WorldWideScience

Sample records for facility end-to-end beamline

  1. End to End Travel

    Data.gov (United States)

    US Agency for International Development — E2 Solutions is a web based end-to-end travel management tool that includes paperless travel authorization and voucher document submissions, document approval...

  2. CASTOR end-to-end monitoring

    International Nuclear Information System (INIS)

    Rekatsinas, Theodoros; Duellmann, Dirk; Pokorski, Witold; Ponce, Sebastien; Rabacal, Bartolomeu; Waldron, Dennis; Wojcieszuk, Jacek

    2010-01-01

    With the start of Large Hadron Collider approaching, storage and management of raw event data, as well as reconstruction and analysis data, is of crucial importance for the researchers. The CERN Advanced STORage system (CASTOR) is a hierarchical system developed at CERN, used to store physics production files and user files. CASTOR, as one of the essential software tools used by the LHC experiments, has to provide reliable services for storing and managing data. Monitoring of this complicated system is mandatory in order to assure its stable operation and improve its future performance. This paper presents the new monitoring system of CASTOR which provides operation and user request specific metrics. This system is build around a dedicated, optimized database schema. The schema is populated by PL/SQL procedures, which process a stream of incoming raw metadata from different CASTOR components, initially collected by the Distributed Logging Facility (DLF). A web interface has been developed for the visualization of the monitoring data. The different histograms and plots are created using PHP scripts which query the monitoring database.

  3. Moly99 Production Facility: Report on Beamline Components, Requirements, Costs

    Energy Technology Data Exchange (ETDEWEB)

    Bishofberger, Kip A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-23

    In FY14 we completed the design of the beam line for the linear accelerator production design concept. This design included a set of three bending magnets, quadrupole focusing magnets, and octopoles to flatten the beam on target. This design was generic and applicable to multiple different accelerators if necessary. In FY15 we built on that work to create specifications for the individual beam optic elements, including power supply requirements. This report captures the specification of beam line components with initial cost estimates for the NorthStar production facility.This report is organized as follows: The motivation of the beamline design is introduced briefly, along with renderings of the design. After that, a specific list is provided, which accounts for each beamline component, including part numbers and costs, to construct the beamline. After that, this report details the important sections of the beamline and individual components. A final summary and list of follow-on activities completes this report.

  4. Standardizing an End-to-end Accounting Service

    Science.gov (United States)

    Greenberg, Edward; Kazz, Greg

    2006-01-01

    Currently there are no space system standards available for space agencies to accomplish end-to-end accounting. Such a standard does not exist for spacecraft operations nor for tracing the relationship between the mission planning activities, the command sequences designed to perform those activities, the commands formulated to initiate those activities and the mission data and specifically the mission data products created by those activities. In order for space agencies to cross-support one another for data accountability/data tracing and for inter agency spacecraft to interoperate with each other, an international CCSDS standard for end-to-end data accountability/tracing needs to be developed. We will first describe the end-to-end accounting service model and functionality that supports the service. This model will describe how science plans that are ultimately transformed into commands can be associated with the telemetry products generated as a result of their execution. Moreover, the interaction between end-to-end accounting and service management will be explored. Finally, we will show how the standard end-to-end accounting service can be applied to a real life flight project i.e., the Mars Reconnaissance Orbiter project.

  5. OISI dynamic end-to-end modeling tool

    Science.gov (United States)

    Kersten, Michael; Weidler, Alexander; Wilhelm, Rainer; Johann, Ulrich A.; Szerdahelyi, Laszlo

    2000-07-01

    The OISI Dynamic end-to-end modeling tool is tailored to end-to-end modeling and dynamic simulation of Earth- and space-based actively controlled optical instruments such as e.g. optical stellar interferometers. `End-to-end modeling' is meant to denote the feature that the overall model comprises besides optical sub-models also structural, sensor, actuator, controller and disturbance sub-models influencing the optical transmission, so that the system- level instrument performance due to disturbances and active optics can be simulated. This tool has been developed to support performance analysis and prediction as well as control loop design and fine-tuning for OISI, Germany's preparatory program for optical/infrared spaceborne interferometry initiated in 1994 by Dornier Satellitensysteme GmbH in Friedrichshafen.

  6. End-to-End Security for Personal Telehealth

    NARCIS (Netherlands)

    Koster, R.P.; Asim, M.; Petkovic, M.

    2011-01-01

    Personal telehealth is in rapid development with innovative emerging applications like disease management. With personal telehealth people participate in their own care supported by an open distributed system with health services. This poses new end-to-end security and privacy challenges. In this

  7. Utilizing Domain Knowledge in End-to-End Audio Processing

    DEFF Research Database (Denmark)

    Tax, Tycho; Antich, Jose Luis Diez; Purwins, Hendrik

    2017-01-01

    to learn the commonly-used log-scaled mel-spectrogram transformation. Secondly, we demonstrate that upon initializing the first layers of an end-to-end CNN classifier with the learned transformation, convergence and performance on the ESC-50 environmental sound classification dataset are similar to a CNN......-based model trained on the highly pre-processed log-scaled mel-spectrogram features....

  8. Measurements and analysis of end-to-end Internet dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Paxson, Vern [Univ. of California, Berkeley, CA (United States). Computer Science Division

    1997-04-01

    Accurately characterizing end-to-end Internet dynamics - the performance that a user actually obtains from the lengthy series of network links that comprise a path through the Internet - is exceptionally difficult, due to the network`s immense heterogeneity. At the heart of this work is a `measurement framework` in which a number of sites around the Internet host a specialized measurement service. By coordinating `probes` between pairs of these sites one can measure end-to-end behavior along O(N2) paths for a framework consisting of N sites. Consequently, one obtains a superlinear scaling that allows measuring a rich cross-section of Internet behavior without requiring huge numbers of observation points. 37 sites participated in this study, allowing the author to measure more than 1,000 distinct Internet paths. The first part of this work looks at the behavior of end-to-end routing: the series of routers over which a connection`s packets travel. Based on 40,000 measurements made using this framework, the author analyzes: routing `pathologies` such as loops, outages, and flutter; the stability of routes over time; and the symmetry of routing along the two directions of an end-to-end path. The author finds that pathologies increased significantly over the course of 1995 and that Internet paths are heavily dominated by a single route. The second part of this work studies end-to-end Internet packet dynamics. The author analyzes 20,000 TCP transfers of 100 Kbyte each to investigate the performance of both the TCP endpoints and the Internet paths. The measurements used for this part of the study are much richer than those for the first part, but require a great degree of attention to issues of calibration, which are addressed by applying self-consistency checks to the measurements whenever possible. The author finds that packet filters are capable of a wide range of measurement errors, some of which, if undetected, can significantly taint subsequent analysis.

  9. End-to-End Operations in the ELT Era

    Science.gov (United States)

    Hainaut, O. R.; Bierwirth, T.; Brillant, S.; Mieske, S.; Patat, F.; Rejkuba, M.; Romaniello, M.; Sterzik, M.

    2018-03-01

    The Data Flow System is the infrastructure on which Very Large Telescope (VLT) observations are performed at the Observatory, before and after the observations themselves take place. Since its original conception in the late 1990s, it has evolved to accommodate new observing modes and new instruments on La Silla and Paranal. Several updates and upgrades are needed to overcome its obsolescence and to integrate requirements from the new instruments from the community and, of course, from ESO's Extremely Large Telescope (ELT), which will be integrated into Paranal's operations. We describe the end-to-end operations and the resulting roadmap guiding their further development.

  10. End-to-end plasma bubble PIC simulations on GPUs

    Science.gov (United States)

    Germaschewski, Kai; Fox, William; Matteucci, Jackson; Bhattacharjee, Amitava

    2017-10-01

    Accelerator technologies play a crucial role in eventually achieving exascale computing capabilities. The current and upcoming leadership machines at ORNL (Titan and Summit) employ Nvidia GPUs, which provide vast computational power but also need specifically adapted computational kernels to fully exploit them. In this work, we will show end-to-end particle-in-cell simulations of the formation, evolution and coalescence of laser-generated plasma bubbles. This work showcases the GPU capabilities of the PSC particle-in-cell code, which has been adapted for this problem to support particle injection, a heating operator and a collision operator on GPUs.

  11. Cyberinfrastructure for End-to-End Environmental Explorations

    Science.gov (United States)

    Merwade, V.; Kumar, S.; Song, C.; Zhao, L.; Govindaraju, R.; Niyogi, D.

    2007-12-01

    The design and implementation of a cyberinfrastructure for End-to-End Environmental Exploration (C4E4) is presented. The C4E4 framework addresses the need for an integrated data/computation platform for studying broad environmental impacts by combining heterogeneous data resources with state-of-the-art modeling and visualization tools. With Purdue being a TeraGrid Resource Provider, C4E4 builds on top of the Purdue TeraGrid data management system and Grid resources, and integrates them through a service-oriented workflow system. It allows researchers to construct environmental workflows for data discovery, access, transformation, modeling, and visualization. Using the C4E4 framework, we have implemented an end-to-end SWAT simulation and analysis workflow that connects our TeraGrid data and computation resources. It enables researchers to conduct comprehensive studies on the impact of land management practices in the St. Joseph watershed using data from various sources in hydrologic, atmospheric, agricultural, and other related disciplines.

  12. End-to-end tests using alanine dosimetry in scanned proton beams

    Science.gov (United States)

    Carlino, A.; Gouldstone, C.; Kragl, G.; Traneus, E.; Marrale, M.; Vatnitsky, S.; Stock, M.; Palmans, H.

    2018-03-01

    This paper describes end-to-end test procedures as the last fundamental step of medical commissioning before starting clinical operation of the MedAustron synchrotron-based pencil beam scanning (PBS) therapy facility with protons. One in-house homogeneous phantom and two anthropomorphic heterogeneous (head and pelvis) phantoms were used for end-to-end tests at MedAustron. The phantoms were equipped with alanine detectors, radiochromic films and ionization chambers. The correction for the ‘quenching’ effect of alanine pellets was implemented in the Monte Carlo platform of the evaluation version of RayStation TPS. During the end-to-end tests, the phantoms were transferred through the workflow like real patients to simulate the entire clinical workflow: immobilization, imaging, treatment planning and dose delivery. Different clinical scenarios of increasing complexity were simulated: delivery of a single beam, two oblique beams without and with range shifter. In addition to the dose comparison in the plastic phantoms the dose obtained from alanine pellet readings was compared with the dose determined with the Farmer ionization chamber in water. A consistent systematic deviation of about 2% was found between alanine dosimetry and the ionization chamber dosimetry in water and plastic materials. Acceptable agreement of planned and delivered doses was observed together with consistent and reproducible results of the end-to-end testing performed with different dosimetric techniques (alanine detectors, ionization chambers and EBT3 radiochromic films). The results confirmed the adequate implementation and integration of the new PBS technology at MedAustron. This work demonstrates that alanine pellets are suitable detectors for end-to-end tests in proton beam therapy and the developed procedures with customized anthropomorphic phantoms can be used to support implementation of PBS technology in clinical practice.

  13. An end to end secure CBIR over encrypted medical database.

    Science.gov (United States)

    Bellafqira, Reda; Coatrieux, Gouenou; Bouslimi, Dalel; Quellec, Gwenole

    2016-08-01

    In this paper, we propose a new secure content based image retrieval (SCBIR) system adapted to the cloud framework. This solution allows a physician to retrieve images of similar content within an outsourced and encrypted image database, without decrypting them. Contrarily to actual CBIR approaches in the encrypted domain, the originality of the proposed scheme stands on the fact that the features extracted from the encrypted images are themselves encrypted. This is achieved by means of homomorphic encryption and two non-colluding servers, we however both consider as honest but curious. In that way an end to end secure CBIR process is ensured. Experimental results carried out on a diabetic retinopathy database encrypted with the Paillier cryptosystem indicate that our SCBIR achieves retrieval performance as good as if images were processed in their non-encrypted form.

  14. System of end-to-end symmetric database encryption

    Science.gov (United States)

    Galushka, V. V.; Aydinyan, A. R.; Tsvetkova, O. L.; Fathi, V. A.; Fathi, D. V.

    2018-05-01

    The article is devoted to the actual problem of protecting databases from information leakage, which is performed while bypassing access control mechanisms. To solve this problem, it is proposed to use end-to-end data encryption, implemented at the end nodes of an interaction of the information system components using one of the symmetric cryptographic algorithms. For this purpose, a key management method designed for use in a multi-user system based on the distributed key representation model, part of which is stored in the database, and the other part is obtained by converting the user's password, has been developed and described. In this case, the key is calculated immediately before the cryptographic transformations and is not stored in the memory after the completion of these transformations. Algorithms for registering and authorizing a user, as well as changing his password, have been described, and the methods for calculating parts of a key when performing these operations have been provided.

  15. End-to-end learning for digital hologram reconstruction

    Science.gov (United States)

    Xu, Zhimin; Zuo, Si; Lam, Edmund Y.

    2018-02-01

    Digital holography is a well-known method to perform three-dimensional imaging by recording the light wavefront information originating from the object. Not only the intensity, but also the phase distribution of the wavefront can then be computed from the recorded hologram in the numerical reconstruction process. However, the reconstructions via the traditional methods suffer from various artifacts caused by twin-image, zero-order term, and noise from image sensors. Here we demonstrate that an end-to-end deep neural network (DNN) can learn to perform both intensity and phase recovery directly from an intensity-only hologram. We experimentally show that the artifacts can be effectively suppressed. Meanwhile, our network doesn't need any preprocessing for initialization, and is comparably fast to train and test, in comparison with the recently published learning-based method. In addition, we validate that the performance improvement can be achieved by introducing a prior on sparsity.

  16. End-to-End Adversarial Retinal Image Synthesis.

    Science.gov (United States)

    Costa, Pedro; Galdran, Adrian; Meyer, Maria Ines; Niemeijer, Meindert; Abramoff, Michael; Mendonca, Ana Maria; Campilho, Aurelio

    2018-03-01

    In medical image analysis applications, the availability of the large amounts of annotated data is becoming increasingly critical. However, annotated medical data is often scarce and costly to obtain. In this paper, we address the problem of synthesizing retinal color images by applying recent techniques based on adversarial learning. In this setting, a generative model is trained to maximize a loss function provided by a second model attempting to classify its output into real or synthetic. In particular, we propose to implement an adversarial autoencoder for the task of retinal vessel network synthesis. We use the generated vessel trees as an intermediate stage for the generation of color retinal images, which is accomplished with a generative adversarial network. Both models require the optimization of almost everywhere differentiable loss functions, which allows us to train them jointly. The resulting model offers an end-to-end retinal image synthesis system capable of generating as many retinal images as the user requires, with their corresponding vessel networks, by sampling from a simple probability distribution that we impose to the associated latent space. We show that the learned latent space contains a well-defined semantic structure, implying that we can perform calculations in the space of retinal images, e.g., smoothly interpolating new data points between two retinal images. Visual and quantitative results demonstrate that the synthesized images are substantially different from those in the training set, while being also anatomically consistent and displaying a reasonable visual quality.

  17. Safety Analysis Report: X17B2 beamline Synchrotron Medical Research Facility

    International Nuclear Information System (INIS)

    Gmuer, N.F.; Thomlinson, W.

    1990-02-01

    This report contains a safety analysis for the X17B2 beamline synchrotron medical research facility. Health hazards, risk assessment and building systems are discussed. Reference is made to transvenous coronary angiography

  18. Long-pulse beamlines for the mirror fusion test facility

    International Nuclear Information System (INIS)

    Stone, R.R.; Goldner, A.I.; Poulsen, P.

    1984-01-01

    We have recently obtained test results indicating that a beam of pure full-energy deuterium particles can be delivered to the plasma targets in MFTF-B. We used a close-coupled separator magnet with the ion source to separate the impurities from the full-energy deuterium particles. Our completed studies show that the usual iron-core sweep magnet and shielding used in neutral beamlines can be eliminated and the gas flow out of the beamline decreased. This design also reduces beam losses. We will use smooth-bore OFHC tube arrays brazed to manifolds for the active heat transfer surfaces. Tests indicate that both burnout and life requirements are met by this design. In this paper, we present test results and discuss the MFTF-B long-pulse beamline configuration

  19. A Bayes Theory-Based Modeling Algorithm to End-to-end Network Traffic

    OpenAIRE

    Zhao Hong-hao; Meng Fan-bo; Zhao Si-wen; Zhao Si-hang; Lu Yi

    2016-01-01

    Recently, network traffic has exponentially increasing due to all kind of applications, such as mobile Internet, smart cities, smart transportations, Internet of things, and so on. the end-to-end network traffic becomes more important for traffic engineering. Usually end-to-end traffic estimation is highly difficult. This paper proposes a Bayes theory-based method to model the end-to-end network traffic. Firstly, the end-to-end network traffic is described as a independent identically distrib...

  20. The actinide beamline - A new AMS facility at ANTARES

    International Nuclear Information System (INIS)

    Hotchkis, M.A.C.; Lee, P.J.; Mino, N.

    1998-01-01

    At the ANTARES accelerator a new beamline has been commissioned, incorporating new magnetic and electrostatic analysers, to optimise the efficiency for Actinides detection by Accelerator Mass Spectrometry. The detection of Actinides, particularly the isotopic ratios of uranium and plutonium, provide unique signatures for nuclear safeguards purposes. We are currently engaged in a project to evaluate the application of AMS to the measurement of Actinides in environmental samples for nuclear safeguards. Measurement of 236 U is of particular interest as a means of tracing the anthropogenic component of uranium. 236 U is expected to be present in natural samples at an extremely low level ( 236 U: 238 U ratio ∼10 -10 ). It has recently been demonstrated that AMS has sufficient sensitivity to detect 236 U at this level. The principal components of the new beamline include: an electrostatic quadrupole, a 12 deg electrostatic deflector, a 90 deg electrostatic analyser, a multi-isotope detection system including ion counters and Faraday cups. The beamline was completed in September 1998 and initial tests have been performed with iodine samples

  1. Status of the ELIMED Beamline at the ELIMAIA facility

    Czech Academy of Sciences Publication Activity Database

    Schillaci, F.; Cirrone, G.A.P.; Cuttone, G.; Romano, F.; Scuderi, Valentina; Allegra, L.; Amato, A.; Andó, L.; Costa, M.; Gallo, G.; Leanza, R.; Maggiore, M.; Milluzzo, G.; Petringa, G.; Pipek, J.; Russo, A.D.; Korn, Georg; Margarone, Daniele; Leray, M.J.; Tasset-Maye, O.; Antoine, S.; Jehanno, P.

    2016-01-01

    Roč. 11, Dec (2016), 1-5, č. článku C12052. ISSN 1748-0221 R&D Projects: GA MŠk EF15_008/0000162; GA MŠk LQ1606 Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162 Institutional support: RVO:68378271 Keywords : accelerator subsystems and technologies * accelerator applications * beam dynamics * beam optics Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 1.220, year: 2016

  2. Dedicated Beamline Facilities for Catalytic Research. Synchrotron Catalysis Consortium (SCC)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jingguang [Columbia Univ., New York, NY; Frenkel, Anatoly [Yeshiva Univ., New York, NY (United States); Rodriguez, Jose [Brookhaven National Lab. (BNL), Upton, NY (United States); Adzic, Radoslav [Brookhaven National Lab. (BNL), Upton, NY (United States); Bare, Simon R. [UOP LLC, Des Plaines, IL (United States); Hulbert, Steve L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Karim, Ayman [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mullins, David R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Overbury, Steve [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-03-04

    Synchrotron spectroscopies offer unique advantages over conventional techniques, including higher detection sensitivity and molecular specificity, faster detection rate, and more in-depth information regarding the structural, electronic and catalytic properties under in-situ reaction conditions. Despite these advantages, synchrotron techniques are often underutilized or unexplored by the catalysis community due to various perceived and real barriers, which will be addressed in the current proposal. Since its establishment in 2005, the Synchrotron Catalysis Consortium (SCC) has coordinated significant efforts to promote the utilization of cutting-edge catalytic research under in-situ conditions. The purpose of the current renewal proposal is aimed to provide assistance, and to develop new sciences/techniques, for the catalysis community through the following concerted efforts: Coordinating the implementation of a suite of beamlines for catalysis studies at the new NSLS-II synchrotron source; Providing assistance and coordination for catalysis users at an SSRL catalysis beamline during the initial period of NSLS to NSLS II transition; Designing in-situ reactors for a variety of catalytic and electrocatalytic studies; Assisting experimental set-up and data analysis by a dedicated research scientist; Offering training courses and help sessions by the PIs and co-PIs.

  3. AN ANALYSIS OF THE APPLICATION END TO END QUALITY OF SERVICE ON 3G TELECOMMUNICATION NETWORK

    Directory of Open Access Journals (Sweden)

    Cahya Lukito

    2012-05-01

    Full Text Available End to End Quality of Service is a way to provide data package service in a telecommunication network that based on Right Price, Right Service Level, and Right Quality. The goal of this research is to analyze the impact of End to End QoS use on 3G telecommunication network for voice service and data. This research uses an analysis method by doing the application on the lab. The result that is achieved in this research shows that End to End QoS is very influental to the Service Level Agreement to the users of the telecommunication service.Keywords: End to End Qos, SLA, Diffserv

  4. The status of the first infrared beamline at Shanghai Synchrotron Radiation Facility

    International Nuclear Information System (INIS)

    Ji, Te; Tong, Yajun; Zhu, Huachun; Zhang, Zengyan; Peng, Weiwei; Chen, Min; Xiao, Tiqiao; Xu, Hongjie

    2015-01-01

    Construction of the first infrared beamline BL01B1 at Shanghai Synchrotron Radiation Facility (SSRF) was completed at the end of 2013. The IR beamline collects both edge radiation (ER) and bending magnet radiation (BMR) from a port, providing a solid angle of 40 mrad and 20 mrad in the horizontal and vertical directions, respectively. The optical layout of the infrared beamline and the design of the extraction mirror are described in this paper. A calculation of the beam propagation has been used to optimize the parameters of the optical components. The photon flux and spatial resolution have been measured at the end-station, and the experimental results are in good agreement with the theoretical calculation

  5. The status of the first infrared beamline at Shanghai Synchrotron Radiation Facility

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Te; Tong, Yajun; Zhu, Huachun; Zhang, Zengyan; Peng, Weiwei; Chen, Min, E-mail: chenmin@sinap.ac.cn; Xiao, Tiqiao; Xu, Hongjie

    2015-07-11

    Construction of the first infrared beamline BL01B1 at Shanghai Synchrotron Radiation Facility (SSRF) was completed at the end of 2013. The IR beamline collects both edge radiation (ER) and bending magnet radiation (BMR) from a port, providing a solid angle of 40 mrad and 20 mrad in the horizontal and vertical directions, respectively. The optical layout of the infrared beamline and the design of the extraction mirror are described in this paper. A calculation of the beam propagation has been used to optimize the parameters of the optical components. The photon flux and spatial resolution have been measured at the end-station, and the experimental results are in good agreement with the theoretical calculation.

  6. The status of the first infrared beamline at Shanghai Synchrotron Radiation Facility

    Science.gov (United States)

    Ji, Te; Tong, Yajun; Zhu, Huachun; Zhang, Zengyan; Peng, Weiwei; Chen, Min; Xiao, Tiqiao; Xu, Hongjie

    2015-07-01

    Construction of the first infrared beamline BL01B1 at Shanghai Synchrotron Radiation Facility (SSRF) was completed at the end of 2013. The IR beamline collects both edge radiation (ER) and bending magnet radiation (BMR) from a port, providing a solid angle of 40 mrad and 20 mrad in the horizontal and vertical directions, respectively. The optical layout of the infrared beamline and the design of the extraction mirror are described in this paper. A calculation of the beam propagation has been used to optimize the parameters of the optical components. The photon flux and spatial resolution have been measured at the end-station, and the experimental results are in good agreement with the theoretical calculation.

  7. Experimental demonstration of software defined data center optical networks with Tbps end-to-end tunability

    Science.gov (United States)

    Zhao, Yongli; Zhang, Jie; Ji, Yuefeng; Li, Hui; Wang, Huitao; Ge, Chao

    2015-10-01

    The end-to-end tunability is important to provision elastic channel for the burst traffic of data center optical networks. Then, how to complete the end-to-end tunability based on elastic optical networks? Software defined networking (SDN) based end-to-end tunability solution is proposed for software defined data center optical networks, and the protocol extension and implementation procedure are designed accordingly. For the first time, the flexible grid all optical networks with Tbps end-to-end tunable transport and switch system have been online demonstrated for data center interconnection, which are controlled by OpenDayLight (ODL) based controller. The performance of the end-to-end tunable transport and switch system has been evaluated with wavelength number tuning, bit rate tuning, and transmit power tuning procedure.

  8. A Bayes Theory-Based Modeling Algorithm to End-to-end Network Traffic

    Directory of Open Access Journals (Sweden)

    Zhao Hong-hao

    2016-01-01

    Full Text Available Recently, network traffic has exponentially increasing due to all kind of applications, such as mobile Internet, smart cities, smart transportations, Internet of things, and so on. the end-to-end network traffic becomes more important for traffic engineering. Usually end-to-end traffic estimation is highly difficult. This paper proposes a Bayes theory-based method to model the end-to-end network traffic. Firstly, the end-to-end network traffic is described as a independent identically distributed normal process. Then the Bases theory is used to characterize the end-to-end network traffic. By calculating the parameters, the model is determined correctly. Simulation results show that our approach is feasible and effective.

  9. Highlights from e-EPS: New milestone for ELI Beamlines facility

    CERN Multimedia

    Jorge Rivero González, e-EPS News

    2013-01-01

    e-EPS News is a monthly addition to the CERN Bulletin line-up, showcasing articles from e-EPS – the European Physical Society newsletter – as part of a collaboration between the two publications.   On 16 September 2013, the Extreme Light Infrastructure (ELI) Beamlines facility awarded a contract worth approximately €34.5m to Lawrence Livermore National Security LLC (LLNS, California, USA) to develop and deliver a state-of-the-art laser system that will be at the heart of the ELI Beamlines user facility. Located in the village of Dolní Břežany, Czech Republic, the ELI Beamlines facility aims to pioneer work in a number of research fields using ultra-high intensity lasers. The facility will host a cutting-edge research laser, around 100 times more powerful than any other laser in operation today. In particular, it will focus on providing users with ultra-short energetic particle beams (10 GeV) and radiation beams (up to a few MeV), produced by...

  10. A beamline systems model for Accelerator-Driven Transmutation Technology (ADTT) facilities

    Energy Technology Data Exchange (ETDEWEB)

    Todd, A.M.M.; Paulson, C.C.; Peacock, M.A. [Grumman Research and Development Center, Princeton, NJ (United States)] [and others

    1995-10-01

    A beamline systems code, that is being developed for Accelerator-Driven Transmutation Technology (ADTT) facility trade studies, is described. The overall program is a joint Grumman, G.H. Gillespie Associates (GHGA) and Los Alamos National Laboratory effort. The GHGA Accelerator Systems Model (ASM) has been adopted as the framework on which this effort is based. Relevant accelerator and beam transport models from earlier Grumman systems codes are being adapted to this framework. Preliminary physics and engineering models for each ADTT beamline component have been constructed. Examples noted include a Bridge Coupled Drift Tube Linac (BCDTL) and the accelerator thermal system. A decision has been made to confine the ASM framework principally to beamline modeling, while detailed target/blanket, balance-of-plant and facility costing analysis will be performed externally. An interfacing external balance-of-plant and facility costing model, which will permit the performance of iterative facility trade studies, is under separate development. An ABC (Accelerator Based Conversion) example is used to highlight the present models and capabilities.

  11. A beamline systems model for Accelerator-Driven Transmutation Technology (ADTT) facilities

    International Nuclear Information System (INIS)

    Todd, Alan M. M.; Paulson, C. C.; Peacock, M. A.; Reusch, M. F.

    1995-01-01

    A beamline systems code, that is being developed for Accelerator-Driven Transmutation Technology (ADTT) facility trade studies, is described. The overall program is a joint Grumman, G. H. Gillespie Associates (GHGA) and Los Alamos National Laboratory effort. The GHGA Accelerator Systems Model (ASM) has been adopted as the framework on which this effort is based. Relevant accelerator and beam transport models from earlier Grumman systems codes are being adapted to this framework. Preliminary physics and engineering models for each ADTT beamline component have been constructed. Examples noted include a Bridge Coupled Drift Tube Linac (BCDTL) and the accelerator thermal system. A decision has been made to confine the ASM framework principally to beamline modeling, while detailed target/blanket, balance-of-plant and facility costing analysis will be performed externally. An interfacing external balance-of-plant and facility costing model, which will permit the performance of iterative facility trade studies, is under separate development. An ABC (Accelerator Based Conversion) example is used to highlight the present models and capabilities

  12. Pulse generation and preamplification for long pulse beamlines of Orion laser facility.

    Science.gov (United States)

    Hillier, David I; Winter, David N; Hopps, Nicholas W

    2010-06-01

    We describe the pulse generation, shaping, and preamplification system for the nanosecond beamlines of the Orion laser facility. The system generates shaped laser pulses of up to approximately 1 J of 100 ps-5 ns duration with a programmable temporal profile. The laser has a 30th-power supergaussian spatial profile and is diffraction limited. The system is capable of imposing 2D smoothing by spectral dispersion upon the beam, which will produce a nonuniformity of 10% rms at the target.

  13. The ANL X6B beamline at NSLS: A versatile facility

    International Nuclear Information System (INIS)

    Huang, K.G.; Ramanathan, M.; Montano, P.A.; Illinois Univ., Chicago, IL

    1994-07-01

    We have described the x-ray optics and beamline performance of the ANL X6B beam line at the NSLS. Considerable flexibility has been built into the beam line to accommodate a wide range of x-ray diffraction, scattering, and spectroscopy experiments with various requirements. We presented selected examples of experimental results and showed that with the high intensity, high energy resolution, high-q resolution, and energy tunability, the X6B beam line has become a versatile facility

  14. Model outputs - Developing end-to-end models of the Gulf of California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the northern Gulf of California, linking oceanography, biogeochemistry, food web...

  15. Physical oceanography - Developing end-to-end models of the California Current Large Marine Ecosystem

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the California Current LME, linking oceanography, biogeochemistry, food web...

  16. Atlantis model outputs - Developing end-to-end models of the California Current Large Marine Ecosystem

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the California Current LME, linking oceanography, biogeochemistry, food web...

  17. Gas delivery system and beamline studies for the test beam facility of the Collider Detector at Fermilab

    International Nuclear Information System (INIS)

    Franke, H.G. III.

    1987-12-01

    A fixed-target test beam facility has been designed and constructed at the Meson Test (MT) site to support studies of components of the Collider Detector at Fermi National Accelerator Laboratory (CDF). I assisted in the design and constuction of the test beam facility gas delivery system, and I conducted the initial studies to document the ability of the MT beamline to meet the needs of CDF. Analysis of the preliminary performance data on MT beamline components and beam tunes at required particle energies is presented. Preliminary studies show that the MT beamline has the necessary flexibility to satisfy most CDF requirements now

  18. NCAR Earth Observing Laboratory - An End-to-End Observational Science Enterprise

    Science.gov (United States)

    Rockwell, A.; Baeuerle, B.; Grubišić, V.; Hock, T. F.; Lee, W. C.; Ranson, J.; Stith, J. L.; Stossmeister, G.

    2017-12-01

    Researchers who want to understand and describe the Earth System require high-quality observations of the atmosphere, ocean, and biosphere. Making these observations not only requires capable research platforms and state-of-the-art instrumentation but also benefits from comprehensive in-field project management and data services. NCAR's Earth Observing Laboratory (EOL) is an end-to-end observational science enterprise that provides leadership in observational research to scientists from universities, U.S. government agencies, and NCAR. Deployment: EOL manages the majority of the NSF Lower Atmosphere Observing Facilities, which includes research aircraft, radars, lidars, profilers, and surface and sounding systems. This suite is designed to address a wide range of Earth system science - from microscale to climate process studies and from the planet's surface into the Upper Troposphere/Lower Stratosphere. EOL offers scientific, technical, operational, and logistics support to small and large field campaigns across the globe. Development: By working closely with the scientific community, EOL's engineering and scientific staff actively develop the next generation of observing facilities, staying abreast of emerging trends, technologies, and applications in order to improve our measurement capabilities. Through our Design and Fabrication Services, we also offer high-level engineering and technical expertise, mechanical design, and fabrication to the atmospheric research community. Data Services: EOL's platforms and instruments collect unique datasets that must be validated, archived, and made available to the research community. EOL's Data Management and Services deliver high-quality datasets and metadata in ways that are transparent, secure, and easily accessible. We are committed to the highest standard of data stewardship from collection to validation to archival. Discovery: EOL promotes curiosity about Earth science, and fosters advanced understanding of the

  19. Status report of the end-to-end ASKAP software system: towards early science operations

    Science.gov (United States)

    Guzman, Juan Carlos; Chapman, Jessica; Marquarding, Malte; Whiting, Matthew

    2016-08-01

    300 MHz bandwidth for Array Release 1; followed by the deployment of the real-time data processing components. In addition to the Central Processor, the first production release of the CSIRO ASKAP Science Data Archive (CASDA) has also been deployed in one of the Pawsey Supercomputing Centre facilities and it is integrated to the end-to-end ASKAP data flow system. This paper describes the current status of the "end-to-end" data flow software system from preparing observations to data acquisition, processing and archiving; and the challenges of integrating an HPC facility as a key part of the instrument. It also shares some lessons learned since the start of integration activities and the challenges ahead in preparation for the start of the Early Science program.

  20. End-to-side and end-to-end anastomoses give similar results in cervical oesophagogastrostomy.

    Science.gov (United States)

    Pierie, J P; De Graaf, P W; Poen, H; Van Der Tweel, I; Obertop, H

    1995-12-01

    To find out if there were any differences in healing between end-to-end and end-to-side anastomoses for oesophagogastrostomy. Open study with historical controls. University hospital, The Netherlands. 28 patients with end-to-end and 90 patients with end-to-side anastomoses after transhiatal oesophagectomy and partial gastrectomy for cancer of the oesophagus or oesophagogastric junction, with gastric tube reconstruction and cervical anastomosis. Leak and stricture rates, and the number of dilatations needed to relieve dysphagia. There were no significant differences in leak rates (end-to-end 4/28, 14%, and end-to-side 13/90, 14%) or anastomotic strictures (end-to-end 9/28, 32%, and end-to-side 26/90, 29%). The median number of dilatations needed to relieve dysphagia was 7 (1-33) after end-to-end and 9 (1-113) after end-to-side oesophagogastrostomy. There were no differences between the two methods of suture of cervical oesophagogastrostomy when leakage, stricture, and number of dilatations were used as criteria of good healing.

  1. Beamlines of the biomedical imaging and therapy facility at the Canadian light source-Part 1

    International Nuclear Information System (INIS)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2007-01-01

    The BioMedical Imaging and Therapy (BMIT) Facility will provide synchrotron-specific imaging and therapy capabilities. This paper describes one of the BMIT beamlines: the bend magnet (BM) beamline 05B1-1. It plays a complementary role to the insertion device (ID) beamline 051D-2 and allows either monochromatic or filtered white beam to be used in the experimental hutch. The monochromatic spectral range will span 8-40 keV, and the beam is more than 200 mm wide in the experimental hutch for imaging studies of small and medium-size animals (up to sheep size). The experimental hutch will have a positioning system that will allow imaging (computed tomography and planar imaging) as well as radiation therapy applications with both filtered white and monochromatic X-ray beams and will handle subjects up to 120 kg. Several different focal plane detectors (cameras) will be available with resolutions ranging from 10 to 150 μm

  2. Radiation field characterization and shielding studies for the ELI Beamlines facility

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, A., E-mail: a.ferrari@hzdr.de [Institute of Radiation Physics, Helmholtz-Zentrum Dresden-Rossendorf, PF 510119, 01314 Dresden (Germany); Amato, E. [Department of Radiological Sciences, Messina University (Italy); Margarone, D. [ELI Beamlines Project, Institute of Physics of the ASCR, Na Slovance 2, 18221 Prague (Czech Republic); PALS Centre, Za Slovankou, 18200 Prague (Czech Republic); Cowan, T. [Institute of Radiation Physics, Helmholtz-Zentrum Dresden-Rossendorf, PF 510119, 01314 Dresden (Germany); Korn, G. [ELI Beamlines Project, Institute of Physics of the ASCR, Na Slovance 2, 18221 Prague (Czech Republic)

    2013-05-01

    The ELI (Extreme Light Infrastructure) Beamlines facility in the Czech Republic, which is planned to complete the installation in 2015, is one of the four pillars of the ELI European project. Several laser beamlines with ultrahigh intensities and ultrashort pulses are foreseen, offering versatile radiation sources in an unprecedented energy range: laser-driven particle beams are expected to range between 1 and 50 GeV for electrons and from 100 MeV up to 3 GeV for protons. The number of particles delivered per laser shot is estimated to be 10{sup 9}–10{sup 10} for the electron beams and 10{sup 10}–10{sup 12} for the proton beams. The high energy and current values of the produced particles, together with the potentiality to operate at 10 Hz laser repetition rate, require an accurate study of the primary and secondary radiation fields to optimize appropriate shielding solutions: this is a key issue to minimize prompt and residual doses in order to protect the personnel, reduce the radiation damage of electronic devices and avoid strong limitations in the operational time. A general shielding study for the 10 PW (0.016 Hz) and 2 PW (10 Hz) laser beamlines is presented here. Starting from analytical calculations, as well as from dedicated simulations, the main electron and proton fields produced in the laser-matter interaction have been described and used to characterize the “source terms” in full simulations with the Monte Carlo code FLUKA. The secondary radiation fields have been then analyzed to assess a proper shielding. The results of this study and the proposed solutions for the beam dumps of the high energy beamlines, together with a cross-check analysis performed with the Monte Carlo code GEANT4, are presented.

  3. Automatic provisioning of end-to-end QoS into the home

    DEFF Research Database (Denmark)

    Brewka, Lukasz Jerzy; Skoldström, Pontus; Nelis, Jelle

    2011-01-01

    Due to a growing number of high bandwidth applications today (such as HDTV), and an increasing amount of network and cloud based applications, service providers need to pay attention to QoS in their networks. We believe there is a need for an end-to-end approach reaching into the home as well....... The Home Gateway (HG) as a key component of the home network is crucial for enabling the end-to-end solutions. UPnP-QoS has been proposed as an inhome solution for resource reservations. In this paper we assess a solution for automatic QoS reservations, on behalf of non-UPnP-QoS aware applications....... Additionally we focus on an integrated end-to-end solution, combining GMPLS-based reservations in e.g., access/metro and UPnP-QoS based reservation in the home network....

  4. SUNY beamline facilities at the National Synchrotron Light Source (Final Report)

    International Nuclear Information System (INIS)

    Coppens, Philip

    2003-01-01

    The DOE sponsored SUNY synchrotron project has involved close cooperation among faculty at several SUNY campuses. A large number of students and postdoctoral associates have participated in its operation which was centered at the X3 beamline of the National Synchrotron Light Source at Brookhaven National Laboratory. Four stations with capabilities for Small Angle Scattering, Single Crystal and Powder and Surface diffraction and EXAFS were designed and operated with capability to perform experiments at very low as well as elevated temperatures and under high vacuum. A large amount of cutting-edge science was performed at the facility, which in addition provided excellent training for students and postdoctoral scientists in the field

  5. SUNY beamline facilities at the National Synchrotron Light Source (Final Report)

    Energy Technology Data Exchange (ETDEWEB)

    Coppens, Philip

    2003-06-22

    The DOE sponsored SUNY synchrotron project has involved close cooperation among faculty at several SUNY campuses. A large number of students and postdoctoral associates have participated in its operation which was centered at the X3 beamline of the National Synchrotron Light Source at Brookhaven National Laboratory. Four stations with capabilities for Small Angle Scattering, Single Crystal and Powder and Surface diffraction and EXAFS were designed and operated with capability to perform experiments at very low as well as elevated temperatures and under high vacuum. A large amount of cutting-edge science was performed at the facility, which in addition provided excellent training for students and postdoctoral scientists in the field.

  6. Security Considerations around End-to-End Security in the IP-based Internet of Things

    NARCIS (Netherlands)

    Brachmann, M.; Garcia-Mochon, O.; Keoh, S.L.; Kumar, S.S.

    2012-01-01

    The IP-based Internet of Things refers to the interconnection of smart objects in a Low-power and Lossy Network (LLN) with the Internetby means of protocols such as 6LoWPAN or CoAP. The provisioning of an end-to-end security connection is the key to ensure basic functionalities such as software

  7. QoC-based Optimization of End-to-End M-Health Data Delivery Services

    NARCIS (Netherlands)

    Widya, I.A.; van Beijnum, Bernhard J.F.; Salden, Alfons

    2006-01-01

    This paper addresses how Quality of Context (QoC) can be used to optimize end-to-end mobile healthcare (m-health) data delivery services in the presence of alternative delivery paths, which is quite common in a pervasive computing and communication environment. We propose min-max-plus based

  8. End-to-End Availability Analysis of IMS-Based Networks

    DEFF Research Database (Denmark)

    Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

    2013-01-01

    Generation Networks (NGNs). In this paper, an end-to-end availability model is proposed and evaluated using a combination of Reliability Block Diagrams (RBD) and a proposed five-state Markov model. The overall availability for intra- and inter domain communication in IMS is analyzed, and the state...

  9. Location Assisted Vertical Handover Algorithm for QoS Optimization in End-to-End Connections

    DEFF Research Database (Denmark)

    Dam, Martin S.; Christensen, Steffen R.; Mikkelsen, Lars M.

    2012-01-01

    implementation on Android based tablets. The simulations cover a wide range of scenarios for two mobile users in an urban area with ubiquitous cellular coverage, and shows our algorithm leads to increased throughput, with fewer handovers, when considering the end-to-end connection than to other handover schemes...

  10. End-to-End Delay Model for Train Messaging over Public Land Mobile Networks

    Directory of Open Access Journals (Sweden)

    Franco Mazzenga

    2017-11-01

    Full Text Available Modern train control systems rely on a dedicated radio network for train to ground communications. A number of possible alternatives have been analysed to adopt the European Rail Traffic Management System/European Train Control System (ERTMS/ETCS control system on local/regional lines to improve transport capacity. Among them, a communication system based on public networks (cellular&satellite provides an interesting, effective and alternative solution to proprietary and expensive radio networks. To analyse performance of this solution, it is necessary to model the end-to-end delay and message loss to fully characterize the message transfer process from train to ground and vice versa. Starting from the results of a railway test campaign over a 300 km railway line for a cumulative 12,000 traveled km in 21 days, in this paper, we derive a statistical model for the end-to-end delay required for delivering messages. In particular, we propose a two states model allowing for reproducing the main behavioral characteristics of the end-to-end delay as observed experimentally. Model formulation has been derived after deep analysis of the recorded experimental data. When it is applied to model a realistic scenario, it allows for explicitly accounting for radio coverage characteristics, the received power level, the handover points along the line and for the serving radio technology. As an example, the proposed model is used to generate the end-to-end delay profile in a realistic scenario.

  11. End-to-end Configuration of Wireless Realtime Communication over Heterogeneous Protocols

    DEFF Research Database (Denmark)

    Malinowsky, B.; Grønbæk, Jesper; Schwefel, Hans-Peter

    2015-01-01

    This paper describes a wireless real-time communication system design using two Time Division Multiple Access (TDMA) protocols. Messages are subject to prioritization and queuing. For this interoperation scenario, we show a method for end-to-end configuration of protocols and queue sizes. Such co...

  12. Coupling of a single quantum emitter to end-to-end aligned silver nanowires

    DEFF Research Database (Denmark)

    Kumar, Shailesh; Huck, Alexander; Chen, Yuntian

    2013-01-01

    We report on the observation of coupling a single nitrogen vacancy (NV) center in a nanodiamond crystal to a propagating plasmonic mode of silver nanowires. The nanocrystal is placed either near the apex of a single silver nanowire or in the gap between two end-to-end aligned silver nanowires. We...

  13. End-to-End Flow Control for Visual-Haptic Communication under Bandwidth Change

    Science.gov (United States)

    Yashiro, Daisuke; Tian, Dapeng; Yakoh, Takahiro

    This paper proposes an end-to-end flow controller for visual-haptic communication. A visual-haptic communication system transmits non-real-time packets, which contain large-size visual data, and real-time packets, which contain small-size haptic data. When the transmission rate of visual data exceeds the communication bandwidth, the visual-haptic communication system becomes unstable owing to buffer overflow. To solve this problem, an end-to-end flow controller is proposed. This controller determines the optimal transmission rate of visual data on the basis of the traffic conditions, which are estimated by the packets for haptic communication. Experimental results confirm that in the proposed method, a short packet-sending interval and a short delay are achieved under bandwidth change, and thus, high-precision visual-haptic communication is realized.

  14. End-to-end network models encompassing terrestrial, wireless, and satellite components

    Science.gov (United States)

    Boyarko, Chandler L.; Britton, John S.; Flores, Phil E.; Lambert, Charles B.; Pendzick, John M.; Ryan, Christopher M.; Shankman, Gordon L.; Williams, Ramon P.

    2004-08-01

    Development of network models that reflect true end-to-end architectures such as the Transformational Communications Architecture need to encompass terrestrial, wireless and satellite component to truly represent all of the complexities in a world wide communications network. Use of best-in-class tools including OPNET, Satellite Tool Kit (STK), Popkin System Architect and their well known XML-friendly definitions, such as OPNET Modeler's Data Type Description (DTD), or socket-based data transfer modules, such as STK/Connect, enable the sharing of data between applications for more rapid development of end-to-end system architectures and a more complete system design. By sharing the results of and integrating best-in-class tools we are able to (1) promote sharing of data, (2) enhance the fidelity of our results and (3) allow network and application performance to be viewed in the context of the entire enterprise and its processes.

  15. Providing end-to-end QoS for multimedia applications in 3G wireless networks

    Science.gov (United States)

    Guo, Katherine; Rangarajan, Samapth; Siddiqui, M. A.; Paul, Sanjoy

    2003-11-01

    As the usage of wireless packet data services increases, wireless carriers today are faced with the challenge of offering multimedia applications with QoS requirements within current 3G data networks. End-to-end QoS requires support at the application, network, link and medium access control (MAC) layers. We discuss existing CDMA2000 network architecture and show its shortcomings that prevent supporting multiple classes of traffic at the Radio Access Network (RAN). We then propose changes in RAN within the standards framework that enable support for multiple traffic classes. In addition, we discuss how Session Initiation Protocol (SIP) can be augmented with QoS signaling for supporting end-to-end QoS. We also review state of the art scheduling algorithms at the base station and provide possible extensions to these algorithms to support different classes of traffic as well as different classes of users.

  16. Rectovaginal fistula following colectomy with an end-to-end anastomosis stapler for a colorectal adenocarcinoma.

    Science.gov (United States)

    Klein, A; Scotti, S; Hidalgo, A; Viateau, V; Fayolle, P; Moissonnier, P

    2006-12-01

    An 11-year-old, female neutered Labrador retriever was presented with a micro-invasive differentiated papillar adenocarcinoma at the colorectal junction. A colorectal end-to-end anastomosis stapler device was used to perform resection and anastomosis using a transanal technique. A rectovaginal fistula was diagnosed two days later. An exploratory laparotomy was conducted and the fistula was identified and closed. Early dehiscence of the colon was also suspected and another colorectal anastomosis was performed using a manual technique. Comparison to a conventional manual technique of intestinal surgery showed that the use of an automatic staple device was quicker and easier. To the authors' knowledge, this is the first report of a rectovaginal fistula occurring after end-to-end anastomosis stapler colorectal resection-anastomosis in the dog. To minimise the risk of this potential complication associated with the limited surgical visibility, adequate tissue retraction and inspection of the anastomosis site are essential.

  17. End-to-end delay analysis in wireless sensor networks with service vacation

    KAUST Repository

    Alabdulmohsin, Ibrahim; Hyadi, Amal; Afify, Laila H.; Shihada, Basem

    2014-01-01

    In this paper, a delay-sensitive multi-hop wireless sensor network is considered, employing an M/G/1 with vacations framework. Sensors transmit measurements to a predefined data sink subject to maximum end-to-end delay constraint. In order to prolong the battery lifetime, a sleeping scheme is adopted throughout the network nodes. The objective of our proposed framework is to present an expression for maximum hop-count as well as an approximate expression of the probability of blocking at the sink node upon violating certain end-to-end delay threshold. Using numerical simulations, we validate the proposed analytical model and demonstrate that the blocking probability of the system for various vacation time distributions matches the simulation results.

  18. End-to-end delay analysis in wireless sensor networks with service vacation

    KAUST Repository

    Alabdulmohsin, Ibrahim

    2014-04-01

    In this paper, a delay-sensitive multi-hop wireless sensor network is considered, employing an M/G/1 with vacations framework. Sensors transmit measurements to a predefined data sink subject to maximum end-to-end delay constraint. In order to prolong the battery lifetime, a sleeping scheme is adopted throughout the network nodes. The objective of our proposed framework is to present an expression for maximum hop-count as well as an approximate expression of the probability of blocking at the sink node upon violating certain end-to-end delay threshold. Using numerical simulations, we validate the proposed analytical model and demonstrate that the blocking probability of the system for various vacation time distributions matches the simulation results.

  19. Development of a Dynamic, End-to-End Free Piston Stirling Convertor Model

    Science.gov (United States)

    Regan, Timothy F.; Gerber, Scott S.; Roth, Mary Ellen

    2003-01-01

    A dynamic model for a free-piston Stirling convertor is being developed at the NASA Glenn Research Center. The model is an end-to-end system model that includes the cycle thermodynamics, the dynamics, and electrical aspects of the system. The subsystems of interest are the heat source, the springs, the moving masses, the linear alternator, the controller and the end-user load. The envisioned use of the model will be in evaluating how changes in a subsystem could affect the operation of the convertor. The model under development will speed the evaluation of improvements to a subsystem and aid in determining areas in which most significant improvements may be found. One of the first uses of the end-to-end model will be in the development of controller architectures. Another related area is in evaluating changes to details in the linear alternator.

  20. Building dialogue POMDPs from expert dialogues an end-to-end approach

    CERN Document Server

    Chinaei, Hamidreza

    2016-01-01

    This book discusses the Partially Observable Markov Decision Process (POMDP) framework applied in dialogue systems. It presents POMDP as a formal framework to represent uncertainty explicitly while supporting automated policy solving. The authors propose and implement an end-to-end learning approach for dialogue POMDP model components. Starting from scratch, they present the state, the transition model, the observation model and then finally the reward model from unannotated and noisy dialogues. These altogether form a significant set of contributions that can potentially inspire substantial further work. This concise manuscript is written in a simple language, full of illustrative examples, figures, and tables. Provides insights on building dialogue systems to be applied in real domain Illustrates learning dialogue POMDP model components from unannotated dialogues in a concise format Introduces an end-to-end approach that makes use of unannotated and noisy dialogue for learning each component of dialogue POM...

  1. Circular myotomy as an aid to resection and end-to-end anastomosis of the esophagus.

    Science.gov (United States)

    Attum, A A; Hankins, J R; Ngangana, J; McLaughlin, J S

    1979-08-01

    Segments ranging from 40 to 70% of the thoracic esophagus were resected in 80 mongrel dogs. End-to-end anastomosis was effected after circular myotomy either proximal or distal, or both proximal and distal, to the anastomosis. Among dogs undergoing resection of 60% of the esophagus, distal myotomy enabled 6 of 8 animals to survive, and combined proximal and distal myotomy permitted 8 of 10 to survive. Cineesophagography was performed in a majority of the 50 surviving animals and showed no appreciable delay of peristalsis at the myotomy sites. When these sites were examined at postmortem examination up to 13 months after operation, 1 dog showed a small diverticulum but none showed dilatation or stricture. It is concluded that circular myotomy holds real promise as a means of extending the clinical application of esophageal resection with end-to-end anastomosis.

  2. Financing the End-to-end Supply Chain: A Reference Guide to Supply Chain Finance

    OpenAIRE

    Templar, Simon; Hofmann, Erik; Findlay, Charles

    2016-01-01

    Financing the End to End Supply Chain provides readers with a real insight into the increasingly important area of supply chain finance. It demonstrates the importance of the strategic relationship between the physical supply of goods and services and the associated financial flows. The book provides a clear introduction, demonstrating the importance of the strategic relationship between supply chain and financial communities within an organization. It contains vital information on how supply...

  3. STS/DBS power subsystem end-to-end stability margin

    Science.gov (United States)

    Devaux, R. N.; Vattimo, R. J.; Peck, S. R.; Baker, W. E.

    Attention is given to a full-up end-to-end subsystem stability test which was performed with a flight solar array providing power to a fully operational spacecraft. The solar array simulator is described, and a comparison is made between test results obtained with the simulator and those obtained with the actual array. It is concluded that stability testing with a fully integrated spacecraft is necessary to ensure that all elements have been adequately modeled.

  4. Testing Application (End-to-End Performance of Networks With EFT Traffic

    Directory of Open Access Journals (Sweden)

    Vlatko Lipovac

    2009-01-01

    Full Text Available This paper studies how end-to-end application peiformance(of Electronic Financial Transaction traffic, in particulardepends on the actual protocol stacks, operating systemsand network transmission rates. With this respect, the respectivesimulation tests of peiformance of TCP and UDP protocolsrunning on various operating systems, ranging from Windows,Sun Solmis, to Linux have been implemented, and thedifferences in peiformance addressed focusing on throughputand response time.

  5. Experimental evaluation of end-to-end delay in switched Ethernet application in the automotive domain

    OpenAIRE

    Beretis , Kostas; Symeonidis , Ieroklis

    2013-01-01

    International audience; This article presents an approach for deriving upper bound for end-to-end delay in a double star switched Ethernet network. Four traffic classes, following a strict priority queuing policy, were considered. The theoretical analysis was based on network calculus. An experimental setup, which accu-rately reflects an automotive communication network, was implemented in or-der to evaluate the theoretical model. The results obtained by the experiments provided valuable feed...

  6. End-to-end System Performance Simulation: A Data-Centric Approach

    Science.gov (United States)

    Guillaume, Arnaud; Laffitte de Petit, Jean-Luc; Auberger, Xavier

    2013-08-01

    In the early times of space industry, the feasibility of Earth observation missions was directly driven by what could be achieved by the satellite. It was clear to everyone that the ground segment would be able to deal with the small amount of data sent by the payload. Over the years, the amounts of data processed by the spacecrafts have been increasing drastically, leading to put more and more constraints on the ground segment performances - and in particular on timeliness. Nowadays, many space systems require high data throughputs and short response times, with information coming from multiple sources and involving complex algorithms. It has become necessary to perform thorough end-to-end analyses of the full system in order to optimise its cost and efficiency, but even sometimes to assess the feasibility of the mission. This paper presents a novel framework developed by Astrium Satellites in order to meet these needs of timeliness evaluation and optimisation. This framework, named ETOS (for “End-to-end Timeliness Optimisation of Space systems”), provides a modelling process with associated tools, models and GUIs. These are integrated thanks to a common data model and suitable adapters, with the aim of building suitable space systems simulators of the full end-to-end chain. A big challenge of such environment is to integrate heterogeneous tools (each one being well-adapted to part of the chain) into a relevant timeliness simulation.

  7. CHEETAH: circuit-switched high-speed end-to-end transport architecture

    Science.gov (United States)

    Veeraraghavan, Malathi; Zheng, Xuan; Lee, Hyuk; Gardner, M.; Feng, Wuchun

    2003-10-01

    Leveraging the dominance of Ethernet in LANs and SONET/SDH in MANs and WANs, we propose a service called CHEETAH (Circuit-switched High-speed End-to-End Transport ArcHitecture). The service concept is to provide end hosts with high-speed, end-to-end circuit connectivity on a call-by-call shared basis, where a "circuit" consists of Ethernet segments at the ends that are mapped into Ethernet-over-SONET long-distance circuits. This paper focuses on the file-transfer application for such circuits. For this application, the CHEETAH service is proposed as an add-on to the primary Internet access service already in place for enterprise hosts. This allows an end host that is sending a file to first attempt setting up an end-to-end Ethernet/EoS circuit, and if rejected, fall back to the TCP/IP path. If the circuit setup is successful, the end host will enjoy a much shorter file-transfer delay than on the TCP/IP path. To determine the conditions under which an end host with access to the CHEETAH service should attempt circuit setup, we analyze mean file-transfer delays as a function of call blocking probability in the circuit-switched network, probability of packet loss in the IP network, round-trip times, link rates, and so on.

  8. QoS Modeling for End-to-End Performance Evaluation over Networks with Wireless Access

    Directory of Open Access Journals (Sweden)

    Gómez Gerardo

    2010-01-01

    Full Text Available This paper presents an end-to-end Quality of Service (QoS model for assessing the performance of data services over networks with wireless access. The proposed model deals with performance degradation across protocol layers using a bottom-up strategy, starting with the physical layer and moving on up to the application layer. This approach makes it possible to analytically assess performance at different layers, thereby facilitating a possible end-to-end optimization process. As a representative case, a scenario where a set of mobile terminals connected to a streaming server through an IP access node has been studied. UDP, TCP, and the new TCP-Friendly Rate Control (TFRC protocols were analyzed at the transport layer. The radio interface consisted of a variable-rate multiuser and multichannel subsystem, including retransmissions and adaptive modulation and coding. The proposed analytical QoS model was validated on a real-time emulator of an end-to-end network with wireless access and proved to be very useful for the purposes of service performance estimation and optimization.

  9. Outcome of end-to-end urethroplasty in post-traumatic stricture of posterior urethra.

    Science.gov (United States)

    Hussain, Akbar; Pansota, Mudassar Saeed; Rasool, Mumtaz; Tabassum, Shafqat Ali; Ahmad, Iftikhar; Saleem, Muhammad Shahzad

    2013-04-01

    To determine the outcome of delayed end-to-end anastomotic urethroplasty in blind post-traumatic stricture of posterior urethra at our setup. Case series. Department of Urology and Renal Transplantation, Quaid-e-Azam Medical College/Bahawal Victoria Hospital, Bahawalpur, from January 2009 to June 2011. Adult patients with completely obliterated post-traumatic stricture of posterior urethra ≤ 2 cm were included in the study. Patients with post-prostatectomy (TUR-P, TVP) stricture, stricture more than 2 cm in size or patients of stricture with neurogenic bladder and patients with any perineal disease were excluded from the study. Retrograde urethrogram and voiding cysto-urethrogram was done in every patient to assess stricture length and location. Stricture excision and delayed end-to-end anastomosis of urethra with spatulation was performed in every patient. Minimum followup period was 6 months and maximum 18 months. There were 26 cases with road traffic accident (indirect) and 14 had history of fall/direct trauma to perineum or urethra. Majority of the patients (57.5%) were between 16 to 30 years of age. Twelve (30.0%) patients developed complications postoperatively. Early complications of wound infection occurred in 01 (2.5%) patient. Late complications were seen in 11 (27.5%) patients i.e. stricture recurrence in 7 (17.5%), erectile dysfunction in 2 (5.0%), urethrocutaneous fistula and urinary incontinence in one patient (2.5%) each. Success rate was 70.0% initially and 87.5% overall. Delayed end-to-end anastomotic urethroplasty is an effective procedure for traumatic posterior urethral strictures with success rate of about 87.5%.

  10. Reversible end-to-end assembly of gold nanorods using a disulfide-modified polypeptide

    International Nuclear Information System (INIS)

    Walker, David A; Gupta, Vinay K

    2008-01-01

    Directing the self-assembly of colloidal particles into nanostructures is of great interest in nanotechnology. Here, reversible end-to-end assembly of gold nanorods (GNR) is induced by pH-dependent changes in the secondary conformation of a disulfide-modified poly(L-glutamic acid) (SSPLGA). The disulfide anchoring group drives chemisorption of the polyacid onto the end of the gold nanorods in an ethanolic solution. A layer of poly(vinyl pyrrolidone) is adsorbed on the positively charged, surfactant-stabilized GNR to screen the surfactant bilayer charge and provide stability for dispersion of the GNR in ethanol. For comparison, irreversible end-to-end assembly using a bidentate ligand, namely 1,6-hexanedithiol, is also performed. Characterization of the modified GNR and its end-to-end linking behavior using SSPLGA and hexanedithiol is performed using dynamic light scattering (DLS), UV-vis absorption spectroscopy and transmission electron microscopy (TEM). Experimental results show that, in a colloidal solution of GNR-SSPLGA at a pH∼3.5, where the PLGA is in an α-helical conformation, the modified GNR self-assemble into one-dimensional nanostructures. The linking behavior can be reversed by increasing the pH (>8.5) to drive the conformation of the polypeptide to a random coil and this reversal with pH occurs rapidly within minutes. Cycling the pH multiple times between low and high pH values can be used to drive the formation of the nanostructures of the GNR and disperse them in solution.

  11. Outcome of end-to-end urethroplasty in post-traumatic stricture of posterior urethra

    International Nuclear Information System (INIS)

    Hussain, A.; Pansota, M. S.; Rasool, M.; Tabassum, S. A.; Ahmad, I.; Saleem, M. S.

    2013-01-01

    Objective: To determine the outcome of delayed end-to-end anastomotic urethroplasty in blind post-traumatic stricture of posterior urethra at our setup. Study Design: Case series. Place and Duration of Study: Department of Urology and Renal Transplantation, Quaid-e-Azam Medical College/ Bahawal Victoria Hospital, Bahawalpur, from January 2009 to June 2011. Methodology: Adult patients with completely obliterated post-traumatic stricture of posterior urethra 2 cm/sup 2/ were included in the study. Patients with post-prostatectomy (TUR-P, TVP) stricture, stricture more than 2 cm in size or patients of stricture with neurogenic bladder and patients with any perineal disease were excluded from the study. Retrograde urethrogram and voiding cysto-urethrogram was done in every patient to assess stricture length and location. Stricture excision and delayed end-to-end anastomosis of urethra with spatulation was performed in every patient. Minimum followup period was 6 months and maximum 18 months. Results: There were 26 cases with road traffic accident (indirect) and 14 had history of fall/direct trauma to perineum or urethra. Majority of the patients (57.5%) were between 16 to 30 years of age. Twelve (30.0%) patients developed complications postoperatively. Early complications of wound infection occurred in 01 (2.5%) patient. Late complications were seen in 11 (27.5%) patients i.e. stricture recurrence in 7 (17.5%), erectile dysfunction in 2 (5.0%), urethrocutaneous fistula and urinary incontinence in one patient (2.5%) each. Success rate was 70.0% initially and 87.5% overall. Conclusion: Delayed end-to-end anastomotic urethroplasty is an effective procedure for traumatic posterior urethral strictures with success rate of about 87.5%. (author)

  12. Outcome of end-to-end urethroplasty in post-traumatic stricture of posterior urethra

    Energy Technology Data Exchange (ETDEWEB)

    Hussain, A.; Pansota, M. S.; Rasool, M.; Tabassum, S. A.; Ahmad, I.; Saleem, M. S. [Bahawal Victoria Hospital, Bahawalpur (Pakistan). Dept. of Urology

    2013-04-15

    Objective: To determine the outcome of delayed end-to-end anastomotic urethroplasty in blind post-traumatic stricture of posterior urethra at our setup. Study Design: Case series. Place and Duration of Study: Department of Urology and Renal Transplantation, Quaid-e-Azam Medical College/ Bahawal Victoria Hospital, Bahawalpur, from January 2009 to June 2011. Methodology: Adult patients with completely obliterated post-traumatic stricture of posterior urethra 2 cm/sup 2/ were included in the study. Patients with post-prostatectomy (TUR-P, TVP) stricture, stricture more than 2 cm in size or patients of stricture with neurogenic bladder and patients with any perineal disease were excluded from the study. Retrograde urethrogram and voiding cysto-urethrogram was done in every patient to assess stricture length and location. Stricture excision and delayed end-to-end anastomosis of urethra with spatulation was performed in every patient. Minimum followup period was 6 months and maximum 18 months. Results: There were 26 cases with road traffic accident (indirect) and 14 had history of fall/direct trauma to perineum or urethra. Majority of the patients (57.5%) were between 16 to 30 years of age. Twelve (30.0%) patients developed complications postoperatively. Early complications of wound infection occurred in 01 (2.5%) patient. Late complications were seen in 11 (27.5%) patients i.e. stricture recurrence in 7 (17.5%), erectile dysfunction in 2 (5.0%), urethrocutaneous fistula and urinary incontinence in one patient (2.5%) each. Success rate was 70.0% initially and 87.5% overall. Conclusion: Delayed end-to-end anastomotic urethroplasty is an effective procedure for traumatic posterior urethral strictures with success rate of about 87.5%. (author)

  13. Optimizing End-to-End Big Data Transfers over Terabits Network Infrastructure

    International Nuclear Information System (INIS)

    Kim, Youngjae; Vallee, Geoffroy R.; Lee, Sangkeun; Shipman, Galen M.

    2016-01-01

    While future terabit networks hold the promise of significantly improving big-data motion among geographically distributed data centers, significant challenges must be overcome even on today's 100 gigabit networks to realize end-to-end performance. Multiple bottlenecks exist along the end-to-end path from source to sink, for instance, the data storage infrastructure at both the source and sink and its interplay with the wide-area network are increasingly the bottleneck to achieving high performance. In this study, we identify the issues that lead to congestion on the path of an end-to-end data transfer in the terabit network environment, and we present a new bulk data movement framework for terabit networks, called LADS. LADS exploits the underlying storage layout at each endpoint to maximize throughput without negatively impacting the performance of shared storage resources for other users. LADS also uses the Common Communication Interface (CCI) in lieu of the sockets interface to benefit from hardware-level zero-copy, and operating system bypass capabilities when available. It can further improve data transfer performance under congestion on the end systems using buffering at the source using flash storage. With our evaluations, we show that LADS can avoid congested storage elements within the shared storage resource, improving input/output bandwidth, and data transfer rates across the high speed networks. We also investigate the performance degradation problems of LADS due to I/O contention on the parallel file system (PFS), when multiple LADS tools share the PFS. We design and evaluate a meta-scheduler to coordinate multiple I/O streams while sharing the PFS, to minimize the I/O contention on the PFS. Finally, with our evaluations, we observe that LADS with meta-scheduling can further improve the performance by up to 14 percent relative to LADS without meta-scheduling.

  14. Performance Enhancements of UMTS networks using end-to-end QoS provisioning

    DEFF Research Database (Denmark)

    Wang, Haibo; Prasad, Devendra; Teyeb, Oumer

    2005-01-01

    This paper investigates the end-to-end(E2E) quality of service(QoS) provisioning approaches for UMTS networks together with DiffServ IP network. The effort was put on QoS classes mapping from DiffServ to UMTS, Access Control(AC), buffering and scheduling optimization. The DiffServ Code Point (DSCP......) was utilized in the whole UMTS QoS provisioning to differentiate different type of traffics. The overall algorithm was optimized to guarantee the E2E QoS parameters of each service class, especially for realtime applications, as well as to improve the bandwidth utilization. Simulation shows that the enhanced...

  15. WiMAX security and quality of service an end-to-end perspective

    CERN Document Server

    Tang, Seok-Yee; Sharif, Hamid

    2010-01-01

    WiMAX is the first standard technology to deliver true broadband mobility at speeds that enable powerful multimedia applications such as Voice over Internet Protocol (VoIP), online gaming, mobile TV, and personalized infotainment. WiMAX Security and Quality of Service, focuses on the interdisciplinary subject of advanced Security and Quality of Service (QoS) in WiMAX wireless telecommunication systems including its models, standards, implementations, and applications. Split into 4 parts, Part A of the book is an end-to-end overview of the WiMAX architecture, protocol, and system requirements.

  16. An overview of recent end-to-end wireless medical video telemedicine systems using 3G.

    Science.gov (United States)

    Panayides, A; Pattichis, M S; Pattichis, C S; Schizas, C N; Spanias, A; Kyriacou, E

    2010-01-01

    Advances in video compression, network technologies, and computer technologies have contributed to the rapid growth of mobile health (m-health) systems and services. Wide deployment of such systems and services is expected in the near future, and it's foreseen that they will soon be incorporated in daily clinical practice. This study focuses in describing the basic components of an end-to-end wireless medical video telemedicine system, providing a brief overview of the recent advances in the field, while it also highlights future trends in the design of telemedicine systems that are diagnostically driven.

  17. Wiretapping End-to-End Encrypted VoIP Calls: Real-World Attacks on ZRTP

    Directory of Open Access Journals (Sweden)

    Schürmann Dominik

    2017-07-01

    Full Text Available Voice calls are still one of the most common use cases for smartphones. Often, sensitive personal information but also confidential business information is shared. End-to-end security is required to protect against wiretapping of voice calls. For such real-time communication, the ZRTP key-agreement protocol has been proposed. By verbally comparing a small number of on-screen characters or words, called Short Authentication Strings, the participants can be sure that no one is wiretapping the call. Since 2011, ZRTP is an IETF standard implemented in several VoIP clients.

  18. Screening California Current fishery management scenarios using the Atlantis end-to-end ecosystem model

    Science.gov (United States)

    Kaplan, Isaac C.; Horne, Peter J.; Levin, Phillip S.

    2012-09-01

    End-to-end marine ecosystem models link climate and oceanography to the food web and human activities. These models can be used as forecasting tools, to strategically evaluate management options and to support ecosystem-based management. Here we report the results of such forecasts in the California Current, using an Atlantis end-to-end model. We worked collaboratively with fishery managers at NOAA’s regional offices and staff at the National Marine Sanctuaries (NMS) to explore the impact of fishery policies on management objectives at different spatial scales, from single Marine Sanctuaries to the entire Northern California Current. In addition to examining Status Quo management, we explored the consequences of several gear switching and spatial management scenarios. Of the scenarios that involved large scale management changes, no single scenario maximized all performance metrics. Any policy choice would involve trade-offs between stakeholder groups and policy goals. For example, a coast-wide 25% gear shift from trawl to pot or longline appeared to be one possible compromise between an increase in spatial management (which sacrificed revenue) and scenarios such as the one consolidating bottom impacts to deeper areas (which did not perform substantially differently from Status Quo). Judged on a coast-wide scale, most of the scenarios that involved minor or local management changes (e.g. within Monterey Bay NMS only) yielded results similar to Status Quo. When impacts did occur in these cases, they often involved local interactions that were difficult to predict a priori based solely on fishing patterns. However, judged on the local scale, deviation from Status Quo did emerge, particularly for metrics related to stationary species or variables (i.e. habitat and local metrics of landed value or bycatch). We also found that isolated management actions within Monterey Bay NMS would cause local fishers to pay a cost for conservation, in terms of reductions in landed

  19. End to end adaptive congestion control in TCP/IP networks

    CERN Document Server

    Houmkozlis, Christos N

    2012-01-01

    This book provides an adaptive control theory perspective on designing congestion controls for packet-switching networks. Relevant to a wide range of disciplines and industries, including the music industry, computers, image trading, and virtual groups, the text extensively discusses source oriented, or end to end, congestion control algorithms. The book empowers readers with clear understanding of the characteristics of packet-switching networks and their effects on system stability and performance. It provides schemes capable of controlling congestion and fairness and presents real-world app

  20. End-to-End Assessment of a Large Aperture Segmented Ultraviolet Optical Infrared (UVOIR) Telescope Architecture

    Science.gov (United States)

    Feinberg, Lee; Bolcar, Matt; Liu, Alice; Guyon, Olivier; Stark,Chris; Arenberg, Jon

    2016-01-01

    Key challenges of a future large aperture, segmented Ultraviolet Optical Infrared (UVOIR) Telescope capable of performing a spectroscopic survey of hundreds of Exoplanets will be sufficient stability to achieve 10-10 contrast measurements and sufficient throughput and sensitivity for high yield Exo-Earth spectroscopic detection. Our team has collectively assessed an optimized end to end architecture including a high throughput coronagraph capable of working with a segmented telescope, a cost-effective and heritage based stable segmented telescope, a control architecture that minimizes the amount of new technologies, and an Exo-Earth yield assessment to evaluate potential performance.

