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Sample records for facility agreement ffa

  1. Oak Ridge Reservation Federal Facility Agreement: Quarterly report for the Environmental Restoration Program. Volume 2, January--March 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This report provides information about ER Program activities conducted on the Oak Ridge Reservation under the Federal Facility Agreement (FFA). Specifically, it includes information on milestones scheduled for completion during the reporting period as well as scheduled for completion during the next reporting period (quarter), accomplishments of the ER Program, concerns related to program work, and scheduled activities for the next quarter. It also provides a listing of the identity and assigned tasks of contractors performing ER Program work under the FFA.

  2. Oak Ridge Reservation Federal Facility Agreement for the Environmental Restoration Program. Volume 1, Quarterly report, October--December 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This Oak Ridge Reservation Federal Facility Agreement Quarterly Report for the Environmental Restoration Program was prepared to satisfy requirements for progress reporting on Environmental Restoration Program (ER) activities as specified in the Oak Ridge Reservation Federal Facility Agreement (FFA) established between the US Department of Energy (DOE), the US Environmental Protection Agency, and the Tennessee Department of Environment and Conservation. The reporting period covered in this document is October through December 1995. This work was performed under Work Breakdown Structure 1.4.12.2.3.04 (Activity Data Sheet 8304). Publication of this document meets two FFA milestones. The FFA Quarterly Report meets an FFA milestone defined as 30 days following the end of the applicable reporting period. Appendix A of this report meets the FFA milestone for the Annual Removal Action Report for the period FYs 1991--95. This document provides information about ER Program activities conducted on the Oak Ridge Reservation under the FFA. Specifically, it includes information on milestones scheduled for completion during the reporting period, as well as scheduled for completion during the next reporting period (quarter); accomplishments of the ER Program; concerns related to program work; and scheduled activities for the next quarter. It also provides a listing of the identity and assigned tasks of contractors performing ER Program work under the FFA.

  3. Federal Facility Agreement Annual Progress Report for FY 1998

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, E.

    1999-08-04

    This FFA Annual Progress Report has been developed to summarize the information for activities performed during the Fiscal Year 1998 (October 1, 1997, to September 30, 1998) and activities planned for Fiscal Year 1999 by U.S. EPA, SCDHEC, and SRS at those units and areas identified for remediation in the Agreement.

  4. Oak Ridge Reservation Federal Facility Agreement. Quarterly report for the Environmental Restoration Program. Volume 4, July 1995--September 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    This quarterly progress report satisfies requirements for the Environmental Restoration (ER) Program that are specified in the Oak Ridge Reservation Federal Facility Agreement (FFA) established between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC). The reporting period covered herein is July through September 1995 (fourth quarter of FY 1995). Sections 1.1 and 1.2 provide respectively the milestones scheduled for completion during the reporting period and a list of documents that have been proposed for transmittal during the following quarter but have not been approved as FY 1995 commitments.

  5. Oak Ridge reservation federal facility agreement for the Environmental Restoration Program. Volume 1. Quarterly report, October--December 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    This quarterly progress report satisfies requirements for the Environmental Restoration (ER) Program that are specified in the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC). The reporting period covered is October through December 1993 (first quarter of FY 1994). Sections 1.1 and 1.2 provide respectively the milestones scheduled for completion during the reporting period and a list of documents that have been proposed for transmittal during the following quarter but have not been approved as FY 1994 commitments.

  6. Horticulture and the FFA

    Science.gov (United States)

    Nelson, Clifford L.

    1975-01-01

    The article offers teachers of vocational horticulture a number of specific suggestions for organizing FFA horticulture chapters that will appeal to urban and suburban students and that will improve the quality of their learning. (AJ)

  7. Oak Ridge Reservation Federal Facility Agreement quarterly report for the environmental restoration program. Volume 2: January--March 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    This quarterly progress report satisfies requirements for the Environmental Restoration (ER) Program that are specified in the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the US Department of Energy (DOE), the US Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC). Sections 1.1 and 1.2 provide respectively the milestones scheduled for completion during the reporting period and a list of documents that have been proposed for transmittal during the following quarter but have not been approved as FY 1995 commitments. The report describes the technical status of the following: Y-12 Plant; Oak Ridge National Lab; K-25 Plant; and Oak Ridge Reservation boundary areas. The report also describes technical programs, namely: the Oak Ridge environmental information system, remote sensing and special survey program, and the risk assessment program.

  8. Oak Ridge Reservation Federal Facility Agreement quarterly report for the environmental restoration program. Volume 3: April--June 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This quarterly progress report satisfies requirements for the Environmental Restoration (ER) Program that are specified in the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the US Department of Energy (DOE), the US Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC). Sections 1.1 and 1.2 provide respectively the milestones scheduled for completion during the reporting period and a list of documents that have been proposed for transmittal during the following quarter but have not been approved as FY 1995 commitments. The report describes the technical status of the following: Y-12 Plant; Oak Ridge National Lab; K-25 Plant; and Oak Ridge Reservation boundary areas. The report also describes technical programs, namely: the Oak Ridge environmental information system, remote sensing and special survey program, and the risk assessment program.

  9. Oak Ridge Reservation Federal Facility agreement quarterly report for the Environmental Restoration Program, January--March 1994. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    This quarterly progress report satisfies requirements for the Environmental Restoration (ER) Program that are specified in the Oak Ridge Reservation (ORR) Federal Facility Agreement (FFA) established between the US Department of Energy (DOE), the US Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC). The reporting period covered herein is January through March 1994 (second quarter of FY 1994). Sections 1.1 and 1.2 provide respectively the milestones scheduled for completion during the reporting period and a list of documents that have been proposed for transmittal during the following quarter but have not been approved as FY 1994 commitments. Section 2 covers significant accomplishments. Section 3 discusses technical status at the Oak Ridge Y-12 Plant, Oak Ridge National Laboratory, Oak Ridge K-25 Site, and Clinch River. Technical oversight and technical programs are also covered. Section 4 covers responds action contractor assignments.

  10. Implementation plan for liquid low-level radioactive waste systems under the FFA for Fiscal years 1996 and 1997 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) requires a Federal Facility Agreement (FFA) for federal facilities placed on the National Priorities List. The Oak Ridge Reservation was placed on that list on December 21, 1989, and the agreement was signed in November 1991 by the Department of Energy Oak Ridge Operations Office (DOE-ORO), the U.S. Environmental Protection Agency (EPA)-Region IV, and the Tennessee Department of Environment and Conservation (TDEC). The effective date of the FFA was January 1, 1992. Section IX and Appendix F of the agreement impose design and operating requirements on the Oak Ridge National Laboratory (ORNL) liquid low-level radioactive waste (LLLW) tank systems and identify several plans, schedules, and assessments that must be submitted to EPA/TDEC for review of approval. The issue of ES/ER-17&D1 Federal Facility Agreement Plans and Schedules for Liquid Low-Level Radioactive Waste Tank Systems at Oak Ridge National Laboratory, Oak Ridge, Tennessee in March 1992 transmitted to EPA/TDEC those plans and schedules that were required within 60 to 90 days of the FFA effective date. This document updates the plans, schedules, and strategy for achieving compliance with the FFA as presented in ES/ER-17&D I and summarizes the progress that has been made to date. This document supersedes all updates of ES/ER- 17&D 1. Chapter 1 describes the history and operation of the ORNL LLLW System and the objectives of the FFA. Chapters 2 through 5 contain the updated plans and schedules for meeting FFA requirements. This document will continue to be periodically reassessed and refined to reflect newly developed information and progress.

  11. Prevocational Agribusiness and the FFA

    Science.gov (United States)

    James, Kenneth A.

    1975-01-01

    The author discusses the development of the career education concept relating to agribusiness at the junior high and middle school level. In the prevocational agribusiness program, it is also effective to supplement the program with an FFA chapter. (JB)

  12. 76 FR 4369 - Interim Deputation Agreements; Interim BIA Adult Detention Facility Guidelines

    Science.gov (United States)

    2011-01-25

    ... Bureau of Indian Affairs Interim Deputation Agreements; Interim BIA Adult Detention Facility Guidelines... publication of the Interim BIA Adult Detention Facility Guidelines and the Interim Model Deputation Agreements... of 2010. Three Interim Model Deputation Agreements will be used: one agreement for tribes in...

  13. How harmless is FFA enhancement?

    Science.gov (United States)

    Tesserommatis, C; Tsopanakis, C; Symeonoglou, G; Loukissa, M; Kouvarou, E; Varonos, D D

    1996-01-01

    Standard heparin as well as low molecular weight heparin (LMWH) increase lipid levels in serum. It has been reported that a diet rich in long chain saturated fatty acids can enhance the susceptibility to experimental thrombosis. The mechanism by which serum fatty acids may provoke thrombosis is not clear. It is possible that the fatty acids change the properties of the cell membrane and thereby modify the response of platelets to aggregating agents. Heparin and its LMW fractions, by mobilising lipoprotein lipase that hydrolyses serum triglycerides (TG), cause the serum TG to increase, a well known "clearing effect' of heparin in turbid lipemic plasma. This effect may have no significance when it lasts for a short time; however, a long-lasting heparin effect on TG serum levels may have important consequences. The purpose of this study was to examine the time span of the action of heparin and its fractions and to investigate variations in the concentration of digoxin, which is a compound with narrow therapeutic width. The investigated substances after 2 days administration, provoked serum concentration increases of free fatty acids (FFA), TG and HDL-C. Seven days after stopping drug administration, FFA and HDL-C levels remained high, while triglycerides declined. Serum total cholesterol remained unchanged throughout. Digoxin levels increased non-significantly after heparin administration and during swimming stress, while a lipid diet caused a serum digoxin concentration increase.

  14. Occupational radiation Exposure at Agreement State-Licensed Materials Facilities, 1997-2010

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Nuclear Regulatory Commission, Office of Nuclear Regulatory Research

    2012-07-07

    The purpose of this report is to examine occupational radiation exposures received under Agreement State licensees. As such, this report reflects the occupational radiation exposure data contained in the Radiation Exposure Information and Reporting System (REIRS) database, for 1997 through 2010, from Agreement State-licensed materials facilities.

  15. Robust expertise effects in right FFA.

    Science.gov (United States)

    McGugin, Rankin Williams; Newton, Allen T; Gore, John C; Gauthier, Isabel

    2014-10-01

    The fusiform face area (FFA) is one of several areas in occipito-temporal cortex whose activity is correlated with perceptual expertise for objects. Here, we investigate the robustness of expertise effects in FFA and other areas to a strong task manipulation that increases both perceptual and attentional demands. With high-resolution fMRI at 7T, we measured responses to images of cars, faces and a category globally visually similar to cars (sofas) in 26 subjects who varied in expertise with cars, in (a) a low load 1-back task with a single object category and (b) a high load task in which objects from two categories were rapidly alternated and attention was required to both categories. The low load condition revealed several areas more active as a function of expertise, including both posterior and anterior portions of FFA bilaterally (FFA1/FFA2, respectively). Under high load, fewer areas were positively correlated with expertise and several areas were even negatively correlated, but the expertise effect in face-selective voxels in the anterior portion of FFA (FFA2) remained robust. Finally, we found that behavioral car expertise also predicted increased responses to sofa images but no behavioral advantages in sofa discrimination, suggesting that global shape similarity to a category of expertise is enough to elicit a response in FFA and other areas sensitive to experience, even when the category itself is not of special interest. The robustness of expertise effects in right FFA2 and the expertise effects driven by visual similarity both argue against attention being the sole determinant of expertise effects in extrastriate areas.

  16. Critical Theory View of the National FFA Convention

    Science.gov (United States)

    Martin, Michael J.; Kitchel, Tracy

    2015-01-01

    Urban FFA members face unique challenges if they want to become active members in the National FFA Organization. FFA leaders have realized that the FFA organization does not represent the evolving demographics of America and have made efforts to cater to urban and diverse high school audiences with some success. This study seeks to explore this…

  17. Urban FFA Members' Sense of the Organizational Culture of the FFA

    Science.gov (United States)

    Martin, Michael J.; Kitchel, Tracy

    2014-01-01

    Organizational culture shapes how members of a group act. The culture has the power to exclude potential new members who do not fit into the culture of the organization. Research on urban school-based agriculture programs has indicated that urban agriculture students face barriers to their participation in the National FFA Organization (FFA).…

  18. Wind tunnel test of the FFA-W3-241, FFA-W3-301 and NACA 63-430 airfoils

    Energy Technology Data Exchange (ETDEWEB)

    Fuglsang, P.; Antoniou, I.; Dahl, K.S.; Madsen, H.A.

    1998-12-01

    This report deals with 2D measurements of the FFA-W3-241, FFA-W3-301 and NACA 63-430 airfoils. The aerodynamic properties were measured at Re = 1.6x10{sup 6}. The VELUX open jet wind tunnel with a background turbulence intensity of 1% was used. The airfoil sections had a chord of 0.60 m and a span of 1.9 m and end plates were used to minimize 3D flow effects. The measurements comprised both static and dynamic inflow where dynamic inflow was obtained by pitching the airfoil in a harmonic motion. We tested the influence from vortex generators and leading edge roughness both individually and in combination. The aerodynamic characteristics were measured and the agreement between calculations and measurements was fair for FFA-W3-241 but not good for FFA-W3-301 and NACA 63-430. In general calculations overestimated maximum C{sub L} and sometimes underestimated minimum C{sub D}. Maximum C{sub L} for smooth flow was in good agreement with calculated maximum C{sub L} for leading edge transition flow and this could serve as a worst case calculation. We determined the influence from vortex generators and they should always be applied on thick airfoils to increase maximum C{sub L}. We determined the influence from leading edge roughness, which reduced maximum C{sub L} and increased minimum C{sub D}. Compared with the NACA 63-4xx airfoils, the FFA-W3 airfoils were found better suited for the inboard part of a wind turbine blade both with and without vortex generators. (au) EFP-94; EFP-95; EFP-97. 8 tabs., 195 ills., 13 refs.

  19. Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists

    Science.gov (United States)

    Schmidt, Johannes; Smith, Nicola J.; Christiansen, Elisabeth; Tikhonova, Irina G.; Grundmann, Manuel; Hudson, Brian D.; Ward, Richard J.; Drewke, Christel; Milligan, Graeme; Kostenis, Evi; Ulven, Trond

    2011-01-01

    Free fatty acid receptor 2 (FFA2; GPR43) is a G protein-coupled seven-transmembrane receptor for short-chain fatty acids (SCFAs) that is implicated in inflammatory and metabolic disorders. The SCFA propionate has close to optimal ligand efficiency for FFA2 and can hence be considered as highly potent given its size. Propionate, however, does not discriminate between FFA2 and the closely related receptor FFA3 (GPR41). To identify FFA2-selective ligands and understand the molecular basis for FFA2 selectivity, a targeted library of small carboxylic acids was examined using holistic, label-free dynamic mass redistribution technology for primary screening and the receptor-proximal G protein [35S]guanosine 5′-(3-O-thio)triphosphate activation, inositol phosphate, and cAMP accumulation assays for hit confirmation. Structure-activity relationship analysis allowed formulation of a general rule to predict selectivity for small carboxylic acids at the orthosteric binding site where ligands with substituted sp3-hybridized α-carbons preferentially activate FFA3, whereas ligands with sp2- or sp-hybridized α-carbons prefer FFA2. The orthosteric binding mode was verified by site-directed mutagenesis: replacement of orthosteric site arginine residues by alanine in FFA2 prevented ligand binding, and molecular modeling predicted the detailed mode of binding. Based on this, selective mutation of three residues to their non-conserved counterparts in FFA3 was sufficient to transfer FFA3 selectivity to FFA2. Thus, selective activation of FFA2 via the orthosteric site is achievable with rather small ligands, a finding with significant implications for the rational design of therapeutic compounds selectively targeting the SCFA receptors. PMID:21220428

  20. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

    DEFF Research Database (Denmark)

    Schmidt, Johannes; Smith, Nicola J; Christiansen, Elisabeth;

    2011-01-01

    Free fatty acid receptor 2 (FFA2, GPR43) is a G protein-coupled 7-transmembrane receptor for short chain fatty acids (SCFAs) that is implicated in inflammatory and metabolic disorders. The SCFA propionate has close to optimal ligand efficiency for FFA2, and can hence be considered as highly poten...

  1. The Benefits of FFA Membership as Part of Agricultural Education

    Science.gov (United States)

    Rose, Chelsea; Stephens, Carrie A.; Stripling, Christopher; Cross, Tim; Sanok, Danielle E.; Brawner, Shelby

    2016-01-01

    The study sought to identify the benefits of FFA membership based on the fulfillment of three basic human needs: love and belonging, self-esteem, and self-actualization. The study focused on the fulfillment of FFA members' basic human needs as defined by Abraham Maslow. The three needs on which this study focused are: love and belonging,…

  2. Agrarianism: An Ideology of the National FFA Organization

    Science.gov (United States)

    Martin, Michael J.; Kitchel, Tracy

    2013-01-01

    The traditions of the National FFA Organization (FFA) are grounded in agrarianism. This ideology focuses on the ability of farming and nature to develop citizens and integrity within people. Agrarianism has been an important thread of American rhetoric since the founding of country. The ideology has morphed over the last two centuries as the…

  3. Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

    DEFF Research Database (Denmark)

    Christiansen, Elisabeth; Due-Hansen, Maria E; Urban, Christian

    2012-01-01

    FFA1 (GPR40) is a new target for treatment of type 2 diabetes. We recently identified the potent FFA1 agonist TUG-469 (5). Inspired by the structurally related TAK-875, we explored the effects of a mesylpropoxy appendage on 5. The appendage significantly lowers lipophilicity and improves metaboli...

  4. State FFA Officers' Confidence and Trustworthiness of Biotechnology Information Sources

    Science.gov (United States)

    Wingenbach, Gary J.; Rutherford, Tracy A.

    2007-01-01

    Are state FFA officers' awareness levels of agricultural topics reported in mass media superior to those who do not serve in leadership roles? The purpose of this study was to determine elected state FFA officers' awareness of biotechnology, and their confidence and trust of biotechnology information sources. Descriptive survey methods were used…

  5. An Examination of Middle School Agricultural Education and FFA Programs: Survey Results from State FFA Executive Secretaries.

    Science.gov (United States)

    Rossetti, Rosemarie; McCaslin, N. L.

    A study collected information from 52 of the 53 state Future Farmers of America (FFA) executive secretaries who were sent questionnaires on middle school student enrollment in agricultural education and membership in the national FFA organization. Results showed that 30 states have agricultural education programs in the middle school level, with a…

  6. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

    DEFF Research Database (Denmark)

    Ulven, Trond

    2012-01-01

    The deorphanization of the free fatty acid (FFA) receptors FFA1 (GPR40), FFA2 (GPR43), FFA3 (GPR41), GPR84, and GPR120 has made clear that the body is capable of recognizing and responding directly to nonesterified fatty acid of virtually any chain length. Colonic fermentation of dietary fiber pr...

  7. Winning the War: A Historical Analysis of the FFA during World War II

    Science.gov (United States)

    Wolf, Kattlyn J.; Connors, James J.

    2009-01-01

    The United States' participation in World War II affected millions of men, women, and children, both at home and around the world. The war effort also affected the Future Farmers of America (FFA). FFA members, agriculture teachers, and national FFA officers all volunteered to serve their country during the war. Local FFA chapters and individual…

  8. System Security Authorization Agreement (SSAA) for the WIRE Archive and Research Facility

    Science.gov (United States)

    2002-01-01

    The Wide-Field Infrared Explorer (WIRE) Archive and Research Facility (WARF) is operated and maintained by the Department of Physics, USAF Academy. The lab is located in Fairchild Hall, 2354 Fairchild Dr., Suite 2A103, USAF Academy, CO 80840. The WARF will be used for research and education in support of the NASA Wide Field Infrared Explorer (WIRE) satellite, and for related high-precision photometry missions and activities. The WARF will also contain the WIRE preliminary and final archives prior to their delivery to the National Space Science Data Center (NSSDC). The WARF consists of a suite of equipment purchased under several NASA grants in support of WIRE research. The core system consists of a Red Hat Linux workstation with twin 933 MHz PIII processors, 1 GB of RAM, 133 GB of hard disk space, and DAT and DLT tape drives. The WARF is also supported by several additional networked Linux workstations. Only one of these (an older 450 Mhz PIII computer running Red Hat Linux) is currently running, but the addition of several more is expected over the next year. In addition, a printer will soon be added. The WARF will serve as the primary research facility for the analysis and archiving of data from the WIRE satellite, together with limited quantities of other high-precision astronomical photometry data from both ground- and space-based facilities. However, the archive to be created here will not be the final archive; rather, the archive will be duplicated at the NSSDC and public access to the data will generally take place through that site.

  9. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

    OpenAIRE

    Ulven, Trond

    2012-01-01

    The deorphanization of the free fatty acid (FFA) receptors FFA1 (GPR40), FFA2 (GPR43), FFA3 (GPR41), GPR84, and GPR120 has made clear that the body is capable of recognizing and responding directly to nonesterified fatty acid of virtually any chain length. Colonic fermentation of dietary fiber produces high concentrations of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate, a process which is important to health. The phylogenetically related 7-transmembrane (7TM) receptors...

  10. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

    OpenAIRE

    Trond eUlven

    2012-01-01

    The deorphanization of the free fatty acid (FFA) receptors FFA1 (GPR40), FFA2 (GPR43), FFA3 (GPR41), GPR84 and GPR120 made clear that the body is capable of recognizing and responding directly to nonesterified fatty acid of virtually any chain length. Colonic fermentation of dietary fiber produces high concentrations of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate, a process which is important to health. The phylogenetically related 7-transmembrane receptors free fatty...

  11. Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3

    DEFF Research Database (Denmark)

    Hudson, Brian D; Tikhonova, Irina G; Pandey, Sunil K

    2012-01-01

    Free fatty acid receptors 2 and 3 (FFA2 and FFA3) are G protein-coupled receptors for short chain free fatty acids (SCFAs). They respond to the same set of endogenous ligands but with distinct rank-order of potency such that acetate (C2) has been described as FFA2-selective, whereas propionate (C...

  12. Harmonization between a Framework of Multilateral Approaches to Nuclear Fuel Cycle Facilities and Bilateral Nuclear Cooperation Agreements

    Directory of Open Access Journals (Sweden)

    Makiko Tazaki

    2013-09-01

    Full Text Available One of primary challenges for ensuring effective and efficient functions of the multilateral nuclear approaches (MNA to nuclear fuel cycle facilities is harmonization between a MNA framework and existing nuclear cooperation agreements (NCA. A method to achieve such harmonization is to construct a MNA framework with robust non-proliferation characteristics, in order to obtain supplier states’, especially the US’s prior consents for non-supplier states’ certain activities including spent fuel reprocessing, plutonium storages and retransfers of plutonium originated in NCAs. Such robust characteristics can be accomplished by MNA member states’ compliances with International Atomic Energy Agency (IAEA Safeguards, regional safeguards agreements, international conventions, guidelines and recommendations on nuclear non-proliferation, nuclear security, safety, and export control. Those provisions are to be incorporated into an MNA founding agreement, as requirements to be MNA members in relation to NCAs. Furthermore, if an MNA facility is, (1 owned and operated jointly by all MNA member states, (2 able to conclude bilateral NCAs with non-MNA/supplier states as a single legal entity representing its all member states like an international organization, and (3 able to obtain necessary prior consents, stable, smooth, and timely supplies of nuclear fuel and services can be assured among MNA member states. In this paper, the authors will set out a general MNA framework and then apply it to a specific example of Europe Atomic Energy Community (EURATOM and then consider its applicability to the Asian region, where an establishment of an MNA framework is expected to be explored.

  13. Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3*

    Science.gov (United States)

    Hudson, Brian D.; Tikhonova, Irina G.; Pandey, Sunil K.; Ulven, Trond; Milligan, Graeme

    2012-01-01

    Free fatty acid receptors 2 and 3 (FFA2 and FFA3) are G protein-coupled receptors for short chain free fatty acids (SCFAs). They respond to the same set of endogenous ligands but with distinct rank-order of potency such that acetate (C2) has been described as FFA2-selective, whereas propionate (C3) is non-selective. Although C2 was confirmed to be selective for human FFA2 over FFA3, this ligand was not selective between the mouse orthologs. Moreover, although C3 was indeed not selective between the human orthologs, it displayed clear selectivity for mouse FFA3 over mouse FFA2. This altered selectivity to C2 and C3 resulted from broad differences in SCFAs potency at the mouse orthologs. In studies to define the molecular basis for these observations, marked variation in ligand-independent constitutive activity was identified using a [35S]GTPγS assay. The orthologs with higher potency for the SCFAs, human FFA2 and mouse FFA3, displayed high constitutive activity in this assay, whereas the orthologs with lower potency for the agonist ligands, mouse FFA2 and human FFA3, did not. Sequence alignments of the second extracellular loop identified single negatively charged residues in FFA2 and FFA3 not conserved between species and predicted to form ionic lock interactions with arginine residues within the FFA2 or FFA3 agonist binding pocket to regulate constitutive activity and SCFA potency. Reciprocal mutation of these residues between species orthologs resulted in the induction (or repression) of constitutive activity and in most cases also yielded corresponding changes in SCFA potency. PMID:23066016

  14. Characterising pharmacological ligands to study the long chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

    DEFF Research Database (Denmark)

    Milligan, G; Alvarez-Curto, E; Watterson, K R

    2015-01-01

    control of blood glucose and improve tissue insulin sensitivity, both receptors are being studied as potential therapeutic targets for the control of type II diabetes. Furthermore, genetic and systems biology studies in both humans and mouse models link FFA4 to diabetes and obesity. Although activated...... of the sphingosine 1 phosphate receptor S1P1 . Screening and subsequent medicinal chemistry programmes have developed a number of FFA1 selective agonists that are effective in promoting insulin secretion in a glucose concentration-dependent manner, and in lowering blood glucose levels. However, the recent...... termination of phase III clinical trials employing TAK-875/Fasiglifam has caused a setback and raises important questions over the exact nature and mechanistic causes of the problems. Progress in the identification and development of highly FFA4-selective pharmacological tools has been less rapid and several...

  15. Identifying Quality Indicators of SAE and FFA: A Delphi Approach

    Science.gov (United States)

    Jenkins, Charles Cordell, III; Kitchel, Tracy

    2009-01-01

    The purpose of this study was to determine quality indicators for SAE and FFA according to 36 experts across the United States. This is a part of a larger study looking at all components of the traditional three-circle model. The study utilized the Delphi technique to garner expert opinion about quality indicators in Agricultural Education. For…

  16. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

    Science.gov (United States)

    Ulven, Trond

    2012-01-01

    The deorphanization of the free fatty acid (FFA) receptors FFA1 (GPR40), FFA2 (GPR43), FFA3 (GPR41), GPR84, and GPR120 has made clear that the body is capable of recognizing and responding directly to nonesterified fatty acid of virtually any chain length. Colonic fermentation of dietary fiber produces high concentrations of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate, a process which is important to health. The phylogenetically related 7-transmembrane (7TM) receptors free fatty acid receptor 2 (FFA2) and FFA3 are activated by these SCFAs, and several lines of evidence indicate that FFA2 and FFA3 mediate beneficial effects associated with a fiber-rich diet, and that they may be of interest as targets for treatment of inflammatory and metabolic diseases. FFA2 is highly expressed on immune cells, in particular neutrophils, and several studies suggest that the receptor plays a role in diseases involving a dysfunctional neutrophil response, such as inflammatory bowel disease (IBD). Both FFA2 and FFA3 have been implicated in metabolic diseases such as type 2 diabetes and in regulation of appetite. More research is however required to clarify the potential of the receptors as drug targets and establish if activation or inhibition would be the preferred mode of action. The availability of potent and selective receptor modulators is a prerequisite for these studies. The few modulators of FFA2 or FFA3 that have been published hitherto in the peer-reviewed literature in general have properties that make them less than ideal as such tools, but published patent applications indicate that better tool compounds might soon become available which should enable studies critical to validate the receptors as new drug targets. PMID:23060857

  17. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).

    Science.gov (United States)

    Sparks, Steven M; Chen, Grace; Collins, Jon L; Danger, Dana; Dock, Steven T; Jayawickreme, Channa; Jenkinson, Stephen; Laudeman, Christopher; Leesnitzer, M Anthony; Liang, Xi; Maloney, Patrick; McCoy, David C; Moncol, David; Rash, Vincent; Rimele, Thomas; Vulimiri, Padmaja; Way, James M; Ross, Sean

    2014-07-15

    The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39. The in vitro profile of compounds 8 and 39 is presented herein.

  18. A Fall in Plasma Free Fatty Acid (FFA) Level Activates the Hypothalamic-Pituitary-Adrenal Axis Independent of Plasma Glucose: Evidence for Brain Sensing of Circulating FFA

    Science.gov (United States)

    Oh, Young Taek; Oh, Ki-Sook; Kang, Insug

    2012-01-01

    The brain responds to a fall in blood glucose by activating neuroendocrine mechanisms for its restoration. It is unclear whether the brain also responds to a fall in plasma free fatty acids (FFA) to activate mechanisms for its restoration. We examined whether lowering plasma FFA increases plasma corticosterone or catecholamine levels and, if so, whether the brain is involved in these responses. Plasma FFA levels were lowered in rats with three independent antilipolytic agents: nicotinic acid (NA), insulin, and the A1 adenosine receptor agonist SDZ WAG 994 with plasma glucose clamped at basal levels. Lowering plasma FFA with these agents all increased plasma corticosterone, but not catecholamine, within 1 h, accompanied by increases in plasma ACTH. These increases in ACTH or corticosterone were abolished when falls in plasma FFA were prevented by Intralipid during NA or insulin infusion. In addition, the NA-induced increases in plasma ACTH were completely prevented by administration of SSR149415, an arginine vasopressin receptor antagonist, demonstrating that the hypothalamus is involved in these responses. Taken together, the present data suggest that the brain may sense a fall in plasma FFA levels and activate the hypothalamic-pituitary-adrenal axis to increase plasma ACTH and corticosterone, which would help restore FFA levels. Thus, the brain may be involved in the sensing and control of circulating FFA levels. PMID:22669895

  19. Uranium-Loaded Water Treatment Resins: 'Equivalent Feed' at NRC and Agreement State-Licensed Uranium Recovery Facilities - 12094

    Energy Technology Data Exchange (ETDEWEB)

    Camper, Larry W.; Michalak, Paul; Cohen, Stephen; Carter, Ted [Nuclear Regulatory Commission (United States)

    2012-07-01

    Community Water Systems (CWSs) are required to remove uranium from drinking water to meet EPA standards. Similarly, mining operations are required to remove uranium from their dewatering discharges to meet permitted surface water discharge limits. Ion exchange (IX) is the primary treatment strategy used by these operations, which loads uranium onto resin beads. Presently, uranium-loaded resin from CWSs and mining operations can be disposed as a waste product or processed by NRC- or Agreement State-licensed uranium recovery facilities if that licensed facility has applied for and received permission to process 'alternate feed'. The disposal of uranium-loaded resin is costly and the cost to amend a uranium recovery license to accept alternate feed can be a strong disincentive to commercial uranium recovery facilities. In response to this issue, the NRC issued a Regulatory Issue Summary (RIS) to clarify the agency's policy that uranium-loaded resin from CWSs and mining operations can be processed by NRC- or Agreement State-licensed uranium recovery facilities without the need for an alternate feed license amendment when these resins are essentially the same, chemically and physically, to resins that licensed uranium recovery facilities currently use (i.e., equivalent feed). NRC staff is clarifying its current alternate feed policy to declare IX resins as equivalent feed. This clarification is necessary to alleviate a regulatory and financial burden on facilities that filter uranium using IX resin, such as CWSs and mine dewatering operations. Disposing of those resins in a licensed facility could be 40 to 50 percent of the total operations and maintenance (O and M) cost for a CWS. Allowing uranium recovery facilities to treat these resins without requiring a license amendment lowers O and M costs and captures a valuable natural resource. (authors)

  20. Program management assessment of Federal Facility Compliance Agreement regarding CAA-40 C.F.R. Part 61, Subpart H at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    An assessment of Los Alamos National Laboratory`s management system related to facility compliance with an element of the Clean Air Act was performed under contract by a team from Northern Arizona University. More specifically, a Federal Facilities Compliance Agreement (FFCA) was established in 1996 to bring the Laboratory into compliance with emissions standards of radionuclides, commonly referred to as Rad/NESHAP. In the fall of 1996, the four-person team of experienced environmental managers evaluated the adequacy of relevant management systems to implement the FFCA provisions. The assessment process utilized multiple procedures including document review, personnel interviews and re-interviews, and facility observations. The management system assessment was completed with a meeting among team members, Laboratory officials and others on November 1, 1996 and preparation of an assessment report.

  1. A service-based SLA (Service Level Agreement) for the RACF (RHIC and ATLAS computing facility) at brookhaven national lab

    Science.gov (United States)

    Karasawa, Mizuka; Chan, Tony; Smith, Jason

    2010-04-01

    The RACF provides computing support to a broad spectrum of scientific programs at Brookhaven. The continuing growth of the facility, the diverse needs of the scientific programs and the increasingly prominent role of distributed computing requires the RACF to change from a system to a service-based SLA with our user communities. A service-based SLA allows the RACF to coordinate more efficiently the operation, maintenance and development of the facility by mapping out a matrix of system and service dependencies and by creating a new, configurable alarm management layer that automates service alerts and notification of operations staff. This paper describes the adjustments made by the RACF to transition to a service-based SLA, including the integration of its monitoring software, alarm notification mechanism and service ticket system at the facility to make the new SLA a reality.

  2. Examining Camper Learning Outcomes and Knowledge Retention at Oklahoma FFA Leadership Camp

    Science.gov (United States)

    Brown, Nicholas R.; Terry, Robert, Jr.; Kelsey, Kathleen D.

    2014-01-01

    The National FFA Organization is committed to providing non-formal learning activities focusing on leadership education. Summer camps are a major component of FFA activities and concentrate on personal growth, leadership development, and recreational activities for youth. This repeated measures study determined the level of cognitive gain and the…

  3. A Status Report on Middle Grade Agricultural Education and FFA Programs in the United States.

    Science.gov (United States)

    Rossetti, Rosemarie; McCaslin, N. L.

    1994-01-01

    Census of 52 Future Farmers of America (FFA) executive secretaries found the following: 30 states have middle-grade agricultural education; 19 have middle-grade FFA membership; 14 have a core agriculture curriculum; 17 have state-level competitions; most do not favor national middle-grade competitions; and few disadvantages apart from potential…

  4. Barriers to Participation in the National FFA Organization According to Urban Agriculture Students

    Science.gov (United States)

    Martin, Michael J.; Kitchel, Tracy

    2014-01-01

    Urban youth engaged in after-school organizations have more positive attributes compared to their unengaged contemporaries. The FFA is one particular intra-curricular organization with after-school components; yet, urban students do not participate in FFA at the same levels as rural students. The purpose of this descriptive study was to explore…

  5. Pathways to privatization: Issues and concerns on the road to privatization of facilities on the Oak Ridge Reservation

    Energy Technology Data Exchange (ETDEWEB)

    Yard, C.R.

    1997-02-01

    Through the cooperative efforts of the State of Tennessee and the Department of Energy, privatization of the first federal facility on the Oak Ridge Reservation has become a reality. One section of the facility has been transferred to private industry while the other portion of the facility remains in control of the government`s prime contractor. Due to this unusual arrangement, there are significant issues to be dealt with. This paper will describe the issues and concerns expressed by the participants in the process. The State of Tennessee`s efforts are primarily conducted by two Divisions of the Department of Environment and Conservation. These two Divisions (Radiological Health and DOE-Oversight) share the responsibility of assuring that the privatization effort is properly implemented. This shared responsibility is divided along distinct lines by the Divisions respective regulatory and nonregulatory functions. DOE responsibilities during transfer are delineated in the Federal Facilities Agreement (FFA) section XLIII. Property Transfer. The FFA states (in part) that {open_quotes}the DOE shall include notice of this agreement in any document transferring ownership or operation of the site to any subsequent owner and/or operator of any portion of the site and shall notify EPA and TDEC of any such sale or Transfer.{close_quotes} The FFA continues by stating that {open_quotes}No change in ownership of the site or any portionthereof or notice pursuant to Section 120 (h) (3) (B) of CERCLA, 42 U.S.C. {delta} 9620 (h) (3) (B), shall relieve the DOE of its obligation to perform pursuant to this agreement. No change of ownership of the site or any portion thereof shall be consummated by the DOE without provision for continued maintenance of any containment system, treatment system, or other response action(s) installed or implemented pursuant to this Agreement. This provision does not relieve the DOE of its obligation under 40 C.F.R. Part 270.{close_quotes}

  6. GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    DEFF Research Database (Denmark)

    Ekberg, Jeppe H; Pedersen, Maria Hauge; Kristensen, Line V

    2016-01-01

    expressed and highly enriched in FACS-purified GLP-1 and GIP cells isolated from transgenic reporter mice. In vivo, the triglyceride-induced increase in plasma GIP was significantly reduced in FFA1 deficient mice (to 34% - mean of four experiments each with 8-10 animals), in GPR119 deficient mice (to 24...... %) and in FFA1/FFA4 double deficient mice (to 15%) but not in FFA4 deficient mice. The triglyceride-induced increase in plasma GLP-1 was only significantly reduced in the GPR119 deficient and the FFA1/FFA4 double deficient mice, but not in the FFA1 and FFA4 deficient mice. In mouse colonic crypt cultures...

