APF530 versus ondansetron, each in a guideline-recommended three-drug regimen, for the prevention of chemotherapy-induced nausea and vomiting due to anthracycline plus cyclophosphamide–based highly emetogenic chemotherapy regimens: a post hoc subgroup analysis of the Phase III randomized MAGIC trial

Directory of Open Access Journals (Sweden)

Schnadig ID

2017-05-01

end point was delayed-phase (>24–120 hours complete response (CR. Results: APF530 versus ondansetron regimens achieved numerically better CINV control in delayed and overall (0–120 hours phases for CR, complete control, total response, rescue medication use, and proportion with no nausea. APF530 trends are consistent with the overall population, although not statistically superior given the underpowered AC subgroup analysis. The APF530 regimen in this population was generally well tolerated, with safety comparable to that of the overall population.Conclusion: APF530 plus fosaprepitant and dexamethasone effectively prevented CINV among patients receiving AC-based HEC, a large subgroup in whom CINV control has traditionally been challenging. Keywords: APF530, extended release granisetron, chemotherapy-induced nausea and vomiting (CINV, highly emetogenic chemotherapy (HEC, anthracycline, cyclophosphamide

A randomized, placebo-controlled, four-period crossover, definitive QT study of the effects of APF530 exposure, high-dose intravenous granisetron, and moxifloxacin on QTc prolongation

Directory of Open Access Journals (Sweden)

Mason JW

2014-03-01

Full Text Available Jay W Mason,1 Thomas E Moon,2 Erin O’Boyle,3 Albert Dietz41Department of Medicine, University of Utah, Salt Lake City, UT, 2Tarizona eHealth Services, Inc., San Carlos, CA, 3AP Pharma, Redwood City, CA, 4Spaulding Clinical Research, West Bend, WI, USABackground: Regulatory concern about potential QT-interval prolongation by serotonin-receptor antagonist antiemetics prompted product-label changes. The first-generation serotonin-receptor antagonist granisetron is available in oral (PO, intravenous (IV, and transdermal formulations. APF530 is a formulation that provides sustained release of granisetron when administered as a single subcutaneous (SC injection. The Phase I study reported here evaluated effects of APF530 on electrocardiographic intervals.Methods: This single-site, double-blind, placebo-controlled, four-period crossover trial randomized healthy men and women to receive varying sequences of APF530 1 g SC, granisetron 50 μg/kg IV, moxifloxacin 400 mg PO, and placebo. Subjects were assessed for 49 hours after each treatment. The primary objective was to evaluate differences between baseline-adjusted, heart rate-corrected QT-interval change using the Fridericia rate correction (dQTcF for APF530 1 g SC and placebo. Electrocardiograms were performed at various times throughout the assessment period. Pharmacokinetics and safety were evaluated.Results: The upper one-sided 95% confidence interval (CI for mean baseline-adjusted dQTcF at each post-dose time point between APF530 and placebo excluded 10 ms, indicating that APF530 1 g SC had no clinically significant effect on QTcF. Maximum observed QTcF change was 4.15 ms (90% CI, 0.94 to 7.36 at Hour 3. No clinically significant changes in other electrocardiogram intervals were observed. APF530 SC pharmacokinetics were as expected, with slow absorption (maximum plasma concentration 35.8 ng/mL, median time to maximum plasma concentration 11.1 hours and slow elimination (mean half-life 18.6 hours

Pharmacokinetics, safety, and efficacy of APF530 (extended-release granisetron) in patients receiving moderately or highly emetogenic chemotherapy: results of two Phase II trials

International Nuclear Information System (INIS)

Gabrail, Nashat; Yanagihara, Ronald; Spaczyński, Marek; Cooper, William; O’Boyle, Erin; Smith, Carrie; Boccia, Ralph

2015-01-01

Despite advances with new therapies, a significant proportion of patients (>30%) suffer delayed-onset chemotherapy-induced nausea and vomiting (CINV) despite use of antiemetics. APF530 is a sustained-release subcutaneous (SC) formulation of granisetron for preventing CINV. APF530 pharmacokinetics, safety, and efficacy were studied in two open-label, single-dose Phase II trials (C2005-01 and C2007-01, respectively) in patients receiving moderately emetogenic chemotherapy or highly emetogenic chemotherapy. In C2005-01, 45 patients received APF530 250, 500, or 750 mg SC (granisetron 5, 10, or 15 mg, respectively). In C2007-01, 35 patients were randomized to APF530 250 or 500 mg SC. Injections were given 30 to 60 minutes before single-day moderately emetogenic chemotherapy or highly emetogenic chemotherapy. Plasma granisetron was measured from predose to 168 hours after study drug administration. Safety and efficacy were also evaluated. APF530 pharmacokinetics were dose proportional, with slow absorption and elimination of granisetron after a single SC dose. Median time to maximum plasma concentration and half-life were similar for APF530 250 and 500 mg in both trials, with no differences between the groups receiving moderately and highly emetogenic chemotherapy. Exposure to granisetron was maintained at a therapeutic level over the delayed-onset phase, at least 168 hours. Adverse events in both trials were as expected for granisetron; injection site reactions (eg, erythema and induration) were predominantly mild and seen in ≤20% of patients. Complete responses (no emesis, with no rescue medication) were obtained in the acute, delayed, and overall phases in ≥80% and ≥75% of patients in both trials with the 250 and 500 mg doses, respectively. After a single injection of APF530, there were dose-proportional pharmacokinetics and sustained concentrations of granisetron over 168 hours. The 250 and 500 mg doses were well tolerated and maintained therapeutic granisetron

Validation of APF as a Urinary Biomarker for Interstitial Cystitis

Science.gov (United States)

2016-12-01

approach taken to increase the sensitivity of the SPR assay has resulted in the production of five purified monoclonal antibodies that display specific...0454 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Sonia Lobo Planey, Ph.D. 5d. PROJECT NUMBER 5e. TASK NUMBER E-Mail:splaney@tcmc.edu 5f. WORK UNIT...specimens from 14 (47%) of 30 women diagnosed with IC/PBS demonstrated as-APF binding activity to the CKAP4127-360 biosensor compared with 22 (73%) of 30

Optimization Based Shunt APF Controller to Mitigate Reactive Power, Burden of Neutral Conductor, Current Harmonics and Improve cosɸ

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P. Anjana

2017-03-01

Full Text Available This paper presents a Modified Gravitational Search Algorithm (MGSA to improve the performance of PI controller in varying load condition. The proposed approach is capable of mitigating reactive power, neutral current, source current THD and significant improvement in power factor nearly unity (0.997. The DC link voltage across the capacitor is controlled by PI controller which is deciding the performance of shunt APF. Hence, the robust optimization technique based integral time square error (ITSE with consideration of weight factor (α & β, maximum overshoot ((|(∆_Ve ̅〖(n〗_max | and setling time t_s-t_0, is providing the optimum solution of Kp & Ki. The robustness of proposed objective function and algorithm compared with GSA based three other error criterion techniques. The efficiency of the proposed controller has been tested over nonlinear and unbalance loading condition. The performance of ITSE based MGSA-PI controller is batter then other three error criterion techniques. The values of THD are below the mark of 5% specified in IEEE-519 standard.

Effects of Field Distortions in IH-APF Linac for a Compact Medical Accelerator

CERN Document Server

Kapin, Valery; Yamada, Satoru

2004-01-01

The project on developing compact medical accelerators for the tumor therapy using carbon ions has been started at the National Institute of Radiological Sciences (NIRS). Alternating-phase-focused (APF) linac using an interdigital H-mode (IH) cavity has been proposed for the injector linac. The IH-cavity is a doubly ridged circular resonator loaded by the drift-tubes mounted on ridges with supporting stems. The effects of intrinsic and random field distortions in a practical design of the 4-Mev/u 200-MHz IH-APF linac are considered. The intrinsic field distortions in the IH-cavity are caused by an asymmetry of the gap fields due to presence of the stems and pair of ridges. The random field distortions are caused by drift-tube misalignments and non-regular deviations of the gap voltages from programmed values. The RF fields in the IH-cavity have been calculated using Microwave Studio (MWS) code. The effects of field distortions on beam dynamics have been simulated numerically. The intrinsic field distortions a...

Randomized phase III trial of APF530 versus palonosetron in the prevention of chemotherapy-induced nausea and vomiting in a subset of patients with breast cancer receiving moderately or highly emetogenic chemotherapy

International Nuclear Information System (INIS)

Boccia, Ralph; O’Boyle, Erin; Cooper, William

2016-01-01

APF530 provides controlled, sustained-release granisetron for preventing acute (0–24 h) and delayed (24–120 h) chemotherapy-induced nausea and vomiting (CINV). In a phase III trial, APF530 was noninferior to palonosetron in preventing acute CINV following single-dose moderately (MEC) or highly emetogenic chemotherapy (HEC) and delayed CINV in MEC (MEC and HEC defined by Hesketh criteria). This exploratory subanalysis was conducted in the breast cancer subpopulation. Patients were randomized to subcutaneous APF530 250 or 500 mg (granisetron 5 or 10 mg) or intravenous palonosetron 0.25 mg during cycle 1. Palonosetron patients were randomized to APF530 for cycles 2 to 4. The primary efficacy end point was complete response (CR, no emesis or rescue medication) in cycle 1. Among breast cancer patients (n = 423 MEC, n = 185 HEC), > 70 % received anthracycline-containing regimens in each emetogenicity subgroup. There were no significant between-group differences in CRs in cycle 1 for acute (APF530 250 mg: MEC 71 %, HEC 77 %; 500 mg: MEC 73 %, HEC 73 %; palonosetron: MEC 68 %, HEC 66 %) and delayed (APF530 250 mg: MEC 46 %, HEC 58 %; 500 mg: MEC 48 %, HEC 63 %; palonosetron: MEC 52 %, HEC 52 %) CINV. There were no significant differences in within-cycle CRs between APF530 doses for acute and delayed CINV in MEC or HEC in cycles 2 to 4; CRs trended higher in later cycles, with no notable differences in adverse events between breast cancer and overall populations. APF530 effectively prevented acute and delayed CINV over 4 chemotherapy cycles in breast cancer patients receiving MEC or HEC. Clinicaltrials.gov identifier: NCT00343460 (June 22, 2006)

Efficacy of 1.23% APF gel applications on incipient carious lesions: a double-blind randomized clinical trial

Directory of Open Access Journals (Sweden)

Maria Laura Menezes Bonow

2013-06-01

Full Text Available The aim of this double-blind randomized clinical trial was to evaluate the efficacy of 1.23% APF gel application on the arrest of active incipient carious lesions in children. Sixty 7- to 12-year-old children, with active incipient lesions were included in the study. Children were divided randomly into 2 groups: 1.23% APF gel and placebo gel applications. Each group received 8 weekly applications of treatment. The lesions were re-evaluated at the 4th and 8th appointments. Poisson regression analysis was used to estimate relative risks of the presence of active white spot lesions. Groups showed similar results (PR = 1.67; CI 95% 0.69–3.98. The persistence of at least 1 active lesion was associated with a higher number of lesions in the baseline (PR = 2.67; CI 95% 1.19–6.03, but not with sugar intake (PR = 1.06; CI 95% 0.56–2.86 and previous exposure to fluoride dentifrice (PR = 1.26; CI 95% 0.49–2.29. The trial demonstrates the equivalence of the treatments. The use of the APF gel showed no additional benefits in this sample of children exposed to fluoridated water and dentifrice. The professional dental plaque removal in both groups may also account for the resulting equivalence of the treatments.

Reearch on Three-phase Four-wire System APF Based on Dual Technology%基于二重化技术的三相四线制APF研究

Institute of Scientific and Technical Information of China (English)

陈楠楠

2013-01-01

Through contrasting and analyzing the advantages and disadvantages of two kinds of topologies of three-phase four-wire system active power filter (APF), the four legs topology structure with better compensation effect is chosen. Designated sub harmonics are checked by adopting the improved ip-iq type detection algorithm and gradation compensates. It can neatly select the number of compensating harmonics to suit the needs of different industrial application. The simulation results show that designed three-phase four wire system with dual APF has very good harmonic effect and can effectively inhibit neutral current.%通过对比分析三相四线制有源电力滤波器(APF)的两种拓扑结构的优缺点，选择了补偿效果更好的四桥臂拓扑结构。采用改进的ip-iq型检测算法对特指的次谐波进行检测，分次进行补偿，可以灵活选择补偿谐波的次数，以适应不同的工业现场的需要。仿真结果表明，设计的三相四线制二重化APF具有很好的谐波效果并能有效地抑制中线电流。

Popular heavy particle beam cancer therapeutic system (3). Development of high efficiency compact incident system-2. Great success of beam test of new APF-IH type DTL

International Nuclear Information System (INIS)

Yamamoto, Kazuo; Iwata, Yoshiyuki

2006-01-01

High efficiency compact incident system consists of an electron cyclotron resonance (ECR) ion source, a radio frequency quadrupole (RFQ) linear accelerator and an interdigital H-mode (IH) drift tube linear accelerator (DTL). IH type DTL and alternating phase focusing (APF) method is explained. Its special features, production, and beam test are reported. The electric field generation method, outline of the APF method, drift tube, IH type DTL, distribution of electric field and voltage, set up of beam test, ECR ion source and incident line, the inside structure of the RFQ type linear accelerator and the APF-IH type DTL, matching Q lens section, beam, emittance, measurement results of momentum dispersion are illustrated. (S.Y.)

Pharmacokinetics, safety, and efficacy of APF530 (extended-release granisetron in patients receiving moderately or highly emetogenic chemotherapy: results of two Phase II trials

Directory of Open Access Journals (Sweden)

Gabrail N

2015-03-01

Full Text Available Nashat Gabrail,1 Ronald Yanagihara,2 Marek Spaczyński,3 William Cooper,4 Erin O'Boyle,5 Carrie Smith,1 Ralph Boccia6 1Gabrail Cancer Center, Canton, OH, USA; 2St Louise Regional Hospital, Gilroy, CA, USA; 3Department of Gynecology, Obstetrics and Gynecologic Oncology, University of Medical Sciences, Poznan, Poland; 4TFS International, Flemington, NJ, USA; 5FibroGen, Inc., San Francisco, CA, USA; 6Center for Cancer and Blood Disorders, Bethesda, MD, USA Background: Despite advances with new therapies, a significant proportion of patients (>30% suffer delayed-onset chemotherapy-induced nausea and vomiting (CINV despite use of antiemetics. APF530 is a sustained-release subcutaneous (SC formulation of granisetron for preventing CINV. APF530 pharmacokinetics, safety, and efficacy were studied in two open-label, single-dose Phase II trials (C2005-01 and C2007-01, respectively in patients receiving moderately emetogenic chemotherapy or highly emetogenic chemotherapy. Methods: In C2005-01, 45 patients received APF530 250, 500, or 750 mg SC (granisetron 5, 10, or 15 mg, respectively. In C2007-01, 35 patients were randomized to APF530 250 or 500 mg SC. Injections were given 30 to 60 minutes before single-day moderately emetogenic chemotherapy or highly emetogenic chemotherapy. Plasma granisetron was measured from predose to 168 hours after study drug administration. Safety and efficacy were also evaluated. Results: APF530 pharmacokinetics were dose proportional, with slow absorption and elimination of granisetron after a single SC dose. Median time to maximum plasma concentration and half-life were similar for APF530 250 and 500 mg in both trials, with no differences between the groups receiving moderately and highly emetogenic chemotherapy. Exposure to granisetron was maintained at a therapeutic level over the delayed-onset phase, at least 168 hours. Adverse events in both trials were as expected for granisetron; injection site reactions (eg, erythema

Comparison of an extended-release formulation of granisetron (APF530) versus palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with moderately or highly emetogenic chemotherapy: results of a prospective, randomized, double-blind, noninferiority phase 3 trial.

Science.gov (United States)

Raftopoulos, Harry; Cooper, William; O'Boyle, Erin; Gabrail, Nashat; Boccia, Ralph; Gralla, Richard J

2015-03-01

Subcutaneous APF530 provides controlled sustained release of granisetron to prevent acute (0-24 h) and delayed (24-120 h) chemotherapy-induced nausea and vomiting (CINV). This randomized, double-blind phase 3 trial compared APF530 and palonosetron in preventing acute and delayed CINV after moderately (MEC) or highly emetogenic chemotherapy (HEC). Patients receiving single-day MEC or HEC received single-dose APF530 250 or 500 mg subcutaneously (SC) (granisetron 5 or 10 mg) or intravenous palonosetron 0.25 mg. Primary objectives were to establish APF530 noninferiority to palonosetron for preventing acute CINV following MEC or HEC and delayed CINV following MEC and to determine APF530 superiority to palonosetron for preventing delayed CINV following HEC. The primary efficacy end point was complete response (CR [using CI difference for APF530-palonosetron]). A lower confidence bound greater than -15 % indicated noninferiority. In the modified intent-to-treat population (MEC = 634; HEC = 707), both APF530 doses were noninferior to palonosetron in preventing acute CINV after MEC (CRs 74.8 % [-9.8, 9.3] and 76.9 % [-7.5, 11.4], respectively, vs. 75.0 % palonosetron) and after HEC (CRs 77.7 % [-11.5, 5.5] and 81.3 % [-7.7, 8.7], respectively, vs. 80.7 % palonosetron). APF530 500 mg was noninferior to palonosetron in preventing delayed CINV after MEC (CR 58.5 % [-9.5, 12.1] vs. 57.2 % palonosetron) but not superior in preventing delayed CINV after HEC. Adverse events were generally mild and unrelated to treatment, the most common (excluding injection-site reactions) being constipation. A single subcutaneous APF530 injection offers a convenient alternative to palonosetron for preventing acute and delayed CINV after MEC or HEC.

Evaluation of primary tooth enamel surface morphology and microhardness after Nd:YAG laser irradiation and APF gel treatment--an in vitro study.

Science.gov (United States)

Banda, Naveen Reddy; Vanaja Reddy, G; Shashikiran, N D

2011-01-01

Laser irradiation and fluoride has been used as a preventive tool to combat dental caries in permanent teeth, but little has been done for primary teeth which are more prone to caries. The purpose of this study was to evaluate microhardness alterations in the primary tooth enamel after Nd-YAG laser irradiation alone and combined with topical fluoride treatment either before or after Nd-YAG laser irradiation. Ten primary molars were sectioned and assigned randomly to: control group, Nd-YAG laser irradiation, Nd-YAG lasing before APF and APF followed by Nd-YAG lasing. The groups were evaluated for microhardness. Surface morphological changes were observed using SEM. Statistical comparisons were performed. The control group's SEM showed a relatively smooth enamel surface and lasing group had fine cracks and porosities. In the lasing + fluoride group a homogenous confluent surface was seen. In the fluoride + lasing group an irregular contour with marked crack propagation was noted. There was a significant increase in the microhardness of the treatment groups. Nd-YAG laser irradiation and combined APF treatment of the primary tooth enamel gave morphologically hardened enamel surface which can be a protective barrier against a cariogenic attack.

Using FLUKA to Study Concrete Square Shield Performance in Attenuation of Neutron Radiation Produced by APF Plasma Focus Neutron Source

Science.gov (United States)

Nemati, M. J.; Habibi, M.; Amrollahi, R.

2013-04-01

In 2010, representatives from the Nuclear Engineering and physics Department of Amirkabir University of Technology (AUT) requested development of a project with the objective of determining the performance of a concrete shield for their Plasma Focus as neutron source. The project team in Laboratory of Nuclear Engineering and physics department of Amirkabir University of Technology choose some shape of shield to study on their performance with Monte Carlo code. In the present work, the capability of Monte Carlo code FLUKA will be explored to model the APF Plasma Focus, and investigating the neutron fluence on the square concrete shield in each region of problem. The physical models embedded in FLUKA are mentioned, as well as examples of benchmarking against future experimental data. As a result of this study suitable thickness of concrete for shielding APF will be considered.

Control of a three-phase four-wire shunt-active power filter based on DC-bus energy regulation

DEFF Research Database (Denmark)

Blaabjerg, Frede; Teodorescu, Remus; Rodriguez, Pedro

2008-01-01

This paper presents a nonconventional three-phase four-wire shunt active power filter (APF) topology controlled by using an energy approach. A general study of power terms involved in the operation of the four-wire APF is conducted in order to evidence the relationship between instantaneous energy...... stored in the DC bus and active power requirements on the APF. Harmonics and imbalances both on the utility voltage and load current have been considered and the power developed by the active power filter has been evaluated. This study allows designing a controller for the APF based on the regulation...

Final Deactivation Project report on the Alpha Powder Facility, Building 3028, at Oak Ridge National Laboratory, Oak Ridge, Tennessee

International Nuclear Information System (INIS)

1997-04-01

This report documents the condition of the Alpha Powder Facility (APF), Building 3028, after completion of deactivation activities. Activities conducted to place the facility in a safe and environmentally sound condition for transfer to the U.S. Department of Energy (DOE) Office of Environmental Restoration (EM-40) program are outlined. A history and profile of the facility prior to commencing deactivation activities and a profile of the building after completion of deactivation activities are provided. Turnover items, such as the post-deactivation surveillance and maintenance (S ampersand M) plan, remaining hazardous materials, radiological controls, safeguards and security, quality assurance, facility operations, and supporting documentation provided for in the DOE Nuclear Materials and Facility Stabilization Program (EM-60) turnover package are discussed

Final Deactivation Project report on the Alpha Powder Facility, Building 3028, at Oak Ridge National Laboratory, Oak Ridge, Tennessee

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-04-01

This report documents the condition of the Alpha Powder Facility (APF), Building 3028, after completion of deactivation activities. Activities conducted to place the facility in a safe and environmentally sound condition for transfer to the U.S. Department of Energy (DOE) Office of Environmental Restoration (EM-40) program are outlined. A history and profile of the facility prior to commencing deactivation activities and a profile of the building after completion of deactivation activities are provided. Turnover items, such as the post-deactivation surveillance and maintenance (S&M) plan, remaining hazardous materials, radiological controls, safeguards and security, quality assurance, facility operations, and supporting documentation provided for in the DOE Nuclear Materials and Facility Stabilization Program (EM-60) turnover package are discussed.

A Motion Planning Method for Omnidirectional Mobile Robot Based on the Anisotropic Characteristics

Directory of Open Access Journals (Sweden)

Chuntao Leng

2008-11-01

Full Text Available A more suitable motion planning method for an omni-directional mobile robot (OMR, an improved APF method (iAPF, is proposed in this paper by introducing the revolving factor into the artificial potential field (APF. Accordingly, the motion direction derived from traditional artificial potential field (tAPF is regulated. The maximum velocity, maximum acceleration and energy consumption of the OMR moving in different directions are analyzed, based on the kinematic and dynamic constraints of an OMR, and the anisotropy of OMR is presented in this paper. Then the novel concept of an Anisotropic-Function is proposed to indicate the quality of motion in different directions, which can make a very favorable trade-off between time-optimality, stability and efficacy-optimality. In order to obtain the optimal motion, the path that the robot can take in order to avoid the obstacle safely and reach the goal in a shorter path is deduced. Finally, simulations and experiments are carried out to demonstrate that the motion resulting from the iAPF is high-speed, highly stable and highly efficient when compared to the tAPF.

A Comparison of Fluoride Uptake by Sound Enamel Following Application of Sodium Fluoride Mouthrinses and APF Gels Produced in Iran with Standardized Foreign Samples

Directory of Open Access Journals (Sweden)

A Kowsari

2002-02-01

Full Text Available The goal of this investigation is to compare the extent of fluoride uptake by sound enamel following application of two commercial mouthrinses containing sodium fluoride (0.2% and a topical gel containing APF (1.23% produced in Iran with those of foreign standardized ones. Sixty extracted premolars were used. Each tooth was divided into two lingual and buccal halves, one half as control, the other one as experimental. Enamel biopsy technique (two- step acid etching was used to determine the concentration of fluoride and calcium in each sample. For data comparison and fluoride uptake estimation, the depths of layers with the use of linear regression analysis were standardized to 25 and 50um. The analysis showed that in Iranian mouthrinse no. 1, there is linear correlation between fluoride concentration and enamel depth, in both control and experimental group at the first and second layers, while, in other groups, this correlation was observed just at the first layer (superficial enamel layer. The greatest fluoride uptake was seen at Iranian mouthrinse no.2 and the least was seen at foreign mouthrinse no. 3. From among two APF gels, the greatest uptake was observed at gel no. 1 (Iranian. The results showed that all three Iranian products increase fluoride content of enamel, moreover the level of fluoride uptake, while applying Iranian products, in comparison with foreign ones, shows considerable increase.

Experimental Study of Current Discharge Behavior and Hard X-ray Anisotropy by APF Plasma Focus Device

Science.gov (United States)

Habibi, M.; Amrollahi, R.; Attaran, M.

2009-03-01

Amirkabir (APF) is a new Mather-type plasma focus device (16 kV, 36 μf, and 115 nH). In this work we present some experimental results as variation of discharge current signal respect to applied voltage at the optimum pressure, focusing time of plasma versus gas pressure, and variations of current discharge with different insulator sleeve dimensions. As we prospected optimum pressure tending to increase as we tried to higher voltage levels. The time taken by the current sheath to lift-off the insulator surface and therefore quality of pinched plasma depends on the length of the insulator sleeve. The results show that the insulator diameter can influence on pinch quality. Behavior of hard X-ray (HXR) signals with the pressure and also anisotropy of HXR investigated by the use of two scintillation detectors. The distribution of HXR intensity shows a large anisotropy with a maximum intensity between 22.5° and 45° and also between -22.5° and -67.5°.

Experimental Fuels Facility Re-categorization Based on Facility Segmentation

Energy Technology Data Exchange (ETDEWEB)

Reiss, Troy P.; Andrus, Jason

2016-07-01

The Experimental Fuels Facility (EFF) (MFC-794) at the Materials and Fuels Complex (MFC) located on the Idaho National Laboratory (INL) Site was originally constructed to provide controlled-access, indoor storage for radiological contaminated equipment. Use of the facility was expanded to provide a controlled environment for repairing contaminated equipment and characterizing, repackaging, and treating waste. The EFF facility is also used for research and development services, including fuel fabrication. EFF was originally categorized as a LTHC-3 radiological facility based on facility operations and facility radiological inventories. Newly planned program activities identified the need to receive quantities of fissionable materials in excess of the single parameter subcritical limit in ANSI/ANS-8.1, “Nuclear Criticality Safety in Operations with Fissionable Materials Outside Reactors” (identified as “criticality list” quantities in DOE-STD-1027-92, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports,” Attachment 1, Table A.1). Since the proposed inventory of fissionable materials inside EFF may be greater than the single parameter sub-critical limit of 700 g of U-235 equivalent, the initial re-categorization is Hazard Category (HC) 2 based upon a potential criticality hazard. This paper details the facility hazard categorization performed for the EFF. The categorization was necessary to determine (a) the need for further safety analysis in accordance with LWP-10802, “INL Facility Categorization,” and (b) compliance with 10 Code of Federal Regulations (CFR) 830, Subpart B, “Safety Basis Requirements.” Based on the segmentation argument presented in this paper, the final hazard categorization for the facility is LTHC-3. Department of Energy Idaho (DOE-ID) approval of the final hazard categorization determined by this hazard assessment document (HAD) was required per the

An Active Power Filter Based on a Three-Level Inverter and 3D-SVPWM for Selective Harmonic and Reactive Compensation

Directory of Open Access Journals (Sweden)

José Luis Monroy-Morales

2017-03-01

Full Text Available Active Power Filters (APFs have been used for reducing waveform distortion and improving power quality. However, this function can be improved by means of a selective harmonic compensation. Since an APF has rating restrictions, it is convenient to have the option of selecting an individual or a set of particular harmonics in order to compensate and apply the total APF capabilities to eliminate these harmonics, in particular those with a greater impact on the Total Harmonic Distortion (THD. This paper presents the development of a new APF prototype based on a three-phase three-level Neutral Point Clamped (NPC inverter with selective harmonic compensation capabilities and reactive power compensation. The selective harmonic compensation approach uses several Synchronous Rotating Frames (SRF, to detect and control individual or a set of harmonics using d and q variables. The APF includes a Three-Dimensional Space Vector Modulator (3D-SVPWM in order to generate the compensation currents. Because of its multilevel topology, the proposed active power filter can be used in diverse power quality applications at sub-transmission and distribution voltage levels. Simulation and experimental results are shown to validate the proposed solution and assess the prototype performance in different scenarios.

Control Strategy of Active Power Filter Based on Modular Multilevel Converter

Science.gov (United States)

Xie, Xifeng

2018-03-01

To improve the capacity, pressure resistance and the equivalent switching frequency of active power filter (APF), a control strategy of APF based on Modular Multilevel Converter (MMC) is presented. In this Control Strategy, the indirect current control method is used to achieve active current and reactive current decoupling control; Voltage Balance Control Strategy is to stabilize sub-module capacitor voltage, the predictive current control method is used to Track and control of harmonic currents. As a result, the harmonic current is restrained, and power quality is improved. Finally, the simulation model of active power filter controller based on MMC is established in Matlab/Simulink, the simulation proves that the proposed strategy is feasible and correct.

Stationarity of annual flood peaks during 1951-2010 in the Pearl River basin, China

Science.gov (United States)

Zhang, Qiang; Gu, Xihui; Singh, Vijay P.; Xiao, Mingzhong; Xu, Chong-Yu

2014-11-01

The assumption of stationarity of annual peak flood (APF) records at 28 hydrological stations across the Pearl River basin, China, is tested. Abrupt changes in mean and variance are tested using the Pettitt technique and the Loess method. Trends of APFs are analyzed using the Mann-Kendall method and the Spearman technique. And then the stationarity of the APF series is further investigated by GAMLSS models and long-term persistence. Results indicate that: (1) abrupt changes in mean and variance have similar influences on the changing properties of APFs, such as stationarity. Abrupt changes in mean and variance are only field significant in the East River basin; (2) the change points have a considerable impact on the detection of trends, and these may be attributed to the fact that a abrupt increase or decrease in mean values will affect the trend variations. Besides, for the APF series being free of change points and trend, the GAMLSS models also corroborate stationarity of the APF series; (3) the nonstationarity in the Pearl River basin is mainly due to the existence of the change point. However, the APF series with change points in mean and/or variance are also characterized by long-term persistence, and thus it is infeasible to assert that the abrupt behaviors and/or trends of the APF series are the result of human activities or long-term persistence, especially in the East River basin. Results of this study will provide information for management of water resources and design of hydraulic facilities in the Pearl River basin in a changing environment.

Direct harmonic voltage control strategy for shunt active power filter

DEFF Research Database (Denmark)

Munir, Hafiz Mudassir; Zou, JianXiao; Xie, Chuan

2017-01-01

generation system (DPGS) where the nonlinear loads are highly dispersed. Local harmonic voltage detection based Resistive-APF (R-APF) seems more suitable to be applied in the DPGS, however, R-APF suffers from poor compensation performance and difficulty of parameter tuning. In this paper, a direct harmonic...... voltage control strategy for the S-APF is proposed with local point of common coupling (PCC) voltage detection only. The control strategy design procedure is given in detail. Simulation is conducted in Matlab/Simulink to compare the performance between the R-APF and the proposed method. The results...

Imagery Data Base Facility

Data.gov (United States)

Federal Laboratory Consortium — The Imagery Data Base Facility supports AFRL and other government organizations by providing imagery interpretation and analysis to users for data selection, imagery...

Simulation and Hardware Implementation of Shunt Active Power Filter Based on Synchronous Reference Frame Theory

Directory of Open Access Journals (Sweden)

Karthikrjan Senthilnathan

2018-02-01

Full Text Available This paper describes about the Hybrid Shunt Active Power Filter (HSAPF for the elimination of the current harmonics in the line side of the three phase three wire systems. The Active Power Filter is based on the Voltage Source Converter (VSC topology. The control strategy for the converter is based on Synchronous Reference Frame (SRF theory. The compensation of harmonics is done by the APF which is connected in the shunt configuration to the system. The Shunt APF has the better compensation of current harmonics. The design and implementation of Shunt active power filter is done by MATLAB/Simulink. The real time implementation by using the ATMEGA 8 Microcontroller. The Simulation and Hardware results shows that the current harmonics are eliminated in the system

75 FR 55574 - Joint Public Roundtable on Swap Execution Facilities and Security-Based Swap Execution Facilities

Science.gov (United States)

2010-09-13

...; File No. 4-612] Joint Public Roundtable on Swap Execution Facilities and Security-Based Swap Execution Facilities AGENCY: Commodity Futures Trading Commission (``CFTC'') and Securities and Exchange Commission... discuss swap execution facilities and security-based swap execution facilities in the context of certain...

Robins Air Force Base Solar Cogeneration Facility design

Energy Technology Data Exchange (ETDEWEB)

Pierce, B.L.; Bodenschatz, C.A.

1982-06-01

A conceptual design and a cost estimate have been developed for a Solar Cogeneration Facility at Robins Air Force Base. This demonstration solar facility was designed to generate and deliver electrical power and process steam to the existing base distribution systems. The facility was to have the potential for construction and operation by 1986 and make use of existing technology. Specific objectives during the DOE funded conceptual design program were to: prepare a Solar Cogeneration Facility (overall System) Specification, select a preferred configuration and develop a conceptual design, establish the performance and economic characteristics of the facility, and prepare a development plan for the demonstration program. The Westinghouse team, comprised of the Westinghouse Advanced Energy Systems Division, Heery and Heery, Inc., and Foster Wheeler Solar Development Corporation, in conjunction with the U.S. Air Force Logistics Command and Georgia Power Company, has selected a conceptual design for the facility that will utilize the latest DOE central receiver technology, effectively utilize the energy collected in the application, operate base-loaded every sunny day of the year, and be applicable to a large number of military and industrial facilities throughout the country. The design of the facility incorporates the use of a Collector System, a Receiver System, an Electrical Power Generating System, a Balance of Facility - Steam and Feedwater System, and a Master Control System.

Iterative random vs. Kennard-Stone sampling for IR spectrum-based classification task using PLS2-DA

Science.gov (United States)

Lee, Loong Chuen; Liong, Choong-Yeun; Jemain, Abdul Aziz

2018-04-01

External testing (ET) is preferred over auto-prediction (AP) or k-fold-cross-validation in estimating more realistic predictive ability of a statistical model. With IR spectra, Kennard-stone (KS) sampling algorithm is often used to split the data into training and test sets, i.e. respectively for model construction and for model testing. On the other hand, iterative random sampling (IRS) has not been the favored choice though it is theoretically more likely to produce reliable estimation. The aim of this preliminary work is to compare performances of KS and IRS in sampling a representative training set from an attenuated total reflectance - Fourier transform infrared spectral dataset (of four varieties of blue gel pen inks) for PLS2-DA modeling. The `best' performance achievable from the dataset is estimated with AP on the full dataset (APF, error). Both IRS (n = 200) and KS were used to split the dataset in the ratio of 7:3. The classic decision rule (i.e. maximum value-based) is employed for new sample prediction via partial least squares - discriminant analysis (PLS2-DA). Error rate of each model was estimated repeatedly via: (a) AP on full data (APF, error); (b) AP on training set (APS, error); and (c) ET on the respective test set (ETS, error). A good PLS2-DA model is expected to produce APS, error and EVS, error that is similar to the APF, error. Bearing that in mind, the similarities between (a) APS, error vs. APF, error; (b) ETS, error vs. APF, error and; (c) APS, error vs. ETS, error were evaluated using correlation tests (i.e. Pearson and Spearman's rank test), using series of PLS2-DA models computed from KS-set and IRS-set, respectively. Overall, models constructed from IRS-set exhibits more similarities between the internal and external error rates than the respective KS-set, i.e. less risk of overfitting. In conclusion, IRS is more reliable than KS in sampling representative training set.

Facility-based delivery and maternal and early neonatal mortality in ...

African Journals Online (AJOL)

AJRH Managing Editor

One of the most important ways to address some of the key factors ... services, facility-based delivery, facility delivery, institutional delivery ..... Percent of women reporting delivering in a health facility. Quintile* ranking of facility- based delivery. Maternal. Mortality. Ration. (MMR) per. 1000 Live. Births. African. MMR quintile*.

University-based user facilities: lessons from Tantalus and Aladdin

International Nuclear Information System (INIS)

Huber, D.L.

1985-01-01

The establishment of university-based user facilities is a relatively new development in the federal funding of research in condensed matter science. Because the Synchrotron Radiation Center (SRC) has been a pioneer user facility, a certain degree of experience, both good and bad, has been acquired in the construction and operation of university-based facilities for synchrotron-related research. The history of SRC is discussed and some of the general lessons learned in the area of advanced planning are outlined. No attempt is made to be either definitive or exhaustive. In the present context, a university-based user facility is understood to be a dedicated facility under direct university control where a majority of the users come from outside the local university community

Base isolation for nuclear power and nuclear material facilities

International Nuclear Information System (INIS)

Eidinger, J.M.; Kircher, C.A.; Vaidya, N.; Constantinou, M.; Kelly, J.M.; Seidensticker, R.; Tajirian, F.F.; Ovadia, D.

1989-01-01

This report serves to document the status of the practice for the use of base isolation systems in the design and construction of nuclear power and nuclear material facilities. The report first describes past and current (1989) applications of base isolation in nuclear facilities. The report then provides a brief discussion of non-nuclear applications. Finally, the report summarizes the status of known base-isolation codes and standards

Construction of BIM-based SMART-ITL Facility Management System

International Nuclear Information System (INIS)

Jeon, Woo-Jin; Yi, Sung-Jae; Park, Hyun-Sik; Ryu, Sung-Uk; Bae, Hwang; Hwang, Sang-Chul; Min, Byung-Eui

2015-01-01

The flow area and volume are scaled down to 1/49. The ratio of the hydraulic diameter is 1/7. Therefore, SMART-ITL is a large-scale thermalhydraulic test facility with about 45 m height, which is consisted of 10 m underground and 35 m from the ground level. Until now, the management of design data and maintenance of large scale test facilities have been managed based on hard-copy information. Recently, Thermal Hydraulics Safety Research Division (THSRD) at Korea Atomic Energy Research Institute (KAERI) has developed Facility Management System (FMS) based Building Information Modeling (BIM) to manage its design data more effectively for these large scale test facilities of SMART-ITL and ATLAS, and this BIM technology has been applied to SMART-ITL at the first. This study proposed a method of effective management and maintenance of design data applied to the SMART-ITL. That is, a FMS was developed based on the BIM technology for SMART-ITL. Figure 2 shows an overview of FMS development process based on BIM technology. SMART-ITL FMS facilitates its management and maintenance more effectively and accurately by 3- dimensional visualization. It enables the shape information of large scale test facilities to be visualized intuitively in a virtual space, and the efficient maintenance of data and instruments is possible by linking 3D shape information

Construction of BIM-based SMART-ITL Facility Management System

Energy Technology Data Exchange (ETDEWEB)

Jeon, Woo-Jin; Yi, Sung-Jae; Park, Hyun-Sik; Ryu, Sung-Uk; Bae, Hwang [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Hwang, Sang-Chul; Min, Byung-Eui [DDRsoft Co., Daejeon (Korea, Republic of)

2015-10-15

The flow area and volume are scaled down to 1/49. The ratio of the hydraulic diameter is 1/7. Therefore, SMART-ITL is a large-scale thermalhydraulic test facility with about 45 m height, which is consisted of 10 m underground and 35 m from the ground level. Until now, the management of design data and maintenance of large scale test facilities have been managed based on hard-copy information. Recently, Thermal Hydraulics Safety Research Division (THSRD) at Korea Atomic Energy Research Institute (KAERI) has developed Facility Management System (FMS) based Building Information Modeling (BIM) to manage its design data more effectively for these large scale test facilities of SMART-ITL and ATLAS, and this BIM technology has been applied to SMART-ITL at the first. This study proposed a method of effective management and maintenance of design data applied to the SMART-ITL. That is, a FMS was developed based on the BIM technology for SMART-ITL. Figure 2 shows an overview of FMS development process based on BIM technology. SMART-ITL FMS facilitates its management and maintenance more effectively and accurately by 3- dimensional visualization. It enables the shape information of large scale test facilities to be visualized intuitively in a virtual space, and the efficient maintenance of data and instruments is possible by linking 3D shape information.

Hierarchical Control for Voltage Harmonics Compensation in Multi-Area Microgrids

DEFF Research Database (Denmark)

Hashempour, Mohammad M.; Firoozabadi, Mehdi Savaghebi; Quintero, Juan Carlos Vasquez

2015-01-01

In this paper, the power quality of multi-area microgrids is addressed. For this, Active Power Filters (APFs) and Distributed Generators (DGs) inverters are used. To achieve the reference value of power quality indices of different areas, a strategy based on cooperation between DGs and APFs is pr...

XML Based Scientific Data Management Facility

Science.gov (United States)

Mehrotra, P.; Zubair, M.; Bushnell, Dennis M. (Technical Monitor)

2002-01-01

The World Wide Web consortium has developed an Extensible Markup Language (XML) to support the building of better information management infrastructures. The scientific computing community realizing the benefits of XML has designed markup languages for scientific data. In this paper, we propose a XML based scientific data management ,facility, XDMF. The project is motivated by the fact that even though a lot of scientific data is being generated, it is not being shared because of lack of standards and infrastructure support for discovering and transforming the data. The proposed data management facility can be used to discover the scientific data itself, the transformation functions, and also for applying the required transformations. We have built a prototype system of the proposed data management facility that can work on different platforms. We have implemented the system using Java, and Apache XSLT engine Xalan. To support remote data and transformation functions, we had to extend the XSLT specification and the Xalan package.

Operation Cobra: Organizational Pooling and Operational Art in the European Theater

Science.gov (United States)

2017-05-25

an organizational structure based on the idea of “task organizing” and “force pooling.” Task organizing involves the development of situation...essential equipment and personnel based on the day-to-day needs of that unit. A unit that carried enough bridging equipment or truck transport to...in two forms: MSC’s Afloat Pre-positioning Force (APF) and land- based pre-positioned equipment . In the APF, all ships are self-sustaining and have

Second Order Generalized Integrator Based Reference Current Generation Method for Single-Phase Shunt Active Power Filters Under Adverse Grid Conditions

DEFF Research Database (Denmark)

Golestan, Saeed; Monfared, Mohammad; Guerrero, Josep M.

2013-01-01

The reference current generation (RCG) is a crucial part in the control of a shunt active power filter (APF). A variety of RCG techniques have been proposed in literature. Among these, the instantaneous reactive power theory, called pq theory, is probably the most widely used technique. The pq...... theory offers advantages such as satisfactory steady-state and dynamic performance, and at the same time simple digital implementation, however its application was limited to three-phase systems. To exploit the advantages of pq theory in single-phase systems, the single-phase pq theory has been proposed...... recently. In this paper, a simple and effective implementation of the single phase pq theory for single-phase shunt APFs is proposed. The suggested approach is based on employing second order generalized integrators (SOGI), and a phase locked loop (PLL). To fine tune the control parameters, a systematic...

Web-Based Requesting and Scheduling Use of Facilities

Science.gov (United States)

Yeager, Carolyn M.

2010-01-01

Automated User's Training Operations Facility Utilization Request (AutoFUR) is prototype software that administers a Web-based system for requesting and allocating facilities and equipment for astronaut-training classes in conjunction with scheduling the classes. AutoFUR also has potential for similar use in such applications as scheduling flight-simulation equipment and instructors in commercial airplane-pilot training, managing preventive- maintenance facilities, and scheduling operating rooms, doctors, nurses, and medical equipment for surgery. Whereas requesting and allocation of facilities was previously a manual process that entailed examination of documents (including paper drawings) from different sources, AutoFUR partly automates the process and makes all of the relevant information available via the requester s computer. By use of AutoFUR, an instructor can fill out a facility-utilization request (FUR) form on line, consult the applicable flight manifest(s) to determine what equipment is needed and where it should be placed in the training facility, reserve the corresponding hardware listed in a training-hardware inventory database, search for alternative hardware if necessary, submit the FUR for processing, and cause paper forms to be printed. Auto-FUR also maintains a searchable archive of prior FURs.

Ergonomics and simulation-based approach in improving facility layout

Science.gov (United States)

Abad, Jocelyn D.

2018-02-01

The use of the simulation-based technique in facility layout has been a choice in the industry due to its convenience and efficient generation of results. Nevertheless, the solutions generated are not capable of addressing delays due to worker's health and safety which significantly impact overall operational efficiency. It is, therefore, critical to incorporate ergonomics in facility design. In this study, workstation analysis was incorporated into Promodel simulation to improve the facility layout of a garment manufacturing. To test the effectiveness of the method, existing and improved facility designs were measured using comprehensive risk level, efficiency, and productivity. Results indicated that the improved facility layout generated a decrease in comprehensive risk level and rapid upper limb assessment score; an increase of 78% in efficiency and 194% increase in productivity compared to existing design and thus proved that the approach is effective in attaining overall facility design improvement.

Comparison of fluorescence-based techniques for the quantification of particle-induced hydroxyl radicals

Directory of Open Access Journals (Sweden)

Cohn Corey A

2008-02-01

Full Text Available Abstract Background Reactive oxygen species including hydroxyl radicals can cause oxidative stress and mutations. Inhaled particulate matter can trigger formation of hydroxyl radicals, which have been implicated as one of the causes of particulate-induced lung disease. The extreme reactivity of hydroxyl radicals presents challenges to their detection and quantification. Here, three fluorescein derivatives [aminophenyl fluorescamine (APF, amplex ultrared, and dichlorofluorescein (DCFH] and two radical species, proxyl fluorescamine and tempo-9-ac have been compared for their usefulness to measure hydroxyl radicals generated in two different systems: a solution containing ferrous iron and a suspension of pyrite particles. Results APF, amplex ultrared, and DCFH react similarly to the presence of hydroxyl radicals. Proxyl fluorescamine and tempo-9-ac do not react with hydroxyl radicals directly, which reduces their sensitivity. Since both DCFH and amplex ultrared will react with reactive oxygen species other than hydroxyl radicals and another highly reactive species, peroxynitite, they lack specificity. Conclusion The most useful probe evaluated here for hydroxyl radicals formed from cell-free particle suspensions is APF due to its sensitivity and selectivity.

Outcome evaluation of a community center-based program for mothers at high psychosocial risk.

Science.gov (United States)

Rodrigo, María José; Máiquez, María Luisa; Correa, Ana Delia; Martín, Juan Carlos; Rodríguez, Guacimara

2006-09-01

This study reported the outcome evaluation of the "Apoyo Personal y Familiar" (APF) program for poorly-educated mothers from multi-problem families, showing inadequate behavior with their children. APF is a community-based multi-site program delivered through weekly group meetings in municipal resource centers. A total of 340 mothers referred by the municipal social services of Tenerife, Spain were assessed; 185 mothers participated in the APF program that lasted 8 months, and 155 mothers were in the control group. Pre-post test comparisons for the intervention group and post-test comparisons with the control group on self-rating measures of maternal beliefs, personal agency and child-rearing practices were performed. Multivariate tests, t tests and effect sizes (ES) were calculated to determine the program effectiveness on the outcome measures. Mothers' support of nurturist and nativist beliefs and the reported use of Neglect-permissive and Coercive practices significantly decreased after program completion whereas the reported use of Inductive practices significantly increased. Increases in self-efficacy, internal control and role difficulty were also significant in relation to those of the control group. The program was especially effective for older mothers, with fewer children, living in a two-parent family, in urban areas and with either low or medium educational levels. The program was very effective in changing the mothers' perceived competences and modestly effective in changing their beliefs about child development and education and reported child-rearing practices. Changes in personal agency are very important for at-risk parents who feel helpless and with no control over their lives.

Operation and Control of a Direct-Driven PMSG-Based Wind Turbine System with an Auxiliary Parallel Grid-Side Converter

Directory of Open Access Journals (Sweden)

Jiawei Chu

2013-07-01

Full Text Available In this paper, based on the similarity, in structure and principle, between a grid-connected converter for a direct-driven permanent magnet synchronous generator (D-PMSG and an active power filter (APF, a new D-PMSG-based wind turbine (WT system configuration that includes not only an auxiliary converter in parallel with the grid-side converter, but also a coordinated control strategy, is proposed to enhance the low voltage ride through (LVRT capability and improve power quality. During normal operation, the main grid-side converter maintains the DC-link voltage constant, whereas the auxiliary grid-side converter functions as an APF with harmonic suppression and reactive power compensation to improve the power quality. During grid faults, a hierarchical coordinated control scheme for the generator-side converter, main grid-side converter and auxiliary grid-side converter, depending on the grid voltage sags, is presented to enhance the LVRT capability of the direct-driven PMSG WT. The feasibility and the effectiveness of the proposed system’s topology and hierarchical coordinated control strategy were verified using MATLAB/Simulink simulations.

Comment on “Voltage-Mode All-Pass Filters Including Minimum Component Count Circuits”

OpenAIRE

Lahiri, Abhirup

2009-01-01

This comment is related to the recently published article “Active and Passive Electronic Components” by S. Maheshwari (2007), which presents single current differencing buffered amplifier (CDBA) and current-controlled current differencing buffered amplifier- (CC-CDBA-) based first-order voltage-mode (VM) all-pass filtering (APF) sections. The paper is reviewed, and additional first-order APF realizations have been proposed.

New spatial clustering-based models for optimal urban facility location considering geographical obstacles

Science.gov (United States)

Javadi, Maryam; Shahrabi, Jamal

2014-03-01

The problems of facility location and the allocation of demand points to facilities are crucial research issues in spatial data analysis and urban planning. It is very important for an organization or governments to best locate its resources and facilities and efficiently manage resources to ensure that all demand points are covered and all the needs are met. Most of the recent studies, which focused on solving facility location problems by performing spatial clustering, have used the Euclidean distance between two points as the dissimilarity function. Natural obstacles, such as mountains and rivers, can have drastic impacts on the distance that needs to be traveled between two geographical locations. While calculating the distance between various supply chain entities (including facilities and demand points), it is necessary to take such obstacles into account to obtain better and more realistic results regarding location-allocation. In this article, new models were presented for location of urban facilities while considering geographical obstacles at the same time. In these models, three new distance functions were proposed. The first function was based on the analysis of shortest path in linear network, which was called SPD function. The other two functions, namely PD and P2D, were based on the algorithms that deal with robot geometry and route-based robot navigation in the presence of obstacles. The models were implemented in ArcGIS Desktop 9.2 software using the visual basic programming language. These models were evaluated using synthetic and real data sets. The overall performance was evaluated based on the sum of distance from demand points to their corresponding facilities. Because of the distance between the demand points and facilities becoming more realistic in the proposed functions, results indicated desired quality of the proposed models in terms of quality of allocating points to centers and logistic cost. Obtained results show promising

A distributed data base management facility for the CAD/CAM environment

Science.gov (United States)

Balza, R. M.; Beaudet, R. W.; Johnson, H. R.

1984-01-01

Current/PAD research in the area of distributed data base management considers facilities for supporting CAD/CAM data management in a heterogeneous network of computers encompassing multiple data base managers supporting a variety of data models. These facilities include coordinated execution of multiple DBMSs to provide for administration of and access to data distributed across them.

ICAT: Integrating data infrastructure for facilities based science

International Nuclear Information System (INIS)

Flannery, Damian; Matthews, Brian; Griffin, Tom; Bicarregui, Juan; Gleaves, Michael; Lerusse, Laurent; Downing, Roger; Ashton, Alun; Sufi, Shoaib; Drinkwater, Glen; Kleese van Dam, Kerstin

2009-01-01

ICAT: Integrating data infrastructure for facilities based science Damian Flannery, Brian Matthews, Tom Griffin, Juan Bicarregui, Michael Gleaves, Laurent Lerusse, Roger Downing, Alun Ashton, Shoaib Sufi, Glen Drinkwater, Kerstin Kleese Abstract Scientific facilities, in particular large-scale photon and neutron sources, have demanding requirements to manage the increasing quantities of experimental data they generate in a systematic and secure way. In this paper, we describe the ICAT infrastructure for cataloguing facility generated experimental data which has been in development within STFC and DLS for several years. We consider the factors which have influenced its design and describe its architecture and metadata model, a key tool in the management of data. We go on to give an outline of its current implementation and use, with plans for its future development.

Corrosion behavior of zirconia in acidulated phosphate fluoride

Directory of Open Access Journals (Sweden)

Anie Thomas

2016-02-01

Full Text Available ABSTRACT Objective The corrosion behavior of zirconia in acidulated phosphate fluoride (APF representing acidic environments and fluoride treatments was studied. Material and Methods Zirconia rods were immersed in 1.23% and 0.123% APF solutions and maintained at 37°C for determined periods of time. Surfaces of all specimens were imaged using digital microscopy and scanning electron microscopy (SEM. Sample mass and dimensions were measured for mass loss determination. Samples were characterized by powder X-ray diffraction (XRD to detect changes in crystallinity. A biosensor based on electrochemical impedance spectroscopy (EIS was used to detect ion dissolution of material into the immersion media. Results Digital microscopy revealed diminishing luster of the materials and SEM showed increased superficial corrosion of zirconia submerged in 1.23% APF. Although no structural change was found, the absorption of salts (sodium phosphate onto the surface of the materials bathed in 0.123% APF was significant. EIS indicated a greater change of impedance for the immersion solutions with increasing bathing time. Conclusion Immersion of zirconia in APF solutions showed deterioration limited to the surface, not extending to the bulk of the material. Inferences on zirconia performance in acidic oral environment can be elucidated from the study.

PLC based control system for RAM assembly test facility

International Nuclear Information System (INIS)

Kulkarni, S.S.; Kumar, Vinaya; Chandra, Umesh

1994-01-01

The flexibility, expandability, ease of programming and diagnostic features makes the programmable logic controller (PLC) suitable for a variety of control applications in engineering system test facilities. A PLC based control system for RAM assembly test facility (RATF) and for testing the related hydraulic components is being developed and installed at BARC. This paper describes the approach taken for meeting the control requirements and illustrates the PLC software that has been developed. (author). 1 fig

Fluoride retention in human enamel after a single phosphoric acid and mixed phosphoric acid/SnF2 application in vitro

NARCIS (Netherlands)

Kalter, P.G.E.; Flissebaalje, T.D.; Groeneveld, A.

1980-01-01

Pieces of enamel were treated with either an APF solution or a 1:1 mixture of APF/SnF2 (APF: 1.23 per cent F−, 0.1 M H3PO4; and SnF2: 2 per cent) for 4 min at 37 °C followed by 30 min washing. There was an increase of 1640 parts/106 in the fluoride concentration of APF-treated enamel. Most of the

Nanostructural effect of acid-etching and fluoride application on human primary and permanent tooth enamels

International Nuclear Information System (INIS)

Cheong, Youjin; Choi, Samjin; Kim, So Jung; Park, Hun-Kuk

2012-01-01

This study examined the nanostructural effects of fluoride application and the acid-etching time with respect to the time elapsed after fluoride application on the primary and permanent tooth enamel layers using atomic force microscopy (AFM) and scanning electron microscopy (SEM). 192 non-carious teeth were assigned to sixteen experimental groups (n = 12) including primary (1 to 8) and permanent (9 to 16) teeth, based on the timing of acid-etching with 37% phosphoric acid after an acidulated phosphate fluoride (APF) pre-treatment. The APF pre-treatment led to a decrease in surface roughness in both the primary and permanent teeth. After the APF treatment, the roughness in both primary and permanent teeth increased with the time elapsed. An acid-etching time of 40 s led to increased nanostructural changes in the enamel surfaces compared to the conventional acid-etching time of 20 s. This acid-etching process led to a higher roughness changes in the primary teeth than in the permanent teeth. To obtain proper enamel adhesion of a sealant after APF pre-treatment, it is important to apply acid-etching two weeks after pre-treatment. In addition, the acid-etching time should be prolonged to apply etching more quickly than two weeks, regardless of the primary and permanent teeth. Highlights: ► APF pre-treatment led to decreased surface roughness in the enamel. ► After APF treatment, the more roughness increased with increasing time elapsed. ► Acid-etching should be performed two weeks after fluoride application.

Nanostructural effect of acid-etching and fluoride application on human primary and permanent tooth enamels

Energy Technology Data Exchange (ETDEWEB)

Cheong, Youjin [Department of Biomedical Engineering and Healthcare Industry Research Institute, College of Medicine, Kyung Hee University, Seoul (Korea, Republic of); Choi, Samjin [Department of Biomedical Engineering and Healthcare Industry Research Institute, College of Medicine, Kyung Hee University, Seoul (Korea, Republic of); Department of Orthodontics, College of Dental Medicine, Kyung Hee University, Seoul (Korea, Republic of); Kim, So Jung [Department of Pediatric Dentistry, College of Dental Medicine, Kyung Hee University, Seoul (Korea, Republic of); Park, Hun-Kuk, E-mail: sigmoidus@khu.ac.kr [Department of Biomedical Engineering and Healthcare Industry Research Institute, College of Medicine, Kyung Hee University, Seoul (Korea, Republic of); Program of Medical Engineering, Kyung Hee University, Seoul (Korea, Republic of)

2012-07-01

This study examined the nanostructural effects of fluoride application and the acid-etching time with respect to the time elapsed after fluoride application on the primary and permanent tooth enamel layers using atomic force microscopy (AFM) and scanning electron microscopy (SEM). 192 non-carious teeth were assigned to sixteen experimental groups (n = 12) including primary (1 to 8) and permanent (9 to 16) teeth, based on the timing of acid-etching with 37% phosphoric acid after an acidulated phosphate fluoride (APF) pre-treatment. The APF pre-treatment led to a decrease in surface roughness in both the primary and permanent teeth. After the APF treatment, the roughness in both primary and permanent teeth increased with the time elapsed. An acid-etching time of 40 s led to increased nanostructural changes in the enamel surfaces compared to the conventional acid-etching time of 20 s. This acid-etching process led to a higher roughness changes in the primary teeth than in the permanent teeth. To obtain proper enamel adhesion of a sealant after APF pre-treatment, it is important to apply acid-etching two weeks after pre-treatment. In addition, the acid-etching time should be prolonged to apply etching more quickly than two weeks, regardless of the primary and permanent teeth. Highlights: Black-Right-Pointing-Pointer APF pre-treatment led to decreased surface roughness in the enamel. Black-Right-Pointing-Pointer After APF treatment, the more roughness increased with increasing time elapsed. Black-Right-Pointing-Pointer Acid-etching should be performed two weeks after fluoride application.