  1. On end-to-end performance of MIMO multiuser in cognitive radio networks

    KAUST Repository

    Yang, Yuli

    2011-12-01

    In this paper, a design for the multiple-input-multiple-output (MIMO) multiuser transmission in the cognitive radio network is developed and its end-to-end performance is investigated under spectrum-sharing constraints. Firstly, the overall average packet error rate is analyzed by considering the channel state information feedback delay and the multiuser scheduling. Then, we provide corresponding numerical results to measure the performance evaluation for several separate scenarios, which presents a convenient tool for the cognitive radio network design with multiple secondary MIMO users. © 2011 IEEE.

  2. On end-to-end performance of MIMO multiuser in cognitive radio networks

    KAUST Repository

    Yang, Yuli; Aissa, Sonia

    2011-01-01

    In this paper, a design for the multiple-input-multiple-output (MIMO) multiuser transmission in the cognitive radio network is developed and its end-to-end performance is investigated under spectrum-sharing constraints. Firstly, the overall average packet error rate is analyzed by considering the channel state information feedback delay and the multiuser scheduling. Then, we provide corresponding numerical results to measure the performance evaluation for several separate scenarios, which presents a convenient tool for the cognitive radio network design with multiple secondary MIMO users. © 2011 IEEE.

  3. Analytical Framework for End-to-End Delay Based on Unidirectional Highway Scenario

    Directory of Open Access Journals (Sweden)

    Aslinda Hassan

    2015-01-01

    Full Text Available In a sparse vehicular ad hoc network, a vehicle normally employs a carry and forward approach, where it holds the message it wants to transmit until the vehicle meets other vehicles or roadside units. A number of analyses in the literature have been done to investigate the time delay when packets are being carried by vehicles on both unidirectional and bidirectional highways. However, these analyses are focusing on the delay between either two disconnected vehicles or two disconnected vehicle clusters. Furthermore, majority of the analyses only concentrate on the expected value of the end-to-end delay when the carry and forward approach is used. Using regression analysis, we establish the distribution model for the time delay between two disconnected vehicle clusters as an exponential distribution. Consequently, a distribution is newly derived to represent the number of clusters on a highway using a vehicular traffic model. From there, we are able to formulate end-to-end delay model which extends the time delay model for two disconnected vehicle clusters to multiple disconnected clusters on a unidirectional highway. The analytical results obtained from the analytical model are then validated through simulation results.

  4. Modeling and simulation of satellite subsystems for end-to-end spacecraft modeling

    Science.gov (United States)

    Schum, William K.; Doolittle, Christina M.; Boyarko, George A.

    2006-05-01

    During the past ten years, the Air Force Research Laboratory (AFRL) has been simultaneously developing high-fidelity spacecraft payload models as well as a robust distributed simulation environment for modeling spacecraft subsystems. Much of this research has occurred in the Distributed Architecture Simulation Laboratory (DASL). AFRL developers working in the DASL have effectively combined satellite power, attitude pointing, and communication link analysis subsystem models with robust satellite sensor models to create a first-order end-to-end satellite simulation capability. The merging of these two simulation areas has advanced the field of spacecraft simulation, design, and analysis, and enabled more in-depth mission and satellite utility analyses. A core capability of the DASL is the support of a variety of modeling and analysis efforts, ranging from physics and engineering-level modeling to mission and campaign-level analysis. The flexibility and agility of this simulation architecture will be used to support space mission analysis, military utility analysis, and various integrated exercises with other military and space organizations via direct integration, or through DOD standards such as Distributed Interaction Simulation. This paper discusses the results and lessons learned in modeling satellite communication link analysis, power, and attitude control subsystems for an end-to-end satellite simulation. It also discusses how these spacecraft subsystem simulations feed into and support military utility and space mission analyses.

  5. Increasing operations profitability using an end-to-end, wireless internet, gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, M. [Northrock Resources Ltd., AB (Canada); Benterud, K. [zed.i solutions, inc., Calgary, AB (Canada)

    2004-10-01

    Implementation by Northrock Resources Ltd., a wholly-owned subsidiary of Unocal Corporation, of a fully integrated end-to-end gas measurement and production analysis system, is discussed. The system, dubbed Smart-Alek(TM), utilizes public wireless communications and a web browser only delivery system to provide seamless well visibility to a desk-top computer. Smart-Alek(TM) is an example of a new type of end-to-end electronic gas flow measurement system, known as FINE(TM), which is an acronym for Field Intelligence Network and End-User Interface. The system delivers easy-to-use, complete, reliable and cost effective production information, far more effective than is possible to obtain with conventional SCADA technology. By installing the system, Northrock was able to increase gas volumes with more accurate electronic flow measurement in place of mechanical charts, with very low technical maintenance, and at a reduced operating cost. It is emphasized that deploying the technology alone will produce only partial benefits; to realize full benefits it is also essential to change grass roots operating practices, aiming at timely decision-making at the field level. 5 refs., 5 figs.

  6. An End-to-End Model of Plant Pheromone Channel for Long Range Molecular Communication.

    Science.gov (United States)

    Unluturk, Bige D; Akyildiz, Ian F

    2017-01-01

    A new track in molecular communication is using pheromones which can scale up the range of diffusion-based communication from μm meters to meters and enable new applications requiring long range. Pheromone communication is the emission of molecules in the air which trigger behavioral or physiological responses in receiving organisms. The objective of this paper is to introduce a new end-to-end model which incorporates pheromone behavior with communication theory for plants. The proposed model includes both the transmission and reception processes as well as the propagation channel. The transmission process is the emission of pheromones from the leaves of plants. The dispersion of pheromones by the flow of wind constitutes the propagation process. The reception process is the sensing of pheromones by the pheromone receptors of plants. The major difference of pheromone communication from other molecular communication techniques is the dispersion channel acting under the laws of turbulent diffusion. In this paper, the pheromone channel is modeled as a Gaussian puff, i.e., a cloud of pheromone released instantaneously from the source whose dispersion follows a Gaussian distribution. Numerical results on the performance of the overall end-to-end pheromone channel in terms of normalized gain and delay are provided.

  7. End-to-End Airplane Detection Using Transfer Learning in Remote Sensing Images

    Directory of Open Access Journals (Sweden)

    Zhong Chen

    2018-01-01

    Full Text Available Airplane detection in remote sensing images remains a challenging problem due to the complexity of backgrounds. In recent years, with the development of deep learning, object detection has also obtained great breakthroughs. For object detection tasks in natural images, such as the PASCAL (Pattern Analysis, Statistical Modelling and Computational Learning VOC (Visual Object Classes Challenge, the major trend of current development is to use a large amount of labeled classification data to pre-train the deep neural network as a base network, and then use a small amount of annotated detection data to fine-tune the network for detection. In this paper, we use object detection technology based on deep learning for airplane detection in remote sensing images. In addition to using some characteristics of remote sensing images, some new data augmentation techniques have been proposed. We also use transfer learning and adopt a single deep convolutional neural network and limited training samples to implement end-to-end trainable airplane detection. Classification and positioning are no longer divided into multistage tasks; end-to-end detection attempts to combine them for optimization, which ensures an optimal solution for the final stage. In our experiment, we use remote sensing images of airports collected from Google Earth. The experimental results show that the proposed algorithm is highly accurate and meaningful for remote sensing object detection.

  8. End to end distribution functions for a class of polymer models

    International Nuclear Information System (INIS)

    Khandekar, D.C.; Wiegel, F.W.

    1988-01-01

    The two point end-to-end distribution functions for a class of polymer models have been obtained within the first cumulant approximation. The trial distribution function this purpose is chosen to correspond to a general non-local quadratic functional. An Exact expression for the trial distribution function is obtained. It is pointed out that these trial distribution functions themselves can be used to study certain aspects of the configurational behaviours of polymers. These distribution functions are also used to obtain the averaged mean square size 2 > of a polymer characterized by the non-local quadratic potential energy functional. Finally, we derive an analytic expression for 2 > of a polyelectrolyte model and show that for a long polymer a weak electrostatic interaction does not change the behaviour of 2 > from that of a free polymer. (author). 16 refs

  9. End-to-End Assessment of a Large Aperture Segmented Ultraviolet Optical Infrared (UVOIR) Telescope Architecture

    Science.gov (United States)

    Feinberg, Lee; Rioux, Norman; Bolcar, Matthew; Liu, Alice; Guyon, Oliver; Stark, Chris; Arenberg, Jon

    2016-01-01

    Key challenges of a future large aperture, segmented Ultraviolet Optical Infrared (UVOIR) Telescope capable of performing a spectroscopic survey of hundreds of Exoplanets will be sufficient stability to achieve 10^-10 contrast measurements and sufficient throughput and sensitivity for high yield Exo-Earth spectroscopic detection. Our team has collectively assessed an optimized end to end architecture including a high throughput coronagraph capable of working with a segmented telescope, a cost-effective and heritage based stable segmented telescope, a control architecture that minimizes the amount of new technologies, and an Exo-Earth yield assessment to evaluate potential performance. These efforts are combined through integrated modeling, coronagraph evaluations, and Exo-Earth yield calculations to assess the potential performance of the selected architecture. In addition, we discusses the scalability of this architecture to larger apertures and the technological tall poles to enabling it.

  10. End-to-End Beam Simulations for the New Muon G-2 Experiment at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Korostelev, Maxim [Cockcroft Inst. Accel. Sci. Tech.; Bailey, Ian [Lancaster U.; Herrod, Alexander [Liverpool U.; Morgan, James [Fermilab; Morse, William [RIKEN BNL; Stratakis, Diktys [RIKEN BNL; Tishchenko, Vladimir [RIKEN BNL; Wolski, Andrzej [Cockcroft Inst. Accel. Sci. Tech.

    2016-06-01

    The aim of the new muon g-2 experiment at Fermilab is to measure the anomalous magnetic moment of the muon with an unprecedented uncertainty of 140 ppb. A beam of positive muons required for the experiment is created by pion decay. Detailed studies of the beam dynamics and spin polarization of the muons are important to predict systematic uncertainties in the experiment. In this paper, we present the results of beam simulations and spin tracking from the pion production target to the muon storage ring. The end-to-end beam simulations are developed in Bmad and include the processes of particle decay, collimation (with accurate representation of all apertures) and spin tracking.

  11. An end-to-end secure patient information access card system.

    Science.gov (United States)

    Alkhateeb, A; Singer, H; Yakami, M; Takahashi, T

    2000-03-01

    The rapid development of the Internet and the increasing interest in Internet-based solutions has promoted the idea of creating Internet-based health information applications. This will force a change in the role of IC cards in healthcare card systems from a data carrier to an access key medium. At the Medical Informatics Department of Kyoto University Hospital we are developing a smart card patient information project where patient databases are accessed via the Internet. Strong end-to-end data encryption is performed via Secure Socket Layers, transparent to transmit patient information. The smart card is playing the crucial role of access key to the database: user authentication is performed internally without ever revealing the actual key. For easy acceptance by healthcare professionals, the user interface is integrated as a plug-in for two familiar Web browsers, Netscape Navigator and MS Internet Explorer.

  12. End-to-End Traffic Flow Modeling of the Integrated SCaN Network

    Science.gov (United States)

    Cheung, K.-M.; Abraham, D. S.

    2012-05-01

    In this article, we describe the analysis and simulation effort of the end-to-end traffic flow for the Integrated Space Communications and Navigation (SCaN) Network. Using the network traffic derived for the 30-day period of July 2018 from the Space Communications Mission Model (SCMM), we generate the wide-area network (WAN) bandwidths of the ground links for different architecture options of the Integrated SCaN Network. We also develop a new analytical scheme to model the traffic flow and buffering mechanism of a store-and-forward network. It is found that the WAN bandwidth of the Integrated SCaN Network is an important differentiator of different architecture options, as the recurring circuit costs of certain architecture options can be prohibitively high.

  13. End-to-end operations at the National Radio Astronomy Observatory

    Science.gov (United States)

    Radziwill, Nicole M.

    2008-07-01

    In 2006 NRAO launched a formal organization, the Office of End to End Operations (OEO), to broaden access to its instruments (VLA/EVLA, VLBA, GBT and ALMA) in the most cost-effective ways possible. The VLA, VLBA and GBT are mature instruments, and the EVLA and ALMA are currently under construction, which presents unique challenges for integrating software across the Observatory. This article 1) provides a survey of the new developments over the past year, and those planned for the next year, 2) describes the business model used to deliver many of these services, and 3) discusses the management models being applied to ensure continuous innovation in operations, while preserving the flexibility and autonomy of telescope software development groups.

  14. End-to-end interoperability and workflows from building architecture design to one or more simulations

    Science.gov (United States)

    Chao, Tian-Jy; Kim, Younghun

    2015-02-10

    An end-to-end interoperability and workflows from building architecture design to one or more simulations, in one aspect, may comprise establishing a BIM enablement platform architecture. A data model defines data entities and entity relationships for enabling the interoperability and workflows. A data definition language may be implemented that defines and creates a table schema of a database associated with the data model. Data management services and/or application programming interfaces may be implemented for interacting with the data model. Web services may also be provided for interacting with the data model via the Web. A user interface may be implemented that communicates with users and uses the BIM enablement platform architecture, the data model, the data definition language, data management services and application programming interfaces to provide functions to the users to perform work related to building information management.

  15. The role of sea ports in end-to-end maritime transport chain emissions

    International Nuclear Information System (INIS)

    Gibbs, David; Rigot-Muller, Patrick; Mangan, John; Lalwani, Chandra

    2014-01-01

    This paper's purpose is to investigate the role of sea ports in helping to mitigate the GHG emissions associated with the end-to-end maritime transport chain. The analysis is primarily focused on the UK, but is international in application. The paper is based on both the analysis of secondary data and information on actions taken by ports to reduce their emissions, with the latter data collected for the main UK ports via their published reports and/or via interviews. Only a small number of ports (representing 32% of UK port activity) actually measure and report their carbon emissions in the UK context. The emissions generated by ships calling at these ports are analysed using a method based on Department for Transport Maritime Statistics Data. In addition, a case example (Felixstowe) of emissions associated with HGV movements to and from ports is presented, and data on vessel emissions at berth are also considered. Our analyses indicate that emissions generated by ships during their voyages between ports are of a far greater magnitude than those generated by the port activities. Thus while reducing the ports' own emissions is worthwhile, the results suggest that ports might have more impact through focusing their efforts on reducing shipping emissions. - Highlights: • Investigates role of ports in mitigating GHG emissions in the end-to-end maritime transport chain. • Emissions generated both by ports and by ships calling at ports are analysed. • Shipping's emissions are far greater than those generated by port activities. • Ports may have more impact through focusing efforts on reducing shipping's emissions. • Options for ports to support and drive change in the maritime sector also considered

  16. The end-to-end testbed of the optical metrology system on-board LISA Pathfinder

    Energy Technology Data Exchange (ETDEWEB)

    Steier, F; Cervantes, F Guzman; Marin, A F GarcIa; Heinzel, G; Danzmann, K [Max-Planck-Institut fuer Gravitationsphysik (Albert-Einstein-Institut) and Universitaet Hannover (Germany); Gerardi, D, E-mail: frank.steier@aei.mpg.d [EADS Astrium Satellites GmbH, Friedrichshafen (Germany)

    2009-05-07

    LISA Pathfinder is a technology demonstration mission for the Laser Interferometer Space Antenna (LISA). The main experiment on-board LISA Pathfinder is the so-called LISA Technology Package (LTP) which has the aim to measure the differential acceleration between two free-falling test masses with an accuracy of 3 x 10{sup -14} ms{sup -2} Hz{sup -1/2} between 1 mHz and 30 mHz. This measurement is performed interferometrically by the optical metrology system (OMS) on-board LISA Pathfinder. In this paper, we present the development of an experimental end-to-end testbed of the entire OMS. It includes the interferometer and its sub-units, the interferometer backend which is a phasemeter and the processing of the phasemeter output data. Furthermore, three-axes piezo-actuated mirrors are used instead of the free-falling test masses for the characterization of the dynamic behaviour of the system and some parts of the drag-free and attitude control system (DFACS) which controls the test masses and the satellite. The end-to-end testbed includes all parts of the LTP that can reasonably be tested on earth without free-falling test masses. At its present status it consists mainly of breadboard components. Some of those have already been replaced by engineering models of the LTP experiment. In the next steps, further engineering and flight models will also be inserted in this testbed and tested against well-characterized breadboard components. The presented testbed is an important reference for the unit tests and can also be used for validation of the on-board experiment during the mission.

  17. Kinetics of end-to-end collision in short single-stranded nucleic acids.

    Science.gov (United States)

    Wang, Xiaojuan; Nau, Werner M

    2004-01-28

    A novel fluorescence-based method, which entails contact quenching of the long-lived fluorescent state of 2,3-diazabicyclo[2.2.2]-oct-2-ene (DBO), was employed to measure the kinetics of end-to-end collision in short single-stranded oligodeoxyribonucleotides of the type 5'-DBO-(X)n-dG with X = dA, dC, dT, or dU and n = 2 or 4. The fluorophore was covalently attached to the 5' end and dG was introduced as an efficient intrinsic quencher at the 3' terminus. The end-to-end collision rates, which can be directly related to the efficiency of intramolecular fluorescence quenching, ranged from 0.1 to 9.0 x 10(6) s(-1). They were strongly dependent on the strand length, the base sequence, as well as the temperature. Oligonucleotides containing dA in the backbone displayed much slower collision rates and significantly higher positive activation energies than strands composed of pyrimidine bases, suggesting a higher intrinsic rigidity of oligoadenylate. Comparison of the measured collision rates in short single-stranded oligodeoxyribonucleotides with the previously reported kinetics of hairpin formation indicates that the intramolecular collision is significantly faster than the nucleation step of hairpin closing. This is consistent with the configurational diffusion model suggested by Ansari et al. (Ansari, A.; Kuznetsov, S. V.; Shen, Y. Proc.Natl. Acad. Sci. USA 2001, 98, 7771-7776), in which the formation of misfolded loops is thought to slow hairpin formation.

  18. Beamlines of the biomedical imaging and therapy facility at the Canadian light source - part 3

    Science.gov (United States)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2015-03-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1-4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6-9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20-100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to -7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT, described

  19. Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3

    International Nuclear Information System (INIS)

    Wysokinski, Tomasz W.; Chapman, Dean; Adams, Gregg; Renier, Michel; Suortti, Pekka; Thomlinson, William

    2015-01-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1–4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6–9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20–100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to –7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT

  20. Beamlines of the biomedical imaging and therapy facility at the Canadian light source – part 3

    Energy Technology Data Exchange (ETDEWEB)

    Wysokinski, Tomasz W., E-mail: bmit@lightsource.ca [Canadian Light Source, Saskatoon, SK (Canada); Chapman, Dean [Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK (Canada); Adams, Gregg [Western College of Veterinary Medicine, Saskatoon, SK (Canada); Renier, Michel [European Synchrotron Radiation Facility, Grenoble (France); Suortti, Pekka [Department of Physics, University of Helsinki (Finland); Thomlinson, William [Department of Physics, University of Saskatchewan, Saskatoon, SK (Canada)

    2015-03-01

    The BioMedical Imaging and Therapy (BMIT) facility provides synchrotron-specific imaging and radiation therapy capabilities [1–4]. We describe here the Insertion Device (ID) beamline 05ID-2 with the beam terminated in the SOE-1 (Secondary Optical Enclosure) experimental hutch. This endstation is designed for imaging and therapy research primarily in animals ranging in size from mice to humans to horses, as well as tissue specimens including plants. Core research programs include human and animal reproduction, cancer imaging and therapy, spinal cord injury and repair, cardiovascular and lung imaging and disease, bone and cartilage growth and deterioration, mammography, developmental biology, gene expression research as well as the introduction of new imaging methods. The source for the ID beamline is a multi-pole superconducting 4.3 T wiggler [5]. The high field gives a critical energy over 20 keV. The high critical energy presents shielding challenges and great care must be taken to assess shielding requirements [6–9]. The optics in the POE-1 and POE-3 hutches [4,10] prepare a monochromatic beam that is 22 cm wide in the last experimental hutch SOE-1. The double crystal bent-Laue or Bragg monochromator, or the single-crystal K-edge subtraction (KES) monochromator provide an energy range appropriate for imaging studies in animals (20–100+ keV). SOE-1 (excluding the basement structure 4 m below the experimental floor) is 6 m wide, 5 m tall and 10 m long with a removable back wall to accommodate installation and removal of the Large Animal Positioning System (LAPS) capable of positioning and manipulating animals as large as a horse [11]. This end-station also includes a unique detector positioner with a vertical travel range of 4.9 m which is required for the KES imaging angle range of +12.3° to –7.3°. The detector positioner also includes moveable shielding integrated with the safety shutters. An update on the status of the other two end-stations at BMIT

  1. Internet end-to-end performance monitoring for the High Energy Nuclear and Particle Physics community

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, W.

    2000-02-22

    Modern High Energy Nuclear and Particle Physics (HENP) experiments at Laboratories around the world present a significant challenge to wide area networks. Petabytes (1015) or exabytes (1018) of data will be generated during the lifetime of the experiment. Much of this data will be distributed via the Internet to the experiment's collaborators at Universities and Institutes throughout the world for analysis. In order to assess the feasibility of the computing goals of these and future experiments, the HENP networking community is actively monitoring performance across a large part of the Internet used by its collaborators. Since 1995, the pingER project has been collecting data on ping packet loss and round trip times. In January 2000, there are 28 monitoring sites in 15 countries gathering data on over 2,000 end-to-end pairs. HENP labs such as SLAC, Fermi Lab and CERN are using Advanced Network's Surveyor project and monitoring performance from one-way delay of UDP packets. More recently several HENP sites have become involved with NLANR's active measurement program (AMP). In addition SLAC and CERN are part of the RIPE test-traffic project and SLAC is home for a NIMI machine. The large End-to-end performance monitoring infrastructure allows the HENP networking community to chart long term trends and closely examine short term glitches across a wide range of networks and connections. The different methodologies provide opportunities to compare results based on different protocols and statistical samples. Understanding agreement and discrepancies between results provides particular insight into the nature of the network. This paper will highlight the practical side of monitoring by reviewing the special needs of High Energy Nuclear and Particle Physics experiments and provide an overview of the experience of measuring performance across a large number of interconnected networks throughout the world with various methodologies. In particular, results

  2. Internet end-to-end performance monitoring for the High Energy Nuclear and Particle Physics community

    International Nuclear Information System (INIS)

    Matthews, W.

    2000-01-01

    Modern High Energy Nuclear and Particle Physics (HENP) experiments at Laboratories around the world present a significant challenge to wide area networks. Petabytes (1015) or exabytes (1018) of data will be generated during the lifetime of the experiment. Much of this data will be distributed via the Internet to the experiment's collaborators at Universities and Institutes throughout the world for analysis. In order to assess the feasibility of the computing goals of these and future experiments, the HENP networking community is actively monitoring performance across a large part of the Internet used by its collaborators. Since 1995, the pingER project has been collecting data on ping packet loss and round trip times. In January 2000, there are 28 monitoring sites in 15 countries gathering data on over 2,000 end-to-end pairs. HENP labs such as SLAC, Fermi Lab and CERN are using Advanced Network's Surveyor project and monitoring performance from one-way delay of UDP packets. More recently several HENP sites have become involved with NLANR's active measurement program (AMP). In addition SLAC and CERN are part of the RIPE test-traffic project and SLAC is home for a NIMI machine. The large End-to-end performance monitoring infrastructure allows the HENP networking community to chart long term trends and closely examine short term glitches across a wide range of networks and connections. The different methodologies provide opportunities to compare results based on different protocols and statistical samples. Understanding agreement and discrepancies between results provides particular insight into the nature of the network. This paper will highlight the practical side of monitoring by reviewing the special needs of High Energy Nuclear and Particle Physics experiments and provide an overview of the experience of measuring performance across a large number of interconnected networks throughout the world with various methodologies. In particular, results from each project

  3. MRI simulation: end-to-end testing for prostate radiation therapy using geometric pelvic MRI phantoms

    International Nuclear Information System (INIS)

    Sun, Jidi; Menk, Fred; Lambert, Jonathan; Martin, Jarad; Denham, James W; Greer, Peter B; Dowling, Jason; Rivest-Henault, David; Pichler, Peter; Parker, Joel; Arm, Jameen; Best, Leah

    2015-01-01

    To clinically implement MRI simulation or MRI-alone treatment planning requires comprehensive end-to-end testing to ensure an accurate process. The purpose of this study was to design and build a geometric phantom simulating a human male pelvis that is suitable for both CT and MRI scanning and use it to test geometric and dosimetric aspects of MRI simulation including treatment planning and digitally reconstructed radiograph (DRR) generation.A liquid filled pelvic shaped phantom with simulated pelvic organs was scanned in a 3T MRI simulator with dedicated radiotherapy couch-top, laser bridge and pelvic coil mounts. A second phantom with the same external shape but with an internal distortion grid was used to quantify the distortion of the MR image. Both phantoms were also CT scanned as the gold-standard for both geometry and dosimetry. Deformable image registration was used to quantify the MR distortion. Dose comparison was made using a seven-field IMRT plan developed on the CT scan with the fluences copied to the MR image and recalculated using bulk electron densities.Without correction the maximum distortion of the MR compared with the CT scan was 7.5 mm across the pelvis, while this was reduced to 2.6 and 1.7 mm by the vendor’s 2D and 3D correction algorithms, respectively. Within the locations of the internal organs of interest, the distortion was <1.5 and <1 mm with 2D and 3D correction algorithms, respectively. The dose at the prostate isocentre calculated on CT and MRI images differed by 0.01% (1.1 cGy). Positioning shifts were within 1 mm when setup was performed using MRI generated DRRs compared to setup using CT DRRs.The MRI pelvic phantom allows end-to-end testing of the MRI simulation workflow with comparison to the gold-standard CT based process. MRI simulation was found to be geometrically accurate with organ dimensions, dose distributions and DRR based setup within acceptable limits compared to CT. (paper)

  4. MO-B-BRB-04: 3D Dosimetry in End-To-End Dosimetry QA

    Energy Technology Data Exchange (ETDEWEB)

    Ibbott, G. [UT MD Anderson Cancer Center (United States)

    2016-06-15

    irradiated volume can help understand interplay effects during TomoTherapy or VMAT. Titania Juang: Special techniques in the clinic and research Understand the potential for 3D dosimetry in validating dose accumulation in deformable systems, and Observe the benefits of high resolution measurements for precision therapy in SRS and in MicroSBRT for small animal irradiators Geoffrey S. Ibbott: 3D Dosimetry in end-to-end dosimetry QA Understand the potential for 3D dosimetry for end-to-end radiation therapy process validation in the in-house and external credentialing setting. Canadian Institutes of Health Research; L. Schreiner, Modus QA, London, ON, Canada; T. Juang, NIH R01CA100835.

  5. Availability and End-to-end Reliability in Low Duty Cycle Multihop Wireless Sensor Networks.

    Science.gov (United States)

    Suhonen, Jukka; Hämäläinen, Timo D; Hännikäinen, Marko

    2009-01-01

    A wireless sensor network (WSN) is an ad-hoc technology that may even consist of thousands of nodes, which necessitates autonomic, self-organizing and multihop operations. A typical WSN node is battery powered, which makes the network lifetime the primary concern. The highest energy efficiency is achieved with low duty cycle operation, however, this alone is not enough. WSNs are deployed for different uses, each requiring acceptable Quality of Service (QoS). Due to the unique characteristics of WSNs, such as dynamic wireless multihop routing and resource constraints, the legacy QoS metrics are not feasible as such. We give a new definition to measure and implement QoS in low duty cycle WSNs, namely availability and reliability. Then, we analyze the effect of duty cycling for reaching the availability and reliability. The results are obtained by simulations with ZigBee and proprietary TUTWSN protocols. Based on the results, we also propose a data forwarding algorithm suitable for resource constrained WSNs that guarantees end-to-end reliability while adding a small overhead that is relative to the packet error rate (PER). The forwarding algorithm guarantees reliability up to 30% PER.

  6. Availability and End-to-end Reliability in Low Duty Cycle MultihopWireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Timo D. Hämäläinen

    2009-03-01

    Full Text Available A wireless sensor network (WSN is an ad-hoc technology that may even consist of thousands of nodes, which necessitates autonomic, self-organizing and multihop operations. A typical WSN node is battery powered, which makes the network lifetime the primary concern. The highest energy efficiency is achieved with low duty cycle operation, however, this alone is not enough. WSNs are deployed for different uses, each requiring acceptable Quality of Service (QoS. Due to the unique characteristics of WSNs, such as dynamic wireless multihop routing and resource constraints, the legacy QoS metrics are not feasible as such. We give a new definition to measure and implement QoS in low duty cycle WSNs, namely availability and reliability. Then, we analyze the effect of duty cycling for reaching the availability and reliability. The results are obtained by simulations with ZigBee and proprietary TUTWSN protocols. Based on the results, we also propose a data forwarding algorithm suitable for resource constrained WSNs that guarantees end-to-end reliability while adding a small overhead that is relative to the packet error rate (PER. The forwarding algorithm guarantees reliability up to 30% PER.

  7. End-to-End Multimodal Emotion Recognition Using Deep Neural Networks

    Science.gov (United States)

    Tzirakis, Panagiotis; Trigeorgis, George; Nicolaou, Mihalis A.; Schuller, Bjorn W.; Zafeiriou, Stefanos

    2017-12-01

    Automatic affect recognition is a challenging task due to the various modalities emotions can be expressed with. Applications can be found in many domains including multimedia retrieval and human computer interaction. In recent years, deep neural networks have been used with great success in determining emotional states. Inspired by this success, we propose an emotion recognition system using auditory and visual modalities. To capture the emotional content for various styles of speaking, robust features need to be extracted. To this purpose, we utilize a Convolutional Neural Network (CNN) to extract features from the speech, while for the visual modality a deep residual network (ResNet) of 50 layers. In addition to the importance of feature extraction, a machine learning algorithm needs also to be insensitive to outliers while being able to model the context. To tackle this problem, Long Short-Term Memory (LSTM) networks are utilized. The system is then trained in an end-to-end fashion where - by also taking advantage of the correlations of the each of the streams - we manage to significantly outperform the traditional approaches based on auditory and visual handcrafted features for the prediction of spontaneous and natural emotions on the RECOLA database of the AVEC 2016 research challenge on emotion recognition.

  8. End-to-End Neural Optical Music Recognition of Monophonic Scores

    Directory of Open Access Journals (Sweden)

    Jorge Calvo-Zaragoza

    2018-04-01

    Full Text Available Optical Music Recognition is a field of research that investigates how to computationally decode music notation from images. Despite the efforts made so far, there are hardly any complete solutions to the problem. In this work, we study the use of neural networks that work in an end-to-end manner. This is achieved by using a neural model that combines the capabilities of convolutional neural networks, which work on the input image, and recurrent neural networks, which deal with the sequential nature of the problem. Thanks to the use of the the so-called Connectionist Temporal Classification loss function, these models can be directly trained from input images accompanied by their corresponding transcripts into music symbol sequences. We also present the Printed Music Scores dataset, containing more than 80,000 monodic single-staff real scores in common western notation, that is used to train and evaluate the neural approach. In our experiments, it is demonstrated that this formulation can be carried out successfully. Additionally, we study several considerations about the codification of the output musical sequences, the convergence and scalability of the neural models, as well as the ability of this approach to locate symbols in the input score.

  9. A Workflow-based Intelligent Network Data Movement Advisor with End-to-end Performance Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Michelle M. [Southern Illinois Univ., Carbondale, IL (United States); Wu, Chase Q. [Univ. of Memphis, TN (United States)

    2013-11-07

    Next-generation eScience applications often generate large amounts of simulation, experimental, or observational data that must be shared and managed by collaborative organizations. Advanced networking technologies and services have been rapidly developed and deployed to facilitate such massive data transfer. However, these technologies and services have not been fully utilized mainly because their use typically requires significant domain knowledge and in many cases application users are even not aware of their existence. By leveraging the functionalities of an existing Network-Aware Data Movement Advisor (NADMA) utility, we propose a new Workflow-based Intelligent Network Data Movement Advisor (WINDMA) with end-to-end performance optimization for this DOE funded project. This WINDMA system integrates three major components: resource discovery, data movement, and status monitoring, and supports the sharing of common data movement workflows through account and database management. This system provides a web interface and interacts with existing data/space management and discovery services such as Storage Resource Management, transport methods such as GridFTP and GlobusOnline, and network resource provisioning brokers such as ION and OSCARS. We demonstrate the efficacy of the proposed transport-support workflow system in several use cases based on its implementation and deployment in DOE wide-area networks.

  10. End to End Digitisation and Analysis of Three-Dimensional Coral Models, from Communities to Corallites.

    Directory of Open Access Journals (Sweden)

    Luis Gutierrez-Heredia

    Full Text Available Coral reefs hosts nearly 25% of all marine species and provide food sources for half a billion people worldwide while only a very small percentage have been surveyed. Advances in technology and processing along with affordable underwater cameras and Internet availability gives us the possibility to provide tools and softwares to survey entire coral reefs. Holistic ecological analyses of corals require not only the community view (10s to 100s of meters, but also the single colony analysis as well as corallite identification. As corals are three-dimensional, classical approaches to determine percent cover and structural complexity across spatial scales are inefficient, time-consuming and limited to experts. Here we propose an end-to-end approach to estimate these parameters using low-cost equipment (GoPro, Canon and freeware (123D Catch, Meshmixer and Netfabb, allowing every community to participate in surveys and monitoring of their coral ecosystem. We demonstrate our approach on 9 species of underwater colonies in ranging size and morphology. 3D models of underwater colonies, fresh samples and bleached skeletons with high quality texture mapping and detailed topographic morphology were produced, and Surface Area and Volume measurements (parameters widely used for ecological and coral health studies were calculated and analysed. Moreover, we integrated collected sample models with micro-photogrammetry models of individual corallites to aid identification and colony and polyp scale analysis.

  11. End to End Digitisation and Analysis of Three-Dimensional Coral Models, from Communities to Corallites.

    Science.gov (United States)

    Gutierrez-Heredia, Luis; Benzoni, Francesca; Murphy, Emma; Reynaud, Emmanuel G

    2016-01-01

    Coral reefs hosts nearly 25% of all marine species and provide food sources for half a billion people worldwide while only a very small percentage have been surveyed. Advances in technology and processing along with affordable underwater cameras and Internet availability gives us the possibility to provide tools and softwares to survey entire coral reefs. Holistic ecological analyses of corals require not only the community view (10s to 100s of meters), but also the single colony analysis as well as corallite identification. As corals are three-dimensional, classical approaches to determine percent cover and structural complexity across spatial scales are inefficient, time-consuming and limited to experts. Here we propose an end-to-end approach to estimate these parameters using low-cost equipment (GoPro, Canon) and freeware (123D Catch, Meshmixer and Netfabb), allowing every community to participate in surveys and monitoring of their coral ecosystem. We demonstrate our approach on 9 species of underwater colonies in ranging size and morphology. 3D models of underwater colonies, fresh samples and bleached skeletons with high quality texture mapping and detailed topographic morphology were produced, and Surface Area and Volume measurements (parameters widely used for ecological and coral health studies) were calculated and analysed. Moreover, we integrated collected sample models with micro-photogrammetry models of individual corallites to aid identification and colony and polyp scale analysis.

  12. Mechanics of spatulated end-to-end artery-to-vein anastomoses.

    Science.gov (United States)

    Morasch, M D; Dobrin, P B; Dong, Q S; Mrkvicka, R

    1998-01-01

    It previously has been shown that in straight end-to-end artery-to-vein anastomoses, maximum dimensions are obtained with an interrupted suture line. Nearly equivalent dimensions are obtained with a continuous compliant polybutester suture (Novafil), and the smallest dimensions are obtained with a continuous noncompliant polypropylene suture (Surgilene). The present study was undertaken to examine these suture techniques in a spatulated or beveled anastomosis in living dogs. Anastomoses were constructed using continuous 6-0 polypropylene (Surgilene), continuous 6-0 polybutester (Novafil), or interrupted 6-0 polypropylene or polybutester. Thirty minutes after construction, the artery, vein, and beveled anastomoses were excised, restored to in situ length and pressurized with the lumen filled with a dilute suspension of barium sulfate. High resolution radiographs were obtained at 25 mmHg pressure increments up to 200 mmHg. Dimensions and compliance were determined from the radiographic images. Results showed that, unlike straight artery-to-vein anastomoses, there were no differences in the dimensions or compliance of spatulated anastomoses with continuous Surgilene, continuous Novafil, or interrupted suture techniques. Therefore a continuous suture technique is acceptable when constructing spatulated artery-to-vein anastomoses in patients.

  13. Impacts of the Deepwater Horizon oil spill evaluated using an end-to-end ecosystem model.

    Science.gov (United States)

    Ainsworth, Cameron H; Paris, Claire B; Perlin, Natalie; Dornberger, Lindsey N; Patterson, William F; Chancellor, Emily; Murawski, Steve; Hollander, David; Daly, Kendra; Romero, Isabel C; Coleman, Felicia; Perryman, Holly

    2018-01-01

    We use a spatially explicit biogeochemical end-to-end ecosystem model, Atlantis, to simulate impacts from the Deepwater Horizon oil spill and subsequent recovery of fish guilds. Dose-response relationships with expected oil concentrations were utilized to estimate the impact on fish growth and mortality rates. We also examine the effects of fisheries closures and impacts on recruitment. We validate predictions of the model by comparing population trends and age structure before and after the oil spill with fisheries independent data. The model suggests that recruitment effects and fishery closures had little influence on biomass dynamics. However, at the assumed level of oil concentrations and toxicity, impacts on fish mortality and growth rates were large and commensurate with observations. Sensitivity analysis suggests the biomass of large reef fish decreased by 25% to 50% in areas most affected by the spill, and biomass of large demersal fish decreased even more, by 40% to 70%. Impacts on reef and demersal forage caused starvation mortality in predators and increased reliance on pelagic forage. Impacts on the food web translated effects of the spill far away from the oiled area. Effects on age structure suggest possible delayed impacts on fishery yields. Recovery of high-turnover populations generally is predicted to occur within 10 years, but some slower-growing populations may take 30+ years to fully recover.

  14. End-to-end Information Flow Security Model for Software-Defined Networks

    Directory of Open Access Journals (Sweden)

    D. Ju. Chaly

    2015-01-01

    Full Text Available Software-defined networks (SDN are a novel paradigm of networking which became an enabler technology for many modern applications such as network virtualization, policy-based access control and many others. Software can provide flexibility and fast-paced innovations in the networking; however, it has a complex nature. In this connection there is an increasing necessity of means for assuring its correctness and security. Abstract models for SDN can tackle these challenges. This paper addresses to confidentiality and some integrity properties of SDNs. These are critical properties for multi-tenant SDN environments, since the network management software must ensure that no confidential data of one tenant are leaked to other tenants in spite of using the same physical infrastructure. We define a notion of end-to-end security in context of software-defined networks and propose a semantic model where the reasoning is possible about confidentiality, and we can check that confidential information flows do not interfere with non-confidential ones. We show that the model can be extended in order to reason about networks with secure and insecure links which can arise, for example, in wireless environments.The article is published in the authors’ wording.

  15. Circumferential resection and "Z"-shape plastic end-to-end anastomosis of canine trachea.

    Science.gov (United States)

    Zhao, H; Li, Z; Fang, J; Fang, C

    1999-03-01

    To prevent anastomotic stricture of the trachea. Forty young mongrel dogs, weighing 5-7 kg, were randomly divided into two groups: experimental group and control group, with 20 dogs in each group. Four tracheal rings were removed from each dog. In the experimental group, two "Z"-shape tracheoplastic anastomoses were performed on each dog, one on the anterior wall and the other on the membranous part of the trachea. In the control group, each dog received only simple end-to-end anastomosis. Vicryl 3-0 absorbable suture and OB fibrin glue were used for both groups. All dogs were killed when their body weight doubled. The average sagittal stenotic ratio were 1.20 +/- 0.12 for the experimental group and 0.83 +/- 0.05 for the control group. The average cross-sectional area stenotic ratio were 0.90 +/- 0.12 and 0.69 +/- 0.09 and T values were 8.71 and 4.57 for the two groups (P anastomosis in preventing anastomotic stricture of canine trachea.

  16. Mucociliary clearance following tracheal resection and end-to-end anastomosis.

    Science.gov (United States)

    Toomes, H; Linder, A

    1989-10-01

    Mucociliary clearance is an important cleaning system of the bronchial tree. The complex transport system reacts sensitively to medicinal stimuli and inhaled substances. A disturbance causes secretion retention which encourages the development of acute and chronic pulmonary diseases. It is not yet known in which way sectional resection of the central airway effects mucociliary clearance. A large number of the surgical failures are attributable to septic complications in the area of the anastomosis. In order to study the transportation process over the anastomosis, ten dogs underwent a tracheal resection with end-to-end anastomosis, and the mucociliary activity was recorded using a bronchoscopic video-technical method. Recommencement of mucous transport was observed on the third, and transport over the anastomosis from the sixth to tenth, postoperative days. The mucociliary clearance had completely recovered on the twenty-first day in the majority of dogs. Histological examination of the anastomoses nine months postoperatively showed a flat substitute epithelium without cilia-bearing cells in all dogs. This contrasts with the quick restitution of the transport function. In case of undamaged respiratory mucosa, a good adaptation of the resection margins suffices for the mucous film to slide over the anastomosis.

  17. Human Assisted Robotic Vehicle Studies - A conceptual end-to-end mission architecture

    Science.gov (United States)

    Lehner, B. A. E.; Mazzotta, D. G.; Teeney, L.; Spina, F.; Filosa, A.; Pou, A. Canals; Schlechten, J.; Campbell, S.; Soriano, P. López

    2017-11-01

    With current space exploration roadmaps indicating the Moon as a proving ground on the way to human exploration of Mars, it is clear that human-robotic partnerships will play a key role for successful future human space missions. This paper details a conceptual end-to-end architecture for an exploration mission in cis-lunar space with a focus on human-robot interactions, called Human Assisted Robotic Vehicle Studies (HARVeSt). HARVeSt will build on knowledge of plant growth in space gained from experiments on-board the ISS and test the first growth of plants on the Moon. A planned deep space habitat will be utilised as the base of operations for human-robotic elements of the mission. The mission will serve as a technology demonstrator not only for autonomous tele-operations in cis-lunar space but also for key enabling technologies for future human surface missions. The successful approach of the ISS will be built on in this mission with international cooperation. Mission assets such as a modular rover will allow for an extendable mission and to scout and prepare the area for the start of an international Moon Village.

  18. Semantic Complex Event Processing over End-to-End Data Flows

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Qunzhi [University of Southern California; Simmhan, Yogesh; Prasanna, Viktor K.

    2012-04-01

    Emerging Complex Event Processing (CEP) applications in cyber physical systems like SmartPower Grids present novel challenges for end-to-end analysis over events, flowing from heterogeneous information sources to persistent knowledge repositories. CEP for these applications must support two distinctive features - easy specification patterns over diverse information streams, and integrated pattern detection over realtime and historical events. Existing work on CEP has been limited to relational query patterns, and engines that match events arriving after the query has been registered. We propose SCEPter, a semantic complex event processing framework which uniformly processes queries over continuous and archived events. SCEPteris built around an existing CEP engine with innovative support for semantic event pattern specification and allows their seamless detection over past, present and future events. Specifically, we describe a unified semantic query model that can operate over data flowing through event streams to event repositories. Compile-time and runtime semantic patterns are distinguished and addressed separately for efficiency. Query rewriting is examined and analyzed in the context of temporal boundaries that exist between event streams and their repository to avoid duplicate or missing results. The design and prototype implementation of SCEPterare analyzed using latency and throughput metrics for scenarios from the Smart Grid domain.

  19. An end-to-end assessment of range uncertainty in proton therapy using animal tissues

    Science.gov (United States)

    Zheng, Yuanshui; Kang, Yixiu; Zeidan, Omar; Schreuder, Niek

    2016-11-01

    Accurate assessment of range uncertainty is critical in proton therapy. However, there is a lack of data and consensus on how to evaluate the appropriate amount of uncertainty. The purpose of this study is to quantify the range uncertainty in various treatment conditions in proton therapy, using transmission measurements through various animal tissues. Animal tissues, including a pig head, beef steak, and lamb leg, were used in this study. For each tissue, an end-to-end test closely imitating patient treatments was performed. This included CT scan simulation, treatment planning, image-guided alignment, and beam delivery. Radio-chromic films were placed at various depths in the distal dose falloff region to measure depth dose. Comparisons between measured and calculated doses were used to evaluate range differences. The dose difference at the distal falloff between measurement and calculation depends on tissue type and treatment conditions. The estimated range difference was up to 5, 6 and 4 mm for the pig head, beef steak, and lamb leg irradiation, respectively. Our study shows that the TPS was able to calculate proton range within about 1.5% plus 1.5 mm. Accurate assessment of range uncertainty in treatment planning would allow better optimization of proton beam treatment, thus fully achieving proton beams’ superior dose advantage over conventional photon-based radiation therapy.

  20. Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process.

    Science.gov (United States)

    Ducray, C; Pommier, J P; Martins, L; Boussin, F D; Sabatier, L

    1999-07-22

    Loss of telomeric repeats during cell proliferation could play a role in senescence. It has been generally assumed that activation of telomerase prevents further telomere shortening and is essential for cell immortalization. In this study, we performed a detailed cytogenetic and molecular characterization of four SV40 transformed human fibroblastic cell lines by regularly monitoring the size distribution of terminal restriction fragments, telomerase activity and the associated chromosomal instability throughout immortalization. The mean TRF lengths progressively decreased in pre-crisis cells during the lifespan of the cultures. At crisis, telomeres reached a critical size, different among the cell lines, contributing to the peak of dicentric chromosomes, which resulted mostly from telomeric associations. We observed a direct correlation between short telomere length at crisis and chromosomal instability. In two immortal cell lines, although telomerase was detected, mean telomere length still continued to decrease whereas the number of dicentric chromosomes associated was stabilized. Thus telomerase could protect specifically telomeres which have reached a critical size against end-to-end dicentrics, while long telomeres continue to decrease, although at a slower rate as before crisis. This suggests a balance between elongation by telomerase and telomere shortening, towards a stabilized 'optimal' length.

  1. Practical End-to-End Performance Testing Tool for High Speed 3G-Based Networks

    Science.gov (United States)

    Shinbo, Hiroyuki; Tagami, Atsushi; Ano, Shigehiro; Hasegawa, Toru; Suzuki, Kenji

    High speed IP communication is a killer application for 3rd generation (3G) mobile systems. Thus 3G network operators should perform extensive tests to check whether expected end-to-end performances are provided to customers under various environments. An important objective of such tests is to check whether network nodes fulfill requirements to durations of processing packets because a long duration of such processing causes performance degradation. This requires testers (persons who do tests) to precisely know how long a packet is hold by various network nodes. Without any tool's help, this task is time-consuming and error prone. Thus we propose a multi-point packet header analysis tool which extracts and records packet headers with synchronized timestamps at multiple observation points. Such recorded packet headers enable testers to calculate such holding durations. The notable feature of this tool is that it is implemented on off-the shelf hardware platforms, i.e., lap-top personal computers. The key challenges of the implementation are precise clock synchronization without any special hardware and a sophisticated header extraction algorithm without any drop.

  2. An end-to-end microfluidic platform for engineering life supporting microbes in space exploration missions, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology proposes a programmable, low-cost, and compact microfluidic platform capable of running automated end-to-end processes and optimization...

  3. Design and end-to-end modelling of a deployable telescope

    Science.gov (United States)

    Dolkens, Dennis; Kuiper, Hans

    2017-09-01

    a closed-loop system based on measurements of the image sharpness as well as measurements obtained with edge sensors placed between the mirror segments. In addition, a phase diversity system will be used to recover residual wavefront aberrations. To aid the design of the deployable telescope, an end-to-end performance model was developed. The model is built around a dedicated ray-trace program written in Matlab. This program was built from the ground up for the purpose of modelling segmented telescope systems and allows for surface data computed with Finite Element Models (FEM) to be imported in the model. The program also contains modules which can simulate the closed-loop calibration of the telescope and it can use simulated images as an input for phase diversity and image processing algorithms. For a given thermo-mechanical state, the end-to-end model can predict the image quality that will be obtained after the calibration has been completed and the image has been processed. As such, the model is a powerful systems engineering tool, which can be used to optimize the in-orbit performance of a segmented, deployable telescope.

  4. SME2EM: Smart mobile end-to-end monitoring architecture for life-long diseases.

    Science.gov (United States)

    Serhani, Mohamed Adel; Menshawy, Mohamed El; Benharref, Abdelghani

    2016-01-01

    Monitoring life-long diseases requires continuous measurements and recording of physical vital signs. Most of these diseases are manifested through unexpected and non-uniform occurrences and behaviors. It is impractical to keep patients in hospitals, health-care institutions, or even at home for long periods of time. Monitoring solutions based on smartphones combined with mobile sensors and wireless communication technologies are a potential candidate to support complete mobility-freedom, not only for patients, but also for physicians. However, existing monitoring architectures based on smartphones and modern communication technologies are not suitable to address some challenging issues, such as intensive and big data, resource constraints, data integration, and context awareness in an integrated framework. This manuscript provides a novel mobile-based end-to-end architecture for live monitoring and visualization of life-long diseases. The proposed architecture provides smartness features to cope with continuous monitoring, data explosion, dynamic adaptation, unlimited mobility, and constrained devices resources. The integration of the architecture׳s components provides information about diseases׳ recurrences as soon as they occur to expedite taking necessary actions, and thus prevent severe consequences. Our architecture system is formally model-checked to automatically verify its correctness against designers׳ desirable properties at design time. Its components are fully implemented as Web services with respect to the SOA architecture to be easy to deploy and integrate, and supported by Cloud infrastructure and services to allow high scalability, availability of processes and data being stored and exchanged. The architecture׳s applicability is evaluated through concrete experimental scenarios on monitoring and visualizing states of epileptic diseases. The obtained theoretical and experimental results are very promising and efficiently satisfy the proposed

  5. jade: An End-To-End Data Transfer and Catalog Tool

    Science.gov (United States)

    Meade, P.

    2017-10-01

    The IceCube Neutrino Observatory is a cubic kilometer neutrino telescope located at the Geographic South Pole. IceCube collects 1 TB of data every day. An online filtering farm processes this data in real time and selects 10% to be sent via satellite to the main data center at the University of Wisconsin-Madison. IceCube has two year-round on-site operators. New operators are hired every year, due to the hard conditions of wintering at the South Pole. These operators are tasked with the daily operations of running a complex detector in serious isolation conditions. One of the systems they operate is the data archiving and transfer system. Due to these challenging operational conditions, the data archive and transfer system must above all be simple and robust. It must also share the limited resource of satellite bandwidth, and collect and preserve useful metadata. The original data archive and transfer software for IceCube was written in 2005. After running in production for several years, the decision was taken to fully rewrite it, in order to address a number of structural drawbacks. The new data archive and transfer software (JADE2) has been in production for several months providing improved performance and resiliency. One of the main goals for JADE2 is to provide a unified system that handles the IceCube data end-to-end: from collection at the South Pole, all the way to long-term archive and preservation in dedicated repositories at the North. In this contribution, we describe our experiences and lessons learned from developing and operating the data archive and transfer software for a particle physics experiment in extreme operational conditions like IceCube.

  6. In vivo laser assisted end-to-end anastomosis with ICG-infused chitosan patches

    Science.gov (United States)

    Rossi, Francesca; Matteini, Paolo; Esposito, Giuseppe; Scerrati, Alba; Albanese, Alessio; Puca, Alfredo; Maira, Giulio; Rossi, Giacomo; Pini, Roberto

    2011-07-01

    Laser assisted vascular repair is a new optimized technique based on the use of ICG-infused chitosan patch to close a vessel wound, with or even without few supporting single stitches. We present an in vivo experimental study on an innovative end-to-end laser assisted vascular anastomotic (LAVA) technique, performed with the application of ICGinfused chitosan patches. The photostability and the mechanical properties of ICG-infused chitosan films were preliminary measured. The in vivo study was performed in 10 New Zealand rabbits. After anesthesia, a 3-cm segment of the right common carotid artery was exposed, thus clamped proximally and distally. The artery was then interrupted by means of a full thickness cut. Three single microsutures were used to approximate the two vessel edges. The ICG-infused chitosan patch was rolled all over the anastomotic site and welded by the use of a diode laser emitting at 810 nm and equipped with a 300 μm diameter optical fiber. Welding was obtained by delivering single laser spots to induce local patch/tissue adhesion. The result was an immediate closure of the anastomosis, with no bleeding at clamps release. Thus animals underwent different follow-up periods, in order to evaluate the welded vessels over time. At follow-up examinations, all the anastomoses were patent and no bleeding signs were documented. Samples of welded vessels underwent histological examinations. Results showed that this technique offer several advantages over conventional suturing methods: simplification of the surgical procedure, shortening of the operative time, better re-endothelization and optimal vascular healing process.

  7. SPoRT - An End-to-End R2O Activity

    Science.gov (United States)

    Jedlovec, Gary J.

    2009-01-01

    Established in 2002 to demonstrate the weather and forecasting application of real-time EOS measurements, the Short-term Prediction Research and Transition (SPoRT) program has grown to be an end-to-end research to operations activity focused on the use of advanced NASA modeling and data assimilation approaches, nowcasting techniques, and unique high-resolution multispectral observational data applications from EOS satellites to improve short-term weather forecasts on a regional and local scale. SPoRT currently partners with several universities and other government agencies for access to real-time data and products, and works collaboratively with them and operational end users at 13 WFOs to develop and test the new products and capabilities in a "test-bed" mode. The test-bed simulates key aspects of the operational environment without putting constraints on the forecaster workload. Products and capabilities which show utility in the test-bed environment are then transitioned experimentally into the operational environment for further evaluation and assessment. SPoRT focuses on a suite of data and products from MODIS, AMSR-E, and AIRS on the NASA Terra and Aqua satellites, and total lightning measurements from ground-based networks. Some of the observations are assimilated into or used with various versions of the WRF model to provide supplemental forecast guidance to operational end users. SPoRT is enhancing partnerships with NOAA / NESDIS for new product development and data access to exploit the remote sensing capabilities of instruments on the NPOESS satellites to address short term weather forecasting problems. The VIIRS and CrIS instruments on the NPP and follow-on NPOESS satellites provide similar observing capabilities to the MODIS and AIRS instruments on Terra and Aqua. SPoRT will be transitioning existing and new capabilities into the AWIIPS II environment to continue the continuity of its activities.

  8. The CAT-ACT Beamline at ANKA: A new high energy X-ray spectroscopy facility for CATalysis and ACTinide research

    Science.gov (United States)

    Zimina, A.; Dardenne, K.; Denecke, M. A.; Grunwaldt, J. D.; Huttel, E.; Lichtenberg, H.; Mangold, S.; Pruessmann, T.; Rothe, J.; Steininger, R.; Vitova, T.

    2016-05-01

    A new hard X-ray beamline for CATalysis and ACTinide research has been built at the synchrotron radiation facility ANKA. The beamline design is dedicated to X-ray spectroscopy, including ‘flux hungry’ photon-in/photon-out and correlative techniques with a special infrastructure for radionuclide and catalysis research. The CAT-ACT beamline will help serve the growing need for high flux/hard X-ray spectroscopy in these communities. The design, the first spectra and the current status of this project are reported.

  9. Urban Biomining Meets Printable Electronics: End-To-End at Destination Biological Recycling and Reprinting

    Science.gov (United States)

    Rothschild, Lynn J. (Principal Investigator); Koehne, Jessica; Gandhiraman, Ram; Navarrete, Jesica; Spangle, Dylan

    2017-01-01

    Space missions rely utterly on metallic components, from the spacecraft to electronics. Yet, metals add mass, and electronics have the additional problem of a limited lifespan. Thus, current mission architectures must compensate for replacement. In space, spent electronics are discarded; on earth, there is some recycling but current processes are toxic and environmentally hazardous. Imagine instead an end-to-end recycling of spent electronics at low mass, low cost, room temperature, and in a non-toxic manner. Here, we propose a solution that will not only enhance mission success by decreasing upmass and providing a fresh supply of electronics, but in addition has immediate applications to a serious environmental issue on the Earth. Spent electronics will be used as feedstock to make fresh electronic components, a process we will accomplish with so-called 'urban biomining' using synthetically enhanced microbes to bind metals with elemental specificity. To create new electronics, the microbes will be used as 'bioink' to print a new IC chip, using plasma jet electronics printing. The plasma jet electronics printing technology will have the potential to use martian atmospheric gas to print and to tailor the electronic and chemical properties of the materials. Our preliminary results have suggested that this process also serves as a purification step to enhance the proportion of metals in the 'bioink'. The presence of electric field and plasma can ensure printing in microgravity environment while also providing material morphology and electronic structure tunabiity and thus optimization. Here we propose to increase the TRL level of the concept by engineering microbes to dissolve the siliceous matrix in the IC, extract copper from a mixture of metals, and use the microbes as feedstock to print interconnects using mars gas simulant. To assess the ability of this concept to influence mission architecture, we will do an analysis of the infrastructure required to execute

  10. IDENTIFYING ELUSIVE ELECTROMAGNETIC COUNTERPARTS TO GRAVITATIONAL WAVE MERGERS: AN END-TO-END SIMULATION

    International Nuclear Information System (INIS)

    Nissanke, Samaya; Georgieva, Alexandra; Kasliwal, Mansi

    2013-01-01

    Combined gravitational wave (GW) and electromagnetic (EM) observations of compact binary mergers should enable detailed studies of astrophysical processes in the strong-field gravity regime. This decade, ground-based GW interferometers promise to routinely detect compact binary mergers. Unfortunately, networks of GW interferometers have poor angular resolution on the sky and their EM signatures are predicted to be faint. Therefore, a challenging goal will be to unambiguously pinpoint the EM counterparts of GW mergers. We perform the first comprehensive end-to-end simulation that focuses on: (1) GW sky localization, distance measures, and volume errors with two compact binary populations and four different GW networks; (2) subsequent EM detectability by a slew of multiwavelength telescopes; and (3) final identification of the merger counterpart amidst a sea of possible astrophysical false positives. First, we find that double neutron star binary mergers can be detected out to a maximum distance of 400 Mpc (or 750 Mpc) by three (or five) detector GW networks, respectively. Neutron-star-black-hole binary mergers can be detected a factor of 1.5 further out; their median to maximum sky localizations are 50-170 deg 2 (or 6-65 deg 2 ) for a three (or five) detector GW network. Second, by optimizing depth, cadence, and sky area, we quantify relative fractions of optical counterparts that are detectable by a suite of different aperture-size telescopes across the globe. Third, we present five case studies to illustrate the diversity of scenarios in secure identification of the EM counterpart. We discuss the case of a typical binary, neither beamed nor nearby, and the challenges associated with identifying an EM counterpart at both low and high Galactic latitudes. For the first time, we demonstrate how construction of low-latency GW volumes in conjunction with local universe galaxy catalogs can help solve the problem of false positives. We conclude with strategies that would

  11. End-To-END Performance of the future MOMA intrument aboard the EXOMARS MISSION

    Science.gov (United States)

    Buch, A.; Pinnick, V. T.; Szopa, C.; Grand, N.; Danell, R.; van Amerom, F. H. W.; Freissinet, C.; Glavin, D. P.; Stalport, F.; Arevalo, R. D., Jr.; Coll, P. J.; Steininger, H.; Raulin, F.; Goesmann, F.; Mahaffy, P. R.; Brinckerhoff, W. B.

    2016-12-01

    After the SAM experiment aboard the curiosity rover, the Mars Organic Molecule Analyzer (MOMA) experiment aboard the future ExoMars mission will be the continuation of the search for the organic composition of the Mars surface with the advantage that the sample will be extracted as deep as 2 meters below the martian surface to minimize effects of radiation and oxidation on organic materials. To analyse the wide range of organic composition (volatile and non volatils compounds) of the martian soil MOMA is composed with an UV laser desorption / ionization (LDI) and a pyrolysis gas chromatography ion trap mass spectrometry (pyr-GC-ITMS). In order to analyse refractory organic compounds and chirality samples which undergo GC-ITMS analysis may be submitted to a derivatization process, consisting of the reaction of the sample components with specific reactants (MTBSTFA [1], DMF-DMA [2] or TMAH [3]). To optimize and test the performance of the GC-ITMS instrument we have performed several coupling tests campaigns between the GC, providing by the French team (LISA, LATMOS, CentraleSupelec), and the MS, providing by the US team (NASA, GSFC). Last campaign has been done with the ITU models wich is similar to the flight model and wich include the oven and the taping station providing by the German team (MPS). The results obtained demonstrate the current status of the end-to-end performance of the gas chromatography-mass spectrometry mode of operation. References:[1] Buch, A. et al. (2009) J chrom. A, 43, 143-151. [2] Freissinet et al. (2011) J Chrom A, 1306, 59-71. [3] Geffroy-Rodier, C. et al. (2009) JAAP, 85, 454-459. Acknowledgements: Funding provided by the Mars Exploration Program (point of contact, George Tahu, NASA/HQ). MOMA is a collaboration between NASA and ESA (PI Goesmann, MPS). MOMA-GC team acknowledges support from the French Space Agency (CNES), French National Programme of Planetology (PNP), National French Council (CNRS), Pierre Simon Laplace Institute.

  12. End-to-End Trade-space Analysis for Designing Constellation Missions

    Science.gov (United States)

    LeMoigne, J.; Dabney, P.; Foreman, V.; Grogan, P.; Hache, S.; Holland, M. P.; Hughes, S. P.; Nag, S.; Siddiqi, A.

    2017-12-01

    cost model represents an aggregate model consisting of Cost Estimating Relationships (CERs) from widely accepted models. The current GUI automatically generates graphics representing metrics such as average revisit time or coverage as a function of cost. The end-to-end system will be demonstrated as part of the presentation.

  13. An End-to-End System to Enable Quick, Easy and Inexpensive Deployment of Hydrometeorological Stations

    Science.gov (United States)

    Celicourt, P.; Piasecki, M.

    2014-12-01

    The high cost of hydro-meteorological data acquisition, communication and publication systems along with limited qualified human resources is considered as the main reason why hydro-meteorological data collection remains a challenge especially in developing countries. Despite significant advances in sensor network technologies which gave birth to open hardware and software, low-cost (less than $50) and low-power (in the order of a few miliWatts) sensor platforms in the last two decades, sensors and sensor network deployment remains a labor-intensive, time consuming, cumbersome, and thus expensive task. These factors give rise for the need to develop a affordable, simple to deploy, scalable and self-organizing end-to-end (from sensor to publication) system suitable for deployment in such countries. The design of the envisioned system will consist of a few Sensed-And-Programmed Arduino-based sensor nodes with low-cost sensors measuring parameters relevant to hydrological processes and a Raspberry Pi micro-computer hosting the in-the-field back-end data management. This latter comprises the Python/Django model of the CUAHSI Observations Data Model (ODM) namely DjangODM backed by a PostgreSQL Database Server. We are also developing a Python-based data processing script which will be paired with the data autoloading capability of Django to populate the DjangODM database with the incoming data. To publish the data, the WOFpy (WaterOneFlow Web Services in Python) developed by the Texas Water Development Board for 'Water Data for Texas' which can produce WaterML web services from a variety of back-end database installations such as SQLite, MySQL, and PostgreSQL will be used. A step further would be the development of an appealing online visualization tool using Python statistics and analytics tools (Scipy, Numpy, Pandas) showing the spatial distribution of variables across an entire watershed as a time variant layer on top of a basemap.

  14. The time-resolved and extreme conditions XAS (TEXAS) facility at the European Synchrotron Radiation Facility: the general-purpose EXAFS bending-magnet beamline BM23

    Energy Technology Data Exchange (ETDEWEB)

    Mathon, O., E-mail: mathon@esrf.fr; Beteva, A.; Borrel, J.; Bugnazet, D.; Gatla, S.; Hino, R.; Kantor, I.; Mairs, T. [European Synchrotron Radiation Facility, CS 40220, 38043 Grenoble Cedex 9 (France); Munoz, M. [European Synchrotron Radiation Facility, CS 40220, 38043 Grenoble Cedex 9 (France); Université Joseph Fourier, 1381 rue de la Piscine, BP 53, 38041 Grenoble Cedex 9 (France); Pasternak, S.; Perrin, F.; Pascarelli, S. [European Synchrotron Radiation Facility, CS 40220, 38043 Grenoble Cedex 9 (France)

    2015-10-17

    BM23 is the general-purpose EXAFS bending-magnet beamline at the ESRF, replacing the former BM29 beamline in the framework of the ESRF upgrade. Its mission is to serve the whole XAS user community by providing access to a basic service in addition to the many specialized instruments available at the ESRF. BM23 offers high-signal-to-noise ratio EXAFS in a large energy range (5–75 keV), continuous energy scanning for quick-EXAFS on the second timescale and a micro-XAS station delivering a spot size of 4 µm × 4 µm FWHM. BM23 is the general-purpose EXAFS bending-magnet beamline at the ESRF, replacing the former BM29 beamline in the framework of the ESRF upgrade. Its mission is to serve the whole XAS user community by providing access to a basic service in addition to the many specialized instruments available at the ESRF. BM23 offers high signal-to-noise ratio EXAFS in a large energy range (5–75 keV), continuous energy scanning for quick-EXAFS on the second timescale and a micro-XAS station delivering a spot size of 4 µm × 4 µm FWHM. It is a user-friendly facility featuring a high degree of automation, online EXAFS data reduction and a flexible sample environment.

  15. Computational Analysis Supporting the Design of a New Beamline for the Mines Neutron Radiography Facility

    Science.gov (United States)

    Wilson, C.; King, J.

    The Colorado School of Mines installed a neutron radiography system at the United States Geological Survey TRIGA reactor in 2012. An upgraded beamline could dramatically improve the imaging capabilities of this system. This project performed computational analyses to support the design of a new beamline, with the major goals of minimizing beam divergence and maximizing beam intensity. The new beamline will consist of a square aluminum tube with an 11.43 cm (4.5 in) inner side length and 0.635 cm (0.25 in) thick walls. It is the same length as the original beam tube (8.53 m) and is composed of 1.22 m (4 ft) and 1.52 m (5 ft) flanged sections which bolt together. The bottom 1.22 m of the beamline is a cylindrical aluminum pre-collimator which is 0.635 cm (0.25 in) thick, with an inner diameter of 5.08 cm (2 in). Based on Monte Carlo model results, when a pre-collimator is present, the use of a neutron absorbing liner on the inside surface of the beam tube has almost no effect on the angular distribution of the neutron current at the collimator exit. The use of a pre-collimator may result in a non-uniform flux profile at the image plane; however, as long as the collimator is at least three times longer than the pre-collimator, the flux distortion is acceptably low.

  16. Augmentation of Quick-EXAFS measurement facility at the energy scanning EXAFS beamline at INDUS-2 SRS

    Energy Technology Data Exchange (ETDEWEB)

    Poswal, A. K., E-mail: poswalashwini@gmail.com; Agrawal, Ankur; Bhattachryya, D.; Jha, S. N.; Sahoo, N. K. [Atomic and Molecular Physics Division, Bhabha Atomic Research Centre, Mumbai -400085 (India)

    2015-06-24

    In this paper implementation of Quick-EXAFS data acquisition facility at the Energy Scanning EXAFS beamline(BL-09) at INDUS-2 synchrotron source, Indore is presented. By adopting a continuous-scan mode in the Double Crystal monochromator (DCM), a high signal-to-noise ratio is maintained and the acquisition time is reduced to few seconds. The quality of spectra and repeatability is checked by measuring standards. The present mode of data acquisition would enable EXAFS measurement for in-situ studies even in fluorescence mode.

  17. Unidata's Vision for Providing Comprehensive and End-to-end Data Services

    Science.gov (United States)

    Ramamurthy, M. K.

    2009-05-01

    This paper presents Unidata's vision for providing comprehensive, well-integrated, and end-to-end data services for the geosciences. These include an array of functions for collecting, finding, and accessing data; data management tools for generating, cataloging, and exchanging metadata; and submitting or publishing, sharing, analyzing, visualizing, and integrating data. When this vision is realized, users no matter where they are or how they are connected to the Internetwill be able to find and access a plethora of geosciences data and use Unidata-provided tools and services both productively and creatively in their research and education. What that vision means for the Unidata community is elucidated by drawing a simple analogy. Most of users are familiar with Amazon and eBay e-commerce sites and content sharing sites like YouTube and Flickr. On the eBay marketplace, people can sell practically anything at any time and buyers can share their experience of purchasing a product or the reputation of a seller. Likewise, at Amazon, thousands of merchants sell their goods and millions of customers not only buy those goods, but provide a review or opinion of the products they buy and share their experiences as purchasers. Similarly, YouTube and Flickr are sites tailored to video- and photo-sharing, respectively, where users can upload their own content and share it with millions of other users, including family and friends. What all these sites, together with social-networking applications like MySpace and Facebook, have enabled is a sense of a virtual community in which users can search and browse products or content, comment and rate those products from anywhere, at any time, and via any Internet- enabled device like an iPhone, laptop, or a desktop computer. In essence, these enterprises have fundamentally altered people's buying modes and behavior toward purchases. Unidata believes that similar approaches, appropriately tailored to meet the needs of the scientific

  18. Ocean Acidification Scientific Data Stewardship: An approach for end-to-end data management and integration

    Science.gov (United States)

    Arzayus, K. M.; Garcia, H. E.; Jiang, L.; Michael, P.

