WorldWideScience

Sample records for facilities egress windows

  1. Photometric Evaluation of Photo-luminescent Materials for Multi-Egress Guidance Placards: Lighting Environment Test Facility

    Science.gov (United States)

    Maida, James C.

    2005-01-01

    The purpose of this investigation was to evaluate several photo luminescent (PL) materials being considered for construction of emergency egress placards in the International Space Station (ISS). The use of PL material is intended to allow the placards to be read by ISS crew members in the event of an extensive power failure resulting in the loss of interior illumination.

  2. Windows

    DEFF Research Database (Denmark)

    Heiselberg, Per; Svidt, Kjeld; Nielsen, Peter V.

    In natural ventilation systems fresh air is often provided through opening of windows. However, the knowledge of the performance of windows is rather limited. Computation of natural ventilation air flow through windows is most commonly made using discharge coefficients, that are regarded as being...... constant. The reported results show that the discharge coefficient for a window opening cannot be regarded as a constant and that it varies considerably with the size of the opening area, the window type and the temperature difference. Therefore, the use of a constant value can lead to serious errors...

  3. A method for comparison testing of window accessories: The AMSCO thermal test facility

    Energy Technology Data Exchange (ETDEWEB)

    Lexen, T.C.; Muldary, P.F.

    1985-01-01

    A test facility has been developed for the comparison of the thermal performance of window accessories. The facility is presented as a developmental tool, allowing direct comparison testing of prototypes and new products, under controlled interior and real weather conditions. Nighttime U-value testing is emphasized; testing options and limitations are discussed, along with future plans.

  4. Utilizing the US Lab Nadir Research Window for Remote Sensing Operations with The Window Observational Research Facility (WORF)

    Science.gov (United States)

    Turner, Richard; Barley, Bryan; Gilbert, Paul A. (Technical Monitor)

    2002-01-01

    The Window Observational Research Facility (WORF) is an ISPR-based rack facility designed to take advantage of the high optical quality US Lab Nadir research window. The WORF is based on the ISS Expedite the Processing of Experiments to Space Station (EXPRESS) rack mechanical structure and electronic systems. The WORF has a unique payload volume located at the center of the rack that provides access to the window. The interior dimensions of the payload volume are 34-in. (86.36 cm) wide by 33-in. (83.82 cm) high by 23-in. (58.42 cm) deep. This facility supports the deployment of payloads such as 9 in. aerial photography cameras and 12 in. diameter optical equipment. The WORF coupled with the optical quality of the United States Lab window support the deployment of various payload disciplines. The WORF provides payloads with power, data command and control, air cooling, water cooling, and video processing. The WORF's payload mounting surfaces and interfaces include the interior payload mounting shelf and the interior and exterior aircraft-like seat tracks. The payload mounting shelf is limited to a maximum mass of 136 kg (299 pounds). The WORF can accommodate large payloads such as the commonly used Leica-Heerbrug RC-30 aerial photography camera (whose dimensions are 53.3 cm (21-in.) wide by 50.8 cm (20-in.) deep by 76.2 cm (30-in.) long). The performance characteristics of the WORF allow it to support an array of payload disciplines. The WORF provides a maximum of 3 Kw at 28 Vdc and has a maximum data rate of 10 Mbps. The WORF's unique payload volume is designed to be light-tight, down to 2.8 x 10(exp -11) Watts/cm2/steradian, and have low-reflective surfaces. This specially designed WORF interior supports payload investigations that observe low-light-level phenomenon such as aurora. Although the WORF rack does not employ any active rack isolation (i.e., vibration dampening) technology, the rack provides a very stable environment for payload operations (on the order

  5. The Windows to the Universe Project: A Facility for Inter-American Geoscience Education and Outreach

    Science.gov (United States)

    Johnson, R. M.; Lagrave, M.; Araujo-Pradere, E.; Russell, R.; Gardiner, L.; Bergman, J.; Genyuk, J.; Henderson, S.; Dimarco, M.; Metcalfe, T.

    2005-05-01

    Windows to the Universe (http://www.windows.ucar.edu) is a popular and comprehensive Earth and space science education web site that uses an interdisciplinary approach to engage our global audience. The entire Windows to the Universe site (roughly 7,000 pages) is being translated into Spanish, with support from the National Science Foundation. Large portions have already been "published" to the web and have been in use since October 2003. Web site statistics indicate that use of the Spanish portion of the site has quickly ramped up to ~20% of total site traffic. Approximately 150,000 users per month have accessed the Spanish-language segments of the site over the past academic year, in addition to the visitors to the English version of the website. The largest fraction of non-US users of the Spanish website come from Mexico, with growing use from countries from Central and South America and Spain. A total of 6.7 million users from around the world accessed the educational resources on this comprehensive website in 2004. An exciting new web-based development interface utilizing templates and an image database allows scientists from around the world to collaborate with the Windows to the Universe team, becoming remote developers on the website. This approach has proven to work effectively for scientists eager to efficiently get their science research results out to the public, taking advantage of their specialized expertise and yet not requiring them to become specialists in informal or formal K-12 education.

  6. Method of measuring nighttime U-values using the Mobile Window Thermal Test (MoWiTT) Facility

    Energy Technology Data Exchange (ETDEWEB)

    Klems, J.H.

    1992-04-01

    Although primarily designed for studying the dynamic net energy flows through fenestration systems over the full diurnal cycle, the Mobile Window Thermal Test (MoWiTT) Facility is also frequently used to measure nighttime U-values. These measurements have the advantage of incorporating the exterior film coefficient resulting from the true ambient conditions at a particular time and location, rather than relying on a laboratory simulation of some assumed average or extreme condition. On the other hand, the MoWiTT is a much more complicated facility than a laboratory hot box, and the number of potential error sources is correspondingly larger. The method of deriving the nighttime U-value from directly measured data and the effect of random and systematic errors are discussed.

  7. Environmental Effect on Egress Simulation

    KAUST Repository

    Rodriguez, Samuel

    2012-01-01

    Evacuation and egress simulations can be a useful tool for studying the effect of design decisions on the flow of agent movement. This type of simulation can be used to determine before hand the effect of design decisions and enable exploration of potential improvements. In this work, we study at how agent egress is affected by the environment in real world and large scale virtual environments and investigate metrics to analyze the flow. Our work differs from many evacuation systems in that we support grouping restrictions between agents (e.g., families or other social groups traveling together), and model scenarios with multiple modes of transportation with physically realistic dynamics (e.g., individuals walk from a building to their own cars and leave only when all people in the group arrive).

  8. STS-46 MS Chang-Diaz floats in life raft during water egress training at JSC

    Science.gov (United States)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Mission Specialist (MS) Franklin R. Chang-Diaz, wearing launch and entry suit (LES) and launch and entry helmet (LEH), relies on a one-person life raft to get him to 'safety' during a launch emergency egress (bailout) simulation conducted in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool.

  9. STS-35 Pilot Gardner shoots picture during water egress training at JSC

    Science.gov (United States)

    1990-01-01

    STS-35 Pilot Guy S. Gardner shoots picture using a 35mm camera during water egress training conducted in the Weightless Environment Training Facility (WETF) Bldg 29 at JSC. Gardner is wearing a launch and entry suit and a life jacket.

  10. STS-37 Pilot Kenneth D. Cameron during egress training in JSC's WETF Bldg 29

    Science.gov (United States)

    1990-01-01

    STS-37 Pilot Kenneth D. Cameron, wearing launch and entry suit (LES), discusses simulated emergency egress training on the pool side of JSC's Weightless Environment Training Facility (WETF) Bldg 29. Cameron will be dropped into a simulated ocean, the WETF's 25-ft pool, into which a parachute landing might be made.

  11. STS-46 MS Chang-Diaz floats in life raft during water egress training at JSC

    Science.gov (United States)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Mission Specialist (MS) Franklin R. Chang-Diaz, wearing launch and entry suit (LES) and launch and entry helmet (LEH), relies on a one-person life raft to get him to 'safety' during a launch emergency egress (bailout) simulation conducted in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool.

  12. Modeling Post-Accident Vehicle Egress

    Science.gov (United States)

    2013-01-01

    functionality, only basic clearance issues could be investigated; improvements to the Humosim Framework and Jack software are needed to enable rapid...unique requirements of military applications have challenged the capability of current software . Soldiers are often wearing and carrying a...for military vehicles, ingress and egress are evaluated by acquiring vehicles (when available) or by building expensive mockups and running timed

  13. Measurement of fenestration net energy performance: Considerations leading to development of a Mobile Window Thermal Test (MoWitt) facility

    Energy Technology Data Exchange (ETDEWEB)

    Klems, J.H.

    1988-08-01

    The authors present a detailed consideration of the energy flows entering a building space and the effect of random measurement errors on determining fenestration performance. Estimates of error magnitudes are made for a passive test cell; they show that a more accurate test facility is needed for reliable measurements on fenestration systems with thermal resistance 2-10 times that of single glazing or with shading coefficients less than 0.7. A test facility of this type, built at Lawrence Berkeley Laboratory, is described. The effect of random errors in this facility is discussed and computer calculations of its performance are presented. The discussion shows that, for any measurement facility, random errors are most serious in nighttime measurements, and systematic errors are most important in daytime measurements. It is concluded that, for this facility, errors from both sources should be small.

  14. STS-29 MS Bagian during post landing egress exercises in JSC FFT mockup

    Science.gov (United States)

    1989-01-01

    STS-29 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) James P. Bagian works his way down to 'safety' using a sky-genie device during post landing emergency egress exercises in JSC full fuselage trainer (FFT) located in the Mockup and Integration Laboratory Bldg 9A. Bagian, wearing orange launch and entry suit (LES) and launch and entry helmet (LEH), lowers himself using the sky genie after egressing from crew compartment overhead window W8. Fellow crewmembers and technicians watch Bagian's progress. Standing in navy blue LES is MS Robert C. Springer with MS James F. Buchli seated behind him on his right and Pilot John E. Blaha seated behind him on his left. Bagian is one of several astronauts who has been instrumental in developing the new crew escape system (CES) equipment (including parachute harness).

  15. New Roles for Perforins and Proteases in Apicomplexan Egress

    OpenAIRE

    Roiko, Marijo S.; Carruthers, Vern B.

    2009-01-01

    Egress is a pivotal step in the lifecycle of intracellular pathogens initiating the transition from an expiring host cell to a fresh target cell. While much attention has been focused on understanding cell invasion by intracellular pathogens, recent work is providing a new appreciation of mechanisms and therapeutic potential of microbial egress. This review highlights recent insight into cell egress by apicomplexan parasites and emerging contributions of membranolytic and proteolytic secretor...

  16. Windows Azure

    CERN Document Server

    Johnson, Bruce; Chambers, James; Garber, Danny; Malik, Jamal; Fazio, Adam

    2013-01-01

    A collection of five must-have Azure titles, from some of the biggest names in the field Available individually, but at a discounted rate for the collection, this bundle of five e-books covers key developer and IT topics of Windows Azure, including ASP.NET, mobile services, web sites, data storage, and the hybrid cloud. A host of Microsoft employees and MPVs come together to cover the biggest challenges that professionals face when working with Windows Azure. The e-books included are as follows: Windows Azure and ASP.NET MVC MigrationWindows Azure Mobile ServicesWindows Azure Web SitesWindows

  17. Window Stories

    DEFF Research Database (Denmark)

    Hauge, Bettina

    This research project has investigated 17 households in Germany (cities and rural areas). The main aim was to learn about the significance of the window to these people: What they think of their windows, how, when and why they use them in their everyday life, if they have a favorite window and why...

  18. Astronaut Neil A. Armstrong during water egress training

    Science.gov (United States)

    1965-01-01

    Astronaut Neil A. Armstrong, Gemini 5 backup crew command pilot, sits in the Gemini Static Article 5 spacecraft and prepares to be lowered from the deck of the NASA Motor Vessel Retriever for water egress training in the Gulf.

  19. STS-34 crewmembers sit in M1-13 APC during emergency egress training at KSC

    Science.gov (United States)

    1989-01-01

    STS-34 crewmembers sit in M1-13 Armored Personnel Carrier (APC) during emergency egress training at KSC's shuttle landing facility (SLF) prior to terminal countdown demonstration test (TCDT) activities. Wearing launch and entry suits (LESs), are (from left) Mission Specialist (MS) Ellen S. Baker, MS Shannon W. Lucid, Commander Donald E. Williams (right side, in back), MS Franklin R. Chang-Diaz, and Pilot Michael J. McCulley (holding headset). View provided by KSC with alternate number KSC-89PC-871.

  20. Window shopping

    Energy Technology Data Exchange (ETDEWEB)

    Best, D.

    1990-03-01

    The author addresses the energy efficiency of windows and describes changes and new products available in this consumer information article. Experiments currently being done by Lawrence Berkeley Laboratory (LBL), Bonneville Power Authority and the Washington State Energy Office show that some of these superwindows collect more energy from the sun than they let escape from inside the home. One type of window in current production is the low-E (low-emissivity) and the IGUs (insulated glass units). Low-E techniques include glazing of the glass with various materials including polyester and metallic coatings. Other measures include filling the airspace in double pane windows with argon, aerogel or by creating a vacuum in the airspace. Another factor the author considers is ultraviolet light protection.

  1. Parenthetical Windows

    DEFF Research Database (Denmark)

    Lemi, Esther; Triantafyllidis, Georgios

    2016-01-01

    Parenthetical Window is a project that engages scientific research in human perception providing a platform for users to experience their own limits and needs in their individual circadian rhythm. The presentation focuses on a case study in a community of dancers where the individual needs in light...... these for the construction of a final installation that focuses on the construction of a dark room that provides artificial stimuli through a window with only artificial information. The abstract translation of sound to image through artificial light is a common endeavour in the history of arts and its aesthetics, since...

  2. Efficient egress of escaping ants stressed with temperature.

    Directory of Open Access Journals (Sweden)

    Santiago Boari

    Full Text Available In the present work we investigate the egress times of a group of Argentine ants (Linepithema humile stressed with different heating speeds. We found that the higher the temperature ramp is, the faster ants evacuate showing, in this sense, a group-efficient evacuation strategy. It is important to note that even when the life of ants was in danger, jamming and clogging was not observed near the exit, in accordance with other experiments reported in the literature using citronella as aversive stimuli. Because of this clear difference between ants and humans, we recommend the use of some other animal models for studying competitive egress dynamics as a more accurate approach to understanding competitive egress in human systems.

  3. Efficient Egress of Escaping Ants Stressed with Temperature

    Science.gov (United States)

    Boari, Santiago; Josens, Roxana; Parisi, Daniel R.

    2013-01-01

    In the present work we investigate the egress times of a group of Argentine ants (Linepithema humile) stressed with different heating speeds. We found that the higher the temperature ramp is, the faster ants evacuate showing, in this sense, a group-efficient evacuation strategy. It is important to note that even when the life of ants was in danger, jamming and clogging was not observed near the exit, in accordance with other experiments reported in the literature using citronella as aversive stimuli. Because of this clear difference between ants and humans, we recommend the use of some other animal models for studying competitive egress dynamics as a more accurate approach to understanding competitive egress in human systems. PMID:24312264

  4. Motility precedes egress of malaria parasites from oocysts

    Science.gov (United States)

    Klug, Dennis; Frischknecht, Friedrich

    2017-01-01

    Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito midgut wall and are released into the hemolymph, from where they invade the salivary glands and are subsequently transmitted to the vertebrate host. We found that a thrombospondin-repeat containing sporozoite-specific protein named thrombospondin-releated protein 1 (TRP1) is important for oocyst egress and salivary gland invasion, and hence for the transmission of malaria. We imaged the release of sporozoites from oocysts in situ, which was preceded by active motility. Parasites lacking TRP1 failed to migrate within oocysts and did not egress, suggesting that TRP1 is a vital component of the events that precede intra-oocyst motility and subsequently sporozoite egress and salivary gland invasion. DOI: http://dx.doi.org/10.7554/eLife.19157.001 PMID:28115054

  5. Astronauts Scott Carpenter and Walter Schirra completes water egress test

    Science.gov (United States)

    1962-01-01

    Project Mercury Astronauts M. Scott Carpenter, prime pilot of the Mercury-Atlas 7, prepares to go through a water egress test. Astronaut Walter M. Schirra (back to camera), the backup MA-7 pilot is also present. Carpenter and Schirra are in the Mercury pressure suit, without the helmet. Behind them is an inflated life raft.

  6. Ethanol and isopropanol trigger rapid egress of intracellular Eimeria tenella sporozoites.

    Science.gov (United States)

    Yan, Xinlei; Liu, Xianyong; Ji, Yongsheng; Tao, Geru; Suo, Xun

    2015-02-01

    Egress from host cells is a vital step of the intracellular life cycle of apicomplexan parasites such as Toxoplasma gondii. This phenomenon has attracted attentions from many research groups. Previous studies have shown that ethanol could stimulate the release of microneme proteins by elevating intracellular Ca(2+) concentration of T. gondii, resulting in the parasite egress from host cells. However, little information about egress is known on Eimeria species, the causative agent of coccidiosis in poultry and livestock. In this report, we studied the effect of ethanol and isopropanol on the egress of eimerian parasites. Eimeria tenella sporozoites cultured in primary chicken kidney cells were treated with ethanol and isopropanol, then the egressed parasites were analyzed. Ethanol and isopropanol could induce the rapid egress of E. tenella sporozoites from host cells. No substantial damage was found in parasite-egressed host cells. Compared to the freshly isolated sporozoites, the re-invading ability and reproductivity of the egressed parasites significantly decreased by 43.4 and 44.1 % individually. We also found that fewer sporozoites egressed from host cells when the parasites developed for a longer time before the alcohol treatment. These results demonstrate an in vitro egress mode different from that of T. gondii, facilitating the deciphering of the mechanisms of egress of eimerian parasites.

  7. Window Stories

    DEFF Research Database (Denmark)

    Hauge, Bettina

    strategies for overheating or to communicate with people in a more user informed way. The people participating in the study lived in different houses and had different backgrounds. They were involved in the project over a period of 3-4 months. The prolonged participation was facilitated through a variety......, as well as the opposite. The report also includes a special focus on overheating and people’s strategies against this. Knowing about what people appreciate in a window and their actual practices and the reasons for their behaviour may be useful in many different ways, for instance to inform public...

  8. Strategic Windows

    DEFF Research Database (Denmark)

    Risberg, Annette; King, David R.; Meglio, Olimpia

    We examine the importance of speed and timing in acquisitions with a framework that identifies management considerations for three interrelated acquisition phases (selection, deal closure and integration) from an acquiring firm’s perspective. Using a process perspective, we pinpoint items within...... acquisition phases that relate to speed. In particular, we present the idea of time-bounded strategic windows in acquisitions consistent with the notion of kairòs, where opportunities appear and must be pursued at the right time for success to occur....

  9. Window shopping

    OpenAIRE

    Shy, Oz

    2013-01-01

    The terms "window shopping" and "showrooming" refer to the activity in which potential buyers visit a brick-and-mortar store to examine a product but end up either not buying it or buying the product from an online retailer. This paper analyzes potential buyers who differ in their preference for after-sale service that is not offered by online retailers. For some buyers, making a trip to the brick-and-mortar store is costly; however, going to the store to examine the product has the advantage...

  10. Window shopping

    OpenAIRE

    SHY, Oz

    2013-01-01

    The terms "window shopping" and "showrooming" refer to the activity in which potential buyers visit a brick-and-mortar store to examine a product but end up either not buying it or buying the product from an online retailer. This paper analyzes potential buyers who differ in their preference for after-sale service that is not offered by online retailers. For some buyers, making a trip to the brick-and-mortar store is costly; however, going to the store to examine the product has the advantage...

  11. Cytoplasmic free Ca2+ is essential for multiple steps in malaria parasite egress from infected erythrocytes

    Directory of Open Access Journals (Sweden)

    Glushakova Svetlana

    2013-01-01

    Full Text Available Abstract Background Egress of Plasmodium falciparum, from erythrocytes at the end of its asexual cycle and subsequent parasite invasion into new host cells, is responsible for parasite dissemination in the human body. The egress pathway is emerging as a coordinated multistep programme that extends in time for tens of minutes, ending with rapid parasite extrusion from erythrocytes. While the Ca2+ regulation of the invasion of P. falciparum in erythrocytes is well established, the role of Ca2+ in parasite egress is poorly understood. This study analysed the involvement of cytoplasmic free Ca2+ in infected erythrocytes during the multistep egress programme of malaria parasites. Methods Live-cell fluorescence microscopy was used to image parasite egress from infected erythrocytes, assessing the effect of drugs modulating Ca2+ homeostasis on the egress programme. Results A steady increase in cytoplasmic free Ca2+ is found to precede parasite egress. This increase is independent of extracellular Ca2+ for at least the last two hours of the cycle, but is dependent upon Ca2+ release from internal stores. Intracellular BAPTA chelation of Ca2+ within the last 45 minutes of the cycle inhibits egress prior to parasitophorous vacuole swelling and erythrocyte membrane poration, two characteristic morphological transformations preceding parasite egress. Inhibitors of the parasite endoplasmic reticulum (ER Ca2+-ATPase accelerate parasite egress, indicating that Ca2+ stores within the ER are sufficient in supporting egress. Markedly accelerated egress of apparently viable parasites was achieved in mature schizonts using Ca2+ ionophore A23187. Ionophore treatment overcomes the BAPTA-induced block of parasite egress, confirming that free Ca2+ is essential in egress initiation. Ionophore treatment of immature schizonts had an adverse effect inducing parasitophorous vacuole swelling and killing the parasites within the host cell. Conclusions The parasite egress

  12. RUGGED CERAMIC WINDOW FOR RF APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    MIKE NEUBAUER

    2012-11-01

    High-current RF cavities that are needed for many accelerator applications are often limited by the power transmission capability of the pressure barriers (windows) that separate the cavity from the power source. Most efforts to improve RF window design have focused on alumina ceramic, the most popular historical choice, and have not taken advantage of new materials. Alternative window materials have been investigated using a novel Merit Factor comparison and likely candidates have been tested for the material properties which will enable construction in the self-matched window configuration. Window assemblies have also been modeled and fabricated using compressed window techniques which have proven to increase the power handling capability of waveguide windows. Candidate materials have been chosen to be used in fabricating a window for high power testing at Thomas Jefferson National Accelerator Facility.

  13. Astronaut Scott Carpenter completes top egress training in white room

    Science.gov (United States)

    1962-01-01

    Project Mercury Astronaut M. Scott Carpenter, prime pilot of the Mercury-Atlas 7 (the nation's second manned orbital flight), completing top egress training in the white room at Cape Canaveral, Florida. The line he is holding is known as the 'man line' which attaches the survival kit to the astronaut. The bag is the survival kit he carries for contingency landings. Clearly visible around his neck is the bag containing the life vest.

  14. Measurement of fenestration net energy performance: considerations leading to development of the mobile window thermal test (MoWiTT) facility

    Energy Technology Data Exchange (ETDEWEB)

    Klems, J.H.

    1984-07-01

    A detailed consideration of the energy flows entering the energy balance on a building space and the effect of random measurement errors on the determination of fenestration performance is presented. Estimates of the error magnitudes are made for a passive test cell and it is shown that a more accurate test facility is necessary for reliable measurements on fenestration systems with thermal resistance in the range 2 to 10 times that of single glazing or shading coefficient less than 0.7. A test facility of this type, the MoWiTT, which has been built at Lawrence Berkeley Laboratory, is described. The effect of random errors in the MoWiTT is discussed and computer calculations of its performance are presented. The discussion shows that, for any measurement facility, random errors are most serious for nighttime measurements, while systematic errors are most important for daytime measurements. It is concluded that, for the MoWiTT, errors from both sources are expected to be small.

  15. Gasochromic windows

    Energy Technology Data Exchange (ETDEWEB)

    Wittwer, V.; Datz, M.; Ell, J.; Georg, A.; Graf, W.; Walze, G. [Fraunhofer Institute for Solar Energy Systems, Freiburg (Germany)

    2004-10-01

    Gasochromic windows can change their transmittance over a wide range. This change is caused by a thin layer of tungsten oxide (WO{sub 3}), covered by a very thin layer of platinum. Exposing this coating to diluted hydrogen gas leads to reduction of the WO{sub 3}, resulting in colouring. This process can be reversed by introducing diluted oxygen. The hydrogen and oxygen are produced by an electrolyser. Only small amounts of gas are needed for the switching process. The coatings are produced by sputtering. Water is needed in the WO{sub 3} films to allow rapid transport of the hydrogen. However, this water should not escape when the system is operated at higher temperatures, which can exceed 60 deg C. By adjusting the conditions of the sputtering process appropriately, a large amount of water can be incorporated in the films, which remains even up to temperatures above 100 deg C. The best transmittance values obtained for a coated double-glazed unit with a moderate film thickness (560 nm) and hydrogen concentrations below the combustion limit are 76% and 77% for solar and visual transmittance, respectively, in the bleached state and 5% and 6% for solar and visual transmittance, respectively, in the coloured state. Darker states can be obtained by applying thicker films of tungsten oxide without reducing the transmittance in the bleached state. Gasochromic coatings can also be deposited easily on plastic substrates and - because their coating structure is so simple - combined with prismatic microstructures, which allow light to be redirected. In addition, the gasochromic systems technology can be used with metal hydride systems. (Author)

  16. Thermal performance measurements of sealed insulating glass units with low-E coatings using the MoWiTT (Mobile Window Thermal Test) field-test facility

    Energy Technology Data Exchange (ETDEWEB)

    Klems, J.; Keller, H.

    1986-12-01

    Using data obtained in a mobile field-test facility, measured performance of clear and low-emissivity double-glazing units is presented for south-facing and north-facing orientations. The changes in U-value and shading coefficient resulting from addition of the low-E coating are found to agree with theoretical expectations for the cold spring test conditions. Accurate nighttime U-values were derived from the data and found to agree with calculations. Expected correlation between U-value and wind speed was not observed in the data; a plausible experimental reason for this is advanced.

  17. Experimental study of plasma window

    CERN Document Server

    Ben-Liang, Shi; Kun, Zhu; Yuan-Rong, Lu

    2013-01-01

    Plasma window is an advanced apparatus which can work as the interface between vacuum and high pressure region. It can be used in many applications which need atmosphere-vacuum interface, such as gas target, electron beam welding, synchrotron radiation and spallation neutron source. A test bench of plasma window is constructed in Peking University. A series of experiments and corresponding parameter measurements have been presented in this article. The experiment result indicates the feasibility of such a facility acting as an interface between vacuum and high pressure region.

  18. A genetic screen to isolate Toxoplasma gondii host-cell egress mutants.

    Science.gov (United States)

    Coleman, Bradley I; Gubbels, Marc-Jan

    2012-02-08

    The widespread, obligate intracellular, protozoan parasite Toxoplasma gondii causes opportunistic disease in immuno-compromised patients and causes birth defects upon congenital infection. The lytic replication cycle is characterized by three stages: 1. active invasion of a nucleated host cell; 2. replication inside the host cell; 3. active egress from the host cell. The mechanism of egress is increasingly being appreciated as a unique, highly regulated process, which is still poorly understood at the molecular level. The signaling pathways underlying egress have been characterized through the use of pharmacological agents acting on different aspects of the pathways. As such, several independent triggers of egress have been identified which all converge on the release of intracellular Ca(2+), a signal that is also critical for host cell invasion. This insight informed a candidate gene approach which led to the identification of plant like calcium dependent protein kinase (CDPK) involved in egress. In addition, several recent breakthroughs in understanding egress have been made using (chemical) genetic approaches. To combine the wealth of pharmacological information with the increasing genetic accessibility of Toxoplasma we recently established a screen permitting the enrichment for parasite mutants with a defect in host cell egress. Although chemical mutagenesis using N-ethyl-N-nitrosourea (ENU) or ethyl methanesulfonate (EMS) has been used for decades in the study of Toxoplasma biology, only recently has genetic mapping of mutations underlying the phenotypes become routine. Furthermore, by generating temperature-sensitive mutants, essential processes can be dissected and the underlying genes directly identified. These mutants behave as wild-type under the permissive temperature (35 °C), but fail to proliferate at the restrictive temperature (40 °C) as a result of the mutation in question. Here we illustrate a new phenotypic screening method to isolate mutants

  19. Measurement of single and double glazing thermal performance under realistic conditions using the mobile window thermal test (MoWiTT) facility

    Energy Technology Data Exchange (ETDEWEB)

    Klems, J.; Keller, H.

    1986-11-01

    The thermal performance of single glazing, clear double glazing, and double glazing with a low-emissivity coating was measured in both south-facing and north-facing orientations under realistic field conditions using the new MoWiTT field test facility. The time-dependent net heat flow through each fenestration was found to be consistent with the predictions of the standard simplified heat transfer model, provided that an angle-dependent shading coefficient is used and diffuse solar gain is included in the calculation. Summer-condition average U-values were derived for each glazing type and were found to agree with the expected values for both types of double glazing. The measured U-value for single glazing was lower than predicted.

  20. Non-Pulmonic-Egressive Speech in Clinical Data: A Brief Review

    Science.gov (United States)

    Ball, Martin J.; Muller, Nicole

    2007-01-01

    This review examines the literature on the use of non-pulmonic egressive sounds in disordered speech. Studies are described that report the use of pulmonic ingressive speech, clicks, ejectives, and implosives. Broad trends are identified linking the use of each type of non-pulmonic-egressive airstream use with particular disorders. The importance…

  1. Heart Rate Responses to Unaided Orion Side Hatch Egress in the Neutral Buoyancy Laboratory

    Science.gov (United States)

    English, Kirk L.; Hwang, Emma Y.; Ryder, Jeffrey W.; Kelly, Cody; Walker, Thomas; Ploutz-Snyder, Lori

    2016-01-01

    The Orion capsule will be the next NASA-built vehicle used for near and deep space exploration. The nominal landing scenario for Orion involves splashdown in the Pacific Ocean and subsequent aided crew egress conducted by military personnel. Contingency operations, however, require the crew to egress the capsule unaided, deploy an inflatable life raft, and to ingress the raft. Unaided egress is expected to be physiologically demanding, but no data exist to corroborate this. Thus, we evaluated the heart rate response to unaided Orion side hatch egress and raft ingress as par of the NASA crew Survival Engineering Team's evaluation of egress procedures using the Post-landing Orion Recovery Trainer (PORT) article in the Neutral Buoyancy Laboratory (NBL).

  2. Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection.

    Directory of Open Access Journals (Sweden)

    Milly M Choy

    2015-11-01

    Full Text Available The mosquito-borne dengue virus (DENV is a cause of significant global health burden, with an estimated 390 million infections occurring annually. However, no licensed vaccine or specific antiviral treatment for dengue is available. DENV interacts with host cell factors to complete its life cycle although this virus-host interplay remains to be fully elucidated. Many studies have identified the ubiquitin proteasome pathway (UPP to be important for successful DENV production, but how the UPP contributes to DENV life cycle as host factors remains ill defined. We show here that proteasome inhibition decouples infectious virus production from viral RNA replication in antibody-dependent infection of THP-1 cells. Molecular and imaging analyses in β-lactone treated THP-1 cells suggest that proteasome function does not prevent virus assembly but rather DENV egress. Intriguingly, the licensed proteasome inhibitor, bortezomib, is able to inhibit DENV titers at low nanomolar drug concentrations for different strains of all four serotypes of DENV in primary monocytes. Furthermore, bortezomib treatment of DENV-infected mice inhibited the spread of DENV in the spleen as well as the overall pathological changes. Our findings suggest that preventing DENV egress through proteasome inhibition could be a suitable therapeutic strategy against dengue.

  3. Improved Emergency Egress Lighting System for the ISS

    Science.gov (United States)

    Eaton, Leslie L.; Barr, Don A.

    2005-01-01

    Emergency lights provide illumination in corridors, stairwells, ramps, escalators, aisles, and exit passageways during power failures. Safety and visibility are critical during a power outage. If emergency lights fail to operate properly, the building occupants can become disoriented. Four documents in a collection discuss different topics relating to a proposed improved emergency egress lighting system (EELS) for the International Space Station (ISS). While the present EELS is designed around rows of green-light-emitting diodes, the proposed system contains strips of electroluminescent tape using different colors for each egress path. The proposed EELS can be powered by the same battery currently used by the present EELS, but would require an inverter because electroluminescent devices require AC. Electroluminescent devices also require significantly less current and, depending on the color, would emit 3 to 8 times the light of the present EELS. In addition, they could operate for up to 75 hours (versus .20 minutes for the present system). The first document contains a one-page summary of the proposal and an evaluation of technical merit. The second document summarizes the motivation for, and the design of, the proposed EELS. The third document addresses relevant aspects of the measurement of spectral sensitivity and the psychophysics of perception of light. The fourth document presents additional background information and technical specifications for the electroluminescent tapes.

  4. Windows 10 for dummies

    CERN Document Server

    Rathbone, Andy

    2015-01-01

    The fast and easy way to get up and running with Windows 10 Windows 10 For Dummies covers the latest version of Windows and gets you up and running with the changes and new features you'll find in this updated operating system. Packed with time-saving tips to help you get the most out of the software, this helpful Windows 10 guide shows you how to manage Windows tasks like navigating the interface with a mouse or touchscreen, connecting to the web, and troubleshooting problems and making quick fixes. Assuming no prior knowledge of the software, Windows 10 For Dummies addresses the updates to

  5. Windows 10 simplified

    CERN Document Server

    McFedries, Paul

    2015-01-01

    Learn Windows 10 quickly and painlessly with this beginner's guide Windows 10 Simplified is your absolute beginner's guide to the ins and outs of Windows. Fully updated to cover Windows 10, this highly visual guide covers all the new features in addition to the basics, giving you a one-stop resource for complete Windows 10 mastery. Every page features step-by-step screen shots and plain-English instructions that walk you through everything you need to know, no matter how new you are to Windows. You'll master the basics as you learn how to navigate the user interface, work with files, create

  6. Brucella Dissociation Is Essential for Macrophage Egress and Bacterial Dissemination

    Directory of Open Access Journals (Sweden)

    Thomas A Ficht

    2014-03-01

    Full Text Available It has long been observed that smooth Brucella can dissociate into rough mutants that are cytotoxic to macrophages. However, the in vivo biological significance and/or mechanistic de-tails of Brucella dissociation and cytotoxicity remain incomplete. In the current report, a plaque assay was developed using Brucella strains exhibiting varying degrees of cytotoxicity. Infected monolayers were observed daily using phase contrast microscopy for plaque formation while Brucella uptake and replication were monitored using an immunofluorescence assay (IFA. Vis-ible plaques were detected at 4-5 days post infection (p.i. with cytotoxic Brucella 16M∆manBA at an MOI of 0.1. IFA staining demonstrated that the plaques consisted of macrophages with replicating Brucella. Visible plaques were not detected in monolayers infected with non-cytotoxic 16M∆manBA∆virB2 at an MOI of 0.1. However, IFA staining did reveal small groups of macrophages (foci with replicating Brucella in the monolayers infected with 16M∆manBA∆virB2. The size of the foci observed in macrophage monolayers infected with rough Brucella correlated directly with cytotoxicity measured in liquid culture, suggesting that cytotoxicity was essential for Brucella egress and dissemination. In monolayers infected with 16M, small and large foci were observed. Double antibody staining revealed spontaneous rough mutants within the large, but not the small foci in 16M infected monolayers. Furthermore, plaque formation was observed in the large foci derived from 16M infections. Finally, the addi-tion of gentamicin to the culture medium inhibited plaque formation, suggesting that the cell-to-cell spreading occurred only following release of the organisms from the cells. Taken together, these results demonstrate that Brucella induced cytotoxicity is critical for Brucella egress and dissemination.

  7. Brucella dissociation is essential for macrophage egress and bacterial dissemination.

    Science.gov (United States)

    Pei, Jianwu; Kahl-McDonagh, Melissa; Ficht, Thomas A

    2014-01-01

    It has long been observed that smooth Brucella can dissociate into rough mutants that are cytotoxic to macrophages. However, the in vivo biological significance and/or mechanistic details of Brucella dissociation and cytotoxicity remain incomplete. In the current report, a plaque assay was developed using Brucella strains exhibiting varying degrees of cytotoxicity. Infected monolayers were observed daily using phase contrast microscopy for plaque formation while Brucella uptake and replication were monitored using an immunofluorescence assay (IFA). Visible plaques were detected at 4-5 days post infection (p.i.) with cytotoxic Brucella 16MΔmanBA at an MOI of 0.1. IFA staining demonstrated that the plaques consisted of macrophages with replicating Brucella. Visible plaques were not detected in monolayers infected with non-cytotoxic 16MΔmanBAΔvirB2 at an MOI of 0.1. However, IFA staining did reveal small groups of macrophages (foci) with replicating Brucella in the monolayers infected with 16MΔmanBAΔvirB2. The size of the foci observed in macrophage monolayers infected with rough Brucella correlated directly with cytotoxicity measured in liquid culture, suggesting that cytotoxicity was essential for Brucella egress and dissemination. In monolayers infected with 16M, small and large foci were observed. Double antibody staining revealed spontaneous rough mutants within the large, but not the small foci in 16M infected monolayers. Furthermore, plaque formation was observed in the large foci derived from 16M infections. Finally, the addition of gentamicin to the culture medium inhibited plaque formation, suggesting that cell-to-cell spread occurred only following release of the organisms from the cells. Taken together, these results demonstrate that Brucella-induced cytotoxicity is critical for Brucella egress and dissemination.

  8. STS-103 crew practice emergency egress in the slidewire basket

    Science.gov (United States)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist C. Michael Foale (Ph.D.) gets ready to pull the lever, which will release the basket. With Foale are fellow crew members Mission Specialists Claude Nicollier of Switzerland and John M. Grunsfeld (Ph.D.). The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members taking part are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, and Jean-Frangois Clervoy of France. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  9. Conceptual design of proton beam window

    Energy Technology Data Exchange (ETDEWEB)

    Teraoku, Takuji; Kaminaga, Masanori; Terada, Atsuhiko; Ishikura, Syuichi; Kinoshita, Hidetaka; Hino, Ryutaro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    In a MW-scale neutron scattering facility coupled with a high-intensity proton accelerator, a proton beam window is installed as the boundary between a high vacuum region of the proton beam transport line and a helium environment around the target assembly working as a neutron source. The window is cooled by water so as to remove high volumetric heat generated by the proton beam. A concept of the flat-type proton beam window consisting of two plates of 3 mm thick was proposed, which was found to be feasible under the proton beam power of 5 MW through thermal-hydraulic and structural strength analyses. (authors)

  10. Energy Efficient Window Retrofits in Historic Facilities

    Science.gov (United States)

    2006-01-01

    operation, maintenance, and monitoring of an identified energy or water conservation measure or series of measures at one or more 8 0 S 0 * locations... warer to ooler odiesthsfomw insie to utiei itr ndrvre ieto walls~ ~~~~oo an eiigst iceaeth -vle U28 H t Urmtewnnrs ot le i o idwadfaei e ineatoUfalteha

  11. Windows for Intel Macs

    CERN Document Server

    Ogasawara, Todd

    2008-01-01

    Even the most devoted Mac OS X user may need to use Windows XP, or may just be curious about XP and its applications. This Short Cut is a concise guide for OS X users who need to quickly get comfortable and become productive with Windows XP basics on their Macs. It covers: Security Networking ApplicationsMac users can easily install and use Windows thanks to Boot Camp and Parallels Desktop for Mac. Boot Camp lets an Intel-based Mac install and boot Windows XP on its own hard drive partition. Parallels Desktop for Mac uses virtualization technology to run Windows XP (or other operating systems

  12. Windows® Internals

    CERN Document Server

    Russinovich, Mark E; Ionescu, Alex

    2009-01-01

    See how the core components of the Windows operating system work behind the scenes-guided by a team of internationally renowned internals experts. Fully updated for Windows Server 2008 and Windows Vista, this classic guide delivers key architectural insights on system design, debugging, performance, and support-along with hands-on experiments to experience Windows internal behavior firsthand.Delve inside Windows architecture and internals:Understand how the core system and management mechanisms work-from the object manager to services to the registryExplore internal system data structures usin

  13. Windows 7 for dummies

    CERN Document Server

    Rathbone, Andy

    2010-01-01

    Get more done and have more fun with Windows 7 Windows 7 is loaded with features, tools, and shortcuts designedto make life easier for all users. This handy guide is sure to makeWindows as clear as can be. It helps you get started, use foldersand files, find handy gadgets, and search on your PC or online. Open the book and find: Ways to find photos, music, and video on your PCAdvice on jazzing up the Windows 7 interfaceReasons for making the switch to Windows 7Tools for staying organizedSteps for setting up your user accounts and passwords

  14. Astronaut Russell L. Schweickart on deck prior to water egress training

    Science.gov (United States)

    1968-01-01

    Astronaut Russell L. Schweickart, lunar module pilot of the Apollo 9 (Spacecraft 104/Lunar Module 3/Saturn 504) space mission, relaxes on the deck of the NASA Motor Vessel Retriever prior to water egress training in the Gulf of Mexico.

  15. The Safety of Hospital Beds: Ingress, Egress, and In-Bed Mobility.

    Science.gov (United States)

    Morse, Janice M; Gervais, Pierre; Pooler, Charlotte; Merryweather, Andrew; Doig, Alexa K; Bloswick, Donald

    2015-01-01

    To explore the safety of the standard and the low hospital bed, we report on a microanalysis of 15 patients' ability to ingress, move about the bed, and egress. The 15 participants were purposefully selected with various disabilities. Bed conditions were randomized with side rails up or down and one low bed with side rails down. We explored the patients' use of the side rails, bed height, ability to lift their legs onto the mattress, and ability to turn, egress, and walk back to the chair. The standard bed was too high for some participants, both for ingress and egress. Side rails were used by most participants when entering, turning in bed, and exiting. We recommend that side rails be reconsidered as a means to facilitate in-bed movement, ingress, and egress. Furthermore, single deck height settings for all patients are not optimal. Low beds as a safety measure must be re-evaluated.

  16. Advanced energy efficient windows

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund

    2007-01-01

    energy savings. In terms of energy, windows occupy a special position compared with other thermal envelope structures due to their many functions: 1) windows let daylight into the building and provide occupants with visual contact with their surroundings 2) windows protect against the outdoor climate 3......Windows should be paid special attention as they contribute a significant part of the total heat-loss coefficient of the building. Contrary to other parts of the thermal envelope the windows are not only heat loosers, but may gain heat in the day-time. Therefore there are possibilities for large......) windows transmit solar energy that may contribute to a reduction of energy consumption, but which may also lead to unpleasant overheating. In the following paragraphs the current use of windows is reviewed with an emphasis on energy, while special products like solar protection glazing and security...

  17. STS-56 Commander Cameron, in LES, with sky genie during JSC egress training

    Science.gov (United States)

    1992-01-01

    STS-56 Discovery, Orbiter Vehicle (OV) 103, Commander Kenneth Cameron, wearing launch and entry suit (LES), gives the sky-genie escape device a tug as training instructor Kenneth D. Trujillo holds it in position and explains its operation. Cameron, along with the other STS-56 crewmembers, is briefed on emergency egress procedures at JSC's Mockup and Integration Laboratory (MAIL) Bldg 9NE prior to a training simulation. The sky-genie is carried on all Space Shuttle flights for emergency egress purposes.

  18. A Genetic Screen to Isolate Toxoplasma gondii Host-cell Egress Mutants

    OpenAIRE

    Coleman, Bradley I.; Gubbels, Marc-Jan

    2012-01-01

    The widespread, obligate intracellular, protozoan parasite Toxoplasma gondii causes opportunistic disease in immuno-compromised patients and causes birth defects upon congenital infection. The lytic replication cycle is characterized by three stages: 1. active invasion of a nucleated host cell; 2. replication inside the host cell; 3. active egress from the host cell. The mechanism of egress is increasingly being appreciated as a unique, highly regulated process, which is still poorly understo...

  19. STS-93 Pilot Ashby takes part in emergency egress training

    Science.gov (United States)

    1999-01-01

    STS-93 Pilot Jeffrey S. Ashby pauses for the photographer before climbing into an M-113 armored personnel carrier at the launch pad to take part in emergency egress training. In preparation for their mission, the STS-93 crew are participating in Terminal Countdown Demonstration Test activities that also include a launch-day dress rehearsal culminating with a simulated main engine cut-off. Others in the crew are Commander Eileen M. Collins and Mission Specialists Steven A. Hawley (Ph.D.), Catherine G. Coleman (Ph.D.), and Michel Tognini of France, who represents the Centre National d'Etudes Spatiales (CNES). Collins is the first woman to serve as a mission commander. The primary mission of STS-93 is the release of the Chandra X-ray Observatory, which will allow scientists from around the world to obtain unprecedented X-ray images of exotic environments in space to help understand the structure and evolution of the universe. Chandra is expected to provide unique and crucial information on the nature of objects ranging from comets in our solar system to quasars at the edge of the observable universe. Since X-rays are absorbed by the Earth's atmosphere, space-based observatories are necessary to study these phenomena and allow scientists to analyze some of the greatest mysteries of the universe. The targeted launch date for STS-93 is no earlier than July 20 at 12:36 a.m. EDT from Launch Pad 39B.

  20. Beginning Windows 8

    CERN Document Server

    Halsey, Mike

    2012-01-01

    Windows 8 has been described by Microsoft as its 'boldest' Windows release ever. Beginning Windows 8 takes you through the new features and helps you get more out of the familiar to reveal the possibilities for this amazing new operating system. You will learn, with non-technical language used throughout, how to get up and running in the new Windows interface, minimize downtime, maximize productivity, and harness the features you never knew existed to take control of your computer and enjoy the peace of mind and excitement that comes with it. From tips and tweaks to easy-to-follow guides and d

  1. Programming Windows Azure

    CERN Document Server

    Krishnan, Sriram

    2010-01-01

    Learn the nuts and bolts of cloud computing with Windows Azure, Microsoft's new Internet services platform. Written by a key member of the product development team, this book shows you how to build, deploy, host, and manage applications using Windows Azure's programming model and essential storage services. Chapters in Programming Windows Azure are organized to reflect the platform's buffet of services. The book's first half focuses on how to write and host application code on Windows Azure, while the second half explains all of the options you have for storing and accessing data on the plat

  2. Mastering Windows 7 Deployment

    CERN Document Server

    Finn, Aidan; van Surksum, Kenneth

    2011-01-01

    Get professional-level instruction on Windows 7 deployment tools Enterprise-level operating system deployment is challenging and requires knowledge of specific tools. It is expected that Windows 7 will be extensively deployed in businesses worldwide. This comprehensive Sybex guide provides thorough coverage of the Microsoft deployment tools that were specifically created for Windows 7, preparing system administrators, MIS professionals, and corporate programmers to tackle the task effectively.Companies worldwide are expected to deploy Windows 7 as their enterprise operating system; system admi

  3. Windows 8 secrets

    CERN Document Server

    Thurrott, Paul

    2012-01-01

    Tips, tricks, treats, and secrets revealed on Windows 8 Microsoft is introducing a major new release of its Windows operating system, Windows 8, and what better way to learn all its ins and outs than from two internationally recognized Windows experts and Microsoft insiders, authors Paul Thurrott and Rafael Rivera? They cut through the hype to get at useful information you'll not find anywhere else, including what role this new OS plays in a mobile and tablet world. Regardless of your level of knowledge, you'll discover little-known facts about how things work, what's new and different, and h

  4. CXCR4 is dispensable for T cell egress from chronically inflamed skin via the afferent lymph.

    Directory of Open Access Journals (Sweden)

    Skye A Geherin

    Full Text Available T cell recirculation through extralymphoid tissues is essential to immune surveillance, host defense and inflammation. In this process, T cells enter the tissue from the blood and subsequently leave via the afferent lymph. In the absence of inflammation, T cells require CCR7 expression to egress from the skin or lung, which is consistent with the constitutive expression of the CCR7 ligand CCL21 on lymphatic endothelium. However, during chronic inflammation alternative chemoattractants come into play, allowing Ccr7-deficient (Ccr7-/- T cells to egress efficiently from affected skin. As T cell egress from inflamed sites is a potential control point of the inflammatory response, we aimed to determine alternative T cell exit receptors using a mouse and a sheep model. We show that CCR7+ and CCR7- T cells exiting from the chronically inflamed skin were highly responsive to the CXCR4 ligand CXCL12, which was induced in the lymphatics in the inflamed site. Based on these findings, we hypothesized that CXCR4 mediates T cell egress from inflamed skin. However, pharmacological inhibition of CXCR4 did not affect the tissue egress of wildtype or Ccr7-/- CD4 and CD8 T cells after adoptive transfer into chronically inflamed skin. Similarly, adoptively transferred Cxcr4-/- Ccr7-/- and Ccr7-/- T cells egressed from the inflamed skin equally well. Based on these data, we conclude that, while CXCR4 might play an essential role for other cell types that enter the afferent lymphatics, it is dispensable for T cell egress from the chronically inflamed skin.