A Case Report of Spontaneous Closure of a Posttraumatic Arterioportal Fistula

Directory of Open Access Journals (Sweden)

Hirotada Kittaka

2013-01-01

Full Text Available As the indications for the nonoperative management (NOM of hepatic injury have expanded, the incidence of complications of NOM has increased. Among such complications, arterioportal fistula (APF formation is rare, although dangerous, due to the potential for portal hypertension. Embolization is performed in APF patients with clinical signs suggestive of portal hypertension. Meanwhile, no indications for treatment have been established in APF patients without symptoms, as the natural history of posttraumatic APF is not well understood. We herein report the case of a 35-year-old female with severe hepatic injury (Grade IV on the Organ Injury Scale of the American Association for the Surgery of Trauma due to a traffic accident. Her hemodynamic state remained stable, and an enhanced CT scan obtained on admission showed no extravasation of contrast medium, pseudoaneurysm formation, or APF; therefore, NOM was selected. Although the patient’s physical condition was stable, an enhanced CT scan obtained 13 days after the injury showed APF in segment 8 of the liver. Although embolization was considered, the APF was not accompanied by portal dilatation suggestive of portal hypertension; hence, strict observation was selected. Consequently, follow-up CT performed on day 58 after the injury revealed spontaneous closure of the APF.

Is the closest facility the one actually used? An assessment of travel time estimation based on mammography facilities.

Science.gov (United States)

Alford-Teaster, Jennifer; Lange, Jane M; Hubbard, Rebecca A; Lee, Christoph I; Haas, Jennifer S; Shi, Xun; Carlos, Heather A; Henderson, Louise; Hill, Deirdre; Tosteson, Anna N A; Onega, Tracy

2016-02-18

Characterizing geographic access depends on a broad range of methods available to researchers and the healthcare context to which the method is applied. Globally, travel time is one frequently used measure of geographic access with known limitations associated with data availability. Specifically, due to lack of available utilization data, many travel time studies assume that patients use the closest facility. To examine this assumption, an example using mammography screening data, which is considered a geographically abundant health care service in the United States, is explored. This work makes an important methodological contribution to measuring access--which is a critical component of health care planning and equity almost everywhere. We analyzed one mammogram from each of 646,553 women participating in the US based Breast Cancer Surveillance Consortium for years 2005-2012. We geocoded each record to street level address data in order to calculate travel time to the closest and to the actually used mammography facility. Travel time between the closest and the actual facility used was explored by woman-level and facility characteristics. Only 35% of women in the study population used their closest facility, but nearly three-quarters of women not using their closest facility used a facility within 5 min of the closest facility. Individuals that by-passed the closest facility tended to live in an urban core, within higher income neighborhoods, or in areas where the average travel times to work was longer. Those living in small towns or isolated rural areas had longer closer and actual median drive times. Since the majority of US women accessed a facility within a few minutes of their closest facility this suggests that distance to the closest facility may serve as an adequate proxy for utilization studies of geographically abundant services like mammography in areas where the transportation networks are well established.

Examining controls on peak annual streamflow and floods in the Fraser River Basin of British Columbia

Science.gov (United States)

Curry, Charles L.; Zwiers, Francis W.

2018-04-01

The Fraser River Basin (FRB) of British Columbia is one of the largest and most important watersheds in western North America, and home to a rich diversity of biological species and economic assets that depend implicitly upon its extensive riverine habitats. The hydrology of the FRB is dominated by snow accumulation and melt processes, leading to a prominent annual peak streamflow invariably occurring in May-July. Nevertheless, while annual peak daily streamflow (APF) during the spring freshet in the FRB is historically well correlated with basin-averaged, 1 April snow water equivalent (SWE), there are numerous occurrences of anomalously large APF in below- or near-normal SWE years, some of which have resulted in damaging floods in the region. An imperfect understanding of which other climatic factors contribute to these anomalously large APFs hinders robust projections of their magnitude and frequency. We employ the Variable Infiltration Capacity (VIC) process-based hydrological model driven by gridded observations to investigate the key controlling factors of anomalous APF events in the FRB and four of its subbasins that contribute nearly 70 % of the annual flow at Fraser-Hope. The relative influence of a set of predictors characterizing the interannual variability of rainfall, snowfall, snowpack (characterized by the annual maximum value, SWEmax), soil moisture and temperature on simulated APF at Hope (the main outlet of the FRB) and at the subbasin outlets is examined within a regression framework. The influence of large-scale climate modes of variability (the Pacific Decadal Oscillation (PDO) and the El Niño-Southern Oscillation - ENSO) on APF magnitude is also assessed, and placed in context with these more localized controls. The results indicate that next to SWEmax (univariate Spearman correlation with APF of ρ ^ = 0.64; 0.70 (observations; VIC simulation)), the snowmelt rate (ρ ^ = 0.43 in VIC), the ENSO and PDO indices (ρ ^ = -0.40; -0.41) and (�

Cost effectiveness of facility and home based HIV voluntary ...

African Journals Online (AJOL)

Cost effectiveness of facility and home based HIV voluntary counseling and ... Background: In Uganda, the main stay for provision of human immunodeficiency virus (HIV) voluntary counseling and testing (VCT) ... AJOL African Journals Online.

Comparing the nutrition environment and practices of home- and centre-based child-care facilities.

Science.gov (United States)

Martyniuk, Olivia J M; Vanderloo, Leigh M; Irwin, Jennifer D; Burke, Shauna M; Tucker, Patricia

2016-03-01

To assess and compare the nutrition environment and practices (as they relate to pre-schoolers) of centre- and home-based child-care facilities. Using a cross-sectional study design, nineteen child-care facilities (ten centre-based, nine home-based) were assessed for one full day using the Environment and Policy Assessment and Observation (EPAO) tool (consisting of a day-long observation/review of the nutrition environment, practices and related documents). Specifically, eight nutrition-related subscales were considered. Child-care facilities in London, Ontario, Canada. Child-care facilities were recruited through directors at centre-based programmes and the providers of home-based programmes. The mean total nutrition environment EPAO scores for centre- and home-based facilities were 12·3 (sd 1·94) and 10·8 (sd 0·78) out of 20 (where a higher score indicates a more supportive environment with regard to nutrition), respectively. The difference between the total nutrition environment EPAO score for centre- and home-based facilities was approaching significance (P=0·055). For both types of facilities, the highest nutrition subscale score (out of 20) was achieved in the staff behaviours domain (centre mean=17·4; home mean=17·0) and the lowest was in the nutrition training and education domain (centre mean=3·6; home mean=2·0). Additional research is needed to confirm these findings. In order to better support child-care staff and enhance the overall nutrition environment in child care, modifications to food practices could be adopted. Specifically, the nutritional quality of foods/beverages provided to pre-schoolers could be improved, nutrition-related training for child-care staff could be provided, and a nutrition curriculum could be created to educate pre-schoolers about healthy food choices.

A US Based Ultrafast Interdisciplinary Research Facility

Science.gov (United States)

Gueye, Paul; Hill, Wendell; Johnson, Anthony

2006-10-01

The US scientific competitiveness on the world arena has substantially decreased due to the lack of funding and training of qualified personnel. Most of the potential workforce found in higher education is composed of foreign students and post-docs. In the specific field of low- and high-field science, the European and Asian communities are rapidly catching-up with the US, even leading in some areas. To remain the leader in ultrafast science and technology, new visions and commitment must be embraced. For that reason, an international effort of more than 70 countries for a US-based interdisciplinary research facility using ultrafast laser technology is under development. It will provide research and educational training, as well as new venues for a strong collaboration between the fields of astrophysics, nuclear/high energy physics, plasma physics, optical sciences, biological and medical physics. This facility will consist of a uniquely designed high contrast multi-lines concept housing twenty experimental rooms shared between four beams:[0.1 TW, 1 kHz], [10 TW, 9 kHz], [100-200 TW, 10 Hz] and [500 TW, 10 Hz]. The detail schematic of this multi-laser system, foreseen research and educational programs, and organizational structure of this facility will be presented.

Charles L. Brewer Award for Distinguished Teaching of Psychology: Neil Lutsky

Science.gov (United States)

American Psychologist, 2011

2011-01-01

The American Psychological Foundation (APF) Charles L. Brewer Award for Distinguished Teaching of Psychology recognizes an outstanding career contribution to the teaching of psychology. The 2011 recipient of the Distinguished Teaching Award is Neil Lutsky. Dorothy W. Cantor, president of the APF, will present the APF Distinguished Teaching Award…

Power quality issues current harmonics

CERN Document Server

Mikkili, Suresh

2015-01-01

Power Quality Issues: Current Harmonics provides solutions for the mitigation of power quality problems related to harmonics. Focusing on active power filters (APFs) due to their excellent harmonic and reactive power compensation in two-wire (single phase), three-wire (three-phase without neutral), and four-wire (three-phase with neutral) AC power networks with nonlinear loads, the text:Introduces the APF technology, describing various APF configurations and offering guidelines for the selection of APFs for specific application considerationsCompares shunt active filter (SHAF) control strategi

A performance goal-based seismic design philosophy for waste repository facilities

International Nuclear Information System (INIS)

Hossain, Q.A.

1994-02-01

A performance goal-based seismic design philosophy, compatible with DOE's present natural phenomena hazards mitigation and ''graded approach'' philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed

Charles L. Brewer Award for Distinguished Teaching of Psychology

Science.gov (United States)

American Psychologist, 2009

2009-01-01

The American Psychological Foundation (APF) Charles L. Brewer Distinguished Teaching of Psychology Award recognizes an outstanding career contribution to the teaching of psychology. The 2009 recipient of the Distinguished Teaching Award is William Buskist. Dorothy W. Cantor, president of the APF, will present the APF Teaching Award at the 117th…

Fixed Base Modal Testing Using the NASA GRC Mechanical Vibration Facility

Science.gov (United States)

Staab, Lucas D.; Winkel, James P.; Suarez, Vicente J.; Jones, Trevor M.; Napolitano, Kevin L.

2016-01-01

The Space Power Facility at NASA's Plum Brook Station houses the world's largest and most powerful space environment simulation facilities, including the Mechanical Vibration Facility (MVF), which offers the world's highest-capacity multi-axis spacecraft shaker system. The MVF was designed to perform sine vibration testing of a Crew Exploration Vehicle (CEV)-class spacecraft with a total mass of 75,000 pounds, center of gravity (cg) height above the table of 284 inches, diameter of 18 feet, and capability of 1.25 gravity units peak acceleration in the vertical and 1.0 gravity units peak acceleration in the lateral directions. The MVF is a six-degree-of-freedom, servo-hydraulic, sinusoidal base-shake vibration system that has the advantage of being able to perform single-axis sine vibration testing of large structures in the vertical and two lateral axes without the need to reconfigure the test article for each axis. This paper discusses efforts to extend the MVF's capabilities so that it can also be used to determine fixed base modes of its test article without the need for an expensive test-correlated facility simulation.

A performance goal-based seismic design philosophy for waste repository facilities

International Nuclear Information System (INIS)

Hossain, Q.A.

1994-01-01

A performance goal-based seismic design philosophy, compatible with DOE's present natural phenomena hazards mitigation and open-quotes graded approachclose quotes philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed

Centralized computer-based controls of the Nova Laser Facility

International Nuclear Information System (INIS)

Krammen, J.

1985-01-01

This article introduces the overall architecture of the computer-based Nova Laser Control System and describes its basic components. Use of standard hardware and software components ensures that the system, while specialized and distributed throughout the facility, is adaptable. 9 references, 6 figures

Enhanced photosynthetic capacity increases nitrogen metabolism through the coordinated regulation of carbon and nitrogen assimilation in Arabidopsis thaliana.

Science.gov (United States)

Otori, Kumi; Tanabe, Noriaki; Maruyama, Toshiki; Sato, Shigeru; Yanagisawa, Shuichi; Tamoi, Masahiro; Shigeoka, Shigeru

2017-09-01

Plant growth and productivity depend on interactions between the metabolism of carbon and nitrogen. The sensing ability of internal carbon and nitrogen metabolites (the C/N balance) enables plants to regulate metabolism and development. In order to investigate the effects of an enhanced photosynthetic capacity on the metabolism of carbon and nitrogen in photosynthetically active tissus (source leaves), we herein generated transgenic Arabidopsis thaliana plants (ApFS) that expressed cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase in their chloroplasts. The phenotype of ApFS plants was indistinguishable from that of wild-type plants at the immature stage. However, as plants matured, the growth of ApFS plants was superior to that of wild-type plants. Starch levels were higher in ApFS plants than in wild-type plants at 2 and 5 weeks. Sucrose levels were also higher in ApFS plants than in wild-type plants, but only at 5 weeks. On the other hand, the contents of various free amino acids were lower in ApFS plants than in wild-type plants at 2 weeks, but were similar at 5 weeks. The total C/N ratio was the same in ApFS plants and wild-type plants, whereas nitrite levels increased in parallel with elevations in nitrate reductase activity at 5 weeks in ApFS plants. These results suggest that increases in the contents of photosynthetic intermediates at the early growth stage caused a temporary imbalance in the free-C/free-N ratio and, thus, the feedback inhibition of the expression of genes involved in the Calvin cycle and induction of the expression of those involved in nitrogen metabolism due to supply deficient free amino acids for maintenance of the C/N balance in source leaves of ApFS plants.

The Relationship between Facility-Based Delivery and Infant Immunization in sub-Saharan Africa.

Science.gov (United States)

Moyer, Cheryl A; Benyas, Dana; Rominski, Sarah

2016-06-01

This study explored the relationship between facility-based delivery and infant immunizations in sub-Saharan Africa, controlling for economic development indicators. Publically available data were collected and imported into Stata 11.0 for descriptive, correlation, and regression analyses. Facility delivery was significantly associated with full vaccination and BCG immunization in children aged 12-23 months. Facility delivery was associated with full vaccination (phealthcare system.

Estimation and reduction of harmonic currents from power converters

DEFF Research Database (Denmark)

Asiminoaei, Lucian

-based method depends very much on the amount and accuracy of collected data in the development stage. The outcome of this investigation is a Harmonic Calculation Software compiled into a Graphical User Interface PC-software application, which can be applied for fast estimations of the harmonic currents...... control of the proposed topologies are given together with laboratory tests. One harmonic current mitigation solution found is to connect (two) smaller power APF's in parallel, sharing the same ac- and dc-bus. It is proven that parallel APF's may have lower passive components although other issues arises......, like circulation currents, which is removed here by common mode coils. Another harmonic solution is to use cascade connection of (two) independent APF's that cooperatively share the task of the harmonic mitigation. Two cooperative control methods are proposed called load-sharing and harmonic-sharing...

Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility

Science.gov (United States)

Williamson, Nicholas A.

2018-03-01

This paper discusses the successful adoption of a subscription-based, open-access model of service delivery for a mass spectrometry and proteomics facility. In 2009, the Mass Spectrometry and Proteomics Facility at the University of Melbourne (Australia) moved away from the standard fee for service model of service provision. Instead, the facility adopted a subscription- or membership-based, open-access model of service delivery. For a low fixed yearly cost, users could directly operate the instrumentation but, more importantly, there were no limits on usage other than the necessity to share available instrument time with all other users. All necessary training from platform staff and many of the base reagents were also provided as part of the membership cost. These changes proved to be very successful in terms of financial outcomes for the facility, instrument access and usage, and overall research output. This article describes the systems put in place as well as the overall successes and challenges associated with the operation of a mass spectrometry/proteomics core in this manner. [Figure not available: see fulltext.

Beta Beams: an accelerator based facility to explore Neutrino oscillation physics

CERN Document Server

Wildner, E; Hansen, C; De Melo Mendonca, T; Stora, T; Payet, J; Chance, A; Zorin, V; Izotov, I; Rasin, S; Sidorov, A; Skalyga, V; De Angelis, G; Prete, G; Cinausero, M; Kravchuk, VL; Gramegna, F; Marchi, T; Collazuol, G; De Rosa, G; Delbar, T; Loiselet, M; Keutgen, T; Mitrofanov, S; Lamy, T; Latrasse, L; Marie-Jeanne, M; Sortais, P; Thuillier, T; Debray, F; Trophime, C; Hass, M; Hirsh, T; Berkovits, D; Stahl, A

2011-01-01

The discovery that the neutrino changes flavor as it travels through space has implications for the Standard Model of particle physics (SM)[1]. To know the contribution of neutrinos to the SM, needs precise measurements of the parameters governing the neutrino oscillations. This will require a high intensity beam-based neutrino oscillation facility. The EURONu Design Study will review three currently accepted methods of realizing this facility (the so-called Super-Beams, Beta Beams and Neutrino Factories) and perform a cost assessment that, coupled with the physics performance, will give means to the European research authorities to make a decision on the layout and construction of the future European neutrino oscillation facility. ”Beta Beams” produce collimated pure electron neutrino and antineutrino beams by accelerating beta active ions to high energies and letting them decay in a race-track shaped storage ring. EURONu Beta Beams are based on CERNs infrastructure and the fact that some of the already ...

Particulate hot gas stream cleanup technical issues

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

This is the eleventh in a series of quarterly reports describing the activities performed under Contract No. DE-AC21-94MC31160. Analyses of Hot Gas Stream Cleanup (HGCU) ashes and descriptions of filter performance address aspects of filter operation that are apparently linked to the characteristics of the collected ash or the performance of the ceramic bed filter elements. Task 1 is designed to generate a data base of the key characteristics of ashes collected from operating advanced particle filters (APFS) and to relate these ash properties to the operation and performance of these filters. Task 2 concerns testing and failure analysis of ceramic filter elements. Under Task 1 during the past quarter, analyses were completed on samples obtained during a site visit to the Power Systems Development Facility (PSDF). Analyses are in progress on ash samples from the Advanced Particulate Filter (APF) at the Pressurized Fluidized-Bed Combustor (PFBC) that was in operation at Tidd and ash samples from the Pressurized Circulating Fluid Bed (PCFB) system located at Karhula, Finland. An additional analysis was performed on a particulate sample from the Transport Reactor Demonstration Unit (TRDU) located at the University of North Dakota Energy and Environmental Research Center. A manuscript and poster were prepared for presentation at the Advanced Coal-Based Power and Environmental Systems `97 Conference scheduled for July 22 - 24, 1997. A summary of recent project work covering the mechanisms responsible for ash deposit consolidation and ash bridging in APF`s collecting PFB ash was prepared and presented at FETC-MGN in early July. The material presented at that meeting is included in the manuscript prepared for the Contractor`s Conference and also in this report. Task 2 work during the past quarter included mechanical testing and microstructural examination of Schumacher FT20 and Pall 326 as- manufactured, after 540 hr in service at Karhula, and after 1166 hr in service at

A case series study on the effect of Ebola on facility-based deliveries in rural Liberia.

Science.gov (United States)

Lori, Jody R; Rominski, Sarah Danielson; Perosky, Joseph E; Munro, Michelle L; Williams, Garfee; Bell, Sue Anne; Nyanplu, Aloysius B; Amarah, Patricia N M; Boyd, Carol J

2015-10-12

As communities' fears of Ebola virus disease (EVD) in West Africa exacerbate and their trust in healthcare providers diminishes, EVD has the potential to reverse the recent progress made in promoting facility-based delivery. Using retrospective data from a study focused on maternal and newborn health, this analysis examined the influence of EVD on the use of facility-based maternity care in Bong Country, Liberia, which shares a boarder with Sierra Leone - near the epicenter of the outbreak. Using a case series design, retrospective data from logbooks were collected at 12 study sites in one county. These data were then analyzed to determine women's use of facility-based maternity care between January 2012 and October 2014. The primary outcome was the number of facility-based deliveries over time. The first suspected case of EVD in Bong County was reported on June 30, 2014. Heat maps were generated and the number of deliveries was normalized to the average number of deliveries during the full 12 months before the EVD outbreak (March 2013 - February 2014). Prior to the EVD outbreak, facility-based deliveries steadily increased in Bong County reaching an all-time high of over 500 per month at study sites in the first half of 2014 - indicating Liberia was making inroads in normalizing institutional maternal healthcare. However, as reports of EVD escalated, facility-based deliveries decreased to a low of 113 in August 2014. Ebola virus disease has negatively impacted the use of facility-based maternity services, placing childbearing women at increased risk for morbidity and death.

Development of Strategic Technology Road map for Establishing Safety Infrastructure of Fusion Energy

International Nuclear Information System (INIS)

Han, B. S.; Cho, S. H.; Kam, S. C.; Kim, K. T.

2009-01-01

The Korean Government established an 'Act for the Promotion of Fusion Energy Development (APFED)' and formulated a 'Strategy Promotion Plan for Fusion Energy Development.' KINS has carried out a safety review of KSTAR (Korea Superconducting Tokamak Advanced Research), for which an application for use was received in 2002 and the license was issued in August 2007. With respect to the APFED, 'Atomic Energy Acts (AEAs)' shall apply in the fusion safety regulation. However the AEAs are not applicable because they aim for dealing with nuclear energy. In this regard, this study was planned to establish safety infrastructure for fusion energy and to develop technologies necessary for verifying the safety. The purpose of this study is to develop a 'Strategic Technology Roadmap (STR) for establishing safety infrastructure of the fusion energy', which displays the content and development schedule and strategy for developing the laws, safety goals and principles, and safety standards applicable for fusion safety regulation, and core technology required for safety regulation of fusion facilities

Examining school-based hygiene facilities: a quantitative assessment in a Ghanaian municipality.

Science.gov (United States)

Appiah-Brempong, Emmanuel; Harris, Muriel J; Newton, Samuel; Gulis, Gabriel

2018-05-02

The crucial role of adequate water, sanitation and hygiene (WASH) facilities in influencing children's handwashing behaviour is widely reported. Report from UNICEF indicates a dearth of adequate data on WASH facilities in schools, especially in the developing world. This study sought to contribute to building the evidence-base on school hygiene facilities in Ghana. The study further explored for possible associations and differences between key variables within the context of school water, sanitation and hygiene. Data was collected from 37 junior high schools using an observational checklist. Methods of data analysis included a Scalogram model, Fisher's exact test, and a Student's t-test. Results of the study showed a facility deficiency in many schools: 33% of schools had students washing their hands in a shared receptacle (bowl), 24% had students using a single cotton towel to dry hands after handwashing, and only 16% of schools had a functional water facility. Furthermore, results of a proportion test indicated that 83% of schools which had functional water facilities also had functional handwashing stations. On the other hand, only 3% of schools which had functional water facilities also had a functional handwashing stations. A test of difference in the proportions of the two sets of schools showed a statistically significant difference (p facilities would be timely.

Qualification of academic facilities for small-scale automated manufacture of autologous cell-based products.

Science.gov (United States)

Hourd, Paul; Chandra, Amit; Alvey, David; Ginty, Patrick; McCall, Mark; Ratcliffe, Elizabeth; Rayment, Erin; Williams, David J

2014-01-01

Academic centers, hospitals and small companies, as typical development settings for UK regenerative medicine assets, are significant contributors to the development of autologous cell-based therapies. Often lacking the appropriate funding, quality assurance heritage or specialist regulatory expertise, qualifying aseptic cell processing facilities for GMP compliance is a significant challenge. The qualification of a new Cell Therapy Manufacturing Facility with automated processing capability, the first of its kind in a UK academic setting, provides a unique demonstrator for the qualification of small-scale, automated facilities for GMP-compliant manufacture of autologous cell-based products in these settings. This paper shares our experiences in qualifying the Cell Therapy Manufacturing Facility, focusing on our approach to streamlining the qualification effort, the challenges, project delays and inefficiencies we encountered, and the subsequent lessons learned.

Facilities inventory protection for nuclear facilities

International Nuclear Information System (INIS)

Schmitt, F.J.

1989-01-01

The fact that shut-down applications have been filed for nuclear power plants, suggests to have a scrutinizing look at the scopes of assessment and decision available to administrations and courts for the protection of facilities inventories relative to legal and constitutional requirements. The paper outlines the legal bases which need to be observed if purposeful calculation is to be ensured. Based on the different actual conditions and legal consequences, the author distinguishes between 1) the legal situation of facilities licenced already and 2) the legal situation of facilities under planning during the licencing stage. As indicated by the contents and restrictions of the pertinent provisions of the Atomic Energy Act and by the corresponding compensatory regulation, the object of the protection of facilities inventor in the legal position of the facility owner within the purview of the Atomic Energy Act, and the licensing proper. Art. 17 of the Atomic Energy Act indicates the legislators intent that, once issued, the licence will be the pivotal point for regulations aiming at protection and intervention. (orig./HSCH) [de

Use of base isolation techniques for the design of high-level waste storage facility enclosure at INEL

International Nuclear Information System (INIS)

Vallenas, J.M.; Wong, Chun K.; Beer, M.J.

1993-08-01

Current Department of Energy criteria for facilities subjected to natural hazards provide guidelines to place facilities or portions of facilities into usage categories. Usage categories are based on characteristics such as mission dependence, type of hazardous materials involved, and performance goals. Seismic requirements are significantly more stringent for facilities falling into higher ''hazard facility use categories''. A special problem arises in cases where a facility or portion of a facility is dependent on another facility of lower ''hazard facility use category'' for support or protection. Creative solutions can minimize the cost Unpact of ensuring that the lower category item does not compromise the performance of the higher category item. In this paper, a base isolation solution is provided for a ''low hazard facility use category'' weather enclosure designed so it will not collapse onto a ''high hazard facility use category'' high level waste storage facility at INEL. This solution is compared to other more conventional procedures. Details, practical limitations, licensing and regulatory considerations, and cost comparisons are provided

Health physics and quality control management of a cyclotron-based PET facility

International Nuclear Information System (INIS)

Jerabek, P.A.

1995-01-01

This paper provides an overview of the operation and management of a Positron Emission Tomography (PET) facility at the University of Texas. The facility components are discussed from an operations perspective with an emphasis on devices, and on practices and procedures which are implemented to ensure that personnel exposures are as low as reasonably achievable. The cyclotron-based PET facility uses in-house production of PET radioisotopes for preparation of radiopharmaceuticals. A combination of specially designed cyclotron equipped devices, radiopharmaceutical preparation devices, and shielded devices along with health physics practices have helped to make PET operations become routine

Ecdysone-dependent and ecdysone-independent programmed cell death in the developing optic lobe of Drosophila.

Science.gov (United States)

Hara, Yusuke; Hirai, Keiichiro; Togane, Yu; Akagawa, Hiromi; Iwabuchi, Kikuo; Tsujimura, Hidenobu

2013-02-01

The adult optic lobe of Drosophila develops from the primordium during metamorphosis from mid-3rd larval stage to adult. Many cells die during development of the optic lobe with a peak of the number of dying cells at 24 h after puparium formation (h APF). Dying cells were observed in spatio-temporal specific clusters. Here, we analyzed the function of a component of the insect steroid hormone receptor, EcR, in this cell death. We examined expression patterns of two EcR isoforms, EcR-A and EcR-B1, in the optic lobe. Expression of each isoform altered during development in isoform-specific manner. EcR-B1 was not expressed in optic lobe neurons from 0 to 6h APF, but was expressed between 9 and 48 h APF and then disappeared by 60 h APF. In each cortex, its expression was stronger in older glia-ensheathed neurons than in younger ones. EcR-B1 was also expressed in some types of glia. EcR-A was expressed in optic lobe neurons and many types of glia from 0 to 60 h APF in a different pattern from EcR-B1. Then, we genetically analyzed EcR function in the optic lobe cell death. At 0 h APF, the optic lobe cell death was independent of any EcR isoforms. In contrast, EcR-B1 was required for most optic lobe cell death after 24 h APF. It was suggested that cell death cell-autonomously required EcR-B1 expressed after puparium formation. βFTZ-F1 was also involved in cell death in many dying-cell clusters, but not in some of them at 24 h APF. Altogether, the optic lobe cell death occurred in ecdysone-independent manner at prepupal stage and ecdysone-dependent manner after 24 h APF. The acquisition of ecdysone-dependence was not directly correlated with the initiation or increase of EcR-B1 expression. Copyright © 2012 Elsevier Inc. All rights reserved.

Combination of active components of Xiexin decoction ameliorates renal fibrosis through the inhibition of NF-κB and TGF-β1/Smad pathways in db/db diabetic mice.

Directory of Open Access Journals (Sweden)

Jia-Sheng Wu

Full Text Available Xiexin decoction, a herbal therapeutic agent commonly used in traditional Chinese medicine, is recognized for its beneficial effects on diabetic nephropathy exerted through the combined action of multiple components, including Rhizoma Coptidis alkaloids (A, Radix et Rhizoma Rhei polysaccharides (P, and Radix Scutellaria flavones (F. Our previous studies have shown that a combination of A, P, and F (APF exhibits renoprotective effects against diabetic nephropathy. This study was aimed at determining the effects of APF on renal fibrosis in diabetic nephropathy and elucidating the underlying molecular mechanisms. To evaluate the effects of APF, in vivo, db/db diabetic mice were orally administered a low or high dose of APF (300 or 600 mg/kg, respectively once a day for 8 weeks. We evaluated the blood and urine indices of metabolic and renal function, renal tissue histopathology, renal inflammation, and fibrosis. APF treatment significantly ameliorated glucose and lipid metabolism dysfunction, decreased urinary albumin excretion, normalized creatinine clearance, and reduced the morphological changes in renal tissue. Additionally, APF administration in db/db diabetic mice reduced the elevated levels of renal inflammation mediators such as intercellular adhesion molecule-1, monocyte chemotactic protein-1, tumor necrosis factor-α, interleukin-1β, and active nuclear factor κB (NF-κB. APF treatment also reduced type I and IV collagen, transforming growth factor-β1 (TGF-β1, and TGF-β1 type II receptor expression levels, and decreased the phosphorylation of Smad2/3 in the kidneys of db/db diabetic mice. These results suggest that APF reduces renal fibrosis in diabetic nephropathy through the NF-κB and TGF-β1/Smad signaling pathways. In vitro, APF treatment reduced cell proliferation and protein expression of α-smooth muscle actin, collagen I, TGF-β1 and NF-κB in mesangial cells cultured with high glucose concentrations. Our findings indicate

Facilities Performance Indicators Report 2013-14: Tracking Your Facilities Vital Signs

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2015

2015-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA: Association of Higher Education Facilities Officers (APPA's) Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance…

A DC-Link Voltage Self-Balance Method for a Diode-Clamped Modular Multilevel Converter With Minimum Number of Voltage Sensors

DEFF Research Database (Denmark)

Gao, Congzhe; Jiang, Xinjian; Li, Yongdong

2013-01-01

Voltage balance issue of dc-link capacitors is very important for applications of a cascade multilevel converter or a modular multilevel converter. In this paper, a novel diode-clamped modular multilevel converter (DCM2C) topology is proposed and a power feedback control method is developed...... used traditional method; therefore, the system performance improvement and cost reduction are expected. Based on the proposed DCM2C, a novel N +1-level cascade multilevel topology is proposed for a cascade active power filter (CS-APF). The simulation and experimental results from the CS-APF have...

A grid-voltage-sensorless resistive active power filter with series LC-filter

DEFF Research Database (Denmark)

Bai, Haofeng; Wang, Xiongfei; Blaabjerg, Frede

2017-01-01

Voltage-sensorless control has been investigated for Voltage Source Inverters (VSIs) for many years due to the reduced system cost and potentially improved system reliability. The VSI based Resistive Active Power Filters (R-APFs) are now widely used to prevent the harmonic resonance in power...... distribution network, for which the voltage sensors are needed in order to obtain the current reference. In this paper a grid-voltage-sensorless control strategy is proposed for the R-APF with series LC-filter. Unlike the traditional resistance emulation method, this proposed control method re...

A Grid-Voltage-Sensorless Resistive Active Power Filter with Series LC-Filter

DEFF Research Database (Denmark)

Bai, Haofeng; Wang, Xiongfei; Blaabjerg, Frede

2018-01-01

Voltage-sensorless control has been investigated for Voltage Source Inverters (VSIs) for many years due to the reduced system cost and potentially improved system reliability. The VSI based Resistive Active Power Filters (R-APFs) are now widely used to prevent the harmonic resonance in power...... distribution network, for which the voltage sensors are needed in order to obtain the current reference. In this paper a grid-voltage-sensorless control strategy is proposed for the R-APF with series LC-filter. Unlike the traditional resistance emulation method, this proposed control method re...

Simultaneous EEG and EMG biofeedback for peak performance in musicians.

Science.gov (United States)

Markovska-Simoska, Silvana; Pop-Jordanova, Nada; Georgiev, Dejan

2008-07-01

The aim of this study was to determine the effects of alpha neurofeedback and EMG biofeedback protocols for improvement of musical performance in violinists. The sample consisted of 12 music students (10 violinists and 2 viola players) from the Faculty of Music, Skopje (3 males, mean age of 20 +/- 0 and 9 females, mean age = 20.89 +/- 2.98). Six of them had a low alpha peak frequency (APF) ( 10 Hz). The sample was randomized in two groups. The students from the experimental group participated in 20 sessions of biofeedback (alpha/EMG), combined with music practice, while the students from the control group did only music practice. Average absolute power, interhemispheric coherence in the alpha band, alpha peak frequency (APF), individual alpha band width (IABW), amount of alpha suppression (AAS) and surface forehead integrated EMG power (IEMG), as well as a score on musical performance and inventories measuring anxiety, were assessed. Alpha-EEG/EMG-biofeedback was associated with a significant increase in average alpha power, APF and IABW in all the participants and with decreases in IEMG only in high-APF musicians. The biofeedback training success was positively correlated with the alpha power, IcoH, APF, IABW and baseline level of APF and IABW. Alpha-EEG/EMG biofeedback is capable of increasing voluntary self-regulation and the quality of musical performance. The efficiency of biofeedback training depends on the baseline EEG alpha activity status, in particular the APF.

Developing tourism facilities based on geotourism in Silalahi Village, Geopark Toba Caldera

Science.gov (United States)

Ginting, Nurlisa; Sasmita, Anggun

2018-03-01

Toba Caldera is one of the biggest lakes in Indonesia with supervolcano geology phenomenon, and its result amazing natural resources. It makes Toba Lake become the number one tourism in North Sumatera. However, tourism in Toba Lake is still needed development. Geotourism is one of the concept that suitable for this case. It is because geotourism is a new development tourism concept that focuses on the natural and geological phenomenon. Silalahi Village is one of the areas in Toba Caldera that still needs development, especially in tourism facilities sector. This research aims to investigation the facilities concept based on geotourism in Silalahi Village that would be analyzed by three element of tourism facilities namely, accommodation, support facilities and tourism auxiliary facilities. The method used for this research is mixed methods by distributing 100 questionnaires, observations directly to the area and interviews with three informants related parties interested in tourism, such as local people, government, and academics. The data would be processed and analyzed with techniques of exploration. The result shows that the three elements of tourism facilities are still lacking and needs to improve to increase the economy and tourism in the area.

Congenital, solitary, large, intrahepatic arterioportal fistula in a child: management and review of the literature

Energy Technology Data Exchange (ETDEWEB)

Kumar, Nagappan; de Ville de Goyet, Jean; Sharif, Khalid; McKiernan, Patrick [Liver Unit, Birmingham Children' s Hospital NHS Trust, Steelhouse Lane, Birmingham B4 6NH (United Kingdom); John, Philip [Department of Radiology, Birmingham Children' s Hospital NHS Trust, Birmingham (United Kingdom)

2003-01-01

Congenital intrahepatic arterioportal fistula (APF) is a rare condition. In most cases, the symptoms and complications develop during infancy. We report here the incidental finding of a large and solitary congenital APF in a 13-year-old boy, with subsequent related clinical complications. At angiography, an APF connecting the left hepatic artery and the left branch of the portal vein (PV) was demonstrated with reversed flow in the left and main PV. The fistula was successfully occluded, in a single embolisation session, using an Amplatzer occlusion device. This was associated with immediate restoration of normal hepatopetal flow in the PV and followed by resolution of the clinical signs of portal hypertension. This patient is the oldest child with congenital intrahepatic APF to be reported. We emphasise the interest of using a large device (Amplatzer) to occlude a solitary large APF in a single session and, more importantly, to avoid other possible complications related to embolisation. (orig.)

Determining perception-based impacts of noxious facilities on wage rates and property values

Energy Technology Data Exchange (ETDEWEB)

Nieves, L.A.; Clark, D.E.

1992-02-01

This document, written for the US Department of Energy, discusses current information and the need for future research on estimating the impacts on wages and property values that could result from people's perceptions of the risks associated with noxious facilities. Psychometric studies indicate that the US population is averse to living near noxious facilities, nuclear-related facilities in particular. Contingent valuation and hedonic studies find that the net economic impacts of proximity to noxious facilities are generally negative and often substantial. Most of these studies are limited in scope, and none estimate the impacts derived from public perceptions of such facilities. This study examines the mechanisms by which negative public perceptions result in economic impacts reflected in wages and property values. On the basis of these mechanisms, it develops a predictive model of perception-based impacts and identifies the data and methods needed to implement it. The key to predicting perception-based impacts lies in combining psychometric and hedonic methods. The reliability of psychometric measures as indicators of aversive stimuli that precipitate economic impacts can be empirically tested. To test the robustness of the findings, alternative estimation methods an be employed in the hedonic analysis. Contingent valuation methods can confirm the results.

Determining perception-based impacts of noxious facilities on wage rates and property values

Energy Technology Data Exchange (ETDEWEB)

Nieves, L.A.; Clark, D.E.

1992-02-01

This document, written for the US Department of Energy, discusses current information and the need for future research on estimating the impacts on wages and property values that could result from people`s perceptions of the risks associated with noxious facilities. Psychometric studies indicate that the US population is averse to living near noxious facilities, nuclear-related facilities in particular. Contingent valuation and hedonic studies find that the net economic impacts of proximity to noxious facilities are generally negative and often substantial. Most of these studies are limited in scope, and none estimate the impacts derived from public perceptions of such facilities. This study examines the mechanisms by which negative public perceptions result in economic impacts reflected in wages and property values. On the basis of these mechanisms, it develops a predictive model of perception-based impacts and identifies the data and methods needed to implement it. The key to predicting perception-based impacts lies in combining psychometric and hedonic methods. The reliability of psychometric measures as indicators of aversive stimuli that precipitate economic impacts can be empirically tested. To test the robustness of the findings, alternative estimation methods an be employed in the hedonic analysis. Contingent valuation methods can confirm the results.

The Effect of Casein Phosphopeptide-Amorf Calcium Phosphate and Acidulated Phosphate Fluoride Gel on Dental Erosion in Primary Teeth: An in Vitro Study.

Science.gov (United States)

Maden, Eda Arat; Acar, Özge; Altun, Ceyhan; Polat, Günseli Güven

This study aimed to investigate the effect of acidulated phosphate fluoride (APF) gel and casein phosphopeptide/amorphous calciumphosphate (CPP-ACP) on the dental erosion produced by carbonated soft drink in primary teeth. This study evaluated by an in vitro model the effect of APF gel and CPP-ACP on the dental enamel previously subjected to erosive challenge with carbonated soft drink. Sixty sound human primary molars were prepared by embedding the crown sections in acrylic resin blocks leaving the enamel surfaces exposed. The surface roughness of the enamel was measured with prophilometry at baseline. Specimens were randomly divided into three treatment groups (n:20): artificial saliva, CPP-ACP, 1.23% APF gel. All specimens were then exposed to an erosive challenge of carbonated soft drink and artificial saliva for 20 cycles of 20 seconds each. Demineralization-remineralization cycles was repeated twice at eight-hour intervals and roughness values were measured. Enamel samples were treated with artificial saliva, CPP-ACP, 1.23% APF gel applied for 10 min after erosive challenge. The arithmetic average roughness (Ra) readings were recorded after remineralization agents were applied. The mean surface roughness in all groups increased significantly after erosion process and decreased after remineralization treatment. After treatment, the mean surface roughness of the 1.23% APF gel group was significantly less than the other groups and the mean surface roughness of the artificial saliva group was significantly more than the other groups. 1.23% APF gel showed the highest protective effect against erosive enamel loss. Under the conditions of this study, artificial saliva, CPP-ACP and 1.23% APF treatments were able to reduce erosive enamel loss produced by carbonated soft drink in primary teeth. However, 1.23% APF gel showed the highest protective effect against erosive enamel loss.

Examining controls on peak annual streamflow and floods in the Fraser River Basin of British Columbia

Directory of Open Access Journals (Sweden)

C. L. Curry

2018-04-01

Full Text Available The Fraser River Basin (FRB of British Columbia is one of the largest and most important watersheds in western North America, and home to a rich diversity of biological species and economic assets that depend implicitly upon its extensive riverine habitats. The hydrology of the FRB is dominated by snow accumulation and melt processes, leading to a prominent annual peak streamflow invariably occurring in May–July. Nevertheless, while annual peak daily streamflow (APF during the spring freshet in the FRB is historically well correlated with basin-averaged, 1 April snow water equivalent (SWE, there are numerous occurrences of anomalously large APF in below- or near-normal SWE years, some of which have resulted in damaging floods in the region. An imperfect understanding of which other climatic factors contribute to these anomalously large APFs hinders robust projections of their magnitude and frequency. We employ the Variable Infiltration Capacity (VIC process-based hydrological model driven by gridded observations to investigate the key controlling factors of anomalous APF events in the FRB and four of its subbasins that contribute nearly 70 % of the annual flow at Fraser-Hope. The relative influence of a set of predictors characterizing the interannual variability of rainfall, snowfall, snowpack (characterized by the annual maximum value, SWEmax, soil moisture and temperature on simulated APF at Hope (the main outlet of the FRB and at the subbasin outlets is examined within a regression framework. The influence of large-scale climate modes of variability (the Pacific Decadal Oscillation (PDO and the El Niño–Southern Oscillation – ENSO on APF magnitude is also assessed, and placed in context with these more localized controls. The results indicate that next to SWEmax (univariate Spearman correlation with APF of ρ ^   =  0.64; 0.70 (observations; VIC simulation, the snowmelt rate (ρ ^   =  0.43 in VIC, the

Data base of reactor physics experimental results in Kyoto University critical assembly experimental facilities

International Nuclear Information System (INIS)

Ichihara, Chihiro; Fujine, Shigenori; Hayashi, Masatoshi

1986-01-01

The Kyoto University critical assembly experimental facilities belong to the Kyoto University Research Reactor Institute, and are the versatile critical assembly constructed for experimentally studying reactor physics and reactor engineering. The facilities are those for common utilization by universities in whole Japan. During more than ten years since the initial criticality in 1974, various experiments on reactor physics and reactor engineering have been carried out using many experimental facilities such as two solidmoderated cores, a light water-moderated core and a neutron generator. The kinds of the experiment carried out were diverse, and to find out the required data from them is very troublesome, accordingly it has become necessary to make a data base which can be processed by a computer with the data accumulated during the past more than ten years. The outline of the data base, the data base CAEX using personal computers, the data base supported by a large computer and so on are reported. (Kako, I.)

Facilities Performance Indicators Report, 2004-05. Facilities Core Data Survey

Science.gov (United States)

Glazner, Steve, Ed.

2006-01-01

The purpose of "Facilities Performance Indicators" is to provide a representative set of statistics about facilities in educational institutions. The second iteration of the web-based Facilities Core Data Survey was posted and available to facilities professionals at more than 3,000 institutions in the Fall of 2005. The website offered a printed…

A Dual-Based Procedure for Dynamic Facility Location

OpenAIRE

Tony J. Van Roy; Donald Erlenkotter

1982-01-01

In dynamic facility location problems, one desires to select the time-staged establishment of facilities at different locations so as to minimize the total discounted costs for meeting demands specified over time at various customer locations. We formulate a particular dynamic facility location problem as a combinatorial optimization problem. The formulation permits both the opening of new facilities and the closing of existing ones. A branch-and-bound procedure incorporating a dual ascent me...

Facilities Performance Indicators Report 2012-13: Tracking Your Facilities Vital Signs

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2014

2014-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance Indicators Report" is designed for survey…

Summary report on the development of a cement-based formula to immobilize Hanford facility waste

International Nuclear Information System (INIS)

Gilliam, T.M.; McDaniel, E.W.; Dole, L.R.; Friedman, H.A.; Loflin, J.A.; Mattus, A.J.; Morgan, I.L.; Tallent, O.K.; West, G.A.

1987-09-01

This report recommends a cement-based grout formula to immobilize Hanford Facility Waste in the Transportable Grout Facility (TGF). Supporting data confirming compliance with all TGF performance criteria are presented. 9 refs., 24 figs., 50 tabs

BNL ACCELERATOR-BASED RADIOBIOLOGY FACILITIES

International Nuclear Information System (INIS)

LOWENSTEIN, D.I.

2000-01-01

For the past several years, the Alternating Gradient Synchrotron (AGS) at Brookhaven National Laboratory (USA) has provided ions of iron, silicon and gold, at energies from 600 MeV/nucleon to 10 GeV/nucleon, for the US National Aeronautics and Space Administration (NASA) radiobiology research program. NASA has recently funded the construction of a new dedicated ion facility, the Booster Applications Facility (BAF). The Booster synchrotron will supply ion beams ranging from protons to gold, in an energy range from 40--3,000 MeV/nucleon with maximum beam intensities of 10 10 to 10 11 ions per pulse. The BAF Project is described and the future AGS and BAF operation plans are presented

Population-based geographic access to parent and satellite National Cancer Institute Cancer Center Facilities.

Science.gov (United States)

Onega, Tracy; Alford-Teaster, Jennifer; Wang, Fahui

2017-09-01

Satellite facilities of National Cancer Institute (NCI) cancer centers have expanded their regional footprints. This study characterized geographic access to parent and satellite NCI cancer center facilities nationally overall and by sociodemographics. Parent and satellite NCI cancer center facilities, which were geocoded in ArcGIS, were ascertained. Travel times from every census tract in the continental United States and Hawaii to the nearest parent and satellite facilities were calculated. Census-based population attributes were used to characterize measures of geographic access for sociodemographic groups. From the 62 NCI cancer centers providing clinical care in 2014, 76 unique parent locations and 211 satellite locations were mapped. The overall proportion of the population within 60 minutes of a facility was 22% for parent facilities and 32.7% for satellite facilities. When satellites were included for potential access, the proportion of some racial groups for which a satellite was the closest NCI cancer center facility increased notably (Native Americans, 22.6% with parent facilities and 39.7% with satellite facilities; whites, 34.8% with parent facilities and 50.3% with satellite facilities; and Asians, 40.0% with parent facilities and 54.0% with satellite facilities), with less marked increases for Hispanic and black populations. Rural populations of all categories had dramatically low proportions living within 60 minutes of an NCI cancer center facility of any type (1.0%-6.6%). Approximately 14% of the population (n = 43,033,310) lived more than 180 minutes from a parent or satellite facility, and most of these individuals were Native Americans and/or rural residents (37% of Native Americans and 41.7% of isolated rural residents). Racial/ethnic and rural populations showed markedly improved geographic access to NCI cancer center care when satellite facilities were included. Cancer 2017;123:3305-11. © 2017 American Cancer Society. © 2017 American

Developing and Evaluating Medical Humanities Problem-Based Learning Classes Facilitated by the Teaching Assistants Majored in the Liberal Arts

Science.gov (United States)

Tseng, Fen-Yu; Shieh, Jeng-Yi; Kao, Tze-Wah; Wu, Chau-Chung; Chu, Tzong-Shinn; Chen, Yen-Yuan

2016-01-01

Abstract Although medical humanities courses taught by teachers from nonmedical backgrounds are not unusual now, few studies have compared the outcome of medical humanities courses facilitated by physicians to that by teaching assistants majored in the liberal arts. The objectives of this study were to (1) analyze the satisfaction of medical students with medical humanities problem-based learning (PBL) classes facilitated by nonmedical teaching assistants (TAF) majored in the liberal arts, and those facilitated by the attending physicians (APF) and (2) examine the satisfaction of medical students with clinical medicine-related and clinical medicine-unrelated medical humanities PBL classes. A total of 123 medical students, randomly assigned to 16 groups, participated in this study. There were 16 classes in the course: 8 of them were TAF classes; and the others were APF classes. Each week, each group rotated from 1 subject of the 16 subjects of PBL to another subject. All of the 16 groups went through all the 16 subjects in the 2013 spring semester. We examined the medical students’ satisfaction with each class, based on a rating score collected after each class was completed, using a scale from 0 (the lowest satisfaction) to 100 (the highest satisfaction). We also conducted multivariate linear regression analysis to examine the association between the independent variables and the students’ satisfaction. Medical students were more satisfied with the TAF (91.35 ± 7.75) medical humanities PBL classes than APF (90.40 ± 8.42) medical humanities PBL classes (P = 0.01). Moreover, medical students were more satisfied with the clinical medicine-unrelated topics (92.00 ± 7.10) than the clinical medicine-related topics (90.36 ± 7.99) in the medical humanities PBL course (P = 0.01). This medical humanities PBL course, including nonmedical subjects and topics, and nonmedical teaching assistants from the liberal arts as class facilitators, was

Optically-based Sensor System for Critical Nuclear Facilities Post-Event Seismic Structural Assessment

Energy Technology Data Exchange (ETDEWEB)

McCallen, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Petrone, Floriana [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Buckle, Ian [Univ. of Nevada, Reno, NV (United States); Wu, Suiwen [Univ. of Nevada, Reno, NV (United States); Coates, Jason [California State Univ., Chico, CA (United States)

2017-09-30

The U.S. Department of Energy (DOE) has ownership and operational responsibility for a large enterprise of nuclear facilities that provide essential functions to DOE missions ranging from national security to discovery science and energy research. These facilities support a number of DOE programs and offices including the National Nuclear Security Administration, Office of Science, and Office of Environmental Management. With many unique and “one of a kind” functions, these facilities represent a tremendous national investment, and assuring their safety and integrity is fundamental to the success of a breadth of DOE programs. Many DOE critical facilities are located in regions with significant natural phenomenon hazards including major earthquakes and DOE has been a leader in developing standards for the seismic analysis of nuclear facilities. Attaining and sustaining excellence in nuclear facility design and management must be a core competency of the DOE. An important part of nuclear facility management is the ability to monitor facilities and rapidly assess the response and integrity of the facilities after any major upset event. Experience in the western U.S. has shown that understanding facility integrity after a major earthquake is a significant challenge which, lacking key data, can require extensive effort and significant time. In the work described in the attached report, a transformational approach to earthquake monitoring of facilities is described and demonstrated. An entirely new type of optically-based sensor that can directly and accurately measure the earthquake-induced deformations of a critical facility has been developed and tested. This report summarizes large-scale shake table testing of the sensor concept on a representative steel frame building structure, and provides quantitative data on the accuracy of the sensor measurements.

Adaptive projective filters

International Nuclear Information System (INIS)

Dikusar, N.D.

1993-01-01

The new approach to solving of the finding problem is proposed. The method is based on Discrete Projective Transformations (DPT), the List Square Fitting (LSF) and uses the information feedback in tracing for linear or quadratic track segments (TS). The fast and stable with respect to measurement errors and background points recurrent algorithm is suggested. The algorithm realizes the family of digital adaptive projective filters (APF) with known nonlinear weight functions-projective invariants. APF can be used in adequate control systems for collection, processing and compression of data, including tracking problems for the wide class of detectors. 10 refs.; 9 figs

Facility-Based treatment of under five diarrhoea in Cross River State ...

African Journals Online (AJOL)

2015-06-29

Jun 29, 2015 ... based diarrhoea treatment strategies and guidelines by health care professional at the facility level will go a long way in improving .... p-value. Oral rehydration solution alone or given with Zinc1. 28. (10.0%). 12 (13.2%).

The effect of acidulated phosphate fluoride application on dental enamel surfaces hardness

Directory of Open Access Journals (Sweden)

Edhie Arief P

2007-09-01

Full Text Available Enamel demineralization by acid is the first step of caries process. It has recently been shown that acidulated phosphate fluoride (APF can maintain the hardness of enamel surface. The aim of this study was examine the effect of APF application in the hardest of enamel surface. Fifty extracted teeth were cut at their crown, 40 teeth were taken randomly then divided into 4 groups, group 1 as the control, group 2 was treated with APF for 1 minute, group 3 for 4 minutes and group 4 for 7 minutes, then all the samples were washed with demineralized water. To see the effect of APF, all of the samples were soaked in lactic acid demineralization solution with pH 4,5 for 72 hours., the hardness of the surfaces of those samples before and after the treatment was measured by Micro Vickers Hardness Tester. The data were analyzed using One-Way ANOVA and LSD tests. In conclusion, 1.23% APF gel can reduce higher enamel demineralization.

Tetraphenylpyrimidine-Based AIEgens: Facile Preparation, Theoretical Investigation and Practical Application

Directory of Open Access Journals (Sweden)

Junkai Liu

2017-10-01

Full Text Available Aggregation-induced emission (AIE has become a hot research area and tremendous amounts of AIE-active luminogens (AIEgens have been generated. To further promote the development of AIE, new AIEgens are highly desirable. Herein, new AIEgens based on tetraphenylpyrimidine (TPPM are rationally designed according to the AIE mechanism of restriction of intramolecular motion, and facilely prepared under mild reaction conditions. The photophysical property of the generated TPPM, TPPM-4M and TPPM-4P are systematically investigated and the results show that they feature the aggregation-enhanced emission (AEE characteristics. Theoretical study shows the high-frequency bending vibrations in the central pyrimidine ring of TPPM derivatives dominate the nonradiative decay channels. Thanks to the AEE feature, their aggregates can be used to detect explosives with super-amplification quenching effects, and the sensing ability is higher than typical AIE-active tetraphenylethene. It is anticipated that TPPM derivatives could serve as a new type of widely used AIEgen based on their facile preparation and good thermo-, photo- and chemostabilities.

Interactive CD based training on NDA instruments for facility operators and international inspectors

International Nuclear Information System (INIS)

Horley, E.C.; Smith, H.A.

1996-01-01

Interactive multimedia training is rapidly becoming a popular and highly effective medium for learning. An interactive CD based training module on the Active Well Coincidence counter is being developed for on-site training at nuclear facility, including foreign facilities. The training module incorporates interactive text, graphics and video that demonstrate the operating principles, and the use and set-up of the instrument. The user is in control of the pace of learning and of the directions taken to acquire information based on personal need. By being in control, the user stays highly motivated. A mix of visuals (text and graphics), audio clips (in different languages), and video (with audio) clips also keeps the interest level high. Skill reviews and evaluations can be incorporated into the training to provide feedback to the student. In addition, general background information is provided on gamma and neutron based MC and A measurements. This material serves as a condensed MC and A encyclopedia. By supplying an interactive CD with an NDA instrument, nuclear facilities will have greater assurance operators are properly trained in the set-up and operation of the NDA-equipment

Active Power Filter DC Bus Voltage Piecewise Reaching Law Variable Structure Control

OpenAIRE

Liu, Baolian; Ding, Zujun; Zhao, Huanyu; Jin, Defei

2014-01-01

The DC bus voltage stability control is one key technology to ensure that Active Power Filter (APF) operates stably. The external disturbances such as power grid and load fluctuation and the system parameters changing may affect the stability of APF DC bus voltage and the normal operation of APF. The mathematical model of DC bus voltage is established according to power balance principle and a DC bus voltage piecewise reaching law variable structure control algorithm is proposed to solve the ...

Utilisation of health services and the poor: deconstructing wealth-based differences in facility-based delivery in the Philippines.

Science.gov (United States)

Hodge, Andrew; Firth, Sonja; Bermejo, Raoul; Zeck, Willibald; Jimenez-Soto, Eliana

2016-07-06

Despite achieving some success, wealth-related disparities in the utilisation of maternal and child health services persist in the Philippines. The aim of this study is to decompose the principal factors driving the wealth-based utilisation gap. Using national representative data from the 2013 Philippines Demographic and Health Survey, we examine the extent overall differences in the utilisation of maternal health services can be explained by observable factors. We apply nonlinear Blinder-Oaxaca-type decomposition methods to quantify the effect of differences in measurable characteristics on the wealth-based coverage gap in facility-based delivery. The mean coverage of facility-based deliveries was respectively 41.1 % and 74.6 % for poor and non-poor households. Between 67 and 69 % of the wealth-based coverage gap was explained by differences in observed characteristics. After controlling for factors characterising the socioeconomic status of the household (i.e. the mothers' and her partners' education and occupation), the birth order of the child was the major factor contributing to the disparity. Mothers' religion and the subjective distance to the health facility were also noteworthy. This study has found moderate wealth-based disparities in the utilisation of institutional delivery in the Philippines. The results confirm the importance of recent efforts made by the Philippine government to implement equitable, pro-poor focused health programs in the most deprived geographic areas of the country. The importance of addressing the social determinants of health, particularly education, as well as developing and implementing effective strategies to encourage institutional delivery for higher order births, should be prioritised.