  7. FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways.

    Science.gov (United States)

    Jiao, Ping; Ma, Jie; Feng, Bin; Zhang, Hao; Diehl, J Alan; Chin, Y Eugene; Yan, Weiqun; Xu, Haiyan

    2011-03-01

    Free-fatty acids (FFAs) are well-characterized factor for causing production of inflammatory factors and insulin resistance in adipocytes. Using cultured adipocytes, we demonstrate that FFAs can activate endoplasmic reticulum (ER) stress pathway by examination of ER stress sensor activation and marker gene expression. Chemical chaperone tauroursodeoxycholic acid (TUDCA) can reduce FFA-induced adipocyte inflammation and improve insulin signaling whereas overexpression of spliced X-box protein 1 (XBP-1s) only attenuates FFA-induced inflammation. PKR-like eukaryotic initiation factor 2α kinase (PERK) is one of the three major ER stress sensor proteins and deficiency of PERK alleviates FFA-induced inflammation and insulin resistance. The key downstream target of FFA-induced ER stress is IκB kinase β (IKKβ), a master kinase for regulating expression of inflammatory genes. Deficiency of PERK attenuates FFA-induced activation of IKKβ and deficiency of IKKβ alleviates FFA-induced inflammation and insulin resistance. Consistently, overexpression of IKKβ in 3T3-L1 CAR adipocytes causes inflammation and insulin resistance. In addition, IKKβ overexpression has profound effect on adipocyte lipid metabolism, including inhibition of lipogenesis and promotion of lipolysis. Furthermore, increased endogenous IKKβ expression and activation is also observed in isolated primary adipocytes from mice injected with lipids or fed on high-fat diet (HFD) acutely. These results indicate that ER stress pathway is a key mediator for FFA-induced inflammation and insulin resistance in adipocytes with PERK and IKKβ as the critical signaling components.

  8. South Carolina Department of Health and Environmental Control federal facility agreement. Annual progress report, fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Hucks, R.L.

    1996-01-30

    South Carolina Department of Health and Environmental Control (SCDHEC) reviewed 105 primary documents during fiscal year 1995 (October 1, 1994 through September 30, 1995). The primary documents reviewed consisted of 27 RCRA Facility Investigation/Remedial Investigation (RFI/RI) workplans, 13 RFI/RI Reports, 12 Baseline Risk Assessments (BRA`s), 27 Site Evaluation (SE) Reports, 8 Proposed Plans, 5 Record of Decisions (ROD`s), 6 Remedial Design Workplans, 6 Remedial Action Workplans and 10 miscellaneous primary documents. Numerous other administrative duties were conducted during the reporting period that are not accounted for above. These included, but were not limited to, extension requests, monitoring well approvals, and Treatability Studies. The list of outgoing correspondence from SCDHEC to the Department of Energy (DOE) and Westinghouse Savannah River Company (WSRC) is attached.

  9. Functional Fit Approach (FFA) for Density of States method: SU(3) spin system and SU(3) lattice gauge theory with static quarks

    CERN Document Server

    Giuliani, Mario

    2016-01-01

    We apply a recently developed variant of the Density of States (DoS) method, the so-called Functional Fit Approach (FFA) to two different models: the SU(3) spin model and SU(3) lattice gauge theory with static quarks. Both models can be derived from QCD and inherit the complex action problem at finite density. We discuss the implementation of DoS FFA in the two models and compute observables related to the particle density. For the SU(3) spin model we show that the results are in good agreement with the results from a Monte Carlo simulation in the dual formulation, which is free of the complex action problem. For the case of SU(3) lattice gauge theory with static quarks we present first results for the particle number as a function of the coupling for different values of the chemical potential.

  10. Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages.

    Science.gov (United States)

    Im, Dong-Soon

    2016-08-15

    Omega-3 polyunsaturated fatty acids (n-3 PUFAs), which are plentiful in fish oil, have been known for decades to be beneficial functional nutrients in different disease states. GPR120 is a G protein-coupled receptor for long-chain unsaturated fatty acids, including n-3 PUFAs, and was recently renamed free fatty acid receptor 4 (FFA4). Studies on FFA4-deficient mice and the development of specific pharmacological tools have started to unravel the functions of FFA4 associated with the actions of n-3 PUFAs in obesity, type 2 diabetes, and inflammation-related diseases. Here, the state of the art regarding the roles and functions of FFA4 and n-3 PUFA in macrophages are reviewed from the pharmacological perspective. In particular, the functions of n-3 PUFA on the anti-inflammatory M2 phenotypes of macrophages in different organs, such as, adipose tissues and liver, are discussed along with future research directions.

  11. The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120)

    OpenAIRE

    Hudson, Brian D.; Shimpukade, Bharat; Milligan, Graeme; Ulven, Trond

    2014-01-01

    The long-chain fatty acid receptor FFA4(previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease. The current study examines for the first time the detailed mode of binding of both a long-chain fatty acid and synthetic agonist ligands at FFA4 by integrating molecular modeling, receptor mutagenesis, and ligand structure-activity relationship approaches in an iterative format. In doing so, residues required for binding of fat...

  12. [Profile of free fatty acids (FFA) in serum of young Colombians with obesity and metabolic syndrome].

    Science.gov (United States)

    Bermudez, J A; Velásquez, C M

    2014-12-01

    Obesity produces greater circulation of free fatty acids (FFA). In adults, the FFA composition changes in states of obesity; in adolescents, the results are contradictory. This study compare the FFA profile of obese youth with and without Metabolic Syndrome (MetS) and explore the association between FFA and metabolic alterations of obesity and MetS. A cross-sectional study with 96 young people between 10 and 18 years old was divided into three groups: 1) obese youth with MetS, 2) obese youth without MetS; and 3) adequate weight (AW), matched according to age, gender, pubertal maturation and socioeconomic stratum. The nutritional status was classified according to the body-mass index (BMI), according to the World Health Organization 2007 (WHO, 2007); the waist circumference (WC), adiposity, lipid profile, highly-sensitive reactive C protein (hsRCP), glucose, insulin and insulin resistance (IR), according to the homeostatic model assessment (HOMA Calculator Version 2.2.2). The FFA serum concentration was determined by gas chromatography. Both obese groups had higher adiposity, inflamation (hsRCP), FFA totals and frequency palmitoleic-16:Jn7, compared to AW. The obese with MetS presented more metabolic alterations, a greater amount of dihomo-γ-linolenic (DHGL-20:3n6) and a 20:3n6/18:2n6 relation, indicative of increased activity of A6 desaturase (D6D). The FFA totals, palmitoleic-l6:1n7, DHGL-20:3n6, D6D activity and hsRCP significantly correlated with variables of adiposity, IR and triglicerides. The results in obese with MetS corroborate the association among central obesity, inflammation and increased lipolysis in visceral adipose tissue and metabolic alterations.

  13. Omega-3 polyunsaturated fatty acids accelerate airway repair by activating FFA4 in club cells.

    Science.gov (United States)

    Lee, Kyoung-Pil; Park, Soo-Jin; Kang, Saeromi; Koh, Jung-Min; Sato, Koichi; Chung, Hae Young; Okajima, Fumikazu; Im, Dong-Soon

    2017-03-17

    A GPCR named FFA4 (also known as GPR120) was found to act as a GPCR for omega-3 polyunsaturated fatty acids. Its expression has been reported in lung epithelial club cells. The authors investigated whether supplementation of the omega-3 fatty acids benefits lung health. Omacor® (7.75 mg kg-1), clinically prescribed preparation of omega-3 fatty acids and FFA4-knockout mice were utilized in a naphthalene-induced mouse model of acute airway injury (one injection of 30 mg kg-1, i.p.). Naphthalene injection induced complete destruction of bronchiolar epithelial cells within a day. Appearance of bronchiolar epithelial cells was observed after 21 days in control mice. It was found, however, that supplementation of omacor accelerated the recovery. The appearance of bronchiolar epithelial cells was observed between 7 and 14 days after naphthalene injury in omacor-treated mice. In isolated club cells, omega-3 fatty acids were found to stimulate cell proliferation and migration but to inhibit cell differentiation. Using pharmacological tools and FFA4-knockout mice, FFA4 was found to be responsible for omega-3 fatty acids-induced proliferation in vitro in club cells. Furthermore, accelerated recovery from naphthalene-induced airway injury in omacor-treated mice was not observed in FFA4-knockout mice in vivo. Present findings indicate that omega-3 fatty acids-induced proliferation of bronchiole epithelial cells through FFA4 is responsible for omacor-induced accelerated recovery from airway injury. Therefore, intermittent administration of omacor needs to be tested for acute airway injury, because omega-3 fatty acids stimulate proliferation but inhibits differentiation of club cells.

  14. STUDY ON OBESITY RELATED FACTORS: FFA, LEPTIN AND ADIPONECTIN IN SUBJECTS WITH VARYING GLUCOSE TOLERANCE

    Institute of Scientific and Technical Information of China (English)

    顾卫琼; 洪洁; 张翼飞; 宁光; 陈名道; 唐金凤

    2005-01-01

    Objective To study the fasting serum levels of obesity related factors: FFA, leptin and adiponectin in subjects with varying glucose tolerance and their relationship with BMI, insulin sensitivity index and islet beta-cell function. Methods Serum levels of FFA, leptin and adiponectin in 24 normal, 32 simple obese, 34IGT and 36 T2DM subjects were measured by ACS-ACOD assay or RIA. Results The serum levels of leptin and FFA in three groups: simple obese, IGT and DM were much higher than those in normal control (P<0. 001 ). In contrast, serum level of adiponectin of simple obese, IGT and DM groups were significant lower than that of normal control, among them DM subjects had the lowest level ( P<0. 001 ). Correlation analysis showed that FFA was positively correlated to BMI, WHR, FBG, fasting insulin level and negatively correlated to SI; adiponectin was negatively correlated to BMI, WHR, FBG, PBG, but positively correlated to SI and AIRg; and leptin was positively correlated to BMI, fasting insulin and AIRg when negatively correlated to FBG and SI. None of them was correlated to age.Conclusion Subjects with insulin resistance have high serum FFA and leptin levels but low serum adiponectin level.With the glucose tolerance deterioration, serum FFA level increases much higher while the adiponectin deceases much lower. Unlike insulin, none of these obesity related factors can be used as the simple indicating or determining factor of SI, though each of them, to different extent, takes part in the development of insulin resistance.

  15. Leadership and Personal Development Abilities Possessed by High School Seniors Who Are FFA Members in Superior FFA Chapters, Non-Superior Chapters, and by Seniors Who Were Never Enrolled in Vocational Agriculture.

    Science.gov (United States)

    Ricketts, Samuel Clifton

    The purpose of this study was to describe the leadership and personal development abilities possessed by four groups of male high school seniors. These groups were those high school seniors who participated in high quality (superior) Future Farmers of America (FFA) chapters and low quality (non-superior) FFA chapters and those from schools with…

  16. Environmental Management Waste Management Facility Waste Lot Profile 155.5 for K-1015-A Laundry Pit, East Tennessee Technology Park Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel Jacobs, Raymer J.E.

    2008-06-12

    In 1989, the Oak Ridge Reservation (ORR), which includes the East Tennessee Technology Park (ETTP), was placed on the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) National Priorities List. The Federal Facility Agreement (FFA) (DOE 1992), effective January 1, 1992, now governs environmental restoration activities conducted under CERCLA at the ORR. Following signing of the FFA, U.S. Department of Energy (DOE), U.S. Environmental Protection Agency (EPA), and the state of Tennessee signed the Oak Ridge Accelerated Cleanup Plan Agreement on June 18, 2003. The purpose of this agreement is to define a streamlined decision-making process to facilitate the accelerated implementation of cleanup, to resolve ORR milestone issues, and to establish future actions necessary to complete the accelerated cleanup plan by the end of fiscal year 2008. While the FFA continues to serve as the overall regulatory framework for remediation, the Accelerated Cleanup Plan Agreement supplements existing requirements to streamline the decision-making process. The disposal of the K-1015 Laundry Pit waste will be executed in accordance with the 'Record of Decision for Soil, Buried Waste, and Subsurface Structure Actions in Zone, 2, East Tennessee Technology Park, Oak Ridge, Tennessee' (DOB/ORAH-2161&D2) and the 'Waste Handling Plan for the Consolidated Soil and Waste Sites with Zone 2, East Tennessee Technology Park, Oak Ridge, Tennessee' (DOE/OR/01-2328&D1). This waste lot consists of a total of approximately 50 cubic yards of waste that will be disposed at the Environmental Management Waste Management Facility (EMWMF) as non-containerized waste. This material will be sent to the EMWMF in dump trucks. This profile is for the K-1015-A Laundry Pit and includes debris (e.g., concrete, metal rebar, pipe), incidental soil, plastic and wood, and secondary waste (such as plastic sheeting, hay bales and other erosion control materials, wooden

  17. Preliminary engineering report waste area grouping 5, Old Hydrofracture Facility Tanks content removal project, Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The Superfund Amendments and Reauthorization Act of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) requires a Federal Facilities Agreement (FFA) for federal facilities placed on the National Priorities List. The Oak Ridge Reservation was placed on that list on December 21, 1989, and the agreement was signed in November 1991 by the U.S. Department of Energy (DOE) Oak Ridge Operations Office, the U.S. Environmental Protection Agency (EPA) Region IV, and the Tennessee Department of Environment and Conservation (TDEC). The effective date of the FFA is January 1, 1992. One objective of the FFA is to ensure that liquid low-level waste (LLLW) tanks that are removed from service are evaluated and remediated through the CERCLA process. Five inactive LLLW tanks, designated T-1, T-2, T-3, T-4, and T-9, located at the Old Hydrofracture (OHF) Facility in the Melton Valley area of Oak Ridge National Laboratory (ORNL) have been evaluated and are now entering the remediation phase. As a precursor to final remediation, this project will remove the current liquid and sludge contents of each of the five tanks (System Requirements Document, Appendix A). It was concluded in the Engineering Evaluation/Cost Analysis [EE/CA] for the Old Hydrofracture Facility Tanks (DOE 1996) that sluicing and pumping the contaminated liquid and sludge from the five OHF tanks was the preferred removal action. Evaluation indicated that this alternative meets the removal action objective and can be effective, implementable, and cost-effective. Sluicing and removing the tank contents was selected because this action uses (1) applicable experience, (2) the latest information about technologies and techniques for removing the wastes from the tanks, and (3) activities that are currently acceptable for storage of transuranic (TRU) mixed waste.

  18. Adiponectin concentrations increase during acute FFA elevation in humans treated with rosiglitazone.

    Science.gov (United States)

    Krzyzanowska, K; Mittermayer, F; Krugluger, W; Roden, M; Schernthaner, G; Wolzt, M

    2007-10-01

    The adipocytokine adiponectin is released by adipocytes upon activation of the peroxisome proliferator-activated receptor gamma (PPAR gamma). PPAR gamma has binding sites for thiazolidinediones and free fatty acids (FFAs). To evaluate if adiponectin serum concentrations are synergistically regulated by FFAs and thiazolidinediones IN VIVO plasma FFAs were acutely elevated in healthy subjects pre-treated with rosiglitazone or placebo. Sixteen healthy male subjects (23-37 years) were included in this double-blind, randomized, placebo-controlled parallel-group study. Rosiglitazone 8 mg or placebo was administered daily for 21 days. On the last day plasma FFA concentrations were increased by an intravenous triglyceride/heparin infusion. Blood for determination of adiponectin, C-reactive protein (CRP), leptin, resistin, FFAs, glucose, and insulin was drawn at baseline and on day 21 before and after 5 hours of triglyceride/heparin infusion. Adiponectin concentrations increased and FFA levels decreased in subjects receiving rosiglitazone (all p<0.05 VS. baseline). Lipid infusion significantly increased FFA plasma concentrations, with an attenuated elevation in rosiglitazone-treated subjects. However, adiponectin concentrations were only increased in subjects on rosiglitazone (p=0.018 VS. before lipid infusion), but not in controls. Leptin increased during lipid infusion in subjects receiving placebo but not in those on rosiglitazone. CRP and resistin were not affected by rosiglitazone or FFAs. The acute increase in circulating adiponectin concentrations during acutely elevated FFA depends on PPAR gamma activation in healthy subjects.

  19. Separation of FFA from Partially Hydrogenated Soybean Oil Hydrolysate by Means of Membrane Processing

    DEFF Research Database (Denmark)

    Jala, Ram Chandra Reddy; Guo, Zheng; Xu, Xuebing

    2011-01-01

    Different types of commercial porous and non-porous polymeric membranes have been investigated for their capabilities to separate free fatty acids (FFA) from hydrolysate of partially hydrogenated soybean oil. A regenerated cellulose (RC, PLAC) membrane exhibited the most prominent difference...

  20. The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)*

    Science.gov (United States)

    Hudson, Brian D.; Shimpukade, Bharat; Milligan, Graeme; Ulven, Trond

    2014-01-01

    The long-chain fatty acid receptor FFA4 (previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease. This study examines for the first time the detailed mode of binding of both long-chain fatty acid and synthetic agonist ligands at FFA4 by integrating molecular modeling, receptor mutagenesis, and ligand structure-activity relationship approaches in an iterative format. In doing so, residues required for binding of fatty acid and synthetic agonists to FFA4 have been identified. This has allowed for the refinement of a well validated model of the mode of ligand-FFA4 interaction that will be invaluable in the identification of novel ligands and the future development of this receptor as a therapeutic target. The model reliably predicted the effects of substituent variations on agonist potency, and it was also able to predict the qualitative effect of binding site mutations in the majority of cases. PMID:24860101

  1. Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer

    DEFF Research Database (Denmark)

    Christiansen, Elisabeth; Hudson, Brian D; Hansen, Anders Højgaard;

    2016-01-01

    The free fatty acid receptor 1 (FFA1/GPR40) is a potential target for treatment of type 2 diabetes. Although several potent agonists have been described, there remains a strong need for suitable tracers to interrogate ligand binding to this receptor. We address this by exploring fluorophore-tethe...

  2. Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120)

    DEFF Research Database (Denmark)

    Hansen, Steffen V F; Ulven, Trond

    2017-01-01

    The free fatty acid receptor 4 (FFA4), also known as GPR120, is a G protein-coupled receptor that is activated by long-chain fatty acids and that has been associated with regulation of appetite, release of insulin controlling hormones, insulin sensitization, anti-inflammatory and potentially anti...

  3. The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120)

    DEFF Research Database (Denmark)

    Hudson, Brian D; Shimpukade, Bharat; Milligan, Graeme

    2014-01-01

    The long-chain fatty acid receptor FFA4 (previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease. This study examines for the first time the detailed mode of binding of both long-chain fatty acid and synthetic agonist ligands ...

  4. Developing and testing the density of states FFA method in the SU(3) spin model

    CERN Document Server

    Giuliani, Mario; Törek, Pascal

    2016-01-01

    The Density of States Functional Fit Approach (DoS FFA) is a recently proposed modern density of states technique suitable for calculations in lattice field theories with a complex action problem. In this article we present an exploratory implementation of DoS FFA for the SU(3) spin system at finite chemical potential $\\mu$ - an effective theory for the Polyakov loop. This model has a complex action problem similar to the one of QCD but also allows for a dual simulation in terms of worldlines where the complex action problem is solved. Thus we can compare the DoS FFA results to the reference data from the dual simulation and assess the performance of the new approach. We find that the method reproduces the observables from the dual simulation for a large range of $\\mu$ values, including also phase transitions, illustrating that DoS FFA is an interesting approach for exploring phase diagrams of lattice field theories with a complex action problem.

  5. Effects of Acute Supramaximal Cycle Exercise on Plasma FFA Concentration in Obese Adolescent Boys.

    Directory of Open Access Journals (Sweden)

    Georges Jabbour

    Full Text Available The aims of the present study are 1 to evaluate the free fatty acid (FFA profile and 2 to determine the relative anaerobic and aerobic contributions to total energy consumption during repeated supramaximal cycling bouts (SCE in adolescent boys with different body weight statuses.Normal-weight (NW, overweight (OW, and obese (OB adolescent boys (n =15 per group completed a SCE sessions consisted of 6 x 6s maximal sprints with 2 min of passive rest between each repetition. Plasma FFA levels were determined at rest, immediately after a 10 min warm-up, and immediately at the end of SCE. The anaerobic and aerobic contributions (% were measured via repeated SCE bouts. Insulin resistance was calculated using the homoeostatic model assessment (HOMA-IR index.The FFA concentrations measured immediately after SCE were higher in the OB group than in the OW and NW (p<0.01 and p<0.01, respectively groups. Moreover, the anaerobic contributions to SCE were significantly lower in obese adolescents (p<0.01 and decreased significantly during the 2nd, 3rd and 4th repetitions. The FFA levels were significantly associated with the HOMA-IR index and aerobic contribution among adolescent boys (r=0.83 and r=0.91, respectively, p<0.01.In contrast to the NW and OW groups, there is an increase in lipid mobilization and sift to aerobic energy metabolism during SCE in the OB group.

  6. Developing and testing the density of states FFA method in the SU(3) spin model

    Science.gov (United States)

    Giuliani, Mario; Gattringer, Christof; Törek, Pascal

    2016-12-01

    The Density of States Functional Fit Approach (DoS FFA) is a recently proposed modern density of states technique suitable for calculations in lattice field theories with a complex action problem. In this article we present an exploratory implementation of DoS FFA for the SU(3) spin system at finite chemical potential μ - an effective theory for the Polyakov loop. This model has a complex action problem similar to the one of QCD but also allows for a dual simulation in terms of worldlines where the complex action problem is solved. Thus we can compare the DoS FFA results to the reference data from the dual simulation and assess the performance of the new approach. We find that the method reproduces the observables from the dual simulation for a large range of μ values, including also phase transitions, illustrating that DoS FFA is an interesting approach for exploring phase diagrams of lattice field theories with a complex action problem.

  7. Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4

    DEFF Research Database (Denmark)

    Watterson, Kenneth R; Hansen, Steffen V F; Hudson, Brian D

    2017-01-01

    anticancer drugs suggests that a novel close chemical analog of AH-7614 devoid of FFA4 activity, 4-methyl-N-(9H-xanthen-9-yl)benzamide (TUG-1387), will also provide a useful control compound for future studies assessing FFA4 function. Using TUG-1387 alongside AH-7614, we show that endogenous activation...

  8. A Nationwide Examination of Middle School Enrollment in Agricultural Education and Membership in the National FFA Organization.

    Science.gov (United States)

    Rossetti, Rosemarie; And Others

    The purpose of this study was to determine the status of middle and junior high school agricultural education and FFA (Future Farmers of America) programs. In spring 1991. questionnaires were sent to all state FFA Executive Secretaries (n=53); 52 returned questionnaires. Three teachers in each of 9 states identified as having middle or junior high…

  9. Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor*

    Science.gov (United States)

    Hudson, Brian D.; Due-Hansen, Maria E.; Christiansen, Elisabeth; Hansen, Anna Mette; Mackenzie, Amanda E.; Murdoch, Hannah; Pandey, Sunil K.; Ward, Richard J.; Marquez, Rudi; Tikhonova, Irina G.; Ulven, Trond; Milligan, Graeme

    2013-01-01

    FFA2 is a G protein-coupled receptor that responds to short chain fatty acids and has generated interest as a therapeutic target for metabolic and inflammatory conditions. However, definition of its functions has been slowed by a dearth of selective ligands that can distinguish it from the closely related FFA3. At present, the only selective ligands described for FFA2 suffer from poor potency, altered signaling due to allosteric modes of action, or a lack of function at non-human orthologs of the receptor. To address the need for novel selective ligands, we synthesized two compounds potentially having FFA2 activity and examined the molecular basis of their function. These compounds were confirmed to be potent and selective orthosteric FFA2 agonists. A combination of ligand structure-activity relationship, pharmacological analysis, homology modeling, species ortholog comparisons, and mutagenesis studies were then employed to define the molecular basis of selectivity and function of these ligands. From this, we identified key residues within both extracellular loop 2 and the transmembrane domain regions of FFA2 critical for ligand function. One of these ligands was active with reasonable potency at rodent orthologs of FFA2 and demonstrated the role of FFA2 in inhibition of lipolysis and glucagon-like peptide-1 secretion in murine-derived 3T3-L1 and STC-1 cell lines, respectively. Together, these findings describe the first potent and selective FFA2 orthosteric agonists and demonstrate key aspects of ligand interaction within the binding site of FFA2 that will be invaluable in future ligand development at this receptor. PMID:23589301

  10. Determination of SFC, FFA, and equivalent reaction time for enzymatically interestified oils using NIRS

    DEFF Research Database (Denmark)

    Houmøller, Lars P.; Kristensen, Dorthe; Rosager, Helle

    2007-01-01

    that NIRS could be used to replace the traditional methods for determining FFA and SFC in vegetable oils.It was possible to monitor the activity of the immobilized enzyme for interesterification of margarine oils by predicting the equivalent reaction time in a batch reactor from NIR spectra. Root mean...... both fixed bed and batch reactors. Calibrations were developed for quantitative determination of solid fat content (SFC) at 10, 20, 30, 35, and 40 ◦C and free fatty acid (FFA) resulting in root mean square errors of prediction of 1.0, 1.3, 1.4, 1.6, 1.7, and 0.19% (w/w), respectively. The data showed...

  11. Density of States FFA analysis of SU(3) lattice gauge theory at a finite density of color sources

    Science.gov (United States)

    Giuliani, Mario; Gattringer, Christof

    2017-10-01

    We present a Density of States calculation with the Functional Fit Approach (DoS FFA) in SU(3) lattice gauge theory with a finite density of static color sources. The DoS FFA uses a parameterized density of states and determines the parameters of the density by fitting data from restricted Monte Carlo simulations with an analytically known function. We discuss the implementation of DoS FFA and the results for a qualitative picture of the phase diagram in a model which is a further step towards implementing DoS FFA in full QCD. We determine the curvature κ in the μ-T phase diagram and find a value close to the results published for full QCD.

  12. Dietary Fatty Acids and Their Potential for Controlling Metabolic Diseases Through Activation of FFA4/GPR120.

    Science.gov (United States)

    Ulven, Trond; Christiansen, Elisabeth

    2015-01-01

    It is well known that the amount and type of ingested fat impacts the development of obesity and metabolic diseases, but the potential for beneficial effects from fat has received less attention. It is becoming clear that the composition of the individual fatty acids in diet is important. Besides acting as precursors of potent signaling molecules, dietary fatty acids act directly on intracellular and cell surface receptors. The free fatty acid receptor 4 (FFA4, previously GPR120) is linked to the regulation of body weight, inflammation, and insulin resistance and represents a potential target for the treatment of metabolic disorders, including type 2 diabetes and obesity. In this review, we discuss the various types of dietary fatty acids, the link between FFA4 and metabolic diseases, the potential effects of the individual fatty acids on health, and the ability of fatty acids to activate FFA4. We also discuss the possibility of dietary schemes that implement activation of FFA4.

  13. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

    DEFF Research Database (Denmark)

    Hudson, Brian D; Due-Hansen, Maria E; Christiansen, Elisabeth

    2013-01-01

    , species ortholog comparisons and mutagenesis studies were then employed to define the molecular basis of selectivity and function of these ligands. From this, we identified key residues within both extracellular loop 2 (ECL2) and the transmembrane domain (TM) regions of FFA2 critical for ligand function......FFA2 is a G protein-coupled receptor that responds to short chain fatty acids (SCFAs) and has generated interest as a therapeutic target for metabolic and inflammatory conditions. However, definition of its functions has been slowed by a dearth of selective ligands that can distinguish it from...... the closely related FFA3. At present, the only selective ligands described for FFA2 suffer from either poor potency, altered signaling due to allosteric modes of action, or a lack of function at non-human orthologs of the receptor. To address the need for novel selective ligands, we synthesized two compounds...

  14. Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40*

    Science.gov (United States)

    Schmidt, Johannes; Liebscher, Kathrin; Merten, Nicole; Grundmann, Manuel; Mielenz, Manfred; Sauerwein, Helga; Christiansen, Elisabeth; Due-Hansen, Maria E.; Ulven, Trond; Ullrich, Susanne; Gomeza, Jesús; Drewke, Christel; Kostenis, Evi

    2011-01-01

    Among dietary components, conjugated linoleic acids (CLAs) have attracted considerable attention as weight loss supplements in the Western world because they reduce fat stores and increase muscle mass. However, a number of adverse effects are also ascribed to the intake of CLAs such as aggravation of insulin resistance and the risk of developing diabetes. However, the mechanisms accounting for the effects of CLAs on glucose homeostasis are incompletely understood. Herein we provide evidence that CLAs specifically activate the cell surface receptor FFA1, an emerging therapeutic target to treat type 2 diabetes. Using different recombinant cellular systems engineered to stably express FFA1 and a set of diverse functional assays including the novel, label-free non-invasive dynamic mass redistribution technology (Corning® Epic® biosensor), both CLA isomers cis-9, trans-11-CLA and trans-10, cis-12-CLA were found to activate FFA1 in vitro at concentrations sufficient to also account for FFA1 activation in vivo. Each CLA isomer markedly increased glucose-stimulated insulin secretion in insulin-producing INS-1E cells that endogenously express FFA1 and in primary pancreatic β-cells of wild type but not FFA1−/− knock-out mice. Our findings establish a clear mechanistic link between CLAs and insulin production and identify the cell surface receptor FFA1 as a molecular target for CLAs, explaining their acute stimulatory effects on insulin secretion in vivo. CLAs are also revealed as insulinotropic components in widely used nutraceuticals, a finding with significant implication for development of FFA1 modulators to treat type 2 diabetes. PMID:21339298

  15. Relationship between glucose oxidation and FFA concentration in septic cancer-bearing patients

    Energy Technology Data Exchange (ETDEWEB)

    Sauerwein, H.P.; Pesola, G.R.; Groeger, J.S.; Jeevanandam, M.; Brennan, M.F.

    1988-11-01

    Glucose oxidation is inhibited in severely ill patients. The present investigation was designed to study the relationship between glucose tissue uptake, glucose oxidation, and FFA concentration in septic cancer-bearing patients. The influence of glucose infusion alone (3.9 mg x kg-1 x min-1), followed by a euglycemic clamp with the same glucose load, on oxidation of glucose, plasma FFA concentration, and lipid oxidation were measured in eight septic cancer-bearing patients. During infusion of 3.9 mg glucose x kg-1 x min-1 glucose tissue uptake was 4.6 +/- 0.3 mg x kg-1 x min-1, glucose oxidation 0.5 +/- 0.2 mg x kg-1 x min-1, FFA concentration 377 +/- 52 mumol x L-1, and lipid oxidation 2.0 +/- 0.2 mumol x kg-1 x min-1. During the euglycemic clamp glucose tissue uptake was 4.4 +/- 0.3 mg x kg-1 x min-1, glucose oxidation rose to 1.8 mg x kg-1 x min-1 (.001 less than P less than .01), FFA concentration dropped to 202 +/- 23 mumol x L-1 (P less than .001), and lipid oxidation to 1.2 +/- 0.2 mumol x kg-1 x min-1 (.001 less than P less than .01). Nonprotein respiratory quotient rose from 0.73 +/- 0.02 to 0.85 +/- 0.02 (.001 less than P less than .01); 11% +/- 5% of the total amount of glucose taken up by the tissues was oxidized during infusion of glucose alone and increased to 42% +/- 6% during the euglycemic glucose clamp. It is concluded that in septic cancer-bearing patients glucose oxidation is inhibited during infusion of 3.9 mg glucose x kg-1 x min-1, even when expressed as percentage of glucose tissue uptake. With insulin, glucose tissue uptake was not influenced, but glucose oxidation expressed as percentage of glucose tissue uptake was normalized.

  16. Determination of SFC, FFA, and equivalent reaction time for enzymatically interestified oils using NIRS.

    Science.gov (United States)

    Houmøller, Lars P; Kristensen, Dorthe; Rosager, Helle

    2007-02-15

    The use of near infrared spectroscopy (NIRS) for rapid determination of the degree of interesterification of blends of palm stearin, coconut oil, and rapeseed oil obtained using an immobilized Thermomyces lanuginosa lipase at 70 degrees C was investigated. Interesterification was carried out by applying both fixed bed and batch reactors. Calibrations were developed for quantitative determination of solid fat content (SFC) at 10, 20, 30, 35, and 40 degrees C and free fatty acid (FFA) resulting in root mean square errors of prediction of 1.0, 1.3, 1.4, 1.6, 1.7, and 0.19% (w/w), respectively. The data showed that NIRS could be used to replace the traditional methods for determining FFA and SFC in vegetable oils. It was possible to monitor the activity of the immobilized enzyme for interesterification of margarine oils by predicting the equivalent reaction time in a batch reactor from NIR spectra. Root mean square errors of prediction for two different oil blends interesterified for 300 and 170min were 21 and 12min, respectively.

  17. Density of states techniques for lattice field theories using the functional fit approach (FFA)

    CERN Document Server

    Gattringer, Christof; Lehmann, Alexander; Törek, Pascal

    2015-01-01

    We discuss a variant of density of states (DoS) techniques for lattice field theories, the so-called "functional fit approach" (FFA). The DoS FFA is based on a density of states rho(x) which is parameterized on small intervals of the argument x of rho(x). On these intervals restricted Monte Carlo simulations with an additional Boltzmann factor exp(lambda x) allow to determine rho(x) very precisely by obtaining its parameters from fitting the Monte Carlo data to a known function of lambda. We describe the method in detail and show its applicability in four different systems, three of which have a complex action problem: The SU(3) spin model with a chemical potential, U(1) lattice gauge theory, the Z(3) spin model with chemical potential, and 2-dimensional U(1) lattice gauge theory with a topological term. In all cases we compare to reference calculations, which partly were done in a dual formulation where the complex action problem is absent. In all four cases we find a very encouraging performance of the DoS ...

  18. A Novel RSSI Prediction Using Imperialist Competition Algorithm (ICA), Radial Basis Function (RBF) and Firefly Algorithm (FFA) in Wireless Networks

    Science.gov (United States)

    Goudarzi, Shidrokh; Haslina Hassan, Wan; Abdalla Hashim, Aisha-Hassan; Soleymani, Seyed Ahmad; Anisi, Mohammad Hossein; Zakaria, Omar M.

    2016-01-01

    This study aims to design a vertical handover prediction method to minimize unnecessary handovers for a mobile node (MN) during the vertical handover process. This relies on a novel method for the prediction of a received signal strength indicator (RSSI) referred to as IRBF-FFA, which is designed by utilizing the imperialist competition algorithm (ICA) to train the radial basis function (RBF), and by hybridizing with the firefly algorithm (FFA) to predict the optimal solution. The prediction accuracy of the proposed IRBF–FFA model was validated by comparing it to support vector machines (SVMs) and multilayer perceptron (MLP) models. In order to assess the model’s performance, we measured the coefficient of determination (R2), correlation coefficient (r), root mean square error (RMSE) and mean absolute percentage error (MAPE). The achieved results indicate that the IRBF–FFA model provides more precise predictions compared to different ANNs, namely, support vector machines (SVMs) and multilayer perceptron (MLP). The performance of the proposed model is analyzed through simulated and real-time RSSI measurements. The results also suggest that the IRBF–FFA model can be applied as an efficient technique for the accurate prediction of vertical handover. PMID:27438600

  19. Agreement technologies

    CERN Document Server

    Ossowski, Sascha

    2013-01-01

    More and more transactions, whether in business or related to leisure activities, are mediated automatically by computers and computer networks, and this trend is having a significant impact on the conception and design of new computer applications. The next generation of these applications will be based on software agents to which increasingly complex tasks can be delegated, and which interact with each other in sophisticated ways so as to forge agreements in the interest of their human users. The wide variety of technologies supporting this vision is the subject of this volume. It summarises

  20. The internal anticipation of sensory action effects: when action induces FFA and PPA activity

    Directory of Open Access Journals (Sweden)

    Simone Kühn

    2010-06-01

    Full Text Available Voluntary action – in particular the ability to produce desired effects in the environment – is fundamental to human existence. According to ideomotor theory we can achieve goals in the environment by means of anticipating their outcomes. We aimed at providing neurophysiological evidence for the assumption that performing actions calls for the activation of brain areas associated with the sensory effects usually evoked by the actions. We conducted an fMRI study in which right and left button presses lead to the presentation of face and house pictures. We compared a baseline phase with the same phase after participants experienced the association between button presses and pictures. We found an increase in the parahippocampal place area (PPA for the response that has been associated with house pictures and fusiform face area (FFA for the response that has been coupled with face pictures. This observation constitutes support for ideomotor theory.