  5. Air transparent soundproof window

    Directory of Open Access Journals (Sweden)

    Sang-Hoon Kim

    2014-11-01

    Full Text Available A soundproof window or wall which is transparent to airflow is presented. The design is based on two wave theories: the theory of diffraction and the theory of acoustic metamaterials. It consists of a three-dimensional array of strong diffraction-type resonators with many holes centered on each individual resonator. The negative effective bulk modulus of the resonators produces evanescent wave, and at the same time the air holes with subwavelength diameter existed on the surfaces of the window for macroscopic air ventilation. The acoustic performance levels of two soundproof windows with air holes of 20mm and 50mm diameters were measured. The sound level was reduced by about 30 - 35dB in the frequency range of 400 - 5,000Hz with the 20mm window, and by about 20 - 35dB in the frequency range of 700 - 2,200Hz with the 50mm window. Multi stop-band was created by the multi-layers of the window. The attenuation length or the thickness of the window was limited by background noise. The effectiveness of the soundproof window with airflow was demonstrated by a real installation.

  6. Efficient Windows Collaborative

    Energy Technology Data Exchange (ETDEWEB)

    Nils Petermann

    2010-02-28

    The project goals covered both the residential and commercial windows markets and involved a range of audiences such as window manufacturers, builders, homeowners, design professionals, utilities, and public agencies. Essential goals included: (1) Creation of 'Master Toolkits' of information that integrate diverse tools, rating systems, and incentive programs, customized for key audiences such as window manufacturers, design professionals, and utility programs. (2) Delivery of education and outreach programs to multiple audiences through conference presentations, publication of articles for builders and other industry professionals, and targeted dissemination of efficient window curricula to professionals and students. (3) Design and implementation of mechanisms to encourage and track sales of more efficient products through the existing Window Products Database as an incentive for manufacturers to improve products and participate in programs such as NFRC and ENERGY STAR. (4) Development of utility incentive programs to promote more efficient residential and commercial windows. Partnership with regional and local entities on the development of programs and customized information to move the market toward the highest performing products. An overarching project goal was to ensure that different audiences adopt and use the developed information, design and promotion tools and thus increase the market penetration of energy efficient fenestration products. In particular, a crucial success criterion was to move gas and electric utilities to increase the promotion of energy efficient windows through demand side management programs as an important step toward increasing the market share of energy efficient windows.

  7. Color Wheel Windows

    Science.gov (United States)

    Leonard, Stephanie

    2012-01-01

    In this article, the author describes a painting and drawing lesson which was inspired by the beautiful circular windows found in cathedrals and churches (also known as "rose windows"). This two-week lesson would reinforce both the concept of symmetry and students' understanding of the color wheel. (Contains 1 online resource.)

  8. Multi-functional windows

    Science.gov (United States)

    Nag, Nagendra; Goldman, Lee M.; Balasubramanian, Sreeram; Sastri, Suri

    2013-06-01

    The requirements for modern aircraft are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the physical properties of optically transparent materials currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows held in weight bearing frames. Novel material systems will have to be developed which combine different materials (e.g. ductile metals with transparent ceramics) into structures that combine transparency with structural integrity. Surmet's demonstrated ability to produce novel transparent ceramic/metal structures will allow us to produce such structures in the types of conformal shapes required for future aircraft applications. Furthermore, the ability to incorporate transparencies into such structures also holds out the promise of creating multi-functional windows which provide a broad range of capabilities that might include RF antennas and de-icing in addition to transparency. Recent results in this area will be presented.

  9. Visual merchandising window display

    Directory of Open Access Journals (Sweden)

    Opris (Cas. Stanila M.

    2013-12-01

    Full Text Available Window display plays a major part in the selling strategies; it does not only include the simple display of goods, nowadays it is a form of art, also having the purpose of sustaining the brand image. This article wants to reveal the tools that are essential in creating a fabulous window display. Being a window designer is not an easy job, you have to always think ahead trends, to have a sense of colour, to know how to use light to attract customers in the store after only one glance at the window. The big store window displays are theatre scenes: with expensive backgrounds, special effects and high fashion mannequins. The final role of the displays is to convince customers to enter the store and trigger the purchasing act which is the final goal of the retail activity.

  10. Preparation of the Human Cytomegalovirus Nuclear Egress Complex and Associated Proteins.

    Science.gov (United States)

    Sharma, Mayuri; Kamil, Jeremy P; Coen, Donald M

    2016-01-01

    Herpesviruses, like most DNA viruses, replicate their genomes in the host cell nucleus. Their DNA is then packaged and assembled into viral nucleocapsids, which, in most cases, are too large to pass through the nuclear pore complex. Instead, herpesviruses use a complex multistep pathway, termed nuclear egress, to exit the nucleus. Key players in this process include two conserved viral proteins that form the nuclear egress complex (NEC). In human cytomegalovirus, these NEC proteins are UL50, embedded in the inner nuclear membrane, and its nucleoplasmic partner UL53. Both are essential for viral nuclear egress. However, other viral components as well as host nuclear envelope proteins may also participate in nuclear egress. Identifying these viral and cellular factors may provide important insight into the herpesvirus lifecycle and its relationship to the underlying, yet still-mysterious, host nuclear egress pathway. We developed an immunoprecipitation-based protocol, described herein, to identify protein-protein interactions involving the NEC from the nuclear fraction of infected cells that express an epitope-tagged version of NEC subunit UL53.

  11. Calcium-dependent microneme protein discharge and in vitro egress of Eimeria tenella sporozoites.

    Science.gov (United States)

    Yan, Xinlei; Tao, Geru; Liu, Xianyong; Ji, Yongsheng; Suo, Xun

    2016-11-01

    Egress is a vital step in the endogenous development of apicomplexan parasites, as it assures the parasites exit from consumed host cells and entry into fresh ones. However, little information has previously been reported on this step of Eimeria spp. In this study, we investigated in vitro egress of Eimeria tenella sporozoites triggered by acetaldehyde. We found that addition of exogenous acetaldehyde induces egress of sporozoites from primary chicken kidney cells (PCKs) and stimulate secretion of E. tenella microneme 2 protein (EtMic 2). Moreover, by using cellular calcium inhibitors, we further proved that these processes were dependent on the intracellular calcium of the parasites. Our findings provide clues to the study of interaction between eimerian parasites and their hosts.

  12. Rails on Windows

    CERN Document Server

    Hibbs, Curt

    2007-01-01

    It's no secret that the entire Ruby onRails core team uses OS X as their preferreddevelopment environment. Becauseof this, it is very easy to findauthoritative information on the webabout using Rails on OS X. But the truthis that Windows developers using Railsprobably outnumber those using otherplatforms. A Windows development environmentcan be just as productive asany other platform. This is a guide to developing with Rubyon Rails under Windows. It won't teachyou how to write Ruby on Rails web applications,but it will show you what toolsto use and how to set them up to createa complete Rail

  13. Windows 7 resource kit

    CERN Document Server

    Northrup, Tony; Honeycutt, Jerry; Wilson, Ed

    2009-01-01

    In-depth and comprehensive, this RESOURCE KIT delivers the information you need to administer your Windows 7 system. You get authoritative technical guidance from those who know the technology best-Microsoft Most Valuable Professionals (MVPs) and the Windows 7 product team-along with essential scripts and resources. In addition, "Direct from the Source" sidebars offer deep insights and troubleshooting tips from the Windows 7 team. Get expert guidance on how to: Use Microsoft Deployment Toolkit best practices and tools. Plan user-state migration and test application compatibility.

  14. Windows 8 simplified

    CERN Document Server

    McFedries, Paul

    2012-01-01

    The easiest way for visual learners to get started with Windows 8 The popular Simplified series makes visual learning easier than ever, and with more than 360,000 copies sold, previous Windows editions are among the bestselling Visual books. This guide goes straight to the point with easy-to-follow, two-page tutorials for each task. With full-color screen shots and step-by-step directions, it gets beginners up and running on the newest version of Windows right away. Learn to work with the new interface and improved Internet Explorer, manage files, share your computer, and much more. Perfect fo

  15. Windows 95 Beslutningsguide

    DEFF Research Database (Denmark)

    Sørensen, Jens Otto

    1996-01-01

    Mange virksomheder der bruger pc'er står netop nu over for valget: Skal vi fortsætte med DOS/Windows 3.x som operativsystem, eller skal vi skifte til efterfølgeren Windows 95? Skal vi/kan vi skifte successivt, eller skal det være en "alt eller intet beslutning". Hvornår er det rigtige tidspunkt...... at skifte? Denne artikel vil forsøge at give en baggrundsviden om Windows 95, der kan hjælpe virksomhederne igennem denne beslutningsfase....

  16. The Efficient Windows Collaborative

    Energy Technology Data Exchange (ETDEWEB)

    Petermann, Nils

    2006-03-31

    The Efficient Windows Collaborative (EWC) is a coalition of manufacturers, component suppliers, government agencies, research institutions, and others who partner to expand the market for energy efficient window products. Funded through a cooperative agreement with the U.S. Department of Energy, the EWC provides education, communication and outreach in order to transform the residential window market to 70% energy efficient products by 2005. Implementation of the EWC is managed by the Alliance to Save Energy, with support from the University of Minnesota and Lawrence Berkeley National Laboratory.

  17. Experimental study of the plasma window

    Science.gov (United States)

    Shi, Ben-Liang; Huang, Sheng; Zhu, Kun; Lu, Yuan-Rong

    2014-01-01

    The plasma window is an advanced apparatus that can work as the interface between a vacuum and a high pressure region. It can be used in many applications that need atmosphere-vacuum interface, such as a gas target, electron beam welding, synchrotron radiation and a spallation neutron source. A test bench of the plasma window is constructed in Peking University. A series of experiments and the corresponding parameter measurements have been presented in this article. The experiment result indicates the feasibility of such a facility acting as an interface between a vacuum and a high pressure region.

  18. Windows 10 Technical Preview

    OpenAIRE

    Jyväsjärvi, Teppo

    2015-01-01

    Tässä opinnäytetyössä tutustaan uuden kesällä 2015 virallisesti julkaistavan Windows 10 -käyttöjärjestelmän Technical Preview -kehitysversioon. Ensimmäinen Technical Preview -versio julkaistiin syksyllä 2014. Opinnäytetyössä tutustaan Windows 10:n uusin ominaisuuksiin ja tehdään vertailua aiemman Windows 8.1 -version kanssa. Työssä Windows 10 Technical Preview asennetaan virtuaalikoneelle, käydään läpi asennuksen eri vaiheet sekä suurimmat muutokset käyttöliittymässä ja sovelluksissa. Op...

  19. Delineating the conformal window

    DEFF Research Database (Denmark)

    Frandsen, Mads Toudal; Pickup, Thomas; Teper, Michael

    2011-01-01

    We identify and characterise the conformal window in gauge theories relevant for beyond the standard model building, e.g. Technicolour, using the criteria of metric confinement and causal analytic couplings, which are known to be consistent with the phase diagram of supersymmetric QCD from Seiberg...... duality. Using these criteria we find perturbation theory to be consistent throughout the predicted conformal window for several of these gauge theories and we discuss recent lattice results in the light of our findings....

  20. Windows Security patch required

    CERN Multimedia

    2003-01-01

    This concerns Windows PCs (XP, 2000, NT) which are NOT centrally managed at CERN for security patches, e.g. home PCs, experiment PCs, portables, ... A security hole which can give full privileges on Windows systems needs to be URGENTLY patched. Details of the security hole and hotfix are at: http://cern.ch/it-div/news/hotfix-MS03-026.asp http://www.microsoft.com/technet/security/bulletin/MS03-026.asp

  1. Windows Security patch required

    CERN Multimedia

    2003-01-01

    This concerns Windows PCs which are NOT centrally managed at CERN for security patches, e.g. home PCs, experiment PCs, portables, ... A security hole which can give full privileges on Windows systems needs to be URGENTLY patched. Details of the security hole and hotfix are at: http://cern.ch/it-div/news/hotfix-MS03-026.asp http://www.microsoft.com/technet/security/bulletin/MS03-026.asp

  2. Windows Security patch required

    CERN Multimedia

    3004-01-01

    This concerns Windows PCs (XP, 2000, NT) which are NOT centrally managed at CERN for security patches, e.g. home PCs, experiment PCs, portables,... A security hole which can give full privileges on Windows systems needs to be URGENTLY patched. Details of the security hole and hotfix are at: http://cern.ch/it-div/news/hotfix-MS03-026.asp http://www.microsoft.com/technet/security/bulletin/MS03-026.asp

  3. Windows Security patch required

    CERN Multimedia

    2003-01-01

    This concerns Windows PCs (XP, 2000, NT) which are NOT centrally managed at CERN for security patches, e.g. home PCs, experiment PCs, portables,... A security hole which can give full privileges on Windows systems needs to be URGENTLY patched. Details of the security hole and hotfix are at: http://cern.ch/it-div/news/hotfix-MS03-026.asp http://www.microsoft.com/technet/security/bulletin/MS03-026.asp

  4. Thin Film & Deposition Systems (Windows)

    Data.gov (United States)

    Federal Laboratory Consortium — Coating Lab: Contains chambers for growing thin film window coatings. Plasma Applications Coating Lab: Contains chambers for growing thin film window coatings. Solar...

  5. Thin Film & Deposition Systems (Windows)

    Data.gov (United States)

    Federal Laboratory Consortium — Coating Lab: Contains chambers for growing thin film window coatings. Plasma Applications Coating Lab: Contains chambers for growing thin film window coatings. Solar...

  6. Stator Blade Laser Window Research

    Science.gov (United States)

    Lugas, Grant A.

    2004-01-01

    All turbofan engines used in modern aviation contain a series of fan blades and compressor blades which are all connected to one drive shaft. Inside the jet engine between each set of blades are stator blades, which are pitched opposite of the fan and compressor blades, the stator blades are both rotational and axial fixed in place. The project that I was assigned to involves the QAT 22 fan test rig; which is currently under final design review and very soon will be fabricated. The purpose of this research facility is to better understand the effects of stator blades. Stator blades are used to straiten the air in a turbine. The researcher's primary aim is to determine what the airflow is like at both the leading edge and the trailing edge of a stator blade. My work focused on designing the windows usable for both a compressor rig and a test fan rig. The difference between the two is the test fan application will be looking into a stator blade array rather than just looking at the rotor. My discussion will include a detailed explanation of how the PIV laser window system functions fiom start to finish. I will also discuss how the information is gathered and organized. Further more I plan to talk about the purpose of this kind of research and the advantages to using this technology to determine the airflow characteristics of blade designs. Finally I will discuss the researcher s conclusion on the relationship between aerodynamics of a blade and how noise is produced. NASA's main goal with this particular facility is find ways to quiet engine noise by reducing the amount of cavitations that occurs around the blades of a turbofan engine. Additional information is included in the original extended abstract.

  7. Stator Blade Laser Window Research

    Science.gov (United States)

    Lugas, Grant A.

    2004-01-01

    All turbofan engines used in modern aviation contain a series of fan blades and compressor blades which are all connected to one drive shaft. Inside the jet engine between each set of blades are stator blades, which are pitched opposite of the fan and compressor blades, the stator blades are both rotational and axial fixed in place. The project that I was assigned to involves the QAT 22 fan test rig; which is currently under final design review and very soon will be fabricated. The purpose of this research facility is to better understand the effects of stator blades. Stator blades are used to straiten the air in a turbine. The researcher's primary aim is to determine what the airflow is like at both the leading edge and the trailing edge of a stator blade. My work focused on designing the windows usable for both a compressor rig and a test fan rig. The difference between the two is the test fan application will be looking into a stator blade array rather than just looking at the rotor. My discussion will include a detailed explanation of how the PIV laser window system functions fiom start to finish. I will also discuss how the information is gathered and organized. Further more I plan to talk about the purpose of this kind of research and the advantages to using this technology to determine the airflow characteristics of blade designs. Finally I will discuss the researcher s conclusion on the relationship between aerodynamics of a blade and how noise is produced. NASA's main goal with this particular facility is find ways to quiet engine noise by reducing the amount of cavitations that occurs around the blades of a turbofan engine. Additional information is included in the original extended abstract.

  8. STS-56 Commander Cameron, in LES, during JSC emergency egress training

    Science.gov (United States)

    1992-01-01

    STS-56 Discovery, Orbiter Vehicle (OV) 103, Commander Kenneth Cameron, wearing launch and entry suit (LES), poses at the Crew Compartment Trainer (CCT) side hatch before climbing into the mockup. Cameron, along with the other STS-56 crewmembers, is participating in an emergency egress simulation at JSC's Mockup and Integration Laboratory (MAIL) Bldg 9NE.

  9. Virtual-reality-Based 3D navigation training for emergency egress from spacecraft.

    Science.gov (United States)

    Aoki, Hirofumi; Oman, Charles M; Natapoff, Alan

    2007-08-01

    Astronauts have reported spatial disorientation and navigation problems inside spacecraft whose interior visual vertical direction varies from module to module. If they had relevant preflight practice they might orient better. This experiment examined the influence of relative body orientation and individual spatial skills during VR training on a simulated emergency egress task. During training, 36 subjects were each led on 12 tours through a space station by a virtual tour guide. Subjects wore a head-mounted display and controlled their motion with a game-pad. Each tour traversed multiple modules and involved up to three changes in visual vertical direction. Each subject was assigned to one of three groups that maintained different postures: visually upright relative to the "local" module; constant orientation relative to the "station" irrespective of local visual vertical; and "mixed" (local, followed by station orientation). Groups were balanced on the basis of mental rotation and perspective-taking test scores. Subjects then performed 24 emergency egress testing trials without the tour guide. Smoke reduced visibility during the last 12 trials. Egress time, sense of direction (by pointing to origin and destination) and configuration knowledge were measured. Both individual 3D spatial abilities and orientation during training influence emergency egress performance, pointing, and configuration knowledge. Local training facilitates landmark and route learning, but station training enhances sense of direction relative to station, and, therefore, performance in low visibility. We recommend a sequence of local, followed by station, and then randomized orientation training, preferably customized to a trainee's 3D spatial ability.

  10. Evaluation of postural sway and impact forces during ingress and egress of scissor lifts at elevations.

    Science.gov (United States)

    Pan, Christopher S; Chiou, Sharon S; Kau, Tsui-Ying; Wimer, Bryan M; Ning, Xiaopeng; Keane, Paul

    2017-11-01

    Workers are at risk when entering (ingress) or exiting (egress) elevated scissor lifts. In this study, we recorded ground impact forces and postural sway from 22 construction workers while they performed ingress and egress between a scissor lift and an adjacent work surface with varying conditions: lift opening designs, horizontal and vertical gaps, and sloped work surfaces. We observed higher peak ground shear forces when using a bar-and-chain opening, with larger horizontal gap, with the lift surface more than 0.2 m below the work surface, and presence of a sloped (26°) work surface. Similar trends were observed for postural sway, except that the influence of vertical distance was not significant. To reduce slip/trip/fall risk and postural sway of workers while ingress or egress of an elevated scissor lift, we suggest scissor lifts be equipped with a gate-type opening instead of a bar-and-chain design. We also suggest the lift surface be placed no more than 0.2 m lower than the work surface and the horizontal gap between lift and work surfaces be as small as possible. Selecting a non-sloped surface to ingress or egress a scissor lift is also preferred to reduce risk. Published by Elsevier Ltd.

  11. STS-41 MS Akers looks up at mockup prior to egress training in JSC's MAIL

    Science.gov (United States)

    1990-01-01

    STS-41 Mission Specialist (MS) Thomas D. Akers, wearing launch and entry suit (LES), looks up at crew compartment trainer (CCT) prior to emergency egress training exercises. The exercises were conducted in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9A.

  12. Adaptive Liquid Crystal Windows

    Energy Technology Data Exchange (ETDEWEB)

    Taheri, Bahman; Bodnar, Volodymyr

    2011-12-31

    Energy consumption by private and commercial sectors in the U.S. has steadily grown over the last decade. The uncertainty in future availability of imported oil, on which the energy consumption relies strongly, resulted in a dramatic increase in the cost of energy. About 20% of this consumption are used to heat and cool houses and commercial buildings. To reduce dependence on the foreign oil and cut down emission of greenhouse gases, it is necessary to eliminate losses and reduce total energy consumption by buildings. To achieve this goal it is necessary to redefine the role of the conventional windows. At a minimum, windows should stop being a source for energy loss. Ideally, windows should become a source of energy, providing net gain to reduce energy used to heat and cool homes. It is possible to have a net energy gain from a window if its light transmission can be dynamically altered, ideally electronically without the need of operator assistance, providing optimal control of the solar gain that varies with season and climate in the U.S. In addition, the window must not require power from the building for operation. Resolution of this problem is a societal challenge and of national interest and will have a broad global impact. For this purpose, the year-round, allclimate window solution to provide an electronically variable solar heat gain coefficient (SHGC) with a wide dynamic range is needed. AlphaMicron, Inc. (AMI) developed and manufactured 1ft × 1ft prototype panels for the world’s first auto-adjusting Adaptive Liquid Crystal Windows (ALCWs) that can operate from sunlight without the need for external power source and demonstrate an electronically adjustable SHGC. This novel windows are based on AlphaMicron’s patented e-Tint® technology, a guesthost liquid crystal system implemented on flexible, optically clear plastic films. This technology is suitable both for OEM and aftermarket (retro-fitting) lamination to new and existing windows. Low level of

  13. Windows 8.1 bible

    CERN Document Server

    Boyce, Jim; Tidrow, Rob

    2014-01-01

    Windows 8.1 coverage that goes above and beyond all competitors? Serving as an evolutionary update to Windows 8, Windows 8.1 provides critical changes to parts of Windows 8, such as greater customization of the interface and boot operations, return of a 'start button' that reveals apps, greater integration between the two interfaces, and updates to apps. Weighing in at nearly 1000 pages, Windows 8.1 Bible provides deeper Windows insight than any other book on the market. It's valuable for both professionals needing a guide to the nooks and crannies of Windows and regular users wanting a wide

  14. Handbook on Windows and Energy

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Schultz, Jørgen Munthe; Svendsen, Sv Aa Højgaard

    The handbook on windows and energy is a general description of windows with the main focus put on the energy performance. Common window products are described by commonly used nomenclature, description of frame and sash conctructions and description of commonly used glazing types.The energy...... transmission through windows is described in detail including radiation, convection and conduction as well as solar transmittance of window glazing. The most used terms related to characterization of window energy performance are defined and calculation methods according to international standards...... are described.A method for estimation of the net energy flow on a yearly basis and/or during the heating season is presented. The method is able to combine the influence of window orientation, window size and window shape, type of glazing, frame area relative to total window area and type of spacer in sealed...

  15. The Luminaire Window

    DEFF Research Database (Denmark)

    Hansen, Ellen Kathrine

    2017-01-01

    The importance of dynamic daylight to support health and well-being has been more and more recognized. People in hospitals and health care environments have a specific need for optimized daylight conditions. Daylight penetration through window openings is crucial to stimulate circadian rhythm...... and maintain a healthy sleep-awake pattern. At the same time, the window can provide a pleasant view and connection to the surroundings and enhance the perception of the interior space and materials. All three factors are recognized as important for human well-being and health, but never the less...

  16. Microsoft Windows networking essentials

    CERN Document Server

    Gibson, Darril

    2011-01-01

    The core concepts and technologies of Windows networking Networking can be a complex topic, especially for those new to the field of IT. This focused, full-color book takes a unique approach to teaching Windows networking to beginners by stripping down a network to its bare basics, thereby making each topic clear and easy to understand. Focusing on the new Microsoft Technology Associate (MTA) program, this book pares down to just the essentials, showing beginners how to gain a solid foundation for understanding networking concepts upon which more advanced topics and technologies can be built.

  17. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  18. Windows Azure mobile services

    CERN Document Server

    Johnson, Bruce

    2013-01-01

    Get up and running with Windows Azure Mobile Services Windows Azure Mobile Services (WAMS) is a turn-key backend solution for applications, mobile or otherwise, to utilize structured storage in the cloud. It includes basic data access functionality and built-in authentication with Microsoft Account, Facebook, Twitter and Google, as well as push notification to the client app. This compact, to the point book gives you just what you need to get up and running with these tools. Demonstrates how to add, update, delete and retrieve data using standard .NET classes or REST-based requestsDescribes h

  19. Microsoft Windows Security Essentials

    CERN Document Server

    Gibson, Darril

    2011-01-01

    Windows security concepts and technologies for IT beginners IT security can be a complex topic, especially for those new to the field of IT. This full-color book, with a focus on the Microsoft Technology Associate (MTA) program, offers a clear and easy-to-understand approach to Windows security risks and attacks for newcomers to the world of IT. By paring down to just the essentials, beginners gain a solid foundation of security concepts upon which more advanced topics and technologies can be built. This straightforward guide begins each chapter by laying out a list of topics to be discussed,

  20. BERKELEY LAB WINDOW

    Energy Technology Data Exchange (ETDEWEB)

    2015-03-06

    WINDOW features include: - Microsoft Windows TM interface - algorithms for the calculation of total fenestration product U-values and Solar Heat Gain Coefficient consistent with ASHRAE SPC 142, ISO 15099, and the National Fenestration Rating Council - a Condensation Resistance Index in accordance with the NFRC 500 Standard - and integrated database of properties - imports data from other LBNL window analysis software: - Import THERM file into the Frame Library - Import records from IGDB and OPtics5 into the Glass Library for the optical properties of coated and uncoated glazings, laminates, and applied films. Program Capabilities WINDOW 7.2 offers the following features: The ability to analyze products made from any combination of glazing layers, gas layers, frames, spacers, and dividers under any environmental conditions and at any tilt; The ability to model complex glazing systems such as venetian blinds and roller shades. Directly accessible libraries of window system components, (glazing systems, glazing layers, gas fills, frame and divider elements), and environmental conditions; The choice of working in English (IP), or Systeme International (SI) units; The ability to specify the dimensions and thermal properties of each frame element (header, sills, jamb, mullion) in a window; A multi-band (wavelength-by-wavelength) spectral model; A Glass Library which can access spectral data files for many common glazing materials from the Optics5database; A night-sky radiative model; A link with the DOE-2.1E and Energy Plus building energy analysis program. Performance Indices and Other Results For a user-defined fenestration system and user-defined environmental conditions, WINDOW calculates: The U-value, solar heat gain coefficient, shading coefficient, and visible transmittance for the complete window system; The U-value, solar heat gain coefficient, shading coefficient, and visible transmittance for the glazing system (center-of-glass values); The U-values of the

  1. The Interaction of the Space Shuttle Launch and Entry Suits and Sustained Weightless on Astronaut Egress Locomotion

    Science.gov (United States)

    Greenisen, M. C.; Bishop, P. A.; Sothmann, M.

    2008-01-01

    The purpose of this study was to determine the consequences of extended periods of weightlessness during space missions on astronauts f ability to perform a simulated contingency egress while wearing either of the Launch and Entry suits immediately after space flight. In our previous lab-based study of simulated contingency egress, we found only 4 of 12 non-astronauts wearing the Launch and Entry Suit (LES) successfully completed the simulated egress. However, 4 of 4 of the previous failures (when tested wearing the LES), were then successful in completing the test wearing the Advanced Crew Escape Suit (ACES). Therefore, this study tested 21 Astronaut Volunteers wearing either the LES or ACES while performing a simulated egress on a treadmill (TM) onboard the Crew Transportation Vehicle immediately after space flight at either the Kennedy Space Center or Edwards AFB. Astronauts walked for 400 meters at 1.6m/sec with g-suit inflation level set to preflight testing levels, visor down, breathing from the suit emergency O2 supply. Metabolic, heartrate, and perceived exertion data were collected during these post-flight tests. Exactly the same preflight simulated egress tests on a TM were performed in the lab at NASA/JSC by each crewmember at L-60. Preflight testing found 2 of the 21 crewmembers were unable to complete the simulated contingency egress. Postflight, 9 crew (8 ACES, 1 LES) completed the simulated contingency egress of 400 meters at 1.6m/sec. and 12 failed to meet that standard (7 ACES, 5 LES). Preflight physiological response tests failed to identify crew capable of performing the egress vs. those who failed. However, 18 of the 21 crew did make at least 2.67 minutes into the postflight egress testing. At that point in time, heartrate was higher (P <=.20) for the failures compared to the finishers. These findings indicate that NASA fs switch to the ACES for space flight crews should be expedited.

  2. Simple cryogenic infrared window

    NARCIS (Netherlands)

    Hartemink, M.; Hartemink, M.; Godfried, H.P; Godfried, Herman

    1991-01-01

    A simple, cheap technique is reported that allows materials with both large and small thermal expansion coefficients to be mounted as windows in low temperature cryostats while at the same time avoiding thermal stresses. The construction may be thermally cycled many times with no change in its

  3. Transparent aerogel Windows

    DEFF Research Database (Denmark)

    Jensen, Karsten Ingerslev; Schultz, Jørgen Munthe

    In a recent EU FP5 project, monolithic silica aerogel was further developed with respect to the production process at pilot-scale, its properties and the application as transparent insulation material in highly insulating and transparent windows. The aerogel production process has been optimised...

  4. "Stained Glass" Landscape Windows

    Science.gov (United States)

    Vannata, Janine

    2008-01-01

    Both adults and children alike marvel at the grand vivid stained-glass windows created by American artist Louis Comfort Tiffany. Today he is commonly recognized as one of America's most influential designers and artists throughout the last nineteenth and early twentieth century. In the lesson described in this article, students created their own…

  5. Windows and lighting program

    Energy Technology Data Exchange (ETDEWEB)

    1990-06-01

    More than 30% of all energy use in buildings is attributable to two sources: windows and lighting. Together they account for annual consumer energy expenditures of more than $50 billion. Each affects not only energy use by other major building systems, but also comfort and productivity -- factors that influence building economics far more than does direct energy consumption alone. Windows play a unique role in the building envelope, physically separating the conditioned space from the world outside without sacrificing vital visual contact. Throughout the indoor environment, lighting systems facilitate a variety of tasks associated with a wide range of visual requirements while defining the luminous qualities of the indoor environment. Windows and lighting are thus essential components of any comprehensive building science program. Despite important achievements in reducing building energy consumption over the past decade, significant additional savings are still possible. These will come from two complementary strategies: (1) improve building designs so that they effectively apply existing technologies and extend the market penetration of these technologies; and (2) develop advanced technologies that increase the savings potential of each application. Both the Windows and Daylighting Group and the Lighting System Research Group have made substantial contributions in each of these areas, and continue to do so through the ongoing research summarized here. 23 refs., 16 figs.

  6. Heart Rate Responses to Unaided Orion Side Hatch Egress in the Neutral Buoyancy Laboratory

    Science.gov (United States)

    English, Kirk L.; Hwang Emma Y.; Ryder, Jeffrey W.; Kelly, Cody; Walker, Thomas; Ploutz-Snyder, Lori L.

    2016-01-01

    NASA is developing the Orion capsule as a vehicle for transporting crewmembers to and from the International Space Station (ISS) and for future human space exploration missions. Orion and other commercial vehicles are designed to splash down in the ocean where nominally support personnel will assist crewmembers in egressing the vehicle. However, off-nominal scenarios will require crewmembers to egress the vehicle unaided, deploy survival equipment, and ingress a life raft. PURPOSE: To determine the heart rate (HR) responses to unaided Orion side hatch egress and raft ingress as a part of the NASA Crew Survival Engineering Team's evaluation of the PORT Orion mockup in the Neutral Buoyancy Laboratory (NBL). METHODS: Nineteen test subjects, including four astronauts (N=19, 14 males/5 females, 38.6+/-8.4 y, 174.4+/-9.6 cm, 75.7+/-13.1 kg), completed a graded maximal test on a cycle ergometer to determine VO2peak and HRpeak and were divided into five crews of four members each; one subject served on two crews. Each crew was required to deploy a life raft, egress the Orion vehicle from the side hatch, and ingress the life raft with two 8 kg emergency packs per crew. Each crew performed this activity one to three times; a total of ten full egresses were completed. Subjects wore a suit that was similar in form, mass, and function to the Modified Advanced Crew Escape Suit (MACES) including helmet, gloves, boots, supplemental O2 bottles, and a CO2-inflated life preserver (approx.18 kg); subjects began each trial seated supine in the PORT Orion mockup with seat belts and mockup O2 and communication connections and ended each trial with all four crewmembers inside the life raft. RESULTS: VO2peak was 40.8+/-6.8 mL/kg/min (3.1+/-0.7 L/min); HRpeak was 181+/-10 bpm. Total egress time across trials was 5.0+/-1.6 min (range: 2.8-8.0 min); all subjects were able to successfully complete all trials. Average maximum HR at activity start, at the hatch opening, in the water, and in the

  7. Windows with improved energy performances

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2003-01-01

    Heat loss through windows represents a considerable part of the total heat loss from houses. However, apart from providing daylight access and view, windows offer a unique potential for solar gain to be exploited during the heating season. Until now valuation of the energy performance of windows...... resulted in a window with a positive net energy gain (in short the Net Gain Window), which means that it contributes to the space heating of the building. All improvements are based on existing technology and manufacturing methods. The results from this work show that the energy performances of windows can...

  8. Windows with an improved energy balance of 30%

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe

    in the guarded hotbox facility at the institute and a total U-value of about 1.2 W/(m2 K) have been measured, which is a reduction compared with the reference window of 0.2 W/(m2 K). The improvements have primarily been obtained by replacing parts of the frame construction with polystyrene foam insulation. Other....... The transparent area forms about 68% of the total window area and the total U-value of the window is about 1.4 W/(m2 K).The energy balance depends strongly of the window orientation and the thermal mass of the room behind. In order to characterize the energy balance of a window with a single value a method has...... been developed, which combines the results from several different building types and building orientations. The energy balance of the reference window has been calculated to -50 kWh/m2 window area, i.e. the refence window accounts for a net energy consumption for space heating of 50 kWh/m2 window area...

  9. Vacuum window glazings for energy-efficient buildings

    Energy Technology Data Exchange (ETDEWEB)

    Benson, D.K.; Smith, L.K.; Tracy, C.E.; Potter, T.; Christensen, C. (Solar Energy Research Inst., Golden, CO (USA)); Soule, D.E. (Western Illinois Univ., Macomb, IL (USA))

    1990-05-01

    The technical feasibility of a patented, laser-welded, evacuated insulating window was studied. The window has two edge-sealed sheets of glass separated by 0.5-mm glass spheres spaced 30 mm apart in a regular array. A highly insulating frame is required and several designs were analyzed. The vacuum window's combination of high solar transmittance and low thermal conductance makes it superior to many other windows in cold climates. In the US Pacific Northwest, the vacuum window could save about 6 MJ of heating energy annually per square meter of window in comparison to conventional, double-glazed windows. A large, vacuum laser-welding facility was designed and installed to conduct glass welding experiments and to fabricate full-sized vacuum windows. Experiments confirmed the feasibility of laser-sealing glass in vacuum but identified two difficulties. Under some circumstances, bubbles of dissolved gases form during welding and weaken the seal. Glass also vaporizes and contaminates the laser beam steering mirror. A novel moving metal foil mirror was developed to circumvent the contamination problem, but it has not yet been used to complete welding experiments and fabricate full-sized vacuum windows. 63 refs., 53 figs., 19 tabs.

  10. Windows CE自定制Shell%Customizing Windows CE Shell

    Institute of Scientific and Technical Information of China (English)

    覃朗; 雷跃明

    2010-01-01

    Shell是用户访问操作系统的接口.Shell开发在Windows CE操作系统开发中占据一定的重要性.对Windows CE Shell进行了概述,并通过建立Shell模型,讲述如何自定制Windows CE Shell和定制Shell必须注意的问题,对Windows CE Shell的定制进行深入研究.

  11. Occupants' window opening behaviour

    DEFF Research Database (Denmark)

    Fabi, Valentina; Andersen, Rune Korsholm; Corgnati, Stefano

    2012-01-01

    Energy consumption in buildings is influenced by several factors related to the building properties and the building controls, some of them highly connected to the behaviour of their occupants.In this paper, a definition of items referring to occupant behaviour related to the building control...... systems is proposed, based on studies presented in literature and a general process leading to the effects on energy consumptions is identified.Existing studies on the topic of window opening behaviour are highlighted and a theoretical framework to deal with occupants' interactions with building controls......, aimed at improving or maintaining the preferred indoor environmental conditions, is elaborated. This approach is used to look into the drivers for the actions taken by the occupants (windows opening and closing) and to investigate the existing models in literature of these actions for both residential...

  12. Process window metrology

    Science.gov (United States)

    Ausschnitt, Christopher P.; Chu, William; Hadel, Linda M.; Ho, Hok; Talvi, Peter

    2000-06-01

    This paper is the third of a series that defines a new approach to in-line lithography control. The first paper described the use of optically measurable line-shortening targets to enhance signal-to-noise and reduce measurement time. The second described the dual-tone optical critical dimension (OCD) measurement and analysis necessary to distinguish dose and defocus. Here we describe the marriage of dual-tone OCD to SEM-CD metrology that comprises what we call 'process window metrology' (PWM), the means to locate each measured site in dose and focus space relative to the allowed process window. PWM provides in-line process tracking and control essential to the successful implementation of low-k lithography.

  13. Duplication of Windows Services

    OpenAIRE

    Shan, Zhiyong; Chiueh, Tzi-cker; Wang, Xin

    2016-01-01

    OS-level virtualization techniques virtualize system resources at the system call interface, has the distinct advantage of smaller run-time resource requirements as compared to HAL-level virtualization techniques, and thus forms an important building block for virtualizing parallel and distributed applications such as a HPC clusters. Because the Windows operating system puts certain critical functionalities in privileged user-level system service processes, a complete OS-level virtualization ...

  14. Target Window Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Woloshun, Keith Albert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-11

    The target window design implemented and tested in experiments at ANL have performed without failure for the available beam of 6 mm FWHM on a 12 mm diameter target. However, scaling that design to a 25 mm diameter target size for a 12 mm FWHM beam has proven problematic. Combined thermal and mechanical (pressure induced) stresses and strains are too high to maintain the small coolant gaps and provide adequate fatigue lifetime.

  15. Windows with improved energy performances

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2003-01-01

    Heat loss through windows represents a considerable part of the total heat loss from houses. However, apart from providing daylight access and view, windows offer a unique potential for solar gain to be exploited during the heating season. Until now valuation of the energy performance of windows...... has primary focused on the heat loss coefficient, U-value. However, as the U-value, especially for the glazing part, has improved considerably during the last years, the total solar energy transmittance, g-value, has become equally important to the total energy performance of windows. Improved energy...... performance of windows can be reached by development of each element of the window, but to gain a considerable improvement in the overall energy performance all elements of the windows need to be examined together and the construction optimised. This paper describes potential improvements of window elements...

  16. Membrane deformation and scission by the HSV-1 nuclear egress complex

    Science.gov (United States)

    Bigalke, Janna M.; Heuser, Thomas; Nicastro, Daniela; Heldwein, Ekaterina E.

    2014-06-01

    The nuclear egress complex (NEC) of herpesviruses such as HSV-1 is essential for the exit of nascent capsids from the cell nucleus. The NEC drives nuclear envelope vesiculation in cells, but the precise budding mechanism and the potential involvement of cellular proteins are unclear. Here we report that HSV-1 NEC alone is sufficient for membrane budding in vitro and thus represents a complete membrane deformation and scission machinery. It forms ordered coats on the inner surface of the budded vesicles, suggesting that it mediates scission by scaffolding the membrane bud and constricting the neck to the point of scission. The inward topology of NEC-mediated budding in vitro resembles capsid budding into the inner nuclear membrane during HSV-1 infection and nuclear envelope vesiculation in NEC-transfected cells. We propose that the NEC functions as minimal virus-encoded membrane-budding machinery during nuclear egress and does not require additional cellular factors.

  17. STS-26 MS Hilmers during egress training at JSC's MAIL full fuselage trainer

    Science.gov (United States)

    1988-01-01

    STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) David C. Hilmers, wearing a launch and entry suit (LES) and launch and entry helmet (LEH), tries out the new crew escape system (CES) inflated slide during an emergency egress training exercise in JSC's Shuttle Mockup and Integration Laboratory (MAIL) Bldg 9A. Technicians stand on either side of the slide ready to help Hilmers to his feet once he reaches the bottom. Watching from floor level at the far left is astronaut Steven R. Nagel. A second crewmember stands in the open side hatch of the Full Fuselage Trainer (FFT) awaiting his turn to slide to 'safety'. During Crew Station Review (CSR) #3, the crew donned the new (navy blue) partial pressure suits (LESs) and checked out CES slide and other CES configurations to evaluate crew equipment and procedures related to emergency egress methods and proposed crew escape options. The CES pole extends out the side hatch just above Hilmers' head.

  18. STS-26 Pilot Covey during egress training at JSC's MAIL full fuselage trainer

    Science.gov (United States)

    1988-01-01

    STS-26 Discovery, Orbiter Vehicle (OV) 103, Pilot Richard O. Covey, wearing a launch and entry suit (LES) and launch and entry helmet (LEH), slides to safety using the new crew escape system (CES) inflated slide during an emergency egress training exercise in JSC's Shuttle Mockup and Integration Laboratory (MAIL) Bldg 9A. Technicians stand on either side of the slide ready to help Covey to his feet once he reaches the bottom. The CES pole extends out the open side hatch of the Full Fuselage Trainer (FFT). During Crew Station Review (CSR) #3, the crew donned the new (navy blue) partial pressure suits (LESs) and checked out CES slide and other CES configurations to evaluate crew equipment and procedures related to emergency egress methods and proposed crew escape options.

  19. Equal access – equal egress: Accounting for people with disabilities in emergency situations

    DEFF Research Database (Denmark)

    Sørensen, Janne Gress; Dederichs, Anne

    2013-01-01

    Accessibility to buildings for all persons independent of their (dis-)abilities is required by law in many countries (the Swedish BBR 3, the Danish BR10:3:2 ). However, accessible buildings are not automatically egressible in case of a fire. The fire safety design is based on escape routes......, and numerical evacuation models are applied for the prediction of the evacuation process in the fire safety design. In many cases these models are best fit to describe a normative description of the population comprehending young abled bodied adults. It has been shown, that some models poorly describe...... (Papaioannou, 2006). It is essential to use models, enabling the prediction of the egress of a total population in a building. In the current quantitative and qualitative study evacuation times and -characteristics from a train in a tunnel are measured for a full-scale evacuation exercise. The results...

  20. Pedestrian dynamics with explicit sharing of exit choice during egress through a long corridor

    Science.gov (United States)

    Srinivasan, Aravinda Ramakrishnan; Karan, Farshad Salimi Naneh; Chakraborty, Subhadeep

    2017-02-01

    The egress literature abounds with studies and models of emergency pedestrian evacuation behavior. Each model tries to incorporate more details and features of the crowd movement dynamics to improve its accuracy. This paper combines a relatively simple pedestrian motion model with a position dependent Voter model to study the effects of opinion sharing on crowd evacuation characteristics. Effect of the presence of leaders on the final outcome of the evacuation is studied in detail. An analytical solution for a simplified version of the egress dynamics with opinion exchange is presented, followed by a set of numerical simulations. Interesting findings about the effect of the strength of interaction between individuals, number and distribution of leaders and initial bias of the evacuees on the final distribution of evacuees over available exits, mean number of steps to evacuate, etc. are presented.

  1. HSV-1 nucleocapsid egress mediated by UL31 in association with UL34 is impeded by cellular transmembrane protein 140

    Energy Technology Data Exchange (ETDEWEB)

    Guan, Ying [Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medicine Science, Peking Union Medical College, Kunming 650118 (China); Yunnan Academy of Tobacco Science, Kunming, Yunnan 650106 (China); Guo, Lei; Yang, Erxia; Liao, Yun; Liu, Longding; Che, Yanchun; Zhang, Ying; Wang, Lichun; Wang, Jingjing [Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medicine Science, Peking Union Medical College, Kunming 650118 (China); Li, Qihan, E-mail: imbcams.lq@gmail.com [Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medicine Science, Peking Union Medical College, Kunming 650118 (China)

    2014-09-15

    During HSV-1 infection, the viral UL31 protein forms a complex with the UL34 protein at the cellular nuclear membrane, where both proteins play important roles in the envelopment of viral nucleocapsids and their egress into the cytoplasm. To characterize the mechanism of HSV-1 nucleocapsid egress, we screened host proteins to identify proteins that interacted with UL31 via yeast two-hybrid analysis. Transmembrane protein 140 (TMEM140), was identified and confirmed to bind to and co-localize with UL31 during viral infection. Further studies indicated that TMEM140 inhibits HSV-1 proliferation through selectively blocking viral nucleocapsid egress during the viral assembly process. The blockage function of TMEM140 is mediated by impeding the formation of the UL31–UL34 complex due to competitive binding to UL31. Collectively, these data suggest the essentiality of the UL31–UL34 interaction in the viral nucleocapsid egress process and provide a new anti-HSV-1 strategy in viral assembly process of nucleocapsid egress. - Highlights: • Cellular TMEM140 protein interacts with HSV-1 UL31 protein during viral infection. • Increasing expression of TMEM140 leads to inhibition of HSV-1 proliferation. • Increasing expression of TMEM140 blocks HSV-1 nucleocapsid egress process. • Binding to UL31 of TMEM140 impedes formation of HSV-1 UL31–UL34 complex.

  2. Mobilní platforma Windows

    OpenAIRE

    Ženíšek, Jan

    2011-01-01

    This bachelor thesis describes to mobile operating system Windows Phone 8. That was introduced in half of the year 2012. The main aim this thesis is to introduce operating system Windows Phone 8. It includes all its parameters, features and technologies, which are necessary for future application development. Partial goal is to explain the possibilities and processes of the development not only for Windows Phone 8 but also for Windows 8. Another crucial goal is the illustrative example of usi...

  3. STS-38 MS Springer climbs through CCT side hatch prior to egress training

    Science.gov (United States)

    1990-01-01

    STS-38 Mission Specialist (MS) Robert C. Springer, wearing launch and entry suit (LES), climbs through the side hatch of the crew compartment trainer (CCT) located in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9A. Springer will practice emergency egress through the side hatch using the crew escape system (CES) pole (at Springer's left). The inflated safety cushion under Springer will break his fall as he rolls out of the side hatch.

  4. STS-47 Astronaut Crew at Pad B for TCDT, Emergency Egress Training, and Photo Opportunity

    Science.gov (United States)

    1992-01-01

    The crew of STS-47, Commander Robert L. Gibson, Pilot Curtis L. Brown, Payload Commander Mark C. Lee, Mission Specialists N. Jan Davis, Jay Apt, and Mae C. Jemison, and Payload Specialist Mamoru Mohri are seen during emergency egress training. Then Commander Gibson introduces the members of the crew and they each give a brief statement about the mission and answer questions from the press.

  5. Cellular mechanisms of alpha herpesvirus egress: live cell fluorescence microscopy of pseudorabies virus exocytosis.

    Directory of Open Access Journals (Sweden)

    Ian B Hogue

    2014-12-01

    Full Text Available Egress of newly assembled herpesvirus particles from infected cells is a highly dynamic process involving the host secretory pathway working in concert with viral components. To elucidate the location, dynamics, and molecular mechanisms of alpha herpesvirus egress, we developed a live-cell fluorescence microscopy method to visualize the final transport and exocytosis of pseudorabies virus (PRV particles in non-polarized epithelial cells. This method is based on total internal reflection fluorescence (TIRF microscopy to selectively image fluorescent virus particles near the plasma membrane, and takes advantage of a virus-encoded pH-sensitive probe to visualize the precise moment and location of particle exocytosis. We performed single-particle tracking and mean squared displacement analysis to characterize particle motion, and imaged a panel of cellular proteins to identify those spatially and dynamically associated with viral exocytosis. Based on our data, individual virus particles travel to the plasma membrane inside small, acidified secretory vesicles. Rab GTPases, Rab6a, Rab8a, and Rab11a, key regulators of the plasma membrane-directed secretory pathway, are present on the virus secretory vesicle. These vesicles undergo fast, directional transport directly to the site of exocytosis, which is most frequently near patches of LL5β, part of a complex that anchors microtubules to the plasma membrane. Vesicles are tightly docked at the site of exocytosis for several seconds, and membrane fusion occurs, displacing the virion a small distance across the plasma membrane. After exocytosis, particles remain tightly confined on the outer cell surface. Based on recent reports in the cell biological and alpha herpesvirus literature, combined with our spatial and dynamic data on viral egress, we propose an integrated model that links together the intracellular transport pathways and exocytosis mechanisms that mediate alpha herpesvirus egress.

