron en instituciones públicas. Variables de acceso, nivel socioeconómico y condiciones de vida influyeron en la demanda referida. Conclusiones. El traslape para atención de partos institucionales documenta la existencia de integración funcional de facto entre instituciones de salud mexicanas.Objective. Analyze the factors associated with the utilization of delivery care institutions in Mexico in order to document the functional integration of health institutions. Materials and Methods. Based on the 2006 National Health and Nutrition Survey, information from women whose last birth was between 2000 and 2005 was used. Chi square was used to test differences between institutions used and health insurance type. A logistic regression was carried out to identify factors associated with the demand for institutions with which women were not affiliated. Results. Women with social security used in 62% of the cases the institution of their affiliation and 13.4% used public institutions. For uninsured women, 43.3% used public institutions and 19.0% social security institutions; 64.3% of the Seguro Popular affiliates were

  12. Linkages between aggregate formation, porosity and soil chemical properties

    NARCIS (Netherlands)

    Regelink, I.C.; Stoof, C.R.; Rousseva, S.; Weng, L.; Lair, G.J.; Kram, P.; Nikolaidis, N.P.; Kercheva, M.; Banwart, S.; Comans, R.N.J.

    2015-01-01

    Linkages between soil structure and physical–chemical soil properties are still poorly understood due to the wide size-range at which aggregation occurs and the variety of aggregation factors involved. To improve understanding of these processes, we collected data on aggregate fractions, soil

  13. A multilevel analysis of the demands--control model: is stress at work determined by factors at the group level or the individual level?

    Science.gov (United States)

    Van Yperen, N W; Snijders, T A

    2000-01-01

    This study explored the extent to which negative health-related outcomes are associated with differences between work groups and with differences between individuals within work groups using R.A. Karasek's (1979) demands-control model. The sample consisted of 260 employees in 31 working groups of a national bank in the Netherlands. Results suggest that job demands and job control should be conceptualized as having both group- and individual-level foundations. Support for Karasek's demands-control model was found only when these variables were split into the 2 parts, reflecting shared perceptions and employees' subjective assessment, respectively. One of the most appealing practical implications is that absence rates among homogeneous work groups can be reduced by enhancing actual control on the job.

  14. Linkages between development and climate change

    Energy Technology Data Exchange (ETDEWEB)

    Halsnaes, K. [UNEP, Roskilde (Denmark); Verhagen, J. [Plant Res. International, Wageningen (Netherlands); Rovere, E. La [Centro Clima. Centre for Integrated Studies on Climate Change and Environment, Rio de Janeiro (Brazil); Klein, R. [Potsdam Inst. for Climate Impacts Res., PIK, Potsdam (DE); Huq, S. [International Inst. for Environment and Development, IIED, London (United Kingdom)

    2003-11-01

    This paper aims at assessing how the development and climate change literature has considered potential linkages and synergies between general development policies and climate change adaptation and mitigation policies. The starting point for this review is to give an overview of how alternative economic development paradigms can be used as a background for understanding and assessing development and climate linkages. In this way, it is demonstrated how climate change issues are related to basic factors in economic and social development processes, as an introduction to a discussion about how alternative policy recommendations for integrated development and climate policies can be understood in the context of different development paradigms. The last part of the paper returns to the climate change and sustainable development discussion that in recent years has been running in parallel to the Third Assessment of IPCC. This discussion, to a large extent has been dominated by the climate change agenda rather than a broader development policy perspectives, and the paper finally suggests a number of areas where integrated development and climate studies could anchor climate change studies more in the development agenda. (au)

  15. [Linkage to care among new human immunodeficiency virus diagnoses in Spain].

    Science.gov (United States)

    Oliva, Jesús; Malo, Carmen; Fernández, Ana; Izquierdo, Ana; Marcos, Henar; Cevallos, Carlos; Castilla, Jesús; García, Rocio; Díez, Mercedes

    2014-03-01

    To describe linkage to care among new HIV diagnoses in Spain; and to estimate factors associated to linkage to care within three months after diagnosis. The distribution of the time elapsing between the date of HIV diagnosis and the date of first determination of CD4 (considered to be the date of linkage to care) was calculated among new HIV diagnoses in 2010 in the seven Autonomous Regions participating, where data on date of CD4 count was available. Linkage to care was considered «correct» if done within three months after diagnosis. Factors associated to correct linkage to care were estimated using logistic regression. A total of 1769 new HIV diagnoses were included. Of them, 83.1% had evidence of linkage to care within a year, and 75.7% were linked within three months after diagnosis. Being an injectable drug user (IDU) was the only factor inversely associated with linkage to care within 3 months (OR = 0.3; 95% CI: 0.2-0.6). In Spain linkage to care after HIV diagnosis is good, but there is still room for improvement, especially among IDUs. Copyright © 2013 Elsevier España, S.L. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  16. A multilevel analysis of the demands-control model: Is stress at work determined by factors at the group level or the individual level?

    NARCIS (Netherlands)

    Van Yperen, N.W.; Snijders, T.A.B.

    2000-01-01

    This study explored the extent to which negative health-related outcomes are associated with differences between work groups and with differences between individuals within work groups using R. A. Karasek's (1979) demands-control model. The sample consisted of 260 employees in 31 working groups of a

  17. Empirical Analysis of Influence Factors for Cigarette Demands in China%我国卷烟需求影响因素的实证分析

    Institute of Scientific and Technical Information of China (English)

    高福宏; 李卫; 孔宁川

    2012-01-01

    The long-term equilibrium model and dynamic adjustment model for total demand quantity of cigarette in china were established according to the annual data to analyze relation between total sales volume of cigarette and its corresponding economic indicators. The demand of cigarette is mainly decided by GDP, cigarette prices, population and consumption level. The speed of adjusting total sales volume to demand quantity of cigarette is 0.42, namely 42% of the gap between annual cigarette demand quantity and sales volume has been adjusted within the year. It is illustrated that cigarette sales volume in China still has some growth potential to meet the increasing demand of cigarette consumption of residents.%根据年度数据建立我国卷烟需求总量的长期均衡和动态调整模型,对我国卷烟销售总量与相应经济指标之间的影响关系进行实证分析.我国卷烟需求量主要由国内生产总值、卷烟价格、人口总数和居民消费水平四个因素所决定,卷烟销售总量向需求量进行调整的速度为0.42,即卷烟需求量与该年度卷烟销售量之间的缺口有42%的部分在年度内得到调整,说明我国卷烟销售量还有一定的增长空间可以满足居民卷烟消费稳步提高.

  18. Partner influence and in-phase versus anti-phase physiological linkage in romantic couples.

    Science.gov (United States)

    Reed, Rebecca G; Randall, Ashley K; Post, Jessica H; Butler, Emily A

    2013-06-01

    Between-partner physiological linkage can be in-phase (changes in unison), or anti-phase (changes in opposite directions). In the context of conversation we predicted that in-phase linkage would occur when partners exert strong influence on each other; anti-phase linkage would occur due to the behavioral coordination of turn taking. To test this, blood pressure, inter-beat interval, and skin conductance were recorded from 44 heterosexual couples while they discussed how they influence each other's health-related behaviors. Partner influence was assessed in two ways: 1) partners' global perceptions of how they try to influence each other's health; and 2) behavioral manifestations of influence, specifically demand-withdraw behavior. As predicted, both measures of partner influence moderated physiological linkage of blood pressure such that at low levels of influence linkage was "anti-phase" and at high levels linkage was "in-phase." Several alternative hypotheses were ruled out; the effects were not due to relationship conflict, emotional experience, or simply the pattern of blood pressure over time. These results suggest that partner influence may be driving physiological linkage, which may be one avenue through which partners can affect each other's health.

  19. Validation of an instrument to measure inter-organisational linkages in general practice

    Directory of Open Access Journals (Sweden)

    Cheryl Amoroso

    2007-11-01

    Full Text Available Purpose: Linkages between general medical practices and external services are important for high quality chronic disease care. The purpose of this research is to describe the development, evaluation and use of a brief tool that measures the comprehensiveness and quality of a general practice’s linkages with external providers for the management of patients with chronic disease. In this study, clinical linkages are defined as the communication, support, and referral arrangements between services for the care and assistance of patients with chronic disease. Methods: An interview to measure surgery-level (rather than individual clinician-level clinical linkages was developed, piloted, reviewed, and evaluated with 97 Australian general practices. Two validated survey instruments were posted to patients, and a survey of locally available services was developed and posted to participating Divisions of General Practice (support organisations. Hypotheses regarding internal validity, association with local services, and patient satisfaction were tested using factor analysis, logistic regression and multilevel regression models. Results: The resulting General Practice Clinical Linkages Interview (GP-CLI is a nine-item tool with three underlying factors: referral and advice linkages, shared care and care planning linkages, and community access and awareness linkages. Local availability of chronic disease services has no affect on the comprehensiveness of services with which practices link, however comprehensiveness of clinical linkages has an association with patient assessment of access, receptionist services, and of continuity of care in their general practice. Conclusions: The GP-CLI may be useful to researchers examining comparable health care systems for measuring the comprehensiveness and quality of linkages at a general practice-level with related services, possessing both internal and external validity. The tool can be used with large samples

  20. Faculty Demand in Higher Education

    Science.gov (United States)

    Rosenthal, Danielle

    2007-01-01

    The objective of this study is to identify the factors that shift the demand curve for faculty at not-for-profit private institutions. It is unique in that to the author's knowledge no other study has directly addressed the question of how the positive correlation between average faculty salaries and faculty-student ratios can be reconciled with…

  1. 农村消费需求的制约因素分析%Analysis of Restraint Factors on Rural Consumer Demand

    Institute of Scientific and Technical Information of China (English)

    练绪宁

    2014-01-01

    It is important to expand rural consumer demand in promoting economic growth. The increasing farmers' income, the unsound market order and guarantee system, as well as the consumer credit constraint restrict the development of rural consumer demand. Therefore, we should enhance rural income, accelerate infrastructure con-struction, improve the market system and guarantee the system and popularize rural credits to expand consumer de-mand and promote the sustained and stable development in the economy in China.%扩大农村消费需求是推动经济增长的重要环节,但农民增收难度大、市场秩序和保障制度不健全、消费信贷约束等因素制约着我国农村消费需求发展。需要通过提高农村收入、加快基础设施建设、完善市场体系和保障制度、普及农村信贷等途径扩大我国农村消费需求,促进我国经济持续稳定发展。

  2. Consumer risk perceptions toward agricultural biotechnology, self-protection, and food demand: the case of milk in the United States.

    Science.gov (United States)

    Zepeda, Lydia; Douthitt, Robin; You, So-Ye

    2003-10-01

    This study is an econometric systems approach to modeling the factors and linkages affecting risk perceptions toward agricultural biotechnology, self-protection actions, and food demand. This model is applied to milk in the United States, but it can be adapted to other products as well as other categories of risk perceptions. The contribution of this formulation is the ability to examine how explanatory factors influence risk perceptions and whether they translate into behavior and ultimately what impact this has on aggregate markets. Hadden's outrage factors on heightening risk perceptions are among the factors examined. In particular, the article examines the role of labeling as a means of permitting informed consent to mitigate outrage factors. The effects of attitudinal, economic, and demographic factors on risk perceptions are also explored, as well as the linkage between risk perceptions, consumer behavior, and food demand. Because risk perceptions and self-protection actions are categorical variables and demand is a continuous variable, the model is estimated as a two-stage mixed system with a covariance correction procedure suggested by Amemiya. The findings indicate that it is the availability of labeling, not the price difference, between that labeled milk and milk produced with recombinant bovine Somatotropin (rbST) that significantly affects consumer's selection of rbST-free milk. The results indicate that greater availability of labeled milk would not only significantly increase the proportion of consumers who purchased labeled milk, its availability would also reduce the perception of risk associated with rbST, whether consumers purchase it or not. In other words, availability of rbST-free milk translates into lower risk perceptions toward milk produced with rbST.

  3. Directed Graphs, Decompositions, and Spatial Linkages

    CERN Document Server

    Shai, Offer; Whiteley, Walter

    2010-01-01

    The decomposition of a system of constraints into small basic components is an important tool of design and analysis. Specifically, the decomposition of a linkage into minimal components is a central tool of analysis and synthesis of linkages. In this paper we prove that every pinned 3-isostatic (minimally rigid) graph (grounded linkage) has a unique decomposition into minimal strongly connected components (in the sense of directed graphs) which we call 3-Assur graphs. This analysis extends the Assur decompositions of plane linkages previously studied in the mathematical and the mechanical engineering literature. These 3-Assur graphs are the central building blocks for all kinematic linkages in 3-space. They share a number of key combinatorial and geometric properties with the 2-Assur graphs, including an associated lower block-triangular decomposition of the pinned rigidity matrix which provides a format for extending the motion induced by inserting one driver in a bottom Assur linkage to the joints of the e...

  4. 企业间协调联动机制影响因素分析——基于结构方程模型的分析%Analysis on Influential Factors of the Coordination and Linkage Mechanism Between Enterprises—Based on the SEM

    Institute of Scientific and Technical Information of China (English)

    徐娜; 王锐; 王辉

    2012-01-01

    Affected by multiple factors,the coordination and linkage mechanism shows characteristics of diversity and complexity.This paper puts forwords six key factors:interdependence and trust,uncertainty,enterprise culture,information communication and sharing,benefit-sharing,policy and legal environment.Using the structural equation model,through an analysis of the complex interactions of different factors on the pathway and the linkage between factors,the corresponding countermeasures are proposed to improve the cooperative relationship.%企业间协调联动机制受多因素综合影响,体现出多元化与复杂性特征。利用结构方程模型,针对影响协调联动机制的6个关键因素:相互依赖与信任、不确定性、企业文化、信息沟通与共享、利益分享和政策法律环境,分析验证不同因素对协调联动的作用路径及各因素间的复杂交互关系,并提出改进合作关系的相应对策。

  5. Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height.

    Science.gov (United States)

    Hirschhorn, J N; Lindgren, C M; Daly, M J; Kirby, A; Schaffner, S F; Burtt, N P; Altshuler, D; Parker, A; Rioux, J D; Platko, J; Gaudet, D; Hudson, T J; Groop, L C; Lander, E S

    2001-07-01

    Genomewide linkage analysis has been extremely successful at identification of the genetic variation underlying single-gene disorders. However, linkage analysis has been less successful for common human diseases and other complex traits in which multiple genetic and environmental factors interact to influence disease risk. We hypothesized that a highly heritable complex trait, in which the contribution of environmental factors was relatively limited, might be more amenable to linkage analysis. We therefore chose to study stature (adult height), for which heritability is approximately 75%-90% (Phillips and Matheny 1990; Carmichael and McGue 1995; Preece 1996; Silventoinen et al. 2000). We reanalyzed genomewide scans from four populations for which genotype and height data were available, using a variance-components method implemented in GENEHUNTER 2.0 (Pratt et al. 2000). The populations consisted of 408 individuals in 58 families from the Botnia region of Finland, 753 individuals in 183 families from other parts of Finland, 746 individuals in 179 families from Southern Sweden, and 420 individuals in 63 families from the Saguenay-Lac-St.-Jean region of Quebec. Four regions showed evidence of linkage to stature: 6q24-25, multipoint LOD score 3.85 at marker D6S1007 in Botnia (genomewide Pgenetically tractable and provide insight into the genetic architecture of complex traits.

  6. Determining Demand for Help-Wanted Advertising

    OpenAIRE

    Sherrer, Mary T.

    2002-01-01

    The purpose of this thesis is to investigate how the price of advertising space affects the demand for help-wanted advertising. To do so, this thesis develops and estimates an econometric model to explain and predict the demand for help-wanted advertising placed in a newspaper. For the most part, economic theory and the literature suggest that basic economic and demographic factors explain the demand for help-wanted advertising. The literature and empirical studies confirm an inverse relatio...

  7. The Market Demand for Air Transportation

    Science.gov (United States)

    Taneja, N.

    1972-01-01

    Although the presentation will touch upon the areas of market for air transportation, the theoretical foundations of the demand function, the demand models, and model selection and evaluation, the emphasis of the presentation will be on a qualitative description of the factors affecting the demand for air transportation. The presentation will rely heavily on the results of market surveys carried out by the Port of New York Authority, the University of Michigan, and Census of Transportation.

  8. The Community Health Care Demands Status and Its Influencing Factors of Elderly in Xi anni ng Ci ty%咸宁市城区老年人社区护理需求及其影响因素分析

    Institute of Scientific and Technical Information of China (English)

    张志霞; 罗菊英; 汪娟; 叶艳胜; 孔令磷

    2016-01-01

    Objectives To investigate community health care demands status and its influencing factors of elderly in Xianning City and to provide scientific reference for better community nursing services.Methods A self-designed community health care demand questionnaire was used to analyze the current status of community health care de-mands for 294 elderly in Xianning city.Results The total score of community health care demands of the elderly in Xianning was 2.89 ± 0.82. The demand of health prevention was the highest ,while the demand of disease nursing was the lowest.Multiple linear regression analysis showed that demand of disease nursing(β′=0.131) ,health pre-vention(β′=0.152) ,and overall community health nursing(β′=0.178)for elderly with higher educational level were higher than elderly with lower educational level(P<0.05). The elderly who were married showed more demand of health prevention than the elderly who were unmarried ,divorced or widowed(β′=0.154 ,P<0.05). The demand of health promotion for the younger elderly(β′= -0.128)and elderly with higher economic level(β′= 0.163)were higher than the older elderly and elderly with low economic level(P<0.05).Conclusions The elderly showed higher demands of health promotion.Community health care services should be made according to the demands of the elderly.%目的:探讨咸宁市城区老年人社区护理需求及影响因素。方法采用自制社区护理需求问卷对咸宁市城区294名老年人进行问卷调查。结果咸宁市城区老年人的社区护理总需求得分为2.89±0.82分,疾病预防需求最高,疾病护理需求最低。多元线性回归分析显示,文化程度较高者疾病护理(β′=0.131)、疾病预防(β′=0.152)和社区护理总需求(β′=0.178)得分高于文化程度较低者(P<0.05);有配偶者疾病预防得分高于未婚/离异/丧偶者(β′=0.154,P<0.05);经济收入较高(β′=0.163

  9. PERFECT DEMAND ILLUSION

    Directory of Open Access Journals (Sweden)

    Alexander Yu. Sulimov

    2015-01-01

    Full Text Available The article is devoted to technique «Perfect demand illusion», which allows to strengthen the competitive advantageof retailers. Also in the paper spells out the golden rules of visual merchandising.The definition of the method «Demand illusion», formulated the conditions of its functioning, and is determined by the mainhypothesis of the existence of this method.Furthermore, given the definition of the «Perfect demand illusion», and describes its additional conditions. Also spells out the advantages of the «Perfect demandillusion», before the «Demand illusion».

  10. Divers of Passenger Demand

    OpenAIRE

    Wittmer, Andreas

    2011-01-01

    -Overview drivers of passenger demand -Driver 1: Economic growth in developing countries -Driver 2: International business travel in developed countries -Driver 3: International leisure travel in developed countries

  11. Linkages between NAMA - LEDS - MRV

    DEFF Research Database (Denmark)

    Agyemang-Bonsu, William; Benioff, Ron; Cox, Sadie

    Low Emission Development Strategies (LEDS), Nationally Appropriate Mitigation Actions (NAMAs) and Monitoring, Reporting and Verification (MRV) are three of the key conceptual components emerging as part of the global architecture for a new climate agreement by 2015. The three components are devel......Low Emission Development Strategies (LEDS), Nationally Appropriate Mitigation Actions (NAMAs) and Monitoring, Reporting and Verification (MRV) are three of the key conceptual components emerging as part of the global architecture for a new climate agreement by 2015. The three components...... how the three components are conceptually interlinked. Identifying the linkages can inform the work on each component and strengthen coordination of work in the context of the three big partnerships; the International Partnership on Mitigation and MRV, the LEDS Global Partnership and the NAMA...

  12. Influence of College Students' Psychological Problems in Prevention and Intervention of Linkage Mechanism Construction Factors%大学生心理预防与干预联动的构建

    Institute of Scientific and Technical Information of China (English)

    赵芸

    2011-01-01

    The formation of college students' psychological problems is not effective prevention and intervention of the linkage mechanism, the main reason is various departments of the College students" psychological health education, lack of awareness of the importance of linkage mechanism of main force inadequacy and psychology of lack of expertise and the levels of psychological health education network organization structure of the unclear responsibility, and short of working enthusiasm.%目前高校没有形成大学生心理问题预防与干预的有效联动机制,主要原因是各级部门对大学生心理健康教育的重要性认识不足、联动机制中的主体力量不足,缺乏心理学专业知识,各级心理健康教育网络组织结构的职责不明确,工作积极性欠缺,对此,作者进行了思考,提出了解决的对策。

  13. Occupational physical demand and risk of hip fracture in older women.

    Science.gov (United States)

    Palumbo, Aimee J; Michael, Yvonne L; Burstyn, Igor; Lee, Brian K; Wallace, Robert

    2015-08-01

    Hip fractures are leading causes of disability, morbidity and mortality among older women. Since physical activity helps maintain physical functioning and bone mineral density, occupational physical demand may influence fracture risk. This study investigates the association of occupational physical demand with hip fracture incidence among women. The Women's Health Initiative Observational Study is a multiethnic cohort of 93,676 postmenopausal women, 50-79 years of age at enrolment, enrolled from 1994 to 1998 at 40 geographically diverse clinical centres throughout the USA. Outcomes including hip fractures were assessed annually and up to 3 jobs held since age 18 years were reported by each woman. Occupational physical demand levels were assigned for each job through linkage of occupational titles with Standard Occupational Codes and the Occupational Information Network. Average, cumulative and peak physical demand scores both before and after menopause and throughout women's work life were estimated. Women were followed through 2010 for an average of 11.5 years; 1834 hip fractures occurred during this time. We did not observe an overall association of occupational physical demand with subsequent risk of hip fracture after adjusting for age, race/ethnicity, birth region and education. Previous research on occupations and hip fracture risk in women is inconclusive. This study was able to take critical risk periods into account and control for confounding factors in a large cohort of older women to show that overall occupational physical demand neither increases nor decreases risk of hip fracture later in life. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  14. Extent of linkage disequilibrium in chicken

    NARCIS (Netherlands)

    Aerts, J.; Megens, H.J.W.C.; Veenendaal, T.; Ovcharenko, I.; Crooijmans, R.P.M.A.; Gordon, L.; Stubbs, L.; Groenen, M.A.M.; Rodoinov, A.; Gaginskaya, E.

    2007-01-01

    Many of the economically important traits in chicken are multifactorial and governed by multiple genes located at different quantitative trait loci (QTLs). The optimal marker density to identify these QTLs in linkage and association studies is largely determined by the extent of linkage

  15. Chemical oxygen demand removal efficiency and limited factors study of aminosilicone polymers in a water emulsion by iron-carbon micro-electrolysis.

    Science.gov (United States)

    Yang, Shangyuan; Liang, Zhiwei; Yu, Huadong; Wang, Yunlong; Chen, Yingxu

    2014-02-01

    Micro-electrolysis was applied in the present study to investigate the effect of pH, iron-carbon mass ratio, contact time, and treatment batch on the removal efficiency of chemical oxygen demand (COD) within an aminosilicone emulsion. The results exhibited that the removal efficiency of COD decreased linearly with the batch increase, and this tendency was consistent under the various conditions. The adsorption of activated carbons contributes a large portion to the elimination of COD within the aminosilicone emulsion. The oxidation action of iron-carbon micro-electrolysis was proven and the aminosilicone emulsion's COD removal contribution was approximately 16%. Aminosilicone polymers were adsorbed on the surface of activated carbons and iron chips, which contributes to the decline of COD removal efficiency and limits the contribution of oxidation action.

  16. Prospects for European labour demand.

    Science.gov (United States)

    Lindley, R M

    1988-07-01

    The impact of economic and technological trends upon the level and structure of labor demand is examined, exploring the methods used to model the labor market and making special reference to demography and technology. Evidence on recent and prospective changes in labor demand is reviewed for France, Germany, Italy, the Netherlands, and the UK. The models used to explore future employment scenarios usually fail to incorporate the linkages required to fully analyze the various demographic-economic interactions. Further, this is not generally viewed as a limitation, given the time frame of most employment projections and their preoccupation with changes in the structure of labor demand. Medium-term multisectoral models tend to pay more attention to both demographic and technical change, but the treatment of both aspects is limited. The projections provide a framework for considering how both socioeconomic behavior and policy might change to achieve different outcomes. The greater a model's behavioral content, as expressed in its relationships between different variables, the greater the insight obtainable from simulation exercises. The 1st half of the 1970s was characterized by a reduction in German employment, representing the severest of European reactions to the oil crisis. The 2nd half of the decade recorded rapid growth in Italy and the Netherlands. The 1980s started with marked declines in Germany and the UK. Overall, the net gains of the 1970s were lost in the recession following the 2nd oil crisis. In none of the 5 countries studied does any realistic prospect emerge of achieving full employment before 2000. The most optimistic outcome is that unemployment will decline only slowly, it at all. The growth of both new forms and areas of employment will not compensate sufficiently for the loss of jobs elsewhere and the growth of labor supply. The industrial sector will continue to experience change in favor of the service sector but at a slower rate than during

  17. Paramedic Physical Demands Analysis

    Science.gov (United States)

    2014-07-01

    medical bags, cardiac monitor, stretcher, stair chair, etc.) were not standardized across services. As a result the total amount of equipment weight ...report describes the pushing/pulling, walking, and stair climbing demands as observed during the observation periods. Walking demands varied between the...standard deviation about the mean. .................................................................. 25 Figure 7 - The maximum weight (heaviest patient

  18. Wood supply and demand

    Science.gov (United States)

    Peter J. Ince; David B. McKeever

    2011-01-01

    At times in history, there have been concerns that demand for wood (timber) would be greater than the ability to supply it, but that concern has recently dissipated. The wood supply and demand situation has changed because of market transitions, economic downturns, and continued forest growth. This article provides a concise overview of this change as it relates to the...

  19. Grey Correlation Analysis on Factors Affecting Chinese Farmers' Health Insurance Demands%中国农民健康保险需求影响因素的灰色关联分析

    Institute of Scientific and Technical Information of China (English)

    彭晓博; 孙祁祥

    2012-01-01

    Rural residents' medical expenditure will increase notably as the surge in the elderly population. There- fore it will lead to a heavy burden on government's budget if the increase in healthcare expenditure was solely born by the government. The authors suggested, as a consequence, the importance of developing a multi-pillar health insurance system ,which should include government subsidized health insurance as well as commercial health insurance, should be recognized. The authors analyzed three factors which were hypothesized to be correlated with farmers' healthcare demands ,which included economic factors ,healthcare resource factors as well as social and cultural factors. Using a number of variables measuringthe above three factors, the authors conducted a Grey Relation Analysis. The results showed that farmers' health insurance demand was significantly correlated with economic factors , as well as healthcare resource factor.%随着老年人口增多,农村医疗支出也会增加。未来若单靠政府投入势必会带来沉重的财政支出负担,长期将难以持续。基于这一背景,作者认为应当大力发展商业健康保险,培育市场,尽快建立起多支柱的医疗保障体系。本文从需求角度出发,认为影响农民健康保险需求的因素主要包括经济、卫生资源和社会文化等因素,并采用三因素中的代表性变量进行灰色关联分析,结果显示,卫生资源和支付能力与健康保险需求具有较强的灰色关联度。

  20. Causality in demand

    DEFF Research Database (Denmark)

    Nielsen, Max; Jensen, Frank; Setälä, Jari;

    2011-01-01

    This article focuses on causality in demand. A methodology where causality is imposed and tested within an empirical co-integrated demand model, not prespecified, is suggested. The methodology allows different causality of different products within the same demand system. The methodology is applied...... to fish demand. On the German market for farmed trout and substitutes, it is found that supply sources, i.e. aquaculture and fishery, are not the only determinant of causality. Storing, tightness of management and aggregation level of integrated markets might also be important. The methodological...... implication is that more explicit focus on causality in demand analyses provides improved information. The results suggest that frozen trout forms part of a large European whitefish market, where prices of fresh trout are formed on a relatively separate market. Redfish is a substitute on both markets...

  1. Analysis of Influencing Factors on South Korea Tourists Demands for China Based on Double Logarithmic Model%基于双对数模型的人境韩国游客旅游需求影响因素分析

    Institute of Scientific and Technical Information of China (English)

    赵陶钧; 杨丽琼; 和亚君

    2012-01-01

    South Korea is one of the main tourist countries in China' s inbound market, and therefore it is of important significance to research influencing factors of South Korea tourist demand for China. By using the double logarithmic model and SPSS20 tool to analyse the data, this article makes a conclusion that the ratio of consumer price index (CPI) of both South Korea and China, per capita GDP of South Korea and SARS event are the main factors which influence the South Korea tourist demands for China, while the exchange rate of Won against RMB, the finance crisis of Southeast Asia and the finance crisis of the world don' t have the significant impacts on demand. Among these factors, the ratio of CPI of both South Korea and China, per capita GDP of South Korea and exchange rate of Won against RMB have positive correlation with South Korea tourist demand for China, while other factors have negative correlation with it. During the analysis, the article puts forward the view that a factor With insignificant ' t' test should not be removed from the model under certain conditions, and also explores the methods of choosing data.%借助双对数模型,使用SPSS20软件得出了对韩国游客旅华需求影响的主要因素有韩国与中国相对CPI、韩国人均GDP以及非典事件,而韩元兑人民币汇率、亚洲金融危机、全球金融危机对需求的影响不显著,其中对需求的作用为正相关的因素有韩国与中国相对CPI、韩国人均GDP以及韩元兑人民币汇率,其余因素表现为负相关作用。分析过程中提出了在符合一定条件的前提下不应将没有通过t检验的因素从模型中剔除的看法,同时对数据的选择进行了探索。

  2. Factors of Demand for Dalian Public Rental Housing%大连公租房需求方影响因素调查研究

    Institute of Scientific and Technical Information of China (English)

    邢燕婷; 宋永发

    2013-01-01

      The first public rental housing of partial city has already stepped in distribution phase with the phenomenon of deserted vacancy. In order to promote benign docking between demand for and supply of Dalian public rental housing,the paper takes Dalian Quanshui public housing which is about to enter the lottery stage as an example,and uses questionnaire survey on the attitude and confidence of the public rental housing from the potential demanders for housing. The questionnaire results are analyzed based on testing of validity and reliability. The results indicate that the public currently is lacking confidence and acceptance with a grain of salt about public rental housing security system. Finally,the article puts forward five proposals to improve the Dalian public rental housing system:Guiding the concept of residential housing consumption correctly,encouraging social forces to participate in raising public rental housing,establishing scientific and reasonable rent,relieving the household registration restriction and improving the mechanism of management.%  针对部分城市首批公租房在配租阶段出现的冷清空置现象,为促使大连公租房供需之间实现良性对接,以即将进入摇号阶段的泉水公租房为例,通过问卷形式调查大连市潜在住房需求者对公租房的态度和信心情况。在问卷效度和信度检验的基础上,对问卷结果进行分析,结果显示,当前市民对公租房保障体系信心不足。针对大连市公租房建设和实施现状提出正确引导居民住房消费观念、鼓励社会力量参与筹集公租房房源、制定科学合理的租金、放宽户籍门槛以及完善管理机制等建议。

  3. Demand and influencing factors analysis of home care for discharged patients%太原市出院患者居家护理需求及影响因素分析

    Institute of Scientific and Technical Information of China (English)

    石贞仙; 田艳妮

    2015-01-01

    目的:探讨出院患者的居家护理需求及其影响因素。方法采用自设问卷对太原市3所三级甲等综合医院的450例有不同居家护理需求的出院患者进行调查;采用均数±标准差( x± s)、百分比(%)进行统计学描述,采用t检验、方差分析、多元线性回归进行统计学分析。结果出院患者护理需求均分为(2.47±0.96)分,需求强度健康指导、康复护理、心理护理、临床护理、生活护理分别为(2.85±1.25),(2.75±1.64),(2.58±1.68),(2.46±1.17),(1.85±1.03)分;多元线性回归分析显示,患病种类和收入水平是居家护理需求的正性影响因素;ADL得分和婚姻状况是居家护理需求的负性影响因素。结论居家护理是未来护理的发展方向,应以需求为导向,从多角度出发,制定针对性的对策,开展适合国情的居家护理,满足多元化需求。%Objective To explore the demand and influencing factors analysis of home care for discharged patients. Methods The self-designed questionnaire was used to investigated 450 patients discharged from three level three class A hospitals in Taiyuan; we utilized (x± s), (%) to statistically describe, and applied t test, variance analysis and multiple linear regression for statistically analysis. Results The average demand score of nursing care was (2. 47 ± 0. 96) in discharged patients, while the score of demand degree of health guidance, rehabilitation nursing, psychological nursing, clinical nursing and life care were ( 2. 85 ± 1. 25), (2. 75 ± 1. 64), (2. 58 ± 1. 68), (2. 46 ± 1. 17) and (1. 85 ± 1. 03) respectively; multi liner regression analysis represented that the type of patients and income were the positive influencing factors for the demand of home care;the score of ADL and marriage status were the negative influencing factors for home care demand. Conclusions Home care is one direction of nursing development in future, so it should guide by

  4. Evidence for an asthma risk locus on chromosome Xp: a replication linkage study

    DEFF Research Database (Denmark)

    Brasch-Andersen, C; Møller, M U; Haagerup, A;

    2008-01-01

    BACKGROUND: Asthma is a complex genetic disorder characterized by chronic inflammation in the airways. Identification of genetic risk factors for asthma has been complicated due to genetic heterogeneity and influence from environmental risk factors. Despite the fact that multiple genetic linkage...... studies have been carried out the results are still conflicting and call for replication experiments. A Danish genome-wide scan has prior reported evidence for candidate regions for asthma susceptibility genes on chromosomes 1p, 5q, 6p, 12q and Xp. Linkage to chromosome 12q was later confirmed in the same...... replication sample as used in the present study. The aim of the study was to replicate linkage to candidate regions for asthma in an independent Danish sample. METHODS: We performed a replication study investigating linkage to candidate regions for asthma on chromosomes 1p36.31-p36.21, 5q15-q23.2, 6p24.3-p22...

  5. The REBUS-MCNP linkage.

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, J. G.; Nuclear Engineering Division

    2009-04-24

    The Reduced Enrichment Research and Test Reactor (RERTR) Program uses the REBUS-PC computer code to provide reactor physics and core design information such as neutron flux distributions in space, energy, and time, and to track isotopic changes in fuel and neutron absorbers with burnup. REBUS-PC models the complete fuel cycle including shuffling capability. REBUS-PC evolved using the neutronic capabilities of multi-group diffusion theory code DIF3D 9.0, but was extended to apply the continuous energy Monte Carlo code MCNP for one-group fluxes and cross-sections. The linkage between REBUS-PC and MCNP has recently been modernized and extended, as described in this manual. REBUS-PC now calls MCNP via a system call so that the user can apply any valid MCNP executable. The interface between REBUS-PC and MCNP requires minimal changes to an existing MCNP model, and little additional input. The REBUS-MCNP interface can also be used in conjunction with DIF3D neutronics to update an MCNP model with fuel compositions predicted using a DIF3D based depletion.

  6. Gastos em saúde: os fatores que agem na demanda e na oferta dos serviços de saúde Health expenditures: demand and supplly factors in health services

    Directory of Open Access Journals (Sweden)

    Paola Zucchi

    2000-12-01

    Full Text Available Neste momento de crise financeira do Estado, é importante o uso adequado dos recursos econômicos disponíveis, e este trabalho objetiva estudar os fatores que determinam o aumento dos gastos em saúde; é uma revisão crítica do tema, com um levantamento sistemático das publicações dos últimos dez anos, considerando-se os principais estudiosos da disciplina da economia da saúde no Brasil e de outros países. Os fatores que agem na demanda por serviços de saúde são de natureza variada, podendo se sobrepor, o que aumenta ainda mais a demanda: necessidade sentida, fatores psicossociais, seguridade social, demografía, epidemiología, utilização dos serviços, regulamentação e fatores culturais. Os que agem na oferta da assistência à saúde são: progresso técnico-médico, difusão da inovação e multiplicação dos centros de assistência à saúde. Os fatores da demanda não podem ser rapidamente contidos, enquanto que os de oferta são muito mais facilmentecontrolados, mas são poucos os exemplos encontrados na literatura sobre o sucesso das medidas de controle.In this moment of financial crisis of the State, it is important to adequately use the economic resources available. The objective of this survey is to study the factors that determine the increase in health expenditures. It is a critical review of the subject, conducting a systematic survey of publications for the past ten years, and considering the main scholars in health economics in Brazil and other countries. The health service demand factors have varied features, and may be overlapping, thus increasing even more the demand: the perceived need, social security, demography, epidemiology, the use of services, regulation, psychosocial and cultural factors. The health service supply factors are technical-medical progress, promotion of innovations and multiplication of health care centers. Demand factors cannot be quickly curbed, whereas the supply factors are more

  7. DYNAMIC DESIGN OF VARIABLE SPEED PLANAR LINKAGES

    Institute of Scientific and Technical Information of China (English)

    Yao Yanan; Yan Hongsen; Zou Huijun

    2005-01-01

    A method for improving dynamic characteristics of planar linkages by actively varying the speed function of the input link is presented. Design criteria and constraints for the dynamic design of variable speed planar linkages are developed. Both analytical and optimization approaches for determining suitable input speed functions to minimize the driving torque, the shaking moment, or both simultaneously of planar linkages, subject to various design requirements and constraints, are derived.Finally, some examples are given to illustrate the design procedure and to verify its feasibility.

  8. Domestic Demand Will Work

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    China can invigorate its economy by expanding domestic demand and boosting consumption chinese bankers are preparing to set up finance companies that provide consumer loans in major cities like Beijing and Shanghai.

  9. Intelligent energy demand forecasting

    CERN Document Server

    Hong, Wei-Chiang

    2013-01-01

    This book offers approaches and methods to calculate optimal electric energy allocation, using evolutionary algorithms and intelligent analytical tools to improve the accuracy of demand forecasting. Focuses on improving the drawbacks of existing algorithms.

  10. Household fuel demand analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S.; Hirst, E.; Jackson, J.

    1976-01-01

    This study develops econometric models of residential demands for electricity, natural gas, and petroleum products. Fuel demands per household are estimated as functions of fuel prices, per capita income, heating degree days, and mean July temperature. Cross-sectional models are developed using a large data base containing observations for each state and year from 1951 through 1974. Long-run own-price elasticities for all three fuels are greater than unity with natural gas showing the greatest sensitivity to own-price changes. Cross-price elasticities are all less than unity except for the elasticity of demand for oil with respect to the price of gas (which is even larger than the own-price elasticity of demand for oil). The models show considerable stabiity with respect to own-price elasticities but much instability with respect to the cross-price and income elasticities.

  11. Impact of Energy Demands

    Science.gov (United States)

    Cambel, Ali B.

    1970-01-01

    The types of pollutants associated with the process of power production are identified. A nine-point proposal is presented on the ways the increase in power demands might be achieved with the minimum threat to the environment. (PR)

  12. Overview of economic, legal, and water availability factors affecting the demand for dry and wet/dry cooling for thermal power plants

    Energy Technology Data Exchange (ETDEWEB)

    Hendrickson, P.L.

    1977-06-01

    The economic, legal, and water availability factors which will contribute to selection in the future, of dry and wet/dry cooling vis-a-vis other methods of cooling and which will influence the projected market for these types of cooling systems in the next twenty years are considered.

  13. A COMPARISON BETWEEN SINGLE LINKAGE AND COMPLETE LINKAGE IN AGGLOMERATIVE HIERARCHICAL CLUSTER ANALYSIS FOR IDENTIFYING TOURISTS SEGMENTS

    OpenAIRE

    Noor Rashidah Rashid

    2012-01-01

    Cluster Analysis is a multivariate method in statistics. Agglomerative Hierarchical Cluster Analysis is one of approaches in Cluster Analysis. There are two linkage methods in Agglomerative Hierarchical Cluster Analysis which are Single Linkage and Complete Linkage. The purpose of this study is to compare between Single Linkage and Complete Linkage in Agglomerative Hierarchical Cluster Analysis. The comparison of performances between these linkage methods was shown by using Kruskal-Wallis tes...

  14. Perioperative Health Education Demands of Patients Undergoing Renal Transplantation and Its Influencing Factors%肾移植患者围术期健康教育需求调查及影响因素分析

    Institute of Scientific and Technical Information of China (English)

    刘佳; 严谨; 阳玲; 周丽琴

    2011-01-01

    目的 了解肾移植患者围术期的健康教育需求及其变化趋势,探讨影响其健康教育需求的相关因素.方法 自制肾移植患者围术期健康教育需求调查表,对围术期肾移植患者分别在入院后第1天、术前1 d、术后第5天、出院前1 d共4个时间点进行健康教育需求调查.结果 患者围术期不同时间点健康教育需求有所不同,但排斥反应的早期表现、手术后哪些食物绝对不能吃、感染的早期表现、手术后总的饮食要求及出院后哪些情况需要立即就诊5项是患者整个围术期都需求较为强烈的内容;患者围术期不同时间点健康教育需求与其年龄、婚姻状况、等待肾移植时问、移植方式以及家庭月收入等相关.结论 肾移植患者围术期不同时间点健康教育需求不同,多种个体化因素如等待肾移植时间、家庭月收入、婚姻状况和移植方式等影响患者的健康教育需求.%Objective To understand health education demand in perioperative patients with renal transplantation, and to explore its influencing factors. Methods The survey was conducted on the 1st day after admission, the day before operation, the 5th day after operation and the day before discharge respectively with a self-designed health education demand questionnaire. Results There were different health education demands at different time and items including clinical symptoms of early rejection after surgery, the early manifestations of infection, the overall dietary requirements and the situation requiring seeing a doctor after discharge listed on the top 10 of health education demands at four stages of perioperative renal transplantation. There were significant relationships among health education demands, age, marital status, waiting time for transplantation, transplant-related patterns and family income. Conclusion The perioperative patients of renal transplantation present different health education demand at four

  15. Expected Demand for the U.S. Navy to Serve as an Instrument of U.S. Foreign Policy: Thinking About Political and Military Environmental Factors.