A spallation-based irradiation test facility for fusion and future fission materials

CERN Document Server

Samec, K; Kadi, Y; Luis, R; Romanets, Y; Behzad, M; Aleksan, R; Bousson, S

2014-01-01

The EU’s FP7 TIARA program for developing accelerator-based facilities has recently demonstrated the unique capabilities of a compact and powerful spallation source for irradiating advanced nuclear materials. The spectrum and intensity of the neutron flux produced in the proposed facility fulfils the requirements of the DEMO fusion reactor for ITER, ADS reactors and also Gen III / IV reactors. Test conditions can be modulated, covering temperature from 400 to 550°C, liquid metal corrosion, cyclical or static stress up to 500 MPa and neutron/proton irradiation damage of up to 25 DPA per annum. The entire “TMIF” facility fits inside a cube 2 metres on a side, and is dimensioned for an accelerator beam power of 100 kW, thus reducing costs and offering great versatility and flexibility.

Investigation of alternating-phase focusing for superconducting linacs

International Nuclear Information System (INIS)

Sagalovsky, L.; Delayen, J.R.

1992-01-01

The paper describes a new model of alternating-phase focusing (APF) dynamics applicable to ion linacs with short independently controlled superconducting cavities. The equations of motion are derived for a cylindrically symmetric electric field represented by a traveling wave with continuous periodic phase modulation. Solutions are obtained and analyzed for both the linear and nonlinear particle motion. Problems of linear stability and overall longitudinal acceptance are solved using standard mathematical techniques for periodic systems; analytical results are obtained. It is shown that the main beam dynamical aspects of APF are adequately described by four parameters; equilibrium synchronous phase, phase modulation amplitude, length of APF period, and incremental energy gain. The model can be applied to study the feasibility of realizing APF in a low-β section of a proton linac. (author). 9 refs., 3 figs

Communication grounding facility

International Nuclear Information System (INIS)

Lee, Gye Seong

1998-06-01

It is about communication grounding facility, which is made up twelve chapters. It includes general grounding with purpose, materials thermal insulating material, construction of grounding, super strength grounding method, grounding facility with grounding way and building of insulating, switched grounding with No. 1A and LCR, grounding facility of transmission line, wireless facility grounding, grounding facility in wireless base station, grounding of power facility, grounding low-tenton interior power wire, communication facility of railroad, install of arrester in apartment and house, install of arrester on introduction and earth conductivity and measurement with introduction and grounding resistance.

A subgradient-based branch-and-bound algorithm for the capacitated facility location problem

DEFF Research Database (Denmark)

Görtz, Simon; Klose, Andreas

This paper presents a simple branch-and-bound method based on Lagrangean relaxation and subgradient optimization for solving large instances of the capacitated facility location problem (CFLP) to optimality. In order to guess a primal solution to the Lagrangean dual, we average solutions to the L......This paper presents a simple branch-and-bound method based on Lagrangean relaxation and subgradient optimization for solving large instances of the capacitated facility location problem (CFLP) to optimality. In order to guess a primal solution to the Lagrangean dual, we average solutions...... to the Lagrangean subproblem. Branching decisions are then based on this estimated (fractional) primal solution. Extensive numerical results reveal that the method is much more faster and robust than other state-of-the-art methods for solving the CFLP exactly....

Multi-walled carbon nanotubes/graphene oxide hybrid and nanohydroxyapatite composite: A novel coating to prevent dentin erosion.

Science.gov (United States)

Nahorny, Sídnei; Zanin, Hudson; Christino, Vinie Abreu; Marciano, Fernanda Roberta; Lobo, Anderson Oliveira; Soares, Luís Eduardo Silva

2017-10-01

To date is emergent the development of novel coatings to protect erosion, especially to preventive dentistry and restorative dentistry. Here, for the first time we report the effectiveness of multi-walled carbon nanotube/graphene oxide hybrid carbon-base material (MWCNTO-GO) combined with nanohydroxyapatite (nHAp) as a protective coating for dentin erosion. Fourier transform Raman spectroscopy (FT-Raman), scanning electron (SEM), and transmission electron (TEM) microscopy were used to investigated the coatings and the effect of acidulated phosphate fluoride gel (APF) treatment on bovine teeth root dentin before and after erosion. The electrochemical corrosion performance of the coating was evaluated. Raman spectra identified that: (i) the phosphate (ν 1 PO 4 3- ) content of dentin was not significantly affected by the treatments and (ii) the carbonate (ν 1 CO 3 2- ) content in dentin increased when nHAp was used. However, the nHAp/MWCNTO-GO composite exposited lower levels of organic matrix (CH bonds) after erosion compared to other treatments. Interesting, SEM micrographs identified that the nHAp/MWCNTO-GO formed layers after erosive cycling when associate with APF treatment, indicating a possible chemical bond among them. Treatments of root dentin with nHAp, MWCNTO-GO, APF_MWCNTO-GO, and APF_nHAp/MWCNTO-GO increased the carbonate content, carbonate/phosphate ratio, and organic matrix band area after erosion. The potentiodynamic polarization curves and Nyquist plot showed that nHAp, MWCNT-GO and nHAp/MWCNT-GO composites acted as protective agents against corrosion process. Clearly, the nHAp/MWCNTO-GO composite was stable after erosive cycling and a thin and acid-resistant film was formed when associated to APF treatment. Copyright © 2017 Elsevier B.V. All rights reserved.

A study of hazardous air pollutants at the Tidd PFBC Demonstration Plant

International Nuclear Information System (INIS)

1994-10-01

The US Department of Energy (DOE) Clean Coal Technology (CCD Program is a joint effort between government and industry to develop a new generation of coal utilization processes. In 1986, the Ohio Power Company, a subsidiary of American Electric Power (AEP), was awarded cofunding through the CCT program for the Tidd Pressure Fluidized Bed Combustor (PFBC) Demonstration Plant located in Brilliant, Ohio. The Tidd PFBC unit began operation in 1990 and was later selected as a test site for an advanced particle filtration (APF) system designed for hot gas particulate removal. The APF system was sponsored by the DOE Morgantown Energy Technology Center (METC) through their Hot Gas Cleanup Research and Development Program. A complementary goal of the DOE CCT and METC R ampersand D programs has always been to demonstrate the environmental acceptability of these emerging technologies. The Clean Air Act Amendments of 1990 (CAAA) have focused that commitment toward evaluating the fate of hazardous air pollutants (HAPs) associated with advanced coal-based and hot gas cleanup technologies. Radian Corporation was contacted by AEP to perform this assessment of HAPs at the Tidd PFBC demonstration plant. The objective of this study is to assess the major input, process, and emission streams at Plant Tidd for the HAPs identified in Title III of the CAAA. Four flue gas stream locations were tested: ESP inlet, ESP outlet, APF inlet, and APF outlet. Other process streams sampled were raw coal, coal paste, sorbent, bed ash, cyclone ash, individual ESP hopper ash, APF ash, and service water. Samples were analyzed for trace elements, minor and major elements, anions, volatile organic compounds, dioxin/furan compounds, ammonia, cyanide, formaldehyde, and semivolatile organic compounds. The particle size distribution in the ESP inlet and outlet gas streams and collected ash from individual ESP hoppers was also determined

Graphics-based nuclear facility modeling and management

International Nuclear Information System (INIS)

Rod, S.R.

1991-07-01

Nuclear waste management facilities are characterized by their complexity, many unprecedented features, and numerous competing design requirements. This paper describes the development of comprehensive descriptive databases and three-dimensional models of nuclear waste management facilities and applies the database/model to an example facility. The important features of the facility database/model are its abilities to (1) process large volumes of site data, plant data, and nuclear material inventory data in an efficient, integrated manner; (2) produce many different representations of the data to fulfill information needs as they arise; (3) create a complete three-dimensional solid model of the plant with all related information readily accessible; and (4) support complete, consistent inventory control and plant configuration control. While the substantive heart of the system is the database, graphic visualization of the data vastly improves the clarity of the information presented. Graphic representations are a convenient framework for the presentation of plant and inventory data, allowing all types of information to be readily located and presented in a manner that is easily understood. 2 refs., 5 figs., 1 tab

Basic Research Firing Facility

Data.gov (United States)

Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

Surrogate Plant Data Base : Volume 2. Appendix C : Facilities Planning Baseline Data

Science.gov (United States)

1983-05-01

This four volume report consists of a data base describing "surrogate" automobile and truck manufacturing plants developed as part of a methodology for evaluating capital investment requirements in new manufacturing facilities to build new fleets of ...

A spallation-based irradiation test facility for fusion and future fission materials

International Nuclear Information System (INIS)

Samec, K.; Fusco, Y.; Kadi, Y.; Luis, R.; Romanets, Y.; Behzad, M.; Aleksan, R.; Bousson, S.

2014-01-01

The EU's FP7 TIARA program for developing accelerator-based facilities has recently demonstrated the unique capabilities of a compact and powerful spallation source for irradiating advanced nuclear materials. The spectrum and intensity of the neutron flux produced in the proposed facility fulfils the requirements of the proposed DEMO fusion reactor, ADS reactors and also Gen III / IV reactors. Test conditions can be modulated, covering temperature from 400 to 550 deg. C, liquid metal corrosion, cyclical or static stress up to 500 MPa and neutron/proton irradiation damage of up to 25 DPA per annum over a volume occupying one litre. The entire 'TMIF' facility fits inside a cube 2 metres on a side, and is dimensioned for an accelerator beam power of 100 kW, thus reducing costs and offering great versatility and flexibility. (authors)

Qt based control system software for Low Energy Accelerator Facility

International Nuclear Information System (INIS)

Basu, A.; Singh, S.; Nagraju, S.B.V.; Gupta, S.; Singh, P.

2012-01-01

Qt based control system software for Low Energy Accelerating Facility (LEAF) is operational at Bhabha Atomic Research Centre (BARC), Trombay, Mumbai. LEAF is a 50 keV negative ion electrostatic accelerator based on SNICS ion source. Control system uses Nokia Trolltech's QT 4.x API for control system software. Ni 6008 USB based multifunction cards has been used for control and read back field equipments such as power supplies, pumps, valves etc. Control system architecture is designed to be client server. Qt is chosen for its excellent GUI capability and platform independent nature. Control system follows client server architecture. The paper will describe the control system. (author)

Developing and Evaluating Medical Humanities Problem-Based Learning Classes Facilitated by the Teaching Assistants Majored in the Liberal Arts: A Longitudinal Crossover Study.

Science.gov (United States)

Tseng, Fen-Yu; Shieh, Jeng-Yi; Kao, Tze-Wah; Wu, Chau-Chung; Chu, Tzong-Shinn; Chen, Yen-Yuan

2016-02-01

Although medical humanities courses taught by teachers from nonmedical backgrounds are not unusual now, few studies have compared the outcome of medical humanities courses facilitated by physicians to that by teaching assistants majored in the liberal arts. The objectives of this study were to (1) analyze the satisfaction of medical students with medical humanities problem-based learning (PBL) classes facilitated by nonmedical teaching assistants (TAF) majored in the liberal arts, and those facilitated by the attending physicians (APF) and (2) examine the satisfaction of medical students with clinical medicine-related and clinical medicine-unrelated medical humanities PBL classes.A total of 123 medical students, randomly assigned to 16 groups, participated in this study. There were 16 classes in the course: 8 of them were TAF classes; and the others were APF classes. Each week, each group rotated from 1 subject of the 16 subjects of PBL to another subject. All of the 16 groups went through all the 16 subjects in the 2013 spring semester. We examined the medical students' satisfaction with each class, based on a rating score collected after each class was completed, using a scale from 0 (the lowest satisfaction) to 100 (the highest satisfaction). We also conducted multivariate linear regression analysis to examine the association between the independent variables and the students' satisfaction.Medical students were more satisfied with the TAF (91.35 ± 7.75) medical humanities PBL classes than APF (90.40 ± 8.42) medical humanities PBL classes (P = 0.01). Moreover, medical students were more satisfied with the clinical medicine-unrelated topics (92.00 ± 7.10) than the clinical medicine-related topics (90.36 ± 7.99) in the medical humanities PBL course (P = 0.01).This medical humanities PBL course, including nonmedical subjects and topics, and nonmedical teaching assistants from the liberal arts as class facilitators, was satisfactory. This

Inhibition of enamel demineralisation using "Nd-YAG and diode laser assisted fluoride therapy".

Science.gov (United States)

Chand, B R; Kulkarni, S; Mishra, P

2016-02-01

This in vitro study was to evaluate the irradiation efficacy of the Diode laser and the Nd-YAG laser either un-assisted or assisted by acidulated phosphate fluoride (APF) treatment on enamel's acid resistance. Seventy-two enamel samples, obtained from 12 extracted human molars, were randomly assigned to 6 groups as follows: (1) Control (C); (2) Exposed to APF gel (F); (3) Diode laser (DL); (4) Irradiated with Diode laser through APF gel (DL/F); (5) Nd-YAG laser (NL) and (6) Irradiated with Nd-YAG laser through APF gel (NL/F). The specimens were individually demineralised in an acidified hydroxyethylcellulose system, and the acid resistance was evaluated by determining the calcium ion dissolution using atomic absorption spectrometry. The average concentration of the calcium ion determined in groups 1 to 6 was 901, 757, 736, 592, 497 and 416 parts per million micrograms/gram, respectively. The results showed that demineralisation in the NL/F group was significantly less than the other groups and the control group was significantly greater than the other groups (P laser irradiation, used alone or in combination with APF, in decreasing the enamel demineralisation was greater than all the other groups.

Real-time modelling and simulation of an active power filter

Energy Technology Data Exchange (ETDEWEB)

Beaulieu, S.; Ouhrouche, M. [Quebec Univ., Chicoutimi, PQ (Canada); Dufour, C.; Allaire, P.F. [Opal RT Technologies Inc., Montreal, PQ (Canada)

2007-07-01

Power electronics converters generate harmonics and cause electromagnetic compatibility problems. Active power filter (APF) technology has advanced to the point that it can compensate for harmonics in electrical networks and provide reactive power and neutral current in AC networks. This paper presented a contribution in the design of a shunt APF for harmonics compensation in real-time simulation using the RT-LAB software package running on a simple personal computer. Real-time simulations were performed to validate the effectiveness of the proposed model. Several high-tech industries have adopted this tool for rapid control prototyping and for Hardware-in-the-Loop applications. The switching signals of the APF are determined by the hysteresis band current controller. The suitable current reference signals were determined by the algorithm based on synchronous reference frame. Real-time simulation runs showed good performance in harmonics compensation, thus satisfying the requirements of IEEE Standard 519-1992. The rate of total harmonic distortion for the source current decreased from 30 to 5 per cent. 12 refs., 1 tab., 9 figs.

A Recirculating Linac-Based Facility for Ultrafast X-Ray Science

International Nuclear Information System (INIS)

Corlett, J. N.; Barletta, W. A.; DeSantis, S.; Doolittle, L.; Fawley, W. M.; Green, M.A.; Heimann, P.; Leone, S.; Lidia, S.; Li, D.; Ratti, A.; Robinson, K.; Schoenlein, R.; Staples, J.; Wan, W.; Wells, R.; Wolski, A.; Zholents, A.; Parmigiani, F.; Placidi, M.; Pirkl, W.; Rimmer, R. A.; Wang, S.

2003-01-01

We present an updated design for a proposed source of ultra-fast synchrotron radiation pulses based on a recirculating superconducting linac [1,2], in particular the incorporation of EUV and soft x-ray production. The project has been named LUX--Linac-based Ultrafast X-ray facility. The source produces intense x-ray pulses with duration of 10-100 fs at a 10 kHz repetition rate, with synchronization of 10's fs, optimized for the study of ultra-fast dynamics. The photon range covers the EUV to hard x-ray spectrum by use of seeded harmonic generation in undulators, and a specialized technique for ultra-short pulse photon production in the 1-10 keV range. High brightness rf photocathodes produce electron bunches which are optimized either for coherent emission in free electron lasers, or to provide a large x/y emittance ration and small vertical emittance which allows for manipulation to produce short-pulse hard x-rays. An injector linac accelerates the beam to 120 MeV, and is followed by f our passes through a 600-720 MeV recirculating linac. We outline the major technical components of the proposed facility

Novel and facile viscometer using a paper-based microfluidic device

Science.gov (United States)

Kang, Hyunwoong; Jang, Ilhoon; Song, Simon

2017-11-01

In clinical applications, it is important to rapidly estimate the blood viscosity of a patient with a high accuracy and a small sample consumption. Unfortunately, ordinary mechanical viscometers require long analysis time, large volume of sample and skilled person. To address this issue, silicon-based viscometers have been developed, but they are still far from prevail usage in clinical environments due to complexity in process and analysis. Recently, a paper-based microfluidic device is emerged as a new platform for a facile point-of-care diagnostic device due to low cost, disposability and ease of use. Thus, we propose a novel and facile method of measuring a viscosity with a paper-based microfluidic devices and a smartphone. This viscometer utilizes mixing characteristics of two fluid flows in a T-shape channel: one for reference and the other for test fluid. The mixing strongly depends on viscosity difference between the two fluids. Also, the fluids are dyed for colorimetric analysis with a smartphone. We found that the accuracy of viscometer is about 3 percent when it was tested for various glycerin aqueous solutions. More detailed information will be discussed in the presentation. This work was supported by the National Research Foundation of Korea(NRF) Grant funded by the Korea government(MSIP) (No. 2016R1A2B3009541).

Analysis of Hanford-based Options for Sustainable DOE Facilities on the West Coast

Energy Technology Data Exchange (ETDEWEB)

Warwick, William M.

2012-06-30

Large-scale conventional energy projects result in lower costs of energy (COE). This is true for most renewable energy projects as well. The Office of Science is interested in its facilities meeting the renewable energy mandates set by Congress and the Administration. Those facilities on the west coast include a cluster in the Bay Area of California and at Hanford in central Washington State. Land constraints at the California facilities do not permit large scale projects. The Hanford Reservation has land and solar insolation available for a large scale solar project as well as access to a regional transmission system that can provide power to facilities in California. The premise of this study is that a large-scale solar project at Hanford may be able to provide renewable energy sufficient to meet the needs of select Office of Science facilities on the west coast at a COE that is competitive with costs in California despite the lower solar insolation values at Hanford. The study concludes that although the cost of solar projects continues to decline, estimated costs for a large-scale project at Hanford are still not competitive with avoided power costs for Office of Science facilities on the west coast. Further, although it is possible to transmit power from a solar project at Hanford to California facilities, the costs of doing so add additional costs. Consequently, development of a large- scale solar project at Hanford to meet the renewable goals of Office of Science facilities on the west coast is currently uneconomic. This may change as solar costs decrease and California-based facilities face increasing costs for conventional and renewable energy produced in the state. PNNL should monitor those cost trends.

Radiation dose evaluation based on exposure scenario during the operation of radioactive waste disposal facility

International Nuclear Information System (INIS)

Yoon, Jeong Hyoun; Kim Chang Lak; Choi, Heui Joo; Park, Joo Wan

1999-01-01

Radiation dose to worker in disposal facility was calculated by using point kernel MICROSHIELD V5.02 computer code based on exposure scenarios. An conceptual design model for disposal vaults in disposal facility was used for object of shielding calculation model. Selected radionuclides and their activities among radioactive wastes from nuclear power plants were assumed as radiation sources for the exposure calculation. Annual radiation doses to crane workers and to people working on disposal vaults were calculated according to exposure time and distance from the sources with conservative operation scenarios. The scenarios used for this study were based on assumption for representing disposal activities in a future Korean near surface disposal facility. Calculated exposure rates to worker during normal disposal work were very low comparing with annual allowable limit for radiation worker

Sustainable Facilities Management

DEFF Research Database (Denmark)

Nielsen, Susanne Balslev; Elle, Morten; Hoffmann, Birgitte

2004-01-01

The Danish public housing sector has more than 20 years of experience with sustainable facilities management based on user involvement. The paper outlines this development in a historical perspective and gives an analysis of different approaches to sustainable facilities management. The focus...... is on the housing departments and strateies for the management of the use of resources. The research methods used are case studies based on interviews in addition to literature studies. The paper explores lessons to be learned about sustainable facilities management in general, and points to a need for new...

DUPIC facility engineering

Energy Technology Data Exchange (ETDEWEB)

Lee, J S; Choi, J W; Go, W I; Kim, H D; Song, K C; Jeong, I H; Park, H S; Im, C S; Lee, H M; Moon, K H; Hong, K P; Lee, K S; Suh, K S; Kim, E K; Min, D K; Lee, J C; Chun, Y B; Paik, S Y; Lee, E P; Yoo, G S; Kim, Y S; Park, J C

1997-09-01

In the early stage of the project, a comprehensive survey was conducted to identify the feasibility of using available facilities and of interface between those facilities. It was found out that the shielded cell M6 interface between those facilities. It was found out that the shielded cell M6 of IMEF could be used for the main process experiments of DUPIC fuel fabrication in regard to space adequacy, material flow, equipment layout, etc. Based on such examination, a suitable adapter system for material transfer around the M6 cell was engineered. Regarding the PIEF facility, where spent PWR fuel assemblies are stored in an annex pool, disassembly devices in the pool are retrofitted and spent fuel rod cutting and shipping system to the IMEF are designed and built. For acquisition of casks for radioactive material transport between the facilities, some adaptive refurbishment was applied to the available cask (Padirac) based on extensive analysis on safety requirements. A mockup test facility was newly acquired for remote test of DUPIC fuel fabrication process equipment prior to installation in the M6 cell of the IMEF facility. (author). 157 refs., 57 tabs., 65 figs.

DUPIC facility engineering

International Nuclear Information System (INIS)

Lee, J. S.; Choi, J. W.; Go, W. I.; Kim, H. D.; Song, K. C.; Jeong, I. H.; Park, H. S.; Im, C. S.; Lee, H. M.; Moon, K. H.; Hong, K. P.; Lee, K. S.; Suh, K. S.; Kim, E. K.; Min, D. K.; Lee, J. C.; Chun, Y. B.; Paik, S. Y.; Lee, E. P.; Yoo, G. S.; Kim, Y. S.; Park, J. C.

1997-09-01

In the early stage of the project, a comprehensive survey was conducted to identify the feasibility of using available facilities and of interface between those facilities. It was found out that the shielded cell M6 interface between those facilities. It was found out that the shielded cell M6 of IMEF could be used for the main process experiments of DUPIC fuel fabrication in regard to space adequacy, material flow, equipment layout, etc. Based on such examination, a suitable adapter system for material transfer around the M6 cell was engineered. Regarding the PIEF facility, where spent PWR fuel assemblies are stored in an annex pool, disassembly devices in the pool are retrofitted and spent fuel rod cutting and shipping system to the IMEF are designed and built. For acquisition of casks for radioactive material transport between the facilities, some adaptive refurbishment was applied to the available cask (Padirac) based on extensive analysis on safety requirements. A mockup test facility was newly acquired for remote test of DUPIC fuel fabrication process equipment prior to installation in the M6 cell of the IMEF facility. (author). 157 refs., 57 tabs., 65 figs

Facilities Performance Indicators Report 2011-12: Tracking Your Facilities Vital Signs

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2013

2013-01-01

This paper provides an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. APPA's Information and Research Committee's goal for this year was to enhance the…

Establishing the NeuroRecovery Network Community Fitness and Wellness facilities: multi-site fitness facilities provide activity-based interventions and assessments for evidence-based functional gains in neurologic disorders.

Science.gov (United States)

Tolle, Heather; Rapacz, Andrew; Weintraub, Barry; Shogren, Carrie; Harkema, Susan J; Gibson, Jeremy L

2017-08-17

Physical fitness is a necessity for those living with a spinal cord injury, yet access to fitness facilities, equipment, and specially trained fitness experts are limited. This article introduces the concept of a network of fitness facilities specially geared towards individuals with spinal cord injury and other neurological disorders. The Community Fitness and Wellness branch of the NeuroRecovery Network was created to provide a continuum of care after traditional rehabilitation for individuals living with a spinal cord injury and other neurological disorders. Community Fitness and Wellness facilities translate activity-based interventions performed during rehabilitation into a community setting as well as provide other fitness and wellness opportunities. Community Fitness and Wellness facilities are staffed by professionals with training on the specialized needs of individuals living with spinal cord injury or other neurological disorders. Standardized assessments evaluate functional, health, and quality of life gains at regular intervals. A national database gathers information on standardized interventions and assessment outcomes providing a mechanism for evaluation of interventions performed in the community setting. The establishment of Community Fitness and Wellness facilities allows for the quick translation and evaluation of novel, effective approaches from research to individuals in the community. Implications for Rehabilitation Fitness needs of individuals with spinal cord injury living in the community necessitate the use of special equipment and trained staff. Community Fitness and Wellness Programs offer specially trained staff and adaptive equipment providing a continuity of care for those with spinal cord injuries and other neurological disorders.

Facilities Performance Indicators Report, 2008-09

Science.gov (United States)

Hills, Christina, Ed.

2010-01-01

This paper features another expanded Web-based Facilities Performance Indicators Report (FPI). The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. The 2008-09 iteration of the Web-based Facilities Performance Indicators Survey was posted and…

Efficacy of various topical agents to prevent enamel demineralization

Directory of Open Access Journals (Sweden)

Priska Lestari Hendrawan

2011-09-01

Full Text Available Background: Enamel demineralization is a common and undesirable side effect of fixed appliance orthodontic treatment. Many sudies showed that the prevalence varied between 2–96%. There are many ways to prevent demineralization and increased remineralization such as oral hygiene instruction and by topical application such as acidulated phosphate fluor (APF casein phospo peptide-amorphous calcium phosphate (CPP-ACP, casein phospo peptide-amorphous calcium phosphate plus (CPP-ACPF. Purpose: The purpose of this in-vitro study was to evaluate the efficacy of various topical agents to prevent enamel demineralization. Methods: Fourty extracted human premolars were allocated to 1 of 4 groups: 1.23% APF gel; 10% CPP-ACP paste; 10% CPP-ACPF paste; and untreated control. All samples were subjected to pH cycling treatment for 12 days through a daily procedure of demineralization solution with pH 4 for 6 hours and remineralization solution with pH 7 for 18 hours. Microhardness testing were done before and after pH cycling and the delta hardness values were determined. Results: APF, CPP-ACP and CPP-ACPF application significantly prevent lowering of enamel microhardness value compared with untreated control group. Kruskal-Wallis, ANOVA, Mann-Whitney U, Tukey and Bonferroni Post-Hoc multiple comparison test showed significant difference between mean delta microhardness value of CPP-ACPF and CPP-ACP group with APF group, but there is no significant difference between mean delta microhardness value of CPP-ACPF and CPP-ACP group. Conclusion: APF, CPP-ACP and CPP-ACPF prevent enamel demineralization. CPP-ACP and CPP-ACPF prevent demineralization more than APF.Latar belakang: Demineralisasi email merupakan efek samping negatif yang sering dijumpai pada perawatan ortodontik cekat. Beberapa penelitian menyatakan bahwa prevalensinya bervariasi 2–96 persen. Ada beberapa cara untuk mencegah demineralisasi dan meningkatkan remineralisasi, misalnya dengan instruksi

Development of Accident Scenario for Interim Spent Fuel Storage Facility Based on Fukushima Accident

Energy Technology Data Exchange (ETDEWEB)

Lee, Dongjin; Choi, Kwangsoon; Yoon, Hyungjoon; Park, Jungsu [KEPCO-E and C, Yongin (Korea, Republic of)

2014-05-15

700 MTU of spent nuclear fuel is discharged from nuclear fleet every year and spent fuel storage is currently 70.9% full. The on-site wet type spent fuel storage pool of each NPP(nuclear power plants) in Korea will shortly exceed its storage limit. Backdrop, the Korean government has rolled out a plan to construct an interim spent fuel storage facility by 2024. However, the type of interim spent fuel storage facility has not been decided yet in detail. The Fukushima accident has resulted in more stringent requirements for nuclear facilities in case of beyond design basis accidents. Therefore, there has been growing demand for developing scenario on interim storage facility to prepare for beyond design basis accidents and conducting dose assessment based on the scenario to verify the safety of each type of storage.

A LAN with real-time facilities based on OSI concepts

International Nuclear Information System (INIS)

Raaf, A.J. de; Dijkstra, A.; Swierstra, S.D.

1986-01-01

Research is being done into structured design and realization methods for Local Area Networks (LAN's). The main aim is to develop a LAN (ZWOLAN) with real-time facilities for use in laboratories and based on ISO-OSI standards. Twentenet will be used for the physical and the data link layer of ZWOLAN. Twentenet is based on a Priority based CSMA/CD data link access mechanism with guaranteed access times. An implementation model has been constructed from an FSM decomposition analysis of OSI protocols. Modular Pascal will be used as language for the realization of the network software. The emphasis is on the software architecture and the reduction of the OSI protocol overhead. (Auth.)

A facile molecularly imprinted polymer-based fluorometric assay for detection of histamine

DEFF Research Database (Denmark)

Feng, Xiaotong; Ashley, Jon; Zhou, Tongchang

2018-01-01

urgently needed. In this paper, we developed a facile and cost-effective molecularly imprinted polymer (MIP)-based fluorometric assay to directly quantify histamine. Histamine-specific MIP nanoparticles (nanoMIPs) were synthesized using a modified solid-phase synthesis method. They were then immobilized...

The impact of targeted subsidies for facility-based delivery on access to care and equity - evidence from a population-based study in rural Burkina Faso.

Science.gov (United States)

De Allegri, Manuela; Ridde, Valéry; Louis, Valérie R; Sarker, Malabika; Tiendrebéogo, Justin; Yé, Maurice; Müller, Olaf; Jahn, Albrecht

2012-11-01

We conducted the first population-based impact assessment of a financing policy introduced in Burkina Faso in 2007 on women's access to delivery services. The policy offers an 80 per cent subsidy for facility-based delivery. We collected information on delivery in five repeated cross-sectional surveys carried out from 2006 to 2010 on a representative sample of 1050 households in rural Nouna Health District. Over the 5 years, the proportion of facility-based deliveries increased from 49 to 84 per cent (Ptariff of 900 CFA. Our findings indicate the operational effectiveness of the policy in increasing the use of facility-based delivery services for women. The potential to reduce maternal mortality substantially has not yet been assessed by health outcome measures of neonatal and maternal mortality.

Active Power Filter DC Bus Voltage Piecewise Reaching Law Variable Structure Control

Directory of Open Access Journals (Sweden)

Baolian Liu

2014-01-01

Full Text Available The DC bus voltage stability control is one key technology to ensure that Active Power Filter (APF operates stably. The external disturbances such as power grid and load fluctuation and the system parameters changing may affect the stability of APF DC bus voltage and the normal operation of APF. The mathematical model of DC bus voltage is established according to power balance principle and a DC bus voltage piecewise reaching law variable structure control algorithm is proposed to solve the above problem, and the design method is given. The simulation and experiment results proved that the proposed variable structure control algorithm can eliminate the chattering problem existing in traditional variable structure control effectively, is insensitive to system disturbance, and has good robustness and fast dynamic response speed and stable DC bus voltage with small fluctuation. The above advantages ensure the compensation effect of APF.

Feasibility study for a biomedical experimental facility based on LEIR at CERN

CERN Document Server

Abler, Daniel; Carli, Christian; Dosanjh, Manjit; Peach, Ken; Orecchia, Roberto

2013-01-01

In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. This basic research would support the current clinical efforts of the new treatment centres in Europe (for example HIT, CNAO and MedAustron). This paper presents first investigations on the feasibility of an experimental biomedical facility based on the CERN Low Energy Ion Ring LEIR accelerator. Such a new facility could provide beams of light ions (from protons to neon ions) in a collaborative and cost-effective way, since it would rely partly on CERN’s competences and infrastructure. The main technical challenges linked to the implementation of a slow extraction scheme for LEIR an...

Consumer Choice Between Hospital-Based and Freestanding Facilities for Arthroscopy: Impact on Prices, Spending, and Surgical Complications.

Science.gov (United States)

Robinson, James C; Brown, Timothy T; Whaley, Christopher; Bozic, Kevin J

2015-09-16

Hospital-based outpatient departments traditionally charge higher prices for ambulatory procedures, compared with freestanding surgery centers. Under emerging reference-based benefit designs, insurers establish a contribution limit that they will pay, requiring the patient to pay the difference between that contribution limit and the actual price charged by the facility. The purpose of this study was to evaluate the impact of reference-based benefits on consumer choices, facility prices, employer spending, and surgical outcomes for orthopaedic procedures performed at ambulatory surgery centers. We obtained data on 3962 patients covered by the California Public Employees' Retirement System (CalPERS) who underwent arthroscopy of the knee or shoulder in the three years prior to the implementation of reference-based benefits in January 2012 and on 2505 patients covered by CalPERS who underwent arthroscopy in the two years after implementation. Control group data were obtained on 57,791 patients who underwent arthroscopy and were not subject to reference-based benefits. The impact of reference-based benefits on consumer choices between hospital-based and freestanding facilities, facility prices, employer spending, and surgical complications was assessed with use of difference-in-differences multivariable regressions to adjust for patient demographic characteristics, comorbidities, and geographic location. By the second year of the program, the shift to reference-based benefits was associated with an increase in the utilization of freestanding ambulatory surgery centers by 14.3 percentage points (95% confidence interval, 8.1 to 20.5 percentage points) for knee arthroscopy and by 9.9 percentage points (95% confidence interval, 3.2 to 16.7 percentage points) for shoulder arthroscopy and a corresponding decrease in the use of hospital-based facilities. The mean price paid by CalPERS fell by 17.6% (95% confidence interval, -24.9% to -9.6%) for knee procedures and by 17

Performance of grid-tied PV facilities: A case study based on real data

International Nuclear Information System (INIS)

Díez-Mediavilla, M.; Dieste-Velasco, M.I.; Rodríguez-Amigo, M.C.; García-Calderón, T.; Alonso-Tristán, C.

2013-01-01

Highlights: • A new procedure to analyse the performance of PV facilities is presented. • It only requires limited amounts of data that are easily sourced. • Data sets on production were collected over two complete years. • The transformerless inverter outperforms the isolated inverter. - Abstract: A new procedure is presented to analyse the performance of grid-tied PV facilities. It needs limited amounts of data that are easily sourced and is based on knowledge of the analysed system and its mode of operation. The procedure is applied, in a case study, to compare real PV production at two 100 kW p grid-connected PV installations. Located in the same geographical region, the installation of these two facilities followed the same construction criteria – PV panels, panel support system and wiring – and the facilities were exposed to the same atmospheric temperature and solar radiation. They differ with regard to their inverter technology: one facility uses an inverter with an integrated transformer system and the other uses a transformerless inverter. The results show that the transformerless inverter system performed better than the isolated system by a factor of 1.2%, which, in economic terms, represents more than 2000 €/year

Corrosion and hydrogen absorption of commercially pure zirconium in acid fluoride solutions

International Nuclear Information System (INIS)

Yokoyama, Ken’ichi; Yamada, Daisuke; Sakai, Jun’ichi

2013-01-01

Highlights: •Zirconium corrodes and absorbs hydrogen in acid fluoride solutions. •Hydrogen thermal desorption is observed at 300–700 °C. •The resistance to hydrogen absorption of zirconium is higher than that of titanium. -- Abstract: The corrosion and hydrogen absorption of commercially pure zirconium have been investigated in acidulated phosphate fluoride (APF) solutions. Upon immersion in 2.0% APF solution of pH 5.0 at 25 °C, a granular corrosion product (Na 3 ZrF 7 ) deposits over the entire side surface of the specimen, thereby inhibiting further corrosion. In 0.2% APF solution, marked corrosion is observed from the early stage of immersion; no deposition of the corrosion product is observed by scanning electron microscopy. A substantial amount of hydrogen absorption is confirmed in both APF solutions by hydrogen thermal desorption analysis. The amount of absorbed hydrogen of the specimen immersed in the 2.0% APF solution is smaller than that in the 0.2% APF solution in the early stage of immersion. The hydrogen absorption behavior is not always consistent with the corrosion behavior. Hydrogen thermal desorption occurs in the temperature range of 300–700 °C for the specimen without the corrosion product. Under the same immersion conditions, the amount of absorbed hydrogen in commercially pure zirconium is smaller than that in commercially pure titanium as reported previously. The present results suggest that commercially pure zirconium, compared with commercially pure titanium, is highly resistant to hydrogen absorption, although corrosion occurs in fluoride solutions

Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo.

Science.gov (United States)

Yang, Wei; Kim, Yongsoo; Kim, Taek-Kyun; Keay, Susan K; Kim, Kwang Pyo; Steen, Hanno; Freeman, Michael R; Hwang, Daehee; Kim, Jayoung

2012-12-01

What's known on the subject? and What does the study add? Interstitial cystitis (IC) is a prevalent and debilitating pelvic disorder generally accompanied by chronic pain combined with chronic urinating problems. Over one million Americans are affected, especially middle-aged women. However, its aetiology or mechanism remains unclear. No efficient drug has been provided to patients. Several urinary biomarker candidates have been identified for IC; among the most promising is antiproliferative factor (APF), whose biological activity is detectable in urine specimens from >94% of patients with both ulcerative and non-ulcerative IC. The present study identified several important mediators of the effect of APF on bladder cell physiology, suggesting several candidate drug targets against IC. In an attempt to identify potential proteins and genes regulated by APF in vivo, and to possibly expand the APF-regulated network identified by stable isotope labelling by amino acids in cell culture (SILAC), we performed an integration analysis of our own SILAC data and the microarray data of Gamper et al. (2009) BMC Genomics 10: 199. Notably, two of the proteins (i.e. MAPKSP1 and GSPT1) that are down-regulated by APF are involved in the activation of mTORC1, suggesting that the mammalian target of rapamycin (mTOR) pathway is potentially a critical pathway regulated by APF in vivo. Several components of the mTOR pathway are currently being studied as potential therapeutic targets in other diseases. Our analysis suggests that this pathway might also be relevant in the design of diagnostic tools and medications targeting IC. • To enhance our understanding of the interstitial cystitis urine biomarker antiproliferative factor (APF), as well as interstitial cystitis biology more generally at the systems level, we reanalyzed recently published large-scale quantitative proteomics and in vivo transcriptomics data sets using an integration analysis tool that we have developed. • To

Meeting the challenges of bringing a new base facility operation model to Gemini Observatory

Science.gov (United States)

Nitta, Atsuko; Arriagada, Gustavo; Adamson, A. J.; Cordova, Martin; Nunez, Arturo; Serio, Andrew; Kleinman, Scot

2016-08-01

The aim of the Gemini Observatory's Base Facilities Project is to provide the capabilities to perform routine night time operations with both telescopes and their instruments from their respective base facilities without anyone present at the summit. Tightening budget constraints prompted this project as both a means to save money and an opportunity to move toward increasing remote operations in the future. We successfully moved Gemini North nighttime operation to our base facility in Hawaii in Nov., 2015. This is the first 8mclass telescope to completely move night time operations to base facility. We are currently working on implementing BFO to Gemini South. Key challenges for this project include: (1) This is a schedule driven project. We have to implement the new capabilities by the end of 2015 for Gemini North and end of 2016 for Gemini South. (2) The resources are limited and shared with operations which has the higher priority than our project. (3) Managing parallel work within the project. (4) Testing, commissioning and introducing new tools to operational systems without adding significant disruptions to nightly operations. (5) Staff buying to the new operational model. (6) The staff involved in the project are spread on two locations separated by 10,000km, seven time zones away from each other. To overcome these challenges, we applied two principles: "Bare Minimum" and "Gradual Descent". As a result, we successfully completed the project ahead of schedule at Gemini North Telescope. I will discuss how we managed the cultural and human aspects of the project through these concepts. The other management aspects will be presented by Gustavo Arriagada [2], the Project Manager of this project. For technical details, please see presentations from Andrew Serio [3] and Martin Cordova [4].

Microfilms packaging and coating: effects on shelf life and quality of ...

African Journals Online (AJOL)

Studies on storage potential of African pear fruits (APFs) were conducted using three packaging microfilms (low density polyethylene, low density polypropylene and highdensity polypropylene) and three coating materials (sheanut butter, palm oil and paraffin wax). The packaged and coated APFs were separately stored at ...

Developing Mobile- and BIM-Based Integrated Visual Facility Maintenance Management System

Directory of Open Access Journals (Sweden)

Yu-Cheng Lin

2013-01-01

Full Text Available Facility maintenance management (FMM has become an important topic for research on the operation phase of the construction life cycle. Managing FMM effectively is extremely difficult owing to various factors and environments. One of the difficulties is the performance of 2D graphics when depicting maintenance service. Building information modeling (BIM uses precise geometry and relevant data to support the maintenance service of facilities depicted in 3D object-oriented CAD. This paper proposes a new and practical methodology with application to FMM using BIM technology. Using BIM technology, this study proposes a BIM-based facility maintenance management (BIMFMM system for maintenance staff in the operation and maintenance phase. The BIMFMM system is then applied in selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FMM practice. Using the BIMFMM system, maintenance staff can access and review 3D BIM models for updating related maintenance records in a digital format. Moreover, this study presents a generic system architecture and its implementation. The combined results demonstrate that a BIMFMM-like system can be an effective visual FMM tool.

Electron energy device for LINAC based Pulse Radiolysis Facility of RPCD

International Nuclear Information System (INIS)

Toley, M.A.; Shinde, S.J.; Chaudhari, B.B.; Sarkar, S.K.

2015-07-01

The pulse radiolysis facility is the experimental centerpiece of the radiation chemistry activities of the Radiation and Photochemistry Division (RPCD) of Bhabha Atomic Research Centre. This facility was created in 1986 which is based on a 7 MeV Linear Electron Accelerator (LINAC) procured from M/s Radiation Dynamics Ltd., UK. The electron energy is one of the principal parameters that influence the dose distribution within the sample irradiated with a beam of energetic electrons. An easy-to-use and robust device has been developed that can reliably detect day-today small variations in the beam energy. It consists of two identical aluminum plates except for their thickness, which are electrically insulated from each other. The thickness of each plate is carefully selected depending on the electron beam energy. The charge (or current) collected by each plate, under irradiation is measured. The ratio of the charge (or current) signal from the front plate to the sum of the signals from the front and rear plates is very sensitive to the beam energy. The high sensitivity and robustness make this device quite suitable for Electron energy measurement for Pulse radiolysis Facility at RPCD. (author)

7-MeV electron LINAC based pulse radiolysis facility at RPCD, BARC

International Nuclear Information System (INIS)

Naik, C.B.; Nadkarni, S.A.; Toley, M.A.; Shinde, S.J.; Naik, P.D.

2017-01-01

7-MeV electron LINAC based pulse radiolysis facility is operational in Chemistry Group of BARC since 1986. The Accelerator is housed in B-132 room in basement of Modular Labs. BARC Accelerator was procured from Radiation Dynamics Inc. UK and its detection system was indigenously developed

Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey.

Directory of Open Access Journals (Sweden)

John Ly

2016-08-01

Full Text Available The Ebola virus disease (EVD epidemic has threatened access to basic health services through facility closures, resource diversion, and decreased demand due to community fear and distrust. While modeling studies have attempted to estimate the impact of these disruptions, no studies have yet utilized population-based survey data.We conducted a two-stage, cluster-sample household survey in Rivercess County, Liberia, in March-April 2015, which included a maternal and reproductive health module. We constructed a retrospective cohort of births beginning 4 y before the first day of survey administration (beginning March 24, 2011. We then fit logistic regression models to estimate associations between our primary outcome, facility-based delivery (FBD, and time period, defined as the pre-EVD period (March 24, 2011-June 14, 2014 or EVD period (June 15, 2014-April 13, 2015. We fit both univariable and multivariable models, adjusted for known predictors of facility delivery, accounting for clustering using linearized standard errors. To strengthen causal inference, we also conducted stratified analyses to assess changes in FBD by whether respondents believed that health facility attendance was an EVD risk factor. A total of 1,298 women from 941 households completed the survey. Median age at the time of survey was 29 y, and over 80% had a primary education or less. There were 686 births reported in the pre-EVD period and 212 in the EVD period. The unadjusted odds ratio of facility-based delivery in the EVD period was 0.66 (95% confidence interval [CI] 0.48-0.90, p-value = 0.010. Adjustment for potential confounders did not change the observed association, either in the principal model (adjusted odds ratio [AOR] = 0.70, 95%CI 0.50-0.98, p = 0.037 or a fully adjusted model (AOR = 0.69, 95%CI 0.50-0.97, p = 0.033. The association was robust in sensitivity analyses. The reduction in FBD during the EVD period was observed among those reporting a belief that

The preliminary Long Duration Exposure Facility (LDEF) materials data base

International Nuclear Information System (INIS)

Funk, J.G.; Strickland, J.W.; Davis, J.M.

1992-10-01

A preliminary Long Duration Exposure Facility (LDEF) Materials Data Base was developed by the LDEF Materials Special Investigation Group (MSIG). The LDEF Materials Data Base is envisioned to eventually contain the wide variety and vast quantity of materials data generated for LDEF. The data is searchable by optical, thermal, and mechanical properties, exposure parameters (such as atomic oxygen flux), and author(s) or principal investigator(s). The LDEF Materials Data Base was incorporated into the Materials and Processes Technical Information System (MAPTIS). MAPTIS is a collection of materials data which was computerized and is available to engineers, designers, and researchers in the aerospace community involved in the design and development of spacecraft and related hardware. This paper describes the LDEF Materials Data Base and includes step-by-step example searches using the data base. Information on how to become an authorized user of the system is included

The preliminary Long Duration Exposure Facility (LDEF) materials data base

Science.gov (United States)

Funk, Joan G.; Strickland, John W.; Davis, John M.

1992-01-01

A preliminary Long Duration Exposure Facility (LDEF) Materials Data Base was developed by the LDEF Materials Special Investigation Group (MSIG). The LDEF Materials Data Base is envisioned to eventually contain the wide variety and vast quantity of materials data generated for LDEF. The data is searchable by optical, thermal, and mechanical properties, exposure parameters (such as atomic oxygen flux), and author(s) or principal investigator(s). The LDEF Materials Data Base was incorporated into the Materials and Processes Technical Information System (MAPTIS). MAPTIS is a collection of materials data which was computerized and is available to engineers, designers, and researchers in the aerospace community involved in the design and development of spacecraft and related hardware. This paper describes the LDEF Materials Data Base and includes step-by-step example searches using the data base. Information on how to become an authorized user of the system is included.

Harnessing the Power of Light to See and Treat Breast Cancer

Science.gov (United States)

2015-12-01

APFs roughly correspond to nuclei, in some cases nucleic acids are concentrated within the nucleoli of neoplastic cells; therefore, we refer to these...likely to correspond to nucleoli , while APFs larger than the threshold are likely to correspond to nuclei [49]. Specifically, others have found that...

Wind forced variability of the Antarctic circumpolar current south of Africa between 1993 and 2010

CSIR Research Space (South Africa)

Domingues, R

2014-02-01

Full Text Available positive SAM is linked to reduced (increased) SAF (APF) transports and a warmer mixed layer in the ACC. The link between the changes in the wind stress and the SAF and APF transport variations occurs through the development of Ekman pumping anomalies near...

Responses of seabirds, in particular prions (Pachyptila sp.), to small-scale processes in the Antarctic Polar Front

NARCIS (Netherlands)

Franeker, van J.A.; Brink, van den N.W.; Bathmann, U.V.; Pollard, R.T.; Baar, de H.J.W.; Wolff, W.J.

2002-01-01

Small-scale distribution patterns of seabirds in the Antarctic Polar Front (APF) were investigated in relation to other biological, physical, and chemical features during the ANT-XIII/2 research cruise of R.V. Polarstern from December 1995 to January 1996. The APF is characterized by steep gradients

Facility Description 2012. Summary report of the encapsulation plant and disposal facility designs

International Nuclear Information System (INIS)

Palomaeki, J.; Ristimaeki, L.

2013-10-01

The purpose of the facility description is to be a specific summary report of the scope of Posiva's nuclear facilities (encapsulation plant and disposal facility) in Olkiluoto. This facility description is based on the 2012 designs and completing Posiva working reports. The facility description depicts the nuclear facilities and their operation as the disposal of spent nuclear fuel starts in Olkiluoto in about 2020. According to the decisions-in-principle of the government, the spent nuclear fuel from Loviisa and Olkiluoto nuclear power plants in operation and in future cumulative spent nuclear fuel from Loviisa 1 and 2, Olkiluoto 1, 2, 3 and 4 nuclear power plants, is permitted to be disposed of in Olkiluoto bedrock. The design of the disposal facility is based on the KBS-3V concept (vertical disposal). Long-term safety concept is based on the multi-barrier principle i.e. several release barriers, which ensure one another so that insufficiency in the performance of one barrier doesn't jeopardize long-term safety of the disposal. The release barriers are the following: canister, bentonite buffer and deposition tunnel backfill, and the host rock around the repository. The canisters are installed into the deposition holes, which are bored to the floor of the deposition tunnels. The canisters are enveloped with compacted bentonite blocks, which swell after absorbing water. The surrounding bedrock and the central and access tunnel backfill provide additional retardation, retention, and dilution. The nuclear facilities consist of an encapsulation plant and of underground final disposal facility including other aboveground buildings and surface structures serving the facility. The access tunnel and ventilation shafts to the underground disposal facility and some auxiliary rooms are constructed as a part of ONKALO underground rock characterization facility during years 2004-2014. The construction works needed for the repository start after obtaining the construction

[The development of the system of medical rehabilitation based at the Russian health resort facilities: investment prospects].

Science.gov (United States)

Povazhnaya, E L; Gusakova, E V; Moiseenko, S V

2018-05-21

The present work is devoted to the prospects for attracting investments for the maintenance and development of the medical rehabilitation practices based at the Russian health resort facilities. The article describes the prerequisites for the enhancement of the investment attractiveness of the development of the system of medical rehabilitation in the said institutions including the formulation and strengthening of the legal and regulatory framework, the capacity for the organization of the second and third stages of medical rehabilitation in the existing spa and health resort facilities, the attraction of the funds of compulsory medical insurance as an additional source of the financial support. The main legal documents regulating the organization and provision of medical rehabilitation based at the spa and health resort facilities are presented. The results of the implementation of the investment concept of the development of medical rehabilitation in the framework of the system of health resort treatment as exemplified by the experience of JSC «The group of companies «Medsi» are discussed. It is shown that the development of medical rehabilitation based at the spa and health resort facilities greatly contributes to the significant expansion of the potential customer base and promotes the further growth of business scale.

performance-based approach to design and evaluation of nuclear security systems for Brazilian nuclear facilities

Energy Technology Data Exchange (ETDEWEB)

Tavares, Renato L. A.; Filho, Josélio S. M., E-mail: renato.tavares@cnen.gov.br, E-mail: joselio@cnen.gov.br [Comissão Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil). Diretoria de Radioproteção e Segurança Nuclear. Divisão de Normas e Segurança Física; Fontes, Gladson S.; Fiel, J.C.B., E-mail: gsfontes@hotmail.com, E-mail: fiel@ime.eb.br [Instituto Militar de Engenharia (SE-7/IME), Rio de Janeiro, RJ (Brazil). Seção de Engenharia Nuclear

2017-07-01

This study presents an application of a performance-based approach to definition of requirements, design and evaluation of physical protection systems for nuclear facilities. Such approach considers a probabilistic analysis of the threat, equipment, systems and response forces used to prevent, dissuade and detain malicious acts against the integrity of facilities and the nuclear materials inside them. Nowadays, in the context of Brazilian nuclear facilities licensing, a mostly prescriptive approach is adopted, which despite having advantages such as simplified inspections and homogeneous regulatory requisites amid different fuel cycle facility types, does not consider evolution, dynamism and capacities of external or internal threats to facilities and to Brazilian Nuclear Program itself, neither provides metrics to evaluate system performance facing such threats. In order to preserve actual plans and systems confidentiality, a facility hypothetical model is created, including a research reactor and a waste storage facility. It is expected that the methodology and results obtained in this study serve in the future as a basis to Brazilian nuclear operators, in elaboration process of their Physical Protection Plans, which must comply with future regulation CNEN-NN 2.01, a revision of CNEN-NE 2.01, once that regulation will include performance requisites. (author)

performance-based approach to design and evaluation of nuclear security systems for Brazilian nuclear facilities

International Nuclear Information System (INIS)

Tavares, Renato L. A.; Filho, Josélio S. M.; Fontes, Gladson S.; Fiel, J.C.B.

2017-01-01

This study presents an application of a performance-based approach to definition of requirements, design and evaluation of physical protection systems for nuclear facilities. Such approach considers a probabilistic analysis of the threat, equipment, systems and response forces used to prevent, dissuade and detain malicious acts against the integrity of facilities and the nuclear materials inside them. Nowadays, in the context of Brazilian nuclear facilities licensing, a mostly prescriptive approach is adopted, which despite having advantages such as simplified inspections and homogeneous regulatory requisites amid different fuel cycle facility types, does not consider evolution, dynamism and capacities of external or internal threats to facilities and to Brazilian Nuclear Program itself, neither provides metrics to evaluate system performance facing such threats. In order to preserve actual plans and systems confidentiality, a facility hypothetical model is created, including a research reactor and a waste storage facility. It is expected that the methodology and results obtained in this study serve in the future as a basis to Brazilian nuclear operators, in elaboration process of their Physical Protection Plans, which must comply with future regulation CNEN-NN 2.01, a revision of CNEN-NE 2.01, once that regulation will include performance requisites. (author)

Gold Medal Award for Life Achievement in Psychology in the Public Interest: Beatrice A. Wright.

Science.gov (United States)

2016-01-01

The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and enduring records of accomplishment in 4 areas of psychology. The 2016 recipient of Gold Medal Award for Life Achievement in Psychology in the Public Interest is Beatrice A. Wright. Dorothy W. Cantor, president of the APF, will present the APF Gold Medal Awards at the 124th Annual Convention of the American Psychological Association on August 5, 2016, at 4:00 p.m. Members of the 2016 APF Board of Trustees are: Dorothy W. Cantor, president; David H. Barlow, vice president; Melba J. T. Vasquez, secretary; Richard C. McCarty, treasurer; Elisabeth R. Straus, executive vice president/executive director; Cynthia Belar; Camilla Benbow; Rosie Phillips Bingham; Connie S. Chan; Anthony Jackson; Terence M. Keane; Archie L. Turner; W. Bruce Walsh; and Bonnie Markham and Rick McGraw, APA Board of Directors liaisons. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Age-related incidence of pulmonary embolism and additional pathologic findings detected by computed tomography pulmonary angiography

Energy Technology Data Exchange (ETDEWEB)

Groth, M., E-mail: groth.michael@googlemail.com [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Henes, F.O., E-mail: f.henes@uke.uni-hamburg.de [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Mayer, U., E-mail: mayer@uke.uni-hamburg.de [Emergency Department, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Regier, M., E-mail: m.regier@uke.uni-hamburg.de [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Adam, G., E-mail: g.adam@uke.uni-hamburg.de [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany); Begemann, P.G.C., E-mail: p.begemann@me.com [Center for Radiology and Endoscopy, Department of Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg (Germany)

2012-08-15

Objective: To compare the incidence of pulmonary embolism (PE) and additional pathologic findings (APF) detected by computed tomography pulmonary angiography (CTPA) according to different age-groups. Materials and methods: 1353 consecutive CTPA cases for suspected PE were retrospectively reviewed. Patients were divided into seven age groups: {<=}29, 30-39, 40-49, 50-59, 60-69, 70-79 and {>=}80 years. Differences between the groups were tested using Fisher's exact or chi-square test. A p-value < 0.0024 indicated statistical significance when Bonferroni correction was used. Results: Incidence rates of PE ranged from 11.4% to 25.4% in different age groups. The three main APF were pleural effusion, pneumonia and pulmonary nodules. No significant difference was found between the incidences of PE in different age groups. Furthermore, APF in different age groups revealed no significant differences (all p-values > 0.0024). Conclusion: The incidences of PE and APF detected by CTPA reveal no significant differences between various age groups.

A novel method for designing and optimizing the layout of facilities in bathroom for the elderly in home-based rehabilitation.

Science.gov (United States)

Wang, Duojin; Wu, Jing; Lin, Qinglian

2018-05-01

The home-based rehabilitation of elderly patients improves their autonomy, independence and reintegration into society. Hence, a suitable environment plays an important role in rehabilitation, as do different assistance technologies. The majority of accidents at home involving elderly people occur in the bathroom. Therefore, the planning of the layout of facilities is important in this potentially dangerous area. This paper proposes an approach towards designing and optimizing the layout of facilities in the bathroom, based on logistical and nonlogistical relationships. A fuzzy-based analytical hierarchical process (fuzzy-AHP) is then proposed for a comprehensive evaluation of the alternatives for this layout plan. This approach was applied to the home of a 71 years old female patient, who was experiencing home-based rehabilitation. After the initial designing and optimizing of the layout of the facilities in her bathroom, a plan could then be created for her particular needs. The results of this research could then enable the home-based rehabilitation of elderly patients to be more effective. Value: This paper develops a new approach to design and optimize the layout of facilities in bathroom for the elderly. Implications for Rehabilitation Develop a new approach to design and optimize the layout of facilities in bathroom. Provide a mathematical and more scientific approach to home layout design for home-based rehabilitation. Provide new opportunities for research, for both the therapist and the patient to analyse the home facility layout.