  6. Pentagalloylglucose Blocks the Nuclear Transport and the Process of Nucleocapsid Egress to Inhibit HSV-1 Infection.

    Science.gov (United States)

    Jin, Fujun; Ma, Kaiqi; Chen, Maoyun; Zou, Muping; Wu, Yanting; Li, Feng; Wang, Yifei

    2016-01-01

    Herpes simplex virus type 1 (HSV-1), a widespread virus, causes a variety of human viral diseases worldwide. The serious threat of drug-resistance highlights the extreme urgency to develop novel antiviral drugs with different mechanisms of action. Pentagalloylglucose (PGG) is a natural polyphenolic compound with significant anti-HSV activity; however, the mechanisms underlying its antiviral activity need to be defined by further studies. In this study, we found that PGG treatment delays the nuclear transport process of HSV-1 particles by inhibiting the upregulation of dynein (a cellular major motor protein) induced by HSV-1 infection. Furthermore, PGG treatment affects the nucleocapsid egress of HSV-1 by inhibiting the expression and disrupting the cellular localization of pEGFP-UL31 and pEGFP-UL34, which are indispensable for HSV-1 nucleocapsid egress from the nucleus. However, the over-expression of pEGFP-UL31 and pEGFP-UL34 could decrease the antiviral effect of PGG. In this study, for the first time, the antiviral activity of PGG against acyclovir-resistant virus was demonstrated in vitro, and the possible mechanisms of its anti-HSV activities were identified based on the inhibition of nuclear transport and nucleocapsid egress in HSV-1. It was further confirmed that PGG could be a promising candidate for HSV therapy, especially for drug-resistant strains.

  7. Roles of proteases during invasion and egress by Plasmodium and Toxoplasma.

    Science.gov (United States)

    Dowse, Timothy J; Koussis, Konstantinos; Blackman, Michael J; Soldati-Favre, Dominique

    2008-01-01

    Apicomplexan pathogens replicate exclusively within the confines of a host cell. Entry into (invasion) and exit from (egress) these cells requires an array of specialized parasite molecules, many of which have long been considered to have potential as targets of drug or vaccine-based therapies. In this chapter the authors discuss the current state of knowledge regarding the role of parasite proteolytic enzymes in these critical steps in the life cycle of two clinically important apicomplexan genera, Plasmodium and Toxoplasma. At least three distinct proteases of the cysteine mechanistic class have been implicated in egress of the malaria parasite from cells of its vertebrate and insect host. In contrast, the bulk of the evidence indicates a prime role for serine proteases of the subtilisin and rhomboid families in invasion by both parasites. Whereas proteases involved in egress may function predominantly to degrade host cell structures, proteases involved in invasion probably act primarily as maturases and 'sheddases', required to activate and ultimately remove ligands involved in interactions with the host cell.

  8. Teach yourself visually Windows 10

    CERN Document Server

    McFedries, Paul

    2015-01-01

    Learn Windows 10 visually with step-by-step instructions Teach Yourself VISUALLY Windows 10 is the visual learner's guide to the latest Windows upgrade. Completely updated to cover all the latest features, this book walks you step-by-step through over 150 essential Windows tasks. Using full color screen shots and clear instruction, you'll learn your way around the interface, set up user accounts, play media files, download photos from your camera, go online, set up email, and much more. You'll even learn how to customize Windows 10 to suit the way you work best, troubleshoot and repair common

  9. Beginner's guide to Windows 7

    CERN Document Server

    Holden, Susan

    2011-01-01

    This concise, accessible and down-to-earth guide will help you get the most out of your computer using Windows 7, whether you're a complete beginner or upgrading from previous Microsoft operating systems. You'll learn about exciting new features of Windows 7, including how to work with Windows 7 Libraries, how to communicate using Windows Live Mail, how to use Windows Live Photo Gallery, how to browse and search the web using Internet Explorer, and Version 8 and Accelerators.

  10. Windows Home Server users guide

    CERN Document Server

    Edney, Andrew

    2008-01-01

    Windows Home Server brings the idea of centralized storage, backup and computer management out of the enterprise and into the home. Windows Home Server is built for people with multiple computers at home and helps to synchronize them, keep them updated, stream media between them, and back them up centrally. Built on a similar foundation as the Microsoft server operating products, it's essentially Small Business Server for the home.This book details how to install, configure, and use Windows Home Server and explains how to connect to and manage different clients such as Windows XP, Windows Vist

  11. Windows 8.1 simplified

    CERN Document Server

    McFedries, Paul

    2013-01-01

    The easiest way for visual learners to get started with Windows 8 The popular Simplified series makes visual learning easier than ever, and with more than 400,000 copies sold, previous Windows editions are among the bestselling Visual books. Using a Visual approach, this book covers the new features of Windows 8.1 and provides step-by-step instructions for readers who are entirely new to the subject. Inside, you'll discover tasks on topics such as: Windows basics, creating movies, sharing their computer, working with and managing files, browsing the web, and new ways to customize Windows to w

  12. Sunlight Responsive Thermochromic Window System

    Energy Technology Data Exchange (ETDEWEB)

    Millett, F,A; Byker,H, J

    2006-10-27

    Pleotint has embarked on a novel approach with our Sunlight Responsive Thermochromic, SRT™, windows. We are integrating dynamic sunlight control, high insulation values and low solar heat gain together in a high performance window. The Pleotint SRT window is dynamic because it reversibly changes light transmission based on thermochromics activated directly by the heating effect of sunlight. We can achieve a window package with low solar heat gain coefficient (SHGC), a low U value and high insulation. At the same time our windows provide good daylighting. Our innovative window design offers architects and building designers the opportunity to choose their desired energy performance, excellent sound reduction, external pane can be self-cleaning, or a resistance to wind load, blasts, bullets or hurricanes. SRT windows would provide energy savings that are estimated at up to 30% over traditional window systems. Glass fabricators will be able to use existing equipment to make the SRT window while adding value and flexibility to the basic design. Glazing installers will have the ability to fit the windows with traditional methods without wires, power supplies and controllers. SRT windows can be retrofit into existing buildings,

  13. Windows Azure web sites

    CERN Document Server

    Chambers, James

    2013-01-01

    A no-nonsense guide to maintaining websites in Windows Azure If you're looking for a straightforward, practical guide to get Azure websites up and running, then this is the book for you. This to-the-point guide provides you with the tools you need to move and maintain a website in the cloud. You'll discover the features that most affect developers and learn how they can be leveraged to work to your advantage. Accompanying projects enhance your learning experience and help you to walk away with a thorough understanding of Azure's supported technologies, site deployment, and manageme

  14. Transparent aerogel Windows

    DEFF Research Database (Denmark)

    Jensen, Karsten Ingerslev; Schultz, Jørgen Munthe

    In a recent EU FP5 project, monolithic silica aerogel was further developed with respect to the production process at pilot-scale, its properties and the application as transparent insulation material in highly insulating and transparent windows. The aerogel production process has been optimised...... the supercritical washing step included in the drying phase. At the same time the production plant have been modified to recycle most of the chemicals involved in the production process. A large number of aerogel glazing prototypes have been made with partly evacuated aerogel in between two layers of low iron...

  15. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  16. Laplacian magic windows

    Science.gov (United States)

    Berry, M. V.

    2017-06-01

    A transparent sheet, flat to unaided vision but with a gentle surface relief, can concentrate light onto a screen with intensity reproducing any desired image: the sheet is a ‘magic window’. When the ray deflections are sufficiently small that there are no caustics between the window and the screen, the image intensity is the Laplacian function of the relief height function—a very simple approximation to general freeform optics. Therefore the desired relief is obtained by solving Poisson’s equation. Numerical simulations indicate that the Laplacian image approximation will apply to realistic situations.

  17. SAF for Windows

    DEFF Research Database (Denmark)

    Hansen, Timme

    2001-01-01

    SAF for Windows er et computerprogram til parametrisk konstruktion af translationsskaller. Skaloverfladernes tredimensionelle, facetterede form fremkommer ved en kombination af to todimensionelle formbestemmende kurver, som kan vælges og redigeres af brugeren. Programmet kan udfolde de genererede...... skaller, så facetternes sande størrelse vises, og danne en liste med alle mål. Både skallernes tredimensionelle og todimensionelle form kan eksporteres som DXF-filer til CAD programmer. Programmet indeholder stadig fejl - jeg arbejder på en ny version....

  18. Radiation controlling reversible window

    Energy Technology Data Exchange (ETDEWEB)

    Gell, H.A. Jr.

    1980-01-01

    A coated glass glazing system is presented including a transparent glass substrate having one surface coated with a radiation absorptive film which is overcoated with a radiation reflective film by a technique which renders the radiation reflective film radiation absorptive at the surface contracting the radiating absorptive film. The coated glass system is used as glazing for storm windows which are adapted to be reversible so that the radiation reflective surface may be exposed to the outside of the dwelling during the warm seasons to prevent excessive solar radiation from entering a dwelling and reversed during cold seasons to absorb solar radiation and utilize it to aid in keeping the dwelling interior warm.

  19. Invariant sets for Windows

    CERN Document Server

    Morozov, Albert D; Dragunov, Timothy N; Malysheva, Olga V

    1999-01-01

    This book deals with the visualization and exploration of invariant sets (fractals, strange attractors, resonance structures, patterns etc.) for various kinds of nonlinear dynamical systems. The authors have created a special Windows 95 application called WInSet, which allows one to visualize the invariant sets. A WInSet installation disk is enclosed with the book.The book consists of two parts. Part I contains a description of WInSet and a list of the built-in invariant sets which can be plotted using the program. This part is intended for a wide audience with interests ranging from dynamical

  20. Improved Windows for Cold Climates

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2005-01-01

    A large part of the energy consumption in countries in Nordic and Arctic climates is used for space heating in buildings. In typical buildings the windows are responsible for a considerable part of the heat losses. Therefore there is a large potential for energy savings by developing and using...... windows with improved energy performance. Traditionally evaluation of the energy performance of windows has focussed on the thermal transmittance, but as windows differ from the rest of the building envelope by allowing solar energy to enter the building, the total solar energy transmittance is equally...... of the heating demand in typical single-family houses in Denmark and Greenland. The examined windows are typical new windows from Nordic countries and new proposals of improved windows with low thermal transmittance and high total solar energy transmittance. The results show that net energy gain can be increased...

  1. Constraints on Relaxion Windows

    CERN Document Server

    Choi, Kiwoon

    2016-01-01

    We examine low energy phenomenology of the relaxion solution to the weak scale hierarchy problem. Assuming that the Hubble friction is responsible for the dissipation of relaxion energy, we identify the cosmological relaxion window which corresponds to the parameter region compatible with a given value of the acceptable number of inflationary $e$-foldings. We then discuss a variety of observational constraints on the relaxion window, while focusing on the case that the barrier potential to stabilize the relaxion is induced by new physics, rather than by low energy QCD dynamics. We find that majority of the parameter space with a relaxion mass $m_\\phi\\gtrsim 100$ eV or a relaxion decay constant $f\\lesssim 10^7$ GeV is excluded by existing constraints. There is an interesting small parameter region with $m_\\phi\\sim \\,0.2-1$ GeV and $f\\sim\\, {\\rm few}-10$ TeV, which is allowed by existing constraints, but can be probed soon by future beam dump experiment such as the SHiP experiment, or by improved EDM experiment...

  2. WINDOW-CLEANING

    CERN Multimedia

    Environmental Section / ST-TFM

    2001-01-01

    The two-month window-cleaning session on the Meyrin, Prévessin and LEP sites will soon begin. The cleaning contractors will work from Monday to Saturday, every week from 4.00 a.m. to 8.00 p.m. The work will be organised so as to disturb users as little as possible. In any event, a work notice will be left in each office 24 hours beforehand. To prevent any damage to documents or items which could occur despite the precautions taken, please clear completely the window-sills and the area immediately around them. If, however, for valid reasons, the work cannot be done on the scheduled day, please inform the Environmental Section by telephoning: 73753 / 74233 / 72242 If you are going to be absent during this two-month period, we should be grateful if you would clear the above mentioned areas before your departure. REMINDER To allow more thorough cleaning of the entrance doors to buildings and also facilitate the weekly work of the cleaning contractors, we ask you to make use of the notice boards at the...

  3. WINDOW-CLEANING

    CERN Multimedia

    Environmental Section / ST-TFM

    2001-01-01

    The two-month window-cleaning session on the Meyrin, Prévessin and LEP sites will soon begin. The cleaning contractors will work from Monday to Saturday, every week from 4.00 a.m. to 8.00 p.m. The work will be organised so as to disturb users as little as possible. In any event, a work notice will be left in each office 24 hours beforehand. To prevent any damage to documents or items which could occur despite the precautions taken, please clear completely the window-sills and the area immediately around them. If, however, for valid reasons, the work cannot be done on the scheduled day, please inform the Environmental Section by telephoning: 73753 / 74233 / 72242 If you are going to be absent during this two-month period, we should be grateful if you would clear the above mentioned areas before your departure. REMINDER To allow more thorough cleaning of the entrance doors to buildings and also facilitate the weekly work of the cleaning contractors, we ask you to make use of the notice boards at the...

  4. Improved Windows for Cold Climates

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2005-01-01

    A large part of the energy consumption in countries in Nordic and Arctic climates is used for space heating in buildings. In typical buildings the windows are responsible for a con-siderable part of the heat losses. Therefore there is a large potential for energy savings by developing and using...... windows with improved energy performance. Traditionally evaluation of the energy performance of windows has focused on the thermal transmittance, but as windows differ from the rest of the building envelope by allowing solar energy to enter the building, the total solar energy transmittance is equally...... important. In the heating season in cold climates the solar gain through windows can be utilized for space heating which results in a corresponding reduction in the energy production that is often based on fossil fuels. A suitable quantity for evaluating the energy performance of windows in a simple...

  5. Improved Windows for Cold Climates

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2005-01-01

    A large part of the energy consumption in countries in Nordic and Arctic climates is used for space heating in buildings. In typical buildings the windows are responsible for a considerable part of the heat losses. Therefore there is a large potential for energy savings by developing and using...... windows with improved energy performance. Traditionally evaluation of the energy performance of windows has focussed on the thermal transmittance, but as windows differ from the rest of the building envelope by allowing solar energy to enter the building, the total solar energy transmittance is equally...... important. In the heating season in cold climates the solar gain through windows can be utilized for space heating which results in a corresponding reduction in the energy production that is often based on fossil fuels. A suitable quantity for evaluating the energy perform-ance of windows in a simple...

  6. Window observers for linear systems

    Directory of Open Access Journals (Sweden)

    Utkin Vadim

    2000-01-01

    Full Text Available Given a linear system x ˙ = A x + B u with output y = C x and a window function ω ( t , i.e., ∀ t , ω ( t ∈ {0,1 }, and assuming that the window function is Lebesgue measurable, we refer to the following observer, x ˆ = A x + B u + ω ( t L C ( x − x ˆ as a window observer. The stability issue is treated in this paper. It is proven that for linear time-invariant systems, the window observer can be stabilized by an appropriate design under a very mild condition on the window functions, albeit for linear time-varying system, some regularity of the window functions is required to achieve observer designs with the asymptotic stability. The corresponding design methods are developed. An example is included to illustrate the possible applications

  7. Redefining the Axion Window

    Science.gov (United States)

    Di Luzio, Luca; Mescia, Federico; Nardi, Enrico

    2017-01-01

    A major goal of axion searches is to reach inside the parameter space region of realistic axion models. Currently, the boundaries of this region depend on somewhat arbitrary criteria, and it would be desirable to specify them in terms of precise phenomenological requirements. We consider hadronic axion models and classify the representations RQ of the new heavy quarks Q . By requiring that (i) the Q 's are sufficiently short lived to avoid issues with long-lived strongly interacting relics, (ii) no Landau poles are induced below the Planck scale; 15 cases are selected which define a phenomenologically preferred axion window bounded by a maximum (minimum) value of the axion-photon coupling about 2 times (4 times) larger than is commonly assumed. Allowing for more than one RQ, larger couplings, as well as complete axion-photon decoupling, become possible.

  8. Redefining the Axion Window

    CERN Document Server

    Di Luzio, Luca; Nardi, Enrico

    2016-01-01

    A major goal of axion searches is to reach inside the parameter space region of realistic axion models. Currently, the boundaries of this region depend on somewhat arbitrary criteria, and it would be desirable to specify them in terms of precise phenomenological requirements. We consider hadronic axion models and classify the representations $R_Q$ of the new heavy quarks $Q$. By requiring that $i)$ the $Q$ are sufficiently short lived to avoid issues with long lived strongly interacting relics, $ii)$ no Landau poles are induced below the Planck scale, fifteen cases are selected, which define a phenomenologically preferred axion window bounded by a maximum (minimum) value of the axion-photon coupling about twice (four times) larger than commonly assumed. Allowing for more than one $R_Q$, larger couplings, as well as complete axion-photon decoupling, become possible.

  9. Real Clifford Windowed Fourier Transform

    Institute of Scientific and Technical Information of China (English)

    Mawardi BAHRI; Sriwulan ADJI; Ji Man ZHAO

    2011-01-01

    We study the windowed Fourier transform in the framework of Clifford analysis, which we call the Clifford windowed Fourier transform (CWFT). Based on the spectral representation of the Clifford Fourier transform (CFT), we derive several important properties such as shift, modulation,reconstruction formula, orthogonality relation, isometry, and reproducing kernel. We also present an example to show the differences between the classical windowed Fourier transform (WFT) and the CWFT. Finally, as an application we establish a Heisenberg type uncertainty principle for the CWFT.

  10. Windows 7 The Missing Manual

    CERN Document Server

    Pogue, David

    2010-01-01

    In early reviews, geeks raved about Windows 7. But if you're an ordinary mortal, learning what this new system is all about will be challenging. Fear not: David Pogue's Windows 7: The Missing Manual comes to the rescue. Like its predecessors, this book illuminates its subject with reader-friendly insight, plenty of wit, and hardnosed objectivity for beginners as well as veteran PC users. Windows 7 fixes many of Vista's most painful shortcomings. It's speedier, has fewer intrusive and nagging screens, and is more compatible with peripherals. Plus, Windows 7 introduces a slew of new features,

  11. Windows 7 the definitive guide

    CERN Document Server

    Stanek, William R

    2010-01-01

    This book provides everything you need to manage and maintain Windows 7. You'll learn all of the features and enhancements in complete detail, along with specifics for configuring the operating system to put you in full control. Bestselling author and Windows expert William Stanek doesn't just show you the steps you need to follow, he also tells you how features work, why they work, and how you can customize them to meet your needs. Learn how to squeeze every bit of power out of Windows 7 to take full advantage of its features and programs. Set up, customize, and tune Windows 7-Optimize its

  12. 探索Windows2001

    Institute of Scientific and Technical Information of China (English)

    李红

    2000-01-01

    Window S2000刚刚发布,微软就在开发其后继产品WindowS2001(产品代号Whistler),Windows 2001就是传说中的Windows Whistler,微软在.net计划中称之为“下个版本的Windows”,它将是第一个同时包含消费型和商业型操作系统代码的Windows,采用基于XML的全新用户界面(被称作“视觉风格”)。

  13. Microsoft Windows Operating System Essentials

    CERN Document Server

    Carpenter, Tom

    2012-01-01

    A full-color guide to key Windows 7 administration concepts and topics Windows 7 is the leading desktop software, yet it can be a difficult concept to grasp, especially for those new to the field of IT. Microsoft Windows Operating System Essentials is an ideal resource for anyone new to computer administration and looking for a career in computers. Delving into areas such as fundamental Windows 7 administration concepts and various desktop OS topics, this full-color book addresses the skills necessary for individuals looking to break into a career in IT. Each chapter begins with a list of topi

  14. Subject Responses to Electrochromic Windows

    Energy Technology Data Exchange (ETDEWEB)

    Clear, Robert; Inkarojrit, Vorapat; Lee, Eleanor

    2006-03-03

    Forty-three subjects worked in a private office with switchable electrochromic windows, manually-operated Venetian blinds, and dimmable fluorescent lights. The electrochromic window had a visible transmittance range of approximately 3-60%. Analysis of subject responses and physical data collected during the work sessions showed that the electrochromic windows reduced the incidence of glare compared to working under a fixed transmittance (60%) condition. Subjects used the Venetian blinds less often and preferred the variable transmittance condition, but used slightly more electric lighting with it than they did when window transmittance was fixed.

  15. Beginning Windows 8.1

    CERN Document Server

    Halsey, Mike

    2013-01-01

    Windows 8 has been described by Microsoft as its 'boldest' Windows release ever and the 8.1 update enhances the paradigm further. Beginning Windows 8.1 takes you through the new features and helps you get more out of the familiar to reveal the fullest possibilities for this amazing new operating system. You will learn, with non-technical language used throughout, how to get up and running in the new Windows interface, minimize downtime, maximize productivity, and harness the features you never knew existed to take control of your computer and enjoy the peace of mind and excitement that comes w

  16. Development of Countermeasures to Aid Functional Egress from the Crew Exploration Vehicle Following Long Duration Spaceflight

    Science.gov (United States)

    Mulavara, Ajitkumar; Fiedler, Matthew; Kofman, Igor; Fisher, Elizabeth; Wood, Scott; Serrador, Jorge; Peters, Brian; Cohen, Helen; Reschke, Millard; Bloomberg, Jacob

    2009-01-01

    Astronauts experience disturbances in sensorimotor function following their return to Earth due to adaptive responses that occur during exposure to the microgravity conditions of space flight. As part of the Crew Exploration Vehicle design requirements, the crewmember adapted to the microgravity state may need to egress the vehicle within a few minutes for safety and operational reasons in various sea state conditions following a water landing. The act of emergency egress includes and is not limited to rapid motor control tasks (including both fine motor such as object manipulation and gross motor such as opening a hatch) and visual acuity tasks while maintaining spatial orientation and postural stability in time to escape safely. Exposure to even low frequency motions (0.2-2.0 Hz) induced by sea conditions surrounding a vessel can cause significant fine and gross motor control problems affecting critical functions. These motion frequencies coupled with the varying sea state conditions (frequencies ranging from 0.125-0.5 Hz) cause performance deficits by affecting the efficacy of motor and visual acuity dependent skills in tasks critical to emergency egress activities such as visual monitoring of displays, actuating discrete controls, operating auxiliary equipment and communicating with Mission Control and recovery teams. Thus, during exploration class missions the sensorimotor disturbances due to the crewmember's adaptation to microgravity may lead to disruption in the ability to maintain postural stability and perform functional egress tasks during the initial introduction to the Earth's gravitational environment. At present, the functional implication of the interactions between a debilitated crewmember during readaptation to Earth s gravity and the environmental constraints imposed by a water landing scenario is not defined and no operational countermeasure has been implemented to mitigate this risk. Stochastic resonance (SR) is a mechanism whereby noise can

  17. TgCDPK3 Regulates Calcium-Dependent Egress of Toxoplasma gondii from Host Cells

    Science.gov (United States)

    McCoy, James M.; Whitehead, Lachlan; van Dooren, Giel G.; Tonkin, Christopher J.

    2012-01-01

    The phylum Apicomplexa comprises a group of obligate intracellular parasites of broad medical and agricultural significance, including Toxoplasma gondii and the malaria-causing Plasmodium spp. Key to their parasitic lifestyle is the need to egress from an infected cell, actively move through tissue, and reinvade another cell, thus perpetuating infection. Ca2+-mediated signaling events modulate key steps required for host cell egress, invasion and motility, including secretion of microneme organelles and activation of the force-generating actomyosin-based motor. Here we show that a plant-like Calcium-Dependent Protein Kinase (CDPK) in T. gondii, TgCDPK3, which localizes to the inner side of the plasma membrane, is not essential to the parasite but is required for optimal in vitro growth. We demonstrate that TgCDPK3, the orthologue of Plasmodium PfCDPK1, regulates Ca2+ ionophore- and DTT-induced host cell egress, but not motility or invasion. Furthermore, we show that targeting to the inner side of the plasma membrane by dual acylation is required for its activity. Interestingly, TgCDPK3 regulates microneme secretion when parasites are intracellular but not extracellular. Indeed, the requirement for TgCDPK3 is most likely determined by the high K+ concentration of the host cell. Our results therefore suggest that TgCDPK3's role differs from that previously hypothesized, and rather support a model where this kinase plays a role in rapidly responding to Ca2+ signaling in specific ionic environments to upregulate multiple processes required for gliding motility. PMID:23226109

  18. Windows forensic analysis toolkit advanced analysis techniques for Windows 7

    CERN Document Server

    Carvey, Harlan

    2012-01-01

    Now in its third edition, Harlan Carvey has updated "Windows Forensic Analysis Toolkit" to cover Windows 7 systems. The primary focus of this edition is on analyzing Windows 7 systems and on processes using free and open-source tools. The book covers live response, file analysis, malware detection, timeline, and much more. The author presents real-life experiences from the trenches, making the material realistic and showing the why behind the how. New to this edition, the companion and toolkit materials are now hosted online. This material consists of electronic printable checklists, cheat sheets, free custom tools, and walk-through demos. This edition complements "Windows Forensic Analysis Toolkit, 2nd Edition", (ISBN: 9781597494229), which focuses primarily on XP. It includes complete coverage and examples on Windows 7 systems. It contains Lessons from the Field, Case Studies, and War Stories. It features companion online material, including electronic printable checklists, cheat sheets, free custom tools, ...

  19. STS-35 Pilot Gardner and MS Hoffman during egress training at JSC

    Science.gov (United States)

    1990-01-01

    STS-35 Pilot Guy S. Gardner (standing) and Mission Specialist (MS) Jeffrey A. Hoffman prepare for egress training at JSC's Mockup and Integration Laboratory (MAIL) Bldg 9A. Gardner and Hoffman, wearing orange launch and entry suits (LESs), adjust their parachute harnesses as they listen to instructions before training begins. The astronaut crewmembers and payload specialists for the scheduled May flight were specifically learning proper measures to take in the event of an emergency on the launch pad necessitating emergency evacuation of the orbiter.

  20. Learning Windows Azure Mobile Services for Windows 8 and Windows Phone 8

    CERN Document Server

    Webber-Cross, Geoff

    2014-01-01

    This book is based around a case study game which was written for the book. This means that the chapters progress in a logical way and build upon lessons learned as we go. Real-world examples are provided for each topic that are practical and not given out-of-context so they can be applied directly to other applications.If you are a developer who wishes to build Windows 8 and Phone 8 applications and integrate them with Windows Azure Mobile Services, this book is for you. Basic C# and JavaScript skills are advantageous, as well as some knowledge of building Windows 8 or Windows Phone 8 applica

  1. Window prototypes during the project

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe

    1996-01-01

    The conditions for the PASSYS test and the results of the measurements on one of the aerogel window prototypes are described.......The conditions for the PASSYS test and the results of the measurements on one of the aerogel window prototypes are described....

  2. Inventions on Displaying and Resizing Windows

    OpenAIRE

    Mishra, Umakant

    2014-01-01

    Windows are used quite frequently in a GUI environment. The greatest advantage of using windows is that each window creates a virtual screen space. Hence, although the physical screen space is limited to a few inches, use of windows can create unlimited screen space to display innumerable items. The use of windows facilitates the user to open and interact with multiple programs or documents simultaneously in different windows. Sometimes a single program may also open multiple windows to displ...

  3. The workplace window view

    DEFF Research Database (Denmark)

    Lottrup, Lene Birgitte Poulsen; Stigsdotter, Ulrika K.; Meilby, Henrik

    2015-01-01

    Office workers’ job satisfaction and ability to work are two important factors for the viability and competitiveness of most companies, and existing studies in contexts other than workplaces show relationships between a view of natural elements and, for example, student performance and neighbourh......Office workers’ job satisfaction and ability to work are two important factors for the viability and competitiveness of most companies, and existing studies in contexts other than workplaces show relationships between a view of natural elements and, for example, student performance...... and neighbourhood satisfaction. This study investigates whether relationships between window view, and work ability and job satisfaction also exist in the context of the workplace by focusing on office workers’ view satisfaction. The results showed that a view of natural elements was related to high view...... satisfaction, and that high view satisfaction was related to high work ability and high job satisfaction. Furthermore, the results indicated that job satisfaction mediated the effect of view satisfaction on work ability. These findings show that a view of a green outdoor environment at the workplace can...

  4. Handbook on Windows and Energy

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Schultz, Jørgen Munthe; Svendsen, Sv Aa Højgaard

    The handbook on windows and energy is a general description of windows with the main focus put on the energy performance. Common window products are described by commonly used nomenclature, description of frame and sash conctructions and description of commonly used glazing types.The energy...... flow and detailed calculation of light and solar transmittance is given.Different measurement techniques for characterization of window heat loss coefficient and total solar energy transmittance is described and references to interantional standards are given.Finally, the handbook includes...... a comprehensive list of window related standards and a list of Nordic research and development projects.Two programs are encloased in the handbook for calculation of solar radiation on inclined surfaces including a shadow correction and a simple program for evaluation of energy savings and risk of overtemperature....

  5. Securing Applications in Windows Phone

    Directory of Open Access Journals (Sweden)

    B. Venkat Sandeep

    2012-06-01

    Full Text Available Windows Phone 7 has been planned with speed in mind. Windows phone is the new baby from Microsoft which is impressed by its features. More than 80,000 apps have now been published in the Windows Phone Marketplace and new content is currently being added at the rate of 340 apps per day [1]. Although there are many benefits, these are not without risks. Most of today’s mobile applications are transaction based, the security is even greater. In this paper we will discuss about the security in mobile devices, and how the windows phone has supported in developing secure applications. Also discuss about the isolated storage feature in windows phone. As security is more important for the Mobile devices, this also discusses how the additional security is provided to the apps.

  6. Thermal bridges of modern windows

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place; Møller, Eva B.; Nielsen, Anker

    2013-01-01

    With its focus on reduced energy consumption, contemporary housing construction requires a highly insulated and airtight building envelope with as few thermal bridges as possible.Windows must be carefully designed, as thermal bridges can lead to surface condensation or mold growth, even...... if the window has an U-factor of 1 W/(m2·K) or lower. This paper describes the development of modern, energy efficient Danish windows with reduced thermal bridges. It focuses on materials, geometry, and sealing of window panes based on a literature review. Examples of modern windows are presented. Experience...... with the minimum acceptable surface temperature regarding surface condensation or mold growth, implemented in the Danish Building Regulations in 2010, and the calculation method for this temperature based on international standards is discussed. The introduction of the minimum acceptable surface temperature has...

  7. Improved Windows for Cold Climates

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    2005-01-01

    of the heating demand in typical single-family houses in Denmark and Greenland. The examined windows are typical new windows from Nordic countries and new proposals of improved windows with low thermal transmittance and high total solar energy transmittance. The results show that net energy gain can be increased...... considerably by reducing the frame width, which results in a larger transparent area causing a larger solar gain but still main-taining a low thermal transmittance. Using three layers of glass with large gaps, using very slim frame profiles, and omitting the edge constructions that normally causes thermal...... bridges achieve this. Applying shutters or low emissivity coated roller blinds incorporated in the glazing that are activated during night time can improve the energy performance of windows. The results from this work show that it is possible to develop windows with a positive net energy in a fairly...

  8. Windows for tablets for dummies

    CERN Document Server

    Rathbone, Andy

    2013-01-01

    Just for you--Windows 8 from the tablet user's perspective If you're an experienced Windows user, you don't need a guide to everything that Windows 8 can do, just to those tools and functions that work on your tablet. And so here it is. This new book zeros in on what you need to know to work best on your tablet with Windows 8. Topics include navigating the new Windows 8 interface and how it works on a touchscreen, how to safely connect to the Internet, how to work with apps or share your tablet in a group, and much more. If you're a new tablet user, you'll particularly appre

  9. Prism Window for Optical Alignment

    Science.gov (United States)

    Tang, Hong

    2008-01-01

    A prism window has been devised for use, with an autocollimator, in aligning optical components that are (1) required to be oriented parallel to each other and/or at a specified angle of incidence with respect to a common optical path and (2) mounted at different positions along the common optical path. The prism window can also be used to align a single optical component at a specified angle of incidence. Prism windows could be generally useful for orienting optical components in manufacture of optical instruments. "Prism window" denotes an application-specific unit comprising two beam-splitter windows that are bonded together at an angle chosen to obtain the specified angle of incidence.

  10. Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses.

    Science.gov (United States)

    Bigalke, J M; Heldwein, E E

    2017-01-01

    Herpesviruses are unusual among enveloped viruses because they bud twice yet acquire a single envelope. Furthermore, unlike other DNA viruses that replicate in the nucleus, herpesviruses do not exit it by passing through the nuclear pores or by rupturing the nuclear envelope. Instead, herpesviruses have a complex mechanism of nuclear escape whereby nascent capsids bud at the inner nuclear membrane to form perinuclear virions that subsequently fuse with the outer nuclear membrane, releasing capsids into the cytosol. This makes them some of the very few known viruses that bud into the nuclear envelope. The envelope acquired during nuclear budding does not end up in the mature viral particle but instead allows the capsid to translocate from the nucleus into the cytosol. The viral nuclear egress complex (NEC) is a critical player in the nuclear egress, yet its function and mechanism have remained enigmatic. Recent studies have demonstrated that the NEC buds membranes without the help of other proteins by forming a honeycomb coat, which established the NEC as the first virally encoded budding machine that operates at the nuclear, as opposed to cytoplasmic, membrane. This review discusses our current understanding of the NEC budding mechanism, with the emphasis on studies that illuminated the structure of the NEC coat and its role in capsid budding during herpesvirus nuclear escape.

  11. Effects of bed height on the biomechanics of hospital bed entry and egress.

    Science.gov (United States)

    Merryweather, Andrew S; Morse, Janice M; Doig, Alexa K; Godfrey, Nathan W; Gervais, Pierre; Bloswick, Donald S

    2015-01-01

    Although a significant proportion of patient falls in hospitals occur in the vicinity of the hospital bed, little is known about the contribution of bed height to fall risk. To compare lower extremity joint torques and angles during hospital bed entry and egress at two bed heights. Twelve adults (age > 55) were purposively selected and had variety of strength and mobility limitations. Biomechanical data for this pilot study were collected with three digital video cameras and processed to obtain estimates for joint torques and included angles. At the low bed height, hip torque for bed entry was significantly higher, and hip, knee, and ankle flexion angles were significantly smaller. The absence of significant differences in knee and ankle torques were the result of a compensation strategy that shifts the center of mass forward by flexing the torso during low bed ingress. Torque data from the egress motion were similar, however 50% of participants were unable to rise from the low bed without assistance. Healthcare providers should be aware that low bed heights pose safety risks to the population for which they were designed-elderly persons at high risk for falling.

  12. Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues

    Science.gov (United States)

    Martin, Aaron J.; Clark, Matthew; Gojanovich, Gregory; Manzoor, Fatima; Miller, Keith; Kline, Douglas E.; Morillon, Y. Maurice; Wang, Bo

    2016-01-01

    There continues to be a need for immunotherapies to treat type 1 diabetes in the clinic. We previously reported that nondepleting anti-CD4 and -CD8 Ab treatment effectively reverses diabetes in new-onset NOD mice. A key feature of the induction of remission is the egress of the majority of islet-resident T cells. How this occurs is undefined. Herein, the effects of coreceptor therapy on islet T cell retention were investigated. Bivalent Ab binding to CD4 and CD8 blocked TCR signaling and T cell cytokine production, while indirectly downregulating islet chemokine expression. These processes were required for T cell retention, as ectopic IFN-γ or CXCL10 inhibited Ab-mediated T cell purging. Importantly, treatment of humanized mice with nondepleting anti–human CD4 and CD8 Ab similarly reduced tissue-infiltrating human CD4+ and CD8+ T cells. These findings demonstrate that Ab binding of CD4 and CD8 interrupts a feed-forward circuit by suppressing T cell–produced cytokines needed for expression of chemotactic cues, leading to rapid T cell egress from the islets. Coreceptor therapy therefore offers a robust approach to suppress T cell–mediated pathology by purging T cells in an inflammation-dependent manner.

  13. Conformal ALON® and spinel windows

    Science.gov (United States)

    Goldman, Lee M.; Smith, Mark; Ramisetty, Mohan; Jha, Santosh; Sastri, Suri

    2017-05-01

    The requirements for modern aircraft based reconnaissance systems are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the ability to produce windows in complex geometries currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows. ALON consists primarily of aluminum and oxygen, similar to that of alumina, with a small amount of nitrogen added to help stabilize the cubic gamma-AlON phase. ALON's chemical similarity to alumina, translates into a robust manufacturing process. This ease of processing has allowed Surmet to produce ALON windows and domes in a wide variety of geometries and sizes. Spinel (MgAl2O4) contains equal molar amounts of MgO and Al2O3, and is a cubic material, that transmits further into the Infrared than ALON. Spinel is produced via powder processing techniques similar to those used to produce ALON. Surmet is now applying the lessons learned with ALON to produce conformal spinel windows and domes as well.

  14. Windows 8 visual quick tips

    CERN Document Server

    McFedries, Paul

    2012-01-01

    Easy-in, easy-out format covers all the bells and whistles of Windows 8 If you want to learn how to work smarter and faster in Microsoft's Windows 8 operating system, this easy-to-use, compact guide delivers the goods. Designed for visual learners, it features short explanations and full-color screen shots on almost every page, and it's packed with timesaving tips and helpful productivity tricks. From enhancing performance and managing digital content to setting up security and much more, this handy guide will help you get more out of Windows 8. Uses full-color screen shots and short, step-by-

  15. Windows Phone 7 Made Simple

    CERN Document Server

    Trautschold, Martin

    2011-01-01

    With Windows Phone 7, Microsoft has created a completely new smartphone operating system that focuses on allowing users to be productive with their smartphone in new ways, while offering seamless integration and use of Microsoft Office Mobile as well as other productivity apps available in the Microsoft App Store. Windows Phone 7 Made Simple offers a clear, visual, step-by-step approach to using your Windows Phone 7 smartphone, no matter what the manufacturer. Author Jon Westfall is an expert in mobile devices, recognized by Microsoft as a "Most Valuable Professional" with experience

  16. Grab Windows training opportunities; check CERN Windows roadmap!

    CERN Multimedia

    IT Department

    2011-01-01

    CERN Operating Systems and Information Services group (IT-OIS) actively monitors market trends to check how new software products correspond to CERN needs. In the Windows world, Windows 7 has been a big hit, with over 1500 Windows 7 PCs within less than a year since its support was introduced at CERN. No wonder: Windows XP is nearly 10 years old and is steadily approaching the end of its life-cycle. At CERN, support for Windows XP will stop at the end of December 2012. Compared to Vista, Windows 7 has the same basic hardware requirements, but offers higher performance, so the decision to upgrade is rather straightforward. CERN support for Vista will end in June 2011. In the world of Microsoft Office, version 2007 offers better integration with the central services than the older version 2003. Progressive upgrade from 2003 to 2007 is planned to finish in September 2011, but users are encouraged to pro-actively upgrade at their convenience. Please note that Office 2007 brings an important change in the area of ...

  17. Three-dimensional laser window formation for industrial application

    Science.gov (United States)

    Verhoff, Vincent G.; Kowalski, David

    1993-01-01

    The NASA Lewis Research Center has developed and implemented a unique process for forming flawless three-dimensional, compound-curvature laser windows to extreme accuracies. These windows represent an integral component of specialized nonintrusive laser data acquisition systems that are used in a variety of compressor and turbine research testing facilities. These windows are molded to the flow surface profile of turbine and compressor casings and are required to withstand extremely high pressures and temperatures. This method of glass formation could also be used to form compound-curvature mirrors that would require little polishing and for a variety of industrial applications, including research view ports for testing devices and view ports for factory machines with compound-curvature casings. Currently, sodium-alumino-silicate glass is recommended for three-dimensional laser windows because of its high strength due to chemical strengthening and its optical clarity. This paper discusses the main aspects of three-dimensional laser window formation. It focuses on the unique methodology and the peculiarities that are associated with the formation of these windows.

  18. A transparent vacuum window for high-intensity pulsed beams

    CERN Document Server

    Monteil, M; Veness, R

    2011-01-01

    The HiRadMat (High-Radiation to Materials) facility Ill will allow testing of accelerator components, in particular those of the Large Hadron Collider (LHC) at CERN, under the impact of high-intensity pulsed beams. To reach this intensity range, the beam will be focused on a focal point where the target to be tested is located. A 60 mm aperture vacuum window will separate the vacuum of the beam line which is kept under high vacuum 10(-8) mbar, from the test area which is at atmospheric pressure. This window has to resist collapse due to beam passage. The high-intensity of the beam means that typical materials used for standard vacuum windows (such as stainless steel, aluminium and titanium alloy) cannot endure the energy deposition induced by the beam passage. Therefore, a vacuum window has been designed to maintain the differential pressure whilst resisting collapse due to the beam impact on the window. In this paper, we will present calculations of the energy transfer from beam to window, the design of the ...

  19. Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito.

    Science.gov (United States)

    Sologub, Ludmilla; Kuehn, Andrea; Kern, Selina; Przyborski, Jude; Schillig, Rebecca; Pradel, Gabriele

    2011-06-01

    Malaria parasites reside in human erythrocytes within a parasitophorous vacuole. The parasites are transmitted from the human to the mosquito by the uptake of intraerythrocytic gametocytes during a blood meal, which in the midgut become activated by external stimuli and subsequently egress from the enveloping erythrocyte. Gametocyte egress is a crucial step for the parasite to prepare for fertilization, but the molecular mechanisms of egress are not well understood. Via electron microscopy, we show that Plasmodium falciparum gametocytes exit the erythrocyte by an inside-out type of egress. The parasitophorous vacuole membrane (PVM) ruptures at multiple sites within less than a minute following activation, a process that requires a temperature drop and parasite contact with xanthurenic acid. PVM rupture can also be triggered by the ionophore nigericin and is sensitive to the cysteine protease inhibitor E-64d. Following PVM rupture the subpellicular membrane begins to disintegrate. This membrane is specific to malaria gametocytes, and disintegration is impaired by the aspartic protease inhibitor EPNP and the cysteine/serine protease inhibitor TLCK. Approximately 15 min post activation, the erythrocyte membrane ruptures at a single breaking point, which can be inhibited by inhibitors TLCK and TPCK. In all cases inhibitor treatment results in interrupted gametogenesis. © 2011 Blackwell Publishing Ltd.

  20. Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress.

    Directory of Open Access Journals (Sweden)

    Christine R Collins

    2013-05-01

    Full Text Available The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV. Eventually, in a tightly regulated process called egress, proteins of the PV and intracellular merozoite surface are modified by an essential parasite serine protease called PfSUB1, whilst the enclosing PV and erythrocyte membranes rupture, releasing merozoites to invade fresh erythrocytes. Inhibition of the Plasmodium falciparum cGMP-dependent protein kinase (PfPKG prevents egress, but the underlying mechanism is unknown. Here we show that PfPKG activity is required for PfSUB1 discharge into the PV, as well as for release of distinct merozoite organelles called micronemes. Stimulation of PfPKG by inhibiting parasite phosphodiesterase activity induces premature PfSUB1 discharge and egress of developmentally immature, non-invasive parasites. Our findings identify the signalling pathway that regulates PfSUB1 function and egress, and raise the possibility of targeting PfPKG or parasite phosphodiesterases in therapeutic approaches to dysregulate critical protease-mediated steps in the parasite life cycle.

  1. In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors.

    Science.gov (United States)

    Torcellan, Tommaso; Hampton, Henry R; Bailey, Jacqueline; Tomura, Michio; Brink, Robert; Chtanova, Tatyana

    2017-05-30

    Immune therapy is rapidly gaining prominence in the clinic as a major weapon against cancer. Whereas much attention has been focused on the infiltration of tumors by immune cells, the subsequent fate of these infiltrates remains largely unexplored. We therefore established a photoconversion-based model that allowed us to label tumor-infiltrating immune cells and follow their migration. Using this system, we identified a population of tumor-experienced cells that emigrate from primary tumors to draining lymph nodes via afferent lymphatic vessels. Although the majority of tumor-infiltrating cells were myeloid, T cells made up the largest population of tumor-egressing leukocytes. Strikingly, the subset composition of tumor-egressing T cells was greatly skewed compared with those that had infiltrated the tumor and those resident in the draining lymph node. Some T-cell subsets such as CD8(+) T cells emigrated more readily; others including CD4(-)CD8(-) T cells were preferentially retained, suggesting that specific mechanisms guide immune cell egress from tumors. Furthermore, tumor-egressing T cells were more activated and displayed enhanced effector function in comparison with their lymph node counterparts. Finally, we demonstrated that tumor-infiltrating T cells migrate to distant secondary tumors and draining lymph nodes, highlighting a mechanism whereby tumor-experienced effector T cells may mediate antitumor immunity at metastatic sites. Thus, our results provide insights into migration and function of tumor-infiltrating immune cells and the role of these cells in tumor immunity outside of primary tumor deposits.

  2. 36 CFR 14.5 - Nature of interest granted; settlement on right-of-way; rights of ingress and egress.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Nature of interest granted; settlement on right-of-way; rights of ingress and egress. 14.5 Section 14.5 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR RIGHTS-OF-WAY Nature of Interest § 14.5 Nature...

  3. Windows with improved energy performance

    DEFF Research Database (Denmark)

    Noyé, Peter Anders; Laustsen, Jacob Birck; Svendsen, Svend

    2002-01-01

    the paper describes how the net energy gain from a complete typical window can be increased in a fairly simple way by reducing the frame width and using glass with low iron content. The changes primary increase the g-value. All improvements are based on existing technology and manufacturing methods...... performances. During the last 20 years the U-value of the glazing part of windows has been improved considerably, but the frame part has not followed the same development with respect to energy performance. Therefore an increasingly large part of the total heat loss through windows is relating to the frame...... part, for which reason, as far as energy efficiency and total economy are concerned, it has become more interesting to further develop frame structures. Traditionally, the energy performance of windows has primarily been characterised by the heat loss coefficient, U-value. However as the heat loss has...

  4. A window on urban sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Stigt, Rien van, E-mail: rien.vanstigt@hu.nl [Research Center for Technology and Innovation, Utrecht University of Applied Sciences, P.O. Box 182, 3500 AD Utrecht (Netherlands); Driessen, Peter P.J., E-mail: p.driessen@uu.nl [Copernicus Institute of Sustainable Development, Faculty of Geosciences, Utrecht University, P.O. Box 80.115, 3508 TC Utrecht (Netherlands); Spit, Tejo J.M., E-mail: T.J.M.Spit@uu.nl [Department of Human Geography and Spatial Planning, Faculty of Geosciences, Utrecht University, P.O. Box 80.115, 3508 TC Utrecht (Netherlands)

    2013-09-15

    Sustainable urban development requires the integration of environmental interests in urban planning. Although various methods of environmental assessment have been developed, plan outcomes are often disappointing due to the complex nature of decision-making in urban planning, which takes place in multiple arenas within multiple policy networks involving diverse stakeholders. We argue that the concept of ‘decision windows’ can structure this seemingly chaotic chain of interrelated decisions. First, explicitly considering the dynamics of the decision-making process, we further conceptualized decision windows as moments in an intricate web of substantively connected deliberative processes where issues are reframed within a decision-making arena, and interests may be linked within and across arenas. Adopting this perspective in two case studies, we then explored how decision windows arise, which factors determine their effectiveness and how their occurrence can be influenced so as to arrive at more sustainable solutions. We conclude that the integration of environmental interests in urban planning is highly dependent on the ability of the professionals involved to recognize and manipulate decision windows. Finally, we explore how decision windows may be opened. -- Highlights: • Decision-making about sustainable urban development occurs in networks. • The concept of ‘decision windows’ was further elaborated. • Decision windows help understand how environmental interests enter decision-making. • Decision windows can, to some extent, be influenced.

  5. Quinoxaline-based inhibitors of Ebola and Marburg VP40 egress.

    Science.gov (United States)

    Loughran, H Marie; Han, Ziying; Wrobel, Jay E; Decker, Sarah E; Ruthel, Gordon; Freedman, Bruce D; Harty, Ronald N; Reitz, Allen B

    2016-08-01

    We prepared a series of quinoxalin-2-mercapto-acetyl-urea analogs and evaluated them for their ability to inhibit viral egress in our Marburg and Ebola VP40 VLP budding assays in HEK293T cells. We also evaluated selected compounds in our bimolecular complementation assay (BiMC) to detect and visualize a Marburg mVP40-Nedd4 interaction in live mammalian cells. Antiviral activity was assessed for selected compounds using a live recombinant vesicular stomatitis virus (VSV) (M40 virus) that expresses the EBOV VP40 PPxY L-domain. Finally selected compounds were evaluated in several ADME assays to have an early assessment of their drug properties. Our compounds had low nM potency in these assays (e.g., compounds 21, 24, 26, 39), and had good human liver microsome stability, as well as little or no inhibition of P450 3A4.