  1. The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis.

    Science.gov (United States)

    Fuller, Miles; Priyadarshini, Medha; Gibbons, Sean M; Angueira, Anthony R; Brodsky, Michael; Hayes, M Geoffrey; Kovatcheva-Datchary, Petia; Bäckhed, Fredrik; Gilbert, Jack A; Lowe, William L; Layden, Brian T

    2015-11-15

    The structure of the human gastrointestinal microbiota can change during pregnancy, which may influence gestational metabolism; however, a mechanism of action remains unclear. Here we observed that in wild-type (WT) mice the relative abundance of Actinobacteria and Bacteroidetes increased during pregnancy. Along with these changes, short-chain fatty acids (SCFAs), which are mainly produced through gut microbiota fermentation, significantly changed in both the cecum and peripheral blood throughout gestation in these mice. SCFAs are recognized by G protein-coupled receptors (GPCRs) such as free fatty acid receptor-2 (FFA2), and we have previously demonstrated that the fatty acid receptor-2 gene (Ffar2) expression is higher in pancreatic islets during pregnancy. Using female Ffar2-/- mice, we explored the physiological relevance of signaling through this GPCR and found that Ffar2-deficient female mice developed fasting hyperglycemia and impaired glucose tolerance in the setting of impaired insulin secretion compared with WT mice during, but not before, pregnancy. Insulin tolerance tests were similar in Ffar2-/- and WT mice before and during pregnancy. Next, we examined the role of FFA2 in gestational β-cell mass, observing that Ffar2-/- mice had diminished gestational expansion of β-cells during pregnancy. Interestingly, mouse genotype had no significant impact on the composition of the gut microbiome, but did affect the observed SCFA profiles, suggesting a functional difference in the microbiota. Together, these results suggest a potential link between increased Ffar2 expression in islets and the alteration of circulating SCFA levels, possibly explaining how changes in the gut microbiome contribute to gestational glucose homeostasis.

  2. Concomitant action of structural elements and receptor phosphorylation determines arrestin-3 interaction with the free fatty acid receptor FFA4

    DEFF Research Database (Denmark)

    Butcher, Adrian J; Hudson, Brian D; Shimpukade, Bharat;

    2014-01-01

    In addition to being nutrients, free fatty acids act as signaling molecules by activating a family of G protein-coupled receptors. Among these is FFA4, previously called GPR120, which responds to medium and long chain fatty acids, including health-promoting ω-3 fatty acids, which have been implic...

  3. Age-dependent atypicalities in body- and face-sensitive activation of the EBA and FFA in individuals with ASD.

    Science.gov (United States)

    Okamoto, Yuko; Kosaka, Hirotaka; Kitada, Ryo; Seki, Ayumi; Tanabe, Hiroki C; Hayashi, Masamichi J; Kochiyama, Takanori; Saito, Daisuke N; Yanaka, Hisakazu T; Munesue, Toshio; Ishitobi, Makoto; Omori, Masao; Wada, Yuji; Okazawa, Hidehiko; Koeda, Tatsuya; Sadato, Norihiro

    2017-06-01

    Individuals with autism spectrum disorder (ASD) have difficuly in recognizing bodies and faces, which are more pronounced in children than adults. If such difficulties originate from dysfunction of the extrastriate body area (EBA) and the fusiform face area (FFA), activation in these regions might be more atypical in children than in adults. We preformed functional magnetic resonance imaging while children and adults with ASD and age-matched typically developed (TD) individuals observed face, body, car, and scene. To examine various aspects, we performed individual region of interest (ROI) analysis, as well as conventional random effect group analysis. At individual ROI analysis, we examined the ratio of participants showing a category-sensitive response, the size of regions, location and activation patterns among the four object categories. Adults with ASD showed no atypicalities in activation of the EBA and FFA, whereas children with ASD showed atypical activation in these regions. Specifically, a smaller percentage of children with ASD showed face-sensitive activation of the FFA than TD children. Moreover, the size of the EBA was smaller in children with ASD than in TD children. Our results revealed atypicalities in both the FFA and EBA in children with ASD but not in adults with ASD. Copyright © 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.

  4. Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes

    DEFF Research Database (Denmark)

    Christiansen, Elisabeth; Urban, Christian; Merten, Nicole;

    2008-01-01

    A series of 4-phenethynyldihydrocinnamic acid agonists of the free fatty acid receptor 1 (FFA 1) has been discovered and explored. The preferred compound 20 (TUG-424, EC 50 = 32 nM) significantly increased glucose-stimulated insulin secretion at 100 nM and may serve to explore the role of FFA 1 i...

  5. An Examination of Middle School Enrollment in Agricultural Education and Membership in the National FFA Organization in the United States. Summary of Research 73.

    Science.gov (United States)

    Rossetti, Rosemarie; And Others

    The status of middle and junior high school agricultural education and Future Farmers of America (FFA) programs in the United States was the focus of a study. Data were collected through a census of the FFA executive secretaries and a survey of a purposive sample of 27 successful middle or junior high school agricultural education programs in 9…

  6. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties

    DEFF Research Database (Denmark)

    Christiansen, Elisabeth; Urban, Christian; Grundmann, Manuel

    2011-01-01

    The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic ß-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already known. Most of these are derived ...

  7. Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40

    DEFF Research Database (Denmark)

    Schmidt, Johannes; Liebscher, Kathrin; Merten, Nicole

    2011-01-01

    Among dietary components, conjugated linoleic acids (CLAs) have attracted considerable attention as weight loss supplements in the Western world because they reduce fat stores and increase muscle mass. However, a number of adverse effects are also ascribed to the intake of CLAs such as aggravatio...... in widely used nutraceuticals, a finding with significant implication for development of FFA1 modulators to treat type 2 diabetes....

  8. Formulation of SrO-MBCUS Agglomerates for Esterification and Transesterification of High FFA Vegetable Oil

    Directory of Open Access Journals (Sweden)

    Prashant Kumar

    2016-08-01

    Full Text Available Musa Balbisiana Colla Underground Stem (MBCUS catalyst was treated thermally mixing with 5:1 w/w of Strontium Oxide (SrO and the dynamic sites were reformed. The MBCUS-SrO showed sharper crystalline phases as evidence from XRD and TEM analysis. The composition and morphology were characterized from BET, SEM, EDX thermo-gravimetric analysis (TGA and XRF analysis. The optimization process for biodiesel production from Jatropha curcas L oil (JCO having high percentage of free fatty acids was carried out using orthogonal arrays adopting the Taguchi method. The linear equation was obtained from the analysis and subsequent biodiesel production (96% FAME was taken away from the JCO under optimal reaction conditions. The biodiesel so prepared had identical characteristics to that with MBCUS alone, but at a lower temperature (200˚C and internal vapour pressure. Metal leaching was much lower while reusability of the catalyst was enhanced. It was also confirmed that the particle size has little impact upon the conversion efficacy, but the basic active sites are more important. Copyright © 2016 BCREC GROUP. All rights reserved Received: 19th August 2015; Revised: 8th December 2015; Accepted: 1st January 2016 How to Cite: Kumar, P., Sarma, A.K., Bansal, A., Jha, M.K. (2016. Formulation of SrO-MBCUS Agglomerates for Esterification and Transesterification of High FFA Vegetable Oil. Bulletin of Chemical Reaction Engineering & Catalysis, 11 (2: 140-150 (doi:10.9767/bcrec.11.2.540.140-150 Permalink/DOI: http://dx.doi.org/10.9767/bcrec.11.2.540.140-150

  9. Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order with ROTC 1, Revision No. 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    Many Federal Facility Agreement and Consent Order (FFACO) Use Restrictions (URs) have been established at various corrective action sites (CASs) as part of FFACO corrective actions (FFACO, 1996; as amended January 2007). Since the signing of the FFACO in 1996, practices and procedures relating to the implementation of risk-based corrective action (RBCA) have evolved. This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). Based on this evaluation, the URs were sorted into the following categories: 1. Where sufficient information exists to determine that the current UR is consistent with the RCBA criteria 2. Where sufficient information exists to determine that the current UR may be removed or downgraded based on RCBA criteria. 3. Where sufficient information does not exist to evaluate the current UR against the RCBA criteria. After reviewing all the existing FFACO URs, the 49 URs addressed in this document have sufficient information to determine that these current URs may be removed or downgraded based on RCBA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RCBA criteria.

  10. Application of Tin(II Chloride Catalyst for High FFA Jatropha Oil Esterification in Continuous Reactive Distillation Column

    Directory of Open Access Journals (Sweden)

    Ratna Dewi Kusumaningtyas

    2016-03-01

    Full Text Available The application of heterogeneous solid acid catalysts in biodiesel production has become popular and gained significant attention over the last few years. It is since these types of catalysts hold the benefits in terms of easy separation from the product, reusability of the catalyst, high selectivity of the reaction. They are also considered sustainable and powerful particularly in organic synthesis. This work studied the use of tin(II chloride as solid Lewis acid catalyst to promote the esterification reaction of high Free Fatty Acid (FFA jatropha oil in continuous reactive distillation column. To obtain the optimum condition, the influences of reaction time, molar ratio of the reactant, and catalyst were investigated. It was revealed that the optimum condition was achieved at the molar ratio of methanol to FFA at 1:60, catalyst concentration of 5%, and reaction temperature of 60°C with the reaction conversion of 90%. This result was significantly superior to the identical reaction performed using batch reactor. The esterification of high FFA jatropha oil using reactive distillation in the presence of tin(II chloride provided higher conversion than that of Amberlyst-15 heterogeneous catalyst and was comparable to that of homogenous sulfuric acid catalyst, which showed 30 and 94.71% conversion, respectively. The esterification reaction of high FFA jatropha oil was subsequently followed by transesterification reaction for the completion of the biodiesel production. Transesterification was carried out at 60 °C, molar ratio of methanol to oil of 1:6, NaOH catalyst of 1%, and reaction time of one hour. The jatropha biodiesel product resulted from this two steps process could satisfy the ASTM and Indonesian biodiesel standard in terms of ester content (97.79 %, density, and viscosity. Copyright © 2016 BCREC GROUP. All rights reserved Received: 10th November 2015; Revised: 4th February 2016; Accepted: 4th February 2016 How to Cite: Kusumaningtyas

  11. Linoleic Acid Activates GPR40/FFA1 and Phospholipase C to Increase [Ca2+]i Release and Insulin Secretion in Islet Beta-Cells

    Institute of Scientific and Technical Information of China (English)

    Yi-jun Zhou; Yu-ling Song; Hui Zhou; Yan Li

    2012-01-01

    To elucidate GPR40/FFA 1 and its downstream signaling pathways in regulating insulin secretion.Methods GPR40/FFA 1 expression was detected by immunofluorescence imaging.We employed linoleic acid (LA),a free fatty acid that has a high affinity to the rat GPR40,and examined its effect on cytosolic free calcium concentration ([Ca2+]i) in primary rat β-cells by Fluo-3 intensity under confocal microscopy recording.Downregulation of GPR40/FFA1 expression by antisense oligonucleotides was performed in pancreatic β-cells,and insulin secretion was assessed by enzyme-linked immunosorbent assay.Results LA acutely stimulated insulin secretion from primary cultured rat pancreatic islets.LA induced significant increase of [Ca2+]i in the presence of 5.6 mmol/L and 11.1 mmol/L glucose,which was reflected by increased Fluo-3 intensity under confocal microscopy recording.LA-stimulated increase in [Ca2+]i and insulin secretion were blocked by inhibition of GPR40/FFA1 expression in β-cells after GPR40/FFA1-specific antisense treatment.In addition,the inhibition of phospholipase C (PLC) activity by U73122,PLC inhibitor,also markedly inhibited the LA-induced [Ca2+]i increase.Conclusion LA activates GPR40/FFA1 and PLC to stimulate Ca2+ release,resulting in an increase in [Ca2+]i and insulin secretion in rat islet β-cells.

  12. Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4*

    Science.gov (United States)

    Butcher, Adrian J.; Hudson, Brian D.; Shimpukade, Bharat; Alvarez-Curto, Elisa; Prihandoko, Rudi; Ulven, Trond; Milligan, Graeme; Tobin, Andrew B.

    2014-01-01

    In addition to being nutrients, free fatty acids act as signaling molecules by activating a family of G protein-coupled receptors. Among these is FFA4, previously called GPR120, which responds to medium and long chain fatty acids, including health-promoting ω-3 fatty acids, which have been implicated in the regulation of metabolic and inflammatory responses. Here we show, using mass spectrometry, mutagenesis, and phosphospecific antibodies, that agonist-regulated phosphorylation of the human FFA4 receptor occurred primarily at five residues (Thr347, Thr349, Ser350, Ser357, and Ser360) in the C-terminal tail. Mutation of these residues reduced both the efficacy and potency of ligand-mediated arrestin-3 recruitment as well as affecting recruitment kinetics. Combined mutagenesis of all five of these residues was insufficient to fully abrogate interaction with arrestin-3, but further mutagenesis of negatively charged residues revealed additional structural components for the interaction with arrestin-3 within the C-terminal tail of the receptor. These elements consist of the acidic residues Glu341, Asp348, and Asp355 located close to the phosphorylation sites. Receptor phosphorylation thus operates in concert with structural elements within the C-terminal tail of FFA4 to allow for the recruitment of arrestin-3. Importantly, these mechanisms of arrestin-3 recruitment operate independently from Gq/11 coupling, thereby offering the possibility that ligands showing stimulus bias could be developed that exploit these differential coupling mechanisms. Furthermore, this provides a strategy for the design of biased receptors to probe physiologically relevant signaling. PMID:24817122

  13. Cerebral lateralization of face-sensitive areas in left-handers: only the FFA does not get it right.

    Science.gov (United States)

    Bukowski, Henryk; Dricot, Laurence; Hanseeuw, Bernard; Rossion, Bruno

    2013-10-01

    Face perception is highly lateralized to the right hemisphere (RH) in humans, as supported originally by observations of face recognition impairment (prosopagnosia) following brain damage. Divided visual field presentations, neuroimaging and event-related potential studies have supported this view. While the latter studies are typically performed in right-handers, the few reported cases of prosopagnosia with unilateral left damage were left-handers, suggesting that handedness may shift or qualify the lateralization of face perception. We tested this hypothesis by recording the whole set of face-sensitive areas in 11 left-handers, using a face-localizer paradigm in functional magnetic resonance imaging (fMRI) (faces, cars, and their phase-scrambled versions). All face-sensitive areas identified (superior temporal sulcus, inferior occipital cortex, anterior infero-temporal cortex, amygdala) were strongly right-lateralized in left-handers, this right lateralization bias being as large as in a population of right-handers (40) tested with the same paradigm (Rossion et al., 2012). The notable exception was the so-called 'Fusiform face area' (FFA), an area that was slightly left lateralized in the population of left-handers. Since the left FFA is localized closely to an area sensitive to word form in the human brain ('Visual Word Form Area' - VWFA), the enhanced left lateralization of the FFA in left-handers may be due to a decreased competition with the representation of words. The implications for the neural basis of face perception, aetiology of brain lateralization in general, and prosopagnosia are also discussed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Gastric mucosal electrical potential difference and blood flow during high FFA/albumin ratios in anaesthetized Göttingen mini-pigs

    DEFF Research Database (Denmark)

    Højgaard, L; Bülow, J B; Madsen, J;

    1988-01-01

    . The gastric blood flow was measured with the radioactive microsphere technique: at basal conditions, during high FFA/albumin ratios, and after normalization of the plasma lipids. The antrum p.d., expressed with gastric lumen negative, decreased during the increased FFA/albumin ratios; from -25 +/- 3 mV to -17......The gastric blood flow and the gastric mucosal potential difference (p.d.) was studied in anaesthetized Göttingen mini-pigs under normal conditions and during increased FFA/albumin ratios. The antrum mucosal p.d. was measured continuously with a newly developed intragastric microelectrode principle...... +/- 4 mV, (P less than 0.05). A further reduction to -12 +/- 3 mV (P less than 0.05) was observed during the normalization of the FFA/albumin ratios. The antrum and corpus mucosal blood flow values were reduced by 37 and 26% during the increased FFA/albumin ratios, and the gastric mucosal blood flow...

  15. Agreement Workflow Tool (AWT)

    Data.gov (United States)

    Social Security Administration — The Agreement Workflow Tool (AWT) is a role-based Intranet application used for processing SSA's Reimbursable Agreements according to SSA's standards. AWT provides...

  16. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

    Science.gov (United States)

    Hudson, Brian D.; Shimpukade, Bharat; Mackenzie, Amanda E.; Butcher, Adrian J.; Pediani, John D.; Christiansen, Elisabeth; Heathcote, Helen; Tobin, Andrew B.; Ulven, Trond

    2013-01-01

    TUG-891 [3-(4-((4-fluoro-4′-methyl-[1,1′-biphenyl]-2-yl)methoxy)phenyl)propanoic acid] was recently described as a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 (FFA4; previously G protein–coupled receptor 120, or GPR120). Herein, we have used TUG-891 to further define the function of FFA4 and used this compound in proof of principle studies to indicate the therapeutic potential of this receptor. TUG-891 displayed similar signaling properties to the LCFA α-linolenic acid at human FFA4 across various assay end points, including stimulation of Ca2+ mobilization, β-arrestin-1 and β-arrestin-2 recruitment, and extracellular signal-regulated kinase phosphorylation. Activation of human FFA4 by TUG-891 also resulted in rapid phosphorylation and internalization of the receptor. While these latter events were associated with desensitization of the FFA4 signaling response, removal of TUG-891 allowed both rapid recycling of FFA4 back to the cell surface and resensitization of the FFA4 Ca2+ signaling response. TUG-891 was also a potent agonist of mouse FFA4, but it showed only limited selectivity over mouse FFA1, complicating its use in vivo in this species. Pharmacologic dissection of responses to TUG-891 in model murine cell systems indicated that activation of FFA4 was able to mimic many potentially beneficial therapeutic properties previously reported for LCFAs, including stimulating glucagon-like peptide-1 secretion from enteroendocrine cells, enhancing glucose uptake in 3T3-L1 adipocytes, and inhibiting release of proinflammatory mediators from RAW264.7 macrophages, which suggests promise for FFA4 as a therapeutic target for type 2 diabetes and obesity. Together, these results demonstrate both potential but also significant challenges that still need to be overcome to therapeutically target FFA4. PMID:23979972

  17. MEDIATION AGREEMENTS LEGAL MODEL

    Directory of Open Access Journals (Sweden)

    Alexander Ponomarev

    2015-07-01

    Full Text Available This article focuses on the legal model of mediation agreements in Russian and international legislation. The authors consider the main provisions of the mediation agreements in civil matters, in particular, is defined by such features of the legal model as the requirements for this type of agreements. In addition, the article discusses the problematic issues of implementation of mediation agreements.

  18. Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle.

    Science.gov (United States)

    Watt, Matthew J; Holmes, Anna G; Steinberg, Gregory R; Mesa, Jose L; Kemp, Bruce E; Febbraio, Mark A

    2004-07-01

    Intramuscular triacylglycerols (IMTG) are proposed to be an important metabolic substrate for contracting muscle, although this remains controversial. To test the hypothesis that reduced plasma free fatty acid (FFA) availability would increase IMTG degradation during exercise, seven active men cycled for 180 min at 60% peak pulmonary O(2) uptake either without (CON) or with (NA) prior ingestion of nicotinic acid to suppress adipose tissue lipolysis. Skeletal muscle and adipose tissue biopsy samples were obtained before and at 90 and 180 min of exercise. NA ingestion decreased (P HSL) activity (CON: 13.9 +/- 2.5, NA: 9.1 +/- 3.0 nmol.min(-1).mg protein(-1)). NA ingestion resulted in decreased whole body fat oxidation and increased carbohydrate oxidation. Despite the decreased whole body fat oxidation, net IMTG degradation was greater in NA compared with CON (net change: CON, 2.3 +/- 0.8; NA, 6.3 +/- 1.2 mmol/kg dry mass). The increased IMTG degradation did not appear to be due to reduced fatty acid esterification, because glycerol 3-phosphate activity was not different between trials and was unaffected by exercise (rest: 0.21 +/- 0.07; 180 min: 0.17 +/- 0.04 nmol.min(-1).mg protein(-1)). HSL activity was not increased from resting rates during exercise in either trial despite elevated plasma epinephrine, decreased plasma insulin, and increased ERK1/2 phosphorylation. AMP-activated protein kinase (AMPK)alpha1 activity was not affected by exercise or NA, whereas AMPKalpha2 activity was increased (P < 0.05) from rest during exercise in NA and was greater (P < 0.05) than in CON at 180 min. These data suggest that plasma FFA availability is an important mediator of net IMTG degradation, and in the absence of plasma FFA, IMTG degradation cannot maintain total fat oxidation. These changes in IMTG degradation appear to disassociate, however, from the activity of the key enzymes responsible for synthesis and degradation of this substrate.

  19. Urban Test Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — RTTC has access to various facilities for use in urban testing applications,including an agreement with the Hazardous Devices School (HDS): a restrictedaccess Urban...

  20. Agreement in Bloomfield.

    Science.gov (United States)

    Langendoen, D. Terence; McDaniel, Dana S.

    A discussion of Leonard Bloomfield's theory on grammatical agreement examines agreement within Bloomfield's overall scheme of syntactic analysis and relates it to current work in syntax. Bloomfield's three types of agreement (concord, government, and cross-reference) are outlined and compared to the contemporary distinction between pro-drop and…

  1. Determination of ether extract digestibility and energy content of specialty lipids with variable FA and FFA content, and the effect of lecithin, for nursery pigs

    Science.gov (United States)

    Various specialty lipids are commercially available and used in nursery pig diets, but may have FA profiles and FFA content that affect their caloric value. In each of 2 experiments, 54 barrows (28-d of age) were fed a common diet for 7-d, allotted to dietary treatments and fed their respective expe...

  2. Leadership and Personal Development Abilities Possessed by High School Seniors Who Are Members in Superior and Non-Superior FFA Chapters, and by Seniors Who Were Never Enrolled in Vocational Agriculture.

    Science.gov (United States)

    Ricketts, S. Clifton; Newcomb, L. H.

    1984-01-01

    A study of the leadership and personal development abilities of four groups of high school seniors, some of whom were members of Future Farmers of America (FFA) and some who were never enrolled in vocational agriculture, found that FFA involvement resulted in more leadership abilities. (JOW)

  3. Pressurized burner test facility

    Energy Technology Data Exchange (ETDEWEB)

    Maloney, D.J.; Norton, T.S.; Hadley, M.A. [Morgantown Energy Technology Center, WV (United States)

    1993-06-01

    The Morgantown Energy Technology Center (METC) is currently fabricating a high-pressure burner test facility. The facility was designed to support the development of gas turbine combustion systems fired on natural gas and coal-derived gaseous fuels containing fuel-bound nitrogen. Upon completion of fabrication and shake-down testing in October 1993, the facility will be available for use by industrial and university partners through Cooperative Research and Development Agreements (CRADAs) or through other cooperative arrangements. This paper describes the burner test facility and associated operating parameter ranges and informs interested parties of the availability of the facility.

  4. In vitro evaluation of nicotinic acetylcholine receptors with 2-[{sup 18}F]F-A85380 in Parkinson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Schmaljohann, Joern [Department of Neurology, University of Bonn (Germany) and Department of Nuclear Medicine, University of Bonn (Germany)]. E-mail: joern.schmaljohann@ukb.uni-bonn.de; Guendisch, Daniela [Department of Pharmaceutical Chemistry, University of Bonn (Germany); Minnerop, Martina [Department of Neurology, University of Bonn (Germany); Bucerius, Jan [Department of Nuclear Medicine, University of Bonn (Germany); Joe, Alexius [Department of Nuclear Medicine, University of Bonn (Germany); Reinhardt, Michael [Department of Nuclear Medicine, University of Bonn (Germany); Guhlke, Stefan [Department of Nuclear Medicine, University of Bonn (Germany); Biersack, Hans-Juergen [Department of Nuclear Medicine, University of Bonn (Germany); Wuellner, Ullrich [Department of Neurology, University of Bonn (Germany)

    2006-04-15

    Nicotinic acetylcholine receptors (nAChR) are involved in many physiological functions and appear to be affected in neurodegenerative diseases like Alzheimer's disease and Parkinson's disease (PD). Here, we describe the in vitro evaluation of nAChRs in PD with 2-[{sup 18}F]F-A85380, a ligand with high affinity to the {beta}2 nAChR subunit. Autoradiography with 2-[{sup 18}F]F-A85380 in untreated rat brain corresponded to the known distribution of {alpha}4{beta}2 nAChRs with high uptake in the thalamus, moderate uptake in the striatum and cortex and low uptake in the cerebellum (47%, 43% and 19% of the thalamus, respectively). The localization of {alpha}4{beta}2 nAChRs in the striatum was investigated in rodents with unilateral lesion of the substantia nigra. 2-[{sup 18}F]F-A85380 binding was significantly reduced in the striatum ipsilateral to the lesion side (to 64% of the contralateral side), indicating that a fraction of {alpha}4{beta}2 nAChRs is located on dopaminergic terminals, whereas another fraction resides on striatal interneurons or cortical afferents. Similarly, in human brain sections of PD patients, 2-[{sup 18}F]F-A85380 uptake was significantly reduced not only in the caudate and putamen but also in the thalamus (approximately 30% of the binding of control brain in all three regions); within the striatum, nAChRs in the putamen were significantly more severely affected as in the caudate. The observed pattern of {alpha}4{beta}2* nAChR loss demonstrates the potential of 2-[{sup 18}F]F-A85380 for further investigations of this positron emission tomography ligand for in vivo studies of {alpha}4{beta}2* nAChRs in PD.

  5. 42 CFR 442.42 - FFP under a retroactive provider agreement following appeal.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false FFP under a retroactive provider agreement... FACILITIES AND INTERMEDIATE CARE FACILITIES FOR THE MENTALLY RETARDED Provider Agreements § 442.42 FFP under.../MR, nonrenewal of a provider agreement, and the State issues a retroactive agreement, FFP...

  6. THE GIFT AGREEMENT

    Directory of Open Access Journals (Sweden)

    Ljupka B.Petrevska

    2014-04-01

    Full Text Available The gift agreement is a bilateral legal contract which is concluded between the donor and the recipiet of a gift, which could be a thing or a property right. It includes no compensation for the donor but requires mutual agreement. Under certain circumstances the gift agreement may be revoked, and it could be done by the conlcuding parts or third parts, all of which cases are stipulated by law more or less precisely from country to country.

  7. Shareholders' agreements in Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2010-01-01

    ’ agreements”) cannot bind the company within the sense of company law under the new state of law, and voting rights agreements, agreements on right of pre-emption etc. will therefore only apply at the level of contract law between the parties to the agreement. This article for European Business Law Review...... (on the basis of unwritten principles of loyalty under contract law) to vote for such a repetition of the central provisions of the owners’ agreement in the articles of association is then analysed....

  8. The Helsinki Agreement

    Science.gov (United States)

    Babel: Journal of the Australian Federation of Modern Language Teachers' Associations, 1977

    1977-01-01

    A reprint of sections of the Helsinki agreement dealing with foreign languages and civilization, and cooperation and exchanges in the field of education. The agreement supports wider knowledge of foreign languages and promotes exchanges, cooperation, lexicography, and specialized programs in adult education. (AMH)

  9. Agreement on African Venture

    Institute of Scientific and Technical Information of China (English)

    LAN XINZHEN

    2010-01-01

    @@ China's biggest aluminum producer Aluminum Corp.China Ltd.(Chalco) signed a binding agreement with the world's second largest mining company,Rio Tinto,on July 29 in Beijing.The agreement will establish a joint venture to develop and operate the Simandou iron ore project in Guinea,Africa.

  10. The Homomorphic Key Agreement

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    There are various challenges that are faced in group communication, so it is necessary to ensure session key. Key agreement is the fundamental cryptographic primitive for establishing a secure communication. It is a process of computing a shared secret contributed by two or more entities such that no single node can predetermine the resulting value. An authenticated key agreement is attained by combining the key agreement protocol with digital signatures. After a brief introduction to existing key agreement in group communication, Making use of the additive-multiplicative homomorphism in the integer ring defined by Sander and Tschudin: A new protocols, called the homomorphism key agreement, was designed, which can be self-contributory, robust, scalable and applicable in group communication.

  11. The Anterior Temporal Face Area Contains Invariant Representations of Face Identity That Can Persist Despite the Loss of Right FFA and OFA.

    Science.gov (United States)

    Yang, Hua; Susilo, Tirta; Duchaine, Bradley

    2016-03-01

    Macaque neurophysiology found image-invariant representations of face identity in a face-selective patch in anterior temporal cortex. A face-selective area in human anterior temporal lobe (fATL) has been reported, but has not been reliably identified, and its function and relationship with posterior face areas is poorly understood. Here, we used fMRI adaptation and neuropsychology to ask whether fATL contains image-invariant representations of face identity, and if so, whether these representations require normal functioning of fusiform face area (FFA) and occipital face area (OFA). We first used a dynamic localizer to demonstrate that 14 of 16 normal subjects exhibit a highly selective right fATL. Next, we found evidence that this area subserves image-invariant representation of identity: Right fATL showed repetition suppression to the same identity across different images, while other areas did not. Finally, to examine fATL's relationship with posterior areas, we used the same procedures with Galen, an acquired prosopagnosic who lost right FFA and OFA. Despite the absence of posterior face areas, Galen's right fATL preserved its face selectivity and showed repetition suppression comparable to that in controls. Our findings suggest that right fATL contains image-invariant face representations that can persist despite the absence of right FFA and OFA, but these representations are not sufficient for normal face recognition.

  12. International Fisheries Agreements

    DEFF Research Database (Denmark)

    Pintassilgo, Pedro; Kronbak, Lone Grønbæk; Lindroos, Marko

    2015-01-01

    This paper surveys the application of game theory to the economic analysis of international fisheries agreements. The relevance of this study comes not only from the existence of a vast literature on the topic but especially from the specific features of these agreements. The emphasis of the survey...... and stability of international fisheries agreements. A key message that emerges from this literature strand is that self-enforcing cooperative management of internationally shared fish stocks is generally difficult to achieve. Hence, the international legal framework and regulations play a decisive role...... is on coalition games, an approach that has become prominent in the fisheries economics literature over the last decade. It is shown that coalition games were first applied to international fisheries agreements in the late 1990s addressing cooperative issues under the framework of characteristic function games...

  13. Trade Agreements PTI

    Data.gov (United States)

    Department of Homeland Security — The objective of the Trade Agreements PTI is to advance CBP’s mission by working with internal and external stakeholders to facilitate legitimate trade and address...

  14. Service level agreements.

    Science.gov (United States)

    Grimwood, A

    1998-02-01

    Service level agreements provide clearer descriptions of the services to be provided and the objectives to be met. In many instances it is the first time that services have been defined allowing their performance to be suitably measured. They should be output based and not too prescriptive on how the services are to be delivered. The emphasis should be on establishing outputs and the arrangements for monitoring achievement. Customer expectations can exceed available resources and arbitration may become necessary if agreement cannot be reached on internal service level agreements. The main requirements of customers for change through service level agreements is usually improved communications on job status that includes notification of any delays and that agreed response times will be met.

  15. Cooperative Fire Protection Agreement

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this Agreement is to provide for cooperation in the prevention, detection and suppression of wildland fires within the protection areas designated in...

  16. On 18 November 2010, CERN signed an agreement with the Facility for Antiproton and Ion Research (FAIR) GmbH, the company that is co-ordinating the construction of the accelerator and experiment facilities for the FAIR project in Germany.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    The agreement, which was signed by CERN's director-general, Rolf Heuer (left) and FAIR's scientific director Boris Sharkov, concerns collaboration in accelerator sciences and technologies and other scientific domains of mutual interest.

  17. Franchise Agreements and Clean Energy: Issues in Illinois

    Science.gov (United States)

    This project evaluates the impact on energy efficiency of municipal franchise agreements that supply electricity or gas service without a direct charge (unbilled energy) for certain municipal government facilities in Illinois.)

  18. Segmentation Similarity and Agreement

    CERN Document Server

    Fournier, Chris

    2012-01-01

    We propose a new segmentation evaluation metric, called segmentation similarity (S), that quantifies the similarity between two segmentations as the proportion of boundaries that are not transformed when comparing them using edit distance, essentially using edit distance as a penalty function and scaling penalties by segmentation size. We propose several adapted inter-annotator agreement coefficients which use S that are suitable for segmentation. We show that S is configurable enough to suit a wide variety of segmentation evaluations, and is an improvement upon the state of the art. We also propose using inter-annotator agreement coefficients to evaluate automatic segmenters in terms of human performance.

  19. The Sicomines Agreement

    DEFF Research Database (Denmark)

    Jansson, Johanna

    ), was to the benefit of the policy preferences of the IMF and the World Bank. This case thus indicates that since China’s own aspirations are changeable, its emergence as an alternative development partner may not bring about any substantive change of direction for the DRC’s international relations. Furthermore......, the investment into the DRC’s mining sector is in itself beneficial for the country, and the renegotiation of the agreement was positive in the sense that the Congolese state guarantee for the mining component was removed. However, the question of whether the Sicomines agreement is a good deal for the DRC...

  20. Cooperative monitoring of regional security agreements

    Energy Technology Data Exchange (ETDEWEB)

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L.

    1995-08-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities: (1) the demilitarization of the Sinai region between Israel and Egypt in the 1970s; (2) the 1991 quadripartite agreement for monitoring nuclear facilities among Brazil, Argentina, The Argentine-Brazilian Agency for Accounting and Control of Nuclear Materials and the International Atomic Energy Agency; and (3) a bilateral Open Skies agreement between Hungary and Romania in 1991. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations.Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  1. FFTF Authorization Agreement

    Energy Technology Data Exchange (ETDEWEB)

    DAUTEL, W.A.

    2000-02-25

    The purpose of the Authorization Agreement is to serve as a mechanism whereby the U.S. Department of Energy, Richland Operations Office (RL) and Fluor Hanford (FH) jointly clarify and agree to key conditions for conducting work safely and efficiently.

  2. A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death.

    Science.gov (United States)

    Baldwin, Aaron C; Green, Christopher D; Olson, L Karl; Moxley, Michael A; Corbett, John A

    2012-06-01

    Exposure of insulin-producing cells to elevated levels of the free fatty acid (FFA) palmitate results in the loss of β-cell function and induction of apoptosis. The induction of endoplasmic reticulum (ER) stress is one mechanism proposed to be responsible for the loss of β-cell viability in response to palmitate treatment; however, the pathways responsible for the induction of ER stress by palmitate have yet to be determined. Protein palmitoylation is a major posttranslational modification that regulates protein localization, stability, and activity. Defects in, or dysregulation of, protein palmitoylation could be one mechanism by which palmitate may induce ER stress in β-cells. The purpose of this study was to evaluate the hypothesis that palmitate-induced ER stress and β-cell toxicity are mediated by excess or aberrant protein palmitoylation. In a concentration-dependent fashion, palmitate treatment of RINm5F cells results in a loss of viability. Similar to palmitate, stearate also induces a concentration-related loss of RINm5F cell viability, while the monounsaturated fatty acids, such as palmoleate and oleate, are not toxic to RINm5F cells. 2-Bromopalmitate (2BrP), a classical inhibitor of protein palmitoylation that has been extensively used as an inhibitor of G protein-coupled receptor signaling, attenuates palmitate-induced RINm5F cell death in a concentration-dependent manner. The protective effects of 2BrP are associated with the inhibition of [(3)H]palmitate incorporation into RINm5F cell protein. Furthermore, 2BrP does not inhibit, but appears to enhance, the oxidation of palmitate. The induction of ER stress in response to palmitate treatment and the activation of caspase activity are attenuated by 2BrP. Consistent with protective effects on insulinoma cells, 2BrP also attenuates the inhibitory actions of prolonged palmitate treatment on insulin secretion by isolated rat islets. These studies support a role for aberrant protein palmitoylation as a

  3. 12 CFR 725.21 - Modification of agreements.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Modification of agreements. 725.21 Section 725.21 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS NATIONAL CREDIT UNION ADMINISTRATION CENTRAL LIQUIDITY FACILITY § 725.21 Modification of agreements....