    2012-12-01

    As the designated Federal permanent oceanographic data center in the United States, NOAA's National Oceanographic Data Center (NODC) has been providing scientific stewardship for national and international marine environmental and ecosystem data for over 50 years. NODC is supporting NOAA's Ocean Acidification Program and the science community by providing end-to-end scientific data management of ocean acidification (OA) data, dedicated online data discovery, and user-friendly access to a diverse range of historical and modern OA and other chemical, physical, and biological oceanographic data. This effort is being catalyzed by the NOAA Ocean Acidification Program, but the intended reach is for the broader scientific ocean acidification community. The first three years of the project will be focused on infrastructure building. A complete ocean acidification data content standard is being developed to ensure that a full spectrum of ocean acidification data and metadata can be stored and utilized for optimal data discovery and access in usable data formats. We plan to develop a data access interface capable of allowing users to constrain their search based on real-time and delayed mode measured variables, scientific data quality, their observation types, the temporal coverage, methods, instruments, standards, collecting institutions, and the spatial coverage. In addition, NODC seeks to utilize the existing suite of international standards (including ISO 19115-2 and CF-compliant netCDF) to help our data producers use those standards for their data, and help our data consumers make use of the well-standardized metadata-rich data sets. These tools will be available through our NODC Ocean Acidification Scientific Data Stewardship (OADS) web page at http://www.nodc.noaa.gov/oceanacidification. NODC also has a goal to provide each archived dataset with a unique ID, to ensure a means of providing credit to the data provider. Working with partner institutions, such as the

  19. Common Patterns with End-to-end Interoperability for Data Access

    Science.gov (United States)

    Gallagher, J.; Potter, N.; Jones, M. B.

    2010-12-01

    At first glance, using common storage formats and open standards should be enough to ensure interoperability between data servers and client applications, but that is often not the case. In the REAP (Realtime Environment for Analytical Processing; NSF #0619060) project we integrated access to data from OPeNDAP servers into the Kepler workflow system and found that, as in previous cases, we spent the bulk of our effort addressing the twin issues of data model compatibility and integration strategies. Implementing seamless data access between a remote data source and a client application (data sink) can be broken down into two kinds of issues. First, the solution must address any differences in the data models used by the data source (OPeNDAP) and the data sink (the Kepler workflow system). If these models match completely, there is little work to be done. However, that is rarely the case. To map OPeNDAP's data model to Kepler's, we used two techniques (ignoring trivial conversions): On-the-fly type mapping and out-of-band communication. Type conversion takes place both for data and metadata because Kepler requires a priori knowledge of some aspects (e.g., syntactic metadata) of the data to build a workflow. In addition, OPeNDAP's constraint expression syntax was used to send out-of-band information to restrict the data requested from the server, facilitating changes in the returned data's type. This technique provides a way for users to exert fine-grained control over the data request, a potentially useful technique, at the cost of requiring that users understand a little about the data source's processing capabilities. The second set of issues for end-to-end data access are integration strategies. OPeNDAP provides several different tools for bringing data into an application: C++, C and Java libraries that provide functions for newly written software; The netCDF library which enables existing applications to read from servers using an older interface; and simple

  20. On the importance of risk knowledge for an end-to-end tsunami early warning system

    Science.gov (United States)

    Post, Joachim; Strunz, Günter; Riedlinger, Torsten; Mück, Matthias; Wegscheider, Stephanie; Zosseder, Kai; Steinmetz, Tilmann; Gebert, Niklas; Anwar, Herryal

    2010-05-01

    context has been worked out. The generated results contribute significantly in the fields of (1) warning decision and warning levels, (2) warning dissemination and warning message content, (3) early warning chain planning, (4) increasing response capabilities and protective systems, (5) emergency relief and (6) enhancing communities' awareness and preparedness towards tsunami threats. Additionally examples will be given on the potentials of an operational use of risk information in early warning systems as first experiences exist for the tsunami early warning center in Jakarta, Indonesia. Beside this the importance of linking national level early warning information with tsunami risk information available at the local level (e.g. linking warning message information on expected intensity with respective tsunami hazard zone maps at community level for effective evacuation) will be demonstrated through experiences gained in three pilot areas in Indonesia. The presentation seeks to provide new insights on benefits using risk information in early warning and will provide further evidence that practical use of risk information is an important and indispensable component of end-to-end early warning.

  1. In-vacuum sensors for the beamline components of the ITER neutral beam test facility

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Palma, M., E-mail: mauro.dallapalma@igi.cnr.it; Pasqualotto, R.; Spagnolo, S.; Spolaore, M. [Consorzio RFX, Padova 35127 (Italy); Sartori, E. [Consorzio RFX, Padova 35127 (Italy); Università degli Studi di Padova, Padova 35122 (Italy); Veltri, P. [Consorzio RFX, Padova 35127 (Italy); INFN-LNL, Legnaro (PD) 35020 (Italy)

    2016-11-15

    Embedded sensors have been designed for installation on the components of the MITICA beamline, the prototype ITER neutral beam injector (Megavolt ITER Injector and Concept Advancement), to derive characteristics of the particle beam and to monitor the component conditions during operation for protection and thermal control. Along the beamline, the components interacting with the particle beam are the neutralizer, the residual ion dump, and the calorimeter. The design and the positioning of sensors on each component have been developed considering the expected beam-surface interaction including non-ideal and off-normal conditions. The arrangement of the following instrumentation is presented: thermal sensors, strain gages, electrostatic probes including secondary emission detectors, grounding shunt for electrical currents, and accelerometers.

  2. Beamlines at synchrotron radiation facilities: The link between the user and the machine

    International Nuclear Information System (INIS)

    Johnson, E.D.; Hulbert, S.L.; Berman, L.E.

    1991-12-01

    At this point in time the literature is full of excellent review articles which describe the operating principles of optical systems for utilizing the unique radiation provided by synchrotron storage rings. In general, the perspective provided by this body of work is that of the end user-experimenter cum optics designer. Nominal design specifications of the accelerator are usually assumed, and the impact of operation in a performance envelope which may represent either degraded or enhanced machine performance is seldom considered. In this article, we have attempted to remove ourselves from this (our own usual) perspective and look instead at the beamline as a transfer function to map from the machine to the users experiment. We open first with an introduction to the perspective of the experimentalist, and some general considerations for the interaction of beamline hardware with the machine. We then discuss phase space representations of some common components of beamlines, and then treat some important classes of crystal and geometric optics in monochromators. We then close with a discussion of some of the common features of these optical systems, and the impact of the machine on user experiments

  3. The time-resolved and extreme conditions XAS (TEXAS) facility at the European Synchrotron Radiation Facility: the general-purpose EXAFS bending-magnet beamline BM23.

    Science.gov (United States)

    Mathon, O; Beteva, A; Borrel, J; Bugnazet, D; Gatla, S; Hino, R; Kantor, I; Mairs, T; Munoz, M; Pasternak, S; Perrin, F; Pascarelli, S

    2015-11-01

    BM23 is the general-purpose EXAFS bending-magnet beamline at the ESRF, replacing the former BM29 beamline in the framework of the ESRF upgrade. Its mission is to serve the whole XAS user community by providing access to a basic service in addition to the many specialized instruments available at the ESRF. BM23 offers high signal-to-noise ratio EXAFS in a large energy range (5-75 keV), continuous energy scanning for quick-EXAFS on the second timescale and a micro-XAS station delivering a spot size of 4 µm × 4 µm FWHM. It is a user-friendly facility featuring a high degree of automation, online EXAFS data reduction and a flexible sample environment.

  4. A vision for end-to-end data services to foster international partnerships through data sharing

    Science.gov (United States)

    Ramamurthy, M.; Yoksas, T.

    2009-04-01

    Increasingly, the conduct of science requires scientific partnerships and sharing of knowledge, information, and other assets. This is particularly true in our field where the highly-coupled Earth system and its many linkages have heightened the importance of collaborations across geographic, disciplinary, and organizational boundaries. The climate system, for example, is far too complex a puzzle to be unraveled by individual investigators or nations. As articulated in the NSF Strategic Plan: FY 2006-2011, "…discovery increasingly requires expertise of individuals from different disciplines, with diverse perspectives, and often from different nations, working together to accommodate the extraordinary complexity of today's science and engineering challenges." The Nobel Prize winning IPCC assessments are a prime example of such an effort. Earth science education is also uniquely suited to drawing connections between the dynamic Earth system and societal issues. Events like the 2004 Indian Ocean tsunami and Hurricane Katrina provide ample evidence of this relevance, as they underscore the importance of timely and interdisciplinary integration and synthesis of data. Our success in addressing such complex problems and advancing geosciences depends on the availability of a state-of-the-art and robust cyberinfrastructure, transparent and timely access to high-quality data from diverse sources, and requisite tools to integrate and use the data effectively, toward creating new knowledge. To that end, Unidata's vision calls for providing comprehensive, well-integrated, and end-to-end data services for the geosciences. These include an array of functions for collecting, finding, and accessing data; data management tools for generating, cataloging, and exchanging metadata; and submitting or publishing, sharing, analyzing, visualizing, and integrating data. When this vision is realized, users — no matter where they are, how they are connected to the Internet, or what

  5. An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of ...

    African Journals Online (AJOL)

    An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of the southern Benguela foodweb: parameterisation, calibration and pattern-oriented validation. ... We also highlight the capacity of this model for tracking indicators at various hierarchical levels. Keywords: individual-based model, model validation, ...

  6. GROWTH OF THE HYPOPLASTIC AORTIC-ARCH AFTER SIMPLE COARCTATION RESECTION AND END-TO-END ANASTOMOSIS

    NARCIS (Netherlands)

    BROUWER, MHJ; CROMMEDIJKHUIS, AH; EBELS, T; EIJGELAAR, A

    Surgical treatment of a hypoplastic aortic arch associated with an aortic coarctation is controversial. The controversy concerns the claimed need to surgically enlarge the diameter of the hypoplastic arch, in addition to resection and end-to-end anastomosis. The purpose of this prospective study is

  7. Advanced Camera Image Cropping Approach for CNN-Based End-to-End Controls on Sustainable Computing

    Directory of Open Access Journals (Sweden)

    Yunsick Sung

    2018-03-01

    Full Text Available Recent research on deep learning has been applied to a diversity of fields. In particular, numerous studies have been conducted on self-driving vehicles using end-to-end approaches based on images captured by a single camera. End-to-end controls learn the output vectors of output devices directly from the input vectors of available input devices. In other words, an end-to-end approach learns not by analyzing the meaning of input vectors, but by extracting optimal output vectors based on input vectors. Generally, when end-to-end control is applied to self-driving vehicles, the steering wheel and pedals are controlled autonomously by learning from the images captured by a camera. However, high-resolution images captured from a car cannot be directly used as inputs to Convolutional Neural Networks (CNNs owing to memory limitations; the image size needs to be efficiently reduced. Therefore, it is necessary to extract features from captured images automatically and to generate input images by merging the parts of the images that contain the extracted features. This paper proposes a learning method for end-to-end control that generates input images for CNNs by extracting road parts from input images, identifying the edges of the extracted road parts, and merging the parts of the images that contain the detected edges. In addition, a CNN model for end-to-end control is introduced. Experiments involving the Open Racing Car Simulator (TORCS, a sustainable computing environment for cars, confirmed the effectiveness of the proposed method for self-driving by comparing the accumulated difference in the angle of the steering wheel in the images generated by it with those of resized images containing the entire captured area and cropped images containing only a part of the captured area. The results showed that the proposed method reduced the accumulated difference by 0.839% and 0.850% compared to those yielded by the resized images and cropped images

  8. The End-To-End Safety Verification Process Implemented to Ensure Safe Operations of the Columbus Research Module

    Science.gov (United States)

    Arndt, J.; Kreimer, J.

    2010-09-01

    The European Space Laboratory COLUMBUS was launched in February 2008 with NASA Space Shuttle Atlantis. Since successful docking and activation this manned laboratory forms part of the International Space Station(ISS). Depending on the objectives of the Mission Increments the on-orbit configuration of the COLUMBUS Module varies with each increment. This paper describes the end-to-end verification which has been implemented to ensure safe operations under the condition of a changing on-orbit configuration. That verification process has to cover not only the configuration changes as foreseen by the Mission Increment planning but also those configuration changes on short notice which become necessary due to near real-time requests initiated by crew or Flight Control, and changes - most challenging since unpredictable - due to on-orbit anomalies. Subject of the safety verification is on one hand the on orbit configuration itself including the hardware and software products, on the other hand the related Ground facilities needed for commanding of and communication to the on-orbit System. But also the operational products, e.g. the procedures prepared for crew and ground control in accordance to increment planning, are subject of the overall safety verification. In order to analyse the on-orbit configuration for potential hazards and to verify the implementation of the related Safety required hazard controls, a hierarchical approach is applied. The key element of the analytical safety integration of the whole COLUMBUS Payload Complement including hardware owned by International Partners is the Integrated Experiment Hazard Assessment(IEHA). The IEHA especially identifies those hazardous scenarios which could potentially arise through physical and operational interaction of experiments. A major challenge is the implementation of a Safety process which owns quite some rigidity in order to provide reliable verification of on-board Safety and which likewise provides enough

  9. End-to-end simulation of the C-ADS injector Ⅱ with a 3-D field map

    International Nuclear Information System (INIS)

    Wang Zhijun; He Yuan; Li Chao; Wang Wangsheng; Liu Shuhui; Jia Huan; Xu Xianbo; Chen Ximeng

    2013-01-01

    The Injector II, one of the two parallel injectors of the high-current superconducting proton driver linac for the China Accelerator-Driven System (C-ADS) project, is being designed and constructed by the Institute of Modern Physics. At present, the design work for the injector is almost finished. End-to-end simulation has been carried out using the TRACK multiparticle simulation code to check the match between each acceleration section and the performance of the injector as a whole. Moreover, multiparticle simulations with all kinds of errors and misalignments have been performed to define the requirements of each device. The simulation results indicate that the lattice design is robust. In this paper, the results of end-to-end simulation and error simulation with a 3-D field map are presented. (authors)

  10. Exploring the requirements for multimodal interaction for mobile devices in an end-to-end journey context.

    Science.gov (United States)

    Krehl, Claudia; Sharples, Sarah

    2012-01-01

    The paper investigates the requirements for multimodal interaction on mobile devices in an end-to-end journey context. Traditional interfaces are deemed cumbersome and inefficient for exchanging information with the user. Multimodal interaction provides a different user-centred approach allowing for more natural and intuitive interaction between humans and computers. It is especially suitable for mobile interaction as it can overcome additional constraints including small screens, awkward keypads, and continuously changing settings - an inherent property of mobility. This paper is based on end-to-end journeys where users encounter several contexts during their journeys. Interviews and focus groups explore the requirements for multimodal interaction design for mobile devices by examining journey stages and identifying the users' information needs and sources. Findings suggest that multimodal communication is crucial when users multitask. Choosing suitable modalities depend on user context, characteristics and tasks.

  11. Minimizing End-to-End Interference in I/O Stacks Spanning Shared Multi-Level Buffer Caches

    Science.gov (United States)

    Patrick, Christina M.

    2011-01-01

    This thesis presents an end-to-end interference minimizing uniquely designed high performance I/O stack that spans multi-level shared buffer cache hierarchies accessing shared I/O servers to deliver a seamless high performance I/O stack. In this thesis, I show that I can build a superior I/O stack which minimizes the inter-application interference…

  12. Sleep/wake scheduling scheme for minimizing end-to-end delay in multi-hop wireless sensor networks

    OpenAIRE

    Madani Sajjad; Nazir Babar; Hasbullah Halabi

    2011-01-01

    Abstract We present a sleep/wake schedule protocol for minimizing end-to-end delay for event driven multi-hop wireless sensor networks. In contrast to generic sleep/wake scheduling schemes, our proposed algorithm performs scheduling that is dependent on traffic loads. Nodes adapt their sleep/wake schedule based on traffic loads in response to three important factors, (a) the distance of the node from the sink node, (b) the importance of the node's location from connectivity's perspective, and...

  13. Multi-institutional evaluation of end-to-end protocol for IMRT/VMAT treatment chains utilizing conventional linacs.

    Science.gov (United States)

    Loughery, Brian; Knill, Cory; Silverstein, Evan; Zakjevskii, Viatcheslav; Masi, Kathryn; Covington, Elizabeth; Snyder, Karen; Song, Kwang; Snyder, Michael

    2018-03-20

    We conducted a multi-institutional assessment of a recently developed end-to-end monthly quality assurance (QA) protocol for external beam radiation therapy treatment chains. This protocol validates the entire treatment chain against a baseline to detect the presence of complex errors not easily found in standard component-based QA methods. Participating physicists from 3 institutions ran the end-to-end protocol on treatment chains that include Imaging and Radiation Oncology Core (IROC)-credentialed linacs. Results were analyzed in the form of American Association of Physicists in Medicine (AAPM) Task Group (TG)-119 so that they may be referenced by future test participants. Optically stimulated luminescent dosimeter (OSLD), EBT3 radiochromic film, and A1SL ion chamber readings were accumulated across 10 test runs. Confidence limits were calculated to determine where 95% of measurements should fall. From calculated confidence limits, 95% of measurements should be within 5% error for OSLDs, 4% error for ionization chambers, and 4% error for (96% relative gamma pass rate) radiochromic film at 3% agreement/3 mm distance to agreement. Data were separated by institution, model of linac, and treatment protocol (intensity-modulated radiation therapy [IMRT] vs volumetric modulated arc therapy [VMAT]). A total of 97% of OSLDs, 98% of ion chambers, and 93% of films were within the confidence limits; measurements were found outside these limits by a maximum of 4%, consistent despite institutional differences in OSLD reading equipment and radiochromic film calibration techniques. Results from this test may be used by clinics for data comparison. Areas of improvement were identified in the end-to-end protocol that can be implemented in an updated version. The consistency of our data demonstrates the reproducibility and ease-of-use of such tests and suggests a potential role for their use in broad end-to-end QA initiatives. Copyright © 2018 American Association of Medical

  14. Sleep/wake scheduling scheme for minimizing end-to-end delay in multi-hop wireless sensor networks

    Directory of Open Access Journals (Sweden)

    Madani Sajjad

    2011-01-01

    Full Text Available Abstract We present a sleep/wake schedule protocol for minimizing end-to-end delay for event driven multi-hop wireless sensor networks. In contrast to generic sleep/wake scheduling schemes, our proposed algorithm performs scheduling that is dependent on traffic loads. Nodes adapt their sleep/wake schedule based on traffic loads in response to three important factors, (a the distance of the node from the sink node, (b the importance of the node's location from connectivity's perspective, and (c if the node is in the proximity where an event occurs. Using these heuristics, the proposed scheme reduces end-to-end delay and maximizes the throughput by minimizing the congestion at nodes having heavy traffic load. Simulations are carried out to evaluate the performance of the proposed protocol, by comparing its performance with S-MAC and Anycast protocols. Simulation results demonstrate that the proposed protocol has significantly reduced the end-to-end delay, as well as has improved the other QoS parameters, like average energy per packet, average delay, packet loss ratio, throughput, and coverage lifetime.

  15. Hybrid monitoring scheme for end-to-end performance enhancement of multicast-based real-time media

    Science.gov (United States)

    Park, Ju-Won; Kim, JongWon

    2004-10-01

    As real-time media applications based on IP multicast networks spread widely, end-to-end QoS (quality of service) provisioning for these applications have become very important. To guarantee the end-to-end QoS of multi-party media applications, it is essential to monitor the time-varying status of both network metrics (i.e., delay, jitter and loss) and system metrics (i.e., CPU and memory utilization). In this paper, targeting the multicast-enabled AG (Access Grid) a next-generation group collaboration tool based on multi-party media services, the applicability of hybrid monitoring scheme that combines active and passive monitoring is investigated. The active monitoring measures network-layer metrics (i.e., network condition) with probe packets while the passive monitoring checks both application-layer metrics (i.e., user traffic condition by analyzing RTCP packets) and system metrics. By comparing these hybrid results, we attempt to pinpoint the causes of performance degradation and explore corresponding reactions to improve the end-to-end performance. The experimental results show that the proposed hybrid monitoring can provide useful information to coordinate the performance improvement of multi-party real-time media applications.

  16. Exploring Two Approaches for an End-to-End Scientific Analysis Workflow

    Science.gov (United States)

    Dodelson, Scott; Kent, Steve; Kowalkowski, Jim; Paterno, Marc; Sehrish, Saba

    2015-12-01

    The scientific discovery process can be advanced by the integration of independently-developed programs run on disparate computing facilities into coherent workflows usable by scientists who are not experts in computing. For such advancement, we need a system which scientists can use to formulate analysis workflows, to integrate new components to these workflows, and to execute different components on resources that are best suited to run those components. In addition, we need to monitor the status of the workflow as components get scheduled and executed, and to access the intermediate and final output for visual exploration and analysis. Finally, it is important for scientists to be able to share their workflows with collaborators. We have explored two approaches for such an analysis framework for the Large Synoptic Survey Telescope (LSST) Dark Energy Science Collaboration (DESC); the first one is based on the use and extension of Galaxy, a web-based portal for biomedical research, and the second one is based on a programming language, Python. In this paper, we present a brief description of the two approaches, describe the kinds of extensions to the Galaxy system we have found necessary in order to support the wide variety of scientific analysis in the cosmology community, and discuss how similar efforts might be of benefit to the HEP community.

  17. Radiation field characterization and shielding studies for the ELI Beamlines facility

    Czech Academy of Sciences Publication Activity Database

    Ferrari, A.; Amato, E.; Margarone, Daniele; Cowan, T.; Korn, Georg

    2013-01-01

    Roč. 272, May (2013), s. 138-144 ISSN 0169-4332 R&D Projects: GA MŠk ED1.1.00/02.0061; GA MŠk EE.2.3.20.0087; GA ČR(CZ) GAP205/11/1165 Grant - others:ELI Beamlines(XE) CZ.1.05/1.1.00/02.0061; OP VK 2 LaserGen(XE) CZ.1.07/2.3.00/20.0087; AVČR(CZ) M100101210 Institutional support: RVO:68378271 Keywords : particle acceleration from laser-matter interaction * shielding * Monte Carlo * radiation protection Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.538, year: 2013

  18. Induced radioactivity studies of the shielding and beamline equipment of the high intensity proton accelerator facility at PSI

    Directory of Open Access Journals (Sweden)

    Otiougova Polina

    2017-01-01

    Full Text Available The Paul Scherrer Institute (PSI is the largest national research center in Switzerland. Its multidisciplinary research is dedicated to a wide ↓eld in natural science and technology as well as particle physics. The High Intensity Proton Accelerator Facility (HIPA has been in operation at PSI since 1974. It includes an 870 keV Cockroft-Walton pre-accelerator, a 72 MeV injector cyclotron as well as a 590 MeV ring cyclotron. The experimental facilities, the meson production graphite targets, Target E and Target M, and the spallation target stations (SINQ and UCN are used for material research and particle physics. In order to ful↓ll the request of the regulatory authorities and to be reported to the regulators, the expected radioactive waste and nuclide inventory after an anticipated ↓nal shutdown in the far future has to be estimated. In this contribution, calculations for the 20 m long beamline between Target E and the 590 MeV beam dump of HIPA are presented. The ↓rst step in the calculations was determining spectra and spatial particle distributions around the beamlines using the Monte-Carlo particle transport code MCNPX2.7.0 [1]. To perform the analysis of the MCNPX output and to determine the radionuclide inventory as well as the speci↓c activity of the nuclides, an activation script [2] using the FISPACT10 code with the cross sections from the European Activation File (EAF2010 [3] was applied. The speci↓c activity values were compared to the currently existing Swiss exemption limits (LE [4] as well as to the Swiss liberation limits (LL [5], becoming e↑ective in the near future. The obtained results were used to estimate the total volume of the radioactive waste produced at HIPA and have to be reported to the Swiss regulatory authorities. The comparison of the performed calculations to measurements is discussed as well.

  19. Debris mitigation measures by satellite design and operational methods - Findings from the DLR space debris End-to-End Service

    Science.gov (United States)

    Sdunnus, H.; Beltrami, P.; Janovsky, R.; Koppenwallner, G.; Krag, H.; Reimerdes, H.; Schäfer, F.

    Debris Mitigation has been recognised as an issue to be addressed by the space faring nations around the world. Currently, there are various activities going on, aiming at the establishment of debris mitigation guidelines on various levels, reaching from the UN down to national space agencies. Though guidelines established on the national level already provide concrete information how things should be done (rather that specifying what should be done or providing fundamental principles) potential users of the guidelines will still have the need to explore the technical, management, and financial implications of the guidelines for their projects. Those questions are addressed by the so called "Space Debris End-to-End Service" project, which has been initiated as a national initiative of the German Aerospace Centre (DLR). Based on a review of already existing mitigation guidelines or guidelines under development and following an identification of needs from a circle of industrial users the "End-to-End Service Gu idelines" have been established for designer and operators of spacecraft. The End-to-End Service Guidelines are based on requirements addressed by the mitigation guidelines and provide recommendations how and when the technical consideration of the mitigation guidelines should take place. By referencing requirements from the mitigation guidelines, the End-to-End Service Guidelines address the consideration of debris mitigation measures by spacecraft design and operational measures. This paper will give an introduction to the End-to-End Service Guidelines. It will focus on the proposals made for mitigation measures by the S/C system design, i.e. on protective design measures inside the spacecraft and on design measures, e.g. innovative protective (shielding) systems. Furthermore, approaches on the analytical optimisation of protective systems will be presented, aiming at the minimisation of shield mass under conservation of the protective effects. On the

  20. Understanding Effect of Constraint Release Environment on End-to-End Vector Relaxation of Linear Polymer Chains

    KAUST Repository

    Shivokhin, Maksim E.

    2017-05-30

    We propose and verify methods based on the slip-spring (SSp) model [ Macromolecules 2005, 38, 14 ] for predicting the effect of any monodisperse, binary, or ternary environment of topological constraints on the relaxation of the end-to-end vector of a linear probe chain. For this purpose we first validate the ability of the model to consistently predict both the viscoelastic and dielectric response of monodisperse and binary mixtures of type A polymers, based on published experimental data. We also report the synthesis of new binary and ternary polybutadiene systems, the measurement of their linear viscoelastic response, and the prediction of these data by the SSp model. We next clarify the relaxation mechanisms of probe chains in these constraint release (CR) environments by analyzing a set of "toy" SSp models with simplified constraint release rates, by examining fluctuations of the end-to-end vector. In our analysis, the longest relaxation time of the probe chain is determined by a competition between the longest relaxation times of the effective CR motions of the fat and thin tubes and the motion of the chain itself in the thin tube. This picture is tested by the analysis of four model systems designed to separate and estimate every single contribution involved in the relaxation of the probe\\'s end-to-end vector in polydisperse systems. We follow the CR picture of Viovy et al. [ Macromolecules 1991, 24, 3587 ] and refine the effective chain friction in the thin and fat tubes based on Read et al. [ J. Rheol. 2012, 56, 823 ]. The derived analytical equations form a basis for generalizing the proposed methodology to polydisperse mixtures of linear and branched polymers. The consistency between the SSp model and tube model predictions is a strong indicator of the compatibility between these two distinct mesoscopic frameworks.

  1. Crosstalk in an FDM Laboratory Setup and the Athena X-IFU End-to-End Simulator

    Science.gov (United States)

    den Hartog, R.; Kirsch, C.; de Vries, C.; Akamatsu, H.; Dauser, T.; Peille, P.; Cucchetti, E.; Jackson, B.; Bandler, S.; Smith, S.; Wilms, J.

    2018-04-01

    The impact of various crosstalk mechanisms on the performance of the Athena X-IFU instrument has been assessed with detailed end-to-end simulations. For the crosstalk in the electrical circuit, a detailed model has been developed. In this contribution, we test this model against measurements made with an FDM laboratory setup and discuss the assumption of deterministic crosstalk in the context of the weak link effect in the detectors. We conclude that crosstalk levels predicted by the model are conservative with respect to the observed levels.

  2. Automated Design of Propellant-Optimal, End-to-End, Low-Thrust Trajectories for Trojan Asteroid Tours

    Science.gov (United States)

    Stuart, Jeffrey; Howell, Kathleen; Wilson, Roby

    2013-01-01

    The Sun-Jupiter Trojan asteroids are celestial bodies of great scientific interest as well as potential resources offering water and other mineral resources for longterm human exploration of the solar system. Previous investigations under this project have addressed the automated design of tours within the asteroid swarm. This investigation expands the current automation scheme by incorporating options for a complete trajectory design approach to the Trojan asteroids. Computational aspects of the design procedure are automated such that end-to-end trajectories are generated with a minimum of human interaction after key elements and constraints associated with a proposed mission concept are specified.

  3. AN AUTOMATED END-TO-END MULTI-AGENT QOS BASED ARCHITECTURE FOR SELECTION OF GEOSPATIAL WEB SERVICES

    Directory of Open Access Journals (Sweden)

    M. Shah

    2012-07-01

    With the proliferation of web services published over the internet, multiple web services may provide similar functionality, but with different non-functional properties. Thus, Quality of Service (QoS offers a metric to differentiate the services and their service providers. In a quality-driven selection of web services, it is important to consider non-functional properties of the web service so as to satisfy the constraints or requirements of the end users. The main intent of this paper is to build an automated end-to-end multi-agent based solution to provide the best-fit web service to service requester based on QoS.

  4. Comparison of Direct Side-to-End and End-to-End Hypoglossal-Facial Anastomosis for Facial Nerve Repair.

    Science.gov (United States)

    Samii, Madjid; Alimohamadi, Maysam; Khouzani, Reza Karimi; Rashid, Masoud Rafizadeh; Gerganov, Venelin

    2015-08-01

    The hypoglossal facial anastomosis (HFA) is the gold standard for facial reanimation in patients with severe facial nerve palsy. The major drawbacks of the classic HFA technique are lingual morbidities due to hypoglossal nerve transection. The side-to-end HFA is a modification of the classic technique with fewer tongue-related morbidities. In this study we compared the outcome of the classic end-to-end and the direct side-to-end HFA surgeries performed at our center in regards to the facial reanimation success rate and tongue-related morbidities. Twenty-six successive cases of HFA were enrolled. In 9 of them end-to-end anastomoses were performed, and 17 had direct side-to-end anastomoses. The House-Brackmann (HB) and Pitty and Tator (PT) scales were used to document surgical outcome. The hemiglossal atrophy, swallowing, and hypoglossal nerve function were assessed at follow-up. The original pathology was vestibular schwannoma in 15, meningioma in 4, brain stem glioma in 4, and other pathologies in 3. The mean interval between facial palsy and HFA was 18 months (range: 0-60). The median follow-up period was 20 months. The PT grade at follow-up was worse in patients with a longer interval from facial palsy and HFA (P value: 0.041). The lesion type was the only other factor that affected PT grade (the best results in vestibular schwannoma and the worst in the other pathologies group, P value: 0.038). The recovery period for facial tonicity was longer in patients with radiation therapy before HFA (13.5 vs. 8.5 months) and those with a longer than 2-year interval from facial palsy to HFA (13.5 vs. 8.5 months). Although no significant difference between the side-to-end and the end-to-end groups was seen in terms of facial nerve functional recovery, patients from the side-to-end group had a significantly lower rate of lingual morbidities (tongue hemiatrophy: 100% vs. 5.8%, swallowing difficulty: 55% vs. 11.7%, speech disorder 33% vs. 0%). With the side-to-end HFA

  5. Risk Factors for Dehiscence of Stapled Functional End-to-End Intestinal Anastomoses in Dogs: 53 Cases (2001-2012).

    Science.gov (United States)

    Snowdon, Kyle A; Smeak, Daniel D; Chiang, Sharon

    2016-01-01

    To identify risk factors for dehiscence in stapled functional end-to-end anastomoses (SFEEA) in dogs. Retrospective case series. Dogs (n = 53) requiring an enterectomy. Medical records from a single institution for all dogs undergoing an enterectomy (2001-2012) were reviewed. Surgeries were included when gastrointestinal (GIA) and thoracoabdominal (TA) stapling equipment was used to create a functional end-to-end anastomosis between segments of small intestine or small and large intestine in dogs. Information regarding preoperative, surgical, and postoperative factors was recorded. Anastomotic dehiscence was noted in 6 of 53 cases (11%), with a mortality rate of 83%. The only preoperative factor significantly associated with dehiscence was the presence of inflammatory bowel disease (IBD). Surgical factors significantly associated with dehiscence included the presence, duration, and number of intraoperative hypotensive periods, and location of anastomosis, with greater odds of dehiscence in anastomoses involving the large intestine. IBD, location of anastomosis, and intraoperative hypotension are risk factors for intestinal anastomotic dehiscence after SFEEA in dogs. Previously suggested risk factors (low serum albumin concentration, preoperative septic peritonitis, and intestinal foreign body) were not confirmed in this study. © Copyright 2015 by The American College of Veterinary Surgeons.

  6. A new technique for end-to-end ureterostomy in the rat, using an indwelling reabsorbable stent.

    Science.gov (United States)

    Carmignani, G; Farina, F P; De Stefani, S; Maffezzini, M

    1983-01-01

    The restoration of the continuity of the urinary tract represents one of the major problems in rat renal transplantation. End-to-end ureterostomy is the most physiologically effective technique; however, it involves noteworthy technical difficulties because of the extremely thin caliber of the ureter in the rat and the high incidence of postoperative hydronephrosis. We describe a new technique for end-to-end ureterostomy in the rat, where the use of an absorbable ureteral stent is recommended. A 5-0 plain catgut thread is used as a stent. The anastomosis is performed under an operating microscope at X 25-40 magnification with interrupted sutures of 11-0 Vicryl. The use of the indwelling stent facilitates the performance of the anastomosis and yields optimal results. The macroscopical, radiological, and histological controls in a group of rats operated on with this technique showed a very high percentage of success with no complications, a result undoubtedly superior to that obtained with conventional methods.

  7. A multicentre 'end to end' dosimetry audit of motion management (4DCT-defined motion envelope) in radiotherapy.

    Science.gov (United States)

    Palmer, Antony L; Nash, David; Kearton, John R; Jafari, Shakardokht M; Muscat, Sarah

    2017-12-01

    External dosimetry audit is valuable for the assurance of radiotherapy quality. However, motion management has not been rigorously audited, despite its complexity and importance for accuracy. We describe the first end-to-end dosimetry audit for non-SABR (stereotactic ablative body radiotherapy) lung treatments, measuring dose accumulation in a moving target, and assessing adequacy of target dose coverage. A respiratory motion lung-phantom with custom-designed insert was used. Dose was measured with radiochromic film, employing triple-channel dosimetry and uncertainty reduction. The host's 4DCT scan, outlining and planning techniques were used. Measurements with the phantom static and then moving at treatment delivery separated inherent treatment uncertainties from motion effects. Calculated and measured dose distributions were compared by isodose overlay, gamma analysis, and we introduce the concept of 'dose plane histograms' for clinically relevant interpretation of film dosimetry. 12 radiotherapy centres and 19 plans were audited: conformal, IMRT (intensity modulated radiotherapy) and VMAT (volumetric modulated radiotherapy). Excellent agreement between planned and static-phantom results were seen (mean gamma pass 98.7% at 3% 2 mm). Dose blurring was evident in the moving-phantom measurements (mean gamma pass 88.2% at 3% 2 mm). Planning techniques for motion management were adequate to deliver the intended moving-target dose coverage. A novel, clinically-relevant, end-to-end dosimetry audit of motion management strategies in radiotherapy is reported. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. End-to-end self-assembly of gold nanorods in isopropanol solution: experimental and theoretical studies

    Energy Technology Data Exchange (ETDEWEB)

    Gordel, M., E-mail: marta.gordel@pwr.edu.pl [Wrocław University of Technology, Advanced Materials Engineering and Modelling Group, Faculty of Chemistry (Poland); Piela, K., E-mail: katarzyna.piela@pwr.edu.pl [Wrocław University of Technology, Department of Physical and Quantum Chemistry (Poland); Kołkowski, R. [Wrocław University of Technology, Advanced Materials Engineering and Modelling Group, Faculty of Chemistry (Poland); Koźlecki, T. [Wrocław University of Technology, Department of Chemical Engineering, Faculty of Chemistry (Poland); Buckle, M. [CNRS, École Normale Supérieure de Cachan, Laboratoire de Biologie et Pharmacologie Appliquée (France); Samoć, M. [Wrocław University of Technology, Advanced Materials Engineering and Modelling Group, Faculty of Chemistry (Poland)

    2015-12-15

    We describe here a modification of properties of colloidal gold nanorods (NRs) resulting from the chemical treatment used to carry out their transfer into isopropanol (IPA) solution. The NRs acquire a tendency to attach one to another by their ends (end-to-end assembly). We focus on the investigation of the change in position and shape of the longitudinal surface plasmon (l-SPR) band after self-assembly. The experimental results are supported by a theoretical calculation, which rationalizes the dramatic change in optical properties when the NRs are positioned end-to-end at short distances. The detailed spectroscopic characterization performed at the consecutive stages of transfer of the NRs from water into IPA solution revealed the features of the interaction between the polymers used as ligands and their contribution to the final stage, when the NRs were dispersed in IPA solution. The efficient method of aligning the NRs detailed here may facilitate applications of the self-assembled NRs as building blocks for optical materials and biological sensing.Graphical Abstract.

  9. Analysis of the relationship between end-to-end distance and activity of single-chain antibody against colorectal carcinoma.

    Science.gov (United States)

    Zhang, Jianhua; Liu, Shanhong; Shang, Zhigang; Shi, Li; Yun, Jun

    2012-08-22

    We investigated the relationship of End-to-end distance between VH and VL with different peptide linkers and the activity of single-chain antibodies by computer-aided simulation. First, we developed (G4S)n (where n = 1-9) as the linker to connect VH and VL, and estimated the 3D structure of single-chain Fv antibody (scFv) by homologous modeling. After molecular models were evaluated and optimized, the coordinate system of every protein was built and unified into one coordinate system, and End-to-end distances calculated using 3D space coordinates. After expression and purification of scFv-n with (G4S)n as n = 1, 3, 5, 7 or 9, the immunoreactivity of purified ND-1 scFv-n was determined by ELISA. A multi-factorial relationship model was employed to analyze the structural factors affecting scFv: rn=ABn-ABO2+CDn-CDO2+BCn-BCst2. The relationship between immunoreactivity and r-values revealed that fusion protein structure approached the desired state when the r-value = 3. The immunoreactivity declined as the r-value increased, but when the r-value exceeded a certain threshold, it stabilized. We used a linear relationship to analyze structural factors affecting scFv immunoreactivity.

  10. End-to-End Joint Antenna Selection Strategy and Distributed Compress and Forward Strategy for Relay Channels

    Directory of Open Access Journals (Sweden)

    Rahul Vaze

    2009-01-01

    Full Text Available Multihop relay channels use multiple relay stages, each with multiple relay nodes, to facilitate communication between a source and destination. Previously, distributed space-time codes were proposed to maximize the achievable diversity-multiplexing tradeoff; however, they fail to achieve all the points of the optimal diversity-multiplexing tradeoff. In the presence of a low-rate feedback link from the destination to each relay stage and the source, this paper proposes an end-to-end antenna selection (EEAS strategy as an alternative to distributed space-time codes. The EEAS strategy uses a subset of antennas of each relay stage for transmission of the source signal to the destination with amplifying and forwarding at each relay stage. The subsets are chosen such that they maximize the end-to-end mutual information at the destination. The EEAS strategy achieves the corner points of the optimal diversity-multiplexing tradeoff (corresponding to maximum diversity gain and maximum multiplexing gain and achieves better diversity gain at intermediate values of multiplexing gain, versus the best-known distributed space-time coding strategies. A distributed compress and forward (CF strategy is also proposed to achieve all points of the optimal diversity-multiplexing tradeoff for a two-hop relay channel with multiple relay nodes.

  11. Weighted-DESYNC and Its Application to End-to-End Throughput Fairness in Wireless Multihop Network

    Directory of Open Access Journals (Sweden)

    Ui-Seong Yu

    2017-01-01

    Full Text Available The end-to-end throughput of a routing path in wireless multihop network is restricted by a bottleneck node that has the smallest bandwidth among the nodes on the routing path. In this study, we propose a method for resolving the bottleneck-node problem in multihop networks, which is based on multihop DESYNC (MH-DESYNC algorithm that is a bioinspired resource allocation method developed for use in multihop environments and enables fair resource allocation among nearby (up to two hops neighbors. Based on MH-DESYNC, we newly propose weighted-DESYNC (W-DESYNC as a tool artificially to control the amount of resource allocated to the specific user and thus to achieve throughput fairness over a routing path. Proposed W-DESYNC employs the weight factor of a link to determine the amount of bandwidth allocated to a node. By letting the weight factor be the link quality of a routing path and making it the same across a routing path via Cucker-Smale flocking model, we can obtain throughput fairness over a routing path. The simulation results show that the proposed algorithm achieves throughput fairness over a routing path and can increase total end-to-end throughput in wireless multihop networks.

  12. Induced radioactivity studies of the shielding and beamline equipment of the high intensity proton accelerator facility at PSI

    Science.gov (United States)

    Otiougova, Polina; Bergmann, Ryan; Kiselev, Daniela; Talanov, Vadim; Wohlmuther, Michael

    2017-09-01

    The Paul Scherrer Institute (PSI) is the largest national research center in Switzerland. Its multidisciplinary research is dedicated to a wide ↓eld in natural science and technology as well as particle physics. The High Intensity Proton Accelerator Facility (HIPA) has been in operation at PSI since 1974. It includes an 870 keV Cockroft-Walton pre-accelerator, a 72 MeV injector cyclotron as well as a 590 MeV ring cyclotron. The experimental facilities, the meson production graphite targets, Target E and Target M, and the spallation target stations (SINQ and UCN) are used for material research and particle physics. In order to ful↓ll the request of the regulatory authorities and to be reported to the regulators, the expected radioactive waste and nuclide inventory after an anticipated ↓nal shutdown in the far future has to be estimated. In this contribution, calculations for the 20 m long beamline between Target E and the 590 MeV beam dump of HIPA are presented. The ↓rst step in the calculations was determining spectra and spatial particle distributions around the beamlines using the Monte-Carlo particle transport code MCNPX2.7.0 [1]. To perform the analysis of the MCNPX output and to determine the radionuclide inventory as well as the speci↓c activity of the nuclides, an activation script [2] using the FISPACT10 code with the cross sections from the European Activation File (EAF2010) [3] was applied. The speci↓c activity values were compared to the currently existing Swiss exemption limits (LE) [4] as well as to the Swiss liberation limits (LL) [5], becoming e↑ective in the near future. The obtained results were used to estimate the total volume of the radioactive waste produced at HIPA and have to be reported to the Swiss regulatory authorities. The comparison of the performed calculations to measurements is discussed as well. Note to the reader: the pdf file has been changed on September 22, 2017.

  13. End-to-end Structural Restriction of α-Synuclein and Its Influence on Amyloid Fibril Formation

    International Nuclear Information System (INIS)

    Hong, Chul Suk; Park, Jae Hyung; Choe, Young Jun; Paik, Seung R.

    2014-01-01

    Relationship between molecular freedom of amyloidogenic protein and its self-assembly into amyloid fibrils has been evaluated with α-synuclein, an intrinsically unfolded protein related to Parkinson's disease, by restricting its structural plasticity through an end-to-end disulfide bond formation between two newly introduced cysteine residues on the N- and C-termini. Although the resulting circular form of α-synuclein exhibited an impaired fibrillation propensity, the restriction did not completely block the protein's interactive core since co-incubation with wild-type α-synuclein dramatically facilitated the fibrillation by producing distinctive forms of amyloid fibrils. The suppressed fibrillation propensity was instantly restored as the structural restriction was unleashed with β-mercaptoethanol. Conformational flexibility of the accreting amyloidogenic protein to pre-existing seeds has been demonstrated to be critical for fibrillar extension process by exerting structural adjustment to a complementary structure for the assembly

  14. End-to-end Structural Restriction of α-Synuclein and Its Influence on Amyloid Fibril Formation

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Chul Suk; Park, Jae Hyung; Choe, Young Jun; Paik, Seung R. [Seoul National University, Seoul (Korea, Republic of)

    2014-09-15

    Relationship between molecular freedom of amyloidogenic protein and its self-assembly into amyloid fibrils has been evaluated with α-synuclein, an intrinsically unfolded protein related to Parkinson's disease, by restricting its structural plasticity through an end-to-end disulfide bond formation between two newly introduced cysteine residues on the N- and C-termini. Although the resulting circular form of α-synuclein exhibited an impaired fibrillation propensity, the restriction did not completely block the protein's interactive core since co-incubation with wild-type α-synuclein dramatically facilitated the fibrillation by producing distinctive forms of amyloid fibrils. The suppressed fibrillation propensity was instantly restored as the structural restriction was unleashed with β-mercaptoethanol. Conformational flexibility of the accreting amyloidogenic protein to pre-existing seeds has been demonstrated to be critical for fibrillar extension process by exerting structural adjustment to a complementary structure for the assembly.

  15. Self-assembled nanogaps via seed-mediated growth of end-to-end linked gold nanorods

    DEFF Research Database (Denmark)

    Jain, Titoo; Westerlund, Axel Rune Fredrik; Johnson, Erik

    2009-01-01

    Gold nanorods (AuNRs) are of interest for a wide range of applications, ranging from imaging to molecular electronics, and they have been studied extensively for the past decade. An important issue in AuNR applications is the ability to self-assemble the rods in predictable structures...... on the nanoscale. We here present a new way to end-to-end link AuNRs with a single or few linker molecules. Whereas methods reported in the literature so far rely on modification of the AuNRs after the synthesis, we here dimerize gold nanoparticle seeds with a water-soluble dithiol-functionalized polyethylene...... that a large fraction of the rods are flexible around the hinging molecule in solution, as expected for a molecularly linked nanogap. By using excess of gold nanoparticles relative to the linking dithiol molecule, this method can provide a high probability that a single molecule is connecting the two rods...

  16. Increasing gas producer profitability with virtual well visibility via an end-to-end wireless Internet gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, M. [Northrock Resources Ltd., Calgary, AB (Canada); Benterud, K. [Zed.i solutions, Calgary, AB (Canada)

    2003-07-01

    This PowerPoint presentation describes how Northrock Resources Ltd. increased profitability using Smart-Alek{sup TM} while avoiding high implementation costs. Smart-Alek is a new type of fully integrated end-to-end electronic gas flow measurement (GFM) system based on Field Intelligence Network and End User Interference (FINE). Smart-Alek can analyze gas production through public wireless communications and a web-browser delivery system. The system has enabled Northrock to increase gas volumes with more accurate measurement and reduced downtime. In addition, operating costs have decreased because the frequency of well visits has been reduced and the administrative procedures of data collection is more efficient. The real-time well visibility of the tool has proven to be very effective in optimizing business profitability. 7 figs.

  17. End-to-End Trajectory for Conjunction Class Mars Missions Using Hybrid Solar-Electric/Chemical Transportation System

    Science.gov (United States)

    Chai, Patrick R.; Merrill, Raymond G.; Qu, Min

    2016-01-01

    NASA's Human Spaceflight Architecture Team is developing a reusable hybrid transportation architecture in which both chemical and solar-electric propulsion systems are used to deliver crew and cargo to exploration destinations. By combining chemical and solar-electric propulsion into a single spacecraft and applying each where it is most effective, the hybrid architecture enables a series of Mars trajectories that are more fuel efficient than an all chemical propulsion architecture without significant increases to trip time. The architecture calls for the aggregation of exploration assets in cislunar space prior to departure for Mars and utilizes high energy lunar-distant high Earth orbits for the final staging prior to departure. This paper presents the detailed analysis of various cislunar operations for the EMC Hybrid architecture as well as the result of the higher fidelity end-to-end trajectory analysis to understand the implications of the design choices on the Mars exploration campaign.

  18. End-to-end performance of cooperative relaying in spectrum-sharing systems with quality of service requirements

    KAUST Repository

    Asghari, Vahid Reza

    2011-07-01

    We propose adopting a cooperative relaying technique in spectrum-sharing cognitive radio (CR) systems to more effectively and efficiently utilize available transmission resources, such as power, rate, and bandwidth, while adhering to the quality of service (QoS) requirements of the licensed (primary) users of the shared spectrum band. In particular, we first consider that the cognitive (secondary) user\\'s communication is assisted by an intermediate relay that implements the decode-and-forward (DF) technique onto the secondary user\\'s relayed signal to help with communication between the corresponding source and the destination nodes. In this context, we obtain first-order statistics pertaining to the first- and second-hop transmission channels, and then, we investigate the end-to-end performance of the proposed spectrum-sharing cooperative relaying system under resource constraints defined to assure that the primary QoS is unaffected. Specifically, we investigate the overall average bit error rate (BER), ergodic capacity, and outage probability of the secondary\\'s communication subject to appropriate constraints on the interference power at the primary receivers. We then consider a general scenario where a cluster of relays is available between the secondary source and destination nodes. In this case, making use of the partial relay selection method, we generalize our results for the single-relay scheme and obtain the end-to-end performance of the cooperative spectrum-sharing system with a cluster of L available relays. Finally, we examine our theoretical results through simulations and comparisons, illustrating the overall performance of the proposed spectrum-sharing cooperative system and quantify its advantages for different operating scenarios and conditions. © 2011 IEEE.

  19. SU-E-T-282: Dose Measurements with An End-To-End Audit Phantom for Stereotactic Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Jones, R; Artschan, R [Calvary Mater Newcastle, Newcastle, NSW (Australia); Thwaites, D [University of Sydney, Sydney, NSW (Australia); Lehmann, J [Calvary Mater Newcastle, Newcastle, NSW (Australia); University of Sydney, Sydney, NSW (Australia)

    2015-06-15

    Purpose: Report on dose measurements as part of an end-to-end test for stereotactic radiotherapy, using a new audit tool, which allows audits to be performed efficiently either by an onsite team or as a postal audit. Methods: Film measurements have been performed with a new Stereotactic Cube Phantom. The phantom has been designed to perform Winston Lutz type position verification measurements and dose measurements in one setup. It comprises a plastic cube with a high density ball in its centre (used for MV imaging with film or EPID) and low density markers in the periphery (used for Cone Beam Computed Tomography, CBCT imaging). It also features strategically placed gold markers near the posterior and right surfaces, which can be used to calculate phantom rotations on MV images. Slit-like openings allow insertion of film or other detectors.The phantom was scanned and small field treatment plans were created. The fields do not traverse any inhomogeneities of the phantom on their paths to the measurement location. The phantom was setup at the delivery system using CBCT imaging. The calculated treatment fields were delivered, each with a piece of radiochromic film (EBT3) placed in the anterior film holder of the phantom. MU had been selected in planning to achieve similar exposures on all films. Calibration films were exposed in solid water for dose levels around the expected doses. Films were scanned and analysed following established procedures. Results: Setup of the cube showed excellent suitability for CBCT 3D alignment. MV imaging with EPID allowed for clear identification of all markers. Film based dose measurements showed good agreement for MLC created fields down to 0.5 mm × 0.5 mm. Conclusion: An end-to-end audit phantom for stereotactic radiotherapy has been developed and tested.

  20. Evaluation of Techniques to Detect Significant Network Performance Problems using End-to-End Active Network Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Cottrell, R.Les; Logg, Connie; Chhaparia, Mahesh; /SLAC; Grigoriev, Maxim; /Fermilab; Haro, Felipe; /Chile U., Catolica; Nazir, Fawad; /NUST, Rawalpindi; Sandford, Mark

    2006-01-25

    End-to-End fault and performance problems detection in wide area production networks is becoming increasingly hard as the complexity of the paths, the diversity of the performance, and dependency on the network increase. Several monitoring infrastructures are built to monitor different network metrics and collect monitoring information from thousands of hosts around the globe. Typically there are hundreds to thousands of time-series plots of network metrics which need to be looked at to identify network performance problems or anomalous variations in the traffic. Furthermore, most commercial products rely on a comparison with user configured static thresholds and often require access to SNMP-MIB information, to which a typical end-user does not usually have access. In our paper we propose new techniques to detect network performance problems proactively in close to realtime and we do not rely on static thresholds and SNMP-MIB information. We describe and compare the use of several different algorithms that we have implemented to detect persistent network problems using anomalous variations analysis in real end-to-end Internet performance measurements. We also provide methods and/or guidance for how to set the user settable parameters. The measurements are based on active probes running on 40 production network paths with bottlenecks varying from 0.5Mbits/s to 1000Mbit/s. For well behaved data (no missed measurements and no very large outliers) with small seasonal changes most algorithms identify similar events. We compare the algorithms' robustness with respect to false positives and missed events especially when there are large seasonal effects in the data. Our proposed techniques cover a wide variety of network paths and traffic patterns. We also discuss the applicability of the algorithms in terms of their intuitiveness, their speed of execution as implemented, and areas of applicability. Our encouraging results compare and evaluate the accuracy of our

  1. End-to-end models for marine ecosystems: Are we on the precipice of a significant advance or just putting lipstick on a pig?

    Directory of Open Access Journals (Sweden)

    Kenneth A. Rose

    2012-02-01

    Full Text Available There has been a rapid rise in the development of end-to-end models for marine ecosystems over the past decade. Some reasons for this rise include need for predicting effects of climate change on biota and dissatisfaction with existing models. While the benefits of a well-implemented end-to-end model are straightforward, there are many challenges. In the short term, my view is that the major role of end-to-end models is to push the modelling community forward, and to identify critical data so that these data can be collected now and thus be available for the next generation of end-to-end models. I think we should emulate physicists and build theoretically-oriented models first, and then collect the data. In the long-term, end-to-end models will increase their skill, data collection will catch up, and end-to-end models will move towards site-specific applications with forecasting and management capabilities. One pathway into the future is individual efforts, over-promise, and repackaging of poorly performing component submodels (“lipstick on a pig”. The other pathway is a community-based collaborative effort, with appropriate caution and thoughtfulness, so that the needed improvements are achieved (“significant advance”. The promise of end-to-end modelling is great. We should act now to avoid missing a great opportunity.

  2. Unmanned Aircraft Systems Minimum Operations Performance Standards End-to-End Verification and Validation (E2-V2) Simulation

    Science.gov (United States)

    Ghatas, Rania W.; Jack, Devin P.; Tsakpinis, Dimitrios; Vincent, Michael J.; Sturdy, James L.; Munoz, Cesar A.; Hoffler, Keith D.; Dutle, Aaron M.; Myer, Robert R.; Dehaven, Anna M.; hide

    2017-01-01

    As Unmanned Aircraft Systems (UAS) make their way to mainstream aviation operations within the National Airspace System (NAS), research efforts are underway to develop a safe and effective environment for their integration into the NAS. Detect and Avoid (DAA) systems are required to account for the lack of "eyes in the sky" due to having no human on-board the aircraft. The current NAS relies on pilot's vigilance and judgement to remain Well Clear (CFR 14 91.113) of other aircraft. RTCA SC-228 has defined DAA Well Clear (DAAWC) to provide a quantified Well Clear volume to allow systems to be designed and measured against. Extended research efforts have been conducted to understand and quantify system requirements needed to support a UAS pilot's ability to remain well clear of other aircraft. The efforts have included developing and testing sensor, algorithm, alerting, and display requirements. More recently, sensor uncertainty and uncertainty mitigation strategies have been evaluated. This paper discusses results and lessons learned from an End-to-End Verification and Validation (E2-V2) simulation study of a DAA system representative of RTCA SC-228's proposed Phase I DAA Minimum Operational Performance Standards (MOPS). NASA Langley Research Center (LaRC) was called upon to develop a system that evaluates a specific set of encounters, in a variety of geometries, with end-to-end DAA functionality including the use of sensor and tracker models, a sensor uncertainty mitigation model, DAA algorithmic guidance in both vertical and horizontal maneuvering, and a pilot model which maneuvers the ownship aircraft to remain well clear from intruder aircraft, having received collective input from the previous modules of the system. LaRC developed a functioning batch simulation and added a sensor/tracker model from the Federal Aviation Administration (FAA) William J. Hughes Technical Center, an in-house developed sensor uncertainty mitigation strategy, and implemented a pilot

  3. Double 90 Degrees Counterrotated End-to-End-Anastomosis: An Experimental Study of an Intestinal Anastomosis Technique.

    Science.gov (United States)

    Holzner, Philipp; Kulemann, Birte; Seifert, Gabriel; Glatz, Torben; Chikhladze, Sophia; Höppner, Jens; Hopt, Ulrich; Timme, Sylvia; Bronsert, Peter; Sick, Olivia; Zhou, Cheng; Marjanovic, Goran

    2015-06-01

    The aim of the article is to investigate a new anastomotic technique compared with standardized intestinal anastomotic procedures. A total of 32 male Wistar rats were randomized to three groups. In the Experimental Group (n = 10), the new double 90 degrees inversely rotated anastomosis was used, in the End Group (n = 10) a single-layer end-to-end anastomosis, and in the Side Group (n = 12) a single-layer side-to-side anastomosis. All anastomoses were done using interrupted sutures. On postoperative day 4, rats were relaparotomized. Bursting pressure, hydroxyproline concentration, a semiquantitative adhesion score and two histological anastomotic healing scores (mucosal healing according to Chiu and overall anastomotic healing according to Verhofstad) were collected. Most data are presented as median (range). p < 0.05 was considered significant. Anastomotic insufficiency occurred only in one rat of the Side Group. Median bursting pressure in the Experimental Group was 105 mm Hg (range = 72-161 mm Hg), significantly higher in the End Group (164 mm Hg; range = 99-210 mm Hg; p = 0.021) and lower in the Side Group by trend (81 mm Hg; range = 59-122 mm Hg; p = 0.093). Hydroxyproline concentration did not differ significantly in between the groups. The adhesion score was 2.5 (range = 1-3) in the Experimental Group, 2 (range = 1-2) in the End Group, but there were significantly more adhesions in the Side Group (range = 3-4); p = 0.020 versus Experimental Group, p < 0.001 versus End Group. The Chiu Score showed the worst mucosal healing in the Experimental Group. The overall Verhofstad Score was significantly worse (mean = 2.032; standard deviation [SD] = 0.842) p = 0.031 and p = 0.002 in the Experimental Group, compared with the Side Group (mean = 1.729; SD = 0.682) and the End Group (mean = 1.571; SD = 0.612). The new anastomotic technique is feasible and did not show any relevant complication. Even though it was superior to the side-to-side anastomosis by trend with

  4. A novel end-to-end classifier using domain transferred deep convolutional neural networks for biomedical images.

    Science.gov (United States)

    Pang, Shuchao; Yu, Zhezhou; Orgun, Mehmet A

    2017-03-01

    Highly accurate classification of biomedical images is an essential task in the clinical diagnosis of numerous medical diseases identified from those images. Traditional image classification methods combined with hand-crafted image feature descriptors and various classifiers are not able to effectively improve the accuracy rate and meet the high requirements of classification of biomedical images. The same also holds true for artificial neural network models directly trained with limited biomedical images used as training data or directly used as a black box to extract the deep features based on another distant dataset. In this study, we propose a highly reliable and accurate end-to-end classifier for all kinds of biomedical images via deep learning and transfer learning. We first apply domain transferred deep convolutional neural network for building a deep model; and then develop an overall deep learning architecture based on the raw pixels of original biomedical images using supervised training. In our model, we do not need the manual design of the feature space, seek an effective feature vector classifier or segment specific detection object and image patches, which are the main technological difficulties in the adoption of traditional image classification methods. Moreover, we do not need to be concerned with whether there are large training sets of annotated biomedical images, affordable parallel computing resources featuring GPUs or long times to wait for training a perfect deep model, which are the main problems to train deep neural networks for biomedical image classification as observed in recent works. With the utilization of a simple data augmentation method and fast convergence speed, our algorithm can achieve the best accuracy rate and outstanding classification ability for biomedical images. We have evaluated our classifier on several well-known public biomedical datasets and compared it with several state-of-the-art approaches. We propose a robust

  5. End-to-end Cyberinfrastructure and Data Services for Earth System Science Education and Research: A vision for the future

    Science.gov (United States)

    Ramamurthy, M. K.

    2006-05-01

    yet revolutionary way of building applications and methods to connect and exchange information over the Web. This new approach, based on XML - a widely accepted format for exchanging data and corresponding semantics over the Internet - enables applications, computer systems, and information processes to work together in fundamentally different ways. Likewise, the advent of digital libraries, grid computing platforms, interoperable frameworks, standards and protocols, open-source software, and community atmospheric models have been important drivers in shaping the use of a new generation of end-to-end cyberinfrastructure for solving some of the most challenging scientific and educational problems. In this talk, I will present an overview of the scientific, technological, and educational landscape, discuss recent developments in cyberinfrastructure, and Unidata's role in and vision for providing easy-to use, robust, end-to-end data services for solving geoscientific problems and advancing student learning.

  6. End-to-end Cyberinfrastructure and Data Services for Earth System Science Education and Research: Unidata's Plans and Directions

    Science.gov (United States)

    Ramamurthy, M.

    2005-12-01

    work together in a fundamentally different way. Likewise, the advent of digital libraries, grid computing platforms, interoperable frameworks, standards and protocols, open-source software, and community atmospheric models have been important drivers in shaping the use of a new generation of end-to-end cyberinfrastructure for solving some of the most challenging scientific and educational problems. In this talk, I will present an overview of the scientific, technological, and educational drivers and discuss recent developments in cyberinfrastructure and Unidata's role and directions in providing robust, end-to-end data services for solving geoscientific problems and advancing student learning.

  7. SU-F-J-177: A Novel Image Analysis Technique (center Pixel Method) to Quantify End-To-End Tests

    Energy Technology Data Exchange (ETDEWEB)

    Wen, N; Chetty, I [Henry Ford Health System, Detroit, MI (United States); Snyder, K [Henry Ford Hospital System, Detroit, MI (United States); Scheib, S [Varian Medical System, Barton (Switzerland); Qin, Y; Li, H [Henry Ford Health System, Detroit, Michigan (United States)

    2016-06-15

    Purpose: To implement a novel image analysis technique, “center pixel method”, to quantify end-to-end tests accuracy of a frameless, image guided stereotactic radiosurgery system. Methods: The localization accuracy was determined by delivering radiation to an end-to-end prototype phantom. The phantom was scanned with 0.8 mm slice thickness. The treatment isocenter was placed at the center of the phantom. In the treatment room, CBCT images of the phantom (kVp=77, mAs=1022, slice thickness 1 mm) were acquired to register to the reference CT images. 6D couch correction were applied based on the registration results. Electronic Portal Imaging Device (EPID)-based Winston Lutz (WL) tests were performed to quantify the errors of the targeting accuracy of the system at 15 combinations of gantry, collimator and couch positions. The images were analyzed using two different methods. a) The classic method. The deviation was calculated by measuring the radial distance between the center of the central BB and the full width at half maximum of the radiation field. b) The center pixel method. Since the imager projection offset from the treatment isocenter was known from the IsoCal calibration, the deviation was determined between the center of the BB and the central pixel of the imager panel. Results: Using the automatic registration method to localize the phantom and the classic method of measuring the deviation of the BB center, the mean and standard deviation of the radial distance was 0.44 ± 0.25, 0.47 ± 0.26, and 0.43 ± 0.13 mm for the jaw, MLC and cone defined field sizes respectively. When the center pixel method was used, the mean and standard deviation was 0.32 ± 0.18, 0.32 ± 0.17, and 0.32 ± 0.19 mm respectively. Conclusion: Our results demonstrated that the center pixel method accurately analyzes the WL images to evaluate the targeting accuracy of the radiosurgery system. The work was supported by a Research Scholar Grant, RSG-15-137-01-CCE from the American

  8. A new standard method for the surveying and alignment of beamline facilities at GSI

    Energy Technology Data Exchange (ETDEWEB)

    Wirth, H. [Metronom, Gesellschaft fuer Industrievermessung mbH, Mainz (Germany); Moritz, G.

    1996-01-01

    The GSI institute of heavy ion research is financed by the country of Germany. Founded in 1969, the main emphasis of the institute`s work is the research of the characteristics of atomic nuclei. The Universal Linear Accelerator UNILAC was built first and in 1987 new facilities were added to the setup. The GSI accelarators allow acceleration of all atomic nuclei up to Uranium to an energy of 20 MeV/u. In 1993 Metronome started working on a new alignment concept for the GSI`s accelerators. Metronome has developed the TASA concept. TSAS stands for Techeometric Accelerator Surveying and Alignment and is based on the new generation of high-precision total stations. One feature included in the TASA Concept, has been the replacement of all mobile plates by fixed consoles. An immense advantage of new fixed consoles, welded onto every component, is that they can be positioned to locations where they can be easily measured, simply by taking measuring conditions (lines of sight, heights of stands, error-figures, configuration, etc.) into consideration. The TASA Concept can be used for all alignments of the different GSI accelerators. For all accelerators a special investigation was carried out to check if it is possible to position a new pillar system and to install new consoles on the components. The free positioning of fiducial points makes it possible to use polar measurements for all components. This is an enormous advantage and a step forward for alignment procedures at GSI. Furthermore, use of a total station as opposed to the ECDS System means that one operator less is needed. (S.Y.)

  9. APS beamline standard components handbook

    International Nuclear Information System (INIS)

    Kuzay, T.M.

    1992-01-01

    It is clear that most Advanced Photon Source (APS) Collaborative Access Team (CAT) members would like to concentrate on designing specialized equipment related to their scientific programs rather than on routine or standard beamline components. Thus, an effort is in progress at the APS to identify standard and modular components of APS beamlines. Identifying standard components is a nontrivial task because these components should support diverse beamline objectives. To assist with this effort, the APS has obtained advice and help from a Beamline Standardization and Modularization Committee consisting of experts in beamline design, construction, and operation. The staff of the Experimental Facilities Division identified various components thought to be standard items for beamlines, regardless of the specific scientific objective of a particular beamline. A generic beamline layout formed the basis for this identification. This layout is based on a double-crystal monochromator as the first optical element, with the possibility of other elements to follow. Pre-engineering designs were then made of the identified standard components. The Beamline Standardization and Modularization Committee has reviewed these designs and provided very useful input regarding the specifications of these components. We realize that there will be other configurations that may require special or modified components. This Handbook in its current version (1.1) contains descriptions, specifications, and pre-engineering design drawings of these standard components. In the future, the APS plans to add engineering drawings of identified standard beamline components. Use of standard components should result in major cost reductions for CATs in the areas of beamline design and construction

  10. End-to-end probability for an interacting center vortex world line in Yang-Mills theory

    International Nuclear Information System (INIS)

    Teixeira, Bruno F.I.; Lemos, Andre L.L. de; Oxman, Luis E.

    2011-01-01

    Full text: The understanding of quark confinement is a very important open problem in Yang-Mills theory. In this regard, nontrivial topological defects are expected to play a relevant role to achieve a solution. Here we are interested in how to deal with these structures, relying on the Cho-Faddeev-Niemi decomposition and the possibility it offers to describe defects in terms of a local color frame. In particular, the path integral for a single center vortex is a fundamental object to handle the ensemble integration. As is well-known, in three dimensions center vortices are string-like and the associated physics is closely related with that of polymers. Using recent techniques developed in the latter context, we present in this work a detailed derivation of the equation for the end-to-end probability for a center vortex world line, including the effects of interactions. Its solution can be associated with a Green function that depends on the position and orientation at the boundaries, where monopole-like instantons are placed. In the limit of semi flexible polymers, an expansion only keeping the lower angular momenta for the final orientation leads to a reduced Green function for a complex vortex field minimally coupled to the dual Yang-Mills fields. This constitutes a key ingredient to propose an effective model for correlated monopoles, center vortices and the dual fields. (author)

  11. Minimizing Barriers in Learning for On-Call Radiology Residents-End-to-End Web-Based Resident Feedback System.

    Science.gov (United States)

    Choi, Hailey H; Clark, Jennifer; Jay, Ann K; Filice, Ross W

    2018-02-01

    Feedback is an essential part of medical training, where trainees are provided with information regarding their performance and further directions for improvement. In diagnostic radiology, feedback entails a detailed review of the differences between the residents' preliminary interpretation and the attendings' final interpretation of imaging studies. While the on-call experience of independently interpreting complex cases is important to resident education, the more traditional synchronous "read-out" or joint review is impossible due to multiple constraints. Without an efficient method to compare reports, grade discrepancies, convey salient teaching points, and view images, valuable lessons in image interpretation and report construction are lost. We developed a streamlined web-based system, including report comparison and image viewing, to minimize barriers in asynchronous communication between attending radiologists and on-call residents. Our system provides real-time, end-to-end delivery of case-specific and user-specific feedback in a streamlined, easy-to-view format. We assessed quality improvement subjectively through surveys and objectively through participation metrics. Our web-based feedback system improved user satisfaction for both attending and resident radiologists, and increased attending participation, particularly with regards to cases where substantive discrepancies were identified.

  12. An anthropomorphic multimodality (CT/MRI) head phantom prototype for end-to-end tests in ion radiotherapy

    International Nuclear Information System (INIS)

    Gallas, Raya R.; Huenemohr, Nora; Runz, Armin; Niebuhr, Nina I.; Greilich, Steffen; Jaekel, Oliver

    2015-01-01

    With the increasing complexity of external beam therapy ''end-to-end'' tests are intended to cover every step from therapy planning through to follow-up in order to fulfill the higher demands on quality assurance. As magnetic resonance imaging (MRI) has become an important part of the treatment process, established phantoms such as the Alderson head cannot fully be used for those tests and novel phantoms have to be developed. Here, we present a feasibility study of a customizable multimodality head phantom. It is initially intended for ion radiotherapy but may also be used in photon therapy. As basis for the anthropomorphic head shape we have used a set of patient computed tomography (CT) images. The phantom recipient consisting of epoxy resin was produced by using a 3D printer. It includes a nasal air cavity, a cranial bone surrogate (based on dipotassium phosphate), a brain surrogate (based on agarose gel), and a surrogate for cerebrospinal fluid (based on distilled water). Furthermore, a volume filled with normoxic dosimetric gel mimicked a tumor. The entire workflow of a proton therapy could be successfully applied to the phantom. CT measurements revealed CT numbers agreeing with reference values for all surrogates in the range from 2 HU to 978 HU (120 kV). MRI showed the desired contrasts between the different phantom materials especially in T2-weighted images (except for the bone surrogate). T2-weighted readout of the polymerization gel dosimeter allowed approximate range verification.