  6. 拥抱Windows 10

    Institute of Scientific and Technical Information of China (English)

    王春海

    2015-01-01

    微软新一代操作系统Windows10已正式发布,新系统统一PC、平板、手机和Xbox等多个平台,在性能、安全性和用户体验方面都有全面提升,并对系统底层、开始菜单、操作中心等做出多项改进,包括更智慧的Cortana语音助理、全新多桌面体验和新的开始选单等。除此之外,Windows10还加强了安全性的设计,Windows10的内核版本直接从Windows8.1的6.4提升到了10.0,操作系统的底层架构和安全特性发生了多项重大变化。在初次使用Windows10的时候,可以看到“手机、平板”的风格到处都是。

  7. Switchable Materials for Smart Windows.

    Science.gov (United States)

    Wang, Yang; Runnerstrom, Evan L; Milliron, Delia J

    2016-06-07

    This article reviews the basic principles of and recent developments in electrochromic, photochromic, and thermochromic materials for applications in smart windows. Compared with current static windows, smart windows can dynamically modulate the transmittance of solar irradiation based on weather conditions and personal preferences, thus simultaneously improving building energy efficiency and indoor human comfort. Although some smart windows are commercially available, their widespread implementation has not yet been realized. Recent advances in nanostructured materials provide new opportunities for next-generation smart window technology owing to their unique structure-property relations. Nanomaterials can provide enhanced coloration efficiency, faster switching kinetics, and longer lifetime. In addition, their compatibility with solution processing enables low-cost and high-throughput fabrication. This review also discusses the importance of dual-band modulation of visible and near-infrared (NIR) light, as nearly 50% of solar energy lies in the NIR region. Some latest results show that solution-processable nanostructured systems can selectively modulate the NIR light without affecting the visible transmittance, thus reducing energy consumption by air conditioning, heating, and artificial lighting.

  8. Windows Server 2012 R2 administrator cookbook

    CERN Document Server

    Krause, Jordan

    2015-01-01

    This book is intended for system administrators and IT professionals with experience in Windows Server 2008 or Windows Server 2012 environments who are looking to acquire the skills and knowledge necessary to manage and maintain the core infrastructure required for a Windows Server 2012 and Windows Server 2012 R2 environment.

  9. Teach yourself visually Windows 8

    CERN Document Server

    McFedries, Paul

    2012-01-01

    A practical guide for visual learners eager to get started with Windows 8 If you learn more quickly when you can see how things are done, this Visual guide is the easiest way to get up and running on Windows 8. It covers more than 150 essential Windows tasks, using full-color screen shots and step-by-step instructions to show you just what to do. Learn your way around the interface and how to install programs, set up user accounts, play music and other media files, download photos from your digital camera, go online, set up and secure an e-mail account, and much more. The tried-and-true format

  10. Windows Server 2012 : Uudet ominaisuudet ja muutokset

    OpenAIRE

    2013-01-01

    Tämän opintyön tarkoituksena on valottaa Windows Server 2012 -käyttöjärjestelmän muutoksia verrattuna vanhaan Windows Server 2008 R2 -versioon. Työ aloitettiin ennen Windows Server 2012 -julkaisua Release Candidate -version testauksella ja myöhemmin julkaisun jälkeen Windows Serverin kokeiluversiolla. Työssä on silti ajankohtaista tietoa Windows Server 2012:sta. Aluksi käsitellään Windows Servereiden kehityskaarta lyhyesti ja käsitellään uusinta Windows Serveriä tuotteena se...

  11. Windows 7 is supported at CERN

    CERN Multimedia

    IT Department

    2010-01-01

    The new version of the Windows operating system - Windows 7 - is now officially supported at CERN. Windows 7 32-bit is now the default operating system for the new computers at CERN. What’s new in Windows 7 Users of Windows XP will find many new features and options. Users of Windows Vista will feel very familiar with one major difference: higher performance and better responsiveness of the operating system. Other enhancements include: refined Aero desktop that makes it easier to navigate between your different application windows; new snapping windows that allows user to resize a window simply by dragging it to the edge of the screen and “pin” that allows grouping and arranging often accessed applications on the taskbar. Windows 7 introduces the new concept of libraries – containers for user files that have links to different local or network folders. By default, users can see four libraries: Documents, Music, Pictures and Videos. These libraries point to the cor...

  12. Windows 7 Server名称之谜

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    按理说,Windows 7 Server 也算得上是一款新系统,为何不见其介绍呢?其实“Windows 7 Server”只是我们这些Windows拥戴者给它的命名,微软在研发Windows7的服务器版本时,并没有用“Windows 7 Server”作为开发代号,而是命名为“Windows Server 2008 R2”,这表示Windows7的服务器版本并不像是从Windows 2000 Server到Windows Server 2003式的重大产品升级,只是对现有Windows Server2008的一次更新,或者说是Windows Seryer 2008的增强版。

  13. Thermal bridges of modern windows

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan de Place; Møller, Eva B.; Nielsen, Anker

    2013-01-01

    With its focus on reduced energy consumption, contemporary housing construction requires a highly insulated and airtight building envelope with as few thermal bridges as possible.Windows must be carefully designed, as thermal bridges can lead to surface condensation or mold growth, even if the wi......With its focus on reduced energy consumption, contemporary housing construction requires a highly insulated and airtight building envelope with as few thermal bridges as possible.Windows must be carefully designed, as thermal bridges can lead to surface condensation or mold growth, even...

  14. Windows Vista Administrator's Pocket Guide

    CERN Document Server

    Stanek, William R

    2007-01-01

    Portable and precise, this pocket-sized guide delivers immediate answers for the day-to-day administration of Windows Vista. Zero in on core support and maintenance tasks using quick-reference tables, instructions, and lists. You'll get the precise information you need to solve problems and get the job done-whether you're at your desk or in the field! Get fast facts to: Install and configure Windows Vista-and optimize the user workspaceMaintain operating system components, hardware devices, and driversCreate user and group accounts-and control rights and permissionsAdminister group policy se

  15. *New* CRITICAL Windows Security patch

    CERN Multimedia

    2003-01-01

    On 10 September 2003, Microsoft issued a new CRITICAL security patch, MS03-039. It must be URGENTLY applied on ALL WINDOWS systems, which are not centrally managed for security patches. This includes Experiment computers, Home computers and Windows Portable and Desktop systems not running NICE. Details of the security hole and patch for MS03-039 (which also includes MS03-026) are at: http://cern.ch/it-div/news/hotfix-MS03-039.asp http://www.microsoft.com/technet/security/bulletin/MS03-039.asp

  16. *New*: CRITICAL Windows Security patch

    CERN Multimedia

    2003-01-01

    On 10 September 2003, Microsoft issued a new CRITICAL security patch, MS03-039. It must be URGENTLY applied on ALL WINDOWS systems, which are not centrally managed for security patches. This includes Experiment computers, Home computers and Windows Portable and Desktop systems not running NICE. Details of the security hole and patch for MS03-039 (which also includes MS03-026) are at: http://cern.ch/it-div/news/hotfix-MS03-039.asp http://www.microsoft.com/technet/security/bulletin/MS03-039.asp

  17. Microsoft Windows Server Administration Essentials

    CERN Document Server

    Carpenter, Tom

    2011-01-01

    The core concepts and technologies you need to administer a Windows Server OS Administering a Windows operating system (OS) can be a difficult topic to grasp, particularly if you are new to the field of IT. This full-color resource serves as an approachable introduction to understanding how to install a server, the various roles of a server, and how server performance and maintenance impacts a network. With a special focus placed on the new Microsoft Technology Associate (MTA) certificate, the straightforward, easy-to-understand tone is ideal for anyone new to computer administration looking t

  18. Windows with improved energy performance

    DEFF Research Database (Denmark)

    Noyé, Peter Anders; Laustsen, Jacob Birck; Svendsen, Svend

    2002-01-01

    the paper describes how the net energy gain from a complete typical window can be increased in a fairly simple way by reducing the frame width and using glass with low iron content. The changes primary increase the g-value. All improvements are based on existing technology and manufacturing methods...... part, for which reason, as far as energy efficiency and total economy are concerned, it has become more interesting to further develop frame structures. Traditionally, the energy performance of windows has primarily been characterised by the heat loss coefficient, U-value. However as the heat loss has...

  19. Exceptional and Spinorial Conformal Windows

    DEFF Research Database (Denmark)

    Mojaza, Matin; Pica, Claudio; Ryttov, Thomas

    2012-01-01

    We study the conformal window of gauge theories containing fermionic matter fields, where the gauge group is any of the exceptional groups with the fermions transforming according to the fundamental and adjoint representations and the orthogonal groups where the fermions transform according...

  20. Structural Features of Apicomplexan Pore-Forming Proteins and Their Roles in Parasite Cell Traversal and Egress.

    Science.gov (United States)

    Guerra, Alfredo J; Carruthers, Vern B

    2017-08-29

    Apicomplexan parasites cause diseases, including malaria and toxoplasmosis, in a range of hosts, including humans. These intracellular parasites utilize pore-forming proteins that disrupt host cell membranes to either traverse host cells while migrating through tissues or egress from the parasite-containing vacuole after replication. This review highlights recent insight gained from the newly available three-dimensional structures of several known or putative apicomplexan pore-forming proteins that contribute to cell traversal or egress. These new structural advances suggest that parasite pore-forming proteins use distinct mechanisms to disrupt host cell membranes at multiple steps in parasite life cycles. How proteolytic processing, secretion, environment, and the accessibility of lipid receptors regulate the membranolytic activities of such proteins is also discussed.

  1. Proteolytic Activation of the Essential Parasitophorous Vacuole Cysteine Protease SERA6 Accompanies Malaria Parasite Egress from Its Host Erythrocyte*

    Science.gov (United States)

    Ruecker, Andrea; Shea, Michael; Hackett, Fiona; Suarez, Catherine; Hirst, Elizabeth M. A.; Milutinovic, Katarina; Withers-Martinez, Chrislaine; Blackman, Michael J.

    2012-01-01

    The malaria parasite replicates within an intraerythrocytic parasitophorous vacuole (PV). The PV and host cell membranes eventually rupture, releasing merozoites in a process called egress. Certain inhibitors of serine and cysteine proteases block egress, indicating a crucial role for proteases. The Plasmodium falciparum genome encodes nine serine-repeat antigens (SERAs), each of which contains a central domain homologous to the papain-like (clan CA, family C1) protease family. SERA5 and SERA6 are indispensable in blood-stage parasites, but the function of neither is known. Here we show that SERA6 localizes to the PV where it is precisely cleaved just prior to egress by an essential serine protease called PfSUB1. Mutations that replace the predicted catalytic Cys of SERA6, or that block SERA6 processing by PfSUB1, could not be stably introduced into the parasite genomic sera6 locus, indicating that SERA6 is an essential enzyme and that processing is important for its function. We demonstrate that cleavage of SERA6 by PfSUB1 converts it to an active cysteine protease. Our observations reveal a proteolytic activation step in the malarial PV that may be required for release of the parasite from its host erythrocyte. PMID:22984267

  2. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    2008-01-01

    windows have already been developed and prototypes constructed for laboratory test and a third generation of the window design is now in the developing and designing face in a new project. The first window constructed was made of wood profiles and a low-energy double glazing unit. The second and third......This paper presents some of the research done during the last 8 years at the Technical University of Denmark developing improved low-energy window solutions. The focus has been on maximizing the net energy gain of windows for residential buildings. The net energy gain of windows is the solar gain...

  3. Forensic Analysis of Windows Registry Against Intrusion

    Directory of Open Access Journals (Sweden)

    Haoyang Xie

    2012-03-01

    Full Text Available Windows Registry forensics is an important branch of computer and network forensics. Windows Registry is often considered as the heart of Windows Operating Systems because it contains allof the configuration setting of specific users, groups, hardware, software, and networks. Therefore, Windows Registry can be viewed as a gold mine of forensic evidences which could be used in courts. This paper introduces the basics of Windows Registry, describes its structure and its keys and subkeys thathave forensic values. This paper also discusses how the Windows Registry forensic keys can be applied in intrusion detection.

  4. Windows 8 and Office 2013 for dummies

    CERN Document Server

    Rathbone, Andy

    2013-01-01

    Learn to: Navigate the Windows 8 Start screenCreate user accounts and set passwordsUse Word, Excel®, PowerPoint®, and Outlook® Master the basics of Windows 8 and Office 2013! Windows and Office work together to turn your PC into a productivity tool. The unique Windows 8 interface combines with updates to Office 2013 to create a new computing experience. This book offers quick answers for when you get stuck. Learn your way around the Windows 8 Start screen and Charms bar as well as Office 2013 applications.The new Windows - see how to laun

  5. Predicting Electrochromic Smart Window Performance

    Energy Technology Data Exchange (ETDEWEB)

    Degerman Engfeldt, Johnny

    2012-07-01

    The building sector is one of the largest consumers of energy, where the cooling of buildings accounts for a large portion of the total energy consumption. Electrochromic (EC) smart windows have a great potential for increasing indoor comfort and saving large amounts of energy for buildings. An EC device can be viewed as a thin-film electrical battery whose charging state is manifested in optical absorption, i.e. the optical absorption increases with increased state-of-charge (SOC) and decreases with decreased state-of-charge. It is the EC technology's unique ability to control the absorption (transmittance) of solar energy and visible light in windows with small energy effort that can reduce buildings' cooling needs. Today, the EC technology is used to produce small windows and car rearview mirrors, and to reach the construction market it is crucial to be able to produce large area EC devices with satisfactory performance. A challenge with up-scaling is to design the EC device system with a rapid and uniform coloration (charging) and bleaching (discharging). In addition, up-scaling the EC technology is a large economic risk due to its expensive production equipment, thus making the choice of EC material and system extremely critical. Although this is a well-known issue, little work has been done to address and solve these problems. This thesis introduces a cost-efficient methodology, validated with experimental data, capable of predicting and optimizing EC device systems' performance in large area applications, such as EC smart windows. This methodology consists of an experimental set-up, experimental procedures and a two dimensional current distribution model. The experimental set-up, based on camera vision, is used in performing experimental procedures to develop and validate the model and methodology. The two-dimensional current distribution model takes secondary current distribution with charge transfer resistance, ohmic and time

  6. Facilities & Leadership

    Data.gov (United States)

    Department of Veterans Affairs — The facilities web service provides VA facility information. The VA facilities locator is a feature that is available across the enterprise, on any webpage, for the...

  7. Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

    Science.gov (United States)

    Fox, Julie M; Long, Feng; Edeling, Melissa A; Lin, Hueylie; van Duijl-Richter, Mareike K S; Fong, Rachel H; Kahle, Kristen M; Smit, Jolanda M; Jin, Jing; Simmons, Graham; Doranz, Benjamin J; Crowe, James E; Fremont, Daved H; Rossmann, Michael G; Diamond, Michael S

    2015-11-19

    We screened a panel of mouse and human monoclonal antibodies (MAbs) against chikungunya virus and identified several with inhibitory activity against multiple alphaviruses. Passive transfer of broadly neutralizing MAbs protected mice against infection by chikungunya, Mayaro, and O'nyong'nyong alphaviruses. Using alanine-scanning mutagenesis, loss-of-function recombinant proteins and viruses, and multiple functional assays, we determined that broadly neutralizing MAbs block multiple steps in the viral lifecycle, including entry and egress, and bind to a conserved epitope on the B domain of the E2 glycoprotein. A 16 Å resolution cryo-electron microscopy structure of a Fab fragment bound to CHIKV E2 B domain provided an explanation for its neutralizing activity. Binding to the B domain was associated with repositioning of the A domain of E2 that enabled cross-linking of neighboring spikes. Our results suggest that B domain antigenic determinants could be targeted for vaccine or antibody therapeutic development against multiple alphaviruses of global concern.

  8. Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

    Directory of Open Access Journals (Sweden)

    Tzviya Zeev-Ben-Mordehai

    2015-12-01

    Full Text Available Although nucleo-cytoplasmic transport is typically mediated through nuclear pore complexes, herpesvirus capsids exit the nucleus via a unique vesicular pathway. Together, the conserved herpesvirus proteins pUL31 and pUL34 form the heterodimeric nuclear egress complex (NEC, which, in turn, mediates the formation of tight-fitting membrane vesicles around capsids at the inner nuclear membrane. Here, we present the crystal structure of the pseudorabies virus NEC. The structure revealed that a zinc finger motif in pUL31 and an extensive interaction network between the two proteins stabilize the complex. Comprehensive mutational analyses, characterized both in situ and in vitro, indicated that the interaction network is not redundant but rather complementary. Fitting of the NEC crystal structure into the recently determined cryoEM-derived hexagonal lattice, formed in situ by pUL31 and pUL34, provided details on the molecular basis of NEC coat formation and inner nuclear membrane remodeling.

  9. A molecular pathway for the egress of ammonia produced by nitrogenase

    Science.gov (United States)

    Dance, Ian

    2013-11-01

    Nitrogenase converts N2 to NH3, at one face of an Fe-Mo-S cluster (FeMo-co) buried in the protein. Through exploration of cavities in the structures of nitrogenase proteins, a pathway for the egress of ammonia from its generation site to the external medium is proposed. This pathway is conserved in the three species Azotobacter vinelandii, Klebsiella pneumoniae and Clostridium pasteurianum. A molecular mechanism for the translocation of NH3 by skipping through a sequence of hydrogen bonds involving eleven water molecules and surrounding aminoacids has been developed. The putative mechanism requires movement aside of some water molecules by up to ~ 1Å. Consistent with this, the surrounding protein is comprised of different chains and has little secondary structure: protein fluctuations are part of the mechanism. This NH3 pathway is well separated from the water chain and embedded proton wire that have been proposed for serial supply of protons to FeMo-co. Verification procedures are suggested.

  10. RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

    Science.gov (United States)

    Chopin, Michaël; Preston, Simon P; Lun, Aaron T L; Tellier, Julie; Smyth, Gordon K; Pellegrini, Marc; Belz, Gabrielle T; Corcoran, Lynn M; Visvader, Jane E; Wu, Li; Nutt, Stephen L

    2016-04-13

    Plasmacytoid dendritic cells (pDCs) represent a unique immune cell type that responds to viral nucleic acids through the rapid production of type I interferons. Within the hematopoietic system, the transcription factor RUNX2 is exclusively expressed in pDCs and is required for their peripheral homeostasis. Here, we show that RUNX2 plays an essential role in promoting pDC localization and function. RUNX2 is required for the appropriate expression of the integrin-mediated adhesion machinery, as well as for the down-modulation of the chemokine receptor CXCR4, which allows pDC egress into the circulation. RUNX2 also facilitates the robust response to viral infection through the control of IRF7, the major regulator of type I interferon production. Mice lacking one copy of Runx2 have reduced numbers of peripheral pDCs and IFN-α expression, which might contribute to the reported difficulties of individuals with cleidocranial dysplasia, who are haploinsufficient for RUNX2, to clear viral infections.

  11. RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

    Directory of Open Access Journals (Sweden)

    Michaël Chopin

    2016-04-01

    Full Text Available Plasmacytoid dendritic cells (pDCs represent a unique immune cell type that responds to viral nucleic acids through the rapid production of type I interferons. Within the hematopoietic system, the transcription factor RUNX2 is exclusively expressed in pDCs and is required for their peripheral homeostasis. Here, we show that RUNX2 plays an essential role in promoting pDC localization and function. RUNX2 is required for the appropriate expression of the integrin-mediated adhesion machinery, as well as for the down-modulation of the chemokine receptor CXCR4, which allows pDC egress into the circulation. RUNX2 also facilitates the robust response to viral infection through the control of IRF7, the major regulator of type I interferon production. Mice lacking one copy of Runx2 have reduced numbers of peripheral pDCs and IFN-α expression, which might contribute to the reported difficulties of individuals with cleidocranial dysplasia, who are haploinsufficient for RUNX2, to clear viral infections.

  12. A pore-forming toxin enables Serratia a nonlytic egress from host cells.

    Science.gov (United States)

    Di Venanzio, Gisela; Lazzaro, Martina; Morales, Enrique S; Krapf, Darío; García Véscovi, Eleonora

    2017-02-01

    Several pathogens co-opt host intracellular compartments to survive and replicate, and they thereafter disperse progeny to prosper in a new niche. Little is known about strategies displayed by Serratia marcescens to defeat immune responses and disseminate afterwards. Upon invasion of nonphagocytic cells, Serratia multiplies within autophagosome-like vacuoles. These Serratia-containing vacuoles (SeCV) circumvent progression into acidic/degradative compartments, avoiding elimination. In this work, we show that ShlA pore-forming toxin (PFT) commands Serratia escape from invaded cells. While ShlA-dependent, Ca(2)(+) local increase was shown in SeCVs tight proximity, intracellular Ca(2)(+) sequestration prevented Serratia exit. Accordingly, a Ca(2)(+) surge rescued a ShlA-deficient strain exit capacity, demonstrating that Ca(2)(+) mobilization is essential for egress. As opposed to wild-type-SeCV, the mutant strain-vacuole was wrapped by actin filaments, showing that ShlA expression rearranges host actin. Moreover, alteration of actin polymerization hindered wild-type Serratia escape, while increased intracellular Ca(2)(+) reorganized the mutant strain-SeCV actin distribution, restoring wild-type-SeCV phenotype. Our results demonstrate that, by ShlA expression, Serratia triggers a Ca(2)(+) signal that reshapes cytoskeleton dynamics and ends up pushing the SeCV load out of the cell, in an exocytic-like process. These results disclose that PFTs can be engaged in allowing bacteria to exit without compromising host cell integrity.

  13. Integrated windows-based control system for an electron microscope

    Science.gov (United States)

    Ruan, Shengyang; Kapp, Oscar H.

    1994-12-01

    A Windows application has been developed for management and operation of beam instruments such as electron or ion microscopes. It provides a facility that allows an operator to manage a complicated instrument with minimal effort, primarily under mouse control. The hardware control components used on similar instruments (e.g., the scanning transmission electron microscopes in our lab), such as toggles, buttons, and potentiometers for adjustments on various scales, are all replaced by the controls of the Windows application and are addressable on a single screen. The new controls in this program (via adjustable software settings) offer speed of response and smooth operation providing tailored control of various instrument parameters. Along with the controls offering single parameter adjustment, a two-dimensional control was developed that allows two parameters to be coupled and addressed simultaneously. This capability provides convenience for such tasks as ``finding the beam'' and directing it to a location of interest on the specimen. Using an icon-based display, this Windows application provides better integrated and more robust information for monitoring instrument status than the indicators and meters of the traditional instrument controls. As a Windows application, this program is naturally able to share the resources of the Windows system and is thus able to link to many other applications such as our image acquisition and processing programs. Computer control provides automatic protection and instant diagnostics for the experimental instrument. This Windows application is fully functional and is in daily use to control a new type of electron microscope developed in our lab.

  14. Integrated windows-based control system for an electron microscope

    Energy Technology Data Exchange (ETDEWEB)

    Ruan, S. (The Enrico Fermi Institute, The University of Chicago, Chicago, Illinois 60637 (United States)); Kapp, O.H. (The Department of Radiology and The Enrico Fermi Institute, The University of Chicago, Chicago, Illinois 60637 (United States))

    1994-12-01

    A Windows application has been developed for management and operation of beam instruments such as electron or ion microscopes. It provides a facility that allows an operator to manage a complicated instrument with minimal effort, primarily under mouse control. The hardware control components used on similar instruments (e.g., the scanning transmission electron microscopes in our lab), such as toggles, buttons, and potentiometers for adjustments on various scales, are all replaced by the controls of the Windows application and are addressable on a single screen. The new controls in this program (via adjustable software settings) offer speed of response and smooth operation providing tailored control of various instrument parameters. Along with the controls offering single parameter adjustment, a two-dimensional control was developed that allows two parameters to be coupled and addressed simultaneously. This capability provides convenience for such tasks as finding the beam'' and directing it to a location of interest on the specimen. Using an icon-based display, this Windows application provides better integrated and more robust information for monitoring instrument status than the indicators and meters of the traditional instrument controls. As a Windows application, this program is naturally able to share the resources of the Windows system and is thus able to link to many other applications such as our image acquisition and processing programs. Computer control provides automatic protection and instant diagnostics for the experimental instrument. This Windows application is fully functional and is in daily use to control a new type of electron microscope developed in our lab.

  15. *NEW* CRITICAL Windows Security patches

    CERN Multimedia

    2003-01-01

    On 3 October and 10 September 2003, Microsoft issued new CRITICAL security patches MS03-040 and MS03-039. They must be URGENTLY applied on ALL WINDOWS systems, which are not centrally managed for security patches. This includes Experiment computers, Home computers and Windows Portable and Desktop systems not running NICE. Details of the security holes and patches are at: MS03-039: http://cern.ch/it-div/news/hotfix-MS03-039.asp http://www.microsoft.com/technet/security/bulletin/MS03-039.asp MS03-040: http://cern.ch/it-div/news/hotfix-MS03-040.asp http://www.microsoft.com/technet/security/bulletin/MS03-040.asp

  16. Electrochromic windows - Applications for aircraft

    Science.gov (United States)

    Harris, Caroline S.; Greenberg, Charles B.

    1989-04-01

    A transparent, solid-state, electrochromic device is described. It demonstrates deep switching in the near infrared and visible spectral regions and good room temperature cycling stability. The response appears reasonably uniform over a 14 cm x 28 cm area, which gives hope for achieving large parts for cockpit and cabin windows. The reversible darkening of the transparency, controlled by an applied voltage or current, has potential application in aircraft to reduce glare and solar heat load to pilots and passengers. The active material in the device is a thin tungsten oxide film which is incorporated into a complex, multilayered structure, essentially that of a transparent battery. The performance of the window is discussed in terms of its configuration, its similarities with commercial batteries and issues critical to aircraft.

  17. Biochemistry Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Biochemistry Facility provides expert services and consultation in biochemical enzyme assays and protein purification. The facility currently features 1) Liquid...

  18. A Window of Chinese Folklore

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    PRESENI-DAY Chinese folk-lore is a window throughwhich one can see Chineseculture;one can see contemporarylife,but mostly one views traditional folk culture.China’s 5,000 years ofhistory,civilization,vast lands and national background have brought afascinating variety of local customsto China’s 56 nationalities.The fol-lowing is a brief introduction to their religious beliefs,sacrificial ritesand festive gatherings.

  19. Windows Memory Forensic Data Visualization

    Science.gov (United States)

    2014-06-12

    captures from Windows machines and the methodology for extracting digital artifacts from forensic memory captures. The two types of malware implemented on...proposed to improve upon the design implemented in the D3 JavaScript Visualization Tool. 7 II. Literature Review Due to the recent rise...18. Resource Slice Selected – Associated Process Nodes Highlighted. ... vice\\Nam~~~~~~~~ffi~~ iFr ~)~~~ ... vice\\NamedPipe\

  20. Exceptional and Spinorial Conformal Windows

    CERN Document Server

    Mojaza, Matin; Ryttov, Thomas A; Sannino, Francesco

    2012-01-01

    We study the conformal window of gauge theories containing fermionic matter fields, where the gauge group is any of the exceptional groups with the fermions transforming according to the fundamental and adjoint representations and the orthogonal groups where the fermions transform according to a spinorial representation. We investigate the phase diagram using a purely perturbative four loop analysis, the all-orders beta function and the ladder approximation.

  1. Electrochromic Windows: Advanced Processing Technology

    Energy Technology Data Exchange (ETDEWEB)

    SAGE Electrochromics, Inc

    2006-12-13

    This project addresses the development of advanced fabrication capabilities for energy saving electrochromic (EC) windows. SAGE EC windows consist of an inorganic stack of thin films deposited onto a glass substrate. The window tint can be reversibly changed by the application of a low power dc voltage. This property can be used to modulate the amount of light and heat entering buildings (or vehicles) through the glazings. By judicious management of this so-called solar heat gain, it is possible to derive significant energy savings due to reductions in heating lighting, and air conditioning (HVAC). Several areas of SAGE’s production were targeted during this project to allow significant improvements to processing throughput, yield and overall quality of the processing, in an effort to reduce the cost and thereby improve the market penetration. First, the overall thin film process was optimized to allow a more robust set of operating points to be used, thereby maximizing the yield due to the thin film deposition themselves. Other significant efforts aimed at improving yield were relating to implementing new procedures and processes for the manufacturing process, to improve the quality of the substrate preparation, and the quality of the IGU fabrication. Furthermore, methods for reworking defective devices were developed, to enable devices which would otherwise be scrapped to be made into useful product. This involved the in-house development of some customized equipment. Finally, the improvements made during this project were validated to ensure that they did not impact the exceptional durability of the SageGlass® products. Given conservative estimates for cost and market penetration, energy savings due to EC windows in residences in the US are calculated to be of the order 0.026 quad (0.026×1015BTU/yr) by the year 2017.

  2. Conformal window and Landau singularities

    CERN Document Server

    Grunberg, G

    2001-01-01

    A physical characterization of Landau singularities is emphasized, which should trace the lower boundary N_f^* of the conformal window in QCD and supersymmetric QCD. A natural way to disentangle ``perturbative'' from ``non-perturbative'' contributions below N_f^* is suggested. Assuming an infrared fixed point is present in the perturbative part of the QCD coupling even in some range below N_f^* leads to the condition gamma(N_f^*)=1, where gamma is the critical exponent. Using the Banks-Zaks expansion, one gets 4window. Some evidence for such a fixed point in QCD is provided through a modified Banks-Zaks expansion. Conformal window amplitudes, which contain power contributions, are show...

  3. Energy Gaining Windows for Residental Buildings

    DEFF Research Database (Denmark)

    Kragh, Jesper; Laustsen, Jacob Birck; Svendsen, Svend

    This paper presents some of the research done during the last 8 years at the Technical University of Denmark developing improved low-energy window solutions. The focus has been on maximizing the net energy gain of windows for residential buildings. The net energy gain of windows is the solar gain...... windows have already been developed and prototypes constructed for laboratory test and a third generation of the window design is now in the developing and designing face in a new project. The first window constructed was made of wood profiles and a low-energy double glazing unit. The second and third...... and longer durability of the window. The glazing in these fiber reinforced polyester windows is both unsealed and sealed triple glazing units. To increase the net energy gain slim frame profiles have been developed to increase the glazing area and thereby the solar gain. The challenge when developing slim...

  4. Microsoft Windows Intune 20 Quickstart Administration

    CERN Document Server

    Overton, David

    2012-01-01

    This book is a concise and practical tutorial that shows you how to plan, set up and maintain Windows Intune and manage a group of PCs. If you are an administrator or partner who wants to plan, set up and maintain Windows Intune and manage a group of PCs then this book is for you . You should have a basic understanding of Windows administration, however, knowledge of Windows Intune would not be required.

  5. Windows Embedded创新不断

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    本刊讯 2月19日,微软Windows Embedded技术交流活动在微软办公室举行。微软的MVP(最有价值专家)详细介绍微软Windows Embedded的技术、开发和应用,包括:Windows EmbeddedCE、Windows XP Embedded、WEPOS等。

  6. Windows shell扩展技术

    Institute of Scientific and Technical Information of China (English)

    唐东明

    2005-01-01

    Windows shell提供了很多扩展编程接口,可使程序编制人员丰富Windows shell的功能.文中详细阐述了Windows shell的扩展技术,并讲解了如何用ATL开发Win-dows shell扩展组件的技术和方法.

  7. Windowing Waveform Relaxation of Initial Value Problems

    Institute of Scientific and Technical Information of China (English)

    Yao-lin Jiang

    2006-01-01

    We present a windowing technique of waveform relaxation for dynamic systems. An effective estimation on window length is derived by an iterative error expression provided here. Relaxation processes can be speeded up if one takes the windowing technique in advance. Numerical experiments are given to further illustrate the theoretical analysis.

  8. Spatial scan statistics using elliptic windows

    DEFF Research Database (Denmark)

    Christiansen, Lasse Engbo; Andersen, Jens Strodl; Wegener, Henrik Caspar

    of confocal elliptic windows and propose a new way to present the information when a spatial point process is considered. This method gives smooth changes for smooth expansions of the set of clusters. A simulation study is used to show how the elliptic windows outperforms the usual circular windows...

  9. Spatial scan statistics using elliptic windows

    DEFF Research Database (Denmark)

    Christiansen, Lasse Engbo; Andersen, Jens Strodl; Wegener, Henrik Caspar

    2006-01-01

    windows and propose a new way to present the information when a spatial point process is considered. This method gives smooth changes for smooth expansions of the set of clusters. A simulation study is used to show how the elliptic windows outperforms the usual circular windows. The proposed method...

  10. Purged window apparatus utilizing heated purge gas

    Science.gov (United States)

    Ballard, Evan O.

    1984-01-01

    A purged window apparatus utilizing tangentially injected heated purge gases in the vicinity of electromagnetic radiation transmitting windows, and a tapered external mounting tube to accelerate these gases to provide a vortex flow on the window surface and a turbulent flow throughout the mounting tube. Use of this apparatus prevents backstreaming of gases under investigation which are flowing past the mouth of the mounting tube which would otherwise deposit on the windows. Lengthy spectroscopic investigations and analyses can thereby be performed without the necessity of interrupting the procedures in order to clean or replace contaminated windows.

  11. Windows Command Line Administration Instant Reference

    CERN Document Server

    Mueller, John Paul

    2010-01-01

    The perfect companion to any book on Windows Server 2008 or Windows 7, and the quickest way to access critical information. Focusing just on the essentials of command-line interface (CLI), Windows Command-Line Administration Instant Reference easily shows how to quickly perform day-to-day tasks of Windows administration without ever touching the graphical user interface (GUI). Specifically designed for busy administrators, Windows Command-Line Administration Instant Reference replaces many tedious GUI steps with just one command at the command-line, while concise, easy to access answers provid

  12. Counterion-induced reversibly switchable transparency in smart windows.

    Science.gov (United States)

    Lee, Chang Hwan; Lim, Ho Sun; Kim, Jooyong; Cho, Jeong Ho

    2011-09-27

    Smart windows that can reversibly alternate between extreme optical characteristics via clicking counteranions of different hydration energies were developed on glass substrates through the facile spray-casting of poly[2-(methacryloyloxy)ethyltrimethylammonium chloride-co-3-(trimethoxysilyl)propyl methacrylate]. The optical transmittance was either 90.9% or 0% over the whole spectral range when alternately immersed in solutions containing thiocyanate (SCN(-)) or bis(trifluoromethane)sulfonimide (TFSI(-)) ions, respectively. The extreme optical transitions were attributed to formation of microporous structures via the molecular aggregation of polyelectrolyte chains bearing TFSI(-) ions in methanol. Because the smart windows were either highly transparent toward or completely blocking of incident light upon direct counterion exchange, this kind of nanotechnology may provide a new platform for efficiently conserving on energy usage in the interior of buildings.

  13. Explosive Fracturing of an F-16 Canopy for Through-Canopy Crew Egress

    Science.gov (United States)

    Bement, Laurence J.

    2000-01-01

    Through-canopy crew egress, such as in the Harrier (AV-8B) aircraft, expands escape envelopes by reducing seat ejection delays in waiting for canopy jettison. Adverse aircraft attitude and reduced forward flight speed can further increase the times for canopy jettison. However, the advent of heavy, high-strength polycarbonate canopies for bird-strike resistance has not only increased jettison times, but has made seat penetration impossible. The goal of the effort described in this paper was to demonstrate a method of explosively fracturing the F-16 polycarbonate canopy to allow through-canopy crew ejection. The objectives of this effort were to: 1. Mount the explosive materials on the exterior of the canopy within the mold line, 2. Minimize visual obstructions, 3. Minimize internal debris on explosive activation, 4. Operate within less than 10 ms, 5. Maintain the shape of the canopy after functioning to prevent major pieces from entering the cockpit, and 6. Minimize the resistance of the canopy to seat penetration. All goals and objectives were met in a full-scale test demonstration. In addition to expanding crew escape envelopes, this canopy fracture approach offers the potential for reducing system complexity, weight and cost, while increasing overall reliability, compared to current canopy jettison approaches. To comply with International Traffic in Arms Regulations (ITAR) and permit public disclosure, this document addresses only the principles of explosive fracturing of the F-16 canopy materials and the end result. ITAR regulations restrict information on improving the performance of weapon systems. Therefore, details on the explosive loads and final assembly of this canopy fracture approach, necessary to assure functional performance, are not included.

  14. Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

    Science.gov (United States)

    Liang, Jingjing; Sagum, Cari A.; Bedford, Mark T.; Sudol, Marius; Han, Ziying

    2017-01-01

    Ebola (EBOV) and Marburg (MARV) viruses are members of the Filoviridae family which cause outbreaks of hemorrhagic fever. The filovirus VP40 matrix protein is essential for virus assembly and budding, and its PPxY L-domain motif interacts with WW-domains of specific host proteins, such as Nedd4 and ITCH, to facilitate the late stage of virus-cell separation. To identify additional WW-domain-bearing host proteins that interact with VP40, we used an EBOV PPxY-containing peptide to screen an array of 115 mammalian WW-domain-bearing proteins. Using this unbiased approach, we identified BCL2 Associated Athanogene 3 (BAG3), a member of the BAG family of molecular chaperone proteins, as a specific VP40 PPxY interactor. Here, we demonstrate that the WW-domain of BAG3 interacts with the PPxY motif of both EBOV and MARV VP40 and, unexpectedly, inhibits budding of both eVP40 and mVP40 virus-like particles (VLPs), as well as infectious VSV-EBOV recombinants. BAG3 is a stress induced protein that regulates cellular protein homeostasis and cell survival through chaperone-mediated autophagy (CMA). Interestingly, our results show that BAG3 alters the intracellular localization of VP40 by sequestering VP40 away from the plasma membrane. As BAG3 is the first WW-domain interactor identified that negatively regulates budding of VP40 VLPs and infectious virus, we propose that the chaperone-mediated autophagy function of BAG3 represents a specific host defense strategy to counteract the function of VP40 in promoting efficient egress and spread of virus particles. PMID:28076420

  15. Professional Windows Embedded Compact 7

    CERN Document Server

    Phung, Samuel; Joubert, Thierry; Hall, Mike

    2011-01-01

    Learn to program an array of customized devices and solutions As a compact, highly efficient, scalable operating system, Windows Embedded Compact 7 (WEC7) is one of the best options for developing a new generation of network-enabled, media-rich, and service-oriented devices. This in-depth resource takes you through the benefits and capabilities of WEC7 so that you can start using this performance development platform today. Divided into several major sections, the book begins with an introduction and then moves on to coverage of OS design, application development, advanced application developm

  16. Windows Vista已亮相

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Windows Vista企业版已于11月底发布,而个人版将于明年1月30日推出。权威调研机构IDC本周三预计,Vista明年的销量可达到9000万套。在明年新售PC机中,90%的个人PC将安装Vista操作系统,而企业PC安装Vista的比例将只有35%。

  17. Use of UV-protective windows and window films to aid in the prevention of skin cancer.

    Science.gov (United States)

    Edlich, Richard F; Winters, Kathryne L; Cox, Mary Jude; Becker, Daniel G; Horowitz, Jed H; Nichter, Larry S; Britt, L D; Long, William B; Edlic, Elizabeth C

    2004-01-01

    automotive films in an effort to increase consumer awareness and demand for all professionally installed film window products. The Skin Cancer Foundation has also played a leadership role in certifying window films that limit UV transmission. The Panorama Designer and Safety Films are currently recommended for UV photoprotection by The Skin Cancer Foundation. On the basis of these innovative scientific and industrial advances in window and film photoprotective products, we recommend that they be used in all residential, commercial, and school facilities to provide photoprotection in an effort to reduce skin cancer.

  18. EFEKTIFITAS VARIASI NILAI WINDOW LEVEL TERHADAP KUALITAS HASIL CT SCAN THORAX LUNG WINDOW

    OpenAIRE

    dani, Rahma

    2014-01-01

    EFEKTIFITAS VARIASI NILAI WINDOW LEVEL TERHADAP KUALITAS HASIL CT SCAN THORAX LUNG WINDOW Rahmadani Jurusan Fisika, FMIPA, Universitas Hasanuddin, Makassar 90245, Indonesia Pembimbing Utama : Prof. Dr. H. Halmar Halide, M.Sc Pembimbing Pertama : Dahlang Tahir, M.Sc. Phd ABSTRAK Telah dilakukan penelitian untuk mengetahui efek variasi nilai window level terhadap kualitas hasil CT Scann thorax lung window dengan pengaturan window width 1000,1500, 2000 dengan varias...

  19. Windows 2012 Server network security securing your Windows network systems and infrastructure

    CERN Document Server

    Rountree, Derrick

    2013-01-01

    Windows 2012 Server Network Security provides the most in-depth guide to deploying and maintaining a secure Windows network. The book drills down into all the new features of Windows 2012 and provides practical, hands-on methods for securing your Windows systems networks, including: Secure remote access Network vulnerabilities and mitigations DHCP installations configuration MAC filtering DNS server security WINS installation configuration Securing wired and wireless connections Windows personal firewall

  20. Role of Sphingosine 1-Phosphate Receptor Type 1 in Lymphocyte Egress from Secondary Lymphoid Tissues and Thymus

    Institute of Scientific and Technical Information of China (English)

    Kenji Chiba; Hirofumi Matsuyuki; Yasuhiro Maeda; Kunio Sugahara

    2006-01-01

    Circulation of mature lymphocytes between blood and secondary lymphoid tissues plays a central role in the immune system. Homing of lymphocytes from blood into secondary lymphoid tissues beyond high endothelial venules is highly dependent on the interaction between the chemokines CCL19, CCL21, CXCL12, and CXCL13,and their receptors CCR7, CXCR4 and CXCR5. However, the molecular mechanism(s) of lymphocyte egress from secondary lymphoid tissues to lymph remained unclear. We have found a new class of immunomodulator, FTY720 by chemical modification of vegetative wasp-derived natural product, ISP-I (myriocin). FTY720 has been shown to be highly effective in experimental allograft and autoimmune disease models. A striking feature of FTY720 is the induction of a marked decrease in peripheral blood lymphocytes at doses that show immunomodulating activity in these models. The reduction of circulating lymphocytes by FTY720 is caused by sequestration of iymphocytes into secondary lymphoid tissues and thymus. FTY720 is rapidly converted to (S)-enantiomer of FTY720-phosphate[(S)-FTY720-P] by sphingosine kinase 2 in vivo. (S)-FTY720-P acting as a potent agonist of S1P receptor type 1(S1P1), induces long-term down-regulation of S1P1 on lymphocytes, and thereby inhibits the migration of lymphocytes toward S1P. Thus, it is presumed that FTY720-induced lymphocyte sequestration is due to the inhibition of S1P/S1P1-dependent lymphocyte egress from secondary lymphoid tissues and thymus by its active metabolite (S)-FTY720-P. Throughout the analysis of the mechanism of action of FTY720, it is clarified that S1P/S1P1 interaction plays an important role for lymphocyte egress from secondary lymphoid tissues and thymus.

  1. Broken Windows and Collective Efficacy

    Directory of Open Access Journals (Sweden)

    Aldrin Abdullah

    2015-01-01

    Full Text Available The broken windows thesis posits that signs of disorder increase crime and fear, both directly and indirectly. Although considerable theoretical evidence exists to support the idea that disorder is positively related to fear of crime, the empirical literature on examining the indirect effect of the individual’s perception of incivilities on fear of crime is limited, especially in developing countries. This research was conducted to assess the indirect relationship between perceived disorder and fear of crime through collective efficacy. A total of 235 households from Penang, Malaysia, participated in this study. Results reveal that high perception of disorder is negatively associated with collective efficacy. High collective efficacy is associated with low fear of crime. Moreover, a significant and indirect effect of disorder on fear of crime exists through collective efficacy. The results provide empirical support for the broken windows theory in the Malaysian context and suggest that both environmental conditions and interactions of residents play a role in the perceived fear of crime.

  2. An Experimental and Analytical Evaluation of Wall And Window Retrofit Configurations: Supporting the Residential Retrofit Best Practices Guide

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, Therese K [ORNL; Petrie, Thomas [ORNL; Kosny, Jan [ORNL; Childs, Phillip W [ORNL; Atchley, Jerald Allen [ORNL; Hulvey, Kimberly D [ORNL

    2007-11-01

    A Retrofit Best Practices Guide was developed to encourage homeowners to consider energy conservation issues whenever they modify their siding or windows. In support of this guide, an experimental program was implemented to measure the performance of a number of possible wall siding and window retrofit configurations. Both thermal and air-leakage measurements were made for a 2.4 x 2.4 m (8 x 8 ft) wall section with and without a 0.9 x 1.2 m (3 x 4 ft) window. The windows tested were previously well-characterized at a dedicated window test facility. A computer model was also used to provide information for the Best Practices Guide. The experimental data for walls and windows were used in conjunction with this model to estimate the total annual energy savings for several typical houses in a number of different locations.

  3. Challenger Center's Window on the Universe

    Science.gov (United States)

    Livengood, T. A.; Goldstein, J. J.; Smith, S.; Bobrowsky, M.; Radnofsky, M.; Perelmuter, J.-M.; Jaggar, L.

    2001-11-01

    Challenger Center for Space Science Education's Window on the Universe program aims to create a network of under-served communities across the nation dedicated to sustained science, math, and technology education. Window communities presently include Broken Arrow, OK; Muncie, IN; Moscow, ID; Nogales, AZ; Tuskegee, AL; Marquette, MI; Altamont, KS; Washington, D.C.; and other emerging sites. Window uses themes of human space flight and the space sciences as interdisciplinary means to inspire entire communities. Practicing scientists and engineers engaged in these disciplines are invited to volunteer to become a part of these communities for a week, each visitor reaching roughly 2000 K-12 students through individual classroom visits and Family Science Night events during an intense Window on the Universe Week. In the same Window Week, Challenger Center scientists and educators present a workshop for local educators to provide training in the use of a K-12 educational module built around a particular space science and exploration theme. Window communities follow a 3-year development: Year 1, join the network, experience Window Week presented by Challenger Center and visiting researchers; Year 2, same as Year 1 plus workshop on partnering with local organizations to develop sources of visiting researchers and to enhance connections with local resources; Year 3 and subsequent, the community stages its own Window Week, with Challenger Center providing new education modules and training workshops for "master educators" from the Window community, after which the master educators return home to conduct training workshops of their own. Challenger Center remains a resource and clearinghouse for Window communities to acquire experience, technical information, and opportunities for distance collaboration with other Window communities. Window on the Universe is dedicated to assessing degree of success vs. failure in each program component and as a whole, using pre- and post

  4. Fabrication Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — The Fabrication Facilities are a direct result of years of testing support. Through years of experience, the three fabrication facilities (Fort Hood, Fort Lewis, and...

  5. Facility Microgrids

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Z.; Walling, R.; Miller, N.; Du, P.; Nelson, K.

    2005-05-01

    Microgrids are receiving a considerable interest from the power industry, partly because their business and technical structure shows promise as a means of taking full advantage of distributed generation. This report investigates three issues associated with facility microgrids: (1) Multiple-distributed generation facility microgrids' unintentional islanding protection, (2) Facility microgrids' response to bulk grid disturbances, and (3) Facility microgrids' intentional islanding.

  6. Hybrid window layer for photovoltaic cells

    Science.gov (United States)

    Deng, Xunming

    2010-02-23

    A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.

  7. Editorial - Opening windows onto data

    Directory of Open Access Journals (Sweden)

    Judith Winters

    2012-05-01

    Full Text Available One of Internet Archaeology's strengths and 'unique selling points' not yet replicated by (many other e-journals, is that data is integrated into articles rather than being 'supplementary' or offered for download. The aim has always been for the narrative to be a wave driving readers towards the underlying data. Opening windows onto the data from within the text is one of the things I think the journal does best and is a feature used throughout Emma Durham's article 'Depicting the gods: metal figurines in Roman Britain'. Archaeological data does not speak for itself. It needs a narrative. It needs context. But by intermeshing data with interpretation, readers can dip into the data and start to explore it while reading the article, allowing a more immediate understanding of the bigger picture.

  8. Waggle Dances and Azimuthal Windows

    Directory of Open Access Journals (Sweden)

    O. Duangphakdee

    2011-01-01

    Full Text Available Because the waggle dances of honeybees contain celestial components, modifications of the dances occur with changing celestial moves relative to a honeybee nest. Since the direction of a particular resource is static, the dances must alter to compensate for the sun's passage. The position of the sun is seasonal between the Tropics of Cancer and Capricorn so that turns at the end of waggle runs will vary with season and latitude. The bees are confronted with a new difficulty when the sun closely approaches its zenith because only slight errors in the bees' estimation of the relative positions of the sun and zenith generate very large errors. So, the sun compass loses its usefulness when at its zenith. We review experiments and observations on both foraging and absconding in relation to the azimuth. The honeybees' solution for the paradox of the azimuth includes an azimuthal lull, preferences, and time windows.