    Science.gov (United States)

    1980-04-01

    Military Budgets. Coile, Russell C., "A Bibliometric Examination of Francis P. Hoeber and William Schneider, Jr. (eds.) the Sqpuare Root Theory of...naval power for political purposes over the last 35 years. Although land-based aviation can have a major combat impact , including on the struggle to use...prevent his utter defeat and subjugation). In such cases, iThese generalizations about the factors affecting the impact of the superpowers on Third

  16. Linkage disequilibrium in wild mice.

    Directory of Open Access Journals (Sweden)

    Cathy C Laurie

    2007-08-01

    Full Text Available Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of these loci have been detected, but only a small number of the underlying causative genes have been identified. The main difficulty is the extensive linkage disequilibrium (LD in intercross progeny and the slow process of fine-scale mapping by traditional methods. Recently, new approaches have been introduced, such as association studies with inbred lines and multigenerational crosses. These approaches are very useful for interval reduction, but generally do not provide single-gene resolution because of strong LD extending over one to several megabases. Here, we investigate the genetic structure of a natural population of mice in Arizona to determine its suitability for fine-scale LD mapping and association studies. There are three main findings: (1 Arizona mice have a high level of genetic variation, which includes a large fraction of the sequence variation present in classical strains of laboratory mice; (2 they show clear evidence of local inbreeding but appear to lack stable population structure across the study area; and (3 LD decays with distance at a rate similar to human populations, which is considerably more rapid than in laboratory populations of mice. Strong associations in Arizona mice are limited primarily to markers less than 100 kb apart, which provides the possibility of fine-scale association mapping at the level of one or a few genes. Although other considerations, such as sample size requirements and marker discovery, are serious issues in the implementation of association studies, the genetic variation and LD results indicate that wild mice could provide a useful tool for identifying genes that cause variation in complex traits.

  17. [Dystroglycan linkage and muscular dystrophy].

    Science.gov (United States)

    Shimizu, Teruo

    2002-11-01

    Dystroglycan is a key complex between basal lamina laminin, extracellularly and membrano-cytoskeleton, intracellularly. The damage of this linkage is turned out to cause muscular dystrophies. Dystroglycan knockout is lethal. Dystroglycan-associated intracellular proteins such as dystrophin, dystrobrevin, sarcoglycans, plectin and caveolin-3 are responsible for causing severe (Duchenne type) and moderate forms (Becker, LGMDs). Laminin, dystroglycan-binding extracellular protein, is deficient in the most severe form of congenital muscular dystrophy with normal intelligence and eye. Recently, a remarkable progress is made in most severe forms of congenital muscular dystrophy with anomalies of brain and eye such as Fukuyama type (Japan) and muscle-eye-brain disease (Finland). The gene product for Fukuyama type, fukutin, belongs to a family of glycosylation enzymes in bacteria and yeast. Since alpha-dystroglycan contains 14-15 o-glycans, ser/thr-mannose 2-1 GlcNAc 4-1 Gal 3-2 Sial in the middle third mucin-domain and the sial-o-glycan is essential for laminin-binding, and since alpha-dystroglycan is defective in Fukuyama type sarcolemma with anti both sugar moiety- and peptide-antidodies, defective fukutin causes incomplete o-glycosylation of alpha-dystroglycan. In '02, it is clarified that a glycosylation enzyme, POMGnT1 which modifies GlcNAc onto ser/thr-mannose, is defective in 6 MEB patients. The loss of the enzyme activity is turned out to lose alpha-dystroglycan from sarcolemma of MEB. These data strongly suggests that o-glycosylation defect of alpha-dystroglycan causes the most severe congenital muscular dystrophy such as Fukuyama type, MEB and Walker Warburg syndrome.

  18. An estimating function approach to linkage heterogeneity

    Indian Academy of Sciences (India)

    He Gao; Ying Zhou; Weijun Ma; Haidong Liu; Linan Zhao

    2013-12-01

    Testing linkage heterogeneity between two loci is an important issue in genetics. Currently, there are four methods (K-test, A-test, B-test and D-test) for testing linkage heterogeneity in linkage analysis, which are based on the likelihood-ratio test. Among them, the commonly used methods are the K-test and A-test. In this paper, we present a novel test method which is different from the above four tests, called G-test. The new test statistic is based on estimating function, possessing a theoretic asymptotic distribution, and therefore demonstrates its own advantages. The proposed test is applied to analyse a real pedigree dataset. Our simulation results also indicate that the G-test performs well in terms of power of testing linkage heterogeneity and outperforms the current methods to some degree.

  19. Missing Linkages in California's Landscape [ds420

    Data.gov (United States)

    California Department of Resources — The critical need for conserving landscape linkages first came to the forefront of conservation thinking in California in November 2000, when a statewide interagency...

  20. Connectivity and Linkages Between Isolated Habitat

    Data.gov (United States)

    California Department of Resources — Proposed areas where connectiviy and linkages between isolated habitat on the San Joaquin Valley floor and natural lands in the surrounding foothills should be...

  1. Linkage analysis of quantitative refraction and refractive errors in the Beaver Dam Eye Study.

    Science.gov (United States)

    Klein, Alison P; Duggal, Priya; Lee, Kristine E; Cheng, Ching-Yu; Klein, Ronald; Bailey-Wilson, Joan E; Klein, Barbara E K

    2011-07-13

    Refraction, as measured by spherical equivalent, is the need for an external lens to focus images on the retina. While genetic factors play an important role in the development of refractive errors, few susceptibility genes have been identified. However, several regions of linkage have been reported for myopia (2q, 4q, 7q, 12q, 17q, 18p, 22q, and Xq) and for quantitative refraction (1p, 3q, 4q, 7p, 8p, and 11p). To replicate previously identified linkage peaks and to identify novel loci that influence quantitative refraction and refractive errors, linkage analysis of spherical equivalent, myopia, and hyperopia in the Beaver Dam Eye Study was performed. Nonparametric, sibling-pair, genome-wide linkage analyses of refraction (spherical equivalent adjusted for age, education, and nuclear sclerosis), myopia and hyperopia in 834 sibling pairs within 486 extended pedigrees were performed. Suggestive evidence of linkage was found for hyperopia on chromosome 3, region q26 (empiric P = 5.34 × 10(-4)), a region that had shown significant genome-wide evidence of linkage to refraction and some evidence of linkage to hyperopia. In addition, the analysis replicated previously reported genome-wide significant linkages to 22q11 of adjusted refraction and myopia (empiric P = 4.43 × 10(-3) and 1.48 × 10(-3), respectively) and to 7p15 of refraction (empiric P = 9.43 × 10(-4)). Evidence was also found of linkage to refraction on 7q36 (empiric P = 2.32 × 10(-3)), a region previously linked to high myopia. The findings provide further evidence that genes controlling refractive errors are located on 3q26, 7p15, 7p36, and 22q11.

  2. Communication technologies for demand side management

    Energy Technology Data Exchange (ETDEWEB)

    Uuspaeae, P. [VTT Energy, Espoo (Finland)

    1998-08-01

    The scope of this research is data communications for electric utilities, specifically for the purposes of Demand Side Management (DSM). Demand Side Management has the objective to change the customer`s end use of energy in a manner that benefits both the customer and the utility. For example, peak demand may be reduced, and the peak demand may be relocated to off peak periods. Thus additional investments in generation and network may be avoided. A number of Demand Side Management functions can be implemented if a communication system is available between the Electric Utility and the Customer. The total communication capacity that is needed, will depend on several factors, such as the functions that are chosen for DSM, and on the number and type of customers. Some functions may be handled with one-way communications, while some other functions need to have two-way communication

  3. Estimation of School Bus Demand in China and Analysis of its Influencing Factors%全国校车需求量的估算及影响因素分析

    Institute of Scientific and Technical Information of China (English)

    王磊

    2014-01-01

    In recent years, school bus increasingly gets attention from the public and the government. The development of school bus relates to schools, students' parents, education authority, transportation companies and school bus producers, etc. The quantity demand is a key issue that determines the development of school bus. This paper estimates the potential quantity demand of school bus from the perspective of population development and school-age population gross after reviews the former estimation method. Besides, it analyzes the factors which influence the demand of school bus based on field work and interviews in several counties and cities.%近年来,校车问题逐渐引起党和政府以及全社会的重视。校车事业涉及到学校、学生家长、教育主管部门、交通运营公司和校车生产厂家等各方。校车需求量成为校车事业或校车产业发展中的一个关键问题。本文在回顾已有校车需求量估算方法的基础上,从人口发展的视角,从学龄人口总量角度估算了校车潜在需求量,并基于实地调查分析了影响校车需求量的人口、地理、经济和政治等因素。

  4. Regional Energy Demand Influence Factors Based on the Theory of Cointegration Analysis%基于协整理论的区域能源需求影响因素探析

    Institute of Scientific and Technical Information of China (English)

    关华; 赵黎明

    2013-01-01

    当前,由于环境的破坏以及常规能源储量的不断下降,能源需求结构急需调整。GDP、人口总量及产业结构等因素均会对能源需求量产生影响。为减少经济发展对能源需求不断增加的趋势,在制定能源发展战略时应充分考虑经济发展与节能二者的关系,控制好能源消费总量的增长,实现能源构成多元化,确保总体能源供应安全,提高能源效率,保护环境。同时,大力发展新能源产业,实现以最少的能源消耗支持经济持续发展的目标。%At present, due to the destruction of the environment and the falling of conventional energy reserves in urgent need of energy demand structure adjustment. Factors such as GDP, population, and industrial structure will impact on energy demand. To reduce the increasing demand for energy in the economic development trend, when making energy development strategy should give full consideration to the economic development and energy saving two relations, control the growth of the total energy consumption, realize the energy diversification, ensure that the overall energy supply security, energy efficiency, protect the environment. At the same time, vigorously develop new energy industry, implementation with minimal energy consumption to support the goal of sustainable economic development.

  5. Empirical Analysis of the Employment Demand Priority of New Generation Migrant Workers and Its Influencing Factors%新生代农民工择业需求优先序及其差异

    Institute of Scientific and Technical Information of China (English)

    彭安明; 朱红根; 康兰媛

    2014-01-01

    基于549份新生代农民工数据,运用聚类分析法对新生代农民工择业需求优先序进行考察,分析新生代农民工择业需求的影响因素,研究结果表明:第一,新生代农民工择业最关注工资收入情况,其次对个人发展、医疗保险、工作环境和权益保护的需求也较大;第二,新生代农民工择业需求影响因素的分析表明,不同个体特征的新生代农民工的择业需求存在差异,不同区域、不同企业新生代农民工的择业需求也存在差异。%Based on 549 copies of survey data made on the new generation of migrant workers,this paper firstly analyzes the employment demand priority of the new generation migrant workers by using cluster analysis and then analyses its influencing factors.Results show that new generation migrant workers pay most attention on wage income,and it is followed by personal development,medical insurance,working environment and rights protection.The analyzing results show that different characteristics of individual new generation migrant worker may have different employment demand.Migrant workers from different regions and different enterprises also have different demand on distinct working conditions.

  6. Travel Demand Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Southworth, Frank [ORNL; Garrow, Dr. Laurie [Georgia Institute of Technology

    2011-01-01

    This chapter describes the principal types of both passenger and freight demand models in use today, providing a brief history of model development supported by references to a number of popular texts on the subject, and directing the reader to papers covering some of the more recent technical developments in the area. Over the past half century a variety of methods have been used to estimate and forecast travel demands, drawing concepts from economic/utility maximization theory, transportation system optimization and spatial interaction theory, using and often combining solution techniques as varied as Box-Jenkins methods, non-linear multivariate regression, non-linear mathematical programming, and agent-based microsimulation.

  7. Education on Demand

    DEFF Research Database (Denmark)

    Boysen, Lis; Hende, Merete

    2015-01-01

    Dette notat beskriver nogle af resultaterne fra programmet "Education on Demand' i projektet Det erhvervsrettede Uddannelseslaboratorium. Programmet har haft fokus på udfordringer og forandringsbehov i uddannelsesinstitutioner og -systemet. Herunder har det beskæftiget sig særligt med de to temat......Dette notat beskriver nogle af resultaterne fra programmet "Education on Demand' i projektet Det erhvervsrettede Uddannelseslaboratorium. Programmet har haft fokus på udfordringer og forandringsbehov i uddannelsesinstitutioner og -systemet. Herunder har det beskæftiget sig særligt med de...

  8. Demand Modelling in Telecommunications

    Directory of Open Access Journals (Sweden)

    M. Chvalina

    2009-01-01

    Full Text Available This article analyses the existing possibilities for using Standard Statistical Methods and Artificial Intelligence Methods for a short-term forecast and simulation of demand in the field of telecommunications. The most widespread methods are based on Time Series Analysis. Nowadays, approaches based on Artificial Intelligence Methods, including Neural Networks, are booming. Separate approaches will be used in the study of Demand Modelling in Telecommunications, and the results of these models will be compared with actual guaranteed values. Then we will examine the quality of Neural Network models. 

  9. Comparing linkage designs based on land facets to linkage designs based on focal species.

    Science.gov (United States)

    Brost, Brian M; Beier, Paul

    2012-01-01

    Least-cost modeling for focal species is the most widely used method for designing conservation corridors and linkages. However, these designs depend on today's land covers, which will be altered by climate change. We recently proposed an alternative approach based on land facets (recurring landscape units of relatively uniform topography and soils). The rationale is that corridors with high continuity of individual land facets will facilitate movement of species associated with each facet today and in the future. Conservation practitioners might like to know whether a linkage design based on land facets is likely to provide continuity of modeled breeding habitat for species needing connectivity today, and whether a linkage for focal species provides continuity and interspersion of land facets. To address these questions, we compared linkages designed for focal species and land facets in three landscapes in Arizona, USA. We used two variables to measure linkage utility, namely distances between patches of modeled breeding habitat for 5-16 focal species in each linkage, and resistance profiles for focal species and land facets between patches connected by the linkage. Compared to focal species designs, linkage designs based on land facets provided as much or more modeled habitat connectivity for 25 of 28 species-landscape combinations, failing only for the three species with the most narrowly distributed habitat. Compared to land facets designs, focal species linkages provided lower connectivity for about half the land facets in two landscapes. In areas where a focal species approach to linkage design is not possible, our results suggest that conservation practitioners may be able to implement a land facets approach with some confidence that the linkage design would serve most potential focal species. In areas where focal species designs are possible, we recommend using the land facet approach to complement, rather than replace, focal species approaches.

  10. Energy demand and population change.

    Science.gov (United States)

    Allen, E L; Edmonds, J A

    1981-09-01

    During the post World War 2 years energy consumption has grown 136% while population grew about 51%; per capita consumption of energy expanded, therefore, about 60%. For a given population size, demographic changes mean an increase in energy needs; for instance the larger the group of retirement age people, the smaller their energy needs than are those for a younger group. Estimates indicate that by the year 2000 the energy impact will be toward higher per capita consumption with 60% of the population in the 19-61 age group of workers. Rising female labor force participation will increase the working group even more; it has also been found that income and energy grow at a proportional rate. The authors predict that gasoline consumption within the US will continue to rise with availability considering the larger number of female drivers and higher per capita incomes. The flow of illegal aliens (750,000/year) will have a major impact on income and will use greater amounts of energy than can be expected. A demographic change which will lower energy demands will be the slowdown of the rate of household formation caused by the falling number of young adults. The response of energy demand to price changes is small and slow but incomes play a larger role as does the number of personal automobiles and social changes affecting household formation. Households, commercial space, transportation, and industry are part of every demand analysis and population projections play a major role in determining these factors.

  11. Drivers of U.S. mineral demand

    Science.gov (United States)

    Sznopek, John L.

    2006-01-01

    Introduction: The word 'demand' has different meanings for different people. To some, it means their 'wants and needs,' to others it is what they consume. Yet, when considering economics, demand refers to the specific amounts of goods or services that individuals will purchase at various prices. Demand is measured over a given time period. It is determined by a number of factors including income, tastes, and the price of complementary and substitute goods. In this paper, the term consumption is used fairly synonymously with the term demand. Most mineral commodities, like iron ore, copper, zinc, and gravel, are intermediate goods, which means that they are used in the production of other goods, called final goods. Demand for intermediate goods is called derived demand because such demand is derived from the demand for final goods. When demand increases for a commodity, generally the price rises. With everything else held constant, this increases the profits for those who provide this commodity. Normally, this would increase profits of existing producers and attract new producers to the market. When demand for a commodity decreases, generally the price falls. Normally, this would cause profits to fall and, as a consequence, the least efficient firms may be forced from the industry. Demand changes for specific materials as final goods or production techniques are reengineered while maintaining or improving product performance, for example, the use of aluminum in the place of copper in long distance electrical transmission lines or plastic replacing steel in automobile bumpers. Substitution contributes to efficient material usage by utilizing cheaper or technically superior materials. In this way, it may also alleviate materials scarcity. If a material becomes relatively scarce (and thus more expensive), a more abundant (and less expensive) material generally replaces it (Wagner and others, 2003, p. 91).

  12. Oil supply and demand

    Energy Technology Data Exchange (ETDEWEB)

    Rech, O

    2004-07-01

    World oil demand, driven by economic development in China, posted the highest growth rate in 20 years. In a context of geopolitical uncertainty, prices are soaring, encouraged by low inventory and the low availability of residual production capacity. Will 2004 bring a change in the oil market paradigm? (author)

  13. The demand for euros

    NARCIS (Netherlands)

    Arnold, I.J.M.; Roelands, S.

    2010-01-01

    This paper investigates the demand for euros using panel data for 10 euro area countries covering the period from 1999 to 2008. Monetary aggregates are constructed to ensure that money is a national concept by excluding deposits owned by non-residents and including external deposits owned by

  14. Surveys and forecasting industrial property demand

    OpenAIRE

    2011-01-01

    The aim of this paper is to increase the knowledge about industrial land and floor space forecasting. From the rare research on this subject it is known that the knowledge about factors that influence demand and techniques that model demand is not available in abundance. However, different kinds of models are used extensively in practice. This paper focuses the difference between of stated and revealed preferences. In planning practices stated preferences are often used to forecast land and f...

  15. An Empirical Study on the factors of insurance demand in China-based on quantile regression of time sequence%中国保险需求影响因素的实证研究--基于时间序列的分位数回归

    Institute of Scientific and Technical Information of China (English)

    尚君; 陈艺源; 马捷; 任燕燕

    2013-01-01

    This article uses the related time series data from 1985 to 2011 to make the empirical analyses on the different influence degree of per capita GDP, per capita education expenditure and the disposable income of residents on life insurance demand and property insurance demand under different demand level using the co-integration analysis and quantile regression method. The results show that:all the three factors have significant positive effect on the life insurance demand and property insurance demand, But on the whole, the influence degree of various factors on the life insurance demand are greater than the property insurance demand.And, under different levels of insurance demand, the influence degree of all influencing factors presents difference for both life insurance demand and property insurance demand.%本文采用1985-2011年的相关时间序列数据,运用协整分析和分位数回归方法,将保险需求细分为人身保险需求和财产保险需求,分别分析了在不同需求水平下人均GDP、人均教育支出和居民可支配收入对保险需求的影响程度,结果表明:三个影响因素对人身保险需求和财产保险需求均存在显著的正向作用,但整体而言,各个因素对人身保险需求的影响程度均大于对财产保险需求的影响程度;在不同的保险需求水平下,各个影响因素的影响程度存在差异。

  16. Finding what works: Predicting health or social service linkage in drug using, African American, female sex workers in Miami, FL.

    Science.gov (United States)

    Levi-Minzi, Maria A; Surratt, Hilary L; O'Grady, Catherine L; Kurtz, Steven P

    2016-07-01

    Female sex workers (FSWs) encounter numerous challenges in accessing health and social services. In this study of drug using, African American FSWs, the authors examine specific factors associated with health or social service linkage among participants in a randomized intervention trial. Respondent linkage was significantly associated with individual factors (living alone, severe internal mental distress, and traumatic victimization) and project-related variables (attending five case management sessions and client engagement rating). In the multivariate model, higher client engagement and session attendance remained significant. The researchers conclude by discussing the importance of intervention attendance and engagement as key contributors to health and social service linkage among FSWs.

  17. Inter-organizational linkages and resource dependence

    Directory of Open Access Journals (Sweden)

    Rod B. McNaughton

    2014-12-01

    Full Text Available Few studies have examined the relationship between inter-industry, inter-corporate ownership (ICO patterns and inter-industry resource exchange patterns. Using data from Statistics Canada, this paper reveals a positive association between the degree of ICO linkages and the degree of input–output dependence among Canadian industry groups. This provides empirical support for the primary assertion of resource dependence theory: that corporations employ ICO linkages to manage their input–output dependence resulting from recurrent resource exchanges. This research differs from extant tests of resource dependence in that it uses data for the population of firms (over a size threshold in Canada and includes all forms of interdependence between enterprises. The findings suggest scenarios in which corporations can adopt ICO linkages to manage resource dependence and reduce transaction costs.

  18. Intragroup Emotions: Physiological Linkage and Social Presence

    Science.gov (United States)

    Järvelä, Simo; Kätsyri, Jari; Ravaja, Niklas; Chanel, Guillaume; Henttonen, Pentti

    2016-01-01

    We investigated how technologically mediating two different components of emotion—communicative expression and physiological state—to group members affects physiological linkage and self-reported feelings in a small group during video viewing. In different conditions the availability of second screen text chat (communicative expression) and visualization of group level physiological heart rates and their dyadic linkage (physiology) was varied. Within this four person group two participants formed a physically co-located dyad and the other two were individually situated in two separate rooms. We found that text chat always increased heart rate synchrony but HR visualization only with non-co-located dyads. We also found that physiological linkage was strongly connected to self-reported social presence. The results encourage further exploration of the possibilities of sharing group member's physiological components of emotion by technological means to enhance mediated communication and strengthen social presence. PMID:26903913

  19. Intragroup emotions: physiological linkage and social presence

    Directory of Open Access Journals (Sweden)

    Simo eJärvelä

    2016-02-01

    Full Text Available We investigated how technologically mediating two different components of emotion – communicative expression and physiological state – to group members affects physiological linkage and self-reported feelings in a small group during video viewing. In different conditions the availability of second screen text chat (communicative expression and visualization of group level physiological heart rates and their dyadic linkage (physiology was varied. Within this four person group two participants formed a physically co-located dyad and the other two were individually situated in two separate rooms. We found that text chat always increased heart rate synchrony but HR visualization only with non-co-located dyads. We also found that physiological linkage was strongly connected to self-reported social presence. The results encourage further exploration of the possibilities of sharing group member’s physiological components of emotion by technological means to enhance mediated communication and strengthen social presence.

  20. Demand surge following earthquakes

    Science.gov (United States)

    Olsen, Anna H.

    2012-01-01

    Demand surge is understood to be a socio-economic phenomenon where repair costs for the same damage are higher after large- versus small-scale natural disasters. It has reportedly increased monetary losses by 20 to 50%. In previous work, a model for the increased costs of reconstruction labor and materials was developed for hurricanes in the Southeast United States. The model showed that labor cost increases, rather than the material component, drove the total repair cost increases, and this finding could be extended to earthquakes. A study of past large-scale disasters suggested that there may be additional explanations for demand surge. Two such explanations specific to earthquakes are the exclusion of insurance coverage for earthquake damage and possible concurrent causation of damage from an earthquake followed by fire or tsunami. Additional research into these aspects might provide a better explanation for increased monetary losses after large- vs. small-scale earthquakes.

  1. Market Expects Demand Increase

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In the recent releasing Textile Industry Invigorating Plan,"givingattention to both domestlc and overseas markets"is put into a keyposition.Under a series policies,such as increasing the tax rebaterate for textile and garment exports,and granting loan for SME,thefurther development of this industry is expectative.Otherwise,weshould know that it costs time for demand driving.This need ourpatients.The only questionis how much time we have to wait.

  2. Migration and Tourism Demand

    Directory of Open Access Journals (Sweden)

    Nuno Carlos LEITÃO

    2012-02-01

    Full Text Available This study considers the relationship between immigration and Portuguese tourism demand for the period 1995-2008, using a dynamic panel data approach. The findings indicate that Portuguese tourism increased significantly during the period in accordance with the values expected for a developed country. The regression results show that income, shock of immigration, population, and geographical distance between Portugal and countries of origin are the main determinants of Portuguese tourism.

  3. Bronx Teens Connection's Clinic Linkage Model: Connecting Youth to Quality Sexual and Reproductive Health Care.

    Science.gov (United States)

    O'Uhuru, Deborah J; Santiago, Vivian; Murray, Lauren E; Travers, Madeline; Bedell, Jane F

    2017-03-01

    Teen pregnancy and birth rates in the Bronx have been higher than in New York City, representing a longstanding health disparity. The New York City Department of Health and Mental Hygiene implemented a community-wide, multicomponent intervention to reduce unintended teen pregnancy, the Bronx Teens Connection. The Bronx Teens Connection Clinic Linkage Model sought to increase teens' access to and use of sexual and reproductive health care by increasing community partner capacity to link neighborhood clinics to youth-serving organizations, including schools. The Bronx Teens Connection Clinic Linkage Model used needs assessments, delineated the criteria for linkages, clarified roles and responsibilities of partners and staff, established trainings to support the staff engaged in linkage activities, and developed and used process evaluation methods. Early results demonstrated the strength and feasibility of the model over a 4-year period, with 31 linkages developed and maintained, over 11,300 contacts between clinic health educators and teens completed, and increasing adherence to the Centers for Disease Control and Prevention-defined clinical best practices for adolescent reproductive health. For those eight clinics that were able to provide data, there was a 25% increase in the number of teen clients seen over 4 years. There are many factors that relate to an increase in clinic utilization; some of this increase may have been a result of the linkages between schools and clinics. The Bronx Teens Connection Clinic Linkage Model is an explicit framework for clinical and youth-serving organizations seeking to establish formal linkage relationships that may be useful for other municipalities or organizations. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  4. Some methods for blindfolded record linkage

    Directory of Open Access Journals (Sweden)

    Christen Peter

    2004-06-01

    Full Text Available Abstract Background The linkage of records which refer to the same entity in separate data collections is a common requirement in public health and biomedical research. Traditionally, record linkage techniques have required that all the identifying data in which links are sought be revealed to at least one party, often a third party. This necessarily invades personal privacy and requires complete trust in the intentions of that party and their ability to maintain security and confidentiality. Dusserre, Quantin, Bouzelat and colleagues have demonstrated that it is possible to use secure one-way hash transformations to carry out follow-up epidemiological studies without any party having to reveal identifying information about any of the subjects – a technique which we refer to as "blindfolded record linkage". A limitation of their method is that only exact comparisons of values are possible, although phonetic encoding of names and other strings can be used to allow for some types of typographical variation and data errors. Methods A method is described which permits the calculation of a general similarity measure, the n-gram score, without having to reveal the data being compared, albeit at some cost in computation and data communication. This method can be combined with public key cryptography and automatic estimation of linkage model parameters to create an overall system for blindfolded record linkage. Results The system described offers good protection against misdeeds or security failures by any one party, but remains vulnerable to collusion between or simultaneous compromise of two or more parties involved in the linkage operation. In order to reduce the likelihood of this, the use of last-minute allocation of tasks to substitutable servers is proposed. Proof-of-concept computer programmes written in the Python programming language are provided to illustrate the similarity comparison protocol. Conclusion Although the protocols described in

  5. Genetic linkage heterogeneity in the fragile X syndrome.

    Science.gov (United States)

    Brown, W T; Gross, A C; Chan, C B; Jenkins, E C

    1985-01-01

    Genetic linkage between a factor IX DNA restriction fragment length polymorphism (RFLP) and the fragile X chromosome marker was analyzed in eight fragile X pedigrees and compared to eight previously reported pedigrees. A large pedigree with apparently full penetrance in all male members showed a high frequency of recombination. A lod score of -7.39 at theta = 0 and a maximum score of 0.26 at theta = 0.32 were calculated. A second large pedigree with a nonpenetrant male showed tight linkage with a maximum lod score of 3.13 at theta = 0, a result similar to one large pedigree with a nonpenetrant male previously reported. The differences in lod scores seen in these large pedigrees suggested there was genetic heterogeneity in linkage between families which appeared to relate to the presence of nonpenetrant males. The combined lod score for the three pedigrees with nonpenetrant males was 6.84 at theta = 0. For the 13 other pedigrees without nonpenetrant males the combined lod score was -21.81 at theta = 0, with a peak of 0.98 at theta = 0.28. When lod scores from all 16 families were combined, the value was -15.14 at theta = 0 and the overall maximum was 5.13 at theta = 0.17. To determine whether genetic heterogeneity was present, three statistical tests for heterogeneity were employed. First, a "predivided-sample" test was used. The 16 pedigrees were divided into two classes, NP and P, based upon whether or not any nonpenetrant males were detected in the pedigree. This test gave evidence for significant genetic heterogeneity whether the three large pedigrees with seven or more informative males (P less than 0.005), the eight pedigrees with three informative males (P less than 0.001), or all 16 pedigrees (P less than 0.001) were included in the analysis. Second, Morton's large sample test was employed. Significant heterogeneity was present when the analysis was restricted to the three large pedigrees (P less than 0.025), or to the eight pedigrees with informative males

  6. Cognitive task demands, self-control demands and the mental well-being of office workers.

    Science.gov (United States)

    Bridger, Robert S; Brasher, Kate

    2011-09-01

    The cognitive task demands of office workers and the self-control demands of their work roles were measured in a sample of 196 employees in two different office layouts using a self-report questionnaire, which was circulated electronically. Multiple linear regression analysis revealed that both factors were associated with mental well-being, but not with physical well-being, while controlling for exposure to psychosocial stressors. The interaction between cognitive task demands and self-control demands had the strongest association with mental well-being, suggesting that the deleterious effect of one was greater when the other was present. An exploratory analysis revealed that the association was stronger for employees working in a large open-plan office than for those working in smaller offices with more privacy. Frustration of work goals was the cognitive task demand having the strongest negative impact on mental well-being. Methodological limitations and scale psychometrics (particularly the use of the NASA Task Load Index) are discussed. STATEMENT OF RELEVANCE: Modern office work has high mental demands and low physical demands and there is a need to design offices to prevent adverse psychological reactions. It is shown that cognitive task demands interact with self-control demands to degrade mental well-being. The association was stronger in an open-plan office.

  7. Analysis on the Influence Factors of Supply and Demand of Edible Wildlife%食用型野生动物供需的影响因素分析

    Institute of Scientific and Technical Information of China (English)

    时小琳; 戴永务; 石德金

    2012-01-01

      以经济学中的供求理论为基础,首先从价格、收入水平和消费者偏好等因素对食用型野生动物的市场需求特征进行了分析,研究表明食用型野生动物产品的价格及人们的收入水平是影响大众对其消费欲望的最主要因素;其次,从商品价格、生产者预期、养殖技术、养殖成本、政府政策和气候条件等因素分析了食用型野生动物的市场供给特征,研究表明养殖技术、养殖成本和政府政策是制约食用型野生动物产品供给最为重要的三大影响因素;从供需两个角度看,气候条件的变化、较好的生产者预期和对野生动物产品的偏好等因素一定程度上也影响了食用型野生动物养殖业的顺利发展;然后,运用 AD-AS 模型对食用型野生动物养殖业的市场发展潜力进行分析;最后提出相应的政策建议%  On the basis of the theory of supply and demand in economics,this paper firstly analyzes the demand characteristics of edible wildlife from the factors which include price,income level and consumer preferences.It shows that the edible wildlife products' prices and the people's income level are the main factors that influencing public's desires to consume.Secondly,the paper analyzes the supply characteristics of edible wildlife from the factors which include commodity prices,producer expectations,farming technologies,farming cost,government policies and climate conditions.It shows that farming technologies, farming cost and government policies are the most important restrictive factors to the supply of the edible wildlife products.From the two perspectives of supply and demand,to some extent,the changing of the climate conditions,the good producer expectations and the consumer preferences to the wildlife products also affect the smooth development of edible wildlife farming.Then the paper analyzes the market development potential of edible wildlife farming by

  8. 营养专业人才社会需求现况及影响因素分析%Study on social demand status and influencing factors of nutrition profession

    Institute of Scientific and Technical Information of China (English)

    邵继红; 苗柳; 谢蒙蒙; 黄水平; 徐莉春; 王锋; 周丽; 任香梅

    2014-01-01

    Objective To investigate the social demand status and influencing factors of nutrition profession in order to provide advices for nutrition personnel training and policy-setting.Methods A stratified cluster sampling was conducted in southern,middle and north of Jiangsu province with questionnaire to understand the basic infomation of interviewees,job category,basic infomation of the unit and the demand for nutrition talents.The data were input by Epidata 3.1 and were analyzed by SPSS 17.0.The basic infomation of intmviewees and the demand of units were analyzed by chi-square test while influencing factor of nutrition talent demand were analyzed by single factor and muhiple factors logistic regression analysis.Results Survey resuhs showed that there were differences in professional level among different areas(P=0.011).Nutrition talents mainly worked in catering services (P=0.019).In the next three years,45.9% of the smvey units will have nutrition professional demand and nutrition talents will mainly work in nursing homes,health care products marketing,community,schools and service institutions(P=0.009).67.8% of the smvey units will require bachelor degree(P=0.005) and 89.9% of the smvey units will take nutrition profession as priority(P=0.000).Gender,postgraduate degree,nutrition profession and actual operation ability are the main influencing factors for choosing and employing(P<0.05).Conclusions At present,nutrition talents are mainly bachelor's degree.Nutrition personnel training should pay attention to the compositionality and applicability and need classification development to meet the social sustainability needs.%目的 了解社会对营养专业人才的社会需求及影响因素,为人才培养和政策制定提供依据.方法 采用分层抽样方法,对苏南、苏北和苏中地区各类单位相关人员共420人进行问卷调查,了解被调查者基本情况、工作类别,其单位基本情况、对营养人才的需求

  9. Tobacco-free economy: A SAM-based multiplier model to quantify the impact of changes in tobacco demand in Bangladesh.

    Science.gov (United States)

    Husain, Muhammad Jami; Khondker, Bazlul Haque

    2016-01-01

    In Bangladesh, where tobacco use is pervasive, reducing tobacco use is economically beneficial. This paper uses the latest Bangladesh social accounting matrix (SAM) multiplier model to quantify the economy-wide impact of demand-driven changes in tobacco cultivation, bidi industries, and cigarette industries. First, we compute various income multiplier values (i.e. backward linkages) for all production activities in the economy to quantify the impact of changes in demand for the corresponding products on gross output for 86 activities, demand for 86 commodities, returns to four factors of production, and income for eight household groups. Next, we rank tobacco production activities by income multiplier values relative to other sectors. Finally, we present three hypothetical 'tobacco-free economy' scenarios by diverting demand from tobacco products into other sectors of the economy and quantifying the economy-wide impact. The simulation exercises with three different tobacco-free scenarios show that, compared to the baseline values, total sectoral output increases by 0.92%, 1.3%, and 0.75%. The corresponding increases in the total factor returns (i.e. GDP) are 1.57%, 1.75%, and 1.75%. Similarly, total household income increases by 1.40%, 1.58%, and 1.55%.

  10. Meeting increased demand.

    Science.gov (United States)

    Blair, Andrew

    2004-07-01

    New Zealand is a little country with a little economy but with a population that's rapidly aging. New Zealand's population is only 4.3 million people. It's GDP is only $US58.6 billion (2002). New Zealand's expenditure on health as a percentage of GDP is not out of line with that of other countries. As a nation we have been increasing expenditure on health over recent years. In 1990 we spent 7% of GDP on health. In 1995 that increased to 7.65% and is now 8.3%. However, in per capita terms our expenditure on health does not compare so well with like countries. The size of New Zealand's economy is restricting what our country spends on health. Health is already the second highest demand on the New Zealand tax dollar. The tolerance of New Zealanders would be challenged if a Government attempted to increase taxes further to meet the growing demands for expenditure on health, but at the same time the population's expectations are increasing. This is the challenging situation we face today. What lies ahead? Like all industrialized countries New Zealand is facing an aging population. The population below age 40 is decreasing, but it is increasing significantly over that age. 16% of the population is currently aged over 60. By 2051 this proportion will almost double to just over 31%. Coupled with the aging population is increased awareness and expectations, as access to options for treatment and technology becomes readily accessible to the population through such media as the internet. The extent of the impact of the aging population can be clearly represented by focusing on one specialty such as orthopaedics. The New Zealand Orthopaecic Association undertook a study in July 2003 which concluded (among other things) that as a result of the projected aging of the population, over the next 50 years: Musculo-skeletal operations will increase by over 30%. The number of hip replacements will nearly double. The incidence of osteoporosis will increase by a massive 201%. The number

  11. Producer Services, Manufacturing Linkages, and Trade

    NARCIS (Netherlands)

    J.F. François (Joseph); J. Kepler; J. Woerz

    2007-01-01

    textabstractWorking with a mix of panel data on goods and services trade for the OECD for 1994-2004, combined with social accounts data (i.e. data on intermediate linkages) for 78 countries benchmarked to the panel midpoint, we examine the role of services as inputs in manufacturing, with a particul

  12. Asset Market Linkages in Crisis Periods

    NARCIS (Netherlands)

    P. Hartmann; S. Straetmans; C.G. de Vries (Casper)

    2001-01-01

    textabstractWe characterize asset return linkages during periods of stress by an extremal dependence measure. Contrary to correlation analysis, this non-parametric measure is not predisposed towards the normal distribution and can account for non-linear relationships. Our estimates for the G-5 count

  13. Asset Market Linkages in Crisis Periods

    NARCIS (Netherlands)

    P. Hartmann; S. Straetmans; C.G. de Vries (Casper)

    2001-01-01

    textabstractWe characterize asset return linkages during periods of stress by an extremal dependence measure. Contrary to correlation analysis, this non-parametric measure is not predisposed towards the normal distribution and can account for non-linear relationships. Our estimates for the G-5

  14. The Barley Chromosome 5 Linkage Map

    DEFF Research Database (Denmark)

    Jensen, J.; Jørgensen, Jørgen Helms

    1975-01-01

    : wst5 (white streaks), necl (necrotic leaf spots), Ml-nn (powdery mildew resistance), and Pa4 (leaf rust resistance). Further, the two sections of the map are united, and the precision of the map is improved. A system for designating the positions of the loci on the linkage map is proposed. A 0...

  15. Linkage analysis of chromosome 14 and essential hypertension in Chinese population

    Institute of Scientific and Technical Information of China (English)

    ZHAO Wei-yan; HUANG Jian-feng; GE Dong-liang; SU Shao-yong; LI Biao; GU Dong-feng

    2005-01-01

    Background Hypertension is a complex biological trait that influenced by multiple factors. The encouraging results for hypertension research showed that the linkage analysis can be used to replicate other studies and discover new genetic risk factors. Previous studies linked human chromosome 14 to essential hypertension or blood pressure traits. With a Chinese population, we tried to replicate these findings. Methods A linkage scan was performed on chromosome 14 with 14-microsatellite markers with a density of about 10 centi Morgen (cM) in 147 Chinese hypertensive nuclear families. Multipoint non-parametric linkage analysis and exclusion mapping were performed with the GENEHUNTER software, whereas quantitative analysis was performed with the variance component method integrated in the SOLAR package. Results In the qualitative analysis, the highest non-parametric linkage score is 1.0 (P=0.14) at D14S261 in the single point analysis, and no loci achieved non-parametric linkage score more than 1.0 in the multipoint analysis. Maximum-likelihood mapping showed no significant results, either. Subsequently the traditional exclusion criteria of the log-of-the-odds score-2 were adopted, and the chromosome 14 with λs≥2.4 was excluded. In the quantitative analysis of blood pressure with the SOLAR software, two-point analysis and multipoint analysis suggested no evidence for linkage occurred on chromosome 14 for systolic and diastolic blood pressure. Conclusion There was no substantial evidence to support the linkage of chromosome 14 and essential hypertension or blood pressure trait in Chinese hypertensive subjects in this study.

  16. QTL linkage analysis of connected populations using ancestral marker and pedigree information.

    Science.gov (United States)

    Bink, Marco C A M; Totir, L Radu; ter Braak, Cajo J F; Winkler, Christopher R; Boer, Martin P; Smith, Oscar S

    2012-04-01

    The common assumption in quantitative trait locus (QTL) linkage mapping studies that parents of multiple connected populations are unrelated is unrealistic for many plant breeding programs. We remove this assumption and propose a Bayesian approach that clusters the alleles of the parents of the current mapping populations from locus-specific identity by descent (IBD) matrices that capture ancestral marker and pedigree information. Moreover, we demonstrate how the parental IBD data can be incorporated into a QTL linkage analysis framework by using two approaches: a Threshold IBD model (TIBD) and a Latent Ancestral Allele Model (LAAM). The TIBD and LAAM models are empirically tested via numerical simulation based on the structure of a commercial maize breeding program. The simulations included a pilot dataset with closely linked QTL on a single linkage group and 100 replicated datasets with five linkage groups harboring four unlinked QTL. The simulation results show that including parental IBD data (similarly for TIBD and LAAM) significantly improves the power and particularly accuracy of QTL mapping, e.g., position, effect size and individuals' genotype probability without significantly increasing computational demand.

  17. ANALYSIS ON AGRICULTRUAL INFORMATION DEMAND --Case of Jilin Province

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hui-min; JIANG Hui-ming

    2005-01-01

    With the rapid development of agricultural informalization in the world, the demand of agricultural information has been a focus in the international agriculture and information fields. Based on the investigation, this paper presented the four characteristics of the demand of agricultural information in China, including regionality, seasonality, great potential demand and variation in kind and level. The factors influencing the demand of agricultural information were analyzed by the Optimized Less Square (OLS) method. The result shows that, of all factors influcing agricultural information demand, the most important one is economy, the second is facility of information pass,and knowledge and education of user, credit of agricultural information service system and production situation follow. Taking Jilin Province as an example, this article also elaborated the agricultural information demand status, and deduced the regression model of agricultural information demand and verified it by the survey in rural Jilin.