  13. Vision-based mobile robot navigation through deep convolutional neural networks and end-to-end learning

    Science.gov (United States)

    Zhang, Yachu; Zhao, Yuejin; Liu, Ming; Dong, Liquan; Kong, Lingqin; Liu, Lingling

    2017-09-01

    In contrast to humans, who use only visual information for navigation, many mobile robots use laser scanners and ultrasonic sensors along with vision cameras to navigate. This work proposes a vision-based robot control algorithm based on deep convolutional neural networks. We create a large 15-layer convolutional neural network learning system and achieve the advanced recognition performance. Our system is trained from end to end to map raw input images to direction in supervised mode. The images of data sets are collected in a wide variety of weather conditions and lighting conditions. Besides, the data sets are augmented by adding Gaussian noise and Salt-and-pepper noise to avoid overfitting. The algorithm is verified by two experiments, which are line tracking and obstacle avoidance. The line tracking experiment is proceeded in order to track the desired path which is composed of straight and curved lines. The goal of obstacle avoidance experiment is to avoid the obstacles indoor. Finally, we get 3.29% error rate on the training set and 5.1% error rate on the test set in the line tracking experiment, 1.8% error rate on the training set and less than 5% error rate on the test set in the obstacle avoidance experiment. During the actual test, the robot can follow the runway centerline outdoor and avoid the obstacle in the room accurately. The result confirms the effectiveness of the algorithm and our improvement in the network structure and train parameters

  14. SampleCNN: End-to-End Deep Convolutional Neural Networks Using Very Small Filters for Music Classification

    Directory of Open Access Journals (Sweden)

    Jongpil Lee

    2018-01-01

    Full Text Available Convolutional Neural Networks (CNN have been applied to diverse machine learning tasks for different modalities of raw data in an end-to-end fashion. In the audio domain, a raw waveform-based approach has been explored to directly learn hierarchical characteristics of audio. However, the majority of previous studies have limited their model capacity by taking a frame-level structure similar to short-time Fourier transforms. We previously proposed a CNN architecture which learns representations using sample-level filters beyond typical frame-level input representations. The architecture showed comparable performance to the spectrogram-based CNN model in music auto-tagging. In this paper, we extend the previous work in three ways. First, considering the sample-level model requires much longer training time, we progressively downsample the input signals and examine how it affects the performance. Second, we extend the model using multi-level and multi-scale feature aggregation technique and subsequently conduct transfer learning for several music classification tasks. Finally, we visualize filters learned by the sample-level CNN in each layer to identify hierarchically learned features and show that they are sensitive to log-scaled frequency.

  15. An anthropomorphic multimodality (CT/MRI) head phantom prototype for end-to-end tests in ion radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Gallas, Raya R.; Huenemohr, Nora; Runz, Armin; Niebuhr, Nina I.; Greilich, Steffen [German Cancer Research Center (DKFZ), Heidelberg (Germany). Div. of Medical Physics in Radiation Oncology; National Center for Radiation Research in Oncology, Heidelberg (Germany). Heidelberg Institute of Radiation Oncology (HIRO); Jaekel, Oliver [German Cancer Research Center (DKFZ), Heidelberg (Germany). Div. of Medical Physics in Radiation Oncology; National Center for Radiation Research in Oncology, Heidelberg (Germany). Heidelberg Institute of Radiation Oncology (HIRO); Heidelberg University Hospital (Germany). Dept. of Radiation Oncology; Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg (Germany)

    2015-07-01

    With the increasing complexity of external beam therapy ''end-to-end'' tests are intended to cover every step from therapy planning through to follow-up in order to fulfill the higher demands on quality assurance. As magnetic resonance imaging (MRI) has become an important part of the treatment process, established phantoms such as the Alderson head cannot fully be used for those tests and novel phantoms have to be developed. Here, we present a feasibility study of a customizable multimodality head phantom. It is initially intended for ion radiotherapy but may also be used in photon therapy. As basis for the anthropomorphic head shape we have used a set of patient computed tomography (CT) images. The phantom recipient consisting of epoxy resin was produced by using a 3D printer. It includes a nasal air cavity, a cranial bone surrogate (based on dipotassium phosphate), a brain surrogate (based on agarose gel), and a surrogate for cerebrospinal fluid (based on distilled water). Furthermore, a volume filled with normoxic dosimetric gel mimicked a tumor. The entire workflow of a proton therapy could be successfully applied to the phantom. CT measurements revealed CT numbers agreeing with reference values for all surrogates in the range from 2 HU to 978 HU (120 kV). MRI showed the desired contrasts between the different phantom materials especially in T2-weighted images (except for the bone surrogate). T2-weighted readout of the polymerization gel dosimeter allowed approximate range verification.

  16. Innovative strategy for effective critical laboratory result management: end-to-end process using automation and manual call centre.

    Science.gov (United States)

    Ti, Lian Kah; Ang, Sophia Bee Leng; Saw, Sharon; Sethi, Sunil Kumar; Yip, James W L

    2012-08-01

    Timely reporting and acknowledgement are crucial steps in critical laboratory results (CLR) management. The authors previously showed that an automated pathway incorporating short messaging system (SMS) texts, auto-escalation, and manual telephone back-up improved the rate and speed of physician acknowledgement compared with manual telephone calling alone. This study investigated if it also improved the rate and speed of physician intervention to CLR and whether utilising the manual back-up affected intervention rates. Data from seven audits between November 2007 and January 2011 were analysed. These audits were carried out to assess the robustness of CLR reporting process in the authors' institution. Comparisons were made in the rate and speed of acknowledgement and intervention between the audits performed before and after automation. Using the automation audits, the authors compared intervention data between communication with SMS only and when manual intervention was required. 1680 CLR were reported during the audit periods. Automation improved the rate (100% vs 84.2%; pautomation audits, the use of SMS only did not improve physician intervention rates. The automated communication pathway improved physician intervention rate and time in tandem with improved acknowledgement rate and time when compared with manual telephone calling. The use of manual intervention to augment automation did not adversely affect physician intervention rate, implying that an end-to-end pathway was more important than automation alone.

  17. Delayed primary end-to-end anastomosis for traumatic long segment urethral stricture and its short-term outcomes

    Directory of Open Access Journals (Sweden)

    Rajarshi Kumar

    2017-01-01

    Full Text Available Background: The purpose of this study is to evaluate the aetiology of posterior urethral stricture in children and analysis of results after delayed primary repair with extensive distal urethral mobilisation. Materials and Methods: This was a retrospective study carried out in a tertiary care centre from January 2009 to December 2013. Results: Eight children with median age 7.5 years (range 4–11 years, underwent delayed anastomotic urethroplasty: Six through perineal and two through combined perineal and transpubic approach. All the eight children had long-segment >2 cm stricture: Three posterior and five anterior urethral stricture. On a mean follow-up period of 33 months (range 24–48 m, all were passing urine with good flow and stream. Conclusion: End-to-end anastomosis in post-traumatic long segment posterior urethral stricture between prostatic and penile urethra in children is possible by perineal or combined perineal and transpubic approach with good results without any urethral replacement.

  18. A real-time 3D end-to-end augmented reality system (and its representation transformations)

    Science.gov (United States)

    Tytgat, Donny; Aerts, Maarten; De Busser, Jeroen; Lievens, Sammy; Rondao Alface, Patrice; Macq, Jean-Francois

    2016-09-01

    The new generation of HMDs coming to the market is expected to enable many new applications that allow free viewpoint experiences with captured video objects. Current applications usually rely on 3D content that is manually created or captured in an offline manner. In contrast, this paper focuses on augmented reality applications that use live captured 3D objects while maintaining free viewpoint interaction. We present a system that allows live dynamic 3D objects (e.g. a person who is talking) to be captured in real-time. Real-time performance is achieved by traversing a number of representation formats and exploiting their specific benefits. For instance, depth images are maintained for fast neighborhood retrieval and occlusion determination, while implicit surfaces are used to facilitate multi-source aggregation for both geometry and texture. The result is a 3D reconstruction system that outputs multi-textured triangle meshes at real-time rates. An end-to-end system is presented that captures and reconstructs live 3D data and allows for this data to be used on a networked (AR) device. For allocating the different functional blocks onto the available physical devices, a number of alternatives are proposed considering the available computational power and bandwidth for each of the components. As we will show, the representation format can play an important role in this functional allocation and allows for a flexible system that can support a highly heterogeneous infrastructure.

  19. Increasing gas producer profitability with virtual well visibility via an end-to-end, wireless Internet gas monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, M.; Coleman, K.; Beck, R.; Lyon, R.; Potts, R. [Northrock Resources Ltd., Calgary, AB (Canada); Benterud, K. [Zed.i solutions, Calgary, AB (Canada)

    2003-07-01

    Most gas producing companies still use 100-year old technology to measure gas volumes because of the prohibitive costs of implementing corporate wide electronic information systems to replace circular mechanical chart technology. This paper describes how Northrock Resources Ltd. increased profitability using Smart-Alek{sup TM} while avoiding high implementation costs. Smart-Alek is a new type of fully integrated end-to-end electronic gas flow measurement (GFM) system based on Field Intelligence Network and End User Interference (FINE). Smart-Alek can analyze gas production through public wireless communications and a web-browser delivery system. The system has enabled Northrock to increase gas volumes with more accurate measurement and reduced downtime. In addition, operating costs were also decreased because the frequency of well visits was reduced and the administrative procedures of data collection was more efficient. The real-time well visibility of the tool has proven to be very effective in optimizing business profitability. 9 refs., 1 tab., 9 figs.

  20. End-to-end gene fusions and their impact on the production of multifunctional biomass degrading enzymes

    International Nuclear Information System (INIS)

    Rizk, Mazen; Antranikian, Garabed; Elleuche, Skander

    2012-01-01

    Highlights: ► Multifunctional enzymes offer an interesting approach for biomass degradation. ► Size and conformation of separate constructs play a role in the effectiveness of chimeras. ► A connecting linker allows for maximal flexibility and increased thermostability. ► Genes with functional similarities are the best choice for fusion candidates. -- Abstract: The reduction of fossil fuels, coupled with its increase in price, has made the search for alternative energy resources more plausible. One of the topics gaining fast interest is the utilization of lignocellulose, the main component of plants. Its primary constituents, cellulose and hemicellulose, can be degraded by a series of enzymes present in microorganisms, into simple sugars, later used for bioethanol production. Thermophilic bacteria have proven to be an interesting source of enzymes required for hydrolysis since they can withstand high and denaturing temperatures, which are usually required for processes involving biomass degradation. However, the cost associated with the whole enzymatic process is staggering. A solution for cost effective and highly active production is through the construction of multifunctional enzyme complexes harboring the function of more than one enzyme needed for the hydrolysis process. There are various strategies for the degradation of complex biomass ranging from the regulation of the enzymes involved, to cellulosomes, and proteins harboring more than one enzymatic activity. In this review, the construction of multifunctional biomass degrading enzymes through end-to-end gene fusions, and its impact on production and activity by choosing the enzymes and linkers is assessed.

  1. An anthropomorphic multimodality (CT/MRI) head phantom prototype for end-to-end tests in ion radiotherapy.

    Science.gov (United States)

    Gallas, Raya R; Hünemohr, Nora; Runz, Armin; Niebuhr, Nina I; Jäkel, Oliver; Greilich, Steffen

    2015-12-01

    With the increasing complexity of external beam therapy "end-to-end" tests are intended to cover every step from therapy planning through to follow-up in order to fulfill the higher demands on quality assurance. As magnetic resonance imaging (MRI) has become an important part of the treatment process, established phantoms such as the Alderson head cannot fully be used for those tests and novel phantoms have to be developed. Here, we present a feasibility study of a customizable multimodality head phantom. It is initially intended for ion radiotherapy but may also be used in photon therapy. As basis for the anthropomorphic head shape we have used a set of patient computed tomography (CT) images. The phantom recipient consisting of epoxy resin was produced by using a 3D printer. It includes a nasal air cavity, a cranial bone surrogate (based on dipotassium phosphate), a brain surrogate (based on agarose gel), and a surrogate for cerebrospinal fluid (based on distilled water). Furthermore, a volume filled with normoxic dosimetric gel mimicked a tumor. The entire workflow of a proton therapy could be successfully applied to the phantom. CT measurements revealed CT numbers agreeing with reference values for all surrogates in the range from 2 HU to 978 HU (120 kV). MRI showed the desired contrasts between the different phantom materials especially in T2-weighted images (except for the bone surrogate). T2-weighted readout of the polymerization gel dosimeter allowed approximate range verification. Copyright © 2015. Published by Elsevier GmbH.

  2. On cryptographic security of end-to-end encrypted connections in WhatsApp and Telegram messengers

    Directory of Open Access Journals (Sweden)

    Sergey V. Zapechnikov

    2017-11-01

    Full Text Available The aim of this work is to analyze the available possibilities for improving secure messaging with end-to-end connections under conditions of external violator actions and distrusted service provider. We made a comparative analysis of cryptographic security mechanisms for two widely used messengers: Telegram and WhatsApp. It was found that Telegram is based on MTProto protocol, while WhatsApp is based on the alternative Signal protocol. We examine the specific features of messengers implementation associated with random number generation on the most popular Android mobile platform. It was shown that Signal has better security properties. It is used in several other popular messengers such as TextSecure, RedPhone, GoogleAllo, FacebookMessenger, Signal along with WhatsApp. A number of possible attacks on both messengers were analyzed in details. In particular, we demonstrate that the metadata are poorly protected in both messengers. Metadata security may be one of the goals for further studies.

  3. Secondary link adaptation in cognitive radio networks: End-to-end performance with cross-layer design

    KAUST Repository

    Ma, Hao

    2012-04-01

    Under spectrum-sharing constraints, we consider the secondary link exploiting cross-layer combining of adaptive modulation and coding (AMC) at the physical layer with truncated automatic repeat request (T-ARQ) at the data link layer in cognitive radio networks. Both, basic AMC and aggressive AMC, are adopted to optimize the overall average spectral efficiency, subject to the interference constraints imposed by the primary user of the shared spectrum band and a target packet loss rate. We achieve the optimal boundary points in closed form to choose the AMC transmission modes by taking into account the channel state information from the secondary transmitter to both the primary receiver and the secondary receiver. Moreover, numerical results substantiate that, without any cost in the transmitter/receiver design nor the end-to-end delay, the scheme with aggressive AMC outperforms that with conventional AMC. The main reason is that, with aggressive AMC, different transmission modes utilized in the initial packet transmission and the following retransmissions match the time-varying channel conditions better than the basic pattern. © 2012 IEEE.

  4. Chinese Medical Question Answer Matching Using End-to-End Character-Level Multi-Scale CNNs

    Directory of Open Access Journals (Sweden)

    Sheng Zhang

    2017-07-01

    Full Text Available This paper focuses mainly on the problem of Chinese medical question answer matching, which is arguably more challenging than open-domain question answer matching in English due to the combination of its domain-restricted nature and the language-specific features of Chinese. We present an end-to-end character-level multi-scale convolutional neural framework in which character embeddings instead of word embeddings are used to avoid Chinese word segmentation in text preprocessing, and multi-scale convolutional neural networks (CNNs are then introduced to extract contextual information from either question or answer sentences over different scales. The proposed framework can be trained with minimal human supervision and does not require any handcrafted features, rule-based patterns, or external resources. To validate our framework, we create a new text corpus, named cMedQA, by harvesting questions and answers from an online Chinese health and wellness community. The experimental results on the cMedQA dataset show that our framework significantly outperforms several strong baselines, and achieves an improvement of top-1 accuracy by up to 19%.

  5. West Coast fish, mammal, and bird species diets - Developing end-to-end models of the California Current Large Marine Ecosystem

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the California Current LME, linking oceanography, biogeochemistry, food web...

  6. Gulf of California species and catch spatial distributions and historical time series - Developing end-to-end models of the Gulf of California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the northern Gulf of California, linking oceanography, biogeochemistry, food web...

  7. West Coast fish, mammal, bird life history and abunance parameters - Developing end-to-end models of the California Current Large Marine Ecosystem

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of this project is to develop spatially discrete end-to-end models of the California Current LME, linking oceanography, biogeochemistry, food web...

  8. Simulation of a high energy neutron irradiation facility at beamline 11 of the China Spallation Neutron Source

    Energy Technology Data Exchange (ETDEWEB)

    Tairan, Liang [School of Physics and Electronic Information Inner Mongolia University for the Nationalities, Tongliao 028043 (China); Zhiduo, Li [Dongguan Branch, Institute of High Energy Physics, CAS, Beijing 100049 (China); Wen, Yin, E-mail: wenyin@aphy.iphy.ac.cn [Dongguan Branch, Institute of High Energy Physics, CAS, Beijing 100049 (China); Institute of Physics, CAS, P.O. Box 603, Beijing 100190 (China); Fei, Shen [Dongguan Branch, Institute of High Energy Physics, CAS, Beijing 100049 (China); Quanzhi, Yu [Dongguan Branch, Institute of High Energy Physics, CAS, Beijing 100049 (China); Institute of Physics, CAS, P.O. Box 603, Beijing 100190 (China); Tianjiao, Liang [Dongguan Branch, Institute of High Energy Physics, CAS, Beijing 100049 (China)

    2017-07-11

    The China Spallation Neutron Source (CSNS) will accommodate 20 neutron beamlines at its first target station. These beamlines serve different purposes, and beamline 11 is designed to analyze the degraded models and damage mechanisms, such as Single Event Effects in electronic components and devices for aerospace electronic systems. This paper gives a preliminary discussion on the scheme of a high energy neutron irradiation experiment at the beamline 11 shutter based on the Monte Carlo simulation method. The neutron source term is generated by calculating the neutrons scattering into beamline 11 with a model that includes the target-moderator-reflector area. Then, the neutron spectrum at the sample position is obtained. The intensity of neutrons with energy of hundreds of MeV is approximately 1E8 neutron/cm{sup 2}/s, which is useful for experiments. The displacement production rate and gas productions are calculated for common materials such as tungsten, tantalum and SS316. The results indicate that the experiment can provide irradiation dose rate ranges from 1E-5 to 1E-4 dpa per operating year. The residual radioactivity is also calculated for regular maintenance work. These results give the basic reference for the experimental design.

  9. Geometrical layout and optics modelling of the surface science beamline station at the SESAME synchrotron radiation facility.

    Science.gov (United States)

    Salah, Wa'el; Sanchez del Rio, Manuel

    2011-05-01

    The layout and the optical performance of the SGM branch of the D09 bending-magnet beamline, under construction at SESAME, are presented. The beamline is based on the Dragon-type design and delivers photons over the spectral range 15-250 eV. One fixed entrance slit and a movable exit slit are used. The performance of the beamline has been characterized by calculating the mirror reflectivities and the grating efficiencies. The flux and resolution were calculated by ray-tracing using SHADOW. The grating diffraction efficiencies were calculated using the GRADIF code. The results and the overall shapes of the predicted curves are in reasonable agreement with those obtained using an analytical formula.

  10. Adaptation and validation of a commercial head phantom for cranial radiosurgery dosimetry end-to-end audit.

    Science.gov (United States)

    Dimitriadis, Alexis; Palmer, Antony L; Thomas, Russell A S; Nisbet, Andrew; Clark, Catharine H

    2017-06-01

    To adapt and validate an anthropomorphic head phantom for use in a cranial radiosurgery audit. Two bespoke inserts were produced for the phantom: one for providing the target and organ at risk for delineation and the other for performing dose measurements. The inserts were tested to assess their positional accuracy. A basic treatment plan dose verification with an ionization chamber was performed to establish a baseline accuracy for the phantom and beam model. The phantom and inserts were then used to perform dose verification measurements of a radiosurgery plan. The dose was measured with alanine pellets, EBT extended dose film and a plastic scintillation detector (PSD). Both inserts showed reproducible positioning (±0.5 mm) and good positional agreement between them (±0.6 mm). The basic treatment plan measurements showed agreement to the treatment planning system (TPS) within 0.5%. Repeated film measurements showed consistent gamma passing rates with good agreement to the TPS. For 2%-2 mm global gamma, the mean passing rate was 96.7% and the variation in passing rates did not exceed 2.1%. The alanine pellets and PSD showed good agreement with the TPS (-0.1% and 0.3% dose difference in the target) and good agreement with each other (within 1%). The adaptations to the phantom showed acceptable accuracies. The presence of alanine and PSD do not affect film measurements significantly, enabling simultaneous measurements by all three detectors. Advances in knowledge: A novel method for thorough end-to-end test of radiosurgery, with capability to incorporate all steps of the clinical pathway in a time-efficient and reproducible manner, suitable for a national audit.

  11. End-to-end simulations and planning of a small space telescopes: Galaxy Evolution Spectroscopic Explorer: a case study

    Science.gov (United States)

    Heap, Sara; Folta, David; Gong, Qian; Howard, Joseph; Hull, Tony; Purves, Lloyd

    2016-08-01

    Large astronomical missions are usually general-purpose telescopes with a suite of instruments optimized for different wavelength regions, spectral resolutions, etc. Their end-to-end (E2E) simulations are typically photons-in to flux-out calculations made to verify that each instrument meets its performance specifications. In contrast, smaller space missions are usually single-purpose telescopes, and their E2E simulations start with the scientific question to be answered and end with an assessment of the effectiveness of the mission in answering the scientific question. Thus, E2E simulations for small missions consist a longer string of calculations than for large missions, as they include not only the telescope and instrumentation, but also the spacecraft, orbit, and external factors such as coordination with other telescopes. Here, we illustrate the strategy and organization of small-mission E2E simulations using the Galaxy Evolution Spectroscopic Explorer (GESE) as a case study. GESE is an Explorer/Probe-class space mission concept with the primary aim of understanding galaxy evolution. Operation of a small survey telescope in space like GESE is usually simpler than operations of large telescopes driven by the varied scientific programs of the observers or by transient events. Nevertheless, both types of telescopes share two common challenges: maximizing the integration time on target, while minimizing operation costs including communication costs and staffing on the ground. We show in the case of GESE how these challenges can be met through a custom orbit and a system design emphasizing simplification and leveraging information from ground-based telescopes.

  12. Beamlines on the SPring-8 project

    Energy Technology Data Exchange (ETDEWEB)

    Ohno, Hideo [Japan Atomic Energy Research Inst., Kamigori, Hyogo (Japan). Kansai Research Establishment

    1997-03-01

    SPring-8 project is going to construct a ultrahigh-brilliance X-ray synchrotron radiation facility and commissioning of the storage ring is expected in Spring 1977. The facility will be available to scientists and engineers of universities, national laboratories and industries not only from Japan but also from abroad. 20 proposals for public beamlines are submitted to the Beamline Committee and the ten public beamlines are scheduled for completion by the end of 1997. (author)

  13. First Demonstration of Real-Time End-to-End 40 Gb/s PAM-4 System using 10-G Transmitter for Next Generation Access Applications

    DEFF Research Database (Denmark)

    Wei, Jinlong; Eiselt, Nicklas; Griesser, Helmut

    We demonstrate the first known experiment of a real-time end-to-end 40-Gb/s PAM-4 system for next generation access applications using 10G class transmitters only. Up to 25-dB upstream link budget for 20 km SMF is achieved.......We demonstrate the first known experiment of a real-time end-to-end 40-Gb/s PAM-4 system for next generation access applications using 10G class transmitters only. Up to 25-dB upstream link budget for 20 km SMF is achieved....

  14. CAT-ACT—A new highly versatile x-ray spectroscopy beamline for catalysis and radionuclide science at the KIT synchrotron light facility ANKA

    Science.gov (United States)

    Zimina, A.; Dardenne, K.; Denecke, M. A.; Doronkin, D. E.; Huttel, E.; Lichtenberg, H.; Mangold, S.; Pruessmann, T.; Rothe, J.; Spangenberg, Th.; Steininger, R.; Vitova, T.; Geckeis, H.; Grunwaldt, J.-D.

    2017-11-01

    CAT-ACT—the hard X-ray beamline for CATalysis and ACTinide/radionuclide research at the KIT synchrotron radiation facility ANKA—is dedicated to X-ray spectroscopy, including "flux hungry" photon-in/photon-out and correlative techniques and combines state-of-the-art optics with a unique infrastructure for radionuclide and catalysis research. Measurements can be performed at photon energies varying between 3.4 keV and 55 keV, thus encompassing the actinide M- and L-edge or potassium K-edge up to the K-edges of the lanthanide series such as cerium. Well-established X-ray absorption fine structure spectroscopy in transmission and fluorescence detection modes is available in combination with high energy-resolution X-ray emission spectroscopy or X-ray diffraction techniques. The modular beamline design with two alternately operated in-line experimental stations enables sufficient flexibility to adapt sample environments and detection systems to many scientific challenges. The ACT experimental station focuses on various aspects of nuclear waste disposal within the mission of the Helmholtz association to contribute to the solution of one of the greatest scientific and social challenges of our time—the safe disposal of heat producing, highly radioactive waste forms from nuclear energy production. It augments present capabilities at the INE-Beamline by increasing the flux and extending the energy range into the hard X-ray regime. The CAT experimental station focuses on catalytic materials, e.g., for energy-related and exhaust gas catalysis. Characterization of catalytically active materials under realistic reaction conditions and the development of in situ and operando cells for sample environments close to industrial reactors are essential aspects at CAT.

  15. Partial QoS-Aware Opportunistic Relay Selection Over Two-Hop Channels: End-to-End Performance Under Spectrum-Sharing Requirements

    KAUST Repository

    Yuli Yang,; Hao Ma,; Aissa, Sonia

    2014-01-01

    it with transmission constraints imposed on the transmit power budget and interference to other users. By analyzing the statistics of received SNRs in the first and second hops, we obtain the end-to-end PLR of this scheme in closed form under the considered scenario

  16. Diamond Beamline I16 (Materials and Magnetism)

    International Nuclear Information System (INIS)

    Collins, S. P.; Bombardi, A.; Marshall, A. R.; Williams, J. H.; Barlow, G.; Day, A. G.; Pearson, M. R.; Woolliscroft, R. J.; Walton, R. D.; Beutier, G.; Nisbet, G.

    2010-01-01

    We describe the key features and performance specifications of a facility for high-resolution single-crystal x-ray diffraction at Diamond Light Source. The scientific emphasis of the beamline is materials- and x-ray-physics, including resonant and magnetic scattering. We highlight some of the more novel aspects of the beamline design.

  17. OpenCyto: an open source infrastructure for scalable, robust, reproducible, and automated, end-to-end flow cytometry data analysis.

    Directory of Open Access Journals (Sweden)

    Greg Finak

    2014-08-01

    Full Text Available Flow cytometry is used increasingly in clinical research for cancer, immunology and vaccines. Technological advances in cytometry instrumentation are increasing the size and dimensionality of data sets, posing a challenge for traditional data management and analysis. Automated analysis methods, despite a general consensus of their importance to the future of the field, have been slow to gain widespread adoption. Here we present OpenCyto, a new BioConductor infrastructure and data analysis framework designed to lower the barrier of entry to automated flow data analysis algorithms by addressing key areas that we believe have held back wider adoption of automated approaches. OpenCyto supports end-to-end data analysis that is robust and reproducible while generating results that are easy to interpret. We have improved the existing, widely used core BioConductor flow cytometry infrastructure by allowing analysis to scale in a memory efficient manner to the large flow data sets that arise in clinical trials, and integrating domain-specific knowledge as part of the pipeline through the hierarchical relationships among cell populations. Pipelines are defined through a text-based csv file, limiting the need to write data-specific code, and are data agnostic to simplify repetitive analysis for core facilities. We demonstrate how to analyze two large cytometry data sets: an intracellular cytokine staining (ICS data set from a published HIV vaccine trial focused on detecting rare, antigen-specific T-cell populations, where we identify a new subset of CD8 T-cells with a vaccine-regimen specific response that could not be identified through manual analysis, and a CyTOF T-cell phenotyping data set where a large staining panel and many cell populations are a challenge for traditional analysis. The substantial improvements to the core BioConductor flow cytometry packages give OpenCyto the potential for wide adoption. It can rapidly leverage new developments in

  18. Including 10-Gigabit-capable Passive Optical Network under End-to-End Generalized Multi-Protocol Label Switching Provisioned Quality of Service

    DEFF Research Database (Denmark)

    Brewka, Lukasz Jerzy; Gavler, Anders; Wessing, Henrik

    2012-01-01

    of the network where quality of service signaling is bridged. This article proposes strategies for generalized multi-protocol label switching control over next emerging passive optical network standard, i.e., the 10-gigabit-capable passive optical network. Node management and resource allocation approaches...... are discussed, and possible issues are raised. The analysis shows that consideration of a 10-gigabit-capable passive optical network as a generalized multi-protocol label switching controlled domain is valid and may advance end-to-end quality of service provisioning for passive optical network based customers.......End-to-end quality of service provisioning is still a challenging task despite many years of research and development in this area. Considering a generalized multi-protocol label switching based core/metro network and resource reservation protocol capable home gateways, it is the access part...

  19. Influence of suture technique and suture material selection on the mechanics of end-to-end and end-to-side anastomoses.

    Science.gov (United States)

    Baumgartner, N; Dobrin, P B; Morasch, M; Dong, Q S; Mrkvicka, R

    1996-05-01

    Experiments were performed in dogs to evaluate the mechanics of 26 end-to-end and 42 end-to-side artery-vein graft anastomoses constructed with continuous polypropylene sutures (Surgilene; Davis & Geck, Division of American Cyanamid Co., Danbury, Conn.), continuous polybutester sutures (Novafil; Davis & Geck), and interrupted stitches with either suture material. After construction, the grafts and adjoining arteries were excised, mounted in vitro at in situ length, filled with a dilute barium sulfate suspension, and pressurized in 25 mm Hg steps up to 200 mm Hg. Radiographs were obtained at each pressure. The computed cross-sectional areas of the anastomoses were compared with those of the native arteries at corresponding pressures. Results showed that for the end-to-end anastomoses at 100 mm Hg the cross-sectional areas of the continuous Surgilene anastomoses were 70% of the native artery cross-sectional areas, the cross-sectional areas of the continuous Novafil anastomoses were 90% of the native artery cross-sectional areas, and the cross-sectional areas of the interrupted anastomoses were 107% of the native artery cross-sectional areas (p anastomoses demonstrated no differences in cross-sectional areas or compliance for the three suture techniques. This suggests that, unlike with end-to-end anastomoses, when constructing an end-to-side anastomosis in patients any of the three suture techniques may be acceptable.

  20. One stage functional end-to-end stapled intestinal anastomosis and resection performed by nonexpert surgeons for the treatment of small intestinal obstruction in 30 dogs.

    Science.gov (United States)

    Jardel, Nicolas; Hidalgo, Antoine; Leperlier, Dimitri; Manassero, Mathieu; Gomes, Aymeric; Bedu, Anne Sophie; Moissonnier, Pierre; Fayolle, Pascal; Begon, Dominique; Riquois, Elisabeth; Viateau, Véronique

    2011-02-01

    To describe stapled 1-stage functional end-to-end intestinal anastomosis for treatment of small intestinal obstruction in dogs and evaluate outcome when the technique is performed by nonexpert surgeons after limited training in the technique. Case series. Dogs (n=30) with intestinal lesions requiring an enterectomy. Stapled 1-stage functional end-to-end anastomosis and resection using a GIA-60 and a TA-55 stapling devices were performed under supervision of senior residents and faculty surgeons by junior surgeons previously trained in the technique on pigs. Procedure duration and technical problems were recorded. Short-term results were collected during hospitalization and at suture removal. Long-term outcome was established by clinical and ultrasonographic examinations at least 2 months after surgery and from written questionnaires, completed by owners. Mean±SD procedure duration was 15±12 minutes. Postoperative recovery was uneventful in 25 dogs. One dog had anastomotic leakage, 1 had a localized abscess at the transverse staple line, and 3 dogs developed an incisional abdominal wall abscess. No long-term complications occurred (follow-up, 2-32 months). Stapled 1-stage functional end-to-end anastomosis and resection is a fast and safe procedure in the hand of nonexpert but trained surgeons. © Copyright 2011 by The American College of Veterinary Surgeons.

  1. Primary and secondary structure dependence of peptide flexibility assessed by fluorescence-based measurement of end-to-end collision rates.

    Science.gov (United States)

    Huang, Fang; Hudgins, Robert R; Nau, Werner M

    2004-12-22

    The intrachain fluorescence quenching of the fluorophore 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) is measured in short peptide fragments, namely the two strands and the turn of the N-terminal beta-hairpin of ubiquitin. The investigated peptides adopt a random-coil conformation in aqueous solution according to CD and NMR experiments. The combination of quenchers with different quenching efficiencies, namely tryptophan and tyrosine, allows the extrapolation of the rate constants for end-to-end collision rates as well as the dissociation of the end-to-end encounter complex. The measured activation energies for fluorescence quenching demonstrate that the end-to-end collision process in peptides is partially controlled by internal friction within the backbone, while measurements in solvents of different viscosities (H2O, D2O, and 7.0 M guanidinium chloride) suggest that solvent friction is an additional important factor in determining the collision rate. The extrapolated end-to-end collision rates, which are only slightly larger than the experimental rates for the DBO/Trp probe/quencher system, provide a measure of the conformational flexibility of the peptide backbone. The chain flexibility is found to be strongly dependent on the type of secondary structure that the peptides represent. The collision rates for peptides derived from the beta-strand motifs (ca. 1 x 10(7) s(-1)) are ca. 4 times slower than that derived from the beta-turn. The results provide further support for the hypothesis that chain flexibility is an important factor in the preorganization of protein fragments during protein folding. Mutations to the beta-turn peptide show that subtle sequence changes strongly affect the flexibility of peptides as well. The protonation and charge status of the peptides, however, are shown to have no significant effect on the flexibility of the investigated peptides. The meaning and definition of end-to-end collision rates in the context of protein folding are critically

  2. A fully automatic end-to-end method for content-based image retrieval of CT scans with similar liver lesion annotations.

    Science.gov (United States)

    Spanier, A B; Caplan, N; Sosna, J; Acar, B; Joskowicz, L

    2018-01-01

    The goal of medical content-based image retrieval (M-CBIR) is to assist radiologists in the decision-making process by retrieving medical cases similar to a given image. One of the key interests of radiologists is lesions and their annotations, since the patient treatment depends on the lesion diagnosis. Therefore, a key feature of M-CBIR systems is the retrieval of scans with the most similar lesion annotations. To be of value, M-CBIR systems should be fully automatic to handle large case databases. We present a fully automatic end-to-end method for the retrieval of CT scans with similar liver lesion annotations. The input is a database of abdominal CT scans labeled with liver lesions, a query CT scan, and optionally one radiologist-specified lesion annotation of interest. The output is an ordered list of the database CT scans with the most similar liver lesion annotations. The method starts by automatically segmenting the liver in the scan. It then extracts a histogram-based features vector from the segmented region, learns the features' relative importance, and ranks the database scans according to the relative importance measure. The main advantages of our method are that it fully automates the end-to-end querying process, that it uses simple and efficient techniques that are scalable to large datasets, and that it produces quality retrieval results using an unannotated CT scan. Our experimental results on 9 CT queries on a dataset of 41 volumetric CT scans from the 2014 Image CLEF Liver Annotation Task yield an average retrieval accuracy (Normalized Discounted Cumulative Gain index) of 0.77 and 0.84 without/with annotation, respectively. Fully automatic end-to-end retrieval of similar cases based on image information alone, rather that on disease diagnosis, may help radiologists to better diagnose liver lesions.

  3. Experience of using MOSFET detectors for dose verification measurements in an end-to-end 192Ir brachytherapy quality assurance system.

    Science.gov (United States)

    Persson, Maria; Nilsson, Josef; Carlsson Tedgren, Åsa

    Establishment of an end-to-end system for the brachytherapy (BT) dosimetric chain could be valuable in clinical quality assurance. Here, the development of such a system using MOSFET (metal oxide semiconductor field effect transistor) detectors and experience gained during 2 years of use are reported with focus on the performance of the MOSFET detectors. A bolus phantom was constructed with two implants, mimicking prostate and head & neck treatments, using steel needles and plastic catheters to guide the 192 Ir source and house the MOSFET detectors. The phantom was taken through the BT treatment chain from image acquisition to dose evaluation. During the 2-year evaluation-period, delivered doses were verified a total of 56 times using MOSFET detectors which had been calibrated in an external 60 Co beam. An initial experimental investigation on beam quality differences between 192 Ir and 60 Co is reported. The standard deviation in repeated MOSFET measurements was below 3% in the six measurement points with dose levels above 2 Gy. MOSFET measurements overestimated treatment planning system doses by 2-7%. Distance-dependent experimental beam quality correction factors derived in a phantom of similar size as that used for end-to-end tests applied on a time-resolved measurement improved the agreement. MOSFET detectors provide values stable over time and function well for use as detectors for end-to-end quality assurance purposes in 192 Ir BT. Beam quality correction factors should address not only distance from source but also phantom dimensions. Copyright © 2017 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  4. Interoperable End-to-End Remote Patient Monitoring Platform Based on IEEE 11073 PHD and ZigBee Health Care Profile.

    Science.gov (United States)

    Clarke, Malcolm; de Folter, Joost; Verma, Vivek; Gokalp, Hulya

    2018-05-01

    This paper describes the implementation of an end-to-end remote monitoring platform based on the IEEE 11073 standards for personal health devices (PHD). It provides an overview of the concepts and approaches and describes how the standard has been optimized for small devices with limited resources of processor, memory, and power that use short-range wireless technology. It explains aspects of IEEE 11073, including the domain information model, state model, and nomenclature, and how these support its plug-and-play architecture. It shows how these aspects underpin a much larger ecosystem of interoperable devices and systems that include IHE PCD-01, HL7, and BlueTooth LE medical devices, and the relationship to the Continua Guidelines, advocating the adoption of data standards and nomenclature to support semantic interoperability between health and ambient assisted living in future platforms. The paper further describes the adaptions that have been made in order to implement the standard on the ZigBee Health Care Profile and the experiences of implementing an end-to-end platform that has been deployed to frail elderly patients with chronic disease(s) and patients with diabetes.

  5. User-oriented end-to-end transport protocols for the real-time distribution of telemetry data from NASA spacecraft

    Science.gov (United States)

    Hooke, A. J.

    1979-01-01

    A set of standard telemetry protocols for downlink data flow facilitating the end-to-end transport of instrument data from the spacecraft to the user in real time is proposed. The direct switching of data by autonomous message 'packets' that are assembled by the source instrument on the spacecraft is discussed. The data system consists thus of a format on a message rather than word basis, and such packet telemetry would include standardized protocol headers. Standards are being developed within the NASA End-to-End Data System (NEEDS) program for the source packet and transport frame protocols. The source packet protocol contains identification of both the sequence number of the packet as it is generated by the source and the total length of the packet, while the transport frame protocol includes a sequence count defining the serial number of the frame as it is generated by the spacecraft data system, and a field specifying any 'options' selected in the format of the frame itself.

  6. Ferromagnetic interaction in an asymmetric end-to-end azido double-bridged copper(II) dinuclear complex: a combined structure, magnetic, polarized neutron diffraction and theoretical study.

    Science.gov (United States)

    Aronica, Christophe; Jeanneau, Erwann; El Moll, Hani; Luneau, Dominique; Gillon, Béatrice; Goujon, Antoine; Cousson, Alain; Carvajal, Maria Angels; Robert, Vincent

    2007-01-01

    A new end-to-end azido double-bridged copper(II) complex [Cu(2)L(2)(N(3))2] (1) was synthesized and characterized (L=1,1,1-trifluoro-7-(dimethylamino)-4-methyl-5-aza-3-hepten-2-onato). Despite the rather long Cu-Cu distance (5.105(1) A), the magnetic interaction is ferromagnetic with J= +16 cm(-1) (H=-JS(1)S(2)), a value that has been confirmed by DFT and high-level correlated ab initio calculations. The spin distribution was studied by using the results from polarized neutron diffraction. This is the first such study on an end-to-end system. The experimental spin density was found to be localized mainly on the copper(II) ions, with a small degree of delocalization on the ligand (L) and terminal azido nitrogens. There was zero delocalization on the central nitrogen, in agreement with DFT calculations. Such a picture corresponds to an important contribution of the d(x2-y2) orbital and a small population of the d(z2) orbital, in agreement with our calculations. Based on a correlated wavefunction analysis, the ferromagnetic behavior results from a dominant double spin polarization contribution and vanishingly small ionic forms.

  7. The Upgrade Programme for the Structural Biology beamlines at the European Synchrotron Radiation Facility - High throughput sample evaluation and automation

    Science.gov (United States)

    Theveneau, P.; Baker, R.; Barrett, R.; Beteva, A.; Bowler, M. W.; Carpentier, P.; Caserotto, H.; de Sanctis, D.; Dobias, F.; Flot, D.; Guijarro, M.; Giraud, T.; Lentini, M.; Leonard, G. A.; Mattenet, M.; McCarthy, A. A.; McSweeney, S. M.; Morawe, C.; Nanao, M.; Nurizzo, D.; Ohlsson, S.; Pernot, P.; Popov, A. N.; Round, A.; Royant, A.; Schmid, W.; Snigirev, A.; Surr, J.; Mueller-Dieckmann, C.

    2013-03-01

    Automation and advances in technology are the key elements in addressing the steadily increasing complexity of Macromolecular Crystallography (MX) experiments. Much of this complexity is due to the inter-and intra-crystal heterogeneity in diffraction quality often observed for crystals of multi-component macromolecular assemblies or membrane proteins. Such heterogeneity makes high-throughput sample evaluation an important and necessary tool for increasing the chances of a successful structure determination. The introduction at the ESRF of automatic sample changers in 2005 dramatically increased the number of samples that were tested for diffraction quality. This "first generation" of automation, coupled with advances in software aimed at optimising data collection strategies in MX, resulted in a three-fold increase in the number of crystal structures elucidated per year using data collected at the ESRF. In addition, sample evaluation can be further complemented using small angle scattering experiments on the newly constructed bioSAXS facility on BM29 and the micro-spectroscopy facility (ID29S). The construction of a second generation of automated facilities on the MASSIF (Massively Automated Sample Screening Integrated Facility) beam lines will build on these advances and should provide a paradigm shift in how MX experiments are carried out which will benefit the entire Structural Biology community.

  8. Mixed integer nonlinear programming model of wireless pricing scheme with QoS attribute of bandwidth and end-to-end delay

    Science.gov (United States)

    Irmeilyana, Puspita, Fitri Maya; Indrawati

    2016-02-01

    The pricing for wireless networks is developed by considering linearity factors, elasticity price and price factors. Mixed Integer Nonlinear Programming of wireless pricing model is proposed as the nonlinear programming problem that can be solved optimally using LINGO 13.0. The solutions are expected to give some information about the connections between the acceptance factor and the price. Previous model worked on the model that focuses on bandwidth as the QoS attribute. The models attempt to maximize the total price for a connection based on QoS parameter. The QoS attributes used will be the bandwidth and the end to end delay that affect the traffic. The maximum goal to maximum price is achieved when the provider determine the requirement for the increment or decrement of price change due to QoS change and amount of QoS value.

  9. Crystal structure of Aquifex aeolicus gene product Aq1627: a putative phosphoglucosamine mutase reveals a unique C-terminal end-to-end disulfide linkage.

    Science.gov (United States)

    Sridharan, Upasana; Kuramitsu, Seiki; Yokoyama, Shigeyuki; Kumarevel, Thirumananseri; Ponnuraj, Karthe

    2017-06-27

    The Aq1627 gene from Aquifex aeolicus, a hyperthermophilic bacterium has been cloned and overexpressed in Escherichia coli. The protein was purified to homogeneity and its X-ray crystal structure was determined to 1.3 Å resolution using multiple wavelength anomalous dispersion phasing. The structural and sequence analysis of Aq1627 is suggestive of a putative phosphoglucosamine mutase. The structural features of Aq1627 further indicate that it could belong to a new subclass of the phosphoglucosamine mutase family. Aq1627 structure contains a unique C-terminal end-to-end disulfide bond, which links two monomers and this structural information can be used in protein engineering to make proteins more stable in different applications.

  10. Reconstruction after ureteral resection during HIPEC surgery: Re-implantation with uretero-neocystostomy seems safer than end-to-end anastomosis.

    Science.gov (United States)

    Pinar, U; Tremblay, J-F; Passot, G; Dazza, M; Glehen, O; Tuech, J-J; Pocard, M

    2017-09-01

    Resection of the pelvic ureter may be necessary in cytoreductive surgery for peritoneal carcinomatosis in combination with hyperthermic intraperitoneal chemotherapy (HIPEC). As the morbidity for cytoreductive surgery with HIPEC has decreased, expert teams have begun to perform increasingly complex surgical procedures associated with HIPEC, including pelvic reconstructions. After ureteral resection, two types of reconstruction are possible: uretero-ureteral end-to-end anastomosis and uretero-vesical re-implantation or uretero-neocystostomy (the so-called psoas hitch technique). By compiling the experience of three surgical teams that perform HIPEC surgeries, we have tried to compare the effectiveness of these two techniques. A retrospective comparative case-matched multicenter study was conducted for patients undergoing operation between 2005 and 2014. Patients included had undergone resection of the pelvic ureter during cytoreductive surgery with HIPEC for peritoneal carcinomatomosis; ureteral reconstruction was by either end-to-end anastomosis (EEA group) or re-implantation uretero-neocystostomy (RUC group). The primary endpoint was the occurrence of urinary fistula in postoperative follow-up. There were 14 patients in the EEA group and 14 in the RUC group. The groups were comparable for age, extent of carcinomatosis (PCI index) and operative duration. Four urinary fistulas occurred in the EEA group (28.5%) versus zero fistulas in the RUC group (0%) (P=0.0308). Re-implantation with uretero-neocystostomy during cytoreductive surgery with HIPEC is the preferred technique for reconstruction after ureteral resection in case of renal conservation. Copyright © 2017. Published by Elsevier Masson SAS.

  11. Poster - 44: Development and implementation of a comprehensive end-to-end testing methodology for linac-based frameless SRS QA using a modified commercial stereotactic anthropomorphic phantom

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Derek; Mutanga, Theodore [University of Toronto, Carlo Fidani Peel Regional Cancer Center (Canada)

    2016-08-15

    Purpose: An end-to-end testing methodology was designed to evaluate the overall SRS treatment fidelity, incorporating all steps in the linac-based frameless radiosurgery treatment delivery process. The study details our commissioning experience of the Steev (CIRS, Norfolk, VA) stereotactic anthropomorphic head phantom including modification, test design, and baseline measurements. Methods: Repeated MR and CT scans were performed with interchanging inserts. MR-CT fusion accuracy was evaluated and the insert spatial coincidence was verified on CT. Five non-coplanar arcs delivered a prescription dose to a 15 mm spherical CTV with 2 mm PTV margin. Following setup, CBCT-based shifts were applied as per protocol. Sequential measurements were performed by interchanging inserts without disturbing the setup. Spatial and dosimetric accuracy was assessed by a combination of CBCT hidden target, radiochromic film, and ion chamber measurements. To facilitate film registration, the film insert was modified in-house by etching marks. Results: MR fusion error and insert spatial coincidences were within 0.3 mm. Both CBCT and film measurements showed spatial displacements of 1.0 mm in similar directions. Both coronal and sagittal films reported 2.3 % higher target dose relative to the treatment plan. The corrected ion chamber measurement was similarly greater by 1.0 %. The 3 %/2 mm gamma pass rate was 99% for both films Conclusions: A comprehensive end-to-end testing methodology was implemented for our SRS QA program. The Steev phantom enabled realistic evaluation of the entire treatment process. Overall spatial and dosimetric accuracy of the delivery were 1 mm and 3 % respectively.

  12. A Validation Approach of an End-to-End Whole Genome Sequencing Workflow for Source Tracking of Listeria monocytogenes and Salmonella enterica

    Directory of Open Access Journals (Sweden)

    Anne-Catherine Portmann

    2018-03-01

    Full Text Available Whole genome sequencing (WGS, using high throughput sequencing technology, reveals the complete sequence of the bacterial genome in a few days. WGS is increasingly being used for source tracking, pathogen surveillance and outbreak investigation due to its high discriminatory power. In the food industry, WGS used for source tracking is beneficial to support contamination investigations. Despite its increased use, no standards or guidelines are available today for the use of WGS in outbreak and/or trace-back investigations. Here we present a validation of our complete (end-to-end WGS workflow for Listeria monocytogenes and Salmonella enterica including: subculture of isolates, DNA extraction, sequencing and bioinformatics analysis. This end-to-end WGS workflow was evaluated according to the following performance criteria: stability, repeatability, reproducibility, discriminatory power, and epidemiological concordance. The current study showed that few single nucleotide polymorphism (SNPs were observed for L. monocytogenes and S. enterica when comparing genome sequences from five independent colonies from the first subculture and five independent colonies after the tenth subculture. Consequently, the stability of the WGS workflow for L. monocytogenes and S. enterica was demonstrated despite the few genomic variations that can occur during subculturing steps. Repeatability and reproducibility were also demonstrated. The WGS workflow was shown to have a high discriminatory power and has the ability to show genetic relatedness. Additionally, the WGS workflow was able to reproduce published outbreak investigation results, illustrating its capability of showing epidemiological concordance. The current study proposes a validation approach comprising all steps of a WGS workflow and demonstrates that the workflow can be applied to L. monocytogenes or S. enterica.

  13. SU-F-T-76: Total Skin Electron Therapy: An-End-To-End Examination of the Absolute Dosimetry with a Rando Phantom

    Energy Technology Data Exchange (ETDEWEB)

    Cui, G; Ha, J; Zhou, S; Cui, J; Shiu, A [University Southern California, Los Angeles, CA (United States)

    2016-06-15

    Purpose: To examine and validate the absolute dose for total skin electron therapy (TSET) through an end-to-end test with a Rando phantom using optically stimulated luminescent dosimeters (OSLDs) and EBT3 radiochromic films. Methods: A Varian Trilogy linear accelerator equipped with the special procedure 6 MeV HDTSe- was used to perform TSET irradiations using a modified Stanford 6-dual-field technique. The absolute dose was calibrated using a Markus ion chamber at a reference depth of 1.3cm at 100 cm SSD with a field size of 36 × 36 cm at the isocenter in solid water slabs. The absolute dose was cross validated by a farmer ion chamber. Then the dose rate in the unit of cGy/Mu was calibrated using the Markus chamber at the treatment position. OSLDs were used to independently verify the dose using the calibrated dose rate. Finally, a patient treatment plan (200 cGy/cycle) was delivered in the QA mode to a Rando phantom, which had 16 pairs of OSLDs and EBT3 films taped onto its surface at different anatomical positions. The doses recorded were read out to validate the absolute dosimetry for TSET. Results: The OSLD measurements were within 7% agreement with the planned dose except the shoulder areas, where the doses recorded were 23% lower on average than those of the planned. The EBT3 film measurements were within 10% agreement with the planned dose except the shoulder and the scalp vertex areas, where the respective doses recorded were 18% and 14% lower on average than those of the planned. The OSLDs gave more consistent dose measurements than those of the EBT3 films. Conclusion: The absolute dosimetry for TSET was validated by an end-to-end test with a Rando phantom using the OSLDs and EBT3 films. The beam calibration and monitor unit calculations were confirmed.

  14. Human factors design for the BMIT biomedical beamlines

    International Nuclear Information System (INIS)

    Miller, C Denise; Wysokinski, Tomasz W; Belev, George; Chapman, L Dean

    2013-01-01

    Operation of a biomedical beamline poses a unique set of operational and instrumentation challenges for a synchrotron facility. From proper handling and care of live animals and animal tissues, to a user community drawn primarily from the medical and veterinary realms, the work of a biomedical beamline is unique when compared to other beamlines. At the Biomedical Imaging and Therapy (BMIT) beamlines at Canadian Light Source (CLS), operation of the beamlines is geared towards our user community of medical personnel, in addition to basic science researchers. Human factors considerations have been incorporated wherever possible on BMIT, including in the design of software and hardware, as well as ease-of-use features of beamline control stations and experiment hutches. Feedback from users continues to drive usability improvements to beamline operations.

  15. Imaging and dosimetric errors in 4D PET/CT-guided radiotherapy from patient-specific respiratory patterns: a dynamic motion phantom end-to-end study.

    Science.gov (United States)

    Bowen, S R; Nyflot, M J; Herrmann, C; Groh, C M; Meyer, J; Wollenweber, S D; Stearns, C W; Kinahan, P E; Sandison, G A

    2015-05-07

    Effective positron emission tomography / computed tomography (PET/CT) guidance in radiotherapy of lung cancer requires estimation and mitigation of errors due to respiratory motion. An end-to-end workflow was developed to measure patient-specific motion-induced uncertainties in imaging, treatment planning, and radiation delivery with respiratory motion phantoms and dosimeters. A custom torso phantom with inserts mimicking normal lung tissue and lung lesion was filled with [(18)F]FDG. The lung lesion insert was driven by six different patient-specific respiratory patterns or kept stationary. PET/CT images were acquired under motionless ground truth, tidal breathing motion-averaged (3D), and respiratory phase-correlated (4D) conditions. Target volumes were estimated by standardized uptake value (SUV) thresholds that accurately defined the ground-truth lesion volume. Non-uniform dose-painting plans using volumetrically modulated arc therapy were optimized for fixed normal lung and spinal cord objectives and variable PET-based target objectives. Resulting plans were delivered to a cylindrical diode array at rest, in motion on a platform driven by the same respiratory patterns (3D), or motion-compensated by a robotic couch with an infrared camera tracking system (4D). Errors were estimated relative to the static ground truth condition for mean target-to-background (T/Bmean) ratios, target volumes, planned equivalent uniform target doses, and 2%-2 mm gamma delivery passing rates. Relative to motionless ground truth conditions, PET/CT imaging errors were on the order of 10-20%, treatment planning errors were 5-10%, and treatment delivery errors were 5-30% without motion compensation. Errors from residual motion following compensation methods were reduced to 5-10% in PET/CT imaging, PET/CT imaging to RT planning, and RT delivery under a dose painting paradigm is feasible within an integrated respiratory motion phantom workflow. For a limited set of cases, the magnitude

  16. Imaging and dosimetric errors in 4D PET/CT-guided radiotherapy from patient-specific respiratory patterns: a dynamic motion phantom end-to-end study

    International Nuclear Information System (INIS)

    Bowen, S R; Nyflot, M J; Meyer, J; Sandison, G A; Herrmann, C; Groh, C M; Wollenweber, S D; Stearns, C W; Kinahan, P E

    2015-01-01

    Effective positron emission tomography / computed tomography (PET/CT) guidance in radiotherapy of lung cancer requires estimation and mitigation of errors due to respiratory motion. An end-to-end workflow was developed to measure patient-specific motion-induced uncertainties in imaging, treatment planning, and radiation delivery with respiratory motion phantoms and dosimeters. A custom torso phantom with inserts mimicking normal lung tissue and lung lesion was filled with [ 18 F]FDG. The lung lesion insert was driven by six different patient-specific respiratory patterns or kept stationary. PET/CT images were acquired under motionless ground truth, tidal breathing motion-averaged (3D), and respiratory phase-correlated (4D) conditions. Target volumes were estimated by standardized uptake value (SUV) thresholds that accurately defined the ground-truth lesion volume. Non-uniform dose-painting plans using volumetrically modulated arc therapy were optimized for fixed normal lung and spinal cord objectives and variable PET-based target objectives. Resulting plans were delivered to a cylindrical diode array at rest, in motion on a platform driven by the same respiratory patterns (3D), or motion-compensated by a robotic couch with an infrared camera tracking system (4D). Errors were estimated relative to the static ground truth condition for mean target-to-background (T/B mean ) ratios, target volumes, planned equivalent uniform target doses, and 2%-2 mm gamma delivery passing rates. Relative to motionless ground truth conditions, PET/CT imaging errors were on the order of 10–20%, treatment planning errors were 5–10%, and treatment delivery errors were 5–30% without motion compensation. Errors from residual motion following compensation methods were reduced to 5–10% in PET/CT imaging, <5% in treatment planning, and <2% in treatment delivery. We have demonstrated that estimation of respiratory motion uncertainty and its propagation from PET/CT imaging to RT

  17. Imaging and dosimetric errors in 4D PET/CT-guided radiotherapy from patient-specific respiratory patterns: a dynamic motion phantom end-to-end study

    Science.gov (United States)

    Bowen, S R; Nyflot, M J; Hermann, C; Groh, C; Meyer, J; Wollenweber, S D; Stearns, C W; Kinahan, P E; Sandison, G A

    2015-01-01

    Effective positron emission tomography/computed tomography (PET/CT) guidance in radiotherapy of lung cancer requires estimation and mitigation of errors due to respiratory motion. An end-to-end workflow was developed to measure patient-specific motion-induced uncertainties in imaging, treatment planning, and radiation delivery with respiratory motion phantoms and dosimeters. A custom torso phantom with inserts mimicking normal lung tissue and lung lesion was filled with [18F]FDG. The lung lesion insert was driven by 6 different patient-specific respiratory patterns or kept stationary. PET/CT images were acquired under motionless ground truth, tidal breathing motion-averaged (3D), and respiratory phase-correlated (4D) conditions. Target volumes were estimated by standardized uptake value (SUV) thresholds that accurately defined the ground-truth lesion volume. Non-uniform dose-painting plans using volumetrically modulated arc therapy (VMAT) were optimized for fixed normal lung and spinal cord objectives and variable PET-based target objectives. Resulting plans were delivered to a cylindrical diode array at rest, in motion on a platform driven by the same respiratory patterns (3D), or motion-compensated by a robotic couch with an infrared camera tracking system (4D). Errors were estimated relative to the static ground truth condition for mean target-to-background (T/Bmean) ratios, target volumes, planned equivalent uniform target doses (EUD), and 2%-2mm gamma delivery passing rates. Relative to motionless ground truth conditions, PET/CT imaging errors were on the order of 10–20%, treatment planning errors were 5–10%, and treatment delivery errors were 5–30% without motion compensation. Errors from residual motion following compensation methods were reduced to 5–10% in PET/CT imaging, PET/CT imaging to RT planning, and RT delivery under a dose painting paradigm is feasible within an integrated respiratory motion phantom workflow. For a limited set of cases, the

  18. Presence of calcium in the vessel walls after end-to-end arterial anastomoses with polydioxanone and polypropylene sutures in growing dogs.

    Science.gov (United States)

    Gersak, B

    1993-10-01

    The presence of calcium in the vessel walls after end-to-end arterial anastomoses performed with polydioxanone and polypropylene interrupted sutures was studied in 140 anastomoses in 35 10-week-old German shepherd dogs. Histologic examination with hematoxylin and eosin, van Gieson, and von Kossa staining techniques was performed after the animals were killed 6 months after the operation. Ketamine hydrochloride was used as an anesthetic agent. At the start of the investigation the dogs weighed 14.5 +/- 2.6 kg (mean +/- standard deviation, n = 35), and after 6 months they weighed 45.3 +/- 3.1 kg (mean +/- standard deviation, n = 35). The diameter of the sutured arteries in the first operation was 2.6 +/- 0.5 mm (mean +/- standard deviation, n = 140). With each dog, both brachial and both femoral arteries were used--one artery for each different type of suture. In different dogs, different arteries were used for the same type of suture. The prevalence of calcifications after 6 months was determined from the numeric density of calcifications with standard stereologic techniques. The sutured and sutureless parts taken from longitudinal sections from each artery were studied, and t test values were calculated as follows: In paired samples, statistically significant differences in numerical density of calcifications were seen between sutured and sutureless arterial parts for both materials (sutureless part versus part with polydioxanone sutures, p 0.05, n = 70) and sutureless parts (p > 0.05, n = 70).

  19. Poly(ethyl glyoxylate)-Poly(ethylene oxide) Nanoparticles: Stimuli-Responsive Drug Release via End-to-End Polyglyoxylate Depolymerization.

    Science.gov (United States)

    Fan, Bo; Gillies, Elizabeth R

    2017-08-07

    The ability to disrupt polymer assemblies in response to specific stimuli provides the potential to release drugs selectively at certain sites or conditions in vivo. However, most stimuli-responsive delivery systems require many stimuli-initiated events to release drugs. "Self-immolative polymers" offer the potential to provide amplified responses to stimuli as they undergo complete end-to-end depolymerization following the cleavage of a single end-cap. Herein, linker end-caps were developed to conjugate self-immolative poly(ethyl glyoxylate) (PEtG) with poly(ethylene oxide) (PEO) to form amphiphilic block copolymers. These copolymers were self-assembled to form nanoparticles in aqueous solution. Cleavage of the linker end-caps were triggered by a thiol reducing agent, UV light, H 2 O 2 , and combinations of these stimuli, resulting in nanoparticle disintegration. Low stimuli concentrations were effective in rapidly disrupting the nanoparticles. Nile red, doxorubin, and curcumin were encapsulated into the nanoparticles and were selectively released upon application of the appropriate stimulus. The ability to tune the stimuli-responsiveness simply by changing the linker end-cap makes this new platform highly attractive for applications in drug delivery.

  20. System for Informatics in the Molecular Pathology Laboratory: An Open-Source End-to-End Solution for Next-Generation Sequencing Clinical Data Management.

    Science.gov (United States)

    Kang, Wenjun; Kadri, Sabah; Puranik, Rutika; Wurst, Michelle N; Patil, Sushant A; Mujacic, Ibro; Benhamed, Sonia; Niu, Nifang; Zhen, Chao Jie; Ameti, Bekim; Long, Bradley C; Galbo, Filipo; Montes, David; Iracheta, Crystal; Gamboa, Venessa L; Lopez, Daisy; Yourshaw, Michael; Lawrence, Carolyn A; Aisner, Dara L; Fitzpatrick, Carrie; McNerney, Megan E; Wang, Y Lynn; Andrade, Jorge; Volchenboum, Samuel L; Furtado, Larissa V; Ritterhouse, Lauren L; Segal, Jeremy P

    2018-04-24

    Next-generation sequencing (NGS) diagnostic assays increasingly are becoming the standard of care in oncology practice. As the scale of an NGS laboratory grows, management of these assays requires organizing large amounts of information, including patient data, laboratory processes, genomic data, as well as variant interpretation and reporting. Although several Laboratory Information Systems and/or Laboratory Information Management Systems are commercially available, they may not meet all of the needs of a given laboratory, in addition to being frequently cost-prohibitive. Herein, we present the System for Informatics in the Molecular Pathology Laboratory, a free and open-source Laboratory Information System/Laboratory Information Management System for academic and nonprofit molecular pathology NGS laboratories, developed at the Genomic and Molecular Pathology Division at the University of Chicago Medicine. The System for Informatics in the Molecular Pathology Laboratory was designed as a modular end-to-end information system to handle all stages of the NGS laboratory workload from test order to reporting. We describe the features of the system, its clinical validation at the Genomic and Molecular Pathology Division at the University of Chicago Medicine, and its installation and testing within a different academic center laboratory (University of Colorado), and we propose a platform for future community co-development and interlaboratory data sharing. Copyright © 2018. Published by Elsevier Inc.

  1. Partial QoS-Aware Opportunistic Relay Selection Over Two-Hop Channels: End-to-End Performance Under Spectrum-Sharing Requirements

    KAUST Repository

    Yuli Yang,

    2014-10-01

    In this paper, we propose a partial quality-of-service (QoS)-oriented relay selection scheme with a decode-and-forward (DF) relaying protocol, to reduce the feedback amount required for relay selection. In the proposed scheme, the activated relay is the one with the maximum signal-to-noise power ratio (SNR) in the second hop among those whose packet loss rates (PLRs) in the first hop achieve a predetermined QoS level. For the purpose of evaluating the performance of the proposed scheme, we exploit it with transmission constraints imposed on the transmit power budget and interference to other users. By analyzing the statistics of received SNRs in the first and second hops, we obtain the end-to-end PLR of this scheme in closed form under the considered scenario. Moreover, to compare the proposed scheme with popular relay selection schemes, we also derive the closed-form PLR expressions for partial relay selection (PRS) and opportunistic relay selection (ORS) criteria in the same scenario under study. Illustrative numerical results demonstrate the accuracy of our derivations and substantiate that the proposed relay selection scheme is a promising alternative with respect to the tradeoff between performance and complexity.

  2. Albert-Lembert versus hybrid-layered suture in hand sewn end-to-end cervical esophagogastric anastomosis after esophageal squamous cell carcinoma resection.

    Science.gov (United States)

    Feng, Fan; Sun, Li; Xu, Guanghui; Hong, Liu; Yang, Jianjun; Cai, Lei; Li, Guocai; Guo, Man; Lian, Xiao; Zhang, Hongwei

    2015-11-01

    Hand sewn cervical esophagogastric anastomosis (CEGA) is regarded as preferred technique by surgeons after esophagectomy. However, considering the anastomotic leakage and stricture, the optimal technique for performing this anastomosis is still under debate. Between November 2010 and September 2012, 230 patients who underwent esophagectomy with hand sewn end-to-end (ETE) CEGA for esophageal squamous cell carcinoma (ESCC) were analyzed retrospectively, including 111 patients underwent Albert-Lembert suture anastomosis and 119 patients underwent hybrid-layered suture anastomosis. Anastomosis construction time was recorded during operation. Anastomotic leakage was recorded through upper gastrointestinal water-soluble contrast examination. Anastomotic stricture was recorded during follow up. The hybrid-layered suture was faster than Albert-Lembert suture (29.40±1.24 min vs. 33.83±1.41 min, P=0.02). The overall anastomotic leak rate was 7.82%, the leak rate in hybrid-layered suture group was significantly lower than that in Albert-Lembert suture group (3.36% vs. 12.61%, P=0.01). The overall anastomotic stricture rate was 9.13%, the stricture rate in hybrid-layered suture group was significantly lower than that in Albert-Lembert suture group (5.04% vs. 13.51%, P=0.04). Hand sewn ETE CEGA with hybrid-layered suture is associated with lower anastomotic leakage and stricture rate compared to hand sewn ETE CEGA with Albert-Lembert suture.

  3. Stapled side-to-side anastomosis might be better than handsewn end-to-end anastomosis in ileocolic resection for Crohn's disease: a meta-analysis.

    Science.gov (United States)

    He, Xiaosheng; Chen, Zexian; Huang, Juanni; Lian, Lei; Rouniyar, Santosh; Wu, Xiaojian; Lan, Ping

    2014-07-01

    Ileocolic anastomosis is an essential step in the treatment to restore continuity of the gastrointestinal tract following ileocolic resection in patients with Crohn's disease (CD). However, the association between anastomotic type and surgical outcome is controversial. The aim of this meta-analysis is to compare surgical outcomes between stapled side-to-side anastomosis (SSSA) and handsewn end-to-end anastomosis (HEEA) after ileocolic resection in patients with CD. Studies comparing SSSA with HEEA after ileocolic resection in patients with CD were identified in PubMed and EMBASE. Outcomes such as complication, recurrence, and re-operation were evaluated. Eight studies (three randomized controlled trials, one prospective non-randomized trial, and four non-randomized retrospective trials) comparing SSSA (396 cases) and HEEA (425 cases) were included. As compared with HEEA, SSSA was superior in terms of overall postoperative complications [odds ratio (OR), 0.54; 95 % confidence interval (CI) 0.32-0.93], anastomotic leak (OR 0.45; 95 % CI 0.20-1.00), recurrence (OR 0.20; 95 % CI 0.07-0.55), and re-operation for recurrence (OR 0.18; 95 % CI 0.07-0.45). Postoperative hospital stay, mortality, and complications other than anastomotic leak were comparable. Based on the results of our meta-analysis, SSSA would appear to be the preferred procedure after ileocolic resection for CD, with reduced overall postoperative complications, especially anastomotic leak, and a decreased recurrence and re-operation rate.

  4. Distributed Large Data-Object Environments: End-to-End Performance Analysis of High Speed Distributed Storage Systems in Wide Area ATM Networks

    Science.gov (United States)

    Johnston, William; Tierney, Brian; Lee, Jason; Hoo, Gary; Thompson, Mary

    1996-01-01

    We have developed and deployed a distributed-parallel storage system (DPSS) in several high speed asynchronous transfer mode (ATM) wide area networks (WAN) testbeds to support several different types of data-intensive applications. Architecturally, the DPSS is a network striped disk array, but is fairly unique in that its implementation allows applications complete freedom to determine optimal data layout, replication and/or coding redundancy strategy, security policy, and dynamic reconfiguration. In conjunction with the DPSS, we have developed a 'top-to-bottom, end-to-end' performance monitoring and analysis methodology that has allowed us to characterize all aspects of the DPSS operating in high speed ATM networks. In particular, we have run a variety of performance monitoring experiments involving the DPSS in the MAGIC testbed, which is a large scale, high speed, ATM network and we describe our experience using the monitoring methodology to identify and correct problems that limit the performance of high speed distributed applications. Finally, the DPSS is part of an overall architecture for using high speed, WAN's for enabling the routine, location independent use of large data-objects. Since this is part of the motivation for a distributed storage system, we describe this architecture.

  5. SPring-8 beamline control system.

    Science.gov (United States)

    Ohata, T; Konishi, H; Kimura, H; Furukawa, Y; Tamasaku, K; Nakatani, T; Tanabe, T; Matsumoto, N; Ishii, M; Ishikawa, T

    1998-05-01

    The SPring-8 beamline control system is now taking part in the control of the insertion device (ID), front end, beam transportation channel and all interlock systems of the beamline: it will supply a highly standardized environment of apparatus control for collaborative researchers. In particular, ID operation is very important in a third-generation synchrotron light source facility. It is also very important to consider the security system because the ID is part of the storage ring and is therefore governed by the synchrotron ring control system. The progress of computer networking systems and the technology of security control require the development of a highly flexible control system. An interlock system that is independent of the control system has increased the reliability. For the beamline control system the so-called standard model concept has been adopted. VME-bus (VME) is used as the front-end control system and a UNIX workstation as the operator console. CPU boards of the VME-bus are RISC processor-based board computers operated by a LynxOS-based HP-RT real-time operating system. The workstation and the VME are linked to each other by a network, and form the distributed system. The HP 9000/700 series with HP-UX and the HP 9000/743rt series with HP-RT are used. All the controllable apparatus may be operated from any workstation.

  6. An end-to-end examination of geometric accuracy of IGRT using a new digital accelerator equipped with onboard imaging system.