  4. Facilities & Leadership

    Data.gov (United States)

    Department of Veterans Affairs — The facilities web service provides VA facility information. The VA facilities locator is a feature that is available across the enterprise, on any webpage, for the...

  5. Biochemistry Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Biochemistry Facility provides expert services and consultation in biochemical enzyme assays and protein purification. The facility currently features 1) Liquid...

  6. [8-hydroxy-dihydroberberine ameliorated insulin resistance induced by high FFA and high glucose in 3T3-L1 adipocytes].

    Science.gov (United States)

    Xu, Li-jun; Lu, Fu-er; Yi, Ping; Wang, Zeng-si; Wei, Shi-chao; Chen, Guang; Dong, Hui; Zou, Xin

    2009-11-01

    The purpose of the study is to investigate the effect of 8-hydroxy-dihydroberberine on insulin resistance induced by high free fatty acid (FFA) and high glucose in 3T3-L1 adipocytes and its possible molecular mechanism. Palmic acid or glucose in combination with insulin was used to induce insulin resistance in 3T3-L1 adipocytes. 8-Hydroxy-dihydroberberine and berberine were added to the cultured medium separately, which were considered as treated group and positive control group. The rate of glucose uptake was determined by 2-deoxy-[3H]-D-glucose method. The amount of glucose consumption in the medium was measured by glucose oxidase method. Cell growth and proliferation of 3T3-L1 adipocytes were detected with Cell Counting Kit-8 (CCK-8) assay. After incubated with palmic acid for 24 hours or glucose with insulin for 18 hours, the rate of glucose transport in 3T3-L1 adipocytes was inhibited by 67% and 58%, respectively. The amount of glucose consumption in 3T3-L1 adipose cells was decreased by 41% after cells were incubated with palmic acid for 24 h. However, the above changes were reversed by pretreatment with 8-hydroxy-dihydroberberine for 24 and 48 h. Significant difference existed between groups. Insulin resistance in 3T3-L1 adipocytes, which is induced by high FFA and high glucose, could be ameliorated by 8-hydroxy-dihydroberberine.

  7. Synthesis of silica gel from waste glass bottles and its application for the reduction of free fatty acid (FFA) on waste cooking oil

    Science.gov (United States)

    Sudjarwo, Wisnu Arfian A.; Bee, Mei Magdayanti F.

    2017-06-01

    Synthesis of silica gel from waste glass bottles was conducted with aims to characterize the product and to analyze its application forthe reduction of free fatty acid (FFA) on waste cooking oil. Silica source taken from waste glass bottles was synthesized into silica gel by using the sol-gel method. Several types of silica gel were produced with three different weight ratios of waste glass and sodium hydroxide as an extractor. They were: 1:1, 1:2, and 1:3. The results indicated that synthesized silica possessed morphology innano-sizedranging from 85 nm to 459 nm. Adsorption performance was investigated by a batch system atthe temperature between 70°C and 110°C by a range of 10°C in an hour. Analysis of the adsorption characteristic showed that the highest efficiency value of FFA reduction of 91% was obtained by silica gel with ratiosof 1:1 (SG 1) and 1:3 (SG 3). Their performances were also followed by the decline of the refractive index and the density of waste cooking oil.

  8. Predicative Adjective Agreement

    DEFF Research Database (Denmark)

    Vikner, Sten

    2001-01-01

    German is a complicated language. Any speaker of e.g. French or Danish who has ever tried to learn German would agree to this. Coming from languages with only two genders and with no case outside the pronoun system, German, with three genders and with four cases throughout the nominal system, seems...... unjustifiably complicated, as if it had been specially designed to torment poor students. However, there is one area where German agreement morphology could not possibly be simpler, and where German is much easier for non-native speakers than e.g. French or Danish: predicative adjectives. Both gender and number...... distinctions, disappear when adjectives are used predicatively. This paper will try to account for why the Germanic languages that inflect attiributive adjectives but not predicative ones are all SOV-languages (e.g. German, Dutch, Frisian and Yiddish)....

  9. Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice.

    Science.gov (United States)

    Gupta, Rohit A; Motiwala, Meha N; Dumore, Nitin G; Danao, Kishor R; Ganjare, Anjali B

    2015-04-22

    Piperine, a main component of Piper longum Linn. and Piper nigrum Linn., is a plant alkaloid with a long history of medicinal use. Piperine exhibits antidepressant, hepatoprotective, anti-metastatic, anti-thyroid, immunomodulatory, antitumor and anti-inflammatory activities, However its therapeutic potential in amelioration of ulcerative colitis and the underlying mechanism for anti-inflammatory activity remains unknown.The objective of the present investigation was to unravel the therapeutic potential of piperine on amelioration of IBD using acetic acid induced experimental animal model for ulcerative colitis and to determine the role of TLR4 receptor in signalling pathway of inflammatory gene expression in ulcerative colitis. We induced colitis using acetic acid (150µl of 5% once, intrarectally) in mice and estimated disease activity index (DAI), which took into account weight loss, stool consistency, and occult/gross bleeding. Colon length, spleen weights, ulcer area and ulcer index were measured; histological changes were observed by H&E staining. Effect of piperine on various antioxidant parameter of mice colon such as tissue myeloperoxidase (MPO) accumulation, SOD concentrations, reduced GSH and lipid peroxidation were determined. Pro-inflammatory mediators, namely, nitric oxide (NO), tumour necrosis factor-α (TNF-α) were determined by a TNF-α ELISA kit obtained from Thermo fisher scientific India Pvt. Ltd. Effect of piperine on haematological parameters of mice in acetic acid induced IBD was also determined which involves the estimation of FFA using a commercial free fatty acid fluorometric assay kit. Piperine significantly attenuated acetic acid induced DAI score which implies that it suppresses weight loss, diarrhoea, gross bleeding and infiltration of immune cells. Piperine administration also effectively and dose dependently prevented shortening of colon length and enlargement of spleen size. Histological examination indicated that piperine reduces

  10. VHA Data Sharing Agreement Repository

    Data.gov (United States)

    Department of Veterans Affairs — The VHA Data Sharing Agreement Repository serves as a centralized location to collect and report on agreements that share VHA data with entities outside of VA. It...

  11. Fabrication Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Fabrication Facilities are a direct result of years of testing support. Through years of experience, the three fabrication facilities (Fort Hood, Fort Lewis, and...

  12. Agreement with Subjects in Lubukusu

    Science.gov (United States)

    Diercks, Michael J. K.

    2010-01-01

    This dissertation examines three topics in the morphosyntax of Lubukusu (Bantu, Kenya), all of which are concerned with agreement with subjects: locative inversion, complementizer agreement, and alternative agreement effects in subject extraction. Each topic reports novel Lubukusu data which are both typologically interesting and theoretically…

  13. Facility Microgrids

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Z.; Walling, R.; Miller, N.; Du, P.; Nelson, K.

    2005-05-01

    Microgrids are receiving a considerable interest from the power industry, partly because their business and technical structure shows promise as a means of taking full advantage of distributed generation. This report investigates three issues associated with facility microgrids: (1) Multiple-distributed generation facility microgrids' unintentional islanding protection, (2) Facility microgrids' response to bulk grid disturbances, and (3) Facility microgrids' intentional islanding.

  14. 10 CFR 75.6 - Facility and location reporting.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Facility and location reporting. 75.6 Section 75.6 Energy... AGREEMENT General Provisions § 75.6 Facility and location reporting. (a) Except where otherwise specified... that its facility or location is required to report under the Safeguards Agreement shall make its...

  15. Predicting word sense annotation agreement

    DEFF Research Database (Denmark)

    Martinez Alonso, Hector; Johannsen, Anders Trærup; Lopez de Lacalle, Oier

    2015-01-01

    High agreement is a common objective when annotating data for word senses. However, a number of factors make perfect agreement impossible, e.g. the limitations of the sense inventories, the difficulty of the examples or the interpretation preferences of the annotations. Estimating potential...... agreement is thus a relevant task to supplement the evaluation of sense annotations. In this article we propose two methods to predict agreement on word-annotation instances. We experiment with a continuous representation and a three-way discretization of observed agreement. In spite of the difficulty...

  16. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

    DEFF Research Database (Denmark)

    Hudson, Brian D; Shimpukade, Bharat; Mackenzie, Amanda E;

    2013-01-01

    TUG-891 [3-(4-((4-fluoro-4'-methyl-[1,1'-biphenyl]-2-yl)methoxy)phenyl)propanoic acid] was recently described as a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 (FFA4; previously G protein-coupled receptor 120, or GPR120). Herein, we have used TUG-891 to furthe...

  17. Exploring rater agreement: configurations of agreement and disagreement

    Directory of Open Access Journals (Sweden)

    ALEXANDER VON EYE

    2006-03-01

    Full Text Available At the level of manifest categorical variables, a large number of coefficients and models for the examination of rater agreement has been proposed and used for descriptive and explanatory purposes. This article focuses on exploring rater agreement. Configural Frequency Analysis (CFA is proposed as a method of exploration of cross-classifications of raters’ judgements. CFA allows researchers to (1 examine individual cells and sets of cells in agreement tables; (2 examine cells that indicate disagreement; and (3 explore agreement and disagreement among three or more raters. Four CFA base models are discussed. The first is the model of rater agreement that is also used for Cohen’s (1960  (kappa. This model proposes independence of raters’ judgements. Deviations from this model suggest agreement or disagreement beyond chance. The second CFA model is based on a log-linear null model. This model is also used for Brennan and Prediger’s (1981 n. It proposes a uniform distribution of ratings. The third model is that of Tanner and Young (1985. This model proposes equal weights for agreement cases and independence otherwise. The fourth model is the quasi-independence model. This model allows one to blank out agreement cells and thus to focus solely on patterns of disagreement. Examples use data from applicant selection.

  18. Fibroblast Growth Factor 21 (FGF21, Free Fatty Acid (FFA, High Sensitivity C-reactive Protein (hsCRP and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR Among Indonesian Obese Non-Diabetic Males

    Directory of Open Access Journals (Sweden)

    Yani Lina

    2009-12-01

    Full Text Available BACKGROUND: Fibroblast growth factor-21 (FGF21 is known as an important endocrine and paracrine regulator of metabolic homeostasis. Recent studies have shown that FGF21 attenuates lipolysis in human adipocytes, which is suggested as a FGF21's mechanism as anti-hyperlipidemia, anti-hyperglycemia and anti-obesity. The aim of this study was to measure the correlation between FGF21, FFA, hsCRP and HOMA-IR among Indonesian obese non diabetic males. METHODS: The study was observational with cross sectional design. The analysis was done in 137 subjects aged 30-60 years with non diabetic abdominal obesity. We measured the biochemical markers FGF21, FFA, hsCRP, fasting insulin and fasting glucose. We also measured weight, height, waist circumrefence (WC, creatinine, serum glutamin oxaloacetic transaminase (SGOT, and serum glutamic pyruvic transaminase (SGPT, systolic blood pressure (SBP and diastolic blood pressure (DBP. Correlation between markers was measured using Pearson and Spearman's analysis. RESULTS: There were significant positive correlations between FGF21-HOMA-IR (r=0.314, p=0.000; FGF21-WC (r=0.173, p=0.043; FFA=hsCRP r=0.270, p=0.001; and WC-HOMA-IR (r=0.279, p=0.001. There was significant negative correlation between FGF21-FFA (r=-0.038, p=0.657 and FGF21-hsCRP (r=-0.061, p=0.482. CONCLUSIONS: In this study we found that although there was no significant correlation, FGF21 might act as an anti-lipolytic and anti-inflammation agent among Indonesian obese non-diabetic males. Our findings agree with results of previous studies that the positive correlation between FGF21-WC and FGF21-HOMA-IR might occur as a compensatory mechanism or resistance to FGF21 in obesity. KEYWORDS: obesity, FGF21, FFA, hsCRP, HOMA-IR.

  19. FFA 市场与二手船市场的波动溢出效应%Volatility Spillover Effects Betw een Forw ard Freight M arket and Second-hand Ship M arket

    Institute of Scientific and Technical Information of China (English)

    杨芊; 林国龙; 丁一; 温馨

    2015-01-01

    For analysing the relationship between forward freight market and second‐hand ship market in the shipping market ,we using the Johansen co‐integration test and Granger causality test method to test the volatility spillover effect between FFA market and second‐hand ship market .And explore the relationship between forward freight market (FFA) and second‐hand ship market .The empirical anal‐ysis show s that :FFA market has a has a strong guiding role to the secondhand ship ,second‐hand ves‐sel market will be affected by FFA price and the impact of past behavior ,understanding the relation‐ship between these two markets can help shipping companies and government making better decisions .%文中采用Johansen协整检验和Granger因果关系检验,对FFA成交价格与二手船市场成交价格进行了相关建模分析,从而分析航运市场中的远期运费市场和二手船市场之间存在着波动溢出关系。考察了远期运费市场(FFA )与二手船市场的关系。实证分析说明,证实了 FFA市场对二手船市场存在因果关系,具有较强的引导作用,二手船市场会受到FFA价格变化及其过去行为的影响,理解两者之间的相关性有助于船运公司和政府等部门做出更好的决策。

  20. International Grants and Cooperative Agreements

    Science.gov (United States)

    EPA provides grants and enters into cooperative agreements that support protecting human health and the environment while advancing U.S. national interests through international environmental collaboration.

  1. Labor Agreement Information System (LAIRS)

    Data.gov (United States)

    Office of Personnel Management — The Labor Agreement Information Retrieval System (LAIRS) is a database containing historical information on labor-management relations in the Federal Government. It...

  2. Site maps and facilities listings

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    In September 1989, a Memorandum of Agreement among DOE offices regarding the environmental management of DOE facilities was signed by appropriate Assistant Secretaries and Directors. This Memorandum of Agreement established the criteria for EM line responsibility. It stated that EM would be responsible for all DOE facilities, operations, or sites (1) that have been assigned to DOE for environmental restoration and serve or will serve no future production need; (2) that are used for the storage, treatment, or disposal of hazardous, radioactive, and mixed hazardous waste materials that have been properly characterized, packaged, and labelled, but are not used for production; (3) that have been formally transferred to EM by another DOE office for the purpose of environmental restoration and the eventual return to service as a DOE production facility; or (4) that are used exclusively for long-term storage of DOE waste material and are not actively used for production, with the exception of facilities, operations, or sites under the direction of the DOE Office of Civilian Radioactive Waste Management. As part of the implementation of the Memorandum of Agreement, Field Offices within DOE submitted their listings of facilities, systems, operation, and sites for which EM would have line responsibility. It is intended that EM facility listings will be revised on a yearly basis so that managers at all levels will have a valid reference for the planning, programming, budgeting and execution of EM activities.

  3. 7 CFR 1942.20 - Community Facility Guides.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Community Facility Guides. 1942.20 Section 1942.20...) PROGRAM REGULATIONS (CONTINUED) ASSOCIATIONS Community Facility Loans § 1942.20 Community Facility Guides... Public Works and Development Facilities. (14) Guide 14—Legal Services Agreement. (15) Guide...

  4. Notes on Agreement in Itelmen

    Directory of Open Access Journals (Sweden)

    Jonathan David Bobaljik

    2002-01-01

    Full Text Available Agreement in Itelmen is represented by means of both prefixes and suffixes. While the prefixes reference subjects (of both transitive and intransitive verbs, the suffixal agreement morphemes on a given verb may reference the subject, the object, or an oblique argument, or some combination of these. We propose that the proper characterization of the factors that determine which arguments control suffixal agreement involves a division of labour between morphology and a notion of discourse prominence/salience. In essence, we propose that the suffixal agreement morpheme is an object agreement marker, but the features of the subject are reflected in this position when the object lacks the relevant features (for example, we treat third person as the lack of a person feature, or is absent altogether (thus, intransitive verbs agree twice with their subjects. When a verb occurs with an oblique as well as a direct object, discourse salience will determine which of these non-subject arguments will control object agreement. In addition to providing a description of a complex range of facts from Itelmen, the paper sheds light on the nature of “multiple exponence” and the role of “competition” among affixes for a particular position in the verbal agreement system.

  5. Project of law authorizing the approval of the agreement between the government of the French republic and the government of the Russian federation relative to the civil liability by way of nuclear damage owing to the supply of materials from the French republic devoted to nuclear facilities in the Russian federation; Projet de loi autorisant l'approbation de l'accord entre le gouvernement de la republique francaise et le gouvernement de la federation de Russie relatif a la responsabilite civile au titre de dommages nucleaires du fait de fournitures en provenance de la republique francaise destinees a des installations nucleaires en federation de Russie

    Energy Technology Data Exchange (ETDEWEB)

    Raffarin, J.P.; Villepin, D. de

    2002-07-01

    An agreement between France and Russia was signed on June 20, 2000 about the civil liability of Russia because of the supply of French material devoted to Russian nuclear facilities. This agreement was necessary because Russia do not belong to any of the two big international civil liability systems relative to nuclear energy, i.e. the Paris convention from July 29, 1960 (in the OECD framework) and the Vienna convention from May 21, 1963 (in the IAEA framework). This agreement offers a protection to the French nuclear suppliers against any damage claims in the case of a nuclear accident occurring on the Russian federation territory. This project of law aims at approving this agreement. (J.S.)

  6. Material Transfer Agreement (MTA) | FNLCR

    Science.gov (United States)

    Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Labfor research or testing purposes, with no collaborative research by parties involving the materials.

  7. Corporate Integrity Agreement (CIA) documents

    Data.gov (United States)

    U.S. Department of Health & Human Services — OIG negotiates corporate integrity agreements (CIA) with health care providers and other entities as part of the settlement of Federal health care program...

  8. Corporate Integrity Agreement (CIA) documents

    Data.gov (United States)

    U.S. Department of Health & Human Services — OIG negotiates corporate integrity agreements (CIA) with health care providers and other entities as part of the settlement of Federal health care program...

  9. Mass Customizing IT Service Agreements

    OpenAIRE

    Brocke, Henrik Finn; Uebernickel, Falk; Brenner, Walter

    2010-01-01

    IT service providers shall achieve both cost reduction in their IT operations and customer individuality in service agreements. This article suggests adapting the well known principle of mass customization to balance individuality and standardization in service agreements. Dependent on the commitment modularity type, its employment may not only save time and resources at the point of customer involvement but also allow the pre-engineering of repeatable processes of provisioning and IT operati...

  10. Mammography Facilities

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Mammography Facility Database is updated periodically based on information received from the four FDA-approved accreditation bodies: the American College of...

  11. Health Facilities

    Science.gov (United States)

    Health facilities are places that provide health care. They include hospitals, clinics, outpatient care centers, and specialized care centers, such as birthing centers and psychiatric care centers. When you ...

  12. Canyon Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — B Plant, T Plant, U Plant, PUREX, and REDOX (see their links) are the five facilities at Hanford where the original objective was plutonium removal from the uranium...

  13. Rater agreement in lung scintigraphy.

    Science.gov (United States)

    Christiansen, F; Andersson, T; Rydman, H; Qvarner, N; Måre, K

    1996-09-01

    The PIOPED criteria in their original and revised forms are today's standards in the interpretation of ventilation-perfusion scintigraphy. When the PIOPED criteria are used by experienced raters with training in consensus interpretation, the agreement rates have been demonstrated to be excellent. Our purpose was to investigate the rates of agreement between 2 experienced raters from different hospital who had no training in consensus interpretation. The 2 raters investigated a population of 195 patients. This group included 72 patients from a previous study who had an intermediate probability of pulmonary embolism and who had also been examined by pulmonary angiography. The results demonstrated moderate agreement rates with a kappa value of 0.54 (0.45-0.63 in a 95% confidence interval), which is similar to the kappa value of the PIOPED study but significantly lower than the kappa values of agreement rates among consensus-trained raters. There was a low consistency in the intermediate probability category, with a proportional agreement rate of 0.39 between the experienced raters. The moderate agreement rates between raters from different hospitals make it difficult to compare study populations of a certain scintigraphic category in different hospitals. Further investigations are mandatory for accurate diagnosis when the scintigrams are in the category of intermediate probability of pulmonary embolism.

  14. Rater agreement in lung scintigraphy

    Energy Technology Data Exchange (ETDEWEB)

    Christiansen, F. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Andersson, T. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Rydman, H. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Qvarner, N. [Oerebro Medical Center Hospital (Sweden). Dept. of Diagnostic Radiology; Maare, K. [Huddinge Univ. Hospital (Sweden). Dept. of Diagnostic Radiolgy

    1996-09-01

    Purpose: The PIOPED criteria in their original and revised forms are today`s standards in the interpretation of ventilation-perfusion scintigraphy. When the PIOPED criteria are used by experienced raters with training in consensus interpretation, the agreement rates have been demonstrated to be excellent. Our purpose was to investigate the rates of agreement between 2 experienced raters from different hospitals who had no training in consensus interpretation. Material and Methods: The 2 raters investigated a population of 195 patients. This group included 72 patients from a previous study who had an intermediate probability of pulmonary embolism and who had also been examined by pulmonary angiography. Results: The results demonstrated moderate agreement rates with a kappa value of 0.54 (0.45-0.63 in a 95% confidence interval), which is similar to the kappa value of the PIOPED study but significantly lower than the kappa values of agreement rates among consensus-trained raters. There was a low consistency in the intermediate probability category, with a proportional agreement rate of 0.39 between the experienced raters. Conclusion: The moderate agreement rates between raters from different hospitals make it difficult to compare study populations of a certain scintigraphic category in different hospitals. Further investigations are mandatory for accurate diagnosis when the scintigrams are in the category of intermediate probability of pulmonary embolism. (orig.).

  15. 7 CFR 1220.620 - Facilities.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Facilities. 1220.620 Section 1220.620 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.620 Facilities. Each county FSA...

  16. 7 CFR 1280.624 - Facilities.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Facilities. 1280.624 Section 1280.624 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.624 Facilities. Each county FSA office...

  17. Gender agreement and multiple referents.

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  18. Gender agreement and multiple referents

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  19. Framework agreements in public procurement

    DEFF Research Database (Denmark)

    Andrecka, Marta; Telles, Pedro

    2015-01-01

    Interview with Dr. Marta Andrecka, Postdoctoral Fellow at the Department of Law at the University of Aarhus, where she is currently working on a project called "Dealing with legal loopholes and uncertainties within EU public procurement law regarding framework agreements" sponsored by the Carlsberg...... Foundation. Before taking up her present position she carried out her doctoral research in Denmark and Australia and worked at law offices in both Poland and the UK. The topic for today’s talk is framework agreements, a relatively popular way of undertaking public procurement...

  20. Association Between Free Fatty Acid (FFA and Insulin Resistance: The Role of Inflammation (Adiponectin and high sensivity C-reactive Protein/hs-CRP and Stress Oxidative (Superoxide Dismutase/SOD in Obese Non-Diabetic Individual

    Directory of Open Access Journals (Sweden)

    Indriyanti Rafi Sukmawati

    2009-12-01

    Full Text Available BACKGROUND: Obesity is highly related to insulin resistance, therefore, the increased number of obesity is followed by the increased prevalence of type 2 Diabetes Melitus. Obesity is associated with increased of reactive oxygen species (ROS in muscle, liver and endothelial cells. The increase of ROS would lead to insulin resistance (IR and increased pro-inflammatory protein. FFA plays an important role in IR by inhibiting muscle glucose transport and oxidation via effects on serine/threonine phosphorylation of IRS-1. The aim of this study was discover the existence of SOD, hs-CRP and and adiponectin levels towards the occurrence of insulin resistance which was caused by elevated level of FFA and to discover the interaction between SOD, hs-CRP and adiponectin in non diabetic obese adult male. METHODS: This was observational study with cross sectional design. There were 65 obese male non diabetic subjects and 45 non obese male non diabetic subjects who met the criteria. In this study, measurements were done on body mass index (BMI, fasting glucose, insulin, adiponectin, hs-CRP and SOD. Obese was defined as BMI >25 kg/m2, normal weight was defined as BMI 18.5-23 kh/m2 and Insulin Resistance was defined as HOMA-IR >1. RESULTS: This study showed that Hypoadiponectinemia condition, decreased SOD level and high level of hs-CRP is associated with insulin resistance in obese non diabetic subject. Adiponectin and SOD were correlated negatively with insulin resistance in obese non diabetic (Adiponectin, r=-0.455, p<0.001; SOD, r=-0.262, p=0.003, hs-CRP was positively correlated with insulin resistance in obese non diabetic (r=0.592, p<0.001. FFA levels was increased in obese insulin resistance compared with non obese non insulin resistance. The Odds Ratio of Adiponectin, hs-CRP and SOD in this study was analyzed by logistic binary. The OR for SOD 3.6 (p=0.001, hs-CRP 9.1 (p<0.001 and Adiponectin 7.2 (p<0.001. CONCLUSIONS: This study suggested that FFA

  1. Block Transfer Agreement Evaluation Project

    Science.gov (United States)

    Bastedo, Helena

    2010-01-01

    The objective of this project is to evaluate for the British Columbia Council on Admissions and Transfer (BCCAT) the effectiveness of block transfer agreements (BTAs) in the BC Transfer System and recommend steps to be taken to improve their effectiveness. Findings of this study revealed that institutions want to expand block credit transfer;…

  2. Asian Facilities

    Science.gov (United States)

    Nakahata, M.

    2011-04-01

    Asian underground facilities are reviewed. The YangYang underground Laboratory in Korea and the Kamioka observatory in Japan are operational and several astrophysical experiments are running. Indian Neutrino Observatory(INO) and China JinPing Underground Laboratory (CJPL) are under construction and underground experiments are being prepared. Current activities and future prospects at those underground sites are described.

  3. Environmental Management Waste Management Facility Proxy Waste Lot Profile 6.999 for Building K-25 West Wing, East Tennessee Technology Park, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Rigsby V.P.

    2009-02-12

    In 1989, the Oak Ridge Reservation (ORR), which includes the East Tennessee Technology Park (ETTP), was placed on the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) National Priorities List. The Federal Facility Agreement (FFA) (DOE 1992), effective January 1, 1992, now governs environmental restoration activities conducted under CERCLA at the ORR. Following signing of the FFA, U.S. Department of Energy (DOE), U.S. Environmental Protection Agency (EPA), and the state of Tennessee signed the Oak Ridge Accelerated Cleanup Plan Agreement on June 18, 2002. The purpose of this agreement is to define a streamlined decision-making process to facilitate the accelerated implementation of cleanup, resolve ORR milestone issues, and establish future actions necessary to complete the accelerated cleanup plan by the end of fiscal year 2008. While the FFA continues to serve as the overall regulatory framework for remediation, the Accelerated Cleanup Plan Agreement supplements existing requirements to streamline the decision-making process. Decontamination and decommissioning (D&D) activities of Bldg. K-25, the original gaseous diffusion facility, is being conducted by Bechtel Jacobs Company LLC (BJC) on behalf of the DOE. The planned CERCLA action covering disposal of building structure and remaining components from the K-25 building is scheduled as a non-time-critical CERCLA action as part of DOE's continuous risk reduction strategy for ETTP. The K-25 building is proposed for D&D because of its poor physical condition and the expense of surveillance and maintenance activities. The K-25/K-27 D&D Project proposes to dispose of the commingled waste listed below from the K-25 west side building structure and remaining components and process gas equipment and piping at the Environmental Management Waste Management Facility (EMWMF) under waste disposal proxy lot (WPXL) 6.999: (1) Building structure (e.g. concrete floors [excluding basement

  4. Low emissions combustor test facility

    Energy Technology Data Exchange (ETDEWEB)

    Maloney, D.J.; Hadley, M.S.; Norton, T.S.

    1993-12-01

    The Morgantown Energy Technology Center (METC) is in the process of constructing a low emissions combustor test and research (LECTR) facility designed to support the development of low emissions gas turbine combustion systems fired on natural gas and coal derived gaseous fuels containing fuel bound nitrogen. The LECTR facility is a major test station located within METC`s new combustion facility. The heart of this test station is a 60 centimeter (24 inch) diameter, refractory lined pressure vessel made up of a series of flanged modules. The facility design offers the flexibility to test a variety of low emissions combustion concepts at pressures up to 3 MPa (30 atm). Upon completion of fabrication and shake-down testing in January of 1994, the facility will be available for use by industrial and university partners through Cooperative Research and Development Agreements (CRADAs) or through other cooperative arrangements. This paper is intended to describe the LECTR facility and associated operating parameter ranges and to inform interested parties of the facility availability.

  5. Modeling agreement on bounded scales.

    Science.gov (United States)

    Vanbelle, Sophie; Lesaffre, Emmanuel

    2017-01-01

    Agreement is an important concept in medical and behavioral sciences, in particular in clinical decision making where disagreements possibly imply a different patient management. The concordance correlation coefficient is an appropriate measure to quantify agreement between two scorers on a quantitative scale. However, this measure is based on the first two moments, which could poorly summarize the shape of the score distribution on bounded scales. Bounded outcome scores are common in medical and behavioral sciences. Typical examples are scores obtained on visual analog scales and scores derived as the number of positive items on a questionnaire. These kinds of scores often show a non-standard distribution, like a J- or U-shape, questioning the usefulness of the concordance correlation coefficient as agreement measure. The logit-normal distribution has shown to be successful in modeling bounded outcome scores of two types: (1) when the bounded score is a coarsened version of a latent score with a logit-normal distribution on the [0,1] interval and (2) when the bounded score is a proportion with the true probability having a logit-normal distribution. In the present work, a model-based approach, based on a bivariate generalization of the logit-normal distribution, is developed in a Bayesian framework to assess the agreement on bounded scales. This method permits to directly study the impact of predictors on the concordance correlation coefficient and can be simply implemented in standard Bayesian softwares, like JAGS and WinBUGS. The performances of the new method are compared to the classical approach using simulations. Finally, the methodology is used in two different medical domains: cardiology and rheumatology.

  6. 76 FR 20668 - Notice of Agreements Filed

    Science.gov (United States)

    2011-04-13

    ... amendment deletes Hanjin Shipping as a party to the Agreement. Agreement No.: 012105-001. Title: SCM Lines Transportes/CCNI Agreement. Parties: Compania Chilena de Navegacion Interoceanica S.A. and SCM...

  7. 75 FR 66098 - Notice of Agreements Filed

    Science.gov (United States)

    2010-10-27

    .... Agreement No.: 012067-003. Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co...

  8. 77 FR 12304 - Notice of Agreements Filed

    Science.gov (United States)

    2012-02-29

    ... . Agreement No.: 012067-005. Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co...

  9. 77 FR 72349 - Notice of Agreements Filed

    Science.gov (United States)

    2012-12-05

    ... . Agreement No.: 011707-009. Title: Gulf/South America Discussion Agreement. Parties: BBC Chartering... amendment removes BBC Chartering & Logistic GMBH & Co. KG as a party to the agreement. By Order of the...

  10. 78 FR 48163 - Notice of Agreements Filed

    Science.gov (United States)

    2013-08-07

    ..., Oregon as member to the agreement. Agreement No.: 012184-001. Title: Crowley/Maersk Line Panama--U.S. Space Charter Agreement. Parties: Crowley Latin America Services, LLC and A.P. Moller-Maersk A/S....

  11. 77 FR 45610 - Notice of Agreement Filed

    Science.gov (United States)

    2012-08-01

    ... (202) 523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012125-001. Title: Maersk/Evergreen Slot Exchange Agreement. Parties: A.P. Moller-Maersk A/S and Evergreen Line Joint Service Agreement....

  12. 77 FR 32115 - Notice of Agreements Filed

    Science.gov (United States)

    2012-05-31

    ... Agreement Western Mediterranean-U.S. East Coast. Parties: CMA CGM, S.A. and A.P. Moller-Maersk A/S. Filing.... Synopsis: The amendment would add Morocco to the geographic scope of the agreement. Agreement No.:...

  13. Periodical control of combustion facilities in agreement with the decree no. 98-833 from September 16, 1998. Specialist's guidebook; Controle periodique des installations de combustion au titre du decret no. 98-833 du 16 septembre 1998. Guide de l'expert

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This guidebook aims at specifying some of the conditions of application of the French decree no. 98-833 from September 16, 1998 relative to the periodical control of combustion facilities: 1 - introduction (goal, definitions, reference documents); 2 - objective of the periodical control; 3 - calculation of the characteristic efficiency of a boiler (type of boiler, losses with smokes, losses with unburnt solid residues, radiant and convection losses); 4 - measurement and control instrumentation; 5 - facilities devoted to thermal energy distribution; 6 - combustion quality and good operation of boilers; 7 - filling up of the maintenance book; 8 - operation and maintenance; 9 - report. (J.S.)

  14. The General Unenforceability of Collective Agreements under Nigerian Labour Jurisprudence: The Paradox of Agreement without Agreement

    Directory of Open Access Journals (Sweden)

    Vincent Iwunze

    2013-12-01

    Full Text Available This study considers the status of collective agreements under Nigerian labour law, examining the extent of their enforceability under the extant laws. It considers the emerging trends in some more advanced jurisdictions of the world in that regard and comparatively portrays the anachronisms of the Nigerian law on the point. It takes the position that the current legal climate as regards the legal status of collective agreements under Nigerian law is potentially disruptive of industrial peace and harmony and is bound to occasion serious hardship on employees. The work suggests among others a jurisprudential shift in paradigm if the Nigerian labour jurisprudence must meet and be reflective of modern socio-economic realities.

  15. Emission Facilities - Erosion & Sediment Control Facilities

    Data.gov (United States)

    NSGIC Education | GIS Inventory — An Erosion and Sediment Control Facility is a DEP primary facility type related to the Water Pollution Control program. The following sub-facility types related to...

  16. 12 CFR 614.4345 - Guaranty agreements.

    Science.gov (United States)

    2010-01-01

    ...-Sharing Agreements § 614.4345 Guaranty agreements. Guaranty agreements under which a percentage of the risk associated with specific loans is assumed may be entered into by or among System banks and... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Guaranty agreements. 614.4345 Section 614.4345...

  17. 25 CFR 163.71 - Agreement funding.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Agreement funding. 163.71 Section 163.71 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER GENERAL FORESTRY REGULATIONS Cooperative Agreements § 163.71 Agreement funding. In cooperative agreements, the Secretary is authorized to advance...

  18. 7 CFR 947.111 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... Definitions § 947.111 Marketing agreement. Marketing agreement means Marketing Agreement No. 114, as amended. ... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 947.111 Section 947.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  19. 75 FR 6397 - Notice of Agreements Filed

    Science.gov (United States)

    2010-02-09

    ....gov . Agreement No.: 011346-019. Title: Israel Trade Conference Agreement. Parties: A.P. Moller-Maersk A/S; Maersk Line Limited; and Zim Integrated Shipping Services, Ltd. Filing Party: Howard A. Levy...: The amendment adds American President Lines, Ltd. as a party to the agreement. Agreement No.:...

  20. 78 FR 33840 - Notice of Agreements Filed

    Science.gov (United States)

    2013-06-05

    ... (202)-523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012037-005. Title: Maersk Line/CMA CGM...-003. Title: The World Liner Data Agreement. Parties: ANL Container Line Pty Ltd.; A.P. Moller-Maersk A.... Agreement No.: 012209. Title: APL/Maersk Line Slot Charter Agreement. Parties: American President Lines,...

  1. 75 FR 82025 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-29

    ... amendment updates the corporate addresses of APL and Hyundai. Agreement No.: 011928-005. Title: Maersk Line... Line Vessel Sharing Agreement. Parties: Hamburg-Sud and A.P. Moeller-Maersk A/S. Filing Party: Wayne... services under the agreement. Agreement No.: 012057-005. Title: CMA CGM/Maersk Line Space Charter,...

  2. 77 FR 1689 - Notice of Agreements Filed

    Science.gov (United States)

    2012-01-11

    ... Vietnam. Agreement No.: 012151. Title: Maersk Line/MSC WCCA Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and MSC Mediterranean Shipping Company, S.A. Filing Party: Wayne R. Rohde, Esquire; Cozen O... . Agreement No.: 012150. Title: COSCON/POS Space Charter and Sailing Agreement. Parties: COSCO Container...