  9. Instant Windows PowerShell

    CERN Document Server

    Menon, Vinith

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. A practical, hands-on tutorial approach that explores the concepts of PowerShell in a friendly manner, taking an adhoc approach to each topic.If you are an administrator who is new to PowerShell or are looking to get a good grounding in these new features, this book is ideal for you. It's assumed that you will have some experience in PowerShell and Windows Server, as well being familiar with the PowerShell command-line.

  10. Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress

    Directory of Open Access Journals (Sweden)

    Roy Polly

    2007-01-01

    Full Text Available Abstract Background The VP2 outer capsid protein Bluetongue Virus (BTV is responsible for receptor binding, haemagglutination and eliciting host-specific immunity. However, the assembly of this outer capsid protein on the transcriptionally active viral core would block transcription of the virus. Thus assembly of the outer capsid on the core particle must be a tightly controlled process during virus maturation. Earlier studies have detected mature virus particles associated with intermediate filaments in virus infected cells but the viral determinant for this association and the effect of disrupting intermediate filaments on virus assembly and release are unknown. Results In this study it is demonstrated that BTV VP2 associates with vimentin in both virus infected cells and in the absence of other viral proteins. Further, the determinants of vimentin localisation are mapped to the N-terminus of the protein and deletions of aminio acids between residues 65 and 114 are shown to disrupt VP2-vimentin association. Site directed mutation also reveals that amino acid residues Gly 70 and Val 72 are important in the VP2-vimentin association. Mutation of these amino acids resulted in a soluble VP2 capable of forming trimeric structures similar to unmodified protein that no longer associated with vimentin. Furthermore, pharmacological disruption of intermediate filaments, either directly or indirectly through the disruption of the microtubule network, inhibited virus release from BTV infected cells. Conclusion The principal findings of the research are that the association of mature BTV particles with intermediate filaments are driven by the interaction of VP2 with vimentin and that this interaction contributes to virus egress. Furthermore, i the N-terminal 118 amino acids of VP2 are sufficient to confer vimentin interaction. ii Deletion of amino acids 65–114 or mutation of amino acids 70–72 to DVD abrogates vimentin association. iii Finally

  11. Windows 7 Annoyances Tips, Secrets, and Solutions

    CERN Document Server

    Karp, David

    2010-01-01

    Windows 7 may be faster and more stable than Vista, but it's a far cry from problem-free. David A. Karp comes to the rescue with the latest in his popular Windows Annoyances series. This thorough guide gives you the tools you need to fix the troublesome parts of this operating system, plus the solutions, hacks, and timesaving tips to make the most of your PC. Streamline Windows Explorer, improve the Search tool, eliminate the Green Ribbon of Death, and tame User Account Control promptsExplore powerful Registry tips and tools, and use them to customize every aspect of Windows and solve its sho

  12. Modelling window opening behaviour in Danish dwellings

    DEFF Research Database (Denmark)

    Andersen, Rune Vinther; Olesen, Bjarne W.; Toftum, Jørn

    2011-01-01

    In this paper we present and analyse data from two studies of window opening behaviour in residential buildings in Denmark. Based on measurements of indoor environment, weather and window opening behaviour in 15 dwellings, we propose a model that will predict window opening behaviour. The data...... showed that other factors than thermal effects impact the behaviour of the occupants. Some of these factors were included in the model. We present data from repeated questionnaire surveys that show that occupants tend to adjust heating setpoints, adjust clothing and operate windows when feeling thermally...

  13. Windows PowerShell 20 Bible

    CERN Document Server

    Lee, Thomas; Schill, Mark E; Tanasovski, Tome

    2011-01-01

    Here's the complete guide to Windows PowerShell 2.0 for administrators and developers Windows PowerShell is Microsoft's next-generation scripting and automation language. This comprehensive volume provides the background that IT administrators and developers need in order to start using PowerShell automation in exciting new ways. It explains what PowerShell is, how to use the language, and specific ways to apply PowerShell in various technologies. Windows PowerShell is Microsoft's standard automation tool and something that every Windows administrator will eventually have to understand; this b

  14. Windows 8.1 for dummies

    CERN Document Server

    Rathbone, Andy

    2013-01-01

    The bestselling book on Windows, now updated for the new 8.1 features Microsoft has fine-tuned Windows 8 with some important new features, and veteran author Andy Rathbone explains every one in this all-new edition of a long-time bestseller. Whether you're using Windows for the first time, upgrading from an older version, or just moving from Windows 8 to 8.1, here's what you need to know. Learn about the dual interfaces, the new Start button, how to customize the interface and boot operations, and how to work with programs and files, use the web and social media, manage music and photos, and

  15. Mastering Windows Server 2008 Networking Foundations

    CERN Document Server

    Minasi, Mark; Mueller, John Paul

    2011-01-01

    Find in-depth coverage of general networking concepts and basic instruction on Windows Server 2008 installation and management including active directory, DNS, Windows storage, and TCP/IP and IPv4 networking basics in Mastering Windows Server 2008 Networking Foundations. One of three new books by best-selling author Mark Minasi, this guide explains what servers do, how basic networking works (IP basics and DNS/WINS basics), and the fundamentals of the under-the-hood technologies that support staff must understand. Learn how to install Windows Server 2008 and build a simple network, security co

  16. The Edge Set Cost of the Vehicle Routing Problem with Time Windows

    DEFF Research Database (Denmark)

    Reinhardt, Line Blander; Jepsen, Mads Kehlet; Pisinger, David

    2016-01-01

    We consider an important generalization of the vehicle routing problem with time windows in which a fixed cost must be paid for accessing a set of edges. This fixed cost could reflect payment for toll roads, investment in new facilities, the need for certifications, and other costly investments...

  17. Measurement of g-value for windows with different solar shading devices

    DEFF Research Database (Denmark)

    Duer, Karsten; Gudum, Charlotte

    1996-01-01

    The resulting g-value (total solar energy transmittance) of windows with different combinations of glazing type and solar shading type is investigated by means of measurements. The measurements are carried out by exposing the indoor test facility (METSET) to sun from the indoor solar simulator (64...

  18. Low-E Storm Windows Gain Acceptance as a Home Weatherization Measure

    Energy Technology Data Exchange (ETDEWEB)

    Gilbride, Theresa L.; Cort, Katherine A.

    2016-05-16

    This article for Home Energy Magazine describes work by the U.S. Department of Energy to develop low-emissivity storm windows as an energy efficiency-retrofit option for existing homes. The article describes the low-emissivity invisible silver metal coatings on the glass, which reflect heat back into the home in winter or back outside in summer and the benefits of low-e storm windows including insulation, air sealing, noise blocking, protection of antique windows, etc. The article also describes Pacific Northwest National Laboratory's efforts on behalf of DOE to overcome market barriers to adoption of the technology, including performance validation studies in the PNNL Lab Homes, cost effectiveness analysis, production of reports, brochures, how-to guides on low-e storm window installation for the Building America Solution Center, and a video posted on YouTube. PNNL's efforts were reviewed by the Pacific Northwest Regional Technical Forum (RTF), which serves as the advisory board to the Pacific Northwest Electric Power Planning Council and Bonneville Power Administration. In late July 2015, the RTF approved the low-e storm window measure’s savings and specifications, a critical step in integrating low-e storm windows into energy-efficiency planning and utility weatherization and incentive programs. PNNL estimates that more than 90 million homes in the United States with single-pane or low-performing double-pane windows would benefit from the technology. Low-e storm windows are suitable not only for private residences but also for small commercial buildings, historic properties, and facilities that house residents, such as nursing homes, dormitories, and in-patient facilities. To further assist in the market transformation of low-e storm windows and other high-efficiency window attachments, DOE helped found the window Attachment Energy Rating Council (AERC) in 2015. AERC is an independent, public interest, non-profit organization whose mission is to rate

  19. Building Management System Using Windows Communication Foundation And XAML

    Directory of Open Access Journals (Sweden)

    Swarnalatha P,

    2011-04-01

    Full Text Available Building Automation System (BAS will be extended for including different kinds of information, working towards to goal of Intelligent Building Management System. The next generation ofInternet technology uses Windows Communication Foundation as middleware technology for integration of different building automation systems (BAS since Web Services will support only http protocol which is stateless. The applications used for controlling building management system (BMS components like sensors, actuators, and controllers. In this paper we propose a Service Oriented Architecture(SOA for building Management system based upon Windows Communication Foundation and XAML used for integrating different BAS.A BAS which consists of BACnet network their BMS is applied. Their exist some publically exposed Windows Communication Foundation contracts, which write and read BACnet data points from the backnet work. These contracts will be called by other enterprise applications for realize BAS integration and get real-time data on BACnet network as a facilities Management. XAML will be provided at client side GUIs for the BMS which can be reused for different kinds of applications.Finally we discuss challenges in providing security to Building Automation Systems using proposed system.

  20. The Nicest way to migrate your Windows computer ( The Windows 2000 Migration Task Force)

    CERN Multimedia

    2001-01-01

    With Windows 2000, CERN users will discover a more stable and reliable working environment and will have access to all the latest applications. The Windows 2000 Migration Task Force - a representative from each division.

  1. Glass-windowed ultrasound transducers.

    Science.gov (United States)

    Yddal, Tostein; Gilja, Odd Helge; Cochran, Sandy; Postema, Michiel; Kotopoulis, Spiros

    2016-05-01

    In research and industrial processes, it is increasingly common practice to combine multiple measurement modalities. Nevertheless, experimental tools that allow the co-linear combination of optical and ultrasonic transmission have rarely been reported. The aim of this study was to develop and characterise a water-matched ultrasound transducer architecture using standard components, with a central optical window larger than 10 mm in diameter allowing for optical transmission. The window can be used to place illumination or imaging apparatus such as light guides, miniature cameras, or microscope objectives, simplifying experimental setups. Four design variations of a basic architecture were fabricated and characterised with the objective to assess whether the variations influence the acoustic output. The basic architecture consisted of a piezoelectric ring and a glass disc, with an aluminium casing. The designs differed in piezoelectric element dimensions: inner diameter, ID=10 mm, outer diameter, OD=25 mm, thickness, TH=4 mm or ID=20 mm, OD=40 mm, TH=5 mm; glass disc dimensions OD=20-50 mm, TH=2-4 mm; and details of assembly. The transducers' frequency responses were characterised using electrical impedance spectroscopy and pulse-echo measurements, the acoustic propagation pattern using acoustic pressure field scans, the acoustic power output using radiation force balance measurements, and the acoustic pressure using a needle hydrophone. Depending on the design and piezoelectric element dimensions, the resonance frequency was in the range 350-630 kHz, the -6 dB bandwidth was in the range 87-97%, acoustic output power exceeded 1 W, and acoustic pressure exceeded 1 MPa peak-to-peak. 3D stress simulations were performed to predict the isostatic pressure required to induce material failure and 4D acoustic simulations. The pressure simulations indicated that specific design variations could sustain isostatic pressures up to 4.8 MPa.The acoustic simulations were able to

  2. Automatic Water Sensor Window Opening System

    KAUST Repository

    Percher, Michael

    2013-12-05

    A system can automatically open at least one window of a vehicle when the vehicle is being submerged in water. The system can include a water collector and a water sensor, and when the water sensor detects water in the water collector, at least one window of the vehicle opens.

  3. Windows Azure Blob Storage来存储Windows Phone App数据%To Store Windows Phone App Data using Windows Azure Blob Storage

    Institute of Scientific and Technical Information of China (English)

    高建

    2015-01-01

    Cloud computing and storage is replacing the traditional web site hosting, while mobile phone application is getting used by more people. There are several different cloud computing solutions and different mobile phone operating system. Microsoft’s cloud platform is Windows Azure, while its mobile phone operating system is Windows Phone. How to store Windows Phone App data in Windows Azure Blob Storage is discussed in this paper.%云计算和云存储正在替代以前的网站和应用空间,而手机APP正比桌面软件占用人们更多的访问数据和信息的时间,现在有不同的云服务和手机应用平台。微软公司的云服务平台为Windows Azure,其手机操作系统为Windows Phone,探讨了如何用Windows Azure Blob Storage来存储Windows Phone App的数据。

  4. Thermal Bridge Effects in Window Grooves

    DEFF Research Database (Denmark)

    Rose, Jørgen

    1997-01-01

    In this report thermal bridge effects in window grooves are analyzed. The analysis is performed using different thicknesses of the window groove insulation, to evaluate what the optimal solution is.All analysis in the report is performed using both 2- and 3-dimensional numerical analysis....

  5. Measured Rattle Threshold of Residential House Windows

    Science.gov (United States)

    Sizov, Natalia; Schultz, Troy; Hobbs, Christopher; Klos, Jacob

    2008-01-01

    Window rattle is a common indoor noise effect in houses exposed to low frequency noise from such sources as railroads, blast noise and sonic boom. Human perception of rattle can be negative that is a motivating factor of the current research effort to study sonic boom induced window rattle. A rattle study has been conducted on residential houses containing windows of different construction at a variety of geographic locations within the United States. Windows in these houses were excited by a portable, high-powered loudspeaker and enclosure specifically designed to be mounted on the house exterior to cover an entire window. Window vibration was measured with accelerometers placed on different window components. Reference microphones were also placed inside the house and inside of the loudspeaker box. Swept sine excitation was used to identify the vibration threshold at which the response of the structure becomes non-linear and begins to rattle. Initial results from this study are presented and discussed. Future efforts will continue to explore the rattle occurrence in windows of residential houses exposed to sonic booms.

  6. Tactical/Combat Engines Cetane Window Evaluation

    Science.gov (United States)

    2013-01-31

    custom diesel fuels typically used in Homogeneous Charge Coupled Ignition ( HCCI ) research engines . These fuels are characterized by a very heavy...UNCLASSIFIED TACTICAL/COMBAT ENGINES CETANE WINDOW EVALUATION INTERIM REPORT TFLRF No. 436 by Gregory A. Hansen, Douglas Yost...report when no longer needed. Do not return it to the originator. UNCLASSIFIED UNCLASSIFIED TACTICAL/COMBAT ENGINES CETANE WINDOW

  7. Humeral windows in revision total elbow arthroplasty

    Science.gov (United States)

    Salama, Amir; Stanley, David

    2016-01-01

    The use of cortical windows for revision elbow arthroplasty has not previously been widely reported. Their use aids safe revision of a well fixed humeral prosthesis and can be used in the setting of dislocation, periprosthetic fracture or aseptic loosening of the ulnar component. We describe our technique and results of cortical windows in the distal humerus for revision elbow arthroplasty surgery. PMID:27583011

  8. Measure Guideline: Window Repair, Rehabilitation, and Replacement

    Energy Technology Data Exchange (ETDEWEB)

    Baker, P.

    2012-12-01

    This measure guideline provides information and guidance on rehabilitating, retrofitting, and replacing existing window assemblies in residential construction. The intent is to provide information regarding means and methods to improve the energy and comfort performance of existing wood window assemblies in a way that takes into consideration component durability, in-service operation, and long term performance of the strategies.

  9. Location of an acoustic window in dolphins.

    Science.gov (United States)

    Popov, V V; Supin, A Y

    1990-01-15

    Auditory brainstem responses (ABR) to sound clicks from sources in different positions were recorded in dolphins Inia geoffrensis. The position of the acoustic window was determined by measurement of acoustic delays. The acoustic window was found to lie close to the auditory meatus and the bulla rather than on the lower jaw.

  10. What are windows on language evolution?

    NARCIS (Netherlands)

    Botha, Rudolf

    This chapter offers an elucidation of the idea that certain phenomena provide windows on language evolution. Non-metaphorically, such windows are shown to be conceptual constructs used for making inferences about aspects of language evolution from data or assumptions about properties of

  11. Characteristics of Air Flow through Windows

    DEFF Research Database (Denmark)

    Heiselberg, Per; Dam, Henrik; Sørensen, Lars C.

    This paper describes the first results of a series of laboratory investigations that is performed to characterise three different window types. The results show the air flow conditions for different ventilation strategies and temperature differences. For one of the windows values of the discharge...

  12. Supporting Multiple Pointing Devices in Microsoft Windows

    DEFF Research Database (Denmark)

    Westergaard, Michael

    2002-01-01

    In this paper the implementation of a Microsoft Windows driver including APIs supporting multiple pointing devices is presented. Microsoft Windows does not natively support multiple pointing devices controlling independent cursors, and a number of solutions to this have been implemented by us...

  13. European energy labelling scheme for windows

    Energy Technology Data Exchange (ETDEWEB)

    Belling Skou, Mette (VELUX A/S (Denmark)); Kragh, Jesper (DTU Byg, Denmarks Tekniske Univ., Lyngby (Denmark))

    2009-07-01

    In their proposals for revision of the energy labelling directive the European Commission has suggested to include windows. The paper introduces a proposal for an European energy labelling scheme of windows for replacement of windows in the existing building stock taking into consideration the energy performance of windows in both the heating and cooling seasons. The labelling scheme evaluates a methodology where the energy performance in the heating period is established with focus on heat loss and utilization of passive solar energy, whereas the energy performance in the summer (cooling) season will focus on reduction of solar radiation into the building. The methodology is developed with focus on CEN and ISO standardization. With inspiration from the American Energy Star programme for windows, Europe is divided into climate zones where the methodology for each zone is developed on basis of a reference building and climate data. A proposal for labelling will be presented for both heating and cooling seasons in order to enable the user to choose the right product for a specific performance. Based on data from the building stock in the individual climate zones, an energy saving potential for replacement of old windows with new low energy windows will be presented. The possibility for using energy labelling of windows as reference and requirement in the building legislation as an alternative to U-values, will be presented with among others examples from legislation in UK and Denmark.

  14. Supporting Multiple Pointing Devices in Microsoft Windows

    DEFF Research Database (Denmark)

    Westergaard, Michael

    2002-01-01

    In this paper the implementation of a Microsoft Windows driver including APIs supporting multiple pointing devices is presented. Microsoft Windows does not natively support multiple pointing devices controlling independent cursors, and a number of solutions to this have been implemented by us...

  15. Proton irradiation damage of an annealed Alloy 718 beam window

    Science.gov (United States)

    Bach, H. T.; Anderoglu, O.; Saleh, T. A.; Romero, T. J.; Kelsey, C. T.; Olivas, E. R.; Sencer, B. H.; Dickerson, P. O.; Connors, M. A.; John, K. D.; Maloy, S. A.

    2015-04-01

    Mechanical testing and microstructural analysis was performed on an Alloy 718 window that was in use at the Los Alamos Neutron Science Center (LANSCE) Isotope Production Facility (IPF) for approximately 5 years. It was replaced as part of the IPF preventive maintenance program. The window was transported to the Wing 9 hot cells at the Chemical and Metallurgical Research (CMR) LANL facility, visually inspected and 3-mm diameter samples were trepanned from the window for mechanical testing and microstructural analysis. Shear punch testing and optical metallography was performed at the CMR hot cells. The 1-mm diameter shear punch disks were cut into smaller samples to further reduce radiation exposure dose rate using Focus Ion Beam (FIB) and microstructure changes were analyzed using a Transmission Electron Microscopy (TEM). Irradiation doses were determined to be ∼0.2-0.7 dpa (edge) to 11.3 dpa (peak of beam intensity) using autoradiography and MCNPX calculations. The corresponding irradiation temperatures were calculated to be ∼34-120 °C with short excursion to be ∼47-220 °C using ANSYS. Mechanical properties and microstructure analysis results with respect to calculated dpa and temperatures show that significant work hardening occurs but useful ductility still remains. The hardening in the lowest dose region (∼0.2-0.7 dpa) was the highest and attributed to the formation of γ″ precipitates and irradiation defect clusters/bubbles whereas the hardening in the highest dose region (∼11.3 dpa) was lower and attributed mainly to irradiation defect clusters and some thermal annealing.

  16. Android is the new Windows

    CERN Multimedia

    Computer Security Team

    2013-01-01

    Do you recall the early virus attacks in the early 2000s? “Blaster”, “I love you” and “Slammer” were attacking the pretty much unprotected Microsoft Windows operating system.   While Microsoft has been hit hard in the past, they have tried to improve and are now on a par with other software vendors. Today, they can even be happy that Android is taking over the baton - at least on mobile platforms. According to the Sophos 2013 Security Threat Report “Android [is] today’s the biggest target” and Android devices in Australia and the U.S. experienced even more malware attacks, whether successful or unsuccessful, than PCs during the past three months. The Kaspersky security company recently added that 99% of all mobile threats target Android. Lucky you if you use an iPhone, or a good old Nokia with no Internet connectivity at all. But why is that? It is partly down to the same fac...

  17. AGB variables in Baade's windows

    CERN Document Server

    Schultheis, M

    2001-01-01

    In this work, a sample of luminous M-type giants in the Baade's Windows towards the inner Galactic Bulge is investigated in the near-infrared. The ISOGAL survey at 7 and 15 micron has given information concerning the mass-loss rates of these stars and their variability characteristics have been extracted from the MACHO database. Most are known to be semi-regular variables (SRVs). Here we discuss how their IJHK-region colours depend on period and the presence or absence of mass-loss, using results mainly taken from the DENIS and 2MASS surveys. In order to compare their colours with solar neighbourhood stars, photometric colours on the DENIS, 2MASS and ESO photometric systems have been synthesized for objects in the spectrophotometric atlas of Lancon and Wood (2000). In addition, they have been used to predict the differences in colour indicies when stars with strong molecular bands are observed using different photometric systems. The SRVs are found to inhabit the upper end of the J-K, K colour-magnitude diagr...

  18. How to Green Windows Update?

    Directory of Open Access Journals (Sweden)

    Seifedine Kadry

    2012-11-01

    Full Text Available The most important challenges facing the earth in the future are energy, water, environment and food security, Green IT contributes in significant role in finding solutions because it consume energy more efficient and reduce pollution in water, air and soil in addition to improving economy because Green IT is manage energy sources by reducing energy consumption with good performance. Most of energy consumed around the world depends on non-renewable energy and part of this energy consumed to update technologies In this paper ,we will study one of the most important tools in Microsoft, which is used in order to help users to get updates of Microsoft's products, which is called windows server update services (WSUS, which is helping to reduce energy consumption, we will study this tool and then try to make it more green by reducing the send / receive between Microsoft Update (MU and WSUS, which will reduce energy consumption, and we will propose algorithm and compared the energy consumption in the current design with energy consumption in the proposed design. This design will open the way for future work in order to make sending updates in MU less energy consumption by apply conditional sending and that will help to improve the performance of MU added to improve the network performance with more efficient consumption of energy.

  19. Least Squares Moving-Window Spectral Analysis.

    Science.gov (United States)

    Lee, Young Jong

    2017-01-01

    Least squares regression is proposed as a moving-windows method for analysis of a series of spectra acquired as a function of external perturbation. The least squares moving-window (LSMW) method can be considered an extended form of the Savitzky-Golay differentiation for nonuniform perturbation spacing. LSMW is characterized in terms of moving-window size, perturbation spacing type, and intensity noise. Simulation results from LSMW are compared with results from other numerical differentiation methods, such as single-interval differentiation, autocorrelation moving-window, and perturbation correlation moving-window methods. It is demonstrated that this simple LSMW method can be useful for quantitative analysis of nonuniformly spaced spectral data with high frequency noise.

  20. A monolithic thin film electrochromic window

    Energy Technology Data Exchange (ETDEWEB)

    Goldner, R.B.; Arntz, F.O.; Berera, G.; Haas, T.E.; Wong, K.K. (Tufts Univ., Medford, MA (United States). Electro-Optics Technology Center); Wei, G. (Mobil Solar Energy Corp., Billerica, MA (United States)); Yu, P.C. (PPG Industries, Inc., Monroeville, PA (United States))

    1991-01-01

    Three closely related thin film solid state ionic devices that are potentially important for applications are: electrochromic smart windows, high energy density thin film rechargeable batteries, and thin film electrochemical sensors. Each usually has at least on mixed ion/electron conductor, an electron-blocking ion conductor, and an ion-blocking electron conductor, and many of the technical issues associated with thin film solid state ionics are common to all three devices. Since the electrochromic window has the added technical requirement of electrically-controlled optical modulation, (over the solar spectrum), and since research at the authors' institution has focused primarily on the window structure, this paper will address the electrochromic window, and particularly a monolithic variable reflectivity electrochromic window, as an illustrative example of some of the challenges and opportunities that are confronting the thin film solid state ionics community. 33 refs.

  1. A monolithic thin film electrochromic window

    Energy Technology Data Exchange (ETDEWEB)

    Goldner, R.B.; Arntz, F.O.; Berera, G.; Haas, T.E.; Wong, K.K. [Tufts Univ., Medford, MA (United States). Electro-Optics Technology Center; Wei, G. [Mobil Solar Energy Corp., Billerica, MA (United States); Yu, P.C. [PPG Industries, Inc., Monroeville, PA (United States)

    1991-12-31

    Three closely related thin film solid state ionic devices that are potentially important for applications are: electrochromic smart windows, high energy density thin film rechargeable batteries, and thin film electrochemical sensors. Each usually has at least on mixed ion/electron conductor, an electron-blocking ion conductor, and an ion-blocking electron conductor, and many of the technical issues associated with thin film solid state ionics are common to all three devices. Since the electrochromic window has the added technical requirement of electrically-controlled optical modulation, (over the solar spectrum), and since research at the authors` institution has focused primarily on the window structure, this paper will address the electrochromic window, and particularly a monolithic variable reflectivity electrochromic window, as an illustrative example of some of the challenges and opportunities that are confronting the thin film solid state ionics community. 33 refs.

  2. Window company standardizes low-E glass

    Energy Technology Data Exchange (ETDEWEB)

    Trombly, J.

    Anderson Corporation announced in late 1989 that it would be standardizing low-emissivity (low-E) glass in all of its products, except the gliding windows and the basement/storm windows, starting in 1990. In addition, all its High-Performance glass ordered this year will automatically feature the argon gas filling between panes. (Filling the space between two glass panes with argon rather than air reduces the heat conduction of the window.) Low-E windows are glazed with a coating that bonds a microscopic, transparent, metallic substance to the inside surface of the double-pane windows, cutting down on the emission of long-wave infrared light, thereby reducing heat loss.

  3. Windows 8 app projects XAML and C#

    CERN Document Server

    Vermeir, Nico

    2013-01-01

    Become a leading Windows 8 app developer by using Windows 8 App Projects - XAML and C# Edition to learn techniques, tools, and ideas to create successful, 5-star apps. Windows 8 App Projects - XAML and C# Edition shows you the nuts and bolts of the Windows 8 development ecosystem. Then, through a series of example driven chapters, you'll discover how to leverage the platform's unique features. With each project, you'll be one step closer to building full-featured, responsive, and well designed apps that feel like they're a part of the operating system. Windows 8 App Projects - XAML and C# Edit

  4. Mastering Windows Server 2012 R2

    CERN Document Server

    Minasi, Mark; Booth, Christian; Butler, Robert; McCabe, John; Panek, Robert; Rice, Michael; Roth, Stefan

    2013-01-01

    Check out the new Hyper-V, find new and easier ways to remotely connect back into the office, or learn all about Storage Spaces-these are just a few of the features in Windows Server 2012 R2 that are explained in this updated edition from Windows authority Mark Minasi and a team of Windows Server experts led by Kevin Greene. This book gets you up to speed on all of the new features and functions of Windows Server, and includes real-world scenarios to put them in perspective. If you're a system administrator upgrading to, migrating to, or managing Windows Server 2012 R2, find what you need to

  5. Significant performance enhancement of yttrium-doped barium cerate proton conductor as electrolyte for solid oxide fuel cells through a Pd ingress-egress approach

    Science.gov (United States)

    Liu, Yu; Ran, Ran; Li, Sidian; Jiao, Yong; Tade, Moses O.; Shao, Zongping

    2014-07-01

    Proton-conducting perovskite oxides are excellent electrolyte materials for SOFCs that may improve power density at reduced temperatures and increase fuel efficiency, thus encouraging the widespread implementation of this attractive technology. The main challenges in the application of these oxides in SOFCs are difficult sintering and insufficient conductivity in real cells. In this study, we propose a novel method to significantly enhance the performance of a yttrium-doped barium cerate proton conductor as an electrolyte for SOFCs through a Pd ingress-egress approach to the development of BaCe0.8Y0.1Pd0.1O3-δ (BCYP10). The capability of the Pd egress from the BCYP10 perovskite lattice is demonstrated by H2-TPR, XRD, EDX mapping of STEM and XPS. Significant improvement in the sinterability is observed after the introduction of Pd due to the increased ionic conductivity and the sintering aid effect of egressed Pd. The formation of a B-site cation defect structure after Pd egress and the consequent modification of perovskite grain boundaries with Pd nanoparticles leads to a proton conductivity of BCYP10 that is approximately 3 times higher than that of BCY under a reducing atmosphere. A single cell with a thin film BCYP10 electrolyte reaches a peak power density as high as 645 mA cm-2 at 700 °C.

  6. Applying State-of-the-Art Technologies to Reduce Escape Times from Fires Using Environmental Sensing, Improved Occupant Egress Guidance, and Multiple Communication Protocols

    Science.gov (United States)

    2009-02-06

    that could monitor sensors, evaluate environmental 4 conditions, and control visual and sound devices was conducted. The home automation products used...the prototype system. Use of off-the-shelf home automation products allowed the implementation of an egress control prototype suitable for test and

  7. Efficient Adjustable Reflectivity Smart Window

    Energy Technology Data Exchange (ETDEWEB)

    D. Morgan Tench

    2005-12-01

    This project addressed the key technical issues for development of an efficient smart window based on reversible electrochemical transfer of silver between a mirror electrode and a localized counter electrode. Effort to provide uniform switching over large areas focused on use of a resistive transparent electrode innerlayer to increase the interelectrode resistance. An effective edge seal was developed in collaboration with adhesive suppliers and an electrochromic device manufacturer. Work to provide a manufacturable counter electrode focused on fabricating a dot matrix electrode without photolithography by electrodeposition of Pt nuclei on inherent active sites on a transparent oxide conductor. An alternative counter electrode based on a conducting polymer and an ionic liquid electrolyte was also investigated. Work in all of these areas was successful. Sputtered large-bandgap oxide innerlayers sandwiched between conductive indium tin oxide (ITO) layers were shown to provide sufficient cross-layer resistance (>300 ohm/cm{sup 2}) without significantly affecting the electrochemical properties of the ITO overlayer. Two edge seal epoxies, one procured from an epoxy manufacturer and one provided by an electrochromic device manufacturer in finished seals, were shown to be effective barriers against oxygen intrusion up to 80 C. The optimum density of nuclei for the dot matrix counter electrode was attained without use of photolithography by electrodeposition from a commercial alkaline platinum plating bath. Silver loss issues for cells with dot matrix electrodes were successfully addressed by purifying the electrolyte and adjusting the cell cycling parameters. More than 30K cycles were demonstrated for a REM cell (30-cm square) with a dot matrix counter electrode. Larger cells (30-cm square) were successfully fabricated but could not be cycled since the nucleation layers (provided by an outside supplier) were defective so that mirror deposits could not be produced.

  8. AN INTRODUCTION TO WINDOWS 2000 AT CERN

    CERN Multimedia

    2001-01-01

    A demonstration of the new supported Windows environment for all the CERN personal computers (PC) will be given which is based on Windows 2000. This presentation will assume little or no familiarity with the PC, or NICE, and will concentrate on the services being offered to the users of PCs at CERN. How NICE 2000 can facilitate the work of all users, eventually becoming the key access point to all activities in the laboratory will be demonstrated. Date Title Language Location Speaker Fri 1/6 10:00 Une introduction à Windows 2000 au CERN F IT Auditorium (31/3-004) Alberto Pace Tue 5/6 10:00 Une introduction à Windows 2000 au CERN F LHC Auditorium (30/7th floor) Frederic Hemmer Tue 5/6 14:00 Une introduction à Windows 2000 au CERN F SL Auditorium (864/1s floor) Michel Bornand Tue 5/6 14:00 An introduction to Windows 2000 at CERN E IT Auditorium (31/3-004) Andreas Wagner Wed 6/6 14:00 Une introduction à Windows 2000 au CERN F SL ...

  9. Identification of Protective B-Cell Epitopes within the Novel Malaria Vaccine Candidate Plasmodium falciparum Schizont Egress Antigen 1.

    Science.gov (United States)

    Nixon, Christina E; Park, Sangshin; Pond-Tor, Sunthorn; Raj, Dipak; Lambert, Lynn E; Orr-Gonzalez, Sachy; Barnafo, Emma K; Rausch, Kelly M; Friedman, Jennifer F; Fried, Michal; Duffy, Patrick E; Kurtis, Jonathan D

    2017-07-01

    Naturally acquired antibodies to Plasmodium falciparum schizont egress antigen 1 (PfSEA-1A) are associated with protection against severe malaria in children. Vaccination of mice with SEA-1A from Plasmodium berghei (PbSEA-1A) decreases parasitemia and prolongs survival following P. berghei ANKA challenge. To enhance the immunogenicity of PfSEA-1A, we identified five linear B-cell epitopes using peptide microarrays probed with antisera from nonhuman primates vaccinated with recombinant PfSEA-1A (rPfSEA-1A). We evaluated the relationship between epitope-specific antibody levels and protection from parasitemia in a longitudinal treatment-reinfection cohort in western Kenya. Antibodies to three epitopes were associated with 16 to 17% decreased parasitemia over an 18-week high transmission season. We are currently designing immunogens to enhance antibody responses to these three epitopes. Copyright © 2017 American Society for Microbiology.

  10. Pilot Field Test: The Ability to Ambulate Following Landing as Assessed with Seat Egress, Walk and Obstacle Testing

    Science.gov (United States)

    Fisher, E. A.; Fomina, E. V; Reschke, M. F.; Cerisano, J. M.; Kofman, I. S.; Gadd, N. E.; Phillips, T. R.; Lee, S. M. C.; Laurie, S. S.; Stenger, M. B.; Bloomberg, J. J.; Mulavara, A. P.; Kozlovskaya, I. B.; Tomilovskaya, E. S.

    2016-01-01

    To date, changes in functional performance have been systematically studied after short-duration space flight. As important as the postflight functional changes have been, full functional recovery has never been investigated or established for long-duration flights. The Pilot Field Test (PFT) experiment, conducted with participation of ISS crewmembers traveling on Soyuz expeditions 34S - 41S, is comprised of several tasks designed to study the recovery of sensorimotor abilities of astronauts during the first 24 hours after landing and beyond. The objective of the Seat Egress - Walk and Obstacle Test, developed by NASA's Russian collaborators at the Institute for Biomedical Problems, is to address this gap in knowledge. This will allow us to characterize the ability of crewmembers to perform critical mission requirements that they will be expected to perform after an unassisted landing following 6 to 12 months in microgravity.

  11. Inactivation of retinoblastoma protein does not overcome the requirement for human cytomegalovirus UL97 in lamina disruption and nuclear egress.

    Science.gov (United States)

    Reim, Natalia I; Kamil, Jeremy P; Wang, Depeng; Lin, Alison; Sharma, Mayuri; Ericsson, Maria; Pesola, Jean M; Golan, David E; Coen, Donald M

    2013-05-01

    Human cytomegalovirus (HCMV) encodes one conventional protein kinase, UL97. During infection, UL97 phosphorylates the retinoblastoma tumor suppressor protein (pRb) on sites ordinarily phosphorylated by cyclin-dependent kinases (CDK), inactivating the ability of pRb to repress host genes required for cell cycle progression to S phase. UL97 is important for viral DNA synthesis in quiescent cells, but this function can be replaced by human papillomavirus type 16 E7, which targets pRb for degradation. However, viruses in which E7 replaces UL97 are still defective for virus production. UL97 is also required for efficient nuclear egress of viral nucleocapsids, which is associated with disruption of the nuclear lamina during infection, and phosphorylation of lamin A/C on serine 22, which antagonizes lamin polymerization. We investigated whether inactivation of pRb might overcome the requirement of UL97 for these roles, as pRb inactivation induces CDK1, and CDK1 phosphorylates lamin A/C on serine 22. We found that lamin A/C serine 22 phosphorylation during HCMV infection correlated with expression of UL97 and was considerably delayed in UL97-null mutants, even when E7 was expressed. E7 failed to restore gaps in the nuclear lamina seen in wild-type but not UL97-null virus infections. In electron microscopy analyses, a UL97-null virus expressing E7 was as impaired as a UL97-null mutant in cytoplasmic accumulation of viral nucleocapsids. Our results demonstrate that pRb inactivation is insufficient to restore efficient viral nuclear egress of HCMV in the absence of UL97 and instead argue further for a direct role of UL97 in this stage of the infectious cycle.

  12. Microsoft Windows Server 2012 administration instant reference

    CERN Document Server

    Hester, Matthew

    2013-01-01

    Fast, accurate answers for common Windows Server questions Serving as a perfect companion to all Windows Server books, this reference provides you with quick and easily searchable solutions to day-to-day challenges of Microsoft's newest version of Windows Server. Using helpful design features such as thumb tabs, tables of contents, and special heading treatments, this resource boasts a smooth and seamless approach to finding information. Plus, quick-reference tables and lists provide additional on-the-spot answers. Covers such key topics as server roles and functionality, u

  13. Teach yourself visually Windows 8 tablets

    CERN Document Server

    McFedries, Paul

    2012-01-01

    A visual guide to all the features of the new Windows 8 Tablet This must-have resource features visually rich, step-by-step instructions that show you how to get the most enjoyment from your Windows 8 tablet. Learn about the exciting new Metro UI, optimized specifically for touch devices. The most popular and commonly used apps and functions are covered too, along with the basics of syncing with a network, setting up e-mail, watching videos, listening to music, and common productivity tasks. This book provides all the guidance needed to enjoy all the best the new Windows 8 tablets have to offe

  14. Probabilistic fault localization with sliding windows

    Institute of Scientific and Technical Information of China (English)

    ZHANG Cheng; LIAO JianXin; LI TongHong; ZHU XiaoMin

    2012-01-01

    Fault localization is a central element in network fault management.This paper takes a weighted bipartite graph as a fault propagation model and presents a heuristic fault localization algorithm based on the idea of incremental coverage,which is resilient to inaccurate fault propagation model and the noisy environment.Furthermore,a sliding window mechanism is proposed to tackle the inaccuracy of this algorithm in the presence of improper time windows.As shown in the simulation study,our scheme achieves higher detection rate and lower false positive rate in the noisy environment as well as in the presence of inaccurate windows,than current fault localization algorithms.

  15. Windows PowerShell Quick Reference

    CERN Document Server

    Holmes, Lee

    2006-01-01

    For years, support for scripting and command-line administration on the Windows platform has paled in comparison to the support offered by the Unix platform. Unix administrators enjoyed the immense power and productivity of their command shells, while Windows administrators watched in envy. Windows PowerShell, Microsoft's next-generation command shell and scripting language, changes this landscape completely. This Short Cut contains the essential reference material to help you get your work done-including the scripting language syntax, a regular-expression reference, useful .NET classes, an

  16. Windows 8 & Office 2010 for dummies

    CERN Document Server

    Rathbone, Andy

    2012-01-01

    Two complete e-books covering Windows and Office for one low price! This unique value-priced e-book set brings together two bestselling For Dummies books in a single e-book file. Including a comprehensive table of contents and the full text of each book, complete with cover, this e-book set gives you in-depth information on the leading PC productivity tools: Windows 8 and Office 2010. Best of all, you'll pay less than the cost of each book purchased separately. You'll get the complete text of: Windows 8 For Dummies, which covers The core component

  17. Window Shopping, Granada, 1930s”

    Directory of Open Access Journals (Sweden)

    Mae Claxton

    2010-02-01

    Full Text Available “Window Shopping, Granada, 1930s,” Photographs, p. 16, with the gracious permission of the Eudora Welty FoundationAn African American woman, dressed in her Saturday go-to-town-best, stands outside a store window, chin in hand, contemplating the contents in the window. The image is reflective and thoughtful. What is she thinking? And what lies beyond the frame of this photograph? In Mississippi in the 1930s, could she walk into this store, perhaps try on clothes or hats, and make a purchase? I...

  18. Windows Server 2012 ja Active Directory

    OpenAIRE

    2015-01-01

    Opinnäytetyön aiheena oli tutustua Windows Server 2012–ohjelmiston sisältämiin palveluihin sekä perehtyä tarkemmin Active Directoryn peruskäyttöön. Tavoitteena oli antaa lukijalle ymmärrys Windows Server 2012–ohjelmiston tarjoamista käyttömahdollisuuksista ja Active Directoryn käytöstä. Opinnäytetyön tietoperusta koostui virtuaaliympäristön käytöstä ja erilaisista Windows Server 2012–ohjelman palveluista. Tietoperusta kattoi esimerkiksi seuraavat käsitteet: Virtuaalisointi, Emulointi, Ohj...

  19. Managing customer arrivals with time windows

    DEFF Research Database (Denmark)

    Chen, Gang; Jiang, Liping

    2016-01-01

    Due to increasing container traffic and mega-ships, many seaports face challenges of huge amounts of truck arrivals and congestion problem at terminal gates, which affect port efficiency and generate serious air pollution. To solve this congestion problem, we propose a solution of managing truck...... arrivals with time windows based on the truck-vessel service relationship, specifically trucks delivering containers for the same vessel share one common time window. Time windows can be optimized with different strategies. In this paper, we first propose a framework for installing this solution...

  20. CSS for Windows 8 app development

    CERN Document Server

    Foster, Jeremy

    2013-01-01

    CSS for Windows 8 App Development is your learning guide for CSS - the language of great Windows 8-style apps. Learn the built-in styles that make the built-in controls shine, how to define them, and how to use CSS to give your custom app assets that beautiful Modern UI style. CSS (Cascading Style Sheets) is the clear standard for styling web applications, and with HTML, CSS, and JavaScript now powering apps on Windows 8, it's the clear standard there as well. CSS is a powerful styling and layout language that greatly simplifies the selection of page elements and their visual display, layout,

  1. Broadband, ultralow reflectance surface structures on silica windows for high-energy laser applications (Conference Presentation)

    Science.gov (United States)

    Busse, Lynda E.; Frantz, Jesse A.; Shaw, L. Brandon; Poutous, Menelaos K.; Aggarwal, Ishwar D.; Sanghera, Jasbinder S.

    2017-05-01

    The characteristics of broadband transmission, environmental durability, and laser damage resistance are critical for silica glass exit aperture windows for their use in kW-level, high energy laser systems. The use of conventional antireflective (AR) coatings on windows for high energy lasers operating in the near infrared is impacted by laser induced damage that occurs under high power irradiation as well as the potential for delamination in operational environments. Novel methods for fabricating antireflective surface structures (ARSS) directly on optics have resulted not only in reduced reflection loss, but also in other advantages to AR coatings as well. The ARSS approach involves sub-wavelength surface structures fabricated directly into the actual surface of the window, eliminating the need for a coating of extraneous materials. We will report on results for ARSS fabricated on silica glass windows. Recently we have reported broadband, low reflectance (laser damage thresholds of 100 J/cm2 at 1.06 µm, which is 5x the threshold measured for a conventional AR coating. We will also present results for MILSPEC durability tests on silica windows, both with and without ARSS, for rain and sand erosion as well as salt fog testing, conducted at a government facility. We will also report on scale up of ARSS on silica windows of large sizes (33 cm), making them practical for system implementation.

  2. A composite thin vacuum window for the CLAS photon tagger at Jefferson lab

    CERN Document Server

    Matthews, S K; O'Brien, J T; Sober, D I

    1999-01-01

    The construction of a thin vacuum window, currently in use on the CLAS photon tagging system at the Thomas Jefferson National Accelerator Facility, is described. A layer of woven Kevlar cloth supports a much thinner membrane of aluminized Mylar. Notable features of this particular window include its overall length (9.6 m), and the fact that the entire load is supported by the epoxy seal with no mechanical clamping around the edges. Results from a diverse program of materials testing, including a clear dependence of leak rate on relative humidity, are also reported.

  3. Windows 10其他功能

    Institute of Scientific and Technical Information of China (English)

    王春海

    2015-01-01

    本文介绍Windows10的一些其他功能,这包括新添加的“3DBuilder”、WindowsHello登录界面、Windows To Go功能等。3DBuiIder功能在Windows10中,提供的“3DBuilder”功能,包括了3D模型库,内置了类似Word图案的基本3D图形,包括圆球、圆柱、圆锥、圆环、立方体、火车、飞机等图形(如图1)。

  4. A NOVEL METHOD ON DESIGNING BISPECTRAL WINDOWS

    Institute of Scientific and Technical Information of China (English)

    YaoWenbing; YaoTianren; 等

    2002-01-01

    A novel method on designing bispectral windows is proposed in this letter.Com-pound functions based on a function with binary quadric form,starting from the symmetry characteristic of three-order moments are used as the 2-D window functions.Two approaches on how to find the expressions of the compound functions are discussed in detail.One is to approxi-mate the compound function after being Taylor expanded under the MinimumMean Square Error (MMSE)criteria.Another is to compound the hyperbolic secant function and the binary quadric function directly.According to theoretical analysis,the first type new windows have been proved as slightly better than the conventional ones,the second type new windows are much better than the conventional ones ,and the bispectral estimation mean square error approximates to 0.

  5. Temporal Analysis of Windows MRU Registry Keys

    Science.gov (United States)

    Zhu, Yuandong; Gladyshev, Pavel; James, Joshua

    The Microsoft Windows registry is an important resource in digital forensic investigations. It contains information about operating system configuration, installed software and user activity. Several researchers have focused on the forensic analysis of the Windows registry, but a robust method for associating past events with registry data values extracted from Windows restore points is not yet available. This paper proposes a novel algorithm for analyzing the most recently used (MRU) keys found in consecutive snapshots of the Windows registry. The algorithm compares two snapshots of the same MRU key and identifies data values within the key that have been updated in the period between the two snapshots. User activities associated with the newly updated data values can be assumed to have occurred during the period between the two snapshots.

  6. Translational nanomedicine--through the therapeutic window.

    Science.gov (United States)

    Pierce, Robin L

    2015-01-01

    Translational nanomedicine occurs only through the successful integration of multiple inputs and iterative modifications. The therapeutic window plays a pivotal role in the trajectory of translational nanomedicine. Often defined in terms of the range of dosage for safe and effective therapeutic effect, a second definition of the therapeutic window refers to the often narrow temporal window in which a therapeutic effect can be obtained. Expanding the second definition to explicitly include the spatial dimension, this article explores aspects of the therapeutic spaces created by nanomedicine that shift the traditional dimensions of symptom, sign and pathology. This article analyzes three aspects of the therapeutic window in nanomedicine - temporal, spatial and manner of construction and their impact on the dimensions of modern medicine.

  7. Experimental Polyurethane Foam (PUF) Roofing Systems. III. Naval Station, Roosevelt Roads, Puerto Rico, and Naval Facility, Cape Hatteras, North Carolina.

    Science.gov (United States)

    1986-01-01

    other sources of energy loss must be investigated. The units had jalousie windows that permitted a moderate degree of air infiltration and resultant...units with jalousie windows, optimum energy conservation is obtained with 1-1/2 to 3 inches of foam. Naval Facility, Cape Hatteras, N.C. 1. A 25- to...replacing jalousie windows with a closed window. Two to 3 inches of foam should be used to provide maximum energy conservation in semitropical

  8. Status of the SXFEL Facility

    Directory of Open Access Journals (Sweden)

    Zhentang Zhao

    2017-06-01

    Full Text Available The Shanghai soft X-ray Free-Electron Laser facility (SXFEL is being developed in two steps; the SXFEL test facility (SXFEL-TF, and the SXFEL user facility (SXFEL-UF. The SXFEL-TF is a critical development step towards the construction a soft X-ray FEL user facility in China, and is under commissioning at the Shanghai Synchrotron Radiation Facility (SSRF campus. The test facility is going to generate 8.8 nm FEL radiation using an 840 MeV electron linac passing through the two-stage cascaded HGHG-HGHG or EEHG-HGHG (high-gain harmonic generation, echo-enabled harmonic generation scheme. The construction of the SXFEL-TF started at the end of 2014. Its accelerator tunnel and klystron gallery were ready for equipment installation in April 2016, and the installation of the SXFEL-TF linac and radiator undulators were completed by the end of 2016. In the meantime, the SXFEL-UF, with a designated wavelength in the water window region, began construction in November 2016. This was based on upgrading the linac energy to 1.5 GeV, and the building of a second undulator line and five experimental end-stations. Construction status and the future plans of the SXFEL are reported in this paper.