    Science.gov (United States)

    Wang, Lei; Kielar, Kayla N; Mok, Ed; Hsu, Annie; Dieterich, Sonja; Xing, Lei

    2012-02-07

    The Varian's new digital linear accelerator (LINAC), TrueBeam STx, is equipped with a high dose rate flattening filter free (FFF) mode (6 MV and 10 MV), a high definition multileaf collimator (2.5 mm leaf width), as well as onboard imaging capabilities. A series of end-to-end phantom tests were performed, TrueBeam-based image guided radiation therapy (IGRT), to determine the geometric accuracy of the image-guided setup and dose delivery process for all beam modalities delivered using intensity modulated radiation therapy (IMRT) and RapidArc. In these tests, an anthropomorphic phantom with a Ball Cube II insert and the analysis software (FilmQA (3cognition)) were used to evaluate the accuracy of TrueBeam image-guided setup and dose delivery. Laser cut EBT2 films with 0.15 mm accuracy were embedded into the phantom. The phantom with the film inserted was first scanned with a GE Discovery-ST CT scanner, and the images were then imported to the planning system. Plans with steep dose fall off surrounding hypothetical targets of different sizes were created using RapidArc and IMRT with FFF and WFF (with flattening filter) beams. Four RapidArc plans (6 MV and 10 MV FFF) and five IMRT plans (6 MV and 10 MV FFF; 6 MV, 10 MV and 15 MV WFF) were studied. The RapidArc plans with 6 MV FFF were planned with target diameters of 1 cm (0.52 cc), 2 cm (4.2 cc) and 3 cm (14.1 cc), and all other plans with a target diameter of 3 cm. Both onboard planar and volumetric imaging procedures were used for phantom setup and target localization. The IMRT and RapidArc plans were then delivered, and the film measurements were compared with the original treatment plans using a gamma criteria of 3%/1 mm and 3%/2 mm. The shifts required in order to align the film measured dose with the calculated dose distributions was attributed to be the targeting error. Targeting accuracy of image-guided treatment using TrueBeam was found to be within 1 mm. For irradiation of the 3 cm target, the gammas (3%, 1

  7. Healing of esophageal anastomoses performed with the biofragmentable anastomosis ring versus the end-to-end anastomosis stapler: comparative experimental study in dogs.

    Science.gov (United States)

    Kovács, Tibor; Köves, István; Orosz, Zsolt; Németh, Tibor; Pandi, Erzsébet; Kralovanszky, Judit

    2003-04-01

    The biofragmentable anastomosis ring (BAR) has been used successfully for anastomoses from the stomach to the upper rectum. The healing of intrathoracic esophageal anastomoses performed with the BAR or an end-to-end anastomosis (EEA) stapler on an experimental model was compared. Parameters of tissue repair were evaluated: macroscopic examination, bursting strength (BS), collagen (hydroxyproline, or HP), histology (H&E and Picrosirius red staining for collagen). A series of 48 mongrel dogs were randomly separated into two groups (30 BAR, 18 stapler) and subgroups according to the time of autopsy (days 4, 7, 14, 28). Mortality was 13.3% (4 BAR cases) with two deaths not related to surgery (excluded). There were four leaks in the BAR group (14.3%) and no leaks or deaths but two strictures in the stapler group. BS was significantly higher in the BAR group during the first week, and values were almost equal from the second week with both methods. The HP rate was significantly reduced on days 4 and 7 in both groups compared to the reference values; the values were close to reference values from the second week (lower in the BAR group). Stapled anastomoses caused less pronounced inflammation and were associated with an earlier start of regeneration, but the difference was not significant compared to that in the BAR group. Accumulation of new collagen (green polarization) started on day 7 in both groups, but maturation (orange-red polarization) was significantly more advanced in the BAR group after the second week. A strong linear correlation between the BS and HP rate was found with both methods. There was no significant difference in the complication rate or healing of intrathoracic BAR and stapled anastomoses. The BAR method is simple, quick, and safe; and it seems to be a feasible procedure for creating intrathoracic esophageal anastomoses in dogs.

  8. End-to-end process of hollow spacecraft structures with high frequency and low mass obtained with in-house structural optimization tool and additive manufacturing

    Directory of Open Access Journals (Sweden)

    Alexandru-Mihai CISMILIANU

    2017-09-01

    Full Text Available In the space sector the most decisive elements are: mass reduction, cost saving and minimum lead time; here, structural optimization and additive layer manufacturing (ALM fit best. The design must be driven by stiffness, because an important requirement for spacecraft (S/C structures is to reduce the dynamic coupling between the S/C and the launch vehicle. The objective is to create an end-to-end process, from the input given by the customer to the manufacturing of an aluminum part as light as possible but at the same time considerably stiffer while taking the full advantage of the design flexibility given by ALM. To design and optimize the parts, a specialized in-house tool was used, guaranteeing a load-sufficient material distribution. Using topological optimization, the iterations between the design and the stress departments were diminished, thus greatly reducing the lead time. In order to improve and lighten the obtained structure a design with internal cavities and hollow beams was considered. This implied developing of a procedure for powder evacuation through iterations with the manufacturer while optimizing the design for ALM. The resulted part can be then manufactured via ALM with no need of further design adjustments. To achieve a high-quality part with maximum efficiency, it is essential to have a loop between the design team and the manufacturer. Topological optimization and ALM work hand in hand if used properly. The team achieved a more efficient structure using topology optimization and ALM, than using conventional design and manufacturing methods.

  9. Automated Detection of Clinically Significant Prostate Cancer in mp-MRI Images Based on an End-to-End Deep Neural Network.

    Science.gov (United States)

    Wang, Zhiwei; Liu, Chaoyue; Cheng, Danpeng; Wang, Liang; Yang, Xin; Cheng, Kwang-Ting

    2018-05-01

    Automated methods for detecting clinically significant (CS) prostate cancer (PCa) in multi-parameter magnetic resonance images (mp-MRI) are of high demand. Existing methods typically employ several separate steps, each of which is optimized individually without considering the error tolerance of other steps. As a result, they could either involve unnecessary computational cost or suffer from errors accumulated over steps. In this paper, we present an automated CS PCa detection system, where all steps are optimized jointly in an end-to-end trainable deep neural network. The proposed neural network consists of concatenated subnets: 1) a novel tissue deformation network (TDN) for automated prostate detection and multimodal registration and 2) a dual-path convolutional neural network (CNN) for CS PCa detection. Three types of loss functions, i.e., classification loss, inconsistency loss, and overlap loss, are employed for optimizing all parameters of the proposed TDN and CNN. In the training phase, the two nets mutually affect each other and effectively guide registration and extraction of representative CS PCa-relevant features to achieve results with sufficient accuracy. The entire network is trained in a weakly supervised manner by providing only image-level annotations (i.e., presence/absence of PCa) without exact priors of lesions' locations. Compared with most existing systems which require supervised labels, e.g., manual delineation of PCa lesions, it is much more convenient for clinical usage. Comprehensive evaluation based on fivefold cross validation using 360 patient data demonstrates that our system achieves a high accuracy for CS PCa detection, i.e., a sensitivity of 0.6374 and 0.8978 at 0.1 and 1 false positives per normal/benign patient.

  10. Combined fishing and climate forcing in the southern Benguela upwelling ecosystem: an end-to-end modelling approach reveals dampened effects.

    Directory of Open Access Journals (Sweden)

    Morgane Travers-Trolet

    Full Text Available The effects of climate and fishing on marine ecosystems have usually been studied separately, but their interactions make ecosystem dynamics difficult to understand and predict. Of particular interest to management, the potential synergism or antagonism between fishing pressure and climate forcing is analysed in this paper, using an end-to-end ecosystem model of the southern Benguela ecosystem, built from coupling hydrodynamic, biogeochemical and multispecies fish models (ROMS-N2P2Z2D2-OSMOSE. Scenarios of different intensities of upwelling-favourable wind stress combined with scenarios of fishing top-predator fish were tested. Analyses of isolated drivers show that the bottom-up effect of the climate forcing propagates up the food chain whereas the top-down effect of fishing cascades down to zooplankton in unfavourable environmental conditions but dampens before it reaches phytoplankton. When considering both climate and fishing drivers together, it appears that top-down control dominates the link between top-predator fish and forage fish, whereas interactions between the lower trophic levels are dominated by bottom-up control. The forage fish functional group appears to be a central component of this ecosystem, being the meeting point of two opposite trophic controls. The set of combined scenarios shows that fishing pressure and upwelling-favourable wind stress have mostly dampened effects on fish populations, compared to predictions from the separate effects of the stressors. Dampened effects result in biomass accumulation at the top predator fish level but a depletion of biomass at the forage fish level. This should draw our attention to the evolution of this functional group, which appears as both structurally important in the trophic functioning of the ecosystem, and very sensitive to climate and fishing pressures. In particular, diagnoses considering fishing pressure only might be more optimistic than those that consider combined effects

  11. A novel PON based UMTS broadband wireless access network architecture with an algorithm to guarantee end to end QoS

    Science.gov (United States)

    Sana, Ajaz; Hussain, Shahab; Ali, Mohammed A.; Ahmed, Samir

    2007-09-01

    In this paper we proposes a novel Passive Optical Network (PON) based broadband wireless access network architecture to provide multimedia services (video telephony, video streaming, mobile TV, mobile emails etc) to mobile users. In the conventional wireless access networks, the base stations (Node B) and Radio Network Controllers (RNC) are connected by point to point T1/E1 lines (Iub interface). The T1/E1 lines are expensive and add up to operating costs. Also the resources (transceivers and T1/E1) are designed for peak hours traffic, so most of the time the dedicated resources are idle and wasted. Further more the T1/E1 lines are not capable of supporting bandwidth (BW) required by next generation wireless multimedia services proposed by High Speed Packet Access (HSPA, Rel.5) for Universal Mobile Telecommunications System (UMTS) and Evolution Data only (EV-DO) for Code Division Multiple Access 2000 (CDMA2000). The proposed PON based back haul can provide Giga bit data rates and Iub interface can be dynamically shared by Node Bs. The BW is dynamically allocated and the unused BW from lightly loaded Node Bs is assigned to heavily loaded Node Bs. We also propose a novel algorithm to provide end to end Quality of Service (QoS) (between RNC and user equipment).The algorithm provides QoS bounds in the wired domain as well as in wireless domain with compensation for wireless link errors. Because of the air interface there can be certain times when the user equipment (UE) is unable to communicate with Node B (usually referred to as link error). Since the link errors are bursty and location dependent. For a proposed approach, the scheduler at the Node B maps priorities and weights for QoS into wireless MAC. The compensations for errored links is provided by the swapping of services between the active users and the user data is divided into flows, with flows allowed to lag or lead. The algorithm guarantees (1)delay and throughput for error-free flows,(2)short term fairness

  12. SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Corradini, N; Leick, M; Bonetti, M; Negretti, L [Clinica Luganese, Radiotherapy Center, Lugano (Switzerland)

    2015-06-15

    Purpose: To determine the MVCT imaging uncertainty on the TomoHDA system for intracranial radiosurgery treatments. To determine the end-to-end (E2E) overall accuracy of the TomoHDA system for intracranial radiosurgery. Methods: A pig head was obtained from the butcher, cut coronally through the brain, and preserved in formaldehyde. The base of the head was fixed to a positioning plate allowing precise movement, i.e. translation and rotation, in all 6 axes. A repeatability test was performed on the pig head to determine uncertainty in the image bone registration algorithm. Furthermore, the test studied images with MVCT slice thicknesses of 1 and 3 mm in unison with differing scan lengths. A sensitivity test was performed to determine the registration algorithm’s ability to find the absolute position of known translations/rotations of the pig head. The algorithm’s ability to determine absolute position was compared against that of manual operators, i.e. a radiation therapist and radiation oncologist. Finally, E2E tests for intracranial radiosurgery were performed by measuring the delivered dose distributions within the pig head using Gafchromic films. Results: The repeatability test uncertainty was lowest for the MVCTs of 1-mm slice thickness, which measured less than 0.10 mm and 0.12 deg for all axes. For the sensitivity tests, the bone registration algorithm performed better than human eyes and a maximum difference of 0.3 mm and 0.4 deg was observed for the axes. E2E test results in absolute position difference measured 0.03 ± 0.21 mm in x-axis and 0.28 ± 0.18 mm in y-axis. A maximum difference of 0.32 and 0.66 mm was observed in x and y, respectively. The average peak dose difference between measured and calculated dose was 2.7 cGy or 0.4%. Conclusion: Our tests using a pig head phantom estimate the TomoHDA system to have a submillimeter overall accuracy for intracranial radiosurgery.

  13. SU-E-J-25: End-To-End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery

    International Nuclear Information System (INIS)

    Corradini, N; Leick, M; Bonetti, M; Negretti, L

    2015-01-01

    Purpose: To determine the MVCT imaging uncertainty on the TomoHDA system for intracranial radiosurgery treatments. To determine the end-to-end (E2E) overall accuracy of the TomoHDA system for intracranial radiosurgery. Methods: A pig head was obtained from the butcher, cut coronally through the brain, and preserved in formaldehyde. The base of the head was fixed to a positioning plate allowing precise movement, i.e. translation and rotation, in all 6 axes. A repeatability test was performed on the pig head to determine uncertainty in the image bone registration algorithm. Furthermore, the test studied images with MVCT slice thicknesses of 1 and 3 mm in unison with differing scan lengths. A sensitivity test was performed to determine the registration algorithm’s ability to find the absolute position of known translations/rotations of the pig head. The algorithm’s ability to determine absolute position was compared against that of manual operators, i.e. a radiation therapist and radiation oncologist. Finally, E2E tests for intracranial radiosurgery were performed by measuring the delivered dose distributions within the pig head using Gafchromic films. Results: The repeatability test uncertainty was lowest for the MVCTs of 1-mm slice thickness, which measured less than 0.10 mm and 0.12 deg for all axes. For the sensitivity tests, the bone registration algorithm performed better than human eyes and a maximum difference of 0.3 mm and 0.4 deg was observed for the axes. E2E test results in absolute position difference measured 0.03 ± 0.21 mm in x-axis and 0.28 ± 0.18 mm in y-axis. A maximum difference of 0.32 and 0.66 mm was observed in x and y, respectively. The average peak dose difference between measured and calculated dose was 2.7 cGy or 0.4%. Conclusion: Our tests using a pig head phantom estimate the TomoHDA system to have a submillimeter overall accuracy for intracranial radiosurgery

  14. Greenhouse gas profiling by infrared-laser and microwave occultation: retrieval algorithm and demonstration results from end-to-end simulations

    Directory of Open Access Journals (Sweden)

    V. Proschek

    2011-10-01

    Full Text Available Measuring greenhouse gas (GHG profiles with global coverage and high accuracy and vertical resolution in the upper troposphere and lower stratosphere (UTLS is key for improved monitoring of GHG concentrations in the free atmosphere. In this respect a new satellite mission concept adding an infrared-laser part to the already well studied microwave occultation technique exploits the joint propagation of infrared-laser and microwave signals between Low Earth Orbit (LEO satellites. This synergetic combination, referred to as LEO-LEO microwave and infrared-laser occultation (LMIO method, enables to retrieve thermodynamic profiles (pressure, temperature, humidity and accurate altitude levels from the microwave signals and GHG profiles from the simultaneously measured infrared-laser signals. However, due to the novelty of the LMIO method, a retrieval algorithm for GHG profiling is not yet available. Here we introduce such an algorithm for retrieving GHGs from LEO-LEO infrared-laser occultation (LIO data, applied as a second step after retrieving thermodynamic profiles from LEO-LEO microwave occultation (LMO data. We thoroughly describe the LIO retrieval algorithm and unveil the synergy with the LMO-retrieved pressure, temperature, and altitude information. We furthermore demonstrate the effective independence of the GHG retrieval results from background (a priori information in discussing demonstration results from LMIO end-to-end simulations for a representative set of GHG profiles, including carbon dioxide (CO2, water vapor (H2O, methane (CH4, and ozone (O3. The GHGs except for ozone are well retrieved throughout the UTLS, while ozone is well retrieved from about 10 km to 15 km upwards, since the ozone layer resides in the lower stratosphere. The GHG retrieval errors are generally smaller than 1% to 3% r.m.s., at a vertical resolution of about 1 km. The retrieved profiles also appear unbiased, which points

  15. SU-E-T-19: A New End-To-End Test Method for ExacTrac for Radiation and Plan Isocenter Congruence

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S; Nguyen, N; Liu, F; Huang, Y [Rhode Island Hospital / Warren Alpert Medical, Providence, RI (United States); Sio, T [Mayo Clinic, Rochester, MN (United States); Jung, J [East Carolina University, Greenville, North Carolina (United States); Pyakuryal, A [UniversityIllinois at Chicago, Chicago, IL (United States); Jang, S [Princeton Radiation Oncology Ctr., Jamesburg, NJ (United States)

    2014-06-01

    Purpose: To combine and integrate quality assurance (QA) of target localization and radiation isocenter End to End (E2E) test of BrainLAB ExacTrac system, a new QA approach was devised using anthropomorphic head and neck phantom. This test insures the target localization as well as radiation isocenter congruence which is one step ahead the current ExacTrac QA procedures. Methods: The head and neck phantom typically used for CyberKnife E2E test was irradiated to the sphere target that was visible in CT-sim images. The CT-sim was performed using 1 mm thickness slice with helical scanning technique. The size of the sphere was 3-cm diameter and contoured as a target volume using iPlan V.4.5.2. A conformal arc plan was generated using MLC-based with 7 fields, and five of them were include couch rotations. The prescription dose was 5 Gy and 95% coverage to the target volume. For the irradiation, two Gafchromic films were perpendicularly inserted into the cube that hold sphere inside. The linac used for the irradiation was TrueBeam STx equipped with HD120 MLC. In order to use ExacTrac, infra-red head–array was used to correlate orthogonal X-ray images. Results: Using orthogonal X-rays of ExacTrac the phantom was positioned. For each field, phantom was check again with X-rays and re-positioned if necessary. After each setup using ExacTrac, the target was irradiated. The films were analyzed to determine the deviation of the radiation isocenter in all three dimensions: superior-inferior, left-right and anterior-posterior. The total combining error was found to be 0.76 mm ± 0.05 mm which was within sub-millimeter accuracy. Conclusion: Until now, E2E test for ExacTrac was separately implemented to test image localization and radiation isocenter. This new method can be used for periodic QA procedures.

  16. RTEMP: Exploring an end-to-end, agnostic platform for multidisciplinary real-time analytics in the space physics community and beyond

    Science.gov (United States)

    Chaddock, D.; Donovan, E.; Spanswick, E.; Jackel, B. J.

    2014-12-01

    Large-scale, real-time, sensor-driven analytics are a highly effective set of tools in many research environments; however, the barrier to entry is expensive and the learning curve is steep. These systems need to operate efficiently from end to end, with the key aspects being data transmission, acquisition, management and organization, and retrieval. When building a generic multidisciplinary platform, acquisition and data management needs to be designed with scalability and flexibility as the primary focus. Additionally, in order to leverage current sensor web technologies, the integration of common sensor data standards (ie. SensorML and SWE Services) should be supported. Perhaps most important, researchers should be able to get started and integrate the platform into their set of research tools as easily and quickly as possible. The largest issue with current platforms is that the sensor data must be formed and described using the previously mentioned standards. As useful as these standards are for organizing data, they are cumbersome to adopt, often restrictive, and are required to be geospatially-driven. Our solution, RTEMP (Real-time Environment Monitoring Platform), is a real-time analytics platform with over ten years and an estimated two million dollars of investment. It has been developed for our continuously expanding requirements of operating and building remote sensors and supporting equipment for space physics research. A key benefit of our approach is RTEMP's ability to manage agnostic data. This allows data that flows through the system to be structured in any way that best addresses the needs of the sensor operators and data users, enabling extensive flexibility and streamlined development and research. Here we begin with an overview of RTEMP and how it is structured. Additionally, we will showcase the ways that we are using RTEMP and how it is being adopted by researchers in an increasingly broad range of other research fields. We will lay out a

  17. WE-DE-BRA-11: A Study of Motion Tracking Accuracy of Robotic Radiosurgery Using a Novel CCD Camera Based End-To-End Test System

    Energy Technology Data Exchange (ETDEWEB)

    Wang, L; M Yang, Y [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA (United States); Nelson, B [Logos Systems Intl, Scotts Valley, CA (United States)

    2016-06-15

    Purpose: A novel end-to-end test system using a CCD camera and a scintillator based phantom (XRV-124, Logos Systems Int’l) capable of measuring the beam-by-beam delivery accuracy of Robotic Radiosurgery (CyberKnife) was developed and reported in our previous work. This work investigates its application in assessing the motion tracking (Synchrony) accuracy for CyberKnife. Methods: A QA plan with Anterior and Lateral beams (with 4 different collimator sizes) was created (Multiplan v5.3) for the XRV-124 phantom. The phantom was placed on a motion platform (superior and inferior movement), and the plans were delivered on the CyberKnife M6 system using four motion patterns: static, Sine- wave, Sine with 15° phase shift, and a patient breathing pattern composed of 2cm maximum motion with 4 second breathing cycle. Under integral recording mode, the time-averaged beam vectors (X, Y, Z) were measured by the phantom and compared with static delivery. In dynamic recording mode, the beam spots were recorded at a rate of 10 frames/second. The beam vector deviation from average position was evaluated against the various breathing patterns. Results: The average beam position of the six deliveries with no motion and three deliveries with Synchrony tracking on ideal motion (sinewave without phase shift) all agree within −0.03±0.00 mm, 0.10±0.04, and 0.04±0.03 in the X, Y, and X directions. Radiation beam width (FWHM) variations are within ±0.03 mm. Dynamic video record showed submillimeter tracking stability for both regular and irregular breathing pattern; however the tracking error up to 3.5 mm was observed when a 15 degree phase shift was introduced. Conclusion: The XRV-124 system is able to provide 3D and 4D targeting accuracy for CyberKnife delivery with Synchrony. The experimental results showed sub-millimeter delivery in phantom with excellent correlation in target to breathing motion. The accuracy was degraded when irregular motion and phase shift was introduced.

  18. Status of the ELIMED multidisciplinary and medical beam-line at ELI-Beamlines

    International Nuclear Information System (INIS)

    Romano, F; Cirrone, G A P; Cuttone, G; Schillaci, F; Scuderi, V; Amico, A; Candiano, G; Larosa, G; Leanza, R; Manna, R; Marchese, V; Milluzzo, G; Petringa, G; Pipek, J; Giordanengo, S; Guarachi, L F; Marchetto, F; Sacchi, R; Korn, G; Margarone, D

    2017-01-01

    Nowadays, one of the biggest challenges consists in using high intensity laser-target interaction to generate high-energy ions for medical purposes, eventually replacing the old paradigm of acceleration characterized by huge and complex machines. In order to investigate the feasibility of using laser-driven ion beams for multidisciplinary application, a dedicated beam transport line will be installed at the ELI-Beamlines facility in Prague (CZ), as a part of the User-oriented ELIMAIA beam-line dedicated to ion acceleration and their potential applications. The beam-line section dedicated to transport and dosimetric endpoints is called ELIMED (ELI-Beamlines MEDical and multidisciplinary applications) and will be developed by the INFN-LNS. (paper)

  19. Distributed control of protein crystallography beamline 5.0 using CORBA

    International Nuclear Information System (INIS)

    Timossi, Chris

    1999-01-01

    The Protein Crystallography Beamline at Berkeley Lab's Advanced Light Source is a facility that is being used to solve the structure of proteins. The software that is being used to control this beamline uses Java for user interface applications which communicate via CORBA with workstations that control the beamline hardware. We describe the software architecture for the beamline and our experiences after two years of operation

  20. BNL ATF II beamlines design

    Energy Technology Data Exchange (ETDEWEB)

    Fedurin, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Jing, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Stratakis, D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Swinson, C. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-05-03

    The Brookhaven National Laboratory. Accelerator Test Facility (BNL ATF) is currently undergoing a major upgrade (ATF-II). Together with a new location and much improved facilities, the ATF will see an upgrade in its major capabilities: electron beam energy and quality and CO2 laser power. The electron beam energy will be increased in stages, first to 100-150 MeV followed by a further increase to 500 MeV. Combined with the planned increase in CO2 laser power (from 1-100 TW), the ATF-II will be a powerful tool for Advanced Accelerator research. A high-brightness electron beam, produced by a photocathode gun, will be accelerated and optionally delivered to multiple beamlines. Besides the energy range (up to a possible 500 MeV in the final stage) the electron beam can be tailored to each experiment with options such as: small transverse beam size (<10 um), short bunch length (<100 fsec) and, combined short and small bunch options. This report gives a detailed overview of the ATFII capabilities and beamlines configuration.

  1. A Vehicle Management End-to-End Testing and Analysis Platform for Validation of Mission and Fault Management Algorithms to Reduce Risk for NASA's Space Launch System

    Science.gov (United States)

    Trevino, Luis; Johnson, Stephen B.; Patterson, Jonathan; Teare, David

    2015-01-01

    The development of the Space Launch System (SLS) launch vehicle requires cross discipline teams with extensive knowledge of launch vehicle subsystems, information theory, and autonomous algorithms dealing with all operations from pre-launch through on orbit operations. The characteristics of these systems must be matched with the autonomous algorithm monitoring and mitigation capabilities for accurate control and response to abnormal conditions throughout all vehicle mission flight phases, including precipitating safing actions and crew aborts. This presents a large complex systems engineering challenge being addressed in part by focusing on the specific subsystems handling of off-nominal mission and fault tolerance. Using traditional model based system and software engineering design principles from the Unified Modeling Language (UML), the Mission and Fault Management (M&FM) algorithms are crafted and vetted in specialized Integrated Development Teams composed of multiple development disciplines. NASA also has formed an M&FM team for addressing fault management early in the development lifecycle. This team has developed a dedicated Vehicle Management End-to-End Testbed (VMET) that integrates specific M&FM algorithms, specialized nominal and off-nominal test cases, and vendor-supplied physics-based launch vehicle subsystem models. The flexibility of VMET enables thorough testing of the M&FM algorithms by providing configurable suites of both nominal and off-nominal test cases to validate the algorithms utilizing actual subsystem models. The intent is to validate the algorithms and substantiate them with performance baselines for each of the vehicle subsystems in an independent platform exterior to flight software test processes. In any software development process there is inherent risk in the interpretation and implementation of concepts into software through requirements and test processes. Risk reduction is addressed by working with other organizations such as S

  2. Circular dichroism beamline B23 at the Diamond Light Source.

    Science.gov (United States)

    Hussain, Rohanah; Jávorfi, Tamás; Siligardi, Giuliano

    2012-01-01

    Synchrotron radiation circular dichroism (SRCD) is a well established technique in structural biology. The first UV-VIS beamline, dedicated to circular dichroism, at Diamond Light Source Ltd, a third-generation synchrotron facility in south Oxfordshire, UK, has recently become operational and it is now available for the user community. Herein the main characteristics of the B23 SRCD beamline, the ancillary facilities available for users, and some of the recent advances achieved are summarized.

  3. A Vehicle Management End-to-End Testing and Analysis Platform for Validation of Mission and Fault Management Algorithms to Reduce Risk for NASA's Space Launch System

    Science.gov (United States)

    Trevino, Luis; Patterson, Jonathan; Teare, David; Johnson, Stephen

    2015-01-01

    integrates specific M&FM algorithms, specialized nominal and off-nominal test cases, and vendor-supplied physics-based launch vehicle subsystem models. Additionally, the team has developed processes for implementing and validating these algorithms for concept validation and risk reduction for the SLS program. The flexibility of the Vehicle Management End-to-end Testbed (VMET) enables thorough testing of the M&FM algorithms by providing configurable suites of both nominal and off-nominal test cases to validate the developed algorithms utilizing actual subsystem models such as MPS. The intent of VMET is to validate the M&FM algorithms and substantiate them with performance baselines for each of the target vehicle subsystems in an independent platform exterior to the flight software development infrastructure and its related testing entities. In any software development process there is inherent risk in the interpretation and implementation of concepts into software through requirements and test cases into flight software compounded with potential human errors throughout the development lifecycle. Risk reduction is addressed by the M&FM analysis group working with other organizations such as S&MA, Structures and Environments, GNC, Orion, the Crew Office, Flight Operations, and Ground Operations by assessing performance of the M&FM algorithms in terms of their ability to reduce Loss of Mission and Loss of Crew probabilities. In addition, through state machine and diagnostic modeling, analysis efforts investigate a broader suite of failure effects and associated detection and responses that can be tested in VMET to ensure that failures can be detected, and confirm that responses do not create additional risks or cause undesired states through interactive dynamic effects with other algorithms and systems. VMET further contributes to risk reduction by prototyping and exercising the M&FM algorithms early in their implementation and without any inherent hindrances such as meeting FSW

  4. A Vehicle Management End-to-End Testing and Analysis Platform for Validation of Mission and Fault Management Algorithms to Reduce Risk for NASAs Space Launch System

    Science.gov (United States)

    Trevino, Luis; Johnson, Stephen B.; Patterson, Jonathan; Teare, David

    2015-01-01

    The engineering development of the National Aeronautics and Space Administration's (NASA) new Space Launch System (SLS) requires cross discipline teams with extensive knowledge of launch vehicle subsystems, information theory, and autonomous algorithms dealing with all operations from pre-launch through on orbit operations. The nominal and off-nominal characteristics of SLS's elements and subsystems must be understood and matched with the autonomous algorithm monitoring and mitigation capabilities for accurate control and response to abnormal conditions throughout all vehicle mission flight phases, including precipitating safing actions and crew aborts. This presents a large and complex systems engineering challenge, which is being addressed in part by focusing on the specific subsystems involved in the handling of off-nominal mission and fault tolerance with response management. Using traditional model-based system and software engineering design principles from the Unified Modeling Language (UML) and Systems Modeling Language (SysML), the Mission and Fault Management (M&FM) algorithms for the vehicle are crafted and vetted in Integrated Development Teams (IDTs) composed of multiple development disciplines such as Systems Engineering (SE), Flight Software (FSW), Safety and Mission Assurance (S&MA) and the major subsystems and vehicle elements such as Main Propulsion Systems (MPS), boosters, avionics, Guidance, Navigation, and Control (GNC), Thrust Vector Control (TVC), and liquid engines. These model-based algorithms and their development lifecycle from inception through FSW certification are an important focus of SLS's development effort to further ensure reliable detection and response to off-nominal vehicle states during all phases of vehicle operation from pre-launch through end of flight. To test and validate these M&FM algorithms a dedicated test-bed was developed for full Vehicle Management End-to-End Testing (VMET). For addressing fault management (FM

  5. Macromolecular crystallography beamline X25 at the NSLS

    Energy Technology Data Exchange (ETDEWEB)

    Héroux, Annie; Allaire, Marc; Buono, Richard; Cowan, Matthew L.; Dvorak, Joseph; Flaks, Leon; LaMarra, Steven; Myers, Stuart F.; Orville, Allen M.; Robinson, Howard H.; Roessler, Christian G.; Schneider, Dieter K.; Shea-McCarthy, Grace; Skinner, John M.; Skinner, Michael; Soares, Alexei S.; Sweet, Robert M.; Berman, Lonny E., E-mail: berman@bnl.gov [Brookhaven National Laboratory, PO Box 5000, Upton, NY 11973-5000 (United States)

    2014-04-08

    A description of the upgraded beamline X25 at the NSLS, operated by the PXRR and the Photon Sciences Directorate serving the Macromolecular Crystallography community, is presented. Beamline X25 at the NSLS is one of the five beamlines dedicated to macromolecular crystallography operated by the Brookhaven National Laboratory Macromolecular Crystallography Research Resource group. This mini-gap insertion-device beamline has seen constant upgrades for the last seven years in order to achieve mini-beam capability down to 20 µm × 20 µm. All major components beginning with the radiation source, and continuing along the beamline and its experimental hutch, have changed to produce a state-of-the-art facility for the scientific community.

  6. Macromolecular crystallography beamline X25 at the NSLS

    International Nuclear Information System (INIS)

    Héroux, Annie; Allaire, Marc; Buono, Richard; Cowan, Matthew L.; Dvorak, Joseph; Flaks, Leon; LaMarra, Steven; Myers, Stuart F.; Orville, Allen M.; Robinson, Howard H.; Roessler, Christian G.; Schneider, Dieter K.; Shea-McCarthy, Grace; Skinner, John M.; Skinner, Michael; Soares, Alexei S.; Sweet, Robert M.; Berman, Lonny E.

    2014-01-01

    A description of the upgraded beamline X25 at the NSLS, operated by the PXRR and the Photon Sciences Directorate serving the Macromolecular Crystallography community, is presented. Beamline X25 at the NSLS is one of the five beamlines dedicated to macromolecular crystallography operated by the Brookhaven National Laboratory Macromolecular Crystallography Research Resource group. This mini-gap insertion-device beamline has seen constant upgrades for the last seven years in order to achieve mini-beam capability down to 20 µm × 20 µm. All major components beginning with the radiation source, and continuing along the beamline and its experimental hutch, have changed to produce a state-of-the-art facility for the scientific community

  7. Demonstration of the First Real-Time End-to-End 40-Gb/s PAM-4 for Next-Generation Access Applications using 10-Gb/s Transmitter

    DEFF Research Database (Denmark)

    Wei, J. L.; Eiselt, Nicklas; Griesser, Helmut

    2016-01-01

    We demonstrate the first known experiment of a real-time end-to-end 40-Gb/s PAM-4 system for next-generation access applications using 10-Gb/s class transmitters only. Based on the measurement of a real-time 40-Gb/s PAM system, low-cost upstream and downstream link power budgets are estimated. Up...

  8. NPP Information Model as an Innovative Approach to End-to-End Lifecycle Management of the NPP and Nuclear Knowledge Management Proven in Russia

    International Nuclear Information System (INIS)

    Tikhonovsky, V.; Kanischev, A.; Kononov, V.; Salnikov, N.; Shkarin, A.; Dorobin, D.

    2016-01-01

    Full text: Managing engineering data for an industrial facility, including integration and maintenance of all engineering and technical data, ensuring fast and convenient access to that information and its analysis, proves to be necessary in order to perform the following tasks: 1) to increase economic efficiency of the plant during its lifecycle, including the decommissioning stage; 2) to ensure strict adherence to industrial safety requirements, radiation safety requirements (in case of nuclear facilities) and environmental safety requirements during operation (including refurbishment and restoration projects) and decommissioning. While performing tasks 1) and 2), one faces a range of challenges: 1. A huge amount of information describing the plant configuration. 2. Complexity of engineering procedures, step-by-step commissioning and significant geographical distribution of industrial infrastructure. 3. High importance of plant refurbishment projects. 4. The need to ensure comprehensive knowledge transfer between different generations of operational personnel and, which is especially important for the nuclear energy industry, between the commissioning personnel generations. NPP information model is an innovative method of NPP knowledge management throughout the whole plant lifecycle. It is an integrated database with all NPP technical engineering information (design, construction, operation, diagnosing, maintenance, refurbishment). (author

  9. Beamline instrumentation and experiment automation for the Rossendorf Beamline at ESRF/Grenoble (F)

    International Nuclear Information System (INIS)

    Oehme, W.; Dienel, S.; Proehl, D.

    2000-03-01

    The Rossendorf research center finished the work (from 1996 - 1998) for building its own beamline for experiments with synchrotron radiation at the ESRF (European Synchrotron Radiation Facility) at Grenoble/France. The beamline has two measuring systems for alternative use for experiments investigating radioactive samples by means of X-ray absorption spectrometry, and materials structures by means of X-ray diffraction analyses. The report in hand focuses on work performed required for the control equipment for optical systems and performance of the measuring systems with respect to electronics, calculation methods, and software. Hardware components of importance to system instrumentation are explained, as well as the basic computing tasks and general software principles, and are illustrated with some examples. The general setting of the beamline is represented in a tabulated overview. The literature list serves as a guideline for detailed documentation. (orig./CB) [de

  10. Secure network for beamline control

    International Nuclear Information System (INIS)

    Ohata, T.; Fukui, T.; Ishii, M.; Furukawa, Y.; Nakatani, T.; Matsushita, T.; Takeuchi, M.; Tanaka, R.; Ishikawa, T.

    2001-01-01

    In SPring-8, beamline control system is constructed with a highly available distributed network system. The socket based communication protocol is used for the beamline control mainly. Beamline users can control the equipment by sending simple control commands to a server process, which is running on a beamline-managing computer (Ohata et al., SPring-8 beamline control system, ICALEPCS'99, Trieste, Italy, 1999). At the beginning the network was based on the shared topology at all beamlines. Consequently, it has a risk for misapplication of the user's program to access different machines on the network system cross over beamlines. It is serious problem for the SPring-8 beamline control system, because all beamlines controlled with unified software interfaces. We introduced the switching technology and the firewalls to support network access control. Also the virtual networking (VLAN: IEEE 802.1Q) and the gigabit Ethernet technology (IEEE 802.3ab) are introduced. Thus the network security and the reliability are guaranteed at the higher level in SPring-8 beamline

  11. How good can our beamlines be?

    Energy Technology Data Exchange (ETDEWEB)

    Liebschner, Dorothee; Dauter, Miroslawa; Rosenbaum, Gerold, E-mail: rosenbaum@anl.gov; Dauter, Zbigniew, E-mail: rosenbaum@anl.gov [Argonne National Laboratory, Argonne, IL 60439 (United States)

    2012-10-01

    A repetitive measurement of the same diffraction image allows to judge the performance of a data collection facility. The accuracy of X-ray diffraction data depends on the properties of the crystalline sample and on the performance of the data-collection facility (synchrotron beamline elements, goniostat, detector etc.). However, it is difficult to evaluate the level of performance of the experimental setup from the quality of data sets collected in rotation mode, as various crystal properties such as mosaicity, non-uniformity and radiation damage affect the measured intensities. A multiple-image experiment, in which several analogous diffraction frames are recorded consecutively at the same crystal orientation, allows minimization of the influence of the sample properties. A series of 100 diffraction images of a thaumatin crystal were measured on the SBC beamline 19BM at the APS (Argonne National Laboratory). The obtained data were analyzed in the context of the performance of the data-collection facility. An objective way to estimate the uncertainties of individual reflections was achieved by analyzing the behavior of reflection intensities in the series of analogous diffraction images. The multiple-image experiment is found to be a simple and adequate method to decompose the random errors from the systematic errors in the data, which helps in judging the performance of a data-collection facility. In particular, displaying the intensity as a function of the frame number allows evaluation of the stability of the beam, the beamline elements and the detector with minimal influence of the crystal properties. Such an experiment permits evaluation of the highest possible data quality potentially achievable at the particular beamline.

  12. Treatment of a partially thrombosed giant aneurysm of the vertebral artery by aneurysm trapping and direct vertebral artery-posterior inferior cerebellar artery end-to-end anastomosis: technical case report.

    Science.gov (United States)

    Benes, Ludwig; Kappus, Christoph; Sure, Ulrich; Bertalanffy, Helmut

    2006-07-01

    The purpose of this article is to focus for the first time on the operative management of a direct vertebral artery (VA)-posterior inferior cerebellar artery (PICA) end-to-end anastomosis in a partially thrombosed giant VA-PICA-complex aneurysm and to underline its usefulness as an additional treatment option. The operative technique of a direct VA-PICA end-to-end anatomosis is described in detail. The VA was entering the large aneurysm sack. Distally, the PICA originated from the aneurysm sack-VA-complex. The donor and recipient vessel were cut close to the aneurysm. Whereas the VA was cut in a straight manner, the PICA was cut at an oblique 45-degree angle to enlarge the vascular end diameter. Vessel ends were flushed with heparinized saline and sutured. The thrombotic material inside the aneurysm sack was removed and the distal VA clipped, leaving the anterior spinal artery and brainstem perforators free. The patient regained consciousness without additional morbidity. Magnetic resonance imaging scans revealed a completely decompressed brainstem without infarction. The postoperative angiograms demonstrated a good filling of the anastomosed PICA. Despite the caliber mistmatch of these two vessels the direct VA-PICA end-to-end anastomosis provides an accurate alternative in addition to other anastomoses and bypass techniques, when donor and recipient vessels are suitable and medullary perforators do not have to be disrupted.

  13. Discussions for the shielding materials of synchrotron radiation beamline hutches

    International Nuclear Information System (INIS)

    Asano, Y.

    2006-01-01

    Many synchrotron radiation facilities are now under operation such as E.S.R.F., APS, and S.P.ring-8. New facilities with intermediated stored electron energy are also under construction and designing such as D.I.A.M.O.N.D., S.O.L.E.I.L., and S.S.R.F.. At these third generation synchrotron radiation facilities, the beamline shielding as well as the bulk shield is very important for designing radiation safety because of intense and high energy synchrotron radiation beam. Some reasons employ lead shield wall for the synchrotron radiation beamlines. One is narrow space for the construction of many beamlines at the experimental hall, and the other is the necessary of many movable mechanisms at the beamlines, for examples. Some cases are required to shield high energy neutrons due to stored electron beam loss and photoneutrons due to gas Bremsstrahlung. Ordinary concrete and heavy concrete are coming up to shield material of synchrotron radiation beamline hutches. However, few discussions have been performed so far for the shielding materials of the hutches. In this presentation, therefore, we will discuss the characteristics of the shielding conditions including build up effect for the beamline hutches by using the ordinary concrete, heavy concrete, and lead for shielding materials with 3 GeV and 8 GeV class synchrotron radiation source. (author)

  14. National Renewable Energy Laboratory (NREL) Topic 2 Final Report: End-to-End Communication and Control System to Support Clean Energy Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Hudgins, Andrew P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Carrillo, Ismael M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jin, Xin [National Renewable Energy Lab. (NREL), Golden, CO (United States); Simmins, John [Electric Power Research Inst. (EPRI), Palo Alto, CA (United States)

    2018-02-21

    This document is the final report of a two-year development, test, and demonstration project, 'Cohesive Application of Standards- Based Connected Devices to Enable Clean Energy Technologies.' The project was part of the National Renewable Energy Laboratory's (NREL's) Integrated Network Testbed for Energy Grid Research and Technology (INTEGRATE) initiative hosted at Energy Systems Integration Facility (ESIF). This project demonstrated techniques to control distribution grid events using the coordination of traditional distribution grid devices and high-penetration renewable resources and demand response. Using standard communication protocols and semantic standards, the project examined the use cases of high/low distribution voltage, requests for volt-ampere-reactive (VAR) power support, and transactive energy strategies using Volttron. Open source software, written by EPRI to control distributed energy resources (DER) and demand response (DR), was used by an advanced distribution management system (ADMS) to abstract the resources reporting to a collection of capabilities rather than needing to know specific resource types. This architecture allows for scaling both horizontally and vertically. Several new technologies were developed and tested. Messages from the ADMS based on the common information model (CIM) were developed to control the DER and DR management systems. The OpenADR standard was used to help manage grid events by turning loads off and on. Volttron technology was used to simulate a homeowner choosing the price at which to enter the demand response market. Finally, the ADMS used newly developed algorithms to coordinate these resources with a capacitor bank and voltage regulator to respond to grid events.

  15. Design and Construction of a High-speed Network Connecting All the Protein Crystallography Beamlines at the Photon Factory

    International Nuclear Information System (INIS)

    Matsugaki, Naohiro; Yamada, Yusuke; Igarashi, Noriyuki; Wakatsuki, Soichi

    2007-01-01

    A private network, physically separated from the facility network, was designed and constructed which covered all the four protein crystallography beamlines at the Photon Factory (PF) and Structural Biology Research Center (SBRC). Connecting all the beamlines in the same network allows for simple authentication and a common working environment for a user who uses multiple beamlines. Giga-bit Ethernet wire-speed was achieved for the communication among the beamlines and SBRC buildings

  16. Simulation of beamline alignment operations

    International Nuclear Information System (INIS)

    Annese, C; Miller, M G.

    1999-01-01

    The CORBA-based Simulator was a Laboratory Directed Research and Development (LDRD) project that applied simulation techniques to explore critical questions about distributed control systems. The simulator project used a three-prong approach that studied object-oriented distribution tools, computer network modeling, and simulation of key control system scenarios. The National Ignition Facility's (NIF) optical alignment system was modeled to study control system operations. The alignment of NIF's 192 beamlines is a large complex operation involving more than 100 computer systems and 8000 mechanized devices. The alignment process is defined by a detailed set of procedures; however, many of the steps are deterministic. The alignment steps for a poorly aligned component are similar to that of a nearly aligned component; however, additional operations/iterations are required to complete the process. Thus, the same alignment operations will require variable amounts of time to perform depending on the current alignment condition as well as other factors. Simulation of the alignment process is necessary to understand beamline alignment time requirements and how shared resources such as the Output Sensor and Target Alignment Sensor effect alignment efficiency. The simulation has provided alignment time estimates and other results based on documented alignment procedures and alignment experience gained in the laboratory. Computer communication time, mechanical hardware actuation times, image processing algorithm execution times, etc. have been experimentally determined and incorporated into the model. Previous analysis of alignment operations utilized average implementation times for all alignment operations. Resource sharing becomes rather simple to model when only average values are used. The time required to actually implement the many individual alignment operations will be quite dynamic. The simulation model estimates the time to complete an operation using

  17. Construction of Bending Magnet Beamline at the APS for Environmental Studies

    International Nuclear Information System (INIS)

    Stern, E.A.

    1999-01-01

    The objective of this research was to design and construct a bending magnet beamline at the Advanced Photon Source. The beamline is to be optimized for x-ray absorption spectroscopy (XAS) studies with a major focus on environmental issues. The beamline will share the experimental facilities under development at the neighboring undulator-based insertion device beamline. It will utilize these facilities for XAS of both bulk and surface samples, with spatial and elemental imaging, on toxic and radioactive samples. It will help meet the rapidly growing need for the application of these techniques to environmental problems

  18. The monitoring system for macromolecular crystallography beamlines at BSRF

    International Nuclear Information System (INIS)

    Guo Xian; Chang Guangcai; Gan Quan; Shi Hong; Liu Peng; Sun Gongxing

    2012-01-01

    The monitoring system for macromolecular crystallography beamlines at BSRF (Beijing Synchrotron Radiation Facility) based on LabVIEW is introduced. In order to guarantee a safe, stable, and reliable running for the beamline devices, the system monitors the state of vacuum, cooling-water, optical components, beam, Liquid nitrogen in the beamlines in real time, detects faults and gives the alarm timely. System underlying uses the driver developed for the field devices for data acquisition, Data of collection is uploaded to the data-sharing platform makes it accessible via a network share. The upper system divides modules according to the actual function, and establishes the main interface of the monitoring system of beamline. To Facilitate data storage, management and inquiry, the system use LabSQL toolkit to achieve the interconnection with MySQL database which data of collection is sent to. (authors)

  19. 1993 CAT workshop on beamline optical designs

    International Nuclear Information System (INIS)

    1993-11-01

    An Advanced Photon Source (APS) Collaborative Access Team (CAT) Workshop on Beamline Optical Designs was held at Argonne National Laboratory on July 26--27, 1993. The goal of this workshop was to bring together experts from various synchrotron sources to provide status reports on crystal, reflecting, and polarizing optics as a baseline for discussions of issues facing optical designers for CAT beamlines at the APS. Speakers from the European Synchrotron Radiation Facility (ESRF), the University of Chicago, the National Synchrotron Light Source, and the University of Manchester (England) described single- and double-crystal monochromators, mirrors, glass capillaries, and polarizing optics. Following these presentations, the 90 participants divided into three working groups: Crystal Optics Design, Reflecting Optics, and Optics for Polarization Studies. This volume contains copies of the presentation materials from all speakers, summaries of the three working groups, and a ''catalog'' of various monochromator designs

  20. 1993 CAT workshop on beamline optical designs

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    An Advanced Photon Source (APS) Collaborative Access Team (CAT) Workshop on Beamline Optical Designs was held at Argonne National Laboratory on July 26--27, 1993. The goal of this workshop was to bring together experts from various synchrotron sources to provide status reports on crystal, reflecting, and polarizing optics as a baseline for discussions of issues facing optical designers for CAT beamlines at the APS. Speakers from the European Synchrotron Radiation Facility (ESRF), the University of Chicago, the National Synchrotron Light Source, and the University of Manchester (England) described single- and double-crystal monochromators, mirrors, glass capillaries, and polarizing optics. Following these presentations, the 90 participants divided into three working groups: Crystal Optics Design, Reflecting Optics, and Optics for Polarization Studies. This volume contains copies of the presentation materials from all speakers, summaries of the three working groups, and a ``catalog`` of various monochromator designs.

  1. SU-F-P-39: End-To-End Validation of a 6 MV High Dose Rate Photon Beam, Configured for Eclipse AAA Algorithm Using Golden Beam Data, for SBRT Treatments Using RapidArc

    Energy Technology Data Exchange (ETDEWEB)

    Ferreyra, M; Salinas Aranda, F; Dodat, D; Sansogne, R; Arbiser, S [Vidt Centro Medico, Ciudad Autonoma De Buenos Aires, Ciudad Autonoma de Buenos Aire (Argentina)

    2016-06-15

    Purpose: To use end-to-end testing to validate a 6 MV high dose rate photon beam, configured for Eclipse AAA algorithm using Golden Beam Data (GBD), for SBRT treatments using RapidArc. Methods: Beam data was configured for Varian Eclipse AAA algorithm using the GBD provided by the vendor. Transverse and diagonals dose profiles, PDDs and output factors down to a field size of 2×2 cm2 were measured on a Varian Trilogy Linac and compared with GBD library using 2% 2mm 1D gamma analysis. The MLC transmission factor and dosimetric leaf gap were determined to characterize the MLC in Eclipse. Mechanical and dosimetric tests were performed combining different gantry rotation speeds, dose rates and leaf speeds to evaluate the delivery system performance according to VMAT accuracy requirements. An end-to-end test was implemented planning several SBRT RapidArc treatments on a CIRS 002LFC IMRT Thorax Phantom. The CT scanner calibration curve was acquired and loaded in Eclipse. PTW 31013 ionization chamber was used with Keithley 35617EBS electrometer for absolute point dose measurements in water and lung equivalent inserts. TPS calculated planar dose distributions were compared to those measured using EPID and MapCheck, as an independent verification method. Results were evaluated with gamma criteria of 2% dose difference and 2mm DTA for 95% of points. Results: GBD set vs. measured data passed 2% 2mm 1D gamma analysis even for small fields. Machine performance tests show results are independent of machine delivery configuration, as expected. Absolute point dosimetry comparison resulted within 4% for the worst case scenario in lung. Over 97% of the points evaluated in dose distributions passed gamma index analysis. Conclusion: Eclipse AAA algorithm configuration of the 6 MV high dose rate photon beam using GBD proved efficient. End-to-end test dose calculation results indicate it can be used clinically for SBRT using RapidArc.

  2. SIP end to end performance metrics

    OpenAIRE

    Vozňák, Miroslav; Rozhon, Jan

    2012-01-01

    The paper deals with a SIP performance testing methodology. The main contribution to the field of performance testing of SIP infrastructure consists in the possibility to perform the standardized stress tests with the developed SIP TesterApp without a deeper knowledge in the area of SIP communication. The developed tool exploits several of open-source applications such as jQuery, Python, JSON and the cornerstone SIP generator SIPp, the result is highly modifiable and the ...

  3. End-to-end energy efficient communication

    DEFF Research Database (Denmark)

    Dittmann, Lars

    Awareness of energy consumption in communication networks such as the Internet is currently gaining momentum as it is commonly acknowledged that increased network capacity (currently driven by video applications) requires significant more electrical power. This paper stresses the importance...

  4. The Upgrade Programme for the Structural Biology beamlines at the European Synchrotron Radiation Facility – High throughput sample evaluation and automation

    International Nuclear Information System (INIS)

    Theveneau, P; Baker, R; Barrett, R; Beteva, A; Bowler, M W; Carpentier, P; Caserotto, H; Sanctis, D de; Dobias, F; Flot, D; Guijarro, M; Giraud, T; Lentini, M; Leonard, G A; Mattenet, M; McSweeney, S M; Morawe, C; Nurizzo, D; McCarthy, A A; Nanao, M

    2013-01-01

    Automation and advances in technology are the key elements in addressing the steadily increasing complexity of Macromolecular Crystallography (MX) experiments. Much of this complexity is due to the inter-and intra-crystal heterogeneity in diffraction quality often observed for crystals of multi-component macromolecular assemblies or membrane proteins. Such heterogeneity makes high-throughput sample evaluation an important and necessary tool for increasing the chances of a successful structure determination. The introduction at the ESRF of automatic sample changers in 2005 dramatically increased the number of samples that were tested for diffraction quality. This 'first generation' of automation, coupled with advances in software aimed at optimising data collection strategies in MX, resulted in a three-fold increase in the number of crystal structures elucidated per year using data collected at the ESRF. In addition, sample evaluation can be further complemented using small angle scattering experiments on the newly constructed bioSAXS facility on BM29 and the micro-spectroscopy facility (ID29S). The construction of a second generation of automated facilities on the MASSIF (Massively Automated Sample Screening Integrated Facility) beam lines will build on these advances and should provide a paradigm shift in how MX experiments are carried out which will benefit the entire Structural Biology community.

  5. Kinematic mounting systems for NSLS beamlines and experiments

    International Nuclear Information System (INIS)

    Oversluizen, T.; Stoeber, W.; Johnson, E.D.

    1991-01-01

    Methods for kinematically mounting equipment are well established, but applications at synchrotron radiation facilities are subject to constraints not always encountered in more traditional laboratory settings. Independent position adjustment of beamline components can have significant benefits in terms of minimizing time spent aligning, and maximizing time spent acquiring data. In this paper, we use examples taken from beamlines at the NSLS to demonstrate approaches for optimization of the reproducibility, stability, excursion, and set-up time for various situations. From our experience, we extract general principles which we hope will be useful for workers at other synchrotron radiation facilities. 7 refs., 4 figs

  6. Electronic remote blood issue: a combination of remote blood issue with a system for end-to-end electronic control of transfusion to provide a "total solution" for a safe and timely hospital blood transfusion service.

    Science.gov (United States)

    Staves, Julie; Davies, Amanda; Kay, Jonathan; Pearson, Oliver; Johnson, Tony; Murphy, Michael F

    2008-03-01

    The rapid provision of red cell (RBC) units to patients needing blood urgently is an issue of major importance in transfusion medicine. The development of electronic issue (sometimes termed "electronic crossmatch") has facilitated rapid provision of RBC units by avoidance of the serologic crossmatch in eligible patients. A further development is the issue of blood under electronic control at blood refrigerator remote from the blood bank. This study evaluated a system for electronic remote blood issue (ERBI) developed as an enhancement of a system for end-to-end electronic control of hospital transfusion. Practice was evaluated before and after its introduction in cardiac surgery. Before the implementation of ERBI, the median time to deliver urgently required RBC units to the patient was 24 minutes. After its implementation, RBC units were obtained from the nearby blood refrigerator in a median time of 59 seconds (range, 30 sec to 2 min). The study also found that unused requests were reduced significantly from 42 to 20 percent, the number of RBC units issued reduced by 52 percent, the number of issued units that were transfused increased from 40 to 62 percent, and there was a significant reduction in the workload of both blood bank and clinical staff. This study evaluated a combination of remote blood issue with an end-to-end electronically controlled hospital transfusion process, ERBI. ERBI reduced the time to make blood available for surgical patients and improved the efficiency of hospital transfusion.

  7. Nuclear resonant scattering beamline at SPring-8

    Energy Technology Data Exchange (ETDEWEB)

    Harami, Taikan [Japan Atomic Energy Research Inst., Kamigori, Hyogo (Japan). Kansai Research Establishment

    1996-04-01

    Mainly by Japan Atomic Energy Research Institute, the Institute of Physical and Chemical Research and Japan Synchrotron Radiation Research Institute, the construction of the Super Photon ring-8 GeV (SPring-8) which is the large scale synchrotron radiation facility for a high luminance light source placing emphasis on short wavelength region (shorter than about 1 nm) is in progress at the Harima Science Park City, Hyogo Prefecture. The features of the SPring-8 are the high luminance of light, the good parallelism and directionality of light, the quasi-monochromatic light with variable wavelength, and the possibility of design from straight polarization to circular polarization. The injection system that accelerates electrons up to 8 GeV and the storage ring storing the 8 GeV electrons for long hours, and 61 beamlines are explained. The manufacture of the nuclear resonant scattering beamline as the beamline for joint utilization was begun. Its transport channel and the experiment hutch are shown. By the features of undulator synchrotron radiation, the research on the matters with small recoilless fraction such as biological substances, liquid, gas and others and the research on time-dependent phenomena become feasible anew. The research on the dynamic structural analysis of heme protein is planned. (K.I.)

  8. Beamline for Schools 2016: How to be a CERN scientist

    CERN Document Server

    2016-01-01

    Two teams of high-school students from the UK and Poland had the opportunity to conduct their own experiments at a fully equipped CERN beamline.   Students from the 2016 Beamline for Schools competition working on their experiment. (Image: Noemí Carabán Gonzalez/CERN) Two teams of high-school students from the UK and Poland had the opportunity to conduct their own experiments at a fully equipped CERN beamline, after winning the Beamline for Schools competition. The teams, ”Pyramid Hunters” from Poland and “Relatively Special” from the United Kingdom, spent 10 days at CERN conducting the experiments they had dreamt up in their winning proposals. The Beamline for Schools competition gives high-school students the chance to run an experiment on a fully equipped CERN beamline, in the same way researchers do at the Large Hadron Collider and other CERN facilities every day. To know more about their stay at CERN and the experiments they&r...

  9. The microspectroscopy beamline for the Australian synchrotron project

    International Nuclear Information System (INIS)

    Boldeman, J.W.; Ryan, C.; Cohen, D.D.

    2005-01-01

    A new multi-million dollar synchrotron facility is currently being built in Clayton, Victoria. This is a 3GeV electron machine, it will be a world class machine and contain state of the art beamline facilities for both Australian and overseas scientists. It is due for completion in mid-2007. This specialised beamline will provide sub-micron spatial resolution with the highest flux possible. It will combine 2D mapping with micro X-ray fluorescence (μ-XRF), micro X-ray absorption near edge spectroscopy (μ-XANES) and micro X-ray absorption fine structure spectroscopy (μ-XAFS) for elemental and chemical analysis to solve scientific problems that can only be understood using X-ray beams with sub-micron resolutions. In this paper we describe some key beamline components and give details about their performance specifications. 7 refs., 4 figs.; 1 tab

  10. The BEAR Beamline at Elettra

    International Nuclear Information System (INIS)

    Nannarone, S.; Pasquali, L.; Selvaggi, G.; Borgatti, F.; DeLuisa, A.; Doyle, B.P.; Gazzadi, G.C.; Giglia, A.; Finetti, P.; Pedio, M.; Mahne, N.; Naletto, G.; Pelizzo, M.G.; Tondello, G.

    2004-01-01

    The BEAR (Bending Magnet for Emission Absorption and Reflectivity) beamline is installed at the right exit of the 8.1 bending magnet at ELETTRA. The beamline - in operation since January 2003 - delivers linear and circularly polarized radiation in the 5 - 1600 eV energy range. The experimental station is composed of a UHV chamber for reflectivity, absorption, fluorescence and angle resolved photoemission measurements and a UHV chamber for in-situ sample preparation

  11. A hard X-ray nanoprobe beamline for nanoscale microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Winarski, Robert P., E-mail: winarski@anl.gov; Holt, Martin V. [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60441 (United States); Rose, Volker [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60441 (United States); Fuesz, Peter; Carbaugh, Dean; Benson, Christa; Shu, Deming; Kline, David; Stephenson, G. Brian; McNulty, Ian [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60441 (United States); Maser, Jörg [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60441 (United States)

    2012-11-01

    The Hard X-ray Nanoprobe Beamline is a precision platform for scanning probe and full-field microscopy with 3–30 keV X-rays. A combination of high-stability X-ray optics and precision motion sensing and control enables detailed studies of the internal features of samples with resolutions approaching 30 nm. The Hard X-ray Nanoprobe Beamline (or Nanoprobe Beamline) is an X-ray microscopy facility incorporating diffraction, fluorescence and full-field imaging capabilities designed and operated by the Center for Nanoscale Materials and the Advanced Photon Source at Sector 26 of the Advanced Photon Source at Argonne National Laboratory. This facility was constructed to probe the nanoscale structure of biological, environmental and material sciences samples. The beamline provides intense focused X-rays to the Hard X-ray Nanoprobe (or Nanoprobe) which incorporates Fresnel zone plate optics and a precision laser sensing and control system. The beamline operates over X-ray energies from 3 to 30 keV, enabling studies of most elements in the periodic table, with a particular emphasis on imaging transition metals.

  12. Unmanned Aircraft Systems Detect and Avoid System: End-to-End Verification and Validation Simulation Study of Minimum Operations Performance Standards for Integrating Unmanned Aircraft into the National Airspace System

    Science.gov (United States)

    Ghatas, Rania W.; Jack, Devin P.; Tsakpinis, Dimitrios; Sturdy, James L.; Vincent, Michael J.; Hoffler, Keith D.; Myer, Robert R.; DeHaven, Anna M.

    2017-01-01

    As Unmanned Aircraft Systems (UAS) make their way to mainstream aviation operations within the National Airspace System (NAS), research efforts are underway to develop a safe and effective environment for their integration into the NAS. Detect and Avoid (DAA) systems are required to account for the lack of "eyes in the sky" due to having no human on-board the aircraft. The technique, results, and lessons learned from a detailed End-to-End Verification and Validation (E2-V2) simulation study of a DAA system representative of RTCA SC-228's proposed Phase I DAA Minimum Operational Performance Standards (MOPS), based on specific test vectors and encounter cases, will be presented in this paper.

  13. Safety and efficacy of the NiTi Shape Memory Compression Anastomosis Ring (CAR/ColonRing) for end-to-end compression anastomosis in anterior resection or low anterior resection.

    Science.gov (United States)

    Kang, Jeonghyun; Park, Min Geun; Hur, Hyuk; Min, Byung Soh; Lee, Kang Young; Kim, Nam Kyu

    2013-04-01

    Compression anastomoses may represent an improvement over traditional hand-sewn or stapled techniques. This prospective exploratory study aimed to assess the efficacy and complication rates in patients undergoing anterior resection (AR) or low anterior resection (LAR) anastomosed with a novel end-to-end compression anastomosis ring, the ColonRing. In all, 20 patients (13 male) undergoing AR or LAR were enrolled to be anastomosed using the NiTi Shape Memory End-to-End Compression Anastomosis Ring (NiTi Medical Technologies Ltd, Netanya, Israel). Demographic, intraoperative, and postoperative data were collected. Patients underwent AR (11/20) or LAR using laparoscopy (75%), robotic (10%) surgery, or an open laparotomy (15%) approach, with a median anastomotic level of 14.5 cm (range, 4-25 cm). Defunctioning loop ileostomies were formed in 6 patients for low anastomoses. Surgeons rated the ColonRing device as either easy or very easy to use. One patient developed an anastomotic leakage in the early postoperative period; there were no late postoperative complications. Mean time to passage of first flatus and commencement of oral fluids was 2.5 days and 3.2 days, respectively. Average hospital stay was 12.6 days (range, 8-23 days). Finally, the device was expelled on average 15.3 days postoperatively without difficulty. This is the first study reporting results in a significant number of LAR patients and the first reported experience from South Korea; it shows that the compression technique is surgically feasible, easy to use, and without significant complication rates. A large randomized controlled trial is warranted to investigate the benefits of the ColonRing over traditional stapling techniques.

  14. Efficacy and safety of a NiTi CAR 27 compression ring for end-to-end anastomosis compared with conventional staplers: A real-world analysis in Chinese colorectal cancer patients

    Science.gov (United States)

    Lu, Zhenhai; Peng, Jianhong; Li, Cong; Wang, Fulong; Jiang, Wu; Fan, Wenhua; Lin, Junzhong; Wu, Xiaojun; Wan, Desen; Pan, Zhizhong

    2016-01-01

    OBJECTIVES: This study aimed to evaluate the safety and efficacy of a new nickel-titanium shape memory alloy compression anastomosis ring, NiTi CAR 27, in constructing an anastomosis for colorectal cancer resection compared with conventional staples. METHODS: In total, 234 consecutive patients diagnosed with colorectal cancer receiving sigmoidectomy and anterior resection for end-to-end anastomosis from May 2010 to June 2012 were retrospectively analyzed. The postoperative clinical parameters, postoperative complications and 3-year overall survival in 77 patients using a NiTi CAR 27 compression ring (CAR group) and 157 patients with conventional circular staplers (STA group) were compared. RESULTS: There were no statistically significant differences between the patients in the two groups in terms of general demographics and tumor features. A clinically apparent anastomotic leak occurred in 2 patients (2.6%) in the CAR group and in 5 patients (3.2%) in the STA group (p=0.804). These eight patients received a temporary diverting ileostomy. One patient (1.3%) in the CAR group was diagnosed with anastomotic stricture through an electronic colonoscopy after 3 months postoperatively. The incidence of postoperative intestinal obstruction was comparable between the two groups (p=0.192). With a median follow-up duration of 39.6 months, the 3-year overall survival rate was 83.1% in the CAR group and 89.0% in the STA group (p=0.152). CONCLUSIONS: NiTi CAR 27 is safe and effective for colorectal end-to-end anastomosis. Its use is equivalent to that of the conventional circular staplers. This study suggests that NiTi CAR 27 may be a beneficial alternative in colorectal anastomosis in Chinese colorectal cancer patients. PMID:27276395

  15. X-ray fluorescence in Member States (India): Micro-beam X-ray fluorescence spectroscopy using Indus-2 synchrotron radiation facility: beamline BL-16

    Energy Technology Data Exchange (ETDEWEB)

    Tiwari, M. K.; Lodha, G. S.; Deb, S.K., E-mail: mktiwari@rrcat.gov.in [Indus Synchrotrons Utilization Division, Raja Ramanna Centre for Advanced Technology, Indore-452013 (MP) (India)

    2014-02-15

    Indus-1 and Indus-2, are India’s national synchrotron radiation facilities located at Raja Ramanna Centre for Advanced Technology (RRCAT), Indore. Indus-1 is a 450 MeV electron storage ring which provides synchrotron radiation in the VUV soft x-ray range with a critical wavelength of 61 Å whereas Indus-2 is a 2.5 GeV, 300 mA synchrotron radiation machine with a critical wavelength of 2 Å for its bending magnet source. The Indus-2 is at present operating at 2.5 GeV, 100 mA in round-theclock operation mode. Both synchrotron sources exist in the same premises of RRCAT, Indore and have very good air/rail connectivities with major cities of India. The RRCAT centre also fosters research and development activities in the fields of particle accelerators, Lasers and related advanced technologies like cryogenics, ultra high vacuum, superconducting cavities, RF power, magnet and their application in different fields of science, thus the centre provides a unique platform covering a wide range of experiments for the synchrotron users in the Indian subcontinent.

  16. Insertion devices and beamlines for the proposed Australian synchrotron light source

    International Nuclear Information System (INIS)

    Garrett, R.F.; Boldeman, J.W.

    1999-01-01

    Full text: The proposed Australian synchrotron light source, Boomerang, is a third generation 3 GeV storage ring which is designed to provide for the great majority of Australian requirements for synchrotron radiation well into the next century. The storage ring could accommodate up to 60 experimental stations, including beamlines from 9 insertion devices, which far exceeds the projected Australian requirements over the life of the facility. Undulator radiation will be available up to 20 keV. The first phase construction of Boomerang includes funding for 9 beamlines, comprising 5 bending magnet and 4 insertion device beamlines. The beamline complement has been chosen to cater for approximately 95% of the current and projected Australian demand for synchrotron radiation over the first 5 years operation of the facility. Details will be shown of the performance of the proposed insertion devices, and the initial beamline complement will be presented

  17. A Remote and Virtual Synchrotron Beamline

    Science.gov (United States)

    Jackson, J. M.; Alp, E.; Sturhahn, W.

    2012-12-01

    National facilities offer one-of-a-kind opportunities to apply state-of-the-art experimental techniques to the pressing scientific problems of today. Yet, few students are able to experience research projects at national facilities due to limited accessibility caused in part by limited involvement in the local academic institution, constrained working areas at the experimental stations, and/or travel costs. We present a virtual and remote beam-line for Earth science studies using nuclear resonant and inelastic x-ray scattering methods at Sector 3 of the Advanced Photon Source at Argonne National Laboratory. Off-site students have the capability of controlling their measurements via secure internet connections and webcams. Students can access a 'view only mode' for ease of interaction and safety-control. More experienced users have exclusive control of the experiment and can remotely change variables within the experimental setup. Students may also access the virtual aspects these experiments by simulating certain conditions with our newly developed software. We evaluate such a tool by giving "before" and "after" assignments to students at different levels. These levels include high-school students from the Pasadena and greater Los Angeles area school districts, undergraduate students from Caltech's SURF/MURF program, and graduate students at Caltech. We specifically target underrepresented groups. Our results thus far show that the capabilities offered by our remote and virtual beamline show improved knowledge and understanding of applying experimental-based studies at the synchrotron to solve problems in the Earth sciences.

  18. Emittance Measurement for Beamline Extension at the PET Cyclotron

    Directory of Open Access Journals (Sweden)

    Sae-Hoon Park

    2016-01-01

    Full Text Available Particle-induced X-ray emission is used for determining the elemental composition of materials. This method uses low-energy protons (of several MeV, which can be obtained from high-energy (of tens MeV accelerators. Instead of manufacturing an accelerator for generating the MeV protons, the use of a PET cyclotron has been suggested for designing the beamline for multipurpose applications, especially for the PIXE experiment, which has a dedicated high-energy (of tens MeV accelerator. The beam properties of the cyclotron were determined at this experimental facility by using an external beamline before transferring the ion beam to the experimental chamber. We measured the beam profile and calculated the emittance using the pepper-pot method. The beam profile was measured as the beam current using a wire scanner, and the emittance was measured as the beam distribution at the beam dump using a radiochromic film. We analyzed the measurement results and are planning to use the results obtained in the simulations of external beamline and aligned beamline components. We will consider energy degradation after computing the beamline simulation. The experimental study focused on measuring the emittance from the cyclotron, and the results of this study are presented in this paper.