Access to facility delivery and caesarean section in north-central Liberia: a cross-sectional community-based study

Science.gov (United States)

Gartland, Matthew G; Taryor, Victor D; Norman, Andy M; Vermund, Sten H

2012-01-01

Objective Rural north-central Liberia has one of the world's highest maternal mortality ratios. We studied health facility birthing service utilisation and the motives of women seeking or not seeking facility-based care in north-central Liberia. Design Cross-sectional community-based structured interviews and health facility medical record review. Setting A regional hospital and the surrounding communities in rural north-central Liberia. Participants A convenience sample of 307 women between 15 and 49 years participated in structured interviews. 1031 deliveries performed in the regional hospital were included in the record review. Primary outcomes Delivery within a health facility and caesarean delivery rates were used as indicators of direct utilisation of care and as markers of availability of maternal health services. Results Of 280 interview respondents with a prior childbirth, only 47 (16.8%) delivered their last child in a health facility. Women who did not use formal services cited cost, sudden labour and family tradition or religion as their principal reasons for home delivery. At the regional hospital, the caesarean delivery rate was 35.5%. Conclusions There is an enormous unmet need for maternal health services in north-central Liberia. Greater outreach and referral services as well as community-based education among women, family members and traditional midwives are vital to improve the timely utilisation of care. PMID:23117566

Technical bases for establishing a salt test facility

International Nuclear Information System (INIS)

1985-05-01

The need for a testing facility in which radioactive materials may be used in an underground salt environment is explored. No such facility is currently available in salt deposits in the United States. A salt test facility (STF) would demonstrate the feasibility of safely storing radioactive waste in salt and would provide data needed to support the design, construction, licensing, and operation of a radioactive waste repository in salt. Nineteen issues that could affect long-term isolation of waste materials in a salt repository are identified from the most pertinent recent literature. The issues are assigned an overall priority and a priority relative to the activities of the STF. Individual tests recommended for performance in the STF to resolve the 19 issues are described and organized under three groups: waste package performance, repository design and operation, and site characterization and evaluation. The requirements for a salt test facility are given in the form of functional criteria, and the approach that will be used in the design, execution, interpretation, and reporting of tests is discussed

Assessment of Maternal Satisfaction with Facility-based Childbirth ...

African Journals Online (AJOL)

AJRH Managing Editor

In Senegal, only 60% of mothers in rural areas deliver in health facilities. ... experience is one of the factors in their choosing to deliver in such facilities in ... maternal satisfaction with childbirth care and 23 standard care survey items was assessed. .... cost*. 0.64. Cheap. 30 (11.6). Affordable. 140 (54.1). Expensive. 68 (26.3).

Assessment of activity-based pyroprocess costs for an engineering-scale facility in Korea

Energy Technology Data Exchange (ETDEWEB)

Kim, Sung Ki; Ko, Won Il [Nuclear Fuel Cycle Analysis Department, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Bang, Sung Sig [Dept. of Business and Technology Management, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

2015-12-15

This study set the pyroprocess facility at an engineering scale as a cost object, and presented the cost consumed during the unit processes of the pyroprocess. For the cost calculation, the activity based costing (ABC) method was used instead of the engineering cost estimation method, which calculates the cost based on the conceptual design of the pyroprocess facility. The calculation results demonstrate that the pyroprocess facility's unit process cost is $194/kgHM for pretreatment, $298/kgHM for electrochemical reduction, $226/kgHM for electrorefining, and $299/kgHM for electrowinning. An analysis demonstrated that the share of each unit process cost among the total pyroprocess cost is as follows: 19% for pretreatment, 29% for electrochemical reduction, 22% for electrorefining, and 30% for electrowinning. The total unit cost of the pyroprocess was calculated at $1,017/kgHM. In the end, electrochemical reduction and the electrowinning process took up most of the cost, and the individual costs for these two processes was found to be similar. This is because significant raw material cost is required for the electrochemical reduction process, which uses platinum as an anode electrode. In addition, significant raw material costs are required, such as for Li3PO4, which is used a lot during the salt purification process.

Construction method for plant facility

International Nuclear Information System (INIS)

Ito, Arata; Hirono, Hideharu; Kyoda, Shigeru; Hanawa, Minoru; Sato, Hitoshi

1998-01-01

A caisson structure is disposed on a construction site for facilities of nuclear power plants. A digging work is performed below the caisson structure and, simultaneous with the digging work, a construction of a base, construction of plant facilities including a building and installation of plant facility are performed on the caisson structure. Then, the caisson structure is sank together with the structures on a base rock in association with the progress of the digging work and secured on the base rock. When securing them on the base rock, a groove is formed to the base rock along tuyere of the caisson structure so that the tuyere and a ceiling portion of the caisson structure are in direct contact with the base rock. Since the construction for the containing building conducted on the caisson structure is performed simultaneous with the digging work conducted below the caisson structure, the term required for the construction of the plant facilities can greatly reduced. (N.H.)

Conceptual design of a fission-based integrated test facility for fusion reactor components

International Nuclear Information System (INIS)

Watts, K.D.; Deis, G.A.; Hsu, P.Y.S.; Longhurst, G.R.; Masson, L.S.; Miller, L.G.

1982-01-01

The testing of fusion materials and components in fission reactors will become increasingly important because of lack of fusion engineering test devices in the immediate future and the increasing long-term demand for fusion testing when a fusion reactor test station becomes available. This paper presents the conceptual design of a fission-based Integrated Test Facility (ITF) developed by EG and G Idaho. This facility can accommodate entire first wall/blanket (FW/B) test modules such as those proposed for INTOR and can also accommodate smaller cylindrical modules similar to those designed by Oak Ridge National laboratory (ORNL) and Westinghouse. In addition, the facility can be used to test bulk breeder blanket materials, materials for tritium permeation, and components for performance in a nuclear environment. The ITF provides a cyclic neutron/gamma flux as well as the numerous module and experiment support functions required for truly integrated tests

Microscope-Based Fluid Physics Experiments in the Fluids and Combustion Facility on ISS

Science.gov (United States)

Doherty, Michael P.; Motil, Susan M.; Snead, John H.; Malarik, Diane C.

2000-01-01

At the NASA Glenn Research Center, the Microgravity Science Program is planning to conduct a large number of experiments on the International Space Station in both the Fluid Physics and Combustion Science disciplines, and is developing flight experiment hardware for use within the International Space Station's Fluids and Combustion Facility. Four fluids physics experiments that require an optical microscope will be sequentially conducted within a subrack payload to the Fluids Integrated Rack of the Fluids and Combustion Facility called the Light Microscopy Module, which will provide the containment, changeout, and diagnostic capabilities to perform the experiments. The Light Microscopy Module is planned as a fully remotely controllable on-orbit microscope facility, allowing flexible scheduling and control of experiments within International Space Station resources. This paper will focus on the four microscope-based experiments, specifically, their objectives and the sample cell and instrument hardware to accommodate their requirements.

Shunt hybrid active power filter for harmonic mitigation: A practical ...

Indian Academy of Sciences (India)

2016-08-26

Aug 26, 2016 ... The increasing importance of Power Quality problems has been responsible for several improvements in Active Power Filter (APF) typologies in the last decade. The increased cost and switching losses make a pure shunt APF economically impractical for high power applications. In higher power levels ...

Shunt hybrid active power filter for harmonic mitigation: A practical ...

Indian Academy of Sciences (India)

The increasing importance of Power Quality problems has been responsible for several improvements in Active Power Filter (APF) typologies in the last decade. The increased cost and switching losses make a pure shunt APF economically impractical for high power applications. In higher power levels shunt Hybrid Active ...

A standards-based approach to quality improvement for HIV services at Zambia Defence Force facilities: results and lessons learned.

Science.gov (United States)

Kols, Adrienne; Kim, Young-Mi; Bazant, Eva; Necochea, Edgar; Banda, Joseph; Stender, Stacie

2015-07-01

The Zambia Defence Force adopted the Standards-Based Management and Recognition approach to improve the quality of the HIV-related services at its health facilities. This quality improvement intervention relies on comprehensive, detailed assessment tools to communicate and verify adherence to national standards of care, and to test and implement changes to improve performance. A quasi-experimental evaluation of the intervention was conducted at eight Zambia Defence Force primary health facilities (four facilities implemented the intervention and four did not). Data from three previous analyses are combined to assess the effect of Standards-Based Management and Recognition on three domains: facility readiness to provide services; observed provider performance during antiretroviral therapy (ART) and antenatal care consultations; and provider perceptions of the work environment. Facility readiness scores for ART improved on four of the eight standards at intervention sites, and one standard at comparison sites. Facility readiness scores for prevention of mother-to-child transmission (PMTCT) of HIV increased by 15 percentage points at intervention sites and 7 percentage points at comparison sites. Provider performance improved significantly at intervention sites for both ART services (from 58 to 84%; P improved at intervention sites and declined at comparison sites; differences in trends between study groups were significant for eight items. A standards-based approach to quality improvement proved effective in supporting healthcare managers and providers to deliver ART and PMTCT services in accordance with evidence-based standards in a health system suffering from staff shortages.

Prevalence of pregnancy-related complications and course of labour of surviving women who gave birth in selected health facilities in Rwanda: a health facility-based, cross-sectional study.

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Semasaka Sengoma, Jean Paul; Krantz, Gunilla; Nzayirambaho, Manasse; Munyanshongore, Cyprien; Edvardsson, Kristina; Mogren, Ingrid

2017-07-09

This study estimated health facility-based prevalence for pre-eclampsia/eclampsia, postpartum haemorrhage and caesarean section (CS) due to prolonged labour/dystocia. The background characteristics of Rwandan pregnant women, the course of labour and the level of healthcare were investigated in relation to pregnancy and delivery outcomes. This is health facility-based study and data were collected in 2014-2015 through structured interviews and medical records (n=817) in Kigali and Northern Province, Rwanda. Frequencies and prevalence were used to describe participants' background factors, labour and delivery-related characteristics. Bivariable and multivariable logistic regression models were performed for different background factors and pregnancy/delivery outcomes. Pre-eclampsia/eclampsia, postpartum haemorrhage and CS due to prolonged labour/dystocia represented 1%, 2.7% and 5.4% of all participants, respectively. In total, 56.4% of the participants were transferred from facilities with low levels to those with higher levels of healthcare, and the majority were transferred from health centres to district hospitals, with CS as the main reason for transfer. Participants who arrived at the health facility with cervical dilation grade of ≤3 cm spent more hours in maternity ward than those who arrived with cervical dilatation grade of ≥4 cm. Risk factors for CS due to prolonged labour or dystocia were poor households, nulliparity and residence far from health facility. The estimated health facility-based prevalence of pregnancy-related complications was relatively low in this sample from Rwanda. CS was the main reason for the transfer of pregnant women from health centres to district hospitals. Upgrading the capacity of health centres in the management of pregnant women in Rwanda may improve maternal and fetal health. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is

Life-Cycle Assessments of Selected NASA Ground-Based Test Facilities

Science.gov (United States)

Sydnor, George Honeycutt

2012-01-01

In the past two years, two separate facility-specific life cycle assessments (LCAs) have been performed as summer student projects. The first project focused on 13 facilities managed by NASA s Aeronautics Test Program (ATP), an organization responsible for large, high-energy ground test facilities that accomplish the nation s most advanced aerospace research. A facility inventory was created for each facility, and the operational-phase carbon footprint and environmental impact were calculated. The largest impacts stemmed from electricity and natural gas used directly at the facility and to generate support processes such as compressed air and steam. However, in specialized facilities that use unique inputs like R-134a, R-14, jet fuels, or nitrogen gas, these sometimes had a considerable effect on the facility s overall environmental impact. The second LCA project was conducted on the NASA Ames Arc Jet Complex and also involved creating a facility inventory and calculating the carbon footprint and environmental impact. In addition, operational alternatives were analyzed for their effectiveness at reducing impact. Overall, the Arc Jet Complex impact is dominated by the natural-gas fired boiler producing steam on-site, but alternatives were provided that could reduce the impact of the boiler operation, some of which are already being implemented. The data and results provided by these LCA projects are beneficial to both the individual facilities and NASA as a whole; the results have already been used in a proposal to reduce carbon footprint at Ames Research Center. To help future life cycle projects, several lessons learned have been recommended as simple and effective infrastructure improvements to NASA, including better utility metering and data recording and standardization of modeling choices and methods. These studies also increased sensitivity to and appreciation for quantifying the impact of NASA s activities.

A method for studying the development pattern of urban commercial service facilities based on customer reviews from social media

Science.gov (United States)

Wang, Y. D.; Jiang, B. T.; Ye, X. Y.

2016-06-01

Urbanization is one of the most important human social activities in the 21st century (Chaolin et al., 2012). With an increasing number of people visiting cities, the provision of adequate urban service facilities, including public and commercial service facilities, in locations where people live has become an important guarantee of the success of urbanization. Exploring the commercial service facilities in a specific area of a city can help us understand the progress and trends of urban renewal in the area, provide a quantitative basis for evaluating the rationality of planning implementation, and facilitate an analysis of the effects of different factors on the regional development of a city (Schor et al. 2003). In this paper, we proposed a data processing and analysis method for studying the distribution and development pattern of urban commercial facilities based on customer reviews. In addition, based on road network constraints, we explored the patterns contained in customer reviews data, including patterns for the spatial distribution and spatial-temporal evolution of facilities as well as the number of facilities and degree of satisfaction.

A method for studying the development pattern of urban commercial service facilities based on customer reviews from social media

Directory of Open Access Journals (Sweden)

Y. D. Wang

2016-06-01

Full Text Available Urbanization is one of the most important human social activities in the 21st century (Chaolin et al., 2012. With an increasing number of people visiting cities, the provision of adequate urban service facilities, including public and commercial service facilities, in locations where people live has become an important guarantee of the success of urbanization. Exploring the commercial service facilities in a specific area of a city can help us understand the progress and trends of urban renewal in the area, provide a quantitative basis for evaluating the rationality of planning implementation, and facilitate an analysis of the effects of different factors on the regional development of a city (Schor et al. 2003. In this paper, we proposed a data processing and analysis method for studying the distribution and development pattern of urban commercial facilities based on customer reviews. In addition, based on road network constraints, we explored the patterns contained in customer reviews data, including patterns for the spatial distribution and spatial-temporal evolution of facilities as well as the number of facilities and degree of satisfaction.

Fission reactor based epithermal neutron irradiation facilities for routine clinical application in BNCT-Hatanaka memorial lecture

International Nuclear Information System (INIS)

Harling, Otto K.

2009-01-01

Based on experience gained in the recent clinical studies at MIT/Harvard, the desirable characteristics of epithermal neutron irradiation facilities for eventual routine clinical BNCT are suggested. A discussion of two approaches to using fission reactors for epithermal neutron BNCT is provided. This is followed by specific suggestions for the performance and features needed for high throughput clinical BNCT. An example of a current state-of-the-art, reactor based facility, suited for routine clinical use is discussed. Some comments are provided on the current status of reactor versus accelerator based epithermal neutron sources for BNCT. This paper concludes with a summary and a few personal observations on BNCT by the author.

Operationalising emergency care delivery in sub-Saharan Africa: consensus-based recommendations for healthcare facilities.

Science.gov (United States)

Calvello, Emilie J B; Tenner, Andrea G; Broccoli, Morgan C; Skog, Alexander P; Muck, Andrew E; Tupesis, Janis P; Brysiewicz, Petra; Teklu, Sisay; Wallis, Lee; Reynolds, Teri

2016-08-01

A major barrier to successful integration of acute care into health systems is the lack of consensus on the essential components of emergency care within resource-limited environments. The 2013 African Federation of Emergency Medicine Consensus Conference was convened to address the growing need for practical solutions to further implementation of emergency care in sub-Saharan Africa. Over 40 participants from 15 countries participated in the working group that focused on emergency care delivery at health facilities. Using the well-established approach developed in the WHO's Monitoring Emergency Obstetric Care, the workgroup identified the essential services delivered-signal functions-associated with each emergency care sentinel condition. Levels of emergency care were assigned based on the expected capacity of the facility to perform signal functions, and the necessary human, equipment and infrastructure resources identified. These consensus-based recommendations provide the foundation for objective facility capacity assessment in developing emergency health systems that can bolster strategic planning as well as facilitate monitoring and evaluation of service delivery. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Association of antenatal care with facility delivery and perinatal survival – a population-based study in Bangladesh

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Pervin Jesmin

2012-10-01

Full Text Available Abstract Background Antenatal Care (ANC during pregnancy can play an important role in the uptake of evidence-based services vital to the health of women and their infants. Studies report positive effects of ANC on use of facility-based delivery and perinatal mortality. However, most existing studies are limited to cross-sectional surveys with long recall periods, and generally do not include population-based samples. Methods This study was conducted within the Health and Demographic Surveillance System (HDSS of the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b in Matlab, Bangladesh. The HDSS area is divided into an icddr,b service area (SA where women and children receive care from icddr,b health facilities, and a government SA where people receive care from government facilities. In 2007, a new Maternal, Neonatal, and Child Health (MNCH program was initiated in the icddr,b SA that strengthened the ongoing maternal and child health services including ANC. We estimated the association of ANC with facility delivery and perinatal mortality using prospectively collected data from 2005 to 2009. Using a before-after study design, we also determined the role of ANC services on reduction of perinatal mortality between the periods before (2005 – 2006 and after (2008–2009 implementation of the MNCH program. Results Antenatal care visits were associated with increased facility-based delivery in the icddr,b and government SAs. In the icddr,b SA, the adjusted odds of perinatal mortality was about 2-times higher (odds ratio (OR 1.91; 95% confidence intervals (CI: 1.50, 2.42 among women who received ≤1 ANC compared to women who received ≥3 ANC visits. No such association was observed in the government SA. Controlling for ANC visits substantially reduced the observed effect of the intervention on perinatal mortality (OR 0.64; 95% CI: 0.52, 0.78 to non-significance (OR 0.81; 95% CI: 0.65, 1.01, when comparing cohorts before

Nuclear facilities of EdF's operational hot base of Tricastin. 2009 annual report

International Nuclear Information System (INIS)

2010-01-01

This annual report is established on account of article 21 of the 2006-686 French law from June 13, 2006, relative to the transparency and safety in the nuclear domain. It describes, first, the nuclear facilities of the EdF operational hot base of Tricastin, then, the measures taken to ensure their safety (personnel radioprotection, actions implemented for nuclear safety improvement, organisation in crisis situation, external and internal controls, technical assessment of the facilities), and finally the procedures of management of radioactive wastes. A glossary and the viewpoint of the Committee of Hygiene, safety and working conditions about the content of the document conclude the report. (J.S.)

Minnesota's Nursing Facility Performance-Based Incentive Payment Program: An Innovative Model for Promoting Care Quality

Science.gov (United States)

Cooke, Valerie; Arling, Greg; Lewis, Teresa; Abrahamson, Kathleen A.; Mueller, Christine; Edstrom, Lisa

2010-01-01

Purpose: Minnesota's Nursing Facility Performance-Based Incentive Payment Program (PIPP) supports provider-initiated projects aimed at improving care quality and efficiency. PIPP moves beyond conventional pay for performance. It seeks to promote implementation of evidence-based practices, encourage innovation and risk taking, foster collaboration…

PROOF as a Service on the Cloud: a Virtual Analysis Facility based on the CernVM ecosystem

CERN Document Server

Berzano, Dario; Buncic, Predrag; Charalampidis, Ioannis; Ganis, Gerardo; Lestaris, Georgios; Meusel, René

2014-01-01

PROOF, the Parallel ROOT Facility, is a ROOT-based framework which enables interactive parallelism for event-based tasks on a cluster of computing nodes. Although PROOF can be used simply from within a ROOT session with no additional requirements, deploying and configuring a PROOF cluster used to be not as straightforward. Recently great efforts have been spent to make the provisioning of generic PROOF analysis facilities with zero configuration, with the added advantages of positively affecting both stability and scalability, making the deployment operations feasible even for the end user. Since a growing amount of large-scale computing resources are nowadays made available by Cloud providers in a virtualized form, we have developed the Virtual PROOF-based Analysis Facility: a cluster appliance combining the solid CernVM ecosystem and PoD (PROOF on Demand), ready to be deployed on the Cloud and leveraging some peculiar Cloud features such as elasticity. We will show how this approach is effective both for sy...

Facility-Based Maternal Death in Western Africa: A Systematic Review

Directory of Open Access Journals (Sweden)

Nathali Gunawardena

2018-02-01

Full Text Available BackgroundFor exploring maternal death, supply and demand-side factors can be characterized by the three delays model developed by Thaddeus and Maine (1994. The model comprises delay in deciding to seek care (delay 1, delay in reaching the health facility (delay 2, and delay in receiving quality care once at the health facility (delay 3. Few studies have comprehensively dealt with the health systems delays that prevent the receipt of timely and appropriate obstetric care once a woman reaches a health facility (phase III delays. The objective of the present study was to identify facility-level barriers in West African health facilities.MethodsElectronic databases (Medline, cumulative index to nursing and allied health literature, Centre for Agriculture and Biosciences International Global Health, EMBASE were searched to identify original research articles from 1996 to 2016. Search terms (and synonyms related to (1 maternal health care (e.g., obstetric care, perinatal care, maternal health services; (2 facility level (e.g., maternity unit, health facility, phase III, hospital; and (3 Western Africa (e.g., Nigeria, Burkina Faso were combined. This review followed the preferred reporting items for systematic reviews and meta-analyses.ResultsOf the 2103 citations identified, 13 studies were eligible. Studies were conducted in Nigeria, Burkina Faso, Gambia, Guinea, Senegal, and Sierra Leone. 30 facility-level barriers were identified and grouped into 6 themes (human resources, supply and equipment, referral-related, infrastructure, cost-related, patient-related. The most obvious barriers included staff shortages, lack of maternal health services and procedures offered to patients, and lack of necessary medical equipment and supplies in the health-care facilities.ConclusionThis review emphasizes that phase I and phase II barriers are not the only factors preventing women from accessing proper emergency obstetric care. Health-care facilities in Western

Radiological Research Accelerator Facility

International Nuclear Information System (INIS)

Goldhagen, P.; Marino, S.A.; Randers-Pehrson, G.; Hall, E.J.

1986-01-01

The Radiological Research Accelerator Facility (RARAF) is based on a 4-MV Van de Graaff accelerator, which can be used to generate a variety of well-characterized radiation beams for research in radiobiology and radiological physics. It is part of the Radiological Research Laboratory (RRL), and its operation is supported as a National Facility by the US Department of Energy. RARAF is available to all potential users on an equal basis, with priorities based on the recommendations of a Scientific Advisory Committee. Facilities and services are provided to users, but the research projects themselves must be supported separately. This chapter presents a brief description of current experiments being carried out at RARAF and of the operation of the Facility from January through June, 1986. Operation of the Facility for all of 1985 was described in the 1985 Progress Report for RARAF. The experiments described here were supported by various Grants and Contracts from NIH and DOE and by the Statens Stralskyddsinstitut of Sweden

Facility Effluent Monitoring Plan for Pacific Northwest National Laboratory Balance-of-Plant Facilities

Energy Technology Data Exchange (ETDEWEB)

Ballinger, Marcel Y.; Gervais, Todd L.

2004-11-15

The Pacific Northwest National Laboratory (PNNL) operates a number of Research & Development (R&D) facilities for the U.S. Department of Energy (DOE) on the Hanford Site. Facility effluent monitoring plans (FEMPs) have been developed to document the facility effluent monitoring portion of the Environmental Monitoring Plan (DOE 2000) for the Hanford Site. Three of PNNL’s R&D facilities, the 325, 331, and 3720 Buildings, are considered major emission points for radionuclide air sampling, and individual FEMPs were developed for these facilities in the past. In addition, a balance-of-plant (BOP) FEMP was developed for all other DOE-owned, PNNL-operated facilities at the Hanford Site. Recent changes, including shutdown of buildings and transition of PNNL facilities to the Office of Science, have resulted in retiring the 3720 FEMP and combining the 331 FEMP into the BOP FEMP. This version of the BOP FEMP addresses all DOE-owned, PNNL-operated facilities at the Hanford Site, excepting the Radiochemical Processing Laboratory, which has its own FEMP because of the unique nature of the building and operations. Activities in the BOP facilities range from administrative to laboratory and pilot-scale R&D. R&D activities include both radioactive and chemical waste characterization, fluid dynamics research, mechanical property testing, dosimetry research, and molecular sciences. The mission and activities for individual buildings are described in Appendix A. Potential radioactive airborne emissions in the BOP facilities are estimated annually using a building inventory-based approach provided in federal regulations. Sampling at individual BOP facilities is based on a potential-to-emit assessment. Some of these facilities are considered minor emission points and thus are sampled routinely, but not continuously, to confirm the low emission potential. One facility, the 331 Life Sciences Laboratory, has a major emission point and is sampled continuously. Sampling systems are

Nuclear safety and radiation protection report of the Tricastin operational hot base nuclear facilities - 2013

International Nuclear Information System (INIS)

2014-01-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the Tricastin operational hot base facility (INB no. 157, Bollene, Vaucluse (FR)), a nuclear workshop for storage and maintenance and qualification operations on some EdF equipments. Then, the nuclear safety and radiation protection measures taken regarding the facility are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2013, if some, are reported as well as the effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facility is presented and sorted by type of waste, quantities and type of conditioning. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions

Ship Domain Model for Multi-ship Collision Avoidance Decision-making with COLREGs Based on Artificial Potential Field

Directory of Open Access Journals (Sweden)

TengFei Wang

2017-03-01

Full Text Available A multi-ship collision avoidance decision-making and path planning formulation is studied in a distributed way. This paper proposes a complete set of solutions for multi-ship collision avoidance in intelligent navigation, by using a top-to-bottom organization to structure the system. The system is designed with two layers: the collision avoidance decision-making and the path planning. Under the general requirements of the International Regulations for Preventing Collisions at Sea (COLREGs, the performance of distributed path planning decision-making for anti-collision is analyzed for both give-way and stand-on ships situations, including the emergency actions taken by the stand-on ship in case of the give-way ship’s fault of collision avoidance measures. The Artificial Potential Field method(APF is used for the path planning in details. The developed APF method combined with the model of ship domain takes the target ships’ speed and course in-to account, so that it can judge the moving characteristics of obstacles more accurately. Simulation results indicate that the system proposed can work effectiveness.

Event simulation based on three-fluid hydrodynamics for collisions at energies available at the Dubna Nuclotron-based Ion Collider Facility and at the Facility for Antiproton and Ion Research in Darmstadt

Science.gov (United States)

Batyuk, P.; Blaschke, D.; Bleicher, M.; Ivanov, Yu. B.; Karpenko, Iu.; Merts, S.; Nahrgang, M.; Petersen, H.; Rogachevsky, O.

2016-10-01

We present an event generator based on the three-fluid hydrodynamics approach for the early stage of the collision, followed by a particlization at the hydrodynamic decoupling surface to join to a microscopic transport model, ultrarelativistic quantum molecular dynamics, to account for hadronic final-state interactions. We present first results for nuclear collisions of the Facility for Antiproton and Ion Research-Nuclotron-based Ion Collider Facility energy scan program (Au+Au collisions, √{sN N}=4 -11 GeV ). We address the directed flow of protons and pions as well as the proton rapidity distribution for two model equations of state, one with a first-order phase transition and the other with a crossover-type softening at high densities. The new simulation program has the unique feature that it can describe a hadron-to-quark matter transition which proceeds in the baryon stopping regime that is not accessible to previous simulation programs designed for higher energies.

GIS-based approach for defining bioenergy facilities location: A case study in Northern Spain based on marginal delivery costs and resources competition between facilities

Energy Technology Data Exchange (ETDEWEB)

Panichelli, Luis; Gnansounou, Edgard [Laboratory of Energy Systems, Swiss Federal Institute of Technology, LASEN-ICARE-ENAC, Station 18, EPFL, CH-1015 Lausanne (Switzerland)

2008-04-15

This paper presents a GIS-based decision support system for selecting least-cost bioenergy locations when there is a significant variability in biomass farmgate price and when more than one bioenergy plant with a fixed capacity has to be placed in the region. The methodology tackles the resources competition problem between energy facilities through a location-allocation model based on least-cost biomass quantities. Whole system least delivery cost including intermediate bioenergy products is estimated. The methodology is based on a case study where forest wood residues (FWR) from final cuttings (FCs) are used to produce torrefied wood (TW) in two torrefaction plants (TUs) that supply a gasification unit (GU) in order to produce electricity. The provinces of Navarra, Bizkaia, Gipuzkoa, Alava, La Rioja, Cantabria and Burgos are assessed in order to find the best locations for settling down the TUs and the GU according to biomass availability, FWR and TW marginal delivery costs. (author)

Study on UPF Harmonic Current Detection Method Based on DSP

Energy Technology Data Exchange (ETDEWEB)

Zhao, H J [Northwestern Polytechnical University, Xi' an 710072 (China); Pang, Y F [Xi' an University of Technology, Xi' an 710048 (China); Qiu, Z M [Xi' an University of Technology, Xi' an 710048 (China); Chen, M [Northwestern Polytechnical University, Xi' an 710072 (China)

2006-10-15

Unity power factor (UPF) harmonic current detection method applied to active power filter (APF) is presented in this paper. The intention of this method is to make nonlinear loads and active power filter in parallel to be an equivalent resistance. So after compensation, source current is sinusoidal, and has the same shape of source voltage. Meanwhile, there is no harmonic in source current, and the power factor becomes one. The mathematic model of proposed method and the optimum project for equivalent low pass filter in measurement are presented. Finally, the proposed detection method applied to a shunt active power filter experimental prototype based on DSP TMS320F2812 is developed. Simulation and experiment results indicate the method is simple and easy to implement, and can obtain the real-time calculation of harmonic current exactly.

High-power light-emitting diode based facility for plant cultivation

Energy Technology Data Exchange (ETDEWEB)

Tamulaitis, G [Institute of Materials Science and Applied Research, Vilnius University, Sauletekio al. 9-III, LT-10222 Vilnius (Lithuania); Duchovskis, P [Lithuanian Institute of Horticulture, Babtai, LT-54333 Kaunas District (Lithuania); Bliznikas, Z [Institute of Materials Science and Applied Research, Vilnius University, Sauletekio al. 9-III, LT-10222 Vilnius (Lithuania); Breive, K [Institute of Materials Science and Applied Research, Vilnius University, Sauletekio al. 9-III, LT-10222 Vilnius (Lithuania); Ulinskaite, R [Lithuanian Institute of Horticulture, Babtai, LT-54333 Kaunas District (Lithuania); Brazaityte, A [Lithuanian Institute of Horticulture, Babtai, LT-54333 Kaunas District (Lithuania); Novickovas, A [Institute of Materials Science and Applied Research, Vilnius University, Sauletekio al. 9-III, LT-10222 Vilnius (Lithuania); Zukauskas, A [Institute of Materials Science and Applied Research, Vilnius University, Sauletekio al. 9-III, LT-10222 Vilnius (Lithuania)

2005-09-07

Based on perspectives of the development of semiconductor materials systems for high-power light-emitting diodes (LEDs), an illumination facility for greenhouse plant cultivation was designed with the dominating 640 nm photosynthetically active component delivered by AlGaInP LEDs and supplementary components from AlGaN (photothropic action, 455 nm) and AlGaAs (photosynthetic 660 nm and photomorphogenetic 735 nm) LEDs. Photosynthesis intensity, photosynthetic productivity and growth morphology as well as chlorophyll and phytohormone concentrations were investigated in radish and lettuce grown in phytotron chambers under the LED-based illuminators and under high-pressure sodium (HPS) lamps with an equivalent photon flux density. Advantages of the high-power LED-based illuminators over conventional HPS lamps, applicability of AlGaInP LEDs for photosynthesis and control of plant growth by circadian manipulation of a relatively weak far-red component were demonstrated.

High-power light-emitting diode based facility for plant cultivation

International Nuclear Information System (INIS)

Tamulaitis, G; Duchovskis, P; Bliznikas, Z; Breive, K; Ulinskaite, R; Brazaityte, A; Novickovas, A; Zukauskas, A

2005-01-01

Based on perspectives of the development of semiconductor materials systems for high-power light-emitting diodes (LEDs), an illumination facility for greenhouse plant cultivation was designed with the dominating 640 nm photosynthetically active component delivered by AlGaInP LEDs and supplementary components from AlGaN (photothropic action, 455 nm) and AlGaAs (photosynthetic 660 nm and photomorphogenetic 735 nm) LEDs. Photosynthesis intensity, photosynthetic productivity and growth morphology as well as chlorophyll and phytohormone concentrations were investigated in radish and lettuce grown in phytotron chambers under the LED-based illuminators and under high-pressure sodium (HPS) lamps with an equivalent photon flux density. Advantages of the high-power LED-based illuminators over conventional HPS lamps, applicability of AlGaInP LEDs for photosynthesis and control of plant growth by circadian manipulation of a relatively weak far-red component were demonstrated

Hysteresis Control for Shunt Active Power Filter under Unbalanced Three-Phase Load Conditions

Directory of Open Access Journals (Sweden)

Z. Chelli

2015-01-01

Full Text Available This paper focuses on a four-wire shunt active power filter (APF control scheme proposed to improve the performance of the APF. This filter is used to compensate harmonic distortion in three-phase four-wire systems. Several harmonic suppression techniques have been widely proposed and applied to minimize harmonic effects. The proposed control scheme can compensate harmonics and reactive power of the nonlinear loads simultaneously. This approach is compared to the conventional shunt APF reference compensation strategy. The developed algorithm is validated by simulation tests using MATLAB Simulink. The obtained results have demonstrated the effectiveness of the proposed scheme and confirmed the theoretical developments for balanced and unbalanced nonlinear loads.

Accelerator based research facility as an inter university centre

International Nuclear Information System (INIS)

Mehta, G.K.

1995-01-01

15 UD pelletron has been operating as a user facility from July 1991. It is being utilised by a large number of universities and other institutions for research in basic Nuclear Physics, Materials Science, Atomic Physics, Radiobiology and Radiation Chemistry. There is an on-going programme for augmenting the accelerator facilities by injecting Pelletron beams into superconducting linear accelerator modules. Superconducting niobium resonator is being developed in Argonne National Laboratory as a joint collaborative effort. All other things such as cryostats, rf instrumentation, cryogenic distribution system, computer control etc are being done indigenously. Research facilities, augmentation plans and the research being conducted by the universities in various disciplines are described. (author)

Selective adsorption of molybdenum(VI) from Mo-Re bearing effluent by chemically modified astringent persimmon

Energy Technology Data Exchange (ETDEWEB)

Xiong Ying, E-mail: xiongying_1977@hotmail.com [School of Chemistry, Key Laboratory of Rare-scattered Elements of Liaoning Province, Liaoning University, Shenyang 110036 (China); Wang Haitao; Lou Zhenning; Shan Weijun; Xing Zhiqiang; Deng Guichun [School of Chemistry, Key Laboratory of Rare-scattered Elements of Liaoning Province, Liaoning University, Shenyang 110036 (China); Wu Dongbei [Department of Chemistry, Tongji University, 200092 (China); Fang Dawei [School of Chemistry, Key Laboratory of Rare-scattered Elements of Liaoning Province, Liaoning University, Shenyang 110036 (China); Biswas, Biplob Kumar [Department of Applied Chemistry, Saga University, Honjo 1, Saga 840-8502 (Japan); Department of Applied Chemistry and Chemical Engineering, Jessore Science and Technology University, Jessore (Bangladesh)

2011-02-28

Graphical abstract: The use of persimmon for the recovery of Mo(VI) from aqueous chloride medium was investigated. The excellent adsorption characteristics for Mo(VI) were confirmed by adsorption and elution tests using a column packed with the APF gel. Research highlights: {yields} Astringent persimmon was chemically cross-linked by formaldehyde to obtain a novel kind of adsorption gel. By comparing with the adsorption of some other metal ions, especially for Re(VII), this new gel exhibited selectivity only for molybdenum with a remarkably high capacity for Mo(VI) (1.05 mol/kg dry gel). {yields} The adsorption mechanisms of molybdenum on the astringent persimmon gel have been determined for deferent molybdenum species. And, the endothermic adsorption process followed pseudo-second order kinetics, and the adsorption behavior obeys the Langmuir mode. {yields} The excellent adsorption characteristics for Mo(VI) were confirmed by adsorption and elution tests using a column packed with the APF gel, especially from an actual industrial waste effluent. - Abstract: Astringent persimmon was chemically cross-linked by formaldehyde to obtain a novel kind of adsorption gel, which was named as APF gel. The adsorption behaviors of Mo(VI) and Re(VII) along with other coexisting metals onto the APF gel were studied in the present paper. The APF gel was found to be effective for the adsorption of Mo(VI) while the gel is almost completely inert toward rhenium and calcium over the whole hydrochloric acid concentration region. The APF gel has a low affinity for iron, copper, lead, nickel, manganese and zinc ions when the concentration of HCl is higher than 1 mol/L. The gel exhibited selectivity only for Mo(VI) with a remarkably high adsorption capacity 1.05 mol/kg, and the adsorption behavior obeys the Langmuir model. According to the thermodynamic and kinetic studies, the endothermic adsorption process followed pseudo-second order kinetics. Also, its excellent adsorption

Variation on Molecular Structure, Crystallinity, and Optical Properties of Dentin Due to Nd:YAG Laser and Fluoride Aimed at Tooth Erosion Prevention

Science.gov (United States)

Freitas, Anderson Z.; Bachmann, Luciano; Benetti, Carolina; Ana, Patricia A.

2018-01-01

This in vitro study evaluated the compositional, crystalline, and morphological effects promoted by Nd:YAG laser on root dentin, and verified the effects of laser and topical acidulated phosphate fluoride application (APF-gel) on dentin erosion. 180 bovine dentin slabs were randomized into 4 groups (n = 45): G1–untreated, G2–APF-gel (1.23% F−, 4 min), G3–Nd:YAG (1064 nm, 84.9 J/cm2, 10 Hz), and G4–APF-gel application followed by Nd:YAG laser irradiation. The compositional, crystalline, and morphological effects promoted by treatments were investigated on five samples of each experimental group. The other samples were submitted to a 5-day, 10-day, or 15-day erosive and abrasive demineralization and remineralization cycling in order to create erosion lesions. The area and depth of lesions, as well as the optical attenuation coefficient, were assessed, and all data were statistically analysed (p laser promoted the reduction of carbonate, the formation of tetracalcium phosphate, as well as the melting and recrystallization of the dentin surface. Laser significantly decreased the area and depth of erosion lesions and altered the optical attenuation coefficient when compared to untreated and APF-gel groups, but the association of APF-gel and laser did not promote an additional effect. Nd:YAG laser irradiation can be a promissory treatment to prevent dentin erosion and the abrasion process. PMID:29389868

Beam based alignment at the KEK accelerator test facility

International Nuclear Information System (INIS)

Ross, M.; Nelson, J.; Woodley, M.; Wolski, A.

2002-01-01

The KEK Accelerator Test Facility (ATF) damping ring is a prototype low emittance source for the NLC/JLC linear collider. To achieve the goal normalized vertical emittance gey = 20 nm-rad, magnet placement accuracy better than 30 mm must be achieved. Accurate beam-based alignment (BBA) is required. The ATF arc optics uses a FOBO cell with two horizontally focusing quadrupoles, two sextupoles and a horizontally defocusing gradient dipole, all of which must be aligned with BBA. BBA at ATF uses the quadrupole and sextupole trim windings to find the trajectory through the center of each magnet. The results can be interpreted to assess the accuracy of the mechanical alignment and the beam position monitor offsets

Responsible Adult Culture (RAC): Cognitive and Behavioral Changes at a Community-Based Correctional Facility

Science.gov (United States)

Devlin, Renee S.; Gibbs, John C.

2010-01-01

This article examined cognitive and behavioral changes among participants in Responsible Adult Culture (RAC), a cognitive-behavioral (especially, cognitive restructuring) treatment program in use at the Franklin County Community-Based Correctional Facility (CBCF). Participants were adult felony offenders (approximately three-fourths male). A…

A durability analysis of the Cascad facility based on feedback obtained after 10 years of operation

International Nuclear Information System (INIS)

Samoel, R.; Canas, D.; Henry, H.; Battesti, P.

1999-01-01

The CASCAD facility at the nuclear research centre in Cadarache is a dry storage facility for spent fuel that has been placed in a vault. Feedback on its design and performance after 10 years of operation was obtained in order to identify the factors limiting its life time. This assessment corresponds to a durability analysis based on a combination of dependability methods. This is a critical analysis identifying the risks involving failure of the components when they are subjected to internal and external disturbances (aging, technology obsolescence, etc.). The measures to be implemented to extend the life time of the facility are subsequently enumerated. A proposed synthesis or 'logic diagram' of the analysis is also presented. (authors)

Facility Service Market an European Overview based on EU Statistics

Directory of Open Access Journals (Sweden)

Alexander Redlein

2017-01-01

Full Text Available The macro-economic impact of facility management and facility services in special was not scientifically analysed by now. Some studies analysed single countries but were mainly lacking solid data. Especially a Pan European comparison is lacking. This paper presents the results of an in depth analysis of the Eurostat figures. It compares the facility service industry with other industries in particular the construction industry. It also compares the largest European economies (Germany, France and Italy. The study concentrates on the outsourced services only, as these are listed in the European Statistics. The results show big differences between the European countries. It also highlights that the facility service industry is the third largest regarding number of employees and the fourth largest regarding value added.

Facility and home based HIV Counseling and Testing: a comparative analysis of uptake of services by rural communities in southwestern Uganda

Directory of Open Access Journals (Sweden)

Guerra Ranieri

2011-03-01

Full Text Available Abstract Background In Uganda, public human immunodeficiency virus (HIV Voluntary Counseling and Testing (VCT services are mainly provided through the facility based model, although the home based approach is being promoted as a strategy for improving access to VCT. However the uptake of VCT varies according to service delivery model and is influenced by a number of factors. The aim of this study therefore, was to compare predictors for uptake of facility and home based VCT in a rural context. Methods A longitudinal study with cross-sectional investigative phases was conducted at two sites (Rugando and Kabingo in southwestern Uganda between November 2007 (baseline and March 2008 (follow up. During the baseline visit, facility based VCT was offered at the main health centre in Rugando while home based VCT was offered at the household level in Kabingo and a mixed survey questionnaire administered to the respondents. The results presented in this paper are derived from only the baseline data. Results Nine hundred ninety four (994 respondents were interviewed, of whom 500 received facility based VCT in Rugando and 494 home based VCT in Kabingo during the baseline visit. The respondents had a mean age of 32.2 years (SD 10.9 and were mainly female (68 percent. Clients who received facility based VCT were less likely to be residents of the more rural households (adjusted Odds Ratio (aOR = 0.14, 95% CI 0.07, 0.22. The clients who received home based VCT were less likely to report having an STI symptom (aOR = 0.63, 95% CI 0.46, 0.86, and more likely to be worried about discrimination if they contracted AIDS (aOR = 1.78, 95% CI 1.22, 2.61. Conclusion The uptake of VCT provided through either the facility or home based models is influenced by client characteristics such as proximity to service delivery points, HIV related symptoms, and fear of discrimination in rural Uganda. Interventions that seek to improve uptake of VCT should provide potential clients

Women's experiences of mistreatment during childbirth: A comparative view of home- and facility-based births in Pakistan.

Science.gov (United States)

Hameed, Waqas; Avan, Bilal Iqbal

2018-01-01

Respectful and dignified healthcare is a fundamental right for every woman. However, many women seeking childbirth services, especially those in low-income countries such as Pakistan, are mistreated by their birth attendants. The aim of this epidemiological study was to estimate the prevalence of mistreatment and types of mistreatment among women giving birth in facility- and home-based settings in Pakistan in order to address the lack of empirical evidence on this topic. The study also examined the association between demographics (socio-demographic, reproductive history and empowerment status) and mistreatment, both in general and according to birth setting (whether home- or facility-based). In phase one, we identified 24 mistreatment indicators through an extensive literature review. We then pre-tested these indicators and classified them into seven behavioural types. During phase two, the survey was conducted (April-May 2013) in 14 districts across Pakistan. A total of 1,334 women who had given birth at home or in a healthcare facility over the past 12 months were interviewed. Linear regression analysis was employed for the full data set, and for facility- and home-based births separately, using Stata version 14.1. There were no significant differences in manifestations of mistreatment between facility- and home-based childbirths. Approximately 97% of women reported experiencing at least one disrespectful and abusive behaviour. Experiences of mistreatment by type were as follows: non-consented care (81%); right to information (72%); non-confidential care (69%); verbal abuse (35%); abandonment of care (32%); discriminatory care (15%); and physical abuse (15%). In overall analysis, experience of mistreatment was lower among women who were unemployed (β = -1.17, 95% CI -1.81, -0.53); and higher among less empowered women (β = 0.11, 95% CI 0.06, 0.16); and those assisted by a traditional birth attendant as opposed to a general physician (β = 0.94, 95% CI 0.13, 1

Teaching ergonomics to nursing facility managers using computer-based instruction.

Science.gov (United States)

Harrington, Susan S; Walker, Bonnie L

2006-01-01

This study offers evidence that computer-based training is an effective tool for teaching nursing facility managers about ergonomics and increasing their awareness of potential problems. Study participants (N = 45) were randomly assigned into a treatment or control group. The treatment group completed the ergonomics training and a pre- and posttest. The control group completed the pre- and posttests without training. Treatment group participants improved significantly from 67% on the pretest to 91% on the posttest, a gain of 24%. Differences between mean scores for the control group were not significant for the total score or for any of the subtests.

21 CFR 1271.190 - Facilities.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Facilities. 1271.190 Section 1271.190 Food and... CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.190 Facilities. (a) General. Any facility used in the manufacture of HCT/Ps must be of suitable size, construction, and location to prevent...

Higher balance task demands are associated with an increase in individual alpha peak frequency

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Thorben eHülsdünker

2016-01-01

Full Text Available Balance control is fundamental for most daily motor activities, and its impairment is associated with an increased risk of falling. Growing evidence suggests the human cortex is essentially contributing to the control of standing balance. However, the exact mechanisms remain unclear and need further investigation. In a previous study we introduced a new protocol to identify electrocortical activity associated with performance of different continuous balance tasks with the eyes opened. The aim of this study was to extend our previous results by investigating the individual alpha peak frequency (iAPF, a neurophysiological marker of thalamo-cortical information transmission, which remained unconsidered so far in balance research. Thirty-seven subjects completed nine balance tasks varying in surface stability and base of support. Electroencephalography (EEG was recorded from 32 scalp locations throughout balancing with the eyes closed to ensure reliable identification of the iAPF. Balance performance was quantified as the sum of anterior-posterior and medio-lateral movements of the supporting platform. The iAPF, as well as power in the theta, lower alpha and upper alpha frequency bands were determined for each balance task after applying an ICA-based artifact rejection procedure. Higher demands on balance control were associated with a global increase in iAPF and a decrease in lower alpha power. These results may indicate increased thalamo-cortical information transfer and general cortical activation, respectively. In addition, a significant increase in upper alpha activity was observed in the fronto-central region whereas it decreased in the centro-parietal region. Furthermore, midline theta increased with higher task demands probably indicating activation of error detection/processing mechanisms. IAPF as well as theta and alpha power were correlated with platform movements. The results provide new insights into spectral and spatial characteristics

Do knowledge infrastructure facilities support Evidence-Based Practice in occupational health? An exploratory study across countries among occupational physicians enrolled on Evidence-Based Medicine courses

Directory of Open Access Journals (Sweden)

van Dijk Frank JH

2009-01-01

Full Text Available Abstract Background Evidence-Based Medicine (EBM is an important method used by occupational physicians (OPs to deliver high quality health care. The presence and quality of a knowledge infrastructure is thought to influence the practice of EBM in occupational health care. This study explores the facilities in the knowledge infrastructure being used by OPs in different countries, and their perceived importance for EBM practice. Methods Thirty-six OPs from ten countries, planning to attend an EBM course and to a large extent recruited via the European Association of Schools of Occupational Medicine (EASOM, participated in a cross-sectional study. Results Research and development institutes, and knowledge products and tools are used by respectively more than 72% and more than 80% of the OPs and they are rated as being important for EBM practice (more than 65 points (range 0–100. Conventional knowledge access facilities, like traditional libraries, are used often (69% but are rated as less important (46.8 points (range 0–100 compared to the use of more novel facilities, like question-and-answer facilities (25% that are rated as more important (48.9 points (range 0–100. To solve cases, OPs mostly use non evidence-based sources. However, they regard the evidence-based sources that are not often used, e.g. the Cochrane library, as important enablers for practising EBM. The main barriers are lack of time, payment for full-text articles, language barrier (most texts are in English, and lack of skills and support. Conclusion This first exploratory study shows that OPs use many knowledge infrastructure facilities and rate them as being important for their EBM practice. However, they are not used to use evidence-based sources in their practice and face many barriers that are comparable to the barriers physicians face in primary health care.

Mammography Facilities

Data.gov (United States)

U.S. Department of Health & Human Services — The Mammography Facility Database is updated periodically based on information received from the four FDA-approved accreditation bodies: the American College of...

DOE Order 5480.28 Hanford facilities database

Energy Technology Data Exchange (ETDEWEB)

Hayenga, J.L., Westinghouse Hanford

1996-09-01

This document describes the development of a database of DOE and/or leased Hanford Site Facilities. The completed database will consist of structure/facility parameters essential to the prioritization of these structures for natural phenomena hazard vulnerability in compliance with DOE Order 5480.28, `Natural Phenomena Hazards Mitigation`. The prioritization process will be based upon the structure/facility vulnerability to natural phenomena hazards. The ACCESS based database, `Hanford Facilities Site Database`, is generated from current Hanford Site information and databases.

Radiation safety training for accelerator facilities

International Nuclear Information System (INIS)

Trinoskey, P.A.

1997-02-01

In November 1992, a working group was formed within the U.S. Department of Energy's (DOE's) accelerator facilities to develop a generic safety training program to meet the basic requirements for individuals working in accelerator facilities. This training, by necessity, includes sections for inserting facility-specific information. The resulting course materials were issued by DOE as a handbook under its technical standards in 1996. Because experimenters may be at a facility for only a short time and often at odd times during the day, the working group felt that computer-based training would be useful. To that end, Lawrence Livermore National Laboratory (LLNL) and Argonne National Laboratory (ANL) together have developed a computer-based safety training program for accelerator facilities. This interactive course not only enables trainees to receive facility- specific information, but time the training to their schedule and tailor it to their level of expertise

Utility of health facility-based malaria data for malaria surveillance.

Directory of Open Access Journals (Sweden)

Yaw A Afrane

Full Text Available Currently, intensive malaria control programs are being implemented in Africa to reduce the malaria burden. Clinical malaria data from hospitals are valuable for monitoring trends in malaria morbidity and for evaluating the impacts of these interventions. However, the reliability of hospital-based data for true malaria incidence is often questioned because of diagnosis accuracy issues and variation in access to healthcare facilities among sub-groups of the population. This study investigated how diagnosis and treatment practices of malaria cases in hospitals affect reliability of hospital malaria data.The study was undertaken in health facilities in western Kenya. A total of 3,569 blood smears were analyzed after being collected from patients who were requested by clinicians to go to the hospital's laboratory for malaria testing. We applied several quality control measures for clinical malaria diagnosis. We compared our slide reading results with those from the hospital technicians. Among the 3,390 patients whose diagnoses were analyzed, only 36% had clinical malaria defined as presence of any level of parasitaemia and fever. Sensitivity and specificity of clinicians' diagnoses were 60.1% (95% CI: 61.1-67.5 and 75.0% (95% CI: 30.8-35.7, respectively. Among the 980 patients presumptively treated with an anti-malarial by the clinicians without laboratory diagnosis, only 47% had clinical malaria.These findings revealed substantial over-prescription of anti-malarials and misdiagnosis of clinical malaria. More than half of the febrile cases were not truly clinical malaria, but were wrongly diagnosed and treated as such. Deficiency in malaria diagnosis makes health facility data unreliable for monitoring trends in malaria morbidity and for evaluating impacts of malaria interventions. Improving malaria diagnosis should be a top priority in rural African health centers.

Hanford Surplus Facilities Program plan

International Nuclear Information System (INIS)

Hughes, M.C.; Wahlen, R.K.; Winship, R.A.

1989-09-01

The Hanford Surplus Facilities Program is responsible for the safe and cost-effective surveillance, maintenance, and decommissioning of surplus facilities at the Hanford Site. The management of these facilities requires a surveillance and maintenance program to keep them in a safe condition and development of a plan for ultimate disposition. Criteria used to evaluate each factor relative to decommissioning are based on the guidelines presented by the US Department of Energy-Richland Operations Office, Defense Facilities Decommissioning Program Office, and are consistent with the Westinghouse Hanford Company commitment to decommission the Hanford Site retired facilities in the safest and most cost-effective way achievable. This document outlines the plan for managing these facilities to the end of disposition

Feasibility Study of SSTO Base Heating Simulation in Pulsed-Type Facilities

Science.gov (United States)

Park, Chung Sik; Sharma, Surendra; Edwards, Thomas A. (Technical Monitor)

1995-01-01

A laboratory simulation of the base heating environment of the proposed reusable Single-Stage-To-Orbit vehicle during its ascent flight was proposed. The rocket engine produces CO2 and H2, which are the main combustible components of the exhaust effluent. The burning of these species, known as afterburning, enhances the base region gas temperature as well as the base heating. To determine the heat flux on the SSTO vehicle, current simulation focuses on the thermochemistry of the afterburning, thermophysical properties of the base region gas, and ensuing radiation from the gas. By extrapolating from the Saturn flight data, the Damkohler number for the afterburning of SSTO vehicle is estimated to be of the order of 10. The limitations on the material strengths limit the laboratory simulation of the flight Damkohler number as well as other flow parameters. A plan is presented in impulse facilities using miniature rocket engines which generate the simulated rocket plume by electric ally-heating a H2/CO2 mixture.

Radioactive wastes. Safety of storage facilities

International Nuclear Information System (INIS)

Devillers, Ch.

2001-01-01

A radioactive waste storage facility is designed in a way that ensures the isolation of wastes with respect to the biosphere. This function comprises the damping of the gamma and neutron radiations from the wastes, and the confinement of the radionuclides content of the wastes. The safety approach is based on two time scales: the safety of the insulation system during the main phase of radioactive decay, and the assessment of the radiological risks following this phase. The safety of a surface storage facility is based on a three-barrier concept (container, storage structures, site). The confidence in the safety of the facility is based on the quality assurance of the barriers and on their surveillance and maintenance. The safety of a deep repository will be based on the site quality, on the design and construction of structures and on the quality of the safety demonstration. This article deals with the safety approach and principles of storage facilities: 1 - recall of the different types of storage facilities; 2 - different phases of the life of a storage facility and regulatory steps; 3 - safety and radiation protection goals (time scales, radiation protection goals); 4 - safety approach and principles of storage facilities: safety of the isolation system (confinement system, safety analysis, scenarios, radiological consequences, safety principles), assessment of the radiation risks after the main phase of decay; 5 - safety of surface storage facilities: safety analysis of the confinement system of the Aube plant (barriers, scenarios, modeling, efficiency), evaluation of radiological risks after the main phase of decay; experience feedback of the Manche plant; variants of surface storage facilities in France and abroad (very low activity wastes, mine wastes, short living wastes with low and average activity); 6 - safety of deep geological disposal facilities: legal framework of the French research; international context; safety analysis of the confinement system

VizieR Online Data Catalog: Radial velocities for the HD 3167 system (Christiansen+, 2017)

Science.gov (United States)

Christiansen, J. L.; Vanderburg, A.; Burt, J.; Fulton, B. J.; Batygin, K.; Benneke, B.; Brewer, J. M.; Charbonneau, D.; Ciardi, D. R.; Cameron, A. C.; Coughlin, J. L.; Crossfield, I. J. M.; Dressing, C.; Greene, T. P.; Howard, A. W.; Latham, D. W.; Molinari, E.; Mortier, A.; Mullally, F.; Pepe, F.; Rice, K.; Sinukoff, E.; Sozzetti, A.; Thompson, S. E.; Udry, S.; Vogt, S. S.; Barman, T. S.; Batalha, N. E.; Bouchy, F.; Buchhave, L. A.; Butler, R. P.; Cosentino, R.; Dupuy, T. J.; Ehrenreich, D.; Fiorenzano, A.; Hansen, B. M. S.; Henning, T.; Hirsch, L.; Holden, B. P.; Isaacson, H. T.; Johnson, J. A.; Knutson, H. A.; Kosiarek, M.; Lopez-Morales, M.; Lovis, C.; Malavolta, L.; Mayor, M.; Micela, G.; Motalebi, F.; Petigura, E.; Phillips, D. F.; Piotto, G.; Rogers, L. A.; Sasselov, D.; Schlieder, J. E.; Segransan, D.; Watson, C. A.; Weiss, L. M.