  9. Holographic window for solar power generation

    Science.gov (United States)

    Kasezawa, Toshihiro; Horimai, Hideyoshi; Tabuchi, Hiroshi; Shimura, Tsutomu

    2016-12-01

    A new photovoltaic generation unit based on the application of holographic technologies called a Holo-Window is proposed in this work. The basic principle and the optical configuration used for the basic experimental unit are described. Suitable fabrication technology for a hologram with the broadband spectrum required to provide the appropriate sunlight capture capability is then discussed. Finally, a laboratory-prototype Holo-Window unit was developed and its performance was evaluated.

  10. 桌面型Windows Server 2008

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Windows Server2008是服务器系统,作为桌面使用没有winxp和win7等用起来得心应手,此文通过对该系统一些配置稍作修改,在不影响其服务器系统的性能情况下打造一款更得心应手的桌面型的windows Server 2008。

  11. Windows in Low Energy Houses. Size Matters

    Energy Technology Data Exchange (ETDEWEB)

    Persson, Mari-Louise

    2004-06-01

    A generally accepted way of building passive houses has been to have small windows facing north and a large glass facade to the south. This is to minimize losses on the north side while gaining as much solar heat as possible on the south. In spring 2001, twenty terraced houses were built outside Goeteborg partly in this way. The indoor temperature is kept at a comfortable level by passive methods, using solar gains and internal gains from household appliances and occupants. Heat losses are very low, since the building envelope is well insulated and since modern coated triple-glazed windows have been installed. The purpose of this work is to investigate how decreasing the window size facing south and increasing the window size facing north in low energy houses will influence the energy consumption and maximum power needed to keep the indoor temperature between 23 and 26 deg C. Different climates and orientations have been investigated and so have the influence of occupancy and window type. A dynamic building simulation tool, DEROB, has been used and the simulations indicate an extremely low energy demand for the houses. The results show that the size of the energy efficient windows does not have a major influence on the heating demand in winter, but is of relevant signification looking at the cooling need in summer. This indicates that instead of the traditional technique of building passive houses it is possible to enlarge the window area facing north and get better lighting conditions. To decrease the energy need for cooling, there is an optimal window size facing south that is smaller than the original size of the investigated buildings.

  12. Holographic window for solar power generation

    Science.gov (United States)

    Kasezawa, Toshihiro; Horimai, Hideyoshi; Tabuchi, Hiroshi; Shimura, Tsutomu

    2016-08-01

    A new photovoltaic generation unit based on the application of holographic technologies called a Holo-Window is proposed in this work. The basic principle and the optical configuration used for the basic experimental unit are described. Suitable fabrication technology for a hologram with the broadband spectrum required to provide the appropriate sunlight capture capability is then discussed. Finally, a laboratory-prototype Holo-Window unit was developed and its performance was evaluated.

  13. The discount window : time for reform?

    OpenAIRE

    Craig S. Hakkio; Gordon H. Sellon

    2000-01-01

    For many years, the Federal Reserve's discount window has played an important role in monetary policy. Discount window borrowing helps individual depository institutions manage their reserve accounts in the presence of unexpected deposit and payments flows. Improved reserve management, in turn, helps stabilize the overnight federal funds market by reducing the volatility of short-term interest rates. Moreover, announced changes in the Federal Reserve's discount rate have often signaled import...

  14. Windows with thermal 30% improved balance; Vinduer med 30% bedre energibalance

    Energy Technology Data Exchange (ETDEWEB)

    Schultz, J. M.

    1998-12-31

    The aim of the project has been to investigate and to develop thermally improved windows based on an evaluation of the energy balance of the window, i.e. the total influence of the window on the energy consumption for space heating. The energy balance is the net heat flow per window area which means that both energy losses and transmittance of solar radiation is considered. The final goal of the project was to improve the energy balance of a window with at least 30%. As reference is chosen a common low energy glazing mounted in a wooden frame construction measuring 1188x1188 mm{sup 2}. The transparent area forms about 68% of the total window area and the total U-value of the window is about 1.4 W/(m{sup 2}K). Several theoretical analyses have been carried out and a prototype construction has been made, that meets the goal of a 30% improvement of the energy balance. The prototype has been tested in the guarded hot box facility at the institute and a total U-value of about 1.2 W/(m{sup 2}K) have been measured, which is a reduction compared with the reference window of 0.2 W/(m{sup 2}K). The improvements have primarily been obtained by replacing parts of the frame construction with polystyrene foam insulation. Other frame solutions have been described based on a combined effect of reducing the frame area and improve the insulating properties of the frame construction. (EG)

  15. Mammography Facilities

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Mammography Facility Database is updated periodically based on information received from the four FDA-approved accreditation bodies: the American College of...

  16. Health Facilities

    Science.gov (United States)

    Health facilities are places that provide health care. They include hospitals, clinics, outpatient care centers, and specialized care centers, such as birthing centers and psychiatric care centers. When you ...

  17. Canyon Facilities

    Data.gov (United States)

    Federal Laboratory Consortium — B Plant, T Plant, U Plant, PUREX, and REDOX (see their links) are the five facilities at Hanford where the original objective was plutonium removal from the uranium...

  18. Window Size Impact in Human Activity Recognition

    Directory of Open Access Journals (Sweden)

    Oresti Banos

    2014-04-01

    Full Text Available Signal segmentation is a crucial stage in the activity recognition process; however, this has been rarely and vaguely characterized so far. Windowing approaches are normally used for segmentation, but no clear consensus exists on which window size should be preferably employed. In fact, most designs normally rely on figures used in previous works, but with no strict studies that support them. Intuitively, decreasing the window size allows for a faster activity detection, as well as reduced resources and energy needs. On the contrary, large data windows are normally considered for the recognition of complex activities. In this work, we present an extensive study to fairly characterize the windowing procedure, to determine its impact within the activity recognition process and to help clarify some of the habitual assumptions made during the recognition system design. To that end, some of the most widely used activity recognition procedures are evaluated for a wide range of window sizes and activities. From the evaluation, the interval 1–2 s proves to provide the best trade-off between recognition speed and accuracy. The study, specifically intended for on-body activity recognition systems, further provides designers with a set of guidelines devised to facilitate the system definition and configuration according to the particular application requirements and target activities.

  19. AN INTRODUCTION TO WINDOWS 2000 AT CERN

    CERN Multimedia

    2001-01-01

    A demonstration of the new supported Windows environment for all the CERN personal computers (PC) will be given which is based on Windows 2000. This presentation will assume little or no familiarity with the PC, or NICE, and will concentrate on the services being offered to the users of PCs at CERN. How NICE 2000 can facilitate the work of all users, eventually becoming the key access point to all activities in the laboratory will be demonstrated. Information: http://winservices.web.cern.ch/winservices/Seminars/Tutorials/ Date Title Language Location Speaker Fri 1/6 10:00 Une introduction à Windows 2000 au CERN F IT Auditorium (31/3-004) Alberto Pace Tue 5/6 10:00 Une introduction à Windows 2000 au CERN F LHC Auditorium (30/7th floor) Frederic Hemmer Tue 5/6 14:00 Une introduction à Windows 2000 au CERN F SL Auditorium (864/1s floor) Michel Bornand Tue 5/6 14:00 An introduction to Windows 2000 at CERN E IT Auditorium (31/3-004) Andreas Wagner ...

  20. 解析windows 2003 AD DS与windws 2008 windows 之区别

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    1.封装文件 windows server 2008操作系统中内置了sysprep,sysprep可以在c:\windows\system32\sysprep下找到。其中只有sysprep.exe这一个文件,而windows server 2003中的sysprep是由3个文件构成:sysprep.exesetupmgr.exe和setupcl.exe,可以在windows server安装光盘suppot目录下找到。

  1. Microsoft Windows 7 Administrator's Reference Upgrading, Deploying, Managing, and Securing Windows 7

    CERN Document Server

    Orchilles, Jorge

    2010-01-01

    Microsoft Windows 7 Administrator's Reference gives you a complete overview of all the important day-to-day duties for which administrators are responsible. From a complete overview of upgrading and implementing to a detailed view of security in Windows 7, this book will keep you on track. Coverage includes: installing and deployment, managing the new Windows 7 environment, overview of the new desktop features, and technical help for troubleshooting and networking (to name a few). Written by current systems administrators with a deep experience in Windows, security, and networked and enterpri

  2. Designing for Windows 8 fundamentals of great design in Windows Store apps

    CERN Document Server

    Schooley, Brent

    2013-01-01

    Designing for Windows 8 is a fast-paced, 150-page primer on the key design concepts you need to create successful Windows 8 apps. This book will help you design a user interface that is both delightful and effective, feels 'right' to your users, and encapsulates a great Windows 8 experience. In this book, you will: Meet the building blocks of solid Windows 8 UI design in a well-designed sample app. Learn how to incorporate key design elements into your apps, such as the app bar, charms and subtle animations from the animation library. Find out how to deliver the core experience that your users

  3. A new family of windows--convolution windows and their applications

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Jieqiu; LIANG; Changhong; CHEN; Yanpu

    2005-01-01

    A new family of windows is constructed by convolutions via a few rectangular windows with same time width and is thus referred to as convolution windows. The expressions of the second-order up to the eighth-order convolution windows in both the time and frequency domains are derived. Their applications in high accuracy harmonic analysis of periodic signals are investigated. Comparisons between the proposed windows and some known windows with the same width shows that, when the synchronous deviation of data sampling is slight, the proposed ones have the least effect of spectral leakage. Therefore, the new windows are well suited for high accuracy harmonic analysis and parameter estimation for periodic signals. The error analysis and computer simulations show that the estimation errors, corresponding to frequency,amplitude and phase of every harmonic component of a signal, are proportional to thepth power of the relative frequency deviation in case of the pth-order convolution window is applied to windowing signal of approximately p cycles. By introducing real time adjustment in sampling interval, the proposed algorithm can adaptively trace signal frequency and lead to less sampling synchronous deviation. The proposed approach has the advantages of easy implementation and high measure precision and can be used in harmonic analysis of quasi-periodic signals whose fundamental frequency drifts slowly with time.

  4. Smart windows on the drawing board

    Energy Technology Data Exchange (ETDEWEB)

    Atkinson, C.

    Progress is continuing int he development of windows that can control transmission and reflection of solar radiation. The electrochromic windows change from transparent to reflective when a small amount of electricity is applied to them. These smart windows will be able to reduce both cooling requirements and electricity use for lighting in buildings. Optical density, or color of electrochromic material depends upon the number of ions and electrons within, which can be regulated by applying current. The amount of electricity required for switching depends on the material used, but is on the order of a few milliamperes per square centimeter at 1-2 volts. Power is only drawn during switching. The window switches from transparent to opaque in 5-50 seconds, and the previous state will be remembered for up to 24 hours if the power supply is cut off. Current research at Lawrence Berkeley Laboratory (LBL), focuses on visual lights switching materials for smaller applications, such as car windows and mirrors where solar glare and bright headlights are major problems. LBL's first prototypes had transmissivity ranges of 20% to 65% of visible light. Their goal is to expand the range to 15% to 70%. Study is also underway at the Solar Energy Research Institute (SERI), in Goldern, Colorado, which has patented a plasma-enhanced chemical vapor deposition process developed there. The main issue regarding electrochromic window performance is durability. However, there are many challenges still to be overcome regarding the performance of electrochromic windows. Environmental stability tests are underway at LBL. Water vapor reactivity and cycle lifetime of the materials are also currently being researched.

  5. Electrochromic Window Demonstration at the Donna Land Port of Entry

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, Luis L. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lee, Eleanor S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Thanachareonkit, Anothai [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-05-01

    The U.S. General Services Administration (GSA) Public Buildings Service (PBS) has jurisdiction, custody or control over 105 land ports of entry throughout the United States, 35 of which are located along the southern border. At these facilities, one of the critical functions of windows is to provide border control personnel with direct visual contact with the surrounding environment. This also can be done through surveillance cameras, but the high value that U.S. Customs and Border Protection (CPB) officers place on direct visual contact can be encapsulated in the following statement by a senior officer regarding this project: “nothing replaces line of sight.” In sunny conditions, however, outdoor visibility can be severely compromised by glare, especially when the orb of the sun is in the field of view. This often leads to the deployment of operable shading devices, such as Venetian blinds. While these devices address the glare, they obstruct the view of the surroundings, negating the visual security benefits of the windows.

  6. Sandia's Z-Backlighter Laser Facility

    Science.gov (United States)

    Rambo, P.; Schwarz, J.; Schollmeier, M.; Geissel, M.; Smith, I.; Kimmel, M.; Speas, C.; Shores, J.; Armstrong, D.; Bellum, J.; Field, E.; Kletecka, D.; Porter, J.

    2016-12-01

    The Z-Backlighter Laser Facility at Sandia National Laboratories was developed to enable high energy density physics experiments in conjunction with the Z Pulsed Power Facility at Sandia National Laboratories, with an emphasis on backlighting. Since the first laser system there became operational in 2001, the facility has continually evolved to add new capability and new missions. The facility currently has several high energy laser systems including the nanosecond/multi-kilojoule Z-Beamlet Laser (ZBL), the sub-picosecond/kilojoule- class Z-Petawatt (ZPW) Laser, and the smaller nanosecond/100 J-class Chaco laser. In addition to these, the backlighting mission requires a regular stream of coated consumable optics such as debris shields and vacuum windows, which led to the development of the Sandia Optics Support Facility to support the unique high damage threshold optical coating needs described.

  7. The rarefaction wave propagation in transparent windows

    Science.gov (United States)

    Glam, B.; Porat, E.; Horovitz, Y.; Yosef-Hai, A.

    2017-01-01

    The radial (lateral) rarefaction wave velocity of polymethyl methacrylate (PMMA) and Lithium Fluoride (LiF) windows were studied by plate impact experiments that were carried out at Soreq NRC up to a pressure of 146 kbar in the PMMA and 334 kbar in the LiF. The windows were glued to Lead targets that were impacted by a copper impactor. The VISAR measurement was done in the window interface with the target. This information was utilized to identify the radial rarefaction arrival time at the center of different diameter windows after the shock event, and served as a measurement to the radial wave velocity in the shocked material. It was found that for both windows, LiF or PMMA, the measured radial wave velocity increases with the pressure. Furthermore, this velocity is significantly higher compared to the expected longitudinal sound velocity at the same pressure, calculated by the Steinberg EOS in the PMMA and by ab initio calculation in the LiF. Here we present the experimental results and a comparison with analytical calculation of the sound velocity using the Steinberg EOS.

  8. Performance Evaluation of DSC Windows for Buildings

    Directory of Open Access Journals (Sweden)

    Jun-Gu Kang

    2013-01-01

    Full Text Available Interest in BIPV systems with dye-sensitized solar cells (DSCs that can replace building windows has increased for zero energy buildings. Although DSCs have lower efficiency in terms of electricity generation than silicon solar cells, they allow light transmission and application of various colors; they also have low production costs, which make them especially suitable for BIPV systems. DSC research is interdisciplinary, involving electrical, chemical, material, and metal engineering. A considerable amount of research has been conducted on increasing the electrical efficiency of DSC and their modules. However, there has not been sufficient research on building applications of DSC systems. The aim of this study is to evaluate the optical performance and thermal performance of DSC windows in buildings. For this study, DSC experimental models with different thicknesses and dye colors were manufactured, and their optical properties, such as transmittance and reflectivity, were measured by a spectrometer. The thermal and optical characteristics of double-glazed windows with DSC were analyzed with a window performance analysis program, WINDOW 6.0.

  9. THERM 5 / WINDOW 5 NFRC simulation manual

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Robin; Kohler, Christian; Arasteh, Dariush; Carmody, John; Huizenga, Charlie; Curcija, Dragan

    2003-06-01

    This document, the ''THERM 5/WINDOW 5 NFRC Simulation Manual', discusses how to use the THERM and WINDOW programs to model products for NFRC certified simulations and assumes that the user is already familiar with those programs. In order to learn how to use these programs, it is necessary to become familiar with the material in both the ''THERM User's Manual'' and the ''WINDOW User's Manual''. In general, this manual references the User's Manuals rather than repeating the information. If there is a conflict between either of the User Manual and this ''THERM 5/''WINDOW 5 NFRC Simulation Manual'', the ''THERM 5/WINDOW 5 NFRC Simulation Manual'' takes precedence. In addition, if this manual is in conflict with any NFRC standards, the standards take precedence. For example, if samples in this manual do not follow the current taping and testing NFRC standards, the standards not the samples in this manual, take precedence.

  10. X-Windows Socket Widget Class

    Science.gov (United States)

    Barry, Matthew R.

    2006-01-01

    The X-Windows Socket Widget Class ("Class" is used here in the object-oriented-programming sense of the word) was devised to simplify the task of implementing network connections for graphical-user-interface (GUI) computer programs. UNIX Transmission Control Protocol/Internet Protocol (TCP/IP) socket programming libraries require many method calls to configure, operate, and destroy sockets. Most X Windows GUI programs use widget sets or toolkits to facilitate management of complex objects. The widget standards facilitate construction of toolkits and application programs. The X-Windows Socket Widget Class encapsulates UNIX TCP/IP socket-management tasks within the framework of an X Windows widget. Using the widget framework, X Windows GUI programs can treat one or more network socket instances in the same manner as that of other graphical widgets, making it easier to program sockets. Wrapping ISP socket programming libraries inside a widget framework enables a programmer to treat a network interface as though it were a GUI.

  11. The Moving Window Technique: A Window into Developmental Changes in Attention during Facial Emotion Recognition

    Science.gov (United States)

    Birmingham, Elina; Meixner, Tamara; Iarocci, Grace; Kanan, Christopher; Smilek, Daniel; Tanaka, James W.

    2013-01-01

    The strategies children employ to selectively attend to different parts of the face may reflect important developmental changes in facial emotion recognition. Using the Moving Window Technique (MWT), children aged 5-12 years and adults ("N" = 129) explored faces with a mouse-controlled window in an emotion recognition task. An…

  12. The Moving Window Technique: A Window into Developmental Changes in Attention during Facial Emotion Recognition

    Science.gov (United States)

    Birmingham, Elina; Meixner, Tamara; Iarocci, Grace; Kanan, Christopher; Smilek, Daniel; Tanaka, James W.

    2013-01-01

    The strategies children employ to selectively attend to different parts of the face may reflect important developmental changes in facial emotion recognition. Using the Moving Window Technique (MWT), children aged 5-12 years and adults ("N" = 129) explored faces with a mouse-controlled window in an emotion recognition task. An…

  13. Improved SNR of MST RADAR Signals by Cosine Hyperbolic Window over Kaiser Window

    Directory of Open Access Journals (Sweden)

    Prof. B. Ramesh Reddy Dr. A. Subbarami Reddy Dr. P. Chandrashekar Reddy

    2012-02-01

    Full Text Available In this paper, the effect of window shape parameter “” in Cosine Hyperbolic Window Function on the SNR values of MST RADAR returns has been investigated. Six sets of multibeam observations of the lower atmosphere made by the Indian Mesosphere-Stratosphere-Troposphere (MST RADAR are used for the result analysis. Prior to the Fourier Transformation, the in-phase and quadrature components of the RADAR echo samples are weighted with the recently proposed new class of adjustable window based on the Cosine Hyperbolic Window Function. The effects of data weighting with the variation of the window shape parameter “” of the Cosine Hyperbolic Window Function is presented. It is observed that the increase of “” increases the SNR values and a good improvement is reported. Optimum value of the shape parameter “” for the Cosine Hyperbolic Window Function is suggested to analyze the MST RADAR signals. The results also shows that, the improvement of SNR of noisy data due to the effect of side lobe reduction and demands for the design of optimal windows.

  14. Aviation Engine Test Facilities (AETF) fire protection study

    Science.gov (United States)

    Beller, R. C.; Burns, R. E.; Leonard, J. T.

    1989-07-01

    An analysis is presented to the effectiveness of various types of fire fighting agents in extinguishing the kinds of fires anticipated in Aviation Engine Test Facilities (AETF), otherwise known as Hush Houses. The agents considered include Aqueous Film-Forming Foam, Halon 1301, Halon 1211 and water. Previous test work has shown the rapidity with which aircraft, especially high performance aircraft, can be damaged by fire. Based on this, tentative criteria for this evaluation included a maximum time of 20 s from fire detection to extinguishment and a period of 30 min in which the agent would prevent reignition. Other issues examined included: toxicity, corrosivity, ease of personnel egress, system reliability, and cost effectiveness. The agents were evaluated for their performance in several fire scenarios, including: under frame fire, major engine fire, engine disintegration fire, high-volume pool fire with simultaneous spill fire, internal electrical fire, and runaway engine fire.

  15. Design and fabrication of a window for the gas Cherenkov detector 3

    Science.gov (United States)

    Fatherley, V. E.; Bingham, D. A.; Cartelli, M. D.; DiDomizio, R. A.; Griego, J. R.; Herrmann, H. W.; Lopez, F. E.; Oertel, J. A.; Pollack, M. J.

    2016-11-01

    The gas Cherenkov detector 3 was designed at Los Alamos National Laboratory for use in inertial confinement fusion experiments at both the Omega Laser Facility and the National Ignition Facility. This instrument uses a low-Z gamma-to-electron convertor plate and high pressure gas to convert MeV gammas into UV/visible Cherenkov photons for fast optical detection. This is a follow-on diagnostic from previous versions, with two notable differences: the pressure of the gas is four times higher, and it allows the use of fluorinated gas, requiring metal seals. These changes force significant changes in the window component, having a unique set of requirements and footprint limitations. The selected solution for this component, a sapphire window brazed into a stainless steel flange housing, is described.

  16. Design and fabrication of a window for the gas Cherenkov detector 3

    Energy Technology Data Exchange (ETDEWEB)

    Fatherley, V. E., E-mail: vef@lanl.gov; Bingham, D. A.; Cartelli, M. D.; Griego, J. R.; Herrmann, H. W.; Lopez, F. E.; Oertel, J. A. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); DiDomizio, R. A.; Pollack, M. J. [EnvirOptics, Inc., Colmar, Pennsylvania 18915 (United States)

    2016-11-15

    The gas Cherenkov detector 3 was designed at Los Alamos National Laboratory for use in inertial confinement fusion experiments at both the Omega Laser Facility and the National Ignition Facility. This instrument uses a low-Z gamma-to-electron convertor plate and high pressure gas to convert MeV gammas into UV/visible Cherenkov photons for fast optical detection. This is a follow-on diagnostic from previous versions, with two notable differences: the pressure of the gas is four times higher, and it allows the use of fluorinated gas, requiring metal seals. These changes force significant changes in the window component, having a unique set of requirements and footprint limitations. The selected solution for this component, a sapphire window brazed into a stainless steel flange housing, is described.

  17. Design and fabrication of a window for the gas Cherenkov detector 3.

    Science.gov (United States)

    Fatherley, V E; Bingham, D A; Cartelli, M D; DiDomizio, R A; Griego, J R; Herrmann, H W; Lopez, F E; Oertel, J A; Pollack, M J

    2016-11-01

    The gas Cherenkov detector 3 was designed at Los Alamos National Laboratory for use in inertial confinement fusion experiments at both the Omega Laser Facility and the National Ignition Facility. This instrument uses a low-Z gamma-to-electron convertor plate and high pressure gas to convert MeV gammas into UV/visible Cherenkov photons for fast optical detection. This is a follow-on diagnostic from previous versions, with two notable differences: the pressure of the gas is four times higher, and it allows the use of fluorinated gas, requiring metal seals. These changes force significant changes in the window component, having a unique set of requirements and footprint limitations. The selected solution for this component, a sapphire window brazed into a stainless steel flange housing, is described.

  18. Integral window hermetic fiber optic components

    Energy Technology Data Exchange (ETDEWEB)

    Dalton, R.D.; Kramer, D.P.; Massey, R.T.; Waker, D.A.

    1994-12-31

    In the fabrication of igniters, actuators, detonators, and other pyrotechnic devices to be activated by a laser beam, an integral optical glass window is formed by placing a preform in the structural member of the device and then melting the glass and sealing it in place by heating at a temperature between the ceramming temperature of the glass and the melting point of the metal, followed by rapid furnace cooling to avoid devitrification. No other sealing material is needed to achieve hermeticity. A preferred embodiment of this type of device is fabricated by allowing the molten glass to flow further and form a plano-convex lens integral with and at the bottom of the window. The lens functions to decrease the beam divergence caused by refraction of the laser light passing through the window when the device is fired by means of a laser beam.

  19. Teach yourself visually Windows 8.1

    CERN Document Server

    McFedries, Paul

    2013-01-01

    A practical guide for visual learners eager to get started with Windows 8.1 If you learn more quickly when you can see how things are done, this Visual guide is the easiest way to get up and running on Windows 8.1. It covers more than 150 essential Windows tasks, using full-color screen shots and step-by-step instructions to show you just what to do. Learn your way around the interface and how to install programs, set up user accounts, play music and other media files, download photos from your digital camera, go online, set up and secure an e-mail account, and much more.The tried-and-true f

  20. Radcalc for Windows. Volume 2: Technical manual

    Energy Technology Data Exchange (ETDEWEB)

    Green, J.R.

    1995-09-27

    Radcalc for Windows is a user-friendly menu-driven Windows-compatible software program with applications in the transportation of radioactive materials. It calculates the radiolytic generation of hydrogen gas in the matrix of low-level and high-level radioactive waste using NRC-accepted methodology. It computes the quantity of a radionuclide and its associated products for a given period of time. In addition, the code categorizes shipment quantities as radioactive, Type A or Type B, limited quantity, low specific activity, highway route controlled, and fissile excepted using DOT definitions and methodologies, as outlined in 49 CFR Subchapter C. The code has undergone extensive testing and validation. Volume I is a User`s Guide, and Volume II is the Technical Manual for Radcalc for Windows

  1. Fused silica windows for solar receiver applications

    Science.gov (United States)

    Hertel, Johannes; Uhlig, Ralf; Söhn, Matthias; Schenk, Christian; Helsch, Gundula; Bornhöft, Hansjörg

    2016-05-01

    A comprehensive study of optical and mechanical properties of quartz glass (fused silica) with regard to application in high temperature solar receivers is presented. The dependence of rupture strength on different surface conditions as well as high temperature is analyzed, focussing particularly on damage by devitrification and sandblasting. The influence of typical types of contamination in combination with thermal cycling on the optical properties of fused silica is determined. Cleaning methods are compared regarding effectiveness on contamination-induced degradation for samples with and without antireflective coating. The FEM-aided design of different types of receiver windows and their support structure is presented. A large-scale production process has been developed for producing fused silica dome shaped windows (pressurized window) up to a diameter of 816 mm. Prototypes were successfully pressure-tested in a test bench and certified according to the European Pressure Vessel Directive.

  2. Low-E windows: lighting considerations

    Energy Technology Data Exchange (ETDEWEB)

    Salares, V.; Russell, P. [Canada Mortgage and Housing Corp., Ottawa, ON (Canada). Technical Research Div.

    1996-08-01

    New and retrofitted houses with low-E windows were surveyed to determine owner satisfaction with the product and to collect impressions and observations about occupants` health, plant growth, and lighting and low-E windows. Results indicated that senior citizens were more affected by inadequate lighting because of reduced transmission by the aging lens of the eye to transmit short wavelength light, i. e. the very same ones that are effectively filtered out by low-E coatings. Especially vulnerable were those with environmental hypersensitivity, and those who suffer from seasonal affective disorder (SAD). Plant growth was found to be improved, possibly due to the filtered light provided by low-E windows. On the other hand, lower levels of daylighting means that higher levels of supplemental lighting would be needed, which may, in turn, negate the energy saving from the low-E glazing. 10 refs.

  3. Current Conveyor Based Window Comparator Circuits

    Directory of Open Access Journals (Sweden)

    Sudhanshu Maheshwari

    2016-01-01

    Full Text Available This paper introduces a new window comparator circuit utilizing a new current conveyor and two diodes, operable at ±1.25 V and capable of accurately detecting the voltage windows. Another modified circuit with distinct binary levels suited for automatic control applications is also suggested. Exhaustive simulation results showing detection of windows, as small as 50 mV and as high as 1 V, are included. Comparisons are further drawn with the traditional operational amplifier based circuit and the new circuit is found to benefit from the use of current-mode active element, namely, Extra-X Current Controlled Current Conveyor. The proposed theory is well supported through simulation results.

  4. Combined Pressure and Thermal Window System for Space Vehicles

    Science.gov (United States)

    Svartstrom, Kirk Nils (Inventor)

    2017-01-01

    A window system for a vehicle comprising a pressure and thermal window pane, a seal system, and a retainer system. The pressure and thermal window pane may be configured to provide desired pressure protection and desired thermal protection when exposed to an environment around the vehicle during operation of the vehicle. The pressure and thermal window pane may have a desired ductility. The seal system may be configured to contact the pressure and thermal window pane to seal the pressure and thermal window pane. The retainer system may be configured to hold the seal system and the pressure and thermal window pane.

  5. Energy performance of windows based on the net energy gain

    DEFF Research Database (Denmark)

    Svendsen, Svend; Kragh, Jesper; Laustsen, Jacob Birck

    2005-01-01

    orientation or averaged over different orientations. The averaged value may be used for energy labeling of windows of standard size. Requirements in building codes may also be based on the net energy gain instead of the thermal transmittance of the window. The size and the configuration of the window, i...... of the frame. The two geometry numbers are the area of the glazing unit relative to the window area and the length of the frame profiles relative to the window area. Requirements and classes for the energy performance of the window can be given by assigning values to the two energy performance parameters....... In this way the requirements and classes for the energy performance of the window become a function of the geometry of the window. Therefore the effect of the dimension and the configuration of the actual window are taken into account and make it possible to express the energy performance of all windows...

  6. PV window - Development and demonstrations. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Haugaard, P.

    2011-05-15

    Using the results from the EU project RenewTransnet, which focused on the development of a pane with integrated solar cells, the goal of this project is to develop these principles into a window solution. This window solution is targeted to Danish building tradition and architecture. It is expected that an elegant PV-window solution for both new and retrofit buildings is developed during this project, and which appearance can be customized to each building. Based on results from a related projects carried out by Gaia Solar, the window solution will have the potential of being approximately 30% cheaper than similar products on the market. In this project this price reduction is the objective of the development of a window solution. The project team has succeeded in developing a 2-layer PV-window with glass / glass lamination with EVA as foil, which is 35% cheaper than similar products on the market. Since the price for the frame-profile does not differ significantly at market level, the price comparison is made on the basis of the developed PV-pane. The objective of 30 % price reduction in relation to similar products on the market is met. A special production process to the making glass/glass lamination with EVA as foil has been developed, in which a frame is put around the module which intends both to remove the unwanted tension along the edges, and to prevent the significant spillage of EVA from the module under pressure and prevent the invasive bubbles along the edge of module. Since the developed production method for making glass/glass modules with EVA is simple, a further cost reduction will primarily be in a reduction of the price of the cell. The project process has resulted in the development of a product, which due to continuous restrictions in the building regulations, will be very attractive in future buildings. (LN)

  7. Asian Facilities

    Science.gov (United States)

    Nakahata, M.

    2011-04-01

    Asian underground facilities are reviewed. The YangYang underground Laboratory in Korea and the Kamioka observatory in Japan are operational and several astrophysical experiments are running. Indian Neutrino Observatory(INO) and China JinPing Underground Laboratory (CJPL) are under construction and underground experiments are being prepared. Current activities and future prospects at those underground sites are described.

  8. Characterisation of advanced windows. Determination of thermal properties by measurements

    Energy Technology Data Exchange (ETDEWEB)

    Duer, K.

    2001-04-01

    This report describes work carried out with the aim of facilitating a full energy performance characterisation of advanced windows and glazings by means of measurements. The energy performance of windows and glazings are characterised by two parameters: The thermal transmittance (U-value) and the total solar energy transmittance (g-value) and methods to determine these two parameters by measurements have been investigated. This process has included the improvement of existing equipment and existing measuring methods as well as the development of new measuring equipment and new methods of measuring and data treatment. Measurements of the thermal transmittance of windows and glazings in a guarded hot box have been investigated. The calibration and measuring procedures for determining the U-values of facade windows were analysed and a suggestion for a new calibration and measuring procedure for determining the U-values of roof windows in a guarded hot box was elaborated. The accuracy of the guarded hot box measurements was examined by comparisons to measurements in a hot-plate device and excellent agreement between the results was obtained. Analysis showed that the expected uncertainty in the U-value measurement is about 5% for a specimen with a U-value of 1.75 W/m{sup 2}K. The U-values of three different windows were measured in two separate round robin tests applying two different calibration procedures. The windows U-values where ranging from 1.1 to 2.5 W/m{sup 2}K and all measured results were within the expected uncertainties of the measurements. On the basis of the investigations on hot box measurements a high degree of confidence in the measurement accuracy and the measuring procedure of the guarded hot box at the Department of Buildings and Energy has been obtained. Indoor g-value measurements in a calorimetric test facility (the METSET) mounted in a solar simulator have been investigated and a number of problems regarding these measurements have been

  9. Parallel Performance of MPI Sorting Algorithms on Dual-Core Processor Windows-Based Systems

    CERN Document Server

    Elnashar, Alaa Ismail

    2011-01-01

    Message Passing Interface (MPI) is widely used to implement parallel programs. Although Windowsbased architectures provide the facilities of parallel execution and multi-threading, little attention has been focused on using MPI on these platforms. In this paper we use the dual core Window-based platform to study the effect of parallel processes number and also the number of cores on the performance of three MPI parallel implementations for some sorting algorithms.

  10. Windows Phonen ja HTML5:n sovelluskehitys

    OpenAIRE

    Timonen, Olli

    2013-01-01

    Tässä opinnäytetyössä kehitettiin Ampparit Oy:lle Ampparit.com-mobiilisovellus Windows Phone -alustalle. Mobiilisovelluksen haluttiin näyttävän jo olemassa oleva Ampparit.com HTML5-sivusto ja saada se toimimaan hyvin yhteen alustan kanssa. Ampparit Oy oli jo tuonut Android-sovelluksen saataville ja nyt oli Windows Phonen vuoro. Sovellukset luotiin noudattamalla yksinkertaista ohjelmistotuotantotapaa, jossa käytiin läpi neljä vaihetta: suunnittelu, toteutus, testaus ja julkaisu. Sovellukse...

  11. Impact of coated windows on visual perception

    DEFF Research Database (Denmark)

    Johnsen, Kjeld; Dubois, Marie-Claude

    There is at present an architectural trend promoting the use of large glass facades in commercial and office buildings. These facades generate a large cooling and heating demand creating the need for combined solar-protective and low-emissitivity coated windows. This report describes the results...... of brightness and colours in a space. Overall, the study shows that coated glazings may moderately affect the perception details, slightly affect the perception of glare from window and do not affect the perception of shadows on and around objects in the room. The results also suggest that the perception...

  12. Thin Cryogenic X-ray Windows

    CERN Document Server

    Niinikoski, T O; Davenport, M; Elias, N; Aune, S; Franz, J

    2009-01-01

    We describe the construction and tests of cryogenic X-ray windows of 47 mm diameter made of 15 ìm thick polypropylene foil glued on a UHV flange and supported with a strongback mesh machined by electro-erosion. These hermetic windows of the solar axion telescope of the CAST experiment at CERN withstand the static and dynamic pressures of the buffer gas that are normally below 130 mbar, but may reach 1.2 bar when the magnet quenches. They were tested at 60 K up to 3.5 bar static pressure without permanent deformation.

  13. Windows NT操作系统

    Institute of Scientific and Technical Information of China (English)

    张海杰; 赵凤英; 吴丽丽

    2016-01-01

    Microsoft Windows NT(New Technology)操作系统源于著名的,由Microsoft开发的第一代IBM个人计算机操作系统PC-DOS,Microsoft在1993年从数字设备公司(Digital Equipment Corporation)雇用了一批人员来开发.在基于OS/2 NT基础上编制推出的面向工作站、网络服务器和大型计算机网络的操作系统,这个新系统就是第一代的Windows NT.

  14. Windows Server® 2008 Inside Out

    CERN Document Server

    Stanek, William R

    2009-01-01

    Learn how to conquer Windows Server 2008-from the inside out! Designed for system administrators, this definitive resource features hundreds of timesaving solutions, expert insights, troubleshooting tips, and workarounds for administering Windows Server 2008-all in concise, fast-answer format. You will learn how to perform upgrades and migrations, automate deployments, implement security features, manage software updates and patches, administer users and accounts, manage Active Directory® directory services, and more. With INSIDE OUT, you'll discover the best and fastest ways to perform core a

  15. Mastering Microsoft Windows Small Business Server 2008

    CERN Document Server

    Johnson, Steven

    2010-01-01

    A complete, winning approach to the number one small business solution. Do you have 75 or fewer users or devices on your small-business network? Find out how to integrate everything you need for your mini-enterprise with Microsoft's new Windows Server 2008 Small Business Server, a custom collection of server and management technologies designed to help small operations run smoothly without a giant IT department. This comprehensive guide shows you how to master all SBS components as well as handle integration with other Microsoft technologies.: Focuses on Windows Server 2008 Small Business Serv

  16. Egress of budded virions of Autographa californica nucleopolyhedrovirus does not require activity of Spodoptera frugiperda HSP/HSC70 chaperones.

    Science.gov (United States)

    Lyupina, Yulia V; Orlova, Olga V; Abaturova, Svetlana B; Beljelarskaya, Svetlana N; Lavrov, Andrey N; Mikhailov, Victor S

    2014-11-04

    The induction of heat shock proteins in baculovirus infected cells is well documented. However a role of these chaperones in infection cycle remains unknown. The observation that HSP70s are associated with virions of different baculoviruses reported by several researchers suggests that HSPs might be structural components of viruses or involved in virion assembly. These hypotheses were examined by using a novel inhibitor of the ATPase and chaperoning activity of HSP/HSC70s, VER-155008. When VER-155008 was added early in infection, the synthesis of viral proteins, genome replication and the production of budded virions (BV) were markedly inhibited indicating the dependence of virus reproduction on host chaperones. However, BV production was unaffected when VER-155008 was added in the mid-replication phase which is after accumulation of products required for completion of the viral DNA replication. These results suggest that the final stages in assembly of BV and their egress from cells do not depend on chaperone activity of host HSP/HSC70s.

  17. Pilot Field Test: The Ability to Ambulate After Landing as Assessed with Seat Egress, Walk, and Obstacle Test

    Science.gov (United States)

    Fisher, E. A.; Fomina, E. V.; Reschke, M. F.; Cerisano, J. M.; Kofman, I. S.; Gadd, N. E.; Phillips, T. R.; Lee, S. M. C.; Laurie, S. S.; Stenger, M. B.; Bloomberg, J. J.; Mulavara, A. P.; Kozlovskaya, I. B.; Tomilovskaya, E. S.

    2016-01-01

    Astronauts experience alterations in multiple physiological systems due to exposure to the microgravity conditions of space flight. These changes lead to disruption in the ability to ambulate and perform functional tasks during the initial reintroduction to a gravitational environment. Figure 1 shows a schematic representation of the components involved in postflight ataxia. Full functional recovery has not been sufficiently investigated for long-duration crewmembers. The joint U.S./Russian Pilot Field Test (PFT) experiment (a pre-cursor to Field Test (FT)) was developed to address this gap in knowledge. The PFT was conducted on crewmembers traveling on Soyuz expeditions 34S - 41S and was comprised of several tasks designed to study the recovery of sensorimotor abilities of crewmembers during the first 24 hours after landing and for several days thereafter. Closing this gap will allow us to characterize the ability of crewmembers to perform critical mission tasks that they will be expected to perform after an unassisted landing following 6 to 12 months in microgravity. The Seat Egress, Walk and Obstacle (SEWO) Test will be discussed in this poster.

  18. The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain

    Science.gov (United States)

    Nagel, Claus-Henning; Binz, Anne; Sodeik, Beate; Bauerfeind, Rudolf; Bailer, Susanne M.

    2015-01-01

    Progeny capsids of herpesviruses leave the nucleus by budding through the nuclear envelope. Two viral proteins, the membrane protein pUL34 and the nucleo-phosphoprotein pUL31 form the nuclear egress complex that is required for capsid egress out of the nucleus. All pUL31 orthologs are composed of a diverse N-terminal domain with 1 to 3 basic patches and a conserved C-terminal domain. To decipher the functions of the N-terminal domain, we have generated several Herpes simplex virus mutants and show here that the N-terminal domain of pUL31 is essential with basic patches being critical for viral propagation. pUL31 and pUL34 entered the nucleus independently of each other via separate routes and the N-terminal domain of pUL31 was required to prevent their premature interaction in the cytoplasm. Unexpectedly, a classical bipartite nuclear localization signal embedded in this domain was not required for nuclear import of pUL31. In the nucleus, pUL31 associated with the nuclear envelope and newly formed capsids. Viral mutants lacking the N-terminal domain or with its basic patches neutralized still associated with nucleocapsids but were unable to translocate them to the nuclear envelope. Replacing the authentic basic patches with a novel artificial one resulted in HSV1(17+)Lox-UL31-hbpmp1mp2, that was viable but delayed in nuclear egress and compromised in viral production. Thus, while the C-terminal domain of pUL31 is sufficient for the interaction with nucleocapsids, the N-terminal domain was essential for capsid translocation to sites of nuclear egress and a coordinated interaction with pUL34. Our data indicate an orchestrated sequence of events with pUL31 binding to nucleocapsids and escorting them to the inner nuclear envelope. We propose a common mechanism for herpesviral nuclear egress: pUL31 is required for intranuclear translocation of nucleocapsids and subsequent interaction with pUL34 thereby coupling capsid maturation with primary envelopment. PMID:26083367

  19. The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain.

    Directory of Open Access Journals (Sweden)

    Christina Funk

    2015-06-01

    Full Text Available Progeny capsids of herpesviruses leave the nucleus by budding through the nuclear envelope. Two viral proteins, the membrane protein pUL34 and the nucleo-phosphoprotein pUL31 form the nuclear egress complex that is required for capsid egress out of the nucleus. All pUL31 orthologs are composed of a diverse N-terminal domain with 1 to 3 basic patches and a conserved C-terminal domain. To decipher the functions of the N-terminal domain, we have generated several Herpes simplex virus mutants and show here that the N-terminal domain of pUL31 is essential with basic patches being critical for viral propagation. pUL31 and pUL34 entered the nucleus independently of each other via separate routes and the N-terminal domain of pUL31 was required to prevent their premature interaction in the cytoplasm. Unexpectedly, a classical bipartite nuclear localization signal embedded in this domain was not required for nuclear import of pUL31. In the nucleus, pUL31 associated with the nuclear envelope and newly formed capsids. Viral mutants lacking the N-terminal domain or with its basic patches neutralized still associated with nucleocapsids but were unable to translocate them to the nuclear envelope. Replacing the authentic basic patches with a novel artificial one resulted in HSV1(17+Lox-UL31-hbpmp1mp2, that was viable but delayed in nuclear egress and compromised in viral production. Thus, while the C-terminal domain of pUL31 is sufficient for the interaction with nucleocapsids, the N-terminal domain was essential for capsid translocation to sites of nuclear egress and a coordinated interaction with pUL34. Our data indicate an orchestrated sequence of events with pUL31 binding to nucleocapsids and escorting them to the inner nuclear envelope. We propose a common mechanism for herpesviral nuclear egress: pUL31 is required for intranuclear translocation of nucleocapsids and subsequent interaction with pUL34 thereby coupling capsid maturation with primary

  20. Process window control using CDU master

    Science.gov (United States)

    Fujiwara, Tomoharu; Toki, Tsuyoshi; Tanaka, Daishi; Sato, Maki; Kosugi, Junichi; Tanaka, Rika; Sakasai, Naruo; Ohashi, Toshio; Nakasone, Ryoko; Tokui, Akira

    2012-03-01

    As double patterning techniques such as spacer double/quadruple patterning mature, ArF water immersion lithography is expected to be applied down to the 1x nm hp node or beyond. This will necessitate precise process control solutions to accommodate extremely small process windows. In the case of spacer double/quadruple patterning in particular, CD uniformity of the final feature is strongly related to the lithography performance of the initial pre-spacer feature. CD uniformity of the resist image is affected by many sources. In the case of the exposure tool, CD error on the reticle, as well as exposure dose and focus errors are the key factors. For the resist process, heterogeneity of the stacked resist film thickness, post exposure bake (PEB) plate temperature, and development all have an impact. Furthermore, the process wafer also has error sources that include under-layer non-uniformities or wafer flatness. Fortunately, the majorities of these non-uniformities are quite stable in a volume production process. To improve and maintain the CD uniformity, a technique to calculate exposure dose and focus correction values simultaneously using the measured resist image feature was reported previously [1]. Further, a demonstration of a correction loop using a neural network calculation model was reported in SPIE 2010 [2], and the corrected CD uniformity was less than 1.5 nm (3 sigma) within a wafer. For further improvement, a demonstration of precise dose and focus control using high order field-by-field correction was then reported at SPIE 2011[3]. In that work, the interand intra-field CD uniformities reported were less than 1 nm (3 sigma) respectively. A key aspect of this method is the simultaneous compensation of dose and focus offsets, which successfully maximizes the process margin of a target pattern. The Nikon CDU Master then derives the optimal control parameters for each compensation function in the scanner using the exposure dose and focus correction data

  1. PCS: a pallet costing system for wood pallet manufacturers (version 1.0 for Windows®)

    Science.gov (United States)

    A. Jefferson, Jr. Palmer; Cynthia D. West; Bruce G. Hansen; Marshall S. White; Hal L. Mitchell

    2002-01-01

    The Pallet Costing System (PCS) is a computer-based, Microsoft Windows® application that computes the total and per-unit cost of manufacturing an order of wood pallets. Information about the manufacturing facility, along with the pallet-order requirements provided by the customer, is used in determining production cost. The major cost factors addressed by PCS...

  2. LAFD: TA-16 HE Facility Familiarization Tour, OJT 55258

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Victor Stephen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-31

    Los Alamos National Laboratory (LANL) will conduct familiarization tours for personnel of the Los Alamos County Fire Department (LAFD) at TA-16 high explosives (HE) facilities. These familiarization tours are official LANL business; the purpose of these tours is to orient LAFD firefighters to the facility so that they can respond efficiently and quickly to a variety of emergency situations. This orientation includes, among other topics, ingress and egress of the area and buildings, layout and organization of the facility, evacuation procedures and assembly points, and areas of concern within the various buildings at the facility. LAFD firefighters have the skills and abilities to perform firefighting operations and other emergency response tasks that cannot be provided by LANL personnel who have the required clearance. This handout provides details of the information, along with maps and diagrams, to be presented during the familiarization tours. The handout will be distributed to the trainees at the time of the tour. A corresponding checklist will also be used as guidance during the familiarization tours to ensure that all required information is presented to LAFD personnel.

  3. Windows XP ends its life at CERN – register for Windows 7 training!

    CERN Multimedia

    Michał Kwiatek (IT-OIS)

    2012-01-01

    Windows XP has been around for over 10 years and it is now time to move on. At CERN, general support for Windows XP will end in December 2012, and before this date users are requested to schedule a migration to the next version of WindowsWindows 7.   Windows 7 is already well established at CERN – it is used by a large majority of users. In fact, there was a considerable user demand even before its official release in October 2009 and its adoption has been smooth. Users praise Windows 7 for its improved stability and a clear advantage on laptops is a much more efficient implementation of offline files. The migration to Windows 7 involves a reinstallation of the operating system. Files stored in user home folders on DFS will be immediately available after the reinstallation. Applications will be upgraded to more recent versions and in certain cases, an application may even be replaced by another application providing the same functionality. Microsoft Office suite is a good ...

  4. Broken windows, mediocre methods, and substandard statistics

    NARCIS (Netherlands)

    Wicherts, J.M.; Bakker, M.

    2014-01-01

    Broken windows theory states that cues of inappropriate behavior like litter or graffiti amplify norm-violating behavior. In a series of quasi-experiments, Keizer, Lindenberg, and Steg altered cues of inappropriate behavior in public places and observed how many passersby subsequently violated

  5. Tongue as the Window to the Heart

    Institute of Scientific and Technical Information of China (English)

    Tsung O.Cheng

    2011-01-01

    @@ To the Editor: I read with great interest your masterful article on study of the tongue in patients with coronary heart disease. Tongue is, indeed, the window to the heart. Many cardiovascular diseases including coronary heart disease can be accurately diagnosed by the Chinese traditional physicians by careful inspection of the tongue (Figure 1).