  19. EPICS data archiver at SSRF beamlines

    International Nuclear Information System (INIS)

    Hu Zheng; Mi Qingru; Zheng Lifang; Li Zhong

    2014-01-01

    The control system of SSRF (Shanghai Synchrotron Radiation Facility) is based on EPICS (Experimental Physics and Industrial Control System). Operation data storage for synchrotron radiation facility is important for its status monitoring and analysis. At SSRF, operation data used to be index files recorded by traditional EPICS Channel Archiver. Nevertheless, index files are not suitable for long-term maintenance and difficult for data analysis. Now, RDB Channel Archiver and MySQL are used for SSRF beamline operation data archiving, so as to promote the data storage reliability and usability. By applying a new uploading mechanism to RDB Channel Archiver, its writing performance is improved. A web-based GUI (Graphics User Interface) is also developed to make it easier to access database. (authors)

  20. SU-F-P-37: Implementation of An End-To-End QA Test of the Radiation Therapy Imaging, Planning and Delivery Process to Identify and Correct Possible Sources of Deviation

    International Nuclear Information System (INIS)

    Salinas Aranda, F; Suarez, V; Arbiser, S; Sansogne, R

    2016-01-01

    Purpose: To implement an end-to-end QA test of the radiation therapy imaging, planning and delivery process, aimed to assess the dosimetric agreement accuracy between planned and delivered treatment, in order to identify and correct possible sources of deviation. To establish an internal standard for machine commissioning acceptance. Methods: A test involving all steps of the radiation therapy: imaging, planning and delivery process was designed. The test includes analysis of point dose and planar dose distributions agreement between TPS calculated and measured dose. An ad hoc 16 cm diameter PMMA phantom was constructed with one central and four peripheral bores that can accommodate calibrated electron density inserts. Using Varian Eclipse 10.0 and Elekta XiO 4.50 planning systems, IMRT, RapidArc and 3DCRT with hard and dynamic wedges plans were planned on the phantom and tested. An Exradin A1SL chamber is used with a Keithley 35617EBS electrometer for point dose measurements in the phantom. 2D dose distributions were acquired using MapCheck and Varian aS1000 EPID.Gamma analysis was performed for evaluation of 2D dose distribution agreement using MapCheck software and Varian Portal Dosimetry Application.Varian high energy Clinacs Trilogy, 2100C/CD, 2000CR and low energy 6X/EX where tested.TPS-CT# vs. electron density table were checked for CT-scanners used. Results: Calculated point doses were accurate to 0.127% SD: 0.93%, 0.507% SD: 0.82%, 0.246% SD: 1.39% and 0.012% SD: 0.01% for LoX-3DCRT, HiX-3DCRT, IMRT and RapidArc plans respectively. Planar doses pass gamma 3% 3mm in all cases and 2% 2mm for VMAT plans. Conclusion: Implementation of a simple and reliable quality assurance tool was accomplished. The end-to-end proved efficient, showing excellent agreement between planned and delivered dose evidencing strong consistency of the whole process from imaging through planning to delivery. This test can be used as a first step in beam model acceptance for clinical

  1. Control and data acquisition system for the macromolecular crystallography beamline of SSRF

    International Nuclear Information System (INIS)

    Wang Qisheng; Huang Sheng; Sun Bo; Tang Lin; He Jianhua

    2012-01-01

    The macromolecular crystallography beamline BL17U1 of Shanghai Synchrotron Radiation Facility (SSRF) is an important platform for structure biological science. High performance of the beamline would benefit the users greatly in their experiment and data acquisition. To take full advantage of the state-of-the-art mechanical and physical design of the beamline, we have made a series of efforts to develop a robust control and data acquisition system, with user-friendly GUI. These were done by adopting EPICS and Blu-Ice systems on the BL17U1 beamline, with considerations on easy accommodation of new beeline components. In this paper, we report the integration of EPICS and Blu-Ice systems. By using the EPICS gateway interface and several new DHS, Blu-Ice was successfully established for the BL17U1 beamline. As a result, the experiment control and data acquisition system is reliable and functional for users. (authors)

  2. WIFIP: a web-based user interface for automated synchrotron beamlines.

    Science.gov (United States)

    Sallaz-Damaz, Yoann; Ferrer, Jean Luc

    2017-09-01

    The beamline control software, through the associated graphical user interface (GUI), is the user access point to the experiment, interacting with synchrotron beamline components and providing automated routines. FIP, the French beamline for the Investigation of Proteins, is a highly automatized macromolecular crystallography (MX) beamline at the European Synchrotron Radiation Facility. On such a beamline, a significant number of users choose to control their experiment remotely. This is often performed with a limited bandwidth and from a large choice of computers and operating systems. Furthermore, this has to be possible in a rapidly evolving experimental environment, where new developments have to be easily integrated. To face these challenges, a light, platform-independent, control software and associated GUI are required. Here, WIFIP, a web-based user interface developed at FIP, is described. Further than being the present FIP control interface, WIFIP is also a proof of concept for future MX control software.

  3. Recent Major Improvements to the ALS Sector 5 Macromolecular Crystallography Beamlines

    International Nuclear Information System (INIS)

    Morton, Simon A.; Glossinger, James; Smith-Baumann, Alexis; McKean, John P.; Trame, Christine; Dickert, Jeff; Rozales, Anthony; Dauz, Azer; Taylor, John; Zwart, Petrus; Duarte, Robert; Padmore, Howard; McDermott, Gerry; Adams, Paul

    2007-01-01

    Although the Advanced Light Source (ALS) was initially conceived primarily as a low energy (1.9GeV) 3rd generation source of VUV and soft x-ray radiation it was realized very early in the development of the facility that a multipole wiggler source coupled with high quality, (brightness preserving), optics would result in a beamline whose performance across the optimal energy range (5-15keV) for macromolecular crystallography (MX) would be comparable to, or even exceed, that of many existing crystallography beamlines at higher energy facilities. Hence, starting in 1996, a suite of three beamlines, branching off a single wiggler source, was constructed, which together formed the ALS Macromolecular Crystallography Facility. From the outset this facility was designed to cater equally to the needs of both academic and industrial users with a heavy emphasis placed on the development and introduction of high throughput crystallographic tools, techniques, and facilities--such as large area CCD detectors, robotic sample handling and automounting facilities, a service crystallography program, and a tightly integrated, centralized, and highly automated beamline control environment for users. This facility was immediately successful, with the primary Multiwavelength Anomalous Diffraction beamline (5.0.2) in particular rapidly becoming one of the foremost crystallographic facilities in the US--responsible for structures such as the 70S ribosome. This success in-turn triggered enormous growth of the ALS macromolecular crystallography community and spurred the development of five additional ALS MX beamlines all utilizing the newly developed superconducting bending magnets ('superbends') as sources. However in the years since the original Sector 5.0 beamlines were built the performance demands of macromolecular crystallography users have become ever more exacting; with growing emphasis placed on studying larger complexes, more difficult structures, weakly diffracting or smaller

  4. Rearrangement of potassium ions and Kv1.1/Kv1.2 potassium channels in regenerating axons following end-to-end neurorrhaphy: ionic images from TOF-SIMS.

    Science.gov (United States)

    Liu, Chiung-Hui; Chang, Hung-Ming; Wu, Tsung-Huan; Chen, Li-You; Yang, Yin-Shuo; Tseng, To-Jung; Liao, Wen-Chieh

    2017-10-01

    The voltage-gated potassium channels Kv1.1 and Kv1.2 that cluster at juxtaparanodal (JXP) regions are essential in the regulation of nerve excitability and play a critical role in axonal conduction. When demyelination occurs, Kv1.1/Kv1.2 activity increases, suppressing the membrane potential nearly to the equilibrium potential of K + , which results in an axonal conduction blockade. The recovery of K + -dependent communication signals and proper clustering of Kv1.1/Kv1.2 channels at JXP regions may directly reflect nerve regeneration following peripheral nerve injury. However, little is known about potassium channel expression and its relationship with the dynamic potassium ion distribution at the node of Ranvier during the regenerative process of peripheral nerve injury (PNI). In the present study, end-to-end neurorrhaphy (EEN) was performed using an in vivo model of PNI. The distribution of K + at regenerating axons following EEN was detected by time-of-flight secondary-ion mass spectrometry. The specific localization and expression of Kv1.1/Kv1.2 channels were examined by confocal microscopy and western blotting. Our data showed that the re-establishment of K + distribution and intensity was correlated with the functional recovery of compound muscle action potential morphology in EEN rats. Furthermore, the re-clustering of Kv1.1/1.2 channels 1 and 3 months after EEN at the nodal region of the regenerating nerve corresponded to changes in the K + distribution. This study provided direct evidence of K + distribution in regenerating axons for the first time. We proposed that the Kv1.1/Kv1.2 channels re-clustered at the JXP regions of regenerating axons are essential for modulating the proper patterns of K + distribution in axons for maintaining membrane potential stability after EEN.

  5. SU-F-J-150: Development of An End-To-End Chain Test for the First-In-Man MR-Guided Treatments with the MRI Linear Accelerator by Using the Alderson Phantom

    Energy Technology Data Exchange (ETDEWEB)

    Hoogcarspel, S; Kerkmeijer, L; Lagendijk, J; Van Vulpen, M; Raaymakers, B [University Medical Center Utrecht, Utrecht, Utrecht (Netherlands)

    2016-06-15

    The Alderson phantom is a human shaped quality assurance tool that has been used for over 30 years in radiotherapy. The phantom can provide integrated tests of the entire chain of treatment planning and delivery. The purpose of this research was to investigate if this phantom can be used to chain test a treatment on the MRI linear accelerator (MRL) which is currently being developed at the UMC Utrecht, in collaboration with Elekta and Philips. The latter was demonstrated by chain testing the future First-in-Man treatments with this system.An Alderson phantom was used to chain test an entire treatment with the MRL. First, a CT was acquired of the phantom with additional markers that are both visible on MR and CT. A treatment plan for treating bone metastases in the sacrum was made. The phantom was consecutively placed in the MRL. For MRI imaging, an 3D volume was acquired. The initially developed treatment plan was then simulated on the new MRI dataset. For simulation, both the MR and CT data was used by registering them together. Before treatment delivery a MV image was acquired and compared with a DRR that was calculated form the MR/CT registration data. Finally, the treatment was delivered. Figure 1 shows both the T1 weighted MR-image of the phantom and the CT that was registered to the MR image. Figure 2 shows both the calculated and measured MV image that was acquired by the MV panel. Figure 3 shows the dose distribution that was simulated. The total elapsed time for the entire procedure excluding irradiation was 13:35 minutes.The Alderson Phantom yields sufficient MR contrast and can be used for full MR guided radiotherapy treatment chain testing. As a result, we are able to perform an end-to-end chain test of the future First-in-Man treatments.

  6. More Than Bar Codes: Integrating Global Standards-Based Bar Code Technology Into National Health Information Systems in Ethiopia and Pakistan to Increase End-to-End Supply Chain Visibility.

    Science.gov (United States)

    Hara, Liuichi; Guirguis, Ramy; Hummel, Keith; Villanueva, Monica

    2017-12-28

    The United Nations Population Fund (UNFPA) and the United States Agency for International Development (USAID) DELIVER PROJECT work together to strengthen public health commodity supply chains by standardizing bar coding under a single set of global standards. From 2015, UNFPA and USAID collaborated to pilot test how tracking and tracing of bar coded health products could be operationalized in the public health supply chains of Ethiopia and Pakistan and inform the ecosystem needed to begin full implementation. Pakistan had been using proprietary bar codes for inventory management of contraceptive supplies but transitioned to global standards-based bar codes during the pilot. The transition allowed Pakistan to leverage the original bar codes that were preprinted by global manufacturers as opposed to printing new bar codes at the central warehouse. However, barriers at lower service delivery levels prevented full realization of end-to-end data visibility. Key barriers at the district level were the lack of a digital inventory management system and absence of bar codes at the primary-level packaging level, such as single blister packs. The team in Ethiopia developed an open-sourced smartphone application that allowed the team to scan bar codes using the mobile phone's camera and to push the captured data to the country's data mart. Real-time tracking and tracing occurred from the central warehouse to the Addis Ababa distribution hub and to 2 health centers. These pilots demonstrated that standardized product identification and bar codes can significantly improve accuracy over manual stock counts while significantly streamlining the stock-taking process, resulting in efficiencies. The pilots also showed that bar coding technology by itself is not sufficient to ensure data visibility. Rather, by using global standards for identification and data capture of pharmaceuticals and medical devices, and integrating the data captured into national and global tracking systems

  7. Effect of surface slope errors of the ellipsoidal mirror on the resolution of the PGM beamline at Indus-1

    International Nuclear Information System (INIS)

    Singh, M.R.; Mukund, R.; Sahni, V.C.

    1999-01-01

    The influence of geometrical shape errors and surface errors on the characteristics and performance of grazing incidence optics used in the design of beamlines at synchrotron radiation facilities is considered. The methodology adopted for the simulation of slope errors is described and results presented for the ellipsoidal focussing mirror used in the design of PGM beamline at Indus-1. (author)

  8. Radiation protection of a proton beamline at ELI-Beamlines

    Czech Academy of Sciences Publication Activity Database

    Bechet, Sabrina; Versaci, Roberto; Rollet, S.; Olšovcová, Veronika; Fajstavr, Antonín; Žáková, Martina; Margarone, Daniele

    2016-01-01

    Roč. 11, č. 12 (2016), 1-5, č. článku C12019. ISSN 1748-0221 R&D Projects: GA MŠk EF15_008/0000162 Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162 Institutional support: RVO:68378271 Keywords : models * simulations * wake-field acceleration Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.220, year: 2016

  9. ALS beamline design requirements: A guide for beamline designers

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This manual is written as a guide for researchers in designing beamlines and endstations acceptable for use at the ALS. It contains guidelines and policies related to personnel safety and equipment and vacuum protection. All equipment and procedures must ultimately satisfy the safety requirements set aside in the Lawrence Berkeley National Laboratory (LBNL) Health and Safety Manual (PUB-3000) which is available from the ALS User Office or on the World WideWeb from the LBNL Homepage (http:// www.lbl.gov).

  10. Design of the LBNF Beamline Target Station

    Energy Technology Data Exchange (ETDEWEB)

    Tariq, S. [Fermilab; Ammigan, K. [Fermilab; Anderson, K.; ; Buccellato, S. A. [Fermilab; Crowley, C. F. [Fermilab; Hartsell, B. D. [Fermilab; Hurh, P. [Fermilab; Hylen, J. [Fermilab; Kasper, P. [Fermilab; Krafczyk, G. E. [Fermilab; Lee, A. [Fermilab; Lundberg, B. [Fermilab; Reitzner, S. D. [Fermilab; Sidorov, V. [Fermilab; Stefanik, A. M. [Fermilab; Tropin, I. S. [Fermilab; Vaziri, K. [Fermilab; Williams, K. [Fermilab; Zwaska, R. M. [Fermilab; Densham, C. [RAL, Didcot

    2016-10-01

    The Long Baseline Neutrino Facility (LBNF) project will build a beamline located at Fermilab to create and aim an intense neutrino beam of appropriate energy range toward the DUNE detectors at the SURF facility in Lead, South Dakota. Neutrino production starts in the Target Station, which consists of a solid target, magnetic focusing horns, and the associated sub-systems and shielding infrastructure. Protons hit the target producing mesons which are then focused by the horns into a helium-filled decay pipe where they decay into muons and neutrinos. The target and horns are encased in actively cooled steel and concrete shielding in a chamber called the target chase. The reference design chase is filled with air, but nitrogen and helium are being evaluated as alternatives. A replaceable beam window separates the decay pipe from the target chase. The facility is designed for initial operation at 1.2 MW, with the ability to upgrade to 2.4 MW, and is taking advantage of the experience gained by operating Fermilab’s NuMI facility. We discuss here the design status, associated challenges, and ongoing R&D and physics-driven component optimization of the Target Station.

  11. TARA beamline and injection system

    International Nuclear Information System (INIS)

    Post, R.S.; Brindza, P.; Coleman, J.W.; Torti, R.P.; Blackfield, D.T.; Goodrich, P.

    1983-01-01

    The TARA beamline for neutral beam injection will permit one to three sources to fire into each plug (60 degree or optional 90 degree injection with respect to the TARA axis) or into each anchor (90 degree injection only). The sources, pre-aimed on their mounting plate at the NB test stand, may be fired into neutralizer ducts or optionally through a magnesium curtain, and the unneutralized fraction is dumped by the TARA fringing field onto a receiver plate. The beamline is housed in a cylindrical tank with the beam axis along the tank diameter at the midplane. The tank will be sorption pumped using LN + T/sub I/ or N/sub B/ and/or e-beam gettering. The beam burial tank contains sed arrays and a thin foil dump which reaches sufficiently high temperatures during the shot to boil out gas between shots

  12. The High Energy Materials Science Beamline (HEMS) at PETRA III

    International Nuclear Information System (INIS)

    Schell, Norbert; King, Andrew; Beckmann, Felix; Ruhnau, Hans-Ulrich; Kirchhof, Rene; Kiehn, Ruediger; Mueller, Martin; Schreyer, Andreas

    2010-01-01

    The HEMS Beamline at the German high-brilliance synchrotron radiation storage ring PETRA III is fully tunable between 30 and 250 keV and optimized for sub-micrometer focusing. Approximately 70 % of the beamtime will be dedicated to Materials Research. Fundamental research will encompass metallurgy, physics and chemistry with first experiments planned for the investigation of the relationship between macroscopic and micro-structural properties of polycrystalline materials, grain-grain-interactions, and the development of smart materials or processes. For this purpose a 3D-microsctructure-mapper has been designed. Applied research for manufacturing process optimization will benefit from high flux in combination with ultra-fast detector systems allowing complex and highly dynamic in-situ studies of micro-structural transformations, e.g. during welding processes. The beamline infrastructure allows accommodation of large and heavy user provided equipment. Experiments targeting the industrial user community will be based on well established techniques with standardized evaluation, allowing full service measurements, e.g. for tomography and texture determination. The beamline consists of a five meter in-vacuum undulator, a general optics hutch, an in-house test facility and three independent experimental hutches working alternately, plus additional set-up and storage space for long-term experiments. HEMS is under commissioning as one of the first beamlines running at PETRA III.

  13. Construction and characterization of a laser-driven proton beamline at GSI

    OpenAIRE

    Busold, Simon

    2014-01-01

    The thesis includes the first experiments with the new 100 TW laser beamline of the PHELIX laser facility at GSI Darmstadt to drive a TNSA (Target Normal Sheath Acceleration) proton source at GSI's Z6 experimental area. At consecutive stages a pulsed solenoid has been applied for beam transport and energy selection via chromatic focusing, as well as a radiofrequency cavity for energy compression of the bunch. This novel laser-driven proton beamline, representing a central experiment of the...

  14. The ELIMED transport and dosimetry beamline for laser-driven ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Romano, F., E-mail: francesco.romano@lns.infn.it [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Schillaci, F.; Cirrone, G.A.P.; Cuttone, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Scuderi, V. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); ELI-Beamlines Project, Institute of Physics ASCR, v.v.i. (FZU), 182 21 Prague (Czech Republic); Allegra, L.; Amato, A.; Amico, A.; Candiano, G.; De Luca, G.; Gallo, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Giordanengo, S.; Guarachi, L. Fanola [Istituto Nazionale di Fisica Nucleare, Sezione di Torino, Via P. Giuria 1, Torino (Italy); Universita' di Torino, Dipartimento di Fisica, Via P. Giuria 1, Torino (Italy); Korn, G. [ELI-Beamlines Project, Institute of Physics ASCR, v.v.i. (FZU), 182 21 Prague (Czech Republic); Larosa, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Leanza, R. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Universita' di Catania, Dipartimento di Fisica e Astronomia, Via S. Sofia 64, Catania (Italy); Manna, R.; Marchese, V. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Marchetto, F. [Istituto Nazionale di Fisica Nucleare, Sezione di Torino, Via P. Giuria 1, Torino (Italy); Margarone, D. [ELI-Beamlines Project, Institute of Physics ASCR, v.v.i. (FZU), 182 21 Prague (Czech Republic); and others

    2016-09-01

    A growing interest of the scientific community towards multidisciplinary applications of laser-driven beams has led to the development of several projects aiming to demonstrate the possible use of these beams for therapeutic purposes. Nevertheless, laser-accelerated particles differ from the conventional beams typically used for multiscipilinary and medical applications, due to the wide energy spread, the angular divergence and the extremely intense pulses. The peculiarities of optically accelerated beams led to develop new strategies and advanced techniques for transport, diagnostics and dosimetry of the accelerated particles. In this framework, the realization of the ELIMED (ELI-Beamlines MEDical and multidisciplinary applications) beamline, developed by INFN-LNS (Catania, Italy) and that will be installed in 2017 as a part of the ELIMAIA beamline at the ELI-Beamlines (Extreme Light Infrastructure Beamlines) facility in Prague, has the aim to investigate the feasibility of using laser-driven ion beams for multidisciplinary applications. In this contribution, an overview of the beamline along with a detailed description of the main transport elements as well as the detectors composing the final section of the beamline will be presented.

  15. MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments

    International Nuclear Information System (INIS)

    Gabadinho, José; Beteva, Antonia; Guijarro, Matias; Rey-Bakaikoa, Vicente; Spruce, Darren

    2010-01-01

    MxCuBE is a beamline control environment optimized for the needs of macromolecular crystallography. This paper describes the design of the software and the features that MxCuBE currently provides. The design and features of a beamline control software system for macromolecular crystallography (MX) experiments developed at the European Synchrotron Radiation Facility (ESRF) are described. This system, MxCuBE, allows users to easily and simply interact with beamline hardware components and provides automated routines for common tasks in the operation of a synchrotron beamline dedicated to experiments in MX. Additional functionality is provided through intuitive interfaces that enable the assessment of the diffraction characteristics of samples, experiment planning, automatic data collection and the on-line collection and analysis of X-ray emission spectra. The software can be run in a tandem client-server mode that allows for remote control and relevant experimental parameters and results are automatically logged in a relational database, ISPyB. MxCuBE is modular, flexible and extensible and is currently deployed on eight macromolecular crystallography beamlines at the ESRF. Additionally, the software is installed at MAX-lab beamline I911-3 and at BESSY beamline BL14.1

  16. Beamline 9.0.1 - a high-resolution undulator beamline for gas-phase spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Bozek, J.D.; Heimann, P.A.; Mossessian, D. [Ernest Orlando Lawrence Berkeley National Lab., CA (United States)

    1997-04-01

    Beamline 9.0.1 at the Advanced Light Source is an undulator beamline with a Spherical Grating Monochromator (SGM) which provides very high resolution and flux over the photon energy range 20-320eV. The beamline has been used primarily by the atomic and molecular science community to conduct spectroscopy experiments using electron, ion and fluorescence photon detection. A description of the beamline and its performance will be provided in this abstract.

  17. SPring-8 Structural Biology Beamlines / Current Status of Public Beamlines for Protein Crystallography at SPring-8

    International Nuclear Information System (INIS)

    Kawamoto, Masahide; Hasegawa, Kazuya; Shimizu, Nobutaka; Sakai, Hisanobu; Shimizu, Tetsuya; Nisawa, Atsushi; Yamamoto, Masaki

    2007-01-01

    SPring-8 has 2 protein crystallography beamlines for public use, BL38B1 (Structural Biology III) and BL41XU (Structural Biology I). The BL38B1 is a bending magnet beamline for routine data collection, and the BL41XU is an undulator beamline specially customized for micro beam and ultra-high resolutional experiment. The designs and the performances of each beamline are presented

  18. An object model for beamline descriptions

    International Nuclear Information System (INIS)

    Hill, B.W.; Martono, H.; Gillespie, J.S.

    1997-01-01

    Translation of beamline model descriptions between different accelerator codes presents a unique challenge due to the different representations used for various elements and subsystems. These differences range from simple units conversions to more complex translations involving multiple beamline components. A representation of basic accelerator components is being developed in order to define a meta-structure from which beamline models, in different codes, can be described and to facilitate the translation of models between these codes. Sublines of basic components will be used to represent more complex beamline descriptions and bridge the gap between codes which may represent a beamline element as a single entity, and those which use multiple elements to describe the same physical device. A C++ object model for supporting this beamline description and a grammar for describing beamlines in terms of these components is being developed. The object model will support a common graphic user interface and translation filters for representing native beamline descriptions for a variety of accelerator codes. An overview of our work on the object model for beamline descriptions is presented here. copyright 1997 American Institute of Physics

  19. TOWARD END-TO-END MODELING FOR NUCLEAR EXPLOSION MONITORING: SIMULATION OF UNDERGROUND NUCLEAR EXPLOSIONS AND EARTHQUAKES USING HYDRODYNAMIC AND ANELASTIC SIMULATIONS, HIGH-PERFORMANCE COMPUTING AND THREE-DIMENSIONAL EARTH MODELS

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, A; Vorobiev, O; Petersson, A; Sjogreen, B

    2009-07-06

    This paper describes new research being performed to improve understanding of seismic waves generated by underground nuclear explosions (UNE) by using full waveform simulation, high-performance computing and three-dimensional (3D) earth models. The goal of this effort is to develop an end-to-end modeling capability to cover the range of wave propagation required for nuclear explosion monitoring (NEM) from the buried nuclear device to the seismic sensor. The goal of this work is to improve understanding of the physical basis and prediction capabilities of seismic observables for NEM including source and path-propagation effects. We are pursuing research along three main thrusts. Firstly, we are modeling the non-linear hydrodynamic response of geologic materials to underground explosions in order to better understand how source emplacement conditions impact the seismic waves that emerge from the source region and are ultimately observed hundreds or thousands of kilometers away. Empirical evidence shows that the amplitudes and frequency content of seismic waves at all distances are strongly impacted by the physical properties of the source region (e.g. density, strength, porosity). To model the near-source shock-wave motions of an UNE, we use GEODYN, an Eulerian Godunov (finite volume) code incorporating thermodynamically consistent non-linear constitutive relations, including cavity formation, yielding, porous compaction, tensile failure, bulking and damage. In order to propagate motions to seismic distances we are developing a one-way coupling method to pass motions to WPP (a Cartesian anelastic finite difference code). Preliminary investigations of UNE's in canonical materials (granite, tuff and alluvium) confirm that emplacement conditions have a strong effect on seismic amplitudes and the generation of shear waves. Specifically, we find that motions from an explosion in high-strength, low-porosity granite have high compressional wave amplitudes and weak

  20. Beamlines on Indus-1 and Indus-2: present status

    International Nuclear Information System (INIS)

    Lodha, G.S.; Deb, S.K.

    2010-01-01

    Indus-1 (450 MeV) is an efficient synchrotron radiation (SR) source in the soft X-ray/vacuum ultra violet region of the electromagnetic spectrum. For Indus-1 the higher order energy contamination in soft X-ray region, heat load and radiation safety problems are also significantly low. At present five beamlines are operational. This SR source is a national science facility being used by various research group across the country. Strong efforts are underway to increase the user base of Indus-1. The talk presents some of the recent studies carried out using Indus-1. Indus-2 (2.5 GeV) synchrotron source is one of the most important accelerator based science facilities being setup in India. A few beamlines have been commissioned and are being used by researchers from different institutes. This talk gives present status of the various beamlines and experimental stations on Indus-2. It is envisaged that the atomic and molecular science community can actively participate in planning experiments on Indus-1 and Indus-2 and setup experimental stations on Indus-2. (author)

  1. Design and simulation of the nuSTORM pion beamline

    Energy Technology Data Exchange (ETDEWEB)

    Liu, A., E-mail: aoliu@fnal.gov; Neuffer, D.; Bross, A.

    2015-11-21

    The nuSTORM (neutrinos from STORed Muons) proposal presents a detailed design for a neutrino facility based on a muon storage ring, with muon decay in the production straight section of the ring providing well defined neutrino beams. The facility includes a primary high-energy proton beam line, a target station with pion production and collection, and a pion beamline for pion transportation and injection into a muon decay ring. The nuSTORM design uses “stochastic injection”, in which pions are directed by a chicane, referred to as the Orbit Combination Section (OCS), into the production straight section of the storage ring. Pions that decay within that straight section provide muons within the circulating acceptance of the ring. The design enables injection without kickers or a separate pion decay transport line. The beam line that the pions traverse before being extracted from the decay ring is referred to as the pion beamline. This paper describes the design and simulation of the pion beamline, and includes full beam dynamics simulations of the system.

  2. The ELSA laser beamline for electron polarization measurements via Compton backscattering

    Energy Technology Data Exchange (ETDEWEB)

    Switka, Michael; Hinterkeuser, Florian; Koop, Rebecca; Hillert, Wolfgang [Electron Stretcher Facility ELSA, Physics Institute of Bonn University (Germany)

    2016-07-01

    The Electron Stretcher Facility ELSA provides a spin polarized electron beam with energies of 0.5 - 3.2 GeV for double polarization hadron physics experiments. As of 2015, the laser beamline of the polarimeter based on Compton backscattering restarted operation. It consists of a cw disk laser with design total beam power of 40 W and features two polarized 515 nm photon beams colliding head-on with the stored electron beam in ELSA. The polarization measurement is based on the vertical profile asymmetry of the back-scattered photons, which is dependent on the polarization degree of the stored electron beam. After recent laser repairs, beamline and detector modifications, the properties of the beamline have been determined and first measurements of the electron polarization degree were conducted. The beamline performance and first measurements are presented.

  3. TIME-RESOLVED INFRARED SPECTROSCOPY IN THE U121R BEAMLINE AT THE NSLS

    International Nuclear Information System (INIS)

    CARR, G.L.; LAVEIGNE, J.D.; LOBO, R.P.S.M.; REITZE, D.H.; TANNER, D.B.

    1999-01-01

    A facility for performing time-resolved infrared spectroscopy has been developed at the NSLS, primarily at beamline U12IR. The pulsed IR light from the synchrotron is used to perform pump-probe spectroscopy. The authors present here a description of the facility and results for the relaxation of photoexcitations in both a semiconductor and superconductor

  4. Inelastic X-ray Scattering Beamline Collaborative Development Team Final Report

    International Nuclear Information System (INIS)

    Burns, Clement

    2008-01-01

    This is the final report for the project to create a beam line for inelastic x-ray scattering at the Advanced Photon Source. The facility is complete and operating well, with spectrometers for both high resolution and medium resolution measurements. With the advent of third generation synchrotron sources, inelastic x-ray scattering (IXS) has become a valuable technique to probe the electronic and vibrational states of a wide variety of systems of interest in physics, chemistry, and biology. IXS is a weak probe, and experimental setups are complex and require well-optimized spectrometers which need a dedicated beamline to function efficiently. This project was the result of a proposal to provide a world-class, user friendly beamline for IXS at the Advanced Photon Source. The IXS Collaborative Development Team (IXS-CDT) was formed from groups at the national laboratories and a number of different universities. The beamline was designed from the front end to the experimental stations. Two different experimental stations were provided, one for medium resolution inelastic x-ray scattering (MERIX) and a spectrometer for high resolution inelastic x-ray scattering (HERIX). Funding for this project came from several sources as well as the DOE. The beamline is complete with both spectrometers operating well. The facility is now open to the general user community and there has been a tremendous demand to take advantage of the beamline's capabilities. A large number of different experiments have already been carried out on the beamline. A detailed description of the beamline has been given in the final design report (FDR) for the beamline from which much of the material in this report came. The first part of this report contains a general overview of the project with more technical details given later.

  5. Beamline for Schools Safety Awareness Day

    CERN Multimedia

    Photo Service, CERN

    2014-01-01

    The first two teams to participate in CERN's Beamline for Schools project spent their first day at CERN at the Safety Training Center in Prévessin. They covered amongst others radiation protection, cryogenics and fire-fighting. The teams will spend the rest of the week at the T9 beamline.

  6. Radiation-resistant beamline components at LAMPF

    International Nuclear Information System (INIS)

    Macek, R.J.; Grisham, D.L.; Lambert, J.e.; Werbeck, R.

    1983-01-01

    A variety of highly radiation-resistant beamline components have been successfully developed at LAMPF primarily for use in the target cells and beam stop area of the intense proton beamline. Design features and operating experience are reviewed for magnets, instrumentation, targets, vacuum seals, vacuum windows, collimators, and beam stops

  7. Limiting effects in double EEX beamline

    Science.gov (United States)

    Ha, G.; Power, J. G.; Conde, M.; Doran, D. S.; Gai, W.

    2017-07-01

    The double emittance exchange (EEX) beamline is suggested to overcome the large horizontal emittance and transverse jitter issues associated with the single EEX beamline while preserving its powerful phase-space manipulation capability. However, the double EEX beamline also has potential limitations due to coherent synchrotron radiation (CSR) and transverse jitter. The former limitation arises because double EEX uses twice as many bending magnets as single EEX which means stronger CSR effects degrading the beam quality. The latter limitation arises because a longitudinal jitter in front of the first EEX beamline is converted into a transverse jitter in the middle section (between the EEX beamlines) which can cause beam loss or beam degradation. In this paper, we numerically explore the effects of these two limitations on the emittance and beam transport.

  8. Limiting effects in double EEX beamline

    International Nuclear Information System (INIS)

    Ha, G; Power, J G; Conde, M; Doran, D S; Gai, W

    2017-01-01

    The double emittance exchange (EEX) beamline is suggested to overcome the large horizontal emittance and transverse jitter issues associated with the single EEX beamline while preserving its powerful phase-space manipulation capability. However, the double EEX beamline also has potential limitations due to coherent synchrotron radiation (CSR) and transverse jitter. The former limitation arises because double EEX uses twice as many bending magnets as single EEX which means stronger CSR effects degrading the beam quality. The latter limitation arises because a longitudinal jitter in front of the first EEX beamline is converted into a transverse jitter in the middle section (between the EEX beamlines) which can cause beam loss or beam degradation. In this paper, we numerically explore the effects of these two limitations on the emittance and beam transport. (paper)

  9. CAT Guide and Beamline Directory. A key to APS Collaborative Access Teams

    International Nuclear Information System (INIS)

    1999-01-01

    The Advanced Photon Source (APS), a national user facility for synchrotrons radiation research, is located at Argonne National Laboratory, approximately 25 miles southwest of Chicago, Illinois. The APS is considered a third-generation synchrotrons radiation facility (specifically designed to accommodate insertion devices to serve as radiation sources) and is one of three such facilities in the world. Currently, it is the most brilliant source in the United States for research in such diverse fields as biology, medicine, materials science, chemistry, geology, agriculture and soil science, physics, and manufacturing technology. Researchers use the APS either as members of Collaborative Access Teams (CATS) or as Independent Investigators (IIs). CATS are responsible for designing, building, and operating beamlines in one or more sectors, each sector consisting of an insertion-device (ID) beamline and a bending-magnet (BM) beamline. Each beamline is designed to accommodate a specific type of research program(s) and is optimized accordingly. CAT members are entitled to use 75% of the available beam time to pursue CAT research goals. The remaining 25% of the available beam time must be made available to IIs. This document was written to help prospective IIs determine which beamlines are suitable for their specific experiments

  10. High resolution inner-shell spectroscopies of atoms and molecules in gas phase using the soft x-ray photochemistry beamline at SPring-8

    International Nuclear Information System (INIS)

    Ueda, Kiyoshi

    2003-01-01

    This article describes recent activities on inner-shell spectroscopies of atoms and molecules on beamline 27SU, nicknamed soft X-ray photochemistry beamline, at SPring-8, an 8-GeV synchrotron radiation facility in Japan. This beamline provides linearly polarized monochromatic soft X-rays at the resolution higher than 10,000. The end station is designed so that one can perform various kinds of excitation and de-excitation spectroscopies as well as coincidence spectroscopies. Following the description of the beamline and the end station, we present recent results for inner-shell spectroscopies on Ne, CO 2 , BF 3 , and CF 4 . Emphasis is given to illustrate the strategy of the research on this beamline and performance of the beamline and the end station. (author)

  11. Beamline for low-energy transport of highly charged ions at HITRAP

    International Nuclear Information System (INIS)

    Andelkovic, Z.; Herfurth, F.; Kotovskiy, N.; König, K.; Maaß, B.; Murböck, T.; Neidherr, D.; Schmidt, S.; Steinmann, J.; Vogel, M.; Vorobjev, G.

    2015-01-01

    A beamline for transport of highly charged ions with energies as low as a few keV/charge has been constructed and commissioned at GSI. Complementary to the existing infrastructure of the HITRAP facility for deceleration of highly charged ions from the GSI accelerator, the new beamline connects the HITRAP ion decelerator and an EBIT with the associated experimental setups. Therefore, the facility can now transport the decelerated heavy highly charged ions to the experiments or supply them offline with medium-heavy highly charged ions from the EBIT, both at energies as low as a few keV/charge. Here we present the design of the 20 m long beamline with the corresponding beam instrumentation, as well as its performance in terms of energy and transport efficiency

  12. Microspectroscopy At Beamline 73 MAX-lab

    International Nuclear Information System (INIS)

    Engdahl, Anders

    2010-01-01

    Presentation of some projects at the infrared microspectroscopy experimental station at beamline 73 MAX-lab. Among the subjects are found identification of organic residues in fossil material and examination of the chemistry in an old oak wood wreck.

  13. A Test Beamline on Diamond Light Source

    International Nuclear Information System (INIS)

    Sawhney, K. J. S.; Dolbnya, I. P.; Tiwari, M. K.; Alianelli, L.; Scott, S. M.; Preece, G. M.; Pedersen, U. K.; Walton, R. D.

    2010-01-01

    A Test beamline B16 has been built on the 3 GeV Diamond synchrotron radiation source. The beamline covers a wide photon energy range from 2 to 25 keV. The beamline is highly flexible and versatile in terms of the available beam size (a micron to 100 mm) and the range of energy resolution and photon flux; by virtue of its several operational modes, and the different inter-changeable instruments available in the experiments hutch. Diverse experimental configurations can be flexibly configured using a five-circle diffractometer, a versatile optics test bench, and a suite of detectors. Several experimental techniques including reflectivity, diffraction and imaging are routinely available. Details of the beamline and its measured performance are presented.

  14. Doublet III beamline: as-built

    International Nuclear Information System (INIS)

    Harder, C.R.; Holland, M.M.; Parker, J.W.; Gunn, J.; Resnick, L.

    1980-03-01

    In order to fully exploit Doublet III capabilities and to study new plasma physics regimes, a Neutral Beam Injector System has been constructed. Initially, a two beamline system will supply 7 MW of heat to the plasma. The system is currently being expanded to inject approx. 20 MW of power (6 beamlines). Each beamline is equipped with two Lawrence Berkeley Laboratory type rectangular ion sources with 10 cm x 40 cm extraction grids. These sources will accelerate hydrogen ions to 80 keV, with extracted beam currents in excess of 80 A per source expected. The first completed source is currently being tested and conditioned on the High Voltage Test Stand at Lawrence Livermore Laboratory. This paper pictorially reviews the as-built Doublet III neutral beamline with emphasis on component relation and configuration relative to spatial and source imposed design constraints

  15. Solutions to mitigate heat loads due to electrons on sensitive components of ITER HNB beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Sartori, Emanuele, E-mail: emanuele.sartori@gmail.com [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), C.so Stati Uniti 4, 35127 Padova (Italy); Veltri, Pierluigi; Dalla Palma, Mauro; Agostinetti, Piero [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), C.so Stati Uniti 4, 35127 Padova (Italy); Hemsworth, Ronald; Singh, Mahendrajit [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Serianni, Gianluigi [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), C.so Stati Uniti 4, 35127 Padova (Italy)

    2016-11-01

    Highlights: • Energetic electrons leaking out of the ITER HNB accelerator are simulated. • Electrons generated along the ITER HNB beamline are simulated. • Heat loads and heat load maps on cryopumps are calculated for ITER HNB and test facility. • Protection solutions that will be installed are presented and their effect discussed. - Abstract: The operation of neutral beam injectors for plasma heating and current drive in a fusion device provides challenges in the thermal management of beamline components. Sensitive components such as the cryogenic pumps at beamline periphery shall be protected from the heat flux due to stray electrons. These are emitted by the negative ion accelerator or generated along the beamline by interaction of fast electrons, ions or atoms with background gas and surfaces. In this article the case of the ITER Heating Neutral Beam (HNB) and its test facility MITICA is discussed, for which the beam parameters and the required pulse length of one hour is a major leap forward with respect to the present experience with neutral beam systems. The engineering solutions adopted for effective cryopump protection against the heat load from electrons are described. The use of three-dimensional numerical simulations of particle trajectories in the complex geometry of the beamline was needed for the quantitative estimations of the heat loads. The presented solutions were optimized to minimize the impact on gas pumping and on the functionality of other components.

  16. New beamline dedicated to solution scattering from biological macromolecules at the ESRF

    International Nuclear Information System (INIS)

    Pernot, P; Theveneau, P; Giraud, T; Fernandes, R Nogueira; Nurizzo, D; Spruce, D; Surr, J; McSweeney, S; Round, A; Felisaz, F; Foedinger, L; Gobbo, A; Huet, J; Villard, C; Cipriani, F

    2010-01-01

    The new bio-SAXS beamline (ID14-3 at the ESRF, Grenoble, France) is dedicated exclusively to small-angle scattering experiments of biological macromolecules in solution and has been in user operation since November 2008. Originally a protein crystallography beamline, ID14-3 was refurbished, still as a part of the ESRF Structural Biology group, with the main aim to provide a facility with 'quick and easy' access to satisfy rapidly growing demands from crystallographers, biochemists and structural biologists. The beamline allows manual and automatic sample loading/unloading, data collection, processing (conversion of a 2D image to a normalized 1D X-ray scattering profile) and analysis. The users obtain on-line standard data concerning the size (radius of gyration, maximum dimension and volume) and molecular weight of samples which allow on-the fly ab-inito shape reconstruction in order to provide feedback enabling the data collection strategies to be optimized. Automation of sample loading is incorporated on the beamline using a device constructed in collaboration between the EMBL (Grenoble and Hamburg outstations) and the ESRF. Semi/automated data analysis is implemented following the model of the SAXS facility at X33, EMBL Hamburg. This paper describes the bio-SAXS beamline and set-up characteristics together with the examples of user data obtained.

  17. SR TXRF: performances and perspectives of a dedicated synchrotron beamline

    International Nuclear Information System (INIS)

    Comin, F.; Apostolo, G.

    2000-01-01

    In principle the brilliance of synchrotron radiation x-ray beams combined with a high degree of linear polarization allows to reach at the same time low LLDs, mapping of the impurity distribution and chemical identification for elements as light as Na. The TXRF facility at the European synchrotron radiation facility is installed along a beamline dedicated to industry and is designed to reach ultimate detection limits of 6 x 10 7 at/cm 2 in selected areas, or to map the concentration of contaminants with LLD in the scale 10 9 at/cm 2 . In the present configuration the facility works in vacuum with a single element detector. Loading, unloading and pump down of wafers is completely automatic. Typical DDLs are of few 10 9 at/cm 2 for Na and Al and 10 8 at/cm 2 for transition metals. Absorption spectra (XANES and EXAFS) of TM help in the defining the chemistry of the contaminant. (author)

  18. MARS, a new beamline for radioactive matter studies at SOLEIL

    International Nuclear Information System (INIS)

    Solari, Pier Lorenzo; Schlutig, Sandrine; Hermange, Herve; Sitaud, Bruno

    2009-01-01

    MARS (Multi Analyses on Radioactive Samples) beamline is the hard X-ray bending magnet beamline dedicated to the study of radioactive matter of the new French synchrotron SOLEIL. The beamline, which has been built thanks to a close partnership and support by the CEA, has been designed to provide X-rays in the energy range of 3.5 keV to 35 keV. This allows to encompass M and L absorption edges of actinides, as well as K edges of transition metals (that are present in alloys and fuel claddings) up to heavy halogens, rare gases and alkalis (fission products in nuclear fuels). The MARS project aims to extend the possibilities of synchrotron based X-ray characterizations towards a wider variety of radioactive elements and a wider variety of techniques than what is currently available at other facilities. Thus, its specific and innovative infrastructure has been optimized in order to carry out analyses on materials with activities up to 18.5 GBq per sample for α and β emitters and 2 GBq for γ and n emitters. So, today, more than 70 different elements and more than 350 different isotopes have been proposed for studies on the beamline by the involved user community. The arrangement of the different elements in the optics hutch is based on an original scheme which permits to have two alternative optical configurations (monochromatic or dispersive) depending on the nature of experiments to be performed. At least three main techniques are progressively being proposed on the three complementary end-stations located in the experimental hutch: transmission and high resolution powder diffraction (TXRD and HRXRD), standard and dispersive X-ray absorption spectroscopy (XAS and EDXAS) and X-ray fluorescence (XRF). In addition, by using the KB optics, a micro-focused beam will be available on the second station of the monochromatic branch. The beamline is currently under commissioning. The first two experimental stations, using the monochromatic branch, are scheduled to be

  19. The protein crystallography beamline BW6 at DORIS - automatic operation and high-throughput data collection

    CERN Document Server

    Blume, H; Bourenkov, G P; Kosciesza, D; Bartunik, H D

    2001-01-01

    The wiggler beamline BW6 at DORIS has been optimized for de-novo solution of protein structures on the basis of MAD phasing. Facilities for automatic data collection, rapid data transfer and storage, and online processing have been developed which provide adequate conditions for high-throughput applications, e.g., in structural genomics.

  20. Construction Status of the Beamline for Radio-Isotope Production in the Korea Multi-purpose Accelerator Complex

    Energy Technology Data Exchange (ETDEWEB)

    Chung, B. H.; Yoon, S. P.; Seol, K. T.; Kim, H. S.; Kwon, H. J.; Cho, Y. S. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The 100-MeV beamline consist of 5 target room, a TR 103 as one of these is operating beamline, and a TR 101 as the other beamline is under construction as shown in Fig. 1. The TR 101 as beamline target room will be used for the high value-added medical isotope production and increased utilization of the proton accelerator. The optical system of the beamline consisted of dipole and quadrupole, and it included beam position monitor (BPM) and current transformer (CT) for beam diagnostics. The beamline was inserted into the carbon block and the aluminum collimator, the end of pipe as beam window was used for the aluminum to reduce the radioactive of materials. The target transfer equipment is being installed for RI production. The RI Beamline was aligned using the laser tracker, and vacuum leak was not detected by the helium leak detector. This facility is expected to the high value-added medical isotope production and increased utilization of the proton accelerator.

  1. Motion control system of MAX IV Laboratory soft x-ray beamlines

    International Nuclear Information System (INIS)

    Sjöblom, Peter; Lindberg, Mirjam; Forsberg, Johan; Persson, Andreas G.; Urpelainen, Samuli; Såthe, Conny

    2016-01-01

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  2. A pixel detector for the protein crystallography beamline at the SLS

    CERN Document Server

    Brönnimann, C; Eikenberry, E F; Fischer, P; Florin, S; Horisberger, R P; Lindner, Manfred; Schmitt, B; Schulze, C

    2002-01-01

    At the Paul Scherrer Institute a new synchrotron light source is currently under construction, the Swiss Light Source (SLS), which will be operational in summer 2001. Among the first beamlines is a high brightness, micro-focusing protein crystallography beamline. It will be equipped with a pixel detector, which has several features of interest for the next generation of protein crystallography detectors. The point spread function and the effect of charge sharing was measured with a prototype detector in a test experiment at the European Synchrotron Radiation Facility in Grenoble. The concepts of the SLS pixel detector is presented as well as test results from radiation hard prototype chips.

  3. Motion control system of MAX IV Laboratory soft x-ray beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Sjöblom, Peter, E-mail: peter.sjoblom@maxlab.lu.se; Lindberg, Mirjam, E-mail: mirjam.lindberg@maxlab.lu.se; Forsberg, Johan, E-mail: johan.forsberg@maxlab.lu.se; Persson, Andreas G., E-mail: andreas-g.persson@maxlab.lu.se; Urpelainen, Samuli, E-mail: samuli.urpelainen@maxlab.lu.se; Såthe, Conny, E-mail: conny.sathe@maxlab.lu.se [MAX IV Laboratory, Photongatan 2, 225 92 Lund (Sweden)

    2016-07-27

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  4. Baking controller for synchrotron beamline vacuum systems

    International Nuclear Information System (INIS)

    Garg, C.K.; Kane, S.R.; Dhamgaye, V.P.

    2003-01-01

    The 2.5 GeV electron storage ring Indus-2 is a hard X-ray Synchrotron Radiation (SR) Source. Nearly 27 beamlines will be installed on Indus-2 and they will cater to different experiments and applications. Most of the beamlines will be in Ultra High Vacuum (UHV) the only exception being hard X-rays beamlines. However the front ends of all the beamlines will be in UHV. Practicing UHV requires efforts and patience. Evacuating any chamber, volume gases can be removed easily. However, outgassing phenomena like desorption, diffusion and permeation restricts the system to attain UHV. All processes except the volume gas removal are temperature dependent. At ambient temperature, gas pressure decreases so slowly that outgassing limit (i.e. 10 -10 1/s/cm 2 ) can hardly be achieved on a practical time scale. Also there are three orders of magnitude difference in outgassing between baked and unbaked systems. Depending on the vacuum chamber and the components inside it, the thermal outgassing (baking) of system is required and can be done at various temperatures between 150 degC to 450 deg C. For whole baking cycle, constant monitoring and controlling of the systems is required which takes tens of hours. This paper describes the automation for such baking system, which will be used for SR beamlines

  5. Modeling of X-ray beamlines and devices

    International Nuclear Information System (INIS)

    Ice, G.E.

    1996-01-01

    X-ray beamlines on synchrotron sources are similar in size and complexity to beamlines at state-of-the-art neutron sources. The design principles, tools, and optimization strategies for synchrotron beamlines are also similar to those of neutron beamlines. The authors describe existing design tools for modeling synchrotron radiation beamlines and describe how these tools have evolved over the last two decades. The development of increasingly powerful modeling tools has been driven by the escalating cost and sophistication of state-of-the-art beamlines and by a world-wide race to exploit advanced synchrotron radiation sources

  6. Soft x-ray beamline BL7A at the UVSOR

    International Nuclear Information System (INIS)

    Murata, T.; Matsukawa, T.; Naoe, S.; Horigome, T.; Matsudo, O.; Watanabe, M.

    1992-01-01

    A vacuum-compatible double-crystal monochromator with constant exit-beam height has been installed and operated for several years at beamline BL7A at the UVSOR facility at the Institute for Molecular Science, Okazaki, Japan, The beamline is used both for the photons from a normal bending-magnet section and those from a 4 T superconducting three-pole horizontal wiggler. Various pairs of monochromator crystals are being used with sufficient intensity and signal to noise ratio of the output signal. Basic structure of the beamline, the mechanism of the monochromator, and some typical spectra of materials with absorption edges between 850 eV and 4 keV are reported

  7. DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines.

    Science.gov (United States)

    Wojdyla, Justyna Aleksandra; Kaminski, Jakub W; Panepucci, Ezequiel; Ebner, Simon; Wang, Xiaoqiang; Gabadinho, Jose; Wang, Meitian

    2018-01-01

    Data acquisition software is an essential component of modern macromolecular crystallography (MX) beamlines, enabling efficient use of beam time at synchrotron facilities. Developed at the Paul Scherrer Institute, the DA+ data acquisition software is implemented at all three Swiss Light Source (SLS) MX beamlines. DA+ consists of distributed services and components written in Python and Java, which communicate via messaging and streaming technologies. The major components of DA+ are the user interface, acquisition engine, online processing and database. Immediate data quality feedback is achieved with distributed automatic data analysis routines. The software architecture enables exploration of the full potential of the latest instrumentation at the SLS MX beamlines, such as the SmarGon goniometer and the EIGER X 16M detector, and development of new data collection methods.

  8. G4Beamline Program for Radiation Simulations

    International Nuclear Information System (INIS)

    Beard, Kevin; Roberts, Thomas J.; Degtiarenko, Pavel

    2008-01-01

    G4beamline, a program that is an interface to the Geant4 toolkit that we have developed to simulate accelerator beamlines, is being extended with a graphical user interface to quickly and efficiently model experimental equipment and its shielding in experimental halls. The program is flexible, user friendly, and requires no programming by users, so that even complex systems can be simulated quickly. This improved user interface is of much wider application than just the shielding simulations that are the focus of this project. As an initial application, G4beamline is being extended to provide the simulations that are needed to determine the radiation sources for the proposed experiments at Jefferson Laboratory so that shielding issues can be evaluated. Since the program already has the capabilities needed to simulate the transport of all known particles, including scattering, attenuation, interactions, and decays, the extension involves implementing a user-friendly graphical user inter

  9. Automated data collection based on RoboDiff at the ESRF beamline MASSIF-1

    Energy Technology Data Exchange (ETDEWEB)

    Nurizzo, Didier, E-mail: Didier.nurizzo@esrf.fr; Guichard, Nicolas; McSweeney, Sean; Theveneau, Pascal; Guijarro, Matias; Svensson, Olof; Mueller-Dieckmann, Christoph; Leonard, Gordon [ESRF, The European Synchrotron, 71, Avenue des Martyrs,CS 40220, 38043 Grenoble (France); Bowler, Matthew W. [EMBL Grenoble Outstation, 71 Avenue des Martyrs, CS90181, 38042 Grenoble Cedex 9 (France)

    2016-07-27

    The European Synchrotron Radiation Facility has a long standing history in the automation of experiments in Macromolecular Crystallography. MASSIF-1 (Massively Automated Sample Screening and evaluation Integrated Facility), a beamline constructed as part of the ESRF Upgrade Phase I program, has been open to the external user community since July 2014 and offers a unique completely automated data collection service to both academic and industrial structural biologists.

  10. Subatomic and frontier physics with ELI Beamlines. Reality and dreams

    International Nuclear Information System (INIS)

    Drska, L.

    2010-01-01

    Complete text of publication follows. This contribution attempts to review some results of thinking about prospects for meaningful and procreative research by exploitation the potential of the unique laser technology to be available within the future ELI Beamlines Facility - an ultrashort-pulse, multi-petawatt, multi-beam, high-repetition-rate system. The presentation may be (hopefully) regarded as a specific contribution with the emphasis on two concrete areas to general ELI reports. Two sets of potential studies will be discussed: (1) Realistic experiments. (2) 'Dream' research. The first set (maybe realizable in the first phase of the laboratory work) includes the following topics: (1) Laser-driven electronuclear processes. (2) Unconventional / NLTE fusion reactions. (3) Laser positron / antimatter physics. Most detailed analysis will be presented for the subject. Some concrete themes planned for this part of the talk are: Challenges for laser positronium physics. Nuclear excitation in positron annihilation. Positrons and the laboratory astrophysics. Schemes of some experiments exploiting the ELI Beamlines possibilities will be displayed. The second ('dream') set to be outlined (under consideration as potential one for the second phase) should initiate a brainstorming discussion in these areas: (1) High-Z ion physics studies. (2) Exploring of high-gamma systems. (3) Search for hypothetic particles. Again, the highest attention will be paid to the topic. Key themes in this part: The search for hidden-sector lightweights. Challenges and opportunities in photon regeneration experiments. Potential of ELI Beamlines for the research in this area? The final section of the contribution will include some comments on technical issues related to the proposed research themes: (1) Novel targets and particle traps. (2) Diagnostics challenges and solutions. (3) Simulation / Evaluation problems. Some new approaches will be considered. Acknowledgements. This research has been

  11. ELIMED, MEDical and multidisciplinary applications at ELI-Beamlines

    International Nuclear Information System (INIS)

    Schillaci, F; Anzalone, A; Cirrone, G A P; Cuttone, G; Musumarra, A; Pisciotta, P; Romano, F; Romano, F P; Carpinelli, M; Cutroneo, M; De Martinis, C; Giove, D; Korn, G; Maggiore, M; Margarone, D; Manti, L; Perozziello, F M; Petrovic, I; Ristic-Fira, A; Renis, M

    2014-01-01

    ELI-Beamlines is one of the pillars of the pan-European project ELI (Extreme Light Infrastructure). It will be an ultra high-intensity, high repetition-rate, femtosecond laser facility whose main goal is generation and applications of high-brightness X-ray sources and accelerated charged particles in different fields. Particular care will be devoted to the potential applicability of laser-driven ion beams for medical treatments of tumors. Indeed, such kind of beams show very interesting peculiarities and, moreover, laser-driven based accelerators can really represent a competitive alternative to conventional machines since they are expected to be more compact in size and less expensive. The ELIMED project was launched thanks to a collaboration established between FZU-ASCR (ELI-Beamlines) and INFN-LNS researchers. Several European institutes have already shown a great interest in the project aiming to explore the possibility to use laser-driven ion (mostly proton) beams for several applications with a particular regard for medical ones. To reach the project goal several tasks need to be fulfilled, starting from the optimization of laser-target interaction to dosimetric studies at the irradiation point at the end of a proper designed transport beam-line. Researchers from LNS have already developed and successfully tested a high-dispersive power Thomson Parabola Spectrometer, which is the first prototype of a more performing device to be used within the ELIMED project. Also a Magnetic Selection System able to produce a small pencil beam out of a wide energy distribution of ions produced in laser-target interaction has been realized and some preliminary work for its testing and characterization is in progress. In this contribution the status of the project will be reported together with a short description of the of the features of device recently developed.

  12. End-to-End Multi-View Lipreading

    NARCIS (Netherlands)

    Petridis, Stavros; Wang, Yujiang; Li, Zuwei; Pantic, Maja

    2017-01-01

    Non-frontal lip views contain useful information which can be used to enhance the performance of frontal view lipreading. However, the vast majority of recent lipreading works, including the deep learning approaches which significantly outperform traditional approaches, have focused on frontal mouth

  13. End-to-end visual speech recognition with LSTMS

    NARCIS (Netherlands)

    Petridis, Stavros; Li, Zuwei; Pantic, Maja

    2017-01-01

    Traditional visual speech recognition systems consist of two stages, feature extraction and classification. Recently, several deep learning approaches have been presented which automatically extract features from the mouth images and aim to replace the feature extraction stage. However, research on

  14. End to End Inter-domain Quality of Service Provisioning

    DEFF Research Database (Denmark)

    Brewka, Lukasz Jerzy

    This thesis addresses selected topics of Quality of Service (QoS) provisioning in heterogeneous data networks that construct the communication environment of today's Internet. In the vast range of protocols available in different domains of network infrastructures, a few chosen ones are discussed......, the general UPnPQoS performance was assessed analytically and confirmed by simulations results. The results validate the usability of UPnP-QoS, but some open issues in the specication were identified. As a result of addressing mentioned shortcomings of UPnP-QoS, a few pre-emption algorithms for home gateway...... and discuss also access Passive Optical Network (PON) technologies, a GMPLS controlled Ten Gigabit Passive Optical Network (XGPON) was proposed. This part of the thesis introduces the possibility of managing the XG-PON by the GMPLS suite, showing again that this protocol suite is a good candidate...

  15. CMDS System Integration and IAMD End-to-End Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Cruise Missile Defense Systems (CMDS) Project Office is establishing a secure System Integration Laboratory at the AMRDEC. This lab will contain tactical Signal...

  16. End-to-End Service Oriented Architectures (SOA) Security Project

    Science.gov (United States)

    2012-02-01

    Java 6.0 (javax.ws) platform and deployed on boston.cs.purdue.edu. TB stores all data regarding sessions and services in a MySQL database, setup on...pointcut designators. JBoss AOP [JBO2] and AspectJ [ASP1] are powerful frameworks that implement AOP for Java programs. Its pointcut designators... hibernate cglib enhanced proxies <attribute name="Ignore">*$$EnhancerByCGLIB$$*</attribute> --> <attribute name="Optimized">true</attribute

  17. End-to-end experiment management in HPC

    Energy Technology Data Exchange (ETDEWEB)

    Bent, John M [Los Alamos National Laboratory; Kroiss, Ryan R [Los Alamos National Laboratory; Torrez, Alfred [Los Alamos National Laboratory; Wingate, Meghan [Los Alamos National Laboratory

    2010-01-01

    Experiment management in any domain is challenging. There is a perpetual feedback loop cycling through planning, execution, measurement, and analysis. The lifetime of a particular experiment can be limited to a single cycle although many require myriad more cycles before definite results can be obtained. Within each cycle, a large number of subexperiments may be executed in order to measure the effects of one or more independent variables. Experiment management in high performance computing (HPC) follows this general pattern but also has three unique characteristics. One, computational science applications running on large supercomputers must deal with frequent platform failures which can interrupt, perturb, or terminate running experiments. Two, these applications typically integrate in parallel using MPI as their communication medium. Three, there is typically a scheduling system (e.g. Condor, Moab, SGE, etc.) acting as a gate-keeper for the HPC resources. In this paper, we introduce LANL Experiment Management (LEM), an experimental management framework simplifying all four phases of experiment management. LEM simplifies experiment planning by allowing the user to describe their experimental goals without having to fully construct the individual parameters for each task. To simplify execution, LEM dispatches the subexperiments itself thereby freeing the user from remembering the often arcane methods for interacting with the various scheduling systems. LEM provides transducers for experiments that automatically measure and record important information about each subexperiment; these transducers can easily be extended to collect additional measurements specific to each experiment. Finally, experiment analysis is simplified by providing a general database visualization framework that allows users to quickly and easily interact with their measured data.

  18. Using SIM for strong end-to-end Application Authentication

    OpenAIRE

    Lunde, Lars; Wangensteen, Audun

    2006-01-01

    Today the Internet is mostly used for services that require low or none security. The commercial and governmental applications have started to emerge but met problems since they require strong authentication, which is both difficult and costly to realize. The SIM card used in mobile phones is a tamper resistant device that contains strong authentication mechanisms. It would be very convenient and cost-efficient if Internet services could use authentication methods based on the SIM. This mast...

  19. End-to-end simulation: The front end

    International Nuclear Information System (INIS)

    Haber, I.; Bieniosek, F.M.; Celata, C.M.; Friedman, A.; Grote, D.P.; Henestroza, E.; Vay, J.-L.; Bernal, S.; Kishek, R.A.; O'Shea, P.G.; Reiser, M.; Herrmannsfeldt, W.B.

    2002-01-01

    For the intense beams in heavy ion fusion accelerators, details of the beam distribution as it emerges from the source region can determine the beam behavior well downstream. This occurs because collective space-charge modes excited as the beam is born remain undamped for many focusing periods. Traditional studies of the source region in particle beam systems have emphasized the behavior of averaged beam characteristics, such as total current, rms beam size, or emittance, rather than the details of the full beam distribution function that are necessary to predict the excitation of these modes. Simulations of the beam in the source region and comparisons to experimental measurements at LBNL and the University of Maryland are presented to illustrate some of the complexity in beam characteristics that has been uncovered as increased attention has been devoted to developing a detailed understanding of the source region. Also discussed are methods of using the simulations to infer characteristics of the beam distribution that can be difficult to measure directly

  20. Network analysis on skype end-to-end video quality

    NARCIS (Netherlands)

    Exarchakos, Georgios; Druda, Luca; Menkovski, Vlado; Liotta, Antonio

    2015-01-01

    Purpose – This paper aims to argue on the efficiency of Quality of Service (QoS)-based adaptive streamingwith regards to perceived quality Quality of Experience (QoE). Although QoS parameters are extensivelyused even by high-end adaptive streaming algorithms, achieved QoE fails to justify their use

  1. End to End Beam Dynamics of the ESS Linac

    DEFF Research Database (Denmark)

    Thomsen, Heine Dølrath

    2012-01-01

    The European Spallation Source, ESS, uses a linear accelerator to deliver a high intensity proton beam to the target station. The nominal beam power on target will be 5 MW at an energy of 2.5 GeV. We briefly describe the individual accelerating structures and transport lines through which we have...

  2. National synchrotron light source user's manual: Guide to the VUV and x-ray beamlines: Third edition

    International Nuclear Information System (INIS)

    Gmuer, N.F.; Thomlinson, W.; White-DePace, S.

    1989-01-01

    This report contains information on the following topics: A Word on the Writing of Beamline Descriptions; Beamline Equipment Utilization for General Users; the Vacuum Ultraviolet (VUV) Storage Ring and Beamlines; VUV Beamline Descriptions--An Explanation; VUV Beamline Descriptions; X-Ray Storage Ring and Beamlines; X-Ray Beamline Descriptions--An Explanation; and X-Ray Beamline Descriptions

  3. EPICS and its role in data acquisition and beamline control

    International Nuclear Information System (INIS)

    Mooney, T. M.; Arnold, N. D.; Boucher, E.; Cha, B. K.; Goetze, K. A.; Kraimer, M. R.; Rivers, M. L.; Sluiter, R. L.; Sullivan, J. P.; Wallis, D. B.

    1999-01-01

    Beamline-control and data-acquisition software based on EPICS (a tool kit for building distributed control systems) has been running on many Advanced Photon Source beamlines for several years. EPICS itself, the collaborative software-development effort surrounding it, and EPICS-based beamline software have been described previously in general terms. This talk will review and update that material, focusing on the role EPICS core software plays in beamline applications and on the effects of a few defining characteristics of EPICS on the beamline software we have developed with it

  4. Installation of a Synchrotron Radiation Beamline Facility at the J. Bennett Johnston Sr. Center for Advanced Microstructures and Devices for the Science and Engineering Alliance. Phase I and II. Final Report

    International Nuclear Information System (INIS)

    Gooden, R.

    2000-01-01

    The Johnston Center presents a unique opportunity for scientists and engineers at southern institutions to initiate and carry out original research using synchrotron radiation ranging from visible light to hard x-rays. The Science and Engineering Alliance proposes to carry out a comprehensive new synchrotron radiation research initiative at CAMD in carefully phased steps of increasing risks. (1) materials research on existing CAMD beam lines and end stations; (2) design, construction and installation of end stations on existing CAMD beam lines, and research with this new instrumentation; (3) design, construction and operation of dedicated synchrotron radiation beam lines that covers the full spectral range of the CAMD storage ring and expanded research in the new facility

  5. Beamline Design and Instrumentation for the Imaging and Coherence Beamline I13L at the Diamond Light Source

    Science.gov (United States)

    Wagner, U. H.; Pešić, Z. D.; De Fanis, A.; Rau, C.

    2013-03-01

    I13L is a 250 m long hard x-ray beamline (6 keV to 35 keV) at the Diamond Light Source. The beamline comprises of two independent experimental endstations: one for imaging in direct space using x-ray microscopy and one for imaging in reciprocal space using coherent diffraction based imaging techniques. In this paper we will discuss the fundamental design concepts of the beamline and explain their implications for the civil engineering of the endstation building and the beamline instrumentation. For the latter this paper will focus on the beamline mirror systems and monochromators.

  6. Beamline Design and Instrumentation for the Imaging and Coherence Beamline I13L at the Diamond Light Source

    International Nuclear Information System (INIS)

    Wagner, U H; Pešić, Z D; Fanis, A De; Rau, C

    2013-01-01

    I13L is a 250 m long hard x-ray beamline (6 keV to 35 keV) at the Diamond Light Source. The beamline comprises of two independent experimental endstations: one for imaging in direct space using x-ray microscopy and one for imaging in reciprocal space using coherent diffraction based imaging techniques. In this paper we will discuss the fundamental design concepts of the beamline and explain their implications for the civil engineering of the endstation building and the beamline instrumentation. For the latter this paper will focus on the beamline mirror systems and monochromators.

  7. Shielding and activation studies for the ELI-beamlines project

    International Nuclear Information System (INIS)

    Fasso, Alberto; Korn, Georg; Versaci, Roberto; Ferrari, Anna

    2015-01-01

    ELI-beamlines is one of the four pillars of the Extreme Light Infrastructure, a European ESFRI Project, for the next generation of high-energy and high-intensity lasers. It aims at the development of high-brightness sources of X-rays and the acceleration of proton, electron, and ion beams, to be used both for pure research and practical applications. Aiming at a proper radiation protection assessment, for both shielding and activation, extensive FLUKA simulations have been performed, taking into account the laser high repetition rates. The present work, which is the continuation of the calculations presented at SATIF-10, is the first one based on the design of the facility being constructed and on the updated experimental set-up. (authors)

  8. J-PARC accelerator and neutrino beamline upgrade programme

    Science.gov (United States)

    Friend, M.

    2017-09-01

    The 30 GeV proton beam from the J-PARC Main Ring (MR) accelerator is used to produce a world-class conventional neutrino beam - the neutrino source for the J-PARC long-baseline neutrino programme, including the current T2K experiment and proposed future experiments. Planned upgrades to increase the beam power of the MR from the current ˜400 kW to the design power of 750 kW and beyond, to 1.3+ MW, are underway. These include hardware modifications, such as upgrades of the MR magnet power supplies, RF systems, and feedback systems, as well as a change of the MR beam betatron tune point. Upgrades to the neutrino beamline, such as to the proton beam monitoring, horns, and radioactive material handling, will also be required to accommodate the increased proton beam power. An overview of planned J-PARC MR and neutrino facility upgrades is given.

  9. Design and development of PEEM/ARPES beamline for Indus-2 synchrotron radiation source

    International Nuclear Information System (INIS)

    Goutam, U.K.; Sharma, R.K.; Jagannath; Gadkari, S.C.; Yakhmi, J.V.; Sahni, V.C.

    2008-06-01

    A high resolution beamline having two branches dedicated to Photo Emission Electron Microscopy (PEEM) and Angle Resolved Photo Electron Spectroscopy (ARPES) is planned for Indus-2 synchrotron radiation source. These two techniques open a wide field of new applications in materials research and have proven to be powerful tools to investigate topological, elemental, chemical state, electronic and magnetic properties of surfaces, thin films, and multilayers at high resolutions.The beamline will cover a large energy range from 10 to 4000 eV and is expected to deliver a flux of the order of ∼10 13 ph/s/0.1%B.W. with an energy resolution of ∼10 -4 . This report describes the optical design, beamline layout, effects of heat load on various components and the expected performance of the beamline. This beamline would have a collimating mirror for vertical collimation of the beam, plane grating/double crystal monochromator to make the white synchrotron beam monochromatic in entire energy range, toroidal mirror for splitting the beam as well as for intermediate focusing and a Kirkpatrick-Baez (K-B) mirror system for focusing the beam both in vertical and horizontal directions at the final sample location. Total beamline will be 36m long. Optical design has been carried out involving various computer codes such as XOP2.1, SHADOWVUI, SPECTRA 8.0 etc. Head load calculations have been performed using ANSYS, a finite element analysis code. Using this code, temperature distribution, thermal deformation and slope error values for collimating mirror, grating monochromator and double crystal monochromator using several possible cooling arrangements have been calculated and depending on these parameters, best options for different components have been selected for the beamline. Experimental stations of this beamline consist of ultra-high vacuum compatible chambers in which various probes, analyzers, detectors and other facilities are housed. A toroidal electron energy analyzer will

  10. The quality assessment of radial and tangential neutron radiography beamlines of TRR

    International Nuclear Information System (INIS)

    Dastjerdi, M.H. Choopan; Movafeghi, A.; Khalafi, H.; Kasesaz, Y.

    2017-01-01

    To achieve a quality neutron radiographic image in a relatively short exposure time, the neutron radiography beam must be of good quality and relatively high neutron flux. Characterization of a neutron radiography beam, such as determination of the image quality and the neutron flux, is vital for producing quality radiographic images and also provides a means to compare the quality of different neutron radiography facilities. This paper provides a characterization of the radial and tangential neutron radiography beamlines at the Tehran research reactor. This work includes determination of the facilities category according to the American Society for Testing and Materials (ASTM) standards, and also uses the gold foils to determine the neutron beam flux. The radial neutron beam is a Category I neutron radiography facility, the highest possible quality level according to the ASTM. The tangential beam is a Category IV neutron radiography facility. Gold foil activation experiments show that the measured neutron flux for radial beamline with length-to-diameter ratio (L/D) =150 is 6.1× 10 6 n cm −2 s −1 and for tangential beamline with (L/D)=115 is 2.4× 10 4 n cm −2 s −1 .