  3. 77 FR 61751 - Notice of Agreements Filed

    Science.gov (United States)

    2012-10-11

    ... restates the Agreement. Agreement No.: 012184-000. Title: Crowley/Maersk Line Panama-U.S. Space Charter Agreement. Parties: Crowley Latin America Services, LLC and A.P. Moller-Maersk A/S Filing Party: Wayne R... agreement authorizes Crowley to charter space to Maersk Line in the trade from Panama to the U.S....

  4. 7 CFR 1415.17 - Cooperative agreements.

    Science.gov (United States)

    2010-01-01

    ... the “right of enforcement” clause to read as set forth in the GRP cooperative agreement. This right is... 7 Agriculture 10 2010-01-01 2010-01-01 false Cooperative agreements. 1415.17 Section 1415.17... Cooperative agreements. (a) NRCS may enter into cooperative agreements which establish terms and...

  5. 23 CFR 140.606 - Project agreements.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Project agreements. 140.606 Section 140.606 Highways... Reimbursement for Bond Issue Projects § 140.606 Project agreements. Project Agreements, Form PR-2, shall be prepared and executed. Agreement provision 8 on the reverse side of Form PR-2 1 shall apply for bond issue...

  6. Air Quality Facilities

    Data.gov (United States)

    Iowa State University GIS Support and Research FacilityFacilities with operating permits for Title V of the Federal Clean Air Act, as well as facilities required to submit an air emissions inventory, and other facilities...

  7. Theme: Laboratory Facilities Improvement.

    Science.gov (United States)

    Miller, Glen M.; And Others

    1993-01-01

    Includes "Laboratory Facilities Improvement" (Miller); "Remodeling Laboratories for Agriscience Instruction" (Newman, Johnson); "Planning for Change" (Mulcahy); "Laboratory Facilities Improvement for Technology Transfer" (Harper); "Facilities for Agriscience Instruction" (Agnew et al.); "Laboratory Facility Improvement" (Boren, Dwyer); and…

  8. Between voluntary agreement and legislation

    DEFF Research Database (Denmark)

    Gwozdz, Wencke; Hedegaard, Liselotte; Reisch, Lucia

    2009-01-01

    Voluntary agreements and self-imposed standards are broadly applied to restrict the influence food advertising exerts on children’s food choices – yet their effects are unknown. The current project will therefore investigate whether and, if yes, how the Danish Code for Responsible Food Marketing...... Communication towards Children (hereafter: CODE) – with its dependence on a supportive institutional environment and acceptance of as well as dynamics between involved key stakeholders like consumers, political actors and firms – contributes to fighting the obesity pandemic.Thus, we explore within this article...... what information about the process of implementing the CODE as well as about the evolved dynamics between key stakeholders is already available. Here, the recently published report of the PolMark project sheds light on the dynamics between the key stakeholders in relation to the current Danish...

  9. Energy conservation agreement; Avtale enoek

    Energy Technology Data Exchange (ETDEWEB)

    Helgerud, H.E.; Alm, L.K.; Moeller, H.M.; Finden, P.

    1996-12-01

    The report analyses the possibilities and approaches on the use of energy conservation agreements as a means between the authorities and the industry in Norway, and a particular attention is laid on the connection between energy consumption and CO{sub 2} discharges both nationally and internationally. The authorities define energy conservation as an efficient socio-economic use of energy, and the industrial branch within processing defines the same as an energy saving measure giving positive environmental effects. The study is connected to stationary energy use, and which includes CO{sub 2} discharges. The stationary energy consumption is about 52 TWh/year, and the thermal energy use within the branch contributes to an annual CO{sub 2} discharge of about 4.65 million tons, or 13% of the total CO{sub 2} discharge in Norway (values from 1993). 29 refs., 3 figs., 6 tabs.

  10. 利拉鲁肽下调游离脂肪酸作用下βTC3细胞PERK的表达%The Down-regulation Effect of Liraglutide (Lira) on the Expression of Double-stranded RNA-dependent Protein Kinase-like Endoplasmic Reticulum Kinase (PERK) in βTC3 Cells Induced by Free Fatty Acids (FFA)

    Institute of Scientific and Technical Information of China (English)

    彭红艳; 姬秋和; 周洁; 邢影; 高彬; 曹宏伟; 刘涛

    2012-01-01

    Objective: To investigate the expression of PERK in pTC3 cells exposed to different concentrations of FFA and the intervention effect of Lira on the expression of double-stranded RNA-dependent protein kinase-like endoplasmic reticulum kinase (PERK) induced by FFA. Methods: βTC3 cells were treated with different concentrations of FFA (0,0.125,0.25, 0.5 and 1.0 mmol/L). Western Blot analysis was used to determine the expression of PERK in (3TC3 cells after 24 hours. Afterwards, |JTC3 cells were prein-cubated with different concentrations of Lira(0,0,0.5,1 mg/L)for 6 hours, and different concentrations of FFA(0,l, 1,1 mmol/L) were then added and the cells were incubated for another 24 hours. The expression of PERK was detected. Results:1. After the cells were incubated with FFA of different concentrations for 24 hours, compared with the control group, the expression of PERK in pTC3 cells in the group with 1 mmol/L FFA increased (P<0.05). 2.Compared with that in the group with 1 mmol/L FFA, the expression of PERK decreased (P<0.05) in the group with 0.5 mg/L Lira+1 mmol/L FFA and the group with 1 mg/L Lira+1 mmol/L FFA, and there was statistical difference between the two groups (P<0.05). Conclusion: The expression of PERK in βTC3 cells is up-regulated by administration of FFA of certain concentration, while Lira can reverse this response to some extent, partly inhibiting endoplasmic reticulum stress.%目的:探讨游离脂肪酸(FFA)作用下胰岛βTC3细胞双链RNA依赖性蛋白样内质网激酶(PERK)的表达以及利拉鲁肽(Lira)对其表达的干预作用.方法:以βTC3细胞为研究对象,分为对照组和FFA组(0.125,0.25,0.5及1 mmol/L)孵育24h,Westernblot方法检测PERK的表达.然后,分为对照组,FFA组,和FFA+Lira组(0.5 mg/L和1 mg/L),Lira预孵育6h后,1mmol/L FFA 继续孵育24h,Western blot检测PERK的表达.结果:①不同浓度FFA孵育24h后,与对照组相比,1mmol/L FFA组PERK表达增加(P<0.05).②与1 mmo1/L FFA组相比,0

  11. Calcined solids storage facility closure study

    Energy Technology Data Exchange (ETDEWEB)

    Dahlmeir, M.M.; Tuott, L.C.; Spaulding, B.C. [and others

    1998-02-01

    The disposal of radioactive wastes now stored at the Idaho National Engineering and Environmental Laboratory is currently mandated under a {open_quotes}Settlement Agreement{close_quotes} (or {open_quotes}Batt Agreement{close_quotes}) between the Department of Energy and the State of Idaho. Under this agreement, all high-level waste must be treated as necessary to meet the disposal criteria and disposed of or made road ready to ship from the INEEL by 2035. In order to comply with this agreement, all calcined waste produced in the New Waste Calcining Facility and stored in the Calcined Solids Facility must be treated and disposed of by 2035. Several treatment options for the calcined waste have been studied in support of the High-Level Waste Environmental Impact Statement. Two treatment methods studied, referred to as the TRU Waste Separations Options, involve the separation of the high-level waste (calcine) into TRU waste and low-level waste (Class A or Class C). Following treatment, the TRU waste would be sent to the Waste Isolation Pilot Plant (WIPP) for final storage. It has been proposed that the low-level waste be disposed of in the Tank Farm Facility and/or the Calcined Solids Storage Facility following Resource Conservation and Recovery Act closure. In order to use the seven Bin Sets making up the Calcined Solids Storage Facility as a low-level waste landfill, the facility must first be closed to Resource Conservation and Recovery Act (RCRA) standards. This study identifies and discusses two basic methods available to close the Calcined Solids Storage Facility under the RCRA - Risk-Based Clean Closure and Closure to Landfill Standards. In addition to the closure methods, the regulatory requirements and issues associated with turning the Calcined Solids Storage Facility into an NRC low-level waste landfill or filling the bin voids with clean grout are discussed.

  12. 22 CFR 124.1 - Manufacturing license agreements and technical assistance agreements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Manufacturing license agreements and technical... ARMS REGULATIONS AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.1 Manufacturing... manufacturing license agreements, technical assistance agreements, distribution agreements, or...

  13. 77 FR 58140 - Notice of Agreements Filed

    Science.gov (United States)

    2012-09-19

    .... Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co., Ltd.; Industrial...

  14. 77 FR 56209 - Notice of Agreements Filed

    Science.gov (United States)

    2012-09-12

    .... Title: U.S. Supplemental Agreement to HLC Agreement. Parties: BBC Chartering & Logistics GmbH & Co. KG; Beluga Chartering GmbH; Chipolbrok; Clipper Project Ltd.; Hyndai Merchant Marine Co., Ltd.; Industrial...

  15. 75 FR 37805 - Notice of Agreements Filed

    Science.gov (United States)

    2010-06-30

    ....gov . Agreement No.: 012032-005. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk...

  16. 78 FR 57390 - Notice of Agreements Filed

    Science.gov (United States)

    2013-09-18

    ...; Washington, DC 20006-4007. Synopsis: The amendment deletes A.P. Moller Maersk A/S trading under the name of Maersk Line as a party to the agreement. Agreement No.: 201157-003. Title: USMX-ILA Master...

  17. 76 FR 12962 - Notice of Agreements Filed

    Science.gov (United States)

    2011-03-09

    ... trade. Agreement No.: 012032-007. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk...

  18. 76 FR 72408 - Notice of Agreements Filed

    Science.gov (United States)

    2011-11-23

    ....S. East coast. Agreement No.: 012146. Title: HLAG/HSDG USWC-Mediterranean Vessel Sharing Agreement..., Morocco, Panama, Colombia, the Dominican Republic, Canada, and Mexico. By Order of the Federal...

  19. TRIPs Agreement, Important Multilateral WTO Treaty

    Directory of Open Access Journals (Sweden)

    Oana-Maria Florescu

    2006-08-01

    Full Text Available This article aims at presenting the content and the frame of the TRIPs. Agreement. It starts by introducing the reader to the terms that defined the world economical climate by the time of the Agreement negociation. Also, it explains the need of having an Agreement on intellectual property rights with impact on the business world. Moreover, the article reviews the main provisions of the Agreement and the most important intellectual property rights.

  20. 7 CFR 900.109 - Mediation agreement.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Mediation agreement. 900.109 Section 900.109 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Mediation agreement. An agreement arrived at by mediation shall not become effective until approved by...

  1. 77 FR 58592 - Modified Norway Post Agreement

    Science.gov (United States)

    2012-09-21

    ... Modified Norway Post Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recently-filed Postal Service request to include a modified Norway Post Agreement... existing bilateral agreement for inbound competitive services with Posten Norge AS (Modified Norway...

  2. 7 CFR 966.111 - Marketing Agreement.

    Science.gov (United States)

    2010-01-01

    ... and Regulations Definitions § 966.111 Marketing Agreement. Marketing Agreement means Marketing... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing Agreement. 966.111 Section 966.111 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  3. 7 CFR 946.101 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... WASHINGTON Rules and Regulations Definitions § 946.101 Marketing agreement. Marketing agreement means... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 946.101 Section 946.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  4. 7 CFR 917.101 - Marketing agreement.

    Science.gov (United States)

    2010-01-01

    ... CALIFORNIA Rules and Regulations Definitions § 917.101 Marketing agreement. Marketing agreement means... 7 Agriculture 8 2010-01-01 2010-01-01 false Marketing agreement. 917.101 Section 917.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  5. 77 FR 38288 - Notice of Agreement Filed

    Science.gov (United States)

    2012-06-27

    ... . Agreement No.: 012177. Title: MSC/Maersk Line U.S.-Panama Space Charter Agreement. Parties: Mediterranean Shipping Company S.A. and A.P. Moller-Maersk A/S, trading under the name Maersk Line. Filing Party: Wayne R... agreement authorizes MSC to charter space to Maersk Line in the trade between ports in Panama and ports...

  6. 75 FR 3466 - Notice of Agreement Filed

    Science.gov (United States)

    2010-01-21

    ... . Agreement No.: 012048-001. Title: The Container Trades Statistics Agreement. Parties: A.P. Moeller-Maersk A/S; China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Ltd.; CMA CGM S.A.; Compania Sudamericana de Vapores S.A.; Evergreen Line Joint Service Agreement; Hamburg Sud KG;...

  7. 76 FR 22104 - Notice of Agreements Filed

    Science.gov (United States)

    2011-04-20

    .... Title: Hamburg Sud/Maersk Line Vessel Sharing Agreement. Parties: Hamburg-Sud and A.P. Moeller-Maersk A... 20006. Synopsis: The amendment would revise the amount of capacity provided by Maersk Line and revise... Agreement. Parties: A.P. Moller-Maersk A/S and Evergreen Line Joint Service Agreement. Filing Parties:...

  8. 76 FR 66304 - Notice of Agreements Filed

    Science.gov (United States)

    2011-10-26

    ....gov . Agreement No.: 012032-008. Title: CMA CGM/MSC/Maersk Line North and Central China-U.S. Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk A/S... further slot exchange between Maersk Line and MSC with corresponding changes in the Agreement and...

  9. 75 FR 71704 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-24

    ....gov . Agreement No.: 012032-006. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Two-Loop Space Charter, Sailing and Cooperative Working Agreement. Parties: A.P. Moller-Maersk A/S...: The World Liner Data Agreement. Parties: ANL Container Line Pty Ltd.; A.P. Moller-Maersk A/S; CMA...

  10. 76 FR 28778 - Notice of Agreements Filed

    Science.gov (United States)

    2011-05-18

    ... the parties' U.S. East Coast services from the agreement. Agreement No.: 012126. Title: Maersk Line...: The agreement authorizes Maersk Line to charter space to Dole in the trades between the U.S. Gulf...-Maersk A/S; CMA CGM S.A.; Hamburg-Sud; and Hapag-Lloyd AG. Filing Party: Wayne R. Rohde, Esq.; Cozen...

  11. 76 FR 44914 - Notice of Agreement Filed

    Science.gov (United States)

    2011-07-27

    ... at (202)-523-5793 or tradeanalysis@fmc.gov . Agreement No.: 012134. Title: Maersk Line/MSC Panama Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and Mediterranean Shipping Company S.A. Filing.... Synopsis: The agreement authorizes MSC to charter space to Maersk Line in the trade from Panama to...

  12. 78 FR 55697 - Notice of Agreements Filed

    Science.gov (United States)

    2013-09-11

    ...; Hyundai Merchant Marine (America), Inc.; ``K'' Line America; Maersk Agency USA, Inc.; Mediterranean... Amendment removes Maersk as a party to the Agreement. Agreement No.: 012223. Title: Assessment Agreement of Carrier Members of United States Maritime Alliance, Ltd. Parties: APL, Ltd.; Atlantic Container...

  13. 78 FR 21364 - Notice of Agreements Filed

    Science.gov (United States)

    2013-04-10

    ....gov . Agreement No.: 012057-009. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Asia to USEC and PNW-Suez/PNW & Panama Loops. Parties: A.P. Moller-Maersk A/S and CMA.... Parties: Evergreen Line Joint Service Agreement; Hanjin Shipping Co., Ltd; Nippon Yusen Kaisha; and...

  14. 47 CFR 27.602 - Lease agreements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Lease agreements. 27.602 Section 27.602... Lease agreements. Guard Band licensees may enter into spectrum leasing arrangements under part 1... following conditions: (a) The spectrum lease agreement between the licensee and the spectrum lessee...

  15. International Agreement Will Advance Radio Astronomy

    Science.gov (United States)

    2007-12-01

    scheduled to be complete, with all 10 VLBA antennas upgraded, in August of 2008. The upgrade will make the VLBA's receiving system for 22 GHz 30 percent more sensitive. This will enhance the VLBA's capability to advance a key area of science using rotating disks of water molecules at the cores of distant galaxies to make precise measurements of the distances to those galaxies. This technique, first used in the late 1990s, can measure large cosmic distances directly, without relying on various assumptions required for more indirect techniques. The improved precision is important to resolving a number of frontier astrophysical problems, including the nature of the mysterious "dark energy" that appears to be accelerating the expansion of the Universe. This research project involves scientists from both MPIfR and NRAO, and, in addition to the VLBA, the Effelsberg telescope, the GBT and the VLA. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc. The Max Planck Institute for Radio Astronomy is one of about 80 research institutes of the Max Planck Society for the Promotion of Research in Germany.

  16. The effect of therapeutic life style on serum FFA and constitution index in patients with coronary heart disease complicated metabolic syndrome%治疗性生活方式对合并代谢综合征的冠心病患者血清游离脂肪酸及体质指标的影响∗

    Institute of Scientific and Technical Information of China (English)

    刘小永; 张戈; 杨瑞丰; 林志; 杨瑞

    2015-01-01

    Objective To investigate the level of serum free fatty acid (FFA )after improving the life style in patients with coronary heart disease complicated metabolic syndrome and the effect of therapeutic life style on traditional risk factors of coronary artery disease.Methods A total of 395 patients with coronary heart disease complicated metabolic syndrome were recruited.Pa-tients were divided into intervention group (group A,conventional drug therapy+ intensive life style intervention,n=97)and non-intervention group (group B,conventional drug therapy,n=38)according to the scores of life style.Serum free fatty acid (FFA) was determined by ELASA.The scores of life style was obtained by"life style questionnaire".Results (1)The serum FFA of pa-tients with coronary heart disease complicated metabolic syndrome were positively related to waist circumference and waist-high-ra-tio.(2)Waist circumference,BMI and FFA of group A were significantly lower than those in group B after therapeutic life style in-tervention(P <0.05).(3)Compared with the baseline,the constitution index and FFA in group A were significantly lower after 6-months therapeutic life style intervention(P <0.05).Conclusion Therapeutic life style can reduce the level of FFA and constitution index of the patients with coronary heart disease complicated metabolic syndrome.%目的:探讨合并代谢综合征的冠心病患者生活方式改善后其血清游离脂肪酸(FFA)水平的变化,以及治疗性生活方式对冠心病传统危险因素的影响。方法共筛选135例合并代谢综合征的冠心病患者,分为干预组(A 组,冠心病常规药物治疗+强化生活方式干预,n=97)和非干预组(B 组,冠心病常规药物治疗,n=38)。分别于入选时和随访结束时测定所有入选患者血清 FFA 水平,同时采集所有患者的体质指标进行比较。结果(1)合并代谢综合征的冠心病患者 FFA 水平与腰围和腰高比显著正相关;(2)治疗性生活方式干预后 A

  17. 远期运费协议与粮食期货市场的波动溢出关系%Volatility spillover effect between forward freight agreement and grain futures market

    Institute of Scientific and Technical Information of China (English)

    温馨; 丁一; 林国龙

    2015-01-01

    From the financial point of view, this paper investigates volatility spillovers between forward freight agreement (FFA) and grain futures market. As one of the three major dry bulk cargoes in the world, grain has a mature futures market. FFA and main grain futures transported by Panamax are studied. First, statistical characteristics and co-integration relation of daily return series are analyzed and inspected. A generalized autoregressive conditional heteroskedasticity (GARCH) model is then constructed to ana-lyze correlation and volatility spillover. The results indicate that the grain futures market leads to the changes of FFA market with respect to return and volatility. Thus, this paper demonstrates effectiveness of GARCH-class model to test volatility spillover, providing a theoretical basis for shipping operators.%从金融视角出发,探究远期运费协议和粮食期货市场之间的波动溢出关系。粮食作为世界三大干散货类型之一,具备相当成熟的期货交易市场,故选取远期运费协议(forward freight agreement, FFA)和巴拿马(Panamax)型船主要运载的粮食期货类型进行研究。首先,采取统计特征分析及协整检验对日收益序列进行分析;然后,通过建立广义自回归条件异方差(generalized autoregressive conditional heteroskedasticity, GARCH)模型,分析两个市场间的相关性并对比其波动性。结果表明,粮食期货市场在收益和波动性上均引导FFA市场的变化,论证了GARCH族模型检验波动溢出特征的有效性,并为干散货航运市场参与者和投资者提供理论参考。

  18. Analysis of safeguards information treatment system at the facility level

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Doo; Song, Dae Yong; Kwack, Eun Ho

    2000-12-01

    Safeguards Information Treatment System(SITS) at the facility level is required to implement efficiently the obligations under the Korea-IAEA Safeguards Agreement, bilateral agreements with other countries and domestic law. In this report, the analysis of information, which the SITS treats, and operation environment of SITS including the review of the relationship between safeguards information are described. SITS will be developed to cover the different accounting procedures and methods applied at the various facilities under IAEA safeguards.

  19. ATR National Scientific User Facility 2009 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Todd R. Allen; Mitchell K. Meyer; Frances Marshall; Mary Catherine Thelen; Jeff Benson

    2010-11-01

    This report describes activities of the ATR NSUF from FY-2008 through FY-2009 and includes information on partner facilities, calls for proposals, users week and education programs. The report also contains project information on university research projects that were awarded by ATR NSUF in the fiscal years 2008 & 2009. This research is university-proposed researcher under a user facility agreement. All intellectual property from these experiments belongs to the university per the user agreement.

  20. China-ASEAN investment agreement negotiations

    Institute of Scientific and Technical Information of China (English)

    CHEN Huiping

    2006-01-01

    China and the ASEAN are negotiating to establish a free trade area and an investment agreement is an integral part of it.The ongoing investment agreement negotiations have achieved some basic consensus as to specific contents of the agreement.However,due to the procedural obstacles and substantive controversies,the negotiations have become stagnant.In order to reach a final and successful conclusion of the investment agreement,the procedural obstacles should be' overcome and the substantive controversies be settled since the agreement has economic and political implications for both China and the ASEAN.

  1. Astragalus polysaccharides improve chronic heart failure by promoting myocardial FFA metabolism via AMPK pathway%黄芪多糖对慢性心衰大鼠心肌 AM PK 活性和FFA 代谢的影响

    Institute of Scientific and Technical Information of China (English)

    宋杰; 胡阳黔; 刘坚; 李静

    2015-01-01

    group, model group and APS group (8 rats in each group).The left coronary artery ligation in the rats was conducted to establish myocardial infarc -tion heart failure model.After modeling, the rats in APS group were given APS (3 g· kg-1· d-1) by intragastric adminis-tration for 6 weeks.Left ventricular diastolic diameter (LVD), left ventricular systolic diameter (LVS), left ventricular ejection fraction ( LVEF) and fractional shortening ( FS) were detected by echocardiography .HE staining was used to ob-serve the pathological changes .The concentrations of free fatty acid ( FFA) in the serum and myocardium were observed by the method of acetyl coenzyme A synthetase and acetyl coenzyme A oxidase ( ACS-ACOD ) .The protein levels of total AMP-activated protein kinase (AMPK), phosphorylated AMP-activated protein kinase (p-AMPK), fatty acid translocase (FAT/CD36) and carnitine palmitoyltransferase I (CPT-1) were measured by Western blotting.RESULTS: No signifi-cant difference in each index between sham group and control group was observed .Compared with control group , LVEF and FS in model group was significantly decreased , while LVD and LVS was significantly increased ( P<0.05 ) .The LVEF and FS in APS group were significantly improved compared with model group ( P<0.05 ) , and there was no significant difference between APS group and control group .LVD and LVS in APS group were obviously improved compared with mo-del group (P<0.05), and the difference was significant compared with control group (P<0.05).Compared with control group, focal myocardial necrosis increased , and residual myocardial cells reduced in model group , while those was much better in APS group as compared with model group (P<0.05).The FFA concentrations in the serum and myocardium in model group increased significantly compared with control group ( P<0.05 ) , while those decreased significantly in APS group as compared with model group (P<0.05).The protein levels of p-AMPK, CPT-1, and cell membrane

  2. North Slope, Alaska ESI: FACILITY (Facility Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains data for oil field facilities for the North Slope of Alaska. Vector points in this data set represent oil field facility locations. This data...

  3. ESO and NSF Sign Agreement on ALMA

    Science.gov (United States)

    2003-02-01

    Green Light for World's Most Powerful Radio Observatory On February 25, 2003, the European Southern Observatory (ESO) and the US National Science Foundation (NSF) are signing a historic agreement to construct and operate the world's largest and most powerful radio telescope, operating at millimeter and sub-millimeter wavelength. The Director General of ESO, Dr. Catherine Cesarsky, and the Director of the NSF, Dr. Rita Colwell, act for their respective organizations. Known as the Atacama Large Millimeter Array (ALMA), the future facility will encompass sixty-four interconnected 12-meter antennae at a unique, high-altitude site at Chajnantor in the Atacama region of northern Chile. ALMA is a joint project between Europe and North America. In Europe, ESO is leading on behalf of its ten member countries and Spain. In North America, the NSF also acts for the National Research Council of Canada and executes the project through the National Radio Astronomy Observatory (NRAO) operated by Associated Universities, Inc. (AUI). The conclusion of the ESO-NSF Agreement now gives the final green light for the ALMA project. The total cost of approximately 650 million Euro (or US Dollars) is shared equally between the two partners. Dr. Cesarsky is excited: "This agreement signifies the start of a great project of contemporary astronomy and astrophysics. Representing Europe, and in collaboration with many laboratories and institutes on this continent, we together look forward towards wonderful research projects. With ALMA we may learn how the earliest galaxies in the Universe really looked like, to mention but one of the many eagerly awaited opportunities with this marvellous facility". "With this agreement, we usher in a new age of research in astronomy" says Dr. Colwell. "By working together in this truly global partnership, the international astronomy community will be able to ensure the research capabilities needed to meet the long-term demands of our scientific enterprise, and

  4. Jupiter Laser Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Jupiter Laser Facility is an institutional user facility in the Physical and Life Sciences Directorate at LLNL. The facility is designed to provide a high degree...

  5. Basic Research Firing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

  6. Facility Registry Service (FRS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Facility Registry Service (FRS) provides an integrated source of comprehensive (air, water, and waste) environmental information about facilities across EPA,...

  7. Licensed Healthcare Facilities

    Data.gov (United States)

    California Department of Resources — The Licensed Healthcare Facilities point layer represents the locations of all healthcare facilities licensed by the State of California, Department of Health...

  8. High Throughput Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Argonne?s high throughput facility provides highly automated and parallel approaches to material and materials chemistry development. The facility allows scientists...

  9. Aperture area measurement facility

    Data.gov (United States)

    Federal Laboratory Consortium — NIST has established an absolute aperture area measurement facility for circular and near-circular apertures use in radiometric instruments. The facility consists of...

  10. Environmental Toxicology Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Fully-equipped facilities for environmental toxicology research The Environmental Toxicology Research Facility (ETRF) located in Vicksburg, MS provides over 8,200 ft...

  11. Licensed Healthcare Facilities

    Data.gov (United States)

    California Department of Resources — The Licensed Healthcare Facilities point layer represents the locations of all healthcare facilities licensed by the State of California, Department of Health...

  12. 22 CFR 124.6 - Termination of manufacturing license agreements and technical assistance agreements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Termination of manufacturing license agreements... Termination of manufacturing license agreements and technical assistance agreements. The U.S. party to a manufacturing license or a technical assistance agreement must inform the Directorate of Defense Trade...

  13. Guide to research facilities

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This Guide provides information on facilities at US Department of Energy (DOE) and other government laboratories that focus on research and development of energy efficiency and renewable energy technologies. These laboratories have opened these facilities to outside users within the scientific community to encourage cooperation between the laboratories and the private sector. The Guide features two types of facilities: designated user facilities and other research facilities. Designated user facilities are one-of-a-kind DOE facilities that are staffed by personnel with unparalleled expertise and that contain sophisticated equipment. Other research facilities are facilities at DOE and other government laboratories that provide sophisticated equipment, testing areas, or processes that may not be available at private facilities. Each facility listing includes the name and phone number of someone you can call for more information.

  14. Analyzing rater agreement manifest variable methods

    CERN Document Server

    von Eye, Alexander

    2014-01-01

    Agreement among raters is of great importance in many domains. For example, in medicine, diagnoses are often provided by more than one doctor to make sure the proposed treatment is optimal. In criminal trials, sentencing depends, among other things, on the complete agreement among the jurors. In observational studies, researchers increase reliability by examining discrepant ratings. This book is intended to help researchers statistically examine rater agreement by reviewing four different approaches to the technique.The first approach introduces readers to calculating coefficients that allow one to summarize agreements in a single score. The second approach involves estimating log-linear models that allow one to test specific hypotheses about the structure of a cross-classification of two or more raters'' judgments. The third approach explores cross-classifications or raters'' agreement for indicators of agreement or disagreement, and for indicators of such characteristics as trends. The fourth approach compa...

  15. AN IMPROVED AUTHENTICATED KEY AGREEMENT PROTOCOL

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In 1999, Seo and Sweeney proposed a simple authenticated key agreement protocol that was designed to act as a Diffie-Hellman key agreement protocol with user authentication.Various attacks on this protocol are described and enhanced in the literature. Recently, Ku and Wang proposed an improved authenticated key agreement protocol, where they asserted the protocol could withstand the existing attacks. This paper shows that Ku and Wang's protocol is still vulnerable to the modification attack and presents an improved authenticated key agreement protocol to enhance the security of Ku and Wang's protocol. The protocol has more efficient performance by replacing exponentiation operations with message authentication code operations.

  16. Report made on behalf of the commission of foreign affairs about the project of law, adopted by the senate, authorizing the approval of the agreement between the French government and the preliminary commission of the organization of the nuclear test ban treaty, about the conduct of the activities relative to the international control facilities, including the post-certification activities; Rapport fait au nom de la Commission des Affaires Etrangeres sur le projet de Loi, adopte par le Senat, autorisant l'approbation de l'accord entre le Gouvernement de la Republique francaise et la Commission preparatoire de l'organisation du traite d'interdiction complete des essais nucleaires sur la conduite des activites relatives aux installations de surveillance international, y compris les activites posterieures a la certification (ensemble une annexe)

    Energy Technology Data Exchange (ETDEWEB)

    Cazenave, R

    2003-12-01

    France and the preliminary commission of the comprehensive nuclear test ban treaty organization (CTBTO) concluded on July 13, 2001, an agreement about the conduct of the activities relative to the international surveillance facilities. This agreement aims at organizing the modalities of implementation of the surveillance activities carried out by the technical secretariat of the preliminary committee of CTBTO in the French territory. This document is the report of the French national assembly about the project of law for the approval of this agreement. It presents the difficult implementation of an international test ban system, the French commitment in the comprehensive nuclear test ban treaty (CTBT), and the main dispositions of the agreement of July 13, 2001. (J.S.)

  17. Reliable Facility Location Problem with Facility Protection.

    Science.gov (United States)

    Tang, Luohao; Zhu, Cheng; Lin, Zaili; Shi, Jianmai; Zhang, Weiming

    2016-01-01

    This paper studies a reliable facility location problem with facility protection that aims to hedge against random facility disruptions by both strategically protecting some facilities and using backup facilities for the demands. An Integer Programming model is proposed for this problem, in which the failure probabilities of facilities are site-specific. A solution approach combining Lagrangian Relaxation and local search is proposed and is demonstrated to be both effective and efficient based on computational experiments on random numerical examples with 49, 88, 150 and 263 nodes in the network. A real case study for a 100-city network in Hunan province, China, is presented, based on which the properties of the model are discussed and some managerial insights are analyzed.

  18. Cooperative monitoring of regional security agreements

    Energy Technology Data Exchange (ETDEWEB)

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.L. [Sandia National Labs., Albuquerque, NM (United States). Nonproliferation and Arms Control Analysis Dept.

    1996-11-01

    This paper argues that cooperative monitoring plays a critical role in the implementation of regional security agreements and confidence building measures. A framework for developing cooperative monitoring options is proposed and several possibilities for relating bilateral and regional monitoring systems to international monitoring systems are discussed. Three bilateral or regional agreements are analyzed briefly to illustrate different possibilities. These examples illustrate that the relationship of regional or bilateral arms control or security agreements to international agreements depends on a number of factors: the overlap of provisions between regional and international agreements; the degree of interest in a regional agreement among the international community; efficiency in implementing the agreement; and numerous political considerations. Given the importance of regional security to the international community, regions should be encouraged to develop their own infrastructure for implementing regional arms control and other security agreements. A regional infrastructure need not preclude participation in an international regime. On the contrary, establishing regional institutions for arms control and nonproliferation could result in more proactive participation of regional parties in developing solutions for regional and international problems, thereby strengthening existing and future international regimes. Possible first steps for strengthening regional infrastructures are identified and potential technical requirements are discussed.

  19. 7 CFR 1424.5 - Agreement process.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Agreement process. 1424.5 Section 1424.5 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOENERGY PROGRAM § 1424.5 Agreement process. (a)...

  20. 12 CFR 619.9240 - Participation agreement.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Participation agreement. 619.9240 Section 619.9240 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DEFINITIONS § 619.9240 Participation agreement. A contract under which a lender agrees to sell a portion of a loan to one or...

  1. Your EHR license agreement: critical issues.

    Science.gov (United States)

    Shay, Daniel F

    2014-01-01

    This article discusses several key provisions and concepts in software license agreements for electronic health records. It offers insight into what physician practices can expect to find in their license agreements, as well as practical advice on beneficial provisions. The article examines contractual language relating to term and termination, technical specifications and support, and compliance with governmental programs.

  2. Approximation algorithms for nonbinary agreement forests

    NARCIS (Netherlands)

    Iersel, L.J.J. van; Kelk, S.M.; Lekic, N.; Stougie, L.

    2012-01-01

    Given two rooted phylogenetic trees on the same set of taxa X, the Maximum Agreement Forest problem (MAF) asks to find a forest that is, in a certain sense, common to both trees and has a minimum number of components. The Maximum Acyclic Agreement Forest problem (MAAF) has the additional restriction

  3. 48 CFR 1542.1203 - Processing agreements.

    Science.gov (United States)

    2010-10-01

    ... MANAGEMENT CONTRACT ADMINISTRATION Novation and Change of Name Agreements 1542.1203 Processing agreements. (a... required documentary evidence. (2) Verify the accuracy of the list of contracts through the Contract... to the Director, Policy, Training and Oversight Division, and to each affected contract office....

  4. 76 FR 11473 - Notice of Agreements Filed

    Science.gov (United States)

    2011-03-02

    ...; American President Lines, Ltd.; Maersk Line Limited; and Zim Integrated Shipping Services, Ltd. Filing... American President Lines Ltd. and APL Co Pte. Ltd. Agreement No.: 012036-002. Title: Maersk Line/MSC TP5... revise the amount of space to be chartered. Agreement No.: 012119. Title: Maersk Line/CMA CGM TP5...

  5. 78 FR 78956 - Notice of Agreements Filed

    Science.gov (United States)

    2013-12-27

    ... . Agreement No.: 012032-009. Title: CMA CGM/MSC/Maersk Line North and Central China-US Pacific Coast Three... overall slots allocations. The amendment also adds new language authorizing Maersk Line to charter space to CMA CGM on its TP6 service. Agreement No.: 012238. Title: HLAG/Maersk Line Gulf-Central...

  6. 75 FR 67749 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-03

    ...: APL/Maersk Line Reciprocal Space Charter Agreement. Parties: American President Lines, Ltd.; APL Co....: 011435-014. Title: APL/HLAG Space Charter Agreement. Parties: American President Lines, Ltd.; APL Co. Pte.... Moller-Maersk A/S; CMA CGM S.A.; Hamburg-S d; and Hapag-Lloyd AG. Filing Party: Wayne R. Rohde,...

  7. 78 FR 66713 - Notice of Agreements Filed

    Science.gov (United States)

    2013-11-06

    ....; American President Lines, Ltd.; A.P. Moller-Maersk A/S; CMA CGM, S.A.; Atlantic Container Line; China... Caribbean Services LLC; Hybur Ltd.; King Ocean Services Limited; Seaboard Marine, Ltd.; Seafreight Line, Ltd... would add US Lines Limited as a party to the agreement. Agreement No.: 011284-072. Title: Ocean...

  8. 78 FR 40739 - Notice of Agreements Filed

    Science.gov (United States)

    2013-07-08

    ... . Agreement No.: 012084-002. Title: HLAG/Maersk Line Gulf-South America Slot Charter Agreement. Parties: A.P. Moller-Maersk A/S and Hapag-Lloyd AG. Filing Party: Robert K. Magovern, Esq.; Cozen O'Connor; 1627 I... service string from which Maersk could charter space from Hapag-Lloyd. The parties have...