  6. Tongue as the Window to the Heart

    Institute of Scientific and Technical Information of China (English)

    Tsung O. Cheng

    2011-01-01

    To the Editor: I read with great interest your masterful article on study of the tongue in patients with coronary heart disease.Tongue is,indeed,the window to the heart.Many cardiovascular diseases including coronary heart disease can be accurately diagnosed by the Chinese traditional physicians by careful inspection of the tongue(Figure 1).

  7. A methodology to enlarge narrow stability windows

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Ewerton M.P.; Pastor, Jorge A.S.C.; Fontoura, Sergio A.B. [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil). Dept. de Engenharia Civil. Grupo de Tecnologia e Engenharia de Petroleo

    2004-07-01

    The stability window in a wellbore design is defined by the difference between fracture pressure and collapse pressure. Deep water environments typically present narrow stability windows, because rocks have low strength due to under-compaction process. Often also, horizontal wells are drilled to obtain a better development of reservoirs placed in thin layers of sandstone. In this scenario, several challenges are faced when drilling in deep water. The traditional approach for predicting instabilities is to determine collapses and fractures at borehole wall. However, the initiation of rupture does not indicate that the borehole fails to perform its function as a wellbore. Thus, a methodology in which the stability window may be enlarged is desirable. This paper presents one practical analytical methodology that consists in allowing wellbore pressures smaller than the conventional collapse pressure, i.e., based upon failure on the borehole wall. This means that a collapse region (shear failure) will be developed around the borehole wall. This collapse region is pre-defined and to estimate its size is used a failure criterion. The aforementioned methodology is implemented in a user-friendly software, which can perform analyses of stress, pore pressure, formation failure, mud weight and mud salinity design for drilling in shale formations. Simulations of a wellbore drilling in a narrow stability window environment are performed to demonstrate the improvements of using the methodology. (author)

  8. Implementing Audio-CASI on Windows' Platforms.

    Science.gov (United States)

    Cooley, Philip C; Turner, Charles F

    1998-01-01

    Audio computer-assisted self interviewing (Audio-CASI) technologies have recently been shown to provide important and sometimes dramatic improvements in the quality of survey measurements. This is particularly true for measurements requiring respondents to divulge highly sensitive information such as their sexual, drug use, or other sensitive behaviors. However, DOS-based Audio-CASI systems that were designed and adopted in the early 1990s have important limitations. Most salient is the poor control they provide for manipulating the video presentation of survey questions. This article reports our experiences adapting Audio-CASI to Microsoft Windows 3.1 and Windows 95 platforms. Overall, our Windows-based system provided the desired control over video presentation and afforded other advantages including compatibility with a much wider array of audio devices than our DOS-based Audio-CASI technologies. These advantages came at the cost of increased system requirements --including the need for both more RAM and larger hard disks. While these costs will be an issue for organizations converting large inventories of PCS to Windows Audio-CASI today, this will not be a serious constraint for organizations and individuals with small inventories of machines to upgrade or those purchasing new machines today.

  9. The Window of locational opportunity-concept

    NARCIS (Netherlands)

    Boschma, Ron

    1996-01-01

    This article aims to set out a theoretical concept, i.e. the Window of Locational Opportunity concept, which accounts for notions like indeterminacy, human agency and historical accidents when explaining the spatial pattern of newly emerging industries. We will state that their spatial formation doe

  10. Windows Server 2012初体验

    Institute of Scientific and Technical Information of China (English)

    毕晓日; 王洪波

    2013-01-01

    Windows Server 2012虽然已经发布,但它到底会给我们的工作带来哪些便利呢,哪些又是它的亮点呢,本文从我们最常用的应用入手让您可以体验它的新功能!

  11. Time characteristics of PROFIBUS on Windows XP

    NARCIS (Netherlands)

    Huang, Yang

    2005-01-01

    This project is aiming to investigate the use of the PROFIBUS as a fieldbus for control purposes, and to determine the time characteristics of PROFIBUS data transmission between two PCs. The actual experiments are performed with PC¿s running Windows XP, which is a non-realtime OS. The experiments ar

  12. Broken windows, mediocre methods, and substandard statistics

    NARCIS (Netherlands)

    Wicherts, J.M.; Bakker, M.

    2014-01-01

    Broken windows theory states that cues of inappropriate behavior like litter or graffiti amplify norm-violating behavior. In a series of quasi-experiments, Keizer, Lindenberg, and Steg altered cues of inappropriate behavior in public places and observed how many passersby subsequently violated norms

  13. Windowed active sampling for reliable neural learning

    NARCIS (Netherlands)

    Barakova, E.I; Spaanenburg, L

    1998-01-01

    The composition of the example set has a major impact on the quality of neural learning. The popular approach is focused on extensive pre-processing to bridge the representation gap between process measurement and neural presentation. In contrast, windowed active sampling attempts to solve these pro

  14. Edit Distance to Monotonicity in Sliding Windows

    DEFF Research Database (Denmark)

    Chan, Ho-Leung; Lam, Tak-Wah; Lee, Lap Kei

    2011-01-01

    of a data stream is becoming well-understood over the past few years. Motivated by applications on network quality monitoring, we extend the study to estimating the edit distance to monotonicity of a sliding window covering the w most recent items in the stream for any w ≥ 1. We give a deterministic...

  15. New Window into the Human Body

    Science.gov (United States)

    1985-01-01

    Michael Vannier, MD, a former NASA engineer, recognized the similarity between NASA's computerized image processing technology and nuclear magnetic resonance. With technical assistance from Kennedy Space Center, he developed a computer program for Mallinckrodt Institute of Radiology enabling Nuclear Magnetic Resonance (NMR) to scan body tissue for earlier diagnoses. Dr. Vannier feels that "satellite imaging" has opened a new window into the human body.

  16. An acoustic window for sustainable buildings

    Science.gov (United States)

    Kang, Jian; Brocklesby, Martin; Li, Zhemin; Oldham, David J.

    2005-04-01

    Encouraging the use of natural ventilation is an important tendency in the green building movement, but opening windows can often cause noise problems. This research develops a window system which allows natural ventilation while reducing noise transmission. The core idea is to create a ventilation path by staggering two layers of glass and using micro-perforated absorbers (MPA) along the path created to reduce noise. The MPA are made from transparent materials so that daylighting is relatively unaffected. Starting with a brief introduction of the MPA theory and its application in ducts, the paper presents a series of numerical simulations using finite element method based software FEMLAB, and experiment results measured between a semi-anechoic chamber and a reverberation chamber. Performance in acoustics, ventilation and daylighting are all taken into account. A basic window configuration is first considered, studying the effectiveness of various window parameters. A number of strategic designs are then examined, including external hoods and louvers in the sound path. There is generally a good agreement between simulation and measurement, and the noise reduction can be as good as a single glazing, with air movement to achieve occupant comfort, rather than just for minimum air exchange. [Work supported by EPSRC.

  17. Performance of the Analog Moving Window Detector

    DEFF Research Database (Denmark)

    Hansen, V. Gregers

    1970-01-01

    A type of analog integrating moving window detector for use with a scanning pulse radar is examined. A performance analysis is carried out, which takes into account both the radiation pattern of the antenna and the dynamic character of the detection process due to the angular scanning...

  18. Windows Phone 8 application development essentials

    CERN Document Server

    Szostak, Tomasz

    2013-01-01

    A mini-tutorial full of code examples and strategies to give you plenty of options when building your own applications for Windows Phone 8.This book is ideal if you are a developers who wants to get into mobile development. Some C# background may be useful for a complete understanding.

  19. Windows 8: What Educators Need to Know

    Science.gov (United States)

    Vedder, Richard G.

    2012-01-01

    In October 2012, Microsoft will release the commercial version of its next operating system, presently called "Windows 8." This version represents a significant departure from the past. Microsoft wants this operating system to meet user needs regardless of physical platform (e.g., desktop, notebook, tablet, mobile phone). As part of this mission,…

  20. Probabilistic modeling durability of wooden window frames

    NARCIS (Netherlands)

    Straalen, IJ.J. van; Abspoel-Bukman, L.M.; Courage, W.M.G.; Mennink, J.

    2014-01-01

    Nowadays, maintenance of wooden window frames strongly depends on the practical experience of the parties involved. To get a better understanding of the required maintenance period and maintenance actions, a model has been developed to predict durability. This model makes it possible to optimize mai

  1. The Zwicky Transient Facility Camera

    Science.gov (United States)

    Dekany, Richard; Smith, Roger M.; Belicki, Justin; Delacroix, Alexandre; Duggan, Gina; Feeney, Michael; Hale, David; Kaye, Stephen; Milburn, Jennifer; Murphy, Patrick; Porter, Michael; Reiley, Daniel J.; Riddle, Reed L.; Rodriguez, Hector; Bellm, Eric C.

    2016-08-01

    The Zwicky Transient Facility Camera (ZTFC) is a key element of the ZTF Observing System, the integrated system of optoelectromechanical instrumentation tasked to acquire the wide-field, high-cadence time-domain astronomical data at the heart of the Zwicky Transient Facility. The ZTFC consists of a compact cryostat with large vacuum window protecting a mosaic of 16 large, wafer-scale science CCDs and 4 smaller guide/focus CCDs, a sophisticated vacuum interface board which carries data as electrical signals out of the cryostat, an electromechanical window frame for securing externally inserted optical filter selections, and associated cryo-thermal/vacuum system support elements. The ZTFC provides an instantaneous 47 deg2 field of view, limited by primary mirror vignetting in its Schmidt telescope prime focus configuration. We report here on the design and performance of the ZTF CCD camera cryostat and report results from extensive Joule-Thompson cryocooler tests that may be of broad interest to the instrumentation community.

  2. Windows registry forensics advanced digital forensic analysis of the Windows registry

    CERN Document Server

    Carvey, Harlan

    2011-01-01

    Harlan Carvey brings readers an advanced book on Windows Registry - the most difficult part of Windows to analyze in forensics! Windows Registry Forensics provides the background of the Registry to help develop an understanding of the binary structure of Registry hive files. Approaches to live response and analysis are included, and tools and techniques for postmortem analysis are discussed at length. Tools and techniques will be presented that take the analyst beyond the current use of viewers and into real analysis of data contained in the Registry. This book also has a DVD containing tools, instructions and videos.

  3. Windows 7 Tweaks A Comprehensive Guide on Customizing, Increasing Performance, and Securing Microsoft Windows 7

    CERN Document Server

    Sinchak, Steve

    2009-01-01

    The definitive guide to unlocking the hidden potential of the Windows 7 OS. Written by bestselling author and the creator of tweaks.com Steve Sinchak, this unique guide provides you with the ultimate collection of hidden gems that will enable you to get the most out of Windows 7. Packed with more than 400 pages of insider tips, the book delves beneath the surface to reveal little-known ways to tweak, modify, and customize Windows 7 so you can get every ounce of performance from your operating system. Regardless of your experience with tweaking your system, you'll find fascinating and fun tips

  4. Windows 8 XAML primer your essential guide to Windows 8 development

    CERN Document Server

    Liberty, Jesse

    2012-01-01

    Windows 8 XAML Primer is a fast-paced introduction to XAML for Windows 8 developers who are already proficient C# coders. It introduces you specifically to the world of XAML development for Windows 8 apps in a practical, hands-on way - so you'll be building apps from the very first pages. Building on your existing C# knowledge, you're introduced to XAML from the ground up - what it is, what it does, and why it's important in Windows 8 development. You'll quickly learn how to use XAML efficiently within Visual Studio. You'll find practical coding quickstarts to get your XAML hands-on knowledge

  5. Window Energy Rating System and Calculation of Energy Performance of Windows

    DEFF Research Database (Denmark)

    Laustsen, Jacob Birck; Svendsen, Svend

    , and for reference condi-tions it is used for classification of panes. In actual situations the net energy gain is dependent on window orientation, climate and shadows. Therefore a simple calculation program is made that takes these circumstances into account. The program is combined with a database of Danish......The goal of reducing the energy consumption in buildings is the background for the introduction of an energy rating system of fenestration products in Denmark. The energy rating system requires that producers declare, among other things, the heat loss coefficient, U, and the total solar energy...... transmittance, g, for the panes and whole windows. The energy balance of a window can be described by the net energy gain, which is the solar gain minus the heat loss during the heating season. The net energy gain is a suitable quantity for evaluating the energy performance of windows in a simple and direct way...

  6. Windows 7 A quick, hands-on introduction

    CERN Document Server

    Lee, Wei-Meng

    2009-01-01

    This compact book offers the quickest path for Windows users to get started with Microsoft's Windows 7 operating system. You get the essential information you need to upgrade or install the system and configure it to fit your activities, along with a tour of Windows 7's features and built-in applications. Microsoft has learned from the mistakes of Windows Vista, and Windows 7 shows it-this new OS is much faster and more stable. With Windows 7: Up and Running, you'll learn what's new and what's changed from XP and Vista, and get advice on ways to use this system for work, entertainment, inst

  7. Windows Server 2003活动目录

    Institute of Scientific and Technical Information of China (English)

    魏静

    2006-01-01

    活动目录是Windows 2000 Server在Windows NT Server4.0的基础上,进一步发展起来的。基于对Windows 2000底层的扩展,Windows Server 2003增强了活动目录的功能,下面给大家具体介绍一下在活动目录方面。Windows 2003比Windows 2000有哪些改进及新的特性。

  8. Emission Facilities - Erosion & Sediment Control Facilities

    Data.gov (United States)

    NSGIC Education | GIS Inventory — An Erosion and Sediment Control Facility is a DEP primary facility type related to the Water Pollution Control program. The following sub-facility types related to...

  9. Gabor windows supported on [ − 1, 1] and dual windows with small support

    DEFF Research Database (Denmark)

    Christensen, Ole; Kim, Hong Oh; Kim, Rae Young

    2012-01-01

    Consider a continuous function g ∈ L 2(ℝ) that is supported on [ − 1, 1] and generates a Gabor frame with translation parameter 1 and modulation parameter 0 for some N ∈ ℕ. Under an extra condition on the zeroset of the window g we show that there exists a continuous dual window supported on [ − N...

  10. A novel vacuum window for megawatt gyrotrons

    Science.gov (United States)

    Haldeman, George Stephenson

    2001-08-01

    This thesis describes a new microwave output window for megawatt power level, 110 GHz gyrotrons. The window uses two spherically polished sapphire elements separated by a nearly uniform gap of about 1 mm. Pressurized, microwave transparent coolant flows through this gap and across the transmitting aperture, removing absorbed energy at the element face. The design differs from previous face- cooled windows because the sapphire elements have a modestly curved dome, rather than flat shape. This curved shape increases the element's capability to withstand coolant pressures without significantly increasing stresses from differential heating. Consequently, window power can be increased either through enhanced, high pressure cooling or by using thinner elements with reduced microwave absorption. A model was developed to predict window power capability as a function of design geometry. This model predicted an increase from 0.5 to 2.1 MW when flat elements were changed to curved. Both designs used full size, 100mm clear apertures, but the curved elements with 214 mm curvature radii were 1.3 rather than 1.75 mm thick. The model was also used to design a half size prototype experiment. This 50 mm clear aperture system used 60 mm OD x 0.47 mm thick x 107 mm surface radius elements. An initial piece was fabricated and statically tested to a pressure of 1.1 MPa well above the 0.5 MPa analytically predicted to be required for megawatt operation. The complete window structure was then fabricated, including instrumentation to simulate microwave heating and to measure induced temperatures and strains. Test results demonstrated an equivalent continuous Gaussian beam power capability of 700 kW using a coolant flow of 1.1 lps. Scaling from this measurement, fall size boiling limited power is expected to be 1.1 MW for a Gaussian microwave intensity profile, or 2.3 MW for a shaped profile typical of previous flat, face-cooled designs. (Copies available exclusively from MIT Libraries, Rm

  11. APLIKASI GAME QUIZ ANIMALS BERBASIS WINDOWS 8

    Directory of Open Access Journals (Sweden)

    Yulyani Arifin

    2013-11-01

    Full Text Available Game is currently in great demand by various circles, especially children. Children's interest in the game can be used as a tool to increase childrens intellectuality, i.e. English competence. The purpose of this study is to design an animal-themed quiz game in English language based on Windows 8 operating system, followed by making a game prototype designed. This game is expected to be an exciting educational tool for children in learning English and broadening the knowledge about types of animal. The research is conducted through the stages of game design requirements, game design, evaluation and implementation. Based on the results of the evaluation it is found that thoroughly the game already meets the standards of IMK by Shneiderman and Plaisant (2010. It is good enough as a game-play since it is available at Window Store.

  12. Windows10的版本

    Institute of Scientific and Technical Information of China (English)

    王春海

    2015-01-01

    版本概览Windows 10有7个版本,版本类型分别是:家庭版(Home)、专业版(Professional)、企业版(Enterprise)、教育版(Education)、移动版(Mobile)、移动企业版(MobileEnterprise)以及物联网核心版(10TCore)。微软同时公布了Windows7/8.1(WP8.1)用户可以免费升级的版本类型:家庭版、专业版和移动版。

  13. 初尝WindowsPhone7

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    随着首款行货WindowsPhone7手机的发布,标志着微软手机系统正式回到了国内手机市场。实际上WindowsPhone7并不是今天才发布的,经历了7、7.5两个版本后才正式进入中国。在这一轮以i0S和闩几droid引发的移动狂潮之前,几乎都是山indowsmobile的天下,曾几何时HTCS1等手机占据着智能手机市场的绝大部分市场。

  14. Material Developing for ADS Beam Window

    Institute of Scientific and Technical Information of China (English)

    XUYong-li; XUYuan-chao; LIHua-qing; NINGGuang-sheng; WANFa-rong; ZHAOFei

    2003-01-01

    The irradiation damage and the chemical interaction with the coolant for the ADS target and the structure materials are the key issues in ADS engineering. The developing of the materials that are irradiation and corrosion resistance is the important topic in ADS program in many countries. In this case,a topic of the material developing for the beam window has been proposed in our ADS program.

  15. Thin-ice Arctic Acoustic Window (THAAW)

    Science.gov (United States)

    2014-09-30

    STATEMENT A. Approved for public release; distribution is unlimited. Thin- ice Arctic Acoustic Window (THAAW) Peter F. Worcester Scripps Institution of...of the ice cover and extensive warming of the intermediate layers. The multiyear ice is melting . Ice keels are getting smaller. With more open water...determine the fundamental limits to signal processing in the Arctic imposed by ocean and ice processes. The hope is that these first few new steps will

  16. Energy Loss of Proton in Extraction Window

    Institute of Scientific and Technical Information of China (English)

    LIU; Bao-jie; ZENG; Zi-qiang

    2015-01-01

    The particle is transported in vacuum in accelerator,and is exported through extraction windows.The Kapton foil is used in a 3 MeV proton accelerator.The energy loss of 3 MeV proton is calculated when it comes through Kapton foil of different thicknesses with Monte Carlo method.The energy loss of 3 MeV proton in

  17. Windows® 7 Administrator's Pocket Consultant

    CERN Document Server

    Stanek, William

    2009-01-01

    Portable and precise, this pocket-sized guide delivers immediate answers for the day-to-day administration of Windows 7-from desktop configuration and management to networking and security issues. Zero in on core support and maintenance tasks by using quick-reference tables, instructions, and lists. You'll get the precise information you need to solve problems and get the job done-whether at your desk or in the field!

  18. Doing smooth pursuit paradigms in Windows 7

    DEFF Research Database (Denmark)

    Wilms, Inge Linda

    Smooth pursuit eye movements are interesting to study as they reflect the subject’s ability to predict movement of external targets, keep focus and move the eyes appropriately. The process of smooth pursuit requires collaboration between several systems in the brain and the resulting action may p...... in Windows 7 with live capturing of eye movements using a Tobii TX300 eye tracker. In particular, the poster describes the challenges and limitations created by the hardware and the software...

  19. Diamondlike carbon protective coatings for optical windows

    Science.gov (United States)

    Swec, Diane M.; Mirtich, Michael J.

    1989-01-01

    Diamondlike carbon (DLC) films were deposited on infrared transmitting optical windows and were evaluated as protective coatings for these windows exposed to particle and rain erosion. The DLC films were deposited on zinc selenide (ZnSe) and zinc sulfide (ZnS) by three different ion beam methods: (1) sputter deposition from a carbon target using an 8-cm argon ion source; (2) direct deposition by a 30-cm hollow cathode ion source with hydrocarbon gas in argon; and (3) dual beam direct deposition by the 30-cm hollow cathode ion source and an 8-cm argon ion source. In an attempt to improve the adherence of the DLC films on ZnSc and ZnS, ion beam cleaning, ion implantation with helium and neon ions, or sputter deposition of a thin, ion beam intermediate coating was employed prior to deposition of the DLC film. The protection that the DLC films afforded the windows from particle and rain erosion was evaluated, along with the hydrogen content, adherence, intrinsic stress, and infrared transmittance of the films. Because of the elevated stress levels in the ion beam sputtered DLC films and in those ion beam deposited with butane, films thicker than 0.1 micron and with good adherence on ZnS and ZnSe could not be generated. An intermediate coating of germanium successfully allowed the DLC films to remain adherent to the optical windows and caused only negligible reduction in the specular transmittance of the ZnS and ZnSe at 10 microns.

  20. Windows Server 2012 vulnerabilities and security

    Directory of Open Access Journals (Sweden)

    Gabriel R. López

    2015-09-01

    Full Text Available This investigation analyses the history of the vulnerabilities of the base system Windows Server 2012 highlighting the most critic vulnerabilities given every 4 months since its creation until the current date of the research. It was organized by the type of vulnerabilities based on the classification of the NIST. Next, given the official vulnerabilities of the system, the authors show how a critical vulnerability is treated by Microsoft in order to countermeasure the security flaw. Then, the authors present the recommended security approaches for Windows Server 2012, which focus on the baseline software given by Microsoft, update, patch and change management, hardening practices and the application of Active Directory Rights Management Services (AD RMS. AD RMS is considered as an important feature since it is able to protect the system even though it is compromised using access lists at a document level. Finally, the investigation of the state of the art related to the security of Windows Server 2012 shows an analysis of solutions given by third parties vendors, which offer security products to secure the base system objective of this study. The recommended solution given by the authors present the security vendor Symantec with its successful features and also characteristics that the authors considered that may have to be improved in future versions of the security solution.

  1. A review of electrochromic window performance factors

    Energy Technology Data Exchange (ETDEWEB)

    Selkowitz, S.E.; Rubin, M.; Lee, E.S.; Sullivan, R.; Finlayson, E.; Hopkins, D.

    1994-04-01

    The performance factors which will influence the market acceptance of electrochromic windows are reviewed. A set of data representing the optical properties of existing and foreseeable electrochromic window devices was generated. The issue of reflective versus absorbing electrochromics was explored. This data was used in the DOE 2.1 building energy model to calculate the expected energy savings compared to conventional glazings. The effects of several different control strategies were tested. Significant energy and peak electric demand benefits were obtained for some electrochromic types. Use of predictive control algorithms to optimize cooling control may result in greater energy savings. Initial economic results considering annual savings, cooling equipment cost savings, and electrochromic window costs are presented. Calculations of thermal and visual comfort show additional benefits from electrochromics but more work is needed to quantify their importance. The design freedom and aesthetic possibilities of these dynamic glazings should provide additional market benefits, but their impact is difficult to assess at this time. Ultimately, a full assessment of the market viability of electrochromics must consider the impacts of all of these issues.

  2. Optimum Energy Window In Liver Scintigraphy

    Directory of Open Access Journals (Sweden)

    Alireza Sadremomtaz

    2015-07-01

    Full Text Available Abstract In liver scintigraphy radioactive tracers in addition to liver are accumulated in other organs such as spleen. It leads to the presence of secondary source which affects image quality. Therefore knowing the influence of the noise arising from the secondary source and trying to reduce the additional data is necessary. In nuclear medicine imaging using of energy window is a useful way to reduce the noise. In this paper we try to find an optimum energy window to reduce the noise for two different low energy collimators. Liver scintigraphy images with and without activity in spleen were simulated by SIMIND software with different energy window percentages and with Low-Energy High-Resolution LEHR and Low-Energy General-Purpose LEGP collimators. We used with activity of 190 MBq. Spleen was outside of the camera field of view so that just its noise effects on the liver image is examined. Finally the images of liver with activity in spleen were compared with that without activity in spleen by MATLAB code.

  3. Evaluation criteria and test methods for electrochromic windows

    Energy Technology Data Exchange (ETDEWEB)

    Czanderna, A.W. (Solar Energy Research Inst., Golden, CO (USA)); Lampert, C.M. (Lawrence Berkeley Lab., CA (USA))

    1990-07-01

    Report summarizes the test methods used for evaluating electrochromic (EC) windows, and summarizes what is known about degradation of their performance, and recommends methods and procedures for advancing EC windows for buildings applications. 77 refs., 13 figs., 6 tabs.

  4. A microwave window for K band electromagnetic systems

    DEFF Research Database (Denmark)

    Rybalko, Oleksandr

    2017-01-01

    This article proposes a solution for microwave window at K band. Properties of the window such as performance (transparency) at microwave frequencies, dimensions, and mounting place are discussed. The dimensions of the window were optimized in a full-wave simulator. To verify the design and simul......This article proposes a solution for microwave window at K band. Properties of the window such as performance (transparency) at microwave frequencies, dimensions, and mounting place are discussed. The dimensions of the window were optimized in a full-wave simulator. To verify the design...... and simulation results the prototype of the window is realized by implementing into transition section and tested experimentally. The microwave window provides low return loss |S11| below −30 dB, low insertion loss |S21| below −0.5 dB and can be used for electromagnetic systems where vacuum sealing is required...

  5. The research of optical windows used in aircraft sensor systems

    Institute of Scientific and Technical Information of China (English)

    Zhou Feng; Li Yan; Tang Tian-Jin

    2012-01-01

    The optical windows used in aircrafts protect their imaging sensors from environmental effects.Considering the imaging performance,flat surfaces are traditionally used in the design of optical windows.For aircrafts operating at high speeds,the optical windows should be relatively aerodynamic,but a flat optical window may introduce unacceptably high drag to the airframes.The linear scanning infrared sensors used in aircrafts with,respectively,a fiat window,a spherical window and a toric window in front of the aircraft sensors are designed and compared.Simulation results show that the optical design using a toric surface has the integrated advantages of field of regard,aerodynamic drag,narcissus effect,and imaging performance,so the optical window with a toric surface is demonstrated to be suited for this application.

  6. Improving Wang-Landau sampling with adaptive windows.

    Science.gov (United States)

    Cunha-Netto, A G; Caparica, A A; Tsai, Shan-Ho; Dickman, Ronald; Landau, D P

    2008-11-01

    Wang-Landau sampling (WLS) of large systems requires dividing the energy range into "windows" and joining the results of simulations in each window. The resulting density of states (and associated thermodynamic functions) is shown to suffer from boundary effects in simulations of lattice polymers and the five-state Potts model. Here, we implement WLS using adaptive windows. Instead of defining fixed energy windows (or windows in the energy-magnetization plane for the Potts model), the boundary positions depend on the set of energy values on which the histogram is flat at a given stage of the simulation. Shifting the windows each time the modification factor f is reduced, we eliminate border effects that arise in simulations using fixed windows. Adaptive windows extend significantly the range of system sizes that may be studied reliably using WLS.

  7. An Intelligent Window for Optimal Ventilation and Minimum Thermal Loss

    DEFF Research Database (Denmark)

    Mortensen, Lone Hedegaard; Rose, Jørgen; Liu, Mingzhe;

    This report compares the simulation results of 12 window typologies for four countries on four selected days. The simulation results are used to select the window frame construction including glazing type and pane configuration....

  8. Air Quality Facilities

    Data.gov (United States)

    Iowa State University GIS Support and Research FacilityFacilities with operating permits for Title V of the Federal Clean Air Act, as well as facilities required to submit an air emissions inventory, and other facilities...

  9. Theme: Laboratory Facilities Improvement.

    Science.gov (United States)

    Miller, Glen M.; And Others

    1993-01-01

    Includes "Laboratory Facilities Improvement" (Miller); "Remodeling Laboratories for Agriscience Instruction" (Newman, Johnson); "Planning for Change" (Mulcahy); "Laboratory Facilities Improvement for Technology Transfer" (Harper); "Facilities for Agriscience Instruction" (Agnew et al.); "Laboratory Facility Improvement" (Boren, Dwyer); and…

  10. ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.

    Science.gov (United States)

    Han, Ziying; Madara, Jonathan J; Liu, Yuliang; Liu, Wenbo; Ruthel, Gordon; Freedman, Bruce D; Harty, Ronald N

    2015-10-01

    Ebola (EBOV) is an enveloped, negative-sense RNA virus belonging to the family Filoviridae that causes hemorrhagic fever syndromes with high-mortality rates. To date, there are no licensed vaccines or therapeutics to control EBOV infection and prevent transmission. Consequently, the need to better understand the mechanisms that regulate virus transmission is critical to developing countermeasures. The EBOV VP40 matrix protein plays a central role in late stages of virion assembly and egress, and independent expression of VP40 leads to the production of virus-like particles (VLPs) by a mechanism that accurately mimics budding of live virus. VP40 late (L) budding domains mediate efficient virus-cell separation by recruiting host ESCRT and ESCRT-associated proteins to complete the membrane fission process. L-domains consist of core consensus amino acid motifs including PPxY, P(T/S)AP, and YPx(n)L/I, and EBOV VP40 contains overlapping PPxY and PTAP motifs whose interactions with Nedd4 and Tsg101, respectively, have been characterized extensively. Here, we present data demonstrating for the first time that EBOV VP40 possesses a third L-domain YPx(n)L/I consensus motif that interacts with the ESCRT-III protein Alix. We show that the YPx(n)L/I motif mapping to amino acids 18-26 of EBOV VP40 interacts with the Alix Bro1-V fragment, and that siRNA knockdown of endogenous Alix expression inhibits EBOV VP40 VLP egress. Furthermore, overexpression of Alix Bro1-V rescues VLP production of the budding deficient EBOV VP40 double PTAP/PPEY L-domain deletion mutant to wild-type levels. Together, these findings demonstrate that EBOV VP40 recruits host Alix via a YPx(n)L/I motif that can function as an alternative L-domain to promote virus egress.

  11. Window area and development drive spatial variation in bird-window collisions in an urban landscape.

    Directory of Open Access Journals (Sweden)

    Stephen B Hager

    Full Text Available Collisions with windows are an important human-related threat to birds in urban landscapes. However, the proximate drivers of collisions are not well understood, and no study has examined spatial variation in mortality in an urban setting. We hypothesized that the number of fatalities at buildings varies with window area and habitat features that influence avian community structure. In 2010 we documented bird-window collisions (BWCs and characterized avian community structure at 20 buildings in an urban landscape in northwestern Illinois, USA. For each building and season, we conducted 21 daily surveys for carcasses and nine point count surveys to estimate relative abundance, richness, and diversity. Our sampling design was informed by experimentally estimated carcass persistence times and detection probabilities. We used linear and generalized linear mixed models to evaluate how habitat features influenced community structure and how mortality was affected by window area and factors that correlated with community structure. The most-supported model was consistent for all community indices and included effects of season, development, and distance to vegetated lots. BWCs were related positively to window area and negatively to development. We documented mortalities for 16/72 (22% species (34 total carcasses recorded at buildings, and BWCs were greater for juveniles than adults. Based on the most-supported model of BWCs, the median number of annual predicted fatalities at study buildings was 3 (range = 0-52. These results suggest that patchily distributed environmental resources and levels of window area in buildings create spatial variation in BWCs within and among urban areas. Current mortality estimates place little emphasis on spatial variation, which precludes a fundamental understanding of the issue. To focus conservation efforts, we illustrate how knowledge of the structural and environmental factors that influence bird-window

  12. The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysis.

    OpenAIRE

    Moritz Treeck; Sanders, John L.; Rajshekhar Y Gaji; Kacie A LaFavers; Child, Matthew A.; Gustavo Arrizabalaga; Elias, Joshua E.; John C Boothroyd

    2014-01-01

    Calcium-dependent protein kinases (CDPKs) are conserved in plants and apicomplexan parasites. In Toxoplasma gondii, TgCDPK3 regulates parasite egress from the host cell in the presence of a calcium-ionophore. The targets and the pathways that the kinase controls, however, are not known. To identify pathways regulated by TgCDPK3, we measured relative phosphorylation site usage in wild type and TgCDPK3 mutant and knock-out parasites by quantitative mass-spectrometry using stable isotope-labelin...

  13. A Clamped Be Window for the Dump of the HiRadMat Experiment at CERN

    CERN Document Server

    Delonca, M; Grenier, D; Maglioni, C; Sarrio Martinez, A

    2012-01-01

    At CERN, the High Radiation to Materials facility (HiRadMat) is designed to test accelerator components under the impact of high-intensity pulsed beams and will start operation in 2012. In this frame an LHC TED-type dump was installed at the end of the line, working in nitrogen over-pressure, and a 254μm-thick beryllium window was placed as barrier between the inside of the dump and the external atmosphere. Because of the special loading conditions, a clamped window design was especially developed, optimized and implemented, the more standard welded window not being suitable for such loads. Considering then the clamping force and the applied differential pressures, the stresses on the window components were carefully evaluated thanks to empirical as well as numerical models, to guarantee the structural integrity of the beryllium foil. This paper reports on choices and optimizations that led to the final design, presenting also comparative results from different solutions and the detailed results for the adop...

  14. A Clamped Be Window for the Dump of the HiRadMat Experiment at CERN

    CERN Document Server

    Delonca, M; Grenier, D; Maglioni, C; Sarrio Martinez, A

    2012-01-01

    At CERN, the High Radiation to Materials facility (HiRadMat) is designed to test accelerator components under the impact of high-intensity pulsed beams and will start operation in 2012. In this frame an LHC TED-type dump was installed at the end of the line, working in nitrogen overpressure, and a 254μm-thick beryllium window was placed as barrier between the inside of the dump and the external atmosphere. Because of the special loading conditions, a clamped window design was especially developed, optimized and implemented, the more standard welded window not being suitable for such loads. Considering then the clamping force and the applied differential pressures, the stresses on the window components were carefully evaluated thanks to empirical as well as numerical models, to guarantee the structural integrity of the beryllium foil. This paper reports on choices and optimizations that led to the final design, presenting also comparative results from different solutions and the detailed results for the adopt...

  15. Large-scale fabrication of pseudocapacitive glass windows that combine electrochromism and energy storage.

    Science.gov (United States)

    Yang, Peihua; Sun, Peng; Chai, Zhisheng; Huang, Langhuan; Cai, Xiang; Tan, Shaozao; Song, Jinhui; Mai, Wenjie

    2014-10-27

    Multifunctional glass windows that combine energy storage and electrochromism have been obtained by facile thermal evaporation and electrodeposition methods. For example, WO3 films that had been deposited on fluorine-doped tin oxide (FTO) glass exhibited a high specific capacitance of 639.8 F g(-1). Their color changed from transparent to deep blue with an abrupt decrease in optical transmittance from 91.3% to 15.1% at a wavelength of 633 nm when a voltage of -0.6 V (vs. Ag/AgCl) was applied, demonstrating its excellent energy-storage and electrochromism properties. As a second example, a polyaniline-based pseudocapacitive glass was also developed, and its color can change from green to blue. A large-scale pseudocapacitive WO3-based glass window (15×15 cm(2)) was fabricated as a prototype. Such smart pseudocapacitive glass windows show great potential in functioning as electrochromic windows and concurrently powering electronic devices, such as mobile phones or laptops.

  16. 46 CFR 72.05-30 - Windows and airports.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Windows and airports. 72.05-30 Section 72.05-30 Shipping... Structural Fire Protection § 72.05-30 Windows and airports. (a) For the purpose of this subpart, all glass in windows or airports shall be at least 1/4 inch thick. However, greater thickness may be required...

  17. Iterative algorithms to approximate canonical Gabor windows: Computational aspects

    DEFF Research Database (Denmark)

    Janssen, A.J.E.M; Søndergaard, Peter Lempel

    In this paper we investigate the computational aspects of some recently proposed iterative methods for approximating the canonical tight and canonical dual window of a Gabor frame (g,a,b). The iterations start with the window g while the iteration steps comprise the window g, the k^th iterand...

  18. Iterative algorithms to approximate canonieal Gabor windows: Computational aspects

    DEFF Research Database (Denmark)

    Janssen, A. J. E. M.; Søndergaard, Peter Lempel

    2007-01-01

    In this article we investigate the computational aspects of some recently proposed iterative methods for approximating the canonical tight and canonical dual window of a Gabor frame (g, a, b). The iterations start with the window g while the iteration steps comprise the window g, the k(th) iterand...

  19. Compare of Energy Efficiency of Windows in Aalborg and Chongqing

    DEFF Research Database (Denmark)

    Zhenguo, Lin; Heiselberg, Per; Yao, Runming

    2007-01-01

    Focus on window's energy efficiency, this paper compared the difference of windows in Aalborg and Chongqing. The author analysed the designing process, the thermal insulation performances, the sun shading devices and the ventilation of windows in Aalborg and Chongqing respectively. Furthermore, t...

  20. Impact of three window configurations on daylight conditions

    DEFF Research Database (Denmark)

    Dubois, Marie-Claude; Sørensen, Karl Grau; Traberg-Borup, Steen

    The report describes the results of a pilot study on daylight conditions in simple rooms of residential buildings. As a tool for the analyses the Radiance Lighting Simulating System was used to simulate one room with three different window configurations, a vertical window, a dormer window, and a...

  1. Empirical assessment of a prismatic daylight-redirecting window film in a full-scale office testbed

    Energy Technology Data Exchange (ETDEWEB)

    Thanachareonkit, Anothai; Lee, Eleanor S.; McNeil, Andrew

    2013-08-31

    Daylight redirecting systems with vertical windows have the potential to offset lighting energy use in deep perimeter zones. Microstructured prismatic window films can be manufactured using low-cost, roll-to-roll fabrication methods and adhered to the inside surface of existing windows as a retrofit measure or installed as a replacement insulating glass unit in the clerestory portion of the window wall. A clear film patterned with linear, 50-250 micrometer high, four-sided asymmetrical prisms was fabricated and installed in the south-facing, clerestory low-e, clear glazed windows of a full-scale testbed facility. Views through the film were distorted. The film was evaluated in a sunny climate over a two-year period to gauge daylighting and visual comfort performance. The daylighting aperture was small (window-towall ratio of 0.18) and the lower windows were blocked off to isolate the evaluation to the window film. Workplane illuminance measurements were made in the 4.6 m (15 ft) deep room furnished as a private office. Analysis of discomfort glare was conducted using high dynamic range imaging coupled with the evalglare software tool, which computes the daylight glare probability and other metrics used to evaluate visual discomfort. The window film was found to result in perceptible levels of discomfort glare on clear sunny days from the most conservative view point in the rear of the room looking toward the window. Daylight illuminance levels at the rear of the room were significantly increased above the reference window condition, which was defined as the same glazed clerestory window but with an interior Venetian blind (slat angle set to the cut-off angle), for the equinox to winter solstice period on clear sunny days. For partly cloudy and overcast sky conditions, daylight levels were improved slightly. To reduce glare, the daylighting film was coupled with a diffusing film in an insulating glazing unit. The diffusing film retained the directionality of the

  2. Windows 8回收站取证分析%Recycle Bin Forensic for Windows 8

    Institute of Scientific and Technical Information of China (English)

    宋冰

    2012-01-01

    在计算机取证过程中,对于删除文件的分析常常提供有价值的信息。知道在哪里找到被删除文件并且能够理解文件被删除过程中产生的元数据,这是一个合格的计算机取证人员必备的素质。本文对Window8系统的回收站与传统的WindowsXP系统的回收站的相似点和不同点进行了对比分析,并详细说明了Windows8系统回收站的工作细节,以期为计算机取证人员提供帮助。%Analysis of deleted files often provides useful information for the forensic computer examiner. Knowing where to find the deleted files, and how to interpret the metadata associated with the file's deletion, make up the cornerstone of a successful forensic computer examination. In this paper, the author compares and contrasts the similarities and differences of the Recycle Bin of the Windows 8 between the Recycle Bin of the Windows XP Operating System. In this investigation, the author points-out the details of each implementation that are of interest for the forensic computer examiner.

  3. IMPROVIING THE ABILITY OF FOXPRO WITH WINDOWS API%用WINDOWS API增强FOXPRO功能

    Institute of Scientific and Technical Information of China (English)

    何珍祥

    2002-01-01

    通过在FOXPRO中调用WINDOWS API函数实现计算机软硬件环境测试、进行多媒体处理,介绍在FOXPRO中调用WINDOWS API函数的基本方法,阐述利用WINDOWS API函数增强FOXPRO的重要性.

  4. Windows Server 2012 -palvelimen hallinta PowerShell-komennoilla

    OpenAIRE

    Pitkänen, Henri

    2013-01-01

    Tämän opinnäytetyön tavoitteena oli perehtyä Windows Server 2012 -palvelimen ja aktiivihakemiston hallintaan käyttäen Windows PowerShell -komentotulkkia. PowerShell on Microsoftin kehittämä komentotulkki ja skriptausympäristö, jonka tarkoitus on tehostaa ja automatisoida Windows-käyttöjärjestelmien ja sovellusten hallintaa komentorivin ja skriptien avulla. Opinnäytetyössä käsiteltiin Windows Server 2012 -käyttöjärjestelmään, aktiivihakemistoon ja Windows PowerShell -komentotulkkiin liitty...

  5. Highly Insulating Windows Volume Purchase Program Final Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-04-01

    This report documents the development, execution outcomes and lessons learned of the Highly Insulating Windows Volume Purchase (WVP) Program carried out over a three-year period from 2009 through 2012. The primary goals of the program were met: 1) reduce the incremental cost of highly insulating windows compared to ENERGY STAR windows; and 2) raise the public and potential buyers’ awareness of highly insulating windows and their benefits. A key outcome of the program is that the 2013 ENERGY STAR Most Efficient criteria for primary residential windows were adopted from the technical specifications set forth in the WVP program.

  6. Windows Server 2012 -palvelimen hallinta PowerShell-komennoilla

    OpenAIRE

    2013-01-01

    Tämän opinnäytetyön tavoitteena oli perehtyä Windows Server 2012 -palvelimen ja aktiivihakemiston hallintaan käyttäen Windows PowerShell -komentotulkkia. PowerShell on Microsoftin kehittämä komentotulkki ja skriptausympäristö, jonka tarkoitus on tehostaa ja automatisoida Windows-käyttöjärjestelmien ja sovellusten hallintaa komentorivin ja skriptien avulla. Opinnäytetyössä käsiteltiin Windows Server 2012 -käyttöjärjestelmään, aktiivihakemistoon ja Windows PowerShell -komentotulkkiin liitty...

  7. Measure Guideline. Energy-Efficient Window Performance and Selection

    Energy Technology Data Exchange (ETDEWEB)

    Carmody, John [Univ. of Minnesota, St. Paul, MN (United States). NorthernSTAR; Haglund, Kerry [Univ. of Minnesota, St. Paul, MN (United States). NorthernSTAR

    2012-11-01

    This document provides guidelines for the selection of energy-efficient windows in new and existing residential construction in all U.S. climate zones. It includes information on window products, their attributes and performance. It provides cost/benefit information on window energy savings as well as information on non-energy benefits such as thermal comfort and reduced HVAC demands. The report also provides information on energy impacts of design decisions such as window orientation, total glazing area and shading devices and conditions. Information on resources for proper window installation is included as well.

  8. Exam 70-411 administering Windows Server 2012

    CERN Document Server

    Course, Microsoft Official Academic

    2014-01-01

    Microsoft Windows Server is a multi-purpose server designed to increase reliability and flexibility of  a network infrastructure. Windows Server is the paramount tool used by enterprises in their datacenter and desktop strategy. The most recent versions of Windows Server also provide both server and client virtualization. Its ubiquity in the enterprise results in the need for networking professionals who know how to plan, design, implement, operate, and troubleshoot networks relying on Windows Server. Microsoft Learning is preparing the next round of its Windows Server Certification program

  9. Windows 2000 Cluster Technology Guide%Windows 2000集群技术应用

    Institute of Scientific and Technical Information of China (English)

    姚彤; 陈星

    2001-01-01

    介绍了Windows 2000集群技术的基本概念、工作原理和具体的实施方案,以及在 具体实施中应该注意的一些问题。%On the basis of introduction of the conception, ele ments and implement scenario of Windows 2000 cluster technol ogy, some factors which should be taken into consideration when implement duster technology are addressed in this paper.

  10. Parametric Study Of Window Frame Geometry

    DEFF Research Database (Denmark)

    Zajas, Jan Jakub; Heiselberg, Per

    2013-01-01

    This paper describes a parametric study on window frame geometry with the goal of designing frames with very good thermal properties. Three different parametric frame models are introduced, deseribed by a number of variables. In the first part of the study, a process of sensitivity analysis...... is conducted to determine which of the parameters describing the frame have the highest impact on its thermal performance. Afterwards, an optimization process is conducted on each frame in order to optimize the design with regard to three objectives: minimizing the thermal transmittance, maxim izing the net...

  11. Pro WF Windows Workflow in NET 40

    CERN Document Server

    Bukovics, Bruce

    2010-01-01

    Windows Workflow Foundation (WF) is a revolutionary part of the .NET 4 Framework that allows you to orchestrate human and system interactions as a series of workflows that can be easily mapped, analyzed, adjusted, and implemented. As business problems become more complex, the need for workflow-based solutions has never been more evident. WF provides a simple and consistent way to model and implement complex problems. As a developer, you focus on developing the business logic for individual workflow tasks. The runtime handles the execution of those tasks after they have been composed into a wor

  12. Parametric Study Of Window Frame Geometry

    DEFF Research Database (Denmark)

    Zajas, Jan Jakub; Heiselberg, Per

    2013-01-01

    This paper describes a parametric study on window frame geometry with the goal of designing frames with very good thermal properties. Three different parametric frame models are introduced, deseribed by a number of variables. In the first part of the study, a process of sensitivity analysis is co...... energy gain factor and minimizing the material use. Since the objectives contradiet each other, it was found that it is not possible to identifY a single solution that satisfies all these goals. lnstead, a compromise between the objectives has to be found....

  13. Hacking of Passwords in Windows Environment

    Directory of Open Access Journals (Sweden)

    C.K. GOEL

    2012-06-01

    Full Text Available Hacking is so simple! Not only the operating system‟s loop holes offers opportunities to hackers but also the applications like Skype and Google Chrome developed for the operating systems are quite attractive to hackers. In this paper I present the various ways in which the passwords like user account‟s passwords stored by the operating system or the passwords required by different applications are stored on the system and can be hacked by intended hackers. This paper presents in depth research of the password storage mechanisms implemented in various versions of Windows and various application software and can be exploited by hackers.

  14. Windows Vista for Starters The Missing Manual

    CERN Document Server

    Pogue, David

    2010-01-01

    Fast-paced and easy to use, this concise book teaches you the basics of Windows Vista so you can start using this operating system right away. Written by "New York Times" columnist, bestselling author, Emmy-winning CBS News correspondent and Missing Manuals creator David Pogue, the book will help you: Navigate the desktop, including the fast, powerful and fully integrated desktop search functionUse the Media Center to record TV and radio, present photos, play music, and record all of these to a DVDBreeze across the Web with the vastly improved Internet Explorer 7 tabbed browserBecome familiar

  15. Guidebook to R graphics using Microsoft Windows

    CERN Document Server

    Takezawa, Kunio

    2012-01-01

    Introduces the graphical capabilities of R to readers new to the software Due to its flexibility and availability, R has become the computing software of choice for statistical computing and generating graphics across various fields of research. Guidebook to R Graphics Using Microsoft® Windows offers a unique presentation of R, guiding new users through its many benefits, including the creation of high-quality graphics. Beginning with getting the program up and running, this book takes readers step by step through the process of creating histograms, boxplots, strip charts, time series gra

  16. High-dynamic-range water window ptychography

    CERN Document Server

    Rose, Max; Senkbeil, Tobias; von Gundlach, Andreas R; Stuhr, Susan; Rumancev, Christoph; Besedin, Ilya; Skopintsev, Petr; Viefhaus, Jens; Rosenhahn, Axel; Vartanyants, Ivan A

    2016-01-01

    Ptychographic imaging with soft X-rays, especially in the water window energy range, suffers from limited detector dynamic range that directly influences the maximum spatial resolution achievable. High-dynamic-range data can be obtained by multiple exposures. By this approach we have increased the dynamic range of a ptychographic data set by a factor of 76 and obtained diffraction signal till the corners of the detector. The real space half period resolution was improved from 50 nm for the single exposure data to 18 nm for the high-dynamic-range data.