  11. G4beamline Simulations for H8

    CERN Document Server

    Thoresen, Freja

    2015-01-01

    Detailed simulations of the H8 beam line at the North Area, using the G4beamline software were performed in the framework of this study. The conventions used by the program are analysed. Having modelled precisely the beam line, several studies examining the beam transmission and composition were performed. The results were compared with measurements, where a satisfactory agreement was found. The muon production and transport is studied in details throughout the beam line.

  12. Muon Colliders: the Ultimate Neutrino Beamlines

    International Nuclear Information System (INIS)

    King, Bruce J.

    1999-01-01

    It is shown that muon decays in straight sections of muon collider rings will naturally produce highly collimated neutrino beams that can be several orders of magnitude stronger than the beams at existing accelerators. We discuss possible experimental setups and give a very brief overview of the physics potential from such beamlines. Formulae are given for the neutrino event rates at both short and long baseline neutrino experiments in these beams

  13. Nomenclature of SLC Arc beamline components

    International Nuclear Information System (INIS)

    Silva, J.; Weng, W.T.

    1986-01-01

    This note defines I and C formal names for beamline components in the Arc as specified in the TRANSPORT decks ARCN FINAL and ARCS FINAL of June 5, 1985. The formal name consists of three fields: the primary name, the zone and the unit number. The general principles and guidelines are explained in Reference 1. The rationale and the final resolutions of the naming conventions for the Arc are explained

  14. CERN’s 2016 Beamline for Schools competition starts on 17 November

    CERN Document Server

    2015-01-01

    Spread the word: CERN is offering high-school students from around the world the chance to create and perform a scientific experiment on a CERN accelerator beamline. What better way to learn about physics?    (Video: Noemi Caraban​/CERN ) Now in its third year, the Beamline for Schools competition is open to teams of at least five students aged 16 and with at least one adult supervisor or “coach”. Students can find out about the beamline and facilities via http://cern.ch/bl4s, then think of a simple, creative experiment. They can register their team from 17 November to start receiving e-mail updates. They then submit a written proposal and a short video by 31 March 2016. The winners will be announced in June and will come to CERN, preferably in September 2016. Previous winners have tested webcams and classroom-grown crystals at the beamline, others have studied how particles decay and investigated high-energy gamma rays. All participants will receive...

  15. The current status of small-angle x-ray scattering beamline at Diamond Light Source

    International Nuclear Information System (INIS)

    Inoue, Katsuaki; Doutch, James; Terrill, Nick

    2013-01-01

    The small-angle X-ray scattering (SAXS) covers the major disciplines of biology, chemistry and physics delivering structural and dynamic information in nanoscience, mesoscopic architectures, supramolecular structures, and nucleation/growth of crystals. SAXS is also proving to be important in archaeological, environmental, and conservation sciences, and has further indicated its ability to span wide-ranging scientific disciplines. Thus, strong needs for SAXS studies are increasing significantly in a broad range of scientific fields year by year. Based on such a background, the demand for high throughput SAXS experiments is increasing. At the synchrotron facility, Diamond Light Source, one SAXS beamline, Non-crystalline diffraction I22 is now operational and highly automated throughput small-angle X-ray scattering (HATSAXS) beamline B21 is now under construction. I22 is the Undulator beamline and wide varieties of experiments, including time-resolved experiments are attempted. Based on the concept of HATSAXS, the key feature of B21 will focuses on the automation of end-station equipment. A automated sample changer has been purchased for solution SAXS measurements on biomolecules. A robotic-arm-type automated sample changer that is capable of handling several kinds of samples in material science is also being constructed. B21 is expected to successfully provide all users highly automated throughput measurements with the highest possible reliability and accuracy. Construction of this beamline will end in the second half of 2012, and will be open for users in the early summer of 2013 after commissioning. (author)

  16. The materials science synchrotron beamline EDDI for energy-dispersive diffraction analysis

    International Nuclear Information System (INIS)

    Genzel, Ch.; Denks, I.A.; Gibmeier, J.; Klaus, M.; Wagener, G.

    2007-01-01

    In April 2005 the materials science beamline EDDI (Energy Dispersive DIffraction) at the Berlin synchrotron storage ring BESSY started operation. The beamline is operated in the energy-dispersive mode of diffraction using the high energy white photon beam provided by a superconducting 7 T multipole wiggler. Starting from basic information on the beamline set-up, its measuring facilities and data processing concept, the wide range of applications for energy-dispersive diffraction is demonstrated by a series of examples coming from different fields in materials sciences. It will be shown, that the EDDI beamline is especially suitable for the investigation of structural properties and gradients in the near surface region of polycrystalline materials. In particular, this concerns the analysis of multiaxial residual stress fields in the highly stressed surface zone of technical parts. The high photon flux further facilitates fast in situ experiments at room as well as high temperature to monitor for example the growth kinetics and reaction in thin film growth

  17. Current status of the hard x-ray nanoprobe beamline at the SSRF

    Science.gov (United States)

    Li, Aiguo; Jiang, Hui; Wang, Hua; Zhang, Zhaohong; He, Yan; Zhao, Gaofeng; Shu, Deming

    2017-09-01

    The hard X-ray nanoprobe beamline (HXN) designed at the Shanghai Synchrotron Radiation facility (SSRF) will be of capability to realize a focal spot size of 10 nm for hard X-rays to satisfy requirements in biology, environmental, material sciences and etc.. The beamline includes two modes of operation, high energy resolution mode and high flux mode respectively. High flux mode utilizes the multilayer KB system to obtain high-flux diffraction-limited focusing of 10nm. An ultra-high-precision figure fabrication for diffraction-limited focusing is required to meet the Rayleigh Criterion. An idea to overcome this problem is to introduce a phase compensator upstream of the KB system to compensate the wavefront errors in the beamline. At wavelength speckle-based method will be used to measure the wavefront error in the beamline and feedback to the phase compensator. Vibration measurements have been carried out at the secondary source and endstation hutch. The flexure hinge mechanisms and high-precision actuators ensure the KB system and sample manipulator working with high stability. The building of HXN has been designed and is under construction at present.

  18. Upgrade of the Proton West secondary beamline

    International Nuclear Information System (INIS)

    Spiegel, L.

    1989-01-01

    As originally designed and operated, protons entering PW6 were steered by a series of EPB dipoles into a single interaction length beryllium target, some 43 feet from the enclosure wall. Ensuing secondary beams, either p + /π + or p - /π - , were collected by a string of quadrupoles following the target, steered westward, away from the Proton Center line, through PW6 and PW7, and ultimately focussed on experiment production targets located within the large PW8 hall. Around the Spring of 1988 it was decided to upgrade the existing Proton West secondary beamline to allow for transport of a primary proton beam, anticipated to be either 800 or 900 GeV/c, through PW8. This upgrade project, which is now nearing completion, was largely motivated by the then recent approval of E-771, a hadronic beauty production experiment located in PW8. E-771 represents the third in a series of experiments for the large-acceptance dimuon spectrometer presently located at the end of the Proton West beamline. This Technical Memo is a summary of the upgrade --- an explanation of the underlying strategy and a documentation of the final locations of the secondary beamline elements. 6 refs., 2 figs., 2 tabs

  19. The development of harmonic rejection mirror on XAFS beamline at SSRF

    International Nuclear Information System (INIS)

    Fu Yuan; Xue Song; Wei Xiangjun; Jiang Zheng; Gu Songqi; Chen Ming; Huang Yuying; Yu Xiaohan

    2009-01-01

    This article discusses the development of harmonic rejection mirror (HRM) on the XAFS beamline at Shanghai Synchrotron Radiation Facility (SSRF). The HRM can apply pure spectrum for XAFS experiment. The HRM mechanism includes mirror holding system, horizontal switch system and three-points adjustment system. We make analysis and calculation in mechanism design. At last we evaluate the HRM capability based on the rocking curve got in test. (authors)

  20. Status of Indus-1 and Indus-2 beamlines

    CERN Document Server

    Nandedkar, R V

    2003-01-01

    Indus-1 and Indus-2 are two synchrotron radiation sources that are planned in India. Indus-1 is a 450 MeV electron storage ring for vacuum ultra-violet soft X-ray radiation. This source is operational. Two beamlines, viz. a soft X-ray/vacuum ultra-violet reflectometry beamline and an angle integrated photoelectron spectroscopy beamline are already operational. Angle resolved photoelectron spectroscopy and photophysics beamlines are going to be operational soon. The second Indian synchrotron source is the 2.5 GeV Indus-2 electron storage ring that is under construction and is expected to be ready for commissioning in the year 2003. Of the total 27 beamlines possible on this ring, about 10 beamlines are already planned and are in the design stage.

  1. Status of Indus-1 and Indus-2 beamlines

    International Nuclear Information System (INIS)

    Nandedkar, R.V.; Sawhney, K.J.S.

    2003-01-01

    Indus-1 and Indus-2 are two synchrotron radiation sources that are planned in India. Indus-1 is a 450 MeV electron storage ring for vacuum ultra-violet soft X-ray radiation. This source is operational. Two beamlines, viz. a soft X-ray/vacuum ultra-violet reflectometry beamline and an angle integrated photoelectron spectroscopy beamline are already operational. Angle resolved photoelectron spectroscopy and photophysics beamlines are going to be operational soon. The second Indian synchrotron source is the 2.5 GeV Indus-2 electron storage ring that is under construction and is expected to be ready for commissioning in the year 2003. Of the total 27 beamlines possible on this ring, about 10 beamlines are already planned and are in the design stage

  2. Rotary Valve & Beamline Highlights for Fiscal Year 2017

    Energy Technology Data Exchange (ETDEWEB)

    Fitsos, P [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-09-21

    This Fiscal Year (FY) work was divided between continued testing and characterization work of the Rotary Valve (RV) and mechanical engineering support for the beamline hardware stands. This configuration is more like the final setup with the accelerator firing deuterons down the evacuated beamline toward the RV for interaction with the deuterium and neutron production. The beamline cells were part of an experiment to reduce the impact that RV gas would have on the beamline vacuum. This work will be reported separately from this report. Previous testing had been with the beamline at atmospheric pressure and now the goal was to get test results of the RV with it connected to a beamline that’s running at some level of vacuum.

  3. Computer control of the ISX-B neutral injection beamlines

    International Nuclear Information System (INIS)

    Hanna, P.C.

    1982-09-01

    A system of controls for the Impurity Study Experiment (ISX-B) neutral injection beamlines at the Oak Ridge National Laboratory is presented. The system uses standard CAMAC equipment interfaced to the actual beamline controls and driven by a PDP-11/34 mini-computer. It is designed to relieve the operator of most of the mundane tasks of beam injection and also to reduce the number of operators needed to monitor multiple beamlines

  4. Development of the XFP beamline for x-ray footprinting at NSLS-II

    Energy Technology Data Exchange (ETDEWEB)

    Bohon, Jen, E-mail: jbohon@bnl.gov; Sullivan, Michael; Abel, Don; Toomey, John; Chance, Mark R., E-mail: mark.chance@case.edu [Case Center for Synchrotron Biosciences, Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH (United States); Dvorak, Joseph [Brookhaven National Laboratory, Upton, NY (United States)

    2016-07-27

    For over a decade, synchrotron-based footprinting studies at the NSLS X28C beamline have provided unique insights and approaches for examining the solution-state structures of large macromolecular assemblies, membrane proteins, and soluble proteins, for time-resolved studies of macromolecular dynamics, and most recently for in vivo studies of RNA-protein complexes. The transition from NSLS to NSLS-II has provided the opportunity to create an upgraded facility for the study of increasingly complex systems; progress on the development of the XFP (X-ray Footprinting for In Vitro and In Vivo Structural Studies of Biological Macromolecules) beamline at NSLS-II is presented here. The XFP beamline will utilize a focused 3-pole wiggler source to deliver a high flux density x-ray beam, where dynamics can be studied on the microsecond to millisecond timescales appropriate for probing biological macromolecules while minimizing sample perturbation. The beamline optics and diagnostics enable adaptation of the beam size and shape to accommodate a variety of sample morphologies with accurate measurement of the incident beam, and the upgrades in sample handling and environment control will allow study of highly sensitive or unstable samples. The XFP beamline is expected to enhance relevant flux densities more than an order of magnitude from that previously available at X28C, allowing static and time-resolved structural analysis of highly complex samples that have previously pushed the boundaries of x-ray footprinting technology. XFP, located at NSLS-II 17-BM, is anticipated to become available for users in 2016.

  5. 7-GeV advanced photon source beamline initiative: Conceptual design report

    International Nuclear Information System (INIS)

    1993-05-01

    The DOE is building a new generation 6-7 GeV Synchrotron Radiation Source known as the Advanced Photon Source (APS) at Argonne National Laboratory. This facility, to be completed in FY 1996, can provide 70 x-ray sources of unprecedented brightness to meet the research needs of virtually all scientific disciplines and numerous technologies. The technological research capability of the APS in the areas of energy, communications and health will enable a new partnership between the DOE and US industry. Current funding for the APS will complete the current phase of construction so that scientists can begin their applications in FY 1996. Comprehensive utilization of the unique properties of APS beams will enable cutting-edge research not currently possible. It is now appropriate to plan to construct additional radiation sources and beamline standard components to meet the excess demands of the APS users. In this APS Beamline Initiative, 2.5-m-long insertion-device x-ray sources will be built on four straight sections of the APS storage ring, and an additional four bending-magnet sources will also be put in use. The front ends for these eight x-ray sources will be built to contain and safeguard access to these bright x-ray beams. In addition, funds will be provided to build standard beamline components to meet scientific and technological research demands of the Collaborative Access Teams. The Conceptual Design Report (CDR) for the APS Beamline Initiative describes the scope of all the above technical and conventional construction and provides a detailed cost and schedule for these activities. The document also describes the preconstruction R ampersand D plans for the Beamline Initiative activities and provides the cost estimates for the required R ampersand D

  6. Rossendorf Beamline at ESRF (ROBL-CRG). Bi-annual report 2009/2010

    International Nuclear Information System (INIS)

    Scheinost, Andreas C.; Baehtz, Carsten

    2011-01-01

    The Rossendorf Beamline (ROBL) - located at BM20 of the European Synchrotron Radiation Facility (ESRF) in Grenoble, France - is in operation since 1998. This 7th report covers the period from January 2009 to December 2010. In these two years, 67 peer- reviewed papers have been published based on experiments done at the beamline, more than in any biannual period before. Six highlight reports have been selected for this report to demonstrate the scientific strength and diversity of the experiments performed on the two end-stations of the beamline, dedicated to Radiochemistry (RCH) and Materials Research (MRH). The beamtime was more heavily overbooked than ever before, with an acceptance rate of only 25% experiments. We would like to thank our external proposal review members, Prof. Andre Maes (KU Leuven, Belgium), Prof. Laurent Charlet (UJF Grenoble, France), Dr. Andreas Leinweber (MPI Metallforschung, Stuttgart, Germany), Prof. David Rafaja (TU Bergakademie Freiberg, Germany), Prof. Dirk Meyer (TU Dresden, Germany), who evaluated the inhouse proposals in a thorough manner, thereby ensuring that beamtime was distributed according to scientific merit. The period was not only characterized by very successful science, but also by intense work on the optics upgrade. In spring 2009, a workshop was held at ROBL, assembling beamline experts from German, Spanish and Swiss synchrotrons, to evaluate the best setup for the new optics. These suggestions was used to prepare the call for tender published in July 2009. From the tender acceptance in November 2009 on, a series of design review meetings and factory acceptance tests followed. Already in July 2010, the first piece of equipment was delivered, the new double-crystal, double-multilayer monochromator. The disassembly of the old optics components started end of July, 2011, followed by the installation of the new components. As of December 2011, the new optics have seen the first test beam and thorough hot commissioning will

  7. Rossendorf Beamline at ESRF (ROBL-CRG). Bi-annual report 2009/2010

    Energy Technology Data Exchange (ETDEWEB)

    Scheinost, Andreas C; Baehtz, Carsten [eds.

    2011-07-01

    The Rossendorf Beamline (ROBL) - located at BM20 of the European Synchrotron Radiation Facility (ESRF) in Grenoble, France - is in operation since 1998. This 7th report covers the period from January 2009 to December 2010. In these two years, 67 peer- reviewed papers have been published based on experiments done at the beamline, more than in any biannual period before. Six highlight reports have been selected for this report to demonstrate the scientific strength and diversity of the experiments performed on the two end-stations of the beamline, dedicated to Radiochemistry (RCH) and Materials Research (MRH). The beamtime was more heavily overbooked than ever before, with an acceptance rate of only 25% experiments. We would like to thank our external proposal review members, Prof. Andre Maes (KU Leuven, Belgium), Prof. Laurent Charlet (UJF Grenoble, France), Dr. Andreas Leinweber (MPI Metallforschung, Stuttgart, Germany), Prof. David Rafaja (TU Bergakademie Freiberg, Germany), Prof. Dirk Meyer (TU Dresden, Germany), who evaluated the inhouse proposals in a thorough manner, thereby ensuring that beamtime was distributed according to scientific merit. The period was not only characterized by very successful science, but also by intense work on the optics upgrade. In spring 2009, a workshop was held at ROBL, assembling beamline experts from German, Spanish and Swiss synchrotrons, to evaluate the best setup for the new optics. These suggestions was used to prepare the call for tender published in July 2009. From the tender acceptance in November 2009 on, a series of design review meetings and factory acceptance tests followed. Already in July 2010, the first piece of equipment was delivered, the new double-crystal, double-multilayer monochromator. The disassembly of the old optics components started end of July, 2011, followed by the installation of the new components. As of December 2011, the new optics have seen the first test beam and thorough hot commissioning will

  8. Functional description of APS beamline front ends

    International Nuclear Information System (INIS)

    Kuzay, T.

    1993-02-01

    Traditional synchrotron sources were designed to produce bending magnet radiation and have proven to be an essential scientific tool. Currently, a new generation of synchrotron sources is being built that will be able to accommodate a large number of insertion device (ID) and high quality bending magnet (BM) sources. One example is the 7-GeV Advanced Photon Source (APS) now under construction at Argonne National Laboratory. The research and development effort at the APS is designed to fully develop the potential of this new generation of synchrotron sources. Of the 40 straight sections in the APS storage ring, 34 will be available for IDs. The remaining six sections are reserved for the storage ring hardware and diagnostics. Although the ring incorporates 80 BMs, only 40 of them can be used to extract radiation. The accelerator hardware shadows five of these 40 bending magnets, so the maximum number of BM sources on the lattice is 35. Generally, a photon beamline consists of four functional sections. The first section is the ID or the BM, which provides the radiation source. The second section, which is immediately outside the storage ring but inside a concrete shielding tunnel, is the front end, which is designed to control, define, and/or confine the x-ray beam. In the case of the APS, the front ends are designed to confine the photon beam. The third section, just outside the concrete shielding tunnel and on the experimental floor, is the first optics enclosure, which contains optics to filter and monochromatize the photon beam. The fourth section of a beamline consists of beam transports, additional optics, and experiment stations to do the scientific investigations. This document describes only the front ends of the APS beamlines

  9. SUNY beamline facilities at the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Coppens, P.

    1993-01-01

    This document presents information concerning: crystallography (single crystal studies); crystallography (powder diffraction); crystallography (surface structure); exafs and interface studies; and small angle scattering

  10. [SUNY beamline facilities at the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Coppens, P.

    1992-01-01

    This report contains short discussions on the following topics which mainly deal with superconductors: crystallography; surface structure; scattering and EXAFS studies; small angle scattering of x-rays

  11. (SUNY beamline facilities at the National Synchrotron Light Source)

    Energy Technology Data Exchange (ETDEWEB)

    Coppens, P.

    1992-01-01

    This report contains short discussions on the following topics which mainly deal with superconductors: crystallography; surface structure; scattering and EXAFS studies; small angle scattering of x-rays. (LSP)

  12. BSRF-3B3 Medium Energy X-ray Beamline and Its Application for XAFS Research

    International Nuclear Information System (INIS)

    Ma Chenyan; Cui Mingqi; Zhou Kejin; Zhao Yidong; Tian Yulian; Wu Ziyu; Zheng Lei; Zhu Jie; Zhao Jia; Chen Kai; Sun Lijuan

    2007-01-01

    A new medium X-ray beamline 3B3 covering energy from 1.2 keV up to 6.0 keV was built at Beijing Synchrotron Radiation Facility (BSRF) in 2005. With perfect capability of high monochromaticity, good focus and low harmonics, it could be applied to study metrology, optic component characteristics and medium X-ray absorption spectroscopy (XAS). A simple XAFS apparatus has been set up and some measurements such as S, P, Cl, Ca, Al, Mg K-edge X-ray absorption fine structure (XAFS) in their compounds have also been carried out. The results show that it is feasible to do XAFS research at 3B3 beamline under present condition. The fabrication of a more delicate medium XAFS spectrometer is underway including transmission, fluorescence and electronic yield modes

  13. Calibration and standards beamline 6.3.2 at the ALS

    International Nuclear Information System (INIS)

    Underwood, J.H.; Gullikson, E.M.; Koike, M.

    1997-01-01

    More sophisticated optics for the x-ray, soft x-ray and far ultraviolet spectral regions being developed for synchrotron radiation research and many other applications, require accurate calibration and standards facilities for measuring reflectivity of mirrors and multilayer coatings, transmission of thin films, bandpass of multilayers, efficiency of gratings or detectors, etc. For this purpose beamline 6.3.2 was built at the ALS. Its energy coverage, versatility, simplicity and convenience also make it useful for a wide range of other experiments. The paper describes the components of this beamline, consisting of: a four jaw aperture; a horizontal focusing mirror; a monochromator; exit slit; vertical focusing mirror; mechanical and vacuum system; reflectometer; filter wheels; and data acquisition system

  14. Surveying and optical tooling technologies combined to align a skewed beamline at the LAMPF accelerator

    International Nuclear Information System (INIS)

    Bauke, W.; Clark, D.A.; Trujillo, P.B.

    1985-01-01

    Optical Tooling evolved from traditional surveying, and both technologies are sometimes used interchangeably in large industrial installations, since the instruments and their specialized adapters and supports complement each other well. A unique marriage of both technologies was accomplished in a novel application at LAMPF, the Los Alamos Meson Physics Facility. LAMPF consists of a linear accelerator with multiple target systems, one of which had to be altered to accommodate a new beamline for a neutrino experiment. The new line was to be installed into a crowded beam tunnel and had to be skewed and tilted in compound angles to avoid existing equipment. In this paper we describe how Optical Tooling was used in conjunction with simple alignment and reference fixtures to set fiducials on the magnets and other mechanical components of the beamline, and how theodolites and sight levels were then adapted to align these components along the calculated skew planes. Design tolerances are compared with measured alignment results

  15. Calibration and standards beamline 6.3.2 at the ALS

    Energy Technology Data Exchange (ETDEWEB)

    Underwood, J.H.; Gullikson, E.M.; Koike, M. [Ernest Orlando Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    More sophisticated optics for the x-ray, soft x-ray and far ultraviolet spectral regions being developed for synchrotron radiation research and many other applications, require accurate calibration and standards facilities for measuring reflectivity of mirrors and multilayer coatings, transmission of thin films, bandpass of multilayers, efficiency of gratings or detectors, etc. For this purpose beamline 6.3.2 was built at the ALS. Its energy coverage, versatility, simplicity and convenience also make it useful for a wide range of other experiments. The paper describes the components of this beamline, consisting of: a four jaw aperture; a horizontal focusing mirror; a monochromator; exit slit; vertical focusing mirror; mechanical and vacuum system; reflectometer; filter wheels; and data acquisition system.

  16. A Superbend X-Ray Microdiffraction Beamline at the Advanced Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Tamura, N.; Kunz, M.; Chen, K.; Celestre, R.S.; MacDowell, A.A.; Warwick, T.

    2009-03-10

    Beamline 12.3.2 at the Advanced Light Source is a newly commissioned beamline dedicated to x-ray microdiffraction. It operates in both monochromatic and polychromatic radiation mode. The facility uses a superconducting bending magnet source to deliver an X-ray spectrum ranging from 5 to 22 keV. The beam is focused down to {approx} 1 um size at the sample position using a pair of elliptically bent Kirkpatrick-Baez mirrors enclosed in a vacuum box. The sample placed on high precision stages can be raster-scanned under the microbeam while a diffraction pattern is taken at each step. The arrays of diffraction patterns are then analyzed to derive distribution maps of phases, strain/stress and/or plastic deformation inside the sample.

  17. Diagnostics Beamline for the SRF Gun Project

    CERN Document Server

    Kamps, T; Goldammer, K; Krämer, Dietrich; Kuske, P; Kuszynski, J; Lipka, D; Marhauser, F; Quast, T; Richter, R

    2005-01-01

    A superconducting rf photo electron injector (SRF gun) is currently under construction by a collaboration between BESSY, DESY, FZR and MBI. The project aims at the design and setup of an CW SRF gun including a diagnostics beamline for the ELBE FEL and to address R&D issues on low emittance injectors for future light sources such as the BESSY FEL. Of critical importance for the injector performance is the control of the electron beam parameters. For this reason a compact diagnostics beamline is under development serving a multitude of operation settings ranging from low-charge (77pC), low-emittance (1 pi mm mrad) mode to high-charge (2.5nC) operation of the gun. For these operation modes beam dynamics simulations are resulting in boundary conditions for the beam instrumentation. Proven and mature technology is projected wherever possible, for example for current and beam position monitoring. The layout of the beam profile and emittance measurement systems is described. For the bunch length, which varies be...

  18. Automation in structural biology beamlines of the Photon Factory

    International Nuclear Information System (INIS)

    Igarashi, Noriyuki; Hiraki, Masahiko; Matsugaki, Naohiro; Yamada, Yusuke; Wakatsuki, Soichi

    2007-01-01

    The Photon Factory currently operates four synchrotron beamlines for protein crystallography and two more beamlines are scheduled to be constructed in the next years. Over the last years these beamlines have been upgraded and equipped with a fully automated beamline control system based on a robotic sample changer. The current system allows for remote operation, controlled from the user's area, of sample mounting, centering and data collection of pre-frozen crystals mounted in Hampton-type cryo-loops on goniometer head. New intuitive graphical user interfaces have been developed so as to control the complete beamline operation. Furthermore, algorithms for automatic sample centering based on pattern matching and X-ray beam scanning are being developed and combined with newly developed diffraction evaluation programs in order to complete entire automation of the data collection. (author)

  19. Generic radiation safety design for SSRL synchrotron radiation beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Liu, James C. [Radiation Protection Department, Stanford Linear Accelerator Center (SLAC), MS 48, P.O. Box 20450, Stanford, CA 94309 (United States)]. E-mail: james@slac.stanford.edu; Fasso, Alberto [Radiation Protection Department, Stanford Linear Accelerator Center (SLAC), MS 48, P.O. Box 20450, Stanford, CA 94309 (United States); Khater, Hesham [Radiation Protection Department, Stanford Linear Accelerator Center (SLAC), MS 48, P.O. Box 20450, Stanford, CA 94309 (United States); Prinz, Alyssa [Radiation Protection Department, Stanford Linear Accelerator Center (SLAC), MS 48, P.O. Box 20450, Stanford, CA 94309 (United States); Rokni, Sayed [Radiation Protection Department, Stanford Linear Accelerator Center (SLAC), MS 48, P.O. Box 20450, Stanford, CA 94309 (United States)

    2006-12-15

    To allow for a conservative, simple, uniform, consistent, efficient radiation safety design for all SSRL beamlines, a generic approach has been developed, considering both synchrotron radiation (SR) and gas bremsstrahlung (GB) hazards. To develop the methodology and rules needed for generic beamline design, analytic models, the STAC8 code, and the FLUKA Monte Carlo code were used to pre-calculate sets of curves and tables that can be looked up for each beamline safety design. Conservative beam parameters and standard targets and geometries were used in the calculations. This paper presents the SPEAR3 beamline parameters that were considered in the design, the safety design considerations, and the main pre-calculated results that are needed for generic shielding design. In the end, the rules and practices for generic SSRL beamline design are summarized.

  20. An ultrahigh vacuum monochromator for photophysics beamline

    International Nuclear Information System (INIS)

    Meenakshi Raja Rao, P.; Padmanabhan, Saraswathy; Raja Sekhar, B.N.; Shastri, Aparna; Khan, H.A.; Sinha, A.K.

    2000-08-01

    The photophysics beamline designed for carrying out photoabsorption and fluorescence studies using the 450 MeV Synchrotron Radiation Source (SRS), INDUS-1, uses a 1 metre monochromator as premonochromator for monochromatising the continuum. An ultra high vacuum compatible monochromator in Seya-Namioka mount has been designed and fabricated indigenously. The monochromator was assembled and tested for its performance. Wavelength scanning mechanism was tested for its reproducibility and the monochromator was tested for its resolution using UV and VUV sources. An average spectral resolution of 2.5 A was achieved using a 1200 gr/mm grating. A wavelength repeatability of ± 1A was obtained. An ultra high vacuum of 2 X 10 -8 mbar was also achieved in the monochromator. Details of fabrication, assembly and testing are presented in this report. (author)

  1. Mirrors for synchrotron-radiation beamlines

    International Nuclear Information System (INIS)

    Howells, M.R.

    1993-09-01

    The authors consider the role of mirrors in synchrotron-radiation beamlines and discuss the optical considerations involved in their design. They discuss toroidal, spherical, elliptical, and paraboloidal mirrors in detail with particular attention to their aberration properties. They give a treatment of the sine condition and describe its role in correcting the coma of axisymmetric systems. They show in detail how coma is inevitable in single-reflection, grazing-incidence systems but correctable in two-reflection systems such as those of the Wolter type. In an appendix, they give the theory of point aberrations of reflectors of a general shape and discuss the question of correct naming of aberrations. In particular, a strict definition of coma is required if attempts at correction are to be based on the sine condition

  2. MX: A beamline control system toolkit

    Science.gov (United States)

    Lavender, William M.

    2000-06-01

    The development of experimental and beamline control systems for two Collaborative Access Teams at the Advanced Photon Source has resulted in the creation of a portable data acquisition and control toolkit called MX. MX consists of a set of servers, application programs and libraries that enable the creation of command line and graphical user interface applications that may be easily retargeted to new and different kinds of motor and device controllers. The source code for MX is written in ANSI C and Tcl/Tk with interprocess communication via TCP/IP. MX is available for several versions of Unix, Windows 95/98/NT and DOS. It may be downloaded from the web site http://www.imca.aps.anl.gov/mx/.

  3. Quantitative SRXRF analysis on the BL15U1 beamline at SSRF

    International Nuclear Information System (INIS)

    Zhang Yanle; Yu Xiaohan

    2010-01-01

    In this paper, we give an introduction first to two quantification methods for synchrotron radiation X-ray fluorescence analysis (SRXRF), namely fundamental parameters method and Monte-Carlo simulation method, for their application on the BL15U1 beamline (hard X-ray microprobe) at SSRF (Shanghai Synchrotron Radiation Facility). Effectiveness of the two methods is demonstrated and the XRF detection limits of the BL15U1 beamline are calculated. The results show that, quantitative analysis at the ppm level can be done using the two methods, with an accuracy of better than 10%. Although both the methods are valid for the SRXRF data analysis,the Monte Carlo method gives better analysis result, as it compares the simulated spectrum with the experiment spectrum, and this helps the determination of experiment parameters and thus minimizes the error caused by incorrect parameters. Finally, the detection limits shows that the BL15U1 beamline is capable of carrying out standard-of-the-art XRF experiment. (authors)

  4. Optimization of a general-purpose, actively scanned proton beamline for ocular treatments: Geant4 simulations.

    Science.gov (United States)

    Piersimoni, Pierluigi; Rimoldi, Adele; Riccardi, Cristina; Pirola, Michele; Molinelli, Silvia; Ciocca, Mario

    2015-03-08

    The Italian National Center for Hadrontherapy (CNAO, Centro Nazionale di Adroterapia Oncologica), a synchrotron-based hospital facility, started the treatment of patients within selected clinical trials in late 2011 and 2012 with actively scanned proton and carbon ion beams, respectively. The activation of a new clinical protocol for the irradiation of uveal melanoma using the existing general-purpose proton beamline is foreseen for late 2014. Beam characteristics and patient treatment setup need to be tuned to meet the specific requirements for such a type of treatment technique. The aim of this study is to optimize the CNAO transport beamline by adding passive components and minimizing air gap to achieve the optimal conditions for ocular tumor irradiation. The CNAO setup with the active and passive components along the transport beamline, as well as a human eye-modeled detector also including a realistic target volume, were simulated using the Monte Carlo Geant4 toolkit. The strong reduction of the air gap between the nozzle and patient skin, as well as the insertion of a range shifter plus a patient-specific brass collimator at a short distance from the eye, were found to be effective tools to be implemented. In perspective, this simulation toolkit could also be used as a benchmark for future developments and testing purposes on commercial treatment planning systems.

  5. Opening of material analysis beamline (BL-5) at NewSUBARU for industrial enterprises

    International Nuclear Information System (INIS)

    Hasegawa, Takayuki; Uemura, Masaharu; Tsurui, Takafumi; Shimizu, Masayoshi; Amemiya, Kenta; Fukushima, Sei; Ohta, Toshiaki; Motoyama, Muneyuki; Kanda, Kazuhiro

    2010-01-01

    A material analysis beamline for the industrial enterprises' use was completed at BL-5 of NewSUBARU synchrotron radiation facility in University of Hyogo in March 2008. BL-5 consists of two branch lines, one is a double crystal monochromator beamline (BL-5A) for the use in the higher-energy region (1300-4000 eV) and the other is a varied line spacing plane grating (VLSPG) monochromator beamline (BL-5B) for the use in the lower-energy region (50-1300 eV). These two branch lines can be operated simultaneously. BL-5 covers the soft X-ray region from 50 to 4000 eV and X-ray absorption spectrum can be measured with a high-energy resolution. The XAFS measurements in the total electron yield (TEY) and fluorescence yield (FLY) can be performed at BL-5A and BL-5B. In addition, the XPS spectra can be measured at BL-5B. BL-5 will be managed and maintained by the Synchrotron Analysis L.L.C. (SALLC), which is composed of the industrial companies, in cooperation with the staffs of the Laboratory of Advanced Science and Technology for Industry in University of Hyogo. Industrial users can be assisted by staffs of SALLC in the measurement at BL-5. (author)

  6. Characterization of a next-generation piezo bimorph X-ray mirror for synchrotron beamlines.

    Science.gov (United States)

    Alcock, Simon G; Nistea, Ioana; Sutter, John P; Sawhney, Kawal; Fermé, Jean Jacques; Thellièr, Christophe; Peverini, Luca

    2015-01-01

    Piezo bimorph mirrors are versatile active optics used on many synchrotron beamlines. However, many bimorphs suffer from the `junction effect': a periodic deformation of the optical surface which causes major aberrations to the reflected X-ray beam. This effect is linked to the construction of such mirrors, where piezo ceramics are glued directly below the thin optical substrate. In order to address this problem, a next-generation bimorph with piezos bonded to the side faces of a monolithic substrate was developed at Thales-SESO and optimized at Diamond Light Source. Using metrology feedback from the Diamond-NOM, the optical slope error was reduced to ∼ 0.5 µrad r.m.s. for a range of ellipses. To maximize usability, a novel holder was built to accommodate the substrate in any orientation. When replacing a first-generation bimorph on a synchrotron beamline, the new mirror significantly improved the size and shape of the reflected X-ray beam. Most importantly, there was no evidence of the junction effect even after eight months of continuous beamline usage. It is hoped that this new design will reinvigorate the use of active bimorph optics at synchrotron and free-electron laser facilities to manipulate and correct X-ray wavefronts.

  7. High precision mirror alignment mechanism for use in synchrotron radiation beamlines

    International Nuclear Information System (INIS)

    Verma, Adu; Srivastava, P.K.; Das, Suraj; Nookaraju, Mogali

    2009-01-01

    The performance of a synchrotron radiation beamline is highly depends on parameters, crucially on the manufacturing accuracies of the optical elements and very good alignment of optical elements in the beam path. To develop a synchrotron beamline the misalignment effects have to be estimated and the mechanical components that hold optical elements have to be designed and developed within the specified tolerance limits. The translational inaccuracies result in shifting the image spot, which affect the flux throughput. The misorientation errors i.e. the rotation of optical elements about their mean position affects the image quality. The horizontal misorientation i.e. the rotation of an optical element about an axis passing through its centre and perpendicular to the plane containing the mirror has the most sever effect on the spectral resolution of the beamline, because of an increase in the dispersive spot size at the image plane. The design development and testing of a high precision mirror alignment mechanism is reported in this abstract. Though this mirror alignment mechanism is developed for the X-ray diffraction beamline on synchrotron radiation source Indus-2, 2.5 GeV, 300 mA, the design is general purpose and can be adapted for any other synchrotron facility or a similar ultra high vacuum environment. The mirror alignment mechanism is based on a constrained kinematic chain which provides the angular motions about three co-ordinate axes in the range of 0 to ±1° with the backlash free resolution of 1 arc second. The linear motions in three orthogonal directions are performed by other kinematic mounts in the range of 0 to ± 10 mm with a fine adjustment of 10 μm. The motions are transferred from air to ultra high vacuum through bellows. The ultra high vacuum chamber has been designed, fabricated and tested as per the ASME code. The rotational motions of the mirror alignment mechanism has been tested using a laser interferometer. (author)

  8. Characterization of a next-generation piezo bimorph X-ray mirror for synchrotron beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Alcock, Simon G., E-mail: simon.alcock@diamond.ac.uk; Nistea, Ioana; Sutter, John P.; Sawhney, Kawal [Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE (United Kingdom); Fermé, Jean-Jacques; Thellièr, Christophe; Peverini, Luca [Thales-SESO, 305 rue Louis Armand, Pôle d’Activités d’Aix les Milles, Aix-en-Provence (France)

    2015-01-01

    A next-generation bimorph mirror with piezos bonded to the side faces of a monolithic substrate was created. When replacing a first-generation bimorph mirror suffering from the junction effect, the new type of mirror significantly improved the size and shape of the reflected synchrotron X-ray beam. No evidence of the junction effect was observed even after eight months of continuous beamline usage. Piezo bimorph mirrors are versatile active optics used on many synchrotron beamlines. However, many bimorphs suffer from the ‘junction effect’: a periodic deformation of the optical surface which causes major aberrations to the reflected X-ray beam. This effect is linked to the construction of such mirrors, where piezo ceramics are glued directly below the thin optical substrate. In order to address this problem, a next-generation bimorph with piezos bonded to the side faces of a monolithic substrate was developed at Thales-SESO and optimized at Diamond Light Source. Using metrology feedback from the Diamond-NOM, the optical slope error was reduced to ∼0.5 µrad r.m.s. for a range of ellipses. To maximize usability, a novel holder was built to accommodate the substrate in any orientation. When replacing a first-generation bimorph on a synchrotron beamline, the new mirror significantly improved the size and shape of the reflected X-ray beam. Most importantly, there was no evidence of the junction effect even after eight months of continuous beamline usage. It is hoped that this new design will reinvigorate the use of active bimorph optics at synchrotron and free-electron laser facilities to manipulate and correct X-ray wavefronts.

  9. Characterization of a next-generation piezo bimorph X-ray mirror for synchrotron beamlines

    International Nuclear Information System (INIS)

    Alcock, Simon G.; Nistea, Ioana; Sutter, John P.; Sawhney, Kawal; Fermé, Jean-Jacques; Thellièr, Christophe; Peverini, Luca

    2015-01-01

    A next-generation bimorph mirror with piezos bonded to the side faces of a monolithic substrate was created. When replacing a first-generation bimorph mirror suffering from the junction effect, the new type of mirror significantly improved the size and shape of the reflected synchrotron X-ray beam. No evidence of the junction effect was observed even after eight months of continuous beamline usage. Piezo bimorph mirrors are versatile active optics used on many synchrotron beamlines. However, many bimorphs suffer from the ‘junction effect’: a periodic deformation of the optical surface which causes major aberrations to the reflected X-ray beam. This effect is linked to the construction of such mirrors, where piezo ceramics are glued directly below the thin optical substrate. In order to address this problem, a next-generation bimorph with piezos bonded to the side faces of a monolithic substrate was developed at Thales-SESO and optimized at Diamond Light Source. Using metrology feedback from the Diamond-NOM, the optical slope error was reduced to ∼0.5 µrad r.m.s. for a range of ellipses. To maximize usability, a novel holder was built to accommodate the substrate in any orientation. When replacing a first-generation bimorph on a synchrotron beamline, the new mirror significantly improved the size and shape of the reflected X-ray beam. Most importantly, there was no evidence of the junction effect even after eight months of continuous beamline usage. It is hoped that this new design will reinvigorate the use of active bimorph optics at synchrotron and free-electron laser facilities to manipulate and correct X-ray wavefronts

  10. Beamline for X-ray Free Electron Laser of SACLA

    International Nuclear Information System (INIS)

    Tono, K; Togashi, T; Ohashi, H; Kimura, H; Takahashi, S; Takeshita, K; Tomizawa, H; Goto, S; Inubushi, Y; Sato, T; Yabashi, M

    2013-01-01

    A beamline for X-ray free electron laser (XFEL) has been developed at SACLA, SPring-8 Angstrom Compact free electron LAser. The beamline delivers and diagnoses an XFEL beam without degrading the beam quality. The transport optics are applicable in the range of 4–30 keV with a double-crystal monochromator or 4–15 keV with either of two double-mirror systems. A photon diagnostic system of the beamline monitors intensity, photon energy, center-of-mass position, and spatial profile in shot-by-shot and non-destructive manners.

  11. The BESSY X-ray microfocus beamline project

    International Nuclear Information System (INIS)

    Erko, A.; Schaefers, F.; Firsov, A.; Peatman, W.B.; Eberhardt, W.; Signorato, R.

    2004-01-01

    The design and construction of a beamline dedicated to X-ray absorption spectroscopy, X-ray fluorescence analysis, X-ray diffraction and X-ray small-angle scattering measurements with micron and submicron spatial resolution in the photon energy range of 1.9-30 keV are reported here. The main feature of the beamline is a combination of all these methods in one experimental station. The source will be a BESSY 7-T wavelength shifter, which is already in operation. Such a wavelength shifter with its continuous spectrum is an optimum source for these experiments. Glass capillaries and the combination of a linear Bragg-Fresnel lens and bimorph mirror were chosen as the special optical components in the beamline. This beamline will open for BESSY users the possibility to perform experiments on the same sample applying a microfocused X-ray beam in combination with advanced experimental methods

  12. TREFF: Reflectometer and instrument component test beamline at MLZ

    Directory of Open Access Journals (Sweden)

    Peter Link

    2017-11-01

    Full Text Available TREFF is a high resolution polarized neutron reflectometer and instrument component test beamline resulting in a highly modular instrument providing a flexible beam line for various applications.

  13. Synchrotron total reflection X-ray fluorescence at BL-16 microfocus beamline of Indus-2

    Energy Technology Data Exchange (ETDEWEB)

    Tiwari, M. K., E-mail: mktiwari@rrcat.gov.in; Singh, A. K., E-mail: mktiwari@rrcat.gov.in; Das, Gangadhar, E-mail: mktiwari@rrcat.gov.in; Chowdhury, Anupam, E-mail: mktiwari@rrcat.gov.in; Lodha, G. S., E-mail: mktiwari@rrcat.gov.in [Indus Synchrotrons Utilisation Division, Raja Ramanna Centre for Advanced Technology, Indore-452013 (India)

    2014-04-24

    Determination of ultra trace elements is important in many disciplines both in basic and applied sciences. Numerous applications show their importance in medical science, environmental science, materials science, food processing and semiconductor industries and in maintaining the quality control of ultra pure chemicals and reagents. We report commissioning of a synchrotron based total reflection x-ray fluorescence (TXRF) facility on the BL-16 microfocus beamline of Indus-2. This paper describes the performance of the BL-16 TXRF spectrometer and the detailed description of its capabilities through examples of measured results.

  14. Experimental stations at I13 beamline at Diamond Light Source

    Science.gov (United States)

    Pešić, Z. D.; De Fanis, A.; Wagner, U.; Rau, C.

    2013-03-01

    The I13 beamline of Diamond Light Source has been operational since December 2011. The beamline encompass two fully independent branches devoted to coherent imaging experiments (coherent x-ray diffraction, coherent diffraction imaging and ptychography) and x-ray imaging (in-line phase contrast imaging, tomography and full-field microscopy). This paper gives an overview of the current status of experimental stations on both branches and outlines planned developments.

  15. Experimental stations at I13 beamline at Diamond Light Source

    International Nuclear Information System (INIS)

    Pešić, Z D; Fanis, A De; Wagner, U; Rau, C

    2013-01-01

    The I13 beamline of Diamond Light Source has been operational since December 2011. The beamline encompass two fully independent branches devoted to coherent imaging experiments (coherent x-ray diffraction, coherent diffraction imaging and ptychography) and x-ray imaging (in-line phase contrast imaging, tomography and full-field microscopy). This paper gives an overview of the current status of experimental stations on both branches and outlines planned developments.

  16. Current schemes for National Synchrotron Light Source UV beamlines

    International Nuclear Information System (INIS)

    Williams, G.P.; Howells, M.R.; McKinney, W.R.

    1979-01-01

    We describe in some detail four beamlines proposed for the National Synchrotron Light Source uv ring at Brookhaven National Laboratory. Three grazing-incidence instruments, one of the plane grating Mijake type and two with toroidal gratings at grazing angles of 2-1/2 0 and 15 0 are described. Two normal incidence instruments, one using the source as entrance slit and accepting 75 milliradians horizontally are also discussed. In each case we have estimated the output fluxes expected from such beamlines

  17. An overview of what is required and when for developing a beamline at the ALS

    International Nuclear Information System (INIS)

    Hussain, Z.

    1995-08-01

    This report discusses these topics: reviews required for developing a beamline at the ALS; work items and documentation required for the beamline design review; information to be communicated to the ALS staff before the beamline readiness review; work items and documentation required for the beamline readiness review; contacts for information, technical questions, and sources of additional information; and checklist of what is required and when for developing a beamline

  18. A study on radiation shielding and safety analysis for a synchrotron radiation beamline

    International Nuclear Information System (INIS)

    Asano, Yoshihiro

    2001-03-01

    Methods of shielding design and safety analysis are presented for a beam-line of synchrotron radiation. This paper consists of the shielding and safety study of synchrotron radiation with extremely intense and low energy photon below several hundreds keV, and the study for the behavior of remarkable high-energy photons up to 8 GeV, which can creep into beam-lines. A new shielding design code, STAC8 was developed to estimate the leakage dose outside the beam line hutch (an enclosure of the beam, optical elements or experimental instruments) easily and quickly with satisfactory accuracy. The code can calculate consistently from sources of synchrotron radiation to dose equivalent outside hutches with considering the build up effect and polarization effect. Validity of the code was verified by comparing its calculations with those of Monte Carlo simulations and measurement results of the doses inside the hutch of the BL14C of Photon Factory in the High Energy Accelerator Research Organization (KEK), showing good agreements. The shielding design calculations using STAC8 were carried out to apply to the practical beam-lines with the considering polarization effect and clarified the characteristics of the typical beam-line of the third generation synchrotron radiation facility, SPring-8. In addition, the shielding calculations were compared with the measurement outside the shield wall of the bending magnet beam-line of SPring-8, and showed fairly good agreement. The new shielding problems, which have usually been neglected in shielding designs for existing synchrotron radiation facilities, are clarified through the analysis of the beam-line shielding of SPring-8. The synchrotron radiation from the SPring-8 has such extremely high-intensity involving high energy photons that the scattered synchrotron radiation from the concrete floor of the hutch, the ground shine, causes a seriously high dose. The method of effective shielding is presented. For the estimation of the gas

  19. A study on radiation shielding and safety analysis for a synchrotron radiation beamline

    Energy Technology Data Exchange (ETDEWEB)

    Asano, Yoshihiro [Japan Atomic Energy Research Inst., Kansai Research Establishment, Synchrotron Radiation Research Center, Mikazuhi, Hyogo (Japan)

    2001-03-01

    Methods of shielding design and safety analysis are presented for a beam-line of synchrotron radiation. This paper consists of the shielding and safety study of synchrotron radiation with extremely intense and low energy photon below several hundreds keV, and the study for the behavior of remarkable high-energy photons up to 8 GeV, which can creep into beam-lines. A new shielding design code, STAC8 was developed to estimate the leakage dose outside the beam line hutch (an enclosure of the beam, optical elements or experimental instruments) easily and quickly with satisfactory accuracy. The code can calculate consistently from sources of synchrotron radiation to dose equivalent outside hutches with considering the build up effect and polarization effect. Validity of the code was verified by comparing its calculations with those of Monte Carlo simulations and measurement results of the doses inside the hutch of the BL14C of Photon Factory in the High Energy Accelerator Research Organization (KEK), showing good agreements. The shielding design calculations using STAC8 were carried out to apply to the practical beam-lines with the considering polarization effect and clarified the characteristics of the typical beam-line of the third generation synchrotron radiation facility, SPring-8. In addition, the shielding calculations were compared with the measurement outside the shield wall of the bending magnet beam-line of SPring-8, and showed fairly good agreement. The new shielding problems, which have usually been neglected in shielding designs for existing synchrotron radiation facilities, are clarified through the analysis of the beam-line shielding of SPring-8. The synchrotron radiation from the SPring-8 has such extremely high-intensity involving high energy photons that the scattered synchrotron radiation from the concrete floor of the hutch, the ground shine, causes a seriously high dose. The method of effective shielding is presented. For the estimation of the gas

  20. Data Management System at the Photon Factory Macromolecular Crystallography Beamline

    International Nuclear Information System (INIS)

    Yamada, Y; Matsugaki, N; Chavas, L M G; Hiraki, M; Igarashi, N; Wakatsuki, S

    2013-01-01

    Macromolecular crystallography is a very powerful tool to investigate three-dimensional structures of macromolecules at the atomic level, and is widely spread among structural biology researchers. Due to recent upgrades of the macromolecular crystallography beamlines at the Photon Factory, beamline throughput has improved, allowing more experiments to be conducted during a user's beam time. Although the number of beamlines has increased, so has the number of beam time applications. Consequently, both the experimental data from users' experiments and data derived from beamline operations have dramatically increased, causing difficulties in organizing these diverse and large amounts of data for the beamline operation staff and users. To overcome this problem, we have developed a data management system by introducing commercial middleware, which consists of a controller, database, and web servers. We have prepared several database projects using this system. Each project is dedicated to a certain aspect such as experimental results, beam time applications, beam time schedule, or beamline operation reports. Then we designed a scheme to link all the database projects.

  1. The INE-Beamline for Actinide Research at ANKA

    Science.gov (United States)

    Brendebach, Boris; Denecke, Melissa A.; Rothe, Jörg; Dardenne, Kathy; Römer, Jürgen

    2007-02-01

    The INE-Beamline for actinide research at the synchrotron source ANKA is now fully operational. This beamline was designed, built, and commissioned by the Institut für Nukleare Entsorgung (INE) at the Forschungszentrum Karlsruhe (FZK), Germany. It is dedicated to actinide speciation investigations related to nuclear waste disposal as well as applied and basic actinide research. Experiments on radioactive samples with activities up to 106 times the limit of exemption inside a safe and flexible double containment concept are possible. The close proximity of the beamline to INE's active laboratories is unique in Europe. Currently, experiments can be performed in an X-ray energy range from around 2.15 keV (P K edge) to 24.35 keV (Pd K edge). The INE-Beamline design is optimized for spectroscopy with emphasis on surface sensitive techniques. A microfocus option is presently being installed at the INE-Beamline. Access to the INE-Beamline is possible through cooperation with INE, through the ANKA proposal system and via the European Network of Excellence for Actinide Sciences (ACTINET).

  2. Capillary concentrators for synchrotron radiation beamlines

    International Nuclear Information System (INIS)

    Heald, S.M.; Brewe, D.L.; Kim, K.H.; Brown, F.C.; Barg, B.; Stern, E.A.

    1996-01-01

    Capillary concentrators condense x-rays by multiple reflections down a gradually tapering capillary. They can provide sub-micron beam spots, and are promising candidates for use in the next generation x-ray microprobe beamlines. The weak energy dependence of their properties make them especially useful for energy scanning applications such as micro-XAFS. This paper examines the potential performance of capillary optics for an x-ray microprobe, as well as some practical issues such as fabrication and alignment. Best performance at third generation sources requires long capillaries, and the authors have been using fiber optics techniques to fabricate capillaries up to one meter in length. The performance of shorter (less than about 0.5 m) capillaries has often been found to agree well with theoretical calculations, indicating the inner surface is a high quality x-ray reflector. These capillaries have been tested at the NSLS for imaging and micro-XAFS down to 2.6 microm resolution with excellent results. On an unfocused bend magnet line flux density approaching 10 6 ph/sec/microm 2 has been achieved. While nearly optimum profiles have been achieved for longer capillaries, the results have been disappointing, and alignment problems are suspected. The dramatic improvement in performance possible at third generation synchrotrons such as the APS is discussed along with improvements possible by using the capillaries in conjunction with coupling optics

  3. Comparação entre dois fios de sutura não absorvíveis na anastomose traqueal término-terminal em cães Comparison of two nonabsorbable suture materials in the end-to-end tracheal anastomosis in dogs

    Directory of Open Access Journals (Sweden)

    Sheila Canevese Rahal

    1995-01-01

    Full Text Available Doze cães sem raça definida, com idade variando entre 1 e 6 anos e peso de 6 a 20kg, foram submetidos a ressecção traqueal e anastomose término-terminal, na qual foram testados os fios poliéster trançado não capilar e náilon monofilamento. Seis animais, cada três com um mesmo tipo de fio de sutura, sofreram a excisão equivalente a três anéis traqueais. Com 15 dias foi executada uma nova intervenção onde se ressecou o equivalente a mais seis anéis, perfazendo um total de nove. Ao final de outros 15 dias foram sacrificados. Os outros seis animais, cada três com um mesmo tipo de fio, foram submetidos à excisão equivalente a três anéis traqueais e mantidos por 43 dias. As traquéias foram avaliadas por exames clínicos, radiográficos, macroscópicos e histopatológicos. O fio de náilon monofilamento apresentou menos reação tecidual do que o poliéster trançado não capilar, promoveu uma anastomose segura e com menor chance de formação de granuloma.Twelve mongrel dogs, with age between 1 and 6 years old and weight between 12 and 40 pounds, were submitted to tracheal resection and end-to-end anastomosis in which were tested braided polyester no capillary and monofilament nylon materiais. Six animais, every threeones with a same type of suture material, suffered the excision equivalent to three tracheal rings. A new intervention was performed with fifteen days, in which the equivalent of more six tracheal rings were removed, completing the total of nine. At the end of more fifteen days they were sacrificed. The other six animals, every three with a same type of suture material, were submitted to the excision equivalent to three tracheal rings and maintained for 43 days. The tracheal anastomosis were evaluated to clinic, radiographic, macroscopic and histopathologic studies. The monofilament nylon material exhibited less reaction than polyester and promoted a secure anastomosis with less risk of granuloma formation.

  4. Diamond beamline I07: a beamline for surface and interface diffraction.

    Science.gov (United States)

    Nicklin, Chris; Arnold, Tom; Rawle, Jonathan; Warne, Adam

    2016-09-01

    Beamline I07 at Diamond Light Source is dedicated to the study of the structure of surfaces and interfaces for a wide range of sample types, from soft matter to ultrahigh vacuum. The beamline operates in the energy range 8-30 keV and has two endstations. The first houses a 2+3 diffractometer, which acts as a versatile platform for grazing-incidence techniques including surface X-ray diffraction, grazing-incidence small- (and wide-) angle X-ray scattering, X-ray reflectivity and grazing-incidence X-ray diffraction. A method for deflecting the X-rays (a double-crystal deflector) has been designed and incorporated into this endstation, extending the surfaces that can be studied to include structures formed on liquid surfaces or at liquid-liquid interfaces. The second experimental hutch contains a similar diffractometer with a large environmental chamber mounted on it, dedicated to in situ ultrahigh-vacuum studies. It houses a range of complementary surface science equipment including a scanning tunnelling microscope, low-energy electron diffraction and X-ray photoelectron spectroscopy ensuring that correlations between the different techniques can be performed on the same sample, in the same chamber. This endstation allows accurate determination of well ordered structures, measurement of growth behaviour during molecular beam epitaxy and has also been used to measure coherent X-ray diffraction from nanoparticles during alloying.

  5. Conceptual design of an undulator system for a dedicated bio-imaging beamline at the European X-ray FEL

    Energy Technology Data Exchange (ETDEWEB)

    Geloni, Gianluca [European XFEL GmbH, Hamburg (Germany); Kocharyan, Vitali; Saldin, Evgeni [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-05-15

    We describe a future possible upgrade of the European XFEL consisting in the construction of an undulator beamline dedicated to life science experiments. The availability of free undulator tunnels at the European XFEL facility offers a unique opportunity to build a beamline optimized for coherent diffraction imaging of complex molecules, like proteins and other biologically interesting structures. Crucial parameters for such bio-imaging beamline are photon energy range, peak power, and pulse duration. Key component of the setup is the undulator source. The peak power is maximized in the photon energy range between 3 keV and 13 keV by the use of a very efficient combination of self-seeding, fresh bunch and tapered undulator techniques. The unique combination of ultra-high peak power of 1 TW in the entire energy range, and ultrashort pulse duration tunable from 2 fs to 10 fs, would allow for single shot coherent imaging of protein molecules with size larger than 10 nm. Also, the new beamline would enable imaging of large biological structures in the water window, between 0.3 keV and 0.4 keV. In order to make use of standardized components, at present we favor the use of SASE3-type undulator segments. The number segments, 40, is determined by the tapered length for the design output power of 1 TW. The present plan assumes the use of a nominal electron bunch with charge of 0.1 nC. Experiments will be performed without interference with the other three undulator beamlines. Therefore, the total amount of scheduled beam time per year is expected to be up to 4000 hours.

  6. Support for the Advanced Polymers Beamline at the National Synchrotron Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Hsiao, Benjamin S. [State Univ. of New York (SUNY), Stonybrook, NY (United States)

    2008-10-01

    The primary focus of the X27C beamline is to investigate frontier polymer science and engineering problems with emphasis on real-time studies of structures, morphologies and dynamics from atomic, nanoscopic, microscopic to mesoscopic scales using simultaneous small-angle X-ray scattering (SAXS) and wide-angle X-ray diffraction (WAXD) techniques. The scientific merit of this project is as follows. Currently, many unique sample chambers for in-situ synchrotron studies, developed by the PI (B. Hsiao) and Co-PI (B. Chu), are available for general users of X27C at NSLS. These instruments include a gel/melt spinning apparatus, a continuous fiber drawing apparatus, a tensile stretching apparatus, a high pressure X-ray cell using supercritical carbon dioxide, a parallel plate strain-controlled shear stage and a dynamic rheometer for small-strain oscillatory deformation study. Based on the use of these instruments in combination with synchrotron X-rays, many new insights into the relationships between processing and structure have been obtained in recent years. The broader impact of this project is as follows. The X27C beamline is the first synchrotron facility in the United States dedicated to chemistry/materials research (with emphasis on polymers). The major benefit of this facility to the materials community is that no extensive synchrotron experience and equipment preparation are required from general users to carry out cutting-edge experiments.

  7. A beamline for macromolecular crystallography at the Advanced Light Source

    International Nuclear Information System (INIS)

    Padmore, H.A.; Earnest, T.; Kim, S.H.; Thompson, A.C.; Robinson, A.L.

    1994-08-01

    A beamline for macromolecular crystallography has been designed for the ALS. The source will be a 37-pole wiggler with a, 2-T on-axis peak field. The wiggler will illuminate three beamlines, each accepting 3 mrad of horizontal aperture. The central beamline will primarily be used for multiple-wavelength anomalous dispersion measurements in the wavelength range from 4 to 0.9 angstrom. The beamline optics will comprise a double-crystal monochromator with a collimating pre-mirror and a double-focusing mirror after the monochromator. The two side stations will be used for fixed-wavelength experiments within the wavelength range from 1.5 to 0.95 angstrom. The optics will consist of a conventional vertically focusing cylindrical mirror followed by an asymmetrically cut curved-crystal monochromator. This paper presents details of the optimization of the wiggler source for crystallography, gives a description of the beamline configuration, and discusses the reasons for the choices made

  8. The Scanning Nanoprobe Beamline Nanoscopium at Synchrotron Soleil

    Science.gov (United States)

    Somogyi, A.; Kewish, C. M.; Polack, F.; Moreno, T.

    2011-09-01

    The Nanoscopium beamline at Synchrotron Soleil will offer advanced scanning-based hard x-ray imaging techniques in the 5- to 20-keV energy range, for user communities working in the earth, environmental, and life sciences. Two dedicated end stations will exploit x-ray coherence to produce images in which contrast is based on a range of physical processes. In the first experiment hutch, coherent scatter imaging techniques will produce images in which contrast arises from spatial variations in the complex refractive index, and orientation in the nanostructure of samples. In the second experiment hutch, elemental mapping will be carried out at the trace (ppm) level by scanning x-ray fluorescence, speciation mapping by XANES, and phase gradient mapping by scanning differential phase contrast imaging. The beamline aims to reach sub-micrometric, down to 30 nm, spatial resolution. This ˜155-meter-long beamline will share the straight section with a future tomography beamline by using canted undulators having 6.5-mrad separation angle. The optical design of Nanoscopium aims to reduce the effect of instabilities on the probing nanobeam by utilizing an all-horizontal geometry for the reflections of the primary beamline mirrors, which focus onto a slit, creating an over-filled secondary source. Kirkpatrick-Baez mirrors and Fresnel zone plates will be used as focusing devices in the experiment hutches. Nanoscopium is expected to commence user operation in 2013.

  9. Upgrade of Spring-8 Beamline Network with Vlan Technology Over Gigabit Ethernet

    OpenAIRE

    Ishii, M.; Fukui, T.; Furukawa, Y.; Nakatani, T.; Ohata, T.; Tanaka, R.

    2001-01-01

    The beamline network system at SPring-8 consists of three LANs; a BL-LAN for beamline component control, a BL-USER-LAN for beamline experimental users and an OA-LAN for the information services. These LANs are interconnected by a firewall system. Since the network traffic and the number of beamlines have increased, we upgraded the backbone of BL-USER-LAN from Fast Ethernet to Gigabit Ethernet. And then, to establish the independency of a beamline and to raise flexibility of every beamline, we...

  10. Facilities for small-molecule crystallography at synchrotron sources.

    Science.gov (United States)

    Barnett, Sarah A; Nowell, Harriott; Warren, Mark R; Wilcox, Andrian; Allan, David R

    2016-01-01

    Although macromolecular crystallography is a widely supported technique at synchrotron radiation facilities throughout the world, there are, in comparison, only very few beamlines dedicated to small-molecule crystallography. This limited provision is despite the increasing demand for beamtime from the chemical crystallography community and the ever greater overlap between systems that can be classed as either small macromolecules or large small molecules. In this article, a very brief overview of beamlines that support small-molecule single-crystal diffraction techniques will be given along with a more detailed description of beamline I19, a dedicated facility for small-molecule crystallography at Diamond Light Source.

  11. High-resolution inner-shell spectroscopies of free atoms and molecules using soft-x-ray beamlines at the third-generation synchrotron radiation sources

    International Nuclear Information System (INIS)

    Ueda, Kiyoshi

    2003-01-01

    This article reviews the current status of inner-shell spectroscopies of free atoms and molecules using high-resolution soft-x-ray monochromators installed in the soft-x-ray beamlines at the third-generation synchrotron radiation facilities. Beamlines and endstations devoted to atomic and molecular inner-shell spectroscopies and various types of experimental techniques, such as ion yield spectroscopy, resonant photoemission spectroscopy and multiple-coincidence momentum imaging, are described. Experimental results for K-shell excitation of Ne, O K-shell excitation of H 2 O and CO 2 , C K-shell excitation and ionization of CO 2 and B K-shell excitation of BF 3 , obtained at beamline 27SU of SPring-8 in Japan, are discussed as examples of atomic and molecular inner-shell spectroscopies using the third-generation synchrotron radiation sources. (topical review)

  12. Justification for the development of a bending magnet beamline at sector 10 at the APS

    International Nuclear Information System (INIS)

    Kemner, K. M.; Biosciences Division

    2006-01-01

    The long-planned and much-needed merger of EnviroCAT into the Materials Research Collaborative Access Team (MR-CAT) will provide dedicated state-of-the-art facilities that are critical to research on a broad range of issues in environmental sciences. These CATs will focus on developing a bending magnet (BM) beamline for x-ray absorption fine structure (XAFS) and micro x-ray analysis of environmental samples through integration with existing insertion device (ID) capabilities in XAFS, micro x-ray analysis, and x-ray scattering. In addition, the expanded MR-CAT will serve as the hub of personnel and laboratory infrastructure support for molecular environmental science and biogeochemical science at the Advanced Photon Source (APS). In conjunction with the merger of EnviroCAT into MR-CAT, the US Environmental Protection Agency (EPA) will become a member institution of MR-CAT, joining the present members (University of Notre Dame, Illinois Institute of Technology, University of Florida, British Petroleum, and Argonne's Chemical Engineering and Biosciences Division). The motivation for blending capabilities meeting the needs of EnviroCAT users into the MR-CAT facilities is the explosion of synchrotron-radiation-based research in the field known as molecular environmental science (MES). This research is driven largely by the need to remediate contaminated environmental materials and to understand the scientific foundations that govern contaminant transport in the environment. Synchrotron radiation is playing a crucial role in solving environmental science problems by offering x-ray-based analytical techniques for detailed molecular- and atomic-level studies of these systems. This document focuses on the scientific justification for developing a specific type of BM beamline capability at Sector 10 for XAFS and micro x-ray analysis to support the growing MES community. However, the modification of Sector 10 will meet other future needs by providing (1) an existing undulator

  13. Justification for the development of a bending magnet beamline at sector 10 at the APS.

    Energy Technology Data Exchange (ETDEWEB)

    Kemner, K. M.; Biosciences Division

    2006-09-18

    The long-planned and much-needed merger of EnviroCAT into the Materials Research Collaborative Access Team (MR-CAT) will provide dedicated state-of-the-art facilities that are critical to research on a broad range of issues in environmental sciences. These CATs will focus on developing a bending magnet (BM) beamline for x-ray absorption fine structure (XAFS) and micro x-ray analysis of environmental samples through integration with existing insertion device (ID) capabilities in XAFS, micro x-ray analysis, and x-ray scattering. In addition, the expanded MR-CAT will serve as the hub of personnel and laboratory infrastructure support for molecular environmental science and biogeochemical science at the Advanced Photon Source (APS). In conjunction with the merger of EnviroCAT into MR-CAT, the US Environmental Protection Agency (EPA) will become a member institution of MR-CAT, joining the present members (University of Notre Dame, Illinois Institute of Technology, University of Florida, British Petroleum, and Argonne's Chemical Engineering and Biosciences Division). The motivation for blending capabilities meeting the needs of EnviroCAT users into the MR-CAT facilities is the explosion of synchrotron-radiation-based research in the field known as molecular environmental science (MES). This research is driven largely by the need to remediate contaminated environmental materials and to understand the scientific foundations that govern contaminant transport in the environment. Synchrotron radiation is playing a crucial role in solving environmental science problems by offering x-ray-based analytical techniques for detailed molecular- and atomic-level studies of these systems. This document focuses on the scientific justification for developing a specific type of BM beamline capability at Sector 10 for XAFS and micro x-ray analysis to support the growing MES community. However, the modification of Sector 10 will meet other future needs by providing (1) an existing

  14. The new NCPSS BL19U2 beamline at the SSRF for small-angle X-ray scattering from biological macromolecules in solution.

    Science.gov (United States)

    Li, Na; Li, Xiuhong; Wang, Yuzhu; Liu, Guangfeng; Zhou, Ping; Wu, Hongjin; Hong, Chunxia; Bian, Fenggang; Zhang, Rongguang

    2016-10-01

    The beamline BL19U2 is located in the Shanghai Synchrotron Radiation Facility (SSRF) and is its first beamline dedicated to biological material small-angle X-ray scattering (BioSAXS). The electrons come from an undulator which can provide high brilliance for the BL19U2 end stations. A double flat silicon crystal (111) monochromator is used in BL19U2, with a tunable monochromatic photon energy ranging from 7 to 15 keV. To meet the rapidly growing demands of crystallographers, biochemists and structural biologists, the BioSAXS beamline allows manual and automatic sample loading/unloading. A Pilatus 1M detector (Dectris) is employed for data collection, characterized by a high dynamic range and a short readout time. The highly automated data processing pipeline SASFLOW was integrated into BL19U2, with help from the BioSAXS group of the European Molecular Biology Laboratory (EMBL, Hamburg), which provides a user-friendly interface for data processing. The BL19U2 beamline was officially opened to users in March 2015. To date, feedback from users has been positive and the number of experimental proposals at BL19U2 is increasing. A description of the new BioSAXS beamline and the setup characteristics is given, together with examples of data obtained.

  15. Medical research and multidisciplinary applications with laser-accelerated beams: the ELIMED netwotk at ELI-Beamlines

    Science.gov (United States)

    Tramontana, A.; Anzalone, A.; Candiano, G.; Carpinelli, M.; Cirrone, G. A. P.; Cuttone, G.; Korn, G.; Licciardello, T.; Maggiore, M.; Manti, L.; Margarone, D.; Musumarra, A.; Perozziello, F.; Pisciotta, P.; Raffaele, L.; Romano, F.; Romano, F. P.; Stancampiano, C.; Schillaci, F.; Scuderi, V.; Torrisi, L.; Tudisco, S.

    2014-04-01

    Laser accelerated proton beams represent nowadays an attractive alternative to the conventional ones and they have been proposed in different research fields. In particular, the interest has been focused in the possibility of replacing conventional accelerating machines with laser-based accelerators in order to develop a new concept of hadrontherapy facilities, which could result more compact and less expensive. With this background the ELIMED (ELIMED: ELI-Beamlines MEDical applications) research project has been launched by LNS-INFN researchers (Laboratori Nazionali del Sud-Istituto Nazionale di Fisica Nucleare, Catania, IT) and ASCR-FZU researchers (Academy of Sciences of the Czech Republic-Fyzikální ústar, Prague, Cz), within the pan-European ELI-Beamlines facility framework. Its main purposes are the demonstration of future applications in hadrontherapy of optically accelerated protons and the realization of a laser-accelerated ion transport beamline for multidisciplinary applications. Several challenges, starting from laser-target interaction and beam transport development, up to dosimetric and radiobiological issues, need to be overcome in order to reach the final goals. The design and the realization of a preliminary beam handling and dosimetric system and of an advanced spectrometer for high energy (multi-MeV) laser-accelerated ion beams will be shortly presented in this work.