2018-06-01

The final data set includes observations obtained with Keck/HIRES, Automated Planet Finder (APF)/Levy, and HARPS-N. Our observational setup for both Keck/HIRES and the APF/Levy was essentially identical to those described in Fulton et al. (2016, J/ApJ/830/46) and Burt et al. (2014ApJ...789..114B). We collected a total of 60 RV measurements using Keck/HIRES (Vogt et al. 1994SPIE.2198..362V), and 116 measurements using the Levy Spectrograph on the APF (Radovan et al. 2014SPIE.9145E..2BR; Vogt et al. 2014PASP..126..359V) at Lick Observatory between 2016 July 7 and 2016 December 2. We also observed HD 3167 with the HARPS-N spectrograph (Cosentino et al. 2012SPIE.8446E..1VC) located at the 3.58 m Telescopio Nazionale Galileo on the island of La Palma, Spain. HARPS-N is a stabilized spectrograph designed for precise RV measurements. We observed HD 3167 76 times between 2016 July 7 (independently beginning the same night as the HIRES/APF campaign) and 2016 December 7, obtaining high-resolution optical spectra with a spectral resolving power of R=115000. (1 data file).

Production and functional characterisation of antioxidative hydrolysates from corn protein via enzymatic hydrolysis and ultrafiltration.

Science.gov (United States)

Zhou, Kequan; Sun, Shi; Canning, Corene

2012-12-01

Corn protein was hydrolysed by three microbial proteases and further separated by sequential ultra-filtration to 12 hydrolysate fractions which were investigated for free radical scavenging capacity and chelating activity. The oxygen radical absorbance capacity (ORAC) of the hydrolysates varied significantly between 65.6 and 191.4μmoles Trolox equivalents (TE)/g dried weight with a small peptide fraction (NP-F3) produced by neutral protease (NP) possessing the highest antioxidant activity. The 1,1-diphenyl-2-picrylhydrazyl radical (DPPH()) scavenging activities of the hydrolysate fractions also varied significantly between 18.4 and 38.7μmoles TE/g. Two fractions (AP-F2 and AP-F3) produced by alkaline protease (AP) showed the strongest activity. However, no significant difference was detected on the chelating activity of the fractions. NP-F3, AP-F2, and AP-F3 were incorporated into ground beef to determine their effects on lipid oxidation during 15-day storage period. NP-F3 was the only fraction that inhibited lipid oxidation at both 250 and 500μg/g levels by as much as 52.9%. Copyright © 2012 Elsevier Ltd. All rights reserved.

Risk-based investment trade-off related to building facility management

Energy Technology Data Exchange (ETDEWEB)

Taillandier, F. [Departement TIDS, Centre Scientifique et Technique du Batiment, 06904 Sophia Antipolis (France); Laboratoire Optimisation de la conception et Ingenierie de l' environnement, Polytech' Savoie, Universite de Savoie, 73376 Le Bourget du lac (France)], E-mail: franck.taillandier@univ-savoie.fr; Sauce, G. [Laboratoire Optimisation de la conception et Ingenierie de l' environnement, Polytech' Savoie, Universite de Savoie, 73376 Le Bourget du lac (France); Bonetto, R. [Departement TIDS, Centre Scientifique et Technique du Batiment, 06904 Sophia Antipolis (France)

2009-04-15

Due to his or her profession, any building facility manager has to face many decision-making situations. One of the most important to be mentioned is the arbitration of a multi-year maintenance plan for buildings. Deciding between proposed maintenance actions, according to several constraints, so as to aim at satisfying corporate strategy is a complex choice. Risk approaches can be particularly effective because of their ability to handle complexity and uncertainties. The problem is then to be able to propose a method considering risks, adapted to the specific context of building facility management. Our method, regarded as a traditional approach, includes needed resources (i.e. costs) according to constraints (i.e. budget), but it also considers several risk domains (safety, technical preservation, client satisfaction, etc.), through the consequences (gain and loss). It proposes an ergonomic arbitration system based on filters following two complementary approaches: a selection of the fundamental actions and then an optimization of the plan (in a global view). The aim, for decision-makers, is to build their own solution by testing multiple angles of vision in simulation logic. This article presents the principles of the method, illustrated by an example of a real case conducted for a leading French company.

Risk-based investment trade-off related to building facility management

International Nuclear Information System (INIS)

Taillandier, F.; Sauce, G.; Bonetto, R.

2009-01-01

Due to his or her profession, any building facility manager has to face many decision-making situations. One of the most important to be mentioned is the arbitration of a multi-year maintenance plan for buildings. Deciding between proposed maintenance actions, according to several constraints, so as to aim at satisfying corporate strategy is a complex choice. Risk approaches can be particularly effective because of their ability to handle complexity and uncertainties. The problem is then to be able to propose a method considering risks, adapted to the specific context of building facility management. Our method, regarded as a traditional approach, includes needed resources (i.e. costs) according to constraints (i.e. budget), but it also considers several risk domains (safety, technical preservation, client satisfaction, etc.), through the consequences (gain and loss). It proposes an ergonomic arbitration system based on filters following two complementary approaches: a selection of the fundamental actions and then an optimization of the plan (in a global view). The aim, for decision-makers, is to build their own solution by testing multiple angles of vision in simulation logic. This article presents the principles of the method, illustrated by an example of a real case conducted for a leading French company

Optimized Aircraft Electric Control System Based on Adaptive Tabu Search Algorithm and Fuzzy Logic Control

Directory of Open Access Journals (Sweden)

Saifullah Khalid

2016-09-01

Full Text Available Three conventional control constant instantaneous power control, sinusoidal current control, and synchronous reference frame techniques for extracting reference currents for shunt active power filters have been optimized using Fuzzy Logic control and Adaptive Tabu search Algorithm and their performances have been compared. Critical analysis of Comparison of the compensation ability of different control strategies based on THD and speed will be done, and suggestions will be given for the selection of technique to be used. The simulated results using MATLAB model are presented, and they will clearly prove the value of the proposed control method of aircraft shunt APF. The waveforms observed after the application of filter will be having the harmonics within the limits and the power quality will be improved.

Ocean robotics: 21st century sustainable science & marine resource management

CSIR Research Space (South Africa)

Swart, S

2015-10-01

Full Text Available marine robots? Swart et al., 2012 The CSIR Glider Fleet 14 GLIDERS: 5 PROFILING & 4 SURFACE GLIDERS = Glider deployment & ship CTD station = ship based underway measurements September 2012 – March 2013 Gough&Is. STF SAF APF G o u g h / T r i...

Advanced reactor experimental facilities

International Nuclear Information System (INIS)

Amri, A.; Papin, J.; Uhle, J.; Vitanza, C.

2010-01-01

For many years, the NEA has been examining advanced reactor issues and disseminating information of use to regulators, designers and researchers on safety issues and research needed. Following the recommendation of participants at an NEA workshop, a Task Group on Advanced Reactor Experimental Facilities (TAREF) was initiated with the aim of providing an overview of facilities suitable for carrying out the safety research considered necessary for gas-cooled reactors (GCRs) and sodium fast reactors (SFRs), with other reactor systems possibly being considered in a subsequent phase. The TAREF was thus created in 2008 with the following participating countries: Canada, the Czech Republic, Finland, France, Germany, Hungary, Italy, Japan, Korea and the United States. In a second stage, India provided valuable information on its experimental facilities related to SFR safety research. The study method adopted entailed first identifying high-priority safety issues that require research and then categorizing the available facilities in terms of their ability to address the safety issues. For each of the technical areas, the task members agreed on a set of safety issues requiring research and established a ranking with regard to safety relevance (high, medium, low) and the status of knowledge based on the following scale relative to full knowledge: high (100%-75%), medium (75 - 25%) and low (25-0%). Only the issues identified as being of high safety relevance and for which the state of knowledge is low or medium were included in the discussion, as these issues would likely warrant further study. For each of the safety issues, the TAREF members identified appropriate facilities, providing relevant information such as operating conditions (in- or out-of reactor), operating range, description of the test section, type of testing, instrumentation, current status and availability, and uniqueness. Based on the information collected, the task members assessed prospects and priorities

Reflooding phenomena of German PWR estimated from CCTF [Cylindrical Core Test Facility], SCTF [Slab Core Test Facility] and UPTF [Upper Plenum Test Facility] results

International Nuclear Information System (INIS)

Murao, Y.; Iguchi, T.; Sugimoto, J.

1988-09-01

The reflooding behavior in a PWR with a combined injection type ECCS was studied by comparing the test results from Cylindrical Core Test Facility (CCTF), Slab Core Test Facility (SCTF) and Upper Plenum Test Facility (UPTF). Core thermal-hydraulics is discussed mainly based on SCTF test data. In addition, the water accumulation behavior in hot legs and the break-through characteristics at tie plate are discussed

A microprocessor based monitoring system for a small nuclear reactor facility

International Nuclear Information System (INIS)

Miller, G.E.; DeKeyser, C.F.

1980-01-01

An inexpensive microprocessor based system has been designed and constructed for our 250 kilowatt TRIGA reactor facility. The system, which is beginning operational testing, can monitor on a continuous basis the status of up to 54 devices and maintain a record of events. These devices include fixed radiation monitors, pool water level trips, security alarms and an access control unit. In the latter case, the unit permits selection of different levels of access permission based on the time of day. The system can alert security and other personnel in the event of abnormalities. Because of the inclusion of this in the security system, special reliability and failure mode operation. The unit must also be simple to install, program and operate. (author)

Feasibility study for a biomedical experimental facility based on LEIR at CERN

International Nuclear Information System (INIS)

Abler, Daniel; Garonna, Adriano; Carli, Christian; Dosanjh, Manjit; Peach, Ken

2013-01-01

In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. This basic research would support the current clinical efforts of the new treatment centres in Europe (for example HIT, CNAO and MedAustron). This paper presents first investigations on the feasibility of an experimental biomedical facility based on the CERN Low Energy Ion Ring LEIR accelerator. Such a new facility could provide beams of light ions (from protons to neon ions) in a collaborative and cost-effective way, since it would rely partly on CERN's competences and infrastructure. The main technical challenges linked to the implementation of a slow extraction scheme for LEIR and to the design of the experimental beamlines are described and first solutions presented. These include introducing new extraction septa into one of the straight sections of the synchrotron, changing the power supply configuration of the magnets, and designing a new horizontal beamline suitable for clinical beam energies, and a low-energy vertical beamline for particular radiobiological experiments. (author)

Feasibility study for a biomedical experimental facility based on LEIR at CERN.

Science.gov (United States)

Abler, Daniel; Garonna, Adriano; Carli, Christian; Dosanjh, Manjit; Peach, Ken

2013-07-01

In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. This basic research would support the current clinical efforts of the new treatment centres in Europe (for example HIT, CNAO and MedAustron). This paper presents first investigations on the feasibility of an experimental biomedical facility based on the CERN Low Energy Ion Ring LEIR accelerator. Such a new facility could provide beams of light ions (from protons to neon ions) in a collaborative and cost-effective way, since it would rely partly on CERN's competences and infrastructure. The main technical challenges linked to the implementation of a slow extraction scheme for LEIR and to the design of the experimental beamlines are described and first solutions presented. These include introducing new extraction septa into one of the straight sections of the synchrotron, changing the power supply configuration of the magnets, and designing a new horizontal beamline suitable for clinical beam energies, and a low-energy vertical beamline for particular radiobiological experiments.

Family planning and reproductive health supply stockouts: problems and remedies for faith-based health facilities in Africa

Directory of Open Access Journals (Sweden)

Amy M. Metzger

2017-01-01

Full Text Available Background and aims: Faith-based organizations (FBOs provide a substantial portion of the health care services in many African countries. FBO facilities do consider family planning and reproductive health services as essential to reducing maternal and child mortality, and to the growth of healthy families. Many health facilities, however, struggle to maintain adequate stocks of reproductive health (RH supplies because of the various RH supply chains and funding sources, which often operate separately from other medicines and supplies. The purpose of this study is to identify the types of supply chain systems used by African faith-based health facilities to acquire reproductive health products (clotrimazole, combined oral contraceptive pills, contraceptive implants, CycleBeads®, emergency contraception, Erythromycin, female condoms, injectable contraceptives, intra-uterine contraceptive devices, magnesium sulfate, male condoms, Methyldopa, Misoprostol, Nifedpine, Oxytocin, and Progestin-only pills, to describe their problems and challenges, and to identify possible corrective actions. Methods: Through email surveys, phone interviews, and on-site visits, we studied the supply chains of 46 faith-based health facilities in 13 African countries. Sixteen RH commodities, including contraceptives, were selected as indicators. Results: Of the 46 facilities surveyed, 55 percent faced stockouts of one or more products in the three months prior to the survey. Stockouts were less common for contraceptives than for other RH products. Significant strengths of the FBO supply chain included creativity in finding other sources of commodities in the face of stockouts, staff designated to monitor quality of the commodities, high capacity for storage, low incidence of expired products, few instances of poor quality, and strong financial sustainability mechanisms, often including patient fees. Weaknesses included unreliable commodity sources and power supplies, long

Radiation protection programme for a radioisotope production facility

International Nuclear Information System (INIS)

Makgato, Thutu Nelson

2015-02-01

The present project reviews reactor based radioisotope production facilities. An overview of techniques and methodologies used as well as laboratory facilities necessary for the production process are discussed. Specific details of reactor based production and processing of more commonly used industrial and pharmaceutical radioisotopes are provided. Ultimately, based on facilities and techniques utilized as well as the associated hazard assessment, a proposed radiation protection programme is discussed. Elements of the radiation protection programme will also consider lessons from recent incidents and accidents encountered in radioisotope production facilities. (au)

THE DEVELOPMENT OF COAL-BASED TECHNOLOGIES FOR DEPARTMENT OF DEFENSE FACILITIES

Energy Technology Data Exchange (ETDEWEB)

Bruce G. Miller; Sharon Falcone Miller; Sarma V. Pisupati; Chunshan Song; Ronald S. Wasco; Ronald T. Wincek; Xiaochun Xu; Alan W. Scaroni; Richard Hogg; Subhash Chander; M. Thaddeus Ityokumbul; Mark S. Klima; Peter T. Luckie; Adam Rose; Richard L. Gordon; Jeffrey Lazo; A. Michael Schaal

2004-01-30

The third phase of a three-phase project investigating the development of coal-based technologies for US Department of Defense (DOD) facilities was completed. The objectives of the project were to: decrease DOD's dependence on foreign oil and increase its use of coal; promote public and private sector deployment of technologies for utilizing coal-based fuels in oil-designed combustion equipment; and provide a continuing environment for research and development of coal-based fuel technologies for small-scale applications at a time when market conditions in the US are not favorable for the introduction of coal-fired equipment in the commercial and industrial capacity ranges. The Phase III activities were focused on evaluating deeply-cleaned coals as fuels for industrial boilers and investigating emissions control strategies for providing ultra-low emissions when firing coal-based fuels. This was addressed by performing coal beneficiation and preparation studies, and bench- to demonstration-scale emissions reduction studies. In addition, economic studies were conducted focused on determining cost and market penetration, selection of incentives, and regional economic impacts of coal-based technologies.

A Remote WIRELESS Facility

Directory of Open Access Journals (Sweden)

Kees Uiterwijk

2007-10-01

Full Text Available Continuing need for available distance learning facilities has led to the development of a remote lab facility focusing on wireless technology. In the field of engineering there is a student need of gaining experience in set-up, monitoring and maintenance of 802.11A/B/G based wireless LAN environments.

The CUTLASS database facilities

International Nuclear Information System (INIS)

Jervis, P.; Rutter, P.

1988-09-01

The enhancement of the CUTLASS database management system to provide improved facilities for data handling is seen as a prerequisite to its effective use for future power station data processing and control applications. This particularly applies to the larger projects such as AGR data processing system refurbishments, and the data processing systems required for the new Coal Fired Reference Design stations. In anticipation of the need for improved data handling facilities in CUTLASS, the CEGB established a User Sub-Group in the early 1980's to define the database facilities required by users. Following the endorsement of the resulting specification and a detailed design study, the database facilities have been implemented as an integral part of the CUTLASS system. This paper provides an introduction to the range of CUTLASS Database facilities, and emphasises the role of Database as the central facility around which future Kit 1 and (particularly) Kit 6 CUTLASS based data processing and control systems will be designed and implemented. (author)

Supply-side barriers to maternity-care in India: a facility-based analysis.

Directory of Open Access Journals (Sweden)

Santosh Kumar

Full Text Available BACKGROUND: Health facilities in many low- and middle-income countries face several types of barriers in delivering quality health services. Availability of resources at the facility may significantly affect the volume and quality of services provided. This study investigates the effect of supply-side determinants of maternity-care provision in India. METHODS: Health facility data from the District-Level Household Survey collected in 2007-2008 were analyzed to explore the effects of supply-side factors on the volume of delivery care provided at Indian health facilities. A negative binomial regression model was applied to the data due to the count and over-dispersion property of the outcome variable (number of deliveries performed at the facility. RESULTS: Availability of a labor room (Incidence Rate Ratio [IRR]: 1.81; 95% Confidence Interval [CI]: 1.68-1.95 and facility opening hours (IRR: 1.43; CI: 1.35-1.51 were the most significant predictors of the volume of delivery care at the health facilities. Medical and paramedical staff were found to be positively associated with institutional deliveries. The volume of deliveries was also higher if adequate beds, essential obstetric drugs, medical equipment, electricity, and communication infrastructures were available at the facility. Findings were robust to the inclusion of facility's catchment area population and district-level education, health insurance coverage, religion, wealth, and fertility. Separate analyses were performed for facilities with and without a labor room and results were qualitatively similar across these two types of facilities. CONCLUSIONS: Our study highlights the importance of supply-side barriers to maternity-care India. To meet Millennium Development Goals 4 and 5, policymakers should make additional investments in improving the availability of medical drugs and equipment at primary health centers (PHCs in India.

Technical report on design base events related to the safety assessment of a Low-level Waste Storage Facility (LWSF)

International Nuclear Information System (INIS)

Karino, Motonobu; Uryu, Mitsuru; Miyata, Kazutoshi; Matsui, Norio; Imamoto, Nobuo; Kawamata, Tatsuo; Saito, Yasuo; Nagayama, Mineo; Wakui, Yasuyuki

1999-07-01

The construction of a new Low-level Waste Storage Facility (LWSF) is planned for storage of concentrated liquid waste from existing Low-level Radioactive Waste Treatment Facility in Tokai Reprocessing Plant of JNC. An essential base for the safety designing of the facility is correctly implemented the adoption of the defence in depth principle. This report summarized criteria for judgement, selection of postulated events, major analytical conditions for anticipated operational occurrences and accidents for the safety assessment and evaluation of each event were presented. (Itami, H.)

Liberia_WADC00004_OHDR_Health_Facilities2010

Data.gov (United States)

United Nations Cartographic Section — This data is based on the survey questionnaire, which are included in the table belowWhat county is this facility in?What is the facility name?Is this facility a...

Hazard Baseline Downgrade Effluent Treatment Facility

International Nuclear Information System (INIS)

Blanchard, A.

1998-01-01

This Hazard Baseline Downgrade reviews the Effluent Treatment Facility, in accordance with Department of Energy Order 5480.23, WSRC11Q Facility Safety Document Manual, DOE-STD-1027-92, and DOE-EM-STD-5502-94. It provides a baseline grouping based on the chemical and radiological hazards associated with the facility. The Determination of the baseline grouping for ETF will aid in establishing the appropriate set of standards for the facility

Towards a Strength-Based Juvenile Correctional Facility: Sustainability and Effects of an Institutional Transformation

Science.gov (United States)

Barton, William H.; Mackin, Juliette R.

2012-01-01

In 2006, the administration of a state-run, secure juvenile correctional facility initiated an attempt to transform its institutional culture using a strength-based approach to assessment and case planning. This resulted in a rapid improvement in institutional climate. The current study revisits this setting several years later to see if those…

A research-based profile of a Dutch excellent facility manager

NARCIS (Netherlands)

Roos-Mink, Anke; Offringa, Johan; de Boer, Esther; Heijne-Penninga, Marjolein; Mobach, Mark P.; Wolfensberger, Marca; Balslev Nielsen, S.; Anker Jensen, P.

2016-01-01

Purpose - This paper aims to establish the profile of an excellent facility manager in The Netherlands.Design/methodology/approach − As part of a large-scale study on profiles of excellent professionals, a study was carried out to find the key characteristics of an excellent facility manager. Three

Comprehensive facilities plan

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

The Ernest Orlando Lawrence Berkeley National Laboratory`s Comprehensive Facilities Plan (CFP) document provides analysis and policy guidance for the effective use and orderly future development of land and capital assets at the Berkeley Lab site. The CFP directly supports Berkeley Lab`s role as a multiprogram national laboratory operated by the University of California (UC) for the Department of Energy (DOE). The CFP is revised annually on Berkeley Lab`s Facilities Planning Website. Major revisions are consistent with DOE policy and review guidance. Facilities planing is motivated by the need to develop facilities for DOE programmatic needs; to maintain, replace and rehabilitate existing obsolete facilities; to identify sites for anticipated programmatic growth; and to establish a planning framework in recognition of site amenities and the surrounding community. The CFP presents a concise expression of the policy for the future physical development of the Laboratory, based upon anticipated operational needs of research programs and the environmental setting. It is a product of the ongoing planning processes and is a dynamic information source.

Overview of the applications of cement-based immobilization technologies developed at US DOE facilities

International Nuclear Information System (INIS)

Dole, L.R.

1985-01-01

This paper briefly reviews seven cement-based waste form development programs at six of the US Department of Energy (DOE) sites. These sites have developed a variety of processes that range from producing 25-mm-(1-in.-) diam pellets in a glove box to producing 240-m-(800-ft-) diam grout sheets within the bedding planes of a deep shale formation. These successful applications of cement-based waste forms to the many radioactive waste streams from nuclear facilities bear witness to the flexibility and reliability of this class of immobilization materials. The US DOE sites and their programs are: (1) Oak Ridge National Laboratory (ORNL), Hydrofracture Grout; (2) Hanford, Transportable Grout Facility (TGF); (3) Savannah River Plant (SRP), Nitrate Saltcrete; (4) EG and G Idaho, Process Experimental Pilot Plant (PREPP); (5) Mound Laboratory (ML), Waste Pelletization Process; (6) ORNL, FUETAP Concretes, and (7) Rocky Flats Plant (RFP), Inert Carrier Concrete Process (ICCP). The major issues regarding the application of cement-based waste forms to radioactive waste management problems are also presented. These issues are (1) leachability, (2) radiation stability, (3) thermal stability, (4) phase complexity of the matrix, and (5) effects of the waste stream composition. A cursory review of current research in each of these areas is included along with a discussion of future trends in cement-based waste form developments and applications. 35 refs., 12 figs

A conceptual design of neutron tumor therapy reactor facility with a YAYOI based fast neutron source reactor

International Nuclear Information System (INIS)

Wakabayashi, Hiroaki; An, Shigehiro.

1983-01-01

Fast neutron is known as one of useful radiations for radiation therapy of tumors. Boron neutron capture therapy (BNCT) of tumors which makes use of 10 B(n, α) 7 Li reaction of 10 B compounds selectively attached to tumor cells with thermal and intermediate neutrons is another way of neutron based radiation therapy which is, above all, attractive enough to kill tumor cells selectively sparing normal tissue. In Japan, BNCT has already been applied and leaned to be effective. After more than a decade operational experiences and the specific experiments designed for therapeutical purposes, in this paper, a conceptual design of a special neutron therapy reactor facility based on YAYOI - fast neutron source reactor of Nuclear Engineering Research Laboratory, Faculty of Engineering, the University of Tokyo - modified to provide an upward beam of fast and intermediate neutrons is presented. Emphasis is placed on the in-house nature of facility and on the coordinating capability of biological and physical researches as well as maintenances of the facility. (author)

Maternal death audit in Rwanda 2009-2013: a nationwide facility-based retrospective cohort study.

Science.gov (United States)

Sayinzoga, Felix; Bijlmakers, Leon; van Dillen, Jeroen; Mivumbi, Victor; Ngabo, Fidèle; van der Velden, Koos

2016-01-22

Presenting the results of 5 years of implementing health facility-based maternal death audits in Rwanda, showing maternal death classification, identification of substandard (care) factors that have contributed to death, and conclusive recommendations for quality improvements in maternal and obstetric care. Nationwide facility-based retrospective cohort study. All cases of maternal death audited by district hospital-based audit teams between January 2009 and December 2013 were reviewed. Maternal deaths that were not subjected to a local audit are not part of the cohort. 987 audited cases of maternal death. Characteristics of deceased women, timing of onset of complications, place of death, parity, gravida, antenatal clinic attendance, reported cause of death, service factors and individual factors identified by committees as having contributed to death, and recommendations made by audit teams. 987 cases were audited, representing 93.1% of all maternal deaths reported through the national health management information system over the 5-year period. Almost 3 quarters of the deaths (71.6%) occurred at district hospitals. In 44.9% of these cases, death occurred in the post-partum period. Seventy per cent were due to direct causes, with post-partum haemorrhage as the leading cause (22.7%), followed by obstructed labour (12.3%). Indirect causes accounted for 25.7% of maternal deaths, with malaria as the leading cause (7.5%). Health system failures were identified as the main responsible factor for the majority of cases (61.0%); in 30.3% of the cases, the main factor was patient or community related. The facility-based maternal death audit approach has helped hospital teams to identify direct and indirect causes of death, and their contributing factors, and to make recommendations for actions that would reduce the risk of reoccurrence. Rwanda can complement maternal death audits with other strategies, in particular confidential enquiries and near-miss audits, so as to

Understanding the relationship between access to care and facility-based delivery through analysis of the 2008 Ghana Demographic Health Survey.

Science.gov (United States)

Moyer, Cheryl A; McLaren, Zoë M; Adanu, Richard M; Lantz, Paula M

2013-09-01

To determine the types of access to care most strongly associated with facility-based delivery among women in Ghana. Data relating to the "5 As of Access" framework were extracted from the 2008 Ghana Demographic Health Survey and analyzed using multivariate logistic regression. In all, 55.5% of a weighted sample of 1102 women delivered in a healthcare facility, whereas 45.5% delivered at home. Affordability was the strongest access factor associated with delivery location, with health insurance coverage tripling the odds of facility delivery. Availability, accessibility (except urban residence), acceptability, and social access variables were not significant factors in the final models. Social access variables, including needing permission to seek healthcare and not being involved in decisions regarding healthcare, were associated with a reduced likelihood of facility-based delivery when examined individually. Multivariate analysis suggested that these variables reflected maternal literacy, health insurance coverage, and household wealth, all of which attenuated the effects of social access. Affordability was an important determinant of facility delivery in Ghana-even among women with health insurance-but social access variables had a mediating role. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Nuclear safety and radiation protection report of EdF's Tricastin operational hot base nuclear facilities (BCOT) - 2010

International Nuclear Information System (INIS)

2011-06-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the Tricastin operational hot base facility (INB no. 157, Bollene, Vaucluse (FR)), a nuclear workshop for storage and maintenance and qualification operations on some EdF equipments. Then, the nuclear safety and radiation protection measures taken regarding the facility are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, if some, are reported as well as the effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facility is presented and sorted by type of waste, quantities and type of conditioning. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

Polyurethane-acrylate-based hydrophobic film: Facile fabrication, characterization, and application

Science.gov (United States)

Park, Jongsung; Nguyen, Bui Quoc Huy; Kim, Ji-Kwan; Shanmugasundaram, Arunkumar; Lee, Dong-Weon

2018-06-01

Polyurethane-acrylate (PUA) is a versatile UV-curable polymer with a short curing time at room temperature, whose surface structure can be flexibly modified by applying various micropatterns. In this paper, we propose a facile and cost-effective fabrication method for the continuous production of an optically transparent PUA-based superhydrophobic thin film. Poly(dimethylsiloxane) (PDMS) was employed as a soft mold for the fabrication of PUA films through the roll-to-roll technique. In addition, nanosilica was spray-coated onto the PUA surface to further improve the hydrophobicity. The fabricated PUA thin film showed the highest static water contact angle (WCA) of ∼140°. The high durability of the PUA film was also demonstrated through mechanical impacting tests. Furthermore, only ∼2% of voltage loss was observed in the solar panel covered with the PUA-based superhydrophobic film. These obtained results indicate the feasibility of applying the film as a protective layer in applications requiring a high transparency and a self-cleaning effect.

Measurements of nuclear data and possibility to construct the nuclear data production facility based on electron linac

Energy Technology Data Exchange (ETDEWEB)

Namkung, Won; Ko, In Soo; Cho, Moo Hyun; Kim, Gui Nyun; Lee, Young Seok; Kang, Heung Sik [Pohang University of Science and Technology, Pohang(Korea)

2001-04-01

In order to construct an infrastructure to produce nuclear data, we studied three main items; (1) Study on the possibility to construct a facility for nuclear data production, (2) Production of nuclear data for nuclear power plant, and (3) Pulsed neutron source based on a 100-MeV electron linac at Pohang Accelerator Laboratory (PAL). We confirmed the possibility to build a nuclear data production facility utilizing a 100-MeV electron linac at PAL and manpower who wanted to participate the nuclear data production experiments. In order to measure the nuclear data for nuclear power plant, we used several nuclear data production facilities in abroad. We measured total cross sections and neutron caprure cross sections for {sup nat}Dy and {sup nat}Hf using the pulsed neutron facility in the Research Reactor Institute, Kyoto University (KURRI). The neutron capture cross sections for {sup 161,162,163,164}Dy were measured at KURRI in the neutron energy region between 0.001 eV and several tens keV, and at the fast neutron facility in Tokyo Institute of Technology in the neutron energy region between 10 keV and 100 keV. We also measured the neutron capture cross sections and gamma multiplicity of {sup 232}Th at the IBR30 in Dubna, Russia. We have construct a pulsed neutron source using a 100-MeV electron linac at PAL. We measured neutron time-of-flight (TOF) spectra in order to check the characteristics of the pulsed neutron source. We also measured a neutron total cross sections of W and Cu. The pulsed neutron facility can be utilized in the education facility for nuclear data production and the test facility for the R and D purpose of the nuclear data production facility. 29 refs., 57 figs., 22 tabs. (Author)

A Study of Scenic Spot Living Facility Recommendation Based on Collaborative Filtering

Directory of Open Access Journals (Sweden)

Luo Wenbiao

2015-01-01

Full Text Available For the collection of massive complex information, the collaborative filtering system can work as a highly efficient information screening tool. It can recommend reasonable information reserve with multi angles according to the living service facility information of the scenic spots. The collaborative filtering system can collect information and forecast rating results based on users’ preference. According to different recommendation goals, the collaborative filtering system can recommend results for user feedback and give feedback of the recommendation results in various forms.

Comparison of tritium production facilities

International Nuclear Information System (INIS)

He Kaihui; Huang Jinhua

2002-01-01

Detailed investigation and research on the source of tritium, tritium production facilities and their comparison are presented based on the basic information about tritium. The characteristics of three types of proposed tritium production facilities, i.e., fissile type, accelerator production tritium (APT) and fusion type, are presented. APT shows many advantages except its rather high cost; fusion reactors appear to offer improved safety and environmental impacts, in particular, tritium production based on the fusion-based neutron source costs much lower and directly helps the development of fusion energy source

A systematic review on barriers, facilities, knowledge and attitude toward evidence-based medicine in Iran

Directory of Open Access Journals (Sweden)

Morteza Ghojazadeh

2015-03-01

Full Text Available Introduction: Evidence-based medicine (EBM is the ability and skill in using and integration of the best up-to-date evidences. The aim of this study was a systematic review of barriers, facilities, knowledge and attitude of EBM in Iran. Methods: In this study, database and manual search was used with keywords such as, "evidence-based, EBM, evidence-based nursing, evidence-based practice, evidence-based care, evidence-based activities, evidence-based education" and their combination with the keywords of the barrier, facilitator, attitude, awareness, prospective, knowledge, practice and Iran. The databases of SID (Scientific information database, Magiran, MEDLIB, PubMed, Google scholar, IranMedex and CINAHL (Cumulative index to nursing and allied health literature were used for data collection. Results: Finally, 28 papers were included in this study. The lack of facilities, time and skill in research methodology were the most important barriers to EBM. The most and least important factors were orderly creating ample opportunity and detecting needs and problems. The degree of familiarity with the terminology of evidence-based performance was low (44.2%. The textbooks have been considered as the most significant source of obtaining information. The level of awareness, knowledge, and evidence-based performance was less than 50.0%. Conclusion: There are many various barriers in use of EBM and healthcare providers despite the positive attitude toward EBM had a low level knowledge in EBM setting. Consideration of the importance of EBM proper planning and effective intervention are necessary to removing the barriers and increase the knowledge of healthcare providers.

Needs of Advanced Safeguards Technologies for Future Nuclear Fuel Cycle (FNFC) Facilities and a Trial Application of SBD Concept to Facility Design of a Hypothetical FNFC Facility

International Nuclear Information System (INIS)

Seya, M.; Hajima, R.; Nishimori, N.; Hayakawa, T.; Kikuzawa, N.; Shizuma, T.; Fujiwara, M.

2010-01-01

Some of future nuclear fuel cycle (FNFC) facilities are supposed to have the characteristic features of very large throughput of plutonium, low decontamination reprocessing (no purification process; existence of certain amount of fission products (FP) in all process material), full minor actinides (MA) recycle, and treatment of MOX with FP and MA in fuel fabrication. In addition, the following international safeguards requirements have to be taken into account for safeguards approaches of the FNFC facilities. -Application of integrated safeguards (IS) approach; -Remote (unattended) verification; - 'Safeguards by Design' (SBD) concept. These features and requirements compel us to develop advanced technologies, which are not emerged yet. In order to realize the SBD, facility designers have to know important parts of design information on advanced safeguards systems before starting the facility design. The SBD concept requires not only early start of R and D of advanced safeguards technologies (before starting preliminary design of the facility) but also interaction steps between researchers working on safeguards systems and nuclear facility designers. The interaction steps are follows. Step-1; researchers show images of advanced safeguards systems to facility designers based on their research. Step-2; facility designers take important design information on safeguards systems into process systems of demonstration (or test) facility. Step-3; demonstration and improvement of both systems based on the conceptual design. Step-4; Construction of a FNFC facility with the advanced safeguards systems We present a trial application of the SBD concept to a hypothetical FNFC facility with an advanced hybrid K-edge densitometer and a Pu NDA system for spent nuclear fuel assembly using laser Compton scattering (LCS) X-rays and γ-rays and other advanced safeguards systems. (author)

Microcomputer simulation model for facility performance assessment: a case study of nuclear spent fuel handling facility operations

International Nuclear Information System (INIS)

Chockie, A.D.; Hostick, C.J.; Otis, P.T.

1985-10-01

A microcomputer based simulation model was recently developed at the Pacific Northwest Laboratory (PNL) to assist in the evaluation of design alternatives for a proposed facility to receive, consolidate and store nuclear spent fuel from US commercial power plants. Previous performance assessments were limited to deterministic calculations and Gantt chart representations of the facility operations. To insure that the design of the facility will be adequate to meet the specified throughput requirements, the simulation model was used to analyze such factors as material flow, equipment capability and the interface between the MRS facility and the nuclear waste transportation system. The simulation analysis model was based on commercially available software and application programs designed to represent the MRS waste handling facility operations. The results of the evaluation were used by the design review team at PNL to identify areas where design modifications should be considered. 4 figs

Design and control of LCL-filter with active damping for Active Power Filter

DEFF Research Database (Denmark)

Zeng, Guohong; Rasmussen, Tonny Wederberg; Ma, L

2010-01-01

of LCL-filter for APF is introduced, which is aimed for simplified the implementation. To suppress the resonance that may be excited in the system, which brings in stability problems, an active damping control strategy using the current feed-back of the filter capacitor is adopted. By selecting two equal......In the application of shunt Active Power Filter (APF) to compensate nonlinear load's harmonic, reactive and negative sequence current, it is more effective to use a LCL-filter than an L-filter as an interface between the Voltage Source Converter (VSC) and grid. In this paper, a designing procedure...... or similar inductances, the filter designing become more simple and effective, meanwhile the capacitance requirement is minimized. A pole-zero automatic cancellation phenomenon is discussed in this paper, which can be applied to simplify the current regulator designing. The tuning method is presented, based...

Refurbishment of JMTR pure water facility

International Nuclear Information System (INIS)

Asano, Norikazu; Hanakawa, Hiroki; Kusunoki, Hidehiko; Satou, Shinichi

2012-05-01

In the refurbishment of JMTR, facilities were classified into which (1) were all updated, (2) were partly updated, and (3) were continuance used by the considerations of the maintenance history, the change parts availability and the latest technology. The JMTR pure water facility was classified into all updated facility based on the consideration. The Update construction was conducted in between FY2007 and FY2008. The refurbishment of JMTR pure water facility is summarized in this report. (author)

Physician Beliefs and Practices for Adjuvant and Salvage Radiation Therapy After Prostatectomy

International Nuclear Information System (INIS)

Showalter, Timothy N.; Ohri, Nitin; Teti, Kristopher G.; Foley, Kathleen A.; Keith, Scott W.; Trabulsi, Edouard J.; Lallas, Costas D.; Dicker, Adam P.; Hoffman-Censits, Jean; Pizzi, Laura T.; Gomella, Leonard G.

2012-01-01

Purpose: Despite results of randomized trials that support adjuvant radiation therapy (RT) after radical prostatectomy (RP) for prostate cancer with adverse pathologic features (APF), many clinicians favor selective use of salvage RT. This survey was conducted to evaluate the beliefs and practices of radiation oncologists (RO) and urologists (U) regarding RT after RP. Methods and Materials: We designed a Web-based survey of post-RP RT beliefs and policies. Survey invitations were e-mailed to a list of 926 RO and 591 U. APF were defined as extracapsular extension, seminal vesicle invasion, or positive surgical margin. Differences between U and RO in adjuvant RT recommendations were evaluated by comparative statistics. Multivariate analyses were performed to evaluate factors predictive of adjuvant RT recommendation. Results: Analyzable surveys were completed by 218 RO and 92 U (overallresponse rate, 20%). Adjuvant RT was recommended based on APF by 68% of respondents (78% RO, 44% U, p <0.001). U were less likely than RO to agree that adjuvant RT improves survival and/or biochemical control (p < 0.0001). PSA thresholds for salvage RT were higher among U than RO (p < 0.001). Predicted rates of erectile dysfunction due to RT were higher among U than RO (p <0.001). On multivariate analysis, respondent specialty was the only predictor of adjuvant RT recommendations. Conclusions: U are less likely than RO to recommend adjuvant RT. Future research efforts should focus on defining the toxicities of post-RP RT and on identifying the subgroups of patients who will benefit from adjuvant vs. selective salvage RT.

Physician Beliefs and Practices for Adjuvant and Salvage Radiation Therapy After Prostatectomy

Energy Technology Data Exchange (ETDEWEB)

Showalter, Timothy N., E-mail: timothy.showalter@jeffersonhospital.org [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Ohri, Nitin; Teti, Kristopher G. [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Foley, Kathleen A. [Strategic Consulting, Thomson Reuters Healthcare, Cambridge, MA (United States); Keith, Scott W. [Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA (United States); Trabulsi, Edouard J.; Lallas, Costas D. [Department of Urology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Dicker, Adam P. [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Hoffman-Censits, Jean [Department of Medical Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Pizzi, Laura T. [School of Pharmacy, Thomas Jefferson University, Philadelphia, PA (United States); Gomella, Leonard G. [Department of Urology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States)

2012-02-01

Purpose: Despite results of randomized trials that support adjuvant radiation therapy (RT) after radical prostatectomy (RP) for prostate cancer with adverse pathologic features (APF), many clinicians favor selective use of salvage RT. This survey was conducted to evaluate the beliefs and practices of radiation oncologists (RO) and urologists (U) regarding RT after RP. Methods and Materials: We designed a Web-based survey of post-RP RT beliefs and policies. Survey invitations were e-mailed to a list of 926 RO and 591 U. APF were defined as extracapsular extension, seminal vesicle invasion, or positive surgical margin. Differences between U and RO in adjuvant RT recommendations were evaluated by comparative statistics. Multivariate analyses were performed to evaluate factors predictive of adjuvant RT recommendation. Results: Analyzable surveys were completed by 218 RO and 92 U (overallresponse rate, 20%). Adjuvant RT was recommended based on APF by 68% of respondents (78% RO, 44% U, p <0.001). U were less likely than RO to agree that adjuvant RT improves survival and/or biochemical control (p < 0.0001). PSA thresholds for salvage RT were higher among U than RO (p < 0.001). Predicted rates of erectile dysfunction due to RT were higher among U than RO (p <0.001). On multivariate analysis, respondent specialty was the only predictor of adjuvant RT recommendations. Conclusions: U are less likely than RO to recommend adjuvant RT. Future research efforts should focus on defining the toxicities of post-RP RT and on identifying the subgroups of patients who will benefit from adjuvant vs. selective salvage RT.

Prospects for high-power radioactive beam facilities worldwide

CERN Document Server

Nolen, Jerry A

2003-01-01

Advances in accelerators, targets, ion sources, and experimental instrumentation are making possible ever more powerful facilities for basic and applied research with short-lived radioactive isotopes. There are several current generation facilities, based on a variety of technologies, operating worldwide. These include, for example, those based on the in-flight method such as the recently upgraded National Superconducting Cyclotron Laboratory at Michigan State University, the facility at RIKEN in Japan, GANIL in Caen, France, and GSI in Darmstadt, Germany. Present facilities based on the Isotope-Separator On-Line method include, for example, the ISOLDE laboratory at CERN, HRIBF at Oak Ridge, and the new high-power facility ISAC at TRIUMF in Vancouver. Next-generation facilities include the Radioactive-Ion Factory upgrade of RIKEN to higher energy and intensity and the upgrade of ISAC to a higher energy secondary beam; both of these projects are in progress. A new project, LINAG, to upgrade the capabilities at...

Summary Report - Inspections of DoD Facilities and Military Housing and Audits of Base Operations and Support Services Contracts

Science.gov (United States)

2016-10-14

drinking water quality, radon, pest management, mold, and radiation. In addition, during the Japan and Korea inspections, we evaluated the management...Components responsible for facilities management conduct such analyses and use the results of these root cause analyses to improve facility management...water quality, radon, mold, pest infestation, lead-based paint, asbestos, and radiation) requirements. These inspections should be conducted by

A simulation-based robust biofuel facility location model for an integrated bio-energy logistics network

Directory of Open Access Journals (Sweden)

Jae-Dong Hong

2014-10-01

Full Text Available Purpose: The purpose of this paper is to propose a simulation-based robust biofuel facility location model for solving an integrated bio-energy logistics network (IBLN problem, where biomass yield is often uncertain or difficult to determine.Design/methodology/approach: The IBLN considered in this paper consists of four different facilities: farm or harvest site (HS, collection facility (CF, biorefinery (BR, and blending station (BS. Authors propose a mixed integer quadratic modeling approach to simultaneously determine the optimal CF and BR locations and corresponding biomass and bio-energy transportation plans. The authors randomly generate biomass yield of each HS and find the optimal locations of CFs and BRs for each generated biomass yield, and select the robust locations of CFs and BRs to show the effects of biomass yield uncertainty on the optimality of CF and BR locations. Case studies using data from the State of South Carolina in the United State are conducted to demonstrate the developed model’s capability to better handle the impact of uncertainty of biomass yield.Findings: The results illustrate that the robust location model for BRs and CFs works very well in terms of the total logistics costs. The proposed model would help decision-makers find the most robust locations for biorefineries and collection facilities, which usually require huge investments, and would assist potential investors in identifying the least cost or important facilities to invest in the biomass and bio-energy industry.Originality/value: An optimal biofuel facility location model is formulated for the case of deterministic biomass yield. To improve the robustness of the model for cases with probabilistic biomass yield, the model is evaluated by a simulation approach using case studies. The proposed model and robustness concept would be a very useful tool that helps potential biofuel investors minimize their investment risk.

Power Systems Development Facility

International Nuclear Information System (INIS)

1993-06-01

The objective of the PSDF would be to provide a modular facility which would support the development of advanced, pilot-scale, coal-based power systems and hot gas clean-up components. These pilot-scale components would be designed to be large enough so that the results can be related and projected to commercial systems. The facility would use a modular approach to enhance the flexibility and capability for testing; consequently, overall capital and operating costs when compared with stand-alone facilities would be reduced by sharing resources common to different modules. The facility would identify and resolve technical barrier, as well as-provide a structure for long-term testing and performance assessment. It is also intended that the facility would evaluate the operational and performance characteristics of the advanced power systems with both bituminous and subbituminous coals. Five technology-based experimental modules are proposed for the PSDF: (1) an advanced gasifier module, (2) a fuel cell test module, (3) a PFBC module, (4) a combustion gas turbine module, and (5) a module comprised of five hot gas cleanup particulate control devices. The final module, the PCD, would capture coal-derived ash and particles from both the PFBC and advanced gasifier gas streams to provide for overall particulate emission control, as well as to protect the combustion turbine and the fuel cell

Vulnerability assessment of chemical industry facilities in South Korea based on the chemical accident history

Science.gov (United States)

Heo, S.; Lee, W. K.; Jong-Ryeul, S.; Kim, M. I.

2016-12-01

The use of chemical compounds are keep increasing because of their use in manufacturing industry. Chemical accident is growing as the consequence of the chemical use increment. Devastating damages from chemical accidents are far enough to aware people's cautious about the risk of the chemical accident. In South Korea, Gumi Hydrofluoric acid leaking accident triggered the importance of risk management and emphasized the preventing the accident over the damage reducing process after the accident occurs. Gumi accident encouraged the government data base construction relate to the chemical accident. As the result of this effort Chemical Safety-Clearing-house (CSC) have started to record the chemical accident information and damages according to the Harmful Chemical Substance Control Act (HCSC). CSC provide details information about the chemical accidents from 2002 to present. The detail informations are including title of company, address, business type, accident dates, accident types, accident chemical compounds, human damages inside of the chemical industry facilities, human damage outside of the chemical industry facilities, financial damages inside of the chemical industry facilities, and financial damages outside of the chemical industry facilities, environmental damages and response to the chemical accident. Collected the chemical accident history of South Korea from 2002 to 2015 and provide the spatial information to the each accident records based on their address. With the spatial information, compute the data on ArcGIS for the spatial-temporal analysis. The spatial-temporal information of chemical accident is organized by the chemical accident types, damages, and damages on environment and conduct the spatial proximity with local community and environmental receptors. Find the chemical accident vulnerable area of South Korea from 2002 to 2015 and add the vulnerable area of total period to examine the historically vulnerable area from the chemical accident in

MicroArray Facility: a laboratory information management system with extended support for Nylon based technologies

Directory of Open Access Journals (Sweden)

Beaudoing Emmanuel

2006-09-01

Full Text Available Abstract Background High throughput gene expression profiling (GEP is becoming a routine technique in life science laboratories. With experimental designs that repeatedly span thousands of genes and hundreds of samples, relying on a dedicated database infrastructure is no longer an option. GEP technology is a fast moving target, with new approaches constantly broadening the field diversity. This technology heterogeneity, compounded by the informatics complexity of GEP databases, means that software developments have so far focused on mainstream techniques, leaving less typical yet established techniques such as Nylon microarrays at best partially supported. Results MAF (MicroArray Facility is the laboratory database system we have developed for managing the design, production and hybridization of spotted microarrays. Although it can support the widely used glass microarrays and oligo-chips, MAF was designed with the specific idiosyncrasies of Nylon based microarrays in mind. Notably single channel radioactive probes, microarray stripping and reuse, vector control hybridizations and spike-in controls are all natively supported by the software suite. MicroArray Facility is MIAME supportive and dynamically provides feedback on missing annotations to help users estimate effective MIAME compliance. Genomic data such as clone identifiers and gene symbols are also directly annotated by MAF software using standard public resources. The MAGE-ML data format is implemented for full data export. Journalized database operations (audit tracking, data anonymization, material traceability and user/project level confidentiality policies are also managed by MAF. Conclusion MicroArray Facility is a complete data management system for microarray producers and end-users. Particular care has been devoted to adequately model Nylon based microarrays. The MAF system, developed and implemented in both private and academic environments, has proved a robust solution for

Scaling laws between population and facility densities.

Science.gov (United States)

Um, Jaegon; Son, Seung-Woo; Lee, Sung-Ik; Jeong, Hawoong; Kim, Beom Jun

2009-08-25

When a new facility like a grocery store, a school, or a fire station is planned, its location should ideally be determined by the necessities of people who live nearby. Empirically, it has been found that there exists a positive correlation between facility and population densities. In the present work, we investigate the ideal relation between the population and the facility densities within the framework of an economic mechanism governing microdynamics. In previous studies based on the global optimization of facility positions in minimizing the overall travel distance between people and facilities, it was shown that the density of facility D and that of population rho should follow a simple power law D approximately rho(2/3). In our empirical analysis, on the other hand, the power-law exponent alpha in D approximately rho(alpha) is not a fixed value but spreads in a broad range depending on facility types. To explain this discrepancy in alpha, we propose a model based on economic mechanisms that mimic the competitive balance between the profit of the facilities and the social opportunity cost for populations. Through our simple, microscopically driven model, we show that commercial facilities driven by the profit of the facilities have alpha = 1, whereas public facilities driven by the social opportunity cost have alpha = 2/3. We simulate this model to find the optimal positions of facilities on a real U.S. map and show that the results are consistent with the empirical data.

[Surveying a zoological facility through satellite-based geodesy].

Science.gov (United States)

Böer, M; Thien, W; Tölke, D

2000-06-01

In the course of a thesis submitted for a diploma degree within the Fachhochschule Oldenburg the Serengeti Safaripark was surveyed in autumn and winter 1996/97 laying in the planning foundations for the application for licences from the controlling authorities. Taking into consideration the special way of keeping animals in the Serengeti Safaripark (game ranching, spacious walk-through-facilities) the intention was to employ the outstanding satellite based geodesy. This technology relies on special aerials receiving signals from 24 satellites which circle around the globe. These data are being gathered and examined. This examination produces the exact position of this aerial in a system of coordinates which allows depicting this point on a map. This procedure was used stationary (from a strictly defined point) as well as in the movement (in a moving car). Additionally conventional procedures were used when the satellite based geodesy came to its limits. Finally a detailed map of the Serengeti Safaripark was created which shows the position and size of stables and enclosures as well as wood and water areas and the sectors of the leisure park. Furthermore the established areas of the enclosures together with an already existing animal databank have flown into an information system with the help of which the stock of animals can be managed enclosure-orientated.

Facility Interface Capability Assessment (FICA) project report

International Nuclear Information System (INIS)

Pope, R.B.; MacDonald, R.R.; Viebrock, J.M.; Mote, N.

1995-09-01

The US Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM) is responsible for developing the Civilian Radioactive Waste Management System (CRWMS) to accept spent nuclear fuel from commercial facilities. The objective of the Facility Interface Capability Assessment (FICA) project was to assess the capability of each commercial spent nuclear fuel (SNF) storage facility, at which SNF is stored, to handle various SNF shipping casks. The purpose of this report is to present and analyze the results of the facility assessments completed within the FICA project. During Phase 1, the data items required to complete the facility assessments were identified and the database for the project was created. During Phase 2, visits were made to 122 facilities on 76 sites to collect data and information, the database was updated, and assessments of the cask-handling capabilities at each facility were performed. Each assessment of cask-handling capability contains three parts: the current capability of the facility (planning base); the potential enhanced capability if revisions were made to the facility licensing and/or administrative controls; and the potential enhanced capability if limited physical modifications were made to the facility. The main conclusion derived from the planning base assessments is that the current facility capabilities will not allow handling of any of the FICA Casks at 49 of the 122 facilities evaluated. However, consideration of potential revisions and/or modifications showed that all but one of the 49 facilities could be adapted to handle at least one of the FICA Casks. For this to be possible, facility licensing, administrative controls, and/or physical aspects of the facility would need to be modified

Facility Interface Capability Assessment (FICA) project report

Energy Technology Data Exchange (ETDEWEB)

Pope, R.B. [ed.] [Oak Ridge National Lab., TN (United States); MacDonald, R.R. [ed.] [Civilian Radioactive Waste Management System, Vienna, VA (United States); Viebrock, J.M.; Mote, N. [Nuclear Assurance Corp., Norcross, GA (United States)

1995-09-01

The US Department of Energy`s (DOE) Office of Civilian Radioactive Waste Management (OCRWM) is responsible for developing the Civilian Radioactive Waste Management System (CRWMS) to accept spent nuclear fuel from commercial facilities. The objective of the Facility Interface Capability Assessment (FICA) project was to assess the capability of each commercial spent nuclear fuel (SNF) storage facility, at which SNF is stored, to handle various SNF shipping casks. The purpose of this report is to present and analyze the results of the facility assessments completed within the FICA project. During Phase 1, the data items required to complete the facility assessments were identified and the database for the project was created. During Phase 2, visits were made to 122 facilities on 76 sites to collect data and information, the database was updated, and assessments of the cask-handling capabilities at each facility were performed. Each assessment of cask-handling capability contains three parts: the current capability of the facility (planning base); the potential enhanced capability if revisions were made to the facility licensing and/or administrative controls; and the potential enhanced capability if limited physical modifications were made to the facility. The main conclusion derived from the planning base assessments is that the current facility capabilities will not allow handling of any of the FICA Casks at 49 of the 122 facilities evaluated. However, consideration of potential revisions and/or modifications showed that all but one of the 49 facilities could be adapted to handle at least one of the FICA Casks. For this to be possible, facility licensing, administrative controls, and/or physical aspects of the facility would need to be modified.

CO2 laser irradiation enhances CaF2 formation and inhibits lesion progression on demineralized dental enamel-in vitro study.

Science.gov (United States)

Zancopé, Bruna R; Rodrigues, Lívia P; Parisotto, Thais M; Steiner-Oliveira, Carolina; Rodrigues, Lidiany K A; Nobre-dos-Santos, Marinês

2016-04-01

This study evaluated if Carbon dioxide (CO2) (λ 10.6 μm) laser irradiation combined with acidulated phosphate fluoride gel application (APF gel) enhances "CaF2" uptake by demineralized enamel specimens (DES) and inhibits enamel lesion progression. Thus, two studies were conducted and DES were subjected to APF gel combined or not with CO2 laser irradiation (11.3 or 20.0 J/cm(2), 0.4 or 0.7 W) performed before, during, or after APF gel application. In study 1, 165 DES were allocated to 11 groups. Fluoride as "CaF2 like material" formed on enamel was determined in 100 DES (n = 10/group), and the surface morphologies of 50 specimens were evaluated by scanning electron microscopy (SEM) before and after "CaF2" extraction. In study 2, 165 DES (11 groups, n = 15), subjected to the same treatments as in study 1, were further subjected to a pH-cycling model to simulate a high cariogenic challenge. The progression of demineralization in DES was evaluated by cross-sectional microhardness and polarized light microscopy analyses. Laser at 11.3 J/cm(2) applied during APF gel application increased "CaF2" uptake on enamel surface. Laser irradiation and APF gel alone arrested the lesion progression compared with the control (p enamel surface and a synergistic effect was found. However, regarding the inhibition of caries lesion progression, no synergistic effect could be demonstrated. In conclusion, the results have shown that irradiation with specific laser parameters significantly enhanced CaF2 uptake by demineralized enamel and inhibited lesion progression.

Abscesso piogênico do fígado e esquistossomose mansônica: observações no Estado do Espírito Santo

Directory of Open Access Journals (Sweden)

Carlos Musso

1996-08-01

Full Text Available Recentemente, foi demonstrado que a forma toxêmica da esquistossomose mansônica em crianças pode serfator predisponente para abscesso piogênico do fígado (APF. Como no Estado do Espírito Santo, a esquistossomose é endêmica em grande parte do estado e os APF são freqüentemente diagnosticados no Hospital Infantil Nossa Senhora da Glória de Vitória, realizou-se revisão dos casos de APF diagnosticados entre maio de 1991 e abril de 1994, com a finalidade de identificar-se os casos com infecção esquistossomótica e a sua procedêitcia. Identificaram-se 65 casos de APF e 39 apresentavam exame de fezes registrado no prontuário, sendo 3 positivos para Schistosoma mansoni e 29 positivos para outros helmintos intestinais, principalmente áscaris e tricocéfalo. A procedência dos pacientes mostrou que 7 (10,6% eram provenientes de zona endêmica da esquistossomose. A associação APF e esquistossomose mostrou-se pequena e não há grande sobreposição na distribuição geográfica das duas doenças. Por outro lado a alta prevalência de infecção por outros helmintos intestinais e o grande número de abscessos piogênicos criptogenéticos diagnosticados, faz pensar que as infecções helmínticas com larvas que podem migrar para o fígado e formar granulomas, possam também ser um fator predisponente para o abscesso hepático em crianças.