  18. Autosomal dominant familial spastic paraplegia; Linkage analysis and evidence for linkage to chromosome 2p

    Energy Technology Data Exchange (ETDEWEB)

    Figlewicz, D.A. [Univ. of Rochester, NY (United States); Dube, M.P.; Rouleau, G.A. [McGill Univ., Montreal (Canada)] [and others

    1994-09-01

    Familial spastic paraplegia (FSP) is a degenerative disorder of the motor system characterized by progressive weakness and spasticity of the lower limbs. Little is known about the pathophysiology of this disorder. FSP can be inherited as an autosomal dominant (AD), autosomal recessive, or X-linked trait. We have undertaken linkage analysis for a group of 36 AD FSP families from which we have collected blood samples from 427 individuals, including 148 affected individuals. Typing of polymorphic markers has allowed us to exclude more than 50% of the genome. Recently, linkage for AD FSP to a locus on chromosome 14q was reported. Our AD FSP kindreds were tested for linkage to markers spanning the 20 cM region between D14S69 and D14S66; however, we were not able to establish linkage for any of our families to chromosome 14. Lod scores suggestive of linkage for some AD FSP kindreds have been obtained for markers on chromosome 2p. We have tested seven polymorphic markers spanning the region between D2S405 and D2S177. Our highest aggregate lod score, including all families tested, was obtained at the locus D2S352: 2.4 at 20 cM. Results from HOMOG analysis for linkage heterogeneity will be reported.

  19. Availability of Insurance Linkage Programs in U.S. Emergency Departments

    Directory of Open Access Journals (Sweden)

    Mia Kanak

    2014-07-01

    Full Text Available Introduction: As millions of uninsured citizens who use emergency department (ED services are now eligible for health insurance under the Affordable Care Act, the ED is ideally situated to facilitate linkage to insurance. Forty percent of U.S. EDs report having an insurance linkage program. This is the first national study to examine the characteristics of EDs that offer or do not offer these programs. Methods: This was a secondary analysis of data from the National Survey for Preventive Health Services in U.S. EDs conducted in 2008-09. We compared EDs with and without insurance programs across demographic and operational factors using univariate analysis. We then tested our hypotheses using multivariable logistic regression. We also further examined program capacity and priority among the sub-group of EDs with no insurance linkage program. Results: After adjustment, ED-insurance linkage programs were more likely to be located in the West (RR= 2.06, 95% CI = 1.33 – 2.72. The proportion of uninsured patients in an ED, teaching hospital status, and public ownership status were not associated with insurance linkage availability. EDs with linkage programs also offer more preventive services (RR = 1.87, 95% CI = 1.37–2.35 and have greater social worker availability (RR = 1.71, 95% CI = 1.12–2.33 than those who do not. Four of five EDs with a patient mix of ≥25% uninsured and no insurance linkage program reported that they could not offer a program with existing staff and funding. Conclusion: Availability of insurance linkage programs in the ED is not associated with the proportion of uninsured patients served by an ED. Policy or hospital-based interventions to increase insurance linkage should first target the 27% of EDs with high rates of uninsured patients that lack adequate program capacity. Further research on barriers to implementation and cost effectiveness may help to facilitate increased adoption of insurance linkage programs. [West J

  20. CONSUMER DEMAND FOR FOOD DIVERSITY

    OpenAIRE

    Lee, Jonq-Ying; Mark G. Brown

    1989-01-01

    In this paper, consumer demand for food diversity is measured by the entropy and Simpson indices for budget shares. Results show that consumer demand for food diversity is related to total food expenditures and household size and composition.

  1. Study of forecasting technique of power demand

    Energy Technology Data Exchange (ETDEWEB)

    Jung, T.Y. [Korea Energy Economics Institute, Euiwang (Korea, Republic of)

    1998-04-01

    Long-term forecast of power and energy demand become an important base of investment plan of the energy supply sector, and a study based on value data is indispensable since the expansion of energy supply requires a long construction period and a lot of investment capital. Total estimated power and energy demand of the whole economy is known to have considerable relationship with macroeconomics factors. This study reviews the Kalman filter technique and abnormal time series analysis technique which is useful in analyzing energy and macroeconomics data taking the form of pre-tallied time series data. Based on these, power demand and energy demand are estimated using real data and the most reliable technique, and long-term forecast of power and energy demand is tried up to year 2015 based on the forecasted values. It should be noted that power and energy demand of Korea shows the structurally-changing behavior based on the present while the forecast based on past data involves an assumption naturally that the trend continues from the past to the present. 15 refs., 8 figs., 15 tabs.

  2. Bioeconomic Analysis of Pesticide Demand

    OpenAIRE

    Moffitt, L. Joe; Farnsworth, Richard L.

    1981-01-01

    The ability of insects to develop resistance to specific pesticides affects pesticide demand. However, the affect of resistance on demand cannot be observed or measured. This analysis substitutes an expression for the unobserved resistance variable in a pesticide demand model and then illustrates the model's potential by estimating demand for DDT. To arrive at the expression characterizing the unobserved resistance variable a biological resistance model is constructed then incorporated into t...

  3. Rewarding yet demanding

    DEFF Research Database (Denmark)

    Bjørkedal, S T B; Torsting, A M B; Møller, T

    2016-01-01

    AIM: The purpose of this study, by exploring client perspectives, was to achieve a better understanding of how people with schizophrenia experience an occupational therapy intervention designed to enable them to carry out meaningful occupations in the early phases of recovery. METHOD: A qualitative......, as demanding. Participants valued engaging in real-life occupations while anchoring new strategies but also the occupational therapist's role in dealing with failure. Participants felt the intervention assisted in their recovery process and enabled them to engage in meaningful occupations. CONCLUSION......: The study provided unique insight into how participants experienced a client-centred partnership with an occupational therapist in the early phases of recovery. The intervention was feasible and supported the participants' recovery process....

  4. Physical demands in worklife.

    Science.gov (United States)

    Astrand, I

    1988-01-01

    Industrial occupations which are physically strenuous in the traditional sense of the word have decreased in number. They have partly been replaced by "light," repetitive, monotonous work tasks performed in a sitting position. The number of heavy work tasks within the service sector has increased. Specialization has been intensified. The individual's capacity for strenuous work is still of importance to successful work performance. Many studies show that an optional choice of work pace in physically demanding occupational work results in an adaptation of pace or intensity until the worker is utilizing 40-50% of her or his capacity. When the work rate is constrained, the relative strain of the individual varies inversely with the physical work capacity. The frequency of musculoskeletal disorders has concurrently increased with the implementation of industrial mechanization. New, wise, ergonomic moves are needed to stop this development.

  5. Participatory Demand-supply Systems

    NARCIS (Netherlands)

    Rezaee, S.A.; Oey, M.A.; Nevejan, C.I.M.; Brazier, F.M.

    2015-01-01

    Introducing the notion of Participatory Demand-Supply (PDS) systems as socio-technical systems, this paper focuses on a new approach to coordinating demand and supply in dynamic environments. A participatory approach to demand and supply provides a new frame of reference for system design, for which

  6. Participatory Demand-supply Systems

    NARCIS (Netherlands)

    Rezaee, S.A.; Oey, M.A.; Nevejan, C.I.M.; Brazier, F.M.

    2015-01-01

    Introducing the notion of Participatory Demand-Supply (PDS) systems as socio-technical systems, this paper focuses on a new approach to coordinating demand and supply in dynamic environments. A participatory approach to demand and supply provides a new frame of reference for system design, for which

  7. 武汉市城区老年健康服务需求的影响因素调查%The Influence Factors' Research of Urban Elderly Health Services Demand

    Institute of Scientific and Technical Information of China (English)

    陈阳; 金新政

    2016-01-01

    目的:探讨城市社区老年人的健康服务需求影响因素。方法采用问卷调查的方法对武汉市老年人进行问卷调查,并用统计分析方法分析调查数据。结果通过对数据进行统计学分析,影响城区老年人选择社区健康服务中心的因素主要有就诊单位的信誉、就诊单位的医疗设备配置以及自觉健康状况、慢性病的患病情况等因素。结论社区健康服务中心应该根据老年人的健康服务需求进一步加强健康服务建设,使服务更加系统化、规范化。%Objectives To explore the influential factors of urban community health services demand. Methods This research adopted the method of questionnaire analysis and literature analysis method, and statistical analysis methods to analyze research data. Results By using statistical analysis, we found that the reputation of the department, clinic medical equipment configuration, self-conscious health condition, and the prevalence of chronic diseases’P value is less than 0.05. These factors in influencing the choice of the elderly in community health service center are significant. Conclusion Community health service centers should strengthen the construction of health service and make services more systematically and standardized according to the elderly health service needs.

  8. Varieties of religion-family linkages.

    Science.gov (United States)

    Snarey, J R; Dollahite, D C

    2001-12-01

    The 4 articles in this special issue make important contributions to both family and religious studies as well as to their interface. This commentary begins by considering 4 unifying themes present across all of the articles, including meaningful religion-family linkages, the importance of gender differences in the faith-family interface, the significance of intergenerational relationships, and the need for better theory. The authors then discuss the unique major strength and secondary limitations of each study. Finally, the commentary focuses on two challenges inhibiting the contemporary study of religion and the family--a relative lack of racial and religious diversity in samples and the lack of a unifying theory of religion-family linkages--and suggests how to adjust the trajectory of future theory and research to address these issues.

  9. Genomewide linkage scan for myopia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 22q12.

    Science.gov (United States)

    Stambolian, Dwight; Ibay, Grace; Reider, Lauren; Dana, Debra; Moy, Chris; Schlifka, Melissa; Holmes, Taura; Ciner, Elise; Bailey-Wilson, Joan E

    2004-09-01

    Mild/moderate (common) myopia is a very common disorder, with both genetic and environmental influences. The environmental factors are related to near work and can be measured. There are no known genetic loci for common myopia. Our goal is to find evidence for a myopia susceptibility gene causing common myopia. Cycloplegic and manifest refraction were performed on 44 large American families of Ashkenazi Jewish descent, each with at least two affected siblings. Individuals with at least -1.00 diopter or lower in each meridian of both eyes were classified as myopic. Microsatellite genotyping with 387 markers was performed by the Center for Inherited Disease Research. Linkage analyses were conducted with parametric and nonparametric methods by use of 12 different penetrance models. The family-based association test was used for an association scan. A maximum multipoint parametric heterogeneity LOD (HLOD) score of 3.54 was observed at marker D22S685, and nonparametric linkage analyses gave consistent results, with a P value of.0002 at this marker. The parametric multipoint HLOD scores exceeded 3.0 for a 4-cM interval, and significant evidence of genetic heterogeneity was observed. This genomewide scan is the first step toward identifying a gene on chromosome 22 with an influence on common myopia. At present, we are following up our linkage results on chromosome 22 with a dense map of >1,500 single-nucleotide-polymorphism markers for fine mapping and association analyses. Identification of a susceptibility locus in this region may eventually lead to a better understanding of gene-environment interactions in the causation of this complex trait.

  10. Genome-wide linkage screen for testicular germ cell tumour susceptibility loci

    NARCIS (Netherlands)

    Crockford, GP; Linger, R; Hockley, S; Dudakia, D; Johnson, L; Huddart, R; Tucker, K; Friedlander, M; Phillips, KA; Hogg, D; Jewett, MAS; Lohynska, R; Daugaard, G; Richard, S; Chompret, A; Bonaiti-Pellie, C; Heidenreich, A; Albers, P; Olah, E; Geczi, L; Bodrogi, [No Value; Ormiston, WJ; Daly, PA; Guilford, P; Fossa, SD; Heimdal, K; Tjulandin, SA; Liubchenko, L; Stoll, H; Weber, W; Forman, D; Oliver, T; Einhorn, L; McMaster, M; Kramer, J; Greene, MH; Weber, BL; Nathanson, KL; Cortessis, [No Value; Easton, DF; Bishop, DT; Stratton, MR; Rapley, EA

    2006-01-01

    A family history of disease is a strong risk factor for testicular germ cell tumour (TGCT). In order to identify the location of putative TGCT susceptibility gene(s) we conducted a linkage search in 237 pedigrees with two or more cases of TGCT. One hundred and seventy-nine pedigrees were evaluated g

  11. The Organization and the Person: Final Report of the Individual-Organizational Linkages Project.

    Science.gov (United States)

    Porter, Lyman W.; Dubin, Robert

    What factors affect the attachment of employees to their work and work organization? What are the consequences of attachment or lack of it? The report summarizes the broad findings of a long-term research project designed to examine attitudinal and behavioral aspects of individual-organization linkages, conceived in two broad categories--the acts…

  12. Genome-wide linkage scan for the metabolic syndrome: the GENNID study.

    Science.gov (United States)

    Edwards, Karen L; Hutter, Carolyn M; Wan, Jia Yin; Kim, Helen; Monks, Stephanie A

    2008-07-01

    In the United States, the metabolic syndrome (MetS) constitutes a major public health problem with over 47 million persons meeting clinical criteria for MetS. Numerous studies have suggested genetic susceptibility to MetS. The goals of this study were (i) to identify susceptibility loci for MetS in well-characterized families with type 2 diabetes (T2D) in four ethnic groups and (ii) to determine whether evidence for linkage varies across the four groups. The GENNID study (Genetics of NIDDM) is a multicenter study established by the American Diabetes Association in 1993 and comprises a comprehensive, well-characterized resource of T2D families from four ethnic groups (whites, Mexican Americans, African Americans, and Japanese Americans). Principal component factor analysis (PCFA) was used to define quantitative phenotypes of the MetS. Variance components linkage analysis was conducted using microsatellite markers from a 10-cM genome-wide linkage scan, separately in each of the four ethnic groups. Three quantitative MetS factors were identified by PCFA and used as phenotypes for MetS: (i) a weight/waist factor, (ii) a blood pressure factor, and (iii) a lipid factor. Evidence for linkage to each of these factors was observed. For each ethnic group, our results suggest that several regions harbor susceptibility genes for the MetS. The strongest evidence for linkage for MetS phenotypes was observed on chromosome 2 (2q12.1-2q13) in the white sample and on chromosome 3 (3q26.1-3q29) in the Mexican-American sample. In conclusion, the results suggest that several regions harbor MetS susceptibility genes and that heterogeneity may exist across groups.

  13. Candidate region linkage analysis in twins discordant or concordant for depression symptomatology

    DEFF Research Database (Denmark)

    Christiansen, Lene; Tan, Q; Kruse, T A

    2009-01-01

    Genetic risk factors contribute considerably to both clinical affective disorders and subsyndromal mood level. There is moreover evidence to suggest that the genetic basis of bipolar disorder and unipolar depression overlap to some extent, and several linkage analyses have suggested evidence...... for a common susceptibility locus in affective disorders on chromosome 12q24. In this study we investigated the chromosome 12 candidate region for linkage to the mean level of depression symptomatology, over a 10-year follow-up, using a highly informative sample of concordant and discordant twin pairs selected...

  14. JLIN: A java based linkage disequilibrium plotter

    Directory of Open Access Journals (Sweden)

    McCaskie Pamela A

    2006-02-01

    Full Text Available Abstract Background A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly used to examine and compare markers across increasingly large datasets. Visualisation techniques are becoming essential to analyse the ever-growing volume of data and results available with any given analysis. Results JLIN (Java LINkage disequilibrium plotter is a software package designed for customisable, intuitive visualisation of Linkage Disequilibrium (LD across all common computing platforms. Customisation allows the user to choose particular visualisations, statistical measures and measurement ranges. JLIN also allows the user to export images of the LD visualisation in several common document formats. Conclusion JLIN allows the user to visually compare and contrast the results of a range of statistical measures on the input dataset(s. These measures include the commonly used D' and r2 statistics and empirical p-values. JLIN has a number of unique and novel features that improve on existing LD visualisation tools.

  15. Methods for genetic linkage analysis using trisomies

    Energy Technology Data Exchange (ETDEWEB)

    Feingold, E. [Emory Univ. School of Public Health, Atlanta, GA (United States); Lamb, N.E.; Sherman, S.L. [Emory Univ., Atlanta, GA (United States)

    1995-02-01

    Certain genetic disorders are rare in the general population, but more common in individuals with specific trisomies. Examples of this include leukemia and duodenal atresia in trisomy 21. This paper presents a linkage analysis method for using trisomic individuals to map genes for such traits. It is based on a very general gene-specific dosage model that posits that the trait is caused by specific effects of different alleles at one or a few loci and that duplicate copies of {open_quotes}susceptibility{close_quotes} alleles inherited from the nondisjoining parent give increased likelihood of having the trait. Our mapping method is similar to identity-by-descent-based mapping methods using affected relative pairs and also to methods for mapping recessive traits using inbred individuals by looking for markers with greater than expected homozygosity by descent. In the trisomy case, one would take trisomic individuals and look for markers with greater than expected homozygosity in the chromosomes inherited from the nondisjoining parent. We present statistical methods for performing such a linkage analysis, including a test for linkage to a marker, a method for estimating the distance from the marker to the trait gene, a confidence interval for that distance, and methods for computing power and sample sizes. We also resolve some practical issues involved in implementing the methods, including how to use partially informative markers and how to test candidate genes. 20 refs., 5 figs., 1 tab.

  16. Model-based methods for linkage analysis.

    Science.gov (United States)

    Rice, John P; Saccone, Nancy L; Corbett, Jonathan

    2008-01-01

    The logarithm of an odds ratio (LOD) score method originated in a seminal article by Newton Morton in 1955. The method is broadly concerned with issues of power and the posterior probability of linkage, ensuring that a reported linkage has a high probability of being a true linkage. In addition, the method is sequential so that pedigrees or LOD curves may be combined from published reports to pool data for analysis. This approach has been remarkably successful for 50 years in identifying disease genes for Mendelian disorders. After discussing these issues, we consider the situation for complex disorders where the maximum LOD score statistic shares some of the advantages of the traditional LOD score approach, but is limited by unknown power and the lack of sharing of the primary data needed to optimally combine analytic results. We may still learn from the LOD score method as we explore new methods in molecular biology and genetic analysis to utilize the complete human DNA sequence and the cataloging of all human genes.

  17. Structural synthesis of linkages for quadruped bio-robot legs

    Science.gov (United States)

    Antonescu, O.; Robu, C.; Antonescu, P.

    2016-08-01

    The paper presents a few kinematic schemes of planar mechanisms with bars (linkages) used as part of the quadruped robot legs. The Dunshee linkage having only four elements as crank-rocker mechanism is analyzed. Further, the Klann linkage, which is accomplished by amplifying the crank-rocker mechanism with a dyadic kinematic chain, is also presented. More than that, the Jansen linkage, which is obtained by extending and amplifying the crank-rocker mechanism with two dyadic kinematic chains, is also analyzed. At the end of the paper, the authors present a novel linkage application consisting of a quadric kinematic chain.

  18. Dependency of Electrochemical Performances of Silicon Lithium-Ion Batteries on Glycosidic Linkages of Polysaccharide Binders.

    Science.gov (United States)

    Yoon, Da-Eun; Hwang, Chihyun; Kang, Na-Ri; Lee, Ungju; Ahn, Dongjoon; Kim, Ju-Young; Song, Hyun-Kon

    2016-02-17

    Molecular structures of polysaccharide binders determining mechanical properties were correlated to electrochemical performances of silicon anodes for lithium-ion batteries. Glycosidic linkages (α and β) and side chains (-COOH and -OH) were selected and proven as the major factors of the molecular structures. Three different single-component polysaccharides were compared: pectin for α-linkages versus carboxylic methyl cellulose (CMC) for β-linkages from the linkage's standpoint, and pectin as a COOH-containing polymer and amylose as its non-COOH counterpart from the side chain's standpoint. Pectin was remarkably superior to CMC and amylose in cyclability and rate capability of battery cells based on silicon anodes. The pectin binder allowed volume expansion of silicon electrodes with keeping high porosity during lithiation due to the elastic nature caused by the chair-to-boat conformation in α-linkages of its backbone. Physical integrity of pectin-based electrodes was not challenged during repeated lithiation/delithiation cycles without crack development that was observed in rigid CMC-based electrodes. Covalent bonds formed between carboxylic side chains of pectin and silicon surface oxide prevented active silicon mass from being detached away from electric pathways. However, hydrogen bonds between hydroxyl side chains of amylose and silicon surface oxide were not strong enough to keep the silicon mass electrochemically active after cyclability tests.

  19. Cost Linkages Transmit Volatility Across Markets

    DEFF Research Database (Denmark)

    Nguyen, Daniel Xuyen; Schaur, Georg

    to link the domestic and export supply costs. This theoretical contribution has two new implications for the exporting firm. First, the demand volatility in the foreign market now directly affects the firm's domestic sales volatility. Second, firms hedge domestic demand volatility with exports. The model...

  20. Exploiting Linkage Information and Problem-Specific Knowledge in Evolutionary Distribution Network Expansion Planning.

    Science.gov (United States)

    Luong, Ngoc Hoang; Poutré, Han La; Bosman, Peter A N

    2017-04-07

    This article tackles the Distribution Network Expansion Planning (DNEP) problemthat has to be solved by distribution network operators to decide which, where, and/or when enhancements to electricity networks should be introduced to satisfy the future power demands. Because of many real-world details involved, the structure of the problem is not exploited easily using mathematical programming techniques, for which reason we consider solving this problem with evolutionary algorithms (EAs). We compare three types of EAs for optimizing expansion plans: the classic genetic algorithm (GA), the estimation-of-distribution algorithm (EDA), and the Gene-pool Optimal Mixing Evolutionary Algorithm (GOMEA). Not fully knowing the structure of the problem, we study the effect of linkage learning through the use of three linkage models: univariate, marginal product, and linkage tree. We furthermore experiment with the impact of incorporating different levels of problem-specific knowledge in the variation operators. Experiments show that the use of problem-specific variation operators is far more important for the classic GA to find high-quality solutions. In all EAs, the marginal product model and its linkage learning procedure have difficulty in capturing and exploiting the DNEP problemstructure. GOMEA, especiallywhen combined with the linkage tree structure, is found to have the most robust performance by far, even when an out-of-the-box variant is used that does not exploit problem-specific knowledge. Based on experiments, we suggest that when selecting optimization algorithms for power system expansion planning problems, EAs that have the ability to effectively model and efficiently exploit problem structures, such as GOMEA, should be given priority, especially in the case of black-box or grey-box optimization.

  1. HLA region excluded by linkage analyses of early onset periodontitis

    Energy Technology Data Exchange (ETDEWEB)

    Sun, C.; Wang, S.; Lopez, N.

    1994-09-01

    Previous studies suggested that HLA genes may influence susceptibility to early-onset periodontitis (EOP). Segregation analyses indicate that EOP may be due to a single major gene. We conducted linkage analyses to assess possible HLA effects on EOP. Fifty families with two or more close relatives affected by EOP were ascertained in Virginia and Chile. A microsatellite polymorphism within the HLA region (at the tumor necrosis factor beta locus) was typed using PCR. Linkage analyses used a donimant model most strongly supported by previous studies. Assuming locus homogeneity, our results exclude a susceptibility gene within 10 cM on either side of our marker locus. This encompasses all of the HLA region. Analyses assuming alternative models gave qualitatively similar results. Allowing for locus heterogeneity, our data still provide no support for HLA-region involvement. However, our data do not statistically exclude (LOD <-2.0) hypotheses of disease-locus heterogeneity, including models where up to half of our families could contain an EOP disease gene located in the HLA region. This is due to the limited power of even our relatively large collection of families and the inherent difficulties of mapping genes for disorders that have complex and heterogeneous etiologies. Additional statistical analyses, recruitment of families, and typing of flanking DNA markers are planned to more conclusively address these issues with respect to the HLA region and other candidate locations in the human genome. Additional results for markers covering most of the human genome will also be presented.

  2. Ubiquitin Chain Editing Revealed By Polyubiquitin Linkage-Specific Antibodies

    Energy Technology Data Exchange (ETDEWEB)

    Newton, K.; Matsumoto, M.L.; Wertz, I.E.; Kirkpatrick, D.S.; Lill, J.R.; Tan, J.; Dugger, D.; Gordon, N.; Sidhu, S.S.; Fellouse, F.A.; Komuves, L.; French, D.M.; Ferrando, R.E.; Lam, C.; Compaan, D.; Yu, C.; Bosanac, I.; Hymowitz, S.G.; Kelley, R.F.; Dixit, V.M.

    2009-05-22

    Posttranslational modification of proteins with polyubiquitin occurs in diverse signaling pathways and is tightly regulated to ensure cellular homeostasis. Studies employing ubiquitin mutants suggest that the fate of polyubiquitinated proteins is determined by which lysine within ubiquitin is linked to the C terminus of an adjacent ubiquitin. We have developed linkage-specific antibodies that recognize polyubiquitin chains joined through lysine 63 (K63) or 48 (K48). A cocrystal structure of an anti-K63 linkage Fab bound to K63-linked diubiquitin provides insight into the molecular basis for specificity. We use these antibodies to demonstrate that RIP1, which is essential for tumor necrosis factor-induced NF-{kappa}B activation, and IRAK1, which participates in signaling by interleukin-1{beta} and Toll-like receptors, both undergo polyubiquitin editing in stimulated cells. Both kinase adaptors initially acquire K63-linked polyubiquitin, while at later times K48-linked polyubiquitin targets them for proteasomal degradation. Polyubiquitin editing may therefore be a general mechanism for attenuating innate immune signaling.

  3. The effects of selection on linkage analysis for quantitative traits.

    Science.gov (United States)

    Mackinnon, M J; Georges, M A

    1992-12-01

    The effects of within-sample selection on the outcome of analyses detecting linkage between genetic markers and quantitative traits were studied. It was found that selection by truncation for the trait of interest significantly reduces the differences between marker genotype means thus reducing the power to detect linked quantitative trait loci (QTL). The size of this reduction is a function of proportion selected, the magnitude of the QTL effect, recombination rate between the marker locus and the QTL, and the allele frequency of the QTL. Proportion selected was the most influential of these factors on bias, e.g., for an allele substitution effect of one standard deviation unit, selecting the top 80%, 50% or 20% of the population required 2, 6 or 24 times the number of progeny, respectively, to offset the loss of power caused by this selection. The effect on power was approximately linear with respect to the size of gene effect, almost invariant to recombination rate, and a complex function of QTL allele frequency. It was concluded that experimental samples from animal populations which have been subjected to even minor amounts of selection will be inefficient in yielding information on linkage between markers and loci influencing the quantitative trait under selection.

  4. Optimizing Opt-Out Consent for Record Linkage

    Directory of Open Access Journals (Sweden)

    Das Marcel

    2014-09-01

    Full Text Available This article reports on a study testing the effects of different ways of administering an opt-out consent for record linkage in a probability-based Internet panel. First, we conducted cognitive interviews to explore reactions to a draft version of the opt-out consent text. Second, we conducted a two-factor experiment to test the effects of content manipulations and mode. The results indicate that the way in which respondents were informed did not have much effect on opting out. Results from a follow-up survey on attitudes regarding privacy, confidentiality, and trust, along with knowledge questions about the process of linking, showed no evidence that presenting the opt-out consent statement makes respondents more concerned about privacy. Knowledge about the aspects of record linkage is generally not high. When looking at long-term effects of sending an opt-out consent statement, we found no evidence that this leads to higher attrition or lower participation rates.

  5. Health governance: principal-agent linkages and health system strengthening.

    Science.gov (United States)

    Brinkerhoff, Derick W; Bossert, Thomas J

    2014-09-01

    Governance is increasingly recognized as an important factor in health system performance, yet conceptually and practically it remains poorly understood and subject to often vague and competing notions of both what its role is and how to address its weaknesses. This overview article for the symposium on health governance presents a model of health governance that focuses on the multiplicity of societal actors in health systems, the distribution of roles and responsibilities among them and their ability and willingness to fulfil these roles and responsibilities. This focus highlights the principal-agent linkages among actors and the resulting incentives for good governance and health system performance. The discussion identifies three disconnects that constitute challenges for health system strengthening interventions that target improving governance: (1) the gap between the good governance agenda and existing capacities, (2) the discrepancy between formal and informal governance and (3) the inattention to sociopolitical power dynamics. The article summarizes the three country cases in the symposium and highlights their governance findings: health sector reform in China, financial management of health resources in Brazilian municipalities and budget reform in hospitals in Lesotho. The concluding sections clarify how the three cases apply the model's principal-agent linkages and highlight the importance of filling the gaps remaining between problem diagnosis and the development of practical guidance that supports 'best fit' solutions and accommodates political realities in health systems strengthening.

  6. A genetic linkage map of Venturia inaequalis, the causal agent of apple scab

    Directory of Open Access Journals (Sweden)

    Harvey Nick G

    2009-08-01

    tool for investigating the genetics of important traits in V. inaequalis such as virulence factors, aggressiveness and mating type. The linkage map presented here represents a significant improvement over currently published maps for studying genome structure and organisation, and for mapping genes of economic importance on the V. inaequalis genome.

  7. Wireless Mesh Network Routing Under Uncertain Demands

    Science.gov (United States)

    Wellons, Jonathan; Dai, Liang; Chang, Bin; Xue, Yuan

    Traffic routing plays a critical role in determining the performance of a wireless mesh network. Recent research results usually fall into two ends of the spectrum. On one end are the heuristic routing algorithms, which are highly adaptive to the dynamic environments of wireless networks yet lack the analytical properties of how well the network performs globally. On the other end are the optimal routing algorithms that are derived from the optimization problem formulation of mesh network routing. They can usually claim analytical properties such as resource use optimality and throughput fairness. However, traffic demand is usually implicitly assumed as static and known a priori in these problem formulations. In contrast, recent studies of wireless network traces show that the traffic demand, even being aggregated at access points, is highly dynamic and hard to estimate. Thus, to apply the optimization-based routing solution in practice, one must take into account the dynamic and uncertain nature of wireless traffic demand. There are two basic approaches to address the traffic uncertainty in optimal mesh network routing (1) predictive routing that infers the traffic demand with maximum possibility based in its history and optimizes the routing strategy based on the predicted traffic demand and (2) oblivious routing that considers all the possible traffic demands and selects the routing strategy where the worst-case network performance could be optimized. This chapter provides an overview of the optimal routing strategies for wireless mesh networks with a focus on the above two strategies that explicitly consider the traffic uncertainty. It also identifies the key factors that affect the performance of each routing strategy and provides guidelines towards the strategy selection in mesh network routing under uncertain traffic demands.

  8. Rural–Urban Linkages and Sustainable Regional Development: The Role of Entrepreneurs in Linking Peripheries and Centers

    Directory of Open Access Journals (Sweden)

    Heike Mayer

    2016-08-01

    Full Text Available Urban and rural areas differ in economic, social and environmental terms. Due to the diverging dynamics in urban and rural areas, the social and economic distance between them might increase in the future even more. Rural entrepreneurs with linkages to urban areas are able to bridge the rural–urban divide by accessing some of the urban features, such as knowledge and markets, while at the same time profiting from the advantages of their peripheral location. This paper highlights exploratory results from qualitative interviews with rural entrepreneurs, and we illustrate entrepreneurial linkages to urban centers. The interview data show that rural entrepreneurs with rural–urban linkages develop sensibility for core market demands and trends, they valuate rural assets, and they combine rural and urban sources of knowledge for innovation. Through their entrepreneurial activity, rural entrepreneurs with linkages to urban areas might constitute an opposite force to polarizing concentration of economic activities in cities. Hence, rural entrepreneurs with urban linkages might contribute to sustainable economic relationships between urban and rural areas.

  9. Percent Errors in the Estimation of Demand for Secondary Items.

    Science.gov (United States)

    1985-11-01

    percent errors, and the program change factor (PCF) to predict item demana during the procurement *’ leadtime (PROLT) ior the item. The PCF accounts for...type of demand it was. It may"-- have been demanded over two years ago or it may nave been a non-recurring demana . Since CC b only retains two years of...observed distributions could be compared with negative binomial distributions. For each item the computed ratio of actual demana to expected demand was

  10. Information Demand Pattern for Teams

    Directory of Open Access Journals (Sweden)

    Dirk Stamer

    2016-04-01

    Full Text Available Modern organizations face the challenge of having to manage an increasing amount of information. The resulting information overload leads more and more to problems in decision making with potentially negative economic consequences. Decision-makers and knowledge intensive workers are especially affected. To address this problem, information demand patterns were proposed which capture organizational knowledge about the information demand of single roles. This work extends the concept of information demand patterns from single roles to teams. Using the knowledge intensive field of project management, the paper shows how to apply the concept of information demand patterns for a whole team. The contributions of this work are (1 the methodical approach to develop information demand patterns for teams, (2 an actual information demand pattern for a steering committee in the context of project management, (3 reflections on the differences between role patterns and team patterns.

  11. An exact management method for demand driven, industrial operations

    OpenAIRE

    Puikko, J. (Janne)

    2010-01-01

    Abstract The framing into demand driven operations is because of the operations research modelling approach. The modelling approach requires continuous regressors and an independent response factor. The demand as an operating factor is considered as independent response factor in relation to the continuous regressors. The method validation is made along several longitudinal case studies to cover local, global and international industrial operations. The examined operational scope is from c...

  12. 我国机动车辆保险市场发展的需求拉动因素研究%Research on Demands-driven Factors for the Development of the Motor Insurance Market in China

    Institute of Scientific and Technical Information of China (English)

    刘璐; 张博江

    2012-01-01

    近些年来,我国机动车辆保险市场呈现出迅速扩张的势头,车险成为提升最快的险种之一。目前作为财产保险的第一大险种——机动车辆保险,在促进财产保险业发展的同时也成为整个保险业的重大影响因素之一。本文在对我国机动车辆保险市场发展现状进行阐述的基础上,分析各个因素对于机动车辆保险市场的影响。根据影响需求的因素分析并结合计量经济学回归模型,提出相关的政策与建议从而发掘机动车辆保险市场需求潜力,并根据模型得出的结论对未来几年我国机动车辆保险的保费收入做出相应的预测。%The motor vehicle insurance market in China has been expanding rapidly in recent years and has become one of the lines of business with the fastest growth rate. As the biggest insurance business of property insur- ance, motor vehicle insurance has greatly enhanced the development of the property insurance and is also one of the major drivers for the development of the whole insurance industry. This paper analyzed various factors affecting the motor vehicle insurance market following an elaboration on the current situation of motor vehicle insurance market in China. Based on the factors influencing motor vehicle insurance demands and in combination with the measurement economics model, the paper tried to come up with some advice and policy suggestions to further exploit the market potential and make a reasonable prediction for the premium income of motor vehicle insurance in China in the coming years according to the results of the analysis.

  13. North American oil demand outlook

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, M.B. [National Economic Research Associates, White Plains, NY (United States)

    1995-11-01

    An understanding of the relationship of economic growth and potential petroleum product demand is needed to forecast the potential for North American oil demand growth as well as knowledge of world supply and price. The bullish expectations for economic growth in the US and Canada auger well for North American refiners and marketeers. The growth in world economic output forecast, however, means a larger oil demand and an increase in OPEC`s pricing power. Such price increases could depress North American oil demand growth. (author)

  14. An integrated communications demand model

    Science.gov (United States)

    Doubleday, C. F.

    1980-11-01

    A computer model of communications demand is being developed to permit dynamic simulations of the long-term evolution of demand for communications media in the U.K. to be made under alternative assumptions about social, economic and technological trends in British Telecom's business environment. The context and objectives of the project and the potential uses of the model are reviewed, and four key concepts in the demand for communications media, around which the model is being structured are discussed: (1) the generation of communications demand; (2) substitution between media; (3) technological convergence; and (4) competition. Two outline perspectives on the model itself are given.

  15. Egalitarianism Policy and Effective Demand under Globalization

    Directory of Open Access Journals (Sweden)

    Taro ABE

    2015-09-01

    Full Text Available Abstract. The study examines egalitarianism policies in terms of the relationship between labor and capital and extends the model developed by the economist Bowles. We introduce the demand factor to the Bowles model (2012, which discussed the effectiveness of the income and asset redistribution policies in a global economy. The improvement of productivity and the decrease in the ratio of monitoring labor through asset-based redistribution increase the real wage rate because of its lure for foreign capital. At this point in the Bowles model, the labor supply increases and then employment increases. In contrast, in our model, with the addition of the demand factor, the improvement of productivity increases employment, but the decrease in monitoring labor does not always increase employment as both demand and supply increase. This means that asset-based redistribution in a global economy is not always effective.Keywords. Egalitarianism, Redistribution, Effective demand, Globalization.JEL. E12, F60, J80, J88.

  16. Not all job demands are equal: differentiating job hindrances and job challenges in the job demands-resources model

    OpenAIRE

    Van den Broeck, Anja; De Cuyper, Nele; De Witte, Hans; Vansteenkiste, Maarten

    2010-01-01

    This study aimed to integrate the differentiation between two types of job demands, as made in previous studies, in the Job-Demands Resources (JD-R) model. Specifically, this study aimed to examine empirically whether the differentiation between job hindrances and job challenges, next to the category of job resources, accounts for the unexpected positive relationships between particular types of job demands (e.g., workload) and employees' work engagement. Results of confirmatory factor analys...

  17. Population-environment linkages in international law

    Energy Technology Data Exchange (ETDEWEB)

    Babor, D.D.M.

    1999-03-31

    This article explores population-environment linkages both within developed and developing nations, and considers the consequences of a population growth rate which, as one hectare of arable land is simultaneously lost or destroyed, currently results in eight live births every three seconds. In order to better comprehend the forces governing their perceptions, Part 1 of this article will discuss eight interactive variables which inform decision-making. Part 2 will examine the existence of legal duties under international law to limit or constrain the level of consumption and the right to freely reproduce, particularly as applicable in states considered free of a population problem.

  18. LINKAGES FOR QUADRUPED BIO-ROBOT WALKING

    Directory of Open Access Journals (Sweden)

    Ovidiu ANTONESCU

    2015-12-01

    Full Text Available This paper analyses the Jansen mechanism. It then presents a few pictures of a mobile quadruped robot, which will help to describe how the robot moves. We take into consideration the kinematic scheme of the spatial mechanism with bars (spatial linkage, which is used for each of the four robot legs. Each leg mechanism is driven by two rotate brushless actuators that include a spur gear low-ratio transmission. By means of analyzing the kinematic scheme, the spatial mechanism mobility that operates in both horizontal and vertical plane is calculated

  19. A genome-wide linkage study of individuals with high scores on NEO personality traits.

    Science.gov (United States)

    Amin, N; Schuur, M; Gusareva, E S; Isaacs, A; Aulchenko, Y S; Kirichenko, A V; Zorkoltseva, I V; Axenovich, T I; Oostra, B A; Janssens, A C J W; van Duijn, C M

    2012-10-01

    The NEO-Five-Factor Inventory divides human personality traits into five dimensions: neuroticism, extraversion, openness, conscientiousness and agreeableness. In this study, we sought to identify regions harboring genes with large effects on the five NEO personality traits by performing genome-wide linkage analysis of individuals scoring in the extremes of these traits (>90th percentile). Affected-only linkage analysis was performed using an Illumina 6K linkage array in a family-based study, the Erasmus Rucphen Family study. We subsequently determined whether distinct, segregating haplotypes found with linkage analysis were associated with the trait of interest in the population. Finally, a dense single-nucleotide polymorphism genotyping array (Illumina 318K) was used to search for copy number variations (CNVs) in the associated regions. In the families with extreme phenotype scores, we found significant evidence of linkage for conscientiousness to 20p13 (rs1434789, log of odds (LOD)=5.86) and suggestive evidence of linkage (LOD >2.8) for neuroticism to 19q, 21q and 22q, extraversion to 1p, 1q, 9p and12q, openness to 12q and 19q, and agreeableness to 2p, 6q, 17q and 21q. Further analysis determined haplotypes in 21q22 for neuroticism (P-values = 0.009, 0.007), in 17q24 for agreeableness (marginal P-value = 0.018) and in 20p13 for conscientiousness (marginal P-values = 0.058, 0.038) segregating in families with large contributions to the LOD scores. No evidence for CNVs in any of the associated regions was found. Our findings imply that there may be genes with relatively large effects involved in personality traits, which may be identified with next-generation sequencing techniques.

  20. the determinants of demand for public transport services in kumasi ...

    African Journals Online (AJOL)

    dmosman.admin

    The objective of the study was to establish the major factors influencing demand as well as de- velop a demand model for urban passenger transport services in Kumasi, Ghana. .... of higher-quality services (air-conditioned, seat ... age of the vehicles within the industry is 18 ...... and Managing the Development of Kumasi,.

  1. A Conservative Meta-Analysis of Linkage and Linkage-Association Studies of Developmental Dyslexia

    Science.gov (United States)

    Grigorenko, Elena L.

    2005-01-01

    Linkage studies of complex phenotypes such as reading ability/disability (developmental dyslexia or reading disorder) and related componential processes, where the effects attributable to individual genes appear to be modest, are critically dependent on the nature and composition of the samples and the phenotypes analyzed. Thus, it might be…

  2. Demand Response in Smart Grids

    DEFF Research Database (Denmark)

    Hansen, Jacob; Knudsen, Jesper Viese; Annaswamy, Anuradha M.

    2014-01-01

    In recent decades, moves toward higher integration of Renewable Energy Resources have called for fundamental changes in both the planning and operation of the overall power grid. One such change is the incorporation of Demand Response (DR), the process by which consumers can adjust their demand i...

  3. Job demands-resources model

    NARCIS (Netherlands)

    A.B. Bakker (Arnold); E. Demerouti (Eva)

    2013-01-01

    markdownabstract* The question of what causes job stress and what motivates people has received a lot of research attention during the past five decades. In this paper, we discuss Job Demands-Resources (JD-R) theory, which represents an extension of the Job Demands-Resources model (Bakker &

  4. Technical Workers in Great Demand

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The Labor and Social Security Ministry conducted a survey on 81 labor markets across China in the second quarter of this year, the results of which showed that the demand for technical workers, especially those of middle and senior titles, far outnumbers the supply.The survey shows that the demand/supply

  5. Job demands-resources model

    NARCIS (Netherlands)

    A.B. Bakker (Arnold); E. Demerouti (Eva)

    2013-01-01

    markdownabstract* The question of what causes job stress and what motivates people has received a lot of research attention during the past five decades. In this paper, we discuss Job Demands-Resources (JD-R) theory, which represents an extension of the Job Demands-Resources model (Bakker & Demerout

  6. CAREER GUIDE FOR DEMAND OCCUPATIONS.

    Science.gov (United States)

    LEE, E.R.; WELCH, JOHN L.