  9. 78 FR 64940 - Notice of Agreements Filed

    Science.gov (United States)

    2013-10-30

    .... Agreement No.: 012230. Title: P3 Network Vessel Sharing Agreement. Parties: A.P. Moller-Maersk A/S trading under the name Maersk Line; CMA CGM S.A.; and MSC Mediterranean Shipping Company, S.A. Filing Party... Yusen Kaisha and Eukor Car Carrier Inc. ] Filing Party: Robert Shababb, Corporate Counsel, NYK...

  10. 77 FR 18815 - Notice of Agreements Filed

    Science.gov (United States)

    2012-03-28

    ... . Agreement No.: 012037-003. Title: Maersk Line/CMA CGM TA3 Space Charter Agreement. Parties: A.P. Moeller-Maersk A/S and CMA CGM S.A. Filing Party: Wayne R. Rohde, Esq.; Cozen O'Connor; 1627 I Street NW.,...

  11. 77 FR 42310 - Notice of Agreements Filed

    Science.gov (United States)

    2012-07-18

    ... . Agreement No.: 012119-001. Title: Maersk Line/CMA CGM TP5 Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and CMA CGM S.A. Filing Parties: Wayne Rohde, Esq.; Cozen O'Connor; 1627 I Street NW.; Suite... language reflecting the fact that Maersk's TP5 service will be operated in cooperation with another...

  12. 77 FR 59193 - Notice of Agreement Filed

    Science.gov (United States)

    2012-09-26

    ... . Agreement No.: 012159-001. Title: Maersk Line/New World Alliance Slot Exchange Agreement. Parties: A.P. Moller-Maersk A/S trading under the name of Maersk Line; American President Lines, Ltd.; APL Co. Pte, Ltd.; Hyundai Merchant Marine Co., Ltd.; and Mitsui O.S.K. Lines, Ltd. (``MOL''). Filing Party: David F....

  13. 75 FR 69079 - Notice of Agreements Filed

    Science.gov (United States)

    2010-11-10

    ....gov . Agreement No.: 011261-009. Title: ACL/Wallenius Wilhelmsen Lines Agreement. Parties: Atlantic Container Line AB and Wallenius Wilhelmsen Logistics AS (``WWL''). Filing Party: Wayne R. Rohde, Esq.; Cozen...: A.P. Moller-Maersk A/S; CMA CGM S.A.; Compania Chilena de Navegacion Interoceanica S.A.;...

  14. 75 FR 74732 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-01

    ... APL's corporate address. Agreement No.: 012086-001. Title: Maersk Line/Horizon Lines Space Charter Agreement. Parties: A.P. Moller-Maersk A/S and Horizon Lines, LLC. Filing Party: Matthew Thomas, Esq.; Reed...-Maersk A/S; APL Co. Pte Ltd.; Compania Chilena de Navegacion Interoceanica, S.A.; Compania Sud...

  15. 76 FR 7209 - Notice of Agreements Filed

    Science.gov (United States)

    2011-02-09

    ... Lines, Ltd.; APL Co. PTE Ltd.; A.P. Moller-Maersk A/S; and Hapag-Lloyd USA, LLC. Filing Party: Wayne... Line, Ltd. as a party to the agreement. Agreement No.: 012061-002. Title: CMA CGM/Maersk Line Space....: 010982-048. Title: Florida-Bahamas Shipowners and Operators Association. Parties: Bernuth Lines,...

  16. 76 FR 41794 - Notice of Agreements Filed

    Science.gov (United States)

    2011-07-15

    ..., S.A.; Frontier Liner Services, Inc.; Hamburg-S d; Interocean Lines, Inc.; King Ocean Services..., Ltd. (dba Ecuadorian Line); and Trinity Shipping Line. Filing Party: Wayne R. Rohde, Esq.; Cozen O.... Moller-Maersk A/S as a party to the agreement. Agreement No.: 011814-005. Title: HSDG/King Ocean...

  17. 75 FR 78245 - Notice of Agreements Filed

    Science.gov (United States)

    2010-12-15

    ... Services, Inc.; Farrell Lines, Inc.; Hapag-Lloyd USA, LLC; Maersk Line, Inc.; Maersk Line, Limited; and...: Evergreen Line Joint Service Agreement and A.P. Moller- Maersk A/S. Filing Party: Paul M. Keane, Esq...: The agreement authorizes Maersk to charter space from Evergreen Line in the trade from ports in...

  18. 77 FR 20398 - Notice of Agreements Filed

    Science.gov (United States)

    2012-04-04

    ... . Agreement No.: 012057-007. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Asia to USEC and PNW-Suez/PNW & Panama Loops. Parties: A.P. Moller-Maersk A/S and CMA CGM...

  19. 78 FR 25443 - Notice of Agreements Filed

    Science.gov (United States)

    2013-05-01

    .... Agreement No.: 012172-001. Title: Maersk Line/MSC Caribbean Space Charter Agreement. Parties: A.P. Moller-Maersk A/S trading under the name Maersk Line and Mediterranean Shipping Company S.A. Filing Party: Wayne..., Ltd.; Seafreight Line, Ltd.; Tropical Shipping and Construction Company Limited; and Zim...

  20. 76 FR 19096 - Notice of Agreements Filed

    Science.gov (United States)

    2011-04-06

    ....gov . Agreement No.: 011928-006. Title: Maersk Line/HLAG Slot Charter Agreement. Parties: A.P. Moller-Maersk A/S and Hapag-Lloyd AG. Filing Party: Wayne Rohde, Esq.; Cozen O'Connor; 1627 I Street, NW.; Suite...-Lloyd Aktiengesellschaft; Nippon Yusen ] Kaisha; Orient Overseas Container Line Limited; and...

  1. 12 CFR 1291.9 - Agreements.

    Science.gov (United States)

    2010-01-01

    ... with each member receiving an AHP subsidized advance or AHP direct subsidy an agreement or agreements... Bank policies relevant to the member's approved application for AHP subsidy. (2) AHP subsidy pass-through. The member shall pass on the full amount of the AHP subsidy to the project or household,...

  2. 77 FR 33459 - Notice of Agreements Filed

    Science.gov (United States)

    2012-06-06

    ...: The amendment would add Morocco to the geographic scope of the agreement, adjust the amount of space....S. East Coast Slot Charter Agreement. Parties: Hyundai Merchant Marine Co., Ltd., Mistsui O.S.K... and Gulf Coasts to ports in countries bordering the Red Sea and Arabian Gulf. By Order of the...

  3. 40 CFR 2.215 - Confidentiality agreements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Confidentiality agreements. 2.215 Section 2.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PUBLIC INFORMATION Confidentiality of Business Information § 2.215 Confidentiality agreements. (a) No EPA officer, employee...

  4. Agreement Theorems in Dynamic-Epistemic Logic

    NARCIS (Netherlands)

    Degremont, Cedric; Roy, Oliver

    2012-01-01

    This paper introduces Agreement Theorems to dynamic-epistemic logic. We show first that common belief of posteriors is sufficient for agreement in epistemic-plausibility models, under common and well-founded priors. We do not restrict ourselves to the finite case, showing that in countable structure

  5. LEASING CONTRACT IN THE LEASING AGREEMENT

    Directory of Open Access Journals (Sweden)

    Prudnikova A. E.

    2014-12-01

    Full Text Available The presented publication is devoted to the analysis of legal nature of the contract of financial rent (leasing. The article presents the existing approaches to the concept of a leasing agreement, also attempted to determine the place of contract in the lease agreement

  6. Distributivity and Agreement mismatches in Serbian

    NARCIS (Netherlands)

    Bosnic, Ana

    2016-01-01

    This paper presents a truth value judgment study done on two types of numerals in the Serbian numerical system and corresponding verbal agreement mismatch that is characteristic for the numerals in question. Recent work on agreement and distributivity suggests that singular verbal marking promotes d

  7. Agreement Attraction in Comprehension: Representations and Processes

    Science.gov (United States)

    Wagers, Matthew W.; Lau, Ellen F.; Phillips, Colin

    2009-01-01

    Much work has demonstrated so-called attraction errors in the production of subject-verb agreement (e.g., "The key to the cabinets are on the table", [Bock, J. K., & Miller, C. A. (1991). "Broken agreement." "Cognitive Psychology, 23", 45-93]), in which a verb erroneously agrees with an intervening noun. Six self-paced reading experiments examined…

  8. 23 CFR 635.115 - Agreement estimate.

    Science.gov (United States)

    2010-04-01

    ... submitted by the STD for each force account project (see 23 CFR part 635, subpart B) when the plans and... 23 Highways 1 2010-04-01 2010-04-01 false Agreement estimate. 635.115 Section 635.115 Highways... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.115 Agreement estimate. (a) Following the award...

  9. 50 CFR 81.6 - Project Agreement.

    Science.gov (United States)

    2010-10-01

    ... shall certify that the State agency submitting the project is committed to its execution and that is has... Office of Management and Budget Circular No. A-95 (as revised). (d) The Project Agreement will follow... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Project Agreement. 81.6 Section 81.6...

  10. Cooperation Agreement Signed Between CPAFFC and HSF

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>An agreement on cooperation between theCPAFFC and the Hanns Seidel Foundation was signed in Beijing on October 24, 2003. The agreement sets forth the framework of cooperation between the two sides and concrete forms and programmes of cooperation. The two sides will regularly carry out exchanges between parlia-

  11. Determination of Agreement Between Laboratory Instruments.

    Science.gov (United States)

    Gray, Tonya E.; Pratt, Manley C.; Cusick, Patrick K.

    1999-03-01

    The present study was conducted to illustrate the utility of Bland-Altman plots for use by our laboratory staff and other non-statisticians in assessing the agreement between values measured by using two different laboratory instruments. A high degree of agreement reflects acceptable interchangeability of equipment and minimal effect on clinical decision-making. We have summarized literature that suggests that the regression line and correlation coefficient used with regression analysis, although commonly employed, are not appropriate first choices for evaluating agreement. Using the ABL 500 Radiometer and i-STAT Portable Chemistry Analyzer, we evaluated pH, PCO2, and TCO2. Bland-Altman plots were simple to produce, were not mathematics-intensive, and provided an easily interpreted, graphical answer to the question of agreement between instruments. For purposes of clinical decision-making, the ABL and i-STAT machines were found to be in good agreement for the tests evaluated.

  12. Bayesian methods for measures of agreement

    CERN Document Server

    Broemeling, Lyle D

    2009-01-01

    Using WinBUGS to implement Bayesian inferences of estimation and testing hypotheses, Bayesian Methods for Measures of Agreement presents useful methods for the design and analysis of agreement studies. It focuses on agreement among the various players in the diagnostic process.The author employs a Bayesian approach to provide statistical inferences based on various models of intra- and interrater agreement. He presents many examples that illustrate the Bayesian mode of reasoning and explains elements of a Bayesian application, including prior information, experimental information, the likelihood function, posterior distribution, and predictive distribution. The appendices provide the necessary theoretical foundation to understand Bayesian methods as well as introduce the fundamentals of programming and executing the WinBUGS software.Taking a Bayesian approach to inference, this hands-on book explores numerous measures of agreement, including the Kappa coefficient, the G coefficient, and intraclass correlation...

  13. [Innovative medicines and market access agreements].

    Science.gov (United States)

    Toumi, M; Zard, J; Duvillard, R; Jommi, C

    2013-09-01

    Market Access Agreements (MAA) for drugs have emerged in response to the need to control health expenditures, as well as to the uncertainty about the true benefit of a drug. It is possible to group MAA in two types of agreements: financial agreements and outcome-based agreements. MAA is a growing trend and is shifting towards conditional access. However, the willingness to use these contracts and their implementation differ across countries, and some are still resistant to put them in place. The MAA challenges to overcome encompass the complexity of the schemes, the administrative burden and the difficulty of evaluating MAA. It is likely that these agreements might experience further evolution in the future to become a faster pathway for therapeutic innovations, at a fair price.

  14. Concession as a Tool of Infrastructure Facilities Modernization

    Directory of Open Access Journals (Sweden)

    Vitaliy Vladimirovich Peshkov

    2016-12-01

    Full Text Available The development of engineering infrastructure demands carrying out modernization of infrastructure facilities in which the mechanism of public-private partnership plays more and more important role. The need of comprehensive regulation of subjects’ activity in the public-private partnership (PPP field causes Russian legislation development in this sphere. Within promptly enhanced legislation in the field of PPP, development of this direction is promoted by approach, taking into account parties’ economic interests in case of concluding agreements on PPP. We developed algorithm of determining the price of concession agreement of infrastructure facilities on the basis of the principle of the best use of a concession object. This algorithm allows estimating the greatest possible size of a rent from this concession object. Besides, this algorithm allows approaching determination of concession agreement price taking into account the comprehensive expenses accounting by host and allows creating individual terms of agreement irrespective of concession subject type. The developed algorithm finds practical reflection in the practice of concession agreements conclusion between public authorities of the Irkutsk region and business. We have revealed positive dynamics of results of concession agreements application as a tool of modernization of infrastructure facilities, by carrying out analysis of results of municipal property management in heat supply sphere on example of Irkutsk city. We established direct influence of the economic interests synchronization pledged in algorithm of concession agreement price determination, on implementation of investing program actions within the concession agreement.

  15. Service level agreements for cloud computing

    CERN Document Server

    Wieder, Philipp; Theilmann, Wolfgang

    2011-01-01

    Service Level Agreements for Cloud Computing provides a unique combination of business-driven application scenarios and advanced research in the area of service-level agreements for Clouds and service-oriented infrastructures. Current state-of-the-art research findings are presented in this book, as well as business-ready solutions applicable to Cloud infrastructures or ERP (Enterprise Resource Planning) environments. Service Level Agreements for Cloud Computing contributes to the various levels of service-level management from the infrastructure over the software to the business layer, includ

  16. Client/consultant model services agreement

    CERN Document Server

    International Federation of Consulting Engineers

    2006-01-01

    The terms of the Client Consultant Model Services agreement (The White Book) have been prepared by the Fédération Internationale des Ingénieurs-Conseils (FIDIC) and are recommended for general use for the purposes of pre-investment and feasibility studies, designs and administration of construction and project management, where proposals for such services are invited on an international basis. They are equally adaptable for domestic agreements. - See more at: http://fidic.org/books/clientconsultant-model-services-agreement-4th-ed-2006-white-book#sthash.3Uxy5qT3.dpuf

  17. 48 CFR 25.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false World Trade Organization Government Procurement Agreement and Free Trade Agreements. 25.403 Section 25.403 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Trade Agreements 25.403 World Trade...

  18. 75 FR 42445 - Notice of Agreement Filed

    Science.gov (United States)

    2010-07-21

    ... No.: 012105. Title: SCM Lines Transportes/CCNI Agreement. Parties: Compania Chilena de Navegacion Interoceanica S.A. and SCM Lines Transportes Maritimos Sociedade Unipessoal, LDA. Filing Party: John P....

  19. EMI-EDGI Operational Level Agreement

    CERN Document Server

    Di Meglio, Alberto

    2012-01-01

    This document is the Operational Level Agreement signed by EMI and EDGI for the contribution of middleware from EDGI into the EMI distribution and the definition of service levels compatible with the existing EMI SLAs

  20. A Time for Flexible Donor Agreements.

    Science.gov (United States)

    Fischer, Gerald B.

    2003-01-01

    Discusses why volatile markets and new donor expectations make now a good time to rework payout rates and gift agreements to bolster financial and strategic performance. Suggests seven options for action. (EV)

  1. 78 FR 70300 - Notice of Agreements Filed

    Science.gov (United States)

    2013-11-25

    ....: 012230. Title: P3 Network Vessel Sharing Agreement. Parties: A.P. Moller-Maersk A/S trading under the name Maersk Line; CMA CGM S.A.; and MSC Mediterranean Shipping Company, S.A. Filing Party: Wayne...

  2. 76 FR 36537 - Notice of Agreement Filed

    Science.gov (United States)

    2011-06-22

    ... No.: 012130. Title: Maersk Line/HLAG Latin America Slot Exchange Agreement. Parties: A.P. Moller-Maersk A/S and Hapag-Lloyd AG. Filing Parties: Wayne Rohde, esq.; Cozen O'Connor; 1627 I Street,...

  3. 78 FR 63474 - Notice of Agreements Filed

    Science.gov (United States)

    2013-10-24

    ... charter space to Maersk Line in the trade between Guatemala and Honduras, on the one hand, and Miami, FL... China (including Hong Kong), and the Pacific Coast of the U.S. and Canada. Agreement No.: 201221....

  4. New Danish Company Act on Shareholders' Agreements

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2011-01-01

    . The substantial elements in many agreements are clauses on (1) voting for board candidates, (2) voting for dividends of certain proportions, and (3) first refusal rights, respectively, call options for shares in the company. Such clauses are at the very roots of corporate law, dealing with the shareholders’ (1......Section 82 of the Danish Company Act, in force from 1 March 2010, provides that ‘Shareholders’ agreements are neither binding on the company nor on decisions taken by the general assembly’. This has far-reaching consequences for shareholders’ agreements, also for already existing agreements......) dispose of his shares in a different way than what is agreed upon, section 82 will show its ugly face, and contractual law and corporate law must in such cases be regarded as two different worlds. The remedies against this are partly of a contractual nature (penalty, mutual pledge in shares, injunction...

  5. 76 FR 30360 - Notice of Agreements Filed

    Science.gov (United States)

    2011-05-25

    ... Discussion Agreement. Parties: BBC Chartering & Logistic GMBH & Co. KG; Industrial Maritime Carriers (U.S.A... December 14, 1983 Concerning Assessments to Pay ILWU-PMA Employee Benefit Costs, As Amended, Through May 12...

  6. ;Agreement; in the IPCC Confidence measure

    Science.gov (United States)

    Rehg, William; Staley, Kent

    2017-02-01

    The Intergovernmental Panel on Climate Change (IPCC) has, in its most recent Assessment Report (AR5), articulated guidelines for evaluating and communicating uncertainty that include a qualitative scale of confidence. We examine one factor included in that scale: the ;degree of agreement.; Some discussions of the degree of agreement in AR5 suggest that the IPCC is employing a consensus-oriented social epistemology. We consider the application of the degree of agreement factor in practice in AR5. Our findings, though based on a limited examination, suggest that agreement attributions do not so much track the overall consensus among investigators as the degree to which relevant research findings substantively converge in offering support for IPCC claims. We articulate a principle guiding confidence attributions in AR5 that centers not on consensus but on the notion of support. In concluding, we tentatively suggest a pluralist approach to the notion of support.

  7. Interagency Agreement for Wildland Fire Management

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The objectives of this Master Cooperative Wildland Fire Management Agreement are to provide a basis for cooperation among the agencies on all aspects of wildland...

  8. 76 FR 64944 - Notice of Agreements Filed

    Science.gov (United States)

    2011-10-19

    ...: Hamburg-Sud (``HSDG''); Alianca Navegacao e Logistica Ltda. e CIA (``Alianca''); Compania Sud Americana de...-010. Title: Maritime Credit Agreement. Parties: Alianca Navegacao e Logistica Ltda. & Cia.; China...

  9. 7 CFR 3431.18 - Service agreement.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE VETERINARY MEDICINE LOAN REPAYMENT PROGRAM Administration of the Veterinary Medicine Loan Repayment Program § 3431.18 Service agreement. (a) The service...

  10. 32 CFR 644.137 - Maneuver agreements.

    Science.gov (United States)

    2010-07-01

    ... planning and acquires rights to use land and other facilities for Department of the Army exercises. The... camp sites, field hospital sites and supply dumps), and buildings needed for warehouses, ordnance...

  11. The administrative review of concession agreements

    Directory of Open Access Journals (Sweden)

    Fatmira Hajdari

    2014-01-01

    The practice of concessionary agreements in Albania is only in its early steps of development. Furthermore, the legislation that provides for the concession agreements has suffered changes to reflect the international legislation. All of which have led to the case law encountering various issues, which we have only humbly tried to reflect in this paper, while also providing our opinion with regard to addressing them.

  12. 77 FR 16838 - Notice of Agreements Filed

    Science.gov (United States)

    2012-03-22

    ... deletes A.P. Moller-Maersk AS, trading under the name of Maersk Line, as party to the Agreement. Agreement...- Maersk A/S trading under the name of Maersk Line; China Shipping Container Lines Co. Ltd.; CMA CGM A.A...-4007. Synopsis: Adds A.P. Moller-Maersk A/s trading under the name Maersk Line as a party to...

  13. Improved Authenticated Multi-Key Agreement Protocol

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hua; YUAN Zheng; WEN Qiaoyan

    2006-01-01

    Zhou et al give an attack on Harn's modified authenticated multi-key agreement protocol, and give a protocol that can prevent the unknown key-share attack. The paper points out that the protocol is vulnerable to a concatenation attack. This paper proposes an improved authenticated multi-key agreement protocol which shows how to make Harn's protocol more secure by modifying the signature and verification. And this protocol can escape the concatenation attack.

  14. Agricultural Reciprocity under Economic Partnership Agreements

    OpenAIRE

    Christopher Stevens; Jane Kennan

    2006-01-01

    This paper investigates how the formation of Economic Partnership Agreements (EPAs) with the EU might affect the ability of the six Development Cooperation Ireland programme countries in Sub-Saharan Africa to continue to provide protection to their domestic agri-food sectors. Various scenarios are constructed on the assumption that ‘substantially all' trade with the EU must be liberalised if the EPAs are to be compatible with WTO rules on regional trade agreements. The paper concludes that EP...

  15. The North American Free Trade Agreement

    Science.gov (United States)

    1993-02-25

    that would have continued 3 Carlos Salinas de Gortari , Interview, NEW PERSPECTIVES QUARTERLY, Winter 1991, pp. 4-9. 4 Various authors presenting...vast US and Canadian consumer markets and to attract badly needed foreign capital. In this sense, the agreement is the crown jewel in President Salinas ...President Salinas recognizes the importance of the agreement as a means to consolidate gains made to date, thereby providing the "permanence

  16. Technical Safety Requirements for the Gamma Irradiation Facility (GIF)

    CERN Document Server

    Mahn, J A E M J G

    2003-01-01

    This document provides the Technical Safety Requirements (TSR) for the Sandia National Laboratories Gamma Irradiation Facility (GIF). The TSR is a compilation of requirements that define the conditions, the safe boundaries, and the administrative controls necessary to ensure the safe operation of a nuclear facility and to reduce the potential risk to the public and facility workers from uncontrolled releases of radioactive or other hazardous materials. These requirements constitute an agreement between DOE and Sandia National Laboratories management regarding the safe operation of the Gamma Irradiation Facility.

  17. Ouellette Thermal Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Thermal Test Facility is a joint Army/Navy state-of-the-art facility (8,100 ft2) that was designed to:Evaluate and characterize the effect of flame and thermal...

  18. Cold Vacuum Drying Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Located near the K-Basins (see K-Basins link) in Hanford's 100 Area is a facility called the Cold Vacuum Drying Facility (CVDF).Between 2000 and 2004, workers at the...

  19. Dialysis Facility Compare

    Data.gov (United States)

    U.S. Department of Health & Human Services — Dialysis Facility Compare helps you find detailed information about Medicare-certified dialysis facilities. You can compare the services and the quality of care that...

  20. Explosive Components Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The 98,000 square foot Explosive Components Facility (ECF) is a state-of-the-art facility that provides a full-range of chemical, material, and performance analysis...

  1. Materiel Evaluation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — CRREL's Materiel Evaluation Facility (MEF) is a large cold-room facility that can be set up at temperatures ranging from −20°F to 120°F with a temperature change...

  2. Armament Technology Facility (ATF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Armament Technology Facility is a 52,000 square foot, secure and environmentally-safe, integrated small arms and cannon caliber design and evaluation facility....

  3. Integrated Disposal Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Located near the center of the 586-square-mile Hanford Site is the Integrated Disposal Facility, also known as the IDF.This facility is a landfill similar in concept...

  4. Facilities for US Radioastronomy.

    Science.gov (United States)

    Thaddeus, Patrick

    1982-01-01

    Discusses major developments in radioastronomy since 1945. Topics include proposed facilities, very-long-baseline interferometric array, millimeter-wave telescope, submillimeter-wave telescope, and funding for radioastronomy facilities and projects. (JN)

  5. Wastewater Treatment Facilities

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — Individual permits for municipal, industrial, and semi-public wastewater treatment facilities in Iowa for the National Pollutant Discharge Elimination System (NPDES)...

  6. Facility Response Plan (FRP)

    Data.gov (United States)

    U.S. Environmental Protection Agency — A Facility Response Plan (FRP) demonstrates a facility's preparedness to respond to a worst case oil discharge. Under the Clean Water Act, as amended by the Oil...

  7. Financing Professional Sports Facilities

    OpenAIRE

    Baade, Robert A.; Victor A. Matheson

    2011-01-01

    This paper examines public financing of professional sports facilities with a focus on both early and recent developments in taxpayer subsidization of spectator sports. The paper explores both the magnitude and the sources of public funding for professional sports facilities.

  8. FDA Certified Mammography Facilities

    Science.gov (United States)

    ... Program Consumer Information (MQSA) Search for a Certified Facility Share Tweet Linkedin Pin it More sharing options ... Email Print This list of FDA Certified Mammography Facilities is updated weekly. If you click on Search ...

  9. Energetics Conditioning Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Energetics Conditioning Facility is used for long term and short term aging studies of energetic materials. The facility has 10 conditioning chambers of which 2...

  10. Energetics Conditioning Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Energetics Conditioning Facility is used for long term and short term aging studies of energetic materials. The facility has 10 conditioning chambers of which 2...

  11. Environmental Toxicology Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Fully-equipped facilities for environmental toxicology researchThe Environmental Toxicology Research Facility (ETRF) located in Vicksburg, MS provides over 8,200 ft...

  12. Ouellette Thermal Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Thermal Test Facility is a joint Army/Navy state-of-the-art facility (8,100 ft2) that was designed to: Evaluate and characterize the effect of flame and thermal...

  13. Projectile Demilitarization Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Projectile Wash Out Facility is US Army Ammunition Peculiar Equipment (APE 1300). It is a pilot scale wash out facility that uses high pressure water and steam...

  14. Challenges on preparing unitization agreements in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Marilda Rosado de Sa [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Faculdade de Direito; Appi, Valeria Tiriba [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2004-07-01

    As a further stage of the new oil and gas industry in Brazil, various challenges are now faced as an outcome from the O and G projects progress, under the legal framework in force in Brazil. Among all are the first unitization processes, which require a set of steps to be performed in order to achieve a unitization agreement. The paper aims at analyzing the legal, technical and drafting issues to be dealt with in such agreements. After a brief introduction to the general issues at stake in the unitization agreements the study shall encompass a follow up of the sequence of events to be complied with. One could mention the settlement of the criteria onto calculations to serve as guidelines for the negotiations will be based on. That, is usually based on concepts as oil in place, possible O and G in the reservoir, or reserve, which must be agreed by all involved parties. Another possible step to be considered is the creation of a common database, in order to permit fast decisions and optimise E and P operations in the unitized area. Other concerns should be addressed, depending on the amount of O and G to be produced from the unitized area, as: the avoidance of multiple redeterminations aiming to decrease unnecessary expenditures, which could jeopardize the arising project profitability; and the recalculations of Government take, royalties and other incumbencies, to be shared by all involved parties. The paper shall also mention the experience of other countries trying to adopt, where applicable and compatible with the best practices of the oil industry, solutions adopted where tradition in oil and gas is more mature. It should be considered that, in each bidding round the Brazilian Concession Agreement has undergone changes, therefore during an unitization process with two different versions of the Concession Agreement differences between corresponding clauses will have to be faced. Comments should also be made about satellite agreements, encompassing O and G buying

  15. Hydro and the Free Trade Agreement

    Energy Technology Data Exchange (ETDEWEB)

    Nehterton, A.

    This paper on the USA-Canada Free Trade Agreement considers the affect of the Agreement on Canadian electricity supplies and exports. The contentious issue involved stems from the level of long term control a purchaser of energy may gain over the exporter's resources; since electricity cannot be stored in very large quantity, a purchaser of such energy not only buys a quantity of energy but also the primary rights to use of an electrical generation capacity. This paper's concern is primarily with the level of firm energy contracts between Canadian and US utilities, and the danger that Canada could lose control of the use and benefits of the resource base. The Free Trade Agreement establishes a continental energy market whose entities are entitled to 'national treatment', i.e. foreign firms to be treated as domestic ones. The Agreement may mean increasing difficulty in repatriation of Canadian electricity capacity dedicated to the continental market, loss of national market integration if the current policy of requiring export prices to be no lower than domestic ones is overturned, lack of a means to overcome US internal regulatory interference to Canadian exports, and an overall tendency to lose the ability to shape trade and natural resources for national purposes. On the other hand, the Agreement can be the major political underpinning for new directions in energy investment.

  16. Virgin Islands Water and Power Authority Signs Legal Agreement with EPA and U.S. Department of Justice to Reduce Air Pollution at Two Power Plants

    Science.gov (United States)

    (WASHINGTON) Under an agreement announced today by the Environmental Protection Agency and the Department of Justice, the Virgin Islands Water and Power Authority (VIWAPA) will come into compliance with the federal Clean Air Act at its Krum Bay facility on

  17. Government Procurement Agreements and Telecommunications Business

    Directory of Open Access Journals (Sweden)

    Shin-Won Kang

    2001-12-01

    Full Text Available The opening of the telecommunications market is acceleration due to the world trends of deregulation and privatization under the WTO basic telecommunications agreements. Diversification of services and fast and efficient equipment procurement are becoming necessary conditions for the survival of telecommunications operators. However, the issue here is that telecommunications operators are still bound by the GPA (Government Procurement Agreement based on conditions of monopoly even though the procurement market in Korean is open substantially since 1997. Under such conditions, the continued application of the GPA on telecommunications operator who is highly competitive may result in a negative impact on the telecommunications business and quality of telecommunications service by undermining the autonomy of operator and decreasing operator’s procurement competitiveness. Therefore, this study examines the GPA and the issues raised by the agreement, and also attempts to suggest revisions or means of abrogating the unfair GPA with regards to the development and deregulation of the telecommunications business.

  18. THE APPROVAL OF THE SETTELMENT AGREEMENT BY ARBITRATION COURT, TAKING INTO ACCOUNT THE CONCLUDED MEDIATED AGREEMENT

    Directory of Open Access Journals (Sweden)

    Maslennikova L. V.

    2014-03-01

    Full Text Available The author analyses the issue of the relationship between mediated agreements and settlement and their legal inter-relationship, as well as critical comments regarding the lack of imperative requirements in Federal law of the Russian Federation of 27.07.2010 N 193-F3 "On alternative procedure for settling disputes with the use of an intermediary (mediation procedure" to the contents of the mediated settlement agreements which are subsequently endorsed by the arbitral court as settlement agreements

  19. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    Energy Technology Data Exchange (ETDEWEB)

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  20. The Post-Agreement Negotiation Process: The Problems of Ratifying International Environmental Agreements

    OpenAIRE

    Spector, B.I.; Korula, A.

    1992-01-01

    National ratification of international environmental agreements is a prime example of post-agreement negotiations. It is often the first subprocess in a larger process of sustained negotiations that occur after international accords are concluded, focused on implementation of those accords. Certainly, implementation of negotiated agreements involves legal, political, verification, and enforcement activities at both domestic and international levels. Many of these activities, including ratific...

  1. CNPC and CAS Sign Technological Cooperation Agreement

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ On August 16, 2006, China National Petroleum Corporation (CNPC) signed technological cooperation agreement with Chinese Academy of Sciences (CAS) at the Diaoyutai State Guesthouse in Beijing. Vice President of CNPC Zhou Jiping and Vice President of CAS Li Jiayang signed the agreement on behalf of both sides,marking a new era of unite brainstorm in petroleum technology. It will boost the development of petrochemical technology, especially the technology for the exploration and development of oil and gas field, engineering, oil refining and chemicals.

  2. Cooperative research and development agreements at METC

    Energy Technology Data Exchange (ETDEWEB)

    Ludlow, J.C.; Jarr, L.A.; Anderson, R.J.

    1995-06-01

    The Federal Technology Transfer Act of 1986 (P.L. 99-502) provided a new mechanism for joint research between private parties and the Morgantown Energy Technology Center (METC). Joint projects under this law are called Cooperative Research And Development Agreements (CRADAs) and are simply agreements between METC and the private sector to work together on a mutually beneficial project. Of primary interest to METC is the development and deployment of: (1) clean, efficient power generation technologies, (2) technologies for the characterization and exploitation of the Nation`s natural gas resource, and (3) environmental remediation technologies.

  3. Authenticated Key Agreement in Group Settings

    Institute of Scientific and Technical Information of China (English)

    LI Ming; WANG Yong; GU Da-wu; BAI Ying-cai

    2006-01-01

    An enhanced definition of implicit key authentication and a secure group key agreement scheme from pairings are presented. This scheme combines the merits of group public key and key trees to achieve a communication-efficient and authenticated group key agreement protocol. Besides, it avoids dependence on signature or MAC by involving member's long-term keys and short-term keys in the group key. Furthermore, the idea behind this design can be employed as a general approach to extend the authenticated two-party Diffie-Hellman protocols to group settings.

  4. Free Trade Agreements Are Cause for Hope

    Institute of Scientific and Technical Information of China (English)

    Financial Times

    2011-01-01

    @@ On October 21, three bilateral trade agreements have passed the US House of Representatives and Senate.But the votes came with a sense of relief rather than celebration from their supporters, and resignation rather than anger from their opponents. Very occasionally, common sense soars above political partisanship and economic short-termism to inspire hopeeven in the most jaded investor.The passing by US Congress of free trade agreements between America and Colombia, Panama and South Korea would be cause for celebration at the best of times.

  5. Car accidents and credit hire agreements

    OpenAIRE

    Rawlings, Philip; Wilson, Joanna

    2012-01-01

    A motorist whose car is damaged by the negligence of another may recover for the loss suffered, but must take reasonable steps to mitigate that loss. Where a replacement car is hired the charges can be recovered, if the car is needed for use and is similar to the damaged vehicle. Real difficulties arise if the motorist hires on credit. The agreement must comply with regulations applicable to credit\\ud agreements and constitute an enforceable contract, and, even then, full recovery of the char...

  6. Federal Facility Agreement Annual Progress Report for Fiscal Year 1999 Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel Jacobs Company LLC

    2000-01-01

    The U.S. Department of Energy-Oak Ridge Operations (DOE-ORO) EM Program adopted a watershed approach for performing Remedial Investigations (RIs) and characterizations for ORR because it is an effective system for determining the best methods for protecting and restoring aquatic ecosystems and protecting human health. The basic concept is that water quality and ecosystem problems are best solved at the watershed level rather than at the individual water-body or discharger level. The watershed approach requires consideration of all environmental concerns, including needs to protect public health, critical habitats such as wetlands, biological integrity, and surface and ground waters. The watershed approach provides an improved basis for management decisions concerning contaminant sources and containment. It allows more direct focus by stakeholders on achieving ecological goals and water quality standards rather than a measurement of program activities based on numbers of permits or samples. The watershed approach allows better management strategies for investigations, therefore maximizing the utilization of scarce resources. Feasibility studies (FSs) evaluate various alternatives in terms of environmental standards, the protection of human health and the environment, and the costs of implementation to find the optimum solution among them. Society has to decide how much it is willing to spend to meet the standards and to be protective. Conducting FSs is the process of trading off those criteria to pick that optimum point that society wants to achieve. Performing this analysis at the watershed scale allows those trade-offs to be made meaningfully. In addition, a Land Use Control Assurance Plan for the ORR was prepared to identify the strategy for assuring the long-term effectiveness of land use controls. These land use controls will be relied upon to protect human health and the environment at areas of the ORR undergoing remediation pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act and/or the Resource Conservation and Recovery Act. This plan will be implemented by means of a Memorandum of Understanding (MOU) incorporating its terms with the United States EPA and TDEC. The majority of projects described in this report are grouped into five watersheds. They are the East Tennessee Technical Park (ETTP) Watershed (formerly the K-25 Site), the Melton Valley (MV) and Bethel Valley (BV) Watersheds at the Oak Ridge National Laboratory (ORNL), and the Bear Creek Valley (BCV) and Upper East Fork Poplar Creek (UEFPC) Watersheds at the Y-12 Plant.