Congenital arterioportal fistulas: radiological treatment and color Doppler US follow-up

Energy Technology Data Exchange (ETDEWEB)

Teplisky, Dario; Tincani, Eliana Uruena; Lipsich, Jose; Sierre, Sergio [Department of Interventional Radiology, Pichincha 1890, Buenos Aires (Argentina)

2012-11-15

Congenital intrahepatic arterioportal fistulas (APFs) are a rare cause of portal hypertension in children. Doppler US is a useful diagnostic imaging modality. Transarterial embolization is a minimally invasive and effective therapy allowing occlusion of the fistula and restoration of liver hemodynamics. To describe the clinical and radiologic findings, percutaneous treatment and role of D-US in the postembolization follow-up of children with APF. Between 2002 and 2011, four children with APF were treated. Initial diagnosis and follow-up was performed with D-US and confirmed by arteriography, followed by endovascular embolization in all patients. D-US demonstrated abnormal arterioportal communications in all patients. Six endovascular procedures were performed in these four children. In two children, no residual fistula was seen on D-US after the first procedure and symptoms resolved. In the other two children, D-US demonstrated residual flow through the fistula, with resolution of pathological D-US findings and symptoms after the second endovascular procedure. All four children were successfully treated and asymptomatic at the end of follow-up. The mean follow-up was 24 months. Interventional radiology has a key role in the treatment of congenital APF. D-US is a noninvasive and effective tool for the diagnosis and follow-up of these patients. (orig.)

Study on Soft Phase Locked Method to Solving the Synchronization Problem of Active Power Filter in Stand-alone Power Grid

DEFF Research Database (Denmark)

Zhuo, Fang; Wu, Longhui; Chen, Zhe

2009-01-01

on zero-cross detection can't work effectively in small rating stand-alone power grid. Then a soft phase locked loop with additional filter is proposed. It can lock the phase angle on to the positive sequence of fundamental voltage accurately and rapidly. It ensures the performance of APF applied...... in the small rating stand-alone power grid. Moreover, the soft phase locked loop is easy to be implemented in a Digital Signal Processor (DSP). Simulation and experimental results validate that the soft phase locked loop has satisfactory performance.......Traditional LC filters can't work stably in small rating stand-alone power grid. So active power filter (APF) is becoming an important tool to solve the power quality problem in small rating stand-alone power grid. In most current detection algorithm of APF, it needs a synchronizing signal. Firstly...

Preliminary studi on neutronic aspect of a conceptual design of the Kartini reactor base ADS facility

International Nuclear Information System (INIS)

Tegas Sutondo

2012-01-01

A preliminary study on neutronic aspect of a conceptual design of ADS facility with the basis of Kartini Reaktor, has been performed. The study was intended to see the feasibility from neutronic point of view of Kartini reactor, to be used as a small scale of NPP’s waste transmutation experimental facility. A SRAC code was used as the basis of calculations. The results indicate that the presence of minor actinides (MA) will give a positive reactivity, which tends to increase with the increase of MA concentrations. Based on the defined criteria of subcriticality and by considering the core power distributions and the level of reactivity contribution of MA element, it is concluded that Kartini reactor is potential enough to be used as an ADS experimental facility, mainly for MA concentration between 30 to 50 % of the assumed mixture of C-MA matrix. (author)

PROOF as a service on the cloud: a virtual analysis facility based on the CernVM ecosystem

International Nuclear Information System (INIS)

Berzano, D; Blomer, J; Buncic, P; Charalampidis, I; Ganis, G; Lestaris, G; Meusel, R

2014-01-01

PROOF, the Parallel ROOT Facility, is a ROOT-based framework which enables interactive parallelism for event-based tasks on a cluster of computing nodes. Although PROOF can be used simply from within a ROOT session with no additional requirements, deploying and configuring a PROOF cluster used to be not as straightforward. Recently great efforts have been spent to make the provisioning of generic PROOF analysis facilities with zero configuration, with the added advantages of positively affecting both stability and scalability, making the deployment operations feasible even for the end user. Since a growing amount of large-scale computing resources are nowadays made available by Cloud providers in a virtualized form, we have developed the Virtual PROOF-based Analysis Facility: a cluster appliance combining the solid CernVM ecosystem and PoD (PROOF on Demand), ready to be deployed on the Cloud and leveraging some peculiar Cloud features such as elasticity. We will show how this approach is effective both for sysadmins, who will have little or no configuration to do to run it on their Clouds, and for the end users, who are ultimately in full control of their PROOF cluster and can even easily restart it by themselves in the unfortunate event of a major failure. We will also show how elasticity leads to a more optimal and uniform usage of Cloud resources.

Designation of facility usage categories for Hanford Site facilities

International Nuclear Information System (INIS)

Wodrich, D.; Ellingson, D.; Scott, M.; Schade, A.

1991-01-01

This report summarizes the Hanford Site methodology used to ensure facility compliance with the natural phenomena design criteria set forth in the US Department of Energy orders and guidance. In particular, the Hanford Site approach to designating a suitable facility open-quotes Usage Category,close quotes is presented. The current Hanford Site methodology for Usage Category designation is based on an engineered feature's safety function and on the feature's assigned Safety Class. At the Hanford Site, Safety Class assignments are deterministic in nature and are based on the consequences of failure, without regard to the likelihood of occurrence. The report also proposes a risk-based approach to Usage Category designation, which is being considered for future application at the Hanford Site. To establish a proper Usage Category designation, the safety analysis and engineering design processes must be coupled. This union produces a common understanding of the safety function(s) to be accomplished by the design feature(s) and a sound basis for the assignment of Usage Categories to the appropriate systems, structures, and components

Development of a Tandem-Electrostatic-Quadrupole facility for Accelerator-Based Boron Neutron Capture Therapy

International Nuclear Information System (INIS)

Kreiner, A.J.; Castell, W.; Di Paolo, H.; Baldo, M.; Bergueiro, J.

2011-01-01

We describe the present status of an ongoing project to develop a Tandem-ElectroStatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based (AB)-BNCT. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the 7 Li(p,n) 7 Be reaction. The machine currently being constructed is a folded TESQ with a high-voltage terminal at 0.6 MV. We report here on the progress achieved in a number of different areas.

Disposal facility data for the interim performance

International Nuclear Information System (INIS)

Eiholzer, C.R.

1995-01-01

The purpose of this report is to identify and provide information on the waste package and disposal facility concepts to be used for the low-level waste tank interim performance assessment. Current concepts for the low-level waste form, canister, and the disposal facility will be used for the interim performance assessment. The concept for the waste form consists of vitrified glass cullet in a sulfur polymer cement matrix material. The waste form will be contained in a 2 x 2 x 8 meter carbon steel container. Two disposal facility concepts will be used for the interim performance assessment. These facility concepts are based on a preliminary disposal facility concept developed for estimating costs for a disposal options configuration study. These disposal concepts are based on vault type structures. None of the concepts given in this report have been approved by a Tank Waste Remediation Systems (TWRS) decision board. These concepts will only be used in th interim performance assessment. Future performance assessments will be based on approved designs

Expanding the suite of measures of gender-based discrimination: gender differences in ablution facilities in South Africa

Directory of Open Access Journals (Sweden)

Renier Steyn

2012-06-01

Full Text Available International treaties, national legislation and local by-laws all advocate the equal treatment of men and women, but claims of gender-based discrimination continue. Indicators of discrimination against women, including employment ratios and differences in income, show that there have been considerable gains in the recent past. These measures are, however, often biased. In this study a different, specific and concrete method of describing and detecting discrimination is presented, namely the difference in the number of ablution facilities provided for each gender group in public spaces. Ablution facilities at airports, train stations and shopping centres in four major South African cities (N=128 were inspected. Medium to large differences in the respective number of facilities were found (eta2 .05 to .13, with women receiving fewer service facilities than men. These results suggest that, despite progressive legislation and vigorous affirmative action in South Africa, local women are still being discriminated against on a very concrete, visible level. The effectiveness of the measurement tool is also discussed.

Decommissioning high-level waste surface facilities

International Nuclear Information System (INIS)

1978-04-01

The protective storage, entombment and dismantlement options of decommissioning a High-Level Waste Surface Facility (HLWSF) was investigated. A reference conceptual design for the facility was developed based on the designs of similar facilities. State-of-the-art decommissioning technologies were identified. Program plans and cost estimates for decommissioning the reference conceptual designs were developed. Good engineering design concepts were on the basis of this work identified

Robotics Research Facility

Data.gov (United States)

Federal Laboratory Consortium — This 60 feet x 100 feet structure on the grounds of the Fort Indiantown Gap Pennsylvania National Guard (PNG) Base is a mixed-use facility comprising office space,...

Accident Management ampersand Risk-Based Compliance With 40 CFR 68 for Chemical Process Facilities

International Nuclear Information System (INIS)

O'Kula, K.R.; Taylor, R.P. Jr.; Ashbaugh, S.G.

1995-01-01

A risk-based logic model is suggested as an appropriate basis for better predicting accident progression and ensuing source terms to the environment from process upset conditions in complex chemical process facilities. Under emergency conditions, decision-makers may use the Accident Progression Event Tree approach to identify the best countermeasure for minimizing deleterious consequences to receptor groups before the atmospheric release has initiated. It is concluded that the chemical process industry may use this methodology as a supplemental information provider to better comply with the Environmental Protection Agency's proposed 40 CFR 68 Risk Management Program rule. An illustration using a benzene-nitric acid potential interaction demonstrates the value of the logic process. The identification of worst-case releases and planning for emergency response are improved through these methods, at minimum. It also provides a systematic basis for prioritizing facility modifications to correct vulnerabilities

Analysis on the Present Status of Conceptually Designed Pyroprocessing Facilities for Determining a Reference Pyroprocessing Facility

International Nuclear Information System (INIS)

Shin, Hee Sung; Ahn, Seong Kyu; Song, Dae Yong; Lee, Tae Hoon; Kim, Ho Dong; Seo, Ji Sun; Im, Hye In; Jang, Je Nam

2009-12-01

In this report, pyro processing facility concepts suggested by US, Japan, and Republic of Korea have been summarized and analyzed, and the determination principles were established to determine a reference pyro processing facility concept. Three proposals for a reference pyro processing facility concept were suggested based on these principles. The 1st proposal is based on the GEN-IV PR/PP model except the metal fuel fabrication process. It may be possible to later add the metal fuel fabrication process, UO2 recovery process of Japan, and continuous electrorefining process invented in Republic of Korea to be the generic model including all pyroprocessing facility concepts in the world. The 2nd proposal is based on INL and ANL model which is simple for the most part and has basic essential processes. The 3rd proposal is determined to be the ESPF of KAERI, which is almost identical with that of the 2nd proposal except in regards to utilization of an input accountability tank and continuous electrorefining process and the 3rd proposal is planned to be realized in 7 years. After the review of the IAEA and discussions at 3rd Working Group Meeting held in IAEA headquarters, the 3rd proposal has been determined as the final version of a reference pyroprocessing facility concept

Cryogenic Fluid Management Facility

Science.gov (United States)

Eberhardt, R. N.; Bailey, W. J.

1985-01-01

The Cryogenic Fluid Management Facility is a reusable test bed which is designed to be carried within the Shuttle cargo bay to investigate the systems and technologies associated with the efficient management of cryogens in space. Cryogenic fluid management consists of the systems and technologies for: (1) liquid storage and supply, including capillary acquisition/expulsion systems which provide single-phase liquid to the user system, (2) both passive and active thermal control systems, and (3) fluid transfer/resupply systems, including transfer lines and receiver tanks. The facility contains a storage and supply tank, a transfer line and a receiver tank, configured to provide low-g verification of fluid and thermal models of cryogenic storage and transfer processes. The facility will provide design data and criteria for future subcritical cryogenic storage and transfer system applications, such as Space Station life support, attitude control, power and fuel depot supply, resupply tankers, external tank (ET) propellant scavenging, and ground-based and space-based orbit transfer vehicles (OTV).

Technical and economic assessment for asbestos abatement within Facility 20470, Wright-Patterson Air Force Base, Ohio

International Nuclear Information System (INIS)

Gibson, S.M.; Ogle, R.B.

1988-03-01

This report presents the results of a technical and economic assessment of available alternatives for asbestos abatement within Facility 20470 at the Wright-Patterson Air Force Base in Dayton, Ohio. Each alternative was screened on the basis of technical feasibility, environmental impact, economics, and fulfillment of the IRP goals. Four alternatives for study are: establishing a special operations and maintenance program; enclosure; encapsulation with sealants; and removal, disposal, and replacement. Each of these alternatives was assessed for capability to control the release of asbestos fibers within Facility 20470. Alternatives 1 and 4 were determined to be acceptable, while Alternatives 2 and 3 were found to be unacceptable. 2 refs., 6 figs

Radioactive facilities classification criteria

International Nuclear Information System (INIS)

Briso C, H.A.; Riesle W, J.

1992-01-01

Appropriate classification of radioactive facilities into groups of comparable risk constitutes one of the problems faced by most Regulatory Bodies. Regarding the radiological risk, the main facts to be considered are the radioactive inventory and the processes to which these radionuclides are subjected. Normally, operations are ruled by strict safety procedures. Thus, the total activity of the radionuclides existing in a given facility is the varying feature that defines its risk. In order to rely on a quantitative criterion and, considering that the Annual Limits of Intake are widely accepted references, an index based on these limits, to support decisions related to radioactive facilities, is proposed. (author)

Outline of NUCEF facility

International Nuclear Information System (INIS)

Takeshita, Isao

1996-01-01

NUCEF is a multipurpose research facility in the field of safety and advanced technology of nuclear fuel cycle back-end. Various experiment facilities and its supporting installations, in which nuclear fuel materials, radio isotopes and TRU elements can be handled, are arranged in more than one hundred rooms of two experiment buildings. Its construction was completed in middle of 1994 and hot experiments have been started since then. NUCEF is located on the site (30,000 m 2 ) of southeastern part in the Tokai Research Establishment of JAERI facing to the Pacific Ocean. The base of Experiment Buildings A and B was directly founded on the rock existing at 10-15 m below ground level taking the aseismatic design into consideration. Each building is almost same sized and composed of one basement and three floors of which area is 17,500 m 2 in total. In the basement, there are exhaust facilities of ventilation system, treatment system of solution fuel and radioactive waste solution and storage tanks of them. Major experiment facilities are located on the first or the second floors in each building. An air-inlet facility of ventilation system for each building is equipped on the third floor. Most of experiment facilities for criticality safety research including two critical facilities: Static Experiment Critical Facility (STACY) and Transient Experiment Critical Facility (TRACY) are installed in Experiment Building A. Experiment equipments for research on advanced fuel reprocessing process and on TRU waste management, which are named BECKY (Back End Fuel Cycle Key Elements Research Facility), are installed in laboratories and a-g cells in Experiment Building B. (J.P.N.)

Operating procedures: Fusion Experiments Analysis Facility

Energy Technology Data Exchange (ETDEWEB)

Lerche, R.A.; Carey, R.W.

1984-03-20

The Fusion Experiments Analysis Facility (FEAF) is a computer facility based on a DEC VAX 11/780 computer. It became operational in late 1982. At that time two manuals were written to aid users and staff in their interactions with the facility. This manual is designed as a reference to assist the FEAF staff in carrying out their responsibilities. It is meant to supplement equipment and software manuals supplied by the vendors. Also this manual provides the FEAF staff with a set of consistent, written guidelines for the daily operation of the facility.

Operating procedures: Fusion Experiments Analysis Facility

International Nuclear Information System (INIS)

Lerche, R.A.; Carey, R.W.

1984-01-01

The Fusion Experiments Analysis Facility (FEAF) is a computer facility based on a DEC VAX 11/780 computer. It became operational in late 1982. At that time two manuals were written to aid users and staff in their interactions with the facility. This manual is designed as a reference to assist the FEAF staff in carrying out their responsibilities. It is meant to supplement equipment and software manuals supplied by the vendors. Also this manual provides the FEAF staff with a set of consistent, written guidelines for the daily operation of the facility

Facile one-pot synthesis of porphyrin based porous polymer networks (PPNs) as biomimetic catalysts

Energy Technology Data Exchange (ETDEWEB)

Zou, LF; Feng, DW; Liu, TF; Chen, YP; Fordham, S; Yuan, S; Tian, J; Zhou, HC

2015-01-01

Stable porphyrin based porous polymer networks, PPN-23 and PPN-24, have been synthesized through a facile one-pot approach by the aromatic substitution reactions of pyrrole and aldehydes. PPN-24(Fe) shows high catalytic efficiency as a biomimetic catalyst in the oxidation reaction of 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) in the presence of H2O2.

The three waves in implementation of facility-based kangaroo mother care: a multi-country case study from Asia.

Science.gov (United States)

Bergh, Anne-Marie; de Graft-Johnson, Joseph; Khadka, Neena; Om'Iniabohs, Alyssa; Udani, Rekha; Pratomo, Hadi; De Leon-Mendoza, Socorro

2016-01-27

Kangaroo mother care has been highlighted as an effective intervention package to address high neonatal mortality pertaining to preterm births and low birth weight. However, KMC uptake and service coverage have not progressed well in many countries. The aim of this case study was to understand the institutionalisation processes of facility-based KMC services in three Asian countries (India, Indonesia and the Philippines) and the reasons for the slow uptake of KMC in these countries. Three main data sources were available: background documents providing insight in the state of implementation of KMC in the three countries; visits to a selection of health facilities to gauge their progress with KMC implementation; and data from interviews and meetings with key stakeholders. The establishment of KMC services at individual facilities began many years before official prioritisation for scale-up. Three major themes were identified: pioneers of facility-based KMC; patterns of KMC knowledge and skills dissemination; and uptake and expansion of KMC services in relation to global trends and national policies. Pioneers of facility-based KMC were introduced to the concept in the 1990s and established the practice in a few individual tertiary or teaching hospitals, without further spread. A training method beneficial to the initial establishment of KMC services in a country was to send institutional health-professional teams to learn abroad, notably in Colombia. Further in-country cascading took place afterwards and still later on KMC was integrated into newborn and obstetric care programs. The patchy uptake and expansion of KMC services took place in three phases aligned with global trends of the time: the pioneer phase with individual champions while the global focus was on child survival (1998-2006); the newborn-care phase (2007-2012); and lastly the current phase where small babies are also included in action plans. This paper illustrates the complexities of implementing a

Savannah River Site human error data base development for nonreactor nuclear facilities

International Nuclear Information System (INIS)

Benhardt, H.C.; Held, J.E.; Olsen, L.M.; Vail, R.E.; Eide, S.A.

1994-01-01

As part of an overall effort to upgrade and streamline methodologies for safety analyses of nonreactor nuclear facilities at the Savannah River Site (SRS), a human error data base has been developed and is presented in this report. The data base fulfills several needs of risk analysts supporting safety analysis report (SAR) development. First, it provides a single source for probabilities or rates for a wide variety of human errors associated with the SRS nonreactor nuclear facilities. Second, it provides a documented basis for human error probabilities or rates. And finally, it provides actual SRS-specific human error data to support many of the error probabilities or rates. Use of a single, documented reference source for human errors, supported by SRS-specific human error data, will improve the consistency and accuracy of human error modeling by SRS risk analysts. It is envisioned that SRS risk analysts will use this report as both a guide to identifying the types of human errors that may need to be included in risk models such as fault and event trees, and as a source for human error probabilities or rates. For each human error in this report, ffime different mean probabilities or rates are presented to cover a wide range of conditions and influencing factors. The ask analysts must decide which mean value is most appropriate for each particular application. If other types of human errors are needed for the risk models, the analyst must use other sources. Finally, if human enors are dominant in the quantified risk models (based on the values obtained fmm this report), then it may be appropriate to perform detailed human reliability analyses (HRAS) for the dominant events. This document does not provide guidance for such refined HRAS; in such cases experienced human reliability analysts should be involved

Computing facility at SSC for detectors

International Nuclear Information System (INIS)

Leibold, P.; Scipiono, B.

1990-01-01

A description of the RISC-based distributed computing facility for detector simulaiton being developed at the SSC Laboratory is discussed. The first phase of this facility is scheduled for completion in early 1991. Included is the status of the project, overview of the concepts used to model and define system architecture, networking capabilities for user access, plans for support of physics codes and related topics concerning the implementation of this facility

Use of a Balanced Scorecard in strengthening health systems in developing countries: an analysis based on nationally representative Bangladesh Health Facility Survey.

Science.gov (United States)

Khan, M Mahmud; Hotchkiss, David R; Dmytraczenko, Tania; Zunaid Ahsan, Karar

2013-01-01

This paper illustrates the importance of collecting facility-based data through regular surveys to supplement the administrative data, especially for developing countries of the world. In Bangladesh, measures based on facility survey indicate that only 70% of very basic medical instruments and 35% of essential drugs were available in health facilities. Less than 2% of officially designated obstetric care facilities actually had required drugs, injections and personnel on-site. Majority of (80%) referral hospitals at the district level were not ready to provide comprehensive emergency obstetric care. Even though the Management Information System reports availability of diagnostic machines in all district-level and sub-district-level facilities, it fails to indicate that 50% of these machines are not functional. In terms of human resources, both physicians and nurses are in short supply at all levels of the healthcare system. The physician-nurse ratio also remains lower than the desirable level of 3.0. Overall job satisfaction index was less than 50 for physicians and 66 for nurses. Patient satisfaction score, however, was high (86) despite the fact that process indicators of service quality were poor. Facility surveys can help strengthen not only the management decision-making process but also the quality of administrative data. Copyright © 2012 John Wiley & Sons, Ltd.

Shielding design of a treatment room for an accelerator-based epithermal neutron irradiation facility for BNCT

International Nuclear Information System (INIS)

Evans, J.F.; Blue, T.E.

1996-01-01

Protecting the facility personnel and the general public from radiation exposure is a primary safety concern of an accelerator-based epithermal neutron irradiation facility. This work makes an attempt at answering the questions open-quotes How much?close quotes and open-quotes What kind?close quotes of shielding will meet the occupational limits of such a facility. Shielding effectiveness is compared for ordinary and barytes concretes in combination with and without borated polyethylene. A calculational model was developed of a treatment room, patient open-quotes scatterer,close quotes and the epithermal neutron beam. The Monte Carlo code, MCNP, was used to compute the total effective dose equivalent rates at specific points of interest outside of the treatment room. A conservative occupational effective dose rate limit of 0.01 mSv h -1 was the guideline for this study. Conservative Monte Carlo calculations show that constructing the treatment room walls with 1.5 m of ordinary concrete, 1.2 m of barytes concrete, 1.0 m of ordinary concrete preceded by 10 cm of 5% boron-polyethylene, or 0.8 m of barytes concrete preceded by 10 cm of 5% boron-polyethylene will adequately protect facility personnel. 20 refs., 8 figs., 2 tabs

Guidelines for Risk-Based Changeover of Biopharma Multi-Product Facilities.

Science.gov (United States)

Lynch, Rob; Barabani, David; Bellorado, Kathy; Canisius, Peter; Heathcote, Doug; Johnson, Alan; Wyman, Ned; Parry, Derek Willison

2018-01-01

In multi-product biopharma facilities, the protection from product contamination due to the manufacture of multiple products simultaneously is paramount to assure product quality. To that end, the use of traditional changeover methods (elastomer change-out, full sampling, etc.) have been widely used within the industry and have been accepted by regulatory agencies. However, with the endorsement of Quality Risk Management (1), the use of risk-based approaches may be applied to assess and continuously improve established changeover processes. All processes, including changeover, can be improved with investment (money/resources), parallel activities, equipment design improvements, and standardization. However, processes can also be improved by eliminating waste. For product changeover, waste is any activity not needed for the new process or that does not provide added assurance of the quality of the subsequent product. The application of a risk-based approach to changeover aligns with the principles of Quality Risk Management. Through the use of risk assessments, the appropriate changeover controls can be identified and controlled to assure product quality is maintained. Likewise, the use of risk assessments and risk-based approaches may be used to improve operational efficiency, reduce waste, and permit concurrent manufacturing of products. © PDA, Inc. 2018.

Simulation based assembly and alignment process ability analysis for line replaceable units of the high power solid state laser facility

International Nuclear Information System (INIS)

Wang, Junfeng; Lu, Cong; Li, Shiqi

2016-01-01

Highlights: • Discrete event simulation is applied to analyze the assembly and alignment process ability of LRUs in SG-III facility. • The overall assembly and alignment process of LRUs with specific characteristics is described. • An extended-directed graph is proposed to express the assembly and alignment process of LRUs. • Different scenarios have been simulated to evaluate assembling process ability of LRUs and decision making is supported to ensure the construction millstone. - Abstract: Line replaceable units (LRUs) are important components of the very large high power solid state laser facilities. The assembly and alignment process ability of LRUs will impact the construction milestone of facilities. This paper describes the use of discrete event simulation method for assembly and alignment process analysis of LRUs in such facilities. The overall assembly and alignment process for LRUs is presented based on the layout of the optics assembly laboratory and the process characteristics are analyzed. An extended-directed graph is proposed to express the assembly and alignment process of LRUs. Taking the LRUs of disk amplifier system in Shen Guang-III (SG-III) facility as the example, some process simulation models are built based on the Quest simulation platform. The constraints, such as duration, equipment, technician and part supply, are considered in the simulation models. Different simulation scenarios have been carried out to evaluate the assembling process ability of LRUs. The simulation method can provide a valuable decision making and process optimization tool for the optics assembly laboratory layout and the process working out of such facilities.

Simulation based assembly and alignment process ability analysis for line replaceable units of the high power solid state laser facility

Energy Technology Data Exchange (ETDEWEB)

Wang, Junfeng; Lu, Cong; Li, Shiqi, E-mail: sqli@hust.edu.cn

2016-11-15

Highlights: • Discrete event simulation is applied to analyze the assembly and alignment process ability of LRUs in SG-III facility. • The overall assembly and alignment process of LRUs with specific characteristics is described. • An extended-directed graph is proposed to express the assembly and alignment process of LRUs. • Different scenarios have been simulated to evaluate assembling process ability of LRUs and decision making is supported to ensure the construction millstone. - Abstract: Line replaceable units (LRUs) are important components of the very large high power solid state laser facilities. The assembly and alignment process ability of LRUs will impact the construction milestone of facilities. This paper describes the use of discrete event simulation method for assembly and alignment process analysis of LRUs in such facilities. The overall assembly and alignment process for LRUs is presented based on the layout of the optics assembly laboratory and the process characteristics are analyzed. An extended-directed graph is proposed to express the assembly and alignment process of LRUs. Taking the LRUs of disk amplifier system in Shen Guang-III (SG-III) facility as the example, some process simulation models are built based on the Quest simulation platform. The constraints, such as duration, equipment, technician and part supply, are considered in the simulation models. Different simulation scenarios have been carried out to evaluate the assembling process ability of LRUs. The simulation method can provide a valuable decision making and process optimization tool for the optics assembly laboratory layout and the process working out of such facilities.

Development of small applied accelerator in Tokyo Institute of Technology

CERN Document Server

Hattori, T

2002-01-01

Interdigital-H(IH) Linac was constructed and applied to materials research in the University. IH Linac uses 1.6 MV small tandem pelletron and accelerates ion (>Q/A=1/4) from 240 KeV to 2.4 MeV. The secondary IH Linac was built and increased the energy to 3.4 MeV/u. In order to apply linac to therapy, IH Linac for PET (Position Emission Tomography), Carbon 6 MeV/u Linac for cancer therapy, APF (Alternating Phase Focus)-IH prototype linac, Carbon 2 MeV/u test APF-IH linac were developed. On application to semiconductor and industry, IHQ type MeV ion implantation device, APF-IH type MeV ion implantation device and high-energy electron accelerator were developed. A bone density measurement instrument was developed and the data was proved better values than ordinary instrument. The problems of prototype small accelerator are summarized. (S.Y.)

Image-Based Reconstruction and Analysis of Dynamic Scenes in a Landslide Simulation Facility

Science.gov (United States)

Scaioni, M.; Crippa, J.; Longoni, L.; Papini, M.; Zanzi, L.

2017-12-01

The application of image processing and photogrammetric techniques to dynamic reconstruction of landslide simulations in a scaled-down facility is described. Simulations are also used here for active-learning purpose: students are helped understand how physical processes happen and which kinds of observations may be obtained from a sensor network. In particular, the use of digital images to obtain multi-temporal information is presented. On one side, using a multi-view sensor set up based on four synchronized GoPro 4 Black® cameras, a 4D (3D spatial position and time) reconstruction of the dynamic scene is obtained through the composition of several 3D models obtained from dense image matching. The final textured 4D model allows one to revisit in dynamic and interactive mode a completed experiment at any time. On the other side, a digital image correlation (DIC) technique has been used to track surface point displacements from the image sequence obtained from the camera in front of the simulation facility. While the 4D model may provide a qualitative description and documentation of the experiment running, DIC analysis output quantitative information such as local point displacements and velocities, to be related to physical processes and to other observations. All the hardware and software equipment adopted for the photogrammetric reconstruction has been based on low-cost and open-source solutions.

IMAGE-BASED RECONSTRUCTION AND ANALYSIS OF DYNAMIC SCENES IN A LANDSLIDE SIMULATION FACILITY

Directory of Open Access Journals (Sweden)

M. Scaioni

2017-12-01

Full Text Available The application of image processing and photogrammetric techniques to dynamic reconstruction of landslide simulations in a scaled-down facility is described. Simulations are also used here for active-learning purpose: students are helped understand how physical processes happen and which kinds of observations may be obtained from a sensor network. In particular, the use of digital images to obtain multi-temporal information is presented. On one side, using a multi-view sensor set up based on four synchronized GoPro 4 Black® cameras, a 4D (3D spatial position and time reconstruction of the dynamic scene is obtained through the composition of several 3D models obtained from dense image matching. The final textured 4D model allows one to revisit in dynamic and interactive mode a completed experiment at any time. On the other side, a digital image correlation (DIC technique has been used to track surface point displacements from the image sequence obtained from the camera in front of the simulation facility. While the 4D model may provide a qualitative description and documentation of the experiment running, DIC analysis output quantitative information such as local point displacements and velocities, to be related to physical processes and to other observations. All the hardware and software equipment adopted for the photogrammetric reconstruction has been based on low-cost and open-source solutions.

Characterization of caries progression on dentin after irradiation with Nd:YAG laser by FTIR spectroscopy and fluorescence imaging

Science.gov (United States)

Ana, P. A.; Brito, A. M. M.; Zezell, D. M.; Lins, E. C. C. C.

2015-06-01

Considering the use of high intensity lasers for preventing dental caries, this blind in vitro study evaluated the compositional and fluorescence effects promoted by Nd:YAG laser (λ=1064 nm) when applied for prevention of progression of dentin caries, in association or not with topical application of acidulated phosphate fluoride (APF). Sixty bovine root dentin slabs were prepared and demineralized by 32h in order to create early caries lesions. After, the slabs were distributed into six experimental groups: G1- untreated and not submitted to a pH-cycling model; G2- untreated and submitted to a pH-cycling model; G3- acidulated phosphate fluoride application (APF); G4- Nd:YAG irradiation (84.9 J/cm2, 60 mJ/pulse); G5- treated with Nd:YAG+APF; G6- treated with APF+Nd:YAG. After treatments, the samples of groups G2 to G6 were submitted to a 4-day pH-cycling model in order to simulate the progression of early caries lesions. All samples were characterized by the micro-attenuated total reflection technique of Fourier transformed infrared spectroscopy (μATR-FTIR), using a diamond crystal, and by a fluorescence imaging system (FIS), in which it was used an illuminating system at λ= 405±30 nm. Demineralization promoted reduction in carbonate and phosphate contents, exposing the organic matter; as well, it was observed a significant reduction of fluorescence intensity. Nd:YAG laser promoted additional chemical changes, and increased the fluorescence intensity even with the development of caries lesions. It was concluded that the compositional changes promoted by Nd:YAG, when associated to APF, are responsible for the reduction of demineralization progression observed on root dentin.

Strategic facility planning improves capital decision making.

Science.gov (United States)

Reeve, J R

2001-03-01

A large, Midwestern IDS undertook a strategic facility-planning process to evaluate its facility portfolio and determine how best to allocate future investments in facility development. The IDS assembled a facility-planning team, which initiated the planning process with a market analysis to determine future market demands and identify service areas that warranted facility expansion. The team then analyzed each of the IDS's facilities from the perspective of uniform capacity measurements, highest and best use compared with needs, building condition and investment-worthiness, and facility growth and site development opportunities. Based on results of the analysis, the strategy adopted entailed, in part, shifting some space from inpatient care to ambulatory care services and demolishing and replacing the 11 percent of facilities deemed to be in the worst condition.

In-facility transport code review

International Nuclear Information System (INIS)

Spore, J.W.; Boyack, B.E.; Bohl, W.R.

1996-07-01

The following computer codes were reviewed by the In-Facility Transport Working Group for application to the in-facility transport of radioactive aerosols, flammable gases, and/or toxic gases: (1) CONTAIN, (2) FIRAC, (3) GASFLOW, (4) KBERT, and (5) MELCOR. Based on the review criteria as described in this report and the versions of each code available at the time of the review, MELCOR is the best code for the analysis of in-facility transport when multidimensional effects are not significant. When multi-dimensional effects are significant, GASFLOW should be used

Environmental aspects based on operation performance of nuclear fuel fabrication facilities

International Nuclear Information System (INIS)

2001-07-01

This publication was prepared within the framework of the IAEA Project entitled Development and Upgrading of Guidelines, Databases and Tools for Integrating Comparative Assessment into Energy System Analysis and Policy Making, which included the collection, review and input of data into a database on health and environmental impacts related to operation of nuclear fuel cycle facilities. The objectives of the report included assembling environmental data on operational performance of nuclear fabrication facilities in each country; compiling and arranging the data in a database, which will be easily available to experts and the public; and presenting data that may be of value for future environmental assessment of nuclear fabrication facilities

A simulation based research on chance constrained programming in robust facility location problem

Directory of Open Access Journals (Sweden)

Kaijun Leng

2017-03-01

Full Text Available Since facility location decisions problem include long-term character and potential parameter variations, it is important to consider uncertainty in its modeling. This paper examines robust facility location problem considering supply uncertainty, in which we assume the supply of the facility in the actual operation is not equal to the supply initially established, the supply is subject to random fluctuation. The chance constraints are introduced when formulating the robust facility location model to make sure the system operate properly with a certain probability while the supply fluctuates. The chance constraints are approximated safely by using Hoeffding’s inequality and the problem is transformed to a general deterministic linear programming. Furthermore, how the facility location cost change with confidence level is investigated through a numerical example. The sensitivity analysis is conducted for important parameters of the model and we get the main factors that affect the facility location cost.

Development of a Tandem-Electrostatic-Quadrupole facility for Accelerator-Based Boron Neutron Capture Therapy.

Science.gov (United States)

Kreiner, A J; Castell, W; Di Paolo, H; Baldo, M; Bergueiro, J; Burlon, A A; Cartelli, D; Vento, V Thatar; Kesque, J M; Erhardt, J; Ilardo, J C; Valda, A A; Debray, M E; Somacal, H R; Sandin, J C Suarez; Igarzabal, M; Huck, H; Estrada, L; Repetto, M; Obligado, M; Padulo, J; Minsky, D M; Herrera, M; Gonzalez, S J; Capoulat, M E

2011-12-01

We describe the present status of an ongoing project to develop a Tandem-ElectroStatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based (AB)-BNCT. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction. The machine currently being constructed is a folded TESQ with a high-voltage terminal at 0.6 MV. We report here on the progress achieved in a number of different areas. Copyright © 2011 Elsevier Ltd. All rights reserved.

Study of physical resistance of the disposal facility for accidental artificial event in LLW disposal facility

International Nuclear Information System (INIS)

Ogawa, Suihei; Irie, Masaaki; Uchida, Masahiro

2013-11-01

This report refer to results of examine what follows for structural stability evaluation for the LLW disposal facility in depth over general human activity in underground. Study of physically resistance on the facility for accidental artificial event, namely tunneling an operation facing the disposal facility in future. Physically resistance to excavation of tunneling etc. in disposal facility is studied based on supposing of Tunnel Boring Machine as an excavator, paying attention to reinforcement bar in concrete and steel plate of waste package, as feature of strength in these material differs from rock strength. And it is examined not only resistibility on excavation but also about hard situations of excavation in tunneling works, and namely give thorough consideration to critical quantity of cutting to reinforcement bar and steel plate that could keep resistibility on excavation based on tunneling velocity and limits time furthermore. It requests necessity of evaluation in consider with metal corrosion that status alteration on disposal facility is considered with on timescale. Period of keep on the physically resistance is estimated by velocity of metal corrosion consequently. The physically resistance is kept until metal corrosion reach remaining its material, giving a limits of the physically resistance on inside of facility. Main point of physically resistance in the report will be made the good use of a practice to physically resistance evaluation of in safety assessment. (author)

Geospatial Data Analysis Facility

Data.gov (United States)

Federal Laboratory Consortium — Geospatial application development, location-based services, spatial modeling, and spatial analysis are examples of the many research applications that this facility...

Emission Facilities - Erosion & Sediment Control Facilities

Data.gov (United States)

NSGIC Education | GIS Inventory — An Erosion and Sediment Control Facility is a DEP primary facility type related to the Water Pollution Control program. The following sub-facility types related to...

Service quality in contracted facilities.

Science.gov (United States)

Rabbani, Fauziah; Pradhan, Nousheen Akber; Zaidi, Shehla; Azam, Syed Iqbal; Yousuf, Farheen

2015-01-01

The purpose of this paper is to explore the readiness of contracted and non-contracted first-level healthcare facilities in Pakistan to deliver quality maternal and neonatal health (MNH) care. A balanced scorecard (BSC) was used as the assessment framework. Using a cross-sectional study design, two rural health centers (RHCs) contracted out to Aga Khan Health Service, Pakistan were compared with four government managed RHCs. A BSC was designed to assess RHC readiness to deliver good quality MNH care. In total 20 indicators were developed, representing five BSC domains: health facility functionality, service provision, staff capacity, staff and patient satisfaction. Validated data collection tools were used to collect information. Pearson χ2, Fisher's Exact and the Mann-Whitney tests were applied as appropriate to detect significant service quality differences among the two facilities. Contracted facilities were generally found to be better than non-contracted facilities in all five BSC domains. Patients' inclination for facility-based delivery at contracted facilities was, however, significantly higher than non-contracted facilities (80 percent contracted vs 43 percent non-contracted, p=0.006). The study shows that contracting out initiatives have the potential to improve MNH care. This is the first study to compare MNH service delivery quality across contracted and non-contracted facilities using BSC as the assessment framework.

Environmental Assessment - Construct a Ground-to-Air Transmitter and Receiver (GATR) Facility at Grand Forks Air Force Base

National Research Council Canada - National Science Library

2006-01-01

...) facility on Grand Forks Air Force Base (AFB), North Dakota. The Communication Squadron is preparing to install new GATR communication antennas and systems, for tactical aircraft control and commercial air traffic control...

Accelerator development for a radioactive beam facility based on ATLAS

International Nuclear Information System (INIS)

Shepard, K. W.

1998-01-01

The existing superconducting linac ATLAS is in many respects an ideal secondary beam accelerator for an ISOL (Isotope separator on-line) type radioactive beam facility. Such a facility would require the addition of two major accelerator elements: a low charge state injector for the existing heavy ion linac, and a primary beam accelerator providing 220 MV of acceleration for protons and light ions. Development work for both of these elements, including the option of superconducting cavities for the primary beam accelerator is discussed

Facility-Based Maternal Death in Western Africa: A Systematic Review

OpenAIRE

Nathali Gunawardena; Ghose Bishwajit; Sanni Yaya

2018-01-01

BackgroundFor exploring maternal death, supply and demand-side factors can be characterized by the three delays model developed by Thaddeus and Maine (1994). The model comprises delay in deciding to seek care (delay 1), delay in reaching the health facility (delay 2), and delay in receiving quality care once at the health facility (delay 3). Few studies have comprehensively dealt with the health systems delays that prevent the receipt of timely and appropriate obstetric care once a woman reac...

Accelerator development for a radioactive beam facility based on ATLAS.

Energy Technology Data Exchange (ETDEWEB)

Shepard, K. W.

1998-01-08

The existing superconducting linac ATLAS is in many respects an ideal secondary beam accelerator for an ISOL (Isotope separator on-line) type radioactive beam facility. Such a facility would require the addition of two major accelerator elements: a low charge state injector for the existing heavy ion linac, and a primary beam accelerator providing 220 MV of acceleration for protons and light ions. Development work for both of these elements, including the option of superconducting cavities for the primary beam accelerator is discussed.

Effects of the low-intensity red laser radiation on the fluoride uptake in enamel. A clinical trial

International Nuclear Information System (INIS)

Nakasone, Regina Keiko

2004-01-01

Fluoride has been the most important preventive method on development of the caries. This in vivo study evaluated the effects of low-intensity red laser radiation on the fluoride uptake in enamel. Ten healthy participants were recruited for this study. The two maxillary central incisors of each volunteer to be biopsied were used and divided into 4 groups: group G C (control, which was untreated; group G F (fluoride), which received topical acidulated phosphate fluoride (APF) 1,23% treatment for 4 minutes; group G LF (laser + fluoride), which was irradiated with a low-intensity diode laser (λ= 660 nm and dose= 6 J/cm 2 ) with APF application after irradiation and group G FL (fluoride + laser), which received APF before irradiation using the same parameters as G LF . The determination of fluoride was performed using a fluoride ion electrode after an acid-etch enamel biopsy. The results show a significant increase of the fluoride uptake in enamel for groups G F , G LF and G FL when compared to control group. Although a percentage increase of 57% was observed for G LF with respect to G F , there were no statistical differences among treated groups. These findings suggest that low-intensity laser radiation used before APF could be employed in the clinical practice to prevent dental caries. (author)

Effects of the low-intensity red laser radiation on the fluoride uptake in enamel. A clinical trial; Avaliacao dos efeitos da radiacao laser de emissao vermelha em baixa intensidade na incorporacao de fluor no esmalte. Estudo clinico

Energy Technology Data Exchange (ETDEWEB)

Nakasone, Regina Keiko

2004-07-01

Fluoride has been the most important preventive method on development of the caries. This in vivo study evaluated the effects of low-intensity red laser radiation on the fluoride uptake in enamel. Ten healthy participants were recruited for this study. The two maxillary central incisors of each volunteer to be biopsied were used and divided into 4 groups: group G{sub C} (control, which was untreated; group G{sub F} (fluoride), which received topical acidulated phosphate fluoride (APF) 1,23% treatment for 4 minutes; group G{sub LF} (laser + fluoride), which was irradiated with a low-intensity diode laser ({lambda}= 660 nm and dose= 6 J/cm{sup 2}) with APF application after irradiation and group G{sub FL} (fluoride + laser), which received APF before irradiation using the same parameters as G{sub LF}. The determination of fluoride was performed using a fluoride ion electrode after an acid-etch enamel biopsy. The results show a significant increase of the fluoride uptake in enamel for groups G{sub F}, G{sub LF} and G{sub FL} when compared to control group. Although a percentage increase of 57% was observed for G{sub LF} with respect to G{sub F}, there were no statistical differences among treated groups. These findings suggest that low-intensity laser radiation used before APF could be employed in the clinical practice to prevent dental caries. (author)

Rancang Bangun STIKI Class Facilities E-Complaint

Directory of Open Access Journals (Sweden)

Ni Kadek Ariasih

2017-08-01

Full Text Available STMIK STIKOM Indonesia is one of the institutions in the field of computer-based education. In order to support the effectiveness of the implementation of teaching and learning activities that take place, it is need a service that support the availability of adequate class facilities and complaints services if there are constraints on facilities in the classroom. So far, the management of complaints complaints against classroom facilities or in the labarotorium which is handled by the Household Management Section is still on manua basis. In terms of record and handle complaints it is required information system which called STIKI Class Facilities E-Complaint. This system can assist the Household Management Section in monitoring complaints from the condition of existing room facilities if experiencing problems and also can improve the quality of service in handling complaints. The software development process model used is prototype and Web-based model with PHP and MySQL database.

Fuel Handling Facility Description Document

International Nuclear Information System (INIS)

M.A. LaFountain

2005-01-01

The purpose of the facility description document (FDD) is to establish the requirements and their bases that drive the design of the Fuel Handling Facility (FHF) to allow the design effort to proceed to license application. This FDD is a living document that will be revised at strategic points as the design matures. It identifies the requirements and describes the facility design as it currently exists, with emphasis on design attributes provided to meet the requirements. This FDD was developed as an engineering tool for design control. Accordingly, the primary audience and users are design engineers. It leads the design process with regard to the flow down of upper tier requirements onto the facility. Knowledge of these requirements is essential to performing the design process. It trails the design with regard to the description of the facility. This description is a reflection of the results of the design process to date

General Plan Environmental Assessment for Joint Base Andrews-Naval Air Facility, Washington, Maryland

Science.gov (United States)

2011-04-01

new facility, Building 1535 would be demolished. The new administrative campus would be anchored by the BRAC/NCR facility and will include future...squadron operations facility, Building 1658, provides the anchor to further development of operations-related facilities in this area. The...A!l’ltndm<:r.l b &pp<QVN. Th.it a.:tiGn romplttes MOE’s n:litw of the ()cle, u r~uind by S«tion 9-507 of the E’.nvironmtnt Ankle of !he Annolai.t<l

Tissue Engineering of Cartilage on Ground-Based Facilities

Science.gov (United States)

Aleshcheva, Ganna; Bauer, Johann; Hemmersbach, Ruth; Egli, Marcel; Wehland, Markus; Grimm, Daniela

2016-06-01

Investigations under simulated microgravity offer the opportunity for a better understanding of the influence of altered gravity on cells and the scaffold-free three-dimensional (3D) tissue formation. To investigate the short-term influence, human chondrocytes were cultivated for 2 h, 4 h, 16 h, and 24 h on a 2D Fast-Rotating Clinostat (FRC) in DMEM/F-12 medium supplemented with 10 % FCS. We detected holes in the vimentin network, perinuclear accumulations of vimentin after 2 h, and changes in the chondrocytes shape visualised by F-actin staining after 4 h of FRC-exposure. Scaffold-free cultivation of chondrocytes for 7 d on the Random Positioning Machine (RPM), the FRC and the Rotating Wall Vessel (RWV) resulted in spheroid formation, a phenomenon already known from spaceflight experiments with chondrocytes (MIR Space Station) and thyroid cancer cells (SimBox/Shenzhou-8 space mission). The experiments enabled by the ESA-CORA-GBF programme gave us an optimal opportunity to study gravity-related cellular processes, validate ground-based facilities for our chosen cell system, and prepare long-term experiments under real microgravity conditions in space

Safety of magnetic fusion facilities: Guidance

International Nuclear Information System (INIS)

1996-05-01

This document provides guidance for the implementation of the requirements identified in DOE-STD-6002-96, Safety of Magnetic Fusion Facilities: Requirements. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While the requirements in DOE-STD-6002-96 are generally applicable to a wide range of fusion facilities, this Standard, DOE-STD-6003-96, is concerned mainly with the implementation of those requirements in large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This Standard is oriented toward regulation in the Department of Energy (DOE) environment as opposed to regulation by other regulatory agencies. As the need for guidance involving other types of fusion facilities or other regulatory environments emerges, additional guidance volumes should be prepared. The concepts, processes, and recommendations set forth here are for guidance only. They will contribute to safety at magnetic fusion facilities

Subsurface Facility System Description Document

International Nuclear Information System (INIS)

Eric Loros

2001-01-01

The Subsurface Facility System encompasses the location, arrangement, size, and spacing of the underground openings. This subsurface system includes accesses, alcoves, and drifts. This system provides access to the underground, provides for the emplacement of waste packages, provides openings to allow safe and secure work conditions, and interfaces with the natural barrier. This system includes what is now the Exploratory Studies Facility. The Subsurface Facility System physical location and general arrangement help support the long-term waste isolation objectives of the repository. The Subsurface Facility System locates the repository openings away from main traces of major faults, away from exposure to erosion, above the probable maximum flood elevation, and above the water table. The general arrangement, size, and spacing of the emplacement drifts support disposal of the entire inventory of waste packages based on the emplacement strategy. The Subsurface Facility System provides access ramps to safely facilitate development and emplacement operations. The Subsurface Facility System supports the development and emplacement operations by providing subsurface space for such systems as ventilation, utilities, safety, monitoring, and transportation

How women are treated during facility-based childbirth: development and validation of measurement tools in four countries - phase 1 formative research study protocol.

Science.gov (United States)

Vogel, Joshua P; Bohren, Meghan A; Tunçalp, Özge; Oladapo, Olufemi T; Adanu, Richard M; Baldé, Mamadou Diouldé; Maung, Thae Maung; Fawole, Bukola; Adu-Bonsaffoh, Kwame; Dako-Gyeke, Phyllis; Maya, Ernest Tei; Camara, Mohamed Campell; Diallo, Alfa Boubacar; Diallo, Safiatou; Wai, Khin Thet; Myint, Theingi; Olutayo, Lanre; Titiloye, Musibau; Alu, Frank; Idris, Hadiza; Gülmezoglu, Metin A

2015-07-22

Every woman has the right to dignified, respectful care during childbirth. Recent evidence has demonstrated that globally many women experience mistreatment during labour and childbirth in health facilities, which can pose a significant barrier to women attending facilities for delivery and can contribute to poor birth experiences and adverse outcomes for women and newborns. However there is no clear consensus on how mistreatment of women during childbirth in facilities is defined and measured. We propose using a two-phased, mixed-methods study design in four countries to address these research gaps. This protocol describes the Phase 1 qualitative research activities. We will employ qualitative research methodologies among women, healthcare providers and administrators in the facility catchment areas of two health facilities in each country: Ghana, Guinea, Myanmar and Nigeria. In-depth interviews (IDIs) and focus group discussions (FGDs) will be conducted among women of reproductive age (15-49 years) to explore their perceptions and experiences of facility-based childbirth care, focused on how they were treated by healthcare workers and perceived factors affecting how they were treated. IDIs will also be conducted with healthcare providers of different cadres (e.g.: nurses, midwives, medical officers, specialist obstetricians) and facility administrators working in the selected facilities to explore healthcare providers' perceptions and experiences of facility-based childbirth care and how staff are treated, colleagues and supervisors. Audio recordings will be transcribed and translated to English. Textual data will be analysed using a thematic framework approach and will consist of two levels of analysis: (1) conduct of local analysis workshops with the research assistants in each country; and (2) line-by-line coding to develop a thematic framework and coding scheme. This study serves several roles. It will provide an in-depth understanding of how women are

Theory of the disordered ν =5/2 quantum thermal Hall state: Emergent symmetry and phase diagram

Science.gov (United States)

Lian, Biao; Wang, Juven

2018-04-01

Fractional quantum Hall (FQH) system at Landau level filling fraction ν =5 /2 has long been suggested to be non-Abelian, either Pfaffian (Pf) or antiPfaffian (APf) states by numerical studies, both with quantized Hall conductance σx y=5 e2/2 h . Thermal Hall conductances of the Pf and APf states are quantized at κx y=7 /2 and κx y=3 /2 , respectively, in a proper unit. However, a recent experiment shows the thermal Hall conductance of ν =5 /2 FQH state is κx y=5 /2 . It has been speculated that the system contains random Pf and APf domains driven by disorders, and the neutral chiral Majorana modes on the domain walls may undergo a percolation transition to a κx y=5 /2 phase. In this paper, we do perturbative and nonperturbative analyses on the domain walls between Pf and APf. We show the domain wall theory possesses an emergent SO(4) symmetry at energy scales below a threshold Λ1, which is lowered to an emergent U (1 )×U (1) symmetry at energy scales between Λ1 and a higher value Λ2, and is finally lowered to the composite fermion parity symmetry Z2F above Λ2. Based on the emergent symmetries, we propose a phase diagram of the disordered ν =5 /2 FQH system and show that a κx y=5 /2 phase arises at disorder energy scales Λ >Λ1 . Furthermore, we show the gapped double-semion sector of ND compact domain walls contributes nonlocal topological degeneracy 2ND-1, causing a low-temperature peak in the heat capacity. We implement a nonperturbative method to bootstrap generic topological 1 +1 D domain walls (two-surface defects) applicable to any 2 +1 D non-Abelian topological order. We also identify potentially relevant spin topological quantum field theories (TQFTs) for various ν =5 /2 FQH states in terms of fermionic version of U (1) ±8 Chern-Simons theory ×Z8 -class TQFTs.

Microproteinuria during Opisthorchis viverrini infection: a biomarker for advanced renal and hepatobiliary pathologies from chronic opisthorchiasis.

Directory of Open Access Journals (Sweden)

Prasert Saichua

Full Text Available Approximately 680 million people are at risk of infection with Opisthorchis viverrini (OV and Clonorchis sinensis, with an estimated 10 million infected with OV in Southeast Asia alone. While opisthorchiasis is associated with hepatobiliary pathologies, such as advanced periductal fibrosis (APF and cholangiocarcinoma (CCA, animal models of OV infection show that immune-complex glomerulonephritis is an important renal pathology that develops simultaneously with hepatobiliary pathologies. A cardinal sign of immune-complex glomerulonephritis is the urinary excretion of immunoglobulin G (IgG (microproteinuria. In community-based studies in OV endemic areas along the Chi River in northeastern Thailand, we observed that over half of the participants had urine IgG against a crude OV antigen extract (OV antigen. We also observed that elevated levels of urine IgG to OV antigen were not associated with the intensity of OV infection, but were likely the result of immune-complex glomerulonephritis as seen in animal models of OV infection. Moreover, we observed that urine IgG to OV antigen was excreted at concentrations 21 times higher in individuals with APF and 158 times higher in individuals with CCA than controls. We also observed that elevated urine IgG to OV antigen could identify APF+ and CCA+ individuals from non-cases. Finally, individuals with urine IgG to OV antigen had a greater risk of APF as determined by Odds Ratios (OR = 6.69; 95%CI: 2.87, 15.58 and a greater risk of CCA (OR = 71.13; 95%CI: 15.13, 334.0 than individuals with no detectable level of urine IgG to OV antigen. Herein, we show for the first time the extensive burden of renal pathology in OV endemic areas and that a urine biomarker could serve to estimate risk for both renal and hepatobiliary pathologies during OV infection, i.e., serve as a "syndromic biomarker" of the advanced pathologies from opisthorchiasis.

The Australian National Proton Facility

International Nuclear Information System (INIS)

Jackson, M.; Rozenfeld, A.; Bishop, J.

2002-01-01

Full text: Protons have been used in the treatment of cancer since 1954 and over 30,000 patients have been treated around the world. Their precise dose distribution allows the treatment of small tumours in critical locations such as the base of skull and orbit and is an alternative to stereotactic radiotherapy in other sites. With the development of hospital-based systems in the 1990's, common tumours such as prostate, breast and lung cancer can now also be treated using simple techniques. The therapeutic ratio is improved as the dose to the tumour can be increased while sparing normal tissues. The well defined high dose region and low integral dose compared with photon treatments is a particular advantage in children and other situations where long-term survival is expected and when used in combination with chemotherapy. In January 2002, the NSW Health Department initiated a Feasibility Study for an Australian National Proton Facility. This Study will address the complex medical, scientific, engineering, commercial and legal issues required to design and build a proton facility in Australia. The Facility will be mainly designed for patient treatment but will also provide facilities for biological, physical and engineering research. The proposed facility will have a combination of fixed and rotating beams with an energy range of 70-250 MeV. Such a centre will enable the conduct of randomised clinical trials and a comparison with other radiotherapy techniques such as Intensity Modulated Radiation Therapy. Cost-utility comparisons with other medical treatments will also be made and further facilities developed if the expected benefit is confirmed. When patients are not being treated, the beam will be available for commercial and research purposes. This presentation will summarize the progress of the Study and discuss the important issues that need to be resolved before the Facility is approved and constructed

System integration of RF based negative ion experimental facility at IPR

Science.gov (United States)

Bansal, G.; Bandyopadhyay, M.; Singh, M. J.; Gahlaut, A.; Soni, J.; Pandya, K.; Parmar, K. G.; Sonara, J.; Chakraborty, A.

2010-02-01

The setting up of RF based negative ion experimental facility shall witness the beginning of experiments on the negative ion source fusion applications in India. A 1 MHz RF generator shall launch 100 kW RF power into a single driver on the plasma source to produce a plasma of density ~5 × 1012 cm-3. The source can deliver a negative ion beam of ~10 A with a current density of ~30 mA/cm2 and accelerated to 35 kV through an electrostatic ion accelerator. The experimental system is similar to a RF based negative ion source, BATMAN, presently operating at IPP. The subsystems for source operation are designed and procured principally from indigenous resources, keeping the IPP configuration as a base line. The operation of negative ion source is supported by many subsystems e.g. vacuum pumping system with gate valves, cooling water system, gas feed system, cesium delivery system, RF generator, high voltage power supplies, data acquisition and control system, and different diagnostics. The first experiments of negative ion source are expected to start at IPR from the middle of 2009.