    THIS PUBLICATION UPDATES THE "CAREER GUIDE FOR DEMAND OCCUPATIONS" PUBLISHED IN 1959 AND PROVIDES COUNSELORS WITH INFORMATION ABOUT OCCUPATIONS IN DEMAND IN MANY AREAS WHICH REQUIRE PREEMPLOYMENT TRAINING. IT PRESENTS, IN COLUMN FORM, THE EDUCATION AND OTHER TRAINING USUALLY REQUIRED BY EMPLOYERS, HIGH SCHOOL SUBJECTS OF PARTICULAR PERTINENCE TO…

  7. Job demands-resources model

    NARCIS (Netherlands)

    A.B. Bakker (Arnold); E. Demerouti (Eva)

    2013-01-01

    markdownabstract* The question of what causes job stress and what motivates people has received a lot of research attention during the past five decades. In this paper, we discuss Job Demands-Resources (JD-R) theory, which represents an extension of the Job Demands-Resources model (Bakker & Demerout

  8. Methods for genetic linkage analysis using trisomies

    Energy Technology Data Exchange (ETDEWEB)

    Feingold, E.; Lamb, N.E.; Sherman, S.L. [Emory Univ., Atlanta, GA (United States)

    1994-09-01

    Certain genetic disorders (e.g. congenital cataracts, duodenal atresia) are rare in the general population, but more common in people with Down`s syndrome. We present a method for using individuals with trisomy 21 to map genes for such traits. Our methods are analogous to methods for mapping autosomal dominant traits using affected relative pairs by looking for markers with greater than expected identity-by-descent. In the trisomy case, one would take trisomic individuals and look for markers with greater than expected reduction to homozygosity in the chromosomes inherited form the non-disjoining parent. We present statistical methods for performing such a linkage analysis, including a test for linkage to a marker, a method for estimating the distance from the marker to the gene, a confidence interval for that distance, and methods for computing power and sample sizes. The methods are described in the context of gene-dosage model for the etiology of the disorder, but can be extended to other models. We also resolve some practical issues involved in implementing the methods, including how to use partially informative markers, how to test candidate genes, and how to handle the effect of reduced recombination associated with maternal meiosis I non-disjunction.

  9. Automated Demand Response and Commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Piette, Mary Ann; Watson, David S.; Motegi, Naoya; Bourassa, Norman

    2005-04-01

    This paper describes the results from the second season of research to develop and evaluate the performance of new Automated Demand Response (Auto-DR) hardware and software technology in large facilities. Demand Response (DR) is a set of activities to reduce or shift electricity use to improve the electric grid reliability and manage electricity costs. Fully-Automated Demand Response does not involve human intervention, but is initiated at a home, building, or facility through receipt of an external communications signal. We refer to this as Auto-DR. The evaluation of the control and communications must be properly configured and pass through a set of test stages: Readiness, Approval, Price Client/Price Server Communication, Internet Gateway/Internet Relay Communication, Control of Equipment, and DR Shed Effectiveness. New commissioning tests are needed for such systems to improve connecting demand responsive building systems to the electric grid demand response systems.

  10. Accuracy analysis of TDRSS demand forecasts

    Science.gov (United States)

    Stern, Daniel C.; Levine, Allen J.; Pitt, Karl J.

    1994-01-01

    This paper reviews Space Network (SN) demand forecasting experience over the past 16 years and describes methods used in the forecasts. The paper focuses on the Single Access (SA) service, the most sought-after resource in the Space Network. Of the ten years of actual demand data available, only the last five years (1989 to 1993) were considered predictive due to the extensive impact of the Challenger accident of 1986. NASA's Space Network provides tracking and communications services to user spacecraft such as the Shuttle and the Hubble Space Telescope. Forecasting the customer requirements is essential to planning network resources and to establishing service commitments to future customers. The lead time to procure Tracking and Data Relay Satellites (TDRS's) requires demand forecasts ten years in the future a planning horizon beyond the funding commitments for missions to be supported. The long range forecasts are shown to have had a bias toward underestimation in the 1991 -1992 period. The trend of underestimation can be expected to be replaced by overestimation for a number of years starting with 1998. At that time demand from new missions slated for launch will be larger than the demand from ongoing missions, making the potential for delay the dominant factor. If the new missions appear as scheduled, the forecasts are likely to be moderately underestimated. The SN commitment to meet the negotiated customer's requirements calls for conservatism in the forecasting. Modification of the forecasting procedure to account for a delay bias is, therefore, not advised. Fine tuning the mission model to more accurately reflect the current actual demand is recommended as it may marginally improve the first year forecasting.

  11. Genetic Mapping in Xenopus Laevis: Eight Linkage Groups Established

    OpenAIRE

    Graf, J. D.

    1989-01-01

    Inheritance of alleles at 29 electrophoretically detected protein loci and one pigment locus (albinism) was analyzed in Xenopus laevis by backcrossing multiply heterozygous individuals generated by intersubspecies hybridization. Pairwise linkage tests revealed eight classical linkage groups. These groups have been provisionally numbered from 1 to 8 in an arbitrarily chosen order. Linkage group 1 includes ALB-2 (albumin), ADH-1 (alcohol dehydrogenase), NP (nucleoside phosphorylase), and a(p) (...

  12. Model-free linkage analysis of a binary trait.

    Science.gov (United States)

    Xu, Wei; Bull, Shelley B; Mirea, Lucia; Greenwood, Celia M T

    2012-01-01

    Genetic linkage analysis aims to detect chromosomal regions containing genes that influence risk of specific inherited diseases. The presence of linkage is indicated when a disease or trait cosegregates through the families with genetic markers at a particular region of the genome. Two main types of genetic linkage analysis are in common use, namely model-based linkage analysis and model-free linkage analysis. In this chapter, we focus solely on the latter type and specifically on binary traits or phenotypes, such as the presence or absence of a specific disease. Model-free linkage analysis is based on allele-sharing, where patterns of genetic similarity among affected relatives are compared to chance expectations. Because the model-free methods do not require the specification of the inheritance parameters of a genetic model, they are preferred by many researchers at early stages in the study of a complex disease. We introduce the history of model-free linkage analysis in Subheading 1. Table 1 describes a standard model-free linkage analysis workflow. We describe three popular model-free linkage analysis methods, the nonparametric linkage (NPL) statistic, the affected sib-pair (ASP) likelihood ratio test, and a likelihood approach for pedigrees. The theory behind each linkage test is described in this section, together with a simple example of the relevant calculations. Table 4 provides a summary of popular genetic analysis software packages that implement model-free linkage models. In Subheading 2, we work through the methods on a rich example providing sample software code and output. Subheading 3 contains notes with additional details on various topics that may need further consideration during analysis.

  13. Adaptive Linkage Disequilibrium Between Two Esterase Loci of a Salamander

    Science.gov (United States)

    Webster, T. Preston

    1973-01-01

    In some populations of the salamander Plethodon cinereus, two polymorphic esterase loci are in linkage disequilibrium. Short-term stability of the linkage disequilibrium is demonstrated by an age class analysis. Long, perhaps very long, term stability is suggested by its distribution. This stability and concordant geographic variation in allelic frequencies imply selective origin and maintenance. Data on the frequencies of two color morphs suggest that formation of the linkage disequilibrium is dependent on the genetic background. Images PMID:4515614

  14. Are demand forecasting techniques applicable to libraries?

    OpenAIRE

    1984-01-01

    Examines the nature and limitations of demand forecasting, discuses plausible methods of forecasting demand for information, suggests some useful hints for demand forecasting and concludes by emphasizing unified approach to demand forecasting.

  15. Are demand forecasting techniques applicable to libraries?

    OpenAIRE

    M S Sridhar

    1984-01-01

    Examines the nature and limitations of demand forecasting, discuses plausible methods of forecasting demand for information, suggests some useful hints for demand forecasting and concludes by emphasizing unified approach to demand forecasting.

  16. 非政府组织的知识创新:需求、影响因素与路径%Knowledge Innovation of Non-Government Organization:Demands,Influencing Factors and Routes

    Institute of Scientific and Technical Information of China (English)

    裴乐

    2014-01-01

    在信息化浪潮下,知识的急速增长为组织发展带来了前所未有的机遇和挑战。知识因自身的独特性,不同于传统资源,有助于弥补非政府组织在资源配置和占有中的劣势。内外需求促使非政府组织准确分析知识、环境、组织因素,有效开展知识管理与创新,全面提升知识素质与能力。非政府组织可以从知识战略、组织学习、流程与机制、知识网络等方面,系统地实施知识创新活动,培养独特的核心知识,形成强大的竞争力,以更好的服务在社会转型和治理变革中实现价值。%Under the tide of informationization,the rapid growth of knowledge brings opportunities and challenges to organizations that did not exist before. The knowledge is different from traditional resources for its uniqueness, which helps remedy the disadvantages of non-government organizations in resources allocation and occupation. Demands from inside and outside impel non-government organizations to analyze factors of knowledge,environ-ment and organizations precisely,to develop knowledge management and innovation effectively,and to promote knowledge quality and ability totally. From aspects of knowledge strategy,organizing to learn,procedure,mecha-nism and knowledge network,non-government organizations can implement knowledge innovation activity system-atically to form unique core knowledge and powerful competence. Then,non-government organizations will realize value in social transformation and governance change by providing better and more services.

  17. Automated Generation of Kempe Linkage and Its Complexity

    Institute of Scientific and Technical Information of China (English)

    高小山; 朱长才

    1999-01-01

    It is a famous result of Kempe that a linkage can be designed to generate any given plane algebraic curve.In this paper,Kempe's result is improved to give a precise algorithm for generating Kempe linkage.We proved that for an algebraic plane curve of degrenn n,Kempe linkage uses at most O(n4) links.Efforts to implement a program which may generate Kempe linkage and simulation of the generation process of the plane curves are presented in the paper.

  18. Studi Demand Kereta Api Komuter Lawang - Kepanjen

    Directory of Open Access Journals (Sweden)

    Rendy Prasetya Rachman

    2013-09-01

    Full Text Available Dengan semakin pesatnya perkembangan perekonomian di propinsi Jawa Timur, khususnya di area Malang Raya mengakibatkan tingginya perpindahan orang maupun barang di area tersebut. Oleh karena itu, masyarakat membutuhkan alat transportasi yang dapat meningkatkan efisiensi dan efektifitas kegiatan mereka. Sehingga P.T. Kereta Api Indonesia Daerah Operasi VIII akan mengoperasikan kereta api komuter Lawang-Kepanjen. Akan tetapi saat ini sebagian besar pengguna kereta api komuter masih mengalami beberapa aspek negatif yaitu seringnya terjadi keterlambatan dan kapasitas tempat duduk yang masih kurang memadai sehingga mengurangi tingkat kenyamanan. Oleh karena itu, diperlukan analisa studi tentang demand kereta api komuter Lawang-Kepanjen. Dengan studi ini diharapkan agar para calon penumpang dapat memperoleh kenyamanan sesuai yang diharapkan. Pembahasan dalam Tugas Akhir ini adalah menganalisis demand yang ada, tarif yang diinginkan masyarakat, menganalisis kapasitas kendaraan dan load factor, serta menganalisis tingkat kenyamanan kendaraan. Sehingga perlu diadakan survei traffic counting, survei asal tujuan, dan survei stated preference dalam penulisan Tugas Akhir ini. Dalam perhitungan demand digunakan metode selisih cost dan metode ratio cost. Faktor yang berpengaruh dalam perhitungan demand ini antara lain asal-tujuan kepergian responden, waktu tempuh kepergian, biaya yang dikeluarkan, frekuensi kepergian, dan minat responden untuk pindah moda menggunakan kereta api komuter ini.Dari hasil analisa didapatkan besar demand untuk kereta api komuter Lawang-Kepanjen ini pada weekend untuk arus Kepanjen-Lawang sebesar 927 orang, dan arus Lawang-Kepanjen sebesar 746 orang. Sedangkan pada weekdays untuk arus Kepanjen-Lawang sebesar 1034 orang dan arus Lawang-Kepanjen sebesar 486 orang. Masyarakat calon pengguna potensial kereta komuter ini mayoritas lebih menyukai pilihan alternatif  tarif Rp 2.000 dengan waktu tempuh 90 menit. Load factor rata

  19. 武陵山片区老年人群养老模式需求调查及影响因素研究%Demand and Influencing Factors of EndoWment patterns of the Elderly in Wuling Mountain Areas

    Institute of Scientific and Technical Information of China (English)

    陈正英; 李金秀; 陈诗韵; 刘泽龙

    2014-01-01

    Objective To understand the pension demand of the elderly population among Wuling mountain areas and eXplore the influencing factors so as to provide reference for seeking the suitable pension service model. Methods A purposive sampling method was adopted. 2724 elderly people chosen from XiangXi Tujia and Miao Autonomous Prefecture,Xiushan county of Chongqing,Enˊshi of Hubei and Tongˊren of Guizhong were investigated by self - made questionnaire between July and Octo-ber,2013 about their general information,the present endowment status and their demand of endowment pattern. Results 1 105 (40.6%)chose community endowment;966(35.4%)chose family support;363(13.3%)chose old - age home;233 (8.6%)chose institution endowment;57(2.1%)chose others. The difference of choices was significant among the elderly who had different educational background,marital status,number of children,occupation before retirement,work willingness after retirement,financial situation satisfaction,health state and satisfaction,health eXpenditure payment,religious belief,daily liv-ing abilities(drug - taking,eating,clothes - dressing,tooth - brushing,hair - dressing,and call - making)( P<0.05). The number of children,health eXpenditure payment,religious belief,health state satisfaction,self-care abilities such as eat-ing and making calls were the significant influencing factors for the choices of endowment patterns(P<0.05). Conclusion The family pension and community endowment are the two main ideal pension model for the elderly in Wuling mountain area. The number of children,health eXpenditure payment,religious belief,health state satisfaction,self - care abilities such as eating and making calls influence the elderlyˊs choices. Family pension can not satisfy the elderlyˊs needs any more. They want a support-ive endowment service provided by the community. Therefore transition from the family pension to the community endowment will become the inevitable trend of the future development of

  20. Opportunities for Automated Demand Response in California Wastewater Treatment Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Aghajanzadeh, Arian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wray, Craig [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McKane, Aimee [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-08-30

    Previous research over a period of six years has identified wastewater treatment facilities as good candidates for demand response (DR), automated demand response (Auto-­DR), and Energy Efficiency (EE) measures. This report summarizes that work, including the characteristics of wastewater treatment facilities, the nature of the wastewater stream, energy used and demand, as well as details of the wastewater treatment process. It also discusses control systems and automated demand response opportunities. Furthermore, this report summarizes the DR potential of three wastewater treatment facilities. In particular, Lawrence Berkeley National Laboratory (LBNL) has collected data at these facilities from control systems, submetered process equipment, utility electricity demand records, and governmental weather stations. The collected data were then used to generate a summary of wastewater power demand, factors affecting that demand, and demand response capabilities. These case studies show that facilities that have implemented energy efficiency measures and that have centralized control systems are well suited to shed or shift electrical loads in response to financial incentives, utility bill savings, and/or opportunities to enhance reliability of service. In summary, municipal wastewater treatment energy demand in California is large, and energy-­intensive equipment offers significant potential for automated demand response. In particular, large load reductions were achieved by targeting effluent pumps and centrifuges. One of the limiting factors to implementing demand response is the reaction of effluent turbidity to reduced aeration at an earlier stage of the process. Another limiting factor is that cogeneration capabilities of municipal facilities, including existing power purchase agreements and utility receptiveness to purchasing electricity from cogeneration facilities, limit a facility’s potential to participate in other DR activities.

  1. Consumer demand and quality assurance

    DEFF Research Database (Denmark)

    Grunert, Klaus G; Wognum, Nel; Trienekens, Jacques

    2011-01-01

    Consumers differ in their demands, and this mau have implications for the type of supply chain governance that is most suitable for serving them. We present a segmentation of pork consumers in the EU based on their food-related lifestyles and demand for different pork products. We then present...... an inventory of pork chain governance and quality management systems, also resulting from a pan-European study, and attempt to match types of chains to consumer segments, arguing that the type of quality demanded by the consumers has implications especially for the quality management system governing the chain...

  2. Dietetics supply and demand: 2010-2020.

    Science.gov (United States)

    Hooker, Roderick S; Williams, James H; Papneja, Jesleen; Sen, Namrata; Hogan, Paul

    2012-03-01

    The Academy of Nutrition and Dietetics, in conjunction with the Commission on Dietetic Registration (CDR), invited The Lewin Group to undertake an analysis of the dietetics workforce. The purpose of the workforce study was to develop a model that can project the supply and demand for both registered dietitians (RDs) and dietetic technicians, registered (DTRs) (collectively referred to as CDR-credentialed dietetics practitioners) as the result of various key drivers of change. The research team was asked to quantify key market factors where possible and to project likely paths for the evolution of workforce supply and demand, as well as to assess the implications of the findings. This article drew on the survey research conducted by Readex Research and futurist organizations such as Signature i and Trend Spot Consulting. Furthermore, members of the Dietetics Workforce Demand Task Force were a source of institutional and clinical information relevant to the credentialed dietetics workforce--including their opinions and judgment of the current state of the health care market for dietetic services, its future state, and factors affecting it, which were useful and were integrated with the objective sources of data. The model is flexible and accommodates the variation in how RDs and DTRs function in diverse practice areas. For purposes of this study and model, the dietetics workforce is composed of RDs and DTRs. This report presents the results of this workforce study and the methodology used to calculate the projected dietetics workforce supply and demand. The projections are based on historical trends and estimated future changes. Key findings of the study included the following: • The average age of all CDR-credentialed dietetics practitioners in baseline supply (2010) is 44 years; approximately 96% are women. • Approximately 55% of CDR-credentialed dietetics practitioners work in clinical dietetics. • The annual growth rate of supply of CDR

  3. DEMAND CATEGORISATION, FORECASTING, AND INVENTORY CONTROL FOR INTERMITTENT DEMAND ITEMS

    Directory of Open Access Journals (Sweden)

    E. Babiloni

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: It is commonly assumed that intermittent demand appears randomly, with many periods without demand; but that when it does appear, it tends to be higher than unit size. Basic and well-known forecasting techniques and stock policies perform very poorly with intermittent demand, making new approaches necessary. To select the appropriate inventory management policy, it is important to understand the demand pattern for the items, especially when demand is intermittent. The use of a forecasting method designed for an intermittent demand pattern, such as Croston’s method, is required instead of a simpler and more common approach such as exponential smoothing. The starting point is to establish taxonomic rules to select efficiently the most appropriate forecasting and stock control policy to cope with thousands of items found in real environments. This paper contributes to the state of the art in: (i categorisation of the demand pattern; (ii methods to forecast intermittent demand; and (iii stock control methods for items with intermittent demand patterns. The paper first presents a structured literature review to introduce managers to the theoretical research about how to deal with intermittent demand items in both forecasting and stock control methods, and then it points out some research gaps for future development for the three topics.

    AFRIKAANSE OPSOMMING: Daar word algemeen aanvaar dat intermitterende vraag op toevalswyse voorkom, met verskeie periodes waar daar geen vraag is nie. Wanneer die vraag dan wel materialiseer, oorskry dit dikwels die eenheidsgrootte. Die bekende vooruitskattingstegnieke en voorraadbeleidstellings het min sukses waar intermitterende vraag voorkom, sodat nuwe benaderings nodig is om die problem aan te spreek. Om ‘n geskikte voorraadbestuur-beleid te selekteer, is dit noodsaaklik om die vraagpatroon van die items te verstaan, juis in gevalle van intermitterende patrone. Die gebruik van

  4. The Barley Chromosome 5 Linkage Map

    DEFF Research Database (Denmark)

    Jensen, J.; Jørgensen, Jørgen Helms

    1975-01-01

    The literature is surveyed for data on recombination between loci on chromosome 5 of barley; 13 loci fall into the category “mapped” loci, more than 20 into the category “associated” loci and nine into the category “loci once suggested to be on chromosome 5”. A procedure was developed...... for estimating a linkage map; it involves (1) transformation by the Kosambi mapping function of the available recombination percentages to additive map distances, (2) calculations of a set of map distances from the transformed recombination percentages by a maximum likelihood method in which all the available...... data are utilized jointly, and (3) omission of inconsistent data and determination of the most likely order of the loci. This procedure was applied to the 42 recombination percentages available for the 13 “mapped” loci. Due to inconsistencies 14 of the recombination percentages and, therefore, two...

  5. Quantifying landscape linkages among giant panda subpopulations in regional scale conservation.

    Science.gov (United States)

    Qi, Dunwu; Hu, Yibo; Gu, Xiaodong; Yang, Xuyi; Yang, Guang; Wei, Fuwen

    2012-06-01

    Understanding habitat requirements and identifying landscape linkages are essential for the survival of isolated populations of endangered species. Currently, some of the giant panda populations are isolated, which threatens their long-term survival, particularly in the Xiaoxiangling mountains. In the present study, we quantified niche requirements and then identified potential linkages of giant panda subpopulations in the most isolated region, using ecological niche factor analysis and a least-cost path model. Giant pandas preferred habitat with conifer forest and gentle slopes (>20 to ≤30°). Based on spatial distribution of suitable habitat, linkages were identified for the Yele subpopulation to 4 other subpopulations (Liziping, Matou, Xinmin and Wanba). Their lengths ranged from 15 to 54 km. The accumulated cost ranged from 693 to 3166 and conifer forest covered over 31%. However, a variety of features (e.g. major roads, human settlements and large unforested areas) might act as barriers along the linkages for giant panda dispersal. Our analysis quantified giant panda subpopulation connectivity to ensure long-term survival.

  6. Temperature Effect on Energy Demand

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Duk [Korea Energy Economics Institute, Euiwang (Korea)

    1999-03-01

    We provide various estimates of temperature effect for accommodating seasonality in energy demand, particularly natural gas demand. We exploit temperature response and monthly temperature distribution to estimate the temperature effect on natural gas demand. Both local and global smoothed temperature responses are estimated from empirical relationship between hourly temperature and hourly energy consumption data during the sample period (1990 - 1996). Monthly temperature distribution estimates are obtained by kernel density estimation from temperature dispersion within a month. We integrate temperature response and monthly temperature density over all the temperatures in the sample period to estimate temperature effect on energy demand. Then, estimates of temperature effect are compared between global and local smoothing methods. (author). 15 refs., 14 figs., 2 tabs.

  7. Consumer demand and quality assurance

    DEFF Research Database (Denmark)

    Grunert, Klaus G; Wognum, Nel; Trienekens, Jacques

    2011-01-01

    Consumers differ in their demands, and this mau have implications for the type of supply chain governance that is most suitable for serving them. We present a segmentation of pork consumers in the EU based on their food-related lifestyles and demand for different pork products. We then present an......, and that these implications are different for fresh meat and processed meat. The paper closes with a call for more collaboration between chain researchers and consumer researchers.......Consumers differ in their demands, and this mau have implications for the type of supply chain governance that is most suitable for serving them. We present a segmentation of pork consumers in the EU based on their food-related lifestyles and demand for different pork products. We then present...

  8. Saving Electricity and Demand Response

    Science.gov (United States)

    Yamaguchi, Nobuyuki

    A lot of people lost their lives in the tremendous earthquake in Tohoku region on March 11. A large capacity of electric power plants in TEPCO area was also damaged and large scale power shortage in this summer is predicted. In this situation, electricity customers are making great effort to save electricity to avoid planned outage. Customers take actions not only by their selves but also by some customers' cooperative movements. All actions taken actually are based on responses to request form the government or voluntary decision. On the other hand, demand response based on a financial stimulus is not observed as an actual behavior. Saving electricity by this demand response only discussed in the newspapers. In this commentary, the events regarding electricity-saving measure after this disaster are described and the discussions on demand response, especially a raise in power rate, are put into shapes in the context of this electricity supply-demand gap.

  9. Demand Response Spinning Reserve Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Joseph H.; Nelson-Hoffman, Janine; Torres, Carlos; Hirth,Scott; Yinger, Bob; Kueck, John; Kirby, Brendan; Bernier, Clark; Wright,Roger; Barat, A.; Watson, David S.

    2007-05-01

    The Demand Response Spinning Reserve project is a pioneeringdemonstration of how existing utility load-management assets can providean important electricity system reliability resource known as spinningreserve. Using aggregated demand-side resources to provide spinningreserve will give grid operators at the California Independent SystemOperator (CAISO) and Southern California Edison (SCE) a powerful, newtool to improve system reliability, prevent rolling blackouts, and lowersystem operating costs.

  10. Information Demand Pattern for Teams

    OpenAIRE

    Dirk Stamer; Kurt Sandkuhl; Veronika Zeiner

    2016-01-01

    Modern organizations face the challenge of having to manage an increasing amount of information. The resulting information overload leads more and more to problems in decision making with potentially negative economic consequences. Decision-makers and knowledge intensive workers are especially affected. To address this problem, information demand patterns were proposed which capture organizational knowledge about the information demand of single roles. This work extends the concept of informa...

  11. Fine mapping of multiple interacting quantitative trait loci using combined linkage disequilibrium and linkage information

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Quantitative trait loci (QTL) and their additive, dominance and epistatic effects play a critical role in complex trait variation. It is often infeasible to detect multiple interacting QTL due to main effects often being confounded by interaction effects.Positioning interacting QTL within a small region is even more difficult. We present a variance component approach nested in an empirical Bayesian method, which simultaneously takes into account additive, dominance and epistatic effects due to multiple interacting QTL. The covariance structure used in the variance component approach is based on combined linkage disequilibrium and linkage (LDL) information. In a simulation study where there are complex epistatic interactions between QTL, it is possible to simultaneously fine map interacting QTL using the proposed approach. The present method combined with LDL information can efficiently detect QTL and their dominance and epistatic effects, making it possible to simultaneously fine map main and epistatic QTL.

  12. Privacy-preserving record linkage on large real world datasets.

    Science.gov (United States)

    Randall, Sean M; Ferrante, Anna M; Boyd, James H; Bauer, Jacqueline K; Semmens, James B

    2014-08-01

    Record linkage typically involves the use of dedicated linkage units who are supplied with personally identifying information to determine individuals from within and across datasets. The personally identifying information supplied to linkage units is separated from clinical information prior to release by data custodians. While this substantially reduces the risk of disclosure of sensitive information, some residual risks still exist and remain a concern for some custodians. In this paper we trial a method of record linkage which reduces privacy risk still further on large real world administrative data. The method uses encrypted personal identifying information (bloom filters) in a probability-based linkage framework. The privacy preserving linkage method was tested on ten years of New South Wales (NSW) and Western Australian (WA) hospital admissions data, comprising in total over 26 million records. No difference in linkage quality was found when the results were compared to traditional probabilistic methods using full unencrypted personal identifiers. This presents as a possible means of reducing privacy risks related to record linkage in population level research studies. It is hoped that through adaptations of this method or similar privacy preserving methods, risks related to information disclosure can be reduced so that the benefits of linked research taking place can be fully realised. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. A fabrication process for electrostatic microactuators with integrated gear linkages

    NARCIS (Netherlands)

    Legtenberg, Rob; Berenschot, Erwin; Elwenspoek, Miko; Fluitman, Jan H.

    1997-01-01

    A surface micromachining process is presented which has been used to fabricate electrostatic microactuators. These microactuators are interconnected with each other and linked to other movable microstructures by integrated gear linkages. The gear linkages consist of rotational and linear gear struct

  14. Genome-wide linkage analysis for human longevity

    DEFF Research Database (Denmark)

    Beekman, Marian; Blanché, Hélène; Perola, Markus

    2013-01-01

    sibling pairs that have been enrolled in 15 study centers of 11 European countries as part of the Genetics of Healthy Aging (GEHA) project. In the joint linkage analyses, we observed four regions that show linkage with longevity; chromosome 14q11.2 (LOD = 3.47), chromosome 17q12-q22 (LOD = 2...

  15. Electrostatic microactuators with integrated gear linkages for mechanical power transmission

    NARCIS (Netherlands)

    Legtenberg, R.; Berenschot, J.W.; Elwenspoek, M.C.; Fluitman, J.H.J.

    1996-01-01

    In this paper a surface micromachining process is presented which has been used to fabricate electrostatic microactuators that are interconnected with each other and linked to other movable microstructures by integrated gear linkages. The gear linkages consist of rotational and linear gear structure

  16. Utility Sector Impacts of Reduced Electricity Demand

    Energy Technology Data Exchange (ETDEWEB)

    Coughlin, Katie

    2014-12-01

    This report presents a new approach to estimating the marginal utility sector impacts associated with electricity demand reductions. The method uses publicly available data and provides results in the form of time series of impact factors. The input data are taken from the Energy Information Agency's Annual Energy Outlook (AEO) projections of how the electric system might evolve in the reference case, and in a number of side cases that incorporate different effciency and other policy assumptions. The data published with the AEO are used to define quantitative relationships between demand-side electricity reductions by end use and supply-side changes to capacity by plant type, generation by fuel type and emissions of CO2, Hg, NOx and SO2. The impact factors define the change in each of these quantities per unit reduction in site electricity demand. We find that the relative variation in these impacts by end use is small, but the time variation can be significant.

  17. Disaggregating residential water demand for improved forecasts and decision making

    Science.gov (United States)

    Woodard, G.; Brookshire, D.; Chermak, J.; Krause, K.; Roach, J.; Stewart, S.; Tidwell, V.

    2003-04-01

    Residential water demand is the product of population and per capita demand. Estimates of per capita demand often are based on econometric models of demand, usually based on time series data of demand aggregated at the water provider level. Various studies have examined the impact of such factors as water pricing, weather, and income, with many other factors and details of water demand remaining unclear. Impacts of water conservation programs often are estimated using simplistic engineering calculations. Partly as a result of this, policy discussions regarding water demand management often focus on water pricing, water conservation, and growth control. Projecting water demand is often a straight-forward, if fairly uncertain process of forecasting population and per capita demand rates. SAHRA researchers are developing improved forecasts of residential water demand by disaggregating demand to the level of individuals, households, and specific water uses. Research results based on high-resolution water meter loggers, household-level surveys, economic experiments and recent census data suggest that changes in wealth, household composition, and individual behavior may affect demand more than changes in population or the stock of landscape plants, water-using appliances and fixtures, generally considered the primary determinants of demand. Aging populations and lower fertility rates are dramatically reducing household size, thereby increasing the number of households and residences for a given population. Recent prosperity and low interest rates have raised home ownership rates to unprecented levels. These two trends are leading to increased per capita outdoor water demand. Conservation programs have succeeded in certain areas, such as promoting drought-tolerant native landscaping, but have failed in other areas, such as increasing irrigation efficiency or curbing swimming pool water usage. Individual behavior often is more important than the household's stock of water

  18. Linkage studies of bipolar disorder with chromosome 18 markers.

    Science.gov (United States)

    Bowen, T; Kirov, G; Gill, M; Spurlock, G; Vallada, H P; Murray, R M; McGuffin, P; Collier, D A; Owen, M J; Craddock, N

    1999-10-15

    Evidence consistent with the existence of genetic linkage between bipolar disorder and three regions on chromosome 18, the pericentromeric region, 18q21, and 18q22-q23 have been reported. Some analyses indicated greater evidence for linkage in pedigrees in which paternal transmission of disease occurs. We have undertaken linkage analyses using 12 highly polymorphic markers spanning these three regions of interest in a sample of 48 U.K. bipolar pedigrees. The sample comprises predominantly nuclear families and includes 118 subjects with Diagnostic and Statistical Manual of Mental Disorders (DSM IV) bipolar I disorder and 147 subjects with broadly defined phenotype. Our data do not provide support for linkage using either parametric or nonparametric analyses. Evidence for linkage was not significantly increased by analyses that allowed for heterogeneity nor by analysing the subset of pedigrees consistent with paternal transmission.

  19. The pharmacist Aggregate Demand Index to explain changing pharmacist demand over a ten-year period.

    Science.gov (United States)

    Knapp, Katherine K; Shah, Bijal M; Barnett, Mitchell J

    2010-12-15

    To describe Aggregate Demand Index (ADI) trends from 1999-2010; to compare ADI time trends to concurrent data for US unemployment levels, US entry-level pharmacy graduates, and US retail prescription growth rate; and to determine which variables were significant predictors of ADI. Annual ADI data (dependent variable) were analyzed against annual unemployment rates, annual number of pharmacy graduates, and annual prescription growth rate (independent variables). ADI data trended toward lower demand levels for pharmacists since late 2006, paralleling the US economic downturn. National ADI data were most highly correlated with unemployment (p graduates (p unemployment was a significant ADI predictor. Unemployment and ADI also were significantly related at the regional, division, and state levels. The ADI is strongly linked to US unemployment rates. The relationship suggests that an improving economy might coincide with increased pharmacist demand. Predictable increases in future graduates and other factors support revisiting the modeling process as new data accumulate.

  20. DEMAND FOR BEEF IN THE PROVINCE OF YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Sulistiya

    2014-07-01

    Full Text Available RACT Protein consumption level of society in Yogyakarta Province has yet to meet the target, but the beef is a source of animal protein that is easily obtainable. Therefore, research on the analysis of demand for beef in this province needs to be done. Objective: (1 Determine the factors that affect the demand for beef in Yogyakarta. (2 Determine the own price elasticity and income elasticity of demand for beef in this province, and to know the cross-price elasticity of demand for beef to changes in the price of mutton, chicken, rice, and cooking oil. Metode: descriptive statistics, followed by inductive statistics , and hypothesis testing. The data used are primary and secondary data. Data were analyzed by multiple linear regression with the value of t and F tests, and analysis of the coefficient of determination. Results: Taken together, the factors that affect the demand for beef in the province is the price of beef, mutton, chicken, rice, cooking oil, income, number of inhabitants. Individually, beef demand is influenced by the price of beef and income residents. Beef inelastic demand means that beef is the daily necessities that are affordable and easy to obtain population of Yogyakarta Province. The increase in income population does not add to demand for beef. Substitutes of beef in the province is goat and chicken, while the complementary goods are rice and cooking oil.

  1. Is direct marketing a risk factor? Inaccurate forecasting of power generation from renewables raises the demand for balancing power; Risikofaktor Direktvermarktung? Durch ungenaue Prognosen bei der Einspeisung von gruenem Strom steigt der Bedarf an Regelleistung

    Energy Technology Data Exchange (ETDEWEB)

    Korn, Stefan

    2012-05-15

    Since the amendment of the EEG in January 2012, enormous amounts of electric power from renewable energy sources are marketed directly, i.e. outside the control of power supply grid owners and operators that formerly sold the electric power in the stock exchange. Inaccurate prognoses made by the direct marketers as well as their marketing strategies have increased the demand for balancing power and made critical situations in the power grid even more difficult.

  2. Electricity demand for South Korean residential sector

    Energy Technology Data Exchange (ETDEWEB)

    Sa' ad, Suleiman, E-mail: suleimansaad@gmail.co [Surrey Energy Economics Centre (SEEC), Department of Economics, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom)

    2009-12-15

    This study estimates the electricity demand function for the residential sector of South Korea with the aim of examining the effects of improved energy efficiency, structural factors and household lifestyles on electricity consumption. In the study, time series data for the period from 1973 to 2007 is used in a structural time series model to estimate the long-term price and income elasticities and annual growth of underlying energy demand trend (UEDT) at the end of the estimation period. The result shows a long-term income elasticity of 1.33 and a long-term price elasticity of -0.27% with -0.93% as the percentage growth of UEDT at the end of the estimation period. This result suggests that, in order to encourage energy efficiency in the residential sector, the government should complement the market based pricing policies with non-market policies such as minimum energy efficiency standards and public enlightenment.

  3. Electricity demand for South Korean residential sector

    Energy Technology Data Exchange (ETDEWEB)

    Sa' ad, Suleiman [Surrey Energy Economics Centre (SEEC), Department of Economics, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom)

    2009-12-15

    This study estimates the electricity demand function for the residential sector of South Korea with the aim of examining the effects of improved energy efficiency, structural factors and household lifestyles on electricity consumption. In the study, time series data for the period from 1973 to 2007 is used in a structural time series model to estimate the long-term price and income elasticities and annual growth of underlying energy demand trend (UEDT) at the end of the estimation period. The result shows a long-term income elasticity of 1.33 and a long-term price elasticity of -0.27% with -0.93% as the percentage growth of UEDT at the end of the estimation period. This result suggests that, in order to encourage energy efficiency in the residential sector, the government should complement the market based pricing policies with non-market policies such as minimum energy efficiency standards and public enlightenment. (author)

  4. On-demand treatment in persons with severe haemophilia.

    Science.gov (United States)

    Saulyte Trakymiene, Sonata; Steen Carlsson, Katarina

    2014-08-01

    There are two main modes of replacement therapy for haemophilia patients: either to stop bleeding (on-demand) or regular infusions of clotting factor to prevent bleeds (prophylaxis). Fifty yr of clinical experience have provided evidence of the superiority of prophylaxis by showing a reduction in bleeds and development of arthropathy. Prophylaxis has been described extensively in terms of efficacy and health-economic aspects; however, on-demand treatment has received less attention. The aim of this study was to critically review the published literature on PubMed and discuss potential gaps of knowledge in on-demand treatment in persons with severe haemophilia without inhibitors by focusing on two key aspects: how on-demand treatment is provided and what outcome measures have been reported. We identified 134 papers of which 112 were excluded. Of the remaining 22 papers, 16 were comparative studies between prophylaxis and on-demand treatment and six were descriptions of on-demand treatment. The results showed limited reporting on data related to the key aspects of treatment on-demand. Early studies looked at degrees of joint bleeds and different treatment regimens in finding the optimal dose. However, from the late 1980s, there was almost no research into on-demand therapy except efficacy and safety studies of new rFVIII products and studies to prove superiority of prophylaxis over treatment on-demand. The success of on-demand therapy may depend on several factors, for example time to initial dose after a bleed and duration of treatment. Data on these key factors are limited and highlight the necessity of research to optimise replacement therapy. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. The first-generation Daphnia magna linkage map

    Directory of Open Access Journals (Sweden)

    De Meester Luc

    2010-09-01

    Full Text Available Abstract Background Daphnia magna is a well-established model species in ecotoxicology, ecology and evolution. Several new genomics tools are presently under development for this species; among them, a linkage map is a first requirement for estimating the genetic background of phenotypic traits in quantitative trait loci (QTL studies and is also very useful in assembling the genome. It also enables comparative studies between D. magna and D. pulex, for which a linkage map already exists. Results Here we describe the first genetic linkage map of D. magna. We generated 214 F2 (intercross clonal lines as the foundation of the linkage analysis. The linkage map itself is based on 109 microsatellite markers, which produced ten major linkage groups ranging in size from 31.1 cM to 288.5 cM. The total size of this linkage map extends to 1211.6 Kosambi cM, and the average interval for the markers within linkage groups is 15.1 cM. The F2 clones can be used to map QTLs for traits that differ between the parental clones. We successfully mapped the location of two loci with infertility alleles, one inherited from the paternal clone (Iinb1 and the other from the maternal clone (Xinb3. Conclusions The D. magna linkage map presented here provides extensive coverage of the genome and a given density of markers that enable us to detect QTLs of moderate to strong effects. It is similar in size to the linkage map of D. pulex.

  6. Resource use, dependence and vulnerability: community-resource linkages on Alaska's Tongass National Forest

    Science.gov (United States)

    E.T. Mekbeb; R.J. Lilieholm; D.J. Blahna; L.E. Kruger

    2009-01-01

    Understanding how rural communities use and depend upon local natural resources is a critical factor in developing policies to sustain the long-term viability of human and natural systems. Such “community-resource” linkages are particularly important in Alaska, where rural communities – many of them comprised of indigenous Alaskan Natives – are highly dependent upon...

  7. [MapDraw: a microsoft excel macro for drawing genetic linkage maps based on given genetic linkage data].

    Science.gov (United States)

    Liu, Ren-Hu; Meng, Jin-Ling

    2003-05-01

    MAPMAKER is one of the most widely used computer software package for constructing genetic linkage maps.However, the PC version, MAPMAKER 3.0 for PC, could not draw the genetic linkage maps that its Macintosh version, MAPMAKER 3.0 for Macintosh,was able to do. Especially in recent years, Macintosh computer is much less popular than PC. Most of the geneticists use PC to analyze their genetic linkage data. So a new computer software to draw the same genetic linkage maps on PC as the MAPMAKER for Macintosh to do on Macintosh has been crying for. Microsoft Excel,one component of Microsoft Office package, is one of the most popular software in laboratory data processing. Microsoft Visual Basic for Applications (VBA) is one of the most powerful functions of Microsoft Excel. Using this program language, we can take creative control of Excel, including genetic linkage map construction, automatic data processing and more. In this paper, a Microsoft Excel macro called MapDraw is constructed to draw genetic linkage maps on PC computer based on given genetic linkage data. Use this software,you can freely construct beautiful genetic linkage map in Excel and freely edit and copy it to Word or other application. This software is just an Excel format file. You can freely copy it from ftp://211.69.140.177 or ftp://brassica.hzau.edu.cn and the source code can be found in Excel's Visual Basic Editor.

  8. What Influences Linkage to Care After Home-Based HIV Counseling and Testing?

    Science.gov (United States)

    Naik, Reshma; Zembe, Wanga; Adigun, Fatima; Jackson, Elizabeth; Tabana, Hanani; Jackson, Debra; Feeley, Frank; Doherty, Tanya

    2017-06-22

    To maximize the benefits of test and treat strategies that utilize community-based HIV testing, clients who test positive must link to care in a timely manner. However, linkage rates across the HIV treatment cascade are typically low and little is known about what might facilitate or hinder care-seeking behavior. This qualitative study was conducted within a home-based HIV counseling and testing (HBHCT) intervention in South Africa. In-depth interviews were conducted with 30 HBHCT clients who tested HIV positive to explore what influenced their care-seeking behavior. A set of field notes for 196 additional HBHCT clients who tested HIV positive at home were also reviewed and analyzed. Content analysis showed that linkage to care is influenced by a myriad of factors at the individual, relationship, community, and health system levels. These factors subtly interact and at times reinforce each other. While some factors such as belief in test results, coping ability, social support, and prior experiences with the health system affect clients' desire and motivation to seek care, others such as limited time and resources affect their agency to do so. To ensure that the benefits of community-based testing models are realized through timely linkage to care, programs and interventions must take into account and address clients' emotions, motivation levels, living situations, relationship dynamics, responsibilities, and personal resources.

  9. Energy supply and demand in California

    Science.gov (United States)

    Griffith, E. D.

    1978-01-01

    The author expresses his views on future energy demand on the west coast of the United States and how that energy demand translates into demand for major fuels. He identifies the major uncertainties in determining what future demands may be. The major supply options that are available to meet projected demands and the policy implications that flow from these options are discussed.