  7. Changes of Serum FFA,Hcy and CysC Levels in Diabetic Nephropathies Patients in Different Stages%不同分期糖尿病肾病患者血清游离脂肪酸、同型半胱氨酸和胱抑素C水平变化

    Institute of Scientific and Technical Information of China (English)

    陈薇; 童秀峰; 黎安玲; 胡汉宁

    2014-01-01

    目的:观察不同分期糖尿病肾病(DN)患者血清游离脂肪酸(FFA)、同型半胱氨酸(Hcy)、胱抑素 C(CysC)等水平变化及与尿微量白蛋白排泄率(UAER)的相关性。方法:2型糖尿病(T2DM)患者178例,根据24h UAER分为单纯T2DM组(DM组,n=82)、早期DN组(EDN,n=56);临床DN组(CDN,n=40例);同期体检健康者作为对照组(n=42)。采用全自动生化分析仪测定各组血清 FFA(酶法)、Hcy(循环酶法)、CysC(免疫增强比浊法)、尿素氮(Urea,酶法)、肌酐(Cr,酶法)含量,采用全自动特种蛋白分析仪测定 UAER,比较各组各指标水平差异,分析EDN、CDN组患者 FFA、Hcy、CysC与 UAER的相关性。结果:EDN 组和 CDN 组血清 FFA、Hcy、CysC 水平高于DM组和对照组(P均 EDN group > DM group > control group(P < 0.05).Correlation analysis showed that blood FFA,Hcy,CysC and UAER had high degree of positive correlation between EDN group and CDN group(P <0.01).Conclusion:The development of DN was closely related to the increase of FFA,Hcy and CysC levels.

  8. Exploring hubness in Regional Trade Agreements

    NARCIS (Netherlands)

    Vaal, A. de

    2016-01-01

    In the plethora of Regional Trade Agreements (RTAs) some countries take in a more central position than others in the sense that some countries are much more engaged with other countries through RTAs. Furthermore, the position of some countries is that of a hub: they have (many) trade

  9. 48 CFR 31.109 - Advance agreements.

    Science.gov (United States)

    2010-10-01

    ... sampling methodologies at 31.201-6(c). However, an advance agreement is not an absolute requirement and the...) Precontract costs; (5) Independent research and development and bid and proposal costs; (6) Royalties and...) Professional services (e.g., legal, accounting, and engineering); (13) General and administrative costs...

  10. 76 FR 51033 - Notice of Agreement Filed

    Science.gov (United States)

    2011-08-17

    .... Synopsis: The amendment provides authority for the corporate restructuring of Consolidated Chassis... inland carriers to participate in pool governances; and authorizes pools formed under the Agreement, upon... carriers, shippers and others and to develop terms of use and charges for such interchanged chassis....

  11. 77 FR 282 - Proposed Settlement Agreement

    Science.gov (United States)

    2012-01-04

    ... above. FOR FURTHER INFORMATION CONTACT: Michael Horowitz, Air and Radiation Law Office (2344A), Office... . SUPPLEMENTARY INFORMATION: I. Additional Information About the Proposed Settlement Agreement This proposed... electrical blackout, such as unusually low frequency, equipment overload, capacity or energy deficiency, or...

  12. 18 CFR 401.33 - Administrative agreements.

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Project Review Under Section 3.8 of the Compact § 401.33 Administrative agreements. The Executive Director is authorized and directed to enter into cooperative... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Administrative...

  13. 45 CFR 1611.9 - Retainer agreements.

    Science.gov (United States)

    2010-10-01

    ... Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION FINANCIAL ELIGIBILITY § 1611.9 Retainer agreements. (a) When a recipient provides extended service to a client, the... practices in the recipient's service area and shall include, at a minimum, a statement identifying the legal...

  14. 22 CFR 33.5 - Guaranty agreements.

    Science.gov (United States)

    2010-04-01

    ... will provide for reimbursement for certain losses caused by foreign countries' seizure and detention of U.S. fishing vessels on the basis of claims to jurisdiction which are not recognized by the United..., be transferred when a vessel which is the subject of a guaranty agreement is transferred to a...

  15. 77 FR 3773 - Notice of Agreement Filed

    Science.gov (United States)

    2012-01-25

    ....: 012061-003. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Western Mediterranean-U.S. East Coast. Parties: CMA CGM, S.A. and A.P. Moller-Maersk A/S. Filing Party: Mark E....

  16. 76 FR 63618 - Notice of Agreements Filed

    Science.gov (United States)

    2011-10-13

    ...: Transpacific Stabilization Agreement. Parties: American President Lines, Ltd. and APL Co. PTE Ltd.; (operating as a single carrier); A.P. Moller-Maersk A/S trading as Maersk Line; China Shipping Container Lines (Hong Kong) Company Limited and China Shipping Container Lines Company Limited (operating as a...

  17. 77 FR 50688 - Notice of Agreement Filed

    Science.gov (United States)

    2012-08-22

    ....: 012084-001. Title: HLAG/Maersk Line Gulf-South America Slot Charter Agreement. Parties: A.P. Moller-Maersk A/S and Hapag-Lloyd AG. Filing Party: Wayne R. Rohde, Esq.; Cozen O'Connor; 1627 I Street...

  18. 75 FR 80499 - Notice of Agreement Filed

    Science.gov (United States)

    2010-12-22

    ... No.: 012108-001. Title: The World Liner Data Agreement. Parties: ANL Container Line Pty Ltd.; A.P. Moller-Maersk A/S; CMA CGM S.A.; Compania Chilena de Navegacion Interoceanica S.A.; Hamburg- Sud; Hapag-Lloyd AG; Mediterranean Shipping Company S.A.; Orient Overseas Container Line Ltd.; and United...

  19. 78 FR 35270 - Notice of Agreements Filed

    Science.gov (United States)

    2013-06-12

    ...: Transpacific Stabilization Agreement. Parties: American President Lines, Ltd. and APL Co. PTE Ltd. (operating as a single carrier); A.P. Moller-Maersk A/S trading under the name of Maersk Line; China Shipping... Services LLC; Hybur Ltd.; Seaboard Marine, Ltd.; Seafreight Line, Ltd.; Tropical Shipping and...

  20. 75 FR 51073 - Notice of Agreement Filed

    Science.gov (United States)

    2010-08-18

    ... No.: 011733-029. Title: Common Ocean Carrier Platform Agreement. Parties: A.P. Moller-Maersk A/S; American President Lines, Ltd., APL Co., PTE Ltd.; CMA CGM; Hamburg-S d; Hapag-Lloyd AG; Mediterranean... Navegacao e Logistica Ltda.; China Shipping Container Lines Company Limited; Compania Sud Americana...

  1. 77 FR 76482 - Notice of Agreement Filed

    Science.gov (United States)

    2012-12-28

    ... Stabilization Agreement. Parties: American President Lines, Ltd. and APL Co. PTE Ltd.; (operating as a single carrier); A.P. Moller-Maersk A/S trading as Maersk Line; China Shipping Container Lines (Hong Kong) Company Limited and China Shipping Container Lines Company Limited (operating as a single carrier);...

  2. 78 FR 72890 - Notice of Agreements Filed

    Science.gov (United States)

    2013-12-04

    .... & Cia.; A.P. Moller- Maersk A/S trading under the name of Maersk Line; China Shipping Container Lines Co...: HLAG/Maersk Line Gulf-South America Slot Charter Agreement. Parties: A.P. Moller-Maersk A/S and Hapag... Sud Americana de Vapores, S.A.; COSCO Container Lines Company Limited; Dole Ocean Cargo...

  3. 77 FR 69842 - Notice of Agreement Filed

    Science.gov (United States)

    2012-11-21

    ....: 012057-008. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Asia to USEC and PNW-Suez/PNW & Panama Loops. Parties: A.P. Moller-Maersk A/S and CMA CGM S.A. Filing...

  4. 76 FR 74060 - Notice of Agreements Filed

    Science.gov (United States)

    2011-11-30

    ... Co. Pte Ltd.; American President Lines, Ltd.; A.P. Moller-Maersk A/S; ANL Singapore Pte Ltd.; China Shipping Container Lines Co., Ltd.; CMA CGM, S.A.; Companhia Libra de Navegacao; Compa a Chilena de....: 012057-006. Title: CMA CGM/Maersk Line Space Charter, Sailing and Cooperative Working Agreement Asia...

  5. 75 FR 11180 - Notice of Agreements Filed

    Science.gov (United States)

    2010-03-10

    ... allocation within defined limits. Agreement No.: 012032-004. Title: CMA CGM/MSC/Maersk Line North and Central.... Moller-Maersk A/S, CMA CGM S.A., and Mediterranean Shipping Company S.A. Filing Party: Wayne R....

  6. The Paris agreement: one year after

    Science.gov (United States)

    Jouzel, J.

    2016-12-01

    Even if there is an important gap between the nationally determined contributions and the 2°C objective - of the order of 15 gigatonnes CO2 equivalent in 2030 - the agreement adopted in Paris last december (COP21) is largely considered as a success. This can be explained by the fact that this agreement - now signed by practically all countries - comes after the partial failure of the Kyoto protocol (COP3) - which has not been ratified by the US, the first emitting country in the late nineties - and the lack of ambition of the Copenhagen agreement (COP15). One year after COP21, the COP of « decision » and a few weeks after COP22, the COP of « action » to be held in Marrakech, it will be interesting to see if the Paris momentum has been kept. Is the ratification of the agreement, which requires 55 countries representing at least 55 of global emissions, under way ? Are there signs of stabilization of greenhouse gas emissions and some hope of increased ambition in terms of reduction of emissions after 2020 ? The 1°5 °C objective which will be the focus of an IPCC special report to be published in 2018 will also be discussed.

  7. 78 FR 28596 - Notice of Agreement Filed

    Science.gov (United States)

    2013-05-15

    ....: 012207. Title: CMA CGM/APL Slot Exchange Agreement, North Europe & Westmed--U.S. Gulf and East Coast... exchange space ] with each other in the trade between the U.S. East and Gulf Coasts on the one hand, and Netherlands, Germany, Belgium, the United Kingdom, Morocco, Malta, Italy, France, Portugal, and Spain on...

  8. 77 FR 24712 - Notice of Agreements Filed

    Science.gov (United States)

    2012-04-25

    ... Singapore, Spain, Morocco and the U.S. East Coast and modifies the number of slots to be exchanged in other... connection with the carriage of cargo between Vietnam, China, Singapore, and the U.S. East Coast. Agreement..., Korea, Vietnam, Singapore, Sri Lanka, Egypt, the United Arab Emirates, Spain, Morocco, and the U.S....

  9. 75 FR 70005 - Notice of Agreement Filed

    Science.gov (United States)

    2010-11-16

    ... operations, including RFID technology; obtain and administer government grants to fund technology-related activities; meet with stakeholders to discuss deployment of RFID technologies; and to establish and manage an entity to implement and administer agreements reached regarding RFID and/or other similar technologies...

  10. On the Drafting of Confidentiality Agreements

    DEFF Research Database (Denmark)

    Drewsen, Merete; Lando, Henrik; Cummins, Tim

    2006-01-01

    IACCM (International Association for Contract and Commercial Management) has initiated. The main theoretical aspect of the article concerns the application of the value maximization principle (the Coase theorem) to the drafting of confidentiality agreements. While the article is not theoretical, its...

  11. Agreement and the structure of relative clauses

    Directory of Open Access Journals (Sweden)

    Boban Arsenijević

    2016-07-01

    Full Text Available The paper proposes an account of asymmetries in agreement patterns that obtain in restrictive and non-restrictive relative clauses headed by hybrid agreement nouns 'd(jeca '‘children’, 'braća '‘brothers’, and 'gospoda '‘gentry’ in Bosnian/Croatian/Serbian (BCS. We note that relative clauses headed by hybrid nouns display different possibilities of agreement morphology on the relative pronoun 'koji/a/e '‘which’, depending, on the one hand, on whether the relative clause is restrictive or non-restrictive and on the other, on the case of the relative pronoun. We argue that the observed differences are the result of a conspiracy of the following factors: (i hybrid number-agreement nouns introduce a null plural pronoun unspecified for gender (Postal 1966; den Dikken 2001; Torrego and Laga 2015, (ii all plural case forms of the relative pronoun except for nominative and accusative show full gender syncretism (Alsina and Arsenijević 2012b, and (iii non-restrictive relative clauses involve a null definite pronoun and attach to the head noun higher than the restrictive relative clauses (Postal 1994; de Vries 2002; 2006. We maintain that the facts discussed in the paper argue against analyses which derive the differences between restrictive and non-restrictive relative clauses from their LF representations, rather than from their overt syntax.

  12. 33 CFR 385.16 - Design agreements.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Design agreements. 385.16 Section 385.16 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN CERP...

  13. Making Education Markets through Global Trade Agreements

    Science.gov (United States)

    Robertson, Susan L.

    2017-01-01

    This paper uses the global trade negotiations and agreements, which include education sectors as potentially tradable services, to show the complex processes at work in making global education markets. Drawing on the work of Jens Beckert and others, I focus on the micro-processes of making capitalist orders and the challenges at hand in bringing…

  14. Environmental Voluntary Agreements in the Dutch Context

    NARCIS (Netherlands)

    Bressers, Johannes T.A.; de Bruijn, Theo; Croci, Edoardo

    2005-01-01

    This paper describes and analyses the use of environmental voluntary agreements, or covenants, in Dutch environmental policy. Covenants have become a widely used policy instrument in the Netherlands. This trend reinforces the strong neo-corporatist traits of Dutch society with its tendency towards

  15. 78 FR 75345 - Notice of Agreements Filed

    Science.gov (United States)

    2013-12-11

    ...: Compania Sud Americana de Vapores S.A. and Trans Global Shipping NV. Filing Party: Walter H. Lion Esq.; Mc... Agreement. Parties: Swordfish Shipping Inc. and Trans Global Shipping NV. Filing Party: Walter H. Lion, Esq... York and New Jersey. Parties: New York Shipping Association, Inc. and the International...

  16. Facility Effluent Monitoring Plan determinations for the 600 Area facilities

    Energy Technology Data Exchange (ETDEWEB)

    Nickels, J.M.

    1991-08-01

    This document determines the need for Facility Effluent Monitoring Plans for Westinghouse Hanford Company's 600 Area facilities on the Hanford Site. The Facility Effluent Monitoring Plan determinations were prepared in accordance with A Guide For Preparing Hanford Site Facility Effluent Monitoring Plans (WHC 1991). Five major Westinghouse Hanford Company facilities in the 600 Area were evaluated: the Purge Water Storage Facility, 212-N, -P, and -R Facilities, the 616 Facility, and the 213-J K Storage Vaults. Of the five major facilities evaluated in the 600 Area, none will require preparation of a Facility Effluent Monitoring Plan.

  17. Design of safeguards information treatment system at the facility level

    Energy Technology Data Exchange (ETDEWEB)

    Song, Dae Yong; Lee, Byung Doo; Kwack, Eun Ho; Choi, Young Myong

    2001-05-01

    We are developing Safeguards Information Treatment System at the facility level(SITS) to manage synthetically safeguards information and to implement efficiently the obligations under the Korea-IAEA Safeguards Agreement, bilateral agreements with other countries and domestic law. In this report, we described the contents of the detailed design of SITS such as database, I/O layout and program. In the present, we are implementing the SITS based on the contents of the design of SITS, and then we plan to provide the system for the facilities after we finish implementing and testing the system.

  18. Synchrotron radiation facilities

    CERN Multimedia

    1972-01-01

    Particularly in the past few years, interest in using the synchrotron radiation emanating from high energy, circular electron machines has grown considerably. In our February issue we included an article on the synchrotron radiation facility at Frascati. This month we are spreading the net wider — saying something about the properties of the radiation, listing the centres where synchrotron radiation facilities exist, adding a brief description of three of them and mentioning areas of physics in which the facilities are used.

  19. Thermal distortion test facility

    Science.gov (United States)

    Stapp, James L.

    1995-02-01

    The thermal distortion test facility (TDTF) at Phillips Laboratory provides precise measurements of the distortion of mirrors that occurs when their surfaces are heated. The TDTF has been used for several years to evaluate mirrors being developed for high-power lasers. The facility has recently undergone some significant upgrades to improve the accuracy with which mirrors can be heated and the resulting distortion measured. The facility and its associated instrumentation are discussed.

  20. US-Canada Free-Trade Agreement

    Energy Technology Data Exchange (ETDEWEB)

    1988-02-01

    The US-Canada Free Trade Agreement is an historic agreement that will yield major benefits for the US and Canadian economies, for US-Canadian bilateral trade relations, and for the international trade regime. The energy section of the Agreement is one of its most important. Energy trade between the US and Canada amounts to over $10 billion per year, the largest such bilateral trade in the world. Canada is our largest oil supplier and provides virtually all of our natural gas and electricity imports. While these volumes are a small fraction of US needs, they provide an important margin of energy security. Canada also is an important market for US energy exports, buying 16 million tons or $700 million worth of coal in 1987, 20% of US coal exports. The Free Trade Agreement ensures that the US and Canada can continued to enjoy unrestricted trade in energy, provides benefits to US consumers and producers, and enhances our energy security. The Agreement: prohibits future restrictions on energy trade, such as quantitative restriction, import or export taxes, and minimum prices; ensures that US consumers will be treated equitably with Canadian consumers; provides added assurance of supply in the event of disruptions; will lower costs to consumers, including our energy intensive industries, and help make US industry more competitive in world markets; will provide more certainty to producers and consumers, which should expand energy trade and be more conducive to energy investment; and will, over time, reduce US oil imports by encouraging continued market penetration of Canadian and US natural gas, and greater use of Canadian hydroelectric power.

  1. 48 CFR 225.403 - World Trade Organization Government Procurement Agreement and Free Trade Agreements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false World Trade Organization Government Procurement Agreement and Free Trade Agreements. 225.403 Section 225.403 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Trade...

  2. What’s in an Agreement? A Formal Analysis and an extension of WS-Agreement

    NARCIS (Netherlands)

    Aiello, Marco; Frankova, Ganna; Malfatti, Daniela

    2005-01-01

    Non-functional properties of services and service compositions are of paramount importance for the success of web services. The negotiation of non-functional properties between web service provider and consumer can be agreed on a priori, by specifying an agreement. WS-Agreement is a recently propose

  3. Materials Characterization Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Materials Characterization Facility enables detailed measurements of the properties of ceramics, polymers, glasses, and composites. It features instrumentation...

  4. Mobile Solar Tracker Facility

    Data.gov (United States)

    Federal Laboratory Consortium — NIST's mobile solar tracking facility is used to characterize the electrical performance of photovoltaic panels. It incorporates meteorological instruments, a solar...

  5. Universal Drive Train Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This vehicle drive train research facility is capable of evaluating helicopter and ground vehicle power transmission technologies in a system level environment. The...

  6. Composite Structures Manufacturing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Composite Structures Manufacturing Facility specializes in the design, analysis, fabrication and testing of advanced composite structures and materials for both...

  7. Neutron Therapy Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Neutron Therapy Facility provides a moderate intensity, broad energy spectrum neutron beam that can be used for short term irradiations for radiobiology (cells)...

  8. Catalytic Fuel Conversion Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility enables unique catalysis research related to power and energy applications using military jet fuels and alternative fuels. It is equipped with research...

  9. Heated Tube Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Heated Tube Facility at NASA GRC investigates cooling issues by simulating conditions characteristic of rocket engine thrust chambers and high speed airbreathing...

  10. Engine Test Facility (ETF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Air Force Arnold Engineering Development Center's Engine Test Facility (ETF) test cells are used for development and evaluation testing of propulsion systems for...

  11. High Combustion Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — At NETL's High-Pressure Combustion Research Facility in Morgantown, WV, researchers can investigate new high-pressure, high-temperature hydrogen turbine combustion...

  12. Region 9 NPDES Facilities

    Data.gov (United States)

    U.S. Environmental Protection Agency — Point geospatial dataset representing locations of NPDES Facilities. NPDES (National Pollution Discharge Elimination System) is an EPA permit program that regulates...

  13. Geospatial Data Analysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Geospatial application development, location-based services, spatial modeling, and spatial analysis are examples of the many research applications that this facility...

  14. Geodynamics Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This GSL facility has evolved over the last three decades to support survivability and protective structures research. Experimental devices include three gas-driven...

  15. Imagery Data Base Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Imagery Data Base Facility supports AFRL and other government organizations by providing imagery interpretation and analysis to users for data selection, imagery...

  16. Pavement Testing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Comprehensive Environmental and Structural Analyses The ERDC Pavement Testing Facility, located on the ERDC Vicksburg campus, was originally constructed to provide...

  17. Nonlinear Materials Characterization Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Nonlinear Materials Characterization Facility conducts photophysical research and development of nonlinear materials operating in the visible spectrum to protect...

  18. Geophysical Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Geophysical Research Facility (GRF) is a 60 ft long qaodmasdkwaspemas5ajkqlsmdqpakldnzsdfls 22 ft wide qaodmasdkwaspemas4ajkqlsmdqpakldnzsdfls 7 ft deep concrete...

  19. Transonic Experimental Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Transonic Experimental Research Facility evaluates aerodynamics and fluid dynamics of projectiles, smart munitions systems, and sub-munitions dispensing systems;...

  20. Flexible Electronics Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Flexible Electronics Research Facility designs, synthesizes, tests, and fabricates materials and devices compatible with flexible substrates for Army information...

  1. DUPIC facility engineering

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. J.; Lee, H. H.; Kim, K. H. and others

    2000-03-01

    The objectives of this study are (1) the refurbishment for PIEF(Post Irradiation Examination Facility) and M6 hot-cell in IMEF(Irradiated Material Examination Facility), (2) the establishment of the compatible facility for DUPIC fuel fabrication experiments which is licensed by government organization, and (3) the establishment of the transportation system and transportation cask for nuclear material between facilities. The report for this project describes following contents, such as objectives, necessities, scope, contents, results of current step, R and D plan in future and etc.

  2. Textiles Performance Testing Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Textiles Performance Testing Facilities has the capabilities to perform all physical wet and dry performance testing, and visual and instrumental color analysis...

  3. Joint Computing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Raised Floor Computer Space for High Performance Computing The ERDC Information Technology Laboratory (ITL) provides a robust system of IT facilities to develop and...

  4. GPS Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Global Positioning System (GPS) Test Facility Instrumentation Suite (GPSIS) provides great flexibility in testing receivers by providing operational control of...

  5. Magnetics Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Magnetics Research Facility houses three Helmholtz coils that generate magnetic fields in three perpendicular directions to balance the earth's magnetic field....

  6. Target Assembly Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Target Assembly Facility integrates new armor concepts into actual armored vehicles. Featuring the capability ofmachining and cutting radioactive materials, it...

  7. Facility Environmental Management System

    Data.gov (United States)

    Federal Laboratory Consortium — This is the Web site of the Federal Highway Administration's (FHWA's) Turner-Fairbank Highway Research Center (TFHRC) facility Environmental Management System (EMS)....

  8. Proximal Probes Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Proximal Probes Facility consists of laboratories for microscopy, spectroscopy, and probing of nanostructured materials and their functional properties. At the...

  9. Manufacturing Demonstration Facility (MDF)

    Data.gov (United States)

    Federal Laboratory Consortium — The U.S. Department of Energy Manufacturing Demonstration Facility (MDF) at Oak Ridge National Laboratory (ORNL) provides a collaborative, shared infrastructure to...

  10. Pavement Testing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Comprehensive Environmental and Structural AnalysesThe ERDC Pavement Testing Facility, located on the ERDC Vicksburg campus, was originally constructed to provide an...

  11. The National Ignition Facility project

    Energy Technology Data Exchange (ETDEWEB)

    Paisner, J.A.; Boyes, J.D.; Kumpan, S.A.; Sorem, M.

    1996-06-01

    The Secretary of the U.S. Department of Energy (DOE) commissioned a Conceptual Design Report (CDR) for the National Ignition Facility (NIF) in January 1993 as part of a Key Decision Zero (KD0), justification of Mission Need. Motivated by the progress to date by the Inertial Confinement Fusion (ICF) program in meeting the Nova Technical Contract goals established by the National Academy of Sciences in 1989, the Secretary requested a design using a solid-state laser driver operating at the third harmonic (0.35 {mu}m) of neodymium (Nd) glass. The participating ICF laboratories signed a Memorandum of Agreement in August 1993, and established a Project organization, including a technical team from the Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL), Sandia National Laboratories (SNL), and the Laboratory for Laser Energetics at the University of Rochester. Since then, the authors completed the NIF conceptual design, based on standard construction at a generic DOE Defense Program`s site, and issued a 7,000-page, 27-volume CDR in May 1994. Over the course of the conceptual design study, several other key documents were generated, including a Facilities Requirements Document, a Conceptual Design Scope and Plan, a Target Physics Design Document, a Laser Design Cost Basis Document, a Functional Requirements Document, an Experimental Plan for Indirect Drive Ignition, and a Preliminary Hazards Analysis (PHA) Document. DOE used the PHA to categorize the NIF as a low-hazard, non-nuclear facility. This article presents an overview of the NIF project.

  12. 46 CFR 535.403 - Form of agreements.

    Science.gov (United States)

    2010-10-01

    ... AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE SHIPPING ACT OF 1984 Filing of Agreements § 535.403 Form of agreements. The requirements of this section apply to all agreements except marine.... Agreements in a language other than English shall be accompanied by an English translation. (b)...

  13. 75 FR 54352 - Agency Information Collection Activities: Free Trade Agreements

    Science.gov (United States)

    2010-09-07

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Free Trade Agreements... Agreements. OMB Number: 1651-0117. Form Number: None. Abstract: Free trade agreements are established to... further cooperation to expand and enhance benefits of the agreement. Free trade agreements establish free...

  14. Positron Emission Tomography (PET) Experience with 2-[18F]Fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[18F]FA) in the Living Human Brain of Smokers with Paranoid Schizophrenia

    Science.gov (United States)

    BRAŠIĆ, JAMES ROBERT; CASCELLA, NICOLA; KUMAR, ANIL; ZHOU, YUN; HILTON, JOHN; RAYMONT, VANESSA; CRABB, ANDREW; GUEVARA, MARIA RITA; HORTI, ANDREW G.; WONG, DEAN FOSTER

    2012-01-01

    Utilizing postmortem data (Breese, et al., 2000), we hypothesized that the densities of high-affinity neuronal α4β2 nicotinic acetylcholine receptors (nAChRs) in the brain exist in a continuum from highest to lowest as follows: smokers without schizophrenia > smokers with schizophrenia > nonsmokers without schizophrenia > nonsmokers with schizophrenia. Application of the Kruskal-Wallis Test (Stata, 2003) to the postmortem data (Breese, et al., 2000) confirmed the hypothesized order in the cortex and the hippocampus and attained significance in the caudate and the thalamus. Positron emission tomography (PET) was performed for 60 minutes at 6 hours after the intravenous administration of 444 megabequerels [MBq] (12 mCi) 2-[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[18F]FA), a radiotracer for high-affinity neuronal α4β2 nAChRs, as a bolus plus continuous infusion to 10 adults (7 men and 3 women) (6 smokers including 5 with paranoid schizophrenia and 4 nonsmokers) ranging in age from 22 to 56 years (mean 40.1, standard deviation 13.6). The thalamic nondisplaceable binding potential (BPND) was 1.32 ± 0.19 (mean ± standard deviation) for healthy control nonsmokers; 0.50 ± 0.19 for smokers with paranoid schizophrenia; and 0.51 for the single smoker without paranoid schizophrenia. The thalamic BPNDs of nonsmokers were significantly higher than those of smokers who smoked cigarettes a few hours before the scans (P = 0.0105) (StataCorp, 2003), which was likely due to occupancy of nAChRs by inhaled nicotine in smokers. Further research is needed to rule out the effects of confounding variables. PMID:22169936

  15. Agreement dynamics on directed random graphs

    CERN Document Server

    Lipowski, Adam; Ferreira, Antonio L

    2016-01-01

    When agreement-dynamics models are placed on a directed random graph, a fraction of sites $\\exp(-z)$, where $z$ is the average degree, becomes permanently fixed or flickering. In the Voter model, which has no surface tension, such zealots or flickers freely spread their opinions and that makes the system disordered. For models with a surface tension, like the Ising model or the Naming Game model, their role is limited and such systems are ordered at large~$z$. However, when $z$ decreases, the density of zealots or flickers increases, and below a certain threshold ($z\\sim 1.9-2.0$) the system becomes disordered. Our results show that the agreement dynamics on directed networks is much different from their undirected analogues.

  16. Authenticating Tripartite Key Agreement Protocol with Pairings

    Institute of Scientific and Technical Information of China (English)

    Sheng-Li Liu; Fang-Guo Zhang; Ke-Fei Chen

    2004-01-01

    In this paper, an authenticated tripartite key agreement protocol is proposed, which is an ID-based one with pairings. This protocol involves only one round. The authenticity of the protocol is assured by a special signature scheme, so that messages carrying the information of two ephemeral keys can be broadcasted authentically by an entity. Consequently, one instance of the protocol results in eight session keys for three entities. In other word, one instance of the protocol generates a session key, which is eight times longer than those obtained from traditional key agreement protocols. Security attributes of the protocol are presented, and the computational overhead and bandwidth of the broadcast messages are analyzed as well.

  17. FETC/EPRI BIOMASS COFIRING COOPERATIVE AGREEMENT

    Energy Technology Data Exchange (ETDEWEB)

    D. TILLMAN; E. HUGHES

    1998-08-01

    This quarter much progress was made in promoting cofiring through the many FETC/EPRI backed projects. During January 1, 1998 to March 31st, 1998 significant contractual agreements were arranged for future testing and analyses of previous testing were conducted. Most notable was the analysis done on the testing run at the Tennessee Valley Authority�s Colbert Fossil Plant that showed no significant impacts to the plant boiler due to cofiring. Northern Indiana Public Service Company also identified Bailly #7 as the site of the next series of tests using their plants. Other work done on these projects primarily focused on continued cofiring development. This report summarizes the activities during the first quarter in 1998 of the FETC/EPRI Biomass Cofiring Cooperative Agreement. It focuses upon reporting the results of testing in order to highlight the progress at utilities.

  18. DUPIC facility engineering

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. J.; Lee, H. H.; Kim, K. H. [and others

    2002-03-01

    With starting DUPIC fuel fabrication experiment by using spent fuels, 1) operation and refurbishment for DFDF (DUPIC fuel development facility), and 2) operation and improvement of transportation equipment for radioactive materials between facilities became the objectives of this study. This report describes objectives of the project, necessities, state of related technology, R and D scope, R and D results, proposal for application etc.

  19. Samarbejdsformer og Facilities Management

    DEFF Research Database (Denmark)

    Storgaard, Kresten

    Resultater fra en surveyundersøgelse om fordele og ulemper ved forskellige samarbejdsformer indenfor Facilities Management fremlægges.......Resultater fra en surveyundersøgelse om fordele og ulemper ved forskellige samarbejdsformer indenfor Facilities Management fremlægges....

  20. Japan Hadron Facility

    CERN Document Server

    Hayano, R S

    1999-01-01

    Japan Hadron Facility (JHF) is a high-intensity proton accelerator complex consisting of a 200 MeV linac, a 3 GeV booster and a 50 GeV main ring. Its status and future possibilities of realizing a versatile antiproton facility at JHF are presented.

  1. Samarbejdsformer og Facilities Management

    DEFF Research Database (Denmark)

    Storgaard, Kresten

    Resultater fra en surveyundersøgelse om fordele og ulemper ved forskellige samarbejdsformer indenfor Facilities Management fremlægges.......Resultater fra en surveyundersøgelse om fordele og ulemper ved forskellige samarbejdsformer indenfor Facilities Management fremlægges....

  2. BIBLIOGRAPHY OF FACILITIES INFORMATION.

    Science.gov (United States)

    American Association of Junior Colleges, Washington, DC.

    PERSONNEL OF THE FACILITIES INFORMATION SERVICE OF THE AMERICAN ASSOCIATION OF JUNIOR COLLEGES COMPILED THIS LISTING OF BOOKS, ARTICLES, MONOGRAPHS, AND OTHER PRINTED MATERIALS RELEVANT TO JUNIOR COLLEGE FACILITIES PLANNING, DESIGN, AND CONSTRUCTION. IN ADDITION TO A "GENERAL" CATEGORY, REFERENCES ARE GROUPED UNDER HEADINGS OF AUDITORIUMS, COLLEGE…

  3. A quarter of a century of function assignment agreements with the autonomous communities. The; Los acuerdos de encomienda con las comunidades autonomas cumplen un cuarto de siglo

    Energy Technology Data Exchange (ETDEWEB)

    Montero Sanchez, M. A.; Rodriguez Marti, M.; Urbano Pollato, I.; Zamora Martin, F.

    2010-07-01

    The CN has the power to commission certain radioactive facility surveillance and inspection functions to the autonomous communities through an agreement between the Council and the regional government in question. The first of these agreements was signed in 1985 with the Regional Government of Catalonia, and during the 25 years that have passed since then similar agreements have been signed with eight other communities: Asturias, the Balearic Islands, the Canary Islands, Galicia, Murcia, Navarra, the Basque Country and the Community of Valencia. (Author)

  4. Signalling in international environmental agreements. Using pre-agreement emission level as a signalling device

    Energy Technology Data Exchange (ETDEWEB)

    Steiner, U.

    1997-12-31

    This paper addresses the question about strategic incentives in international environmental agreements and tries to give a positive description of how the design of the agreement influences the strategic behaviour of potential participants before they enter the treaty. A common feature of the design of agreements is that the reduction obligations (RO) are made contingent on a pre-agreement or baseline emission. As it is assumed that countries posses better information about their reduction costs than does the international body in charge of deciding the RO, countries might have incentives to signal higher costs by increasing their baseline emission, and thereby reducing the costs of entering the agreement. The appropriate analytical framework is to use a signalling game approach, where the pre-agreement emission level conveys information about the privately informed country`s reduction cost. In this paper two types of agreement design are considered, one with uniform obligations, and one with differentiated obligations. This enables us to make a comparison between two different reduction regimes. The result is that the predicted outcomes vary with regard to both the environmental effectiveness and the associated expected costs for the participating countries. This means that when private information is considered, the anticipation of a given institutional framework has significant impact on the resulting distortion of the total emission level, highlighting the necessity of taking this into consideration when future designs are proposed. (au)

  5. 78 FR 5440 - Notice of Agreements Filed

    Science.gov (United States)

    2013-01-25

    ...-Maersk A/S; China Shipping Container Lines Co., Ltd.; CMA CGM, S.A.; Compa a Chilena de Navegaci n... amendment deletes Safmarine Container Lines N.V. as a subsidiary of A.P. Moller-Maersk A/S. Agreement No...-Maersk AS, trading under the name Maersk Line; CMA CGM, S.A./ANL Singapore Pte Ltd. (acting as a...

  6. Service-level agreements. Trading places.

    Science.gov (United States)

    Freer, J; Gray, C

    1997-10-16

    Internal trading or service-level agreements can help trusts manage the interface between hospital consultants and support services. Previous attempts at introducing SLAs had increased the administrative burden on support departments without changing consultants' behaviour or improving budgetary control. Problems were resolved by simplifying and improving measuring and reporting systems to produce credible, user-friendly information that facilitates meaningful debate between clinical managers and support services.

  7. Continuous Variable Solution for Byzantine Agreement

    CERN Document Server

    Neigovzen, R; Neigovzen, Rodion; Sanpera, Anna

    2005-01-01

    We demonstrate that the Byzantine Agreement Problem (BAP) in its weaker version with detectable broadcast, can be solved using continuous variables Gaussian states with Gaussian operations. The protocol uses genuine tripartite symmetric entanglement, but differs from protocols proposed for qutrits or qubits. Contrary to the quantum key distribution (QKD) which is possible with all Gaussian states, for the BAP entanglement is needed, but not all tripartite entangled symmetric states can be used to solve the problem.

  8. Attraction Effects in Honorific Agreement in Korean.

    Science.gov (United States)

    Kwon, Nayoung; Sturt, Patrick

    2016-01-01

    Previous studies have suggested that sentence processing is mediated by content-addressable direct retrieval processes (McElree, 2000; McElree et al., 2003). However, the memory retrieval processes may differ as a function of the type of dependency. For example, while many studies have reported facilitatory intrusion effects associated with a structurally illicit antecedent during the processing of subject-verb number or person agreement and negative polarity items (Pearlmutter et al., 1999; Xiang et al., 2009; Dillon et al., 2013), studies investigating reflexives have not found consistent evidence of intrusion effects (Parker et al., 2015; Sturt and Kwon, 2015; cf. Nicol and Swinney, 1989; Sturt, 2003). Similarly, the memory retrieval processes could be also sensitive to cross-linguistic differences (cf. Lago et al., 2015). We report one self-paced reading experiment and one eye-tracking experiment that examine the processing of subject-verb honorific agreement, a dependency that is different from those that have been studied to date, in Korean, a typologically different language from those previously studied. The overall results suggest that the retrieval processes underlying the processing of subject-verb honorific agreement in Korean are susceptible to facilitatory intrusion effects from a structurally illicit but feature-matching subject, with a pattern that is similar to subject-verb agreement in English. In addition, the attraction effect was not limited to the ungrammatical sentences but was also found in grammatical sentences. The clear attraction effect in the grammatical sentences suggest that the attraction effect does not solely arise as the result of an error-driven process (cf. Wagers et al., 2009), but is likely also to result from general mechanisms of retrieval processes of activating of potential items in memory (Vasishth et al., 2008).