System integration of RF based negative ion experimental facility at IPR

International Nuclear Information System (INIS)

Bansal, G; Bandyopadhyay, M; Singh, M J; Gahlaut, A; Soni, J; Pandya, K; Parmar, K G; Sonara, J; Chakraborty, A

2010-01-01

The setting up of RF based negative ion experimental facility shall witness the beginning of experiments on the negative ion source fusion applications in India. A 1 MHz RF generator shall launch 100 kW RF power into a single driver on the plasma source to produce a plasma of density ∼5 x 10 12 cm -3 . The source can deliver a negative ion beam of ∼10 A with a current density of ∼30 mA/cm 2 and accelerated to 35 kV through an electrostatic ion accelerator. The experimental system is similar to a RF based negative ion source, BATMAN, presently operating at IPP. The subsystems for source operation are designed and procured principally from indigenous resources, keeping the IPP configuration as a base line. The operation of negative ion source is supported by many subsystems e.g. vacuum pumping system with gate valves, cooling water system, gas feed system, cesium delivery system, RF generator, high voltage power supplies, data acquisition and control system, and different diagnostics. The first experiments of negative ion source are expected to start at IPR from the middle of 2009.

340 Waste Handling Facility interim safety basis

International Nuclear Information System (INIS)

Bendixsen, R.B.

1995-01-01

This document establishes the interim safety basis (ISB) for the 340 Waste Handling Facility (340 Facility). An ISB is a documented safety basis that provides a justification for the continued operation of the facility until an upgraded final safety analysis report is prepared that complies with US Department of Energy (DOE) Order 5480.23, Nuclear Safety Analysis Reports. The ISB for the 340 Facility documents the current design and operation of the facility. The 340 Facility ISB (ISB-003) is based on a facility walkdown and review of the design and operation of the facility, as described in the existing safety documentation. The safety documents reviewed, to develop ISB-003, include the following: OSD-SW-153-0001, Operating Specification Document for the 340 Waste Handling Facility (WHC 1990); OSR-SW-152-00003, Operating Limits for the 340 Waste Handling Facility (WHC 1989); SD-RE-SAP-013, Safety Analysis Report for Packaging, Railroad Liquid Waste Tank Cars (Mercado 1993); SD-WM-TM-001, Safety Assessment Document for the 340 Waste Handling Facility (Berneski 1994a); SD-WM-SEL-016, 340 Facility Safety Equipment List (Berneski 1992); and 340 Complex Fire Hazard Analysis, Draft (Hughes Assoc. Inc. 1994)

Comparison Between In-Beam and Offline Positron Emission Tomography Imaging of Proton and Carbon Ion Therapeutic Irradiation at Synchrotron- and Cyclotron-Based Facilities

International Nuclear Information System (INIS)

Parodi, Katia; Bortfeld, Thomas; Haberer, Thomas

2008-01-01

Purpose: The benefit of using dedicated in-beam positron emission tomography (PET) detectors in the treatment room instead of commercial tomographs nearby is an open question. This work quantitatively compares the measurable signal for in-beam and offline PET imaging, taking into account realistic acquisition strategies at different ion beam facilities. Both scenarios of pulsed and continuous irradiation from synchrotron and cyclotron accelerators are considered, because of their widespread use in most carbon ion and proton therapy centers. Methods and Materials: A mathematical framework is introduced to compare the time-dependent amount and spatial distribution of decays from irradiation-induced isotope production. The latter is calculated with Monte Carlo techniques for real proton treatments of head-and-neck and paraspinal tumors. Extrapolation to carbon ion irradiation is based on results of previous phantom experiments. Biologic clearance is modeled taking into account available data from previous animal and clinical studies. Results: Ratios between the amount of physical decays available for in-beam and offline detection range from 40% to 60% for cyclotron-based facilities, to 65% to 110% (carbon ions) and 94% to 166% (protons) at synchrotron-based facilities, and increase when including biologic clearance. Spatial distributions of decays during irradiation exhibit better correlation with the dose delivery and reduced influence of biologic processes. Conclusions: In-beam imaging can be advantageous for synchrotron-based facilities, provided that efficient PET systems enabling detection of isotope decays during beam extraction are implemented. For very short (<2 min) irradiation times at cyclotron-based facilities, a few minutes of acquisition time after the end of irradiation are needed for counting statistics, thus affecting patient throughput

National Ignition Facility site requirements

International Nuclear Information System (INIS)

1996-07-01

The Site Requirements (SR) provide bases for identification of candidate host sites for the National Ignition Facility (NIF) and for the generation of data regarding potential actual locations for the facilities. The SR supplements the NIF Functional Requirements (FR) with information needed for preparation of responses to queries for input to HQ DOE site evaluation. The queries are to include both documents and explicit requirements for the potential host site responses. The Sr includes information extracted from the NIF FR (for convenience), data based on design approaches, and needs for physical and organization infrastructure for a fully operational NIF. The FR and SR describe requirements that may require new construction or may be met by use or modification of existing facilities. The SR do not establish requirements for NIF design or construction project planning. The SR document does not constitute an element of the NIF technical baseline

CANISTER HANDLING FACILITY DESCRIPTION DOCUMENT

Energy Technology Data Exchange (ETDEWEB)

J.F. Beesley

2005-04-21

The purpose of this facility description document (FDD) is to establish requirements and associated bases that drive the design of the Canister Handling Facility (CHF), which will allow the design effort to proceed to license application. This FDD will be revised at strategic points as the design matures. This FDD identifies the requirements and describes the facility design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This FDD is an engineering tool for design control; accordingly, the primary audience and users are design engineers. This FDD is part of an iterative design process. It leads the design process with regard to the flowdown of upper tier requirements onto the facility. Knowledge of these requirements is essential in performing the design process. The FDD follows the design with regard to the description of the facility. The description provided in this FDD reflects the current results of the design process.

CANISTER HANDLING FACILITY DESCRIPTION DOCUMENT

International Nuclear Information System (INIS)

Beesley. J.F.

2005-01-01

The purpose of this facility description document (FDD) is to establish requirements and associated bases that drive the design of the Canister Handling Facility (CHF), which will allow the design effort to proceed to license application. This FDD will be revised at strategic points as the design matures. This FDD identifies the requirements and describes the facility design, as it currently exists, with emphasis on attributes of the design provided to meet the requirements. This FDD is an engineering tool for design control; accordingly, the primary audience and users are design engineers. This FDD is part of an iterative design process. It leads the design process with regard to the flowdown of upper tier requirements onto the facility. Knowledge of these requirements is essential in performing the design process. The FDD follows the design with regard to the description of the facility. The description provided in this FDD reflects the current results of the design process

The Berkeley Accelerator Space Effects (BASE) Facility - A new mission for the 88-Inch Cyclotron at LBNL

International Nuclear Information System (INIS)

McMahan, M.A.

2005-01-01

In FY04, the 88-Inch Cyclotron began a new operating mode that supports a local research program in nuclear science, R and D in accelerator technology and a test facility for the National Security Space (NSS) community (the US Air Force and NRO). The NSS community (and others on a cost recovery basis) can take advantage of both the light- and heavy-ion capabilities of the cyclotron to simulate the space radiation environment. A significant portion of this work involves the testing of microcircuits for single event effects. The experimental areas within the building that are used for the radiation effects testing are now called the Berkeley Accelerator Space Effects (BASE) Facility. Improvements to the facility to provide increased reliability, quality assurance and new capabilities are underway and will be discussed. These include a 16 A MeV 'cocktail' of beams for heavy ion testing, a neutron beam, more robust dosimetry, and other upgrades

Beam dynamics of alternating-phase-focused linac

CERN Document Server

Iwata, Y; Kapin, V

2004-01-01

A simple method to find an array of synchronous phases for alternating-phase-focused (APF) linacs is presented. The phase array is described with a smooth function having free parameters. With a set of the parameters, a simulation on the beam dynamics was made and distributions of the six-dimensional phase spaces were calculated for each set of the parameters. The parameters were varied, and numbers of the simulations have been performed. An optimum set of the parameters were determined so that the simulations of the beam dynamics yield large acceptances and small emittances of the extracted beams. Since the APF linac can provide both axial and radial stability of beams just with the rf acceleration-field, no additional focusing element inside of drift tubes are necessary. Comparing with conventional linacs having focusing elements, it has advantage in construction and operation costs as well as its acceleration rate. Therefore, the APF linacs would be suited for an injector of medical synchrotrons. A practic...

Facile screening of potential xenoestrogens by an estrogen receptor-based reusable optical biosensor.

Science.gov (United States)

Liu, Lanhua; Zhou, Xiaohong; Lu, Yun; Shan, Didi; Xu, Bi; He, Miao; Shi, Hanchang; Qian, Yi

2017-11-15

The apparent increase in hormone-induced cancers and disorders of the reproductive tract has led to a growing demand for new technologies capable of screening xenoestrogens. We reported an estrogen receptor (ER)-based reusable fiber biosensor for facile screening estrogenic compounds in environment. The bioassay is based on the competition of xenoestrogens with 17β-estradiol (E 2 ) for binding to the recombinant receptor of human estrogen receptor α (hERα) protein, leaving E 2 free to bind to fluorophore-labeled anti-E 2 monoclonal antibody. Unbound anti-E 2 antibody then binds to the immobilized E 2 -protein conjugate on the fiber surface, and is detected by fluorescence emission induced by evanescent field. As expected, the stronger estrogenic activity of xenoestrogen would result in the weaker fluorescent signal. Three estrogen-agonist compounds, diethylstilbestrol (DES), 4-n-nonylphenol (NP) and 4-n-octylphenol (OP), were chosen as a paradigm for validation of this assay. The rank order of estrogenic potency determined by this biosensor was DES>OP>NP, which were consistent with the published results in numerous studies. Moreover, the E 2 -protein conjugate modified optical fiber was robust enough for over 300 sensing cycles with the signal recoveries ranging from 90% to 100%. In conclusion, the biosensor is reusable, reliable, portable and amenable to on-line operation, providing a facile, efficient and economical alternative to screen potential xenoestrogens in environment. Copyright © 2017 Elsevier B.V. All rights reserved.

URAM-2 Cryogenic Irradiation Facility

CERN Document Server

Shabalin, E P; Kulikov, S A; Kulagin, E N; Melihov, V V; Belyakov, A A; Golovanov, L B; Borzunov, Yu T; Konstantinov, V I; Androsov, A V

2002-01-01

The URAM-2 irradiation facility has been built and mounted at the channel No. 3 of the IBR-2 reactor. It was constructed for study of radiolysis effects by fast neutron irradiation in some suitable for effective cold neutron production materials (namely: solid methane, methane hydrate, water ice, etc.). The facility cooling system is based on using liquid helium as a coolant material. The original charging block of the rig allows the samples to be loaded by condensing gas into irradiation cavity or by charging beads of ice prepared before. Preliminary tests for each facility block and assembling them at the working position were carried out. Use of the facility for study accumulation of chemical energy under irradiation at low temperature in materials mentioned above and its spontaneous release was started.

Campania Region's Educational Quality Facilities Project

Science.gov (United States)

Ponti, Giorgio

2009-01-01

This article describes the Educational Quality Facilities project undertaken by Italy's Campania Region to provide quality facilities to all of its communities basing new spaces on the "Flexible Learning Module". The objectives of the five-year project are to: build and equip new educational spaces; improve the quality of existing…

The Effectiveness of Urban Green Spaces and Socio-Cultural Facilities

Directory of Open Access Journals (Sweden)

Mehmet Faruk Altunkasa

2017-04-01

Full Text Available This paper aims to develop a theoretical approach for mapping and determining the effectiveness of green spaces and socio-cultural facilities as providers of urban ecosystem services and urban services in the case of Adana, Turkey. Firstly, green spaces and socio-cultural facilities per capita have been determined and indexed for the neighbourhoods in the city. Then, a distance-based method for estimating the effectiveness of these facilities was used. The distances between the various neighbourhoods and between a given facility and the farthest threshold have been measured and these values have been used to determine the facility effectiveness change value for each neighbourhood. Then, effective values have been calculated and indexed by incorporating the green space and socio-cultural facility values and the effectiveness change values for the neighbourhoods. Finally, point-based effective green spaces and socio-cultural facilities index values have been converted to continuous surface values in a GIS (geographic information system environment in order to utilize as a base map for urban physical planning purposes. According to the outcomes of this study, the distribution of green spaces and socio-cultural facilities of the neighbourhoods are imbalanced and index values of these facilities range in between 45 and 84 out of 100.

National Biomedical Tracer Facility. Project definition study

International Nuclear Information System (INIS)

Schafer, R.

1995-01-01

We request a $25 million government-guaranteed, interest-free loan to be repaid over a 30-year period for construction and initial operations of a cyclotron-based National Biomedical Tracer Facility (NBTF) in North Central Texas. The NBTF will be co-located with a linear accelerator-based commercial radioisotope production facility, funded by the private sector at approximately $28 million. In addition, research radioisotope production by the NBTF will be coordinated through an association with an existing U.S. nuclear reactor center that will produce research and commercial radioisotopes through neutron reactions. The combined facilities will provide the full range of technology for radioisotope production and research: fast neutrons, thermal neutrons, and particle beams (H - , H + , and D + ). The proposed NBTF facility includes an 80 MeV, 1 mA H - cyclotron that will produce proton-induced (neutron deficient) research isotopes

Radioactive ion beam facilities in Europe

International Nuclear Information System (INIS)

Blumenfeld, Y.

2008-01-01

The past two decades have seen extraordinarily rapid development of radioactive beam physics throughout the world and in particular in Europe. The important scientific advances have stemmed from a large number of facilities. Previously existing stable beam machines have been adapted to produce rare isotope beams and dedicated facilities have come on-line. This talk gives an overview of the present European installations highlighting their complementary nature. The European roadmap calls for the construction of two next generation facilities: FAIR making use of projectile fragmentation and EURISOL based on the ISOL technique. The future FAIR facility will be described and the path towards EURISOL presented in the light of the construction of 'intermediate' generation facilities SPIRAL2, HIE ISOLDE and SPES and results from the ongoing EURISOL Design Study.

Outline of the report on the seismic safety examination of nuclear facilities based on the 1995 Hyogoken-Nanbu earthquake (tentative translation) - September 1995

International Nuclear Information System (INIS)

2003-01-01

From the standpoint of thoroughly confirming the seismic safety of nuclear facilities, Nuclear Safety Commission established an Examination Committee on the Seismic Safety of Nuclear Power Reactor Facilities (hereinafter called Seismic Safety Examination Committee) based on the 1995 Hyogoken-Nanbu Earthquake on January 19, 1995, two days after the occurrence of the earthquake, in order to examine the validity of related guidelines on the seismic design to be used for the safety examination. This report outlines the results of the examinations by the Seismic Safety Examination Committee: basic principle of examinations at the seismic safety examination committee, overview on the related guidelines of the seismic design, information and knowledge obtained on the 1995 Hyogoken-Nanbu earthquake, examination of validity of the guidelines based on various information of the Hyogoken-Nanbu earthquake. The Seismic Design Examination Committee surveyed the related guidelines on seismic design, selected the items to be examined, and examined on those items based on the knowledge obtained from the Hyogoken-Nanbu Earthquake. As a result, the Committee confirmed that the validity of the guidelines regulating the seismic design of nuclear facilities is not impaired even though on the basis of the Hyogoken-Nanbu Earthquake. However, the people related to the nuclear facilities may not be content with the above result, but continuously put efforts in doing the following matters to improve furthermore the reliability of seismic design of nuclear facilities by always reflecting the latest knowledge on the seismic design. 1) - The people related to nuclear facilities must seriously accept the fact that valuable knowledge could be obtained from the Hyogoken-Nanbu Earthquake, try to study and analyze the obtained data, and reflect the results of investigations, studies, and examinations conducted appropriately to the seismic design of nuclear facilities referring to the investigations

Environmental Compliance and Pollution Prevention Training Manual for Campus-Based Organizations--Operational and Facility Maintenance Personnel.

Science.gov (United States)

New York State Dept. of Environmental Conservation, Albany.

This manual was designed to be used as part of the Workshop on Environmental Compliance and Pollution Prevention for campus-based facilities. It contains basic information on New York state and federal laws, rules, and regulations for protecting the environment. The information presented is a summary with emphasis on those items believed to be…

Development of high power CW and pulsed RF test facility based on 1 MW, 352.2 MHz klystron amplifier

International Nuclear Information System (INIS)

Badapanda, M.K.; Tripathi, Akhilesh; Upadhyay, Rinki; Rao, J.N.; Tiwari, Ashish; Jain, Akhilesh; Lad, M.R.; Hannurkar, P.R.

2013-01-01

A high power 1 MW, 352.2 MHz RF Test facility having CW and Pulse capability is being developed at Raja Ramanna Centre for Advanced Technology (RRCAT), Indore for performance evaluation of various RF components, accelerating structures and related subsystems. Thales make 1 MW, 352.2 MHz klystron amplifier (TH 2089) will be employed in this high power test facility, which is thoroughly tested for its performance parameters at rated operating conditions. Auxiliary power supplies like filament, electromagnet, ion pump and mod anode power supply as well as 200 W solid state driver amplifier necessary for this high power test facility have been developed. A high voltage floating platform is created for floating filament and mod anode power supplies. Interconnection of various power supplies and other subsystems of this test facility are being carried out. A high voltage 100 kV, 25 Amp DC crowbar less power supply and low conductivity water (LCW) plant required for this klystron amplifier are in advanced stage of development. NI make cRIO 9081 real time (RT) controller based control and interlock system has been developed to realize proper sequence of operation of various power supplies and to monitor the status of crucial parameters in this test facility. This RF test facility will provide confidence for development of RF System of future accelerators like SNS and ADSS. (author)

The decommissioning of nuclear facilities; Le demantelement des installations nucleaires de base

Energy Technology Data Exchange (ETDEWEB)

Niel, J.Ch.; Rieu, J.; Lareynie, O.; Delrive, L.; Vallet, J.; Girard, A.; Duthe, M.; Lecomte, C.; Rozain, J.P.; Nokhamzon, J.G.; Davoust, M.; Eyraud, J.L.; Bernet, Ph.; Velon, M.; Gay, A.; Charles, Th.; Leschaeva, M.; Dutzer, M.; Maocec, Ch.; Gillet, G.; Brut, F.; Dieulot, M.; Thuillier, D.; Tournebize, F.; Fontaine, V.; Goursaud, V.; Birot, M.; Le Bourdonnec, Th.; Batandjieva, B.; Theis, St.; Walker, St.; Rosett, M.; Cameron, C.; Boyd, A.; Aguilar, M.; Brownell, H.; Manson, P.; Walthery, R.; Wan Laer, W.; Lewandowski, P.; Dorms, B.; Reusen, N.; Bardelay, J.; Damette, G.; Francois, P.; Eimer, M.; Tadjeddine, A.; Sene, M.; Sene, R

2008-11-15

This file includes five parts: the first part is devoted to the strategies of the different operators and includes the following files: the decommissioning of nuclear facilities Asn point of view, decommissioning of secret nuclear facilities, decommissioning at the civil Cea strategy and programs, EDF de-construction strategy, Areva strategy for decommissioning of nuclear facilities; the second one concerns the stakes of dismantling and includes the articles as follow: complete cleanup of buildings structures in nuclear facilities, decommissioning of nuclear facilities and safety assessment, decommissioning wastes management issues, securing the financing of long-term decommissioning and waste management costs, organizational and human factors in decommissioning projects, training for the decommissioning professions: the example of the Grenoble University master degree; the third part is devoted to the management of dismantling work sites and includes the different articles as follow: decommissioning progress at S.I.C.N. plant, example of decommissioning work site in Cea Grenoble: Siloette reactor decommissioning, matters related to decommissioning sites, decommissioning of french nuclear installations: the viewpoint of a specialist company, specificities of inspections during decommissioning: the Asn inspector point of view; the fourth part is in relation with the international approach and includes as follow: IAEA role in establishing a global safety regime on decommissioning, towards harmonization of nuclear safety practices in Europe: W.E.N.R.A. and the decommissioning of nuclear facilities, EPA superfund program policy for decontamination and decommissioning, progress with remediation at Sellafield, progress and experiences from the decommissioning of the Eurochemic reprocessing plant in Belgium, activities of I.R.S.N. and its daughter company Risk-audit I.r.s.n./G.r.s. international in the field of decommissioning of nuclear facilities in eastern countries

SPES: A new cyclotron-based facility for research and applications with high-intensity beams

Science.gov (United States)

Maggiore, M.; Campo, D.; Antonini, P.; Lombardi, A.; Manzolaro, M.; Andrighetto, A.; Monetti, A.; Scarpa, D.; Esposito, J.; Silvestrin, L.

2017-06-01

In 2016, Laboratori Nazionali di Legnaro (Italy) started the commissioning of a new accelerator facility based on a high-power cyclotron able to deliver proton beams up to 70 MeV of energy and 700 μA current. Such a machine is the core of the Selective Production of Exotic Species (SPES) project whose main goal is to provide exotics beam for nuclear and astrophysics research and to deliver high-intensity proton beams for medical applications and neutrons generator.

Information base for waste repository design. Volume 5. Decommissioning of underground facilities. Technical report

International Nuclear Information System (INIS)

Giuffre, M.S.; Plum, R.L.; Koplik, C.M.; Talbot, R.

1979-03-01

This report is Volume 5 of a seven volume document on nuclear waste repository design issues. This report discusses the requirements for decommissioning a deep underground facility for the disposal of radioactive waste. The techniques for sealing the mined excavations are presented and an information base on potential backfill materials is provided. Possible requirements for monitoring the site are discussed. The performance requirements for backfill materials are outlined. The advantages and disadvantages of each sealing method are stated

Combined visualization for noise mapping of industrial facilities based on ray-tracing and thin plate splines

Science.gov (United States)

Ovsiannikov, Mikhail; Ovsiannikov, Sergei

2017-01-01

The paper presents the combined approach to noise mapping and visualizing of industrial facilities sound pollution using forward ray tracing method and thin-plate spline interpolation. It is suggested to cauterize industrial area in separate zones with similar sound levels. Equivalent local source is defined for range computation of sanitary zones based on ray tracing algorithm. Computation of sound pressure levels within clustered zones are based on two-dimension spline interpolation of measured data on perimeter and inside the zone.

Regionalised tertiary psychiatric residential facilities.

Science.gov (United States)

Lesage, Alain; Groden, David; Goldner, Elliot M; Gelinas, Daniel; Arnold, Leslie M

2008-01-01

Psychiatric hospitals remain the main venue for long-term mental health care and, despite widespread closures and downsizing, no country that built asylums in the last century has done away with them entirely--with the recent exception of Italy. Differentiated community-based residential alternatives have been developed over the past decades, with staffing levels that range from full-time professional, to daytime only, to part-time/on-call. This paper reviews the characteristics of community-based psychiatric residential care facilities as an alternative to long-term care in psychiatric hospitals. It describes five factors decision makers should consider: 1. number of residential places needed; 2. staffing levels; 3. physical setting; 4. programming; and 5. governance and financing. In Italy, facilities with full-time professional staff have been developed since the mid-1990s to accommodate the last cohorts of patients discharged from psychiatric hospitals. In the United Kingdom, experiments with hostel wards since the 1980s have shown that home-like, small-scale facilities with intensive treatment and rehabilitation programming can be effective for the most difficult-to-place patients. More recently in Australia, Community Care Units (CCUs) have been applying this concept. In the Canadian province of British Columbia (BC), Tertiary Psychiatric Residential Facilities (TPRFs) have been developed as part of an effort to regionalise health and social services and downsize and ultimately close its only psychiatric hospital. This type of service must be further developed in addition to the need for forensic, acute-care and intermediate-level beds, as well as for community-based care such as assertive community treatment and intensive case management. All these types of services, together with long-term community-based residential care, constitute the elements of a balanced mental health care system. As part of a region's balanced mental health care plan, these Tertiary

Feasibility study for a recirculating linac-based facility for femtosecond dynamics

Energy Technology Data Exchange (ETDEWEB)

Corlett, J.N.; Barry, W.; Barletta, W.A.; Byrd, J.M.; DeSantis, S.; Doolittle, L.; Fawley, W.; Green, M.A.; Hartman, N.; Heimann, P.; Kairan, D.; Kujawski, E.; Li, D.; Lidia, S.; Luft, P.; McClure, R.; Parmigiani, F.; Petroff, Y.; Pirkl, W.; Placidi, M.; Reavill, D.; Reichel, I.; Rimmer, R.A.; Ratti, A.; Robinson, K.E.; Sannibale, F.; Schoenlein, R.; Staples, J.; Tanabe, J.; Truchlikova, D.; Wan, W.; Wang, S.; Wells, R.; Wolski, A.; Zholents, A.

2002-12-21

LBNL is pursuing design studies and the scientific program for a facility dedicated to the production of x-ray pulses with ultra-short time duration, for application in dynamical studies of processes in physics, biology, and chemistry. The proposed x-ray facility has the short x-ray pulse length ({approx}60 fs FWHM) necessary to study very fast dynamics, high flux (up to approximately 10E11 photons/sec/0.1 percentBW) to study weakly scattering systems, and tuneability over 1-12 keV photon energy. The hard x-ray photon production section of the machine accommodates seven 2-m long undulators. Design studies for longer wavelength sources, using high-gain harmonic generation, are in progress. The x-ray pulse repetition rate of 10 kHz is matched to studies of dynamical processes (initiated by ultra-short laser pulses) that typically have a long recovery time or are not generally cyclic or reversible and need time to allow relaxation, replacement, or flow of the sample. The technique for producing ultra-short x-ray pulses uses relatively long electron bunches to minimize high-peak-current collective effects, and the ultimate x-ray duration is achieved by a combination of bunch manipulation and optical compression. Synchronization of x-ray pulses to sample excitation signals is expected to be of order 50 - 100 fs. Techniques for making use of the recirculating geometry to provide beam-based signals from early passes through the machine are being studied.

Feasibility study for a recirculating linac-based facility for femtosecond dynamics

International Nuclear Information System (INIS)

Corlett, J.N.; Barry, W.; Barletta, W.A.; Byrd, J.M.; DeSantis, S.; Doolittle, L.; Fawley, W.; Green, M.A.; Hartman, N.; Heimann, P.; Kairan, D.; Kujawski, E.; Li, D.; Lidia, S.; Luft, P.; McClure, R.; Parmigiani, F.; Petroff, Y.; Pirkl, W.; Placidi, M.; Reavill, D.; Reichel, I.; Rimmer, R.A.; Ratti, A.; Robinson, K.E.; Sannibale, F.; Schoenlein, R.; Staples, J.; Tanabe, J.; Truchlikova, D.; Wan, W.; Wang, S.; Wells, R.; Wolski, A.; Zholents, A.

2002-01-01

LBNL is pursuing design studies and the scientific program for a facility dedicated to the production of x-ray pulses with ultra-short time duration, for application in dynamical studies of processes in physics, biology, and chemistry. The proposed x-ray facility has the short x-ray pulse length (∼60 fs FWHM) necessary to study very fast dynamics, high flux (up to approximately 10E11 photons/sec/0.1 percentBW) to study weakly scattering systems, and tuneability over 1-12 keV photon energy. The hard x-ray photon production section of the machine accommodates seven 2-m long undulators. Design studies for longer wavelength sources, using high-gain harmonic generation, are in progress. The x-ray pulse repetition rate of 10 kHz is matched to studies of dynamical processes (initiated by ultra-short laser pulses) that typically have a long recovery time or are not generally cyclic or reversible and need time to allow relaxation, replacement, or flow of the sample. The technique for producing ultra-short x-ray pulses uses relatively long electron bunches to minimize high-peak-current collective effects, and the ultimate x-ray duration is achieved by a combination of bunch manipulation and optical compression. Synchronization of x-ray pulses to sample excitation signals is expected to be of order 50 - 100 fs. Techniques for making use of the recirculating geometry to provide beam-based signals from early passes through the machine are being studied

Information security management system planning for CBRN facilities

Energy Technology Data Exchange (ETDEWEB)

Lenaeu, Joseph D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); O' Neil, Lori Ross [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Leitch, Rosalyn M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Glantz, Clifford S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Landine, Guy P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bryant, Janet L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lewis, John [National Nuclear Lab., Workington (United Kingdom); Mathers, Gemma [National Nuclear Lab., Workington (United Kingdom); Rodger, Robert [National Nuclear Lab., Workington (United Kingdom); Johnson, Christopher [National Nuclear Lab., Workington (United Kingdom)

2015-12-01

The focus of this document is to provide guidance for the development of information security management system planning documents at chemical, biological, radiological, or nuclear (CBRN) facilities. It describes a risk-based approach for planning information security programs based on the sensitivity of the data developed, processed, communicated, and stored on facility information systems.

Information security management system planning for CBRN facilities

International Nuclear Information System (INIS)

Lenaeu, Joseph D.; O'Neil, Lori Ross; Leitch, Rosalyn M.; Glantz, Clifford S.; Landine, Guy P.; Bryant, Janet L.; Lewis, John; Mathers, Gemma; Rodger, Robert; Johnson, Christopher

2015-01-01

The focus of this document is to provide guidance for the development of information security management system planning documents at chemical, biological, radiological, or nuclear (CBRN) facilities. It describes a risk-based approach for planning information security programs based on the sensitivity of the data developed, processed, communicated, and stored on facility information systems.

Active power filter for harmonic compensation using a digital dual-mode-structure repetitive control approach

DEFF Research Database (Denmark)

Zou, Zhixiang; Wang, Zheng; Cheng, Ming

2012-01-01

This paper presents an digital dual-mode-structure repetitive control approach for the single-phase shunt active power filter (APF), which aims to enhance the tracking ability and eliminate arbitrary order harmonic. The proposed repetitive control scheme blends the characteristics of both odd......-harmonic repetitive control and even-harmonic repetitive control. Moreover, the convergence rate is faster than conventional repetitive controller. Additionally, the parameters have been designed and optimized for the dual-mode structure repetitive control to improve the performance of APF system. Experimental...

BARC-TIFR Pelletron Linac facility

International Nuclear Information System (INIS)

Gore, J.A.; Gupta, A.K.; Saxena, A.

2017-01-01

The Pelletron Accelerator, set up as a collaborative project between the Bhabha Atomic Research Centre and the Tata Institute of Fundamental Research, has been serving as the workhorse for the heavy ion accelerator based research in India since its commissioning in December 30, 1988. The facility was augmented with an indigenously developed superconducting Linac booster to enhance the energy of the Pelletron accelerated beams and was fully commissioned on November 28, 2007. The augmented facility is renamed as Pelletron Linac facility (PLF). While the PLF is predominantly utilized by the experimental users from BARC and TIFR, the users include researchers from other research institutions and universities within India and abroad

Facile Fabrication of Durable Copper-Based Superhydrophobic Surfaces via Electrodeposition.

Science.gov (United States)

Jain, R; Pitchumani, R

2018-03-13

Superhydrophobic surfaces have myriad industrial applications, yet their practical utilization has been limited by their poor mechanical durability and longevity. We present a low-cost, facile process to develop superhydrophobic copper-based coatings via an electrodeposition route, that addresses this limitation. Through electrodeposition, a stable, multiscale, cauliflower shaped fractal morphology was obtained and upon modification by stearic acid, the prepared coatings show extreme water repellency with contact angle of 162 ± 2° and roll-off angle of about 3°. Systematic studies are presented on coatings fabricated under different processing conditions to demonstrate good durability, mechanical and underwater stability, corrosion resistance, and self-cleaning effect. The study also presents an approach for rejuvenation of slippery superhydrophobic nature (roll-off angle <10°) on the surfaces after long-term water immersion. The presented process can be scaled to larger, durable coatings with controllable wettability for diverse applications.

48 CFR 215.404-71-4 - Facilities capital employed.

Science.gov (United States)

2010-10-01

... encouraging and rewarding capital investment in facilities that benefit DoD. It recognizes both the facilities... anticipated industrial base enhancing benefits resulting from the facilities capital investment, including— (A... investment recovery, such as termination protection clauses and capital investment indemnification. (2) Above...

The commissioning of the BRISOL facility

Energy Technology Data Exchange (ETDEWEB)

Tang, B., E-mail: tangb364@126.com; Cui, B.; Chen, L.; Huang, Q.; Ma, R.; Ma, Y.; Ma, X.; Zhang, T.; Jiang, W.

2016-06-01

The Beijing Radioactive ion beam facility Isotope Separator On-Line (BRISOL) is a radioactive ion beam facility based on a 100 MeV cyclotron providing 100 μA proton beam bombarding a thick target to produce radioactive nuclei, which are transferred into an ion source to produce a singly-charged ion beam. The construction and installation of BRISOL was completed in March 2014. The commissioning of the BRISOL facility with stable beams has been carried out in the last year. The ion source, the separator and the beam-line were tested with a {sup 39}K{sup +} stable beam. The tests and the current status of the BRISOL facility will be presented in this paper.

Fuel Supply Shutdown Facility Interim Operational Safety Requirements

International Nuclear Information System (INIS)

BENECKE, M.W.

2000-01-01

The Interim Operational Safety Requirements for the Fuel Supply Shutdown (FSS) Facility define acceptable conditions, safe boundaries, bases thereof, and management of administrative controls to ensure safe operation of the facility

National Biomedical Tracer Facility. Project definition study

Energy Technology Data Exchange (ETDEWEB)

Schafer, R.

1995-02-14

We request a $25 million government-guaranteed, interest-free loan to be repaid over a 30-year period for construction and initial operations of a cyclotron-based National Biomedical Tracer Facility (NBTF) in North Central Texas. The NBTF will be co-located with a linear accelerator-based commercial radioisotope production facility, funded by the private sector at approximately $28 million. In addition, research radioisotope production by the NBTF will be coordinated through an association with an existing U.S. nuclear reactor center that will produce research and commercial radioisotopes through neutron reactions. The combined facilities will provide the full range of technology for radioisotope production and research: fast neutrons, thermal neutrons, and particle beams (H{sup -}, H{sup +}, and D{sup +}). The proposed NBTF facility includes an 80 MeV, 1 mA H{sup -} cyclotron that will produce proton-induced (neutron deficient) research isotopes.

Plan for 3-D full-scale earthquake testing facility

International Nuclear Information System (INIS)

Ohtani, K.

2001-01-01

Based on the lessons learnt from the Great Hanshin-Awaji Earthquake, National Research Institute for Earth Science and Disaster Prevention plan to construct the 3-D Full-Scale Earthquake Testing Facility. This will be the world's largest and strongest shaking table facility. This paper describes the outline of the project for this facility. This facility will be completed in early 2005. (author)

World new facilities for radioactive isotope beams

International Nuclear Information System (INIS)

Motobayashi, T.

2014-01-01

The use of unstable nuclei in the form of energetic beams for nuclear physics studies is now entering into a new era. 'New-generation' facilities are either in operation, under construction or being planned. They are designed to provide radioactive isotope (RI) beams with very high intensities over a wide range of nuclides. These facilities are expected to provide opportunities to study nuclear structure, astrophysical nuclear processes and nuclear matter with large proton-neutron imbalance in grate detail. This article reports on the current status of such new-generation RI-beam facilities around the world. In order to cover different energy domains and to meet various scientific demands, the designs of RI-beam facilities are of a wide variety. For example, RIBF in Japan, FAIR in Germany and FRIB in US are based on the fragmentation scheme for beams with energies of a few hundred MeV/nucleon to GeV/nucleon, whereas Spiral2 in France, SPES in Italy, HIE-ISOLDE in Switzerland/France, and the future facility EURISOL in Europe are based on the ISOL method, and aim at providing lower-energy RI beams. There are a many other projects including upgrades of existing facilities in the three continents, America, Asia and Europe

Influence of condensation on heat flux and pressure measurements in a detonation-based short-duration facility

Science.gov (United States)

Haase, S.; Olivier, H.

2017-10-01

Detonation-based short-duration facilities provide hot gas with very high stagnation pressures and temperatures. Due to the short testing time, complex and expensive cooling techniques of the facility walls are not needed. Therefore, they are attractive for economical experimental investigations of high-enthalpy flows such as the flow in a rocket engine. However, cold walls can provoke condensation of the hot combustion gas at the walls. This has already been observed in detonation tubes close behind the detonation wave, resulting in a loss of tube performance. A potential influence of condensation at the wall on the experimental results, like wall heat fluxes and static pressures, has not been considered so far. Therefore, in this study the occurrence of condensation and its influence on local heat flux and pressure measurements has been investigated in the nozzle test section of a short-duration rocket-engine simulation facility. This facility provides hot water vapor with stagnation pressures up to 150 bar and stagnation temperatures up to 3800 K. A simple method has been developed to detect liquid water at the wall without direct optical access to the flow. It is shown experimentally and theoretically that condensation has a remarkable influence on local measurement values. The experimental results indicate that for the elimination of these influences the nozzle wall has to be heated to a certain temperature level, which exclusively depends on the local static pressure.

Effect of maternal age on facility-based delivery: analysis of first-order births in 34 countries of sub-Saharan Africa using demographic and health survey data.

Science.gov (United States)

Dunlop, Catherine L; Benova, Lenka; Campbell, Oona

2018-04-13

Increasing access to skilled birth attendance, usually via childbirth in health facilities, is a key intervention to reduce maternal and perinatal mortality and morbidity. Yet, in some countries of sub-Saharan Africa, the uptake is Health Surveys from 34 sub-Saharan African countries were used to assess women's delivery locations. 72 772 women having their first birth in the 5 years preceding the surveys were included in the analysis. Proportions and 95% CIs of facility-based deliveries were estimated overall and by country. Multivariable logistic regression was used to calculate the odds of facility-based delivery for different maternal age groups (15-19, 20-24 and ≥25 years) for a pooled sample of all countries. 59.9% of women had a facility-based delivery for their first birth (95% CI 58.6 to 61.2), ranging from 19.4% in Chad to 96.6% in Rwanda. Compared with women aged 15-19 years, the adjusted odds of having a facility-based delivery for those aged 20-24 was 1.4 (95% CI 1.3 to 1.5, psub-Saharan Africa. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Simulation of facility operations and materials accounting for a combined reprocessing/MOX fuel fabrication facility

International Nuclear Information System (INIS)

Coulter, C.A.; Whiteson, R.; Zardecki, A.

1991-01-01

We are developing a computer model of facility operations and nuclear materials accounting for a facility that reprocesses spent fuel and fabricates mixed oxide (MOX) fuel rods and assemblies from the recovered uranium and plutonium. The model will be used to determine the effectiveness of various materials measurement strategies for the facility and, ultimately, of other facility safeguards functions as well. This portion of the facility consists of a spent fuel storage pond, fuel shear, dissolver, clarifier, three solvent-extraction stages with uranium-plutonium separation after the first stage, and product concentrators. In this facility area mixed oxide is formed into pellets, the pellets are loaded into fuel rods, and the fuel rods are fabricated into fuel assemblies. These two facility sections are connected by a MOX conversion line in which the uranium and plutonium solutions from reprocessing are converted to mixed oxide. The model of the intermediate MOX conversion line used in the model is based on a design provided by Mike Ehinger of Oak Ridge National Laboratory (private communication). An initial version of the simulation model has been developed for the entire MOX conversion and fuel fabrication sections of the reprocessing/MOX fuel fabrication facility, and this model has been used to obtain inventory difference variance estimates for those sections of the facility. A significant fraction of the data files for the fuel reprocessing section have been developed, but these data files are not yet complete enough to permit simulation of reprocessing operations in the facility. Accordingly, the discussion in the following sections is restricted to the MOX conversion and fuel fabrication lines. 3 tabs

Conceptual designs of near surface disposal facility for radioactive waste arising from the facilities using radioisotopes and research facilities for nuclear energy development and utilization

International Nuclear Information System (INIS)

Sakai, Akihiro; Yoshimori, Michiro; Okoshi, Minoru; Yamamoto, Tadatoshi; Abe, Masayoshi

2001-03-01

Various kinds of radioactive waste is generating from the utilization of radioisotopes in the field of science, technology, etc. and the utilization and development of nuclear energy. In order to promote the utilization of radionuclides and the research activities, it is necessary to treat and dispose of radioactive waste safely and economically. Japan Nuclear Cycle Development Institute (JNC), Japan Radioisotope Association (JRIA) and Japan Atomic Energy Research Institute (JAERI), which are the major waste generators in Japan in these fields, are promoting the technical investigations for treatment and disposal of the radioactive waste co-operately. Conceptual design of disposal facility is necessary to demonstrate the feasibility of waste disposal business and to determine the some conditions such as the area size of the disposal facility. Three institutes share the works to design disposal facility. Based on our research activities and experiences of waste disposal, JAERI implemented the designing of near surface disposal facilities, namely, simple earthen trench and concrete vaults. The designing was performed based on the following three assumed site conditions to cover the future site conditions: (1) Case 1 - Inland area with low groundwater level, (2) Case 2 - Inland area with high groundwater level, (3) Case 3 - Coastal area. The estimation of construction costs and the safety analysis were also performed based on the designing of facilities. The safety assessment results show that the safety for concrete vault type repository is ensured by adding low permeability soil layer, i.e. mixture of soil and bentonite, surrounding the vaults not depending on the site conditions. The safety assessment results for simple earthen trench also show that their safety is ensured not depending on the site conditions, if they are constructed above groundwater levels. The construction costs largely depend on the depth for excavation to build the repositories. (author)

Integral Monitored Retrievable Storage (MRS) Facility conceptual design report

International Nuclear Information System (INIS)

1985-09-01

The Basis for Design established the functional requirements and design criteria for an Integral Monitored Retrievable Storage (MRS) facility. The MRS Facility design, described in this report, is based on those requirements and includes all infrastructure, facilities, and equipment required to routinely receive, unload, prepare for storage, and store spent fuel (SF), high-level waste (HLW), and transuranic waste (TRU), and to decontaminate and return shipping casks received by both rail and truck. The facility is complete with all supporting facilities to make the MRS Facility a self-sufficient installation

FT-Raman spectroscopic analysis of Nd:YAG and Er,Cr:YSGG laser irradiated enamel for preventive purposes

Science.gov (United States)

Ana, P. A.; Kauffmann, C. M. F.; Bachmann, L.; Soares, L. E. S.; Martin, A. A.; Gomes, A. S. L.; Zezell, D. M.

2014-03-01

This study evaluated the effect of combining laser irradiation with fluoride on an enamel microstructure and demineralization by FT-Raman spectroscopy (FTRS). Eighty human enamel slabs were divided into eight groups: (G1) untreated; (G2) acidulated phosphate fluoride application (APF—1.23% F- for 4 min) (G3) Nd:YAG irradiation (84.9 J cm-2, 60 mJ/pulse) (G4) Nd:YAG + APF; (G5) APF + Nd:YAG; (G6) Er,Cr:YSGG irradiation (2.8 J cm-2, 12.5 mJ/pulse) (G7) Er,Cr:YSGG + APF; and (G8) APF + Er,Cr:YSGG. After treatment, the samples were submitted to a ten-day pH-cycling model. Chemical changes were determined on the slabs before and after treatment, and also after pH-cycling, by FTRS in the range 400-4000 cm-1. The inorganic bands at 440, 590, 870, 960, 1100 cm-1, and the organic bands at 1270, 1450, 1670, 2945 cm-1 were considered. Demineralization promoted reduction in organic contents; Nd:YAG laser irradiation promoted loss of carbonate and organic content, while Er,Cr:YSGG did not produce significant changes in the relative band intensities of organic and inorganic contents of the enamel. In lased samples, no effects caused by pH-cycling on enamel were observed. In conclusion, laser treatment and its association with fluoride can somehow interfere with the demineralization dynamics, reducing its effects over the enamel.

IFMIF [International Fusion Materials Irradiation Facility], an accelerator-based neutron source for fusion components irradiation testing: Materials testing capabilities

International Nuclear Information System (INIS)

Mann, F.M.

1988-08-01

The International Fusion Materials Irradiation Facility (IFMIF) is proposed as an advanced accelerator-based neutron source for high-flux irradiation testing of large-sized fusion reactor components. The facility would require only small extensions to existing accelerator and target technology originally developed for the Fusion Materials Irradiation Test (FMIT) facility. At the extended facility, neutrons would be produced by a 0.1-A beam of 35-MeV deuterons incident upon a liquid lithium target. The volume available for high-flux (>10/sup 15/ n/cm/sup 2/-s) testing in IFMITF would be over a liter, a factor of about three larger than in the FMIT facility. This is because the effective beam current of 35-MeV deuterons on target can be increased by a factor of ten to 1A or more. Such an increase can be accomplished by funneling beams of deuterium ions from the radio-frequency quadruple into a linear accelerator and by taking advantage of recent developments in accelerator technology. Multiple beams and large total current allow great variety in available testing. For example, multiple simultaneous experiments, and great flexibility in tailoring spatial distributions of flux and spectra can be achieved. 5 refs., 2 figs., 1 tab

Structural integrity assessment based on the HFR Petten neutron beam facilities

CERN Document Server

Ohms, C; Idsert, P V D

2002-01-01

Neutrons are becoming recognized as a valuable tool for structural-integrity assessment of industrial components and advanced materials development. Microstructure, texture and residual stress analyses are commonly performed by neutron diffraction and a joint CEN/ISO Pre-Standard for residual stress analysis is under development. Furthermore neutrons provide for defects analyses, i.e. precipitations, voids, pores and cracks, through small-angle neutron scattering (SANS) or radiography. At the High Flux Reactor, 12 beam tubes have been installed for the extraction of thermal neutrons for such applications. Two of them are equipped with neutron diffractometers for residual stress and structure determination and have been extensively used in the past. Several other facilities are currently being reactivated and upgraded. These include the SANS and radiography facilities as well as a powder diffractometer. This paper summarizes the main characteristics and current status of these facilities as well as recently in...

Facility effluent monitoring plan determinations for the 400 Area facilities

International Nuclear Information System (INIS)

Nickels, J.M.

1991-09-01

This Facility Effluent Monitoring Plan determination resulted from an evaluation conducted for the Westinghouse Hanford Company 400 Area facilities on the Hanford Site. The Facility Effluent Monitoring Plan determinations have been prepared in accordance with A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans. Two major Westinghouse Hanford Company facilities in the 400 Area were evaluated: the Fast Flux Test Facility and the Fuels Manufacturing and examination Facility. The determinations were prepared by Westinghouse Hanford Company. Of these two facilities, only the Fast Flux Test Facility will require a Facility Effluent Monitoring Plan. 7 refs., 5 figs., 4 tabs

Multi-site risk-based project planning, optimization, sequencing, & budgeting process and tool for the integrated facility disposition project

International Nuclear Information System (INIS)

Nelson, J.G.; Castillo, C.; Huntsman, J.; Killoy, S.; Lucek, H.; Marks, T.C.

2011-01-01

Faced with the Department of Energy (DOE) Complex Transformation, National Nuclear Security Administration (NNSA) was tasked with developing an integrated plan for the decommissioning of over 400 facilities and 300 environmental remediation units, as well as the many reconfiguration and modernization projects at the Oak Ridge National Laboratory (ORNL) and Y-12 Complex. Manual scheduling of remediation activities is time-consuming and inherently introduces bias of the scheduler or organization into the process. Clearly a well-defined process, quantitative risk-based tool was needed to develop an objective, unbiased baseline sequence and schedule with a sound technical foundation for the Integrated Facility Disposition Project (IFDP). Faced with limited available data, innovation was needed to extrapolate intelligent relative data for key risk parameters based on known data elements. The IFDP Supermodel was customized and expanded to provide this capability for conceptual planning of diverse project portfolios and multiple sites. (author)

The earthing system of the PRIMA Neutral Beam Test Facility based on the Mesh Common Bonding Network topology

International Nuclear Information System (INIS)

Pomaro, Nicola; Boldrin, Marco; Lazzaro, Gabriele

2015-01-01

Highlights: • We designed a high performance earthing system for the ITER Neutral Beam Test Facility. • The system is based on the Mesh Common Bonded Network topology. • Careful bonding of all metallic structures allowed to obtain a well meshed system. • Special care was dedicated to improve EMC performance of critical areas like control rooms. • The facility experimental results will be representative also of the ITER situation. - Abstract: PRIMA is a large experimental facility under realization in Padova, aimed at developing and testing the Neutral Beam Injectors for ITER. The operation of these devices involves high RF power and voltage up to 1 MV. Frequent and high voltage electrical breakdowns inside the beam sources occur regularly. The presence of a distributed carefully optimized earthing system is of paramount importance to achieve a satisfying disturbances immunity for equipment and diagnostics. The paper describes the design and the realization of the earthing system of the PRIMA facility, which is based on the MESH-Common Bonding Network (MESH-CBN) topology, as recommended by IEC and IEEE standards for installations with high levels of Electromagnetic Interferences (EMI). The principles of the MESH-CBN approach were adapted to the PRIMA layout, which is composed by several buildings, that are independent for seismic and architectural reasons, but are linked by many electrical conduits and hydraulic pipelines. The availability of huge foundations, with a large number of poles and pillars, was taken into account; building parts dedicated to host control rooms and sensitive equipment were treated with particular care. Moreover, the lightning protection system was integrated and harmonized with the earthing system.

The earthing system of the PRIMA Neutral Beam Test Facility based on the Mesh Common Bonding Network topology

Energy Technology Data Exchange (ETDEWEB)

Pomaro, Nicola, E-mail: nicola.pomaro@igi.cnr.it; Boldrin, Marco; Lazzaro, Gabriele

2015-10-15

Highlights: • We designed a high performance earthing system for the ITER Neutral Beam Test Facility. • The system is based on the Mesh Common Bonded Network topology. • Careful bonding of all metallic structures allowed to obtain a well meshed system. • Special care was dedicated to improve EMC performance of critical areas like control rooms. • The facility experimental results will be representative also of the ITER situation. - Abstract: PRIMA is a large experimental facility under realization in Padova, aimed at developing and testing the Neutral Beam Injectors for ITER. The operation of these devices involves high RF power and voltage up to 1 MV. Frequent and high voltage electrical breakdowns inside the beam sources occur regularly. The presence of a distributed carefully optimized earthing system is of paramount importance to achieve a satisfying disturbances immunity for equipment and diagnostics. The paper describes the design and the realization of the earthing system of the PRIMA facility, which is based on the MESH-Common Bonding Network (MESH-CBN) topology, as recommended by IEC and IEEE standards for installations with high levels of Electromagnetic Interferences (EMI). The principles of the MESH-CBN approach were adapted to the PRIMA layout, which is composed by several buildings, that are independent for seismic and architectural reasons, but are linked by many electrical conduits and hydraulic pipelines. The availability of huge foundations, with a large number of poles and pillars, was taken into account; building parts dedicated to host control rooms and sensitive equipment were treated with particular care. Moreover, the lightning protection system was integrated and harmonized with the earthing system.

Performance Improvement of Shunt Active Power Filter With Dual Parallel Topology

DEFF Research Database (Denmark)

Asiminoaei, Lucian; Lascu, Cristian; Blaabjerg, Frede

2007-01-01

loop and the other is in a feedforward loop for harmonic compensation. Thus, both active power filters bring their own characteristic advantages, i.e., the feedback filter improves the steady-state performance of the harmonic mitigation and the feedforward filter improves the dynamic response. Another......This paper describes the control and parallel operation of two active power filters (APFs). Possible parallel operation situations of two APFs are investigated, and then the proposed topology is analyzed. The filters are coupled in a combined topology in which one filter is connected in a feedback...

Argonne's new Wakefield Test Facility

International Nuclear Information System (INIS)

Simpson, J.D.

1992-01-01

The first phase of a high current, short bunch length electron beam research facility, the AWA, is near completion at Argonne. At the heart of the facility is a photocathode based electron gun and accelerating sections designed to deliver 20 MeV pulses with up to 100 nC per pulse and with pulse lengths of approximately 15 ps (fw). Using a technique similar to that originated at Argonne's AATF facility, a separate weak probe pulse can be generated and used to diagnose wake effects produced by the intense pulses. Initial planned experiments include studies of plasma wakefields and dielectric wakefield devices, and expect to demonstrate large, useful accelerating gradients (> 100 MeV/m). Later phases of the facility will increase the drive bunch energy to more than 100 MeV to enable acceleration experiments up to the GeV range. Specifications, design details, and commissioning progress are presented

On exposure management of workers in nuclear reactor facilities for test and in nuclear reactor facilities in research and development stage in fiscal 1993

International Nuclear Information System (INIS)

1994-01-01

The Law of Regulation on Nuclear Reactor requires the operators of nuclear reactors that the exposure dose of workers engaged in work for nuclear reactors should not exceed the limits specified in official notices that are issued based on the Law. The present article summarizes the contents of the Report on Radiation Management in 1993 submitted by the operators of nuclear reactor facilities for test and those of nuclear reactor facilities in research and development stage based on the Law, and the Report on Management of Exposure Dose of Workers submitted by them based on administrative notices. The reports demonstrate that the the exposure of workers was below the permissible exposure dose in 1993 in all nuclear reactor facilities. The article presents data on the distribution of exposure dose among workers in all facilities with a nuclear reactor for test, and data on personal exposure of employees and non-employees and overall exposure of all workers in the facilities of JAERI and PNC. (J.P.N.)

Rancang Bangun STIKI Class Facilities E-Complaint

OpenAIRE

Ni Kadek Ariasih; I Made Gede Sri Artha

2017-01-01

STMIK STIKOM Indonesia is one of the institutions in the field of computer-based education. In order to support the effectiveness of the implementation of teaching and learning activities that take place, it is need a service that support the availability of adequate class facilities and complaints services if there are constraints on facilities in the classroom. So far, the management of complaints complaints against classroom facilities or in the labarotorium which is handled by the Househo...

A New Synchronous Reference Frame-Based Method for Single-Phase Shunt Active Power Filters

DEFF Research Database (Denmark)

Monfared, Mohammad; Golestan, Saeed; Guerrero, Josep M.

2013-01-01

This paper deals with the design of a novel method in the synchronous reference frame (SRF) to extract the reference compensating current for single-phase shunt active power filters (APFs). Unlike previous works in the SRF, the proposed method has an innovative feature that it does not need...... the fictitious current signal. Frequency-independent operation, accurate reference current extraction and relatively fast transient response are other key features of the presented strategy. The effectiveness of the proposed method is investigated by means of detailed mathematical analysis. The results confirm...

A Slicing Tree Representation and QCP-Model-Based Heuristic Algorithm for the Unequal-Area Block Facility Layout Problem

Directory of Open Access Journals (Sweden)

Mei-Shiang Chang

2013-01-01

Full Text Available The facility layout problem is a typical combinational optimization problem. In this research, a slicing tree representation and a quadratically constrained program model are combined with harmony search to develop a heuristic method for solving the unequal-area block layout problem. Because of characteristics of slicing tree structure, we propose a regional structure of harmony memory to memorize facility layout solutions and two kinds of harmony improvisation to enhance global search ability of the proposed heuristic method. The proposed harmony search based heuristic is tested on 10 well-known unequal-area facility layout problems from the literature. The results are compared with the previously best-known solutions obtained by genetic algorithm, tabu search, and ant system as well as exact methods. For problems O7, O9, vC10Ra, M11*, and Nug12, new best solutions are found. For other problems, the proposed approach can find solutions that are very similar to previous best-known solutions.

Status of the SXFEL Facility

Directory of Open Access Journals (Sweden)

Zhentang Zhao

2017-06-01

Full Text Available The Shanghai soft X-ray Free-Electron Laser facility (SXFEL is being developed in two steps; the SXFEL test facility (SXFEL-TF, and the SXFEL user facility (SXFEL-UF. The SXFEL-TF is a critical development step towards the construction a soft X-ray FEL user facility in China, and is under commissioning at the Shanghai Synchrotron Radiation Facility (SSRF campus. The test facility is going to generate 8.8 nm FEL radiation using an 840 MeV electron linac passing through the two-stage cascaded HGHG-HGHG or EEHG-HGHG (high-gain harmonic generation, echo-enabled harmonic generation scheme. The construction of the SXFEL-TF started at the end of 2014. Its accelerator tunnel and klystron gallery were ready for equipment installation in April 2016, and the installation of the SXFEL-TF linac and radiator undulators were completed by the end of 2016. In the meantime, the SXFEL-UF, with a designated wavelength in the water window region, began construction in November 2016. This was based on upgrading the linac energy to 1.5 GeV, and the building of a second undulator line and five experimental end-stations. Construction status and the future plans of the SXFEL are reported in this paper.

Fuel conditioning facility material accountancy

International Nuclear Information System (INIS)

Yacout, A.M.; Bucher, R.G.; Orechwa, Y.

1995-01-01

The operation of the Fuel conditioning Facility (FCF) is based on the electrometallurgical processing of spent metallic reactor fuel. It differs significantly, therefore, from traditional PUREX process facilities in both processing technology and safeguards implications. For example, the fissile material is processed in FCF only in batches and is transferred within the facility only as solid, well-characterized items; there are no liquid steams containing fissile material within the facility, nor entering or leaving the facility. The analysis of a single batch lends itself also to an analytical relationship between the safeguards criteria, such as alarm limit, detection probability, and maximum significant amount of fissile material, and the accounting system's performance, as it is reflected in the variance associated with the estimate of the inventory difference. This relation, together with the sensitivity of the inventory difference to the uncertainties in the measurements, allows a thorough evaluation of the power of the accounting system. The system for the accountancy of the fissile material in the FCF has two main components: a system to gather and store information during the operation of the facility, and a system to interpret this information with regard to meeting safeguards criteria. These are described and the precision of the inventory closure over one batch evaluated

Surrogate Plant Data Base : Volume 3. Appendix D : Facilities Planning Data ; Operating Manpower, Manufacturing Budgets and Pre-Production Launch ...