  10. Performance of random forest when SNPs are in linkage disequilibrium

    Directory of Open Access Journals (Sweden)

    Cupples L Adrienne

    2009-03-01

    Full Text Available Abstract Background Single nucleotide polymorphisms (SNPs may be correlated due to linkage disequilibrium (LD. Association studies look for both direct and indirect associations with disease loci. In a Random Forest (RF analysis, correlation between a true risk SNP and SNPs in LD may lead to diminished variable importance for the true risk SNP. One approach to address this problem is to select SNPs in linkage equilibrium (LE for analysis. Here, we explore alternative methods for dealing with SNPs in LD: change the tree-building algorithm by building each tree in an RF only with SNPs in LE, modify the importance measure (IM, and use haplotypes instead of SNPs to build a RF. Results We evaluated the performance of our alternative methods by simulation of a spectrum of complex genetics models. When a haplotype rather than an individual SNP is the risk factor, we find that the original Random Forest method performed on SNPs provides good performance. When individual, genotyped SNPs are the risk factors, we find that the stronger the genetic effect, the stronger the effect LD has on the performance of the original RF. A revised importance measure used with the original RF is relatively robust to LD among SNPs; this revised importance measure used with the revised RF is sometimes inflated. Overall, we find that the revised importance measure used with the original RF is the best choice when the genetic model and the number of SNPs in LD with risk SNPs are unknown. For the haplotype-based method, under a multiplicative heterogeneity model, we observed a decrease in the performance of RF with increasing LD among the SNPs in the haplotype. Conclusion Our results suggest that by strategically revising the Random Forest method tree-building or importance measure calculation, power can increase when LD exists between SNPs. We conclude that the revised Random Forest method performed on SNPs offers an advantage of not requiring genotype phase, making it a

  11. International Oil Supplies and Demands

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    The eleventh Energy Modeling Forum (EMF) working group met four times over the 1989--90 period to compare alternative perspectives on international oil supplies and demands through 2010 and to discuss how alternative supply and demand trends influence the world's dependence upon Middle Eastern oil. Proprietors of eleven economic models of the world oil market used their respective models to simulate a dozen scenarios using standardized assumptions. From its inception, the study was not designed to focus on the short-run impacts of disruptions on oil markets. Nor did the working group attempt to provide a forecast or just a single view of the likely future path for oil prices. The model results guided the group's thinking about many important longer-run market relationships and helped to identify differences of opinion about future oil supplies, demands, and dependence.

  12. International Oil Supplies and Demands

    Energy Technology Data Exchange (ETDEWEB)

    1992-04-01

    The eleventh Energy Modeling Forum (EMF) working group met four times over the 1989--1990 period to compare alternative perspectives on international oil supplies and demands through 2010 and to discuss how alternative supply and demand trends influence the world's dependence upon Middle Eastern oil. Proprietors of eleven economic models of the world oil market used their respective models to simulate a dozen scenarios using standardized assumptions. From its inception, the study was not designed to focus on the short-run impacts of disruptions on oil markets. Nor did the working group attempt to provide a forecast or just a single view of the likely future path for oil prices. The model results guided the group's thinking about many important longer-run market relationships and helped to identify differences of opinion about future oil supplies, demands, and dependence.

  13. Fundamental Travel Demand Model Example

    Science.gov (United States)

    Hanssen, Joel

    2010-01-01

    Instances of transportation models are abundant and detailed "how to" instruction is available in the form of transportation software help documentation. The purpose of this paper is to look at the fundamental inputs required to build a transportation model by developing an example passenger travel demand model. The example model reduces the scale to a manageable size for the purpose of illustrating the data collection and analysis required before the first step of the model begins. This aspect of the model development would not reasonably be discussed in software help documentation (it is assumed the model developer comes prepared). Recommendations are derived from the example passenger travel demand model to suggest future work regarding the data collection and analysis required for a freight travel demand model.

  14. ANALYSIS OF INTER SECTORAL LINKAGES IN SEMARANG REGENCY

    Directory of Open Access Journals (Sweden)

    Fafurida

    2014-03-01

    Full Text Available This research aims to analyze inter economic sectoral linkages and to arrange the Klassen typology of economic sectors in Semarang Regency. The Klassen typology is composed from the result of the linkage analysis. To construct the analysis, this paper also utulizes the input-output analysis. It finds that service sector has the highest backward linkage while farming sector has the highest forward linkage. Based on the Klassen typology analysis, sectors with the highest backward and forward linkages and potential to be the leading sector are farming sector, dan trade, hotel and restaurant sector.Keywords: Backward linkage,forward linkage, Klassen typologyJEL classification number: R15, O21AbstrakPenelitian ini bertujuan untuk mengkaji seberapa besar keterkaitan antar sektor ekonomi di Kabupaten Semarang dan memetakan tipologi Klassennya. Tipologi Klasen disusun berdasarkan hasil perhitungan analisis keterkaitannya. Untuk menyusun analisis tersebut, paper ini juga menggunakan analisis input-output. Hasil penelitian menunjukkan bahwa sektor jasa memiliki keterkaitan ke belakang tertinggi dibandingkan dengan sektor lainnya. Sementara itu, sektor pertanian merupakan sektor yang memiliki keterkaitan ke depan tertinggi. Berdasarkan hasil analisis tipologi Klassen, sektor yang memiliki keterkaitan ke depan dan ke belakang yang tinggi dan dapat menjadi sektor unggulan adalah sektor perdagangan, hotel dan sektor restoran.Kata kunci: Keterkaitan ke belakang, keterkaitan ke depan, tipologi KlassenJEL classification numbers: R15, O21

  15. Kinematic and Dynamic Characteristics Analysis of Bennett’ s Linkage

    Institute of Scientific and Technical Information of China (English)

    Jianfeng Li

    2015-01-01

    Bennett’ s linkage is a spatial fourlink linkage, and has an extensive application prospect in the deployable linkages.Its kinematic and dynamic characteristics analysis has a great significance in its synthesis and application. According to the geometrical conditions of Bennett ’ s linkage, the motion equations are established,and the expressions of angular displacement, angular velocity and angular acceleration of the followers and the displacement, velocity and acceleration of mass center of link are shown. Based on Lagrange’ s equation, the multi⁃rigid⁃body dynamic model of Bennett’ s linkage is established. In order to solve the reaction forces and moments of joint, screw theory and reciprocal screw method are combined to establish the computing method.The number of equations and unknown reaction forces and moments of joint are equal through adding link deformation equations. The influence of the included angle of adjacent axes on Bennett ’ s linkage ’ s kinematic characteristics, the dynamic characteristics and the reaction forces and moments of joint are analyzed. Results show that the included angle of adjacent axes has a great effect on velocity, acceleration, the reaction forces and moments of Bennett’ s linkage. The change of reaction forces and moments of joint are apparent near the singularity configuration.

  16. Credit demand in Mozambican manufacturing

    DEFF Research Database (Denmark)

    Byiers, Bruce; Rand, John; Tarp, Finn

    2010-01-01

    manager education and business association membership are associated with whether a firm is credit constrained or not. Using our preferred measure of credit constraint suggests that around 43 per cent of the firms surveyed are constrained, and these enterprises would almost triple their debt burden......This paper uses two industrial firm surveys to identify the key determinants of credit demand in Mozambican manufacturing. We construct five different measures of being credit constrained and estimate desired debt demand. Besides firm size and ownership structure, we find evidence that general...

  17. Demand inducement as cheap talk.

    Science.gov (United States)

    Calcott, P

    1999-12-01

    The doctor-patient interaction is analysed in a game of cheap talk. Causes and consequences of imperfect agency are examined. One form of imperfect agency, supplier-induced demand, is a feature of neologism proof equilibria with some parameter values but not with others. The model is used to evaluate two tests that have been used to test for the existence of supplier-induced demand. The analysis suggests that the two tests, which compare the medical utilization of informed and uninformed consumers, are not valid.

  18. Identifying marker typing incompatibilities in linkage analysis

    Energy Technology Data Exchange (ETDEWEB)

    Stringham, H.M.; Boehnke, M. [Univ. of Michigan, Ann Arbor, MI (United States)

    1996-10-01

    A common problem encountered in linkage analyses is that execution of the computer program is halted because of genotypes in the data that are inconsistent with Mendelian inheritance. Such inconsistencies may arise because of pedigree errors or errors in typing. In some cases, the source of the inconsistencies is easily identified by examining the pedigree. In others, the error is not obvious, and substantial time and effort are required to identify the responsible genotypes. We have developed two methods for automatically identifying those individuals whose genotypes are most likely the cause of the inconsistencies. First, we calculate the posterior probability of genotyping error for each member of the pedigree, given the marker data on all pedigree members and allowing anyone in the pedigree to have an error. Second, we identify those individuals whose genotypes could be solely responsible for the inconsistency in the pedigree. We illustrate these methods with two examples: one a pedigree error, the second a genotyping error. These methods have been implemented as a module of the pedigree analysis program package MENDEL. 9 refs., 2 figs., 2 tabs.

  19. Multipoint linkage detection in the presence of heterogeneity.

    Science.gov (United States)

    Chiu, Yen-Feng; Liang, Kung-Yee; Beaty, Terri H

    2002-06-01

    Linkage heterogeneity is common for complex diseases. It is well known that loss of statistical power for detecting linkage will result if one assumes complete homogeneity in the presence of linkage heterogeneity. To this end, Smith (1963, Annals of Human Genetics 27, 175-182) proposed an admixture model to account for linkage heterogeneity. It is well known that for this model, the conventional chi-squared approximation to the likelihood ratio test for no linkage does not apply even when the sample size is large. By dealing with nuclear families and one marker at a time for genetic diseases with simple modes of inheritance, score-based test statistics (Liang and Rathouz, 1999, Biometrics 55, 65-74) and likelihood-ratio-based test statistics (Lemdani and Pons, 1995, Biometrics 51, 1033-1041) have been proposed which have a simple large-sample distribution under the null hypothesis of linkage. In this paper, we extend their work to more practical situations that include information from multiple markers and multi-generational pedigrees while allowing for a class of general genetic models. Three different approaches are proposed to eliminate the nuisance parameters in these test statistics. We show that all three approaches lead to the same asymptotic distribution under the null hypothesis of no linkage. Simulation results show that the proposed test statistics have adequate power to detect linkage and that the performances of these two classes of test statistics are quite comparable. We have applied the proposed method to a family study of asthma (Barnes et al., 1996), in which the score-based test shows evidence of linkage with p-value <0.0001 in the region of interest on chromosome 12. Additionally, we have implemented this score-based test within the frequently used computer package GENEHUNTER.

  20. 46 CFR 169.689 - Demand loads.

    Science.gov (United States)

    2010-10-01

    ... Electrical Electrical Installations on Vessels of 100 Gross Tons and Over § 169.689 Demand loads. Demand loads must meet § 111.60-7 of this chapter except that smaller demand loads for motor feeders...

  1. Water demand management research: A psychological perspective

    Science.gov (United States)

    Russell, Sally; Fielding, Kelly

    2010-05-01

    The availability of fresh water for human consumption is a critical global issue and one that will be exacerbated by the impacts of climate change. Water demand management has an important role to play in reducing the vulnerability of freshwater supplies to climate change impacts. In this paper, we argue that the field of psychology and environmental psychology in particular can make a vital contribution in understanding further the drivers of residential water demand. A growing body of literature in environmental psychology has examined the determinants of water conservation behavior, and this research has many potential applications for water demand policy. In this paper we offer a review of current psychological research that examines the five broad causes of residential water conservation behaviors: attitudes, beliefs, habits or routines, personal capabilities, and contextual factors. We assess how psychologists have studied water conservation behavior to date, identify shortcomings, and indicate how this research can be used to further promote residential water conservation and to inform evidence-based policy and practice.

  2. Demand for International Reserves in Turkey

    Directory of Open Access Journals (Sweden)

    Yimaz Sinem

    2014-06-01

    Full Text Available Having an important place in the international monetary system, international reserves held by central bank usually reflect country’s economic strength in terms of international finance and trade. There are many reasons for holding international reserves by central banks such as financing the deficit in the balance of payment, managing the monetary and exchange rate policies, minimizing the negative effects of external shocks and reducing the cost of borrowing. Continuously changing and diversifying characteristics of these reasons affect the demand for reserves depending to the economic conditions of the country. Over the last ten years, there has been a tremendous increase in international reserves held by Turkish Central Bank. From 2002 to 2012, the reserves of the bank have risen from 20 billion dollars to 96 billion dollars, showing an increase more than four times. This sudden and huge increase in the foreign reserves drove us to determine and investigate the factors which induce the Turkish Central Bank to hold high level of reserves. Thus, the purpose of this study is to estimate and analyze the demand for international reserves held by central banks using the buffer stock model in the case of Turkey. The data used in the study is monthly and cover the period of 1990:03-2012:10. The buffer stock model was econometrically estimated by using the OLS method for three different models. Our findings indicate that the opportunity cost affected reserve demand much stronger than the reserve volatility in Turkish case.

  3. Farmers’Demands on Forestry Socialized Services and its Influencing Factors---A Survey Based on 1 413 Households in 8 Provinces%农户林业社会化服务需求特征及其影响因素分析*--基于我国8省(区)1413户农户的调查

    Institute of Scientific and Technical Information of China (English)

    廖文梅; 张广来; 孔凡斌

    2016-01-01

    Objective] This paper tried to clear the demand features of farmers in forestry socialized services ( FSS) and its affecting mechanisms of the key factors. The results provided the scientific basis for improving FSS system in China and supporting policy after the reform of collective forestry property.[Method]Taking 1 413 households in 8 Provinces ( districts) of China as samples,farmers’demands of FSS and its influencing factors were analyzed by a Logistic model.[Result]In total,the demands of farmers FSS were urgent at the level of 75. 26%. In regards of the factors affecting farmer demands on FSS,there were 4 incurring factors that significantly affected 6 kinds’demands of FSS. Those factors were whether to join the forestry professional cooperative organization or not,whether to accept service charges or not,whether to suffer the corresponding difficulties or not and whether to supply corresponding services at local place or not.[Conclusion]In all FSS,farmers ’ demands prefer to occur on both production and marketing processes. It could significantly stimulate farmers’demands of FSS by improving the effective supply of FSS. The function role of forest cooperatives in FSS was very limited. Service charges had obviously inhibition effects on farmers’demands of FSS. Based on above conclusions,some policy implications were obtained.%【目的】明确农户林业社会化服务需求特征及其关键影响因素的作用机制,为完善集体林权制度改革后我国林业社会化服务体系及支持政策提供科学依据。【方法】基于我国8省(区)集体林区的1413户农户调查数据,运用 Logistic 模型,实证分析集体林区农户林业社会化服务需求及其影响因素。【结果】75.26%的农户对林业社会化服务需求意愿十分迫切。在影响农户林业社会化服务需求的因素中,农户是否加入林业合作组织、是否接受服务收费、是否经历相应的困境和当地是否提供

  4. Si{endash}N linkage in ultrabright, ultrasmall Si nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Rogozhina, E.; Belomoin, G.; Smith, A.; Abuhassan, L.; Barry, N.; Akcakir, O.; Braun, P. V.; Nayfeh, M. H.

    2001-06-04

    Ultrabright ultrasmall ({similar_to}1 nm) blue luminescent Si{sub 29} nanoparticles are chlorinated by reaction with Cl{sub 2} gas. A Si{endash}N linkage is formed by the reaction of the chlorinated particles with the functional amine group in butylamine. Fourier transform infrared spectroscopy and x-ray photospectroscopy measurements confirm the N linkage and the presence of the butyl group, while emission, excitation, and autocorrelation femtosecond optical spectroscopy show that, after the linkage formation, the particles with the ultrabright blue luminescent remain, but with a redshift of 40 nm. {copyright} 2001 American Institute of Physics.

  5. Recombination patterns reveal information about centromere location on linkage maps

    DEFF Research Database (Denmark)

    Limborg, Morten T.; McKinney, Garrett J.; Seeb, Lisa W.

    2016-01-01

    , approximate centromere placement is possible by phasing the same data used to generate linkage maps. Assuming one obligate crossover per chromosome arm, information about centromere location can be revealed by tracking the accumulated recombination frequency along linkage groups, similar to half....... mykiss) characterized by low and unevenly distributed recombination – a general feature of male meiosis in many species. Further, a high frequency of double crossovers along chromosome arms in barley reduced resolution for locating centromeric regions on most linkage groups. Despite these limitations......, our method should work well for high‐density maps in species with strong recombination interference and will enrich many existing and future mapping resources....

  6. Stochastic model of forecasting spare parts demand

    Directory of Open Access Journals (Sweden)

    Ivan S. Milojević

    2012-01-01

    Full Text Available If demand is known for the whole planning period (complete information, then this type of demand or a supply system is deterministic. In the simplest cases, the demand per time unit is constant. If demand levels change over time following a precisely determined and pre-known principle, this type of demand is also classified as deterministic. This quality of demand is very rare. In most cases demand is the product of a process, for example TMS maintenance, whose progression cannot be predicted due to a number of factors influencing the process and causing random demand changes. In this case, a supply system must function according to the complete information and with a certain degree of uncertainty. In cases when demand may be defined by some of the laws of the probability theory, we are talking about stochastic demand and a stochastic supply system. Demand can be described by mathematical expectation, mathematical expectation and standard deviation, probability distribution or as a random process. However, there is usually a need for the most complex description, i.e. the complex random process because both intensity of demand and the probability distribution change during the observed intervals. The level of temporal (dynamic series is traditionally considered as a complex phenomenon consisting of four components: - basic tendency of phenomenon development - cyclical impact (long-term, 'ancient' - seasonal effects - random fluctuations. The basic tendency of phenomenon development means a long-term evolution of phenomena. A function that expresses the trajectory of changes of the basic tendency of a phenomenon development in the form of the equation is called a trend. Often, the trend involves time regression; i.e. the coefficients of the proposed functions are often determined by the least squares method. To roughly determine the coefficients of the proposed function, the sum of three and three-point methods are also used. After checking the

  7. THE PRICE OF HIGHER EDUCATION AND INDIVIDUAL DEMAND

    Directory of Open Access Journals (Sweden)

    Filiz Golpek

    2012-01-01

    Full Text Available The rise in the living standards in most of the world, the rise in population and schooling rates have increased the demand for higher education. The attribution of semi public property becomes determinant to decide whom will provide the supply and the production in semi public properties is realized by means of a supply and demand mechanism. The supply of higher education is mostly secured in accordance with the public demand as well as the resources available.  In addition, the fact that higher education services have produced significant benefits has led to over demand. This situation relates to a simple economic rule that a commodity or service which costs almost nothing or little will increase until the mariginal benefit of its demand equals to 0 or almost 0. However, the educational supply and demand is difficult to identify in accordance to the supply and demand and balance of price as observed in the economic theory. The high profits that would be attracted in the future are significant factors influencing individual’s decisions for investment. The decision for investment depends on the possible return in the future, the cost of investment, and the current interest rates. Higher education with investment purposes is influenced by these three factors and higher education is demanded more and more by individuals on the expectation that they will gain high profits In theory, it is accepted that the basic factors identifying the demand for higher education are in harmony with empirical research results in several countries including Turkey.

  8. Home Network Technologies and Automating Demand Response

    Energy Technology Data Exchange (ETDEWEB)

    McParland, Charles

    2009-12-01

    Over the past several years, interest in large-scale control of peak energy demand and total consumption has increased. While motivated by a number of factors, this interest has primarily been spurred on the demand side by the increasing cost of energy and, on the supply side by the limited ability of utilities to build sufficient electricity generation capacity to meet unrestrained future demand. To address peak electricity use Demand Response (DR) systems are being proposed to motivate reductions in electricity use through the use of price incentives. DR systems are also be design to shift or curtail energy demand at critical times when the generation, transmission, and distribution systems (i.e. the 'grid') are threatened with instabilities. To be effectively deployed on a large-scale, these proposed DR systems need to be automated. Automation will require robust and efficient data communications infrastructures across geographically dispersed markets. The present availability of widespread Internet connectivity and inexpensive, reliable computing hardware combined with the growing confidence in the capabilities of distributed, application-level communications protocols suggests that now is the time for designing and deploying practical systems. Centralized computer systems that are capable of providing continuous signals to automate customers reduction of power demand, are known as Demand Response Automation Servers (DRAS). The deployment of prototype DRAS systems has already begun - with most initial deployments targeting large commercial and industrial (C & I) customers. An examination of the current overall energy consumption by economic sector shows that the C & I market is responsible for roughly half of all energy consumption in the US. On a per customer basis, large C & I customers clearly have the most to offer - and to gain - by participating in DR programs to reduce peak demand. And, by concentrating on a small number of relatively

  9. Future demand for electricity in the Nassau--Suffolk region

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, T.W.; Palmedo, P.F.; Stern, R.

    1977-12-01

    Brookhaven National Laboratory established a new technology for load forecasting for the Long Island Lighting Company and prepared an independent forecast of the demand for electricity in the LILCO area. The method includes: demand for electricity placed in a total energy perspective so that substitutions between electricity and other fuels can be examined; assessment of the impact of conservation, new technology, gas curtailment, and other factors upon demand for electricity; and construction of the probability distribution of the demand for electricity. A detailed analysis of changing levels of demand for electricity, and other fuels, associated with these new developments is founded upon a disaggregated end-use characterization of energy utilization, including space heat, lighting, process energy, etc., coupled to basic driving forces for future demand, namely: population, housing mix, and economic growth in the region. The range of future events covers conservation, heat pumps, solar systems, storage resistance heaters, electric vehicles, extension of electrified rail, total energy systems, and gas curtailment. Based upon cost and other elements of the competition between technologies, BNL assessed the likelihood of these future developments. An optimistic view toward conservation leads to ''low'' demand for electricity, whereas rapid development of new technologies suggests ''high'' demand. (MCW)

  10. The Logit Test of Influencing Factors of Farmers'Credit Demand and Credit Constraint---Based on the Empirical Analysis of 905 Peasant Households of Shangluo City%农户信贷需求与信贷约束影响因素的Logit检验--基于商洛市905户农户的实证分析

    Institute of Scientific and Technical Information of China (English)

    王红莉

    2014-01-01

    本文依据对商洛市905户农户信贷需求情况的调研数据,运用Logit模型分别对农户信贷需求、农户金融机构信贷需求和农户金融机构信贷约束的影响因素进行实证检验,既从需求视角估计农户借贷需求和金融机构信贷需求的影响因素,又从供给视角估计农户信贷需求得不到满足的制约因素。结果表明,商洛农户的潜在信贷需求强烈,但由于自身收入水平较低、文化程度不高、生活消费性借款不愿承受较高的利息支出等因素,农户不愿意向金融机构借款;与此同时,农户选择向金融机构贷款时,由于没有熟人、缺乏抵押物、没有被评定为信用户等因素制约,较难从金融机构获得贷款满足。最后,本文从扩展农户金融需求、增加农村金融供给两方面提出缓解农户“贷款难”和金融机构“放贷难”的政策建议。%According to the survey data of the situation of the credit demand of 905 peasant households of Shangluo city,using Logit model, the paper makes the empirical test on the influencing factors of farmers' credit demand, farmer financial institutions'credit demand and farmer financial institutions'credit constraint, and not only estimates the influencing factors of farmers'credit de-mand and financial institutions'credit demand from the perspective of demand, but also estimates the influencing factors that farmers'credit demand can't be satisfied from the perspective of supply. The results show that the potential credit demand of farmers in Shangluo city is strong, but due to that the level of their own income is low, their cultural level is not high, they are not willing to bear the high interest rate for consumption loans, and farmers are not willing to borrow money from financial institutions. At the same time, when the peasant households choose to get loans from financial institutions, because they have no acquaintance, lack of collateral, and

  11. Regional Differences in the Demand for Agricultural Socialized Service

    Institute of Scientific and Technical Information of China (English)

    Lu; LI

    2015-01-01

    With the gradual deepening of China’s agricultural modernization,establishing a sound agricultural socialized service system is of great significance to improving the efficiency of resource use and achieving sustainable agricultural development. On the basis of the micro survey data on China’s 12 provinces,we analyze the intensity of demand for agricultural socialized service in different regions as well as the main factors influencing farmers’ demand willingness. The results show that there are regional differences in farmers’ demand for agricultural socialized service,and among multiple factors affecting the demand willingness of agricultural socialized service,farmers’ individual characteristics,household economic characteristics and farmers’ social communication behavior have varying degrees of impact on farmers’ choice of service.

  12. Simulation of annual electric lighting demand using various occupancy profiles

    DEFF Research Database (Denmark)

    Iversen, Anne; Andersen, Philip Hvidthøft Delff; Svendsen, Svend

    2013-01-01

    This paper describes an investigation of the effect on electric lighting demand of applying occupancy models of various resolution to climate-based daylight modelling. The lighting demand was evaluated for a building zone with the occupant always present, with occupancy corresponding to absence...... factors, based on an estimated annual mean occupancy, based on estimated 1-hour mean occupancy, and based on 2-min occupancy intervals. The results showed little difference in the annual electric lighting demand when the same occupancy profile was used every day, as opposed to when profiles were used...... where occupancy varied every day. Furthermore, the results showed that annual electric lighting demand was evaluated slightly conservatively when a mean absence factor was applied as opposed to using dynamic occupancy profiles....

  13. Demand Controlled Ventilation and Classroom Ventilation

    Energy Technology Data Exchange (ETDEWEB)

    Fisk, William J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mendell, Mark J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Davies, Molly [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Eliseeva, Ekaterina [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Faulkner, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hong, Tienzen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sullivan, Douglas P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-05-01

    This document summarizes a research effort on demand controlled ventilation and classroom ventilation. The research on demand controlled ventilation included field studies and building energy modeling.

  14. Demand as frequency-controlled reserve

    Energy Technology Data Exchange (ETDEWEB)

    Bang, C.; Togeby, M.; Holmboe, N.M.; Brus, R. [Ea Energianalyse A/S, Copenhagen (Denmark); Brandt Rasmussen, C.; Oestergaard, J.; Douglas, P.J. [DTU CEE, Kgs. Lyngby (Denmark); Lund Nielsen, K. [Danfoss, Nordborg (Denmark); Gorzelak, L. [Vestfrost, Esbjerg (Denmark); Rolsted Mattesen, M. [Oestkraft, Roenne (Denmark)

    2013-05-15

    The project is based upon active control of electricity demand as function of grid frequency. Data have been collected from domestic households and industrial loads covering i.e. circulation pumps, electrical domestic heating, bottle coolers, a wastewater treatment plant etc. A special electronic device, referred to as the ''SmartBox'', has been developed during the project. The SmartBox has the ability to control a connected load by either on/off (shutting down the mains for the appliance) or by altering the temperature set-point digitally for a thermostat. The box measure all relevant data from the attached demand and sends the data by mobile network to a central server. The SmartBox is configurable from a website where it is possible to i.e.: upload new firmware for the devices, configure of various parameters and access measurement data. The practical demonstration has included data from about: 1) 50 pcs. Carlsberg Vestfrost bottle coolers (control by thermostat). 2) 20 pcs. Danfoss DEVI electrical domestic heating (control by thermostat). 3) 20 pcs. Bornholm Forsyning water purifying plant (control by SCADA). 4) 30 pcs. Various on/off controlling circulation pumps, dehumidifiers, freezers, heaters etc. Electronic Housekeeper, a consumer product was installed in domestic households connected to i.e. freezers, refrigerators and electrical heating. The product included all necessary hardware to control the attached appliance as function of frequency. The product was customized to deliver data for the project as well. Basically all tests has shown, that it is possible the postpone electricity demands as a function of frequency and thereby help maintaining the system balance. The flexibility depends on the size of the actual consumption and its capacity. By the capacity means the interaction of factors as: how fast the demand reacts, the probability that it reacts and the timespan of the possible reaction. (Author)

  15. Transnational linkages and sustainable transitions in emerging countries: Exploring the role of donor interventions in niche development

    DEFF Research Database (Denmark)

    Hansen, Ulrich Elmer; Nygaard, Ivan

    2013-01-01

    Recent studies have found that further development of the MLP is needed to conceptualise and empirically assess the role of transnational linkages in niche development. This paper explores the factors that may explain the effect of twenty years of donor interventions as one form of transnational...... linkage in promoting the development of a palm oil biomass waste-to-energy niche in Malaysia. The paper contributes to the existing literature by a conceptual and empirical examination of this research question. With regard to its empirical findings the paper concludes: (i) that advice on energy policy...

  16. Voltage Controlled Dynamic Demand Response

    DEFF Research Database (Denmark)

    Bhattarai, Bishnu Prasad; Bak-Jensen, Birgitte; Mahat, Pukar

    2013-01-01

    . An adaptive dynamic model has been developed to determine composite voltage dependency of an aggregated load on feeder level. Following the demand dispatch or control signal, optimum voltage setting at the LV substation is determined based on the voltage dependency of the load. Furthermore, a new technique...

  17. The moral demands of affluence

    DEFF Research Database (Denmark)

    Sønderholm, Jørn

    2015-01-01

    In 2004, Garrett Cullity made a significant contribution to the literature on what the world’s relatively affluent owe to the world’s relatively poor through the publishing of The Moral Demands of Affluence. In this discussion note, I draw attention to a logical problem in Cullity’s master argument...

  18. Projecting Electricity Demand in 2050

    Energy Technology Data Exchange (ETDEWEB)

    Hostick, Donna J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Belzer, David B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hadley, Stanton W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Markel, Tony [National Renewable Energy Lab. (NREL), Golden, CO (United States); Marnay, Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Kintner-Meyer, Michael C. W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-07-01

    This paper describes the development of end-use electricity projections and load curves that were developed for the Renewable Electricity (RE) Futures Study (hereafter RE Futures), which explored the prospect of higher percentages (30% - 90%) of total electricity generation that could be supplied by renewable sources in the United States. As input to RE Futures, two projections of electricity demand were produced representing reasonable upper and lower bounds of electricity demand out to 2050. The electric sector models used in RE Futures required underlying load profiles, so RE Futures also produced load profile data in two formats: 8760 hourly data for the year 2050 for the GridView model, and in 2-year increments for 17 time slices as input to the Regional Energy Deployment System (ReEDS) model. The process for developing demand projections and load profiles involved three steps: discussion regarding the scenario approach and general assumptions, literature reviews to determine readily available data, and development of the demand curves and load profiles.

  19. Demand-Side Energy Management

    NARCIS (Netherlands)

    Molderink, Albert; Iniewski, K.

    2012-01-01

    Concerns about climate change, increasing energy prices and dependability of energy supply ask for drastic changes in the energy supply chain, but also in the current demand-supply philosophy. Current trends in energy consumptions result in an increasing and more fluctuating electricity usage, causi

  20. Physical Demands Study - Focus Groups

    Science.gov (United States)

    2015-10-26

    and the rounds in the boxes weigh 35 lb, which is lighter than equipment handled in the other physically demanding job tasks already identified...and standards. Ergonomics . 53: 858-871. 40 Appendix A: Questionnaires Completed by Volunteers prior to each Focus Group Interview 1 2 3 4a 4b 5

  1. The Cognitive Demands of Writing

    NARCIS (Netherlands)

    Torrance, Mark; Jeffery, Gaynor

    1999-01-01

    Writing is a complex activity that places demands on cognitive resources. This volume presents original theory and research exploring the ways in which the sub-components of the writing process (generating and organizing content, producing grammatical sentences, etc.) differ in their cognitive deman

  2. Market demands to Danish pork

    DEFF Research Database (Denmark)

    Bredahl, Lone

    2001-01-01

    . The study focuses on the development on the most important markets for Danish pork. The countries are Denmark, Japan, UK, Germany, Italy, France, USA, Russia and South Korea. The primary purpose is to identify market demands of importance to the Danish pork sector in order to maintain and strengthen its...

  3. Cotton Demand Dropping in China

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The ICAC claimed, global cotton market outlook is bleak in the 2012/2013 annual. Global cotton production is estimated at 25.9 million tons and cotton usage is estimated at 23.4 million tons. Cotton supply will exceed demand; the excess volume will reach 2.4 million tons.

  4. Demand as Frequency Controlled Reserve

    DEFF Research Database (Denmark)

    Xu, Zhao; Østergaard, Jacob; Togeby, Mikael

    2011-01-01

    Relying on generation side alone is deemed insufficient to fulfill the system balancing needs for future Danish power system, where a 50% wind penetration is outlined by the government for year 2025. This paper investigates using the electricity demand as frequency controlled reserve (DFR) as a new...

  5. Employer Demands from Business Graduates

    Science.gov (United States)

    McMurray, Stephen; Dutton, Matthew; McQuaid, Ronald; Richard, Alec

    2016-01-01

    Purpose: The purpose of this paper is to report on research carried out with employers to determine demand for business and management skills in the Scottish workforce. Design/methodology/approach: The research used a questionnaire in which employers were interviewed (either telephone or face to face), completed themselves and returned by e-mail,…

  6. Linkage analysis of genes for resistance to downy mildew (Bremia lactucae) in lettuce (Lactuca sativa).

    Science.gov (United States)

    Hulbert, S H; Michelmore, R W

    1985-08-01

    The genetics of specific resistance was studied in F2 populations which segregated for either one or two resistance genes. The resistance factors 1, 11 and 14 which had not previously been characterized genetically segregated as single dominant genes (Dm). Resistance was determined by three linkage groups; R 1/14, 2, 3, and 6 in the first, R 5/8, and 10 in the second and R 4, 7 and 11 in the third. Cultivars of lettuce commonly used in the differential series to detect virulence to R3 and R10, were demonstrated to carry two tightly linked resistance genes. Implications of this linkage arrangement to the manipulation and characterization of these resistance genes are discussed.

  7. Occurrence and linkage between secreted insecticidal toxins in natural isolates of Bacillus thuringiensis.

    Science.gov (United States)

    Espinasse, Sylvain; Chaufaux, Josette; Buisson, Christophe; Perchat, Stéphane; Gohar, Michel; Bourguet, Denis; Sanchis, Vincent

    2003-12-01

    Little is known about the occurrence and linkage between secreted insecticidal virulence factors in natural populations of Bacillus thuringiensis (Bt). We carried out a survey of 392 Bt strains isolated from various samples originating from 31 countries. The toxicity profile of the culture supernatants of these strains was determined individually against Anthonomus grandis (Coleoptera) and Spodoptera littoralis (Lepidoptera). We analyzed beta-exotoxin I production and searched for the genes encoding Vip1-2, Vip3, and Cry1I toxins in 125 of these strains. Our results showed that these insecticidal toxins were widespread in Bt but that their distribution was nonrandom, with significant linkage observed between vip3 and cry1I and between vip1-2 and beta-exotoxin I. Strains producing significant amounts of beta-exotoxin I were more frequently isolated from invertebrate samples than from dust, water, soil, or plant samples.

  8. A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits.

    Directory of Open Access Journals (Sweden)

    Youling Guo

    Full Text Available Hypertension is caused by the interaction of environmental and genetic factors. The condition which is very common, with about 18% of the adult Hong Kong Chinese population and over 50% of older individuals affected, is responsible for considerable morbidity and mortality. To identify genes influencing hypertension and blood pressure, we conducted a combined linkage and association study using over 500,000 single nucleotide polymorphisms (SNPs genotyped in 328 individuals comprising 111 hypertensive probands and their siblings. Using a family-based association test, we found an association with SNPs on chromosome 5q31.1 (rs6596140; P<9 × 10(-8 for hypertension. One candidate gene, PDC, was replicated, with rs3817586 on 1q31.1 attaining P = 2.5 × 10(-4 and 2.9 × 10(-5 in the within-family tests for DBP and MAP, respectively. We also identified regions of significant linkage for systolic and diastolic blood pressure on chromosomes 2q22 and 5p13, respectively. Further family-based association analysis of the linkage peak on chromosome 5 yielded a significant association (rs1605685, P<7 × 10(-5 for DBP. This is the first combined linkage and association study of hypertension and its related quantitative traits with Chinese ancestry. The associations reported here account for the action of common variants whereas the discovery of linkage regions may point to novel targets for rare variant screening.

  9. Demand as frequency controlled reserve

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Z.; Togeby, M.; OEstergaard, J.

    2008-09-15

    Using demand as frequency controlled reserve (DFR) is an emerging technology which allow demand to participate actively in maintaining the system operation without reducing the energy service delivered to the customer and without need of user interaction. The basic premise is that traditional frequency controlled reserves from power plants and interconnections with neighbouring systems can be costly, slow and not fulfil the need for future power grids with a high share of wind power and fewer central power plants, and an intention to perform flexible operation such as is landing. Electricity demands, on the other hand, have advantages as frequency reserve including fast activation speed, smooth linear activation, low expected costs, and well-dispersed in the distribution grid. The main challenge of DFR is new methods for monitoring the available capacity. This project has investigated the technology of using electricity demands for providing frequency reserve to power systems. Within the project the potential and economy of DFR compatible loads in Denmark has been investigated, control logic has been designed, power system impact has been investigated, potential business models has been evaluated and an implementation strategy has been suggested. The tasks and goals of the project have been successfully accomplished based on which the conclusion and future recommendation are made. This project has developed the DFR technology that enables electricity demands to autonomously disconnect or reconnect to the grid in response to system frequency variations. The developed DFR technology is proved to be a promising technology from several perspectives. Technically, using DFR is feasible to provide reserves and enhance power system frequency control, while fulfilling technical requirements such as linear activation (or reconnection) according to frequency (or time). Environmentally, the DFR technology is pollution free in contrast to traditional reserves from generation

  10. A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits.

    Science.gov (United States)

    Guo, Youling; Tomlinson, Brian; Chu, Tanya; Fang, Yu Jing; Gui, Hongsheng; Tang, Clara S; Yip, Benjamin H; Cherny, Stacey S; Hur, Yoon-Mi; Sham, Pak Chung; Lam, Tai Hing; Thomas, Neil G

    2012-01-01

    Hypertension is caused by the interaction of environmental and genetic factors. The condition which is very common, with about 18% of the adult Hong Kong Chinese population and over 50% of older individuals affected, is responsible for considerable morbidity and mortality. To identify genes influencing hypertension and blood pressure, we conducted a combined linkage and association study using over 500,000 single nucleotide polymorphisms (SNPs) genotyped in 328 individuals comprising 111 hypertensive probands and their siblings. Using a family-based association test, we found an association with SNPs on chromosome 5q31.1 (rs6596140; Ppressure on chromosomes 2q22 and 5p13, respectively. Further family-based association analysis of the linkage peak on chromosome 5 yielded a significant association (rs1605685, Prelated quantitative traits with Chinese ancestry. The associations reported here account for the action of common variants whereas the discovery of linkage regions may point to novel targets for rare variant screening.

  11. 咸宁市社区居家老年人精神慰藉需求及其影响因素分析%Analysis of emotional comfort demand of the elderly at home in community in Xianning city and its influencing fac-tors

    Institute of Scientific and Technical Information of China (English)

    孔令磷; 张志霞; 叶艳胜; 汪娟; 马香香; 李秀; 朱晚香

    2016-01-01

    Objective:To probe into emotional comfort demand of the elderly at home in community in Xianning city and its influencing factors.Methods:A total of 476 elderly at home in 4 communities in Xianning city were randomly selected for the questionnaire.Results:The total score for emotional comfort demand was(9.25±3.09);the top two demands were neighborhood mutual assistance(2.61±0.95)and volunteers companying(1.96±1.05);the lowest demand was remarriage(1.14±0.54).Multiple linear regression analysis showed that education lev-el,marital status,self rated health status,living condition and depression status were the maj or factors affect-ing the emotional comfort demand of the elderly,which explained 1 1 .7% of the total variance.Conclusion:Ori-ented by the demands of the elderly,further emotional comfort services should be provided in multi level and multi faceted in order to realize the healthy aging.%[目的]探讨咸宁市社区居家老年人精神慰藉需求现状及影响因素。[方法]随机抽取咸宁市4个社区,对476名老人进行问卷调查。[结果]社区老年人精神慰藉需求总分为(9.25±3.09)分,需求程度前两位为邻里互助(2.61分±0.95分)和志愿者陪伴(1.96分±1.05分),需求程度最低的是老年人婚姻牵线搭桥(1.14分±0.54分);多元线性回归分析显示文化程度、婚姻状况、自评健康状况、居住状况以及抑郁状况是社区居家老年人精神慰藉需求的主要影响因素,共同解释总变异的11.7%。[结论]应以老年人需求为导向,多层次、多方面发展居家养老精神慰藉服务,促进健康老龄化的实现。

  12. Shrubs and Runoff in Semiarid Landscapes: Whats the Linkage?

    Science.gov (United States)

    Wilcox, B. P.; Owens, M. K.; Knight, R.; Lyons, R. K.

    2001-12-01

    Here we examine linkage between streamflow and shrub cover in semiarid landscapes with a focus on the extensive Texas rangelands covered by mesquite and juniper. The conclusions drawn are consistent with results from field studies and with our understanding of runoff processes from rangelands. Whether and how shrub control will affect streamflow depends on shrub characteristics, precipitation, soils, and geology. Precipitation is perhaps the most fundamental of these factors: there is little if any real potential for increasing streamflow where annual precipitation is below about 500 mm. For areas in which precipitation is sufficient, an excellent indicator that there is potential for increasing streamflow through shrub control is that base flow is an important component of streamflow. Another key indicator is shallow soils underlain by fractured parent material; under such conditions, increased streamflows are possible mainly because water that would otherwise be lost through interception by the canopy instead moves into the soil and quickly travels beyond the root zone. Conversely, where soils are deep there is little evidence that streamflow can be significantly increased by reducing brush cover. Results from a 10 year small watershed study where juniper was selectively removed in the Edwards plateau region of Texas will be summarized in this presentation. In assessing the potential for shrub control to increase streamflow, the runoff generation process should be explicitly identified. Areas in which Horton overland flow is the primary runoff mechanism offer little potential for increasing streamflow via vegetation management.

  13. Potential Linkage Between Cerebrovascular Diseases and Metabolic Syndrome.

    Science.gov (United States)

    Jabir, Nasimudeen R; Firoz, Chelapram Kandy; Khan, Mohd Shahnawaz; Zaidi, Syed Kashif; Ashraf, Ghulam Md; Shakil, Shazi; Kamal, Mohammad Amjad; Tabrez, Shams

    2017-01-01

    Cerebrovascular disease (CD) and metabolic syndrome (MetS) are two devastating health dilemma that continues to be a potential contributor to disability and mortality in human population all across the world. Scientific data clearly shows several mechanistic similarities between these two co-existing and interlinked conditions. The linkage exacerbates ongoing patho-physiological condition towards more lethal events. In view of the presence of modifiable risk factors in both CD and MetS, their management holds potential therapeutic value. Hence, developing common treatment strategies for these diseases could involve common molecular agents. In this communication, we have summarized some of the common pathological conditions viz. abdominal obesity, insulin resistance, dyslipidemia, hypertension, and endothelial dysfunction that further deteriorate existing homeostasis in CD and MetS. Based on our article, it is advocated that substantial improvements in novel multi-targeted drug discovery could provide the effective treatment methods in order to avoid the fatal complications related with CD and MetS. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  14. The Mixed Preschool Market: Explaining Local Variation in Family Demand and Organized Supply.