  9. Attraction Effects in Honorific Agreement in Korean

    Science.gov (United States)

    Kwon, Nayoung; Sturt, Patrick

    2016-01-01

    Previous studies have suggested that sentence processing is mediated by content-addressable direct retrieval processes (McElree, 2000; McElree et al., 2003). However, the memory retrieval processes may differ as a function of the type of dependency. For example, while many studies have reported facilitatory intrusion effects associated with a structurally illicit antecedent during the processing of subject-verb number or person agreement and negative polarity items (Pearlmutter et al., 1999; Xiang et al., 2009; Dillon et al., 2013), studies investigating reflexives have not found consistent evidence of intrusion effects (Parker et al., 2015; Sturt and Kwon, 2015; cf. Nicol and Swinney, 1989; Sturt, 2003). Similarly, the memory retrieval processes could be also sensitive to cross-linguistic differences (cf. Lago et al., 2015). We report one self-paced reading experiment and one eye-tracking experiment that examine the processing of subject-verb honorific agreement, a dependency that is different from those that have been studied to date, in Korean, a typologically different language from those previously studied. The overall results suggest that the retrieval processes underlying the processing of subject-verb honorific agreement in Korean are susceptible to facilitatory intrusion effects from a structurally illicit but feature-matching subject, with a pattern that is similar to subject-verb agreement in English. In addition, the attraction effect was not limited to the ungrammatical sentences but was also found in grammatical sentences. The clear attraction effect in the grammatical sentences suggest that the attraction effect does not solely arise as the result of an error-driven process (cf. Wagers et al., 2009), but is likely also to result from general mechanisms of retrieval processes of activating of potential items in memory (Vasishth et al., 2008). PMID:27630594

  10. Sinopec and COSCO Sign Strategic Partnership Agreement

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Sinopec and China Ocean Shipping (Group)Company (COSCO), the country's biggest shipping company, signed a framework cooperation agreement on June 18 in Beijing, under which COSCO would provide quality crude oil transport from the current 1.94 million deadweight tons. The ambitious plan was made to chter to COSCO's establishment of a long-term strategic partnership for cooperation with Sinopec, China's leading producer and supplier of petroleum products.

  11. 76 FR 4393 - Discover Financial Services Negotiated Service Agreement

    Science.gov (United States)

    2011-01-25

    ... Discover Financial Services Negotiated Service Agreement AGENCY: Postal Regulatory Commission. ACTION... Financial Services negotiated service agreement to the market dominant product list. This notice addresses... 3020, et seq., to add a Discover Financial Services (DFS) negotiated service agreement to the...

  12. Gravity, Bilateral Agreements, and Trade Diversion in the Americas

    OpenAIRE

    Raymond Robertson; Antoni Estevadeordal

    2009-01-01

    Krishna (1998) shows that a bilateral agreement between two countries render a multilateral agreement less attractive if the bilateral agreement is trade diverting. This paper combines Krishna’s model with the empirical approach of Anderson and va

  13. International trade agreements: hazards to health?

    Science.gov (United States)

    Shaffer, Ellen R; Brenner, Joseph E

    2004-01-01

    Since the 1980s, neoliberal policies have prescribed reducing the role of governments, relying on market forces to organize and provide health care and other vital human services. In this context, international trade agreements increasingly serve as mechanisms to enforce the privatization, deregulation, and decentralization of health care and other services, with important implications for democracy as well as for health. Critics contend that social austerity and "free" trade agreements contribute to the rise in global poverty and economic inequality and instability, and therefore to increased preventable illness and death. Under new agreements through the World Trade Organization that cover vital human services such as health care, water, education, and energy, unaccountable, secret trade tribunals could overrule decisions by democratically elected officials on public financing for national health care systems, licensing and training standards for health professionals, patient safety and quality regulations, occupational safety and health, control of hazardous substances such as tobacco and alcohol, the environment, and affordable access to safe water and sanitation. International negotiations in 2003 in Cancun and in Miami suggested that countervailing views are developing momentum. A concerned health care community has begun to call for a moratorium on trade negotiations on health care and water, and to reinvigorate an alternative vision of universal access to vital services.

  14. Jam-X: Wireless Agreement under Interference

    CERN Document Server

    Boano, Carlo Alberto; Zúñiga, Marco Antonio; Voigt, Thiemo

    2012-01-01

    Wireless low-power transceivers used in sensor networks such as IEEE 802.15.4 typically operate in unlicensed frequency bands that are subject to external interference from devices transmitting at much higher power. Communication protocols should therefore be designed to be robust against such interference. A critical building block of many protocols at all layers is agreement on a piece of information among a set of nodes. At the MAC layer, nodes may need to agree on a new time slot or frequency channel; at the application layer nodes may need to agree on handing over a leader role from one node to another. Message loss caused by interference may break agreement in two different ways: none of the nodes use the new information (time slot, channel, leader) and stick with the previous assignment, or - even worse - some nodes use the new information and some do not. This may lead to reduced performance or failures. In this paper we investigate the problem of agreement under interference and point out the limitat...

  15. Flood Frequency Analysis (FFA) in Spanish catchments

    Science.gov (United States)

    Mateo Lázaro, Jesús; Sánchez Navarro, José Ángel; García Gil, Alejandro; Edo Romero, Vanesa

    2016-07-01

    A frequency analysis of rainfall and flow from the available data and applications in Spain takes place. In the case of streamflow, various methods that can be grouped into two categories are used, (1) the gauged method which consist in the analysis of maximum flow rate annual series, and (2) the hydro-meteorological method which take into account processes with rainfall-runoff transformation models. The results are compared with observed data in historical series. Finally, six episodes with actual rainfall and flow record are analyzed. These episodes are also classified according to their frequency domain and results obtained from models are contrasted. To make this work we have used two applications launched in the University of Zaragoza: the SHEE program, which provides a simple and flexible working environment which allows the simultaneous management of the most actual and important databases from a hydrological point of view, highlighting the digital terrain models, the rainfall coverage and the curve number coverage, and that is suitable for the application of hydro-meteorological models; and the EHVE software, which is a hydrological statistical program for analysis of time series of extreme values, suitable for application in models of gauged data.

  16. Enforcing ‘Self-Enforcing’ International Environmental Agreements

    OpenAIRE

    McEvoy, David M.; John K. Stranlund

    2006-01-01

    Theoretical analyses of international environmental agreements (IEAs) have typically employed the concept of self-enforcing agreements to predict the number of parties to such an agreement. The term self-enforcing, however, is a bit misleading. The concept refers to the stability of cooperative agreements, not to enforcing these agreements once they are in place. Most analyses of IEAs simply ignore the issue of enforcing compliance by parties to the terms of an agreement. In this paper we ana...

  17. 44 CFR 206.44 - FEMA-State Agreements.

    Science.gov (United States)

    2010-10-01

    ... Agreement imposes binding obligations on FEMA, States, their local governments, and private nonprofit... Households Program. (b) Terms and conditions. This Agreement describes the incident and the incident...

  18. 42 CFR 442.30 - Agreement as evidence of certification.

    Science.gov (United States)

    2010-10-01

    ... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS STANDARDS FOR PAYMENT TO NURSING FACILITIES AND... preparation and administration of drugs for a sample of residents; (v) Evaluation of a facility's...

  19. Agreement processing and attraction errors in aging: evidence from subject-verb agreement in German.

    Science.gov (United States)

    Reifegerste, Jana; Hauer, Franziska; Felser, Claudia

    2016-11-07

    Effects of aging on lexical processing are well attested, but the picture is less clear for grammatical processing. Where age differences emerge, these are usually ascribed to working-memory (WM) decline. Previous studies on the influence of WM on agreement computation have yielded inconclusive results, and work on aging and subject-verb agreement processing is lacking. In two experiments (Experiment 1: timed grammaticality judgment, Experiment 2: self-paced reading + WM test), we investigated older (OA) and younger (YA) adults' susceptibility to agreement attraction errors. We found longer reading latencies and judgment reaction times (RTs) for OAs. Further, OAs, particularly those with low WM scores, were more accepting of sentences with attraction errors than YAs. OAs showed longer reading latencies for ungrammatical sentences, again modulated by WM, than YAs. Our results indicate that OAs have greater difficulty blocking intervening nouns from interfering with the computation of agreement dependencies. WM can modulate this effect.

  20. Essays on the Economics of Trade Agreements.:Essays on the Economics of Trade Agreements.

    OpenAIRE

    Soete, Sophie

    2017-01-01

    Economic Integration Agreements (EIAs) have been gaining importance in the last two decades in terms of number of countries concluding them, trade flows covered, trade barriers removed and policy domains covered. This dissertation wants to add to the understanding of how these agreements are negotiated and what impact they have, as this is important for academics as well as policymakers and well-informed citizens. In the first two essays of this dissertation, I study the effects of EIAs be...

  1. METC Combustion Research Facility

    Energy Technology Data Exchange (ETDEWEB)

    Halow, J.S.; Maloney, D.J.; Richards, G.A.

    1993-11-01

    The objective of the Morgantown Energy Technology Center (METC) high pressure combustion facility is to provide a mid-scale facility for combustion and cleanup research to support DOE`s advanced gas turbine, pressurized, fluidized-bed combustion, and hot gas cleanup programs. The facility is intended to fill a gap between lab scale facilities typical of universities and large scale combustion/turbine test facilities typical of turbine manufacturers. The facility is now available to industry and university partners through cooperative programs with METC. High pressure combustion research is also important to other DOE programs. Integrated gasification combined cycle (IGCC) systems and second-generation, pressurized, fluidized-bed combustion (PFBC) systems use gas turbines/electric generators as primary power generators. The turbine combustors play an important role in achieving high efficiency and low emissions in these novel systems. These systems use a coal-derived fuel gas as fuel for the turbine combustor. The METC facility is designed to support coal fuel gas-fired combustors as well as the natural gas fired combustor used in the advanced turbine program.

  2. DUPIC facility engineering

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. S.; Choi, J. W.; Go, W. I.; Kim, H. D.; Song, K. C.; Jeong, I. H.; Park, H. S.; Im, C. S.; Lee, H. M.; Moon, K. H.; Hong, K. P.; Lee, K. S.; Suh, K. S.; Kim, E. K.; Min, D. K.; Lee, J. C.; Chun, Y. B.; Paik, S. Y.; Lee, E. P.; Yoo, G. S.; Kim, Y. S.; Park, J. C.

    1997-09-01

    In the early stage of the project, a comprehensive survey was conducted to identify the feasibility of using available facilities and of interface between those facilities. It was found out that the shielded cell M6 interface between those facilities. It was found out that the shielded cell M6 of IMEF could be used for the main process experiments of DUPIC fuel fabrication in regard to space adequacy, material flow, equipment layout, etc. Based on such examination, a suitable adapter system for material transfer around the M6 cell was engineered. Regarding the PIEF facility, where spent PWR fuel assemblies are stored in an annex pool, disassembly devices in the pool are retrofitted and spent fuel rod cutting and shipping system to the IMEF are designed and built. For acquisition of casks for radioactive material transport between the facilities, some adaptive refurbishment was applied to the available cask (Padirac) based on extensive analysis on safety requirements. A mockup test facility was newly acquired for remote test of DUPIC fuel fabrication process equipment prior to installation in the M6 cell of the IMEF facility. (author). 157 refs., 57 tabs., 65 figs.

  3. Wind Energy Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Laurie, Carol

    2017-02-01

    This book takes readers inside the places where daily discoveries shape the next generation of wind power systems. Energy Department laboratory facilities span the United States and offer wind research capabilities to meet industry needs. The facilities described in this book make it possible for industry players to increase reliability, improve efficiency, and reduce the cost of wind energy -- one discovery at a time. Whether you require blade testing or resource characterization, grid integration or high-performance computing, Department of Energy laboratory facilities offer a variety of capabilities to meet your wind research needs.

  4. Sustainable Facilities Management

    DEFF Research Database (Denmark)

    Nielsen, Susanne Balslev; Elle, Morten; Hoffmann, Birgitte

    2004-01-01

    The Danish public housing sector has more than 20 years of experience with sustainable facilities management based on user involvement. The paper outlines this development in a historical perspective and gives an analysis of different approaches to sustainable facilities management. The focus...... is on the housing departments and strateies for the management of the use of resources. The research methods used are case studies based on interviews in addition to literature studies. The paper explores lessons to be learned about sustainable facilities management in general, and points to a need for new...

  5. Wind Energy Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Office of Energy Efficiency and Renewable Energy

    2017-02-01

    This book takes readers inside the places where daily discoveries shape the next generation of wind power systems. Energy Department laboratory facilities span the United States and offer wind research capabilities to meet industry needs. The facilities described in this book make it possible for industry players to increase reliability, improve efficiency, and reduce the cost of wind energy -- one discovery at a time. Whether you require blade testing or resource characterization, grid integration or high-performance computing, Department of Energy laboratory facilities offer a variety of capabilities to meet your wind research needs.

  6. Battelle Primate Facility.

    Science.gov (United States)

    Weller, R E; Wierman, E L; Málaga, C A; Baer, J F; LeMieux, T P

    1991-05-01

    The Battelle Primate Facility houses one of the largest collections of neotropical primates in the United States. The facility is a research resource for undergraduate and graduate students. Battelle staff, as well as staff and faculty from U.S. and international institutions. Researchers have access to the animals for a variety of studies encompassing several disciplines, a large collection of preserved tissues, and an extensive biomedical database. The facility is a World Health Organization Collaborative Center for Clinical Pathology of Neotropical Primates and is involved with the Peruvian Primatological Project in Iquitos, Peru, which provides opportunities for research in primatology and conservation.

  7. AGREEMENT BETWEEN CERN AND UBS SA

    CERN Multimedia

    2002-01-01

    We wish to inform you that the agreement between CERN and UBS SA has been renewed for a period of five years with effect from 1st July 2002. This represents the culmination of work carried out since 1999 by a group consisting of representatives of the Finance Division, the SPL Division, the Staff Association and the Users Office. After analysis of the results of a market survey, it emerged that OVERALL the UBS offered the best conditions and guarantees for the CERN personnel. Owing to developments in the banking market, new conditions have had to be negotiated, which will be presented to you by the UBS (see article).

  8. Inter-rater Agreement on Sentence Formality

    CERN Document Server

    Lahiri, Shibamouli

    2011-01-01

    Formality is one of the most important dimensions of writing style variation. In this study we conducted an inter-rater reliability experiment for assessing sentence formality on a five-point Likert scale, and obtained good agreement results as well as different rating distributions for different sentence categories. We also performed a difficulty analysis to identify the bottlenecks of our rating procedure. Our main objective is to design an automatic scoring mechanism for sentence-level formality, and this study is important for that purpose.

  9. Politeness Strategies of the Provisional Agreement Document

    Directory of Open Access Journals (Sweden)

    Mohammad Shehadeh

    2017-02-01

    Full Text Available This work investigates the politeness strategies of the so-called provisional agreement document in Jordanian context. It shows that such a document maintains several politeness strategies that help resolve any tension between the parties involved. It reflects that politeness is not meant only to elevate the communication between people but also it is an important clue in cataloguing this communication when it occurs in situations where the relationship between the two interlocutors is doomed by tragic event such as murder or car accidents.

  10. On the Drafting of Confidentiality Agreements

    DEFF Research Database (Denmark)

    Drewsen, Merete; Lando, Henrik; Cummins, Tim

    2006-01-01

    This is not a theoretical paper but an application of existing law and economic contract theory to the issue of how to draft a specific kind of contract. It is addressed to practitioners and is intended for practical use. It will be part of a Wiki (as in Wikipedia) for contract drafting, which...... IACCM (International Association for Contract and Commercial Management) has initiated. The main theoretical aspect of the article concerns the application of the value maximization principle (the Coase theorem) to the drafting of confidentiality agreements. While the article is not theoretical, its...

  11. The Kyoto Agreement: Trade and Design

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard

    1999-01-01

    The Kyoto Agreement from 1997 allows trade of CO2 emission quotas between the 38 industrialized countries which have committed themselves to an emission ceiling. However, it does not define how this potential trade system should be designed. The intention was to clarify these matters during...... the 1999 conference in Buenos Aires. Nothing was decided at this conference, leaving open the question of how emission trade is supposed to take place. Therefore, this article aims to propose a design which is both politically and administratively feasible. It may, as such, catch the interest of both...

  12. USDOE/EPRI BIOMASS COFIRING COOPERATIVE AGREEMENT

    Energy Technology Data Exchange (ETDEWEB)

    E. Hughes; D. Tillman

    2000-10-01

    During the period of July 1, 2000 through September 30, 2000, alternatives for relocating the Seward Generating Station cofiring project were investigated. Allegheny Energy Supply Company LLC will accept the separate injection demonstration at its Albright Generating Station. During this period, also, efforts were made at program outreach. Papers were given at the Pittsburgh Coal Conference. This report summarizes the activities during the second calendar quarter in 2000 of the USDOE/EPRI Biomass Cofiring Cooperative Agreement. It focuses upon reporting the results of the relocation of Seward, and on the outreach efforts.

  13. 75 FR 19168 - Federal Acquisition Regulation; FAR Case 2009-005, Use of Project Labor Agreements for Federal...

    Science.gov (United States)

    2010-04-13

    ... connection with building such high profile facilities as the trans-Alaska pipeline and Disney World. GAO... agreement, as they may decide appropriate, on large-scale construction projects, where the total cost to the... predict labor costs when bidding on contracts and to ensure a steady supply of labor on contracts...

  14. National Solar Thermal Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The National Solar Thermal Test Facility (NSTTF) is the only test facility in the United States of its type. This unique facility provides experimental engineering...

  15. Skilled nursing or rehabilitation facilities

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000435.htm Skilled nursing or rehabilitation facilities To use the sharing features ... facility. Who Needs to go to a Skilled Nursing or Rehabilitation Facility? Your health care provider may ...

  16. National Solar Thermal Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The National Solar Thermal Test Facility (NSTTF) is the only test facility in the United States of its type. This unique facility provides experimental engineering...

  17. Hydrography - Water Pollution Control Facilities

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — A Water Pollution Control Facility is a DEP primary facility type related to the Water Pollution Control Program. The sub-facility types related to Water Pollution...

  18. Wind Tunnel Testing Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — NASA Ames Research Center is pleased to offer the services of our premier wind tunnel facilities that have a broad range of proven testing capabilities to customers...

  19. Coastal Inlet Model Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Coastal Inlet Model Facility, as part of the Coastal Inlets Research Program (CIRP), is an idealized inlet dedicated to the study of coastal inlets and equipped...

  20. The Birmingham Irradiation Facility

    Science.gov (United States)

    Dervan, P.; French, R.; Hodgson, P.; Marin-Reyes, H.; Wilson, J.

    2013-12-01

    At the end of 2012 the proton irradiation facility at the CERN PS [1] will shut down for two years. With this in mind, we have been developing a new ATLAS scanning facility at the University of Birmingham Medical Physics cyclotron. With proton beams of energy approximately 30 MeV, fluences corresponding to those of the upgraded Large Hadron Collider (HL-LHC) can be reached conveniently. The facility can be used to irradiate silicon sensors, optical components and mechanical structures (e.g. carbon fibre sandwiches) for the LHC upgrade programme. Irradiations of silicon sensors can be carried out in a temperature controlled cold box that can be scanned through the beam. The facility is described in detail along with the first tests carried out with mini (1×1 cm2) silicon sensors.

  1. Hypersonic Tunnel Facility (HTF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Hypersonic Tunnel Facility (HTF) is a blow-down, non-vitiated (clean air) free-jet wind tunnel capable of testing large-scale, propulsion systems at Mach 5, 6,...

  2. A cryogenic test facility

    Science.gov (United States)

    Veenendaal, Ian

    The next generation, space-borne instruments for far infrared spectroscopy will utilize large diameter, cryogenically cooled telescopes in order to achieve unprecedented sensitivities. Low background, ground-based cryogenic facilities are required for the cryogenic testing of materials, components and subsystems. The Test Facility Cryostat (TFC) at the University of Lethbridge is a large volume, closed cycle, 4K cryogenic facility, developed for this purpose. This thesis discusses the design and performance of the facility and associated external instrumentation. An apparatus for measuring the thermal properties of materials is presented, and measurements of the thermal expansion and conductivity of carbon fibre reinforced polymers (CFRPs) at cryogenic temperatures are reported. Finally, I discuss the progress towards the design and fabrication of a demonstrator cryogenic, far infrared Fourier transform spectrometer.

  3. Treated Effluent Disposal Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Treated non-hazardous and non-radioactive liquid wastes are collected and then disposed of through the systems at the Treated Effluent Disposal Facility (TEDF). More...

  4. Aviation Flight Support Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility consists of a 75' x 200' hanger with two adjacent helicopter pads located at Felker Army Airfield on Fort Eustis. A staff of Government and contractor...

  5. Space Power Facility (SPF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Space Power Facility (SPF) houses the world's largest space environment simulation chamber, measuring 100 ft. in diameter by 122 ft. high. In this chamber, large...

  6. GPS Satellite Simulation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The GPS satellite simulation facility consists of a GPS satellite simulator controlled by either a Silicon Graphics Origin 2000 or PC depending upon unit under test...

  7. Robotics Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This 60 feet x 100 feet structure on the grounds of the Fort Indiantown Gap Pennsylvania National Guard (PNG) Base is a mixed-use facility comprising office space,...

  8. Airborne Evaluation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — AFRL's Airborne Evaluation Facility (AEF) utilizes Air Force Aero Club resources to conduct test and evaluation of a variety of equipment and concepts. Twin engine...

  9. Geophysical Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Geophysical Research Facility (GRF) is a 60 ft long × 22 ft wide × 7 ft deep concrete basin at CRREL for fresh or saltwater investigations and can be temperature...

  10. Climatic Environmental Test Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — RTTC has an extensive suite of facilities for supporting MIL-STD-810 testing, toinclude: Temperature/Altitude, Rapid Decompression, Low/High Temperature,Temperature...

  11. IHS Facility Locator

    Data.gov (United States)

    U.S. Department of Health & Human Services — This map can be used to find an Indian Health Service, Tribal or Urban Indian Health Program facility. This map can be used to: Zoom in to a general location to...

  12. Environmental Test Facility (ETF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Test Facility (ETF) provides non-isolated shock testing for stand-alone equipment and full size cabinets under MIL-S-901D specifications. The ETF...

  13. Air Data Calibration Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility is for low altitude subsonic altimeter system calibrations of air vehicles. Mission is a direct support of the AFFTC mission. Postflight data merge is...

  14. Mass Properties Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility is used to acquire accurate weight, 3 axis center of gravity and 3 axis moment of inertia measurements for air launched munitions and armament equipment.

  15. Airborne & Field Sensors Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — RTTC facilities include an 800' x 60' paved UAV operational area, clearapproach/departure zone, concrete pads furnished with 208VAC, 3 phase,200 amp power, 20,000 sq...

  16. Frost Effects Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Full-scale study in controlled conditionsThe Frost Effects Research Facility (FERF) is the largest refrigerated warehouse in the United States that can be used for a...

  17. Concrete Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This is a 20,000-sq ft laboratory that supports research on all aspects of concrete and materials technology. The staff of this facility offer wide-ranging expertise...

  18. Water Tunnel Facility

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s High-Pressure Water Tunnel Facility in Pittsburgh, PA, re-creates the conditions found 3,000 meters beneath the ocean’s surface, allowing scientists to study...

  19. Structural Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides a wide variety of testing equipment, fixtures and facilities to perform both unique aviation component testing as well as common types of materials testing...

  20. Structural Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides a wide variety of testing equipment, fixtures and facilities to perform both unique aviation component testing as well as common types of materials testing...

  1. Robotics Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This 60 feet x 100 feet structure on the grounds of the Fort Indiantown Gap Pennsylvania National Guard (PNG) Base is a mixed-use facility comprising office space,...

  2. Wind Tunnel Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This ARDEC facility consists of subsonic, transonic, and supersonic wind tunnels to acquire aerodynamic data. Full-scale and sub-scale models of munitions are fitted...

  3. Pittsburgh City Facilities

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Pittsburgh City FacilitiesIncludes: City Administrative Buildings, Police Stations, Fire Stations, EMS Stations, DPW Sites, Senior Centers, Recreation Centers, Pool...

  4. Dialysis Facility Compare Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — These are the official datasets used on the Medicare.gov Dialysis Facility Compare Website provided by the Centers for Medicare and Medicaid Services. These data...

  5. Pittsburgh City Facilities

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Pittsburgh City FacilitiesIncludes: City Administrative Buildings, Police Stations, Fire Stations, EMS Stations, DPW Sites, Senior Centers, Recreation Centers,...

  6. Advanced Microscopy Facility

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides a facility for high-resolution studies of complex biomolecular systems. The goal is an understanding of how to engineer biomolecules for various...

  7. VT Telecommunication Facilities

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The UtilityTelecom_TELEFAC data layer contains points which are intended to represent the location of telecommunications facilities (towers and/or...

  8. Waste Water Facilities

    Data.gov (United States)

    Vermont Center for Geographic Information — This dataset contains the locations of municipal and industrial direct discharge wastewater treatment facilities throughout the state of Vermont. Spatial data is not...

  9. FDA Certified Mammography Facilities

    Science.gov (United States)

    ... Products Radiation-Emitting Products Home Radiation-Emitting Products Mammography Quality Standards Act and Program Consumer Information (MQSA) ... it Email Print This list of FDA Certified Mammography Facilities is updated weekly. If you click on ...

  10. Mark 1 Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

  11. The Birmingham Irradiation Facility

    CERN Document Server

    Dervan, P; Hodgson, P; Marin-Reyes, H; Wilson, J

    2013-01-01

    At the end of 2012 the proton irradiation facility at the CERN PS [1] will shut down for two years. With this in mind, we have been developing a new ATLAS scanning facility at the University of Birmingham Medical Physics cyclotron. With proton beams of energy approximately 30 MeV, fluences corresponding to those of the upgraded Large Hadron Collider (HL-LHC) can be reached conveniently. The facility can be used to irradiate silicon sensors, optical components and mechanical structures (e.g. carbon fibre sandwiches) for the LHC upgrade programme. Irradiations of silicon sensors can be carried out in a temperature controlled cold box that can be scanned through the beam. The facility is described in detail along with the first tests carried out with mini (1 x 1 cm^2 ) silicon sensors.

  12. Liquid Effluent Retention Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Liquid Effluent Retention Facility (LERF) is located in the central part of the Hanford Site. LERF is permitted by the State of Washington and has three liquid...

  13. TNO HVAC facilities

    NARCIS (Netherlands)

    Hammink, H.A.J.

    2015-01-01

    TNO has extensive knowledge of heating, ventilation and air conditioning (HVAC), and can offer its services through theoretical studies, laboratory experiments and field measurements. This complete scope, made possible through our test facilities, enables the effective development of new products,

  14. Ballistic Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Ballistic Test Facility is comprised of two outdoor and one indoor test ranges, which are all instrumented for data acquisition and analysis. Full-size aircraft...

  15. Advanced Microanalysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Microanalysis Facility fully integrates capabilities for chemical and structural analysis of electronic materials and devices for the U.S. Army and DoD....

  16. Coastal Harbors Modeling Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Coastal Harbors Modeling Facility is used to aid in the planning of harbor development and in the design and layout of breakwaters, absorbers, etc.. The goal is...

  17. Corrosion Testing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Corrosion Testing Facility is part of the Army Corrosion Office (ACO). It is a fully functional atmospheric exposure site, called the Corrosion Instrumented Test...

  18. Joint Computing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Raised Floor Computer Space for High Performance ComputingThe ERDC Information Technology Laboratory (ITL) provides a robust system of IT facilities to develop and...

  19. Skilled Nursing Facility PPS

    Data.gov (United States)

    U.S. Department of Health & Human Services — Section 4432(a) of the Balanced Budget Act (BBA) of 1997 modified how payment is made for Medicare skilled nursing facility (SNF) services. Effective with cost...

  20. Frost Effects Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Full-scale study in controlled conditions The Frost Effects Research Facility (FERF) is the largest refrigerated warehouse in the United States that can be used for...

  1. Electra Laser Facility

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: The Electra Laser Facility is used to develop the science and technology needed to develop a reliable, efficient, high-energy, repetitively pulsed krypton...

  2. Hypersonic Tunnel Facility (HTF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Hypersonic Tunnel Facility (HTF) is a blow-down, non-vitiated (clean air) free-jet wind tunnel capable of testing large-scale, propulsion systems at Mach 5, 6,...

  3. Pit Fragment Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility contains two large (20 foot high by 20 foot diameter) double walled steel tubs in which experimental munitions are exploded while covered with sawdust....

  4. Powder Metallurgy Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The facility is uniquely equipped as the only laboratory within DA to conduct PM processing of refractory metals and alloys as well as the processing of a wide range...

  5. Field Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Field Research Facility (FRF) located in Duck, N.C. was established in 1977 to support the U.S. Army Corps of Engineers' coastal engineering mission. The FRF is...

  6. Advanced Microanalysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Microanalysis Facility fully integrates capabilities for chemical and structural analysis of electronic materials and devices for the U.S. Army and DoD....

  7. Laser Guidance Analysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility, which provides for real time, closed loop evaluation of semi-active laser guidance hardware, has and continues to be instrumental in the development...

  8. Combustion Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — For more than 30 years The Combustion Research Facility (CRF) has served as a national and international leader in combustion science and technology. The need for a...

  9. Agreement between radiographic and photographic trabecular patterns

    Energy Technology Data Exchange (ETDEWEB)

    Korstjens, C.M.; Geraets, W.G.M.; Stelt, P.F. van der [Dept. of Oral Radiology, Academic Centre for Dentistry, Amsterdam (Netherlands); Spruijt, R.J. [Div. of Psychosocial Research and Epidemiology, Netherlands Cancer Inst., Amsterdam (Netherlands); Mosekilde, L. [Dept. of Cell Biology, Univ. of Aarhus (Denmark)

    1998-11-01

    Purpose: It has been hypothesized that photographs can facilitate the interpretation of the radiographic characteristics of trabecular bone. The reliability of these photographic and radiographic approaches has been determined, as have various agreements between the two approaches and their correlations with biomechanical characteristics. Material and Methods: Fourteen vertebral bodies were obtained at autopsy from 6 women and 8 men aged 22-76 years. Photographs (n=28) and radiographs (n=28) were taken of midsagittal slices from the third lumbar vertebra. The radiographs and photographs were digitized and the geometric properties of the trabecular architecture were then determined with a digital images analysis technique. Information on the compressive strength and ash density of the vertebral body was also available. Results: The geometric properties of both radiographs and photographs could be measured with a high degree of reliability (Cronbach`s {alpha}>0.85). Agreement between the radiographic and photographic approaches was mediocre as only the radiographic measurements showed insignificant correlations (p<0.05) with the biomechanical characteristics. We suggest that optical phenomena may result in the significant correlations between the photographs and the biomechanical characteristics. Conclusion: For digital image processing, radiography offers a superior description of the architecture of trabecular bone to that offered by photography. (orig.)

  10. Neural Network Solution For Service Level Agreement

    Directory of Open Access Journals (Sweden)

    Sarmad Al-Aloussi

    2013-03-01

    Full Text Available Service Oriented Computing is playing an important role in sharing the industry and the way business is conducted and services are delivered and managed. This paradigm is expected to have major impact on service economy; the service sector includes health services, financial services, government services, etc. This involves significant interaction between clients and service providers[1]. This paper is pointed in addressing the problem of enabling Service Level Agreement (SLA oriented resources allocation in data centers to satisfy competing applications demand for computing services. A QoS report designed to compare performance variables to QoS parameters and indicate when a threshold has been crossed. This paper was suggested a methodology which helps in SLA evaluation and comparison. The methodology was found on the adoption of policies both for service behavior and SLA description and on the definition of a metric function for evaluation and comparison of policies. In addition, this paper contributes a new philosophy to evaluate the agreements between user and service provider by monitoring the measurable and immeasurable qualities to extract the decision by using artificial neural networks (ANN.

  11. Calibration Facilities for NIF

    Energy Technology Data Exchange (ETDEWEB)

    Perry, T.S.

    2000-06-15

    The calibration facilities will be dynamic and will change to meet the needs of experiments. Small sources, such as the Manson Source should be available to everyone at any time. Carrying out experiments at Omega is providing ample opportunity for practice in pre-shot preparation. Hopefully, the needs that are demonstrated in these experiments will assure the development of (or keep in service) facilities at each of the laboratories that will be essential for in-house preparation for experiments at NIF.

  12. Facilities | ECHO | US EPA

    Science.gov (United States)

    ECHO, Enforcement and Compliance History Online, provides compliance and enforcement information for approximately 800,000 EPA-regulated facilities nationwide. ECHO includes permit, inspection, violation, enforcement action, and penalty information about facilities regulated under the Clean Air Act (CAA) Stationary Source Program, Clean Water Act (CWA) National Pollutant Elimination Discharge System (NPDES), and/or Resource Conservation and Recovery Act (RCRA). Information also is provided on surrounding demographics when available.

  13. Auditing radiation sterilization facilities

    Science.gov (United States)

    Beck, Jeffrey A.

    The diversity of radiation sterilization systems available today places renewed emphasis on the need for thorough Quality Assurance audits of these facilities. Evaluating compliance with Good Manufacturing Practices is an obvious requirement, but an effective audit must also evaluate installation and performance qualification programs (validation_, and process control and monitoring procedures in detail. The present paper describes general standards that radiation sterilization operations should meet in each of these key areas, and provides basic guidance for conducting QA audits of these facilities.

  14. 22 CFR 120.22 - Technical assistance agreement.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Technical assistance agreement. 120.22 Section... DEFINITIONS § 120.22 Technical assistance agreement. An agreement (e.g., contract) for the performance of a defense service(s) or the disclosure of technical data, as opposed to an agreement granting a right or...

  15. 78 FR 32356 - United States-Korea Free Trade Agreement

    Science.gov (United States)

    2013-05-30

    ... 178 RIN 1515-AD86 United States-Korea Free Trade Agreement AGENCIES: U.S. Customs and Border... United States-Korea Free Trade Agreement entered into by the United States and the Republic of Korea... ``Korea'') signed the United States-Korea Free Trade Agreement (hereinafter ``UKFTA'' or the ``Agreement...

  16. 76 FR 65365 - United States-OMAN Free Trade Agreement

    Science.gov (United States)

    2011-10-21

    ... 178 RIN 1515-AD68 United States-OMAN Free Trade Agreement AGENCIES: U.S. Customs and Border Protection... ``Parties'') entered into the U.S.-Oman Free Trade Agreement (``OFTA'' or ``Agreement''). The provisions of... have more free trade agreements like the OFTA. Conclusion Accordingly, CBP believes that the interim...

  17. 76 FR 697 - United States-Oman Free Trade Agreement

    Science.gov (United States)

    2011-01-06

    ... States--Oman Free Trade Agreement AGENCY: U.S. Customs and Border Protection, Department of Homeland... Free Trade Agreement entered into by the United States and the Sultanate of Oman. DATES: Interim rule...'') entered into the U.S.--Oman Free Trade Agreement (``OFTA'' or ``Agreement''). The stated objectives of the...

  18. 24 CFR 266.15 - Risk-Sharing Agreement.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Risk-Sharing Agreement. 266.15... Provisions § 266.15 Risk-Sharing Agreement. Execution of a Risk-Sharing Agreement is a prerequisite to participation in this program. The Risk-Sharing Agreement shall be in a form acceptable to the Commissioner. ...

  19. 32 CFR 21.680 - Technology investment agreements.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Technology investment agreements. 21.680 Section... AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Definitions § 21.680 Technology investment... of the nation's technology and industrial base. Technology investment agreements include one kind...

  20. 32 CFR 37.1375 - Technology investment agreements.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Technology investment agreements. 37.1375... AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1375 Technology investment agreements. A special class of assistance instruments used to increase involvement...