Science.gov (United States)

1983-05-01

This four volume report consists of a data base describing "surrogate" automobile and truck manufacturing plants developed as part of a methodology for evaluating capital investment requirements in new manufacturing facilities to build new fleets of ...

Wound center facility billing: A retrospective analysis of time, wound size, and acuity scoring for determining facility level of service.

Science.gov (United States)

Fife, Caroline E; Walker, David; Farrow, Wade; Otto, Gordon

2007-01-01

Outpatient wound center facility reimbursement for Medicare beneficiaries can be a challenge to determine and obtain. To compare methods of calculating facility service levels for outpatient wound centers and to demonstrate the advantages of an acuity-based billing system (one that incorporates components of facility work that is non-reimbursable by procedure codes and that represents an activity-based costing approach to medical billing), a retrospective study of 5,098 patient encounters contained in a wound care-specific electronic medical record database was conducted. Approximately 500 patient visits to the outpatient wound center of a Texas regional hospital between April 2003 and November 2004 were categorized by service level in documentation and facility management software. Visits previously billed using a time-based system were compared to the Centers for Medicare and Medicaid Services' proposed three-tiered wound size-based system. The time-based system also was compared to an acuity-based scoring system. The Pearson correlation coefficient between billed level of service by time and estimated level of service by acuity was 0.442 and the majority of follow-up visits were billed as Level 3 and above (on a time level of 1 to 5) , confirming that time is not a surrogate for actual work performed. Wound size also was found to be unrelated to service level (Pearson correlation = 0.017) and 97% of wound areas were billings than extremes; no other method produced this distribution. Hospital-based outpatient wound centers should develop, review, and refine acuity score-based models on which to determine billed level of service.

In vitro study of morphological and chemical modification threshold of bovine dental enamel irradiated by the holmium laser

International Nuclear Information System (INIS)

Eduardo, Patricia Lerro de Paula

2001-01-01

The aim of this study is to investigate the Ho:YLF laser effects on the dental enamel surface with regards to its morphology, thermal variations during its irradiation in the pulp chamber and its increased resistance to demineralization through quantitative analysis of calcium and phosphorous atoms reactive concentrations in samples. Twenty samples of bovine enamel were used and divided in four groups: control - acidulated phosphate fluoride (APF) application followed by demineralization treatment with lactic acid; irradiation with Ho:YLF laser (100 J/cm 2 ) followed by APF topic application and demineralization treatment with lactic acid; irradiation with Ho:YLF laser (350 J/cm 2 ) followed by APF topic application and demineralization treatment with lactic acid: and irradiation with Ho:YLF laser ( 450 J/cm 2 ) followed by APF topic application and demineralization treatment with lactic acid. Ali samples were quantified according to their calcium and phosphorous atoms relative concentrations before and after the treatments above. X-Ray fluorescence spectrochemical analysis and scanning electron microscopy were carried out. It was observed an increase on the calcium and phosphorous atoms concentration ratio and therefore the enamel demineralization reduction as a result of the lactic acid treatment in the samples irradiated with the holmium laser followed by the APF application. In order to evaluate the feasibility of this study for clinical purposes, morphological changes caused by the holmium laser irradiation were analyzed. Such modifications were characterized by melted and re-solidified regions of the enamel with consequent changes on its permeability and solubility. Temperature changes of ten human pre-molars teeth irradiated with 350 J/cm 2 and 450 J/cm 2 were also monitored in the pulp chamber in real time. Temperature increases over 4,20 C did not occur. The results obtained from this study along with the results from previous researches developed at

In vitro study of morphological and chemical modification threshold of bovine dental enamel irradiated by the holmium laser; Estudo in vitro das alteracoes morfologicas e quimicas do esmalte dental bovino irradiado pelo laser de holmio

Energy Technology Data Exchange (ETDEWEB)

Eduardo, Patricia Lerro de Paula

2001-07-01

The aim of this study is to investigate the Ho:YLF laser effects on the dental enamel surface with regards to its morphology, thermal variations during its irradiation in the pulp chamber and its increased resistance to demineralization through quantitative analysis of calcium and phosphorous atoms reactive concentrations in samples. Twenty samples of bovine enamel were used and divided in four groups: control - acidulated phosphate fluoride (APF) application followed by demineralization treatment with lactic acid; irradiation with Ho:YLF laser (100 J/cm{sup 2}) followed by APF topic application and demineralization treatment with lactic acid; irradiation with Ho:YLF laser (350 J/cm{sup 2}) followed by APF topic application and demineralization treatment with lactic acid: and irradiation with Ho:YLF laser ( 450 J/cm{sup 2}) followed by APF topic application and demineralization treatment with lactic acid. Ali samples were quantified according to their calcium and phosphorous atoms relative concentrations before and after the treatments above. X-Ray fluorescence spectrochemical analysis and scanning electron microscopy were carried out. It was observed an increase on the calcium and phosphorous atoms concentration ratio and therefore the enamel demineralization reduction as a result of the lactic acid treatment in the samples irradiated with the holmium laser followed by the APF application. In order to evaluate the feasibility of this study for clinical purposes, morphological changes caused by the holmium laser irradiation were analyzed. Such modifications were characterized by melted and re-solidified regions of the enamel with consequent changes on its permeability and solubility. Temperature changes of ten human pre-molars teeth irradiated with 350 J/cm{sup 2} and 450 J/cm{sup 2} were also monitored in the pulp chamber in real time. Temperature increases over 4,20 C did not occur. The results obtained from this study along with the results from previous

On exposure of workers in nuclear reactor facilities for test and in nuclear reactor facilities in research and development stage in fiscal 1988

International Nuclear Information System (INIS)

1989-01-01

The Law for Regulation on Nuclear Reactor requires the operators of nuclear reactors that the exposure dose of workers engaged in work for nuclear reactors should not exceed the limits specified in official notices that are issued based on the Law. The present article summarizes the contents of the Report on Radiation Management in 1988 submitted by the operators of nuclear reactor facilities for test and those of nuclear reactor facilities in research and development stage based on the Law, and the Report on Management of Exposure Dose of Workers submitted by them based on administrative notices. The reports demonstrate that the exposure of workers was below the permissible exposure dose in 1988 in all nuclear reactor facilities. The article presents data on the distribution of exposure dose among workers in all facilities with a nuclear reactor for test, and data on personal exposure of employees and non-employees and overall exposure of all workers in the facilities of Japan Atomic Energy Research Institute and Power Reactor and Nuclear Fuel Development Corporation. (N.K.)

Health and Safety Management for Small-scale Methane Fermentation Facilities

Science.gov (United States)

Yamaoka, Masaru; Yuyama, Yoshito; Nakamura, Masato; Oritate, Fumiko

In this study, we considered health and safety management for small-scale methane fermentation facilities that treat 2-5 ton of biomass daily based on several years operation experience with an approximate capacity of 5 t·d-1. We also took account of existing knowledge, related laws and regulations. There are no qualifications or licenses required for management and operation of small-scale methane fermentation facilities, even though rural sewerage facilities with a relative similar function are required to obtain a legitimate license. Therefore, there are wide variations in health and safety consciousness of the operators of small-scale methane fermentation facilities. The industrial safety and health laws are not applied to the operation of small-scale methane fermentation facilities. However, in order to safely operate a small-scale methane fermentation facility, the occupational safety and health management system that the law recommends should be applied. The aims of this paper are to clarify the risk factors in small-scale methane fermentation facilities and encourage planning, design and operation of facilities based on health and safety management.

Perceived risk impacts from siting hazardous waste facilities

International Nuclear Information System (INIS)

Hemphill, R.C.; Edwards, B.K.; Bassett, G.W. Jr.

1992-01-01

This paper describes methods for evaluating perception-based economic impacts resulting from siting hazardous waste facilities. Socioeconomic impact analysis has devoted increasing attention to the potential implications of changed public perceptions of risk due to an activity or situation. This contrasts with traditional socioecconomic impact analysis, which has been limited to measuring direct and indirect consequences of activities, e.g., the employment effects of placing a military base in a specified location. Approaches to estimating economic impacts due to changes in public perceptions are ex ante or ex post. The former predict impacts prior to the construction and operation of a facility, while the later is based on impacts that become evident only when the facility is up and running. The theoretical foundations and practical requirements for demonstrating impacts, resulting from the siting of a hazardous facility are described. The theoretical rationale supporting the study of perceived risk research is presented along with discussion of problems that arise in demonstrating the existence and measuring the quantitative importance of economic impacts due to changes in perceived risk. The high-level nuclear waste facility being considered in Nevada is presented as an example in which there is potential for impacts, but where the link between perceived risk and economic conditions has not yet been developed

Perceived risk impacts from siting hazardous waste facilities

International Nuclear Information System (INIS)

Hemphill, R.C.; Edwards, B.K.; Bassett, G.W. Jr.

1992-01-01

This paper describes methods for evaluating perception-based economic impacts resulting from siting hazardous waste facilities. Socioeconomic impact analysis has devoted increasing attention to the potential implications of changed public perceptions of risk due to an activity or situation. This contrasts with traditional socioeconomic impact analysis, which has been limited to measuring direct and indirect consequences of activities, e.g., the employment effects of placing a military base in a specified location. Approaches to estimating economic impacts due to changes in public perceptions are ex ante or ex post. The former predict impacts prior to the construction and operation of a facility, while the later is based on impacts that become evident only when the facility is up and running. The theoretical foundations and practical requirements for demonstrating impacts resulting from the siting of a hazardous facility are described. The theoretical rationale supporting the study of perceived risk research is presented along with discussion of problems that arise in demonstrating the existence and measuring the quantitative importance of economic impacts due to changes in perceived risk. The high-level nuclear waste facility being considered in Nevada is presented as an example in which there is potential for impacts, but where the link between perceived risk and economic conditions has not yet been developed

Adherence to evidence based care practices for childbirth before and after a quality improvement intervention in health facilities of Rajasthan, India.

Science.gov (United States)

Iyengar, Kirti; Jain, Motilal; Thomas, Sunil; Dashora, Kalpana; Liu, William; Saini, Paramsukh; Dattatreya, Rajesh; Parker, Indrani; Iyengar, Sharad

2014-08-13

After the launch of Janani Suraksha Yojana, a conditional cash transfer scheme in India, the proportion of women giving birth in institutions has rapidly increased. However, there are important gaps in quality of childbirth services during institutional deliveries. The aim of this intervention was to improve the quality of childbirth services in selected high caseload public health facilities of 10 districts of Rajasthan. This intervention titled "Parijaat" was designed by Action Research & Training for Health, in partnership with the state government and United Nations Population Fund. The intervention was carried out in 44 public health facilities in 10 districts of Rajasthan, India. These included district hospitals (9), community health centres (32) and primary health centres (3). The main intervention was orientation training of doctors and program managers and regular visits to facilities involving assessment, feedback, training and action. The adherence to evidence based practices before, during and after this intervention were measured using structured checklists and scoring sheets. Main outcome measures included changes in practices during labour, delivery or immediate postpartum period. Use of several unnecessary or harmful practices reduced significantly. Most importantly, proportion of facilities using routine augmentation of labour reduced (p = 0), episiotomy for primigravidas (p = 0.0003), fundal pressure (p = 0.0003), and routine suction of newborns (0 = 0.0005). Among the beneficial practices, use of oxytocin after delivery increased (p = 0.0001) and the practice of listening foetal heart sounds during labour (p = 0.0001). Some practices did not show any improvements, such as dorsal position for delivery, use of partograph, and hand-washing. An intervention based on repeated facility visits combined with actions at the level of decision makers can lead to substantial improvements in quality of childbirth practices at health facilities.

Safety of magnetic fusion facilities: Volume 2, Guidance

International Nuclear Information System (INIS)

1995-01-01

This document provides guidance for the implementation of the requirements identified in Vol. 1 of this Standard. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While Vol. 1 is generally applicable in that requirements there apply to a wide range of fusion facilities, this volume is concerned mainly with large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This volume is oriented toward regulation in the Department of Energy (DOE) environment

Potential applications of artificial intelligence in computer-based management systems for mixed waste incinerator facility operation

International Nuclear Information System (INIS)

Rivera, A.L.; Singh, S.P.N.; Ferrada, J.J.

1991-01-01

The Department of Energy/Oak Ridge Field Office (DOE/OR) operates a mixed waste incinerator facility at the Oak Ridge K-25 Site, designed for the thermal treatment of incinerable liquid, sludge, and solid waste regulated under the Toxic Substances Control Act (TSCA) and the Resource Conversion and Recovery Act (RCRA). Operation of the TSCA Incinerator is highly constrained as a result of the regulatory, institutional, technical, and resource availability requirements. This presents an opportunity for applying computer technology as a technical resource for mixed waste incinerator operation to facilitate promoting and sustaining a continuous performance improvement process while demonstrating compliance. This paper describes mixed waste incinerator facility performance-oriented tasks that could be assisted by Artificial Intelligence (AI) and the requirements for AI tools that would implement these algorithms in a computer-based system. 4 figs., 1 tab

Estimating Fire Risks at Industrial Nuclear Facilities

International Nuclear Information System (INIS)

Coutts, D.A.

1999-01-01

The Savannah River Site (SRS) has a wide variety of nuclear production facilities that include chemical processing facilities, machine shops, production reactors, and laboratories. Current safety documentation must be maintained for the nuclear facilities at SRS. Fire Risk Analyses (FRAs) are used to support the safety documentation basis. These FRAs present the frequency that specified radiological and chemical consequences will be exceeded. The consequence values are based on mechanistic models assuming specific fire protection features fail to function as designed

Measurement of photoneutron spectrum at Pohang Neutron Facility

Energy Technology Data Exchange (ETDEWEB)

Kim, G.N.; Kovalchuk, V.; Lee, Y.S.; Skoy, V.; Cho, M.H.; Ko, I.S.; Namkung, W. [POSTECH, Pohang Accelerator Laboratory, Pohang, Kyungbuk (Korea)

2001-03-01

Pohang Neutron Facility, which is the pulsed neutron facility based on the 100-MeV electron linear accelerator, was constructed for nuclear data production in Korea. The Pohang Neutron Facility consists of an electron linear accelerator, a water-cooled Ta target with a water moderator and a time-of-flight path with an 11 m length. The neutron energy spectra are measured for different water levels inside the moderator and compared with the MCNP calculation. The optimum size of the water moderator is determined on the base of this result. The time dependent spectra of neutrons in the water moderator are investigated with the MCNP calculation. (author)

Research of Active Power Filter Modeling with Grid Impedance in Feedback Linearization and Quasi-Sliding Mode Control

Directory of Open Access Journals (Sweden)

Zeyu Shi

2017-01-01

Full Text Available Active power filter (APF is the most popular device in regulating power quality issues. Currently, most literatures ignored the impact of grid impedance and assumed the load voltage is ideal, which had not described the system accurately. In addition, the controllers applied PI control; thus it is hard to improve the compensation quality. This paper establishes a precise model which consists of APF, load, and grid impedance. The Bode diagram of traditional simplified model is obviously different with complete model, which means the descriptions of the system based on the traditional simplified model are inaccurate and incomplete. And then design exact feedback linearization and quasi-sliding mode control (FBL-QSMC is based on precise model in inner current loop. The system performances in different parameters are analyzed and dynamic performance of proposed algorithm is compared with traditional PI control algorithm. At last, simulations are taken in three cases to verify the performance of proposed control algorithm. The results proved that the proposed feedback linearization and quasi-sliding mode control algorithm has fast response and robustness; the compensation performance is superior to PI control obviously, which also means the complete modeling and proposed control algorithm are correct.

Advanced facilities for radiochemistry at Harwell

International Nuclear Information System (INIS)

1985-01-01

The leaflets in this folder describe the latest addition to Harwell's active handling capability. This is a high level alpha, beta, gamma facility designed specifically for undertaking chemical research and development work. It is based on using high integrity containment boxes which are housed in concrete shielded enclosures. The active boxes can be removed and transferred remotely to a support area where they, and any associated equipment, can be decontaminated and serviced whilst a new fully commissioned box can be readily brought into service. The facility fulfills the principle of ALARA and is sufficiently flexible to accommodate a wide range of active handling requirements. It is supported by a suite of medium active handling cells, radiochemical laboratories and, as necessary, facilities of other scientific and engineering disciplines. The leaflets are: report on conceptual aspects; Techsheet 'Remote handling facility - Salient information'; Techsheet 'Project capabilities'; and 4 sheets of diagrams showing details of the facility. (U.K.)

Facility/equipment performance evaluation using microcomputer simulation analysis

International Nuclear Information System (INIS)

Chockie, A.D.; Hostick, C.J.

1985-08-01

A computer simulation analysis model was developed at the Pacific Northwest Laboratory to assist in assuring the adequacy of the Monitored Retrievable Storage facility design to meet the specified spent nuclear fuel throughput requirements. The microcomputer-based model was applied to the analysis of material flow, equipment capability and facility layout. The simulation analysis evaluated uncertainties concerning both facility throughput requirements and process duration times as part of the development of a comprehensive estimate of facility performance. The evaluations provided feedback into the design review task to identify areas where design modifications should be considered

A sensitive DNA biosensor based on a facile sulfamide coupling reaction for capture probe immobilization

International Nuclear Information System (INIS)

Wang, Qingxiang; Ding, Yingtao; Gao, Feng; Jiang, Shulian; Zhang, Bin; Ni, Jiancong; Gao, Fei

2013-01-01

Graphical abstract: A novel DNA biosensor was fabricated through a facile sulfamide coupling reaction between probe DNA and the sulfonic dye of 1-amino-2-naphthol-4-sulfonic acid that electrodeposited on a glassy carbon electrode. -- Highlights: •A versatile sulfonic dye of ANS was electrodeposited on a GCE. •A DNA biosensor was fabricated based on a facile sulfamide coupling reaction. •High probe DNA density of 3.18 × 10 13 strands cm −2 was determined. •A wide linear range and a low detection limit were obtained. -- Abstract: A novel DNA biosensor was fabricated through a facile sulfamide coupling reaction. First, the versatile sulfonic dye molecule of 1-amino-2-naphthol-4-sulfonate (AN-SO 3 − ) was electrodeposited on the surface of a glassy carbon electrode (GCE) to form a steady and ordered AN-SO 3 − layer. Then the amino-terminated capture probe was covalently grafted to the surface of SO 3 − -AN deposited GCE through the sulfamide coupling reaction between the amino groups in the probe DNA and the sulfonic groups in the AN-SO 3 − . The step-by-step modification process was characterized by electrochemistry and attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy. Using Ru(NH 3 ) 6 3+ as probe, the probe density and the hybridization efficiency of the biosensor were determined to be 3.18 × 10 13 strands cm −2 and 86.5%, respectively. The hybridization performance of the biosensor was examined by differential pulse voltammetry using Co(phen) 3 3+/2+ (phen = 1,10-phenanthroline) as the indicator. The selectivity experiments showed that the biosensor presented distinguishable response after hybridization with the three-base mismatched, non-complementary and complementary sequences. Under the optimal conditions, the oxidation peak currents of Co(phen) 3 3+/2+ increased linearly with the logarithm values of the concentration of the complementary sequences in the range from 1.0 × 10 −13 M to 1.0 × 10 −8 M with

Earthquake damage to underground facilities

International Nuclear Information System (INIS)

Pratt, H.R.; Stephenson, D.E.; Zandt, G.; Bouchon, M.; Hustrulid, W.A.

1980-01-01

In order to assess the seismic risk for an underground facility, a data base was established and analyzed to evaluate the potential for seismic disturbance. Substantial damage to underground facilities is usually the result of displacements primarily along pre-existing faults and fractures, or at the surface entrance to these facilities. Evidence of this comes from both earthquakes and large explosions. Therefore, the displacement due to earthquakes as a function of depth is important in the evaluation of the hazard to underground facilities. To evaluate potential displacements due to seismic effects of block motions along pre-existing or induced fractures, the displacement fields surrounding two types of faults were investigated. Analytical models were used to determine relative displacements of shafts and near-surface displacement of large rock masses. Numerical methods were used to determine the displacement fields associated with pure strike-slip and vertical normal faults. Results are presented as displacements for various fault lengths as a function of depth and distance. This provides input to determine potential displacements in terms of depth and distance for underground facilities, important for assessing potential sites and design parameters

Design of GMP compliance radiopharmaceutical production facility in MINT

International Nuclear Information System (INIS)

Anwar Abd Rahman; Shaharum Ramli; M Rizal Mamat Ibrahim; Rosli Darmawan; Yusof Azuddin Ali; Jusnan Hashim

2005-01-01

In 1985, MINT built the only radiopharmaceutical production facility in Malaysia. The facility was designed based on IAEA (International Atomic Energy Agency) standard guidelines which provide radiation safety to the staff and the surrounding environment from radioactive contamination. Since 1999, BPFK (Biro Pengawalan Farmaseutikal Kebangsaan) has used the guidelines from Pharmaceutical Inspection Convention Scheme (PICS) to meet the requirements of the Good Manufacturing Practice (GMP) for Pharmaceutical Products. In the guidelines, the pharmaceutical production facility shall be designed based on clean room environment. In order to design a radiopharmaceutical production facility, it is important to combine the concept of radiation safety and clean room to ensure that both requirements from GMP and IAEA are met. The design requirement is necessary to set up a complete radiopharmaceutical production facility, which is safe, has high production quality and complies with the Malaysian and International standards. (Author)

A facile nanoaggregation strategy for oral delivery of hydrophobic drugs by utilizing acid-base neutralization reactions

International Nuclear Information System (INIS)

Chen Huabing; Wan Jiangling; Wang Yirui; Mou Dongsheng; Liu Hongbin; Xu Huibi; Yang Xiangliang

2008-01-01

Nanonization strategies have been used to enhance the oral availability of numerous drugs that are poorly soluble in water. Exploring a facile nanonization strategy with highly practical potential is an attractive focus. Here, we report a novel facile nanoaggregation strategy for constructing drug nanoparticles of poorly soluble drugs with pH-dependent solubility by utilizing acid-base neutralization in aqueous solution, thus facilitating the exploration of nanonization in oral delivery for general applicability. We demonstrate that hydrophobic itraconazole dissolved in acid solution formed a growing core and aggregated into nanoparticles in the presence of stabilizers. The nanoparticles, with an average diameter of 279.3 nm and polydispersity index of 0.116, showed a higher dissolution rate when compared with the marketed formulation; the average dissolution was about 91.3%. The in vivo pharmacokinetic studies revealed that the nanoparticles had a rapid absorption and enhanced oral availability. The diet state also showed insignificant impact on the absorption of itraconazole from nanoparticles. This nanoaggregation strategy is a promising nanonization method with a facile process and avoidance of toxic organic solvents for oral delivery of poorly soluble drugs with pH-dependent solubility and reveals a highly practical potential in the pharmaceutical and chemical industries

Physics Detector Simulation Facility (PDSF) architecture/utilization

International Nuclear Information System (INIS)

Scipioni, B.

1993-05-01

The current systems architecture for the SSCL's Physics Detector Simulation Facility (PDSF) is presented. Systems analysis data is presented and discussed. In particular, these data disclose the effectiveness of utilization of the facility for meeting the needs of physics computing, especially as concerns parallel architecture and processing. Detailed design plans for the highly networked, symmetric, parallel, UNIX workstation-based facility are given and discussed in light of the design philosophy. Included are network, CPU, disk, router, concentrator, tape, user and job capacities and throughput

Dance Facilities.

Science.gov (United States)

Ashton, Dudley, Ed.; Irey, Charlotte, Ed.

This booklet represents an effort to assist teachers and administrators in the professional planning of dance facilities and equipment. Three chapters present the history of dance facilities, provide recommended dance facilities and equipment, and offer some adaptations of dance facilities and equipment, for elementary, secondary and college level…

Maintenance, repair and operation (MRO) of shutdown facilities

International Nuclear Information System (INIS)

Kenny, S.

2006-01-01

What level of maintenance does one apply to a shutdown facility? Well it depends on who you ask. Operations staff sees facilities that have completed their useful life cycle as a cost drain while Decommissioning staff sees this as the start of a new life cycle. Based on the decommissioning plan for the particular facility the building could complete another full life cycle while under decommissioning whether it is in storage with surveillance mode or under active decommissioning. This paper will explore how you maintain a facility and systems for many years after its useful life until final decommissioning is completed. When a building is declared redundant, who looks after it until the final decommissioning end state is achieved? At the AECL, Chalk River Labs site the safe shutdown and turnover process is one key element that initiates the decommissioning process. The real trick is orchestrating maintenance, repair and operation plans for a facility that has been poorly invested in during its last years of useful life cycle. To add to that usually shutdowns are prolonged for many years beyond the expected turnover period. During this presentation I will cover what AECL is doing to ensure that the facilities are maintained in a proper state until final decommissioning can be completed. All facilities or systems travel through the same life cycle, design, construction, commissioning, operation, shutdown and demolition. As we all know, nuclear facilities add one more interesting twist to this life cycle called Decommissioning that lands between shutdown and demolition. As a facility nears the shutdown phase, operations staff loose interest in the facility and stop investing in upgrades, repairs and maintenance but continue to invest and focus on maximizing operations. Facility maintenance standards produced by the International Facility Maintenance Association (IFMA) based on a survey done every year state that 2.2% of the total operating costs for the site should be

Development of a Medical Cyclotron Production Facility

Science.gov (United States)

Allen, Danny R.

2003-08-01

Development of a Cyclotron manufacturing facility begins with a business plan. Geographics, the size and activity of the medical community, the growth potential of the modality being served, and other business connections are all considered. This business used the customer base established by NuTech, Inc., an independent centralized nuclear pharmacy founded by Danny Allen. With two pharmacies in operation in Tyler and College Station and a customer base of 47 hospitals and clinics the existing delivery system and pharmacist staff is used for the cyclotron facility. We then added cyclotron products to contracts with these customers to guarantee a supply. We partnered with a company in the process of developing PET imaging centers. We then built an independent imaging center attached to the cyclotron facility to allow for the use of short-lived isotopes.

Development of a Medical Cyclotron Production Facility

International Nuclear Information System (INIS)

Allen, Danny R.

2003-01-01

Development of a Cyclotron manufacturing facility begins with a business plan. Geographics, the size and activity of the medical community, the growth potential of the modality being served, and other business connections are all considered. This business used the customer base established by NuTech, Inc., an independent centralized nuclear pharmacy founded by Danny Allen. With two pharmacies in operation in Tyler and College Station and a customer base of 47 hospitals and clinics the existing delivery system and pharmacist staff is used for the cyclotron facility. We then added cyclotron products to contracts with these customers to guarantee a supply. We partnered with a company in the process of developing PET imaging centers. We then built an independent imaging center attached to the cyclotron facility to allow for the use of short-lived isotopes

A Methodology for Base Camp Site Selection and Facility Layout

National Research Council Canada - National Science Library

Snyder, Frank

2002-01-01

..., and disaster relief missions throughout the world. To maintain a deployed force conducting such potentially lengthy operations, semi-permanent basecamps are required to provide the needed unit and soldier support facilities...

WEAVE: the next generation wide-field spectroscopy facility for the William Herschel Telescope : The next generation wide-field spectroscopy facility for the William Herschel Telescope

NARCIS (Netherlands)

Dalton, Gavin; Trager, Scott C.; Abrams, Don Carlos; Carter, David; Bonifacio, Piercarlo; Aguerri, J. Alfonso L.; MacIntosh, Mike; Evans, Chris; Lewis, Ian; Navarro, Ramon; Agocs, Tibor; Dee, Kevin; Rousset, Sophie; Tosh, Ian; Middleton, Kevin; Pragt, Johannes; Terrett, David; Brock, Matthew; Benn, Chris; Verheijen, Marc; Cano Infantes, Diego; Bevil, Craige; Steele, Iain; Mottram, Chris; Bates, Stuart; Gribbin, Francis J.; Rey, Jürg; Rodriguez, Luis Fernando; Delgado, Jose Miguel; Guinouard, Isabelle; Walton, Nic; Irwin, Michael J.; Jagourel, Pascal; Stuik, Remko; Gerlofsma, Gerrit; Roelfsma, Ronald; Skillen, Ian; Ridings, Andy; Balcells, Marc; Daban, Jean-Baptiste; Gouvret, Carole; Venema, Lars; Girard, Paul

We present the preliminary design of the WEAVE next generation spectroscopy facility for the William Herschel Telescope (WHT), principally targeting optical ground-based follow up of upcoming ground-based (LOFAR) and spacebased (Gaia) surveys. WEAVE is a multi-object and multi-IFU facility utilizing

Management of Decommissioning on a Multi-Facility Site

International Nuclear Information System (INIS)

Laraia, Michele; McIntyre, Peter; Visagie, Abrie

2008-01-01

The management of the decommissioning of multi-facility sites may be inadequate or inappropriate if based on approaches and strategies developed for sites consisting of only a single facility. The varied nature of activities undertaken, their interfaces and their interdependencies are likely to complicate the management of decommissioning. These issues can be exacerbated where some facilities are entering the decommissioning phase while others are still operational or even new facilities are being built. Multi-facility sites are not uncommon worldwide but perhaps insufficient attention has been paid to optimizing the overall site decommissioning in the context of the entire life cycle of facilities. Decommissioning management arrangements need to be established taking a view across the whole site. A site-wide decommissioning management system is required. This should include a project evaluation and approval process and specific arrangements to manage identified interfaces and interdependencies. A group should be created to manage decommissioning across the site, ensuring adequate and consistent practices in accordance with the management system. Decommissioning management should be aimed at the entire life cycle of facilities. In the case of multi facility sites, the process becomes more complex and decommissioning management arrangements need to be established with a view to the whole site. A site decommissioning management system, a group that is responsible for decommissioning on site, a site project evaluation and approval process and specific arrangements to manage the identified interfaces are key areas of a site decommissioning management structure that need to be addressed to ensure adequate and consistent decommissioning practices. A decommissioning strategy based on single facilities in a sequential manner is deemed inadequate

Sampling based uncertainty analysis of 10% hot leg break LOCA in large scale test facility

International Nuclear Information System (INIS)

Sengupta, Samiran; Kraina, V.; Dubey, S. K.; Rao, R. S.; Gupta, S. K.

2010-01-01

Sampling based uncertainty analysis was carried out to quantify uncertainty in predictions of best estimate code RELAP5/MOD3.2 for a thermal hydraulic test (10% hot leg break LOCA) performed in the Large Scale Test Facility (LSTF) as a part of an IAEA coordinated research project. The nodalisation of the test facility was qualified for both steady state and transient level by systematically applying the procedures led by uncertainty methodology based on accuracy extrapolation (UMAE); uncertainty analysis was carried out using the Latin hypercube sampling (LHS) method to evaluate uncertainty for ten input parameters. Sixteen output parameters were selected for uncertainty evaluation and uncertainty band between 5 th and 95 th percentile of the output parameters were evaluated. It was observed that the uncertainty band for the primary pressure during two phase blowdown is larger than that of the remaining period. Similarly, a larger uncertainty band is observed relating to accumulator injection flow during reflood phase. Importance analysis was also carried out and standard rank regression coefficients were computed to quantify the effect of each individual input parameter on output parameters. It was observed that the break discharge coefficient is the most important uncertain parameter relating to the prediction of all the primary side parameters and that the steam generator (SG) relief pressure setting is the most important parameter in predicting the SG secondary pressure

Ion Beam Facilities at the National Centre for Accelerator based Research using a 3 MV Pelletron Accelerator

Science.gov (United States)

Trivedi, T.; Patel, Shiv P.; Chandra, P.; Bajpai, P. K.

A 3.0 MV (Pelletron 9 SDH 4, NEC, USA) low energy ion accelerator has been recently installed as the National Centre for Accelerator based Research (NCAR) at the Department of Pure & Applied Physics, Guru Ghasidas Vishwavidyalaya, Bilaspur, India. The facility is aimed to carried out interdisciplinary researches using ion beams with high current TORVIS (for H, He ions) and SNICS (for heavy ions) ion sources. The facility includes two dedicated beam lines, one for ion beam analysis (IBA) and other for ion implantation/ irradiation corresponding to switching magnet at +20 and -10 degree, respectively. Ions with 60 kV energy are injected into the accelerator tank where after stripping positively charged ions are accelerated up to 29 MeV for Au. The installed ion beam analysis techniques include RBS, PIXE, ERDA and channelling.

Burden of laboratory-confirmed Campylobacter infections in Guatemala 2008-2012: results from a facility-based surveillance system.

Science.gov (United States)

Benoit, Stephen R; Lopez, Beatriz; Arvelo, Wences; Henao, Olga; Parsons, Michele B; Reyes, Lissette; Moir, Juan Carlos; Lindblade, Kim

2014-03-01

Campylobacteriosis is one of the leading causes of gastroenteritis worldwide. This study describes the epidemiology of laboratory-confirmed Campylobacter diarrheal infections in two facility-based surveillance sites in Guatemala. Clinical, epidemiologic, and laboratory data were collected on patients presenting with acute diarrhea from select healthcare facilities in the departments of Santa Rosa and Quetzaltenango, Guatemala, from January 2008 through August 2012. Stool specimens were cultured for Campylobacter and antimicrobial susceptibility testing was performed on a subset of isolates. Multidrug resistance (MDR) was defined as resistance to ≥3 antimicrobial classes. Campylobacter was isolated from 306 (6.0%) of 5137 stool specimens collected. For children Guatemala; antimicrobial resistance was high, and treatment regimens in the ambulatory setting which included metronidazole and trimethoprim-sulfamethoxazole and lacked oral rehydration were sub-optimal. Published by Elsevier Ltd.

CT hepatic perfusion measurement: Comparison of three analytic methods

International Nuclear Information System (INIS)

Kanda, Tomonori; Yoshikawa, Takeshi; Ohno, Yoshiharu; Kanata, Naoki; Koyama, Hisanobu; Takenaka, Daisuke; Sugimura, Kazuro

2012-01-01

Objectives: To compare the efficacy of three analytic methods, maximum slope (MS), dual-input single-compartment model (CM) and deconvolution (DC), for CT measurements of hepatic perfusion and assess the effects of extra-hepatic systemic factors. Materials and methods: Eighty-eight patients who were suspected of having metastatic liver tumors underwent hepatic CT perfusion. The scans were performed at the hepatic hilum 7–77 s after administration of contrast material. Hepatic arterial and portal perfusions (HAP and HPP, ml/min/100 ml) and arterial perfusion fraction (APF, %) were calculated with the three methods, followed by correlation assessment. Partial correlation analysis was used to assess the effects on hepatic perfusion values by various factors such as age, sex, risk of cardiovascular diseases, arrival time of contrast material at abdominal aorta, transit time from abdominal aorta to hepatic parenchyma, and liver dysfunction. Results: Mean HAP of MS was significantly higher than DC. HPP of CM was significantly higher than MS and CM, and HPP of MS was significantly higher than DC. There was no significant difference in APF. HAP and APF showed significant and moderate correlations among the methods. HPP showed significant and moderate correlations between CM and DC, and poor correlation between MS and CM or DC. All methods showed weak correlations between HAP or APF and age or sex. Finally, MS showed weak correlations between HAP or HPP and arrival time or cardiovascular risks. Conclusions: Hepatic perfusion values arrived at with the three methods are not interchangeable. CM and DC are less susceptible to extra-hepatic systemic factors

FT-Raman spectroscopic analysis of Nd:YAG and Er,Cr:YSGG laser irradiated enamel for preventive purposes

International Nuclear Information System (INIS)

Ana, P A; Kauffmann, C M F; Gomes, A S L; Bachmann, L; Soares, L E S; Martin, A A; Zezell, D M

2014-01-01

This study evaluated the effect of combining laser irradiation with fluoride on an enamel microstructure and demineralization by FT-Raman spectroscopy (FTRS). Eighty human enamel slabs were divided into eight groups: (G1) untreated; (G2) acidulated phosphate fluoride application (APF—1.23% F − for 4 min); (G3) Nd:YAG irradiation (84.9 J cm −2 , 60 mJ/pulse); (G4) Nd:YAG + APF; (G5) APF + Nd:YAG; (G6) Er,Cr:YSGG irradiation (2.8 J cm −2 , 12.5 mJ/pulse); (G7) Er,Cr:YSGG + APF; and (G8) APF + Er,Cr:YSGG. After treatment, the samples were submitted to a ten-day pH-cycling model. Chemical changes were determined on the slabs before and after treatment, and also after pH-cycling, by FTRS in the range 400−4000 cm −1 . The inorganic bands at 440, 590, 870, 960, 1100 cm −1 , and the organic bands at 1270, 1450, 1670, 2945 cm −1 were considered. Demineralization promoted reduction in organic contents; Nd:YAG laser irradiation promoted loss of carbonate and organic content, while Er,Cr:YSGG did not produce significant changes in the relative band intensities of organic and inorganic contents of the enamel. In lased samples, no effects caused by pH-cycling on enamel were observed. In conclusion, laser treatment and its association with fluoride can somehow interfere with the demineralization dynamics, reducing its effects over the enamel. (paper)

A cask maintenance facility feasibility study

International Nuclear Information System (INIS)

Rennich, M.J.; Medley, L.G.; Attaway, C.R.

1989-01-01

The Oak Ridge National Laboratory (ORNL) is supporting the USDOE Office of Civilian Radioactive Waste Management (OCRWM) in developing a transportation system for spent nuclear fuel (SNF) and defense high level waste (HLW) as a part of the Federal Waste Management System (FWMS). In early 1988, a feasibility study was undertaken to design a stand-alone, green field facility for maintaining the FWMS casks. The feasibility study provided an initial layout facility design, an estimate of the construction cost, and an acquisition schedule for a Cask Maintenance Facility (CMF). The study also helped to define the interfaces between the transportation system and the waste generators, the repository, and a Monitored Retrieveable Storage (MRS) facility. The data, design, and estimated cost resulting from the study have been organized for use in the total transportation system decision-making process. Most importantly, the feasibility study also provides a foundation for continuing design and planning efforts. The feasibility study was based on an assumed stand-alone green field configuration because of the flexibility this design approach provides. A stand-alone facility requires the inclusion with support functions as well as the primary process facilities thus yielding a comprehensive design evaluation and cost estimate. For example, items such as roads, security and waste processing which might be shared with an integrated or collocated facility have been fully costed in the feasibility study. Thus, while the details of the facility design might change, the overall concept used in the study can be applied to other facility configurations as planning for the total FWMS develops

Analysis of Student Satisfaction Toward Quality of Service Facility

Science.gov (United States)

Napitupulu, D.; Rahim, R.; Abdullah, D.; Setiawan, MI; Abdillah, LA; Ahmar, AS; Simarmata, J.; Hidayat, R.; Nurdiyanto, H.; Pranolo, A.

2018-01-01

The development of higher education is very rapid rise to the tight competition both public universities and private colleges. XYZ University realized to win the competition, required continuous quality improvement, including the quality of existing service facilities. Amenities quality services is believed to support the success of the learning activities and improve user satisfaction. This study aims to determine the extent to which the quality of the services effect on user satisfaction. The research method used is survey-based questionnaire that measure perception and expectation. The results showed a gap between perception and expectations of the respondents have a negative value for each item. This means XYZ service facility at the university is not currently meet the expectations of society members. Three service facility that has the lowest index is based on the perception of respondents is a laboratory (2.56), computer and multimedia (2.63) as well as wifi network (2.99). The magnitude of the correlation between satisfaction with the quality of service facilities is 0.725 which means a strong and positive relationship. The influence of the quality of service facilities to the satisfaction of the students is 0.525 meaning that the variable quality of the services facility can explain 52.5% of the variable satisfaction. The study provided recommendations for improvements to enhance the quality of services facility at the XYZ university facilities.

An Evaluation of Facility Maintenance and Repair Strategies of Select Companies

National Research Council Canada - National Science Library

Sharp, Christopher

2002-01-01

...) with the benefits derived from those facilities. This thesis documents how a selection of companies implemented that balance by determining their facilities requirements based on their chosen facility condition level and how they then allocated funds...

First operations of the LNS heavy ions facility

International Nuclear Information System (INIS)

Calabretta, L.; Ciavola, G.; Cuttone, G.; Gammino, S.; Gmaj, P.; Migneco, E.; Raia, G.; Rifuggiato, D.; Rovelli, A.; Sura, J.; Scuderi, V.; Acerbi, E.; Alessandria, F.; Bellomo, G.; Bosotti, A.; Martinis, C. de; Giove, D.; Michelato, P.; Pagani, C.; Rossi, L.

1996-01-01

A heavy ion facility is now available at laboratorio nazionale del Sud (LNS) of Catania. It can deliver beams with an energy up to 100 MeV/amu. The facility is based on a 15 MV HVEC tandem and a K=800 superconducting cyclotron as booster. During the last year, the facility came into operation. A 58 Ni beam delivered by the tandem has been radially injected in the SC and then has been accelerated and extracted at 30 MeV/amu. In this paper the status of the facility together with the experience gained during the commissioning will be extensively reported. (orig.)

Remote handling technology for nuclear fuel cycle facilities

International Nuclear Information System (INIS)

Sakai, Akira; Maekawa, Hiromichi; Ohmura, Yutaka

1997-01-01

Design and R and D on nuclear fuel cycle facilities has intended development of remote handling and maintenance technology since 1977. IHI has completed the design and construction of several facilities with remote handling systems for Power Reactor and Nuclear Fuel Development Corporation (PNC), Japan Atomic Energy Research Institute (JAERI), and Japan Nuclear Fuel Ltd. (JNFL). Based on the above experiences, IHI is now undertaking integration of specific technology and remote handling technology for application to new fields such as fusion reactor facilities, decommissioning of nuclear reactors, accelerator testing facilities, and robot simulator-aided remote operation systems in the future. (author)

Accelerator-based research facility of UGC as an inter-university centre

International Nuclear Information System (INIS)

Mehta, G.K.

1994-01-01

A 15-UD Pelletron has been operating as a users facility from July 1991. It is being utilised by a large number of universities and other institutions for research in basic nuclear physics, materials science, atomic physics, radiobiology and radiation chemistry. There is an on-going programme for augmenting the accelerator facilities by injecting Pelletron beams into superconducting linear accelerator modules. Superconducting niobium resonators are being developed at Argonne National Laboratory as a joint collaborative effort. All other things such as cryostat, rf-instrumentation, cryogene distribution system, computer control etc. are being done indigenously. Research possibilities are described. (author). 6 refs., 4 figs

University multi-user facility survey-2010.

Science.gov (United States)

Riley, Melissa B

2011-12-01

Multi-user facilities serve as a resource for many universities. In 2010, a survey was conducted investigating possible changes and successful characteristics of multi-user facilities, as well as identifying problems in facilities. Over 300 surveys were e-mailed to persons identified from university websites as being involved with multi-user facilities. Complete responses were received from 36 facilities with an average of 20 years of operation. Facilities were associated with specific departments (22%), colleges (22%), and university research centers (8.3%) or were not affiliated with any department or college within the university (47%). The five most important factors to succeed as a multi-user facility were: 1) maintaining an experienced, professional staff in an open atmosphere; 2) university-level support providing partial funding; 3) broad client base; 4) instrument training programs; and 5) an effective leader and engaged strategic advisory group. The most significant problems were: 1) inadequate university financial support and commitment; 2) problems recovering full service costs from university subsidies and user fees; 3) availability of funds to repair and upgrade equipment; 4) inability to retain highly qualified staff; and 5) unqualified users dirtying/damaging equipment. Further information related to these issues and to fee structure was solicited. Overall, there appeared to be a decline in university support for facilities and more emphasis on securing income by serving clients outside of the institution and by obtaining grants from entities outside of the university.

THE PRIMARY TARGET FACILITY FOR A NEUTRINO FACTORY BASED ON MUON BEAMS

International Nuclear Information System (INIS)

HASSENEIN, A.; KAHN, S.A.; KING, B.J.; KIRK, H.G.; LUDEWIG, H.; PALMER, R.B.; PEARSON, C.E.; SAMULYAK, R.; SIMOS, N.; STUMER, I.; THIEBERGER, P.; WEGGEL, R.J.

2001-01-01

Neutrino beams from the decay of muons in a storage ring offer the prospect of very high flux, well-understood spectra, and equal numbers of electron and muon neutrinos, as desirable for detailed exploration of neutrino oscillations via long baseline detectors [1]. Such beams require. large numbers of muons, and hence a high performance target station at which a 1-4 MW proton beam of 16-24 GeV impinges on a compact target, all inside a high field solenoid channel to capture as much of the phase volume of soft pions as possible. A first concept was based on a carbon target, as reported in 2000 the Neutrino Factory Study-I [2]. A higher performance option based on a free mercury jet has been studied in 2001 as part of the Neutrino Factory Feasibility Study-II [3,4]. An overview of a mercury jet target facility is presented here, including requirements, design concept and summaries of simulated performance. Further details are presented in related papers at this conference

User's guide for the KBERT 1.0 code: For the knowledge-based estimation of hazards of radioactive material releases from DOE nuclear facilities

International Nuclear Information System (INIS)

Browitt, D.S.; Washington, K.E.; Powers, D.A.

1995-07-01

The possibility of worker exposure to radioactive materials during accidents at nuclear facilities is a principal concern of the DOE. The KBERT software has been developed at Sandia National Laboratories under DOE support to address this issue by assisting in the estimation of risks posed by accidents at chemical and nuclear facilities. KBERT is an acronym for Knowledge-Based system for Estimating hazards of Radioactive material release Transients. The current prototype version of KBERT focuses on calculation of doses and consequences to in-facility workers due to accidental releases of radioactivity. This report gives detailed instructions on how a user who is familiar with the design, layout and potential hazards of a facility can use KBERT to assess the risks to workers in that facility. KBERT is a tool that allows a user to simulate possible accidents and observe the predicted consequences. Potential applications of KBERT include the evaluation of the efficacy of evacuation practices, worker shielding, personal protection equipment and the containment of hazardous materials

Future directions of accelerator-based NP and HEP facilities

Energy Technology Data Exchange (ETDEWEB)

Roser, T.

2011-07-24

Progress in particle and nuclear physics has been closely connected to the progress in accelerator technologies - a connection that is highly beneficial to both fields. This paper presents a review of the present and future facilities and accelerator technologies that will push the frontiers of high-energy particle interactions and high intensity secondary particle beams.

Facility and market factors affecting transitions from nursing home to community.

Science.gov (United States)

Arling, Greg; Abrahamson, Kathleen A; Cooke, Valerie; Kane, Robert L; Lewis, Teresa

2011-09-01

Research into nursing home transitions has given limited attention to the facility or community contexts. To identify facility and market factors affecting transitions of nursing home residents back to the community. Multilevel models were used to estimate effects of facility and market factors on facility-level community discharge rates after controlling for resident demographic, health, and functional conditions. Facility discharge rates were adjusted using Empirical Bayes estimation. Annual cohort of first-time admissions (N=24,648) to 378 Minnesota nursing facilities in 75 nursing home markets from July 2005 to June 2006. Community discharge within 90 days of admission; facility occupancy, payer mix, ownership, case-mix acuity, size, admissions from hospitals, nurse staffing level, and proportion of admissions preferring or having support to return to the community; and nursing market population size, average occupancy, market concentration, and availability of home and community-based services. Rates of community discharge (Empirical Bayes residual) were highest in facilities with more residents preferring community discharge, more Medicare days, higher nurse staffing levels, and higher occupancy. In addition, facilities had higher community discharge rates if they were located in markets with a greater ratio of home and community-based services recipients to nursing home residents and with larger populations. State Medicaid programs should undertake system-level interventions that encourage nursing facilities to reduce unused bed capacity, balance the mix of payers, invest in nurse staffing, and take other steps to promote community discharges. In addition, states should increase home and community-based services, particularly in markets with low community discharge rates.

Facility effluent monitoring plan determinations for the 200 Area facilities

International Nuclear Information System (INIS)

Nickels, J.M.

1991-11-01

The following facility effluent monitoring plan determinations document the evaluations conducted for the Westinghouse Hanford Company 200 Area facilities (chemical processing, waste management, 222-S Laboratory, and laundry) on the Hanford Site in south central Washington State. These evaluations determined the need for facility effluent monitoring plans for the 200 Area facilities. The facility effluent monitoring plan determinations have been prepared in accordance with A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438 (WHC 1991). The Plutonium/Uranium Extraction Plant and UO 3 facility effluent monitoring plan determinations were prepared by Los Alamos Technical Associates, Richland, Washington. The Plutonium Finishing Plant, Transuranic Waste Storage and Assay Facility, T Plant, Tank Farms, Low Level Burial Grounds, and 222-S Laboratory determinations were prepared by Science Applications International Corporation of Richland, Washington. The B Plant Facility Effluent Monitoring Plan Determination was prepared by ERCE Environmental Services of Richland, Washington

Women's preferences for obstetric care in rural Ethiopia: a population-based discrete choice experiment in a region with low rates of facility delivery.

Science.gov (United States)

Kruk, M E; Paczkowski, M M; Tegegn, A; Tessema, F; Hadley, C; Asefa, M; Galea, S

2010-11-01

Delivery attended by skilled professionals is essential to reducing maternal mortality. Although the facility delivery rate in Ethiopia's rural areas is extremely low, little is known about which health system characteristics most influence women's preferences for delivery services. In this study, women's preferences for attributes of health facilities for delivery in rural Ethiopia were investigated. A population-based discrete choice experiment (DCE) was fielded in Gilgel Gibe, in southwest Ethiopia, among women with a delivery in the past 5 years. Women were asked to select a hypothetical health facility for future delivery from two facilities on a picture card. A hierarchical Bayesian procedure was used to estimate utilities associated with facility attributes: distance, type of provider, provider attitude, drugs and medical equipment, transport and cost. 1006 women completed 8045 DCE choice tasks. Among them, 93.8% had delivered their last child at home. The attributes with the greatest influence on the overall utility of a health facility for delivery were availability of drugs and equipment (mean β=3.9, pdelivery nonetheless value health facility attributes that indicate high technical quality: availability of drugs and equipment and physician providers. Well-designed policy experiments that measure the contribution of quality improvements to facility delivery rates in Ethiopia and other countries with low health service utilisation and high maternal mortality may inform national efforts to reduce maternal mortality.

The added value of Facility management in the educational environment

NARCIS (Netherlands)

Kok, H.B.; Mobach, M.; Omta, S.W.F.

2011-01-01

Purpose – The purpose of this paper is to define the added value of facility management (FM) in general and to develop a typology of facility services based on their added value in the educational environment. Design/methodology/approach – This paper is based on a literature review and first

Ice condenser testing facility and plans

International Nuclear Information System (INIS)

Kannberg, L.D.; Ross, B.A.; Eschbach, E.J.; Ligotke, M.W.

1987-01-01

A facility is being constructed to experimentally validate the ICEDF computer code. The code was developed to estimate the extent of fission product retention in the ice compartments of pressurized water reactor ice condenser containment systems during severe accidents. The design and construction of the facility is based on a test design that addresses the validation needs of the code for conditions typical of those expected to occur during severe pressurized water reactor accidents. Detailed facility design has followed completion of a test design (i.e., assembled test cases each involving a different set of aerosol and thermohydraulic flow conditions). The test design was developed with the aid of statistical test design software and was scrutinized for applicability with the aid of ICEDF simulations. The test facility will incorporate a small section of a prototypic ice condenser (e.g., a cross section comprising the equivalent of four 1-ft-diameter ice baskets to their full prototypic height of 48 ft). The development of the test design, the detailed facility design, and the construction progress are described in this paper

Facilities & Leadership

Data.gov (United States)

Department of Veterans Affairs — The facilities web service provides VA facility information. The VA facilities locator is a feature that is available across the enterprise, on any webpage, for the...

Utility of Risk Models in Decision Making After Radical Prostatectomy: Lessons from a Natural History Cohort of Intermediate- and High-Risk Men.

Science.gov (United States)

Ross, Ashley E; Yousefi, Kasra; Davicioni, Elai; Ghadessi, Mercedeh; Johnson, Michael H; Sundi, Debasish; Tosoian, Jeffery J; Han, Misop; Humphreys, Elizabeth B; Partin, Alan W; Walsh, Patrick C; Trock, Bruce J; Schaeffer, Edward M

2016-03-01

Current guidelines suggest adjuvant radiation therapy for men with adverse pathologic features (APFs) at radical prostatectomy (RP). We examine at-risk men treated only with RP until the time of metastasis. To evaluate whether clinicopathologic risk models can help guide postoperative therapeutic decision making. Men with National Comprehensive Cancer Network intermediate- or high-risk localized prostate cancer undergoing RP in the prostate-specific antigen (PSA) era were identified (n=3089). Only men with initial undetectable PSA after surgery and who received no therapy prior to metastasis were included. APFs were defined as pT3 disease or positive surgical margins. Area under the receiver operating characteristic curve (AUC) for time to event data was used to measure the discrimination performance of the risk factors. Cumulative incidence curves were constructed using Fine and Gray competing risks analysis to estimate the risk of biochemical recurrence (BCR) or metastasis, taking censoring and death due to other causes into consideration. Overall, 43% of the cohort (n=1327) had APFs at RP. Median follow-up for censored patients was 5 yr. Cumulative incidence of metastasis was 6% at 10 yr after RP for all patients. Cumulative incidence of metastasis among men with APFs was 7.5% at 10 yr after RP. Among men with BCR, the incidence of metastasis was 38% 5 yr after BCR. At 10 yr after RP, time-dependent AUC for predicting metastasis by Cancer of the Prostate Risk Assessment Postsurgical or Eggener risk models was 0.81 (95% confidence interval [CI], 0.72-0.97) and 0.78 (95% CI, 0.67-0.97) in the APF population, respectively. At 5 yr after BCR, these values were lower (0.58 [95% CI, 0.50-0.66] and 0.70 [95% CI, 0.63-0.76]) among those who developed BCR. Use of risk model cut points could substantially reduce overtreatment while minimally increasing undertreatment (ie, use of an Eggener cut point of 2.5% for treatment of men with APFs would spare 46% from treatment

Facility model for the Los Alamos Plutonium Facility

International Nuclear Information System (INIS)

Coulter, C.A.; Thomas, K.E.; Sohn, C.L.; Yarbro, T.F.; Hench, K.W.

1986-01-01

The Los Alamos Plutonium Facility contains more than sixty unit processes and handles a large variety of nuclear materials, including many forms of plutonium-bearing scrap. The management of the Plutonium Facility is supporting the development of a computer model of the facility as a means of effectively integrating the large amount of information required for material control, process planning, and facility development. The model is designed to provide a flexible, easily maintainable facility description that allows the faciltiy to be represented at any desired level of detail within a single modeling framework, and to do this using a model program and data files that can be read and understood by a technically qualified person without modeling experience. These characteristics were achieved by structuring the model so that all facility data is contained in data files, formulating the model in a simulation language that provides a flexible set of data structures and permits a near-English-language syntax, and using a description for unit processes that can represent either a true unit process or a major subsection of the facility. Use of the model is illustrated by applying it to two configurations of a fictitious nuclear material processing line

Integral Monitored Retrievable Storage (MRS) Facility conceptual design report

International Nuclear Information System (INIS)

1985-09-01

This document, Volume 5 Book 1, contains cost estimate summaries for a monitored retrievable storage (MRS) facility. The cost estimate is based on the engineering performed during the conceptual design phase of the MRS Facility project

Tandem mirror technology demonstration facility

Energy Technology Data Exchange (ETDEWEB)

1983-10-01

This report describes a facility for generating engineering data on the nuclear technologies needed to build an engineering test reactor (ETR). The facility, based on a tandem mirror operating in the Kelley mode, could be used to produce a high neutron flux (1.4 MW/M/sup 2/) on an 8-m/sup 2/ test area for testing fusion blankets. Runs of more than 100 h, with an average availability of 30%, would produce a fluence of 5 mW/yr/m/sup 2/ and give the necessary experience for successful operation of an ETR.

Tandem mirror technology demonstration facility

International Nuclear Information System (INIS)

1983-10-01

This report describes a facility for generating engineering data on the nuclear technologies needed to build an engineering test reactor (ETR). The facility, based on a tandem mirror operating in the Kelley mode, could be used to produce a high neutron flux (1.4 MW/M 2 ) on an 8-m 2 test area for testing fusion blankets. Runs of more than 100 h, with an average availability of 30%, would produce a fluence of 5 mW/yr/m 2 and give the necessary experience for successful operation of an ETR

The Medical Cyclotron Facility in RMC, Parel, BARC

International Nuclear Information System (INIS)

Gopalakrishna, Arjun; Banerjee, Sharmila

2017-01-01

The Medical Cyclotron Facility in Radiation Medicine Centre (RMC) is the first one of its kind, installed in 2002. "1"8F based radiotracers are produced in this facility on a routine basis for Positron Emission Tomography (PET), of in-house patients, as well as for supply to other nuclear medicine centers in Mumbai as well as Pune. The facility consists of the following sub parts - Cyclotron and support equipment; Radiochemistry synthesis laboratory; Quality control (QC) laboratory

Annual report to the Laser Facility Committee, 1982

International Nuclear Information System (INIS)

1982-03-01

The report covers the work done at, or in association with, the Central Laser Facility during the year April 1981 to March 1982 under the headings; glass laser facility development, gas laser development, laser plasma interactions, transport and particle emission studies, ablative acceleration and compression studies, spectroscopy and XUV lasers, and, theory and computation. Publications based on the work of the facility which have either appeared or been accepted for publication during the year are listed. (U.K.)

ECR ion source based low energy ion beam facility