    Science.gov (United States)

    Edwards, John H. Y.; And Others

    1996-01-01

    Explores supply-and-demand factors by combining a 100-county sample of independent preschools with 1990 census data. Price negatively affects hours demanded. More hours are purchased in poorer counties with more black single parents and rapid population growth. Center accreditation significantly increases demand, but depresses supply. Public…

  15. Path analytic, sib-pair linkage and co-twin control studies of asthma and atopy

    Energy Technology Data Exchange (ETDEWEB)

    Duffy, D.L.; Healey, S.C.; Martin, N.G. [Queensland Institute of Medical Research, Brisband (Austria)

    1994-09-01

    Asthma and atopy are complex traits with multifactorial determinants, and require appropriate choice of phenotypes and analyses, including a linkage analysis of the putative 11q atopy locus. Participants in a large registry-based twin study of asthma were invited to take part in clinical testing. A total of 863 individuals including 419 complete twin pairs (where one or both members reported a history of wheeze) underwent histamine inhalation challenge, allergen skin prick testing, and venesection. Total serum immunoglobulin E (IgE) and bronchial responsiveness (BR) to histamine were highest in those who had wheezed most recently, and whose skin tests demonstrated allergy to house dust mite, cockroach, and rye grass. In ascertainment-corrected path analyses (FISHER), the heritability of IgE and BR were both 60%. Monozygotic (MZ) co-twin control analyses suggested house dust mite sensitization was the single strongest environmentally controlled risk factor for wheeze, while path analyses suggested genetic determination. In dizygotic (DZ) co-twin control analyses, sensitization to grasses was also an important predictor, suggesting pollinosis to be genetically correlated with wheezing, rather than causative. Multivariate path analyses suggested separate (correlated) genetic factors for BR, IgE, and allergy to house dust mite. A sib-pair (Haseman-Elston) linkage analysis of 220 DZ twin pairs did not support linkage to the high-affinity IgE receptor beta-subunit gene on 11q13 of atopy or BR. More recent linkage analyses that include parental genotyping will also be discussed. We conclude that the atopic phenotype consists of a number of traits with specific genetic allergens. Exposure to particular allergens can then cause specific outcomes, such as asthma.

  16. Localizing genes using linkage disequilibrium in plants: integrating ...

    African Journals Online (AJOL)

    GREGO

    2007-03-19

    Mar 19, 2007 ... in humans in the presence of population structure. For outbred species, the ..... plants are immotile, distant gene dispersal is largely uniparental (through .... Linkage disequilibrium among modern sugarcane cultivars. Theor.

  17. Predicting sales performance: Strengthening the personality – job performance linkage

    NARCIS (Netherlands)

    T.B. Sitser (Thomas)

    2014-01-01

    markdownabstract__Abstract__ Many organizations worldwide use personality measures to select applicants for sales jobs or to assess incumbent sales employees. In the present dissertation, consisting of four independent studies, five approaches to strengthen the personality-sales performance linkage

  18. Addressing Energy Demand through Demand Response. International Experiences and Practices

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Bo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ghatikar, Girish [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ni, Chun Chun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dudley, Junqiao [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Martin, Phil [Enernoc, Inc., Boston, MA (United States); Wikler, Greg

    2012-06-01

    Demand response (DR) is a load management tool which provides a cost-effective alternative to traditional supply-side solutions to address the growing demand during times of peak electrical load. According to the US Department of Energy (DOE), demand response reflects “changes in electric usage by end-use customers from their normal consumption patterns in response to changes in the price of electricity over time, or to incentive payments designed to induce lower electricity use at times of high wholesale market prices or when system reliability is jeopardized.” 1 The California Energy Commission (CEC) defines DR as “a reduction in customers’ electricity consumption over a given time interval relative to what would otherwise occur in response to a price signal, other financial incentives, or a reliability signal.” 2 This latter definition is perhaps most reflective of how DR is understood and implemented today in countries such as the US, Canada, and Australia where DR is primarily a dispatchable resource responding to signals from utilities, grid operators, and/or load aggregators (or DR providers).

  19. Mapping multiple QTL using linkage disequilibrium and linkage analysis information and multitrait data

    Directory of Open Access Journals (Sweden)

    Goddard Mike E

    2004-05-01

    Full Text Available Abstract A multi-locus QTL mapping method is presented, which combines linkage and linkage disequilibrium (LD information and uses multitrait data. The method assumed a putative QTL at the midpoint of each marker bracket. Whether the putative QTL had an effect or not was sampled using Markov chain Monte Carlo (MCMC methods. The method was tested in dairy cattle data on chromosome 14 where the DGAT1 gene was known to be segregating. The DGAT1 gene was mapped to a region of 0.04 cM, and the effects of the gene were accurately estimated. The fitting of multiple QTL gave a much sharper indication of the QTL position than a single QTL model using multitrait data, probably because the multi-locus QTL mapping reduced the carry over effect of the large DGAT1 gene to adjacent putative QTL positions. This suggests that the method could detect secondary QTL that would, in single point analyses, remain hidden under the broad peak of the dominant QTL. However, no indications for a second QTL affecting dairy traits were found on chromosome 14.

  20. 森林资源产权市场制约因素及对策分析——基于供求视角%Analysis on Forest Resource Property Market's Restriction Factors and Countermeasures: From the Perspective of Supply and Demand

    Institute of Scientific and Technical Information of China (English)

    乔永平; 聂影

    2012-01-01

    目前森林资源产权市场仍处于起步阶段,存在着众多制约市场供求双方的因素.制约需求的因素包括森林资源产权制度不完善、森林资源风险防范机制不健全、林业融资难、林业比较利益低;制约供给的因素包括政策法规不完善、信息不完备、交易成本高、非农就业机会少、社会保障制度不健全等;通过市场中介间接影响供求的因素包括市场中介组织缺乏等.本研究给出了强化森林资源产权市场机制的对策建议.%Current forest resource property market is still at the initial stage and there are many restricting factors that affect both the supply and the demand. The factors restricting the demand are forest resource property systems being imperfect, forest resource risk prevention mechanism being incomplete, forestry financing being difficult, forestry comparative rate of profit being low and so on; the factors restricting the supply include concerning law and policies being imperfect, information being incomplete, trading cost being high, non-agricultural job chance being low, social security system being imperfect and so on; to make it worse, imperfect intermediary organization turns out to be one of the restricting factors affect both the supply and the demand. This research offers some countermeasure suggestions of strengthening forest resource property market mechanism.

  1. International Environmental Problems, Issue Linkage and the European Union

    OpenAIRE

    Kroeze-Gil, J.

    2003-01-01

    This thesis explores the circumstances under which issue linkage can be applied to achieve cooperation on international environmental problems in general and on environmental problems in the European Union in particular. A major topic in this thesis is the development and analysis of cooperative and non-cooperative game theoretical methods of issue linkage that include imperfectly reversed interests. The relevance of the models is shown in the context of EU environmental decision making.

  2. Demand chain management - The evolution

    Directory of Open Access Journals (Sweden)

    D Ericsson

    2011-06-01

    Full Text Available The concepts of Supply Chain Management (SCM and Demand Chain Management (DCM are among the new and debated topics concerning logistics in the literature. The question considered in this paper is: “Are these concepts needed or will they just add to the confusion?” Lasting business concepts have always evolved in close interaction between business and academia. Different approaches start out in business and they are then, more or less si- multaneously, aligned, integrated, systemised and structured in academia. In this way a terminology (or language is provided that helps in further diffusion of the concepts. There is a lack of consensus on the definition of the concept of SCM. This may be one of the major reasons for the difficulty in advancing the science and measuring the results of implementation in business. Relationships in SCM span from rather loose coalitions to highly structured virtual network integrations. DCM is a highly organised chain in which the key is mutual interdependence and partnership. The purpose is to create a distinctive competence for the chain as a whole that helps to identify and satisfy customer needs and wishes. The classical research concerning vertical marketing systems is very helpful in systemising the rather unstructured discussions in current SCM research. The trend lies in increasing competition between channels rather than between companies, which in turn leads to the creation of channels with a high degree of partnership and mutual interdependence between members. These types of channels are known as organised vertical marketing systems in the classic marketing channel research. The behaviour in these types of channels, as well as the formal and informal structures, roles in the network, power and dependence relations, etc. are well covered topics in the literature. The concept of vertical marketing systems lies behind the definition of demand chains and demand chain management proposed in this paper. A

  3. Male homosexuality: absence of linkage to microsatellite markers at Xq28.

    Science.gov (United States)

    Rice, G; Anderson, C; Risch, N; Ebers, G

    1999-04-23

    Several lines of evidence have implicated genetic factors in homosexuality. The most compelling observation has been the report of genetic linkage of male homosexuality to microsatellite markers on the X chromosome. This observation warranted further study and confirmation. Sharing of alleles at position Xq28 was studied in 52 gay male sibling pairs from Canadian families. Four markers at Xq28 were analyzed (DXS1113, BGN, Factor 8, and DXS1108). Allele and haplotype sharing for these markers was not increased over expectation. These results do not support an X-linked gene underlying male homosexuality.

  4. Strong linkages between DOM optical properties and main clades of aquatic bacteria

    DEFF Research Database (Denmark)

    Amaral, Valentina; Graeber, Daniel; Calliari, Danilo

    2016-01-01

    Despite considerable research on the linkages between dissolved organic matter (DOM) and bacteria, it is not yet clear how the abundance of the main aquatic clades relates to DOM composition in natural aquatic systems. We evaluated this relation using PARAFAC modeling of excitation...... factors for modeling their abundance in situ. The combination and significance of the factors was specific for each bacterial group, strongly indicating that they behave as coherent and distinctive units. Cytophaga-Flavobacteria and Betaproteobacteria were the groups which correlated with more DOM...

  5. A high-density screen for linkage in multiple sclerosis.

    Science.gov (United States)

    Sawcer, Stephen; Ban, Maria; Maranian, Mel; Yeo, Tai Wai; Compston, Alastair; Kirby, Andrew; Daly, Mark J; De Jager, Philip L; Walsh, Emily; Lander, Eric S; Rioux, John D; Hafler, David A; Ivinson, Adrian; Rimmler, Jacqueline; Gregory, Simon G; Schmidt, Silke; Pericak-Vance, Margaret A; Akesson, Eva; Hillert, Jan; Datta, Pameli; Oturai, Annette; Ryder, Lars P; Harbo, Hanne F; Spurkland, Anne; Myhr, Kjell-Morten; Laaksonen, Mikko; Booth, David; Heard, Robert; Stewart, Graeme; Lincoln, Robin; Barcellos, Lisa F; Hauser, Stephen L; Oksenberg, Jorge R; Kenealy, Shannon J; Haines, Jonathan L

    2005-09-01

    To provide a definitive linkage map for multiple sclerosis, we have genotyped the Illumina BeadArray linkage mapping panel (version 4) in a data set of 730 multiplex families of Northern European descent. After the application of stringent quality thresholds, data from 4,506 markers in 2,692 individuals were included in the analysis. Multipoint nonparametric linkage analysis revealed highly significant linkage in the major histocompatibility complex (MHC) on chromosome 6p21 (maximum LOD score [MLS] 11.66) and suggestive linkage on chromosomes 17q23 (MLS 2.45) and 5q33 (MLS 2.18). This set of markers achieved a mean information extraction of 79.3% across the genome, with a Mendelian inconsistency rate of only 0.002%. Stratification based on carriage of the multiple sclerosis-associated DRB1*1501 allele failed to identify any other region of linkage with genomewide significance. However, ordered-subset analysis suggested that there may be an additional locus on chromosome 19p13 that acts independent of the main MHC locus. These data illustrate the substantial increase in power that can be achieved with use of the latest tools emerging from the Human Genome Project and indicate that future attempts to systematically identify susceptibility genes for multiple sclerosis will have to involve large sample sizes and an association-based methodology.

  6. Identification of quantitative trait loci underlying milk traits in Spanish dairy sheep using linkage plus combined linkage disequilibrium and linkage analysis approaches.

    Science.gov (United States)

    Garcia-Gámez, E; Gutiérrez-Gil, B; Suarez-Vega, A; de la Fuente, L F; Arranz, J J

    2013-09-01

    In this study, 2 procedures were used to analyze a data set from a whole-genome scan, one based on linkage analysis information and the other combing linkage disequilibrium and linkage analysis (LDLA), to determine the quantitative trait loci (QTL) influencing milk production traits in sheep. A total of 1,696 animals from 16 half-sib families were genotyped using the OvineSNP50 BeadChip (Illumina Inc., San Diego, CA) and analysis was performed using a daughter design. Moreover, the same data set has been previously investigated through a genome-wide association (GWA) analysis and a comparison of results from the 3 methods has been possible. The linkage analysis and LDLA methodologies yielded different results, although some significantly associated regions were common to both procedures. The linkage analysis detected 3 overlapping genome-wise significant QTL on sheep chromosome (OAR) 2 influencing milk yield, protein yield, and fat yield, whereas 34 genome-wise significant QTL regions were detected using the LDLA approach. The most significant QTL for protein and fat percentages was detected on OAR3, which was reported in a previous GWA analysis. Both the linkage analysis and LDLA identified many other chromosome-wise significant associations across different sheep autosomes. Additional analyses were performed on OAR2 and OAR3 to determine the possible causality of the most significant polymorphisms identified for these genetic effects by the previously reported GWA analysis. For OAR3, the analyses demonstrated additional genetic proof of the causality previously suggested by our group for a single nucleotide polymorphism located in the α-lactalbumin gene (LALBA). In summary, although the results shown here suggest that in commercial dairy populations, the LDLA method exhibits a higher efficiency to map QTL than the simple linkage analysis or linkage disequilibrium methods, we believe that comparing the 3 analysis methods is the best approach to obtain a global

  7. Does good leadership buffer effects of high emotional demands at work on risk of antidepressant treatment?

    DEFF Research Database (Denmark)

    Madsen, Ida E H; Hanson, Linda L Magnusson; Rugulies, Reiner Ernst;

    2014-01-01

    Emotionally demanding work has been associated with increased risk of common mental disorders. Because emotional demands may not be preventable in certain occupations, the identification of workplace factors that can modify this association is vital. This article examines whether effects of emoti......Emotionally demanding work has been associated with increased risk of common mental disorders. Because emotional demands may not be preventable in certain occupations, the identification of workplace factors that can modify this association is vital. This article examines whether effects...... of emotional demands on antidepressant treatment, as an indicator of common mental disorders, are buffered by good leadership....

  8. DataBase on demand

    CERN Document Server

    Aparicio, Ruben Gaspar; Coterillo Coz, I

    2012-01-01

    At CERN a number of key database applications are running on user-managed MySQL database services. The database on demand project was born out of an idea to provide the CERN user community with an environment to develop and run database services outside of the actual centralised Oracle based database services. The Database on Demand (DBoD) empowers the user to perform certain actions that had been traditionally done by database administrators, DBA's, providing an enterprise platform for database applications. It also allows the CERN user community to run different database engines, e.g. presently open community version of MySQL and single instance Oracle database server. This article describes a technology approach to face this challenge, a service level agreement, the SLA that the project provides, and an evolution of possible scenarios.

  9. DataBase on Demand

    Science.gov (United States)

    Gaspar Aparicio, R.; Gomez, D.; Coterillo Coz, I.; Wojcik, D.

    2012-12-01

    At CERN a number of key database applications are running on user-managed MySQL database services. The database on demand project was born out of an idea to provide the CERN user community with an environment to develop and run database services outside of the actual centralised Oracle based database services. The Database on Demand (DBoD) empowers the user to perform certain actions that had been traditionally done by database administrators, DBA's, providing an enterprise platform for database applications. It also allows the CERN user community to run different database engines, e.g. presently open community version of MySQL and single instance Oracle database server. This article describes a technology approach to face this challenge, a service level agreement, the SLA that the project provides, and an evolution of possible scenarios.

  10. Energy demand modeling for Uzbekistan

    Directory of Open Access Journals (Sweden)

    Bobur Khodjaev

    2012-05-01

    Full Text Available The paper is devoted to energy demand forecasting in Uzbekistan. Studies show that in spite of the abundant reserves of hydrocarbons, low energy efficiency can have an adverse impact on energy security in Uzbekistan in the future. Oil and gas are the main primary energy source and they ensure energy security of Uzbekistan. Energy demand forecasting is essential in order to develop an effective energy policy. Such forecast can be useful to plan oil and gas production volumes, to identify priorities for the industrial modernization and to create favorable conditions for sustainable economic development in the future. Author proposes model based on translog function for developing medium-and long-term development programs in energy sector and the modernization and technological re-equipment of industry.

  11. Dynamic energy-demand models. A comparison

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Feng [Department of Economics, Goeteborg University, Gothenburg (Sweden)

    2000-04-01

    This paper compares two second-generation dynamic energy demand models, a translog (TL) and a general Leontief (GL), in the study of price elasticities and factor substitutions of nine Swedish manufacturing industries: food, textiles, wood, paper, printing, chemicals, non-metallic minerals, base metals and machinery. Several model specifications are tested with likelihood ratio test. There is a disagreement on short-run adjustments; the TL model accepts putty-putty production technology of immediate adjustments, implying equal short- and long-run price elasticities of factors, while the GL model rejects immediate adjustments, giving out short-run elasticities quite different from the long-run. The two models also disagree in substitutability in many cases. 21 refs.

  12. Disruptive innovation: the demand side.

    Science.gov (United States)

    Havighurst, Clark C

    2008-01-01

    The notion of disruptive innovation provides a welcome framework for considering the prospects for low-cost alternatives in American medicine. Such innovations as have been seen, however, are largely the result of demand by patients paying their own bills because they have high-deductible coverage or are uninsured. Many other cost-saving innovations are discouraged by financing systems that are themselves largely immune to competition from disruptive innovators.

  13. Demand controlled ventilation; Behovsstyrt ventilasjon

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, Henning Holm

    2006-07-01

    The terms CAV and VAV have been known terms for many years in the ventilation business. The terms are also included in building regulations, but the time is now right to focus on demand controlled ventilation (DCV). The new building regulations and the accompanying energy framework underline the need for a more nuanced thinking when it comes to controlling ventilation systems. Descriptions and further details of the ventilation systems are provided (ml)

  14. Fish demand and supply projections

    OpenAIRE

    Sverdrup-Jensen, S.

    1997-01-01

    It has been predicted that the global demand for fish for human consumption will increase by more than 50% over the next 15 years. The FAO has projected that the increase in supply will originate primarily from marine fisheries, aquaculture and to a lesser extent from inland fisheries, but with a commensurate price increase. However, there are constraints to increased production in both marine and inland fisheries, such as overfishing, overexploitation limited potential increase and environme...

  15. Investigating Comparative Advantages of Advance Demand Information in Presence of Heterogeneous Demand

    DEFF Research Database (Denmark)

    Du, Bisheng; Larsen, Christian

    The paper studies aspects of advance demand information and heterogeneous demand in a mathematical model of an inventory system. The concept advance demand information is that customers ahead in time of actual demand place their orders. The concept heterogeneous demand refers to that there are di......The paper studies aspects of advance demand information and heterogeneous demand in a mathematical model of an inventory system. The concept advance demand information is that customers ahead in time of actual demand place their orders. The concept heterogeneous demand refers...

  16. Can TasP Approaches Be Implemented in Correctional Settings?: A review of HIV testing and linkage to community HIV treatment programs.

    Science.gov (United States)

    Elkington, Katherine S; Jaiswal, Jessica; Spector, Anya Y; Reukauf, Heidi; Tesoriero, James M; Nash, Denis; Remien, Robert H

    2016-01-01

    High rates of HIV in correctional populations makes evaluation of programs that increase HIV testing in correctional settings and linkage to HIV treatment upon release, and understanding key implementation issues of these programs, essential to reducing new HIV infection. We conducted a systematic search for studies of outcomes or implementation issues of programs that promote HIV testing or that promote linkage to community HIV treatment post-release. Thirty-five articles met inclusion criteria: nine HIV testing initiatives and four linkage programs. HIV testing uptake rates were between 22% and 98% and rates of linkage to community treatment were between 79% and 84%. Findings suggest that some programs may be effective at reducing HIV transmission within the communities to which inmates return. However, attention to implementation factors, such as organizational culture and staff collaborations, appears critical to the success of these programs. Future research using rigorous design and adequate comparison groups is needed.

  17. Study on Customer Demands for Product Innovation

    Institute of Scientific and Technical Information of China (English)

    XIONG Zhiyong; YANG Mingzhong; LI Yibing; LI Jun

    2006-01-01

    In order to improve the satisfaction degree of customers' individual demands for products and reduce the risk of the product innovation, the characteristics of customer demands for product innovation are analyzed, and the type and content of customer demands are discussed. Then the framework of customer demands acquisition for product innovation is established. Finally, the prototype system of customer demands information acquisition and product customization for product innovation which takes mobile phone as the example is developed successfully.

  18. Empirical of Rural Research on Influence Factors of Credit Demand Households in China Based on Logistic Mode%中国农户信贷需求及其影响因素分析——基于Logistic模型的实证研究

    Institute of Scientific and Technical Information of China (English)

    秦建群; 吕忠伟; 秦建国

    2011-01-01

    本文基于来自中国12个省(市)3051户农户家庭的实地调查数据,运用Logistic模型实证研究了农户信贷需求及其影响因素。研究结果表明,样本农户的年龄与信贷需求之间成倒“u”型关系;农户家庭生命周期、受教育程度会在一定程度上影响信贷需求;农户的家庭收入、家庭规模、家庭负担率以及是否购买养老保险对农户的信贷需求有显著的正向影响。另外,农户从事的经济活动类型也会对农户的信贷需求产生影响,以兼业农户为参照,纯农业农户对信贷需求有显著的正向影响,而非农业农户对信贷需求有显著的负向影响。%Rural households are not only the principal part of agriculture, but also the main demanders of rural financial market. The interpretation of the characteristics, behaviors and living environments of rural households in China is the foundation of the discussion on rural financial problems. This paper studies the credit demands and behaviors of rural households based on survey data from 3051 rural households in 12 prov- inces, municipalities or autonomous regions and investigates the factors affecting the credit demands of rural households with Logistic model. We conclude that age and credit demand of farmers show a reversed "U" pat- tern, that the life cycle and education of farmer family can more or less affect the credit demand of farmer, and that the income, size and labor force burden rate of farmer family and endowment insurance adoption have sig- nificantly positive impact on the credit demand of farmers.

  19. Impacts of Demand-Side Resources on Electric Transmission Planning

    Energy Technology Data Exchange (ETDEWEB)

    Hadley, Stanton W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sanstad, Alan H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-01-01

    Will demand resources such as energy efficiency (EE), demand response (DR), and distributed generation (DG) have an impact on electricity transmission requirements? Five drivers for transmission expansion are discussed: interconnection, reliability, economics, replacement, and policy. With that background, we review the results of a set of transmission studies that were conducted between 2010 and 2013 by electricity regulators, industry representatives, and other stakeholders in the three physical interconnections within the United States. These broad-based studies were funded by the US Department of Energy and included scenarios of reduced load growth due to EE, DR, and DG. While the studies were independent and used different modeling tools and interconnect-specific assumptions, all provided valuable results and insights. However, some caveats exist. Demand resources were evaluated in conjunction with other factors, and limitations on transmission additions between scenarios made understanding the role of demand resources difficult. One study, the western study, included analyses over both 10- and 20-year planning horizons; the 10-year analysis did not show near-term reductions in transmission, but the 20-year indicated fewer transmission additions, yielding a 36percent capital cost reduction. In the eastern study the reductions in demand largely led to reductions in local generation capacity and an increased opportunity for low-cost and renewable generation to export to other regions. The Texas study evaluated generation changes due to demand, and is in the process of examining demand resource impacts on transmission.

  20. The California Linkages Program: Doorway to Housing Support for Child Welfare-Involved Parents.

    Science.gov (United States)

    D'Andrade, Amy; Simon, James David; Fabella, Danna; Castillo, Lolita; Mejia, Cesar; Shuster, David

    2016-11-03

    Housing instability can complicate parents' efforts to provide for their children. Child welfare service agencies have had difficulty adequately serving parents' housing needs due to limited and constrained funding streams. This article integrates the voices of four important stakeholders to illuminate how an innovative model of service system coordination called Linkages addresses housing needs for child welfare-involved parents eligible for public assistance. Facilitated by Linkages, these parents can receive supportive housing services through programs affiliated with the California public assistance program CalWORKs. Personal narratives reflecting the diverse perspectives of stakeholders in the Linkages collaboration-the statewide program director, a child welfare services coordinator, a CalWORKs caseworker, and a parent program participant-shed light on how the collaboration assists parents in attaining case plan goals, and highlights some of the factors facilitating and hindering effective collaboration between the agencies involved. Stakeholders emphasized the value of flexible service approaches, the intensity of the efforts required, the role of advocacy, and the importance of a shared vision between agencies working together to provide housing supports.

  1. Linkage mapping of the human CSF2 and IL3 genes

    Energy Technology Data Exchange (ETDEWEB)

    Frolova, E.I.; Dolganov, G.M.; Mazo, I.A.; Smirnov, D.V. (M.M. Shemyakin Inst. of Bio-organic Chemistry, Moscow (USSR)); Copeland, P.; Stewart, C.; Dean, M. (Program Resources, Inc./DynCorp., Research Triangle Park, NC (United States)); O' Brien, S.J. (National Cancer Inst., Frederick, MD (United States))

    1991-06-01

    Interleukin 3 (encoded by the IL3 gene) and granulocyte-macrophage colony-stimulating factor (encoded by the CSF2 gene) are small secreted polypeptides that bind to specific cell surface receptors and regulate the growth, gene expression, and differentiation of many of the hematopoietic cell lineages, particularly nonlymphoid cells. The IL3 and CSF2 genes have been cloned and mapped to human chromosome bands 5q23-31. Only 10 kilobases of dna separates the two genes, suggesting that they have a common origin and/or regulation. The authors have cloned 70 kilobases of genomic DNA that includes the IL3 and CSF2 genes, as well as flanking sequences, and report a physical map of this region. Several unique-sequence DNA segments have been identified in this region, and one of these fragments detects two restriction fragment length polymorphisms in DNA from unrelated Caucasians. Segregation of these DNA polymorphisms was followed in the Centre Etude du Polymorphisme Humaine (CEPH) panel of 40 large three-generation pedigrees, and linkage was detected with 17 genetic markers previously typed in these families. Multipoint linkage analysis permits the placement of the region containing the IL3 and CSF2 structural genes on the recombination-genetic linkage map of chromosome 5q and thereby allows the role of these genes in leukemogenesis to be more critically examined.

  2. Genome-wide linkage analysis of malaria infection intensity and mild disease.

    Directory of Open Access Journals (Sweden)

    Christian Timmann

    2007-03-01

    Full Text Available Although balancing selection with the sickle-cell trait and other red blood cell disorders has emphasized the interaction between malaria and human genetics, no systematic approach has so far been undertaken towards a comprehensive search for human genome variants influencing malaria. By screening 2,551 families in rural Ghana, West Africa, 108 nuclear families were identified who were exposed to hyperendemic malaria transmission and were homozygous wild-type for the established malaria resistance factors of hemoglobin (HbS, HbC, alpha(+ thalassemia, and glucose-6-phosphate-dehydrogenase deficiency. Of these families, 392 siblings aged 0.5-11 y were characterized for malaria susceptibility by closely monitoring parasite counts, malaria fever episodes, and anemia over 8 mo. An autosome-wide linkage analysis based on 10,000 single-nucleotide polymorphisms was conducted in 68 selected families including 241 siblings forming 330 sib pairs. Several regions were identified which showed evidence for linkage to the parasitological and clinical phenotypes studied, among them a prominent signal on Chromosome 10p15 obtained with malaria fever episodes (asymptotic z score = 4.37, empirical p-value = 4.0 x 10(-5, locus-specific heritability of 37.7%; 95% confidence interval, 15.7%-59.7%. The identification of genetic variants underlying the linkage signals may reveal as yet unrecognized pathways influencing human resistance to malaria.

  3. Survey of perceived stress and work demands of consultant doctors.

    Science.gov (United States)

    Agius, R M; Blenkin, H; Deary, I J; Zealley, H E; Wood, R A

    1996-01-01

    OBJECTIVES: The objectives of this study were to assess the work demands as potential stressors of health service consultants, and to describe the development of tools for measuring stress experiences of consultants. METHODS: A stratified random sample of 500 NHS consultants in Scotland was targeted by a postal questionnaire and 375 (75%) returned a valid response. They completed questionnaires, including information on demographic factors, work demands, occupational stressors, and burnout. RESULTS: Principal components analysis showed that professional work demands of consultants fell into three categories: clinical, academic, and administrative. Their perceived stressors separated into four main factors: clinical responsibility, demands on time, organisational constraints, and personal confidence. These were assessed by 25 questions in the specialist doctors' stress inventory. Specific questions about perceived stressors which resulted in a high positive response included questions about demands on time, and organisational change in the NHS. CONCLUSION: These self reported data characterise and measure the consultants' work demands and their role as potential stressors. These measurements could form the basis for strategies to reduce occupational stress in these workers. PMID:8664957

  4. Demand for abortion and post abortion care in Ibadan, Nigeria.

    Science.gov (United States)

    Awoyemi, Bosede O; Novignon, Jacob

    2014-01-01

    While induced abortion is considered to be illegal and socially unacceptable in Nigeria, it is still practiced by many women in the country. Poor family planning and unsafe abortion practices have daunting effects on maternal health. For instance, Nigeria is on the verge of not meeting the Millennium development goals on maternal health due to high maternal mortality ratio, estimated to be about 630 maternal deaths per 100,000 live births. Recent evidences have shown that a major factor in this trend is the high incidence of abortion in the country. The objective of this paper is, therefore, to investigate the factors determining the demand for abortion and post-abortion care in Ibadan city of Nigeria. The study employed data from a hospital-based/exploratory survey carried out between March to September 2010. Closed ended questionnaires were administered to a sample of 384 women of reproductive age from three hospitals within the Ibadan metropolis in South West Nigeria. However, only 308 valid responses were received and analysed. A probit model was fitted to determine the socioeconomic factors that influence demand for abortion and post-abortion care. The results showed that 62% of respondents demanded for abortion while 52.3% of those that demanded for abortion received post-abortion care. The findings again showed that income was a significant determinant of abortion and post-abortion care demand. Women with higher income were more likely to demand abortion and post-abortion care. Married women were found to be less likely to demand for abortion and post-abortion care. Older women were significantly less likely to demand for abortion and post-abortion care. Mothers' education was only statistically significant in determining abortion demand but not post-abortion care demand. The findings suggest that while abortion is illegal in Nigeria, some women in the Ibadan city do abort unwanted pregnancies. The consequence of this in the absence of proper post

  5. Demand for abortion and post abortion care in Ibadan, Nigeria

    Science.gov (United States)

    2014-01-01

    Background While induced abortion is considered to be illegal and socially unacceptable in Nigeria, it is still practiced by many women in the country. Poor family planning and unsafe abortion practices have daunting effects on maternal health. For instance, Nigeria is on the verge of not meeting the Millennium development goals on maternal health due to high maternal mortality ratio, estimated to be about 630 maternal deaths per 100,000 live births. Recent evidences have shown that a major factor in this trend is the high incidence of abortion in the country. The objective of this paper is, therefore, to investigate the factors determining the demand for abortion and post-abortion care in Ibadan city of Nigeria. Methods The study employed data from a hospital-based/exploratory survey carried out between March to September 2010. Closed ended questionnaires were administered to a sample of 384 women of reproductive age from three hospitals within the Ibadan metropolis in South West Nigeria. However, only 308 valid responses were received and analysed. A probit model was fitted to determine the socioeconomic factors that influence demand for abortion and post-abortion care. Results The results showed that 62% of respondents demanded for abortion while 52.3% of those that demanded for abortion received post-abortion care. The findings again showed that income was a significant determinant of abortion and post-abortion care demand. Women with higher income were more likely to demand abortion and post-abortion care. Married women were found to be less likely to demand for abortion and post-abortion care. Older women were significantly less likely to demand for abortion and post-abortion care. Mothers’ education was only statistically significant in determining abortion demand but not post-abortion care demand. Conclusion The findings suggest that while abortion is illegal in Nigeria, some women in the Ibadan city do abort unwanted pregnancies. The consequence of this

  6. Use of land facets to design linkages for climate change.

    Science.gov (United States)

    Brost, Brian M; Beier, Paul

    2012-01-01

    Least-cost modeling for focal species is the most widely used method for designing conservation corridors and linkages. However, these linkages have been based on current species' distributions and land cover, both of which will change with large-scale climate change. One method to develop corridors that facilitate species' shifting distributions is to incorporate climate models into their design. But this approach is enormously complex and prone to error propagation. It also produces outputs at a grain size (km2) coarser than the grain at which conservation decisions are made. One way to avoid these problems is to design linkages for the continuity and interspersion of land facets, or recurring landscape units of relatively uniform topography and soils. This coarse-filter approach aims to conserve the arenas of biological activity rather than the temporary occupants of those arenas. In this paper, we demonstrate how land facets can be defined in a rule-based and adaptable way, and how they can be used for linkage design in the face of climate change. We used fuzzy c-means cluster analysis to define land facets with respect to four topographic variables (elevation, slope angle, solar insolation, and topographic position), and least-cost analysis to design linkages that include one corridor per land facet. To demonstrate the flexibility of our procedures, we designed linkages using land facets in three topographically diverse landscapes in Arizona, USA. Our procedures can use other variables, including soil variables, to define land facets. We advocate using land facets to complement, rather than replace, existing focal species approaches to linkage design. This approach can be used even in regions lacking land cover maps and is not affected by the bias and patchiness common in species occurrence data.

  7. RLT-S: A Web System for Record Linkage.

    Directory of Open Access Journals (Sweden)

    Abdullah-Al Mamun

    Full Text Available Record linkage integrates records across multiple related data sources identifying duplicates and accounting for possible errors. Real life applications require efficient algorithms to merge these voluminous data sources to find out all records belonging to same individuals. Our recently devised highly efficient record linkage algorithms provide best-known solutions to this challenging problem.We have developed RLT-S, a freely available web tool, which implements our single linkage clustering algorithm for record linkage. This tool requires input data sets and a small set of configuration settings about these files to work efficiently. RLT-S employs exact match clustering, blocking on a specified attribute and single linkage based hierarchical clustering among these blocks.RLT-S is an implementation package of our sequential record linkage algorithm. It outperforms previous best-known implementations by a large margin. The tool is at least two times faster for any dataset than the previous best-known tools.RLT-S tool implements our record linkage algorithm that outperforms previous best-known algorithms in this area. This website also contains necessary information such as instructions, submission history, feedback, publications and some other sections to facilitate the usage of the tool.RLT-S is integrated into http://www.rlatools.com, which is currently serving this tool only. The tool is freely available and can be used without login. All data files used in this paper have been stored in https://github.com/abdullah009/DataRLATools. For copies of the relevant programs please see https://github.com/abdullah009/RLATools.

  8. Demand chain management – The implementation

    Directory of Open Access Journals (Sweden)

    D Ericsson

    2011-12-01

    Full Text Available Most current supply chain models were developed during a period of relative stability. Today, the environment is discontinuous, volatile and unpredictable. This requires a major rethinking and revitalisation of existing supply chain models. Supply chains are much more than warehouses, transportation and technology, they are people powered and have to be treated as social and political as well as economic and technical systems.The most difficult yet challenging and rewarding factor is the change of mindset from approaches based on the old industrial paradigm to the new knowledge oriented paradigm. From "one size fits all" to customisation and buyer behaviour oriented segmentation based on structural flexibility. The new approach requires a change of processes and management systems, but most of all, a change of mindset, organisation structure and behaviour.This may create internal resistance that has to be overcome to reach the desired future state. This future state is highly dependent on cooperation and consensus with external companies, and the next step is therefore to extend the alignment approach to the chosen partners in the demand chain. The development towards channel rather than company competition requires an interorganisational approach to channel design. Internal alignment and cooperation is necessary but not sufficient, which means that an agile and dynamically aligned demand chain has to be created.All this is well known and documented in both research and theory. However, the challenge is to implement these theories, models and behaviour in practice. This paper presents one practical approach to implementation of the theories put forth by Ericsson [Ericsson D, 2011, Demand chain management - The evolution, ORiON, 27(1, pp. 45-81.].

  9. Social obstacles in curbing residential energy demand

    Energy Technology Data Exchange (ETDEWEB)

    Anker-Nilssen, Per [Norwegian School of Management BI, Sandvika (Norway). Centre for Energy and Environment

    2003-07-01

    The continuing growth in residential energy-use does not comply with policy targets for curbing end-user demand. Households are steadily increasing their energy-use, offsetting energy efficiency improvements, to gain time, convenience, comfort and mobility. If sustainable development presupposes lowering demand, it conflicts with present energy-driven changes in life-styles. Environmental degradation due to energy-use gives incentives to raise taxes and duties. The Norwegian experience is that rising income increase households' energy consumption while decreasing its share of total expense. Consequently, higher prices hit low-income households that account for a minor share of total household demand. Since energy represents a purchased input factor to accomplish tasks, the burden is twofold. Energy consumption losses also represent the loss of time and thus money. Additionally, these households have less financial reserves to invest in energy saving. Hence, impact of price hikes (e.g. cold weather) has a regressive social effect. This paper argues that heavy taxation of end-user energy within current practices including tax recycling or deduction, is neither advisable nor politically viable to obtain set targets. Panel data of individual households' electricity use in Oslo suggests that low-income households can not counteract sudden price-hikes but adjust long-term, while the opposite applies to high-income households. In the discussion on environmental policy towards energy-use, the socio-economic effect of measures must be emphasised. New conceptualisations of the world-wide problems in energy and mobility that transforms into agreements on e.g. emission control, can result in added burdens on the poor in industrialised countries rather than the developing countries at large.

  10. A demand chain design for Chinese oatmeal companies

    Directory of Open Access Journals (Sweden)

    Haitao Wen

    2015-04-01

    Full Text Available Purpose: The purpose of this paper is to provide a demand chain design framework for Chinese small and medium enterprises in the oatmeal industry, to help them blaze a new trail in China's oatmeal market. Design/methodology/approach: The approach using in the demand chain design is extended Quality Function Development (QFD, which provides a communication tool so that designers can find a way to integrate customers’ needs into design chain. Findings: This paper illustrates an investigation of oatmeal consumed in China, and the result shows 9 factors influencing consumer’s purchasing decisions mostly. Then use these factors to design the demand chain, and the most important processes and tasks for the enterprises are come out from the fist and the second House of Quality (HOQ, which are the main part of the design. Finally, a demand chain design is completed. Research limitations/implications: It is an application of a demand chain design framework in real Chinese oatmeal market, but the data sample is limited. Consumption surveys should have more data sources with more detailed consumer groups. And the design model needs more real-life examples to verify Practical implications: Since oatmeal products industry develops rapidly in China, oatmeal market is becoming a vast bright market. And due to the low customer satisfaction of Chinese oatmeal market, it is crucial that companies can find a way to design their demand chain, so they can completely meet the needs. Originality/value: A demand chain design framework is presented with being specific to Chinese oatmeal market. It shows a real-life example of demand chain design, and provides the domestic oatmeal companies with an approach to compete in the market.

  11. Physical demands during folk dancing.

    Science.gov (United States)

    Wigaeus, E; Kilbom, A

    1980-01-01

    This investigation was undertaken to evaluate the aerobic demands during one of the most popular and demanding Swedish folk dances the "hambo". Six men and six women, ranging in age from 22 to 32, participated. Their physical work capacity was investigated on a bicycle ergometer and a treadmill, using two to three submaximal and one maximal loads. All subjects were moderately well-trained and their average maximal oxygen uptake on the treadmill were 2.5 and 3.7 l/min (42.8 and 53.2 ml/kg . min-1) for women and men, respectively. When dancing the "hambo" the heart rate was telemetered, and the Douglas bag technique was used for measurements of pulmonary ventilation and oxygen uptake. The physical demand during "hambo" dancing was high in all subjects. Oxygen uptake was 38.5 and 37.3 ml/kg . min-1 and heart rate 179 and 172 in women and men, respectively. Women used 90% and men 70% of their maximal aerobic power obtained on the treadmill. The pulmonary ventilation and respiratory quotient of the female subjects were lower when dancing as compared to running, possibly because of voluntary restriction of the movements of the thoracic cage. Some popular Scandinavian folk dances are performed at a speed and with an activity pattern resembling the "hambo", while others are performed at a slower pace. The exercise intensity used in "hambo" is more than sufficient to induce training effects in the average individual provided that the dancing is performed at the frequency and for length of time usually recommended for physical training. For older or less fit people dances with a slow pace can be used for training purposes.

  12. Duck (Anas platyrhynchos) linkage mapping by AFLP fingerprinting.

    Science.gov (United States)

    Huang, Chang-Wen; Cheng, Yu-Shin; Rouvier, Roger; Yang, Kuo-Tai; Wu, Chean-Ping; Huang, Hsiu-Lin; Huang, Mu-Chiou

    2009-03-17

    Amplified fragment length polymorphism (AFLP) with multicolored fluorescent molecular markers was used to analyze duck (Anas platyrhynchos) genomic DNA and to construct the first AFLP genetic linkage map. These markers were developed and genotyped in 766 F2 individuals from six families from a cross between two different selected duck lines, brown Tsaiya and Pekin. Two hundred and ninety-six polymorphic bands (64% of all bands) were detected using 18 pairs of fluorescent TaqI/EcoRI primer combinations. Each primer set produced a range of 7 to 29 fragments in the reactions, and generated on average 16.4 polymorphic bands. The AFLP linkage map included 260 co-dominant markers distributed in 32 linkage groups. Twenty-one co-dominant markers were not linked with any other marker. Each linkage group contained three to 63 molecular markers and their size ranged between 19.0 cM and 171.9 cM. This AFLP linkage map provides important information for establishing a duck chromosome map, for mapping quantitative trait loci (QTL mapping) and for breeding applications.