  16. Simulating the Beam-line at CERN's ISOLDE Experiment

    CERN Document Server

    McGrath, Casey

    2013-01-01

    Maximizing the optical matching along portions of the ISOLDE beam-line and automating this procedure will make it easier for scientists to determine what the strengths of the electrical elds of each beam-line element should be in order to reduce particle loss. Simulations are run using a program called MAD-X, however, certain issues were discovered that hindered an immediate success of the simulations. Specifically, the transfer matrices for electrostatic components like the switchyards, kickers, and electric quadrupoles were missing from the original coding. The primary aim of this project was to design these components using AutoCAD and then extract the transfer matrices using SIMION. Future work will then implement these transfer matrices into the MAD-X code to make the simulations of the beam-line more accurate.

  17. The Materials Science beamline upgrade at the Swiss Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Willmott, P. R., E-mail: philip.willmott@psi.ch; Meister, D.; Leake, S. J.; Lange, M.; Bergamaschi, A. [Swiss Light Source, Paul Scherrer Institut, CH-5232 Villigen (Switzerland); and others

    2013-07-16

    The wiggler X-ray source of the Materials Science beamline at the Swiss Light Source has been replaced with a 14 mm-period cryogenically cooled in-vacuum undulator. In order to best exploit the increased brilliance of this new source, the entire front-end and optics have been redesigned. The Materials Science beamline at the Swiss Light Source has been operational since 2001. In late 2010, the original wiggler source was replaced with a novel insertion device, which allows unprecedented access to high photon energies from an undulator installed in a medium-energy storage ring. In order to best exploit the increased brilliance of this new source, the entire front-end and optics had to be redesigned. In this work, the upgrade of the beamline is described in detail. The tone is didactic, from which it is hoped the reader can adapt the concepts and ideas to his or her needs.

  18. Physical optics simulations with PHASE for SwissFEL beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Flechsig, U.; Follath, R.; Reiche, S. [Paul Scherrer Institut, Swiss Light Source, 5232 Villigen PSI (Switzerland); Bahrdt, J. [Helmholtz Zentrum Berlin (Germany)

    2016-07-27

    PHASE is a software tool for physical optics simulation based on the stationary phase approximation method. The code is under continuous development since about 20 years and has been used for instance for fundamental studies and ray tracing of various beamlines at the Swiss Light Source. Along with the planning for SwissFEL a new hard X-ray free electron laser under construction, new features have been added to permit practical performance predictions including diffraction effects which emerge with the fully coherent source. We present the application of the package on the example of the ARAMIS 1 beamline at SwissFEL. The X-ray pulse calculated with GENESIS and given as an electrical field distribution has been propagated through the beamline to the sample position. We demonstrate the new features of PHASE like the treatment of measured figure errors, apertures and coatings of the mirrors and the application of Fourier optics propagators for free space propagation.

  19. Measuring circular dichroism in a capillary cell using the b23 synchrotron radiation CD beamline at diamond light source.

    Science.gov (United States)

    Jávorfi, Tamás; Hussain, Rohanah; Myatt, Daniel; Siligardi, Giuliano

    2010-01-01

    Synchrotron radiation circular dichroism (SRCD) is a well-established method in structural biology. The first UV-VIS beamline dedicated to circular dichroism at Diamond Light Source, a third generation synchrotron facility in South Oxfordshire, has recently become operational and it is now available for the user community. Herein we present an important application of SRCD: the CD measurement of protein solutions in fused silica rectangular capillary cells. This was achieved without the use of any lens between the photoelastic modulator and the photomultiplier tube detectors by exploiting the high photon flux of the collimated beam that can be as little as half a millimeter squared. Measures to minimize or eliminate vacuum-UV protein denaturation effects are discussed. The CD spectra measured in capillaries is a proof of principle to address CD measurements in microdevice systems using the new B23 SRCD beamline. © 2010 Wiley-Liss, Inc.

  20. Preliminary results for X-ray phase contrast micro-tomography on the biomedical imaging beamline at SSRF

    International Nuclear Information System (INIS)

    Chen Rongchang; Du Guohao; Xie Honglan; Deng Biao; Tong Yajun; Hu Wen; Xue Yanling; Chen Can; Ren Yuqi; Zhou Guangzhao; Wang Yudan; Xiao Tiqiao; Xu Hongjie; Zhu Peiping

    2009-01-01

    With X-ray phase contrast micro-tomography(CT), one is able to obtain edge-enhanced image of internal structure of the samples. This allows visualization of the fine internal features for biology tissues, which is not able to resolve by conventional absorption CT. After preliminary modulation, monochromatic X-rays (8-72.5 keV) are available for experiments on the experimental station of the biomedical imaging beamline at Shanghai Synchrotron Radiation Facility(SSRF). In this paper, we report the in line phase contrast micro-tomography(IL-XPCT) of biology sample (locust) on the beamline. The reconstruct slice images and three dimensional rendering images of the locust were obtained, with clearly visible images of locus's wing, surface texture and internal tissue distribution. (authors)

  1. DCS - A high flux beamline for time resolved dynamic compression science – Design highlights

    Energy Technology Data Exchange (ETDEWEB)

    Capatina, D., E-mail: capatina@aps.anl.gov; D’Amico, K., E-mail: kdamico@aps.anl.gov; Nudell, J., E-mail: jnudell@aps.anl.gov; Collins, J., E-mail: collins@aps.anl.gov; Schmidt, O., E-mail: oschmidt@aps.anl.gov [Advanced Photon Source, Argonne National Laboratory, 9700 S. Cass Avenue, Lemont, IL 60439 (United States)

    2016-07-27

    The Dynamic Compression Sector (DCS) beamline, a national user facility for time resolved dynamic compression science supported by the National Nuclear Security Administration (NNSA) of the Department of Energy (DOE), has recently completed construction and is being commissioned at Sector 35 of the Advanced Photon Source (APS) at Argonne National Laboratory (ANL). The beamline consists of a First Optics Enclosure (FOE) and four experimental enclosures. A Kirkpatrick–Baez focusing mirror system with 2.2 mrad incident angles in the FOE delivers pink beam to the experimental stations. A refocusing Kirkpatrick–Baez mirror system is situated in each of the two most downstream enclosures. Experiments can be conducted in either white, monochromatic, pink or monochromatic-reflected beam mode in any of the experimental stations by changing the position of two interlocked components in the FOE. The beamline Radiation Safety System (RSS) components have been designed to handle the continuous beam provided by two in-line revolver undulators with periods of 27 and 30 mm, at closed gap, 150 mA beam current, and passing through a power limiting aperture of 1.5 x 1.0 mm{sup 2}. A novel pink beam end station stop [1] is used to stop the continuous and focused pink beam which can achieve a peak heat flux of 105 kW/mm{sup 2}. A new millisecond shutter design [2] is used to deliver a quick pulse of beam to the sample, synchronized with the dynamic event, the microsecond shutter, and the storage ring clock.

  2. Infrared Spectroscopy Beamline Based on a Tabletop Storage Ring

    OpenAIRE

    Haque, Md. Monirul; Moon, Ahsa; Yamada, Hironari

    2012-01-01

    An optical beamline dedicated to the infrared (IR) spectroscopy has been constructed at MIRRORCLE, a tabletop storage ring. The beamline has been designed for the use of infrared synchrotron radiation (IRSR) emitted from a bending magnet of 156 mm bending radius with the acceptance angle of 355(H) × 138(V) mrad to obtain high flux. The IR emission is forced by an exactly circular optics, named photon storage ring (PhSR), placed around the electron orbit and is collected by a “magic mirror” as...

  3. High Power Primary Slits For The ESRF Beamlines

    International Nuclear Information System (INIS)

    Marion, Philippe; Zhang Lin

    2004-01-01

    At the ESRF, in order to face the increased heatload on the beamlines, new Primary slits have been developed. The main features of the new slits are: beam size = 0 to 4mm; accuracy = 10μm; acceptable power density: 600 W/mm2; acceptable total power: 7kW; total length: 740mm. The adopted design offers a wide water cooled area; the shapes of the heated parts have been optimized to reduce the local thermal stresses. The maximum calculated temperature and stress are 353C and 606MPa. Six of these new slits are now in operation on ESRF Beamlines

  4. A compact cost-effective beamline for a PET Cyclotron

    International Nuclear Information System (INIS)

    Dehnel, M.P.; Jackle, P.; Roeder, M.; Stewart, T.; Theroux, J.; Brasile, J.P.; Sirot, P.; Buckley, K.R.; Bedue, M.

    2007-01-01

    Most commercial PET Cyclotrons have targets mounted on or near the main cyclotron vacuum chamber. There is often little or no system capability for centering or focusing the extracted beam on target to achieve maximum production. This paper describes the ion-optics, design and development of a compact cost-effective beamline comprised of low activation and radiation resistant materials. The beamline, complete with suitable diagnostic devices, permits the extracted proton beam to be centered (X-Y steering magnet), and focused (quadrupole doublet) on target eliminating unnecessary beamspill and ensuring high production

  5. APS beamline standard components handbook, Version 1.3

    International Nuclear Information System (INIS)

    Hahn, U.; Shu, D.; Kuzay, T.M.

    1993-02-01

    This Handbook in its current version (1.3) contains descriptions, specifications, and preliminary engineering design drawings for many of the standard components. The design status and schedules have been provided wherever possible. In the near future, the APS plans to update engineering drawings of identified standard beamline components and complete the Handbook. The completed version of this Handbook will become available to both the CATs and potential vendors. Use of standard components should result in major cost reductions for CATs in the areas of beamline design and construction

  6. Status of the Nanoscopium scanning nanoprobe beamline of Synchrotron Soleil

    Science.gov (United States)

    Somogyi, A.; Medjoubi, K.; Kewish, C. M.; Leroux, V.; Ribbens, M.; Baranton, G.; Polack, F.; Samama, J. P.

    2013-09-01

    The Nanoscopium 155 m-long scanning nanoprobe beamline of Synchrotron Soleil (St Aubin, France) is dedicated to quantitative multi-modal imaging. Dedicated experimental stations, working in consecutive operation mode, will provide coherent scatter imaging and spectro-microscopy techniques in the 5-20 keV energy range for various user communities. Next to fast scanning, cryogenic cooling will reduce the radiation damage of sensitive samples during the measurements. Nanoscopium is in the construction phase, the first user experiments are expected in 2014. The main characteristics of the beamline and an overview of its status are given in this contribution.

  7. The European Synchrotron Radiation Facility - an overview of planned diffraction capability

    International Nuclear Information System (INIS)

    Kvick, A.

    1991-01-01

    The European Synchrotron Radiation Facility (ESRF) is a third generation synchrotron radiation facility presently being built as a joint venture between 12 European countries in Grenoble, France. The ESRF will be a low emittance 6 GeV storage ring aimed at producing high-brilliance synchrotron radiation from 29 insertion devices and from 27 bending magnet ports. The general user program will start in the middle of 1994 with seven ESRF beam-lines. By 1999, 30 facility beam-lines as well as beam-lines built and financed by Collaborating Research Groups are scheduled to be in operation. The guidelines for the first beam-lines to be constructed as well as a survey of the diffraction oriented beam-lines built by the ESRF are given in the article. (author)

  8. The Pharmaceutical Industry Beamline of Pharmaceutical Consortium for Protein Structure Analysis

    International Nuclear Information System (INIS)

    Nishijima, Kazumi; Katsuya, Yoshio

    2002-01-01

    The Pharmaceutical Industry Beamline was constructed by the Pharmaceutical Consortium for Protein Structure Analysis which was established in April 2001. The consortium is composed of 22 pharmaceutical companies affiliating with the Japan Pharmaceutical Manufacturers Association. The beamline is the first exclusive on that is owned by pharmaceutical enterprises at SPring-8. The specification and equipments of the Pharmaceutical Industry Beamline is almost same as that of RIKEN Structural Genomics Beamline I and II. (author)

  9. Conformal image-guided microbeam radiation therapy at the ESRF biomedical beamline ID17

    International Nuclear Information System (INIS)

    Donzelli, Mattia; Bräuer-Krisch, Elke; Nemoz, Christian; Brochard, Thierry; Oelfke, Uwe

    2016-01-01

    Purpose: Upcoming veterinary trials in microbeam radiation therapy (MRT) demand for more advanced irradiation techniques than in preclinical research with small animals. The treatment of deep-seated tumors in cats and dogs with MRT requires sophisticated irradiation geometries from multiple ports, which impose further efforts to spare the normal tissue surrounding the target. Methods: This work presents the development and benchmarking of a precise patient alignment protocol for MRT at the biomedical beamline ID17 of the European Synchrotron Radiation Facility (ESRF). The positioning of the patient prior to irradiation is verified by taking x-ray projection images from different angles. Results: Using four external fiducial markers of 1.7  mm diameter and computed tomography-based treatment planning, a target alignment error of less than 2  mm can be achieved with an angular deviation of less than 2 ∘ . Minor improvements on the protocol and the use of smaller markers indicate that even a precision better than 1  mm is technically feasible. Detailed investigations concerning the imaging dose lead to the conclusion that doses for skull radiographs lie in the same range as dose reference levels for human head radiographs. A currently used online dose monitor for MRT has been proven to give reliable results for the imaging beam. Conclusions: The ESRF biomedical beamline ID17 is technically ready to apply conformal image-guided MRT from multiple ports to large animals during future veterinary trials.

  10. Particle optics and accelerator modeling software for industrial and laboratory beamline design

    International Nuclear Information System (INIS)

    Gillespie, G.H.; Hill, B.W.

    1998-01-01

    The expanding variety of accelerator applications in research and industry places increased demands upon scientists and engineers involved in developing new accelerator and beamline designs. Computer codes for particle optics simulation have always played an important role in the design process and enhanced software tools offer the promise of improved productivity for beamline designers. This paper summarizes recent work on the development of advanced graphic user interface (GUI) software components, that can be linked directly to many of the standard particle optics programs used in the accelerator community, and which are aimed at turning that promise of improved productivity into a reality. An object oriented programming (OOP) approach has been adopted and a number of GUI components have been developed that run on several different operating systems. The emphasis is on assisting users in the setup and running of the optics programs without requiring any knowledge of the format, syntax, or similar requirements of the input. The components are being linked with several popular optics programs, including TRANSPORT, TURTLE, TRACE 3-D and PARMILA, to form integrated easy-to-use applications. Several advanced applications linking the GUI components with Lie algebra and other high-order simulation codes, as well as system level and facility modeling codes, are also under development. An overview of the work completed to date is presented, and examples of the new tools running on the Windows 95 operating system are illustrated. (orig.)

  11. The test beamline of the European Spallation Source – Instrumentation development and wavelength frame multiplication

    International Nuclear Information System (INIS)

    Woracek, R.; Hofmann, T.; Bulat, M.; Sales, M.; Habicht, K.; Andersen, K.; Strobl, M.

    2016-01-01

    The European Spallation Source (ESS), scheduled to start operation in 2020, is aiming to deliver the most intense neutron beams for experimental research of any facility worldwide. Its long pulse time structure implies significant differences for instrumentation compared to other spallation sources which, in contrast, are all providing short neutron pulses. In order to enable the development of methods and technology adapted to this novel type of source well in advance of the first instruments being constructed at ESS, a test beamline (TBL) was designed and built at the BER II research reactor at Helmholtz-Zentrum Berlin (HZB). Operating the TBL shall provide valuable experience in order to allow for a smooth start of operations at ESS. The beamline is capable of mimicking the ESS pulse structure by a double chopper system and provides variable wavelength resolution as low as 0.5% over a wide wavelength band between 1.6 Å and 10 Å by a dedicated wavelength frame multiplication (WFM) chopper system. WFM is proposed for several ESS instruments to allow for flexible time-of-flight resolution. Hence, ESS will benefit from the TBL which offers unique possibilities for testing methods and components. This article describes the main capabilities of the instrument, its performance as experimentally verified during the commissioning, and its relevance to currently starting ESS instrumentation projects.

  12. Conformal image-guided microbeam radiation therapy at the ESRF biomedical beamline ID17

    Energy Technology Data Exchange (ETDEWEB)

    Donzelli, Mattia, E-mail: donzelli@esrf.fr [European Synchrotron Radiation Facility, 71, Avenue des Martyrs, Grenoble 38000, France and The Institute of Cancer Research, 15 Cotswold Road, Sutton SM2 5NG (United Kingdom); Bräuer-Krisch, Elke; Nemoz, Christian; Brochard, Thierry [European Synchrotron Radiation Facility, 71, Avenue des Martyrs, Grenoble 38000 (France); Oelfke, Uwe [The Institute of Cancer Research, 15 Cotswold Road, Sutton SM2 5NG (United Kingdom)

    2016-06-15

    Purpose: Upcoming veterinary trials in microbeam radiation therapy (MRT) demand for more advanced irradiation techniques than in preclinical research with small animals. The treatment of deep-seated tumors in cats and dogs with MRT requires sophisticated irradiation geometries from multiple ports, which impose further efforts to spare the normal tissue surrounding the target. Methods: This work presents the development and benchmarking of a precise patient alignment protocol for MRT at the biomedical beamline ID17 of the European Synchrotron Radiation Facility (ESRF). The positioning of the patient prior to irradiation is verified by taking x-ray projection images from different angles. Results: Using four external fiducial markers of 1.7  mm diameter and computed tomography-based treatment planning, a target alignment error of less than 2  mm can be achieved with an angular deviation of less than 2{sup ∘}. Minor improvements on the protocol and the use of smaller markers indicate that even a precision better than 1  mm is technically feasible. Detailed investigations concerning the imaging dose lead to the conclusion that doses for skull radiographs lie in the same range as dose reference levels for human head radiographs. A currently used online dose monitor for MRT has been proven to give reliable results for the imaging beam. Conclusions: The ESRF biomedical beamline ID17 is technically ready to apply conformal image-guided MRT from multiple ports to large animals during future veterinary trials.

  13. Construction and characterization of a laser-driven proton beamline at GSI

    Energy Technology Data Exchange (ETDEWEB)

    Busold, Simon

    2014-05-15

    The thesis includes the first experiments with the new 100 TW laser beamline of the PHELIX laser facility at GSI Darmstadt to drive a TNSA (Target Normal Sheath Acceleration) proton source at GSI's Z6 experimental area. At consecutive stages a pulsed solenoid has been applied for beam transport and energy selection via chromatic focusing, as well as a radiofrequency cavity for energy compression of the bunch. This novel laser-driven proton beamline, representing a central experiment of the German national LIGHT collaboration (Laser Ion Generation, Handling and Transport), has been used to create collimated, intense proton bunches at 10 MeV with 2.7% energy spread from the laser-driven source. Also, the feasibility of phase focusing experiments with this setup has been shown and simulations predict peak currents of 10{sup 10} protons/ns at this energy level. Furthermore, first quantitative measurements on the spectral properties of the also present co-moving electrons from such a proton source could be performed and their influence on the protons within the solenoid observed. Finally, permanent magnetic quadrupoles as an alternative first ion collimation system have been investigated experimentally.

  14. The test beamline of the European Spallation Source – Instrumentation development and wavelength frame multiplication

    Energy Technology Data Exchange (ETDEWEB)

    Woracek, R., E-mail: robin.woracek@esss.se [European Spallation Source ESS ERIC, P.O. Box 176, SE-22100 Lund (Sweden); Hofmann, T.; Bulat, M. [Helmholtz-Zentrum Berlin für Materialien und Energie, Hahn-Meitner Platz 1, 14109 Berlin (Germany); Sales, M. [Technical University of Denmark, Fysikvej, 2800 Kgs. Lyngby (Denmark); Habicht, K. [Helmholtz-Zentrum Berlin für Materialien und Energie, Hahn-Meitner Platz 1, 14109 Berlin (Germany); Andersen, K. [European Spallation Source ESS ERIC, P.O. Box 176, SE-22100 Lund (Sweden); Strobl, M. [European Spallation Source ESS ERIC, P.O. Box 176, SE-22100 Lund (Sweden); Technical University of Denmark, Fysikvej, 2800 Kgs. Lyngby (Denmark)

    2016-12-11

    The European Spallation Source (ESS), scheduled to start operation in 2020, is aiming to deliver the most intense neutron beams for experimental research of any facility worldwide. Its long pulse time structure implies significant differences for instrumentation compared to other spallation sources which, in contrast, are all providing short neutron pulses. In order to enable the development of methods and technology adapted to this novel type of source well in advance of the first instruments being constructed at ESS, a test beamline (TBL) was designed and built at the BER II research reactor at Helmholtz-Zentrum Berlin (HZB). Operating the TBL shall provide valuable experience in order to allow for a smooth start of operations at ESS. The beamline is capable of mimicking the ESS pulse structure by a double chopper system and provides variable wavelength resolution as low as 0.5% over a wide wavelength band between 1.6 Å and 10 Å by a dedicated wavelength frame multiplication (WFM) chopper system. WFM is proposed for several ESS instruments to allow for flexible time-of-flight resolution. Hence, ESS will benefit from the TBL which offers unique possibilities for testing methods and components. This article describes the main capabilities of the instrument, its performance as experimentally verified during the commissioning, and its relevance to currently starting ESS instrumentation projects.

  15. Description and calibration beamline SEM/Ion Chamber Current Digitizer

    International Nuclear Information System (INIS)

    Schoo, D.

    1994-05-01

    This report discusses the following on beamline SEM/ion chamber current digitizers: Module description; testing and calibration; common setup procedures; summary of fault indications and associated causes; summary of input and output connections; SEM conversion constant table; ion chamber conversion constant table; hexadecimal to decimal conversion table; and schematic diagram

  16. The Nanoscience Beamline (I06) at Diamond Light Source

    International Nuclear Information System (INIS)

    Dhesi, S. S.; Cavill, S. A.; Potenza, A.; Marchetto, H.; Mott, R. A.; Steadman, P.; Peach, A.; Shepherd, E. L.; Ren, X.; Wagner, U. H.; Reininger, R.

    2010-01-01

    The Nanoscience beamline (I06) is one of seven Diamond Phase-I beamlines which has been operational since January 2007 delivering polarised soft x-rays, for a PhotoEmission Electron Microscope (PEEM) and branchline, in the energy range 80-2100 eV. The beamline is based on a collimated plane grating monochromator with sagittal focusing elements, utilising two APPLE II helical undulator sources, and has been designed for high flux density at the PEEM sample position. A ∼5 μm (σ) diameter beam is focussed onto the sample in the PEEM allowing a range of experiments using x-ray absorption spectroscopy (XAS), x-ray magnetic circular dichroism (XMCD) and x-ray magnetic linear dichroism (XMLD) as contrast mechanisms. The beamline is also equipped with a branchline housing a 6T superconducting magnet for XMCD and XMLD experiments. The magnet is designed to move on and off the branchline which allows a diverse range of experiments.

  17. Optical design study of the PEARL beamline at SLS

    Czech Academy of Sciences Publication Activity Database

    Oberta, Peter; Flechsig, U.; Muntwiler, M.; Quitmann, C.

    2011-01-01

    Roč. 635, č. 1 (2011), s. 116-120 ISSN 0168-9002 Institutional research plan: CEZ:AV0Z10100522 Keywords : PGM * beamline design * photo-emision Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.207, year: 2011

  18. Aberration analysis calculations for synchrotron radiation beamline design

    International Nuclear Information System (INIS)

    McKinney, W.R.; Howells, M.; Padmore, H.A.

    1997-09-01

    The application of ray deviation calculations based on aberration coefficients for a single optical surface for the design of beamline optical systems is reviewed. A systematic development is presented which allows insight into which aberration may be causing the rays to deviate from perfect focus. A new development allowing analytical calculation of line shape is presented

  19. Remote access and automation of SPring-8 MX beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Ueno, Go, E-mail: ueno@spring8.or.jp; Hikima, Takaaki; Yamashita, Keitaro; Hirata, Kunio; Yamamoto, Masaki [RIKEN SPring-8 Center, 1-1-1 Koto, Sayo-cho, Sayo-gun, Hyogo 679-5148 JAPAN (Japan); Hasegawa, Kazuya; Murakami, Hironori; Furukawa, Yukito; Mizuno, Nobuhiro; Kumasaka, Takashi [SPring-8/JASRI, 1-1-1 Koto, Sayo-cho, Sayo-gun, Hyogo 679-5198 JAPAN (Japan)

    2016-07-27

    At SPring-8 MX beamlines, a remote access system has been developed and started user operation in 2010. The system has been developed based on an automated data collection and data management architecture utilized for the confirmed scheme of SPring-8 mail-in data collection. Currently, further improvement to the remote access and automation which covers data processing and analysis are being developed.

  20. Beamline standard component designs for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Shu, D.; Barraza, J.; Brite, C.; Chang, J.; Sanchez, T.; Tcheskidov, V.; Kuzay, T.M.

    1994-01-01

    The Advanced Photon Source (APS) has initiated a design standardization and modularization activity for the APS synchrotron radiation beamline components. These standard components are included in components library, sub-components library and experimental station library. This paper briefly describes these standard components using both technical specifications and side view drawings

  1. Trichromatic concept at the SPring-8 RIKEN beamline I

    International Nuclear Information System (INIS)

    Yamamoto, Masaki; Kumasaka, Takashi; Ueki, Tatzuo

    1998-01-01

    At the SPring-8, RIKEN beamline I has been designed and developed for structural biology research by the Institute of Physical and Chemical Research (RIKEN). RIKEN beamline I consists of two experimental stations, protein crystallography (PX) and small-angle X-ray scattering (SAXS). Both experiments can be carried out simultaneously, with dichromatic synchrotron radiation emitted from two coaxial undulators with vertical polarization. The branched beams are generated by a transparent diamond crystal. With synchrotron radiation, the multi-wavelength anomalous diffraction (MAD) method, which gives phases from a single anomalous scatterer, has been developed. Anomalous scattering contributes a small portion of diffraction intensity so that the accuracy of intensity data is definitely important. The PX branch of RIKEN beamline I has been designed based on a 'trichromatic concept' to optimize for the MAD data collection. This concept is that three kinds of intensity data sets with three different wavelengths are taken quasi-simultaneously for the single protein crystal without changing any setting by 'trichromator'. The main feature of this concept is to minimize systematic errors in the measurements of anomalous diffraction for the MAD method. The construction of RIKEN beamline I had been progressed satisfactorily until June 1997. The initial commissioning successfully provided the three different monochromatized undulator beams were successfully observed on the phosphor screen, which located at the near end of the trichromator. (author)

  2. High pressure XAFS experiments at the XAFS beamline, INDUS-2

    International Nuclear Information System (INIS)

    Ramanan, Nitya; Lahiri, Debdutta; Garg, Nandini; Sharma, Surinder M.; Bhattacharyya, D.; Jha, S.N.; Sahoo, N.K.

    2011-01-01

    The dispersive EXAFS beamline at the INDUS-2 synchrotron source, RRCAT, Indore uses a bent Si (111) crystal as a dispersive-cum-focusing element and a position sensitive CCD detector to enable instantaneous measurement of the whole EXAFS spectrum around the absorption edge of a particular atom. One of the proposed activities with this beamline is the characterization of amorphous materials under high pressure. Polychromator-based beamline is ideal for high pressure studies using Diamond Anvil Cell (DAC) with ∼ 50 μm sample size. Larger spot size would give rise to unwanted diffraction peaks from diamond, superimposed on the XAFS data. Micro-focusing by polychromator crystal and absence of its mechanical movement (unlike monochromator-based scanning-mode beamlines), during data collection, lead to required focal spot stability for DAC experiments. Currently, the theoretically determined spot size (Horizontal x vertical) varies between 17 x 137 μm and 37 x 142 μm for the X-ray energy range 5 keV-20 keV. To reduce the vertical spot size to <50 μm, we have designed an additional focusing mirror between the polychromator and sample position. The mirror, fabricated at SESO, France will be installed shortly. Meanwhile, we have carried out preliminary XAFS experiments on Sr-compounds at ∼16 keV, under ambient conditions and inside diamond anvil cell, in order to assess the signal intensity and quality. We have obtained reasonably good signal. (author)

  3. Construction and maintenance of SUNY facilities at the National Synchrotron Light Source. Progress report, 1 July 1983-1 July 1984. Final report

    International Nuclear Information System (INIS)

    Bigeleisen, J.

    1984-01-01

    Research reported includes beamline facilities, X-21 beamline update, SUNY-PRT participation in the design and commissioning of the CHESS crystallography facility, surface physics, material and structure studies using EXAFS, x-ray standing wave studies of surfaces and interfaces, and surface diffraction of adsorbed polyatomic molecules

  4. LNLS soft x-ray spectroscopy (SXS) beamline

    International Nuclear Information System (INIS)

    Tolentino, Helio; Rocha, Milton C.; Tamura, Edilson; Cezar, Julio C.; Vicentin, Flavio C.; Giles, Carlos; Compagnon-Cailhol, Valerie; Abbate, Miguel; Cruz, Daniela Z.N.; Mocellin, Alexandra

    1996-01-01

    The Soft X-ray Spectroscopy beamline will be dedicated to the study of structural, electronic and magnetic properties of materials by using photoabsorption and photoemission techniques, X-ray dischroism will be used to study magnetism of transition metals and rare earths compounds. This beamline is one of the first seven beamlines which were decided to start operation along with the storage ring. Part of the beamline - mostly importations - has been granted by fundings from the state of Sao Paulo (Fapesp). The electron energy analyser came through EEC from a cooperation with a French group at LURE. All components of the beamline are either constructed or bougth and being mounted at the storage ring. The monochromator has already been commissioned under UHV, attaining the specification of 5x10 -9 Torr. To cover the whole energy range, from 800 eV up to 4000 eV, many crystals have been bought, cut and tested. The mirror has been specified in order to focus the source in both directions. Simulations using the Shadow code (source simulation and ray tracing technique) were performed in order to optimize the performance of the optics. We expert to focus 10 mrad down to a spot of 3.0x1.5 mm 2 . The mirror chamber has already been constructed and commissioned under UHV conditions (pressure -9 Torr). The mechanics (mechanical feedthroughs, stability, etc..) has been tested using an X-ray source and has been approved. The experimental chamber has already been used for photoemission experiments using a conventional AL/Mg X-ray source. Many results have been obtained and two master thesis have been performed using this set-up. (author)

  5. The INE-Beamline for actinide science at ANKA

    Science.gov (United States)

    Rothe, J.; Butorin, S.; Dardenne, K.; Denecke, M. A.; Kienzler, B.; Löble, M.; Metz, V.; Seibert, A.; Steppert, M.; Vitova, T.; Walther, C.; Geckeis, H.

    2012-04-01

    Since its inauguration in 2005, the INE-Beamline for actinide research at the synchrotron source ANKA (KIT North Campus) provides dedicated instrumentation for x-ray spectroscopic characterization of actinide samples and other radioactive materials. R&D work at the beamline focuses on various aspects of nuclear waste disposal within INE's mission to provide the scientific basis for assessing long-term safety of a final nuclear waste repository. The INE-Beamline is accessible for the actinide and radiochemistry community through the ANKA proposal system and the European Union Integrated Infrastructure Initiative ACTINET-I3. Experiments with activities up to 1 × 10+6 times the European exemption limit are feasible within a safe but flexible containment concept. Measurements with monochromatic radiation are performed at photon energies varying between ˜2.1 keV (P K-edge) and ˜25 keV (Pd K-edge), including the lanthanide L-edges and the actinide M- and L3-edges up to Cf. The close proximity of the INE-Beamline to INE controlled area labs offers infrastructure unique in Europe for the spectroscopic and microscopic characterization of actinide samples. The modular beamline design enables sufficient flexibility to adapt sample environments and detection systems to many scientific questions. The well-established bulk techniques x-ray absorption fine structure (XAFS) spectroscopy in transmission and fluorescence mode have been augmented by advanced methods using a microfocused beam, including (confocal) XAFS/x-ray fluorescence detection and a combination of (micro-)XAFS and (micro-)x-ray diffraction. Additional instrumentation for high energy-resolution x-ray emission spectroscopy has been successfully developed and tested.

  6. The INE-Beamline for actinide science at ANKA

    International Nuclear Information System (INIS)

    Rothe, J.; Dardenne, K.; Denecke, M. A.; Kienzler, B.; Loeble, M.; Metz, V.; Steppert, M.; Vitova, T.; Geckeis, H.; Butorin, S.; Seibert, A.; Walther, C.

    2012-01-01

    Since its inauguration in 2005, the INE-Beamline for actinide research at the synchrotron source ANKA (KIT North Campus) provides dedicated instrumentation for x-ray spectroscopic characterization of actinide samples and other radioactive materials. R and D work at the beamline focuses on various aspects of nuclear waste disposal within INE's mission to provide the scientific basis for assessing long-term safety of a final nuclear waste repository. The INE-Beamline is accessible for the actinide and radiochemistry community through the ANKA proposal system and the European Union Integrated Infrastructure Initiative ACTINET-I3. Experiments with activities up to 1 x 10 +6 times the European exemption limit are feasible within a safe but flexible containment concept. Measurements with monochromatic radiation are performed at photon energies varying between ∼2.1 keV (P K-edge) and ∼25 keV (Pd K-edge), including the lanthanide L-edges and the actinide M- and L3-edges up to Cf. The close proximity of the INE-Beamline to INE controlled area labs offers infrastructure unique in Europe for the spectroscopic and microscopic characterization of actinide samples. The modular beamline design enables sufficient flexibility to adapt sample environments and detection systems to many scientific questions. The well-established bulk techniques x-ray absorption fine structure (XAFS) spectroscopy in transmission and fluorescence mode have been augmented by advanced methods using a microfocused beam, including (confocal) XAFS/x-ray fluorescence detection and a combination of (micro-)XAFS and (micro-)x-ray diffraction. Additional instrumentation for high energy-resolution x-ray emission spectroscopy has been successfully developed and tested.

  7. Beamline 9.3.2 - a high-resolution, bend-magnet beamline with circular polarization capability

    Energy Technology Data Exchange (ETDEWEB)

    Moler, E.J.; Hussain, Z.; Howells, M.R. [Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    Beamline 9.3.2 is a high resolution, SGM beamline on an ALS bending magnet with access to photon energies from 30-1500 eV. Features include circular polarization capability, a rotating chamber platform that allows switching between experiments without breaking vacuum, an active feedback system that keeps the beam centered on the entrance slit of the monochromator, and a bendable refocusing mirror. The beamline optics consist of horizontally and vertically focussing mirrors, a Spherical Grating Monochromator (SGM) with movable entrance and exit slits, and a bendable refocussing mirror. In addition, a movable aperature has been installed just upstream of the vertically focussing mirror which can select the x-rays above or below the plane of the synchrotron storage ring, allowing the user to select circularly or linearly polarized light. Circularly polarized x-rays are used to study the magnetic properties of materials. Beamline 9.3.2 can supply left and right circularly polarized x-rays by a computer controlled aperture which may be placed above or below the plane of the synchrotron storage ring. The degree of linear and circular polarization has been measured and calibrated.

  8. A beamline for high-pressure studies at the Advanced Light Source with a superconducting bending magnet as the source.

    Science.gov (United States)

    Kunz, Martin; MacDowell, Alastair A; Caldwell, Wendel A; Cambie, Daniella; Celestre, Richard S; Domning, Edward E; Duarte, Robert M; Gleason, Arianna E; Glossinger, James M; Kelez, Nicholas; Plate, David W; Yu, Tony; Zaug, Joeseph M; Padmore, Howard A; Jeanloz, Raymond; Alivisatos, A Paul; Clark, Simon M

    2005-09-01

    A new facility for high-pressure diffraction and spectroscopy using diamond anvil high-pressure cells has been built at the Advanced Light Source on beamline 12.2.2. This beamline benefits from the hard X-radiation generated by a 6 T superconducting bending magnet (superbend). Useful X-ray flux is available between 5 keV and 35 keV. The radiation is transferred from the superbend to the experimental enclosure by the brightness-preserving optics of the beamline. These optics are comprised of a plane parabola collimating mirror, followed by a Kohzu monochromator vessel with Si(111) crystals (E/DeltaE approximately equal 7000) and W/B4C multilayers (E/DeltaE approximately equal 100), and then a toroidal focusing mirror with variable focusing distance. The experimental enclosure contains an automated beam-positioning system, a set of slits, ion chambers, the sample positioning goniometry and area detector (CCD or image-plate detector). Future developments aim at the installation of a second endstation dedicated to in situ laser heating and a dedicated high-pressure single-crystal station, applying both monochromatic and polychromatic techniques.

  9. Monte Carlo simulation for the transport beamline

    Energy Technology Data Exchange (ETDEWEB)

    Romano, F.; Cuttone, G.; Jia, S. B.; Varisano, A. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania (Italy); Attili, A.; Marchetto, F.; Russo, G. [INFN, Sezione di Torino, Via P.Giuria, 1 10125 Torino (Italy); Cirrone, G. A. P.; Schillaci, F.; Scuderi, V. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy and Institute of Physics Czech Academy of Science, ELI-Beamlines project, Na Slovance 2, Prague (Czech Republic); Carpinelli, M. [INFN Sezione di Cagliari, c/o Dipartimento di Fisica, Università di Cagliari, Cagliari (Italy); Tramontana, A. [INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy and Università di Catania, Dipartimento di Fisica e Astronomia, Via S. Sofia 64, Catania (Italy)

    2013-07-26

    In the framework of the ELIMED project, Monte Carlo (MC) simulations are widely used to study the physical transport of charged particles generated by laser-target interactions and to preliminarily evaluate fluence and dose distributions. An energy selection system and the experimental setup for the TARANIS laser facility in Belfast (UK) have been already simulated with the GEANT4 (GEometry ANd Tracking) MC toolkit. Preliminary results are reported here. Future developments are planned to implement a MC based 3D treatment planning in order to optimize shots number and dose delivery.

  10. Monte Carlo simulation for the transport beamline

    International Nuclear Information System (INIS)

    Romano, F.; Cuttone, G.; Jia, S. B.; Varisano, A.; Attili, A.; Marchetto, F.; Russo, G.; Cirrone, G. A. P.; Schillaci, F.; Scuderi, V.; Carpinelli, M.; Tramontana, A.

    2013-01-01

    In the framework of the ELIMED project, Monte Carlo (MC) simulations are widely used to study the physical transport of charged particles generated by laser-target interactions and to preliminarily evaluate fluence and dose distributions. An energy selection system and the experimental setup for the TARANIS laser facility in Belfast (UK) have been already simulated with the GEANT4 (GEometry ANd Tracking) MC toolkit. Preliminary results are reported here. Future developments are planned to implement a MC based 3D treatment planning in order to optimize shots number and dose delivery

  11. The Project for the High Energy Materials Science Beamline at Petra III

    International Nuclear Information System (INIS)

    Martins, R. V.; Lippmann, T.; Beckmann, F.; Schreyer, A.

    2007-01-01

    The high energy materials science beamline will be among the first fourteen beamlines planned to be operational in 2009 at the new third generation synchrotron light source Petra III at DESY, Germany. The operation and funding of this beamline is assured by GKSS. 70% of the beamline will be dedicated to materials science. The remaining 30% are reserved for physics and are covered by DESY. The materials science activities will be concentrating on three intersecting topics which are industrial, applied, and fundamental research. The beamline will combine three main features: Firstly, the high flux, fast data acquisition systems, and the beamline infrastructure will allow carrying out complex and highly dynamic in-situ experiments. Secondly, a high flexibility in beam shaping will be available, fully exploiting the high brilliance of the source. Thirdly, the beamline will provide the possibility to merge in one experiment different analytical techniques such as diffraction and tomography

  12. ELIMED: MEDICAL APPLICATION AT ELI-BEAMLINES. STATUS OF THE COLLABORATION AND FIRST RESULTS

    Directory of Open Access Journals (Sweden)

    Francesco Schillaci

    2014-08-01

    Full Text Available ELI-Beamlines is one of the four pillars of the ELI (Extreme Light Infrastructure pan-European project. It will be an ultrahigh-intensity, high repetition-rate, femtosecond laser facility whose main goal is to generate and apply high-brightness X-ray sources and accelerated charged particles. In particular, medical applications are treated by the ELIMED task force, which has been launched by collaboration between ELI and INFN researchers. ELIMED aims to demonstrate the clinical applicability of laser accelerated ions. In this article, the state of the ELIMED project and the first scientific results are reported. The design and realisation of a preliminary beam handling system and of an advanced spectrometer for diagnostics of high energy (multi-MeV laser-accelerated ion beams will also be briefly presented.

  13. MONO: A program to calculate synchrotron beamline monochromator throughputs

    International Nuclear Information System (INIS)

    Chapman, D.

    1989-01-01

    A set of Fortran programs have been developed to calculate the expected throughput of x-ray monochromators with a filtered synchrotron source and is applicable to bending magnet and wiggler beamlines. These programs calculate the normalized throughput and filtered synchrotron spectrum passed by multiple element, flat un- focussed monochromator crystals of the Bragg or Laue type as a function of incident beam divergence, energy and polarization. The reflected and transmitted beam of each crystal is calculated using the dynamical theory of diffraction. Multiple crystal arrangements in the dispersive and non-dispersive mode are allowed as well as crystal asymmetry and energy or angle offsets. Filters or windows of arbitrary elemental composition may be used to filter the incident synchrotron beam. This program should be useful to predict the intensities available from many beamline configurations as well as assist in the design of new monochromator and analyzer systems. 6 refs., 3 figs

  14. Indus-I beamlines for condensed matter physics

    International Nuclear Information System (INIS)

    Nandedkar, R.V.

    2001-01-01

    Full text: A 450 MeV electron storage ring Indus-I is now operational. This storage ring gives synchrotron radiation in soft x-ray vacuum ultra violet (VUV) and to visible region. On this storage ring six beamlines are now being set up for atomic and molecular spectroscopy experiments, solid state spectroscopy experiments and soft and VUV reflectivity experiments. In this talk, present status of beamlines which condense matter physicists will be interested in will be given along with some commissioning experiments. These beam lines are based on a toroidal grating monochromators in the range 40 - 1000 A with moderate energy resolution. Some experiments which can be conducted using these beam lines will be discussed

  15. Intensity interferometry at the X13A undulator beamline

    International Nuclear Information System (INIS)

    Gluskin, E.; McNulty, I.; Yang, L.; Randall, K.J.; Johnson, E.D.

    1993-01-01

    We are constructing a soft x-ray intensity interferometer and an undulator based beamline to demonstrate intensity interferometry in the x-ray region. The 10-period soft x-ray undulator at the NSLS provides the necessary coherent flux; the X13A beamline is designed to preserve the spatial coherence of the bright x-ray beam and provide sufficient temporal coherence using a horizontally deflecting spherical grating monochromator. Using the interferometer, which consists of an array of small slits, a wedge-shaped beamsplitter and two fast microchannel plate detectors, we expect to measure the spatial coherence of the undulator beam and therefore the size of the source in the vertical plane. Details of the bean-dine design and the interferometer experiment are discussed

  16. Magnetic shielding tests for MFTF-B neutral beamlines

    International Nuclear Information System (INIS)

    Kerns, J.; Fabyan, J.; Wood, R.; Koger, P.

    1983-01-01

    A test program to determine the effectiveness of various magnetic shielding designs for MFTF-B beamlines was established at Lawrence Livermore National Laboratory (LLNL). The proposed one-tenth-scale shielding-design models were tested in a uniform field produced by a Helmholtz coil pair. A similar technique was used for the MFTF source-injector assemblies, and the model test results were confirmed during the Technology Demonstration in 1982. The results of these tests on shielding designs for MFTF-B had an impact on the beamline design for MFTF-B. The iron-core magnet and finger assembly originally proposed were replaced by a simple, air-core, race-track-coil, bending magnet. Only the source injector needs to be magnetically shielded from the fields of approximately 400 gauss

  17. Beam Position Monitoring in the CSU Accelerator Facility

    Science.gov (United States)

    Einstein, Joshua; Vankeuren, Max; Watras, Stephen

    2014-03-01

    A Beam Position Monitoring (BPM) system is an integral part of an accelerator beamline, and modern accelerators can take advantage of newer technologies and designs when creating a BPM system. The Colorado State University (CSU) Accelerator Facility will include four stripline detectors mounted around the beamline, a low-noise analog front-end, and digitization and interface circuitry. The design will support a sampling rate greater than 10 Hz and sub-100 μm accuracy.

  18. DARHT-II Downstream Transport Beamline

    International Nuclear Information System (INIS)

    Westenskow, G A; Bertolini, L R; Duffy, P T; Paul, A C

    2001-01-01

    This paper describes the mechanical design of the downstream beam transport line for the second axis of the Dual Axis Radiographic Hydrodynamic Test (DARHT II) Facility. The DARHT-II project is a collaboration between LANL, LBNL and LLNL. DARHT II is a 18.4-MeV, 2000-Amperes, 2-(micro)sec linear induction accelerator designed to generate short bursts of x-rays for the purpose of radiographing dense objects. The downstream beam transport line is approximately 22-meter long region extending from the end of the accelerator to the bremsstrahlung target. Within this proposed transport line there are 12 conventional solenoid, quadrupole and dipole magnets; as well as several specialty magnets, which transport and focus the beam to the target and to the beam dumps. There are two high power beam dumps, which are designed to absorb 80-kJ per pulse during accelerator start-up and operation. Aspects of the mechanical design of these elements are presented

  19. First transmission of electrons and ions through the KATRIN beamline

    Czech Academy of Sciences Publication Activity Database

    Arenz, M.; Dragoun, Otokar; Kovalík, Alojz; Lebeda, Ondřej; Ryšavý, Miloš; Sentkerestiová, Jana; Suchopár, Martin; Vénos, Drahoslav

    2018-01-01

    Roč. 13, č. 4 (2018), č. článku P04020. ISSN 1748-0221 R&D Projects: GA MŠk LM2015056; GA MŠk LTT18021 Institutional support: RVO:61389005 Keywords : ion sources * electron beam * detector control systems * beam-line instrumentation * spectrometers Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders OBOR OECD: Nuclear physics Impact factor: 1.220, year: 2016

  20. Measurement of intensity distribution of CSR in LEBRA PXR beamline

    International Nuclear Information System (INIS)

    Nakao, Keisuke; Sakai, Takeshi; Hayakawa, Ken; Tanaka, Toshinari; Hayakawa, Yasushi; Nogami, Kyoko; Inagaki, Manabu; Sei, Norihiro

    2014-01-01

    Last year, the intensity of Coherent Synchrotron Radiation (CSR) in LEBRA PXR beamline was measured. As a result, it turned out that the intensity of CSR was stronger than anticipation. It is suggested that Coherent Edge Radiation (CER) is mixed with CSR. Then, in order to confirm whether CER is contained, the intensity distribution of CSR was measured. The result of the experiment is reported in this paper. (author)

  1. Surface science station of the infrared beamline at SPring-8

    International Nuclear Information System (INIS)

    Sakurai, M.; Moriwaki, T.; Kimura, H.; Nishida, S.; Nanba, T.

    2001-01-01

    An experimental station for surface science has been constructed at the infrared beamline (BL43IR) of SPring-8, Japan. The station utilizes synchrotron radiation in the energy range of 100-20000 cm -1 to perform infrared reflection absorption spectroscopy (IRAS) of surfaces. It consists of an experimental section, a preparation chamber, gas handling equipment and a pair of focusing optics. In situ observation of vibrational spectra is possible using both IRAS and high-resolution electron energy loss spectroscopy

  2. Successful test of SPS-to-LHC beamline

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    On 23 October there was great excitement in the Prevessin control room when, on the first attempt, a beam passed over 2.5 km down the new SPS-to-LHC transfer line, TI8, to within a few metres of the LHC tunnel. Members of the AB, AT and TS departments involved in the beamline and its test, celebrate their success with the Director General, Robert Aymar, and the LHC Project Leader, Lyn Evans.

  3. Successful test of SPS-to-LHC beamline

    CERN Multimedia

    2004-01-01

    On 23 October there was great excitement in the Prevessin control room when, on the first attempt, a beam passed over 2.5 km down the new SPS-to-LHC transfer line, TI8, to within a few metres of the LHC tunnel. Above: members of the AB, AT and TS departments involved in the beamline and its test, celebrate their success with the Director General, Robert Aymar, and the LHC Project Leader, Lyn Evans.

  4. Pulsed beam tests at the SANAEM RFQ beamline

    Science.gov (United States)

    Turemen, G.; Akgun, Y.; Alacakir, A.; Kilic, I.; Yasatekin, B.; Ergenlik, E.; Ogur, S.; Sunar, E.; Yildiz, V.; Ahiska, F.; Cicek, E.; Unel, G.

    2017-07-01

    A proton beamline consisting of an inductively coupled plasma (ICP) source, two solenoid magnets, two steerer magnets and a radio frequency quadrupole (RFQ) is developed at the Turkish Atomic Energy Authority’s (TAEA) Saraykoy Nuclear Research and Training Center (SNRTC-SANAEM) in Ankara. In Q4 of 2016, the RFQ was installed in the beamline. The high power tests of the RF power supply and the RF transmission line were done successfully. The high power RF conditioning of the RFQ was performed recently. The 13.56 MHz ICP source was tested in two different conditions, CW and pulsed. The characterization of the proton beam was done with ACCTs, Faraday cups and a pepper-pot emittance meter. Beam transverse emittance was measured in between the two solenoids of the LEBT. The measured beam is then reconstructed at the entrance of the RFQ by using computer simulations to determine the optimum solenoid currents for acceptance matching of the beam. This paper will introduce the pulsed beam test results at the SANAEM RFQ beamline. In addition, the high power RF conditioning of the RFQ will be discussed.

  5. Performance of a novel VUV bending magnet beamline

    CERN Document Server

    Song, Y F; Hsieh, T F; Huang, L R; Chung, S C; Cheng, N F; Hsiung, G Y; Wang, D J; Chen, C T; Tsang, K L

    2001-01-01

    A novel high resolution, high flux bending magnet beamline with an energy range from 5 to 40 eV has been constructed at SRRC. This Dragon-like beamline, which horizontally collects 50 mrad of synchrotron radiation from a bending magnet source, uses four cylindrical gratings with an included angle of 140 deg. and a movable curved exit slit. The average photon flux with an energy resolving power of 1000 is about 2x10 sup 1 sup 2 photons/s, which is among the highest of all existing VUV bending magnet beamlines. An energy resolving power of 24,000 at 6.8 eV has been obtained from the Schumann-Runge bands (B sup 3 limit construction operator in a limit construction/sum L: summation operator operator End lower limit of a limit construction u lower limit End limit End sup - /leftarrow/gets A: =leftward arrow X sup 3 limit construction operator in a limit construction/sum L: summation operator operator End lower limit of a limit construction g lower limit End limit End sup -) absorption spectra of O sub 2 gas. A pho...

  6. ADLIB: A simple database framework for beamline codes

    International Nuclear Information System (INIS)

    Mottershead, C.T.

    1993-01-01

    There are many well developed codes available for beamline design and analysis. A significant fraction of each of these codes is devoted to processing its own unique input language for describing the problem. None of these large, complex, and powerful codes does everything. Adding a new bit of specialized physics can be a difficult task whose successful completion makes the code even larger and more complex. This paper describes an attempt to move in the opposite direction, toward a family of small, simple, single purpose physics and utility modules, linked by an open, portable, public domain database framework. These small specialized physics codes begin with the beamline parameters already loaded in the database, and accessible via the handful of subroutines that constitute ADLIB. Such codes are easier to write, and inherently organized in a manner suitable for incorporation in model based control system algorithms. Examples include programs for analyzing beamline misalignment sensitivities, for simulating and fitting beam steering data, and for translating among MARYLIE, TRANSPORT, and TRACE3D formats

  7. The vacuum interlock system for the PETRA III beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Degenhardt, Markus; Hahn, Ulrich; Hesse, Mathias; Schulte-Schrepping, Horst [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2008-07-01

    The storage ring PETRA at DESY in Hamburg is being reconstructed into the third generation source for synchrotron radiation, PETRA III. The up to 100 m long beamlines are large UHV-systems that guide the synchrotron radiation from the storage ring to the experiments. Each beamline will be equipped with a vacuum interlock system to ensure the safe operation of the vacuum components. In particular the task of the vacuum interlock is to prevent faulty operations that can cause a ventilation of the vacuum system or a damage of vacuum components by the high power synchrotron radiation beam. The interlock system will be implemented as a PLC that is connected to a distributed input/output layer via a field bus system. As a specialty, the PLC will be realised as a soft-PLC running on a PC with a real time windows operating system. Another specialty is the visualisation and remote control of the vacuum interlock system by means of a website. At the beamline the interlock will be operated via a touch panel that displays the visualisation website. Additionally, the interlock can be remotely operated from any location by opening the visualisation website with a browser. The interlock is protected against unauthorised operation by a login page. All relevant interlock data will be fed into the existing network-based archive system.

  8. Ultrabroadband terahertz source and beamline based on coherent transition radiation

    Directory of Open Access Journals (Sweden)

    S. Casalbuoni

    2009-03-01

    Full Text Available Coherent transition radiation (CTR in the THz regime is an important diagnostic tool for analyzing the temporal structure of the ultrashort electron bunches needed in ultraviolet and x-ray free-electron lasers. It is also a powerful source of such radiation, covering an exceptionally broad frequency range from about 200 GHz to 100 THz. At the soft x-ray free-electron laser FLASH we have installed a beam transport channel for transition radiation (TR with the intention to guide a large fraction of the radiation to a laboratory outside the accelerator tunnel. The radiation is produced on a screen inside the ultrahigh vacuum beam pipe of the linac, coupled out through a diamond window and transported to the laboratory through an evacuated tube equipped with five focusing and four plane mirrors. The design of the beamline has been based on a thorough analysis of the generation of TR on metallic screens of limited size. The optical propagation of the radiation has been computed taking into account the effects of near-field (Fresnel diffraction. The theoretical description of the TR source is presented in the first part of the paper, while the design principles and the technical layout of the beamline are described in the second part. First experimental results demonstrate that the CTR beamline covers the specified frequency range and preserves the narrow time structure of CTR pulses emitted by short electron bunches.

  9. Nanotomography endstation at the P05 beamline: Status and perspectives

    Science.gov (United States)

    Greving, I.; Ogurreck, M.; Marschall, F.; Last, A.; Wilde, F.; Dose, T.; Burmester, H.; Lottermoser, L.; Müller, M.; David, C.; Beckmann, F.

    2017-06-01

    The Imaging Beamline IBL/P05 at the DESY storage ring PETRA III, operated by the Helmholtz-Zentrum Geesthacht, has two dedicated endstations optimized for micro- and nanotomography experiments [1-3]. Here we present the status of the nanotomography endstation, highlight the latest instrumentation upgrades and present first experimental results. In particular in materials science, where structures with ceramics or metallic materials are of interest, X-ray energies of 15 keV and above are required even for sample sizes of several 10 μm in diameter. The P05 imaging beamline is dedicated to materials science and is designed to allow for imaging applications with X-ray energies of 10 to 50 keV. In addition to the full field X-ray microscopy setup, the layout of the nanotomography endstation allows switching to cone-beam configuration. Kinematics for X-ray optics like compound refractive lenses (CRLs), Fresnel zone plates (FZP) or beam-shaping optics are implemented and the installation of a Kirkpatrick Baez-mirror (KB mirror) system is foreseen at a later stage of the beamline development. Altogether this leads to a high flexibility of the nanotomography setup such that the instrument can be tailored to the specific experimental requirements of a range of sample systems.

  10. Performance specifications for proton medical facility

    Energy Technology Data Exchange (ETDEWEB)

    Chu, W.T.; Staples, J.W.; Ludewigt, B.A.; Renner, T.R.; Singh, R.P.; Nyman, M.A.; Collier, J.M.; Daftari, I.K.; Petti, P.L.; Alonso, J.R. [Lawrence Berkeley Lab., CA (United States); Kubo, H.; Verhey, L.J. [University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine; Castro, J.R. [Lawrence Berkeley Lab., CA (United States)]|[University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine

    1993-03-01

    Performance specifications of technical components of a modern proton radiotherapy facility are presented. The technical items specified include: the accelerator; the beam transport system including rotating gantry; the treatment beamline systems including beam scattering, beam scanning, and dosimetric instrumentation; and an integrated treatment and accelerator control system. Also included are treatment ancillary facilities such as diagnostic tools, patient positioning and alignment devices, and treatment planning systems. The facility specified will accommodate beam scanning enabling the three-dimensional conformal therapy deliver .

  11. Conceptual design of NBI beamline for VEST plasma heating

    Energy Technology Data Exchange (ETDEWEB)

    Kim, T.S., E-mail: tskim@kaeri.re.kr; In, S.R.; Jeong, S.H.; Park, M.; Chang, D.H.; Jung, B.K.; Lee, K.W.

    2016-11-01

    Highlights: • VEST NBI injector is conceptually designed to support further VEST plasma experiment. • VEST NBI injector composed of 2 sets of 20 keV/25A magnetic cusp type bucket ion source, neutralizer ducts, electrostatic ion dumps, NB vessel with cryopump, and rotating calorimerter. • The vacuum vessel of the beamline is divided into two parts for high injection efficiency and different direction (co- and counter-current) of neutral beam injection. • An ion source for the VEST NBI system was also designed to deliver neutral hydrogen beams with a power of 0.3 MW. The plasma generator of the VEST NB ion source has modified TFTR bucket multi-cusp chamber. The plasma generator has twelve hair-pin shaped tungsten filaments used as a cathode and an arc chamber including a bucket and an electron dump which serve as anode. The accelerator system consists of three grids, each having extraction area of 100 mm × 320 mm and 64 shaped slits of 3 mm spacing. • The preliminary structure design and the layout of the main components of the injector have been completed. Simulation and calculation for optimization of the NB beamline design results prove that the parameters of ion source, neutralization efficiency (76%:95% equilibrium neutralization efficiency), and beam power transmission efficiency (higher than 90%) are in agreement with design targets of the VEST NB beamline. • This VEST NBI system will provide a neutral beam of ∼0.6 MW for both heating and current drive in torus plasma. - Abstract: A 10 m s-pulsed NBI (Neutral Beam Injection) system for VEST (Versatile Experiment Spherical Torus) plasma heating is designed to provide a beam power of more than 0.6 MW with 20 keV H° neutrals. The VEST NBI injector is composed of 2 sets of 20 keV/25A magnetic cusp type bucket ion source, neutralizer ducts, residual ion dump, NB vessel with a cryopump, and rotating calorimeter. The position and size of these beamline components are roughly determined with geometric

  12. Conceptual design of NBI beamline for VEST plasma heating

    International Nuclear Information System (INIS)

    Kim, T.S.; In, S.R.; Jeong, S.H.; Park, M.; Chang, D.H.; Jung, B.K.; Lee, K.W.

    2016-01-01

    Highlights: • VEST NBI injector is conceptually designed to support further VEST plasma experiment. • VEST NBI injector composed of 2 sets of 20 keV/25A magnetic cusp type bucket ion source, neutralizer ducts, electrostatic ion dumps, NB vessel with cryopump, and rotating calorimerter. • The vacuum vessel of the beamline is divided into two parts for high injection efficiency and different direction (co- and counter-current) of neutral beam injection. • An ion source for the VEST NBI system was also designed to deliver neutral hydrogen beams with a power of 0.3 MW. The plasma generator of the VEST NB ion source has modified TFTR bucket multi-cusp chamber. The plasma generator has twelve hair-pin shaped tungsten filaments used as a cathode and an arc chamber including a bucket and an electron dump which serve as anode. The accelerator system consists of three grids, each having extraction area of 100 mm × 320 mm and 64 shaped slits of 3 mm spacing. • The preliminary structure design and the layout of the main components of the injector have been completed. Simulation and calculation for optimization of the NB beamline design results prove that the parameters of ion source, neutralization efficiency (76%:95% equilibrium neutralization efficiency), and beam power transmission efficiency (higher than 90%) are in agreement with design targets of the VEST NB beamline. • This VEST NBI system will provide a neutral beam of ∼0.6 MW for both heating and current drive in torus plasma. - Abstract: A 10 m s-pulsed NBI (Neutral Beam Injection) system for VEST (Versatile Experiment Spherical Torus) plasma heating is designed to provide a beam power of more than 0.6 MW with 20 keV H° neutrals. The VEST NBI injector is composed of 2 sets of 20 keV/25A magnetic cusp type bucket ion source, neutralizer ducts, residual ion dump, NB vessel with a cryopump, and rotating calorimeter. The position and size of these beamline components are roughly determined with geometric

  13. New synchrotron radiation facility project. Panel on new synchrotron radiation facility project

    CERN Document Server

    Sato, S; Kimura, Y

    2003-01-01

    The project for constructing a new synchrotron radiation facility dedicated to the science in VUV (or EUV) and Soft X-ray (SX) region has been discussed for these two years at the Panel on New Synchrotron Radiation Facility Project. The Panel together with the Accelerator Design Working Group (WG), Beamline Design WG and Research Program WG suggested to the Ministry of Education, Science, Culture and Sports the construction of a 1.8 GeV electron storage ring suitable for 'Top-Up' operation and beamlines and monochromators designed for undulator radiation. The scientific programs proposed by nationwide scientists are summarized with their requirements of the characteristics of the beam. (author)

  14. Petit-exposure at neutrino beamline (PEANUT)

    International Nuclear Information System (INIS)

    Niwa, K.

    2005-01-01

    The advantages of using nuclear emulsion as a particle detector are well known. The high resolution of emulsion has made it a medium of choice for a number of applications where the required spatial and angular resolution are paramount and its limitations due to the lack of timing information are less important. Emulsions are commonly used as cosmic ray detectors and have found applications in high energy experiments for detecting short lived particles such as charm, beauty and tau. The addition of electronic detectors to emulsion experiments solved the problem of the lack of timing information in the emulsion, but it was the development of automatic scanning machines that revolutionized the use of these hybrid detectors, making them capable of performing even in high rate environments. Most recently, The DONuT experiment (FNAL-E872), used a hybrid emulsion spectrometer to make the first direct observation of tau neutrino interactions [1]. The CNGS facility is being constructed to deliver a ν μ beam from the CERN SPS to the Gran Sasso Laboratory. Since it is believed that ν μ (leftrightarrow) ν τ oscillations explain the observed atmospheric ν μ deficit, the CNGS beam, coupled with a detector capable of observing τ appearance is an important experiment in the context of the world wide effort to determine the neutrino mass mixing matrix. The OPERA detector has been optimized to detect a significant sample of ν τ interactions by the subsequent observation of τ production and decay [2]. The OPERA target is a massive emulsion detector made in a sandwich structure of lead plates and layers of nuclear emulsion. For historical reasons this arrangement has been called an Emulsion Cloud Chamber or ECC. The ECC concept, which has many advantages over the use of bulk emulsion, has been used in the DONuT experiment. The ECC detector is capable of measuring all of the tracks, not due to nuclear fragments, coming from the primary neutrino interaction vertex, with

  15. I20; the Versatile X-ray Absorption spectroscopy beamline at Diamond Light Source

    International Nuclear Information System (INIS)

    Diaz-Moreno, S; Hayama, S; Amboage, M; Freeman, A; Sutter, J; Duller, G

    2009-01-01

    The Versatile Spectroscopy beamline at Diamond Light Source, I20, is currently under construction and aims to begin operation in late 2009 and early 2010. The beamline aims to cover applications from physics, chemistry and biology through materials, environmental and geological science. Three very distinctive modes of operation will be offered at the beamline: scanning X-ray Absorption spectroscopy (XAS), XAS in dispersive mode, and X-ray emission spectroscopy (XES). To achieve this, the beamline has been designed around two independent experimental end-stations operating from a pair of canted wigglers located in a 5m diamond straight section. One branch of the beamline will deliver monochromatic x-ray radiation of high spectral purity to one of the experimental hutches, whilst the other branch will constitute an energy dispersive spectrometer. The novel design of the beamline allows both branches to operate simultaneously.

  16. Advanced light source vacuum policy and vacuum guidelines for beamlines and experiment endstations

    International Nuclear Information System (INIS)

    Hussain, Z.

    1995-08-01

    The purpose of this document is to: (1) Explain the ALS vacuum policy and specifications for beamlines and experiment endstations. (2) Provide guidelines related to ALS vacuum policy to assist in designing beamlines which are in accordance with ALS vacuum policy. This document supersedes LSBL-116. The Advanced Light Source is a third generation synchrotron radiation source whose beam lifetime depends on the quality of the vacuum in the storage ring and the connecting beamlines. The storage ring and most of the beamlines share a common vacuum and are operated under ultra-high-vacuum (UHV) conditions. All endstations and beamline equipment must be operated so as to avoid contamination of beamline components, and must include proper safeguards to protect the storage ring vacuum from an accidental break in the beamline or endstation vacuum systems. The primary gas load during operation is due to thermal desorption and electron/photon induced desorption of contaminants from the interior of the vacuum vessel and its components. The desorption rates are considerably higher for hydrocarbon contamination, thus considerable emphasis is placed on eliminating these sources of contaminants. All vacuum components in a beamline and endstation must meet the ALS vacuum specifications. The vacuum design of both beamlines and endstations must be approved by the ALS Beamline Review Committee (BRC) before vacuum connections to the storage ring are made. The vacuum design is first checked during the Beamline Design Review (BDR) held before construction of the beamline equipment begins. Any deviation from the ALS vacuum specifications must be approved by the BRC prior to installation of the equipment on the ALS floor. Any modification that is incorporated into a vacuum assembly without the written approval of the BRC is done at the user's risk and may lead to rejection of the whole assembly

  17. Low cost ESR based X-ray beamline for lithography experimentation

    Energy Technology Data Exchange (ETDEWEB)

    Kovacs, S.; Doumas, A.; Truncale, M. (Grumman Corp., Bethpage, NY (United States). Space and Electronics Div.)

    1992-08-01

    Any application of the electron storage ring (ESR) based X-ray lithography technology requires an X-ray radiation transport system to transfer the synchrotron radiation into a spectrum defined by the lithography process requirements. Structure of this transport system (i.e. the beamline) depends on the nature of the application. In this paper a beamline conceptual design will be discussed. The beamline is intended for the developmment of X-ray lithography technology. (orig.).

  18. Thermal damage study of beryllium windows used as vacuum barriers in synchrotron radiation beamlines

    International Nuclear Information System (INIS)

    Holdener, F.R.; Johnson, G.L.; Karpenko, V.P.; Wiggins, R.K.; Cerino, J.A.; Dormiani, M.T.; Youngman, B.P.; Hoyt, E.W.

    1987-01-01

    An experimental study to investigate thermal-induced damage to SSRL-designed beryllium foil windows was performed at LLNL's Laser Welding Research Facility. The primary goal of this study was to determine the threshold at which thermal-stress-induced damage occurs in these commonly used vacuum barriers. An Nd:Yag pulsed laser with cylindrical optics and a carefully designed test cell provided a test environment that closely resembles the actual beamline conditions at SSRL. Tests performed on two beryllium window geometries, with different vertical aperture dimensions but equal foil thicknesses of 0.254 mm, resulted in two focused total-power thresholds at which incipient damage was determined. For a beam spot size similar to that of the Beamline-X Wiggler Line, onset of surface damage for a 5-mm by 25-mm aperture window was observed at 170 W after 174,000 laser pulses (1.2-ms pulse at 100 pps). A second window with double the vertical aperture dimension (10 mm by 25 mm) was observed to have surface cracking after 180,000 laser pulses with 85 W impinging its front surface. It failed after approximately 1,000,000 pulses. Another window of the same type (10 mm by 25 mm) received 2,160,000 laser pulses at 74.4 W, and subsequent metallographic sectioning revealed no signs of through-thickness damage. Comparison of windows with equal foil thicknesses and aperture dimensions has effectively identified the heat flux limit for incipient failure. The data show that halving the aperture's vertical dimension allows doubling the total incident power for equivalent onsets of thermal-induced damage

  19. The EIS beamline at the seeded free-electron laser FERMI

    Science.gov (United States)

    Simoncig, A.; Mincigrucci, R.; Principi, E.; Bencivenga, F.; Calvi, A.; Foglia, L.; Kurdi, G.; Raimondi, L.; Manfredda, M.; Mahne, N.; Gobessi, R.; Gerusina, S.; Fava, C.; Zangrando, M.; Matruglio, A.; Dal Zilio, S.; Masciotti, V.; Masciovecchio, C.

    2017-05-01

    Among the fourth-generation light sources, the Italian free-electron laser (FEL) FERMI is the only one operating in the high-gain harmonic generation (HGHG) seeding mode. FERMI delivers pulses characterized by a quasi transform limited temporal structure, photon energies lying in the extreme ultra-violet (EUV) region, supreme transversal and longitudinal coherences, high peak brilliance, and full control of the polarization. Such state of the art performances recently opened the doors to a new class of time-resolved spectroscopies, difficult or even impossible to be performed using self-amplified spontaneous sources (SASE) light sources. FERMI is currently equipped with three operating beamlines opened to external users (DiProI, LDM and EIS), while two more are under commissioning (MagneDYN and TeraFERMI). Here, we present the recent highlights of the EIS (Elastic and Inelastic Scattering) beamline, which has been purposely designed to take full advantage from the coherence, the intensity, the harmonics content, and the temporal duration of the pulses. EIS is a flexible experimental facility for time-resolved EUV scattering experiments on condensed matter systems, consisting of two independent end-stations. The first one (EIS-TIMEX) aims to study materials in metastable and warm dense matter (WDM) conditions, while the second end-station (EIS-TIMER) is fully oriented to the extension of four-wave mixing (FWM) spectroscopies towards the EUV spectral regions, trying to reveal the behavior of matter in portions of the mesoscopic regime of exchanged momentum impossible to be probed using conventional light sources.

  20. Characterization of the Metrology beamline at the SOLEIL synchrotron and application to the determination of mass attenuation coefficients of Ag and Sn in the range 3.5 ≤ E ≤ 28 keV

    International Nuclear Information System (INIS)

    Menesguen, Y.; Lepy, M.C.

    2011-01-01

    This work presents the new Metrology beamline at the SOLEIL synchrotron facility and a first attempt to quantitative measurements of mass attenuation coefficients for Ag and Sn performed on the hard X-ray branch. We first describe the beamline itself and the characterization performed of the unfocused monochromatic beam running mode. We performed a first experimental measurement of mass attenuation coefficients in the range 3.5 ≤ E ≤ 28 keV and we also derived the K-absorption and L-absorption jump ratios. The results are compared with theoretical values as well as with other experimental data and agree well with previous published values. (authors)