  17. Window taper functions for subaperture processing.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2013-12-01

    It is well known that the spectrum of a signal can be calculated with a Discrete Fourier Transform (DFT), where best resolution is achieved by processing the entire data set. However, in some situations it is advantageous to use a staged approach, where data is first processed within subapertures, and the results are then combined and further processed to a final result. An artifact of this approach is the creation of grating lobes in the final response. The nature of the grating lobes, including their amplitude and spacing, is an artifact of window taper functions, subaperture offsets, and subaperture processing parameters. We assess these factors and exemplify their effects.

  18. Windows PowerShell深入应用

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Windows PowerShell是微软公司为Windows环境开发的外壳程序及命令行脚本语言技术。这项技术提供了丰富的控制与系统自动化管理功能。发布两年多来,微软的众多产品已经开始支持它,那么目前国内的IT管理员们是否能够习惯它,实际应用情况又如何呢?

  19. Windows 8.1 all-in-one for dummies

    CERN Document Server

    Leonhard, Woody

    2013-01-01

    Ten minibooks in one get you thoroughly caught up on Windows 8.1! With new improvements and changes, Windows 8.1 offers a refreshed user interface, better integration between the new and traditional Windows interfaces, and more. This updated top-selling guide is what you need to get up to speed on everything Windows 8.1. Nine minibooks in one cover such essential topics as navigating the new Start Screen, understanding Windows 8.1 apps, securing Windows 8.1, and much more. Take the guesswork out of Windows 8.1 from day one with this complete, all-in-one resource. Helps you get up to speed on

  20. Improving Wang-Landau sampling with adaptive windows

    Science.gov (United States)

    Cunha-Netto, A. G.; Caparica, A. A.; Tsai, Shan-Ho; Dickman, Ronald; Landau, D. P.

    2008-11-01

    Wang-Landau sampling (WLS) of large systems requires dividing the energy range into “windows” and joining the results of simulations in each window. The resulting density of states (and associated thermodynamic functions) is shown to suffer from boundary effects in simulations of lattice polymers and the five-state Potts model. Here, we implement WLS using adaptive windows. Instead of defining fixed energy windows (or windows in the energy-magnetization plane for the Potts model), the boundary positions depend on the set of energy values on which the histogram is flat at a given stage of the simulation. Shifting the windows each time the modification factor f is reduced, we eliminate border effects that arise in simulations using fixed windows. Adaptive windows extend significantly the range of system sizes that may be studied reliably using WLS.

  1. Window-mounted unit cleans air at hazardous waste site

    Energy Technology Data Exchange (ETDEWEB)

    Battaglia, J.M. (Independent Equipment Corp., Raritan, NJ (United States)); Sawyer, P.

    1994-07-01

    Uncontrolled hazardous waste sites present the potential for exposure to numerous airborne chemicals--both identified and unidentified. This was the case at an Elizabeth, N.J., remediation project managed by a major environmental contractor. The four-acre site housed three active manufacturing facilities and was bordered by an operation commuter railroad line. About 6,300 drums of assorted organic chemicals, mostly acid chlorides and bromides, awaited sampling and removal. In addition, 120 tanks and vessels required sampling, characterization and removal. Due to site restrictions, support trailers were located relatively close to active work areas. Damaged drums littering the site contained water-reactive, organic acid chlorides and bromides, and released slight emissions during humid or rainy conditions. Shifting winds could (and did) carry trace releases or trace contaminants toward the trailers, potentially exposing unprotected workers. Efforts were begun to alleviate even trace contaminant at levels in the remediation site's temporary office trailers. One potential solution to managing trace contaminants at the site was to use a window-mounted, air conditioner-type unit that would replenish each trailer with filtered air three times an hour, and provide positive pressure in the trailer to compensate for repeated openings and closings of doors. The design uses common, off-the-shelf components to temper the approximately 10 percent makeup air, which provides positive pressure.

  2. Analysis of oil-pipeline distribution of multiple products subject to delivery time-windows

    Science.gov (United States)

    Jittamai, Phongchai

    This dissertation defines the operational problems of, and develops solution methodologies for, a distribution of multiple products into oil pipeline subject to delivery time-windows constraints. A multiple-product oil pipeline is a pipeline system composing of pipes, pumps, valves and storage facilities used to transport different types of liquids. Typically, products delivered by pipelines are petroleum of different grades moving either from production facilities to refineries or from refineries to distributors. Time-windows, which are generally used in logistics and scheduling areas, are incorporated in this study. The distribution of multiple products into oil pipeline subject to delivery time-windows is modeled as multicommodity network flow structure and mathematically formulated. The main focus of this dissertation is the investigation of operating issues and problem complexity of single-source pipeline problems and also providing solution methodology to compute input schedule that yields minimum total time violation from due delivery time-windows. The problem is proved to be NP-complete. The heuristic approach, a reversed-flow algorithm, is developed based on pipeline flow reversibility to compute input schedule for the pipeline problem. This algorithm is implemented in no longer than O(T·E) time. This dissertation also extends the study to examine some operating attributes and problem complexity of multiple-source pipelines. The multiple-source pipeline problem is also NP-complete. A heuristic algorithm modified from the one used in single-source pipeline problems is introduced. This algorithm can also be implemented in no longer than O(T·E) time. Computational results are presented for both methodologies on randomly generated problem sets. The computational experience indicates that reversed-flow algorithms provide good solutions in comparison with the optimal solutions. Only 25% of the problems tested were more than 30% greater than optimal values and

  3. STS-32 MS Dunbar trains in JSC Manipulator Development Facility (MDF)

    Science.gov (United States)

    1989-01-01

    STS-32 Mission Specialist (MS) Bonnie J. Dunbar reviews checklist with training personnel in the Manipulator Development Facility (MDF) in JSC's Mockup and Integration Facility (MAIL) Bldg 9A. Dunbar (left) discusses procedures with trainer in front of the aft flight deck onorbit station controls. Overhead window W8 is visible above their heads.

  4. Development of new S-band RF window for stable high-power operation in linear accelerator RF system

    Science.gov (United States)

    Joo, Youngdo; Lee, Byung-Joon; Kim, Seung-Hwan; Kong, Hyung-Sup; Hwang, Woonha; Roh, Sungjoo; Ryu, Jiwan

    2017-09-01

    For stable high-power operation, a new RF window is developed in the S-band linear accelerator (Linac) RF systems of the Pohang Light Source-II (PLS-II) and the Pohang Accelerator Laboratory X-ray Free-Electron Laser (PAL-XFEL). The new RF window is designed to mitigate the strength of the electric field at the ceramic disk and also at the waveguide-cavity coupling structure of the conventional RF window. By replacing the pill-box type cavity in the conventional RF window with an overmoded cavity, the electric field component perpendicular to the ceramic disk that caused most of the multipacting breakdowns in the ceramic disk was reduced by an order of magnitude. The reduced electric field at the ceramic disk eliminated the Ti-N coating process on the ceramic surface in the fabrication procedure of the new RF window, preventing the incomplete coating from spoiling the RF transmission and lowering the fabrication cost. The overmoded cavity was coupled with input and output waveguides through dual side-wall coupling irises to reduce the electric field strength at the waveguide-cavity coupling structure and the possibility of mode competitions in the overmoded cavity. A prototype of the new RF window was fabricated and fully tested with the Klystron peak input power, pulse duration and pulse repetition rate of 75 MW, 4.5 μs and 10 Hz, respectively, at the high-power test stand. The first mass-produced new RF window installed in the PLS-II Linac is running in normal operation mode. No fault is reported to date. Plans are being made to install the new RF window to all S-band accelerator RF modules of the PLS-II and PAL-XFEL Linacs. This new RF window may be applied to the output windows of S-band power sources like Klystron as wells as the waveguide windows of accelerator facilities which operate in S-band.

  5. Infecting Windows, Linux & Mac in one go

    CERN Multimedia

    Computer Security Team

    2012-01-01

    Still love bashing on Windows as you believe it is an insecure operating system? Hold on a second! Just recently, a vulnerability has been published for Java 7.   It affects Windows/Linux PCs and Macs, Internet Explorer, Safari and Firefox. In fact, it affects all computers that have enabled the Java 7 plug-in in their browser (Java 6 and earlier is not affected). Once you visit a malicious website (and there are plenty already out in the wild), your computer is infected… That's "Game Over" for you.      And this is not the first time. For a while now, attackers have not been targeting the operating system itself, but rather aiming at vulnerabilities inherent in e.g. your Acrobat Reader, Adobe Flash or Java programmes. All these are standard plug-ins added into your favourite web browser which make your web-surfing comfortable (or impossible when you un-install them). A single compromised web-site, however, is sufficient to prob...

  6. The GODDESS ionization chamber: developing robust windows

    Science.gov (United States)

    Blanchard, Rose; Baugher, Travis; Cizewski, Jolie; Pain, Steven; Ratkiewicz, Andrew; Goddess Collaboration

    2015-10-01

    Reaction studies of nuclei far from stability require high-efficiency arrays of detectors and the ability to identify beam-like particles, especially when the beam is a cocktail beam. The Gammasphere ORRUBA Dual Detectors for Experimental Structure Studies (GODDESS) is made up of the Oak Ridge-Rutgers University Barrel Array (ORRUBA) of silicon detectors for charged particles inside of the gamma-ray detector array Gammasphere. A high-rate ionization chamber is being developed to identify beam-like particles. Consisting of twenty-one alternating anode and cathode grids, the ionization chamber sits downstream of the target chamber and is used to measure the energy loss of recoiling ions. A critical component of the system is a thin and robust mylar window which serves to separate the gas-filled ionization chamber from the vacuum of the target chamber with minimal energy loss. After construction, windows were tested to assure that they would not break below the required pressure, causing harm to the wire grids. This presentation will summarize the status of the ionization chamber and the results of the first tests with beams. This work is supported in part by the U.S. Department of Energy and National Science Foundation.

  7. Material selection for spallation neutron source windows

    Energy Technology Data Exchange (ETDEWEB)

    Sordo, F. [ETSII/Universidad Politecnica de Madrid, J. Gutierrez Abascal, 2-28006 Madrid (Spain); Abanades, A. [ETSII/Universidad Politecnica de Madrid, J. Gutierrez Abascal, 2-28006 Madrid (Spain)], E-mail: abanades@etsii.upm.es; Lafuente, A.; Martinez-Val, J.M. [ETSII/Universidad Politecnica de Madrid, J. Gutierrez Abascal, 2-28006 Madrid (Spain); Perlado, M. [Instituto de Fusion Nuclear (DENIM)/ETSII/Universidad Politecnica, Madrid, J. Gutierrez Abascal, 2-28006 Madrid (Spain)

    2009-11-15

    High performance neutron sources are being proposed for many scientific and industrial applications, ranging from material studies, hybrid reactors and transmutation of nuclear wastes. In the case of transmutation of nuclear wastes, accelerator driven systems (ADS) are considered as one of the main technical options for such purpose. In ADS a high performance spallation neutron source becomes an essential element for its operation and control. This spallation source must fulfil very challenging nuclear and thermo-mechanical requirements, because of the high neutron rates needed in ADS. The material selection for this key component becomes of paramount importance, particularly the source window that separates the vacuum accelerator tube from the spallation material where the accelerated protons impinge. In this paper, an integral analysis of spallation sources is done, taking as a reference the projects in this field proposal in the framework of European projects. Our analysis and calculations show that titanium and vanadium alloys are more suitable than steel as structural material for an industrial ADS beam window, mostly due to its irradiation damage resistance.

  8. Current status of photoprotection by window glass, automobile glass, window films, and sunglasses.

    Science.gov (United States)

    Almutawa, Fahad; Vandal, Robert; Wang, Steven Q; Lim, Henry W

    2013-04-01

    Ultraviolet radiation (UVR) has known adverse effects on the skin and eyes. Practitioners are becoming more aware of the importance of outdoor photoprotection. However, little attention is directed to the exposure of the skin and eyes to UVR through the window glass or sunglasses. The amount of ultraviolet transmission through glass depends mainly on the type of the glass. All types of commercial and automobile glass block the majority of ultraviolet-B; however, the degree of ultraviolet-A transmission depends on the type of glass. Laminated glass offers better UVA protection than tempered glass; new safety regulations for automobiles may result in increased use of laminated glass for side windows. Window films can be applied to glass to increase UVR protection. Sunglasses need to be compliant with one of the national standards; a wraparound style or side shields offer the best protection. Increased understanding by practitioners on the transmission of UVR through glass, window films, and sunglasses would allow them to better educate the public and to better manage photosensitive patients.

  9. Nuclear Egress of Herpesviruses

    Institute of Scientific and Technical Information of China (English)

    Richard J.Roller

    2008-01-01

    Herpesviruses assemble and fill their capsids in the infected cell nucleus,and must then move this enormous macromolecular assembly across the nuclear membrane and into the cytoplasm.Doing so is a complex,multi-step process that involves envelopment of the capsid at the inner nuclear membrane and de-envelopment by fusion with the outer nuclear membrane.This process is orchestrated by viral proteins,but requires the modification of cellular structures and mechanisms including the nuclear lamina.In this review I summarize recent research on the mechanism of nuclear envelopment and the viral and cellular systems involved in its execution.

  10. Design of the beryllium window for Brookhaven Linac Isotope Producer

    Energy Technology Data Exchange (ETDEWEB)

    Nayak, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Mapes, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Raparia, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-11-01

    In the Brookhaven Linac Isotope Producer (BLIP) beam line, there were two Beryllium (Be) windows with an air gap to separate the high vacuum upstream side from low vacuum downstream side. There had been frequent window failures in the past which affected the machine productivity and increased the radiation dose received by workers due to unplanned maintenance. To improve the window life, design of Be window is reexamined. Detailed structural and thermal simulations are carried out on Be window for different design parameters and loading conditions to come up with better design to improve the window life. The new design removed the air gap and connect the both beam lines with a Be window in-between. The new design has multiple advantages such as 1) reduces the beam energy loss (because of one window with no air gap), 2) reduces air activation due to nuclear radiation and 3) increased the machine reliability as there is no direct pressure load during operation. For quick replacement of this window, an aluminum bellow coupled with load binder was designed. There hasn’t been a single window failure since the new design was implemented in 2012.

  11. North Slope, Alaska ESI: FACILITY (Facility Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains data for oil field facilities for the North Slope of Alaska. Vector points in this data set represent oil field facility locations. This data...

  12. Summary on the preliminary assessment of the T91 window performance in the MEGAPIE conditions

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Y. [Spallation Neutron Source Division, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Fazio, C. [Program Nuclear Safety Research, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany)]. E-mail: concetta.fazio@nuklear.fzk.de; Gorse, D. [CNRS - CECM, 15 Rue G. Urbain, Vitry sur Seine cedex (France); Groeschel, F. [Spallation Neutron Source Division, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Henry, J. [Commissariat a l' Energie Atomique, Saclay, 91191 Gif sur Yvette cedex (France); Terlain, A. [Commissariat a l' Energie Atomique, Saclay, 91191 Gif sur Yvette cedex (France); Vogt, J.-B. [Laboratoire de Metallurgie Physique et Genie des Materiaux, Universite de Lille1, 59655 Villeneuve d' Ascq cedex (France); Auger, T. [CNRS - CECM, 15 Rue G. Urbain, Vitry sur Seine cedex (France); Gessi, A. [Ente per le Nuove Tecnologie l' Energia e l' Ambiente, CR Brasimone, 40032 Camugnano Bologna (Italy)

    2006-06-23

    The MEGAwatt PIlot Experiment (MEGAPIE) target is a liquid lead-bismuth eutectic neutron spallation target, which is considered as a key experiment for the development of accelerator driven systems to transmute high level nuclear waste. The target has been designed in the frame of an international collaboration and it will be installed and irradiated at the SINQ facility of the Paul Scherrer Institut, Switzerland. This paper summarises the experiments done to assess the performance of the MEGAPIE window material, which is made of martensitic steel T91.

  13. Jupiter Laser Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Jupiter Laser Facility is an institutional user facility in the Physical and Life Sciences Directorate at LLNL. The facility is designed to provide a high degree...

  14. Basic Research Firing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Basic Research Firing Facility is an indoor ballistic test facility that has recently transitioned from a customer-based facility to a dedicated basic research...

  15. Performance Evaluation of Vinyl Replacement Windows.

    Science.gov (United States)

    1980-07-15

    Kisatsky, Paul; Barbarisi, Modesto ; Tirellis, Gus, A Preliminary Thermographic Heat Survey of ARRADCOM Facilities - Dover, New Jersey, Army Armament...Conservation: Detailed Tabulations by U. S. Population Segments: Waves 22 and 23, Opinion Research Corporation, Princeton, New Jersey, 1975. Robinson, Henry

  16. Windows 8.1 for seniors for dummies

    CERN Document Server

    Weverka, Peter

    2013-01-01

    Seniors, here's what you need to get up and running on Windows 8.1 Microsoft, now a little older and wiser, is back with Windows 8.1, the revamped version that brings fresh changes and welcome improvements to the Windows 8 operating system. And now you savvy seniors can get the very most out of this easier-to-use Windows 8.1 with our friendly new guide. Using large print that makes the book easier to read plus magnified screen shots to help make Windows less intimidating, this book walks you through common tasks and show you how to get things done in fine style. Helps you get to know Windows

  17. Replicate periodic windows in the parameter space of driven oscillators

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, E.S., E-mail: esm@if.usp.br [Instituto de Fisica, Universidade de Sao Paulo, Sao Paulo (Brazil); Souza, S.L.T. de [Universidade Federal de Sao Joao del-Rei, Campus Alto Paraopeba, Minas Gerais (Brazil); Medrano-T, R.O. [Departamento de Ciencias Exatas e da Terra, Universidade Federal de Sao Paulo, Diadema, Sao Paulo (Brazil); Caldas, I.L. [Instituto de Fisica, Universidade de Sao Paulo, Sao Paulo (Brazil)

    2011-11-15

    Highlights: > We apply a weak harmonic perturbation to control chaos in two driven oscillators. > We find replicate periodic windows in the driven oscillator parameter space. > We find that the periodic window replication is associated with the chaos control. - Abstract: In the bi-dimensional parameter space of driven oscillators, shrimp-shaped periodic windows are immersed in chaotic regions. For two of these oscillators, namely, Duffing and Josephson junction, we show that a weak harmonic perturbation replicates these periodic windows giving rise to parameter regions correspondent to periodic orbits. The new windows are composed of parameters whose periodic orbits have the same periodicity and pattern of stable and unstable periodic orbits already existent for the unperturbed oscillator. Moreover, these unstable periodic orbits are embedded in chaotic attractors in phase space regions where the new stable orbits are identified. Thus, the observed periodic window replication is an effective oscillator control process, once chaotic orbits are replaced by regular ones.

  18. Large Acrylic Spherical Windows In Hyperbaric Underwater Photography

    Science.gov (United States)

    Lones, Joe J.; Stachiw, Jerry D.

    1983-10-01

    Both acrylic plastic and glass are common materials for hyperbaric optical windows. Although glass continues to be used occasionally for small windows, virtually all large viewports are made of acrylic. It is easy to uderstand the wide use of acrylic when comparing design properties of this plastic with those of glass, and glass windows are relatively more difficult to fabricate and use. in addition there are published guides for the design and fabrication of acrylic windows to be used in the hyperbaric environment of hydrospace. Although these procedures for fabricating the acrylic windows are somewhat involved, the results are extremely reliable. Acrylic viewports are now fabricated to very large sizes for manned observation or optical quality instrumen tation as illustrated by the numerous acrylic submersible vehicle hulls for hu, an occupancy currently in operation and a 3600 large optical window recently developed for the Walt Disney Circle Vision under-water camera housing.

  19. Measure Guideline: Energy-Efficient Window Performance and Selection

    Energy Technology Data Exchange (ETDEWEB)

    Carmody, J.; Haglund, K.

    2012-11-01

    This document provides guidelines for the selection of energy-efficient windows in new and existing residential construction in all US climate zones. It includes information on window products, their attributes and performance. It provides cost/benefit information on window energy savings as well as information on non-energy benefits such as thermal comfort and reduced HVAC demands. The document also provides information on energy impacts of design decisions such as window orientation, total glazing area and shading devices and conditions. Information on resources for proper window installation is included as well. This document is for builders, homeowners, designers and anyone making decisions about selecting energy efficient window. It is intended to complement other Building America information and efforts.

  20. Energy performance of windows based on the net energy gain

    DEFF Research Database (Denmark)

    Svendsen, Svend; Kragh, Jesper; Laustsen, Jacob Birck

    2005-01-01

    The paper presents a new method to set up energy performance requirements and energy classes for windows of all dimensions and configurations. The net energy gain of windows is the solar gain minus the heat loss integrated over the heating season. The net energy gain can be calculated for one...... orientation or averaged over different orientations. The averaged value may be used for energy labeling of windows of standard size. Requirements in building codes may also be based on the net energy gain instead of the thermal transmittance of the window. The size and the configuration of the window, i.......e. number of glazing units, have a very large effect on the net energy gain. Therefore the energy labeling or the requirements based on the standard size may not give valid information on the energy performance of windows of non-standard size. The paper presents a method to set up requirements and classes...

  1. Managing coherence via put/get windows

    Science.gov (United States)

    Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton on Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Ohmacht, Martin [Yorktown Heights, NY

    2012-02-21

    A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an area of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.

  2. 在KVM中安装Windows 10

    Institute of Scientific and Technical Information of China (English)

    薛民华; 解宝琦

    2015-01-01

    KVM是一个开源的系统虚拟化模块,自Linux2.6.20之后集成在Linux的各个主要发行版本中。最近,笔者就通过KVM进行了Windows10系统的安装,并就一些在安装中碰到的问题进行了解决。经过多次测试,终于成功完成了安装并使用良好。笔者将安装过程整理成该文,与大家分享。

  3. Window shrink contourlet coefficients for image denoising

    Institute of Scientific and Technical Information of China (English)

    JIN Wei; PAN Ying-jun; WEI Biao; FENG Peng

    2005-01-01

    An adaptive image denosing technique was proposed to achieve the tradeoff between details retain and noises removal. In order to achieve this objective, the contourlet transform was introduced and a new threshold method, namely CWinShrink, is presented. It shrinks the contourlet coefficients with adaptive shrinkage factors. The shrinkage factors were calculated with reference to the sum of squares of the contourlet coefficients within the neighborhood window. This approach achieves enhanced results for images those are corrupted with additive Gaussian noise. In numerical comparisons with various methods, for a set of noisy images ( the PSNR range from 10.86dB to 26.91dB) , the presented method outperforms VisuShrink and Wiener filter in terms of the PSNR. Experiments also show that this method not only keeps the details of image but also yields denoised images with better visual quality.

  4. Windows-Based Special Applications Router

    Directory of Open Access Journals (Sweden)

    Sufyan T. Faraj

    2009-01-01

    Full Text Available The design and implementation of an active router architecture that enables flexible network programmability based on so-called "user components" will be presents. This active router is designed to provide maximum flexibility for the development of future network functionality and services. The designed router concentrated mainly on the use of Windows Operating System, enhancing the Active Network Encapsulating Protocol (ANEP. Enhancing ANEP gains a service composition scheme which enables flexible programmability through integration of user components into the router's data path. Also an extended program that creates and then injects data packets into the network stack of the testing machine will be proposed, we will call this program the packet generator/injector (PGI. Finally, the success of the node architecture and its prototype implementation is evaluated by means of a few practical applications.

  5. A Tubular Aortopulmonary Window: An Embryological Curiosity.

    Science.gov (United States)

    Chidambarathanu, Shanthi; Agarwal, Ravi; Hussain, Zahra M; Brown, Nigel A; Anderson, Robert H

    2016-05-01

    We describe, in this report, an unusually shaped aortopulmonary communication observed in a six-month-old infant who presented with an associated ventricular septal defect. The defect was tubular, measuring 7 mm in length, and located intrapericardially between the proximal ascending aorta and the pulmonary trunk. It was well defined by transthoracic echocardiogram and was suitable for surgical ligation. We share our dilemma in naming this defect appropriately. We base our explanation on our understanding of normal development of the intrapericardial arterial trunks. There is initially an extensive aortopulmonary foramen. This is closed by apposition of a protrusion from the dorsal wall of the aortic sac, the aortopulmonary septum, with the distal margins of the outflow cushions. The spiral nature of formation of the aortopulmonary septum provides an understanding of the configuration of our tubular aortopulmonary window.

  6. INTEGRATED ENERGY EFFICIENT WINDOW-WALL SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Michael Arney, Ph.D.

    2002-12-31

    The building industry faces the challenge of reducing energy use while simultaneously improving construction methods and marketability. This paper describes the first phase of a project to address these concerns by designing an Integrated Window Wall System (IWWS) that can be commercialized. This work builds on previous research conducted during the 1990's by Lawrence Berkeley national Laboratories (LBNL). During this phase, the objective was to identify appropriate technologies, problems and issues and develop a number of design concepts. Four design concepts were developed into prototypes and preliminary energy analyses were conducted Three of these concepts (the foam wall, steel wall, and stiffened plate designs) showed particular potential for meeting the project objectives and will be continued into a second phase where one or two of the systems will be brought closer to commercialization.

  7. Porting salinas to the windows platform.

    Energy Technology Data Exchange (ETDEWEB)

    Reese, Garth M.; Wilson, Christopher Riley

    2006-06-01

    The ASC program has enabled significant development of high end engineering applications on massively parallel machines. There is a great benefit in providing these applications on the desktop of the analysts and designers, at least insofar as the small models may be run on these platforms, thus providing a tool set that spans the application needs. This effort documents the work of porting Salinas to the WINDOWS{trademark} platform. Selection of the tools required to compile, link, test and run Salinas in this environment is discussed. Significant problems encountered along the way are listed along with an estimation of the overall cost of the port. This report may serve as a baseline for streamlining further porting activities with other ASC codes.

  8. Managing coherence via put/get windows

    Energy Technology Data Exchange (ETDEWEB)

    Blumrich, Matthias A. (Ridgefield, CT); Chen, Dong (Croton on Hudson, NY); Coteus, Paul W. (Yorktown Heights, NY); Gara, Alan G. (Mount Kisco, NY); Giampapa, Mark E. (Irvington, NY); Heidelberger, Philip (Cortlandt Manor, NY); Hoenicke, Dirk (Ossining, NY); Ohmacht, Martin (Yorktown Heights, NY)

    2011-01-11

    A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an area of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.

  9. Supercomputers open window of opportunity for nursing.

    Science.gov (United States)

    Meintz, S L

    1993-01-01

    A window of opportunity was opened for nurse researchers with the High Performance Computing and Communications (HPCC) initiative in President Bush's 1992 fiscal-year budget. Nursing research moved into the high-performance computing environment through the University of Nevada Las Vegas/Cray Project for Nursing and Health Data Research (PNHDR). USing the CRAY YMP 2/216 supercomputer, the PNHDR established the validity of a supercomputer platform for nursing research. In addition, the research has identified a paradigm shift in statistical analysis, delineated actual and potential barriers to nursing research in a supercomputing environment, conceptualized a new branch of nursing science called Nurmetrics, and discovered new avenue for nursing research utilizing supercomputing tools.

  10. Simulating Complex Window Systems using BSDF Data

    Energy Technology Data Exchange (ETDEWEB)

    Konstantoglou, Maria; Jonsson, Jacob; Lee, Eleanor

    2009-06-22

    Nowadays, virtual models are commonly used to evaluate the performance of conventional window systems. Complex fenestration systems can be difficult to simulate accurately not only because of their geometry but also because of their optical properties that scatter light in an unpredictable manner. Bi-directional Scattering Distribution Functions (BSDF) have recently been developed based on a mixture of measurements and modelling to characterize the optics of such systems. This paper describes the workflow needed to create then use these BSDF datasets in the Radiance lighting simulation software. Limited comparisons are made between visualizations produced using the standard ray-tracing method, the BSDF method, and that taken in a full-scale outdoor mockup.

  11. Windows PowerShell脚本编写

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Windows PowerShell是微软公司为Windows环境所开发的外壳程序及命令行脚本语言技术,专门为系统管理设计。这项技术构建在.NET Framework之上,可帮助IT专业人士和超级用户控制及自动化在Windows上运行的Windows操作系统和应用程序的管理。发布两年多来,已有众多IT专业人士开始使用和深入了解它,那么目前国内的IT管理员们是否能够习惯它,编写的Power Shell脚本质量又如何呢?

  12. Windows on the axion. [quantum chromodynamics (QCD)

    Science.gov (United States)

    Turner, Michael S.

    1989-01-01

    Peccei-Quinn symmetry with attendant axion is a most compelling, and perhaps the most minimal, extension of the standard model, as it provides a very elegant solution to the nagging strong CP-problem associated with the theta vacuum structure of QCD. However, particle physics gives little guidance as to the axion mass; a priori, the plausible values span the range: 10(-12)eV is approx. less than m(a) which is approx. less than 10(6)eV, some 18 orders-of-magnitude. Laboratory experiments have excluded masses greater than 10(4)eV, leaving unprobed some 16 orders-of-magnitude. Axions have a host of interesting astrophysical and cosmological effects, including, modifying the evolution of stars of all types (our sun, red giants, white dwarfs, and neutron stars), contributing significantly to the mass density of the Universe today, and producting detectable line radiation through the decays of relic axions. Consideration of these effects has probed 14 orders-of-magnitude in axion mass, and has left open only two windows for further exploration: 10(-6)eV is approx. less than m(a) is approx. less than 10(-3)eV and 1eV is approx. less than m(a) is approx. less than 5eV (hadronic axions only). Both these windows are accessible to experiment, and a variety of very interesting experiments, all of which involve heavenly axions, are being planned or are underway.

  13. Facility Registry Service (FRS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Facility Registry Service (FRS) provides an integrated source of comprehensive (air, water, and waste) environmental information about facilities across EPA,...

  14. Licensed Healthcare Facilities

    Data.gov (United States)

    California Department of Resources — The Licensed Healthcare Facilities point layer represents the locations of all healthcare facilities licensed by the State of California, Department of Health...

  15. High Throughput Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Argonne?s high throughput facility provides highly automated and parallel approaches to material and materials chemistry development. The facility allows scientists...

  16. Aperture area measurement facility

    Data.gov (United States)

    Federal Laboratory Consortium — NIST has established an absolute aperture area measurement facility for circular and near-circular apertures use in radiometric instruments. The facility consists of...

  17. Environmental Toxicology Research Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Fully-equipped facilities for environmental toxicology research The Environmental Toxicology Research Facility (ETRF) located in Vicksburg, MS provides over 8,200 ft...

  18. Licensed Healthcare Facilities

    Data.gov (United States)

    California Department of Resources — The Licensed Healthcare Facilities point layer represents the locations of all healthcare facilities licensed by the State of California, Department of Health...

  19. Lysine 242 within helix 10 of the pseudorabies virus nuclear egress complex pUL31 component is critical for primary envelopment of nucleocapsids.

    Science.gov (United States)

    Rönfeldt, Sebastian; Klupp, Barbara G; Franzke, Kati; Mettenleiter, Thomas C

    2017-09-06

    Newly assembled herpesvirus nucleocapsids are translocated from the nucleus to the cytosol by a vesicle-mediated process engaging the nuclear membranes. This transport is governed by the conserved nuclear egress complex (NEC), consisting of the alphaherpesviral pUL34 and pUL31 homologs. The NEC is not only required for efficient nuclear egress but also sufficient for vesicle formation from the inner nuclear membrane (INM) as well as from synthetic lipid bilayers. The recently solved crystal structures for the NECs from different herpesviruses revealed molecular details of this membrane deformation and scission machinery uncovering the interfaces involved in complex and coat formation. However, the interaction domain with the nucleocapsid remained undefined. Since the NEC assembles a curved hexagonal coat on the nucleoplasmic side of the INM consisting of tightly interwoven pUL31/pUL34 heterodimers arranged in hexamers, only the membrane-distal end of the NEC formed by pUL31 residues appears accessible for interaction with the nucleocapsid cargo. To identify the amino acids involved in capsid incorporation we mutated the corresponding regions in the alphaherpesvirus pseudorabies virus (PrV). Site-specifically mutated pUL31 were tested for localization, interaction with pUL34 and complementation of PrV-ΔUL31. Here, we identify a conserved lysine residue at amino acid position 242 in PrV pUL31 located in the alpha-helical domain H10 exposed on the membrane-distal end of the NEC as a key residue for nucleocapsid incorporation into the nascent primary particle.IMPORTANCE Vesicular transport through the nuclear envelope is a focus of research but still not well understood. Herpesviruses pioneered this mechanism for translocation of the newly assembled nucleocapsid from the nucleus into the cytosol via vesicles derived from the inner nuclear membrane which fuse in a well-tuned process with the outer nuclear membrane to release their content. The structure of the viral

  20. SQLi te在 Windows 10 UWP中的应用

    Institute of Scientific and Technical Information of China (English)

    周辉; 赵峰; 马亮

    2016-01-01

    介绍 Windows UWP 和 SQLite的特点和体系结构。在 Windows 10上搭建 UWP App开发环境,阐述SQLite在UWP平台上的应用方法,利用SQLite for Universal Windows Platform 和SQLite .Net实现SQLite数据库的增加、删除、查询等操作。

  1. Windows Embedded Compact 7 CTP版正式发布

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    6月初,台北的Computex大展上微软正式公布了其嵌入式产品线最新的一员——Windows Embedded Compact7。Windows Embedded Compact7的前身就是家喻户晓的Windows Embedded CE系统(面向嵌入式应用的操作系统)。

  2. asymptotics for open-loop window flow control

    Directory of Open Access Journals (Sweden)

    Arthur W. Berger

    1994-01-01

    Full Text Available An open-loop window flow-control scheme regulates the flow into a system by allowing at most a specified window size W of flow in any interval of length L. The sliding window considers all subintervals of length L, while the jumping window considers consecutive disjoint intervals of length L. To better understand how these window control schemes perform for stationary sources, we describe for a large class of stochastic input processes the asymptotic behavior of the maximum flow in such window intervals over a time interval [0,T] as T and Lget large, with T substantially bigger than L. We use strong approximations to show that when T≫L≫logT an invariance principle holds, so that the asymptotic behavior depends on the stochastic input process only via its rate and asymptotic variability parameters. In considerable generality, the sliding and jumping windows are asymptotically equivalent. We also develop an approximate relation between the two maximum window sizes. We apply the asymptotic results to develop approximations for the means and standard deviations of the two maximum window contents. We apply computer simulation to evaluate and refine these approximations.

  3. Hey,Cortana——Windows 10介绍

    Institute of Scientific and Technical Information of China (English)

    约修亚_RK

    2015-01-01

    Windows10在2015年的7月29日正式释出,同时微软一直以来宣传的免费升级也成为了现实。在一年内,除了Windows RT和企业版以外的用户,都可以从Windows 7 SP1(Service Pack 1)或Windows 8.1免费升级。

  4. Windows Azure and ASP.NET MVC migration

    CERN Document Server

    Perkins, Benjamin

    2013-01-01

    Practical, real-world tools for migrating ASP.NET MVC to Windows Azure When IIS6 and Windows Server 2003 are no longer supported, you?ll need to migrate websites currently hosted on these technologies to newer technologies. This book comes to the rescue. It's packed with all the steps you need - all intertwined with real-world examples - to perform the migration of IIS6 and Windows Server 2003 websites to Windows Azure. Discusses different aspects of performance and scalability such as pipeline optimization, process model configuration, caching, minification, and bundling

  5. Sphere-cone-polynomial special window with good aberration characteristic

    Institute of Scientific and Technical Information of China (English)

    Wang Chao; Zhang Xin; Qu He-Meng; Wang Ling-Jie; Wang Yu

    2013-01-01

    Optical windows with external surfaces shaped to satisfy operational environment needs are known as special windows.A novel special window,a sphere-cone-polynomial (SCP) window,is proposed.The formulas of this window shape are given.An SCP MgF2 window with a fineness ratio of 1.33 is designed as an example.The field-of-regard (FOR) angle is ±75°.From the window system simulation results obtained with the calculated fluid dynamics (CFD) and optical design software,we find that compared to the conventional window forms,the SCP shape can not only introduce relatively less drag in the airflow,but also have the minimal effect on imaging.So the SCP window optical system can achieve a high image quality across a super wide FOR without adding extra aberration correctors.The tolerance analysis results show that the optical performance can be maintained with a reasonable fabricating tolerance to manufacturing errors.

  6. Windows Program For Driving The TDU-850 Printer

    Science.gov (United States)

    Parrish, Brett T.

    1995-01-01

    Program provides WYSIWYG compatibility between video display and printout. PDW is Microsoft Windows printer-driver computer program for use with Raytheon TDU-850 printer. Provides previously unavailable linkage between printer and IBM PC-compatible computers running Microsoft Windows. Enhances capabilities of Raytheon TDU-850 hardcopier by emulating all textual and graphical features normally supported by laser/ink-jet printers and makes printer compatible with any Microsoft Windows application. Also provides capabilities not found in laser/ink-jet printer drivers by providing certain Windows applications with ability to render high quality, true gray-scale photographic hardcopy on TDU-850. Written in C language.

  7. MCTS Windows 7 Configuration Study Guide, Exam 70-680

    CERN Document Server

    Panek, William

    2010-01-01

    Prepare for certification in Windows 7 configuration with this all-new study guide. This comprehensive book guides readers through preparation for Microsoft's brand new MCTS: Windows 7, Configuring exam (70-680). You'll find 100% coverage of all exam objectives; practical, real-world scenarios; hands-on exercises, and challenging review questions, both in the book and on the CD included with the book.: Prepares you for the new exam 70-680, the Microsoft Certified Technology Specialist certification for Windows 7; Windows 7 is Microsoft's new operating system releasing in late 2009; Shows you h

  8. Due-window assignment scheduling with variable job processing times.

    Science.gov (United States)

    Wu, Yu-Bin; Ji, Ping

    2015-01-01

    We consider a common due-window assignment scheduling problem jobs with variable job processing times on a single machine, where the processing time of a job is a function of its position in a sequence (i.e., learning effect) or its starting time (i.e., deteriorating effect). The problem is to determine the optimal due-windows, and the processing sequence simultaneously to minimize a cost function includes earliness, tardiness, the window location, window size, and weighted number of tardy jobs. We prove that the problem can be solved in polynomial time.

  9. Due-Window Assignment Scheduling with Variable Job Processing Times

    Directory of Open Access Journals (Sweden)

    Yu-Bin Wu

    2015-01-01

    Full Text Available We consider a common due-window assignment scheduling problem jobs with variable job processing times on a single machine, where the processing time of a job is a function of its position in a sequence (i.e., learning effect or its starting time (i.e., deteriorating effect. The problem is to determine the optimal due-windows, and the processing sequence simultaneously to minimize a cost function includes earliness, tardiness, the window location, window size, and weighted number of tardy jobs. We prove that the problem can be solved in polynomial time.

  10. Windows with an improved energy balance of 30%

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe

    The aim of the project has been to investigate and to develop thermally improved windows based on an evaluation of the energy balance of the window, i.e. the total influence of the window on the energy consumption for space heating. The energy balance is the net heat flow per window area which...... means that both energy losses and transmittance of solar radiation is considered.The final goal of the project was to improve the energy balance of a window with at least 30%. As reference is chosen a common low energy glazing mounted in a wooden frame construction measuring 1188 × 1188 mm2....... The transparent area forms about 68% of the total window area and the total U-value of the window is about 1.4 W/(m2 K).The energy balance depends strongly of the window orientation and the thermal mass of the room behind. In order to characterize the energy balance of a window with a single value a method has...

  11. Comparison of Windows and Linux Operating Systems in Advanced Features

    Directory of Open Access Journals (Sweden)

    P. Abhilash

    2015-02-01

    Full Text Available Comparison between the Microsoft Windows and Linux computer operating systems is a long-running discussion topic within the personal computer industry .This technical paper is mainly going to focus on the differences between windows and linux in all fields. Both Windows and Linux Operating systems have their own advantages and differ in functionalities and user friendliness. Linux and Microsoft Windows differ in philosophy, cost, versatility and stability, with each seeking to improve in their perceived weaker areas. This paper is mainly going to focus on the advanced features that are uniquely present in one operating system and not in other one.

  12. Expert T-SQL window functions in SQL Server

    CERN Document Server

    Kellenberger, Kathi

    2015-01-01

    Expert T-SQL Window Functions in SQL Server takes you from any level of knowledge of windowing functions and turns you into an expert who can use these powerful functions to solve many T-SQL queries. Replace slow cursors and self-joins with queries that are easy to write and fantastically better performing, all through the magic of window functions. First introduced in SQL Server 2005, window functions came into full blossom with SQL Server 2012. They truly are one of the most notable developments in SQL in a decade, and every developer and DBA can benefit from their expressive power in sol

  13. Guide to research facilities

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-01

    This Guide provides information on facilities at US Department of Energy (DOE) and other government laboratories that focus on research and development of energy efficiency and renewable energy technologies. These laboratories have opened these facilities to outside users within the scientific community to encourage cooperation between the laboratories and the private sector. The Guide features two types of facilities: designated user facilities and other research facilities. Designated user facilities are one-of-a-kind DOE facilities that are staffed by personnel with unparalleled expertise and that contain sophisticated equipment. Other research facilities are facilities at DOE and other government laboratories that provide sophisticated equipment, testing areas, or processes that may not be available at private facilities. Each facility listing includes the name and phone number of someone you can call for more information.

  14. Contaminations of inner surface of magnesium fluoride windows in the `Expose-R' experiment on the International Space Station

    Science.gov (United States)

    Skurat, V. E.

    2017-10-01

    A series of experiments was carried out previously on board of the International Space Station in `EXPOSE-R', a multi-user expose facility, provided by European Space Agency attached to the external surface of the Russian Segment. In one experiment, spores of microorganisms and species of higher plant seeds, in heat-sealed polymer bags were irradiated by solar radiation passed through MgF2 windows in a high space vacuum. After sample exposure, it was found that in many cases the inner surfaces of windows were contaminated. Analysis of the contamination revealed the presence of chemical groups CH2, CH3, NH, OH, C═O, Si-CH3 (Demets et al. in 2015). Their presence in deposits was explained by photofixation of gaseous precursors - some of the vapours of glues and additives in polymeric materials in the core facility of `Expose-R'. Carbon-, oxygen- and silicon-containing groups may be deposited from outer intrinsic atmosphere. This atmosphere is connected with sample compartments and core facility. However, the presence of NH groups on inner surfaces of windows was not expected. This paper shows that the process responsible for carbon-, nitrogen- and oxygen-containing group formation can be a photopolymerization of caprolactam, which is released from the outer Nylon 6 layer of polymer bags under Solar vacuum ultraviolet radiation.

  15. Windows Biometirc Framework系统简介%The Brief Introduction of Windows Biometric Framework

    Institute of Scientific and Technical Information of China (English)

    郑嘉彦

    2012-01-01

    随着生物科技的成熟发展,在如今的计算机安全领域,指纹系统认证已经越来越被广泛运用.各个笔记本厂商也相继推出带有指纹处理芯片的高端笔记本电脑.在windows7系统中,微软为指纹设备驱动与指纹认证系统应用程序之间的链接定义一系列框架——windows biometric framework,本文将对这一系统框架做一简单简介.

  16. "Visual"时代Windows API函数的使用%Application of Windows API Function in Visual Times

    Institute of Scientific and Technical Information of China (English)

    杨平; 李建武; 李茗

    2004-01-01

    在"Visual"时代,Windows API函数是进入操作系统核心进行高级编程的重要工具.本文介绍了Windows API函数概念,通过示例分析如何在Visual Basic、Delphi、Visual C++等语言中使用Windows API函数对操作系统核心进行编程.

  17. Surveillance studies about "rear-window ethics"%Surveillance studies about"rear-window ethics"

    Institute of Scientific and Technical Information of China (English)

    黄婷婷

    2016-01-01

    It can be said that people now live in a surveillance society. Some forms of surveillance have always existed as people watch over each other for mutual care, for moral caution and to discover information under the table. Alfred Hitchcock's Rear Window is a typical fi lm for surveillance studies.What is happening on the screen is merely a projection of our own anxieties, our own existence, and our self-ambiguity as portrayed by the characters in this wonderful film.

  18. Facility and test support equipment for the manned thermal vacuum tests of the Apollo Soyuz docking module

    Science.gov (United States)

    Pearson, O. L.

    1975-01-01

    In order to accommodate manned thermal-vacuum testing of the Apollo-Soyuz docking module (ASDM), modifications to the facility, cleanliness and access control, and special test equipment were required. Facility modifications discussed briefly include: the addition of an oxygen supply system; the modification of manlock (ML) piping for cleaning and access controls; the addition of a nitrogen diluent system; the removal of manlock internal lights and the addition of external lights as well as fusing all power circuits over 10 watts; the removal/containment of flammable materials; the upgrading of a ML fire suppression system; and the addition of a garment donning station for cleanliness control. Special test equipment discussed include: an access tunnel for crew ingress/egress; a support device for the docking module (DM) and simulators; a command module thermal simulator; a DM infrared (IR) simulator; a docking system IR simulator; a metabolic heat load simulator; and a television camera simulator.

  19. The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress.

    Science.gov (United States)

    Milbradt, Jens; Hutterer, Corina; Bahsi, Hanife; Wagner, Sabrina; Sonntag, Eric; Horn, Anselm H C; Kaufer, Benedikt B; Mori, Yasuko; Sticht, Heinrich; Fossen, Torgils; Marschall, Manfred

    2016-08-01

    The nuclear lamina lines the inner nuclear membrane providing a structural framework for the nucleus. Cellular processes, such as nuclear envelope breakdown during mitosis or nuclear export of large ribonucleoprotein complexes, are functionally linked to the disassembly of the nuclear lamina. In general, lamina disassembly is mediated by phosphorylation, but the precise molecular mechanism is still not completely understood. Recently, we suggested a novel mechanism for lamina disassembly during the nuclear egress of herpesviral capsids which involves the cellular isomerase Pin1. In this study, we focused on mechanistic details of herpesviral nuclear replication to demonstrate the general importance of Pin1 for lamina disassembly. In particular, Ser22-specific lamin phosphorylation consistently generates a Pin1-binding motif in cells infected with human and animal alpha-, beta-, and gammaherpesviruses. Using nuclear magnetic resonance spectroscopy, we showed that binding of Pin1 to a synthetic lamin peptide induces its cis/trans isomerization in vitro. A detailed bioinformatic evaluation strongly suggests that this structural conversion induces large-scale secondary structural changes in the lamin N-terminus. Thus, we concluded that a Pin1-induced conformational change of lamins may represent the molecular trigger responsible for lamina disassembly. Consistent with this concept, pharmacological inhibition of Pin1 activity blocked lamina disassembly in herpesvirus-infected fibroblasts and consequently impaired virus replication. In addition, a phospho-mimetic Ser22Glu lamin mutant was still able to form a regular lamina structure and overexpression of a Ser22-phosphorylating kinase did not induce lamina disassembly in Pin1 knockout cells. Intriguingly, this was observed in absence of herpesvirus infection proposing a broader importance of Pin1 for lamina constitution. Thus, our results suggest a functional model of similar events leading to disassembly of the nuclear

  20. Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase.

    Science.gov (United States)

    Wisner, Todd W; Wright, Catherine C; Kato, Akihisa; Kawaguchi, Yasushi; Mou, Fan; Baines, Joel D; Roller, Richard J; Johnson, David C

    2009-04-01

    Herpesvirus capsids collect along the inner surface of the nuclear envelope and bud into the perinuclear space. Enveloped virions then fuse with the outer nuclear membrane (NM). We previously showed that herpes simplex virus (HSV) glycoproteins gB and gH act in a redundant fashion to promote fusion between the virion envelope and the outer NM. HSV mutants lacking both gB and gH accumulate enveloped virions in herniations, vesicles that bulge into the nucleoplasm. Earlier studies had shown that HSV mutants lacking the viral serine/threonine kinase US3 also accumulate herniations. Here, we demonstrate that HSV gB is phosphorylated in a US3-dependent manner in HSV-infected cells, especially in a crude nuclear fraction. Moreover, US3 directly phosphorylated the gB cytoplasmic (CT) domain in in vitro assays. Deletion of gB in the context of a US3-null virus did not add substantially to defects in nuclear egress. The majority of the US3-dependent phosphorylation of gB involved the CT domain and amino acid T887, a residue present in a motif similar to that recognized by US3 in other proteins. HSV recombinants lacking gH and expressing either gB substitution mutation T887A or a gB truncated at residue 886 displayed substantial defects in nuclear egress. We concluded that phosphorylation of the gB CT domain is important for gB-mediated fusion with the outer NM. This suggested a model in which the US3 kinase is incorporated into the tegument layer (between the capsid and envelope) in HSV virions present in the perinuclear space. By this packaging, US3 might be brought close to the gB CT tail, leading to phosphorylation and triggering fusion between the virion envelope and the outer NM.