  13. Duck (Anas platyrhynchos linkage mapping by AFLP fingerprinting

    Directory of Open Access Journals (Sweden)

    Yang Kuo-Tai

    2009-03-01

    Full Text Available Abstract Amplified fragment length polymorphism (AFLP with multicolored fluorescent molecular markers was used to analyze duck (Anas platyrhynchos genomic DNA and to construct the first AFLP genetic linkage map. These markers were developed and genotyped in 766 F2 individuals from six families from a cross between two different selected duck lines, brown Tsaiya and Pekin. Two hundred and ninety-six polymorphic bands (64% of all bands were detected using 18 pairs of fluorescent TaqI/EcoRI primer combinations. Each primer set produced a range of 7 to 29 fragments in the reactions, and generated on average 16.4 polymorphic bands. The AFLP linkage map included 260 co-dominant markers distributed in 32 linkage groups. Twenty-one co-dominant markers were not linked with any other marker. Each linkage group contained three to 63 molecular markers and their size ranged between 19.0 cM and 171.9 cM. This AFLP linkage map provides important information for establishing a duck chromosome map, for mapping quantitative trait loci (QTL mapping and for breeding applications.

  14. The first genetic linkage map of Eucommia ulmoides

    Indian Academy of Sciences (India)

    Dawei Wang; Yu Li; Long Li; Yongcheng Wei; Zhouqi Li

    2014-04-01

    In accordance with pseudo-testcross strategy, the first genetic linkage map of Eucommia ulmoides Oliv. was constructed by an F1 population of 122 plants using amplified fragment length polymorphism (AFLP) markers. A total of 22 AFLP primer combinations generated 363 polymorphic markers. We selected 289 markers segregating as 1:1 and used them for constructing the parent-specific linkage maps. Among the candidate markers, 127 markers were placed on the maternal map LF and 108 markers on the paternal map Q1. The maternal map LF spanned 1116.1 cM in 14 linkage groups with a mean map distance of 8.78 cM; the paternal map Q1 spanned 929.6 cM in 12 linkage groups with an average spacing of 8.61 cM. The estimated coverage of the genome through two methods was 78.5 and 73.9% for LF, and 76.8 and 71.2% for Q1, respectively. This map is the first linkage map of E. ulmoides and provides a basis for mapping quantitative-trait loci and breeding applications.

  15. Emotional labor demands and compensating wage differentials.

    Science.gov (United States)

    Glomb, Theresa M; Kammeyer-Mueller, John D; Rotundo, Maria

    2004-08-01

    The concept of emotional labor demands and their effects on workers has received considerable attention in recent years, with most studies concentrating on stress, burnout, satisfaction, or other affective outcomes. This study extends the literature by examining the relationship between emotional labor demands and wages at the occupational level. Theories describing the expected effects of job demands and working conditions on wages are described. Results suggest that higher levels of emotional labor demands are associated with lower wage rates for jobs low in cognitive demands and with higher wage rates for jobs high in cognitive demands. Implications of these findings are discussed. (c) 2004 APA

  16. Economic Rebalancing and Electricity Demand in China

    Energy Technology Data Exchange (ETDEWEB)

    He, Gang [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Advanced Light Source (ALS); Stony Brook Univ., NY (United States); Lin, Jiang [Energy Foundation, Beijing (China); Yuan, Alexandria [Energy Foundation, Beijing (China)

    2015-11-01

    Understanding the relationship between economic growth and electricity use is essential for power systems planning. This need is particularly acute now in China, as the Chinese economy is going through a transition to a more consumption and service oriented economy. This study uses 20 years of provincial data on gross domestic product (GDP) and electricity consumption to examine the relationship between these two factors. We observe a plateauing effect of electricity consumption in the richest provinces, as the electricity demand saturates and the economy develops and moves to a more service-based economy. There is a wide range of forecasts for electricity use in 2030, ranging from 5,308 to 8,292 kWh per capita, using different estimating functions, as well as in existing studies. It is therefore critical to examine more carefully the relationship between electricity use and economic development, as China transitions to a new growth phase that is likely to be less energy and resource intensive. The results of this study suggest that policymakers and power system planners in China should seriously re-evaluate power demand projections and the need for new generation capacity to avoid over-investment that could lead to stranded generation assets.

  17. An Empirical Research on the Factors of Unemplyment Insurance Satisfying Job Losers' Demands -An inverstigation of Tiangong street%失业保险金满足失业者需求影响因素的实证研究—基于对南京市朝天宫街道的调查

    Institute of Scientific and Technical Information of China (English)

    黄阳涛; 周蕾

    2012-01-01

    The empirical research on the factors of unemployment insurance satisfying job losers' demands is done by using the Logistic model, based on the statistics from Chao Tiangong Subdistrict in Nanjing. The research has suggested that the more working experiences and money, the better the job losers' demands will be satisfied; The factors of gender and time for getting the money will have negative correlations with the ablity of meeting demands. Therefore, suggestions are given that the labor security apartment should encourage job losers to actively hunt for jobs or carve out, and the level of the unemployment insurance should be adjusted in time.%以南京市朝天宫街道11个社区失业居民的访谈数据为基础,使用Logistic模型,对影响失业保险金满足失业者需求的因素进行了实证研究。研究表明,工作经历越多、领取金额越高,失业者的需求越能得到满足;性别、领取时间对失业保险金的满足能力产生负向的影响。基于此,提出劳动保障部门应鼓励失业者积极寻找工作或创业、失业保险金应作及时调整的政策建议。

  18. Demand Response Valuation Frameworks Paper

    Energy Technology Data Exchange (ETDEWEB)

    Heffner, Grayson

    2009-02-01

    While there is general agreement that demand response (DR) is a valued component in a utility resource plan, there is a lack of consensus regarding how to value DR. Establishing the value of DR is a prerequisite to determining how much and what types of DR should be implemented, to which customers DR should be targeted, and a key determinant that drives the development of economically viable DR consumer technology. Most approaches for quantifying the value of DR focus on changes in utility system revenue requirements based on resource plans with and without DR. This ''utility centric'' approach does not assign any value to DR impacts that lower energy and capacity prices, improve reliability, lower system and network operating costs, produce better air quality, and provide improved customer choice and control. Proper valuation of these benefits requires a different basis for monetization. The review concludes that no single methodology today adequately captures the wide range of benefits and value potentially attributed to DR. To provide a more comprehensive valuation approach, current methods such as the Standard Practice Method (SPM) will most likely have to be supplemented with one or more alternative benefit-valuation approaches. This report provides an updated perspective on the DR valuation framework. It includes an introduction and four chapters that address the key elements of demand response valuation, a comprehensive literature review, and specific research recommendations.

  19. Living with the extreme demand

    Directory of Open Access Journals (Sweden)

    Teppo Eskelinen

    2013-05-01

    Full Text Available Most of the ethical literature on extreme poverty suggests, that some, if not most, of the incomes of the residents of rich countries ought to be donated to the global poor. Yet complying with this ethical demand becomes increasingly more difficult as the changes in lifestyle in the (postindustrial north demand ever more consumption in order to obtain the necessities for survival in such societies. In this article, I will discuss Peter Singer's famous arguments for the ethical duty to donate one's possessions, and elaborate the conception of needs prevalent in both Singer's theory and the theories of many of his critics. My argument is that we have to recognise a category of needs called 'social necessities' that are neither luxuries nor basic needs. This leads to two main conclusions: first, the space for ethical deliberation on whether to donate to life-saving purposes is socially conditioned; and second, ethical strategies of redistribution ought to be accompanied with institutional changes, which also concern the conditions in wealthy countries.http://dx.doi.org/10.5324/eip.v7i1.1791

  20. Demand Side Bidding. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Spahn, Andrew

    2003-12-31

    This document sets forth the final report for a financial assistance award for the National Association of Regulatory Utility Commissioners (NARUC) to enhance coordination between the building operators and power system operators in terms of demand-side responses to Location Based Marginal Pricing (LBMP). Potential benefits of this project include improved power system reliability, enhanced environmental quality, mitigation of high locational prices within congested areas, and the reduction of market barriers for demand-side market participants. NARUC, led by its Committee on Energy Resources and the Environment (ERE), actively works to promote the development and use of energy efficiency and clean distributive energy policies within the framework of a dynamic regulatory environment. Electric industry restructuring, energy shortages in California, and energy market transformation intensifies the need for reliable information and strategies regarding electric reliability policy and practice. NARUC promotes clean distributive generation and increased energy efficiency in the context of the energy sector restructuring process. NARUC, through ERE's Subcommittee on Energy Efficiency, strives to improve energy efficiency by creating working markets. Market transformation seeks opportunities where small amounts of investment can create sustainable markets for more efficient products, services, and design practices.

  1. Positional demands of professional rugby.

    Science.gov (United States)

    Lindsay, Angus; Draper, Nick; Lewis, John; Gieseg, Steven P; Gill, Nicholas

    2015-01-01

    Rugby union is a physically intense intermittent sport coupled with high force collisions. Each position within a team has specific requirements which are typically based on speed, size and skill. The aim of this study was to investigate the contemporary demands of each position and whether they can explain changes in psychophysiological stress. Urine and saliva samples were collected before and after five selected Super 15 rugby games from 37 players. Total neopterin (NP), cortisol and immunoglobulin A were analysed by SCX-high performance liquid chromatography and enzyme linked immunosorbent assay. Global positioning system software provided distance data, while live video analysis provided impact data. All contemporary demands were analysed as events per minute of game time. Forwards were involved in more total impacts, tackles and rucks compared to backs (p cortisol and sIgA. The results indicate distance covered and number of impacts per minute of game time is position-dependent whereas changes in psychophysiological stress are independent. This information can be used to adapt training and recovery interventions to better prepare each position based on the physical requirements of the game.

  2. Linkage mapping of putative regulator genes of barley grain development characterized by expression profiling

    Directory of Open Access Journals (Sweden)

    Wobus Ulrich

    2009-01-01

    Full Text Available Abstract Background Barley (Hordeum vulgare L. seed development is a highly regulated process with fine-tuned interaction of various tissues controlling distinct physiological events during prestorage, storage and dessication phase. As potential regulators involved within this process we studied 172 transcription factors and 204 kinases for their expression behaviour and anchored a subset of them to the barley linkage map to promote marker-assisted studies on barley grains. Results By a hierachical clustering of the expression profiles of 376 potential regulatory genes expressed in 37 different tissues, we found 50 regulators preferentially expressed in one of the three grain tissue fractions pericarp, endosperm and embryo during seed development. In addition, 27 regulators found to be expressed during both seed development and germination and 32 additional regulators are characteristically expressed in multiple tissues undergoing cell differentiation events during barley plant ontogeny. Another 96 regulators were, beside in the developing seed, ubiquitously expressed among all tissues of germinating seedlings as well as in reproductive tissues. SNP-marker development for those regulators resulted in anchoring 61 markers on the genetic linkage map of barley and the chromosomal assignment of another 12 loci by using wheat-barley addition lines. The SNP frequency ranged from 0.5 to 1.0 SNP/kb in the parents of the various mapping populations and was 2.3 SNP/kb over all eight lines tested. Exploration of macrosynteny to rice revealed that the chromosomal orders of the mapped putative regulatory factors were predominantly conserved during evolution. Conclusion We identified expression patterns of major transcription factors and signaling related genes expressed during barley ontogeny and further assigned possible functions based on likely orthologs functionally well characterized in model plant species. The combined linkage map and reference

  3. Estimation of recombination frequency in genetic linkage studies.

    Science.gov (United States)

    Nordheim, E V; O'Malley, D M; Guries, R P

    1983-09-01

    A binomial-like model is developed that may be used in genetic linkage studies when data are generated by a testcross with parental phase unknown. Four methods of estimation for the recombination frequency are compared for data from a single group and also from several groups; these methods are maximum likelihood, two Bayesian procedures, and an ad hoc technique. The Bayes estimator using a noninformative prior usually has a lower mean squared error than the other estimators and because of this it is the recommended estimator. This estimator appears particularly useful for estimation of recombination frequencies indicative of weak linkage from samples of moderate size. Interval estimates corresponding to this estimator can be obtained numerically by discretizing the posterior distribution, thereby providing researchers with a range of plausible recombination values. Data from a linkage study on pitch pine are used as an example.

  4. Research on Medical Insurance Demand and Its Satisfactory Influence Factors -Statistical Analysis Based on Questionnaire Survey%医疗保险需求及满意度的影响因素研究——基于问卷调查的统计分析

    Institute of Scientific and Technical Information of China (English)

    谭湘渝

    2012-01-01

    Based on the analysis of the questionnaire survey, we study the understanding, satisfaction and influence factors of the residents on social medical insurance and commercial health insurance, analyse the influence factors on purchasing commercial health insurance by logistic regression analysis, and find that the educational level and the satisfaction with social medical insurance have big influence on commercial insurance demand.%基于问卷调查的分析,就居民对社会医疗保险和商业医疗保险的了解度、满意度及影响因素进行了研究,采用logistic回归分析研究了商业保险购买意愿的影响因素,发现文化程度及对社会医疗保险的满意度对商业保险需求有较大的影响。

  5. Collaborative Recommendation Algorithm of Web Customer Demand Based on Item Factor Analysis%基于项目因子分析的VVeb客户需求协同推荐算法

    Institute of Scientific and Technical Information of China (English)

    赵宏霞; 王新海; 杨皎平

    2011-01-01

    In order to solve the problem that data overload and data sparsity in collaborative filtering recommendation algorithm, the collaborative recommendation algorithm based on item factor analysis is proposed in this paper. The algorithm reduces the dimensions of item vector by use of factor analysis and gets some representative item factors,which are used to regression analisis of target items to forecast the evaluated items. Finally, experiments show that the algorithm is effective, which provides a new way for future recommendation algorithm research.%为解决协同过滤推荐算法中的数据量过大和数据稀疏性的问题,提出了基于项目因子分析的协同推荐算法.该算法通过采用因子分析将项目向量降维为几个具有代表性的项目因子,然后用这些项目因子对目标项目进行回归分析,进而预测目标客户对待评项目的评分.最后通过实验证明了算法的有效性,为以后研究推荐算法提供了一种新的途径.

  6. Asymmetric epoxidation of cis/trans-β-methylstyrene catalysed by immobilised Mn(salen) with different linkages: heterogenisation of homogeneous asymmetric catalysis.

    Science.gov (United States)

    Zhang, Haidong; Zou, Yu; Wang, Yi-Meng; Shen, Yu; Zheng, Xuxu

    2014-06-16

    Immobilised Mn(salen) catalysts with two different linkages were studied in the asymmetric epoxidation of cis/trans-β-methylstyrene using NaClO as oxidant. The immobilised Mn(salen) complexes inside nanopores can lead to different catalytic behaviour compared with that of homogeneous Jacobsen catalyst. The rigidity of the linkage was found to be a key factor affecting the catalytic performance of immobilised catalysts. The immobilised catalyst with a rigid linkage exhibited comparable chemical selectivity, enantioselectivity and cis/trans ratio of product formation to that obtained with homogeneous Jacobsen catalysts. In contrast, the immobilised catalyst with a flexible linkage gave remarkably lower chemical selectivity, enantioselectivity and inverted cis/trans ratio compared with the results obtained with the homogeneous Jacobsen catalyst and the immobilised catalyst with rigid linkage. Thus, for immobilised Mn(salen) catalysts, a rigid linkage connecting active centres to the support is essential to obtain activity and enantioselectivity as high as those obtained in homogeneous systems.

  7. Software for analysis and manipulation of genetic linkage data.

    Science.gov (United States)

    Weaver, R; Helms, C; Mishra, S K; Donis-Keller, H

    1992-06-01

    We present eight computer programs written in the C programming language that are designed to analyze genotypic data and to support existing software used to construct genetic linkage maps. Although each program has a unique purpose, they all share the common goals of affording a greater understanding of genetic linkage data and of automating tasks to make computers more effective tools for map building. The PIC/HET and FAMINFO programs automate calculation of relevant quantities such as heterozygosity, PIC, allele frequencies, and informativeness of markers and pedigrees. PREINPUT simplifies data submissions to the Centre d'Etude du Polymorphisme Humain (CEPH) data base by creating a file with genotype assignments that CEPH's INPUT program would otherwise require to be input manually. INHERIT is a program written specifically for mapping the X chromosome: by assigning a dummy allele to males, in the nonpseudoautosomal region, it eliminates falsely perceived noninheritances in the data set. The remaining four programs complement the previously published genetic linkage mapping software CRI-MAP and LINKAGE. TWOTABLE produces a more readable format for the output of CRI-MAP two-point calculations; UNMERGE is the converse to CRI-MAP's merge option; and GENLINK and LINKGEN automatically convert between the genotypic data file formats required by these packages. All eight applications read input from the same types of data files that are used by CRI-MAP and LINKAGE. Their use has simplified the management of data, has increased knowledge of the content of information in pedigrees, and has reduced the amount of time needed to construct genetic linkage maps of chromosomes.

  8. Hospitalized prevalence and 5-year mortality for IBD:Record linkage study

    Institute of Scientific and Technical Information of China (English)

    Lori; A; Button; Stephen; E; Roberts; Michael; J; Goldacre; Ashley; Akbari; Sarah; E; Rodgers; John; G; Williams

    2010-01-01

    AIM:To establish the hospitalized prevalence of severe Crohn's disease(CD) and ulcerative colitis(UC) in Wales from 1999 to 2007;and to investigate long-term mortality after hospitalization and associations with social deprivation and other socio-demographic factors.METHODS:Record linkage of administrative inpatient and mortality data for 1467 and 1482 people hospitalised as emergencies for ≥ 3d for CD and UC,respectively.The main outcome measures were hospitalized prevalence,mortality rates and standardize...

  9. Driving demand for broadband networks and services

    CERN Document Server

    Katz, Raul L

    2014-01-01

    This book examines the reasons why various groups around the world choose not to adopt broadband services and evaluates strategies to stimulate the demand that will lead to increased broadband use. It introduces readers to the benefits of higher adoption rates while examining the progress that developed and emerging countries have made in stimulating broadband demand. By relying on concepts such as a supply and demand gap, broadband price elasticity, and demand promotion, this book explains differences between the fixed and mobile broadband demand gap, introducing the notions of substitution and complementarity between both platforms. Building on these concepts, ‘Driving Demand for Broadband Networks and Services’ offers a set of best practices and recommendations aimed at promoting broadband demand.  The broadband demand gap is defined as individuals and households that could buy a broadband subscription because they live in areas served by telecommunications carriers but do not do so because of either ...

  10. Global nitrogen fertilizer supply and demand outlook

    Institute of Scientific and Technical Information of China (English)

    Michel; Prud'homme

    2005-01-01

    This paper presents a brief overview of the world nitrogen fertilizer demand, high-lights trends in the global and regional developments of production capacity and provides a medium-term perspective of the global nitrogen supply/demand balance.

  11. Demands Set Upon Modern Cartographic Visualization

    Directory of Open Access Journals (Sweden)

    Stanislav Frangeš

    2007-05-01

    Full Text Available Scientific cartography has the task to develop and research new methods of cartographic visualization. General demands are set upon modern cartographic visualization, which encompasses digital cartography and computer graphics: legibility, clearness, accuracy, plainness and aesthetics. In this paper, it is explained in detail what demands should be met in order to satisfy the general demands set. In order to satisfy the demand of legibility, one should respect conditions of minimal sizes, appropriate graphical density and better differentiation of known features. Demand of clearness needs to be met by fulfilling conditions of simplicity, contrasting quality and layer arrangement of cartographic representation. Accuracy, as the demand on cartographic visualization, can be divided into positioning accuracy and accuracy signs. For fulfilling the demand of plainness, the conditions of symbolism, traditionalism and hierarchic organization should be met. Demand of aesthetics will be met if the conditions of beauty and harmony are fulfilled.

  12. Mapping autism risk loci using genetic linkage and chromosomal rearrangements

    Science.gov (United States)

    Szatmari, Peter; Paterson, Andrew; Zwaigenbaum, Lonnie; Roberts, Wendy; Brian, Jessica; Liu, Xiao-Qing; Vincent, John; Skaug, Jennifer; Thompson, Ann; Senman, Lili; Feuk, Lars; Qian, Cheng; Bryson, Susan; Jones, Marshall; Marshall, Christian; Scherer, Stephen; Vieland, Veronica; Bartlett, Christopher; Mangin, La Vonne; Goedken, Rhinda; Segre, Alberto; Pericak-Vance, Margaret; Cuccaro, Michael; Gilbert, John; Wright, Harry; Abramson, Ruth; Betancur, Catalina; Bourgeron, Thomas; Gillberg, Christopher; Leboyer, Marion; Buxbaum, Joseph; Davis, Kenneth; Hollander, Eric; Silverman, Jeremy; Hallmayer, Joachim; Lotspeich, Linda; Sutcliffe, James; Haines, Jonathan; Folstein, Susan; Piven, Joseph; Wassink, Thomas; Sheffield, Val; Geschwind, Daniel; Bucan, Maja; Brown, Ted; Cantor, Rita; Constantino, John; Gilliam, Conrad; Herbert, Martha; Lajonchere, Clara; Ledbetter, David; Lese-Martin, Christa; Miller, Janet; Nelson, Stan; Samango-Sprouse, Carol; Spence, Sarah; State, Matthew; Tanzi, Rudolph; Coon, Hilary; Dawson, Geraldine; Devlin, Bernie; Estes, Annette; Flodman, Pamela; Klei, Lambertus; Mcmahon, William; Minshew, Nancy; Munson, Jeff; Korvatska, Elena; Rodier, Patricia; Schellenberg, Gerard; Smith, Moyra; Spence, Anne; Stodgell, Chris; Tepper, Ping Guo; Wijsman, Ellen; Yu, Chang-En; Rogé, Bernadette; Mantoulan, Carine; Wittemeyer, Kerstin; Poustka, Annemarie; Felder, Bärbel; Klauck, Sabine; Schuster, Claudia; Poustka, Fritz; Bölte, Sven; Feineis-Matthews, Sabine; Herbrecht, Evelyn; Schmötzer, Gabi; Tsiantis, John; Papanikolaou, Katerina; Maestrini, Elena; Bacchelli, Elena; Blasi, Francesca; Carone, Simona; Toma, Claudio; Van Engeland, Herman; De Jonge, Maretha; Kemner, Chantal; Koop, Frederieke; Langemeijer, Marjolein; Hijmans, Channa; Staal, Wouter; Baird, Gillian; Bolton, Patrick; Rutter, Michael; Weisblatt, Emma; Green, Jonathan; Aldred, Catherine; Wilkinson, Julie-Anne; Pickles, Andrew; Le Couteur, Ann; Berney, Tom; Mcconachie, Helen; Bailey, Anthony; Francis, Kostas; Honeyman, Gemma; Hutchinson, Aislinn; Parr, Jeremy; Wallace, Simon; Monaco, Anthony; Barnby, Gabrielle; Kobayashi, Kazuhiro; Lamb, Janine; Sousa, Ines; Sykes, Nuala; Cook, Edwin; Guter, Stephen; Leventhal, Bennett; Salt, Jeff; Lord, Catherine; Corsello, Christina; Hus, Vanessa; Weeks, Daniel; Volkmar, Fred; Tauber, Maïté; Fombonne, Eric; Shih, Andy; Meyer, Kacie

    2007-01-01

    Autism spectrum disorders (ASD) are common, heritable neurodevelopmental conditions. The genetic architecture of ASD is complex, requiring large samples to overcome heterogeneity. Here we broaden coverage and sample size relative to other studies of ASD by using Affymetrix 10K single nucleotide polymorphism (SNP) arrays and 1168 families with ≥ 2 affected individuals to perform the largest linkage scan to date, while also analyzing copy number variation (CNV) in these families. Linkage and CNV analyses implicate chromosome 11p12-p13 and neurexins, respectively, amongst other candidate loci. Neurexins team with previously-implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for ASD. PMID:17322880

  13. MNC Strategies and Linkage Effects in Developing Countries

    DEFF Research Database (Denmark)

    Hansen, Michael Wendelboe; Pedersen, Torben; Petersen, Bent

    2007-01-01

    . It is hypothesized that compared to investments undertaken by MNCs following strategies of global integration, investments of MNCs pursuing local responsiveness create more jobs but imply less job upgrading in developing countries. The hypotheses are tested on a sample of Danish MNCs with extensive investments......The paper addresses the question of which implications MNC strategies have to FDI linkage effects in developing countries. Two contrasting MNC strategies reflecting an integration-responsiveness dichotomy are scrutinized as to their job effects on local linkage partners in developing countries...... in developing countries....

  14. Linkage intensity learning approach with genetic algorithm for causality diagram

    Institute of Scientific and Technical Information of China (English)

    WANG Cheng-liang; CHEN Juan-juan

    2007-01-01

    The causality diagram theory, which adopts graphical expression of knowledge and direct intensity of causality, overcomes some shortages in belief network and has evolved into a mixed causality diagram methodology for discrete and continuous variable. But to give linkage intensity of causality diagram is difficult, particularly in many working conditions in which sampling data are limited or noisy. The classic learning algorithm is hard to be adopted. We used genetic algorithm to learn linkage intensity from limited data. The simulation results demonstrate that this algorithm is more suitable than the classic algorithm in the condition of sample shortage such as space shuttle's fault diagnoisis.

  15. Emotional Demands at Work and the Risk of Clinical Depression

    DEFF Research Database (Denmark)

    Vammen, Marianne Agergaard; Mikkelsen, Sigurd; Kolstad, Henrik

    2016-01-01

    OBJECTIVE: This study is a 2-year follow-up study of different dimensions of work-related emotional demands as a predictor for clinical depression. METHODS: In a two-wave study, 3224 (72%) public employees from 474 work-units participated twice by filling in questionnaires. Sixty-two cases of cli....... CONCLUSIONS: The personal perception of emotional demands was a risk factor for clinical depression but specific emotionally demanding work tasks were not.......OBJECTIVE: This study is a 2-year follow-up study of different dimensions of work-related emotional demands as a predictor for clinical depression. METHODS: In a two-wave study, 3224 (72%) public employees from 474 work-units participated twice by filling in questionnaires. Sixty-two cases...... of clinical depression were diagnosed. Emotional demands were examined as perceived and content-related emotional demands, individually reported and work-unit based. Support, meaningful work, and enrichment were considered as potential effect modifiers. RESULTS: Individually reported perceived emotional...

  16. Gravitational demand on the neck musculature during tablet computer use.

    Science.gov (United States)

    Vasavada, Anita N; Nevins, Derek D; Monda, Steven M; Hughes, Ellis; Lin, David C

    2015-01-01

    Tablet computer use requires substantial head and neck flexion, which is a risk factor for neck pain. The goal of this study was to evaluate the biomechanics of the head-neck system during seated tablet computer use under a variety of conditions. A physiologically relevant variable, gravitational demand (the ratio of gravitational moment due to the weight of the head to maximal muscle moment capacity), was estimated using a musculoskeletal model incorporating subject-specific size and intervertebral postures from radiographs. Gravitational demand in postures adopted during tablet computer use was 3-5 times that of the neutral posture, with the lowest demand when the tablet was in a high propped position. Moreover, the estimated gravitational demand could be correlated to head and neck postural measures (0.48 quantitative data about mechanical requirements on the neck musculature during tablet computer use and are important for developing ergonomics guidelines. Practitioner Summary: Flexed head and neck postures occur during tablet computer use and are implicated in neck pain. The mechanical demand on the neck muscles was estimated to increase 3-5 times during seated tablet computer use versus seated neutral posture, with the lowest demand in a high propped tablet position but few differences in other conditions.

  17. Investigating the Stability of Money Demand in Ghana

    Directory of Open Access Journals (Sweden)

    Dennis Nchor

    2016-01-01

    Full Text Available The study examined the demand for broad money and its stability in Ghana. Johansen’s cointegration approach reveals that the variables were non stationary and cointegrated, therefore, an error correction model, ECM was used to determine the factors that influence real money aggregate in Ghana from 1990 to 2014. The study estimated the results using two set of variables for real demand for money: M1 and M2+. This was done given the assumption that the demand for money was equal to the supply of money. The results show that, GDP affects the level of demand for money in the long run while the interest rate affects it in the short run. The error correction term in each of the cases shows that, 18 % of deviations in the real demand for money is corrected annually. The CUSUM tests of parameter stability showed that, the money demand function was stable over the period and the Chow test indicated that there were no structural breaks.

  18. CAUSES AND EFFECTS OF THE GLOBAL DECREASE IN DEMAND

    Directory of Open Access Journals (Sweden)

    Milenko Krajisnik

    2014-12-01

    Full Text Available The current economic crisis has been lasting too long, and particular examples of economic growth and unemployment reduction in some countries have not been the accelerator sufficient for the global recovery. The general level of demand is low, hence so are the investments, although the most powerful economic factors, i.e. the highly developed countries and transnational companies, have the capacities for new investment cycles. This work analyses the causes and effects of decrease in demand, as well as the options available for removal of those causes and revitalization of the effects. One of the main causes of decrease in demand in a long run is the asymmetrical distribution of income which has led to a reduction in purchasing power of a large number of consumers, high debt level and change in demand structure. An additional problem, which can be regarded also as a cause of decline in demand in the short run, is the austerity policy which is being implemented both where necessary and conditioned and where voluntary albeit not necessary. In order to overcome the problem, it is necessary to increase and maintain demand, first initially and then permanently, which is where the state plays an important role.

  19. THE ACCOUNTANT INFORMATION. DEMAND AND OFFER

    OpenAIRE

    Irina CHIRITA; Ioana ZAHEU

    2008-01-01

    The present paper is trying to correlate what Demand and Offer mean, from the economical point of view, which in the end tends towards the demand and offer of the accountant information. The objective of the demand and offer of accountant information is to promo te an efficient financial communication, objective that might be reached through the confrontation of the informational offer with the user’s demand. The information given by the enterprises are the basis of numerous economical and po...

  20. Cache County Water Demand/Supply Model

    OpenAIRE

    Hughes, Trevor C.; Norby, Gregory J.; Thyagarajan, Laxman

    1996-01-01

    This report descibes a municipal water demand forecasting model for use in areas of mixed rural and urban housing types. A series of residential demand functions were derived which forecast water demand based on the ype and density of housing and season. Micro sampling techniques were used to correlate water use data and explanatory variable data for low, medium, and high density housing. The demand functions were...

  1. Study on Customer Demands for Product Innovation

    Institute of Scientific and Technical Information of China (English)

    XIONG Zhiyong; YANG Mingzhong; LI Yibing; LI Jun

    2006-01-01

    In order to improve the satisfaction degree of customers' individual demands on products and reduce the risk of the product innovation, the characteristics of customer demands for product innovation are analyzed, and their type and content are discussed. Then the framework of customer demands acquisition for product innovation is established. Finally, the prototype system of customer demands information acquisition and product customization for product innovation which takes mobile phone as the example is developed successfully.

  2. Analysis of demand for vegetable in Malaysia

    OpenAIRE

    Tey, (John) Yeong-Sheng; Shamsudin, Mad Nasir; Mohamed, Zainalabidin; Abdullah, Amin Mahir; Radam, Alias

    2008-01-01

    The market information is important in facilitating marketing system from production to the downstream. The purpose of this study is to estimate the Malaysian consumers’ demand for vegetables. By using Household Expenditure Survey 2004/05 data, demands for 6 vegetables are analyzed via a multi-stage budgeting system. The estimated demand elasticities show that the demands for all vegetables are found to increase when per capita income rises. Most of the vegetables are found to respond substa...

  3. Chahla Chafiq, Demande au Miroir

    OpenAIRE

    Guilyardi, Catherine

    2016-01-01

    Le regard est omniprésent dans le premier roman en français de Chahla Chafiq, écrivain et sociologue iranienne exilée en France depuis 1983, reconnue pour ses travaux sur l’islamisme. Le personnage central de Demande au miroir, Guita Salim, regarde la vie de sa fenêtre. « Entre la fenêtre et le voir, il y a toujours un écart », écrit Forough Farrokhzâd, poétesse persane qui illumina les années 1950-1960, dont la poésie traverse ce roman. Adolescente, dans une ruelle de Téhéran, la jeune héroï...

  4. Managing Demands for Social Engagement

    DEFF Research Database (Denmark)

    Glerup, Cecilie

    pressure on the biotech research organizations that find themselves in a jumble of demands to engage themselves with society. Mccarthy and Kelty, for instance, quote a nano-technologist for saying that he is afraid of “too much responsibility” (2010: 407). Based on a laboratory ethnography, this paper...... general public’ or ‘the troops’. The other lab has many diffuse ‘side-activities’ with bio-hackers, government and policy groups, but partly seems to engage in order to stay ahead of policy-makers and protect their core activity, which they find to be ‘basic research’. The paper finally argues...... that the way society’s expectations are managed have severe implications on how research projects are organized and prioritized among the organizations’ employees....

  5. 7 CFR 987.11 - Trade demand.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Trade demand. 987.11 Section 987.11 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... RIVERSIDE COUNTY, CALIFORNIA Order Regulating Handling Definitions § 987.11 Trade demand. Trade demand means...

  6. 7 CFR 3560.709 - Demand letter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Demand letter. 3560.709 Section 3560.709 Agriculture... DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.709 Demand letter. (a) If a... repayment schedule, the Agency will send the borrower a demand letter specifying: (1) The amount of...

  7. 7 CFR 981.21 - Trade demand.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Trade demand. 981.21 Section 981.21 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Definitions § 981.21 Trade demand. Trade demand means the quantity of almonds...

  8. 31 CFR 29.511 - Demand letters.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Demand letters. 29.511 Section 29.511... Overpayments § 29.511 Demand letters. Except as provided in § 29.516(e), before starting collection action to recover an overpayment, the Benefits Administrator must send a demand letter that informs the debtor in...

  9. Genetic algorithms in seasonal demand forecasting

    OpenAIRE

    Chodak, Grzegorz; Kwaśnicki, Witold

    2000-01-01

    The method of forecasting seasonal demand applying genetic algorithm is presented. Specific form of used demand function is shown in the first section of the article. Next the method of identification of the function parameters using genetic algorithms is discussed. In the final section an example of applying proposed method to forecast real demand process is shown.

  10. Energy Demands and Efficiency Strategies in Data Center Buildings

    Science.gov (United States)

    Shehabi, Arman

    2009-01-01

    Information technology (IT) is becoming increasingly pervasive throughout society as more data is digitally processed, stored, and transferred. The infrastructure that supports IT activity is growing accordingly, and data center energy demands have increased by nearly a factor of four over the past decade. This dissertation investigates how…

  11. Satisfying the demand for financial information in public traded companies

    DEFF Research Database (Denmark)

    Holm, Claus

    to be an ever increasing factor. The financial reporting has to fulfill the requirements for official fillings to the stock exchange and the capital market as well as more voluntary Internet reporting to make annual, semi-annual and even quarterly reports publicly available. This demand for extensive...

  12. Modified Normal Demand Distributions in (R,S)-Inventory Models

    NARCIS (Netherlands)

    Strijbosch, L.W.G.; Moors, J.J.A.

    2003-01-01

    To model demand, the normal distribution is by far the most popular; the disadvantage that it takes negative values is taken for granted.This paper proposes two modi.cations of the normal distribution, both taking non-negative values only.Safety factors and order-up-to-levels for the familiar (R,

  13. Descriptive documentation for New Mexico electricity econometric final demand model

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, J.D.; Ben-David, S.

    1981-01-01

    A mathematical model is developed for computing consumption and residential electric power demands for New Mexico. Factors considered in developing the model included: number of electric utility customers, past consumption data; household devices using electric power and their energy efficiencies; climatic conditions; and power costs. (LCL)

  14. Cost Effectiveness and Demand for Medical Services among Rural ...

    African Journals Online (AJOL)

    FIRST LADY

    ... 2010:www.afrrevjo.com. 306. Indexed African Journals Online: www.ajol.info .... waiting time, income of consumers, access to care in turns of availability of ... Factors affecting health care services demand are expressed in Figure 1. ▫ Modern ...

  15. Demand for outpatient healthcare: empirical findings from rural India.

    Science.gov (United States)

    Sarma, Sisira

    2009-01-01

    Price, income and health status are likely to affect the demand for healthcare in developing countries, and their quantitative effects are unclear in the literature. Some studies report that prices are not important determinants, while others conclude that prices are important determinants of the demand for healthcare. Knowledge of the extent to which price, income and health status affect the demand for healthcare is crucial for the design of effective health policy in developing countries. To examine the role of monetary and non-monetary price, income, and a variety of individual- and household-specific characteristics on the demand for healthcare in rural India. Utilizing micro data from the 52nd round of India's National Sample Survey, a variable choice set based on geographical location, price, income and the severity of illness was constructed to reflect the underlying true choice-generating process in rural India. Nested multinomial logit models were estimated and simulations with respect to prices and income were conducted to estimate price and income elasticities. Contrary to many earlier studies on the demand for healthcare in developing countries, it was found that prices and income were statistically significant determinants of the choice of healthcare provider by individuals in rural India. Demand for healthcare was found to be price and income inelastic, corroborating the findings from other developing countries. Distance to formal healthcare facilities negatively affected the demand for outpatient healthcare, an effect that was mitigated as access to transportation improved. Age, sex, healthy days, educational status of the household members and the number of children and adults living in the household also affected the choice of healthcare provider in rural India. After controlling for a number of sociodemographic factors, it was found that prices, income and distance are statistically significant determinants of the provider chosen by individuals

  16. 考虑时间和价格因素的Web客户需求协同推荐模型%Collaborative Filtering Recommendation Model of Web Customer Demand Considering Time and Price Factors

    Institute of Scientific and Technical Information of China (English)

    赵宏霞; 杨皎平; 万君

    2011-01-01

    The collaborative filtering recommendation algorithm is the widely used technology in the personalized e-commerce recommendation system. However, the traditional recommendation algorithm neglected trading hours and product pricing when recommended products, which led to the lower quality recommended. To solve this problem, a collaborative filtering model considering time and price factors is proposed in this paper, and experiments show that the improvement of algorithm is most effective when time and price factors are taken into account in the calculation of Pearson correlation coefficient.%协同过滤推荐算法是电子商务个性化推荐系统中采用最为广泛的推荐技术,但是传统的推荐方法在进行商品推荐时忽略了交易时间和产品的价格因素,从而导致推荐质量下降.针对这一问题,提出了考虑时间和价格因素的协同过滤模型,通过实验表明在计算Pearson相关系数时考虑时间和价格因素对算法的改进最为有效.

  17. 中国电力行业周期波动特征及电力需求影响因素分析——基于景气分析及误差修正模型的研究%Characteristics of Electricity Industry Cycle Fluctuation and Influential Factors of Electricity Demand Based on Business Analysis and the Error Correction Model

    Institute of Scientific and Technical Information of China (English)

    刘畅; 高铁梅

    2011-01-01

    2008年的国际金融危机使我国电力消费需求快速下降,而宏观经济却保持正增长,这一现象使人们怀疑数据的真实性.本文使用景气分析方法建立了电力行业景气指数,分析了2000年以来电力行业的周期波动特征,并使用月度数据建立了误差修正模型,研究了影响电力行业波动的长期经济因素和短期动态调整效应.研究结果表明,电力行业景气与宏观经济波动具有一致的变化趋势,但波动幅度不同;工业经济增长、高耗电行业结构、库存及电力需求之间存在稳定的长期均衡关系,工业经济增长和经济结构重型化是影响电力需求的最重要因素,库存与电力需求之间存在显著负相关关系;从金融危机时期电力行业波动的谷底来看,工业经济下滑和高耗电行业结构变化是电力行业周期波动出现深谷的主要原因,特别地,由于市场需求变化引起的库存调整能够导致电力需求更剧烈的波动;无论是长期还是短期,电价对电力需求的影响都不显著.%Due to the outbreak of the global financial crisis and its impact on the real economy in China, China' s electricity consumption demand reduced significantly. In the second half of year 2008, the contradiction that electricity consumption declination was accompanied with GDP growth occurred. The authors examined characteristics of cyclical fluctuation of the electricity industry, the relationship between the electricity industry cycle and macro economic cycle, and factors affecting changes in electricity consumption. Using monthly macro and performance data across the period January 1999-November 2009, the authors first constructed the business indexes for China' s electricity industry with business analysis methods to analyze characteristics of the electricity industry cycle and fluctuation since 2000. With the time difference correlation analysis and cyclical pattern matching methods, the authors selected

  18. EDITORIAL: Photonic materials on demand Photonic materials on demand

    Science.gov (United States)

    Zheludev, Nikolay; Padilla, Willie J.; Brener, Igal

    2012-11-01

    As David Payne famously said, 'we never have a photonic material that we want...'. This has changed with the proliferation of nanotechnology. Metamaterials—artificial media structured on a sub-wavelength scale—offer a radical paradigm for the engineering of optical properties. Some remarkable advances have been possible with metamaterials. These include, for instance, negative-index media that refract light in the opposite direction from that of conventional materials, chiral materials that rotate the polarization state of light hundreds of thousands of times more strongly than natural optical crystals, and structured thin films with remarkably strong dispersion that can slow light in much the same way as resonant atomic systems with electromagnetically induced transparency. The research agenda is now shifting towards achieving tunable and switchable functionalities with metamaterials [1] where the goal is, paraphrasing Dave Payne, 'to have on demand the photonic material that we want'. The papers in this Journal of Optics special issue explore and review the different approaches to both switching and tuning of metamaterial properties through exploiting effects such as phase conjugation, intense photo-excitation and photoconductivity, the use of electro-optical effects in conductive oxides, the exploitation global quantum coherency and resonantly coupled classical resonator and quantum structures, hybridization with gain media and the manipulation with shapes and constitution of the complex metamolecules and metamaterial reliefs by design, or using MEMS actuation. References [1] Zheludev N I and Kivshar Y 2012 From metamaterials to metadevices Nature Mater.11 917

  19. SNPs, linkage disequilibrium, and chronic mountain sickness in Tibetan Chinese

    Directory of Open Access Journals (Sweden)

    Buroker NE

    2017-07-01

    Full Text Available Norman E Buroker,1 Xue-Han Ning,1,2,† Zhao-Nian Zhou,3 Kui Li,4 Wei-Jun Cen,4 Xiu-Feng Wu,3 Wei-Zhong Zhu,5 C Ronald Scott,1 Shi-Han Chen1 1Department of Pediatrics, University of Washington, 2Division of Cardiology, Seattle Children’s Hospital Research Foundation, Seattle, WA, USA; 3Laboratory of Hypoxia Physiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; 4Lhasa People Hospital, Lhasa, Tibet; 5Center for Cardiovascular Biology and Regenerative Medicine, University of Washington, Seattle, WA, USA †Xue-Han Ning passed away on April 20, 2015 Abstract: Chronic mountain sickness (CMS is estimated at 1.2% in Tibetans living at the Qinghai–Tibetan Plateau. Eighteen single-nucleotide polymorphisms (SNPs from nine nuclear genes that have an association with CMS in Tibetans have been analyzed by using pairwise linkage disequilibrium (LD. The SNPs included are the angiotensin-converting enzyme (rs4340, the angiotensinogen (rs699, and the angiotensin II type 1 receptor (AGTR1 (rs5186 from the renin–angiotensin system. A low-density lipoprotein apolipoprotein B (rs693 SNP was also included. From the hypoxia-inducible factor oxygen signaling pathway, the endothetal Per-Arnt-Sim domain protein 1 (EPAS1 and the egl nine homolog 1 (ENGL1 (rs480902 SNPs were included in the study. SNPs from the vascular endothelial growth factor (VEGF signaling pathway included are the v-akt murine thymoma viral oncogene homolog 3 (rs4590656 and rs2291409, the endothelial cell nitric oxide synthase 3 (rs1007311 and rs1799983, and the (VEGFA (rs699947, rs34357231, rs79469752, rs13207351, rs28357093, rs1570360, rs2010963, and rs3025039. An increase in LD occurred in 40 pairwise comparisons, whereas a decrease in LD was found in 55 pairwise comparisons between the controls and CMS patients. These changes were found to occur within and between signaling pathways, which suggests that there is an interaction between SNP

  20. DEVELOPMENT OF MILK CONSUMPTION AND MARKETING ANALYSIS OF ITS DEMAND

    OpenAIRE

    Marta Habánová; Ľubica Kubicová

    2012-01-01

    The strategy of most households is to eliminate the negative effects of economic changes related mainly to the economic crisis by mobilizing available resources and reducing costs, but which cloud lead to a decrease in food consumption and changes in consumption patterns. Pensions and prices are factors that shape the demand for food and other estates. Both of these factors guarantee the economic viability of nutrition. Paper analyzes the development of the of milk consumption and level of it...

  1. Exploring Demand Charge Savings from Commercial Solar

    Energy Technology Data Exchange (ETDEWEB)

    Darghouth, Naim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Barbose, Galen [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mills, Andrew [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wiser, Ryan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gagnon, Pieter [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-07-31

    Commercial retail electricity rates commonly include a demand charge component, based on some measure of the customer’s peak demand. Customer-sited solar PV can potentially reduce demand charges, but the magnitude of these savings can be difficult to predict, given variations in demand charge designs, customer loads, and PV generation profiles. Moreover, depending on the circumstances, demand charges from solar may or may not align well with associated utility cost savings. Lawrence Berkeley National Laboratory (Berkeley Lab) and the National Renewable Energy Laboratory (NREL) are collaborating in a series of studies to understand how solar PV can reduce demand charge levels for a variety of customer types and demand charges designs. Previous work focused on residential customs with solar. This study, instead, focuses on commercial customers and seeks to understand the extent and conditions under which rooftop can solar reduce commercial demand charges. To answer these questions, we simulate demand charge savings for a broad range of commercial customer types, demand charge designs, locations, and PV system characteristics. This particular analysis does not include storage, but a subsequent analysis in this series will evaluate demand charge savings for commercial customers with solar and storage.

  2. Innovation and society: in search of new linkages

    NARCIS (Netherlands)

    1991-01-01

    This report is based on the spring conference "Innovation and Society: in Search of New Linkages" organized by the Six Countries Programme on April 16 and 17 1991 in Noordwijk aan Zee in The Netherlands. The hosts for this conference were the Netherlands delegates in the Six Countries Programne: the

  3. Linkage Disequilibrium Decay and Haplotype Block Structure in the Pig

    NARCIS (Netherlands)

    Amaral, A.J.; Megens, H.J.W.C.; Crooijmans, R.P.M.A.; Heuven, H.C.M.; Groenen, M.A.M.

    2008-01-01

    Linkage disequilibrium (LD) may reveal much about domestication and breed history. Ail investigation was conducted, to analyze the extent of LD, haploblock partitioning, and haplotype diversity within haploblocks across several pig breeds from China and Europe and in European wild boar. In total, 37

  4. Linkage disequilibrium and its expectation in human populations.

    Science.gov (United States)

    Sved, John A

    2009-02-01

    Abstract Linkage disequilibrium (LD), the association in populations between genes at linked loci, has achieved a high degree of prominence in recent years, primarily because of its use in identifying and cloning genes of medical importance. The field has recently been reviewed by Slatkin (2008). The present article is largely devoted to a review of the theory of LD in populations, including historical aspects.

  5. International Environmental Problems, Issue Linkage and the European Union

    NARCIS (Netherlands)

    Kroeze-Gil, J.

    2003-01-01

    This thesis explores the circumstances under which issue linkage can be applied to achieve cooperation on international environmental problems in general and on environmental problems in the European Union in particular. A major topic in this thesis is the development and analysis of cooperative and

  6. Recombination patterns reveal information about centromere location on linkage maps

    DEFF Research Database (Denmark)

    Limborg, Morten T.; McKinney, Garrett J.; Seeb, Lisa W.

    2016-01-01

    . mykiss) characterized by low and unevenly distributed recombination – a general feature of male meiosis in many species. Further, a high frequency of double crossovers along chromosome arms in barley reduced resolution for locating centromeric regions on most linkage groups. Despite these limitations...

  7. A consensus linkage map of the chicken genome

    NARCIS (Netherlands)

    Groenen, M.A.M.; Cheng, H.H.; Bumstead, N.; Benkel, B.; Briles, E.; Burt, D.W.; Burke, T.; Dodgson, J.; Hillel, J.; Lamont, S.; Ponce, de F.A.; Soller, M.

    2000-01-01

    A consensus linkage map has been developed in the chicken that combines all of the genotyping data from the three available chicken mapping populations. Genotyping data were contributed by the laboratories that have been using the East Lansing and Compton reference populations and from the Animal Br

  8. A consensus linkage map of the chicken genome

    NARCIS (Netherlands)

    Groenen, M.A.M.; Cheng, H.H.; Bumstead, N.; Benkel, B.; Briles, E.; Burt, D.W.; Burke, T.; Dodgson, J.; Hillel, J.; Lamont, S.; Ponce, de F.A.; Soller, M.

    2000-01-01

    A consensus linkage map has been developed in the chicken that combines all of the genotyping data from the three available chicken mapping populations. Genotyping data were contributed by the laboratories that have been using the East Lansing and Compton reference populations and from the Animal

  9. Bayesian linkage analysis of categorical traits for arbitrary pedigree designs.

    Directory of Open Access Journals (Sweden)

    Abra Brisbin

    Full Text Available BACKGROUND: Pedigree studies of complex heritable diseases often feature nominal or ordinal phenotypic measurements and missing genetic marker or phenotype data. METHODOLOGY: We have developed a Bayesian method for Linkage analysis of Ordinal and Categorical traits (LOCate that can analyze complex genealogical structure for family groups and incorporate missing data. LOCate uses a Gibbs sampling approach to assess linkage, incorporating a simulated tempering algorithm for fast mixing. While our treatment is Bayesian, we develop a LOD (log of odds score estimator for assessing linkage from Gibbs sampling that is highly accurate for simulated data. LOCate is applicable to linkage analysis for ordinal or nominal traits, a versatility which we demonstrate by analyzing simulated data with a nominal trait, on which LOCate outperforms LOT, an existing method which is designed for ordinal traits. We additionally demonstrate our method's versatility by analyzing a candidate locus (D2S1788 for panic disorder in humans, in a dataset with a large amount of missing data, which LOT was unable to handle. CONCLUSION: LOCate's accuracy and applicability to both ordinal and nominal traits will prove useful to researchers interested in mapping loci for categorical traits.

  10. AFLP linkage map of the Japanese quail Coturnix japonica

    Directory of Open Access Journals (Sweden)

    Beaumont Catherine

    2003-09-01

    Full Text Available Abstract The quail is a valuable farm and laboratory animal. Yet molecular information about this species remains scarce. We present here the first genetic linkage map of the Japanese quail. This comprehensive map is based solely on amplified fragment length polymorphism (AFLP markers. These markers were developed and genotyped in an F2 progeny from a cross between two lines of quail differing in stress reactivity. A total of 432 polymorphic AFLP markers were detected with 24 TaqI/EcoRI primer combinations. On average, 18 markers were produced per primer combination. Two hundred and fifty eight of the polymorphic markers were assigned to 39 autosomal linkage groups plus the ZW sex chromosome linkage groups. The linkage groups range from 2 to 28 markers and from 0.0 to 195.5 cM. The AFLP map covers a total length of 1516 cM, with an average genetic distance between two consecutive markers of 7.6 cM. This AFLP map can be enriched with other marker types, especially mapped chicken genes that will enable to link the maps of both species and make use of the powerful comparative mapping approach. This AFLP map of the Japanese quail already provides an efficient tool for quantitative trait loci (QTL mapping.

  11. Analysis of Linkage Effects among Currency Networks Using REER Data

    Directory of Open Access Journals (Sweden)

    Haishu Qiao

    2015-01-01

    Full Text Available We modeled the currency networks through the use of REER (real effective exchange rate instead of a bilateral exchange rate in order to overcome the confusion in selecting base currencies. Based on the MST (minimum spanning tree approach and the rolling-window method, we constructed time-varying and correlation-based networks with which we investigate the linkage effects among different currencies. In particular, and as the source of empirical data, we chose the monthly REER data for a set of 61 major currencies during the period from 1994 to 2014. The study demonstrated that obvious linkage effects existed among currency networks and the euro (EUR was confirmed as the predominant world currency. Additionally, we used the rolling-window method to investigate the stability of linkage effects, doing so by calculating the mean correlations and mean distances as well as the normalized tree length and degrees of those currencies. The results showed that financial crises during the study period had a great effect on the currency network’s topology structure and led to more clustered currency networks. Our results suggested that it is more appropriate to estimate the linkage effects among currency networks through the use of REER data.

  12. Typology of Empirical Attributes: Dissimilarity Linkage Analysis (DLA).

    Science.gov (United States)

    Dubin, Robert; Champoux, Joseph E.

    Dissimilarity Linkage Analysis (DLA) is an extremely simple procedure for developing a typology from empirical attributes that permits the clustering of entities. First the procedure develops a taxonomy of types from empirical attributes possessed by entities in the sample. Second, the procedure assigns entities to one, and only one, type in the…

  13. Learning and Competence Building through Cross-cultural Linkages

    DEFF Research Database (Denmark)

    Sørensen, Olav Jull

    2006-01-01

    The aim of the chapter is to study upgrading of companies in developing countries in a learning perspective. Both formal and experiential and tacit knowledge is discussed. Learning effects of different management modes, expatriates, linkages to customers and suppliers are discussed as are learnin...

  14. Innovation and inter-firm linkages : new implications for policy

    NARCIS (Netherlands)

    Nooteboom, B

    1999-01-01

    This article discusses the implications for competition, innovation and learning of different forms of inter-firm linkage, ways to govern them, different 'generic systems' of innovation, and government policy. It employs a transformed theory of transactions that can deal with innovation and learning

  15. Broad scan linkage analysis in a large Tourette family pedigree

    Energy Technology Data Exchange (ETDEWEB)

    Peiffer, A.; Leppert, M. [Univ. of Utah Health Sciences Center, Salt Lake City, UT (United States); Wetering, B.J.M. van der [Univ. Hospital Rotterdam (Netherlands)

    1994-09-01

    Attempts to find a gene causing Tourette syndrome (TS) using linkage analysis have been unsuccessful even though as much as 65% of the autosomal genetic map has been excluded by the pooled results from several laboratories collaborating worldwide. One reason for this failure may be the misclassification of affection status of marry-in spouses. Specifically, we have found that six unrelated spouses in our Utah TS pedigree suffer from TS, obsessive-compulsive disorder or chronic motor tics. In light of these findings we decided to conduct a complete genomic scan from this Utah kindred with polymorphic markers in three related sibships in which there was no assortative mating. A linkage study assuming autosomal dominant inheritance was done using tetranucleotide repeat markers developed at the University of Utah. We selected markers that were less than 300 bp in size and that gave a heterozygosity of over 70% upon analysis in 4 CEPH families. Results to date with 95 markers run at an interval of 30 cM (covering 61% of the genome) show no evidence of linkage. We intend to extend the coverage to 100% of the genome. Pending completion of this scan, failure to provide evidence of linkage in our TS pedigree might then be attributed to phenotypic misclassification or erroneous assumptions regarding the genetic model of transmission.

  16. Stability of Money Demand Function in Pakistan

    Directory of Open Access Journals (Sweden)

    Haroon Sarwar

    2013-09-01

    Full Text Available The role, which money demand function plays in monetary policy formulation has attracted a lot of research studies to analyze this macroeconomic phenomenon. In the wake of current global and local economic and political upheavals, it is imperative to revisit the stability of money demand function. The study used the time series data and applied latest econometric techniques to find out the long run and short run money demand relationship. Moreover, all the three official monetary aggregates were used for finding out the most stable monetary demand relationship, which could provide correct signals for monetary policy formulation. The study found that broader monetary aggregate (M2 was the proper aggregate, which provided stable money demand function for Pakistan. The real GDP was positively related to the demand for real balances, while opportunity cost of money was negatively related. The study found that the role of financial innovation, in explaining the demand for money warrants attention in formulating monetary policy.

  17. Demands of immigration among Chinese immigrant nurses.

    Science.gov (United States)

    Ma, Amy X; Griffin, Mary T Quinn; Capitulo, Katie L; Fitzpatrick, Joyce J

    2010-10-01

    The purpose of this study was to identify the demands of immigration among Chinese nurses that have immigrated to the USA. The relationship between the demands of immigration and length of stay in the USA was investigated also. A descriptive correlational study design was used. A convenience sample of 128 nurses was recruited. A self-administered survey was conducted using the demands of immigration scale developed by Aroian, along with a demographic questionnaire. The results showed Chinese immigrant nurses have high demands of immigration. There were significant negative relationships between the demands of immigration and length of stay in the USA. Immigration demands decreased as length of stay increased but remained high even for those who had been in the USA for > 5 years. This information is vital to health-care agencies designing and implementing adaptation programmes targeting these demands to facilitate Chinese nurses' adaptation process.

  18. 山东省农村居民消费需求影响因素实证研究%Empirical Research on Influencing Factors of Consuming Demand of Rural Residents in Shandong Province

    Institute of Scientific and Technical Information of China (English)

    胡保玲; 孙立娜

    2012-01-01

    扩大农村居民消费对提升山东省经济发展至关重要。文章建立农村居民消费需求固定效应变截距模型,运用1998—2010年的面板数据实证研究了经济、社会与心理诸因素与农村居民消费之间的关系。结果发现,工资性收入、财产性收入、人均储蓄余额、社会保障支出和消费习惯对农村居民消费呈现正的影响效应。%It is of great importance to enlarge the consumption of rural residents for the economic develop- ment of Shandong Province. By constructing rural consuming fixed effects variable intercept model, this thesis re- searches the relationship between economic, social, and psychological factors and rural consumption with the help of panel data from 1998 to 2010. The result shows that there is a positive influence between wage incomes, property incomes, per capita savings balance, social security spending and consuming habits and rural consumption.

  19. The phenotypic difference discards sib-pair QTL linkage information

    Energy Technology Data Exchange (ETDEWEB)

    Wright, F.A. [Univ. of California, San Diego, CA (United States)]|[Univ. of Texas, El Paso, TX (United States)

    1997-03-01

    Kruglyak and Lander provide an important synthesis of methods for (IBD) sib-pair linkage mapping, with an emphasis on the use of complete multipoint inheritance information for each sib pair. These procedures are implemented in the computer program MAPMAKER/SIBS, which performs interval mapping for dichotomous and quantitative traits. The authors present three methods for mapping quantitative trait loci (QTLs): a variant of the commonly used Haseman-Elston regression approach, a maximum-likelihood procedure involving variance components, and a rank-based nonparametric procedure. These approaches and related work use the magnitude of the difference in the sibling phenotype values for each sib pair as the observation for analysis. Linkage is detected if siblings sharing more alleles IBD have similar phenotypes (i.e., a small difference in the phenotype values), while siblings sharing fewer alleles IBD have less similar phenotypes. Such techniques have been used to detect linkage for a number of quantitative traits. However, the exclusive reliance on the phenotypic differences may be due in large part to historical inertia. A likelihood argument is presented here to show that, under certain classical assumptions, the phenotypic differences do not contain the full likelihood information for QTL mapping. Furthermore, considerable gains in power to detect linkage can be achieved with an expanded likelihood model. The development here is related to previous work, which incorporates the full set of phenotypic data using likelihood and robust quasi-likelihood methods. The purpose of this letter is not to endorse a particular approach but to spur research in alternative and perhaps more powerful linkage tests. 17 refs.

  20. BATMAN: MOS Spectroscopy on Demand

    Science.gov (United States)

    Molinari, E.; Zamkotsian, F.; Moschetti, M.; Spano, P.; Boschin, W.; Cosentino, R.; Ghedina, A.; González, M.; Pérez, H.; Lanzoni, P.; Ramarijaona, H.; Riva, M.; Zerbi, F.; Nicastro, L.; Valenziano, L.; Di Marcantonio, P.; Coretti, I.; Cirami, R.

    2016-10-01

    Multi-Object Spectrographs (MOS) are the major instruments for studying primary galaxies and remote and faint objects. Current object selection systems are limited and/or difficult to implement in next generation MOS for space and ground-based telescopes. A promising solution is the use of MOEMS devices such as micromirror arrays, which allow the remote control of the multi-slit configuration in real time. TNG is hosting a novelty project for real-time, on-demand MOS masks based on MOEMS programmable slits. We are developing a 2048×1080 Digital-Micromirror-Device-based (DMD) MOS instrument to be mounted on the Galileo telescope, called BATMAN. It is a two-arm instrument designed for providing in parallel imaging and spectroscopic capabilities. With a field of view of 6.8×3.6 arcmin and a plate scale of 0.2 arcsec per micromirror, this astronomical setup can be used to investigate the formation and evolution of galaxies. The wavelength range is in the visible and the spectral resolution is R=560 for a 1 arcsec object, and the two arms will have 2k × 4k CCD detectors. ROBIN, a BATMAN demonstrator, has been designed, realized and integrated. We plan to have BATMAN first light by mid-2016.

  1. Physiological demands of competitive basketball.

    Science.gov (United States)

    Narazaki, K; Berg, K; Stergiou, N; Chen, B

    2009-06-01

    The aim of this study was to assess physiological demands of competitive basketball by measuring oxygen consumption (VO2) and other variables during practice games. Each of 12 players (20.4 +/- 1.1 years) was monitored in a 20-min practice game, which was conducted in the same way as actual games with the presence of referees and coaches. VO2 was measured by a portable system during the game and blood lactate concentration (LA) was measured in brief breaks. Subjects were also videotaped for time-motion analysis. Female and male players demonstrated respective VO2 of 33.4 +/- 4.0 and 36.9 +/- 2.6 mL/kg/min and LA of 3.2 +/- 0.9 and 4.2 +/- 1.3 mmol/L in the practice games (P>0.05). They spent 34.1% of play time running and jumping, 56.8% walking, and 9.0% standing. Pre-obtained VO(2max) was correlated to VO(2) during play (r=0.673) and to percent of duration for running and jumping (r=0.935 and 0.962 for females and males, respectively). This study demonstrated a greater oxygen uptake for competitive basketball than that estimated based on a previous compendium. The correlation between aerobic capacity and activity level suggests the potential benefit of aerobic conditioning in basketball.

  2. The metabolic demands of kayaking: a review.

    Science.gov (United States)

    Michael, Jacob S; Rooney, Kieron B; Smith, Richard

    2008-03-01

    Flat-water kayaking is one of the best-known competitive canoeing disciplines in Australia and across the European countries. From a stationary start, paddlers are required to paddle their kayaks with maximal effort along the length of the competing distance. The ultimate criterion of kayak performance is the time taken to paddle a designated competition distance. In flat-water racing, events are contested over 500 and 1000 metres. To approximate the ultimate criterion over these distances, the velocity of the kayak should be measured. Furthermore, other factors that affect performance, such as force, power, technique and aerobic fitness, would all provide a valuable insight to the success of the kayak paddler. Specific research performed examining the physiological demands on kayak paddlers demonstrate high levels of both aerobic power and anaerobic capacity. It is the purpose if this review to present the published physiological data relating to men's and women's kayaking. With a number of recent publications, a need for an updated review is necessary. The present review summarises recent data on anthropometrics, physiological characteristics of successful and unsuccessful kayak athletes and methods of physiological testing. Due to the fact that more data have been reported for male competitors than for their female counterparts, the demands of kayaking on male athletes will be the main focus for this review. The review also suggests areas for future research into flatwater kayaking performance. Understanding the physiological requirements of kayaking can assist coaches and athletes in a number of ways. During competition or training, such information is helpful in the selection of appropriate protocols and metabolic indices to monitor an athlete's performance improvements and assess an athlete's suitability for a particular race distance. Furthermore, it may aid the coach in the development of more specific training programs for their athletes. Key points

  3. Identification of a Linkage Disequilibrium Block in Chromosome 1q Associated With BMD in Premenopausal White Women

    OpenAIRE

    Ichikawa, Shoji; Koller, Daniel L.; Curry, Leah R.; Lai, Dongbing; Xuei, Xiaoling; Pugh, Elizabeth W; Tsai, Ya-Yu; Doheny, Kimberly F.; Edenberg, Howard J.; Hui, Siu L.; Foroud, Tatiana; Peacock, Munro; Econs, Michael J.

    2008-01-01

    Osteoporosis is a complex disease with both genetic and environmental risk factors. A major determinant of osteoporotic fractures is peak BMD obtained during young adulthood. We previously reported linkage of chromosome 1q (LOD = 4.3) with variation in spinal areal BMD in healthy premenopausal white women. In this study, we used a two-stage genotyping approach to identify genes in the linked region that contributed to the variation of femoral neck and lumbar spine areal BMD. In the first stag...

  4. Application of short-term water demand prediction model to Seoul.

    Science.gov (United States)

    Joo, C N; Koo, J Y; Yu, M J

    2002-01-01

    To predict daily water demand for Seoul, Korea, the artificial neural network (ANN) was used. For the cross correlation, the factors affecting water demand such as maximum temperature, humidity, and wind speed as natural factors, holidays as a social factor and daily demand 1 day before were used. From the results of learning using various hidden layers and units in order to establish the structure of optimal ANN, the case of 3 hidden layers and numbers of unit with the same number of input factors showed the best result and, therefore, it was applied to seasonal water demand prediction. The performance of ANN was compared with a multiple regression method. We discuss the representation ability of the model building process and the applicability of the ANN approach for the daily water demand prediction. ANN provided reasonable results for time series prediction.

  5. THE METABOLIC DEMANDS OF KAYAKING: A REVIEW

    Directory of Open Access Journals (Sweden)

    Jacob S. Michael

    2008-03-01

    Full Text Available Flat-water kayaking is one of the best-known competitive canoeing disciplines in Australia and across the European countries. From a stationary start, paddlers are required to paddle their kayaks with maximal effort along the length of the competing distance. The ultimate criterion of kayak performance is the time taken to paddle a designated competition distance. In flat-water racing, events are contested over 500 and 1000 metres. To approximate the ultimate criterion over these distances, the velocity of the kayak should be measured. Furthermore, other factors that affect performance, such as force, power, technique and aerobic fitness, would all provide a valuable insight to the success of the kayak paddler. Specific research performed examining the physiological demands on kayak paddlers demonstrate high levels of both aerobic power and anaerobic capacity. It is the purpose if this review to present the published physiological data relating to men's and women's kayaking. With a number of recent publications, a need for an updated review is necessary. The present review summarises recent data on anthropometrics, physiological characteristics of successful and unsuccessful kayak athletes and methods of physiological testing. Due to the fact that more data have been reported for male competitors than for their female counterparts, the demands of kayaking on male athletes will be the main focus for this review. The review also suggests areas for future research into flatwater kayaking performance. Understanding the physiological requirements of kayaking can assist coaches and athletes in a number of ways. During competition or training, such information is helpful in the selection of appropriate protocols and metabolic indices to monitor an athlete's performance improvements and assess an athlete's suitability for a particular race distance. Furthermore, it may aid the coach in the development of more specific training programs for their

  6. [Study on elasticity of medical service demand at the township level in China].

    Science.gov (United States)

    Shi, Hong-xing; Lv, Jun; Xie, Yi-ping; Wang, Ying; Jia, Jin-zhong; Chang, Feng-shui; Duan, Lin; Sun, Mei; Wang, Zhi-feng; Hao, Mo

    2010-06-18

    To find out the economic laws regulating medical service demand in accordance with influencing factors at the township level, thus to provide references for further adjusting the medical service demand reasonably in the future. The model of medical service demand was established to measure the elasticity of demand in 49 township health clinics in 1995, 1999, 2003 and 2007. The price elasticity of outpatient and inpatient demand was stable during the four periods, and the average value was -0.029 and -0.132 respectively; the average value of income elasticity was 0.973 and 0.977, registering a downward trend in general. The medical service demand at the township level is price inelastic, indicating that it is a necessity for rural residents. The downward trend of income elasticity under the influence of some health policies illustrates a lightening in economic burden for medical service demand among rural residents in township health clinics.

  7. Siblings versus parents and friends: longitudinal linkages to adolescent externalizing problems.

    Science.gov (United States)

    Defoe, Ivy N; Keijsers, Loes; Hawk, Skyler T; Branje, Susan; Dubas, Judith Semon; Buist, Kirsten; Frijns, Tom; van Aken, Marcel A G; Koot, Hans M; van Lier, Pol A C; Meeus, Wim

    2013-08-01

    It is well documented that friends' externalizing problems and negative parent-child interactions predict externalizing problems in adolescence, but relatively little is known about the role of siblings. This four-wave, multi-informant study investigated linkages of siblings' externalizing problems and sibling-adolescent negative interactions on adolescents' externalizing problems, while examining and controlling for similar linkages with friends and parents. Questionnaire data on externalizing problems and negative interactions were annually collected from 497 Dutch adolescents (M = 13.03 years, SD = 0.52, at baseline), as well as their siblings, mothers, fathers, and friends. Cross-lagged panel analyses revealed modest unique longitudinal paths from sibling externalizing problems to adolescent externalizing problems, for male and female adolescents, and for same-sex and mixed-sex sibling dyads, but only from older to younger siblings. Moreover, these paths were above and beyond significant paths from mother-adolescent negative interaction and friend externalizing problems to adolescent externalizing problems, 1 year later. No cross-lagged paths existed between sibling-adolescent negative interaction and adolescent externalizing problems. Taken together, it appears that especially older sibling externalizing problems may be a unique social risk factor for adolescent externalizing problems, equal in strength to significant parents' and friends' risk factors. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.

  8. An exploratory study to examine intentions to adopt an evidence-based HIV linkage-to-care intervention among state health department AIDS directors in the United States

    Directory of Open Access Journals (Sweden)

    Norton Wynne E

    2012-04-01

    Full Text Available Abstract Background Widespread dissemination and implementation of evidence-based human immunodeficiency virus (HIV linkage-to-care (LTC interventions is essential for improving HIV-positive patients' health outcomes and reducing transmission to uninfected others. To date, however, little work has focused on identifying factors associated with intentions to adopt LTC interventions among policy makers, including city, state, and territory health department AIDS directors who play a critical role in deciding whether an intervention is endorsed, distributed, and/or funded throughout their region. Methods Between December 2010 and February 2011, we administered an online questionnaire with state, territory, and city health department AIDS directors throughout the United States to identify factors associated with intentions to adopt an LTC intervention. Guided by pertinent theoretical frameworks, including the Diffusion of Innovations and the "push-pull" capacity model, we assessed participants' attitudes towards the intervention, perceived organizational and contextual demand and support for the intervention, likelihood of adoption given endorsement from stakeholder groups (e.g., academic researchers, federal agencies, activist organizations, and likelihood of enabling future dissemination efforts by recommending the intervention to other health departments and community-based organizations. Results Forty-four participants (67% of the eligible sample completed the online questionnaire. Approximately one-third (34.9% reported that they intended to adopt the LTC intervention for use in their city, state, or territory in the future. Consistent with prior, related work, these participants were classified as LTC intervention "adopters" and were compared to "nonadopters" for data analysis. Overall, adopters reported more positive attitudes and greater perceived demand and support for the intervention than did nonadopters. Further, participants varied with

  9. Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Vedanthan, Rajesh; Kamano, Jemima H; Naanyu, Violet; Delong, Allison K; Were, Martin C; Finkelstein, Eric A; Menya, Diana; Akwanalo, Constantine O; Bloomfield, Gerald S; Binanay, Cynthia A; Velazquez, Eric J; Hogan, Joseph W; Horowitz, Carol R; Inui, Thomas S; Kimaiyo, Sylvester; Fuster, Valentin

    2014-04-27

    Hypertension is the leading global risk factor for mortality. Hypertension treatment and control rates are low worldwide, and delays in seeking care are associated with increased mortality. Thus, a critical component of hypertension management is to optimize linkage and retention to care. This study investigates whether community health workers, equipped with a tailored behavioral communication strategy and smartphone technology, can increase linkage and retention of hypertensive individuals to a hypertension care program and significantly reduce blood pressure among them. The study will be conducted in the Kosirai and Turbo Divisions of western Kenya. An initial phase of qualitative inquiry will assess facilitators and barriers of linkage and retention to care using a modified Health Belief Model as a conceptual framework. Subsequently, we will conduct a cluster randomized controlled trial with three arms: 1) usual care (community health workers with the standard level of hypertension care training); 2) community health workers with an additional tailored behavioral communication strategy; and 3) community health workers with a tailored behavioral communication strategy who are also equipped with smartphone technology. The co-primary outcome measures are: 1) linkage to hypertension care, and 2) one-year change in systolic blood pressure among hypertensive individuals. Cost-effectiveness analysis will be conducted in terms of costs per unit decrease in blood pressure and costs per disability-adjusted life year gained. This study will provide evidence regarding the effectiveness and cost-effectiveness of strategies to optimize linkage and retention to hypertension care that can be applicable to non-communicable disease management in low- and middle-income countries. This trial is registered with (NCT01844596) on 30 April 2013.

  10. Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees

    Science.gov (United States)

    Moser, Kathy L.; Neas, Barbara R.; Salmon, Jane E.; Yu, Hua; Gray-McGuire, Courtney; Asundi, Neeraj; Bruner, Gail R.; Fox, Jerome; Kelly, Jennifer; Henshall, Stephanie; Bacino, Debra; Dietz, Myron; Hogue, Robert; Koelsch, Gerald; Nightingale, Lydia; Shaver, Tim; Abdou, Nabih I.; Albert, Daniel A.; Carson, Craig; Petri, Michelle; Treadwell, Edward L.; James, Judith A.; Harley, John B.

    1998-01-01

    Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by production of autoantibodies against intracellular antigens including DNA, ribosomal P, Ro (SS-A), La (SS-B), and the spliceosome. Etiology is suspected to involve genetic and environmental factors. Evidence of genetic involvement includes: associations with HLA-DR3, HLA-DR2, Fcγ receptors (FcγR) IIA and IIIA, and hereditary complement component deficiencies, as well as familial aggregation, monozygotic twin concordance >20%, λs > 10, purported linkage at 1q41–42, and inbred mouse strains that consistently develop lupus. We have completed a genome scan in 94 extended multiplex pedigrees by using model-based linkage analysis. Potential [log10 of the odds for linkage (lod) > 2.0] SLE loci have been identified at chromosomes 1q41, 1q23, and 11q14–23 in African-Americans; 14q11, 4p15, 11q25, 2q32, 19q13, 6q26–27, and 12p12–11 in European-Americans; and 1q23, 13q32, 20q13, and 1q31 in all pedigrees combined. An effect for the FcγRIIA candidate polymorphism) at 1q23 (lod = 3.37 in African-Americans) is syntenic with linkage in a murine model of lupus. Sib-pair and multipoint nonparametric analyses also support linkage (P 2.0). Our results are consistent with the presumed complexity of genetic susceptibility to SLE and illustrate racial origin is likely to influence the specific nature of these genetic effects. PMID:9843982

  11. Testing the sensitivity of trade linkages in Europe to compound drought events

    Science.gov (United States)

    Veldkamp, Ted; Koks, Elco; Thissen, Mark; Wahl, Thomas; Haigh, Ivan; Muis, Sanne; Ward, Philip

    2017-04-01

    Droughts can be defined as spatially extensive events that are characterized by temporal deficits in precipitation, soil moisture or streamflow, and have the potential to cause large direct and indirect economic losses. Many European countries face drought as an economically important hazard, with agriculture, livestock, forestry, energy, industry, and water sectors particularly at risk, causing economic losses of 139 billion US over the past 30 years. Apart from these direct impacts, business production and the flow of goods and services can be affected indirectly by droughts. With consequences that can propagate through the economic system affecting regions not directly hit by the drought event itself, or in time-periods long after the original drought event occurred. In this study, we evaluate the sensitivity of existing trade linkages between the different NUTS-2 regions in Europe to the coupled occurrence of hydro-meteorological drought events, and their associated production losses. Using a multi-regional supply-use model for Europe, we have, on a product level, insight in the existing trade linkages between NUTS-2 regions. Using this information in combination with historical drought data, we assessed and identified for a selection of water related products: 1) the dependency-structures of the NUTS-2 regions within Europe for the import and export of products (and therein water); 2) the coupled nature of drought events occurring in regions that are linked via these trade-patterns; 3) the probability of not meeting demands (on a product level) due to drought events and the associated (indirect economic) impacts; and 4) regions that lose or benefit from their selection of trade-partners given the coupled nature of drought events, as well as the net effects for Europe as a whole.

  12. Raising cane: linkages, organizations and negotiations in Malang's sugar industry, East Java.

    NARCIS (Netherlands)

    Hartveld, A.J.

    1996-01-01

    The linkages between the Javanese sugar industry and the village communities have drawn the attention of both historians and social scientists. The formal organization of these linkages has changed drastically since Indonesia's independence; from plantation into outgrowers production contract system

  13. Nickel-catalyzed proton-deuterium exchange (HDX) procedures for glycosidic linkage analysis of complex carbohydrates

    Science.gov (United States)

    The structural analysis of complex carbohydrates typically requires the assignment of three parameters: monosaccharide composition, the position of glycosidic linkages between monosaccharides, and the position and nature of non-carbohydrate substituents. The glycosidic linkage positions are often de...

  14. Document Fine Scale Linkage Areas and Conservation Delivery of the Northern Rockies in US and Canada

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Assessment of fine-scale habitat linkages in the Northern Rockies through use of biological DNA, telemetry and ecological modeling to predict critical linkages for...

  15. Autonomous Hybrid Priority Queueing for Scheduling Residential Energy Demands

    Science.gov (United States)

    Kalimullah, I. Q.; Shamroukh, M.; Sahar, N.; Shetty, S.

    2017-05-01

    The advent of smart grid technologies has opened up opportunities to manage the energy consumption of the users within a residential smart grid system. Demand response management is particularly being employed to reduce the overall load on an electricity network which could in turn reduce outages and electricity costs. The objective of this paper is to develop an intelligible scheduler to optimize the energy available to a micro grid through hybrid queueing algorithm centered around the consumers’ energy demands. This is achieved by shifting certain schedulable load appliances to light load hours. Various factors such as the type of demand, grid load, consumers’ energy usage patterns and preferences are considered while formulating the logical constraints required for the algorithm. The algorithm thus obtained is then implemented in MATLAB workspace to simulate its execution by an Energy Consumption Scheduler (ECS) found within smart meters, which automatically finds the optimal energy consumption schedule tailor made to fit each consumer within the micro grid network.

  16. Development of fitness screening protocols for physically demanding occupations.

    Science.gov (United States)

    Jamnik, V K; Gledhill, N

    1992-09-01

    The fitness screening of applications to physically demand occupations has become increasingly complex with the advent of Equal Opportunity legislation and Affirmative Action initiatives. A comprehensive study was conducted of the physical demands and associated physiological responses of workers in strenuous jobs at a large multifaceted natural gas company. Based on these findings, an applicant fitness screening protocol was developed and validated. The protocol was implemented for an 18-month period, after which the results were examined with regard to gender differences in success rates and other influencing factors. Because of ongoing changes in attitudes and practices in the workplace, fitness screening for applicants was interrupted and a review was initiated of all strenuous jobs with the aim of reducing their physical demands.

  17. The job demands-resources model of burnout.

    Science.gov (United States)

    Demerouti, E; Bakker, A B; Nachreiner, F; Schaufeli, W B

    2001-06-01

    The job demands-resources (JD-R) model proposes that working conditions can be categorized into 2 broad categories, job demands and job resources. that are differentially related to specific outcomes. A series of LISREL analyses using self-reports as well as observer ratings of the working conditions provided strong evidence for the JD-R model: Job demands are primarily related to the exhaustion component of burnout, whereas (lack of) job resources are primarily related to disengagement. Highly similar patterns were observed in each of 3 occupational groups: human services, industry, and transport (total N = 374). In addition, results confirmed the 2-factor structure (exhaustion and disengagement) of a new burnout instrument--the Oldenburg Burnout Inventory--and suggested that this structure is essentially invariant across occupational groups.

  18. Multivariate Stable Isotope Analysis to Determine Linkages between Benzocaine Seizures

    Science.gov (United States)

    Kemp, H. F.; Meier-Augenstein, W.; Collins, M.; Salouros, H.; Cunningham, A.; Harrison, M.

    2012-04-01

    In July 2010, a woman was jailed for nine years in the UK after the prosecution successfully argued that attempting to import a cutting agent was proof of involvement in a conspiracy to supply Cocaine. That landmark ruling provided law enforcement agencies with much greater scope to tackle those involved in this aspect of the drug trade, specifically targeting those importing the likes of benzocaine or lidocaine. Huge quantities of these compounds are imported into the UK and between May and August 2010, four shipments of Benzocaine amounting to more then 4 tons had been seized as part of Operation Kitley, a joint initiative between the UK Border Agency and the Serious Organised Crime Agency (SOCA). By diluting cocaine, traffickers can make it go a lot further for very little cost, leading to huge profits. In recent years, dealers have moved away from inert substances, like sugar and baby milk powder, in favour of active pharmaceutical ingredients (APIs), including anaesthetics like Benzocaine and Lidocaine. Both these mimic the numbing effect of cocaine, and resemble it closely in colour, texture and some chemical behaviours, making it easier to conceal the fact that the drug has been diluted. API cutting agents have helped traffickers to maintain steady supplies in the face of successful interdiction and even expand the market in the UK, particularly to young people aged from their mid teens to early twenties. From importation to street-level, the purity of the drug can be reduced up to a factor of 80 and street level cocaine can have a cocaine content as low as 1%. In view of the increasing use of Benzocaine as cutting agent for Cocaine, a study was carried out to investigate if 2H, 13C, 15N and 18O stable isotope signatures could be used in conjunction with multivariate chemometric data analysis to determine potential linkage between benzocaine exhibits seized from different locations or individuals to assist with investigation and prosecution of drug

  19. Visualisation turns down energy demand

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Ole Michael [Danish Building and Urban Research, Hoersholm (Denmark)

    2003-07-01

    After many energy saving campaigns, Danish families give the impression that they are conscious of energy consumption. Children have learned to turn off the light and adults to buy low-energy bulbs and household appliances. Questioned about their energy consumption and its fluctuations, the same people nevertheless confess to not really knowing. You pay your energy bill but pay no attention to the current consumption, or its level. Unlike other types of consumption, energy consumption is an almost invisible type of consumption. Nevertheless, as a secondary consumption it is much affected by primary consumption in the form of white goods, appliances, cars, food etc., the main purpose of which usually is visibility. This paper presents the result of an experiment to make the energy consumption visible. Meters in the flats showing actual electricity, heat and water consumption confront tenants with the consequences of their own behaviour. The experiment also investigates different set-ups concerning information and communication about energy consumption. Monthly consumption and levels of consumption compared within the neighbourhood are elements of this information. Also quarterly eco-accounting, with key-figures of consumption and environmental considerations like CO{sub 2} emission, are part of the information set-up. Within the first year of visualisation one case shows a 9% reduction of heat and a 22% reduction of electricity. The other cases seem to follow the same tendency. The philosophy of the experiment is that you must know your position in order to change it. You must know about the level of your own energy consumption in order to turn down energy demand. The visible meters are elements in 'Urban Ecological Renewal of a Housing Block' (Hedebygade Block) in a central district of Copenhagen.

  20. Detection of QTL for Carcass Quality on Chromosome 6 by Exploiting Linkage and Linkage Disequilibrium in Hanwoo

    Directory of Open Access Journals (Sweden)

    J.-H. Lee

    2012-01-01

    Full Text Available The purpose of this study was to improve mapping power and resolution for the QTL influencing carcass quality in Hanwoo, which was previously detected on the bovine chromosome (BTA 6. A sample of 427 steers were chosen, which were the progeny from 45 Korean proven sires in the Hanwoo Improvement Center, Seosan, Korea. The samples were genotyped with the set of 2,535 SNPs on BTA6 that were imbedded in the Illumina bovine 50 k chip. A linkage disequilibrium variance component mapping (LDVCM method, which exploited both linkage between sires and their steers and population-wide linkage disequilibrium, was applied to detect QTL for four carcass quality traits. Fifteen QTL were detected at 0.1% comparison-wise level, for which five, three, five, and two QTL were associated with carcass weight (CWT, backfat thickness (BFT, longissimus dorsi muscle area (LMA, and marbling score (Marb, respectively. The number of QTL was greater compared with our previous results, in which twelve QTL for carcass quality were detected on the BTA6 in the same population by applying other linkage disequilibrium mapping approaches. One QTL for LMA was detected on the distal region (110,285,672 to 110,633,096 bp with the most significant evidence for linkage (p<10−5. Another QTL that was detected on the proximal region (33,596,515 to 33,897,434 bp was pleiotrophic, i.e. influencing CWT, BFT, and LMA. Our results suggest that the LDVCM is a good alternative method for QTL fine-mapping in detection and characterization of QTL.